BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09914 (478 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5UDI-A nrPDB 988 0.0 4HOU-A nrPDB 572 e-163 4HOQ-A nrPDB 539 e-154 4G1T-A nrPDB 382 e-106 1W3B-A nrPDB 45 6e-05 5LVV-A nrPDB 41 0.001 5A01-A nrPDB 40 0.002 5KHR-J nrPDB 36 0.046 5WQL-B nrPDB 35 0.064 6C95-A nrPDB 31 1.00 6FO1-G nrPDB 31 1.2 5FZQ-A nrPDB 30 2.0 6MFV-A nrPDB 29 3.8 5G04-F nrPDB 29 3.9 5O6D-A nrPDB 29 4.1 5NNP-A nrPDB 29 4.4 4UZU-A nrPDB 29 5.3 5OMP-A nrPDB 29 5.7 5O09-1C nrPDB 29 5.7 1KT1-A nrPDB 28 6.0 6AF0-A nrPDB 28 6.5 4W8Y-A nrPDB 28 6.5 5MQ0-T nrPDB 28 7.8 >5UDI-A nrPDB Length = 479 Score = 988 bits (2554), Expect = 0.0, Method: Compositional matrix adjust. Identities = 476/478 (99%), Positives = 476/478 (99%) Query: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY Sbjct: 2 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 61 Query: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK Sbjct: 62 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 121 Query: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG Sbjct: 122 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 181 Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 240 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI Sbjct: 182 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 241 Query: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 300 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI Sbjct: 242 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 301 Query: 301 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE Sbjct: 302 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 361 Query: 361 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 420 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN Sbjct: 362 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 421 Query: 421 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 478 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEA EYYERA RLAADFENSVRQGP Sbjct: 422 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEAEEYYERAERLAADFENSVRQGP 479 >4HOU-A nrPDB Length = 273 Score = 572 bits (1474), Expect = e-163, Method: Compositional matrix adjust. Identities = 273/273 (100%), Positives = 273/273 (100%) Query: 7 DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 66 DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG Sbjct: 1 DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 60 Query: 67 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 126 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK Sbjct: 61 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 120 Query: 127 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 186 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY Sbjct: 121 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 180 Query: 187 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN 246 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN Sbjct: 181 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN 240 Query: 247 MSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 279 MSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ Sbjct: 241 MSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 273 >4HOQ-A nrPDB Length = 482 Score = 539 bits (1389), Expect = e-154, Method: Compositional matrix adjust. Identities = 266/464 (57%), Positives = 351/464 (75%), Gaps = 3/464 (0%) Query: 10 VKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNE 69 +K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKGQN+ Sbjct: 9 LKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNK 68 Query: 70 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 129 +AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CKKLS Sbjct: 69 DALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLS 128 Query: 130 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 189 +P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ YRLD Sbjct: 129 SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLD 188 Query: 190 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 249 + K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L +SS Sbjct: 189 DSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS 247 Query: 250 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQ 309 Q YV RYAAKFYRRK S +KALELLKKAL+ TPTS LHHQ+GLCY+AQMIQIK+AT + Sbjct: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNR 307 Query: 310 PRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369 P+G+++ K+D++I SAIFHF++A+E+ F A+ DLA MY E G + AE+ F+K L + Sbjct: 308 PKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 Query: 370 KPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRK 429 + + ++ IH+HYGRFQEF +KS+ AI HYL+A+K++ S R K ++LKKL ++ Sbjct: 368 ENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKR 427 Query: 430 LRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 L ALD++SLS LGFVYKLEG +A EYYE+A ++ D EN+ Sbjct: 428 LCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI--DPENA 469 >4G1T-A nrPDB Length = 472 Score = 382 bits (980), Expect = e-106, Method: Compositional matrix adjust. Identities = 216/471 (45%), Positives = 303/471 (64%), Gaps = 21/471 (4%) Query: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60 MS N + + ++ SL QL+CHFTW L ++ + D E++V + EF + ++ + NLLAY Sbjct: 1 MSEN-NKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAY 59 Query: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120 +KHLKGQNE AL+ L++AE L+Q+EH +QA +RSLVTWGN+AW+YYHMGRL++ Q Y+DK Sbjct: 60 LKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDK 119 Query: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180 V+++C+K S+P YR+E PE+DCEEGW LKCGG ERAK CFEK LE P+NPE ++G Sbjct: 120 VKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSG 177 Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQD----EGQEAEG 236 AI++YRLD + + ++ PLRQA+RLNPDN Y+KVLLALKL +E EG Sbjct: 178 LAIASYRLDNWPPSQN-----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEG 232 Query: 237 EKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK 296 EK +EEAL T V R AAKFYRRK DKA+ELLKKAL+ P + LH QIG CY+ Sbjct: 233 EKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYR 292 Query: 297 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPT-FEVAHLDLARMYIEAGN 355 A++ Q+ + G + KL ++I A+ H + A E F V + LA ++ A Sbjct: 293 AKVFQVMNLRENGMYG--KRKLLELIGHAVAHLKKADEANDNLFRVCSI-LASLHALADQ 349 Query: 356 HRKAEENFQKLLC--MKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASL 413 + +AE FQK + PV + Q +H YG FQ +Q K + AI H+++ +KI Q S Sbjct: 350 YEEAEYYFQKEFSKELTPVAK---QLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSR 406 Query: 414 TRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL 464 ++K + L+K+ +L + D E+L +L F+ +L M +A E ER L Sbjct: 407 EKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGL 457 >1W3B-A nrPDB Length = 388 Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 65/280 (23%), Positives = 110/280 (39%), Gaps = 48/280 (17%) Query: 207 RQAVRLNPD--NGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRY-AAKFYRR 263 R A+RL PD +GYI + AL + E + Y+ N Y R + Sbjct: 91 RHALRLKPDFIDGYINLAAALVAAGD-MEGAVQAYVSALQYN--PDLYCVRSDLGNLLKA 147 Query: 264 KGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIR 323 G +++A KA++ P + +G + AQ G+ I Sbjct: 148 LGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQ-------------GE--------IW 186 Query: 324 SAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEETMQDI 380 AI HFE AV P F A+++L + EA +A + + L + P VV + + Sbjct: 187 LAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACV 246 Query: 381 HFHYGRFQEFQKKSDVNAIIHYLKAIKIE----------QASLTRDKSINSLKKLVLRKL 430 ++ G AI Y +AI+++ +L S+ + L Sbjct: 247 YYEQGLIDL--------AIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTAL 298 Query: 431 RRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADF 470 R +SL+ L + + +GN+ EA+ Y +AL + +F Sbjct: 299 RLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEF 338 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 6/84 (7%) Query: 387 FQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFV 446 Q ++++ D ++ L +I + L R ++L +++ L E+ S LG V Sbjct: 23 MQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLA------IKQNPLLAEAYSNLGNV 76 Query: 447 YKLEGNMNEALEYYERALRLAADF 470 YK G + EA+E+Y ALRL DF Sbjct: 77 YKERGQLQEAIEHYRHALRLKPDF 100 Score = 32.3 bits (72), Expect = 0.47, Method: Compositional matrix adjust. Identities = 55/255 (21%), Positives = 104/255 (40%), Gaps = 42/255 (16%) Query: 149 LLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQ 208 LLK G+ E AKAC+ K +E P +A++ L G + ++ + Sbjct: 144 LLKALGR-LEEAKACYLKAIETQP-------NFAVAWSNL-GCVFNAQGEIWLAIHHFEK 194 Query: 209 AVRLNPD--NGYIK---VLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRR 263 AV L+P+ + YI VL ++ D A Y+ AL+ + V A Y Sbjct: 195 AVTLDPNFLDAYINLGNVLKEARIFDRAVAA----YLR-ALSLSPNHAVVHGNLACVYYE 249 Query: 264 KGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNR-------- 315 +G +D A++ ++A++ P H C A ++ K + N Sbjct: 250 QGLIDLAIDTYRRAIELQP-----HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTH 304 Query: 316 -EKLDKM---------IRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQK 365 + L+ + I A+ + A+E P F AH +LA + + G ++A ++++ Sbjct: 305 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKE 364 Query: 366 LLCMKPVVEETMQDI 380 + + P + ++ Sbjct: 365 AIRISPTFADAYSNM 379 Score = 31.6 bits (70), Expect = 0.87, Method: Compositional matrix adjust. Identities = 31/149 (20%), Positives = 64/149 (42%), Gaps = 29/149 (19%) Query: 322 IRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIH 381 ++ AI H+ A+ KP F +++LA + AG+ A + + L P + Sbjct: 83 LQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDL-------- 134 Query: 382 FHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLS 441 + +SD+ ++ L ++E+A K+I + + + S Sbjct: 135 --------YCVRSDLGNLLKALG--RLEEAKACYLKAIETQPNFAV-----------AWS 173 Query: 442 LLGFVYKLEGNMNEALEYYERALRLAADF 470 LG V+ +G + A+ ++E+A+ L +F Sbjct: 174 NLGCVFNAQGEIWLAIHHFEKAVTLDPNF 202 >5LVV-A nrPDB Length = 749 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/127 (24%), Positives = 61/127 (48%), Gaps = 13/127 (10%) Query: 258 AKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ------MIQIKEATKGQP- 310 A R +G++++A+ L +KAL+ P H + + Q ++ KEA + P Sbjct: 37 ANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 96 Query: 311 ------RGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQ 364 N K + ++ A+ + A++ P F AH +LA ++ ++GN +A +++ Sbjct: 97 FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYR 156 Query: 365 KLLCMKP 371 L +KP Sbjct: 157 TALKLKP 163 Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust. Identities = 34/152 (22%), Positives = 64/152 (42%), Gaps = 29/152 (19%) Query: 322 IRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIH 381 I A+ + A+E P F AH +LA + + G ++A ++++ + + P + ++ Sbjct: 46 IEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMG 105 Query: 382 FHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLS 441 Q+ Q A+ Y +AI+I A ++ S Sbjct: 106 NTLKEMQDVQ-----GALQCYTRAIQINPAFA------------------------DAHS 136 Query: 442 LLGFVYKLEGNMNEALEYYERALRLAADFENS 473 L ++K GN+ EA+ Y AL+L DF ++ Sbjct: 137 NLASIHKDSGNIPEAIASYRTALKLKPDFPDA 168 >5A01-A nrPDB Length = 710 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 15/128 (11%) Query: 258 AKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ------MIQIKEATKGQPR 311 A R +G +++A L KAL+ P H + + Q ++ KEA + QP Sbjct: 14 ANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPT 73 Query: 312 --------GQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENF 363 G ++L + A+ + A++ P F AH +LA ++ ++GN +A +++ Sbjct: 74 FADAYSNMGNTLKELQD-VSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSY 132 Query: 364 QKLLCMKP 371 + L +KP Sbjct: 133 RTALKLKP 140 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 36/143 (25%), Positives = 65/143 (45%), Gaps = 31/143 (21%) Query: 332 AVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGR-FQEF 390 A+E P F AH +LA + + G ++A ++++ + ++P T D + + G +E Sbjct: 33 ALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQP----TFADAYSNMGNTLKEL 88 Query: 391 QKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLE 450 Q S A+ Y +AI+I A ++ S L ++K Sbjct: 89 QDVS--GALQCYTRAIQINPAFA------------------------DAHSNLASIHKDS 122 Query: 451 GNMNEALEYYERALRLAADFENS 473 GN+ EA++ Y AL+L DF ++ Sbjct: 123 GNIPEAIQSYRTALKLKPDFPDA 145 >5KHR-J nrPDB Length = 620 Score = 35.8 bits (81), Expect = 0.046, Method: Compositional matrix adjust. Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 21/152 (13%) Query: 342 AHLDLARMYIEAG---NHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNA 398 HL + + +E G N + AE F + L + P M ++ FQ + K+ Sbjct: 367 CHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGV--VAFQNGEWKTAEKW 424 Query: 399 IIHYLKAIKIEQASLTRDKSINSLKKL--VLRKLR---------RKALDL-----ESLSL 442 + L+ IK +T DK L L V RKL+ R+AL L + S Sbjct: 425 FLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSA 484 Query: 443 LGFVYKLEGNMNEALEYYERALRLAADFENSV 474 +G+++ L GN A++Y+ AL L D SV Sbjct: 485 IGYIHSLMGNFENAVDYFHTALGLRRDDTFSV 516 >5WQL-B nrPDB Length = 278 Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust. Identities = 46/180 (25%), Positives = 67/180 (37%), Gaps = 32/180 (17%) Query: 128 LSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYR 187 S R + PE+ G L + G N++ A F+ VLE+DP + I+ Y Sbjct: 69 FSQALAIRPDMPEVFNYLGIYLTQAG--NFDAAYEAFDSVLELDPTYNYAHLNRGIALYY 126 Query: 188 LDGFKLATKN---------HKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEK 238 KLA + + PF L L A + D K +L + +E G Sbjct: 127 GGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQ-KLDEKQAKEVLKQHFEKSDKEQWGWN 185 Query: 239 YIEEALANMSSQTYVFR--------------------YAAKFYRRKGSVDKALELLKKAL 278 +E L N+S QT + R Y K+Y G +D A L K A+ Sbjct: 186 IVEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAV 245 >6C95-A nrPDB Length = 866 Score = 31.2 bits (69), Expect = 1.00, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 248 SSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATK 307 ++ +V Y A+ Y + G ALE + A++ TPT + L YK IKEA + Sbjct: 371 TTLLWVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYK-HAGNIKEAAR 429 Query: 308 GQPRGQNREKLDKMIRS 324 Q + D+ I S Sbjct: 430 WMDEAQALDTADRFINS 446 >6FO1-G nrPDB Length = 665 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 5/59 (8%) Query: 141 IDCEEGWALLKCGGK-----NYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLA 194 +D ++ L + G K Y+ A C+ K ++ DP NP A + +RL F +A Sbjct: 128 VDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVA 186 >5FZQ-A nrPDB Length = 131 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 4/75 (5%) Query: 206 LRQAVRLNPDNGYIKVL--LALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRR 263 +R+AV L+P+N IK L LA L EG+ E KY+ +A++ + A + Sbjct: 28 MRKAVSLDPNN--IKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAVLLAQ 85 Query: 264 KGSVDKALELLKKAL 278 +G ++A++ ++KA+ Sbjct: 86 EGKAEEAIKYMRKAV 100 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 28/42 (66%), Gaps = 4/42 (9%) Query: 206 LRQAVRLNPDNGYIKVL--LALKLQDEGQEAEGEKYIEEALA 245 +R+AV L+P+N IK L LA+ L EG+ E KY+ +A++ Sbjct: 62 MRKAVSLDPNN--IKTLSNLAVLLAQEGKAEEAIKYMRKAVS 101 >6MFV-A nrPDB Length = 653 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 15/122 (12%) Query: 13 SLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEAL 72 +L +LR + + +D P + R+L ++E D Y+ +A ++ +G E+A+ Sbjct: 335 NLVELRVKEFYRIIVD---FPRMYQRLLMEVE--DNPYA---KIEIAIIEVQRGLFEKAI 386 Query: 73 KSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPF 132 K LKEAE + E + + +W A+M + L +A+ YL K + I +K+++ + Sbjct: 387 KLLKEAEPYVDEFFKCE-----IYSWLADAYM--ELENLEKAERYLKKTKEIVEKINDMY 439 Query: 133 RY 134 + Sbjct: 440 AW 441 >5G04-F nrPDB Length = 824 Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust. Identities = 45/181 (24%), Positives = 73/181 (40%), Gaps = 35/181 (19%) Query: 158 ERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNG 217 ++A ACF + V+P + + G + Y+ + F LA + ++A+ +NP + Sbjct: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH--------FQKALDINPQSS 669 Query: 218 YIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYV--FRYAAKFYRRKGSVDKALELLK 275 + L G K E+AL ++ + KF+R SV A E K Sbjct: 670 VL-------LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHR--ASVLFANEKYK 720 Query: 276 KALQE-------TPTSVLLHHQIGLCYKA------QMIQIKEATKGQPRGQN---REKLD 319 ALQE P L++ IG YK ++ A P+G N +E +D Sbjct: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 Query: 320 K 320 K Sbjct: 781 K 781 >5O6D-A nrPDB Length = 545 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 56 NLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSL 95 ++ ++K +K +E L+++K E LMQ H N A R L Sbjct: 382 SVFDFMKRVKTDDEVVLENIKRKEQLMQTIHQNSAGKRRL 421 >5NNP-A nrPDB Length = 745 Score = 29.3 bits (64), Expect = 4.4, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 6/98 (6%) Query: 208 QAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYV-FRYAAKFYRRKGS 266 Q ++ NP +G + AL L +G+ E +EAL + ++Y+ + YR + Sbjct: 35 QILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEAL-TIDMKSYICWHVYGILYRTNKN 93 Query: 267 VDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKE 304 D+A++ K AL+ P S HQI IQ+++ Sbjct: 94 FDEAIKAYKFALKLEPES----HQIQRDLAVLQIQMRD 127 >4UZU-A nrPDB Length = 513 Score = 28.9 bits (63), Expect = 5.3, Method: Compositional matrix adjust. Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 33/118 (27%) Query: 97 TWGNFAWMYYHMGRLAEAQTYLDKVE-NICKKLSNPFRYRMECP--EIDCEEGWALLKCG 153 T+ +F W +YH D V+ + +KLS +++R + E+D E G Sbjct: 150 TYSSFKWRWYH----------FDGVDWDESRKLSRIYKFRGKAWDWEVDTEFG------- 192 Query: 154 GKNYERAKACFEKVLEVDPENPE------SSAGYAISAYRLDGFKLATKNHKPFSLLP 205 NY+ + ++D ++PE + + ++ +DGF+L H FS P Sbjct: 193 --NYD-----YLMYADLDMDHPEVVTELKNWGKWYVNTTNIDGFRLDAVKHIKFSFFP 243 >5OMP-A nrPDB Length = 462 Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 15/18 (83%) Query: 157 YERAKACFEKVLEVDPEN 174 +E AK FEKVLEV+P+N Sbjct: 372 FESAKGDFEKVLEVNPQN 389 >5O09-1C nrPDB Length = 238 Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 30/44 (68%), Gaps = 2/44 (4%) Query: 428 RKLRRKALDLES--LSLLGFVYKLEGNMNEALEYYERALRLAAD 469 ++LR++ DL + SLL +Y G M++A E+YE AL+++A+ Sbjct: 64 QELRKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFYELALKISAE 107 >1KT1-A nrPDB Length = 457 Score = 28.5 bits (62), Expect = 6.0, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 15/18 (83%) Query: 157 YERAKACFEKVLEVDPEN 174 +E AK FEKVLEV+P+N Sbjct: 367 FESAKGDFEKVLEVNPQN 384 >6AF0-A nrPDB Length = 939 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 19/28 (67%) Query: 157 YERAKACFEKVLEVDPENPESSAGYAIS 184 Y RA F+K L++DP+N ++ G AI+ Sbjct: 721 YNRAVEFFDKALQLDPKNAYAAQGIAIA 748 >4W8Y-A nrPDB Length = 888 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 23/34 (67%), Gaps = 2/34 (5%) Query: 46 LDTKYSVGIHNLLAY--VKHLKGQNEEALKSLKE 77 +DT VGI +L + ++H++G+N+E K L+E Sbjct: 816 VDTWPKVGIDEMLKFEVIRHIRGRNKEETKELRE 849 >5MQ0-T nrPDB Length = 877 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 18/24 (75%) Query: 258 AKFYRRKGSVDKALELLKKALQET 281 AK+Y +G +D +LLKK+LQ+T Sbjct: 310 AKYYISRGRLDSCGDLLKKSLQQT 333 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5UDI-A nrPDB 758 0.0 4HOQ-A nrPDB 669 0.0 4G1T-A nrPDB 601 e-172 4HOU-A nrPDB 474 e-134 1W3B-A nrPDB 258 5e-69 5A01-A nrPDB 149 2e-36 5LVV-A nrPDB 149 2e-36 Sequences not found previously or not previously below threshold: 6B85-J nrPDB 57 2e-08 5NNP-A nrPDB 50 2e-06 5G04-F nrPDB 49 6e-06 5G05-C nrPDB 48 8e-06 2GW1-A nrPDB 48 9e-06 6AHD-N nrPDB 47 1e-05 5FZQ-A nrPDB 43 3e-04 5KHR-J nrPDB 42 4e-04 6FO1-G nrPDB 42 4e-04 5DSE-A nrPDB 41 9e-04 5JJT-A nrPDB 40 0.002 6MFV-A nrPDB 38 0.011 2C2L-A nrPDB 37 0.018 5OJF-A nrPDB 37 0.021 6FRK-r nrPDB 36 0.039 4UZY-A nrPDB 36 0.043 5AEM-A nrPDB 36 0.052 5G04-X nrPDB 36 0.053 3Q15-A nrPDB 36 0.056 3ZFW-A nrPDB 35 0.059 5JZ6-A nrPDB 35 0.066 3ZN3-A nrPDB 35 0.082 4JA9-A nrPDB 34 0.10 4I9E-A nrPDB 34 0.11 5OJ8-A nrPDB 34 0.12 3NF1-A nrPDB 34 0.14 6FUZ-A nrPDB 34 0.15 5O09-1C nrPDB 34 0.18 6AF0-A nrPDB 33 0.25 4JHR-A nrPDB 33 0.28 5WQL-B nrPDB 33 0.31 4CJ9-A nrPDB 32 0.38 6CR2-A nrPDB 32 0.48 4ABN-A nrPDB 32 0.57 5MGX-E nrPDB 32 0.58 5LJ5-S nrPDB 32 0.77 3LY9-A nrPDB 32 0.80 4CGU-A nrPDB 31 0.88 6C95-A nrPDB 31 0.96 1A17-A nrPDB 31 0.97 5O6D-A nrPDB 31 1.6 3JCM-G nrPDB 31 1.7 6ICZ-I nrPDB 30 2.0 2CJQ-A nrPDB 30 2.3 3J98-H nrPDB 30 2.9 3OKY-A nrPDB 29 3.3 3AL9-A nrPDB 29 3.3 4KVO-A nrPDB 29 5.0 >5UDI-A nrPDB Length = 479 Score = 758 bits (1958), Expect = 0.0, Method: Composition-based stats. Identities = 476/478 (99%), Positives = 476/478 (99%) Query: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY Sbjct: 2 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 61 Query: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK Sbjct: 62 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 121 Query: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG Sbjct: 122 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 181 Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 240 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI Sbjct: 182 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 241 Query: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 300 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI Sbjct: 242 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 301 Query: 301 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE Sbjct: 302 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 361 Query: 361 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 420 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN Sbjct: 362 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 421 Query: 421 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP 478 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEA EYYERA RLAADFENSVRQGP Sbjct: 422 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEAEEYYERAERLAADFENSVRQGP 479 >4HOQ-A nrPDB Length = 482 Score = 669 bits (1727), Expect = 0.0, Method: Composition-based stats. Identities = 266/467 (56%), Positives = 351/467 (75%), Gaps = 3/467 (0%) Query: 7 DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 66 +K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKG Sbjct: 6 KDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKG 65 Query: 67 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 126 QN++AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CK Sbjct: 66 QNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCK 125 Query: 127 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 186 KLS+P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ Y Sbjct: 126 KLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVY 185 Query: 187 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN 246 RLD + K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L Sbjct: 186 RLDDSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQ 244 Query: 247 MSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEAT 306 +SSQ YV RYAAKFYRRK S +KALELLKKAL+ TPTS LHHQ+GLCY+AQMIQIK+AT Sbjct: 245 ISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKAT 304 Query: 307 KGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKL 366 +P+G+++ K+D++I SAIFHF++A+E+ F A+ DLA MY E G + AE+ F+K Sbjct: 305 HNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKA 364 Query: 367 LCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLV 426 L ++ + ++ IH+HYGRFQEF +KS+ AI HYL+A+K++ S R K ++LKKL Sbjct: 365 LRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLS 424 Query: 427 LRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 ++L ALD++SLS LGFVYKLEG +A EYYE+A ++ D EN+ Sbjct: 425 TKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI--DPENA 469 >4G1T-A nrPDB Length = 472 Score = 601 bits (1549), Expect = e-172, Method: Composition-based stats. Identities = 216/472 (45%), Positives = 303/472 (64%), Gaps = 21/472 (4%) Query: 1 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 60 MS N + + ++ SL QL+CHFTW L ++ + D E++V + EF + ++ + NLLAY Sbjct: 1 MSEN-NKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAY 59 Query: 61 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 120 +KHLKGQNE AL+ L++AE L+Q+EH +QA +RSLVTWGN+AW+YYHMGRL++ Q Y+DK Sbjct: 60 LKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDK 119 Query: 121 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 180 V+++C+K S+P YR+E PE+DCEEGW LKCGG ERAK CFEK LE P+NPE ++G Sbjct: 120 VKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSG 177 Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQD----EGQEAEG 236 AI++YRLD + + ++ PLRQA+RLNPDN Y+KVLLALKL +E EG Sbjct: 178 LAIASYRLDNWPPSQN-----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEG 232 Query: 237 EKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK 296 EK +EEAL T V R AAKFYRRK DKA+ELLKKAL+ P + LH QIG CY+ Sbjct: 233 EKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYR 292 Query: 297 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPT-FEVAHLDLARMYIEAGN 355 A++ Q+ + G + KL ++I A+ H + A E F V + LA ++ A Sbjct: 293 AKVFQVMNLRENGMYG--KRKLLELIGHAVAHLKKADEANDNLFRVCSI-LASLHALADQ 349 Query: 356 HRKAEENFQKLLC--MKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASL 413 + +AE FQK + PV + Q +H YG FQ +Q K + AI H+++ +KI Q S Sbjct: 350 YEEAEYYFQKEFSKELTPVAK---QLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSR 406 Query: 414 TRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALR 465 ++K + L+K+ +L + D E+L +L F+ +L M +A E ER L Sbjct: 407 EKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLE 458 >4HOU-A nrPDB Length = 273 Score = 474 bits (1220), Expect = e-134, Method: Composition-based stats. Identities = 273/273 (100%), Positives = 273/273 (100%) Query: 7 DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 66 DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG Sbjct: 1 DHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 60 Query: 67 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 126 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK Sbjct: 61 QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 120 Query: 127 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 186 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY Sbjct: 121 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 180 Query: 187 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN 246 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN Sbjct: 181 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN 240 Query: 247 MSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 279 MSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ Sbjct: 241 MSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 273 >1W3B-A nrPDB Length = 388 Score = 258 bits (658), Expect = 5e-69, Method: Composition-based stats. Identities = 64/288 (22%), Positives = 111/288 (38%), Gaps = 48/288 (16%) Query: 202 SLLPLRQAVRLNPD--NGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRY-AA 258 ++ R A+RL PD +GYI + AL + E + Y+ N Y R Sbjct: 86 AIEHYRHALRLKPDFIDGYINLAAALVAAGD-MEGAVQAYVSALQYN--PDLYCVRSDLG 142 Query: 259 KFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKL 318 + G +++A KA++ P + +G + AQ Sbjct: 143 NLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQ-------------------- 182 Query: 319 DKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEE 375 I AI HFE AV P F A+++L + EA +A + + L + P VV Sbjct: 183 -GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHG 241 Query: 376 TMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIE----------QASLTRDKSINSLKKL 425 + +++ G AI Y +AI+++ +L S+ + Sbjct: 242 NLACVYYEQGLIDL--------AIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDC 293 Query: 426 VLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 LR +SL+ L + + +GN+ EA+ Y +AL + +F + Sbjct: 294 YNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 341 Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats. Identities = 39/198 (19%), Positives = 73/198 (36%), Gaps = 33/198 (16%) Query: 157 YERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD- 215 ++RA A + + L + P + A Y + ++ R+A+ L P Sbjct: 219 FDRAVAAYLRALSLSPNHAVVHGNLACVYY--------EQGLIDLAIDTYRRAIELQPHF 270 Query: 216 -NGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELL 274 + Y + ALK + EA E AL + A R +G++++A+ L Sbjct: 271 PDAYCNLANALKEKGSVAEA--EDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLY 328 Query: 275 KKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVE 334 +KAL+ P H + + Q ++ A+ H++ A+ Sbjct: 329 RKALEVFPEFAAAHSNLASVLQQQ---------------------GKLQEALMHYKEAIR 367 Query: 335 KKPTFEVAHLDLARMYIE 352 PTF A+ ++ E Sbjct: 368 ISPTFADAYSNMGNTLKE 385 Score = 83.7 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 61/293 (20%), Positives = 112/293 (38%), Gaps = 35/293 (11%) Query: 111 LAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEG--WALLKCGGKNYERAKACFEKVL 168 LA A +E + + +Y P++ C LLK G+ E AKAC+ K + Sbjct: 107 LAAALVAAGDMEGAVQAYVSALQYN---PDLYCVRSDLGNLLKALGR-LEEAKACYLKAI 162 Query: 169 EVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD--NGYIKVLLALK 226 E P +A++ L A ++ +AV L+P+ + YI + LK Sbjct: 163 ETQPN-------FAVAWSNLGCVFNAQGEIW-LAIHHFEKAVTLDPNFLDAYINLGNVLK 214 Query: 227 LQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVL 286 A Y+ AL+ + V A Y +G +D A++ ++A++ P Sbjct: 215 EARIFDRA-VAAYLR-ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPD 272 Query: 287 LHHQIGL-------------CYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAV 333 + + CY + N ++ I A+ + A+ Sbjct: 273 AYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKAL 332 Query: 334 EKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGR 386 E P F AH +LA + + G ++A ++++ + + P T D + + G Sbjct: 333 EVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP----TFADAYSNMGN 381 Score = 74.0 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 50/278 (17%), Positives = 96/278 (34%), Gaps = 60/278 (21%) Query: 235 EGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLC 294 E++ + T V + + + +D++ A+++ P + +G Sbjct: 17 AAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNV 76 Query: 295 YKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAG 354 YK RGQ ++ AI H+ A+ KP F +++LA + AG Sbjct: 77 YKE-------------RGQ--------LQEAIEHYRHALRLKPDFIDGYINLAAALVAAG 115 Query: 355 NHRKAEENFQKLLCMKP---VVEETMQDIHFHYGRFQE---------------------- 389 + A + + L P V + ++ GR +E Sbjct: 116 DMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNL 175 Query: 390 ---FQKKSDV-NAIIHYLKAIKIE----------QASLTRDKSINSLKKLVLRKLRRKAL 435 F + ++ AI H+ KA+ ++ L + + LR L Sbjct: 176 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPN 235 Query: 436 DLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 L VY +G ++ A++ Y RA+ L F ++ Sbjct: 236 HAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDA 273 >5A01-A nrPDB Length = 710 Score = 149 bits (377), Expect = 2e-36, Method: Composition-based stats. Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 13/137 (9%) Query: 248 SSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ------MIQ 301 S+ A R +G +++A L KAL+ P H + + Q ++ Sbjct: 4 SNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMH 63 Query: 302 IKEATKGQP-------RGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAG 354 KEA + QP N K + + A+ + A++ P F AH +LA ++ ++G Sbjct: 64 YKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSG 123 Query: 355 NHRKAEENFQKLLCMKP 371 N +A ++++ L +KP Sbjct: 124 NIPEAIQSYRTALKLKP 140 Score = 81.4 bits (199), Expect = 8e-16, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 63/150 (42%), Gaps = 21/150 (14%) Query: 337 PTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEETMQDIHFHYGRFQEFQKK 393 + +LA + E G +A + K L + P + + G+ +E Sbjct: 4 SNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKE---- 59 Query: 394 SDVNAIIHYLKAIKIE----------QASLTRDKSINSLKKLVLRKLRRKALDLESLSLL 443 A++HY +AI+I+ +L + ++ + R ++ ++ S L Sbjct: 60 ----ALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNL 115 Query: 444 GFVYKLEGNMNEALEYYERALRLAADFENS 473 ++K GN+ EA++ Y AL+L DF ++ Sbjct: 116 ASIHKDSGNIPEAIQSYRTALKLKPDFPDA 145 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 51/263 (19%), Positives = 95/263 (36%), Gaps = 26/263 (9%) Query: 179 AGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEK 238 + +A S L K + + L L+ A+ + PD LA LQ +G+ E Sbjct: 4 SNHADSLNNLANIKREQGYIEEATRLYLK-ALEVFPDFAAAHSNLASVLQQQGKLKEALM 62 Query: 239 YIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ 298 + +EA+ + + + V AL+ +A+Q P H + + Sbjct: 63 HYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIH--- 119 Query: 299 MIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRK 358 K I AI + +A++ KP F A+ +LA + Sbjct: 120 ------------------KDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTD 161 Query: 359 AEENFQKLLCM--KPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRD 416 + +KL+ + + + + + +H H+ AI + +E+ + Sbjct: 162 YDIRMKKLVSIVTEQLEKNRLPSVHPHHSMLYPLTHDCR-KAIAARHANLCLEKVHVLHK 220 Query: 417 KSINSLKKLVLR-KLRRKALDLE 438 K N LKKL + +LR L + Sbjct: 221 KPYNFLKKLPTKGRLRIGYLSSD 243 Score = 51.7 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 433 KALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 + +SL+ L + + +G + EA Y +AL + DF + Sbjct: 3 CSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAA 43 >5LVV-A nrPDB Length = 749 Score = 149 bits (376), Expect = 2e-36, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 13/133 (9%) Query: 252 YVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ------MIQIKEA 305 A R +G++++A+ L +KAL+ P H + + Q ++ KEA Sbjct: 31 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA 90 Query: 306 TKGQP-------RGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRK 358 + P N K + ++ A+ + A++ P F AH +LA ++ ++GN + Sbjct: 91 IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPE 150 Query: 359 AEENFQKLLCMKP 371 A +++ L +KP Sbjct: 151 AIASYRTALKLKP 163 Score = 84.1 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 21/149 (14%) Query: 338 TFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP---VVEETMQDIHFHYGRFQEFQKKS 394 T + +LA + E GN +A ++K L + P + + G+ QE Sbjct: 28 THADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE----- 82 Query: 395 DVNAIIHYLKAIKIE----------QASLTRDKSINSLKKLVLRKLRRKALDLESLSLLG 444 A++HY +AI+I +L + + + R ++ ++ S L Sbjct: 83 ---ALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLA 139 Query: 445 FVYKLEGNMNEALEYYERALRLAADFENS 473 ++K GN+ EA+ Y AL+L DF ++ Sbjct: 140 SIHKDSGNIPEAIASYRTALKLKPDFPDA 168 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 76/209 (36%), Gaps = 24/209 (11%) Query: 181 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 240 +A S L K N + ++ R+A+ + P+ LA LQ +G+ E + Sbjct: 29 HADSLNNLANIKREQGNIEE-AVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHY 87 Query: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 300 +EA+ + + + V AL+ +A+Q P H + + Sbjct: 88 KEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIH----- 142 Query: 301 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360 K I AI + +A++ KP F A+ +LA + + Sbjct: 143 ----------------KDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYD 186 Query: 361 ENFQKLLCM--KPVVEETMQDIHFHYGRF 387 E +KL+ + + + + +H H+ Sbjct: 187 ERMKKLVSIVADQLEKNRLPSVHPHHSML 215 Score = 57.5 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 26/57 (45%), Gaps = 3/57 (5%) Query: 420 NSLKKLVLRKLRRK---ALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 +S + + +SL+ L + + +GN+ EA+ Y +AL + +F + Sbjct: 10 SSAQSTSKTSVTLSLGGGTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 66 Score = 34.7 bits (78), Expect = 0.093, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 70/174 (40%), Gaps = 31/174 (17%) Query: 56 NLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQ 115 N LA +K +G EEA++ ++A + E +N+ S++ G+L EA Sbjct: 34 NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ---------QQGKLQEAL 84 Query: 116 TYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENP 175 + + I ++ + G L + ++ + A C+ + ++++P Sbjct: 85 MHYKEAIRISPTFADAYS----------NMGNTLKEM--QDVQGALQCYTRAIQINPAFA 132 Query: 176 ESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD--NGYIKVLLALKL 227 ++ + A + P ++ R A++L PD + Y + L++ Sbjct: 133 DAHSNLA--------SIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQI 178 >6B85-J nrPDB Length = 223 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 38/185 (20%), Positives = 70/185 (37%), Gaps = 26/185 (14%) Query: 210 VRLNPDNGYIKVLLALKLQDEGQ---------EAEGEKYIEEALANMSSQTYVFRYAAKF 260 + NPD I LL+++L + E+ E ++S+ YV Sbjct: 33 ITTNPDTSQIATLLSMQLLLIALMLVVIALLLSRQTEQVAESIRRDVSALAYVMLGLL-- 90 Query: 261 YRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK------AQMIQIKEATKGQPR--- 311 + A E KKA++ P L +G + K+A + +P Sbjct: 91 LSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDAS 150 Query: 312 -----GQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKL 366 G+ EKL ++ A ++ A+E P A +L ++ + G +A E ++K Sbjct: 151 AWKELGKVLEKLGRL-DEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKA 209 Query: 367 LCMKP 371 + + P Sbjct: 210 IELDP 214 Score = 54.8 bits (130), Expect = 7e-08, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 62/185 (33%), Gaps = 35/185 (18%) Query: 291 IGLCYKAQMIQIKEATKGQPRG------QNREKLDKMIRSAIFHFESAVEKKPTFEVAHL 344 I L Q Q+ E+ + L + A ++ A+E P +A L Sbjct: 60 IALLLSRQTEQVAESIRRDVSALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWL 119 Query: 345 DLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLK 404 L + + +A E ++K + +KP G+ Sbjct: 120 LLGSVLEKLKRLDEAAEAYKKAIELKP----NDASAWKELGKV----------------- 158 Query: 405 AIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL 464 L + ++ + + + D E+ LG V + G ++EA E Y++A+ Sbjct: 159 --------LEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAI 210 Query: 465 RLAAD 469 L + Sbjct: 211 ELDPN 215 Score = 52.9 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 54/137 (39%), Gaps = 21/137 (15%) Query: 207 RQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGS 266 ++A+ L+P++ +LL L+ + E + ++A+ + ++ K + G Sbjct: 105 KKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGR 164 Query: 267 VDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAI 326 +D+A E KKA++ P ++G + +LD+ A Sbjct: 165 LDEAAEAYKKAIELDPEDAEAWKELGKVL-----------------EKLGRLDE----AA 203 Query: 327 FHFESAVEKKPTFEVAH 343 ++ A+E P H Sbjct: 204 EAYKKAIELDPNDLEHH 220 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 54/131 (41%), Gaps = 8/131 (6%) Query: 160 AKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYI 219 A ++K +E+DP + A+ L G L + ++A+ L P++ Sbjct: 100 AAEAYKKAIELDPNDA--------LAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASA 151 Query: 220 KVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 279 L L+ G+ E + ++A+ ++ K + G +D+A E KKA++ Sbjct: 152 WKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIE 211 Query: 280 ETPTSVLLHHQ 290 P + HH Sbjct: 212 LDPNDLEHHHH 222 >5NNP-A nrPDB Length = 745 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 44/256 (17%), Positives = 83/256 (32%), Gaps = 26/256 (10%) Query: 229 DEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLH 288 ++ Q G K E+ L A +G ++A L K+AL S + Sbjct: 22 EDKQYKRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEALTIDMKSYICW 81 Query: 289 HQIGLCYKAQ------MIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVE-------K 335 H G+ Y+ + K A K +P ++ +++ + + V+ Sbjct: 82 HVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQIQMRDYAGYVQSRLNMLKA 141 Query: 336 KPTFEVAHLDLARMYIEAGNHRKAEEN---FQKLLCMKPVVEETMQDIHFHYGRFQEFQK 392 +P LA Y GN KAE ++K L P + Y ++ Sbjct: 142 RPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDLEHSEALLYKNTIIAER 201 Query: 393 KSDVNAIIHY----------LKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSL 442 A+ H L +++ + L++ + K L R ++ Sbjct: 202 GDIERALQHLETDCKHCLDRLAVMELRASYLSKLARKDEAAKAYRALLDRNPEHMDYYKG 261 Query: 443 LGFVYKLEGNMNEALE 458 L + + EA + Sbjct: 262 LISALDISADDEEAQK 277 Score = 35.5 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 60/304 (19%), Positives = 101/304 (33%), Gaps = 43/304 (14%) Query: 98 WGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNY 157 W A Y+ G L +A+ L E K L+ P P+ D E ALL Sbjct: 149 WTALAIAYHLEGNLEKAEHILTTYE---KSLTTPP------PKTDLEHSEALLYKNTIIA 199 Query: 158 ERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD-- 215 ER E+ L+ + + ++ L L+ K + R + NP+ Sbjct: 200 ERGDI--ERALQHLETDCKHCLD-RLAVMELRASYLSKLARKDEAAKAYRALLDRNPEHM 256 Query: 216 NGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQT-----------YVFRYAAKFYRRK 264 + Y ++ AL + + +EA+ Y E A S FR AK Y Sbjct: 257 DYYKGLISALDISADDEEAQKAVYDEYAAKYPRSDAAKRLPLNFLSGERFRTTAKAYLTL 316 Query: 265 GSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEAT--KGQPRGQNREK----- 317 DK + L+ + + + + + A Q G + Sbjct: 317 -MFDKGVPSTFANLKHLYSDSFKKETLASLAEEYLNEYVNARPSDNQADGDGSKGKGAAL 375 Query: 318 ----------LDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLL 367 + + + A+ + E A+E P H+ AR++ G+ KA E Sbjct: 376 YYLAQHYNYYMSRDLTRALEYVEKAIELDPKNVDFHMTKARIFKHQGDLAKAAETMDYAR 435 Query: 368 CMKP 371 + P Sbjct: 436 SLDP 439 >5G04-F nrPDB Length = 824 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 47/149 (31%), Gaps = 33/149 (22%) Query: 268 DKALELLKKAL-QETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAI 326 D AL +L K L S G C+ Q AI Sbjct: 549 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREH---------------------DIAI 587 Query: 327 FHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEET---MQDIHFH 383 F+ A++ P + A+ L ++ KA F+ + + P + I++ Sbjct: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647 Query: 384 YGRFQEFQKKSDVNAIIHYLKAIKIEQAS 412 +F + H+ KA+ I S Sbjct: 648 QEKFSLAEM--------HFQKALDINPQS 668 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 57/302 (18%), Positives = 103/302 (34%), Gaps = 60/302 (19%) Query: 100 NFAWMYYHMGRLA-EAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLK------- 151 N W+ +GR E Y+ + E I ++ YR+E EI W L K Sbjct: 497 NTGWVLCQIGRAYFELSEYM-QAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVL 555 Query: 152 ---------------CGGKN-------YERAKACFEKVLEVDPENPESSAGYAISAYRLD 189 C N ++ A F++ ++VDP + YA Y L Sbjct: 556 SKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDP-----NYAYA---YTLL 607 Query: 190 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 249 G + +L R A+R+NP + L + + + + E + ++AL Sbjct: 608 GHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667 Query: 250 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQ 309 + + + +KAL+ L KA+ P + L A Sbjct: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA------------ 715 Query: 310 PRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369 ++ +SA+ E + P + + + ++Y + G A NF + + Sbjct: 716 ---------NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766 Query: 370 KP 371 P Sbjct: 767 DP 768 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 62/163 (38%), Gaps = 14/163 (8%) Query: 158 ERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNG 217 ++A ACF + V+P + + G + Y+ + F LA + ++A+ +NP + Sbjct: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH--------FQKALDINPQSS 669 Query: 218 YIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKA 277 + + + + + + +A+ + A AL+ L++ Sbjct: 670 VLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729 Query: 278 LQETPTSVLLHHQIGLCYKA------QMIQIKEATKGQPRGQN 314 Q P L++ IG YK ++ A P+G N Sbjct: 730 KQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGAN 772 >5G05-C nrPDB Length = 597 Score = 48.2 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 40/235 (17%), Positives = 83/235 (35%), Gaps = 29/235 (12%) Query: 256 YAAKFYRRKGSVDKALELLKKALQE-TPTSVLLHHQIGLCY-KAQMIQIKEATKGQPRGQ 313 + A Y +++AL+ + + S + QI + Y + I + + R Q Sbjct: 233 FLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQ 292 Query: 314 NREKLDKMIRSAIFHFESAVEKKPTFE---VAHLD---------LARMYIEAGNHRKAEE 361 + +++ M + + +++ + ++ + +D + Y H KA Sbjct: 293 DPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAAL 352 Query: 362 NFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR---DKS 418 FQ+ L + P + Y + K+ AI Y AI++ + Sbjct: 353 YFQRALKLNPRYLGAWTLMGHEY-----MEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 Query: 419 INSLKKL-------VLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRL 466 + K+ R + + D L LG Y+ + EA + Y RA + Sbjct: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV 462 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 24/149 (16%), Positives = 54/149 (36%), Gaps = 17/149 (11%) Query: 325 AIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHY 384 A +F+ A++ P + A + Y+E N A + ++ +E +D Y Sbjct: 350 AALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHA------IEVNKRDYRAWY 403 Query: 385 GRFQEFQ-KKSDVNAIIHYLKAIKIEQAS----------LTRDKSINSLKKLVLRKLRRK 433 G Q ++ K + +Y +A ++ + + KK R Sbjct: 404 GLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVG 463 Query: 434 ALDLESLSLLGFVYKLEGNMNEALEYYER 462 ++ +L L +++ +A + Y + Sbjct: 464 DVEKMALVKLAKLHEQLTESEQAAQCYIK 492 >2GW1-A nrPDB Length = 514 Score = 47.8 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 45/219 (20%), Positives = 83/219 (37%), Gaps = 20/219 (9%) Query: 164 FEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLL 223 F+K L++D N + L + A K+ +A L+P+N + + L Sbjct: 293 FDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFD--------KAKELDPENIFPYIQL 344 Query: 224 ALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPT 283 A E + + E EA V + A+ K DKAL+ A++ Sbjct: 345 ACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENK 404 Query: 284 SVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAH 343 ++ I A ++ P +N + ++ E A + P E A Sbjct: 405 LDGIYVGI-----APLVGKATLLTRNPTVENFIEATNLL-------EKASKLDPRSEQAK 452 Query: 344 LDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHF 382 + LA+M ++ + +A F++ + +EE +Q I F Sbjct: 453 IGLAQMKLQQEDIDEAITLFEESADLARTMEEKLQAITF 491 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 59/324 (18%), Positives = 129/324 (39%), Gaps = 36/324 (11%) Query: 155 KNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNP 214 +++ +A FE+ L+ + E+ + AIS FK KN + +++A+ L P Sbjct: 210 ESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIFKF-LKNDPLGAHEDIKKAIELFP 268 Query: 215 D-NGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALEL 273 N YI +AL + D E Y ++AL S+ + V+ + + + D+A + Sbjct: 269 RVNSYI--YMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKD 326 Query: 274 LKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAV 333 KA + P ++ + Q+ + +E + + + A F A Sbjct: 327 FDKAKELDPENIFPYIQLAC------LAYRE--------NKFDDCETLFSEAKRKFPEAP 372 Query: 334 EKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKK 393 E P F A + + + KA + + + ++ ++ I G+ + Sbjct: 373 EV-PNF------FAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTR- 424 Query: 394 SDVNAIIHYLKAIKIEQASLTRDKSINSLK-KLVLRKLRRKALDLESLSLL---GFVYKL 449 + ++++A + + + D K L KL+++ +D E+++L + + Sbjct: 425 --NPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDID-EAITLFEESADLART 481 Query: 450 EGNMNEALEYYERA---LRLAADF 470 +A+ + E A R+ +D Sbjct: 482 MEEKLQAITFAEAAKVQQRIRSDP 505 Score = 29.4 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 28/71 (39%), Gaps = 1/71 (1%) Query: 400 IHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEY 459 Y A+K + R+K + K L K D S L Y G++ + +E Sbjct: 3 DKYALALKDKGNQFFRNKKYDDAIKYYNWALELKE-DPVFYSNLSACYVSVGDLKKVVEM 61 Query: 460 YERALRLAADF 470 +AL L D+ Sbjct: 62 STKALELKPDY 72 >6AHD-N nrPDB Length = 941 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 29/219 (13%), Positives = 67/219 (30%), Gaps = 19/219 (8%) Query: 263 RKGSVDKALELLKKALQETPTSVLLH-------------HQIGLCYKAQMIQIKEATKGQ 309 +++ A + ALQ P+ + + + + +A Sbjct: 552 AHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLW 611 Query: 310 PRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369 G + L + +A A + P E L ++ E + +A K Sbjct: 612 LMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSS 671 Query: 370 KPVVEETMQDIHFH--YGRFQEFQKKSDVNAIIHYLKAIKI---EQASLTRDKSINSLKK 424 P M+ + + Q + A+ HY K+ + + + + ++ Sbjct: 672 APTARVFMKSVKLEWVQDNIRAAQDLCE-EALRHYEDFPKLWMMKGQIEEQKEMMEKARE 730 Query: 425 LVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERA 463 + L++ LL + + G + A E++ Sbjct: 731 AYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKS 769 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 48/275 (17%), Positives = 105/275 (38%), Gaps = 41/275 (14%) Query: 209 AVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVD 268 A + NP++ I L A+KL+ E E E + + + + VF + K + ++ Sbjct: 634 AFQANPNSEEI-WLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIR 692 Query: 269 KALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFH 328 A +L ++AL+ L G + + +M+ A Sbjct: 693 AAQDLCEEALRHYEDFPKLWMMKGQIEEQK---------------------EMMEKAREA 731 Query: 329 FESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEET-MQDIHFHY--- 384 + ++K P L L+R+ + G +A +K P ++ + Y Sbjct: 732 YNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAG 791 Query: 385 ------GRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLE 438 + ++ + I+ + +AI +E R KS+++LKK D Sbjct: 792 LKNIANTLMAKALQECPNSGIL-WSEAIFLEARPQRRTKSVDALKKCEH--------DPH 842 Query: 439 SLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 L + ++ + + +A E++ R +++ +D ++ Sbjct: 843 VLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDA 877 Score = 32.1 bits (71), Expect = 0.61, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 63/173 (36%), Gaps = 9/173 (5%) Query: 208 QAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSV 267 Q ++ P + + +LL+ + GQ +E++ ++ + + R G Sbjct: 734 QGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLK 793 Query: 268 DKALELLKKALQETPTSVLLHHQ---IGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRS 324 + A L+ KALQE P S +L + + + + + K + + K+ S Sbjct: 794 NIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWS 853 Query: 325 ------AIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP 371 A F V+ A + ++ G + EE ++ +P Sbjct: 854 QRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEP 906 Score = 31.3 bits (69), Expect = 0.85, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 51/125 (40%), Gaps = 12/125 (9%) Query: 208 QAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSV 267 QAVR P + I + A D + ++ + +AL ++ + +++ A Sbjct: 364 QAVRHLPQSVRIYIRAAELETDIRAK---KRVLRKALEHVPNSVRLWKAAV----ELEEP 416 Query: 268 DKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIF 327 + A +L +A++ PTSV L + A++ + A K + + D+ I Sbjct: 417 EDARIMLSRAVECCPTSVELWLAL-----ARLETYENARKVLNKARENIPTDRHIWITAA 471 Query: 328 HFESA 332 E A Sbjct: 472 KLEEA 476 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 26/135 (19%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 156 NYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPD 215 RA+A EK +P+NP G + + RL+ K + + +A++ P+ Sbjct: 758 QLTRARAILEKSRLKNPKNP----GLWLESVRLE----YRAGLKNIANTLMAKALQECPN 809 Query: 216 NGYIKVLLALKLQDEGQEAEGEKYIE--EALANMSSQTYVFRYAAKFYRRKGSVDKALEL 273 +G L + EA ++ + +AL +V AK + + + KA E Sbjct: 810 SG------ILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREW 863 Query: 274 LKKALQETPTSVLLH 288 + ++ Sbjct: 864 FHRTVKIDSDLGDAW 878 >5FZQ-A nrPDB Length = 131 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 41/116 (35%), Gaps = 21/116 (18%) Query: 254 FRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQ 313 A ++G ++A++ ++KA+ P ++ + + G+ Sbjct: 8 LSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQE-------------GK 54 Query: 314 NREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369 E AI + AV P +LA + + G +A + +K + + Sbjct: 55 AEE--------AIKYMRKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 44/130 (33%), Gaps = 5/130 (3%) Query: 304 EATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENF 363 + K N + AI + AV P +LA + + G +A + Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 364 QKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLK 423 +K + + P +T+ ++ Q+ AI + KA+ + + + Sbjct: 63 RKAVSLDPNNIKTLSNL-----AVLLAQEGKAEEAIKYMRKAVSLIDKAAKGSTLHKNAA 117 Query: 424 KLVLRKLRRK 433 +L RK Sbjct: 118 ARRKSRLMRK 127 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 44/123 (35%), Gaps = 29/123 (23%) Query: 344 LDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYL 403 +LA + + G +A + +K + + P + + Sbjct: 9 SNLANLLAQEGKAEEAIKYMRKAVSLDP-----------------------------NNI 39 Query: 404 KAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERA 463 K + L ++ K + + + ++++LS L + EG EA++Y +A Sbjct: 40 KTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKA 99 Query: 464 LRL 466 + L Sbjct: 100 VSL 102 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 53/112 (47%), Gaps = 3/112 (2%) Query: 193 LATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTY 252 LA + ++ +R+AV L+P+N LA L EG+ E KY+ +A++ + Sbjct: 15 LAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIK 74 Query: 253 VFRYAAKFYRRKGSVDKALELLKKALQETPTSV---LLHHQIGLCYKAQMIQ 301 A ++G ++A++ ++KA+ + LH K+++++ Sbjct: 75 TLSNLAVLLAQEGKAEEAIKYMRKAVSLIDKAAKGSTLHKNAAARRKSRLMR 126 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 3/115 (2%) Query: 223 LALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETP 282 LA L EG+ E KY+ +A++ + A ++G ++A++ ++KA+ P Sbjct: 11 LANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDP 70 Query: 283 TSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKP 337 ++ + AQ + +EA K + + +DK + + H +A +K Sbjct: 71 NNIKTLSNLA-VLLAQEGKAEEAIKYMRKAVSL--IDKAAKGSTLHKNAAARRKS 122 Score = 36.7 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 27/60 (45%) Query: 410 QASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAAD 469 L ++ K + + + ++++LS L + EG EA++Y +A+ L + Sbjct: 12 ANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPN 71 >5KHR-J nrPDB Length = 620 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 44/267 (16%), Positives = 81/267 (30%), Gaps = 32/267 (11%) Query: 238 KYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKA 297 K + ++ L K + P++ + +G Y Sbjct: 252 KLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLM 311 Query: 298 QMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARM-------- 349 + + A + + EK A H + + A+ A++ Sbjct: 312 VGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPM 371 Query: 350 ------YIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYL 403 Y N + AE F + L + P M ++ FQ + K+ + L Sbjct: 372 LYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVV--AFQNGEWKTAEKWFLDAL 429 Query: 404 KAIKIEQASLTRD----------------KSINSLKKLVLRKLRRKALDLESLSLLGFVY 447 + IK +T D K + L + + S +G+++ Sbjct: 430 EKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIH 489 Query: 448 KLEGNMNEALEYYERALRLAADFENSV 474 L GN A++Y+ AL L D SV Sbjct: 490 SLMGNFENAVDYFHTALGLRRDDTFSV 516 >6FO1-G nrPDB Length = 665 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 54/358 (15%), Positives = 126/358 (35%), Gaps = 63/358 (17%) Query: 102 AWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAK 161 AW + R+ + LDK ++ + LS + +D ++ L + G K +++ K Sbjct: 92 AWAKLDVDRILDE---LDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGK 148 Query: 162 A-----CFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDN 216 C+ K ++ DP NP A + +RL F +A + Sbjct: 149 YDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCN----------------- 191 Query: 217 GYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKK 276 + AL ++ Y R AA+F +++A + ++ Sbjct: 192 -----------------------LAVALNRSYTKAYSRRGAARF--ALQKLEEAKKDYER 226 Query: 277 ALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKK 336 L+ P + +++ +A A+K + + + K E+ ++ Sbjct: 227 VLELEPNNFEATNELRKISQA------LASKENSYPKEADIVIKSTEGERKQIEA--QQN 278 Query: 337 PTFEVAHLDLARMYIEAGNHRKAEENFQKLLC---MKPVVEETMQDIHFHYGRFQEFQKK 393 ++ D + + G + +A E + + + ++ + +++E +K Sbjct: 279 KQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKD 338 Query: 394 SDVNAII--HYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKL 449 ++ Y KA + T +N K+ L + + ++++ L + K Sbjct: 339 CTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKE 396 >5DSE-A nrPDB Length = 837 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 78/454 (17%), Positives = 149/454 (32%), Gaps = 62/454 (13%) Query: 45 FLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWM 104 + + + +++LL +GQ E + L+ A EE W FA Sbjct: 350 LISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFH---------LWYQFALS 400 Query: 105 YYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNY--ERAKA 162 G+ A A L + C +L P+ A C G + E A+ Sbjct: 401 LMAAGKSARAVKVLKE----CIRLK---------PDDATIPLLAAKLCMGSLHWLEEAEK 447 Query: 163 CFEKVLEVDPENPESSAGYAIS---AYRLDGFKLA----TKNHKPFSLLPLRQAVRLNPD 215 + V++V + E A ++ Y L + + + +LL ++A L+P Sbjct: 448 FAKTVVDVGEKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPT 507 Query: 216 NGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLK 275 + LAL+L Q E Y+ +AL A + AL ++ Sbjct: 508 DHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIID 567 Query: 276 KALQETP-TSVLLHHQI-----------GLCYKAQMIQIKEATKGQPRGQNREKLDKMIR 323 AL E P +LL ++ L M+QI ++ + + ++ Sbjct: 568 MALSEYPENFILLFSKVKLQSLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLD 627 Query: 324 SAIFHFESAVEKK-PTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHF 382 I P F ++ + + E+ + V ++Q Sbjct: 628 RTIADRRQLNTITLPDFSDPET--GSVHATSVAASRVEQALSE-------VASSLQSSAP 678 Query: 383 HYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSL 442 G + + + +L A ++ + L + Sbjct: 679 KQGPLHPWMTLAQI-----WLHAAEV----YIGIGKPAEATACTQEAANLFPMSHNVLYM 729 Query: 443 LGFVYKLEGNMNEALEYYERALRLAADFENSVRQ 476 G + +L G+M+EA +YE AL ++ S+++ Sbjct: 730 RGQIAELRGSMDEARRWYEEALAISPTHVKSMQR 763 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 34/167 (20%), Positives = 53/167 (31%), Gaps = 25/167 (14%) Query: 204 LPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRR 263 PL + L I + A G+ AE +EA V + Sbjct: 681 GPLHPWMTL----AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAEL 736 Query: 264 KGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIR 323 +GS+D+A ++AL +PT V ++ L Q+ + A K Sbjct: 737 RGSMDEARRWYEEALAISPTHVKSMQRLALILH-QLGRYSLAEKI--------------- 780 Query: 324 SAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMK 370 AV+ T L + GN A E F L ++ Sbjct: 781 -----LRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 822 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 37/80 (46%) Query: 208 QAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSV 267 +A+ ++P + LAL L G+ + EK + +A+ S+ V+ + + +G+ Sbjct: 749 EALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGND 808 Query: 268 DKALELLKKALQETPTSVLL 287 A E AL+ +S + Sbjct: 809 AAATECFLTALELEASSPAV 828 >5JJT-A nrPDB Length = 479 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 17/118 (14%), Positives = 37/118 (31%), Gaps = 21/118 (17%) Query: 254 FRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQ 313 F+ A + A++L KA++ + + + Sbjct: 12 FKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTK---------------- 55 Query: 314 NREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP 371 + SAI A+E + + Y+ G + A ++FQ++ + P Sbjct: 56 -----LEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSP 108 >6MFV-A nrPDB Length = 653 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 42/258 (16%), Positives = 91/258 (35%), Gaps = 40/258 (15%) Query: 215 DNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFR-----YAAKFYRRKGSVDK 269 DN Y K+ +A+ E Q EK I+ F+ + A Y +++K Sbjct: 364 DNPYAKIEIAII---EVQRGLFEKAIKLLKEAEPYVDEFFKCEIYSWLADAYMELENLEK 420 Query: 270 ALELLKKALQETP--TSVLLHHQIGLCYKAQMIQIKEATKGQPRG-QNREKLDKMIRSAI 326 A LKK + + Y A+ + + + ++ K ++IR Sbjct: 421 AERYLKKTKEIVEKINDMYAWFS----YYAEKTKYEYYKENSREALKSALKELEIIR--- 473 Query: 327 FHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLC---------MKPVVEETM 377 + +K + H+ +Y+ GN+ K +Q+ L ++ + + Sbjct: 474 ---KIGDPEKEGLVLLHV--GDIYLHMGNYEKGISYYQEALKMAKAYGIKFLEHISYMEL 528 Query: 378 QDIHFHYGRFQEFQKKSDVNA-----IIHYLKAIKIEQ---ASLTRDKSINSLKKLVLRK 429 ++ +++ + S+ A I +Y +A S K++ +K Sbjct: 529 AKGYYQLKLYEKASEYSEKAANYFLMIRNYRRATDAMAYGSVSYIATKNLEKAEKFAKEM 588 Query: 430 LRRKALDLESLSLLGFVY 447 +R L+ G+++ Sbjct: 589 IRIAQSTDYPLAWAGYIF 606 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 41/241 (17%), Positives = 91/241 (37%), Gaps = 18/241 (7%) Query: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 300 + L + Y A ++G +KA++LLK+A +I + Sbjct: 356 QRLLMEVEDNPYAKIEIAIIEVQRGLFEKAIKLLKEAEPYVDEF--FKCEIYSWLADAYM 413 Query: 301 QIKEATKGQPRGQNREKLDKMIR--SAIFHFESAVEKKPTF-EVAHLDLARMYIEAGNHR 357 +++ K + + +++ + I A F + + K + E + L E R Sbjct: 414 ELENLEKAERYLKKTKEIVEKINDMYAWFSYYAEKTKYEYYKENSREALKSALKELEIIR 473 Query: 358 KAEENFQKLLCMKPVVEETMQDIHFHYGR--FQEFQKKSDVNAI-----IHYLKAIKIEQ 410 K + ++ L + V + + ++ G +QE K + I I Y++ K Sbjct: 474 KIGDPEKEGLVLLHVGDIYLHMGNYEKGISYYQEALKMAKAYGIKFLEHISYMELAKGYY 533 Query: 411 ASLTRDKSINSLKKLVLRKLR----RKALDLESLSLLGFVYKLEGNMNEALEYYERALRL 466 +K+ +K L R+A D + + ++ N+ +A ++ + +R+ Sbjct: 534 QLKLYEKASEYSEKAANYFLMIRNYRRATDAMAYGSVSYIA--TKNLEKAEKFAKEMIRI 591 Query: 467 A 467 A Sbjct: 592 A 592 >2C2L-A nrPDB Length = 281 Score = 37.1 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 40/102 (39%), Gaps = 5/102 (4%) Query: 313 QNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPV 372 NR + + A + A+ + P V + + A Y++ +A + ++ L + Sbjct: 11 GNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALEL--- 67 Query: 373 VEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLT 414 + HF G+ Q + +S AI + +A + + Sbjct: 68 -DGQSVKAHFFLGQCQL-EMESYDEAIANLQRAYSLAKEQRL 107 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 33/101 (32%), Gaps = 21/101 (20%) Query: 269 KALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFH 328 +A +A+ P + + LCY K+ + A+ Sbjct: 22 EAAACYGRAITRNPLVAVYYTNRALCY--------------------LKMQQP-EQALAD 60 Query: 329 FESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369 A+E AH L + +E ++ +A N Q+ + Sbjct: 61 CRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 101 Score = 29.4 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 24/140 (17%), Positives = 47/140 (33%), Gaps = 10/140 (7%) Query: 261 YRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDK 320 Y + ++AL ++AL+ SV H +G C + +M EA R + K + Sbjct: 48 YLKMQQPEQALADCRRALELDGQSVKAHFFLGQC-QLEMESYDEAIANLQRAYSLAKEQR 106 Query: 321 MIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE-ENFQKLLCMKPVVEETMQD 379 + + +A E H+++E ++ L E + Sbjct: 107 LNFG--------DDIPSALRIAKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEEC 158 Query: 380 IHFHYGRFQEFQKKSDVNAI 399 H G + ++ I Sbjct: 159 QRNHEGHEDDGHIRAQQACI 178 >5OJF-A nrPDB Length = 314 Score = 36.7 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 40/261 (15%), Positives = 83/261 (31%), Gaps = 45/261 (17%) Query: 213 NPDNGYIKVLLALKLQDEGQEAEGEKYIEEALA--------NMSSQTYVFRYAAKFYRRK 264 +PD + +LAL +D+ + + + +ALA + + A Y ++ Sbjct: 66 HPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 125 Query: 265 GSVDKALELLKKALQET--------PTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNRE 316 G +A L K+AL+ P + L + Q E Sbjct: 126 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQ--------------GKAE 171 Query: 317 KLDKMIRSAIFHF-ESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEE 375 +++ R A+ + P +LA Y++ G ++ AE ++++L E Sbjct: 172 EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR---AHE 228 Query: 376 TMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKAL 435 +G + I + + + + Sbjct: 229 K------EFGSVN-----GENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPT 277 Query: 436 DLESLSLLGFVYKLEGNMNEA 456 +L LG +Y+ +G + A Sbjct: 278 VNTTLRSLGALYRRQGKLEAA 298 Score = 34.7 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 40/243 (16%), Positives = 78/243 (32%), Gaps = 83/243 (34%) Query: 245 ANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQET--------PTSVLLHHQIGLCYK 296 + ++ Y +G + A+ L K+AL++ P + + + L Y+ Sbjct: 22 YEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR 81 Query: 297 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKK-PTFEVAHLDLARMYIEAGN 355 Q + K+A ++ A+ E + K P +LA +Y + G Sbjct: 82 DQN-KYKDAAH-------------LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGK 127 Query: 356 HRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR 415 +++AE P+ + +A++I + L + Sbjct: 128 YKEAE----------PLCK-----------------------------RALEIREKVLGK 148 Query: 416 DKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVR 475 + LS L + + +G E YY RAL + + R Sbjct: 149 ----------------FHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY-----ATR 187 Query: 476 QGP 478 GP Sbjct: 188 LGP 190 >6FRK-r nrPDB Length = 605 Score = 35.9 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 62/150 (41%), Gaps = 13/150 (8%) Query: 152 CGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVR 211 C K + +A E + E ++PE++A ++ +L K++ N L+ LR Sbjct: 349 CREKQHTKA---IELLQEFSDQHPENAAEIKLTMAQL---KISQGNISKACLI-LRSIEE 401 Query: 212 LNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALA------NMSSQTYVFRYAAKFYRRKG 265 L G + L+ + +E ++ E + + S+ + R AA F + G Sbjct: 402 LKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSSAHLSLIREAANFKLKYG 461 Query: 266 SVDKALELLKKALQETPTSVLLHHQIGLCY 295 +A+ L++ ++ P + Q+ Y Sbjct: 462 RKKEAISDLEQLWKQNPKDIHTLAQLISAY 491 Score = 28.2 bits (61), Expect = 8.7, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 38/90 (42%), Gaps = 3/90 (3%) Query: 293 LCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVA--HLDLARMY 350 LCY A I + Q + +K + + R ++ E+ P E+A H +A + Sbjct: 178 LCYNAACALIGQGQLSQA-MKILQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYIL 236 Query: 351 IEAGNHRKAEENFQKLLCMKPVVEETMQDI 380 G +A + + +++ +KP + I Sbjct: 237 QLQGRTEEALQLYNQIIKLKPTDVGLLAVI 266 >4UZY-A nrPDB Length = 651 Score = 35.9 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 30/149 (20%), Positives = 53/149 (35%), Gaps = 17/149 (11%) Query: 325 AIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETM---QDIH 381 AI H + ++ P A L Y G + A + +++L+ + P E+ Sbjct: 36 AIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQMYEQLVTLYPSNEDYKLYYAQSL 95 Query: 382 FHYGRFQEFQK-----KSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALD 436 + G + E K + A+ L A EQ LT L K D Sbjct: 96 YKGGMYPEASKAVVKVEGHQKAVTTLLVACSYEQDDLT--GCRRQLDKCA-------PED 146 Query: 437 LESLSLLGFVYKLEGNMNEALEYYERALR 465 +++ G + EG A + + A++ Sbjct: 147 PDTMVNTGCIMFKEGKFEAARQKFNDAVQ 175 >5AEM-A nrPDB Length = 447 Score = 35.5 bits (80), Expect = 0.052, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 45/123 (36%), Gaps = 13/123 (10%) Query: 319 DKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPV---VEE 375 +R AI+ F + P + + +Y + G +A + FQ+L P + Sbjct: 90 LDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLYMYNPYDANILR 149 Query: 376 TMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKAL 435 + ++ Y R + ++I Y+K R+ + +L+ + A Sbjct: 150 ELAILYVDYDRIE--------DSIELYMKV--FNANVERREAILAALENALDSSDEESAA 199 Query: 436 DLE 438 + E Sbjct: 200 EGE 202 Score = 29.0 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 61/163 (37%), Gaps = 14/163 (8%) Query: 35 LENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQN-----EEALKSLK-EAENLMQEEHDN 88 + V D EF + ++ + L + K N L L+ +NL+ E N Sbjct: 277 FWDHVPDDSEFDNRRFKNSTFDSLLAAEKEKSYNIPIDIRVRLGLLRLNTDNLV--EALN 334 Query: 89 QANVRSLVTWGNFAWMYYHMGR-LAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGW 147 T+ + A +Y+ L A+ Y + ++ P E D + Sbjct: 335 HFQCLYDETFSDVADLYFEAATALTRAEKYKEAID-----FFTPLLSLEEWRTTDVFKPL 389 Query: 148 ALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDG 190 A ++YE AK +E ++ +P++ + A YRL+ Sbjct: 390 ARCYKEIESYETAKEFYELAIKSEPDDLDIRVSLAEVYYRLND 432 >5G04-X nrPDB Length = 599 Score = 35.5 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 59/165 (35%), Gaps = 7/165 (4%) Query: 316 EKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE---ENFQKLLCMKPV 372 + ++ AI HF A+ P + L Y+ + + R+A N K L Sbjct: 383 LRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQ 442 Query: 373 VEETMQDIHFHYGRFQEFQKKSDVNAIIH---YLKAIKIEQASLTRDKSINSLKKLVLRK 429 + + QE K A+ Y+KA+ + L+R++ L+ Sbjct: 443 TLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNA 502 Query: 430 LRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSV 474 L D +LG EA++ Y AL L + + S+ Sbjct: 503 LA-NQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSL 546 Score = 31.7 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 36/235 (15%), Positives = 81/235 (34%), Gaps = 22/235 (9%) Query: 244 LANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCY------KA 297 L + S Q + + AA R G V +A+ ++A++ P + + + CY + Sbjct: 368 LNSNSVQALLLKGAA--LRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIRE 425 Query: 298 QMIQIKEATKGQPRGQNREKLDKMI--------RSAIFHFESAVEKKPTFEVAHLDLARM 349 M+ K L + A + A+ ++P + A + A + Sbjct: 426 AMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAEL 485 Query: 350 YIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIE 409 + + L ++ +H G F A+ Y A+ ++ Sbjct: 486 LSREQKYEDGIALLRNAL-----ANQSDCVLHRILGDF-LVAVNEYQEAMDQYSIALSLD 539 Query: 410 QASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL 464 + + ++K + D++ + G LEG+ +EA ++ ++ Sbjct: 540 PNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQ 594 Score = 28.2 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 23/153 (15%), Positives = 47/153 (30%), Gaps = 30/153 (19%) Query: 323 RSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHF 382 A++ A++ A L G ++A +F++ + + P Sbjct: 356 SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPC---------- 405 Query: 383 HYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSL 442 + I YL + SI + + + ++L+L Sbjct: 406 --------RLDCYEGLIECYLAS-----------NSIREAMVMANNVYKTLGANAQTLTL 446 Query: 443 LGFVYKLEGNMNE-ALEYYERALRLAADFENSV 474 L V + E A ++AL D+ +V Sbjct: 447 LATVCLEDPVTQEKAKTLLDKALTQRPDYIKAV 479 >3Q15-A nrPDB Length = 378 Score = 35.5 bits (80), Expect = 0.056, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 55/142 (38%), Gaps = 24/142 (16%) Query: 352 EAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQE-FQKKSDVNAIIHYLKAIKIEQ 410 + + +A +++ P V + ++ FH+ + + K ++ H L+A+ I Q Sbjct: 113 DQKEYVEAIGYYREAEKELPFVSDDIEKAEFHFKVAEAYYHMKQTHVSMYHILQALDIYQ 172 Query: 411 ASLTRD-KSINSL---------KKLVLRKLRRKALDLE-------------SLSLLGFVY 447 ++I SL K + L LE SL + Y Sbjct: 173 NHPLYSIRTIQSLFVIAGNYDDFKHYDKALPHLEAALELAMDIQNDRFIAISLLNIANSY 232 Query: 448 KLEGNMNEALEYYERALRLAAD 469 G+ A+E++++A +++ + Sbjct: 233 DRSGDDQMAVEHFQKAAKVSRE 254 >3ZFW-A nrPDB Length = 263 Score = 35.1 bits (79), Expect = 0.059, Method: Composition-based stats. Identities = 42/270 (15%), Positives = 86/270 (31%), Gaps = 45/270 (16%) Query: 213 NPDNGYIKVLLALKLQDEGQEAEGEKYIEEALA--------NMSSQTYVFRYAAKFYRRK 264 +PD + +LAL +D+ + + + +ALA + + A Y ++ Sbjct: 19 HPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 78 Query: 265 GSVDKALELLKKALQET--------PTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNRE 316 G +A L K+AL+ P + L + Q E Sbjct: 79 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQ--------------GKAE 124 Query: 317 KLDKMIRSAIFHF-ESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEE 375 +++ R A+ + P +LA Y++ G ++ AE ++++L E Sbjct: 125 EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR---AHE 181 Query: 376 TMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKAL 435 +G + I + + + + Sbjct: 182 K------EFGSVN-----GENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPT 230 Query: 436 DLESLSLLGFVYKLEGNMNEALEYYERALR 465 +L LG +Y+ +G + A + A R Sbjct: 231 VNTTLRSLGALYRRQGKLEAAHTLEDCASR 260 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 47/144 (32%), Gaps = 40/144 (27%) Query: 346 LARMYIEAGNHRKAEENFQKLLCMKPVVEE-----------TMQDIHFHYGRFQEFQKKS 394 LA +Y + ++ A L ++ + ++ G+++E + Sbjct: 29 LALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 88 Query: 395 DVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMN 454 +A++I + L + + LS L + + +G Sbjct: 89 K--------RALEIREKVLGK----------------FHPDVAKQLSNLALLCQNQGKAE 124 Query: 455 EALEYYERALRLAADFENSVRQGP 478 E YY RAL + + R GP Sbjct: 125 EVEYYYRRALEIY-----ATRLGP 143 >5JZ6-A nrPDB Length = 429 Score = 35.1 bits (79), Expect = 0.066, Method: Composition-based stats. Identities = 43/212 (20%), Positives = 80/212 (37%), Gaps = 18/212 (8%) Query: 127 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 186 KL N F ++ E+D E L+ GK E A F++++ P++P + G A Sbjct: 3 KLLNKFDKTIKA-ELDAAE---KLRKRGK-IEEAVNAFKELVRKYPQSPRARYGKAQCED 57 Query: 187 RLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEK-----YIE 241 L K + ++ ++ L PD + L+LK + + Q+ G ++ Sbjct: 58 DLAE-KRRSNEVLRGAIETYQEVASL-PDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQ 115 Query: 242 EALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ--- 298 + + T + Y G D A ++ ++ L TP G KAQ Sbjct: 116 RLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKI 175 Query: 299 ---MIQIKEATKGQPRGQNREKLDKMIRSAIF 327 + +KE + G + + + A+ Sbjct: 176 AESIPYLKEGIESGDPGTDDGRFYFHLGDAMQ 207 >3ZN3-A nrPDB Length = 291 Score = 34.7 bits (78), Expect = 0.082, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 48/141 (34%), Gaps = 10/141 (7%) Query: 240 IEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK--- 296 +E + Y+ + YR++ KA++ LK + + P ++ L Sbjct: 145 LESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKAPFFWSAWLELSLSIDSLE 204 Query: 297 ------AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMY 350 +Q+ TK +L ++ SA A P A + Sbjct: 205 TLTTVVSQLPSTHIMTKI-FYVYASHELHQVNSSAYEKLAEAEIIFPNSRYLKTQRALLT 263 Query: 351 IEAGNHRKAEENFQKLLCMKP 371 ++ + +AE F+ +L P Sbjct: 264 YDSRDFDEAESLFENILTNDP 284 >4JA9-A nrPDB Length = 488 Score = 34.4 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 17/118 (14%), Positives = 42/118 (35%), Gaps = 21/118 (17%) Query: 254 FRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQ 313 + A Y + + A++ +A++ P++ + + L Y + + G Sbjct: 20 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAY----------LRTECYG- 68 Query: 314 NREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP 371 A+ A+E + + A + G R A +++ ++ +KP Sbjct: 69 ----------YALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP 116 >4I9E-A nrPDB Length = 383 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 33/229 (14%), Positives = 78/229 (34%), Gaps = 17/229 (7%) Query: 188 LDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANM 247 LD + H +SL+ R + L Y++ L +++ ++ + E Sbjct: 42 LDQMEEDQDLHLYYSLMEFRHNLMLE----YLEPLEKMRI---EEQPRLSDLLLEIDKKQ 94 Query: 248 SSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYK--AQMIQIKEA 305 + T + Y F+R +D+ A++ ++ + + Sbjct: 95 ARLTGLLEYYFNFFRGMYELDQ--REYLSAIKF---FKKAESKLIFVKDRIEKAEFFFKM 149 Query: 306 TKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQK 365 ++ + R A ++ H A +++ + A +FQK Sbjct: 150 SESYYYMKQTYFSMDYARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQK 209 Query: 366 LLCMKPVVEET--MQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQAS 412 M ++ M ++ G + Q + + AI ++ +AI + + S Sbjct: 210 AYSMAEAEKQPQLMGRTLYNIGLCKNSQSQYED-AIPYFKRAIAVFEES 257 >5OJ8-A nrPDB Length = 255 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 67/173 (38%), Gaps = 31/173 (17%) Query: 213 NPDNGYIKVLLALKLQDEGQEAEGEKYIEEALA--------NMSSQTYVFRYAAKFYRRK 264 +PD + +LAL +D+ + + + +ALA + + A Y ++ Sbjct: 88 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 147 Query: 265 GSVDKALELLKKALQET--------PTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNRE 316 G +A L K+AL+ P + + L + Q E Sbjct: 148 GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQ--------------GKYE 193 Query: 317 KLDKMIRSAIFHFESAV-EKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLC 368 +++ + A+ +++ + P +LA Y++ G ++AE ++++L Sbjct: 194 EVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILT 246 Score = 34.0 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 35/232 (15%), Positives = 73/232 (31%), Gaps = 78/232 (33%) Query: 245 ANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQET--------PTSVLLHHQIGLCYK 296 + ++ Y +G + A+ L K+AL++ P + + + L Y+ Sbjct: 44 YEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR 103 Query: 297 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKK-PTFEVAHLDLARMYIEAGN 355 Q + ++ A+ E + K P +LA +Y + G Sbjct: 104 DQ--------------NKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGK 149 Query: 356 HRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR 415 +++AE P+ + +A++I + L + Sbjct: 150 YKEAE----------PLCK-----------------------------RALEIREKVLGK 170 Query: 416 DKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLA 467 D + L+ L + + +G E YY+RAL + Sbjct: 171 D----------------HPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIY 206 Score = 33.6 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 55/149 (36%), Gaps = 25/149 (16%) Query: 253 VFRYAAKFYRRKGSVDKALELLKKAL-QETPTSVLLHHQIGLCYKAQMIQIKEATKGQPR 311 V+R K+ ++ AL + +K L ++ P + + + Y + + KEA +P Sbjct: 101 VYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLY-GKRGKYKEA---EPL 156 Query: 312 GQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLL---- 367 + ++ + + P +LA + G + + E +Q+ L Sbjct: 157 CKRALEIREKVLGKDH---------PDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQ 207 Query: 368 -CMKP------VVEETMQDIHFHYGRFQE 389 + P + + + G+F++ Sbjct: 208 TKLGPDDPNVAKTKNNLASCYLKQGKFKQ 236 >3NF1-A nrPDB Length = 311 Score = 34.0 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 36/238 (15%), Positives = 75/238 (31%), Gaps = 78/238 (32%) Query: 239 YIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQET--------PTSVLLHHQ 290 Y + + ++ Y +G + A+ L K+AL++ P + + Sbjct: 15 YFQGGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNI 74 Query: 291 IGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKK-PTFEVAHLDLARM 349 + L Y+ Q + ++ A+ E + K P +LA + Sbjct: 75 LALVYRDQ--------------NKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVL 120 Query: 350 YIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIE 409 Y + G +++AE P+ + +A++I Sbjct: 121 YGKRGKYKEAE----------PLCK-----------------------------RALEIR 141 Query: 410 QASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLA 467 + L +D + L+ L + + +G E YY+RAL + Sbjct: 142 EKVLGKD----------------HPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIY 183 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 67/173 (38%), Gaps = 31/173 (17%) Query: 213 NPDNGYIKVLLALKLQDEGQEAEGEKYIEEALA--------NMSSQTYVFRYAAKFYRRK 264 +PD + +LAL +D+ + + + +ALA + + A Y ++ Sbjct: 65 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 124 Query: 265 GSVDKALELLKKALQET--------PTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNRE 316 G +A L K+AL+ P + + L + Q E Sbjct: 125 GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQ--------------GKYE 170 Query: 317 KLDKMIRSAIFHFESAV-EKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLC 368 +++ + A+ +++ + P +LA Y++ G ++AE ++++L Sbjct: 171 EVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILT 223 >6FUZ-A nrPDB Length = 337 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 32/173 (18%), Positives = 62/173 (35%), Gaps = 31/173 (17%) Query: 213 NPDNGYIKVLLALKLQDEGQEAEGEKYIEEALA--------NMSSQTYVFRYAAKFYRRK 264 +PD + +LAL +D+ + + + +ALA + + A Y ++ Sbjct: 51 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKR 110 Query: 265 GSVDKALELLKKALQET--------PTSVLLHHQIGL-CYKAQMIQIKEATKGQPRGQNR 315 G +A L K+AL+ P + + L C + E + G + Sbjct: 111 GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQ 170 Query: 316 EKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLC 368 KL P +LA Y++ G ++AE ++++L Sbjct: 171 TKLGPD--------------DPNVAKTKNNLASCYLKQGKFKQAETLYKEILT 209 Score = 32.1 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 34/232 (14%), Positives = 73/232 (31%), Gaps = 78/232 (33%) Query: 245 ANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQET--------PTSVLLHHQIGLCYK 296 + ++ Y +G + A+ L K+AL++ P + + + L Y+ Sbjct: 7 YEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR 66 Query: 297 AQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKK-PTFEVAHLDLARMYIEAGN 355 Q + ++ A+ E + + P +LA +Y + G Sbjct: 67 DQ--------------NKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGK 112 Query: 356 HRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTR 415 +++AE P+ + +A++I + L + Sbjct: 113 YKEAE----------PLCK-----------------------------RALEIREKVLGK 133 Query: 416 DKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLA 467 D + L+ L + + +G E YY+RAL + Sbjct: 134 D----------------HPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIY 169 >5O09-1C nrPDB Length = 238 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 34/216 (15%), Positives = 72/216 (33%), Gaps = 24/216 (11%) Query: 257 AAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNRE 316 A +++G KA L ++AL + + + + + + Sbjct: 39 LADLRQKEGDFRKAESLYREALFRAQELRKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFY 98 Query: 317 KLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLL----CMKPV 372 +L I + E+ +E+ +LA ++ + +AE + + L + Sbjct: 99 ELALKISA-----ENGLEESDKVATIKNNLAMIFKQLRKFERAEGYYCEALETFQRLDGE 153 Query: 373 VEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRR 432 + ++ + G D ++H +A+ I Q L Sbjct: 154 QSARVASVYNNLGVLYYSHMDVDRAQVMH-ERALAIRQNLHEGQMDPADL---------- 202 Query: 433 KALDLESLSLLGFVYKLEGNMNEALEYYERALRLAA 468 ++ LG VYK G+ +A +RA R+ A Sbjct: 203 ----SQTFINLGAVYKAAGDFQKAEACVDRAKRIRA 234 >6AF0-A nrPDB Length = 939 Score = 33.2 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 62/153 (40%), Gaps = 13/153 (8%) Query: 157 YERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDN 216 Y RA F+K L++DP+N ++ G AI+ ++ K + F ++ + + Sbjct: 721 YNRAVEFFDKALQLDPKNAYAAQGIAIAL--VEDRKDYKNALQIF----IKVRETIQDAH 774 Query: 217 GYIK---VLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALEL 273 Y+ + L+ + E+ +E AN + + + KG ++ L+ Sbjct: 775 VYVNMGHIYAELRQFSKAIESYEIALSKEGKANDAGIISCL---GRTWLNKGRAERNLDA 831 Query: 274 LKKAL-QETPTSVLLHHQIGLCYKAQMIQIKEA 305 K AL Q + Q+ + +QI+ A Sbjct: 832 YKMALDQAKKAVAVAPDQLHFKFNVAFVQIQIA 864 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 42/229 (18%), Positives = 94/229 (41%), Gaps = 17/229 (7%) Query: 257 AAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNRE 316 AA+ K + +A L+K +Q + + +G Y ++ + A + + + Sbjct: 391 AAQLSVLKNDLGEAKLRLEKMIQHSKNYEAM-ILLGTLYAEEVFANQSAAVKEDKSAEAK 449 Query: 317 K---LDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKL--LCMKP 371 K L + +RSA + + L+LAR+Y E+ + KA + Q++ L + Sbjct: 450 KAISLLEGVRSAWKDPKRNLSPDAAVL---LNLARLY-ESESPDKALQCLQQVEQLEIDQ 505 Query: 372 VVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQAS--LTRDKSINSLKKLVLRK 429 + + + +K +++ + ++ L + +L Sbjct: 506 IPQSEYPPDAEDEAAARAAIRKLLPPQLLNNIGCFYSQEGKHRLATEFFQAALDSCARIS 565 Query: 430 LRRKALDLESL-----SLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 LD+++L LG Y+ EG++++A+E YE+ L +D+ ++ Sbjct: 566 QTENDLDIDALLTTIPFNLGRSYEYEGDIDKAIETYEQLLSRHSDYTDA 614 >4JHR-A nrPDB Length = 333 Score = 33.2 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 47/134 (35%), Gaps = 3/134 (2%) Query: 340 EVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAI 399 A +L GN +A Q+ L + + + + + Y + K Sbjct: 11 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGC 70 Query: 400 IHYLKAIKIEQASLTRDKSINSL--KKLVL-RKLRRKALDLESLSLLGFVYKLEGNMNEA 456 + + ++ L + L L L +A + LG + L GN +A Sbjct: 71 PGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDA 130 Query: 457 LEYYERALRLAADF 470 + +E+ L +A +F Sbjct: 131 VIAHEQRLLIAKEF 144 >5WQL-B nrPDB Length = 278 Score = 32.8 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 21/55 (38%) Query: 241 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCY 295 +ALA VF Y + + G+ D A E L+ PT H G+ Sbjct: 70 SQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIAL 124 Score = 31.3 bits (69), Expect = 0.85, Method: Composition-based stats. Identities = 45/189 (23%), Positives = 66/189 (34%), Gaps = 30/189 (15%) Query: 128 LSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYR 187 S R + PE+ G L + G N++ A F+ VLE+DP + I+ Y Sbjct: 69 FSQALAIRPDMPEVFNYLGIYLTQAG--NFDAAYEAFDSVLELDPTYNYAHLNRGIALYY 126 Query: 188 LDGFKLATKNHKPFSL----LPLR----QAVRLNPDNGYIKVLLALKLQDEGQEAEGEKY 239 KLA + F P R D K +L + +E G Sbjct: 127 GGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNI 186 Query: 240 IEEALANMSSQTYVFR--------------------YAAKFYRRKGSVDKALELLKKALQ 279 +E L N+S QT + R Y K+Y G +D A L K A+ Sbjct: 187 VEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVA 246 Query: 280 ETPTSVLLH 288 + + H Sbjct: 247 NNVHNFVEH 255 Score = 28.2 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 23/66 (34%), Gaps = 3/66 (4%) Query: 329 FESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPV---VEETMQDIHFHYG 385 F A+ +P L +AGN A E F +L + P ++ G Sbjct: 69 FSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGG 128 Query: 386 RFQEFQ 391 R + Q Sbjct: 129 RDKLAQ 134 >4CJ9-A nrPDB Length = 794 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 1/53 (1%) Query: 324 SAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEET 376 ++ +E PT +LA + AGN A + Q +L +KPV++E Sbjct: 359 GGAQALQAVIEHGPTLRQHGFNLADIVKMAGNIGGA-QALQAVLDLKPVLDEH 410 >6CR2-A nrPDB Length = 477 Score = 32.4 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 48/128 (37%), Gaps = 26/128 (20%) Query: 302 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKA-- 359 E K + + +++ + M+ + + P E+AH+ +A + AG H + Sbjct: 212 YMEIIKARRQAGSKKDSEDMVWNLMSCVYKNGTPVPDEEIAHMMIALLM--AGQHSSSST 269 Query: 360 ---------------EENFQKLLC-----MKPVVEETMQDIHFHYGRFQEFQKKSDVNAI 399 EE +Q+ + + P+ + +Q + H +E + I Sbjct: 270 ASWIVLRLATRPDIMEELYQEQIRVLGSDLPPLTYDNLQKLDLHAKVIKETLRL--HAPI 327 Query: 400 IHYLKAIK 407 ++A+K Sbjct: 328 HSIIRAVK 335 >4ABN-A nrPDB Length = 474 Score = 32.1 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 37/190 (19%), Positives = 71/190 (37%), Gaps = 22/190 (11%) Query: 208 QAVRLNPD---NGYIKVLLALKLQDEGQEA---EGEKYIEEALANMSSQTYVFRYAAKFY 261 +A+ + PD + + A+KL+ E EA GE Y ++ +++S F A Sbjct: 110 KALNVTPDYSPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKG--DVTSAHTCFSGALTHC 167 Query: 262 RRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQP----------- 310 + K S+ L ++ + LQ H + +A++ + G+ Sbjct: 168 KNKVSLQN-LSMVLRQLQTDSGDEHSRHVMDSVRQAKLAVQMDVLDGRSWYILGNAYLSL 226 Query: 311 --RGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLC 368 K+ + SA E K + HL+ A ++ ++ +A E F + Sbjct: 227 YFNTGQNPKISQQALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALEGFSQAAA 286 Query: 369 MKPVVEETMQ 378 + P E Q Sbjct: 287 LDPAWPEPQQ 296 >5MGX-E nrPDB Length = 290 Score = 32.1 bits (71), Expect = 0.58, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 32/83 (38%), Gaps = 1/83 (1%) Query: 219 IKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKAL 278 + L A +L+ + A L + K ++G +A+ +L+ AL Sbjct: 185 LNNLAASQLKLDHYRAALRS-CSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAAL 243 Query: 279 QETPTSVLLHHQIGLCYKAQMIQ 301 + P++ +H ++ K Q Sbjct: 244 KLEPSNKTIHAELSKLVKKHAAQ 266 Score = 29.4 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 30/76 (39%), Gaps = 2/76 (2%) Query: 296 KAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGN 355 +AQ++Q+K + R+A+ +E +P A ++ + G Sbjct: 174 EAQLLQLKVKCLNNLAASQLK--LDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGE 231 Query: 356 HRKAEENFQKLLCMKP 371 + +A + L ++P Sbjct: 232 YSEAIPILRAALKLEP 247 >5LJ5-S nrPDB Length = 687 Score = 31.7 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 35/199 (17%), Positives = 74/199 (37%), Gaps = 23/199 (11%) Query: 138 CPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKN 197 CP+ +G+ L+ K ++R + +EK +E P + + + Y L + Sbjct: 434 CPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGI 493 Query: 198 HKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYA 257 + + L+ ++ ++ + L +KYI +++ F A Sbjct: 494 Y----------TIALDENSDFLTKEAKIVL--------LQKYIT-----FETESQEFEKA 530 Query: 258 AKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREK 317 K YRR +++ TS Q+ K Q + E + + +N+ + Sbjct: 531 RKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIEFEITDENKLE 590 Query: 318 LDKMIRSAIFHFESAVEKK 336 K+ AI F+ +K+ Sbjct: 591 ARKVFEEAIVFFKEKDDKQ 609 Score = 28.2 bits (61), Expect = 7.7, Method: Composition-based stats. Identities = 42/225 (18%), Positives = 79/225 (35%), Gaps = 30/225 (13%) Query: 258 AKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREK 317 AKF R V KA ++L KA IGLC KA+ KG + + K Sbjct: 411 AKFLIRHDDVPKARKILGKA-------------IGLCPKAKTF------KGYIELEVKLK 451 Query: 318 LDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP--VVEE 375 +R +E +E +P+ + G+ + + L + +E Sbjct: 452 EFDRVRKI---YEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKE 508 Query: 376 TMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLT---RDKSINSLKKLVLRKLRR 432 + Y F+ ++ + A Y + +++ Q S + + L Sbjct: 509 AKIVLLQKYITFETESQEFE-KARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDL 567 Query: 433 KALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQG 477 L E++ + N EA + +E A+ + ++ +QG Sbjct: 568 AKLQSENVDEDIEFEITDENKLEARKVFEEAIVFFKEKDD--KQG 610 >3LY9-A nrPDB Length = 372 Score = 31.7 bits (70), Expect = 0.80, Method: Composition-based stats. Identities = 27/179 (15%), Positives = 58/179 (32%), Gaps = 35/179 (19%) Query: 240 IEEALANMSSQTYVFRYAAKFYRRKG--------SVDKALELLKKALQETPTSVLLHHQI 291 ++E L + FY+ S+++A ELL + +Q +P + Sbjct: 182 MQETLQKILPHRGAL--LTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEK 239 Query: 292 GLC----YKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEK------KPTFE- 340 L + + K+ N L ++ +I + AV +++ Sbjct: 240 ALVDIVRHSQHPLDEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQA 299 Query: 341 -----------VAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQ 388 + ++ L ++Y G +R+A + ++P G FQ Sbjct: 300 INTGIDLEMSWLNYVLLGKVYEMKGMNREAANAYLTAFNLRP---GANTLYWIENGIFQ 355 >4CGU-A nrPDB Length = 112 Score = 31.3 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 28/73 (38%) Query: 302 IKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEE 361 + + Q N + R A+ ++ + +P V + + A I+ G + +A + Sbjct: 1 LMSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQ 60 Query: 362 NFQKLLCMKPVVE 374 Q+ L E Sbjct: 61 MCQQGLRYTSTAE 73 >6C95-A nrPDB Length = 866 Score = 31.3 bits (69), Expect = 0.96, Method: Composition-based stats. Identities = 45/250 (18%), Positives = 87/250 (34%), Gaps = 32/250 (12%) Query: 224 ALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPT 283 L L G++ E + + L N + R D+A++ + AL+ Sbjct: 53 GLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKD 112 Query: 284 SVLLHHQIGLC------------YKAQMIQIKEATKGQPRG----QNREKLDKMIRSAIF 327 ++ + + L + Q++Q++ A + G + + +M + Sbjct: 113 NLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILE 172 Query: 328 HFESAVEKKPTFEV-AHLDL----ARMYIEAGNHRKAEE---NFQKLLCMKPVVEETMQD 379 F + P + +L ++ EAG +R+A E ++K +C K VEET + Sbjct: 173 EFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGE 232 Query: 380 IHFHYGRFQ--------EFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLR 431 + R + ++ + A L+ L R K R L Sbjct: 233 LLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLV 292 Query: 432 RKALDLESLS 441 + L L LS Sbjct: 293 PRRLPLNFLS 302 >1A17-A nrPDB Length = 166 Score = 31.3 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 16/118 (13%), Positives = 40/118 (33%), Gaps = 21/118 (17%) Query: 254 FRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQ 313 + A Y + + A++ +A++ P++ + + L Y Sbjct: 16 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLR---------------- 59 Query: 314 NREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKP 371 + A+ A+E + + A + G R A +++ ++ +KP Sbjct: 60 -----TECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP 112 >5O6D-A nrPDB Length = 545 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 60 YVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSL 95 ++K +K +E L+++K E LMQ H N A R L Sbjct: 386 FMKRVKTDDEVVLENIKRKEQLMQTIHQNSAGKRRL 421 >3JCM-G nrPDB Length = 899 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 2/39 (5%) Query: 252 YVFRYAAKFYR--RKGSVDKALELLKKALQETPTSVLLH 288 V Y AK R G++D+A L+ +ALQ+ P++ LL Sbjct: 736 DVLFYIAKIQMEIRLGNLDQAELLVTQALQKFPSNALLW 774 >6ICZ-I nrPDB Length = 855 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 47/130 (36%), Gaps = 14/130 (10%) Query: 151 KCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAV 210 + GG+ ERA+ FE+ L+ P YA + Y L ++ +A Sbjct: 567 RYGGRKLERARDLFEQALDGCPPK------YAKTLYLLYAQLEEEWGLARHAMAVYERAT 620 Query: 211 R-LNPDNGYIKVLLALKLQDE-----GQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRK 264 R + P Y + +K E +K IE + + R+ A + Sbjct: 621 RAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSDEHAREM-CLRF-ADMECKL 678 Query: 265 GSVDKALELL 274 G +D+A + Sbjct: 679 GEIDRARAIY 688 Score = 27.8 bits (60), Expect = 9.9, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 46/145 (31%), Gaps = 18/145 (12%) Query: 272 ELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFES 331 +L ++AL+ P S L ++ KA+ Q+K P ++ E Sbjct: 55 QLYERALKLLPCSYKLWYRY---LKARRAQVKHRCVTDPAYEDVNN----------CHER 101 Query: 332 AVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVV-EETMQDIHFHYGRFQEF 390 A LD + ++ G F + L P+ + ++ + Sbjct: 102 AFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPLYLRF----LR 157 Query: 391 QKKSDVNAIIHYLKAIKIEQASLTR 415 A+ Y + +K+ S Sbjct: 158 SHPLPETAVRGYRRFLKLSPESAEE 182 >2CJQ-A nrPDB Length = 720 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 43/263 (16%), Positives = 94/263 (35%), Gaps = 29/263 (11%) Query: 164 FEKVLEVDPENPESSAGYAISAYRL--DGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKV 221 FE++L P +S+ G+ SAY+L ++ ++ P R+ V+++P Y+K+ Sbjct: 18 FEELLLRCPPKIKSNKGHMASAYQLAQGNWEPLDCGVHLGTI-PARR-VKIHPYEAYLKL 75 Query: 222 LLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRK----GSVDKALE----- 272 L E +E + + + R+ +K G + + L+ Sbjct: 76 KDLL----EEEEKKPKCRDTVIREHNKWILKKVRHQGNLNTKKTLNPGKLSEQLDREGHK 131 Query: 273 --LLKKALQETPTSVLLHHQIGLCYKAQ--MIQIKEATKGQPRGQNREKLDKMIRSAIFH 328 + + T + + +AQ EA + + ++ + + Sbjct: 132 RNIYNNQIGTIMTEAGIRLEKLPVVRAQTDTKSFHEAIRDKIDKNENQQSPGLHDKLLEI 191 Query: 329 FESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQ 388 F + + P+ + D+ +EAG +RK F + + V++ + Q Sbjct: 192 FHTIAQ--PSLRHTYSDVTWEQLEAGVNRKGAAGFLEKKNVGEVLDSEKHLVE------Q 243 Query: 389 EFQKKSDVNAIIHYLKAIKIEQA 411 + I +Y AI + Sbjct: 244 LIRDLKTGRKIRYYETAIPKNEK 266 >3J98-H nrPDB Length = 297 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 20/143 (13%), Positives = 51/143 (35%), Gaps = 26/143 (18%) Query: 234 AEGEKYIEEALANMSSQT-----YVFRYAAKFYRRKGSVDKALELLKKALQETPTS---- 284 A G + + A ++ Q+ F A ++ K +A+ L +A++ Sbjct: 62 AAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFK-KADPQEAINCLMRAIEIYTDMGRFT 120 Query: 285 -VLLHH-QIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVA 342 HH I Y+ +++ +++A + + + E + Sbjct: 121 IAAKHHISIAEIYETELVDVEKAIAHYEQSAD--------------YYKGEESNSSANKC 166 Query: 343 HLDLARMYIEAGNHRKAEENFQK 365 L +A + ++KA + +++ Sbjct: 167 LLKVAGYAAQLEQYQKAIDIYEQ 189 >3OKY-A nrPDB Length = 681 Score = 29.4 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 40/190 (21%), Positives = 62/190 (32%), Gaps = 37/190 (19%) Query: 157 YERAKACFEKVLEVDPENPE----SSAG---YAISAYRLDGFKLATKNHKPFSLLPLRQA 209 Y A F L V PE P+ +SAG Y RL ++ R Sbjct: 214 YGFASGGFVYFLTVQPETPDGMAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAG 273 Query: 210 VRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDK 269 V ++L A L G EA + + N+SS V A F + + Sbjct: 274 VEY-------RLLQAAYLAKPG-EALAQAF------NISSDEDVL--FAIFSKGQ----- 312 Query: 270 ALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHF 329 K P L +A +QIKE + G+ +L+ ++ + Sbjct: 313 ------KQYHHPPDDSAL---CAFPIRAINLQIKERLQSCYHGEGNLELNWLLGKDVQCT 363 Query: 330 ESAVEKKPTF 339 ++ V F Sbjct: 364 KAPVPIDDNF 373 >3AL9-A nrPDB Length = 539 Score = 29.4 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 40/190 (21%), Positives = 62/190 (32%), Gaps = 37/190 (19%) Query: 157 YERAKACFEKVLEVDPENPE----SSAG---YAISAYRLDGFKLATKNHKPFSLLPLRQA 209 Y A F L V PE P+ +SAG Y RL ++ R Sbjct: 215 YGFASGGFVYFLTVQPETPDGMAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAG 274 Query: 210 VRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDK 269 V ++L A L G EA + + N+SS V A F + + Sbjct: 275 VEY-------RLLQAAYLAKPG-EALAQAF------NISSDEDVL--FAIFSKGQ----- 313 Query: 270 ALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHF 329 K P L +A +QIKE + G+ +L+ ++ + Sbjct: 314 ------KQYHHPPDDSAL---CAFPIRAINLQIKERLQSCYHGEGNLELNWLLGKDVQCT 364 Query: 330 ESAVEKKPTF 339 ++ V F Sbjct: 365 KAPVPIDDNF 374 >4KVO-A nrPDB Length = 731 Score = 29.0 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 28/56 (50%) Query: 222 LLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKA 277 LA G+ + EKY++ A+ + + +F A+ + KG + A+E++ A Sbjct: 385 FLAQHFDHVGELEKAEKYVDLAIDHTPTLVELFMTKARISKHKGELQTAMEIMDHA 440 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.125 0.329 Lambda K H 0.267 0.0387 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,464,390 Number of Sequences: 36641 Number of extensions: 612405 Number of successful extensions: 2455 Number of sequences better than 10.0: 65 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 49 Number of HSP's that attempted gapping in prelim test: 2115 Number of HSP's gapped (non-prelim): 291 length of query: 478 length of database: 10,336,785 effective HSP length: 101 effective length of query: 377 effective length of database: 6,636,044 effective search space: 2501788588 effective search space used: 2501788588 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)