BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09917 (674 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3O8Y-A nrPDB 1368 0.0 4NRE-A nrPDB 539 e-153 2FNQ-A nrPDB 521 e-148 2P0M-A nrPDB 489 e-138 3RDE-A nrPDB 455 e-128 3VF1-A nrPDB 449 e-126 3D3L-A nrPDB 409 e-114 5MEF-A nrPDB 244 7e-65 4G32-A nrPDB 204 1e-52 1RRL-A nrPDB 189 3e-48 2IUJ-A nrPDB 186 4e-47 2IUK-A nrPDB 171 7e-43 4WFO-A nrPDB 158 6e-39 6NS2-A nrPDB 113 3e-25 5FNO-A nrPDB 100 3e-21 5FX8-A nrPDB 92 9e-19 5EK8-A nrPDB 45 1e-04 1KHO-A nrPDB 44 2e-04 2WXU-A nrPDB 43 4e-04 1OLP-A nrPDB 35 0.11 1PHP-A nrPDB 35 0.15 1VPE-A nrPDB 33 0.41 5ZCR-A nrPDB 30 2.6 4V8D-BP nrPDB 29 7.3 >3O8Y-A nrPDB Length = 691 Score = 1368 bits (3541), Expect = 0.0, Method: Compositional matrix adjust. Identities = 660/674 (97%), Positives = 661/674 (98%), Gaps = 3/674 (0%) Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60 MPSYTVTVATGSQ AGTDDYIYLSLVGSAGCSEKHLLDK FERGAVDSYDVTVDE Sbjct: 21 MPSYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDK---GSFERGAVDSYDVTVDE 77 Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA 120 ELGEIQLVRIEKRKY NDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA Sbjct: 78 ELGEIQLVRIEKRKYGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA 137 Query: 121 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL 180 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL Sbjct: 138 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL 197 Query: 181 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG 240 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG Sbjct: 198 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG 257 Query: 241 CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP 300 NPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP Sbjct: 258 ANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP 317 Query: 301 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF 360 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF Sbjct: 318 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF 377 Query: 361 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG 420 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG Sbjct: 378 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG 437 Query: 421 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE 480 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE Sbjct: 438 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE 497 Query: 481 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL 540 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL Sbjct: 498 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL 557 Query: 541 TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW 600 TVVIFTASAQHAAVNFGQYDW SWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW Sbjct: 558 TVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW 617 Query: 601 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY 660 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERN+ QLPY Sbjct: 618 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNENLQLPY 677 Query: 661 YYLSPDRIPNSVAI 674 YYLSPDRIPNSVAI Sbjct: 678 YYLSPDRIPNSVAI 691 >4NRE-A nrPDB Length = 696 Score = 539 bits (1389), Expect = e-153, Method: Compositional matrix adjust. Identities = 288/682 (42%), Positives = 426/682 (62%), Gaps = 14/682 (2%) Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60 M + V V+TG + AGT D + +S+VG+ G S LD +F GA + + VT+ E Sbjct: 21 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPE 79 Query: 61 ELGEIQLVRIEKRKYWLN-------DDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113 ++G + L+R+ K L D W+ ++ L P G ++ FPCY+W+ G +VL+ Sbjct: 80 DVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQ 139 Query: 114 DGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSE 173 +G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ + Sbjct: 140 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 199 Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233 K +F L A + I + + W + ++IF +E HWQED F Sbjct: 200 KNANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFF 258 Query: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293 QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI Sbjct: 259 ASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI 318 Query: 294 DANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAK 352 N + QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK Sbjct: 319 QTNVIN-GKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAK 377 Query: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412 WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FKLL+ H R+T+ INT AR Sbjct: 378 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLAR 437 Query: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472 E LI + D++ G G +++QR MK L Y+ LC PE I+ RG+E DIP Y+YR Sbjct: 438 ELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVE---DIPGYYYR 494 Query: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532 DDG+ +W A+ F +E++ IYY D+ V++D ELQ +V +++ G ++SSG P S+++ Sbjct: 495 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 554 Query: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592 RE L +Y+T+VIFT SA+HAAV+ GQ+D C+W+PN PP+M+ PPPT+KG+ T E + TL Sbjct: 555 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 614 Query: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652 P +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ER Sbjct: 615 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 674 Query: 653 NKKKQLPYYYLSPDRIPNSVAI 674 N+ LPY YL P I NSV+I Sbjct: 675 NQGLVLPYTYLDPPLIENSVSI 696 >2FNQ-A nrPDB Length = 699 Score = 521 bits (1343), Expect = e-148, Method: Compositional matrix adjust. Identities = 273/695 (39%), Positives = 413/695 (59%), Gaps = 28/695 (4%) Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63 Y V V TG + AGTD I + + G+ G ++ LDK F+NDFE G+ + Y V ++G Sbjct: 9 YNVEVETGDREHAGTDATITIRITGAKGRTDYLKLDKWFHNDFEAGSKEQYTVQ-GFDVG 67 Query: 64 EIQLVRI--EKRKYWLND-DWYLKYITLKTPHGDYI-EFPCYRWITGDVEVVLRDGRAKL 119 +IQL+ + + YW D DW++ + + + D + FPC+RW+ D+ VL G A L Sbjct: 68 DIQLIELHSDGGGYWSGDPDWFVNRVIIISSTQDRVYSFPCFRWVIKDM--VLFPGEATL 125 Query: 120 ARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFV 179 ++ I+ + R+KELE R+ Y+W + P +I AK H DLPRD+QF EK + Sbjct: 126 PFNEVPAIVSEQRQKELEQRKLTYQWDYVSDDMPGNIKAKTHDDLPRDVQFTDEKSRSYQ 185 Query: 180 LNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLN 239 + A+ NL I MF++ W+ + D+ ++ + + + W ED FGYQFLN Sbjct: 186 ESRKAALVNLGIGSLFTMFEN-WDSYDDYHILYRNWILGGTPNMADRWHEDRWFGYQFLN 244 Query: 240 GCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI------ 293 G NPV++ RC LP PVT E V SL+R +L++E++ G+I+IVDF++L G Sbjct: 245 GANPVILTRCDALPSNFPVTNEHVNASLDRGKNLDEEIKDGHIYIVDFKVLVGAKSYGGP 304 Query: 294 ----------DANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLP-S 342 D K D +++ AAP+ L Y N ++PIAIQ+NQ PG ENPI+ P Sbjct: 305 VLEDIGYKVPDHLKHDEADIRYCAAPLALFYVNKLGHLMPIAIQINQEPGPENPIWTPHE 364 Query: 343 DAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVR 402 + ++DW++AK W+ ++ + HQ THLLRTHL +E F ++ +R L + HP+FKLL H+ Sbjct: 365 ENEHDWMMAKFWLGVAESNFHQLNTHLLRTHLTTESFALSTWRNLASAHPVFKLLQPHIY 424 Query: 403 FTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMES 462 +AI+T R++LI G+ D++ + GGGGHV +++ K++ P A+K RG++ Sbjct: 425 GVLAIDTIGRKELIGSGGIVDQSLSLGGGGHVTFMEKCFKEVNLQDYHLPNALKKRGVDD 484 Query: 463 KEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMR--- 519 +P ++YRDDGL +WEAI TF E++ I+Y+ D V+ D E+Q ++ DV+ G R Sbjct: 485 PSKLPGFYYRDDGLALWEAIETFIGEIIAIFYKNDDDVKRDNEIQSWIYDVHKNGWRVNP 544 Query: 520 GRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTA 579 G + G P S +SREQL E LT ++FT S QHAAVNF Q D + PNAP +R PPP Sbjct: 545 GHQDHGVPASFESREQLKEVLTSLVFTFSCQHAAVNFSQKDHYGFTPNAPAVLRHPPPKK 604 Query: 580 KGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFR 639 KG T++ I+ TLP + ++ + V+ L++F E+E +LG Y + +K +A+ RF+ Sbjct: 605 KGEATLQSILSTLPSKSQAAKAIATVYILTKFSEDERYLGNYSATAWEDKDALDAINRFQ 664 Query: 640 KNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674 LE I I +RN+ ++PY YL P+RIPN AI Sbjct: 665 DKLEDISKKIKQRNENLEVPYIYLLPERIPNGTAI 699 >2P0M-A nrPDB Length = 662 Score = 489 bits (1259), Expect = e-138, Method: Compositional matrix adjust. Identities = 261/675 (38%), Positives = 391/675 (57%), Gaps = 19/675 (2%) Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63 Y V V+TG+ +AG+ + + L LVG G E +P N E + V V + LG Sbjct: 3 YRVCVSTGASIYAGSKNKVELWLVGQHGEVELGSCLRPTRNKEEE-----FKVNVSKYLG 57 Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPHG--DYIEFPCYRWITGDVEVVLRDGRAKLAR 121 + VR+ K+ + D W+ +I+++ D FPCYRW+ GD L G Sbjct: 58 SLLFVRLRKKHFLKEDAWFCNWISVQALGAAEDKYWFPCYRWVVGDGVQSLPVGTGCTTV 117 Query: 122 DDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLN 181 D + ++HR +ELE R+K Y+W W G L++ DLP D +F +K +DF + Sbjct: 118 GDPQGLFQKHREQELEERRKLYQWGSWKEGLILNVAGSKLTDLPVDERFLEDKKIDFEAS 177 Query: 182 YSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGC 241 + + L + +++ + W DF +IF + ++ RV + WQED +FGYQFLNG Sbjct: 178 LAWGLAELALKNSLNIL-APWKTLDDFNRIFWCGRSKLARRVRDSWQEDSLFGYQFLNGA 236 Query: 242 NPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPC 301 NP+L+RR +LP +L M E Q LE+E++ G +F DF LLD I AN C Sbjct: 237 NPMLLRRSVQLPARLVFPPGMEEL----QAQLEKELKAGTLFEADFALLDNIKANVILYC 292 Query: 302 TLQFLAAPICLLYKNLANKIVPIAIQLN--QIPGDENPIFLPSDAKYDWLLAKIWVRSSD 359 Q+LAAP+ +L K++P+ IQL+ +I P+FLP+D WLLAK WVRSSD Sbjct: 293 Q-QYLAAPLVMLKLQPDGKLMPMVIQLHLPKIGSSPPPLFLPTDPPMVWLLAKCWVRSSD 351 Query: 360 FHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEC 419 F VH+ +HLLR HL++EVF +A R LP++HP+FKL+V H+R+T+ IN +AR L+ + Sbjct: 352 FQVHELNSHLLRGHLMAEVFTVATMRCLPSIHPVFKLIVPHLRYTLEINVRARNGLVSDF 411 Query: 420 GLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVW 479 G+FD+ +TGGGGHVQ++Q+A LTY S C P+ + RG+ E FY D L +W Sbjct: 412 GIFDQIMSTGGGGHVQLLQQAGAFLTYRSFCPPDDLADRGLLGVES---SFYAQDALRLW 468 Query: 480 EAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEY 539 E I + ++ +YY+ D+ V +D ELQ + ++ G++G + GFP S++S Q + Sbjct: 469 EIISRYVQGIMGLYYKTDEAVRDDLELQSWCREITEIGLQGAQKQGFPTSLQSVAQACHF 528 Query: 540 LTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSC 599 +T+ IFT + QH++++ GQ DW +W+PNAP TMR PPPT K T+E ++ TLP+ +S Sbjct: 529 VTMCIFTCTGQHSSIHLGQLDWFTWVPNAPCTMRLPPPTTKD-ATLETVMATLPNLHQSS 587 Query: 600 WHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLP 659 + VW L + Q + LG + EE+F + + +FR+ L + I RN+K +P Sbjct: 588 LQMSIVWQLGRDQPIMVPLGQHQEEYFSGPEPRAVLEKFREELAIMDKEIEVRNEKLDIP 647 Query: 660 YYYLSPDRIPNSVAI 674 Y YL P + NSVAI Sbjct: 648 YEYLRPSIVENSVAI 662 >3RDE-A nrPDB Length = 573 Score = 455 bits (1170), Expect = e-128, Method: Compositional matrix adjust. Identities = 235/563 (41%), Positives = 343/563 (60%), Gaps = 14/563 (2%) Query: 115 GRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEK 174 G A+ DD + K+HR +EL R+K YRW W G L+I + DLP D +F +K Sbjct: 22 GTARTVVDDPQGLFKKHREEELAERRKLYRWGNWKDGLILNIASTGIHDLPVDERFLEDK 81 Query: 175 GVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFG 234 +DF + +K + +L + +++ S WN F +IF + ++ERV + W+ED +FG Sbjct: 82 RIDFEASLAKGLADLAVKDSLNVLMS-WNSLDSFNRIFWSGQSKLAERVRDSWKEDALFG 140 Query: 235 YQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGID 294 YQFLNG NP+L+R ELP +L M E Q LE+E+Q G +F DF LLDGI Sbjct: 141 YQFLNGTNPMLLRHSVELPARLKFPPGMEEL----QAQLEKELQGGTLFEADFSLLDGIK 196 Query: 295 ANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPI---FLPSDAKYDWLLA 351 AN + Q+LA P+ +L K++P+ IQL Q+P + +P+ FLP+D WLLA Sbjct: 197 ANVI-LSSQQYLAVPLVMLKLQPDGKLLPMVIQL-QLPREGSPLPPLFLPTDPPMVWLLA 254 Query: 352 KIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKA 411 K WVRSSDF +H+ +HLLR HL++EV +A R LP++HPIFKLL+ H R+T+ IN +A Sbjct: 255 KCWVRSSDFQLHELHSHLLRGHLMAEVIAVATMRCLPSIHPIFKLLIPHFRYTMEINVRA 314 Query: 412 REQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFY 471 R L+ + G+FD+ +TGGGGHV++++RA LTY+S C P+ + RG+ E FY Sbjct: 315 RNGLVSDLGIFDQVVSTGGGGHVELLRRAAALLTYSSFCPPDDLADRGLLGVES---SFY 371 Query: 472 RDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVK 531 D L +WE I + +V ++Y+ D+ V+ED ELQ + + G+ G + GFP S++ Sbjct: 372 AQDALRLWEVISRYVEGIVSLHYKTDESVKEDFELQAWCREFTEIGLLGAQDRGFPVSLQ 431 Query: 532 SREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDT 591 S+EQL ++T+ IFT + QH++ + GQ DW +W+PNAP TMR PPPT K T+E ++ T Sbjct: 432 SKEQLCHFVTMCIFTCTGQHSSNHLGQLDWYTWVPNAPCTMRLPPPTTKD-ATLETVMAT 490 Query: 592 LPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAE 651 LP+ ++ + W L + Q + LG + EE+F K + +FR+ L A+ I Sbjct: 491 LPNFHQASLQMSITWQLGRCQPTMVALGQHEEEYFSGPGPKAVLTKFREELAALDKDIEV 550 Query: 652 RNKKKQLPYYYLSPDRIPNSVAI 674 RN K LPY YL P R+ NSVAI Sbjct: 551 RNAKLALPYEYLRPSRVENSVAI 573 >3VF1-A nrPDB Length = 698 Score = 449 bits (1155), Expect = e-126, Method: Compositional matrix adjust. Identities = 253/689 (36%), Positives = 388/689 (56%), Gaps = 30/689 (4%) Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHL-LDKPFYNDFERGAVDSYDVTVDEEL 62 Y +TV TG AGTD + + L G G LDK F+NDFE G D+YD + ++ Sbjct: 22 YKITVETGDLRGAGTDASVSIKLTGKDGAETSAFSLDKYFHNDFESGGTDTYDQS-GVDV 80 Query: 63 GEIQLVRIEKRKYWLNDDWYLKYITLK-----TPHGDYIEFPCYRWITGDVEVVLRDGRA 117 GEI ++ +++ + L DWY+ + ++ T + FPCYRW+ ++V+ +G+A Sbjct: 81 GEIAMITLKENGFGLKSDWYIAKVIIEKIDEATGFSNKYIFPCYRWVIK--QLVVYEGKA 138 Query: 118 KLARD-DQIHILKQHRRKELETRQKQYRW------MEWNPGFPLSIDAKCHKDLPRDIQF 170 L D + + + R KE+ +K Y+W ++ PGF +DA+ K LP+D+QF Sbjct: 139 ILPNSKDNVKTIAEQRTKEVSENKKLYKWGTDPRYVQDLPGF---VDAEEPKSLPKDVQF 195 Query: 171 DSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQED 230 E NL ++ ++ W+ DF ++ + +W++D Sbjct: 196 TDEATSSLFRVGLADFANLGLSHLFGIW-DDWDCLEDFRQLITPAIKSGLPHAAEYWRDD 254 Query: 231 LMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELL 290 + FG QFLNG NP +IRRC +LPE PV EMVE L+R +LE+ +++G IFI D+++L Sbjct: 255 VWFGSQFLNGSNPEVIRRCDKLPENFPVKNEMVEKLLDRGYTLEKAMKEGLIFITDYKIL 314 Query: 291 DGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLP-SDAKYDWL 349 +GI T P +++ P+ L Y + I+PIAIQL Q PG+ N I+ P D ++DW+ Sbjct: 315 EGIPTMDT-PEDKRYITTPLGLFYLKNNDDIIPIAIQLYQQPGENNSIWTPLKDTEWDWI 373 Query: 350 LAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINT 409 +AK+W+R +D HQ ITHLLR HL+ E ++ +R LP+VHP++KLL H + +AINT Sbjct: 374 MAKLWLRCADTQYHQMITHLLRCHLMMEPTAVSSWRNLPSVHPVWKLLYPHTKGIMAINT 433 Query: 410 KAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYY 469 R LI G DK + GGGG V ++Q+ + +T+ S + ++ RG++ + + Sbjct: 434 LGRNDLIPTGGAADKVLSIGGGGQVTLMQKHYRSVTFDSYDLVKDLRQRGVDG---LRKF 490 Query: 470 FYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDV----YVYGMRGRKSSG 525 +Y+DD LL+W I F +++ IYY D V++D E+QD++ D+ Y G G Sbjct: 491 YYKDDALLLWNVIHQFVQDIIQIYYNDDDSVKKDNEIQDWIRDLHENGYPAGSDGTDKK- 549 Query: 526 FPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTI 585 PKS ++RE+L +LTVV+FT S QHAAVNF Q + PN+P MR PPPT KG Sbjct: 550 VPKSFENREELVHFLTVVVFTCSCQHAAVNFSQMATYGFHPNSPTLMRQPPPTEKGKSNH 609 Query: 586 EQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAI 645 + I+ +L ++ ++ + V AL+ E FLG Y + F + AMA+F+ NL I Sbjct: 610 KVIMASLANKHQAVTMVSVVNALTTIYPTEKFLGDYADNLFGDAAAHAAMAKFKSNLANI 669 Query: 646 VSVIAERNKKKQLPYYYLSPDRIPNSVAI 674 I ERN+ PY +L P +PNS+AI Sbjct: 670 TKQITERNQGMVSPYTWLIPGHVPNSIAI 698 >3D3L-A nrPDB Length = 541 Score = 409 bits (1051), Expect = e-114, Method: Compositional matrix adjust. Identities = 212/501 (42%), Positives = 305/501 (60%), Gaps = 11/501 (2%) Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233 + +DF + + R ++ SSWN DF++IF + ++E+V WQ+D +F Sbjct: 16 ENLDFEWTLKAGALEMALKR-VYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELF 74 Query: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293 YQFLNG NP+L+RR T LP +L + + M E + LE+E+Q G++F DF LLDGI Sbjct: 75 SYQFLNGANPMLLRRSTSLPSRLVLPSGMEELRAQ----LEKELQNGSLFEADFILLDGI 130 Query: 294 DANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENP--IFLPSDAKYDWLLA 351 AN Q+LAAP+ +L K+ P+ IQ+ +FLPSD WLLA Sbjct: 131 PANVIR-GEKQYLAAPLVMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLA 189 Query: 352 KIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKA 411 K WVR+SDF +H+ HLL THLV+EV +A R LP +HPIFK L+ H+R+T+ INT+A Sbjct: 190 KSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRA 249 Query: 412 REQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFY 471 R QLI + G+FDKA +TGGGGHVQ+++RA LTY SLC P+ + RG+ +P Y Sbjct: 250 RTQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLG---LPGALY 306 Query: 472 RDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVK 531 D L +WE I + +V ++Y+ D +V+ DPELQ + ++ G+ + GFP S + Sbjct: 307 AHDALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQ 366 Query: 532 SREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDT 591 S+ QL +LT+ +FT +AQHAA+N GQ DW +W+PNAP TMR PPPT K VT+ ++ + Sbjct: 367 SQSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGS 426 Query: 592 LPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAE 651 LPD ++C + W LS+ Q + + LG + E++F K + +FR +LE + I Sbjct: 427 LPDVRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITA 486 Query: 652 RNKKKQLPYYYLSPDRIPNSV 672 RN++ PY YL P I NSV Sbjct: 487 RNEQLDWPYEYLKPSCIENSV 507 >5MEF-A nrPDB Length = 569 Score = 244 bits (624), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 165/575 (28%), Positives = 286/575 (49%), Gaps = 49/575 (8%) Query: 129 KQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMEN 188 ++ R + + +++ Y++ E + K LP+ F + +++ K + + Sbjct: 15 QEQRNRAIAQQREAYQYSE-------TAGILLIKTLPQSEMF----SLKYLIERDKGLVS 63 Query: 189 LFINRFMHMFQSSWNDF---ADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVL 245 L N ++ ++ F DFE++F + + VMN ++ D +F Q + G NP++ Sbjct: 64 LIANTLASNIENIFDPFDKLEDFEEMFPLLPKPL---VMNTFRNDRVFARQRIAGPNPMV 120 Query: 246 IRRCTE-LPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDA-------NK 297 I R + LP+ PVT M + + + +L + + QG +FI +++ L + N Sbjct: 121 IERVVDKLPDNFPVTDAMFQKIMFTKKTLAEAIAQGKLFITNYKGLAELSPGRYEYQKNG 180 Query: 298 TDPCTLQFLAAPICLL------YKNLANKIVPIAIQLNQIPGD-ENPIFLPSDAKYDWLL 350 T + +AAP+ L + + + PIAIQ+NQ P NPI+ P D K+ W + Sbjct: 181 TLVQKTKTIAAPLVLYAWKPEGFGDYRGSLAPIAIQINQQPDPITNPIYTPRDGKH-WFI 239 Query: 351 AKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTK 410 AKI+ + +D + H+ I+HL RTHL+ E F +A +L HP+ LL H +FT+AIN Sbjct: 240 AKIFAQMADGNCHEAISHLARTHLILEPFVLATANELAPNHPLSVLLKPHFQFTLAINEL 299 Query: 411 AREQLICECGLFDKANATGGGGHVQMVQRAMKDL--TYASLCFPEAIKARGM-------E 461 AREQ I G D A + +++ A+K+ + P + RG+ Sbjct: 300 AREQFISAGGYADDLLAGTLEASIAVIKAAIKEYMDNFTEFALPRELARRGVGIGDVDQR 359 Query: 462 SKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGR 521 + +P Y YRDD +L+W AI + + + +YY+ + +D ELQ++V + G Sbjct: 360 GENFLPDYPYRDDAMLLWNAIEVYVRDYLSLYYQSPVQIRQDTELQNWVRR--LVSPEGG 417 Query: 522 KSSGFPKS--VKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTA 579 + +G + + + E L T VIF + QHAAVN+ QYD+ ++IPN P A PP Sbjct: 418 RVTGLVSNGELNTIEALVAIATQVIFVSGPQHAAVNYPQYDYMAFIPNMPLATYATPPNK 477 Query: 580 KGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFR 639 + ++ I++ LP + + L + L F N L YP+ F++ ++ + +F+ Sbjct: 478 ESNISEATILNILPPQKLAARQLELMRTLCVFYPNRL---GYPDTEFVDVRAQQVLHQFQ 534 Query: 640 KNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674 + L+ I I N+K+ PY YL P +PNS +I Sbjct: 535 ERLQEIEQRIVLCNEKRLEPYTYLLPSNVPNSTSI 569 >4G32-A nrPDB Length = 688 Score = 204 bits (518), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 156/480 (32%), Positives = 226/480 (47%), Gaps = 46/480 (9%) Query: 223 VMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNI 282 V + +++D F Y + G NP+LIRR LP P+ E + SL + + Sbjct: 227 VADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRL 286 Query: 283 FIVDFELLDGIDANKTDPCTLQ---FLAAPICL--LYKNLANKIVPIAIQLNQIPGDENP 337 +++D+ L + + L F API L L K+ A ++P+AIQ Q P +P Sbjct: 287 YLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAG-LLPVAIQCGQDPA-THP 344 Query: 338 IFL-PSDAKYD----WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHP 392 +F+ P++++ D W +AK V+ ++ + H+ HL +THLVSE F +A R L HP Sbjct: 345 MFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHP 404 Query: 393 IFKLLVAHVRFTIAINTKAREQLICECGLFD--------KANATGGGGHVQM-VQRAMKD 443 + LL H T+ IN A L+ G D AT GG + R M Sbjct: 405 LHVLLAPHFEGTLFINEGAARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGM-- 462 Query: 444 LTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEED 503 PE++KAR ++ +P Y YRDDGLLVW AIR + A+ V +YY D V D Sbjct: 463 -------LPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTAD 515 Query: 504 PELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCS 563 EL +V +V G K +GF + + R QL E LT+VIFTASAQHAAVNF Q + Sbjct: 516 VELAAWVGEVIGSG----KVAGF-RPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMT 570 Query: 564 WIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPE 623 + P AP P + + + +P + + L LG Y + Sbjct: 571 YAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGR--LGDYRQ 628 Query: 624 EHFIEKPV---------KEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674 F PV + RF+ L+ + + I RN+ ++ PY YL P RIP S I Sbjct: 629 TGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 688 >1RRL-A nrPDB Length = 857 Score = 189 bits (480), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 159/510 (31%), Positives = 243/510 (47%), Gaps = 72/510 (14%) Query: 227 WQEDLMFGYQFLNGCNPVLIRRCTELPEKLP------------VTTEMVECSLERQLSLE 274 W D F + L G NP LIR + P + +T E +E +LE L+++ Sbjct: 358 WMTDEEFAREMLAGVNPNLIRCLKDFPPRSKLDSQVYGDHTSQITKEHLEPNLE-GLTVD 416 Query: 275 QEVQQGNIFIVD-----FELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLN 329 + +Q +F++D L I+A T + A L KN + P+AI+L+ Sbjct: 417 EAIQNKRLFLLDHHDPIMPYLRRINATST-----KAYATRTILFLKN-DGTLRPLAIELS 470 Query: 330 QIP---GDENP----IFLPSDAKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVF 379 +P GD++ +FLP+D + WLLAK +V +D HQ ++H L TH V E F Sbjct: 471 -LPHPQGDQSGAFSQVFLPADEGVESSIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPF 529 Query: 380 GIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQR 439 IA R L VHPI+KLL H R T+ IN AR L+ + G+ ++ G V+M Sbjct: 530 IIATNRHLSVVHPIYKLLHPHYRDTMNINGLARLSLVNDGGVIEQT-FLWGRYSVEMSAV 588 Query: 440 AMKDLTYASLCFPEAIKARGMESKED---------IPYYFYRDDGLLVWEAIRTFTAEVV 490 KD + P + RGM ++ I Y Y DGL +W+AI+T+ E V Sbjct: 589 VYKDWVFTDQALPADLIKRGMAIEDPSCPHGIRLVIEDYPYTVDGLEIWDAIKTWVHEYV 648 Query: 491 DIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQ 550 +YY+ D + EDPELQ ++ G +K+ + +++RE+L E ++I+TASA Sbjct: 649 FLYYKSDDTLREDPELQACWKELVEVGHGDKKNEPWWPKMQTREELVEACAIIIWTASAL 708 Query: 551 HAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQI--------VDTLPDRGRSCWHL 602 HAAVNFGQY + I N P R P KG E++ + T+ + ++ L Sbjct: 709 HAAVNFGQYPYGGLILNRPTLSRRFMP-EKGSAEYEELRKNPQKAYLKTITPKFQTLIDL 767 Query: 603 GAVWALSQFQENELFLGMYPEEHFI-EKPVKEAMARFRKNLEAIVSVIAERNKKK----- 656 + LS+ +E++LG ++ + EA RF L I + ++ERN + Sbjct: 768 SVIEILSRHASDEVYLGERDNPNWTSDTRALEAFKRFGNKLAQIENKLSERNNDEKLRNR 827 Query: 657 ----QLPYYYLSPDR--------IPNSVAI 674 Q+PY L P IPNS++I Sbjct: 828 CGPVQMPYTLLLPSSKEGLTFRGIPNSISI 857 >2IUJ-A nrPDB Length = 853 Score = 186 bits (471), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 157/509 (30%), Positives = 236/509 (46%), Gaps = 69/509 (13%) Query: 227 WQEDLMFGYQFLNGCNPVLIRRCTELP--EKLP----------VTTEMVECSLERQLSLE 274 W D F + + G NP +I+ E P KL +T E +E +L L++E Sbjct: 353 WMTDEEFARETIAGLNPNVIKIIEEFPLSSKLDTQAYGDHTCIITKEHLEPNL-GGLTVE 411 Query: 275 QEVQQGNIFIVD-----FELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLN 329 Q +Q +FI+D L I+AN T + A KN + P+AI+L+ Sbjct: 412 QAIQNKKLFILDHHDYLIPYLRKINANTT-----KTYATRTIFFLKN-DGTLTPLAIELS 465 Query: 330 QI--PGDE----NPIFLPSDA---KYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFG 380 + G+E + +++PS Y WLLAK +V +D HQ I+H L TH V E F Sbjct: 466 KPHPQGEEYGPVSEVYVPSSEGVEAYIWLLAKAYVVVNDACYHQIISHWLNTHAVVEPFV 525 Query: 381 IAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRA 440 IA R L VHPI+KLL H R T+ IN+ AR+ L+ G+ +K G ++M Sbjct: 526 IATNRHLSVVHPIYKLLFPHYRDTMNINSLARKSLVNADGIIEKT-FLWGRYSLEMSAVI 584 Query: 441 MKDLTYASLCFPEAIKARGMESKED---------IPYYFYRDDGLLVWEAIRTFTAEVVD 491 KD + P + RG+ K+ I Y Y DGL +W+AI+++ E V Sbjct: 585 YKDWVFTDQALPNDLVKRGVAVKDPSAPHGVRLLIEDYPYASDGLEIWDAIKSWVEEYVS 644 Query: 492 IYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQH 551 YY+ D+ +++DPELQ + ++ G K + + +++RE+L E +I+ ASA H Sbjct: 645 FYYKSDEELQKDPELQAWWKELVEVGHGDLKDKPWWQKMQTREELVEASATLIWIASALH 704 Query: 552 AAVNFGQYDWCSWIPNAP-------PTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGA 604 AAVNFGQY + I N P P +P A ++ + T+ + + L Sbjct: 705 AAVNFGQYPYGGLILNRPTISRRFMPEKGSPEYDALAKNPEKEFLKTITGKKETLIDLTI 764 Query: 605 VWALSQFQENELFLGMYPEEHFIEKPVK--EAMARFRKNLEAIVSVIAERNKKKQL---- 658 + LS+ +E +LG + EA RF KNLE I + E+N + L Sbjct: 765 IEILSRHASDEFYLGQRDGGDYWTSDAGPLEAFKRFGKNLEEIEKKLIEKNNDETLRNRY 824 Query: 659 -----PYYYLSPDR--------IPNSVAI 674 PY L P IPNS++I Sbjct: 825 GPAKMPYTLLYPSSEEGLTFRGIPNSISI 853 >2IUK-A nrPDB Length = 864 Score = 171 bits (434), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 146/503 (29%), Positives = 228/503 (45%), Gaps = 63/503 (12%) Query: 230 DLMFGYQFLNGCNPVLIRRCTELPEKLP------------VTTEMVECSLERQLSLEQEV 277 D F + + G NP +IRR E P K +T E +E ++ +++E+ + Sbjct: 367 DEEFAREVIAGVNPNVIRRLQEFPPKSTLDPTLYGDQTSTITKEQLEINMG-GVTVEEAL 425 Query: 278 QQGNIFIVDFE--LLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIP--- 332 +FI+D++ + + + P + I L + + P+AI+L++ Sbjct: 426 STQRLFILDYQDAFIPYLTRINSLPTAKAYATRTILFLKDD--GTLKPLAIELSKPHPDG 483 Query: 333 ---GDENPIFLPSDAKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQ 386 G E+ + LP+ D WLLAK V +D HQ ++H L TH V E F IA R Sbjct: 484 DNLGPESIVVLPATEGVDSTIWLLAKAHVIVNDSGYHQLVSHWLNTHAVMEPFAIATNRH 543 Query: 387 LPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTY 446 L +HPI+KLL H R TI IN AR+ LI G+ +K+ G ++M K+ + Sbjct: 544 LSVLHPIYKLLYPHYRDTININGLARQSLINADGIIEKSFLPGKYS-IEMSSSVYKNWVF 602 Query: 447 ASLCFPEAIKARGMESKED---------IPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGD 497 P + RG+ ++ I Y Y DGL +W+AI+T+ E V +YY D Sbjct: 603 THQALPADLVKRGLAIEDPSAPHGLRLVIEDYPYAVDGLEIWDAIKTWVHEYVSLYYPTD 662 Query: 498 QVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFG 557 V++D ELQ + + G K + ++ E L + +++++TASA HAAVNFG Sbjct: 663 AAVQQDTELQAWWKEAVEKGHGDLKEKPWWPKKQTTEDLIQSCSIIVWTASALHAAVNFG 722 Query: 558 QYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVD--------TLPDRGRSCWHLGAVWALS 609 QY + I N P R P A+G +++V T+ + + L + LS Sbjct: 723 QYPYGGLILNRPTLARRFIP-AEGTPEYDEMVKNPQKAYLRTITPKFETLIDLSVIEILS 781 Query: 610 QFQENELFLGMYPEEHF-IEKPVKEAMARFRKNLEAIVSVIAERNKKK---------QLP 659 + +E++LG ++ +K EA RF L I I RN QLP Sbjct: 782 RHASDEIYLGERETPNWTTDKKALEAFKRFGSKLTGIEGKINARNSDPSLRNRTGPVQLP 841 Query: 660 YYYLSPDR--------IPNSVAI 674 Y L IPNS++I Sbjct: 842 YTLLHRSSEEGLTFKGIPNSISI 864 >4WFO-A nrPDB Length = 858 Score = 158 bits (400), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 139/508 (27%), Positives = 221/508 (43%), Gaps = 68/508 (13%) Query: 227 WQEDLMFGYQFLNGCNPVLIRRCTELPEKLPV--------TTEMVECSLERQ-LSLEQEV 277 W D F + + G NP +IR E P K + ++++ SL+ ++++ + Sbjct: 359 WMTDEEFAREMIAGVNPCVIRGLEEFPPKSNLDPAIYGDQSSKITADSLDLDGYTMDEAL 418 Query: 278 QQGNIFIVDFE--------LLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLN 329 +F++D+ ++ +++ KT + I L ++ K V I + L Sbjct: 419 GSRRLFMLDYHDIFMPYVRQINQLNSAKT------YATRTILFLREDGTLKPVAIELSLP 472 Query: 330 QIPGDENP----IFLPSDAKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIA 382 GD + + LP+ + WLLAK +V +D HQ ++H L TH E F IA Sbjct: 473 HSAGDLSAAVSQVVLPAKEGVESTIWLLAKAYVIVNDSCYHQLMSHWLNTHAAMEPFVIA 532 Query: 383 MYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMK 442 +R L +HPI+KLL H R + IN AR+ LI G+ + V+M K Sbjct: 533 THRHLSVLHPIYKLLTPHYRNNMNINALARQSLINANGIIETTFLPSKYS-VEMSSAVYK 591 Query: 443 DLTYASLCFPEAIKARGMESKED---------IPYYFYRDDGLLVWEAIRTFTAEVVDIY 493 + + P + RG+ K+ I Y Y DGL +W AI+T+ E V +Y Sbjct: 592 NWVFTDQALPADLIKRGVAIKDPSTPHGVRLLIEDYPYAADGLEIWAAIKTWVQEYVPLY 651 Query: 494 YEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAA 553 Y D V+ D ELQ + + G K + +++ E L E ++I+ ASA HAA Sbjct: 652 YARDDDVKNDSELQHWWKEAVEKGHGDLKDKPWWPKLQTLEDLVEVCLIIIWIASALHAA 711 Query: 554 VNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVD--------TLPDRGRSCWHLGAV 605 VNFGQY + I N P R P KG E++++ T+ + + L + Sbjct: 712 VNFGQYPYGGLIMNRPTASRRLLP-EKGTPEYEEMINNHEKAYLRTITSKLPTLISLSVI 770 Query: 606 WALSQFQENELFLGMYPEEHFI-EKPVKEAMARFRKNLEAIVSVIAERNKKK-------- 656 LS +E++LG H+ + +A +F L+ I + RN Sbjct: 771 EILSTHASDEVYLGQRDNPHWTSDSKALQAFQKFGNKLKEIEEKLVRRNNDPSLQGNRLG 830 Query: 657 --QLPYYYLSPDR--------IPNSVAI 674 QLPY L P IPNS++I Sbjct: 831 PVQLPYTLLYPSSEEGLTFRGIPNSISI 858 >6NS2-A nrPDB Length = 769 Score = 113 bits (282), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 121/526 (23%), Positives = 221/526 (42%), Gaps = 92/526 (17%) Query: 133 RKELETRQKQYRWMEWNPGFP--LSIDAKCHKDLPRDIQ---------------FDSEKG 175 ++EL+ +++ Y+W + G+P L +D +LP D + FD ++ Sbjct: 132 KRELDLKKRIYQWSDGTDGYPPHLKVDGNDEANLPADERQSKPGSARSEGVGQIFDMQET 191 Query: 176 VDFVLNYSKAMENLFINRFMHMFQS-SWNDFADFEKI----FVKISNTISER-------- 222 FV ++A+ + H AD EK F K S + Sbjct: 192 A-FVSKIAQAVSFIIPKDIDHENTPYKGPTLADVEKFNKAQFPKTDGDASNQDNLNKAAD 250 Query: 223 VM--------NHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLE 274 +M + W D F Q +G NP I ++ K ++ E + L++ ++ Sbjct: 251 IMKGRNIGEYDDWYSDARFAQQHFSGVNPSTIETASQDKIKEYIS-EAQKQGLDKVKAIL 309 Query: 275 QEVQQGNIFIVD---FELLDGIDANKTDPCTL--------------QFLAAPICLLYKNL 317 ++ + +I I D F G + T+ ++ AA + + + Sbjct: 310 EDGK--DILIQDYSYFREATGATNEQIFQNTVYELKGTTPTGKTTSRYAAASVVIFQLHE 367 Query: 318 ANKIVPIAIQLNQIPGDENPIFL------PSDA-------KYDWLLAKIWVRSSDFHVHQ 364 ++ P+AI L+ +N I + P D + W AK +++D+ H+ Sbjct: 368 DGRLHPLAITLDYKGSLDNSITIFNRRLSPDDTCDIAEKEDWPWRYAKTVAQTADWARHE 427 Query: 365 TITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDK 424 THL+ TH++ E +A R +P ++++L H T+++N AR+ L+ G+ + Sbjct: 428 VATHLVDTHMIEEAIIVATNRIIPEGELLYEILSPHWFRTLSLNAAARKLLV--PGVIAR 485 Query: 425 ANATG---------GGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKED----IPYYFY 471 G G +++ + K+ + P +K RG + K D Y Y Sbjct: 486 IAGFGPTSPSLDFKGNNAFKLIDWSYKNFNFQDKYIPNDLKKRGFDIKGDKSGKYKNYPY 545 Query: 472 RDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVK 531 +D L+W IR F V++ Y D VV++DP + + ++ G + FP ++ Sbjct: 546 ANDMYLLWGIIRNFVKTVIESQYTSDHVVQKDPYIGGWCKEIQTNG----QIPTFP-TIT 600 Query: 532 SREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPP 577 + EQL + +T+ I TAS QH AVN+ Q + S++P PP + P P Sbjct: 601 TVEQLIDAVTMCIHTASPQHTAVNYLQDYYYSFVPAKPPALCTPLP 646 >5FNO-A nrPDB Length = 605 Score = 100 bits (248), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 106/423 (25%), Positives = 187/423 (44%), Gaps = 43/423 (10%) Query: 191 INRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCT 250 ++ F ++Q W + I+ ++ DL+F + L+ NP +++R Sbjct: 124 LDDFKVLYQDGWKG---------SVPQGIARGQSENYTSDLLFSMERLS-VNPYILKRLH 173 Query: 251 ELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGID--ANK-TDPCTLQFLA 307 + LP + + SL+ G +F+ D AN+ + CT F Sbjct: 174 PTEDALPFQVDRATVKQLTKTSLKALHAAGRLFVADHSYQRNYTRLANRYSAACTALFYL 233 Query: 308 APICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTIT 367 P +N+ +P+AI+ N + D L +D +WLLAKI ++D H I Sbjct: 234 DP-------RSNQFLPLAIKTN-VGADLTYTPLDTDNN-NWLLAKIMFNNNDL-FHGQIF 283 Query: 368 HLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANA 427 H+ H ++E+ +A R + A HP+ L+ + A+ L + GLF++ A Sbjct: 284 HVAYPHAIAEIVHLAALRTMSARHPVLALMERLMYQAYAVRPLGERVLFNKGGLFEQNFA 343 Query: 428 TGGGGHVQMVQRAMKDLTYASLCFPEA------IKARGMESKE---DIPYYFYRDDGLLV 478 MV + + D +Y + A ++ARG+ + ++P++ + +DG + Sbjct: 344 Y----PQDMVYKFVGD-SYPTTGRWRAGYLDTDVRARGLVDADYGPELPHFPFYEDGSRL 398 Query: 479 WEAIRTFTAEVVD-IYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLS 537 E IR F VD Y+E D++V +D ELQ +V + G G + P + +RE+L Sbjct: 399 VEVIRRFVRSFVDATYHESDEMVAKDAELQAWVAE--ANGPAGVEDFE-PGPLDTRERLV 455 Query: 538 EYLTVVIFTASAQHAAVNFGQYDWCSWI-PNAPPTMRAPPPTAKGVVTIEQIVDTLPDRG 596 E LT + + H +N G+ S + P P + AP PT+K T + ++ LP Sbjct: 456 EVLTHMAWLTGCAHHVLNQGEPVTASGVLPMHPTALYAPVPTSKANTTAD-LLGYLPSAQ 514 Query: 597 RSC 599 +S Sbjct: 515 KSV 517 >5FX8-A nrPDB Length = 618 Score = 91.7 bits (226), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 98/386 (25%), Positives = 166/386 (43%), Gaps = 35/386 (9%) Query: 214 KISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSL 273 + IS+ ++++ DL+F + L+ NP +++R +KLP + E +L Sbjct: 145 SVPEGISKGMLSNCTSDLLFSMERLS-SNPYVLKRLHPTKDKLPFSVESKVVKKLTATTL 203 Query: 274 EQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNL-ANKIVPIAIQLNQIP 332 E + G +F+VD K P ++ AA L Y + +N+ +P+AI+ N Sbjct: 204 EALHKGGRLFLVDHSY-----QKKYTPQPGRYAAACQGLFYLDARSNQFLPLAIKTNV-- 256 Query: 333 GDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHP 392 + + P D K DWLLAKI ++D Q + H+L H + E+ A +R L HP Sbjct: 257 -GVDLTYTPLDDKDDWLLAKIMFNNNDLFYSQ-MYHVL-FHTIPEIVHEAAFRTLSDRHP 313 Query: 393 IFKLLVAHVRFTIAINTKAREQLICECGLFDK------ANATGGGGHVQMVQRAMKDLTY 446 + +L + AI L G +D+ + A G V Y Sbjct: 314 VMGVLNRLMYQAYAIRPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQGGGGFQAGY 373 Query: 447 ASLCFPEAIKARGM---ESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQ----V 499 + +++RG+ +S +P++ + +D + AIR F VD Y D Sbjct: 374 ----LEKDLRSRGLIGEDSGPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTYGADDGDDGA 429 Query: 500 VEEDPELQDFVNDVYVYGMRGRKSSGFPKS-VKSREQLSEYLTVVIFTASAQHAAVNFGQ 558 + D ELQ+++ + + FP + ++ R QL + LT V + H +N G Sbjct: 430 LLRDYELQNWIAEANGPA----QVRDFPAAPLRRRAQLVDVLTHVAWITGGAHHVMNQGS 485 Query: 559 -YDWCSWIPNAPPTMRAPPPTAKGVV 583 + +P P + AP PTAKG Sbjct: 486 PVKFSGVLPLHPAALYAPIPTAKGAT 511 >5EK8-A nrPDB Length = 668 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/210 (22%), Positives = 86/210 (40%), Gaps = 28/210 (13%) Query: 228 QEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDF 287 + D F + LNG NP L++R P + ++ + + E+ E ++ + V Sbjct: 245 RSDEYFVLRVLNGMNPCLLKRSKSDPNQFKMS--FIWDNYEK--DTEHDLHNVEAYFV-- 298 Query: 288 ELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYD 347 L DG L + + + + P + P + ++ P+D + Sbjct: 299 -LKDGK------------LFPTMITIQSRYPDSLAPHS------PLKDREVYTPNDGE-K 338 Query: 348 WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAI 407 WL AK R++ + I H + H+ E + +A +R L +PI +L H++ I I Sbjct: 339 WLQAKRIFRTAALFDGEAIEHYAKAHVQMEQYAVACFRNL-RKNPIRLMLTPHLKSIINI 397 Query: 408 NTKAREQLI-CECGLFDKANATGGGGHVQM 436 N + + L+ GLF G +QM Sbjct: 398 NRRGDDLLVEPNLGLFVTNGPLTYPGFLQM 427 >1KHO-A nrPDB Length = 370 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 4/71 (5%) Query: 8 VATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE---ELGE 64 + TG + +AGTDDY+Y + G +++ +D P NDF G+ D+Y + + ++ + Sbjct: 262 ITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPG-NDFMTGSQDTYTFKLKDKNLKIDD 320 Query: 65 IQLVRIEKRKY 75 IQ + I K KY Sbjct: 321 IQNMWIRKSKY 331 >2WXU-A nrPDB Length = 370 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 4/71 (5%) Query: 8 VATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEE---LGE 64 ++T + AGTDDY+Y + G +++ +D P NDF G+ D+Y + +E + + Sbjct: 262 ISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPG-NDFMTGSKDTYTFKLKDENLKIDD 320 Query: 65 IQLVRIEKRKY 75 IQ + I KRKY Sbjct: 321 IQNMWIRKRKY 331 >1OLP-A nrPDB Length = 370 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 5/102 (4%) Query: 16 AGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTV---DEELGEIQLVRIEK 72 AGTD+YIY + G E+ LD P NDF R +Y + + + + +I+ + I Sbjct: 270 AGTDNYIYFGIETKDGVKEEWALDNPG-NDFTRNQEGTYTLKLKNKNTKYSDIKNMWIRD 328 Query: 73 RKYWL-NDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113 K + D W Y+ + +E WI+G L+ Sbjct: 329 EKLTVATDGWKPSYVKVIAGDKVRLEKNINEWISGGTTYTLK 370 >1PHP-A nrPDB Length = 394 Score = 34.7 bits (78), Expect = 0.15, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 304 QFLAAPICLLYKNLANKIVPIAIQLNQIPGD----ENPIFLPSDAKYDWLLAKIWVRSSD 359 + L P+ + + +++ +LN+ GD EN F P + K D LAK + +D Sbjct: 82 ELLERPVAKTNEAVGDEVKAAVDRLNE--GDVLLLENVRFYPGEEKNDPELAKAFAELAD 139 Query: 360 FHVHQTITHLLRTHLVSEVFGIAMYRQLPAV 390 +V+ R H +E GIA Y LPAV Sbjct: 140 LYVNDAFGAAHRAHASTE--GIAHY--LPAV 166 >1VPE-A nrPDB Length = 398 Score = 33.1 bits (74), Expect = 0.41, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 4/56 (7%) Query: 335 ENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAV 390 EN F P + K D LAK W +D HV+ R H + GIA + +P+V Sbjct: 114 ENTRFHPGETKNDPELAKFWASLADIHVNDAFGTAHRAH--ASNVGIAQF--IPSV 165 >5ZCR-A nrPDB Length = 728 Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 42/76 (55%), Gaps = 5/76 (6%) Query: 211 IFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQ 270 I+V+ +I+E++ + W+ D GY FLN N +L+ E E+L T+ E + R+ Sbjct: 266 IYVEKILSINEKLRDDWKVDGTTGYDFLNYVNMLLVDGSGE--EEL---TKFYENFIGRK 320 Query: 271 LSLEQEVQQGNIFIVD 286 +++++ + Q + + Sbjct: 321 INIDELIIQSKKLVAN 336 >4V8D-BP nrPDB Length = 141 Score = 28.9 bits (63), Expect = 7.3, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 25/35 (71%) Query: 615 ELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVI 649 ++F+ ++P++ + +KP++ M + + N+E V+V+ Sbjct: 63 KIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVV 97 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3O8Y-A nrPDB 990 0.0 2P0M-A nrPDB 867 0.0 2FNQ-A nrPDB 844 0.0 4NRE-A nrPDB 817 0.0 3VF1-A nrPDB 807 0.0 3RDE-A nrPDB 727 0.0 3D3L-A nrPDB 646 0.0 5MEF-A nrPDB 570 e-163 1RRL-A nrPDB 550 e-157 2IUK-A nrPDB 535 e-152 2IUJ-A nrPDB 533 e-152 4WFO-A nrPDB 526 e-150 4G32-A nrPDB 485 e-137 6NS2-A nrPDB 426 e-119 5FNO-A nrPDB 397 e-111 5FX8-A nrPDB 390 e-109 5EK8-A nrPDB 177 1e-44 1KHO-A nrPDB 94 2e-19 2WXU-A nrPDB 93 4e-19 Sequences not found previously or not previously below threshold: 1OLP-A nrPDB 70 3e-12 5ZCR-A nrPDB 36 0.042 6BHR-G nrPDB 32 0.72 4FLV-A nrPDB 32 0.83 5TEO-A nrPDB 32 1.1 5O2U-A nrPDB 32 1.1 3OIC-A nrPDB 31 1.4 3BI4-A nrPDB 31 1.6 5IM3-A nrPDB 30 3.0 6B5C-A nrPDB 30 4.3 6MZM-G nrPDB 29 5.9 6F3T-A nrPDB 29 5.9 >3O8Y-A nrPDB Length = 691 Score = 990 bits (2560), Expect = 0.0, Method: Composition-based stats. Identities = 660/674 (97%), Positives = 661/674 (98%), Gaps = 3/674 (0%) Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60 MPSYTVTVATGSQ AGTDDYIYLSLVGSAGCSEKHLLDK FERGAVDSYDVTVDE Sbjct: 21 MPSYTVTVATGSQEHAGTDDYIYLSLVGSAGCSEKHLLDK---GSFERGAVDSYDVTVDE 77 Query: 61 ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA 120 ELGEIQLVRIEKRKY NDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA Sbjct: 78 ELGEIQLVRIEKRKYGSNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA 137 Query: 121 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL 180 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL Sbjct: 138 RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL 197 Query: 181 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG 240 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG Sbjct: 198 NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG 257 Query: 241 CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP 300 NPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP Sbjct: 258 ANPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP 317 Query: 301 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF 360 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF Sbjct: 318 CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF 377 Query: 361 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG 420 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG Sbjct: 378 HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG 437 Query: 421 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE 480 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE Sbjct: 438 LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE 497 Query: 481 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL 540 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL Sbjct: 498 AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL 557 Query: 541 TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW 600 TVVIFTASAQHAAVNFGQYDW SWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW Sbjct: 558 TVVIFTASAQHAAVNFGQYDWASWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW 617 Query: 601 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY 660 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERN+ QLPY Sbjct: 618 HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNENLQLPY 677 Query: 661 YYLSPDRIPNSVAI 674 YYLSPDRIPNSVAI Sbjct: 678 YYLSPDRIPNSVAI 691 >2P0M-A nrPDB Length = 662 Score = 867 bits (2240), Expect = 0.0, Method: Composition-based stats. Identities = 260/675 (38%), Positives = 390/675 (57%), Gaps = 19/675 (2%) Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63 Y V V+TG+ +AG+ + + L LVG G E +P N E + V V + LG Sbjct: 3 YRVCVSTGASIYAGSKNKVELWLVGQHGEVELGSCLRPTRNKEEE-----FKVNVSKYLG 57 Query: 64 EIQLVRIEKRKYWLNDDWYLKYITLKTPHG--DYIEFPCYRWITGDVEVVLRDGRAKLAR 121 + VR+ K+ + D W+ +I+++ D FPCYRW+ GD L G Sbjct: 58 SLLFVRLRKKHFLKEDAWFCNWISVQALGAAEDKYWFPCYRWVVGDGVQSLPVGTGCTTV 117 Query: 122 DDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLN 181 D + ++HR +ELE R+K Y+W W G L++ DLP D +F +K +DF + Sbjct: 118 GDPQGLFQKHREQELEERRKLYQWGSWKEGLILNVAGSKLTDLPVDERFLEDKKIDFEAS 177 Query: 182 YSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGC 241 + + L + +++ W DF +IF + ++ RV + WQED +FGYQFLNG Sbjct: 178 LAWGLAELALKNSLNILAP-WKTLDDFNRIFWCGRSKLARRVRDSWQEDSLFGYQFLNGA 236 Query: 242 NPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPC 301 NP+L+RR +LP +L M E Q LE+E++ G +F DF LLD I AN C Sbjct: 237 NPMLLRRSVQLPARLVFPPGMEEL----QAQLEKELKAGTLFEADFALLDNIKANVILYC 292 Query: 302 TLQFLAAPICLLYKNLANKIVPIAIQLN--QIPGDENPIFLPSDAKYDWLLAKIWVRSSD 359 Q+LAAP+ +L K++P+ IQL+ +I P+FLP+D WLLAK WVRSSD Sbjct: 293 Q-QYLAAPLVMLKLQPDGKLMPMVIQLHLPKIGSSPPPLFLPTDPPMVWLLAKCWVRSSD 351 Query: 360 FHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICEC 419 F VH+ +HLLR HL++EVF +A R LP++HP+FKL+V H+R+T+ IN +AR L+ + Sbjct: 352 FQVHELNSHLLRGHLMAEVFTVATMRCLPSIHPVFKLIVPHLRYTLEINVRARNGLVSDF 411 Query: 420 GLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVW 479 G+FD+ +TGGGGHVQ++Q+A LTY S C P+ + RG+ + FY D L +W Sbjct: 412 GIFDQIMSTGGGGHVQLLQQAGAFLTYRSFCPPDDLADRGLLG---VESSFYAQDALRLW 468 Query: 480 EAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEY 539 E I + ++ +YY+ D+ V +D ELQ + ++ G++G + GFP S++S Q + Sbjct: 469 EIISRYVQGIMGLYYKTDEAVRDDLELQSWCREITEIGLQGAQKQGFPTSLQSVAQACHF 528 Query: 540 LTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSC 599 +T+ IFT + QH++++ GQ DW +W+PNAP TMR PPPT K T+E ++ TLP+ +S Sbjct: 529 VTMCIFTCTGQHSSIHLGQLDWFTWVPNAPCTMRLPPPTTKD-ATLETVMATLPNLHQSS 587 Query: 600 WHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLP 659 + VW L + Q + LG + EE+F + + +FR+ L + I RN+K +P Sbjct: 588 LQMSIVWQLGRDQPIMVPLGQHQEEYFSGPEPRAVLEKFREELAIMDKEIEVRNEKLDIP 647 Query: 660 YYYLSPDRIPNSVAI 674 Y YL P + NSVAI Sbjct: 648 YEYLRPSIVENSVAI 662 >2FNQ-A nrPDB Length = 699 Score = 844 bits (2180), Expect = 0.0, Method: Composition-based stats. Identities = 273/695 (39%), Positives = 411/695 (59%), Gaps = 28/695 (4%) Query: 4 YTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELG 63 Y V V TG + AGTD I + + G+ G ++ LDK F+NDFE G+ + Y V ++G Sbjct: 9 YNVEVETGDREHAGTDATITIRITGAKGRTDYLKLDKWFHNDFEAGSKEQYTVQ-GFDVG 67 Query: 64 EIQLVRIE--KRKYWLND-DWYLKYITLKTPHGDY-IEFPCYRWITGDVEVVLRDGRAKL 119 +IQL+ + YW D DW++ + + + D FPC+RW+ D+ VL G A L Sbjct: 68 DIQLIELHSDGGGYWSGDPDWFVNRVIIISSTQDRVYSFPCFRWVIKDM--VLFPGEATL 125 Query: 120 ARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFV 179 ++ I+ + R+KELE R+ Y+W + P +I AK H DLPRD+QF EK + Sbjct: 126 PFNEVPAIVSEQRQKELEQRKLTYQWDYVSDDMPGNIKAKTHDDLPRDVQFTDEKSRSYQ 185 Query: 180 LNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLN 239 + A+ NL I MF++ W+ + D+ ++ + + + W ED FGYQFLN Sbjct: 186 ESRKAALVNLGIGSLFTMFEN-WDSYDDYHILYRNWILGGTPNMADRWHEDRWFGYQFLN 244 Query: 240 GCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI------ 293 G NPV++ RC LP PVT E V SL+R +L++E++ G+I+IVDF++L G Sbjct: 245 GANPVILTRCDALPSNFPVTNEHVNASLDRGKNLDEEIKDGHIYIVDFKVLVGAKSYGGP 304 Query: 294 ----------DANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLP-S 342 D K D +++ AAP+ L Y N ++PIAIQ+NQ PG ENPI+ P Sbjct: 305 VLEDIGYKVPDHLKHDEADIRYCAAPLALFYVNKLGHLMPIAIQINQEPGPENPIWTPHE 364 Query: 343 DAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVR 402 + ++DW++AK W+ ++ + HQ THLLRTHL +E F ++ +R L + HP+FKLL H+ Sbjct: 365 ENEHDWMMAKFWLGVAESNFHQLNTHLLRTHLTTESFALSTWRNLASAHPVFKLLQPHIY 424 Query: 403 FTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMES 462 +AI+T R++LI G+ D++ + GGGGHV +++ K++ P A+K RG++ Sbjct: 425 GVLAIDTIGRKELIGSGGIVDQSLSLGGGGHVTFMEKCFKEVNLQDYHLPNALKKRGVDD 484 Query: 463 KEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMR--- 519 +P ++YRDDGL +WEAI TF E++ I+Y+ D V+ D E+Q ++ DV+ G R Sbjct: 485 PSKLPGFYYRDDGLALWEAIETFIGEIIAIFYKNDDDVKRDNEIQSWIYDVHKNGWRVNP 544 Query: 520 GRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTA 579 G + G P S +SREQL E LT ++FT S QHAAVNF Q D + PNAP +R PPP Sbjct: 545 GHQDHGVPASFESREQLKEVLTSLVFTFSCQHAAVNFSQKDHYGFTPNAPAVLRHPPPKK 604 Query: 580 KGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFR 639 KG T++ I+ TLP + ++ + V+ L++F E+E +LG Y + +K +A+ RF+ Sbjct: 605 KGEATLQSILSTLPSKSQAAKAIATVYILTKFSEDERYLGNYSATAWEDKDALDAINRFQ 664 Query: 640 KNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674 LE I I +RN+ ++PY YL P+RIPN AI Sbjct: 665 DKLEDISKKIKQRNENLEVPYIYLLPERIPNGTAI 699 >4NRE-A nrPDB Length = 696 Score = 817 bits (2111), Expect = 0.0, Method: Composition-based stats. Identities = 288/682 (42%), Positives = 426/682 (62%), Gaps = 14/682 (2%) Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60 M + V V+TG + AGT D + +S+VG+ G S LD +F GA + + VT+ E Sbjct: 21 MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDN-LGKEFTAGAEEDFQVTLPE 79 Query: 61 ELGEIQLVRIEKRKYWLN-------DDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113 ++G + L+R+ K L D W+ ++ L P G ++ FPCY+W+ G +VL+ Sbjct: 80 DVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQ 139 Query: 114 DGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSE 173 +G AK++ D +L+Q R++EL+ RQ+ Y+W +NPG+P +D K +DL +I++ + Sbjct: 140 EGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTA 199 Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233 K +F L A + I + + W + ++IF +E HWQED F Sbjct: 200 KNANFYLQAGSAFAEMKIKGLLDR-KGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFF 258 Query: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293 QFLNG NPVLIRRC LP+ PVT MV L SL+ E+++G++F+VD +L GI Sbjct: 259 ASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGI 318 Query: 294 DANKTDPCTLQFLAAPICLLYKNLA-NKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAK 352 N + QF AAP+ LLY++ ++P+AIQL+Q PG +PIFLP+D K+DWLLAK Sbjct: 319 QTNVIN-GKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAK 377 Query: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412 WVR+++F H+ +THLL +HL+ EVF +A RQLP HP+FKLL+ H R+T+ INT AR Sbjct: 378 TWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLAR 437 Query: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472 E LI + D++ G G +++QR MK L Y+ LC PE I+ RG+ EDIP Y+YR Sbjct: 438 ELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGV---EDIPGYYYR 494 Query: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532 DDG+ +W A+ F +E++ IYY D+ V++D ELQ +V +++ G ++SSG P S+++ Sbjct: 495 DDGMQIWGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLET 554 Query: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592 RE L +Y+T+VIFT SA+HAAV+ GQ+D C+W+PN PP+M+ PPPT+KG+ T E + TL Sbjct: 555 REALVQYVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATL 614 Query: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652 P +C + A+W LS+ ++ LG YP+EHF E+ + ++A F+ L I I ER Sbjct: 615 PPVNATCDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQER 674 Query: 653 NKKKQLPYYYLSPDRIPNSVAI 674 N+ LPY YL P I NSV+I Sbjct: 675 NQGLVLPYTYLDPPLIENSVSI 696 >3VF1-A nrPDB Length = 698 Score = 807 bits (2083), Expect = 0.0, Method: Composition-based stats. Identities = 249/686 (36%), Positives = 385/686 (56%), Gaps = 22/686 (3%) Query: 3 SYTVTVATGSQWFAGTDDYIYLSLVGSAG-CSEKHLLDKPFYNDFERGAVDSYDVTVDEE 61 Y +TV TG AGTD + + L G G + LDK F+NDFE G D+YD + + Sbjct: 21 KYKITVETGDLRGAGTDASVSIKLTGKDGAETSAFSLDKYFHNDFESGGTDTYDQS-GVD 79 Query: 62 LGEIQLVRIEKRKYWLNDDWYLKYITLK-----TPHGDYIEFPCYRWITGDVEVVLRDGR 116 +GEI ++ +++ + L DWY+ + ++ T + FPCYRW+ ++V+ +G+ Sbjct: 80 VGEIAMITLKENGFGLKSDWYIAKVIIEKIDEATGFSNKYIFPCYRWVIK--QLVVYEGK 137 Query: 117 AKLARD-DQIHILKQHRRKELETRQKQYRWME---WNPGFPLSIDAKCHKDLPRDIQFDS 172 A L D + + + R KE+ +K Y+W + P +DA+ K LP+D+QF Sbjct: 138 AILPNSKDNVKTIAEQRTKEVSENKKLYKWGTDPRYVQDLPGFVDAEEPKSLPKDVQFTD 197 Query: 173 EKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLM 232 E NL ++ ++ W+ DF ++ + +W++D+ Sbjct: 198 EATSSLFRVGLADFANLGLSHLFGIW-DDWDCLEDFRQLITPAIKSGLPHAAEYWRDDVW 256 Query: 233 FGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDG 292 FG QFLNG NP +IRRC +LPE PV EMVE L+R +LE+ +++G IFI D+++L+G Sbjct: 257 FGSQFLNGSNPEVIRRCDKLPENFPVKNEMVEKLLDRGYTLEKAMKEGLIFITDYKILEG 316 Query: 293 IDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLP-SDAKYDWLLA 351 I T P +++ P+ L Y + I+PIAIQL Q PG+ N I+ P D ++DW++A Sbjct: 317 IPTMDT-PEDKRYITTPLGLFYLKNNDDIIPIAIQLYQQPGENNSIWTPLKDTEWDWIMA 375 Query: 352 KIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKA 411 K+W+R +D HQ ITHLLR HL+ E ++ +R LP+VHP++KLL H + +AINT Sbjct: 376 KLWLRCADTQYHQMITHLLRCHLMMEPTAVSSWRNLPSVHPVWKLLYPHTKGIMAINTLG 435 Query: 412 REQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFY 471 R LI G DK + GGGG V ++Q+ + +T+ S + ++ RG++ + ++Y Sbjct: 436 RNDLIPTGGAADKVLSIGGGGQVTLMQKHYRSVTFDSYDLVKDLRQRGVDG---LRKFYY 492 Query: 472 RDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGM---RGRKSSGFPK 528 +DD LL+W I F +++ IYY D V++D E+QD++ D++ G PK Sbjct: 493 KDDALLLWNVIHQFVQDIIQIYYNDDDSVKKDNEIQDWIRDLHENGYPAGSDGTDKKVPK 552 Query: 529 SVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQI 588 S ++RE+L +LTVV+FT S QHAAVNF Q + PN+P MR PPPT KG + I Sbjct: 553 SFENREELVHFLTVVVFTCSCQHAAVNFSQMATYGFHPNSPTLMRQPPPTEKGKSNHKVI 612 Query: 589 VDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSV 648 + +L ++ ++ + V AL+ E FLG Y + F + AMA+F+ NL I Sbjct: 613 MASLANKHQAVTMVSVVNALTTIYPTEKFLGDYADNLFGDAAAHAAMAKFKSNLANITKQ 672 Query: 649 IAERNKKKQLPYYYLSPDRIPNSVAI 674 I ERN+ PY +L P +PNS+AI Sbjct: 673 ITERNQGMVSPYTWLIPGHVPNSIAI 698 >3RDE-A nrPDB Length = 573 Score = 727 bits (1877), Expect = 0.0, Method: Composition-based stats. Identities = 232/562 (41%), Positives = 339/562 (60%), Gaps = 12/562 (2%) Query: 115 GRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEK 174 G A+ DD + K+HR +EL R+K YRW W G L+I + DLP D +F +K Sbjct: 22 GTARTVVDDPQGLFKKHREEELAERRKLYRWGNWKDGLILNIASTGIHDLPVDERFLEDK 81 Query: 175 GVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFG 234 +DF + +K + +L + +++ S WN F +IF + ++ERV + W+ED +FG Sbjct: 82 RIDFEASLAKGLADLAVKDSLNVLMS-WNSLDSFNRIFWSGQSKLAERVRDSWKEDALFG 140 Query: 235 YQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGID 294 YQFLNG NP+L+R ELP +L M E Q LE+E+Q G +F DF LLDGI Sbjct: 141 YQFLNGTNPMLLRHSVELPARLKFPPGMEEL----QAQLEKELQGGTLFEADFSLLDGIK 196 Query: 295 ANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQL--NQIPGDENPIFLPSDAKYDWLLAK 352 AN + Q+LA P+ +L K++P+ IQL + P+FLP+D WLLAK Sbjct: 197 ANVIL-SSQQYLAVPLVMLKLQPDGKLLPMVIQLQLPREGSPLPPLFLPTDPPMVWLLAK 255 Query: 353 IWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAR 412 WVRSSDF +H+ +HLLR HL++EV +A R LP++HPIFKLL+ H R+T+ IN +AR Sbjct: 256 CWVRSSDFQLHELHSHLLRGHLMAEVIAVATMRCLPSIHPIFKLLIPHFRYTMEINVRAR 315 Query: 413 EQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYR 472 L+ + G+FD+ +TGGGGHV++++RA LTY+S C P+ + RG+ + FY Sbjct: 316 NGLVSDLGIFDQVVSTGGGGHVELLRRAAALLTYSSFCPPDDLADRGLLG---VESSFYA 372 Query: 473 DDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS 532 D L +WE I + +V ++Y+ D+ V+ED ELQ + + G+ G + GFP S++S Sbjct: 373 QDALRLWEVISRYVEGIVSLHYKTDESVKEDFELQAWCREFTEIGLLGAQDRGFPVSLQS 432 Query: 533 REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTL 592 +EQL ++T+ IFT + QH++ + GQ DW +W+PNAP TMR PPPT K T+E ++ TL Sbjct: 433 KEQLCHFVTMCIFTCTGQHSSNHLGQLDWYTWVPNAPCTMRLPPPTTKD-ATLETVMATL 491 Query: 593 PDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAER 652 P+ ++ + W L + Q + LG + EE+F K + +FR+ L A+ I R Sbjct: 492 PNFHQASLQMSITWQLGRCQPTMVALGQHEEEYFSGPGPKAVLTKFREELAALDKDIEVR 551 Query: 653 NKKKQLPYYYLSPDRIPNSVAI 674 N K LPY YL P R+ NSVAI Sbjct: 552 NAKLALPYEYLRPSRVENSVAI 573 >3D3L-A nrPDB Length = 541 Score = 646 bits (1666), Expect = 0.0, Method: Composition-based stats. Identities = 212/502 (42%), Positives = 303/502 (60%), Gaps = 11/502 (2%) Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMF 233 + +DF + + R + SSWN DF++IF + ++E+V WQ+D +F Sbjct: 16 ENLDFEWTLKAGALEMALKRVYTLL-SSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELF 74 Query: 234 GYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293 YQFLNG NP+L+RR T LP +L + + M E LE+E+Q G++F DF LLDGI Sbjct: 75 SYQFLNGANPMLLRRSTSLPSRLVLPSGMEELR----AQLEKELQNGSLFEADFILLDGI 130 Query: 294 DANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENP--IFLPSDAKYDWLLA 351 AN Q+LAAP+ +L K+ P+ IQ+ +FLPSD WLLA Sbjct: 131 PANVIR-GEKQYLAAPLVMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLA 189 Query: 352 KIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKA 411 K WVR+SDF +H+ HLL THLV+EV +A R LP +HPIFK L+ H+R+T+ INT+A Sbjct: 190 KSWVRNSDFQLHEIQYHLLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRA 249 Query: 412 REQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFY 471 R QLI + G+FDKA +TGGGGHVQ+++RA LTY SLC P+ + RG+ +P Y Sbjct: 250 RTQLISDGGIFDKAVSTGGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLG---LPGALY 306 Query: 472 RDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVK 531 D L +WE I + +V ++Y+ D +V+ DPELQ + ++ G+ + GFP S + Sbjct: 307 AHDALRLWEIIARYVEGIVHLFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQ 366 Query: 532 SREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDT 591 S+ QL +LT+ +FT +AQHAA+N GQ DW +W+PNAP TMR PPPT K VT+ ++ + Sbjct: 367 SQSQLCHFLTMCVFTCTAQHAAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGS 426 Query: 592 LPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAE 651 LPD ++C + W LS+ Q + + LG + E++F K + +FR +LE + I Sbjct: 427 LPDVRQACLQMAISWHLSRRQPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITA 486 Query: 652 RNKKKQLPYYYLSPDRIPNSVA 673 RN++ PY YL P I NSV Sbjct: 487 RNEQLDWPYEYLKPSCIENSVT 508 >5MEF-A nrPDB Length = 569 Score = 570 bits (1470), Expect = e-163, Method: Composition-based stats. Identities = 168/585 (28%), Positives = 290/585 (49%), Gaps = 50/585 (8%) Query: 119 LARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDF 178 L +DD ++ R + + +++ Y++ E + K LP+ F + + Sbjct: 6 LPQDDTPDQ-QEQRNRAIAQQREAYQYSE-------TAGILLIKTLPQSEMF----SLKY 53 Query: 179 VLNYSKAMENLFINRFMHMFQSSWNDFA---DFEKIFVKISNTISERVMNHWQEDLMFGY 235 ++ K + +L N ++ ++ F DFE++F + + VMN ++ D +F Sbjct: 54 LIERDKGLVSLIANTLASNIENIFDPFDKLEDFEEMFPLLPKPL---VMNTFRNDRVFAR 110 Query: 236 QFLNGCNPVLIRRC-TELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGID 294 Q + G NP++I R +LP+ PVT M + + + +L + + QG +FI +++ L + Sbjct: 111 QRIAGPNPMVIERVVDKLPDNFPVTDAMFQKIMFTKKTLAEAIAQGKLFITNYKGLAELS 170 Query: 295 A-------NKTDPCTLQFLAAPICLL------YKNLANKIVPIAIQLNQIPGD-ENPIFL 340 N T + +AAP+ L + + + PIAIQ+NQ P NPI+ Sbjct: 171 PGRYEYQKNGTLVQKTKTIAAPLVLYAWKPEGFGDYRGSLAPIAIQINQQPDPITNPIYT 230 Query: 341 PSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAH 400 P D K+ W +AKI+ + +D + H+ I+HL RTHL+ E F +A +L HP+ LL H Sbjct: 231 PRDGKH-WFIAKIFAQMADGNCHEAISHLARTHLILEPFVLATANELAPNHPLSVLLKPH 289 Query: 401 VRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDL--TYASLCFPEAIKAR 458 +FT+AIN AREQ I G D A + +++ A+K+ + P + R Sbjct: 290 FQFTLAINELAREQFISAGGYADDLLAGTLEASIAVIKAAIKEYMDNFTEFALPRELARR 349 Query: 459 GM-------ESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVN 511 G+ + +P Y YRDD +L+W AI + + + +YY+ + +D ELQ++V Sbjct: 350 GVGIGDVDQRGENFLPDYPYRDDAMLLWNAIEVYVRDYLSLYYQSPVQIRQDTELQNWVR 409 Query: 512 DVYVYGMRGRKSSGFPKS--VKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAP 569 + G + +G + + + E L T VIF + QHAAVN+ QYD+ ++IPN P Sbjct: 410 RLV--SPEGGRVTGLVSNGELNTIEALVAIATQVIFVSGPQHAAVNYPQYDYMAFIPNMP 467 Query: 570 PTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEK 629 A PP + ++ I++ LP + + L + L F N L YP+ F++ Sbjct: 468 LATYATPPNKESNISEATILNILPPQKLAARQLELMRTLCVFYPNRL---GYPDTEFVDV 524 Query: 630 PVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674 ++ + +F++ L+ I I N+K+ PY YL P +PNS +I Sbjct: 525 RAQQVLHQFQERLQEIEQRIVLCNEKRLEPYTYLLPSNVPNSTSI 569 >1RRL-A nrPDB Length = 857 Score = 550 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 170/609 (27%), Positives = 266/609 (43%), Gaps = 107/609 (17%) Query: 164 LPRDIQFDSEKGVDFVLNYSKAMEN----LFINRFMHMFQS-SWNDFADFEKIFV---KI 215 LPRD F K DF+ K++ L + F F ++ F + ++ K+ Sbjct: 258 LPRDEAFGHLKSSDFLTYGLKSVSQNVLPLLQSAFDLNFTPREFDSFDEVHGLYSGGIKL 317 Query: 216 SNTISERVM-----------------------------NHWQEDLMFGYQFLNGCNPVLI 246 I ++ + W D F + L G NP LI Sbjct: 318 PTDIISKISPLPVLKEIFRTDGEQALKFPPPKVIQVSKSAWMTDEEFAREMLAGVNPNLI 377 Query: 247 RRCTELPEKLP------------VTTEMVECSLERQLSLEQEVQQGNIFIVDF-----EL 289 R + P + +T E +E +LE L++++ +Q +F++D Sbjct: 378 RCLKDFPPRSKLDSQVYGDHTSQITKEHLEPNLE-GLTVDEAIQNKRLFLLDHHDPIMPY 436 Query: 290 LDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIP------GDENPIFLPSD 343 L I+A T A +L+ + P+AI+L+ G + +FLP+D Sbjct: 437 LRRINATSTK------AYATRTILFLKNDGTLRPLAIELSLPHPQGDQSGAFSQVFLPAD 490 Query: 344 AKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAH 400 + WLLAK +V +D HQ ++H L TH V E F IA R L VHPI+KLL H Sbjct: 491 EGVESSIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPFIIATNRHLSVVHPIYKLLHPH 550 Query: 401 VRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGM 460 R T+ IN AR L+ + G+ ++ G V+M KD + P + RGM Sbjct: 551 YRDTMNINGLARLSLVNDGGVIEQTF-LWGRYSVEMSAVVYKDWVFTDQALPADLIKRGM 609 Query: 461 ESKED---------IPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVN 511 ++ I Y Y DGL +W+AI+T+ E V +YY+ D + EDPELQ Sbjct: 610 AIEDPSCPHGIRLVIEDYPYTVDGLEIWDAIKTWVHEYVFLYYKSDDTLREDPELQACWK 669 Query: 512 DVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPT 571 ++ G +K+ + +++RE+L E ++I+TASA HAAVNFGQY + I N P Sbjct: 670 ELVEVGHGDKKNEPWWPKMQTREELVEACAIIIWTASALHAAVNFGQYPYGGLILNRPTL 729 Query: 572 MRAPPPTAKGVVTIEQI--------VDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPE 623 R P KG E++ + T+ + ++ L + LS+ +E++LG Sbjct: 730 SRRFMP-EKGSAEYEELRKNPQKAYLKTITPKFQTLIDLSVIEILSRHASDEVYLGERDN 788 Query: 624 EHFI-EKPVKEAMARFRKNLEAIVSVIAERNKKK---------QLPYYYLSPDR------ 667 ++ + EA RF L I + ++ERN + Q+PY L P Sbjct: 789 PNWTSDTRALEAFKRFGNKLAQIENKLSERNNDEKLRNRCGPVQMPYTLLLPSSKEGLTF 848 Query: 668 --IPNSVAI 674 IPNS++I Sbjct: 849 RGIPNSISI 857 >2IUK-A nrPDB Length = 864 Score = 535 bits (1379), Expect = e-152, Method: Composition-based stats. Identities = 180/740 (24%), Positives = 294/740 (39%), Gaps = 150/740 (20%) Query: 79 DDWYLKYITLKT-PHGDYIEFPCYRWITG----DVEVVLRDGRAKLARDDQIHILKQHRR 133 D+++L + L+ P+ IEF C W+ + L +LK +R+ Sbjct: 131 DEFFLVSVKLEDIPNHGTIEFVCNSWVYNFRSYKKNRIFFVNDTYLPSATPAPLLK-YRK 189 Query: 134 KELETRQ-----------KQYRWMEWNP-------------------GFPLSIDAKCHKD 163 +E E + + Y + +N +PL + + Sbjct: 190 EEFEVLRGDGTGKRKDFDRIYDYDVYNDLGNPDGGDPRPILGGCSIYPYPLRVRTGRERT 249 Query: 164 -------------LPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMF------QSSWND 204 +PRD F K DF+ K++ + I F S + Sbjct: 250 RTDPNSEKPGEVYVPRDENFGHLKSSDFLTYGIKSLSHDVIPLFKSAIFQLRVTSSEFES 309 Query: 205 FADFEKIF---VKISNTISERVM-----------------------------NHWQEDLM 232 F D ++ +K+ I ++ + D Sbjct: 310 FEDVRSLYEGGIKLPTDILSQISPLPALKEIFRTDGENVLQFPPPHVAKVSKSGVMTDEE 369 Query: 233 FGYQFLNGCNPVLIRRCTELPEK------------LPVTTEMVECSLERQLSLEQEVQQG 280 F + + G NP +IRR E P K +T E +E ++ +++E+ + Sbjct: 370 FAREVIAGVNPNVIRRLQEFPPKSTLDPTLYGDQTSTITKEQLEINMG-GVTVEEALSTQ 428 Query: 281 NIFIVDFE--LLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIP------ 332 +FI+D++ + + + P + I L + + P+AI+L++ Sbjct: 429 RLFILDYQDAFIPYLTRINSLPTAKAYATRTILFLKDD--GTLKPLAIELSKPHPDGDNL 486 Query: 333 GDENPIFLPSDAKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPA 389 G E+ + LP+ D WLLAK V +D HQ ++H L TH V E F IA R L Sbjct: 487 GPESIVVLPATEGVDSTIWLLAKAHVIVNDSGYHQLVSHWLNTHAVMEPFAIATNRHLSV 546 Query: 390 VHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASL 449 +HPI+KLL H R TI IN AR+ LI G+ +K+ G ++M K+ + Sbjct: 547 LHPIYKLLYPHYRDTININGLARQSLINADGIIEKSFLPGKY-SIEMSSSVYKNWVFTHQ 605 Query: 450 CFPEAIKARGMESKED---------IPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVV 500 P + RG+ ++ I Y Y DGL +W+AI+T+ E V +YY D V Sbjct: 606 ALPADLVKRGLAIEDPSAPHGLRLVIEDYPYAVDGLEIWDAIKTWVHEYVSLYYPTDAAV 665 Query: 501 EEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYD 560 ++D ELQ + + G K + ++ E L + +++++TASA HAAVNFGQY Sbjct: 666 QQDTELQAWWKEAVEKGHGDLKEKPWWPKKQTTEDLIQSCSIIVWTASALHAAVNFGQYP 725 Query: 561 WCSWIPNAPPTMRAPPPTAKGVVTIEQIVD--------TLPDRGRSCWHLGAVWALSQFQ 612 + I N P R P A+G +++V T+ + + L + LS+ Sbjct: 726 YGGLILNRPTLARRFIP-AEGTPEYDEMVKNPQKAYLRTITPKFETLIDLSVIEILSRHA 784 Query: 613 ENELFLGMYPEEHF-IEKPVKEAMARFRKNLEAIVSVIAERNKKK---------QLPYYY 662 +E++LG ++ +K EA RF L I I RN QLPY Sbjct: 785 SDEIYLGERETPNWTTDKKALEAFKRFGSKLTGIEGKINARNSDPSLRNRTGPVQLPYTL 844 Query: 663 LSPDR--------IPNSVAI 674 L IPNS++I Sbjct: 845 LHRSSEEGLTFKGIPNSISI 864 >2IUJ-A nrPDB Length = 853 Score = 533 bits (1373), Expect = e-152, Method: Composition-based stats. Identities = 188/749 (25%), Positives = 306/749 (40%), Gaps = 157/749 (20%) Query: 74 KYWLNDDWYLKYITLKT-PHGDYIEFPCYRWITGD----VEVVLRDGRAKLARDDQIHIL 128 K ++ +++YLK + L+ P+ I F C W+ + + L + ++ Sbjct: 114 KNYMQNEFYLKSLILEDIPNHGTIHFICNSWVYNSKHYKTDRIFFANNTYLPSETPAPLV 173 Query: 129 KQHRRKELE--------TRQ---KQYRWMEWNP-GFPLSID------------------- 157 K +R +EL+ R+ + Y + +N G P + Sbjct: 174 K-YREEELKNVRGDGTGERKEWDRIYDYDVYNDLGDPDKGEKYARPVLGGSALPYPRRGR 232 Query: 158 ---AKCHKD-----------LPRDIQFDSEKGVDFVL----NYSKAMENLFINRFMHMFQ 199 K KD LPRD F K DF+ + ++ + + + F Sbjct: 233 TGRGKTRKDPNSEKPGDFVYLPRDEAFGHLKSSDFLAYGIKSVAQDVLPVLTDAFDGNLL 292 Query: 200 S-SWNDFADFEKIF------------VKISNTISERVM--------------------NH 226 S +++FA+ K++ I + + + Sbjct: 293 SLDFDNFAEVRKLYEGGVTLPTNFLSNITPIPIIKELFRTDGEQFLKYPPPKVMQVDKSA 352 Query: 227 WQEDLMFGYQFLNGCNPVLIRRCTELPEKLP------------VTTEMVECSLERQLSLE 274 W D F + + G NP +I+ E P +T E +E +L L++E Sbjct: 353 WMTDEEFARETIAGLNPNVIKIIEEFPLSSKLDTQAYGDHTCIITKEHLEPNLG-GLTVE 411 Query: 275 QEVQQGNIFIVDF-----ELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLN 329 Q +Q +FI+D L I+AN T + I + + P+AI+L+ Sbjct: 412 QAIQNKKLFILDHHDYLIPYLRKINANTT----KTYATRTI--FFLKNDGTLTPLAIELS 465 Query: 330 QIP------GDENPIFLPSDAKYD---WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFG 380 + G + +++PS + WLLAK +V +D HQ I+H L TH V E F Sbjct: 466 KPHPQGEEYGPVSEVYVPSSEGVEAYIWLLAKAYVVVNDACYHQIISHWLNTHAVVEPFV 525 Query: 381 IAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRA 440 IA R L VHPI+KLL H R T+ IN+ AR+ L+ G+ +K G ++M Sbjct: 526 IATNRHLSVVHPIYKLLFPHYRDTMNINSLARKSLVNADGIIEKTF-LWGRYSLEMSAVI 584 Query: 441 MKDLTYASLCFPEAIKARGMESKED---------IPYYFYRDDGLLVWEAIRTFTAEVVD 491 KD + P + RG+ K+ I Y Y DGL +W+AI+++ E V Sbjct: 585 YKDWVFTDQALPNDLVKRGVAVKDPSAPHGVRLLIEDYPYASDGLEIWDAIKSWVEEYVS 644 Query: 492 IYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQH 551 YY+ D+ +++DPELQ + ++ G K + + +++RE+L E +I+ ASA H Sbjct: 645 FYYKSDEELQKDPELQAWWKELVEVGHGDLKDKPWWQKMQTREELVEASATLIWIASALH 704 Query: 552 AAVNFGQYDWCSWIPNAPPTMRAPPP-------TAKGVVTIEQIVDTLPDRGRSCWHLGA 604 AAVNFGQY + I N P R P A ++ + T+ + + L Sbjct: 705 AAVNFGQYPYGGLILNRPTISRRFMPEKGSPEYDALAKNPEKEFLKTITGKKETLIDLTI 764 Query: 605 VWALSQFQENELFLGMYPEEHFI--EKPVKEAMARFRKNLEAIVSVIAERNKKKQL---- 658 + LS+ +E +LG + + EA RF KNLE I + E+N + L Sbjct: 765 IEILSRHASDEFYLGQRDGGDYWTSDAGPLEAFKRFGKNLEEIEKKLIEKNNDETLRNRY 824 Query: 659 -----PYYYLSPDR--------IPNSVAI 674 PY L P IPNS++I Sbjct: 825 GPAKMPYTLLYPSSEEGLTFRGIPNSISI 853 >4WFO-A nrPDB Length = 858 Score = 526 bits (1356), Expect = e-150, Method: Composition-based stats. Identities = 137/518 (26%), Positives = 220/518 (42%), Gaps = 61/518 (11%) Query: 214 KISNTISERVMNH-WQEDLMFGYQFLNGCNPVLIRRCTELPEKLPV--------TTEMVE 264 K +V W D F + + G NP +IR E P K + ++++ Sbjct: 345 KFPQPHVVQVSQSAWMTDEEFAREMIAGVNPCVIRGLEEFPPKSNLDPAIYGDQSSKITA 404 Query: 265 CSLER-QLSLEQEVQQGNIFIVDFE--LLDGIDANKTDPCTLQFLAAPICLLYKNLANKI 321 SL+ ++++ + +F++D+ + + + I L ++ + Sbjct: 405 DSLDLDGYTMDEALGSRRLFMLDYHDIFMPYVRQINQLNSAKTYATRTILFLRED--GTL 462 Query: 322 VPIAIQLNQIP------GDENPIFLPSDAKYD---WLLAKIWVRSSDFHVHQTITHLLRT 372 P+AI+L+ + + LP+ + WLLAK +V +D HQ ++H L T Sbjct: 463 KPVAIELSLPHSAGDLSAAVSQVVLPAKEGVESTIWLLAKAYVIVNDSCYHQLMSHWLNT 522 Query: 373 HLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGG 432 H E F IA +R L +HPI+KLL H R + IN AR+ LI G+ + Sbjct: 523 HAAMEPFVIATHRHLSVLHPIYKLLTPHYRNNMNINALARQSLINANGIIETTFLPSKY- 581 Query: 433 HVQMVQRAMKDLTYASLCFPEAIKARGMESKED---------IPYYFYRDDGLLVWEAIR 483 V+M K+ + P + RG+ K+ I Y Y DGL +W AI+ Sbjct: 582 SVEMSSAVYKNWVFTDQALPADLIKRGVAIKDPSTPHGVRLLIEDYPYAADGLEIWAAIK 641 Query: 484 TFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVV 543 T+ E V +YY D V+ D ELQ + + G K + +++ E L E ++ Sbjct: 642 TWVQEYVPLYYARDDDVKNDSELQHWWKEAVEKGHGDLKDKPWWPKLQTLEDLVEVCLII 701 Query: 544 IFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVD--------TLPDR 595 I+ ASA HAAVNFGQY + I N P R P KG E++++ T+ + Sbjct: 702 IWIASALHAAVNFGQYPYGGLIMNRPTASRRLLP-EKGTPEYEEMINNHEKAYLRTITSK 760 Query: 596 GRSCWHLGAVWALSQFQENELFLGMYPEEHFI-EKPVKEAMARFRKNLEAIVSVIAERNK 654 + L + LS +E++LG H+ + +A +F L+ I + RN Sbjct: 761 LPTLISLSVIEILSTHASDEVYLGQRDNPHWTSDSKALQAFQKFGNKLKEIEEKLVRRNN 820 Query: 655 KK----------QLPYYYLSPDR--------IPNSVAI 674 QLPY L P IPNS++I Sbjct: 821 DPSLQGNRLGPVQLPYTLLYPSSEEGLTFRGIPNSISI 858 >4G32-A nrPDB Length = 688 Score = 485 bits (1248), Expect = e-137, Method: Composition-based stats. Identities = 156/536 (29%), Positives = 235/536 (43%), Gaps = 50/536 (9%) Query: 169 QFDSEKGVDF-VLNYSKAMENLFINRFMHMFQSSW--NDFADFEKIFVKISNTISERVMN 225 +F + +L + + + ++ + F +F + V + Sbjct: 173 RFTELQTRVIALLTRVGLLVDDILKSASNLVTQGGQGDGLNRFRAVFGTLR---LPEVAD 229 Query: 226 HWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIV 285 +++D F Y + G NP+LIRR LP P+ E + SL + ++++ Sbjct: 230 SFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLL 289 Query: 286 DFELLDGIDANKTDPCTLQ---FLAAPICLL--YKNLANKIVPIAIQLNQIPGDENPIFL 340 D+ L + + L F API L K+ A ++P+AIQ Q P Sbjct: 290 DYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRAG-LLPVAIQCGQDPATHPMFVR 348 Query: 341 PSDAK----YDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKL 396 P++++ + W +AK V+ ++ + H+ HL +THLVSE F +A R L HP+ L Sbjct: 349 PAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVL 408 Query: 397 LVAHVRFTIAINTKAREQLICECGLFD--------KANATGGGGHVQM-VQRAMKDLTYA 447 L H T+ IN A L+ G D AT GG + R M Sbjct: 409 LAPHFEGTLFINEGAARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGM------ 462 Query: 448 SLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQ 507 PE++KAR ++ +P Y YRDDGLLVW AIR + A+ V +YY D V D EL Sbjct: 463 ---LPESLKARNVDDPAALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELA 519 Query: 508 DFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPN 567 +V +V G K +GF + + R QL E LT+VIFTASAQHAAVNF Q ++ P Sbjct: 520 AWVGEVIGSG----KVAGF-RPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPA 574 Query: 568 APPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFI 627 AP P + + + +P + + L LG Y + F Sbjct: 575 ICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGR--LGDYRQTGFP 632 Query: 628 EKPV---------KEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI 674 PV + RF+ L+ + + I RN+ ++ PY YL P RIP S I Sbjct: 633 YAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRKPYEYLLPSRIPASTNI 688 >6NS2-A nrPDB Length = 769 Score = 426 bits (1095), Expect = e-119, Method: Composition-based stats. Identities = 123/545 (22%), Positives = 225/545 (41%), Gaps = 95/545 (17%) Query: 133 RKELETRQKQYRWMEWNPGFP--LSIDAKCHKDLPRDIQ---------------FDSEKG 175 ++EL+ +++ Y+W + G+P L +D +LP D + FD ++ Sbjct: 132 KRELDLKKRIYQWSDGTDGYPPHLKVDGNDEANLPADERQSKPGSARSEGVGQIFDMQET 191 Query: 176 VDFVLNYSKAMENLFINRFMHMFQS-SWNDFADFEKI----FVKISNTISE--------- 221 FV ++A+ + H AD EK F K S Sbjct: 192 A-FVSKIAQAVSFIIPKDIDHENTPYKGPTLADVEKFNKAQFPKTDGDASNQDNLNKAAD 250 Query: 222 -------RVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLE 274 + W D F Q +G NP I ++ K ++ E + L++ ++ Sbjct: 251 IMKGRNIGEYDDWYSDARFAQQHFSGVNPSTIETASQDKIKEYIS-EAQKQGLDKVKAIL 309 Query: 275 QEVQQGNIFIVDFELLD---GIDANKTDPCTL--------------QFLAAPICLLYKNL 317 ++ + +I I D+ G + T+ ++ AA + + + Sbjct: 310 EDGK--DILIQDYSYFREATGATNEQIFQNTVYELKGTTPTGKTTSRYAAASVVIFQLHE 367 Query: 318 ANKIVPIAIQLNQIPGDENPIFL------PSD-------AKYDWLLAKIWVRSSDFHVHQ 364 ++ P+AI L+ +N I + P D + W AK +++D+ H+ Sbjct: 368 DGRLHPLAITLDYKGSLDNSITIFNRRLSPDDTCDIAEKEDWPWRYAKTVAQTADWARHE 427 Query: 365 TITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDK 424 THL+ TH++ E +A R +P ++++L H T+++N AR+ L+ G+ + Sbjct: 428 VATHLVDTHMIEEAIIVATNRIIPEGELLYEILSPHWFRTLSLNAAARKLLVP--GVIAR 485 Query: 425 ANATG---------GGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKED----IPYYFY 471 G G +++ + K+ + P +K RG + K D Y Y Sbjct: 486 IAGFGPTSPSLDFKGNNAFKLIDWSYKNFNFQDKYIPNDLKKRGFDIKGDKSGKYKNYPY 545 Query: 472 RDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVK 531 +D L+W IR F V++ Y D VV++DP + + ++ G + FP ++ Sbjct: 546 ANDMYLLWGIIRNFVKTVIESQYTSDHVVQKDPYIGGWCKEIQTNG----QIPTFP-TIT 600 Query: 532 SREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPP---TAKGVVTIEQI 588 + EQL + +T+ I TAS QH AVN+ Q + S++P PP + P P +A T + + Sbjct: 601 TVEQLIDAVTMCIHTASPQHTAVNYLQDYYYSFVPAKPPALCTPLPQDLSALQGYTEKDL 660 Query: 589 VDTLP 593 LP Sbjct: 661 TAALP 665 >5FNO-A nrPDB Length = 605 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 126/579 (21%), Positives = 232/579 (40%), Gaps = 71/579 (12%) Query: 132 RRKELETRQKQYRWM-------EWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSK 184 R E+ +Q + + PG PL DA +D + + + +K Sbjct: 52 RTAEIRLKQATLLYGPSLLGNASYFPGGPLG-DAISLRDQTVWEGAAVVQSLRAFTDAAK 110 Query: 185 AMENLF-------INRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQF 237 N+ ++ F ++Q W + I+ ++ DL+F + Sbjct: 111 VAANIKQNGGLNSLDDFKVLYQDGWKG---------SVPQGIARGQSENYTSDLLFSMER 161 Query: 238 LNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANK 297 L+ NP +++R + LP + + SL+ G +F+ D Sbjct: 162 LS-VNPYILKRLHPTEDALPFQVDRATVKQLTKTSLKALHAAGRLFVADHSYQRNYTRL- 219 Query: 298 TDPCTLQFLAAPICLLYKNL-ANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVR 356 ++ AA L Y + +N+ +P+AI+ N + D L +D +WLLAKI Sbjct: 220 ----ANRYSAACTALFYLDPRSNQFLPLAIKTN-VGADLTYTPLDTDNN-NWLLAKIMFN 273 Query: 357 SSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLI 416 ++D H I H+ H ++E+ +A R + A HP+ L+ + A+ L Sbjct: 274 NNDL-FHGQIFHVAYPHAIAEIVHLAALRTMSARHPVLALMERLMYQAYAVRPLGERVLF 332 Query: 417 CECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPE------AIKARGMESKE---DIP 467 + GLF++ A MV + + D +Y + ++ARG+ + ++P Sbjct: 333 NKGGLFEQNFAY----PQDMVYKFVGD-SYPTTGRWRAGYLDTDVRARGLVDADYGPELP 387 Query: 468 YYFYRDDGLLVWEAIRTFTAEVVD-IYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGF 526 ++ + +DG + E IR F VD Y+E D++V +D ELQ +V + G G + Sbjct: 388 HFPFYEDGSRLVEVIRRFVRSFVDATYHESDEMVAKDAELQAWVAEA--NGPAGVEDFE- 444 Query: 527 PKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWI-PNAPPTMRAPPPTAKGVVTI 585 P + +RE+L E LT + + H +N G+ S + P P + AP PT+K T Sbjct: 445 PGPLDTRERLVEVLTHMAWLTGCAHHVLNQGEPVTASGVLPMHPTALYAPVPTSKANTT- 503 Query: 586 EQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFI--------EKPVKEAMAR 637 ++ LP +S + + ++ + + F + + A R Sbjct: 504 ADLLGYLPSAQKSVDQVTLLARFNR--PDVVPTNQTLRYMFAAPQLLLGNGEAYRRANQR 561 Query: 638 FRKNLEAIVSVIAERNKKKQ-----LPYYY--LSPDRIP 669 F + + I + R + +P+ + L P IP Sbjct: 562 FVRAMGRISDEVKARRFDDRGLSQGMPFIWQALDPGNIP 600 >5FX8-A nrPDB Length = 618 Score = 390 bits (1002), Expect = e-109, Method: Composition-based stats. Identities = 123/594 (20%), Positives = 227/594 (38%), Gaps = 70/594 (11%) Query: 118 KLARDDQIHILKQHRRKELETRQKQYRWMEWNPG----FPLSIDAKCHKDLPRDIQFDSE 173 L +D + R + +++ + + G +P RD+ + Sbjct: 48 TLPNNDPN---QGARNASIARKRELFLYGPSTLGQTTFYPTGELGNNISA--RDVLLWRQ 102 Query: 174 KGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFV-----KISNTISERVMNHWQ 228 + + F + + + DF ++ + IS+ ++++ Sbjct: 103 DAANQTATAYREANETFAD---ITSRGGFKTLDDFALLYNGHWKESVPEGISKGMLSNCT 159 Query: 229 EDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFE 288 DL+F + L+ NP +++R +KLP + E +LE + G +F+VD Sbjct: 160 SDLLFSMERLS-SNPYVLKRLHPTKDKLPFSVESKVVKKLTATTLEALHKGGRLFLVDHS 218 Query: 289 LLDGIDANKTDPCTLQFLAAPICLLYKN-LANKIVPIAIQLNQIPGDENPIFLPSDAKYD 347 K P ++ AA L Y + +N+ +P+AI+ N + + P D K D Sbjct: 219 Y-----QKKYTPQPGRYAAACQGLFYLDARSNQFLPLAIKTNV---GVDLTYTPLDDKDD 270 Query: 348 WLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAI 407 WLLAKI ++D Q + H+L H + E+ A +R L HP+ +L + AI Sbjct: 271 WLLAKIMFNNNDLFYSQ-MYHVL-FHTIPEIVHEAAFRTLSDRHPVMGVLNRLMYQAYAI 328 Query: 408 NTKAREQLICECGLFDKANATGGGGHVQMVQRAM--KDLTYASLCFPEAIKARGM---ES 462 L G +D+ + + + + +++RG+ +S Sbjct: 329 RPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQGGGGFQAGYLEKDLRSRGLIGEDS 388 Query: 463 KEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQ----VVEEDPELQDFVNDVYVYGM 518 +P++ + +D + AIR F VD Y D + D ELQ+++ + Sbjct: 389 GPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTYGADDGDDGALLRDYELQNWIAEANGP-- 446 Query: 519 RGRKSSGFP-KSVKSREQLSEYLTVVIFTASAQHAAVNFGQY-DWCSWIPNAPPTMRAPP 576 + FP ++ R QL + LT V + H +N G + +P P + AP Sbjct: 447 --AQVRDFPAAPLRRRAQLVDVLTHVAWITGGAHHVMNQGSPVKFSGVLPLHPAALYAPI 504 Query: 577 PTAKGVV---TIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEE---HFIEKP 630 PTAKG T ++ LP+ ++ + L++F N +G + F Sbjct: 505 PTAKGATGNGTRAGLLAWLPNERQAVEQVS---LLARF--NRAQVGDRKQTVRDAFAAPD 559 Query: 631 VK--------EAMARFRKNLEAIVSVIAER-------NKKKQLPYYYLSPDRIP 669 + A ARF ++ I IA R ++ + L+P P Sbjct: 560 LLAGNGPGYAAANARFVEDTGRISREIAGRGFDGKGLSQGMPFVWTALNPAVNP 613 >5EK8-A nrPDB Length = 668 Score = 177 bits (449), Expect = 1e-44, Method: Composition-based stats. Identities = 70/436 (16%), Positives = 144/436 (33%), Gaps = 63/436 (14%) Query: 158 AKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVK-IS 216 + D +F + + + + + + + ++ Sbjct: 180 EETPDDYSVGRKFQAYASANVLTPIKAK------HTIANTLNPKEPSLTQIQADYPPNLT 233 Query: 217 NTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQE 276 + + + D F + LNG NP L++R P + ++ + + E+ E + Sbjct: 234 INLDREKPGYTRSDEYFVLRVLNGMNPCLLKRSKSDPNQFKMS--FIWDNYEKDT--EHD 289 Query: 277 VQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDEN 336 + + V L DG L + + + + P + P + Sbjct: 290 LHNVEAYFV---LKDGK------------LFPTMITIQSRYPDSLAPHS------PLKDR 328 Query: 337 PIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKL 396 ++ P+D + WL AK R++ + I H + H+ E + +A +R L +PI + Sbjct: 329 EVYTPNDGE-KWLQAKRIFRTAALFDGEAIEHYAKAHVQMEQYAVACFRNL-RKNPIRLM 386 Query: 397 LVAHVRFTIAINTKAREQLI-CECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAI 455 L H++ I IN + + L+ GLF G +QM + + + I Sbjct: 387 LTPHLKSIININRRGDDLLVEPNLGLFVTNGPLTYPGFLQMCTEVVATYDWKDWQPRQPI 446 Query: 456 -------KARGM--ESKEDIPYYFYRDDGLLV---WEAIRTFTAEVV--DIYYEGDQVVE 501 KA + + + F+ + W IR F+ ++V + Y+ + + Sbjct: 447 CDDHKYAKAANLYWQILTEYVDAFFAKHQQAIADEWVEIRRFSEDLVEHSMPYQPIEGIM 506 Query: 502 EDPELQDFVNDVYVYGMRGRKSSGF--------------PKSVKSREQLSEYLTVVIFTA 547 + + D + F S + L + +IF Sbjct: 507 ANTDSDYEWYDTGELDKPDLPRATFNGKTKVIRPITNSNQPSATDIDNLKQCCRHIIFHT 566 Query: 548 SAQHAAVNFGQYDWCS 563 + H VN Q D Sbjct: 567 TLWHTWVNDSQSDEGG 582 >1KHO-A nrPDB Length = 370 Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 30/106 (28%), Positives = 52/106 (49%), Gaps = 5/106 (4%) Query: 8 VATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE---ELGE 64 + TG + +AGTDDY+Y + G +++ +D P NDF G+ D+Y + + ++ + Sbjct: 262 ITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPG-NDFMTGSQDTYTFKLKDKNLKIDD 320 Query: 65 IQLVRIEKRKYW-LNDDWYLKYITLKTPHGDYIEFPCYRWITGDVE 109 IQ + I K KY DD+ I + + WI+G+ Sbjct: 321 IQNMWIRKSKYTEFGDDYKPANIKVIANGNVVLNKDINEWISGNST 366 >2WXU-A nrPDB Length = 370 Score = 92.9 bits (229), Expect = 4e-19, Method: Composition-based stats. Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 5/106 (4%) Query: 8 VATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEE---LGE 64 ++T + AGTDDY+Y + G +++ +D P NDF G+ D+Y + +E + + Sbjct: 262 ISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPG-NDFMTGSKDTYTFKLKDENLKIDD 320 Query: 65 IQLVRIEKRKY-WLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVE 109 IQ + I KRKY D + + I + ++ WI+G+ Sbjct: 321 IQNMWIRKRKYTAFPDAYKPENIKIIANGKVVVDKDINEWISGNST 366 >1OLP-A nrPDB Length = 370 Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 5/117 (4%) Query: 1 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE 60 + V + T AGTD+YIY + G E+ LD P NDF R +Y + + Sbjct: 255 LNEIVVMIKTADVQDAGTDNYIYFGIETKDGVKEEWALDNPG-NDFTRNQEGTYTLKLKN 313 Query: 61 ---ELGEIQLVRIEKRKY-WLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLR 113 + +I+ + I K D W Y+ + +E WI+G L+ Sbjct: 314 KNTKYSDIKNMWIRDEKLTVATDGWKPSYVKVIAGDKVRLEKNINEWISGGTTYTLK 370 >5ZCR-A nrPDB Length = 728 Score = 36.2 bits (82), Expect = 0.042, Method: Composition-based stats. Identities = 29/159 (18%), Positives = 60/159 (37%), Gaps = 14/159 (8%) Query: 143 YRWMEWNPGFPLSIDAKCHKDL-PRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSS 201 Y+ W G+P DL I+ D + ++ L I+ ++ Sbjct: 191 YQLTYWKKGYPNYRRFFAVNDLIAVRIELDEVFRESHEIIAKLPVDGLRIDHIDGLYNPK 250 Query: 202 WNDFADFEK-------IFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPE 254 + I+V+ +I+E++ + W+ D GY FLN N +L+ E Sbjct: 251 -EYLDKLRQLVGNDKIIYVEKILSINEKLRDDWKVDGTTGYDFLNYVNMLLVDGSGEEEL 309 Query: 255 KLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGI 293 T+ E + R++++++ + Q + + I Sbjct: 310 -----TKFYENFIGRKINIDELIIQSKKLVANQLFKGDI 343 >6BHR-G nrPDB Length = 95 Score = 32.4 bits (72), Expect = 0.72, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 25/67 (37%) Query: 487 AEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFT 546 + VD +Y+ + + E+++++ + + K++ L E +T Sbjct: 17 RDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGV 76 Query: 547 ASAQHAA 553 H A Sbjct: 77 GGPGHKA 83 >4FLV-A nrPDB Length = 793 Score = 32.0 bits (71), Expect = 0.83, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%) Query: 239 NGCN---PVLIRRCTELPEKLPVTTEMVECSLER-QLSLEQEVQQGNIFIVDFELLDGID 294 NG N P L++R +L KLP+ + E ++R SL E++ G I F ++ Sbjct: 232 NGDNFAFPYLLKRAEKLGIKLPLGRDNSEPKMQRMGDSLAVEIK-GRIHFDLFPVIRRTI 290 Query: 295 ANKTDPCTLQFLA 307 T + A Sbjct: 291 NLPTYTLEAVYEA 303 >5TEO-A nrPDB Length = 110 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 25/67 (37%) Query: 487 AEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFT 546 + VD +Y+ + + E+++++ + + K++ L E +T Sbjct: 27 RDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGV 86 Query: 547 ASAQHAA 553 H A Sbjct: 87 GGPGHKA 93 >5O2U-A nrPDB Length = 500 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 25/67 (37%) Query: 487 AEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFT 546 + VD +Y+ + + E+++++ + + K++ L E +T Sbjct: 294 RDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGV 353 Query: 547 ASAQHAA 553 H A Sbjct: 354 GGPGHKA 360 >3OIC-A nrPDB Length = 258 Score = 31.2 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 43/112 (38%), Gaps = 25/112 (22%) Query: 389 AVHPIFKLLVAHVRFTIAINTKAREQLICE-----------CGLFDKANATGG------G 431 + P+ +L H +T+ IN KA L C G ++ G Sbjct: 94 VLRPVMELEETHWDWTMNINAKA--LLFCAQEAAKLMEKNGGGHIVSISSLGSIRYLENY 151 Query: 432 GHVQMVQRAMKDLT-YASLCF-PEAIK----ARGMESKEDIPYYFYRDDGLL 477 V + + A++ LT Y ++ P+ I + G + + ++ R+D L Sbjct: 152 TTVGVSKAALEALTRYLAVELSPKQIIVNAVSGGAIDTDALKHFPNREDLLE 203 >3BI4-A nrPDB Length = 516 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 39/237 (16%), Positives = 84/237 (35%), Gaps = 38/237 (16%) Query: 63 GEIQLVR-IEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLAR 121 G +Q V + RKY + W H D + P + + ++ L DGR + Sbjct: 46 GRLQTVTGYQGRKYDIGASW----------HHDTLTNPLF---LEEAQLSLNDGRTRFVF 92 Query: 122 DDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLN 181 DD I R ++ ++ + N + + H+ L + + ++L Sbjct: 93 DDDNFIYIDEERGRVDHDKELLLEIVDNE-MSKFAELEFHQHLGVSDCSFFQLVMKYLLQ 151 Query: 182 YSKAMENLFINRF--MHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLN 239 + + N I + + W+ K+ + +D FG+Q N Sbjct: 152 RRQFLTNDQIRYLPQLCRYLELWHGLD------WKLLSA----------KDTYFGHQGRN 195 Query: 240 GC----NPVLIRRCTELPEK-LPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLD 291 + V+ R P+ L ++ E+ + E ++ + G ++ D+ ++ Sbjct: 196 AFALNYDSVVQRIAQSFPQNWLKLSCEVKSITREPSKNVTVNCEDGTVYNADYVIIT 252 >5IM3-A nrPDB Length = 963 Score = 30.1 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 19/129 (14%), Positives = 41/129 (31%), Gaps = 10/129 (7%) Query: 392 PIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCF 451 P+ + + +R + I A I ++ + + + T + Sbjct: 752 PLRERVQKGIRNS-NIMAIAPTATIANITGVSQSIEPTYQN-LYVKSNLSGEFTVINPYL 809 Query: 452 PEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQV-----VEEDPEL 506 +KARG+ + Y D + I ++ D+Y +V VE Sbjct: 810 VRDLKARGLWDPVMVNDLKYYDGSVQ---QIERIPQDLKDLYATAFEVETRWIVEAASRR 866 Query: 507 QDFVNDVYV 515 Q +++ Sbjct: 867 QKWIDQAQS 875 >6B5C-A nrPDB Length = 307 Score = 29.7 bits (65), Expect = 4.3, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 40/108 (37%), Gaps = 4/108 (3%) Query: 163 DLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISER 222 D+ ++ EK + L +K L + D + S Sbjct: 180 DIDEALRRRLEKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGA---D 236 Query: 223 VMNHWQEDLMFG-YQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLER 269 + N ++ + + +NG +P IR ++ ++PVT E +L++ Sbjct: 237 ITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKK 284 >6MZM-G nrPDB Length = 800 Score = 29.3 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 15/26 (57%) Query: 566 PNAPPTMRAPPPTAKGVVTIEQIVDT 591 PNAPP R P P K +++I++ Sbjct: 419 PNAPPQNRIPLPELKDSDKLDKIMNM 444 >6F3T-A nrPDB Length = 608 Score = 29.3 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 15/26 (57%) Query: 566 PNAPPTMRAPPPTAKGVVTIEQIVDT 591 PNAPP R P P K +++I++ Sbjct: 227 PNAPPQNRIPLPELKDSDKLDKIMNM 252 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.129 0.348 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,353,046 Number of Sequences: 36641 Number of extensions: 997733 Number of successful extensions: 2804 Number of sequences better than 10.0: 31 Number of HSP's better than 10.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 2556 Number of HSP's gapped (non-prelim): 67 length of query: 674 length of database: 10,336,785 effective HSP length: 104 effective length of query: 570 effective length of database: 6,526,121 effective search space: 3719888970 effective search space used: 3719888970 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.5 bits)