BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09488 (218 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1XWK-A nrPDB 452 e-128 4GTU-A nrPDB 402 e-113 1HNA-A nrPDB 387 e-108 2DC5-A nrPDB 384 e-107 1B4P-A nrPDB 380 e-106 5FWG-A nrPDB 377 e-105 3GTU-B nrPDB 335 1e-92 1GSU-A nrPDB 299 7e-82 5AN1-A nrPDB 233 4e-62 2FHE-A nrPDB 210 3e-55 4Q5Q-A nrPDB 202 1e-52 2WRT-A nrPDB 196 7e-51 1FHE-A nrPDB 187 3e-48 1BG5-A nrPDB 159 6e-40 1B8X-A nrPDB 159 1e-39 1DUG-A nrPDB 159 1e-39 4WR5-A nrPDB 153 6e-38 2GSR-A nrPDB 115 1e-26 5D73-A nrPDB 108 2e-24 2GLR-A nrPDB 102 2e-22 1TU7-A nrPDB 100 6e-22 18GS-A nrPDB 100 6e-22 5Y9Z-A nrPDB 78 4e-15 3KXO-A nrPDB 74 5e-14 2AAW-A nrPDB 72 2e-13 1M0U-A nrPDB 65 3e-11 1F3B-A nrPDB 63 7e-11 5LCZ-A nrPDB 63 1e-10 1EV4-A nrPDB 63 1e-10 1B48-A nrPDB 59 1e-09 1GSQ-A nrPDB 59 2e-09 2VCT-A nrPDB 57 5e-09 4Q5F-A nrPDB 57 6e-09 2VCV-A nrPDB 55 2e-08 3I6A-A nrPDB 54 4e-08 1ZL9-A nrPDB 54 6e-08 1PL2-A nrPDB 54 7e-08 2WDU-A nrPDB 52 2e-07 1YQ1-A nrPDB 51 5e-07 1U3I-A nrPDB 50 8e-07 2CA8-A nrPDB 50 8e-07 1GUL-A nrPDB 47 5e-06 6F05-A nrPDB 46 1e-05 1VF1-A nrPDB 44 7e-05 4PNG-A nrPDB 41 4e-04 5F07-A nrPDB 40 0.001 2HNL-A nrPDB 39 0.002 4MPF-A nrPDB 36 0.015 1N2A-A nrPDB 31 0.32 1AW9-A nrPDB 31 0.35 3LFL-A nrPDB 31 0.50 1GPI-A nrPDB 31 0.51 5O3Z-A nrPDB 30 0.58 2C3Q-A nrPDB 30 0.58 3R3J-A nrPDB 30 0.61 4RI7-A nrPDB 30 0.65 4YH2-A nrPDB 30 0.81 4CHS-A nrPDB 30 0.85 3VWX-A nrPDB 30 1.0 3TOT-A nrPDB 30 1.1 3M8N-A nrPDB 29 1.2 2AYN-A nrPDB 29 1.2 5GJQ-x nrPDB 29 1.3 4XEB-A nrPDB 29 1.3 4MDC-A nrPDB 29 1.5 2PBJ-A nrPDB 29 1.5 3KUK-A nrPDB 29 1.5 2MMA-A nrPDB 28 3.2 1JLV-A nrPDB 28 3.9 2VO4-A nrPDB 28 4.1 4V1Z-A nrPDB 28 4.3 5EY6-A nrPDB 27 4.7 4HQS-A nrPDB 27 5.5 4EVM-A nrPDB 27 6.5 4YDH-A nrPDB 27 8.9 1PN9-A nrPDB 27 9.0 >1XWK-A nrPDB Length = 218 Score = 452 bits (1163), Expect = e-128, Method: Compositional matrix adjust. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL Sbjct: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF Sbjct: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >4GTU-A nrPDB Length = 217 Score = 402 bits (1032), Expect = e-113, Method: Compositional matrix adjust. Identities = 188/216 (87%), Positives = 203/216 (93%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY Sbjct: 2 MTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 61 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQ MD QL +CY+P+FEK Sbjct: 62 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEK 121 Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182 LKP+YLEELP ++ +S+FLGKRPWF G+KITFVDFL YDVLDLHRIFEP CLDAFPNLK Sbjct: 122 LKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNLK 181 Query: 183 DFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 DFISRFEGLEKISAYMKSSRFLP+P+++++AVWGNK Sbjct: 182 DFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >1HNA-A nrPDB Length = 217 Score = 387 bits (995), Expect = e-108, Method: Compositional matrix adjust. Identities = 182/217 (83%), Positives = 203/217 (93%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PM LGYW+IRGLAH+IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YLIDG HKITQSNAIL YIARKHNLCGE+E+E+IR DILENQ MD+ MQL +CY+P+FE Sbjct: 61 YLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFE 120 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 KLKP+YL+ LPE LKLYS+FLGK+PWF G+KITFVDF+ YDVL+ +++FEP CLDAFPNL Sbjct: 121 KLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNL 180 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 KDFISRFEGLEKISAYMKSSRFLPRPVF+KMAV+GNK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >2DC5-A nrPDB Length = 231 Score = 384 bits (985), Expect = e-107, Method: Compositional matrix adjust. Identities = 177/217 (81%), Positives = 199/217 (91%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPM LGYWDIRGLAHAIRL LEYTDSSYEEK+YTMGDAPDYD+SQWLNEKFKLGLDFPNL Sbjct: 8 MPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNL 67 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PYLIDG+HKITQSNAIL Y+ RKHNLCGETEEE+IRVDILENQ MDN M L +CYN +F Sbjct: 68 PYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADF 127 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 EKLKP YLE+LP ++LYSEFLGKRPWFAG+KITFVDF+ YDVL+ +++FE KCLDAFPN Sbjct: 128 EKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPN 187 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 LKDFI+RFEGL+KIS YMK+SRFLPRP+F+KMA WG+ Sbjct: 188 LKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGS 224 >1B4P-A nrPDB Length = 217 Score = 380 bits (977), Expect = e-106, Method: Compositional matrix adjust. Identities = 175/217 (80%), Positives = 199/217 (91%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YLIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IRVD+LENQ MD +QL M+CY+P+FE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFE 120 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 + KP+YLE LPEK+KLYSEFLGK+PWFAGNKIT+VDFLVYDVLD HRIFEPKCLDAFPNL Sbjct: 121 RKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNL 180 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 KDF++RFEGL+KIS YMKS RFL +P+F+KMA W K Sbjct: 181 KDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >5FWG-A nrPDB Length = 217 Score = 377 bits (968), Expect = e-105, Method: Compositional matrix adjust. Identities = 172/217 (79%), Positives = 199/217 (91%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YLIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IR DI+ENQ MDN MQL M+CYNP+FE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 120 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 K KP++L+ +PEK+KLYSEFLGKRPWFAG+K+T+VDFL YD+LD + IFEPKCLDAFPNL Sbjct: 121 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 180 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 KDF++RFEGL+KISAYMKSSR+L P+FSK+A W NK Sbjct: 181 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >3GTU-B nrPDB Length = 224 Score = 335 bits (858), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 158/216 (73%), Positives = 185/216 (85%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M+LGYWDIRGLAHAIRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLPY Sbjct: 6 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 65 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 L+DG +KITQSNAIL YIARKHN+CGETEEEKIRVDI+ENQ MD QL +CY+ + EK Sbjct: 66 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 125 Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182 LKP+YLEELP +LK +S FLGK WFAG K+TFVDFL YD+LD +RIF+PKCLD FPNLK Sbjct: 126 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 185 Query: 183 DFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 F+ RFE LEKI+AY++S +F P+ +KMA WGNK Sbjct: 186 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >1GSU-A nrPDB Length = 219 Score = 299 bits (765), Expect = 7e-82, Method: Compositional matrix adjust. Identities = 142/216 (65%), Positives = 166/216 (76%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 + LGYWDIRGLAHAIRLLLEYT++ Y+E++Y G APD+D S W NEK KLGLDFPNLPY Sbjct: 2 VTLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPY 61 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 LIDG K+TQSNAIL YIARKHN+CGETE EK RVD+LEN MD M +CY+P+FEK Sbjct: 62 LIDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEK 121 Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182 LKP YLE+LP KL+ S FLG R WF G+K+TFVDFL YDVLD R+F P C + NL Sbjct: 122 LKPAYLEQLPGKLRQLSRFLGSRSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQGNLS 181 Query: 183 DFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 F+ RFE LEKISAYM+S RF+ P+F A+W NK Sbjct: 182 QFLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >5AN1-A nrPDB Length = 219 Score = 233 bits (595), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 113/210 (53%), Positives = 141/210 (67%), Gaps = 2/210 (0%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 +LGYW R L IRL+L YT + +EEK Y +GDAPDYD+S+WL KFKLGL FPNLPY Sbjct: 4 VLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPYY 63 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKL 123 IDG KITQS AI+ Y+ARKH LCG T EE +R D++E Q D H + Y E + Sbjct: 64 IDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTY--EHYEQ 121 Query: 124 KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKD 183 K Y LP KL+ YS+FLG RPWFAG+K+T++DFL Y++ D H + CLD F NL+ Sbjct: 122 KDAYTASLPAKLRQYSDFLGSRPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDGFKNLQA 181 Query: 184 FISRFEGLEKISAYMKSSRFLPRPVFSKMA 213 F RFE LE I YM S +FL +P+ +K A Sbjct: 182 FQKRFEDLEAIKKYMASPKFLKKPICNKYA 211 >2FHE-A nrPDB Length = 216 Score = 210 bits (535), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 105/216 (48%), Positives = 138/216 (63%), Gaps = 5/216 (2%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW IRGL +RLLLEY YEE+ Y D +W ++KF+LGLD PNLP Sbjct: 1 PAKLGYWKIRGLQQPVRLLLEYLGEKYEEQIYERDDG-----EKWFSKKFELGLDLPNLP 55 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 Y ID K+TQS AIL YIA KH + G T EE+ RV ++E +D + I Y P+FE Sbjct: 56 YYIDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFE 115 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 +LK YL++LP +K++S+FLGK P+ G ++ VDF+VY+ LD R EP CLD FPNL Sbjct: 116 QLKEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNL 175 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 + F+SR E L I AYM+S+RF+ P+ A +G Sbjct: 176 QQFMSRIEALPSIKAYMESNRFIKWPLNGWHAQFGG 211 >4Q5Q-A nrPDB Length = 219 Score = 202 bits (513), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 99/212 (46%), Positives = 140/212 (66%), Gaps = 2/212 (0%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYWDIRG A IRLLL Y+ + +K+Y +G APD+DRS+WLNEKF LGLDFPNLPY Sbjct: 5 ILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPYY 64 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKL 123 IDG K+TQ+ AIL Y+ RK+ L G + E+IR+ + E QT D + +CY+ +KL Sbjct: 65 IDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANCDKL 124 Query: 124 KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKD 183 KP YL+ LP+ LKL S+F+G+ + AG I++VDF +Y+ L ++ P+ F NLK Sbjct: 125 KPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVPEVFGQFENLKR 184 Query: 184 FISRFEGLEKISAYMKSSRFLPRPVFSKMAVW 215 ++ R E L ++S Y+K + P+ + + W Sbjct: 185 YVERMESLPRVSDYIKKQQ--PKTFNAPTSKW 214 >2WRT-A nrPDB Length = 218 Score = 196 bits (497), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 107/217 (49%), Positives = 140/217 (64%), Gaps = 5/217 (2%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MP LGYW IRGL +RLLLEY YEE Y D R +WL +KF +GLD PNL Sbjct: 1 MPAKLGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRDD-----REKWLGDKFNMGLDLPNL 55 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PY ID K+TQS AI+ YIA KH + G T EE+ R+ ++E MD M +CYNP+F Sbjct: 56 PYYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCYNPKF 115 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 E++K YL+ELP LK++S FLG R + G+ ++ VDF+VY+ LD R P+CL+ FP Sbjct: 116 EEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPK 175 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 LK+F SR E L KI AYM+S +F+ P+ S +A +G Sbjct: 176 LKEFKSRIEDLPKIKAYMESEKFIKWPLNSWIASFGG 212 >1FHE-A nrPDB Length = 217 Score = 187 bits (475), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 104/215 (48%), Positives = 141/215 (65%), Gaps = 5/215 (2%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW +RGLA +RL LEY YEE Y D R +W++EKF +GLD PNLP Sbjct: 1 PAKLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDD-----REKWMSEKFNMGLDLPNLP 55 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 Y ID K+TQS AI+ YIA KH + G T EE+ R+ ++E MD + G +CYNP+FE Sbjct: 56 YYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNPKFE 115 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 ++K +Y++ELP+ LK++S+FLG R + G+ ++ VDF++Y+ LD R P CLD FP L Sbjct: 116 EVKEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPKL 175 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWG 216 K+F SR E L KI AYM+S RF+ P+ A +G Sbjct: 176 KEFKSRIEALPKIKAYMESKRFIKWPLNGWAASFG 210 >1BG5-A nrPDB Length = 254 Score = 159 bits (403), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 92/217 (42%), Positives = 131/217 (60%), Gaps = 5/217 (2%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M ILGYW I+GL RLLLEY + YEE Y + +W N+KF+LGL+FPNL Sbjct: 1 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNL 55 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PY IDG K+TQS AI+ YIA KHN+ G +E+ + +LE +D + I Y+ +F Sbjct: 56 PYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDF 115 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 E LK +L +LPE LK++ + L + + G+ +T DF++YD LD+ +P CLDAFP Sbjct: 116 ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 175 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 L F R E + +I Y+KSS+++ P+ A +G Sbjct: 176 LVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 212 >1B8X-A nrPDB Length = 280 Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 91/214 (42%), Positives = 130/214 (60%), Gaps = 5/214 (2%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYW I+GL RLLLEY + YEE Y + +W N+KF+LGL+FPNLPY Sbjct: 3 ILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLPYY 57 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKL 123 IDG K+TQS AI+ YIA KHN+ G +E+ + +LE +D + I Y+ +FE L Sbjct: 58 IDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETL 117 Query: 124 KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKD 183 K +L +LPE LK++ + L + + G+ +T DF++YD LD+ +P CLDAFP L Sbjct: 118 KVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVC 177 Query: 184 FISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 F R E + +I Y+KSS+++ P+ A +G Sbjct: 178 FKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >1DUG-A nrPDB Length = 234 Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 91/214 (42%), Positives = 130/214 (60%), Gaps = 5/214 (2%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYW I+GL RLLLEY + YEE Y + +W N+KF+LGL+FPNLPY Sbjct: 3 ILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLPYY 57 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKL 123 IDG K+TQS AI+ YIA KHN+ G +E+ + +LE +D + I Y+ +FE L Sbjct: 58 IDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETL 117 Query: 124 KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKD 183 K +L +LPE LK++ + L + + G+ +T DF++YD LD+ +P CLDAFP L Sbjct: 118 KVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVC 177 Query: 184 FISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 F R E + +I Y+KSS+++ P+ A +G Sbjct: 178 FKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >4WR5-A nrPDB Length = 244 Score = 153 bits (386), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 88/214 (41%), Positives = 126/214 (58%), Gaps = 5/214 (2%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYW I+GL RLLLE + YEE + +W N+KF+LGL+FPNLPY Sbjct: 28 ILGYWKIKGLVQPTRLLLEXLEEKYEEHLXERDEG-----DKWRNKKFELGLEFPNLPYX 82 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKL 123 IDG K+TQS AI+ IA KHN+ G +E+ + +LE +D + I Y+ +FE L Sbjct: 83 IDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETL 142 Query: 124 KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKD 183 K +L +LPE LK++ + L + G+ +T DF++YD LD+ +P CLDAFP L Sbjct: 143 KVDFLSKLPEMLKMFEDRLCHKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAFPKLVC 202 Query: 184 FISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 F R E + +I Y+KSS+++ P+ A +G Sbjct: 203 FKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 236 >2GSR-A nrPDB Length = 207 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 69/211 (32%), Positives = 110/211 (52%), Gaps = 15/211 (7%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ +RG A+R+LL D S++E+ TM P K F LP Sbjct: 2 PYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTMETWP----------PLKPSCLFRQLP 51 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 DG + QSNAIL ++ R L G+ ++E VD++ + D + + Y +E Sbjct: 52 KFQDGDLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYT-NYE 110 Query: 122 KLKPKYLEELPEKLK----LYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDA 177 K KY++ELPE LK L S+ G + + G++I+F D+ + D+L +H++ P CLDA Sbjct: 111 AGKEKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDA 170 Query: 178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 FP L +++R KI A++ S + RP+ Sbjct: 171 FPLLSAYVARLSARPKIKAFLASPEHVNRPI 201 >5D73-A nrPDB Length = 208 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 72/213 (33%), Positives = 104/213 (48%), Gaps = 16/213 (7%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+ IRGLA IRL+L + + + D P K F L Sbjct: 1 MSYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWP----------SMKSHFHFGQL 50 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 P L DG H+I QS AIL ++ARKHNL G E E +D+ D H + + Y + Sbjct: 51 PCLYDGDHQIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQA-Y 109 Query: 121 EKLKPKYLEE-LPEKLKLYSEFLGKRP----WFAGNKITFVDFLVYDVLDLHRIFEPKCL 175 + K Y+++ LP +L + + L R + G KI++VDF++++ LD+H+I +P CL Sbjct: 110 DTEKDSYIKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCL 169 Query: 176 DAFPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 D FP LK + R E + Y K PV Sbjct: 170 DKFPLLKAYHQRMEDRPGLKEYCKQRNRAKIPV 202 >2GLR-A nrPDB Length = 209 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 61/211 (28%), Positives = 106/211 (50%), Gaps = 13/211 (6%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ +RG A+R+LL S++E+ T+ W+ K + LP Sbjct: 2 PYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTI--------DTWMQGLLKPTCLYGQLP 53 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 DG + QSNAIL ++ R L G+ + E ++D++ + D + + Y +E Sbjct: 54 KFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYT-NYE 112 Query: 122 KLKPKYLEELPEKLK----LYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDA 177 K Y++ LP LK L S+ G + + G++I+F D+ + D+L +H++ P CLD Sbjct: 113 NGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDN 172 Query: 178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 FP L +++R KI A++ S + RP+ Sbjct: 173 FPLLSAYVARLSARPKIKAFLSSPEHVNRPI 203 >1TU7-A nrPDB Length = 208 Score = 100 bits (248), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 71/213 (33%), Positives = 105/213 (49%), Gaps = 16/213 (7%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+ IRGLA IRL L D + + D D + +F+ G L Sbjct: 1 MSYKLTYFSIRGLAEPIRLFLVDQDIKF------IDDRIAKDDFSSIKSQFQFG----QL 50 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 P L DG +I QS AIL ++ARK+NL GE E E +D+ D H++ + Y + Sbjct: 51 PCLYDGDQQIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMA-Y 109 Query: 121 EKLKPKYLEE-LPEKLKLYSEFLGKRP----WFAGNKITFVDFLVYDVLDLHRIFEPKCL 175 E K Y++ LP +L + + L R G+KI++ D+ +++ LD+H+I +P CL Sbjct: 110 ETEKDPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCL 169 Query: 176 DAFPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 D FP LK F R + K+ Y + PV Sbjct: 170 DKFPLLKVFHQRMKDRPKLKEYCEKRDAAKVPV 202 >18GS-A nrPDB Length = 210 Score = 100 bits (248), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 60/211 (28%), Positives = 104/211 (49%), Gaps = 13/211 (6%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ +RG A+R+LL S++E+ T+ W K + LP Sbjct: 3 PYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLP 54 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 DG + QSN IL ++ R L G+ ++E VD++ + D + + Y +E Sbjct: 55 KFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYE 113 Query: 122 KLKPKYLEELPEKLK----LYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDA 177 K Y++ LP +LK L S+ G + + G++I+F D+ + D+L +H + P CLDA Sbjct: 114 AGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDA 173 Query: 178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 FP L ++ R K+ A++ S ++ P+ Sbjct: 174 FPLLSAYVGRLSARPKLKAFLASPEYVNLPI 204 >5Y9Z-A nrPDB Length = 199 Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 59/200 (29%), Positives = 96/200 (48%), Gaps = 20/200 (10%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+++RG A IR + Y D YE+ + D P K K L F +P L Sbjct: 6 LLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWP----------KIKPTLPFGKIPVLE 55 Query: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLK 124 + QS AI Y+ + +L G+TE E+ +VD + + T+D+ M L + E + LK Sbjct: 56 VEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVD-TLDDFMSL--FPWAEENQDLK 112 Query: 125 PKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLH-RIFEPKCLDAF 178 + +L P LK +LG + WF GN +T+ DF +D+ + +P L + Sbjct: 113 ERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADF-YWDICSTTLLVLKPDLLGIY 171 Query: 179 PNLKDFISRFEGLEKISAYM 198 P L ++ + + ISA++ Sbjct: 172 PRLVSLRNKVQAIPAISAWI 191 >3KXO-A nrPDB Length = 202 Score = 73.9 bits (180), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 24/203 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+++RG A IR + Y D YE+ + D P+ K L F +P L Sbjct: 9 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 58 Query: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK-- 122 + QS AI Y+ + +L G TE E+ VD + + T+D+ M C+ P EK Sbjct: 59 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-PWAEKKQ 112 Query: 123 -LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD 176 +K + EL P ++ +LG R W GN +T+ DF +F+P LD Sbjct: 113 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD 172 Query: 177 AFPNLKDFISRFEGLEKISAYMK 199 P L + + + ++ ++K Sbjct: 173 NHPRLVTLRKKVQAIPAVANWIK 195 >2AAW-A nrPDB Length = 222 Score = 71.6 bits (174), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 58/210 (27%), Positives = 100/210 (47%), Gaps = 17/210 (8%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTM-GDAPDYDRSQWLNEKFKLGLDFPNLP 61 ++L Y+D RG A IRL+ Y Y +K++ + GDA ++ N K + F +P Sbjct: 16 IVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDA----FVEFKNFKKEKDTPFEQVP 71 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 L G + QS AI+ Y+++K+N+CGE+E + D++ D H + F+ Sbjct: 72 ILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNL---FK 128 Query: 122 KLKPKYL-EELPEKLKLYSEFLGK--------RPWFAGNKITFVDFLVYDVLDLHRIFEP 172 + + +L E+LP+ + + L K + +F GN +T+ D V+++ D P Sbjct: 129 QNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETKYP 188 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSR 202 L FP LK L I Y+ + + Sbjct: 189 SSLKNFPLLKAHNEFISNLPNIKNYITNRK 218 >1M0U-A nrPDB Length = 249 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 52/216 (24%), Positives = 99/216 (45%), Gaps = 33/216 (15%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y++++ LA +R L Y + YE+ + T R +W K + +P L Sbjct: 52 LFYFNVKALAEPLRYLFAYGNQEYEDVRVT--------RDEW--PALKPTMPMGQMPVLE 101 Query: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE--- 121 ++ QS ++ ++A+ LCG T E +++DI+ + D +++ ++ Y PE E Sbjct: 102 VDGKRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDEIKE 161 Query: 122 --------KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD-LHRIFEP 172 ++ P YLE+L + +K L A K+T+ D + D ++ + + Sbjct: 162 KKLVTLNAEVIPFYLEKLEQTVKDNDGHL------ALGKLTWADVYFAGITDYMNYMVKR 215 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 L+ +P L+ + LE I A+++ RPV Sbjct: 216 DLLEPYPALRGVVDAVNALEPIKAWIEK-----RPV 246 >1F3B-A nrPDB Length = 222 Score = 63.2 bits (152), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 28/209 (13%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKL--GLDFPNLP 61 +L Y++ RG IR LL +EEK + +S EK K L F +P Sbjct: 5 VLHYFNARGRMECIRWLLAAAGVEFEEK---------FIQSPEDLEKLKKDGNLMFDQVP 55 Query: 62 YL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNP-- 118 + IDG K+ Q+ AIL YIA K++L G+ +E+ +D+ +D +G + P Sbjct: 56 MVEIDGM-KLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPD 114 Query: 119 --------EFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIF 170 ++ K +YL + LK + + + GN++T VD + +VL F Sbjct: 115 QREAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLEVLLYVEEF 169 Query: 171 EPKCLDAFPNLKDFISRFEGLEKISAYMK 199 + L FP LK F SR L + +++ Sbjct: 170 DASLLTPFPLLKAFKSRISSLPNVKKFLQ 198 >5LCZ-A nrPDB Length = 222 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 58/206 (28%), Positives = 100/206 (48%), Gaps = 24/206 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y++ RG + R LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPEF-- 120 IDG K+ Q+ AIL YIA K+NL G+ +E+ +D+ +D M + ++ P+ Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQRE 118 Query: 121 -------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 ++ K +YL + LK + + + GN++T VD + ++L F+ Sbjct: 119 AKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLELLLYVEEFDAS 173 Query: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 L +FP LK F SR L + +++ Sbjct: 174 LLTSFPLLKAFKSRISSLPNVKKFLQ 199 >1EV4-A nrPDB Length = 221 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 62/217 (28%), Positives = 102/217 (47%), Gaps = 30/217 (13%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKL--GLDFPNLP 61 +L Y++ RG IR LL ++EK + +S EK K L F +P Sbjct: 5 VLHYFNARGRMECIRFLLAAAGVEFDEK---------FIQSPEDLEKLKKDGNLMFDQVP 55 Query: 62 YL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE 119 + IDG K+ Q+ AIL YIA K++L G+ +E+ +D+ +D M + ++ P+ Sbjct: 56 MVEIDGM-KLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPD 114 Query: 120 F---------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIF 170 ++ K +YL + LK + + + GNK+T VD + ++L F Sbjct: 115 QKEAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNKLTRVDIHLLELLLYVEEF 169 Query: 171 EPKCLDAFPNLKDFISRFEGLEKISAYMK--SSRFLP 205 + L +FP LK F SR L + +++ S R LP Sbjct: 170 DASLLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKLP 206 >1B48-A nrPDB Length = 221 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 51/206 (24%), Positives = 93/206 (45%), Gaps = 24/206 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y++ RG +IR LL +EE+ R Q+ + L F +P + Sbjct: 6 LYYFNGRGRMESIRWLLAAAGVEFEEEFLE-------TREQYEKMQKDGHLLFGQVPLVE 58 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMI--------- 114 IDG +TQ+ AIL Y+A K+NL G+ +E++R+D+ + T D M + + Sbjct: 59 IDGMM-LTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKE 117 Query: 115 -CYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 Y+ + K +Y + LK + E + GN++++ D + + + + Sbjct: 118 ESYDLILSRAKTRYFPVFEKILKDHGE-----AFLVGNQLSWADIQLLEAILMVEELSAP 172 Query: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 L FP L+ F +R + I +++ Sbjct: 173 VLSDFPLLQAFKTRISNIPTIKKFLQ 198 >1GSQ-A nrPDB Length = 202 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 59/212 (27%), Positives = 92/212 (43%), Gaps = 25/212 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+ + G A R +L + ++ M D P+ + + N +P L Sbjct: 5 LHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNA----------MPVLD 54 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF--E 121 IDG K++QS I ++AR+ L G+T EK RVD + D + I + PE E Sbjct: 55 IDGT-KMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKE 113 Query: 122 KLKPKYLEELPEKLKLYSEFL-----GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD 176 ++ Y E+ ++L + E L G +F GN +T D Y L++ P+ L Sbjct: 114 AVQQNY-EKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLK 172 Query: 177 AFPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 P + R KI+AY+K RPV Sbjct: 173 DCPKIVALRKRVAECPKIAAYLKK-----RPV 199 >2VCT-A nrPDB Length = 222 Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 59/206 (28%), Positives = 95/206 (46%), Gaps = 24/206 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y +IRG +IR LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE--- 119 IDG K+ Q+ AIL YIA K+NL G+ +EK +D+ D M L + PE Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQD 118 Query: 120 ------FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 EK K +Y + LK + + + GNK++ D + ++L + Sbjct: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 Query: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 + +FP LK +R L + +++ Sbjct: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199 >4Q5F-A nrPDB Length = 218 Score = 57.0 bits (136), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 56/204 (27%), Positives = 84/204 (41%), Gaps = 21/204 (10%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+DIRGL RL+ +E+ + D P K F LP L Sbjct: 18 LTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWP----------ALKPKTPFGQLPLLE 67 Query: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN--PEFEK 122 + QS AI Y+ R+ L G+T E+ +VD + +Q D +L C+ FE+ Sbjct: 68 VDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAEL-RPCFRVLAGFEE 126 Query: 123 L-KPKYLEELP-----EKLKLYSEFLGK--RPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 K K L+E+ + L L +FL K + G +T+ D ++ D L P Sbjct: 127 GDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDF 186 Query: 175 LDAFPNLKDFISRFEGLEKISAYM 198 L LK +I L I ++ Sbjct: 187 LSGHLQLKKYIEHVRELPNIKKWI 210 >2VCV-A nrPDB Length = 222 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 57/206 (27%), Positives = 93/206 (45%), Gaps = 24/206 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y++ RG IR LL +EEK +G A D + + N+ L F +P + Sbjct: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE--- 119 IDG K+ Q+ AIL YIA K+NL G+ +E+ +D+ D N M L + PE Sbjct: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 Query: 120 ------FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 EK K +Y + L+ + + + GNK++ D + ++L + Sbjct: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSS 173 Query: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 + FP LK +R L + +++ Sbjct: 174 LISNFPLLKALKTRISNLPTVKKFLQ 199 >3I6A-A nrPDB Length = 222 Score = 54.3 bits (129), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 54/206 (26%), Positives = 95/206 (46%), Gaps = 24/206 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y++ RG + R LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYFNGRGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPE---- 119 IDG K+ Q+ AIL YIA K+NL G+ +E+ +D+ D + M+ + P Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKD 118 Query: 120 ------FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 EK+K +Y + LK + + + GNK++ D + ++L + Sbjct: 119 AKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 Query: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 + +FP LK +R L + +++ Sbjct: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199 >1ZL9-A nrPDB Length = 207 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 24/213 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y++ RG R + Y YE+ + T + QW K F LP+L Sbjct: 6 LTYFNGRGAGEVSRQIFAYAGQQYEDNRVT--------QEQWPALKETCAAPFGQLPFLE 57 Query: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQL-----GMICYNP- 118 K+ QS+AI ++AR+ L G+T E+ +V+ L +Q D + ++ + P Sbjct: 58 VDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPG 117 Query: 119 EFEKLKPKYLEELPEKLKLYS---EFL--GKRPWFAGNKITFVDFLVYD-VLDLHRIFEP 172 + E LK LP K Y FL + G+ +T++D + DL I + Sbjct: 118 DVETLKKDIF--LPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSADL--IAKG 173 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP 205 FP LK + + + +I ++++ P Sbjct: 174 GDFSKFPELKAHAEKIQAIPQIKKWIETRPVTP 206 >1PL2-A nrPDB Length = 222 Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 94/206 (45%), Gaps = 24/206 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y++ RG + R LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE--- 119 IDG K+ Q AIL YIA K+NL G+ +E+ +D+ D M L + PE Sbjct: 60 IDGM-KLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKD 118 Query: 120 ------FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 EK+K +Y + LK + + + GNK++ D + ++L + Sbjct: 119 AKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 Query: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 + +FP LK +R L + +++ Sbjct: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199 >2WDU-A nrPDB Length = 211 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 66/213 (30%), Positives = 94/213 (44%), Gaps = 22/213 (10%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKL-GLDFPNLPYL 63 L Y+ RG A IRLLL +E+ ++TM QW K L G P L Sbjct: 8 LWYFQFRGRAEPIRLLLTCAGVKFEDYQFTM--------DQWPTIKPTLPGGRVPLLDVT 59 Query: 64 -IDGA-HKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 DG + +S AI +AR+ + GET+EE ++ + + D + ++ I P+ E Sbjct: 60 GPDGKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGE 119 Query: 122 K-LKPKYLEE--LPEKLKLYSEFL----GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 K K K +E P LKL SE L GK AGN+IT D ++ L P Sbjct: 120 KEAKIKEFKENNGPTLLKLVSESLESSGGKH--VAGNRITLGDLFLFTTLTHVMETVPGF 177 Query: 175 LDA-FPNLKDFISRF-EGLEKISAYMKSSRFLP 205 L+ FP L +F ++S Y+K P Sbjct: 178 LEQKFPKLHEFHKSLPTSCSRLSEYLKKRAKTP 210 >1YQ1-A nrPDB Length = 208 Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 53/207 (25%), Positives = 85/207 (41%), Gaps = 26/207 (12%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+ RGL IRLL +EE + PD WL+ K LP L Sbjct: 6 LTYFFFRGLGEPIRLLFHLAGVQFEEVRMN----PD---QTWLD--IKDSTPMKQLPVLN 56 Query: 65 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN------- 117 ++ QS AIL Y+ARK G+T EE+ VD + + D + Sbjct: 57 IDGFELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSA 116 Query: 118 PEFEKLKPKYLEELPEKLKLYSEFLG-----KRPWFAGNKITFVDFLVYD---VLDLHRI 169 E EK + ++ LP + ++ G + G+ ITF D +V D L + + Sbjct: 117 EEVEKFRSEFF--LPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGL 174 Query: 170 FEPKCLDAFPNLKDFISRFEGLEKISA 196 F+ L++ ++ + G+++ A Sbjct: 175 FDESEFTKLAALREKVNSYPGIKEYIA 201 >1U3I-A nrPDB Length = 211 Score = 50.1 bits (118), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 47/171 (27%), Positives = 73/171 (42%), Gaps = 24/171 (14%) Query: 7 YWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDG 66 Y+D RG A +IR+ L YE+++ + D P + G P + D Sbjct: 10 YFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTIP-------GGRLPAVKVTDDH 62 Query: 67 AHK--ITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLK 124 H + +S AI Y+A+KH++ GET+EE V+ L Q D + P+ EK K Sbjct: 63 GHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEK 122 Query: 125 ----------PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD 165 P + E LK + L G+K+T D ++ V+D Sbjct: 123 ITKEILNGKVPVLFNMICESLKGSTGKLA-----VGDKVTLADLVLIAVID 168 >2CA8-A nrPDB Length = 211 Score = 50.1 bits (118), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 50/174 (28%), Positives = 77/174 (44%), Gaps = 30/174 (17%) Query: 7 YWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL-ID 65 Y++ RG A +IR+ L +YE+++ + D P K K + LP + I Sbjct: 10 YFNGRGRAESIRMTLVAAGVNYEDERISFQDWP----------KIKPTIPGGRLPAVKIT 59 Query: 66 GAHK----ITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 H + +S AI Y+A+KH++ G TEEE V+ L Q D + PE E Sbjct: 60 DNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEE 119 Query: 122 KLK----------PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD 165 K K P L+ + E LK + L G+K+T D ++ V+D Sbjct: 120 KQKIIKEILNGKVPVLLDIICESLKASTGKLA-----VGDKVTLADLVLIAVID 168 >1GUL-A nrPDB Length = 222 Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 44/168 (26%), Positives = 74/168 (44%), Gaps = 41/168 (24%) Query: 55 LDFPNLPYL-IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD------- 106 L F +P + IDG K+ Q+ +IL YIA KHNL G+ +E+ +D+ T+D Sbjct: 50 LLFQQVPMVEIDGM-KLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIM 108 Query: 107 --------------NHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK 152 N Q +I Y P FEK+ L+ + + + GN+ Sbjct: 109 HPFLKPDDQQKEVVNMAQKAIIRYFPVFEKI-----------LRGHGQ-----SFLVGNQ 152 Query: 153 ITFVD-FLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMK 199 ++ D L+ +L L P L AFP L+++ + + I +++ Sbjct: 153 LSLADVILLQTILALEEKI-PNILSAFPFLQEYTVKLSNIPTIKRFLE 199 >6F05-A nrPDB Length = 215 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/164 (26%), Positives = 78/164 (47%), Gaps = 25/164 (15%) Query: 57 FPNLPYLIDGAHKITQSNAILCYIARKH-----NLCGETEEEKIRVDI---LENQT---- 104 F +P ++DG +KI +S A++ Y+A K+ +L G+T E++ +V+ +E T Sbjct: 50 FGTVPAVVDGDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPP 109 Query: 105 ---MDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKIT------- 154 + H+ + P EKL + E+L L +Y L K + AG+ ++ Sbjct: 110 LLNLTLHIMFASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAHL 169 Query: 155 -FVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAY 197 F D+LV + + I + K + A+ + D SR E ++ Y Sbjct: 170 PFTDYLVGPIGKAYMIKDRKHVSAWWD--DISSRPAWKETVAKY 211 >1VF1-A nrPDB Length = 229 Score = 43.5 bits (101), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 51/209 (24%), Positives = 87/209 (41%), Gaps = 30/209 (14%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 +L Y++ RG +IR LL +EE R Q+ L F +P + Sbjct: 6 VLYYFNGRGKMESIRWLLAAAGVEFEEVFLE-------TREQYEKLLQSGILMFQQVPMV 58 Query: 64 -IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNP---- 118 IDG K+ Q+ AIL YIA K+NL G+ +E+ +D+ T D +G + P Sbjct: 59 EIDGM-KLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDD---LMGFLLSFPFLSA 114 Query: 119 ---------EFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI 169 EK +Y + LK + + + GN++++ D + + + + Sbjct: 115 EDKVKQCAFVVEKATSRYFPAYEKVLKDHGQ-----DFLVGNRLSWADIHLLEAILMVEE 169 Query: 170 FEPKCLDAFPNLKDFISRFEGLEKISAYM 198 + L FP L+ F R + I ++ Sbjct: 170 KKSDALSGFPLLQAFKKRISSIPTIKKFL 198 >4PNG-A nrPDB Length = 229 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 17/146 (11%) Query: 59 NLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDN--HMQLGMICY 116 +P L D H I S+AI+ Y+ K+ G+T+ + D+L+ +D H + G+I Sbjct: 60 TVPTLEDDGHYIWDSHAIIAYLVSKY---GKTDSLYPK-DLLQRAVVDQRLHFESGVIFA 115 Query: 117 NPEFEKLKPKYL-----------EELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD 165 N KP + + + E +FL + AGN++T DF + + Sbjct: 116 NALRSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVS 175 Query: 166 LHRIFEPKCLDAFPNLKDFISRFEGL 191 +F +P + + R + L Sbjct: 176 SLEVFVKVDTTKYPRIAAWFKRLQKL 201 >5F07-A nrPDB Length = 213 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 21/137 (15%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKH-----NLCGETEEEK 94 D D + +F L F +P + DG K+ +S AI+ Y A K+ NL G T EEK Sbjct: 33 DLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEK 92 Query: 95 IRVDILENQTMDNHMQLGMICYNPEFE-------------KLKPKYLEELPEKLKLYSEF 141 VD N L +N F+ +L Y E+L + L +Y + Sbjct: 93 ALVDQWLEIEAHNFNDL---VFNIVFQVVILPRIGQQGDSELVRTYEEKLEKVLDVYEKR 149 Query: 142 LGKRPWFAGNKITFVDF 158 L K + AG+ T D Sbjct: 150 LSKSKYLAGDSFTLADL 166 >2HNL-A nrPDB Length = 225 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 24/204 (11%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y++ RG A IRLL + SYE+ + T R +W + K F ++P L Sbjct: 30 LTYFNGRGRAEVIRLLFALANVSYEDNRIT--------RDEW--KYLKPRTPFGHVPMLN 79 Query: 65 DGAHKITQSNAI--LCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 + + +S+AI L + EE KI +L +D Q + + + Sbjct: 80 VSGNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVL---NIDELFQKLIPWTHEKNTT 136 Query: 123 LKPKYLEELPEK-----LKLYSEFLGKRPW--FAGNKITFVDFLVYDVLDLHRIFEPKCL 175 K + L E L Y +FL + GNK++ D V+++ L + + L Sbjct: 137 KKAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNM--LMTLDDEVKL 194 Query: 176 DAFPNLKDFISRFEGLEKISAYMK 199 + +P L F+++ + I ++K Sbjct: 195 EEYPQLASFVNKIGQMPGIKEWIK 218 >4MPF-A nrPDB Length = 266 Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust. Identities = 36/151 (23%), Positives = 62/151 (41%), Gaps = 23/151 (15%) Query: 59 NLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNP 118 LP L DG +T+S+AIL Y++ K+ +T + D+ + ++ C Sbjct: 75 KLPTLKDGDFILTESSAILIYLSCKY----QTPDHWYPSDLQARARVHEYLGWHADCIRG 130 Query: 119 EF------EKLKPKYLEELP-EKLK------------LYSEFLGKRPWFAGNKITFVDFL 159 F + L P ++P EK++ L +FLG RP+ AG ++T D + Sbjct: 131 TFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLM 190 Query: 160 VYDVLDLHRIFEPKCLDAFPNLKDFISRFEG 190 + L + + P L + R E Sbjct: 191 ALEELMQPVALGYELFEGRPRLAAWRGRVEA 221 >1N2A-A nrPDB Length = 201 Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 16/87 (18%) Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 E+ KP +L +KL+ +E L W G + T D ++ VL + Sbjct: 119 EEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVLRWAYAVK--------- 169 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRP 207 EGLE I+A+M+ R RP Sbjct: 170 -----LNLEGLEHIAAFMQ--RMAERP 189 >1AW9-A nrPDB Length = 216 Score = 31.2 bits (69), Expect = 0.35, Method: Compositional matrix adjust. Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 28/171 (16%) Query: 57 FPNLPYLIDGAHKITQSNAILCYIARKHN------LCGETEEEKIRV--DILENQTMDNH 108 F +P L+DG + +S AI YIA K+ L K+ V ++ + N Sbjct: 51 FGQIPALVDGDEVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNA 110 Query: 109 MQL-------GMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVD---- 157 L ++ P+ + K+ E+L + L +Y L + + AG++ T D Sbjct: 111 SPLVFQLLVRPLLGGAPDAAVVD-KHAEQLAKVLDVYEAHLARNKYLAGDEFTLADANHA 169 Query: 158 -FLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRP 207 +L+Y L + + + A P++K + +E + A+ K+ +P P Sbjct: 170 SYLLY----LSKTPKAGLVAARPHVKAW---WEAIVARPAFQKTVAAIPLP 213 >3LFL-A nrPDB Length = 240 Score = 30.8 bits (68), Expect = 0.50, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 35/62 (56%), Gaps = 5/62 (8%) Query: 144 KRPWFAGNKITFVDFLV---YDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKS 200 K +F GN I+ +D+L+ ++ L+ ++ E C+D P LK +++ + +SA + S Sbjct: 160 KTTFFGGNSISMIDYLIWPWFERLEAMKLNE--CVDHTPKLKLWMAAMKEDPTVSALLTS 217 Query: 201 SR 202 + Sbjct: 218 EK 219 >1GPI-A nrPDB Length = 431 Score = 30.8 bits (68), Expect = 0.51, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 6 GYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID 65 G + I A+ L T S+ + Y M D Y + LN++F +D NLP ++ Sbjct: 80 GTYGITSTGTALTLKF-VTGSNVGSRVYLMADDTHYQLLKLLNQEFTFDVDMSNLPCGLN 138 Query: 66 GA 67 GA Sbjct: 139 GA 140 >5O3Z-A nrPDB Length = 263 Score = 30.4 bits (67), Expect = 0.58, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 10/80 (12%) Query: 69 KITQSNAILCYIARKHN-------LCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 +I Q N+ + KHN G + + +D+ E + + LG + +P F+ Sbjct: 139 RIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQ 198 Query: 122 KLKPKYLEEL---PEKLKLY 138 L P+Y E+L PE+++ Y Sbjct: 199 SLLPQYAEKLGITPEEVEPY 218 >2C3Q-A nrPDB Length = 247 Score = 30.4 bits (67), Expect = 0.58, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNL 86 D + Q L++ F +P L DG +T+S AIL Y+ RK+ + Sbjct: 41 DLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKV 87 >3R3J-A nrPDB Length = 456 Score = 30.4 bits (67), Expect = 0.61, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 34 TMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILC 78 T + + D ++ K K+ ++ N+P I HK+ Q+N ILC Sbjct: 331 TQNEINENDADLFIQNKCKMIVEGANMPTHIKALHKLKQNNIILC 375 >4RI7-A nrPDB Length = 215 Score = 30.4 bits (67), Expect = 0.65, Method: Compositional matrix adjust. Identities = 27/117 (23%), Positives = 48/117 (41%), Gaps = 17/117 (14%) Query: 57 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICY 116 F +P D + + +S AI YI K+ G + DIL +D ++ + Sbjct: 53 FGQVPAFKDESITLFESRAICRYICDKYADKGN--KSLYGTDILSKANIDQWVETDGQTF 110 Query: 117 NPEF---------------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDF 158 P E L K +++L + L +Y + LG+ + AG++ +F D Sbjct: 111 GPPSGDLVHDLLFSSVPVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADL 167 >4YH2-A nrPDB Length = 222 Score = 30.0 bits (66), Expect = 0.81, Method: Compositional matrix adjust. Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 23/149 (15%) Query: 59 NLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDN--HMQLGMICY 116 +P L D H I S+AI+ Y+ K+ + D L+ +D H + G++ Sbjct: 54 TVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPK----DPLKRAVVDQRLHFESGVVFA 109 Query: 117 N-----------PEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDF-LVYDVL 164 N K+ + + + E FL + + AGN++T DF LV V Sbjct: 110 NGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVA 169 Query: 165 DLHRIFEPKCLDA--FPNLKDFISRFEGL 191 L LD +P + +I + E L Sbjct: 170 SLEAFV---ALDTTKYPRIGAWIKKLEQL 195 >4CHS-A nrPDB Length = 219 Score = 30.0 bits (66), Expect = 0.85, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 129 EELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFE 171 +E E LKL E LG + +F G+ I FVD + +++E Sbjct: 126 KEFIEALKLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKVYE 168 >3VWX-A nrPDB Length = 222 Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust. Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 30/160 (18%) Query: 59 NLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHM--QLGMI-- 114 +P L + H I S+AI+ Y+ K+ ++ D+L+ +D M + G++ Sbjct: 54 TVPTLEEDGHLIWDSHAIMAYLVSKYG----KDDSLYPKDLLKRAVVDQRMYFEAGVLFQ 109 Query: 115 -----CYNPEF----EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD 165 P F ++ ++ + E FL + AG+ +T DF + Sbjct: 110 GGLRNITAPLFFRNQTQIPQHQIDSIVESYGFLESFLKNNKYMAGDHLTIADFSI----- 164 Query: 166 LHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP 205 + L AF + S+F K+SA++KS + LP Sbjct: 165 ---VTSVTSLVAFAEIDQ--SKF---PKLSAWLKSLQSLP 196 >3TOT-A nrPDB Length = 226 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 2/62 (3%) Query: 130 ELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC--LDAFPNLKDFISR 187 ++ E LK S L R W GN +T D V L +P+ + NL F +R Sbjct: 132 KIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQHANLAAFYTR 191 Query: 188 FE 189 E Sbjct: 192 IE 193 >3M8N-A nrPDB Length = 225 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 29/132 (21%), Positives = 55/132 (41%), Gaps = 16/132 (12%) Query: 70 ITQSNAILCYIARKHNLCGET---EEEKIRVDILENQTMDNHMQLG--MICYNPEFEKLK 124 + +SNAIL Y+A +L +T E ++ E ++ ++ +C L+ Sbjct: 66 LAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRDLQ 125 Query: 125 PKYLEELPEK----LKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC---LDA 177 LE+ E+ L++ L +FA ++T D +Y + +C L Sbjct: 126 THALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYG----YTHVADQCDFDLST 181 Query: 178 FPNLKDFISRFE 189 FP + ++ R E Sbjct: 182 FPAVNAWLRRVE 193 >2AYN-A nrPDB Length = 404 Score = 29.3 bits (64), Expect = 1.2, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 3/43 (6%) Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP---RPVFSKM 212 +C+ + P LKD + R+ G + S M S++++ R +F M Sbjct: 31 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM 73 >5GJQ-x nrPDB Length = 494 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 3/43 (6%) Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP---RPVFSKM 212 +C+ + P LKD + R+ G + S M S++++ R +F M Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM 163 >4XEB-A nrPDB Length = 436 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 6 GYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID 65 G + I +++RL T S+ + Y M D Y LN++F +D +LP ++ Sbjct: 80 GTYGITTSGNSLRLNF-VTGSNVGSRTYLMADNTHYQIFDLLNQEFTFTVDVSHLPCGLN 138 Query: 66 GA 67 GA Sbjct: 139 GA 140 >4MDC-A nrPDB Length = 252 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 2/59 (3%) Query: 133 EKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD-LHRIFEPKCLDAFPNLKDFISRFEG 190 + +K S G RPW AG++I++ D + L + E DA P K++ R + Sbjct: 169 QHMKYLSWLAGSRPWLAGDRISYGDLAAAAAISVLDYLGEIDWSDA-PTAKEWYQRLKS 226 >2PBJ-A nrPDB Length = 290 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 6/61 (9%) Query: 122 KLKPKYLEELPEKLKLYSEFLGK-RPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 +L+ E+L E + +GK RP+ G K D VY VL R+ E LDAF + Sbjct: 211 RLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL---RVME--GLDAFDD 265 Query: 181 L 181 L Sbjct: 266 L 266 >3KUK-A nrPDB Length = 309 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 8/52 (15%) Query: 115 CYNPEFEKL--------KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDF 158 C+ PEFE++ E+L ++L S LG+ P GN + +DF Sbjct: 161 CFKPEFEQIVLGKREVRNTDLDEQLVQELARCSAELGEFPTVVGNTMCTLDF 212 >2MMA-A nrPDB Length = 109 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 179 PNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAV 214 P LKD + + EK+ +MK +R P FS V Sbjct: 5 PQLKDTLEKLVNSEKVVLFMKGTRDFPMCGFSNTVV 40 >1JLV-A nrPDB Length = 209 Score = 27.7 bits (60), Expect = 3.9, Method: Compositional matrix adjust. Identities = 23/119 (19%), Positives = 50/119 (42%), Gaps = 11/119 (9%) Query: 60 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMI----- 114 +P L+D + +S AI Y+A K+ + + + + NQ + + +G + Sbjct: 52 IPTLVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRL--YFDMGTLYQRFA 109 Query: 115 -CYNPEFEKLKPKYLE---ELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI 169 Y P+ +P E ++ + + + FL + AG+ +T D V + + + Sbjct: 110 DYYYPQIFAKQPANAENEKKMKDAVDFLNTFLDGHKYVAGDSLTIADLTVLATVSTYDV 168 >2VO4-A nrPDB Length = 219 Score = 27.7 bits (60), Expect = 4.1, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 129 EELPEKLKLYSEFLGKRPWFAGNKITFVDF 158 +E E LKL E LG + +F G+ + FVD Sbjct: 126 KEFIEALKLLEEQLGDKTYFGGDNLGFVDI 155 >4V1Z-A nrPDB Length = 440 Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 4/59 (6%) Query: 13 LAHAIRLLLEYTDSSYEE----KKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGA 67 A L L + +S ++ + Y M D Y+ + LN++F +D NLP ++GA Sbjct: 85 TASGNSLRLNFVTTSQQKNIGSRLYMMKDDSTYEMFKLLNQEFTFDVDVSNLPCGLNGA 143 >5EY6-A nrPDB Length = 217 Score = 27.3 bits (59), Expect = 4.7, Method: Compositional matrix adjust. Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 16/118 (13%) Query: 57 FPNLPYLIDGAHKITQSNAILCYIARKH------NLCGETEEEKIRVDI-LENQTMDNHM 109 F +P D + + +S +I Y+ K+ L G E+ +D +E + Sbjct: 52 FGQVPAFQDESISLFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGP 111 Query: 110 QLGMICYN---------PEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDF 158 G + + P+ + + + E+L + L +Y + LG+ + AG++ TF D Sbjct: 112 SSGALVFQLAFAPRMNIPQDQGVIKQNEEKLGKVLDIYEQRLGESRFLAGDEFTFADL 169 >4HQS-A nrPDB Length = 190 Score = 27.3 bits (59), Expect = 5.5, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 36 GDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCY 79 G+ + D W GLD+ NLP L+D + K+ ++ + Y Sbjct: 119 GEQSEADFKNWYK-----GLDYKNLPVLVDPSGKLLETYGVRSY 157 >4EVM-A nrPDB Length = 138 Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 36 GDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCY 79 G+ + D W GLD+ NLP L+D + K+ ++ + Y Sbjct: 67 GEQSEADFKNWYK-----GLDYKNLPVLVDPSGKLLETYGVRSY 105 >4YDH-A nrPDB Length = 433 Score = 26.6 bits (57), Expect = 8.9, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 2/53 (3%) Query: 90 TEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFL 142 TE +K++V I +DN +G + + E + +++EEL E++ L +E L Sbjct: 340 TESDKLQVQI--QAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERL 390 >1PN9-A nrPDB Length = 209 Score = 26.6 bits (57), Expect = 9.0, Method: Compositional matrix adjust. Identities = 28/141 (19%), Positives = 60/141 (42%), Gaps = 20/141 (14%) Query: 60 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMIC---- 115 +P L+D + +S AI Y+A K+ + + + + NQ + + +G + Sbjct: 52 IPTLVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRL--YFDMGTLYQRFA 109 Query: 116 ---YNPEFEK--LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI- 169 Y F K P+ +++ + + + FL + + AGN +T D + + + + Sbjct: 110 DYHYPQIFAKQPANPENEKKMKDAVGFLNTFLEGQEYAAGNDLTIADLSLAATIATYEVA 169 Query: 170 ---FEPKCLDAFPNLKDFISR 187 F P +PN+ + +R Sbjct: 170 GFDFAP-----YPNVAAWFAR 185 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1XWK-A nrPDB 325 8e-90 2DC5-A nrPDB 316 6e-87 4GTU-A nrPDB 315 1e-86 1HNA-A nrPDB 311 2e-85 1B4P-A nrPDB 308 2e-84 5FWG-A nrPDB 307 3e-84 3GTU-B nrPDB 304 2e-83 1GSU-A nrPDB 279 5e-76 2FHE-A nrPDB 271 2e-73 5AN1-A nrPDB 261 2e-70 2WRT-A nrPDB 258 1e-69 4Q5Q-A nrPDB 254 2e-68 1FHE-A nrPDB 247 3e-66 1B8X-A nrPDB 240 4e-64 1BG5-A nrPDB 239 5e-64 2GSR-A nrPDB 238 1e-63 1DUG-A nrPDB 237 2e-63 2GLR-A nrPDB 237 3e-63 5D73-A nrPDB 230 4e-61 4WR5-A nrPDB 228 1e-60 18GS-A nrPDB 226 5e-60 1TU7-A nrPDB 215 1e-56 1F3B-A nrPDB 209 6e-55 1B48-A nrPDB 203 6e-53 3KXO-A nrPDB 202 7e-53 2VCV-A nrPDB 202 8e-53 3I6A-A nrPDB 202 9e-53 1VF1-A nrPDB 198 1e-51 5Y9Z-A nrPDB 197 3e-51 2VCT-A nrPDB 197 4e-51 1PL2-A nrPDB 196 6e-51 1EV4-A nrPDB 195 1e-50 5LCZ-A nrPDB 192 7e-50 2AAW-A nrPDB 191 2e-49 4Q5F-A nrPDB 187 3e-48 1GSQ-A nrPDB 187 4e-48 1ZL9-A nrPDB 185 2e-47 1M0U-A nrPDB 178 1e-45 1GUL-A nrPDB 175 1e-44 2WDU-A nrPDB 170 4e-43 1U3I-A nrPDB 168 1e-42 2CA8-A nrPDB 167 5e-42 1YQ1-A nrPDB 157 4e-39 6F05-A nrPDB 114 3e-26 5F07-A nrPDB 113 8e-26 4PNG-A nrPDB 110 6e-25 Sequences not found previously or not previously below threshold: 4Q5R-A nrPDB 154 2e-38 2HNL-A nrPDB 119 8e-28 4YH2-A nrPDB 95 2e-20 1AXD-A nrPDB 92 3e-19 5EY6-A nrPDB 89 2e-18 3VWX-A nrPDB 85 2e-17 4RI7-A nrPDB 85 2e-17 5F06-A nrPDB 83 8e-17 1AW9-A nrPDB 77 6e-15 5A5K-A nrPDB 75 2e-14 5ZWP-A nrPDB 74 4e-14 3LSZ-A nrPDB 72 1e-13 1PN9-A nrPDB 72 1e-13 2C3Q-A nrPDB 71 3e-13 4MPF-A nrPDB 71 5e-13 2IL3-A nrPDB 70 1e-12 1JLV-A nrPDB 68 3e-12 5F0G-A nrPDB 68 3e-12 2GDR-A nrPDB 67 7e-12 5F05-A nrPDB 66 1e-11 2CZ2-A nrPDB 66 1e-11 3UAR-A nrPDB 66 1e-11 3M3M-A nrPDB 66 1e-11 3MAK-A nrPDB 66 1e-11 1V2A-A nrPDB 65 3e-11 1FW1-A nrPDB 64 6e-11 1F2E-A nrPDB 62 2e-10 3M8N-A nrPDB 62 2e-10 3LFL-A nrPDB 60 8e-10 3IBH-A nrPDB 60 1e-09 3TOT-A nrPDB 58 3e-09 4IKH-A nrPDB 58 3e-09 3GH6-A nrPDB 57 5e-09 2PVQ-A nrPDB 55 2e-08 4MDC-A nrPDB 55 4e-08 2PMT-A nrPDB 54 5e-08 3UBL-A nrPDB 54 6e-08 4CHS-A nrPDB 53 7e-08 5F8B-A nrPDB 53 1e-07 5J5N-A nrPDB 51 3e-07 2VO4-A nrPDB 51 3e-07 4FQU-A nrPDB 50 7e-07 1E6B-A nrPDB 50 9e-07 4J2F-A nrPDB 49 2e-06 4PXO-A nrPDB 49 2e-06 3PR8-A nrPDB 48 2e-06 3GX0-A nrPDB 48 2e-06 1N2A-A nrPDB 48 3e-06 4G0L-A nrPDB 48 3e-06 4BVY-B nrPDB 47 5e-06 5LOL-A nrPDB 47 7e-06 3PPU-A nrPDB 46 1e-05 3C8E-A nrPDB 46 1e-05 5NR1-A nrPDB 46 1e-05 3QAG-A nrPDB 46 1e-05 5ECL-B nrPDB 45 3e-05 4QQ7-A nrPDB 44 5e-05 2JL4-A nrPDB 43 7e-05 5ELG-A nrPDB 43 8e-05 6GCB-A nrPDB 43 9e-05 4USS-A nrPDB 43 1e-04 4IGJ-A nrPDB 43 1e-04 6GZF-A nrPDB 41 3e-04 6GC9-A nrPDB 41 3e-04 6EP7-A nrPDB 40 6e-04 4PTS-A nrPDB 40 8e-04 5N9U-A nrPDB 38 0.003 3RBT-A nrPDB 38 0.004 3M1G-A nrPDB 37 0.006 1G6W-A nrPDB 37 0.007 3IR4-A nrPDB 36 0.012 6JWK-A nrPDB 34 0.043 4PQI-A nrPDB 33 0.12 3BBY-A nrPDB 32 0.21 1G7O-A nrPDB 32 0.24 3NIV-A nrPDB 31 0.35 1GWC-A nrPDB 31 0.40 5HSX-A nrPDB 30 0.91 5JMV-A nrPDB 30 1.1 2IWR-A nrPDB 30 1.1 6AIY-A nrPDB 30 1.1 3FQJ-A nrPDB 29 1.3 5KEU-A nrPDB 29 1.3 2JZR-A nrPDB 29 1.4 4D9F-A nrPDB 29 1.7 4K0G-A nrPDB 29 1.8 4CZI-A nrPDB 28 2.4 5LKB-A nrPDB 28 2.6 4J15-A nrPDB 28 2.6 3ENH-A nrPDB 28 2.8 5KOD-A nrPDB 28 3.0 2YV7-A nrPDB 28 3.1 2PAR-A nrPDB 28 3.4 3LG6-A nrPDB 28 3.5 5TDL-A nrPDB 28 3.8 5R1R-A nrPDB 27 5.2 2OBA-A nrPDB 27 5.4 3ADR-A nrPDB 27 5.8 3R2G-A nrPDB 27 6.3 3AGR-A nrPDB 27 6.5 5E1J-A nrPDB 27 6.8 5Y7I-A nrPDB 27 7.3 4G74-A nrPDB 27 7.4 2RAS-A nrPDB 27 7.8 >1XWK-A nrPDB Length = 218 Score = 325 bits (834), Expect = 8e-90, Method: Composition-based stats. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL Sbjct: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF Sbjct: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >2DC5-A nrPDB Length = 231 Score = 316 bits (809), Expect = 6e-87, Method: Composition-based stats. Identities = 177/217 (81%), Positives = 199/217 (91%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPM LGYWDIRGLAHAIRL LEYTDSSYEEK+YTMGDAPDYD+SQWLNEKFKLGLDFPNL Sbjct: 8 MPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNL 67 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PYLIDG+HKITQSNAIL Y+ RKHNLCGETEEE+IRVDILENQ MDN M L +CYN +F Sbjct: 68 PYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADF 127 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 EKLKP YLE+LP ++LYSEFLGKRPWFAG+KITFVDF+ YDVL+ +++FE KCLDAFPN Sbjct: 128 EKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPN 187 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 LKDFI+RFEGL+KIS YMK+SRFLPRP+F+KMA WG+ Sbjct: 188 LKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGS 224 >4GTU-A nrPDB Length = 217 Score = 315 bits (807), Expect = 1e-86, Method: Composition-based stats. Identities = 188/217 (86%), Positives = 203/217 (93%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 M LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 SMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQ MD QL +CY+P+FE Sbjct: 61 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFE 120 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 KLKP+YLEELP ++ +S+FLGKRPWF G+KITFVDFL YDVLDLHRIFEP CLDAFPNL Sbjct: 121 KLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNL 180 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 KDFISRFEGLEKISAYMKSSRFLP+P+++++AVWGNK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >1HNA-A nrPDB Length = 217 Score = 311 bits (797), Expect = 2e-85, Method: Composition-based stats. Identities = 182/217 (83%), Positives = 203/217 (93%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PM LGYW+IRGLAH+IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YLIDG HKITQSNAIL YIARKHNLCGE+E+E+IR DILENQ MD+ MQL +CY+P+FE Sbjct: 61 YLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFE 120 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 KLKP+YL+ LPE LKLYS+FLGK+PWF G+KITFVDF+ YDVL+ +++FEP CLDAFPNL Sbjct: 121 KLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNL 180 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 KDFISRFEGLEKISAYMKSSRFLPRPVF+KMAV+GNK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >1B4P-A nrPDB Length = 217 Score = 308 bits (788), Expect = 2e-84, Method: Composition-based stats. Identities = 175/217 (80%), Positives = 199/217 (91%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YLIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IRVD+LENQ MD +QL M+CY+P+FE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFE 120 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 + KP+YLE LPEK+KLYSEFLGK+PWFAGNKIT+VDFLVYDVLD HRIFEPKCLDAFPNL Sbjct: 121 RKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNL 180 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 KDF++RFEGL+KIS YMKS RFL +P+F+KMA W K Sbjct: 181 KDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >5FWG-A nrPDB Length = 217 Score = 307 bits (786), Expect = 3e-84, Method: Composition-based stats. Identities = 172/217 (79%), Positives = 199/217 (91%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YLIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IR DI+ENQ MDN MQL M+CYNP+FE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 120 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 K KP++L+ +PEK+KLYSEFLGKRPWFAG+K+T+VDFL YD+LD + IFEPKCLDAFPNL Sbjct: 121 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 180 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 KDF++RFEGL+KISAYMKSSR+L P+FSK+A W NK Sbjct: 181 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >3GTU-B nrPDB Length = 224 Score = 304 bits (779), Expect = 2e-83, Method: Composition-based stats. Identities = 158/217 (72%), Positives = 185/217 (85%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 M+LGYWDIRGLAHAIRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLP Sbjct: 5 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 64 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 YL+DG +KITQSNAIL YIARKHN+CGETEEEKIRVDI+ENQ MD QL +CY+ + E Sbjct: 65 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 124 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 KLKP+YLEELP +LK +S FLGK WFAG K+TFVDFL YD+LD +RIF+PKCLD FPNL Sbjct: 125 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 184 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 K F+ RFE LEKI+AY++S +F P+ +KMA WGNK Sbjct: 185 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >1GSU-A nrPDB Length = 219 Score = 279 bits (715), Expect = 5e-76, Method: Composition-based stats. Identities = 142/216 (65%), Positives = 166/216 (76%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 + LGYWDIRGLAHAIRLLLEYT++ Y+E++Y G APD+D S W NEK KLGLDFPNLPY Sbjct: 2 VTLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPY 61 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 LIDG K+TQSNAIL YIARKHN+CGETE EK RVD+LEN MD M +CY+P+FEK Sbjct: 62 LIDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEK 121 Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182 LKP YLE+LP KL+ S FLG R WF G+K+TFVDFL YDVLD R+F P C + NL Sbjct: 122 LKPAYLEQLPGKLRQLSRFLGSRSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQGNLS 181 Query: 183 DFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 F+ RFE LEKISAYM+S RF+ P+F A+W NK Sbjct: 182 QFLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >2FHE-A nrPDB Length = 216 Score = 271 bits (692), Expect = 2e-73, Method: Composition-based stats. Identities = 105/216 (48%), Positives = 138/216 (63%), Gaps = 5/216 (2%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW IRGL +RLLLEY YEE+ Y D +W ++KF+LGLD PNLP Sbjct: 1 PAKLGYWKIRGLQQPVRLLLEYLGEKYEEQIYERDDG-----EKWFSKKFELGLDLPNLP 55 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 Y ID K+TQS AIL YIA KH + G T EE+ RV ++E +D + I Y P+FE Sbjct: 56 YYIDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFE 115 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 +LK YL++LP +K++S+FLGK P+ G ++ VDF+VY+ LD R EP CLD FPNL Sbjct: 116 QLKEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNL 175 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 + F+SR E L I AYM+S+RF+ P+ A +G Sbjct: 176 QQFMSRIEALPSIKAYMESNRFIKWPLNGWHAQFGG 211 >5AN1-A nrPDB Length = 219 Score = 261 bits (666), Expect = 2e-70, Method: Composition-based stats. Identities = 114/215 (53%), Positives = 143/215 (66%), Gaps = 2/215 (0%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M +LGYW R L IRL+L YT + +EEK Y +GDAPDYD+S+WL KFKLGL FPNL Sbjct: 1 MLPVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNL 60 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PY IDG KITQS AI+ Y+ARKH LCG T EE +R D++E Q D H + Y E Sbjct: 61 PYYIDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTY--EH 118 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 + K Y LP KL+ YS+FLG RPWFAG+K+T++DFL Y++ D H + CLD F N Sbjct: 119 YEQKDAYTASLPAKLRQYSDFLGSRPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDGFKN 178 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVW 215 L+ F RFE LE I YM S +FL +P+ +K A + Sbjct: 179 LQAFQKRFEDLEAIKKYMASPKFLKKPICNKYAQF 213 >2WRT-A nrPDB Length = 218 Score = 258 bits (660), Expect = 1e-69, Method: Composition-based stats. Identities = 107/217 (49%), Positives = 140/217 (64%), Gaps = 5/217 (2%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MP LGYW IRGL +RLLLEY YEE Y D R +WL +KF +GLD PNL Sbjct: 1 MPAKLGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRDD-----REKWLGDKFNMGLDLPNL 55 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PY ID K+TQS AI+ YIA KH + G T EE+ R+ ++E MD M +CYNP+F Sbjct: 56 PYYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCYNPKF 115 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 E++K YL+ELP LK++S FLG R + G+ ++ VDF+VY+ LD R P+CL+ FP Sbjct: 116 EEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPK 175 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 LK+F SR E L KI AYM+S +F+ P+ S +A +G Sbjct: 176 LKEFKSRIEDLPKIKAYMESEKFIKWPLNSWIASFGG 212 >4Q5Q-A nrPDB Length = 219 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 99/214 (46%), Positives = 140/214 (65%), Gaps = 2/214 (0%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 ILGYWDIRG A IRLLL Y+ + +K+Y +G APD+DRS+WLNEKF LGLDFPNLPY Sbjct: 4 PILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPY 63 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 IDG K+TQ+ AIL Y+ RK+ L G + E+IR+ + E QT D + +CY+ +K Sbjct: 64 YIDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANCDK 123 Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182 LKP YL+ LP+ LKL S+F+G+ + AG I++VDF +Y+ L ++ P+ F NLK Sbjct: 124 LKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVPEVFGQFENLK 183 Query: 183 DFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWG 216 ++ R E L ++S Y+K + P+ + + W Sbjct: 184 RYVERMESLPRVSDYIKKQQ--PKTFNAPTSKWN 215 >1FHE-A nrPDB Length = 217 Score = 247 bits (630), Expect = 3e-66, Method: Composition-based stats. Identities = 104/215 (48%), Positives = 141/215 (65%), Gaps = 5/215 (2%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW +RGLA +RL LEY YEE Y D R +W++EKF +GLD PNLP Sbjct: 1 PAKLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDD-----REKWMSEKFNMGLDLPNLP 55 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 Y ID K+TQS AI+ YIA KH + G T EE+ R+ ++E MD + G +CYNP+FE Sbjct: 56 YYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNPKFE 115 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 ++K +Y++ELP+ LK++S+FLG R + G+ ++ VDF++Y+ LD R P CLD FP L Sbjct: 116 EVKEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPKL 175 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWG 216 K+F SR E L KI AYM+S RF+ P+ A +G Sbjct: 176 KEFKSRIEALPKIKAYMESKRFIKWPLNGWAASFG 210 >1B8X-A nrPDB Length = 280 Score = 240 bits (612), Expect = 4e-64, Method: Composition-based stats. Identities = 91/216 (42%), Positives = 130/216 (60%), Gaps = 5/216 (2%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 ILGYW I+GL RLLLEY + YEE Y + +W N+KF+LGL+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 Y IDG K+TQS AI+ YIA KHN+ G +E+ + +LE +D + I Y+ +FE Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 LK +L +LPE LK++ + L + + G+ +T DF++YD LD+ +P CLDAFP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 F R E + +I Y+KSS+++ P+ A +G Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >1BG5-A nrPDB Length = 254 Score = 239 bits (611), Expect = 5e-64, Method: Composition-based stats. Identities = 92/217 (42%), Positives = 131/217 (60%), Gaps = 5/217 (2%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M ILGYW I+GL RLLLEY + YEE Y + +W N+KF+LGL+FPNL Sbjct: 1 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNL 55 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 PY IDG K+TQS AI+ YIA KHN+ G +E+ + +LE +D + I Y+ +F Sbjct: 56 PYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDF 115 Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 E LK +L +LPE LK++ + L + + G+ +T DF++YD LD+ +P CLDAFP Sbjct: 116 ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 175 Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 L F R E + +I Y+KSS+++ P+ A +G Sbjct: 176 LVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 212 >2GSR-A nrPDB Length = 207 Score = 238 bits (608), Expect = 1e-63, Method: Composition-based stats. Identities = 68/213 (31%), Positives = 109/213 (51%), Gaps = 15/213 (7%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ +RG A+R+LL D S++E+ TM P K F LP Sbjct: 2 PYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTMETWP----------PLKPSCLFRQLP 51 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 DG + QSNAIL ++ R L G+ ++E VD++ + D + + Y +E Sbjct: 52 KFQDGDLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYT-NYE 110 Query: 122 KLKPKYLEELPEKLKLYSEFL----GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDA 177 K KY++ELPE LK + L G + + G++I+F D+ + D+L +H++ P CLDA Sbjct: 111 AGKEKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDA 170 Query: 178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPVFS 210 FP L +++R KI A++ S + RP+ Sbjct: 171 FPLLSAYVARLSARPKIKAFLASPEHVNRPING 203 >1DUG-A nrPDB Length = 234 Score = 237 bits (606), Expect = 2e-63, Method: Composition-based stats. Identities = 91/216 (42%), Positives = 130/216 (60%), Gaps = 5/216 (2%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 ILGYW I+GL RLLLEY + YEE Y + +W N+KF+LGL+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 Y IDG K+TQS AI+ YIA KHN+ G +E+ + +LE +D + I Y+ +FE Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 LK +L +LPE LK++ + L + + G+ +T DF++YD LD+ +P CLDAFP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 F R E + +I Y+KSS+++ P+ A +G Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >2GLR-A nrPDB Length = 209 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 60/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ +RG A+R+LL S++E+ T+ W+ K + LP Sbjct: 2 PYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTI--------DTWMQGLLKPTCLYGQLP 53 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 DG + QSNAIL ++ R L G+ + E ++D++ + D + + Y +E Sbjct: 54 KFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYT-NYE 112 Query: 122 KLKPKYLEELPEKLKLYSEFL----GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDA 177 K Y++ LP LK + L G + + G++I+F D+ + D+L +H++ P CLD Sbjct: 113 NGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDN 172 Query: 178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPVFS 210 FP L +++R KI A++ S + RP+ Sbjct: 173 FPLLSAYVARLSARPKIKAFLSSPEHVNRPING 205 >5D73-A nrPDB Length = 208 Score = 230 bits (587), Expect = 4e-61, Method: Composition-based stats. Identities = 72/215 (33%), Positives = 104/215 (48%), Gaps = 16/215 (7%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+ IRGLA IRL+L + + + D P K F L Sbjct: 1 MSYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWP----------SMKSHFHFGQL 50 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 P L DG H+I QS AIL ++ARKHNL G E E +D+ D H + + Y + Sbjct: 51 PCLYDGDHQIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQA-Y 109 Query: 121 EKLKPKYLEE-LPEKLKLYSEFLGKRP----WFAGNKITFVDFLVYDVLDLHRIFEPKCL 175 + K Y+++ LP +L + + L R + G KI++VDF++++ LD+H+I +P CL Sbjct: 110 DTEKDSYIKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCL 169 Query: 176 DAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFS 210 D FP LK + R E + Y K PV Sbjct: 170 DKFPLLKAYHQRMEDRPGLKEYCKQRNRAKIPVNG 204 >4WR5-A nrPDB Length = 244 Score = 228 bits (582), Expect = 1e-60, Method: Composition-based stats. Identities = 88/216 (40%), Positives = 126/216 (58%), Gaps = 5/216 (2%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 ILGYW I+GL RLLLE + YEE + +W N+KF+LGL+FPNLP Sbjct: 26 SPILGYWKIKGLVQPTRLLLEXLEEKYEEHLXERDEG-----DKWRNKKFELGLEFPNLP 80 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 Y IDG K+TQS AI+ IA KHN+ G +E+ + +LE +D + I Y+ +FE Sbjct: 81 YXIDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 140 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 LK +L +LPE LK++ + L + G+ +T DF++YD LD+ +P CLDAFP L Sbjct: 141 TLKVDFLSKLPEMLKMFEDRLCHKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAFPKL 200 Query: 182 KDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGN 217 F R E + +I Y+KSS+++ P+ A +G Sbjct: 201 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 236 >18GS-A nrPDB Length = 210 Score = 226 bits (577), Expect = 5e-60, Method: Composition-based stats. Identities = 59/213 (27%), Positives = 103/213 (48%), Gaps = 13/213 (6%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ +RG A+R+LL S++E+ T+ W K + LP Sbjct: 3 PYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLP 54 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 DG + QSN IL ++ R L G+ ++E VD++ + D + + Y +E Sbjct: 55 KFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYE 113 Query: 122 KLKPKYLEELPEKLKLYSEFL----GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDA 177 K Y++ LP +LK + L G + + G++I+F D+ + D+L +H + P CLDA Sbjct: 114 AGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDA 173 Query: 178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPVFS 210 FP L ++ R K+ A++ S ++ P+ Sbjct: 174 FPLLSAYVGRLSARPKLKAFLASPEYVNLPING 206 >1TU7-A nrPDB Length = 208 Score = 215 bits (548), Expect = 1e-56, Method: Composition-based stats. Identities = 70/215 (32%), Positives = 102/215 (47%), Gaps = 16/215 (7%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+ IRGLA IRL L D + + + D K F L Sbjct: 1 MSYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRIAKDDF----------SSIKSQFQFGQL 50 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 P L DG +I QS AIL ++ARK+NL GE E E +D+ D H++ + Y + Sbjct: 51 PCLYDGDQQIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMA-Y 109 Query: 121 EKLKPKYLEE-LPEKLKLYSEFLG----KRPWFAGNKITFVDFLVYDVLDLHRIFEPKCL 175 E K Y++ LP +L + + L R G+KI++ D+ +++ LD+H+I +P CL Sbjct: 110 ETEKDPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCL 169 Query: 176 DAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFS 210 D FP LK F R + K+ Y + PV Sbjct: 170 DKFPLLKVFHQRMKDRPKLKEYCEKRDAAKVPVNG 204 >1F3B-A nrPDB Length = 222 Score = 209 bits (533), Expect = 6e-55, Method: Composition-based stats. Identities = 55/222 (24%), Positives = 91/222 (40%), Gaps = 22/222 (9%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 +L Y++ RG IR LL +EEK K L F +P Sbjct: 4 PVLHYFNARGRMECIRWLLAAAGVEFEEKFIQ-------SPEDLEKLKKDGNLMFDQVPM 56 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF-- 120 + K+ Q+ AIL YIA K++L G+ +E+ +D+ +D +G + P Sbjct: 57 VEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQR 116 Query: 121 --------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 ++ K +YL + LK + + + GN++T VD + +VL F+ Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLEVLLYVEEFDA 171 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAV 214 L FP LK F SR L + +++ P+ +K Sbjct: 172 SLLTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQ 213 >1B48-A nrPDB Length = 221 Score = 203 bits (516), Expect = 6e-53, Method: Composition-based stats. Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 22/220 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y++ RG +IR LL +EE+ R Q+ + L F +P Sbjct: 4 PKLYYFNGRGRMESIRWLLAAAGVEFEEEFLE-------TREQYEKMQKDGHLLFGQVPL 56 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 + +TQ+ AIL Y+A K+NL G+ +E++R+D+ + T D M + + + EK Sbjct: 57 VEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEK 116 Query: 123 ----------LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 K +Y + LK + E + GN++++ D + + + + Sbjct: 117 EESYDLILSRAKTRYFPVFEKILKDHGE-----AFLVGNQLSWADIQLLEAILMVEELSA 171 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKM 212 L FP L+ F +R + I +++ P Sbjct: 172 PVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPY 211 >3KXO-A nrPDB Length = 202 Score = 202 bits (515), Expect = 7e-53, Method: Composition-based stats. Identities = 53/211 (25%), Positives = 87/211 (41%), Gaps = 19/211 (9%) Query: 1 MP-MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN 59 MP L Y+++RG A IR + Y D YE+ + D P+ K L F Sbjct: 4 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK 53 Query: 60 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPE 119 +P L + QS AI Y+ + +L G TE E+ VD + + D + + Sbjct: 54 IPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCF---PWAEK 110 Query: 120 FEKLKPKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 + +K + EL P ++ +LG R W GN +T+ DF +F+P Sbjct: 111 KQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDL 170 Query: 175 LDAFPNLKDFISRFEGLEKISAYMKSSRFLP 205 LD P L + + + ++ ++K Sbjct: 171 LDNHPRLVTLRKKVQAIPAVANWIKRRPQTK 201 >2VCV-A nrPDB Length = 222 Score = 202 bits (515), Expect = 8e-53, Method: Composition-based stats. Identities = 54/219 (24%), Positives = 89/219 (40%), Gaps = 22/219 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y++ RG IR LL +EEK G A D + + L F +P Sbjct: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKFI--GSAEDLGKLRND-----GSLMFQQVPM 57 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDN-HMQLGMICYNPEF- 120 + K+ Q+ AIL YIA K+NL G+ +E+ +D+ D M L + PE Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEK 117 Query: 121 --------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 EK K +Y + L+ + + + GNK++ D + ++L + Sbjct: 118 DAKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDS 172 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSK 211 + FP LK +R L + +++ P +K Sbjct: 173 SLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAK 211 >3I6A-A nrPDB Length = 222 Score = 202 bits (514), Expect = 9e-53, Method: Composition-based stats. Identities = 50/215 (23%), Positives = 88/215 (40%), Gaps = 22/215 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y++ RG + R LL +EEK + D R+ L F +P Sbjct: 5 PKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRN-------DGYLMFQQVPM 57 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF-- 120 + K+ Q+ AIL YIA K+NL G+ +E+ +D+ D + M+ + P Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEK 117 Query: 121 --------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 EK+K +Y + LK + + + GNK++ D + ++L + Sbjct: 118 DAKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDS 172 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRP 207 + +FP LK +R L + +++ P Sbjct: 173 SLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 >1VF1-A nrPDB Length = 229 Score = 198 bits (504), Expect = 1e-51, Method: Composition-based stats. Identities = 47/207 (22%), Positives = 84/207 (40%), Gaps = 22/207 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 +L Y++ RG +IR LL +EE R Q+ L F +P Sbjct: 5 PVLYYFNGRGKMESIRWLLAAAGVEFEEVFLE-------TREQYEKLLQSGILMFQQVPM 57 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 + K+ Q+ AIL YIA K+NL G+ +E+ +D+ T D L + +K Sbjct: 58 VEIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDK 117 Query: 123 LK----------PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 +K +Y + LK + + + GN++++ D + + + + + Sbjct: 118 VKQCAFVVEKATSRYFPAYEKVLKDHGQ-----DFLVGNRLSWADIHLLEAILMVEEKKS 172 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMK 199 L FP L+ F R + I ++ Sbjct: 173 DALSGFPLLQAFKKRISSIPTIKKFLA 199 >5Y9Z-A nrPDB Length = 199 Score = 197 bits (501), Expect = 3e-51, Method: Composition-based stats. Identities = 57/211 (27%), Positives = 90/211 (42%), Gaps = 19/211 (9%) Query: 1 MP-MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN 59 MP L Y+++RG A IR + Y D YE+ + D P K K L F Sbjct: 1 MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWP----------KIKPTLPFGK 50 Query: 60 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPE 119 +P L + QS AI Y+ + +L G+TE E+ +VD + + D + E Sbjct: 51 IPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLF---PWAEE 107 Query: 120 FEKLKPKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 + LK + +L P LK +LG + WF GN +T+ DF + +P Sbjct: 108 NQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDL 167 Query: 175 LDAFPNLKDFISRFEGLEKISAYMKSSRFLP 205 L +P L ++ + + ISA++ Sbjct: 168 LGIYPRLVSLRNKVQAIPAISAWILKRPQTK 198 >2VCT-A nrPDB Length = 222 Score = 197 bits (500), Expect = 4e-51, Method: Composition-based stats. Identities = 54/219 (24%), Positives = 91/219 (41%), Gaps = 22/219 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y +IRG +IR LL +EEK + D R+ L F +P Sbjct: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRN-------DGYLMFQQVPM 57 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN-PEF- 120 + K+ Q+ AIL YIA K+NL G+ +EK +D+ D + ++ + PE Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQ 117 Query: 121 --------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 EK K +Y + LK + + + GNK++ D + ++L + Sbjct: 118 DAKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDS 172 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSK 211 + +FP LK +R L + +++ P+ K Sbjct: 173 SLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEK 211 >1PL2-A nrPDB Length = 222 Score = 196 bits (499), Expect = 6e-51, Method: Composition-based stats. Identities = 50/219 (22%), Positives = 88/219 (40%), Gaps = 22/219 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y++ RG + R LL +EEK + D R+ L F +P Sbjct: 5 PKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRN-------DGYLMFQQVPM 57 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF-- 120 + K+ Q AIL YIA K+NL G+ +E+ +D+ D + ++ P Sbjct: 58 VEIDGMKLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEK 117 Query: 121 --------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 EK+K +Y + LK + + + GNK++ D + ++L + Sbjct: 118 DAKLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDS 172 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSK 211 + +FP LK +R L + +++ P+ K Sbjct: 173 SLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEK 211 >1EV4-A nrPDB Length = 221 Score = 195 bits (496), Expect = 1e-50, Method: Composition-based stats. Identities = 54/220 (24%), Positives = 91/220 (41%), Gaps = 22/220 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 +L Y++ RG IR LL ++EK K L F +P Sbjct: 4 PVLHYFNARGRMECIRFLLAAAGVEFDEKFIQ-------SPEDLEKLKKDGNLMFDQVPM 56 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 + K+ Q+ AIL YIA K++L G+ +E+ +D+ +D + + P +K Sbjct: 57 VEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQK 116 Query: 123 ----------LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 K +YL + LK + + + GNK+T VD + ++L F+ Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNKLTRVDIHLLELLLYVEEFDA 171 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKM 212 L +FP LK F SR L + +++ P+ +K Sbjct: 172 SLLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKLPMDAKQ 211 >5LCZ-A nrPDB Length = 222 Score = 192 bits (489), Expect = 7e-50, Method: Composition-based stats. Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 22/220 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y++ RG + R LL +EEK + D R+ L F +P Sbjct: 5 PKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRN-------DGYLMFQQVPM 57 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF-- 120 + K+ Q+ AIL YIA K+NL G+ +E+ +D+ +D + + P Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQR 117 Query: 121 --------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 ++ K +YL + LK + + + GN++T VD + ++L F+ Sbjct: 118 EAKTALAKDRTKNRYLPAFEKVLKSHGQ-----DYLVGNRLTRVDIHLLELLLYVEEFDA 172 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKM 212 L +FP LK F SR L + +++ + +K Sbjct: 173 SLLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQ 212 >2AAW-A nrPDB Length = 222 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 54/208 (25%), Positives = 93/208 (44%), Gaps = 13/208 (6%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 ++L Y+D RG A IRL+ Y Y +K++ + ++ N K + F +P Sbjct: 16 IVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVN---GDAFVEFKNFKKEKDTPFEQVPI 72 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 L G + QS AI+ Y+++K+N+CGE+E + D++ D H + + E Sbjct: 73 LQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNET 132 Query: 123 LKPKYLEELPEKLKLYSEFLGK--------RPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 E+LP+ + + L K + +F GN +T+ D V+++ D P Sbjct: 133 T--FLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETKYPSS 190 Query: 175 LDAFPNLKDFISRFEGLEKISAYMKSSR 202 L FP LK L I Y+ + + Sbjct: 191 LKNFPLLKAHNEFISNLPNIKNYITNRK 218 >4Q5F-A nrPDB Length = 218 Score = 187 bits (476), Expect = 3e-48, Method: Composition-based stats. Identities = 57/216 (26%), Positives = 84/216 (38%), Gaps = 22/216 (10%) Query: 1 MP-MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN 59 MP L Y+DIRGL RL+ +E+ + D P K F Sbjct: 13 MPQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWP----------ALKPKTPFGQ 62 Query: 60 LPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN-- 117 LP L + QS AI Y+ R+ L G+T E+ +VD + +Q D +L C+ Sbjct: 63 LPLLEVDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAEL-RPCFRVL 121 Query: 118 PEFEK------LKPKYLEELPEKLKLYSEFLGKRP--WFAGNKITFVDFLVYDVLDLHRI 169 FE+ LK + + L L +FL K + G +T+ D ++ D L Sbjct: 122 AGFEEGDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWES 181 Query: 170 FEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP 205 P L LK +I L I ++ P Sbjct: 182 LIPDFLSGHLQLKKYIEHVRELPNIKKWIAERPKTP 217 >1GSQ-A nrPDB Length = 202 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 53/207 (25%), Positives = 86/207 (41%), Gaps = 18/207 (8%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+ + G A R +L + ++ M D P+ + + N +P Sbjct: 3 YTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNA----------MPV 52 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPE--F 120 L K++QS I ++AR+ L G+T EK RVD + D + I + PE Sbjct: 53 LDIDGTKMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAK 112 Query: 121 EKLKPKYLEELPEKLKLYSEFL-----GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCL 175 E ++ Y E+ ++L + E L G +F GN +T D Y L++ P+ L Sbjct: 113 EAVQQNY-EKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELL 171 Query: 176 DAFPNLKDFISRFEGLEKISAYMKSSR 202 P + R KI+AY+K Sbjct: 172 KDCPKIVALRKRVAECPKIAAYLKKRP 198 >1ZL9-A nrPDB Length = 207 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 48/214 (22%), Positives = 88/214 (41%), Gaps = 18/214 (8%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 + L Y++ RG R + Y YE+ + T + QW K F L Sbjct: 2 VSYKLTYFNGRGAGEVSRQIFAYAGQQYEDNRVT--------QEQWPALKETCAAPFGQL 53 Query: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQ-----LGMIC 115 P+L K+ QS+AI ++AR+ L G+T E+ +V+ L +Q D + ++ Sbjct: 54 PFLEVDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMG 113 Query: 116 YNP-EFEKLKPK-YLEELPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYDVLDLHRIFE 171 + P + E LK +L + FL + G+ +T++D + I + Sbjct: 114 FGPGDVETLKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQH-SADLIAK 172 Query: 172 PKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP 205 FP LK + + + +I ++++ P Sbjct: 173 GGDFSKFPELKAHAEKIQAIPQIKKWIETRPVTP 206 >1M0U-A nrPDB Length = 249 Score = 178 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 48/215 (22%), Positives = 95/215 (44%), Gaps = 28/215 (13%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 L Y++++ LA +R L Y + YE+ + T + P K + +P Sbjct: 49 SYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWP----------ALKPTMPMGQMP 98 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121 L ++ QS ++ ++A+ LCG T E +++DI+ + D +++ ++ Y PE E Sbjct: 99 VLEVDGKRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDE 158 Query: 122 -----------KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD-LHRI 169 ++ P YLE+L + +K L A K+T+ D + D ++ + Sbjct: 159 IKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHL------ALGKLTWADVYFAGITDYMNYM 212 Query: 170 FEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFL 204 + L+ +P L+ + LE I A+++ Sbjct: 213 VKRDLLEPYPALRGVVDAVNALEPIKAWIEKRPVT 247 >1GUL-A nrPDB Length = 222 Score = 175 bits (444), Expect = 1e-44, Method: Composition-based stats. Identities = 43/215 (20%), Positives = 86/215 (40%), Gaps = 22/215 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y + RG ++R +L ++E+ + Q + L F +P Sbjct: 5 PKLHYPNGRGRMESVRWVLAAAGVEFDEEFLE-------TKEQLYKLQDGNHLLFQQVPM 57 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 + K+ Q+ +IL YIA KHNL G+ +E+ +D+ T+D L M + ++ Sbjct: 58 VEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQ 117 Query: 123 LKP----------KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 K +Y + L+ + + + GN+++ D ++ + P Sbjct: 118 QKEVVNMAQKAIIRYFPVFEKILRGHGQ-----SFLVGNQLSLADVILLQTILALEEKIP 172 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRP 207 L AFP L+++ + + I +++ P Sbjct: 173 NILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPP 207 >2WDU-A nrPDB Length = 211 Score = 170 bits (431), Expect = 4e-43, Method: Composition-based stats. Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 22/215 (10%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+ RG A IRLLL +E+ ++TM P K L +P Sbjct: 6 FKLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPT----------IKPTLPGGRVPL 55 Query: 63 L----IDGAHKITQ-SNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN 117 L DG + Q S AI +AR+ + GET+EE ++ + + D + ++ I Sbjct: 56 LDVTGPDGKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRT 115 Query: 118 PEFE---KLKPKYLEELPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 P+ E K+K P LKL SE L AGN+IT D ++ L P Sbjct: 116 PQGEKEAKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVP 175 Query: 173 KCLD-AFPNLKDFISRFE-GLEKISAYMKSSRFLP 205 L+ FP L +F ++S Y+K P Sbjct: 176 GFLEQKFPKLHEFHKSLPTSCSRLSEYLKKRAKTP 210 >1U3I-A nrPDB Length = 211 Score = 168 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 53/220 (24%), Positives = 88/220 (40%), Gaps = 32/220 (14%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP- 61 + + Y+D RG A +IR+ L YE+++ + D P K K + LP Sbjct: 6 IKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWP----------KIKPTIPGGRLPA 55 Query: 62 --YLIDGAHK--ITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN 117 D H + +S AI Y+A+KH++ GET+EE V+ L Q D + Sbjct: 56 VKVTDDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMK 115 Query: 118 PEFEKLK----------PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLH 167 P+ EK K P + E LK + L G+K+T D ++ V+D Sbjct: 116 PQEEKEKITKEILNGKVPVLFNMICESLKGSTGKLA-----VGDKVTLADLVLIAVIDHV 170 Query: 168 RIFEPKCLD-AFPNLKDFISR-FEGLEKISAYMKSSRFLP 205 + L +P + +++ Y+ + P Sbjct: 171 TDLDKGFLTGKYPEIHKHRENLLASSPRLAKYLSNRPATP 210 >2CA8-A nrPDB Length = 211 Score = 167 bits (422), Expect = 5e-42, Method: Composition-based stats. Identities = 54/220 (24%), Positives = 91/220 (41%), Gaps = 32/220 (14%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 + + Y++ RG A +IR+ L +YE+++ + D P K K + LP Sbjct: 6 IKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWP----------KIKPTIPGGRLPA 55 Query: 63 L-IDGAHK----ITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN 117 + I H + +S AI Y+A+KH++ G TEEE V+ L Q D + Sbjct: 56 VKITDNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMK 115 Query: 118 PEFEKLK----------PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLH 167 PE EK K P L+ + E LK + L G+K+T D ++ V+D Sbjct: 116 PEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLA-----VGDKVTLADLVLIAVIDHV 170 Query: 168 RIFEPKCLD-AFPNLKDFISR-FEGLEKISAYMKSSRFLP 205 + + L +P + +++ Y+ P Sbjct: 171 TDLDKEFLTGKYPEIHKHRENLLASSPRLAKYLSDRAATP 210 >1YQ1-A nrPDB Length = 208 Score = 157 bits (397), Expect = 4e-39, Method: Composition-based stats. Identities = 51/215 (23%), Positives = 76/215 (35%), Gaps = 23/215 (10%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 L Y+ RGL IRLL +EE + WL+ K LP Sbjct: 3 SYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMNPD-------QTWLD--IKDSTPMKQLP 53 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN---- 117 L ++ QS AIL Y+ARK G+T EE+ VD + + D + Sbjct: 54 VLNIDGFELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSG 113 Query: 118 ---PEFEKLKPKYLEELPEKLKLYSEFLG-----KRPWFAGNKITFVDFLVYDVLDLHRI 169 E EK + ++ LP + ++ G + G+ ITF D +V D L + Sbjct: 114 KSAEEVEKFRSEFF--LPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKN 171 Query: 170 FEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFL 204 + F L + I Y+ Sbjct: 172 YGLFDESEFTKLAALREKVNSYPGIKEYIAKRPVT 206 >4Q5R-A nrPDB Length = 204 Score = 154 bits (390), Expect = 2e-38, Method: Composition-based stats. Identities = 47/213 (22%), Positives = 85/213 (39%), Gaps = 28/213 (13%) Query: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 L Y ++ L IR LL Y + +E+ ++ GD P+ K + F P Sbjct: 4 SYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPN----------LKPSMPFGKTP 53 Query: 62 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICY----- 116 L + QS AI Y+ ++ L G+ + E + +D++ + D + Y Sbjct: 54 VLEIDGKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADEN 113 Query: 117 ------NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDL-HRI 169 +P ++ P Y ++ E +K + A K+T+ DF +LD + + Sbjct: 114 SKQKKWDPLKKETIPYYTKKFDEVVK------ANGGYLAAGKLTWADFYFVAILDYLNHM 167 Query: 170 FEPKCLDAFPNLKDFISRFEGLEKISAYMKSSR 202 + + PNLK + GL I A++ Sbjct: 168 AKEDLVANQPNLKALREKVLGLPAIKAWVAKRP 200 >2HNL-A nrPDB Length = 225 Score = 119 bits (299), Expect = 8e-28, Method: Composition-based stats. Identities = 44/209 (21%), Positives = 84/209 (40%), Gaps = 20/209 (9%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y++ RG A IRLL + SYE+ + T + + K F ++P Sbjct: 28 YTLTYFNGRGRAEVIRLLFALANVSYEDNRITRDEW----------KYLKPRTPFGHVPM 77 Query: 63 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122 L + + +S+AI + + L G + E+ ++ + + +L + K Sbjct: 78 LNVSGNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTK 137 Query: 123 LKPKYLEELPEK-----LKLYSEFLGKR--PWFAGNKITFVDFLVYDVLDLHRIFEPKCL 175 K + L E L Y +FL + GNK++ D V+++L + L Sbjct: 138 -KAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLD--DEVKL 194 Query: 176 DAFPNLKDFISRFEGLEKISAYMKSSRFL 204 + +P L F+++ + I ++K Sbjct: 195 EEYPQLASFVNKIGQMPGIKEWIKKRPKT 223 >6F05-A nrPDB Length = 215 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 26/192 (13%) Query: 30 EKKYTMGDAP-DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKH---- 84 EK P D + + + F +P ++DG +KI +S A++ Y+A K+ Sbjct: 22 EKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYVAEKYRSQG 81 Query: 85 -NLCGETEEEKIRVDILENQT----------MDNHMQLGMICYNPEFEKLKPKYLEELPE 133 +L G+T E++ +V+ + + H+ + P EKL + E+L Sbjct: 82 PDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIKESEEKLAG 141 Query: 134 KLKLYSEFLGKRPWFAGNKITFV--------DFLVYDVLDLHRIFEPKCLDAFPNLKDFI 185 L +Y L K + AG+ ++ D+LV + + I + K + A+ + D Sbjct: 142 VLDVYEAHLSKSKYLAGDFVSLADLAHLPFTDYLVGPIGKAYMIKDRKHVSAWWD--DIS 199 Query: 186 SRFEGLEKISAY 197 SR E ++ Y Sbjct: 200 SRPAWKETVAKY 211 >5F07-A nrPDB Length = 213 Score = 113 bits (282), Expect = 8e-26, Method: Composition-based stats. Identities = 40/176 (22%), Positives = 59/176 (33%), Gaps = 17/176 (9%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKH-----NLCGETEEEK 94 D D + +F L F +P + DG K+ +S AI+ Y A K+ NL G T EEK Sbjct: 33 DLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEK 92 Query: 95 IRVDILENQTMDNHMQLGM----------ICYNPEFEKLKPKYLEELPEKLKLYSEFLGK 144 VD N L +L Y E+L + L +Y + L K Sbjct: 93 ALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQGDSELVRTYEEKLEKVLDVYEKRLSK 152 Query: 145 RPWFAGNKITFVDFLVYDV--LDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYM 198 + AG+ T D ++ + L + M Sbjct: 153 SKYLAGDSFTLADLSHLPATRYLVNEAGLGHLVKDRKKLNAWWEDISSRPAWKKLM 208 >4PNG-A nrPDB Length = 229 Score = 110 bits (274), Expect = 6e-25, Method: Composition-based stats. Identities = 41/190 (21%), Positives = 76/190 (40%), Gaps = 23/190 (12%) Query: 16 AIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNA 75 A++L L + YE + ++ +E+F +P L D H I S+A Sbjct: 23 AVKLTLAALEVPYEFVEVNTRAKENF------SEEFLKKNPQHTVPTLEDDGHYIWDSHA 76 Query: 76 ILCYIARKHNLCGETEEEKIRVDILENQTMD--NHMQLGMICYNPEFEKLKPKY------ 127 I+ Y+ K+ G+T+ + D+L+ +D H + G+I N KP + Sbjct: 77 IIAYLVSKY---GKTDSLYPK-DLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTM 132 Query: 128 -----LEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182 + + E +FL + AGN++T DF + + +F +P + Sbjct: 133 IPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIA 192 Query: 183 DFISRFEGLE 192 + R + L Sbjct: 193 AWFKRLQKLP 202 >4YH2-A nrPDB Length = 222 Score = 95.4 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 37/187 (19%), Positives = 71/187 (37%), Gaps = 17/187 (9%) Query: 16 AIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNA 75 A++L L + +YE D L+ ++ +P L D H I S+A Sbjct: 17 AVKLTLAALNLTYEYVNV------DIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHA 70 Query: 76 ILCYIARKHN----LCGETEEEKIRVDI---LENQTM---DNHMQLGMICYNPEFEKLKP 125 I+ Y+ K+ L + ++ VD E+ + + + + + K Sbjct: 71 IIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKE 130 Query: 126 KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFI 185 +Y + + E FL + + AGN++T DF + + F +P + +I Sbjct: 131 RY-DAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWI 189 Query: 186 SRFEGLE 192 + E L Sbjct: 190 KKLEQLP 196 >1AXD-A nrPDB Length = 209 Score = 91.5 bits (226), Expect = 3e-19, Method: Composition-based stats. Identities = 43/190 (22%), Positives = 67/190 (35%), Gaps = 20/190 (10%) Query: 21 LEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYI 80 LE S YE A + F +P L DG + +S AI Y Sbjct: 21 LEEAGSDYEIVPINFATAEHKSPEHLVRN------PFGQVPALQDGDLYLFESRAICKYA 74 Query: 81 ARKHN---LCGETEEEKIRVDILENQTMDNHMQLGMICYNPE----------FEKLKPKY 127 ARK+ L EE VD+ + + +K+ + Sbjct: 75 ARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDEN 134 Query: 128 LEELPEKLKLYSEFLGKRPWFAGNKITFVDF-LVYDVLDLHRIFEPKCLDAFPNLKDFIS 186 LE+L + L++Y L K + AG+ ++ D V L L LDA+P++K + S Sbjct: 135 LEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLFATPYASVLDAYPHVKAWWS 194 Query: 187 RFEGLEKISA 196 + Sbjct: 195 GLMERPSVQK 204 >5EY6-A nrPDB Length = 217 Score = 88.8 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 30/192 (15%), Positives = 65/192 (33%), Gaps = 19/192 (9%) Query: 30 EKKYTMGDAP-DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKH---- 84 EK P D + + + F +P D + + +S +I Y+ K+ Sbjct: 24 EKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESISLFESRSICRYVCEKYADRG 83 Query: 85 --NLCGETEEEKIRVDILEN----------QTMDNHMQLGMICYNPEFEKLKPKYLEELP 132 L G E+ +D + + P+ + + + E+L Sbjct: 84 DKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQDQGVIKQNEEKLG 143 Query: 133 EKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDL--HRIFEPKCLDAFPNLKDFISRFEG 190 + L +Y + LG+ + AG++ TF D D + + + N+ + + Sbjct: 144 KVLDIYEQRLGESRFLAGDEFTFADLSHLPNGDYLVNATDKGHLFTSRENVGRWWNEISD 203 Query: 191 LEKISAYMKSSR 202 E ++ + Sbjct: 204 RESWKKVIEMRK 215 >3VWX-A nrPDB Length = 222 Score = 85.4 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 32/189 (16%), Positives = 66/189 (34%), Gaps = 18/189 (9%) Query: 16 AIR---LLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQ 72 +R L L+ + +E K + + L+E++ +P L + H I Sbjct: 14 PVRACLLTLKALNLPFEYKVV------NLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWD 67 Query: 73 SNAILCYIARKHN----LCGETEEEKIRVD--ILENQ---TMDNHMQLGMICYNPEFEKL 123 S+AI+ Y+ K+ L + ++ VD + + + ++ Sbjct: 68 SHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQI 127 Query: 124 KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKD 183 ++ + E FL + AG+ +T DF + + F FP L Sbjct: 128 PQHQIDSIVESYGFLESFLKNNKYMAGDHLTIADFSIVTSVTSLVAFAEIDQSKFPKLSA 187 Query: 184 FISRFEGLE 192 ++ + L Sbjct: 188 WLKSLQSLP 196 >4RI7-A nrPDB Length = 215 Score = 85.4 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 65/179 (36%), Gaps = 17/179 (9%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKH------NLCGETEEE 93 D + + ++ F +P D + + +S AI YI K+ +L G Sbjct: 36 DLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILS 95 Query: 94 KIRVDILENQ--------TMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKR 145 K +D + D L + P E L K +++L + L +Y + LG+ Sbjct: 96 KANIDQWVETDGQTFGPPSGDLVHDL-LFSSVPVDEALIKKNVDKLAKVLDIYEQKLGQT 154 Query: 146 PWFAGNKITFVDFLVYDVLDL--HRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSR 202 + AG++ +F D D + + + N+ + + E ++ + Sbjct: 155 RFLAGDEFSFADLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLEMRK 213 >5F06-A nrPDB Length = 216 Score = 83.1 bits (204), Expect = 8e-17, Method: Composition-based stats. Identities = 31/195 (15%), Positives = 57/195 (29%), Gaps = 18/195 (9%) Query: 30 EKKYTMGDAP-DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCG 88 EK P D + F F +P L + + +S AI YIA K G Sbjct: 22 EKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDLTLFESRAITSYIAEKFKGTG 81 Query: 89 ------ETEEEKIRVDILENQTMD----------NHMQLGMICYNPEFEKLKPKYLEELP 132 E +E V + + + N + + +E+L Sbjct: 82 YDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMVAPLRGNSPDQTIIDDNVEKLG 141 Query: 133 EKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIF-EPKCLDAFPNLKDFISRFEGL 191 + L +Y L + AG+ + D ++ P++K + Sbjct: 142 KVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYLMKTPAASVVNERPHVKAWWEDISSR 201 Query: 192 EKISAYMKSSRFLPR 206 + F+ + Sbjct: 202 PAFKKVAEGMNFVKK 216 >1AW9-A nrPDB Length = 216 Score = 76.9 bits (188), Expect = 6e-15, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 61/183 (33%), Gaps = 18/183 (9%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEE----EKI 95 D F F +P L+DG + +S AI YIA K+ G Sbjct: 34 DLTTGAHKQPDFLALNPFGQIPALVDGDEVLFESRAINRYIASKYASEGTDLLPATASAA 93 Query: 96 RVDILENQTMDNHMQLGM----------ICYNPEFEKLKPKYLEELPEKLKLYSEFLGKR 145 ++++ + + + K+ E+L + L +Y L + Sbjct: 94 KLEVWLEVESHHFYPNASPLVFQLLVRPLLGGAPDAAVVDKHAEQLAKVLDVYEAHLARN 153 Query: 146 PWFAGNKITFVDFLVYDVLDLHRIF-EPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFL 204 + AG++ T D L + + A P++K + A+ K+ + Sbjct: 154 KYLAGDEFTLADANHASYLLYLSKTPKAGLVAARPHVKAWWEAIVARP---AFQKTVAAI 210 Query: 205 PRP 207 P P Sbjct: 211 PLP 213 >5A5K-A nrPDB Length = 212 Score = 75.0 bits (183), Expect = 2e-14, Method: Composition-based stats. Identities = 31/192 (16%), Positives = 57/192 (29%), Gaps = 25/192 (13%) Query: 21 LEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYI 80 L + +E + D + E F F +P DG K+ +S AI YI Sbjct: 22 LHEKNLDFELVHVELKDG------EHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYI 75 Query: 81 ARKHNLCGETEEE-------KIRVDILENQTMD-----------NHMQLGMICYNPEFEK 122 A ++ G + + + + Q D I E Sbjct: 76 AHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEA 135 Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHR-IFEPKCLDAFPNL 181 + + +L + L +Y L + + AG T D + K P + Sbjct: 136 VVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRV 195 Query: 182 KDFISRFEGLEK 193 ++++ Sbjct: 196 NEWVAEITKRPA 207 >5ZWP-A nrPDB Length = 208 Score = 74.2 bits (181), Expect = 4e-14, Method: Composition-based stats. Identities = 29/200 (14%), Positives = 70/200 (35%), Gaps = 17/200 (8%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y ++ + + +K + + L +F +P Sbjct: 1 MDFYYLPGSAPCRSVLMTAKALGIELNKKLLNLQ------AGEHLKPEFLKINPQHTIPT 54 Query: 63 LIDGAHKITQSNAILCYIARKHN----LCGETEEEKIRVDI-LENQTMDNHMQLGMICYN 117 L+DG + +S AI+ Y+ K+ L + +++ ++ L + Y Sbjct: 55 LVDGDFALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYP 114 Query: 118 PEFEK--LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCL 175 F K P+ +++ + FL + AG+ +T D + + + + Sbjct: 115 QIFAKAPADPELFKKIETAFDFLNTFLKGHEYAAGDSLTVADLALLASVSTFEV-ASFDI 173 Query: 176 DAFPNLKDFISRFEGLEKIS 195 +PN+ + + L+ ++ Sbjct: 174 SKYPNVAKW---YANLKTVA 190 >3LSZ-A nrPDB Length = 225 Score = 72.3 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 66/207 (31%), Gaps = 17/207 (8%) Query: 11 RGLAHAIRLLLEYTDSSYEEKKYTMGD--APDYDRSQWLNEKFKLGL---DFPNLPYLID 65 R A LL D +E + A + LN L +P L + Sbjct: 10 RSRASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPLGQIPCLEE 69 Query: 66 GAHKITQSNAILCYIARKHN--LCGETEEEKIRV---DILENQTMD---NHMQLGMICY- 116 +T+S AI +IAR L +E E + + ++ +QL Sbjct: 70 EGLILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQRSGG 129 Query: 117 --NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 +PE + E L L + G + T D + + L + P Sbjct: 130 GTSPEGQAAIAIAAERLRRPLARLERHFAAEDYLVGGRFTVADLNLAETLRYGQAH-PAL 188 Query: 175 LDAFPNLKDFISRFEGLEKISAYMKSS 201 L+ FP + ++ R + M+ Sbjct: 189 LEPFPAVAAWLDRCQSRPAFRLMMERR 215 >1PN9-A nrPDB Length = 209 Score = 72.3 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 72/202 (35%), Gaps = 28/202 (13%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y A+++ K D + + + +F +P Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKL------TDLMKGEHMKPEFLKLNPQHCIPT 54 Query: 63 LIDGAHKITQSNAILCYIARKHN----LCGETEEEKIRV------DI--LENQTMDNHM- 109 L+D + +S AI Y+A K+ L + +++ V D+ L + D H Sbjct: 55 LVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYP 114 Query: 110 -QLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHR 168 NPE EK ++ + + + FL + + AGN +T D + + + Sbjct: 115 QIFAKQPANPENEK-------KMKDAVGFLNTFLEGQEYAAGNDLTIADLSLAATIATYE 167 Query: 169 IFEPKCLDAFPNLKDFISRFEG 190 + +PN+ + +R + Sbjct: 168 V-AGFDFAPYPNVAAWFARCKA 188 >2C3Q-A nrPDB Length = 247 Score = 71.1 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 40/197 (20%), Positives = 68/197 (34%), Gaps = 25/197 (12%) Query: 13 LAHAIRLLLEYT---DSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHK 69 L+ R + + D +E + D + Q L++ F +P L DG Sbjct: 17 LSQPCRAVYIFAKKNDIPFELRIV------DLIKGQHLSDAFAQVNPLKKVPALKDGDFT 70 Query: 70 ITQSNAILCYIARKHNL----CGETEEEKIRVDILEN-QTMDNHM----------QLGMI 114 +T+S AIL Y+ RK+ + + + + RVD Q + Sbjct: 71 LTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVF 130 Query: 115 CYNPEFEKLKPKYLEELPEKLKLYS-EFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 P + L EL L+L +FL + + G I+ D + L + Sbjct: 131 LGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQ 190 Query: 174 CLDAFPNLKDFISRFEG 190 + P L + R E Sbjct: 191 VFEGRPKLATWRQRVEA 207 >4MPF-A nrPDB Length = 266 Score = 70.7 bits (172), Expect = 5e-13, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 76/212 (35%), Gaps = 37/212 (17%) Query: 7 YWDIRGL-------AHAIRLLLEYT---DSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD 56 Y+ GL + R + + E + D + Q +++F Sbjct: 19 YFQSMGLELFLDLVSQPSRAVYIFAKKNGIPLELRTV------DLVKGQHKSKEFLQINS 72 Query: 57 FPNLPYLIDGAHKITQSNAILCYIARKH----NLCGETEEEKIRVDILENQTMD-NHMQL 111 LP L DG +T+S+AIL Y++ K+ + + + RV D Sbjct: 73 LGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTF 132 Query: 112 GMICY-------------NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDF 158 G+ + + E+ + + L + L+ +FLG RP+ AG ++T D Sbjct: 133 GIPLWVQVLGPLIGVQVPKEKVERNRTAMDQAL-QWLE--DKFLGDRPFLAGQQVTLADL 189 Query: 159 LVYDVLDLHRIFEPKCLDAFPNLKDFISRFEG 190 + + L + + P L + R E Sbjct: 190 MALEELMQPVALGYELFEGRPRLAAWRGRVEA 221 >2IL3-A nrPDB Length = 221 Score = 69.6 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 33/188 (17%), Positives = 65/188 (34%), Gaps = 17/188 (9%) Query: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 A+ L + E+K + F +P L D IT+S Sbjct: 15 CRAVELTAKALGLELEQKTINLLTGDHLKPE------FVKLNPQHTIPVLDDNGTIITES 68 Query: 74 NAILCYIARKHN----LCGETEEEKIRVDI---LENQTM--DNHMQLGMICYNPEFEKLK 124 +AI+ Y+ K+ L + ++ RV+ E+ + I + + + + Sbjct: 69 HAIMIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFGKSDIPE 128 Query: 125 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDF 184 + +E + + +L + L + AG +T DF + P P + + Sbjct: 129 DR-VEYVQKSYELLEDTLVD-DFVAGPTMTIADFSCISTISSIMGVVPLEQSKHPRIYAW 186 Query: 185 ISRFEGLE 192 I R + L Sbjct: 187 IDRLKQLP 194 >1JLV-A nrPDB Length = 209 Score = 68.0 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 33/199 (16%), Positives = 68/199 (34%), Gaps = 28/199 (14%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y A+++ K + + + +F +P Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKL------TNLMAGEHMKPEFLKINPQHCIPT 54 Query: 63 LIDGAHKITQSNAILCYIARKHN----LCGETEEEKIRV------DI--LENQTMDNHM- 109 L+D + +S AI Y+A K+ L + +++ V D+ L + D + Sbjct: 55 LVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYP 114 Query: 110 -QLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHR 168 N E EK ++ + + + FL + AG+ +T D V + + Sbjct: 115 QIFAKQPANAENEK-------KMKDAVDFLNTFLDGHKYVAGDSLTIADLTVLATVSTYD 167 Query: 169 IFEPKCLDAFPNLKDFISR 187 + L +P++ + R Sbjct: 168 V-AGFELAKYPHVAAWYER 185 >5F0G-A nrPDB Length = 215 Score = 68.0 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 13/174 (7%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y G + ++ + +K + + L +F +P Sbjct: 1 MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEG------EQLKPEFVKLNPQHTIPT 54 Query: 63 LIDGAHKITQSNAILCYIARKHN----LCGETEEEKIRVDILENQTMDNHMQLGMICYNP 118 L+D I +S AI Y+ K+ L +++ ++ M + Y P Sbjct: 55 LVDNGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYP 114 Query: 119 EFEKLKP---KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI 169 F KP + L+ + FL + + AG+++T D + + + Sbjct: 115 LFRTGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTFEV 168 >2GDR-A nrPDB Length = 202 Score = 66.9 bits (162), Expect = 7e-12, Method: Composition-based stats. Identities = 35/211 (16%), Positives = 75/211 (35%), Gaps = 17/211 (8%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L Y + L ++E + + +L +P Sbjct: 1 MKLYYSPGACSLSP-HIALREAGLNFELVQVDLASKKTASGQDYLEVN-----PAGYVPC 54 Query: 63 LI-DGAHKITQSNAILCYIARKHNLCGETEE------EKIRVDILENQTMDNHMQLGMIC 115 L D +T+ AI+ Y+A + + G+ E+ + N + Sbjct: 55 LQLDDGRTLTEGPAIVQYVADQ--VPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPL 112 Query: 116 YNP-EFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 +NP ++ K + L +L + L P+ G++++ D ++ VL + Sbjct: 113 FNPASSDEWKNAVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYLFVVL-GWSAYVNID 171 Query: 175 LDAFPNLKDFISRFEGLEKISAYMKSSRFLP 205 L +P+L+ F R G E + + +++ + Sbjct: 172 LSPWPSLQAFQGRVGGREAVQSALRAEGLIK 202 >5F05-A nrPDB Length = 212 Score = 66.1 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 25/153 (16%), Positives = 51/153 (33%), Gaps = 15/153 (9%) Query: 56 DFPNLPYLIDGAHKITQSNAILCYIARKH----NLCGETEEEKIRVDILENQTMDNH--- 108 F +P +DG K+ +S AI Y+A ++ G + + + Sbjct: 50 PFGQVPAAVDGDLKLFESRAISQYVAHQYASKGTQLGAAGNGYATILVWQEVESHQFDPS 109 Query: 109 -------MQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDF-LV 160 + P L + L + L +Y L + + A + T D + Sbjct: 110 ASKLVWEQVFKPVFGLPTDAALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHL 169 Query: 161 YDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEK 193 ++ L K D+ P++ +++ G Sbjct: 170 PNIQALLGTPSKKLFDSRPHVSAWVASITGRPA 202 >2CZ2-A nrPDB Length = 223 Score = 66.1 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 31/188 (16%), Positives = 63/188 (33%), Gaps = 22/188 (11%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 +R+ L YE + D Q E+F+ +P L I QS AI Sbjct: 27 VRIALALKGIDYEIVPINL----IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAI 82 Query: 77 LCYIARKH---NLCGETEEEKIRVDILEN---------QTMDNHMQLGMICYNPEFEKLK 124 + Y+ L + +++ V ++ + Q + Q+G +K+ Sbjct: 83 MEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVI 142 Query: 125 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDF 184 L + L+ + + G++++ D + + F+ L +P + Sbjct: 143 TSGFNALEKILQSTAG-----KYCVGDEVSMADVCLVPQVANAERFK-VDLSPYPTISHI 196 Query: 185 ISRFEGLE 192 LE Sbjct: 197 NKELLALE 204 >3UAR-A nrPDB Length = 227 Score = 66.1 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 40/205 (19%), Positives = 71/205 (34%), Gaps = 12/205 (5%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M M L Y+ ++L +E + +G + +L K + L Sbjct: 1 MVMKLYYFPGACSLAP-HIVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQL 59 Query: 61 PYLIDGAHKITQSNAILCYIAR---KHNLCGET-EEEKIRVDILENQTMDNHMQLGMICY 116 D +T+ IL Y+A + L + E+ R+ + + Sbjct: 60 ----DDGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFW 115 Query: 117 NPEF-EKLKPKYLEELPEKLKLYSEFL-GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174 NPE E K L L +L + L PW G++ + D + VL + Sbjct: 116 NPESPEASKQIALGLLSRRLDYVEDRLEAGGPWLMGDRYSVADAYLSTVLGWCEYLKID- 174 Query: 175 LDAFPNLKDFISRFEGLEKISAYMK 199 L +P + ++ R + + A MK Sbjct: 175 LSKWPRILAYLERNQARPAVQAAMK 199 >3M3M-A nrPDB Length = 210 Score = 66.1 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 37/203 (18%), Positives = 70/203 (34%), Gaps = 17/203 (8%) Query: 1 MPMILGYWDIR-GLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN 59 M + Y D R G + I+L+L YE A D E F Sbjct: 1 MSLYKVYGDYRSGNCYKIKLMLNLLGLPYE------WQAVDILGGDTQTEAFLAKNPNGK 54 Query: 60 LPYLI-DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMI---- 114 +P L + + +SNAIL ++A + +V + +H + Sbjct: 55 IPVLELEDGTCLWESNAILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFI 114 Query: 115 -CYNPEFEKLKPKYLE---ELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIF 170 Y E+ + +YL+ + L + + L + P+ G + D +Y Sbjct: 115 QLYEGLPEERREEYLKLHKRGYKALDVMEKQLSRTPYLVGEHYSIADIALY-AYTHVADE 173 Query: 171 EPKCLDAFPNLKDFISRFEGLEK 193 L +P ++ ++ R + + Sbjct: 174 GGFDLSRYPGIQAWMQRVQSHPR 196 >3MAK-A nrPDB Length = 209 Score = 65.7 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 24/173 (13%), Positives = 59/173 (34%), Gaps = 13/173 (7%) Query: 6 GYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID 65 Y ++ + + +K + + L +F +P L+D Sbjct: 5 YYLPGSSPCRSVIMTAKAVGVELNKKLLNLQ------AGEHLKPEFLKINPQHTIPTLVD 58 Query: 66 GAHKITQSNAILCYIARKHN----LCGETEEEKIRVDI-LENQTMDNHMQLGMICYNPEF 120 + +S AI Y+ K+ L + +++ ++ L + Y F Sbjct: 59 NGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVF 118 Query: 121 EKL--KPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFE 171 K P+ +++ + + FL + + AG+ +T D + + + + Sbjct: 119 AKAPADPEAFKKIEAAFEFLNTFLEGQDYAAGDSLTVADIALVATVSTFEVAK 171 >1V2A-A nrPDB Length = 210 Score = 64.6 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 35/196 (17%), Positives = 74/196 (37%), Gaps = 19/196 (9%) Query: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 + LL + + KK + D + D LN + +P L+D H + +S Sbjct: 12 CQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQH-------TIPTLVDNGHVVWES 64 Query: 74 NAILCYIARKH----NLCGETEEEKIRVDILENQTMDNHMQLGMIC----YNPEFEKLKP 125 AI+ Y+ + L + + + V+ D I + E+ Sbjct: 65 YAIVLYLVETYAKDDTLYPKDPKVRSVVNQ--RLFFDIGTLYKRIIDVIHLVMKKEQPSD 122 Query: 126 KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFI 185 + +E+L L L +F+ +R + A + +T D + + + L+ FP+++ ++ Sbjct: 123 EQMEKLKGALDLLEQFVTERAYAAADHLTVADICLLGTVTALNWLK-HDLEPFPHIRAWL 181 Query: 186 SRFEG-LEKISAYMKS 200 R + + K Sbjct: 182 ERVRAEMPDYEEFSKQ 197 >1FW1-A nrPDB Length = 216 Score = 63.8 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 30/189 (15%), Positives = 62/189 (32%), Gaps = 22/189 (11%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 +R+ L Y+ + D Q ++ F+ +P L I QS AI Sbjct: 20 VRIALALKGIDYKTVPINL----IKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAI 75 Query: 77 LCYIARKH---NLCGETEEEKIRVDILEN---------QTMDNHMQLGMICYNPEFEKLK 124 + Y+ L + +++ V ++ + Q + Q+G + Sbjct: 76 IEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAI 135 Query: 125 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDF 184 L + L+ + + G+++T D + + F+ L +P + Sbjct: 136 TCGFNALEQILQSTAGI-----YCVGDEVTMADLCLVPQVANAERFK-VDLTPYPTISSI 189 Query: 185 ISRFEGLEK 193 R LE Sbjct: 190 NKRLLVLEA 198 >1F2E-A nrPDB Length = 201 Score = 61.9 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 37/185 (20%), Positives = 65/185 (35%), Gaps = 12/185 (6%) Query: 21 LEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL-IDGAHKITQSNAILCY 79 L T + +E K + R E F +P L +D +T++ AIL Y Sbjct: 18 LRETGADFEAVKVDLA-----VRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLY 72 Query: 80 IARKHNLCGETEEE-----KIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEK 134 IA ++ G E + L + H + ++ K E + Sbjct: 73 IADQNPASGLAPAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNH 132 Query: 135 LKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKI 194 L + L R +AGN + D +Y +L + + A+P L + + + Sbjct: 133 LAALDKELAGRDHYAGNAFSVADIYLYVML-GWPAYVGIDMAAYPALGAYAGKIAQRPAV 191 Query: 195 SAYMK 199 A +K Sbjct: 192 GAALK 196 >3M8N-A nrPDB Length = 225 Score = 61.9 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 68/200 (34%), Gaps = 17/200 (8%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L G ++ +RL L D+ Y + D R + F +P Sbjct: 4 YKLYSMQRSGNSYKVRLALALLDAPYRAVEV------DILRGESRTPDFLAKNPSGQVPL 57 Query: 63 LIDG-AHKITQSNAILCYIARKHNLCGETEEEKIRVD--ILENQTM---DNHMQLGMICY 116 L + +SNAIL Y+A +L +T ++ + Q + +C Sbjct: 58 LETAPGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCL 117 Query: 117 NPEFEKLK----PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP 172 L+ +LE L++ L +FA ++T D +Y + + Sbjct: 118 VKGGRDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQCDF 177 Query: 173 KCLDAFPNLKDFISRFEGLE 192 L FP + ++ R E Sbjct: 178 D-LSTFPAVNAWLRRVEQTP 196 >3LFL-A nrPDB Length = 240 Score = 60.0 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 79/198 (39%), Gaps = 22/198 (11%) Query: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 A RL+L+ +E + + P +W +K F +P L + ++ Sbjct: 35 AERTRLVLKAKGIRHEVININLKNKP-----EWFFKKN----PFGLVPVLENSQGQLIYE 85 Query: 74 NAILC-YIARKH---NLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLE 129 +AI C Y+ + L + EK ++ ++ + + + K Y Sbjct: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILE----LFSKVPSLVGSFIRSQNKEDYAG 141 Query: 130 ELPEKLKLYSEF----LGKRPWFAGNKITFVDFLVYDVLDLHRIFE-PKCLDAFPNLKDF 184 E K +++ K +F GN I+ +D+L++ + + +C+D P LK + Sbjct: 142 LKEEFRKEFTKLEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLW 201 Query: 185 ISRFEGLEKISAYMKSSR 202 ++ + +SA + S + Sbjct: 202 MAAMKEDPTVSALLTSEK 219 >3IBH-A nrPDB Length = 233 Score = 59.6 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 29/180 (16%), Positives = 59/180 (32%), Gaps = 16/180 (8%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLI-DGAHKITQSNAILCYIARKHN---LCGETEEEKI 95 + + + +F +P L D I + AI YI L G+T EK Sbjct: 52 NLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKG 111 Query: 96 RVDILENQTM-------DNHMQLGMICYNPEFEKLKPKYL-----EELPEKLKLYSEFLG 143 + ++ + + PE E + K ++ + + L Sbjct: 112 VIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLR 171 Query: 144 KRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRF 203 +RP+ AG+ + D V L I + + + L+ + R + + ++ Sbjct: 172 ERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLEIRSK 231 >3TOT-A nrPDB Length = 226 Score = 58.0 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 62/199 (31%), Gaps = 25/199 (12%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI-DGAHKITQSNA 75 +R++L Y+ + N +P L+ D + S Sbjct: 17 VRVVLAEKKIDYQ--FVLEDVWNADTQIHQFN-------PLGKVPCLVMDDGGALFDSRV 67 Query: 76 ILCY------IARKHNLCGETEEE----KIRVDILENQTMDNHMQLGMICYNPEFEKLKP 125 I Y +AR G E + D L + + ++ E Sbjct: 68 IAEYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRSESWIT 127 Query: 126 KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC--LDAFPNLKD 183 + ++ E LK S L R W GN +T D V L +P+ + NL Sbjct: 128 RQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQHANLAA 187 Query: 184 FISRFEGLEKISAYMKSSR 202 F +R E ++++ Sbjct: 188 FYTRIEKRPS---FLETQP 203 >4IKH-A nrPDB Length = 244 Score = 58.0 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 39/202 (19%), Positives = 77/202 (38%), Gaps = 25/202 (12%) Query: 20 LLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID----GA--HKITQS 73 +LE YE + + ++ + +F +P ++D G + +S Sbjct: 39 MLEEIGLPYEAHRVS------FETQDQMTPEFLSVSPNNKIPAILDPHGPGDQPLALFES 92 Query: 74 NAILCYIARKHN--LCGETEEEKIRVDILENQTMDNHMQLGMICYN-----PEFEKLKP- 125 AIL Y+A K L E+ + L Q G + + E+E +P Sbjct: 93 GAILIYLADKSGQLLAQESAARYETIQWLMFQMGGIGPMFGQVGFFNKFAGREYEDKRPL 152 Query: 126 -KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVY----DVLDLHRIFEPKCLDAFPN 180 +Y+ E L + + LG R W G + T D + +++ + E +D FP Sbjct: 153 ERYVNEAKRLLGVLDKHLGGREWIMGERYTIADIATFPWIRNLIGFYEAGELVGIDNFPE 212 Query: 181 LKDFISRFEGLEKISAYMKSSR 202 +K +++F + ++ + Sbjct: 213 VKRVLAKFVARPAVIRGLEIPK 234 >3GH6-A nrPDB Length = 210 Score = 57.3 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 23/174 (13%), Positives = 59/174 (33%), Gaps = 12/174 (6%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L Y ++ + + +++K + + ++ +P Sbjct: 1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTI-----INTRAREQFTPEYLKINPQHTIPT 55 Query: 63 LIDGAHKITQSNAILCYIARKHN----LCGETEEEKIRVDILENQTMDNHMQLGMICYNP 118 L D + +S AI+ Y+ K+ L + +++ ++ M + Y P Sbjct: 56 LHDHGFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYP 115 Query: 119 EFEKLKP---KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI 169 + KP + +++ + + FL + + AG + D + + Sbjct: 116 QIFLKKPANEENYKKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVSTFDV 169 >2PVQ-A nrPDB Length = 201 Score = 55.3 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 30/183 (16%), Positives = 54/183 (29%), Gaps = 12/183 (6%) Query: 20 LLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDG-AHKITQSNAILC 78 +L YE + + D + +P L ITQ+ AIL Sbjct: 17 ILSEAGLPYELEAVDLKAKKTADGGDYFAVN-----PRGAVPALEVKPGTVITQNAAILQ 71 Query: 79 YIARKHNLCGETEE----EKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEK 134 YI ++ E+ R+ D H + E+ + + + + Sbjct: 72 YIGDHSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVIANINRR 131 Query: 135 LKLYSEFLG-KRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEK 193 L L K ++ G+ T D V+ + + L A+P R Sbjct: 132 LGQLEAMLSDKNAYWLGDDFTQPD-AYASVIIGWGVGQKLDLSAYPKALKLRERVLARPN 190 Query: 194 ISA 196 + Sbjct: 191 VQK 193 >4MDC-A nrPDB Length = 252 Score = 54.6 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 34/235 (14%), Positives = 72/235 (30%), Gaps = 40/235 (17%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MP L + + + +RL+L Y+ + + LN L Sbjct: 23 MP-TLYHHPMSPASRFVRLILSEYG--YQTELSEEQPWENRRDFLTLN-------PAGTL 72 Query: 61 PYLIDGAHK-----------ITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD--- 106 P +D + + + +++ I+ R L E ++ + L + Sbjct: 73 PVYVDDSMRALCGATIISEYLDETSGIMK---RDRRLLAEDPFQRAEIRRLTEWFLQKME 129 Query: 107 -------NHMQLGMICYNPE------FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKI 153 ++ + P+ K+ + + +K S G RPW AG++I Sbjct: 130 ADVTRPLVRERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRI 189 Query: 154 TFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 ++ D + + P K++ R + + PV Sbjct: 190 SYGDLAAAAAISVLDYLGEIDWSDAPTAKEWYQRLKSRPSFRPLLAERVRGVTPV 244 >2PMT-A nrPDB Length = 203 Score = 53.8 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 66/198 (33%), Gaps = 13/198 (6%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L Y ++L T + ++ + +L K +P Sbjct: 1 MKLYYTPGSCSLSP-HIVLRETGLDFSIERIDLRTKKTESGKDFLAINPK-----GQVPV 54 Query: 63 LI-DGAHKITQSNAILCYIAR---KHNLCG--ETEEEKIRVDILENQTMDNHMQLGMICY 116 L D +T+ AI+ Y+A NL + E +++ L + H + Sbjct: 55 LQLDNGDILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFS 114 Query: 117 NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD 176 + E P +L K ++ L K+ G+ T D ++ L L Sbjct: 115 SDTPESYLPVVKNKLKSKFVYINDVLSKQKCVCGDHFTVADAYLF-TLSQWAPHVALDLT 173 Query: 177 AFPNLKDFISRFEGLEKI 194 +L+D+++R + Sbjct: 174 DLSHLQDYLARIAQRPNV 191 >3UBL-A nrPDB Length = 242 Score = 53.8 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 35/167 (20%), Positives = 51/167 (30%), Gaps = 24/167 (14%) Query: 25 DSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKH 84 YE+ + D+ + +P L I +S AIL ++ Sbjct: 26 GLEYEQIRIAPSQEEDFLKIS----------PMGKIPVLEMDGKFIFESGAILEFLDTIF 75 Query: 85 ----NLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKL----K 136 L E E RV + Y P K+ P+ +EE+ L K Sbjct: 76 PQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAA-KVSPEIVEEVHSTLVKGIK 134 Query: 137 LYSEFLGKRPWFAGNKITFVD---FLVYDVLDLHRIFEPKCLDAFPN 180 + P+ AGN T D F VLD P + P Sbjct: 135 ALQRVVRFSPYIAGNVFTLADCSGFAHLSVLD--EELRPFYPNNHPL 179 >4CHS-A nrPDB Length = 219 Score = 53.4 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 39/196 (19%), Positives = 68/196 (34%), Gaps = 17/196 (8%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 +R+ L YE K+ D L + +P LI I++S Sbjct: 19 VRIALAEKGIEYEYKE------EDLRNKSPLLLQMNPV--HKKIPVLIHNGKPISESLIA 70 Query: 77 LCYIARKHN----LCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELP 132 + YI N L ++ + + LG + + E+ K +E Sbjct: 71 VQYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEE-KEAAKKEFI 129 Query: 133 EKLKLYSEFLGKRPWFAGNKITFVDFLV---YDVLDLHRIFEPKCLDA-FPNLKDFISRF 188 E LKL E LG + +F G+ I FVD + Y ++ F ++ P + R Sbjct: 130 EALKLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENECPRFVAWAKRC 189 Query: 189 EGLEKISAYMKSSRFL 204 E ++ + + Sbjct: 190 LQKESVAKSLPDQHKV 205 >5F8B-A nrPDB Length = 244 Score = 52.6 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 21/117 (17%), Positives = 44/117 (37%), Gaps = 16/117 (13%) Query: 57 FPNLPYLI-DGAHKITQSNAILCYIARK---HNLCGETEEEKIRV---------DILENQ 103 +P + K+ + AI YI + L G+ ++E + +I+ Sbjct: 47 LGKVPAFQGADSFKLFECMAIALYITSQNEQTTLLGKDKKEYAEIIKWMSFFNTEIVILM 106 Query: 104 TMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLV 160 T QLG+I Y+ + + + + E+L R + G++++ D Sbjct: 107 TQQLLPQLGVIPYDRD---QVEFFANMTQRSVDVVEEYLQDRTFLVGDQLSLADLFC 160 >5J5N-A nrPDB Length = 231 Score = 51.5 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 67/208 (32%), Gaps = 17/208 (8%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 +RL L YE +N K +P L+ + +S I Sbjct: 31 VRLALAEKGVKYE--YSEEDLWNKSALLLQMNPVNK------QIPVLVHNGKPVCESLII 82 Query: 77 LCYIARKHN----LCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELP 132 + YI L ++ + + LG + + E+ + ++ Sbjct: 83 VQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEE-QEAAKKDFI 141 Query: 133 EKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP----KCLDAFPNLKDFISRF 188 + LKL LG +P+F G I +VD + +E P + + R Sbjct: 142 DSLKLMEGELGDKPYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKMIAYCKRC 201 Query: 189 EGLEKISAYMKSSRFLPRPVFSKMAVWG 216 E +S ++ + + V M +G Sbjct: 202 LQKETVSKALEDPQKVYDFVLMLMKKFG 229 >2VO4-A nrPDB Length = 219 Score = 51.1 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 38/196 (19%), Positives = 65/196 (33%), Gaps = 17/196 (8%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 +R+ L YE K+ D L + +P LI I +S Sbjct: 19 VRIALAEKGIKYEYKE------EDLRNKSPLLLQMNP--VHKKIPVLIHNGKPICESLIA 70 Query: 77 LCYIARKHN----LCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELP 132 + YI N L ++ + + LG + + E+ K +E Sbjct: 71 VQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEE-KEAAKKEFI 129 Query: 133 EKLKLYSEFLGKRPWFAGNKITFVDFLV---YDVLDLHRIF-EPKCLDAFPNLKDFISRF 188 E LKL E LG + +F G+ + FVD + Y + F P + R Sbjct: 130 EALKLLEEQLGDKTYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIESECPKFIAWAKRC 189 Query: 189 EGLEKISAYMKSSRFL 204 E ++ + + + Sbjct: 190 LQKESVAKSLPDQQKV 205 >4FQU-A nrPDB Length = 313 Score = 49.9 bits (118), Expect = 7e-07, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 44/138 (31%), Gaps = 15/138 (10%) Query: 72 QSNAILCYIARKHNLCGETEEEKI------RVDILENQT-MDNHMQLGMICYNPEFEKLK 124 +S+ I+ + + G + +D + + + + + E + Sbjct: 137 ESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYE 196 Query: 125 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD-------A 177 + + L E L R W G+++T D ++ L Sbjct: 197 EAFYPLF-DTLDWLEEHLTGREWLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIAD 255 Query: 178 FPNLKDFISRFEGLEKIS 195 +PNL + + E+++ Sbjct: 256 YPNLSRLVGKLASHERVA 273 >1E6B-A nrPDB Length = 221 Score = 49.9 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 64/205 (31%), Gaps = 20/205 (9%) Query: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 AH +R+ L YE + +D FK +P L+DG I S Sbjct: 20 AHRVRIALALKGLDYEYIPVNLLKGDQFDSD------FKKINPMGTVPALVDGDVVINDS 73 Query: 74 NAILCYIARKH---NLCGETEEEKIR----VDILENQTMDNHMQLGMICYNPE---FEKL 123 AI+ Y+ K+ L ++ + I+ + H L +I Y E E+ Sbjct: 74 FAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQ-PHQNLAVIRYIEEKINVEEK 132 Query: 124 KPKYLEELPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNL 181 + + + L G++I D + + ++ +P L Sbjct: 133 TAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQINMEPYPTL 192 Query: 182 KDFISRFEGLEKISAYM-KSSRFLP 205 + L + + P Sbjct: 193 AKCYESYNELPAFQNALPEKQPDAP 217 >4J2F-A nrPDB Length = 223 Score = 48.8 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 51/157 (32%), Gaps = 12/157 (7%) Query: 59 NLPYLIDGAHKITQSNAILCYIARKHN---LCGETEEEKIRVDILENQTMDNHMQLGMIC 115 +P L+ G I +S IL Y+ L E+ D + I Sbjct: 53 KIPVLVHGGKPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIF 112 Query: 116 YN--PEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDF------LVYDVLDLH 167 E EK LE L + ++ ++ + +F G+KI VD V++ Sbjct: 113 RTKGEELEKAVKNCLEVL-KTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEV 171 Query: 168 RIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFL 204 + FP L + F+ I + + Sbjct: 172 AGVKVLESQKFPRLHAWTENFKEAPIIKENLPDRDQM 208 >4PXO-A nrPDB Length = 238 Score = 48.8 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 44/212 (20%), Positives = 66/212 (31%), Gaps = 24/212 (11%) Query: 2 PMILGYWDIRGLAH-AIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M+ Y + R A +R+ L +YEE D D F + Sbjct: 22 SMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFL------DLDAGDQHKPDFLAINPQGAV 75 Query: 61 PYLIDGA-HKITQSNAILCYIARK---HNLCGETEEEKIRVDILENQTM-DNH------- 108 P L DG +TQS AIL Y+ L E + R L D H Sbjct: 76 PALFDGDGPPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRV 135 Query: 109 MQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFL----GKRPWFAGNKITFVDFLVYDVL 164 M Y E++ LK L G + G+ ++ D + + Sbjct: 136 RTFLMENYGLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLW 195 Query: 165 DLHRIFEPKCLDAFPNLKDFISRFEGLEKISA 196 IF A+P +K L+ ++ Sbjct: 196 VGTGIF-GIDTAAYPTVKRISEEVLALDAVAR 226 >3PR8-A nrPDB Length = 229 Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 42/236 (17%), Positives = 74/236 (31%), Gaps = 33/236 (13%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M + L + + + ++L L ++EE + G AP + Sbjct: 1 MSLKLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQALEVS----------PRGKV 50 Query: 61 PYLIDGAHKITQSNAILCYIARKHN---LCGETEEEKIRVDILENQTMDNHMQLGMICYN 117 P L +++++ IL YI + L + +V L + CY Sbjct: 51 PVLETEHGFLSETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYA 110 Query: 118 PEF----------EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLH 167 F EK + L LK F P+ AG ++T D + +DL Sbjct: 111 ESFFGMSVEPLIKEKARADLLAGF-ATLKRNGRF---APYVAGEQLTLADLMFCFSVDLA 166 Query: 168 -----RIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 ++ L FP K + + + P F +M G + Sbjct: 167 NAVGKKVLNIDFLADFPQAKALLQLMGENPHMPRILADKE-ASMPAFMEMIRSGKR 221 >3GX0-A nrPDB Length = 215 Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 38/207 (18%), Positives = 66/207 (31%), Gaps = 33/207 (15%) Query: 7 YWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDG 66 Y+ H I L LE + Y K D + +F +P ++D Sbjct: 5 YFAPTPNGHKITLFLEEAELDYRLIKV------DLGKGGQFRPEFLRISPNNKIPAIVDH 58 Query: 67 A-------HKITQSNAILCYIARKHNLC--GETEEEKIRVDILENQTMDN---------- 107 + + +S AIL Y+A K L ET E + L Q Sbjct: 59 SPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHF 118 Query: 108 -HMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDL 166 H I Y E +++ + + ++ L PW G + D + ++ Sbjct: 119 NHAAPQTIPYAIERYQVETQ------RLYHVLNKRLENSPWLGGENYSIADIACWPWVNA 172 Query: 167 HRIFEPKCLDAFPNLKDFISRFEGLEK 193 + L +P +K++ R Sbjct: 173 W-TRQRIDLAMYPAVKNWHERIRSRPA 198 >1N2A-A nrPDB Length = 201 Score = 48.0 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 51/147 (34%), Gaps = 7/147 (4%) Query: 56 DFPNLPYLIDGAHKIT-QSNAILCYIARKHN----LCGETEEEKIRVDILENQTMDNHMQ 110 +P L+ + + AI+ Y+A L + + N + Sbjct: 48 PKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIATELHK 107 Query: 111 LGMICYNPEF-EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI 169 + P+ E+ KP +L +KL+ +E L W G + T D ++ VL Sbjct: 108 GFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVL-RWAY 166 Query: 170 FEPKCLDAFPNLKDFISRFEGLEKISA 196 L+ ++ F+ R ++ Sbjct: 167 AVKLNLEGLEHIAAFMQRMAERPEVQD 193 >4G0L-A nrPDB Length = 328 Score = 48.0 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 52/157 (33%), Gaps = 22/157 (14%) Query: 59 NLPYLIDGA-HKIT--QSNAILCYIARKHNLCGETEEEKI------RVDILENQTMDNHM 109 +P L D H I +S I+ + G + ++D L D Sbjct: 132 TVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDT-- 189 Query: 110 QLGMICYNPEFEKLKPKYLEELPEK---LKLYSEFLGKRPWFAGNKITFVDFLVYDVL-- 164 + Y F + Y E + + L + LG+ + GN++T D ++ L Sbjct: 190 -VNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVR 248 Query: 165 -----DLHRIFEPKCLDAFPNLKDFISRFEGLEKISA 196 H + + + NL F+ + I+ Sbjct: 249 FDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAE 285 >4BVY-B nrPDB Length = 186 Score = 47.2 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 56/160 (35%), Gaps = 25/160 (15%) Query: 59 NLPYLI-DGAHKITQSNAILCYIARKHN---LCGETEEEKIRVDILEN---QTMDNHMQL 111 +P L + +T I ++ ++ N L G T EEK V +D H Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSK 100 Query: 112 GMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI-F 170 ++ LK + +L + + G T D L+Y L + Sbjct: 101 -----------------NDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDL 143 Query: 171 EPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFS 210 + + + N+ + S + I ++ S F+ +++ Sbjct: 144 TVQEKEKYLNVSRWFSHIQHYPGIRQHLSSVVFIKNRLYT 183 >5LOL-A nrPDB Length = 215 Score = 46.9 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 36/155 (23%), Positives = 53/155 (34%), Gaps = 23/155 (14%) Query: 19 LLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILC 78 L LE Y+ + D P QW F +P + + S+ I+ Sbjct: 30 LTLEEKKLPYKTHLINVSDKP-----QW----FLDISPEGKVPVVKLDGKWVADSDVIVG 80 Query: 79 YIARKH---NLCGETEEEKIRV-DILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEK 134 + K+ +L +T E V + + L N EK LE L Sbjct: 81 LLEEKYPEPSL--KTPPEFASVGSKIFGAFVTF---LKSKDANDGSEKALVDELEALENH 135 Query: 135 LKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI 169 LK +S P+ AG KIT VD + L + Sbjct: 136 LKTHSG-----PFVAGEKITAVDLSLAPKLYHLEV 165 >3PPU-A nrPDB Length = 352 Score = 46.5 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 57/171 (33%), Gaps = 20/171 (11%) Query: 43 RSQWLNEKFKLGLDFPNLPYLID---GAHKITQSNAILCYIARKHN-LCGET-------- 90 + +L K F +P L D G +S+ I+ N L E Sbjct: 142 KDLYLKVKPDYDGRF-TVPVLWDKHTGTIVNNESSEIIRMFNTAFNHLLPEDKAKLDLYP 200 Query: 91 EEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAG 150 E + ++D + + D +K + L E L + L + + G Sbjct: 201 ESLRAKIDEVNDWVYDTVNNGVYKSGFASTQKAYEAAVIPLFESLDRLEKMLEGQDYLIG 260 Query: 151 NKITFVDFLVYDVLDLHRIFEPKCLDAFP-NLKDFISRFEGLEKISAYMKS 200 ++T D ++ + F+P + F NL+ G + +M+ Sbjct: 261 GQLTEADIRLFVTIVR---FDPVYVTHFKCNLRTIRD---GYPNLHRWMRK 305 >3C8E-A nrPDB Length = 288 Score = 46.1 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 64/204 (31%), Gaps = 41/204 (20%) Query: 19 LLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAH----KITQSN 74 L L T + Y+ +GD + + F +P L D H ++ +S Sbjct: 66 LALGVTGAEYDAWLIRIGDGDQF------SSGFVEVNPNSKIPALRDHTHNPPIRVFESG 119 Query: 75 AILCYIARKHN------LCGETE------EEKIRVDILENQTMDNHMQLGMICYNPEF-E 121 +IL Y+A K L TE + L + Y P E Sbjct: 120 SILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYH------YAPVKIE 173 Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYD---------VLDLHRIFEP 172 ++ E L + + L + + AG++ T D ++ V D + Sbjct: 174 YAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDA 233 Query: 173 KCLDAFPNLKDFISRFEGLEKISA 196 ++ +++ + + Sbjct: 234 G---SYKHVQRWAKEVGERPAVKR 254 >5NR1-A nrPDB Length = 228 Score = 46.1 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 33/208 (15%), Positives = 63/208 (30%), Gaps = 28/208 (13%) Query: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 L ++ + + +RL L + E + + P +F P L Sbjct: 6 TLHHFPLDPASRQVRLALGEKRLPFVEMQVRYWEMP---------PEFTSLNPSGMPPVL 56 Query: 64 IDGAHK----ITQSNAILCYIARKHN---LCGETEEEKIRV------------DILENQT 104 ++ H+ I ++ AIL +I L G E+ + + Sbjct: 57 VETKHQRNLVICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFL 116 Query: 105 MDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVL 164 + M+ ++ + E L L L R W AG +++ DF L Sbjct: 117 LHEKMEKRLLRMGAPDLAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHL 176 Query: 165 DLHRIFEPKCLDAFPNLKDFISRFEGLE 192 + F F K + + + Sbjct: 177 SVIDYFGDVPWKDFQAAKTWYMKLKSRP 204 >3QAG-A nrPDB Length = 239 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 36/193 (18%), Positives = 70/193 (36%), Gaps = 20/193 (10%) Query: 15 HAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKI-TQS 73 H RL+L+ D +E + + P +W K F ++P L ++ +S Sbjct: 36 HRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKH----PFGHIPVLETSQSQLIYES 86 Query: 74 NAILCYIARKH---NLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEE 130 Y+ + L E+ R +L + Sbjct: 87 VIACEYLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRSGRESTNLKAA 146 Query: 131 LPEKLKLYSEFL--GKRPWFAGNKITFVDFLV---YDVLDLHRIFEPKCLDAFPNLKDFI 185 L ++ E L +F G I+ +D+L+ ++ LD++ I + C+ P L+ +I Sbjct: 147 LRQEFSNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDVYGILD--CVSHTPALRLWI 204 Query: 186 SRFEGLEKISAYM 198 S + +SA + Sbjct: 205 SAMKWDPTVSALL 217 >5ECL-B nrPDB Length = 223 Score = 44.5 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 33/212 (15%), Positives = 69/212 (32%), Gaps = 18/212 (8%) Query: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 +P++L YW A R+ L +E + D S + + Sbjct: 10 LPILLDYWPSMFGMRA-RVALREKGVEFE--------YREEDFSNKSPLLLQSNPIHKKI 60 Query: 61 PYLIDGAHKITQSNAILCYI----ARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICY 116 P L+ + +S ++ Y+ K+ + + + + Sbjct: 61 PVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVW 120 Query: 117 NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEP---- 172 + E+ + +E E +K+ LG +P+F G+ +VD + + +E Sbjct: 121 GKKGEEQEAG-KKEFIEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNF 179 Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFL 204 P L + R E +S + S + Sbjct: 180 SIESESPKLIAWAKRCMEKESVSKSLPDSEKI 211 >4QQ7-A nrPDB Length = 207 Score = 43.8 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 28/201 (13%), Positives = 63/201 (31%), Gaps = 21/201 (10%) Query: 15 HAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSN 74 RL+L +E + + + P+ + +P L++ + +SN Sbjct: 18 QRCRLVLFEKGMDFEIRDVDLFNKPEDISVMN---------PYGQVPILVERDLILYESN 68 Query: 75 AILCYIARKH---NLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLE-- 129 I YI + L ++ R + ++ +L + E EK K Sbjct: 69 IINEYIDERFPHPQLMPADPVQRARARLF---LLNFEKELFVHVSTLENEKGKAAEKNHE 125 Query: 130 ----ELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFI 185 + ++L + K + G + + +D + +L + + L + Sbjct: 126 KARLAIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRLDHYGIELSKNAAPLMKYA 185 Query: 186 SRFEGLEKISAYMKSSRFLPR 206 R + S + R Sbjct: 186 ERIFSRPAYIEALTPSEKVMR 206 >2JL4-A nrPDB Length = 213 Score = 43.4 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 36/196 (18%), Positives = 67/196 (34%), Gaps = 22/196 (11%) Query: 3 MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L + G +H +R+ L YE A + + L + FK +P Sbjct: 2 MKLYNFWRSGTSHRLRIALNLKGVPYE------YLAVHLGKEEHLKDAFKALNPQQLVPA 55 Query: 63 LIDGAHKITQSNAILCYIARKH---NLCGETEEEKIRVDILENQT-MDNH-------MQL 111 L GA + QS AI+ ++ ++ L + + RV L D H ++ Sbjct: 56 LDTGAQVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEY 115 Query: 112 GMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRP----WFAGNKITFVDFLVYDVLDLH 167 + + + + Y L P + G+ T D + ++ Sbjct: 116 LRKTFGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESA 175 Query: 168 RIFEPKCLDAFPNLKD 183 R F+ L +P ++ Sbjct: 176 RRFQ-VDLTPYPLIRA 190 >5ELG-A nrPDB Length = 221 Score = 43.4 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 36/205 (17%), Positives = 68/205 (33%), Gaps = 25/205 (12%) Query: 19 LLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILC 78 L LE +Y+ + D P QW F +P L +T S+ I+ Sbjct: 28 LTLEEKSLTYKIHLINLSDKP-----QW----FLDISPQGKVPVLKIDDKWVTDSDVIVG 78 Query: 79 YIARKH-NLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKL 137 + K+ + +T E V T ++ E L LE L LK Sbjct: 79 ILEEKYPDPPLKTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVE--LEALENHLKS 136 Query: 138 YSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC-----LDAFPNLKDFISRFEGLE 192 + P+ AG +++ VD + L ++ ++FP++ +++ L Sbjct: 137 HDG-----PFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLFSL- 190 Query: 193 KISAYMKSSRFLPRPVFSKMAVWGN 217 ++ K+ + Sbjct: 191 --DSFEKTKTEEKYVISGWAPKVNP 213 >6GCB-A nrPDB Length = 325 Score = 43.0 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 38/221 (17%), Positives = 70/221 (31%), Gaps = 41/221 (18%) Query: 9 DIRGLAHAIRL-----LLEYTDSSYEEKKYTMGDAPD------YDRSQWLNEKFKLGLDF 57 I+GL + + L + + G D Y R +L K F Sbjct: 67 KIKGLEEIVGVTIVSPLFSAHGWPFGDVSPFPGAEADPFYNAQYVRDLYLRADPKYEGRF 126 Query: 58 PNLPYLIDGAHKIT---QSNAILCYIARKHN-----------LCGETEEEKIRVDILENQ 103 +P L D + +S+ I+ N L E + + +D + Sbjct: 127 -TVPVLWDKKTETVVNNESSEIIRIFNTAFNEFLPADKAAIHLYPEALKSE--IDEINEW 183 Query: 104 TMDNHMQLGMICYNPEFEKLKPKYLEE---LPEKLKLYSEFLGKRPWFAGNKITFVDFLV 160 D + Y F + Y L E L + L + + G+++T D + Sbjct: 184 VYDT---VNNGVYKAGFATTQQAYEAAVIPLFESLDRLEKILTGKDYLVGDQLTEADVRL 240 Query: 161 YDVLDLHRIFEPKCLDAFP-NLKDFISRFEGLEKISAYMKS 200 + + F+P + F NL+ G I +++ Sbjct: 241 FVTIIR---FDPAYVGHFKCNLRTIRD---GYPAIHLWLRK 275 >4USS-A nrPDB Length = 325 Score = 43.0 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 56/157 (35%), Gaps = 23/157 (14%) Query: 59 NLPYLIDGAHKIT---QSNAILCYIARKHNLCGET-------EEEKIRVDILENQTMDNH 108 +P L D K +S+ I+ + N E + ++D D Sbjct: 128 TVPVLWDKKLKTIVNNESSEIIRMFNTEFNDIAENAALDLYPSHLQAQIDETNGWVYD-- 185 Query: 109 MQLGMICYNPEFEKLKPKYLEE---LPEKLKLYSEFLGKRPWFAGNKITFVDFLVY---- 161 + Y F + + Y E L E L E LG++ + GN ++ D ++ Sbjct: 186 -GINNGVYKCGFARKQGPYEEAAIQLYEALDKCEEILGRQRYICGNTLSEADIKLFVTLI 244 Query: 162 ---DVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKIS 195 +V +H K L +PN+ ++ + +S Sbjct: 245 RFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMS 281 >4IGJ-A nrPDB Length = 242 Score = 42.6 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 37/191 (19%), Positives = 62/191 (32%), Gaps = 25/191 (13%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI---DG-AHKITQ 72 +RL L +YE + A D + + +P L DG H + Q Sbjct: 39 VRLGLALKGLAYEYR------AVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQ 92 Query: 73 SNAILCYIARKH---NLCGETEEEKIRVDILEN----QTMDNHMQLGMICYN---PEFEK 122 S AIL ++ +H L + RV L T L + P +++ Sbjct: 93 SMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLREKVPGWDR 152 Query: 123 LKPKYLEELPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 ++ + L + G + G+ T D + L R F L+ +P Sbjct: 153 EWARFF--IARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRF-GLDLEPYPT 209 Query: 181 LKDFISRFEGL 191 L+ L Sbjct: 210 LRRVDEACAAL 220 >6GZF-A nrPDB Length = 341 Score = 41.5 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 51/139 (36%), Gaps = 20/139 (14%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLID---GAHKITQSNAILCYIARKHN--------LCG 88 DY R ++ + +P L D +S I+ + + L Sbjct: 115 DYLRELYVRAAPDVTCRV-TVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYP 173 Query: 89 ETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEK---LKLYSEFLGKR 145 E +EK VD + + + + + Y F + Y E + E L + + L + Sbjct: 174 EGYQEK--VDQIID---NIYEPINNGVYRAGFATEQEPYDEAVAELFGALAHWDDVLADQ 228 Query: 146 PWFAGNKITFVDFLVYDVL 164 + AG+++T D ++ L Sbjct: 229 RYLAGDRLTEADIAMFTTL 247 >6GC9-A nrPDB Length = 327 Score = 41.1 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 39/111 (35%), Gaps = 13/111 (11%) Query: 94 KIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEE---LPEKLKLYSEFLGKRPWFAG 150 + +D + D + Y F + Y L E L + L + + G Sbjct: 175 RGEIDGINEWVYDT---VNNGVYKSGFATSQKAYEAAVVPLFESLDRLEKILTGKDYLVG 231 Query: 151 NKITFVDFLVYDVLDLHRIFEPKCLDAFP-NLKDFISRFEGLEKISAYMKS 200 +++T D ++ + F+P + F N++ G I +M+ Sbjct: 232 DQLTEADIRLFVTIVR---FDPVYVGHFKCNIRTIRD---GYPAIDLWMRK 276 >6EP7-A nrPDB Length = 220 Score = 40.3 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 51/158 (32%), Gaps = 9/158 (5%) Query: 59 NLPYLIDGAHKITQSNAILCYI----ARKHNLCGETEEEKIRVDILENQTMDNHMQLGMI 114 +P LI I +S + YI + + ++ + + Sbjct: 53 KIPVLIHEGKPICESIIQVQYIDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKA 112 Query: 115 CYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD----LHRIF 170 ++ EK + +E E LK LG + +F GN+ VD + Sbjct: 113 LWSESGEKQEAAKIE-FIEVLKTLDSELGDKYYFGGNEFGLVDIAFIGFYSWFRTYEEVA 171 Query: 171 EPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208 + FP L + R E ++ + S + + V Sbjct: 172 NLSIVLEFPKLMAWAQRCLKRESVAKALPDSDKVLKSV 209 >4PTS-A nrPDB Length = 348 Score = 39.9 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 36/125 (28%), Gaps = 8/125 (6%) Query: 91 EEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAG 150 E + +D + C + + L KL SE L ++ + G Sbjct: 165 EHLRAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQRYLVG 224 Query: 151 NKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFS 210 + IT D ++ L K S+ + + AY + P F Sbjct: 225 DTITEADVRLFTTLARFDAVYHGHF------KCNRSKLSEMPVLWAY--ARDLFQTPGFG 276 Query: 211 KMAVW 215 + Sbjct: 277 DTTDF 281 >5N9U-A nrPDB Length = 218 Score = 38.0 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 33/173 (19%), Positives = 54/173 (31%), Gaps = 31/173 (17%) Query: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 + L LE Y+ +GD P QW F +P + + S Sbjct: 23 CQRVLLSLEEKKIPYKSHLINLGDKP-----QW----FLEISPEGKVPVVKIDDKWVADS 73 Query: 74 NAILCYIARKHN---LCGETEEEKIRVDILENQTMDNHMQLGMICYNPE----FEKLKPK 126 + I+ + K+ L T E V + + E+ + Sbjct: 74 DVIVGILEEKNPEPPLA--TPPEFASVGS------KIFPSFVKFLKSKDPNDGTEQALLE 125 Query: 127 YLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFP 179 L+ L LK++ P+ AG KIT VD + L + +P Sbjct: 126 ELKALDGHLKVHG------PFIAGEKITAVDLSLAPKLYHLEVAL-GHFKNWP 171 >3RBT-A nrPDB Length = 246 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 37/212 (17%), Positives = 82/212 (38%), Gaps = 26/212 (12%) Query: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L + D+ H + L+LE YE + P++ R++ K +P L Sbjct: 29 LYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLK---------IPVLE 79 Query: 65 D----GAHKITQSNAILCYIARK---HNLCGETEEEKIRVDILENQTMDNHMQLGMICYN 117 G + +S I Y+ K H L K + +L + + ++ + C++ Sbjct: 80 IPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNEL-IKGSLECFD 138 Query: 118 PEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIF----EPK 173 F + ++ L K + +F GN+ +D++V+ ++ + + K Sbjct: 139 TNFAFGSEQIIQTLEIFEKELTNR--GTNYFGGNRPGMLDYMVWPWVERLYLLRCVNDRK 196 Query: 174 CLDA---FPNLKDFISRFEGLEKISAYMKSSR 202 ++ FPN D+ + + + + + S + Sbjct: 197 FVEKKSLFPNFADWGDQMQLDDIVKKHAHSPQ 228 >3M1G-A nrPDB Length = 362 Score = 37.2 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 29/107 (27%), Gaps = 9/107 (8%) Query: 109 MQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHR 168 + + E Y + L L + L R + G+ IT D +Y L Sbjct: 198 NGVYRTGFAGSQEAHNEAY-KRLWVALDWLEDRLSTRRYLMGDHITEADIRLYPTLVRFD 256 Query: 169 IFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVW 215 K ++ + + Y+ P F + Sbjct: 257 AVYHGHF------KCGRNKITEMPNLWGYL--RDLFQTPGFGDTTDF 295 >1G6W-A nrPDB Length = 261 Score = 36.8 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 25/213 (11%), Positives = 56/213 (26%), Gaps = 58/213 (27%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLID---GAHKITQSNAILCYIARKHN-------LCGE 89 D++ + +F +P LID I +S AIL ++ K+ L + Sbjct: 52 DFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSD 111 Query: 90 TEEEKIRVDIL-----------ENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLY 138 ++ +++ Q + + +Y +E+ + Sbjct: 112 DLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAV-----ERYTDEVRRVYGVV 166 Query: 139 SEFLGKRP--------------------------------WFAGNKITFVDFLVYDVLDL 166 L +R W G+K+T D ++ Sbjct: 167 EMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNV 226 Query: 167 HRIFEPKCLDAFPNLKDFISRFEGLEKISAYMK 199 FP + + + ++ Sbjct: 227 VDRIGINIKIEFPEVYKWTKHMMRRPAVIKALR 259 >3IR4-A nrPDB Length = 218 Score = 36.1 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 23/182 (12%), Positives = 61/182 (33%), Gaps = 20/182 (10%) Query: 33 YTMGDAPDYDRSQWLNEKFKLGLDFPN--LPYLI-DGAHKITQSNAILCYIARKHNLCGE 89 + + + P +++ +P L D + + +S I+ Y+ NL G+ Sbjct: 22 FGLKNIPVELNVLQNDDEATPTRMIGQKMVPILQKDDSRYLPESMDIVHYVD---NLDGK 78 Query: 90 ---TEEEKIRVDILENQTMDNHMQLGMICYNPE-FEK-----LKPKYLEELPEKLKLYSE 140 T + ++ + QL + + F++ + ++ + + Sbjct: 79 PLLTGKRNPAIEEWLRKVNGYVNQLLLPRFAKSAFDEFSTPAARQYFIRKKEASSGSFDN 138 Query: 141 FLGKRPWFA---GNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK--DFISRFEGLEKIS 195 L G+ + +D L+ ++ + FP L+ ++ K++ Sbjct: 139 HLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGELSEDDIHLFPLLRNLTLVAGIHWPTKVA 198 Query: 196 AY 197 Y Sbjct: 199 DY 200 >6JWK-A nrPDB Length = 222 Score = 34.1 bits (77), Expect = 0.043, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 25/65 (38%), Gaps = 7/65 (10%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID-GAHKITQSNA 75 +R+ L Y+ + + + L + LP L+D + +QS A Sbjct: 15 VRIALALKGLDYQVVPV------NLRQGEQLRPADRQRNPMGALPTLVDADGRRFSQSLA 68 Query: 76 ILCYI 80 I+ Y+ Sbjct: 69 IIDYL 73 >4PQI-A nrPDB Length = 241 Score = 32.6 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 21/145 (14%), Positives = 44/145 (30%), Gaps = 13/145 (8%) Query: 59 NLPYLIDGAHKITQSNAILCYIARKH---NLCGETEEEKIRVDILENQTMDNHMQLGMIC 115 +P L +S ++ Y+ +L + +K + L D Sbjct: 83 KVPSLEHNGKITGESLDLIKYLESNFEGPSLLPKDPAKKEFAEELF-SYTDKFNGTVYTA 141 Query: 116 YNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD-----LHRIF 170 + + K + L L + + P+F G + + VD ++ L +F Sbjct: 142 FKGDLAKEAGPAFDHLENALHKFDDG----PFFLGKEFSLVDIAYIPFVERLNIFLLEVF 197 Query: 171 EPKCLDAFPNLKDFISRFEGLEKIS 195 + L +I +E Sbjct: 198 KYDITAGRQKLAAWIEEVNKIEAYK 222 >3BBY-A nrPDB Length = 215 Score = 31.8 bits (71), Expect = 0.21, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 20/45 (44%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKH 84 D D + L ++ +P L ++++S+AI Y+ + Sbjct: 40 DLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRF 84 >1G7O-A nrPDB Length = 215 Score = 31.8 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 23/195 (11%), Positives = 64/195 (32%), Gaps = 28/195 (14%) Query: 18 RLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI-DGAHKITQSNAI 76 R++ + E DA R +P L D + + +S I Sbjct: 16 RMIFGLKNIPVELHVLLNDDAETPTRMVGQK----------QVPILQKDDSRYMPESMDI 65 Query: 77 LCYIARKHNLCGE---TEEEKIRVDILENQTMDNHMQLGMICYNPE-FEK-----LKPKY 127 + Y+ + L G+ T + ++ + +L + + F++ + + Sbjct: 66 VHYVDK---LDGKPLLTGKRSPAIEEWLRKVNGYANKLLLPRFAKSAFDEFSTPAARKYF 122 Query: 128 LEELPEKLKLYSEFLGKRPWF---AGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK-- 182 +++ +++ L + + +D L+ ++ + FP L+ Sbjct: 123 VDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVKPNAVNGELSEDDIQLFPLLRNL 182 Query: 183 DFISRFEGLEKISAY 197 ++ +++ Y Sbjct: 183 TLVAGINWPSRVADY 197 >3NIV-A nrPDB Length = 222 Score = 31.1 bits (69), Expect = 0.35, Method: Composition-based stats. Identities = 32/209 (15%), Positives = 68/209 (32%), Gaps = 22/209 (10%) Query: 1 MPMILG-YWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPN 59 M +IL Y+ + +R+ L +YE + + + + ++ Sbjct: 1 MSLILYDYFRSTA-CYRVRIALNLKKIAYE----KIEVHLVNNGGEQHSLQYHQINPQEL 55 Query: 60 LPYLIDGAHKITQSNAILCYIARKH---NLCGETE-EEKIRVDILENQTMDNH------- 108 +P L ++QS AI+ Y+ H L + + + D H Sbjct: 56 VPSLDINGQILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRV 115 Query: 109 MQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLG----KRPWFAGNKITFVDFLVYDVL 164 + +N E++ Y L + E LG +P G+++ D + + Sbjct: 116 LNRLKEQFNANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQV 175 Query: 165 DLHRIFEPKCLDAFPNLKDFISRFEGLEK 193 F + ++P + + L Sbjct: 176 YNAHRFHFD-MASYPIINEINEYCLTLPA 203 >1GWC-A nrPDB Length = 230 Score = 31.1 bits (69), Expect = 0.40, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 59/200 (29%), Gaps = 33/200 (16%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 ++L L SYE+ + D + K +P LI + +S I Sbjct: 21 VKLALALKGLSYEDV--------EEDLYKKSELLLKSNPVHKKIPVLIHNGAPVCESMII 72 Query: 77 LCYIARKH-----NLCGETEEEKIRVDILENQTMDNH----MQLGMICYNPEFEKLKPKY 127 L YI +L E+ D Q E + K + Sbjct: 73 LQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTEEEKSEGKKQA 132 Query: 128 LEE---LPEKLKLYSEFLGKR--------PWFAGNKITFVDFLVYDVLDLHRIFEPKCLD 176 L L+ S+ G G +++ V + L +IF+ Sbjct: 133 FAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSW--MKVTEALSGDKIFDAA--- 187 Query: 177 AFPNLKDFISRFEGLEKISA 196 P L ++ RF L+ A Sbjct: 188 KTPLLAAWVERFIELDAAKA 207 >5HSX-A nrPDB Length = 323 Score = 29.9 bits (66), Expect = 0.91, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 +R + ++ + + T AP + + ++P DG TQS AI Sbjct: 254 VRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDG----TQSVAI 309 >5JMV-A nrPDB Length = 348 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 16/88 (18%) Query: 76 ILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN--PEFEKL--KPKYLEEL 131 ++ Y+++K+ + GET +DI +D + + + P E+L K K L +L Sbjct: 140 VIAYVSKKYRVFGET------LDIAVGNCLDQFARYVNLPHPGGPYIEELARKGKKLVDL 193 Query: 132 PEKLKL----YSEFL--GKRPWFAGNKI 153 P +K +S L R + AG ++ Sbjct: 194 PYTVKGMDIAFSGLLTAAMRAYDAGERL 221 >2IWR-A nrPDB Length = 178 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 7/42 (16%), Positives = 20/42 (47%) Query: 66 GAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDN 107 G + +S+ I ++ + + +TE E+ + ++L + Sbjct: 14 GDARSGKSSLIHRFLTGSYQVLEKTESEQYKKEMLVDGQTHL 55 >6AIY-A nrPDB Length = 378 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 19/40 (47%) Query: 116 YNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITF 155 Y P E+++ + L L+ ++ G W AG +T+ Sbjct: 86 YQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTW 125 >3FQJ-A nrPDB Length = 417 Score = 29.1 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 19/40 (47%) Query: 116 YNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITF 155 Y P E+++ + L L+ ++ G W AG +T+ Sbjct: 112 YQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTW 151 >5KEU-A nrPDB Length = 323 Score = 29.1 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 21/60 (35%), Gaps = 4/60 (6%) Query: 17 IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAI 76 +R E ++ + + T AP + + ++P DG QS AI Sbjct: 254 VRFKWEAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGR----QSVAI 309 >2JZR-A nrPDB Length = 144 Score = 29.1 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 5/40 (12%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCY 79 D D +W GL++P LP + D I QS I Y Sbjct: 74 DGDFQKWYA-----GLNYPKLPVVTDNGGTIAQSLNISVY 108 >4D9F-A nrPDB Length = 342 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 173 KCLDAFPNLKDFISR---FEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 L FP L +FI E L ++S Y+ ++ R + +A+ GNK Sbjct: 18 HHLTRFPRL-EFIGAPTPLEYLPRLSDYLGREIYIKRDDVTPIAMGGNK 65 >4K0G-A nrPDB Length = 251 Score = 28.8 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 22/135 (16%), Positives = 43/135 (31%), Gaps = 22/135 (16%) Query: 55 LDFPNLPYLIDGAHKITQSNAILCYIARKHNLCG-ETEEEKIRVDILENQTMDNHMQLGM 113 LP+L+ G T +N I ++ + LC + +D + Sbjct: 69 CPGGQLPFLLYGTEVHTDTNKIEEFL--EAVLCPPRYPKLAALNPESNTAGLDIFAKFSA 126 Query: 114 ICYNPEFEKLKPKYLEELPEKLKLYSEFL------------------GKRPWFAGNKITF 155 N L + L + LK+ +L +R + GN++T Sbjct: 127 YIKNSN-PALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTL 185 Query: 156 VDFLVYDVLDLHRIF 170 D + L + ++ Sbjct: 186 ADCNLLPKLHIVQVV 200 >4CZI-A nrPDB Length = 348 Score = 28.4 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 3/38 (7%) Query: 63 LIDGAHKITQSNAILCYIARKHNLC-GETEEEKIRVDI 99 + G K+ + AI+ Y+ R HNL GET E+I+ +I Sbjct: 177 VRVGGDKMDE--AIISYMRRHHNLLIGETTAERIKKEI 212 >5LKB-A nrPDB Length = 378 Score = 28.4 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 38/85 (44%), Gaps = 12/85 (14%) Query: 96 RVDILENQTMDNHMQLGMI--CYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKI 153 + ++ E++ + L + + ++ KLK KY E ++ K+ EF + G+++ Sbjct: 231 KAEVYESEVNNVFEHLDKVEKILSDKYSKLKAKYGE--EDRQKILGEF-----FTVGDQL 283 Query: 154 TFVDFLVYDVLDLHRIFEPKCLDAF 178 T D +Y F+P + F Sbjct: 284 TEADIRLYTT---VIRFDPVYVQHF 305 >4J15-A nrPDB Length = 521 Score = 28.4 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 38/123 (30%), Gaps = 31/123 (25%) Query: 85 NLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGK 144 L G +EK D +D + Y + P++ Y F+ Sbjct: 394 KLLGHLVKEKYDTDFY---ILDKYPLAVRPFYTMPDPRN--------PKQSNSYDMFMRG 442 Query: 145 RPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFL 204 +G + RI +P+ L + LEKI AY+ S RF Sbjct: 443 EEILSGAQ---------------RIHDPQLLTE----RALHHGI-DLEKIKAYIDSFRFG 482 Query: 205 PRP 207 P Sbjct: 483 APP 485 >3ENH-A nrPDB Length = 540 Score = 28.4 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 16/88 (18%) Query: 76 ILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYN--PEFEKL--KPKYLEEL 131 ++ Y+++K+ + GET +DI +D + + + P E+L K K L +L Sbjct: 140 VIAYVSKKYRVFGET------LDIAVGNCLDQFARYVNLPHPGGPYIEELARKGKKLVDL 193 Query: 132 PEKLKL----YSEFL--GKRPWFAGNKI 153 P +K +S L R + AG ++ Sbjct: 194 PYTVKGMDIAFSGLLTAAMRAYDAGERL 221 >5KOD-A nrPDB Length = 612 Score = 28.0 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 53/148 (35%), Gaps = 13/148 (8%) Query: 74 NAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPE 133 NA + Y+ R+H+L G T+ E + + D ++ I +K + + E Sbjct: 50 NADVEYL-RRHDLNGRTDRETFKNIMPVITYEDIEPEINRI---ANGDKSPILSSKPISE 105 Query: 134 KLKLYSEFLGKRPWF--AGNKITFVDFLVYDVLDLHRIFEPKCLDA----FPNLKDFISR 187 L G+R ++ L ++ + F P + F +K Sbjct: 106 FLTSSGTSGGERKLMPTIEEELDRRSLLYSLLMPVMSQFVPGLENGKGMYFLFIKSESKT 165 Query: 188 FEGLEK---ISAYMKSSRFLPRPVFSKM 212 GL +++Y KSS F RP Sbjct: 166 PGGLPARPVLTSYYKSSHFKERPYDPYT 193 >2YV7-A nrPDB Length = 260 Score = 28.0 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 46/122 (37%), Gaps = 18/122 (14%) Query: 61 PYLIDGAHKITQSNAILCYIARK----HNLCGETEEEKIRVDILENQTMDNHMQLGMICY 116 P LID I ++ I +I + +NL + +E ++ + +++L ++ Sbjct: 85 PILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIE-------NLYVKLKLMLV 137 Query: 117 NPEFEKLKPKYLEELPEKLKLYSEFLGKRP--WFAGNKITFVDFLVYDVLDLHRIFEPKC 174 + K L L+ ++ L R + G+ + D + L R+ Sbjct: 138 KKDEAKN-----NALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYF 192 Query: 175 LD 176 +D Sbjct: 193 VD 194 >2PAR-A nrPDB Length = 201 Score = 28.0 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 26/70 (37%), Gaps = 1/70 (1%) Query: 80 IARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYS 139 IA+++ + ++K VD++ + D L + EK K + L LK Sbjct: 91 IAQEYKAIEKIAQQK-LVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLE 149 Query: 140 EFLGKRPWFA 149 E F Sbjct: 150 ELAAGNNEFL 159 >3LG6-A nrPDB Length = 235 Score = 28.0 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 20/65 (30%), Gaps = 2/65 (3%) Query: 142 LGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKI-SAYMKS 200 L + G++IT D + + L FP K E + A+ + Sbjct: 167 LSAGRFCVGDEITLADVCLVPAVWAAER-VGMDLARFPITKRVFEEMLKEEAVQKAHWQK 225 Query: 201 SRFLP 205 P Sbjct: 226 QEDTP 230 >5TDL-A nrPDB Length = 531 Score = 27.6 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 156 VDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFL 204 V L + VLDL + + L P L + R +E + + + + L Sbjct: 148 VSVLTFKVLDLKNYIDKELL---PKLNNHDCRISNIETVIEFQQKNNRL 193 >5R1R-A nrPDB Length = 761 Score = 27.2 bits (59), Expect = 5.2, Method: Composition-based stats. Identities = 26/166 (15%), Positives = 48/166 (28%), Gaps = 41/166 (24%) Query: 37 DAPDYDRSQWLNEKFKL-GLDFPNL--PYLIDGAHKITQSNAILCYIARKHNLCGETEEE 93 DAPDY F L + P L D K+ + ++ + TEEE Sbjct: 73 DAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDY-----TEEE 127 Query: 94 KIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKI 153 ++D + D + ++L + N++ Sbjct: 128 FKQMDTFIDHDRDMTFSYAAV--------------KQLEG------------KYLVQNRV 161 Query: 154 TFVDFLVYDVLDLHRIFEPKCL-DAFP---NLKDFISRFEGLEKIS 195 T +Y+ I CL +P L+ ++ + Sbjct: 162 TG---EIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFK 204 >2OBA-A nrPDB Length = 138 Score = 27.2 bits (59), Expect = 5.4, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 24/67 (35%), Gaps = 6/67 (8%) Query: 87 CGETEEEKIRVDILENQTMDNHMQLGM------ICYNPEFEKLKPKYLEELPEKLKLYSE 140 CG RV I +D H + P +E+L YL ++P SE Sbjct: 44 CGRLHGHSFRVAIHIEGEVDPHTGWIRDFAEIKAIFKPIYEQLDHNYLNDIPGLENPTSE 103 Query: 141 FLGKRPW 147 L + W Sbjct: 104 NLCRWIW 110 >3ADR-A nrPDB Length = 261 Score = 27.2 bits (59), Expect = 5.8, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 27/85 (31%), Gaps = 4/85 (4%) Query: 125 PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRI--FEPKCLDAFP-NL 181 P E+ + E L AG + DF D LD + + P L Sbjct: 13 PVEFPEIATVYVMCGEKL-TVMIDAGVSNSIADFSFLDKLDYIVLTHLHIDHIGLLPELL 71 Query: 182 KDFISRFEGLEKISAYMKSSRFLPR 206 + + ++ Y+ S L + Sbjct: 72 QVYKAKVLVKSGFKKYLTSEDGLKK 96 >3R2G-A nrPDB Length = 361 Score = 27.2 bits (59), Expect = 6.3, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 59/173 (34%), Gaps = 45/173 (26%) Query: 19 LLLEYTDSSYEEKK----YTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSN 74 +++ ++++ Y ++ + + KL L NLP + IT+SN Sbjct: 1 MVMTDQAITFDDVLLVPSYNHHESRRVVETTSTDRLGKLTL---NLPVISANMDTITESN 57 Query: 75 ------------AILCYIARKHNL-------------CGETEEEKIRVDILENQTMDNHM 109 A+ ++ + N+ G TE E R + L + D Sbjct: 58 MANFMHSKGAMGALHRFMTIEENIQEFKKCKGPVFVSVGCTENELQRAEALRDAGADFFC 117 Query: 110 QLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITF--VDFLV 160 + + + + + LK + LG R AGN T+ D+L Sbjct: 118 V-----------DVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVATYAGADYLA 159 >3AGR-A nrPDB Length = 602 Score = 26.8 bits (58), Expect = 6.5, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 38/105 (36%), Gaps = 20/105 (19%) Query: 16 AIRLLLEYTDSSYEEKKYTMGDAPD-YDRSQWLNEKFKLGLDFPNLPYLID---GAHKIT 71 +IRLL + + + D Y W + F ++P + D G ++ Sbjct: 75 SIRLL--GAGKRFAGLRGVLESWLDAYAGEDWESRSVDSKRLFQHVPEMEDSARGLMQLL 132 Query: 72 QSNAILCYIARKHNLCGETEEEKIRVDIL--------ENQTMDNH 108 + +A+ + K TEE+K++V + D H Sbjct: 133 EDDAV-RILDEKL-----TEEQKVQVQAMGVPVLLCSTAGVRDFH 171 >5E1J-A nrPDB Length = 741 Score = 26.8 bits (58), Expect = 6.8, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 10/78 (12%) Query: 131 LPEKLK-----LYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFI 185 LP+ K ++ E R + NK F D L + P + FP + + Sbjct: 360 LPKISKEEFGLIFDELDDTRDFKI-NKDEFADLCQAIALRFQKEEVPSLFEHFPQI--YH 416 Query: 186 SRFEGLEKISAYMKSSRF 203 S ++ A+++S F Sbjct: 417 SALSQ--QLRAFVRSPNF 432 >5Y7I-A nrPDB Length = 261 Score = 26.8 bits (58), Expect = 7.3, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 23/53 (43%), Gaps = 4/53 (7%) Query: 125 PKYLEE-LPEKLKLYS---EFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 YL LPE++ S + R + G+++T D + L + R+ K Sbjct: 161 DDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVIRVAAKK 213 >4G74-A nrPDB Length = 502 Score = 26.8 bits (58), Expect = 7.4, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 36/103 (34%), Gaps = 18/103 (17%) Query: 60 LPYLIDGAHKITQ---SNAILCYIA---RKHNLCGETEEEKIRVDILE------------ 101 +P + D H + + S I A K NL + + E+ R+ + Sbjct: 174 IPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAA 233 Query: 102 NQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGK 144 + D Q E+++ +E LP L ++ + L Sbjct: 234 GELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 276 >2RAS-A nrPDB Length = 212 Score = 26.8 bits (58), Expect = 7.8, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 18/48 (37%) Query: 94 KIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEF 141 + + D + ++P E ++ +LP + K+Y F Sbjct: 45 QANLSRYFETREDLMEAIADYWFHPMVEIMEDVLASDLPPRRKMYEFF 92 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.146 0.410 Lambda K H 0.267 0.0441 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,778,724 Number of Sequences: 36641 Number of extensions: 420547 Number of successful extensions: 1531 Number of sequences better than 10.0: 156 Number of HSP's better than 10.0 without gapping: 180 Number of HSP's successfully gapped in prelim test: 63 Number of HSP's that attempted gapping in prelim test: 1167 Number of HSP's gapped (non-prelim): 251 length of query: 218 length of database: 10,336,785 effective HSP length: 93 effective length of query: 125 effective length of database: 6,929,172 effective search space: 866146500 effective search space used: 866146500 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.5 bits)