BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P0A6Z3 (624 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IOQ-A nrPDB 1279 0.0 1Y4U-A nrPDB 1146 0.0 2GQ0-A nrPDB 555 e-158 2CG9-A nrPDB 443 e-124 2IOR-A nrPDB 439 e-123 2O1V-A nrPDB 432 e-121 5FWK-A nrPDB 423 e-118 2O1W-A nrPDB 404 e-113 5TTH-B nrPDB 374 e-104 4Z1F-A nrPDB 347 9e-96 2CGE-A nrPDB 273 2e-73 3HJC-A nrPDB 268 4e-72 3Q6N-A nrPDB 261 5e-70 2O1T-A nrPDB 256 2e-68 1HK7-A nrPDB 238 4e-63 1USV-A nrPDB 233 1e-61 1SF8-A nrPDB 232 3e-61 3PRY-A nrPDB 224 8e-59 3Q5K-A nrPDB 207 1e-53 3OMU-A nrPDB 200 1e-51 6B9A-B nrPDB 200 2e-51 5J6L-A nrPDB 198 7e-51 4GQT-A nrPDB 196 3e-50 4XDM-A nrPDB 194 7e-50 5NYI-A nrPDB 193 2e-49 3K60-A nrPDB 192 3e-49 6CJJ-A nrPDB 192 3e-49 5UCI-A nrPDB 190 2e-48 1BGQ-A nrPDB 187 2e-47 4X9L-A nrPDB 186 2e-47 3PEH-A nrPDB 186 4e-47 2XCM-A nrPDB 186 4e-47 1YT0-A nrPDB 183 2e-46 5F5R-A nrPDB 180 2e-45 6D28-A nrPDB 178 7e-45 1Y6Z-A nrPDB 175 5e-44 3IED-A nrPDB 166 2e-41 2AKP-A nrPDB 164 1e-40 3D36-A nrPDB 33 0.53 4WBY-A nrPDB 32 0.64 3EYJ-A nrPDB 32 0.77 2F6S-A nrPDB 32 0.81 4O8A-A nrPDB 30 3.8 >2IOQ-A nrPDB Length = 624 Score = 1279 bits (3309), Expect = 0.0, Method: Compositional matrix adjust. Identities = 624/624 (100%), Positives = 624/624 (100%) Query: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD Sbjct: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 Query: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI Sbjct: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL Sbjct: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE Sbjct: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 Query: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY Sbjct: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 Query: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML Sbjct: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 Query: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV Sbjct: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 Query: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF Sbjct: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 Query: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS Sbjct: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 Query: 541 TDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQA 600 TDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQA Sbjct: 541 TDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQA 600 Query: 601 LLAERGTLEDPNLFIRRMNQLLVS 624 LLAERGTLEDPNLFIRRMNQLLVS Sbjct: 601 LLAERGTLEDPNLFIRRMNQLLVS 624 >1Y4U-A nrPDB Length = 559 Score = 1146 bits (2965), Expect = 0.0, Method: Compositional matrix adjust. Identities = 559/559 (100%), Positives = 559/559 (100%) Query: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD Sbjct: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 Query: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI Sbjct: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL Sbjct: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE Sbjct: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 Query: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY Sbjct: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 Query: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML Sbjct: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 Query: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV Sbjct: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 Query: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF Sbjct: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 Query: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS Sbjct: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 Query: 541 TDADEMSTQMAKLFAAAGQ 559 TDADEMSTQMAKLFAAAGQ Sbjct: 541 TDADEMSTQMAKLFAAAGQ 559 >2GQ0-A nrPDB Length = 303 Score = 555 bits (1430), Expect = e-158, Method: Compositional matrix adjust. Identities = 266/266 (100%), Positives = 266/266 (100%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW Sbjct: 2 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 61 Query: 290 NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR 349 NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR Sbjct: 62 NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR 121 Query: 350 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS 409 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS Sbjct: 122 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS 181 Query: 410 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM 469 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM Sbjct: 182 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM 241 Query: 470 NYLTEFDGKPFQSVSKVDESLEKLAD 495 NYLTEFDGKPFQSVSKVDESLEKLAD Sbjct: 242 NYLTEFDGKPFQSVSKVDESLEKLAD 267 >2CG9-A nrPDB Length = 677 Score = 443 bits (1139), Expect = e-124, Method: Compositional matrix adjust. Identities = 256/681 (37%), Positives = 404/681 (59%), Gaps = 71/681 (10%) Query: 3 GQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGE 62 ET FQ+E+ QL+ L+I+++YSNKEIFLRELISNASDA DK+R+++LS+P E + + Sbjct: 2 ASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPD 61 Query: 63 LRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQ 122 L +R++ +++ L I D+G+GMT+ E+I++LGTIAKSGTK+F+E+L + D +IGQ Sbjct: 62 LFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSA--GADVSMIGQ 119 Query: 123 FGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLH 179 FGVGFYS F+VAD+V V +++ ++ WES G +TV D E RGT + L Sbjct: 120 FGVGFYSLFLVADRVQVISKSNDDE---QYIWESNAGGSFTVTLDEVNERIGRGTILRLF 176 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVIS---------------- 223 L++ + E+L++ R++ +I ++S+ +A P+++ +E + E I Sbjct: 177 LKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKD 236 Query: 224 ------------------------------WEKINKAQALWTRNKSEITDEEYKEFYKHI 253 E++NK + LWTRN S+IT EEY FYK I Sbjct: 237 EDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSI 296 Query: 254 AHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW-NRDHKHGLKLYVQRVFIMDDAEQ 312 ++D+ DPL H VEG+ E+ ++L+IP +AP+D++ ++ K+ +KLYV+RVFI D+AE Sbjct: 297 SNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAED 356 Query: 313 FMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQ 372 +P +L FV+G++DS DLPLN+SRE+LQ + + + +R + K++++ ++A +D+E+++ Sbjct: 357 LIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIA-EDSEQFE 415 Query: 373 TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYY 432 F+ F +K G ED N+ A+AKLLR+ ST S + SL DYV+RM E Q+ IYY Sbjct: 416 KFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK--SVDELTSLTDYVTRMPEHQKNIYY 473 Query: 433 ITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEK 492 IT +S A + SP L+ L+ K EVL L+D IDE+ L EF+GK ++K D LE+ Sbjct: 474 ITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITK-DFELEE 532 Query: 493 LADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAK 552 +E E KE K P +K +LG++V+ V ++++L D PA + T S M + Sbjct: 533 TDEEKAEREKEI-KEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMER 591 Query: 553 LFAAAGQK------VPEVKYIFELNPDHVLVKRAADTEDEA-----KFSEWVELLLDQAL 601 + A + K FE++P ++K DE + +LL + AL Sbjct: 592 IMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETAL 651 Query: 602 LAERGTLEDPNLFIRRMNQLL 622 L +L++P F R+N+L+ Sbjct: 652 LTSGFSLDEPTSFASRINRLI 672 >2IOR-A nrPDB Length = 235 Score = 439 bits (1130), Expect = e-123, Method: Compositional matrix adjust. Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD Sbjct: 21 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 80 Query: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI Sbjct: 81 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 140 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL Sbjct: 141 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 200 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREE 215 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREE Sbjct: 201 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREE 235 >2O1V-A nrPDB Length = 666 Score = 432 bits (1112), Expect = e-121, Method: Compositional matrix adjust. Identities = 253/642 (39%), Positives = 379/642 (59%), Gaps = 33/642 (5%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 23 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELT 82 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLG---SDQAKDSQLIG 121 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LIG Sbjct: 83 VKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIG 142 Query: 122 QFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLH 179 QFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 143 QFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITLV 199 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEI-EKREEKDGETVISWEKINKAQALWTRNK 238 L+E ++L+ +++++ KYS I P+ + + G+TV WE +N + +W R Sbjct: 200 LKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTGGGGKTVWDWELMNDIKPIWQRPS 259 Query: 239 SEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP---WDMWNRDHKH 295 E+ D+EYK FYK + + +DP+ + H EG+ + S+L++P+ AP +D + Sbjct: 260 KEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSD 319 Query: 296 GLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKR 355 +KLYV+RVFI DD MP YL FV+G++DS DLPLNVSRE LQ + + +R L ++ Sbjct: 320 YIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRK 379 Query: 356 VLQMLEKLAKDDAEKYQ-TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTV 414 L M++K+A EKY TFW++FG +K G ED +N+ +AKLLRF S+H S Sbjct: 380 TLDMIKKIAD---EKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPS--DIT 434 Query: 415 SLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTE 474 SL+ YV RMKE Q+KIY++ S A+SSP +E L KKG EV+ L++ +DE+ + L E Sbjct: 435 SLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPE 494 Query: 475 FDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVK-ALLGERVKDVRLTHRLT 533 FDGK FQ+V+K ++ +++ ES + EK P ++ +K L ++++ ++ RLT Sbjct: 495 FDGKRFQNVAKEGVKFDE-SEKTKESREAIEKEFEPLLNWMKDKALKDKIEKAVVSQRLT 553 Query: 534 DTPAIVSTDADEMSTQMAKLFAA----AGQKVPEVKY-----IFELNPDHVLVK----RA 580 ++P + S M ++ A G+ + Y FE+NP H L+K R Sbjct: 554 ESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRV 613 Query: 581 ADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 + ED+ S+ +L + A L L D + R+ ++L Sbjct: 614 KEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERML 655 >5FWK-A nrPDB Length = 727 Score = 423 bits (1087), Expect = e-118, Method: Compositional matrix adjust. Identities = 252/682 (36%), Positives = 393/682 (57%), Gaps = 76/682 (11%) Query: 6 TRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRV 65 T FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL++ Sbjct: 17 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKI 76 Query: 66 RVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGV 125 + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFGV Sbjct: 77 DIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFGV 134 Query: 126 GFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLREG 183 GFYSA++VA+KV V T+ + WES+ G +TV E RGT++ LHL+E Sbjct: 135 GFYSAYLVAEKVVVITK---HNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKED 191 Query: 184 EDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGET----------------------- 220 + E+L++ RV+ ++ K+S I P+ + +E++ E Sbjct: 192 QTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKP 251 Query: 221 ---------------------------VISWEKINKAQALWTRNKSEITDEEYKEFYKHI 253 I E++NK + +WTRN +IT EEY EFYK + Sbjct: 252 KIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSL 311 Query: 254 AHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLK-LYVQRVFIMDDAEQ 312 +D+ D L H VEG+ E+ +LL+IP +AP+D++ K LYV+RVFIMD ++ Sbjct: 312 TNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDE 371 Query: 313 FMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQ 372 +P YL F+RG++DS DLPLN+SRE+LQ S + + +R + K+ L++ +LA +D E Y+ Sbjct: 372 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA-EDKENYK 430 Query: 373 TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSA-QTVSLEDYVSRMKEGQEKIY 431 F++ F LK G ED N+ +++LLR+ HT S + SL +YVSRMKE Q+ IY Sbjct: 431 KFYEAFSKNLKLGIHEDSTNRRRLSELLRY---HTSQSGDEMTSLSEYVSRMKETQKSIY 487 Query: 432 YITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLE 491 YIT +S +S +E +RK+G EV+ +++ IDE+ + L EFDGK SV+K Sbjct: 488 YITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKE-GLEL 546 Query: 492 KLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMA 551 +E + +E++ +K +L ++V+ V +++RL +P + T + M Sbjct: 547 PEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANME 606 Query: 552 KLFAA-AGQKVPEVKYI-----FELNPDHVLV-----KRAADTEDEAKFSEWVELLLDQA 600 ++ A A + + Y+ E+NPDH +V K AD D+A + V LL + A Sbjct: 607 RIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKA-VKDLVVLLFETA 665 Query: 601 LLAERGTLEDPNLFIRRMNQLL 622 LL+ +LEDP R+ +++ Sbjct: 666 LLSSGFSLEDPQTHSNRIYRMI 687 >2O1W-A nrPDB Length = 506 Score = 404 bits (1037), Expect = e-113, Method: Compositional matrix adjust. Identities = 219/491 (44%), Positives = 312/491 (63%), Gaps = 18/491 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 23 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELT 82 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLG---SDQAKDSQLIG 121 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LIG Sbjct: 83 VKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIG 142 Query: 122 QFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLH 179 QFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 143 QFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITLV 199 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEI-EKREEKDGETVISWEKINKAQALWTRNK 238 L+E ++L+ +++++ KYS I P+ + + G+TV WE +N + +W R Sbjct: 200 LKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTGGGGKTVWDWELMNDIKPIWQRPS 259 Query: 239 SEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP---WDMWNRDHKH 295 E+ D+EYK FYK + + +DP+ + H EG+ + S+L++P+ AP +D + Sbjct: 260 KEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSD 319 Query: 296 GLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKR 355 +KLYV+RVFI DD MP YL FV+G++DS DLPLNVSRE LQ + + +R L ++ Sbjct: 320 YIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRK 379 Query: 356 VLQMLEKLAKDDAEKYQ-TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTV 414 L M++K+A EKY TFW++FG +K G ED +N+ +AKLLRF S+H S Sbjct: 380 TLDMIKKIAD---EKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPS--DIT 434 Query: 415 SLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTE 474 SL+ YV RMKE Q+KIY++ S A+SSP +E L KKG EV+ L++ +DE+ + L E Sbjct: 435 SLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPE 494 Query: 475 FDGKPFQSVSK 485 FDGK FQ+V+K Sbjct: 495 FDGKRFQNVAK 505 >5TTH-B nrPDB Length = 672 Score = 374 bits (960), Expect = e-104, Method: Compositional matrix adjust. Identities = 226/632 (35%), Positives = 371/632 (58%), Gaps = 40/632 (6%) Query: 9 FQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD-GELRVRV 67 FQ+E K+LL ++ SLYS KE+F+RELISN SDA +KLR R ++ GD + + + Sbjct: 39 FQAETKKLLDIVARSLYSEKEVFIRELISNGSDALEKLRHRMITAG----GDTAPMEIHL 94 Query: 68 SFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGF 127 D K T TI D GVGM +++++ +LGTIA+SG+K+FL++L + S +IGQFGVGF Sbjct: 95 QTDSVKGTFTIQDTGVGMNKEDLVSNLGTIARSGSKAFLDALQNQAEASSSIIGQFGVGF 154 Query: 128 YSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHLREGEDEF 187 YSAF+VADKV V +++A E G W S G G + VA+ + +GT+I LHL++ EF Sbjct: 155 YSAFMVADKVEVYSQSA-EADAPGYKWSSDGSGVFEVAEASGVRQGTKIVLHLKDDCKEF 213 Query: 188 LDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEITDEEYK 247 + RV+ +++KYS+ ++ P+ + R ++N QALW +I++ +++ Sbjct: 214 SSEDRVKEVVTKYSNFVSFPIFLNGR------------RLNTLQALWMMEPKDISEWQHE 261 Query: 248 EFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP--WDMWNRDHKHGLKLYVQRVF 305 EFY+++A ++ P H R + S+ Y+P P +D+ +R+ + LY +++ Sbjct: 262 EFYRYVAQAYDKPRYTLHYRADAPLNIRSIFYVPEMKPSMFDV-SREMGSSVALYSRKIL 320 Query: 306 IMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAK 365 I A +P +LRF+RG++DS D+PLN+S E+LQ+S + R LR+ L +RV++ L +K Sbjct: 321 IQTKATDILPKWLRFLRGVVDSEDIPLNLSAELLQESALIRKLRDVLQQRVIRFLLDQSK 380 Query: 366 DDAEKYQTFWQQFGLVLKEG--PAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRM 423 D EKY F++ +GL ++EG + + +E IAKLLRF S+ + QT SL +Y SRM Sbjct: 381 KDPEKYARFFEDYGLFMREGIVTTGEQSVKEDIAKLLRFESSALPAGQQT-SLMEYSSRM 439 Query: 424 KEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSV 483 K G IYY+ A + A+ SP+ E +++K +EVL ++ DE + +L EFD K S Sbjct: 440 KAGTRNIYYLCAPNRHLAEHSPYFEAMKQKDMEVLFCFEQFDELTLLHLREFDRKKLIS- 498 Query: 484 SKVDESLEKLADEVDESAKEAEKALTP-----FIDRVKALLGERVKDVRLTHRLTDTPAI 538 ++ D ++ +E + +K A + L+ + ++ L +RV ++++T RL PA+ Sbjct: 499 AETDIVVDHYKEEKFQDSKPASERLSSEQAEDLLAWMRNALVQRVTNIKVTPRLDTHPAM 558 Query: 539 VST---DADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVEL 595 ++ A + +L ++ ++ ++ E+N H L+K+ +D E +L Sbjct: 559 ITVLEMGAARHFLRTQQLARSSEERAQILQPTLEINTGHDLIKKLHALKDSN--PELAQL 616 Query: 596 LLDQ----ALLAERGTLEDPNLFIRRMNQLLV 623 LL+Q A++A G EDP I R+NQLL Sbjct: 617 LLEQIYDNAMIAA-GLNEDPRPMISRLNQLLT 647 >4Z1F-A nrPDB Length = 502 Score = 347 bits (890), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 186/480 (38%), Positives = 300/480 (62%), Gaps = 24/480 (5%) Query: 9 FQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVS 68 FQ+E K+LL ++ SLYS KE+F+RELISNASDA +KLR + +S+ + E+ + + Sbjct: 31 FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDG---QALPEMEIHLQ 87 Query: 69 FDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFY 128 + +K T+TI D G+GMT++E++ +LGTIA+SG+K+FL++L + S++IGQFGVGFY Sbjct: 88 TNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFY 147 Query: 129 SAFIVADKVTVRTRAAGEKPEN-GVFWESAGEGEYTVADITKEDRGTEITLHLREGEDEF 187 SAF+VAD+V V +R+A P + G W S G G + +A+ + GT+I +HL+ EF Sbjct: 148 SAFMVADRVEVYSRSAA--PGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEF 205 Query: 188 LDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEITDEEYK 247 + RVR +++KYS+ ++ P+ + R ++N QA+W + ++ + +++ Sbjct: 206 SSEARVRDVVTKYSNFVSFPLYLNGR------------RMNTLQAIWMMDPKDVREWQHE 253 Query: 248 EFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP--WDMWNRDHKHGLKLYVQRVF 305 EFY+++A + P H + + S+ Y+P P +D+ +R+ + LY ++V Sbjct: 254 EFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDV-SRELGSSVALYSRKVL 312 Query: 306 IMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAK 365 I A +P +LRF+RG++DS D+PLN+SRE+LQ+S + R LR+ L +R+++ +K Sbjct: 313 IQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSK 372 Query: 366 DDAEKYQTFWQQFGLVLKEG--PAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRM 423 DAEKY F++ +GL ++EG A + +E IAKLLR+ S+ S Q SL +Y SRM Sbjct: 373 KDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSAL-PSGQLTSLSEYASRM 431 Query: 424 KEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSV 483 + G IYY+ A + A+ SP+ E ++KK EVL ++ DE + +L EFD K SV Sbjct: 432 RAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISV 491 >2CGE-A nrPDB Length = 405 Score = 273 bits (697), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 155/405 (38%), Positives = 243/405 (60%), Gaps = 17/405 (4%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 + LWTRN S+IT EEY FYK I++D+ DPL H VEG+ E+ ++L+IP +AP+D++ Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 290 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 348 ++ K+ +KLYV+RVFI D+AE +P +L FV+G++DS DLPLN+SRE+LQ + + + + Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 349 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 408 R + K++++ ++A +D+E+++ F+ F +K G ED N+ A+AKLLR+ ST Sbjct: 121 RKNIVKKLIEAFNEIA-EDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK-- 177 Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 468 S + SL DYV+RM E Q+ IYYIT +S A + SP L+ L+ K EVL L+D IDE+ Sbjct: 178 SVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYA 237 Query: 469 MNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRL 528 L EF+GK ++K D LE+ +E E KE K P +K +LG++V+ V + Sbjct: 238 FTQLKEFEGKTLVDITK-DFELEETDEEKAEREKEI-KEYEPLTKALKEILGDQVEKVVV 295 Query: 529 THRLTDTPAIVSTDADEMSTQMAKLFAAAGQK------VPEVKYIFELNPDHVLVKRAAD 582 +++L D PA + T S M ++ A + K FE++P ++K Sbjct: 296 SYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKK 355 Query: 583 TEDEA-----KFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 DE + +LL + ALL +L++P F R+N+L+ Sbjct: 356 RVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLI 400 >3HJC-A nrPDB Length = 444 Score = 268 bits (686), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 148/403 (36%), Positives = 246/403 (61%), Gaps = 15/403 (3%) Query: 231 QALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWN 290 + LWTR+ ++T EEY FYK I++D+ DP H VEG+ E+ S++++P +AP+DM+ Sbjct: 20 KPLWTRDPKDVTKEEYAAFYKAISNDWEDPAATKHFSVEGQLEFRSIMFVPKRAPFDMFE 79 Query: 291 RDHK-HGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR 349 + K + +KLYV+RVFIMD+ E P++L FV+G++DS DLPLN+SRE LQ + + + +R Sbjct: 80 PNKKRNNIKLYVRRVFIMDNCEDLCPDWLGFVKGVVDSEDLPLNISRENLQQNKILKVIR 139 Query: 350 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS 409 + K+ L+M +++A ++ E Y+ F++QFG +K G ED AN++ + +LLRF ST +S Sbjct: 140 KNIVKKCLEMFDEVA-ENKEDYKQFYEQFGKNIKLGIHEDTANRKKLMELLRFYST--ES 196 Query: 410 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM 469 + +L+DYV+RMK GQ+ IYYIT DS ++SP +E R++G+EVL +++ IDE++M Sbjct: 197 GEEMTTLKDYVTRMKAGQKSIYYITGDSKKKLETSPFIEQARRRGLEVLFMTEPIDEYVM 256 Query: 470 NYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLT 529 + +F+ K F ++K E+ E + +E + A +K +LG++V+ V ++ Sbjct: 257 QQVKDFEDKKFACLTKEGVHFEESE-EEKQQREEEKAACEKLCKTMKEVLGDKVEKVIVS 315 Query: 530 HRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEV------KYIFELNPDHVLVK----R 579 RL+ +P I+ T S M ++ + + K ELNP H ++K R Sbjct: 316 ERLSTSPCILVTSEFGWSAHMEQIMRNQALRDSSMAQYMMSKKTMELNPRHPIIKELRRR 375 Query: 580 AADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 E++ + V LL D +LL LEDP + R+N+++ Sbjct: 376 VGADENDKAVKDLVFLLFDTSLLTSGFQLEDPTGYAERINRMI 418 >3Q6N-A nrPDB Length = 448 Score = 261 bits (668), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 149/405 (36%), Positives = 244/405 (60%), Gaps = 17/405 (4%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 + +WTRN +IT+EEY EFYK + +D+ D L H VEG+ E+ +LL++P +AP+D++ Sbjct: 3 TKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLF 62 Query: 290 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 348 NR K+ +KLYV+RVFIMD+ E+ +P YL F+RG++DS DLPLN+SRE+LQ S + + + Sbjct: 63 ENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 122 Query: 349 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 408 R L K+ L++ +LA +D E Y+ F++QF +K G ED N++ +++LLR+ ++ Sbjct: 123 RKNLVKKCLELFTELA-EDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSA-- 179 Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 468 S + VSL+DY +RMKE Q+ IYYIT ++ +S +E LRK G+EV+ + + IDE+ Sbjct: 180 SGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYC 239 Query: 469 MNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRL 528 + L EF+GK SV+K L + +E + ++ K +K +L ++V+ V + Sbjct: 240 VQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFEN-LCKIMKDILEKKVEKVVV 298 Query: 529 THRLTDTPAIVSTDADEMSTQMAKLFAAAGQK------VPEVKYIFELNPDHVLV----- 577 ++RL +P + T + M ++ A + K E+NPDH ++ Sbjct: 299 SNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQ 358 Query: 578 KRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 K AD D++ + V LL + ALL+ +LEDP R+ +++ Sbjct: 359 KAEADKNDKS-VKDLVILLYETALLSSGFSLEDPQTHANRIYRMI 402 >2O1T-A nrPDB Length = 450 Score = 256 bits (654), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 151/414 (36%), Positives = 236/414 (57%), Gaps = 24/414 (5%) Query: 227 INKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP- 285 +N + +W R E+ D+EYK FYK + + +DP+ + H EG+ + S+L++P+ AP Sbjct: 21 MNDIKPIWQRPSKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 80 Query: 286 --WDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDST 343 +D + +KLYV+RVFI DD MP YL FV+G++DS DLPLNVSRE LQ Sbjct: 81 GLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHK 140 Query: 344 VTRNLRNALTKRVLQMLEKLAKDDAEKYQ-TFWQQFGLVLKEGPAEDFANQEAIAKLLRF 402 + + +R L ++ L M++K+A EKY TFW++FG +K G ED +N+ +AKLLRF Sbjct: 141 LLKVIRKKLVRKTLDMIKKIAD---EKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRF 197 Query: 403 ASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSD 462 S+H S SL+ YV RMKE Q+KIY++ S A+SSP +E L KKG EV+ L++ Sbjct: 198 QSSHHPSD--ITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTE 255 Query: 463 RIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVK-ALLGE 521 +DE+ + L EFDGK FQ+V+K ++ +++ ES + EK P ++ +K L + Sbjct: 256 PVDEYCIQALPEFDGKRFQNVAKEGVKFDE-SEKTKESREAIEKEFEPLLNWMKDKALKD 314 Query: 522 RVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAA----AGQKVPEVKY-----IFELNP 572 +++ ++ RLT++P + S M ++ A G+ + Y FE+NP Sbjct: 315 KIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP 374 Query: 573 DHVLVK----RAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 H L+K R + ED+ S+ +L + A L L D + R+ ++L Sbjct: 375 RHPLIKDMLRRVKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERML 428 >1HK7-A nrPDB Length = 288 Score = 238 bits (608), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 127/293 (43%), Positives = 192/293 (65%), Gaps = 6/293 (2%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 + LWTRN S+IT EEY FYK I++D+ DPL H VEG+ E+ ++L+IP +AP+D++ Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 290 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 348 ++ K+ +KLYV+RVFI D+AE +P +L FV+G++DS DLPLN+SRE+LQ + + + + Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 349 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 408 R + K++++ ++A +D+E+++ F+ F +K G ED N+ A+AKLLR+ ST Sbjct: 121 RKNIVKKLIEAFNEIA-EDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK-- 177 Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 468 S + SL DYV+RM E Q+ IYYIT +S A + SP L+ L+ K EVL L+D IDE+ Sbjct: 178 SVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYA 237 Query: 469 MNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGE 521 L EF+GK ++K D LE+ +E E KE K P +K +LG+ Sbjct: 238 FTQLKEFEGKTLVDITK-DFELEETDEEKAEREKEI-KEYEPLTKALKEILGD 288 >1USV-A nrPDB Length = 260 Score = 233 bits (595), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 116/258 (44%), Positives = 176/258 (68%), Gaps = 4/258 (1%) Query: 229 KAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDM 288 K + LWTRN S+IT EEY FYK I++D+ DPL H VEG+ E+ ++L+IP +AP+D+ Sbjct: 2 KTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDL 61 Query: 289 W-NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRN 347 + ++ K+ +KLYV+RVFI D+AE +P +L FV+G++DS DLPLN+SRE+LQ + + + Sbjct: 62 FESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKV 121 Query: 348 LRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHT 407 +R + K++++ ++A +D+E+++ F+ F +K G ED N+ A+AKLLR+ ST Sbjct: 122 IRKNIVKKLIEAFNEIA-EDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK- 179 Query: 408 DSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEW 467 S + SL DYV+RM E Q+ IYYIT +S A + SP L+ L+ K EVL L+D IDE+ Sbjct: 180 -SVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEY 238 Query: 468 MMNYLTEFDGKPFQSVSK 485 L EF+GK ++K Sbjct: 239 AFTQLKEFEGKTLVDITK 256 >1SF8-A nrPDB Length = 126 Score = 232 bits (592), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 114/114 (100%), Positives = 114/114 (100%) Query: 511 FIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFEL 570 FIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFEL Sbjct: 13 FIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFEL 72 Query: 571 NPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS 624 NPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS Sbjct: 73 NPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS 126 >3PRY-A nrPDB Length = 268 Score = 224 bits (571), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 115/259 (44%), Positives = 170/259 (65%), Gaps = 6/259 (2%) Query: 229 KAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDM 288 K + +WTRN +IT EEY EFYK + +D+ D L H VEG+ E+ +LL+IP +AP+D+ Sbjct: 2 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 61 Query: 289 WNRDHKHGLK-LYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRN 347 + K LYV+RVFIMD ++ +P YL F+RG++DS DLPLN+SRE+LQ S + + Sbjct: 62 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 121 Query: 348 LRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHT 407 +R + K+ L++ +LA +D E Y+ F++ F LK G ED N+ +++LLR+ HT Sbjct: 122 IRKNIVKKCLELFSELA-EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRY---HT 177 Query: 408 DSSA-QTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDE 466 S + SL +YVSRMKE Q+ IYYIT +S +S +E +RK+G EV+ +++ IDE Sbjct: 178 SQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDE 237 Query: 467 WMMNYLTEFDGKPFQSVSK 485 + + L EFDGK SV+K Sbjct: 238 YCVQQLKEFDGKSLVSVTK 256 >3Q5K-A nrPDB Length = 231 Score = 207 bits (527), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 103/216 (47%), Positives = 154/216 (71%), Gaps = 9/216 (4%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+++L++P + L Sbjct: 21 ETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKIRYQSLTDPSVLGESPRLC 80 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +RV DK+ +TLT+ DNG+GMT+ +++++LGTIA+SGTK+F+E+L + D +IGQFG Sbjct: 81 IRVVPDKENKTLTVEDNGIGMTKADLVNNLGTIARSGTKAFMEAL--EAGGDMSMIGQFG 138 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLRE 182 VGFYSA++VAD+VTV ++ + WES+ G +T+ + D RGT ITLHL+E Sbjct: 139 VGFYSAYLVADRVTVTSK---NNSDESYVWESSAGGTFTITSTPESDMKRGTRITLHLKE 195 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVE--IEKREEK 216 + E+L+ R++ +I K+S+ I +E +EK EK Sbjct: 196 DQMEYLEPRRLKELIKKHSEFIGYDIELMVEKTTEK 231 >3OMU-A nrPDB Length = 231 Score = 200 bits (509), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 98/208 (47%), Positives = 150/208 (72%), Gaps = 7/208 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISN+SDA DK+R+++L+N + + LR Sbjct: 21 ETFAFQAEINQLMSLIINTFYSNKEIFLRELISNSSDACDKIRYQSLTNQSVLGDEPHLR 80 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +RV D+ +TLT+ D+G+GMT+ +++++LGTIA+SGTKSF+E+L + D +IGQFG Sbjct: 81 IRVIPDRVNKTLTVEDSGIGMTKADLVNNLGTIARSGTKSFMEAL--EAGGDMSMIGQFG 138 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLRE 182 VGFYSA++VAD+VTV ++ ++ WES+ G +TV D RGT I LHL+E Sbjct: 139 VGFYSAYLVADRVTVVSK---NNEDDAYTWESSAGGTFTVTSTPDCDLKRGTRIVLHLKE 195 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEI 210 + E+L++ R++ +I K+S+ I +E+ Sbjct: 196 DQQEYLEERRLKDLIKKHSEFIGYDIEL 223 >6B9A-B nrPDB Length = 256 Score = 200 bits (508), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 103/217 (47%), Positives = 152/217 (70%), Gaps = 7/217 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISN+SDA DK+R+ +L++P + EL Sbjct: 38 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELH 97 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + +K RTLTI D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 98 INLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFG 155 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 VGFYSA++VA+KVTV T+ + WES+ G +TV T E RGT++ LHL+E Sbjct: 156 VGFYSAYLVAEKVTVITK---HNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKE 212 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGE 219 + E+L++ R++ I+ K+S I P+ + +E+D E Sbjct: 213 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKE 249 >5J6L-A nrPDB Length = 228 Score = 198 bits (503), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 102/217 (47%), Positives = 151/217 (69%), Gaps = 7/217 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISN+SDA DK+R+ +L++P + EL Sbjct: 10 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELH 69 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + +K RTLTI D G+GMT+ ++I++ GTIAKSGTK+F+E+L + D +IGQFG Sbjct: 70 INLIPNKQDRTLTIVDTGIGMTKADLINNAGTIAKSGTKAFMEALQA--GADISMIGQFG 127 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 VGFYSA++VA+KVTV T+ + WES+ G +TV T E RGT++ LHL+E Sbjct: 128 VGFYSAYLVAEKVTVITK---HNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKE 184 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGE 219 + E+L++ R++ I+ K+S I P+ + +E+D E Sbjct: 185 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKE 221 >4GQT-A nrPDB Length = 227 Score = 196 bits (498), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 94/208 (45%), Positives = 150/208 (72%), Gaps = 7/208 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ YSNKEI+LRELISNASDA DK+R++AL+ P + EL Sbjct: 9 ETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELF 68 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 ++++ +K+++TLTI D G+GMT+ +++++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 69 IKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQA--GADISMIGQFG 126 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLRE 182 VGFYSAF+VADKV V ++ ++ WES+ G + V + RGT+I +H++E Sbjct: 127 VGFYSAFLVADKVVVTSK---NNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKE 183 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEI 210 + +FL++ +++ I+ K+S I P+++ Sbjct: 184 DQIDFLEERKIKEIVKKHSQFIGYPIKL 211 >4XDM-A nrPDB Length = 259 Score = 194 bits (494), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 96/211 (45%), Positives = 154/211 (72%), Gaps = 6/211 (2%) Query: 9 FQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVS 68 FQ+E+ QL+ L+I++ YSNKE+FLRELISNASDA DK+R+++L++ + E EL +++ Sbjct: 47 FQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKII 106 Query: 69 FDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFY 128 DK +TLT+ D+G+GMT+ +++ +LGTIA+SGTK+F+E L S A D +IGQFGVGFY Sbjct: 107 PDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSG-AADISMIGQFGVGFY 165 Query: 129 SAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE-DRGTEITLHLREGEDE 186 SA++VAD V V ++ + WES+ GE+T+A D T+ RGT+I LH++E + + Sbjct: 166 SAYLVADTVIVHSK---NNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLD 222 Query: 187 FLDDWRVRSIISKYSDHIALPVEIEKREEKD 217 +LD+ ++++++ K+S+ I P+ + +EK+ Sbjct: 223 YLDETKIKNLVKKHSEFIQYPISLLTIKEKE 253 >5NYI-A nrPDB Length = 229 Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 97/217 (44%), Positives = 149/217 (68%), Gaps = 7/217 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ Y+NKEIFLRELI+N +DA DK+R+ L++P + EL Sbjct: 11 ETFAFQAEIAQLMTLIINTFYTNKEIFLRELITNTTDALDKIRYETLTDPTKLDTGKELH 70 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + +K RTLTI D G+GMT+ ++I++LGTIAK+GTK+F+E+L + D +IGQFG Sbjct: 71 INLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKTGTKAFMEALQA--GADITMIGQFG 128 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 VGFY+A++VA+KVTV T+ + WE+ G +TV T E RGT++ LHL+E Sbjct: 129 VGFYTAYLVAEKVTVITK---HNDDEQYAWETTAGGTFTVRTDTGEPMGRGTKVILHLKE 185 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGE 219 + E+L++ R++ I+ K++ I P+ + EE+D E Sbjct: 186 DQTEYLEERRIKEIVKKHTQFIGYPITLFVEEERDKE 222 >3K60-A nrPDB Length = 223 Score = 192 bits (489), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 100/227 (44%), Positives = 158/227 (69%), Gaps = 10/227 (4%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET F ++++QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ ++++ + E Sbjct: 4 ETFAFNADIRQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESITDTQKLSAEPEFF 63 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +R+ DK TLTI D+G+GMT++++I++LGTIA+SGTK+F+E++ + + D +IGQFG Sbjct: 64 IRIIPDKTNNTLTIEDSGIGMTKNDLINNLGTIARSGTKAFMEAIQA--SGDISMIGQFG 121 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLHLR 181 VGFYSA++VAD V V ++ + WESA G +TV D T E RGT+I LHL+ Sbjct: 122 VGFYSAYLVADHVVVISK---NNDDEQYVWESAAGGSFTVTKDETNEKLGRGTKIILHLK 178 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKIN 228 E + E+L++ R++ ++ K+S+ I+ P+++ E+ G WE++N Sbjct: 179 EDQLEYLEEKRIKDLVKKHSEFISFPIKL--YCERGGGVEHEWEELN 223 >6CJJ-A nrPDB Length = 230 Score = 192 bits (489), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 99/209 (47%), Positives = 149/209 (71%), Gaps = 8/209 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET F +E+ QL+ L+I+++YSNKEIFLRELISNASDA DK+R++ALS+P E + EL Sbjct: 19 ETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELF 78 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +R+ KD++ L I D+G+GMT+ +++++LGTIAKSGTKSF+E+L + D +IGQFG Sbjct: 79 IRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSA--GADVSMIGQFG 136 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLHLR 181 VGFYS F+VAD V V ++ + WES G++TV D T E RGT + L L+ Sbjct: 137 VGFYSLFLVADHVQVISK---HNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLK 193 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEI 210 E + E+L++ R++ ++ K+S+ +A P+++ Sbjct: 194 EDQLEYLEEKRIKEVVKKHSEFVAYPIQL 222 >5UCI-A nrPDB Length = 220 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 96/207 (46%), Positives = 144/207 (69%), Gaps = 7/207 (3%) Query: 6 TRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRV 65 T FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL++ Sbjct: 16 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKI 75 Query: 66 RVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGV 125 + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L D +IGQFGV Sbjct: 76 DIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEAL--QAGADISMIGQFGV 133 Query: 126 GFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLREG 183 GFYSA++VA+KV V T+ + WES+ G +TV E RGT++ LHL+E Sbjct: 134 GFYSAYLVAEKVVVITK---HNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKED 190 Query: 184 EDEFLDDWRVRSIISKYSDHIALPVEI 210 + E+L++ RV+ ++ K+S I P+ + Sbjct: 191 QTEYLEERRVKEVVKKHSQFIGYPITL 217 >1BGQ-A nrPDB Length = 225 Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 95/209 (45%), Positives = 151/209 (72%), Gaps = 8/209 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I+++YSNKEIFLRELISNASDA DK+R+++LS+P E + +L Sbjct: 15 ETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLF 74 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +R++ +++ L I D+G+GMT+ E+I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 75 IRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSA--GADVSMIGQFG 132 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLHLR 181 VGFYS F+VAD+V V +++ ++ WES G +TV D E RGT + L L+ Sbjct: 133 VGFYSLFLVADRVQVISKSNDDEQ---YIWESNAGGSFTVTLDEVNERIGRGTILRLFLK 189 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEI 210 + + E+L++ R++ +I ++S+ +A P+++ Sbjct: 190 DDQLEYLEEKRIKEVIKRHSEFVAYPIQL 218 >4X9L-A nrPDB Length = 250 Score = 186 bits (472), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 96/209 (45%), Positives = 147/209 (70%), Gaps = 8/209 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QLL L+I++ YSNKEIFLRELISN+SDA DK+RF +L++ + EL Sbjct: 40 ETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPELF 99 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + DK TL+I D+GVGMT+ +++++LGTIA+SGTK F+E+L + D +IGQFG Sbjct: 100 IHIVPDKASNTLSIIDSGVGMTKSDLVNNLGTIARSGTKEFMEALAA--GADVSMIGQFG 157 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKED--RGTEITLHLR 181 VGFYSA++VA++V V T+ + WES G +TV D + E RGT+ITL+L+ Sbjct: 158 VGFYSAYLVAERVVVTTK---HNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKITLYLK 214 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEI 210 + + E+L++ R++ ++ K+S+ I+ P+ + Sbjct: 215 DDQLEYLEERRLKDLVKKHSEFISYPISL 243 >3PEH-A nrPDB Length = 281 Score = 186 bits (471), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 94/207 (45%), Positives = 144/207 (69%), Gaps = 7/207 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E+ +Q+EV +L+ ++++SLY+ KE+FLRELISNA+DA +K+RF +LS+ + + +L Sbjct: 24 ESHQYQTEVTRLMDIIVNSLYTQKEVFLRELISNAADALEKIRFLSLSDESVLGEEKKLE 83 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +R+S +K+K L+I+D G+GMT+ ++I++LGTIAKSGT +FLE++ S D LIGQFG Sbjct: 84 IRISANKEKNILSITDTGIGMTKVDLINNLGTIAKSGTSNFLEAI-SKSGGDMSLIGQFG 142 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE---DRGTEITLHLR 181 VGFYSAF+VADKV V T+ ++ WES + ++T+ + RGT I+LHL+ Sbjct: 143 VGFYSAFLVADKVIVYTKNNDDEQ---YIWESTADAKFTIYKDPRGATLKRGTRISLHLK 199 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPV 208 E L+D ++ +ISKYS I P+ Sbjct: 200 EDATNLLNDKKLMDLISKYSQFIQFPI 226 >2XCM-A nrPDB Length = 214 Score = 186 bits (471), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 94/209 (44%), Positives = 146/209 (69%), Gaps = 8/209 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QLL L+I++ YSNKEIFLRELISN+SDA DK+RF +L++ + EL Sbjct: 9 ETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPELF 68 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + DK TLTI D+G+GMT+ +++++LGTIA+SGTK F+E+L + D +IGQFG Sbjct: 69 IHIIPDKATSTLTIVDSGIGMTKSDLVNNLGTIARSGTKEFMEALAA--GADVSMIGQFG 126 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKED--RGTEITLHLR 181 VGFYSA++VA++V V T+ + WES G +TV D + E RGT++ L+L+ Sbjct: 127 VGFYSAYLVAERVVVTTK---HNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKMVLYLK 183 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEI 210 + + E+L++ R++ ++ K+S+ I+ P+ + Sbjct: 184 DDQMEYLEERRIKDLVKKHSEFISYPISL 212 >1YT0-A nrPDB Length = 236 Score = 183 bits (465), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 103/230 (44%), Positives = 145/230 (63%), Gaps = 9/230 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 10 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELT 69 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLG---SDQAKDSQLIG 121 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LIG Sbjct: 70 VKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIG 129 Query: 122 QFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLH 179 QFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 130 QFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITLV 186 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEI-EKREEKDGETVISWEKIN 228 L+E ++L+ +++++ KYS I P+ + + G+TV WE +N Sbjct: 187 LKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTGGGGKTVWDWELMN 236 >5F5R-A nrPDB Length = 238 Score = 180 bits (456), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 91/206 (44%), Positives = 142/206 (68%), Gaps = 6/206 (2%) Query: 9 FQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVS 68 FQ+E K+LL ++ SLYS KE+F+RELISNASDA +KLR + +S+ E+ + + Sbjct: 34 FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALP---EMEIHLQ 90 Query: 69 FDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFY 128 + +K T+TI D G+GMT++E++ +LGTIA+SG+K+FL++L + S++IGQFGVGFY Sbjct: 91 TNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFY 150 Query: 129 SAFIVADKVTVRTRAAGEKPEN-GVFWESAGEGEYTVADITKEDRGTEITLHLREGEDEF 187 SAF+VAD+V V +R+A P + G W S G G + +A+ + GT+I +HL+ EF Sbjct: 151 SAFMVADRVEVYSRSAA--PGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEF 208 Query: 188 LDDWRVRSIISKYSDHIALPVEIEKR 213 + RVR +++KYS+ ++ P+ + R Sbjct: 209 SSEARVRDVVTKYSNFVSFPLYLNGR 234 >6D28-A nrPDB Length = 273 Score = 178 bits (451), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 97/211 (45%), Positives = 136/211 (64%), Gaps = 8/211 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 10 EKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELT 69 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLG---SDQAKDSQLIG 121 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LIG Sbjct: 70 VKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIG 129 Query: 122 QFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLH 179 QFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 130 QFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITLV 186 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEI 210 L+E ++L+ +++++ KYS I P+ + Sbjct: 187 LKEEASDYLELDTIKNLVKKYSQFINFPIYV 217 >1Y6Z-A nrPDB Length = 263 Score = 175 bits (444), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 94/260 (36%), Positives = 151/260 (58%), Gaps = 7/260 (2%) Query: 233 LWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNR- 291 +W +++ +T+ +Y FYK+ ++DPL + H VEG+ + S+LYIP PW++ Sbjct: 6 IWKQDEKSLTENDYYSFYKNTFKAYDDPLAYVHFNVEGQISFNSILYIPGSLPWELSKNM 65 Query: 292 --DHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR 349 + G++LYV+RVFI D + +P +L F+RG++DS +LPLNV REILQ S + + Sbjct: 66 FDEESRGIRLYVKRVFINDKFSESIPRWLTFLRGIVDSENLPLNVGREILQKSKMLSIIN 125 Query: 350 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS 409 + + + M++ L + +K+ F FG LK G ED NQE IA L+ F S +S Sbjct: 126 KRIVLKSISMMKGLKETGGDKWTKFLNTFGKYLKIGVVEDKENQEEIASLVEFYS--INS 183 Query: 410 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM 469 + L+ Y+ MKE Q+ IYYI+ ++ A++SP LE L+ +VL + IDE+ + Sbjct: 184 GDKKTDLDSYIENMKEDQKCIYYISGENKKTAQNSPSLEKLKALNYDVLFSLEPIDEFCL 243 Query: 470 NYLT--EFDGKPFQSVSKVD 487 + LT ++ G V+K D Sbjct: 244 SSLTVNKYKGYEVLDVNKAD 263 >3IED-A nrPDB Length = 272 Score = 166 bits (421), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 99/253 (39%), Positives = 150/253 (59%), Gaps = 55/253 (21%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E F++EV +++ ++++SLY++K++FLRELISNASDA DK R L N L + D E+ Sbjct: 25 EKYNFKAEVNKVMDIIVNSLYTDKDVFLRELISNASDACDKKRI-ILENNKLIK-DAEVV 82 Query: 65 VRVSF--------------------------------------DKDKRTLTISDNGVGMT 86 DK+K+TLTI+DNG+GM Sbjct: 83 TNEEIKNETEKEKTENVNESTDKKENVEEEKNDIKKLIIKIKPDKEKKTLTITDNGIGMD 142 Query: 87 RDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGE 146 + E+I++LGTIA+SGT FL+ + +A DS LIGQFGVGFYS+F+V+++V V T Sbjct: 143 KSELINNLGTIAQSGTAKFLKQIEEGKA-DSNLIGQFGVGFYSSFLVSNRVEVYT----- 196 Query: 147 KPENGVF-WESAGEGEYTVADITKEDR--------GTEITLHLREGEDEFLDDWRVRSII 197 K E+ ++ W S +G ++V +I K D+ GT+I LHL+E DE+L+D++++ +I Sbjct: 197 KKEDQIYRWSSDLKGSFSVNEIKKYDQEYDDIKGSGTKIILHLKEECDEYLEDYKLKELI 256 Query: 198 SKYSDHIALPVEI 210 KYS+ I P+EI Sbjct: 257 KKYSEFIKFPIEI 269 >2AKP-A nrPDB Length = 186 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 85/188 (45%), Positives = 134/188 (71%), Gaps = 8/188 (4%) Query: 26 SNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGM 85 SNKEIFLRELISNASDA DK+R+++LS+P E + +L +R++ +++ L I D+G+GM Sbjct: 1 SNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGM 60 Query: 86 TRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAG 145 T+ E+I++LGTIAKSGTK+F+E+L + D +IGQFGVGFYS F+VAD+V V +++ Sbjct: 61 TKAELINNLGTIAKSGTKAFMEALSA--GADVSMIGQFGVGFYSLFLVADRVQVISKSND 118 Query: 146 EKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLHLREGEDEFLDDWRVRSIISKYSD 202 ++ WES G +TV D E RGT + L L++ + E+L++ R++ +I ++S+ Sbjct: 119 DEQ---YIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSE 175 Query: 203 HIALPVEI 210 +A P+++ Sbjct: 176 FVAYPIQL 183 >3D36-A nrPDB Length = 244 Score = 32.7 bits (73), Expect = 0.53, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 24/35 (68%), Gaps = 1/35 (2%) Query: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLG 95 G L+V VS D + + I+D GVGMT+++ ++ LG Sbjct: 143 GTLQVYVSIDNGRVLIRIADTGVGMTKEQ-LERLG 176 >4WBY-A nrPDB Length = 410 Score = 32.3 bits (72), Expect = 0.64, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 8/79 (10%) Query: 485 KVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDAD 544 KV E++E++A EV + AKE L +I +G V+D+ L + D +V +A Sbjct: 4 KVPENIEEIAREVGQIAKEM--GLRAYI------VGGVVRDILLGKEVWDVDFVVEGNAI 55 Query: 545 EMSTQMAKLFAAAGQKVPE 563 E++ ++A+ PE Sbjct: 56 ELAKELARRHGVNVHPFPE 74 >3EYJ-A nrPDB Length = 323 Score = 32.0 bits (71), Expect = 0.77, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 11/88 (12%) Query: 157 AGEGEYTVADITKEDRGTEITLHL-----REGEDEFLDDWRV---RSIISKYSDHIALPV 208 A G Y ++TKE+ G+ + L+L ++E D ++V R +S SD I++ Sbjct: 149 ATNGNYGPINVTKENTGSYVRLYLWGVHHPSSDNEQTDLYKVATGRVTVSTRSDQISIVP 208 Query: 209 EIEKRE---EKDGETVISWEKINKAQAL 233 I R + G I W +N ++ Sbjct: 209 NIGSRPRVRNQSGRISIYWTLVNPGDSI 236 >2F6S-A nrPDB Length = 201 Score = 32.0 bits (71), Expect = 0.81, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 224 WEKINKAQALWTRNKSEITDEEYKEFYK-HIAHDFNDPLT 262 W++I+KA L +S + D E K K H++ + NDPLT Sbjct: 146 WDRIDKAAYLSAMERSPVNDLEIKTLLKKHLSSNTNDPLT 185 >4O8A-A nrPDB Length = 687 Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 9/84 (10%) Query: 462 DRIDEWMM-----NYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVK 516 DR W++ +YL + + ++ ++ L A+E DE+ AE+ PF+D + Sbjct: 26 DRTPHWLIKQAIFSYLEQLENS--DTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAE 83 Query: 517 ALLGERVKDVRLT--HRLTDTPAI 538 +L + V +T +R +T A+ Sbjct: 84 QILPQSVSRAAITAAYRRPETEAV 107 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2O1V-A nrPDB 825 0.0 2IOQ-A nrPDB 822 0.0 5FWK-A nrPDB 821 0.0 2CG9-A nrPDB 819 0.0 1Y4U-A nrPDB 742 0.0 5TTH-B nrPDB 738 0.0 2O1W-A nrPDB 675 0.0 4Z1F-A nrPDB 617 e-177 3HJC-A nrPDB 521 e-148 2CGE-A nrPDB 520 e-148 2O1T-A nrPDB 518 e-147 3Q6N-A nrPDB 513 e-145 1HK7-A nrPDB 399 e-111 1USV-A nrPDB 378 e-105 3PRY-A nrPDB 372 e-103 2GQ0-A nrPDB 367 e-102 6B9A-B nrPDB 336 2e-92 5UCI-A nrPDB 335 4e-92 5J6L-A nrPDB 330 1e-90 3K60-A nrPDB 330 1e-90 1Y6Z-A nrPDB 326 2e-89 3Q5K-A nrPDB 326 2e-89 4X9L-A nrPDB 323 1e-88 5NYI-A nrPDB 323 2e-88 3OMU-A nrPDB 321 4e-88 4GQT-A nrPDB 319 2e-87 2XCM-A nrPDB 318 4e-87 1YT0-A nrPDB 316 2e-86 1BGQ-A nrPDB 315 3e-86 4XDM-A nrPDB 312 3e-85 2IOR-A nrPDB 312 4e-85 6CJJ-A nrPDB 311 4e-85 6D28-A nrPDB 294 9e-80 5F5R-A nrPDB 290 1e-78 3PEH-A nrPDB 280 1e-75 2AKP-A nrPDB 276 3e-74 3IED-A nrPDB 224 1e-58 1SF8-A nrPDB 140 1e-33 Sequences not found previously or not previously below threshold: 3F41-A nrPDB 36 0.065 4P7A-A nrPDB 33 0.27 2PX0-A nrPDB 33 0.30 5Y63-A nrPDB 33 0.38 3D36-A nrPDB 33 0.49 1T7V-A nrPDB 32 0.88 2HK1-A nrPDB 32 1.0 6IGC-A nrPDB 31 1.4 6C96-A nrPDB 31 1.6 4ADY-A nrPDB 31 1.7 3V7C-A nrPDB 31 2.0 6IGE-A nrPDB 30 2.2 5Y5Z-N nrPDB 30 2.4 2R5J-A nrPDB 30 2.5 1D4E-A nrPDB 30 3.1 1MX0-A nrPDB 29 5.3 3FHO-A nrPDB 29 5.3 1Q78-A nrPDB 29 5.9 2ZBK-B nrPDB 29 6.8 5JUT-YA nrPDB 29 7.7 CONVERGED! >2O1V-A nrPDB Length = 666 Score = 825 bits (2132), Expect = 0.0, Method: Composition-based stats. Identities = 253/643 (39%), Positives = 379/643 (58%), Gaps = 33/643 (5%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 22 SEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEEL 81 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESL---GSDQAKDSQLI 120 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LI Sbjct: 82 TVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELI 141 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITL 178 GQFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 142 GQFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITL 198 Query: 179 HLREGEDEFLDDWRVRSIISKYSDHIALPVEI-EKREEKDGETVISWEKINKAQALWTRN 237 L+E ++L+ +++++ KYS I P+ + + G+TV WE +N + +W R Sbjct: 199 VLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTGGGGKTVWDWELMNDIKPIWQRP 258 Query: 238 KSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP---WDMWNRDHK 294 E+ D+EYK FYK + + +DP+ + H EG+ + S+L++P+ AP +D + Sbjct: 259 SKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKS 318 Query: 295 HGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTK 354 +KLYV+RVFI DD MP YL FV+G++DS DLPLNVSRE LQ + + +R L + Sbjct: 319 DYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVR 378 Query: 355 RVLQMLEKLAKDDAEKYQ-TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQT 413 + L M++K+A EKY TFW++FG +K G ED +N+ +AKLLRF S+H S Sbjct: 379 KTLDMIKKIAD---EKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPS--DI 433 Query: 414 VSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLT 473 SL+ YV RMKE Q+KIY++ S A+SSP +E L KKG EV+ L++ +DE+ + L Sbjct: 434 TSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALP 493 Query: 474 EFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKA-LLGERVKDVRLTHRL 532 EFDGK FQ+V+K ++ +++ ES + EK P ++ +K L ++++ ++ RL Sbjct: 494 EFDGKRFQNVAKEGVKFDE-SEKTKESREAIEKEFEPLLNWMKDKALKDKIEKAVVSQRL 552 Query: 533 TDTPAIVSTDADEMSTQMAKLFAAA----GQKVPEVKY-----IFELNPDHVLVK----R 579 T++P + S M ++ A G+ + Y FE+NP H L+K R Sbjct: 553 TESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRR 612 Query: 580 AADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 + ED+ S+ +L + A L L D + R+ ++L Sbjct: 613 VKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERML 655 >2IOQ-A nrPDB Length = 624 Score = 822 bits (2124), Expect = 0.0, Method: Composition-based stats. Identities = 624/624 (100%), Positives = 624/624 (100%) Query: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD Sbjct: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 Query: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI Sbjct: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL Sbjct: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE Sbjct: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 Query: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY Sbjct: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 Query: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML Sbjct: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 Query: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV Sbjct: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 Query: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF Sbjct: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 Query: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS Sbjct: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 Query: 541 TDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQA 600 TDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQA Sbjct: 541 TDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQA 600 Query: 601 LLAERGTLEDPNLFIRRMNQLLVS 624 LLAERGTLEDPNLFIRRMNQLLVS Sbjct: 601 LLAERGTLEDPNLFIRRMNQLLVS 624 >5FWK-A nrPDB Length = 727 Score = 821 bits (2120), Expect = 0.0, Method: Composition-based stats. Identities = 245/680 (36%), Positives = 390/680 (57%), Gaps = 72/680 (10%) Query: 6 TRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRV 65 T FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL++ Sbjct: 17 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKI 76 Query: 66 RVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGV 125 + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFGV Sbjct: 77 DIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFGV 134 Query: 126 GFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLREG 183 GFYSA++VA+KV V T+ + WES+ G +TV E RGT++ LHL+E Sbjct: 135 GFYSAYLVAEKVVVITK---HNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKED 191 Query: 184 EDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGET----------------------- 220 + E+L++ RV+ ++ K+S I P+ + +E++ E Sbjct: 192 QTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKP 251 Query: 221 ---------------------------VISWEKINKAQALWTRNKSEITDEEYKEFYKHI 253 I E++NK + +WTRN +IT EEY EFYK + Sbjct: 252 KIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSL 311 Query: 254 AHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLK-LYVQRVFIMDDAEQ 312 +D+ D L H VEG+ E+ +LL+IP +AP+D++ K LYV+RVFIMD ++ Sbjct: 312 TNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDE 371 Query: 313 FMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQ 372 +P YL F+RG++DS DLPLN+SRE+LQ S + + +R + K+ L++ +LA +D E Y+ Sbjct: 372 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA-EDKENYK 430 Query: 373 TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYY 432 F++ F LK G ED N+ +++LLR+ ++ S + SL +YVSRMKE Q+ IYY Sbjct: 431 KFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQ--SGDEMTSLSEYVSRMKETQKSIYY 488 Query: 433 ITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEK 492 IT +S +S +E +RK+G EV+ +++ IDE+ + L EFDGK SV+K Sbjct: 489 ITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKE-GLELP 547 Query: 493 LADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAK 552 +E + +E++ +K +L ++V+ V +++RL +P + T + M + Sbjct: 548 EDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMER 607 Query: 553 LFAAAGQK------VPEVKYIFELNPDHVLV----KRAADTEDEAKFSEWVELLLDQALL 602 + A + K E+NPDH +V ++A +++ + V LL + ALL Sbjct: 608 IMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALL 667 Query: 603 AERGTLEDPNLFIRRMNQLL 622 + +LEDP R+ +++ Sbjct: 668 SSGFSLEDPQTHSNRIYRMI 687 >2CG9-A nrPDB Length = 677 Score = 819 bits (2115), Expect = 0.0, Method: Composition-based stats. Identities = 255/682 (37%), Positives = 403/682 (59%), Gaps = 71/682 (10%) Query: 3 GQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGE 62 ET FQ+E+ QL+ L+I+++YSNKEIFLRELISNASDA DK+R+++LS+P E + + Sbjct: 2 ASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPD 61 Query: 63 LRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQ 122 L +R++ +++ L I D+G+GMT+ E+I++LGTIAKSGTK+F+E+L + D +IGQ Sbjct: 62 LFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSA--GADVSMIGQ 119 Query: 123 FGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLH 179 FGVGFYS F+VAD+V V +++ + WES G +TV D E RGT + L Sbjct: 120 FGVGFYSLFLVADRVQVISKS---NDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLF 176 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVIS---------------- 223 L++ + E+L++ R++ +I ++S+ +A P+++ +E + E I Sbjct: 177 LKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKD 236 Query: 224 ------------------------------WEKINKAQALWTRNKSEITDEEYKEFYKHI 253 E++NK + LWTRN S+IT EEY FYK I Sbjct: 237 EDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSI 296 Query: 254 AHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW-NRDHKHGLKLYVQRVFIMDDAEQ 312 ++D+ DPL H VEG+ E+ ++L+IP +AP+D++ ++ K+ +KLYV+RVFI D+AE Sbjct: 297 SNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAED 356 Query: 313 FMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQ 372 +P +L FV+G++DS DLPLN+SRE+LQ + + + +R + K++++ ++A +D+E+++ Sbjct: 357 LIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIA-EDSEQFE 415 Query: 373 TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYY 432 F+ F +K G ED N+ A+AKLLR+ ST S + SL DYV+RM E Q+ IYY Sbjct: 416 KFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK--SVDELTSLTDYVTRMPEHQKNIYY 473 Query: 433 ITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEK 492 IT +S A + SP L+ L+ K EVL L+D IDE+ L EF+GK ++K D LE+ Sbjct: 474 ITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITK-DFELEE 532 Query: 493 LADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAK 552 +E E KE K P +K +LG++V+ V ++++L D PA + T S M + Sbjct: 533 TDEEKAEREKEI-KEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMER 591 Query: 553 LFAAAGQKV------PEVKYIFELNPDHVLVKRAADTED-----EAKFSEWVELLLDQAL 601 + A + K FE++P ++K D + + +LL + AL Sbjct: 592 IMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETAL 651 Query: 602 LAERGTLEDPNLFIRRMNQLLV 623 L +L++P F R+N+L+ Sbjct: 652 LTSGFSLDEPTSFASRINRLIS 673 >1Y4U-A nrPDB Length = 559 Score = 742 bits (1915), Expect = 0.0, Method: Composition-based stats. Identities = 559/559 (100%), Positives = 559/559 (100%) Query: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD Sbjct: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 Query: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI Sbjct: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL Sbjct: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE Sbjct: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE 240 Query: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY Sbjct: 241 ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLY 300 Query: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML Sbjct: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 Query: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV Sbjct: 361 EKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYV 420 Query: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF Sbjct: 421 SRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 Query: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS Sbjct: 481 QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVS 540 Query: 541 TDADEMSTQMAKLFAAAGQ 559 TDADEMSTQMAKLFAAAGQ Sbjct: 541 TDADEMSTQMAKLFAAAGQ 559 >5TTH-B nrPDB Length = 672 Score = 738 bits (1905), Expect = 0.0, Method: Composition-based stats. Identities = 222/634 (35%), Positives = 366/634 (57%), Gaps = 38/634 (5%) Query: 6 TRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRV 65 FQ+E K+LL ++ SLYS KE+F+RELISN SDA +KLR R ++ + + Sbjct: 36 KHEFQAETKKLLDIVARSLYSEKEVFIRELISNGSDALEKLRHRMITAG---GDTAPMEI 92 Query: 66 RVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGV 125 + D K T TI D GVGM +++++ +LGTIA+SG+K+FL++L + S +IGQFGV Sbjct: 93 HLQTDSVKGTFTIQDTGVGMNKEDLVSNLGTIARSGSKAFLDALQNQAEASSSIIGQFGV 152 Query: 126 GFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHLREGED 185 GFYSAF+VADKV V +++A E G W S G G + VA+ + +GT+I LHL++ Sbjct: 153 GFYSAFMVADKVEVYSQSA-EADAPGYKWSSDGSGVFEVAEASGVRQGTKIVLHLKDDCK 211 Query: 186 EFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEITDEE 245 EF + RV+ +++KYS+ ++ P+ + R ++N QALW +I++ + Sbjct: 212 EFSSEDRVKEVVTKYSNFVSFPIFLNGR------------RLNTLQALWMMEPKDISEWQ 259 Query: 246 YKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP--WDMWNRDHKHGLKLYVQR 303 ++EFY+++A ++ P H R + S+ Y+P P +D+ +R+ + LY ++ Sbjct: 260 HEEFYRYVAQAYDKPRYTLHYRADAPLNIRSIFYVPEMKPSMFDV-SREMGSSVALYSRK 318 Query: 304 VFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKL 363 + I A +P +LRF+RG++DS D+PLN+S E+LQ+S + R LR+ L +RV++ L Sbjct: 319 ILIQTKATDILPKWLRFLRGVVDSEDIPLNLSAELLQESALIRKLRDVLQQRVIRFLLDQ 378 Query: 364 AKDDAEKYQTFWQQFGLVLKEGPA--EDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVS 421 +K D EKY F++ +GL ++EG + + +E IAKLLRF S+ + Q SL +Y S Sbjct: 379 SKKDPEKYARFFEDYGLFMREGIVTTGEQSVKEDIAKLLRFESSALPAGQQ-TSLMEYSS 437 Query: 422 RMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQ 481 RMK G IYY+ A + A+ SP+ E +++K +EVL ++ DE + +L EFD K Sbjct: 438 RMKAGTRNIYYLCAPNRHLAEHSPYFEAMKQKDMEVLFCFEQFDELTLLHLREFDRKKLI 497 Query: 482 SVSKVDESLEKLADEVDESAKEAEKAL-----TPFIDRVKALLGERVKDVRLTHRLTDTP 536 S ++ D ++ +E + +K A + L + ++ L +RV ++++T RL P Sbjct: 498 S-AETDIVVDHYKEEKFQDSKPASERLSSEQAEDLLAWMRNALVQRVTNIKVTPRLDTHP 556 Query: 537 AIVST---DADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWV 593 A+++ A + +L ++ ++ ++ E+N H L+K+ +D E Sbjct: 557 AMITVLEMGAARHFLRTQQLARSSEERAQILQPTLEINTGHDLIKKLHALKDSN--PELA 614 Query: 594 ELLLDQ----ALLAERGTLEDPNLFIRRMNQLLV 623 +LLL+Q A++A EDP I R+NQLL Sbjct: 615 QLLLEQIYDNAMIAAG-LNEDPRPMISRLNQLLT 647 >2O1W-A nrPDB Length = 506 Score = 675 bits (1741), Expect = 0.0, Method: Composition-based stats. Identities = 219/493 (44%), Positives = 312/493 (63%), Gaps = 18/493 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 22 SEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEEL 81 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESL---GSDQAKDSQLI 120 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LI Sbjct: 82 TVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELI 141 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITL 178 GQFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 142 GQFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITL 198 Query: 179 HLREGEDEFLDDWRVRSIISKYSDHIALPVEI-EKREEKDGETVISWEKINKAQALWTRN 237 L+E ++L+ +++++ KYS I P+ + + G+TV WE +N + +W R Sbjct: 199 VLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTGGGGKTVWDWELMNDIKPIWQRP 258 Query: 238 KSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP---WDMWNRDHK 294 E+ D+EYK FYK + + +DP+ + H EG+ + S+L++P+ AP +D + Sbjct: 259 SKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKS 318 Query: 295 HGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTK 354 +KLYV+RVFI DD MP YL FV+G++DS DLPLNVSRE LQ + + +R L + Sbjct: 319 DYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVR 378 Query: 355 RVLQMLEKLAKDDAEKYQ-TFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQT 413 + L M++K+A EKY TFW++FG +K G ED +N+ +AKLLRF S+H S Sbjct: 379 KTLDMIKKIAD---EKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPS--DI 433 Query: 414 VSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLT 473 SL+ YV RMKE Q+KIY++ S A+SSP +E L KKG EV+ L++ +DE+ + L Sbjct: 434 TSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALP 493 Query: 474 EFDGKPFQSVSKV 486 EFDGK FQ+V+K Sbjct: 494 EFDGKRFQNVAKE 506 >4Z1F-A nrPDB Length = 502 Score = 617 bits (1592), Expect = e-177, Method: Composition-based stats. Identities = 186/497 (37%), Positives = 302/497 (60%), Gaps = 23/497 (4%) Query: 3 GQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGE 62 FQ+E K+LL ++ SLYS KE+F+RELISNASDA +KLR + +S+ E Sbjct: 25 STSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQAL---PE 81 Query: 63 LRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQ 122 + + + + +K T+TI D G+GMT++E++ +LGTIA+SG+K+FL++L + S++IGQ Sbjct: 82 MEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQ 141 Query: 123 FGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHLRE 182 FGVGFYSAF+VAD+V V +R+A G W S G G + +A+ + GT+I +HL+ Sbjct: 142 FGVGFYSAFMVADRVEVYSRSAAPGS-LGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKS 200 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEIT 242 EF + RVR +++KYS+ ++ P+ + R ++N QA+W + ++ Sbjct: 201 DCKEFSSEARVRDVVTKYSNFVSFPLYLNGR------------RMNTLQAIWMMDPKDVR 248 Query: 243 DEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP--WDMWNRDHKHGLKLY 300 + +++EFY+++A + P H + + S+ Y+P P +D+ +R+ + LY Sbjct: 249 EWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDV-SRELGSSVALY 307 Query: 301 VQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQML 360 ++V I A +P +LRF+RG++DS D+PLN+SRE+LQ+S + R LR+ L +R+++ Sbjct: 308 SRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFF 367 Query: 361 EKLAKDDAEKYQTFWQQFGLVLKEGP--AEDFANQEAIAKLLRFASTHTDSSAQTVSLED 418 +K DAEKY F++ +GL ++EG A + +E IAKLLR+ S+ S Q SL + Sbjct: 368 IDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSG-QLTSLSE 426 Query: 419 YVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGK 478 Y SRM+ G IYY+ A + A+ SP+ E ++KK EVL ++ DE + +L EFD K Sbjct: 427 YASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKK 486 Query: 479 PFQSVSKVDESLEKLAD 495 SV + D ++ + Sbjct: 487 KLISV-ETDIVVDHYKE 502 >3HJC-A nrPDB Length = 444 Score = 521 bits (1343), Expect = e-148, Method: Composition-based stats. Identities = 146/403 (36%), Positives = 245/403 (60%), Gaps = 15/403 (3%) Query: 231 QALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWN 290 + LWTR+ ++T EEY FYK I++D+ DP H VEG+ E+ S++++P +AP+DM+ Sbjct: 20 KPLWTRDPKDVTKEEYAAFYKAISNDWEDPAATKHFSVEGQLEFRSIMFVPKRAPFDMFE 79 Query: 291 -RDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR 349 ++ +KLYV+RVFIMD+ E P++L FV+G++DS DLPLN+SRE LQ + + + +R Sbjct: 80 PNKKRNNIKLYVRRVFIMDNCEDLCPDWLGFVKGVVDSEDLPLNISRENLQQNKILKVIR 139 Query: 350 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS 409 + K+ L+M +++A ++ E Y+ F++QFG +K G ED AN++ + +LLRF ST +S Sbjct: 140 KNIVKKCLEMFDEVA-ENKEDYKQFYEQFGKNIKLGIHEDTANRKKLMELLRFYST--ES 196 Query: 410 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM 469 + +L+DYV+RMK GQ+ IYYIT DS ++SP +E R++G+EVL +++ IDE++M Sbjct: 197 GEEMTTLKDYVTRMKAGQKSIYYITGDSKKKLETSPFIEQARRRGLEVLFMTEPIDEYVM 256 Query: 470 NYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLT 529 + +F+ K F ++K E+ + + +E + A +K +LG++V+ V ++ Sbjct: 257 QQVKDFEDKKFACLTKEGVHFEESEE-EKQQREEEKAACEKLCKTMKEVLGDKVEKVIVS 315 Query: 530 HRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEV------KYIFELNPDHVLVK----R 579 RL+ +P I+ T S M ++ + + K ELNP H ++K R Sbjct: 316 ERLSTSPCILVTSEFGWSAHMEQIMRNQALRDSSMAQYMMSKKTMELNPRHPIIKELRRR 375 Query: 580 AADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 E++ + V LL D +LL LEDP + R+N+++ Sbjct: 376 VGADENDKAVKDLVFLLFDTSLLTSGFQLEDPTGYAERINRMI 418 >2CGE-A nrPDB Length = 405 Score = 520 bits (1340), Expect = e-148, Method: Composition-based stats. Identities = 154/406 (37%), Positives = 243/406 (59%), Gaps = 17/406 (4%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 + LWTRN S+IT EEY FYK I++D+ DPL H VEG+ E+ ++L+IP +AP+D++ Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 290 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 348 ++ K+ +KLYV+RVFI D+AE +P +L FV+G++DS DLPLN+SRE+LQ + + + + Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 349 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 408 R + K++++ ++A +D+E+++ F+ F +K G ED N+ A+AKLLR+ ST Sbjct: 121 RKNIVKKLIEAFNEIA-EDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK-- 177 Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 468 S + SL DYV+RM E Q+ IYYIT +S A + SP L+ L+ K EVL L+D IDE+ Sbjct: 178 SVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYA 237 Query: 469 MNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRL 528 L EF+GK ++K D LE+ +E E KE K P +K +LG++V+ V + Sbjct: 238 FTQLKEFEGKTLVDITK-DFELEETDEEKAEREKEI-KEYEPLTKALKEILGDQVEKVVV 295 Query: 529 THRLTDTPAIVSTDADEMSTQMAKLFAAAGQKV------PEVKYIFELNPDHVLVKRAAD 582 +++L D PA + T S M ++ A + K FE++P ++K Sbjct: 296 SYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKK 355 Query: 583 TED-----EAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLV 623 D + + +LL + ALL +L++P F R+N+L+ Sbjct: 356 RVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLIS 401 >2O1T-A nrPDB Length = 450 Score = 518 bits (1335), Expect = e-147, Method: Composition-based stats. Identities = 151/414 (36%), Positives = 236/414 (57%), Gaps = 24/414 (5%) Query: 227 INKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAP- 285 +N + +W R E+ D+EYK FYK + + +DP+ + H EG+ + S+L++P+ AP Sbjct: 21 MNDIKPIWQRPSKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 80 Query: 286 --WDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDST 343 +D + +KLYV+RVFI DD MP YL FV+G++DS DLPLNVSRE LQ Sbjct: 81 GLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHK 140 Query: 344 VTRNLRNALTKRVLQMLEKLAKDDAEKYQ-TFWQQFGLVLKEGPAEDFANQEAIAKLLRF 402 + + +R L ++ L M++K+A EKY TFW++FG +K G ED +N+ +AKLLRF Sbjct: 141 LLKVIRKKLVRKTLDMIKKIAD---EKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRF 197 Query: 403 ASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSD 462 S+H S SL+ YV RMKE Q+KIY++ S A+SSP +E L KKG EV+ L++ Sbjct: 198 QSSHHPS--DITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTE 255 Query: 463 RIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKA-LLGE 521 +DE+ + L EFDGK FQ+V+K ++ +++ ES + EK P ++ +K L + Sbjct: 256 PVDEYCIQALPEFDGKRFQNVAKEGVKFDE-SEKTKESREAIEKEFEPLLNWMKDKALKD 314 Query: 522 RVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAA----GQKVPEVKY-----IFELNP 572 +++ ++ RLT++P + S M ++ A G+ + Y FE+NP Sbjct: 315 KIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP 374 Query: 573 DHVLVK----RAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 H L+K R + ED+ S+ +L + A L L D + R+ ++L Sbjct: 375 RHPLIKDMLRRVKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERML 428 >3Q6N-A nrPDB Length = 448 Score = 513 bits (1321), Expect = e-145, Method: Composition-based stats. Identities = 145/404 (35%), Positives = 242/404 (59%), Gaps = 15/404 (3%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 + +WTRN +IT+EEY EFYK + +D+ D L H VEG+ E+ +LL++P +AP+D++ Sbjct: 3 TKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLF 62 Query: 290 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 348 NR K+ +KLYV+RVFIMD+ E+ +P YL F+RG++DS DLPLN+SRE+LQ S + + + Sbjct: 63 ENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 122 Query: 349 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 408 R L K+ L++ +LA +D E Y+ F++QF +K G ED N++ +++LLR+ ++ Sbjct: 123 RKNLVKKCLELFTELA-EDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSA-- 179 Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 468 S + VSL+DY +RMKE Q+ IYYIT ++ +S +E LRK G+EV+ + + IDE+ Sbjct: 180 SGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYC 239 Query: 469 MNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRL 528 + L EF+GK SV+K +E + +E + +K +L ++V+ V + Sbjct: 240 VQQLKEFEGKTLVSVTKE-GLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVV 298 Query: 529 THRLTDTPAIVSTDADEMSTQMAKLFAAAGQK------VPEVKYIFELNPDHVLV----K 578 ++RL +P + T + M ++ A + K E+NPDH ++ + Sbjct: 299 SNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQ 358 Query: 579 RAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 622 +A +++ + V LL + ALL+ +LEDP R+ +++ Sbjct: 359 KAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMI 402 >1HK7-A nrPDB Length = 288 Score = 399 bits (1024), Expect = e-111, Method: Composition-based stats. Identities = 127/293 (43%), Positives = 192/293 (65%), Gaps = 6/293 (2%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 + LWTRN S+IT EEY FYK I++D+ DPL H VEG+ E+ ++L+IP +AP+D++ Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 290 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 348 ++ K+ +KLYV+RVFI D+AE +P +L FV+G++DS DLPLN+SRE+LQ + + + + Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 349 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 408 R + K++++ ++A +D+E+++ F+ F +K G ED N+ A+AKLLR+ ST Sbjct: 121 RKNIVKKLIEAFNEIA-EDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK-- 177 Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 468 S + SL DYV+RM E Q+ IYYIT +S A + SP L+ L+ K EVL L+D IDE+ Sbjct: 178 SVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYA 237 Query: 469 MNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGE 521 L EF+GK ++K D LE+ +E E KE K P +K +LG+ Sbjct: 238 FTQLKEFEGKTLVDITK-DFELEETDEEKAEREKEI-KEYEPLTKALKEILGD 288 >1USV-A nrPDB Length = 260 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 116/259 (44%), Positives = 176/259 (67%), Gaps = 4/259 (1%) Query: 229 KAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDM 288 K + LWTRN S+IT EEY FYK I++D+ DPL H VEG+ E+ ++L+IP +AP+D+ Sbjct: 2 KTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDL 61 Query: 289 W-NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRN 347 + ++ K+ +KLYV+RVFI D+AE +P +L FV+G++DS DLPLN+SRE+LQ + + + Sbjct: 62 FESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKV 121 Query: 348 LRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHT 407 +R + K++++ ++A +D+E+++ F+ F +K G ED N+ A+AKLLR+ ST Sbjct: 122 IRKNIVKKLIEAFNEIA-EDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTK- 179 Query: 408 DSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEW 467 S + SL DYV+RM E Q+ IYYIT +S A + SP L+ L+ K EVL L+D IDE+ Sbjct: 180 -SVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEY 238 Query: 468 MMNYLTEFDGKPFQSVSKV 486 L EF+GK ++K Sbjct: 239 AFTQLKEFEGKTLVDITKD 257 >3PRY-A nrPDB Length = 268 Score = 372 bits (955), Expect = e-103, Method: Composition-based stats. Identities = 114/265 (43%), Positives = 172/265 (64%), Gaps = 4/265 (1%) Query: 229 KAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDM 288 K + +WTRN +IT EEY EFYK + +D+ D L H VEG+ E+ +LL+IP +AP+D+ Sbjct: 2 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 61 Query: 289 WNRDHKHGLK-LYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRN 347 + K LYV+RVFIMD ++ +P YL F+RG++DS DLPLN+SRE+LQ S + + Sbjct: 62 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 121 Query: 348 LRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHT 407 +R + K+ L++ +LA +D E Y+ F++ F LK G ED N+ +++LLR+ ++ Sbjct: 122 IRKNIVKKCLELFSELA-EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQ- 179 Query: 408 DSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEW 467 S + SL +YVSRMKE Q+ IYYIT +S +S +E +RK+G EV+ +++ IDE+ Sbjct: 180 -SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEY 238 Query: 468 MMNYLTEFDGKPFQSVSKVDESLEK 492 + L EFDGK SV+K L + Sbjct: 239 CVQQLKEFDGKSLVSVTKEGLELAE 263 >2GQ0-A nrPDB Length = 303 Score = 367 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 266/266 (100%), Positives = 266/266 (100%) Query: 230 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 289 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW Sbjct: 2 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 61 Query: 290 NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR 349 NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR Sbjct: 62 NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLR 121 Query: 350 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS 409 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS Sbjct: 122 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDS 181 Query: 410 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM 469 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM Sbjct: 182 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMM 241 Query: 470 NYLTEFDGKPFQSVSKVDESLEKLAD 495 NYLTEFDGKPFQSVSKVDESLEKLAD Sbjct: 242 NYLTEFDGKPFQSVSKVDESLEKLAD 267 >6B9A-B nrPDB Length = 256 Score = 336 bits (861), Expect = 2e-92, Method: Composition-based stats. Identities = 103/224 (45%), Positives = 153/224 (68%), Gaps = 7/224 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISN+SDA DK+R+ +L++P + EL Sbjct: 38 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELH 97 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + +K RTLTI D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 98 INLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFG 155 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 VGFYSA++VA+KVTV T+ + WES+ G +TV T E RGT++ LHL+E Sbjct: 156 VGFYSAYLVAEKVTVITK---HNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKE 212 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEK 226 + E+L++ R++ I+ K+S I P+ + +E+D E + Sbjct: 213 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAE 256 >5UCI-A nrPDB Length = 220 Score = 335 bits (859), Expect = 4e-92, Method: Composition-based stats. Identities = 96/210 (45%), Positives = 145/210 (69%), Gaps = 7/210 (3%) Query: 6 TRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRV 65 T FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL++ Sbjct: 16 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKI 75 Query: 66 RVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGV 125 + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFGV Sbjct: 76 DIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFGV 133 Query: 126 GFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLREG 183 GFYSA++VA+KV V T+ + WES+ G +TV E RGT++ LHL+E Sbjct: 134 GFYSAYLVAEKVVVITK---HNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKED 190 Query: 184 EDEFLDDWRVRSIISKYSDHIALPVEIEKR 213 + E+L++ RV+ ++ K+S I P+ + Sbjct: 191 QTEYLEERRVKEVVKKHSQFIGYPITLYLE 220 >5J6L-A nrPDB Length = 228 Score = 330 bits (846), Expect = 1e-90, Method: Composition-based stats. Identities = 102/224 (45%), Positives = 152/224 (67%), Gaps = 7/224 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISN+SDA DK+R+ +L++P + EL Sbjct: 10 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELH 69 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + +K RTLTI D G+GMT+ ++I++ GTIAKSGTK+F+E+L + D +IGQFG Sbjct: 70 INLIPNKQDRTLTIVDTGIGMTKADLINNAGTIAKSGTKAFMEALQA--GADISMIGQFG 127 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 VGFYSA++VA+KVTV T+ + WES+ G +TV T E RGT++ LHL+E Sbjct: 128 VGFYSAYLVAEKVTVITK---HNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKE 184 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEK 226 + E+L++ R++ I+ K+S I P+ + +E+D E + Sbjct: 185 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAE 228 >3K60-A nrPDB Length = 223 Score = 330 bits (846), Expect = 1e-90, Method: Composition-based stats. Identities = 97/229 (42%), Positives = 155/229 (67%), Gaps = 10/229 (4%) Query: 3 GQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGE 62 ET F ++++QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ ++++ + E Sbjct: 2 STETFAFNADIRQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESITDTQKLSAEPE 61 Query: 63 LRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQ 122 +R+ DK TLTI D+G+GMT++++I++LGTIA+SGTK+F+E++ + + D +IGQ Sbjct: 62 FFIRIIPDKTNNTLTIEDSGIGMTKNDLINNLGTIARSGTKAFMEAIQA--SGDISMIGQ 119 Query: 123 FGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE---DRGTEITLH 179 FGVGFYSA++VAD V V ++ + WESA G +TV RGT+I LH Sbjct: 120 FGVGFYSAYLVADHVVVISK---NNDDEQYVWESAAGGSFTVTKDETNEKLGRGTKIILH 176 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKIN 228 L+E + E+L++ R++ ++ K+S+ I+ P+++ E+ G WE++N Sbjct: 177 LKEDQLEYLEEKRIKDLVKKHSEFISFPIKLY--CERGGGVEHEWEELN 223 >1Y6Z-A nrPDB Length = 263 Score = 326 bits (835), Expect = 2e-89, Method: Composition-based stats. Identities = 94/261 (36%), Positives = 151/261 (57%), Gaps = 7/261 (2%) Query: 232 ALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNR 291 +W +++ +T+ +Y FYK+ ++DPL + H VEG+ + S+LYIP PW++ Sbjct: 5 PIWKQDEKSLTENDYYSFYKNTFKAYDDPLAYVHFNVEGQISFNSILYIPGSLPWELSKN 64 Query: 292 ---DHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 348 + G++LYV+RVFI D + +P +L F+RG++DS +LPLNV REILQ S + + Sbjct: 65 MFDEESRGIRLYVKRVFINDKFSESIPRWLTFLRGIVDSENLPLNVGREILQKSKMLSII 124 Query: 349 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 408 + + + M++ L + +K+ F FG LK G ED NQE IA L+ F S + Sbjct: 125 NKRIVLKSISMMKGLKETGGDKWTKFLNTFGKYLKIGVVEDKENQEEIASLVEFYS--IN 182 Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 468 S + L+ Y+ MKE Q+ IYYI+ ++ A++SP LE L+ +VL + IDE+ Sbjct: 183 SGDKKTDLDSYIENMKEDQKCIYYISGENKKTAQNSPSLEKLKALNYDVLFSLEPIDEFC 242 Query: 469 MNYLT--EFDGKPFQSVSKVD 487 ++ LT ++ G V+K D Sbjct: 243 LSSLTVNKYKGYEVLDVNKAD 263 >3Q5K-A nrPDB Length = 231 Score = 326 bits (835), Expect = 2e-89, Method: Composition-based stats. Identities = 99/217 (45%), Positives = 152/217 (70%), Gaps = 7/217 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+++L++P + L Sbjct: 20 TETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKIRYQSLTDPSVLGESPRL 79 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQF 123 +RV DK+ +TLT+ DNG+GMT+ +++++LGTIA+SGTK+F+E+L + D +IGQF Sbjct: 80 CIRVVPDKENKTLTVEDNGIGMTKADLVNNLGTIARSGTKAFMEALEA--GGDMSMIGQF 137 Query: 124 GVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLR 181 GVGFYSA++VAD+VTV ++ + WES+ G +T+ + D RGT ITLHL+ Sbjct: 138 GVGFYSAYLVADRVTVTSK---NNSDESYVWESSAGGTFTITSTPESDMKRGTRITLHLK 194 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG 218 E + E+L+ R++ +I K+S+ I +E+ + + Sbjct: 195 EDQMEYLEPRRLKELIKKHSEFIGYDIELMVEKTTEK 231 >4X9L-A nrPDB Length = 250 Score = 323 bits (829), Expect = 1e-88, Method: Composition-based stats. Identities = 95/217 (43%), Positives = 147/217 (67%), Gaps = 8/217 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 ET FQ+E+ QLL L+I++ YSNKEIFLRELISN+SDA DK+RF +L++ + EL Sbjct: 39 TETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPEL 98 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQF 123 + + DK TL+I D+GVGMT+ +++++LGTIA+SGTK F+E+L + D +IGQF Sbjct: 99 FIHIVPDKASNTLSIIDSGVGMTKSDLVNNLGTIARSGTKEFMEALAA--GADVSMIGQF 156 Query: 124 GVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE---DRGTEITLHL 180 GVGFYSA++VA++V V T+ + WES G +TV T RGT+ITL+L Sbjct: 157 GVGFYSAYLVAERVVVTTK---HNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKITLYL 213 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKD 217 ++ + E+L++ R++ ++ K+S+ I+ P+ + + + Sbjct: 214 KDDQLEYLEERRLKDLVKKHSEFISYPISLWTEKTTE 250 >5NYI-A nrPDB Length = 229 Score = 323 bits (828), Expect = 2e-88, Method: Composition-based stats. Identities = 97/224 (43%), Positives = 150/224 (66%), Gaps = 7/224 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET FQ+E+ QL+ L+I++ Y+NKEIFLRELI+N +DA DK+R+ L++P + EL Sbjct: 11 ETFAFQAEIAQLMTLIINTFYTNKEIFLRELITNTTDALDKIRYETLTDPTKLDTGKELH 70 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 + + +K RTLTI D G+GMT+ ++I++LGTIAK+GTK+F+E+L + D +IGQFG Sbjct: 71 INLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKTGTKAFMEALQA--GADITMIGQFG 128 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 VGFY+A++VA+KVTV T+ + WE+ G +TV T E RGT++ LHL+E Sbjct: 129 VGFYTAYLVAEKVTVITK---HNDDEQYAWETTAGGTFTVRTDTGEPMGRGTKVILHLKE 185 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEK 226 + E+L++ R++ I+ K++ I P+ + EE+D E + Sbjct: 186 DQTEYLEERRIKEIVKKHTQFIGYPITLFVEEERDKEVTDDEAE 229 >3OMU-A nrPDB Length = 231 Score = 321 bits (824), Expect = 4e-88, Method: Composition-based stats. Identities = 98/217 (45%), Positives = 151/217 (69%), Gaps = 7/217 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISN+SDA DK+R+++L+N + + L Sbjct: 20 TETFAFQAEINQLMSLIINTFYSNKEIFLRELISNSSDACDKIRYQSLTNQSVLGDEPHL 79 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQF 123 R+RV D+ +TLT+ D+G+GMT+ +++++LGTIA+SGTKSF+E+L + D +IGQF Sbjct: 80 RIRVIPDRVNKTLTVEDSGIGMTKADLVNNLGTIARSGTKSFMEALEA--GGDMSMIGQF 137 Query: 124 GVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLR 181 GVGFYSA++VAD+VTV ++ ++ WES+ G +TV D RGT I LHL+ Sbjct: 138 GVGFYSAYLVADRVTVVSK---NNEDDAYTWESSAGGTFTVTSTPDCDLKRGTRIVLHLK 194 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG 218 E + E+L++ R++ +I K+S+ I +E+ + Sbjct: 195 EDQQEYLEERRLKDLIKKHSEFIGYDIELMVENTTEK 231 >4GQT-A nrPDB Length = 227 Score = 319 bits (818), Expect = 2e-87, Method: Composition-based stats. Identities = 94/209 (44%), Positives = 151/209 (72%), Gaps = 7/209 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 ET FQ+E+ QL+ L+I++ YSNKEI+LRELISNASDA DK+R++AL+ P + EL Sbjct: 8 AETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKEL 67 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQF 123 ++++ +K+++TLTI D G+GMT+ +++++LGTIAKSGTK+F+E+L + D +IGQF Sbjct: 68 FIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQA--GADISMIGQF 125 Query: 124 GVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA--DITKEDRGTEITLHLR 181 GVGFYSAF+VADKV V ++ ++ WES+ G + V + + RGT+I +H++ Sbjct: 126 GVGFYSAFLVADKVVVTSK---NNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIK 182 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEI 210 E + +FL++ +++ I+ K+S I P+++ Sbjct: 183 EDQIDFLEERKIKEIVKKHSQFIGYPIKL 211 >2XCM-A nrPDB Length = 214 Score = 318 bits (816), Expect = 4e-87, Method: Composition-based stats. Identities = 93/210 (44%), Positives = 144/210 (68%), Gaps = 8/210 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 ET FQ+E+ QLL L+I++ YSNKEIFLRELISN+SDA DK+RF +L++ + EL Sbjct: 8 TETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPEL 67 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQF 123 + + DK TLTI D+G+GMT+ +++++LGTIA+SGTK F+E+L + D +IGQF Sbjct: 68 FIHIIPDKATSTLTIVDSGIGMTKSDLVNNLGTIARSGTKEFMEALAA--GADVSMIGQF 125 Query: 124 GVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE---DRGTEITLHL 180 GVGFYSA++VA++V V T+ + WES G +TV T RGT++ L+L Sbjct: 126 GVGFYSAYLVAERVVVTTK---HNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKMVLYL 182 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEI 210 ++ + E+L++ R++ ++ K+S+ I+ P+ + Sbjct: 183 KDDQMEYLEERRIKDLVKKHSEFISYPISL 212 >1YT0-A nrPDB Length = 236 Score = 316 bits (809), Expect = 2e-86, Method: Composition-based stats. Identities = 103/231 (44%), Positives = 145/231 (62%), Gaps = 9/231 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 9 SEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEEL 68 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESL---GSDQAKDSQLI 120 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LI Sbjct: 69 TVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELI 128 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITL 178 GQFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 129 GQFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITL 185 Query: 179 HLREGEDEFLDDWRVRSIISKYSDHIALPVEI-EKREEKDGETVISWEKIN 228 L+E ++L+ +++++ KYS I P+ + + G+TV WE +N Sbjct: 186 VLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTGGGGKTVWDWELMN 236 >1BGQ-A nrPDB Length = 225 Score = 315 bits (808), Expect = 3e-86, Method: Composition-based stats. Identities = 96/218 (44%), Positives = 153/218 (70%), Gaps = 8/218 (3%) Query: 3 GQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGE 62 ET FQ+E+ QL+ L+I+++YSNKEIFLRELISNASDA DK+R+++LS+P E + + Sbjct: 13 ASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPD 72 Query: 63 LRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQ 122 L +R++ +++ L I D+G+GMT+ E+I++LGTIAKSGTK+F+E+L + D +IGQ Sbjct: 73 LFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSA--GADVSMIGQ 130 Query: 123 FGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLH 179 FGVGFYS F+VAD+V V +++ + WES G +TV D E RGT + L Sbjct: 131 FGVGFYSLFLVADRVQVISKS---NDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLF 187 Query: 180 LREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKD 217 L++ + E+L++ R++ +I ++S+ +A P+++ +E + Sbjct: 188 LKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVE 225 >4XDM-A nrPDB Length = 259 Score = 312 bits (799), Expect = 3e-85, Method: Composition-based stats. Identities = 96/215 (44%), Positives = 153/215 (71%), Gaps = 6/215 (2%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E FQ+E+ QL+ L+I++ YSNKE+FLRELISNASDA DK+R+++L++ + E EL Sbjct: 43 ERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELE 102 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +++ DK +TLT+ D+G+GMT+ +++ +LGTIA+SGTK+F+E L S A D +IGQFG Sbjct: 103 IKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQS-GAADISMIGQFG 161 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 VGFYSA++VAD V V ++ + WES+ GE+T+A E RGT+I LH++E Sbjct: 162 VGFYSAYLVADTVIVHSK---NNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKE 218 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKD 217 + ++LD+ ++++++ K+S+ I P+ + +EK+ Sbjct: 219 DQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEKE 253 >2IOR-A nrPDB Length = 235 Score = 312 bits (799), Expect = 4e-85, Method: Composition-based stats. Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 60 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD Sbjct: 21 MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGD 80 Query: 61 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 120 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI Sbjct: 81 GELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLI 140 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 180 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL Sbjct: 141 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHL 200 Query: 181 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREE 215 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREE Sbjct: 201 REGEDEFLDDWRVRSIISKYSDHIALPVEIEKREE 235 >6CJJ-A nrPDB Length = 230 Score = 311 bits (798), Expect = 4e-85, Method: Composition-based stats. Identities = 100/217 (46%), Positives = 152/217 (70%), Gaps = 8/217 (3%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 ET F +E+ QL+ L+I+++YSNKEIFLRELISNASDA DK+R++ALS+P E + EL Sbjct: 19 ETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELF 78 Query: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 +R+ KD++ L I D+G+GMT+ +++++LGTIAKSGTKSF+E+L + D +IGQFG Sbjct: 79 IRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSA--GADVSMIGQFG 136 Query: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLHLR 181 VGFYS F+VAD V V ++ + WES G++TV D T E RGT + L L+ Sbjct: 137 VGFYSLFLVADHVQVISK---HNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLK 193 Query: 182 EGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG 218 E + E+L++ R++ ++ K+S+ +A P+++ +E + Sbjct: 194 EDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEK 230 >6D28-A nrPDB Length = 273 Score = 294 bits (752), Expect = 9e-80, Method: Composition-based stats. Identities = 97/216 (44%), Positives = 137/216 (63%), Gaps = 8/216 (3%) Query: 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGEL 63 E FQ+EV +++ L+I+SLY NKEIFLRELISNASDA DK+R +L++ + G+ EL Sbjct: 9 SEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEEL 68 Query: 64 RVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESL---GSDQAKDSQLI 120 V++ DK+K L ++D GVGMTR+E++ +LGTIAKSGT FL + D S+LI Sbjct: 69 TVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELI 128 Query: 121 GQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITL 178 GQFGVGFYSAF+VADKV V ++ + WES +AD RGT ITL Sbjct: 129 GQFGVGFYSAFLVADKVIVTSKHNNDTQH---IWESDSNEFSVIADPRGNTLGRGTTITL 185 Query: 179 HLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKRE 214 L+E ++L+ +++++ KYS I P+ + + Sbjct: 186 VLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSK 221 >5F5R-A nrPDB Length = 238 Score = 290 bits (742), Expect = 1e-78, Method: Composition-based stats. Identities = 90/212 (42%), Positives = 140/212 (66%), Gaps = 4/212 (1%) Query: 3 GQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGE 62 FQ+E K+LL ++ SLYS KE+F+RELISNASDA +KLR + +S+ E Sbjct: 28 STSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQAL---PE 84 Query: 63 LRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQ 122 + + + + +K T+TI D G+GMT++E++ +LGTIA+SG+K+FL++L + S++IGQ Sbjct: 85 MEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQ 144 Query: 123 FGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHLRE 182 FGVGFYSAF+VAD+V V +R+A G W S G G + +A+ + GT+I +HL+ Sbjct: 145 FGVGFYSAFMVADRVEVYSRSAAPGS-LGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKS 203 Query: 183 GEDEFLDDWRVRSIISKYSDHIALPVEIEKRE 214 EF + RVR +++KYS+ ++ P+ + R Sbjct: 204 DCKEFSSEARVRDVVTKYSNFVSFPLYLNGRR 235 >3PEH-A nrPDB Length = 281 Score = 280 bits (716), Expect = 1e-75, Method: Composition-based stats. Identities = 96/228 (42%), Positives = 148/228 (64%), Gaps = 7/228 (3%) Query: 2 KGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDG 61 + E+ +Q+EV +L+ ++++SLY+ KE+FLRELISNA+DA +K+RF +LS+ + + Sbjct: 21 ESMESHQYQTEVTRLMDIIVNSLYTQKEVFLRELISNAADALEKIRFLSLSDESVLGEEK 80 Query: 62 ELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIG 121 +L +R+S +K+K L+I+D G+GMT+ ++I++LGTIAKSGT +FLE++ S D LIG Sbjct: 81 KLEIRISANKEKNILSITDTGIGMTKVDLINNLGTIAKSGTSNFLEAI-SKSGGDMSLIG 139 Query: 122 QFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE---DRGTEITL 178 QFGVGFYSAF+VADKV V T+ + WES + ++T+ + RGT I+L Sbjct: 140 QFGVGFYSAFLVADKVIVYTK---NNDDEQYIWESTADAKFTIYKDPRGATLKRGTRISL 196 Query: 179 HLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEK 226 HL+E L+D ++ +ISKYS I P+ + E + K Sbjct: 197 HLKEDATNLLNDKKLMDLISKYSQFIQFPIYLLHENVYTEEVLADIAK 244 >2AKP-A nrPDB Length = 186 Score = 276 bits (705), Expect = 3e-74, Method: Composition-based stats. Identities = 85/191 (44%), Positives = 133/191 (69%), Gaps = 8/191 (4%) Query: 26 SNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGM 85 SNKEIFLRELISNASDA DK+R+++LS+P E + +L +R++ +++ L I D+G+GM Sbjct: 1 SNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGM 60 Query: 86 TRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAG 145 T+ E+I++LGTIAKSGTK+F+E+L + D +IGQFGVGFYS F+VAD+V V +++ Sbjct: 61 TKAELINNLGTIAKSGTKAFMEALSA--GADVSMIGQFGVGFYSLFLVADRVQVISKS-- 116 Query: 146 EKPENGVFWESAGEGEYTVA-DITKE--DRGTEITLHLREGEDEFLDDWRVRSIISKYSD 202 + WES G +TV D E RGT + L L++ + E+L++ R++ +I ++S+ Sbjct: 117 -NDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSE 175 Query: 203 HIALPVEIEKR 213 +A P+++ Sbjct: 176 FVAYPIQLVVT 186 >3IED-A nrPDB Length = 272 Score = 224 bits (570), Expect = 1e-58, Method: Composition-based stats. Identities = 94/255 (36%), Positives = 144/255 (56%), Gaps = 53/255 (20%) Query: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 E F++EV +++ ++++SLY++K++FLRELISNASDA DK R + D E+ Sbjct: 25 EKYNFKAEVNKVMDIIVNSLYTDKDVFLRELISNASDACDKKRIIL--ENNKLIKDAEVV 82 Query: 65 VRVS--------------------------------------FDKDKRTLTISDNGVGMT 86 DK+K+TLTI+DNG+GM Sbjct: 83 TNEEIKNETEKEKTENVNESTDKKENVEEEKNDIKKLIIKIKPDKEKKTLTITDNGIGMD 142 Query: 87 RDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGE 146 + E+I++LGTIA+SGT FL+ + + DS LIGQFGVGFYS+F+V+++V V T+ Sbjct: 143 KSELINNLGTIAQSGTAKFLKQIEEGK-ADSNLIGQFGVGFYSSFLVSNRVEVYTK---- 197 Query: 147 KPENGVFWESAGEGEYTVADITKEDR--------GTEITLHLREGEDEFLDDWRVRSIIS 198 K + W S +G ++V +I K D+ GT+I LHL+E DE+L+D++++ +I Sbjct: 198 KEDQIYRWSSDLKGSFSVNEIKKYDQEYDDIKGSGTKIILHLKEECDEYLEDYKLKELIK 257 Query: 199 KYSDHIALPVEIEKR 213 KYS+ I P+EI Sbjct: 258 KYSEFIKFPIEIWSE 272 >1SF8-A nrPDB Length = 126 Score = 140 bits (354), Expect = 1e-33, Method: Composition-based stats. Identities = 114/115 (99%), Positives = 114/115 (99%) Query: 510 PFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFE 569 FIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFE Sbjct: 12 SFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFE 71 Query: 570 LNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS 624 LNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS Sbjct: 72 LNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS 126 >3F41-A nrPDB Length = 629 Score = 35.8 bits (81), Expect = 0.065, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 44/123 (35%), Gaps = 9/123 (7%) Query: 162 YTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIIS--KYSDHIALPVEIEKREEKDGE 219 + D + R +I + L + + L V+SI + I PV + + + E Sbjct: 134 FANHDWGNDGRTEDIIIPLEKEQLASLKGSTVKSIYRFDDKKNVILSPVYVNYNKVRTEE 193 Query: 220 TVISWEKINKAQALWTRN--KSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSL 277 ++ N + + + +++ EFYK + D W H T++ Sbjct: 194 EMVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKD-----AWLHYHCYAGMGRTTI 248 Query: 278 LYI 280 + Sbjct: 249 FMV 251 >4P7A-A nrPDB Length = 348 Score = 33.5 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 33/176 (18%), Positives = 68/176 (38%), Gaps = 27/176 (15%) Query: 74 RTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIV 133 + + I DNG G+ +++ L + + T S L+S G G S V Sbjct: 58 KLIQIQDNGTGIRKED----LDIVCERFTTSKLQSFEDL--ASISTYGFRGEALASISHV 111 Query: 134 ADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLH------------LR 181 A VT+ T+ A K + ++GT+IT+ L+ Sbjct: 112 A-HVTITTKTADGK--CAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRKALK 168 Query: 182 EGEDEFLDDWRVRSIISKYSDH---IALPVEIEKREEKDGETVISWEKINKAQALW 234 +E+ ++ ++ +YS H I+ V+ + D T+ + ++ ++++ Sbjct: 169 NPSEEY---GKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIF 221 >2PX0-A nrPDB Length = 296 Score = 33.5 bits (75), Expect = 0.30, Method: Composition-based stats. Identities = 32/172 (18%), Positives = 68/172 (39%), Gaps = 9/172 (5%) Query: 331 PLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDF 390 PL + ++LQ++ + + + K++L+ + E Q+ + A+ + Sbjct: 41 PLRKAEKLLQETGIKESTKTNTLKKLLRFSVEAGGLTEENVVGKLQEILCDM-LPSADKW 99 Query: 391 ANQEAIAKLLRFASTHTDSSAQTVSLEDYVS-RMKEGQEKIYYITADSYA--AAKSSPHL 447 ++ F ST + +T +L + M E +KI +IT D+Y A + Sbjct: 100 QEPIHSKYIVLFGST---GAGKTTTLAKLAAISMLEKHKKIAFITTDTYRIAAVEQLKTY 156 Query: 448 ELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDE 499 L + +EV + + +E+D F + + + DE+ E Sbjct: 157 AELLQAPLEVCYTKEEFQQ-AKELFSEYD-HVFVDTAGRNFKDPQYIDELKE 206 >5Y63-A nrPDB Length = 183 Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 46/104 (44%), Gaps = 19/104 (18%) Query: 4 QETRGFQSEVK-QLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPD------- 55 QE E+ ++ + S Y +K ++A++ K+++ L++P+ Sbjct: 66 QEHYAHLQELNCEVYSVSEDSHYVHKAW------ADATETIGKIKYPMLADPNGQLARFF 119 Query: 56 -LYEGDGELRVR----VSFDKDKRTLTISDNGVGMTRDEVIDHL 94 + + + R VS + D ++ I+D G+G +E++ L Sbjct: 120 GVLDEASGMAYRASFIVSPEGDIKSYEINDMGIGRNAEELVRKL 163 >3D36-A nrPDB Length = 244 Score = 32.7 bits (73), Expect = 0.49, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 22/36 (61%) Query: 55 DLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEV 90 + G L+V VS D + + I+D GVGMT++++ Sbjct: 137 EAMPNGGTLQVYVSIDNGRVLIRIADTGVGMTKEQL 172 >1T7V-A nrPDB Length = 278 Score = 31.9 bits (71), Expect = 0.88, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 35/90 (38%), Gaps = 19/90 (21%) Query: 247 KEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWD---MWNRDHKHGLKLYVQR 303 F+K+ + D + E IP+ P+D + +YVQR Sbjct: 112 GAFWKY----YYDGKDYIEFNKE----------IPAWVPFDPAAQITKQKWEAEPVYVQR 157 Query: 304 V--FIMDDAEQFMPNYLRFVRGLIDSSDLP 331 ++ ++ + YL++ + ++D D P Sbjct: 158 AKAYLEEECPATLRKYLKYSKNILDRQDPP 187 >2HK1-A nrPDB Length = 309 Score = 31.6 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 10/64 (15%) Query: 423 MKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQS 482 MK G IYY + +AK P++E + K G +++ E +++ E+ + Sbjct: 21 MKHG---IYYSYWEHEWSAKFGPYIEKVAKLGFDII-------EVAAHHINEYSDAELAT 70 Query: 483 VSKV 486 + K Sbjct: 71 IRKS 74 >6IGC-A nrPDB Length = 524 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 5/39 (12%) Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHL 447 ++ VS ++YVSR IYY S A +P+ Sbjct: 43 PVSKVVSTDEYVSR-----TSIYYYAGSSRLLAVGNPYF 76 >6C96-A nrPDB Length = 825 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 14/95 (14%), Positives = 32/95 (33%), Gaps = 11/95 (11%) Query: 386 PAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSP 445 E ++E + +L +S+ L D +S+M++ Q+ Sbjct: 711 VIEKEMSKEELMAVLELYREERGTSSDVTRLLDTLSQMEKYQQNSMVFLGRRSRT----- 765 Query: 446 HLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF 480 K + + + + I EW + E + + Sbjct: 766 ------KSDLSLKMYQEEIQEWYEEHAREQEQQKL 794 >4ADY-A nrPDB Length = 963 Score = 30.8 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 21/168 (12%), Positives = 53/168 (31%), Gaps = 18/168 (10%) Query: 350 NALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAED---------FANQEAIAKLL 400 + + ++M + A K + F+ + + K + + A+ L Sbjct: 110 ETIVSKSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIAL 169 Query: 401 RFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLL 460 SA L+ + E + I Y+ + +S + +K + L+ Sbjct: 170 EGYRLDIIESALKSKLDQDST--SENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMN 227 Query: 461 SDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL 508 D +N K +++ +L+ +E+ + + Sbjct: 228 MPNCDYLTLN-------KVVVNLNDAGLALQLFKKLKEENDEGLSAQI 268 >3V7C-A nrPDB Length = 329 Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 166 DITKEDRGTEITLHLREGEDEF-LDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISW 224 D + R T I LH + D + + ++ I +Y+ + LP + E + + Sbjct: 221 DESIRHRATSIQLHDKNKLDRYQFLERLLQEIEKRYNQFLTLPFSEIREEYIAASNIWNR 280 Query: 225 EKI 227 + Sbjct: 281 TLL 283 >6IGE-A nrPDB Length = 499 Score = 30.4 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 17/39 (43%), Gaps = 5/39 (12%) Query: 409 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHL 447 ++ VS ++YVSR IYY S A P+ Sbjct: 17 PVSKVVSTDEYVSR-----TSIYYYAGSSRLLAVGHPYF 50 >5Y5Z-N nrPDB Length = 652 Score = 30.4 bits (67), Expect = 2.4, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 36/91 (39%), Gaps = 16/91 (17%) Query: 386 PAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEK---------IYYITAD 436 P E ++ +AKL R +++ S +D V+R+K +E + Y+ Sbjct: 228 PRELSEVRQHLAKLARESASTLQSL--WTRAQDEVARLKALEELASGRFGFALLGYVPVK 285 Query: 437 SYAAAKSSPHLELLRKKGIEVLLLSDRIDEW 467 + + E L + V+ + +DE Sbjct: 286 AKPKVE-----EALARHKESVVYAFEPVDEH 311 >2R5J-A nrPDB Length = 423 Score = 30.4 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 19/42 (45%), Gaps = 6/42 (14%) Query: 413 TVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKG 454 VS ++YV+R IYY S A P+ ++K+ Sbjct: 2 VVSTDEYVTR-----TNIYYHAGSSRLLAVGHPYY-AIKKQD 37 >1D4E-A nrPDB Length = 572 Score = 30.0 bits (66), Expect = 3.1, Method: Composition-based stats. Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 9/113 (7%) Query: 424 KEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSV 483 +EG + IT A+A +L++KG E L D+ + L +G ++ Sbjct: 390 REGNRFMNEITTRDKASAA------ILQQKG-ESAYLV--FDDSIRKSLKAIEGYVHLNI 440 Query: 484 SKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTP 536 K +++E+LA ++D A E K +T + VK+ + + L L P Sbjct: 441 VKEGKTIEELAKQIDVPAAELAKTVTAYNGFVKSGKDAQFERPDLPRELVVAP 493 >1MX0-A nrPDB Length = 472 Score = 29.2 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 10/70 (14%) Query: 32 LRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDK-RTLTISDNGVGMTRDEV 90 +RELI N+ DA ++ + ++ + + D + + + DNG+G+ EV Sbjct: 38 VRELIENSLDA---------TDVHGILPNIKITIDLIDDARQIYKVNVVDNGIGIPPQEV 88 Query: 91 IDHLGTIAKS 100 + G + S Sbjct: 89 PNAFGRVLYS 98 >3FHO-A nrPDB Length = 508 Score = 29.2 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 19/34 (55%) Query: 223 SWEKINKAQALWTRNKSEITDEEYKEFYKHIAHD 256 SWE++N Q + R + + ++Y+E K + + Sbjct: 472 SWEEMNAIQEYFQRPITRVPTDDYEELEKVVKNA 505 >1Q78-A nrPDB Length = 514 Score = 29.2 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 25/55 (45%), Gaps = 8/55 (14%) Query: 280 IPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV 334 + + P+ ++ + + +R+ I+ + + +R + +S +LP +V Sbjct: 43 VETLKPFGVFEEEEE-----LQRRILILGKLNNLVKEW---IREISESKNLPQSV 89 >2ZBK-B nrPDB Length = 530 Score = 28.9 bits (63), Expect = 6.8, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 10/70 (14%) Query: 32 LRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDK-RTLTISDNGVGMTRDEV 90 +RELI N+ DA ++ + ++ + + D + + + DNG+G+ EV Sbjct: 36 VRELIENSLDA---------TDVHGILPNIKITIDLIDDARQIYKVNVVDNGIGIPPQEV 86 Query: 91 IDHLGTIAKS 100 + G + S Sbjct: 87 PNAFGRVLYS 96 >5JUT-YA nrPDB Length = 255 Score = 28.9 bits (63), Expect = 7.7, Method: Composition-based stats. Identities = 32/209 (15%), Positives = 73/209 (34%), Gaps = 12/209 (5%) Query: 333 NVSREILQDSTVTRNLRNALTKRVLQM-LEKLAKDDAEKYQTFW----QQFGLVLKEGPA 387 NV + ++ ST ++ +AL RV+++ L L + ++ + G L Sbjct: 42 NVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTNFH 101 Query: 388 EDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHL 447 + + ++R T +++ + +DYV R+ + S H+ Sbjct: 102 GMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHI 161 Query: 448 ELLRKKGIEVLLLSDRIDEWMMNYL-----TEFDGKPFQSVSKVDESLEKLADEVDESAK 502 +RK E+L + + + L E K ++ +K L+ + + K Sbjct: 162 RAIRKVISEIL--TKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLK 219 Query: 503 EAEKALTPFIDRVKALLGERVKDVRLTHR 531 + + + + GE + Sbjct: 220 QPKFDVGALMALHGEGSGEEKGKKVTGFK 248 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.136 0.353 Lambda K H 0.267 0.0413 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,736,145 Number of Sequences: 36641 Number of extensions: 911779 Number of successful extensions: 3416 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 85 Number of HSP's successfully gapped in prelim test: 43 Number of HSP's that attempted gapping in prelim test: 3047 Number of HSP's gapped (non-prelim): 145 length of query: 624 length of database: 10,336,785 effective HSP length: 103 effective length of query: 521 effective length of database: 6,562,762 effective search space: 3419199002 effective search space used: 3419199002 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.5 bits)