BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09110 (424 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IIK-A nrPDB 799 0.0 2WUA-A nrPDB 441 e-124 2C7Y-A nrPDB 441 e-124 1PXT-A nrPDB 372 e-103 4DD5-A nrPDB 282 2e-76 4N44-A nrPDB 281 3e-76 4E1L-A nrPDB 277 7e-75 1ULQ-A nrPDB 271 4e-73 3SS6-A nrPDB 264 6e-71 4NZS-A nrPDB 262 2e-70 3GOA-A nrPDB 261 3e-70 1NL7-A nrPDB 258 5e-69 4O9A-A nrPDB 257 6e-69 1WDK-C nrPDB 256 2e-68 4WYS-A nrPDB 248 4e-66 1WL4-A nrPDB 245 2e-65 4C2K-A nrPDB 233 1e-61 5LP7-H nrPDB 232 2e-61 5CBQ-A nrPDB 230 1e-60 3SVK-A nrPDB 214 5e-56 6BN2-A nrPDB 213 9e-56 4B3J-C nrPDB 207 5e-54 4UBW-A nrPDB 207 9e-54 5ZQZ-B nrPDB 203 1e-52 6BJA-A nrPDB 188 3e-48 6ARG-A nrPDB 186 1e-47 6BJB-A nrPDB 185 3e-47 5XYJ-B nrPDB 184 5e-47 2IBU-A nrPDB 181 4e-46 6ESQ-A nrPDB 62 6e-10 6HRV-A nrPDB 54 9e-08 5LNQ-A nrPDB 49 3e-06 4BI9-A nrPDB 47 2e-05 5M3K-C nrPDB 32 0.38 4YZO-A nrPDB 30 2.0 1X1P-A nrPDB 30 2.4 2GP6-A nrPDB 29 3.8 1J3N-A nrPDB 28 7.0 4JD3-A nrPDB 28 7.8 >2IIK-A nrPDB Length = 418 Score = 799 bits (2063), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/397 (99%), Positives = 396/397 (99%) Query: 28 SGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC 87 S APQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC Sbjct: 22 SMAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC 81 Query: 88 VGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMA 147 VGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMA Sbjct: 82 VGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMA 141 Query: 148 CGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQ 207 CGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQ Sbjct: 142 CGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQ 201 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 267 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD Sbjct: 202 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 261 Query: 268 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 327 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV Sbjct: 262 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 321 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 387 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV Sbjct: 322 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 381 Query: 388 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN 424 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN Sbjct: 382 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN 418 >2WUA-A nrPDB Length = 440 Score = 441 bits (1134), Expect = e-124, Method: Compositional matrix adjust. Identities = 221/389 (56%), Positives = 293/389 (75%), Gaps = 7/389 (1%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV+V R+ +C+A RGG KDT PD++L+ V+ A+++ N+ P ++GDI VG+VL GA Sbjct: 34 DVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVL--GA 91 Query: 97 GAIMA---RIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G+ A R+A F + PETVP+ TVNRQCSSGLQAVA +A I+ G YDIG+ G+ESM Sbjct: 92 GSQRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESM 151 Query: 154 SLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARA 213 + G++ ++ +A+DCL+PMGITSENVA++F I+R++QD A+ S +K A A Sbjct: 152 TANPMAWEGSVNPKVKTMAQAQDCLLPMGITSENVAQKFSITRQEQDQAAVGSHRKTAAA 211 Query: 214 QSKGCFQAEIVPVTTTVHDDK-GTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTA 272 + G F+ EI+P+ T + D K G ++ +T++ D+GIRP T++ LAKLKP F+KDGSTTA Sbjct: 212 TAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDGIRPGTSLADLAKLKPVFRKDGSTTA 271 Query: 273 GNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKA 332 G SSQVSDGA A+LL +RS A + GLPILGV R++A VGVPP IMGIGPA AIP A++ A Sbjct: 272 GTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRTFAAVGVPPSIMGIGPAVAIPAAVKAA 331 Query: 333 GLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLN 392 GL + D+D+FEINEAFASQ YC +KL + P+K+N GGA+A+GHPLG TGAR V TLL+ Sbjct: 332 GLQIDDIDLFEINEAFASQFVYCQKKLEIDPQKINVNGGAMAIGHPLGATGARCVATLLH 391 Query: 393 ELKRRGKRA-YGVVSMCIGTGMGAAAVFE 420 E+KRRG+ +GVVSMCIGTGMGAAAVFE Sbjct: 392 EMKRRGRDCRFGVVSMCIGTGMGAAAVFE 420 >2C7Y-A nrPDB Length = 404 Score = 441 bits (1134), Expect = e-124, Method: Compositional matrix adjust. Identities = 227/387 (58%), Positives = 291/387 (75%), Gaps = 3/387 (0%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV+V RT +C++ RG FKDT PD+LL+ V+ A+++ NL P ++GDI VG VL PG+ Sbjct: 14 DVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGS 73 Query: 97 G-AIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155 A R+A F + PETV + TVNRQCSSGLQAVA +A I+ G YDIG+ G+ESM+ Sbjct: 74 QRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTT 133 Query: 156 ADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQS 215 G++ + + +A++CL+PMG+TSENVA+RFG+SR++QD A+ S +KAA A + Sbjct: 134 NPMAWEGSVNPAVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAAVDSHRKAAAATA 193 Query: 216 KGCFQAEIVPVTTTVHDDK-GTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGN 274 G F+ EI+PV T + D K G ++ ITV+ D+GIRP+TT+ L KLKP FKKDG+TTAGN Sbjct: 194 AGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKPVFKKDGTTTAGN 253 Query: 275 SSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGL 334 SSQVSDGA A+LL +RS A + GLP+LGV R++A VGV P IMGIGPA AIP A++ AGL Sbjct: 254 SSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGPAVAIPAAVKAAGL 313 Query: 335 TVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNEL 394 + D+D+FEINEAFASQ YC KL L PEK+N GGA+A+GHPLG TGAR V TLL+E+ Sbjct: 314 ELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEM 373 Query: 395 KRRGKRA-YGVVSMCIGTGMGAAAVFE 420 KRRGK +GVVSMCIGTGMGAAAVFE Sbjct: 374 KRRGKDCRFGVVSMCIGTGMGAAAVFE 400 >1PXT-A nrPDB Length = 390 Score = 372 bits (956), Expect = e-103, Method: Compositional matrix adjust. Identities = 212/395 (53%), Positives = 260/395 (65%), Gaps = 27/395 (6%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVL--------KDVNLRPEQLGDICV 88 DVV+V R+AI + +G FKD D LL + + D+NL E + Sbjct: 8 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE----VAC 63 Query: 89 GNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMAC 148 GNVL GAGA R A S IP + P +NRQCSSGL AV IA I+ G DIG+A Sbjct: 64 GNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 123 Query: 149 GVESMSLADRG-NP-GNITSRLMEKEK-ARDCLIPMGITSENVAERFGISREKQDTFALA 205 GVESM+ + NP G I+S ++K + A+ CLIPMGIT+ENVA F ISR+ QD FA Sbjct: 124 GVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAAN 183 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 S QKA +A+++G F+ EI+P+ K SI DEG RP+ T E L+ ++PAF Sbjct: 184 SYQKAYKAKNEGLFEDEILPI-------KLPDGSIC-QSDEGPRPNVTAESLSSIRPAFI 235 Query: 266 KD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYA 324 KD G+TTAGN+SQVSDG A +LLARRS A +L LP+LG + VGVPP+IMG+GPAYA Sbjct: 236 KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 295 Query: 325 IPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 IP L+ GL V D+DIFEINEAFA+QA YC+ KL + KVNP GGA+ALGHPLGCTGA Sbjct: 296 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 355 Query: 385 RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVF 419 RQV T+L ELK K GVVSMCIGTGMGAAA+F Sbjct: 356 RQVATILRELK---KDQIGVVSMCIGTGMGAAAIF 387 >4DD5-A nrPDB Length = 396 Score = 282 bits (721), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 167/397 (42%), Positives = 233/397 (58%), Gaps = 22/397 (5%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 +VV+ RTA+ G G FK + EL +K N+ P+ + + +G VL G Sbjct: 8 EVVIASAARTAVGSFG-GAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTAGL 66 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL- 155 G +AR + IP P T+N C SGL++V+ + I G DI + G E+MS+ Sbjct: 67 GQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMSMS 126 Query: 156 ----------ADRGNPGNITSRLMEKEKARDCL--IPMGITSENVAERFGISREKQDTFA 203 A G+ + S M K+ D MGIT+EN+AE++ I+RE+QD A Sbjct: 127 PYLVPSARYGARMGDAAFVDS--MIKDGLSDIFNNYHMGITAENIAEQWNITREEQDELA 184 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 LASQ KA +AQ++G F EIVPV KG K V +DE I+P TTME LAKL+PA Sbjct: 185 LASQNKAEKAQAEGKFDEEIVPVVI-----KGRKGDTVVDKDEYIKPGTTMEKLAKLRPA 239 Query: 264 FKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 FKKDG+ TAGN+S ++DGAA +++ + KAEELG+ L + SY GV P IMG GP Sbjct: 240 FKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPVP 299 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 A AL+ A +T+ D+D+ E NEAFA+Q+ + L + KVN GGA+A+GHP+GC+G Sbjct: 300 ATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCSG 359 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 AR + TLL E+KRR + G+ ++CIG GMG + + Sbjct: 360 ARILTTLLYEMKRRDAKT-GLATLCIGGGMGTTLIVK 395 >4N44-A nrPDB Length = 400 Score = 281 bits (720), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 168/395 (42%), Positives = 238/395 (60%), Gaps = 18/395 (4%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 +VV+ RTAI G+ KD +L + + +K ++PE + ++ +GNVLQ G Sbjct: 3 EVVIASAVRTAIGSYGKS-LKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAGL 61 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS-- 154 G AR A F + +P +P T+N+ C SGL+ V+ A I+ G D+ +A G+E+MS Sbjct: 62 GQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSRA 121 Query: 155 --LADRGNPG-NITSRLMEKEKARDCL------IPMGITSENVAERFGISREKQDTFALA 205 LA+ G + + E D L MGIT+EN+AER+ ISRE+QD FALA Sbjct: 122 PYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFALA 181 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 SQ+KA A G F+ EIVPV KG K V DE R +T+EGLAKLKPAFK Sbjct: 182 SQKKAEEAIKSGQFKDEIVPVVI-----KGRKGETVVDTDEHPRFGSTIEGLAKLKPAFK 236 Query: 266 KDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 325 KDG+ TAGN+S ++D AA +++ KA+ELG+ L + SY GV P IMG GP YA Sbjct: 237 KDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYAT 296 Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 A++KAG TV ++D+ E NEAFA+Q+ + L+ KVN GGA+ALGHP+G +GAR Sbjct: 297 KAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGAR 356 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 ++TL++ +++R + G+ ++CIG G G A + E Sbjct: 357 ILVTLVHAMQKRDAKK-GLATLCIGGGQGTAILLE 390 >4E1L-A nrPDB Length = 395 Score = 277 bits (708), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 168/396 (42%), Positives = 237/396 (59%), Gaps = 23/396 (5%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV+V RT I G G FK+T+ +L + + + V L ++ ++ +GNVLQ G Sbjct: 6 DVVIVSAVRTPIGSFG-GVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQTGL 64 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G +AR + IP +VP TVN+ C SGL++V A I +G D+ +A G E+MS A Sbjct: 65 GQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENMSQA 124 Query: 157 DRGNP--------GNITSRLMEKEKARDCLIP------MGITSENVAERFGISREKQDTF 202 P GNIT M D LI MGIT+EN+A +F +RE QD Sbjct: 125 PYIVPTARFGSKMGNIT---MVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQDKL 181 Query: 203 ALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKP 262 AL SQ KA A F+ EIVPV + K T+ +DE + T EGL+KLKP Sbjct: 182 ALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIE----TIDKDEYPKLGMTFEGLSKLKP 237 Query: 263 AFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPA 322 AFKKDG+ TAGN+S ++DGAA ++L + KA+ELG+ L ++SYA GV P++MG GP Sbjct: 238 AFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPI 297 Query: 323 YAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCT 382 A AL+KAGL+++D+D+ E NEAFA+QA +L++ K+N GGA+ALGHP+G + Sbjct: 298 PATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGAS 357 Query: 383 GARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAV 418 GAR ++TL+ E+++R K G+ ++CIG G G + V Sbjct: 358 GARILVTLIYEMQKR-KVETGLATLCIGGGQGISMV 392 >1ULQ-A nrPDB Length = 401 Score = 271 bits (693), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 175/403 (43%), Positives = 237/403 (58%), Gaps = 26/403 (6%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 + +V RT I + G G PD+LL+ ++ ++ + E++ D+ G Q G Sbjct: 3 EAWIVEAVRTPIGKHG-GALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAGE 61 Query: 97 -GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155 +AR+A L+ P V TVNR C SGL+AVA A I G + + GVESMS Sbjct: 62 DNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMSR 121 Query: 156 A-------DRGNP-GNIT-------SRLME-KEKARDCLIPMGITSENVAERFGISREKQ 199 A +RG P GN+ R + K +A MG T+EN+AE +GI RE+Q Sbjct: 122 APYAVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIRREEQ 181 Query: 200 DTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAK 259 D FAL S QKA RA +G FQ E+VPV K K I V QDEG R T++E LA Sbjct: 182 DRFALLSHQKAVRAWEEGRFQDEVVPVPV-----KRGKEEILVEQDEGPRRDTSLEKLAA 236 Query: 260 LKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGI 319 L+P F++ G+ TAGNSS ++DGAAA+LL A+ GL L +R+ AV GVPP IMGI Sbjct: 237 LRPVFREGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGI 296 Query: 320 GPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPE--KVNPLGGAVALGH 377 GP A AL++AGL+ SD+ + E+NEAFA+QA + + L E ++NP GGA+ALGH Sbjct: 297 GPVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGH 356 Query: 378 PLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 PLG +GAR + TL++E++RR K +G+ +MCIG G G A V E Sbjct: 357 PLGASGARILTTLVHEMRRR-KVQFGLATMCIGVGQGIAVVVE 398 >3SS6-A nrPDB Length = 394 Score = 264 bits (674), Expect = 6e-71, Method: Compositional matrix adjust. Identities = 160/394 (40%), Positives = 226/394 (57%), Gaps = 17/394 (4%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 +VV+ R+ I G G K+ TP EL V+ +K + P ++ ++ +G+ +Q Sbjct: 6 NVVITAAVRSPIGTFG-GALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRTD 64 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS-- 154 A AR A + P+TV T+ RQCSSG+QA+ S A I+ G ++ +A GVE+MS Sbjct: 65 EANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAMSSS 124 Query: 155 --------LADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALAS 206 R G I + E + I MG T+EN+ E++ I+RE+QD AL S Sbjct: 125 PYALKQHRWGQRLQHGEIRDTVWEVLEDPIHHIMMGETAENLVEQYEITREEQDEVALRS 184 Query: 207 QQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKK 266 A +A G F +IVP+T K ++ + ++DE R T E LA LKPAF+K Sbjct: 185 HTLALKAIESGYFDDQIVPITI-----KERRKEVVFSKDEHPRADITAEKLAGLKPAFRK 239 Query: 267 DGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIP 326 DGS TAGN+S ++DG+A ++L KA+E GL L + Y+V GV P IMGIGPA AI Sbjct: 240 DGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIR 299 Query: 327 VALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQ 386 L+K ++ D D+ EINEAFA+Q ++L L EKVN G V LGHP+GCTGAR Sbjct: 300 KGLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPIGCTGARI 359 Query: 387 VITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 ++L++ELKRRG G+ S+C+G G+G A E Sbjct: 360 TVSLIHELKRRGLEK-GIASLCVGGGIGVALFIE 392 >4NZS-A nrPDB Length = 399 Score = 262 bits (670), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 165/396 (41%), Positives = 223/396 (56%), Gaps = 19/396 (4%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPG- 95 +VVVV G RTAI G G KD P EL + V+ L + + +G + GNV+Q Sbjct: 9 EVVVVSGVRTAIGTFG-GSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEP 67 Query: 96 AGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155 + R+A + P TVNR C SGLQA+ S A I G D+ + G ESMS Sbjct: 68 RDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSR 127 Query: 156 ADRGNPGNITSRLMEKEKARDCL----------IPMGITSENVAERFGISREKQDTFALA 205 A P M D + I MG+T+ENVA+ + ISR +QD AL Sbjct: 128 APYLAPAARWGARMGDAGLVDMMLGALHDPFHRIHMGVTAENVAKEYDISRAQQDEAALE 187 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF- 264 S ++A+ A G F+ +IVPV + KG K +T DE +R T++ + KL+P F Sbjct: 188 SHRRASAAIKAGYFKDQIVPVVS-----KGRKGDVTFDTDEHVRHDATIDDMTKLRPVFV 242 Query: 265 KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYA 324 K++G+ TAGN+S ++D AAA+++ R++AE GL L L SY GV P MGIGP A Sbjct: 243 KENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPVPA 302 Query: 325 IPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 +AL++AGL VSD+D+ E NEAFA+QA + L L P KVNP G ++LGHP+G TGA Sbjct: 303 TKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGATGA 362 Query: 385 RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 + L+EL R R Y +V+MCIG G G AA+FE Sbjct: 363 LITVKALHELNRVQGR-YALVTMCIGGGQGIAAIFE 397 >3GOA-A nrPDB Length = 387 Score = 261 bits (668), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 170/396 (42%), Positives = 232/396 (58%), Gaps = 27/396 (6%) Query: 38 VVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVL-KDVNLRPEQLGDI---CVGNVLQ 93 VV+V RT + R+ G F++ ++L + +M ++L ++ +L L DI CV L+ Sbjct: 4 VVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQTLE 63 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G +AR A L++IP +VP TVNR C S +QA+ A I G + + GVE M Sbjct: 64 QGFN--IARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEHM 121 Query: 154 -----SLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQ 208 S +PG SR + K MG+T+E ++ GISRE QD FA S Sbjct: 122 GHVPMSHGVDFHPG--LSRNVAKAAGM-----MGLTAEMLSRLHGISREMQDQFAARSHA 174 Query: 209 KAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKK-D 267 +A A G F+ EI+P T HD G + DE IRP TT+E L+ L+PAF Sbjct: 175 RAWAATQSGAFKTEIIP--TGGHDADGVLKQFNY--DEVIRPETTVEALSTLRPAFDPVS 230 Query: 268 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 327 G+ TAG SS +SDGAAA+L+ S+A ELGL +RS AVVG P IMG GP A + Sbjct: 231 GTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKL 290 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPP---EKVNPLGGAVALGHPLGCTGA 384 AL+KAGL+ SD+D+FE+NEAFA+Q C++ L L EK+N GGA+ALGHPLGC+GA Sbjct: 291 ALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGA 350 Query: 385 RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 R TL+N ++R+ + +G+ +MCIG G G A VFE Sbjct: 351 RISTTLINLMERKDAQ-FGLATMCIGLGQGIATVFE 385 >1NL7-A nrPDB Length = 392 Score = 258 bits (658), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 164/397 (41%), Positives = 233/397 (58%), Gaps = 17/397 (4%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ 93 S +V+ RTA+ + G F +T EL + V++AVL+ + ++ ++ +G VL Sbjct: 1 STPSIVIASAARTAVG-SFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLP 59 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G G AR A + +P+ +N+ C SGL+AVA I G I +A G+ESM Sbjct: 60 AGEGQNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESM 119 Query: 154 SLAD-----RGNPGNITSRLME---KEKARDCLI--PMGITSENVAERFGISREKQDTFA 203 S+A RG ++++ K+ D MG T+ENVA+++ +SR++QD FA Sbjct: 120 SMAPHCAHLRGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFA 179 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 +ASQ KA AQ G F+ EIVP KG K ITV DE IR T++ +AKL+PA Sbjct: 180 VASQNKAEAAQKDGRFKDEIVPFIV-----KGRKGDITVDADEYIRHGATLDSMAKLRPA 234 Query: 264 FKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 F K+G+ TAGN+S ++DGAAA LL ++A G+ LG + S+A VGV P +MG GP Sbjct: 235 FDKEGTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIP 294 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 A AL++AG + D+D+ E NEAFA+QA + L P VN GGA+A+GHP+G +G Sbjct: 295 ASRKALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASG 354 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 AR + TLL E+KRRG R G+ ++CIG GMG A E Sbjct: 355 ARILNTLLFEMKRRGAR-KGLATLCIGGGMGVAMCIE 390 >4O9A-A nrPDB Length = 398 Score = 257 bits (657), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 165/395 (41%), Positives = 231/395 (58%), Gaps = 17/395 (4%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV+V RTA+ + G G EL + V+ A L+ ++PEQ+ ++ +G VL G+ Sbjct: 8 DVVIVSAARTAVGKFG-GSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGS 66 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G AR A + +P VP T+N+ SGL+AV A I G +I +A G E+MS A Sbjct: 67 GQNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAA 126 Query: 157 DRGNPGNITSRLMEKEKARDCLI-----------PMGITSENVAERFGISREKQDTFALA 205 PG+ M K D +I MGIT+ENVA+ +GI+RE QD FA+ Sbjct: 127 PHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVG 186 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 SQ KA AQ G F EIVPV + KG + DE +R T++ ++ LKPAF Sbjct: 187 SQNKAEAAQKAGKFDEEIVPVL--IPQRKGD--PVAFKTDEFVRQGATLDSMSGLKPAFD 242 Query: 266 KDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 325 K G+ TA N+S ++DGAAA+++ +KA+ELGL L ++SYA GV P +MG+GP A Sbjct: 243 KAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPAS 302 Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 AL +A T D+D+ EINEAFA+QA +++ KVN GGA+A+GHP+G +G R Sbjct: 303 KRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCR 362 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 ++TLL+E+KRR + G+ S+CIG GMG A E Sbjct: 363 ILVTLLHEMKRRDAK-KGLASLCIGGGMGVALAVE 396 >1WDK-C nrPDB Length = 390 Score = 256 bits (653), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 160/395 (40%), Positives = 236/395 (59%), Gaps = 23/395 (5%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVL-KDVNLRPEQLGDI---CVGNVL 92 DVV+V RT + R+ G ++T +++ + +++ VL ++ + P ++ D+ CV L Sbjct: 6 DVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQTL 65 Query: 93 QPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 + G +AR+A ++ IP T TV+R C S + A+ + A I G+ D+ + GVE Sbjct: 66 EQGWN--IARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEH 123 Query: 153 M---SLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQK 209 M S+ +P S K MG+T+E + + GISRE+QD FA+ S Q Sbjct: 124 MGHVSMMHGVDPNPHMSLYAAKASGM-----MGLTAEMLGKMHGISREQQDAFAVRSHQL 178 Query: 210 AARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK-KDG 268 A +A +G F+ EI+P+ +D+ G + DE IRP TT+E LA LKPAF K G Sbjct: 179 AHKATVEGKFKDEIIPMQG--YDENGFLK--IFDYDETIRPDTTLESLAALKPAFNPKGG 234 Query: 269 STTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVA 328 + TAG SSQ++DGA+ +++ +A++LGL L V+RS AV GV P IMG GP A A Sbjct: 235 TVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKA 294 Query: 329 LQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPP---EKVNPLGGAVALGHPLGCTGAR 385 L++AGL ++D+D E+NEAFA+QA ++ L++ EKVN GGA+ALGHP GC+GAR Sbjct: 295 LKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGAR 354 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 TLLN +K+ G +G+ +MCIG G G A VFE Sbjct: 355 ISGTLLNVMKQNGG-TFGLSTMCIGLGQGIATVFE 388 >4WYS-A nrPDB Length = 405 Score = 248 bits (633), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 165/401 (41%), Positives = 232/401 (57%), Gaps = 29/401 (7%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 + V+V RTAI + G T+ +L + V+ A ++ + + + ++ +GNVLQ G Sbjct: 6 NCVIVSAVRTAIG-SFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGL 64 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G AR A S + ETV TVN+ C SGL++VA A I+ G +A G+E+MSLA Sbjct: 65 GQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLA 124 Query: 157 -----------DRGNPGNITSRLMEKEKARDCLI------PMGITSENVAERFGISREKQ 199 R G + ++ RD L+ MGIT+ENVA+ +GI+RE Q Sbjct: 125 PYLLDAKARSGYRLGDGQVYDVIL-----RDGLMCATHGYHMGITAENVAKEYGITREMQ 179 Query: 200 DTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAK 259 D AL SQ+KAA A G F AEIVPV K++ +QDE + ++T E L Sbjct: 180 DELALHSQRKAAAAIESGAFTAEIVPVNVVTR-----KKTFVFSQDEFPKANSTAEALGA 234 Query: 260 LKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGI 319 L+PAF K G+ TAGN+S ++DGAAA+++ S A GL L ++SYA GVPP +MG+ Sbjct: 235 LRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGM 294 Query: 320 GPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPL 379 GP A ALQ AGL ++D+D+ E NEAFA+Q + L EKVN GGA+ALGHP+ Sbjct: 295 GPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPI 354 Query: 380 GCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 G +GAR ++TLL+ ++ R K G+ ++CIG G G A V E Sbjct: 355 GASGARILVTLLHAMQARDK-TLGLATLCIGGGQGIAMVIE 394 >1WL4-A nrPDB Length = 397 Score = 245 bits (626), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 164/393 (41%), Positives = 225/393 (57%), Gaps = 23/393 (5%) Query: 38 VVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAG 97 VV+V RT I + G +L S V+ VLK + PE + ++ G+VL G G Sbjct: 8 VVIVSAART-IIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCG 66 Query: 98 AIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLAD 157 R A + IP +VP + C SGL+AV I G I +A G+E+MS A Sbjct: 67 QNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAP 126 Query: 158 R----------GNPGNITSRLME--KEKARDCLIPMGITSENVAERFGISREKQDTFALA 205 G S L + + +C MGIT+ENVA+++ +SRE QD A+ Sbjct: 127 HLAYLRTGVKIGEMPLTDSILCDGLTDAFHNC--HMGITAENVAKKWQVSREDQDKVAVL 184 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 SQ + AQ G F EIVPV + K I V DE R + +E ++KLKP F Sbjct: 185 SQNRTENAQKAGHFDKEIVPVLVSTR-----KGLIEVKTDEFPRHGSNIEAMSKLKPYFL 239 Query: 266 KDGS--TTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 DG+ T N+S ++DGAAA++L ++S+A++ GL L + S++ VGV P IMGIGP Sbjct: 240 TDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIP 299 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 AI A+ KAG ++ DVDIFEINEAFA+ +A V++L L PEKVN GGA+ALGHPLG +G Sbjct: 300 AIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASG 359 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAA 416 R ++TLL+ L+R G R+ GV ++CIG GMG A Sbjct: 360 CRILVTLLHTLERMG-RSRGVAALCIGGGMGIA 391 >4C2K-A nrPDB Length = 417 Score = 233 bits (594), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 154/395 (38%), Positives = 210/395 (53%), Gaps = 19/395 (4%) Query: 38 VVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAG 97 V VV +RT G G KD T +L A L + PE + + +GNVLQ + Sbjct: 27 VFVVAAKRTPFGAYG-GLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 85 Query: 98 AI-MARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 AI +AR IP+ P T+NR C SG Q++ + I ++ + G ESMS A Sbjct: 86 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 145 Query: 157 -----------DRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALA 205 G+ + L + +PM +T+EN+A + ISRE+ D +AL Sbjct: 146 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 205 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 SQQ+ A G F E+ P+ V KG + T+ DE RP TT+E L KL P FK Sbjct: 206 SQQRWKAANDAGYFNDEMAPIE--VKTKKGKQ---TMQVDEHARPQTTLEQLQKLPPVFK 260 Query: 266 KDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 325 KDG+ TAGN+S V+DGA A+++A ++ L + Y V G P IMGIGP AI Sbjct: 261 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 320 Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 AL+KAGL++ D+D+ E+NEAFA Q L L K N GGA+ALGHPLG +G+R Sbjct: 321 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR 380 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 L++EL+RRG + Y V S CIG G G A + + Sbjct: 381 ITAHLVHELRRRGGK-YAVGSACIGGGQGIAVIIQ 414 >5LP7-H nrPDB Length = 393 Score = 232 bits (592), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 151/393 (38%), Positives = 212/393 (53%), Gaps = 17/393 (4%) Query: 39 VVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGA 98 V+V RT + G G K+ EL VM L+ + + + +G V+Q G+G Sbjct: 5 VIVSAARTPFGKFG-GVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQAGSGQ 63 Query: 99 IMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR 158 I +R A L+ +P +VP T+N+ C+SGL+AV IR DI +A G+ESMS Sbjct: 64 IPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMSNIPY 123 Query: 159 GNPGNITSRLMEKEKARDCLIPMGIT-----------SENVAERFGISREKQDTFALASQ 207 P M + RD ++ G+T A+ + ISR +QD +AL S Sbjct: 124 AVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQDEWALRSH 183 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 267 +AA+A +G FQ EIVPV K V +DE IR T+++ LAKL P + D Sbjct: 184 ARAAKAADEGKFQDEIVPVNWIGRKGKPN----VVDKDEAIRRDTSLDQLAKLAPIYASD 239 Query: 268 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 327 GS TAGN+ V+DGA A +L KA ELG L + ++ G+P + P +AI Sbjct: 240 GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGFAINK 299 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 387 L+K GLTV D+D+FE+NEAFAS C + + EKVN GGA+ALGHP+G +GAR + Sbjct: 300 LLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASGARIL 359 Query: 388 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 +TL+ ELKRRG GV ++C G G A + + Sbjct: 360 MTLVYELKRRGG-GLGVAAICSGAAQGDAVLVQ 391 >5CBQ-A nrPDB Length = 413 Score = 230 bits (586), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 157/408 (38%), Positives = 219/408 (53%), Gaps = 28/408 (6%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ 93 S D V+ RT I R G G F+ T +L + +L+ + +Q+ D+ +G+ Sbjct: 8 SMRDAVICEPVRTPIGRYG-GMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCYP 66 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 + R+ + +P TVP V+R+C SGLQAV +R+G +D+ +A G ESM Sbjct: 67 NSEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESM 126 Query: 154 S-----LADRGNPGNITSRLMEKEKARDCL--------IPMGI--TSENVAERFGISREK 198 S D G T + AR +P G+ T+EN+ + ISR + Sbjct: 127 SNVAFYSTDMRWGGARTGVQIHDGLARGRTTAGGKFHPVPGGMLETAENLRREYHISRTE 186 Query: 199 QDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLA 258 QD A+ S Q+A AQS+G EI+PV D + T ++ DE R TT+E LA Sbjct: 187 QDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEET-----ISVDEHPRADTTVEALA 241 Query: 259 KLKPAFKK---DGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPD 315 KLKP K + + TAGNSS +D A+ ++ KA ELGL L L S+ GV PD Sbjct: 242 KLKPVLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPD 301 Query: 316 IMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRL---PPEKVNPLGGA 372 +MGIGP A VAL KAGLT++D+D+ E+NEAFA+QA + + + E+ N G Sbjct: 302 LMGIGPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSG 361 Query: 373 VALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 ++LGHP+G TG R + TL EL RR R YG+ +MCIG G G AAVFE Sbjct: 362 ISLGHPVGATGGRMLATLARELHRREAR-YGLETMCIGGGQGLAAVFE 408 >3SVK-A nrPDB Length = 407 Score = 214 bits (546), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 150/413 (36%), Positives = 213/413 (51%), Gaps = 32/413 (7%) Query: 31 PQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDV-NLRPEQLGDICVG 89 P + + + + RT + G + P L+ ++ + + +L + D+ +G Sbjct: 2 PGSMSEEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPDLDETLISDMILG 61 Query: 90 NVLQPG-AGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMAC 148 V G G +AR A + +PET +NR C+SGL+AV + A +R+G D+ +A Sbjct: 62 VVSPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAG 121 Query: 149 GVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQ 208 GVESMS G+ G + E R +P GI ++ +A G SRE D +AL SQQ Sbjct: 122 GVESMSRVPMGSDGGAWATDPET-NYRIGFVPQGIGADLIATLEGFSREDVDAYALRSQQ 180 Query: 209 KAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF---- 264 KAA A S G F +VPV D G + + DE +RP TTMEGLAKLK AF Sbjct: 181 KAAAAWSGGYFAKSVVPV----RDQNGL---VILDHDEHMRPDTTMEGLAKLKTAFDGVG 233 Query: 265 -----------------KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSY 307 K + T GNSS + DGAA +L+ + GL + + Sbjct: 234 EMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPRARIVAT 293 Query: 308 AVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVN 367 A G P IM GP A L +AGLT+ D+D+FE+NEAFAS + L +P EK+N Sbjct: 294 ATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIPDEKLN 353 Query: 368 PLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 GGA+A+GHPLG TGA T+++EL+RR R ++++CIG GMG A + E Sbjct: 354 VNGGAIAMGHPLGATGAMITGTMVDELERRNAR-RALITLCIGGGMGVATIIE 405 >6BN2-A nrPDB Length = 401 Score = 213 bits (543), Expect = 9e-56, Method: Compositional matrix adjust. Identities = 140/396 (35%), Positives = 220/396 (55%), Gaps = 20/396 (5%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 +V +V RT + + G +L + + L +NL P ++ D+ +GNVLQ G Sbjct: 11 EVFIVSAVRTPMG-SFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQDVYMGNVLQAGE 69 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G A+ A + +P T P + VN+ C+SG++AV A ++ G + +A G+E+MS Sbjct: 70 GQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMENMSQV 129 Query: 157 DRGNPGNITSRLMEKEKARDCLIPMGIT-----------SENVAERFGISREKQDTFALA 205 G +L + K +D L+ G+T +E A+ + I+RE+QD FA+ Sbjct: 130 PHYIDGRNGVKLGDI-KLQDGLLKDGLTDVYSKQHMGNCAELCAKEYNITREEQDAFAIQ 188 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 S +++A+A S+G F+ E+VPV+ + KG I +DE + + + + L F+ Sbjct: 189 SYERSAKAWSEGKFKEEVVPVS--IPQRKG--EPIIFAEDEEYK-NVKFDRIPTLPTVFQ 243 Query: 266 K-DGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYA 324 K +G+ TA N+S ++DGA+A++L + K E LGL L + SYA P+ PA A Sbjct: 244 KENGTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAPEWFTTAPAKA 303 Query: 325 IPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 +P+AL KA LT++D+D FE NEAF+ + L L KVN GGAVALGHPLG +G+ Sbjct: 304 LPIALAKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVALGHPLGSSGS 363 Query: 385 RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 R ++TL+N LK+ + YG ++C G G +A V E Sbjct: 364 RIIVTLINVLKQNNAK-YGAAAICNGGGGASAIVIE 398 >4B3J-C nrPDB Length = 403 Score = 207 bits (528), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 148/400 (37%), Positives = 209/400 (52%), Gaps = 34/400 (8%) Query: 45 RTAICRAGRGGFKDTTPDELLSAVMTAVLK-DVNLRPEQLGDICVGNVLQPG-AGAIMAR 102 RT + G + P L+ ++ + K +L + D+ +G V G G +AR Sbjct: 12 RTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLISDVILGCVSPVGDQGGDIAR 71 Query: 103 IAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPG 162 A S +P T +NR C+SGL+AV + A +R+G D+ +A GVESMS G+ G Sbjct: 72 AAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDG 131 Query: 163 NITSRLMEKEKARDCL-IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQA 221 ++ D + +P I ++ +A G SRE D +AL SQQKAA A S G F Sbjct: 132 GAMG--LDPATNYDVMFVPQSIGADLIATIEGFSREDVDAYALRSQQKAAEAWSGGYFAK 189 Query: 222 EIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF----------------- 264 +VPV D G + + DE +RP TT EGLAKLKPAF Sbjct: 190 SVVPV----RDQNGL---LILDHDEHMRPDTTKEGLAKLKPAFEGLAALGGFDDVALQKY 242 Query: 265 ----KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIG 320 K + T GNSS + DGAA +++ + + GL + + A G P IM G Sbjct: 243 HWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVATATSGADPVIMLTG 302 Query: 321 PAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLG 380 P A L +AGLTV D+D+FE+NEAFAS + L +P EK+N GGA+A+GHPLG Sbjct: 303 PTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLG 362 Query: 381 CTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 TGA + T+++EL+RR R ++++CIG GMG A + E Sbjct: 363 ATGAMILGTMVDELERRNAR-RALITLCIGGGMGVATIIE 401 >4UBW-A nrPDB Length = 399 Score = 207 bits (526), Expect = 9e-54, Method: Compositional matrix adjust. Identities = 145/395 (36%), Positives = 213/395 (53%), Gaps = 23/395 (5%) Query: 39 VVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGA 98 V+V R+ I + G ELL AV AV+ ++ + G+V Q G Sbjct: 13 VIVEATRSPIGKR-NGWLSGLHATELLGAVQKAVVDKAGIQS----GLHAGDVEQVIGGC 67 Query: 99 I---------MARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACG 149 + ++R+A + +PE V +TV+ QC SG QA IAG I G+ D+G+ACG Sbjct: 68 VTQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACG 127 Query: 150 VESMSLADRG-NPGNITSRLMEKEKARDCLIPMGI-TSENVAERFGISREKQDTFALASQ 207 +E+MS G N G R + + ++ D +P +E +A+R GI+RE D F L SQ Sbjct: 128 IEAMSRVGLGANAG--PDRSLIRAQSWDIDLPNQFEAAERIAKRRGITREDVDVFGLESQ 185 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKG--TKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 ++A RA ++G F EI P+ V D++ T V +D+G+R TTM GL +LKP + Sbjct: 186 RRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLR-ETTMAGLGELKPVLE 244 Query: 266 KDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 325 G TAG SSQ+SDGAAA+L + A GL + + A+VG P GP + Sbjct: 245 G-GIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDGPVQST 303 Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 L+KAG+ + D+DI EINEAFAS ++VN GGA+ALGHP+GCTG+R Sbjct: 304 AKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSR 363 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 + T L+EL+R ++ +++MC G + + E Sbjct: 364 LITTALHELERT-DQSLALITMCAGGALSTGTIIE 397 >5ZQZ-B nrPDB Length = 474 Score = 203 bits (516), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 153/433 (35%), Positives = 221/433 (51%), Gaps = 59/433 (13%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 +VVVV G RT +G +KD P +L A +T +L ++ E + I G V+Q Sbjct: 53 NVVVVDGVRTPFLLSGTS-YKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVK 111 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS-- 154 + +AR A + + P TV C S QA+ + G I +G D+ +A GVE MS Sbjct: 112 TSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDV 171 Query: 155 -----------LADRGNPGNITSRLMEKEKAR-DCLIP-------------MGITSENVA 189 + D ++ RL K R + L P MG +++ +A Sbjct: 172 PIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLA 231 Query: 190 ERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIR 249 F +SR +QD +AL S A +AQ +G +++VP D TVT+D GIR Sbjct: 232 AAFAVSRLEQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD--------TVTKDNGIR 282 Query: 250 PSTTMEGLAKLKPAF-KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYA 308 PS ++E +AKLKPAF K G+ TA NSS ++DGA+A+L+ KA +G LR + Sbjct: 283 PS-SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFM 341 Query: 309 VVGV-PPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQ---------AAYCVE- 357 V P D + +GP YA P L+KAGLT++D+D FE +EAF+ Q + + E Sbjct: 342 YVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAEN 401 Query: 358 ------KLRLPP-EKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIG 410 K+ LPP EK N GG+++LGHP G TG R V+ N L++ G + YG+V+ C Sbjct: 402 YMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQ-YGLVAACAA 460 Query: 411 TGMGAAAVFE-YP 422 G G A + E YP Sbjct: 461 GGQGHAMIVEAYP 473 >6BJA-A nrPDB Length = 397 Score = 188 bits (478), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 141/395 (35%), Positives = 211/395 (53%), Gaps = 20/395 (5%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DV ++ RT I + R + +L V +K L + + VGNVL G Sbjct: 10 DVYILSAVRTPIA-SFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAGL 68 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G +AR S+IP++ T+N+ CSS ++A+ A I+ G I +A G ESMS A Sbjct: 69 GQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSNA 128 Query: 157 DRGNP-GNITSRLMEKEKA--RDCLI------PMGITSENVAERFGISREKQDTFALASQ 207 P G I ++ A RD L+ PMG+ +E + + +RE+ D +A+ S Sbjct: 129 PFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQPMGLCAEKTVKDYAFTREQLDAYAIESY 188 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 267 +KA A +G F E+VPV+ V +G+K + +T+DE + E + L PAF KD Sbjct: 189 RKAEHAWKEGAFNKEVVPVS--VPQKRGSK--VVLTEDEEYK-RLIPEKVPALHPAFLKD 243 Query: 268 GS--TTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 325 GS TA N+S ++DGAAA +LA +E L + + SYA GV P + PA A+ Sbjct: 244 GSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALAV 303 Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 L ++GL + ++EINEAF+ +++LRL P++VN GGAVALGHPLG +GAR Sbjct: 304 KQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGAR 363 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 V+TL++ LK GV ++C G G +A + + Sbjct: 364 IVVTLVHALK---SDELGVAAICNGGGEASAILIK 395 >6ARG-A nrPDB Length = 399 Score = 186 bits (472), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 141/396 (35%), Positives = 206/396 (52%), Gaps = 19/396 (4%) Query: 38 VVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVN-LRPEQLGDICVGNVLQPGA 96 V +V RT + + G T +L + + A L V+ L+P + ++ GNV+ Sbjct: 8 VYIVSSARTPV-GSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANV 66 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G AR + + E+ +TVN+ C+SGL+A+ A I G+ D+ +A G ESMS A Sbjct: 67 GQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNA 126 Query: 157 DRGNPGNITSRLMEKEKARDCLIP-----------MGITSENVAERFGISREKQDTFALA 205 P T + D ++ MG+ +E A+ G SRE+QD +A+ Sbjct: 127 PHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEYAIR 186 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF- 264 + +KA AQ G F EI P+ + +G K +TVTQDE + + E L +KPAF Sbjct: 187 TYEKAQAAQKAGLFDEEIAPIQ--LPGFRG-KPDVTVTQDEEPK-NLNPEKLRAIKPAFI 242 Query: 265 KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYA 324 G+ TA NSS ++DGAAA++L +K +EL L + + + P PA A Sbjct: 243 PGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALA 302 Query: 325 IPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 IP AL+ AG+ +D FEINEAF+ A ++ L +P EKVN GGAVA+GHP+G +GA Sbjct: 303 IPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGA 362 Query: 385 RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 R + TLL LK + K G +C G G +A V E Sbjct: 363 RILTTLLGVLKAK-KGKLGCAGICNGGGGASALVVE 397 >6BJB-A nrPDB Length = 393 Score = 185 bits (469), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 130/368 (35%), Positives = 204/368 (55%), Gaps = 16/368 (4%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV V RT I + R F + L + LK+ N++P + + +G V+ A Sbjct: 9 DVVFVGAARTPI-GSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNA 67 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G AR + + ++ VN+ +SG++A+A A ++ ++ +A G+ESMS Sbjct: 68 GQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCV 127 Query: 157 DRGNP-GNIT---SRLME---KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQ 207 P G I ++L++ ++ D I MG ++ VA++F I+RE+QD +A+ S Sbjct: 128 PFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAILSY 187 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 267 +++A A +G F EI+P+ T +G K++ITV +DE + E + KLKPAF + Sbjct: 188 KRSAAAWKEGIFAKEIIPLEVT----QG-KKTITVEEDEEYK-KVNFEKIPKLKPAFTSE 241 Query: 268 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 327 GS TA N+S ++DGAA +++ A++ GL L + +Y P GI PA IP Sbjct: 242 GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPK 301 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 387 L+ AGL + D+D++EINEAFA Y ++ L L KVN GGAV+LGHP+G +GAR V Sbjct: 302 VLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIV 361 Query: 388 ITLLNELK 395 L++ LK Sbjct: 362 GHLVHTLK 369 >5XYJ-B nrPDB Length = 408 Score = 184 bits (468), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 138/403 (34%), Positives = 211/403 (52%), Gaps = 29/403 (7%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPE-----QLGDICVGNV 91 +V +V RT I + +G T EL + + L V PE +I GNV Sbjct: 14 NVYIVSTARTPIG-SFQGSLSSKTAVELGAVALKGALAKV---PELDASKDFDEIIFGNV 69 Query: 92 LQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 L G AR + + + STVN+ +S ++A+ A I+ G+ D+ +A G E Sbjct: 70 LSANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGCE 129 Query: 152 SMSLADRGNPG---------NITSRLMEKEKARDCL--IPMGITSENVAERFGISREKQD 200 SM+ A P + +E++ D + MG+ +E A + I+RE+QD Sbjct: 130 SMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQD 189 Query: 201 TFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPS-TTMEGLAK 259 FA+ S QK+ ++Q +G F EIVPVT + +G K VT+DE P+ +E L Sbjct: 190 NFAIESYQKSQKSQKEGKFDNEIVPVT--IKGFRG-KPDTQVTKDE--EPARLHVEKLRS 244 Query: 260 LKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMG 318 + F+K+ G+ TA N+S ++DGAAA++L +E L L +++ + P Sbjct: 245 ARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFT 304 Query: 319 IGPAYAIPVALQKAGLT-VSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGH 377 P+ A+P AL+ AG+ ++ VD FE NEAF+ + L+L P KVN GGAVALGH Sbjct: 305 WAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGH 364 Query: 378 PLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 PLGC+GAR V+TLL+ L++ G + GV ++C G G ++ V E Sbjct: 365 PLGCSGARVVVTLLSILQQEGGK-IGVAAICNGGGGASSIVIE 406 >2IBU-A nrPDB Length = 395 Score = 181 bits (460), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 133/400 (33%), Positives = 216/400 (54%), Gaps = 20/400 (5%) Query: 30 APQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVG 89 A + + +VV+V RT I + G +L S + ++ + E++ + +G Sbjct: 2 ASKPTLKEVVIVSATRTPIG-SFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMG 60 Query: 90 NVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACG 149 NVLQ G G R A + +P + P +T+N+ C+SG++A+ + + G D+ +A G Sbjct: 61 NVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGG 120 Query: 150 VESMS----LADRGNP---GNITSRLMEKEKARDCL--IPMGITSENVAERFGISREKQD 200 +ESMS + +RG+ G L+ K+ D I MG +EN A++ I+R +QD Sbjct: 121 MESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQD 180 Query: 201 TFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKL 260 +A+ S ++ A G F E++PVT TV KG + + V +DE + + KL Sbjct: 181 AYAINSYTRSKAAWEAGKFGNEVIPVTVTV---KG-QPDVVVKEDEEYK-RVDFSKVPKL 235 Query: 261 KPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGI 319 K F+K+ G+ TA N+S ++DGAAA++L A+ L + L + ++A V P I Sbjct: 236 KTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPI 295 Query: 320 GPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPL 379 P YA + L+ GL D+ ++E+NEAF+ ++ L + P+KVN GGAV+LGHP+ Sbjct: 296 APVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPI 355 Query: 380 GCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVF 419 G +GAR V L + LK+ YG+ S+C G G GA+A+ Sbjct: 356 GMSGARIVGHLTHALKQ---GEYGLASICNGGG-GASAML 391 >6ESQ-A nrPDB Length = 392 Score = 61.6 bits (148), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 91/413 (22%), Positives = 160/413 (38%), Gaps = 78/413 (18%) Query: 44 RRTAICRAGRGGFKDTTPDELLSAVMTA---VLKDVNLRPEQLGDICVGNVLQPGAGAIM 100 R AI G+ F + D ++ A +KD N+ + + +GN + G Sbjct: 2 RDVAIIGYGQTKFGELWEDSFRDLIVEAGVKAIKDANVDGGDIDAMYIGN-MSGGLFVGQ 60 Query: 101 ARIAQFLSDIP--ETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR 158 IA ++D VP + V C+SG A+ S + +G +D+ +A GVE M+ + Sbjct: 61 EHIASLIADHAGLNPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAGGVEKMTDVED 120 Query: 159 GNPGNITSRLMEKEKARDCLIP--MGITSENVAERFGISREKQDTFALASQQKAARAQSK 216 ++ E E P + + ++G++ E+ +++ + + A + Sbjct: 121 ATAAIASASDQEWEAFFGATFPSLYAMMARRYMYQYGLTIEELSMWSVIAHENATK---- 176 Query: 217 GCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSS 276 +K + T ++ + S + L T + S Sbjct: 177 ----------------NKYAQFGFKTTLEQVMNASPVADPL-------------TLMHCS 207 Query: 277 QVSDGAAAILLARRSKAEELG-----LPILGVLRSYAVVGVP--PDIMGIGPA-YAIPVA 328 VSDGA+A+++ KAEE + I ++ + + D+ + A A A Sbjct: 208 PVSDGASALIVCDADKAEEFAPKDEIIYIKASTQASDTIALHDREDMTTLNAAKVASEKA 267 Query: 329 LQKAGLTVSDVDIFEINEAFASQAAYCVE-----------------KLRLPPEK---VNP 368 + A + +D+ E+++ FA VE K+R+ + VNP Sbjct: 268 YKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFCKKGDAGKVIDEGKIRIDYDDFVTVNP 327 Query: 369 LGGAVALGHPLGCTGARQVITLLNELKRRG---------KRAYGVVSMCIGTG 412 GG A GH LG TG RQV L +LK+ K YG+ + GTG Sbjct: 328 SGGLKAAGHALGATGIRQVGELYWQLKQDKECKDRQATIKNGYGIAANVGGTG 380 >6HRV-A nrPDB Length = 421 Score = 54.3 bits (129), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 81/354 (22%), Positives = 138/354 (38%), Gaps = 58/354 (16%) Query: 73 LKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVAS 132 L D ++ + CVG V + + A + S +P+ VN CS+G A+ Sbjct: 48 LADAGIKYSAIQQACVGYVY---GDSTCGQRAIYHSLGLSGIPIINVNNNCSTGSTALFM 104 Query: 133 IAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERF 192 I+ G D +A G E M G+++S+ M++ PM E + R+ Sbjct: 105 GRQLIQGGLADCVLALGFEKME------RGSLSSKYMDRTN------PMDKHMEVMINRY 152 Query: 193 GISR--EKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRP 250 G++ F A ++ + +K E + T + QDE Sbjct: 153 GLAAVPAAPQMFGNAGREHMEKYGTK----PEHFAKVAWKNHKHSTNNPYSQFQDE---- 204 Query: 251 STTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLA-----RRSKAEELGLPILG--V 303 ++E + + F+ T SDGA A +LA RR+ E+ + I+ + Sbjct: 205 -YSLEQVIDSRKVFE---FLTLLQCCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEM 260 Query: 304 LRSYAVVGVPPDIMGIGPAYAIPVALQK----AGLTVSDVDIFEINEAFASQAAYCVEKL 359 + + M + +A ++ AG+ SDVD+ E+++ F++ E L Sbjct: 261 VTDLSTTFEENSCMKMVGYDMTRLAAERCYDTAGVKPSDVDVIELHDCFSANELITYEAL 320 Query: 360 RLPPEK------------------VNPLGGAVALGHPLGCTGARQVITLLNELK 395 L PE +NP GG ++ GHPLG TG Q L +L+ Sbjct: 321 GLCPEGKAGELIDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLR 374 >5LNQ-A nrPDB Length = 457 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 59/316 (18%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKA 174 P V +SG AV S +++GS DI +A GVE + A G+ +R + ++ Sbjct: 131 PAMRVEGAAASGGLAVISAMNALKSGSADITLAVGVEVQTTASARVGGDYLARAADYQRQ 190 Query: 175 R---DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVH 231 R D P A+R E + F + + AR +K P+ +H Sbjct: 191 RQLDDFTFPCLF-----AKRMKYIAE-HNHFTM---EDTARVAAKAYANGNKNPLAH-MH 240 Query: 232 DDKGTKRSITVTQDEGIRPSTT-MEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARR 290 R +T Q G PS G K + + SQVSDG A ++LA Sbjct: 241 -----TRKLTFEQCNGEDPSNVKFLGNETYKEYLRMT------DCSQVSDGGAGVVLANE 289 Query: 291 SKAEELGLP--------ILGVLRSYAVVGVPPD--IMGIGPAYAIPVALQKAGLTVSDVD 340 ++GL I + + + + PD A AL A + SD++ Sbjct: 290 EGLRKMGLSPNDSRLVEIKSIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPSDLN 349 Query: 341 IFEINEAFASQAAYCVEKL---------------------RLPPEKVNPLGGAVALGHPL 379 + E+++ F E L R+P VN GG ++ GHP+ Sbjct: 350 VAEVHDCFTIAEMLMYEALGIAEYGHAKDLIRNGDTTLEGRIP---VNTGGGLLSFGHPV 406 Query: 380 GCTGARQVITLLNELK 395 G TG +Q++ + ++K Sbjct: 407 GATGIKQIMEVYRQMK 422 >4BI9-A nrPDB Length = 454 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 108/444 (24%), Positives = 166/444 (37%), Gaps = 97/444 (21%) Query: 17 SGWMPQAAPCLS-GAPQASAADVVVVHGRRTAICRAGRGGFKDT-----------TPDEL 64 SG +P+ + L + SA V VV G T G F D T +EL Sbjct: 8 SGLVPRGSHMLRRTSSTFSAKRVFVVGGHITTFVGKGSPLFIDKKHPDFGKKENKTLEEL 67 Query: 65 LSAVMTAVLKDVNL---RPEQLGDICVGNVL------QPGAG-AIMARIAQFLSDIPETV 114 L+ + L++ L R + + VGN L Q G A + ++ S Sbjct: 68 LAESINGALQNTGLHDGRAALVDKLVVGNFLGELFSSQGHLGPAAVGSLSGSNSSAFLNK 127 Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKA 174 P V C+SG AV S + G+ I +A GVE + +++R+ A Sbjct: 128 PAVRVEGACASGGLAVQSAWEALLAGTSQIALAVGVEVQT--------TVSARVGGDYLA 179 Query: 175 RDCLIPMGITSENVAERFGISREKQD-TFALASQQKAARAQSKGCFQAEIVPVTTTVHDD 233 R A + R+ D TF ++ Q G F E Sbjct: 180 R-------------AAHYKRQRQLDDFTFPCLFARRMKAIQEAGHFTMEDAAYVAAKAYA 226 Query: 234 KGTK--------RSITV---TQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGA 282 G + R +T+ TQ P+ G KP + TT + SQVSDG Sbjct: 227 SGNRNPLAHMHARKVTLDFCTQASDKNPN--FLGNEIYKPFLR----TT--DCSQVSDGG 278 Query: 283 AAILLARRSKAEELGLP----ILGVLRSYA-----VVGVPPDIMGIGPAY-AIPVALQKA 332 AA++LA ++LGL L ++S A + PD+ + + A AL A Sbjct: 279 AAVILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMVAARTALSMA 338 Query: 333 GLTVSDVDIFEINEAFASQAAYCVEKL---------------------RLPPEKVNPLGG 371 G+ + + E+++ F E L R+P VN GG Sbjct: 339 GVKPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIRSGATALDGRIP---VNTGGG 395 Query: 372 AVALGHPLGCTGARQVITLLNELK 395 ++ GHP+G TG +QV+ + ++K Sbjct: 396 LLSFGHPVGATGVKQVLEVYRQMK 419 >5M3K-C nrPDB Length = 398 Score = 32.3 bits (72), Expect = 0.38, Method: Compositional matrix adjust. Identities = 76/371 (20%), Positives = 127/371 (34%), Gaps = 65/371 (17%) Query: 60 TPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ--PGAGAIMARIAQFLSDIPETVPLS 117 T E++ LKD + P ++ + G + G + I+ L P +S Sbjct: 25 TFKEMIVESAYKALKDAKMHPREIQAVAYGYHGEGISEYGGLGPTISDALGISPAPTFMS 84 Query: 118 TVNRQCSS-----GLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKE 172 T N SS G Q VAS G YDI + G E M+ D N E E Sbjct: 85 TANCTSSSVSFQMGHQMVAS-------GEYDIVLCGGFEKMT--DHFNYAEYIGSSTECE 135 Query: 173 KARDCLIP----MGITSENVAERFGISREKQDTFALASQQKAARAQSK--GCFQAEIVPV 226 I + + ++FG + + D A +Q AQ+ + +P Sbjct: 136 YDYFLGISHTDAFALATAEYFQKFGYAGREADVLATFGRQMRIYAQNTPTATRYGQPIPS 195 Query: 227 TTTVHDDKGTKRSITVTQDEG--IRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAA 284 + + + + + G I + + KP F + + T + Sbjct: 196 LEVLKNSEACGSMLAWGEASGCAILVAEHLAHKYTDKPVFVRGCAYTG----------VS 245 Query: 285 ILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI---PVALQKAGLTVSDVDI 341 R L P G+P D+ A +I +A +KAG+T D+D+ Sbjct: 246 HYFGTRFHNPTLHHP-----------GLPKDVGMAVSANSIACAEIAYKKAGITAKDIDV 294 Query: 342 FEINEAFAS--------------QAAYCVEKLRLPPEKVNPL---GGAVALGHPLGCTGA 384 ++ + + QA V + + + PL GG + GH GC G Sbjct: 295 AQVYDLLGAGLIQMESMGICGKGQAGDFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGI 354 Query: 385 RQVITLLNELK 395 + L +L+ Sbjct: 355 LHITELFRQLR 365 >4YZO-A nrPDB Length = 373 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 10/32 (31%), Positives = 19/32 (59%) Query: 366 VNPLGGAVALGHPLGCTGARQVITLLNELKRR 397 +NP GG + GHP+G +G Q + ++++ Sbjct: 309 INPSGGLNSKGHPIGASGVAQAVEAFSQIRNE 340 >1X1P-A nrPDB Length = 212 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 19/28 (67%) Query: 291 SKAEELGLPILGVLRSYAVVGVPPDIMG 318 + E+L ILGVL Y ++ +PPD++G Sbjct: 47 KRREKLFNEILGVLDDYVILELPPDVIG 74 >2GP6-A nrPDB Length = 434 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 20/130 (15%) Query: 280 DGAAAILLARRSKAEELGLPILGVLRSYAVVG-----VPPDIMGIGPAYAIPVALQKAGL 334 +G A +L+ A+ G IL + ++ V PD G +AI A+Q AGL Sbjct: 258 EGGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGL 317 Query: 335 TVSDVDIFEIN-EAFASQAAYCVEKLRLPPEKVNPLGG--------AVALGHPLGCTGAR 385 D+D +N A +Q E + N LGG ALGH +G GA Sbjct: 318 APGDID--HVNAHATGTQVGDLAEGRAIN----NALGGNRPAVYAPKSALGHSVGAVGAV 371 Query: 386 QVITLLNELK 395 + I + L+ Sbjct: 372 ESILTVLALR 381 >1J3N-A nrPDB Length = 408 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 32/134 (23%) Query: 73 LKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQ---FLSDIPETV--------------- 114 L+D L+PE L VG ++ G G + AQ FL P + Sbjct: 83 LEDAGLKPEDLDPERVGTLVGTGIGGMETWEAQSRVFLERGPNRISPFFIPMMIANMASA 142 Query: 115 ----------PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES----MSLADRGN 160 P STV C++G A+ S I+ G D+ +A G E+ M++ Sbjct: 143 HIAMRYGFTGPSSTVVTACATGADALGSALRMIQLGEADLVLAGGTEAAITPMAIGAFAV 202 Query: 161 PGNITSRLMEKEKA 174 +++R E EKA Sbjct: 203 MRALSTRNEEPEKA 216 >4JD3-A nrPDB Length = 353 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 34/87 (39%) Query: 69 MTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQ 128 + L D NLRP + I V ++ ARIA L P+ + +G Sbjct: 84 LLGALDDANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPDVRRMPLFGLGSVAGAA 143 Query: 129 AVASIAGGIRNGSYDIGMACGVESMSL 155 VA + +R D+ + VE SL Sbjct: 144 GVARLRDYLRGAPDDVAVLVSVELCSL 170 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2IIK-A nrPDB 549 e-157 4N44-A nrPDB 494 e-140 4E1L-A nrPDB 480 e-136 4DD5-A nrPDB 474 e-134 2C7Y-A nrPDB 472 e-133 2WUA-A nrPDB 468 e-132 3SS6-A nrPDB 460 e-130 1NL7-A nrPDB 454 e-128 4O9A-A nrPDB 449 e-126 4C2K-A nrPDB 448 e-126 1WL4-A nrPDB 446 e-125 1ULQ-A nrPDB 444 e-125 6BN2-A nrPDB 443 e-125 2IBU-A nrPDB 437 e-123 4WYS-A nrPDB 437 e-123 4NZS-A nrPDB 434 e-122 5LP7-H nrPDB 431 e-121 1PXT-A nrPDB 428 e-120 6ARG-A nrPDB 422 e-118 1WDK-C nrPDB 421 e-118 3GOA-A nrPDB 420 e-118 3SVK-A nrPDB 418 e-117 5CBQ-A nrPDB 417 e-117 5XYJ-B nrPDB 411 e-115 6BJA-A nrPDB 406 e-113 4B3J-C nrPDB 403 e-113 6BJB-A nrPDB 401 e-112 5ZQZ-B nrPDB 376 e-105 4UBW-A nrPDB 373 e-104 6ESQ-A nrPDB 257 5e-69 4BI9-A nrPDB 255 3e-68 6HRV-A nrPDB 248 4e-66 5LNQ-A nrPDB 247 8e-66 Sequences not found previously or not previously below threshold: 4YZO-A nrPDB 114 8e-26 5M3K-C nrPDB 87 1e-17 4U4E-A nrPDB 77 1e-14 5AB6-A nrPDB 62 6e-10 4EWP-A nrPDB 52 7e-07 3O04-A nrPDB 50 1e-06 4QAV-A nrPDB 47 1e-05 4R8E-A nrPDB 47 2e-05 2GP6-A nrPDB 46 2e-05 1J3N-A nrPDB 46 2e-05 5W2O-A nrPDB 46 3e-05 3E60-A nrPDB 46 3e-05 4DFE-A nrPDB 45 6e-05 3KZU-A nrPDB 45 6e-05 2IX4-A nrPDB 45 7e-05 4LS7-A nrPDB 44 1e-04 2EBD-A nrPDB 44 1e-04 4X0O-A nrPDB 44 2e-04 1OXH-A nrPDB 43 2e-04 4JPF-A nrPDB 43 2e-04 4YUC-A nrPDB 43 2e-04 5BY7-A nrPDB 43 3e-04 2GQD-A nrPDB 43 3e-04 4DDO-A nrPDB 43 3e-04 6QSP-A nrPDB 42 4e-04 4JGA-A nrPDB 42 5e-04 4RYB-A nrPDB 41 7e-04 1MZJ-A nrPDB 41 0.001 4JRH-A nrPDB 40 0.001 4V2P-A nrPDB 40 0.002 4NHD-A nrPDB 40 0.002 3H76-A nrPDB 40 0.003 6ESQ-I nrPDB 38 0.006 3IL7-A nrPDB 38 0.008 3HO9-A nrPDB 38 0.010 4YLT-A nrPDB 37 0.013 2AJ9-A nrPDB 37 0.013 5BQS-A nrPDB 37 0.014 1UB7-A nrPDB 37 0.016 4JD3-A nrPDB 37 0.017 3IL4-A nrPDB 36 0.023 2IWZ-A nrPDB 36 0.024 5ENY-A nrPDB 36 0.029 6ET0-A nrPDB 35 0.067 4XOX-A nrPDB 35 0.071 5BNS-A nrPDB 35 0.082 4EFI-A nrPDB 34 0.11 1TQY-A nrPDB 34 0.11 4OQJ-A nrPDB 34 0.12 5YO9-A nrPDB 34 0.13 3UBR-A nrPDB 33 0.23 1E5M-A nrPDB 33 0.26 5L9W-B nrPDB 33 0.31 5GW4-d nrPDB 33 0.36 2P1R-A nrPDB 32 0.38 2BZ4-A nrPDB 32 0.43 3GGO-A nrPDB 32 0.51 1TQY-B nrPDB 31 0.81 6CTD-A nrPDB 31 0.97 5LBT-A nrPDB 31 1.2 6G2J-R nrPDB 30 1.6 5MB9-A nrPDB 30 1.7 5VXG-A nrPDB 30 1.7 4ZCK-A nrPDB 30 2.0 4JN4-A nrPDB 30 2.0 3OYT-A nrPDB 30 2.1 2Z0I-A nrPDB 30 2.3 5XTD-T nrPDB 30 2.4 2IVO-A nrPDB 30 2.6 5O31-R nrPDB 30 3.0 5GUP-F nrPDB 29 3.7 5LNM-A nrPDB 29 3.9 4IEI-A nrPDB 29 4.0 3U0E-A nrPDB 29 4.4 6IOX-A nrPDB 29 4.7 4TLZ-A nrPDB 28 6.0 4ANI-C nrPDB 28 6.2 5ODO-A nrPDB 28 6.5 2D0P-A nrPDB 28 6.5 3P1L-A nrPDB 28 6.6 4RQ9-A nrPDB 28 6.6 1W2A-X nrPDB 28 6.8 1DXL-A nrPDB 28 7.0 6ET3-B nrPDB 28 7.1 5LVW-A nrPDB 28 7.3 4OXP-A nrPDB 28 7.4 3T5Y-A nrPDB 28 8.4 4OH7-A nrPDB 28 8.7 3OA3-A nrPDB 28 9.2 5TNV-A nrPDB 28 9.3 3VEW-A nrPDB 28 9.3 2X3E-A nrPDB 28 10.0 >2IIK-A nrPDB Length = 418 Score = 549 bits (1415), Expect = e-157, Method: Composition-based stats. Identities = 396/397 (99%), Positives = 396/397 (99%) Query: 28 SGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC 87 S APQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC Sbjct: 22 SMAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC 81 Query: 88 VGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMA 147 VGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMA Sbjct: 82 VGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMA 141 Query: 148 CGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQ 207 CGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQ Sbjct: 142 CGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQ 201 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 267 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD Sbjct: 202 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 261 Query: 268 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 327 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV Sbjct: 262 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 321 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 387 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV Sbjct: 322 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 381 Query: 388 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN 424 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN Sbjct: 382 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN 418 >4N44-A nrPDB Length = 400 Score = 494 bits (1271), Expect = e-140, Method: Composition-based stats. Identities = 167/397 (42%), Positives = 235/397 (59%), Gaps = 18/397 (4%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 +VV+ RTAI G+ KD +L + + +K ++PE + ++ +GNVLQ Sbjct: 1 MKEVVIASAVRTAIGSYGK-SLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQA 59 Query: 95 GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS 154 G G AR A F + +P +P T+N+ C SGL+ V+ A I+ G D+ +A G+E+MS Sbjct: 60 GLGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMS 119 Query: 155 LADRGNPGNITSRLMEKEKARDCLI-----------PMGITSENVAERFGISREKQDTFA 203 A M K D +I MGIT+EN+AER+ ISRE+QD FA Sbjct: 120 RAPYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFA 179 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 LASQ+KA A G F+ EIVPV KG K V DE R +T+EGLAKLKPA Sbjct: 180 LASQKKAEEAIKSGQFKDEIVPVVI-----KGRKGETVVDTDEHPRFGSTIEGLAKLKPA 234 Query: 264 FKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 FKKDG+ TAGN+S ++D AA +++ KA+ELG+ L + SY GV P IMG GP Y Sbjct: 235 FKKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFY 294 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 A A++KAG TV ++D+ E NEAFA+Q+ + L+ KVN GGA+ALGHP+G +G Sbjct: 295 ATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASG 354 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 AR ++TL++ +++R + G+ ++CIG G G A + E Sbjct: 355 ARILVTLVHAMQKRDAKK-GLATLCIGGGQGTAILLE 390 >4E1L-A nrPDB Length = 395 Score = 480 bits (1237), Expect = e-136, Method: Composition-based stats. Identities = 164/397 (41%), Positives = 234/397 (58%), Gaps = 17/397 (4%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ 93 + DVV+V RT I G G FK+T+ +L + + + V L ++ ++ +GNVLQ Sbjct: 3 AMKDVVIVSAVRTPIGSFG-GVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQ 61 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G G +AR + IP +VP TVN+ C SGL++V A I +G D+ +A G E+M Sbjct: 62 TGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENM 121 Query: 154 SLADRGNPGNITSRLME-----KEKARDCLI------PMGITSENVAERFGISREKQDTF 202 S A P M D LI MGIT+EN+A +F +RE QD Sbjct: 122 SQAPYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQDKL 181 Query: 203 ALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKP 262 AL SQ KA A F+ EIVPV + K T+ +DE + T EGL+KLKP Sbjct: 182 ALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIE----TIDKDEYPKLGMTFEGLSKLKP 237 Query: 263 AFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPA 322 AFKKDG+ TAGN+S ++DGAA ++L + KA+ELG+ L ++SYA GV P++MG GP Sbjct: 238 AFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPI 297 Query: 323 YAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCT 382 A AL+KAGL+++D+D+ E NEAFA+QA +L++ K+N GGA+ALGHP+G + Sbjct: 298 PATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGAS 357 Query: 383 GARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVF 419 GAR ++TL+ E+++R K G+ ++CIG G G + V Sbjct: 358 GARILVTLIYEMQKR-KVETGLATLCIGGGQGISMVV 393 >4DD5-A nrPDB Length = 396 Score = 474 bits (1221), Expect = e-134, Method: Composition-based stats. Identities = 165/397 (41%), Positives = 230/397 (57%), Gaps = 18/397 (4%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 +VV+ RTA+ G G FK + EL +K N+ P+ + + +G VL Sbjct: 6 MREVVIASAARTAVGSFG-GAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTA 64 Query: 95 GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS 154 G G +AR + IP P T+N C SGL++V+ + I G DI + G E+MS Sbjct: 65 GLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMS 124 Query: 155 LADRGNPGNITSRLMEKEKARDCLI-----------PMGITSENVAERFGISREKQDTFA 203 ++ P M D +I MGIT+EN+AE++ I+RE+QD A Sbjct: 125 MSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNITREEQDELA 184 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 LASQ KA +AQ++G F EIVPV KG K V +DE I+P TTME LAKL+PA Sbjct: 185 LASQNKAEKAQAEGKFDEEIVPVVI-----KGRKGDTVVDKDEYIKPGTTMEKLAKLRPA 239 Query: 264 FKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 FKKDG+ TAGN+S ++DGAA +++ + KAEELG+ L + SY GV P IMG GP Sbjct: 240 FKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPVP 299 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 A AL+ A +T+ D+D+ E NEAFA+Q+ + L + KVN GGA+A+GHP+GC+G Sbjct: 300 ATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCSG 359 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 AR + TLL E+KRR + G+ ++CIG GMG + + Sbjct: 360 ARILTTLLYEMKRRDAKT-GLATLCIGGGMGTTLIVK 395 >2C7Y-A nrPDB Length = 404 Score = 472 bits (1216), Expect = e-133, Method: Composition-based stats. Identities = 227/387 (58%), Positives = 291/387 (75%), Gaps = 3/387 (0%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV+V RT +C++ RG FKDT PD+LL+ V+ A+++ NL P ++GDI VG VL PG+ Sbjct: 14 DVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGS 73 Query: 97 G-AIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155 A R+A F + PETV + TVNRQCSSGLQAVA +A I+ G YDIG+ G+ESM+ Sbjct: 74 QRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTT 133 Query: 156 ADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQS 215 G++ + + +A++CL+PMG+TSENVA+RFG+SR++QD A+ S +KAA A + Sbjct: 134 NPMAWEGSVNPAVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAAVDSHRKAAAATA 193 Query: 216 KGCFQAEIVPVTTTVHDDK-GTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGN 274 G F+ EI+PV T + D K G ++ ITV+ D+GIRP+TT+ L KLKP FKKDG+TTAGN Sbjct: 194 AGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKPVFKKDGTTTAGN 253 Query: 275 SSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGL 334 SSQVSDGA A+LL +RS A + GLP+LGV R++A VGV P IMGIGPA AIP A++ AGL Sbjct: 254 SSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGPAVAIPAAVKAAGL 313 Query: 335 TVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNEL 394 + D+D+FEINEAFASQ YC KL L PEK+N GGA+A+GHPLG TGAR V TLL+E+ Sbjct: 314 ELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGARCVATLLHEM 373 Query: 395 KRRGKRA-YGVVSMCIGTGMGAAAVFE 420 KRRGK +GVVSMCIGTGMGAAAVFE Sbjct: 374 KRRGKDCRFGVVSMCIGTGMGAAAVFE 400 >2WUA-A nrPDB Length = 440 Score = 468 bits (1205), Expect = e-132, Method: Composition-based stats. Identities = 219/387 (56%), Positives = 291/387 (75%), Gaps = 3/387 (0%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV+V R+ +C+A RGG KDT PD++L+ V+ A+++ N+ P ++GDI VG+VL G+ Sbjct: 34 DVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVLGAGS 93 Query: 97 G-AIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155 A R+A F + PETVP+ TVNRQCSSGLQAVA +A I+ G YDIG+ G+ESM+ Sbjct: 94 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTA 153 Query: 156 ADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQS 215 G++ ++ +A+DCL+PMGITSENVA++F I+R++QD A+ S +K A A + Sbjct: 154 NPMAWEGSVNPKVKTMAQAQDCLLPMGITSENVAQKFSITRQEQDQAAVGSHRKTAAATA 213 Query: 216 KGCFQAEIVPVTTTVHDDK-GTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGN 274 G F+ EI+P+ T + D K G ++ +T++ D+GIRP T++ LAKLKP F+KDGSTTAG Sbjct: 214 AGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDGIRPGTSLADLAKLKPVFRKDGSTTAGT 273 Query: 275 SSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGL 334 SSQVSDGA A+LL +RS A + GLPILGV R++A VGVPP IMGIGPA AIP A++ AGL Sbjct: 274 SSQVSDGAGAVLLMKRSIALQKGLPILGVFRTFAAVGVPPSIMGIGPAVAIPAAVKAAGL 333 Query: 335 TVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNEL 394 + D+D+FEINEAFASQ YC +KL + P+K+N GGA+A+GHPLG TGAR V TLL+E+ Sbjct: 334 QIDDIDLFEINEAFASQFVYCQKKLEIDPQKINVNGGAMAIGHPLGATGARCVATLLHEM 393 Query: 395 KRRGKRA-YGVVSMCIGTGMGAAAVFE 420 KRRG+ +GVVSMCIGTGMGAAAVFE Sbjct: 394 KRRGRDCRFGVVSMCIGTGMGAAAVFE 420 >3SS6-A nrPDB Length = 394 Score = 460 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 158/397 (39%), Positives = 229/397 (57%), Gaps = 17/397 (4%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ 93 + +VV+ R+ I G G K+ TP EL V+ +K + P ++ ++ +G+ +Q Sbjct: 3 AMHNVVITAAVRSPIGTFG-GALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQ 61 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 A AR A + P+TV T+ RQCSSG+QA+ S A I+ G ++ +A GVE+M Sbjct: 62 RTDEANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAM 121 Query: 154 SLADRGNPGNITSRLMEKEKARD----------CLIPMGITSENVAERFGISREKQDTFA 203 S + + + ++ + RD I MG T+EN+ E++ I+RE+QD A Sbjct: 122 SSSPYALKQHRWGQRLQHGEIRDTVWEVLEDPIHHIMMGETAENLVEQYEITREEQDEVA 181 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 L S A +A G F +IVP+T K ++ + ++DE R T E LA LKPA Sbjct: 182 LRSHTLALKAIESGYFDDQIVPITI-----KERRKEVVFSKDEHPRADITAEKLAGLKPA 236 Query: 264 FKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 F+KDGS TAGN+S ++DG+A ++L KA+E GL L + Y+V GV P IMGIGPA Sbjct: 237 FRKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAP 296 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 AI L+K ++ D D+ EINEAFA+Q ++L L EKVN G V LGHP+GCTG Sbjct: 297 AIRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPIGCTG 356 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 AR ++L++ELKRRG G+ S+C+G G+G A E Sbjct: 357 ARITVSLIHELKRRGLEK-GIASLCVGGGIGVALFIE 392 >1NL7-A nrPDB Length = 392 Score = 454 bits (1168), Expect = e-128, Method: Composition-based stats. Identities = 163/397 (41%), Positives = 229/397 (57%), Gaps = 17/397 (4%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ 93 S +V+ RTA+ + G F +T EL + V++AVL+ + ++ ++ +G VL Sbjct: 1 STPSIVIASAARTAVG-SFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLP 59 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G G AR A + +P+ +N+ C SGL+AVA I G I +A G+ESM Sbjct: 60 AGEGQNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESM 119 Query: 154 SLADR----GNPGNITSRLMEKEKARDCL------IPMGITSENVAERFGISREKQDTFA 203 S+A + M +D L MG T+ENVA+++ +SR++QD FA Sbjct: 120 SMAPHCAHLRGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFA 179 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 +ASQ KA AQ G F+ EIVP KG K ITV DE IR T++ +AKL+PA Sbjct: 180 VASQNKAEAAQKDGRFKDEIVPFIV-----KGRKGDITVDADEYIRHGATLDSMAKLRPA 234 Query: 264 FKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 F K+G+ TAGN+S ++DGAAA LL ++A G+ LG + S+A VGV P +MG GP Sbjct: 235 FDKEGTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIP 294 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 A AL++AG + D+D+ E NEAFA+QA + L P VN GGA+A+GHP+G +G Sbjct: 295 ASRKALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASG 354 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 AR + TLL E+KRRG R G+ ++CIG GMG A E Sbjct: 355 ARILNTLLFEMKRRGARK-GLATLCIGGGMGVAMCIE 390 >4O9A-A nrPDB Length = 398 Score = 449 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 163/395 (41%), Positives = 228/395 (57%), Gaps = 17/395 (4%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV+V RTA+ + G G EL + V+ A L+ ++PEQ+ ++ +G VL G+ Sbjct: 8 DVVIVSAARTAVGKFG-GSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGS 66 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G AR A + +P VP T+N+ SGL+AV A I G +I +A G E+MS A Sbjct: 67 GQNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAA 126 Query: 157 DRGNPGNITSRLMEKEKARDCLI-----------PMGITSENVAERFGISREKQDTFALA 205 PG+ M K D +I MGIT+ENVA+ +GI+RE QD FA+ Sbjct: 127 PHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVG 186 Query: 206 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 265 SQ KA AQ G F EIVPV + DE +R T++ ++ LKPAF Sbjct: 187 SQNKAEAAQKAGKFDEEIVPVLIPQRKGD----PVAFKTDEFVRQGATLDSMSGLKPAFD 242 Query: 266 KDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 325 K G+ TA N+S ++DGAAA+++ +KA+ELGL L ++SYA GV P +MG+GP A Sbjct: 243 KAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPAS 302 Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 AL +A T D+D+ EINEAFA+QA +++ KVN GGA+A+GHP+G +G R Sbjct: 303 KRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCR 362 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 ++TLL+E+KRR + G+ S+CIG GMG A E Sbjct: 363 ILVTLLHEMKRRDAKK-GLASLCIGGGMGVALAVE 396 >4C2K-A nrPDB Length = 417 Score = 448 bits (1153), Expect = e-126, Method: Composition-based stats. Identities = 156/415 (37%), Positives = 214/415 (51%), Gaps = 25/415 (6%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVN 77 G +P+ + A V VV +RT G G KD T +L A L Sbjct: 13 GLVPRGSHM------ALLRGVFVVAAKRTPFGAYG-GLLKDFTATDLSEFAAKAALSAGK 65 Query: 78 LRPEQLGDICVGNVLQPGAGAI-MARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGG 136 + PE + + +GNVLQ + AI +AR IP+ P T+NR C SG Q++ + Sbjct: 66 VSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQE 125 Query: 137 IRNGSYDIGMACGVESMSLADR-----------GNPGNITSRLMEKEKARDCLIPMGITS 185 I ++ + G ESMS A G+ + L + +PM +T+ Sbjct: 126 ICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTA 185 Query: 186 ENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQD 245 EN+A + ISRE+ D +AL SQQ+ A G F E+ P+ K K T+ D Sbjct: 186 ENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEV-----KTKKGKQTMQVD 240 Query: 246 EGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLR 305 E RP TT+E L KL P FKKDG+ TAGN+S V+DGA A+++A ++ L + Sbjct: 241 EHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIV 300 Query: 306 SYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEK 365 Y V G P IMGIGP AI AL+KAGL++ D+D+ E+NEAFA Q L L K Sbjct: 301 GYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISK 360 Query: 366 VNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 N GGA+ALGHPLG +G+R L++EL+RRG + Y V S CIG G G A + + Sbjct: 361 TNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGK-YAVGSACIGGGQGIAVIIQ 414 >1WL4-A nrPDB Length = 397 Score = 446 bits (1147), Expect = e-125, Method: Composition-based stats. Identities = 163/395 (41%), Positives = 223/395 (56%), Gaps = 19/395 (4%) Query: 38 VVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAG 97 VV+V RT I + G +L S V+ VLK + PE + ++ G+VL G G Sbjct: 8 VVIVSAART-IIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCG 66 Query: 98 AIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLAD 157 R A + IP +VP + C SGL+AV I G I +A G+E+MS A Sbjct: 67 QNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAP 126 Query: 158 R----------GNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQ 207 G S L + MGIT+ENVA+++ +SRE QD A+ SQ Sbjct: 127 HLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQ 186 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 267 + AQ G F EIVPV + K I V DE R + +E ++KLKP F D Sbjct: 187 NRTENAQKAGHFDKEIVPVLVSTR-----KGLIEVKTDEFPRHGSNIEAMSKLKPYFLTD 241 Query: 268 --GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 325 G+ T N+S ++DGAAA++L ++S+A++ GL L + S++ VGV P IMGIGP AI Sbjct: 242 GTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAI 301 Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 A+ KAG ++ DVDIFEINEAFA+ +A V++L L PEKVN GGA+ALGHPLG +G R Sbjct: 302 KQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCR 361 Query: 386 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 ++TLL+ L+R G R+ GV ++CIG GMG A + Sbjct: 362 ILVTLLHTLERMG-RSRGVAALCIGGGMGIAMCVQ 395 >1ULQ-A nrPDB Length = 401 Score = 444 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 171/405 (42%), Positives = 232/405 (57%), Gaps = 26/405 (6%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 + +V RT I + G G PD+LL+ ++ ++ + E++ D+ G Q Sbjct: 1 MPEAWIVEAVRTPIGKHG-GALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQA 59 Query: 95 GAG-AIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G +AR+A L+ P V TVNR C SGL+AVA A I G + + GVESM Sbjct: 60 GEDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESM 119 Query: 154 SLADRGNPG---------------NITSRLME-KEKARDCLIPMGITSENVAERFGISRE 197 S A P + R + K +A MG T+EN+AE +GI RE Sbjct: 120 SRAPYAVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIRRE 179 Query: 198 KQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGL 257 +QD FAL S QKA RA +G FQ E+VPV K K I V QDEG R T++E L Sbjct: 180 EQDRFALLSHQKAVRAWEEGRFQDEVVPVPV-----KRGKEEILVEQDEGPRRDTSLEKL 234 Query: 258 AKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIM 317 A L+P F++ G+ TAGNSS ++DGAAA+LL A+ GL L +R+ AV GVPP IM Sbjct: 235 AALRPVFREGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIM 294 Query: 318 GIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPE--KVNPLGGAVAL 375 GIGP A AL++AGL+ SD+ + E+NEAFA+QA + + L E ++NP GGA+AL Sbjct: 295 GIGPVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIAL 354 Query: 376 GHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 GHPLG +GAR + TL++E++RR K +G+ +MCIG G G A V E Sbjct: 355 GHPLGASGARILTTLVHEMRRR-KVQFGLATMCIGVGQGIAVVVE 398 >6BN2-A nrPDB Length = 401 Score = 443 bits (1140), Expect = e-125, Method: Composition-based stats. Identities = 137/406 (33%), Positives = 216/406 (53%), Gaps = 20/406 (4%) Query: 27 LSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDI 86 ++ +V +V RT + + G +L + + L +NL P ++ D+ Sbjct: 1 MAHHHHHHMKEVFIVSAVRTPMG-SFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQDV 59 Query: 87 CVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGM 146 +GNVLQ G G A+ A + +P T P + VN+ C+SG++AV A ++ G + + Sbjct: 60 YMGNVLQAGEGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIV 119 Query: 147 ACGVESMSLADRGNPGNITSRLMEKEKARDCLI-----------PMGITSENVAERFGIS 195 A G+E+MS G + K +D L+ MG +E A+ + I+ Sbjct: 120 AGGMENMSQVPHYIDG-RNGVKLGDIKLQDGLLKDGLTDVYSKQHMGNCAELCAKEYNIT 178 Query: 196 REKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTME 255 RE+QD FA+ S +++A+A S+G F+ E+VPV+ I +DE + + + Sbjct: 179 REEQDAFAIQSYERSAKAWSEGKFKEEVVPVSIPQRKG----EPIIFAEDEEYK-NVKFD 233 Query: 256 GLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPP 314 + L F+K+ G+ TA N+S ++DGA+A++L + K E LGL L + SYA P Sbjct: 234 RIPTLPTVFQKENGTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAP 293 Query: 315 DIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVA 374 + PA A+P+AL KA LT++D+D FE NEAF+ + L L KVN GGAVA Sbjct: 294 EWFTTAPAKALPIALAKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVA 353 Query: 375 LGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 LGHPLG +G+R ++TL+N LK+ + YG ++C G G +A V E Sbjct: 354 LGHPLGSSGSRIIVTLINVLKQNNAK-YGAAAICNGGGGASAIVIE 398 >2IBU-A nrPDB Length = 395 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 127/402 (31%), Positives = 208/402 (51%), Gaps = 19/402 (4%) Query: 29 GAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICV 88 A + + +VV+V RT I + G +L S + ++ + E++ + + Sbjct: 1 MASKPTLKEVVIVSATRTPIG-SFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYM 59 Query: 89 GNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMAC 148 GNVLQ G G R A + +P + P +T+N+ C+SG++A+ + + G D+ +A Sbjct: 60 GNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAG 119 Query: 149 GVESMSLADRGN-------PGNITSRLMEKEKARDCL--IPMGITSENVAERFGISREKQ 199 G+ESMS G L+ K+ D I MG +EN A++ I+R +Q Sbjct: 120 GMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQ 179 Query: 200 DTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAK 259 D +A+ S ++ A G F E++PVT TV + + V +DE + + K Sbjct: 180 DAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKG----QPDVVVKEDEEYKR-VDFSKVPK 234 Query: 260 LKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMG 318 LK F+K+ G+ TA N+S ++DGAAA++L A+ L + L + ++A V P Sbjct: 235 LKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFP 294 Query: 319 IGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHP 378 I P YA + L+ GL D+ ++E+NEAF+ ++ L + P+KVN GGAV+LGHP Sbjct: 295 IAPVYAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHP 354 Query: 379 LGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 +G +GAR V L + LK+ YG+ S+C G G +A + + Sbjct: 355 IGMSGARIVGHLTHALKQ---GEYGLASICNGGGGASAMLIQ 393 >4WYS-A nrPDB Length = 405 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 161/399 (40%), Positives = 230/399 (57%), Gaps = 19/399 (4%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ 93 + + V+V RTAI + G T+ +L + V+ A ++ + + + ++ +GNVLQ Sbjct: 3 AMKNCVIVSAVRTAIG-SFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQ 61 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G G AR A S + ETV TVN+ C SGL++VA A I+ G +A G+E+M Sbjct: 62 AGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENM 121 Query: 154 SLADRGNPG-NITSRLMEKEKARDCLI-----------PMGITSENVAERFGISREKQDT 201 SLA + + + D ++ MGIT+ENVA+ +GI+RE QD Sbjct: 122 SLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDE 181 Query: 202 FALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLK 261 AL SQ+KAA A G F AEIVPV K++ +QDE + ++T E L L+ Sbjct: 182 LALHSQRKAAAAIESGAFTAEIVPVNVVTR-----KKTFVFSQDEFPKANSTAEALGALR 236 Query: 262 PAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGP 321 PAF K G+ TAGN+S ++DGAAA+++ S A GL L ++SYA GVPP +MG+GP Sbjct: 237 PAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGP 296 Query: 322 AYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGC 381 A ALQ AGL ++D+D+ E NEAFA+Q + L EKVN GGA+ALGHP+G Sbjct: 297 VPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGA 356 Query: 382 TGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 +GAR ++TLL+ ++ R K G+ ++CIG G G A V E Sbjct: 357 SGARILVTLLHAMQARDK-TLGLATLCIGGGQGIAMVIE 394 >4NZS-A nrPDB Length = 399 Score = 434 bits (1115), Expect = e-122, Method: Composition-based stats. Identities = 165/398 (41%), Positives = 223/398 (56%), Gaps = 19/398 (4%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 +VVVV G RTAI G G KD P EL + V+ L + + +G + GNV+Q Sbjct: 7 TREVVVVSGVRTAIGTFG-GSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQT 65 Query: 95 G-AGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 + R+A + P TVNR C SGLQA+ S A I G D+ + G ESM Sbjct: 66 EPRDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESM 125 Query: 154 SLADRGNPGNITSRLMEKEKARDCL----------IPMGITSENVAERFGISREKQDTFA 203 S A P M D + I MG+T+ENVA+ + ISR +QD A Sbjct: 126 SRAPYLAPAARWGARMGDAGLVDMMLGALHDPFHRIHMGVTAENVAKEYDISRAQQDEAA 185 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 L S ++A+ A G F+ +IVPV + KG K +T DE +R T++ + KL+P Sbjct: 186 LESHRRASAAIKAGYFKDQIVPVVS-----KGRKGDVTFDTDEHVRHDATIDDMTKLRPV 240 Query: 264 F-KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPA 322 F K++G+ TAGN+S ++D AAA+++ R++AE GL L L SY GV P MGIGP Sbjct: 241 FVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPV 300 Query: 323 YAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCT 382 A +AL++AGL VSD+D+ E NEAFA+QA + L L P KVNP G ++LGHP+G T Sbjct: 301 PATKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGAT 360 Query: 383 GARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 GA + L+EL R R Y +V+MCIG G G AA+FE Sbjct: 361 GALITVKALHELNRVQGR-YALVTMCIGGGQGIAAIFE 397 >5LP7-H nrPDB Length = 393 Score = 431 bits (1109), Expect = e-121, Method: Composition-based stats. Identities = 150/397 (37%), Positives = 211/397 (53%), Gaps = 17/397 (4%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 V+V RT + G G K+ EL VM L+ + + + +G V+Q Sbjct: 1 MRKTVIVSAARTPFGKFG-GVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQA 59 Query: 95 GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS 154 G+G I +R A L+ +P +VP T+N+ C+SGL+AV IR DI +A G+ESMS Sbjct: 60 GSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMS 119 Query: 155 LADRGNPGNITSRLMEKEKARDCLI-----------PMGITSENVAERFGISREKQDTFA 203 P M + RD ++ M + A+ + ISR +QD +A Sbjct: 120 NIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQDEWA 179 Query: 204 LASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPA 263 L S +AA+A +G FQ EIVPV K V +DE IR T+++ LAKL P Sbjct: 180 LRSHARAAKAADEGKFQDEIVPVNWIGRKGKPN----VVDKDEAIRRDTSLDQLAKLAPI 235 Query: 264 FKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY 323 + DGS TAGN+ V+DGA A +L KA ELG L + ++ G+P + P + Sbjct: 236 YASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGF 295 Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 AI L+K GLTV D+D+FE+NEAFAS C + + EKVN GGA+ALGHP+G +G Sbjct: 296 AINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASG 355 Query: 384 ARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 AR ++TL+ ELKRRG GV ++C G G A + + Sbjct: 356 ARILMTLVYELKRRGG-GLGVAAICSGAAQGDAVLVQ 391 >1PXT-A nrPDB Length = 390 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 203/392 (51%), Positives = 253/392 (64%), Gaps = 19/392 (4%) Query: 36 ADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKD----VNLRPEQLGDICVGNV 91 DVV+V R+AI + +G FKD D LL + + + + ++ GNV Sbjct: 7 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 66 Query: 92 LQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 L GAGA R A S IP + P +NRQCSSGL AV IA I+ G DIG+A GVE Sbjct: 67 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 126 Query: 152 SMSLADRGNP--GNITSRLMEKEK-ARDCLIPMGITSENVAERFGISREKQDTFALASQQ 208 SM+ + G I+S ++K + A+ CLIPMGIT+ENVA F ISR+ QD FA S Q Sbjct: 127 SMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQ 186 Query: 209 KAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD- 267 KA +A+++G F+ EI+P+ DEG RP+ T E L+ ++PAF KD Sbjct: 187 KAYKAKNEGLFEDEILPIKLP--------DGSICQSDEGPRPNVTAESLSSIRPAFIKDR 238 Query: 268 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 327 G+TTAGN+SQVSDG A +LLARRS A +L LP+LG + VGVPP+IMG+GPAYAIP Sbjct: 239 GTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPK 298 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 387 L+ GL V D+DIFEINEAFA+QA YC+ KL + KVNP GGA+ALGHPLGCTGARQV Sbjct: 299 VLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQV 358 Query: 388 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVF 419 T+L ELK K GVVSMCIGTGMGAAA+F Sbjct: 359 ATILRELK---KDQIGVVSMCIGTGMGAAAIF 387 >6ARG-A nrPDB Length = 399 Score = 422 bits (1085), Expect = e-118, Method: Composition-based stats. Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 19/401 (4%) Query: 33 ASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDV-NLRPEQLGDICVGNV 91 +S V +V RT + + G T +L + + A L V L+P + ++ GNV Sbjct: 3 SSLPAVYIVSSARTPVG-SFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNV 61 Query: 92 LQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 + G AR + + E+ +TVN+ C+SGL+A+ A I G+ D+ +A G E Sbjct: 62 ISANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTE 121 Query: 152 SMSLADRGNPGNITSRLMEKEKARDCLIP-----------MGITSENVAERFGISREKQD 200 SMS A P T + D ++ MG+ +E A+ G SRE+QD Sbjct: 122 SMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQD 181 Query: 201 TFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKL 260 +A+ + +KA AQ G F EI P+ K +TVTQDE + + E L + Sbjct: 182 EYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGK---PDVTVTQDEEPK-NLNPEKLRAI 237 Query: 261 KPAFKK-DGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGI 319 KPAF G+ TA NSS ++DGAAA++L +K +EL L + + + P Sbjct: 238 KPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTT 297 Query: 320 GPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPL 379 PA AIP AL+ AG+ +D FEINEAF+ A ++ L +P EKVN GGAVA+GHP+ Sbjct: 298 APALAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPI 357 Query: 380 GCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 G +GAR + TLL LK + + G +C G G +A V E Sbjct: 358 GASGARILTTLLGVLKAKKGK-LGCAGICNGGGGASALVVE 397 >1WDK-C nrPDB Length = 390 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 160/394 (40%), Positives = 234/394 (59%), Gaps = 19/394 (4%) Query: 36 ADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKD-VNLRPEQLGDICVGNVLQP 94 DVV+V RT + R+ G ++T +++ + +++ VL+ + P ++ D+ G V Q Sbjct: 5 RDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQT 64 Query: 95 -GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G +AR+A ++ IP T TV+R C S + A+ + A I G+ D+ + GVE M Sbjct: 65 LEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHM 124 Query: 154 ---SLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKA 210 S+ +P S K MG+T+E + + GISRE+QD FA+ S Q A Sbjct: 125 GHVSMMHGVDPNPHMSLYAAKASGM-----MGLTAEMLGKMHGISREQQDAFAVRSHQLA 179 Query: 211 ARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK-KDGS 269 +A +G F+ EI+P+ +D+ G + DE IRP TT+E LA LKPAF K G+ Sbjct: 180 HKATVEGKFKDEIIPMQ--GYDENGFLK--IFDYDETIRPDTTLESLAALKPAFNPKGGT 235 Query: 270 TTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVAL 329 TAG SSQ++DGA+ +++ +A++LGL L V+RS AV GV P IMG GP A AL Sbjct: 236 VTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKAL 295 Query: 330 QKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPP---EKVNPLGGAVALGHPLGCTGARQ 386 ++AGL ++D+D E+NEAFA+QA ++ L++ EKVN GGA+ALGHP GC+GAR Sbjct: 296 KRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARI 355 Query: 387 VITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 TLLN +K+ G +G+ +MCIG G G A VFE Sbjct: 356 SGTLLNVMKQNGG-TFGLSTMCIGLGQGIATVFE 388 >3GOA-A nrPDB Length = 387 Score = 420 bits (1080), Expect = e-118, Method: Composition-based stats. Identities = 165/392 (42%), Positives = 225/392 (57%), Gaps = 13/392 (3%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKD-VNLRPEQLGDICVGNVLQ 93 VV+V RT + R+ G F++ ++L + +M ++L +L L DI G V Q Sbjct: 1 MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQ 60 Query: 94 P-GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 G +AR A L++IP +VP TVNR C S +QA+ A I G + + GVE Sbjct: 61 TLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEH 120 Query: 153 MSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAAR 212 M + + L + MG+T+E ++ GISRE QD FA S +A Sbjct: 121 MGHVPMSHGVDFHPGLSRNVAKAAGM--MGLTAEMLSRLHGISREMQDQFAARSHARAWA 178 Query: 213 AQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKK-DGSTT 271 A G F+ EI+P T HD G + DE IRP TT+E L+ L+PAF G+ T Sbjct: 179 ATQSGAFKTEIIP--TGGHDADGVLKQ--FNYDEVIRPETTVEALSTLRPAFDPVSGTVT 234 Query: 272 AGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQK 331 AG SS +SDGAAA+L+ S+A ELGL +RS AVVG P IMG GP A +AL+K Sbjct: 235 AGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKLALKK 294 Query: 332 AGLTVSDVDIFEINEAFASQAAYCVEKLRLP---PEKVNPLGGAVALGHPLGCTGARQVI 388 AGL+ SD+D+FE+NEAFA+Q C++ L L EK+N GGA+ALGHPLGC+GAR Sbjct: 295 AGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARIST 354 Query: 389 TLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 TL+N ++R+ + +G+ +MCIG G G A VFE Sbjct: 355 TLINLMERKDAQ-FGLATMCIGLGQGIATVFE 385 >3SVK-A nrPDB Length = 407 Score = 418 bits (1074), Expect = e-117, Method: Composition-based stats. Identities = 148/413 (35%), Positives = 212/413 (51%), Gaps = 32/413 (7%) Query: 31 PQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKD-VNLRPEQLGDICVG 89 P + + + + RT + G + P L+ ++ + + +L + D+ +G Sbjct: 2 PGSMSEEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPDLDETLISDMILG 61 Query: 90 NVLQPG-AGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMAC 148 V G G +AR A + +PET +NR C+SGL+AV + A +R+G D+ +A Sbjct: 62 VVSPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAG 121 Query: 149 GVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQ 208 GVESMS G+ G + E R +P GI ++ +A G SRE D +AL SQQ Sbjct: 122 GVESMSRVPMGSDGGAWATDPE-TNYRIGFVPQGIGADLIATLEGFSREDVDAYALRSQQ 180 Query: 209 KAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF---- 264 KAA A S G F +VPV + + + DE +RP TTMEGLAKLK AF Sbjct: 181 KAAAAWSGGYFAKSVVPV-------RDQNGLVILDHDEHMRPDTTMEGLAKLKTAFDGVG 233 Query: 265 -----------------KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSY 307 K + T GNSS + DGAA +L+ + GL + + Sbjct: 234 EMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPRARIVAT 293 Query: 308 AVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVN 367 A G P IM GP A L +AGLT+ D+D+FE+NEAFAS + L +P EK+N Sbjct: 294 ATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIPDEKLN 353 Query: 368 PLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 GGA+A+GHPLG TGA T+++EL+RR R ++++CIG GMG A + E Sbjct: 354 VNGGAIAMGHPLGATGAMITGTMVDELERRNAR-RALITLCIGGGMGVATIIE 405 >5CBQ-A nrPDB Length = 413 Score = 417 bits (1073), Expect = e-117, Method: Composition-based stats. Identities = 156/408 (38%), Positives = 216/408 (52%), Gaps = 28/408 (6%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQ 93 S D V+ RT I R G G F+ T +L + +L+ + +Q+ D+ +G+ Sbjct: 8 SMRDAVICEPVRTPIGRYG-GMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCYP 66 Query: 94 PGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 + R+ + +P TVP V+R+C SGLQAV +R+G +D+ +A G ESM Sbjct: 67 NSEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESM 126 Query: 154 SLA-----DRGNPGNITSRLMEKEKARDCLIP----------MGITSENVAERFGISREK 198 S D G T + AR M T+EN+ + ISR + Sbjct: 127 SNVAFYSTDMRWGGARTGVQIHDGLARGRTTAGGKFHPVPGGMLETAENLRREYHISRTE 186 Query: 199 QDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLA 258 QD A+ S Q+A AQS+G EI+PV D + T++ DE R TT+E LA Sbjct: 187 QDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEE-----TISVDEHPRADTTVEALA 241 Query: 259 KLKPAFKK---DGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPD 315 KLKP K + + TAGNSS +D A+ ++ KA ELGL L L S+ GV PD Sbjct: 242 KLKPVLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPD 301 Query: 316 IMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRL---PPEKVNPLGGA 372 +MGIGP A VAL KAGLT++D+D+ E+NEAFA+QA + + + E+ N G Sbjct: 302 LMGIGPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSG 361 Query: 373 VALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 ++LGHP+G TG R + TL EL RR R YG+ +MCIG G G AAVFE Sbjct: 362 ISLGHPVGATGGRMLATLARELHRREAR-YGLETMCIGGGQGLAAVFE 408 >5XYJ-B nrPDB Length = 408 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 134/404 (33%), Positives = 204/404 (50%), Gaps = 21/404 (5%) Query: 32 QASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDV-NLRPE-QLGDICVG 89 + + +V +V RT I + +G T EL + + L V L +I G Sbjct: 9 GSMSQNVYIVSTARTPIG-SFQGSLSSKTAVELGAVALKGALAKVPELDASKDFDEIIFG 67 Query: 90 NVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACG 149 NVL G AR + + + STVN+ +S ++A+ A I+ G+ D+ +A G Sbjct: 68 NVLSANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGG 127 Query: 150 VESMSLADRGNPGNITSRLMEKEKARDCL-----------IPMGITSENVAERFGISREK 198 ESM+ A P + D + + MG+ +E A + I+RE+ Sbjct: 128 CESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQ 187 Query: 199 QDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLA 258 QD FA+ S QK+ ++Q +G F EIVPVT K VT+DE +E L Sbjct: 188 QDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGK---PDTQVTKDEEP-ARLHVEKLR 243 Query: 259 KLKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIM 317 + F+K+ G+ TA N+S ++DGAAA++L +E L L +++ + P Sbjct: 244 SARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADF 303 Query: 318 GIGPAYAIPVALQKAGLT-VSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALG 376 P+ A+P AL+ AG+ ++ VD FE NEAF+ + L+L P KVN GGAVALG Sbjct: 304 TWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALG 363 Query: 377 HPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 HPLGC+GAR V+TLL+ L++ G + GV ++C G G ++ V E Sbjct: 364 HPLGCSGARVVVTLLSILQQEGGK-IGVAAICNGGGGASSIVIE 406 >6BJA-A nrPDB Length = 397 Score = 406 bits (1043), Expect = e-113, Method: Composition-based stats. Identities = 136/396 (34%), Positives = 204/396 (51%), Gaps = 20/396 (5%) Query: 36 ADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPG 95 DV ++ RT I + R + +L V +K L + + VGNVL G Sbjct: 9 KDVYILSAVRTPI-ASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAG 67 Query: 96 AGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155 G +AR S+IP++ T+N+ CSS ++A+ A I+ G I +A G ESMS Sbjct: 68 LGQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSN 127 Query: 156 ADRGNP-GNIT--SRLMEKEKARDCLI------PMGITSENVAERFGISREKQDTFALAS 206 A P G I + RD L+ PMG+ +E + + +RE+ D +A+ S Sbjct: 128 APFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQPMGLCAEKTVKDYAFTREQLDAYAIES 187 Query: 207 QQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKK 266 +KA A +G F E+VPV+ + +T+DE + E + L PAF K Sbjct: 188 YRKAEHAWKEGAFNKEVVPVSVPQKRGS----KVVLTEDEEYKR-LIPEKVPALHPAFLK 242 Query: 267 DG--STTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYA 324 DG + TA N+S ++DGAAA +LA +E L + + SYA GV P + PA A Sbjct: 243 DGSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALA 302 Query: 325 IPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 + L ++GL + ++EINEAF+ +++LRL P++VN GGAVALGHPLG +GA Sbjct: 303 VKQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGA 362 Query: 385 RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 R V+TL++ LK GV ++C G G +A + + Sbjct: 363 RIVVTLVHALK---SDELGVAAICNGGGEASAILIK 395 >4B3J-C nrPDB Length = 403 Score = 403 bits (1036), Expect = e-113, Method: Composition-based stats. Identities = 146/411 (35%), Positives = 210/411 (51%), Gaps = 34/411 (8%) Query: 34 SAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKD-VNLRPEQLGDICVGNVL 92 + + + RT + G + P L+ ++ + K +L + D+ +G V Sbjct: 1 MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLISDVILGCVS 60 Query: 93 QPG-AGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 G G +AR A S +P T +NR C+SGL+AV + A +R+G D+ +A GVE Sbjct: 61 PVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVE 120 Query: 152 SMSLADRGNPGNITSRLMEKEKARDCLI-PMGITSENVAERFGISREKQDTFALASQQKA 210 SMS G+ G ++ D + P I ++ +A G SRE D +AL SQQKA Sbjct: 121 SMSRVPMGSDGGAMG--LDPATNYDVMFVPQSIGADLIATIEGFSREDVDAYALRSQQKA 178 Query: 211 ARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF------ 264 A A S G F +VPV + + + DE +RP TT EGLAKLKPAF Sbjct: 179 AEAWSGGYFAKSVVPV-------RDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAAL 231 Query: 265 ---------------KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAV 309 K + T GNSS + DGAA +++ + + GL + + A Sbjct: 232 GGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVATAT 291 Query: 310 VGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPL 369 G P IM GP A L +AGLTV D+D+FE+NEAFAS + L +P EK+N Sbjct: 292 SGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVN 351 Query: 370 GGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 GGA+A+GHPLG TGA + T+++EL+RR R ++++CIG GMG A + E Sbjct: 352 GGAIAMGHPLGATGAMILGTMVDELERRNAR-RALITLCIGGGMGVATIIE 401 >6BJB-A nrPDB Length = 393 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 132/393 (33%), Positives = 205/393 (52%), Gaps = 19/393 (4%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 DVV V RT I + R F + L + LK+ N++P + + +G V+ A Sbjct: 9 DVVFVGAARTPIG-SFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNA 67 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 G AR + + ++ VN+ +SG++A+A A ++ ++ +A G+ESMS Sbjct: 68 GQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCV 127 Query: 157 DRGNP-------GNITSRLMEKEKARDCL--IPMGITSENVAERFGISREKQDTFALASQ 207 P G + ++ D I MG ++ VA++F I+RE+QD +A+ S Sbjct: 128 PFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAILSY 187 Query: 208 QKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD 267 +++A A +G F EI+P+ T K++ITV +DE + E + KLKPAF + Sbjct: 188 KRSAAAWKEGIFAKEIIPLEVTQ-----GKKTITVEEDEEYK-KVNFEKIPKLKPAFTSE 241 Query: 268 GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPV 327 GS TA N+S ++DGAA +++ A++ GL L + +Y P GI PA IP Sbjct: 242 GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPK 301 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 387 L+ AGL + D+D++EINEAFA Y ++ L L KVN GGAV+LGHP+G +GAR V Sbjct: 302 VLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIV 361 Query: 388 ITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 L++ LK G ++C G G + E Sbjct: 362 GHLVHTLK---PGQKGCAAICNGGGGAGGMIIE 391 >5ZQZ-B nrPDB Length = 474 Score = 376 bits (966), Expect = e-105, Method: Composition-based stats. Identities = 154/453 (33%), Positives = 222/453 (49%), Gaps = 64/453 (14%) Query: 22 QAAPCLSGAPQ-----ASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDV 76 +AAP + + + +VVVV G RT +G +KD P +L A +T +L Sbjct: 33 RAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSG-TSYKDLMPHDLARAALTGLLHRT 91 Query: 77 NLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGG 136 ++ E + I G V+Q + +AR A + + P TV C S QA+ + G Sbjct: 92 SVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGL 151 Query: 137 IRNGSYDIGMACGVESMSLAD-------------RGNPGNITSRLMEKEKAR-DCLIP-- 180 I +G D+ +A GVE MS ++ RL K R + L P Sbjct: 152 IASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPEL 211 Query: 181 -----------MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTT 229 MG +++ +A F +SR +QD +AL S A +AQ +G +VP Sbjct: 212 PAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP 270 Query: 230 VHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF-KKDGSTTAGNSSQVSDGAAAILLA 288 D TVT+D GIRPS ++E +AKLKPAF K G+ TA NSS ++DGA+A+L+ Sbjct: 271 GKD--------TVTKDNGIRPS-SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIM 321 Query: 289 RRSKAEELGLPILGVLRSYAVVGVPP-DIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA 347 KA +G LR + V P D + +GP YA P L+KAGLT++D+D FE +EA Sbjct: 322 AEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEA 381 Query: 348 FASQAAYCVE----------------KLRLPP-EKVNPLGGAVALGHPLGCTGARQVITL 390 F+ Q + K+ LPP EK N GG+++LGHP G TG R V+ Sbjct: 382 FSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAA 441 Query: 391 LNELKRRGKRAYGVVSMCIGTGMGAAAVFE-YP 422 N L++ G + YG+V+ C G G A + E YP Sbjct: 442 ANRLRKEGGQ-YGLVAACAAGGQGHAMIVEAYP 473 >4UBW-A nrPDB Length = 399 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 143/390 (36%), Positives = 211/390 (54%), Gaps = 13/390 (3%) Query: 39 VVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLR----PEQLGDICVGNVLQP 94 V+V R+ I + G ELL AV AV+ ++ + + G V Q Sbjct: 13 VIVEATRSPIGKR-NGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQF 71 Query: 95 GAGAI-MARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 G + ++R+A + +PE V +TV+ QC SG QA IAG I G+ D+G+ACG+E+M Sbjct: 72 GEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAM 131 Query: 154 SLADRGNPGNITSRLMEKEKARDCLIPMGI-TSENVAERFGISREKQDTFALASQQKAAR 212 S G R + + ++ D +P +E +A+R GI+RE D F L SQ++A R Sbjct: 132 SRVGLGANAG-PDRSLIRAQSWDIDLPNQFEAAERIAKRRGITREDVDVFGLESQRRAQR 190 Query: 213 AQSKGCFQAEIVPVTTTVHDDKG--TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGST 270 A ++G F EI P+ V D++ T V +D+G+R TTM GL +LKP + G Sbjct: 191 AWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLR-ETTMAGLGELKPVLE-GGIH 248 Query: 271 TAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQ 330 TAG SSQ+SDGAAA+L + A GL + + A+VG P GP + L+ Sbjct: 249 TAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDGPVQSTAKVLE 308 Query: 331 KAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITL 390 KAG+ + D+DI EINEAFAS ++VN GGA+ALGHP+GCTG+R + T Sbjct: 309 KAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSRLITTA 368 Query: 391 LNELKRRGKRAYGVVSMCIGTGMGAAAVFE 420 L+EL+R ++ +++MC G + + E Sbjct: 369 LHELERTD-QSLALITMCAGGALSTGTIIE 397 >6ESQ-A nrPDB Length = 392 Score = 257 bits (658), Expect = 5e-69, Method: Composition-based stats. Identities = 90/414 (21%), Positives = 157/414 (37%), Gaps = 78/414 (18%) Query: 44 RRTAICRAGRGGFKDTTPDELLSAVMTA---VLKDVNLRPEQLGDICVGNVLQPGAGAIM 100 R AI G+ F + D ++ A +KD N+ + + +GN + G Sbjct: 2 RDVAIIGYGQTKFGELWEDSFRDLIVEAGVKAIKDANVDGGDIDAMYIGN-MSGGLFVGQ 60 Query: 101 ARIAQFLSDIP--ETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR 158 IA ++D VP + V C+SG A+ S + +G +D+ +A GVE M+ + Sbjct: 61 EHIASLIADHAGLNPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAGGVEKMTDVED 120 Query: 159 GNPGNITSRLMEKEKARDCLIP--MGITSENVAERFGISREKQDTFALASQQKAARAQSK 216 ++ E E P + + ++G++ E+ +++ + + A + Sbjct: 121 ATAAIASASDQEWEAFFGATFPSLYAMMARRYMYQYGLTIEELSMWSVIAHENATK---- 176 Query: 217 GCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSS 276 +K + T ++ + S + L T + S Sbjct: 177 ----------------NKYAQFGFKTTLEQVMNASPVADPL-------------TLMHCS 207 Query: 277 QVSDGAAAILLARRSKAEELG-----LPILGVLRSYAVVGVP--PDIMGIGPA-YAIPVA 328 VSDGA+A+++ KAEE + I ++ + + D+ + A A A Sbjct: 208 PVSDGASALIVCDADKAEEFAPKDEIIYIKASTQASDTIALHDREDMTTLNAAKVASEKA 267 Query: 329 LQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEK--------------------VNP 368 + A + +D+ E+++ FA VE L + VNP Sbjct: 268 YKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFCKKGDAGKVIDEGKIRIDYDDFVTVNP 327 Query: 369 LGGAVALGHPLGCTGARQVITLLNELKRRG---------KRAYGVVSMCIGTGM 413 GG A GH LG TG RQV L +LK+ K YG+ + GTG Sbjct: 328 SGGLKAAGHALGATGIRQVGELYWQLKQDKECKDRQATIKNGYGIAANVGGTGG 381 >4BI9-A nrPDB Length = 454 Score = 255 bits (651), Expect = 3e-68, Method: Composition-based stats. Identities = 101/439 (23%), Positives = 156/439 (35%), Gaps = 87/439 (19%) Query: 17 SGWMPQAAPCLS-GAPQASAADVVVVHGRRTAICRAGRGGFKDT-----------TPDEL 64 SG +P+ + L + SA V VV G T G F D T +EL Sbjct: 8 SGLVPRGSHMLRRTSSTFSAKRVFVVGGHITTFVGKGSPLFIDKKHPDFGKKENKTLEEL 67 Query: 65 LSAVMTAVLKDVNL---RPEQLGDICVGNVL------QPGAG-AIMARIAQFLSDIPETV 114 L+ + L++ L R + + VGN L Q G A + ++ S Sbjct: 68 LAESINGALQNTGLHDGRAALVDKLVVGNFLGELFSSQGHLGPAAVGSLSGSNSSAFLNK 127 Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKA 174 P V C+SG AV S + G+ I +A GVE + G+ +R Sbjct: 128 PAVRVEGACASGGLAVQSAWEALLAGTSQIALAVGVEVQTTVSARVGGDYLAR------- 180 Query: 175 RDCLIPMGITSENVAERFGISREKQD-TFALASQQKAARAQSKGCFQAEIVPVTTTVHDD 233 A + R+ D TF ++ Q G F E Sbjct: 181 --------------AAHYKRQRQLDDFTFPCLFARRMKAIQEAGHFTMEDAAYVAAKAYA 226 Query: 234 KGTKRSI------TVTQD---EGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAA 284 G + + VT D + + G KP + + SQVSDG AA Sbjct: 227 SGNRNPLAHMHARKVTLDFCTQASDKNPNFLGNEIYKPFLRTT------DCSQVSDGGAA 280 Query: 285 ILLARRSKAEELGLPI----LGVLRSYAVVG-----VPPDIMGIGPAY-AIPVALQKAGL 334 ++LA ++LGL L ++S A PD+ + + A AL AG+ Sbjct: 281 VILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMVAARTALSMAGV 340 Query: 335 TVSDVDIFEINEAFASQAAYCVEKLRLPPEK------------------VNPLGGAVALG 376 + + E+++ F E L + VN GG ++ G Sbjct: 341 KPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIRSGATALDGRIPVNTGGGLLSFG 400 Query: 377 HPLGCTGARQVITLLNELK 395 HP+G TG +QV+ + ++K Sbjct: 401 HPVGATGVKQVLEVYRQMK 419 >6HRV-A nrPDB Length = 421 Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats. Identities = 84/394 (21%), Positives = 144/394 (36%), Gaps = 61/394 (15%) Query: 37 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96 V V+ T + + G +D ++ L D ++ + CVG V Sbjct: 15 RVFVIGVGMT---KFEKPGARDIDYPDMAKEAGQRALADAGIKYSAIQQACVGYVY---G 68 Query: 97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 + + A + S +P+ VN CS+G A+ I+ G D +A G E M Sbjct: 69 DSTCGQRAIYHSLGLSGIPIINVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEKMER- 127 Query: 157 DRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISR--EKQDTFALASQQKAARAQ 214 G+++S+ M++ PM E + R+G++ F A ++ + Sbjct: 128 -----GSLSSKYMDRTN------PMDKHMEVMINRYGLAAVPAAPQMFGNAGREHMEKYG 176 Query: 215 SKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGN 274 + + E + T + QDE ++E + + F+ T Sbjct: 177 T----KPEHFAKVAWKNHKHSTNNPYSQFQDEY-----SLEQVIDSRKVFE---FLTLLQ 224 Query: 275 SSQVSDGAAAILLARRSKAEELGLPILG-------VLRSYAVVGVPPDIMGIGPAYAIPV 327 SDGA A +LA S GL ++ + M + + Sbjct: 225 CCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLSTTFEENSCMKMVGYDMTRL 284 Query: 328 ALQK----AGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEK------------------ 365 A ++ AG+ SDVD+ E+++ F++ E L L PE Sbjct: 285 AAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGELIDRGDNTYGGKWV 344 Query: 366 VNPLGGAVALGHPLGCTGARQVITLLNELKRRGK 399 +NP GG ++ GHPLG TG Q L +L+ Sbjct: 345 INPSGGLISKGHPLGATGLAQCAELCWQLRAEAG 378 >5LNQ-A nrPDB Length = 457 Score = 247 bits (630), Expect = 8e-66, Method: Composition-based stats. Identities = 94/436 (21%), Positives = 159/436 (36%), Gaps = 78/436 (17%) Query: 17 SGWMPQAAPCLSGAPQ--ASAADVVVVHGRRTAICRAGRGGF-----------KDTTPDE 63 SG +P+ + + +A+ V +V G T G F K+ T +E Sbjct: 8 SGLVPRGSHMFRSSLTHLQAASRVFIVGGHITPFVGKGSPLFIDKKHPDFGKKKNMTLEE 67 Query: 64 LLSAVMTAVLKDVNLRPEQ--LGDICVGNVL------QPGAG-AIMARIAQFLSDIPET- 113 +L+ + ++ L + + + VGN L Q G A + + + Sbjct: 68 ILATTVQGTMEHSGLSGREGIVDQVVVGNFLGELFSSQGHLGPAAIGSLTYGQAGSKNPL 127 Query: 114 --VPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEK 171 P V +SG AV S +++GS DI +A GVE + A G+ +R + Sbjct: 128 MYKPAMRVEGAAASGGLAVISAMNALKSGSADITLAVGVEVQTTASARVGGDYLARAADY 187 Query: 172 EKAR---DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT 228 ++ R D P A+R E + F + + AR +K P+ Sbjct: 188 QRQRQLDDFTFPCLF-----AKRMKYIAE-HNHFTM---EDTARVAAKAYANGNKNPLAH 238 Query: 229 TVHDDKGTKRSITVTQDEGIRPSTT-MEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILL 287 R +T Q G PS G K + + SQVSDG A ++L Sbjct: 239 M------HTRKLTFEQCNGEDPSNVKFLGNETYKEYLRMT------DCSQVSDGGAGVVL 286 Query: 288 ARRSKAEELGLPI--------LGVLRSYAVVGVPPD--IMGIGPAYAIPVALQKAGLTVS 337 A ++GL + + + + PD A AL A + S Sbjct: 287 ANEEGLRKMGLSPNDSRLVEIKSIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPS 346 Query: 338 DVDIFEINEAFASQAAYCVEKLRLPPEK------------------VNPLGGAVALGHPL 379 D+++ E+++ F E L + VN GG ++ GHP+ Sbjct: 347 DLNVAEVHDCFTIAEMLMYEALGIAEYGHAKDLIRNGDTTLEGRIPVNTGGGLLSFGHPV 406 Query: 380 GCTGARQVITLLNELK 395 G TG +Q++ + ++K Sbjct: 407 GATGIKQIMEVYRQMK 422 >4YZO-A nrPDB Length = 373 Score = 114 bits (285), Expect = 8e-26, Method: Composition-based stats. Identities = 73/416 (17%), Positives = 129/416 (31%), Gaps = 83/416 (19%) Query: 38 VVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAG 97 V +V T + F +L+ V +LK + + V N Sbjct: 2 VAIVDVGITKFGKRKENIF------DLVKEVTEKLLK------YDIDYVIVSNSYSGEFN 49 Query: 98 AIMARIAQFLSDI-PETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 + + + + VP V+ SG A+ + + + + GVE MS Sbjct: 50 QTSGLSSLITTYLNLDYVPSLRVDNTSGSGGSAILVAKSLLESKEANTVLVVGVEKMSEK 109 Query: 157 DRGNPGNITSRLMEKEKARDCLIP--MGITSENVAERFGISREKQDTFALASQQKAARAQ 214 I S L+ E+ R +P I++ +F RE A+ + Sbjct: 110 KTREVTKIISSLLPFEE-RIASLPSLASISAIEYMRKFNAPRESIAQVAVKNH------- 161 Query: 215 SKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGN 274 + + P VT +E + E L + Sbjct: 162 ----YNGSLNPFAHIQKR---------VTLEEVLNSPVISEPLRLYE------------- 195 Query: 275 SSQVSDGAAAILLARRSKAEELGLPILGVLRSYA----VVGV-PPDIMGIGPAY--AIPV 327 + +SDGAAA+++ R A + ++ V + PA A Sbjct: 196 YTPISDGAAAVVMVRNEDALSYTSKPV-YIKGIGSSNYTAYVSEKEDFVTLPAVVEASRK 254 Query: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRL-----------------PPE-KVNPL 369 A +KA V +D E+++ E + L E +NP Sbjct: 255 AFKKA--KVERIDFAELHDMATILEIIQSEDIGLFKKGEGWKAVMEGLTSLDGEIPINPS 312 Query: 370 GGAVALGHPLGCTGARQVITLLNELKRRGKR------AYGVVSMCIGTGMGAAAVF 419 GG + GHP+G +G Q + ++++ G+ G G A + Sbjct: 313 GGLNSKGHPIGASGVAQAVEAFSQIRNEAGNRQVKNARVGLSLSMAGYGNSATVII 368 >5M3K-C nrPDB Length = 398 Score = 87.3 bits (215), Expect = 1e-17, Method: Composition-based stats. Identities = 71/434 (16%), Positives = 127/434 (29%), Gaps = 91/434 (20%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGN---- 90 A V +V T + G + T E++ LKD + P ++ + G Sbjct: 3 ARRVAIVSAAYTP--KPGSSRVRQTF-KEMIVESAYKALKDAKMHPREIQAVAYGYHGEG 59 Query: 91 -VLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACG 149 G G ++ + P C+S + + +G YDI + G Sbjct: 60 ISEYGGLGPTIS-----DALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDIVLCGG 114 Query: 150 VESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQK 209 E M+ +S E + GIS D FALA+ + Sbjct: 115 FEKMTDHFNYAEYIGSSTECEYDYFL-----------------GISHT--DAFALATAEY 155 Query: 210 AARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGS 269 + G + + + T R + L LK + Sbjct: 156 FQKFGYAGREADVLATFGRQMRIYAQNTPTAT-------RYGQPIPSLEVLKNSEACGSM 208 Query: 270 TTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVP---------------- 313 G +S +L A + + +R A GV Sbjct: 209 LAWGEASG------CAILVAEHLAHKYTDKPV-FVRGCAYTGVSHYFGTRFHNPTLHHPG 261 Query: 314 -PDIMGIG----PAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEK--- 365 P +G+ +A +KAG+T D+D+ ++ + + +E + + + Sbjct: 262 LPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGA-GLIQMESMGICGKGQAG 320 Query: 366 ---------------VNPLGGAVALGHPLGCTGARQVITLLNELK-----RRGKRAYGVV 405 +N GG + GH GC G + L +L+ + GV Sbjct: 321 DFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQLRGESDNQVKGARIGVS 380 Query: 406 SMCIGTGMGAAAVF 419 G + + Sbjct: 381 QNLGGYAAHNSVIV 394 >4U4E-A nrPDB Length = 383 Score = 77.3 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 57/371 (15%), Positives = 115/371 (30%), Gaps = 61/371 (16%) Query: 54 GGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPET 113 G D L + L++ L + + + G + P Sbjct: 20 GKVPDKPAIALHAEAALNALEEAGLTLRDVDGLLTAGISPLELGEYLGIE-------PSY 72 Query: 114 VPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEK 173 + V SS + +A A I G + + ES + G P + + + + Sbjct: 73 TDGTAVGG--SSFVIHLAHAAAAIVTGRCSVALITHGES-GRSRVGMPPRVPAPDSLRGQ 129 Query: 174 ARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDD 233 D P G+ + A +ALA + A G + ++ + Sbjct: 130 FED---PYGLPTPVGA------------YALACSRHMAEY---GTTKEQLAEIAVATRKW 171 Query: 234 KGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKA 293 +R T+E + +P + V+D A ++ +A Sbjct: 172 AMLNPKA------YMRDPITIEDVLNSRPIVWP---FNLLDCCLVTDAGGACVVTSIERA 222 Query: 294 EELGLPILGVL-----RSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAF 348 +L + +L ++++ P + + A + AG+T D+D+ I ++F Sbjct: 223 RDLRQHPVAILGVGESHDHSIISQMPSLTSFAARRSGQAAFKMAGVTHDDIDLAMIYDSF 282 Query: 349 ASQAAYCVEKLRLPPEK------------------VNPLGGAVALGHPLGCTGARQVITL 390 +E L + +N GG ++ HP G G +I Sbjct: 283 TYTVLLSLEDLGFCAKGEGGAFVSGQRTAPGGDFPMNTNGGGLSYTHP-GMYGMFAIIEA 341 Query: 391 LNELKRRGKRA 401 + +L+ Sbjct: 342 VRQLRHDYADQ 352 >5AB6-A nrPDB Length = 425 Score = 61.5 bits (148), Expect = 6e-10, Method: Composition-based stats. Identities = 72/415 (17%), Positives = 123/415 (29%), Gaps = 103/415 (24%) Query: 17 SGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDV 76 SG +P+ + S V +V RT I + K DEL ++ + L D Sbjct: 8 SGLVPRGSHMASQV-------VRIVGVGRTGIGK----LHKSV--DELAASALKCALVDA 54 Query: 77 NLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPET--VPLSTVNRQCSSGLQAVASIA 134 N++ L + L IA P + TV+ + + A+ Sbjct: 55 NMKQCDLQALIAVPSLASPQFMQAHHIATVAGLFPTKGKFIVRTVDTGGAGPITALGMAV 114 Query: 135 GGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGI--TSENVAERF 192 +R + +++ G ++ + + + IP G ++ R+ Sbjct: 115 DLVRTRCAETVAVIAADAVLSMGSGAFAERSNASLRRSGLPEPCIPHGYDRYAQWYMSRY 174 Query: 193 GISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPST 252 G+ RE+ + + A R C +A T DE + Sbjct: 175 GLKREQLAMVPVLMSKMAERHPEAMCQKA--------------------YTLDEVLHSRC 214 Query: 253 TMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEEL------------GLPI 300 P T ++ +DGA A++++ + E G Sbjct: 215 VA-------PV------TNLLECARRADGAVALIVSGEAHYAEHFAQGKQEQRHLGGSKP 261 Query: 301 LGVLRSYAVVGVP-----------PDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFA 349 + + S A P PDI +A A A L V D+ F + + F Sbjct: 262 I--IASVAEASGPLFPPGSSDDIVPDIFSC--RHAARDAFLSANLNVGDIHFFGLYDCFP 317 Query: 350 SQAAYCVEKLRLPPEK--------------------------VNPLGGAVALGHP 378 VE + L PE +N GG G P Sbjct: 318 ICLIQAVEAVGLCPEGKGGEFMETAYNEMLNNGGVLDPSKFPINTHGGLQCFGAP 372 >4EWP-A nrPDB Length = 350 Score = 51.5 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 45/130 (34%), Gaps = 2/130 (1%) Query: 45 RTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIA 104 RT I R ++T P + L+ L+ L + V V P A A + Sbjct: 47 RTGIVTRQRATAEETVPV-MAVGAAREALERAGLQGSDLDAVIVSTVTFPHATPSAAALV 105 Query: 105 QFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNI 164 P V+ C+ VA +R+G+ + GVE +S +I Sbjct: 106 AHEIG-ATPAPAYDVSAACAGYCYGVAQADALVRSGTARHVLVVGVERLSDVVDPTDRSI 164 Query: 165 TSRLMEKEKA 174 + L + A Sbjct: 165 SFLLGDGAGA 174 Score = 29.5 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 39/104 (37%), Gaps = 8/104 (7%) Query: 322 AYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGC 381 A AL AG+ D+ F ++A ++L+LP V A A G Sbjct: 252 AKVAREALDAAGVEPEDLAAFIPHQANMRIIDEFAKQLKLPESVVVARDIADA-----GN 306 Query: 382 TGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA---AAVFEYP 422 T A + ++ L G +++ IG G G A V P Sbjct: 307 TSAASIPLAMHRLLEENPELSGGLALQIGFGAGLVYGAQVVRLP 350 >3O04-A nrPDB Length = 413 Score = 50.3 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 24/123 (19%) Query: 278 VSDGAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKA 332 + +GA ++L A+ G I + Y G P G G A A+ +A+ A Sbjct: 231 IGEGAGIVILEEYEHAKARGAKIYAEIVGYGATGDAYHITAPAPNGEGAARAMKMAIDDA 290 Query: 333 GLTVSDVDIFEI-------NEAFASQAAYCV-----EKLRLPPEKVNPLGGAVALGHPLG 380 GLT VD N+ + +QA V +KL + K GH LG Sbjct: 291 GLTPDKVDYINAHGTSTPYNDEYETQAIKTVFGEHAKKLAISSTKSMT-------GHTLG 343 Query: 381 CTG 383 +G Sbjct: 344 ASG 346 >4QAV-A nrPDB Length = 415 Score = 47.3 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 37/114 (32%), Gaps = 8/114 (7%) Query: 278 VSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMG---IGPAYAIPVALQKAGL 334 + +GA ++L A++ G I + + + I GPA A+ AL+ AG+ Sbjct: 233 IGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGPALAVTRALKDAGI 292 Query: 335 TVSDVDIFEINEAFASQAAYCV-----EKLRLPPEKVNPLGGAVALGHPLGCTG 383 DVD + K GH LG G Sbjct: 293 NPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAG 346 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 47/133 (35%), Gaps = 13/133 (9%) Query: 29 GAPQASAADVVV---VHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQL-- 83 A +A DV + + AI +G ++ D + + + + L ++ Sbjct: 64 SAKEARRMDVFIHYGIAAALQAIADSGLDDVENLDKDRIGVNIGSGI---GGLPSIEVTG 120 Query: 84 GDICVGNVLQPGAGAIMARIAQFLSDIP-----ETVPLSTVNRQCSSGLQAVASIAGGIR 138 + G + I + +S P + C++G A+ + A I+ Sbjct: 121 KAVIEGGARKINPFFIPGSLINLISGHVTILKGYRGPSYGMVSACTTGAHAIGNSARLIK 180 Query: 139 NGSYDIGMACGVE 151 G DI +A G E Sbjct: 181 YGDADIMVAGGAE 193 >4R8E-A nrPDB Length = 413 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 39/117 (33%), Gaps = 10/117 (8%) Query: 278 VSDGAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKA 332 + DGA ++L A++ G I + + + P G G A A+ AL+ A Sbjct: 232 LGDGAGMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDA 291 Query: 333 GLTVSDVDIFEINEAFASQAA-----YCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 G+T S + + KV GH LG GA Sbjct: 292 GITTSQIGYINAHGTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMTGHLLGAAGA 348 Score = 38.0 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLM 169 P ++ C+SG+ + A I D+ +A G E S G G +R + Sbjct: 156 PSISIATACTSGVHNIGHAARIIAYNDADVMVAGGAEKAST-PLGVGGFGAARAL 209 >2GP6-A nrPDB Length = 434 Score = 46.5 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 33/118 (27%), Positives = 45/118 (38%), Gaps = 20/118 (16%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVG-----VPPDIMGIGPAYAIPVALQKAGLT 335 G A +L+ A+ G IL + ++ V PD G +AI A+Q AGL Sbjct: 259 GGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGLA 318 Query: 336 VSDVDIFEINEAFASQA-AYCVEKLRLPPEKVNPLGG---AV-----ALGHPLGCTGA 384 D+D + + N LGG AV ALGH +G GA Sbjct: 319 PGDIDHVNAHATGTQVGDLAEGRAIN------NALGGNRPAVYAPKSALGHSVGAVGA 370 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 26/70 (37%), Gaps = 6/70 (8%) Query: 82 QLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGS 141 + + V + GA A + + + V C+SG +A+A I G Sbjct: 152 AVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSA------CASGAEAIARAWQQIVLGE 205 Query: 142 YDIGMACGVE 151 D + GVE Sbjct: 206 ADAAICGGVE 215 >1J3N-A nrPDB Length = 408 Score = 46.5 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 36/114 (31%), Gaps = 10/114 (8%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKAGLT 335 GA ++L A++ G I L + P G G A A+ AL+ AG+ Sbjct: 232 GAGVLVLEAYEHAKKRGARIYAELVGFGRSADAHHITEPHPEGKGAALAMARALKDAGIA 291 Query: 336 VSDVDIFEINEAFASQA-----AYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 V + +++ +GH LG GA Sbjct: 292 PEQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMVSSTKSMIGHLLGAAGA 345 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 42/114 (36%), Gaps = 28/114 (24%) Query: 67 AVMTAVLKDVNLRPEQLGDICVGNVLQPGAG--------------------------AIM 100 L+D L+PE L VG ++ G G ++ Sbjct: 77 IAAQLALEDAGLKPEDLDPERVGTLVGTGIGGMETWEAQSRVFLERGPNRISPFFIPMMI 136 Query: 101 ARIAQFLSDIPE--TVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 A +A + T P STV C++G A+ S I+ G D+ +A G E+ Sbjct: 137 ANMASAHIAMRYGFTGPSSTVVTACATGADALGSALRMIQLGEADLVLAGGTEA 190 Score = 27.6 bits (60), Expect = 9.6, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 23/59 (38%), Gaps = 13/59 (22%) Query: 282 AAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVD 340 AA + + + + L L YA++ A +AL+ AGL D+D Sbjct: 49 AAEVDVDPGAYLDRKELRRLDRFVQYALI-------------AAQLALEDAGLKPEDLD 94 >5W2O-A nrPDB Length = 439 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 6/72 (8%) Query: 80 PEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRN 139 P ++ + V ++ GA A++ + + V CSSG +A+A I Sbjct: 157 PRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSA------CSSGSEAIAHAWRQIVM 210 Query: 140 GSYDIGMACGVE 151 G D+ + GVE Sbjct: 211 GDADVAVCGGVE 222 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 37/175 (21%), Positives = 60/175 (34%), Gaps = 38/175 (21%) Query: 225 PVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAA 284 P+ R+++ DE R S + +DG + A Sbjct: 224 PIEALPIAAFSMMRAMSTRNDEPERASRPFDK--------DRDGFV-------FGEAGAL 268 Query: 285 ILLARRSKAEELGLPILGVLRSYAVVG-----VPPDIMGIGPAYAIPVALQKAGLTVSDV 339 +L+ A+ G L L + V P G+ A+ +L+ AGL+ +D+ Sbjct: 269 MLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADI 328 Query: 340 DIFEIN----------EAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 D + EA A + A C + P+ ALGH +G GA Sbjct: 329 DHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKS--------ALGHSIGAVGA 375 >3E60-A nrPDB Length = 424 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 23/59 (38%), Gaps = 5/59 (8%) Query: 99 IMARIAQFLSDIPETV-----PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 I R+ S P +V CS+G A+ A I G D+ +A G ES Sbjct: 145 IPGRLINLASGYVSIKYGLRGPNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTES 203 Score = 43.8 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 43/106 (40%), Gaps = 9/106 (8%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKAGLT 335 GAA ++L A++ G I + Y + G P G G ++ AL++A + Sbjct: 246 GAAIVVLEELEHAKKRGARIYAEIIGYGLSGDAYHITAPSESGEGAQRSMMAALKRAQVN 305 Query: 336 VSDVDIFEINE----AFASQAAYCVEKLRLPPEKVNPLGGAVALGH 377 VS++D + A + A L +V+ ++GH Sbjct: 306 VSELDYINAHGTSTMADVIELAAVERVLGYYAPQVSMSSTKSSIGH 351 >4DFE-A nrPDB Length = 333 Score = 45.0 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 34/99 (34%) Query: 58 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS 117 D T +L ++ ++ P+ + I V A + Q I Sbjct: 62 DVTTSDLAFIASQRAIEAADIDPQSIDLIIVATSTPDFVFPSTACLLQNKLGIRNHGAAF 121 Query: 118 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 V CS AVA+ IR+G + + G E+ S Sbjct: 122 DVQAVCSGFAYAVATADSFIRSGQHRTALVIGAETFSRI 160 Score = 28.4 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 39/170 (22%), Positives = 57/170 (33%), Gaps = 34/170 (20%) Query: 260 LKPAFKKDGST-----TAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPP 314 L A DGS T GN + +A L +L + +L + Sbjct: 190 LASALHADGSHSNILCTPGNVNGGVVSGSAFLHMDGQAVFKLAVNVLEKV---------- 239 Query: 315 DIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVA 374 AL+KA L+ +D ++A KL LP E++ G Sbjct: 240 ----------AVEALEKANLSAEQIDWLIPHQANIRIMQSTCRKLGLPQERMIVTVGE-- 287 Query: 375 LGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA---AAVFEY 421 H G T A + L+ R G+ G + G G G A+V Y Sbjct: 288 --H--GNTSAASIPLALDVAVRDGRIKRGQNVLIEGVGGGFTWGASVIRY 333 >3KZU-A nrPDB Length = 428 Score = 45.0 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 5/59 (8%) Query: 99 IMARIAQFLSDIPETV-----PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 I R+ S P +V C++G A+ A I G D+ +A G ES Sbjct: 149 IPGRLINLASGHVSIKHKLRGPNHSVVTACATGTHAIGDAARLIAFGDADVMVAGGTES 207 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 37/106 (34%), Gaps = 9/106 (8%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKAGLT 335 GA ++L A G I + Y + G P G G + AL++AG+ Sbjct: 250 GAGIVVLEELEHALARGAKIYAEVIGYGMSGDAFHITAPTESGEGAQRCMVAALKRAGIV 309 Query: 336 VSDVDIFEINE----AFASQAAYCVEKLRLPPEKVNPLGGAVALGH 377 ++D + A + + K++ ++GH Sbjct: 310 PDEIDYINAHGTSTMADTIELGAVERVVGEAAAKISMSSTKSSIGH 355 >2IX4-A nrPDB Length = 431 Score = 45.0 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 42/119 (35%), Gaps = 12/119 (10%) Query: 278 VSDGAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKA 332 + +G+ I+L A+ G I L Y + G P G G A+ AL+++ Sbjct: 248 IGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPEDGKGAVLAMTRALRQS 307 Query: 333 GLTVSDVDIFEINEAFASQAAYCV-EKLRLPPEKVNPLGGAV------ALGHPLGCTGA 384 GL + +D + ++ + G A GH LG GA Sbjct: 308 GLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKGATGHLLGAAGA 366 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 122 QCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 C++G ++ I+ G D+ +A G ES Sbjct: 178 ACATGAHSIGDATRMIQFGDADVMVAGGTES 208 >4LS7-A nrPDB Length = 426 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 13/101 (12%) Query: 251 STTMEGLAKLKPAFK-KDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAV 309 ST + +P K +DG + +GA I+L A G I G + Y Sbjct: 223 STNPDPKTASRPFDKNRDGFV-------MGEGAGIIVLEELEHALARGAKIYGEIVGYGS 275 Query: 310 VGVP-----PDIMGIGPAYAIPVALQKAGLTVSDVDIFEIN 345 G P G G A A+ A++ AG+ ++D + Sbjct: 276 TGDAYHITAPAQDGEGGARAMQEAIKDAGIAPEEIDYINAH 316 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 23/55 (41%), Gaps = 5/55 (9%) Query: 108 SDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES----MSLADR 158 + + V TV C++G ++ I+ G D+ + G E+ MS A Sbjct: 163 ALGAKGVNSCTVT-ACATGTNSIGDAFKVIQRGDADVMVTGGTEAPLTRMSFAGF 216 >2EBD-A nrPDB Length = 309 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 40/102 (39%), Gaps = 5/102 (4%) Query: 57 KDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMA--RIAQFLSDIPETV 114 K+ T + + L++ NL PE+L I + + A AQ + + V Sbjct: 46 KEETITYMATQAAKEALREANLSPEELDLIILATLTPQKRFPSTACLVQAQLKA---KGV 102 Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 ++ CS + A+ I++G + G E +S A Sbjct: 103 YAFDISAACSGFIYALDIADSFIKSGKAKNVLVIGAEKLSEA 144 Score = 36.9 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 9/99 (9%) Query: 326 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 L+KAG+ +V + ++A EKL +P EKV + G T A Sbjct: 217 REVLEKAGVKPEEVSLVIPHQANVRIINALAEKLNIPKEKVFVN---IQK---YGNTSAA 270 Query: 386 QVITLLNELKRRGKRAYG---VVSMCIGTGMGAAAVFEY 421 + L+E + GK G +++ G A + Y Sbjct: 271 SIPIALHEAIKEGKVKRGDLILMTAMGGGLTWGAVLLRY 309 >4X0O-A nrPDB Length = 362 Score = 43.8 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 31/96 (32%), Gaps = 1/96 (1%) Query: 59 TTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLST 118 +L + + + E++ I V +A Q IP + Sbjct: 50 VNTSDLATVAAQHAIACAGVSVEEIDLIIVATCSPDSLIPNIASRVQQNLGIP-SAAAFD 108 Query: 119 VNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS 154 +N C+ L + + ++ Y + G E +S Sbjct: 109 LNAACTGFLYGLETATRLMQASHYRHALVIGAERLS 144 >1OXH-A nrPDB Length = 430 Score = 43.4 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 45/130 (34%), Gaps = 23/130 (17%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKAGLT 335 G+ ++L AE+ G IL + Y P G G AI +AL++A ++ Sbjct: 253 GSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEGQGAIKAIKLALEEAEIS 312 Query: 336 VSDVDIFEIN----------EAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 385 V + E+ A A E V GH LG GA Sbjct: 313 PEQVAYVNAHGTSTPANEKGESGAIVAVLGKE--------VPVSSTKSFTGHLLGAAGAV 364 Query: 386 QVITLLNELK 395 + I + ++ Sbjct: 365 EAIVTIEAMR 374 Score = 41.5 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 36/183 (19%), Positives = 64/183 (34%), Gaps = 22/183 (12%) Query: 116 LSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPG-NITSRLMEKEKA 174 ++N CSS A+ I+ G D+ + G E+ S+ G + L E Sbjct: 176 CKSINTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEA-SITPFAIAGFQALTALSTTEDP 234 Query: 175 RDCLIPMGITSENVAERFGISREKQDTFALASQQKAAR------AQSKGCFQA-EIVPVT 227 IP + G E L S + A + A+ G + +T Sbjct: 235 TRASIPFDK--DRNGFVMG---EGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMT 289 Query: 228 TTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILL 287 + + +G ++I + +E + E +A G++T N S GA +L Sbjct: 290 SPHPEGQGAIKAIKLALEE---AEISPEQVA----YVNAHGTSTPANEKGES-GAIVAVL 341 Query: 288 ARR 290 + Sbjct: 342 GKE 344 >4JPF-A nrPDB Length = 436 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 5/73 (6%) Query: 278 VSDGAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKA 332 +SDG+ A++L A G I L + + G P G G A + AL+ A Sbjct: 254 LSDGSGALVLEELEHARARGARIYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDA 313 Query: 333 GLTVSDVDIFEIN 345 GL VD + Sbjct: 314 GLDPRQVDYINAH 326 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 17/37 (45%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 P + C++G ++ A I G D+ +A G E Sbjct: 178 PNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSE 214 >4YUC-A nrPDB Length = 335 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 27/83 (32%), Gaps = 3/83 (3%) Query: 55 GFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC--VGNVLQPGAGAIMARIAQFLSDIPE 112 KD T + + ++D L+ E + I G+ Q + Sbjct: 52 WVKDETASFMGAEAAKEAVRDAGLKLEDIDLIINASGSPEQAVPDGGPLVQRELGLGRS- 110 Query: 113 TVPLSTVNRQCSSGLQAVASIAG 135 VP TVN C S A+ A Sbjct: 111 GVPSITVNASCLSFFVALDVAAN 133 Score = 28.4 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 13/21 (61%) Query: 322 AYAIPVALQKAGLTVSDVDIF 342 A A A++ AGL + D+D+ Sbjct: 63 AEAAKEAVRDAGLKLEDIDLI 83 >5BY7-A nrPDB Length = 360 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 32/90 (35%), Gaps = 1/90 (1%) Query: 60 TPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTV 119 T +L + L + PE++ + +G A + I + VP + Sbjct: 80 TLADLAHQAGSRALDAAGVTPEEVDLVVLGTATPDRLMPTTATVVADRLGI-DGVPAYQL 138 Query: 120 NRQCSSGLQAVASIAGGIRNGSYDIGMACG 149 CS +QA+A + G+ + G Sbjct: 139 QSGCSGAVQALAVTRSLLLGGTARTALVLG 168 >2GQD-A nrPDB Length = 437 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 34/113 (30%), Gaps = 10/113 (8%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGVP-----PDIMGIGPAYAIPVALQKAGLT 335 GA +++ A+ G I + Y G P G G + A+ A+ AG+ Sbjct: 258 GAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIE 317 Query: 336 VSDVDIFEINEAFASQAA-----YCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 DV + + + GH LG TG Sbjct: 318 PKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATG 370 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 7/47 (14%), Positives = 18/47 (38%), Gaps = 4/47 (8%) Query: 106 FLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 + P ++ C++G ++ ++ G D + G E+ Sbjct: 175 LGAKGPNGATVT----ACATGTNSIGEAFKIVQRGDADAMITGGTEA 217 Score = 27.6 bits (60), Expect = 9.7, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 13/33 (39%), Gaps = 4/33 (12%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVH-GRRTAIC 49 G +P+ + L + VV+ G + I Sbjct: 13 GLVPRGSHMLEMSQN---KRVVITGMGALSPIG 42 >4DDO-A nrPDB Length = 451 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 38/117 (32%), Gaps = 17/117 (14%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAY------AIPVALQKAGL 334 GAA +++ A G + + Y M GP A+ +AL+ + Sbjct: 265 GAAMVVVESLDHALARGARPIAEIIGYGTTA-DAYHMTAGPDDGSGAMRAMKLALRMGDV 323 Query: 335 TVSDVDIFEIN-------EAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 384 VD + +A +A V + P A GH LG GA Sbjct: 324 APEQVDYVNAHATSTPVGDAGEIEALKTVFGVGAGPA---ISSTKSATGHLLGAAGA 377 Score = 38.4 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 17/31 (54%) Query: 122 QCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 C++ +QA+ IR G D+ +A G E+ Sbjct: 192 ACAASVQAIGDAMRMIRTGEADVVLAGGAEA 222 >6QSP-A nrPDB Length = 406 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 1/90 (1%) Query: 110 IPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLM 169 + P T++ CSS +A+ S I G D + G +++S ++ S Sbjct: 161 LAIEGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMPINGFDSLESLSP 220 Query: 170 EKEKARDCLIPMGITSENVAERFGISREKQ 199 + C GIT + ++RE Q Sbjct: 221 TLCEPF-CQDRQGITIGEASTLLLLTREPQ 249 >4JGA-A nrPDB Length = 437 Score = 41.9 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 99 IMARIAQFLSDIPE-----TVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESM 153 I A + LS + + P T CS+G A+ I++G D+ +A G E+ Sbjct: 156 IPASLINLLSGLVSIKYGFSGPNQTAVTACSTGAHAIGDAMRMIKHGYADVMIAGGAEA- 214 Query: 154 SLADRGNPGNITSRLM 169 + G G + +R + Sbjct: 215 PVTPVGVAGFVAARAL 230 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 40/114 (35%), Gaps = 10/114 (8%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKAGLT 335 GA ++L A G + G + Y G P G G A+ A+ A +T Sbjct: 257 GAGVVVLEEYEHALNRGAKVYGEVIGYGSTGDAYHMTAPHPEGRGAYRAMRDAMLDATIT 316 Query: 336 VSDVDIFEINEAFA----SQAAYCVEKLRLPPE-KVNPLGGAVALGHPLGCTGA 384 +D + V+KL L KV ++GH LG G+ Sbjct: 317 PDMIDYINAHGTSTTLGDGIELAAVQKLFLEANPKVLMSSTKSSIGHLLGAAGS 370 >4RYB-A nrPDB Length = 320 Score = 41.5 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 27/85 (31%) Query: 77 NLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGG 136 L ++ I V A I Q I P V C+ + A+ + Sbjct: 68 GLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAY 127 Query: 137 IRNGSYDIGMACGVESMSLADRGNP 161 I++G + G E+ S N Sbjct: 128 IKSGMAKNALVIGAETFSRIVDWND 152 >1MZJ-A nrPDB Length = 339 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 43/131 (32%), Gaps = 2/131 (1%) Query: 44 RRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARI 103 RT I R+ R D T + A L+ + P ++ + V + + + Sbjct: 44 TRTGI-RSRRIAEPDETIQVMGVAASRRALEHAGVDPAEIDLVVV-STMTNFVHTPPLSV 101 Query: 104 AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGN 163 A + ++ C+ A++ A + +G + E M+ + Sbjct: 102 AIAHELGADNAGGFDLSAACAGFCHALSIAADAVESGGSRHVLVVATERMTDVIDLADRS 161 Query: 164 ITSRLMEKEKA 174 ++ + A Sbjct: 162 LSFLFGDGAGA 172 Score = 31.5 bits (70), Expect = 0.82, Method: Composition-based stats. Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 322 AYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGC 381 A AL+ AGLTV D+ F ++A V++L + PE V A G+ Sbjct: 234 VPAAREALEVAGLTVGDLVAFVPHQANLRIIDVLVDRLGV-PEHVVVSRDAEDTGN---- 288 Query: 382 TGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAA 416 T + V L+ L R G G ++ IG G G + Sbjct: 289 TSSASVALALDRLVRSGAVPGGGPALMIGFGAGLS 323 Score = 28.4 bits (62), Expect = 6.9, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 34/107 (31%), Gaps = 31/107 (28%) Query: 304 LRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPP 363 +RS + I +G A AL+ AG+ +++D+ + + PP Sbjct: 48 IRSRRIAEPDETIQVMG-VAASRRALEHAGVDPAEIDL--------VVVSTMTNFVHTPP 98 Query: 364 EKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIG 410 V A+ H LG + + + C G Sbjct: 99 LSV-------AIAHELGA---------------DNAGGFDLSAACAG 123 >4JRH-A nrPDB Length = 417 Score = 40.3 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 30/73 (41%), Gaps = 5/73 (6%) Query: 278 VSDGAAAILLARRSKAEELGLPILGVLRSYAVVGV-----PPDIMGIGPAYAIPVALQKA 332 + DGA ++L A+ G I + + + G P G G A A+ A++ A Sbjct: 235 LGDGAGIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDA 294 Query: 333 GLTVSDVDIFEIN 345 G+T + + Sbjct: 295 GVTGEQIGYVNAH 307 Score = 38.0 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLM 169 P ++ C++GL + A I G D +A G E S G G ++ + Sbjct: 159 PNIAISTACTTGLHNIGHAARMIAYGDADAMVAGGAEKAST-PLGMAGFGAAKAL 212 >4V2P-A nrPDB Length = 351 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 24/83 (28%), Gaps = 3/83 (3%) Query: 55 GFKDTTPDELLSAVMTAVLKDVNLRPEQLGDIC--VGNVLQPGAGAIMARIAQFLSDIPE 112 K T + + ++D L+ + I G+ Q + Sbjct: 68 WVKGETAAFMGAEAAKEAVRDAGLQLSDIDLIISASGSPQQAVPDGGPLVQRELGLGRS- 126 Query: 113 TVPLSTVNRQCSSGLQAVASIAG 135 P TVN C S A+ + Sbjct: 127 GTPAITVNASCLSFFVALEVASN 149 >4NHD-A nrPDB Length = 319 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 40/121 (33%), Gaps = 4/121 (3%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 +D +V RT I R R + T ++ + + + I V Sbjct: 31 TSDEWIV--ARTGI-RERRIAADNETVADMAFFAAQNAINMAGIDKHDIDMIIVATTSAS 87 Query: 95 GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS 154 A Q I + P + CS + A++ +++G + G +++S Sbjct: 88 HTFPSAACQVQGKLGI-KGCPAFDLAAACSGFMYALSIADQHVKSGMCKHVLVIGADALS 146 Query: 155 L 155 Sbjct: 147 K 147 >3H76-A nrPDB Length = 359 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 38/111 (34%), Gaps = 2/111 (1%) Query: 64 LLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQC 123 L+ ++ L PE + + V + A + Q L + +P+ + QC Sbjct: 77 LMVPAARQAIEAAGLLPEDIDLLLVNTLSPDHHDPSQACLIQPLLGL-RHIPVLDIRAQC 135 Query: 124 SSGLQAVASIAGGIRNGSYDIGMACGVESMS-LADRGNPGNITSRLMEKEK 173 S L + G I G + E +S D + G S L+ Sbjct: 136 SGLLYGLQMARGQILAGLARHVLVVCGEVLSKRMDCSDRGRNLSILLGDGA 186 Score = 33.4 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 13/24 (54%) Query: 322 AYAIPVALQKAGLTVSDVDIFEIN 345 A A++ AGL D+D+ +N Sbjct: 79 VPAARQAIEAAGLLPEDIDLLLVN 102 >6ESQ-I nrPDB Length = 349 Score = 38.4 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 57/187 (30%), Gaps = 12/187 (6%) Query: 64 LLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQC 123 + +K + E++G + VG+ P A + + + + C Sbjct: 55 IAVEAARNAVKRAGINAEKIGAVYVGSESHPYAVKPTSATVAEAIGATPDLTAADLEFAC 114 Query: 124 SSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGI 183 +G + G + +G + GMA G +G PG+ A I Sbjct: 115 KAGTAGIQMCMGLVGSGLIEYGMAIGA----DTAQGAPGDALEYTASAGGA--AYIIGNK 168 Query: 184 TSENVAE---RFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI 240 E +A + + + D + Q G F E ++ KG + Sbjct: 169 KDEMIAVFNGTYSYTTDTPDFWRREGQSYPKH---GGRFTGEPAYFKHVLNAAKGIMEKM 225 Query: 241 TVTQDEG 247 T + Sbjct: 226 GTTVKDY 232 >3IL7-A nrPDB Length = 313 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 16/114 (14%), Positives = 36/114 (31%), Gaps = 5/114 (4%) Query: 63 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQ--FLSDIPETVPLSTVN 120 +L + D ++PE + I V +A + Q + V Sbjct: 53 DLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTG---KVASMDQL 109 Query: 121 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKA 174 CS + ++ + +++G Y + G + +S + + A Sbjct: 110 AACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGA 163 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 8/68 (11%) Query: 316 IMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEK----VNPLGG 371 IMG A ++KA LT D+D+F ++A E+L + +K VN G Sbjct: 213 IMG----DASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGN 268 Query: 372 AVALGHPL 379 A PL Sbjct: 269 TSAASIPL 276 >3HO9-A nrPDB Length = 427 Score = 37.6 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLM 169 P ++ +SG+ + A I G D+ +A G E S G G +R + Sbjct: 170 PSISIATAATSGVHNIGHAARIIAYGDADVMVAGGAEKAST-PLGVGGFGAARAL 223 >4YLT-A nrPDB Length = 316 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 42/122 (34%), Gaps = 4/122 (3%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 +D +V RT I G +T + L+ + + +G I V Sbjct: 28 TSDEWIV--TRTGIRERRIAGLDETVAT-MGFQAAEKALEMAGIDKDDIGLIIVATTSSS 84 Query: 95 GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS 154 A A Q + I + + C+ A++ +++G+ + G + +S Sbjct: 85 HAFPSSACQVQRMLGI-KDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLS 143 Query: 155 LA 156 A Sbjct: 144 RA 145 Score = 34.2 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 6/63 (9%) Query: 304 LRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEI-----NEAFASQAAYCVEK 358 +R + G+ + +G A AL+ AG+ D+ + + + AF S A Sbjct: 39 IRERRIAGLDETVATMG-FQAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRM 97 Query: 359 LRL 361 L + Sbjct: 98 LGI 100 >2AJ9-A nrPDB Length = 356 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 34/107 (31%), Gaps = 2/107 (1%) Query: 58 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS 117 D + + + L + L + + V A S + + Sbjct: 79 DESAASMATEACRRALSNAGLSAADIDGVIV-TTNTHFLQTPPAAPMVAASLGAKGILGF 137 Query: 118 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS-LADRGNPGN 163 ++ C+ A+ + A IR G + G E +S D + GN Sbjct: 138 DLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDMYDAGN 184 Score = 34.6 bits (78), Expect = 0.093, Method: Composition-based stats. Identities = 46/194 (23%), Positives = 72/194 (37%), Gaps = 35/194 (18%) Query: 256 GLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLA--------------RRSKAEELGLPIL 301 G KL P AGN +DGAAA+++ +A+ + I Sbjct: 169 GTEKLSPTIDMYD---AGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDID 225 Query: 302 GVLRSYAVVGVPPDIMGIGPAY----------AIPVALQKAGLTVSDVDIFEINEAFASQ 351 + + G P + GPA A+ AG+ +D+F ++A + Sbjct: 226 WITFAQNPSGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRI 285 Query: 352 AAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGT 411 V+ L+L P+ V + H G T A + + EL G G +++ IG Sbjct: 286 NELLVKNLQLRPDAVVAN----DIEH-TGNTSAASIPLAMAELLTTGAAKPGDLALLIGY 340 Query: 412 GMG---AAAVFEYP 422 G G AA V P Sbjct: 341 GAGLSYAAQVVRMP 354 >5BQS-A nrPDB Length = 323 Score = 37.2 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 35/94 (37%), Gaps = 1/94 (1%) Query: 63 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ 122 +L + V ++ + ++L I + + A Q + Sbjct: 52 DLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIG-ANKAFAFDLTAA 110 Query: 123 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 CS + A+++ I +G + G+ G E++S A Sbjct: 111 CSGFVFALSTAEKFIASGRFQKGLVIGSETLSKA 144 >1UB7-A nrPDB Length = 322 Score = 36.9 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 16/46 (34%), Positives = 24/46 (52%) Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPL 369 A A++KAGLT D+ +F ++A E+L LP E+V Sbjct: 225 ATLEAIEKAGLTPEDIRLFVPHQANLRIIDAARERLGLPWERVAVN 270 Score = 31.5 bits (70), Expect = 0.76, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 39/122 (31%), Gaps = 5/122 (4%) Query: 35 AADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQP 94 +D +V RT I + R +D +L + +L+ E + + V Sbjct: 27 TSDEWIV--TRTGI-KERRVAAEDEYTSDLAFKAVEDLLRRHPGALEGVDAVIVATNTPD 83 Query: 95 GAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS 154 A A + + C + A+A + G +A G E++S Sbjct: 84 ALFPDTA--ALVQARFGLKAFAYDLLAGCPGWIYALAQAHALVEAGLAQKVLAVGAEALS 141 Query: 155 LA 156 Sbjct: 142 KI 143 >4JD3-A nrPDB Length = 353 Score = 36.9 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 35/138 (25%), Positives = 50/138 (36%), Gaps = 13/138 (9%) Query: 60 TPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTV 119 +L + L D NLRP + I V ++ ARIA L P+ V Sbjct: 75 KAVDLGVEALLGALDDANLRPSDIDMIATATVTGVAVPSLDARIAGRLGLRPD------V 128 Query: 120 NRQCSSGLQAVASIAGGIRNGSY------DIGMACGVESMSLADRGNPGNITSRLMEKEK 173 R GL +VA AG R Y D+ + VE SL ++S L+ Sbjct: 129 RRMPLFGLGSVAGAAGVARLRDYLRGAPDDVAVLVSVELCSLTYPAVKPTVSS-LVGTAL 187 Query: 174 ARDCLIPMGITSENVAER 191 D + + AE+ Sbjct: 188 FGDGAAAVVAVGDRRAEQ 205 >3IL4-A nrPDB Length = 320 Score = 36.5 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 34/94 (36%), Gaps = 1/94 (1%) Query: 63 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ 122 +L V +L+ + ++ I V V +A Q + ++ Sbjct: 53 DLCHQVAKQLLEKSGKQASEIDFILVATVTPDFNMPSVACQVQ-GAIGATEAFAFDISAA 111 Query: 123 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 156 CS + A++ + +G Y G+ G E+ S Sbjct: 112 CSGFVYALSMAEKLVLSGRYQTGLVIGGETFSKM 145 >2IWZ-A nrPDB Length = 438 Score = 36.5 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 39/114 (34%), Gaps = 10/114 (8%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGVP-----PDIMGIGPAYAIPVALQKAGLT 335 GAA ++L A + I + Y + G PD G G + AL+ AG+ Sbjct: 258 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 317 Query: 336 VSDVDIFEINEAFA----SQAAYCVEKLRLPPE-KVNPLGGAVALGHPLGCTGA 384 ++ + + ++ L + A GH LG GA Sbjct: 318 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 371 Score = 35.7 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 P V+ C++G AV I +G D+ +A G +S Sbjct: 180 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 217 >5ENY-A nrPDB Length = 764 Score = 36.1 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 49/155 (31%), Gaps = 27/155 (17%) Query: 72 VLKDVNLRPEQLGD----ICVGNVLQPGAGAIMARI----------AQFLSDIPE----T 113 +D L + + +G ++ G ++ R A + IP Sbjct: 274 AFEDAGYNARTLNEKKCGVYLG-IMSNEYGVMLNRQSRANATGNSFAIAAARIPYFLNLK 332 Query: 114 VPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGV------ES-MSLADRGNPGNITS 166 P ++ CSS L + N D+ + GV ES MS+ + G Sbjct: 333 GPAIPIDTACSSSLVGTHLARQALINKEIDMALVGGVSLYLTPESYMSMCEAGMLSP-DG 391 Query: 167 RLMEKEKARDCLIPMGITSENVAERFGISREKQDT 201 + + + +P V +R + +D Sbjct: 392 QCKAFDNGANGFVPGEGAGALVLKRLKDAEADRDH 426 >6ET0-A nrPDB Length = 365 Score = 34.9 bits (79), Expect = 0.067, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 35/99 (35%), Gaps = 16/99 (16%) Query: 324 AIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTG 383 A+ AL+KAGL D+D F ++ E + PE+ +G TG Sbjct: 265 AMRRALEKAGLGSDDIDYFVFHQPAPFLVKAWAEGIGARPEQYQLT---------MGDTG 315 Query: 384 ARQ-------VITLLNELKRRGKRAYGVVSMCIGTGMGA 415 ++T L E K R + G G A Sbjct: 316 VMISVSIPYTLMTGLREGKIRPGDRIVMAGAATGWGFAA 354 >4XOX-A nrPDB Length = 404 Score = 34.9 bits (79), Expect = 0.071, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 35/119 (29%), Gaps = 28/119 (23%) Query: 61 PDELLSAVMTAVLKDVNLRPEQLG----DICVGNVLQPGAGAIMA----RIAQFLSDIPE 112 + + D L PEQ+ I G+ ++A R P Sbjct: 71 AAAYAYLSLEQAIADAGLTPEQVSNDRTGIVAGSGGASSENQVIAVDTQREKGVKRVGPY 130 Query: 113 TVPLS--------------------TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 VP + +++ C++ + + I+ G DI A G E Sbjct: 131 MVPRTMSSTVSACLATPFKIRGVNYSISSACATSAHCIGNAVELIQLGKQDIVFAGGGE 189 >5BNS-A nrPDB Length = 317 Score = 34.6 bits (78), Expect = 0.082, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 36/98 (36%), Gaps = 1/98 (1%) Query: 58 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS 117 + T + T ++ + +Q+G I V A A Q + I + P Sbjct: 48 NETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGI-KGCPAF 106 Query: 118 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSL 155 V C+ A++ +++G+ + G + ++ Sbjct: 107 DVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLAR 144 >4EFI-A nrPDB Length = 354 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 35/96 (36%), Gaps = 5/96 (5%) Query: 57 KDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLS--DIPETV 114 T+ +L +L + + + + + V Q + A + D+P + Sbjct: 62 AQTSAGDLCRKAGEKLLAGLGWQADSIDALIF--VSQTPNYRLPATAFVLQAELDLPASC 119 Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYD-IGMACG 149 +N CS QA+ I+ G+ + +A G Sbjct: 120 LALDINLGCSGYPQALWLGMNLIQTGAAKRVLLAVG 155 >1TQY-A nrPDB Length = 424 Score = 34.2 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 43/208 (20%), Positives = 69/208 (33%), Gaps = 30/208 (14%) Query: 203 ALASQQKAARAQSKGCFQ-----AEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGL 257 L S A RA +G A P+T V R+ T D+ S +G Sbjct: 172 GLDSVGNAVRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHASRPFDG- 230 Query: 258 AKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIM 317 +DG +++GAA +L A G I + YA + Sbjct: 231 -------TRDGFV-------LAEGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMT 276 Query: 318 GIGP-----AYAIPVALQKAGLTVSDVDIFEINEAFASQ-----AAYCVEKLRLPPEKVN 367 G+ A I VAL ++ +D+D + + Q A L + Sbjct: 277 GLKADGREMAETIRVALDESRTDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTP 336 Query: 368 PLGGAVALGHPLGCTGARQVITLLNELK 395 +GH LG G+ ++ + L+ Sbjct: 337 VSSIKSMVGHSLGAIGSLEIAACVLALE 364 Score = 33.0 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 19/34 (55%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMAC 148 P++ V+ C+SGL +V + I GS D+ A Sbjct: 161 PVTMVSTGCTSGLDSVGNAVRAIEEGSADVMFAG 194 >4OQJ-A nrPDB Length = 845 Score = 34.2 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 15/34 (44%) Query: 115 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMAC 148 P + N CS+ L AV + +G + +A Sbjct: 185 PSVSTNTACSTSLVAVHLACLSLLSGDCTMALAG 218 >5YO9-A nrPDB Length = 371 Score = 33.8 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 11/85 (12%), Positives = 27/85 (31%), Gaps = 2/85 (2%) Query: 63 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ 122 E +++ + E + + + A A + S + +N Sbjct: 100 EWGVIAAKQAMENAGVTAEDIDVVILAC--SNMQRAYPAVAIEIQSALGIQGYAYDMNVA 157 Query: 123 CSSGLQAVASIAGGIRNGSYDIGMA 147 S+ + A IR+G+ + + Sbjct: 158 ASAATFGLKQAADAIRSGARRVLLV 182 Score = 31.1 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 11/78 (14%) Query: 322 AYAIPVALQKAGLTVSDVDIF-----EINEAFASQAAYCVEKLRLP--PEKVNPLGGAVA 374 A A++ AG+T D+D+ + A+ + A L + +N A Sbjct: 103 VIAAKQAMENAGVTAEDIDVVILACSNMQRAYPAVAIEIQSALGIQGYAYDMNVAASAAT 162 Query: 375 LGHPLGC----TGARQVI 388 G +GAR+V+ Sbjct: 163 FGLKQAADAIRSGARRVL 180 >3UBR-A nrPDB Length = 439 Score = 33.0 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 28/55 (50%), Gaps = 5/55 (9%) Query: 182 GITSENVAE--RFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDK 234 G+T+E A+ + E+Q + + +AA+A G +AE+ P+ T + + Sbjct: 289 GVTNERKAKVKEMKLKAEEQ---LVKAHFEAAKAWELGATEAEMKPILTDIRHAQ 340 >1E5M-A nrPDB Length = 416 Score = 33.0 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 25/64 (39%), Gaps = 5/64 (7%) Query: 106 FLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNIT 165 + P ++ C++G A+ ++NG + G E+ ++ G + Sbjct: 154 LGAKGPNNCTVT----ACAAGSNAIGDAFRLVQNGYAKAMICGGTEA-AITPLSYAGFAS 208 Query: 166 SRLM 169 +R + Sbjct: 209 ARAL 212 Score = 30.3 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 26/70 (37%), Gaps = 5/70 (7%) Query: 281 GAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIM-----GIGPAYAIPVALQKAGLT 335 G+ ++L A G I G + YA+ I G G AI AL+ +GL Sbjct: 238 GSGILILEELESALARGAKIYGEMVGYAMTCDAYHITAPVPDGRGATRAIAWALKDSGLK 297 Query: 336 VSDVDIFEIN 345 V + Sbjct: 298 PEMVSYINAH 307 >5L9W-B nrPDB Length = 732 Score = 32.6 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 54/162 (33%), Gaps = 24/162 (14%) Query: 13 GPADSGWMPQAAPCLS---GAPQASAADVVV-------VHGRRTAICRAG-RGGFKDTTP 61 GP +G MP C P + ADVV+ +G R + +A ++ Sbjct: 368 GPRSAGSMP-GPVCYDLGGTEPTVTDADVVLGYINPDTYYGGRMPLNKAKAEKAIREKIA 426 Query: 62 DELLSAVMTAV-----LKDVNLRPEQLGDICV-GN-----VLQPGAGAIMARIAQFLSDI 110 L + A + D N+ ++ + G VL GA +A DI Sbjct: 427 QPLGIETIEAAALIRYIVDENMASAIKREVHMRGYHPEDFVLFAFGGAGPTHMAGLKGDI 486 Query: 111 PETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152 P+ V C+ G ++ I + M G E Sbjct: 487 PKAVVFPAAPVFCAMGS-SIMDIVHMYEQSRRMVFMEPGTEK 527 >5GW4-d nrPDB Length = 528 Score = 32.6 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 31/84 (36%), Gaps = 10/84 (11%) Query: 234 KGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAIL------L 287 K ++ I ++ D T ++ +A L P + +A S+ DG +++ L Sbjct: 49 KTSRGEIIISNDGH----TILKQMAILHPVARMLVEVSAAQDSEAGDGTTSVVILTGALL 104 Query: 288 ARRSKAEELGLPILGVLRSYAVVG 311 + G+ + S+ Sbjct: 105 GAAERLLNKGIHPTIIADSFQSAA 128 >2P1R-A nrPDB Length = 299 Score = 32.2 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 20/141 (14%) Query: 219 FQAEIVPVTTTVHDDKGTKRSITVTQDEGIR--PSTTMEGLAKLKPA-----FKKDGSTT 271 F A ++ + D++ + +IT+ +DEGI+ T E + + Sbjct: 4 FPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIA 63 Query: 272 AGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQK 331 G +++ + A++ R A LGL LG +A P+ A+ AL+ Sbjct: 64 GGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPE--------ALDKALKL 115 Query: 332 --AGLTVSDVDIFEINE--AF 348 AG + +D+ +N+ F Sbjct: 116 AIAGNAME-IDMAMVNDKTCF 135 >2BZ4-A nrPDB Length = 418 Score = 32.2 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 18/48 (37%) Query: 104 AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 A + +++ C++ + + I+ G DI A G E Sbjct: 156 ACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGE 203 >3GGO-A nrPDB Length = 314 Score = 31.9 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 22/73 (30%), Gaps = 13/73 (17%) Query: 18 GWMPQAAPC---LSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLK 74 G +P+ + + S +V++V G F L + + Sbjct: 13 GLVPRGSHMKNIIKILKSLSMQNVLIVG------VGFMGGSF----AKSLRRSGFKGKIY 62 Query: 75 DVNLRPEQLGDIC 87 ++ PE + Sbjct: 63 GYDINPESISKAV 75 >1TQY-B nrPDB Length = 415 Score = 31.5 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 25/77 (32%), Gaps = 4/77 (5%) Query: 68 VMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQF---LSDIPETVPLSTVNRQ-C 123 + L D PE + + P A AR +P TVP +T R Sbjct: 284 AIRLALNDAGTGPEDVDVVFADGAGVPELDAAEARAIGRVFGREGVPVTVPKTTTGRLYS 343 Query: 124 SSGLQAVASIAGGIRNG 140 G V + +R G Sbjct: 344 GGGPLDVVTALMSLREG 360 >6CTD-A nrPDB Length = 121 Score = 31.1 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 23/64 (35%), Gaps = 5/64 (7%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVN 77 G +P+ + L G + A +V I A T +++T ++ + Sbjct: 13 GLVPRGSHMLKGFKEFLARGNIVDLAVAVVIGTAFTALVTKFT-----DSIITPLINRIG 67 Query: 78 LRPE 81 + + Sbjct: 68 VNAQ 71 >5LBT-A nrPDB Length = 237 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 22/58 (37%), Gaps = 5/58 (8%) Query: 36 ADVVVVHGRRTAICRAGRGGFKDTTPDEL---LSAVMTAVLKDVNLRPEQLGDICVGN 90 V++V+ + ++ G K+ DEL V + L +NL P G Sbjct: 4 KKVLIVYAHQEP--KSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGT 59 >6G2J-R nrPDB Length = 116 Score = 30.3 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%) Query: 343 EINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHP 378 E+NE FA + + GG ALGHP Sbjct: 54 EVNENFAIDLIAQQPVNEVEHRIIACDGGGGALGHP 89 >5MB9-A nrPDB Length = 590 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 28/74 (37%), Gaps = 10/74 (13%) Query: 68 VMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQ-FLSDIPETV----PLSTVNRQ 122 ++ + +K L P + ++ + G + RIA F PE+ P + + Sbjct: 342 LVESAVKKAGLDPLDVDEVIM-----SGGTSNTPRIAANFRYIFPESTRILAPSTDPSAL 396 Query: 123 CSSGLQAVASIAGG 136 S LQA + Sbjct: 397 NPSELQARGAALQA 410 >5VXG-A nrPDB Length = 358 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 9/96 (9%) Query: 323 YAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHP-LGC 381 A L G V ++D F I++ A V+ + P KV + G H +G Sbjct: 266 VAAKQVL---GWAVEELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGE----HGNIGP 318 Query: 382 TGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAA 417 V++ L EL R K + + IG+G+ + Sbjct: 319 ASVPIVLSKLKELGRLKKGDR-IALLGIGSGLNCSM 353 >4ZCK-A nrPDB Length = 332 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 25/73 (34%), Gaps = 7/73 (9%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVH----GRRTAICRAGRGGFKDTTPDELLSAVMTAVL 73 G +P+ + S V + C G F T ++L + ++ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSTVSMFFCVNTSPFCG-KEGKF--VTSRQILDRLNKELV 69 Query: 74 KDVNLRPEQLGDI 86 +V LR E+ D Sbjct: 70 HNVALRVEETEDA 82 >4JN4-A nrPDB Length = 608 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 9/100 (9%) Query: 242 VTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI- 300 +D+GI + +LK A +K +S+Q +D + A + + + + + Sbjct: 244 FKKDQGIDLRNDPLAMQRLKEAAEKAKI--ELSSAQQTDVNLPYITADATGPKHMNIKVT 301 Query: 301 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVD 340 L S V I + VALQ AGL+VSD+D Sbjct: 302 RAKLESLVEDLVNRSIEPL------KVALQDAGLSVSDID 335 >3OYT-A nrPDB Length = 410 Score = 29.9 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 17/48 (35%) Query: 104 AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 A + +++ C++ + I+ G DI A G E Sbjct: 148 ACLATPFKIKGVNYSISSACATSAHCIGHALELIQLGKQDIVFAGGGE 195 >2Z0I-A nrPDB Length = 330 Score = 29.9 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 42/119 (35%), Gaps = 24/119 (20%) Query: 228 TTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGS---------TTAGNSSQV 278 K + S ++D S T+E + L+ F T+ G+ + Sbjct: 81 VPSRVPKDEQGSAADSED-----SPTIEAVRLLRKTFPSLLVACDVCLCPYTSHGHCGLL 135 Query: 279 SDGAAAILLARRSKAEELGLPILGVLRSYAVVGVP---PDIMGIGPAYAIPVALQKAGL 334 S+ A + R + E+ L +YA G P M G AI AL K GL Sbjct: 136 SENGAFLSEESRQRLAEVAL-------AYAKAGCQVVAPSDMMDGRVEAIKAALLKHGL 187 >5XTD-T nrPDB Length = 95 Score = 29.9 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%) Query: 343 EINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHP 378 E+NE FA + + GG ALGHP Sbjct: 34 EVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHP 69 >2IVO-A nrPDB Length = 330 Score = 29.5 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 16/27 (59%), Gaps = 4/27 (14%) Query: 323 YAIPVALQKAGLTVSDVDIFEINEAFA 349 + AL +AG+++ D+D+ AF+ Sbjct: 53 PLLRKALSEAGVSLDDIDVI----AFS 75 >5O31-R nrPDB Length = 96 Score = 29.5 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 17/36 (47%) Query: 343 EINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHP 378 E+NE FA ++ ++ GG ALGHP Sbjct: 34 EVNENFAIDLIAEQPVSQVGSRVISCDGGGGALGHP 69 >5GUP-F nrPDB Length = 123 Score = 29.2 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 16/36 (44%) Query: 343 EINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHP 378 E+NE FA + ++ GG ALGHP Sbjct: 61 EVNENFAIDLIAEQPVSEVGSRVISCDGGGGALGHP 96 >5LNM-A nrPDB Length = 206 Score = 29.2 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 7/32 (21%), Positives = 12/32 (37%), Gaps = 1/32 (3%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVHGRRTAIC 49 G +P+ + S ++ V V R I Sbjct: 12 GLVPRGSHMASTDSESETR-VKSVRTGRKPIG 42 >4IEI-A nrPDB Length = 490 Score = 29.2 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 16/53 (30%), Gaps = 4/53 (7%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMT 70 G +P + S P + R + + GRG K LL Sbjct: 13 GLVPAGSHMTSINPIFEP----FIEAHRYKVAKGGRGSGKSWAIARLLVEAAR 61 >3U0E-A nrPDB Length = 428 Score = 28.8 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 33/113 (29%), Gaps = 28/113 (24%) Query: 67 AVMTAVLKDVNLRPEQLGDICVGNVLQPGA--------GAIMARIAQFLSDIPETVPL-- 116 M + D L E++ + G ++ G A + R P VP Sbjct: 98 IAMDQAIADAGLTEEEVSNERTGIIMGSGGPSTRTIVDSADITREKGPKRVGPFAVPKAM 157 Query: 117 ------------------STVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 151 +++ C++ + + I+ G D A G E Sbjct: 158 SSTASATLATFFKIKGINYSISSACATSNHCIGNAYEMIQYGKQDRMFAGGCE 210 >6IOX-A nrPDB Length = 340 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 5/72 (6%) Query: 266 KDGSTTAGNSS----QVSDGAAAILLARRSKAEELG-LPILGVLRSYAVVGVPPDIMGIG 320 KDG + + +D A I +A A+ + + + S++ G M Sbjct: 169 KDGLLLVADCAVIPNPTADELAQIAVATARTAKAIADIEPRVAMLSFSTKGSAKHEMTDK 228 Query: 321 PAYAIPVALQKA 332 A +A + A Sbjct: 229 VVEATRMAQEMA 240 >4TLZ-A nrPDB Length = 443 Score = 28.4 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 14/25 (56%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVH 42 G +P+ + ++ A ++ DVV V Sbjct: 13 GLVPRGSHMVAHAGESPTHDVVGVG 37 >4ANI-C nrPDB Length = 509 Score = 28.4 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 11/23 (47%), Positives = 14/23 (60%), Gaps = 3/23 (13%) Query: 318 GIGPAYAIPVALQKAGLTVSDVD 340 +GP ALQ AGLT +D+D Sbjct: 285 TMGPV---RQALQDAGLTPADID 304 >5ODO-A nrPDB Length = 578 Score = 28.4 bits (62), Expect = 6.5, Method: Composition-based stats. Identities = 6/28 (21%), Positives = 12/28 (42%) Query: 17 SGWMPQAAPCLSGAPQASAADVVVVHGR 44 SG +P+ + S + S ++ G Sbjct: 8 SGLVPRGSHMASMSSNLSHKAYMIGAGI 35 >2D0P-A nrPDB Length = 610 Score = 28.4 bits (62), Expect = 6.5, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 8/75 (10%) Query: 273 GNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKA 332 GNSS + LA +A L + + + + G ++ GI A A + + A Sbjct: 10 GNSST------EVALATLDEAGALTITHSALAETTGIKGTLRNVFGIQEALA--LVARGA 61 Query: 333 GLTVSDVDIFEINEA 347 G+ VSD+ + INEA Sbjct: 62 GIAVSDISLIRINEA 76 >3P1L-A nrPDB Length = 393 Score = 28.4 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 20/74 (27%), Gaps = 10/74 (13%) Query: 18 GWMPQAAPC---------LSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAV 68 G +P+ + + +P + + + +G G F L V Sbjct: 13 GLVPRGSHMSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNV 72 Query: 69 MTAVLKDVNLRPEQ 82 + A L Sbjct: 73 VYAA-DRAGLVKAL 85 >4RQ9-A nrPDB Length = 348 Score = 28.4 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 6/31 (19%), Positives = 15/31 (48%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVHGRRTAI 48 G +P+ + + A ++ +V + + R I Sbjct: 13 GLVPRGSHMSTEASRSGKQEVDLTNCDREPI 43 >1W2A-X nrPDB Length = 331 Score = 28.4 bits (62), Expect = 6.8, Method: Composition-based stats. Identities = 5/20 (25%), Positives = 10/20 (50%) Query: 18 GWMPQAAPCLSGAPQASAAD 37 G +P+ + + P S A+ Sbjct: 13 GLVPRGSHMDTTVPTFSLAE 32 >1DXL-A nrPDB Length = 470 Score = 28.4 bits (62), Expect = 7.0, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 24/69 (34%), Gaps = 2/69 (2%) Query: 25 PCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRP-EQL 83 P G ADVV+V RT D+L ++ N+ + Sbjct: 257 PSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVETDKLGRILVNERFS-TNVSGVYAI 315 Query: 84 GDICVGNVL 92 GD+ G +L Sbjct: 316 GDVIPGPML 324 >6ET3-B nrPDB Length = 283 Score = 28.0 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 19/57 (33%), Gaps = 12/57 (21%) Query: 323 YAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPL 379 A+ AL +A + ++D+ + + A +GHPL Sbjct: 40 PAVREALDEAAVKPEEIDLI--------VGLALSPDHLIENRDIM----APKIGHPL 84 >5LVW-A nrPDB Length = 413 Score = 28.0 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 39/104 (37%), Gaps = 26/104 (25%) Query: 289 RRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIP-VALQKA---GLTVSD------ 338 R A +LGLP L + A + V + +G A + ++KA G+ S Sbjct: 235 SRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTD 294 Query: 339 --------------VDIFEINEAFASQAA--YCVEKLRLPPEKV 366 +D E++ A A+ A + + LP ++ Sbjct: 295 SRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSEL 338 >4OXP-A nrPDB Length = 290 Score = 28.0 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 14/33 (42%), Gaps = 4/33 (12%) Query: 18 GWMPQAAP----CLSGAPQASAADVVVVHGRRT 46 G +P+ + L A A VVVV G R Sbjct: 13 GLVPRGSHMSKKMLIDAAHAEETRVVVVDGTRV 45 >3T5Y-A nrPDB Length = 357 Score = 28.0 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 17/124 (13%), Positives = 40/124 (32%), Gaps = 8/124 (6%) Query: 73 LKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVAS 132 L ++ P + + ++ G A + VP + ++C+ G+ A+ Sbjct: 66 LGRGDVDPADVSLVLHSSLWFQGIDLWPAASYVAHEAVGRHVPAFGLAQRCNGGMGAIEL 125 Query: 133 IAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERF 192 + +G + G ++ G R + G + ++ R Sbjct: 126 AGAYLGSG-----IGAGHAALLTTGDRFAGPRIDR---WNSVDVTMYGDGAAALVLSTRD 177 Query: 193 GISR 196 G +R Sbjct: 178 GFAR 181 >4OH7-A nrPDB Length = 320 Score = 28.0 bits (61), Expect = 8.7, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 13/37 (35%) Query: 56 FKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVL 92 EL + + A + L+ ++ G VL Sbjct: 21 LSTVPATELRAILEDAKARKARLKAGEVERPYAGKVL 57 >3OA3-A nrPDB Length = 288 Score = 28.0 bits (61), Expect = 9.2, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 42/110 (38%), Gaps = 19/110 (17%) Query: 56 FKDTTPDELLS--AVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARI---------- 103 F+D L + A++ +L+ L +I G VL AGA + Sbjct: 161 FQDIRAVRLAAKDAILKVILETSQLTA---DEIIAGCVLSSLAGADYVKTSTGFNGPGAS 217 Query: 104 ---AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGV 150 +S + +++ T + G++ + +R G+ +G + GV Sbjct: 218 IENVSLMSAVCDSLQSETRVKASG-GIRTIEDCVKMVRAGAERLGASAGV 266 >5TNV-A nrPDB Length = 326 Score = 27.6 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 16/48 (33%), Gaps = 1/48 (2%) Query: 18 GWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELL 65 G +P+ + S AA++ + G R + +L Sbjct: 13 GLVPRGSHMYSAHTWPIAANM-LGFGNRAPDGGHIKDAPAGVWAKQLR 59 >3VEW-A nrPDB Length = 576 Score = 27.6 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 12/24 (50%) Query: 319 IGPAYAIPVALQKAGLTVSDVDIF 342 P A L +AGLTV D+D Sbjct: 50 TAPVQAAAFCLAQAGLTVDDLDAV 73 >2X3E-A nrPDB Length = 331 Score = 27.6 bits (60), Expect = 10.0, Method: Composition-based stats. Identities = 30/139 (21%), Positives = 45/139 (32%), Gaps = 33/139 (23%) Query: 280 DGAAAILLARRSKAEELGL----------------PILGVLRSYAVVGVPPDIMGIGP-- 321 DGA A++L EE L V R+ G + + Sbjct: 159 DGAGAVVLRAGDAEEEGALLAFDLGSDGHQFDLLMTP-AVSRAERSSGQASNYFRMDGKA 217 Query: 322 ---------AYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPL--- 369 + ++ L + G SD+ ++A A ++L LP E+V Sbjct: 218 VFGQAVTQMSDSVRRVLDRVGWQASDLHHLVPHQANTRILAAVADQLDLPVERVVSNIAE 277 Query: 370 -GGAVALGHPLG-CTGARQ 386 G VA PL G RQ Sbjct: 278 VGNTVAASIPLALAHGLRQ 296 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.144 0.402 Lambda K H 0.267 0.0440 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,699,069 Number of Sequences: 36641 Number of extensions: 701740 Number of successful extensions: 3775 Number of sequences better than 10.0: 157 Number of HSP's better than 10.0 without gapping: 137 Number of HSP's successfully gapped in prelim test: 72 Number of HSP's that attempted gapping in prelim test: 3228 Number of HSP's gapped (non-prelim): 307 length of query: 424 length of database: 10,336,785 effective HSP length: 100 effective length of query: 324 effective length of database: 6,672,685 effective search space: 2161949940 effective search space used: 2161949940 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)