BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0A8N5 (505 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1LYL-A nrPDB 1036 0.0 1BBU-A nrPDB 937 0.0 4EX5-A nrPDB 593 e-170 3A74-A nrPDB 544 e-155 6CHD-A nrPDB 412 e-115 6ILH-A nrPDB 406 e-114 5HGQ-A nrPDB 376 e-104 4YCV-A nrPDB 370 e-103 5ELO-A nrPDB 359 2e-99 4UP8-A nrPDB 355 3e-98 6AQG-A nrPDB 346 1e-95 6NRZ-A nrPDB 335 2e-92 6AQH-A nrPDB 333 8e-92 3G1Z-A nrPDB 154 6e-38 3A5Z-A nrPDB 147 1e-35 1WYD-A nrPDB 127 1e-29 1ASZ-A nrPDB 116 2e-26 3I7F-A nrPDB 115 4e-26 3NEM-A nrPDB 106 2e-23 1N9W-A nrPDB 105 4e-23 4J15-A nrPDB 105 6e-23 4WJ3-M nrPDB 94 1e-19 4RMF-A nrPDB 92 5e-19 6OD8-A nrPDB 91 1e-18 1IL2-A nrPDB 91 1e-18 5W25-A nrPDB 90 2e-18 1X54-A nrPDB 85 7e-17 1EFW-A nrPDB 85 7e-17 4AH6-A nrPDB 80 2e-15 3M4P-A nrPDB 66 3e-11 5ZG8-A nrPDB 62 4e-10 5XIX-A nrPDB 60 2e-09 2XGT-A nrPDB 55 1e-07 2ZNJ-A nrPDB 42 5e-04 6JP2-A nrPDB 40 0.003 3P8T-A nrPDB 39 0.006 1NNH-A nrPDB 38 0.013 3VQX-A nrPDB 36 0.045 3D2D-A nrPDB 32 0.84 2PME-A nrPDB 30 1.8 3QIB-B nrPDB 30 2.6 4P2O-B nrPDB 30 2.9 5GY2-A nrPDB 30 3.1 3V44-A nrPDB 30 3.2 4MNK-A nrPDB 29 4.8 1YC9-A nrPDB 28 8.5 >1LYL-A nrPDB Length = 504 Score = 1036 bits (2680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 504/504 (100%), Positives = 504/504 (100%) Query: 2 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL 61 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL Sbjct: 1 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL 60 Query: 62 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI 121 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI Sbjct: 61 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI 120 Query: 122 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR 181 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR Sbjct: 121 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR 180 Query: 182 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE 241 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE Sbjct: 181 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE 240 Query: 242 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 301 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL Sbjct: 241 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 300 Query: 302 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT 361 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT Sbjct: 301 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT 360 Query: 362 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 421 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR Sbjct: 361 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 420 Query: 422 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR 481 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR Sbjct: 421 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR 480 Query: 482 MIMLFTNSHTIRDVILFPAMRPQK 505 MIMLFTNSHTIRDVILFPAMRPQK Sbjct: 481 MIMLFTNSHTIRDVILFPAMRPQK 504 >1BBU-A nrPDB Length = 504 Score = 937 bits (2422), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/504 (88%), Positives = 478/504 (94%) Query: 2 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL 61 SEQ +GA+ +D N+EL+ RREKLA LR+QG+AFPNDFRRDHTSDQLH EFD K+N+EL Sbjct: 1 SEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDHTSDQLHAEFDGKENEEL 60 Query: 62 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI 121 E+LNIEV+VAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD LPEGVYN+QFKKWDLGDI Sbjct: 61 EALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDI 120 Query: 122 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR 181 +GA+G LFKT+TGELSIHCTELRLLTKALRPLPDKFHGLQDQE RYRQRYLDLI+ND+SR Sbjct: 121 LGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESR 180 Query: 182 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE 241 TF VRS+IL+ IRQFMV RGFMEVETPMMQVIPGGA+ARPFITHHNALDLDMYLRIAPE Sbjct: 181 NTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPE 240 Query: 242 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 301 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADY DLIELTESLFRTL Sbjct: 241 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTL 300 Query: 302 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT 361 AQ++LG T+VTYG+ DFGKPFEKLTMREAIKKYRPETDMADLDNFD+AKA+AESIGI Sbjct: 301 AQDILGKTEVTYGDVTLDFGKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIH 360 Query: 362 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 421 VEKSWGLGRIVTEIF+EVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR Sbjct: 361 VEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 420 Query: 422 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR 481 EIGNGFSELNDAEDQA+RF +QV AK AGDDEAMFYDEDYVTALE+GLPPTAGLGIGIDR Sbjct: 421 EIGNGFSELNDAEDQAQRFLDQVAAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDR 480 Query: 482 MIMLFTNSHTIRDVILFPAMRPQK 505 M+MLFTNSHTIRDVILFPAMRP K Sbjct: 481 MVMLFTNSHTIRDVILFPAMRPVK 504 >4EX5-A nrPDB Length = 529 Score = 593 bits (1528), Expect = e-170, Method: Compositional matrix adjust. Identities = 289/506 (57%), Positives = 365/506 (72%), Gaps = 5/506 (0%) Query: 1 MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQE 60 M+E A A D N + RR+KL ALR QG+A+PNDF+ H + L + D + Sbjct: 22 MTEPIQPQAAVAADENQIVAERRDKLRALRDQGIAYPNDFQPTHHAADLQTAYADADKEA 81 Query: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGD 120 LE+ ++EV++AGRMM +R+MGKASF T+QD G+IQ +V + Y D FKKWDLGD Sbjct: 82 LEAKSLEVAIAGRMMLKRVMGKASFATVQDGSGQIQFFVTPADVGAETY-DAFKKWDLGD 140 Query: 121 IIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKS 180 I+ ARG LF+T GELS+ CT+LRLL KALRPLPDKFHGL DQE RYRQRY+DLI ++ Sbjct: 141 IVAARGVLFRTNKGELSVKCTQLRLLAKALRPLPDKFHGLADQETRYRQRYVDLIVTPET 200 Query: 181 RQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAP 240 R TF R+K +A+IR+FM FMEVETPM+ IPGGA+A+PF+THHNALD++M+LRIAP Sbjct: 201 RTTFRARTKAIASIRKFMGDADFMEVETPMLHPIPGGAAAKPFVTHHNALDMEMFLRIAP 260 Query: 241 ELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRT 300 ELYLKRL+VGGFERVFEINRNFRNEG+S RHNPEFTMME Y AY DY L++ TE L R Sbjct: 261 ELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTERLIRQ 320 Query: 301 LAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGI 360 A + LGT + Y D +PF +LT+ +AI+KY P L + ++ + +G+ Sbjct: 321 AAVDALGTATIQYQGRELDLAQPFHRLTITQAIQKYAPSYTDGQLSDDAFLRSELKRLGV 380 Query: 361 TVEK----SWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEF 416 V + + G+G + +F+E AEA L +PTFI +YP EVSPLAR +D IT+RFE Sbjct: 381 DVTQPAFLNAGIGALQLALFEETAEAQLWEPTFIIDYPIEVSPLARESDTVAGITERFEL 440 Query: 417 FIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLG 476 FI GREI NGFSELND EDQA RF++QV K AGD+EAMF+D DY+ ALEYG+PPT G G Sbjct: 441 FITGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCG 500 Query: 477 IGIDRMIMLFTNSHTIRDVILFPAMR 502 IGIDR++ML T+S TIRDV+LFP +R Sbjct: 501 IGIDRLVMLLTDSPTIRDVLLFPHLR 526 >3A74-A nrPDB Length = 493 Score = 544 bits (1402), Expect = e-155, Method: Compositional matrix adjust. Identities = 270/490 (55%), Positives = 356/490 (72%), Gaps = 3/490 (0%) Query: 14 DFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAG 72 + ND+LR RREKL + + GV F F R H +++L E + +ELE IEV+VAG Sbjct: 4 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAG 63 Query: 73 RMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQ 132 R+MT+R MGKA F +QDV G+IQ+YV +D + E Y + FK DLGDI+G RGT+FKT+ Sbjct: 64 RIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQY-ELFKISDLGDIVGVRGTMFKTK 122 Query: 133 TGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILA 192 GELSI + LTKALRPLP+K+HGL+D E RYRQRYLDLI N +S++TF+ RS I+ Sbjct: 123 VGELSIKVSSYEFLTKALRPLPEKYHGLKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQ 182 Query: 193 AIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGF 252 ++R+++ + G++EVETPMM + GGA+ARPFITHHNALD+ +Y+RIA EL+LKRL+VGG Sbjct: 183 SMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGL 242 Query: 253 ERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVT 312 E+V+EI R FRNEGIS RHNPEFTM+ELY AYAD+ D+++LTE+L +A EVLGTTK+ Sbjct: 243 EKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQ 302 Query: 313 YGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIV 372 YGEH+ D + +L M +AIK+Y D + + A+ LA+ G+ V G IV Sbjct: 303 YGEHLVDLTPEWRRLHMVDAIKEYVG-VDFWRQMSDEEARELAKEHGVEVAPHMTFGHIV 361 Query: 373 TEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELND 432 E F++ E LIQPTFI +P E+SPLA++N +P TDRFE FI GRE N F+ELND Sbjct: 362 NEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELND 421 Query: 433 AEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTI 492 DQ +RF+EQ+ + G+DEA DED++ ALEYG+PPT GLGIG+DR++ML TNS +I Sbjct: 422 PIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSI 481 Query: 493 RDVILFPAMR 502 RDV+LFP MR Sbjct: 482 RDVLLFPQMR 491 >6CHD-A nrPDB Length = 597 Score = 412 bits (1059), Expect = e-115, Method: Compositional matrix adjust. Identities = 228/516 (44%), Positives = 319/516 (61%), Gaps = 30/516 (5%) Query: 11 EAIDFNDELRNRREKLAALRQQGV-AFPNDFRRDHT-SDQLHEEFDAKDNQELESLNIEV 68 E++D N + R + + L+ G +P+ F D + +D + + + L +I + Sbjct: 69 ESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHL--TDITL 126 Query: 69 SVAGRMMTRRIMG-KASFVTLQDVGGRIQLYV-ARDSLPEGVYNDQFKKWDLGDIIGARG 126 VAGR+ +R G K F L+ G ++Q+ +R+ E + K GDIIG +G Sbjct: 127 KVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQG 186 Query: 127 TLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVV 186 KT+ GELSI E+ LL+ L LP GL+D+E RYRQRYLDLI ND RQ F++ Sbjct: 187 NPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFII 246 Query: 187 RSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKR 246 RSKI+ IR F+ GF+E+ETPMM +IPGGA A+PFIT+HN LD+++Y+RIAPELY K Sbjct: 247 RSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKM 306 Query: 247 LVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVL 306 LVVGG +RV+EI R FRNEGI + HNPEFT E YMAYADYHDL+E+TE + + + + Sbjct: 307 LVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHIT 366 Query: 307 GTTKVTYGE-------HVFDFGKPFEKLTMREAIKK----YRPETDMAD-------LDNF 348 G+ KVTY + DF PF ++ M E ++K PET++ + LD+ Sbjct: 367 GSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDI 426 Query: 349 DAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNP 408 AKA + R++ ++ E E I PTFI ++P +SPLA+ + Sbjct: 427 CVAKA------VECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKE 480 Query: 409 EITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYG 468 +T+RFE F+ +EI N ++ELND Q + F+EQ AKAAGDDEAMF DE++ TALEYG Sbjct: 481 GLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYG 540 Query: 469 LPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQ 504 LPPTAG G+GIDR+ M T+S+ I++V+LFPAM+P+ Sbjct: 541 LPPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPE 576 >6ILH-A nrPDB Length = 521 Score = 406 bits (1044), Expect = e-114, Method: Compositional matrix adjust. Identities = 226/515 (43%), Positives = 317/515 (61%), Gaps = 30/515 (5%) Query: 12 AIDFNDELRNRREKLAALRQQGV-AFPNDFRRDHT-SDQLHEEFDAKDNQELESLNIEVS 69 ++D N + R + + L+ G +P+ F D + +D + + + L +I + Sbjct: 2 SVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLT--DITLK 59 Query: 70 VAGRMMTRRIMG-KASFVTLQDVGGRIQLYV-ARDSLPEGVYNDQFKKWDLGDIIGARGT 127 VAGR+ +R G K F L+ G ++Q+ +R+ E + K GDIIG +G Sbjct: 60 VAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGN 119 Query: 128 LFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVR 187 KT+ GELSI E+ LL+ L LP GL+D+E RYRQRYLDLI ND RQ F++R Sbjct: 120 PGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIR 179 Query: 188 SKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRL 247 SKI+ IR F+ GF+E+ETPMM +IPGGA A+PFIT+HN LD+++Y+RIAPELY K L Sbjct: 180 SKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKML 239 Query: 248 VVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLG 307 VVGG +RV+EI R FRNEGI + HNPEFT E YMAYADYHD +E+TE + + + + G Sbjct: 240 VVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDHMEITEKMVSGMVKHITG 299 Query: 308 TTKVTYGE-------HVFDFGKPFEKLTMREAIKK----YRPETDMAD-------LDNFD 349 + KVTY + DF PF ++ M E ++K PET++ + LD+ Sbjct: 300 SYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDIC 359 Query: 350 AAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPE 409 AKA + R++ ++ E E I PTFI ++P +SPLA+ + Sbjct: 360 VAKA------VECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEG 413 Query: 410 ITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGL 469 +T+RFE F+ +EI N ++ELND Q + F+EQ AKAAGDDEAMF DE++ TALEYGL Sbjct: 414 LTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGL 473 Query: 470 PPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQ 504 PPTAG G+GIDR+ M T+S+ I++V+LFPAM+P+ Sbjct: 474 PPTAGWGMGIDRVAMFLTDSNNIKEVLLFPAMKPE 508 >5HGQ-A nrPDB Length = 524 Score = 376 bits (965), Expect = e-104, Method: Compositional matrix adjust. Identities = 215/493 (43%), Positives = 298/493 (60%), Gaps = 23/493 (4%) Query: 30 RQQGV-AFPNDFRRDHTSDQLHEEFDAKDNQELESL---NIEVSVAGRMMTRR-IMGKAS 84 R +G+ +P+ F H S L +F AK N + + +I SVAGR+ ++R GK Sbjct: 22 RSKGINPYPHKF---HVSISL-ADFIAKYNSLEKDVILNDIVQSVAGRVFSKRESGGKLI 77 Query: 85 FVTLQDVGGRIQLYV-ARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTEL 143 F L G R+Q+ AR + +++ + GDIIG G ++++GELSI E+ Sbjct: 78 FYDLHGEGTRLQVLANARFHSGDEAFDNLHDRIKRGDIIGVNGYPARSKSGELSIIPYEI 137 Query: 144 RLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGF 203 LT L LP GL++QE RYR RYLDLI N + FV RS++++ +R+++ GF Sbjct: 138 IQLTPCLHMLPHTHFGLKNQETRYRMRYLDLIMNPDVKNRFVTRSRMISFLRRYLDNLGF 197 Query: 204 MEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR 263 +EVETPMM +I GGA+A+PFITHHN LD+D+YLR+APELYLK LVVGG +RV+EI R FR Sbjct: 198 LEVETPMMNLIAGGATAKPFITHHNDLDMDLYLRVAPELYLKMLVVGGIDRVYEIGRVFR 257 Query: 264 NEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGE-------- 315 NEGI HNPEFT E YMAYADY DL+++TE + + + GT K+ Y Sbjct: 258 NEGIDQTHNPEFTSCEFYMAYADYEDLMKITEDMLARMVYYMHGTYKIQYHPNGIVENPV 317 Query: 316 HVFDFGKPFEKLTMREAIKKYR----PETDMADLDNFDA-AKALAESIGITVEKSWGLGR 370 + DF PF K+ + + +++ P D D D + LA + R Sbjct: 318 YEVDFTPPFRKVNIYDGLQEKLGIQFPPADTLDTDEANKFFDKLAVENNVECPAPRTTAR 377 Query: 371 IVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSEL 430 ++ ++ E E I PTF+T +P +SPLA+ + P +T+RFE F+ +EI N ++EL Sbjct: 378 LLDKLIGEFLEPTFISPTFLTGHPQIMSPLAKWHRSIPGLTERFELFVVTKEIVNAYTEL 437 Query: 431 NDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSH 490 ND Q RF EQ K AGDDEA DE+Y TALEYGLPPTAG G+GIDR+ M+ T+S+ Sbjct: 438 NDPLTQRLRFDEQAKQKQAGDDEAQNIDENYCTALEYGLPPTAGWGMGIDRLAMILTDSN 497 Query: 491 TIRDVILFPAMRP 503 I++V+ FPAMRP Sbjct: 498 NIKEVLFFPAMRP 510 >4YCV-A nrPDB Length = 516 Score = 370 bits (951), Expect = e-103, Method: Compositional matrix adjust. Identities = 215/505 (42%), Positives = 304/505 (60%), Gaps = 27/505 (5%) Query: 19 LRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEF-DAKDNQELESLNIEVSVAGRMMT 76 NR + + + +G+ +P+ F R + + E++ D + + LE + +++ GR+M Sbjct: 9 FENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLE--DTILNITGRIMR 66 Query: 77 RRIMG-KASFVTLQDVGGRIQLYV--ARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQT 133 G K F L G +IQ+ + + +G + + + K GDI+G G K++ Sbjct: 67 VSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKK 126 Query: 134 GELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAA 193 GELSI E LL+ L LP K+ GL+D E+RYRQRYLDL+ N+ SR TFV R+KI+ Sbjct: 127 GELSIFPKETILLSACLHMLPMKY-GLKDTEIRYRQRYLDLLINESSRHTFVTRTKIINF 185 Query: 194 IRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFE 253 +R F+ RGF EVETPMM +I GGA+ARPFITHHN LDLD+YLRIA EL LK L+VGG + Sbjct: 186 LRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGID 245 Query: 254 RVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTY 313 +V+EI + FRNEGI HNPEFT E Y AYADY+DLI+ +E F L + GT K++Y Sbjct: 246 KVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISY 305 Query: 314 GEH-------VFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSW 366 + DF P+ K+++ E I+K T+ FD+ + + + I I E Sbjct: 306 NKDGPENQPIEIDFTPPYPKVSIVEEIEKV---TNTILEQPFDSNETIEKMINIIKEHKI 362 Query: 367 GLGRIVT--EIFDEVAEAHLIQ------PTFITEYPAEVSPLARRNDVNPEITDRFEFFI 418 L T ++ D++A +H I+ P FI E+P +SPLA+ + P +T+R E FI Sbjct: 363 ELPNPPTAAKLLDQLA-SHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEMFI 421 Query: 419 GGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIG 478 G+E+ N ++ELND Q E F+ Q + GD EA D + T+LEYGLPPT GLG+G Sbjct: 422 CGKEVLNAYTELNDPFKQKECFKLQQKDREKGDTEAAQLDSAFCTSLEYGLPPTGGLGLG 481 Query: 479 IDRMIMLFTNSHTIRDVILFPAMRP 503 IDR+ M TN ++I+DVILFP MRP Sbjct: 482 IDRITMFLTNKNSIKDVILFPTMRP 506 >5ELO-A nrPDB Length = 535 Score = 359 bits (922), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 194/496 (39%), Positives = 299/496 (60%), Gaps = 15/496 (3%) Query: 21 NRREKLAALRQQGVAF-PNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMT-RR 78 NR + + ++ G F P+ F+ + ++ +N ++ + +S++GR+ + R Sbjct: 26 NRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYIDK-DTTLSLSGRVTSIRS 84 Query: 79 IMGKASFVTLQDVGGRIQLY--VARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGEL 136 K F + ++Q+ + + G ++ + GD++G G K++ GEL Sbjct: 85 SSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKRGEL 144 Query: 137 SIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQ 196 S+ + LL+ LP GL+DQEVRYRQRYLDL+ N++SR+ F +RS+ + IR Sbjct: 145 SLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKYIRN 204 Query: 197 FMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVF 256 + GF+EVETPM+ +I GGA+ARPFIT+HN L+ +Y+RIAPELYLK+L+VGG ++V+ Sbjct: 205 YFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLDKVY 264 Query: 257 EINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTY--- 313 EI +NFRNEGI + HNPEFT ME YMAYADY+DL++LTE L L E+ G+ K+ Y Sbjct: 265 EIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPYHPD 324 Query: 314 ---GEHV-FDFGKPFEKLTMREAIKKYRPETDMADLD---NFDAAKALAESIGITVEKSW 366 G+ + DF P+++ + E I+ E LD N D + E I + Sbjct: 325 GPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELPHPR 384 Query: 367 GLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNG 426 +++ ++ E P+FI ++P +SPLA+ + PE+T+RFE F+ G+E+ N Sbjct: 385 TAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKELCNA 444 Query: 427 FSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLF 486 ++ELN+ Q + F++Q +AKA+GD EA DE + ALE+GLPPT G G+GIDR+IM Sbjct: 445 YTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLIMFL 504 Query: 487 TNSHTIRDVILFPAMR 502 + + I++VILFPAMR Sbjct: 505 ADKNNIKEVILFPAMR 520 >4UP8-A nrPDB Length = 777 Score = 355 bits (911), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 201/517 (38%), Positives = 289/517 (55%), Gaps = 88/517 (17%) Query: 68 VSVAGRMMTRRIMGKA-SFVTLQDVGGRIQLYVARD---------SLPEGVYNDQFKKWD 117 VSVAGR++++R A F+ L D ++Q+ + + SL + +Y Sbjct: 62 VSVAGRVLSKRSSSSALMFIDLHDSQTKLQIMLNKSAYENKEDFVSLTKMIYR------- 114 Query: 118 LGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIAN 177 GDI G G +T+TGELS+ +L+ L LP +GL DQE R+R+RYLDLI N Sbjct: 115 -GDICGFTGHPTRTKTGELSLIPISGMILSPCLHMLPSMHYGLGDQETRFRKRYLDLIVN 173 Query: 178 DKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLR 237 +S + FV+R+K++ A+R+++ +GF+EVETP++ IPGGA+ARPFITHHN LD+ MY+R Sbjct: 174 PESVKNFVLRTKVVKAVRKYLDDKGFLEVETPILNTIPGGATARPFITHHNQLDIQMYMR 233 Query: 238 IAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESL 297 IAPELYLK LVVGG RV+EI R FRNEGI HNPEFT E YMAYADY+D++++TE L Sbjct: 234 IAPELYLKELVVGGINRVYEIGRLFRNEGIDQTHNPEFTTCEFYMAYADYNDIMKMTEEL 293 Query: 298 FRTLAQEVL-GTTKVTYGEHVFDFG-----------------KPFEKLTMREAIKKYRPE 339 + +++ G+TK+ + + D +PF + I+K+ E Sbjct: 294 LGNMVKDITGGSTKLEIKDRLMDINNEEDIKMLEKFFKEPIPRPFNSAECSKVIEKHCTE 353 Query: 340 TD-MADLDNFDAAK---------------------------ALAESIG------------ 359 + D +N A K AL E G Sbjct: 354 LNYYYDGNNEKAMKKLFADFVTEKKMVLDFTAPFKRISYVHALEEKFGEKIPRPLDGPEA 413 Query: 360 ITVEKSWGL------------GRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVN 407 +T K + R++ ++F ++ E L+QPTF+ + P +SPLA+ + Sbjct: 414 LTFLKKQAIRFNAICAEPQTTARVMDKLFGDLIEVDLVQPTFVCDQPQLMSPLAKYHRSE 473 Query: 408 PEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEY 467 PE+T+RFE FI REI N ++ELN+ Q F++Q KAAGDDEA DE ++ A+E+ Sbjct: 474 PELTERFELFILKREIANAYTELNNPIVQRSNFEQQAKDKAAGDDEAQLVDEVFLDAIEH 533 Query: 468 GLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQ 504 PPT G G+GIDR+ ML + I++VILFP MRP+ Sbjct: 534 AFPPTGGWGLGIDRLAMLLADVDNIKEVILFPTMRPE 570 >6AQG-A nrPDB Length = 506 Score = 346 bits (887), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 200/506 (39%), Positives = 305/506 (60%), Gaps = 29/506 (5%) Query: 14 DFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEF-DAKDNQELESLNIEVSVA 71 + ++ R RR+K A L +G +P R HT ++ + D + E + V VA Sbjct: 15 NIPEQFRIRRDKRARLLAEGYDPYPVAIERTHTLAEIRATYADLPTDSATEDI---VGVA 71 Query: 72 GRMMTRRIMGKASFVTLQDV-GGRIQLYVARDSLPEGVYNDQFKKW----DLGDIIGARG 126 GR++ R GK F TLQD G ++Q ++ D V + +W D+GD++ G Sbjct: 72 GRVVFARNTGKLCFATLQDGDGTQLQAMISLDE----VGRESLDRWKADVDIGDVVYVHG 127 Query: 127 TLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVV 186 T+ ++ GELS+ R+ KALRPLP H +E R RQRY+DLI ++R+ Sbjct: 128 TVISSRRGELSVLADSWRMAAKALRPLPVA-HKEMSEESRVRQRYVDLIVRPQAREVARQ 186 Query: 187 RSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKR 246 R ++ A+R + RGF+EVETPM+Q + GGA+ARPF+TH NALD+D+YLRIAPEL+LKR Sbjct: 187 RIAVIRAVRNALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLKR 246 Query: 247 LVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVL 306 +VGGF+RVFE+NR FRNEG H+PEF+M+E Y Y Y D +T L + +A E + Sbjct: 247 CIVGGFDRVFELNRVFRNEGSDSTHSPEFSMLETYQTYGTYDDSALITRELIQEVADEAI 306 Query: 307 GTTKVTYGE-HVFDFGKPFEKLTMREAI-----KKYRPETDMADLDNFDAAKALAESIGI 360 GT +++ + V+D + + M ++ ++ PET +A L + +A + + Sbjct: 307 GTRQLSMPDGSVYDIDGEWATMEMYSSLSEALGEQITPETTVARL------RDIASGLDV 360 Query: 361 TVEKS-WGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIG 419 ++ S +G G++V E+++ L PTF+ ++P E +PL R++ P +T++++ ++ Sbjct: 361 EIDNSVFGHGKLVEELWEHAVGNKLTAPTFVKDFPVETTPLTRQHRSIPGVTEKWDLYVR 420 Query: 420 GREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGI 479 G E+ G+SELND Q +RF +Q A AAGDDEAM DED++TALEYG+PP G G+GI Sbjct: 421 GVELATGYSELNDPVVQRDRFADQARAAAAGDDEAMQLDEDFLTALEYGMPPCTGTGMGI 480 Query: 480 DRMIMLFTNSHTIRDVILFPAMRPQK 505 DR++M T +IR+ +LFP +RP Sbjct: 481 DRLLMCLTG-LSIRETVLFPIVRPHS 505 >6NRZ-A nrPDB Length = 534 Score = 335 bits (860), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 189/456 (41%), Positives = 278/456 (60%), Gaps = 22/456 (4%) Query: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD-------SLPEGVYNDQF--KKWD 117 +V AGR++ R MGK +F + D +IQ+ RD + G+ +F KK D Sbjct: 74 KVRFAGRLVLFRSMGKNAFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIEKKLD 133 Query: 118 LGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIAN 177 LGDI+G G LF T +GEL++ + LL K+L LPDK GL D+E+RYR+R+ DLI++ Sbjct: 134 LGDILGLEGYLFFTHSGELTVLVETVTLLCKSLISLPDKHAGLADKEIRYRKRWADLISS 193 Query: 178 DKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLR 237 + R+TF+ RS+IL IR++M + F+EVETP++Q + GGA A PF+T AL +M+LR Sbjct: 194 EDVRKTFLTRSRILKLIREYMDQQSFLEVETPILQTVYGGAEATPFVTTLQALHAEMFLR 253 Query: 238 IAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESL 297 I+ E+ LK+L+VGG RV+EI + FRNEGI HNPEFTM+E Y AY DY+D+++ E+L Sbjct: 254 ISLEIALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAAYWDYNDVMKCVENL 313 Query: 298 FRTLAQEV-LGTTKVTY-----GEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAA 351 + + + G T+V Y G V DF P+ ++TM+E+I Y DL Sbjct: 314 VEYIVRALNNGETQVQYSHLKSGPQVVDFKAPWIRMTMKESISVYGGVD--VDLHADHEL 371 Query: 352 KALAESIGITVEKSW---GLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNP 408 + + E+ EK++ G ++ +FDE+ LI P IT++P E +PL + Sbjct: 372 RKILETQTSLPEKTYVHASRGELIALLFDELVCDKLIAPHHITDHPLETTPLCKTLRSGD 431 Query: 409 E-ITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG-DDEAMFYDEDYVTALE 466 E + +RFE F G+E+ N +SELND Q + +EQ+ KA D E DE+++ AL Sbjct: 432 ETLVERFESFCLGKELCNAYSELNDPLQQRKLLEEQMRKKALNPDSEYHPIDEEFLEALC 491 Query: 467 YGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 G+PP G GIGIDR++M+ T++ +IRDV+ FP MR Sbjct: 492 QGMPPAGGFGIGIDRLVMMLTDAASIRDVLFFPVMR 527 >6AQH-A nrPDB Length = 508 Score = 333 bits (855), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 197/501 (39%), Positives = 300/501 (59%), Gaps = 20/501 (3%) Query: 14 DFNDELRNRREKLAALRQQG-VAFPNDFRRDHTSDQLHEEF-----DAKDNQELESLNIE 67 D ++ R R+ K A L QG +P D R HT ++ + + DA+ + Sbjct: 18 DLPEQFRIRQAKRADLLAQGRQPYPVDVPRTHTLLEIRQAYPDLPVDARTGEI------- 70 Query: 68 VSVAGRMMTRRIMGKASFVTLQDV-GGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARG 126 V V GR++ R GK F TLQ+ G ++Q ++ + + ++ D+GDI+ G Sbjct: 71 VGVTGRVVFARNSGKLCFATLQEGDGTQLQAMISLAEVGQEALDNWKTYVDIGDIVFVHG 130 Query: 127 TLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVV 186 + ++ GELS+ ++ KALRPLP H +E R RQRY+DLI D++R+ Sbjct: 131 EVITSKRGELSVLADSWQMAAKALRPLPVA-HKEMSEESRVRQRYVDLIVRDQARKVARQ 189 Query: 187 RSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKR 246 R ++ AIR + RGF+EVETPM+Q + GGA+ARPF+TH NALD ++YLRIAPEL+LKR Sbjct: 190 RIAVMRAIRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDTELYLRIAPELFLKR 249 Query: 247 LVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVL 306 +VGGFERVFE+NR FRNEG H+PEF M+E Y AY Y D +T L + +A E + Sbjct: 250 CLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQAYGTYDDSAVVTRELIQEVADEAI 309 Query: 307 GTTKVTYGE-HVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITV--E 363 GT +V + V+D +E + M ++ + E D + A+A+ +G+ + + Sbjct: 310 GTRQVPLPDGTVYDLDGEWESIQMYPSLSEALGEEITPDTPA-ETLWAIADRLGLDIPRD 368 Query: 364 KSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREI 423 + +G G++V E+++ A L PTF+ ++P E +PL R + P +T++++ ++ E+ Sbjct: 369 RGYGHGKLVEELWEHTVGAKLWAPTFVKDFPVETTPLTRSHRSIPGVTEKWDLYVRRIEL 428 Query: 424 GNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMI 483 G+SEL D Q ERF+ Q A AAGDDEAM DED++ ALEYG+PP+ G G+GIDR++ Sbjct: 429 ATGYSELTDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGMPPSTGTGMGIDRLM 488 Query: 484 MLFTNSHTIRDVILFPAMRPQ 504 M T +IR+ +LFP ++P+ Sbjct: 489 MTLTG-LSIRETVLFPIVKPR 508 >3G1Z-A nrPDB Length = 326 Score = 154 bits (390), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 106/323 (32%), Positives = 168/323 (52%), Gaps = 32/323 (9%) Query: 187 RSKILAAIRQFMVARGFMEVETPMM-QVIPGGASARPFITHH----NALDLDMYLRIAPE 241 R+ I+A IR+F RG +EVETP M Q PF T ++ +++YL +PE Sbjct: 20 RAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGINLYLMTSPE 79 Query: 242 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 301 ++KRL+ G VF++ R+FRNE + HNPEFTM+E Y + D + L+ + L Sbjct: 80 YHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLL--- 136 Query: 302 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFD----AAKALAES 357 Q+VL +P E L+ ++A +++ E D D AAK + Sbjct: 137 -QQVLDC-------------QPAESLSYQQAFQRHL-EIDPLSADKTQLREAAAKLDLSN 181 Query: 358 IGITVEKSWGLGRIVTEIFDEVAEAHL--IQPTFITEYPAEVSPLARRNDVNPEITDRFE 415 I T E L ++ +F E H+ +PTFI +PA + LA+ + + + +RFE Sbjct: 182 IADTEEDRDTLLQL---LFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDHRVAERFE 238 Query: 416 FFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGL 475 + G E+ NGF EL DA +Q +RF++ +AA D++ + AL GLP +G+ Sbjct: 239 VYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQQPIDQNLLDALAAGLPDCSGV 298 Query: 476 GIGIDRMIMLFTNSHTIRDVILF 498 +G+DR++ML + ++ DVI F Sbjct: 299 ALGVDRLVMLALGAESLADVIAF 321 >3A5Z-A nrPDB Length = 328 Score = 147 bits (371), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 103/327 (31%), Positives = 168/327 (51%), Gaps = 32/327 (9%) Query: 187 RSKILAAIRQFMVARGFMEVETPMM-QVIPGGASARPFITHH----NALDLDMYLRIAPE 241 R+ I+A IR+F RG +EVETP M Q PF T ++ ++++L +PE Sbjct: 22 RAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPE 81 Query: 242 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 301 ++KRL+V G VF++ R+FRNE + HNPEFTM+E Y + D + L+ + L Sbjct: 82 YHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLL--- 138 Query: 302 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFD----AAKALAES 357 Q+VL E L+ ++A +Y E D D AAK + Sbjct: 139 -QQVLDCPAA-------------ESLSYQQAFLRYL-EIDPLSADKTQLREVAAKLDLSN 183 Query: 358 IGITVEKSWGLGRIVTEIFDEVAEAHL--IQPTFITEYPAEVSPLARRNDVNPEITDRFE 415 + T E L ++ +F E ++ +PTF+ +PA + LA+ + + + +RFE Sbjct: 184 VADTEEDRDTLLQL---LFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFE 240 Query: 416 FFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGL 475 + G E+ NGF EL DA +Q +RF++ +AA D++ + AL+ G+P +G+ Sbjct: 241 VYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGV 300 Query: 476 GIGIDRMIMLFTNSHTIRDVILFPAMR 502 +G+DR++ML + T+ +VI F R Sbjct: 301 ALGVDRLVMLALGAETLAEVIAFSVDR 327 >1WYD-A nrPDB Length = 429 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 116/466 (24%), Positives = 210/466 (45%), Gaps = 55/466 (11%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H + E+D K EV AG + R +G F+ L+D G Q+ V + Sbjct: 3 RSHFIADVTPEYDGK----------EVIWAGWVHLLRDLGGKKFIILRDKTGLGQVVVDK 52 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGE--LSIHCTELRLLTKALRPLPDKFHG 159 +S G+ + ++ +I RG + + + +H E+ LL+KA PLP G Sbjct: 53 NSSAFGISQELTQE----SVIQVRGIVKADKRAPRGIELHAEEITLLSKAKAPLPLDVSG 108 Query: 160 L--QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETP--MMQVIP 215 D + R R+R LDL + + ++S L A R+ + GF+E+ TP + Sbjct: 109 KVKADIDTRLRERVLDL-RRQEMQAVIKIQSLALKAFRETLYKEGFIEIFTPKIIASATE 167 Query: 216 GGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 274 GGA P I + +L +P+LY K L+ G ERVFE+ +R E + H E Sbjct: 168 GGAQLFPVIYFGK----EAFLAQSPQLY-KELMAGVVERVFEVAPAWRAEESDTPFHLAE 222 Query: 275 FTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK 334 F M++ MA+ADY+D+++L E + + + + K + ++ P K+ ++ Sbjct: 223 FISMDVEMAFADYNDVMQLLEKILHNIVKTIKEEGKEEL--KILNYEPPEVKIPIKRL-- 278 Query: 335 KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYP 394 + A + S G ++ +G I +E + L FI ++P Sbjct: 279 ------------KYTEAIEILRSKGYNIKFGDDIGTPELRILNEELKEDL---YFIVDWP 323 Query: 395 AEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDE 453 ++ P + NPE+++ F+ EI +G + + E +E + K + Sbjct: 324 SDARPFYTKSKSENPELSESFDLIYKFLEIVSG----STRNHKREVLEEALKKKGLKPES 379 Query: 454 AMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 F+ + +YG+PP AG G+G+ R++++ T ++++++ FP Sbjct: 380 FEFF----LKWFDYGMPPHAGFGMGLARLMVMLTGIQSVKEIVPFP 421 >1ASZ-A nrPDB Length = 490 Score = 116 bits (290), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 120/484 (24%), Positives = 207/484 (42%), Gaps = 73/484 (15%) Query: 57 DNQELESLNIEVSVAGRMMTRRIMGKA-SFVTLQDVGGRIQLYVARDSLPEGVYNDQFKK 115 D E + + EV R+ R G +F+TL+ IQ V + EG + K Sbjct: 31 DLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANK--EGTISKNMVK 88 Query: 116 W----DLGDIIGARGTLFKTQ-------TGELSIHCTELRLLTKALRPLP---------- 154 W +L I+ RG + K L IH T++ +++ LP Sbjct: 89 WAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSE 148 Query: 155 --DKFHGLQ----DQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVET 208 + GL D + YR L + N + F +++ + R+++ + F EV T Sbjct: 149 AEAEAAGLPVVNLDTRLDYRVIDLRTVTN---QAIFRIQAGVCELFREYLATKKFTEVHT 205 Query: 209 PMMQVIPGGASARPF-ITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGI 267 P + P + F +T+ YL +P+ ++L+V FERV+EI FR E Sbjct: 206 PKLLGAPSEGGSSVFEVTYFKG---KAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENS 262 Query: 268 SV-RHNPEFTMMELYMAYAD-YHDLIELTESLFRTLAQEV-------LGTTKVTYGEHVF 318 + RH EFT +++ MA+ + YH++++ LF + E+ + + Y F Sbjct: 263 NTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEF 322 Query: 319 DFGK--PFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIF 376 K +LT +E I+ R A K + + ++ E LG++V + + Sbjct: 323 KLPKDGKMVRLTYKEGIEMLRA-----------AGKEIGDFEDLSTENEKFLGKLVRDKY 371 Query: 377 DEVAEAHLIQPTFITEYPAEVSPLARRND-VNPEITDRFEFFIGGREIGNGFSELNDAED 435 D + ++P E+ P D NP+ ++ ++FF+ G EI +G ++D Sbjct: 372 D-------TDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHA- 423 Query: 436 QAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDV 495 QE++ A ++ +DY YG PP AG GIG++R++M + + IR Sbjct: 424 ---LLQERMKAHGLSPEDPGL--KDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRA 478 Query: 496 ILFP 499 LFP Sbjct: 479 SLFP 482 >3I7F-A nrPDB Length = 548 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 102/376 (27%), Positives = 177/376 (47%), Gaps = 54/376 (14%) Query: 146 LTKALRPLPDKFHGL------------QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAA 193 LTK RPL D++ L Q+ R R LDL + F ++S Sbjct: 197 LTK--RPLKDEYAKLLKEKASAQKYVKVSQDTRLDNRMLDL-RTVTNIAIFRIQSACCGL 253 Query: 194 IRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFE 253 R+F+ ++ F+E+ TP ++I + I D YL +P+LY + ++G F Sbjct: 254 FREFLTSQKFVEIHTP--KLIGCSSEGGSNIFEVKYFDRKAYLAQSPQLYKQMAIMGDFR 311 Query: 254 RVFEINRNFRNEGISVR-HNPEFTMMELYMAYA-DYHDLIELTESLFRTLAQEVLG---- 307 +VFE+ FR E + R H EF +++ M +YH+ I++ E LF + E+ Sbjct: 312 KVFEVGPVFRAENSNTRRHLTEFEGLDIEMEIVENYHECIDVMEKLFTFIFDEIPKRFPD 371 Query: 308 TTKVTYGEHVFD--FGKPFEKLTMREAIKKYRPETD-MADLDNFDAAKALAESIGITVEK 364 KV ++ F+ +PF +LT +EAI+ R + + D D+F T + Sbjct: 372 ELKVIRKQYPFEDLIYRPFLRLTYKEAIEMLRASGETIGDYDDF------------TTPQ 419 Query: 365 SWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVN-PEITDRFEFFIGGREI 423 LG ++ ++ + +++ ++PA + P D++ P ++ ++ F+ G+EI Sbjct: 420 EVKLGELIKAKYN--TDFYILD-----KFPAAIRPFYTMPDIDDPNYSNSYDVFVRGQEI 472 Query: 424 GNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMI 483 +G ++D E +R E+ G D A +DY+ + +G P AG GIG++R+ Sbjct: 473 TSGAQRIHDPEFLMKRCIEK------GVDPATL--KDYIESFRFGSWPHAGCGIGLERIT 524 Query: 484 MLFTNSHTIRDVILFP 499 ML+ IR V LFP Sbjct: 525 MLYLGIPNIRKVTLFP 540 >3NEM-A nrPDB Length = 438 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 121/475 (25%), Positives = 205/475 (43%), Gaps = 58/475 (12%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H S ++ EE + + +V VAG + + +G F+ ++D G +Q+ + Sbjct: 3 RTHYSSEITEELNGQ----------KVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPK 52 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELS--IHCTELRLLTKALRPLPDKFHG 159 + ++ K D++ G + T +L I ++ +L +A PLP G Sbjct: 53 KKVDPELFK-LIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTG 111 Query: 160 LQDQEV--RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETP--MMQVIP 215 E+ R R++DL + F +RS + A+R F GF+E+ TP + Sbjct: 112 KVKAELDTRLDNRFMDL-RRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATE 170 Query: 216 GGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPE 274 GG P + D +L +P+LY + ++ G +RV+EI FR E + RH E Sbjct: 171 GGTELFPM----KYFEEDAFLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRHLNE 226 Query: 275 FTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGE-HVFDF-----GKPFEKLT 328 ++ MA+ + D E+ L R +A + + E + +F PF +++ Sbjct: 227 AWSIDSEMAFIE--DEEEVMSFLERLVAHAINYVREHNAKELDILNFELEEPKLPFPRVS 284 Query: 329 MREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPT 388 +A++ + DL K + I E LG+ + E +E A + Sbjct: 285 YDKALEI------LGDL-----GKEIPWGEDIDTEGERLLGKYMME--NENAPLY----- 326 Query: 389 FITEYPAEVSPL-ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAK 447 F+ +YP+E P + D PEI F+ G EI +G E + + EQ+ K Sbjct: 327 FLYQYPSEAKPFYIMKYDNKPEICRAFDLEYRGVEISSG----GQREHRHDILVEQIKEK 382 Query: 448 AAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 + F Y+ A YG+PP G G+G +R+I + IR+VILFP R Sbjct: 383 GLNPESFEF----YLKAFRYGMPPHGGFGLGAERLIKQMLDLPNIREVILFPRDR 433 >1N9W-A nrPDB Length = 422 Score = 105 bits (263), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 115/449 (25%), Positives = 197/449 (43%), Gaps = 65/449 (14%) Query: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVA--RDSLPEGVYNDQFKKWDLGDIIGA 124 EV + G + RR +G+ F+ L+D G +Q+ + LPE + Sbjct: 15 EVELLGFLHWRRDLGRIQFLLLRDRSGVVQVVTGGLKLPLPESA-------------LRV 61 Query: 125 RGTLFKTQT--GELSIHCTELRLLTKALRPLP-----DKFHGLQDQEVRYRQRYLDLIAN 177 RG + + G L + E+ +L+ AL P P +++ D + YR Y+ L Sbjct: 62 RGLVVENAKAPGGLEVQAKEVEVLSPALEPTPVEIPKEEWRANPDTLLEYR--YVTL-RG 118 Query: 178 DKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLR 237 +K+R V++ ++ R+++ + F E+ TP +V+ GA + + + YL Sbjct: 119 EKARAPLKVQAALVRGFRRYLDRQDFTEIFTP--KVVRAGAEGGSGLFGVDYFEKRAYLA 176 Query: 238 IAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPEFTMMELYMAY-ADYHDLIELTE 295 +P+LY K+++VG FERV+E+ +R E + RH E+ +++ M + AD DL+ L E Sbjct: 177 QSPQLY-KQIMVGVFERVYEVAPVWRMEEHHTSRHLNEYLSLDVEMGFIADEEDLMRLEE 235 Query: 296 SLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALA 355 +L + +E L T G+ + G + D+ L + +A + L Sbjct: 236 ALLAEMLEEALNTA----GDEIRLLGATWPSFPQ-----------DIPRLTHAEAKRILK 280 Query: 356 ESIGITVEK--SWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPE---I 410 E +G V + S R++ E E + + F+T YP V P PE Sbjct: 281 EELGYPVGQDLSEEAERLLGEYAKERWGSDWL---FVTRYPRSVRPFY----TYPEEDGT 333 Query: 411 TDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLP 470 T F+ G EI +G ++ E+ E + KA G D F+ Y+ +YG+P Sbjct: 334 TRSFDLLFRGLEITSGGQRIHRYEELLE------SLKAKGMDPEAFHG--YLEVFKYGMP 385 Query: 471 PTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 P G IG +R+ +R FP Sbjct: 386 PHGGFAIGAERLTQKLLGLPNVRYARAFP 414 >4J15-A nrPDB Length = 521 Score = 105 bits (261), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 93/349 (26%), Positives = 156/349 (44%), Gaps = 41/349 (11%) Query: 162 DQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASAR 221 +Q+ R R +DL S+ F ++S I R+ ++ +GF+E++TP + A Sbjct: 195 NQDTRLDNRVIDL-RTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGAN 253 Query: 222 PFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV-RHNPEFTMMEL 280 F + + YL +P+LY + + FE+VF I FR E + RH EF +++ Sbjct: 254 VFTVSY--FKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDI 311 Query: 281 YMAYA-DYHDLIE----LTESLFRTLA---QEVLGTTKVTYGEHVFDFGKPFEKLTMREA 332 MA+ YH+++E +F+ L Q + T + F F +P +L EA Sbjct: 312 EMAFNYHYHEVMEEIADTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEA 371 Query: 333 IKKYRPE-TDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFIT 391 + R +M D D+ ++ LG +V E +D + Sbjct: 372 LAMLREAGVEMGDEDD------------LSTPNEKLLGHLVKEKYD-------TDFYILD 412 Query: 392 EYPAEVSPLARRNDV-NPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG 450 +YP V P D NP+ ++ ++ F+ G EI +G ++D + ER A G Sbjct: 413 KYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTER------ALHHG 466 Query: 451 DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 D + Y+ + +G PP AG GIG++R+ MLF H +R +FP Sbjct: 467 IDLEKI--KAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFP 513 >4WJ3-M nrPDB Length = 599 Score = 94.0 bits (232), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 86/319 (26%), Positives = 151/319 (47%), Gaps = 47/319 (14%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H QL+E D + EV++ G + RR G F+ ++D G Q+ Sbjct: 11 RSHYCGQLNESLDGQ----------EVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDP 60 Query: 102 DSLPEGVYNDQFKKWDLGDIIG--------ARGTLFKTQTGELSIHCTELRLLTKA-LRP 152 D D+ + + I G AR +G + + EL +L +A P Sbjct: 61 DRAETFAKADRVRSEFVVKITGKVRLRPEGARNP--NMASGSIEVLGYELEVLNQAETPP 118 Query: 153 LPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM- 211 P + +E R R R++DL + + + +R++I ++IR+++ GF++VETP++ Sbjct: 119 FPLDEYSDVGEETRLRYRFIDLRRPEMAAK-LKLRARITSSIRRYLDDNGFLDVETPILG 177 Query: 212 QVIPGGA-----SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEG 266 + P GA +R + H AL +P+L+ + L+V GF+R ++I + FR+E Sbjct: 178 RPTPEGARDYLVPSRTYPGHFFALPQ------SPQLFKQLLMVAGFDRYYQIAKCFRDED 231 Query: 267 ISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEK 326 + PEFT +++ ++ D D+I +TE + R L +EVL V + E F Sbjct: 232 LRADRQPEFTQIDIETSFLDESDIIGITEKMVRQLFKEVL---DVEFDE--------FPH 280 Query: 327 LTMREAIKKYRPETDMADL 345 + EA+++Y +D DL Sbjct: 281 MPFEEAMRRY--GSDKPDL 297 Score = 55.1 bits (131), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 12/100 (12%) Query: 405 DVNP--EITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDY- 461 + NP ++ ++ + G E+G G ++D Q F + G DEA +E + Sbjct: 472 EANPGAALSRAYDMVLNGTELGGGSIRIHDKSMQQAVF------RVLGIDEAE-QEEKFG 524 Query: 462 --VTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 + AL+YG PP GL G+DR++ML T + +IR+VI FP Sbjct: 525 FLLDALKYGAPPHGGLAFGLDRLVMLMTGASSIREVIAFP 564 >4RMF-A nrPDB Length = 609 Score = 92.0 bits (227), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 81/302 (26%), Positives = 136/302 (45%), Gaps = 59/302 (19%) Query: 68 VSVAGRMMTRRIMGKASFVTLQDVGG------------------RIQLYVARDSL----P 105 V++AG + RR G F+ L+D G R + VA + P Sbjct: 19 VTLAGWVARRRDHGGVIFIDLRDASGVSQVVFREGDVLAAAHRLRAEFCVAVTGVVEVRP 78 Query: 106 EGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEV 165 EG N + TG++ ++ TEL +L ++ PLP + +E Sbjct: 79 EGNENPEIP------------------TGQIEVNATELTVLGESA-PLPFQLDEQAGEEA 119 Query: 166 RYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM-QVIPGGASARPFI 224 R + RYLDL + +RSK+ AA R + F+E+ETP + + P GA R F+ Sbjct: 120 RLKYRYLDL-RREGPGNALRLRSKVNAAARSVLAEHDFVEIETPTLTRSTPEGA--RDFL 176 Query: 225 THHNALDLDMY-LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMA 283 Y L +P+L+ + L+V G ER ++I R +R+E PEFT +++ M+ Sbjct: 177 VPARLQPGSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDMEMS 236 Query: 284 YADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMA 343 + + D+I ++E +VL T G +D P +++ EA++++ +D Sbjct: 237 FVEADDVIAISE--------QVLKAVWATIG---YDLPLPLPRISYEEAMRRF--GSDKP 283 Query: 344 DL 345 DL Sbjct: 284 DL 285 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 6/97 (6%) Query: 404 NDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGD-DEAMFYDEDYV 462 +D ++D ++ G EIG G ++ + QE+V A D DEA + Sbjct: 464 SDPGNALSDAYDIVCNGNEIGGGSIRIHRRD-----IQERVFAMMGIDHDEAQEKFGFLL 518 Query: 463 TALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 A YG PP G+ G DR+ L +IR+VI FP Sbjct: 519 DAFSYGAPPHGGIAFGWDRITALLAGVDSIREVIAFP 555 >6OD8-A nrPDB Length = 558 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 116/494 (23%), Positives = 209/494 (42%), Gaps = 82/494 (16%) Query: 62 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI 121 E ++ V + R+ T R GK +F+ L+D +Q A + D + I Sbjct: 83 ELVDKTVLIRARVSTTRKKGKMAFMVLRDGSDSVQAMAAVEGDVPKEMIDFMGQIATESI 142 Query: 122 IGARGTLFK-------TQTGELSIHCTELRLLTKALRPLPDKFHGLQDQE---------- 164 + T+ K T ++ + ++ +T++LR LP +E Sbjct: 143 VDVEATVCKVEQPITSTSHSDIELKVKKIHTVTESLRTLPFTLEDASRKESAEGAKVNLD 202 Query: 165 VRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFI 224 R R++DL S F ++S++ RQF++ + F E+ +P + P A F Sbjct: 203 TRLNSRWMDL-RTLASGAIFRLQSRVCQYFRQFLIDKDFCEIHSPKIINAPSEGGANVFK 261 Query: 225 THHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV-RHNPEFTMMELYMA 283 + + YL +P+LY + ++ G RVFE+ FR+E + RH EF +++ M Sbjct: 262 LEY--FNRFAYLAQSPQLYKQMVLQGDVPRVFEVGPVFRSENSNTHRHLTEFVGLDVEMR 319 Query: 284 YAD-YHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMR---EAIKKY--- 336 + Y++++++ ESLF + + + TK ++V PFE L + E IK+ Sbjct: 320 IDEHYYEVLDVAESLFNYIFERLATHTKEL--KNVCQ-QYPFEPLVWKLTPERIKELGVG 376 Query: 337 ----------RPETDMADLDN-----------------FDAAKALAESIGITVEKSWGLG 369 + + + ++D+ D A + I T EK LG Sbjct: 377 VISEGVVPTDKFQARVHNMDSRMLRINYMHCIELLNTVLDEKMAPTDDINTTNEKL--LG 434 Query: 370 RIVTEIFDEVAEAHLIQPTFITE-YPAEVSP---LARRNDVNPEITDRFEFFIGGREIGN 425 ++V E + FI++ +P+ P + ++DV T+ ++ FI G EI + Sbjct: 435 KLVKERYG--------TDFFISDRFPSSARPFYTMECKDDVR--FTNSYDMFIRGEEISS 484 Query: 426 GFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIML 485 G ++D + R AK D ++YV + G P G GIG++R++ML Sbjct: 485 GAQRIHDPDLLLAR------AKMLNVDLTPI--KEYVDSFRLGAWPHGGFGIGLERVVML 536 Query: 486 FTNSHTIRDVILFP 499 + +R LFP Sbjct: 537 YLGLSNVRLASLFP 550 >1IL2-A nrPDB Length = 590 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 80/303 (26%), Positives = 145/303 (47%), Gaps = 33/303 (10%) Query: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGD 120 L + +V++ G + RR +G F+ ++D G +Q++ D + + Sbjct: 11 LSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQ 70 Query: 121 IIGA------RGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDL 174 + G + TGE+ + + L ++ +A LP + + +E R + RYLDL Sbjct: 71 VTGTVRARDEKNINRDMATGEIEVLASSLTIINRA-DVLPLDSNHVNTEEARLKYRYLDL 129 Query: 175 IANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM-QVIPGGASARPFITHHNALDLD 233 + + Q R+KI + +R+FM GF+++ETPM+ + P GA R ++ Sbjct: 130 RRPEMA-QRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGA--RDYLVPSRVHKGK 186 Query: 234 MY-LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIE 292 Y L +P+L+ + L++ GF+R ++I + FR+E + PEFT +++ ++ + E Sbjct: 187 FYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVRE 246 Query: 293 LTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKY---RPE-------TDM 342 + E+L R L EV G D G F +T EA ++Y +P+ TD+ Sbjct: 247 VMEALVRHLWLEVKGV----------DLGD-FPVMTFAEAERRYGSDKPDLRNPMELTDV 295 Query: 343 ADL 345 ADL Sbjct: 296 ADL 298 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 7/148 (4%) Query: 354 LAESIGITVEKSWG-LGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITD 412 + + +G+T E W L I +F++ E L P +++ + + + Sbjct: 413 VGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVAN 472 Query: 413 RFEFFIGGREIGNGFSELNDAEDQAERFQ-EQVNAKAAGDDEAMFYDEDYVTALEYGLPP 471 ++ I G E+G G +++ + Q F +N + + D AL+YG PP Sbjct: 473 AYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLD-----ALKYGTPP 527 Query: 472 TAGLGIGIDRMIMLFTNSHTIRDVILFP 499 AGL G+DR+ ML T + IRDVI FP Sbjct: 528 HAGLAFGLDRLTMLLTGTDNIRDVIAFP 555 >5W25-A nrPDB Length = 616 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 82/290 (28%), Positives = 137/290 (47%), Gaps = 30/290 (10%) Query: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARG 126 +V++AG + RR G F+ L+D G Q+ V RD V Q + + G Sbjct: 40 QVTLAGWVARRRDHGGVIFIDLRDASGIAQV-VFRDPQDTEVLA-QAHRLRAEFCVSVAG 97 Query: 127 TL---------FKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIAN 177 + + TGE+ ++ T L +L + PLP + +E+R + RYLDL + Sbjct: 98 VVEIRPEGNANPEIATGEIEVNATSLTVLGECA-PLPFQLDEPAGEELRLKYRYLDLRRD 156 Query: 178 DKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM-QVIPGGASARPFITHHNALDLDMY- 235 D + +RS++ AA R + F+E+ETP + + P GA R F+ Y Sbjct: 157 DPA-AAIRLRSRVNAAARAVLARHDFVEIETPTITRSTPEGA--RDFLVPARLHPGSFYA 213 Query: 236 LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTE 295 L +P+L+ + L+V G ER ++I R +R+E PEFT +++ M++ D D+I ++E Sbjct: 214 LPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDMEMSFVDAEDIIAISE 273 Query: 296 SLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADL 345 EVL G + P ++ EA++++ TD DL Sbjct: 274 --------EVLTELWALIG---YRIPTPIPRIGYAEAMRRF--GTDKPDL 310 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 4/96 (4%) Query: 404 NDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVT 463 +D + D ++ G EIG G ++ + Q F KA +++ F E ++ Sbjct: 489 SDTGSVLADAYDIVCNGHEIGGGSVRIHRRDIQERVFAVMGLDKAEAEEKFGFLLEAFM- 547 Query: 464 ALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 +G PP G+ G DR L +IR+VI FP Sbjct: 548 ---FGAPPHGGIAFGWDRTTALLAGMDSIREVIAFP 580 >1X54-A nrPDB Length = 434 Score = 85.1 bits (209), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 107/454 (23%), Positives = 191/454 (42%), Gaps = 66/454 (14%) Query: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARG 126 +V +AG + T +GK F+ ++D G +Q VA++ + E + ++ KK + G Sbjct: 18 KVRLAGWVYTNMRVGKKIFLWIRDSTGIVQAVVAKNVVGEETF-EKAKKLGRESSVIVEG 76 Query: 127 TLFKTQ--TGELSIHCTELRLLTKALR-PLPDKFHGLQDQEVRYRQRYLDLIANDKSRQT 183 + + G +H +L ++ P+P+ E+ R+L I K+ Sbjct: 77 IVKADERAPGGAEVHVEKLEVIQAVSEFPIPENPEQ-ASPELLLDYRHLH-IRTPKASAI 134 Query: 184 FVVRSKILAAIRQFMVARGFMEVETPMM--QVIPGGASARPFITHHNALDLDMYLRIAPE 241 V+ ++ A R++++ G+ EV P++ + GGA+ + D YL + + Sbjct: 135 MKVKETLIMAAREWLLKDGWHEVFPPILVTGAVEGGAT----LFKLKYFDKYAYLSQSAQ 190 Query: 242 LYLKRLVVGGFERVFEINRNFRNEGISVR-HNPEFTMMELYMAYADYHDLIELTESLFRT 300 LYL+ + G E+V+ + +FR E R H EF +EL A+ D D++++ E L Sbjct: 191 LYLEAAIFG-LEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSY 249 Query: 301 LAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDN---------FDAA 351 + Q L K + I+ +R D+ L N +D A Sbjct: 250 MVQRTLELRK--------------------KEIEMFR--DDLTTLKNTEPPFPRISYDEA 287 Query: 352 KALAESIGITVEKSWG--LG----RIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRND 405 + +S G+ VE WG LG R++TE FD +P F+ YP + + D Sbjct: 288 IDILQSKGVNVE--WGDDLGADEERVLTEEFD--------RPFFVYGYPKHIKAFYMKED 337 Query: 406 VNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTAL 465 N D + G+ E+ + + + + +N + Y E Y+ Sbjct: 338 PN----DPRKVLASDMLAPEGYGEIIGGSQREDDYDKLLNRILEEGMDPKDY-EWYLDLR 392 Query: 466 EYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 YG P +G G+G++R++ IR LFP Sbjct: 393 RYGSVPHSGFGLGVERLVAWVLKLDHIRWAALFP 426 >1EFW-A nrPDB Length = 580 Score = 85.1 bits (209), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 84/321 (26%), Positives = 152/321 (47%), Gaps = 45/321 (14%) Query: 41 RRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVA 100 RR H + L E + EV + G + RR +G F+ L+D G +QL VA Sbjct: 2 RRTHYAGSLRET----------HVGEEVVLEGWVNRRRDLGGLIFLDLRDREGLVQL-VA 50 Query: 101 RDSLPEGVYNDQFK-KWDLGDIIGARGTLF-------KTQTGELSIHCTELRLLTKALRP 152 + P ++ + +W ++ A+G + + TG + + + L +L +A P Sbjct: 51 HPASPAYATAERVRPEW----VVRAKGLVRLRPEPNPRLATGRVEVELSALEVLAEAKTP 106 Query: 153 LPDKFHGLQDQEVRYRQRYLDL------IANDKSRQTFVVRSKILAAIRQFMVARGFMEV 206 G + +E + L L + + ++ +R +++ AI F+ GF++V Sbjct: 107 PFPVDAGWRGEEEKEASEELRLKYRYLDLRRRRMQENLRLRHRVIKAIWDFLDREGFVQV 166 Query: 207 ETPMM-QVIPGGASARPF-ITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRN 264 ETP + + P GA R F + + + L L +P+L+ + L+V G +R F+I R FR+ Sbjct: 167 ETPFLTKSTPEGA--RDFLVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRD 224 Query: 265 EGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPF 324 E + P+FT ++L M++ + D++EL E L + +E LG + PF Sbjct: 225 EDLRADRQPDFTQLDLEMSFVEVEDVLELNERLMAHVFREALGV----------ELPLPF 274 Query: 325 EKLTMREAIKKYRPETDMADL 345 +L+ EA+++Y +D DL Sbjct: 275 PRLSYEEAMERY--GSDKPDL 293 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 414 FEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTA 473 ++ + G E+G G ++D QA F+ G++E ++ ALEYG PP Sbjct: 468 YDLVLNGVEVGGGSIRIHDPRLQARVFR----LLGIGEEEQREKFGFFLEALEYGAPPHG 523 Query: 474 GLGIGIDRMIMLFTNSHTIRDVILFP 499 G+ G+DR++ L T S +IR+VI FP Sbjct: 524 GIAWGLDRLLALMTGSPSIREVIAFP 549 >4AH6-A nrPDB Length = 617 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 65/249 (26%), Positives = 123/249 (49%), Gaps = 21/249 (8%) Query: 64 LNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIG 123 L EV++ G + RR + +F+ L+D G +Q+ + +D V + + ++ Sbjct: 23 LGQEVTLCGWIQYRR---QNTFLVLRDFDGLVQVIIPQDESAASV-KKILCEAPVESVVQ 78 Query: 124 ARGTLF---------KTQTGELSIHCTELRLLTKALRPLPDKFHGL--QDQEVRYRQRYL 172 GT+ K TGE+ I LL A + LP + + + +R + RYL Sbjct: 79 VSGTVISRPAGQENPKMPTGEIEIKVKTAELLN-ACKKLPFEIKNFVKKTEALRLQYRYL 137 Query: 173 DLIANDKSRQTFVVRSKILAAIRQFMV-ARGFMEVETP-MMQVIPGGASARPFITHHNAL 230 DL + + + +RS+++ +R+++ GF+++ETP + + PGGA + F+ Sbjct: 138 DL-RSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFKRTPGGA--KEFLVPSREP 194 Query: 231 DLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDL 290 L +P+ + + L+VGG +R F++ R +R+EG PEFT +++ M++ D + Sbjct: 195 GKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQPEFTQIDIEMSFVDQTGI 254 Query: 291 IELTESLFR 299 L E L + Sbjct: 255 QSLIEGLLQ 263 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 32/89 (35%), Positives = 48/89 (53%), Gaps = 7/89 (7%) Query: 411 TDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLP 470 + ++ + G EIG G +++AE Q + A +D M + AL+YG P Sbjct: 485 SQHYDLVLNGNEIGGGSIRIHNAE-----LQRYILATLLKEDVKML--SHLLQALDYGAP 537 Query: 471 PTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 P G+ +G+DR+I L T S +IRDVI FP Sbjct: 538 PHGGIALGLDRLICLVTGSPSIRDVIAFP 566 >3M4P-A nrPDB Length = 456 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 74/333 (22%), Positives = 144/333 (43%), Gaps = 37/333 (11%) Query: 174 LIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETP-MMQVIPGGASARPFITHHNALDL 232 +I ++ ++Q +RS+I R++ F E++ P +++ G S + + N Sbjct: 146 VIRSEHTQQVLQLRSEIQWYFRKYYHDNHFTEIQPPTIVKTQCEGGSTLFKLQYFNE--- 202 Query: 233 DMYLRIAPELYLKRLVVGGFERVFEINRNFRNE-GISVRHNPEFTMMELYMAYADYHDLI 291 YL + +LYL+ V+ + F + ++R E +VRH E+ +E + + + DL+ Sbjct: 203 PAYLTQSSQLYLES-VIASLGKSFCMLSSYRAEQSRTVRHLAEYLHLEAELPFISFEDLL 261 Query: 292 ELTESLFRTLAQEVL---GTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNF 348 E L T+ V+ G H+ +PF+++T +AIK + + N Sbjct: 262 NHLEDLVCTVIDNVMAVHGDKIRKMNPHLKLPTRPFKRMTYADAIKY----CNDHGILNK 317 Query: 349 DAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPL-ARRNDVN 407 D E I E+ ++ DE+ P F+ +P+++ + + Sbjct: 318 DKPFEYGEDISEKPER---------QMTDEIG-----CPIFMIHFPSKMKAFYMSKVPGH 363 Query: 408 PEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNA-KAAGDDEAMFYDEDYVTALE 466 P++T+ + + G E+ + + E + A KA G + +Y Y + Sbjct: 364 PDLTESVDLLM------PGVGEIVGGSMRIWNYDELMGAYKANGLNPDPYYW--YTQQRK 415 Query: 467 YGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 YG P G G+G++R++M IR V L+P Sbjct: 416 YGSCPHGGYGLGVERLVMWLLGEDHIRKVCLYP 448 >5ZG8-A nrPDB Length = 438 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 107/455 (23%), Positives = 184/455 (40%), Gaps = 57/455 (12%) Query: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDLGDIIGA 124 EV + G + RR GK F+ L+D G +Q V + +PE V+ D + + G Sbjct: 15 EVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQETALRVWG- 73 Query: 125 RGTLFKTQTGELSIHCTELRLLTKAL--RPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQ 182 R + G + +L+++++ P+ K HG+ D + +R +L + R+ Sbjct: 74 RVREDRRAPGGFELAVRDLQVVSRPQGEYPIGPKEHGI-DFLMDHRHLWL------RHRR 126 Query: 183 TFVV---RSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLD-MYLRI 238 F V R ++ AI +F RGF+ + P++ P + D + YL Sbjct: 127 PFAVMRIRDELERAIHEFFGERGFLRFDAPIL--TPSAVEGTTELFEVELFDGEKAYLSQ 184 Query: 239 APELYLKRLVVGGFERVFEINRNFRNE-GISVRHNPEFTMMELYMAYADYHDLIELTESL 297 + +LY + + F +V+ FR E + RH EF M+E +A+ + + + L E L Sbjct: 185 SGQLYAEAGAL-AFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMALQEEL 243 Query: 298 FRTLAQEVLGTTKVTYGEHVFDFGKPFE--------KLTMREAIKKYRPETDMADLDNFD 349 L VL + E + K E +LT +EA+ +A D Sbjct: 244 VSFLVARVL-ERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALV---NRIAQEDPEV 299 Query: 350 AAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDV-NP 408 E G E + ++ FD +P F+ YPA + D +P Sbjct: 300 PPLPYGEDFGAPHEAA------LSRRFD--------RPVFVERYPARIKAFYMEPDPEDP 345 Query: 409 EITDRFEFFI--GGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALE 466 E+ + G EI G ++D E + QE G E ++ + Y+ Sbjct: 346 ELVLNDDLLAPEGYGEIIGGSQRIHDLELLRRKIQE------FGLPEEVY--DWYLDLRR 397 Query: 467 YGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501 +G P +G G+G++R + +R+ I FP M Sbjct: 398 FGSVPHSGFGLGLERTVAWICGLAHVREAIPFPRM 432 >5XIX-A nrPDB Length = 472 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 78/351 (22%), Positives = 144/351 (41%), Gaps = 46/351 (13%) Query: 161 QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIPGGA 218 D +V+ R++ +I + + RS + R RG+ EV P + + GGA Sbjct: 148 SDVDVQLNNRHM-MIRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGA 206 Query: 219 SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNE-GISVRHNPEFTM 277 + + + + +L + +LYL+ + VF I +++R E + RH E+T Sbjct: 207 T----LFKLDYFGEEAFLTQSSQLYLET-CLPALGDVFCIAQSYRAEQSRTRRHLAEYTH 261 Query: 278 MELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFG-------KPFEKLTMR 330 +E + + DL+ E L + +L K G V + +PF+++ Sbjct: 262 VEAECPFLTFDDLLNRLEDLVCDVVDRIL---KSPAGSIVHELNPNFQPPKRPFKRMNYS 318 Query: 331 EAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFI 390 +AI + E D+ D E I E R++T+ +E P + Sbjct: 319 DAIV-WLKEHDVKKEDG--TFYEFGEDIPEAPE------RLMTDTINE--------PILL 361 Query: 391 TEYPAEVSPL-ARRNDVNPEITDRFEFFIGG-REIGNGFSELNDAEDQAERFQEQVNAKA 448 +P E+ +R + +T+ + + EI G + D+E+ ++ + Sbjct: 362 CRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGYKRE----- 416 Query: 449 AGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 G D +Y Y +YG P G G+G++R + N + IRDV L+P Sbjct: 417 -GIDPTPYYW--YTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP 464 >2XGT-A nrPDB Length = 435 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 74/316 (23%), Positives = 127/316 (40%), Gaps = 40/316 (12%) Query: 194 IRQFMVARGFMEVETPMM--QVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGG 251 +R+ G++EV P + + GG++ + + + +L + +LYL+ + Sbjct: 142 MREHFYNAGYVEVAPPTLVQTQVEGGST----LFNLDYFGEQSFLTQSSQLYLET-CIPT 196 Query: 252 FERVFEINRNFRNEGISVR-HNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTK 310 VF I +++R E R H E+ +E + DL+E E L +L + Sbjct: 197 LGDVFCIAQSYRAEKSRTRRHLAEYAHVEAECPFITLDDLMEKIEELVCDTVDRLLADEE 256 Query: 311 VT-YGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLG 369 EH+ +P E+ +R K DA K L E VE +G Sbjct: 257 AKKLLEHINPKFQPPERPFLRMEYK--------------DAIKWLQEH---NVENEFGNT 299 Query: 370 RIVTEIFDEVAEAHLI----QPTFITEYPAEVSPLARRNDV-NPEITDRFEFFIGGREIG 424 E E AE + +P + +P+E+ + D + +T+ + + G Sbjct: 300 FTYGEDIAEAAERFMTDTINKPILLNRFPSEIKAFYMQRDAQDNTLTESVDLLMPG---- 355 Query: 425 NGFSELNDAEDQAERFQEQVNA-KAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMI 483 E+ + +F E A K D +Y Y+ YG P G G+G++R I Sbjct: 356 --VGEIVGGSMRIWKFDELSKAFKNVEIDPKPYYW--YLDQRLYGTCPHGGYGLGLERFI 411 Query: 484 MLFTNSHTIRDVILFP 499 TN++ IRDV L+P Sbjct: 412 CWLTNTNHIRDVCLYP 427 >2ZNJ-A nrPDB Length = 308 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 42/139 (30%), Positives = 65/139 (46%), Gaps = 22/139 (15%) Query: 157 FHGLQDQEVRYRQRYLDLIANDKSRQTFV-VRSKILAAIRQFMVARGFMEVETPMMQVIP 215 F G++ Q + +R+L+ + K R + + K+ A+ Q +GF++V TP +I Sbjct: 66 FQGIEHQLMSQGKRHLEQLRTVKHRPALLELEEKLAKALHQ----QGFVQVVTPT--IIT 119 Query: 216 GGASAR-------PFITHHNALDLDMYLR--IAPELY-----LKRLVVGGFERVFEINRN 261 A A+ P + LD LR +AP LY L+RL R+FEI Sbjct: 120 KSALAKMTIGEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLWDKPI-RIFEIGTC 178 Query: 262 FRNEGISVRHNPEFTMMEL 280 +R E +H EFTM+ L Sbjct: 179 YRKESQGAQHLNEFTMLNL 197 >6JP2-A nrPDB Length = 278 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 37/106 (34%), Positives = 49/106 (46%), Gaps = 15/106 (14%) Query: 188 SKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNAL-------DLDMYLR--I 238 ++++ I +VA GF+EV TP+ I A AR IT L D LR + Sbjct: 67 TQLMNDIADALVAEGFIEVRTPIF--ISKDALARMTITEDKPLFKQVFWIDEKRALRPML 124 Query: 239 APELYLK----RLVVGGFERVFEINRNFRNEGISVRHNPEFTMMEL 280 AP LY R G ++FE+ FR E S H EFTM+ L Sbjct: 125 APNLYSVMRDLRDHTDGPVKIFEMGSCFRKESHSGMHLEEFTMLNL 170 >3P8T-A nrPDB Length = 294 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 73/331 (22%), Positives = 127/331 (38%), Gaps = 79/331 (23%) Query: 186 VRSKILAAIRQFMVARGFMEVETPMMQVI-------PGGASARPFITHHNALDLDMY--- 235 +++KIL + +F RGF + M+ I P G RP ++D+Y Sbjct: 17 IQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLWPDPAGEGIRP-------AEVDVYGVR 69 Query: 236 LRIAPELYL-KRLVVG-GFERVFEINRNFRNEGISV---RHNPEFTMMELYMAYADYHDL 290 +R+ + L K+L + G E++F ++ N R E RH+ EFT ++ + A D+ Sbjct: 70 MRLTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEGAKMKDV 129 Query: 291 IELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDA 350 + L E L L ++ E+ T RE P + ++ Sbjct: 130 MRLIEELIYGLFRKA-------------------EEWTGREF-----PRARHFKVYDY-- 163 Query: 351 AKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEI 410 K + E G DE A + +P +I P E + Sbjct: 164 -KDILEEFG----------------SDEKASMEMEEPFWIVNIPREFYDREENG-----V 201 Query: 411 TDRFEFFI--GGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYG 468 ++ + G E+ +G + E + E+ ++ A +D Y E A Sbjct: 202 WKNYDLILPYGYGEVSSG----GEREWEYEKIVAKIRAAGLKEDSFRPYLE---IARAGK 254 Query: 469 LPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 L P+AG GIG++R++ + I +V FP Sbjct: 255 LKPSAGAGIGVERLVRFIVGAKHIAEVQPFP 285 >1NNH-A nrPDB Length = 294 Score = 37.7 bits (86), Expect = 0.013, Method: Compositional matrix adjust. Identities = 75/343 (21%), Positives = 135/343 (39%), Gaps = 76/343 (22%) Query: 172 LDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALD 231 +++I+ + S T +++KIL + F V GF + ++ I P + Sbjct: 4 VEIISREIS-PTLDIQTKILEYMTDFFVKEGFKWLLPVIISPITDPLWPDPAGEGMEPAE 62 Query: 232 LDMY---LRIAPELYL-KRLVVG-GFERVFEINRNFRNEGISV---RHNPEFTMMELYMA 283 +++Y +R+ + L K+L + G +++F ++ N R E RH EFT ++ + Sbjct: 63 VEIYGVKMRLTHSMILHKQLAIAMGLKKIFVLSPNIRLESRQKDDGRHAYEFTQLDFEVE 122 Query: 284 YADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMA 343 A D++ L E L V+ + E+ T RE K R E Sbjct: 123 RAKMEDIMRLIERL-------------------VYGLFRKAEEWTGREFPKTKRFEV--- 160 Query: 344 DLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYP-----AEVS 398 F+ ++ L E G DE A + +P +I P EV Sbjct: 161 ----FEYSEVLEE-----------FGS------DEKASQEMEEPFWIINIPREFYDREVD 199 Query: 399 PLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQV-NAKAAGDDEAMFY 457 R D+ + G+ E+ ++ +++ V + AG +E F Sbjct: 200 GFWRNYDLI---------------LPYGYGEVASGGEREWEYEKIVAKIRKAGLNEDSF- 243 Query: 458 DEDYVTALEYG-LPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 Y+ + G L P+AG GIG++R++ + I +V FP Sbjct: 244 -RPYLEIAKAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFP 285 >3VQX-A nrPDB Length = 291 Score = 35.8 bits (81), Expect = 0.045, Method: Compositional matrix adjust. Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 18/135 (13%) Query: 157 FHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPG 216 F L+ + + R++ L I ++ R+ ++ K+ I +F V RGF+E+++P++ IP Sbjct: 53 FRELESELLSRRKKDLQQIYAEE-RENYL--GKLEREITRFFVDRGFLEIKSPIL--IPL 107 Query: 217 GASARPFITHHNAL-------DLDMYLR--IAPELY--LKRL--VVGGFERVFEINRNFR 263 R I + L D + LR +AP LY L++L + ++FEI +R Sbjct: 108 EYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYR 167 Query: 264 NEGISVRHNPEFTMM 278 E H EFTM+ Sbjct: 168 KESDGKEHLEEFTML 182 >3D2D-A nrPDB Length = 538 Score = 31.6 bits (70), Expect = 0.84, Method: Compositional matrix adjust. Identities = 22/89 (24%), Positives = 36/89 (40%), Gaps = 4/89 (4%) Query: 313 YGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIV 372 + E V++F KPF R Y D+ DL D + I + +SWG + Sbjct: 436 WLEKVYEFMKPFVSKNPRLG---YVNHIDL-DLGGIDWGNKTVVNNAIEISRSWGESYFL 491 Query: 373 TEIFDEVAEAHLIQPTFITEYPAEVSPLA 401 + + LI P + +P + P+A Sbjct: 492 SNYERLIRAKTLIDPNNVFNHPQSIPPMA 520 >2PME-A nrPDB Length = 693 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Query: 326 KLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHL- 384 + T+ K ++ DM ++ F + E + +E S+GLGRI+ +F+ Sbjct: 485 EFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREG 544 Query: 385 -IQPTFITEYPAEVSPL 400 Q TF + +PA V+P Sbjct: 545 DEQRTFFS-FPAVVAPF 560 >3QIB-B nrPDB Length = 202 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 6/107 (5%) Query: 325 EKLTMREAIKKYRPETDMA--DLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEA 382 E L + ++R T++ D +N+++ E V+ + R EIFD Sbjct: 40 ENLRFDSDVGEFRAVTELGRPDAENWNSQPEFLEQKRAEVDT---VCRHNYEIFDNFLVP 96 Query: 383 HLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSE 429 ++PT +T YP + PL N + ++D + I R NG E Sbjct: 97 RRVEPT-VTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEE 142 >4P2O-B nrPDB Length = 236 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 6/107 (5%) Query: 325 EKLTMREAIKKYRPETDMA--DLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEA 382 E L + ++R T++ D +N+++ E V+ + R EIFD Sbjct: 64 ENLRFDSDVGEFRAVTELGRPDAENWNSQPEFLEQKRAEVDT---VCRHNYEIFDNFLVP 120 Query: 383 HLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSE 429 ++PT +T YP + PL N + ++D + I R NG E Sbjct: 121 RRVEPT-VTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEE 166 >5GY2-A nrPDB Length = 455 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 7/82 (8%) Query: 266 GISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQ-EVLGTTKVTYGEHVF--DFGK 322 G+ +R+N + L + DY+ ++L F LA EVL T+ V +F K Sbjct: 67 GLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFK 126 Query: 323 P---FEKLTMRE-AIKKYRPET 340 P E L +R+ IKK +P + Sbjct: 127 PLTSLEMLVLRDNNIKKIQPAS 148 >3V44-A nrPDB Length = 407 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 7/90 (7%) Query: 266 GISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQ-EVLGTTKVTYGEHVF--DFGK 322 G+ +R+N + L + DY+ ++L F LA EVL T+ V +F K Sbjct: 67 GLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFK 126 Query: 323 P---FEKLTMRE-AIKKYRPETDMADLDNF 348 P E L +R+ IKK +P + ++ F Sbjct: 127 PLTSLEMLVLRDNNIKKIQPASFFLNMRRF 156 >4MNK-A nrPDB Length = 348 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 11/78 (14%) Query: 370 RIVTEIFDEVAEAHLIQPTFITEYPA-------EVSPLARRNDVNPEITDRFEFFIGGRE 422 R+ T ++ AE L PTF P + +P RR +NP + GG E Sbjct: 26 RLFTHLYYAFAE--LNAPTFEVRVPPGSEKTAEDFTPTVRR--LNPSVKTLISIGGGGSE 81 Query: 423 IGNGFSELNDAEDQAERF 440 + + F++LN +RF Sbjct: 82 VRDNFAKLNSDASARQRF 99 >1YC9-A nrPDB Length = 442 Score = 28.1 bits (61), Expect = 8.5, Method: Compositional matrix adjust. Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 5/45 (11%) Query: 438 ERFQEQVNAKAA----GDDEAMFYDEDYVTALE-YGLPPTAGLGI 477 E Q Q NA AA G D A +E ++T YGLP AG+G+ Sbjct: 211 ESIQLQKNALAALVGQGPDRAASIEEPHITLTSRYGLPSEAGVGL 255 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1LYL-A nrPDB 668 0.0 1BBU-A nrPDB 652 0.0 4EX5-A nrPDB 577 e-165 3A74-A nrPDB 551 e-157 6CHD-A nrPDB 551 e-157 6ILH-A nrPDB 547 e-156 5HGQ-A nrPDB 528 e-150 5ELO-A nrPDB 528 e-150 4YCV-A nrPDB 499 e-141 6AQG-A nrPDB 484 e-137 4UP8-A nrPDB 478 e-135 6AQH-A nrPDB 473 e-134 6NRZ-A nrPDB 459 e-129 3NEM-A nrPDB 384 e-107 1WYD-A nrPDB 376 e-104 1ASZ-A nrPDB 355 3e-98 4J15-A nrPDB 352 2e-97 1X54-A nrPDB 349 1e-96 6OD8-A nrPDB 347 5e-96 3I7F-A nrPDB 331 3e-91 1N9W-A nrPDB 330 1e-90 3M4P-A nrPDB 324 5e-89 5XIX-A nrPDB 324 5e-89 5ZG8-A nrPDB 313 1e-85 2XGT-A nrPDB 292 2e-79 3G1Z-A nrPDB 275 3e-74 3A5Z-A nrPDB 272 2e-73 4WJ3-M nrPDB 271 5e-73 1IL2-A nrPDB 265 4e-71 5W25-A nrPDB 260 9e-70 4RMF-A nrPDB 258 3e-69 1EFW-A nrPDB 241 7e-64 4AH6-A nrPDB 235 3e-62 2ZNJ-A nrPDB 94 1e-19 Sequences not found previously or not previously below threshold: 3P8T-A nrPDB 110 2e-24 1NNH-A nrPDB 108 5e-24 5GRO-A nrPDB 70 2e-12 3VQX-A nrPDB 69 4e-12 6JP2-A nrPDB 59 4e-09 3L4G-A nrPDB 46 4e-05 3TUP-A nrPDB 44 1e-04 11AS-A nrPDB 43 2e-04 4LNS-A nrPDB 43 3e-04 5LR8-A nrPDB 37 0.013 1NJ8-A nrPDB 36 0.039 5E3I-A nrPDB 35 0.065 3M8U-A nrPDB 34 0.12 1ADJ-A nrPDB 34 0.24 1R6B-X nrPDB 32 0.77 5ICJ-A nrPDB 32 0.86 2RHQ-A nrPDB 32 0.86 2Q1Z-A nrPDB 31 1.0 2ODR-C nrPDB 31 1.0 2ALY-A nrPDB 31 1.1 4FVM-A nrPDB 31 1.2 3H2D-A nrPDB 31 1.4 2W57-A nrPDB 31 1.5 1PYS-A nrPDB 31 1.7 5IQL-A nrPDB 31 1.9 2DU4-A nrPDB 31 1.9 2P0R-A nrPDB 30 2.3 3J1C-A nrPDB 29 4.4 6NHI-A nrPDB 29 5.0 3M7N-A nrPDB 29 5.6 6AH0-w nrPDB 29 5.9 5VM7-A nrPDB 28 8.9 >1LYL-A nrPDB Length = 504 Score = 668 bits (1723), Expect = 0.0, Method: Composition-based stats. Identities = 504/504 (100%), Positives = 504/504 (100%) Query: 2 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL 61 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL Sbjct: 1 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL 60 Query: 62 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI 121 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI Sbjct: 61 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI 120 Query: 122 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR 181 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR Sbjct: 121 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR 180 Query: 182 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE 241 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE Sbjct: 181 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE 240 Query: 242 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 301 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL Sbjct: 241 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 300 Query: 302 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT 361 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT Sbjct: 301 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT 360 Query: 362 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 421 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR Sbjct: 361 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 420 Query: 422 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR 481 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR Sbjct: 421 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR 480 Query: 482 MIMLFTNSHTIRDVILFPAMRPQK 505 MIMLFTNSHTIRDVILFPAMRPQK Sbjct: 481 MIMLFTNSHTIRDVILFPAMRPQK 504 >1BBU-A nrPDB Length = 504 Score = 652 bits (1681), Expect = 0.0, Method: Composition-based stats. Identities = 447/504 (88%), Positives = 478/504 (94%) Query: 2 SEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQEL 61 SEQ +GA+ +D N+EL+ RREKLA LR+QG+AFPNDFRRDHTSDQLH EFD K+N+EL Sbjct: 1 SEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDHTSDQLHAEFDGKENEEL 60 Query: 62 ESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDI 121 E+LNIEV+VAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD LPEGVYN+QFKKWDLGDI Sbjct: 61 EALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDI 120 Query: 122 IGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSR 181 +GA+G LFKT+TGELSIHCTELRLLTKALRPLPDKFHGLQDQE RYRQRYLDLI+ND+SR Sbjct: 121 LGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESR 180 Query: 182 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPE 241 TF VRS+IL+ IRQFMV RGFMEVETPMMQVIPGGA+ARPFITHHNALDLDMYLRIAPE Sbjct: 181 NTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPE 240 Query: 242 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTL 301 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADY DLIELTESLFRTL Sbjct: 241 LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTL 300 Query: 302 AQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGIT 361 AQ++LG T+VTYG+ DFGKPFEKLTMREAIKKYRPETDMADLDNFD+AKA+AESIGI Sbjct: 301 AQDILGKTEVTYGDVTLDFGKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIAESIGIH 360 Query: 362 VEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 421 VEKSWGLGRIVTEIF+EVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR Sbjct: 361 VEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGR 420 Query: 422 EIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDR 481 EIGNGFSELNDAEDQA+RF +QV AK AGDDEAMFYDEDYVTALE+GLPPTAGLGIGIDR Sbjct: 421 EIGNGFSELNDAEDQAQRFLDQVAAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDR 480 Query: 482 MIMLFTNSHTIRDVILFPAMRPQK 505 M+MLFTNSHTIRDVILFPAMRP K Sbjct: 481 MVMLFTNSHTIRDVILFPAMRPVK 504 >4EX5-A nrPDB Length = 529 Score = 577 bits (1486), Expect = e-165, Method: Composition-based stats. Identities = 289/508 (56%), Positives = 365/508 (71%), Gaps = 5/508 (0%) Query: 1 MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQE 60 M+E A A D N + RR+KL ALR QG+A+PNDF+ H + L + D + Sbjct: 22 MTEPIQPQAAVAADENQIVAERRDKLRALRDQGIAYPNDFQPTHHAADLQTAYADADKEA 81 Query: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGD 120 LE+ ++EV++AGRMM +R+MGKASF T+QD G+IQ +V + Y D FKKWDLGD Sbjct: 82 LEAKSLEVAIAGRMMLKRVMGKASFATVQDGSGQIQFFVTPADVGAETY-DAFKKWDLGD 140 Query: 121 IIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKS 180 I+ ARG LF+T GELS+ CT+LRLL KALRPLPDKFHGL DQE RYRQRY+DLI ++ Sbjct: 141 IVAARGVLFRTNKGELSVKCTQLRLLAKALRPLPDKFHGLADQETRYRQRYVDLIVTPET 200 Query: 181 RQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAP 240 R TF R+K +A+IR+FM FMEVETPM+ IPGGA+A+PF+THHNALD++M+LRIAP Sbjct: 201 RTTFRARTKAIASIRKFMGDADFMEVETPMLHPIPGGAAAKPFVTHHNALDMEMFLRIAP 260 Query: 241 ELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRT 300 ELYLKRL+VGGFERVFEINRNFRNEG+S RHNPEFTMME Y AY DY L++ TE L R Sbjct: 261 ELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTERLIRQ 320 Query: 301 LAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGI 360 A + LGT + Y D +PF +LT+ +AI+KY P L + ++ + +G+ Sbjct: 321 AAVDALGTATIQYQGRELDLAQPFHRLTITQAIQKYAPSYTDGQLSDDAFLRSELKRLGV 380 Query: 361 TVEKS----WGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEF 416 V + G+G + +F+E AEA L +PTFI +YP EVSPLAR +D IT+RFE Sbjct: 381 DVTQPAFLNAGIGALQLALFEETAEAQLWEPTFIIDYPIEVSPLARESDTVAGITERFEL 440 Query: 417 FIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLG 476 FI GREI NGFSELND EDQA RF++QV K AGD+EAMF+D DY+ ALEYG+PPT G G Sbjct: 441 FITGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCG 500 Query: 477 IGIDRMIMLFTNSHTIRDVILFPAMRPQ 504 IGIDR++ML T+S TIRDV+LFP +R + Sbjct: 501 IGIDRLVMLLTDSPTIRDVLLFPHLRRE 528 >3A74-A nrPDB Length = 493 Score = 551 bits (1420), Expect = e-157, Method: Composition-based stats. Identities = 270/490 (55%), Positives = 356/490 (72%), Gaps = 3/490 (0%) Query: 14 DFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAG 72 + ND+LR RREKL + + GV F F R H +++L E + +ELE IEV+VAG Sbjct: 4 ELNDQLRVRREKLKKIEELGVDPFGKRFERTHKAEELFELYGDLSKEELEEQQIEVAVAG 63 Query: 73 RMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQ 132 R+MT+R MGKA F +QDV G+IQ+YV +D + E Y + FK DLGDI+G RGT+FKT+ Sbjct: 64 RIMTKRGMGKAGFAHIQDVTGQIQIYVRQDDVGEQQY-ELFKISDLGDIVGVRGTMFKTK 122 Query: 133 TGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILA 192 GELSI + LTKALRPLP+K+HGL+D E RYRQRYLDLI N +S++TF+ RS I+ Sbjct: 123 VGELSIKVSSYEFLTKALRPLPEKYHGLKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQ 182 Query: 193 AIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGF 252 ++R+++ + G++EVETPMM + GGA+ARPFITHHNALD+ +Y+RIA EL+LKRL+VGG Sbjct: 183 SMRRYLDSHGYLEVETPMMHAVAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGL 242 Query: 253 ERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVT 312 E+V+EI R FRNEGIS RHNPEFTM+ELY AYAD+ D+++LTE+L +A EVLGTTK+ Sbjct: 243 EKVYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIATEVLGTTKIQ 302 Query: 313 YGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIV 372 YGEH+ D + +L M +AIK+Y D + + A+ LA+ G+ V G IV Sbjct: 303 YGEHLVDLTPEWRRLHMVDAIKEYV-GVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIV 361 Query: 373 TEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELND 432 E F++ E LIQPTFI +P E+SPLA++N +P TDRFE FI GRE N F+ELND Sbjct: 362 NEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELND 421 Query: 433 AEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTI 492 DQ +RF+EQ+ + G+DEA DED++ ALEYG+PPT GLGIG+DR++ML TNS +I Sbjct: 422 PIDQRQRFEEQLKEREQGNDEAHEMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSI 481 Query: 493 RDVILFPAMR 502 RDV+LFP MR Sbjct: 482 RDVLLFPQMR 491 >6CHD-A nrPDB Length = 597 Score = 551 bits (1419), Expect = e-157, Method: Composition-based stats. Identities = 221/511 (43%), Positives = 313/511 (61%), Gaps = 18/511 (3%) Query: 10 NEAIDFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEF-DAKDNQELESLNIE 67 E++D N + R + + L+ G +P+ F D + +++ + L +I Sbjct: 68 EESVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHL--TDIT 125 Query: 68 VSVAGRMMTRRIMG-KASFVTLQDVGGRIQLYV-ARDSLPEGVYNDQFKKWDLGDIIGAR 125 + VAGR+ +R G K F L+ G ++Q+ +R+ E + K GDIIG + Sbjct: 126 LKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQ 185 Query: 126 GTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFV 185 G KT+ GELSI E+ LL+ L LP GL+D+E RYRQRYLDLI ND RQ F+ Sbjct: 186 GNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFI 245 Query: 186 VRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLK 245 +RSKI+ IR F+ GF+E+ETPMM +IPGGA A+PFIT+HN LD+++Y+RIAPELY K Sbjct: 246 IRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHK 305 Query: 246 RLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEV 305 LVVGG +RV+EI R FRNEGI + HNPEFT E YMAYADYHDL+E+TE + + + + Sbjct: 306 MLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMVSGMVKHI 365 Query: 306 LGTTKVTYGE-------HVFDFGKPFEKLTMREAIKKYRPETDM-ADLDNFDAAKALAES 357 G+ KVTY + DF PF ++ M E ++K +L + + + + Sbjct: 366 TGSYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDD 425 Query: 358 I----GITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDR 413 I + R++ ++ E E I PTFI ++P +SPLA+ + +T+R Sbjct: 426 ICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTER 485 Query: 414 FEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTA 473 FE F+ +EI N ++ELND Q + F+EQ AKAAGDDEAMF DE++ TALEYGLPPTA Sbjct: 486 FELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTA 545 Query: 474 GLGIGIDRMIMLFTNSHTIRDVILFPAMRPQ 504 G G+GIDR+ M T+S+ I++V+LFPAM+P+ Sbjct: 546 GWGMGIDRVAMFLTDSNNIKEVLLFPAMKPE 576 >6ILH-A nrPDB Length = 521 Score = 547 bits (1410), Expect = e-156, Method: Composition-based stats. Identities = 219/509 (43%), Positives = 311/509 (61%), Gaps = 18/509 (3%) Query: 12 AIDFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEF-DAKDNQELESLNIEVS 69 ++D N + R + + L+ G +P+ F D + +++ + L +I + Sbjct: 2 SVDPNQYYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHL--TDITLK 59 Query: 70 VAGRMMTRRIMG-KASFVTLQDVGGRIQLYV-ARDSLPEGVYNDQFKKWDLGDIIGARGT 127 VAGR+ +R G K F L+ G ++Q+ +R+ E + K GDIIG +G Sbjct: 60 VAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFIHINNKLRRGDIIGVQGN 119 Query: 128 LFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVR 187 KT+ GELSI E+ LL+ L LP GL+D+E RYRQRYLDLI ND RQ F++R Sbjct: 120 PGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIR 179 Query: 188 SKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRL 247 SKI+ IR F+ GF+E+ETPMM +IPGGA A+PFIT+HN LD+++Y+RIAPELY K L Sbjct: 180 SKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKML 239 Query: 248 VVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLG 307 VVGG +RV+EI R FRNEGI + HNPEFT E YMAYADYHD +E+TE + + + + G Sbjct: 240 VVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDHMEITEKMVSGMVKHITG 299 Query: 308 TTKVTYGE-------HVFDFGKPFEKLTMREAIKKYRPETDM-ADLDNFDAAKALAESI- 358 + KVTY + DF PF ++ M E ++K +L + + + + I Sbjct: 300 SYKVTYHPDGPEGQAYDVDFTPPFRRINMVEELEKALGMKLPETNLFETEETRKILDDIC 359 Query: 359 ---GITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFE 415 + R++ ++ E E I PTFI ++P +SPLA+ + +T+RFE Sbjct: 360 VAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHPQIMSPLAKWHRSKEGLTERFE 419 Query: 416 FFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGL 475 F+ +EI N ++ELND Q + F+EQ AKAAGDDEAMF DE++ TALEYGLPPTAG Sbjct: 420 LFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGW 479 Query: 476 GIGIDRMIMLFTNSHTIRDVILFPAMRPQ 504 G+GIDR+ M T+S+ I++V+LFPAM+P+ Sbjct: 480 GMGIDRVAMFLTDSNNIKEVLLFPAMKPE 508 >5HGQ-A nrPDB Length = 524 Score = 528 bits (1361), Expect = e-150, Method: Composition-based stats. Identities = 210/512 (41%), Positives = 302/512 (58%), Gaps = 17/512 (3%) Query: 10 NEAIDFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEV 68 + D + + R + R +G+ +P+ F + ++++ + + +I Sbjct: 2 ADPSDPQEYFKLRTALINERRSKGINPYPHKFHVSISLADFIAKYNSLEKDVI-LNDIVQ 60 Query: 69 SVAGRMMTRRIMG-KASFVTLQDVGGRIQLYV-ARDSLPEGVYNDQFKKWDLGDIIGARG 126 SVAGR+ ++R G K F L G R+Q+ AR + +++ + GDIIG G Sbjct: 61 SVAGRVFSKRESGGKLIFYDLHGEGTRLQVLANARFHSGDEAFDNLHDRIKRGDIIGVNG 120 Query: 127 TLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVV 186 ++++GELSI E+ LT L LP GL++QE RYR RYLDLI N + FV Sbjct: 121 YPARSKSGELSIIPYEIIQLTPCLHMLPHTHFGLKNQETRYRMRYLDLIMNPDVKNRFVT 180 Query: 187 RSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKR 246 RS++++ +R+++ GF+EVETPMM +I GGA+A+PFITHHN LD+D+YLR+APELYLK Sbjct: 181 RSRMISFLRRYLDNLGFLEVETPMMNLIAGGATAKPFITHHNDLDMDLYLRVAPELYLKM 240 Query: 247 LVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVL 306 LVVGG +RV+EI R FRNEGI HNPEFT E YMAYADY DL+++TE + + + Sbjct: 241 LVVGGIDRVYEIGRVFRNEGIDQTHNPEFTSCEFYMAYADYEDLMKITEDMLARMVYYMH 300 Query: 307 GTTKVTYGE--------HVFDFGKPFEKLTMREAIKKYR----PETDMADLDNFDAAKA- 353 GT K+ Y + DF PF K+ + + +++ P D D D + Sbjct: 301 GTYKIQYHPNGIVENPVYEVDFTPPFRKVNIYDGLQEKLGIQFPPADTLDTDEANKFFDK 360 Query: 354 LAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDR 413 LA + R++ ++ E E I PTF+T +P +SPLA+ + P +T+R Sbjct: 361 LAVENNVECPAPRTTARLLDKLIGEFLEPTFISPTFLTGHPQIMSPLAKWHRSIPGLTER 420 Query: 414 FEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTA 473 FE F+ +EI N ++ELND Q RF EQ K AGDDEA DE+Y TALEYGLPPTA Sbjct: 421 FELFVVTKEIVNAYTELNDPLTQRLRFDEQAKQKQAGDDEAQNIDENYCTALEYGLPPTA 480 Query: 474 GLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK 505 G G+GIDR+ M+ T+S+ I++V+ FPAMRP + Sbjct: 481 GWGMGIDRLAMILTDSNNIKEVLFFPAMRPDE 512 >5ELO-A nrPDB Length = 535 Score = 528 bits (1359), Expect = e-150, Method: Composition-based stats. Identities = 193/502 (38%), Positives = 295/502 (58%), Gaps = 15/502 (2%) Query: 18 ELRNRREKLAALRQQGVA-FPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMT 76 NR + + ++ G +P+ F+ + ++ +N + + +S++GR+ + Sbjct: 23 YTDNRYKMMECIKDAGRPFYPHKFKISMSLPAYALKYGNVENGYI-DKDTTLSLSGRVTS 81 Query: 77 RRIMG-KASFVTLQDVGGRIQLYVA--RDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQT 133 R K F + ++Q+ + G ++ + GD++G G K++ Sbjct: 82 IRSSSSKLIFYDIFCEEQKVQIIANIMEHDISTGEFSVSHSEIRRGDVVGFTGFPGKSKR 141 Query: 134 GELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAA 193 GELS+ + LL+ LP GL+DQEVRYRQRYLDL+ N++SR+ F +RS+ + Sbjct: 142 GELSLFSKSVVLLSPCYHMLPTAISGLKDQEVRYRQRYLDLMLNEESRKVFKLRSRAIKY 201 Query: 194 IRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFE 253 IR + GF+EVETPM+ +I GGA+ARPFIT+HN L+ +Y+RIAPELYLK+L+VGG + Sbjct: 202 IRNYFDRLGFLEVETPMLNMIYGGAAARPFITYHNELETQLYMRIAPELYLKQLIVGGLD 261 Query: 254 RVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTY 313 +V+EI +NFRNEGI + HNPEFT ME YMAYADY+DL++LTE L L E+ G+ K+ Y Sbjct: 262 KVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYYDLMDLTEELISGLVLEIHGSLKIPY 321 Query: 314 GEH-------VFDFGKPFEKLTMREAIKKYRPETDMADLD---NFDAAKALAESIGITVE 363 DF P+++ + E I+ E LD N D + E I + Sbjct: 322 HPDGPEGKCIEIDFTTPWKRFSFVEEIESGLGEKLKRPLDSQENIDFMVEMCEKHEIELP 381 Query: 364 KSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREI 423 +++ ++ E P+FI ++P +SPLA+ + PE+T+RFE F+ G+E+ Sbjct: 382 HPRTAAKLLDKLAGHFVETKCTNPSFIIDHPQTMSPLAKWHREKPEMTERFELFVLGKEL 441 Query: 424 GNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMI 483 N ++ELN+ Q + F++Q +AKA+GD EA DE + ALE+GLPPT G G+GIDR+I Sbjct: 442 CNAYTELNEPLQQRKFFEQQADAKASGDVEACPIDETFCLALEHGLPPTGGWGLGIDRLI 501 Query: 484 MLFTNSHTIRDVILFPAMRPQK 505 M + + I++VILFPAMR K Sbjct: 502 MFLADKNNIKEVILFPAMRNVK 523 >4YCV-A nrPDB Length = 516 Score = 499 bits (1284), Expect = e-141, Method: Composition-based stats. Identities = 207/507 (40%), Positives = 296/507 (58%), Gaps = 19/507 (3%) Query: 13 IDFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEF-DAKDNQELESLNIEVSV 70 +D NR + + + +G+ +P+ F R + + E++ D + + LE + +++ Sbjct: 3 VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLE--DTILNI 60 Query: 71 AGRMMTRRIMG-KASFVTLQDVGGRIQLYV--ARDSLPEGVYNDQFKKWDLGDIIGARGT 127 GR+M G K F L G +IQ+ + + +G + + + K GDI+G G Sbjct: 61 TGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGF 120 Query: 128 LFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVR 187 K++ GELSI E LL+ L LP K+ GL+D E+RYRQRYLDL+ N+ SR TFV R Sbjct: 121 PGKSKKGELSIFPKETILLSACLHMLPMKY-GLKDTEIRYRQRYLDLLINESSRHTFVTR 179 Query: 188 SKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRL 247 +KI+ +R F+ RGF EVETPMM +I GGA+ARPFITHHN LDLD+YLRIA EL LK L Sbjct: 180 TKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKML 239 Query: 248 VVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLG 307 +VGG ++V+EI + FRNEGI HNPEFT E Y AYADY+DLI+ +E F L + G Sbjct: 240 IVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFG 299 Query: 308 TTKVTYGEH-------VFDFGKPFEKLTMREAIKKYRPETDMADLDN---FDAAKALAES 357 T K++Y + DF P+ K+++ E I+K D+ + + + Sbjct: 300 TYKISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKE 359 Query: 358 IGITVEKSWGLGRIVTEIFDEVAEAHLIQ-PTFITEYPAEVSPLARRNDVNPEITDRFEF 416 I + +++ ++ E P FI E+P +SPLA+ + P +T+R E Sbjct: 360 HKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLAKYHRTKPGLTERLEM 419 Query: 417 FIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLG 476 FI G+E+ N ++ELND Q E F+ Q + GD EA D + T+LEYGLPPT GLG Sbjct: 420 FICGKEVLNAYTELNDPFKQKECFKLQQKDREKGDTEAAQLDSAFCTSLEYGLPPTGGLG 479 Query: 477 IGIDRMIMLFTNSHTIRDVILFPAMRP 503 +GIDR+ M TN ++I+DVILFP MRP Sbjct: 480 LGIDRITMFLTNKNSIKDVILFPTMRP 506 >6AQG-A nrPDB Length = 506 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 194/502 (38%), Positives = 299/502 (59%), Gaps = 11/502 (2%) Query: 9 ANEAIDFNDELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEF-DAKDNQELESLNI 66 ++ + ++ R RR+K A L +G +P R HT ++ + D + E + Sbjct: 10 SSAESNIPEQFRIRRDKRARLLAEGYDPYPVAIERTHTLAEIRATYADLPTDSATEDI-- 67 Query: 67 EVSVAGRMMTRRIMGKASFVTLQDVGG-RIQLYVARDSLPEGVYNDQFKKWDLGDIIGAR 125 V VAGR++ R GK F TLQD G ++Q ++ D + + D+GD++ Sbjct: 68 -VGVAGRVVFARNTGKLCFATLQDGDGTQLQAMISLDEVGRESLDRWKADVDIGDVVYVH 126 Query: 126 GTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFV 185 GT+ ++ GELS+ R+ KALRPLP H +E R RQRY+DLI ++R+ Sbjct: 127 GTVISSRRGELSVLADSWRMAAKALRPLPVA-HKEMSEESRVRQRYVDLIVRPQAREVAR 185 Query: 186 VRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLK 245 R ++ A+R + RGF+EVETPM+Q + GGA+ARPF+TH NALD+D+YLRIAPEL+LK Sbjct: 186 QRIAVIRAVRNALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFLK 245 Query: 246 RLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEV 305 R +VGGF+RVFE+NR FRNEG H+PEF+M+E Y Y Y D +T L + +A E Sbjct: 246 RCIVGGFDRVFELNRVFRNEGSDSTHSPEFSMLETYQTYGTYDDSALITRELIQEVADEA 305 Query: 306 LGTTKVTYGE-HVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEK 364 +GT +++ + V+D + + M ++ + E + +A + + ++ Sbjct: 306 IGTRQLSMPDGSVYDIDGEWATMEMYSSLSEALGEQITP-ETTVARLRDIASGLDVEIDN 364 Query: 365 S-WGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREI 423 S +G G++V E+++ L PTF+ ++P E +PL R++ P +T++++ ++ G E+ Sbjct: 365 SVFGHGKLVEELWEHAVGNKLTAPTFVKDFPVETTPLTRQHRSIPGVTEKWDLYVRGVEL 424 Query: 424 GNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMI 483 G+SELND Q +RF +Q A AAGDDEAM DED++TALEYG+PP G G+GIDR++ Sbjct: 425 ATGYSELNDPVVQRDRFADQARAAAAGDDEAMQLDEDFLTALEYGMPPCTGTGMGIDRLL 484 Query: 484 MLFTNSHTIRDVILFPAMRPQK 505 M T +IR+ +LFP +RP Sbjct: 485 MCLTGL-SIRETVLFPIVRPHS 505 >4UP8-A nrPDB Length = 777 Score = 478 bits (1230), Expect = e-135, Method: Composition-based stats. Identities = 202/561 (36%), Positives = 304/561 (54%), Gaps = 75/561 (13%) Query: 17 DELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMM 75 NR + + ++ G +P+ F T + ++ + ++ + VSVAGR++ Sbjct: 12 QLFLNRCKDVEEYQKAGHNPWPHKFNVSITVPEFIAKYSGLEKSQVS--DDIVSVAGRVL 69 Query: 76 TRRIMGK-ASFVTLQDVGGRIQLYVARDSLP-EGVYNDQFKKWDLGDIIGARGTLFKTQT 133 ++R F+ L D ++Q+ + + + + + K GDI G G +T+T Sbjct: 70 SKRSSSSALMFIDLHDSQTKLQIMLNKSAYENKEDFVSLTKMIYRGDICGFTGHPTRTKT 129 Query: 134 GELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAA 193 GELS+ +L+ L LP +GL DQE R+R+RYLDLI N +S + FV+R+K++ A Sbjct: 130 GELSLIPISGMILSPCLHMLPSMHYGLGDQETRFRKRYLDLIVNPESVKNFVLRTKVVKA 189 Query: 194 IRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFE 253 +R+++ +GF+EVETP++ IPGGA+ARPFITHHN LD+ MY+RIAPELYLK LVVGG Sbjct: 190 VRKYLDDKGFLEVETPILNTIPGGATARPFITHHNQLDIQMYMRIAPELYLKELVVGGIN 249 Query: 254 RVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVL-GTTKVT 312 RV+EI R FRNEGI HNPEFT E YMAYADY+D++++TE L + +++ G+TK+ Sbjct: 250 RVYEIGRLFRNEGIDQTHNPEFTTCEFYMAYADYNDIMKMTEELLGNMVKDITGGSTKLE 309 Query: 313 YGEHVFD-----------------FGKPFEKLTMREAIKKYRPETD-MADLDNFDAAK-- 352 + + D +PF + I+K+ E + D +N A K Sbjct: 310 IKDRLMDINNEEDIKMLEKFFKEPIPRPFNSAECSKVIEKHCTELNYYYDGNNEKAMKKL 369 Query: 353 -------------------------ALAESIGITVEK----------------------- 364 AL E G + + Sbjct: 370 FADFVTEKKMVLDFTAPFKRISYVHALEEKFGEKIPRPLDGPEALTFLKKQAIRFNAICA 429 Query: 365 -SWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREI 423 R++ ++F ++ E L+QPTF+ + P +SPLA+ + PE+T+RFE FI REI Sbjct: 430 EPQTTARVMDKLFGDLIEVDLVQPTFVCDQPQLMSPLAKYHRSEPELTERFELFILKREI 489 Query: 424 GNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMI 483 N ++ELN+ Q F++Q KAAGDDEA DE ++ A+E+ PPT G G+GIDR+ Sbjct: 490 ANAYTELNNPIVQRSNFEQQAKDKAAGDDEAQLVDEVFLDAIEHAFPPTGGWGLGIDRLA 549 Query: 484 MLFTNSHTIRDVILFPAMRPQ 504 ML + I++VILFP MRP+ Sbjct: 550 MLLADVDNIKEVILFPTMRPE 570 >6AQH-A nrPDB Length = 508 Score = 473 bits (1217), Expect = e-134, Method: Composition-based stats. Identities = 196/504 (38%), Positives = 297/504 (58%), Gaps = 10/504 (1%) Query: 6 TRGANEAIDFNDELRNRREKLAALRQQG-VAFPNDFRRDHTSDQLHEEFDAKDNQELESL 64 T + D ++ R R+ K A L QG +P D R HT ++ + + Sbjct: 10 TPPESVDPDLPEQFRIRQAKRADLLAQGRQPYPVDVPRTHTLLEIRQAYPDLPVDA--RT 67 Query: 65 NIEVSVAGRMMTRRIMGKASFVTLQDVGG-RIQLYVARDSLPEGVYNDQFKKWDLGDIIG 123 V V GR++ R GK F TLQ+ G ++Q ++ + + ++ D+GDI+ Sbjct: 68 GEIVGVTGRVVFARNSGKLCFATLQEGDGTQLQAMISLAEVGQEALDNWKTYVDIGDIVF 127 Query: 124 ARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQT 183 G + ++ GELS+ ++ KALRPLP H +E R RQRY+DLI D++R+ Sbjct: 128 VHGEVITSKRGELSVLADSWQMAAKALRPLPVA-HKEMSEESRVRQRYVDLIVRDQARKV 186 Query: 184 FVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELY 243 R ++ AIR + RGF+EVETPM+Q + GGA+ARPF+TH NALD ++YLRIAPEL+ Sbjct: 187 ARQRIAVMRAIRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDTELYLRIAPELF 246 Query: 244 LKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQ 303 LKR +VGGFERVFE+NR FRNEG H+PEF M+E Y AY Y D +T L + +A Sbjct: 247 LKRCLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQAYGTYDDSAVVTRELIQEVAD 306 Query: 304 EVLGTTKVTYGE-HVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITV 362 E +GT +V + V+D +E + M ++ + E D + A+A+ +G+ + Sbjct: 307 EAIGTRQVPLPDGTVYDLDGEWESIQMYPSLSEALGEEITPD-TPAETLWAIADRLGLDI 365 Query: 363 E--KSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGG 420 + +G G++V E+++ A L PTF+ ++P E +PL R + P +T++++ ++ Sbjct: 366 PRDRGYGHGKLVEELWEHTVGAKLWAPTFVKDFPVETTPLTRSHRSIPGVTEKWDLYVRR 425 Query: 421 REIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGID 480 E+ G+SEL D Q ERF+ Q A AAGDDEAM DED++ ALEYG+PP+ G G+GID Sbjct: 426 IELATGYSELTDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGMPPSTGTGMGID 485 Query: 481 RMIMLFTNSHTIRDVILFPAMRPQ 504 R++M T +IR+ +LFP ++P+ Sbjct: 486 RLMMTLTGL-SIRETVLFPIVKPR 508 >6NRZ-A nrPDB Length = 534 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 197/511 (38%), Positives = 298/511 (58%), Gaps = 27/511 (5%) Query: 17 DELRNRREKLAALRQQGV-AFPNDFRRDHTSDQLHEEFDAKDNQELESL----NIEVSVA 71 ++ R KL +R G+ +P + ++ +F + + E+ +V A Sbjct: 19 EDYLYRTSKLKEIRDLGINPYPYQYTDCLEVQEIRNQFVDNELGDSEAAFRKETPKVRFA 78 Query: 72 GRMMTRRIMGKASFVTLQDVGGRIQLYVARD-------SLPEGVYNDQF--KKWDLGDII 122 GR++ R MGK +F + D +IQ+ RD + G+ +F KK DLGDI+ Sbjct: 79 GRLVLFRSMGKNAFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIEKKLDLGDIL 138 Query: 123 GARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQ 182 G G LF T +GEL++ + LL K+L LPDK GL D+E+RYR+R+ DLI+++ R+ Sbjct: 139 GLEGYLFFTHSGELTVLVETVTLLCKSLISLPDKHAGLADKEIRYRKRWADLISSEDVRK 198 Query: 183 TFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPEL 242 TF+ RS+IL IR++M + F+EVETP++Q + GGA A PF+T AL +M+LRI+ E+ Sbjct: 199 TFLTRSRILKLIREYMDQQSFLEVETPILQTVYGGAEATPFVTTLQALHAEMFLRISLEI 258 Query: 243 YLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLA 302 LK+L+VGG RV+EI + FRNEGI HNPEFTM+E Y AY DY+D+++ E+L + Sbjct: 259 ALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAAYWDYNDVMKCVENLVEYIV 318 Query: 303 QEV-LGTTKVTY-----GEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAE 356 + + G T+V Y G V DF P+ ++TM+E+I Y DL + + E Sbjct: 319 RALNNGETQVQYSHLKSGPQVVDFKAPWIRMTMKESISVYGGVD--VDLHADHELRKILE 376 Query: 357 SIGITVEKSWGL---GRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPE-ITD 412 + EK++ G ++ +FDE+ LI P IT++P E +PL + E + + Sbjct: 377 TQTSLPEKTYVHASRGELIALLFDELVCDKLIAPHHITDHPLETTPLCKTLRSGDETLVE 436 Query: 413 RFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDD-EAMFYDEDYVTALEYGLPP 471 RFE F G+E+ N +SELND Q + +EQ+ KA D E DE+++ AL G+PP Sbjct: 437 RFESFCLGKELCNAYSELNDPLQQRKLLEEQMRKKALNPDSEYHPIDEEFLEALCQGMPP 496 Query: 472 TAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 G GIGIDR++M+ T++ +IRDV+ FP MR Sbjct: 497 AGGFGIGIDRLVMMLTDAASIRDVLFFPVMR 527 >3NEM-A nrPDB Length = 438 Score = 384 bits (987), Expect = e-107, Method: Composition-based stats. Identities = 114/471 (24%), Positives = 194/471 (41%), Gaps = 50/471 (10%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H S ++ EE + + +V VAG + + +G F+ ++D G +Q+ + Sbjct: 3 RTHYSSEITEELNGQ----------KVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPK 52 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGEL--SIHCTELRLLTKALRPLPDKFHG 159 + ++ K D++ G + T +L I ++ +L +A PLP G Sbjct: 53 KKVDPELF-KLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTG 111 Query: 160 LQDQE--VRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGG 217 E R R++DL + F +RS + A+R F GF+E+ TP + Sbjct: 112 KVKAELDTRLDNRFMDL-RRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATAT- 169 Query: 218 ASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNE-GISVRHNPEFT 276 + + D +L +P+LY + ++ G +RV+EI FR E + RH E Sbjct: 170 -EGGTELFPMKYFEEDAFLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAW 228 Query: 277 MMELYMAYA-DYHDLIELTESLFRTLAQEVLGTTKVTY---GEHVFDFGKPFEKLTMREA 332 ++ MA+ D +++ E L V + + PF +++ +A Sbjct: 229 SIDSEMAFIEDEEEVMSFLERLVAHAINYVREHNAKELDILNFELEEPKLPFPRVSYDKA 288 Query: 333 IKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE 392 ++ D K + I E LG+ + E +E A F+ + Sbjct: 289 LEILG-----------DLGKEIPWGEDIDTEGERLLGKYMME--NENAPL-----YFLYQ 330 Query: 393 YPAEVSPLA-RRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGD 451 YP+E P + D PEI F+ G EI +G E + + EQ+ K Sbjct: 331 YPSEAKPFYIMKYDNKPEICRAFDLEYRGVEISSGGQR----EHRHDILVEQIKEKGLNP 386 Query: 452 DEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 + F Y+ A YG+PP G G+G +R+I + IR+VILFP R Sbjct: 387 ESFEF----YLKAFRYGMPPHGGFGLGAERLIKQMLDLPNIREVILFPRDR 433 >1WYD-A nrPDB Length = 429 Score = 376 bits (965), Expect = e-104, Method: Composition-based stats. Identities = 117/474 (24%), Positives = 212/474 (44%), Gaps = 61/474 (12%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H + E+D K EV AG + R +G F+ L+D G Q+ V + Sbjct: 3 RSHFIADVTPEYDGK----------EVIWAGWVHLLRDLGGKKFIILRDKTGLGQVVVDK 52 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTG--ELSIHCTELRLLTKALRPLPDKFHG 159 +S G+ + +I RG + + + +H E+ LL+KA PLP G Sbjct: 53 NSSAFGISQE----LTQESVIQVRGIVKADKRAPRGIELHAEEITLLSKAKAPLPLDVSG 108 Query: 160 L--QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETP--MMQVIP 215 D + R R+R LDL + + ++S L A R+ + GF+E+ TP + Sbjct: 109 KVKADIDTRLRERVLDL-RRQEMQAVIKIQSLALKAFRETLYKEGFIEIFTPKIIASATE 167 Query: 216 GGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV-RHNPE 274 GGA P I + +L +P+LY + L+ G ERVFE+ +R E H E Sbjct: 168 GGAQLFPVI----YFGKEAFLAQSPQLYKE-LMAGVVERVFEVAPAWRAEESDTPFHLAE 222 Query: 275 FTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGK---PFEKLTMRE 331 F M++ MA+ADY+D+++L E + + + + K ++ + P ++L E Sbjct: 223 FISMDVEMAFADYNDVMQLLEKILHNIVKTIKEEGKEELKILNYEPPEVKIPIKRLKYTE 282 Query: 332 AIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFIT 391 AI+ + S G ++ +G I +E + L FI Sbjct: 283 AIE-------------------ILRSKGYNIKFGDDIGTPELRILNEELKEDL---YFIV 320 Query: 392 EYPAEVSPLARRN-DVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG 450 ++P++ P ++ NPE+++ F+ EI +G + + + E +E + K Sbjct: 321 DWPSDARPFYTKSKSENPELSESFDLIYKFLEIVSGSTRNH----KREVLEEALKKKGLK 376 Query: 451 DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQ 504 + F ++ +YG+PP AG G+G+ R++++ T ++++++ FP + + Sbjct: 377 PESFEF----FLKWFDYGMPPHAGFGMGLARLMVMLTGIQSVKEIVPFPRDKKR 426 >1ASZ-A nrPDB Length = 490 Score = 355 bits (910), Expect = 3e-98, Method: Composition-based stats. Identities = 119/483 (24%), Positives = 199/483 (41%), Gaps = 67/483 (13%) Query: 57 DNQELESLNIEVSVAGRMMTRRIMGK-ASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKK 115 D E + + EV R+ R G +F+TL+ IQ V + EG + K Sbjct: 31 DLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANK--EGTISKNMVK 88 Query: 116 W----DLGDIIGARGTLFKTQ-------TGELSIHCTELRLLTKALRPLPDKFHGLQDQE 164 W +L I+ RG + K L IH T++ +++ LP E Sbjct: 89 WAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSE 148 Query: 165 --------------VRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPM 210 R R +DL ++ F +++ + R+++ + F EV TP Sbjct: 149 AEAEAAGLPVVNLDTRLDYRVIDL-RTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPK 207 Query: 211 MQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV- 269 + P + F YL +P+ ++L+V FERV+EI FR E + Sbjct: 208 LLGAPSEGGSSVF--EVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTH 265 Query: 270 RHNPEFTMMELYMAYAD-YHDLIELTESLFRTLAQEV-------LGTTKVTYGEHVFDFG 321 RH EFT +++ MA+ + YH++++ LF + E+ + + Y F Sbjct: 266 RHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLP 325 Query: 322 K--PFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEV 379 K +LT +E I+ R A K + + ++ E LG++V + +D Sbjct: 326 KDGKMVRLTYKEGIEMLRA-----------AGKEIGDFEDLSTENEKFLGKLVRDKYD-- 372 Query: 380 AEAHLIQPTFITEYPAEVSPLARRNDV-NPEITDRFEFFIGGREIGNGFSELNDAEDQAE 438 + ++P E+ P D NP+ ++ ++FF+ G EI +G ++D E Sbjct: 373 -----TDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQE 427 Query: 439 RFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILF 498 R KA G +DY YG PP AG GIG++R++M + + IR LF Sbjct: 428 RM------KAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLF 481 Query: 499 PAM 501 P Sbjct: 482 PRD 484 >4J15-A nrPDB Length = 521 Score = 352 bits (902), Expect = 2e-97, Method: Composition-based stats. Identities = 108/472 (22%), Positives = 190/472 (40%), Gaps = 60/472 (12%) Query: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGD 120 ++ + V V R+ T R GK F+ L+ +Q VA + Sbjct: 73 IQKADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANINKES 132 Query: 121 IIGARGTLFKTQT-------GELSIHCTELRLLTKALRPLPDKFHGLQ------------ 161 I+ G + K ++ +H ++ +++ A LP + Sbjct: 133 IVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEAEGEEEGRA 192 Query: 162 --DQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGAS 219 +Q+ R R +DL S+ F ++S I R+ ++ +GF+E++TP + Sbjct: 193 TVNQDTRLDNRVIDL-RTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGG 251 Query: 220 ARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV-RHNPEFTMM 278 A F + + YL +P+LY + + FE+VF I FR E + RH EF + Sbjct: 252 ANVFT--VSYFKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGL 309 Query: 279 ELYMAY-ADYHDLIELTESLFRTL-------AQEVLGTTKVTYGEHVFDFGKPFEKLTMR 330 ++ MA+ YH+++E + Q + T + F F +P +L Sbjct: 310 DIEMAFNYHYHEVMEEIADTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYC 369 Query: 331 EAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFI 390 EA+ R +A + + ++ LG +V E +D + Sbjct: 370 EALAMLR-----------EAGVEMGDEDDLSTPNEKLLGHLVKEKYD-------TDFYIL 411 Query: 391 TEYPAEVSPLARRNDV-NPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAA 449 +YP V P D NP+ ++ ++ F+ G EI +G ++D + ER A Sbjct: 412 DKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTER------ALHH 465 Query: 450 GDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501 G D + Y+ + +G PP AG GIG++R+ MLF H +R +FP Sbjct: 466 GIDLEKI--KAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRD 515 >1X54-A nrPDB Length = 434 Score = 349 bits (896), Expect = 1e-96, Method: Composition-based stats. Identities = 101/466 (21%), Positives = 182/466 (39%), Gaps = 54/466 (11%) Query: 45 TSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSL 104 ++ E D K +V +AG + T +GK F+ ++D G +Q VA++ + Sbjct: 6 YCQEVKPELDGK----------KVRLAGWVYTNMRVGKKIFLWIRDSTGIVQAVVAKNVV 55 Query: 105 PEGVYNDQFKKWDLGDIIGARGTLFKT--QTGELSIHCTELRLLTKALR-PLPDKFHGLQ 161 E + ++ KK + G + G +H +L ++ P+P+ Sbjct: 56 GEETF-EKAKKLGRESSVIVEGIVKADERAPGGAEVHVEKLEVIQAVSEFPIPENPEQ-A 113 Query: 162 DQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASAR 221 E+ R+L I K+ V+ ++ A R++++ G+ EV P++ + G Sbjct: 114 SPELLLDYRHLH-IRTPKASAIMKVKETLIMAAREWLLKDGWHEVFPPIL--VTGAVEGG 170 Query: 222 PFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVR-HNPEFTMMEL 280 + D YL + +LYL+ + G E+V+ + +FR E R H EF +EL Sbjct: 171 ATLFKLKYFDKYAYLSQSAQLYLEAAIF-GLEKVWSLTPSFRAEKSRTRRHLTEFWHLEL 229 Query: 281 YMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFG------KPFEKLTMREAIK 334 A+ D D++++ E L + Q L K D PF +++ EAI Sbjct: 230 EAAWMDLWDIMKVEEELVSYMVQRTLELRKKEIEMFRDDLTTLKNTEPPFPRISYDEAI- 288 Query: 335 KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYP 394 + +S G+ VE LG + E +P F+ YP Sbjct: 289 ------------------DILQSKGVNVEWGDDLGADEERVLTEE----FDRPFFVYGYP 326 Query: 395 AEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEA 454 + + D N D + G+ E+ + + + + +N + Sbjct: 327 KHIKAFYMKEDPN----DPRKVLASDMLAPEGYGEIIGGSQREDDYDKLLNRILEEGMDP 382 Query: 455 MFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPA 500 Y E Y+ YG P +G G+G++R++ IR LFP Sbjct: 383 KDY-EWYLDLRRYGSVPHSGFGLGVERLVAWVLKLDHIRWAALFPR 427 >6OD8-A nrPDB Length = 558 Score = 347 bits (891), Expect = 5e-96, Method: Composition-based stats. Identities = 119/554 (21%), Positives = 213/554 (38%), Gaps = 79/554 (14%) Query: 1 MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQE 60 MS++E R A + + + + A P + S + Sbjct: 25 MSDKEARKAARLAEEKARADEKAALVEKYKAVFGAAPMVQSTTYKS---RTHIPVSELSR 81 Query: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGD 120 E ++ V + R+ T R GK +F+ L+D +Q A + D + Sbjct: 82 PELVDKTVLIRARVSTTRKKGKMAFMVLRDGSDSVQAMAAVEGDVPKEMIDFMGQIATES 141 Query: 121 IIGARGTLFK-------TQTGELSIHCTELRLLTKALRPLPDKFHGLQDQE--------- 164 I+ T+ K T ++ + ++ +T++LR LP +E Sbjct: 142 IVDVEATVCKVEQPITSTSHSDIELKVKKIHTVTESLRTLPFTLEDASRKESAEGAKVNL 201 Query: 165 -VRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPF 223 R R++DL S F ++S++ RQF++ + F E+ +P + P A F Sbjct: 202 DTRLNSRWMDL-RTLASGAIFRLQSRVCQYFRQFLIDKDFCEIHSPKIINAPSEGGANVF 260 Query: 224 ITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV-RHNPEFTMMELYM 282 + YL +P+LY + ++ G RVFE+ FR+E + RH EF +++ M Sbjct: 261 --KLEYFNRFAYLAQSPQLYKQMVLQGDVPRVFEVGPVFRSENSNTHRHLTEFVGLDVEM 318 Query: 283 AYAD-YHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMR---EAIKKY-- 336 + Y++++++ ESLF + + + TK PFE L + E IK+ Sbjct: 319 RIDEHYYEVLDVAESLFNYIFERLATHTKELKNVCQ---QYPFEPLVWKLTPERIKELGV 375 Query: 337 -----------RPETDMADLDN-----------------FDAAKALAESIGITVEKSWGL 368 + + + ++D+ D A + I T EK L Sbjct: 376 GVISEGVVPTDKFQARVHNMDSRMLRINYMHCIELLNTVLDEKMAPTDDINTTNEK--LL 433 Query: 369 GRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLA-RRNDVNPEITDRFEFFIGGREIGNGF 427 G++V E + +P+ P + T+ ++ FI G EI +G Sbjct: 434 GKLVKERYG-------TDFFISDRFPSSARPFYTMECKDDVRFTNSYDMFIRGEEISSGA 486 Query: 428 SELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFT 487 ++D + R AK D ++YV + G P G GIG++R++ML+ Sbjct: 487 QRIHDPDLLLAR------AKMLNVDLTPI--KEYVDSFRLGAWPHGGFGIGLERVVMLYL 538 Query: 488 NSHTIRDVILFPAM 501 +R LFP Sbjct: 539 GLSNVRLASLFPRD 552 >3I7F-A nrPDB Length = 548 Score = 331 bits (849), Expect = 3e-91, Method: Composition-based stats. Identities = 111/510 (21%), Positives = 197/510 (38%), Gaps = 102/510 (20%) Query: 65 NIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGA 124 V++ R+ R G F+ L+ Q V + + +K I Sbjct: 62 EKTVTIRARVQAVRGKGNMVFLFLRKGIYTCQALVMKSETISKEFVQFCQKISAESICDI 121 Query: 125 RGTLFKTQT-------GELSIHCTELRLLTKA---------------------------- 149 G + + ++ IH T + +++ A Sbjct: 122 TGIVKAVEKPIEKATQQDVEIHVTSIAVVSLAEYPLPMQIEDLTFPSSVFKKQEEDIAKV 181 Query: 150 -----------------LRPLPDKFHGL------------QDQEVRYRQRYLDLIANDKS 180 RPL D++ L Q+ R R LDL + Sbjct: 182 DEKIAKFLKDNEGKDLTKRPLKDEYAKLLKEKASAQKYVKVSQDTRLDNRMLDL-RTVTN 240 Query: 181 RQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAP 240 F ++S R+F+ ++ F+E+ TP + I + I D YL +P Sbjct: 241 IAIFRIQSACCGLFREFLTSQKFVEIHTPKL--IGCSSEGGSNIFEVKYFDRKAYLAQSP 298 Query: 241 ELYLKRLVVGGFERVFEINRNFRNEGI-SVRHNPEFTMMELYMAYAD-YHDLIELTESLF 298 +LY + ++G F +VFE+ FR E + RH EF +++ M + YH+ I++ E LF Sbjct: 299 QLYKQMAIMGDFRKVFEVGPVFRAENSNTRRHLTEFEGLDIEMEIVENYHECIDVMEKLF 358 Query: 299 RTLAQEV----LGTTKVTYGEHVFD--FGKPFEKLTMREAIKKYRPETDMADLDNFDAAK 352 + E+ KV ++ F+ +PF +LT +EAI+ R + Sbjct: 359 TFIFDEIPKRFPDELKVIRKQYPFEDLIYRPFLRLTYKEAIEMLRASGET---------- 408 Query: 353 ALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRND-VNPEIT 411 + + T + LG ++ ++ + ++PA + P D +P + Sbjct: 409 -IGDYDDFTTPQEVKLGELIKAKYN-------TDFYILDKFPAAIRPFYTMPDIDDPNYS 460 Query: 412 DRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPP 471 + ++ F+ G+EI +G ++D E +R E+ G D A +DY+ + +G P Sbjct: 461 NSYDVFVRGQEITSGAQRIHDPEFLMKRCIEK------GVDPATL--KDYIESFRFGSWP 512 Query: 472 TAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501 AG GIG++R+ ML+ IR V LFP Sbjct: 513 HAGCGIGLERITMLYLGIPNIRKVTLFPRD 542 >1N9W-A nrPDB Length = 422 Score = 330 bits (845), Expect = 1e-90, Method: Composition-based stats. Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 51/453 (11%) Query: 59 QELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDL 118 + EV + G + RR +G+ F+ L+D G +Q+ LP Sbjct: 7 DLKAHVGQEVELLGFLHWRRDLGRIQFLLLRDRSGVVQVVTGGLKLP-----------LP 55 Query: 119 GDIIGARGTLFKTQ--TGELSIHCTELRLLTKALRPLP---DKFHGLQDQEVRYRQRYLD 173 + RG + + G L + E+ +L+ AL P P K + + RY+ Sbjct: 56 ESALRVRGLVVENAKAPGGLEVQAKEVEVLSPALEPTPVEIPKEEWRANPDTLLEYRYVT 115 Query: 174 LIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLD 233 L +K+R V++ ++ R+++ + F E+ TP +V+ GA + + + Sbjct: 116 L-RGEKARAPLKVQAALVRGFRRYLDRQDFTEIFTP--KVVRAGAEGGSGLFGVDYFEKR 172 Query: 234 MYLRIAPELYLKRLVVGGFERVFEINRNFR-NEGISVRHNPEFTMMELYMAY-ADYHDLI 291 YL +P+LY + ++VG FERV+E+ +R E + RH E+ +++ M + AD DL+ Sbjct: 173 AYLAQSPQLYKQ-IMVGVFERVYEVAPVWRMEEHHTSRHLNEYLSLDVEMGFIADEEDLM 231 Query: 292 ELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAA 351 L E+L + +E L T G+ + G + D+ L + +A Sbjct: 232 RLEEALLAEMLEEALNTA----GDEIRLLGATWPSFPQ-----------DIPRLTHAEAK 276 Query: 352 KALAESIGITVEK--SWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPE 409 + L E +G V + S R++ E E + + F+T YP V P + + Sbjct: 277 RILKEELGYPVGQDLSEEAERLLGEYAKERWGSDWL---FVTRYPRSVRPFYTYPEED-G 332 Query: 410 ITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGL 469 T F+ G EI +G ++ E+ E KA G D F+ Y+ +YG+ Sbjct: 333 TTRSFDLLFRGLEITSGGQRIHRYEELLESL------KAKGMDPEAFHG--YLEVFKYGM 384 Query: 470 PPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 PP G IG +R+ +R FP R Sbjct: 385 PPHGGFAIGAERLTQKLLGLPNVRYARAFPRDR 417 >3M4P-A nrPDB Length = 456 Score = 324 bits (831), Expect = 5e-89, Method: Composition-based stats. Identities = 91/457 (19%), Positives = 173/457 (37%), Gaps = 46/457 (10%) Query: 59 QELESLNIEVSVAGRMMTRRIMGK-ASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWD 117 V+ G R K FV L+D G Q + L E + Sbjct: 24 DAAGLEGKLVTFKGWAYHIRKARKTLIFVELRDGSGYCQCVIFGKELCEPEKVKLLTREC 83 Query: 118 LGDIIG-ARGTLFKTQTGE------LSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQR 170 +I G K E L + TE +++ ++ L + + + + R Sbjct: 84 SLEITGRLNAYAGKNHPPEIADILNLEMQVTEWKVIGESPIDLENIINKDSSIPQKMQNR 143 Query: 171 YLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNAL 230 ++ +I ++ ++Q +RS+I R++ F E++ P + + + Sbjct: 144 HI-VIRSEHTQQVLQLRSEIQWYFRKYYHDNHFTEIQPPTIVKTQCEGGST--LFKLQYF 200 Query: 231 DLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV-RHNPEFTMMELYMAYADYHD 289 + YL + +LYL+ V+ + F + ++R E RH E+ +E + + + D Sbjct: 201 NEPAYLTQSSQLYLES-VIASLGKSFCMLSSYRAEQSRTVRHLAEYLHLEAELPFISFED 259 Query: 290 LIELTESLFRTLAQEVL---GTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLD 346 L+ E L T+ V+ G H+ +PF+++T +AIK + + Sbjct: 260 LLNHLEDLVCTVIDNVMAVHGDKIRKMNPHLKLPTRPFKRMTYADAIKY----CNDHGIL 315 Query: 347 NFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLAR-RND 405 N D E I E+ + P F+ +P+++ + Sbjct: 316 NKDKPFEYGEDISEKPERQMT--------------DEIGCPIFMIHFPSKMKAFYMSKVP 361 Query: 406 VNPEITDRFEFFIGGR-EIGNGFSELNDAEDQAERFQEQVNA-KAAGDDEAMFYDEDYVT 463 +P++T+ + + G EI G + + E + A KA G + +Y Y Sbjct: 362 GHPDLTESVDLLMPGVGEIVGGSMRI-------WNYDELMGAYKANGLNPDPYYW--YTQ 412 Query: 464 ALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPA 500 +YG P G G+G++R++M IR V L+P Sbjct: 413 QRKYGSCPHGGYGLGVERLVMWLLGEDHIRKVCLYPR 449 >5XIX-A nrPDB Length = 472 Score = 324 bits (830), Expect = 5e-89, Method: Composition-based stats. Identities = 101/470 (21%), Positives = 174/470 (37%), Gaps = 51/470 (10%) Query: 47 DQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGK-ASFVTLQDVGGRIQLYVARDSLP 105 L E K V V G + R GK F+ L+D G +Q +A Sbjct: 31 PSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLA----D 86 Query: 106 EGVYNDQFKKWDLGDIIGARGTL-----FKTQTGELSIHCTELRLLTKALRPLPDKF-HG 159 E + G L K G + C L+ A D + Sbjct: 87 ELCQCYNGVLLSTESSVAVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLINE 146 Query: 160 LQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM--QVIPGG 217 D +V+ R++ +I + + RS + R RG+ EV P + + GG Sbjct: 147 ESDVDVQLNNRHM-MIRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGG 205 Query: 218 ASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNE-GISVRHNPEFT 276 A+ + + + +L + +LYL+ + VF I +++R E + RH E+T Sbjct: 206 AT----LFKLDYFGEEAFLTQSSQLYLETCL-PALGDVFCIAQSYRAEQSRTRRHLAEYT 260 Query: 277 MMELYMAYADYHDLIELTESLFRTLAQEVL----GTTKVTYGEHVFDFGKPFEKLTMREA 332 +E + + DL+ E L + +L G+ + +PF+++ +A Sbjct: 261 HVEAECPFLTFDDLLNRLEDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDA 320 Query: 333 IKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE 392 I + E D+ D E I E R++T+ +E P + Sbjct: 321 I-VWLKEHDVKKEDG--TFYEFGEDIPEAPE------RLMTDTINE--------PILLCR 363 Query: 393 YPAEVSPLAR-RNDVNPEITDRFEFFIGGR-EIGNGFSELNDAEDQAERFQEQVNAKAAG 450 +P E+ R + +T+ + + EI G + D+E+ + K G Sbjct: 364 FPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGY------KREG 417 Query: 451 DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPA 500 D +Y Y +YG P G G+G++R + N + IRDV L+P Sbjct: 418 IDPTPYYW--YTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPR 465 >5ZG8-A nrPDB Length = 438 Score = 313 bits (801), Expect = 1e-85, Method: Composition-based stats. Identities = 102/461 (22%), Positives = 183/461 (39%), Gaps = 51/461 (11%) Query: 58 NQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKK 115 ++ ++ EV + G + RR GK F+ L+D G +Q V + +PE V+ D + Sbjct: 6 DEIARHVDQEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQ 65 Query: 116 WDLGDIIGARGTLFKTQTGELSIHCTELRLLTKAL--RPLPDKFHGLQDQEVRYRQRYLD 173 + G R + G + +L+++++ P+ K HG+ D + +R +L Sbjct: 66 ETALRVWG-RVREDRRAPGGFELAVRDLQVVSRPQGEYPIGPKEHGI-DFLMDHRHLWLR 123 Query: 174 LIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLD 233 +R ++ AI +F RGF+ + P++ P + D + Sbjct: 124 HRRPF---AVMRIRDELERAIHEFFGERGFLRFDAPIL--TPSAVEGTTELFEVELFDGE 178 Query: 234 -MYLRIAPELYLKRLVVGGFERVFEINRNFRNE-GISVRHNPEFTMMELYMAYADYHDLI 291 YL + +LY + + F +V+ FR E + RH EF M+E +A+ + + + Sbjct: 179 KAYLSQSGQLYAEAGALA-FAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENM 237 Query: 292 ELTESLFRTLAQEVLGTTKVTYGEHVFDFGKP--------FEKLTMREAIKKYRPETDMA 343 L E L L VL + E + K + +LT +EA+ +A Sbjct: 238 ALQEELVSFLVARVL-ERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALV---NRIA 293 Query: 344 DLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARR 403 D E G E + ++ FD +P F+ YPA + Sbjct: 294 QEDPEVPPLPYGEDFGAPHEAA------LSRRFD--------RPVFVERYPARIKAFYME 339 Query: 404 NDV-NPEITDRFEFFIG--GREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDED 460 D +PE+ + EI G ++D E + QE G E ++ + Sbjct: 340 PDPEDPELVLNDDLLAPEGYGEIIGGSQRIHDLELLRRKIQE------FGLPEEVY--DW 391 Query: 461 YVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501 Y+ +G P +G G+G++R + +R+ I FP M Sbjct: 392 YLDLRRFGSVPHSGFGLGLERTVAWICGLAHVREAIPFPRM 432 >2XGT-A nrPDB Length = 435 Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats. Identities = 94/462 (20%), Positives = 168/462 (36%), Gaps = 52/462 (11%) Query: 56 KDNQELESLNIEVSVAGRMMTRRIMGK-ASFVTLQDVGGRIQLYVARDSLPEGVYNDQFK 114 K ++ N V + G + R GK F L+D G +Q+ + D L + Sbjct: 2 KIRDLVKHRNERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLLM-DKLCQTYDALTVN 60 Query: 115 KWDLGDIIGA--RGTLFKTQTGELSIHCTELRLLTKALRP-LPDKFHGLQDQEVRYRQRY 171 +I GA K + +++ A + + + + R+ Sbjct: 61 TECTVEIYGAIKEVPEGKEAPNGHELIADFWKIIGNAPPGGIDNVLNEEASVDKMLDNRH 120 Query: 172 LDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALD 231 L +I + + +R+ A+R+ G++EV P + + + + + Sbjct: 121 L-VIRGENAAALLRLRAAATRAMREHFYNAGYVEVAPPTLVQTQVEGGST--LFNLDYFG 177 Query: 232 LDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVR-HNPEFTMMELYMAYADYHDL 290 +L + +LYL+ + VF I +++R E R H E+ +E + DL Sbjct: 178 EQSFLTQSSQLYLETCI-PTLGDVFCIAQSYRAEKSRTRRHLAEYAHVEAECPFITLDDL 236 Query: 291 IELTESLFRTLAQEVLGTTKVT-----YGEHVFDFGKPFEKLTMREAIKKYRPETDMADL 345 +E E L +L + +PF ++ ++AI Sbjct: 237 MEKIEELVCDTVDRLLADEEAKKLLEHINPKFQPPERPFLRMEYKDAI------------ 284 Query: 346 DNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQ----PTFITEYPAEVSPLA 401 K L E VE +G E E AE + P + +P+E+ Sbjct: 285 ------KWLQEH---NVENEFGNTFTYGEDIAEAAERFMTDTINKPILLNRFPSEIKAFY 335 Query: 402 RRNDV-NPEITDRFEFFIGGR-EIGNGFSELNDAEDQAERFQEQVNA-KAAGDDEAMFYD 458 + D + +T+ + + G EI G + +F E A K D +Y Sbjct: 336 MQRDAQDNTLTESVDLLMPGVGEIVGGSMRI-------WKFDELSKAFKNVEIDPKPYYW 388 Query: 459 EDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPA 500 Y+ YG P G G+G++R I TN++ IRDV L+P Sbjct: 389 --YLDQRLYGTCPHGGYGLGLERFICWLTNTNHIRDVCLYPR 428 >3G1Z-A nrPDB Length = 326 Score = 275 bits (704), Expect = 3e-74, Method: Composition-based stats. Identities = 105/334 (31%), Positives = 169/334 (50%), Gaps = 32/334 (9%) Query: 180 SRQTFVVRSKILAAIRQFMVARGFMEVETPMM-QVIPGGASARPFITHH----NALDLDM 234 S + R+ I+A IR+F RG +EVETP M Q PF T ++ +++ Sbjct: 13 SIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGINL 72 Query: 235 YLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELT 294 YL +PE ++KRL+ G VF++ R+FRNE + HNPEFTM+E Y + D + L+ Sbjct: 73 YLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEV 132 Query: 295 ESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFD----A 350 + L + + +P E L+ ++A +++ E D D A Sbjct: 133 DDLLQQVLD-----------------CQPAESLSYQQAFQRHL-EIDPLSADKTQLREAA 174 Query: 351 AKALAESIGITVEKSWGLGRIVTEIFDEVAEAHL--IQPTFITEYPAEVSPLARRNDVNP 408 AK +I T E L ++ +F E H+ +PTFI +PA + LA+ + + Sbjct: 175 AKLDLSNIADTEEDRDTLLQL---LFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDH 231 Query: 409 EITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYG 468 + +RFE + G E+ NGF EL DA +Q +RF++ +AA D++ + AL G Sbjct: 232 RVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQQPIDQNLLDALAAG 291 Query: 469 LPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 LP +G+ +G+DR++ML + ++ DVI F R Sbjct: 292 LPDCSGVALGVDRLVMLALGAESLADVIAFTVDR 325 >3A5Z-A nrPDB Length = 328 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 101/334 (30%), Positives = 168/334 (50%), Gaps = 32/334 (9%) Query: 180 SRQTFVVRSKILAAIRQFMVARGFMEVETPMM-QVIPGGASARPFITHH----NALDLDM 234 S + R+ I+A IR+F RG +EVETP M Q PF T ++ +++ Sbjct: 15 SIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNL 74 Query: 235 YLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELT 294 +L +PE ++KRL+V G VF++ R+FRNE + HNPEFTM+E Y + D + L+ Sbjct: 75 WLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEV 134 Query: 295 ESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFD----A 350 + L + + E L+ ++A +Y E D D A Sbjct: 135 DDLLQQVLD-----------------CPAAESLSYQQAFLRYL-EIDPLSADKTQLREVA 176 Query: 351 AKALAESIGITVEKSWGLGRIVTEIFDEVAEAHL--IQPTFITEYPAEVSPLARRNDVNP 408 AK ++ T E L ++ +F E ++ +PTF+ +PA + LA+ + + Sbjct: 177 AKLDLSNVADTEEDRDTLLQL---LFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDH 233 Query: 409 EITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYG 468 + +RFE + G E+ NGF EL DA +Q +RF++ +AA D++ + AL+ G Sbjct: 234 RVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVG 293 Query: 469 LPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 +P +G+ +G+DR++ML + T+ +VI F R Sbjct: 294 MPDCSGVALGVDRLVMLALGAETLAEVIAFSVDR 327 >4WJ3-M nrPDB Length = 599 Score = 271 bits (692), Expect = 5e-73, Method: Composition-based stats. Identities = 82/326 (25%), Positives = 148/326 (45%), Gaps = 35/326 (10%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H QL+E D + EV++ G + RR G F+ ++D G Q+ Sbjct: 11 RSHYCGQLNESLDGQ----------EVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDP 60 Query: 102 DSLPEGVYNDQFKKWDLGDIIG-AR-----GTLFKTQTGELSIHCTELRLLTKALRP-LP 154 D D+ + + I G R +G + + EL +L +A P P Sbjct: 61 DRAETFAKADRVRSEFVVKITGKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFP 120 Query: 155 DKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM-QV 213 + +E R R R++DL + +R++I ++IR+++ GF++VETP++ + Sbjct: 121 LDEYSDVGEETRLRYRFIDL-RRPEMAAKLKLRARITSSIRRYLDDNGFLDVETPILGRP 179 Query: 214 IPGGASARPFITHHNALDLDMY-LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHN 272 P GA R ++ + L +P+L+ + L+V GF+R ++I + FR+E + Sbjct: 180 TPEGA--RDYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQ 237 Query: 273 PEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREA 332 PEFT +++ ++ D D+I +TE + R L +EVL F + EA Sbjct: 238 PEFTQIDIETSFLDESDIIGITEKMVRQLFKEVLDVE-----------FDEFPHMPFEEA 286 Query: 333 IKKYRPETDMADLDNFDAAKALAESI 358 +++Y +D DL +A+ + Sbjct: 287 MRRY--GSDKPDLRIPLELVDVADQL 310 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 34/148 (22%), Positives = 66/148 (44%), Gaps = 5/148 (3%) Query: 352 KALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEIT 411 + + + + + + +F+E + L P +P + ++ Sbjct: 422 IKVGHDLKLLTREWAPMWVVDFPMFEENDDGSLSALHHPFTSPK-CTPAELEANPGAALS 480 Query: 412 DRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPP 471 ++ + G E+G G ++D Q F+ +A +++ F + AL+YG PP Sbjct: 481 RAYDMVLNGTELGGGSIRIHDKSMQQAVFRVLGIDEAEQEEKFGFL----LDALKYGAPP 536 Query: 472 TAGLGIGIDRMIMLFTNSHTIRDVILFP 499 GL G+DR++ML T + +IR+VI FP Sbjct: 537 HGGLAFGLDRLVMLMTGASSIREVIAFP 564 >1IL2-A nrPDB Length = 590 Score = 265 bits (676), Expect = 4e-71, Method: Composition-based stats. Identities = 80/323 (24%), Positives = 144/323 (44%), Gaps = 35/323 (10%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R QL L + +V++ G + RR +G F+ ++D G +Q++ Sbjct: 2 RTEYCGQLR----------LSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDP 51 Query: 102 DSLPEGVYNDQFKKWDLGDIIGA------RGTLFKTQTGELSIHCTELRLLTKALRPLPD 155 D + + + G + TGE+ + + L ++ +A LP Sbjct: 52 DRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRA-DVLPL 110 Query: 156 KFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM-QVI 214 + + +E R + RYLDL + Q R+KI + +R+FM GF+++ETPM+ + Sbjct: 111 DSNHVNTEEARLKYRYLDL-RRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKAT 169 Query: 215 PGGASARPFITHHNALDLDMY-LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNP 273 P GA R ++ Y L +P+L+ + L++ GF+R ++I + FR+E + P Sbjct: 170 PEGA--RDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQP 227 Query: 274 EFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAI 333 EFT +++ ++ + E+ E+L R L EV G F +T EA Sbjct: 228 EFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGV-----------DLGDFPVMTFAEAE 276 Query: 334 KKYRPETDMADLDNFDAAKALAE 356 ++Y +D DL N +A+ Sbjct: 277 RRY--GSDKPDLRNPMELTDVAD 297 Score = 146 bits (368), Expect = 2e-35, Method: Composition-based stats. Identities = 40/148 (27%), Positives = 67/148 (45%), Gaps = 5/148 (3%) Query: 353 ALAESIGITVEKSWG-LGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEIT 411 + + +G+T E W L I +F++ E L P +++ + + Sbjct: 412 KVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVA 471 Query: 412 DRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPP 471 + ++ I G E+G G +++ + Q F ++E + AL+YG PP Sbjct: 472 NAYDMVINGYEVGGGSVRIHNGDMQQTVFGIL----GINEEEQREKFGFLLDALKYGTPP 527 Query: 472 TAGLGIGIDRMIMLFTNSHTIRDVILFP 499 AGL G+DR+ ML T + IRDVI FP Sbjct: 528 HAGLAFGLDRLTMLLTGTDNIRDVIAFP 555 >5W25-A nrPDB Length = 616 Score = 260 bits (664), Expect = 9e-70, Method: Composition-based stats. Identities = 86/332 (25%), Positives = 143/332 (43%), Gaps = 40/332 (12%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H + L E +V++AG + RR G F+ L+D G Q+ R Sbjct: 25 RSHAAGLLRE----------GDAGQQVTLAGWVARRRDHGGVIFIDLRDASGIAQVVF-R 73 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTL---------FKTQTGELSIHCTELRLLTKALRP 152 D V Q + + G + + TGE+ ++ T L +L + P Sbjct: 74 DPQDTEVLA-QAHRLRAEFCVSVAGVVEIRPEGNANPEIATGEIEVNATSLTVLGECA-P 131 Query: 153 LPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM- 211 LP + +E+R + RYLDL +D + +RS++ AA R + F+E+ETP + Sbjct: 132 LPFQLDEPAGEELRLKYRYLDLRRDDPAAAI-RLRSRVNAAARAVLARHDFVEIETPTIT 190 Query: 212 QVIPGGASARPFITHHNALDLDMY-LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVR 270 + P GA R F+ Y L +P+L+ + L+V G ER ++I R +R+E Sbjct: 191 RSTPEGA--RDFLVPARLHPGSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRAD 248 Query: 271 HNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMR 330 PEFT +++ M++ D D+I ++E EVL G + P ++ Sbjct: 249 RQPEFTQLDMEMSFVDAEDIIAISE--------EVLTELWALIG---YRIPTPIPRIGYA 297 Query: 331 EAIKKYRPETDMADLDNFDAAKALAESIGITV 362 EA++++ TD DL + T Sbjct: 298 EAMRRF--GTDKPDLRFGLELVECTDFFSDTT 327 Score = 111 bits (277), Expect = 7e-25, Method: Composition-based stats. Identities = 35/162 (21%), Positives = 57/162 (35%), Gaps = 16/162 (9%) Query: 350 AAKALAESIGITVEKSWGL-GRIVTEIFDEVAEAH-----------LIQPTFITEYPAEV 397 A +A +G+ +W + +F+ EA P Sbjct: 423 ARVEIANRLGLIDPDAWAFVWVVDPPLFEPADEATAAGEVAVGSGAWTAVHHAFTAPKPE 482 Query: 398 SPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFY 457 +D + D ++ G EIG G ++ + Q F KA +++ F Sbjct: 483 WEDRIESDTGSVLADAYDIVCNGHEIGGGSVRIHRRDIQERVFAVMGLDKAEAEEKFGFL 542 Query: 458 DEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 + A +G PP G+ G DR L +IR+VI FP Sbjct: 543 ----LEAFMFGAPPHGGIAFGWDRTTALLAGMDSIREVIAFP 580 >4RMF-A nrPDB Length = 609 Score = 258 bits (660), Expect = 3e-69, Method: Composition-based stats. Identities = 77/332 (23%), Positives = 139/332 (41%), Gaps = 43/332 (12%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H + L V++AG + RR G F+ L+D G Q+ Sbjct: 3 RTHAAGSLRPA----------DAGQTVTLAGWVARRRDHGGVIFIDLRDASGVSQVVFRE 52 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTL---------FKTQTGELSIHCTELRLLTKALRP 152 + + + G + + TG++ ++ TEL +L ++ P Sbjct: 53 GDVLAAA-----HRLRAEFCVAVTGVVEVRPEGNENPEIPTGQIEVNATELTVLGESA-P 106 Query: 153 LPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMM- 211 LP + +E R + RYLDL + +RSK+ AA R + F+E+ETP + Sbjct: 107 LPFQLDEQAGEEARLKYRYLDL-RREGPGNALRLRSKVNAAARSVLAEHDFVEIETPTLT 165 Query: 212 QVIPGGASARPFITHHNALDLDMY-LRIAPELYLKRLVVGGFERVFEINRNFRNEGISVR 270 + P GA R F+ Y L +P+L+ + L+V G ER ++I R +R+E Sbjct: 166 RSTPEGA--RDFLVPARLQPGSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRAD 223 Query: 271 HNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMR 330 PEFT +++ M++ + D+I ++E + + + + +D P +++ Sbjct: 224 RQPEFTQLDMEMSFVEADDVIAISEQVLKAVWATI-----------GYDLPLPLPRISYE 272 Query: 331 EAIKKYRPETDMADLDNFDAAKALAESIGITV 362 EA++++ +D DL E T Sbjct: 273 EAMRRF--GSDKPDLRFGIELVECTEYFKDTT 302 Score = 121 bits (302), Expect = 1e-27, Method: Composition-based stats. Identities = 35/160 (21%), Positives = 56/160 (35%), Gaps = 16/160 (10%) Query: 352 KALAESIGITVEKSWGL-GRIVTEIFDEVAEAH-----------LIQPTFITEYPAEVSP 399 +A+ + + +W + +F+ EA P S Sbjct: 400 IEIAKRLDLIDPNAWAFTWVVDFPMFEAADEATAAGDVAVGSGAWTAMHHAFTAPKPDSV 459 Query: 400 LARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDE 459 +D ++D ++ G EIG G ++ + Q F DEA Sbjct: 460 DTFDSDPGNALSDAYDIVCNGNEIGGGSIRIHRRDIQERVFAMMGIDH----DEAQEKFG 515 Query: 460 DYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 + A YG PP G+ G DR+ L +IR+VI FP Sbjct: 516 FLLDAFSYGAPPHGGIAFGWDRITALLAGVDSIREVIAFP 555 >1EFW-A nrPDB Length = 580 Score = 241 bits (614), Expect = 7e-64, Method: Composition-based stats. Identities = 83/330 (25%), Positives = 150/330 (45%), Gaps = 43/330 (13%) Query: 41 RRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVA 100 RR H + L E + EV + G + RR +G F+ L+D G +Q VA Sbjct: 2 RRTHYAGSLRET----------HVGEEVVLEGWVNRRRDLGGLIFLDLRDREGLVQ-LVA 50 Query: 101 RDSLPEGVYNDQFKKWDLGDIIGARGTLF-------KTQTGELSIHCTELRLLTKALRPL 153 + P + + ++ A+G + + TG + + + L +L +A P Sbjct: 51 HPASPAYATAE---RVRPEWVVRAKGLVRLRPEPNPRLATGRVEVELSALEVLAEAKTPP 107 Query: 154 PDKFHGLQDQEVRYRQRYLDL------IANDKSRQTFVVRSKILAAIRQFMVARGFMEVE 207 G + +E + L L + + ++ +R +++ AI F+ GF++VE Sbjct: 108 FPVDAGWRGEEEKEASEELRLKYRYLDLRRRRMQENLRLRHRVIKAIWDFLDREGFVQVE 167 Query: 208 TPMM-QVIPGGASARPFITHH-NALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNE 265 TP + + P GA R F+ + + L L +P+L+ + L+V G +R F+I R FR+E Sbjct: 168 TPFLTKSTPEGA--RDFLVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRDE 225 Query: 266 GISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFE 325 + P+FT ++L M++ + D++EL E L + +E LG + PF Sbjct: 226 DLRADRQPDFTQLDLEMSFVEVEDVLELNERLMAHVFREALG----------VELPLPFP 275 Query: 326 KLTMREAIKKYRPETDMADLDNFDAAKALA 355 +L+ EA+++Y +D DL K + Sbjct: 276 RLSYEEAMERY--GSDKPDLRFGLELKEVG 303 Score = 112 bits (281), Expect = 3e-25, Method: Composition-based stats. Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 5/149 (3%) Query: 355 AESIGITVEKSWGLGRIVTEIFD-EVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDR 413 A+ +G+ E L + + + + E P D Sbjct: 408 ADLLGLKREGFRFLWVVDFPLLEWDEEEEAWTYMHHPFTSPHPEDLPLLEKDPGRVRALA 467 Query: 414 FEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTA 473 ++ + G E+G G ++D QA F G++E ++ ALEYG PP Sbjct: 468 YDLVLNGVEVGGGSIRIHDPRLQARVF----RLLGIGEEEQREKFGFFLEALEYGAPPHG 523 Query: 474 GLGIGIDRMIMLFTNSHTIRDVILFPAMR 502 G+ G+DR++ L T S +IR+VI FP + Sbjct: 524 GIAWGLDRLLALMTGSPSIREVIAFPKNK 552 >4AH6-A nrPDB Length = 617 Score = 235 bits (599), Expect = 3e-62, Method: Composition-based stats. Identities = 75/316 (23%), Positives = 139/316 (43%), Gaps = 44/316 (13%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R +T +L L EV++ G + RR + +F+ L+D G +Q+ + + Sbjct: 11 RTNTCGELRSS----------HLGQEVTLCGWIQYRR---QNTFLVLRDFDGLVQVIIPQ 57 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLF---------KTQTGELSIHCTELRLLTKALRP 152 D V + + ++ GT+ K TGE+ I LL + Sbjct: 58 DESAASV-KKILCEAPVESVVQVSGTVISRPAGQENPKMPTGEIEIKVKTAELLNACKK- 115 Query: 153 LPDKFHGL--QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVA-RGFMEVETP 209 LP + + + +R + RYLDL + + + +RS+++ +R+++ GF+++ETP Sbjct: 116 LPFEIKNFVKKTEALRLQYRYLDL-RSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETP 174 Query: 210 MM-QVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGIS 268 + + PGGA + F+ L +P+ + + L+VGG +R F++ R +R+EG Sbjct: 175 TLFKRTPGGA--KEFLVPSREPGKFYSLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSR 232 Query: 269 VRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLT 328 PEFT +++ M++ D + L E L + ++ PF +T Sbjct: 233 PDRQPEFTQIDIEMSFVDQTGIQSLIEGLLQY-----------SWPNDKDPVVVPFPTMT 281 Query: 329 MREAIKKYRPETDMAD 344 E + Y TD D Sbjct: 282 FAEVLATY--GTDKPD 295 Score = 108 bits (270), Expect = 6e-24, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 9/111 (8%) Query: 389 FITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKA 448 F +P+++ L + ++ + G EIG G +++AE Q + Sbjct: 465 FTAPHPSDIHLLYTE--PKKARSQHYDLVLNGNEIGGGSIRIHNAELQRYILATLLK--- 519 Query: 449 AGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFP 499 E + + AL+YG PP G+ +G+DR+I L T S +IRDVI FP Sbjct: 520 ----EDVKMLSHLLQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFP 566 >3P8T-A nrPDB Length = 294 Score = 110 bits (274), Expect = 2e-24, Method: Composition-based stats. Identities = 64/339 (18%), Positives = 126/339 (37%), Gaps = 69/339 (20%) Query: 175 IANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVI-------PGGASARPFITHH 227 I + + +++KIL + +F RGF + M+ I P G RP Sbjct: 6 IISRDIYKAIDIQTKILDYMTKFFTDRGFKWLLPIMLSPITDPLWPDPAGEGIRP--AEV 63 Query: 228 NALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISV---RHNPEFTMMELYMAY 284 + + M L + L+ + + G E++F ++ N R E RH+ EFT ++ + Sbjct: 64 DVYGVRMRLTHSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEIEG 123 Query: 285 ADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMAD 344 A D++ L E L L ++ + F + F+ ++ ++++ Sbjct: 124 AKMKDVMRLIEELIYGLFRKA-----EEWTGREFPRARHFKVYDYKDILEEFGS------ 172 Query: 345 LDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRN 404 DE A + +P +I P E + Sbjct: 173 --------------------------------DEKASMEMEEPFWIVNIPREF-----YD 195 Query: 405 DVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQE-QVNAKAAGDDEAMFYDEDYVT 463 + ++ + G+ E++ ++ +++ +AAG E F Y+ Sbjct: 196 REENGVWKNYDLILPY-----GYGEVSSGGEREWEYEKIVAKIRAAGLKEDSF--RPYLE 248 Query: 464 ALEYG-LPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501 G L P+AG GIG++R++ + I +V FP + Sbjct: 249 IARAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFPRV 287 >1NNH-A nrPDB Length = 294 Score = 108 bits (270), Expect = 5e-24, Method: Composition-based stats. Identities = 60/339 (17%), Positives = 118/339 (34%), Gaps = 69/339 (20%) Query: 175 IANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVI-----PGGASARPFITHHNA 229 I + + T +++KIL + F V GF + ++ I P A Sbjct: 6 IISREISPTLDIQTKILEYMTDFFVKEGFKWLLPVIISPITDPLWPDPAGEGMEPAEVEI 65 Query: 230 LDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGI---SVRHNPEFTMMELYMAYAD 286 + M L + L+ + + G +++F ++ N R E RH EFT ++ + A Sbjct: 66 YGVKMRLTHSMILHKQLAIAMGLKKIFVLSPNIRLESRQKDDGRHAYEFTQLDFEVERAK 125 Query: 287 YHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLD 346 D++ L E L L ++ + F K FE E ++++ Sbjct: 126 MEDIMRLIERLVYGLFRKA-----EEWTGREFPKTKRFEVFEYSEVLEEFGS-------- 172 Query: 347 NFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDV 406 DE A + +P +I P E + Sbjct: 173 ------------------------------DEKASQEMEEPFWIINIPREF-----YDRE 197 Query: 407 NPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQE---QVNAKAAGDDEAMFYDEDYVT 463 ++ + G+ E+ ++ +++ ++ +D Y+ Sbjct: 198 VDGFWRNYDLILPY-----GYGEVASGGEREWEYEKIVAKIRKAGLNEDSFRP----YLE 248 Query: 464 ALEYG-LPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501 + G L P+AG GIG++R++ + I +V FP + Sbjct: 249 IAKAGKLKPSAGAGIGVERLVRFIVGAKHIAEVQPFPRI 287 >2ZNJ-A nrPDB Length = 308 Score = 94.4 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 18/163 (11%) Query: 156 KFHGLQDQEVRYRQRYLDLIANDKSRQTFV-VRSKILAAIRQFMVARGFMEVETPMMQVI 214 F G++ Q + +R+L+ + K R + + K+ A+ Q +GF++V TP + Sbjct: 65 AFQGIEHQLMSQGKRHLEQLRTVKHRPALLELEEKLAKALHQ----QGFVQVVTPTIITK 120 Query: 215 PGGASAR-----PFITHHNALDLDMYLR--IAPELY-----LKRLVVGGFERVFEINRNF 262 A P + LD LR +AP LY L+RL R+FEI + Sbjct: 121 SALAKMTIGEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLWDKPI-RIFEIGTCY 179 Query: 263 RNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEV 305 R E +H EFTM+ L + + E + R + + Sbjct: 180 RKESQGAQHLNEFTMLNLTELGTPLEERHQRLEDMARWVLEAA 222 Score = 29.7 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 28/243 (11%), Positives = 72/243 (29%), Gaps = 32/243 (13%) Query: 279 ELYMAYADY----HDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK 334 +L M ++D + L + + V + + + + K ++ Sbjct: 51 QLEMGFSDALSRDRAFQGIEHQLMSQGKRHLEQLRTVKHRPALLELEEKLAKALHQQGFV 110 Query: 335 KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGR-IVTEIFDEVAEAHLIQPTFITEY 393 + T + + A + E + + W G+ + + + + + Sbjct: 111 QVVTPTII--TKSALAKMTIGEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLWDK 168 Query: 394 PA---EVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDA--EDQAERFQEQVNAKA 448 P E+ R+ + + F E+G E + + + + Sbjct: 169 PIRIFEIGTCYRKESQGAQHLNEFTML-NLTELGTPLEERHQRLEDMARWVLEAAGIREF 227 Query: 449 AGDDEAMFYDEDYVTALEY-------GLPPT------------AGLGIGIDRMIMLFTNS 489 E+ D V ++ + P GLG G++R++M+ + Sbjct: 228 ELVTESSVVYGDTVDVMKGDLELASGAMGPHFLDEKWEIFDPWVGLGFGLERLLMIREGT 287 Query: 490 HTI 492 + Sbjct: 288 QHV 290 >5GRO-A nrPDB Length = 115 Score = 70.2 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 45/117 (38%), Gaps = 23/117 (19%) Query: 42 RDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVAR 101 R H ++ E + + V VAG T R G F+ L+D G +QL Sbjct: 13 RSHFCTEISE----------KDVGKIVKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCD- 61 Query: 102 DSLPEGVYNDQFKKWDLGDIIGARGTLF---------KTQTGELSIHCTELRLLTKA 149 P ++ + ++ A+G + K +TG++ I EL + K+ Sbjct: 62 ---PSSKAYEKALEVRSEFVLVAKGKVRLRGAGLENPKLKTGKIEIVLEELIIENKS 115 >3VQX-A nrPDB Length = 291 Score = 69.0 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 34/135 (25%), Positives = 61/135 (45%), Gaps = 14/135 (10%) Query: 157 FHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIP- 215 F L+ + + R++ L I ++ K+ I +F V RGF+E+++P++ + Sbjct: 53 FRELESELLSRRKKDLQQIYAEERENYL---GKLEREITRFFVDRGFLEIKSPILIPLEY 109 Query: 216 ----GGASARPFITHHNALDLDMYLR--IAPELY--LKRL--VVGGFERVFEINRNFRNE 265 G + +D + LR +AP LY L++L + ++FEI +R E Sbjct: 110 IERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKE 169 Query: 266 GISVRHNPEFTMMEL 280 H EFTM+ Sbjct: 170 SDGKEHLEEFTMLNF 184 >6JP2-A nrPDB Length = 278 Score = 59.0 bits (141), Expect = 4e-09, Method: Composition-based stats. Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 13/105 (12%) Query: 188 SKILAAIRQFMVARGFMEVETPMMQVIPGGA-----SARPFITHHNALDLDMYLR--IAP 240 ++++ I +VA GF+EV TP+ A +P +D LR +AP Sbjct: 67 TQLMNDIADALVAEGFIEVRTPIFISKDALARMTITEDKPLFKQVFWIDEKRALRPMLAP 126 Query: 241 ELY-----LKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMEL 280 LY L+ G ++FE+ FR E S H EFTM+ L Sbjct: 127 NLYSVMRDLRDHTDGPV-KIFEMGSCFRKESHSGMHLEEFTMLNL 170 >3L4G-A nrPDB Length = 508 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Query: 254 RVFEINRNFRNEGISVRHNPEFTMMELYMA--YADYHDLIELTESLFRTLAQEVLGTTKV 311 + F I+R FRNE + H EF +E +A L+ + F LG T++ Sbjct: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTK-----LGITQL 403 Query: 312 TYGEHVFDFGKP-FEKLTMREAIKKYRPETDMA 343 + + +P E + + +KK+ + Sbjct: 404 RFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSG 436 >3TUP-A nrPDB Length = 415 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 33/249 (13%), Positives = 67/249 (26%), Gaps = 83/249 (33%) Query: 247 LVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVL 306 L+ G + + +R + I +H P F +E ++ + LF + Sbjct: 127 LLHAGLDAFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKH--------ELFAGIKD--- 175 Query: 307 GTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSW 366 E+++ + + A +A+ + + Sbjct: 176 -----------------------GESLQLFEQSSRSAHKQETHTMEAV---KLVEFDLKQ 209 Query: 367 GLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNG 426 L R++ +F + E + F +P FE I Sbjct: 210 TLTRLMAHLFGDELEIRWVDCYFPFTHP------------------SFEMEINFH----- 246 Query: 427 FSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGL--GIGIDRMIM 484 E + G E + G G G+G++R+ M Sbjct: 247 --------------GEWLEVLGCGVMEQQLVNSA-------GAQDRIGWAFGLGLERLAM 285 Query: 485 LFTNSHTIR 493 + + IR Sbjct: 286 ILYDIPDIR 294 >11AS-A nrPDB Length = 330 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 61/348 (17%), Positives = 116/348 (33%), Gaps = 67/348 (19%) Query: 180 SRQTFVVRSKILAAIRQFMVAR-----GFMEVETPMMQVIPGGASARPFITHHNALDLDM 234 + ++ + + ++ ++ + G +EV+ P++ + G T N + Sbjct: 1 MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDG-------TQDNLSGAEK 53 Query: 235 YLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPE----FTMME----------- 279 A ++ +K L FE V + + ++ + + +T M+ Sbjct: 54 ----AVQVKVKALPDAQFEVVHSLAK-WKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSP 108 Query: 280 ---LYMAYADYHDLIELTESLFRTLAQEV------LGTTKVTYGEHVFDFGKPFEKLTMR 330 +Y+ D+ ++ E F TL V + T+ E +++ Sbjct: 109 LHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFV 168 Query: 331 EAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFI 390 + + + DLD +A+A+ +G G D A + T Sbjct: 169 HSQELL---SRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWST-- 223 Query: 391 TEYPAEVSPLARRNDV---NPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAK 447 P+E+ D+ NP + D FE G + DA+ + Sbjct: 224 ---PSELGHAGLNGDILVWNPVLEDAFELSSMGIRV--------DADTLKHQL------- 265 Query: 448 AAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDV 495 A DE E + L +P T G GIG R+ ML I V Sbjct: 266 ALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQV 313 >4LNS-A nrPDB Length = 351 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 32/227 (14%), Positives = 66/227 (29%), Gaps = 22/227 (9%) Query: 279 ELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRP 338 + M D + + + + + T ++ P E + A Sbjct: 121 DWEMVMKDDQRNLAFLKEVVCKVYAAIRKTELAVCEKYKQKPILP-ETIQFVHAEHLLLA 179 Query: 339 ETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEA--HLIQPTFITE--YP 394 +L + + +A G G + D A P ++ +P Sbjct: 180 ---YPNLTAKEREREIAREYGAVFLIGIGAVLSSGDRHDARAPDYDDWTSPVEASQVVFP 236 Query: 395 AEVSPLARRNDVNPEITDRFEFFIGG------REIGNGFSELNDAEDQAERFQEQVNAKA 448 P+ N ++ + + E+ + +N + + + Sbjct: 237 RTSKPIPTMNSLSSLKGLNGDILLYNPTLDDSLEVSSMGIRVNAEALRHQI--------S 288 Query: 449 AGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDV 495 D+++ E + L P T G GIG RM+M I +V Sbjct: 289 LTGDDSLLKSEWHQQLLNGEFPQTVGGGIGQSRMVMFMLRKKHIGEV 335 >5LR8-A nrPDB Length = 938 Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 29/177 (16%), Positives = 59/177 (33%), Gaps = 18/177 (10%) Query: 274 EFTMMELYMAYADYH-DLIELT-ESLFRTLAQE--------VLGTTKVTYGEHVFDFGKP 323 E +++ H ++IE E L + + + K D Sbjct: 387 EKWSLDIMQKLLPRHVEIIETIDEELMNNIVSKYGTADISLLKQKLKDMRILDNVDLPAS 446 Query: 324 FEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAH 383 KL ++ K+ R + + L++ A ES + S + +E +A Sbjct: 447 VAKLFIKP--KEKRGKLLVESLESIAEADEKTESQEVENILSETTEKKAESDSEEAPDAE 504 Query: 384 LIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERF 440 P + E+ P A+ + P + + G NG +E++ + + F Sbjct: 505 KEDPEY------ELDPFAKYDPQFPRVVRMANLCVVGGHSVNGVAEIHSEIVKQDVF 555 >1NJ8-A nrPDB Length = 459 Score = 35.9 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 31/185 (16%), Positives = 54/185 (29%), Gaps = 24/185 (12%) Query: 184 FVVRSKILAAIRQFMVARGFMEVETPMMQV----IPGGASARPFITHHNA--------LD 231 F +R IR + G E PM+ + F LD Sbjct: 38 FKIRRYTFEIIRNLLDESGHDEALFPMLIPEDLLAKEAEHIKGFEDEVYWVTHGGKTQLD 97 Query: 232 LDMYLR---IAPELYLKRLVVGGFE----RVFEINRNFRNEGISVR---HNPE-FTMMEL 280 + + LR P Y+ +L V ++++I FR E R E T E Sbjct: 98 VKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQIVNTFRYETKHTRPLIRLREIMTFKEA 157 Query: 281 YMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPET 340 + A++ + + + ++ T + Y F A P+ Sbjct: 158 HTAHSTKEEAENQVKEAIS-IYKKFFDTLGIPYLISKRPEWDKFPGAEYTMAFDTIFPDG 216 Query: 341 DMADL 345 + Sbjct: 217 RTMQI 221 >5E3I-A nrPDB Length = 438 Score = 35.1 bits (79), Expect = 0.065, Method: Composition-based stats. Identities = 34/224 (15%), Positives = 70/224 (31%), Gaps = 21/224 (9%) Query: 189 KILAAIRQFMVARGFMEVETPMMQVI---------PGGASARPFITHHNALDLDMYLRIA 239 ++ + M A G+ ++ P+++ + T + + L + Sbjct: 31 RLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMYTFFDKGNPPESLTLR 90 Query: 240 PE--------LYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLI 291 PE L L+ G RV+ + FR E +F + D+ Sbjct: 91 PEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQKGRYRQFHQFGVETFGVATPDID 150 Query: 292 ELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPET-DMADLDNFDA 350 L L + + V + G+ E+ R A+ + E D D D+ Sbjct: 151 AELIMLTARLWKRMGVDHMVQL--ELNTLGETDERTEYRNALVAFLNEHKDALDEDSQRR 208 Query: 351 AKA-LAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEY 393 + +E + + ++ D + E L + +Y Sbjct: 209 LTTNPLRILDSKIESTQKILENAPKLHDFLKEDSLSHFQQLQDY 252 >3M8U-A nrPDB Length = 522 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 16/47 (34%), Gaps = 4/47 (8%) Query: 239 APELYLKRLVVGGFERVFE----INRNFRNEGISVRHNPEFTMMELY 281 +PE + L GFE FE + R + R E + Sbjct: 329 SPEKAKQLLKEAGFENGFETDIWVQPVVRASNPNPRRMAELVQSDWE 375 >1ADJ-A nrPDB Length = 421 Score = 33.6 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 33/244 (13%), Positives = 78/244 (31%), Gaps = 35/244 (14%) Query: 182 QTFVVRSKILAAIRQFMVARGFMEVETPMMQVI---PGGASARPFITHHNALD----LDM 234 + + +I+A R+ + A G +E+ TP+ + G A I Sbjct: 15 KELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGVGAATDIVRKEMFTFQDRGGR 74 Query: 235 YLRIAPE-------LYLKRLVV--GGFERVFEINRNFRNE-----GISVRHNPEFTMMEL 280 L + PE YL+ + R++ FR E H + + Sbjct: 75 SLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRYRQFHQVNYEALGS 134 Query: 281 YMAYADYHDLIELTESLFRTLAQEVL--------GTTKVTYGEHVFDFGKPFEKLTMREA 332 D ++ L E L + + + Y ++ + P + ++ Sbjct: 135 ENPILDAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAYLREVLSPHREALSEDS 194 Query: 333 IKKYRPETDMADLDNFDAAKALAESIGITV------EKSWGLGRIVTEIFDEVAEAHLIQ 386 ++ + +AL + +G+ E++ + V + ++ + ++ Sbjct: 195 KERLEENPMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVERHLERLSVPYELE 254 Query: 387 PTFI 390 P + Sbjct: 255 PALV 258 >1R6B-X nrPDB Length = 758 Score = 31.7 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 37/95 (38%), Gaps = 2/95 (2%) Query: 146 LTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFME 205 L +L + + + + L L++N +R+ S L A+RQ + F+E Sbjct: 6 LELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQEL--EAFIE 63 Query: 206 VETPMMQVIPGGASARPFITHHNALDLDMYLRIAP 240 TP++ +P ++ L ++ + Sbjct: 64 QTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSS 98 >5ICJ-A nrPDB Length = 221 Score = 31.7 bits (70), Expect = 0.86, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 22/49 (44%) Query: 168 RQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPG 216 R ++++ + ++ R ++ R+ RG+ EV TP + G Sbjct: 17 RGSHMEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAG 65 >2RHQ-A nrPDB Length = 294 Score = 31.7 bits (70), Expect = 0.86, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Query: 254 RVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLG-TTKVT 312 ++ + +R + H+ +FT +E + D + + + +A+++ G ++ Sbjct: 134 KIICPGKVYRRDSDDATHSHQFTQIEGLV--VDKNIKMSDLKGTLELVAKKLFGADREIR 191 Query: 313 YGEHVFDFGKP 323 F F +P Sbjct: 192 LRPSYFPFTEP 202 >2Q1Z-A nrPDB Length = 184 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 46/123 (37%), Gaps = 10/123 (8%) Query: 189 KILAAIRQFMVARGFMEVE---TPMMQVIPGGASARPFITHHNALDLDMYLRIAPELY-L 244 ++ AIR F E+ P ++ + + A D+ + L+ Sbjct: 15 ALMRAIRDHRDEAAFAELFQHFAPKVKGFLMKSGSVASQAEECAQDVMATVWQKAHLFDP 74 Query: 245 KRLVVGGFERVFEINRNFRNEGISVRHNPE----FTMMELYMAYADYHDLIELTESLFRT 300 R V + +F I RN R +G+ PE F + AD +++ + L R Sbjct: 75 SRASVATW--IFTIARNRRIDGLRKDRQPEPEDLFWGPDSEPDQADVYEMQQENARLGRA 132 Query: 301 LAQ 303 +A+ Sbjct: 133 IAR 135 >2ODR-C nrPDB Length = 701 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 38/227 (16%), Positives = 74/227 (32%), Gaps = 44/227 (19%) Query: 280 LYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPE 339 L + ++ DL ++ L TL + +T + + PF+ ++ ++ + E Sbjct: 183 LEDVFPEFKDLTAVSSKL--TLRSHMTSGWFLTVSDLMNKKPLPFKLFSIDRCFRREQKE 240 Query: 340 TDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSP 399 D + L + +A G+ + + + F FI P E Sbjct: 241 -DKSHLMTYHSASCAIAGEGVDINDGKAIAEGLLSQFG------FTNFKFI---PDEKKS 290 Query: 400 LARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDE 459 E Q E + K + A F Sbjct: 291 KY-----------------------------YTPETQTEVYAYHPKLKEW-LEVATFGVY 320 Query: 460 DYVTALEYGL-PPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK 505 V +YG+ P LG+G++R+ M+ N +R+++ +P K Sbjct: 321 SPVALSKYGIDVPVMNLGLGVERLAMISGNFADVREMV-YPQFYEHK 366 >2ALY-A nrPDB Length = 266 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 16/34 (47%), Gaps = 6/34 (17%) Query: 466 EYGLPP-----TA-GLGIGIDRMIMLFTNSHTIR 493 GLPP T G+G++R+ ML IR Sbjct: 216 RLGLPPAYRGVTGFAFGLGVERLAMLRYGIPDIR 249 >4FVM-A nrPDB Length = 910 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 36/194 (18%), Positives = 68/194 (35%), Gaps = 35/194 (18%) Query: 89 QDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRL-LT 147 +DV + + D PE + + + I K +T + I ++ + L+ Sbjct: 735 RDVSIHVLNTILSDKDPEEALQEVYDYLEDIRI--------KVETNNIRIDKYKINMKLS 786 Query: 148 KALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVV--RSKILAAIRQFMVARGFME 205 K + P + +V R R + S TFV+ + +I A Sbjct: 787 KDPKAYP-GGKNMPAVQVALRMRKAGRVVKAGSVITFVITKQDEIDNAA----------- 834 Query: 206 VETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNE 265 +TP + V + + N L D P+ YL++ + ER+ E R + Sbjct: 835 -DTPALSVAERAHALNEVMIKSNNLIPD------PQYYLEKQIFAPVERLLE-----RID 882 Query: 266 GISVRHNPEFTMME 279 +V E ++ Sbjct: 883 SFNVVRLSEALGLD 896 >3H2D-A nrPDB Length = 155 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 17/110 (15%), Positives = 35/110 (31%), Gaps = 16/110 (14%) Query: 103 SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQD 162 L G + GD+ G G + G LSI + +L L + + + Sbjct: 25 ELTPGKPQIKTDNLAKGDVSGLIGMVGPQTKGSLSITFEQKLVLQIMQNMLGENPGKINE 84 Query: 163 QEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGF-MEVETPMM 211 + + + + + + +G+ E+ TPM+ Sbjct: 85 EVTDL---------------VGEITNMVTGGAKNLLGQKGYEFEMATPMV 119 >2W57-A nrPDB Length = 150 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 36/90 (40%), Gaps = 12/90 (13%) Query: 239 APELYLKRLVVG---GFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHD------ 289 A ELY K + +G G V+ + F + GI RH+ E ++ +HD Sbjct: 36 AEELYKKLIDLGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVFELSTQHHHDHLVCLD 95 Query: 290 ---LIELTESLFRTLAQEVLGTTKVTYGEH 316 +IE ++ + +E+ V H Sbjct: 96 CGEVIEFSDDVIEQRQKEIAAKYNVQLTNH 125 >1PYS-A nrPDB Length = 350 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 16/34 (47%), Gaps = 6/34 (17%) Query: 466 EYGLPP-----TA-GLGIGIDRMIMLFTNSHTIR 493 GLPP T G+G++R+ ML IR Sbjct: 300 RLGLPPAYRGVTGFAFGLGVERLAMLRYGIPDIR 333 >5IQL-A nrPDB Length = 133 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 27/96 (28%), Gaps = 2/96 (2%) Query: 138 IHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQF 197 + + ++ + +P DQ Y+ + S FV K+ + Sbjct: 5 LFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFV--KKVWFFLHPS 62 Query: 198 MVARGFMEVETPMMQVIPGGASARPFITHHNALDLD 233 +EV P + G P + D Sbjct: 63 YKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQ 98 >2DU4-A nrPDB Length = 534 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 22/37 (59%), Gaps = 2/37 (5%) Query: 466 EYGLP-PTAGLGIGIDRMIMLFTNSHTIRDVILFPAM 501 EY +P P LG+G++R+ M+ +R ++ +P + Sbjct: 316 EYDIPYPVMNLGLGVERLAMILYGYDDVRKMV-YPQI 351 >2P0R-A nrPDB Length = 333 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 52/159 (32%), Gaps = 16/159 (10%) Query: 32 QGVAFPNDFRRDHTSDQLHEEFD---AKDNQELESLNIEVSVAGRMMTRRIMGKASFVTL 88 Q P D R H+S Q E+ + E + S + + R + FV Sbjct: 4 QAHPVPKDARITHSSGQSFEQMRQECLQRGTLFEDADFPASNSSLFYSERP--QIPFVWK 61 Query: 89 QDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTK 148 + + + + G + +LGD L+++ L + Sbjct: 62 RPGE----IVKNPEFILGGATRTDICQGELGDCWLLAAI------ASLTLNQKALARVIP 111 Query: 149 ALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVR 187 + + G+ + +LD++ +D+ TF R Sbjct: 112 QDQSFGPGYAGIFHFQFWQHSEWLDVVIDDRL-PTFRDR 149 >3J1C-A nrPDB Length = 563 Score = 29.3 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 41/113 (36%), Gaps = 6/113 (5%) Query: 99 VARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGEL-----SIHCTELRLLTKALRPL 153 + + + + L + G + + ++ S+ + + K Sbjct: 209 IDKKKGGTIEDSQLIRGIVLDKEVVHAGMPRRVEKAKIAVLDASLEVEKPEISAKISITS 268 Query: 154 PDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEV 206 PD+ D+E +Y + +D +A+ + + + I + F+ RG + V Sbjct: 269 PDQIKAFLDEEAKYLKDMVDKLASIGA-NVVICQKGIDDIAQHFLAKRGILAV 320 >6NHI-A nrPDB Length = 457 Score = 29.0 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 17/136 (12%), Positives = 41/136 (30%), Gaps = 1/136 (0%) Query: 254 RVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTY 313 + ++I +R + EF + + ++ L+ +E+ + Sbjct: 129 KRYQIQPVWRADRPQKGRFREFYQCDADVVGSESLWQEVELVQLYFKAFKELGVPVAIQM 188 Query: 314 GEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVT 373 G E + E + + D D D + GI+ E L + Sbjct: 189 NNRKILSGLA-EYAGITEQLIDFTVALDKLDKIGKDGVIKEMQEKGISNEAIEKLDFLFH 247 Query: 374 EIFDEVAEAHLIQPTF 389 + + + ++ F Sbjct: 248 QKINALENLQELKTRF 263 >3M7N-A nrPDB Length = 179 Score = 29.0 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 11/96 (11%), Positives = 30/96 (31%), Gaps = 4/96 (4%) Query: 98 YVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKF 157 + +D + + + GD++ R + + + + + R + Sbjct: 37 LIIKDRVAKVESISPIPEIVKGDVVLGRVVDLRNSIALIEVSSKKGENRGPSNRGIGILH 96 Query: 158 HGLQDQ----EVRYRQRYLDLIANDKSRQTFVVRSK 189 D+ E+ YLD++ + +K Sbjct: 97 VSNVDEGYVKEISEAVGYLDILKARVIGDNLRLSTK 132 >6AH0-w nrPDB Length = 501 Score = 28.6 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 37/216 (17%), Positives = 75/216 (34%), Gaps = 20/216 (9%) Query: 168 RQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEV---------ETPMMQVIPGGA 218 ++R +D++A + + +R +I + R + +MEV + ++ A Sbjct: 15 KERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELNA 74 Query: 219 SARPFITHHNALDLDMYLRIAPELYLK---RLVVGGFERVFEINRNFRNEGISVRHNPEF 275 + P L+ E + K + V E+ + N ++ EF Sbjct: 75 ISGPNEFAEFYNR----LKQIKEFHRKHPNEICVPMSVEFEELLKARENPSEEAQNLVEF 130 Query: 276 TMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKK 335 T E Y Y D HD +L + +++ T ++ + +FD K + + ++ Sbjct: 131 TDEEGYGRYLDLHDCYLKYINLKAS--EKLDYITYLSIFDQLFDIPKERKNAEYKRYLEM 188 Query: 336 YRP--ETDMADLDNFDAAKALAESIGITVEKSWGLG 369 + + L I EK W G Sbjct: 189 LLEYLQDYTDRVKPLQDQNELFGKIQAEFEKKWENG 224 >5VM7-A nrPDB Length = 420 Score = 28.2 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 20/54 (37%), Gaps = 1/54 (1%) Query: 202 GFMEVETPMMQVIPGGASARPFITHHNAL-DLDMYLRIAPELYLKRLVVGGFER 254 + E+ T + P+ + ++ L +LY +V GF+R Sbjct: 297 DWKELATAFINPHEVAWELTPYSFVVDWFLNVGDILAQQGQLYHNIDIVDGFDR 350 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.126 0.322 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,175,227 Number of Sequences: 36641 Number of extensions: 663514 Number of successful extensions: 2315 Number of sequences better than 10.0: 68 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 1917 Number of HSP's gapped (non-prelim): 159 length of query: 505 length of database: 10,336,785 effective HSP length: 101 effective length of query: 404 effective length of database: 6,636,044 effective search space: 2680961776 effective search space used: 2680961776 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)