BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09960 (611 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5FWQ-A nrPDB 1274 0.0 4GAA-A nrPDB 908 0.0 2XPY-A nrPDB 434 e-122 3CIA-A nrPDB 375 e-104 5C97-A nrPDB 114 1e-25 5DLL-A nrPDB 108 8e-24 1Z1W-A nrPDB 103 2e-22 5LHD-A nrPDB 100 2e-21 5LG6-A nrPDB 99 5e-21 4KXA-A nrPDB 89 7e-18 3QNF-A nrPDB 87 3e-17 4WZ9-A nrPDB 86 6e-17 5Y1X-A nrPDB 82 9e-16 4Q4I-A nrPDB 82 9e-16 3SE6-A nrPDB 80 2e-15 4QHP-A nrPDB 75 7e-14 5ZI5-A nrPDB 44 2e-04 4PD2-A nrPDB 31 1.8 6EM8-A nrPDB 30 2.2 2R2P-A nrPDB 28 8.4 >5FWQ-A nrPDB Length = 633 Score = 1274 bits (3297), Expect = 0.0, Method: Compositional matrix adjust. Identities = 611/611 (100%), Positives = 611/611 (100%) Query: 1 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL 60 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL Sbjct: 15 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL 74 Query: 61 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT 120 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT Sbjct: 75 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT 134 Query: 121 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP 180 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP Sbjct: 135 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP 194 Query: 181 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES 240 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES Sbjct: 195 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES 254 Query: 241 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH 300 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH Sbjct: 255 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH 314 Query: 301 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET 360 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET Sbjct: 315 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET 374 Query: 361 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI 420 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI Sbjct: 375 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI 434 Query: 421 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK 480 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK Sbjct: 435 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK 494 Query: 481 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL 540 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL Sbjct: 495 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL 554 Query: 541 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT 600 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT Sbjct: 555 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT 614 Query: 601 AMLVGKDLKVD 611 AMLVGKDLKVD Sbjct: 615 AMLVGKDLKVD 625 >4GAA-A nrPDB Length = 609 Score = 908 bits (2347), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/607 (67%), Positives = 505/607 (83%), Gaps = 1/607 (0%) Query: 4 IVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIE 63 + D S ASP KH+HL+ VDFT R + + +LTV+S +D+L SL+LDTKDLTI+ Sbjct: 1 MADPSSFASPEKF-NIKHMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIK 59 Query: 64 KVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQ 123 KV +NG++ +ALG S+KG+P+EI+LP +L++ QE+++EI TSPKSSALQWL EQ Sbjct: 60 KVAVNGKDATFALGTTHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLNKEQ 119 Query: 124 TSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPE 183 T+GK HPYLFSQCQA HCR+I+PCQDTPSVK TY ++VSVPKEL+ALMSA+RDGE + Sbjct: 120 TAGKIHPYLFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMALMSALRDGELSEQS 179 Query: 184 DPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLK 243 D +RKIY+F Q VPIP YLIALVVGALE R++GPRT +W+EKE +E S YEF+ETE MLK Sbjct: 180 DSNRKIYRFKQNVPIPSYLIALVVGALEGRKVGPRTTIWTEKELLEPSVYEFAETEKMLK 239 Query: 244 IAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWT 303 AEDL GPYVWGQYDLL+LPPSFPYGGMENPCLTFVTPT+LAGD+SL++VIAHEISHSWT Sbjct: 240 YAEDLAGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLASVIAHEISHSWT 299 Query: 304 GNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPF 363 GNLVTN+TW++FWLNEGHTVYLER I GRL+GE+FR F ALGGW ELQNSV TFG T+P Sbjct: 300 GNLVTNETWENFWLNEGHTVYLERRIDGRLYGEEFRQFKALGGWKELQNSVNTFGATNPL 359 Query: 364 TKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTD 423 T LV +L ++D D A+SSVPYEKGFALLFYLEQLLGGPEIFLGFLK+Y++ F++KS+TT+ Sbjct: 360 TNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAFKSVTTE 419 Query: 424 DWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDD 483 +WK FLYSYFKDKVD+L++VDW W+++PG+PP++P YDMTL NACI L Q+W+ A E D Sbjct: 420 EWKKFLYSYFKDKVDILDKVDWKGWMHTPGMPPVQPKYDMTLANACITLGQKWVKATESD 479 Query: 484 LNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLC 543 L SF+A D+KDLSSHQL E LA L PLP+ H+KRMQEVYN N + NSEIRFRWLRLC Sbjct: 480 LGSFSADDVKDLSSHQLIEVLAILLLEKPLPVSHVKRMQEVYNLNDVKNSEIRFRWLRLC 539 Query: 544 IQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAML 603 I++ WED IPLAL MATEQGRMKFTRPL++DL F+K+ +Q V T+ ++++ MHPVT ML Sbjct: 540 IRAGWEDVIPLALAMATEQGRMKFTRPLYRDLYNFEKAREQTVNTFLKNRSFMHPVTEML 599 Query: 604 VGKDLKV 610 V KDL + Sbjct: 600 VAKDLHI 606 >2XPY-A nrPDB Length = 632 Score = 434 bits (1117), Expect = e-122, Method: Compositional matrix adjust. Identities = 248/615 (40%), Positives = 364/615 (59%), Gaps = 43/615 (6%) Query: 21 HLHLRCSVDFTRRTLTGTAALTVQS-QEDNLRS--LVLDTKDLTIEKVVINGQEVKYALG 77 H L SV F + ++G+ ++ E +S L LDT L +++V I+G + + + Sbjct: 32 HTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQIE 91 Query: 78 ERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQ 137 +R+ GS + I+ S N + I F T+ K +ALQWL +QT G + PY+FSQ + Sbjct: 92 QRKEPLGSRLVIN---NASCNDNFTLNIQFRTTDKCTALQWLNSKQTKGGK-PYVFSQLE 147 Query: 138 AIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSR--KIYKFIQK 195 AIH R++ PC DTPSVK T+TA + P L + S IR ED S+ IY+F QK Sbjct: 148 AIHARSLFPCFDTPSVKSTFTASIESP--LPVVFSGIR------IEDTSKDTNIYRFEQK 199 Query: 196 VPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEF-SETESMLKIAEDLGGPYVW 254 VPIP YLI + G L S IGPR+ V++E +++ +EF ++ E ++ AE + Y W Sbjct: 200 VPIPAYLIGIASGDLSSAPIGPRSTVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEW 259 Query: 255 GQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDH 314 G YD+LV S+PYGGME+P +TF TPTL+A D+S +VIAHE++HSW+GNLVTN +W+H Sbjct: 260 GTYDILVNVDSYPYGGMESPNMTFATPTLIAHDRSNIDVIAHELAHSWSGNLVTNCSWNH 319 Query: 315 FWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTD-I 373 FWLNEG TVYLER I G + GE RHF+AL GW +LQNS+ + + F+ LV +L D Sbjct: 320 FWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNSIDSMKDPERFSTLVQNLNDNT 379 Query: 374 DPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYF 433 DPD A+S+VPYEKGF LLF+LE +LGG F F++ Y +KF+ KS+ T + D LY ++ Sbjct: 380 DPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLDTFQFLDTLYEFY 439 Query: 434 KDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWI------TAKEDDLNSF 487 +K ++L+ VDW WLY PG+PP +P++ L + L+ +W+ ED + F Sbjct: 440 PEKKEILDSVDWETWLYKPGMPP-RPHFITALADNVYQLADKWVEMAQHLKTTEDFRSEF 498 Query: 488 NATDLKDLSSHQLNEFLAQTLQR------------APLPLGHIKRMQEVYNFNAI--NNS 533 NA D+KD +S+QL FL Q A P+ + + ++Y N + N+ Sbjct: 499 NAIDIKDFNSNQLVLFLETLTQNGHSNKKPKDFDWAKFPVAS-RALLDIYQDNIVKSQNA 557 Query: 534 EIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHK 593 E+ F+ + I +K ++ GRMKF RP ++ L + D+ A+ T+ + K Sbjct: 558 EVVFKMFKFQIFAKLQEEYKHLADWLGTVGRMKFVRPGYRLLNSVDRR--LALATFDKFK 615 Query: 594 ASMHPVTAMLVGKDL 608 + HP+ LV +DL Sbjct: 616 DTYHPICKALVKQDL 630 >3CIA-A nrPDB Length = 605 Score = 375 bits (963), Expect = e-104, Method: Compositional matrix adjust. Identities = 221/603 (36%), Positives = 344/603 (57%), Gaps = 33/603 (5%) Query: 17 CRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVI---NGQEVK 73 + H++L +VDF +++L+G A L++ DN L+LDT+DL I +V+ GQ VK Sbjct: 26 VKATHVYLDLNVDFDKKSLSGFAELSLDWFTDNKAPLILDTRDLVIHRVMAKNSQGQWVK 85 Query: 74 --YALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPY 131 Y L +R GS + I+ P+ K + + + ++ K++ LQWL+ EQT+GKE P+ Sbjct: 86 VNYDLAKRDDVLGSKLTINTPLNAKK-----VRVYYNSTEKATGLQWLSAEQTAGKEKPF 140 Query: 132 LFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYK 191 LFSQ QAIH R+ +P QDTPSV++TYTA ++ K+L+A+MSA + T D Y Sbjct: 141 LFSQNQAIHARSWIPIQDTPSVRVTYTARITTDKDLLAVMSANNEPGTERDGD-----YF 195 Query: 192 FIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGP 251 F IP YLIA+ VG LE + + +T +++E ++ + EF +T++M+ AE + G Sbjct: 196 FSMPQAIPPYLIAIGVGDLEFKAMSHQTGIYAESYILDAAVAEFDDTQAMIDKAEQMYGK 255 Query: 252 YVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKT 311 Y WG+YDLL+LPPSFP+GGMENP L+F+TPT++AGDKSL N+IAHE++HSW+GNLVTN++ Sbjct: 256 YRWGRYDLLMLPPSFPFGGMENPRLSFITPTVVAGDKSLVNLIAHELAHSWSGNLVTNES 315 Query: 312 WDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLT 371 W WLNEG T Y+E I +FG G +L + + T+L +DL Sbjct: 316 WRDLWLNEGFTSYVENRIMEAVFGTDRAVMEQALGAQDLNAEILELDASD--TQLYIDLK 373 Query: 372 DIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYS 431 DPD A+S VPY KG L YLE+ G E F F+ Y + +++S+ TD++ +L + Sbjct: 374 GRDPDDAFSGVPYVKGQLFLMYLEEKF-GRERFDAFVLEYFDSHAFQSLGTDNFVKYLKA 432 Query: 432 YFKDKV-DVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNAT 490 DK ++++ + N W++ GLP P +NA + ++ D+L Sbjct: 433 NLTDKYPNIVSDNEINEWIFKAGLPSYAPQ---PTSNAFKVIDKQINQLVTDELT----- 484 Query: 491 DLKDLSSHQ--LNEFLAQTLQRAPLPLGHIK--RMQEVYNFNAINNSEIRFRWLRLCIQS 546 L+ L + Q L+E+L + P+ L H + + + ++ +N+EI W L +++ Sbjct: 485 -LEQLPTAQWTLHEWL-HFINNLPVDLDHQRMVNLDKAFDLTNSSNAEIAHAWYLLSVRA 542 Query: 547 KWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGK 606 +++ P K GR K PL+K+LA +S AV Y++ + H + V Sbjct: 543 DYKEVYPAMAKYLKSIGRRKLIVPLYKELAKNAESKAWAVEVYKQARPGYHGLAQGTVDG 602 Query: 607 DLK 609 LK Sbjct: 603 VLK 605 >5C97-A nrPDB Length = 912 Score = 114 bits (286), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 119/474 (25%), Positives = 207/474 (43%), Gaps = 52/474 (10%) Query: 13 PASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKV----VIN 68 P +V ++ L + T T G+ ++VQ+ + +++L + I +V ++ Sbjct: 46 PTAVVPLRY-ELSLHPNLTSMTFRGSVTISVQALQVTW-NIILHSTGHNISRVTFMSAVS 103 Query: 69 GQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQT--SG 126 QE + + E +Y G + I P AL ++I + + SS + T S Sbjct: 104 SQEKQAEILEY-AYHGQ-IAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESN 161 Query: 127 KEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMS-------AIRDGET 179 ++ + +Q + + R+ PC D P+ K T+ ++ ++ AL + + DG Sbjct: 162 EKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLV 221 Query: 180 PDPEDPSRKIYKFIQKVPIPCYLIALVVGALE--SRQI-GPRTLVWSEKEQVEKSAYEFS 236 D +F + V + YL+A +VG ++ S+ + G +++ E++ + Y Sbjct: 222 QD---------EFSESVKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALE 272 Query: 237 ETESMLKIAEDLGGPYVWGQYDL----LVLPPSFPYGGMEN-PCLTFVTPTLL------- 284 T +L+ ++ Y QY L LV P F G MEN LTF TLL Sbjct: 273 TTVKLLEFFQN----YFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSS 328 Query: 285 -AGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNA 343 A K ++ +IAHE++H W GNLVT K W+ WLNEG ++E ++F E + + Sbjct: 329 MADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDF 388 Query: 344 LGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEI 403 L + + +HP + V I+ + S+ Y KG +LL L+ L ++ Sbjct: 389 LDARFKTMKK-DSLNSSHPISSSVQSSEQIEE--MFDSLSYFKGSSLLLMLKTYL-SEDV 444 Query: 404 FLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPI 457 F + Y+ SY SI +DD D +DV + W G P + Sbjct: 445 FQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQTLDVKRMM--KTWTLQKGFPLV 496 >5DLL-A nrPDB Length = 867 Score = 108 bits (269), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 121/492 (24%), Positives = 204/492 (41%), Gaps = 84/492 (17%) Query: 23 HLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSY 82 HL +D ++ +T + + +LVLD +L + + +N + + Sbjct: 32 HLIFELDESKTRVTANLYIVANRENRENNTLVLDGVELKLLSIKLNNKHL---------- 81 Query: 83 KGSPMEISLPIALSKNQEIVIEISFETSPKSSALQW---LTPEQTSGKEHPY----LFS- 134 SP E A+++NQ I+ + P+ LQ + P + E Y +FS Sbjct: 82 --SPAEF----AVNENQLIINNV-----PEKFVLQTVVEINPSANTSLEGLYKSGDVFST 130 Query: 135 QCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQ 194 QC+A R I D P V +T ++ K+ ++ + +G+ D D S + + Sbjct: 131 QCEATGFRKITYYLDRPDVMAAFTVKIIADKKKYPII--LSNGDKIDSGDISDNQHFAVW 188 Query: 195 KVPI--PCYLIALVVGALES--------RQIGPRTLVWSEKEQVEKSAYEFSETESMLKI 244 K P PCYL ALV G L S Q +++ K+ ++K Y + +K Sbjct: 189 KDPFKKPCYLFALVAGDLASIKDTYITKSQRKVSLEIYAFKQDIDKCHYAMQAVKDSMKW 248 Query: 245 AEDLGGPYVWGQYDL----LVLPPSFPYGGMENPCLT-FVTPTLLAGDKSLSN------- 292 ED G +YDL +V P F G MEN L F T ++A +K+ ++ Sbjct: 249 DEDRFGL----EYDLDTFMIVAVPDFNAGAMENKGLNIFNTKYIMASNKTATDKDFELVQ 304 Query: 293 -VIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQ 351 V+ HE H+WTG+ VT + W L EG TV+ ++ L + + + + Sbjct: 305 SVVGHEYFHNWTGDRVTCRDWFQLSLKEGLTVFRDQEFTSDLNSRDVKRIDDV----RII 360 Query: 352 NSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAY 411 S + + P + + + I+ + Y+ Y KG ++ + LL G E F +K Y Sbjct: 361 RSAQFAEDASPMSHPIRPESYIEMNNFYTVTVYNKGAEIIRMIHTLL-GEEGFQKGMKLY 419 Query: 412 VEKFSYKSITTDDWKDFL-------YSYFKDKVDVLNQVDWNAWLYSPGLPPIK--PNYD 462 E+ +++T DD+ + + +S FK W G P IK NYD Sbjct: 420 FERHDGQAVTCDDFVNAMADANNRDFSLFK------------RWYAQSGTPNIKVSENYD 467 Query: 463 MTLTNACIALSQ 474 + + L Q Sbjct: 468 ASSQTYSLTLEQ 479 >1Z1W-A nrPDB Length = 780 Score = 103 bits (258), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 115/455 (25%), Positives = 188/455 (41%), Gaps = 62/455 (13%) Query: 24 LRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYK 83 L D +RT GT +T + + +VLD L I + +NG++ + +Y Sbjct: 8 LTLDFDIQKRTFNGTETITADAGD-----IVLDAVGLQINWMKVNGRDTAF------TYD 56 Query: 84 GSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRA 143 G + A +Q IEISF S L+ +G+E+ + + +A R Sbjct: 57 GQTVR-----APGDSQPQKIEISFAGKVSDS----LSGIYYAGRENGMITTHFEATDARR 107 Query: 144 ILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLI 203 + PC D P+ K + V + K+ AI + E RK+ +F + YL+ Sbjct: 108 MFPCVDHPAYKAVFAITVVIDKDY----DAISNMPPKRIEVSERKVVEFQDTPRMSTYLL 163 Query: 204 ALVVGAL--ESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAED-LGGPYVWGQYDLL 260 + +G E + L+ + + + +S Y ++ E+ G PY + L+ Sbjct: 164 YVGIGKFRYEYEKYRDIDLILASLKDI-RSKYPLDMARKSVEFYENYFGIPYALPKMHLI 222 Query: 261 VLPPSFPYGGMEN-PCLTF-------VTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTW 312 +P F G MEN +TF + + ++ +NVIAHEI+H W G+LVT K W Sbjct: 223 SVP-EFGAGAMENWGAITFREIYMDIAENSAVTVKRNSANVIAHEIAHQWFGDLVTMKWW 281 Query: 313 DHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFG--------ETHPFT 364 + WLNE ++ LF E WG+ S +T G THP Sbjct: 282 NDLWLNESFATFMSYKTMDTLFPE-------WSFWGDFFVS-RTSGALRSDSLKNTHP-- 331 Query: 365 KLVVDLTDIDP-DVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTD 423 + VD+ D D + + Y KG ++L +E G E G K Y+ + + Sbjct: 332 -IEVDVRDPDEISQIFDEISYGKGASILRMIEDYAGYEEFRKGISK-YLNDHKFGNAEGS 389 Query: 424 DWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIK 458 D L++ +D + W+ +PG P IK Sbjct: 390 D----LWTAIEDVSGKPVKRVMEYWIKNPGYPVIK 420 >5LHD-A nrPDB Length = 950 Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 85/306 (27%), Positives = 139/306 (45%), Gaps = 24/306 (7%) Query: 134 SQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDG-ETPDPEDPSRKIYKF 192 +Q QA R PC D P++K + + PK+L AL + + G TP PEDP+ + +F Sbjct: 193 TQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEF 252 Query: 193 IQKVPIPCYLIALVVGALE--SRQIGPRTLV--WSEKEQVEKSA--YEFSETESMLKI-A 245 + YL+A +V + +Q L+ W+ + Y + T +L A Sbjct: 253 HTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFA 312 Query: 246 EDLGGPYVWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLL--------AGDKSLSNVIAH 296 PY + D + LP F G MEN L T+ +LL + + + VIAH Sbjct: 313 GHYDTPYPLPKSDQIGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAH 371 Query: 297 EISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQN--SV 354 E++H W GNLVT + W+ WLNEG Y+E G + E + L ++ +V Sbjct: 372 ELAHQWFGNLVTIEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLNDVYRVMAV 429 Query: 355 KTFGETHPFTKLVVDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVE 413 +HP + ++ T + ++ Y KG ++L L L ++F L +Y+ Sbjct: 430 DALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFL-SEDVFKQGLASYLH 488 Query: 414 KFSYKS 419 F+Y++ Sbjct: 489 TFAYQN 494 >5LG6-A nrPDB Length = 968 Score = 99.0 bits (245), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 92/326 (28%), Positives = 141/326 (43%), Gaps = 28/326 (8%) Query: 134 SQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGE-TPDPEDPSRKIYKF 192 +Q Q+ R PC D P++K T+ + P L AL + G TP EDP+ + +F Sbjct: 187 TQMQSTDARKSFPCFDEPAMKATFNITLIHPNNLTALSNMPPKGSSTPLAEDPNWSVTEF 246 Query: 193 IQKVPIPCYLIALVVGAL----ESRQIGPRTLVWSEKEQVEKS--AYEFSETESMLKI-A 245 + YL+A +V E+ Q G +W+ + + Y + T +L A Sbjct: 247 ETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIWARPNAIAEGHGMYALNVTGPILNFFA 306 Query: 246 EDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGD---KSLSN------VIAH 296 Y + D + LP F G MEN L L D S+SN VIAH Sbjct: 307 NHYNTSYPLPKSDQIALP-DFNAGAMENWGLVTYRENALLFDPQSSSISNKERVVTVIAH 365 Query: 297 EISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQN--SV 354 E++H W GNLVT W+ WLNEG Y+E G E + L G++ +V Sbjct: 366 ELAHQWFGNLVTLAWWNDLWLNEGFASYVE--YLGADHAEPTWNLKDLIVPGDVYRVMAV 423 Query: 355 KTFGETHPFTKLVVDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVE 413 +HP T ++ T + S+ Y KG +++ L L ++F L +Y+ Sbjct: 424 DALASSHPLTTPAEEVNTPAQISEMFDSISYSKGASVIRMLSNFL-TEDLFKEGLASYLH 482 Query: 414 KFSYKSITTDDWKDFLYSYFKDKVDV 439 F+Y++ T D L+ + + VD Sbjct: 483 AFAYQNTTYLD----LWEHLQKAVDA 504 >4KXA-A nrPDB Length = 888 Score = 88.6 bits (218), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 83/302 (27%), Positives = 137/302 (45%), Gaps = 28/302 (9%) Query: 141 CRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPC 200 R PC D P+ K TYT ++ PKE AL + E + +R ++ + VP+ Sbjct: 152 ARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFE--KSVPMST 209 Query: 201 YLIALVVGALES-RQI---GPRTLVWSEKEQVEKSAYEFSETESMLKIAED-LGGPYVWG 255 YL+ V +S ++I G ++ + EQ + Y + T+S+ E+ Y Sbjct: 210 YLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLP 269 Query: 256 QYDLLVLPPSFPYGGMEN-PCLTFVTPTLL--------AGDKSLSNVIAHEISHSWTGNL 306 + D + +P F G MEN +T+ LL + + ++ V+AHE+ H W GN+ Sbjct: 270 KLDKIAIP-DFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNI 328 Query: 307 VTNKTWDHFWLNEGHTVYLERHICGRLFGE---KFRHFNALGGWGELQNSVKTFGETHPF 363 VT W+ WLNEG + E G E + R L +Q + +HP Sbjct: 329 VTMDWWEDLWLNEGFASFFE--FLGVNHAETDWQMRDQMLLEDVLPVQED-DSLMSSHP- 384 Query: 364 TKLVVDLTDIDPDVA-YSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITT 422 ++V +T D + + + Y KG ++L LE + PE F + Y+EK+ +K+ T Sbjct: 385 --IIVTVTTPDEITSVFDGISYSKGSSILRMLEDWI-KPENFQKGCQMYLEKYQFKNAKT 441 Query: 423 DD 424 D Sbjct: 442 SD 443 >3QNF-A nrPDB Length = 954 Score = 86.7 bits (213), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 82/326 (25%), Positives = 141/326 (43%), Gaps = 49/326 (15%) Query: 134 SQCQAIHCRAILPCQDTPSVKLTYTAEVSV-PKEL-VALMSAIRDGETPDP--EDPSRKI 189 +Q + R PC D P+ K +++ ++ P+ L ++ M ++ + ED Sbjct: 186 TQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED----- 240 Query: 190 YKFIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIA 245 F V + YL+A ++ ES + G + V++ +++ ++ Y ++L+ Sbjct: 241 -HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFY 299 Query: 246 ED-LGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNV---------IA 295 ED PY + DL +P F G MEN LT + L D S+ +A Sbjct: 300 EDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVA 358 Query: 296 HEISHSWTGNLVTNKTWDHFWLNEGHTVYL----------ERHICGRLFGEKFRHFNALG 345 HE++H W GNLVT + W+ WLNEG ++ E + FG + F+A+ Sbjct: 359 HELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFG---KCFDAM- 414 Query: 346 GWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFL 405 V +HP + V + I + V Y+KG +L L + L Sbjct: 415 -------EVDALNSSHPVSTPVENPAQIRE--MFDDVSYDKGACILNMLREYLSADAFKS 465 Query: 406 GFLKAYVEKFSYKSITTDDWKDFLYS 431 G ++ Y++K SYK+ +D D + S Sbjct: 466 GIVQ-YLQKHSYKNTKNEDLWDSMAS 490 >4WZ9-A nrPDB Length = 957 Score = 85.5 bits (210), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 87/329 (26%), Positives = 143/329 (43%), Gaps = 32/329 (9%) Query: 22 LHLRCSVDFTRRTLTGTAALTVQ--SQEDNL----RSLVLDTKDLTIEKVVINGQEVKYA 75 LHLR + RT TGT + +Q D L R LV+ + ++ + G Sbjct: 59 LHLRTEIHRNERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKVSSLPNGVTGAPT--L 116 Query: 76 LGERQSYKGSPME---ISLPIALSKNQEIVIEISFETSPKSSALQ-WLTPEQTSGKEHPY 131 +G+ Q + E + P L ++E++F+ ++ +++ E Y Sbjct: 117 IGDVQYSTDTTFEHITFTSPTILQPGT-YLLEVAFQGRLATNDDGFYVSSYVADNGERRY 175 Query: 132 LFS-QCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIY 190 L + Q ++ R PC D P +K T+T ++ A+ S + T D E R Sbjct: 176 LATTQFESTSARMAFPCYDEPGLKATFTVSITHSLSYKAI-SNMPQKTTTDIETDMRT-- 232 Query: 191 KFIQKVP-IPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAED-L 248 F +K P + YL+A VV + R G + V+ ++ + +LK+ +D L Sbjct: 233 TFFEKTPAMSTYLLAFVVSDFQLRLSGAQR-VYVRPNAFNEATFALEAGVKILKVLDDHL 291 Query: 249 GGPY--VWGQYDLLVLPPSFPYGGMEN-PCLTFVTPTLL--------AGDKSLSNVIAHE 297 G PY + D + +P F G MEN +T+ LL G +++ IAHE Sbjct: 292 GIPYDTYMPKLDQIAIP-DFAAGAMENWGLVTYREQALLFNPAVSTYRGKTNVATTIAHE 350 Query: 298 ISHSWTGNLVTNKTWDHFWLNEGHTVYLE 326 +H W GNLV+ + W++ WLNEG E Sbjct: 351 YAHQWFGNLVSPEWWEYIWLNEGFATLYE 379 >5Y1X-A nrPDB Length = 914 Score = 81.6 bits (200), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 123/461 (26%), Positives = 190/461 (41%), Gaps = 70/461 (15%) Query: 53 LVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEI-SLPIALSK---NQEIVIEISFE 108 LV D L I ++ IN + K GE +Y + I S + SK + E++I Sbjct: 73 LVFDGVGLKINEISINNK--KLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIH---- 126 Query: 109 TSPKSS-ALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKE- 166 P+++ AL L K + SQC+A R I D P + Y V+ KE Sbjct: 127 --PETNYALTGLY------KSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEK 178 Query: 167 ---LVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWS 223 L++ + + E P +R F PCYL A+V G L + + + Sbjct: 179 YPVLLSNGDKVNEFEIPGGRHGAR----FNDPHLKPCYLFAVVAGDL--KHLSATYITKY 232 Query: 224 EKEQVEKSAYEFSETESM---------LKIAEDLGGPYVWGQYDL----LVLPPSFPYGG 270 K++VE Y FSE + + LK + Y +YDL LV F G Sbjct: 233 TKKKVE--LYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGA 290 Query: 271 MENPCLT-FVTPTLLAGDKS--------LSNVIAHEISHSWTGNLVTNKTWDHFWLNEGH 321 MEN L F +LLA K+ + V+ HE H++TGN VT + W L EG Sbjct: 291 MENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGL 350 Query: 322 TVYLERHICGRLFGEKF-RHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYS 380 TV+ E LF E+ + +L SV+ ++ P + + + + + Y+ Sbjct: 351 TVHRE-----NLFSEEMTKTVTTRLSHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYT 405 Query: 381 SVPYEKGFALL-FYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFK----D 435 + Y+KG ++ YL L G E + Y++K + T +D+ + +K D Sbjct: 406 TTVYDKGSEVMRMYLTIL--GEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKAD 463 Query: 436 KVDVLNQVDWNAWLYSPGLPPI--KPNYDMTLTNACIALSQ 474 LNQ + W G P + K NYD I ++Q Sbjct: 464 NSANLNQ--YLLWFSQSGTPHVSFKYNYDAEKKQYSIHVNQ 502 >4Q4I-A nrPDB Length = 891 Score = 81.6 bits (200), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 92/377 (24%), Positives = 154/377 (40%), Gaps = 57/377 (15%) Query: 132 LFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKE----LVALMSAIRDGETPDPEDPSR 187 L +QC+A R I D P V +T ++ K L++ + + GE + R Sbjct: 137 LCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQGELEN----GR 192 Query: 188 KIYKFIQKVPIPCYLIALVVGALE----------SRQIGPRTLVWSEKEQVEKSAYEFSE 237 ++ P PCYL ALV G + R++ ++ ++ ++++ + + Sbjct: 193 HWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALE--LYVDRGNLDRAPWAMTS 250 Query: 238 TESMLKIAEDLGGPYVWGQYDL----LVLPPSFPYGGMENPCLTF------VTPTLLAGD 287 ++ +K E+ G +YDL +V F G MEN L + T A D Sbjct: 251 LKNSMKWDEERFGL----EYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATD 306 Query: 288 KS---LSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNAL 344 K + VI HE H+WTGN VT + W L EG TV+ ++ L N + Sbjct: 307 KDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNV 366 Query: 345 GGWGELQNSVKTFGETHPFT-KLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEI 403 LQ + HP +V+++ + Y+ YEKG ++ + LL G E Sbjct: 367 RTMRGLQFAEDASPMAHPIRPDMVIEMNNF-----YTLTVYEKGAEVIRMIHTLL-GEEN 420 Query: 404 FLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVD---WNAWLYSPGLP--PIK 458 F ++ Y E+ + T DD F ++ + VD + W G P +K Sbjct: 421 FQKGMQLYFERHDGSAATCDD--------FVQAMEDASNVDLSHFRRWYSQSGTPIVTVK 472 Query: 459 PNYDMTLTNACIALSQR 475 +Y+ + +SQR Sbjct: 473 DDYNPETEQYTLTISQR 489 >3SE6-A nrPDB Length = 967 Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 80/299 (26%), Positives = 131/299 (43%), Gaps = 21/299 (7%) Query: 140 HCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIP 199 R PC D P K ++ ++ +AL S + +T + E + + F V + Sbjct: 203 QARMAFPCFDEPLFKANFSIKIRRESRHIAL-SNMPKVKTIELEGGLLEDH-FETTVKMS 260 Query: 200 CYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYV-W 254 YL+A +V S G + +++ ++ ++ Y + +L E Y Sbjct: 261 TYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPL 320 Query: 255 GQYDLLVLPPSFPYGGMEN-PCLTFVTPTLL-------AGDKS-LSNVIAHEISHSWTGN 305 + DL+ +P F G MEN +T+ +LL A DK ++ VIAHE++H W GN Sbjct: 321 SKLDLIAIP-DFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGN 379 Query: 306 LVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTK 365 LVT + W+ WLNEG Y+E + E L E+ + + P +K Sbjct: 380 LVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITK-DSLNSSRPISK 438 Query: 366 LVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDD 424 T I + V Y KG +L L+ LG + G ++ Y++KFSY++ DD Sbjct: 439 PAETPTQIQE--MFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ-YLKKFSYRNAKNDD 494 >4QHP-A nrPDB Length = 870 Score = 75.1 bits (183), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 106/412 (25%), Positives = 161/412 (39%), Gaps = 57/412 (13%) Query: 41 LTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYAL-GERQSYKGSPMEISLPIALSKNQ 99 LTV+ Q LVLD + V ING Y L GE + G P E Sbjct: 41 LTVEPQRVG-EPLVLDGS-AKLLSVKINGAAADYVLEGETLTIAGVPSE----------- 87 Query: 100 EIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTA 159 +E+ E P + + L SG LF+QC+ R I D P V +T Sbjct: 88 RFTVEVETEILPAEN--KSLMGLYASGGN---LFTQCEPEGFRKITFYIDRPDVMSKFTT 142 Query: 160 EVSVPKE----LVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQ- 214 + K+ L++ + I GE D R K+ P YL ALV G L + Sbjct: 143 TIVADKKRYPVLLSNGNKIDGGEFSD----GRHWVKWEDPFSKPSYLFALVAGDLAVTED 198 Query: 215 ----IGPRTL---VWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDL----LVLP 263 + R + ++ + K + ++ +K E G +YDL +V Sbjct: 199 YFTTMSGRNVKIEFYTTEADKPKVGFAVESLKNAMKWDETRFGL----EYDLDIFMVVAV 254 Query: 264 PSFPYGGMENPCLT-FVTPTLLAGDKS--------LSNVIAHEISHSWTGNLVTNKTWDH 314 F G MEN L F T +LA ++ + +V+ HE H+WTGN VT + W Sbjct: 255 GDFNMGAMENKGLNIFNTKFVLADSRTATDTDFEGIESVVGHEYFHNWTGNRVTCRDWFQ 314 Query: 315 FWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDID 374 L EG TV+ ++ G R + + Q HP + + Sbjct: 315 LSLKEGLTVFRDQEFSGDRASRAVRRIENIRLLRQHQFPEDAGPTAHPVRPASYE----E 370 Query: 375 PDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWK 426 + Y+ YEKG ++ LL G E F +K Y ++ +++T DD++ Sbjct: 371 MNNFYTMTVYEKGAEVVRMYHTLL-GEEGFQKGMKLYFQRHDGQAVTCDDFR 421 >5ZI5-A nrPDB Length = 921 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 90/432 (20%), Positives = 166/432 (38%), Gaps = 65/432 (15%) Query: 22 LHLRCSVDFTRRTLTGTAALTVQ---SQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGE 78 +H+ +D +++ + A LTV + + + LVLD +++T+ + +N +K E Sbjct: 50 IHVDLQIDLSKKPVESKARLTVVPNLNVDSHSNDLVLDGENMTLVSLQMNDNLLKE--NE 107 Query: 79 RQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQA 138 + K S + ++P +N IE+ TS +T G + ++ Sbjct: 108 YELTKDSLIIKNIP----QNTPFTIEM---TSLLGENTDLFGLYETEG----VALVKAES 156 Query: 139 IHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYK--FIQKV 196 R + D P TY + +E ++ + +G + ++ ++ ++ V Sbjct: 157 EGLRRVFYLPDRPDNLATYKTTIIANQEDYPVL--LSNGVLIEKKELPLGLHSVTWLDDV 214 Query: 197 PIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEF----SETESMLKIAEDLGGPY 252 P P YL ALV G L+ R++ + + + + EF S T E L Sbjct: 215 PKPSYLFALVAGNLQ------RSVTYYQTKSGRELPIEFYVPPSATSKCDFAKEVLKEAM 268 Query: 253 VWGQYD----------LLVLPPSFPYGGMENPCLT-FVTPTLLAGDKSLSN--------V 293 W + ++ + G E L F T L A ++ ++ V Sbjct: 269 AWDERTFNLECALRQHMVAGVDKYASGASEPTGLNLFNTENLFASPETKTDLGILRVLEV 328 Query: 294 IAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNS 353 +AHE H W+G+ VT + W + L EG T + LFG L G Sbjct: 329 VAHEFFHYWSGDRVTIRDWFNLPLKEGLTTFRAAMFREELFGTDL--IRLLDG------- 379 Query: 354 VKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVE 413 K E P + + Y++ YEK A +F + L G E F+ + + + Sbjct: 380 -KNLDERAPRQSAYTAVRSL-----YTAAAYEKS-ADIFRMMMLFIGKEPFIEAVAKFFK 432 Query: 414 KFSYKSITTDDW 425 ++T +D+ Sbjct: 433 DNDGGAVTLEDF 444 >4PD2-A nrPDB Length = 272 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 13/85 (15%) Query: 282 TLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVY------LERHICGRLFG 335 TL+AG L N+ E+ W + K + + H ++ L++ I +L G Sbjct: 164 TLVAG---LGNIYVDEVL--WLAKIHPEKETNQLIESSIHLLHDSIIEILQKAI--KLGG 216 Query: 336 EKFRHFNALGGWGELQNSVKTFGET 360 R ++ALG G++QN ++ +G+T Sbjct: 217 SSIRTYSALGSTGKMQNELQVYGKT 241 >6EM8-A nrPDB Length = 818 Score = 30.4 bits (67), Expect = 2.2, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 2/42 (4%) Query: 47 EDNLRSLVLDTKDLTIEKVVI--NGQEVKYALGERQSYKGSP 86 EDNL L+LD + +KV + +G+E KY + E+ S +P Sbjct: 774 EDNLSELILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTP 815 >2R2P-A nrPDB Length = 295 Score = 28.5 bits (62), Expect = 8.4, Method: Compositional matrix adjust. Identities = 17/76 (22%), Positives = 36/76 (47%) Query: 183 EDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESML 242 EDP++ +++F +++ C I V+GA E ++ L K ++ + + Sbjct: 6 EDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEK 65 Query: 243 KIAEDLGGPYVWGQYD 258 + + LG + GQ+D Sbjct: 66 QRRDFLGEASIMGQFD 81 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FWQ-A nrPDB 879 0.0 4GAA-A nrPDB 814 0.0 2XPY-A nrPDB 634 0.0 3CIA-A nrPDB 604 e-173 5C97-A nrPDB 420 e-117 5DLL-A nrPDB 408 e-114 1Z1W-A nrPDB 396 e-110 4Q4I-A nrPDB 383 e-106 4QHP-A nrPDB 376 e-104 5LG6-A nrPDB 365 e-101 5Y1X-A nrPDB 359 2e-99 3QNF-A nrPDB 359 3e-99 5LHD-A nrPDB 357 7e-99 3SE6-A nrPDB 352 2e-97 4KXA-A nrPDB 341 7e-94 4WZ9-A nrPDB 339 2e-93 5ZI5-A nrPDB 317 6e-87 Sequences not found previously or not previously below threshold: 4FGM-A nrPDB 37 0.026 1BQB-A nrPDB 35 0.11 3CQB-A nrPDB 31 1.5 5TON-A nrPDB 31 2.3 1DY6-A nrPDB 30 2.6 4FS8-A nrPDB 30 3.0 5IV5-YD nrPDB 30 3.9 CONVERGED! >5FWQ-A nrPDB Length = 633 Score = 879 bits (2272), Expect = 0.0, Method: Composition-based stats. Identities = 611/611 (100%), Positives = 611/611 (100%) Query: 1 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL 60 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL Sbjct: 15 MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL 74 Query: 61 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT 120 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT Sbjct: 75 TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT 134 Query: 121 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP 180 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP Sbjct: 135 PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP 194 Query: 181 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES 240 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES Sbjct: 195 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES 254 Query: 241 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH 300 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH Sbjct: 255 MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH 314 Query: 301 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET 360 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET Sbjct: 315 SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET 374 Query: 361 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI 420 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI Sbjct: 375 HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI 434 Query: 421 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK 480 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK Sbjct: 435 TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK 494 Query: 481 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL 540 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL Sbjct: 495 EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL 554 Query: 541 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT 600 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT Sbjct: 555 RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT 614 Query: 601 AMLVGKDLKVD 611 AMLVGKDLKVD Sbjct: 615 AMLVGKDLKVD 625 >4GAA-A nrPDB Length = 609 Score = 814 bits (2103), Expect = 0.0, Method: Composition-based stats. Identities = 412/607 (67%), Positives = 505/607 (83%), Gaps = 1/607 (0%) Query: 4 IVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIE 63 + D S ASP KH+HL+ VDFT R + + +LTV+S +D+L SL+LDTKDLTI+ Sbjct: 1 MADPSSFASPEKF-NIKHMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIK 59 Query: 64 KVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQ 123 KV +NG++ +ALG S+KG+P+EI+LP +L++ QE+++EI TSPKSSALQWL EQ Sbjct: 60 KVAVNGKDATFALGTTHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLNKEQ 119 Query: 124 TSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPE 183 T+GK HPYLFSQCQA HCR+I+PCQDTPSVK TY ++VSVPKEL+ALMSA+RDGE + Sbjct: 120 TAGKIHPYLFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMALMSALRDGELSEQS 179 Query: 184 DPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLK 243 D +RKIY+F Q VPIP YLIALVVGALE R++GPRT +W+EKE +E S YEF+ETE MLK Sbjct: 180 DSNRKIYRFKQNVPIPSYLIALVVGALEGRKVGPRTTIWTEKELLEPSVYEFAETEKMLK 239 Query: 244 IAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWT 303 AEDL GPYVWGQYDLL+LPPSFPYGGMENPCLTFVTPT+LAGD+SL++VIAHEISHSWT Sbjct: 240 YAEDLAGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLASVIAHEISHSWT 299 Query: 304 GNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPF 363 GNLVTN+TW++FWLNEGHTVYLER I GRL+GE+FR F ALGGW ELQNSV TFG T+P Sbjct: 300 GNLVTNETWENFWLNEGHTVYLERRIDGRLYGEEFRQFKALGGWKELQNSVNTFGATNPL 359 Query: 364 TKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTD 423 T LV +L ++D D A+SSVPYEKGFALLFYLEQLLGGPEIFLGFLK+Y++ F++KS+TT+ Sbjct: 360 TNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAFKSVTTE 419 Query: 424 DWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDD 483 +WK FLYSYFKDKVD+L++VDW W+++PG+PP++P YDMTL NACI L Q+W+ A E D Sbjct: 420 EWKKFLYSYFKDKVDILDKVDWKGWMHTPGMPPVQPKYDMTLANACITLGQKWVKATESD 479 Query: 484 LNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLC 543 L SF+A D+KDLSSHQL E LA L PLP+ H+KRMQEVYN N + NSEIRFRWLRLC Sbjct: 480 LGSFSADDVKDLSSHQLIEVLAILLLEKPLPVSHVKRMQEVYNLNDVKNSEIRFRWLRLC 539 Query: 544 IQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAML 603 I++ WED IPLAL MATEQGRMKFTRPL++DL F+K+ +Q V T+ ++++ MHPVT ML Sbjct: 540 IRAGWEDVIPLALAMATEQGRMKFTRPLYRDLYNFEKAREQTVNTFLKNRSFMHPVTEML 599 Query: 604 VGKDLKV 610 V KDL + Sbjct: 600 VAKDLHI 606 >2XPY-A nrPDB Length = 632 Score = 634 bits (1634), Expect = 0.0, Method: Composition-based stats. Identities = 247/632 (39%), Positives = 365/632 (57%), Gaps = 41/632 (6%) Query: 2 PEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLR---SLVLDTK 58 PE D +L++ H L SV F + ++G+ ++ + L LDT Sbjct: 15 PEY-DQSTLSNYKDFAVL-HTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTS 72 Query: 59 DLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQW 118 L +++V I+G + + + +R+ GS + I+ S N + I F T+ K +ALQW Sbjct: 73 YLDVQEVHIDGSKADFQIEQRKEPLGSRLVIN---NASCNDNFTLNIQFRTTDKCTALQW 129 Query: 119 LTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGE 178 L +QT G PY+FSQ +AIH R++ PC DTPSVK T+TA + P L + S IR Sbjct: 130 LNSKQTKGG-KPYVFSQLEAIHARSLFPCFDTPSVKSTFTASIESP--LPVVFSGIR--- 183 Query: 179 TPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEF-SE 237 + IY+F QKVPIP YLI + G L S IGPR+ V++E +++ +EF ++ Sbjct: 184 -IEDTSKDTNIYRFEQKVPIPAYLIGIASGDLSSAPIGPRSTVYTEPFRLKDCQWEFEND 242 Query: 238 TESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHE 297 E ++ AE + Y WG YD+LV S+PYGGME+P +TF TPTL+A D+S +VIAHE Sbjct: 243 VEKFIQTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLIAHDRSNIDVIAHE 302 Query: 298 ISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTF 357 ++HSW+GNLVTN +W+HFWLNEG TVYLER I G + GE RHF+AL GW +LQNS+ + Sbjct: 303 LAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNSIDSM 362 Query: 358 GETHPFTKLVVDLTD-IDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFS 416 + F+ LV +L D DPD A+S+VPYEKGF LLF+LE +LGG F F++ Y +KF+ Sbjct: 363 KDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFA 422 Query: 417 YKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRW 476 KS+ T + D LY ++ +K ++L+ VDW WLY PG+PP +P++ L + L+ +W Sbjct: 423 KKSLDTFQFLDTLYEFYPEKKEILDSVDWETWLYKPGMPP-RPHFITALADNVYQLADKW 481 Query: 477 I------TAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQR------------APLPLGHI 518 + ED + FNA D+KD +S+QL FL Q A P+ Sbjct: 482 VEMAQHLKTTEDFRSEFNAIDIKDFNSNQLVLFLETLTQNGHSNKKPKDFDWAKFPVAS- 540 Query: 519 KRMQEVYNFNAI--NNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLA 576 + + ++Y N + N+E+ F+ + I +K ++ GRMKF RP ++ L Sbjct: 541 RALLDIYQDNIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGTVGRMKFVRPGYRLLN 600 Query: 577 AFDKSHDQAVRTYQEHKASMHPVTAMLVGKDL 608 + D+ A+ T+ + K + HP+ LV +DL Sbjct: 601 SVDRR--LALATFDKFKDTYHPICKALVKQDL 630 >3CIA-A nrPDB Length = 605 Score = 604 bits (1558), Expect = e-173, Method: Composition-based stats. Identities = 221/603 (36%), Positives = 344/603 (57%), Gaps = 33/603 (5%) Query: 17 CRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVI---NGQEVK 73 + H++L +VDF +++L+G A L++ DN L+LDT+DL I +V+ GQ VK Sbjct: 26 VKATHVYLDLNVDFDKKSLSGFAELSLDWFTDNKAPLILDTRDLVIHRVMAKNSQGQWVK 85 Query: 74 --YALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPY 131 Y L +R GS + I+ P+ K + + + ++ K++ LQWL+ EQT+GKE P+ Sbjct: 86 VNYDLAKRDDVLGSKLTINTPLNAKK-----VRVYYNSTEKATGLQWLSAEQTAGKEKPF 140 Query: 132 LFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYK 191 LFSQ QAIH R+ +P QDTPSV++TYTA ++ K+L+A+MSA + T D Y Sbjct: 141 LFSQNQAIHARSWIPIQDTPSVRVTYTARITTDKDLLAVMSANNEPGTERDGD-----YF 195 Query: 192 FIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGP 251 F IP YLIA+ VG LE + + +T +++E ++ + EF +T++M+ AE + G Sbjct: 196 FSMPQAIPPYLIAIGVGDLEFKAMSHQTGIYAESYILDAAVAEFDDTQAMIDKAEQMYGK 255 Query: 252 YVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKT 311 Y WG+YDLL+LPPSFP+GGMENP L+F+TPT++AGDKSL N+IAHE++HSW+GNLVTN++ Sbjct: 256 YRWGRYDLLMLPPSFPFGGMENPRLSFITPTVVAGDKSLVNLIAHELAHSWSGNLVTNES 315 Query: 312 WDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLT 371 W WLNEG T Y+E I +FG G +L + + T+L +DL Sbjct: 316 WRDLWLNEGFTSYVENRIMEAVFGTDRAVMEQALGAQDLNAEILELDASD--TQLYIDLK 373 Query: 372 DIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYS 431 DPD A+S VPY KG L YLE+ G E F F+ Y + +++S+ TD++ +L + Sbjct: 374 GRDPDDAFSGVPYVKGQLFLMYLEEKF-GRERFDAFVLEYFDSHAFQSLGTDNFVKYLKA 432 Query: 432 YFKDKV-DVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNAT 490 DK ++++ + N W++ GLP P +NA + ++ D+L Sbjct: 433 NLTDKYPNIVSDNEINEWIFKAGLPSYAPQ---PTSNAFKVIDKQINQLVTDELT----- 484 Query: 491 DLKDLSSHQ--LNEFLAQTLQRAPLPLGHIK--RMQEVYNFNAINNSEIRFRWLRLCIQS 546 L+ L + Q L+E+L + P+ L H + + + ++ +N+EI W L +++ Sbjct: 485 -LEQLPTAQWTLHEWL-HFINNLPVDLDHQRMVNLDKAFDLTNSSNAEIAHAWYLLSVRA 542 Query: 547 KWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGK 606 +++ P K GR K PL+K+LA +S AV Y++ + H + V Sbjct: 543 DYKEVYPAMAKYLKSIGRRKLIVPLYKELAKNAESKAWAVEVYKQARPGYHGLAQGTVDG 602 Query: 607 DLK 609 LK Sbjct: 603 VLK 605 >5C97-A nrPDB Length = 912 Score = 420 bits (1078), Expect = e-117, Method: Composition-based stats. Identities = 114/464 (24%), Positives = 199/464 (42%), Gaps = 32/464 (6%) Query: 13 PASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKV----VIN 68 P +V ++ L + T T G+ ++VQ+ + ++L + I +V ++ Sbjct: 46 PTAVVPLRY-ELSLHPNLTSMTFRGSVTISVQALQVTWN-IILHSTGHNISRVTFMSAVS 103 Query: 69 GQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQT--SG 126 QE + + E +Y G + I P AL ++I + + SS + T S Sbjct: 104 SQEKQAEILEY-AYHGQ-IAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESN 161 Query: 127 KEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPS 186 ++ + +Q + + R+ PC D P+ K T+ ++ ++ AL + + D Sbjct: 162 EKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVL--DDG 219 Query: 187 RKIYKFIQKVPIPCYLIALVVGA---LESRQIGPRTLVWSEKEQVEKSAYEFSETESMLK 243 +F + V + YL+A +VG L G +++ E++ + Y T +L+ Sbjct: 220 LVQDEFSESVKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLE 279 Query: 244 IAEDLGGP-YVWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLL--------AGDKSLSNV 293 ++ Y + DL+ +P F G MEN L TF TLL A K ++ + Sbjct: 280 FFQNYFEIQYPLKKLDLVAIP-DFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKI 338 Query: 294 IAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNS 353 IAHE++H W GNLVT K W+ WLNEG ++E ++F E + + L + Sbjct: 339 IAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKK 398 Query: 354 VKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVE 413 + +HP + V I+ + S+ Y KG +LL L+ L ++F + Y+ Sbjct: 399 -DSLNSSHPISSSVQSSEQIEE--MFDSLSYFKGSSLLLMLKTYL-SEDVFQHAVVLYLH 454 Query: 414 KFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPI 457 SY SI +DD D +DV W G P + Sbjct: 455 NHSYASIQSDDLWDSFNEVTNQTLDVKRM--MKTWTLQKGFPLV 496 >5DLL-A nrPDB Length = 867 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 106/474 (22%), Positives = 193/474 (40%), Gaps = 46/474 (9%) Query: 22 LHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQS 81 HL +D ++ +T + + +LVLD +L + + +N + + E Sbjct: 31 THLIFELDESKTRVTANLYIVANRENRENNTLVLDGVELKLLSIKLNNKHLS--PAEFAV 88 Query: 82 YKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHC 141 + + ++P + V++ E +P ++ L SG +QC+A Sbjct: 89 NENQLIINNVPE------KFVLQTVVEINPSAN--TSLEGLYKSGD---VFSTQCEATGF 137 Query: 142 RAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYK--FIQKVPIP 199 R I D P V +T ++ K+ ++ + +G+ D D S + + P Sbjct: 138 RKITYYLDRPDVMAAFTVKIIADKKKYPII--LSNGDKIDSGDISDNQHFAVWKDPFKKP 195 Query: 200 CYLIALVVGALES--------RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGP 251 CYL ALV G L S Q +++ K+ ++K Y + +K ED G Sbjct: 196 CYLFALVAGDLASIKDTYITKSQRKVSLEIYAFKQDIDKCHYAMQAVKDSMKWDEDRFGL 255 Query: 252 YVWGQYDLLVLPPSFPYGGMENPCLT-FVTPTLLAGDKSLSN--------VIAHEISHSW 302 ++V P F G MEN L F T ++A +K+ ++ V+ HE H+W Sbjct: 256 EYDLDTFMIVAVPDFNAGAMENKGLNIFNTKYIMASNKTATDKDFELVQSVVGHEYFHNW 315 Query: 303 TGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHP 362 TG+ VT + W L EG TV+ ++ L + + + + S + + P Sbjct: 316 TGDRVTCRDWFQLSLKEGLTVFRDQEFTSDLNSRDVKRIDDVR----IIRSAQFAEDASP 371 Query: 363 FTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITT 422 + + + I+ + Y+ Y KG ++ + LL G E F +K Y E+ +++T Sbjct: 372 MSHPIRPESYIEMNNFYTVTVYNKGAEIIRMIHTLL-GEEGFQKGMKLYFERHDGQAVTC 430 Query: 423 DDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIK--PNYDMTLTNACIALSQ 474 DD+ + + + + + W G P IK NYD + + L Q Sbjct: 431 DDFVNAMADA-----NNRDFSLFKRWYAQSGTPNIKVSENYDASSQTYSLTLEQ 479 >1Z1W-A nrPDB Length = 780 Score = 396 bits (1017), Expect = e-110, Method: Composition-based stats. Identities = 108/448 (24%), Positives = 181/448 (40%), Gaps = 46/448 (10%) Query: 23 HLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSY 82 L D +RT GT +T + + +VLD L I + +NG++ + +Y Sbjct: 7 DLTLDFDIQKRTFNGTETITADAGD-----IVLDAVGLQINWMKVNGRDTAF------TY 55 Query: 83 KGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCR 142 G + A +Q IEISF S L+ +G+E+ + + +A R Sbjct: 56 DGQTVR-----APGDSQPQKIEISFAGKVSDS----LSGIYYAGRENGMITTHFEATDAR 106 Query: 143 AILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYL 202 + PC D P+ K + V + K+ A+ + E RK+ +F + YL Sbjct: 107 RMFPCVDHPAYKAVFAITVVIDKDYDAISNMPPK----RIEVSERKVVEFQDTPRMSTYL 162 Query: 203 IALVVGAL--ESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGG-PYVWGQYDL 259 + + +G E + L+ + + + +S Y ++ E+ G PY + L Sbjct: 163 LYVGIGKFRYEYEKYRDIDLILASLKDI-RSKYPLDMARKSVEFYENYFGIPYALPKMHL 221 Query: 260 LVLPPSFPYGGMENPC-LTFVT-------PTLLAGDKSLSNVIAHEISHSWTGNLVTNKT 311 + P F G MEN +TF + + ++ +NVIAHEI+H W G+LVT K Sbjct: 222 IS-VPEFGAGAMENWGAITFREIYMDIAENSAVTVKRNSANVIAHEIAHQWFGDLVTMKW 280 Query: 312 WDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLT 371 W+ WLNE ++ LF E + + THP VD+ Sbjct: 281 WNDLWLNESFATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPI---EVDVR 337 Query: 372 DIDP-DVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLY 430 D D + + Y KG ++L +E G E F + Y+ + + D L+ Sbjct: 338 DPDEISQIFDEISYGKGASILRMIEDYAGYEE-FRKGISKYLNDHKFGNAEGSD----LW 392 Query: 431 SYFKDKVDVLNQVDWNAWLYSPGLPPIK 458 + +D + W+ +PG P IK Sbjct: 393 TAIEDVSGKPVKRVMEYWIKNPGYPVIK 420 >4Q4I-A nrPDB Length = 891 Score = 383 bits (983), Expect = e-106, Method: Composition-based stats. Identities = 109/481 (22%), Positives = 189/481 (39%), Gaps = 54/481 (11%) Query: 18 RTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALG 77 + + L +D + +T + + L L+ +DL + V IN + Sbjct: 40 QITDIDLTFDLDAQKTVVTAVS--QAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKE 97 Query: 78 ERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQ 137 E G+ + +LP ++I E SP ++ L SG L +QC+ Sbjct: 98 EE----GALVISNLPE------RFTLKIINEISPAAN--TALEGLYQSGDA---LCTQCE 142 Query: 138 AIHCRAILPCQDTPSVKLTYTAEVSVPKE----LVALMSAIRDGETPDPEDPSRKIYKFI 193 A R I D P V +T ++ K L++ + + GE + R ++ Sbjct: 143 AEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQGELEN----GRHWVQWQ 198 Query: 194 QKVPIPCYLIALVVGALE------SRQIGPRT--LVWSEKEQVEKSAYEFSETESMLKIA 245 P PCYL ALV G + + + G ++ ++ ++++ + + ++ +K Sbjct: 199 DPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWD 258 Query: 246 EDLGGPYVWGQYDLLVLPPSFPYGGMENPCLT-FVTPTLLA-----GDKS---LSNVIAH 296 E+ G ++V F G MEN L F + +LA DK + VI H Sbjct: 259 EERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGH 318 Query: 297 EISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKT 356 E H+WTGN VT + W L EG TV+ ++ L N + LQ + Sbjct: 319 EYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDA 378 Query: 357 FGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFS 416 HP +V I+ + Y+ YEKG ++ + LL G E F ++ Y E+ Sbjct: 379 SPMAHPIRPDMV----IEMNNFYTLTVYEKGAEVIRMIHTLL-GEENFQKGMQLYFERHD 433 Query: 417 YKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLP--PIKPNYDMTLTNACIALSQ 474 + T DD+ + ++ + W G P +K +Y+ + +SQ Sbjct: 434 GSAATCDDFVQAMEDA-----SNVDLSHFRRWYSQSGTPIVTVKDDYNPETEQYTLTISQ 488 Query: 475 R 475 R Sbjct: 489 R 489 >4QHP-A nrPDB Length = 870 Score = 376 bits (965), Expect = e-104, Method: Composition-based stats. Identities = 108/472 (22%), Positives = 172/472 (36%), Gaps = 54/472 (11%) Query: 25 RCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYAL-GERQSYK 83 D + LTV+ Q LVLD + V ING Y L GE + Sbjct: 25 DLHFDINEPQTVVKSRLTVEPQRVG-EPLVLDGS-AKLLSVKINGAAADYVLEGETLTIA 82 Query: 84 GSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRA 143 G P E +E+ E P + + L SG LF+QC+ R Sbjct: 83 GVPSE-----------RFTVEVETEILPAEN--KSLMGLYASGGN---LFTQCEPEGFRK 126 Query: 144 ILPCQDTPSVKLTYTAEVSVPKE----LVALMSAIRDGETPDPEDPSRKIYKFIQKVPIP 199 I D P V +T + K+ L++ + I GE D R K+ P Sbjct: 127 ITFYIDRPDVMSKFTTTIVADKKRYPVLLSNGNKIDGGEFSD----GRHWVKWEDPFSKP 182 Query: 200 CYLIALVVGALESRQ--------IGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGP 251 YL ALV G L + + ++ + K + ++ +K E G Sbjct: 183 SYLFALVAGDLAVTEDYFTTMSGRNVKIEFYTTEADKPKVGFAVESLKNAMKWDETRFGL 242 Query: 252 YVWGQYDLLVLPPSFPYGGMENPCLT-FVTPTLLAGDKSLSN--------VIAHEISHSW 302 ++V F G MEN L F T +LA ++ ++ V+ HE H+W Sbjct: 243 EYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADSRTATDTDFEGIESVVGHEYFHNW 302 Query: 303 TGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHP 362 TGN VT + W L EG TV+ ++ G R + + Q HP Sbjct: 303 TGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRAVRRIENIRLLRQHQFPEDAGPTAHP 362 Query: 363 FTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITT 422 + + + Y+ YEKG ++ LL G E F +K Y ++ +++T Sbjct: 363 VRPASYE----EMNNFYTMTVYEKGAEVVRMYHTLL-GEEGFQKGMKLYFQRHDGQAVTC 417 Query: 423 DDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQ 474 DD++ + + +N + W G P ++ + + + Q Sbjct: 418 DDFRAAMADA-----NGINLDQFALWYSQAGTPVLEAEGRLKNNIFELTVKQ 464 >5LG6-A nrPDB Length = 968 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 112/513 (21%), Positives = 193/513 (37%), Gaps = 53/513 (10%) Query: 49 NLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFE 108 + + L T+ + + +V + + L +L +E F+ Sbjct: 101 HSKKLNYTTQGHMVVLRGVGDSQVPEIDRTELVELTEYLVVHLKGSLQPGHMYEMESEFQ 160 Query: 109 TSPKSSALQWLTPEQTSGKEHPYLFS-QCQAIHCRAILPCQDTPSVKLTYTAEVSVPKEL 167 + E G L + Q Q+ R PC D P++K T+ + P L Sbjct: 161 GELADDLAGFYRSEYMEGNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNL 220 Query: 168 VALMSAIRDGE-TPDPEDPSRKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTLVW 222 AL + G TP EDP+ + +F + YL+A +V +S Q G +W Sbjct: 221 TALSNMPPKGSSTPLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIW 280 Query: 223 SEKEQVEKSA--YEFSETESMLKI-AEDLGGPYVWGQYDLLVLPPSFPYGGMENPCL-TF 278 + + + Y + T +L A Y + D + LP F G MEN L T+ Sbjct: 281 ARPNAIAEGHGMYALNVTGPILNFFANHYNTSYPLPKSDQIALP-DFNAGAMENWGLVTY 339 Query: 279 VTPTLL--------AGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHIC 330 LL + + + VIAHE++H W GNLVT W+ WLNEG Y+E Sbjct: 340 RENALLFDPQSSSISNKERVVTVIAHELAHQWFGNLVTLAWWNDLWLNEGFASYVE--YL 397 Query: 331 GRLFGEKFRHFNALGGWGELQN--SVKTFGETHPFTKLVVDLTDI-DPDVAYSSVPYEKG 387 G E + L G++ +V +HP T ++ + S+ Y KG Sbjct: 398 GADHAEPTWNLKDLIVPGDVYRVMAVDALASSHPLTTPAEEVNTPAQISEMFDSISYSKG 457 Query: 388 FALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDV----LNQV 443 +++ L L ++F L +Y+ F+Y++ T D + L + + + Sbjct: 458 ASVIRMLSNFL-TEDLFKEGLASYLHAFAYQNTTYLDLWEHLQKAVDAQTSIRLPDTVRA 516 Query: 444 DWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEF 503 + W G P I D N + ++ E ++ +A D + Sbjct: 517 IMDRWTLQMGFPVI--TVDTKTGNIS---QKHFLLDSESNVTRSSAFD---------YLW 562 Query: 504 LAQTLQRAPLPLGHIKR--MQEVYNFNAINNSE 534 + +P+ IK MQ+ Y ++ ++ Sbjct: 563 I--------VPISSIKNGVMQDHYWLRDVSQAQ 587 >5Y1X-A nrPDB Length = 914 Score = 359 bits (921), Expect = 2e-99, Method: Composition-based stats. Identities = 112/492 (22%), Positives = 184/492 (37%), Gaps = 54/492 (10%) Query: 13 PASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEV 72 P+ ++ L ++ + + + LV D L I ++ IN + Sbjct: 35 PSGFI-INNVTLNINIHDNETIVRSVLDMDISKHNVG-EDLVFDGVGLKINEISINNK-- 90 Query: 73 KYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYL 132 K GE +Y + I E+ P+++ LT K + Sbjct: 91 KLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEV--IIHPETNYA--LTGLY---KSKNII 143 Query: 133 FSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKE----LVALMSAIRDGETPDPEDPSRK 188 SQC+A R I D P + Y V+ KE L++ + + E P +R Sbjct: 144 VSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEFEIPGGRHGAR- 202 Query: 189 IYKFIQKVPIPCYLIALVVGALE---------SRQIGPRTLVWSEKEQVEKSAYEFSETE 239 F PCYL A+V G L+ + V+SE++ V K + + Sbjct: 203 ---FNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSKLQWALECLK 259 Query: 240 SMLKIAEDLGGPYVWGQYDL----LVLPPSFPYGGMENPCLT-FVTPTLLAGDKS----- 289 + ED G +YDL LV F G MEN L F +LLA K+ Sbjct: 260 KSMAFDEDYFGL----EYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFS 315 Query: 290 ---LSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGG 346 + V+ HE H++TGN VT + W L EG TV+ E E + Sbjct: 316 YARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSE----EMTKTVTTRLS 371 Query: 347 WGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLG 406 +L SV+ ++ P + + + + + Y++ Y+KG ++ +L G E + Sbjct: 372 HVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTIL-GEEYYKK 430 Query: 407 FLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDV--LNQVDWNAWLYSPGLPPI--KPNYD 462 Y++K + T +D+ + +K K N + W G P + K NYD Sbjct: 431 GFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSGTPHVSFKYNYD 490 Query: 463 MTLTNACIALSQ 474 I ++Q Sbjct: 491 AEKKQYSIHVNQ 502 >3QNF-A nrPDB Length = 954 Score = 359 bits (920), Expect = 3e-99, Method: Composition-based stats. Identities = 99/488 (20%), Positives = 175/488 (35%), Gaps = 52/488 (10%) Query: 13 PASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKV----VIN 68 P V H L + T T GT + + + + +++L + L I + Sbjct: 61 PEYVIPV-HYDLLIHANLTTLTFWGTTKVEITASQPTS-TIILHSHHLQISRATLRKGAG 118 Query: 69 GQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQ--TSG 126 + + L + + + + P L + I + + + + G Sbjct: 119 ERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEG 178 Query: 127 KEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPS 186 + +Q + R PC D P+ K +++ ++ +A+ + E Sbjct: 179 ELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLI 238 Query: 187 RKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESML 242 F V + YL+A ++ ES + G + V++ +++ ++ Y ++L Sbjct: 239 ED--HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLL 296 Query: 243 KIAEDLG-GPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSN--------- 292 + ED PY + DL +P F G MEN LT + L D S+ Sbjct: 297 EFYEDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITM 355 Query: 293 VIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQN 352 +AHE++H W GNLVT + W+ WLNEG ++E E G + Sbjct: 356 TVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAM- 414 Query: 353 SVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYV 412 V +HP + V + I + V Y+KG +L L + L F + Y+ Sbjct: 415 EVDALNSSHPVSTPVENPAQIRE--MFDDVSYDKGACILNMLREYLSADA-FKSGIVQYL 471 Query: 413 EKFSYKSITTDDWKDFLYSYFK-----------------------DKVDVLNQVDWNAWL 449 +K SYK+ +D D + S + V + N W Sbjct: 472 QKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWT 531 Query: 450 YSPGLPPI 457 G P I Sbjct: 532 LQKGFPLI 539 >5LHD-A nrPDB Length = 950 Score = 357 bits (916), Expect = 7e-99, Method: Composition-based stats. Identities = 108/455 (23%), Positives = 182/455 (40%), Gaps = 41/455 (9%) Query: 36 TGTAALTVQSQEDNLRSLVLDTKDLTI-----EKVVING----QEVKYALGERQSYKGSP 86 + T T + D +++ +K L +VV+ G Q E Sbjct: 89 SSTVRFTCKEATD---VIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPT-EY 144 Query: 87 MEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFS-QCQAIHCRAIL 145 + + L +L K+ + ++ FE + E G + + Q QA R Sbjct: 145 LVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSF 204 Query: 146 PCQDTPSVKLTYTAEVSVPKELVALMSAIRDGE-TPDPEDPSRKIYKFIQKVPIPCYLIA 204 PC D P++K + + PK+L AL + + G TP PEDP+ + +F + YL+A Sbjct: 205 PCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLA 264 Query: 205 LVVGALES----RQIGPRTLVWSEKEQVEKSA--YEFSETESMLKI-AEDLGGPYVWGQY 257 +V + G +W+ + Y + T +L A PY + Sbjct: 265 FIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKS 324 Query: 258 DLLVLPPSFPYGGMENPCL-TFVTPTLL--------AGDKSLSNVIAHEISHSWTGNLVT 308 D + LP F G MEN L T+ +LL + + + VIAHE++H W GNLVT Sbjct: 325 DQIGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVT 383 Query: 309 NKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQN--SVKTFGETHPFTKL 366 + W+ WLNEG Y+E G + E + L ++ +V +HP + Sbjct: 384 IEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTP 441 Query: 367 VVDLTDI-DPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDW 425 ++ + ++ Y KG ++L L L ++F L +Y+ F+Y++ + Sbjct: 442 ASEINTPAQISELFDAISYSKGASVLRMLSSFL-SEDVFKQGLASYLHTFAYQNTIYLNL 500 Query: 426 KDFLYSYFKDKVDVL---NQVDWNAWLYSPGLPPI 457 D L ++ L + N W G P I Sbjct: 501 WDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVI 535 >3SE6-A nrPDB Length = 967 Score = 352 bits (904), Expect = 2e-97, Method: Composition-based stats. Identities = 103/492 (20%), Positives = 186/492 (37%), Gaps = 58/492 (11%) Query: 13 PASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEV 72 P+ V H L + T + + V + + ++L +KDL I + +E Sbjct: 70 PSVVIPL-HYDLFVHPNLTSLDFVASEKIEVL-VSNATQFIILHSKDLEITNATLQSEED 127 Query: 73 K------YALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWL-TPEQTS 125 L + + +P L+ + + + + F+ + + +T Sbjct: 128 SRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTL 187 Query: 126 GKEHPYLF-SQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPED 184 G E L + + R PC D P K ++ ++ +AL + + +T + E Sbjct: 188 GGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSN-MPKVKTIELEG 246 Query: 185 PSRKIYKFIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETES 240 + + F V + YL+A +V S G + +++ ++ ++ Y + Sbjct: 247 GLLEDH-FETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLK 305 Query: 241 MLKIAEDLGGPY-VWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLLAGDKS--------L 290 +L E Y + DL+ +P F G MEN L T+ +LL K+ + Sbjct: 306 LLDFYEKYFDIYYPLSKLDLIAIP-DFAPGAMENWGLITYRETSLLFDPKTSSASDKLWV 364 Query: 291 SNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGEL 350 + VIAHE++H W GNLVT + W+ WLNEG Y+E + E L E+ Sbjct: 365 TRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEV 424 Query: 351 QNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKA 410 + + P +K T I + V Y KG +L L+ L G E F + Sbjct: 425 ITK-DSLNSSRPISKPAETPTQIQE--MFDEVSYNKGACILNMLKDFL-GEEKFQKGIIQ 480 Query: 411 YVEKFSYKSITTDDWKDF-------------------------LYSYFKDKVDVLNQVDW 445 Y++KFSY++ DD + ++ + +V + Sbjct: 481 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMT- 539 Query: 446 NAWLYSPGLPPI 457 W G+P + Sbjct: 540 -TWTLQKGIPLL 550 >4KXA-A nrPDB Length = 888 Score = 341 bits (873), Expect = 7e-94, Method: Composition-based stats. Identities = 104/486 (21%), Positives = 184/486 (37%), Gaps = 38/486 (7%) Query: 16 VCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYA 75 H L T TGT ++++ R L L ++ I ++ + Sbjct: 21 FVNPVHYDLHVKPLLEEDTYTGTVSISIN-LSAPTRYLWLHLRETRITRLPELKRPSGDQ 79 Query: 76 LG-----ERQSYKGSPMEISLPIALSKNQ-EIVIEISFETSPKSSALQWLTPEQTSGKE- 128 + E + + +E + S ++ + F S + + T Sbjct: 80 VQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGRV 139 Query: 129 HPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRK 188 + + R PC D P+ K TYT ++ PKE AL + E + +R Sbjct: 140 KSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRT 199 Query: 189 IYKFIQKVPIPCYLIALVVGALESRQ----IGPRTLVWSEKEQVEKSAYEFSETESMLKI 244 F + VP+ YL+ V +S + G ++ + EQ + Y + T+S+ Sbjct: 200 T--FEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDY 257 Query: 245 AEDLG-GPYVWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLL--------AGDKSLSNVI 294 E+ Y + D + +P F G MEN L T+ LL + + ++ V+ Sbjct: 258 FEEYFAMNYSLPKLDKIAIP-DFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVV 316 Query: 295 AHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQ--N 352 AHE+ H W GN+VT W+ WLNEG + E G E ++ Sbjct: 317 AHELVHQWFGNIVTMDWWEDLWLNEGFASFFE--FLGVNHAETDWQMRDQMLLEDVLPVQ 374 Query: 353 SVKTFGETHPFTKLVVDLTDIDPDVA-YSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAY 411 + +HP +V +T D + + + Y KG ++L LE + PE F + Y Sbjct: 375 EDDSLMSSHPI---IVTVTTPDEITSVFDGISYSKGSSILRMLEDWI-KPENFQKGCQMY 430 Query: 412 VEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIA 471 +EK+ +K+ T D+ ++ ++ + + + W G P + N +T Sbjct: 431 LEKYQFKNAKTSDF----WAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFL 486 Query: 472 LSQRWI 477 L R Sbjct: 487 LDPRAN 492 >4WZ9-A nrPDB Length = 957 Score = 339 bits (870), Expect = 2e-93, Method: Composition-based stats. Identities = 106/481 (22%), Positives = 187/481 (38%), Gaps = 40/481 (8%) Query: 13 PASVCRTKH-LHLRCSVDFTRRTLTGTAALTVQSQED------NLRSLVLDTKDLTIEKV 65 P + + LHLR + RT TGT + +Q + + R LV+ + ++ Sbjct: 49 PTTSIPIHYDLHLRTEIHRNERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKVSSLPN 108 Query: 66 VINGQEVKYALGERQSYKGSPME---ISLPIALSKNQEIVIEISFETSPKSSALQWL-TP 121 + G +G+ Q + E + P L ++E++F+ ++ + + Sbjct: 109 GVTGAPT--LIGDVQYSTDTTFEHITFTSPTILQPGT-YLLEVAFQGRLATNDDGFYVSS 165 Query: 122 EQTSGKEHPYLFS-QCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP 180 E YL + Q ++ R PC D P +K T+T ++ A+ + + T Sbjct: 166 YVADNGERRYLATTQFESTSARMAFPCYDEPGLKATFTVSITHSLSYKAISN-MPQKTTT 224 Query: 181 DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES 240 D E R F + + YL+A VV + R G + V+ ++ + Sbjct: 225 DIETDMRT-TFFEKTPAMSTYLLAFVVSDFQLRLSGAQR-VYVRPNAFNEATFALEAGVK 282 Query: 241 MLKI-AEDLGGPY--VWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLL--------AGDK 288 +LK+ + LG PY + D + +P F G MEN L T+ LL G Sbjct: 283 ILKVLDDHLGIPYDTYMPKLDQIAIP-DFAAGAMENWGLVTYREQALLFNPAVSTYRGKT 341 Query: 289 SLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWG 348 +++ IAHE +H W GNLV+ + W++ WLNEG E + + + Sbjct: 342 NVATTIAHEYAHQWFGNLVSPEWWEYIWLNEGFATLYEFYALDMAYPGQEYWELFNQQVI 401 Query: 349 ELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFL 408 + T P T + + V Y+K ++L + +L G + + L Sbjct: 402 QYAMGQDGQASTRPMN--WNAATPGEISALFDRVAYDKSGSVLNMMRHVL-GDDNWKAGL 458 Query: 409 KAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVD----WNAWLYSPGLP--PIKPNYD 462 KAY+ + + + L S + K + N V W G P ++ +YD Sbjct: 459 KAYLTDRALQGAVDEQLYAGLQSAIEGKGVLPNGVTVAQIMRTWTNEAGYPVLNVRRSYD 518 Query: 463 M 463 Sbjct: 519 T 519 >5ZI5-A nrPDB Length = 921 Score = 317 bits (813), Expect = 6e-87, Method: Composition-based stats. Identities = 102/531 (19%), Positives = 194/531 (36%), Gaps = 80/531 (15%) Query: 22 LHLRCSVDFTRRTLTGTAALTVQS---QEDNLRSLVLDTKDLTIEKVVINGQEVKYALGE 78 +H+ +D +++ + A LTV + + LVLD +++T+ + +N +K E Sbjct: 50 IHVDLQIDLSKKPVESKARLTVVPNLNVDSHSNDLVLDGENMTLVSLQMNDNLLKE--NE 107 Query: 79 RQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQA 138 + K S + ++P +N IE+ TS +T G + ++ Sbjct: 108 YELTKDSLIIKNIP----QNTPFTIEM---TSLLGENTDLFGLYETEG----VALVKAES 156 Query: 139 IHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYK--FIQKV 196 R + D P TY + +E ++ + +G + ++ ++ ++ V Sbjct: 157 EGLRRVFYLPDRPDNLATYKTTIIANQEDYPVL--LSNGVLIEKKELPLGLHSVTWLDDV 214 Query: 197 PIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEF----SETESMLKIAEDLGGPY 252 P P YL ALV G L+ R++ + + + + EF S T E L Sbjct: 215 PKPSYLFALVAGNLQ------RSVTYYQTKSGRELPIEFYVPPSATSKCDFAKEVLKEAM 268 Query: 253 VWGQY----------DLLVLPPSFPYGGMENPCLT-FVTPTLLAGDKSLSN--------V 293 W + ++ + G E L F T L A ++ ++ V Sbjct: 269 AWDERTFNLECALRQHMVAGVDKYASGASEPTGLNLFNTENLFASPETKTDLGILRVLEV 328 Query: 294 IAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNS 353 +AHE H W+G+ VT + W + L EG T + LFG L G Sbjct: 329 VAHEFFHYWSGDRVTIRDWFNLPLKEGLTTFRAAMFREELFGTDL--IRLLDG------- 379 Query: 354 VKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVE 413 K E P + + Y++ YEK + + L G E F+ + + + Sbjct: 380 -KNLDERAPRQSAYTAVRSL-----YTAAAYEKSADIFRMM-MLFIGKEPFIEAVAKFFK 432 Query: 414 KFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLP--PIKPNYDMTLTNACIA 471 ++T +D+ + + + + +W G+P + + + Sbjct: 433 DNDGGAVTLEDFIESI-----SNSSGKDLRSFLSWFTESGIPELIVTDELNPDTKQYFLK 487 Query: 472 LS-----QRWITAKEDDLNSFNATDLKD---LSSHQLNEFLAQTLQRAPLP 514 + R I L+S A + D + + EF + +Q P+P Sbjct: 488 IKTVNGRNRPIPILMGLLDSSGAEIVADKLLIVDQEEIEFQFENIQTRPIP 538 >4FGM-A nrPDB Length = 597 Score = 36.7 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 42/229 (18%), Positives = 69/229 (30%), Gaps = 51/229 (22%) Query: 237 ETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSN---- 292 + + + L + Y L + +GG+E+ + LL K L + Sbjct: 203 DLAKICETQISLFEEAPFQSYTFLTMVVGNGFGGLEHR----NSTALLCSRKDLISAHQY 258 Query: 293 -----------VIAHEISHSWTGNLVTNK-------------TWDHFWLNEGHTVYLERH 328 + HE HSW N+ T K + W EG T Y + + Sbjct: 259 EMNDNYQTFLSLCCHEYFHSW--NIKTLKPKAFLPYQLEKESYTEQLWFYEGMTSYFDDY 316 Query: 329 ICGRLFGEKFRHFNAL---------GGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAY 379 + + + L G G+ Q SV + + V+Y Sbjct: 317 LLHTSGIIDEKRYLKLLGDTLSRVERGAGQYQQSVTESSFLAWTKFYQQNENAPNSIVSY 376 Query: 380 SSVPYEKGFALLFYLEQLLGGPEIFL----GFLKAYVEKFSYKSITTDD 424 Y KG + L+ +L +K +F SI T D Sbjct: 377 ----YAKGALIALSLDLMLRLQSDHKLTLARVMKELWHEFGKTSIGTAD 421 >1BQB-A nrPDB Length = 301 Score = 34.8 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 56/161 (34%), Gaps = 9/161 (5%) Query: 292 NVIAHEISHSWTGNLVTNKTWDHF-WLNEGHTVYLERHICGRLF--GEKFRHFNALGGWG 348 +V+AHEI+H T + D LNE + + F GE G Sbjct: 140 DVVAHEITHGVTQQTANLEYKDQSGALNESFSDVFGYFVDDEDFLMGEDVYTPGKEGDAL 199 Query: 349 ELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFL 408 ++ + FG+ V D S +P + + ++ + +I+ L Sbjct: 200 RSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAI-GKSKSEQIYYRAL 258 Query: 409 KAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLN-QVDWNAW 448 Y+ S D KD LY KD + + + AW Sbjct: 259 TEYLTSNS----NFKDLKDALYQAAKDLYEQQTAEQVYEAW 295 >3CQB-A nrPDB Length = 107 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 266 FPYGGMENPCLTFVTPTLLAG--DKSLSNVIAHEISHSWTGNLVTN 309 F G + L V+ LL V+AHE+SH G++VT Sbjct: 57 FATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTM 102 >5TON-A nrPDB Length = 414 Score = 30.6 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 7/15 (46%), Positives = 9/15 (60%) Query: 297 EISHSWTGNLVTNKT 311 E+ H WTGN+ T Sbjct: 316 ELFHEWTGNVKTMAD 330 >1DY6-A nrPDB Length = 267 Score = 30.2 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 40/108 (37%), Gaps = 6/108 (5%) Query: 303 TGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHP 362 +GN ++ + F L +L + R+ L +++ + P Sbjct: 30 SGNTFGYRSDERFPLCSSFKGFLAAAVLERV------QQKKLDINQKVKYESRDLEYHSP 83 Query: 363 FTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKA 410 T D+A +++ Y A +E+ LGGPE F+++ Sbjct: 84 ITTKYKGSGMTLGDMASAALQYSDNGATNIIMERFLGGPEGMTKFMRS 131 >4FS8-A nrPDB Length = 383 Score = 30.2 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 12/27 (44%) Query: 277 TFVTPTLLAGDKSLSNVIAHEISHSWT 303 TF + D++ + +I H H W Sbjct: 311 TFPREKPVRVDRNTAEIIRHSRLHQWF 337 >5IV5-YD nrPDB Length = 391 Score = 29.8 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 18/134 (13%) Query: 449 LYSPGLPPIK----PNYDMTLTNACIALSQRWITAK-EDDLNSFNATDLKDLSSHQLNEF 503 L PG P + +YD N + L+ T D L N L+ S ++ Sbjct: 4 LQRPGYPNLSVKLFDSYDAWSNNRFVELAATITTLTMRDSLYGRNEGMLQFYDSKNIHTK 63 Query: 504 LAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRF---RWLRLCIQSKWEDAIPLALKMAT 560 + G+ V N N INN + R + + + SK ++ I + L Sbjct: 64 MD----------GNEIIQISVANANDINNVKTRIYGCKHFSVSVDSKGDNIIAIELGTIH 113 Query: 561 EQGRMKFTRPLFKD 574 +KF RP F D Sbjct: 114 SIENLKFGRPFFPD 127 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.121 0.304 Lambda K H 0.267 0.0371 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,419,219 Number of Sequences: 36641 Number of extensions: 755469 Number of successful extensions: 2179 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 1989 Number of HSP's gapped (non-prelim): 56 length of query: 611 length of database: 10,336,785 effective HSP length: 103 effective length of query: 508 effective length of database: 6,562,762 effective search space: 3333883096 effective search space used: 3333883096 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)