BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P0A988
(366 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
6E8E-B nrPDB 754 0.0
5X06-A nrPDB 753 0.0
4TR8-A nrPDB 393 e-110
6AP4-A nrPDB 309 1e-84
5WCE-A nrPDB 249 1e-66
6DEG-A nrPDB 249 2e-66
6MAN-A nrPDB 187 7e-48
6D46-A nrPDB 184 5e-47
5W7Z-A nrPDB 182 2e-46
4TR6-A nrPDB 159 3e-39
6E8D-A nrPDB 158 3e-39
1VPK-A nrPDB 158 4e-39
4TRT-A nrPDB 137 7e-33
3P16-A nrPDB 132 2e-31
5AH4-A nrPDB 125 4e-29
6D47-A nrPDB 124 7e-29
2AVT-A nrPDB 123 1e-28
2AWA-A nrPDB 118 5e-27
3T0P-A nrPDB 106 2e-23
6DJ8-A nrPDB 89 3e-18
4S3I-A nrPDB 81 7e-16
5Y86-A nrPDB 30 1.9
3HPX-A nrPDB 30 2.0
3MWB-A nrPDB 29 2.8
3HQ1-A nrPDB 29 3.3
4EWP-A nrPDB 28 5.9
3BH7-B nrPDB 28 6.7
>6E8E-B nrPDB
Length = 517
Score = 754 bits (1946), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV
Sbjct: 39 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 98
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD
Sbjct: 99 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 158
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC
Sbjct: 159 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 218
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240
SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR
Sbjct: 219 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 278
Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300
FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE
Sbjct: 279 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 338
Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360
EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV
Sbjct: 339 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 398
Query: 361 VMPMRL 366
VMPMRL
Sbjct: 399 VMPMRL 404
>5X06-A nrPDB
Length = 386
Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV
Sbjct: 21 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 80
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD
Sbjct: 81 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 140
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC
Sbjct: 141 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 200
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240
SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR
Sbjct: 201 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 260
Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300
FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE
Sbjct: 261 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 320
Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360
EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV
Sbjct: 321 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 380
Query: 361 VMPMRL 366
VMPMRL
Sbjct: 381 VMPMRL 386
>4TR8-A nrPDB
Length = 383
Score = 393 bits (1009), Expect = e-110, Method: Compositional matrix adjust.
Identities = 205/369 (55%), Positives = 267/369 (72%), Gaps = 5/369 (1%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
M FT++RE LLKPLQ V+G + R TLP+L N+LL V LSLTGTDLE+E+V RV L
Sbjct: 17 MHFTIQREALLKPLQLVAGVVERRQTLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLE 76
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
EPG TVPARK DIC+ LP I +++E +++LV++GRSRF+LSTLPA DFP ++
Sbjct: 77 DAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPTVE 136
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ + F++ Q+ ++RLI+ T F+MA QDVRYYLNGML E G LR+VATDGHRLA+C
Sbjct: 137 EGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMC 196
Query: 181 SMPIGQSLPS---HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLV 237
S+ +PS H VIVPRKG++EL R+L D + + +G ++IRA G+F FTSKLV
Sbjct: 197 SLD--AQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLV 254
Query: 238 DGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNP 297
DG+FPDY RVLP+ DK + L++AF+R AILSNEK+RG+RL +S LKI ANNP
Sbjct: 255 DGKFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNP 314
Query: 298 EQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSA 357
EQEEAEE + V Y+G +EIGFNVSY+LDVL + E VR +L+DS SS + +A + +
Sbjct: 315 EQEEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDS 374
Query: 358 AYVVMPMRL 366
AYVVMPMRL
Sbjct: 375 AYVVMPMRL 383
>6AP4-A nrPDB
Length = 388
Score = 309 bits (792), Expect = 1e-84, Method: Compositional matrix adjust.
Identities = 174/383 (45%), Positives = 236/383 (61%), Gaps = 18/383 (4%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
M+ + +E LL L V G + R TL IL N+ +Q L++TG+DLE+E+VA AL
Sbjct: 7 MRLKIAKESLLNVLSHVVGAVERRHTLNILSNVKIQTNAQALTITGSDLEVELVASTALS 66
Query: 61 QPH--EPGATTVPARKFFDICRGLPEGAEIAVQL-EGERMLVRSGRSRFSLSTLPAADFP 117
+ E G TTVPARK +IC+ LP A I +Q+ E +R +++SG SRF L TLPA D+P
Sbjct: 67 EGACLEAGETTVPARKLMEICKSLPTAALIDLQITEDQRCILKSGNSRFVLGTLPAEDYP 126
Query: 118 NLDDWQSE-VEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHR 176
L S+ + + Q +KRL E T F+MA QDVR+YL G L E + +LR V TDGHR
Sbjct: 127 LLTTENSQGTQVQVTQRELKRLFEKTAFAMAVQDVRFYLTGTLLEIDENQLRAVTTDGHR 186
Query: 177 LAVCSMPIGQSLPSHSV--IVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHV------- 227
LA+C + + S S V IVPRK V EL R+L D L + IG + +
Sbjct: 187 LALCEI-LASSTSSQLVQAIVPRKAVGELQRLLSIEDEQLTLLIGRELLNVTINTPSRDK 245
Query: 228 --GDFI--FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRL 283
GD FT+KL+DG+FPDYRRV+P+ DKH+ G D+ KQ+ R AILSNEK RGV L
Sbjct: 246 EQGDITVRFTTKLIDGKFPDYRRVIPRGGDKHVLIGHDVFKQSLQRVAILSNEKLRGVFL 305
Query: 284 YVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDS 343
+++ L++ ANNPEQ+EA E L + Y A +E+ FN Y+LDVL L ++V M +T++
Sbjct: 306 NFNQDSLQLRANNPEQDEAIEDLAIQYQSAPLEMSFNAQYLLDVLGVLDGDDVNMSMTEA 365
Query: 344 VSSVQIEDAASQSAAYVVMPMRL 366
SV ++D A YVVMPMR+
Sbjct: 366 NQSVLVQDPAHPDQTYVVMPMRV 388
>5WCE-A nrPDB
Length = 379
Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 141/373 (37%), Positives = 206/373 (55%), Gaps = 8/373 (2%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK T+ER LLK L V + R T+PIL N+LL LS + TDL+ME++
Sbjct: 8 MKLTIERAALLKALGHVQSVVERRNTIPILSNILLSAEGDRLSFSATDLDMEIIDE-GFA 66
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE--RMLVRSGRSRFSLSTLPAADFPN 118
Q PG T PA ++I R LP+GA++++ G+ R+++++GRSRF+L LPA DFP
Sbjct: 67 QIDVPGQITAPAHTLYEIVRKLPDGADVSLSFSGDDPRLVIQAGRSRFNLPVLPAGDFPV 126
Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFET--EGEE--LRTVATDG 174
+ + + RLI+ T+F+++ ++ RYYLNG+ T EG E LR VATDG
Sbjct: 127 MSSDGLSSRIAVDTNELIRLIDKTRFAISTEETRYYLNGLYVHTVNEGGETKLRAVATDG 186
Query: 175 HRLAVCSMPIGQ-SLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233
HRLA+ MP + ++ VIVPRK + E R+++ + +Q+ +R G T
Sbjct: 187 HRLALAEMPAPEGAVGIPGVIVPRKTIAEARRLMESAGETVDLQVSPQKVRFEFGAAALT 246
Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293
SK++DG FPDY RV+P++ K L DL +A R A +S EK R V+L V ++ +T
Sbjct: 247 SKVIDGAFPDYMRVIPRDNAKILTLDNDLFAKAVDRVATISAEKSRSVKLAVEPGRITLT 306
Query: 294 ANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAA 353
N E +A E ++V Y G EIGFN Y+LDV + D S + D
Sbjct: 307 VRNMEAGQAVEEVEVDYDGEPFEIGFNARYLLDVCGQIAGPQAEFRFADPASPTLVVDPV 366
Query: 354 SQSAAYVVMPMRL 366
YV+MP+R+
Sbjct: 367 DPGVKYVLMPLRV 379
>6DEG-A nrPDB
Length = 381
Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust.
Identities = 144/376 (38%), Positives = 213/376 (56%), Gaps = 13/376 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
M+ TV+R K L +V + R T+PIL N+L+ +G++ L TDL++E V V
Sbjct: 9 MRITVDRSQFFKSLGRVHRVVERRNTVPILSNVLIDAENGSVQLKATDLDLE-VTESFTV 67
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQL---EGERMLVRSGRSRFSLSTLPAADFP 117
+ GA TVPA +DI R LP+G+EI + + + M + SG + F L LP DFP
Sbjct: 68 NIEKAGAITVPAYLLYDIVRKLPDGSEIVLSVDENQASAMSIVSGCTHFQLQCLPKIDFP 127
Query: 118 NLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEE---LRTVATDG 174
Q F L + +K L++ TQF+++ ++ RYYLNG+ F ++ LR VATDG
Sbjct: 128 ESLPGQFGCRFFLSASKLKHLLDCTQFAISTEETRYYLNGIYFHIVHDDVLKLRLVATDG 187
Query: 175 HRLAVCSM--PIG-QSLPSHSVIVPRKGVIELMRML-DGGDNPLRVQIGSNNIRAHVGDF 230
HRLA M P G +P VI+PRK V EL ++L + D + +++ IR +G
Sbjct: 188 HRLAQVDMEAPSGVDGMPG--VIIPRKAVGELQKLLSEEIDGDVCIELSETKIRFSLGSV 245
Query: 231 IFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQL 290
+FTSKLVDG FPDY+RV+P D+ L A R + +SN++ R V+L + QL
Sbjct: 246 VFTSKLVDGTFPDYQRVIPLGNDRKLIVNRQDFSSAVDRVSTISNDRGRAVKLTIEHGQL 305
Query: 291 KITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350
K+ NNP+ AE+ L TY+ +EIGFN Y+LD+ L + + ML+D+V+ I
Sbjct: 306 KLVVNNPDSGSAEDQLAATYTSEPLEIGFNSRYLLDIAGQLSSDEMVFMLSDAVAPALIR 365
Query: 351 DAASQSAAYVVMPMRL 366
D + YV+MP+R+
Sbjct: 366 DNNNAEVLYVLMPVRV 381
>6MAN-A nrPDB
Length = 387
Score = 187 bits (474), Expect = 7e-48, Method: Compositional matrix adjust.
Identities = 114/379 (30%), Positives = 194/379 (51%), Gaps = 14/379 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+K VE + L++ L S + R + L N+ L DG L L+ T++++ + ++ V
Sbjct: 10 LKVIVETKTLVQALGFASSVVEKRNIISELANIKLLAKDGLLELSSTNMDLYLSQKIG-V 68
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
Q G TV + DI + LP+ L + + RF+L TLP FP +D
Sbjct: 69 QVVSEGELTVSTKTLNDIVKKLPDSELTLTDLGTTGLEITGKNCRFNLFTLPVESFPVMD 128
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ E F + A ++IE+T+FS++ + RY LNG+ + E +TDGHRL+V
Sbjct: 129 NINPEASFKISCAEFAKIIESTKFSVSLDETRYNLNGIYLHVKDSEFYAASTDGHRLSVS 188
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNP---LRVQIGSNNIRAHVG-DFIFTSKL 236
S+ + + + VI+P+K E+++++ N + + + SN I+ + I SKL
Sbjct: 189 SVVLAEKIEDFGVILPQKSAEEILKIVKDSKNANADIEILLSSNKIKFICNENVIMLSKL 248
Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296
+DG FPDY +P+N L + R AI++ EKFR V+L +S L+I+A
Sbjct: 249 IDGTFPDYSSFIPENSSSKLVINRKIFADTIERIAIITVEKFRAVKLSLSGEALEISAIG 308
Query: 297 PEQEEAEEILDVT--------YSG-AEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347
+ A+E+++ + YSG ++IGFN Y+ DVL A+K + V + + + V
Sbjct: 309 EARGNAKEVINSSKETENFYEYSGETNLDIGFNPQYLEDVLKAIKSDLVELYFSSVSAPV 368
Query: 348 QIEDAASQSAAYVVMPMRL 366
I+ S +VVMP+++
Sbjct: 369 LIKFPESPKDIFVVMPVKV 387
>6D46-A nrPDB
Length = 389
Score = 184 bits (467), Expect = 5e-47, Method: Compositional matrix adjust.
Identities = 112/381 (29%), Positives = 201/381 (52%), Gaps = 16/381 (4%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+K VE + L++ L + R +P N+ L DG L L+ T++++ + ++A V
Sbjct: 10 LKLIVETKTLVQSLGFARSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
Q G TV + DI R LP+ +L+ ++ ++ +F+L TLP + FP +D
Sbjct: 69 QVLSEGEITVSTQTLSDIVRKLPDSELTLTELDIMKLEIKGQNCQFNLFTLPVSSFPAMD 128
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ EV F + A ++IE+T+FS++ + RY LNG+ + +E +TDGHRL++
Sbjct: 129 SIKPEVSFKISCADFAKIIESTKFSISLDETRYNLNGIYLHIKDKEFFAASTDGHRLSIS 188
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDN---PLRVQIGSNNIRAHVG-DFIFTSKL 236
+ + + + + VI+P+K E+++++ N + + + SN I+ + I SKL
Sbjct: 189 WITLEEKIKNFGVILPQKSAEEILKIVKDLKNIHEDIEILLSSNKIKFICNENTILLSKL 248
Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296
+DG FPDY +PK+ L + + R AI++ EKFR ++L +S L+I+A
Sbjct: 249 IDGTFPDYSAFIPKSSISKLVINRKIFADSIERIAIITVEKFRAIKLSLSRKTLEISAVG 308
Query: 297 PEQEEAEEILDVT--------YSGAE-MEIGFNVSYVLDVLNALKCENVRMMLTDSVSS- 346
+ A+EI+ + Y+ E + IGFN Y+ DVL A+K V + +D +S
Sbjct: 309 EARGNAKEIITASQDKESFYEYNCDESLVIGFNPQYLEDVLKAVKSNLVELYFSDISASA 368
Query: 347 -VQIEDAASQSAAYVVMPMRL 366
V I+ + +V+MP+++
Sbjct: 369 PVLIKFPQNPKDIFVIMPVKV 389
>5W7Z-A nrPDB
Length = 387
Score = 182 bits (462), Expect = 2e-46, Method: Compositional matrix adjust.
Identities = 109/379 (28%), Positives = 197/379 (51%), Gaps = 14/379 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+K VE + L++ L S + R +P N+ L DG L L+ T++++ + ++A V
Sbjct: 10 LKLIVETKTLVQSLGFASSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
Q G TV + DI R LP+ L + ++ +F+L TLP + FP +D
Sbjct: 69 QVVSEGECTVSTKTLNDIVRKLPDSELTLTDLGTTGLEIKGKNCKFNLFTLPVSSFPAMD 128
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
E F + ++IE+T+FS++ + RY LNG+ + +E + +TDGHRL++
Sbjct: 129 SINPEASFKISCTDFAKIIESTKFSISLDETRYNLNGVYLHIKDKEFCSASTDGHRLSIS 188
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDN---PLRVQIGSNNIRAHVGDFI-FTSKL 236
+ + + + + VI+P+K E+++++ N + + + SN I+ + SKL
Sbjct: 189 WVTLEKQIKNFGVILPQKSAEEILKIVKDPKNINEDIEILLSSNKIKFICNENTSMLSKL 248
Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296
+DG FPDY +P++ L + + R AI++ EKFR V+L +S L+I+A
Sbjct: 249 IDGTFPDYSTFIPESSSSKLVINRKMFADSIERIAIITVEKFRAVKLSLSRETLEISAVG 308
Query: 297 PEQEEAEEILDVT--------YSGAE-MEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347
+ A+E+++ + Y+ E + IGFN Y+ DVL A+K + V + +D + V
Sbjct: 309 EARGNAKEVINSSQDKESFYEYNSDESLAIGFNPQYLEDVLKAVKSDVVELYFSDVSAPV 368
Query: 348 QIEDAASQSAAYVVMPMRL 366
I+ + +VVMP+++
Sbjct: 369 LIKFPENPKDIFVVMPVKV 387
>4TR6-A nrPDB
Length = 380
Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 100/379 (26%), Positives = 200/379 (52%), Gaps = 17/379 (4%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARV--- 57
MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + +
Sbjct: 3 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 62
Query: 58 ----ALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112
+V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L
Sbjct: 63 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 121
Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172
A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT
Sbjct: 122 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 181
Query: 173 DGHRLAVCSMPIGQSLP---SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD 229
D HRLA+ + +P S++V++P K + EL ++LD + + I + +
Sbjct: 182 DSHRLALRKAKL--DIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKN 239
Query: 230 FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE-- 287
+F S+L+DG +PD ++P++ + QA RA++L+ E V ++
Sbjct: 240 VLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPA 299
Query: 288 NQLKITANNPE-QEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSS 346
++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++
Sbjct: 300 ESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRP 359
Query: 347 VQIEDAASQSAAYVVMPMR 365
I ++ +++P+R
Sbjct: 360 FLIRTPNDETIVQLILPVR 378
>6E8D-A nrPDB
Length = 512
Score = 158 bits (400), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 100/379 (26%), Positives = 200/379 (52%), Gaps = 17/379 (4%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARV--- 57
MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + +
Sbjct: 39 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 98
Query: 58 ----ALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112
+V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L
Sbjct: 99 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 157
Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172
A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT
Sbjct: 158 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 217
Query: 173 DGHRLAVCSMPIGQSLP---SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD 229
D HRLA+ + +P S++V++P K + EL ++LD + + I + +
Sbjct: 218 DSHRLALRKAKL--DIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKN 275
Query: 230 FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE-- 287
+F S+L+DG +PD ++P++ + QA RA++L+ E V ++
Sbjct: 276 VLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPA 335
Query: 288 NQLKITANNPE-QEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSS 346
++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++
Sbjct: 336 ESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRP 395
Query: 347 VQIEDAASQSAAYVVMPMR 365
I ++ +++P+R
Sbjct: 396 FLIRTPNDETIVQLILPVR 414
>1VPK-A nrPDB
Length = 378
Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 101/368 (27%), Positives = 178/368 (48%), Gaps = 5/368 (1%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK TV L + S L + PIL L +V DG + TDLE + A V
Sbjct: 13 MKVTVTTLELKDKITIASKALAKKSVKPILAGFLFEVKDGNFYICATDLETGVKATVNAA 72
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIA-VQLEGERMLVRSGRSRFSLSTLPAADFPNL 119
+ VP + + LP+ EI + LEG+ +++ SG + F ++T+PA +FP +
Sbjct: 73 EISGEARFVVPGDVIQKMVKVLPD--EITELSLEGDALVISSGSTVFRITTMPADEFPEI 130
Query: 120 DDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAV 179
+S + F + + ++ ++E F+ A + LNG+ +E LR VA+DG RLA+
Sbjct: 131 TPAESGITFEVDTSLLEEMVEKVIFAAAKDEFMRNLNGVFWELHKNLLRLVASDGFRLAL 190
Query: 180 CSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNP-LRVQIGSNNIRAHVGDFIFTSKLVD 238
I + S ++ K + E+ +LD P + V+ + D ++VD
Sbjct: 191 AEEQIENEEEA-SFLLSLKSMKEVQNVLDNTTEPTITVRYDGRRVSLSTNDVETVMRVVD 249
Query: 239 GRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPE 298
FPDY+RV+P+ + L+++ R +++++ V+ + EN +++ + +P+
Sbjct: 250 AEFPDYKRVIPETFKTKVVVSRKELRESLKRVMVIASKGSESVKFEIEENVMRLVSKSPD 309
Query: 299 QEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAA 358
E + ++V G ++ I FN ++ DVL ++ E + M DS S QI
Sbjct: 310 YGEVVDEVEVQKEGEDLVIAFNPKFIEDVLKHIETEEIEMNFVDSTSPCQINPLDISGYL 369
Query: 359 YVVMPMRL 366
Y+VMP+RL
Sbjct: 370 YIVMPIRL 377
>4TRT-A nrPDB
Length = 368
Score = 137 bits (345), Expect = 7e-33, Method: Compositional matrix adjust.
Identities = 102/348 (29%), Positives = 175/348 (50%), Gaps = 12/348 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK V ++ L + L + + R + P+L L ++ ++G L+L+GT+LE+++ V
Sbjct: 2 MKANVTKKTLNEGLGLLERVIPSRSSNPLLTALKVETSEGGLTLSGTNLEIDLSCFVP-A 60
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ +P VPA F I R L G + ++L G+ + VRSG S F L T +P L
Sbjct: 61 EVQQPENFVVPAHLFAQIVRNLG-GELVELELSGQELSVRSGGSDFKLQTGDIEAYPPLS 119
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ ++ + +L + R + +++ +++ + G+ E GE R VA+DG+R+A+
Sbjct: 120 -FPAQADVSLDGGELSRAFSSVRYAASNEAFQAVFRGIKLEHHGESARVVASDGYRVAIR 178
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240
P S ++I+P + V EL+R+L G+ R G + KL+DG
Sbjct: 179 DFP--ASGDGKNLIIPARSVDELIRVLKDGE--ARFTYGDGMLTVTTDRVKMNLKLLDGD 234
Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNPEQ 299
FPDY RV+PK+ + LK+A R A+L+++ V VSE L++ A +
Sbjct: 235 FPDYERVIPKDIKLQVTLPATALKEAVNRVAVLADKNANNRVEFLVSEGTLRLAAEG-DY 293
Query: 300 EEAEEILDVTYSGAE--MEIGFNVSYVLDVLNALKCENVRMMLTDSVS 345
A++ L VT G E M + FN +VLD L + + ++ + S S
Sbjct: 294 GRAQDTLSVTQGGTEQAMSLAFNARHVLDALGPIDGD-AELLFSGSTS 340
>3P16-A nrPDB
Length = 408
Score = 132 bits (333), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 110/393 (27%), Positives = 178/393 (45%), Gaps = 32/393 (8%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+ F + RE + V+ L RP +P+L +LL +D L+++G D E+ A+V
Sbjct: 19 LTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVG-A 77
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ PG+ V R DI R LP + V +EG R+ + G +RFSL T+P D+P L
Sbjct: 78 EIVSPGSVLVSGRLLSDITRALPN-KPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLP 136
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
E LP I + D L G+ E GE + ATD RLAV
Sbjct: 137 TLPEETGL-LPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVR 195
Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIF------ 232
+ S P +V+VP K + E + GG + +R+ +G+ G
Sbjct: 196 ELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSD-VRLSLGTGPGVGKDGLLGISGNGKR 254
Query: 233 -TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLK 291
T++L+D FP +R++LP L +A A++++ + VR+ ++ ++
Sbjct: 255 STTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQ-VRMEFADGSVR 313
Query: 292 ITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDS-----VSS 346
++A + AEE L V Y+G + I FN +Y+ D L++L+ E V T + +
Sbjct: 314 LSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRP 373
Query: 347 VQIED-------------AASQSAAYVVMPMRL 366
V +D A S Y++MP+RL
Sbjct: 374 VSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRL 406
>5AH4-A nrPDB
Length = 401
Score = 125 bits (313), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 113/393 (28%), Positives = 177/393 (45%), Gaps = 35/393 (8%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+KF V RE + V+ L RPT+P+L +LL D L+++G D E+ +V+
Sbjct: 15 LKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVS-A 73
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ G+ V R DI + LP + V +EG R+ + G +RFSL TL D+P L
Sbjct: 74 EIASAGSVLVSGRLLSDITKALP-AKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALP 132
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
E + I + D L G+ E GE + ATD RLAV
Sbjct: 133 ALPEETGV-IASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVR 191
Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVG-DFIF----- 232
+ + +V+VP K + E + G N + + +GS A VG D +
Sbjct: 192 ELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDG-NQVHLALGSG---ASVGKDGLLGIRSE 247
Query: 233 ----TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSEN 288
T++L+D FP +R++LP G L +A R A++++ + +R+ S++
Sbjct: 248 GKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQ-IRMEFSDD 306
Query: 289 QLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTD----SV 344
LK++A + AEE L V ++G + I FN +Y+ D L +L E V T +V
Sbjct: 307 TLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAV 366
Query: 345 SSVQIED-----------AASQSAAYVVMPMRL 366
ED AA Y++MP+RL
Sbjct: 367 LRPAGEDDGANGGSGPFPAAKTDYVYLLMPVRL 399
>6D47-A nrPDB
Length = 410
Score = 124 bits (310), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 99/349 (28%), Positives = 162/349 (46%), Gaps = 12/349 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+KF + RE + V+ L RP +P+L +LL +D L+++G D E+ RV
Sbjct: 21 LKFRLVRESFADAVSWVAKNLPTRPAVPVLSGVLLTGSDEGLTISGFDYEVSAEVRVP-A 79
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ PG V R DI R LP + ++G R+ + G +RFSL T+ D+P L
Sbjct: 80 EIASPGTVLVSGRLLSDITRALPN-KPVDFYVDGNRVALTCGNARFSLPTMAVEDYPTLP 138
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ TLP I + D L G+ E GE++ ATD RLAV
Sbjct: 139 TLPEDTG-TLPAELFSEAIGQVAIAAGRDDTLPMLTGIRVEISGEKVVLAATDRFRLAVR 197
Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRM-LDGGDNPLRVQ----IGSNNIRAHVGDFI-F 232
+ P +V+VP K + E + DG + L + +G + + GD
Sbjct: 198 ELTWNALSPDIEAAVLVPAKTLGEAAKANTDGSEVRLSLGAGMGVGKDGLLGISGDGKRS 257
Query: 233 TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKI 292
T++L+D FP +R++LP A L +A A++++ + VR+ ++ L++
Sbjct: 258 TTRLLDAEFPKFRQLLPAEHTAVASADVAELTEAIKLVALVADRGAQ-VRMEFADGMLRL 316
Query: 293 TANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLT 341
+A + AEE + V ++G + I FN +Y++D L +L E V T
Sbjct: 317 SAGADDVGRAEEDIAVEFAGQPLTIAFNPTYLIDGLASLHSERVSFGFT 365
>2AVT-A nrPDB
Length = 378
Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 82/347 (23%), Positives = 170/347 (48%), Gaps = 9/347 (2%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
++F++ R + L + + +PIL ++ ++V ++LTG++ ++ + + +
Sbjct: 2 IQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVS 61
Query: 61 QPH------EPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAA 114
+ PGA + A F +I LP+ + ++E ++++ SG+S +L
Sbjct: 62 NENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVD 121
Query: 115 DFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGM-LFETEGEELRTVATD 173
+P L + +E L +K +I T F+ + Q+ R L G+ + + ++ + VATD
Sbjct: 122 QYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATD 181
Query: 174 GHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233
HR++ + + + V++P K + E + + V + I F
Sbjct: 182 SHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFY 241
Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKI 292
++L++G +PD R+L + + L+ A RA ++SN G V+L +++N +
Sbjct: 242 TRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISA 301
Query: 293 TANNPEQEEAEEILD-VTYSGAEMEIGFNVSYVLDVLNALKCENVRM 338
N+PE + E LD V+ SG+++ I FN +Y+++ L A+K E V++
Sbjct: 302 HVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKI 348
>2AWA-A nrPDB
Length = 390
Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 79/353 (22%), Positives = 172/353 (48%), Gaps = 13/353 (3%)
Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQP 62
F++ + L+ L + + +PIL + + V + ++L G++ ++ + ++ Q
Sbjct: 16 FSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFIS--QK 73
Query: 63 HEP--------GATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAA 114
+E G+ + A F ++ LP+ ++E ++++ SG+S +L +
Sbjct: 74 NEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSE 133
Query: 115 DFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFE-TEGEELRTVATD 173
+P + + + L +K++I T F+ + Q+ R L G+ F ++ +EL+TVATD
Sbjct: 134 QYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATD 193
Query: 174 GHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233
HRL+ + + ++ V++P + + E + + + +N I + F
Sbjct: 194 SHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFY 253
Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKI 292
++L++G +PD R++P + + + L+Q+ RA +LS+ G V+L + + +
Sbjct: 254 TRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSA 313
Query: 293 TANNPEQEEAEEILDV-TYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSV 344
++PE + E +D +G ++ I FN +Y++D L AL E V + +V
Sbjct: 314 HVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAV 366
>3T0P-A nrPDB
Length = 371
Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 85/369 (23%), Positives = 172/369 (46%), Gaps = 7/369 (1%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK + +LLK + VS + R T+ IL +L+ + + L D+E+ + +
Sbjct: 2 MKLICSKANLLKGVNIVSKAVPTRTTMAILECILIDASANEIKLMANDMELG-IETIIDG 60
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE-RMLVRSGRSRFSLSTLPAADFPNL 119
E G + A+ F +I R LP+ ++ ++ + + ++ +++F++ DF +
Sbjct: 61 TIEERGIIALDAKIFSEIVRKLPDN-DVTIETDASFKTVISCEKAKFNIIGKSGDDFSYI 119
Query: 120 DDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAV 179
+ L Q T+K +I T FS+A D + G LFE E +LR V+ DGHR+++
Sbjct: 120 PYVERNESIVLSQFTLKEVIRQTIFSIADNDNNKLMTGELFEIEENKLRVVSLDGHRISI 179
Query: 180 CSMPIGQSLPSHSVIVPRKGVIELMRMLDG-GDNPLRVQIGSNNIRAHVGDFIFTSKLVD 238
+ + S V+VP K + E+ +++ G D + + I +N+I + S+L++
Sbjct: 180 RYIEMKNHYDSKKVVVPGKTLQEISKIIPGSADEDVVIYITNNHIVFEFENTTVVSRLIE 239
Query: 239 GRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNP 297
G + ++L + D + L RA +L E + + + +++ +++ N+
Sbjct: 240 GEYFKIDQMLSSDYDTKVRINKRELLDCIDRATLLVKEGDKKPIIMNITDGNMELRINSF 299
Query: 298 EQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSA 357
E+I M IGFN + +D L + E V + + + + I+D +
Sbjct: 300 IGSMNEDIDIDKDGKDIM-IGFNPKFFIDALRVIDEEEVNLYMVNPKAPCFIKDDEGK-F 357
Query: 358 AYVVMPMRL 366
Y+++P+
Sbjct: 358 IYLILPVNF 366
>6DJ8-A nrPDB
Length = 393
Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 76/385 (19%), Positives = 163/385 (42%), Gaps = 28/385 (7%)
Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQP 62
F E ++ +++ G + R I LL++V L + TD + + +++V
Sbjct: 15 FICETNQIMNEIEKAKGIILNRNMNDIWSALLIEVKKSNLIIKSTDRNIFFESTISIVSE 74
Query: 63 HEPGATTVPARKFFDICRGLPEGAEIAVQL---------------EGERMLVRSGRSRFS 107
+ + A F+D + +I + E E FS
Sbjct: 75 TD-FKVLINASNFYDAVKAFNFYKKIKIVFNENNSKLEIMGELNDEKEEYEDHLKEPTFS 133
Query: 108 LSTLPAADFPNLD-DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF-ETEGE 165
+ ++ ++ D+ +E + Q + K++I FS + + LNG+ F + E
Sbjct: 134 YEEIENYNYDMVNEDYTFGIE--IKQKSFKKVINRIAFSAHLDESKNVLNGVYFSKDEDS 191
Query: 166 ELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRA 225
+L V+T+GHR+++C + + IVP K + ++ L G+ ++++
Sbjct: 192 KLLLVSTNGHRMSICKTEVIVE-EDVNFIVPVK-IFNFLKHLMSGEGMVKIKFSDKKFYV 249
Query: 226 HVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYV 285
++ L++G +PDY+ ++PK +LK AR + +K R + L
Sbjct: 250 EFDNYKIACSLINGNYPDYKSIIPKEQKNKSLVSLGILKDRLARVNLYV-DKSRKLVLTF 308
Query: 286 SENQLKITANNPEQEEAEEIL----DVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLT 341
SE QLK+ + E + Y GA+ + N+SY ++ ++ + + +
Sbjct: 309 SELQLKLLGEDLITGRKGEFFIKDPNYLYDGADEVMAINISYFVEAISVFETSKIEIQF- 367
Query: 342 DSVSSVQIEDAASQSAAYVVMPMRL 366
+S + +++ + + + +++MPM L
Sbjct: 368 NSGNVLKLSEPENFNFTHLIMPMSL 392
>4S3I-A nrPDB
Length = 384
Score = 81.3 bits (199), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 79/349 (22%), Positives = 156/349 (44%), Gaps = 35/349 (10%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK +V + L L+ + L + I ++ L+V L L +D ++ + + +
Sbjct: 3 MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSDIGLKSYIFTQ 62
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ G T+ +KF DI L + + I ++ + + + ++ +S F L A +FP
Sbjct: 63 SSDKEGVGTINGKKFLDIISCLKD-SNIILETKDDSLAIKQNKSSFKLPMFDADEFPEFP 121
Query: 121 --DWQSEVEFTLP--QATMKRL---IEATQFSMAHQDVRYYLNGML--FETEGEELRTVA 171
D + +E P K++ IE T +H + L G+L F+ + + L V
Sbjct: 122 VIDPKVSIEVNAPFLVDAFKKIAPVIEQT----SH---KRELAGILMQFDQKHQTLSVVG 174
Query: 172 TDGHRLAVCSM---PIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVG 228
TD RL+ + I + S I+P++ ++E++++ S+ + A +
Sbjct: 175 TDTKRLSYTQLEKISIHSTEEDISCILPKRALLEILKLFYEN-----FSFKSDGMLAVIE 229
Query: 229 D--FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVS 286
+ F +KL+DG +PDY+++LPK G + K++ + LS+ ++L +
Sbjct: 230 NEMHTFFTKLIDGNYPDYQKILPKEYISSFTLGKEEFKESIKLCSSLSS----TIKLTLE 285
Query: 287 ENQLKITANNPEQEEAEEILDVTYSGAEME----IGFNVSYVLDVLNAL 331
+N + + E E + G ++E +G N + L+ LNAL
Sbjct: 286 KNNALFESLDSEHSETAKTSVEIEKGLDIEKAFHLGVNAKFFLEALNAL 334
>5Y86-A nrPDB
Length = 588
Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 10/112 (8%)
Query: 21 LGGRPTLPI----LGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPAR-KF 75
LG R + PI G +L ++ G G D ++ + L+ P R K+
Sbjct: 382 LGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKY 441
Query: 76 FDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVE 127
F +G+P + Q +G +LV GRSR P P DW + ++
Sbjct: 442 FINSKGIPRYCSVTTQADGRVVLV-GGRSRRGKKRGP----PGSKDWGTALK 488
>3HPX-A nrPDB
Length = 425
Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 40/144 (27%), Positives = 58/144 (40%), Gaps = 23/144 (15%)
Query: 25 PTLPILGNLLLQVADGTLSLTGTDLEM---EMVARVALV---QPHEPGATTVPARKFFDI 78
P PI+ NL V T ++ +E + R +++ PH T V A +
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAEL--- 299
Query: 79 CRGLPEGA---EIAVQLEGER----MLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLP 131
G GA E + GER LV G + FS P DF N+D+ + VE+
Sbjct: 300 --GFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQ 357
Query: 132 QATMKRL-----IEATQFSMAHQD 150
+R + T FS +HQD
Sbjct: 358 LPVHERHPYGGDLVYTAFSGSHQD 381
>3MWB-A nrPDB
Length = 313
Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 25/156 (16%)
Query: 163 EGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI---- 218
E +++ ++T GH A C + + + LP+ + M +L+ D P I
Sbjct: 101 ELSDIKRISTHGHAWAQCRLWVDEHLPNADYVPGSSTAASAMGLLE-DDAPYEAAICAPL 159
Query: 219 ------GSNNIRAHVGD-------FIFTSKLVDGRFP-----DYRRVLPKNPDKHLEAGC 260
G N + +GD FI S+ G P D V+ P+ H A
Sbjct: 160 IAAEQPGLNVLAEDIGDNPDAVTRFILVSR--PGALPERTGADKTTVVVPLPEDHPGALM 217
Query: 261 DLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296
++L Q +R LS + R Y+ I A+
Sbjct: 218 EILDQFASRGVNLSRIESRPTGQYLGHYFFSIDADG 253
>3HQ1-A nrPDB
Length = 644
Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 40/144 (27%), Positives = 58/144 (40%), Gaps = 23/144 (15%)
Query: 25 PTLPILGNLLLQVADGTLSLTGTDLEM---EMVARVALV---QPHEPGATTVPARKFFDI 78
P PI+ NL V T ++ +E + R +++ PH T V A +
Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAEL--- 299
Query: 79 CRGLPEGA---EIAVQLEGERM----LVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLP 131
G GA E + GER LV G + FS P DF N+D+ + VE+
Sbjct: 300 --GFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQ 357
Query: 132 QATMKRL-----IEATQFSMAHQD 150
+R + T FS +HQD
Sbjct: 358 LPVHERHPYGGDLVYTAFSGSHQD 381
>4EWP-A nrPDB
Length = 350
Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 15/92 (16%)
Query: 26 TLPILGNLLLQVADGTLSLTGTDLEMEMVARV---------ALVQPHEPGATTVPARKFF 76
T+P++ + A L G+DL+ +V+ V A + HE GAT PA
Sbjct: 61 TVPVMAVGAAREALERAGLQGSDLDAVIVSTVTFPHATPSAAALVAHEIGATPAPAYDVS 120
Query: 77 DICRGLPEGAEIAVQLEGERMLVRSGRSRFSL 108
C G G A LVRSG +R L
Sbjct: 121 AACAGYCYGVAQA------DALVRSGTARHVL 146
>3BH7-B nrPDB
Length = 352
Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 23/128 (17%)
Query: 191 HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPK 250
+++ RK + E++ G VQ +++A +F K PD+ +L K
Sbjct: 247 YTIANARKLIDEMV-----GKGFFLVQTKEVSMKAEDAQRVFREKA-----PDFLPLLNK 296
Query: 251 NPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTY 310
P LE D A ++ NE F G +++VSE+ +E A +D Y
Sbjct: 297 GPVIALEFNGD---GAVEVCQLIVNEIFNGTKMFVSES----------KETASGDVDSFY 343
Query: 311 SGAEMEIG 318
+ A++++G
Sbjct: 344 NFADIQMG 351
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
6E8E-B nrPDB 465 e-131
5X06-A nrPDB 458 e-129
4TR8-A nrPDB 408 e-114
6DEG-A nrPDB 396 e-111
5WCE-A nrPDB 393 e-110
5W7Z-A nrPDB 381 e-106
6AP4-A nrPDB 377 e-105
6D46-A nrPDB 374 e-104
6MAN-A nrPDB 370 e-103
3P16-A nrPDB 367 e-102
5AH4-A nrPDB 365 e-101
6D47-A nrPDB 364 e-101
6E8D-A nrPDB 362 e-100
4TR6-A nrPDB 356 1e-98
1VPK-A nrPDB 344 3e-95
2AVT-A nrPDB 341 3e-94
2AWA-A nrPDB 341 3e-94
3T0P-A nrPDB 325 2e-89
4TRT-A nrPDB 315 2e-86
6DJ8-A nrPDB 292 2e-79
4S3I-A nrPDB 259 1e-69
Sequences not found previously or not previously below threshold:
3K4X-A nrPDB 52 5e-07
1AZW-A nrPDB 42 6e-04
5ZUT-A nrPDB 40 0.002
4L60-A nrPDB 38 0.006
1RXZ-A nrPDB 36 0.033
1V6S-A nrPDB 33 0.18
5XNX-A nrPDB 33 0.19
6G1M-A nrPDB 32 0.35
4NV8-A nrPDB 30 2.0
2BSZ-A nrPDB 30 2.0
2R5V-A nrPDB 30 2.4
3IBD-A nrPDB 29 2.9
5E58-A nrPDB 29 2.9
5E0E-A nrPDB 29 3.1
5A6D-A nrPDB 28 5.7
2IX2-C nrPDB 28 5.7
>6E8E-B nrPDB
Length = 517
Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats.
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV
Sbjct: 39 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 98
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD
Sbjct: 99 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 158
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC
Sbjct: 159 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 218
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240
SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR
Sbjct: 219 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 278
Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300
FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE
Sbjct: 279 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 338
Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360
EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV
Sbjct: 339 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 398
Query: 361 VMPMRL 366
VMPMRL
Sbjct: 399 VMPMRL 404
>5X06-A nrPDB
Length = 386
Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats.
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV
Sbjct: 21 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 80
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD
Sbjct: 81 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 140
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC
Sbjct: 141 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 200
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240
SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR
Sbjct: 201 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 260
Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300
FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE
Sbjct: 261 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 320
Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360
EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV
Sbjct: 321 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 380
Query: 361 VMPMRL 366
VMPMRL
Sbjct: 381 VMPMRL 386
Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats.
Identities = 24/128 (18%), Positives = 46/128 (35%), Gaps = 2/128 (1%)
Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLA 178
L S ++FT+ + + + ++ + + L +L + L TD
Sbjct: 14 LVPRGSHMKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEM 73
Query: 179 VCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIF-TSKLV 237
V + + Q + VP + ++ R L G + VQ+ + G F S L
Sbjct: 74 VARVALVQPHEPGATTVPARKFFDICRGLPEGAE-IAVQLEGERMLVRSGRSRFSLSTLP 132
Query: 238 DGRFPDYR 245
FP+
Sbjct: 133 AADFPNLD 140
>4TR8-A nrPDB
Length = 383
Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats.
Identities = 203/367 (55%), Positives = 264/367 (71%), Gaps = 1/367 (0%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
M FT++RE LLKPLQ V+G + R TLP+L N+LL V LSLTGTDLE+E+V RV L
Sbjct: 17 MHFTIQREALLKPLQLVAGVVERRQTLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLE 76
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
EPG TVPARK DIC+ LP I +++E +++LV++GRSRF+LSTLPA DFP ++
Sbjct: 77 DAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPTVE 136
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ + F++ Q+ ++RLI+ T F+MA QDVRYYLNGML E G LR+VATDGHRLA+C
Sbjct: 137 EGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMC 196
Query: 181 SMPIGQSLPS-HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDG 239
S+ H VIVPRKG++EL R+L D + + +G ++IRA G+F FTSKLVDG
Sbjct: 197 SLDAQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDG 256
Query: 240 RFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ 299
+FPDY RVLP+ DK + L++AF+R AILSNEK+RG+RL +S LKI ANNPEQ
Sbjct: 257 KFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNPEQ 316
Query: 300 EEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAY 359
EEAEE + V Y+G +EIGFNVSY+LDVL + E VR +L+DS SS + +A + +AY
Sbjct: 317 EEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDSAY 376
Query: 360 VVMPMRL 366
VVMPMRL
Sbjct: 377 VVMPMRL 383
>6DEG-A nrPDB
Length = 381
Score = 396 bits (1017), Expect = e-111, Method: Composition-based stats.
Identities = 141/374 (37%), Positives = 210/374 (56%), Gaps = 9/374 (2%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
M+ TV+R K L +V + R T+PIL N+L+ +G++ L TDL++E V V
Sbjct: 9 MRITVDRSQFFKSLGRVHRVVERRNTVPILSNVLIDAENGSVQLKATDLDLE-VTESFTV 67
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGER---MLVRSGRSRFSLSTLPAADFP 117
+ GA TVPA +DI R LP+G+EI + ++ + M + SG + F L LP DFP
Sbjct: 68 NIEKAGAITVPAYLLYDIVRKLPDGSEIVLSVDENQASAMSIVSGCTHFQLQCLPKIDFP 127
Query: 118 NLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGE---ELRTVATDG 174
Q F L + +K L++ TQF+++ ++ RYYLNG+ F + +LR VATDG
Sbjct: 128 ESLPGQFGCRFFLSASKLKHLLDCTQFAISTEETRYYLNGIYFHIVHDDVLKLRLVATDG 187
Query: 175 HRLAVCSMPIGQSLPS-HSVIVPRKGVIELMRMLDGG-DNPLRVQIGSNNIRAHVGDFIF 232
HRLA M + VI+PRK V EL ++L D + +++ IR +G +F
Sbjct: 188 HRLAQVDMEAPSGVDGMPGVIIPRKAVGELQKLLSEEIDGDVCIELSETKIRFSLGSVVF 247
Query: 233 TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKI 292
TSKLVDG FPDY+RV+P D+ L A R + +SN++ R V+L + QLK+
Sbjct: 248 TSKLVDGTFPDYQRVIPLGNDRKLIVNRQDFSSAVDRVSTISNDRGRAVKLTIEHGQLKL 307
Query: 293 TANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDA 352
NNP+ AE+ L TY+ +EIGFN Y+LD+ L + + ML+D+V+ I D
Sbjct: 308 VVNNPDSGSAEDQLAATYTSEPLEIGFNSRYLLDIAGQLSSDEMVFMLSDAVAPALIRDN 367
Query: 353 ASQSAAYVVMPMRL 366
+ YV+MP+R+
Sbjct: 368 NNAEVLYVLMPVRV 381
>5WCE-A nrPDB
Length = 379
Score = 393 bits (1010), Expect = e-110, Method: Composition-based stats.
Identities = 139/373 (37%), Positives = 205/373 (54%), Gaps = 8/373 (2%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK T+ER LLK L V + R T+PIL N+LL LS + TDL+ME++
Sbjct: 8 MKLTIERAALLKALGHVQSVVERRNTIPILSNILLSAEGDRLSFSATDLDMEIIDE-GFA 66
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE--RMLVRSGRSRFSLSTLPAADFPN 118
Q PG T PA ++I R LP+GA++++ G+ R+++++GRSRF+L LPA DFP
Sbjct: 67 QIDVPGQITAPAHTLYEIVRKLPDGADVSLSFSGDDPRLVIQAGRSRFNLPVLPAGDFPV 126
Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGE----ELRTVATDG 174
+ + + RLI+ T+F+++ ++ RYYLNG+ T E +LR VATDG
Sbjct: 127 MSSDGLSSRIAVDTNELIRLIDKTRFAISTEETRYYLNGLYVHTVNEGGETKLRAVATDG 186
Query: 175 HRLAVCSMPIGQ-SLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233
HRLA+ MP + ++ VIVPRK + E R+++ + +Q+ +R G T
Sbjct: 187 HRLALAEMPAPEGAVGIPGVIVPRKTIAEARRLMESAGETVDLQVSPQKVRFEFGAAALT 246
Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293
SK++DG FPDY RV+P++ K L DL +A R A +S EK R V+L V ++ +T
Sbjct: 247 SKVIDGAFPDYMRVIPRDNAKILTLDNDLFAKAVDRVATISAEKSRSVKLAVEPGRITLT 306
Query: 294 ANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAA 353
N E +A E ++V Y G EIGFN Y+LDV + D S + D
Sbjct: 307 VRNMEAGQAVEEVEVDYDGEPFEIGFNARYLLDVCGQIAGPQAEFRFADPASPTLVVDPV 366
Query: 354 SQSAAYVVMPMRL 366
YV+MP+R+
Sbjct: 367 DPGVKYVLMPLRV 379
Score = 35.0 bits (79), Expect = 0.057, Method: Composition-based stats.
Identities = 35/266 (13%), Positives = 81/266 (30%), Gaps = 28/266 (10%)
Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLA 178
+ ++ T+ +A + + + Q + ++ L+ +L EG+ L ATD
Sbjct: 1 MHHHHHHMKLTIERAALLKALGHVQSVVERRNTIPILSNILLSAEGDRLSFSATDLDMEI 60
Query: 179 VCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSN--NIRAHVGDFIFTSKL 236
+ +P + P + E++R L G + + + + G F +
Sbjct: 61 IDEGFAQIDVPG-QITAPAHTLYEIVRKLPDGA-DVSLSFSGDDPRLVIQAGRSRFNLPV 118
Query: 237 VD-GRFP-------------DYRRVLPKNPDKHLEAGCDLLKQAFA--RAAILSNEKFRG 280
+ G FP D ++ + + ++
Sbjct: 119 LPAGDFPVMSSDGLSSRIAVDTNELIRLIDKTRFAISTEETRYYLNGLYVHTVNEGGETK 178
Query: 281 VRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLN-----ALKCEN 335
+R ++ A P E A I V + +++ + +
Sbjct: 179 LRAVATDGHRLALAEMPAPEGAVGIPGVIVPRKTIA---EARRLMESAGETVDLQVSPQK 235
Query: 336 VRMMLTDSVSSVQIEDAASQSAAYVV 361
VR + + ++ D A V+
Sbjct: 236 VRFEFGAAALTSKVIDGAFPDYMRVI 261
>5W7Z-A nrPDB
Length = 387
Score = 381 bits (979), Expect = e-106, Method: Composition-based stats.
Identities = 106/379 (27%), Positives = 193/379 (50%), Gaps = 14/379 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+K VE + L++ L S + R +P N+ L DG L L+ T++++ + ++A V
Sbjct: 10 LKLIVETKTLVQSLGFASSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
Q G TV + DI R LP+ L + ++ +F+L TLP + FP +D
Sbjct: 69 QVVSEGECTVSTKTLNDIVRKLPDSELTLTDLGTTGLEIKGKNCKFNLFTLPVSSFPAMD 128
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
E F + ++IE+T+FS++ + RY LNG+ + +E + +TDGHRL++
Sbjct: 129 SINPEASFKISCTDFAKIIESTKFSISLDETRYNLNGVYLHIKDKEFCSASTDGHRLSIS 188
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGD---NPLRVQIGSNNIRAHVG-DFIFTSKL 236
+ + + + + VI+P+K E+++++ + + + SN I+ + SKL
Sbjct: 189 WVTLEKQIKNFGVILPQKSAEEILKIVKDPKNINEDIEILLSSNKIKFICNENTSMLSKL 248
Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296
+DG FPDY +P++ L + + R AI++ EKFR V+L +S L+I+A
Sbjct: 249 IDGTFPDYSTFIPESSSSKLVINRKMFADSIERIAIITVEKFRAVKLSLSRETLEISAVG 308
Query: 297 PEQEEAEEILDVTYSG---------AEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347
+ A+E+++ + + IGFN Y+ DVL A+K + V + +D + V
Sbjct: 309 EARGNAKEVINSSQDKESFYEYNSDESLAIGFNPQYLEDVLKAVKSDVVELYFSDVSAPV 368
Query: 348 QIEDAASQSAAYVVMPMRL 366
I+ + +VVMP+++
Sbjct: 369 LIKFPENPKDIFVVMPVKV 387
>6AP4-A nrPDB
Length = 388
Score = 377 bits (968), Expect = e-105, Method: Composition-based stats.
Identities = 169/382 (44%), Positives = 230/382 (60%), Gaps = 16/382 (4%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
M+ + +E LL L V G + R TL IL N+ +Q L++TG+DLE+E+VA AL
Sbjct: 7 MRLKIAKESLLNVLSHVVGAVERRHTLNILSNVKIQTNAQALTITGSDLEVELVASTALS 66
Query: 61 QPH--EPGATTVPARKFFDICRGLPEGAEIAVQL-EGERMLVRSGRSRFSLSTLPAADFP 117
+ E G TTVPARK +IC+ LP A I +Q+ E +R +++SG SRF L TLPA D+P
Sbjct: 67 EGACLEAGETTVPARKLMEICKSLPTAALIDLQITEDQRCILKSGNSRFVLGTLPAEDYP 126
Query: 118 NLDDWQS-EVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHR 176
L S + + Q +KRL E T F+MA QDVR+YL G L E + +LR V TDGHR
Sbjct: 127 LLTTENSQGTQVQVTQRELKRLFEKTAFAMAVQDVRFYLTGTLLEIDENQLRAVTTDGHR 186
Query: 177 LAVCSMPIGQSLPS-HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD------ 229
LA+C + + IVPRK V EL R+L D L + IG + +
Sbjct: 187 LALCEILASSTSSQLVQAIVPRKAVGELQRLLSIEDEQLTLLIGRELLNVTINTPSRDKE 246
Query: 230 -----FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLY 284
FT+KL+DG+FPDYRRV+P+ DKH+ G D+ KQ+ R AILSNEK RGV L
Sbjct: 247 QGDITVRFTTKLIDGKFPDYRRVIPRGGDKHVLIGHDVFKQSLQRVAILSNEKLRGVFLN 306
Query: 285 VSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSV 344
+++ L++ ANNPEQ+EA E L + Y A +E+ FN Y+LDVL L ++V M +T++
Sbjct: 307 FNQDSLQLRANNPEQDEAIEDLAIQYQSAPLEMSFNAQYLLDVLGVLDGDDVNMSMTEAN 366
Query: 345 SSVQIEDAASQSAAYVVMPMRL 366
SV ++D A YVVMPMR+
Sbjct: 367 QSVLVQDPAHPDQTYVVMPMRV 388
>6D46-A nrPDB
Length = 389
Score = 374 bits (960), Expect = e-104, Method: Composition-based stats.
Identities = 108/381 (28%), Positives = 197/381 (51%), Gaps = 16/381 (4%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+K VE + L++ L + R +P N+ L DG L L+ T++++ + ++A V
Sbjct: 10 LKLIVETKTLVQSLGFARSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
Q G TV + DI R LP+ +L+ ++ ++ +F+L TLP + FP +D
Sbjct: 69 QVLSEGEITVSTQTLSDIVRKLPDSELTLTELDIMKLEIKGQNCQFNLFTLPVSSFPAMD 128
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ EV F + A ++IE+T+FS++ + RY LNG+ + +E +TDGHRL++
Sbjct: 129 SIKPEVSFKISCADFAKIIESTKFSISLDETRYNLNGIYLHIKDKEFFAASTDGHRLSIS 188
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGD---NPLRVQIGSNNIRAHVG-DFIFTSKL 236
+ + + + + VI+P+K E+++++ + + + SN I+ + I SKL
Sbjct: 189 WITLEEKIKNFGVILPQKSAEEILKIVKDLKNIHEDIEILLSSNKIKFICNENTILLSKL 248
Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296
+DG FPDY +PK+ L + + R AI++ EKFR ++L +S L+I+A
Sbjct: 249 IDGTFPDYSAFIPKSSISKLVINRKIFADSIERIAIITVEKFRAIKLSLSRKTLEISAVG 308
Query: 297 PEQEEAEEILDVTYSG---------AEMEIGFNVSYVLDVLNALKCENVRMMLTD--SVS 345
+ A+EI+ + + IGFN Y+ DVL A+K V + +D + +
Sbjct: 309 EARGNAKEIITASQDKESFYEYNCDESLVIGFNPQYLEDVLKAVKSNLVELYFSDISASA 368
Query: 346 SVQIEDAASQSAAYVVMPMRL 366
V I+ + +V+MP+++
Sbjct: 369 PVLIKFPQNPKDIFVIMPVKV 389
>6MAN-A nrPDB
Length = 387
Score = 370 bits (950), Expect = e-103, Method: Composition-based stats.
Identities = 114/379 (30%), Positives = 193/379 (50%), Gaps = 14/379 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+K VE + L++ L S + R + L N+ L DG L L+ T++++ + ++ V
Sbjct: 10 LKVIVETKTLVQALGFASSVVEKRNIISELANIKLLAKDGLLELSSTNMDLYLSQKIG-V 68
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
Q G TV + DI + LP+ L + + RF+L TLP FP +D
Sbjct: 69 QVVSEGELTVSTKTLNDIVKKLPDSELTLTDLGTTGLEITGKNCRFNLFTLPVESFPVMD 128
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ E F + A ++IE+T+FS++ + RY LNG+ + E +TDGHRL+V
Sbjct: 129 NINPEASFKISCAEFAKIIESTKFSVSLDETRYNLNGIYLHVKDSEFYAASTDGHRLSVS 188
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDN---PLRVQIGSNNIRAHVG-DFIFTSKL 236
S+ + + + VI+P+K E+++++ N + + + SN I+ + I SKL
Sbjct: 189 SVVLAEKIEDFGVILPQKSAEEILKIVKDSKNANADIEILLSSNKIKFICNENVIMLSKL 248
Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296
+DG FPDY +P+N L + R AI++ EKFR V+L +S L+I+A
Sbjct: 249 IDGTFPDYSSFIPENSSSKLVINRKIFADTIERIAIITVEKFRAVKLSLSGEALEISAIG 308
Query: 297 PEQEEAEEILD--------VTYSGA-EMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347
+ A+E+++ YSG ++IGFN Y+ DVL A+K + V + + + V
Sbjct: 309 EARGNAKEVINSSKETENFYEYSGETNLDIGFNPQYLEDVLKAIKSDLVELYFSSVSAPV 368
Query: 348 QIEDAASQSAAYVVMPMRL 366
I+ S +VVMP+++
Sbjct: 369 LIKFPESPKDIFVVMPVKV 387
>3P16-A nrPDB
Length = 408
Score = 367 bits (941), Expect = e-102, Method: Composition-based stats.
Identities = 108/393 (27%), Positives = 177/393 (45%), Gaps = 32/393 (8%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+ F + RE + V+ L RP +P+L +LL +D L+++G D E+ A+V
Sbjct: 19 LTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVG-A 77
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ PG+ V R DI R LP + V +EG R+ + G +RFSL T+P D+P L
Sbjct: 78 EIVSPGSVLVSGRLLSDITRALPN-KPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLP 136
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
E LP I + D L G+ E GE + ATD RLAV
Sbjct: 137 TLPEETGL-LPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVR 195
Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGS------NNIRAHVGDFI- 231
+ S P +V+VP K + E + GG +R+ +G+ + + G+
Sbjct: 196 ELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGS-DVRLSLGTGPGVGKDGLLGISGNGKR 254
Query: 232 FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLK 291
T++L+D FP +R++LP L +A A++++ + VR+ ++ ++
Sbjct: 255 STTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQ-VRMEFADGSVR 313
Query: 292 ITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE- 350
++A + AEE L V Y+G + I FN +Y+ D L++L+ E V T + +
Sbjct: 314 LSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRP 373
Query: 351 -----------------DAASQSAAYVVMPMRL 366
A S Y++MP+RL
Sbjct: 374 VSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRL 406
>5AH4-A nrPDB
Length = 401
Score = 365 bits (938), Expect = e-101, Method: Composition-based stats.
Identities = 107/390 (27%), Positives = 170/390 (43%), Gaps = 29/390 (7%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+KF V RE + V+ L RPT+P+L +LL D L+++G D E+ +V+
Sbjct: 15 LKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVS-A 73
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ G+ V R DI + LP + V +EG R+ + G +RFSL TL D+P L
Sbjct: 74 EIASAGSVLVSGRLLSDITKALP-AKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALP 132
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
E + I + D L G+ E GE + ATD RLAV
Sbjct: 133 ALPEETGV-IASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVR 191
Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIF------ 232
+ + +V+VP K + E + G N + + +GS G
Sbjct: 192 ELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDG-NQVHLALGSGASVGKDGLLGIRSEGKR 250
Query: 233 -TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLK 291
T++L+D FP +R++LP G L +A R A++++ + +R+ S++ LK
Sbjct: 251 STTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQ-IRMEFSDDTLK 309
Query: 292 ITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE- 350
++A + AEE L V ++G + I FN +Y+ D L +L E V T +
Sbjct: 310 LSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRP 369
Query: 351 --------------DAASQSAAYVVMPMRL 366
AA Y++MP+RL
Sbjct: 370 AGEDDGANGGSGPFPAAKTDYVYLLMPVRL 399
>6D47-A nrPDB
Length = 410
Score = 364 bits (935), Expect = e-101, Method: Composition-based stats.
Identities = 103/392 (26%), Positives = 171/392 (43%), Gaps = 30/392 (7%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
+KF + RE + V+ L RP +P+L +LL +D L+++G D E+ RV
Sbjct: 21 LKFRLVRESFADAVSWVAKNLPTRPAVPVLSGVLLTGSDEGLTISGFDYEVSAEVRVP-A 79
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ PG V R DI R LP + ++G R+ + G +RFSL T+ D+P L
Sbjct: 80 EIASPGTVLVSGRLLSDITRALPN-KPVDFYVDGNRVALTCGNARFSLPTMAVEDYPTLP 138
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ TLP I + D L G+ E GE++ ATD RLAV
Sbjct: 139 TLPEDTG-TLPAELFSEAIGQVAIAAGRDDTLPMLTGIRVEISGEKVVLAATDRFRLAVR 197
Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNP-----LRVQIGSNNIRAHVGDFI-F 232
+ P +V+VP K + E + G + +G + + GD
Sbjct: 198 ELTWNALSPDIEAAVLVPAKTLGEAAKANTDGSEVRLSLGAGMGVGKDGLLGISGDGKRS 257
Query: 233 TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKI 292
T++L+D FP +R++LP A L +A A++++ + VR+ ++ L++
Sbjct: 258 TTRLLDAEFPKFRQLLPAEHTAVASADVAELTEAIKLVALVADRGAQ-VRMEFADGMLRL 316
Query: 293 TANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDA 352
+A + AEE + V ++G + I FN +Y++D L +L E V T + A
Sbjct: 317 SAGADDVGRAEEDIAVEFAGQPLTIAFNPTYLIDGLASLHSERVSFGFTTPGKPALLRPA 376
Query: 353 AS------------------QSAAYVVMPMRL 366
++ Y++MP+RL
Sbjct: 377 SAEDRIVSGPGDQGPFAAVPTDYVYLLMPVRL 408
>6E8D-A nrPDB
Length = 512
Score = 362 bits (929), Expect = e-100, Method: Composition-based stats.
Identities = 99/377 (26%), Positives = 198/377 (52%), Gaps = 13/377 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVA-- 58
MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + +
Sbjct: 39 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 98
Query: 59 -----LVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112
+V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L
Sbjct: 99 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 157
Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172
A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT
Sbjct: 158 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 217
Query: 173 DGHRLAVCSMPIGQSLP-SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFI 231
D HRLA+ + S++V++P K + EL ++LD + + I + + +
Sbjct: 218 DSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKNVL 277
Query: 232 FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE--NQ 289
F S+L+DG +PD ++P++ + QA RA++L+ E V ++
Sbjct: 278 FFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPAES 337
Query: 290 LKITANNPEQEEAEE-ILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQ 348
++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++
Sbjct: 338 IEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRPFL 397
Query: 349 IEDAASQSAAYVVMPMR 365
I ++ +++P+R
Sbjct: 398 IRTPNDETIVQLILPVR 414
>4TR6-A nrPDB
Length = 380
Score = 356 bits (913), Expect = 1e-98, Method: Composition-based stats.
Identities = 99/377 (26%), Positives = 198/377 (52%), Gaps = 13/377 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVA-- 58
MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + +
Sbjct: 3 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 62
Query: 59 -----LVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112
+V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L
Sbjct: 63 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 121
Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172
A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT
Sbjct: 122 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 181
Query: 173 DGHRLAVCSMPIGQSLP-SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFI 231
D HRLA+ + S++V++P K + EL ++LD + + I + + +
Sbjct: 182 DSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKNVL 241
Query: 232 FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE--NQ 289
F S+L+DG +PD ++P++ + QA RA++L+ E V ++
Sbjct: 242 FFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPAES 301
Query: 290 LKITANNPEQEEAEE-ILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQ 348
++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++
Sbjct: 302 IEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRPFL 361
Query: 349 IEDAASQSAAYVVMPMR 365
I ++ +++P+R
Sbjct: 362 IRTPNDETIVQLILPVR 378
>1VPK-A nrPDB
Length = 378
Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats.
Identities = 99/367 (26%), Positives = 175/367 (47%), Gaps = 3/367 (0%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK TV L + S L + PIL L +V DG + TDLE + A V
Sbjct: 13 MKVTVTTLELKDKITIASKALAKKSVKPILAGFLFEVKDGNFYICATDLETGVKATVNAA 72
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ VP + + LP+ + LEG+ +++ SG + F ++T+PA +FP +
Sbjct: 73 EISGEARFVVPGDVIQKMVKVLPD-EITELSLEGDALVISSGSTVFRITTMPADEFPEIT 131
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+S + F + + ++ ++E F+ A + LNG+ +E LR VA+DG RLA+
Sbjct: 132 PAESGITFEVDTSLLEEMVEKVIFAAAKDEFMRNLNGVFWELHKNLLRLVASDGFRLALA 191
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNP-LRVQIGSNNIRAHVGDFIFTSKLVDG 239
I S ++ K + E+ +LD P + V+ + D ++VD
Sbjct: 192 EEQIENEEE-ASFLLSLKSMKEVQNVLDNTTEPTITVRYDGRRVSLSTNDVETVMRVVDA 250
Query: 240 RFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ 299
FPDY+RV+P+ + L+++ R +++++ V+ + EN +++ + +P+
Sbjct: 251 EFPDYKRVIPETFKTKVVVSRKELRESLKRVMVIASKGSESVKFEIEENVMRLVSKSPDY 310
Query: 300 EEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAY 359
E + ++V G ++ I FN ++ DVL ++ E + M DS S QI Y
Sbjct: 311 GEVVDEVEVQKEGEDLVIAFNPKFIEDVLKHIETEEIEMNFVDSTSPCQINPLDISGYLY 370
Query: 360 VVMPMRL 366
+VMP+RL
Sbjct: 371 IVMPIRL 377
>2AVT-A nrPDB
Length = 378
Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats.
Identities = 86/375 (22%), Positives = 177/375 (47%), Gaps = 10/375 (2%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
++F++ R + L + + +PIL ++ ++V ++LTG++ ++ + + +
Sbjct: 2 IQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVS 61
Query: 61 Q------PHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAA 114
PGA + A F +I LP+ + ++E ++++ SG+S +L
Sbjct: 62 NENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVD 121
Query: 115 DFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGML-FETEGEELRTVATD 173
+P L + +E L +K +I T F+ + Q+ R L G+ + ++ + VATD
Sbjct: 122 QYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATD 181
Query: 174 GHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233
HR++ + + + V++P K + E + + V + I F
Sbjct: 182 SHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFY 241
Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKI 292
++L++G +PD R+L + + L+ A RA ++SN G V+L +++N +
Sbjct: 242 TRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISA 301
Query: 293 TANNPEQEEAEEILD-VTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIED 351
N+PE + E LD V+ SG+++ I FN +Y+++ L A+K E V++ V +
Sbjct: 302 HVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTP 361
Query: 352 -AASQSAAYVVMPMR 365
+S ++ P+R
Sbjct: 362 GDEEESFIQLITPVR 376
>2AWA-A nrPDB
Length = 390
Score = 341 bits (874), Expect = 3e-94, Method: Composition-based stats.
Identities = 80/373 (21%), Positives = 176/373 (47%), Gaps = 10/373 (2%)
Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQ- 61
F++ + L+ L + + +PIL + + V + ++L G++ ++ + ++
Sbjct: 16 FSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNE 75
Query: 62 -----PHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADF 116
G+ + A F ++ LP+ ++E ++++ SG+S +L + +
Sbjct: 76 DAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQY 135
Query: 117 PNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFET-EGEELRTVATDGH 175
P + + + L +K++I T F+ + Q+ R L G+ F + +EL+TVATD H
Sbjct: 136 PRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSH 195
Query: 176 RLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSK 235
RL+ + + ++ V++P + + E + + + +N I + F ++
Sbjct: 196 RLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTR 255
Query: 236 LVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITA 294
L++G +PD R++P + + + L+Q+ RA +LS+ G V+L + + +
Sbjct: 256 LLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHV 315
Query: 295 NNPEQEEAEEILDVTY-SGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAA 353
++PE + E +D +G ++ I FN +Y++D L AL E V + +V + A
Sbjct: 316 HSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPAD 375
Query: 354 -SQSAAYVVMPMR 365
+ ++ P+R
Sbjct: 376 TDEDFMQLITPVR 388
>3T0P-A nrPDB
Length = 371
Score = 325 bits (832), Expect = 2e-89, Method: Composition-based stats.
Identities = 85/369 (23%), Positives = 171/369 (46%), Gaps = 7/369 (1%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK + +LLK + VS + R T+ IL +L+ + + L D+E+ + +
Sbjct: 2 MKLICSKANLLKGVNIVSKAVPTRTTMAILECILIDASANEIKLMANDMELGIE-TIIDG 60
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE-RMLVRSGRSRFSLSTLPAADFPNL 119
E G + A+ F +I R LP+ ++ ++ + + ++ +++F++ DF +
Sbjct: 61 TIEERGIIALDAKIFSEIVRKLPDN-DVTIETDASFKTVISCEKAKFNIIGKSGDDFSYI 119
Query: 120 DDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAV 179
+ L Q T+K +I T FS+A D + G LFE E +LR V+ DGHR+++
Sbjct: 120 PYVERNESIVLSQFTLKEVIRQTIFSIADNDNNKLMTGELFEIEENKLRVVSLDGHRISI 179
Query: 180 CSMPIGQSLPSHSVIVPRKGVIELMRMLDG-GDNPLRVQIGSNNIRAHVGDFIFTSKLVD 238
+ + S V+VP K + E+ +++ G D + + I +N+I + S+L++
Sbjct: 180 RYIEMKNHYDSKKVVVPGKTLQEISKIIPGSADEDVVIYITNNHIVFEFENTTVVSRLIE 239
Query: 239 GRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNP 297
G + ++L + D + L RA +L E + + + +++ +++ N+
Sbjct: 240 GEYFKIDQMLSSDYDTKVRINKRELLDCIDRATLLVKEGDKKPIIMNITDGNMELRINSF 299
Query: 298 EQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSA 357
E+I M IGFN + +D L + E V + + + + I+D
Sbjct: 300 IGSMNEDIDIDKDGKDIM-IGFNPKFFIDALRVIDEEEVNLYMVNPKAPCFIKDDEG-KF 357
Query: 358 AYVVMPMRL 366
Y+++P+
Sbjct: 358 IYLILPVNF 366
>4TRT-A nrPDB
Length = 368
Score = 315 bits (806), Expect = 2e-86, Method: Composition-based stats.
Identities = 102/353 (28%), Positives = 175/353 (49%), Gaps = 12/353 (3%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK V ++ L + L + + R + P+L L ++ ++G L+L+GT+LE+++ V
Sbjct: 2 MKANVTKKTLNEGLGLLERVIPSRSSNPLLTALKVETSEGGLTLSGTNLEIDLSCFVP-A 60
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ +P VPA F I R L G + ++L G+ + VRSG S F L T +P L
Sbjct: 61 EVQQPENFVVPAHLFAQIVRNLG-GELVELELSGQELSVRSGGSDFKLQTGDIEAYPPL- 118
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180
+ ++ + +L + R + +++ +++ + G+ E GE R VA+DG+R+A+
Sbjct: 119 SFPAQADVSLDGGELSRAFSSVRYAASNEAFQAVFRGIKLEHHGESARVVASDGYRVAIR 178
Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240
P S ++I+P + V EL+R+L G+ R G + KL+DG
Sbjct: 179 DFP--ASGDGKNLIIPARSVDELIRVLKDGE--ARFTYGDGMLTVTTDRVKMNLKLLDGD 234
Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNPEQ 299
FPDY RV+PK+ + LK+A R A+L+++ V VSE L++ A +
Sbjct: 235 FPDYERVIPKDIKLQVTLPATALKEAVNRVAVLADKNANNRVEFLVSEGTLRLAAEG-DY 293
Query: 300 EEAEEILDVTYSGAE--MEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350
A++ L VT G E M + FN +VLD L + + ++ + S S
Sbjct: 294 GRAQDTLSVTQGGTEQAMSLAFNARHVLDALGPIDGD-AELLFSGSTSPAIFR 345
>6DJ8-A nrPDB
Length = 393
Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats.
Identities = 74/384 (19%), Positives = 160/384 (41%), Gaps = 26/384 (6%)
Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQP 62
F E ++ +++ G + R I LL++V L + TD + + +++V
Sbjct: 15 FICETNQIMNEIEKAKGIILNRNMNDIWSALLIEVKKSNLIIKSTDRNIFFESTISIVSE 74
Query: 63 HEPGATTVPARKFFDICRGLPEGAEIAVQL---------------EGERMLVRSGRSRFS 107
+ + A F+D + +I + E E FS
Sbjct: 75 TD-FKVLINASNFYDAVKAFNFYKKIKIVFNENNSKLEIMGELNDEKEEYEDHLKEPTFS 133
Query: 108 LSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF-ETEGEE 166
+ ++ +++ + Q + K++I FS + + LNG+ F + E +
Sbjct: 134 YEEIENYNYDMVNE-DYTFGIEIKQKSFKKVINRIAFSAHLDESKNVLNGVYFSKDEDSK 192
Query: 167 LRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAH 226
L V+T+GHR+++C + + IVP K + ++ L G+ ++++
Sbjct: 193 LLLVSTNGHRMSICKTEVIVE-EDVNFIVPVK-IFNFLKHLMSGEGMVKIKFSDKKFYVE 250
Query: 227 VGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVS 286
++ L++G +PDY+ ++PK +LK AR + + K R + L S
Sbjct: 251 FDNYKIACSLINGNYPDYKSIIPKEQKNKSLVSLGILKDRLARVNLYVD-KSRKLVLTFS 309
Query: 287 ENQLKITANNPEQEEAEEIL----DVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTD 342
E QLK+ + E + Y GA+ + N+SY ++ ++ + + + +
Sbjct: 310 ELQLKLLGEDLITGRKGEFFIKDPNYLYDGADEVMAINISYFVEAISVFETSKIEIQF-N 368
Query: 343 SVSSVQIEDAASQSAAYVVMPMRL 366
S + +++ + + + +++MPM L
Sbjct: 369 SGNVLKLSEPENFNFTHLIMPMSL 392
>4S3I-A nrPDB
Length = 384
Score = 259 bits (663), Expect = 1e-69, Method: Composition-based stats.
Identities = 77/384 (20%), Positives = 164/384 (42%), Gaps = 28/384 (7%)
Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60
MK +V + L L+ + L + I ++ L+V L L +D ++ + + +
Sbjct: 3 MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSDIGLKSYIFTQ 62
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120
+ G T+ +KF DI L + + I ++ + + + ++ +S F L A +FP
Sbjct: 63 SSDKEGVGTINGKKFLDIISCLKD-SNIILETKDDSLAIKQNKSSFKLPMFDADEFPEFP 121
Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGML--FETEGEELRTVATDGHRLA 178
+V + + + + + L G+L F+ + + L V TD RL+
Sbjct: 122 VIDPKVSIEVNAPFLVDAFKKIAPVIEQTSHKRELAGILMQFDQKHQTLSVVGTDTKRLS 181
Query: 179 VCSMP---IGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD--FIFT 233
+ I + S I+P++ ++E++++ S+ + A + + F
Sbjct: 182 YTQLEKISIHSTEEDISCILPKRALLEILKLFYEN-----FSFKSDGMLAVIENEMHTFF 236
Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293
+KL+DG +PDY+++LPK G + K++ + LS+ ++L + +N
Sbjct: 237 TKLIDGNYPDYQKILPKEYISSFTLGKEEFKESIKLCSSLSS----TIKLTLEKNNALFE 292
Query: 294 ANNPEQEEAEEILDVTYSGAEMEIGF----NVSYVLDVLNALKCENVRMMLTDSVSSVQI 349
+ + E E + G ++E F N + L+ LNAL + + S I
Sbjct: 293 SLDSEHSETAKTSVEIEKGLDIEKAFHLGVNAKFFLEALNALGTTQFVLRCNEPSSPFLI 352
Query: 350 EDAASQSAAY-------VVMPMRL 366
+++ + ++ ++MP+ L
Sbjct: 353 QESLDEKQSHLNAKISTLMMPITL 376
>3K4X-A nrPDB
Length = 798
Score = 51.6 bits (122), Expect = 5e-07, Method: Composition-based stats.
Identities = 58/398 (14%), Positives = 132/398 (33%), Gaps = 55/398 (13%)
Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVAD----GTLSLTGTDLEMEMVARVA 58
++ K ++ +S + + G++ + ++ME
Sbjct: 410 LSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPF-VDMEHPETSI 468
Query: 59 LVQPHEPGATTVPARKFFDICR--GLPEGAEIAVQLEGERM---LVRSGRSRFSLSTLPA 113
++ +P T A+ DI + L + I + E + ++SG +F L+
Sbjct: 469 KLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLA---- 524
Query: 114 ADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATD 173
P +D S + + A + EA+ F + + + F+ + + + A D
Sbjct: 525 ---PKFNDEGSNSQASNSGALEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVD 581
Query: 174 GHRLAVCSMPIGQSL-----PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIR 224
R+ + S+ IG H V + + L ++L G+N + + ++I
Sbjct: 582 DSRVLLVSLEIGVEAFQEYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSII 640
Query: 225 AHVGDFI------FTSKL--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE 276
D ++ KL +D F + D L + + LS+
Sbjct: 641 LLFEDTKKDRIAEYSLKLMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD- 696
Query: 277 KFRGVRLYVSENQLKITANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVL 325
+ + +++ +K A+ E E +++ F Y+L
Sbjct: 697 ---SINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLL 753
Query: 326 DVLNALK-CENVRMMLTDSVSSVQIEDAASQSAAYVVM 362
D++ + V + L+ S + + +
Sbjct: 754 DIIKGSSLSDRVGIRLS-SEAPALFQFDLKSGFLQFFL 790
Score = 51.6 bits (122), Expect = 6e-07, Method: Composition-based stats.
Identities = 58/398 (14%), Positives = 131/398 (32%), Gaps = 55/398 (13%)
Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVAD----GTLSLTGTDLEMEMVARVA 58
++ K ++ +S + + G++ + ++ME
Sbjct: 143 LSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPF-VDMEHPETSI 201
Query: 59 LVQPHEPGATTVPARKFFDICR--GLPEGAEIAVQLEGERM---LVRSGRSRFSLSTLPA 113
++ +P T A+ DI + L + I + E + ++SG +F L+
Sbjct: 202 KLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLA---- 257
Query: 114 ADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATD 173
P +D S + A + EA+ F + + + F+ + + + A D
Sbjct: 258 ---PKFNDEGSNSQSNGSGALEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVD 314
Query: 174 GHRLAVCSMPIGQSL-----PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIR 224
R+ + S+ IG H V + + L ++L G+N + + ++I
Sbjct: 315 DSRVLLVSLEIGVEAFQEYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSII 373
Query: 225 AHVGDFI------FTSKL--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE 276
D ++ KL +D F + D L + + LS+
Sbjct: 374 LLFEDTKKDRIAEYSLKLMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD- 429
Query: 277 KFRGVRLYVSENQLKITANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVL 325
+ + +++ +K A+ E E +++ F Y+L
Sbjct: 430 ---SINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLL 486
Query: 326 DVLNALK-CENVRMMLTDSVSSVQIEDAASQSAAYVVM 362
D++ + V + L+ S + + +
Sbjct: 487 DIIKGSSLSDRVGIRLS-SEAPALFQFDLKSGFLQFFL 523
Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats.
Identities = 37/261 (14%), Positives = 84/261 (32%), Gaps = 47/261 (18%)
Query: 131 PQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSL-- 188
+ KR+I + + + F+ + + + A D R+ + S+ IG
Sbjct: 14 EASLFKRII---------DGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQ 64
Query: 189 ---PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIRAHVGDFI------FTSK 235
H V + + L ++L G+N + + ++I D ++ K
Sbjct: 65 EYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLK 123
Query: 236 L--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293
L +D F + D L + + LS+ + + +++ +K
Sbjct: 124 LMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD----SINIMITKETIKFV 176
Query: 294 ANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVLDVLNALK-CENVRMMLT 341
A+ E E +++ F Y+LD++ + V + L+
Sbjct: 177 ADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLS 236
Query: 342 DSVSSVQIEDAASQSAAYVVM 362
S + + +
Sbjct: 237 -SEAPALFQFDLKSGFLQFFL 256
>1AZW-A nrPDB
Length = 313
Score = 41.5 bits (96), Expect = 6e-04, Method: Composition-based stats.
Identities = 21/97 (21%), Positives = 38/97 (39%), Gaps = 8/97 (8%)
Query: 143 QFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIE 202
+ A + Y++NG FE E + LR D HR+A +P + V+ P + +
Sbjct: 223 ALAFARIENHYFVNGGFFEVEDQLLR----DAHRIA--DIPGVIVHGRYDVVCPLQSAWD 276
Query: 203 LMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDG 239
L + L++ S + + + DG
Sbjct: 277 LHKAWP--KAQLQISPASGHSAFEPENVDALVRATDG 311
>5ZUT-A nrPDB
Length = 289
Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats.
Identities = 37/261 (14%), Positives = 84/261 (32%), Gaps = 47/261 (18%)
Query: 131 PQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSL-- 188
+ KR+I + + + F+ + + + A D R+ + S+ IG
Sbjct: 8 EASLFKRII---------DGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQ 58
Query: 189 ---PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIRAHVGDFI------FTSK 235
H V + + L ++L G+N + + ++I D ++ K
Sbjct: 59 EYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLK 117
Query: 236 L--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293
L +D F + D L + + LS+ + + +++ +K
Sbjct: 118 LMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD----SINIMITKETIKFV 170
Query: 294 ANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVLDVLNALK-CENVRMMLT 341
A+ E E +++ F Y+LD++ + V + L+
Sbjct: 171 ADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLS 230
Query: 342 DSVSSVQIEDAASQSAAYVVM 362
S + + +
Sbjct: 231 -SEAPALFQFDLKSGFLQFFL 250
>4L60-A nrPDB
Length = 256
Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats.
Identities = 37/261 (14%), Positives = 84/261 (32%), Gaps = 47/261 (18%)
Query: 131 PQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSL-- 188
+ KR+I + + + F+ + + + A D R+ + S+ IG
Sbjct: 8 EASLFKRII---------DGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQ 58
Query: 189 ---PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIRAHVGDFI------FTSK 235
H V + + L ++L G+N + + ++I D ++ K
Sbjct: 59 EYRCDHPVTL-GMDLTSLSKILRRGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLK 117
Query: 236 L--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293
L +D F + D L + + LS+ + + +++ +K
Sbjct: 118 LMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD----SINIMITKETIKFV 170
Query: 294 ANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVLDVLNALK-CENVRMMLT 341
A+ E E +++ F Y+LD++ + V + L+
Sbjct: 171 ADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLS 230
Query: 342 DSVSSVQIEDAASQSAAYVVM 362
S + + +
Sbjct: 231 -SEAPALFQFDLKSGFLQFFL 250
>1RXZ-A nrPDB
Length = 245
Score = 35.8 bits (81), Expect = 0.033, Method: Composition-based stats.
Identities = 18/122 (14%), Positives = 41/122 (33%), Gaps = 15/122 (12%)
Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGER-MLVRSGRSRFSLSTLPAADF--- 116
E V + FDI + + + + +E E + V+ G + ++ + +
Sbjct: 60 NIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKE 119
Query: 117 PNLDDWQSEVEFTLPQATMKRLI-------EATQFSMAHQDVRYYLNG----MLFETEGE 165
P + + + + + K+ I + F + R G ++F
Sbjct: 120 PRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTET 179
Query: 166 EL 167
EL
Sbjct: 180 EL 181
>1V6S-A nrPDB
Length = 390
Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats.
Identities = 25/140 (17%), Positives = 46/140 (32%), Gaps = 9/140 (6%)
Query: 111 LPAADFPNLDDWQSEVEFTLPQATMKR--LIEATQFSMAHQDVRYYLNGMLFETEGEELR 168
LP A F E L+E +F + L+ +
Sbjct: 81 LPEARFAPFPPGSEEARREAEALRPGEVLLLENVRFEPGEEKNDPELSARYARLGEAFVL 140
Query: 169 TVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVG 228
HR + + + LP+++ + K V L R+L + P V +G + +G
Sbjct: 141 DAFGSAHRAHASVVGVARLLPAYAGFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIG 200
Query: 229 DFIFTSKLVDGRFPDYRRVL 248
+++ P R+L
Sbjct: 201 -------VIESLLPRIDRLL 213
>5XNX-A nrPDB
Length = 394
Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats.
Identities = 27/114 (23%), Positives = 50/114 (43%), Gaps = 15/114 (13%)
Query: 165 EELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIR 224
E L +A HRL + S+ S +++ P+K E++R++ G + +R
Sbjct: 167 ETLEVIAPLAHRLGMASVKWELEDLSFAILHPKK-YEEIVRLVAGRAPSRDTYLA--KVR 223
Query: 225 AHVGDFIFTSKL---VDGRFPD-----YRRVLPKNP---DKHLEAGCDLLKQAF 267
A + + + SK+ V+GR P Y++++ K D H G +L
Sbjct: 224 AEIVNTLTASKIKATVEGR-PKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEI 276
>6G1M-A nrPDB
Length = 338
Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats.
Identities = 13/88 (14%), Positives = 33/88 (37%), Gaps = 1/88 (1%)
Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300
+PD ++ + + + I+S K + ++E + +P+
Sbjct: 57 YPDPITMVKQTDPDLVVIATNSFISVVKD-QIISILKENKNVITIAEEMAFPFSKDPKAA 115
Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVL 328
+ + ++ + + G N +VLD L
Sbjct: 116 NEIDTVAKDHNVSVLGTGVNPGFVLDTL 143
>4NV8-A nrPDB
Length = 312
Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats.
Identities = 14/96 (14%), Positives = 26/96 (27%), Gaps = 16/96 (16%)
Query: 116 FPNLDDWQSE---VEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172
F ++ + + L + + + + A D RY L G
Sbjct: 213 FDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLSIHHL------- 265
Query: 173 DGHRLAVCSMPIGQSLPS-----HSVIVPRKGVIEL 203
G R + L +I+P + E
Sbjct: 266 -GGRTEQTEIATAADLADTLQGLLGIIIPDRTAFEA 300
>2BSZ-A nrPDB
Length = 278
Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats.
Identities = 14/96 (14%), Positives = 26/96 (27%), Gaps = 16/96 (16%)
Query: 116 FPNLDDWQSE---VEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172
F ++ + + L + + + + A D RY L G
Sbjct: 179 FDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLSIHHL------- 231
Query: 173 DGHRLAVCSMPIGQSLPS-----HSVIVPRKGVIEL 203
G R + L +I+P + E
Sbjct: 232 -GGRTEQTEIATAADLADTLQGLLGIIIPDRTAFEA 266
>2R5V-A nrPDB
Length = 357
Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats.
Identities = 12/80 (15%), Positives = 27/80 (33%), Gaps = 4/80 (5%)
Query: 263 LKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ----EEAEEILDVTYSGAEMEIG 318
+Q F ++ + + + + +T P++ + +E L I
Sbjct: 184 FRQIFDEHIVVGAQAMNSTVVQSASGAVTLTLIEPDRNADPGQIDEFLKDHQGAGVQHIA 243
Query: 319 FNVSYVLDVLNALKCENVRM 338
FN + + + AL V
Sbjct: 244 FNSNDAVRAVKALSERGVEF 263
>3IBD-A nrPDB
Length = 476
Score = 29.2 bits (64), Expect = 2.9, Method: Composition-based stats.
Identities = 8/33 (24%), Positives = 11/33 (33%)
Query: 318 GFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350
FN + LD ALK + + E
Sbjct: 388 AFNPDHFLDANGALKKTEAFIPFSLGKRICLGE 420
>5E58-A nrPDB
Length = 493
Score = 29.2 bits (64), Expect = 2.9, Method: Composition-based stats.
Identities = 9/32 (28%), Positives = 11/32 (34%)
Query: 319 FNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350
FN + LD ALK M + E
Sbjct: 408 FNPDHFLDANGALKKSEAFMPFSIGKRICLGE 439
>5E0E-A nrPDB
Length = 463
Score = 29.2 bits (64), Expect = 3.1, Method: Composition-based stats.
Identities = 9/32 (28%), Positives = 11/32 (34%)
Query: 319 FNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350
FN + LD ALK M + E
Sbjct: 380 FNPDHFLDANGALKKSEAFMPFSIGKRICLGE 411
>5A6D-A nrPDB
Length = 249
Score = 28.4 bits (62), Expect = 5.7, Method: Composition-based stats.
Identities = 14/96 (14%), Positives = 40/96 (41%), Gaps = 11/96 (11%)
Query: 252 PDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYS 311
+ ++LK+A A+++S+ ++ E++ + A E ++
Sbjct: 130 FTAKVVLLGEVLKEAIKDASLVSD----SLKFIAKEDEFTMKAEGETNEVEIKLTLEDEG 185
Query: 312 GAEMEI------GFNVSYVLDVLNAL-KCENVRMML 340
++E+ + +SY+ D++ + K + V +
Sbjct: 186 LLDLEVEEETRSAYGISYLADMVKGIGKADEVTLRF 221
>2IX2-C nrPDB
Length = 259
Score = 28.4 bits (62), Expect = 5.7, Method: Composition-based stats.
Identities = 21/113 (18%), Positives = 41/113 (36%), Gaps = 10/113 (8%)
Query: 244 YRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ---- 299
+ R + K + +LK A L +E L ++ +++ A +
Sbjct: 7 FERNIRLINMKVVYDDVRVLKDIIQALARLVDEA----VLKFKQDSVELVALDRAHISLI 62
Query: 300 --EEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350
E+ E + GFN Y++ +L K + + ++S SV I
Sbjct: 63 SVNLPREMFKEYDVNDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIIN 115
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.310 0.138 0.328
Lambda K H
0.267 0.0427 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,617,679
Number of Sequences: 36641
Number of extensions: 413959
Number of successful extensions: 1452
Number of sequences better than 10.0: 42
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1238
Number of HSP's gapped (non-prelim): 82
length of query: 366
length of database: 10,336,785
effective HSP length: 98
effective length of query: 268
effective length of database: 6,745,967
effective search space: 1807919156
effective search space used: 1807919156
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 60 (27.7 bits)