BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0A988 (366 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6E8E-B nrPDB 754 0.0 5X06-A nrPDB 753 0.0 4TR8-A nrPDB 393 e-110 6AP4-A nrPDB 309 1e-84 5WCE-A nrPDB 249 1e-66 6DEG-A nrPDB 249 2e-66 6MAN-A nrPDB 187 7e-48 6D46-A nrPDB 184 5e-47 5W7Z-A nrPDB 182 2e-46 4TR6-A nrPDB 159 3e-39 6E8D-A nrPDB 158 3e-39 1VPK-A nrPDB 158 4e-39 4TRT-A nrPDB 137 7e-33 3P16-A nrPDB 132 2e-31 5AH4-A nrPDB 125 4e-29 6D47-A nrPDB 124 7e-29 2AVT-A nrPDB 123 1e-28 2AWA-A nrPDB 118 5e-27 3T0P-A nrPDB 106 2e-23 6DJ8-A nrPDB 89 3e-18 4S3I-A nrPDB 81 7e-16 5Y86-A nrPDB 30 1.9 3HPX-A nrPDB 30 2.0 3MWB-A nrPDB 29 2.8 3HQ1-A nrPDB 29 3.3 4EWP-A nrPDB 28 5.9 3BH7-B nrPDB 28 6.7 >6E8E-B nrPDB Length = 517 Score = 754 bits (1946), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/366 (100%), Positives = 366/366 (100%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV Sbjct: 39 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 98 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD Sbjct: 99 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 158 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC Sbjct: 159 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 218 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR Sbjct: 219 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 278 Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE Sbjct: 279 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 338 Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV Sbjct: 339 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 398 Query: 361 VMPMRL 366 VMPMRL Sbjct: 399 VMPMRL 404 >5X06-A nrPDB Length = 386 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/366 (100%), Positives = 366/366 (100%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV Sbjct: 21 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 80 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD Sbjct: 81 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 140 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC Sbjct: 141 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 200 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR Sbjct: 201 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 260 Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE Sbjct: 261 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 320 Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV Sbjct: 321 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 380 Query: 361 VMPMRL 366 VMPMRL Sbjct: 381 VMPMRL 386 >4TR8-A nrPDB Length = 383 Score = 393 bits (1009), Expect = e-110, Method: Compositional matrix adjust. Identities = 205/369 (55%), Positives = 267/369 (72%), Gaps = 5/369 (1%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 M FT++RE LLKPLQ V+G + R TLP+L N+LL V LSLTGTDLE+E+V RV L Sbjct: 17 MHFTIQREALLKPLQLVAGVVERRQTLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLE 76 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 EPG TVPARK DIC+ LP I +++E +++LV++GRSRF+LSTLPA DFP ++ Sbjct: 77 DAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPTVE 136 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + + F++ Q+ ++RLI+ T F+MA QDVRYYLNGML E G LR+VATDGHRLA+C Sbjct: 137 EGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMC 196 Query: 181 SMPIGQSLPS---HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLV 237 S+ +PS H VIVPRKG++EL R+L D + + +G ++IRA G+F FTSKLV Sbjct: 197 SLD--AQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLV 254 Query: 238 DGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNP 297 DG+FPDY RVLP+ DK + L++AF+R AILSNEK+RG+RL +S LKI ANNP Sbjct: 255 DGKFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNP 314 Query: 298 EQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSA 357 EQEEAEE + V Y+G +EIGFNVSY+LDVL + E VR +L+DS SS + +A + + Sbjct: 315 EQEEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDS 374 Query: 358 AYVVMPMRL 366 AYVVMPMRL Sbjct: 375 AYVVMPMRL 383 >6AP4-A nrPDB Length = 388 Score = 309 bits (792), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 174/383 (45%), Positives = 236/383 (61%), Gaps = 18/383 (4%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 M+ + +E LL L V G + R TL IL N+ +Q L++TG+DLE+E+VA AL Sbjct: 7 MRLKIAKESLLNVLSHVVGAVERRHTLNILSNVKIQTNAQALTITGSDLEVELVASTALS 66 Query: 61 QPH--EPGATTVPARKFFDICRGLPEGAEIAVQL-EGERMLVRSGRSRFSLSTLPAADFP 117 + E G TTVPARK +IC+ LP A I +Q+ E +R +++SG SRF L TLPA D+P Sbjct: 67 EGACLEAGETTVPARKLMEICKSLPTAALIDLQITEDQRCILKSGNSRFVLGTLPAEDYP 126 Query: 118 NLDDWQSE-VEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHR 176 L S+ + + Q +KRL E T F+MA QDVR+YL G L E + +LR V TDGHR Sbjct: 127 LLTTENSQGTQVQVTQRELKRLFEKTAFAMAVQDVRFYLTGTLLEIDENQLRAVTTDGHR 186 Query: 177 LAVCSMPIGQSLPSHSV--IVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHV------- 227 LA+C + + S S V IVPRK V EL R+L D L + IG + + Sbjct: 187 LALCEI-LASSTSSQLVQAIVPRKAVGELQRLLSIEDEQLTLLIGRELLNVTINTPSRDK 245 Query: 228 --GDFI--FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRL 283 GD FT+KL+DG+FPDYRRV+P+ DKH+ G D+ KQ+ R AILSNEK RGV L Sbjct: 246 EQGDITVRFTTKLIDGKFPDYRRVIPRGGDKHVLIGHDVFKQSLQRVAILSNEKLRGVFL 305 Query: 284 YVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDS 343 +++ L++ ANNPEQ+EA E L + Y A +E+ FN Y+LDVL L ++V M +T++ Sbjct: 306 NFNQDSLQLRANNPEQDEAIEDLAIQYQSAPLEMSFNAQYLLDVLGVLDGDDVNMSMTEA 365 Query: 344 VSSVQIEDAASQSAAYVVMPMRL 366 SV ++D A YVVMPMR+ Sbjct: 366 NQSVLVQDPAHPDQTYVVMPMRV 388 >5WCE-A nrPDB Length = 379 Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 141/373 (37%), Positives = 206/373 (55%), Gaps = 8/373 (2%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK T+ER LLK L V + R T+PIL N+LL LS + TDL+ME++ Sbjct: 8 MKLTIERAALLKALGHVQSVVERRNTIPILSNILLSAEGDRLSFSATDLDMEIIDE-GFA 66 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE--RMLVRSGRSRFSLSTLPAADFPN 118 Q PG T PA ++I R LP+GA++++ G+ R+++++GRSRF+L LPA DFP Sbjct: 67 QIDVPGQITAPAHTLYEIVRKLPDGADVSLSFSGDDPRLVIQAGRSRFNLPVLPAGDFPV 126 Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFET--EGEE--LRTVATDG 174 + + + RLI+ T+F+++ ++ RYYLNG+ T EG E LR VATDG Sbjct: 127 MSSDGLSSRIAVDTNELIRLIDKTRFAISTEETRYYLNGLYVHTVNEGGETKLRAVATDG 186 Query: 175 HRLAVCSMPIGQ-SLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233 HRLA+ MP + ++ VIVPRK + E R+++ + +Q+ +R G T Sbjct: 187 HRLALAEMPAPEGAVGIPGVIVPRKTIAEARRLMESAGETVDLQVSPQKVRFEFGAAALT 246 Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293 SK++DG FPDY RV+P++ K L DL +A R A +S EK R V+L V ++ +T Sbjct: 247 SKVIDGAFPDYMRVIPRDNAKILTLDNDLFAKAVDRVATISAEKSRSVKLAVEPGRITLT 306 Query: 294 ANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAA 353 N E +A E ++V Y G EIGFN Y+LDV + D S + D Sbjct: 307 VRNMEAGQAVEEVEVDYDGEPFEIGFNARYLLDVCGQIAGPQAEFRFADPASPTLVVDPV 366 Query: 354 SQSAAYVVMPMRL 366 YV+MP+R+ Sbjct: 367 DPGVKYVLMPLRV 379 >6DEG-A nrPDB Length = 381 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 144/376 (38%), Positives = 213/376 (56%), Gaps = 13/376 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 M+ TV+R K L +V + R T+PIL N+L+ +G++ L TDL++E V V Sbjct: 9 MRITVDRSQFFKSLGRVHRVVERRNTVPILSNVLIDAENGSVQLKATDLDLE-VTESFTV 67 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQL---EGERMLVRSGRSRFSLSTLPAADFP 117 + GA TVPA +DI R LP+G+EI + + + M + SG + F L LP DFP Sbjct: 68 NIEKAGAITVPAYLLYDIVRKLPDGSEIVLSVDENQASAMSIVSGCTHFQLQCLPKIDFP 127 Query: 118 NLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEE---LRTVATDG 174 Q F L + +K L++ TQF+++ ++ RYYLNG+ F ++ LR VATDG Sbjct: 128 ESLPGQFGCRFFLSASKLKHLLDCTQFAISTEETRYYLNGIYFHIVHDDVLKLRLVATDG 187 Query: 175 HRLAVCSM--PIG-QSLPSHSVIVPRKGVIELMRML-DGGDNPLRVQIGSNNIRAHVGDF 230 HRLA M P G +P VI+PRK V EL ++L + D + +++ IR +G Sbjct: 188 HRLAQVDMEAPSGVDGMPG--VIIPRKAVGELQKLLSEEIDGDVCIELSETKIRFSLGSV 245 Query: 231 IFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQL 290 +FTSKLVDG FPDY+RV+P D+ L A R + +SN++ R V+L + QL Sbjct: 246 VFTSKLVDGTFPDYQRVIPLGNDRKLIVNRQDFSSAVDRVSTISNDRGRAVKLTIEHGQL 305 Query: 291 KITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350 K+ NNP+ AE+ L TY+ +EIGFN Y+LD+ L + + ML+D+V+ I Sbjct: 306 KLVVNNPDSGSAEDQLAATYTSEPLEIGFNSRYLLDIAGQLSSDEMVFMLSDAVAPALIR 365 Query: 351 DAASQSAAYVVMPMRL 366 D + YV+MP+R+ Sbjct: 366 DNNNAEVLYVLMPVRV 381 >6MAN-A nrPDB Length = 387 Score = 187 bits (474), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 114/379 (30%), Positives = 194/379 (51%), Gaps = 14/379 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +K VE + L++ L S + R + L N+ L DG L L+ T++++ + ++ V Sbjct: 10 LKVIVETKTLVQALGFASSVVEKRNIISELANIKLLAKDGLLELSSTNMDLYLSQKIG-V 68 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 Q G TV + DI + LP+ L + + RF+L TLP FP +D Sbjct: 69 QVVSEGELTVSTKTLNDIVKKLPDSELTLTDLGTTGLEITGKNCRFNLFTLPVESFPVMD 128 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + E F + A ++IE+T+FS++ + RY LNG+ + E +TDGHRL+V Sbjct: 129 NINPEASFKISCAEFAKIIESTKFSVSLDETRYNLNGIYLHVKDSEFYAASTDGHRLSVS 188 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNP---LRVQIGSNNIRAHVG-DFIFTSKL 236 S+ + + + VI+P+K E+++++ N + + + SN I+ + I SKL Sbjct: 189 SVVLAEKIEDFGVILPQKSAEEILKIVKDSKNANADIEILLSSNKIKFICNENVIMLSKL 248 Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296 +DG FPDY +P+N L + R AI++ EKFR V+L +S L+I+A Sbjct: 249 IDGTFPDYSSFIPENSSSKLVINRKIFADTIERIAIITVEKFRAVKLSLSGEALEISAIG 308 Query: 297 PEQEEAEEILDVT--------YSG-AEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347 + A+E+++ + YSG ++IGFN Y+ DVL A+K + V + + + V Sbjct: 309 EARGNAKEVINSSKETENFYEYSGETNLDIGFNPQYLEDVLKAIKSDLVELYFSSVSAPV 368 Query: 348 QIEDAASQSAAYVVMPMRL 366 I+ S +VVMP+++ Sbjct: 369 LIKFPESPKDIFVVMPVKV 387 >6D46-A nrPDB Length = 389 Score = 184 bits (467), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 112/381 (29%), Positives = 201/381 (52%), Gaps = 16/381 (4%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +K VE + L++ L + R +P N+ L DG L L+ T++++ + ++A V Sbjct: 10 LKLIVETKTLVQSLGFARSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 Q G TV + DI R LP+ +L+ ++ ++ +F+L TLP + FP +D Sbjct: 69 QVLSEGEITVSTQTLSDIVRKLPDSELTLTELDIMKLEIKGQNCQFNLFTLPVSSFPAMD 128 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + EV F + A ++IE+T+FS++ + RY LNG+ + +E +TDGHRL++ Sbjct: 129 SIKPEVSFKISCADFAKIIESTKFSISLDETRYNLNGIYLHIKDKEFFAASTDGHRLSIS 188 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDN---PLRVQIGSNNIRAHVG-DFIFTSKL 236 + + + + + VI+P+K E+++++ N + + + SN I+ + I SKL Sbjct: 189 WITLEEKIKNFGVILPQKSAEEILKIVKDLKNIHEDIEILLSSNKIKFICNENTILLSKL 248 Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296 +DG FPDY +PK+ L + + R AI++ EKFR ++L +S L+I+A Sbjct: 249 IDGTFPDYSAFIPKSSISKLVINRKIFADSIERIAIITVEKFRAIKLSLSRKTLEISAVG 308 Query: 297 PEQEEAEEILDVT--------YSGAE-MEIGFNVSYVLDVLNALKCENVRMMLTDSVSS- 346 + A+EI+ + Y+ E + IGFN Y+ DVL A+K V + +D +S Sbjct: 309 EARGNAKEIITASQDKESFYEYNCDESLVIGFNPQYLEDVLKAVKSNLVELYFSDISASA 368 Query: 347 -VQIEDAASQSAAYVVMPMRL 366 V I+ + +V+MP+++ Sbjct: 369 PVLIKFPQNPKDIFVIMPVKV 389 >5W7Z-A nrPDB Length = 387 Score = 182 bits (462), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 109/379 (28%), Positives = 197/379 (51%), Gaps = 14/379 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +K VE + L++ L S + R +P N+ L DG L L+ T++++ + ++A V Sbjct: 10 LKLIVETKTLVQSLGFASSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 Q G TV + DI R LP+ L + ++ +F+L TLP + FP +D Sbjct: 69 QVVSEGECTVSTKTLNDIVRKLPDSELTLTDLGTTGLEIKGKNCKFNLFTLPVSSFPAMD 128 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 E F + ++IE+T+FS++ + RY LNG+ + +E + +TDGHRL++ Sbjct: 129 SINPEASFKISCTDFAKIIESTKFSISLDETRYNLNGVYLHIKDKEFCSASTDGHRLSIS 188 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDN---PLRVQIGSNNIRAHVGDFI-FTSKL 236 + + + + + VI+P+K E+++++ N + + + SN I+ + SKL Sbjct: 189 WVTLEKQIKNFGVILPQKSAEEILKIVKDPKNINEDIEILLSSNKIKFICNENTSMLSKL 248 Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296 +DG FPDY +P++ L + + R AI++ EKFR V+L +S L+I+A Sbjct: 249 IDGTFPDYSTFIPESSSSKLVINRKMFADSIERIAIITVEKFRAVKLSLSRETLEISAVG 308 Query: 297 PEQEEAEEILDVT--------YSGAE-MEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347 + A+E+++ + Y+ E + IGFN Y+ DVL A+K + V + +D + V Sbjct: 309 EARGNAKEVINSSQDKESFYEYNSDESLAIGFNPQYLEDVLKAVKSDVVELYFSDVSAPV 368 Query: 348 QIEDAASQSAAYVVMPMRL 366 I+ + +VVMP+++ Sbjct: 369 LIKFPENPKDIFVVMPVKV 387 >4TR6-A nrPDB Length = 380 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 100/379 (26%), Positives = 200/379 (52%), Gaps = 17/379 (4%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARV--- 57 MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + + Sbjct: 3 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 62 Query: 58 ----ALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112 +V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L Sbjct: 63 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 121 Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172 A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT Sbjct: 122 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 181 Query: 173 DGHRLAVCSMPIGQSLP---SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD 229 D HRLA+ + +P S++V++P K + EL ++LD + + I + + Sbjct: 182 DSHRLALRKAKL--DIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKN 239 Query: 230 FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE-- 287 +F S+L+DG +PD ++P++ + QA RA++L+ E V ++ Sbjct: 240 VLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPA 299 Query: 288 NQLKITANNPE-QEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSS 346 ++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++ Sbjct: 300 ESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRP 359 Query: 347 VQIEDAASQSAAYVVMPMR 365 I ++ +++P+R Sbjct: 360 FLIRTPNDETIVQLILPVR 378 >6E8D-A nrPDB Length = 512 Score = 158 bits (400), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 100/379 (26%), Positives = 200/379 (52%), Gaps = 17/379 (4%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARV--- 57 MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + + Sbjct: 39 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 98 Query: 58 ----ALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112 +V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L Sbjct: 99 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 157 Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172 A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT Sbjct: 158 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 217 Query: 173 DGHRLAVCSMPIGQSLP---SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD 229 D HRLA+ + +P S++V++P K + EL ++LD + + I + + Sbjct: 218 DSHRLALRKAKL--DIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKN 275 Query: 230 FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE-- 287 +F S+L+DG +PD ++P++ + QA RA++L+ E V ++ Sbjct: 276 VLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPA 335 Query: 288 NQLKITANNPE-QEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSS 346 ++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++ Sbjct: 336 ESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRP 395 Query: 347 VQIEDAASQSAAYVVMPMR 365 I ++ +++P+R Sbjct: 396 FLIRTPNDETIVQLILPVR 414 >1VPK-A nrPDB Length = 378 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 101/368 (27%), Positives = 178/368 (48%), Gaps = 5/368 (1%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK TV L + S L + PIL L +V DG + TDLE + A V Sbjct: 13 MKVTVTTLELKDKITIASKALAKKSVKPILAGFLFEVKDGNFYICATDLETGVKATVNAA 72 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIA-VQLEGERMLVRSGRSRFSLSTLPAADFPNL 119 + VP + + LP+ EI + LEG+ +++ SG + F ++T+PA +FP + Sbjct: 73 EISGEARFVVPGDVIQKMVKVLPD--EITELSLEGDALVISSGSTVFRITTMPADEFPEI 130 Query: 120 DDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAV 179 +S + F + + ++ ++E F+ A + LNG+ +E LR VA+DG RLA+ Sbjct: 131 TPAESGITFEVDTSLLEEMVEKVIFAAAKDEFMRNLNGVFWELHKNLLRLVASDGFRLAL 190 Query: 180 CSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNP-LRVQIGSNNIRAHVGDFIFTSKLVD 238 I + S ++ K + E+ +LD P + V+ + D ++VD Sbjct: 191 AEEQIENEEEA-SFLLSLKSMKEVQNVLDNTTEPTITVRYDGRRVSLSTNDVETVMRVVD 249 Query: 239 GRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPE 298 FPDY+RV+P+ + L+++ R +++++ V+ + EN +++ + +P+ Sbjct: 250 AEFPDYKRVIPETFKTKVVVSRKELRESLKRVMVIASKGSESVKFEIEENVMRLVSKSPD 309 Query: 299 QEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAA 358 E + ++V G ++ I FN ++ DVL ++ E + M DS S QI Sbjct: 310 YGEVVDEVEVQKEGEDLVIAFNPKFIEDVLKHIETEEIEMNFVDSTSPCQINPLDISGYL 369 Query: 359 YVVMPMRL 366 Y+VMP+RL Sbjct: 370 YIVMPIRL 377 >4TRT-A nrPDB Length = 368 Score = 137 bits (345), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 102/348 (29%), Positives = 175/348 (50%), Gaps = 12/348 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK V ++ L + L + + R + P+L L ++ ++G L+L+GT+LE+++ V Sbjct: 2 MKANVTKKTLNEGLGLLERVIPSRSSNPLLTALKVETSEGGLTLSGTNLEIDLSCFVP-A 60 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + +P VPA F I R L G + ++L G+ + VRSG S F L T +P L Sbjct: 61 EVQQPENFVVPAHLFAQIVRNLG-GELVELELSGQELSVRSGGSDFKLQTGDIEAYPPLS 119 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + ++ + +L + R + +++ +++ + G+ E GE R VA+DG+R+A+ Sbjct: 120 -FPAQADVSLDGGELSRAFSSVRYAASNEAFQAVFRGIKLEHHGESARVVASDGYRVAIR 178 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240 P S ++I+P + V EL+R+L G+ R G + KL+DG Sbjct: 179 DFP--ASGDGKNLIIPARSVDELIRVLKDGE--ARFTYGDGMLTVTTDRVKMNLKLLDGD 234 Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNPEQ 299 FPDY RV+PK+ + LK+A R A+L+++ V VSE L++ A + Sbjct: 235 FPDYERVIPKDIKLQVTLPATALKEAVNRVAVLADKNANNRVEFLVSEGTLRLAAEG-DY 293 Query: 300 EEAEEILDVTYSGAE--MEIGFNVSYVLDVLNALKCENVRMMLTDSVS 345 A++ L VT G E M + FN +VLD L + + ++ + S S Sbjct: 294 GRAQDTLSVTQGGTEQAMSLAFNARHVLDALGPIDGD-AELLFSGSTS 340 >3P16-A nrPDB Length = 408 Score = 132 bits (333), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 110/393 (27%), Positives = 178/393 (45%), Gaps = 32/393 (8%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 + F + RE + V+ L RP +P+L +LL +D L+++G D E+ A+V Sbjct: 19 LTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVG-A 77 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + PG+ V R DI R LP + V +EG R+ + G +RFSL T+P D+P L Sbjct: 78 EIVSPGSVLVSGRLLSDITRALPN-KPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLP 136 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 E LP I + D L G+ E GE + ATD RLAV Sbjct: 137 TLPEETGL-LPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVR 195 Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIF------ 232 + S P +V+VP K + E + GG + +R+ +G+ G Sbjct: 196 ELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSD-VRLSLGTGPGVGKDGLLGISGNGKR 254 Query: 233 -TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLK 291 T++L+D FP +R++LP L +A A++++ + VR+ ++ ++ Sbjct: 255 STTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQ-VRMEFADGSVR 313 Query: 292 ITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDS-----VSS 346 ++A + AEE L V Y+G + I FN +Y+ D L++L+ E V T + + Sbjct: 314 LSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRP 373 Query: 347 VQIED-------------AASQSAAYVVMPMRL 366 V +D A S Y++MP+RL Sbjct: 374 VSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRL 406 >5AH4-A nrPDB Length = 401 Score = 125 bits (313), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 113/393 (28%), Positives = 177/393 (45%), Gaps = 35/393 (8%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +KF V RE + V+ L RPT+P+L +LL D L+++G D E+ +V+ Sbjct: 15 LKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVS-A 73 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + G+ V R DI + LP + V +EG R+ + G +RFSL TL D+P L Sbjct: 74 EIASAGSVLVSGRLLSDITKALP-AKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALP 132 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 E + I + D L G+ E GE + ATD RLAV Sbjct: 133 ALPEETGV-IASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVR 191 Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVG-DFIF----- 232 + + +V+VP K + E + G N + + +GS A VG D + Sbjct: 192 ELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDG-NQVHLALGSG---ASVGKDGLLGIRSE 247 Query: 233 ----TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSEN 288 T++L+D FP +R++LP G L +A R A++++ + +R+ S++ Sbjct: 248 GKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQ-IRMEFSDD 306 Query: 289 QLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTD----SV 344 LK++A + AEE L V ++G + I FN +Y+ D L +L E V T +V Sbjct: 307 TLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAV 366 Query: 345 SSVQIED-----------AASQSAAYVVMPMRL 366 ED AA Y++MP+RL Sbjct: 367 LRPAGEDDGANGGSGPFPAAKTDYVYLLMPVRL 399 >6D47-A nrPDB Length = 410 Score = 124 bits (310), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 99/349 (28%), Positives = 162/349 (46%), Gaps = 12/349 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +KF + RE + V+ L RP +P+L +LL +D L+++G D E+ RV Sbjct: 21 LKFRLVRESFADAVSWVAKNLPTRPAVPVLSGVLLTGSDEGLTISGFDYEVSAEVRVP-A 79 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + PG V R DI R LP + ++G R+ + G +RFSL T+ D+P L Sbjct: 80 EIASPGTVLVSGRLLSDITRALPN-KPVDFYVDGNRVALTCGNARFSLPTMAVEDYPTLP 138 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + TLP I + D L G+ E GE++ ATD RLAV Sbjct: 139 TLPEDTG-TLPAELFSEAIGQVAIAAGRDDTLPMLTGIRVEISGEKVVLAATDRFRLAVR 197 Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRM-LDGGDNPLRVQ----IGSNNIRAHVGDFI-F 232 + P +V+VP K + E + DG + L + +G + + GD Sbjct: 198 ELTWNALSPDIEAAVLVPAKTLGEAAKANTDGSEVRLSLGAGMGVGKDGLLGISGDGKRS 257 Query: 233 TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKI 292 T++L+D FP +R++LP A L +A A++++ + VR+ ++ L++ Sbjct: 258 TTRLLDAEFPKFRQLLPAEHTAVASADVAELTEAIKLVALVADRGAQ-VRMEFADGMLRL 316 Query: 293 TANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLT 341 +A + AEE + V ++G + I FN +Y++D L +L E V T Sbjct: 317 SAGADDVGRAEEDIAVEFAGQPLTIAFNPTYLIDGLASLHSERVSFGFT 365 >2AVT-A nrPDB Length = 378 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 82/347 (23%), Positives = 170/347 (48%), Gaps = 9/347 (2%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 ++F++ R + L + + +PIL ++ ++V ++LTG++ ++ + + + Sbjct: 2 IQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVS 61 Query: 61 QPH------EPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAA 114 + PGA + A F +I LP+ + ++E ++++ SG+S +L Sbjct: 62 NENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVD 121 Query: 115 DFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGM-LFETEGEELRTVATD 173 +P L + +E L +K +I T F+ + Q+ R L G+ + + ++ + VATD Sbjct: 122 QYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATD 181 Query: 174 GHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233 HR++ + + + V++P K + E + + V + I F Sbjct: 182 SHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFY 241 Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKI 292 ++L++G +PD R+L + + L+ A RA ++SN G V+L +++N + Sbjct: 242 TRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISA 301 Query: 293 TANNPEQEEAEEILD-VTYSGAEMEIGFNVSYVLDVLNALKCENVRM 338 N+PE + E LD V+ SG+++ I FN +Y+++ L A+K E V++ Sbjct: 302 HVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKI 348 >2AWA-A nrPDB Length = 390 Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 79/353 (22%), Positives = 172/353 (48%), Gaps = 13/353 (3%) Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQP 62 F++ + L+ L + + +PIL + + V + ++L G++ ++ + ++ Q Sbjct: 16 FSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFIS--QK 73 Query: 63 HEP--------GATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAA 114 +E G+ + A F ++ LP+ ++E ++++ SG+S +L + Sbjct: 74 NEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSE 133 Query: 115 DFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFE-TEGEELRTVATD 173 +P + + + L +K++I T F+ + Q+ R L G+ F ++ +EL+TVATD Sbjct: 134 QYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATD 193 Query: 174 GHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233 HRL+ + + ++ V++P + + E + + + +N I + F Sbjct: 194 SHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFY 253 Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKI 292 ++L++G +PD R++P + + + L+Q+ RA +LS+ G V+L + + + Sbjct: 254 TRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSA 313 Query: 293 TANNPEQEEAEEILDV-TYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSV 344 ++PE + E +D +G ++ I FN +Y++D L AL E V + +V Sbjct: 314 HVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAV 366 >3T0P-A nrPDB Length = 371 Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 85/369 (23%), Positives = 172/369 (46%), Gaps = 7/369 (1%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK + +LLK + VS + R T+ IL +L+ + + L D+E+ + + Sbjct: 2 MKLICSKANLLKGVNIVSKAVPTRTTMAILECILIDASANEIKLMANDMELG-IETIIDG 60 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE-RMLVRSGRSRFSLSTLPAADFPNL 119 E G + A+ F +I R LP+ ++ ++ + + ++ +++F++ DF + Sbjct: 61 TIEERGIIALDAKIFSEIVRKLPDN-DVTIETDASFKTVISCEKAKFNIIGKSGDDFSYI 119 Query: 120 DDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAV 179 + L Q T+K +I T FS+A D + G LFE E +LR V+ DGHR+++ Sbjct: 120 PYVERNESIVLSQFTLKEVIRQTIFSIADNDNNKLMTGELFEIEENKLRVVSLDGHRISI 179 Query: 180 CSMPIGQSLPSHSVIVPRKGVIELMRMLDG-GDNPLRVQIGSNNIRAHVGDFIFTSKLVD 238 + + S V+VP K + E+ +++ G D + + I +N+I + S+L++ Sbjct: 180 RYIEMKNHYDSKKVVVPGKTLQEISKIIPGSADEDVVIYITNNHIVFEFENTTVVSRLIE 239 Query: 239 GRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNP 297 G + ++L + D + L RA +L E + + + +++ +++ N+ Sbjct: 240 GEYFKIDQMLSSDYDTKVRINKRELLDCIDRATLLVKEGDKKPIIMNITDGNMELRINSF 299 Query: 298 EQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSA 357 E+I M IGFN + +D L + E V + + + + I+D + Sbjct: 300 IGSMNEDIDIDKDGKDIM-IGFNPKFFIDALRVIDEEEVNLYMVNPKAPCFIKDDEGK-F 357 Query: 358 AYVVMPMRL 366 Y+++P+ Sbjct: 358 IYLILPVNF 366 >6DJ8-A nrPDB Length = 393 Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 76/385 (19%), Positives = 163/385 (42%), Gaps = 28/385 (7%) Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQP 62 F E ++ +++ G + R I LL++V L + TD + + +++V Sbjct: 15 FICETNQIMNEIEKAKGIILNRNMNDIWSALLIEVKKSNLIIKSTDRNIFFESTISIVSE 74 Query: 63 HEPGATTVPARKFFDICRGLPEGAEIAVQL---------------EGERMLVRSGRSRFS 107 + + A F+D + +I + E E FS Sbjct: 75 TD-FKVLINASNFYDAVKAFNFYKKIKIVFNENNSKLEIMGELNDEKEEYEDHLKEPTFS 133 Query: 108 LSTLPAADFPNLD-DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF-ETEGE 165 + ++ ++ D+ +E + Q + K++I FS + + LNG+ F + E Sbjct: 134 YEEIENYNYDMVNEDYTFGIE--IKQKSFKKVINRIAFSAHLDESKNVLNGVYFSKDEDS 191 Query: 166 ELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRA 225 +L V+T+GHR+++C + + IVP K + ++ L G+ ++++ Sbjct: 192 KLLLVSTNGHRMSICKTEVIVE-EDVNFIVPVK-IFNFLKHLMSGEGMVKIKFSDKKFYV 249 Query: 226 HVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYV 285 ++ L++G +PDY+ ++PK +LK AR + +K R + L Sbjct: 250 EFDNYKIACSLINGNYPDYKSIIPKEQKNKSLVSLGILKDRLARVNLYV-DKSRKLVLTF 308 Query: 286 SENQLKITANNPEQEEAEEIL----DVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLT 341 SE QLK+ + E + Y GA+ + N+SY ++ ++ + + + Sbjct: 309 SELQLKLLGEDLITGRKGEFFIKDPNYLYDGADEVMAINISYFVEAISVFETSKIEIQF- 367 Query: 342 DSVSSVQIEDAASQSAAYVVMPMRL 366 +S + +++ + + + +++MPM L Sbjct: 368 NSGNVLKLSEPENFNFTHLIMPMSL 392 >4S3I-A nrPDB Length = 384 Score = 81.3 bits (199), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 79/349 (22%), Positives = 156/349 (44%), Gaps = 35/349 (10%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK +V + L L+ + L + I ++ L+V L L +D ++ + + + Sbjct: 3 MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSDIGLKSYIFTQ 62 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + G T+ +KF DI L + + I ++ + + + ++ +S F L A +FP Sbjct: 63 SSDKEGVGTINGKKFLDIISCLKD-SNIILETKDDSLAIKQNKSSFKLPMFDADEFPEFP 121 Query: 121 --DWQSEVEFTLP--QATMKRL---IEATQFSMAHQDVRYYLNGML--FETEGEELRTVA 171 D + +E P K++ IE T +H + L G+L F+ + + L V Sbjct: 122 VIDPKVSIEVNAPFLVDAFKKIAPVIEQT----SH---KRELAGILMQFDQKHQTLSVVG 174 Query: 172 TDGHRLAVCSM---PIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVG 228 TD RL+ + I + S I+P++ ++E++++ S+ + A + Sbjct: 175 TDTKRLSYTQLEKISIHSTEEDISCILPKRALLEILKLFYEN-----FSFKSDGMLAVIE 229 Query: 229 D--FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVS 286 + F +KL+DG +PDY+++LPK G + K++ + LS+ ++L + Sbjct: 230 NEMHTFFTKLIDGNYPDYQKILPKEYISSFTLGKEEFKESIKLCSSLSS----TIKLTLE 285 Query: 287 ENQLKITANNPEQEEAEEILDVTYSGAEME----IGFNVSYVLDVLNAL 331 +N + + E E + G ++E +G N + L+ LNAL Sbjct: 286 KNNALFESLDSEHSETAKTSVEIEKGLDIEKAFHLGVNAKFFLEALNAL 334 >5Y86-A nrPDB Length = 588 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 29/112 (25%), Positives = 46/112 (41%), Gaps = 10/112 (8%) Query: 21 LGGRPTLPI----LGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPAR-KF 75 LG R + PI G +L ++ G G D ++ + L+ P R K+ Sbjct: 382 LGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMMELLGMPPPKLLEQSKRAKY 441 Query: 76 FDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVE 127 F +G+P + Q +G +LV GRSR P P DW + ++ Sbjct: 442 FINSKGIPRYCSVTTQADGRVVLV-GGRSRRGKKRGP----PGSKDWGTALK 488 >3HPX-A nrPDB Length = 425 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 40/144 (27%), Positives = 58/144 (40%), Gaps = 23/144 (15%) Query: 25 PTLPILGNLLLQVADGTLSLTGTDLEM---EMVARVALV---QPHEPGATTVPARKFFDI 78 P PI+ NL V T ++ +E + R +++ PH T V A + Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAEL--- 299 Query: 79 CRGLPEGA---EIAVQLEGER----MLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLP 131 G GA E + GER LV G + FS P DF N+D+ + VE+ Sbjct: 300 --GFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQ 357 Query: 132 QATMKRL-----IEATQFSMAHQD 150 +R + T FS +HQD Sbjct: 358 LPVHERHPYGGDLVYTAFSGSHQD 381 >3MWB-A nrPDB Length = 313 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 25/156 (16%) Query: 163 EGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI---- 218 E +++ ++T GH A C + + + LP+ + M +L+ D P I Sbjct: 101 ELSDIKRISTHGHAWAQCRLWVDEHLPNADYVPGSSTAASAMGLLE-DDAPYEAAICAPL 159 Query: 219 ------GSNNIRAHVGD-------FIFTSKLVDGRFP-----DYRRVLPKNPDKHLEAGC 260 G N + +GD FI S+ G P D V+ P+ H A Sbjct: 160 IAAEQPGLNVLAEDIGDNPDAVTRFILVSR--PGALPERTGADKTTVVVPLPEDHPGALM 217 Query: 261 DLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296 ++L Q +R LS + R Y+ I A+ Sbjct: 218 EILDQFASRGVNLSRIESRPTGQYLGHYFFSIDADG 253 >3HQ1-A nrPDB Length = 644 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 40/144 (27%), Positives = 58/144 (40%), Gaps = 23/144 (15%) Query: 25 PTLPILGNLLLQVADGTLSLTGTDLEM---EMVARVALV---QPHEPGATTVPARKFFDI 78 P PI+ NL V T ++ +E + R +++ PH T V A + Sbjct: 243 PERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAEL--- 299 Query: 79 CRGLPEGA---EIAVQLEGERM----LVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLP 131 G GA E + GER LV G + FS P DF N+D+ + VE+ Sbjct: 300 --GFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQ 357 Query: 132 QATMKRL-----IEATQFSMAHQD 150 +R + T FS +HQD Sbjct: 358 LPVHERHPYGGDLVYTAFSGSHQD 381 >4EWP-A nrPDB Length = 350 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 15/92 (16%) Query: 26 TLPILGNLLLQVADGTLSLTGTDLEMEMVARV---------ALVQPHEPGATTVPARKFF 76 T+P++ + A L G+DL+ +V+ V A + HE GAT PA Sbjct: 61 TVPVMAVGAAREALERAGLQGSDLDAVIVSTVTFPHATPSAAALVAHEIGATPAPAYDVS 120 Query: 77 DICRGLPEGAEIAVQLEGERMLVRSGRSRFSL 108 C G G A LVRSG +R L Sbjct: 121 AACAGYCYGVAQA------DALVRSGTARHVL 146 >3BH7-B nrPDB Length = 352 Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 23/128 (17%) Query: 191 HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPK 250 +++ RK + E++ G VQ +++A +F K PD+ +L K Sbjct: 247 YTIANARKLIDEMV-----GKGFFLVQTKEVSMKAEDAQRVFREKA-----PDFLPLLNK 296 Query: 251 NPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTY 310 P LE D A ++ NE F G +++VSE+ +E A +D Y Sbjct: 297 GPVIALEFNGD---GAVEVCQLIVNEIFNGTKMFVSES----------KETASGDVDSFY 343 Query: 311 SGAEMEIG 318 + A++++G Sbjct: 344 NFADIQMG 351 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6E8E-B nrPDB 465 e-131 5X06-A nrPDB 458 e-129 4TR8-A nrPDB 408 e-114 6DEG-A nrPDB 396 e-111 5WCE-A nrPDB 393 e-110 5W7Z-A nrPDB 381 e-106 6AP4-A nrPDB 377 e-105 6D46-A nrPDB 374 e-104 6MAN-A nrPDB 370 e-103 3P16-A nrPDB 367 e-102 5AH4-A nrPDB 365 e-101 6D47-A nrPDB 364 e-101 6E8D-A nrPDB 362 e-100 4TR6-A nrPDB 356 1e-98 1VPK-A nrPDB 344 3e-95 2AVT-A nrPDB 341 3e-94 2AWA-A nrPDB 341 3e-94 3T0P-A nrPDB 325 2e-89 4TRT-A nrPDB 315 2e-86 6DJ8-A nrPDB 292 2e-79 4S3I-A nrPDB 259 1e-69 Sequences not found previously or not previously below threshold: 3K4X-A nrPDB 52 5e-07 1AZW-A nrPDB 42 6e-04 5ZUT-A nrPDB 40 0.002 4L60-A nrPDB 38 0.006 1RXZ-A nrPDB 36 0.033 1V6S-A nrPDB 33 0.18 5XNX-A nrPDB 33 0.19 6G1M-A nrPDB 32 0.35 4NV8-A nrPDB 30 2.0 2BSZ-A nrPDB 30 2.0 2R5V-A nrPDB 30 2.4 3IBD-A nrPDB 29 2.9 5E58-A nrPDB 29 2.9 5E0E-A nrPDB 29 3.1 5A6D-A nrPDB 28 5.7 2IX2-C nrPDB 28 5.7 >6E8E-B nrPDB Length = 517 Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats. Identities = 366/366 (100%), Positives = 366/366 (100%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV Sbjct: 39 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 98 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD Sbjct: 99 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 158 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC Sbjct: 159 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 218 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR Sbjct: 219 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 278 Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE Sbjct: 279 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 338 Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV Sbjct: 339 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 398 Query: 361 VMPMRL 366 VMPMRL Sbjct: 399 VMPMRL 404 >5X06-A nrPDB Length = 386 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 366/366 (100%), Positives = 366/366 (100%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV Sbjct: 21 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 80 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD Sbjct: 81 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 140 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC Sbjct: 141 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 200 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR Sbjct: 201 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 260 Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE Sbjct: 261 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 320 Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 360 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV Sbjct: 321 EAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYV 380 Query: 361 VMPMRL 366 VMPMRL Sbjct: 381 VMPMRL 386 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 46/128 (35%), Gaps = 2/128 (1%) Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLA 178 L S ++FT+ + + + ++ + + L +L + L TD Sbjct: 14 LVPRGSHMKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEM 73 Query: 179 VCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIF-TSKLV 237 V + + Q + VP + ++ R L G + VQ+ + G F S L Sbjct: 74 VARVALVQPHEPGATTVPARKFFDICRGLPEGAE-IAVQLEGERMLVRSGRSRFSLSTLP 132 Query: 238 DGRFPDYR 245 FP+ Sbjct: 133 AADFPNLD 140 >4TR8-A nrPDB Length = 383 Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats. Identities = 203/367 (55%), Positives = 264/367 (71%), Gaps = 1/367 (0%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 M FT++RE LLKPLQ V+G + R TLP+L N+LL V LSLTGTDLE+E+V RV L Sbjct: 17 MHFTIQREALLKPLQLVAGVVERRQTLPVLSNVLLVVEGQQLSLTGTDLEVELVGRVVLE 76 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 EPG TVPARK DIC+ LP I +++E +++LV++GRSRF+LSTLPA DFP ++ Sbjct: 77 DAAEPGEITVPARKLMDICKSLPNDVLIDIRVEEQKLLVKAGRSRFTLSTLPANDFPTVE 136 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + + F++ Q+ ++RLI+ T F+MA QDVRYYLNGML E G LR+VATDGHRLA+C Sbjct: 137 EGPGSLNFSIAQSKLRRLIDRTSFAMAQQDVRYYLNGMLLEVNGGTLRSVATDGHRLAMC 196 Query: 181 SMPIGQSLPS-HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDG 239 S+ H VIVPRKG++EL R+L D + + +G ++IRA G+F FTSKLVDG Sbjct: 197 SLDAQIPSQDRHQVIVPRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDG 256 Query: 240 RFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ 299 +FPDY RVLP+ DK + L++AF+R AILSNEK+RG+RL +S LKI ANNPEQ Sbjct: 257 KFPDYERVLPRGGDKLVVGDRQQLREAFSRTAILSNEKYRGIRLQLSNGLLKIQANNPEQ 316 Query: 300 EEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAY 359 EEAEE + V Y+G +EIGFNVSY+LDVL + E VR +L+DS SS + +A + +AY Sbjct: 317 EEAEEEVQVEYNGGNLEIGFNVSYLLDVLGVIGTEQVRFILSDSNSSALVHEADNDDSAY 376 Query: 360 VVMPMRL 366 VVMPMRL Sbjct: 377 VVMPMRL 383 >6DEG-A nrPDB Length = 381 Score = 396 bits (1017), Expect = e-111, Method: Composition-based stats. Identities = 141/374 (37%), Positives = 210/374 (56%), Gaps = 9/374 (2%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 M+ TV+R K L +V + R T+PIL N+L+ +G++ L TDL++E V V Sbjct: 9 MRITVDRSQFFKSLGRVHRVVERRNTVPILSNVLIDAENGSVQLKATDLDLE-VTESFTV 67 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGER---MLVRSGRSRFSLSTLPAADFP 117 + GA TVPA +DI R LP+G+EI + ++ + M + SG + F L LP DFP Sbjct: 68 NIEKAGAITVPAYLLYDIVRKLPDGSEIVLSVDENQASAMSIVSGCTHFQLQCLPKIDFP 127 Query: 118 NLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGE---ELRTVATDG 174 Q F L + +K L++ TQF+++ ++ RYYLNG+ F + +LR VATDG Sbjct: 128 ESLPGQFGCRFFLSASKLKHLLDCTQFAISTEETRYYLNGIYFHIVHDDVLKLRLVATDG 187 Query: 175 HRLAVCSMPIGQSLPS-HSVIVPRKGVIELMRMLDGG-DNPLRVQIGSNNIRAHVGDFIF 232 HRLA M + VI+PRK V EL ++L D + +++ IR +G +F Sbjct: 188 HRLAQVDMEAPSGVDGMPGVIIPRKAVGELQKLLSEEIDGDVCIELSETKIRFSLGSVVF 247 Query: 233 TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKI 292 TSKLVDG FPDY+RV+P D+ L A R + +SN++ R V+L + QLK+ Sbjct: 248 TSKLVDGTFPDYQRVIPLGNDRKLIVNRQDFSSAVDRVSTISNDRGRAVKLTIEHGQLKL 307 Query: 293 TANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDA 352 NNP+ AE+ L TY+ +EIGFN Y+LD+ L + + ML+D+V+ I D Sbjct: 308 VVNNPDSGSAEDQLAATYTSEPLEIGFNSRYLLDIAGQLSSDEMVFMLSDAVAPALIRDN 367 Query: 353 ASQSAAYVVMPMRL 366 + YV+MP+R+ Sbjct: 368 NNAEVLYVLMPVRV 381 >5WCE-A nrPDB Length = 379 Score = 393 bits (1010), Expect = e-110, Method: Composition-based stats. Identities = 139/373 (37%), Positives = 205/373 (54%), Gaps = 8/373 (2%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK T+ER LLK L V + R T+PIL N+LL LS + TDL+ME++ Sbjct: 8 MKLTIERAALLKALGHVQSVVERRNTIPILSNILLSAEGDRLSFSATDLDMEIIDE-GFA 66 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE--RMLVRSGRSRFSLSTLPAADFPN 118 Q PG T PA ++I R LP+GA++++ G+ R+++++GRSRF+L LPA DFP Sbjct: 67 QIDVPGQITAPAHTLYEIVRKLPDGADVSLSFSGDDPRLVIQAGRSRFNLPVLPAGDFPV 126 Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGE----ELRTVATDG 174 + + + RLI+ T+F+++ ++ RYYLNG+ T E +LR VATDG Sbjct: 127 MSSDGLSSRIAVDTNELIRLIDKTRFAISTEETRYYLNGLYVHTVNEGGETKLRAVATDG 186 Query: 175 HRLAVCSMPIGQ-SLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233 HRLA+ MP + ++ VIVPRK + E R+++ + +Q+ +R G T Sbjct: 187 HRLALAEMPAPEGAVGIPGVIVPRKTIAEARRLMESAGETVDLQVSPQKVRFEFGAAALT 246 Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293 SK++DG FPDY RV+P++ K L DL +A R A +S EK R V+L V ++ +T Sbjct: 247 SKVIDGAFPDYMRVIPRDNAKILTLDNDLFAKAVDRVATISAEKSRSVKLAVEPGRITLT 306 Query: 294 ANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAA 353 N E +A E ++V Y G EIGFN Y+LDV + D S + D Sbjct: 307 VRNMEAGQAVEEVEVDYDGEPFEIGFNARYLLDVCGQIAGPQAEFRFADPASPTLVVDPV 366 Query: 354 SQSAAYVVMPMRL 366 YV+MP+R+ Sbjct: 367 DPGVKYVLMPLRV 379 Score = 35.0 bits (79), Expect = 0.057, Method: Composition-based stats. Identities = 35/266 (13%), Positives = 81/266 (30%), Gaps = 28/266 (10%) Query: 119 LDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLA 178 + ++ T+ +A + + + Q + ++ L+ +L EG+ L ATD Sbjct: 1 MHHHHHHMKLTIERAALLKALGHVQSVVERRNTIPILSNILLSAEGDRLSFSATDLDMEI 60 Query: 179 VCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSN--NIRAHVGDFIFTSKL 236 + +P + P + E++R L G + + + + G F + Sbjct: 61 IDEGFAQIDVPG-QITAPAHTLYEIVRKLPDGA-DVSLSFSGDDPRLVIQAGRSRFNLPV 118 Query: 237 VD-GRFP-------------DYRRVLPKNPDKHLEAGCDLLKQAFA--RAAILSNEKFRG 280 + G FP D ++ + + ++ Sbjct: 119 LPAGDFPVMSSDGLSSRIAVDTNELIRLIDKTRFAISTEETRYYLNGLYVHTVNEGGETK 178 Query: 281 VRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLN-----ALKCEN 335 +R ++ A P E A I V + +++ + + Sbjct: 179 LRAVATDGHRLALAEMPAPEGAVGIPGVIVPRKTIA---EARRLMESAGETVDLQVSPQK 235 Query: 336 VRMMLTDSVSSVQIEDAASQSAAYVV 361 VR + + ++ D A V+ Sbjct: 236 VRFEFGAAALTSKVIDGAFPDYMRVI 261 >5W7Z-A nrPDB Length = 387 Score = 381 bits (979), Expect = e-106, Method: Composition-based stats. Identities = 106/379 (27%), Positives = 193/379 (50%), Gaps = 14/379 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +K VE + L++ L S + R +P N+ L DG L L+ T++++ + ++A V Sbjct: 10 LKLIVETKTLVQSLGFASSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 Q G TV + DI R LP+ L + ++ +F+L TLP + FP +D Sbjct: 69 QVVSEGECTVSTKTLNDIVRKLPDSELTLTDLGTTGLEIKGKNCKFNLFTLPVSSFPAMD 128 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 E F + ++IE+T+FS++ + RY LNG+ + +E + +TDGHRL++ Sbjct: 129 SINPEASFKISCTDFAKIIESTKFSISLDETRYNLNGVYLHIKDKEFCSASTDGHRLSIS 188 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGD---NPLRVQIGSNNIRAHVG-DFIFTSKL 236 + + + + + VI+P+K E+++++ + + + SN I+ + SKL Sbjct: 189 WVTLEKQIKNFGVILPQKSAEEILKIVKDPKNINEDIEILLSSNKIKFICNENTSMLSKL 248 Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296 +DG FPDY +P++ L + + R AI++ EKFR V+L +S L+I+A Sbjct: 249 IDGTFPDYSTFIPESSSSKLVINRKMFADSIERIAIITVEKFRAVKLSLSRETLEISAVG 308 Query: 297 PEQEEAEEILDVTYSG---------AEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347 + A+E+++ + + IGFN Y+ DVL A+K + V + +D + V Sbjct: 309 EARGNAKEVINSSQDKESFYEYNSDESLAIGFNPQYLEDVLKAVKSDVVELYFSDVSAPV 368 Query: 348 QIEDAASQSAAYVVMPMRL 366 I+ + +VVMP+++ Sbjct: 369 LIKFPENPKDIFVVMPVKV 387 >6AP4-A nrPDB Length = 388 Score = 377 bits (968), Expect = e-105, Method: Composition-based stats. Identities = 169/382 (44%), Positives = 230/382 (60%), Gaps = 16/382 (4%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 M+ + +E LL L V G + R TL IL N+ +Q L++TG+DLE+E+VA AL Sbjct: 7 MRLKIAKESLLNVLSHVVGAVERRHTLNILSNVKIQTNAQALTITGSDLEVELVASTALS 66 Query: 61 QPH--EPGATTVPARKFFDICRGLPEGAEIAVQL-EGERMLVRSGRSRFSLSTLPAADFP 117 + E G TTVPARK +IC+ LP A I +Q+ E +R +++SG SRF L TLPA D+P Sbjct: 67 EGACLEAGETTVPARKLMEICKSLPTAALIDLQITEDQRCILKSGNSRFVLGTLPAEDYP 126 Query: 118 NLDDWQS-EVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHR 176 L S + + Q +KRL E T F+MA QDVR+YL G L E + +LR V TDGHR Sbjct: 127 LLTTENSQGTQVQVTQRELKRLFEKTAFAMAVQDVRFYLTGTLLEIDENQLRAVTTDGHR 186 Query: 177 LAVCSMPIGQSLPS-HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD------ 229 LA+C + + IVPRK V EL R+L D L + IG + + Sbjct: 187 LALCEILASSTSSQLVQAIVPRKAVGELQRLLSIEDEQLTLLIGRELLNVTINTPSRDKE 246 Query: 230 -----FIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLY 284 FT+KL+DG+FPDYRRV+P+ DKH+ G D+ KQ+ R AILSNEK RGV L Sbjct: 247 QGDITVRFTTKLIDGKFPDYRRVIPRGGDKHVLIGHDVFKQSLQRVAILSNEKLRGVFLN 306 Query: 285 VSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSV 344 +++ L++ ANNPEQ+EA E L + Y A +E+ FN Y+LDVL L ++V M +T++ Sbjct: 307 FNQDSLQLRANNPEQDEAIEDLAIQYQSAPLEMSFNAQYLLDVLGVLDGDDVNMSMTEAN 366 Query: 345 SSVQIEDAASQSAAYVVMPMRL 366 SV ++D A YVVMPMR+ Sbjct: 367 QSVLVQDPAHPDQTYVVMPMRV 388 >6D46-A nrPDB Length = 389 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 108/381 (28%), Positives = 197/381 (51%), Gaps = 16/381 (4%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +K VE + L++ L + R +P N+ L DG L L+ T++++ + ++A V Sbjct: 10 LKLIVETKTLVQSLGFARSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIA-V 68 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 Q G TV + DI R LP+ +L+ ++ ++ +F+L TLP + FP +D Sbjct: 69 QVLSEGEITVSTQTLSDIVRKLPDSELTLTELDIMKLEIKGQNCQFNLFTLPVSSFPAMD 128 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + EV F + A ++IE+T+FS++ + RY LNG+ + +E +TDGHRL++ Sbjct: 129 SIKPEVSFKISCADFAKIIESTKFSISLDETRYNLNGIYLHIKDKEFFAASTDGHRLSIS 188 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGD---NPLRVQIGSNNIRAHVG-DFIFTSKL 236 + + + + + VI+P+K E+++++ + + + SN I+ + I SKL Sbjct: 189 WITLEEKIKNFGVILPQKSAEEILKIVKDLKNIHEDIEILLSSNKIKFICNENTILLSKL 248 Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296 +DG FPDY +PK+ L + + R AI++ EKFR ++L +S L+I+A Sbjct: 249 IDGTFPDYSAFIPKSSISKLVINRKIFADSIERIAIITVEKFRAIKLSLSRKTLEISAVG 308 Query: 297 PEQEEAEEILDVTYSG---------AEMEIGFNVSYVLDVLNALKCENVRMMLTD--SVS 345 + A+EI+ + + IGFN Y+ DVL A+K V + +D + + Sbjct: 309 EARGNAKEIITASQDKESFYEYNCDESLVIGFNPQYLEDVLKAVKSNLVELYFSDISASA 368 Query: 346 SVQIEDAASQSAAYVVMPMRL 366 V I+ + +V+MP+++ Sbjct: 369 PVLIKFPQNPKDIFVIMPVKV 389 >6MAN-A nrPDB Length = 387 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 114/379 (30%), Positives = 193/379 (50%), Gaps = 14/379 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +K VE + L++ L S + R + L N+ L DG L L+ T++++ + ++ V Sbjct: 10 LKVIVETKTLVQALGFASSVVEKRNIISELANIKLLAKDGLLELSSTNMDLYLSQKIG-V 68 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 Q G TV + DI + LP+ L + + RF+L TLP FP +D Sbjct: 69 QVVSEGELTVSTKTLNDIVKKLPDSELTLTDLGTTGLEITGKNCRFNLFTLPVESFPVMD 128 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + E F + A ++IE+T+FS++ + RY LNG+ + E +TDGHRL+V Sbjct: 129 NINPEASFKISCAEFAKIIESTKFSVSLDETRYNLNGIYLHVKDSEFYAASTDGHRLSVS 188 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDN---PLRVQIGSNNIRAHVG-DFIFTSKL 236 S+ + + + VI+P+K E+++++ N + + + SN I+ + I SKL Sbjct: 189 SVVLAEKIEDFGVILPQKSAEEILKIVKDSKNANADIEILLSSNKIKFICNENVIMLSKL 248 Query: 237 VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANN 296 +DG FPDY +P+N L + R AI++ EKFR V+L +S L+I+A Sbjct: 249 IDGTFPDYSSFIPENSSSKLVINRKIFADTIERIAIITVEKFRAVKLSLSGEALEISAIG 308 Query: 297 PEQEEAEEILD--------VTYSGA-EMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSV 347 + A+E+++ YSG ++IGFN Y+ DVL A+K + V + + + V Sbjct: 309 EARGNAKEVINSSKETENFYEYSGETNLDIGFNPQYLEDVLKAIKSDLVELYFSSVSAPV 368 Query: 348 QIEDAASQSAAYVVMPMRL 366 I+ S +VVMP+++ Sbjct: 369 LIKFPESPKDIFVVMPVKV 387 >3P16-A nrPDB Length = 408 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 108/393 (27%), Positives = 177/393 (45%), Gaps = 32/393 (8%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 + F + RE + V+ L RP +P+L +LL +D L+++G D E+ A+V Sbjct: 19 LTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVG-A 77 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + PG+ V R DI R LP + V +EG R+ + G +RFSL T+P D+P L Sbjct: 78 EIVSPGSVLVSGRLLSDITRALPN-KPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLP 136 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 E LP I + D L G+ E GE + ATD RLAV Sbjct: 137 TLPEETGL-LPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVR 195 Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGS------NNIRAHVGDFI- 231 + S P +V+VP K + E + GG +R+ +G+ + + G+ Sbjct: 196 ELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGS-DVRLSLGTGPGVGKDGLLGISGNGKR 254 Query: 232 FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLK 291 T++L+D FP +R++LP L +A A++++ + VR+ ++ ++ Sbjct: 255 STTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQ-VRMEFADGSVR 313 Query: 292 ITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE- 350 ++A + AEE L V Y+G + I FN +Y+ D L++L+ E V T + + Sbjct: 314 LSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRP 373 Query: 351 -----------------DAASQSAAYVVMPMRL 366 A S Y++MP+RL Sbjct: 374 VSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRL 406 >5AH4-A nrPDB Length = 401 Score = 365 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 107/390 (27%), Positives = 170/390 (43%), Gaps = 29/390 (7%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +KF V RE + V+ L RPT+P+L +LL D L+++G D E+ +V+ Sbjct: 15 LKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVS-A 73 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + G+ V R DI + LP + V +EG R+ + G +RFSL TL D+P L Sbjct: 74 EIASAGSVLVSGRLLSDITKALP-AKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALP 132 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 E + I + D L G+ E GE + ATD RLAV Sbjct: 133 ALPEETGV-IASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVR 191 Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIF------ 232 + + +V+VP K + E + G N + + +GS G Sbjct: 192 ELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDG-NQVHLALGSGASVGKDGLLGIRSEGKR 250 Query: 233 -TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLK 291 T++L+D FP +R++LP G L +A R A++++ + +R+ S++ LK Sbjct: 251 STTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQ-IRMEFSDDTLK 309 Query: 292 ITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE- 350 ++A + AEE L V ++G + I FN +Y+ D L +L E V T + Sbjct: 310 LSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRP 369 Query: 351 --------------DAASQSAAYVVMPMRL 366 AA Y++MP+RL Sbjct: 370 AGEDDGANGGSGPFPAAKTDYVYLLMPVRL 399 >6D47-A nrPDB Length = 410 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 103/392 (26%), Positives = 171/392 (43%), Gaps = 30/392 (7%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 +KF + RE + V+ L RP +P+L +LL +D L+++G D E+ RV Sbjct: 21 LKFRLVRESFADAVSWVAKNLPTRPAVPVLSGVLLTGSDEGLTISGFDYEVSAEVRVP-A 79 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + PG V R DI R LP + ++G R+ + G +RFSL T+ D+P L Sbjct: 80 EIASPGTVLVSGRLLSDITRALPN-KPVDFYVDGNRVALTCGNARFSLPTMAVEDYPTLP 138 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + TLP I + D L G+ E GE++ ATD RLAV Sbjct: 139 TLPEDTG-TLPAELFSEAIGQVAIAAGRDDTLPMLTGIRVEISGEKVVLAATDRFRLAVR 197 Query: 181 SMPIGQSLPS--HSVIVPRKGVIELMRMLDGGDNP-----LRVQIGSNNIRAHVGDFI-F 232 + P +V+VP K + E + G + +G + + GD Sbjct: 198 ELTWNALSPDIEAAVLVPAKTLGEAAKANTDGSEVRLSLGAGMGVGKDGLLGISGDGKRS 257 Query: 233 TSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKI 292 T++L+D FP +R++LP A L +A A++++ + VR+ ++ L++ Sbjct: 258 TTRLLDAEFPKFRQLLPAEHTAVASADVAELTEAIKLVALVADRGAQ-VRMEFADGMLRL 316 Query: 293 TANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDA 352 +A + AEE + V ++G + I FN +Y++D L +L E V T + A Sbjct: 317 SAGADDVGRAEEDIAVEFAGQPLTIAFNPTYLIDGLASLHSERVSFGFTTPGKPALLRPA 376 Query: 353 AS------------------QSAAYVVMPMRL 366 ++ Y++MP+RL Sbjct: 377 SAEDRIVSGPGDQGPFAAVPTDYVYLLMPVRL 408 >6E8D-A nrPDB Length = 512 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 99/377 (26%), Positives = 198/377 (52%), Gaps = 13/377 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVA-- 58 MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + + Sbjct: 39 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 98 Query: 59 -----LVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112 +V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L Sbjct: 99 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 157 Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172 A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT Sbjct: 158 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 217 Query: 173 DGHRLAVCSMPIGQSLP-SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFI 231 D HRLA+ + S++V++P K + EL ++LD + + I + + + Sbjct: 218 DSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKNVL 277 Query: 232 FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE--NQ 289 F S+L+DG +PD ++P++ + QA RA++L+ E V ++ Sbjct: 278 FFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPAES 337 Query: 290 LKITANNPEQEEAEE-ILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQ 348 ++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++ Sbjct: 338 IEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRPFL 397 Query: 349 IEDAASQSAAYVVMPMR 365 I ++ +++P+R Sbjct: 398 IRTPNDETIVQLILPVR 414 >4TR6-A nrPDB Length = 380 Score = 356 bits (913), Expect = 1e-98, Method: Composition-based stats. Identities = 99/377 (26%), Positives = 198/377 (52%), Gaps = 13/377 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVA-- 58 MKFT++++ L++ +Q V + R T+PIL + + +D +S TG+D ++ + + + Sbjct: 3 MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKE 62 Query: 59 -----LVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERM-LVRSGRSRFSLSTLP 112 +V +PG+ + AR F +I + LP A + ++++ + + ++RSG++ F+L+ L Sbjct: 63 EGDKEIVTIEQPGSIVLQARFFSEIVKKLP-MATVEIEVQNQYLTIIRSGKAEFNLNGLD 121 Query: 113 AADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172 A ++P+L + +P +K LI T F+++ + R L G+ ++ E EL AT Sbjct: 122 ADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTAT 181 Query: 173 DGHRLAVCSMPIGQSLP-SHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFI 231 D HRLA+ + S++V++P K + EL ++LD + + I + + + Sbjct: 182 DSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKNVL 241 Query: 232 FTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSE--NQ 289 F S+L+DG +PD ++P++ + QA RA++L+ E V ++ Sbjct: 242 FFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPAES 301 Query: 290 LKITANNPEQEEAEE-ILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQ 348 ++I++N+PE + E I+ G E+ I F+ Y+LD L L+ +R+ T ++ Sbjct: 302 IEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRPFL 361 Query: 349 IEDAASQSAAYVVMPMR 365 I ++ +++P+R Sbjct: 362 IRTPNDETIVQLILPVR 378 >1VPK-A nrPDB Length = 378 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 99/367 (26%), Positives = 175/367 (47%), Gaps = 3/367 (0%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK TV L + S L + PIL L +V DG + TDLE + A V Sbjct: 13 MKVTVTTLELKDKITIASKALAKKSVKPILAGFLFEVKDGNFYICATDLETGVKATVNAA 72 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + VP + + LP+ + LEG+ +++ SG + F ++T+PA +FP + Sbjct: 73 EISGEARFVVPGDVIQKMVKVLPD-EITELSLEGDALVISSGSTVFRITTMPADEFPEIT 131 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 +S + F + + ++ ++E F+ A + LNG+ +E LR VA+DG RLA+ Sbjct: 132 PAESGITFEVDTSLLEEMVEKVIFAAAKDEFMRNLNGVFWELHKNLLRLVASDGFRLALA 191 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNP-LRVQIGSNNIRAHVGDFIFTSKLVDG 239 I S ++ K + E+ +LD P + V+ + D ++VD Sbjct: 192 EEQIENEEE-ASFLLSLKSMKEVQNVLDNTTEPTITVRYDGRRVSLSTNDVETVMRVVDA 250 Query: 240 RFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ 299 FPDY+RV+P+ + L+++ R +++++ V+ + EN +++ + +P+ Sbjct: 251 EFPDYKRVIPETFKTKVVVSRKELRESLKRVMVIASKGSESVKFEIEENVMRLVSKSPDY 310 Query: 300 EEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAY 359 E + ++V G ++ I FN ++ DVL ++ E + M DS S QI Y Sbjct: 311 GEVVDEVEVQKEGEDLVIAFNPKFIEDVLKHIETEEIEMNFVDSTSPCQINPLDISGYLY 370 Query: 360 VVMPMRL 366 +VMP+RL Sbjct: 371 IVMPIRL 377 >2AVT-A nrPDB Length = 378 Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats. Identities = 86/375 (22%), Positives = 177/375 (47%), Gaps = 10/375 (2%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 ++F++ R + L + + +PIL ++ ++V ++LTG++ ++ + + + Sbjct: 2 IQFSINRTLFIHALNTTKRAISTKNAIPILSSIKIEVTSTGVTLTGSNGQISIENTIPVS 61 Query: 61 Q------PHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAA 114 PGA + A F +I LP+ + ++E ++++ SG+S +L Sbjct: 62 NENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQVVLTSGKSEITLKGKDVD 121 Query: 115 DFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGML-FETEGEELRTVATD 173 +P L + +E L +K +I T F+ + Q+ R L G+ + ++ + VATD Sbjct: 122 QYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPILTGVHIVLSNHKDFKAVATD 181 Query: 174 GHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFT 233 HR++ + + + V++P K + E + + V + I F Sbjct: 182 SHRMSQRLITLDNTSADFMVVLPSKSLREFSAVFTDDIETVEVFFSPSQILFRSEHISFY 241 Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKI 292 ++L++G +PD R+L + + L+ A RA ++SN G V+L +++N + Sbjct: 242 TRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERAFLISNATQNGTVKLEITQNHISA 301 Query: 293 TANNPEQEEAEEILD-VTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIED 351 N+PE + E LD V+ SG+++ I FN +Y+++ L A+K E V++ V + Sbjct: 302 HVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIESLKAIKSETVKIHFLSPVRPFTLTP 361 Query: 352 -AASQSAAYVVMPMR 365 +S ++ P+R Sbjct: 362 GDEEESFIQLITPVR 376 >2AWA-A nrPDB Length = 390 Score = 341 bits (874), Expect = 3e-94, Method: Composition-based stats. Identities = 80/373 (21%), Positives = 176/373 (47%), Gaps = 10/373 (2%) Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQ- 61 F++ + L+ L + + +PIL + + V + ++L G++ ++ + ++ Sbjct: 16 FSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNE 75 Query: 62 -----PHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADF 116 G+ + A F ++ LP+ ++E ++++ SG+S +L + + Sbjct: 76 DAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQY 135 Query: 117 PNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFET-EGEELRTVATDGH 175 P + + + L +K++I T F+ + Q+ R L G+ F + +EL+TVATD H Sbjct: 136 PRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSH 195 Query: 176 RLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSK 235 RL+ + + ++ V++P + + E + + + +N I + F ++ Sbjct: 196 RLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTR 255 Query: 236 LVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITA 294 L++G +PD R++P + + + L+Q+ RA +LS+ G V+L + + + Sbjct: 256 LLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHV 315 Query: 295 NNPEQEEAEEILDVTY-SGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAA 353 ++PE + E +D +G ++ I FN +Y++D L AL E V + +V + A Sbjct: 316 HSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPAD 375 Query: 354 -SQSAAYVVMPMR 365 + ++ P+R Sbjct: 376 TDEDFMQLITPVR 388 >3T0P-A nrPDB Length = 371 Score = 325 bits (832), Expect = 2e-89, Method: Composition-based stats. Identities = 85/369 (23%), Positives = 171/369 (46%), Gaps = 7/369 (1%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK + +LLK + VS + R T+ IL +L+ + + L D+E+ + + Sbjct: 2 MKLICSKANLLKGVNIVSKAVPTRTTMAILECILIDASANEIKLMANDMELGIE-TIIDG 60 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGE-RMLVRSGRSRFSLSTLPAADFPNL 119 E G + A+ F +I R LP+ ++ ++ + + ++ +++F++ DF + Sbjct: 61 TIEERGIIALDAKIFSEIVRKLPDN-DVTIETDASFKTVISCEKAKFNIIGKSGDDFSYI 119 Query: 120 DDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAV 179 + L Q T+K +I T FS+A D + G LFE E +LR V+ DGHR+++ Sbjct: 120 PYVERNESIVLSQFTLKEVIRQTIFSIADNDNNKLMTGELFEIEENKLRVVSLDGHRISI 179 Query: 180 CSMPIGQSLPSHSVIVPRKGVIELMRMLDG-GDNPLRVQIGSNNIRAHVGDFIFTSKLVD 238 + + S V+VP K + E+ +++ G D + + I +N+I + S+L++ Sbjct: 180 RYIEMKNHYDSKKVVVPGKTLQEISKIIPGSADEDVVIYITNNHIVFEFENTTVVSRLIE 239 Query: 239 GRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNP 297 G + ++L + D + L RA +L E + + + +++ +++ N+ Sbjct: 240 GEYFKIDQMLSSDYDTKVRINKRELLDCIDRATLLVKEGDKKPIIMNITDGNMELRINSF 299 Query: 298 EQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSA 357 E+I M IGFN + +D L + E V + + + + I+D Sbjct: 300 IGSMNEDIDIDKDGKDIM-IGFNPKFFIDALRVIDEEEVNLYMVNPKAPCFIKDDEG-KF 357 Query: 358 AYVVMPMRL 366 Y+++P+ Sbjct: 358 IYLILPVNF 366 >4TRT-A nrPDB Length = 368 Score = 315 bits (806), Expect = 2e-86, Method: Composition-based stats. Identities = 102/353 (28%), Positives = 175/353 (49%), Gaps = 12/353 (3%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK V ++ L + L + + R + P+L L ++ ++G L+L+GT+LE+++ V Sbjct: 2 MKANVTKKTLNEGLGLLERVIPSRSSNPLLTALKVETSEGGLTLSGTNLEIDLSCFVP-A 60 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + +P VPA F I R L G + ++L G+ + VRSG S F L T +P L Sbjct: 61 EVQQPENFVVPAHLFAQIVRNLG-GELVELELSGQELSVRSGGSDFKLQTGDIEAYPPL- 118 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVC 180 + ++ + +L + R + +++ +++ + G+ E GE R VA+DG+R+A+ Sbjct: 119 SFPAQADVSLDGGELSRAFSSVRYAASNEAFQAVFRGIKLEHHGESARVVASDGYRVAIR 178 Query: 181 SMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR 240 P S ++I+P + V EL+R+L G+ R G + KL+DG Sbjct: 179 DFP--ASGDGKNLIIPARSVDELIRVLKDGE--ARFTYGDGMLTVTTDRVKMNLKLLDGD 234 Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRG-VRLYVSENQLKITANNPEQ 299 FPDY RV+PK+ + LK+A R A+L+++ V VSE L++ A + Sbjct: 235 FPDYERVIPKDIKLQVTLPATALKEAVNRVAVLADKNANNRVEFLVSEGTLRLAAEG-DY 293 Query: 300 EEAEEILDVTYSGAE--MEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350 A++ L VT G E M + FN +VLD L + + ++ + S S Sbjct: 294 GRAQDTLSVTQGGTEQAMSLAFNARHVLDALGPIDGD-AELLFSGSTSPAIFR 345 >6DJ8-A nrPDB Length = 393 Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats. Identities = 74/384 (19%), Positives = 160/384 (41%), Gaps = 26/384 (6%) Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQP 62 F E ++ +++ G + R I LL++V L + TD + + +++V Sbjct: 15 FICETNQIMNEIEKAKGIILNRNMNDIWSALLIEVKKSNLIIKSTDRNIFFESTISIVSE 74 Query: 63 HEPGATTVPARKFFDICRGLPEGAEIAVQL---------------EGERMLVRSGRSRFS 107 + + A F+D + +I + E E FS Sbjct: 75 TD-FKVLINASNFYDAVKAFNFYKKIKIVFNENNSKLEIMGELNDEKEEYEDHLKEPTFS 133 Query: 108 LSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF-ETEGEE 166 + ++ +++ + Q + K++I FS + + LNG+ F + E + Sbjct: 134 YEEIENYNYDMVNE-DYTFGIEIKQKSFKKVINRIAFSAHLDESKNVLNGVYFSKDEDSK 192 Query: 167 LRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAH 226 L V+T+GHR+++C + + IVP K + ++ L G+ ++++ Sbjct: 193 LLLVSTNGHRMSICKTEVIVE-EDVNFIVPVK-IFNFLKHLMSGEGMVKIKFSDKKFYVE 250 Query: 227 VGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVS 286 ++ L++G +PDY+ ++PK +LK AR + + K R + L S Sbjct: 251 FDNYKIACSLINGNYPDYKSIIPKEQKNKSLVSLGILKDRLARVNLYVD-KSRKLVLTFS 309 Query: 287 ENQLKITANNPEQEEAEEIL----DVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTD 342 E QLK+ + E + Y GA+ + N+SY ++ ++ + + + + Sbjct: 310 ELQLKLLGEDLITGRKGEFFIKDPNYLYDGADEVMAINISYFVEAISVFETSKIEIQF-N 368 Query: 343 SVSSVQIEDAASQSAAYVVMPMRL 366 S + +++ + + + +++MPM L Sbjct: 369 SGNVLKLSEPENFNFTHLIMPMSL 392 >4S3I-A nrPDB Length = 384 Score = 259 bits (663), Expect = 1e-69, Method: Composition-based stats. Identities = 77/384 (20%), Positives = 164/384 (42%), Gaps = 28/384 (7%) Query: 1 MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALV 60 MK +V + L L+ + L + I ++ L+V L L +D ++ + + + Sbjct: 3 MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSDIGLKSYIFTQ 62 Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLD 120 + G T+ +KF DI L + + I ++ + + + ++ +S F L A +FP Sbjct: 63 SSDKEGVGTINGKKFLDIISCLKD-SNIILETKDDSLAIKQNKSSFKLPMFDADEFPEFP 121 Query: 121 DWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGML--FETEGEELRTVATDGHRLA 178 +V + + + + + L G+L F+ + + L V TD RL+ Sbjct: 122 VIDPKVSIEVNAPFLVDAFKKIAPVIEQTSHKRELAGILMQFDQKHQTLSVVGTDTKRLS 181 Query: 179 VCSMP---IGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGD--FIFT 233 + I + S I+P++ ++E++++ S+ + A + + F Sbjct: 182 YTQLEKISIHSTEEDISCILPKRALLEILKLFYEN-----FSFKSDGMLAVIENEMHTFF 236 Query: 234 SKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293 +KL+DG +PDY+++LPK G + K++ + LS+ ++L + +N Sbjct: 237 TKLIDGNYPDYQKILPKEYISSFTLGKEEFKESIKLCSSLSS----TIKLTLEKNNALFE 292 Query: 294 ANNPEQEEAEEILDVTYSGAEMEIGF----NVSYVLDVLNALKCENVRMMLTDSVSSVQI 349 + + E E + G ++E F N + L+ LNAL + + S I Sbjct: 293 SLDSEHSETAKTSVEIEKGLDIEKAFHLGVNAKFFLEALNALGTTQFVLRCNEPSSPFLI 352 Query: 350 EDAASQSAAY-------VVMPMRL 366 +++ + ++ ++MP+ L Sbjct: 353 QESLDEKQSHLNAKISTLMMPITL 376 >3K4X-A nrPDB Length = 798 Score = 51.6 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 58/398 (14%), Positives = 132/398 (33%), Gaps = 55/398 (13%) Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVAD----GTLSLTGTDLEMEMVARVA 58 ++ K ++ +S + + G++ + ++ME Sbjct: 410 LSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPF-VDMEHPETSI 468 Query: 59 LVQPHEPGATTVPARKFFDICR--GLPEGAEIAVQLEGERM---LVRSGRSRFSLSTLPA 113 ++ +P T A+ DI + L + I + E + ++SG +F L+ Sbjct: 469 KLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLA---- 524 Query: 114 ADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATD 173 P +D S + + A + EA+ F + + + F+ + + + A D Sbjct: 525 ---PKFNDEGSNSQASNSGALEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVD 581 Query: 174 GHRLAVCSMPIGQSL-----PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIR 224 R+ + S+ IG H V + + L ++L G+N + + ++I Sbjct: 582 DSRVLLVSLEIGVEAFQEYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSII 640 Query: 225 AHVGDFI------FTSKL--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE 276 D ++ KL +D F + D L + + LS+ Sbjct: 641 LLFEDTKKDRIAEYSLKLMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD- 696 Query: 277 KFRGVRLYVSENQLKITANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVL 325 + + +++ +K A+ E E +++ F Y+L Sbjct: 697 ---SINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLL 753 Query: 326 DVLNALK-CENVRMMLTDSVSSVQIEDAASQSAAYVVM 362 D++ + V + L+ S + + + Sbjct: 754 DIIKGSSLSDRVGIRLS-SEAPALFQFDLKSGFLQFFL 790 Score = 51.6 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 58/398 (14%), Positives = 131/398 (32%), Gaps = 55/398 (13%) Query: 3 FTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVAD----GTLSLTGTDLEMEMVARVA 58 ++ K ++ +S + + G++ + ++ME Sbjct: 143 LSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPF-VDMEHPETSI 201 Query: 59 LVQPHEPGATTVPARKFFDICR--GLPEGAEIAVQLEGERM---LVRSGRSRFSLSTLPA 113 ++ +P T A+ DI + L + I + E + ++SG +F L+ Sbjct: 202 KLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLA---- 257 Query: 114 ADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATD 173 P +D S + A + EA+ F + + + F+ + + + A D Sbjct: 258 ---PKFNDEGSNSQSNGSGALEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVD 314 Query: 174 GHRLAVCSMPIGQSL-----PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIR 224 R+ + S+ IG H V + + L ++L G+N + + ++I Sbjct: 315 DSRVLLVSLEIGVEAFQEYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSII 373 Query: 225 AHVGDFI------FTSKL--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE 276 D ++ KL +D F + D L + + LS+ Sbjct: 374 LLFEDTKKDRIAEYSLKLMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD- 429 Query: 277 KFRGVRLYVSENQLKITANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVL 325 + + +++ +K A+ E E +++ F Y+L Sbjct: 430 ---SINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLL 486 Query: 326 DVLNALK-CENVRMMLTDSVSSVQIEDAASQSAAYVVM 362 D++ + V + L+ S + + + Sbjct: 487 DIIKGSSLSDRVGIRLS-SEAPALFQFDLKSGFLQFFL 523 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 37/261 (14%), Positives = 84/261 (32%), Gaps = 47/261 (18%) Query: 131 PQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSL-- 188 + KR+I + + + F+ + + + A D R+ + S+ IG Sbjct: 14 EASLFKRII---------DGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQ 64 Query: 189 ---PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIRAHVGDFI------FTSK 235 H V + + L ++L G+N + + ++I D ++ K Sbjct: 65 EYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLK 123 Query: 236 L--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293 L +D F + D L + + LS+ + + +++ +K Sbjct: 124 LMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD----SINIMITKETIKFV 176 Query: 294 ANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVLDVLNALK-CENVRMMLT 341 A+ E E +++ F Y+LD++ + V + L+ Sbjct: 177 ADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLS 236 Query: 342 DSVSSVQIEDAASQSAAYVVM 362 S + + + Sbjct: 237 -SEAPALFQFDLKSGFLQFFL 256 >1AZW-A nrPDB Length = 313 Score = 41.5 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 38/97 (39%), Gaps = 8/97 (8%) Query: 143 QFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIE 202 + A + Y++NG FE E + LR D HR+A +P + V+ P + + Sbjct: 223 ALAFARIENHYFVNGGFFEVEDQLLR----DAHRIA--DIPGVIVHGRYDVVCPLQSAWD 276 Query: 203 LMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDG 239 L + L++ S + + + DG Sbjct: 277 LHKAWP--KAQLQISPASGHSAFEPENVDALVRATDG 311 >5ZUT-A nrPDB Length = 289 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 37/261 (14%), Positives = 84/261 (32%), Gaps = 47/261 (18%) Query: 131 PQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSL-- 188 + KR+I + + + F+ + + + A D R+ + S+ IG Sbjct: 8 EASLFKRII---------DGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQ 58 Query: 189 ---PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIRAHVGDFI------FTSK 235 H V + + L ++L G+N + + ++I D ++ K Sbjct: 59 EYRCDHPVTL-GMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLK 117 Query: 236 L--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293 L +D F + D L + + LS+ + + +++ +K Sbjct: 118 LMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD----SINIMITKETIKFV 170 Query: 294 ANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVLDVLNALK-CENVRMMLT 341 A+ E E +++ F Y+LD++ + V + L+ Sbjct: 171 ADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLS 230 Query: 342 DSVSSVQIEDAASQSAAYVVM 362 S + + + Sbjct: 231 -SEAPALFQFDLKSGFLQFFL 250 >4L60-A nrPDB Length = 256 Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 37/261 (14%), Positives = 84/261 (32%), Gaps = 47/261 (18%) Query: 131 PQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSL-- 188 + KR+I + + + F+ + + + A D R+ + S+ IG Sbjct: 8 EASLFKRII---------DGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQ 58 Query: 189 ---PSHSVIVPRKGVIELMRMLDGGDNPLRVQI----GSNNIRAHVGDFI------FTSK 235 H V + + L ++L G+N + + ++I D ++ K Sbjct: 59 EYRCDHPVTL-GMDLTSLSKILRRGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLK 117 Query: 236 L--VDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKIT 293 L +D F + D L + + LS+ + + +++ +K Sbjct: 118 LMDIDADFLKIEEL---QYDSTLSLPSSEFSKIVRDLSQLSD----SINIMITKETIKFV 170 Query: 294 ANNPEQE-----------EAEEILDVTYSGAEMEIGFNVSYVLDVLNALK-CENVRMMLT 341 A+ E E +++ F Y+LD++ + V + L+ Sbjct: 171 ADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLS 230 Query: 342 DSVSSVQIEDAASQSAAYVVM 362 S + + + Sbjct: 231 -SEAPALFQFDLKSGFLQFFL 250 >1RXZ-A nrPDB Length = 245 Score = 35.8 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 41/122 (33%), Gaps = 15/122 (12%) Query: 61 QPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGER-MLVRSGRSRFSLSTLPAADF--- 116 E V + FDI + + + + +E E + V+ G + ++ + + Sbjct: 60 NIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVKFGSVEYKVALIDPSAIRKE 119 Query: 117 PNLDDWQSEVEFTLPQATMKRLI-------EATQFSMAHQDVRYYLNG----MLFETEGE 165 P + + + + + K+ I + F + R G ++F Sbjct: 120 PRIPELELPAKIVMDAGEFKKAIAAADKISDQVIFRSDKEGFRIEAKGDVDSIVFHMTET 179 Query: 166 EL 167 EL Sbjct: 180 EL 181 >1V6S-A nrPDB Length = 390 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 46/140 (32%), Gaps = 9/140 (6%) Query: 111 LPAADFPNLDDWQSEVEFTLPQATMKR--LIEATQFSMAHQDVRYYLNGMLFETEGEELR 168 LP A F E L+E +F + L+ + Sbjct: 81 LPEARFAPFPPGSEEARREAEALRPGEVLLLENVRFEPGEEKNDPELSARYARLGEAFVL 140 Query: 169 TVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVG 228 HR + + + LP+++ + K V L R+L + P V +G + +G Sbjct: 141 DAFGSAHRAHASVVGVARLLPAYAGFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIG 200 Query: 229 DFIFTSKLVDGRFPDYRRVL 248 +++ P R+L Sbjct: 201 -------VIESLLPRIDRLL 213 >5XNX-A nrPDB Length = 394 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 50/114 (43%), Gaps = 15/114 (13%) Query: 165 EELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIR 224 E L +A HRL + S+ S +++ P+K E++R++ G + +R Sbjct: 167 ETLEVIAPLAHRLGMASVKWELEDLSFAILHPKK-YEEIVRLVAGRAPSRDTYLA--KVR 223 Query: 225 AHVGDFIFTSKL---VDGRFPD-----YRRVLPKNP---DKHLEAGCDLLKQAF 267 A + + + SK+ V+GR P Y++++ K D H G +L Sbjct: 224 AEIVNTLTASKIKATVEGR-PKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEI 276 >6G1M-A nrPDB Length = 338 Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 33/88 (37%), Gaps = 1/88 (1%) Query: 241 FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQE 300 +PD ++ + + + I+S K + ++E + +P+ Sbjct: 57 YPDPITMVKQTDPDLVVIATNSFISVVKD-QIISILKENKNVITIAEEMAFPFSKDPKAA 115 Query: 301 EAEEILDVTYSGAEMEIGFNVSYVLDVL 328 + + ++ + + G N +VLD L Sbjct: 116 NEIDTVAKDHNVSVLGTGVNPGFVLDTL 143 >4NV8-A nrPDB Length = 312 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 26/96 (27%), Gaps = 16/96 (16%) Query: 116 FPNLDDWQSE---VEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172 F ++ + + L + + + + A D RY L G Sbjct: 213 FDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLSIHHL------- 265 Query: 173 DGHRLAVCSMPIGQSLPS-----HSVIVPRKGVIEL 203 G R + L +I+P + E Sbjct: 266 -GGRTEQTEIATAADLADTLQGLLGIIIPDRTAFEA 300 >2BSZ-A nrPDB Length = 278 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 26/96 (27%), Gaps = 16/96 (16%) Query: 116 FPNLDDWQSE---VEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVAT 172 F ++ + + L + + + + A D RY L G Sbjct: 179 FDLQPQYEVDYSVTNYFLSTSPTSHFLSSVIAARAAPDRRYALRGNRLSIHHL------- 231 Query: 173 DGHRLAVCSMPIGQSLPS-----HSVIVPRKGVIEL 203 G R + L +I+P + E Sbjct: 232 -GGRTEQTEIATAADLADTLQGLLGIIIPDRTAFEA 266 >2R5V-A nrPDB Length = 357 Score = 29.6 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 27/80 (33%), Gaps = 4/80 (5%) Query: 263 LKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ----EEAEEILDVTYSGAEMEIG 318 +Q F ++ + + + + +T P++ + +E L I Sbjct: 184 FRQIFDEHIVVGAQAMNSTVVQSASGAVTLTLIEPDRNADPGQIDEFLKDHQGAGVQHIA 243 Query: 319 FNVSYVLDVLNALKCENVRM 338 FN + + + AL V Sbjct: 244 FNSNDAVRAVKALSERGVEF 263 >3IBD-A nrPDB Length = 476 Score = 29.2 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 11/33 (33%) Query: 318 GFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350 FN + LD ALK + + E Sbjct: 388 AFNPDHFLDANGALKKTEAFIPFSLGKRICLGE 420 >5E58-A nrPDB Length = 493 Score = 29.2 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 11/32 (34%) Query: 319 FNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350 FN + LD ALK M + E Sbjct: 408 FNPDHFLDANGALKKSEAFMPFSIGKRICLGE 439 >5E0E-A nrPDB Length = 463 Score = 29.2 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 11/32 (34%) Query: 319 FNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350 FN + LD ALK M + E Sbjct: 380 FNPDHFLDANGALKKSEAFMPFSIGKRICLGE 411 >5A6D-A nrPDB Length = 249 Score = 28.4 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 40/96 (41%), Gaps = 11/96 (11%) Query: 252 PDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYS 311 + ++LK+A A+++S+ ++ E++ + A E ++ Sbjct: 130 FTAKVVLLGEVLKEAIKDASLVSD----SLKFIAKEDEFTMKAEGETNEVEIKLTLEDEG 185 Query: 312 GAEMEI------GFNVSYVLDVLNAL-KCENVRMML 340 ++E+ + +SY+ D++ + K + V + Sbjct: 186 LLDLEVEEETRSAYGISYLADMVKGIGKADEVTLRF 221 >2IX2-C nrPDB Length = 259 Score = 28.4 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 41/113 (36%), Gaps = 10/113 (8%) Query: 244 YRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQ---- 299 + R + K + +LK A L +E L ++ +++ A + Sbjct: 7 FERNIRLINMKVVYDDVRVLKDIIQALARLVDEA----VLKFKQDSVELVALDRAHISLI 62 Query: 300 --EEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIE 350 E+ E + GFN Y++ +L K + + ++S SV I Sbjct: 63 SVNLPREMFKEYDVNDEFKFGFNTQYLMKILKVAKRKEAIEIASESPDSVIIN 115 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.138 0.328 Lambda K H 0.267 0.0427 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,617,679 Number of Sequences: 36641 Number of extensions: 413959 Number of successful extensions: 1452 Number of sequences better than 10.0: 42 Number of HSP's better than 10.0 without gapping: 45 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 1238 Number of HSP's gapped (non-prelim): 82 length of query: 366 length of database: 10,336,785 effective HSP length: 98 effective length of query: 268 effective length of database: 6,745,967 effective search space: 1807919156 effective search space used: 1807919156 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.7 bits)