BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09210 (222 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2VCT-A nrPDB 448 e-127 1PL2-A nrPDB 424 e-119 3I6A-A nrPDB 405 e-113 2VCV-A nrPDB 399 e-112 5LCZ-A nrPDB 354 2e-98 1F3B-A nrPDB 335 7e-93 1EV4-A nrPDB 318 1e-87 1VF1-A nrPDB 287 2e-78 1B48-A nrPDB 280 4e-76 1GUL-A nrPDB 261 1e-70 2GSR-A nrPDB 97 8e-21 4Q5R-A nrPDB 89 1e-18 1TU7-A nrPDB 88 3e-18 1GSQ-A nrPDB 86 1e-17 4Q5F-A nrPDB 86 1e-17 2GLR-A nrPDB 86 1e-17 5D73-A nrPDB 86 1e-17 18GS-A nrPDB 85 2e-17 2AAW-A nrPDB 84 6e-17 1ZL9-A nrPDB 76 1e-14 3KXO-A nrPDB 74 4e-14 1YQ1-A nrPDB 74 5e-14 5Y9Z-A nrPDB 73 8e-14 5AN1-A nrPDB 72 2e-13 2FHE-A nrPDB 68 3e-12 4Q5Q-A nrPDB 67 9e-12 3GTU-B nrPDB 67 9e-12 2WRT-A nrPDB 64 4e-11 1HNA-A nrPDB 64 6e-11 2HNL-A nrPDB 64 7e-11 2WDU-A nrPDB 60 8e-10 5F07-A nrPDB 58 3e-09 1B8X-A nrPDB 58 3e-09 1BG5-A nrPDB 58 3e-09 1DUG-A nrPDB 58 3e-09 4GTU-A nrPDB 57 5e-09 1XWK-A nrPDB 57 5e-09 2CZ2-A nrPDB 57 7e-09 1FHE-A nrPDB 57 7e-09 1B4P-A nrPDB 55 3e-08 2CA8-A nrPDB 54 4e-08 1M0U-A nrPDB 54 6e-08 1U3I-A nrPDB 53 8e-08 4WR5-A nrPDB 52 3e-07 5FWG-A nrPDB 52 3e-07 4RI7-A nrPDB 50 7e-07 4YH2-A nrPDB 49 2e-06 1GSU-A nrPDB 49 2e-06 5F06-A nrPDB 48 3e-06 2DC5-A nrPDB 48 4e-06 4PNG-A nrPDB 48 4e-06 1FW1-A nrPDB 46 1e-05 1F2E-A nrPDB 45 2e-05 5EY6-A nrPDB 42 2e-04 3LSZ-A nrPDB 41 3e-04 1AXD-A nrPDB 37 0.005 3IBH-A nrPDB 37 0.006 1PN9-A nrPDB 36 0.016 3GH6-A nrPDB 35 0.020 2GDR-A nrPDB 35 0.031 3MAK-A nrPDB 35 0.033 1AW9-A nrPDB 34 0.039 3UBL-A nrPDB 34 0.047 5A5K-A nrPDB 33 0.087 5LOL-A nrPDB 33 0.098 1JLV-A nrPDB 32 0.15 6F05-A nrPDB 32 0.17 4FQU-A nrPDB 32 0.17 3PPU-A nrPDB 31 0.36 3LG6-A nrPDB 31 0.47 5F0G-A nrPDB 31 0.53 5V8F-F nrPDB 30 0.64 5F05-A nrPDB 30 0.67 6GCB-A nrPDB 30 0.89 6GC9-A nrPDB 29 1.4 1BB9-A nrPDB 29 1.7 1MV0-B nrPDB 28 2.4 5ELG-A nrPDB 28 3.1 5WTZ-A nrPDB 28 3.3 1MV3-A nrPDB 28 3.4 3FD5-A nrPDB 28 3.8 3BBY-A nrPDB 28 3.8 2IL3-A nrPDB 28 4.4 3FDD-A nrPDB 27 5.0 2C3Q-A nrPDB 27 5.6 5D9W-A nrPDB 27 6.8 5DXT-A nrPDB 27 7.4 >2VCT-A nrPDB Length = 222 Score = 448 bits (1153), Expect = e-127, Method: Compositional matrix adjust. Identities = 221/222 (99%), Positives = 222/222 (100%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPF+QPEEQDAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 >1PL2-A nrPDB Length = 222 Score = 424 bits (1091), Expect = e-119, Method: Compositional matrix adjust. Identities = 210/222 (94%), Positives = 214/222 (96%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQ RAILNYIASKYNLYGKDIKE+ALIDMYIEGIADLGEMILLLP PEE+DAK Sbjct: 61 DGMKLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 LALI+EK KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEE+RKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222 >3I6A-A nrPDB Length = 222 Score = 405 bits (1040), Expect = e-113, Method: Compositional matrix adjust. Identities = 201/221 (90%), Positives = 207/221 (93%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMYIEGIADLGEMI++LPF PEE+DAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 LALI+EK KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 LKALKTRISNLPTVKKFLQPGSPRKPP DE + IFR Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPPDEIYVRTVYNIFR 221 >2VCV-A nrPDB Length = 222 Score = 399 bits (1025), Expect = e-112, Method: Compositional matrix adjust. Identities = 197/222 (88%), Positives = 208/222 (93%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA KPKLHY N RGRME IRWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMY EG+ADL EMILLLP +PEE+DAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 +ALI+EKTK+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEE+RKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 >5LCZ-A nrPDB Length = 222 Score = 354 bits (908), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 179/222 (80%), Positives = 199/222 (89%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKD+KE+ALIDMY EGI DL EMI+ L P++++AK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 AL +++TKNRY PAFEKVLKSHGQDYLVGN+L+R DIHL+ELL YVEE D+SL++SFPL Sbjct: 121 TALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLLTSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKA K+RIS+LP VKKFLQPGS RKP MD K +EE+RKIFRF Sbjct: 181 LKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARKIFRF 222 >1F3B-A nrPDB Length = 222 Score = 335 bits (860), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 161/220 (73%), Positives = 188/220 (85%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 A KP LHY N RGRME IRWLLAAAGVEFEEKFI+S EDL+KL+ DG LMF QVPMVEID Sbjct: 1 AGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 GMKL QTRAILNYIA+KY+LYGKD+KE+ALIDMY EGI DL EMI L P++++AK Sbjct: 61 GMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKT 120 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 AL +++TKNRY PAFEKVLKSHGQDYLVGN+L+R DIHL+E+L YVEE D+SL++ FPLL Sbjct: 121 ALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 KA K+RIS+LP VKKFLQPGS RKPPMD K ++E+RK F+ Sbjct: 181 KAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFK 220 >1EV4-A nrPDB Length = 221 Score = 318 bits (815), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 162/219 (73%), Positives = 190/219 (86%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGM 63 KP LHY N RGRME IR+LLAAAGVEF+EKFI+S EDL+KL+ DG LMF QVPMVEIDGM Sbjct: 3 KPVLHYFNARGRMECIRFLLAAAGVEFDEKFIQSPEDLEKLKKDGNLMFDQVPMVEIDGM 62 Query: 64 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLAL 123 KL QTRAILNYIA+KY+LYGKD+KE+ALIDMY EGI DL EMI+ L P++++AK AL Sbjct: 63 KLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQKEAKTAL 122 Query: 124 IQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKA 183 +++TKNRY PAFEKVLKSHGQDYLVGNKL+R DIHL+ELL YVEE D+SL++SFPLLKA Sbjct: 123 AKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFDASLLTSFPLLKA 182 Query: 184 LKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 K+RIS+LP VKKFLQPGS RK PMD K +EE+RKI++F Sbjct: 183 FKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARKIYKF 221 >1VF1-A nrPDB Length = 229 Score = 287 bits (735), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 141/221 (63%), Positives = 170/221 (76%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA KP L+Y N RG+MESIRWLLAAAGVEFEE F+++ E +KL G LMFQQVPMVEI Sbjct: 1 MAAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIA KYNLYGKD+KE+ALIDMY+ G DL +L PF E++ + Sbjct: 61 DGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQ 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 A + EK +RYFPA+EKVLK HGQD+LVGN+LS ADIHL+E + VEE S +S FPL Sbjct: 121 CAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKSDALSGFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 L+A K RIS++PT+KKFL PGS RKP D+K +E R++ R Sbjct: 181 LQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRRVLR 221 >1B48-A nrPDB Length = 221 Score = 280 bits (716), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 134/221 (60%), Positives = 171/221 (77%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 A KPKL+Y N RGRMESIRWLLAAAGVEFEE+F+++ E +K++ DG+L+F QVP+VEID Sbjct: 1 AAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 GM L QTRAIL+Y+A+KYNLYGKD+KE+ IDMY +G DL MI + PF P+E++ Sbjct: 61 GMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESY 120 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 LI + K RYFP FEK+LK HG+ +LVGN+LS ADI L+E + VEEL + ++S FPLL Sbjct: 121 DLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 +A KTRISN+PT+KKFLQPGS RKPP D +E R + +F Sbjct: 181 QAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRIVLKF 221 >1GUL-A nrPDB Length = 222 Score = 261 bits (668), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 120/221 (54%), Positives = 173/221 (78%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA +PKLHY N RGRMES+RW+LAAAGVEF+E+F+++ E L KL++ +L+FQQVPMVEI Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTR+IL+YIA K+NL+GK++KE+ LIDMY+EG DL E++++ PF +P++Q + Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + + +K RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ + +EE +++S+FP Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 L+ ++SN+PT+K+FL+PGS +KPP DE + IFR Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221 >2GSR-A nrPDB Length = 207 Score = 96.7 bits (239), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 64/194 (32%), Positives = 105/194 (54%), Gaps = 9/194 (4%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLV 66 + Y +RGR E++R LLA ++E+ + + E L+ +F+Q+P + + L Sbjct: 5 ITYFPVRGRCEAMRMLLADQDQSWKEEVV-TMETWPPLKPS--CLFRQLPKFQDGDLTLY 61 Query: 67 QTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQE 126 Q+ AIL ++ + LYGKD KE AL+DM +G+ DL L ++ E K Sbjct: 62 QSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYTNYEAGKEKYV---- 117 Query: 127 KTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKAL 184 K + FE +L + GQ ++VG+++S AD +L++LL + L+ S + +FPLL A Sbjct: 118 KELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDAFPLLSAY 177 Query: 185 KTRISNLPTVKKFL 198 R+S P +K FL Sbjct: 178 VARLSARPKIKAFL 191 >4Q5R-A nrPDB Length = 204 Score = 89.0 bits (219), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 64/211 (30%), Positives = 111/211 (52%), Gaps = 10/211 (4%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA KL Y ++ E IR+LL+ +FE+ + D L+ + F + P++EI Sbjct: 1 MAPSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEG-DWPNLKPS--MPFGKTPVLEI 57 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE-QDA 119 DG + Q+ AI Y+ ++ L GKD E IDM ++ I+D I + E + Sbjct: 58 DGKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQK 117 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DSSLISSF 178 K ++++T Y F++V+K++G YL KL+ AD + V +L Y+ + L+++ Sbjct: 118 KWDPLKKETIPYYTKKFDEVVKANGG-YLAAGKLTWADFYFVAILDYLNHMAKEDLVANQ 176 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPMD 209 P LKAL+ ++ LP +K ++ ++PP D Sbjct: 177 PNLKALREKVLGLPAIKAWVA----KRPPTD 203 >1TU7-A nrPDB Length = 208 Score = 87.8 bits (216), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 64/209 (30%), Positives = 109/209 (52%), Gaps = 14/209 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL Y +IRG E IR L ++F + I + +D +++ F Q+P + ++ Sbjct: 4 KLTYFSIRGLAEPIRLFLVDQDIKFIDDRI-AKDDFSSIKSQ--FQFGQLPCLYDGDQQI 60 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLG---EMILLLPFSQPEEQDAKLA 122 VQ+ AIL ++A KYNL G++ E IDM+ EG+ DL ++ + + ++ K Sbjct: 61 VQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETEKDPYIKSI 120 Query: 123 LIQEKTKNRYFPAFEKVL--KSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 L E K FEK+L + +G++ ++G+K+S AD L E L + LD + FPL Sbjct: 121 LPGELAK------FEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCLDKFPL 174 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMD 209 LK R+ + P +K++ + K P++ Sbjct: 175 LKVFHQRMKDRPKLKEYCEKRDAAKVPVN 203 >1GSQ-A nrPDB Length = 202 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 58/195 (29%), Positives = 100/195 (51%), Gaps = 6/195 (3%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLV 66 LHY + GR E R++LAA G EF ++ ++ A D L+ Y +P+++IDG K+ Sbjct: 5 LHYFPLMGRAELCRFVLAAHGEEFTDRVVEMA-DWPNLKATMY--SNAMPVLDIDGTKMS 61 Query: 67 QTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQE 126 Q+ I ++A ++ L GK EK +D E + D+ ++ + F+ PE + E Sbjct: 62 QSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFA-PEAAKEAVQQNYE 120 Query: 127 KTKNRYFPAFEKVLKSHG--QDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKAL 184 K+ R P E +L S+G + VGN ++ AD+H L + L+ P + AL Sbjct: 121 KSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPKIVAL 180 Query: 185 KTRISNLPTVKKFLQ 199 + R++ P + +L+ Sbjct: 181 RKRVAECPKIAAYLK 195 >4Q5F-A nrPDB Length = 218 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 60/204 (29%), Positives = 104/204 (50%), Gaps = 9/204 (4%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL Y +IRG E R + AGV+FE+ +K ED L+ F Q+P++E+DG L Sbjct: 17 KLTYFDIRGLGEGARLIFHQAGVKFEDNRLKR-EDWPALKPK--TPFGQLPLLEVDGEVL 73 Query: 66 VQTRAILNYIASKYNLYGKDIKEKA----LIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 Q+ AI Y+ ++ L GK E+A + D + + +A+L +L + +++ L Sbjct: 74 AQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKEKVL 133 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 + ++++ P EK L G +Y+VG ++ AD+ + + L E L +S L Sbjct: 134 KEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFLSGHLQL 193 Query: 182 KALKTRISNLPTVKKFL--QPGSP 203 K + LP +KK++ +P +P Sbjct: 194 KKYIEHVRELPNIKKWIAERPKTP 217 >2GLR-A nrPDB Length = 209 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 62/199 (31%), Positives = 100/199 (50%), Gaps = 21/199 (10%) Query: 9 YSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQT 68 Y +RGR E++R LLA G ++E+ + + L L + Q+P E + L Q+ Sbjct: 7 YFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCL-YGQLPKFEDGDLTLYQS 65 Query: 69 RAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKT 128 AIL ++ LYGK+ +E A +DM +G+ DL + L ++ E Sbjct: 66 NAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTN-----------YENG 114 Query: 129 KNRYFPA-------FEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179 KN Y A FE +L + G+ ++VG+++S AD +L++LL + L + +FP Sbjct: 115 KNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFP 174 Query: 180 LLKALKTRISNLPTVKKFL 198 LL A R+S P +K FL Sbjct: 175 LLSAYVARLSARPKIKAFL 193 >5D73-A nrPDB Length = 208 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/207 (30%), Positives = 109/207 (52%), Gaps = 10/207 (4%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL Y IRG E IR +L G++F + I +A D +++ + F Q+P + ++ Sbjct: 4 KLTYFPIRGLAEPIRLVLVDQGIKFTDDRI-NASDWPSMKS--HFHFGQLPCLYDGDHQI 60 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPF-SQPEEQDAKLALI 124 VQ+ AIL ++A K+NL G + E IDM+ EG+ DL + + + E+D+ + I Sbjct: 61 VQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYDTEKDSYIKDI 120 Query: 125 QEKTKNRYFPAFEKVL--KSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182 FEK+L + G+++++G K+S D L E L + LD + FPLLK Sbjct: 121 LPVE----LAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCLDKFPLLK 176 Query: 183 ALKTRISNLPTVKKFLQPGSPRKPPMD 209 A R+ + P +K++ + + K P++ Sbjct: 177 AYHQRMEDRPGLKEYCKQRNRAKIPVN 203 >18GS-A nrPDB Length = 210 Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 59/193 (30%), Positives = 102/193 (52%), Gaps = 9/193 (4%) Query: 9 YSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQT 68 Y +RGR ++R LLA G ++E+ + + E + ++ Q+P + + L Q+ Sbjct: 8 YFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGDLTLYQS 66 Query: 69 RAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE-QDAKLALIQEK 127 IL ++ LYGKD +E AL+DM +G+ DL + L ++ E +D + + + Sbjct: 67 NTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQ 126 Query: 128 TKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALK 185 K FE +L + G+ ++VG+++S AD +L++LL E L + +FPLL A Sbjct: 127 LK-----PFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181 Query: 186 TRISNLPTVKKFL 198 R+S P +K FL Sbjct: 182 GRLSARPKLKAFL 194 >2AAW-A nrPDB Length = 222 Score = 83.6 bits (205), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 62/210 (29%), Positives = 105/210 (50%), Gaps = 19/210 (9%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAED----LDKLRNDGYLMFQQVP 56 M + L+Y + RG+ E IR + A G+E+ +K D + + F+QVP Sbjct: 12 MGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVP 71 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPE- 115 +++I + L Q++AI+ Y++ KYN+ G+ + DM G+ D+ F+ Sbjct: 72 ILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIH-----YKFNNTNL 126 Query: 116 -EQDAKLALIQEKTKNRYFPAFEKVLKSHGQD------YLVGNKLSRADIHLVELLYYVE 168 +Q+ L ++ K + FEK+LK + + Y VGN L+ AD+ + L +E Sbjct: 127 FKQNETTFLNEDLPK--WSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIE 184 Query: 169 ELDSSLISSFPLLKALKTRISNLPTVKKFL 198 S + +FPLLKA ISNLP +K ++ Sbjct: 185 TKYPSSLKNFPLLKAHNEFISNLPNIKNYI 214 >1ZL9-A nrPDB Length = 207 Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/210 (28%), Positives = 98/210 (46%), Gaps = 30/210 (14%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL Y N RG E R + A AG ++E+ + + E L+ F Q+P +E+DG KL Sbjct: 5 KLTYFNGRGAGEVSRQIFAYAGQQYEDNRV-TQEQWPALKETCAAPFGQLPFLEVDGKKL 63 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGE-----MILLLPFSQPEEQDAK 120 Q+ AI ++A ++ L GK E+A ++ + D ++ F + + K Sbjct: 64 AQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPGDVETLK 123 Query: 121 LALIQEKTKNRYFPAFEK-------VLKSHGQDYLVGNKLSRADI----HLVELLYYVEE 169 K+ + PAFEK LK+ G +LVG+ L+ D+ H +L+ Sbjct: 124 --------KDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSADLI----- 170 Query: 170 LDSSLISSFPLLKALKTRISNLPTVKKFLQ 199 S FP LKA +I +P +KK+++ Sbjct: 171 AKGGDFSKFPELKAHAEKIQAIPQIKKWIE 200 >3KXO-A nrPDB Length = 202 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 54/204 (26%), Positives = 108/204 (52%), Gaps = 16/204 (7%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL Y N+RGR E IR++ A +++E+ I+ A D ++++ L F ++P++E+DG+ L Sbjct: 8 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEVDGLTL 64 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQ 125 Q+ AI Y+ +L G E+ +D ++ + D + P+++ ++QD K + Sbjct: 65 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDF---MSCFPWAE-KKQDVKEQMFN 120 Query: 126 E-KTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182 E T N P + L ++ G+++L+GN ++ AD + + L+ + P L Sbjct: 121 ELLTYNA--PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLV 178 Query: 183 ALKTRISNLPTVKKFLQPGSPRKP 206 L+ ++ +P V +++ R+P Sbjct: 179 TLRKKVQAIPAVANWIK----RRP 198 >1YQ1-A nrPDB Length = 208 Score = 73.9 bits (180), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 17/203 (8%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL Y RG E IR L AGV+FEE ++ D L +Q+P++ IDG +L Sbjct: 5 KLTYFFFRGLGEPIRLLFHLAGVQFEE--VRMNPDQTWLDIKDSTPMKQLPVLNIDGFEL 62 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQ--PEEQDAKLAL 123 Q+ AIL Y+A K+ GK +E+A +D + D L F + E + K A Sbjct: 63 PQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKD-----FLAEFKKFAAERRSGKSAE 117 Query: 124 IQEK--------TKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI 175 EK +N YF +L+ +L+G+ ++ AD+ +V+ L ++ Sbjct: 118 EVEKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGLFDE 177 Query: 176 SSFPLLKALKTRISNLPTVKKFL 198 S F L AL+ ++++ P +K+++ Sbjct: 178 SEFTKLAALREKVNSYPGIKEYI 200 >5Y9Z-A nrPDB Length = 199 Score = 73.2 bits (178), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 104/199 (52%), Gaps = 18/199 (9%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL Y N+RGR E IR++ A +++E+ I+ A D K++ L F ++P++E++G+ L Sbjct: 5 KLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQA-DWPKIKPT--LPFGKIPVLEVEGLTL 61 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQ 125 Q+ AI Y+ +L GK E+ +D ++ + D + L P+++ E QD K Sbjct: 62 HQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDF---MSLFPWAE-ENQDLK----- 112 Query: 126 EKTKN----RYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179 E+T N R P K L ++ D + +GN ++ AD + + L L+ +P Sbjct: 113 ERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYP 172 Query: 180 LLKALKTRISNLPTVKKFL 198 L +L+ ++ +P + ++ Sbjct: 173 RLVSLRNKVQAIPAISAWI 191 >5AN1-A nrPDB Length = 219 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 61/215 (28%), Positives = 98/215 (45%), Gaps = 16/215 (7%) Query: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK-----LRNDGYLMFQQVPM 57 P L Y R + IR +L G EFEEK + A D DK ++ L F +P Sbjct: 3 PVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPY 62 Query: 58 VEIDG-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE 116 IDG +K+ Q++AI+ Y+A K+ L G +E DM + D+ E + + E+ Sbjct: 63 Y-IDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHYEQ 121 Query: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS 176 +DA A + K + + L S + + G+KL+ D E+ LD + + Sbjct: 122 KDAYTASLPAKLRQ-----YSDFLGS--RPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLD 174 Query: 177 SFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEK 211 F L+A + R +L +KK++ K P+ K Sbjct: 175 GFKNLQAFQKRFEDLEAIKKYMASPKFLKKPICNK 209 >2FHE-A nrPDB Length = 216 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 63/210 (30%), Positives = 104/210 (49%), Gaps = 15/210 (7%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEIDG 62 KL Y IRG + +R LL G ++EE+ I +D +K + + L +P D Sbjct: 3 KLGYWKIRGLQQPVRLLLEYLGEKYEEQ-IYERDDGEKWFSKKFELGLDLPNLPYYIDDK 61 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIA-DLGEMILLLPFSQPEEQDAKL 121 KL Q+ AIL YIA K+ + G +E+A + M IEG A DL + I + + QP+ + K Sbjct: 62 CKLTQSLAILRYIADKHGMIGTTSEERARVSM-IEGAAVDLRQGISRISY-QPKFEQLKE 119 Query: 122 ALIQEKTKNRYFPAFEKVLKSH-GQD-YLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179 +++ P K+ G++ YL G +S D + E L + L+ + FP Sbjct: 120 GYLKD------LPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFP 173 Query: 180 LLKALKTRISNLPTVKKFLQPGSPRKPPMD 209 L+ +RI LP++K +++ K P++ Sbjct: 174 NLQQFMSRIEALPSIKAYMESNRFIKWPLN 203 >4Q5Q-A nrPDB Length = 219 Score = 66.6 bits (161), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 63/214 (29%), Positives = 99/214 (46%), Gaps = 24/214 (11%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVP 56 +P L Y +IRG + IR LL +GV+F +K I A D D+ N+ + L F +P Sbjct: 3 QPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLP 62 Query: 57 MVEIDG-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPE 115 IDG MK+ QT AIL Y+ KY L G + E+ I M + D+ ++ + + Sbjct: 63 YY-IDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCY---- 117 Query: 116 EQDAKLALIQEKTKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEEL 170 DA +K K Y + LK ++ G +S D +L E L +V+ + Sbjct: 118 --DANC----DKLKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVM 171 Query: 171 DSSLISSFPLLKALKTRISNLPTVKKFLQPGSPR 204 + F LK R+ +LP V +++ P+ Sbjct: 172 VPEVFGQFENLKRYVERMESLPRVSDYIKKQQPK 205 >3GTU-B nrPDB Length = 224 Score = 66.6 bits (161), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 62/225 (27%), Positives = 92/225 (40%), Gaps = 24/225 (10%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59 L Y +IRG +IR LL +EEK E D R+ L F +P + Sbjct: 8 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 66 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 +DG K+ Q+ AIL YIA K+N+ G+ +EK +D+ + D ++ L +S Sbjct: 67 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSD---- 122 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 EK K +Y LK + G KL+ D ++L D Sbjct: 123 ------HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 176 Query: 174 LISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 + FP LKA R L + +LQ K P++ K + K Sbjct: 177 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >2WRT-A nrPDB Length = 218 Score = 63.9 bits (154), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 60/199 (30%), Positives = 94/199 (47%), Gaps = 13/199 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI---DG 62 KL Y IRG + +R LL E E+ + +D +K D + M +P + D Sbjct: 4 KLGYWKIRGLQQPVR-LLLEYLGEEYEEHLYGRDDREKWLGDKFNMGLDLPNLPYYIDDK 62 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 KL Q+ AI+ YIA K+ + G +E+A I M IEG A M + P+ ++ K Sbjct: 63 CKLTQSVAIMRYIADKHGMLGSTPEERARISM-IEGAAMDLRMGFVRVCYNPKFEEVKGD 121 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 ++E P K+ + D YL G+ +S D + E L + L + FP Sbjct: 122 YLKE------LPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPK 175 Query: 181 LKALKTRISNLPTVKKFLQ 199 LK K+RI +LP +K +++ Sbjct: 176 LKEFKSRIEDLPKIKAYME 194 >1HNA-A nrPDB Length = 217 Score = 63.5 bits (153), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 65/208 (31%), Positives = 98/208 (47%), Gaps = 28/208 (13%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 L Y NIRG SIR LL +EEK + A D D+ + N+ + L F +P + Sbjct: 4 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 IDG K+ Q+ AIL YIA K+NL G+ KE+ + E IL F Q Sbjct: 63 IDGTHKITQSNAILRYIARKHNLCGESEKEQ------------IREDILENQFMDSRMQL 110 Query: 119 AKLALIQ--EKTKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELD 171 AKL EK K Y A ++LK + Q + +G+K++ D ++L + + Sbjct: 111 AKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFE 170 Query: 172 SSLISSFPLLKALKTRISNLPTVKKFLQ 199 S + +FP LK +R L + +++ Sbjct: 171 PSCLDAFPNLKDFISRFEGLEKISAYMK 198 >2HNL-A nrPDB Length = 225 Score = 63.5 bits (153), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 58/201 (28%), Positives = 99/201 (49%), Gaps = 12/201 (5%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAE-DLDKLRNDGYLMFQQVPMVEID 61 EK L Y N RGR E IR L A A V +E+ I E K R F VPM+ + Sbjct: 26 EKYTLTYFNGRGRAEVIRLLFALANVSYEDNRITRDEWKYLKPRTP----FGHVPMLNVS 81 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 G L ++ AI + ++ L G + E+A I + I +L + L+P++ + K Sbjct: 82 GNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQK--LIPWTHEKNTTKKA 139 Query: 122 ALIQEKTKNRYFP---AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L + +++ P +EK LK ++VGNK+S AD+ + +L ++ D + + Sbjct: 140 ELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLD--DEVKLEEY 197 Query: 179 PLLKALKTRISNLPTVKKFLQ 199 P L + +I +P +K++++ Sbjct: 198 PQLASFVNKIGQMPGIKEWIK 218 >2WDU-A nrPDB Length = 211 Score = 60.1 bits (144), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 17/198 (8%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEE-KFIKSAEDLDKLRNDGYLMFQQVPMVEIDG-- 62 KL Y RGR E IR LL AGV+FE+ +F K G +VP++++ G Sbjct: 7 KLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPTIKPTLPG----GRVPLLDVTGPD 62 Query: 63 ---MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPE-EQD 118 + ++ AI +A ++ + G+ +E LI+ I DL + + F P+ E++ Sbjct: 63 GKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTI-FRTPQGEKE 121 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYV-EELDSSLISS 177 AK+ +E + L+S G ++ GN+++ D+ L L +V E + L Sbjct: 122 AKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVPGFLEQK 181 Query: 178 FPLL----KALKTRISNL 191 FP L K+L T S L Sbjct: 182 FPKLHEFHKSLPTSCSRL 199 >5F07-A nrPDB Length = 213 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 50/162 (30%), Positives = 78/162 (48%), Gaps = 16/162 (9%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKY-----NLYGKDIKEKALIDMYIEGIA-DLGEM 105 F QVP+VE KL ++RAI+ Y A+KY NL G ++EKAL+D ++E A + ++ Sbjct: 50 FGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDL 109 Query: 106 ILLLPFSQ------PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADI- 158 + + F ++ D++L E+ + +EK L YL G+ + AD+ Sbjct: 110 VFNIVFQVVILPRIGQQGDSELVRTYEEKLEKVLDVYEKRLSK--SKYLAGDSFTLADLS 167 Query: 159 HLVELLYYVEELD-SSLISSFPLLKALKTRISNLPTVKKFLQ 199 HL Y V E L+ L A IS+ P KK + Sbjct: 168 HLPATRYLVNEAGLGHLVKDRKKLNAWWEDISSRPAWKKLMN 209 >1B8X-A nrPDB Length = 280 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 15/201 (7%) Query: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEID 61 P L Y I+G ++ R LL ++EE + E DK RN + L F +P ID Sbjct: 2 PILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-DKWRNKKFELGLEFPNLPYY-ID 59 Query: 62 G-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE--QD 118 G +KL Q+ AI+ YIA K+N+ G KE+A I M + D+ + + +S+ E + Sbjct: 60 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKV 119 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L+ + E K FE L + YL G+ ++ D L + L V +D + +F Sbjct: 120 DFLSKLPEMLK-----MFEDRLCH--KTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAF 172 Query: 179 PLLKALKTRISNLPTVKKFLQ 199 P L K RI +P + K+L+ Sbjct: 173 PKLVCFKKRIEAIPQIDKYLK 193 >1BG5-A nrPDB Length = 254 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 60/201 (29%), Positives = 97/201 (48%), Gaps = 15/201 (7%) Query: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEID 61 P L Y I+G ++ R LL ++EE + E DK RN + L F +P ID Sbjct: 3 PILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-DKWRNKKFELGLEFPNLPYY-ID 60 Query: 62 G-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 G +KL Q+ AI+ YIA K+N+ G KE+A I M + D+ + + +S+ E K Sbjct: 61 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFET-LK 119 Query: 121 LALIQEKTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 + + + P K+ + + YL G+ ++ D L + L V +D + +F Sbjct: 120 VDFLSK------LPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAF 173 Query: 179 PLLKALKTRISNLPTVKKFLQ 199 P L K RI +P + K+L+ Sbjct: 174 PKLVCFKKRIEAIPQIDKYLK 194 >1DUG-A nrPDB Length = 234 Score = 57.8 bits (138), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 15/201 (7%) Query: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEID 61 P L Y I+G ++ R LL ++EE + E DK RN + L F +P ID Sbjct: 2 PILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-DKWRNKKFELGLEFPNLPYY-ID 59 Query: 62 G-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE--QD 118 G +KL Q+ AI+ YIA K+N+ G KE+A I M + D+ + + +S+ E + Sbjct: 60 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKV 119 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L+ + E K FE L + YL G+ ++ D L + L V +D + +F Sbjct: 120 DFLSKLPEMLK-----MFEDRLCH--KTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAF 172 Query: 179 PLLKALKTRISNLPTVKKFLQ 199 P L K RI +P + K+L+ Sbjct: 173 PKLVCFKKRIEAIPQIDKYLK 193 >4GTU-A nrPDB Length = 217 Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 56/202 (27%), Positives = 99/202 (49%), Gaps = 16/202 (7%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 L Y +IRG +IR LL +EEK + A D D+ + N+ + L F +P + Sbjct: 4 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 IDG K+ Q+ AIL YIA K+NL G+ +EK +D+ D+ + + +S P+ + Sbjct: 63 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYS-PDFEK 121 Query: 119 AKLALIQE-KTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 K ++E T ++F F + + VG+K++ D ++L + + + + Sbjct: 122 LKPEYLEELPTMMQHFSQFLG-----KRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDA 176 Query: 178 FPLLKALKTRISNLPTVKKFLQ 199 FP LK +R L + +++ Sbjct: 177 FPNLKDFISRFEGLEKISAYMK 198 >1XWK-A nrPDB Length = 218 Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 59/206 (28%), Positives = 95/206 (46%), Gaps = 24/206 (11%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 L Y +IRG +IR LL +EEK + A D D+ + N+ + L F +P + Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 IDG K+ Q+ AIL YIA K+NL G+ +EK +D+ D M L + PE Sbjct: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE--- 119 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 EK K +Y + LK + + + GNK++ D + ++L + Sbjct: 120 ------FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 Query: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199 + +FP LK +R L + +++ Sbjct: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 >2CZ2-A nrPDB Length = 223 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 60/217 (27%), Positives = 100/217 (46%), Gaps = 22/217 (10%) Query: 2 AEKPKLHYSNIRGRME-SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPM 57 A KP L YS R +R LA G+++E I +D + + + +QVP Sbjct: 10 AGKPIL-YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 68 Query: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALI----DMYIEGIADLGEMILLLP 110 ++IDG+ +VQ+ AI+ Y+ L +D +++A++ D+ GI L + +L Sbjct: 69 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 128 Query: 111 FSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL 170 Q E + A +K F A EK+L+S Y VG+++S AD+ LV + E Sbjct: 129 VGQ--ENQMQWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF 183 Query: 171 DSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 L S +P + + + L + Q PR+ P Sbjct: 184 KVDL-SPYPTISHINKELLAL----EVFQVSHPRRQP 215 >1FHE-A nrPDB Length = 217 Score = 56.6 bits (135), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 59/199 (29%), Positives = 93/199 (46%), Gaps = 13/199 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI---DG 62 KL Y +RG + +R L E E+ + +D +K ++ + M +P + D Sbjct: 3 KLGYWKLRGLAQPVR-LFLEYLGEEYEEHLYGRDDREKWMSEKFNMGLDLPNLPYYIDDK 61 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 KL Q+ AI+ YIA K+ + G +E+A I M IEG A M L + F + + K Sbjct: 62 CKLTQSVAIMRYIADKHGMLGTTPEERARISM-IEGAA----MDLRIGFGR-VCYNPKFE 115 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 ++E+ P K+ D YL G+ +S D L E L + L + FP Sbjct: 116 EVKEEYVKE-LPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPK 174 Query: 181 LKALKTRISNLPTVKKFLQ 199 LK K+RI LP +K +++ Sbjct: 175 LKEFKSRIEALPKIKAYME 193 >1B4P-A nrPDB Length = 217 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 95/208 (45%), Gaps = 24/208 (11%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 L Y N+RG IR LL +EEK + A D D+ + N+ + L F +P + Sbjct: 4 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 IDG K+ Q+ AI+ Y+A K++L G+ +E+ +D+ D + ++ +S P+ Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYS-PD--- 118 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELDSS 173 E+ K Y + +K + Q + GNK++ D + ++L + Sbjct: 119 ------FERKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPK 172 Query: 174 LISSFPLLKALKTRISNLPTVKKFLQPG 201 + +FP LK R L + +++ G Sbjct: 173 CLDAFPNLKDFVARFEGLKKISDYMKSG 200 >2CA8-A nrPDB Length = 211 Score = 54.3 bits (129), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 18/205 (8%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMK- 64 K+ Y N RGR ESIR L AAGV +E++ I S +D K++ + ++P V+I Sbjct: 7 KVIYFNGRGRAESIRMTLVAAGVNYEDERI-SFQDWPKIKPT--IPGGRLPAVKITDNHG 63 Query: 65 ----LVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 +V++ AI Y+A K+++ G +E ++ I DL E +PEE+ K Sbjct: 64 HVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDL-EHEYYKTLMKPEEEKQK 122 Query: 121 LALIQEKTKNRYFPAFEKV----LKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS 176 I ++ N P + LK+ VG+K++ AD+ L+ ++ +V +LD ++ Sbjct: 123 ---IIKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLT 179 Query: 177 S-FP-LLKALKTRISNLPTVKKFLQ 199 +P + K + +++ P + K+L Sbjct: 180 GKYPEIHKHRENLLASSPRLAKYLS 204 >1M0U-A nrPDB Length = 249 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 43/196 (21%), Positives = 98/196 (50%), Gaps = 8/196 (4%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLV 66 L Y N++ E +R+L A E+E+ + + ++ L+ + Q+P++E+DG ++ Sbjct: 52 LFYFNVKALAEPLRYLFAYGNQEYEDVRV-TRDEWPALKPT--MPMGQMPVLEVDGKRVH 108 Query: 67 QTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQ--DAKLALI 124 Q+ ++ ++A L G E ID+ ++ I D I ++ + +PE++ + KL + Sbjct: 109 QSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSY-EPEDEIKEKKLVTL 167 Query: 125 QEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DSSLISSFPLLKA 183 + Y E+ +K + +G KL+ AD++ + Y+ + L+ +P L+ Sbjct: 168 NAEVIPFYLEKLEQTVKDNDGHLALG-KLTWADVYFAGITDYMNYMVKRDLLEPYPALRG 226 Query: 184 LKTRISNLPTVKKFLQ 199 + ++ L +K +++ Sbjct: 227 VVDAVNALEPIKAWIE 242 >1U3I-A nrPDB Length = 211 Score = 53.1 bits (126), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 56/213 (26%), Positives = 113/213 (53%), Gaps = 16/213 (7%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 E K+ Y + RGR ESIR L AAGV++E++ I S +D K++ + ++P V++ Sbjct: 3 GEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERI-SFQDWPKIKPT--IPGGRLPAVKVT 59 Query: 62 GMK-----LVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE 116 ++++ AI Y+A K+++ G+ +E ++ I G A+ E +P+E Sbjct: 60 DDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLI-GQAEDVEHEYHKTLMKPQE 118 Query: 117 QDAKLA--LIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 + K+ ++ K + E + S G+ VG+K++ AD+ L+ ++ +V +LD Sbjct: 119 EKEKITKEILNGKVPVLFNMICESLKGSTGK-LAVGDKVTLADLVLIAVIDHVTDLDKGF 177 Query: 175 ISS-FP-LLKALKTRISNLPTVKKFL--QPGSP 203 ++ +P + K + +++ P + K+L +P +P Sbjct: 178 LTGKYPEIHKHRENLLASSPRLAKYLSNRPATP 210 >4WR5-A nrPDB Length = 244 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/202 (29%), Positives = 97/202 (48%), Gaps = 11/202 (5%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMV 58 + P L Y I+G ++ R LL ++EE + E DK RN + L F +P Sbjct: 24 SXSPILGYWKIKGLVQPTRLLLEXLEEKYEEHLXERDEG-DKWRNKKFELGLEFPNLP-Y 81 Query: 59 EIDG-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQ 117 IDG +KL Q+ AI+ IA K+N+ G KE+A I M + D+ + + +S+ E Sbjct: 82 XIDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFET 141 Query: 118 DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 K+ + + + FE L H + L G+ ++ D L + L V +D + + Sbjct: 142 -LKVDFLSKLPE--MLKMFEDRL-CH-KTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDA 196 Query: 178 FPLLKALKTRISNLPTVKKFLQ 199 FP L K RI +P + K+L+ Sbjct: 197 FPKLVCFKKRIEAIPQIDKYLK 218 >5FWG-A nrPDB Length = 217 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 58/223 (26%), Positives = 100/223 (44%), Gaps = 20/223 (8%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 L Y N+RG IR LL +EEK + A D D+ + N+ + L F +P + Sbjct: 4 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 IDG K+ Q+ AI+ Y+A K++L G+ +E+ D+ + D M L++ P+ + Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMD-NRMQLIMLCYNPDFEK 121 Query: 119 AK---LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI 175 K L I EK K + + L + + G+K++ D ++L + + Sbjct: 122 QKPEFLKTIPEKMK-----LYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 174 Query: 176 SSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 +FP LK R L + +++ P+ K + S K Sbjct: 175 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >4RI7-A nrPDB Length = 215 Score = 50.1 bits (118), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 53/165 (32%), Positives = 79/165 (47%), Gaps = 24/165 (14%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKY------NLYGKDIKEKALIDMYIEGIADL--- 102 F QVP + + + L ++RAI YI KY +LYG DI KA ID ++E Sbjct: 53 FGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGP 112 Query: 103 --GEMILLLPFSQ-PEEQDAKLALIQEKTKN--RYFPAFEKVLKSHGQD-YLVGNKLSRA 156 G+++ L FS P ++ ALI++ + +E+ L GQ +L G++ S A Sbjct: 113 PSGDLVHDLLFSSVPVDE----ALIKKNVDKLAKVLDIYEQKL---GQTRFLAGDEFSFA 165 Query: 157 DI-HLVELLYYVEELDSS-LISSFPLLKALKTRISNLPTVKKFLQ 199 D+ HL Y V D L +S + T ISN + KK L+ Sbjct: 166 DLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLE 210 >4YH2-A nrPDB Length = 222 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 45/156 (28%), Positives = 71/156 (45%), Gaps = 28/156 (17%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKYN----LYGKDIKEKALIDMYIE---GIADLGEM 105 VP +E DG + + AI+ Y+ SKY LY KD ++A++D + G+ Sbjct: 53 HTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVV----- 107 Query: 106 ILLLPFSQPEEQDAKLALIQEKTK---NRY------FPAFEKVLKSHGQDYLVGNKLSRA 156 F+ +K L Q +TK RY + E LK GQDY+ GN+L+ A Sbjct: 108 -----FANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLK--GQDYIAGNQLTIA 160 Query: 157 DIHLVELLYYVEELDSSLISSFPLLKALKTRISNLP 192 D LV + +E + + +P + A ++ LP Sbjct: 161 DFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLP 196 >1GSU-A nrPDB Length = 219 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 61/214 (28%), Positives = 92/214 (42%), Gaps = 22/214 (10%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY-------LMFQQVPMVE 59 L Y +IRG +IR LL ++E+ K+ D +D L F +P + Sbjct: 4 LGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPYL- 62 Query: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 IDG +KL Q+ AIL YIA K+N+ G+ EK +D+ + DL L +S E+ Sbjct: 63 IDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEKL 122 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L Q K R F L S + + VG+KL+ D L Y V + + Sbjct: 123 KPAYLEQLPGKLRQLSRF---LGS--RSWFVGDKLTFVDF----LAYDVLDQQRMFVPDC 173 Query: 179 PLLKA----LKTRISNLPTVKKFLQPGSPRKPPM 208 P L+ R L + +++ G K P+ Sbjct: 174 PELQGNLSQFLQRFEALEKISAYMRSGRFMKAPI 207 >5F06-A nrPDB Length = 216 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 45/164 (27%), Positives = 78/164 (47%), Gaps = 26/164 (15%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKD------IKEKALIDMYIE-------- 97 F Q+P +E D + L ++RAI +YIA K+ G D +KE A + ++ E Sbjct: 50 FGQIPALEEDDLTLFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNP 109 Query: 98 GIADLGEMILLLPF--SQPEEQDAKLALIQEKTK--NRYFPAFEKVLKSHGQDYLVGNKL 153 IA + ++ P + P++ +I + + + +E L S YL G+ Sbjct: 110 AIAPIVFQFMVAPLRGNSPDQ-----TIIDDNVEKLGKVLDIYEAKLSS--TKYLAGDFY 162 Query: 154 SRADIHLVELLYYVEELD-SSLISSFPLLKALKTRISNLPTVKK 196 S AD+H + YY+ + +S+++ P +KA IS+ P KK Sbjct: 163 SLADLHHLPYTYYLMKTPAASVVNERPHVKAWWEDISSRPAFKK 206 >2DC5-A nrPDB Length = 231 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 52/208 (25%), Positives = 94/208 (45%), Gaps = 28/208 (13%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 L Y +IRG +IR L +EEK + A D D+ + N+ + L F +P + Sbjct: 12 LGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYL- 70 Query: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 IDG K+ Q+ AIL Y+ K+NL G+ +E+ +D+ + D M+L Sbjct: 71 IDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMD-NRMVL----------- 118 Query: 119 AKLALIQ--EKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELD 171 A+L EK K Y +++ + + + G+K++ D ++L + + Sbjct: 119 ARLCYNADFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFE 178 Query: 172 SSLISSFPLLKALKTRISNLPTVKKFLQ 199 + + +FP LK R L + +++ Sbjct: 179 AKCLDAFPNLKDFIARFEGLKKISDYMK 206 >4PNG-A nrPDB Length = 229 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 8/146 (5%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY----NLYGKDIKEKALIDMYIEGIADLGEMILL 108 VP +E DG + + AI+ Y+ SKY +LY KD+ ++A++D + + + L Sbjct: 59 HTVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANAL 118 Query: 109 LPFSQPEEQDAKLALIQEKTKN--RYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYY 166 ++P + + +E+ + EK L G DY+ GN+L+ AD ++ + Sbjct: 119 RSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLA--GNDYVAGNQLTIADFSIISTVSS 176 Query: 167 VEELDSSLISSFPLLKALKTRISNLP 192 +E + +P + A R+ LP Sbjct: 177 LEVFVKVDTTKYPRIAAWFKRLQKLP 202 >1FW1-A nrPDB Length = 216 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 10/194 (5%) Query: 2 AEKPKLHYSNIRGRME-SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPM 57 A KP L YS R +R LA G++++ I +D + + + +QVP Sbjct: 3 AGKPIL-YSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPT 61 Query: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQP 114 ++IDG+ + Q+ AI+ Y+ L +D K++A + M + IA + + L + Sbjct: 62 LKIDGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQ 121 Query: 115 EEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 ++ +L Q F A E++L+S Y VG++++ AD+ LV + E L Sbjct: 122 VGEEMQLTWAQNAITCG-FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180 Query: 175 ISSFPLLKALKTRI 188 + +P + ++ R+ Sbjct: 181 -TPYPTISSINKRL 193 >1F2E-A nrPDB Length = 201 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 49/177 (27%), Positives = 79/177 (44%), Gaps = 15/177 (8%) Query: 28 VEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID-GMKLVQTRAILNYIASKYNLYGKDI 86 V+ + ++ ED + G +VP + +D G L + AIL YIA + G Sbjct: 30 VDLAVRKTEAGEDFLTVNPSG-----KVPALTLDSGETLTENPAILLYIADQNPASGLAP 84 Query: 87 KEKALIDMY--IEGIADLGEMI--LLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKS 142 E +L D Y + ++ LG +P P D A E KN + A +K L Sbjct: 85 AEGSL-DRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKN-HLAALDKELA- 141 Query: 143 HGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQ 199 G+D+ GN S ADI+L +L + + + +++P L A +I+ P V L+ Sbjct: 142 -GRDHYAGNAFSVADIYLYVMLGWPAYVGIDM-AAYPALGAYAGKIAQRPAVGAALK 196 >5EY6-A nrPDB Length = 217 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 19/164 (11%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKY------NLYGKDIKEKALIDMYIEGIA----- 100 F QVP + + + L ++R+I Y+ KY LYG + E+A ID ++E Sbjct: 52 FGQVPAFQDESISLFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGP 111 Query: 101 DLGEMILLLPFSQPE---EQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRAD 157 G ++ L F+ P QD + E+ + +E+ L +L G++ + AD Sbjct: 112 SSGALVFQLAFA-PRMNIPQDQGVIKQNEEKLGKVLDIYEQRLGE--SRFLAGDEFTFAD 168 Query: 158 I-HLVELLYYVEELD-SSLISSFPLLKALKTRISNLPTVKKFLQ 199 + HL Y V D L +S + IS+ + KK ++ Sbjct: 169 LSHLPNGDYLVNATDKGHLFTSRENVGRWWNEISDRESWKKVIE 212 >3LSZ-A nrPDB Length = 225 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 87/212 (41%), Gaps = 25/212 (11%) Query: 9 YSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLD---------KLRNDGYLMFQ---QVP 56 Y R R WLLA + FE + A + + YL Q+P Sbjct: 6 YGVYRSRASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPLGQIP 65 Query: 57 MVEIDGMKLVQTRAILNYIASKYN--LYGKDIKEKALIDMY-------IEGIADLGEMIL 107 +E +G+ L ++ AI +IA L + E AL+ + +E A ++I Sbjct: 66 CLEEEGLILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQ 125 Query: 108 LLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYV 167 E A +A+ E+ + R E+ + +DYLVG + + AD++L E L Y Sbjct: 126 RSGGGTSPEGQAAIAIAAERLR-RPLARLERHFAA--EDYLVGGRFTVADLNLAETLRY- 181 Query: 168 EELDSSLISSFPLLKALKTRISNLPTVKKFLQ 199 + +L+ FP + A R + P + ++ Sbjct: 182 GQAHPALLEPFPAVAAWLDRCQSRPAFRLMME 213 >1AXD-A nrPDB Length = 209 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 9/154 (5%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYN---LYGKDIKEKALIDMYIEGIADLGEMILL 108 F QVP ++ + L ++RAI Y A K L +++E A++D++IE A+ L Sbjct: 51 FGQVPALQDGDLYLFESRAICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALN 110 Query: 109 LPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSH-----GQDYLVGNKLSRADI-HLVE 162 Q +K + +KVL+ + YL G+ LS AD+ H+ Sbjct: 111 PILFQVLISPMLGGTTDQKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSV 170 Query: 163 LLYYVEELDSSLISSFPLLKALKTRISNLPTVKK 196 L +S++ ++P +KA + + P+V+K Sbjct: 171 TLCLFATPYASVLDAYPHVKAWWSGLMERPSVQK 204 >3IBH-A nrPDB Length = 233 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 23/162 (14%) Query: 55 VPMVEID-GMKLVQTRAILNYIAS---KYNLYGKDIKEKALIDMYIEGIADLGEMILLLP 110 VP++E+D G + + AI YI + L GK EK +I M + E+ LL P Sbjct: 72 VPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHM----MNKRAELELLDP 127 Query: 111 FS----------QPEE---QDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRAD 157 S PE Q+ + L Q F+ VL+ + Y+ G+ S AD Sbjct: 128 VSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRE--RPYVAGDSFSMAD 185 Query: 158 IHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQ 199 I ++ L + + + L+A R+ P+VKK L+ Sbjct: 186 ITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLE 227 >1PN9-A nrPDB Length = 209 Score = 35.8 bits (81), Expect = 0.016, Method: Compositional matrix adjust. Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 30/154 (19%) Query: 55 VPMVEIDGMKLVQTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLP 110 +P + +G L ++RAI Y+A KY LY KD +++A+++ + D+G + Sbjct: 52 IPTLVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRL--YFDMGTLY---- 105 Query: 111 FSQPEEQDAKLALIQEKTKNRYFPAFEKVLKS---------HGQDYLVGNKLSRADIHLV 161 ++ A Q K P EK +K GQ+Y GN L+ AD+ L Sbjct: 106 -----QRFADYHYPQIFAKQPANPENEKKMKDAVGFLNTFLEGQEYAAGNDLTIADLSLA 160 Query: 162 ELL--YYVEELDSSLISSFPLLKALKTRI-SNLP 192 + Y V D + +P + A R +N P Sbjct: 161 ATIATYEVAGFD---FAPYPNVAAWFARCKANAP 191 >3GH6-A nrPDB Length = 210 Score = 35.4 bits (80), Expect = 0.020, Method: Compositional matrix adjust. Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 8/94 (8%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPMVEIDGM 63 L+Y S+ A GVEF++K I + ++ + YL +P + G Sbjct: 3 LYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPE-YLKINPQHTIPTLHDHGF 61 Query: 64 KLVQTRAILNYIASKYN----LYGKDIKEKALID 93 L ++RAI+ Y+ KY L+ KD++++ALI+ Sbjct: 62 ALWESRAIMVYLVEKYGKDDKLFPKDVQKQALIN 95 >2GDR-A nrPDB Length = 202 Score = 34.7 bits (78), Expect = 0.031, Method: Compositional matrix adjust. Identities = 44/182 (24%), Positives = 79/182 (43%), Gaps = 25/182 (13%) Query: 28 VEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID-GMKLVQTRAILNYIASKYNLYGKDI 86 V+ K S +D ++ GY VP +++D G L + AI+ Y+A + + GK + Sbjct: 30 VDLASKKTASGQDYLEVNPAGY-----VPCLQLDDGRTLTEGPAIVQYVADQ--VPGKQL 82 Query: 87 KEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSH-GQ 145 G + + L F E + L + + + A + L + GQ Sbjct: 83 APA-------NGSFERYHLQQWLNFISSELHKSFSPLFNPASSDEWKNAVRQSLNTRLGQ 135 Query: 146 --------DYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKF 197 YL+G++LS ADI+L +L + ++ L S +P L+A + R+ V+ Sbjct: 136 VARQLEHAPYLLGDQLSVADIYLFVVLGWSAYVNIDL-SPWPSLQAFQGRVGGREAVQSA 194 Query: 198 LQ 199 L+ Sbjct: 195 LR 196 >3MAK-A nrPDB Length = 209 Score = 34.7 bits (78), Expect = 0.033, Method: Compositional matrix adjust. Identities = 42/181 (23%), Positives = 71/181 (39%), Gaps = 58/181 (32%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY----NLYGKDIKEKALIDMYIEGIADLGEMILL 108 +P + +G L ++RAI Y+ KY +LY K K++A+I+ + D+G + Sbjct: 51 HTIPTLVDNGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRL--YFDMGTLY-- 106 Query: 109 LPFSQPEEQDAKLALIQEKTKNRYFP-----------AFEKVLKS--------HGQDYLV 149 + N Y+P AF+K+ + GQDY Sbjct: 107 -----------------QSFANYYYPQVFAKAPADPEAFKKIEAAFEFLNTFLEGQDYAA 149 Query: 150 GNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMD 209 G+ L+ ADI LV + +S+F + K IS V ++ + P + Sbjct: 150 GDSLTVADIALV-----------ATVSTF---EVAKFEISKYANVNRWYENAKKVTPGWE 195 Query: 210 E 210 E Sbjct: 196 E 196 >1AW9-A nrPDB Length = 216 Score = 34.3 bits (77), Expect = 0.039, Method: Compositional matrix adjust. Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 17/169 (10%) Query: 52 FQQVPMVEIDGMK-LVQTRAILNYIASKYNLYGKDI----KEKALIDMYIEG-----IAD 101 F Q+P + +DG + L ++RAI YIASKY G D+ A +++++E + Sbjct: 51 FGQIPAL-VDGDEVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPN 109 Query: 102 LGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADI- 158 ++ L +P A A + +K + + V ++H YL G++ + AD Sbjct: 110 ASPLVFQL-LVRPLLGGAPDAAVVDKHAEQLAKVLD-VYEAHLARNKYLAGDEFTLADAN 167 Query: 159 HLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 H LLY + + L+++ P +KA I P +K + P PP Sbjct: 168 HASYLLYLSKTPKAGLVAARPHVKAWWEAIVARPAFQKTVA-AIPLPPP 215 >3UBL-A nrPDB Length = 242 Score = 34.3 bits (77), Expect = 0.047, Method: Compositional matrix adjust. Identities = 35/157 (22%), Positives = 77/157 (49%), Gaps = 9/157 (5%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KLH ++I + ++ + G+E+E+ I +++ D L+ ++P++E+DG + Sbjct: 5 KLHGASISNYVNKVKLGILEKGLEYEQIRIAPSQEEDFLKISP---MGKIPVLEMDGKFI 61 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA--L 123 ++ AIL ++ + + K I E + I+ + E L +P + AK++ + Sbjct: 62 FESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPEI 121 Query: 124 IQE--KTKNRYFPAFEKVLKSHGQDYLVGNKLSRADI 158 ++E T + A ++V++ Y+ GN + AD Sbjct: 122 VEEVHSTLVKGIKALQRVVRF--SPYIAGNVFTLADC 156 >5A5K-A nrPDB Length = 212 Score = 33.1 bits (74), Expect = 0.087, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDI 86 F QVP E +KL ++RAI YIA +Y G ++ Sbjct: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 >5LOL-A nrPDB Length = 215 Score = 33.1 bits (74), Expect = 0.098, Method: Compositional matrix adjust. Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 11/115 (9%) Query: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQ 113 +VP+V++DG + + I+ + KY + K + G G + L S+ Sbjct: 61 KVPVVKLDGKWVADSDVIVGLLEEKY----PEPSLKTPPEFASVGSKIFGAFVTFLK-SK 115 Query: 114 PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 ++ AL+ E A E LK+H ++ G K++ D+ L LY++E Sbjct: 116 DANDGSEKALVDE------LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 164 >1JLV-A nrPDB Length = 209 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 24/173 (13%) Query: 55 VPMVEIDGMKLVQTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMIL-LL 109 +P + +G L ++RAI Y+A KY LY KD +++A+++ + D+G + Sbjct: 52 IPTLVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRL--YFDMGTLYQRFA 109 Query: 110 PFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEE 169 + P+ + A + + K + F G Y+ G+ L+ AD+ +L V Sbjct: 110 DYYYPQIFAKQPANAENEKKMKDAVDFLNTFLD-GHKYVAGDSLTIADL---TVLATVST 165 Query: 170 LDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKP--PMDEKSLEESRKIF 220 D ++ F L K P V + + P ++E +EE RK F Sbjct: 166 YD---VAGFELAK--------YPHVAAWYERTRKEAPGAAINEAGIEEFRKYF 207 >6F05-A nrPDB Length = 215 Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 33/52 (63%), Gaps = 7/52 (13%) Query: 52 FQQVPMVEIDG-MKLVQTRAILNYIASKY-----NLYGKDIKEKALIDMYIE 97 F VP V +DG K+ ++RA++ Y+A KY +L GK ++++ ++ +++ Sbjct: 50 FGTVPAV-VDGDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLD 100 >4FQU-A nrPDB Length = 313 Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 10/84 (11%) Query: 119 AKLALIQEKTKNRYFPAFEKV--LKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 + A QE + ++P F+ + L+ H G+++LVG++L+ ADI L L D+ Sbjct: 186 SGFATTQEAYEEAFYPLFDTLDWLEEHLTGREWLVGDRLTEADIRLFPTLV---RFDAIY 242 Query: 175 ISSFPLLKALKTRISNLPTVKKFL 198 F K RI++ P + + + Sbjct: 243 HGHF---KCNLRRIADYPNLSRLV 263 >3PPU-A nrPDB Length = 352 Score = 31.2 bits (69), Expect = 0.36, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 6/68 (8%) Query: 137 EKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL-LKALKTRISNLPTVK 195 EK+L+ GQDYL+G +L+ ADI L + D ++ F L+ ++ NL Sbjct: 249 EKMLE--GQDYLIGGQLTEADI---RLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWM 303 Query: 196 KFLQPGSP 203 + L G+P Sbjct: 304 RKLYWGNP 311 >3LG6-A nrPDB Length = 235 Score = 30.8 bits (68), Expect = 0.47, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 29/50 (58%), Gaps = 1/50 (2%) Query: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182 F A EK+L+ + VG++++ AD+ LV ++ E + L + FP+ K Sbjct: 158 FGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAAERVGMDL-ARFPITK 206 >5F0G-A nrPDB Length = 215 Score = 30.8 bits (68), Expect = 0.53, Method: Compositional matrix adjust. Identities = 41/184 (22%), Positives = 84/184 (45%), Gaps = 21/184 (11%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQ--VPMVEIDGMK 64 +Y G ++ + A G+E +K + + E ++L+ + + Q +P + +G Sbjct: 3 FYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEG-EQLKPEFVKLNPQHTIPTLVDNGFS 61 Query: 65 LVQTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMI-----LLLPFSQPE 115 + ++RAI Y+ KY L D K++A+I+ + D+G + P + Sbjct: 62 IWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRL--YFDMGTLYESFAKYYYPLFRTG 119 Query: 116 EQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELL--YYVEELDSS 173 + + L + +T + F GQ+Y+ G++L+ ADI ++ + + V E D S Sbjct: 120 KPGSDEDLKRIETAFGFLDTF-----LEGQEYVAGDQLTVADIAILSTVSTFEVSEFDFS 174 Query: 174 LISS 177 S+ Sbjct: 175 KYSN 178 >5V8F-F nrPDB Length = 435 Score = 30.4 bits (67), Expect = 0.64, Method: Compositional matrix adjust. Identities = 24/112 (21%), Positives = 48/112 (42%), Gaps = 10/112 (8%) Query: 102 LGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVL--------KSHGQDYLVGNKL 153 + E++ L P +P+ L + T Y + KV+ + H Y+ K+ Sbjct: 10 VAEVLRLDPQEKPDWSSGYLKKLTNATSILYNTSLNKVMLKQDEEVARCHICAYIASQKM 69 Query: 154 SRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRK 205 + H+ +L YY++ + + L+ + +SN +K+F SP+K Sbjct: 70 NEK--HMPDLCYYIDSIPLEPKKAKHLMNLFRQSLSNSSPMKQFAWTPSPKK 119 >5F05-A nrPDB Length = 212 Score = 30.4 bits (67), Expect = 0.67, Method: Compositional matrix adjust. Identities = 42/162 (25%), Positives = 63/162 (38%), Gaps = 20/162 (12%) Query: 52 FQQVPMVEIDG-MKLVQTRAILNYIASKYNLYGKDIKEK----ALIDMYIEGIAD----- 101 F QVP +DG +KL ++RAI Y+A +Y G + A I ++ E + Sbjct: 51 FGQVPAA-VDGDLKLFESRAISQYVAHQYASKGTQLGAAGNGYATILVWQEVESHQFDPS 109 Query: 102 ----LGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRAD 157 + E + F P DA L E T + +E L YL + + AD Sbjct: 110 ASKLVWEQVFKPVFGLP--TDAALVAETEVTLGKVLDVYEARLSQ--SKYLASDSFTLAD 165 Query: 158 I-HLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFL 198 + HL + + L S P + A I+ P K L Sbjct: 166 LHHLPNIQALLGTPSKKLFDSRPHVSAWVASITGRPAWGKVL 207 >6GCB-A nrPDB Length = 325 Score = 30.0 bits (66), Expect = 0.89, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 13/87 (14%) Query: 119 AKLALIQEKTKNRYFPAFE------KVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS 172 A A Q+ + P FE K+L G+DYLVG++L+ AD V L + D Sbjct: 195 AGFATTQQAYEAAVIPLFESLDRLEKILT--GKDYLVGDQLTEAD---VRLFVTIIRFDP 249 Query: 173 SLISSFPLLKALKTRISNLPTVKKFLQ 199 + + F L+T P + +L+ Sbjct: 250 AYVGHFKC--NLRTIRDGYPAIHLWLR 274 >6GC9-A nrPDB Length = 327 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 14/24 (58%), Positives = 19/24 (79%), Gaps = 2/24 (8%) Query: 137 EKVLKSHGQDYLVGNKLSRADIHL 160 EK+L G+DYLVG++L+ ADI L Sbjct: 220 EKILT--GKDYLVGDQLTEADIRL 241 >1BB9-A nrPDB Length = 115 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 103 GEMILLLPFSQPEEQD-AKLALIQEKTKNRY 132 G+++L++PF PEEQD L ++E N++ Sbjct: 66 GDVVLVIPFQNPEEQDEGWLMGVKESDWNQH 96 >1MV0-B nrPDB Length = 81 Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 103 GEMILLLPFSQPEEQD-AKLALIQEKTKNRY 132 G+++L++PF PEEQD L ++E N++ Sbjct: 32 GDVVLVIPFQNPEEQDEGWLMGVKESDWNQH 62 >5ELG-A nrPDB Length = 221 Score = 28.1 bits (61), Expect = 3.1, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 A E LKSH ++ G ++S D+ L LY+++ Sbjct: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 >5WTZ-A nrPDB Length = 421 Score = 28.1 bits (61), Expect = 3.3, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 40 DLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGI 99 D K +N L ++ V ++ + ++ +I NYI + + IK+K +D Y EGI Sbjct: 11 DFAKDKNSATLWAKKRKQVWLNNLSKAESTSINNYIKNSSEINSYSIKKKFALDNY-EGI 69 Query: 100 ADLGE 104 L E Sbjct: 70 ETLNE 74 >1MV3-A nrPDB Length = 213 Score = 28.1 bits (61), Expect = 3.4, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 103 GEMILLLPFSQPEEQD-AKLALIQEKTKNRY 132 G+++L++PF PEEQD L ++E N++ Sbjct: 164 GDVVLVIPFQNPEEQDEGWLMGVKESDWNQH 194 >3FD5-A nrPDB Length = 394 Score = 27.7 bits (60), Expect = 3.8, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 5/90 (5%) Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQ---PEEQD 118 G+ LVQT + I + G+ L D+Y G+ + M++LL S E+D Sbjct: 81 GLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERD 140 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYL 148 + LI + K+ A V + GQ L Sbjct: 141 KVMPLIIQGFKDAAEEAGTSV--TGGQTVL 168 >3BBY-A nrPDB Length = 215 Score = 27.7 bits (60), Expect = 3.8, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 9/72 (12%) Query: 27 GVEFEEKFIK--SAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKY----- 79 G+ F K I S E L GY ++VP+++ID +L ++ AI Y+ ++ Sbjct: 31 GLSFHIKTIDLDSGEHLQPTWQ-GYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTW 89 Query: 80 -NLYGKDIKEKA 90 +Y D++ +A Sbjct: 90 ERIYPLDLENRA 101 >2IL3-A nrPDB Length = 221 Score = 27.7 bits (60), Expect = 4.4, Method: Compositional matrix adjust. Identities = 37/176 (21%), Positives = 82/176 (46%), Gaps = 28/176 (15%) Query: 25 AAGVEFEEKFIKSAEDLDKLRNDGYLMFQQ--VPMVEIDGMKLVQTRAILNYIASKY--- 79 A G+E E+K I D L+ + + Q +P+++ +G + ++ AI+ Y+ +KY Sbjct: 24 ALGLELEQKTINLLTG-DHLKPEFVKLNPQHTIPVLDDNGTIITESHAIMIYLVTKYGKD 82 Query: 80 -NLYGKDIKEKALID--MYIEGIADLGEMIL----LLPFSQPEEQDAKLALIQEKTKNRY 132 +LY KD ++A ++ ++ E M +L F + + + ++ +Q+ Sbjct: 83 DSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFGKSDIPEDRVEYVQK------ 136 Query: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRI 188 ++E + + D++ G ++ AD + + SS++ PL ++ RI Sbjct: 137 --SYELLEDTLVDDFVAGPTMTIADFSCISTI-------SSIMGVVPLEQSKHPRI 183 >3FDD-A nrPDB Length = 533 Score = 27.3 bits (59), Expect = 5.0, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 2/30 (6%) Query: 192 PTVKKF--LQPGSPRKPPMDEKSLEESRKI 219 P +K F + P +P MDE+SLE RKI Sbjct: 244 PAIKIFFCVNPSNPPSVKMDERSLERVRKI 273 >2C3Q-A nrPDB Length = 247 Score = 27.3 bits (59), Expect = 5.6, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 28/49 (57%), Gaps = 4/49 (8%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDIKEKALIDMYI 96 ++VP ++ L ++ AIL Y+ KY + Y +D++ +A +D Y+ Sbjct: 58 LKKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYL 106 >5D9W-A nrPDB Length = 230 Score = 26.9 bits (58), Expect = 6.8, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Query: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE 168 A E+ LK+HG ++ G +S AD+ L LY+++ Sbjct: 147 ALEEHLKAHGP-FINGQNISAADLSLAPKLYHLQ 179 >5DXT-A nrPDB Length = 962 Score = 26.9 bits (58), Expect = 7.4, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 26/41 (63%), Gaps = 1/41 (2%) Query: 147 YLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTR 187 YL +KLS+ I LV++L Y + LD+ L+ F L KAL + Sbjct: 516 YLTDDKLSQYLIQLVQVLKYEQYLDNLLV-RFLLKKALTNQ 555 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2VCT-A nrPDB 304 2e-83 2VCV-A nrPDB 302 7e-83 3I6A-A nrPDB 302 8e-83 1PL2-A nrPDB 299 6e-82 5LCZ-A nrPDB 288 1e-78 1F3B-A nrPDB 288 1e-78 1EV4-A nrPDB 273 4e-74 1B48-A nrPDB 272 7e-74 1VF1-A nrPDB 271 1e-73 1GUL-A nrPDB 252 9e-68 3GTU-B nrPDB 235 1e-62 1XWK-A nrPDB 225 1e-59 5FWG-A nrPDB 225 1e-59 4GTU-A nrPDB 225 1e-59 1B4P-A nrPDB 222 8e-59 2DC5-A nrPDB 220 3e-58 2FHE-A nrPDB 218 2e-57 5D73-A nrPDB 217 4e-57 5AN1-A nrPDB 216 7e-57 1HNA-A nrPDB 215 2e-56 2GSR-A nrPDB 209 7e-55 1GSU-A nrPDB 208 2e-54 1TU7-A nrPDB 203 6e-53 2GLR-A nrPDB 201 2e-52 4Q5F-A nrPDB 200 3e-52 4Q5R-A nrPDB 200 4e-52 1FHE-A nrPDB 199 1e-51 1B8X-A nrPDB 198 2e-51 18GS-A nrPDB 198 2e-51 3KXO-A nrPDB 197 3e-51 2WRT-A nrPDB 197 5e-51 1DUG-A nrPDB 195 1e-50 1BG5-A nrPDB 195 1e-50 1GSQ-A nrPDB 191 2e-49 5Y9Z-A nrPDB 189 8e-49 4Q5Q-A nrPDB 189 1e-48 2AAW-A nrPDB 187 4e-48 4WR5-A nrPDB 186 7e-48 1ZL9-A nrPDB 185 2e-47 1M0U-A nrPDB 184 3e-47 1YQ1-A nrPDB 179 1e-45 2CA8-A nrPDB 170 5e-43 1U3I-A nrPDB 167 3e-42 2WDU-A nrPDB 164 3e-41 2HNL-A nrPDB 161 3e-40 2CZ2-A nrPDB 153 4e-38 1FW1-A nrPDB 153 4e-38 3LSZ-A nrPDB 126 5e-30 5F07-A nrPDB 126 8e-30 4PNG-A nrPDB 123 4e-29 5EY6-A nrPDB 121 3e-28 4YH2-A nrPDB 111 2e-25 4RI7-A nrPDB 108 2e-24 5F06-A nrPDB 108 3e-24 1F2E-A nrPDB 100 5e-22 Sequences not found previously or not previously below threshold: 1AXD-A nrPDB 101 2e-22 6F05-A nrPDB 97 5e-21 3VWX-A nrPDB 96 1e-20 1AW9-A nrPDB 91 4e-19 1E6B-A nrPDB 88 3e-18 5F05-A nrPDB 84 4e-17 1PN9-A nrPDB 84 4e-17 1JLV-A nrPDB 84 4e-17 2IL3-A nrPDB 84 5e-17 5A5K-A nrPDB 83 6e-17 3UAR-A nrPDB 81 3e-16 4IGJ-A nrPDB 81 4e-16 5ZWP-A nrPDB 80 9e-16 2GDR-A nrPDB 80 1e-15 3M3M-A nrPDB 78 4e-15 5F0G-A nrPDB 76 8e-15 3MAK-A nrPDB 76 8e-15 4MPF-A nrPDB 76 8e-15 1V2A-A nrPDB 75 2e-14 3M8N-A nrPDB 74 6e-14 2C3Q-A nrPDB 73 1e-13 4PXO-A nrPDB 72 1e-13 3PR8-A nrPDB 71 3e-13 3GH6-A nrPDB 71 4e-13 3IBH-A nrPDB 70 9e-13 3UBL-A nrPDB 67 5e-12 3LFL-A nrPDB 66 8e-12 2PMT-A nrPDB 65 2e-11 3TOT-A nrPDB 65 2e-11 2PVQ-A nrPDB 64 4e-11 5ELG-A nrPDB 64 4e-11 4J2F-A nrPDB 63 7e-11 5LOL-A nrPDB 63 8e-11 3LG6-A nrPDB 63 1e-10 3NIV-A nrPDB 63 1e-10 4QQ7-A nrPDB 62 2e-10 2JL4-A nrPDB 60 1e-09 4CHS-A nrPDB 59 1e-09 4MK3-A nrPDB 58 2e-09 3GX0-A nrPDB 58 3e-09 4IKH-A nrPDB 58 4e-09 4MDC-A nrPDB 58 4e-09 2VO4-A nrPDB 58 5e-09 5J5N-A nrPDB 57 5e-09 3C8E-A nrPDB 57 6e-09 5F8B-A nrPDB 56 2e-08 5N9U-A nrPDB 56 2e-08 5NR1-A nrPDB 55 3e-08 5G5A-A nrPDB 55 4e-08 5ECL-B nrPDB 53 9e-08 3RBT-A nrPDB 51 3e-07 1N2A-A nrPDB 49 1e-06 4BVY-B nrPDB 49 2e-06 3PPU-A nrPDB 49 2e-06 4PQI-A nrPDB 48 3e-06 4FQU-A nrPDB 46 1e-05 4AGS-A nrPDB 46 1e-05 6JWK-A nrPDB 46 1e-05 6GC9-A nrPDB 46 2e-05 1G6W-A nrPDB 46 2e-05 5IQY-A nrPDB 45 3e-05 6GCB-A nrPDB 44 4e-05 3BBY-A nrPDB 42 2e-04 1GWC-A nrPDB 41 4e-04 4G0L-A nrPDB 41 4e-04 6GZF-A nrPDB 38 0.004 3FY7-A nrPDB 37 0.006 4USS-A nrPDB 37 0.008 4PTS-A nrPDB 37 0.008 3M1G-A nrPDB 34 0.055 4XRU-B nrPDB 33 0.12 2YV7-A nrPDB 31 0.32 2JZR-A nrPDB 31 0.34 4K0G-A nrPDB 31 0.44 3IR4-A nrPDB 31 0.54 5Y7I-A nrPDB 30 0.66 5LKB-A nrPDB 30 0.73 1OYJ-A nrPDB 30 0.95 4LMW-A nrPDB 29 1.4 4CZI-A nrPDB 28 2.4 2H30-A nrPDB 28 2.8 2JB2-A nrPDB 28 4.2 6EN4-C nrPDB 28 5.0 5VAT-A nrPDB 28 5.1 3QAO-A nrPDB 27 5.6 5E1J-A nrPDB 27 8.0 5T2A-v nrPDB 26 9.0 >2VCT-A nrPDB Length = 222 Score = 304 bits (778), Expect = 2e-83, Method: Composition-based stats. Identities = 221/222 (99%), Positives = 222/222 (100%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPF+QPEEQDAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 >2VCV-A nrPDB Length = 222 Score = 302 bits (774), Expect = 7e-83, Method: Composition-based stats. Identities = 197/222 (88%), Positives = 208/222 (93%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA KPKLHY N RGRME IRWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMY EG+ADL EMILLLP +PEE+DAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 +ALI+EKTK+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEE+RKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 >3I6A-A nrPDB Length = 222 Score = 302 bits (774), Expect = 8e-83, Method: Composition-based stats. Identities = 201/221 (90%), Positives = 207/221 (93%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMYIEGIADLGEMI++LPF PEE+DAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 LALI+EK KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 LKALKTRISNLPTVKKFLQPGSPRKPP DE + IFR Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPPDEIYVRTVYNIFR 221 >1PL2-A nrPDB Length = 222 Score = 299 bits (766), Expect = 6e-82, Method: Composition-based stats. Identities = 210/222 (94%), Positives = 214/222 (96%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQ RAILNYIASKYNLYGKDIKE+ALIDMYIEGIADLGEMILLLP PEE+DAK Sbjct: 61 DGMKLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 LALI+EK KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEE+RKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222 >5LCZ-A nrPDB Length = 222 Score = 288 bits (738), Expect = 1e-78, Method: Composition-based stats. Identities = 179/222 (80%), Positives = 199/222 (89%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MAEKPKLHY N RGRMES RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIASKYNLYGKD+KE+ALIDMY EGI DL EMI+ L P++++AK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAK 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 AL +++TKNRY PAFEKVLKSHGQDYLVGN+L+R DIHL+ELL YVEE D+SL++SFPL Sbjct: 121 TALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLLTSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 LKA K+RIS+LP VKKFLQPGS RKP MD K +EE+RKIFRF Sbjct: 181 LKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARKIFRF 222 >1F3B-A nrPDB Length = 222 Score = 288 bits (737), Expect = 1e-78, Method: Composition-based stats. Identities = 161/220 (73%), Positives = 188/220 (85%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 A KP LHY N RGRME IRWLLAAAGVEFEEKFI+S EDL+KL+ DG LMF QVPMVEID Sbjct: 1 AGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 GMKL QTRAILNYIA+KY+LYGKD+KE+ALIDMY EGI DL EMI L P++++AK Sbjct: 61 GMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKT 120 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 AL +++TKNRY PAFEKVLKSHGQDYLVGN+L+R DIHL+E+L YVEE D+SL++ FPLL Sbjct: 121 ALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 KA K+RIS+LP VKKFLQPGS RKPPMD K ++E+RK F+ Sbjct: 181 KAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFK 220 >1EV4-A nrPDB Length = 221 Score = 273 bits (699), Expect = 4e-74, Method: Composition-based stats. Identities = 162/221 (73%), Positives = 191/221 (86%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 + KP LHY N RGRME IR+LLAAAGVEF+EKFI+S EDL+KL+ DG LMF QVPMVEID Sbjct: 1 SGKPVLHYFNARGRMECIRFLLAAAGVEFDEKFIQSPEDLEKLKKDGNLMFDQVPMVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 GMKL QTRAILNYIA+KY+LYGKD+KE+ALIDMY EGI DL EMI+ L P++++AK Sbjct: 61 GMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQKEAKT 120 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 AL +++TKNRY PAFEKVLKSHGQDYLVGNKL+R DIHL+ELL YVEE D+SL++SFPLL Sbjct: 121 ALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFDASLLTSFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 KA K+RIS+LP VKKFLQPGS RK PMD K +EE+RKI++F Sbjct: 181 KAFKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARKIYKF 221 >1B48-A nrPDB Length = 221 Score = 272 bits (697), Expect = 7e-74, Method: Composition-based stats. Identities = 134/221 (60%), Positives = 171/221 (77%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 A KPKL+Y N RGRMESIRWLLAAAGVEFEE+F+++ E +K++ DG+L+F QVP+VEID Sbjct: 1 AAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 GM L QTRAIL+Y+A+KYNLYGKD+KE+ IDMY +G DL MI + PF P+E++ Sbjct: 61 GMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESY 120 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 LI + K RYFP FEK+LK HG+ +LVGN+LS ADI L+E + VEEL + ++S FPLL Sbjct: 121 DLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 +A KTRISN+PT+KKFLQPGS RKPP D +E R + +F Sbjct: 181 QAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRIVLKF 221 >1VF1-A nrPDB Length = 229 Score = 271 bits (694), Expect = 1e-73, Method: Composition-based stats. Identities = 141/221 (63%), Positives = 170/221 (76%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA KP L+Y N RG+MESIRWLLAAAGVEFEE F+++ E +KL G LMFQQVPMVEI Sbjct: 1 MAAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTRAILNYIA KYNLYGKD+KE+ALIDMY+ G DL +L PF E++ + Sbjct: 61 DGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQ 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 A + EK +RYFPA+EKVLK HGQD+LVGN+LS ADIHL+E + VEE S +S FPL Sbjct: 121 CAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKSDALSGFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 L+A K RIS++PT+KKFL PGS RKP D+K +E R++ R Sbjct: 181 LQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRRVLR 221 >1GUL-A nrPDB Length = 222 Score = 252 bits (644), Expect = 9e-68, Method: Composition-based stats. Identities = 120/221 (54%), Positives = 173/221 (78%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA +PKLHY N RGRMES+RW+LAAAGVEF+E+F+++ E L KL++ +L+FQQVPMVEI Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 DGMKLVQTR+IL+YIA K+NL+GK++KE+ LIDMY+EG DL E++++ PF +P++Q + Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + + +K RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ + +EE +++S+FP Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFR 221 L+ ++SN+PT+K+FL+PGS +KPP DE + IFR Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221 >3GTU-B nrPDB Length = 224 Score = 235 bits (599), Expect = 1e-62, Method: Composition-based stats. Identities = 60/225 (26%), Positives = 91/225 (40%), Gaps = 22/225 (9%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFI--KSAEDLDK-----LRNDGYLMFQQVPMV 58 L Y +IRG +IR LL +EEK A D D+ ++ L F +P + Sbjct: 7 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 66 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 K+ Q+ AIL YIA K+N+ G+ +EK +D+ + D ++ L +S Sbjct: 67 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSD---- 122 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSS 173 EK K +Y LK + G KL+ D ++L D Sbjct: 123 ------HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 176 Query: 174 LISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 + FP LKA R L + +LQ K P++ K + K Sbjct: 177 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >1XWK-A nrPDB Length = 218 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 12/220 (5%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVPMV 58 L Y +IRG +IR LL +EEK + A D D+ N+ + L F +P + Sbjct: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 K+ Q+ AIL YIA K+NL G+ +EK +D+ D + ++ + PE + Sbjct: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICY-NPEFEK 122 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 K ++E + + L + + GNK++ D + ++L + + +F Sbjct: 123 LKPKYLEEL--PEKLKLYSEFLGK--RPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAF 178 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 P LK +R L + +++ P+ K K Sbjct: 179 PNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >5FWG-A nrPDB Length = 217 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 51/220 (23%), Positives = 94/220 (42%), Gaps = 12/220 (5%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVPMV 58 L Y N+RG IR LL +EEK + A D D+ N+ + L F +P + Sbjct: 3 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 62 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 K+ Q+ AI+ Y+A K++L G+ +E+ D+ + D +++L ++ E+ Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 122 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L KT + + L + + G+K++ D ++L + + +F Sbjct: 123 KPEFL---KTIPEKMKLYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAF 177 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 P LK R L + +++ P+ K + S K Sbjct: 178 PNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >4GTU-A nrPDB Length = 217 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 54/219 (24%), Positives = 97/219 (44%), Gaps = 12/219 (5%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVPMVE 59 L Y +IRG +IR LL +EEK + A D D+ N+ + L F +P + Sbjct: 4 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 63 Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119 K+ Q+ AIL YIA K+NL G+ +EK +D+ D+ + + +S P+ + Sbjct: 64 DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYS-PDFEKL 122 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179 K ++E F + L + + VG+K++ D ++L + + + +FP Sbjct: 123 KPEYLEEL--PTMMQHFSQFLGK--RPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFP 178 Query: 180 LLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 LK +R L + +++ P+ + K Sbjct: 179 NLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >1B4P-A nrPDB Length = 217 Score = 222 bits (567), Expect = 8e-59, Method: Composition-based stats. Identities = 51/220 (23%), Positives = 93/220 (42%), Gaps = 12/220 (5%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVPMV 58 L Y N+RG IR LL +EEK + A D D+ N+ + L F +P + Sbjct: 3 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 62 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 K+ Q+ AI+ Y+A K++L G+ +E+ +D+ D + ++ +S E+ Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFERK 122 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L + + + L Q + GNK++ D + ++L + + +F Sbjct: 123 KPEYL---EGLPEKMKLYSEFLGK--QPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAF 177 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 P LK R L + +++ G P+ K + K Sbjct: 178 PNLKDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >2DC5-A nrPDB Length = 231 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 49/224 (21%), Positives = 92/224 (41%), Gaps = 22/224 (9%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVPMVE 59 L Y +IRG +IR L +EEK + A D D+ N+ + L F +P + Sbjct: 12 LGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLI 71 Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119 K+ Q+ AIL Y+ K+NL G+ +E+ +D+ + D ++ L ++ Sbjct: 72 DGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADF---- 127 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELDSSL 174 EK K Y +++ + + + G+K++ D ++L + ++ Sbjct: 128 ------EKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKC 181 Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 + +FP LK R L + +++ PM K Sbjct: 182 LDAFPNLKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGSN 225 >2FHE-A nrPDB Length = 216 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 58/216 (26%), Positives = 98/216 (45%), Gaps = 13/216 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEIDG 62 KL Y IRG + +R LL G ++EE+ I +D +K + + L +P D Sbjct: 3 KLGYWKIRGLQQPVRLLLEYLGEKYEEQ-IYERDDGEKWFSKKFELGLDLPNLPYYIDDK 61 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 KL Q+ AIL YIA K+ + G +E+A + M DL + I + + QP+ + K Sbjct: 62 CKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISY-QPKFEQLKEG 120 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQ--DYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 +++ P K+ YL G +S D + E L + L+ + FP Sbjct: 121 YLKD------LPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPN 174 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEES 216 L+ +RI LP++K +++ K P++ + Sbjct: 175 LQQFMSRIEALPSIKAYMESNRFIKWPLNGWHAQFG 210 >5D73-A nrPDB Length = 208 Score = 217 bits (552), Expect = 4e-57, Method: Composition-based stats. Identities = 61/209 (29%), Positives = 104/209 (49%), Gaps = 8/209 (3%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGM 63 KL Y IRG E IR +L G++F + I A D +++ + F Q+P + Sbjct: 2 SYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRIN-ASDWPSMKS--HFHFGQLPCLYDGDH 58 Query: 64 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLAL 123 ++VQ+ AIL ++A K+NL G + E IDM+ EG+ DL + + + + Sbjct: 59 QIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYDTEKDSYI- 117 Query: 124 IQEKTKNRYFPAFEKVL--KSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 + FEK+L + G+++++G K+S D L E L + LD + FPLL Sbjct: 118 --KDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCLDKFPLL 175 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPMDE 210 KA R+ + P +K++ + + K P++ Sbjct: 176 KAYHQRMEDRPGLKEYCKQRNRAKIPVNG 204 >5AN1-A nrPDB Length = 219 Score = 216 bits (550), Expect = 7e-57, Method: Composition-based stats. Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 14/217 (6%) Query: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDK-----LRNDGYLMFQQVPM 57 P L Y R + IR +L G EFEEK + A D DK ++ L F +P Sbjct: 3 PVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPY 62 Query: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQ 117 +K+ Q++AI+ Y+A K+ L G +E DM + D+ E + + E++ Sbjct: 63 YIDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHYEQK 122 Query: 118 DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 DA A + K + + L S + + G+KL+ D E+ LD + + Sbjct: 123 DAYTASLPAKLR-----QYSDFLGS--RPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDG 175 Query: 178 FPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLE 214 F L+A + R +L +KK++ K P+ K + Sbjct: 176 FKNLQAFQKRFEDLEAIKKYMASPKFLKKPICNKYAQ 212 >1HNA-A nrPDB Length = 217 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 60/224 (26%), Positives = 95/224 (42%), Gaps = 22/224 (9%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVPMVE 59 L Y NIRG SIR LL +EEK + A D D+ N+ + L F +P + Sbjct: 4 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 63 Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119 K+ Q+ AIL YIA K+NL G+ KE+ D+ D + L + Sbjct: 64 DGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF---- 119 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHG-----QDYLVGNKLSRADIHLVELLYYVEELDSSL 174 EK K Y A ++LK + Q + +G+K++ D ++L + + S Sbjct: 120 ------EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSC 173 Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 + +FP LK +R L + +++ P+ K K Sbjct: 174 LDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >2GSR-A nrPDB Length = 207 Score = 209 bits (533), Expect = 7e-55, Method: Composition-based stats. Identities = 65/210 (30%), Positives = 107/210 (50%), Gaps = 9/210 (4%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 + Y +RGR E++R LLA ++E+ + E L+ +F+Q+P + Sbjct: 1 PPYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTM-ETWPPLKPS--CLFRQLPKFQDGD 57 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 + L Q+ AIL ++ + LYGKD KE AL+DM +G+ DL L ++ E K Sbjct: 58 LTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYTNYEAGKEKYV 117 Query: 123 LIQEKTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 K + FE +L + GQ ++VG+++S AD +L++LL + L+ S + +FPL Sbjct: 118 ----KELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDAFPL 173 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDE 210 L A R+S P +K FL P++ Sbjct: 174 LSAYVARLSARPKIKAFLASPEHVNRPING 203 >1GSU-A nrPDB Length = 219 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 53/219 (24%), Positives = 85/219 (38%), Gaps = 12/219 (5%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAE-------DLDKLRNDGYLMFQQVPMVE 59 L Y +IRG +IR LL ++E+ K+ D + L F +P + Sbjct: 4 LGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPYLI 63 Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119 +KL Q+ AIL YIA K+N+ G+ EK +D+ + DL L +S E+ Sbjct: 64 DGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEKLK 123 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179 L Q K R F + + VG+KL+ D ++L Sbjct: 124 PAYLEQLPGKLRQLSRFLG-----SRSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQG 178 Query: 180 LLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 L R L + +++ G K P+ + + K Sbjct: 179 NLSQFLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >1TU7-A nrPDB Length = 208 Score = 203 bits (516), Expect = 6e-53, Method: Composition-based stats. Identities = 61/209 (29%), Positives = 104/209 (49%), Gaps = 8/209 (3%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGM 63 KL Y +IRG E IR L ++F + I + +D +++ F Q+P + Sbjct: 2 SYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRI-AKDDFSSIKSQ--FQFGQLPCLYDGDQ 58 Query: 64 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLAL 123 ++VQ+ AIL ++A KYNL G++ E IDM+ EG+ DL + + E + Sbjct: 59 QIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETEKDPYI- 117 Query: 124 IQEKTKNRYFPAFEKVLKS--HGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 + FEK+L + +G++ ++G+K+S AD L E L + LD + FPLL Sbjct: 118 --KSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCLDKFPLL 175 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPMDE 210 K R+ + P +K++ + K P++ Sbjct: 176 KVFHQRMKDRPKLKEYCEKRDAAKVPVNG 204 >2GLR-A nrPDB Length = 209 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 58/210 (27%), Positives = 103/210 (49%), Gaps = 7/210 (3%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 + Y +RGR E++R LLA G ++E+ + + + + ++ Q+P E Sbjct: 1 PPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVV-TIDTWMQGLLKPTCLYGQLPKFEDGD 59 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 + L Q+ AIL ++ LYGK+ +E A +DM +G+ DL + L ++ E Sbjct: 60 LTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYV 119 Query: 123 LIQEKTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 K + FE +L + G+ ++VG+++S AD +L++LL + L + +FPL Sbjct: 120 ----KALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPL 175 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDE 210 L A R+S P +K FL P++ Sbjct: 176 LSAYVARLSARPKIKAFLSSPEHVNRPING 205 >4Q5F-A nrPDB Length = 218 Score = 200 bits (510), Expect = 3e-52, Method: Composition-based stats. Identities = 60/207 (28%), Positives = 102/207 (49%), Gaps = 9/207 (4%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 + KL Y +IRG E R + AGV+FE+ +K ED L+ F Q+P++E+DG Sbjct: 14 PQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLK-REDWPALKPK--TPFGQLPLLEVDG 70 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIAD----LGEMILLLPFSQPEEQD 118 L Q+ AI Y+ ++ L GK E+A +D + D L +L + +++ Sbjct: 71 EVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKE 130 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L + ++++ P EK L G +Y+VG ++ AD+ + + L E L +S Sbjct: 131 KVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFLSGH 190 Query: 179 PLLKALKTRISNLPTVKKFL--QPGSP 203 LK + LP +KK++ +P +P Sbjct: 191 LQLKKYIEHVRELPNIKKWIAERPKTP 217 >4Q5R-A nrPDB Length = 204 Score = 200 bits (509), Expect = 4e-52, Method: Composition-based stats. Identities = 64/211 (30%), Positives = 111/211 (52%), Gaps = 10/211 (4%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA KL Y ++ E IR+LL+ +FE+ + D L+ + F + P++EI Sbjct: 1 MAPSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEG-DWPNLKPS--MPFGKTPVLEI 57 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE-QDA 119 DG + Q+ AI Y+ ++ L GKD E IDM ++ I+D I + E + Sbjct: 58 DGKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQK 117 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DSSLISSF 178 K ++++T Y F++V+K++G YL KL+ AD + V +L Y+ + L+++ Sbjct: 118 KWDPLKKETIPYYTKKFDEVVKANGG-YLAAGKLTWADFYFVAILDYLNHMAKEDLVANQ 176 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPMD 209 P LKAL+ ++ LP +K ++ ++PP D Sbjct: 177 PNLKALREKVLGLPAIKAWVA----KRPPTD 203 >1FHE-A nrPDB Length = 217 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 54/210 (25%), Positives = 89/210 (42%), Gaps = 13/210 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEIDG 62 KL Y +RG + +R L E E+ + +D +K ++ + L +P D Sbjct: 3 KLGYWKLRGLAQPVR-LFLEYLGEEYEEHLYGRDDREKWMSEKFNMGLDLPNLPYYIDDK 61 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 KL Q+ AI+ YIA K+ + G +E+A I M DL + ++ Sbjct: 62 CKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNP-------KF 114 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 ++ + P K+ D YL G+ +S D L E L + L + FP Sbjct: 115 EEVKEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPK 174 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDE 210 LK K+RI LP +K +++ K P++ Sbjct: 175 LKEFKSRIEALPKIKAYMESKRFIKWPLNG 204 >1B8X-A nrPDB Length = 280 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 9/213 (4%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEI 60 P L Y I+G ++ R LL ++EE + E DK RN + L F +P Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDE-GDKWRNKKFELGLEFPNLPYYID 59 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 +KL Q+ AI+ YIA K+N+ G KE+A I M + D+ + + +S+ + + K Sbjct: 60 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSK-DFETLK 118 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + + + FE L + YL G+ ++ D L + L V +D + +FP Sbjct: 119 VDFLSKL--PEMLKMFEDRLC--HKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 174 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSL 213 L K RI +P + K+L+ P+ Sbjct: 175 LVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQA 207 >18GS-A nrPDB Length = 210 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 59/210 (28%), Positives = 101/210 (48%), Gaps = 7/210 (3%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 + Y +RGR ++R LLA G ++E+ + + E + ++ Q+P + Sbjct: 2 PPYTVVYFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGD 60 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 + L Q+ IL ++ LYGKD +E AL+DM +G+ DL + L ++ E Sbjct: 61 LTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYV 120 Query: 123 LIQEKTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 K FE +L + G+ ++VG+++S AD +L++LL E L + +FPL Sbjct: 121 ----KALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPL 176 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDE 210 L A R+S P +K FL P++ Sbjct: 177 LSAYVGRLSARPKLKAFLASPEYVNLPING 206 >3KXO-A nrPDB Length = 202 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 51/205 (24%), Positives = 103/205 (50%), Gaps = 10/205 (4%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 KL Y N+RGR E IR++ A +++E+ I+ A D ++++ L F ++P++E+DG Sbjct: 5 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKST--LPFGKIPILEVDG 61 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 + L Q+ AI Y+ +L G E+ +D ++ + D P+++ ++QD K Sbjct: 62 LTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCF---PWAE-KKQDVKEQ 117 Query: 123 LIQEKTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + E P + L ++ G+++L+GN ++ AD + + L+ + P Sbjct: 118 MFNELL-TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPR 176 Query: 181 LKALKTRISNLPTVKKFLQPGSPRK 205 L L+ ++ +P V +++ K Sbjct: 177 LVTLRKKVQAIPAVANWIKRRPQTK 201 >2WRT-A nrPDB Length = 218 Score = 197 bits (500), Expect = 5e-51, Method: Composition-based stats. Identities = 61/210 (29%), Positives = 97/210 (46%), Gaps = 13/210 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEIDG 62 KL Y IRG + +R LL G E+EE +D +K D + L +P D Sbjct: 4 KLGYWKIRGLQQPVRLLLEYLGEEYEEHLYG-RDDREKWLGDKFNMGLDLPNLPYYIDDK 62 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 KL Q+ AI+ YIA K+ + G +E+A I M DL + + + P+ ++ K Sbjct: 63 CKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCY-NPKFEEVKGD 121 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 ++E P K+ + D YL G+ +S D + E L + L + FP Sbjct: 122 YLKE------LPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPK 175 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDE 210 LK K+RI +LP +K +++ K P++ Sbjct: 176 LKEFKSRIEDLPKIKAYMESEKFIKWPLNS 205 >1DUG-A nrPDB Length = 234 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 9/213 (4%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEI 60 P L Y I+G ++ R LL ++EE + E DK RN + L F +P Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDE-GDKWRNKKFELGLEFPNLPYYID 59 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 +KL Q+ AI+ YIA K+N+ G KE+A I M + D+ + + +S+ + + K Sbjct: 60 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSK-DFETLK 118 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + + + FE L + YL G+ ++ D L + L V +D + +FP Sbjct: 119 VDFLSKL--PEMLKMFEDRLC--HKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 174 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSL 213 L K RI +P + K+L+ P+ Sbjct: 175 LVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQA 207 >1BG5-A nrPDB Length = 254 Score = 195 bits (496), Expect = 1e-50, Method: Composition-based stats. Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 9/213 (4%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMVEI 60 P L Y I+G ++ R LL ++EE + E DK RN + L F +P Sbjct: 2 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDE-GDKWRNKKFELGLEFPNLPYYID 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 +KL Q+ AI+ YIA K+N+ G KE+A I M + D+ + + +S+ + + K Sbjct: 61 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSK-DFETLK 119 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + + + FE L + YL G+ ++ D L + L V +D + +FP Sbjct: 120 VDFLSKL--PEMLKMFEDRLC--HKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 175 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSL 213 L K RI +P + K+L+ P+ Sbjct: 176 LVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQA 208 >1GSQ-A nrPDB Length = 202 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 60/204 (29%), Positives = 102/204 (50%), Gaps = 6/204 (2%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 K LHY + GR E R++LAA G EF ++ ++ A D L+ Y +P+++IDG Sbjct: 1 PKYTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMA-DWPNLKATMYS--NAMPVLDIDG 57 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 K+ Q+ I ++A ++ L GK EK +D E + D+ ++ + F+ PE + Sbjct: 58 TKMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFA-PEAAKEAVQ 116 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQ--DYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 EK+ R P E +L S+G + VGN ++ AD+H L + L+ P Sbjct: 117 QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPK 176 Query: 181 LKALKTRISNLPTVKKFLQPGSPR 204 + AL+ R++ P + +L+ R Sbjct: 177 IVALRKRVAECPKIAAYLKKRPVR 200 >5Y9Z-A nrPDB Length = 199 Score = 189 bits (480), Expect = 8e-49, Method: Composition-based stats. Identities = 53/205 (25%), Positives = 101/205 (49%), Gaps = 10/205 (4%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 KL Y N+RGR E IR++ A +++E+ I+ A D K++ L F ++P++E++G Sbjct: 2 PNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQA-DWPKIKPT--LPFGKIPVLEVEG 58 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 + L Q+ AI Y+ +L GK E+ +D ++ + D + P+++ E QD K Sbjct: 59 LTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLF---PWAE-ENQDLKER 114 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + R P K L ++ D + +GN ++ AD + + L L+ +P Sbjct: 115 TFNDLL-TRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPR 173 Query: 181 LKALKTRISNLPTVKKFLQPGSPRK 205 L +L+ ++ +P + ++ K Sbjct: 174 LVSLRNKVQAIPAISAWILKRPQTK 198 >4Q5Q-A nrPDB Length = 219 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 58/213 (27%), Positives = 95/213 (44%), Gaps = 22/213 (10%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKF--IKSAEDLDK--LRNDGY---LMFQQVP 56 +P L Y +IRG + IR LL +GV+F +K I A D D+ N+ + L F +P Sbjct: 3 QPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLP 62 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE 116 MK+ QT AIL Y+ KY L G + E+ I M + D+ ++ + + Sbjct: 63 YYIDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCY----- 117 Query: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELD 171 +K K Y + LK + ++ G +S D +L E L +V+ + Sbjct: 118 -----DANCDKLKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMV 172 Query: 172 SSLISSFPLLKALKTRISNLPTVKKFLQPGSPR 204 + F LK R+ +LP V +++ P+ Sbjct: 173 PEVFGQFENLKRYVERMESLPRVSDYIKKQQPK 205 >2AAW-A nrPDB Length = 222 Score = 187 bits (474), Expect = 4e-48, Method: Composition-based stats. Identities = 59/208 (28%), Positives = 100/208 (48%), Gaps = 15/208 (7%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAED----LDKLRNDGYLMFQQVP 56 M + L+Y + RG+ E IR + A G+E+ +K D + + F+QVP Sbjct: 12 MGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVP 71 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE 116 +++I + L Q++AI+ Y++ KYN+ G+ + DM G+ D+ + E Sbjct: 72 ILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNE 131 Query: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQD------YLVGNKLSRADIHLVELLYYVEEL 170 + ++ FEK+LK + + Y VGN L+ AD+ + L +E Sbjct: 132 -----TTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETK 186 Query: 171 DSSLISSFPLLKALKTRISNLPTVKKFL 198 S + +FPLLKA ISNLP +K ++ Sbjct: 187 YPSSLKNFPLLKAHNEFISNLPNIKNYI 214 >4WR5-A nrPDB Length = 244 Score = 186 bits (472), Expect = 7e-48, Method: Composition-based stats. Identities = 54/210 (25%), Positives = 95/210 (45%), Gaps = 9/210 (4%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY---LMFQQVPMV 58 + P L Y I+G ++ R LL + E+ + ++ DK RN + L F +P Sbjct: 24 SXSPILGYWKIKGLVQPTRLLLEXLEEK-YEEHLXERDEGDKWRNKKFELGLEFPNLPYX 82 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 +KL Q+ AI+ IA K+N+ G KE+A I M + D+ + + +S+ + + Sbjct: 83 IDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSK-DFET 141 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 K+ + + FE L + L G+ ++ D L + L V +D + +F Sbjct: 142 LKVDFLSKL--PEMLKMFEDRLC--HKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAF 197 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPM 208 P L K RI +P + K+L+ P+ Sbjct: 198 PKLVCFKKRIEAIPQIDKYLKSSKYIAWPL 227 >1ZL9-A nrPDB Length = 207 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 58/210 (27%), Positives = 97/210 (46%), Gaps = 22/210 (10%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGM 63 KL Y N RG E R + A AG ++E+ + + E L+ F Q+P +E+DG Sbjct: 3 SYKLTYFNGRGAGEVSRQIFAYAGQQYEDNRV-TQEQWPALKETCAAPFGQLPFLEVDGK 61 Query: 64 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEM-----ILLLPFSQPEEQD 118 KL Q+ AI ++A ++ L GK E+A ++ + D ++ F + + Sbjct: 62 KLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPGDVET 121 Query: 119 AKLALIQEKTKNRYFPAFEK-------VLKSHGQDYLVGNKLSRADIHLVELLYYVEELD 171 K K+ + PAFEK LK+ G +LVG+ L+ D+ + + + Sbjct: 122 LK--------KDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSADL-IAK 172 Query: 172 SSLISSFPLLKALKTRISNLPTVKKFLQPG 201 S FP LKA +I +P +KK+++ Sbjct: 173 GGDFSKFPELKAHAEKIQAIPQIKKWIETR 202 >1M0U-A nrPDB Length = 249 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 43/200 (21%), Positives = 94/200 (47%), Gaps = 6/200 (3%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGM 63 L Y N++ E +R+L A E+E+ + E L+ + Q+P++E+DG Sbjct: 49 SYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDE-WPALKPT--MPMGQMPVLEVDGK 105 Query: 64 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE-QDAKLA 122 ++ Q+ ++ ++A L G E ID+ ++ I D I ++ + +E ++ KL Sbjct: 106 RVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDEIKEKKLV 165 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DSSLISSFPLL 181 + + Y E+ +K + +G KL+ AD++ + Y+ + L+ +P L Sbjct: 166 TLNAEVIPFYLEKLEQTVKDNDGHLALG-KLTWADVYFAGITDYMNYMVKRDLLEPYPAL 224 Query: 182 KALKTRISNLPTVKKFLQPG 201 + + ++ L +K +++ Sbjct: 225 RGVVDAVNALEPIKAWIEKR 244 >1YQ1-A nrPDB Length = 208 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 55/204 (26%), Positives = 93/204 (45%), Gaps = 7/204 (3%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 KL Y RG E IR L AGV+FEE + D L +Q+P++ IDG Sbjct: 2 PSYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMN--PDQTWLDIKDSTPMKQLPVLNIDG 59 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMIL-----LLPFSQPEEQ 117 +L Q+ AIL Y+A K+ GK +E+A +D + D EE Sbjct: 60 FELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSAEEV 119 Query: 118 DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 + + +N YF +L+ +L+G+ ++ AD+ +V+ L ++ S Sbjct: 120 EKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGLFDESE 179 Query: 178 FPLLKALKTRISNLPTVKKFLQPG 201 F L AL+ ++++ P +K+++ Sbjct: 180 FTKLAALREKVNSYPGIKEYIAKR 203 >2CA8-A nrPDB Length = 211 Score = 170 bits (430), Expect = 5e-43, Method: Composition-based stats. Identities = 53/204 (25%), Positives = 98/204 (48%), Gaps = 10/204 (4%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 + K+ Y N RGR ESIR L AAGV +E++ I S +D K++ + ++P V+I Sbjct: 3 GDHIKVIYFNGRGRAESIRMTLVAAGVNYEDERI-SFQDWPKIKPT--IPGGRLPAVKIT 59 Query: 62 GMK-----LVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE 116 +V++ AI Y+A K+++ G +E ++ I DL EE Sbjct: 60 DNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEE 119 Query: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS 176 + + I + LK+ VG+K++ AD+ L+ ++ +V +LD ++ Sbjct: 120 KQKIIKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLT 179 Query: 177 -SFPLL-KALKTRISNLPTVKKFL 198 +P + K + +++ P + K+L Sbjct: 180 GKYPEIHKHRENLLASSPRLAKYL 203 >1U3I-A nrPDB Length = 211 Score = 167 bits (424), Expect = 3e-42, Method: Composition-based stats. Identities = 53/212 (25%), Positives = 102/212 (48%), Gaps = 11/212 (5%) Query: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID 61 E K+ Y + RGR ESIR L AAGV++E++ I S +D K++ + ++P V++ Sbjct: 3 GEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERI-SFQDWPKIKPT--IPGGRLPAVKVT 59 Query: 62 GMK-----LVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE 116 ++++ AI Y+A K+++ G+ +E ++ I D+ EE Sbjct: 60 DDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEE 119 Query: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS 176 ++ I F + LK VG+K++ AD+ L+ ++ +V +LD ++ Sbjct: 120 KEKITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGFLT 179 Query: 177 -SFPLL-KALKTRISNLPTVKKFLQPGSPRKP 206 +P + K + +++ P + K+L P P Sbjct: 180 GKYPEIHKHRENLLASSPRLAKYL-SNRPATP 210 >2WDU-A nrPDB Length = 211 Score = 164 bits (415), Expect = 3e-41, Method: Composition-based stats. Identities = 50/211 (23%), Positives = 94/211 (44%), Gaps = 12/211 (5%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG- 62 KL Y RGR E IR LL AGV+FE+ + ++ L +VP++++ G Sbjct: 5 HFKLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTM-DQWPTIKPT--LPGGRVPLLDVTGP 61 Query: 63 ----MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 + ++ AI +A ++ + G+ +E LI+ I DL + + + E++ Sbjct: 62 DGKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGEKE 121 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS-S 177 AK+ +E + L+S G ++ GN+++ D+ L L +V E + Sbjct: 122 AKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVPGFLEQK 181 Query: 178 FPLLKALKTRI-SNLPTVKKFLQPGSPRKPP 207 FP L + ++ + ++L+ K P Sbjct: 182 FPKLHEFHKSLPTSCSRLSEYLKKR--AKTP 210 >2HNL-A nrPDB Length = 225 Score = 161 bits (407), Expect = 3e-40, Method: Composition-based stats. Identities = 56/202 (27%), Positives = 99/202 (49%), Gaps = 10/202 (4%) Query: 3 EKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDG 62 EK L Y N RGR E IR L A A V +E+ I E L+ F VPM+ + G Sbjct: 26 EKYTLTYFNGRGRAEVIRLLFALANVSYEDNRITRDE-WKYLKPR--TPFGHVPMLNVSG 82 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 L ++ AI + ++ L G + E+A I + I +L + + +P++ + K Sbjct: 83 NVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKL--IPWTHEKNTTKKAE 140 Query: 123 LIQEKTKNRYFPA---FEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179 L + +++ P +EK LK ++VGNK+S AD+ + +L ++ D + +P Sbjct: 141 LFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLD--DEVKLEEYP 198 Query: 180 LLKALKTRISNLPTVKKFLQPG 201 L + +I +P +K++++ Sbjct: 199 QLASFVNKIGQMPGIKEWIKKR 220 >2CZ2-A nrPDB Length = 223 Score = 153 bits (388), Expect = 4e-38, Method: Composition-based stats. Identities = 57/213 (26%), Positives = 99/213 (46%), Gaps = 14/213 (6%) Query: 2 AEKPKLHYSNIRGRME-SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPM 57 A KP L YS R +R LA G+++E I +D + + + +QVP Sbjct: 10 AGKPIL-YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 68 Query: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQP 114 ++IDG+ +VQ+ AI+ Y+ L +D +++A++ M + IA + + L + Sbjct: 69 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 128 Query: 115 EEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 Q+ ++ Q K F A EK+L+S Y VG+++S AD+ LV + E Sbjct: 129 VGQENQMQWAQ-KVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD- 186 Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 +S +P + + + L Q PR+ P Sbjct: 187 LSPYPTISHINKELLALE----VFQVSHPRRQP 215 >1FW1-A nrPDB Length = 216 Score = 153 bits (388), Expect = 4e-38, Method: Composition-based stats. Identities = 52/213 (24%), Positives = 97/213 (45%), Gaps = 14/213 (6%) Query: 2 AEKPKLHYSNIRGRME-SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPM 57 A KP L YS R +R LA G++++ I +D + + + +QVP Sbjct: 3 AGKPIL-YSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPT 61 Query: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQP 114 ++IDG+ + Q+ AI+ Y+ L +D K++A + M + IA + + L + Sbjct: 62 LKIDGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQ 121 Query: 115 EEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 ++ +L Q F A E++L+S Y VG++++ AD+ LV + E Sbjct: 122 VGEEMQLTWAQNAITCG-FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVD- 179 Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 ++ +P + ++ R+ L Q P + P Sbjct: 180 LTPYPTISSINKRLLVLEAF----QVSHPCRQP 208 >3LSZ-A nrPDB Length = 225 Score = 126 bits (318), Expect = 5e-30, Method: Composition-based stats. Identities = 52/212 (24%), Positives = 87/212 (41%), Gaps = 25/212 (11%) Query: 9 YSNIRGRMESIRWLLAAAGVEFEEKFIKSA---------EDLDKLRNDGYL---MFQQVP 56 Y R R WLLA + FE + A E + YL Q+P Sbjct: 6 YGVYRSRASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPLGQIP 65 Query: 57 MVEIDGMKLVQTRAILNYIASKYN--LYGKDIKEKALIDMY-------IEGIADLGEMIL 107 +E +G+ L ++ AI +IA L + E AL+ + +E A ++I Sbjct: 66 CLEEEGLILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQ 125 Query: 108 LLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYV 167 E A +A+ E+ + R E+ + +DYLVG + + AD++L E L Y Sbjct: 126 RSGGGTSPEGQAAIAIAAERLR-RPLARLERHFAA--EDYLVGGRFTVADLNLAETLRY- 181 Query: 168 EELDSSLISSFPLLKALKTRISNLPTVKKFLQ 199 + +L+ FP + A R + P + ++ Sbjct: 182 GQAHPALLEPFPAVAAWLDRCQSRPAFRLMME 213 >5F07-A nrPDB Length = 213 Score = 126 bits (317), Expect = 8e-30, Method: Composition-based stats. Identities = 57/193 (29%), Positives = 90/193 (46%), Gaps = 21/193 (10%) Query: 23 LAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPMVEIDGMKLVQTRAILNYIASKY 79 L GVEF+ + D + + +L F QVP+VE KL ++RAI+ Y A+KY Sbjct: 20 LLEKGVEFDLVHVDL--DSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKY 77 Query: 80 -----NLYGKDIKEKALIDMYIEGIA-DLGEMILLLPFSQ------PEEQDAKLALIQEK 127 NL G ++EKAL+D ++E A + +++ + F ++ D++L E+ Sbjct: 78 EDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQGDSELVRTYEE 137 Query: 128 TKNRYFPAFEKVLKSHGQDYLVGNKLSRADI-HLVELLYYVEELD-SSLISSFPLLKALK 185 + +EK L YL G+ + AD+ HL Y V E L+ L A Sbjct: 138 KLEKVLDVYEKRLSKS--KYLAGDSFTLADLSHLPATRYLVNEAGLGHLVKDRKKLNAWW 195 Query: 186 TRISNLPTVKKFL 198 IS+ P KK + Sbjct: 196 EDISSRPAWKKLM 208 >4PNG-A nrPDB Length = 229 Score = 123 bits (310), Expect = 4e-29, Method: Composition-based stats. Identities = 44/183 (24%), Positives = 83/183 (45%), Gaps = 11/183 (6%) Query: 18 SIRWLLAAAGVEFE--EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 +++ LAA V +E E ++ E+ + VP +E DG + + AI+ Y+ Sbjct: 23 AVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKN-PQHTVPTLEDDGHYIWDSHAIIAYL 81 Query: 76 ASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEK--TK 129 SKY LY KD+ ++A++D + + + L ++P + + +E+ Sbjct: 82 VSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIPKERYDAI 141 Query: 130 NRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRIS 189 + EK L G DY+ GN+L+ AD ++ + +E + +P + A R+ Sbjct: 142 IEVYDFLEKFLA--GNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFKRLQ 199 Query: 190 NLP 192 LP Sbjct: 200 KLP 202 >5EY6-A nrPDB Length = 217 Score = 121 bits (303), Expect = 3e-28, Method: Composition-based stats. Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 28/204 (13%) Query: 17 ESIRWLLAAAGVEFEEKFIKS------AEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRA 70 + L V F+ + D K++ F QVP + + + L ++R+ Sbjct: 16 SRVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQ-----PFGQVPAFQDESISLFESRS 70 Query: 71 ILNYIASKY------NLYGKDIKEKALIDMYIEGIAD-----LGEMILLLPFSQPEE--Q 117 I Y+ KY LYG + E+A ID ++E G ++ L F+ Q Sbjct: 71 ICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQ 130 Query: 118 DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADI-HLVELLYYVEELDS-SLI 175 D + E+ + +E+ L +L G++ + AD+ HL Y V D L Sbjct: 131 DQGVIKQNEEKLGKVLDIYEQRLGES--RFLAGDEFTFADLSHLPNGDYLVNATDKGHLF 188 Query: 176 SSFPLLKALKTRISNLPTVKKFLQ 199 +S + IS+ + KK ++ Sbjct: 189 TSRENVGRWWNEISDRESWKKVIE 212 >4YH2-A nrPDB Length = 222 Score = 111 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 11/183 (6%) Query: 18 SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQ--VPMVEIDGMKLVQTRAILNYI 75 +++ LAA + +E + +L + Q VP +E DG + + AI+ Y+ Sbjct: 17 AVKLTLAALNLTYEYVNV-DIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYL 75 Query: 76 ASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEK--TK 129 SKY LY KD ++A++D + + + + S+ + + +E+ Sbjct: 76 VSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAI 135 Query: 130 NRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRIS 189 + E LK GQDY+ GN+L+ AD LV + +E + + +P + A ++ Sbjct: 136 IEIYDFVETFLK--GQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLE 193 Query: 190 NLP 192 LP Sbjct: 194 QLP 196 >4RI7-A nrPDB Length = 215 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 49/165 (29%), Positives = 74/165 (44%), Gaps = 16/165 (9%) Query: 48 GYLMFQQVPMVEIDGMKLVQTRAILNYIASKY------NLYGKDIKEKALIDMYIEGIA- 100 F QVP + + + L ++RAI YI KY +LYG DI KA ID ++E Sbjct: 49 KIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQ 108 Query: 101 ----DLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRA 156 G+++ L FS +A + +K + +E+ L +L G++ S A Sbjct: 109 TFGPPSGDLVHDLLFSSVPVDEALIKKNVDKL-AKVLDIYEQKLGQT--RFLAGDEFSFA 165 Query: 157 DI-HLVELLYYVEELDSS-LISSFPLLKALKTRISNLPTVKKFLQ 199 D+ HL Y V D L +S + T ISN + KK L+ Sbjct: 166 DLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLE 210 >5F06-A nrPDB Length = 216 Score = 108 bits (269), Expect = 3e-24, Method: Composition-based stats. Identities = 48/199 (24%), Positives = 85/199 (42%), Gaps = 19/199 (9%) Query: 23 LAAAGVEFEEKFIKSAEDLDKLRN-DGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNL 81 L ++FE + K F Q+P +E D + L ++RAI +YIA K+ Sbjct: 20 LHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDLTLFESRAITSYIAEKFKG 79 Query: 82 YG------KDIKEKALIDMYIE--------GIADLGEMILLLPFSQPEEQDAKLALIQEK 127 G +++KE A + ++ E IA + ++ P + D + + Sbjct: 80 TGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMVAPL-RGNSPDQTIIDDNVE 138 Query: 128 TKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELD-SSLISSFPLLKALKT 186 + +E L S YL G+ S AD+H + YY+ + +S+++ P +KA Sbjct: 139 KLGKVLDIYEAKLSST--KYLAGDFYSLADLHHLPYTYYLMKTPAASVVNERPHVKAWWE 196 Query: 187 RISNLPTVKKFLQPGSPRK 205 IS+ P KK + + K Sbjct: 197 DISSRPAFKKVAEGMNFVK 215 >1AXD-A nrPDB Length = 209 Score = 101 bits (252), Expect = 2e-22, Method: Composition-based stats. Identities = 46/190 (24%), Positives = 86/190 (45%), Gaps = 20/190 (10%) Query: 23 LAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPMVEIDGMKLVQTRAILNYIASKY 79 L AG ++E I A + ++ +L F QVP ++ + L ++RAI Y A K Sbjct: 21 LEEAGSDYEIVPINFAT--AEHKSPEHLVRNPFGQVPALQDGDLYLFESRAICKYAARKN 78 Query: 80 N---LYGKDIKEKALIDMYIE--------GIADLGEMILLLPFSQPEEQDAKLALIQEKT 128 L +++E A++D++IE + + +L+ P + EK Sbjct: 79 KPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDENLEKL 138 Query: 129 KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELD-SSLISSFPLLKALKTR 187 K + +E L YL G+ LS AD++ V + + +S++ ++P +KA + Sbjct: 139 K-KVLEVYEARLTKC--KYLAGDFLSLADLNHVSVTLCLFATPYASVLDAYPHVKAWWSG 195 Query: 188 ISNLPTVKKF 197 + P+V+K Sbjct: 196 LMERPSVQKV 205 >1F2E-A nrPDB Length = 201 Score = 100 bits (250), Expect = 5e-22, Method: Composition-based stats. Identities = 49/182 (26%), Positives = 79/182 (43%), Gaps = 15/182 (8%) Query: 23 LAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID-GMKLVQTRAILNYIASKYNL 81 A V+ + ++ ED + +VP + +D G L + AIL YIA + Sbjct: 25 FEAVKVDLAVRKTEAGEDFLTVNPS-----GKVPALTLDSGETLTENPAILLYIADQNPA 79 Query: 82 YGKDIKEKALIDMY--IEGIADLGEMI--LLLPFSQPEEQDAKLALIQEKTKNRYFPAFE 137 G E +L D Y + ++ LG +P P D A E KN + A + Sbjct: 80 SGLAPAEGSL-DRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKN-HLAALD 137 Query: 138 KVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKF 197 K L G+D+ GN S ADI+L +L + + + +++P L A +I+ P V Sbjct: 138 KELA--GRDHYAGNAFSVADIYLYVMLGWPAYVGIDM-AAYPALGAYAGKIAQRPAVGAA 194 Query: 198 LQ 199 L+ Sbjct: 195 LK 196 >6F05-A nrPDB Length = 215 Score = 97.3 bits (241), Expect = 5e-21, Method: Composition-based stats. Identities = 47/205 (22%), Positives = 81/205 (39%), Gaps = 19/205 (9%) Query: 16 MESIRWL--LAAAGVEFEEKFIKSAEDLDKLRNDGYL-MFQQVPMVEIDGMKLVQTRAIL 72 R L L GV FE + + K L F VP V K+ ++RA++ Sbjct: 11 ASPKRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVM 70 Query: 73 NYIASKY-----NLYGKDIKEKALIDMYIEGIA-----DLGEMILLLPFSQ--PEEQDAK 120 Y+A KY +L GK ++++ ++ +++ A L + L + F+ D K Sbjct: 71 RYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEK 130 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVE--ELDSSLISSF 178 L E+ +E L YL G+ +S AD+ + Y+ + +I Sbjct: 131 LIKESEEKLAGVLDVYEAHLSKS--KYLAGDFVSLADLAHLPFTDYLVGPIGKAYMIKDR 188 Query: 179 PLLKALKTRISNLPTVKKFLQPGSP 203 + A IS+ P K+ + S Sbjct: 189 KHVSAWWDDISSRPAWKETVAKYSF 213 >3VWX-A nrPDB Length = 222 Score = 96.1 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 44/185 (23%), Positives = 77/185 (41%), Gaps = 12/185 (6%) Query: 18 SIR---WLLAAAGVEFEEKFIKS-AEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILN 73 +R L A + FE K + A++ VP +E DG + + AI+ Sbjct: 14 PVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWDSHAIMA 73 Query: 74 YIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTK 129 Y+ SKY LY KD+ ++A++D + A + L + P + + Q + Sbjct: 74 YLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQIPQHQID 133 Query: 130 NRY--FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTR 187 + + E LK++ Y+ G+ L+ AD +V + + S FP L A Sbjct: 134 SIVESYGFLESFLKNN--KYMAGDHLTIADFSIVTSVTSLVAFAEIDQSKFPKLSAWLKS 191 Query: 188 ISNLP 192 + +LP Sbjct: 192 LQSLP 196 >1AW9-A nrPDB Length = 216 Score = 90.7 bits (224), Expect = 4e-19, Method: Composition-based stats. Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 28/206 (13%) Query: 22 LLAAAGVEFEEKFIKS------AEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 +L G++FE + D L F Q+P + L ++RAI YI Sbjct: 20 VLNEKGLDFEIVPVDLTTGAHKQPDFLALN-----PFGQIPALVDGDEVLFESRAINRYI 74 Query: 76 ASKYNLYGKDIK----EKALIDMYIE--------GIADLGEMILLLPFSQPEEQDAKLAL 123 ASKY G D+ A +++++E + L +L+ P DA + Sbjct: 75 ASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNASPLVFQLLVRPLL-GGAPDAAVVD 133 Query: 124 IQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DSSLISSFPLLK 182 + + +E L + YL G++ + AD + L Y+ + + L+++ P +K Sbjct: 134 KHAEQLAKVLDVYEAHLARN--KYLAGDEFTLADANHASYLLYLSKTPKAGLVAARPHVK 191 Query: 183 ALKTRISNLPTVKKFLQPGSPRKPPM 208 A I P +K + P PP Sbjct: 192 AWWEAIVARPAFQKTVA-AIPLPPPP 216 >1E6B-A nrPDB Length = 221 Score = 87.6 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 41/215 (19%), Positives = 84/215 (39%), Gaps = 15/215 (6%) Query: 3 EKPKLHYSNIRGRM-ESIRWLLAAAGVEFEEKFIK--SAEDLDKLRNDGYLMFQQVPMVE 59 EK KL YS R +R LA G+++E + + D VP + Sbjct: 7 EKLKL-YSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDF-KKINPMGTVPALV 64 Query: 60 IDGMKLVQTRAILNYIASKY---NLYGKDIKEKAL----IDMYIEGIADLGEMILLLPFS 112 + + + AI+ Y+ KY L +D+ ++A+ + + + GI + + ++ + Sbjct: 65 DGDVVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQP-HQNLAVIRYI 123 Query: 113 QPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELL-YYVEELD 171 + + + + F A EK+L + + G+++ AD+ L + + Sbjct: 124 EEKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQ 183 Query: 172 SSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKP 206 ++ +P L + LP + L P P Sbjct: 184 INM-EPYPTLAKCYESYNELPAFQNALPEKQPDAP 217 >5F05-A nrPDB Length = 212 Score = 84.2 bits (207), Expect = 4e-17, Method: Composition-based stats. Identities = 45/195 (23%), Positives = 68/195 (34%), Gaps = 15/195 (7%) Query: 17 ESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL-MFQQVPMVEIDGMKLVQTRAILNYI 75 + + L VEFE + K L F QVP +KL ++RAI Y+ Sbjct: 15 QRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQYV 74 Query: 76 ASKYNLYGKDIKE----KALIDMYIE----GIADLGEMILLLPFSQPEE---QDAKLALI 124 A +Y G + A I ++ E ++ +P DA L Sbjct: 75 AHQYASKGTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFKPVFGLPTDAALVAE 134 Query: 125 QEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADI-HLVELLYYVEELDSSLISSFPLLKA 183 E T + +E L YL + + AD+ HL + + L S P + A Sbjct: 135 TEVTLGKVLDVYEARLSQS--KYLASDSFTLADLHHLPNIQALLGTPSKKLFDSRPHVSA 192 Query: 184 LKTRISNLPTVKKFL 198 I+ P K L Sbjct: 193 WVASITGRPAWGKVL 207 >1PN9-A nrPDB Length = 209 Score = 84.2 bits (207), Expect = 4e-17, Method: Composition-based stats. Identities = 39/189 (20%), Positives = 70/189 (37%), Gaps = 10/189 (5%) Query: 8 HYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQ--VPMVEIDGMKL 65 +Y +++ AA GVE K + + ++ + + Q +P + +G L Sbjct: 4 YYLPGSAPCRAVQMTAAAVGVELNLKLTDLMK-GEHMKPEFLKLNPQHCIPTLVDNGFAL 62 Query: 66 VQTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 ++RAI Y+A KY LY KD +++A+++ + Sbjct: 63 WESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFAKQPA 122 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 EK L+ GQ+Y GN L+ AD+ L + E + +P + Sbjct: 123 NPENEKKMKDAVGFLNTFLE--GQEYAAGNDLTIADLSLAATIATYEV-AGFDFAPYPNV 179 Query: 182 KALKTRISN 190 A R Sbjct: 180 AAWFARCKA 188 >1JLV-A nrPDB Length = 209 Score = 84.2 bits (207), Expect = 4e-17, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 67/185 (36%), Gaps = 8/185 (4%) Query: 8 HYSNIRGRMESIRWLLAAAGVEFEEKFIK-SAEDLDKLRNDGYLMFQQVPMVEIDGMKLV 66 +Y +++ AA GVE K A + K +P + +G L Sbjct: 4 YYLPGSAPCRAVQMTAAAVGVELNLKLTNLMAGEHMKPEFLKINPQHCIPTLVDNGFALW 63 Query: 67 QTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 ++RAI Y+A KY LY KD +++A+++ + + Sbjct: 64 ESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYPQIFAKQPAN 123 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182 EK L G Y+ G+ L+ AD+ ++ + + ++ +P + Sbjct: 124 AENEKKMKDAVDFLNTFLD--GHKYVAGDSLTIADLTVLATVSTYDV-AGFELAKYPHVA 180 Query: 183 ALKTR 187 A R Sbjct: 181 AWYER 185 >2IL3-A nrPDB Length = 221 Score = 83.8 bits (206), Expect = 5e-17, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 73/183 (39%), Gaps = 9/183 (4%) Query: 16 MESIRWLLAAAGVEFEEKFIKS-AEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNY 74 ++ A G+E E+K I D K +P+++ +G + ++ AI+ Y Sbjct: 15 CRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVLDDNGTIITESHAIMIY 74 Query: 75 IASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQP-EEQDAKLALIQEKTK 129 + +KY LY KD ++A ++ + + + + F + + + + + Sbjct: 75 LVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFGKSDIPEDRVEYV 134 Query: 130 NRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRIS 189 + + E L D++ G ++ AD + + + + S P + A R+ Sbjct: 135 QKSYELLEDTLVD---DFVAGPTMTIADFSCISTISSIMGVVPLEQSKHPRIYAWIDRLK 191 Query: 190 NLP 192 LP Sbjct: 192 QLP 194 >5A5K-A nrPDB Length = 212 Score = 83.4 bits (205), Expect = 6e-17, Method: Composition-based stats. Identities = 39/195 (20%), Positives = 71/195 (36%), Gaps = 23/195 (11%) Query: 18 SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPMVEIDGMKLVQTRAILNY 74 + L ++FE ++ + + + + +L F QVP E +KL ++RAI Y Sbjct: 17 RVLIALHEKNLDFELVHVELKD--GEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQY 74 Query: 75 IASKYNLYGKDIKE-------KALIDMYIEGIAD--LGEMILLLPFSQ------PEEQDA 119 IA +Y G ++ + + I + D + L F Q D Sbjct: 75 IAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDE 134 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELD-SSLISSF 178 + +E + +E LK YL G + D+H + + Y+ L + Sbjct: 135 AVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTER 192 Query: 179 PLLKALKTRISNLPT 193 P + I+ P Sbjct: 193 PRVNEWVAEITKRPA 207 >3UAR-A nrPDB Length = 227 Score = 81.5 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 49/206 (23%), Positives = 84/206 (40%), Gaps = 22/206 (10%) Query: 6 KLHYSNIRGRME-SIRWLLAAAGVEFE-------EKFIKSAEDLDKLRNDGYLMFQQVPM 57 KL+Y G + +L AG++FE K S D ++ GY+ Q+ Sbjct: 4 KLYYFP--GACSLAPHIVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQL-- 59 Query: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIK----EKALIDMYIEGIADLGEMILLLPFSQ 113 DG L + + IL Y+A G E+ + ++ I+ PF Sbjct: 60 --DDGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFG-PFWN 116 Query: 114 PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSS 173 PE +A + +R E L++ G +L+G++ S AD +L +L + E L Sbjct: 117 PESPEASKQIALGLL-SRRLDYVEDRLEA-GGPWLMGDRYSVADAYLSTVLGWCEYLKID 174 Query: 174 LISSFPLLKALKTRISNLPTVKKFLQ 199 +S +P + A R P V+ ++ Sbjct: 175 -LSKWPRILAYLERNQARPAVQAAMK 199 >4IGJ-A nrPDB Length = 242 Score = 81.1 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 44/214 (20%), Positives = 82/214 (38%), Gaps = 12/214 (5%) Query: 9 YSNIRGR-MESIRWLLAAAGVEFEEKFIKS-AEDLDKLRNDGYLMFQQVPMVEI--DGMK 64 YS R +R LA G+ +E + + A++ + + QVP++E+ DG Sbjct: 28 YSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRT 87 Query: 65 --LVQTRAILNYIASKYN---LYGKDIKEKALIDMYIEGIADLGEMILL-LPFSQPEEQD 118 LVQ+ AIL ++ ++ L D+ +A + E + + + L E+ Sbjct: 88 HLLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLREKV 147 Query: 119 AKLALIQEKT-KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 + R A E ++ + G+ + AD +LV LY + Sbjct: 148 PGWDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLD-LEP 206 Query: 178 FPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEK 211 +P L+ + + L + P PP D + Sbjct: 207 YPTLRRVDEACAALAPFQAAHPDRQPDAPPPDRR 240 >5ZWP-A nrPDB Length = 208 Score = 79.5 bits (195), Expect = 9e-16, Method: Composition-based stats. Identities = 38/182 (20%), Positives = 65/182 (35%), Gaps = 8/182 (4%) Query: 8 HYSNIRGRMESIRWLLAAAGVEFEEKFIK-SAEDLDKLRNDGYLMFQQVPMVEIDGMKLV 66 +Y S+ A G+E +K + A + K +P + L Sbjct: 4 YYLPGSAPCRSVLMTAKALGIELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDGDFALW 63 Query: 67 QTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 ++RAI+ Y+ KY L+ K K++A+I+ + + A Sbjct: 64 ESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPAD 123 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182 K F LK G +Y G+ L+ AD+ L+ + E S IS +P + Sbjct: 124 PELFKKIETAFDFLNTFLK--GHEYAAGDSLTVADLALLASVSTFEV-ASFDISKYPNVA 180 Query: 183 AL 184 Sbjct: 181 KW 182 >2GDR-A nrPDB Length = 202 Score = 79.5 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 25/213 (11%) Query: 6 KLHYSNIRGRME-SIRWLLAAAGVEFE-------EKFIKSAEDLDKLRNDGYLMFQQVPM 57 KL+YS G S L AG+ FE K S +D ++ GY VP Sbjct: 2 KLYYSP--GACSLSPHIALREAGLNFELVQVDLASKKTASGQDYLEVNPAGY-----VPC 54 Query: 58 VE-IDGMKLVQTRAILNYIASKYN---LYGKD-IKEKALIDMYIEGIADLGEMILLLPFS 112 ++ DG L + AI+ Y+A + L + E+ + ++ I+ P Sbjct: 55 LQLDDGRTLTEGPAIVQYVADQVPGKQLAPANGSFERYHLQQWLNFISSELHKSFS-PLF 113 Query: 113 QPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS 172 P D ++ N + L+ YL+G++LS ADI+L +L + ++ Sbjct: 114 NPASSDE-WKNAVRQSLNTRLGQVARQLE--HAPYLLGDQLSVADIYLFVVLGWSAYVNI 170 Query: 173 SLISSFPLLKALKTRISNLPTVKKFLQPGSPRK 205 +S +P L+A + R+ V+ L+ K Sbjct: 171 D-LSPWPSLQAFQGRVGGREAVQSALRAEGLIK 202 >3M3M-A nrPDB Length = 210 Score = 77.6 bits (190), Expect = 4e-15, Method: Composition-based stats. Identities = 43/195 (22%), Positives = 76/195 (38%), Gaps = 15/195 (7%) Query: 9 YSNIR-GRMESIRWLLAAAGVEFEEKFIK-SAEDLDKLRNDGYLMFQQVPMVEI-DGMKL 65 Y + R G I+ +L G+ +E + + D ++P++E+ DG L Sbjct: 7 YGDYRSGNCYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELEDGTCL 66 Query: 66 VQTRAILNYIASKYNLYGKDIKEKALIDMY-------IEGIADLGEMILLLPFSQPEEQD 118 ++ AILN++A + + + + + E + I L E ++ Sbjct: 67 WESNAILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGLPEERRE 126 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 L L + K EK L YLVG S ADI L +V + +S + Sbjct: 127 EYLKLHKRGYKA--LDVMEKQLSRT--PYLVGEHYSIADIALY-AYTHVADEGGFDLSRY 181 Query: 179 PLLKALKTRISNLPT 193 P ++A R+ + P Sbjct: 182 PGIQAWMQRVQSHPR 196 >5F0G-A nrPDB Length = 215 Score = 76.5 bits (187), Expect = 8e-15, Method: Composition-based stats. Identities = 34/183 (18%), Positives = 73/183 (39%), Gaps = 10/183 (5%) Query: 8 HYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRND--GYLMFQQVPMVEIDGMKL 65 +Y G ++ + A G+E +K + + E ++L+ + +P + +G + Sbjct: 4 YYMPGGGGCRTVIMVAKALGLELNKKLLNTME-GEQLKPEFVKLNPQHTIPTLVDNGFSI 62 Query: 66 VQTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 ++RAI Y+ KY L D K++A+I+ + + Sbjct: 63 WESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTGKPG 122 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 + K F + L+ GQ+Y+ G++L+ ADI ++ + E + S + + Sbjct: 123 SDEDLKRIETAFGFLDTFLE--GQEYVAGDQLTVADIAILSTVSTFEVSE-FDFSKYSNV 179 Query: 182 KAL 184 Sbjct: 180 SRW 182 >3MAK-A nrPDB Length = 209 Score = 76.5 bits (187), Expect = 8e-15, Method: Composition-based stats. Identities = 41/185 (22%), Positives = 67/185 (36%), Gaps = 10/185 (5%) Query: 8 HYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRND--GYLMFQQVPMVEIDGMKL 65 +Y S+ A GVE +K + + + L+ + +P + +G L Sbjct: 5 YYLPGSSPCRSVIMTAKAVGVELNKKLLNL-QAGEHLKPEFLKINPQHTIPTLVDNGFAL 63 Query: 66 VQTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 ++RAI Y+ KY LY K K++A+I+ + + A Sbjct: 64 WESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPA 123 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 K F L+ GQDY G+ L+ ADI LV + E IS + + Sbjct: 124 DPEAFKKIEAAFEFLNTFLE--GQDYAAGDSLTVADIALVATVSTFEVAK-FEISKYANV 180 Query: 182 KALKT 186 Sbjct: 181 NRWYE 185 >4MPF-A nrPDB Length = 266 Score = 76.5 bits (187), Expect = 8e-15, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 78/205 (38%), Gaps = 25/205 (12%) Query: 9 YSNIRGR-------MESIR--WLLAAA-GVEFEEKFIKSAEDLDKLRNDGYLM---FQQV 55 Y G + R ++ A G+ E + + + + ++ +L ++ Sbjct: 19 YFQSMGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVK--GQHKSKEFLQINSLGKL 76 Query: 56 PMVEIDGMKLVQTRAILNYIASKY----NLYGKDIKEKALIDMYIEGIADLGEMILLLPF 111 P ++ L ++ AIL Y++ KY + Y D++ +A + Y+ AD +P Sbjct: 77 PTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPL 136 Query: 112 SQPEEQDAKLALIQEKTKNRYFPAFEKVLK------SHGQDYLVGNKLSRADIHLVELLY 165 + ++ R A ++ L+ + +L G +++ AD+ +E L Sbjct: 137 WVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELM 196 Query: 166 YVEELDSSLISSFPLLKALKTRISN 190 L L P L A + R+ Sbjct: 197 QPVALGYELFEGRPRLAAWRGRVEA 221 >1V2A-A nrPDB Length = 210 Score = 75.3 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 33/188 (17%), Positives = 73/188 (38%), Gaps = 10/188 (5%) Query: 8 HYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQ 67 +YS I +S L G+ K + +++ +P + +G + + Sbjct: 4 YYSLISPPCQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQHTIPTLVDNGHVVWE 63 Query: 68 TRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLP-FSQPEEQDAKLA 122 + AI+ Y+ Y LY KD K +++++ + D+G + + + + + Sbjct: 64 SYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRL--FFDIGTLYKRIIDVIHLVMKKEQPS 121 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182 Q + E+ + + Y + L+ ADI L+ + + L + FP ++ Sbjct: 122 DEQMEKLKGALDLLEQFVTE--RAYAAADHLTVADICLLGTVTALNWLK-HDLEPFPHIR 178 Query: 183 ALKTRISN 190 A R+ Sbjct: 179 AWLERVRA 186 >3M8N-A nrPDB Length = 225 Score = 73.8 bits (180), Expect = 6e-14, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 80/201 (39%), Gaps = 17/201 (8%) Query: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPMVEID 61 KL+ G +R LA + + ++ + R +L QVP++E Sbjct: 4 YKLYSMQRSGNSYKVRLALALLDAPY--RAVEVDILRGESRTPDFLAKNPSGQVPLLETA 61 Query: 62 -GMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIA-----DLGEMILLLPFSQPE 115 G L ++ AIL Y+A +L ++A ++ ++G L + Sbjct: 62 PGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKG- 120 Query: 116 EQDAKLALIQEKTKNRY--FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSS 173 +D + +++ + Y E LK++ DY +L+ ADI L + ++ D Sbjct: 121 GRDLQTHALEDWLERGYAALQVMENHLKTN--DYFAAGQLTIADIALYGYTHVADQCD-F 177 Query: 174 LISSFPLLKALKTRISNLPTV 194 +S+FP + A R+ P Sbjct: 178 DLSTFPAVNAWLRRVEQTPGF 198 >2C3Q-A nrPDB Length = 247 Score = 72.6 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 31/191 (16%), Positives = 68/191 (35%), Gaps = 15/191 (7%) Query: 15 RMESIR--WLLAAA-GVEFEEKFIKSAE-DLDKLRNDGYLMFQQVPMVEIDGMKLVQTRA 70 + R ++ A + FE + + + ++VP ++ L ++ A Sbjct: 17 LSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVA 76 Query: 71 ILNYIASKYNL----YGKDIKEKALIDMYIE-GIADLGEMILLLPFSQ---PEEQDAKLA 122 IL Y+ KY + Y +D++ +A +D Y+ L L + + P ++ Sbjct: 77 ILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVS 136 Query: 123 LIQEKTKNRYFPAFEKVLKS---HGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP 179 ++L+ + +L G +S AD+ + L + + P Sbjct: 137 PQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRP 196 Query: 180 LLKALKTRISN 190 L + R+ Sbjct: 197 KLATWRQRVEA 207 >4PXO-A nrPDB Length = 238 Score = 72.2 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 38/213 (17%), Positives = 67/213 (31%), Gaps = 20/213 (9%) Query: 9 YSNIRGRME-SIRWLLAAAGVEFEEKFIK-SAEDLDKLRNDGYLMFQQVPMVEI-DGMKL 65 Y N R +R L G+ +EE F+ A D K VP + DG L Sbjct: 27 YGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALFDGDGPPL 86 Query: 66 VQTRAILNYIASKYNLYGKDIKE---------KALIDMYIEGIADLGEMILLLPFSQPEE 116 Q+ AIL+Y+ +E A + + + + Sbjct: 87 TQSLAILDYLEETRTGVPLLPEEPRARARARSLAQV-VACDTHPLYVPRVRTFLMENYGL 145 Query: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYVEELDSSL 174 ++ E L + + G+ +S AD+ L+ L Sbjct: 146 PRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLWVGTGIFGID- 204 Query: 175 ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 +++P +K + + L V + P + P Sbjct: 205 TAAYPTVKRISEEVLALDAVAR----AHPLRQP 233 >3PR8-A nrPDB Length = 229 Score = 71.5 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 44/223 (19%), Positives = 85/223 (38%), Gaps = 15/223 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKL 65 KL+ ++ ++ L G+ FEE + L +VP++E + L Sbjct: 4 KLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQALEVS---PRGKVPVLETEHGFL 60 Query: 66 VQTRAILNYIASKYN---LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLA 122 +T IL+YI L D +A + ++ I E+ +++ + Sbjct: 61 SETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVEP 120 Query: 123 LIQEKTKNRYFPAFEKVLKSHGQ--DYLVGNKLSRADIHLVELLYYVE-----ELDSSLI 175 LI+EK + F LK +G+ Y+ G +L+ AD+ + L+ + Sbjct: 121 LIKEKARADLLAGF-ATLKRNGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNIDFL 179 Query: 176 SSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 + FP KAL + P + + L P + + ++ Sbjct: 180 ADFPQAKALLQLMGENPHMPRILA-DKEASMPAFMEMIRSGKR 221 >3GH6-A nrPDB Length = 210 Score = 71.1 bits (173), Expect = 4e-13, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 64/186 (34%), Gaps = 9/186 (4%) Query: 7 LHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRND--GYLMFQQVPMVEIDGMK 64 L+Y S+ A GVEF++K I + ++ + +P + G Sbjct: 3 LYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFA 62 Query: 65 LVQTRAILNYIASKYN----LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 L ++RAI+ Y+ KY L+ KD++++ALI+ + + Sbjct: 63 LWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFLKKP 122 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 K F L+ GQ Y G S ADI + + + + Sbjct: 123 ANEENYKKIEVAFEFLNTFLE--GQTYSAGGDYSLADIAFLATVSTFDV-AGFDFKRYAN 179 Query: 181 LKALKT 186 + Sbjct: 180 VARWYE 185 >3IBH-A nrPDB Length = 233 Score = 69.9 bits (170), Expect = 9e-13, Method: Composition-based stats. Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 18/202 (8%) Query: 18 SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM---FQQVPMVE-IDGMKLVQTRAILN 73 +R LA + +F++ + + +L VP++E DG + + AI Sbjct: 32 RVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITE 91 Query: 74 YIASKYN---LYGKDIKEKALIDMYIEGIA-DLGEMILLL-----PFSQPEEQDAKLALI 124 YI + L GK EK +I M + +L + + + P PE + + Sbjct: 92 YIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEW 151 Query: 125 QEKTKNRYFP---AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLL 181 + +++ F+ VL+ + Y+ G+ S ADI ++ L + + + L Sbjct: 152 GLRQRDKALHGMHYFDTVLRE--RPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEAL 209 Query: 182 KALKTRISNLPTVKKFLQPGSP 203 +A R+ P+VKK L+ S Sbjct: 210 RAWYKRMQQRPSVKKLLEIRSK 231 >3UBL-A nrPDB Length = 242 Score = 67.2 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 38/191 (19%), Positives = 82/191 (42%), Gaps = 16/191 (8%) Query: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMK 64 KLH ++I + ++ + G+E+E+ I +++ D L+ ++P++E+DG Sbjct: 4 IKLHGASISNYVNKVKLGILEKGLEYEQIRIAPSQEEDFLKIS---PMGKIPVLEMDGKF 60 Query: 65 LVQTRAILNYIASKY----NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK 120 + ++ AIL ++ + + L +D E A + I ++ + + + Sbjct: 61 IFESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPE 120 Query: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRAD---IHLVELLYYVEELDSSLISS 177 + T + A ++V++ Y+ GN + AD + +L EEL ++ Sbjct: 121 IVEEVHSTLVKGIKALQRVVRFS--PYIAGNVFTLADCSGFAHLSVLD--EELRPFYPNN 176 Query: 178 FP--LLKALKT 186 P LL K Sbjct: 177 HPLDLLNGWKE 187 >3LFL-A nrPDB Length = 240 Score = 66.4 bits (161), Expect = 8e-12, Method: Composition-based stats. Identities = 38/192 (19%), Positives = 70/192 (36%), Gaps = 12/192 (6%) Query: 16 MESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEID-GMKLVQTRAILNY 74 E R +L A G+ E I + F VP++E G + ++ Y Sbjct: 35 AERTRLVLKAKGIRHEVININLKNKPEWFFKKN--PFGLVPVLENSQGQLIYESAITCEY 92 Query: 75 IASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNR 131 + Y L D EKA M +E + + ++ F + + ++ A ++E+ + Sbjct: 93 LDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVG--SFIRSQNKEDY-AGLKEEFRKE 149 Query: 132 YFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS-SLISSFPLLKALKTRISN 190 + +VL + + GN +S D + +E + + P LK + Sbjct: 150 FTKL--EVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKE 207 Query: 191 LPTVKKFLQPGS 202 PTV L Sbjct: 208 DPTVSALLTSEK 219 >2PMT-A nrPDB Length = 203 Score = 65.3 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 42/202 (20%), Positives = 80/202 (39%), Gaps = 25/202 (12%) Query: 6 KLHYSNIRGRME-SIRWLLAAAGVEFEEKFI-------KSAEDLDKLRNDGYLMFQQVPM 57 KL+Y+ G S +L G++F + I +S +D + QVP+ Sbjct: 2 KLYYTP--GSCSLSPHIVLRETGLDFSIERIDLRTKKTESGKDFLAINPK-----GQVPV 54 Query: 58 VEID-GMKLVQTRAILNYIAS---KYNL-YGKDIKEKALIDMYIEGIADLGEMILLLPFS 112 +++D G L + AI+ Y+A NL E+ ++ +A P Sbjct: 55 LQLDNGDILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYS-PLF 113 Query: 113 QPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS 172 + ++ L +++ K K+++ VL Q + G+ + AD +L L + Sbjct: 114 SSDTPESYLPVVKNKLKSKFV-YINDVLSK--QKCVCGDHFTVADAYLF-TLSQWAPHVA 169 Query: 173 SLISSFPLLKALKTRISNLPTV 194 ++ L+ RI+ P V Sbjct: 170 LDLTDLSHLQDYLARIAQRPNV 191 >3TOT-A nrPDB Length = 226 Score = 65.3 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 37/187 (19%), Positives = 67/187 (35%), Gaps = 16/187 (8%) Query: 19 IRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMV-EIDGMKLVQTRAILNYIAS 77 +R +LA +++ +F+ + + +VP + DG L +R I Y A Sbjct: 17 VRVVLAEKKIDY--QFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALFDSRVIAEY-AD 73 Query: 78 KY----NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQ----PEEQDAKLALIQEKTK 129 L +E+ + + L + + L Q PE++ Q Sbjct: 74 TLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRSESWITRQHHKI 133 Query: 130 NRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL--ISSFPLLKALKTR 187 + A + L + + GN L+ ADI + L Y++ + L A TR Sbjct: 134 DEALKAMSRGLAD--RTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQHANLAAFYTR 191 Query: 188 ISNLPTV 194 I P+ Sbjct: 192 IEKRPSF 198 >2PVQ-A nrPDB Length = 201 Score = 64.1 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 40/201 (19%), Positives = 79/201 (39%), Gaps = 13/201 (6%) Query: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGY--LMFQQVPMVEID-G 62 KL+Y + +L+ AG+ +E + + D + VP +E+ G Sbjct: 2 KLYYKVGAASLAP-HIILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKPG 60 Query: 63 MKLVQTRAILNYIASKYNLYGKDIK----EKALIDMYIEGIADLGEMILLLPFSQPEEQD 118 + Q AIL YI ++ E+A + + +DL L F+ ++ Sbjct: 61 TVITQNAAILQYIGDHSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGL-FAPNLSEE 119 Query: 119 AKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 A+ +I NR E +L +L G+ ++ D + ++ + +S++ Sbjct: 120 ARAGVIAN--INRRLGQLEAMLSDKNAYWL-GDDFTQPDAYASVIIGW-GVGQKLDLSAY 175 Query: 179 PLLKALKTRISNLPTVKKFLQ 199 P L+ R+ P V+K + Sbjct: 176 PKALKLRERVLARPNVQKAFK 196 >5ELG-A nrPDB Length = 221 Score = 64.1 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 36/205 (17%), Positives = 75/205 (36%), Gaps = 33/205 (16%) Query: 17 ESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPMVEIDGMKLVQTRAILN 73 + L + ++ I ++ + +L +VP+++ID + + I+ Sbjct: 24 QRALLTLEEKSLTYKIHLINLSD-----KPQWFLDISPQGKVPVLKIDDKWVTDSDVIVG 78 Query: 74 YIASKYNLYG-KDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRY 132 + KY K E A + +++ S+ ++ AL+ E Sbjct: 79 ILEEKYPDPPLKTPAEFASVG------SNIFGTFGTFLKSKDSNDGSEHALLVE------ 126 Query: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLP 192 A E LKSH ++ G ++S D+ L LY+++ S + + P Sbjct: 127 LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKS--------WSVPESFP 178 Query: 193 TVKKFLQP----GSPRKPPMDEKSL 213 V +++ S K +EK + Sbjct: 179 HVHNYMKTLFSLDSFEKTKTEEKYV 203 >4J2F-A nrPDB Length = 223 Score = 63.4 bits (153), Expect = 7e-11, Method: Composition-based stats. Identities = 46/210 (21%), Positives = 78/210 (37%), Gaps = 24/210 (11%) Query: 1 MAEKPKLH-YSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQ----QV 55 MAE KLH I W L G+ +E EDL ++ L + ++ Sbjct: 1 MAEVLKLHGAWPSPFSCRVI-WALKLKGIPYE----YVEEDLFN-KSPLLLQYNPVHKKI 54 Query: 56 PMVEIDGMKLVQTRAILNYIASK---YNLYGKDIKEKALIDMYIEGIADLGEMILLLPFS 112 P++ G + ++ IL Y+ L D E+A+ +++ I D G I + + Sbjct: 55 PVLVHGGKPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRT 114 Query: 113 QPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADI------HLVELLYY 166 + EE + + E K E + Y G+K+ DI H + ++ Sbjct: 115 KGEELEKAVKNCLEVLKTIE----EHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEE 170 Query: 167 VEELDSSLISSFPLLKALKTRISNLPTVKK 196 V + FP L A P +K+ Sbjct: 171 VAGVKVLESQKFPRLHAWTENFKEAPIIKE 200 >5LOL-A nrPDB Length = 215 Score = 63.4 bits (153), Expect = 8e-11, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 64/163 (39%), Gaps = 25/163 (15%) Query: 17 ESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPMVEIDGMKLVQTRAILN 73 + + L + ++ I ++ + +L +VP+V++DG + + I+ Sbjct: 26 QRVLLTLEEKKLPYKTHLINVSD-----KPQWFLDISPEGKVPVVKLDGKWVADSDVIVG 80 Query: 74 YIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKN 130 + KY +L K E A + I G + F + ++ + EK Sbjct: 81 LLEEKYPEPSL--KTPPEFASVGSKIFG--------AFVTFLKSKDANDGS----EKALV 126 Query: 131 RYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSS 173 A E LK+H ++ G K++ D+ L LY++E Sbjct: 127 DELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGH 169 >3LG6-A nrPDB Length = 235 Score = 63.0 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 33/209 (15%), Positives = 70/209 (33%), Gaps = 22/209 (10%) Query: 9 YSNIRGRME-SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL-MFQQVPMVEID----- 61 Y R +R + + + + L VP++ + Sbjct: 13 YGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNINNT 72 Query: 62 ------GMKLVQTRAILNYIASK-----YNLYG--KDIKEKALIDMYIEGIADLGEMILL 108 + Q+ A L Y+ L + +A + IA + + Sbjct: 73 VSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIACDVQPVTN 132 Query: 109 LPFSQPEEQ-DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYV 167 L + + D + + F A EK+L+ + VG++++ AD+ LV ++ Sbjct: 133 LKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAA 192 Query: 168 EELDSSLISSFPLLKALKTRISNLPTVKK 196 E + ++ FP+ K + + V+K Sbjct: 193 ERV-GMDLARFPITKRVFEEMLKEEAVQK 220 >3NIV-A nrPDB Length = 222 Score = 62.6 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 79/200 (39%), Gaps = 15/200 (7%) Query: 9 YSNIRG-RMESIRWLLAAAGVEFE---EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMK 64 Y R +R L + +E + + + L+ + VP ++I+G Sbjct: 6 YDYFRSTACYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDINGQI 65 Query: 65 LVQTRAILNYIASKY---NLYGKDI-KEKALIDMYIEGIADLGEMILLLPFSQPEEQ--- 117 L Q+ AI++Y+ + L KD + L M + D+ + L ++ +EQ Sbjct: 66 LSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKEQFNA 125 Query: 118 -DAKLALIQEKTKNRYFPAFEKVLKS--HGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 + ++ F AFE+ L + + G+++ AD+ L+ +Y Sbjct: 126 NEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHRFH-FD 184 Query: 175 ISSFPLLKALKTRISNLPTV 194 ++S+P++ + LP Sbjct: 185 MASYPIINEINEYCLTLPAF 204 >4QQ7-A nrPDB Length = 207 Score = 62.2 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 31/191 (16%), Positives = 75/191 (39%), Gaps = 12/191 (6%) Query: 17 ESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIA 76 + R +L G++FE + + + + + QVP++ + L ++ I YI Sbjct: 18 QRCRLVLFEKGMDFEIRDVDLFNKPEDI--SVMNPYGQVPILVERDLILYESNIINEYID 75 Query: 77 SKYN---LYGKDIKEKALIDM-YIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRY 132 ++ L D ++A + + +L + L + + + + ++R Sbjct: 76 ERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAEKNHEKARLAIRDRL 135 Query: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLP 192 +K+ Y++G + S D+ + LL+ ++ L + L RI + P Sbjct: 136 TQLAPIFVKN---KYMLGEEFSMLDVAIAPLLWRLDHYGIELSKNAAPLMKYAERIFSRP 192 Query: 193 TVKKFLQPGSP 203 +++ +P Sbjct: 193 ---AYIEALTP 200 >2JL4-A nrPDB Length = 213 Score = 59.5 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 70/206 (33%), Gaps = 18/206 (8%) Query: 4 KPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSA-EDLDKLRNDGYLMFQQVPMVEIDG 62 K KL+ G +R L GV +E + E+ K Q VP ++ Sbjct: 1 KMKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGA 60 Query: 63 MKLVQTRAILNYIASKYN---LYGKDIKEKALIDMYIEGIA-DLGE-------MILLLPF 111 L+Q+ AI+ ++ +Y L D + + + D+ L F Sbjct: 61 QVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRKTF 120 Query: 112 SQPEEQDAKLALIQEKTKNRYFPAFEKVLKSH--GQDYLVGNKLSRADIHLVELLYYVEE 169 E + F A+E +L Y G+ + AD +LV + Sbjct: 121 GADEAAINAWC---GTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESARR 177 Query: 170 LDSSLISSFPLLKALKTRISNLPTVK 195 ++ +PL++A+ L + Sbjct: 178 FQVD-LTPYPLIRAVDAACGELDAFR 202 >4CHS-A nrPDB Length = 219 Score = 59.1 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 31/189 (16%), Positives = 72/189 (38%), Gaps = 19/189 (10%) Query: 18 SIRWLLAAAGVEFE--EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 +R LA G+E+E E+ +++ L N + +++P++ +G + ++ + YI Sbjct: 18 RVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVH---KKIPVLIHNGKPISESLIAVQYI 74 Query: 76 A----SKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNR 131 + L D ++A + + + + ++ E+ +K Sbjct: 75 EEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEEKE----AAKKEFIE 130 Query: 132 YFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS----SLISSFPLLKALKTR 187 E+ L + Y G+ + DI LV + + ++ ++ + P A R Sbjct: 131 ALKLLEEQLGD--KTYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENECPRFVAWAKR 188 Query: 188 ISNLPTVKK 196 +V K Sbjct: 189 CLQKESVAK 197 >4MK3-A nrPDB Length = 226 Score = 58.4 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 61/187 (32%), Gaps = 16/187 (8%) Query: 16 MESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMV-EIDGMKLVQTRAILNY 74 +R +LA +++E I+ + +VP + DG + +R I Y Sbjct: 34 ARKVRVVLAEKKIDYE--MIEENVWSPDTTIGRFNPLGKVPCLVMEDGGAVFDSRVIAEY 91 Query: 75 IASKY----NLYGKDIKEKALIDMYIEGIADLGEMILLLPFS----QPEEQDAKLALIQE 126 A L + +E+ + + L + LL + E+ Q Sbjct: 92 -ADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKESERSESWVQRQR 150 Query: 127 KTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI--SSFPLLKAL 184 + A L + + G + AD+ + L Y++ + P L A Sbjct: 151 SKIDAALTAMSTGLAD--KTWCTGTHYTLADVAVGCALAYLDFRFPDIAWRDRHPNLVAF 208 Query: 185 KTRISNL 191 + +I Sbjct: 209 QEKIEKR 215 >3GX0-A nrPDB Length = 215 Score = 58.4 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 68/200 (34%), Gaps = 21/200 (10%) Query: 9 YSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPMVEI----D 61 Y I L A +++ + IK +L ++P + D Sbjct: 5 YFAPTPNGHKITLFLEEAELDY--RLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSPAD 62 Query: 62 G---MKLVQTRAILNYIASKYNLYGKDI-KEKALIDMY----IEGIADLGEMILLLPFSQ 113 G + L ++ AIL Y+A K L+ +E+A + + G+ + + Sbjct: 63 GGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAA 122 Query: 114 PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSS 173 P + + R + K L++ +L G S ADI + Sbjct: 123 P-QTIPYAIERYQVETQRLYHVLNKRLENS--PWLGGENYSIADIACWPWVNAWTRQRID 179 Query: 174 LISSFPLLKALKTRISNLPT 193 ++ +P +K RI + P Sbjct: 180 -LAMYPAVKNWHERIRSRPA 198 >4IKH-A nrPDB Length = 244 Score = 57.6 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 75/192 (39%), Gaps = 21/192 (10%) Query: 21 WLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQ--VPMV------EIDGMKLVQTRAIL 72 +L G+ +E + S E D++ + + +P + + L ++ AIL Sbjct: 38 IMLEEIGLPYEAHRV-SFETQDQMTPEFLSVSPNNKIPAILDPHGPGDQPLALFESGAIL 96 Query: 73 NYIASKYN-LYGKDIKEKALIDMYIE-GIADLGEMILLLPFSQP----EEQDAKLALIQE 126 Y+A K L ++ + ++ + +G M + F E +D + Sbjct: 97 IYLADKSGQLLAQESAARYETIQWLMFQMGGIGPMFGQVGFFNKFAGREYEDKRPLERYV 156 Query: 127 KTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLV----ELLYYVEELDSSLISSFPLLK 182 R +K L G+++++G + + ADI L+ + E + I +FP +K Sbjct: 157 NEAKRLLGVLDKHLG--GREWIMGERYTIADIATFPWIRNLIGFYEAGELVGIDNFPEVK 214 Query: 183 ALKTRISNLPTV 194 + + P V Sbjct: 215 RVLAKFVARPAV 226 >4MDC-A nrPDB Length = 252 Score = 57.6 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 35/217 (16%), Positives = 72/217 (33%), Gaps = 37/217 (17%) Query: 19 IRWLLAAAGVEFE---EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMK----------- 64 +R +L+ G + E E+ ++ D L +P+ D M+ Sbjct: 38 VRLILSEYGYQTELSEEQPWENRRDFLTLNPA-----GTLPVYVDDSMRALCGATIISEY 92 Query: 65 LVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPF---------SQPE 115 L +T I+ L +D ++A I E E + P P+ Sbjct: 93 LDETSGIMK---RDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRERIFKLQMTPD 149 Query: 116 EQ----DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELD 171 + D+K+ ++ + + +L G+++S D+ + ++ L Sbjct: 150 QGGGAPDSKILRTSRSNIRQHMKYLS--WLAGSRPWLAGDRISYGDLAAAAAISVLDYLG 207 Query: 172 SSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPM 208 S P K R+ + P+ + L P+ Sbjct: 208 EIDWSDAPTAKEWYQRLKSRPSFRPLLAERVRGVTPV 244 >2VO4-A nrPDB Length = 219 Score = 57.6 bits (138), Expect = 5e-09, Method: Composition-based stats. Identities = 32/189 (16%), Positives = 72/189 (38%), Gaps = 19/189 (10%) Query: 18 SIRWLLAAAGVEFE--EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 +R LA G+++E E+ +++ L N + +++P++ +G + ++ + YI Sbjct: 18 RVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVH---KKIPVLIHNGKPICESLIAVQYI 74 Query: 76 A----SKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNR 131 + L D ++A + + + + ++ E+ +K Sbjct: 75 EEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKE----AAKKEFIE 130 Query: 132 YFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS----SLISSFPLLKALKTR 187 E+ L + Y G+ L DI LV + + ++ ++ S P A R Sbjct: 131 ALKLLEEQLGD--KTYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIESECPKFIAWAKR 188 Query: 188 ISNLPTVKK 196 +V K Sbjct: 189 CLQKESVAK 197 >5J5N-A nrPDB Length = 231 Score = 57.2 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 71/198 (35%), Gaps = 23/198 (11%) Query: 18 SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQ----QVPMVEIDGMKLVQTRAILN 73 +R LA GV++E S EDL ++ L Q+P++ +G + ++ I+ Sbjct: 30 RVRLALAEKGVKYE----YSEEDL-WNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQ 84 Query: 74 YI----ASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTK 129 YI L D ++A + + + + +++ E+ +K Sbjct: 85 YIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQE----AAKKDF 140 Query: 130 NRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS----SLISSFPLLKALK 185 E L + Y G + DI LV + ++ ++ + P + A Sbjct: 141 IDSLKLMEGELGD--KPYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKMIAYC 198 Query: 186 TRISNLPTVKKFLQPGSP 203 R TV K L+ Sbjct: 199 KRCLQKETVSKALEDPQK 216 >3C8E-A nrPDB Length = 288 Score = 57.2 bits (137), Expect = 6e-09, Method: Composition-based stats. Identities = 28/194 (14%), Positives = 64/194 (32%), Gaps = 25/194 (12%) Query: 21 WLLAAAGVEFEE--KFIKSAEDLDKLRNDGYLMFQQVPMVEIDGM----KLVQTRAILNY 74 L G E++ I + + ++P + ++ ++ +IL Y Sbjct: 66 LALGVTGAEYDAWLIRIGDGDQFSSGFVE-VNPNSKIPALRDHTHNPPIRVFESGSILLY 124 Query: 75 IASKYN-LYGKDIKEKALID---MYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKN 130 +A K+ +D+ ++ +++G A + + Sbjct: 125 LAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFTMEAK 184 Query: 131 RYFPAFEKVLKSHGQDYLVGNKLSRAD---------IHLVELLYYVEELDSSLISSFPLL 181 R +K L H ++ G++ + AD + L + E LD+ S+ + Sbjct: 185 RLLDVLDKQLAQH--KFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAG---SYKHV 239 Query: 182 KALKTRISNLPTVK 195 + + P VK Sbjct: 240 QRWAKEVGERPAVK 253 >5F8B-A nrPDB Length = 244 Score = 55.7 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 21/122 (17%) Query: 52 FQQVPMVE-IDGMKLVQTRAILNYIASKYN---LYGKDIKEKALI---------DMYIEG 98 +VP + D KL + AI YI S+ L GKD KE A I ++ I Sbjct: 47 LGKVPAFQGADSFKLFECMAIALYITSQNEQTTLLGKDKKEYAEIIKWMSFFNTEIVILM 106 Query: 99 IADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADI 158 L + ++P+ + + R E+ L+ + +LVG++LS AD+ Sbjct: 107 TQQLLPQLGVIPYDRDQ------VEFFANMTQRSVDVVEEYLQD--RTFLVGDQLSLADL 158 Query: 159 HL 160 Sbjct: 159 FC 160 >5N9U-A nrPDB Length = 218 Score = 55.7 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 61/187 (32%), Gaps = 21/187 (11%) Query: 16 MESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 + + L + ++ I D + + +VP+V+ID + + I+ + Sbjct: 23 CQRVLLSLEEKKIPYKSHLINLG-DKPQWFLEIS-PEGKVPVVKIDDKWVADSDVIVGIL 80 Query: 76 ASKYNLYG-KDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFP 134 K E A + G + L P + E+ Sbjct: 81 EEKNPEPPLATPPEFASV-----GSKIFPSFVKFLKSKDPNDGT-------EQALLEELK 128 Query: 135 AFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI-----SSFPLLKALKTRIS 189 A + LK HG ++ G K++ D+ L LY++E + + + Sbjct: 129 ALDGHLKVHG-PFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHVLNYIKLLF 187 Query: 190 NLPTVKK 196 + + KK Sbjct: 188 SRESFKK 194 >5NR1-A nrPDB Length = 228 Score = 54.5 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 41/224 (18%), Positives = 77/224 (34%), Gaps = 22/224 (9%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 M+ + LH+ + +R L + F E ++ E + P++ Sbjct: 1 MSVERTLHHFPLDPASRQVRLALGEKRLPFVEMQVRYWEMPPEF--TSLNPSGMPPVLVE 58 Query: 61 DGMK----LVQTRAILNYIASKY---NLYGKDIKEKALID---MYIEGIAD-------LG 103 + + +TRAIL +I L G+D E+A + + D L Sbjct: 59 TKHQRNLVICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFLLH 118 Query: 104 EMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVEL 163 E + A L +E + + E +L++ +D+L G ++S AD Sbjct: 119 EKMEKRLLRMGAPDLAALRQGREALRM-HLGYIESLLQT--RDWLAGRRMSLADFAAAAH 175 Query: 164 LYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 L ++ F K ++ + P + L P P Sbjct: 176 LSVIDYFGDVPWKDFQAAKTWYMKLKSRPCFRPILADRWPGLAP 219 >5G5A-A nrPDB Length = 221 Score = 54.5 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 67/204 (32%), Gaps = 15/204 (7%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 MA++ L R L V+F + + + + + + +++P++ Sbjct: 1 MADEVILLDFWPSMFGMRTRIALEEKNVKF-DYREQDLWNKSPILLEMNPVHKKIPVLIH 59 Query: 61 DGMKLVQTRAILNYIAS----KYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEE 116 +G + ++ + YI K L D ++A + + I L + E Sbjct: 60 NGNPVCESLIQIEYIDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGE 119 Query: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS---- 172 + +K E L + Y G DI L+ + E + Sbjct: 120 EHE----AGKKEFIEILKTLESELGD--KTYFGGETFGYVDIALIGFYSWFEAYEKFGSF 173 Query: 173 SLISSFPLLKALKTRISNLPTVKK 196 S+ + P L A R +V K Sbjct: 174 SIEAECPKLIAWGKRCVERESVAK 197 >5ECL-B nrPDB Length = 223 Score = 53.3 bits (127), Expect = 9e-08, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 65/208 (31%), Gaps = 23/208 (11%) Query: 1 MAEKPKLH-YSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQ---QVP 56 MA P L Y R L GVEFE ED ++P Sbjct: 7 MANLPILLDYWPSM-FGMRARVALREKGVEFE----YREEDFSNKSPLLLQSNPIHKKIP 61 Query: 57 MVEIDGMKLVQTRAILNYI----ASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFS 112 ++ +G + ++ ++ Y+ K + D +A + + + + Sbjct: 62 VLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWG 121 Query: 113 QPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDS 172 + E+ +K E L + Y G+ DI L+ + + + Sbjct: 122 KKGEEQE----AGKKEFIEAVKILESELGD--KPYFGGDSFGYVDISLITFSSWFQAYEK 175 Query: 173 ----SLISSFPLLKALKTRISNLPTVKK 196 S+ S P L A R +V K Sbjct: 176 FGNFSIESESPKLIAWAKRCMEKESVSK 203 >3RBT-A nrPDB Length = 246 Score = 51.0 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 41/205 (20%), Positives = 78/205 (38%), Gaps = 28/205 (13%) Query: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIK--SAEDLDKLRNDGYLMFQQVPMV 58 + +K +L++ ++ + +L A +++E + + + +N ++P++ Sbjct: 23 LTDKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRL----KIPVL 78 Query: 59 EI----DGMKLVQTRAILNYIASK---YNLYGKDIKEKALIDMYIEGIADLGEMILLLPF 111 EI L ++ I +Y+ K + L+ D KA + IE +L + L Sbjct: 79 EIPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSL---- 134 Query: 112 SQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIH---LVELLYYVE 168 E D A E+ FEK L + G +Y GN+ D VE LY + Sbjct: 135 ---ECFDTNFAFGSEQIIQT-LEIFEKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLR 190 Query: 169 -ELDSSLISS---FPLLKALKTRIS 189 D + FP ++ Sbjct: 191 CVNDRKFVEKKSLFPNFADWGDQMQ 215 >1N2A-A nrPDB Length = 201 Score = 49.5 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 65/181 (35%), Gaps = 15/181 (8%) Query: 23 LAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLV-QTRAILNYIASKYN- 80 V+ +K +++ +D + QVP + +D L+ + AI+ Y+A Sbjct: 25 FTLVSVDLMKKRLENGDDYFAVNPK-----GQVPALLLDDGTLLTEGVAIMQYLADSVPD 79 Query: 81 ---LYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFE 137 L + + ++ IA F ++ K + + K Sbjct: 80 RQLLAPVNSISRYKTIEWLNYIATELHKGFTPLFRPDTPEEYKPTVRAQLEKK--LQYVN 137 Query: 138 KVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKF 197 + LK + ++ G + + AD +L +L + + + A R++ P V+ Sbjct: 138 EALKD--EHWICGQRFTIADAYLFTVLRWA-YAVKLNLEGLEHIAAFMQRMAERPEVQDA 194 Query: 198 L 198 L Sbjct: 195 L 195 >4BVY-B nrPDB Length = 186 Score = 49.1 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 30/162 (18%), Positives = 57/162 (35%), Gaps = 34/162 (20%) Query: 54 QVPMVEI-DGMKLVQTRAILNYIASKYN---LYGKDIKEKALIDMYIEGIADLGEMILLL 109 Q+P+++ DG L I ++ + N L G +EKA++ ++E Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLE------------ 88 Query: 110 PFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQD--YLVGNKLSRADIHLVELLYYV 167 ++ + + K L S+ +D YL G + ADI L Y + Sbjct: 89 ---------YRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLY---YGL 136 Query: 168 EELDSSLI----SSFPLLKALKTRISNLPTVKKFLQPGSPRK 205 L + + + I + P +++ L K Sbjct: 137 HRFIVDLTVQEKEKYLNVSRWFSHIQHYPGIRQHLSSVVFIK 178 >3PPU-A nrPDB Length = 352 Score = 48.7 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 44/119 (36%), Gaps = 15/119 (12%) Query: 78 KYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFE 137 K +LY + + +A ID + + D + K E Sbjct: 195 KLDLYPESL--RAKIDEVNDWVYDTVN---NGVYKSGFASTQKAYEAAVIPLFESLDRLE 249 Query: 138 KVLKSHGQDYLVGNKLSRADIHLVELL-----YYVEELDSSL---ISSFPLLKALKTRI 188 K+L+ GQDYL+G +L+ ADI L + YV +L +P L ++ Sbjct: 250 KMLE--GQDYLIGGQLTEADIRLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWMRKL 306 >4PQI-A nrPDB Length = 241 Score = 48.0 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 25/163 (15%), Positives = 52/163 (31%), Gaps = 20/163 (12%) Query: 42 DKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALIDMYIEG 98 + +VP +E +G ++ ++ Y+ S + +L KD +K + Sbjct: 71 PAWYPEKVYPPNKVPSLEHNGKITGESLDLIKYLESNFEGPSLLPKDPAKKEFAEELFSY 130 Query: 99 IADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVL-KSHGQDYLVGNKLSRAD 157 + F ++A A F E L K + +G + S D Sbjct: 131 TDKFNGTVYT-AFKGDLAKEAGPA----------FDHLENALHKFDDGPFFLGKEFSLVD 179 Query: 158 IHLVELLY-----YVEELDSSLISSFPLLKALKTRISNLPTVK 195 I + + +E + + L A ++ + K Sbjct: 180 IAYIPFVERLNIFLLEVFKYDITAGRQKLAAWIEEVNKIEAYK 222 >4FQU-A nrPDB Length = 313 Score = 46.4 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 56/152 (36%), Gaps = 20/152 (13%) Query: 67 QTRAILNYIASKY---NLYGKD--IKE-KALIDMYIEGIAD-LGEMILLLPFSQPEEQDA 119 ++ I+ + S + D E + ID + + L + F+ +E Sbjct: 137 ESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYE 196 Query: 120 KLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLY-----YVEELDSSL 174 + E+ L G+++LVG++L+ ADI L L Y +L Sbjct: 197 EAFY----PLFDTLDWLEEHL--TGREWLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNL 250 Query: 175 --ISSFPLLKALKTRISNLPTVKKFLQPGSPR 204 I+ +P L L ++++ V + + Sbjct: 251 RRIADYPNLSRLVGKLASHERVAPTINLRHAK 282 >4AGS-A nrPDB Length = 471 Score = 46.4 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 22/156 (14%), Positives = 48/156 (30%), Gaps = 13/156 (8%) Query: 16 MESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI---DGMKLVQTRAIL 72 + + V ++ + E++ + + VP +E+ D + ++ I Sbjct: 38 CHRVEIVAREKQVSYDRVAVGLREEMPQWY-KQINPRETVPTLEVGNADKRFMFESMLIA 96 Query: 73 NYI----ASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKT 128 Y+ A L G ++ I+ ++ + D L + K Sbjct: 97 QYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGLLRDPLSGEKRKAMDDNAAY 156 Query: 129 KNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELL 164 + A Y + + AD+ LV L Sbjct: 157 VDGLLAA-----NQTTGPYYCDGEFTMADVALVPFL 187 >6JWK-A nrPDB Length = 222 Score = 46.0 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 37/207 (17%), Positives = 71/207 (34%), Gaps = 28/207 (13%) Query: 18 SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL--MFQQVPMVEI-DGMKLVQTRAILNY 74 +R LA G++++ + ++LR +P + DG + Q+ AI++Y Sbjct: 14 RVRIALALKGLDYQVVPVNLR-QGEQLRPADRQRNPMGALPTLVDADGRRFSQSLAIIDY 72 Query: 75 IAS---KYNLYGKDIKEKALIDMY----------IEGIADLGEMILLLPFSQPEEQDAKL 121 + + + L D +A + + L + +L + Q Sbjct: 73 LDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVLGIDAEDRQRWYA 132 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQ-DYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + E A E +L H + + G + LV L + ++ +P Sbjct: 133 HWVAE-----GLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANARRMGCD-LAPYPA 186 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPP 207 L L+ R L Q SP + P Sbjct: 187 LLELEGRCLALEAF----QRASPERQP 209 >6GC9-A nrPDB Length = 327 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 45/122 (36%), Gaps = 14/122 (11%) Query: 80 NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKV 139 +LY + + + ID E + D + K EK+ Sbjct: 168 DLYPEAL--RGEIDGINEWVYDTVN---NGVYKSGFATSQKAYEAAVVPLFESLDRLEKI 222 Query: 140 LKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP-LLKALKTRISNLPTVKKFL 198 L G+DYLVG++L+ ADI L + D + F ++ ++ P + ++ Sbjct: 223 L--TGKDYLVGDQLTEADIRLFVTIV---RFDPVYVGHFKCNIRTIRD---GYPAIDLWM 274 Query: 199 QP 200 + Sbjct: 275 RK 276 >1G6W-A nrPDB Length = 261 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 32/190 (16%), Positives = 71/190 (37%), Gaps = 45/190 (23%) Query: 54 QVPMVEI---DGMKLVQTRAILNYIASKYN-------LYGKDIKEKALIDMYI----EGI 99 +VP + D + + ++ AIL ++ +KY L+ D+ +++ I+ ++ G Sbjct: 71 RVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGH 130 Query: 100 ADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQD------------- 146 A + L + ++ + + ++ + R + E L + Sbjct: 131 APMIGQALHFRYFHSQKIASAVERYTDEVR-RVYGVVEMALAERREALVMELDTENAAAY 189 Query: 147 -----------------YLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRIS 189 +LVG+KL+ AD+ V V+ + ++ FP + + Sbjct: 190 SAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMM 249 Query: 190 NLPTVKKFLQ 199 P V K L+ Sbjct: 250 RRPAVIKALR 259 >5IQY-A nrPDB Length = 216 Score = 44.9 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 58/165 (35%), Gaps = 27/165 (16%) Query: 17 ESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL---MFQQVPMVEI-DGMKLVQTRAIL 72 + + L + +E K + + + + +L +VP+ DG + + I Sbjct: 27 QRVLLTLEEKKITYEMKLVDLSN-----KPEWFLKISPEGKVPVFNSGDGKWIADSDVIT 81 Query: 73 NYIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTK 129 I K+ +L E A + + P + + EK Sbjct: 82 QVIEEKFPTPSLV--TPPEYASV------------GSKIFPSFVKFLKSKDASDGSEKAL 127 Query: 130 NRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 A ++ LK+HG Y+ G +S AD+ L L++++ Sbjct: 128 LDELQALDEHLKAHG-PYISGENVSAADLSLGPKLFHLQVALEHF 171 >6GCB-A nrPDB Length = 325 Score = 44.5 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 52/123 (42%), Gaps = 16/123 (13%) Query: 80 NLYGKDIKEKALIDMYIEGIAD-LGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEK 138 +LY + +K + ID E + D + + F+ ++ + EK Sbjct: 167 HLYPEALKSE--IDEINEWVYDTVNNGVYKAGFATTQQAYEAAVI----PLFESLDRLEK 220 Query: 139 VLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFP-LLKALKTRISNLPTVKKF 197 +L G+DYLVG++L+ AD+ L + D + + F L+ ++ P + + Sbjct: 221 IL--TGKDYLVGDQLTEADVRLFVTII---RFDPAYVGHFKCNLRTIRD---GYPAIHLW 272 Query: 198 LQP 200 L+ Sbjct: 273 LRK 275 >3BBY-A nrPDB Length = 215 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 36/82 (43%), Gaps = 11/82 (13%) Query: 23 LAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQ---VPMVEIDGMKLVQTRAILNYIASKY 79 L G+ F K I + + L+ + Q VP+++ID +L ++ AI Y+ ++ Sbjct: 27 LQEKGLSFHIKTI-DLDSGEHLQPTW-QGYGQTRRVPLLQIDDFELSESSAIAEYLEDRF 84 Query: 80 ------NLYGKDIKEKALIDMY 95 +Y D++ +A Sbjct: 85 APPTWERIYPLDLENRARARQI 106 >1GWC-A nrPDB Length = 230 Score = 41.0 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 77/197 (39%), Gaps = 23/197 (11%) Query: 18 SIRWLLAAAGVEFEEKFIKSAEDLDK---LRNDGYLMFQQVPMVEIDGMKLVQTRAILNY 74 ++ LA G+ +E+ EDL K L + +++P++ +G + ++ IL Y Sbjct: 20 RVKLALALKGLSYEDV----EEDLYKKSELLLKSNPVHKKIPVLIHNGAPVCESMIILQY 75 Query: 75 IASKY-----NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTK 129 I + +L D E+A+ ++ + D + + + ++ K +K Sbjct: 76 IDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWR-QWLRGKTEEEKSE--GKKQA 132 Query: 130 NRYFPAFEKVLKSHGQ--DYLVGNKLSRADIHLVELLYYVEELDS------SLISSFPLL 181 E L+ + + G+ + D+ L +L +++ ++ + PLL Sbjct: 133 FAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSWMKVTEALSGDKIFDAAKTPLL 192 Query: 182 KALKTRISNLPTVKKFL 198 A R L K L Sbjct: 193 AAWVERFIELDAAKAAL 209 >4G0L-A nrPDB Length = 328 Score = 41.0 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 35/160 (21%), Positives = 59/160 (36%), Gaps = 25/160 (15%) Query: 55 VPMVEIDG-MKLV--QTRAILNYIASKYNLYGKD------IKEKALIDMYIEGIAD-LGE 104 VP++ +V ++ I+ + ++ G + ID I D + Sbjct: 133 VPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNN 192 Query: 105 MILLLPFSQPEEQ-DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVEL 163 + F+ +E D +A + E E++L H YL GN+L+ ADI L Sbjct: 193 GVYKAGFATSQEAYDEAVAKVFES-----LARLEQILGQH--RYLTGNQLTEADIRLWTT 245 Query: 164 L-----YYVEEL--DSSLISSFPLLKALKTRISNLPTVKK 196 L YV D IS + L I +P + + Sbjct: 246 LVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAE 285 >6GZF-A nrPDB Length = 341 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 53/123 (43%), Gaps = 22/123 (17%) Query: 55 VPMV---EIDGMKLVQTRAILNYIASKYN--------LYGKDIKEKALIDMYIEGI-ADL 102 VP++ E D + ++ I+ ++++ LY + +EK +D I+ I + Sbjct: 134 VPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYPEGYQEK--VDQIIDNIYEPI 191 Query: 103 GEMILLLPFSQPEEQ-DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLV 161 + F+ +E D +A + ++ VL Q YL G++L+ ADI + Sbjct: 192 NNGVYRAGFATEQEPYDEAVAELFGA-----LAHWDDVLAD--QRYLAGDRLTEADIAMF 244 Query: 162 ELL 164 L Sbjct: 245 TTL 247 >3FY7-A nrPDB Length = 250 Score = 37.2 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 26/170 (15%), Positives = 54/170 (31%), Gaps = 15/170 (8%) Query: 16 MESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 + + +L GV F + + D L+ + Q+P++ D T I +++ Sbjct: 45 CQRLFMVLLLKGVPFTLTTVDTRRSPDVLK--DFAPGSQLPILLYDSDAKTDTLQIEDFL 102 Query: 76 ASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPA 135 L D A + P + Q + Sbjct: 103 EET--LGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALARLDS 160 Query: 136 F-----------EKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSL 174 + E L+ + +L G++L+ AD L+ L+ V+ + + Sbjct: 161 YLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHF 210 >4USS-A nrPDB Length = 325 Score = 36.8 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 57/169 (33%), Gaps = 24/169 (14%) Query: 55 VPMVEIDGMKLV---QTRAILNYIASKYNLYGKDIKEKALID--------MYIEGIADLG 103 VP++ +K + ++ I+ +++N DI E A +D E + Sbjct: 129 VPVLWDKKLKTIVNNESSEIIRMFNTEFN----DIAENAALDLYPSHLQAQIDETNGWVY 184 Query: 104 EMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVEL 163 + I + + E++L Q Y+ GN LS ADI L Sbjct: 185 DGINNGVYKCGFARKQGPYEEAAIQLYEALDKCEEILGR--QRYICGNTLSEADIKLFVT 242 Query: 164 L-------YYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRK 205 L + + L+ +P + I +P + + ++ Sbjct: 243 LIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMSSTVNMQHIKR 291 >4PTS-A nrPDB Length = 348 Score = 36.8 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 42/114 (36%), Gaps = 14/114 (12%) Query: 89 KALIDMYIEGI-ADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDY 147 +A ID +GI ++ + F+ ++ ++ + + L Q Y Sbjct: 168 RAEIDEVSKGIYTEVNNGVYRCGFAGSQD---AYDAAYDRLFTK-LDELSERLAQ--QRY 221 Query: 148 LVGNKLSRADIHLVELLY-----YVEELD--SSLISSFPLLKALKTRISNLPTV 194 LVG+ ++ AD+ L L Y S +S P+L A + P Sbjct: 222 LVGDTITEADVRLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQTPGF 275 >3M1G-A nrPDB Length = 362 Score = 34.1 bits (77), Expect = 0.055, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 8/67 (11%) Query: 133 FPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLP 192 E L + + YL+G+ ++ ADI L L D+ F K + +I+ +P Sbjct: 223 LDWLEDRLST--RRYLMGDHITEADIRLYPTLV---RFDAVYHGHF---KCGRNKITEMP 274 Query: 193 TVKKFLQ 199 + +L+ Sbjct: 275 NLWGYLR 281 >4XRU-B nrPDB Length = 394 Score = 32.9 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 62/142 (43%), Gaps = 3/142 (2%) Query: 64 KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQ--DAKL 121 K+ Q A L+++A L K++K+K + + + + L LP Q Q +L Sbjct: 161 KIQQEPAYLSFVADAKVLSAKELKDKYPMHIIRQYQSIRDFKFLDLPHYQQNIQLFKRQL 220 Query: 122 ALIQEKTKNRYFPA-FEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 + ++ + P K + + G+++ V + LS I+ + L+Y + +P Sbjct: 221 DIFGKEAAPFFKPFNILKEVYTDGREHFVNDNLSFQQINDDDFLHYQFTDREDFEAKYPQ 280 Query: 181 LKALKTRISNLPTVKKFLQPGS 202 ++A +++ ++P + Sbjct: 281 IRAWVDQVNQSDEEGVVIKPRT 302 >2YV7-A nrPDB Length = 260 Score = 31.4 bits (70), Expect = 0.32, Method: Composition-based stats. Identities = 30/190 (15%), Positives = 68/190 (35%), Gaps = 23/190 (12%) Query: 40 DLDKLRNDGYLMFQQV--PMVEIDGMKLVQTRAILNYIASK----YNLYGKDIKEKALID 93 D+ K D F+ P++ +G+ +++ I +I YNL+ +D + LI+ Sbjct: 67 DMQKPPPDFRTNFEATHPPILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKEVATLIE 126 Query: 94 MYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKL 153 + + + K + + L + +L G+ + Sbjct: 127 NL---------------YVKLKLMLVKKDEAKNNALLSHLRKINDHLSARNTRFLTGDTM 171 Query: 154 SRADIHLVELLYYVEELDSSLIS-SFP-LLKALKTRISNLPTVKKFLQPGSPRKPPMDEK 211 D L+ L ++ + P L AL + ++ + F Q + ++ Sbjct: 172 CCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDIINHY 231 Query: 212 SLEESRKIFR 221 L++S K+ + Sbjct: 232 KLQQSLKMKK 241 >2JZR-A nrPDB Length = 144 Score = 31.4 bits (70), Expect = 0.34, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 20/41 (48%) Query: 34 FIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNY 74 F+ +D D + L + ++P+V +G + Q+ I Y Sbjct: 68 FLHEKKDGDFQKWYAGLNYPKLPVVTDNGGTIAQSLNISVY 108 >4K0G-A nrPDB Length = 251 Score = 31.0 bits (69), Expect = 0.44, Method: Composition-based stats. Identities = 27/171 (15%), Positives = 55/171 (32%), Gaps = 25/171 (14%) Query: 17 ESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIA 76 + + +L GV F + + + ++ Q+P + T I ++ Sbjct: 38 QRLFMVLWLKGVTFNVTTVDTKRRTETVQ--KLCPGGQLPFLLYGTEVHTDTNKIEEFLE 95 Query: 77 SKYNLYG-KDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPA 135 + L + K AL D+ + + L EK + Sbjct: 96 AV--LCPPRYPKLAALNPESNTAGLDIFAKFSAYI----KNSNPALNDNLEKGLLKALKV 149 Query: 136 FEKVLKS----------------HGQDYLVGNKLSRADIHLVELLYYVEEL 170 + L S + +L GN+L+ AD +L+ L+ V+ + Sbjct: 150 LDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVV 200 >3IR4-A nrPDB Length = 218 Score = 30.6 bits (68), Expect = 0.54, Method: Composition-based stats. Identities = 33/171 (19%), Positives = 64/171 (37%), Gaps = 14/171 (8%) Query: 20 RWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVE-IDGMKLVQTRAILNYIASK 78 R + + E +++ D+ + + VP+++ D L ++ I++Y+ Sbjct: 19 RMIFGLKNIPVELNVLQND---DEATPTRMIGQKMVPILQKDDSRYLPESMDIVHYVD-- 73 Query: 79 YNLYGK---DIKEKALIDMYIEGIADLGEMILLLPFSQ---PEEQDAKLALIQEKTKNRY 132 NL GK K I+ ++ + +LL F++ E + K Sbjct: 74 -NLDGKPLLTGKRNPAIEEWLRKVNGYVNQLLLPRFAKSAFDEFSTPAARQYFIRKKEAS 132 Query: 133 FPAFEKVLKSHGQDY-LVGNKLSRADIHLVELLYYVEELDSSLISSFPLLK 182 +F+ L +G+ L D +V+ EL I FPLL+ Sbjct: 133 SGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGELSEDDIHLFPLLR 183 >5Y7I-A nrPDB Length = 261 Score = 30.2 bits (67), Expect = 0.66, Method: Composition-based stats. Identities = 26/180 (14%), Positives = 55/180 (30%), Gaps = 37/180 (20%) Query: 16 MESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYI 75 + + +L GV+F + + +L+ P + +G I ++ Sbjct: 49 CQRLFMVLWLKGVKFTVTTVDMRKKPAELK--DLAPGTNPPFLLYNGTLKTDFIKIEEFL 106 Query: 76 ASKY------NLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTK 129 +L + + + AD+ + P +QEK Sbjct: 107 EQTLAPPRYPHLSPVNKES-------FDVGADIFAKFSAFIKNSPNN------PLQEKNL 153 Query: 130 NRYFPAFEKVLKS----------------HGQDYLVGNKLSRADIHLVELLYYVEELDSS 173 R F + L S + +L G++L+ AD +L+ L+ + Sbjct: 154 LREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVIRVAAKK 213 >5LKB-A nrPDB Length = 378 Score = 30.2 bits (67), Expect = 0.73, Method: Composition-based stats. Identities = 17/106 (16%), Positives = 31/106 (29%), Gaps = 24/106 (22%) Query: 94 MYIEGIADLGEMILLLP----FSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSH------ 143 I D + + + A++ + + EK+L Sbjct: 203 QLKTQIDDFNSWVYDSINNGVYKTGFAEKAEVYESEVNNVFEHLDKVEKILSDKYSKLKA 262 Query: 144 -----------GQDYLVGNKLSRADIHLVELLYYVEELDSSLISSF 178 G+ + VG++L+ ADI L V D + F Sbjct: 263 KYGEEDRQKILGEFFTVGDQLTEADIRLY---TTVIRFDPVYVQHF 305 >1OYJ-A nrPDB Length = 231 Score = 29.9 bits (66), Expect = 0.95, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 16 MESIRWLLAAAGVEFE--EKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILN 73 + R +A G+EFE E+ + + DL N + +++P++ G + ++ IL Sbjct: 18 GQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVH---RKIPVLLHAGRPVSESLVILQ 74 Query: 74 YIASKY 79 Y+ + Sbjct: 75 YLDDAF 80 >4LMW-A nrPDB Length = 251 Score = 29.1 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 31/224 (13%), Positives = 69/224 (30%), Gaps = 51/224 (22%) Query: 19 IRWLLAAAGVEFEEKFIK---------SAEDLDKLRNDGYLMFQQVPMVEIDGMK--LVQ 67 R++L G+++ ++++ + +P+++ K + Sbjct: 28 TRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYTLPVIQDPNTKAVVAD 87 Query: 68 TRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLP----------------- 110 + AI Y+ S Y + E + L +L+P Sbjct: 88 SDAIAKYLESTYPDTPRLFPEGTR--AFQHAFYQLARPSVLMPIFNIVVARVWKLLRPRS 145 Query: 111 --FSQPEEQDAKLALIQEKTKNRYFPAFEKVLK---------SHGQDYLV-GNKLSRADI 158 + + + ++E + A E L G+D L+ G++++ AD+ Sbjct: 146 QEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKDLLLMGDRVTFADL 205 Query: 159 HLVELLYYVEELDSSLISSFPLLKALKTRISNLP--TVKKFLQP 200 L L ++ R +L KF+Q Sbjct: 206 QLASLFIWLRVSAGEESED-------WKRFLSLHEGKWAKFMQQ 242 >4CZI-A nrPDB Length = 348 Score = 28.3 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 58 VEIDGMKLVQTRAILNYIASKYNLY-GKDIKEKAL 91 V + G K+ + AI++Y+ +NL G+ E+ Sbjct: 177 VRVGGDKMDE--AIISYMRRHHNLLIGETTAERIK 209 >2H30-A nrPDB Length = 164 Score = 28.3 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 19/41 (46%) Query: 34 FIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNY 74 F+ +D + + L + ++P+V +G + Q I Y Sbjct: 82 FLHEKKDGEFQKWYAGLNYPKLPVVTDNGGTIAQNLNISVY 122 >2JB2-A nrPDB Length = 489 Score = 27.5 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 9/23 (39%), Positives = 14/23 (60%) Query: 134 PAFEKVLKSHGQDYLVGNKLSRA 156 P +EK+L+ + Y G+ LS A Sbjct: 441 PEYEKLLEPVDKIYFAGDHLSNA 463 >6EN4-C nrPDB Length = 852 Score = 27.5 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 25/180 (13%), Positives = 57/180 (31%), Gaps = 26/180 (14%) Query: 44 LRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYI---EGIA 100 +++ +P ++ D ++ + + L ++ KE+ ++ + + G Sbjct: 1 MKSVNDQPSGNLPFLKPDDIQYFDKLLVD---VDESTLSPEEQKERKIMKLLLKIKNGTP 57 Query: 101 DLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEK-VLKSHGQDYLVGNKLSRADIH 159 + + L + D N+ P L+ + LV D Sbjct: 58 PMRKAALR------QITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLV----KVIDRI 107 Query: 160 LVELLYYVE-ELDSSLISSFPLL--KALKTRISNLPTVKKFLQPG------SPRKPPMDE 210 L +L V + L+ PLL + R+ + + S +P +D Sbjct: 108 LYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDN 167 >5VAT-A nrPDB Length = 543 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 6/34 (17%) Query: 68 TRAI--LNYIASKYNLYGKDIKEKALIDMYIEGI 99 +RAI L Y Y L +D E A M+ +G+ Sbjct: 317 SRAIPQLCY----YGLSPEDEAESAANKMWNDGV 346 >3QAO-A nrPDB Length = 249 Score = 27.2 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 29/86 (33%), Gaps = 1/86 (1%) Query: 63 MKLVQTR-AILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKL 121 + L ++ A ++AS L + + + ID + + D I L + Sbjct: 160 LTLKESFDAEFRHLASVRKLTPESEEAQLEIDHFFHYLNDTHGNIYSLEAFASLGEMYVN 219 Query: 122 ALIQEKTKNRYFPAFEKVLKSHGQDY 147 K +++ + L+ Y Sbjct: 220 DERFTKNIDQFGDGLSQFLQEAMTIY 245 >5E1J-A nrPDB Length = 741 Score = 26.8 bits (58), Expect = 8.0, Method: Composition-based stats. Identities = 27/119 (22%), Positives = 49/119 (41%), Gaps = 15/119 (12%) Query: 87 KEKA--LIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHG 144 EKA LID G D + I L EQ + + +K + F+++ Sbjct: 327 LEKAFGLIDSDKNGEIDKNQCIKLF------EQLTNYRTLPKISKEEFGLIFDEL--DDT 378 Query: 145 QDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSP 203 +D+ + NK AD+ L + +E SL FP + + +S ++ F++ + Sbjct: 379 RDFKI-NKDEFADLCQAIALRFQKEEVPSLFEHFPQI--YHSALSQ--QLRAFVRSPNF 432 >5T2A-v nrPDB Length = 348 Score = 26.4 bits (57), Expect = 9.0, Method: Composition-based stats. Identities = 17/118 (14%), Positives = 37/118 (31%), Gaps = 13/118 (11%) Query: 114 PEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRA-D---IHLVELLYYVEE 169 P ++ K + PA + +++ +G + A D ++ Sbjct: 86 PGKEVKKATQPAKAASPYKKPAVASHFAARPKNFGIGQDVPYARDLSRFMRWPTFVTMQR 145 Query: 170 LDSSL---------ISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 L ++ F + +R L +KK+ + K+ EE +K Sbjct: 146 KKRVLQRRLKVPPALNQFTKVLDRASRNEALKLIKKYAPETRKARRERLHKAAEEKKK 203 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.152 0.432 Lambda K H 0.267 0.0464 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,324,364 Number of Sequences: 36641 Number of extensions: 392825 Number of successful extensions: 1625 Number of sequences better than 10.0: 143 Number of HSP's better than 10.0 without gapping: 180 Number of HSP's successfully gapped in prelim test: 57 Number of HSP's that attempted gapping in prelim test: 1198 Number of HSP's gapped (non-prelim): 241 length of query: 222 length of database: 10,336,785 effective HSP length: 93 effective length of query: 129 effective length of database: 6,929,172 effective search space: 893863188 effective search space used: 893863188 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (26.8 bits)