BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09938 (399 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1SMQ-A nrPDB 820 0.0 1H0O-A nrPDB 474 e-134 2UW2-A nrPDB 469 e-133 3HF1-A nrPDB 463 e-131 4DJN-A nrPDB 435 e-122 3OLJ-A nrPDB 422 e-118 1SMS-A nrPDB 399 e-111 2P1I-A nrPDB 386 e-107 2O1Z-A nrPDB 337 5e-93 4M1I-A nrPDB 139 2e-33 2RCC-A nrPDB 67 2e-11 1PIY-A nrPDB 62 4e-10 4DR0-A nrPDB 52 4e-07 4N83-A nrPDB 52 5e-07 4BMQ-A nrPDB 51 1e-06 3MJO-A nrPDB 50 2e-06 3DHZ-A nrPDB 49 4e-06 1UZR-A nrPDB 45 7e-05 6GP2-A nrPDB 44 9e-05 2BQ1-I nrPDB 44 1e-04 6EBP-A nrPDB 42 3e-04 6QRZ-A nrPDB 42 5e-04 3N37-A nrPDB 39 0.004 4AC8-A nrPDB 34 0.10 6CWO-A nrPDB 32 0.45 6CWP-A nrPDB 32 0.49 4WSS-A nrPDB 30 1.3 6B1L-A nrPDB 30 1.8 >1SMQ-A nrPDB Length = 399 Score = 820 bits (2118), Expect = 0.0, Method: Compositional matrix adjust. Identities = 399/399 (100%), Positives = 399/399 (100%) Query: 1 MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLK 60 MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLK Sbjct: 1 MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLK 60 Query: 61 SHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIH 120 SHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIH Sbjct: 61 SHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIH 120 Query: 121 DWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHS 180 DWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHS Sbjct: 121 DWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHS 180 Query: 181 ETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEG 240 ETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEG Sbjct: 181 ETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEG 240 Query: 241 VFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIV 300 VFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIV Sbjct: 241 VFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIV 300 Query: 301 TEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENI 360 TEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENI Sbjct: 301 TEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENI 360 Query: 361 SLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 SLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF Sbjct: 361 SLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 >1H0O-A nrPDB Length = 390 Score = 474 bits (1221), Expect = e-134, Method: Compositional matrix adjust. Identities = 237/392 (60%), Positives = 289/392 (73%), Gaps = 21/392 (5%) Query: 25 NLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLK--------EME--- 73 ++ L T+ ++ +++ LK D EN L S +V K E+E Sbjct: 3 SVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELESKA 62 Query: 74 ------KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMN 127 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + Sbjct: 63 PTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LK 121 Query: 128 ENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLI 187 +ER FIS VLAFFAASDGIVNENLVE FS EVQ+ EA+ FYGFQI +ENIHSE YSLLI Sbjct: 122 PDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLI 181 Query: 188 DTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSF 247 DTYIKDPKE E+LFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSF Sbjct: 182 DTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF 241 Query: 248 ASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIE 307 ASIFWLKKRG+MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+T AV IE Sbjct: 242 ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIE 301 Query: 308 QRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTN 367 Q + +ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFMENISL GKTN Sbjct: 302 QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTN 361 Query: 368 FFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 FFEKRV +YQ+ GVMS ST+ +FT + DF Sbjct: 362 FFEKRVGEYQRMGVMSNSTE---NSFTLDADF 390 >2UW2-A nrPDB Length = 332 Score = 469 bits (1207), Expect = e-133, Method: Compositional matrix adjust. Identities = 224/326 (68%), Positives = 264/326 (80%), Gaps = 4/326 (1%) Query: 74 KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFF 133 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + + ER+F Sbjct: 11 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWES-LKPEERYF 69 Query: 134 ISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKD 193 IS VLAFFAASDGIVNENLVE FS EVQI EA+ FYGFQI +ENIHSE YSLLIDTYIKD Sbjct: 70 ISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKD 129 Query: 194 PKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWL 253 PKE EFLFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSFASIFWL Sbjct: 130 PKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWL 189 Query: 254 KKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLD 313 KKRG MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+ AV IEQ + + Sbjct: 190 KKRGPMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTE 249 Query: 314 ALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRV 373 ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFMENISL GKTNFFEKRV Sbjct: 250 ALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRV 309 Query: 374 SDYQKAGVMSKSTKQEAGAFTFNEDF 399 +YQ+ GVMS T+ +FT + DF Sbjct: 310 GEYQRMGVMSSPTEN---SFTLDADF 332 >3HF1-A nrPDB Length = 351 Score = 463 bits (1192), Expect = e-131, Method: Compositional matrix adjust. Identities = 217/325 (66%), Positives = 266/325 (81%), Gaps = 4/325 (1%) Query: 75 EEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFI 134 EEPLL + R V+FPI+Y +IW+ YK+A+ASFWTAEE+DLSKD+ WN ++ +E++FI Sbjct: 31 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWN-KLKADEKYFI 89 Query: 135 SRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDP 194 S +LAFFAASDGIVNENLVE FS EVQ+PEA+ FYGFQI+IEN+HSE YSLLIDTYI+DP Sbjct: 90 SHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDP 149 Query: 195 KESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLK 254 K+ EFLFNAI T+P + +KA+WALRWI D + FGER+VAFA++EGVFFSGSFA+IFWLK Sbjct: 150 KKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLK 209 Query: 255 KRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDA 314 KRG+MPGLTFSNELI RDEGLH DFACL+F +L NKP V +I+ +AV+IEQ + +A Sbjct: 210 KRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEA 269 Query: 315 LPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRVS 374 LPV L+GMN LM QY+EFVADRLLV G K ++ ENPFDFMENISL GKTNFFEKRVS Sbjct: 270 LPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVS 329 Query: 375 DYQKAGVMSKSTKQEAGAFTFNEDF 399 +YQ+ VM+++T FT + DF Sbjct: 330 EYQRFAVMAETTD---NVFTLDADF 351 >4DJN-A nrPDB Length = 311 Score = 435 bits (1118), Expect = e-122, Method: Compositional matrix adjust. Identities = 201/293 (68%), Positives = 244/293 (83%), Gaps = 1/293 (0%) Query: 75 EEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFI 134 EEPLL + R V+FPI+Y +IW+ YK+A+ASFWTAEE+DLSKD+ WN ++ +E++FI Sbjct: 20 EEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWN-KLKADEKYFI 78 Query: 135 SRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDP 194 S +LAFFAASDGIVNENLVE FS EVQ+PEA+ FYGFQI+IEN+HSE YSLLIDTYI+DP Sbjct: 79 SHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDP 138 Query: 195 KESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLK 254 K+ EFLFNAI T+P + +KA+WALRWI D + FGER+VAFA++EGVFFSGSFA+IFWLK Sbjct: 139 KKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLK 198 Query: 255 KRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDA 314 KRG+MPGLTFSNELI RDEGLH DFACL+F +L NKP V +I+ +AV+IEQ + +A Sbjct: 199 KRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEA 258 Query: 315 LPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTN 367 LPV L+GMN LM QY+EFVADRLLV G K ++ ENPFDFMENISL GKTN Sbjct: 259 LPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTN 311 >3OLJ-A nrPDB Length = 286 Score = 422 bits (1085), Expect = e-118, Method: Compositional matrix adjust. Identities = 198/284 (69%), Positives = 234/284 (82%), Gaps = 1/284 (0%) Query: 74 KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFF 133 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + + ER+F Sbjct: 4 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWES-LKPEERYF 62 Query: 134 ISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKD 193 IS VLAFFAASDGIVNENLVE FS EVQI EA+ FYGFQI +ENIHSE YSLLIDTYIKD Sbjct: 63 ISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKD 122 Query: 194 PKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWL 253 PKE EFLFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSFASIFWL Sbjct: 123 PKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWL 182 Query: 254 KKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLD 313 KKRG+MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+ AV IEQ + + Sbjct: 183 KKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTE 242 Query: 314 ALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFM 357 ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFM Sbjct: 243 ALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFM 286 >1SMS-A nrPDB Length = 345 Score = 399 bits (1025), Expect = e-111, Method: Compositional matrix adjust. Identities = 189/347 (54%), Positives = 257/347 (74%), Gaps = 3/347 (0%) Query: 53 ENHKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEE 112 E H +LK+ Q RH +KE EK+E LL E+ R V+FPIKYHEIW AYK+ EASFWTAEE Sbjct: 2 EAHNQFLKTFQKERHDMKEAEKDEILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEE 61 Query: 113 IDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQ 172 I+L+KD D+ ++ ++++ +I +LA +SD +VN+ L+ENFS ++Q PE KSFYGFQ Sbjct: 62 IELAKDTEDFQ-KLTDDQKTYIGNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQ 120 Query: 173 IMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERL 232 IM+ENI+SE YS+++D + KDPK LF I +PE+ KA + RWI + D+L+ ERL Sbjct: 121 IMMENIYSEVYSMMVDAFFKDPKNIP-LFKEIANLPEVKHKAAFIERWISNDDSLYAERL 179 Query: 233 VAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPD 292 VAFA+ EG+F +G++AS+FWL + +MPGL +N ICRD G +TDF+CLLFAHL+ KP+ Sbjct: 180 VAFAAKEGIFQAGNYASMFWLTDKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPN 239 Query: 293 PAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVEN 352 P I+EKI+TEAVEIE+ Y+ ++LPV GM+ ++ Y+EFVAD LL FGN+KYY N Sbjct: 240 PKIIEKIITEAVEIEKEYYSNSLPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVN 299 Query: 353 PFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 PF+FME+++ AGKT FFEK+VSDYQKA MSKS + F++DF Sbjct: 300 PFEFMEDVATAGKTTFFEKKVSDYQKASDMSKSA-TPSKEINFDDDF 345 >2P1I-A nrPDB Length = 349 Score = 386 bits (991), Expect = e-107, Method: Compositional matrix adjust. Identities = 193/330 (58%), Positives = 241/330 (73%), Gaps = 5/330 (1%) Query: 70 KEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNEN 129 K E E +LN++ R L PI Y E+W YK+AEASFWTAEEIDLS D+ D+ ++N N Sbjct: 25 KSKESNEKILNKESNRFTLHPIMYPEVWNFYKKAEASFWTAEEIDLSSDLKDFE-KLNVN 83 Query: 130 ERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDT 189 E+ FI VLAFFAASDGIV ENL F EV+I EAK FY FQI +ENIHSETYSLLID Sbjct: 84 EKHFIKHVLAFFAASDGIVLENLASKFLREVEIIEAKKFYSFQIAVENIHSETYSLLIDN 143 Query: 190 YIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFAS 249 YIKD KE LF+AI IP I KA WA +WI D ++ F ER+VA A +EG+ FSGSF + Sbjct: 144 YIKDEKERLNLFHAIENIPAIKNKALWAAKWINDTNS-FAERIVANACVEGILFSGSFCA 202 Query: 250 IFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQR 309 IFW KK+ + GLTFSNELI RDEGLHTDF CL+++ L+NK +V+ IV EAVE+E+ Sbjct: 203 IFWFKKQNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPENVVQNIVKEAVEVERS 262 Query: 310 YFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFF 369 + ++LP L+GMN+ LM+QY+EFVADRLL G K + +NPF++M+ ISL GKTNFF Sbjct: 263 FICESLPCDLIGMNSRLMSQYIEFVADRLLECLGCSKVFHSKNPFNWMDLISLQGKTNFF 322 Query: 370 EKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 EKRV+DYQK+GVM++ +Q F+ N DF Sbjct: 323 EKRVADYQKSGVMAQRKEQ---VFSLNTDF 349 >2O1Z-A nrPDB Length = 311 Score = 337 bits (865), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 164/289 (56%), Positives = 214/289 (74%), Gaps = 2/289 (0%) Query: 70 KEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNEN 129 K E E +L+++ +R L+PI Y ++W YK+AEASFWTAEEIDLS D+ D+ ++N+N Sbjct: 24 KSKEANEKILSKETDRFTLYPILYPDVWDFYKKAEASFWTAEEIDLSSDLKDFE-KLNDN 82 Query: 130 ERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDT 189 E+ FI VLAFFAASDGIV ENL F +V+I EAK FY FQI +ENIHSETYSLLID Sbjct: 83 EKHFIKHVLAFFAASDGIVLENLASKFLRQVKITEAKKFYAFQIAVENIHSETYSLLIDN 142 Query: 190 YIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFAS 249 YIKD KE LF+AI IP + KA WA +WI D ++ F ER+VA A +EG+ FSGSF + Sbjct: 143 YIKDEKERMNLFHAIENIPAVKNKALWAAKWINDTNS-FAERIVANACVEGILFSGSFCA 201 Query: 250 IFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQR 309 IFW KK+ + GLTFSNELI RDEGLHTDF CL+++ L+NK +V+ IV EAVE+E+ Sbjct: 202 IFWFKKQNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPEEVVQNIVKEAVEVERS 261 Query: 310 YFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFME 358 + ++LP L+GMN+ LM+QY+EFVADRLL G+ K + +NPF++M+ Sbjct: 262 FICESLPCDLIGMNSRLMSQYIEFVADRLLECLGSPKIFHAKNPFNWMD 310 >4M1I-A nrPDB Length = 366 Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 100/319 (31%), Positives = 157/319 (49%), Gaps = 27/319 (8%) Query: 88 LFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDW-NNRMNENERFFISRVLAFFAASDG 146 L PIKY W+ Y A+ W EI + KDI W ++R++E+ER I L FF+ ++ Sbjct: 51 LVPIKYKWAWEHYLNGCANNWLPTEIPMGKDIELWKSDRLSEDERRVILLNLGFFSTAES 110 Query: 147 IVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHT 206 +V N+V V PEA+ + Q E +H+ T+ + ++ D KE +FNA + Sbjct: 111 LVGNNIVLAIFKHVTNPEARQYLLRQAFEEAVHTHTFLYICESLGLDEKE---IFNAYNE 167 Query: 207 IPEIGEKAEWALRWIQDA-------DAL-----FGERLVAFASI-EGVFFSGSFASIFWL 253 I K ++ + D++ F + LV + I EG+FF F I Sbjct: 168 RAAIKAKDDFQMEITGKVLDPNFRTDSVEGLQEFVKNLVGYYIIMEGIFFYSGFVMILSF 227 Query: 254 KKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAI--------VEKIVTEAVE 305 ++ M G+ + I RDE +H +F L +K + +P I + +++ AV+ Sbjct: 228 HRQNKMIGIGEQYQYILRDETIHLNFGIDLINGIKEE-NPEIWTPELQQEIVELIKRAVD 286 Query: 306 IEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFM-ENISLAG 364 +E Y D LP +LG+ A + YV+ +ADR L G K Y +NPF +M E I L Sbjct: 287 LEIEYAQDCLPRGILGLRASMFIDYVQHIADRRLERIGLKPIYHTKNPFPWMSETIDLNK 346 Query: 365 KTNFFEKRVSDYQKAGVMS 383 + NFFE RV +YQ A ++ Sbjct: 347 EKNFFETRVIEYQHAASLT 365 >2RCC-A nrPDB Length = 346 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 71/309 (22%), Positives = 141/309 (45%), Gaps = 25/309 (8%) Query: 91 IKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNE 150 +++ + YK A+FWT EI++S D + + E E+ +++ A D + + Sbjct: 36 VRFSWAYPLYKNMLANFWTPFEINMSHDAKQFPT-LTETEQEAFKKIIGLLAFLDSVQTD 94 Query: 151 NLVE--NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIP 208 + + T+ + S FQ E +H+++YS ++ + + + E +F Sbjct: 95 YSMRAAEYLTDSSLAALMSVLSFQ---EVVHNQSYSYVLSSLVPKATQDE-IFEYWKHDD 150 Query: 209 EIGEKAEWAL----RWIQDADA-LFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLT 263 + E+ E+ + +++ + F E +V +EG+ F FA + L + M + Sbjct: 151 VLKERNEFIIDGYEKFVDNPTPKTFLESIVYDVILEGLNFYSGFAFFYNLARNQKMVSTS 210 Query: 264 FSNELICRDEGLHTD-----FACLL--FAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALP 316 I RDE LH F LL F L + V+ + +A ++E+ +F + Sbjct: 211 TMINYINRDEQLHVYLFTNIFKELLVEFPELNTEETKTFVKTTLMKAADLEKDWFRYIIG 270 Query: 317 VALLGMNADLMNQYVEFVADRLLVAFGNKKYYK--VENPFDFM---ENISLAGKTNFFEK 371 + G+N + M Y+ F+A++ V G +K Y NP ++ E+++ +GK++FFE+ Sbjct: 271 DKIPGINPEDMETYISFIANKRAVQLGMEKPYPEIKHNPMKWIRAYEDVN-SGKSDFFEQ 329 Query: 372 RVSDYQKAG 380 + Y K Sbjct: 330 KSRQYAKVS 338 >1PIY-A nrPDB Length = 375 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 66/278 (23%), Positives = 112/278 (40%), Gaps = 45/278 (16%) Query: 107 FWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAK 166 FW EE+D+S+D D+ + FIS L + D I + + IPE + Sbjct: 47 FWRPEEVDVSRDRIDYQALPEHEKHIFISN-LKYQTLLDSIQGRSPNVALLPLISIPELE 105 Query: 167 SFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADA 226 ++ E IHS +Y+ +I + DP +F+ I T +I ++AE + + Sbjct: 106 TWVETWAFSETIHSRSYTHIIRNIVNDPS---VVFDDIVTNEQIQKRAEGISSYYDELIE 162 Query: 227 ------LFGER-----------------------LVAFASIEGVFFSGSFASIFWLKKRG 257 L GE L++ ++E + F SFA F +R Sbjct: 163 MTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERE 222 Query: 258 MMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPV 317 +M G LI RDE LH + L++ D + +I E + F+ A Sbjct: 223 LMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQ 282 Query: 318 ------------ALLGMNADLMNQYVEFVADRLLVAFG 343 +++G+N D++ QYVE++ + + A G Sbjct: 283 EKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVG 320 >4DR0-A nrPDB Length = 350 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 70/297 (23%), Positives = 139/297 (46%), Gaps = 21/297 (7%) Query: 100 YKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTE 159 Y + FW EEI L+ D+ W + +NE+ +VLA D + + Sbjct: 43 YNQNVKQFWLPEEIALNGDLLTW-KYLGKNEQDTYMKVLAGLTLLDTEQGNTGMPIVAEH 101 Query: 160 VQIPEAKSFYGFQIMIEN-IHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWAL 218 V + K+ F M+EN +H+++YS + T +E +F + + +KA+ + Sbjct: 102 VDGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINE-VFEWVKQNKYLQKKAQMIV 160 Query: 219 ---RWIQDAD--ALFGERLVAFASIEG-VFFSGSFASIFWLKKRGMMPGLTFSNELICRD 272 + IQ D +LF + +VA +E +F+SG + +++ + +M N LI RD Sbjct: 161 GLYKAIQKDDEISLF-KAMVASVYLESFLFYSGFYYPLYFYGQGKLMQSGEIIN-LILRD 218 Query: 273 EGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVA-----LLGMNADLM 327 E +H + LL + NK ++ A+++ + + + L +G++ D+ Sbjct: 219 EAIHGVYVGLLAQEIYNKQTEEKKAELREFAIDLLNQLYENELEYTEDLYDQVGLSHDV- 277 Query: 328 NQYVEFVADRLLVAFGNKKYYKVE--NPFDFMENISLAGKT-NFFEKRVSDYQKAGV 381 +++ + A++ L+ G Y++ E NP + ++ K+ +FF + + Y+KA V Sbjct: 278 KKFIRYNANKALMNLGFDPYFEEEDINPI-VLNGLNTKTKSHDFFSMKGNGYKKATV 333 >4N83-A nrPDB Length = 319 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 43/187 (22%), Positives = 89/187 (47%), Gaps = 6/187 (3%) Query: 99 AYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFST 158 +++ FW I LS D+ DW +++ E+ + +V D + +E+ V+ Sbjct: 21 TWEKLTEQFWLDTRIPLSNDLDDWR-KLSHKEKDLVGKVFGGLTLLDTLQSESGVDALRK 79 Query: 159 EVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWAL 218 +V+ ++ + +E++H+++YS + T + E + +F +T P + +KAE Sbjct: 80 DVRTAHEEAVFNNIQFMESVHAKSYSSIFST-LNTKSEIDEIFAWTNTNPYLQKKAEIIN 138 Query: 219 RWIQDADALFGERLVAFASIEG-VFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHT 277 + AL E+ +A +E +F+SG F +++L + + +LI RDE +H Sbjct: 139 EIYLNGTAL--EKKIASVFLETFLFYSGFFTPLYYLGNN-KLANVAEIIKLIIRDESVHG 195 Query: 278 DFACLLF 284 + F Sbjct: 196 TYIGYKF 202 >4BMQ-A nrPDB Length = 322 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 73/313 (23%), Positives = 135/313 (43%), Gaps = 25/313 (7%) Query: 100 YKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTE 159 +K+ A FWT EEI +S D + W ++++ E+ RVL D + Sbjct: 18 WKQNIAQFWTEEEIAVSSDKNTW-VQLSKEEQIAYKRVLGGLTLLDTKQGGEGMPLVLVH 76 Query: 160 VQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALR 219 ++ +AKS F +E +H+++YS + T + +E + +F+ + P + +KA Sbjct: 77 LENLQAKSVLAFMGAMEEVHAKSYSHIFTT-LATEEEIDDIFDWVDNHPLLEKKAGIITS 135 Query: 220 WIQ-------DADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRD 272 + + L+ +VA +E F F +L +G + LI RD Sbjct: 136 YYRRLLKPEVTKKELY-MAMVASVFLESYLFYSGFFYPLYLAGQGKLTASGEIINLIIRD 194 Query: 273 EGLHTDFACLL----FAHLKNKPDPAI---VEKIVTEAVEIEQRYFLDALPVALLGMNAD 325 E +H F +L FA L + + ++++ E EIE Y + +G+ D Sbjct: 195 ESIHGVFVGILAQQIFAELSAEEQQEVQKETQELLMELYEIEMAYTEEIYTS--IGLVED 252 Query: 326 LMNQYVEFVADRLLVAFGNKKYYKVE--NPFDFMENISLAGKTNFFEKRVSDYQKAGVMS 383 + N++V + A++ L+ G + ++ E NP + +FF + + Y KA + Sbjct: 253 V-NRFVRYNANKGLMNLGLEPKFEEEEINPIVLNGLRTDTKNHDFFSVKGNGYVKATNVE 311 Query: 384 KSTKQEAGAFTFN 396 K + F FN Sbjct: 312 KLADDD---FVFN 321 >3MJO-A nrPDB Length = 296 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 44/182 (24%), Positives = 74/182 (40%), Gaps = 7/182 (3%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVE 154 E+W R +FW E+I +S DI W N+M E+ RV D I Sbjct: 30 EVWD---RLTGNFWLPEKIPVSNDIQSW-NKMTPQEQLATMRVFTGLTLLDTIQGTVGAI 85 Query: 155 NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKA 214 + + + ++ Y +E++H+++YS + T P+ +E F + KA Sbjct: 86 SLLPDAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINE-AFRWSEENENLQRKA 144 Query: 215 EWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEG 274 + + + D L ++ VA +E F F +L R + LI RDE Sbjct: 145 KIIMSYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDES 202 Query: 275 LH 276 +H Sbjct: 203 VH 204 >3DHZ-A nrPDB Length = 329 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 44/182 (24%), Positives = 74/182 (40%), Gaps = 7/182 (3%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVE 154 E+W R +FW E+I +S DI W N+M E+ RV D I Sbjct: 31 EVWD---RLTGNFWLPEKIPVSNDIQSW-NKMTPQEQLATMRVFTGLTLLDTIQGTVGAI 86 Query: 155 NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKA 214 + + + ++ Y +E++H+++YS + T P+ +E F + KA Sbjct: 87 SLLPDAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINE-AFRWSEENENLQRKA 145 Query: 215 EWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEG 274 + + + D L ++ VA +E F F +L R + LI RDE Sbjct: 146 KIIMSYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDES 203 Query: 275 LH 276 +H Sbjct: 204 VH 205 >1UZR-A nrPDB Length = 296 Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 43/183 (23%), Positives = 76/183 (41%), Gaps = 9/183 (4%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVE 154 E+W R +FW E++ +S DI W + E+ RV D I Sbjct: 26 EVWD---RLTGNFWLPEKVPVSNDIPSWGT-LTAGEKQLTMRVFTGLTMLDTIQGTVGAV 81 Query: 155 NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKA 214 + + P ++ +E++H+++YS + T + E + F + KA Sbjct: 82 SLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFST-LCSTAEIDDAFRWSEENRNLQRKA 140 Query: 215 EWALRWIQDADALFGERLVAFASIEG-VFFSGSFASIFWLKKRGMMPGLTFSNELICRDE 273 E L+ + + L +R VA +E +F+SG + ++W R + LI RDE Sbjct: 141 EIVLQSYRGDEPL--KRKVASTLLESFLFYSGFYLPMYW-SSRAKLTNTADMIRLIIRDE 197 Query: 274 GLH 276 +H Sbjct: 198 AVH 200 >6GP2-A nrPDB Length = 345 Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 51/225 (22%), Positives = 90/225 (40%), Gaps = 16/225 (7%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGI-VNENLV 153 E+W R +FW E+I +S D+ W E + I+R D I V Sbjct: 47 EVWN---RITQNFWLPEKIPVSNDLTSWRTLTPEWQEL-ITRTFTGLTLLDTIQATVGDV 102 Query: 154 ENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEK 213 + E + F M+ +H+ ++ + T + E I+T + E+ Sbjct: 103 AQVPNSLTDHEQVIYTNFAFMVA-VHARSFGSIFSTLCSSEQIEEAHEWVINT-ETLQER 160 Query: 214 AEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDE 273 A+ + + + D L + VA A + G G F F+L RG +P + LI RD+ Sbjct: 161 AKALIPYYVNDDPL--KSKVAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDK 218 Query: 274 GLHTDFACLLFAHLKNKPDP-------AIVEKIVTEAVEIEQRYF 311 +H ++ + K P V K++ E +++E+ Y Sbjct: 219 VIHNYYSGYKYQKKVAKLSPEKQAEMKEFVFKLLYELIDLEKAYL 263 >2BQ1-I nrPDB Length = 319 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 42/182 (23%), Positives = 72/182 (39%), Gaps = 7/182 (3%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVE 154 E+W R ++FW E++ LS DI W ++ E+ RV D I N Sbjct: 21 EVWN---RLTSNFWLPEKVPLSNDIPAWQT-LSAAEQQLTIRVFTGLTLLDTIQNIAGAP 76 Query: 155 NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKA 214 + + P ++ +E +H+ +YS + T + KE + + P + KA Sbjct: 77 SLMADAITPHEEAVLSNISFMEAVHARSYSSIFSTLCQT-KEVDAAYAWSEENPPLQRKA 135 Query: 215 EWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEG 274 + L + L ++ +A +E F F + RG + LI RDE Sbjct: 136 QIILAHYVSDEPL--KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEA 193 Query: 275 LH 276 +H Sbjct: 194 VH 195 >6EBP-A nrPDB Length = 355 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 44/195 (22%), Positives = 75/195 (38%), Gaps = 33/195 (16%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNE-NLV 153 E+W R +FW E I +S D+ WN ++++ + I+R D + + V Sbjct: 57 EVW---NRVTQNFWLPENIPVSNDLPSWN-ELDDDWQQLITRTFTGLTLLDTVQSSIGDV 112 Query: 154 ENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEK 213 + E + F M+ +H+ ++ + F+ + T +I E Sbjct: 113 AQIKNSLTEQEQVIYANFAFMV-GVHARSFGTI--------------FSTLCTSEQIEEA 157 Query: 214 AEW------------ALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPG 261 EW AL AD ++ A A + G G F F+L RG +P Sbjct: 158 HEWVVDNEALQARPKALIPFYTADDPLKSKIAA-ALMPGFLLYGGFYLPFYLSARGKLPN 216 Query: 262 LTFSNELICRDEGLH 276 + LI RD+ +H Sbjct: 217 TSDIIRLILRDKVIH 231 >6QRZ-A nrPDB Length = 328 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 51/216 (23%), Positives = 90/216 (41%), Gaps = 34/216 (15%) Query: 89 FPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASD--- 145 FP+K ++I + FW +ID SKD DW +++++E+ ++ +++ F A + Sbjct: 44 FPMKLYQI------GKRLFWDPAKIDFSKDKEDW-KKLSKDEKNYLLNIVSLFMAGEEAV 96 Query: 146 ---------GIVNENLVEN--FSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDP 194 ++NE VE+ + + EAK F+ +++ L I T +P Sbjct: 97 AVDITPLISTMINEGRVEDVIYLEQFAFEEAKHAEAFRRFCDSLEIND-DLTIFTTEYNP 155 Query: 195 KESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFF-SG--SFASIF 251 + + + ++ W LR + L +EGV SG +F IF Sbjct: 156 WYQKIFYEELPSV-------MWKLRVDPSPENLAVAVTTYNLYVEGVAAESGYKTFKHIF 208 Query: 252 WLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHL 287 +MPGL+ + LI DE H + L L Sbjct: 209 --NSLNIMPGLSKTVNLIATDESRHIAYGTYLITRL 242 >3N37-A nrPDB Length = 319 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 39/182 (21%), Positives = 71/182 (39%), Gaps = 7/182 (3%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVE 154 E+W R ++FW E++ LS DI W + E+ RV D + N Sbjct: 21 EVWN---RLTSNFWLPEKVPLSNDIPAWQT-LTVVEQQLTMRVFTGLTLLDTLQNVIGAP 76 Query: 155 NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKA 214 + + P ++ +E +H+ +YS + T + K+ + + + KA Sbjct: 77 SLMPDALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQT-KDVDAAYAWSEENAPLQRKA 135 Query: 215 EWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEG 274 + + + D L ++ +A +E F F + RG + LI RDE Sbjct: 136 QIIQQHYRGDDPL--KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEA 193 Query: 275 LH 276 +H Sbjct: 194 VH 195 >4AC8-A nrPDB Length = 323 Score = 34.3 bits (77), Expect = 0.10, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 1/48 (2%) Query: 105 ASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENL 152 A FW +ID ++D DW +++++ER + +R+ F A + V E++ Sbjct: 38 AKFWHPADIDFTRDRADW-EKLSDDERDYATRLCTQFIAGEEAVTEDI 84 >6CWO-A nrPDB Length = 344 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 47/234 (20%), Positives = 95/234 (40%), Gaps = 25/234 (10%) Query: 90 PIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVN 149 P +Y E+ Q + ++W E+D + D D++ ++ E+ + L A + V Sbjct: 32 PFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQIEVAVK 91 Query: 150 E---NLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHT 206 N+ E+F PE E HSE YS L++ + + F + Sbjct: 92 SFWGNIYEHFPK----PEFNGLGSTFAECEFRHSEAYSRLLEVLGYNDE-----FEKLLD 142 Query: 207 IPEIGEKAEWALRWIQDADAL----FGERLVAFAS-IEGVFFSGSFASIFWLKK-RGMMP 260 +P I + ++ ++D + + L+ F+ IE V FA + + +G M Sbjct: 143 VPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFKGYMK 202 Query: 261 GLTFSNELICRDEGLHTDFACLLFAHLKNK-PD------PAIVEKIVTEAVEIE 307 ++ DE +H + + ++ + PD A+V + V +++ +E Sbjct: 203 NVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVE 256 >6CWP-A nrPDB Length = 307 Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust. Identities = 47/234 (20%), Positives = 95/234 (40%), Gaps = 25/234 (10%) Query: 90 PIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVN 149 P +Y E+ Q + ++W E+D + D D++ ++ E+ + L A + V Sbjct: 19 PFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQIEVAVK 78 Query: 150 E---NLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHT 206 N+ E+F PE E HSE YS L++ + + F + Sbjct: 79 SFWGNIYEHFPK----PEFNGLGSTFAECEFRHSEAYSRLLEVLGYNDE-----FEKLLD 129 Query: 207 IPEIGEKAEWALRWIQDADAL----FGERLVAFAS-IEGVFFSGSFASIFWLKK-RGMMP 260 +P I + ++ ++D + + L+ F+ IE V FA + + +G M Sbjct: 130 VPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFKGYMK 189 Query: 261 GLTFSNELICRDEGLHTDFACLLFAHLKNK-PD------PAIVEKIVTEAVEIE 307 ++ DE +H + + ++ + PD A+V + V +++ +E Sbjct: 190 NVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVE 243 >4WSS-A nrPDB Length = 514 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 24/50 (48%) Query: 165 AKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKA 214 SFY + I I S+ YSL+ TY +S F +H P+ E+A Sbjct: 144 GSSFYRNLLWIIKIRSDPYSLIKGTYTNTGSQSILYFWGVHHPPDDVEQA 193 >6B1L-A nrPDB Length = 405 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 2/62 (3%) Query: 142 AASDGIVNENLVENFST-EVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFL 200 + ++ +++N VE+ E ++P S+Y + E SE Y+LL D Y++D ++ F Sbjct: 41 SVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVED-DDNIFR 99 Query: 201 FN 202 FN Sbjct: 100 FN 101 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1SMQ-A nrPDB 543 e-155 1H0O-A nrPDB 494 e-140 2UW2-A nrPDB 445 e-125 3HF1-A nrPDB 436 e-123 4DJN-A nrPDB 403 e-113 1SMS-A nrPDB 398 e-111 3OLJ-A nrPDB 397 e-111 2P1I-A nrPDB 389 e-108 2O1Z-A nrPDB 349 2e-96 4M1I-A nrPDB 301 4e-82 4BMQ-A nrPDB 268 4e-72 4DR0-A nrPDB 265 3e-71 2RCC-A nrPDB 252 2e-67 2BQ1-I nrPDB 246 8e-66 3DHZ-A nrPDB 243 1e-64 1UZR-A nrPDB 241 4e-64 4N83-A nrPDB 241 5e-64 3MJO-A nrPDB 237 8e-63 6GP2-A nrPDB 235 2e-62 1PIY-A nrPDB 225 2e-59 6EBP-A nrPDB 221 4e-58 6QRZ-A nrPDB 144 5e-35 Sequences not found previously or not previously below threshold: 3N37-A nrPDB 245 3e-65 6CWO-A nrPDB 92 4e-19 5OLK-A nrPDB 88 5e-18 6CWP-A nrPDB 86 3e-17 4AC8-A nrPDB 84 1e-16 5OMK-A nrPDB 76 4e-14 1ZA0-A nrPDB 33 0.25 3Q3N-A nrPDB 32 0.35 3N1X-A nrPDB 32 0.44 3ETC-A nrPDB 32 0.67 1ZVU-A nrPDB 31 0.93 5FTW-A nrPDB 30 1.4 4LHD-A nrPDB 30 1.6 4F7Z-A nrPDB 30 2.1 3CHI-A nrPDB 30 2.3 6MEL-B nrPDB 29 3.0 4MGY-E nrPDB 29 3.0 1ZVD-A nrPDB 29 3.3 1SB7-A nrPDB 29 3.6 5EUT-A nrPDB 29 4.1 2X5F-A nrPDB 29 4.6 5K52-A nrPDB 29 4.7 4HNE-A nrPDB 29 5.1 >1SMQ-A nrPDB Length = 399 Score = 543 bits (1400), Expect = e-155, Method: Composition-based stats. Identities = 399/399 (100%), Positives = 399/399 (100%) Query: 1 MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLK 60 MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLK Sbjct: 1 MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLK 60 Query: 61 SHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIH 120 SHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIH Sbjct: 61 SHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIH 120 Query: 121 DWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHS 180 DWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHS Sbjct: 121 DWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHS 180 Query: 181 ETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEG 240 ETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEG Sbjct: 181 ETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEG 240 Query: 241 VFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIV 300 VFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIV Sbjct: 241 VFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIV 300 Query: 301 TEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENI 360 TEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENI Sbjct: 301 TEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENI 360 Query: 361 SLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 SLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF Sbjct: 361 SLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 >1H0O-A nrPDB Length = 390 Score = 494 bits (1272), Expect = e-140, Method: Composition-based stats. Identities = 237/392 (60%), Positives = 289/392 (73%), Gaps = 21/392 (5%) Query: 25 NLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLK--------EME--- 73 ++ L T+ ++ +++ LK D EN L S +V K E+E Sbjct: 3 SVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELESKA 62 Query: 74 ------KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMN 127 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + Sbjct: 63 PTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEA-LK 121 Query: 128 ENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLI 187 +ER FIS VLAFFAASDGIVNENLVE FS EVQ+ EA+ FYGFQI +ENIHSE YSLLI Sbjct: 122 PDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLI 181 Query: 188 DTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSF 247 DTYIKDPKE E+LFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSF Sbjct: 182 DTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSF 241 Query: 248 ASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIE 307 ASIFWLKKRG+MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+T AV IE Sbjct: 242 ASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIE 301 Query: 308 QRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTN 367 Q + +ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFMENISL GKTN Sbjct: 302 QEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTN 361 Query: 368 FFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 FFEKRV +YQ+ GVMS ST+ +FT + DF Sbjct: 362 FFEKRVGEYQRMGVMSNSTE---NSFTLDADF 390 >2UW2-A nrPDB Length = 332 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 224/326 (68%), Positives = 264/326 (80%), Gaps = 4/326 (1%) Query: 74 KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFF 133 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + + ER+F Sbjct: 11 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWES-LKPEERYF 69 Query: 134 ISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKD 193 IS VLAFFAASDGIVNENLVE FS EVQI EA+ FYGFQI +ENIHSE YSLLIDTYIKD Sbjct: 70 ISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKD 129 Query: 194 PKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWL 253 PKE EFLFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSFASIFWL Sbjct: 130 PKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWL 189 Query: 254 KKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLD 313 KKRG MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+ AV IEQ + + Sbjct: 190 KKRGPMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTE 249 Query: 314 ALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRV 373 ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFMENISL GKTNFFEKRV Sbjct: 250 ALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRV 309 Query: 374 SDYQKAGVMSKSTKQEAGAFTFNEDF 399 +YQ+ GVMS T+ +FT + DF Sbjct: 310 GEYQRMGVMSSPTE---NSFTLDADF 332 >3HF1-A nrPDB Length = 351 Score = 436 bits (1121), Expect = e-123, Method: Composition-based stats. Identities = 217/328 (66%), Positives = 266/328 (81%), Gaps = 4/328 (1%) Query: 72 MEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENER 131 EEPLL + R V+FPI+Y +IW+ YK+A+ASFWTAEE+DLSKD+ WN ++ +E+ Sbjct: 28 KSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWN-KLKADEK 86 Query: 132 FFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYI 191 +FIS +LAFFAASDGIVNENLVE FS EVQ+PEA+ FYGFQI+IEN+HSE YSLLIDTYI Sbjct: 87 YFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYI 146 Query: 192 KDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIF 251 +DPK+ EFLFNAI T+P + +KA+WALRWI D + FGER+VAFA++EGVFFSGSFA+IF Sbjct: 147 RDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIF 206 Query: 252 WLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYF 311 WLKKRG+MPGLTFSNELI RDEGLH DFACL+F +L NKP V +I+ +AV+IEQ + Sbjct: 207 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFL 266 Query: 312 LDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEK 371 +ALPV L+GMN LM QY+EFVADRLLV G K ++ ENPFDFMENISL GKTNFFEK Sbjct: 267 TEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEK 326 Query: 372 RVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 RVS+YQ+ VM+++T FT + DF Sbjct: 327 RVSEYQRFAVMAETTD---NVFTLDADF 351 >4DJN-A nrPDB Length = 311 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 201/296 (67%), Positives = 244/296 (82%), Gaps = 1/296 (0%) Query: 72 MEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENER 131 EEPLL + R V+FPI+Y +IW+ YK+A+ASFWTAEE+DLSKD+ WN ++ +E+ Sbjct: 17 KSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWN-KLKADEK 75 Query: 132 FFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYI 191 +FIS +LAFFAASDGIVNENLVE FS EVQ+PEA+ FYGFQI+IEN+HSE YSLLIDTYI Sbjct: 76 YFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYI 135 Query: 192 KDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIF 251 +DPK+ EFLFNAI T+P + +KA+WALRWI D + FGER+VAFA++EGVFFSGSFA+IF Sbjct: 136 RDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIF 195 Query: 252 WLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYF 311 WLKKRG+MPGLTFSNELI RDEGLH DFACL+F +L NKP V +I+ +AV+IEQ + Sbjct: 196 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFL 255 Query: 312 LDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTN 367 +ALPV L+GMN LM QY+EFVADRLLV G K ++ ENPFDFMENISL GKTN Sbjct: 256 TEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTN 311 >1SMS-A nrPDB Length = 345 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 189/347 (54%), Positives = 257/347 (74%), Gaps = 3/347 (0%) Query: 53 ENHKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEE 112 E H +LK+ Q RH +KE EK+E LL E+ R V+FPIKYHEIW AYK+ EASFWTAEE Sbjct: 2 EAHNQFLKTFQKERHDMKEAEKDEILLMENSRRFVMFPIKYHEIWAAYKKVEASFWTAEE 61 Query: 113 IDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQ 172 I+L+KD D+ ++ ++++ +I +LA +SD +VN+ L+ENFS ++Q PE KSFYGFQ Sbjct: 62 IELAKDTEDFQ-KLTDDQKTYIGNLLALSISSDNLVNKYLIENFSAQLQNPEGKSFYGFQ 120 Query: 173 IMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERL 232 IM+ENI+SE YS+++D + KDPK LF I +PE+ KA + RWI + D+L+ ERL Sbjct: 121 IMMENIYSEVYSMMVDAFFKDPKNIP-LFKEIANLPEVKHKAAFIERWISNDDSLYAERL 179 Query: 233 VAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPD 292 VAFA+ EG+F +G++AS+FWL + +MPGL +N ICRD G +TDF+CLLFAHL+ KP+ Sbjct: 180 VAFAAKEGIFQAGNYASMFWLTDKKIMPGLAMANRNICRDRGAYTDFSCLLFAHLRTKPN 239 Query: 293 PAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVEN 352 P I+EKI+TEAVEIE+ Y+ ++LPV GM+ ++ Y+EFVAD LL FGN+KYY N Sbjct: 240 PKIIEKIITEAVEIEKEYYSNSLPVEKFGMDLKSIHTYIEFVADGLLQGFGNEKYYNAVN 299 Query: 353 PFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 PF+FME+++ AGKT FFEK+VSDYQKA MSKS + F++DF Sbjct: 300 PFEFMEDVATAGKTTFFEKKVSDYQKASDMSKSA-TPSKEINFDDDF 345 >3OLJ-A nrPDB Length = 286 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 198/284 (69%), Positives = 234/284 (82%), Gaps = 1/284 (0%) Query: 74 KEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFF 133 ++EPLL E+ R V+FPI+YH+IWQ YK+AEASFWTAEE+DLSKDI W + + ER+F Sbjct: 4 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWES-LKPEERYF 62 Query: 134 ISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKD 193 IS VLAFFAASDGIVNENLVE FS EVQI EA+ FYGFQI +ENIHSE YSLLIDTYIKD Sbjct: 63 ISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKD 122 Query: 194 PKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWL 253 PKE EFLFNAI T+P + +KA+WALRWI D +A +GER+VAFA++EG+FFSGSFASIFWL Sbjct: 123 PKEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWL 182 Query: 254 KKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLD 313 KKRG+MPGLTFSNELI RDEGLH DFACL+F HL +KP V +I+ AV IEQ + + Sbjct: 183 KKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRIEQEFLTE 242 Query: 314 ALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFM 357 ALPV L+GMN LM QY+EFVADRL++ G K ++VENPFDFM Sbjct: 243 ALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFM 286 >2P1I-A nrPDB Length = 349 Score = 389 bits (999), Expect = e-108, Method: Composition-based stats. Identities = 193/330 (58%), Positives = 241/330 (73%), Gaps = 5/330 (1%) Query: 70 KEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNEN 129 K E E +LN++ R L PI Y E+W YK+AEASFWTAEEIDLS D+ D+ ++N N Sbjct: 25 KSKESNEKILNKESNRFTLHPIMYPEVWNFYKKAEASFWTAEEIDLSSDLKDFE-KLNVN 83 Query: 130 ERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDT 189 E+ FI VLAFFAASDGIV ENL F EV+I EAK FY FQI +ENIHSETYSLLID Sbjct: 84 EKHFIKHVLAFFAASDGIVLENLASKFLREVEIIEAKKFYSFQIAVENIHSETYSLLIDN 143 Query: 190 YIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFAS 249 YIKD KE LF+AI IP I KA WA +WI D ++ F ER+VA A +EG+ FSGSF + Sbjct: 144 YIKDEKERLNLFHAIENIPAIKNKALWAAKWINDTNS-FAERIVANACVEGILFSGSFCA 202 Query: 250 IFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQR 309 IFW KK+ + GLTFSNELI RDEGLHTDF CL+++ L+NK +V+ IV EAVE+E+ Sbjct: 203 IFWFKKQNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPENVVQNIVKEAVEVERS 262 Query: 310 YFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFF 369 + ++LP L+GMN+ LM+QY+EFVADRLL G K + +NPF++M+ ISL GKTNFF Sbjct: 263 FICESLPCDLIGMNSRLMSQYIEFVADRLLECLGCSKVFHSKNPFNWMDLISLQGKTNFF 322 Query: 370 EKRVSDYQKAGVMSKSTKQEAGAFTFNEDF 399 EKRV+DYQK+GVM++ +Q F+ N DF Sbjct: 323 EKRVADYQKSGVMAQRKEQ---VFSLNTDF 349 >2O1Z-A nrPDB Length = 311 Score = 349 bits (894), Expect = 2e-96, Method: Composition-based stats. Identities = 164/304 (53%), Positives = 215/304 (70%), Gaps = 2/304 (0%) Query: 56 KAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDL 115 + K + K E E +L+++ +R L+PI Y ++W YK+AEASFWTAEEIDL Sbjct: 10 PIFSKKEKKFSDLQKSKEANEKILSKETDRFTLYPILYPDVWDFYKKAEASFWTAEEIDL 69 Query: 116 SKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMI 175 S D+ D+ ++N+NE+ FI VLAFFAASDGIV ENL F +V+I EAK FY FQI + Sbjct: 70 SSDLKDFE-KLNDNEKHFIKHVLAFFAASDGIVLENLASKFLRQVKITEAKKFYAFQIAV 128 Query: 176 ENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAF 235 ENIHSETYSLLID YIKD KE LF+AI IP + KA WA +WI + F ER+VA Sbjct: 129 ENIHSETYSLLIDNYIKDEKERMNLFHAIENIPAVKNKALWAAKWI-NDTNSFAERIVAN 187 Query: 236 ASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAI 295 A +EG+ FSGSF +IFW KK+ + GLTFSNELI RDEGLHTDF CL+++ L+NK + Sbjct: 188 ACVEGILFSGSFCAIFWFKKQNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPEEV 247 Query: 296 VEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFD 355 V+ IV EAVE+E+ + ++LP L+GMN+ LM+QY+EFVADRLL G+ K + +NPF+ Sbjct: 248 VQNIVKEAVEVERSFICESLPCDLIGMNSRLMSQYIEFVADRLLECLGSPKIFHAKNPFN 307 Query: 356 FMEN 359 +M+ Sbjct: 308 WMDL 311 >4M1I-A nrPDB Length = 366 Score = 301 bits (770), Expect = 4e-82, Method: Composition-based stats. Identities = 99/343 (28%), Positives = 161/343 (46%), Gaps = 34/343 (9%) Query: 72 MEKEEPLLNEDKERTV---------LFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDW 122 ++ ++ +N + +R V L PIKY W+ Y A+ W EI + KDI W Sbjct: 26 LDGKQKRVNLNSKRLVNCNQVDVNQLVPIKYKWAWEHYLNGCANNWLPTEIPMGKDIELW 85 Query: 123 -NNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSE 181 ++R++E+ER I L FF+ ++ +V N+V V PEA+ + Q E +H+ Sbjct: 86 KSDRLSEDERRVILLNLGFFSTAESLVGNNIVLAIFKHVTNPEARQYLLRQAFEEAVHTH 145 Query: 182 TYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADAL------------FG 229 T+ + ++ D KE +FNA + I K ++ + F Sbjct: 146 TFLYICESLGLDEKE---IFNAYNERAAIKAKDDFQMEITGKVLDPNFRTDSVEGLQEFV 202 Query: 230 ERLV-AFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLK 288 + LV + +EG+FF F I ++ M G+ + I RDE +H +F L +K Sbjct: 203 KNLVGYYIIMEGIFFYSGFVMILSFHRQNKMIGIGEQYQYILRDETIHLNFGIDLINGIK 262 Query: 289 NKPDP-------AIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVA 341 + + +++ AV++E Y D LP +LG+ A + YV+ +ADR L Sbjct: 263 EENPEIWTPELQQEIVELIKRAVDLEIEYAQDCLPRGILGLRASMFIDYVQHIADRRLER 322 Query: 342 FGNKKYYKVENPFDFM-ENISLAGKTNFFEKRVSDYQKAGVMS 383 G K Y +NPF +M E I L + NFFE RV +YQ A ++ Sbjct: 323 IGLKPIYHTKNPFPWMSETIDLNKEKNFFETRVIEYQHAASLT 365 >4BMQ-A nrPDB Length = 322 Score = 268 bits (684), Expect = 4e-72, Method: Composition-based stats. Identities = 73/314 (23%), Positives = 134/314 (42%), Gaps = 25/314 (7%) Query: 99 AYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFST 158 +K+ A FWT EEI +S D + W ++++ E+ RVL D + Sbjct: 17 FWKQNIAQFWTEEEIAVSSDKNTW-VQLSKEEQIAYKRVLGGLTLLDTKQGGEGMPLVLV 75 Query: 159 EVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWAL 218 ++ +AKS F +E +H+++YS + T +E + +F+ + P + +KA Sbjct: 76 HLENLQAKSVLAFMGAMEEVHAKSYSHIFTTLA-TEEEIDDIFDWVDNHPLLEKKAGIIT 134 Query: 219 RWIQ-------DADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICR 271 + + L+ +VA +E F F +L +G + LI R Sbjct: 135 SYYRRLLKPEVTKKELY-MAMVASVFLESYLFYSGFFYPLYLAGQGKLTASGEIINLIIR 193 Query: 272 DEGLHTDFACLL----FAHLKNKPDPAI---VEKIVTEAVEIEQRYFLDALPVALLGMNA 324 DE +H F +L FA L + + ++++ E EIE Y + +G+ Sbjct: 194 DESIHGVFVGILAQQIFAELSAEEQQEVQKETQELLMELYEIEMAYTEEIYTS--IGLVE 251 Query: 325 DLMNQYVEFVADRLLVAFGNKKYYKVE--NPFDFMENISLAGKTNFFEKRVSDYQKAGVM 382 D+ N++V + A++ L+ G + ++ E NP + +FF + + Y KA + Sbjct: 252 DV-NRFVRYNANKGLMNLGLEPKFEEEEINPIVLNGLRTDTKNHDFFSVKGNGYVKATNV 310 Query: 383 SKSTKQEAGAFTFN 396 K + F FN Sbjct: 311 EKLADDD---FVFN 321 >4DR0-A nrPDB Length = 350 Score = 265 bits (677), Expect = 3e-71, Method: Composition-based stats. Identities = 65/312 (20%), Positives = 129/312 (41%), Gaps = 19/312 (6%) Query: 99 AYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFST 158 Y + FW EEI L+ D+ W + +NE+ +VLA D + + Sbjct: 42 FYNQNVKQFWLPEEIALNGDLLTW-KYLGKNEQDTYMKVLAGLTLLDTEQGNTGMPIVAE 100 Query: 159 EVQIPEAKSFYGFQIMIEN-IHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWA 217 V + K+ F M+EN +H+++YS + T +E +F + + +KA+ Sbjct: 101 HVDGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINE-VFEWVKQNKYLQKKAQMI 159 Query: 218 LRWIQ----DADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDE 273 + + D + + +VA +E F F + +G + LI RDE Sbjct: 160 VGLYKAIQKDDEISLFKAMVASVYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDE 219 Query: 274 GLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALP-----VALLGMNADLMN 328 +H + LL + NK ++ A+++ + + + L +G++ D+ Sbjct: 220 AIHGVYVGLLAQEIYNKQTEEKKAELREFAIDLLNQLYENELEYTEDLYDQVGLSHDV-K 278 Query: 329 QYVEFVADRLLVAFGNKKYYKVE--NPFDFMENISLAGKTNFFEKRVSDYQKAGVMSKST 386 +++ + A++ L+ G Y++ E NP + +FF + + Y+KA V Sbjct: 279 KFIRYNANKALMNLGFDPYFEEEDINPIVLNGLNTKTKSHDFFSMKGNGYKKATV-EPLK 337 Query: 387 KQEAGAFTFNED 398 + F F ++ Sbjct: 338 DDD---FYFEDE 346 >2RCC-A nrPDB Length = 346 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 71/309 (22%), Positives = 141/309 (45%), Gaps = 25/309 (8%) Query: 91 IKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNE 150 +++ + YK A+FWT EI++S D + + E E+ +++ A D + + Sbjct: 36 VRFSWAYPLYKNMLANFWTPFEINMSHDAKQFPT-LTETEQEAFKKIIGLLAFLDSVQTD 94 Query: 151 NLVEN--FSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIP 208 + + T+ + S FQ E +H+++YS ++ + + + E +F Sbjct: 95 YSMRAAEYLTDSSLAALMSVLSFQ---EVVHNQSYSYVLSSLVPKATQDE-IFEYWKHDD 150 Query: 209 EIGEKAEWAL----RWIQDADA-LFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLT 263 + E+ E+ + +++ + F E +V +EG+ F FA + L + M + Sbjct: 151 VLKERNEFIIDGYEKFVDNPTPKTFLESIVYDVILEGLNFYSGFAFFYNLARNQKMVSTS 210 Query: 264 FSNELICRDEGLHTD-----FACLL--FAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALP 316 I RDE LH F LL F L + V+ + +A ++E+ +F + Sbjct: 211 TMINYINRDEQLHVYLFTNIFKELLVEFPELNTEETKTFVKTTLMKAADLEKDWFRYIIG 270 Query: 317 VALLGMNADLMNQYVEFVADRLLVAFGNKKYYKV--ENPFDFM---ENISLAGKTNFFEK 371 + G+N + M Y+ F+A++ V G +K Y NP ++ E+++ +GK++FFE+ Sbjct: 271 DKIPGINPEDMETYISFIANKRAVQLGMEKPYPEIKHNPMKWIRAYEDVN-SGKSDFFEQ 329 Query: 372 RVSDYQKAG 380 + Y K Sbjct: 330 KSRQYAKVS 338 >2BQ1-I nrPDB Length = 319 Score = 246 bits (629), Expect = 8e-66, Method: Composition-based stats. Identities = 60/308 (19%), Positives = 115/308 (37%), Gaps = 19/308 (6%) Query: 98 QAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFS 157 + + R ++FW E++ LS DI W ++ E+ RV D I N + Sbjct: 21 EVWNRLTSNFWLPEKVPLSNDIPAWQT-LSAAEQQLTIRVFTGLTLLDTIQNIAGAPSLM 79 Query: 158 TEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWA 217 + P ++ +E +H+ +YS + T + KE + + P + KA+ Sbjct: 80 ADAITPHEEAVLSNISFMEAVHARSYSSIFSTLCQT-KEVDAAYAWSEENPPLQRKAQII 138 Query: 218 LRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHT 277 L + L ++ +A +E F F + RG + LI RDE +H Sbjct: 139 LAHYVSDEPL--KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHG 196 Query: 278 DFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVA-----LLGMNADLMNQYVE 332 + + K E++ A+++ + + + G D+ ++ Sbjct: 197 YYIGYKYQIALQKLSAIEREELKLFALDLLMELYDNEIRYTEALYAETGWVNDV-KAFLC 255 Query: 333 FVADRLLVAFGNKKYYKVE----NPFDFMENI-SLAGKTNFFEKRVSDYQKAGVMSKSTK 387 + A++ L+ G + + E NP + +FF S Y VM K+ + Sbjct: 256 YNANKALMNLGYEALFPPEMADVNPAILAALSPNADENHDFFSGSGSSY----VMGKTVE 311 Query: 388 QEAGAFTF 395 E + F Sbjct: 312 TEDEDWNF 319 >3N37-A nrPDB Length = 319 Score = 245 bits (625), Expect = 3e-65, Method: Composition-based stats. Identities = 58/307 (18%), Positives = 114/307 (37%), Gaps = 17/307 (5%) Query: 98 QAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFS 157 + + R ++FW E++ LS DI W + E+ RV D + N + Sbjct: 21 EVWNRLTSNFWLPEKVPLSNDIPAWQT-LTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLM 79 Query: 158 TEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWA 217 + P ++ +E +H+ +YS + T + K+ + + + KA+ Sbjct: 80 PDALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQT-KDVDAAYAWSEENAPLQRKAQII 138 Query: 218 LRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHT 277 + + D L ++ +A +E F F + RG + LI RDE +H Sbjct: 139 QQHYRGDDPL--KKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHG 196 Query: 278 DFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPV--ALLGMNA--DLMNQYVEF 333 + + K E++ + A ++ + + L L D + ++ + Sbjct: 197 YYIGYKYQKNMEKISLGQREELKSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCY 256 Query: 334 VADRLLVAFGNKKYYKVE----NPFDFMENI-SLAGKTNFFEKRVSDYQKAGVMSKSTKQ 388 A++ L+ G + + E NP + +FF S Y VM K+ + Sbjct: 257 NANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSGSSY----VMGKAVET 312 Query: 389 EAGAFTF 395 E + F Sbjct: 313 EDEDWNF 319 >3DHZ-A nrPDB Length = 329 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 58/302 (19%), Positives = 112/302 (37%), Gaps = 16/302 (5%) Query: 98 QAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFS 157 + + R +FW E+I +S DI WN +M E+ RV D I + Sbjct: 31 EVWDRLTGNFWLPEKIPVSNDIQSWN-KMTPQEQLATMRVFTGLTLLDTIQGTVGAISLL 89 Query: 158 TEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWA 217 + + ++ Y +E++H+++YS + T P+ +E F + KA+ Sbjct: 90 PDAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINEA-FRWSEENENLQRKAKII 148 Query: 218 LRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHT 277 + + D L ++ VA +E F F +L R + LI RDE +H Sbjct: 149 MSYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDESVHG 206 Query: 278 DFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVAL-----LGMNADLMNQYVE 332 + + K A E+ ++ + + + LG D+ +++ Sbjct: 207 YYIGYKYQQGVKKLSEAEQEEYKAYTFDLMYDLYENEIEYTEDIYDDLGWTEDV-KRFLR 265 Query: 333 FVADRLLVAFGNKKYYKVE----NPFDFMENI-SLAGKTNFFEKRVSDYQKAGVMSKSTK 387 + A++ L G + + + +P + +FF S Y G +T Sbjct: 266 YNANKALNNLGYEGLFPTDETKVSPAILSSLSPNADENHDFFSGSGSSYV-IGKAEDTTD 324 Query: 388 QE 389 + Sbjct: 325 DD 326 >1UZR-A nrPDB Length = 296 Score = 241 bits (614), Expect = 4e-64, Method: Composition-based stats. Identities = 51/262 (19%), Positives = 97/262 (37%), Gaps = 17/262 (6%) Query: 95 EIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVE 154 E+W R +FW E++ +S DI W + E+ RV D I Sbjct: 26 EVWD---RLTGNFWLPEKVPVSNDIPSWGT-LTAGEKQLTMRVFTGLTMLDTIQGTVGAV 81 Query: 155 NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKA 214 + + P ++ +E++H+++YS + T E + F + KA Sbjct: 82 SLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTA-EIDDAFRWSEENRNLQRKA 140 Query: 215 EWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEG 274 E L+ + + L +R VA +E F F + R + LI RDE Sbjct: 141 EIVLQSYRGDEPL--KRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEA 198 Query: 275 LHTDFACLLFAH-------LKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLM 327 +H + F + +++ E + E Y D +G+ D+ Sbjct: 199 VHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVEYTQDLY--DEVGLTEDV- 255 Query: 328 NQYVEFVADRLLVAFGNKKYYK 349 +++ + A++ L+ G + + Sbjct: 256 KKFLRYNANKALMNLGYEALFP 277 >4N83-A nrPDB Length = 319 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 53/302 (17%), Positives = 117/302 (38%), Gaps = 15/302 (4%) Query: 99 AYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFST 158 +++ FW I LS D+ DW +++ E+ + +V D + +E+ V+ Sbjct: 21 TWEKLTEQFWLDTRIPLSNDLDDWR-KLSHKEKDLVGKVFGGLTLLDTLQSESGVDALRK 79 Query: 159 EVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWAL 218 +V+ ++ + +E++H+++YS + T E + +F +T P + +KAE Sbjct: 80 DVRTAHEEAVFNNIQFMESVHAKSYSSIFSTL-NTKSEIDEIFAWTNTNPYLQKKAEIIN 138 Query: 219 RWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTD 278 + AL E+ +A +E F F + + + + +LI RDE +H Sbjct: 139 EIYLNGTAL--EKKIASVFLETFLFYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGT 196 Query: 279 FACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALP-----VALLGMNADLMNQYVEF 333 + F N+ EK+ ++ + + +G ++ ++ + Sbjct: 197 YIGYKFQLAFNELPEDEQEKLKEWMYDLLYTLYENEEGYTESLYDTVGWTEEV-KTFLRY 255 Query: 334 VADRLLVAFGNKKYYK----VENPFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQE 389 A++ L+ G + NP + +FF + + Y G + + Sbjct: 256 NANKALMNLGQDPLFPDSADDVNPIVMNGISTGTSNHDFFSQVGNGYL-LGEVEAMQDDD 314 Query: 390 AG 391 Sbjct: 315 YN 316 >3MJO-A nrPDB Length = 296 Score = 237 bits (604), Expect = 8e-63, Method: Composition-based stats. Identities = 51/259 (19%), Positives = 100/259 (38%), Gaps = 10/259 (3%) Query: 98 QAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFS 157 + + R +FW E+I +S DI WN +M E+ RV D I + Sbjct: 30 EVWDRLTGNFWLPEKIPVSNDIQSWN-KMTPQEQLATMRVFTGLTLLDTIQGTVGAISLL 88 Query: 158 TEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWA 217 + + ++ Y +E++H+++YS + T P+ +E F + KA+ Sbjct: 89 PDAETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQINEA-FRWSEENENLQRKAKII 147 Query: 218 LRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHT 277 + + D L ++ VA +E F F +L R + LI RDE +H Sbjct: 148 MSYYNGDDPL--KKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDESVHG 205 Query: 278 DFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVAL-----LGMNADLMNQYVE 332 + + K A E+ ++ + + + LG D+ +++ Sbjct: 206 YYIGYKYQQGVKKLSEAEQEEYKAYTFDLMYDLYENEIEYTEDIYDDLGWTEDV-KRFLR 264 Query: 333 FVADRLLVAFGNKKYYKVE 351 + A++ L G + + + Sbjct: 265 YNANKALNNLGYEGLFPTD 283 >6GP2-A nrPDB Length = 345 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 62/309 (20%), Positives = 117/309 (37%), Gaps = 23/309 (7%) Query: 98 QAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIV-NENLVENF 156 + + R +FW E+I +S D+ W + + I+R D I V Sbjct: 47 EVWNRITQNFWLPEKIPVSNDLTSWRT-LTPEWQELITRTFTGLTLLDTIQATVGDVAQV 105 Query: 157 STEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEW 216 + E + F + +H+ ++ + T + E + + E+A+ Sbjct: 106 PNSLTDHEQVIYTNF-AFMVAVHARSFGSIFSTLCSSEQIEEAH-EWVINTETLQERAKA 163 Query: 217 ALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLH 276 + + + D L + VA A + G G F F+L RG +P + LI RD+ +H Sbjct: 164 LIPYYVNDDPL--KSKVAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIH 221 Query: 277 TDFACLLFAHLKNKPDP-------AIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQ 329 ++ + K P V K++ E +++E+ Y + G+ AD + Sbjct: 222 NYYSGYKYQKKVAKLSPEKQAEMKEFVFKLLYELIDLEKAYLKELYED--FGL-ADDAIR 278 Query: 330 YVEFVADRLLVAFGNKKYYKVE----NPFDFMENISLA-GKTNFFEKRVSDYQKAGVMSK 384 + + A + L G + E P F + + A +FF S Y +S+ Sbjct: 279 FSVYNAGKFLQNLGYDSPFTEEETRIEPEIFTQLSARADENHDFFSGNGSSY--IMGVSE 336 Query: 385 STKQEAGAF 393 T+ + F Sbjct: 337 ETEDDDWEF 345 >1PIY-A nrPDB Length = 375 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 79/374 (21%), Positives = 146/374 (39%), Gaps = 49/374 (13%) Query: 67 HKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQ-AYKRAEASFWTAEEIDLSKDIHDWNNR 125 + K + +EP+ + + ++I++ ++ + FW EE+D+S+D D+ Sbjct: 6 SQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQAL 65 Query: 126 MNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSL 185 + FIS L + D I + + IPE +++ E IHS +Y+ Sbjct: 66 PEHEKHIFISN-LKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTH 124 Query: 186 LIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADA------LFGER-------- 231 +I + DP +F+ I T +I ++AE + + L GE Sbjct: 125 IIRNIVNDPS---VVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKT 181 Query: 232 ---------------LVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLH 276 L++ ++E + F SFA F +R +M G LI RDE LH Sbjct: 182 VTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALH 241 Query: 277 TDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPV------------ALLGMNA 324 + L++ D + +I E + F+ A +++G+N Sbjct: 242 LTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNK 301 Query: 325 DLMNQYVEFVADRLLVAFGNKKYYKVE-NPFDFMEN--ISLAGKTNFFEKRVSDYQKAGV 381 D++ QYVE++ + + A G + NP ++ +S + E VS Y + Sbjct: 302 DILCQYVEYITNIRMQAVGLDLPFNTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQI 361 Query: 382 MSKSTKQEAGAFTF 395 S+ + F Sbjct: 362 DSEVDTDDLSNFQL 375 >6EBP-A nrPDB Length = 355 Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats. Identities = 54/304 (17%), Positives = 110/304 (36%), Gaps = 21/304 (6%) Query: 98 QAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNE-NLVENF 156 + + R +FW E I +S D+ WN ++++ + I+R D + + V Sbjct: 57 EVWNRVTQNFWLPENIPVSNDLPSWN-ELDDDWQQLITRTFTGLTLLDTVQSSIGDVAQI 115 Query: 157 STEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEW 216 + E + F + +H+ ++ + T + E + + + + Sbjct: 116 KNSLTEQEQVIYANF-AFMVGVHARSFGTIFSTLCTSEQIEEAH-EWVVDNEALQARPKA 173 Query: 217 ALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLH 276 + + D L + +A A + G G F F+L RG +P + LI RD+ +H Sbjct: 174 LIPFYTADDPL--KSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIH 231 Query: 277 TDFACLLFAHLKNKPDPA-------IVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQ 329 ++ + K P V ++ + + +E+ Y G+ AD + Sbjct: 232 NFYSGYKYQLKVAKLSPEKQAEMKQFVFDLLDKMIGLEKTYLHQLY--DGFGL-ADEAIR 288 Query: 330 YVEFVADRLLVAFGNKKYYKVEN----PFDFMENISLA-GKTNFFEKRVSDYQKAGVMSK 384 + + A + L G + + E P F + + A +FF S Y Sbjct: 289 FSLYNAGKFLQNLGYESPFTKEETRIAPEVFAQLSARADENHDFFSGSGSSYIIGTSEET 348 Query: 385 STKQ 388 + Sbjct: 349 LDED 352 >6QRZ-A nrPDB Length = 328 Score = 144 bits (364), Expect = 5e-35, Method: Composition-based stats. Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 30/229 (13%) Query: 89 FPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASD--- 145 FP+K ++I + FW +ID SKD DW +++++E+ ++ +++ F A + Sbjct: 44 FPMKLYQI------GKRLFWDPAKIDFSKDKEDW-KKLSKDEKNYLLNIVSLFMAGEEAV 96 Query: 146 ---------GIVNENLVEN--FSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDP 194 ++NE VE+ + + EAK F+ +++ L I T +P Sbjct: 97 AVDITPLISTMINEGRVEDVIYLEQFAFEEAKHAEAFRRFCDSLEIND-DLTIFTTEYNP 155 Query: 195 KESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASI-FWL 253 + + + ++ W LR + L +EGV + + Sbjct: 156 WYQKIFYEELPSV-------MWKLRVDPSPENLAVAVTTYNLYVEGVAAESGYKTFKHIF 208 Query: 254 KKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTE 302 +MPGL+ + LI DE H + L L + +I K + + Sbjct: 209 NSLNIMPGLSKTVNLIATDESRHIAYGTYLITRLIVENGESIYRKAIEQ 257 >6CWO-A nrPDB Length = 344 Score = 92.1 bits (227), Expect = 4e-19, Method: Composition-based stats. Identities = 52/314 (16%), Positives = 111/314 (35%), Gaps = 25/314 (7%) Query: 84 ERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAA 143 +R P +Y E+ Q + ++W E+D + D D++ ++ E+ + L A Sbjct: 26 KRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQ 85 Query: 144 SDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNA 203 + V ++ N PE E HSE YS L++ + + F Sbjct: 86 IEVAV-KSFWGNIYEHFPKPEFNGLGSTFAECEFRHSEAYSRLLEVLGYNDE-----FEK 139 Query: 204 IHTIPEIGEKAEWALRWIQDADA-----LFGERLVAFASIEGVFFSGSFASIFWLKK-RG 257 + +P I + ++ ++D + ++ IE V FA + + +G Sbjct: 140 LLDVPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFKG 199 Query: 258 MMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAI-------VEKIVTEAVEIEQRY 310 M ++ DE +H + + ++ + V + V +++ +E Sbjct: 200 YMKNVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDI 259 Query: 311 FLDALPVALL-GMNADLMNQYVEFVADRLLVAFGNKKYYKVE----NPFDFM-ENISLAG 364 + + + +++F D L + V+ + E + Sbjct: 260 LDWIFEEGEIESIKKGDLVNFMKFRIDESLKQINIPVIFDVKVEDYKALAWFEEEVFANS 319 Query: 365 KTNFFEKRVSDYQK 378 +FF KR +Y K Sbjct: 320 LDDFFAKRPVEYTK 333 >5OLK-A nrPDB Length = 430 Score = 88.3 bits (217), Expect = 5e-18, Method: Composition-based stats. Identities = 60/316 (18%), Positives = 128/316 (40%), Gaps = 25/316 (7%) Query: 84 ERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAA 143 +R L P +Y E+ + S+W E + + DI D+ ++E ER I + + Sbjct: 112 KRINLKPYEYPELNEYVAAIRHSYWIHTEFNFTSDIQDFKTGLSEVERSAIKNTMLAISQ 171 Query: 144 SDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNA 203 + V + + + PE + E H + YS L++ + + F Sbjct: 172 IEVAV-KTFWGDVHHRLPKPEIAAVGATFAESEVRHHDAYSHLLEILGLNEE-----FKE 225 Query: 204 IHTIPEIGEKAEWALRWI----QDADALFGERLVAFA-SIEGVFFSGSFASIFWLKK-RG 257 + P I ++ + + D D + E ++ FA IE V F I K + Sbjct: 226 LKKKPVIMKRVHYLETSLKHAKSDDDREYTESILLFALFIEHVSLFSQFLIIMAFNKHKN 285 Query: 258 MMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDP-------AIVEKIVTEAVEIEQRY 310 M+ G++ + E ++E +H DF + +K + +++++ + E E + Sbjct: 286 MLKGISNAVEATSKEEQIHGDFGVDIINIIKKENPEWFDEEHNNLIKEMCLNSFEAESKV 345 Query: 311 FLDALPVALLG-MNADLMNQYVEFVADRLLVAFGNKKYYKVENPF----DFMENISLAGK 365 L + ++N++++ ++ L A G +K + ++ ++ ++ + K Sbjct: 346 VDWIFEKGELDFLPKAVINEFLKNRFNKSLEAIGLEKLFDIDEALLQETEWFDDEIIGTK 405 Query: 366 T-NFFEKRVSDYQKAG 380 +FF KR +Y K Sbjct: 406 HGDFFVKRSINYSKRT 421 >6CWP-A nrPDB Length = 307 Score = 86.0 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 45/282 (15%), Positives = 100/282 (35%), Gaps = 20/282 (7%) Query: 84 ERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAA 143 +R P +Y E+ Q + ++W E+D + D D++ ++ E+ + L A Sbjct: 13 KRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQ 72 Query: 144 SDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNA 203 + V ++ N PE E HSE YS L++ + + F Sbjct: 73 IEVAV-KSFWGNIYEHFPKPEFNGLGSTFAECEFRHSEAYSRLLEVLGYNDE-----FEK 126 Query: 204 IHTIPEIGEKAEWALRWIQDADA-----LFGERLVAFASIEGVFFSGSFASIFWLKK-RG 257 + +P I + ++ ++D + ++ IE V FA + + +G Sbjct: 127 LLDVPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIENVSLFSQFAILLSFTRFKG 186 Query: 258 MMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAI-------VEKIVTEAVEIEQRY 310 M ++ DE +H + + ++ + V + V +++ +E Sbjct: 187 YMKNVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDI 246 Query: 311 FLDALPVALL-GMNADLMNQYVEFVADRLLVAFGNKKYYKVE 351 + + + +++F D L + V+ Sbjct: 247 LDWIFEEGEIESIKKGDLVNFMKFRIDESLKQINIPVIFDVK 288 >4AC8-A nrPDB Length = 323 Score = 83.6 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 42/268 (15%), Positives = 95/268 (35%), Gaps = 36/268 (13%) Query: 98 QAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENL---VE 154 + + A FW +ID ++D DW +++++ER + +R+ F A + V E++ + Sbjct: 31 KLFAGGNAKFWHPADIDFTRDRADWE-KLSDDERDYATRLCTQFIAGEEAVTEDIQPFMS 89 Query: 155 NFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKD----------PKESEFLFNAI 204 E ++ + F E H++ + + +D P + + + Sbjct: 90 AMRAEGRLADEMYLTQF-AFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAEL 148 Query: 205 HTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLK---KRGMMPG 261 AL A + +EG+ + + W K +R ++PG Sbjct: 149 PECLN-------ALSADPSPAAQVRASVTYNHIVEGMLALTGYYA--WHKICVERAILPG 199 Query: 262 LTFSNELICRDEGLHTDFACLLFAHLKNKPD------PAIVEKIVTEAVEIEQRYFLDAL 315 + I DE H + D + +++ A+ + + F Sbjct: 200 MQELVRRIGDDERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYG 259 Query: 316 PVALLGMNADLMNQYVEFVADRLLVAFG 343 ++ D ++++ D+ + FG Sbjct: 260 DQPPFDLSKD---DFLQYSTDKGMRRFG 284 >5OMK-A nrPDB Length = 316 Score = 75.6 bits (184), Expect = 4e-14, Method: Composition-based stats. Identities = 37/226 (16%), Positives = 80/226 (35%), Gaps = 23/226 (10%) Query: 94 HEIWQAYKRAEAS-FWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENL 152 H +++ Y++A+ + W +ID S+D D+ + + E+ ++A F+A + V ++ Sbjct: 32 HPMFKLYEKAKRNGKWNPADIDFSQDQKDFAS-LTSEEKISALPLVAGFSAGEEAVTLDI 90 Query: 153 VENFSTEVQIPEAKSFYGFQIMI--ENIHSETYS---------LLIDTYIKDPKESEFLF 201 + + + + E H E +S + + + + Sbjct: 91 LPMAHALARQGRLEDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFY 150 Query: 202 NAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFW-LKKRGMMP 260 A+ A L +A+ V +EG + + KK G+ P Sbjct: 151 EALPE-------AMNRLYADDSPEAVIRAATVYNMIVEGTLAESGYYTFRQIYKKAGLFP 203 Query: 261 GLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEI 306 GL + + DEG H F + N+ ++ ++ Sbjct: 204 GLLQGIDYLNMDEGRHIQFGIYTIQRIVNE--DERYYELFIRYMDE 247 >1ZA0-A nrPDB Length = 275 Score = 32.8 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 39/120 (32%), Gaps = 17/120 (14%) Query: 168 FYGFQIMIENIHSETY-SLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADA 226 + G E++H+ L+ T DP +E + + + ++ + Sbjct: 99 WLGRWTAEEHLHAIALREYLVVTREVDPVANEDV------------RVQHVMKGYRAEKY 146 Query: 227 LFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAH 286 E LV A E L + P L + I RDE H +F L H Sbjct: 147 TQVETLVYMAFYERC----GAVFCRNLAAQIEEPILAGLIDRIARDEVRHEEFFANLVTH 202 >3Q3N-A nrPDB Length = 500 Score = 32.4 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 28/163 (17%), Positives = 50/163 (30%), Gaps = 13/163 (7%) Query: 147 IVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHT 206 + E + FS P ++ F +M E H + Y K ++ ++ + A H+ Sbjct: 108 VTGEGRMARFSK---APGNRNMATFGMMDELRHGQLQLFFPHEYCKKDRQFDWAWRAYHS 164 Query: 207 IPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTF-- 264 A A + D + G ++ A + F F ++ +L Sbjct: 165 NEW----AAIAAKHFFDDI-ITGRDAISVAIMLTFSFETGFTNMQFLGLAADAAEAGDYT 219 Query: 265 ---SNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAV 304 I DE H L +K V A+ Sbjct: 220 FANLISSIQTDESRHAQQGGPALQLLIENGKREEAQKKVDMAI 262 >3N1X-A nrPDB Length = 498 Score = 32.0 bits (71), Expect = 0.44, Method: Composition-based stats. Identities = 28/170 (16%), Positives = 50/170 (29%), Gaps = 10/170 (5%) Query: 140 FFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEF 199 A + + + P ++ F +M EN H + +K ++ ++ Sbjct: 98 GAIALEEYAASTAEARMARFAKAPGNRNMATFGMMDENRHGQIQLYFPYANVKRSRKWDW 157 Query: 200 LFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWL-----K 254 AIHT A A R D + VA + + F F ++ +L Sbjct: 158 AHKAIHTNEW----AAIAARSFF-DDMMMTRDSVAVSIMLTFAFETGFCNMQFLGLAADA 212 Query: 255 KRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAV 304 I DE H L +++V A+ Sbjct: 213 AEAGDHTFASLISSIQTDESRHAQQGGPSLKILVENGKKDEAQQMVDVAI 262 >3ETC-A nrPDB Length = 580 Score = 31.6 bits (70), Expect = 0.67, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 20/37 (54%) Query: 322 MNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFME 358 +N ++ N+++EF +L+ FG + F +ME Sbjct: 353 LNPEVFNRFLEFTGIKLMEGFGQTETVVTIATFPWME 389 >1ZVU-A nrPDB Length = 716 Score = 30.9 bits (68), Expect = 0.93, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 14 LSDLEIKDSKSNLNKE---LETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLK 70 L +++I+ +S L KE L+ + R +++LK++L DA+ + +S R + K Sbjct: 402 LEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAK 461 Query: 71 EMEKEEPLLNE 81 M + + L +E Sbjct: 462 AMSEHDMLPSE 472 >5FTW-A nrPDB Length = 256 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 40/246 (16%), Positives = 82/246 (33%), Gaps = 25/246 (10%) Query: 39 VKSDMLKEKLSKDAENHKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQ 98 V + KE K K Q + +EK++ LLNE +R + +++ ++ Sbjct: 17 VDLTLYKEAQMKRRLTSLYEKKGFQSFKDFAAALEKDQALLNETLDRMTINVSEFYRNYK 76 Query: 99 AYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFST 158 ++ E + I S+ + W+ + E + D + +T Sbjct: 77 RWEVLETAI-LPL-IKTSRPLKIWSAACSTGEEPY-----TLAMLLDQQKGLPGYQILAT 129 Query: 159 EVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWAL 218 ++ + ++ S+ + ++ S + I + A Sbjct: 130 DIDEKALEKAKKGVYQERSLQEVPLSVKDRYFTQNANRSYEVKTEIKKNITFKKHNLLAD 189 Query: 219 RWIQD-----------------ADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPG 261 R+ QD + L+ + + GV F GS IF +K G++P Sbjct: 190 RYEQDFDLIVCRNVFIYFTESAKEELYLK-MAHSLKKNGVLFVGSTEQIFNPEKFGLVPA 248 Query: 262 LTFSNE 267 TF + Sbjct: 249 DTFFYQ 254 >4LHD-A nrPDB Length = 983 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Query: 109 TAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGI-VNENLVENFSTEVQIPEAKS 167 E++ + D + E E+ + + L F D I F +Q+P ++S Sbjct: 23 LEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQAVPPAIRFPRSLQLPASQS 82 Query: 168 FYGFQIMIENIHSETYSLLIDTYI 191 YG +++I S+ + + +YI Sbjct: 83 EYGAIAQLKSIASK--NQVFRSYI 104 >4F7Z-A nrPDB Length = 999 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 53/159 (33%), Gaps = 10/159 (6%) Query: 217 ALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLH 276 L+W L E VA A +E + S S + + +P L + I D Sbjct: 569 VLQWAAMYGDLLQEDDVAMAFLEEFYVSVSDDARMMAAFKEQLPELEKIVKQISEDAKAP 628 Query: 277 TDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGM-NADLMNQYVEFVA 335 +L + A + + + E+ + + + + A + + + VA Sbjct: 629 QKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVA 688 Query: 336 DRL---------LVAFGNKKYYKVENPFDFMENISLAGK 365 D+L + G +K N +++ G+ Sbjct: 689 DKLGSGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGR 727 >3CHI-A nrPDB Length = 336 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 34/109 (31%) Query: 260 PGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVAL 319 P + L RDE H + L + + +V + + L L Sbjct: 214 PMHSLITTLHLRDETAHGSIVVEVVRELYARMNEQQRRALVRCLPIALEAFAEQDLSALL 273 Query: 320 LGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNF 368 L +NA + E V D A G + +E + L +F Sbjct: 274 LELNAAGIRGAEEIVGDLRSTAGGTRLVRDFSGARKMVEQLGLDDAVDF 322 >6MEL-B nrPDB Length = 387 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 40/97 (41%), Gaps = 4/97 (4%) Query: 188 DTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERL---VAFASIEGVFFS 244 D+ + E L + P E AE+ L +++ + +A A+++ + +S Sbjct: 220 DSALYRHPEIAELRDTTEENPAEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYS 279 Query: 245 GSFASIFWLKKRGMMPGL-TFSNELICRDEGLHTDFA 280 G+ + F G P + E+I RD+ + F Sbjct: 280 GAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFI 316 >4MGY-E nrPDB Length = 694 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 53/159 (33%), Gaps = 10/159 (6%) Query: 217 ALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLH 276 L+W L E VA A +E + S S + + +P L + I D Sbjct: 264 VLQWAAMYGDLLQEDDVAMAFLEEFYVSVSDDARMMAAFKEQLPELEKIVKQISEDAKAP 323 Query: 277 TDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGM-NADLMNQYVEFVA 335 +L + A + + + E+ + + + + A + + + VA Sbjct: 324 QKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVA 383 Query: 336 DRL---------LVAFGNKKYYKVENPFDFMENISLAGK 365 D+L + G +K N +++ G+ Sbjct: 384 DKLGSGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGR 422 >1ZVD-A nrPDB Length = 380 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 22/142 (15%), Positives = 43/142 (30%), Gaps = 12/142 (8%) Query: 228 FGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHL 287 F R++ A G + G F F+ + G L EL+ D LH +L + Sbjct: 117 FVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDM-ELV--DPDLHNSLVWILENDI 173 Query: 288 KNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVA------ 341 D + I+ + + +N + +YV + + Sbjct: 174 TGVLDHTFCVEHNAYGEIIQHELKPNG---KSIPVNEENKKEYVRLYVNWRFLRGIEAQF 230 Query: 342 FGNKKYYKVENPFDFMENISLA 363 +K + P ++ Sbjct: 231 LALQKGFNEVIPQHLLKTFDEK 252 >1SB7-A nrPDB Length = 368 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 16/47 (34%), Gaps = 4/47 (8%) Query: 69 LKEMEKEEPLLNED----KERTVLFPIKYHEIWQAYKRAEASFWTAE 111 E E + L+ E + +L+P + W E FW Sbjct: 299 AAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPA 345 >5EUT-A nrPDB Length = 556 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 20/34 (58%), Gaps = 3/34 (8%) Query: 89 FPIKYHEIWQAYKRAEASFWTAE-EIDLSKDIHD 121 FP+K+ + W+AY A W + ++ S++I D Sbjct: 439 FPLKHPDSWRAYPFYWA--WLPQAKVPFSQEIKD 470 >2X5F-A nrPDB Length = 430 Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 41/121 (33%), Gaps = 5/121 (4%) Query: 129 NERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLID 188 NE+ S AF SD N + ++ ++ ++ M N + ++ +D Sbjct: 11 NEQLQQSNATAFAMLSDLGQNMFYPKGILSQSAEAKSTTYNATIGMATNKDGKMFASSLD 70 Query: 189 TYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERL----VAFASIEGVFFS 244 D E +F + W + ++D L + + V A G+ Sbjct: 71 AMFNDLTPDE-IFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSRPIVTNALTHGLSLV 129 Query: 245 G 245 G Sbjct: 130 G 130 >5K52-A nrPDB Length = 265 Score = 28.6 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 32/221 (14%), Positives = 60/221 (27%), Gaps = 20/221 (9%) Query: 127 NENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLL 186 +E + SR+ A + N V E+ +PE +E H + ++ Sbjct: 46 SETYKDAYSRINAIVIEGEDEAANNYVR--LAEL-MPEQSEELASLAKMEARHKKGFTAC 102 Query: 187 IDTYIKDPKES--EFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFS 244 P + F+ +H ++ A + + L+ IE S Sbjct: 103 GKNLNVTPDMDFAKKFFSDLHGNFQVAAAAGNIVTCL----------LIQALIIEAFAIS 152 Query: 245 GSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAV 304 I E + +DE LH +F + Sbjct: 153 AYNVYIPHADDFAR-----KITENVVKDEYLHLNFGEQWLKANFESAKDELERANRENLA 207 Query: 305 EIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNK 345 + + A +LGM + + + L G Sbjct: 208 IVWRMLDEVAGDALVLGMEKEALMEDFTIAYQEALQNIGFS 248 >4HNE-A nrPDB Length = 384 Score = 28.6 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 20/34 (58%), Gaps = 3/34 (8%) Query: 89 FPIKYHEIWQAYKRAEASFWTAE-EIDLSKDIHD 121 FP+K+ + W+AY A W + ++ S++I D Sbjct: 282 FPLKHPDSWRAYPFYWA--WLPQAKVPFSQEIKD 313 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.128 0.320 Lambda K H 0.267 0.0394 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,737,823 Number of Sequences: 36641 Number of extensions: 520901 Number of successful extensions: 1927 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 47 Number of HSP's that attempted gapping in prelim test: 1724 Number of HSP's gapped (non-prelim): 124 length of query: 399 length of database: 10,336,785 effective HSP length: 99 effective length of query: 300 effective length of database: 6,709,326 effective search space: 2012797800 effective search space used: 2012797800 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)