BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P09104 (434 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3UJR-A nrPDB 890 0.0 3B97-A nrPDB 764 0.0 2XSX-A nrPDB 761 0.0 1PDZ-A nrPDB 657 0.0 5WRO-A nrPDB 634 0.0 3QTP-A nrPDB 568 e-162 3OTR-A nrPDB 560 e-160 2XH7-A nrPDB 556 e-159 2PU1-A nrPDB 531 e-151 4G7F-A nrPDB 531 e-151 2PA6-A nrPDB 455 e-128 4Z1Y-A nrPDB 448 e-126 4A3R-A nrPDB 436 e-123 4MKS-A nrPDB 436 e-122 1IYX-A nrPDB 432 e-121 5J04-A nrPDB 419 e-118 5BOE-A nrPDB 417 e-117 6BFZ-A nrPDB 416 e-117 6NB2-A nrPDB 412 e-115 3UJ2-A nrPDB 412 e-115 3ZLH-A nrPDB 406 e-114 1W6T-A nrPDB 403 e-112 6O4N-A nrPDB 389 e-108 3TQP-A nrPDB 386 e-108 6J36-A nrPDB 365 e-101 3QN3-A nrPDB 363 e-100 3R11-A nrPDB 44 1e-04 3IK4-A nrPDB 43 3e-04 4MMW-A nrPDB 39 0.006 1WUE-A nrPDB 37 0.018 4MGG-A nrPDB 36 0.030 3S5S-A nrPDB 33 0.21 3UXL-A nrPDB 33 0.25 5X3E-A nrPDB 32 0.70 2Z8X-A nrPDB 31 0.91 3QLD-A nrPDB 31 0.92 4JMP-A nrPDB 31 1.2 3JW7-A nrPDB 30 1.4 1TKK-A nrPDB 30 1.5 2PGE-A nrPDB 30 2.1 2YCB-A nrPDB 28 5.6 5DMB-A nrPDB 28 6.1 2E2P-A nrPDB 28 6.5 5HQA-A nrPDB 28 7.2 5AOU-A nrPDB 28 7.7 3MV5-A nrPDB 28 8.7 >3UJR-A nrPDB Length = 443 Score = 890 bits (2300), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/433 (100%), Positives = 433/433 (100%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG Sbjct: 1 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 60 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA Sbjct: 121 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 180 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 241 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV Sbjct: 181 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 240 Query: 242 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 300 Query: 302 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 361 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ Sbjct: 301 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 360 Query: 362 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 421 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA Sbjct: 361 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 420 Query: 422 RFAGHNFRNPSVL 434 RFAGHNFRNPSVL Sbjct: 421 RFAGHNFRNPSVL 433 >3B97-A nrPDB Length = 433 Score = 764 bits (1972), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/430 (83%), Positives = 395/430 (91%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 SI KI AREI DSRGNPTVEVDL+T+KGLFRAAVPSGASTGIYEALELRD DK RY+GKG Sbjct: 1 SILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKG 60 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV+HIN TIAPAL+S L+V EQEK+D LM+E+DGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 GA E+ +PLYRHIA LAGNS++ILPVPAFNVINGGSHAGNKLAMQEFMILPVGA +FR+A Sbjct: 121 GAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREA 180 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 241 MR+GAEVYH LK VIK+KYGKDATNVGDEGGFAPNILEN E LEL+K AI KAGYT+K+V Sbjct: 181 MRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVV 240 Query: 242 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 IGMDVAASEF+R GKYDLDFKSP DPSRYI+ DQL LY+ F++DYPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDW 300 Query: 302 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 361 AW KFTA+ GIQ+VGDDLTVTNPKRI +AV EK+CNCLLLKVNQIGSVTE++QACKLAQ Sbjct: 301 GAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQ 360 Query: 362 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 421 NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQL+RIEEELG +A Sbjct: 361 ANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKA 420 Query: 422 RFAGHNFRNP 431 +FAG NFRNP Sbjct: 421 KFAGRNFRNP 430 >2XSX-A nrPDB Length = 435 Score = 761 bits (1964), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/431 (83%), Positives = 398/431 (92%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 M+++KI+AREILDSRGNPTVEVDL+TAKG FRAAVPSGASTGIYEALELRDGDK RYLGK Sbjct: 2 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 61 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 GVLKAV++INST+ PAL+ LSV +QEK+D M+ELDGTENKSKFGANAILGVSLAVCK Sbjct: 62 GVLKAVENINSTLGPALLQKKLSVADQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 121 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 AGAAE+ +PLYRHIA LAGN DLILPVPAFNVINGGSHAGNKLAMQEFMILPVGA SF++ Sbjct: 122 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 181 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 AMR+GAEVYH LKGVIK KYGKDATNVGDEGGFAPNILEN+EALEL+K AI AGY +K+ Sbjct: 182 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 241 Query: 241 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 300 VIGMDVAASEFYR+GKYDLDFKSP DP+R+ITG++LG LY+ F+++YPVVSIEDPFDQDD Sbjct: 242 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 301 Query: 301 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA 360 WA W+ F + V IQIVGDDLTVTNPKRI +AVE+KACNCLLLKVNQIGSVTE+IQACKLA Sbjct: 302 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 361 Query: 361 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE 420 Q NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE LGD+ Sbjct: 362 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 421 Query: 421 ARFAGHNFRNP 431 A FAG FRNP Sbjct: 422 AIFAGRKFRNP 432 >1PDZ-A nrPDB Length = 434 Score = 657 bits (1695), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/433 (73%), Positives = 360/433 (83%), Gaps = 2/433 (0%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 SI K++AR I DSRGNPTVEVDLYT+KGLFRAAVPSGASTG++EALE+RDGDK +Y GK Sbjct: 2 SITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKS 61 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V AV ++N I P +I SGL V +Q++ D M +LDGTENKS GANAILGVSLA+CKA Sbjct: 62 VFNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 GAAE +PLYRHIA LA ++ILPVPAFNVINGGSHAGNKLAMQEFMILP GA SF +A Sbjct: 122 GAAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEA 181 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 241 MR+G EVYH LK VIK ++G DAT VGDEGGFAPNIL N +AL+L++EAI KAGYT KI Sbjct: 182 MRMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTGKIE 241 Query: 242 IGMDVAASEFYRDGK-YDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 IGMDVAASEFY+ YDLDFK+ D S+ I+GDQL +Y +F +D+P+VSIEDPFDQD Sbjct: 242 IGMDVAASEFYKQNNIYDLDFKTANNDGSQKISGDQLRDMYMEFCKDFPIVSIEDPFDQD 301 Query: 300 DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 DW WSK T+ IQIVGDDLTVTNPKRI AVE+KAC CLLLKVNQIGSVTE+I A L Sbjct: 302 DWETWSKMTSGTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVTESIDAHLL 361 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGD 419 A++NGWG MVSHRSGETED FIADLVVGLCTGQIKTGAPCRSERLAKYNQ++RIEEELG Sbjct: 362 AKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGS 421 Query: 420 EARFAGHNFRNPS 432 A+FAG NFR PS Sbjct: 422 GAKFAGKNFRAPS 434 >5WRO-A nrPDB Length = 439 Score = 634 bits (1636), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/432 (72%), Positives = 362/432 (83%), Gaps = 1/432 (0%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 +I+ I AR+I DSRGNPTVEVDL T GLFRAAVPSGASTG++EALELRD DK Y GK Sbjct: 7 FTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGK 66 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 VLKAV H+N T+ P LI + L VV+Q +DN M++LDGTENKSKFGANAILGVSLAV K Sbjct: 67 SVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAK 126 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 AGAA++ +PLY+HIA LAGN ++ILPVPAFNVINGGSHAGNKLAMQEFMILP GA SF + Sbjct: 127 AGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTE 186 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 AM++G+EVYH LK VIK K+G DAT VGDEGGFAPNI N EAL L+ +AI KAGYT KI Sbjct: 187 AMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKI 246 Query: 241 VIGMDVAASEFYRDGKYDLDFKS-PTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 IGMDVAASEFY+DG+YDLDFK+ +D S+++ D+L LYQ+F++D+P+VSIEDPFDQD Sbjct: 247 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQD 306 Query: 300 DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 W AWS T IQIVGDDLTVTNPKRI AVE+KACNCLLLKVNQIG+VTE+I A L Sbjct: 307 HWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLL 366 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGD 419 A++NGWG MVSHRSGETED+FI DLVVGL TGQIKTGAPCRSERLAKYNQ++RIEEE+G Sbjct: 367 AKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGA 426 Query: 420 EARFAGHNFRNP 431 +FAG +FR P Sbjct: 427 GVKFAGKSFRKP 438 >3QTP-A nrPDB Length = 441 Score = 568 bits (1465), Expect = e-162, Method: Compositional matrix adjust. Identities = 280/438 (63%), Positives = 345/438 (78%), Gaps = 9/438 (2%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 MSI+K+ AREILDSRGNPT+EV++ T KG+FR+ VPSGASTG++EA+ELRDGDK+RY GK Sbjct: 6 MSIQKVHAREILDSRGNPTIEVEITTGKGMFRSCVPSGASTGVHEAVELRDGDKKRYGGK 65 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 GVLKAV+++N+ I PAL+ G +V+ Q +LD +M++LDGT NK K GANAILG S+++C+ Sbjct: 66 GVLKAVENVNTIIGPALL--GKNVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICR 123 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A AAE+ LPLY+++A+L G+ ++ +PVP FNVINGG+HAGN LAMQEFMI P GA +F + Sbjct: 124 AAAAEKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHE 183 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 A+R+ AE Y LK VIK KYG+DATNVGDEGGFAPN+ EAL+L+ EAI KAGYT KI Sbjct: 184 ALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGYTGKI 243 Query: 241 VIGMDVAASEFYRD--GKYDLDFKSPT---DPSRYITGDQLGALYQDFVRDYPVVSIEDP 295 I MD AASEFY + KYDL K P DPS D L A Y D+ + YP+ SIEDP Sbjct: 244 EIAMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKHYPIASIEDP 303 Query: 296 FDQDDWAAWSKFTANVG-IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAI 354 F +DDWAAW+KFT G QIVGDDL VTNP R++ A+++ ACN +L+KVNQIG++TE Sbjct: 304 FAEDDWAAWNKFTVEHGNFQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETF 363 Query: 355 QACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 + K+AQE GWGVM SHRSGETEDTFIADLVVGL QIKTGAPCRSERL KYNQLMRIE Sbjct: 364 KTIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIE 423 Query: 415 EELGDEARFAGHNFRNPS 432 EELG+ +AG N+RN + Sbjct: 424 EELGN-IPYAGKNWRNST 440 >3OTR-A nrPDB Length = 452 Score = 560 bits (1444), Expect = e-160, Method: Compositional matrix adjust. Identities = 283/442 (64%), Positives = 352/442 (79%), Gaps = 15/442 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 I+ I AREILDSRGNPT+EVD+ T G+FRAAVPSGASTGIYEALELRD D +RYLGKGV Sbjct: 4 IKDIVAREILDSRGNPTIEVDVSTEGGVFRAAVPSGASTGIYEALELRDKDPKRYLGKGV 63 Query: 63 LKAVDHINSTIAPALISSGLSVVEQEKLDNLMLE-LDGTEN-----KSKFGANAILGVSL 116 L AV+ + I PAL+ G +Q+ +D LM+E LDGT+N KSK GANAILGVS+ Sbjct: 64 LNAVEIVRQEIKPALL--GKDPCDQKGIDMLMVEQLDGTKNEWGYSKSKLGANAILGVSI 121 Query: 117 AVCKAGAAERELPLYRHIAQLAGNS--DLILPVPAFNVINGGSHAGNKLAMQEFMILPVG 174 A C+AGAA + LPLY++IA LAG + +++PVP FNVINGG HAGN LA+QEF+I PVG Sbjct: 122 ACCRAGAASKGLPLYKYIATLAGKTIDKMVMPVPFFNVINGGEHAGNGLALQEFLIAPVG 181 Query: 175 AESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKA 234 A + R+A+R G+E YH LK VIK+KYG DATNVGDEGGFAPN+ EAL L+ EAI A Sbjct: 182 APNIREAIRYGSETYHHLKNVIKNKYGLDATNVGDEGGFAPNVATAEEALNLLVEAIKAA 241 Query: 235 GYTEKIVIGMDVAASEFYR--DGKYDLDFKSPT-DPSRYITGDQLGALYQDFVRDYPVVS 291 GY KI I D AASEFY+ + KYDLD+K T + S+++TG++L +Y+ +++ YP++S Sbjct: 242 GYEGKIKIAFDAAASEFYKQDEKKYDLDYKCKTKNASKHLTGEKLKEVYEGWLKKYPIIS 301 Query: 292 IEDPFDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGS 349 +EDPFDQDD+A++S FT +VG Q++GDD+ VTN RIE+A+++KACNCLLLKVNQIGS Sbjct: 302 VEDPFDQDDFASFSAFTKDVGEKTQVIGDDILVTNILRIEKALKDKACNCLLLKVNQIGS 361 Query: 350 VTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQ 409 VTEAI+AC LAQ++GWGV VSHRSGETED+FIADLVVGL GQIK+G+PCRSERL KYNQ Sbjct: 362 VTEAIEACLLAQKSGWGVQVSHRSGETEDSFIADLVVGLRCGQIKSGSPCRSERLCKYNQ 421 Query: 410 LMRIEEELGDEARFAGHNFRNP 431 LMRIEE LG + +AG +FR+P Sbjct: 422 LMRIEESLGADCVYAGESFRHP 443 >2XH7-A nrPDB Length = 443 Score = 556 bits (1432), Expect = e-159, Method: Compositional matrix adjust. Identities = 269/430 (62%), Positives = 340/430 (79%), Gaps = 3/430 (0%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 ++ K++AR + DSRGNPTVEV+L T KG+FR+ VPSGASTG++EALE+RDGDK +++GKG Sbjct: 1 AVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKG 60 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VL AV ++N IAPA + + + V +Q+ +D+ ++ LDGT NKSK GANAILGVSLA +A Sbjct: 61 VLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRA 120 Query: 122 GAAERELPLYRHIAQLAGN--SDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 AAE+ +PLY+H+A L+ + S +LPVP NV+NGGSHAG LA+QEFMI P GA++F Sbjct: 121 AAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFA 180 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEK 239 +A+R+G+EVYH LK + K +YG A NVGDEGG APNI EAL+L+ +AI AG+ K Sbjct: 181 EALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGK 240 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I IG+D A+SEF++DGKYDLDFK+P +D S+++TG QL LY ++ YP+VSIEDPF + Sbjct: 241 IKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAE 300 Query: 299 DDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 DDW AWS F GIQIV D LTVTNPKRI A+E+KA + LLLKVNQIG+++E+I+A + Sbjct: 301 DDWEAWSHFFKTAGIQIVADALTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360 Query: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418 + GWGVMVSHRSGETEDTFIADLVVGL TGQIKTGAP RSERLAK NQL+RIEEELG Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420 Query: 419 DEARFAGHNF 428 D A FAG NF Sbjct: 421 DNAVFAGENF 430 >2PU1-A nrPDB Length = 432 Score = 531 bits (1368), Expect = e-151, Method: Compositional matrix adjust. Identities = 269/427 (62%), Positives = 335/427 (78%), Gaps = 8/427 (1%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 M+I+K+ RE+LDSRGNPTVEV++ T KG+FR+AVPSGASTG+YEA ELRDGDK+RY+GK Sbjct: 4 MTIQKVHGREVLDSRGNPTVEVEVTTEKGVFRSAVPSGASTGVYEACELRDGDKKRYVGK 63 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 G L+AV ++N I PALI G ++QE+LD LML LDGT NK K GANAILG S+A+ K Sbjct: 64 GCLQAVKNVNEVIGPALI--GRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISK 121 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A AA + +PLYR++A LAG +L LPVP FNVINGG HAGN L QEFMI PV A SF + Sbjct: 122 AAAAAKGVPLYRYLASLAGTKELRLPVPCFNVINGGKHAGNALPFQEFMIAPVKATSFSE 181 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 A+R+G+EVYH+L+G+IK KYG+DA NVGDEGGFAP I + +E L ++ EAI++AG+ K Sbjct: 182 ALRMGSEVYHSLRGIIKKKYGQDAVNVGDEGGFAPPIKDINEPLPILMEAIEEAGHRGKF 241 Query: 241 VIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I MD AASE Y + K Y+L FKSP +P+ ++T +QL Y + DYP+VSIEDP+DQ Sbjct: 242 AICMDCAASETYDEKKQQYNLTFKSP-EPT-WVTAEQLRETYCKWAHDYPIVSIEDPYDQ 299 Query: 299 DDWAAWSKFTANV--GIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 DD+A ++ T + QIVGDDLTVTN +RI+ A+E+KACN LLLK+NQIG+++EAI + Sbjct: 300 DDFAGFAGITEALKGKTQIVGDDLTVTNTERIKMAIEKKACNSLLLKINQIGTISEAIAS 359 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 KL ENGW VMVSHRSGETEDT+IADLVV L +GQIKTGAPCR ER AK NQL+RIEEE Sbjct: 360 SKLCMENGWSVMVSHRSGETEDTYIADLVVALGSGQIKTGAPCRGERTAKLNQLLRIEEE 419 Query: 417 LGDEARF 423 LG A+F Sbjct: 420 LGAHAKF 426 >4G7F-A nrPDB Length = 429 Score = 531 bits (1368), Expect = e-151, Method: Compositional matrix adjust. Identities = 264/427 (61%), Positives = 328/427 (76%), Gaps = 8/427 (1%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 M+I+K+ REILDSRGNPTVEV++ T G+FR+AVPSGASTGI+EA ELRD DK+RYLGK Sbjct: 1 MTIQKVHGREILDSRGNPTVEVEVTTELGVFRSAVPSGASTGIHEACELRDDDKRRYLGK 60 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 G L AV ++N +APAL+ G ++Q LD LM +LDGT NKSK GANAILG S+A+ K Sbjct: 61 GCLNAVKNVNDVLAPALV--GKDELQQSTLDKLMRDLDGTPNKSKLGANAILGCSMAISK 118 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A AA + +PLYR++A+LAG ++ LPVP FNVINGG HAGN L QEFMI PV A SF + Sbjct: 119 AAAARKGVPLYRYLAELAGTKEVRLPVPCFNVINGGKHAGNALPFQEFMIAPVKAGSFNE 178 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 A+R+GAEVYH+LK +IK KYG+DA NVGDEGGFAP I + +E L ++ EAI++AG+ + Sbjct: 179 ALRMGAEVYHSLKSIIKKKYGQDAVNVGDEGGFAPPITDINEPLPILMEAIEQAGHKGRF 238 Query: 241 VIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I MD AASE Y + K Y+L FKSP + ++T QL Y +V +YP+VS+EDP+DQ Sbjct: 239 AICMDSAASETYDENKKQYNLTFKSPE--ATWVTAKQLAETYAKWVSEYPIVSLEDPYDQ 296 Query: 299 DDWAAWSKFTANV--GIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 DD+ ++ T + Q+VGDDLTVTN RI+ A+E+KACN LLLK+NQIG++TEAI+A Sbjct: 297 DDFDGFAGITEALKGKAQVVGDDLTVTNVSRIKTAIEKKACNSLLLKINQIGTITEAIEA 356 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 K NGW VMVSHRSGETEDT+IADLVVGL TGQIKTGAPCR ER AK NQL+RIEEE Sbjct: 357 SKFCMSNGWSVMVSHRSGETEDTYIADLVVGLGTGQIKTGAPCRGERTAKLNQLLRIEEE 416 Query: 417 LGDEARF 423 LG A+F Sbjct: 417 LGAHAKF 423 >2PA6-A nrPDB Length = 427 Score = 455 bits (1170), Expect = e-128, Method: Compositional matrix adjust. Identities = 244/432 (56%), Positives = 319/432 (73%), Gaps = 15/432 (3%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYT-AKGLFRAAVPSGASTGIYEALELRDGDKQRYLG 59 I+ I ARE++DSRGNPTVEV++ T G A VPSGASTG +EALELRD +K R+ G Sbjct: 9 FEIKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEK-RFGG 67 Query: 60 KGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVC 119 KGVL AV+++NS I P ++ G Q ++D +M+ELDGT NKS+ GANAIL VSLAV Sbjct: 68 KGVLMAVENVNSIIRPEIL--GYDARMQREIDTIMIELDGTPNKSRLGANAILAVSLAVA 125 Query: 120 KAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 KA AA ++PLY++ L G + ++PVP NVINGG HAGN L +QEFMI+PVGA S Sbjct: 126 KAAAATAKIPLYKY---LGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMPVGATSIS 182 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEK 239 +A+R+G+EVYH LK VI +KYGK+A NVGDEGGFAP + + EAL+L+ E++ KAGY ++ Sbjct: 183 EAVRMGSEVYHVLKNVILEKYGKNAVNVGDEGGFAPPLKTSREALDLLTESVKKAGYEDE 242 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 +V +D AASEFY+DG Y ++ K +T ++L Y+ V +YP+VSIEDPF ++ Sbjct: 243 VVFALDAAASEFYKDGYYYVEGKK-------LTREELLDYYKALVDEYPIVSIEDPFHEE 295 Query: 300 DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 D+ ++ T + IQIVGDDL VTN +R+ + +E KA N LLLKVNQIG+++EA+ A +L Sbjct: 296 DFEGFAMITKELDIQIVGDDLFVTNVERLRKGIEMKAANALLLKVNQIGTLSEAVDAAQL 355 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGD 419 A NG+GV+VSHRSGETEDT IADL V L +GQIKTGAP R ER AKYNQL+RIE+ELG Sbjct: 356 AFRNGYGVVVSHRSGETEDTTIADLSVALNSGQIKTGAPARGERTAKYNQLIRIEQELG- 414 Query: 420 EARFAGHNFRNP 431 +++AG NFR P Sbjct: 415 LSKYAGRNFRCP 426 >4Z1Y-A nrPDB Length = 426 Score = 448 bits (1153), Expect = e-126, Method: Compositional matrix adjust. Identities = 241/430 (56%), Positives = 302/430 (70%), Gaps = 17/430 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKG-LFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 IE I ARE+LDSRGNPT+EVD+ G + RA VPSGASTG +EALELRDGDK RY GKG Sbjct: 5 IEAIVAREVLDSRGNPTIEVDVRLESGDVGRAIVPSGASTGAHEALELRDGDKSRYNGKG 64 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VLKAV +N IA ALI G +Q LD ++ LDGT NKSK GANAILGVSLA KA Sbjct: 65 VLKAVQAVNEDIAEALI--GFDAADQIALDQELIALDGTPNKSKLGANAILGVSLAAAKA 122 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 AA LPLYR+ L G +LPVP N++NGG HA N QEFMI+PVGAESFR+ Sbjct: 123 AAAAFGLPLYRY---LGGVYAHVLPVPMMNIMNGGQHATNSTDFQEFMIMPVGAESFREG 179 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R GAE+YH LK VI D+ +T VGDEGGFAP++ N L+L+ EAI+KAGY E+ Sbjct: 180 LRWGAEIYHMLKKVIHDR--GFSTTVGDEGGFAPSLPTNDAPLQLIMEAIEKAGYRPGEQ 237 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 IVI +D A +E + DGKY L + R ++ ++ + D V YP++S+ED +D Sbjct: 238 IVIALDPATTEIFEDGKYHLKREG-----RSLSSAEMVDYWVDLVNRYPIISLEDGLAED 292 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 DW W+ A +G +Q+VGDD VTN +R++RA+E KA N +L+K+NQIGS+TE + A Sbjct: 293 DWEGWALLRAKLGDRVQLVGDDFLVTNVQRLQRAIEAKAANSILIKLNQIGSLTETLSAI 352 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 +LAQ +GW +VSHRSGE+ED IADLVV GQIKTGAP R++R+AKYNQL+RIEEEL Sbjct: 353 QLAQRSGWTAVVSHRSGESEDVTIADLVVATNAGQIKTGAPARTDRIAKYNQLLRIEEEL 412 Query: 418 GDEARFAGHN 427 G AR+AG + Sbjct: 413 GSAARYAGRS 422 >4A3R-A nrPDB Length = 430 Score = 436 bits (1122), Expect = e-123, Method: Compositional matrix adjust. Identities = 225/432 (52%), Positives = 306/432 (70%), Gaps = 19/432 (4%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPTVEV++YT G F RA VPSGASTG YEA+ELRDGDK RYLGKG Sbjct: 4 IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKG 63 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VL AV+++N IAP L+ G V EQ +D L++ELDGTENK K GANAILGVS+A +A Sbjct: 64 VLTAVNNVNEIIAPELL--GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A ++PLY++ L G + LPVP N++NGG HA N + +QEFMI+PVGA +FR+A Sbjct: 122 AADFLQIPLYQY---LGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREA 178 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R+GA+++H+LK V+ K G + T VGDEGGFAPN+ N EAL+ + EAI+KAG+ E+ Sbjct: 179 LRMGAQIFHSLKSVLSAK-GLN-TAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEE 236 Query: 240 IVIGMDVAASEFY--RDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFD 297 + + MD A+SEFY DGKY L + S ++ Y++ V YP++SIED D Sbjct: 237 VKLAMDAASSEFYNKEDGKYHLSGEGVVKTSA-----EMVDWYEELVSKYPIISIEDGLD 291 Query: 298 QDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQ 355 ++DW T +G +Q+VGDDL VTN K++ ++ N +L+KVNQIG++TE Sbjct: 292 ENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFD 351 Query: 356 ACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+ G+ ++SHRSGETED+ IAD+ V GQIKTGAP R++R+AKYNQL+RIE+ Sbjct: 352 AIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIED 411 Query: 416 ELGDEARFAGHN 427 +L + A++ G N Sbjct: 412 QLAETAQYHGIN 423 >4MKS-A nrPDB Length = 440 Score = 436 bits (1121), Expect = e-122, Method: Compositional matrix adjust. Identities = 230/435 (52%), Positives = 305/435 (70%), Gaps = 18/435 (4%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I I ARE+LDSRGNPT E ++YT G F RA VPSGASTG +EA+ELRDGDK R+ G+G Sbjct: 4 ITDIHAREVLDSRGNPTAEAEVYTELGGFGRAIVPSGASTGEHEAVELRDGDKSRFGGQG 63 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VL AV+++N IA A+I GL V +Q +D M++LDGT NK + GANAIL VSLA +A Sbjct: 64 VLTAVENVNGEIAKAVI--GLDVTDQRLIDQTMIDLDGTPNKGRLGANAILSVSLASARA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A E LPLY + L G + +LP P NVINGG HA N + +QEFMI+PVGA+S +A Sbjct: 122 AADELGLPLYEY---LGGPNAHVLPTPMMNVINGGKHADNNVDIQEFMIMPVGAKSLHEA 178 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R+GAE +HTLKG+++++ ++T VGDEGGFAPN+ N E E++ EAI +AGY + Sbjct: 179 VRMGAETFHTLKGLLQER--GESTAVGDEGGFAPNLKNNEEPFEILVEAIQRAGYKPGQD 236 Query: 240 IVIGMDVAASEFY-RDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I I D AASEFY +D K + + D Y T ++ +L +D V YPV+S+EDP D+ Sbjct: 237 IAIAFDCAASEFYNKDTK---KYVTVADGREY-TAEEWTSLIEDLVDKYPVISVEDPLDE 292 Query: 299 DDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 +DW W FT +G +QIVGDDL VTN +E+ ++ N +L+K+NQIG++TE +A Sbjct: 293 NDWEGWKTFTERLGDKVQIVGDDLFVTNTSYLEKGIKMGVANSILIKLNQIGTLTETFEA 352 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 ++A+E G+ +VSHRSGETEDT IADLVV GQIKTG+ R++R+AKYNQLMRIEE Sbjct: 353 IEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEEA 412 Query: 417 LGDEARFAG-HNFRN 430 LG A++ G H+F N Sbjct: 413 LGSTAQYKGIHSFYN 427 >1IYX-A nrPDB Length = 432 Score = 432 bits (1110), Expect = e-121, Method: Compositional matrix adjust. Identities = 224/436 (51%), Positives = 305/436 (69%), Gaps = 19/436 (4%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++AREILDSRGNPT+EV++YT G F R VPSGASTG YEA+ELRDGDK RY GKG Sbjct: 4 ITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYGGKG 63 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAVD++N+ IA A+I G V +Q +D M+ LDGT NK K GANAILGVS+AV +A Sbjct: 64 VTKAVDNVNNIIAEAII--GYDVRDQMAIDKAMIALDGTPNKGKLGANAILGVSIAVARA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A E+PLY + L G + +LP P N+INGGSHA N + QEFMI+PVGA +F++A Sbjct: 122 AADYLEVPLYHY---LGGFNTKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKEA 178 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R+GAEV+H L ++K + AT+VGDEGGFAPN+ N E E++ EAI+KAGY + Sbjct: 179 LRMGAEVFHALAAILKSR--GLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGKD 236 Query: 240 IVIGMDVAASEFY--RDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFD 297 +V+ MD A+SEFY G Y L + T D++ Y++ V YP++SIED D Sbjct: 237 VVLAMDAASSEFYDKEKGVYVLADSGEGEK----TTDEMIKFYEELVSKYPIISIEDGLD 292 Query: 298 QDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQ 355 ++DW + K T +G +Q+VGDDL VTN +++ +E+ N +L+KVNQIG++TE + Sbjct: 293 ENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIANSILIKVNQIGTLTETFE 352 Query: 356 ACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+E G+ +VSHRSGETED+ I+D+ V GQIKTG+ R++R+AKYNQL+RIE+ Sbjct: 353 AIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIED 412 Query: 416 ELGDEARFAG-HNFRN 430 +LG+ A + G +F N Sbjct: 413 QLGEVAEYKGLKSFYN 428 >5J04-A nrPDB Length = 425 Score = 419 bits (1078), Expect = e-118, Method: Compositional matrix adjust. Identities = 229/428 (53%), Positives = 291/428 (67%), Gaps = 20/428 (4%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKG-LFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I +I AREILDSRG PTVE +++ G + A VPSGASTG +EA ELRD D RY GKG Sbjct: 5 IAEITAREILDSRGRPTVEAEVHLEDGSVGLAQVPSGASTGTFEAHELRDDDPSRYGGKG 64 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV+++ S I ALI GLS ++QE LD M+ LDGT NK GANAIL VSLA A Sbjct: 65 VQKAVENV-SAIEDALI--GLSALDQEGLDKAMIALDGTPNKKNLGANAILAVSLATAHA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A LPLYR++ N +LPVP NVINGG+HA N + QEFMI+PVGA SF++A Sbjct: 122 AATSLNLPLYRYLGGPLAN---VLPVPMMNVINGGAHADNNVDFQEFMIMPVGAPSFKEA 178 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R GAEV+H L V+KDK AT VGDEGGFAPN+ N EALEL+ AI+ AGY E+ Sbjct: 179 LRWGAEVFHALAKVLKDK--GLATGVGDEGGFAPNLGSNKEALELLLTAIEAAGYKPGEQ 236 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 + + MDVA+SEFY++G Y D S +P+ I + D V YP+VSIED +D Sbjct: 237 VALAMDVASSEFYKNGLYTCDGVS-HEPAGMI------GILADLVSQYPIVSIEDGLQED 289 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 DW+ W T +G +Q+VGDDL VTNP R++ +E+ N +L+K+NQIG++TE ++ Sbjct: 290 DWSNWKTLTQQLGSTVQLVGDDLFVTNPDRLQSGIEQGVGNAVLIKLNQIGTLTETLRTI 349 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 LA +G+ ++SHRSGETEDT IADL V GQIKTG+ RSER+AKYN+L+RIE L Sbjct: 350 DLATRSGYRSVISHRSGETEDTTIADLAVATRAGQIKTGSLSRSERIAKYNRLLRIEAAL 409 Query: 418 GDEARFAG 425 G+ A +AG Sbjct: 410 GENALYAG 417 >5BOE-A nrPDB Length = 442 Score = 417 bits (1072), Expect = e-117, Method: Compositional matrix adjust. Identities = 216/434 (49%), Positives = 298/434 (68%), Gaps = 12/434 (2%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPTVEV++ T G F RA VPSGASTG +EA+ELRDGDK RYLGKG Sbjct: 4 ITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKG 63 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV+++N IAP +I SV++Q +D +M+ LDGT NK K GANAILGVS+AV +A Sbjct: 64 VTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARA 123 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A PLY+++ G LPVP N++NGGSH+ +A QEFMILPVGA +F+++ Sbjct: 124 AADLLGQPLYKYLGGFNGKQ---LPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKES 180 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R G E++H LK ++ K G + T VGDEGGFAP +A+E + +AI+ AGY E+ Sbjct: 181 LRWGTEIFHNLKSILS-KRGLE-TAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEE 238 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 + +G D A+SEFY +G YD ++ +Q+ L Q V YP+++IED D++ Sbjct: 239 VFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQ-LVDKYPIITIEDGMDEN 297 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 DW W + T +G +Q+VGDDL VTN + + + +E N +L+KVNQIG++TE A Sbjct: 298 DWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAI 357 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 ++AQ+ G+ +VSHRSGETEDT IAD+ V GQIKTG+ R++R+AKYNQL+RIE+EL Sbjct: 358 EMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDEL 417 Query: 418 GDEARFAG-HNFRN 430 + A++ G +F N Sbjct: 418 FETAKYDGIKSFYN 431 >6BFZ-A nrPDB Length = 449 Score = 416 bits (1070), Expect = e-117, Method: Compositional matrix adjust. Identities = 227/429 (52%), Positives = 299/429 (69%), Gaps = 14/429 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I KI REI+DSRGNPTVE +++ G AA PSGASTG EALELRDGDK R+LGKG Sbjct: 21 IVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKG 80 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV +N IA ALI G +Q +D +M++LDGTENKSKFGANAIL VSLA KA Sbjct: 81 VTKAVAAVNGPIAQALI--GKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKA 138 Query: 122 GAAERELPLYRHIAQLAGN-SDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 AA + +PLY HIA+L G +PVP N+INGG HA N + +QEFMI PVGA++ ++ Sbjct: 139 AAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKE 198 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--E 238 A+R+G+EV+H L V+K K G + T VGDEGG+APN+ N+EAL ++ EA+ AGY + Sbjct: 199 AIRMGSEVFHHLAKVLKAK-GMN-TAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGK 256 Query: 239 KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I + MD AASEFY+DGKY L + ++ T ++ ++ + YP+VSIED D+ Sbjct: 257 DITLAMDCAASEFYKDGKYVL----AGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDE 312 Query: 299 DDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 DW ++ T +G IQ+VGDDL VTN K ++ +E+ N +L+K NQIGS+TE + A Sbjct: 313 SDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAA 372 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 K+A++ G+ ++SHRSGETED IADL VG GQIKTG+ RS+R+AKYNQL+RIEE Sbjct: 373 IKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEA 432 Query: 417 LGDEARFAG 425 LG++A + G Sbjct: 433 LGEKAPYNG 441 >6NB2-A nrPDB Length = 430 Score = 412 bits (1058), Expect = e-115, Method: Compositional matrix adjust. Identities = 217/416 (52%), Positives = 283/416 (68%), Gaps = 17/416 (4%) Query: 5 KIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKGVL 63 KI AREILDSRGNPT+E D+ G+ RA+VPSGASTG EA ELRD D +RY GKGV Sbjct: 13 KIQAREILDSRGNPTIEADVTLTTGIIGRASVPSGASTGSREACELRDNDPKRYAGKGVQ 72 Query: 64 KAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGA 123 KAV H+N+ I AL GLSV +QE LD ++ +LD TENKS GANAIL SLA +A A Sbjct: 73 KAVKHVNNEINQAL--QGLSVEDQENLDRILCQLDNTENKSHLGANAILATSLACARARA 130 Query: 124 AERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMR 183 PLY + Q + +PVP N++NGG+HA N + +QEFMI+P+GA F A++ Sbjct: 131 LSLNQPLYMTLNQ---GDMMTMPVPMMNILNGGAHADNNVDIQEFMIMPIGAPDFPVALQ 187 Query: 184 LGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKIV 241 +G E++H LK V+K K G + T VGDEGGFAPNI N +AL+L+ EAI+KAG+ E IV Sbjct: 188 MGTEIFHVLKSVLK-KQGLN-TAVGDEGGFAPNIQSNRQALDLLSEAIEKAGFRLGEDIV 245 Query: 242 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 +DVAASE + +G Y + ++ QL Y + + YP+VSIED D+ DW Sbjct: 246 FALDVAASELFNEGFYHM-----YSENQKFDSHQLIEYYANLISSYPIVSIEDGLDEKDW 300 Query: 302 AAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 + W + T ++G +Q+VGDDL VTNPK + + + N +L+KVNQIG+++E QA KL Sbjct: 301 SGWKQLTTHLGNKVQLVGDDLFVTNPKILREGIAQGIANAILIKVNQIGTLSETRQAIKL 360 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A +NG+ ++SHRSGETEDTFIADL V GQIKTG+ CR++R AKYNQL+RI E Sbjct: 361 AYDNGYRCVMSHRSGETEDTFIADLAVASGCGQIKTGSLCRTDRTAKYNQLLRINE 416 >3UJ2-A nrPDB Length = 449 Score = 412 bits (1058), Expect = e-115, Method: Compositional matrix adjust. Identities = 225/432 (52%), Positives = 299/432 (69%), Gaps = 19/432 (4%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLG 59 + IEK+ REI+DSRGNPTVE ++Y A G+ R PSGASTG +EALELRDGDK R+ G Sbjct: 26 LEIEKVIGREIIDSRGNPTVEAEVYLAGGVTGRGTAPSGASTGEFEALELRDGDKGRFGG 85 Query: 60 KGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVC 119 KGV KAV +IN+ I+ L SG+ + +D M++ DGT++KSKFGANA+L VS+A Sbjct: 86 KGVTKAVQNINTEISEIL--SGMDASDIYAVDRAMIDADGTKDKSKFGANAVLAVSIACA 143 Query: 120 KAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 KA AA +PLYR + L N LPVP N++NGG+HA N + +QEFMI+PVGAESFR Sbjct: 144 KAAAAALGVPLYRFLGGLNANR---LPVPMMNILNGGAHAANTVDVQEFMIMPVGAESFR 200 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT-- 237 +A+R EV+H L G++K K AT+VGDEGGFAP++ + EA+E + EA+ AGY Sbjct: 201 EALRQCTEVFHALAGLLKSK--GLATSVGDEGGFAPDLASDEEAIEYILEAVKLAGYEPG 258 Query: 238 EKIVIGMDVAASEFY--RDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDP 295 V+ MD A+SE+ + G+Y L R ++L A ++ YP+VSIED Sbjct: 259 RDFVLAMDAASSEWKGEKKGEYIL-----PKCKRKFASEELVAHWKSLCERYPIVSIEDG 313 Query: 296 FDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEA 353 D++DW W T +G IQ+VGDDL VTN +R+ + ++E+ N +L+K+NQIG+V+E Sbjct: 314 LDEEDWEGWQYMTRELGDKIQLVGDDLFVTNTERLNKGIKERCGNSILIKLNQIGTVSET 373 Query: 354 IQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRI 413 ++A K+A + G+ +VSHRSGETEDT IADL V L TGQIKTGAP RSER+AKYNQL+RI Sbjct: 374 LEAIKMAHKAGYTAVVSHRSGETEDTTIADLAVALNTGQIKTGAPSRSERVAKYNQLLRI 433 Query: 414 EEELGDEARFAG 425 EEELGD A + G Sbjct: 434 EEELGDSAVYPG 445 >3ZLH-A nrPDB Length = 455 Score = 406 bits (1043), Expect = e-114, Method: Compositional matrix adjust. Identities = 214/437 (48%), Positives = 298/437 (68%), Gaps = 17/437 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPT+EV++YT G F R VPSGASTG +EA+ELRDGDK RYLG G Sbjct: 24 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLG 83 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 KAVD++N+ IA A+I G V +Q+ +D M+ LDGT NK K GANAILGVS+AV +A Sbjct: 84 TQKAVDNVNNIIAKAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARA 141 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A E+PLY + L G + +LP P N+INGGSH+ +A QEFMI+PVGA +F++ Sbjct: 142 AADYLEVPLYTY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEG 198 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT---E 238 +R GAEV+H LK ++K++ T VGDEGGFAP + +E + +AI+ AGY Sbjct: 199 LRWGAEVFHALKKILKER--GLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGEN 256 Query: 239 KIVIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPF 296 I+IG D A+SEFY + YD + + +Q+ L ++ V YP+++IED Sbjct: 257 GIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQVDYL-EELVNKYPIITIEDGM 315 Query: 297 DQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAI 354 D++DW W T +G +Q+VGDD VTN + + R ++E A N +L+KVNQIG++TE Sbjct: 316 DENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETF 375 Query: 355 QACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 +A ++A+E G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RIE Sbjct: 376 EAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIE 435 Query: 415 EELGDEARFAG-HNFRN 430 ++LG+ A++ G +F N Sbjct: 436 DQLGEVAQYKGIKSFYN 452 >1W6T-A nrPDB Length = 444 Score = 403 bits (1035), Expect = e-112, Method: Compositional matrix adjust. Identities = 213/436 (48%), Positives = 296/436 (67%), Gaps = 16/436 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPT+EV++YT G F R VPSGASTG +EA+ELRDGDK RY G G Sbjct: 14 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLG 73 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 KAVD++N+ IA A+I G V +Q+ +D M+ LDGT NK K GANAILGVS+AV +A Sbjct: 74 TQKAVDNVNNIIAEAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARA 131 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A E+PLY + L G + +LP P N+INGGSH+ +A QEFMILPVGA +F++A Sbjct: 132 AADYLEIPLYSY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEA 188 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R GAE++H LK ++K + G + T VGDEGGFAP + +E + AI+ AGY + Sbjct: 189 LRYGAEIFHALKKILKSR-GLE-TAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKD 246 Query: 240 IVIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFD 297 + +G D A+SEFY + YD + + +Q+ L ++ V YP+++IED D Sbjct: 247 VFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYL-EELVNKYPIITIEDGMD 305 Query: 298 QDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQ 355 ++DW W T +G +Q+VGDD VTN + R ++E A N +L+KVNQIG++TE + Sbjct: 306 ENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFE 365 Query: 356 ACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+E G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RIE+ Sbjct: 366 AIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIED 425 Query: 416 ELGDEARFAG-HNFRN 430 +LG+ A + G +F N Sbjct: 426 QLGEVAEYRGLKSFYN 441 >6O4N-A nrPDB Length = 432 Score = 389 bits (998), Expect = e-108, Method: Compositional matrix adjust. Identities = 216/430 (50%), Positives = 280/430 (65%), Gaps = 21/430 (4%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I I AREILDSRG PT+ V + T G F A VPSGASTGI EALELRD D +RY GKG Sbjct: 14 ISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGKG 73 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VL+A+ ++ + PAL G SV +Q D +M++ DGT NK K GANAILGVSLA+ KA Sbjct: 74 VLQAISNVEKVLVPAL--QGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKA 131 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A + PLYR+ L G+ +LP P N+INGG HA N L QEFMI P+ A S ++A Sbjct: 132 AANTLQRPLYRY---LGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLKEA 188 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R+GAEV++ LK +++++ + AT VGDEGGFAPN+ N+EAL+L+ AI+ AG+T E Sbjct: 189 VRMGAEVFNALKKILQNR--QLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPRED 246 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 I + +D AAS FY D KS DQ+G L + YP+ SIED ++ Sbjct: 247 ISLALDCAASSFYNTQDKTYDGKS--------YADQVGIL-AELCEHYPIDSIEDGLAEE 297 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 D+ W + +G +Q+VGDDL VTN I + + N +L+K NQIG++TE +A Sbjct: 298 DFEGWKLLSETLGDRVQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAI 357 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 +LA G+ ++SHRSGETEDT IADL V TGQIKTG+ RSER+AKYN+LM IEEE+ Sbjct: 358 RLATIQGYATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEM 417 Query: 418 GDEARFAGHN 427 G EA F N Sbjct: 418 GPEALFQDSN 427 >3TQP-A nrPDB Length = 428 Score = 386 bits (992), Expect = e-108, Method: Compositional matrix adjust. Identities = 210/429 (48%), Positives = 290/429 (67%), Gaps = 18/429 (4%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFR-AAVPSGASTGIYEALELRDGDKQRYLGK 60 +I I A EILDSR NPT+EV + + + AAVPSGASTG EA+ELRD D +RY GK Sbjct: 4 TITDINAHEILDSRANPTLEVRVTLSSQAYGCAAVPSGASTGEREAVELRDNDLERYGGK 63 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 GVL+AV+++N I AL+ G QE++D +M+ELDGTENK+ GANAILGVSLAV Sbjct: 64 GVLQAVENVNGPIRDALL--GQDPRSQEEIDRIMIELDGTENKANLGANAILGVSLAVAY 121 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A A +LPLYR++ G +PVP N+INGG+HA N L QEFMI+PVGA +F + Sbjct: 122 AAANNADLPLYRYLGGDGG--PFSMPVPMMNIINGGAHATNNLDFQEFMIVPVGAPTFAE 179 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--E 238 A+R GAEV+H LK + + A VGDEGGFAP++ N A EL+ EAI+ A Y + Sbjct: 180 ALRYGAEVFHALKKRLVSRGLMSA--VGDEGGFAPDLPNNEAAFELILEAIEDANYVPGK 237 Query: 239 KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I + +D A+SE Y++G+YD + + +T +++ ++ + YPV+SIED + Sbjct: 238 DIYLALDAASSELYQNGRYDFE-------NNQLTSEEMIDRLTEWTKKYPVISIEDGLSE 290 Query: 299 DDWAAWSKFTANV--GIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 +DWA W T + +Q+VGDD+ VTNP +E+ +++ N +L+K+NQIG++TE + Sbjct: 291 NDWAGWKLLTERLENKVQLVGDDIFVTNPDILEKGIKKNIANAILVKLNQIGTLTETLAT 350 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 LA+ N +GV++SHRSGETEDT IADL V QIKTG+ CRS+R+AKYN+L++IE E Sbjct: 351 VGLAKSNKYGVIISHRSGETEDTTIADLAVATDARQIKTGSLCRSDRVAKYNRLLQIERE 410 Query: 417 LGDEARFAG 425 L D+A +AG Sbjct: 411 LNDQAPYAG 419 >6J36-A nrPDB Length = 460 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 208/442 (47%), Positives = 287/442 (64%), Gaps = 29/442 (6%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAA-VPSGASTGIYEALELRDGDKQR----Y 57 I K++AREILDSRGNPT++VD+YT G F +A VPSGASTG EALELRD + + Y Sbjct: 4 ITKVFAREILDSRGNPTIQVDVYTLAGGFGSAIVPSGASTGSREALELRDTNTKYADNWY 63 Query: 58 LGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLA 117 KGV+ AVD++N+ IAP +I GL Q +D ++ELDGT NK K GANAILGVSLA Sbjct: 64 GQKGVMTAVDNVNNIIAPEII--GLCCKNQRLIDQKIIELDGTPNKEKLGANAILGVSLA 121 Query: 118 VCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAES 177 V KA A E +PL+R+ L G + ++PVP NVINGG HA N L QEFMI+P+G + Sbjct: 122 VAKAAANELRMPLFRY---LGGTNPTLMPVPMLNVINGGEHASNTLDFQEFMIMPLGFRT 178 Query: 178 FRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT 237 F++A++ +V+H L ++K K G + T VGDEGGFAPN + +AL+ + +AI ++G+ Sbjct: 179 FKEALQAANKVFHNLAKLLK-KSGFE-TQVGDEGGFAPNFNSHEQALDFLVDAIKESGFN 236 Query: 238 ------EKIVIGMDVAASEFYRDGKYDLD---------FKSPTDPSRYITGDQLGALYQD 282 + I +D AASEFY KY ++ D ++L Y Sbjct: 237 PGFKGENAVAIAIDAAASEFYNGQKYVFKKLKAASLSKNQADLDEKFEFNSEELLNYYGQ 296 Query: 283 FVRDYPVVSIEDPFDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCL 340 + YP++SIED F + DW + F G QIVGDDLTVTN + +++A+ KA N + Sbjct: 297 LLAKYPIISIEDGFAESDWQGFIAFNQKYGNNHQIVGDDLTVTNVEILKKAINLKAINSI 356 Query: 341 LLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCR 400 L+K+NQIG+++E + A LAQ++G ++SHRSGE+EDT IADL V + +GQIKTG+ R Sbjct: 357 LIKLNQIGTLSETLDAIHLAQKSGMTAVISHRSGESEDTTIADLAVAVSSGQIKTGSLSR 416 Query: 401 SERLAKYNQLMRIEEELGDEAR 422 ++R+AKYN+L+ IEE L A+ Sbjct: 417 TDRIAKYNRLLVIEEYLNSYAK 438 >3QN3-A nrPDB Length = 417 Score = 363 bits (931), Expect = e-100, Method: Compositional matrix adjust. Identities = 201/419 (47%), Positives = 275/419 (65%), Gaps = 18/419 (4%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAA-VPSGASTGIYEALELRDGDKQRYLG 59 + IE + A E+LDSRGNPTV+ ++ + G AA VPSGASTG EALELRD D +R+ G Sbjct: 5 LVIEDVRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDND-ERFGG 63 Query: 60 KGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVC 119 KGVLKAV ++N TIA ++ GL Q +LD+ + ELDGT N S GANA LGVS+A Sbjct: 64 KGVLKAVANVNETIADEIL--GLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATA 121 Query: 120 KAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 +A AA +PLYR+ L G + ILPVP N+INGG+HA N + QEFMI+P G SF+ Sbjct: 122 RAAAAALGMPLYRY---LGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFK 178 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEK 239 +A+R E+Y LK + + +T +GDEGGFAPN+ N+E ++L+ I KAGY + Sbjct: 179 EALRSVCEIYAILKKELANS--GHSTALGDEGGFAPNLANNTEPIDLLMTCIKKAGYENR 236 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 + I +DVA++EF++DGKY ++ K+ + + L Y + YP+ SIED ++ Sbjct: 237 VKIALDVASTEFFKDGKYHMEGKA-------FSSEALIERYVELCAKYPICSIEDGLAEN 289 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 D+ W K T +G IQ+VGDDL VTN + + +K N +L+K NQIG++T+ ++ Sbjct: 290 DFEGWIKLTEKLGNKIQLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTV 349 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 +LAQ N + ++SHRSGE+ED FIAD V L TGQIKTGA R ER AKYN+L+ IE E Sbjct: 350 RLAQRNNYKCVMSHRSGESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIEFE 408 >3R11-A nrPDB Length = 379 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE P D A ++ T I +V D+ +V + K ER ++E+ACN + +K+ + G + Sbjct: 219 IEQPVKYYDIKAMAEITKFSNIPVVADE-SVFDAKDAERVIDEQACNMINIKLAKTGGIL 277 Query: 352 EAIQACKLAQENGWGVMV 369 EA + KLA G MV Sbjct: 278 EAQKIKKLADSAGISCMV 295 >3IK4-A nrPDB Length = 365 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 288 PVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347 P+V E P ++DWA ++ TA G + D+ + + + R E + + +K+ + Sbjct: 216 PMVLFEQPLPREDWAGMAQVTAQSGFAVAADE-SARSAHDVLRIAREGTASVINIKLMKA 274 Query: 348 GSVTEAIQACKLAQENGWGVMV 369 G V E ++ +AQ G G+M+ Sbjct: 275 G-VAEGLKMIAIAQAAGLGLMI 295 >4MMW-A nrPDB Length = 405 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 36/73 (49%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE+P D+ +++ + N+ I +VG + ++ AC+ L VN +G +T Sbjct: 254 IEEPMDEQSLSSYKWLSDNLDIPVVGPESAAGKHWHRAEWIKAGACDILRTGVNDVGGIT 313 Query: 352 EAIQACKLAQENG 364 A++ LA+ G Sbjct: 314 PALKTMHLAEAFG 326 >1WUE-A nrPDB Length = 386 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 20/77 (25%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Query: 287 YPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQ 346 Y + IE PF DD+ ++ + +I D+ + + K + A+ +C + LK+ + Sbjct: 227 YQLAMIEQPFAADDFLDHAQLQRELKTRICLDE-NIRSLKDCQVALALGSCRSINLKIPR 285 Query: 347 IGSVTEAIQACKLAQEN 363 +G + EA++ QEN Sbjct: 286 VGGIHEALKIAAFCQEN 302 >4MGG-A nrPDB Length = 369 Score = 36.2 bits (82), Expect = 0.030, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 15/97 (15%) Query: 319 DLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEA--------IQACKLAQENGWG---- 366 D + P + R + E A +C+ LK++++G +T+A + E+ WG Sbjct: 243 DEVIDGPNTLVRGIAEDAMDCINLKISKVGGLTKAKLMRDLCIAHGIPMTIEDTWGGDIV 302 Query: 367 -VMVSH--RSGETEDTFIADLVVGLCTGQIKTGAPCR 400 ++H RS +E TF A T I GAP R Sbjct: 303 TAAIAHLARSTPSEFTFSATDFNSYGTVDIAEGAPKR 339 >3S5S-A nrPDB Length = 389 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 V +E P +DDW + T G+ + D+ + + + R E+A + +K+ + G Sbjct: 218 VALLEQPVPRDDWDGMKEVTRRAGVDVAADESAASA-EDVLRVAAERAATVVNIKLMK-G 275 Query: 349 SVTEAIQACKLAQENGWGVMV 369 + EA+ +A+ G G+M+ Sbjct: 276 GIAEALDIAAVARAAGLGLMI 296 >3UXL-A nrPDB Length = 383 Score = 33.1 bits (74), Expect = 0.25, Method: Compositional matrix adjust. Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 4/95 (4%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQI-VGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347 V IE+P Q D+ + + + + + +G++ P+ + +A+ AC + +I Sbjct: 241 VTWIEEPTLQHDYEGHQRIQSKLNVPVQMGENWL--GPEEMFKALSIGACRLAMPDAMKI 298 Query: 348 GSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIA 382 G VT I+A LAQ+ G M SH E +A Sbjct: 299 GGVTGWIRASALAQQFGIP-MSSHLFQEISAHLLA 332 >5X3E-A nrPDB Length = 449 Score = 31.6 bits (70), Expect = 0.70, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 2/71 (2%) Query: 229 EAIDKAGYTEKIVIGMDVAASEFYRDGKYDL--DFKSPTDPSRYITGDQLGALYQDFVRD 286 EAI +GY + +V + V E Y + YDL D ++ R I D+ +Y D +D Sbjct: 202 EAIKLSGYNDDMVCSVFVTYVEIYNNYCYDLLEDARNGVLTKREIRHDRQQQMYVDGAKD 261 Query: 287 YPVVSIEDPFD 297 V S E+ + Sbjct: 262 VEVSSSEEALE 272 >2Z8X-A nrPDB Length = 617 Score = 31.2 bits (69), Expect = 0.91, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 20/94 (21%) Query: 178 FRDAMRLGAEVYHTLKGVIKDKYGKDATNVG-------------DEGGFAPNILENSEAL 224 F DAM + YH L Y + +G D G P I N ++ Sbjct: 18 FSDAMAITLYSYHNLDNGFAAGYQHNGFGLGLPATLVTALLGGTDSQGVIPGIPWNPDSE 77 Query: 225 ELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYD 258 +L +A+ KAG+T + AS+ DGK D Sbjct: 78 KLALDAVKKAGWTP-------ITASQLGYDGKTD 104 >3QLD-A nrPDB Length = 388 Score = 31.2 bits (69), Expect = 0.92, Method: Compositional matrix adjust. Identities = 54/216 (25%), Positives = 84/216 (38%), Gaps = 39/216 (18%) Query: 218 LENSEALELVKEAIDKA---GYTE---KIVIGMDVAASEFYRDGKYDL----DFKSPTDP 267 L SE+L+++ +++D A G+ KI G D AA + R DL D P Sbjct: 144 LGMSESLDVLIQSVDAAVEQGFRRVKLKIAPGRDRAAIKAVRLRYPDLAIAADANGSYRP 203 Query: 268 SRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKR 327 QL A Y + IE P +DDW +K A++ + D+ +V + + Sbjct: 204 EDAPVLRQLDA--------YDLQFIEQPLPEDDWFDLAKLQASLRTPVCLDE-SVRSVRE 254 Query: 328 IERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVG 387 ++ A L +K ++G ++A +A E G M + G E VG Sbjct: 255 LKLTARLGAARVLNVKPGRLGGFGATLRALDVAGEAG---MAAWVGGMYETG------VG 305 Query: 388 LCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARF 423 G I P LMR +LG R+ Sbjct: 306 RVHGLIAAALP-----------LMRYATDLGPSDRY 330 >4JMP-A nrPDB Length = 269 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 264 PTDPSRYITGDQLGALYQDFVRDYPVVSIEDP--FDQDDWAAWSKFTANV 311 P +PS IT LY + +Y V I+ P D +SKFT NV Sbjct: 167 PPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNV 216 >3JW7-A nrPDB Length = 354 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 14/167 (8%) Query: 215 PNILENSEALELVKEAIDKAGYTEKIVIGM----DVAASEFYRDGKYDLDFKSPTDPSR- 269 PN++ +A+E VK D T KI +G D+A + R+ D K D ++ Sbjct: 140 PNVMAQ-KAVEKVKLGFD----TLKIKVGTGIEADIARVKAIREA-VGFDIKLRLDANQA 193 Query: 270 YITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIE 329 + D + A+ + DY + +E P + D T+ V I+ D+ +E Sbjct: 194 WTPKDAVKAIQA--LADYQIELVEQPVKRRDLEGLKYVTSQVNTTIMADESCFDAQDALE 251 Query: 330 RAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGET 376 V++ + + +K+ + G + EA++ ++ + G M+ + ET Sbjct: 252 -LVKKGTVDVINIKLMKCGGIHEALKINQICETAGIECMIGCMAEET 297 >1TKK-A nrPDB Length = 366 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 +E P +DD A K T I+ D+ +V P++ ++ ++ + + +K+ + G ++ Sbjct: 218 VEQPVHKDDLAGLKKVTDATDTPIMADE-SVFTPRQAFEVLQTRSADLINIKLMKAGGIS 276 Query: 352 EAIQACKLAQENGWGVMV 369 A + +A+ G MV Sbjct: 277 GAEKINAMAEACGVECMV 294 >2PGE-A nrPDB Length = 377 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGD-DLTVTNPKRIERAVEEKACNCLLL 342 + + + SIE P Q W+ + AN + I D +L ++ ++ ++L Sbjct: 231 LSQFHLHSIEQPIRQHQWSEMAALCANSPLAIALDEELIGLGAEQRSAMLDAIRPQYIIL 290 Query: 343 KVNQIGSVTEAIQACKLAQENGWGVMVS 370 K + +G A Q +LA+E G G ++ Sbjct: 291 KPSLLGGFHYAGQWIELARERGIGFWIT 318 >2YCB-A nrPDB Length = 636 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 194 GVIKDKYGKDATNVGDEGGFAPNILE----NSEALELVKEAIDKAGYTEKIVIGMDVAAS 249 G++ KYG + + G+AP IL +SE +E ++ + K K ++ + Sbjct: 110 GLVIGKYGSTSREIVKNTGWAPKILRTPPISSEIIERIRRTLRKNSKERKKILQQ--LGN 167 Query: 250 EFYRDGKYDLDF 261 ++ KYD D+ Sbjct: 168 RIHQKPKYDNDW 179 >5DMB-A nrPDB Length = 151 Score = 28.5 bits (62), Expect = 6.1, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 14/85 (16%) Query: 257 YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANV----G 312 Y++D T ITG+Q ALY ++++ DPFD + NV G Sbjct: 70 YEIDLDDNTLEQLQITGEQDVALYV-------ILTVADPFDDTTANLQAPIVINVHKRLG 122 Query: 313 IQIVGDDLTVTNPKRIERAVEEKAC 337 Q++ LT TN K R EK Sbjct: 123 KQVI---LTNTNYKTKHRLFPEKVA 144 >2E2P-A nrPDB Length = 299 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 11/90 (12%) Query: 210 EGGFAPNILEN---SEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSP-- 264 EG P N + A+E +KEA+ A E V+GM VA D K+D + +P Sbjct: 28 EGSSGPGNYHNVGLTRAIENIKEAVKIAAKGEADVVGMGVAG----LDSKFDWENFTPLA 83 Query: 265 --TDPSRYITGDQLGALYQDFVRDYPVVSI 292 P I D + AL+ + + + VV I Sbjct: 84 SLIAPKVIIQHDGVIALFAETLGEPGVVVI 113 >5HQA-A nrPDB Length = 669 Score = 28.1 bits (61), Expect = 7.2, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 23/43 (53%) Query: 282 DFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTN 324 D+ + V S P+D D AA +K++ G+Q++G T N Sbjct: 320 DWFFNGDVFSFTQPYDDFDIAALTKYSKQTGVQLIGHHETSGN 362 >5AOU-A nrPDB Length = 258 Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust. Identities = 11/36 (30%), Positives = 21/36 (58%) Query: 224 LELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDL 259 L++ ++ I+ A Y E +G+ + E Y DG Y++ Sbjct: 60 LDVERDPIEYAKYMEPYAVGLSIKTEEKYFDGSYEM 95 >3MV5-A nrPDB Length = 342 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 18/70 (25%) Query: 53 DKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAIL 112 D+ R+ G ++ A+D+++S V KL+NLML+ DG + FG Sbjct: 110 DRARFYGAEIVSALDYLHSEKN--------VVYRDLKLENLMLDKDGHIKITDFG----- 156 Query: 113 GVSLAVCKAG 122 +CK G Sbjct: 157 -----LCKEG 161 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3UJR-A nrPDB 742 0.0 2XSX-A nrPDB 720 0.0 3B97-A nrPDB 720 0.0 1PDZ-A nrPDB 697 0.0 3QTP-A nrPDB 673 0.0 5WRO-A nrPDB 672 0.0 4G7F-A nrPDB 656 0.0 2PU1-A nrPDB 653 0.0 3OTR-A nrPDB 651 0.0 2XH7-A nrPDB 642 0.0 5BOE-A nrPDB 637 0.0 4A3R-A nrPDB 633 0.0 1IYX-A nrPDB 631 0.0 4MKS-A nrPDB 631 0.0 3ZLH-A nrPDB 629 0.0 1W6T-A nrPDB 628 e-180 2PA6-A nrPDB 610 e-175 4Z1Y-A nrPDB 608 e-174 5J04-A nrPDB 596 e-171 6NB2-A nrPDB 596 e-171 3TQP-A nrPDB 587 e-168 6BFZ-A nrPDB 584 e-167 3UJ2-A nrPDB 583 e-167 6O4N-A nrPDB 573 e-164 6J36-A nrPDB 559 e-159 3QN3-A nrPDB 558 e-159 3R11-A nrPDB 98 6e-21 3IK4-A nrPDB 86 4e-17 Sequences not found previously or not previously below threshold: 3JW7-A nrPDB 67 2e-11 3QLD-A nrPDB 59 4e-09 3S5S-A nrPDB 58 7e-09 1TKK-A nrPDB 57 1e-08 1WUE-A nrPDB 55 7e-08 2ZC8-A nrPDB 53 2e-07 3U9I-A nrPDB 53 2e-07 2GGG-A nrPDB 53 3e-07 2QDE-A nrPDB 53 3e-07 3MY9-A nrPDB 51 1e-06 3I6E-A nrPDB 50 2e-06 3I4K-A nrPDB 50 2e-06 3DFY-A nrPDB 49 5e-06 3IJQ-A nrPDB 48 7e-06 2P8B-A nrPDB 48 8e-06 4MMW-A nrPDB 48 8e-06 3Q4D-A nrPDB 48 1e-05 4HNL-A nrPDB 47 1e-05 1WUF-A nrPDB 46 3e-05 1NU5-A nrPDB 46 4e-05 5FJT-A nrPDB 46 4e-05 3R25-A nrPDB 45 6e-05 2PGW-A nrPDB 45 7e-05 4GFI-A nrPDB 44 1e-04 3S47-A nrPDB 42 6e-04 3RO6-B nrPDB 41 0.001 3MWC-A nrPDB 40 0.002 1JPD-X nrPDB 39 0.003 3UXL-A nrPDB 39 0.003 4MGG-A nrPDB 39 0.003 4GIR-A nrPDB 39 0.003 3TTE-A nrPDB 38 0.008 3UGV-A nrPDB 38 0.008 2QVH-A nrPDB 38 0.009 4M0X-A nrPDB 38 0.010 3I6T-A nrPDB 37 0.013 1MUC-A nrPDB 37 0.017 2CHR-A nrPDB 37 0.020 2OG9-A nrPDB 36 0.025 3FCP-A nrPDB 36 0.028 5X3E-A nrPDB 36 0.031 3TJI-A nrPDB 36 0.035 5HQA-A nrPDB 36 0.044 2PP0-A nrPDB 36 0.045 3DGB-A nrPDB 35 0.056 3TW9-A nrPDB 34 0.093 3ZVH-B nrPDB 34 0.097 3ES8-A nrPDB 34 0.14 3T6C-A nrPDB 34 0.14 3T8Q-A nrPDB 34 0.16 2PGE-A nrPDB 33 0.26 4IHC-A nrPDB 33 0.37 4PG8-A nrPDB 32 0.56 3EKG-A nrPDB 31 0.75 4A35-A nrPDB 31 0.76 3A04-A nrPDB 31 1.0 2Z8X-A nrPDB 31 1.2 3G68-A nrPDB 31 1.2 1FHV-A nrPDB 30 1.7 1KKR-A nrPDB 30 1.8 5XD7-A nrPDB 30 2.1 3H7V-A nrPDB 30 2.3 3ERV-A nrPDB 29 3.0 3SJN-A nrPDB 29 3.0 4WMZ-A nrPDB 29 3.1 6ILH-A nrPDB 29 3.2 4IL2-A nrPDB 29 3.6 5KR3-A nrPDB 29 4.0 5OLC-A nrPDB 29 4.3 6CHD-A nrPDB 29 4.4 3K4W-A nrPDB 29 5.5 3GC2-A nrPDB 28 6.4 3U14-A nrPDB 28 7.7 1X94-A nrPDB 28 8.0 3DDM-A nrPDB 28 8.4 3AGK-A nrPDB 28 8.4 6MRP-B nrPDB 28 8.6 5KR5-A nrPDB 28 9.0 3VCN-A nrPDB 28 9.0 >3UJR-A nrPDB Length = 443 Score = 742 bits (1916), Expect = 0.0, Method: Composition-based stats. Identities = 433/433 (100%), Positives = 433/433 (100%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG Sbjct: 1 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 60 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA Sbjct: 121 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 180 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 241 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV Sbjct: 181 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 240 Query: 242 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 300 Query: 302 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 361 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ Sbjct: 301 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 360 Query: 362 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 421 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA Sbjct: 361 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 420 Query: 422 RFAGHNFRNPSVL 434 RFAGHNFRNPSVL Sbjct: 421 RFAGHNFRNPSVL 433 >2XSX-A nrPDB Length = 435 Score = 720 bits (1859), Expect = 0.0, Method: Composition-based stats. Identities = 362/431 (83%), Positives = 398/431 (92%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 M+++KI+AREILDSRGNPTVEVDL+TAKG FRAAVPSGASTGIYEALELRDGDK RYLGK Sbjct: 2 MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGK 61 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 GVLKAV++INST+ PAL+ LSV +QEK+D M+ELDGTENKSKFGANAILGVSLAVCK Sbjct: 62 GVLKAVENINSTLGPALLQKKLSVADQEKVDKFMIELDGTENKSKFGANAILGVSLAVCK 121 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 AGAAE+ +PLYRHIA LAGN DLILPVPAFNVINGGSHAGNKLAMQEFMILPVGA SF++ Sbjct: 122 AGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKE 181 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 AMR+GAEVYH LKGVIK KYGKDATNVGDEGGFAPNILEN+EALEL+K AI AGY +K+ Sbjct: 182 AMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKV 241 Query: 241 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDD 300 VIGMDVAASEFYR+GKYDLDFKSP DP+R+ITG++LG LY+ F+++YPVVSIEDPFDQDD Sbjct: 242 VIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDD 301 Query: 301 WAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA 360 WA W+ F + V IQIVGDDLTVTNPKRI +AVE+KACNCLLLKVNQIGSVTE+IQACKLA Sbjct: 302 WATWTSFLSGVNIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLA 361 Query: 361 QENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDE 420 Q NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE LGD+ Sbjct: 362 QSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDK 421 Query: 421 ARFAGHNFRNP 431 A FAG FRNP Sbjct: 422 AIFAGRKFRNP 432 >3B97-A nrPDB Length = 433 Score = 720 bits (1858), Expect = 0.0, Method: Composition-based stats. Identities = 361/430 (83%), Positives = 395/430 (91%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 SI KI AREI DSRGNPTVEVDL+T+KGLFRAAVPSGASTGIYEALELRD DK RY+GKG Sbjct: 1 SILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKG 60 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV+HIN TIAPAL+S L+V EQEK+D LM+E+DGTENKSKFGANAILGVSLAVCKA Sbjct: 61 VSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKA 120 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 GA E+ +PLYRHIA LAGNS++ILPVPAFNVINGGSHAGNKLAMQEFMILPVGA +FR+A Sbjct: 121 GAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREA 180 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 241 MR+GAEVYH LK VIK+KYGKDATNVGDEGGFAPNILEN E LEL+K AI KAGYT+K+V Sbjct: 181 MRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVV 240 Query: 242 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 IGMDVAASEF+R GKYDLDFKSP DPSRYI+ DQL LY+ F++DYPVVSIEDPFDQDDW Sbjct: 241 IGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDW 300 Query: 302 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 361 AW KFTA+ GIQ+VGDDLTVTNPKRI +AV EK+CNCLLLKVNQIGSVTE++QACKLAQ Sbjct: 301 GAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQ 360 Query: 362 ENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEA 421 NGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQL+RIEEELG +A Sbjct: 361 ANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKA 420 Query: 422 RFAGHNFRNP 431 +FAG NFRNP Sbjct: 421 KFAGRNFRNP 430 >1PDZ-A nrPDB Length = 434 Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats. Identities = 317/433 (73%), Positives = 360/433 (83%), Gaps = 2/433 (0%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 SI K++AR I DSRGNPTVEVDLYT+KGLFRAAVPSGASTG++EALE+RDGDK +Y GK Sbjct: 2 SITKVFARTIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGVHEALEMRDGDKSKYHGKS 61 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V AV ++N I P +I SGL V +Q++ D M +LDGTENKS GANAILGVSLA+CKA Sbjct: 62 VFNAVKNVNDVIVPEIIKSGLKVTQQKECDEFMCKLDGTENKSSLGANAILGVSLAICKA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 GAAE +PLYRHIA LA ++ILPVPAFNVINGGSHAGNKLAMQEFMILP GA SF +A Sbjct: 122 GAAELGIPLYRHIANLANYDEVILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEA 181 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIV 241 MR+G EVYH LK VIK ++G DAT VGDEGGFAPNIL N +AL+L++EAI KAGYT KI Sbjct: 182 MRMGTEVYHHLKAVIKARFGLDATAVGDEGGFAPNILNNKDALDLIQEAIKKAGYTGKIE 241 Query: 242 IGMDVAASEFYRDGK-YDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 IGMDVAASEFY+ YDLDFK+ D S+ I+GDQL +Y +F +D+P+VSIEDPFDQD Sbjct: 242 IGMDVAASEFYKQNNIYDLDFKTANNDGSQKISGDQLRDMYMEFCKDFPIVSIEDPFDQD 301 Query: 300 DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 DW WSK T+ IQIVGDDLTVTNPKRI AVE+KAC CLLLKVNQIGSVTE+I A L Sbjct: 302 DWETWSKMTSGTTIQIVGDDLTVTNPKRITTAVEKKACKCLLLKVNQIGSVTESIDAHLL 361 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGD 419 A++NGWG MVSHRSGETED FIADLVVGLCTGQIKTGAPCRSERLAKYNQ++RIEEELG Sbjct: 362 AKKNGWGTMVSHRSGETEDCFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGS 421 Query: 420 EARFAGHNFRNPS 432 A+FAG NFR PS Sbjct: 422 GAKFAGKNFRAPS 434 >3QTP-A nrPDB Length = 441 Score = 673 bits (1736), Expect = 0.0, Method: Composition-based stats. Identities = 280/438 (63%), Positives = 344/438 (78%), Gaps = 9/438 (2%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 MSI+K+ AREILDSRGNPT+EV++ T KG+FR+ VPSGASTG++EA+ELRDGDK+RY GK Sbjct: 6 MSIQKVHAREILDSRGNPTIEVEITTGKGMFRSCVPSGASTGVHEAVELRDGDKKRYGGK 65 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 GVLKAV+++N+ I PAL+ G +V+ Q +LD +M++LDGT NK K GANAILG S+++C+ Sbjct: 66 GVLKAVENVNTIIGPALL--GKNVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICR 123 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A AAE+ LPLY+++A+L G+ ++ +PVP FNVINGG+HAGN LAMQEFMI P GA +F + Sbjct: 124 AAAAEKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHE 183 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 A+R+ AE Y LK VIK KYG+DATNVGDEGGFAPN+ EAL+L+ EAI KAGYT KI Sbjct: 184 ALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGYTGKI 243 Query: 241 VIGMDVAASEFYRD--GKYDLDFKSPT---DPSRYITGDQLGALYQDFVRDYPVVSIEDP 295 I MD AASEFY + KYDL K P DPS D L A Y D+ + YP+ SIEDP Sbjct: 244 EIAMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKHYPIASIEDP 303 Query: 296 FDQDDWAAWSKFTANVG-IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAI 354 F +DDWAAW+KFT G QIVGDDL VTNP R++ A+++ ACN +L+KVNQIG++TE Sbjct: 304 FAEDDWAAWNKFTVEHGNFQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETF 363 Query: 355 QACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 + K+AQE GWGVM SHRSGETEDTFIADLVVGL QIKTGAPCRSERL KYNQLMRIE Sbjct: 364 KTIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIE 423 Query: 415 EELGDEARFAGHNFRNPS 432 EELG +AG N+RN + Sbjct: 424 EELG-NIPYAGKNWRNST 440 >5WRO-A nrPDB Length = 439 Score = 672 bits (1735), Expect = 0.0, Method: Composition-based stats. Identities = 313/432 (72%), Positives = 362/432 (83%), Gaps = 1/432 (0%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 +I+ I AR+I DSRGNPTVEVDL T GLFRAAVPSGASTG++EALELRD DK Y GK Sbjct: 7 FTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGK 66 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 VLKAV H+N T+ P LI + L VV+Q +DN M++LDGTENKSKFGANAILGVSLAV K Sbjct: 67 SVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAK 126 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 AGAA++ +PLY+HIA LAGN ++ILPVPAFNVINGGSHAGNKLAMQEFMILP GA SF + Sbjct: 127 AGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTE 186 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 AM++G+EVYH LK VIK K+G DAT VGDEGGFAPNI N EAL L+ +AI KAGYT KI Sbjct: 187 AMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKI 246 Query: 241 VIGMDVAASEFYRDGKYDLDFKS-PTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 IGMDVAASEFY+DG+YDLDFK+ +D S+++ D+L LYQ+F++D+P+VSIEDPFDQD Sbjct: 247 EIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQD 306 Query: 300 DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 W AWS T IQIVGDDLTVTNPKRI AVE+KACNCLLLKVNQIG+VTE+I A L Sbjct: 307 HWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLL 366 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGD 419 A++NGWG MVSHRSGETED+FI DLVVGL TGQIKTGAPCRSERLAKYNQ++RIEEE+G Sbjct: 367 AKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGA 426 Query: 420 EARFAGHNFRNP 431 +FAG +FR P Sbjct: 427 GVKFAGKSFRKP 438 >4G7F-A nrPDB Length = 429 Score = 656 bits (1692), Expect = 0.0, Method: Composition-based stats. Identities = 264/427 (61%), Positives = 328/427 (76%), Gaps = 8/427 (1%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 M+I+K+ REILDSRGNPTVEV++ T G+FR+AVPSGASTGI+EA ELRD DK+RYLGK Sbjct: 1 MTIQKVHGREILDSRGNPTVEVEVTTELGVFRSAVPSGASTGIHEACELRDDDKRRYLGK 60 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 G L AV ++N +APAL+ G ++Q LD LM +LDGT NKSK GANAILG S+A+ K Sbjct: 61 GCLNAVKNVNDVLAPALV--GKDELQQSTLDKLMRDLDGTPNKSKLGANAILGCSMAISK 118 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A AA + +PLYR++A+LAG ++ LPVP FNVINGG HAGN L QEFMI PV A SF + Sbjct: 119 AAAARKGVPLYRYLAELAGTKEVRLPVPCFNVINGGKHAGNALPFQEFMIAPVKAGSFNE 178 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 A+R+GAEVYH+LK +IK KYG+DA NVGDEGGFAP I + +E L ++ EAI++AG+ + Sbjct: 179 ALRMGAEVYHSLKSIIKKKYGQDAVNVGDEGGFAPPITDINEPLPILMEAIEQAGHKGRF 238 Query: 241 VIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I MD AASE Y + K Y+L FKSP + ++T QL Y +V +YP+VS+EDP+DQ Sbjct: 239 AICMDSAASETYDENKKQYNLTFKSPE--ATWVTAKQLAETYAKWVSEYPIVSLEDPYDQ 296 Query: 299 DDWAAWSKFTANV--GIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 DD+ ++ T + Q+VGDDLTVTN RI+ A+E+KACN LLLK+NQIG++TEAI+A Sbjct: 297 DDFDGFAGITEALKGKAQVVGDDLTVTNVSRIKTAIEKKACNSLLLKINQIGTITEAIEA 356 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 K NGW VMVSHRSGETEDT+IADLVVGL TGQIKTGAPCR ER AK NQL+RIEEE Sbjct: 357 SKFCMSNGWSVMVSHRSGETEDTYIADLVVGLGTGQIKTGAPCRGERTAKLNQLLRIEEE 416 Query: 417 LGDEARF 423 LG A+F Sbjct: 417 LGAHAKF 423 >2PU1-A nrPDB Length = 432 Score = 653 bits (1686), Expect = 0.0, Method: Composition-based stats. Identities = 268/427 (62%), Positives = 332/427 (77%), Gaps = 8/427 (1%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 M+I+K+ RE+LDSRGNPTVEV++ T KG+FR+AVPSGASTG+YEA ELRDGDK+RY+GK Sbjct: 4 MTIQKVHGREVLDSRGNPTVEVEVTTEKGVFRSAVPSGASTGVYEACELRDGDKKRYVGK 63 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 G L+AV ++N I PALI G ++QE+LD LML LDGT NK K GANAILG S+A+ K Sbjct: 64 GCLQAVKNVNEVIGPALI--GRDELKQEELDTLMLRLDGTPNKGKLGANAILGCSMAISK 121 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A AA + +PLYR++A LAG +L LPVP FNVINGG HAGN L QEFMI PV A SF + Sbjct: 122 AAAAAKGVPLYRYLASLAGTKELRLPVPCFNVINGGKHAGNALPFQEFMIAPVKATSFSE 181 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 A+R+G+EVYH+L+G+IK KYG+DA NVGDEGGFAP I + +E L ++ EAI++AG+ K Sbjct: 182 ALRMGSEVYHSLRGIIKKKYGQDAVNVGDEGGFAPPIKDINEPLPILMEAIEEAGHRGKF 241 Query: 241 VIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I MD AASE Y + K Y+L FKSP ++T +QL Y + DYP+VSIEDP+DQ Sbjct: 242 AICMDCAASETYDEKKQQYNLTFKSPE--PTWVTAEQLRETYCKWAHDYPIVSIEDPYDQ 299 Query: 299 DDWAAWSKFTANV--GIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 DD+A ++ T + QIVGDDLTVTN +RI+ A+E+KACN LLLK+NQIG+++EAI + Sbjct: 300 DDFAGFAGITEALKGKTQIVGDDLTVTNTERIKMAIEKKACNSLLLKINQIGTISEAIAS 359 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 KL ENGW VMVSHRSGETEDT+IADLVV L +GQIKTGAPCR ER AK NQL+RIEEE Sbjct: 360 SKLCMENGWSVMVSHRSGETEDTYIADLVVALGSGQIKTGAPCRGERTAKLNQLLRIEEE 419 Query: 417 LGDEARF 423 LG A+F Sbjct: 420 LGAHAKF 426 >3OTR-A nrPDB Length = 452 Score = 651 bits (1680), Expect = 0.0, Method: Composition-based stats. Identities = 283/444 (63%), Positives = 352/444 (79%), Gaps = 15/444 (3%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGK 60 + I+ I AREILDSRGNPT+EVD+ T G+FRAAVPSGASTGIYEALELRD D +RYLGK Sbjct: 2 VVIKDIVAREILDSRGNPTIEVDVSTEGGVFRAAVPSGASTGIYEALELRDKDPKRYLGK 61 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLE-LDGTEN-----KSKFGANAILGV 114 GVL AV+ + I PAL+ G +Q+ +D LM+E LDGT+N KSK GANAILGV Sbjct: 62 GVLNAVEIVRQEIKPALL--GKDPCDQKGIDMLMVEQLDGTKNEWGYSKSKLGANAILGV 119 Query: 115 SLAVCKAGAAERELPLYRHIAQLAGN--SDLILPVPAFNVINGGSHAGNKLAMQEFMILP 172 S+A C+AGAA + LPLY++IA LAG +++PVP FNVINGG HAGN LA+QEF+I P Sbjct: 120 SIACCRAGAASKGLPLYKYIATLAGKTIDKMVMPVPFFNVINGGEHAGNGLALQEFLIAP 179 Query: 173 VGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAID 232 VGA + R+A+R G+E YH LK VIK+KYG DATNVGDEGGFAPN+ EAL L+ EAI Sbjct: 180 VGAPNIREAIRYGSETYHHLKNVIKNKYGLDATNVGDEGGFAPNVATAEEALNLLVEAIK 239 Query: 233 KAGYTEKIVIGMDVAASEFYR--DGKYDLDFKSPT-DPSRYITGDQLGALYQDFVRDYPV 289 AGY KI I D AASEFY+ + KYDLD+K T + S+++TG++L +Y+ +++ YP+ Sbjct: 240 AAGYEGKIKIAFDAAASEFYKQDEKKYDLDYKCKTKNASKHLTGEKLKEVYEGWLKKYPI 299 Query: 290 VSIEDPFDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347 +S+EDPFDQDD+A++S FT +VG Q++GDD+ VTN RIE+A+++KACNCLLLKVNQI Sbjct: 300 ISVEDPFDQDDFASFSAFTKDVGEKTQVIGDDILVTNILRIEKALKDKACNCLLLKVNQI 359 Query: 348 GSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKY 407 GSVTEAI+AC LAQ++GWGV VSHRSGETED+FIADLVVGL GQIK+G+PCRSERL KY Sbjct: 360 GSVTEAIEACLLAQKSGWGVQVSHRSGETEDSFIADLVVGLRCGQIKSGSPCRSERLCKY 419 Query: 408 NQLMRIEEELGDEARFAGHNFRNP 431 NQLMRIEE LG + +AG +FR+P Sbjct: 420 NQLMRIEESLGADCVYAGESFRHP 443 >2XH7-A nrPDB Length = 443 Score = 642 bits (1657), Expect = 0.0, Method: Composition-based stats. Identities = 269/430 (62%), Positives = 339/430 (78%), Gaps = 3/430 (0%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 ++ K++AR + DSRGNPTVEV+L T KG+FR+ VPSGASTG++EALE+RDGDK +++GKG Sbjct: 1 AVSKVYARSVYDSRGNPTVEVELTTEKGVFRSIVPSGASTGVHEALEMRDGDKSKWMGKG 60 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VL AV ++N IAPA + + + V +Q+ +D+ ++ LDGT NKSK GANAILGVSLA +A Sbjct: 61 VLHAVKNVNDVIAPAFVKANIDVKDQKAVDDFLISLDGTANKSKLGANAILGVSLAASRA 120 Query: 122 GAAERELPLYRHIAQLAG--NSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 AAE+ +PLY+H+A L+ S +LPVP NV+NGGSHAG LA+QEFMI P GA++F Sbjct: 121 AAAEKNVPLYKHLADLSKSKTSPYVLPVPFLNVLNGGSHAGGALALQEFMIAPTGAKTFA 180 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEK 239 +A+R+G+EVYH LK + K +YG A NVGDEGG APNI EAL+L+ +AI AG+ K Sbjct: 181 EALRIGSEVYHNLKSLTKKRYGASAGNVGDEGGVAPNIQTAEEALDLIVDAIKAAGHDGK 240 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSP-TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I IG+D A+SEF++DGKYDLDFK+P +D S+++TG QL LY ++ YP+VSIEDPF + Sbjct: 241 IKIGLDCASSEFFKDGKYDLDFKNPNSDKSKWLTGPQLADLYHSLMKRYPIVSIEDPFAE 300 Query: 299 DDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 DDW AWS F GIQIV D LTVTNPKRI A+E+KA + LLLKVNQIG+++E+I+A + Sbjct: 301 DDWEAWSHFFKTAGIQIVADALTVTNPKRIATAIEKKAADALLLKVNQIGTLSESIKAAQ 360 Query: 359 LAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELG 418 + GWGVMVSHRSGETEDTFIADLVVGL TGQIKTGAP RSERLAK NQL+RIEEELG Sbjct: 361 DSFAAGWGVMVSHRSGETEDTFIADLVVGLRTGQIKTGAPARSERLAKLNQLLRIEEELG 420 Query: 419 DEARFAGHNF 428 D A FAG NF Sbjct: 421 DNAVFAGENF 430 >5BOE-A nrPDB Length = 442 Score = 637 bits (1643), Expect = 0.0, Method: Composition-based stats. Identities = 213/434 (49%), Positives = 296/434 (68%), Gaps = 12/434 (2%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPTVEV++ T G F RA VPSGASTG +EA+ELRDGDK RYLGKG Sbjct: 4 ITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKG 63 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV+++N IAP +I SV++Q +D +M+ LDGT NK K GANAILGVS+AV +A Sbjct: 64 VTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARA 123 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A PLY++ L G + LPVP N++NGGSH+ +A QEFMILPVGA +F+++ Sbjct: 124 AADLLGQPLYKY---LGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKES 180 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R G E++H LK ++ + T VGDEGGFAP +A+E + +AI+ AGY E+ Sbjct: 181 LRWGTEIFHNLKSILSKR--GLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEE 238 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 + +G D A+SEFY +G YD ++ +Q+ + V YP+++IED D++ Sbjct: 239 VFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQV-DYLEQLVDKYPIITIEDGMDEN 297 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 DW W + T +G +Q+VGDDL VTN + + + +E N +L+KVNQIG++TE A Sbjct: 298 DWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAI 357 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 ++AQ+ G+ +VSHRSGETEDT IAD+ V GQIKTG+ R++R+AKYNQL+RIE+EL Sbjct: 358 EMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDEL 417 Query: 418 GDEARFAG-HNFRN 430 + A++ G +F N Sbjct: 418 FETAKYDGIKSFYN 431 >4A3R-A nrPDB Length = 430 Score = 633 bits (1633), Expect = 0.0, Method: Composition-based stats. Identities = 226/436 (51%), Positives = 306/436 (70%), Gaps = 20/436 (4%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPTVEV++YT G F RA VPSGASTG YEA+ELRDGDK RYLGKG Sbjct: 4 IVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGEYEAVELRDGDKDRYLGKG 63 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VL AV+++N IAP L+ G V EQ +D L++ELDGTENK K GANAILGVS+A +A Sbjct: 64 VLTAVNNVNEIIAPELL--GFDVTEQNAIDQLLIELDGTENKGKLGANAILGVSMACARA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A ++PLY++ L G + LPVP N++NGG HA N + +QEFMI+PVGA +FR+A Sbjct: 122 AADFLQIPLYQY---LGGFNSKTLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAPNFREA 178 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R+GA+++H+LK V+ K T VGDEGGFAPN+ N EAL+ + EAI+KAG+ E+ Sbjct: 179 LRMGAQIFHSLKSVLSAK--GLNTAVGDEGGFAPNLGSNEEALQTIVEAIEKAGFKPGEE 236 Query: 240 IVIGMDVAASEFYR--DGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFD 297 + + MD A+SEFY DGKY L + T ++ Y++ V YP++SIED D Sbjct: 237 VKLAMDAASSEFYNKEDGKYHLSGEGVVK-----TSAEMVDWYEELVSKYPIISIEDGLD 291 Query: 298 QDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQ 355 ++DW T +G +Q+VGDDL VTN K++ ++ N +L+KVNQIG++TE Sbjct: 292 ENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLSEGIKNGVGNSILIKVNQIGTLTETFD 351 Query: 356 ACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+ G+ ++SHRSGETED+ IAD+ V GQIKTGAP R++R+AKYNQL+RIE+ Sbjct: 352 AIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIED 411 Query: 416 ELGDEARFAGHN-FRN 430 +L + A++ G N F N Sbjct: 412 QLAETAQYHGINSFYN 427 >1IYX-A nrPDB Length = 432 Score = 631 bits (1628), Expect = 0.0, Method: Composition-based stats. Identities = 222/434 (51%), Positives = 304/434 (70%), Gaps = 15/434 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++AREILDSRGNPT+EV++YT G F R VPSGASTG YEA+ELRDGDK RY GKG Sbjct: 4 ITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYGGKG 63 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAVD++N+ IA A+I G V +Q +D M+ LDGT NK K GANAILGVS+AV +A Sbjct: 64 VTKAVDNVNNIIAEAII--GYDVRDQMAIDKAMIALDGTPNKGKLGANAILGVSIAVARA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A E+PLY + L G + +LP P N+INGGSHA N + QEFMI+PVGA +F++A Sbjct: 122 AADYLEVPLYHY---LGGFNTKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKEA 178 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R+GAEV+H L ++K + AT+VGDEGGFAPN+ N E E++ EAI+KAGY + Sbjct: 179 LRMGAEVFHALAAILKSR--GLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGKD 236 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 +V+ MD A+SEFY K + + T D++ Y++ V YP++SIED D++ Sbjct: 237 VVLAMDAASSEFYDKEKGVYVLADSGEGEK--TTDEMIKFYEELVSKYPIISIEDGLDEN 294 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 DW + K T +G +Q+VGDDL VTN +++ +E+ N +L+KVNQIG++TE +A Sbjct: 295 DWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIANSILIKVNQIGTLTETFEAI 354 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 ++A+E G+ +VSHRSGETED+ I+D+ V GQIKTG+ R++R+AKYNQL+RIE++L Sbjct: 355 EMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQL 414 Query: 418 GDEARFAG-HNFRN 430 G+ A + G +F N Sbjct: 415 GEVAEYKGLKSFYN 428 >4MKS-A nrPDB Length = 440 Score = 631 bits (1628), Expect = 0.0, Method: Composition-based stats. Identities = 228/435 (52%), Positives = 300/435 (68%), Gaps = 16/435 (3%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGK 60 I I ARE+LDSRGNPT E ++YT G F RA VPSGASTG +EA+ELRDGDK R+ G+ Sbjct: 3 VITDIHAREVLDSRGNPTAEAEVYTELGGFGRAIVPSGASTGEHEAVELRDGDKSRFGGQ 62 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 GVL AV+++N IA A+I GL V +Q +D M++LDGT NK + GANAIL VSLA + Sbjct: 63 GVLTAVENVNGEIAKAVI--GLDVTDQRLIDQTMIDLDGTPNKGRLGANAILSVSLASAR 120 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A A E LPLY + L G + +LP P NVINGG HA N + +QEFMI+PVGA+S + Sbjct: 121 AAADELGLPLYEY---LGGPNAHVLPTPMMNVINGGKHADNNVDIQEFMIMPVGAKSLHE 177 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--E 238 A+R+GAE +HTLKG+++++ ++T VGDEGGFAPN+ N E E++ EAI +AGY + Sbjct: 178 AVRMGAETFHTLKGLLQER--GESTAVGDEGGFAPNLKNNEEPFEILVEAIQRAGYKPGQ 235 Query: 239 KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I I D AASEFY D R T ++ +L +D V YPV+S+EDP D+ Sbjct: 236 DIAIAFDCAASEFYNK---DTKKYVTVADGREYTAEEWTSLIEDLVDKYPVISVEDPLDE 292 Query: 299 DDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 +DW W FT +G +QIVGDDL VTN +E+ ++ N +L+K+NQIG++TE +A Sbjct: 293 NDWEGWKTFTERLGDKVQIVGDDLFVTNTSYLEKGIKMGVANSILIKLNQIGTLTETFEA 352 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 ++A+E G+ +VSHRSGETEDT IADLVV GQIKTG+ R++R+AKYNQLMRIEE Sbjct: 353 IEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEEA 412 Query: 417 LGDEARFAG-HNFRN 430 LG A++ G H+F N Sbjct: 413 LGSTAQYKGIHSFYN 427 >3ZLH-A nrPDB Length = 455 Score = 629 bits (1624), Expect = 0.0, Method: Composition-based stats. Identities = 213/437 (48%), Positives = 297/437 (67%), Gaps = 17/437 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPT+EV++YT G F R VPSGASTG +EA+ELRDGDK RYLG G Sbjct: 24 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLG 83 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 KAVD++N+ IA A+I G V +Q+ +D M+ LDGT NK K GANAILGVS+AV +A Sbjct: 84 TQKAVDNVNNIIAKAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARA 141 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A E+PLY + L G + +LP P N+INGGSH+ +A QEFMI+PVGA +F++ Sbjct: 142 AADYLEVPLYTY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEG 198 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT---E 238 +R GAEV+H LK ++K++ T VGDEGGFAP + +E + +AI+ AGY Sbjct: 199 LRWGAEVFHALKKILKER--GLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGEN 256 Query: 239 KIVIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPF 296 I+IG D A+SEFY + YD + + +Q+ ++ V YP+++IED Sbjct: 257 GIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV-DYLEELVNKYPIITIEDGM 315 Query: 297 DQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAI 354 D++DW W T +G +Q+VGDD VTN + + R ++E A N +L+KVNQIG++TE Sbjct: 316 DENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETF 375 Query: 355 QACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIE 414 +A ++A+E G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RIE Sbjct: 376 EAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIE 435 Query: 415 EELGDEARFAG-HNFRN 430 ++LG+ A++ G +F N Sbjct: 436 DQLGEVAQYKGIKSFYN 452 >1W6T-A nrPDB Length = 444 Score = 628 bits (1619), Expect = e-180, Method: Composition-based stats. Identities = 211/436 (48%), Positives = 292/436 (66%), Gaps = 16/436 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLF-RAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I ++ARE+LDSRGNPT+EV++YT G F R VPSGASTG +EA+ELRDGDK RY G G Sbjct: 14 ITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLG 73 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 KAVD++N+ IA A+I G V +Q+ +D M+ LDGT NK K GANAILGVS+AV +A Sbjct: 74 TQKAVDNVNNIIAEAII--GYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARA 131 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A E+PLY + L G + +LP P N+INGGSH+ +A QEFMILPVGA +F++A Sbjct: 132 AADYLEIPLYSY---LGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEA 188 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R GAE++H LK ++K + T VGDEGGFAP + +E + AI+ AGY + Sbjct: 189 LRYGAEIFHALKKILKSR--GLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKD 246 Query: 240 IVIGMDVAASEFYRDGK--YDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFD 297 + +G D A+SEFY + YD + + +Q ++ V YP+++IED D Sbjct: 247 VFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQ-IDYLEELVNKYPIITIEDGMD 305 Query: 298 QDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQ 355 ++DW W T +G +Q+VGDD VTN + R ++E A N +L+KVNQIG++TE + Sbjct: 306 ENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFE 365 Query: 356 ACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A ++A+E G+ +VSHRSGETED+ IAD+ V GQIKTG+ R++R+AKYNQL+RIE+ Sbjct: 366 AIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIED 425 Query: 416 ELGDEARFAG-HNFRN 430 +LG+ A + G +F N Sbjct: 426 QLGEVAEYRGLKSFYN 441 >2PA6-A nrPDB Length = 427 Score = 610 bits (1573), Expect = e-175, Method: Composition-based stats. Identities = 244/432 (56%), Positives = 319/432 (73%), Gaps = 15/432 (3%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAK-GLFRAAVPSGASTGIYEALELRDGDKQRYLG 59 I+ I ARE++DSRGNPTVEV++ T G A VPSGASTG +EALELRD +K R+ G Sbjct: 9 FEIKDIVAREVIDSRGNPTVEVEVITKGNGYGSAIVPSGASTGTHEALELRDKEK-RFGG 67 Query: 60 KGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVC 119 KGVL AV+++NS I P ++ G Q ++D +M+ELDGT NKS+ GANAIL VSLAV Sbjct: 68 KGVLMAVENVNSIIRPEIL--GYDARMQREIDTIMIELDGTPNKSRLGANAILAVSLAVA 125 Query: 120 KAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 KA AA ++PLY++ L G + ++PVP NVINGG HAGN L +QEFMI+PVGA S Sbjct: 126 KAAAATAKIPLYKY---LGGFNSYVMPVPMMNVINGGKHAGNDLDLQEFMIMPVGATSIS 182 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEK 239 +A+R+G+EVYH LK VI +KYGK+A NVGDEGGFAP + + EAL+L+ E++ KAGY ++ Sbjct: 183 EAVRMGSEVYHVLKNVILEKYGKNAVNVGDEGGFAPPLKTSREALDLLTESVKKAGYEDE 242 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 +V +D AASEFY+DG Y ++ K +T ++L Y+ V +YP+VSIEDPF ++ Sbjct: 243 VVFALDAAASEFYKDGYYYVEGK-------KLTREELLDYYKALVDEYPIVSIEDPFHEE 295 Query: 300 DWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 D+ ++ T + IQIVGDDL VTN +R+ + +E KA N LLLKVNQIG+++EA+ A +L Sbjct: 296 DFEGFAMITKELDIQIVGDDLFVTNVERLRKGIEMKAANALLLKVNQIGTLSEAVDAAQL 355 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGD 419 A NG+GV+VSHRSGETEDT IADL V L +GQIKTGAP R ER AKYNQL+RIE+ELG Sbjct: 356 AFRNGYGVVVSHRSGETEDTTIADLSVALNSGQIKTGAPARGERTAKYNQLIRIEQELG- 414 Query: 420 EARFAGHNFRNP 431 +++AG NFR P Sbjct: 415 LSKYAGRNFRCP 426 >4Z1Y-A nrPDB Length = 426 Score = 608 bits (1568), Expect = e-174, Method: Composition-based stats. Identities = 241/430 (56%), Positives = 302/430 (70%), Gaps = 17/430 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKG-LFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 IE I ARE+LDSRGNPT+EVD+ G + RA VPSGASTG +EALELRDGDK RY GKG Sbjct: 5 IEAIVAREVLDSRGNPTIEVDVRLESGDVGRAIVPSGASTGAHEALELRDGDKSRYNGKG 64 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 VLKAV +N IA ALI G +Q LD ++ LDGT NKSK GANAILGVSLA KA Sbjct: 65 VLKAVQAVNEDIAEALI--GFDAADQIALDQELIALDGTPNKSKLGANAILGVSLAAAKA 122 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 AA LPLYR+ L G +LPVP N++NGG HA N QEFMI+PVGAESFR+ Sbjct: 123 AAAAFGLPLYRY---LGGVYAHVLPVPMMNIMNGGQHATNSTDFQEFMIMPVGAESFREG 179 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R GAE+YH LK VI D+ +T VGDEGGFAP++ N L+L+ EAI+KAGY E+ Sbjct: 180 LRWGAEIYHMLKKVIHDR--GFSTTVGDEGGFAPSLPTNDAPLQLIMEAIEKAGYRPGEQ 237 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 IVI +D A +E + DGKY L + R ++ ++ + D V YP++S+ED +D Sbjct: 238 IVIALDPATTEIFEDGKYHLKREG-----RSLSSAEMVDYWVDLVNRYPIISLEDGLAED 292 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 DW W+ A +G +Q+VGDD VTN +R++RA+E KA N +L+K+NQIGS+TE + A Sbjct: 293 DWEGWALLRAKLGDRVQLVGDDFLVTNVQRLQRAIEAKAANSILIKLNQIGSLTETLSAI 352 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 +LAQ +GW +VSHRSGE+ED IADLVV GQIKTGAP R++R+AKYNQL+RIEEEL Sbjct: 353 QLAQRSGWTAVVSHRSGESEDVTIADLVVATNAGQIKTGAPARTDRIAKYNQLLRIEEEL 412 Query: 418 GDEARFAGHN 427 G AR+AG + Sbjct: 413 GSAARYAGRS 422 >5J04-A nrPDB Length = 425 Score = 596 bits (1538), Expect = e-171, Method: Composition-based stats. Identities = 228/428 (53%), Positives = 287/428 (67%), Gaps = 20/428 (4%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFR-AAVPSGASTGIYEALELRDGDKQRYLGKG 61 I +I AREILDSRG PTVE +++ G A VPSGASTG +EA ELRD D RY GKG Sbjct: 5 IAEITAREILDSRGRPTVEAEVHLEDGSVGLAQVPSGASTGTFEAHELRDDDPSRYGGKG 64 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV+++ S I ALI GLS ++QE LD M+ LDGT NK GANAIL VSLA A Sbjct: 65 VQKAVENV-SAIEDALI--GLSALDQEGLDKAMIALDGTPNKKNLGANAILAVSLATAHA 121 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDA 181 A LPLYR+ L G +LPVP NVINGG+HA N + QEFMI+PVGA SF++A Sbjct: 122 AATSLNLPLYRY---LGGPLANVLPVPMMNVINGGAHADNNVDFQEFMIMPVGAPSFKEA 178 Query: 182 MRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EK 239 +R GAEV+H L V+KDK AT VGDEGGFAPN+ N EALEL+ AI+ AGY E+ Sbjct: 179 LRWGAEVFHALAKVLKDK--GLATGVGDEGGFAPNLGSNKEALELLLTAIEAAGYKPGEQ 236 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 + + MDVA+SEFY++G Y D S + + D V YP+VSIED +D Sbjct: 237 VALAMDVASSEFYKNGLYTCDGVSHEPAG-------MIGILADLVSQYPIVSIEDGLQED 289 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 DW+ W T +G +Q+VGDDL VTNP R++ +E+ N +L+K+NQIG++TE ++ Sbjct: 290 DWSNWKTLTQQLGSTVQLVGDDLFVTNPDRLQSGIEQGVGNAVLIKLNQIGTLTETLRTI 349 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEEL 417 LA +G+ ++SHRSGETEDT IADL V GQIKTG+ RSER+AKYN+L+RIE L Sbjct: 350 DLATRSGYRSVISHRSGETEDTTIADLAVATRAGQIKTGSLSRSERIAKYNRLLRIEAAL 409 Query: 418 GDEARFAG 425 G+ A +AG Sbjct: 410 GENALYAG 417 >6NB2-A nrPDB Length = 430 Score = 596 bits (1537), Expect = e-171, Method: Composition-based stats. Identities = 218/428 (50%), Positives = 284/428 (66%), Gaps = 19/428 (4%) Query: 5 KIWAREILDSRGNPTVEVDLYTAKGL-FRAAVPSGASTGIYEALELRDGDKQRYLGKGVL 63 KI AREILDSRGNPT+E D+ G+ RA+VPSGASTG EA ELRD D +RY GKGV Sbjct: 13 KIQAREILDSRGNPTIEADVTLTTGIIGRASVPSGASTGSREACELRDNDPKRYAGKGVQ 72 Query: 64 KAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGA 123 KAV H+N+ I AL GLSV +QE LD ++ +LD TENKS GANAIL SLA +A A Sbjct: 73 KAVKHVNNEINQAL--QGLSVEDQENLDRILCQLDNTENKSHLGANAILATSLACARARA 130 Query: 124 AERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMR 183 PLY L + +PVP N++NGG+HA N + +QEFMI+P+GA F A++ Sbjct: 131 LSLNQPLYM---TLNQGDMMTMPVPMMNILNGGAHADNNVDIQEFMIMPIGAPDFPVALQ 187 Query: 184 LGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--EKIV 241 +G E++H LK V+K + T VGDEGGFAPNI N +AL+L+ EAI+KAG+ E IV Sbjct: 188 MGTEIFHVLKSVLKKQ--GLNTAVGDEGGFAPNIQSNRQALDLLSEAIEKAGFRLGEDIV 245 Query: 242 IGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 +DVAASE + +G Y + ++ QL Y + + YP+VSIED D+ DW Sbjct: 246 FALDVAASELFNEGFYHM-----YSENQKFDSHQLIEYYANLISSYPIVSIEDGLDEKDW 300 Query: 302 AAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKL 359 + W + T ++G +Q+VGDDL VTNPK + + + N +L+KVNQIG+++E QA KL Sbjct: 301 SGWKQLTTHLGNKVQLVGDDLFVTNPKILREGIAQGIANAILIKVNQIGTLSETRQAIKL 360 Query: 360 AQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGD 419 A +NG+ ++SHRSGETEDTFIADL V GQIKTG+ CR++R AKYNQL+RI E Sbjct: 361 AYDNGYRCVMSHRSGETEDTFIADLAVASGCGQIKTGSLCRTDRTAKYNQLLRINEL--A 418 Query: 420 EARFAGHN 427 +AG N Sbjct: 419 SLPYAGKN 426 >3TQP-A nrPDB Length = 428 Score = 587 bits (1513), Expect = e-168, Method: Composition-based stats. Identities = 209/430 (48%), Positives = 290/430 (67%), Gaps = 18/430 (4%) Query: 2 SIEKIWAREILDSRGNPTVEVDLYTAKGLFR-AAVPSGASTGIYEALELRDGDKQRYLGK 60 +I I A EILDSR NPT+EV + + + AAVPSGASTG EA+ELRD D +RY GK Sbjct: 4 TITDINAHEILDSRANPTLEVRVTLSSQAYGCAAVPSGASTGEREAVELRDNDLERYGGK 63 Query: 61 GVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCK 120 GVL+AV+++N I AL+ G QE++D +M+ELDGTENK+ GANAILGVSLAV Sbjct: 64 GVLQAVENVNGPIRDALL--GQDPRSQEEIDRIMIELDGTENKANLGANAILGVSLAVAY 121 Query: 121 AGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 A A +LPLYR++ G +PVP N+INGG+HA N L QEFMI+PVGA +F + Sbjct: 122 AAANNADLPLYRYLGGDGG--PFSMPVPMMNIINGGAHATNNLDFQEFMIVPVGAPTFAE 179 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--E 238 A+R GAEV+H LK + + + VGDEGGFAP++ N A EL+ EAI+ A Y + Sbjct: 180 ALRYGAEVFHALKKRLVSR--GLMSAVGDEGGFAPDLPNNEAAFELILEAIEDANYVPGK 237 Query: 239 KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I + +D A+SE Y++G+YD + + +T +++ ++ + YPV+SIED + Sbjct: 238 DIYLALDAASSELYQNGRYDFE-------NNQLTSEEMIDRLTEWTKKYPVISIEDGLSE 290 Query: 299 DDWAAWSKFTANV--GIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 +DWA W T + +Q+VGDD+ VTNP +E+ +++ N +L+K+NQIG++TE + Sbjct: 291 NDWAGWKLLTERLENKVQLVGDDIFVTNPDILEKGIKKNIANAILVKLNQIGTLTETLAT 350 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 LA+ N +GV++SHRSGETEDT IADL V QIKTG+ CRS+R+AKYN+L++IE E Sbjct: 351 VGLAKSNKYGVIISHRSGETEDTTIADLAVATDARQIKTGSLCRSDRVAKYNRLLQIERE 410 Query: 417 LGDEARFAGH 426 L D+A +AG Sbjct: 411 LNDQAPYAGK 420 >6BFZ-A nrPDB Length = 449 Score = 584 bits (1506), Expect = e-167, Method: Composition-based stats. Identities = 226/431 (52%), Positives = 298/431 (69%), Gaps = 14/431 (3%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKG-LFRAAVPSGASTGIYEALELRDGDKQRYLGKG 61 I KI REI+DSRGNPTVE +++ G + AA PSGASTG EALELRDGDK R+LGKG Sbjct: 21 IVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKG 80 Query: 62 VLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 V KAV +N IA ALI G +Q +D +M++LDGTENKSKFGANAIL VSLA KA Sbjct: 81 VTKAVAAVNGPIAQALI--GKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKA 138 Query: 122 GAAERELPLYRHIAQLAGNS-DLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRD 180 AA + +PLY HIA+L G +PVP N+INGG HA N + +QEFMI PVGA++ ++ Sbjct: 139 AAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKE 198 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT--E 238 A+R+G+EV+H L V+K K T VGDEGG+APN+ N+EAL ++ EA+ AGY + Sbjct: 199 AIRMGSEVFHHLAKVLKAK--GMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGK 256 Query: 239 KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 I + MD AASEFY+DGKY L + ++ T ++ ++ + YP+VSIED D+ Sbjct: 257 DITLAMDCAASEFYKDGKYVLAG----EGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDE 312 Query: 299 DDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQA 356 DW ++ T +G IQ+VGDDL VTN K ++ +E+ N +L+K NQIGS+TE + A Sbjct: 313 SDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAA 372 Query: 357 CKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 K+A++ G+ ++SHRSGETED IADL VG GQIKTG+ RS+R+AKYNQL+RIEE Sbjct: 373 IKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEA 432 Query: 417 LGDEARFAGHN 427 LG++A + G Sbjct: 433 LGEKAPYNGRK 443 >3UJ2-A nrPDB Length = 449 Score = 583 bits (1503), Expect = e-167, Method: Composition-based stats. Identities = 225/432 (52%), Positives = 299/432 (69%), Gaps = 19/432 (4%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGL-FRAAVPSGASTGIYEALELRDGDKQRYLG 59 + IEK+ REI+DSRGNPTVE ++Y A G+ R PSGASTG +EALELRDGDK R+ G Sbjct: 26 LEIEKVIGREIIDSRGNPTVEAEVYLAGGVTGRGTAPSGASTGEFEALELRDGDKGRFGG 85 Query: 60 KGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVC 119 KGV KAV +IN+ I+ I SG+ + +D M++ DGT++KSKFGANA+L VS+A Sbjct: 86 KGVTKAVQNINTEISE--ILSGMDASDIYAVDRAMIDADGTKDKSKFGANAVLAVSIACA 143 Query: 120 KAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 KA AA +PLYR + L N LPVP N++NGG+HA N + +QEFMI+PVGAESFR Sbjct: 144 KAAAAALGVPLYRFLGGLNANR---LPVPMMNILNGGAHAANTVDVQEFMIMPVGAESFR 200 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT-- 237 +A+R EV+H L G++K K AT+VGDEGGFAP++ + EA+E + EA+ AGY Sbjct: 201 EALRQCTEVFHALAGLLKSK--GLATSVGDEGGFAPDLASDEEAIEYILEAVKLAGYEPG 258 Query: 238 EKIVIGMDVAASEFY--RDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDP 295 V+ MD A+SE+ + G+Y L R ++L A ++ YP+VSIED Sbjct: 259 RDFVLAMDAASSEWKGEKKGEYIL-----PKCKRKFASEELVAHWKSLCERYPIVSIEDG 313 Query: 296 FDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEA 353 D++DW W T +G IQ+VGDDL VTN +R+ + ++E+ N +L+K+NQIG+V+E Sbjct: 314 LDEEDWEGWQYMTRELGDKIQLVGDDLFVTNTERLNKGIKERCGNSILIKLNQIGTVSET 373 Query: 354 IQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRI 413 ++A K+A + G+ +VSHRSGETEDT IADL V L TGQIKTGAP RSER+AKYNQL+RI Sbjct: 374 LEAIKMAHKAGYTAVVSHRSGETEDTTIADLAVALNTGQIKTGAPSRSERVAKYNQLLRI 433 Query: 414 EEELGDEARFAG 425 EEELGD A + G Sbjct: 434 EEELGDSAVYPG 445 >6O4N-A nrPDB Length = 432 Score = 573 bits (1477), Expect = e-164, Method: Composition-based stats. Identities = 213/432 (49%), Positives = 278/432 (64%), Gaps = 21/432 (4%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFR-AAVPSGASTGIYEALELRDGDKQRYLG 59 + I I AREILDSRG PT+ V + T G F A VPSGASTGI EALELRD D +RY G Sbjct: 12 VVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQG 71 Query: 60 KGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVC 119 KGVL+A+ ++ + PAL G SV +Q D +M++ DGT NK K GANAILGVSLA+ Sbjct: 72 KGVLQAISNVEKVLVPAL--QGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALA 129 Query: 120 KAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 KA A + PLYR+ L G+ +LP P N+INGG HA N L QEFMI P+ A S + Sbjct: 130 KAAANTLQRPLYRY---LGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLK 186 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYT-- 237 +A+R+GAEV++ LK +++++ + AT VGDEGGFAPN+ N+EAL+L+ AI+ AG+T Sbjct: 187 EAVRMGAEVFNALKKILQNR--QLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPR 244 Query: 238 EKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFD 297 E I + +D AAS FY D KS D + + YP+ SIED Sbjct: 245 EDISLALDCAASSFYNTQDKTYDGKSYADQ---------VGILAELCEHYPIDSIEDGLA 295 Query: 298 QDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQ 355 ++D+ W + +G +Q+VGDDL VTN I + + N +L+K NQIG++TE + Sbjct: 296 EEDFEGWKLLSETLGDRVQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAE 355 Query: 356 ACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEE 415 A +LA G+ ++SHRSGETEDT IADL V TGQIKTG+ RSER+AKYN+LM IEE Sbjct: 356 AIRLATIQGYATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEE 415 Query: 416 ELGDEARFAGHN 427 E+G EA F N Sbjct: 416 EMGPEALFQDSN 427 >6J36-A nrPDB Length = 460 Score = 559 bits (1440), Expect = e-159, Method: Composition-based stats. Identities = 209/453 (46%), Positives = 287/453 (63%), Gaps = 32/453 (7%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFR-AAVPSGASTGIYEALELRDGDKQR----Y 57 I K++AREILDSRGNPT++VD+YT G F A VPSGASTG EALELRD + + Y Sbjct: 4 ITKVFAREILDSRGNPTIQVDVYTLAGGFGSAIVPSGASTGSREALELRDTNTKYADNWY 63 Query: 58 LGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLA 117 KGV+ AVD++N+ IAP +I GL Q +D ++ELDGT NK K GANAILGVSLA Sbjct: 64 GQKGVMTAVDNVNNIIAPEII--GLCCKNQRLIDQKIIELDGTPNKEKLGANAILGVSLA 121 Query: 118 VCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAES 177 V KA A E +PL+R+ L G + ++PVP NVINGG HA N L QEFMI+P+G + Sbjct: 122 VAKAAANELRMPLFRY---LGGTNPTLMPVPMLNVINGGEHASNTLDFQEFMIMPLGFRT 178 Query: 178 FRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGY- 236 F++A++ +V+H L ++K T VGDEGGFAPN + +AL+ + +AI ++G+ Sbjct: 179 FKEALQAANKVFHNLAKLLKKS--GFETQVGDEGGFAPNFNSHEQALDFLVDAIKESGFN 236 Query: 237 -----TEKIVIGMDVAASEFYRDGKYDLDF---------KSPTDPSRYITGDQLGALYQD 282 + I +D AASEFY KY ++ D ++L Y Sbjct: 237 PGFKGENAVAIAIDAAASEFYNGQKYVFKKLKAASLSKNQADLDEKFEFNSEELLNYYGQ 296 Query: 283 FVRDYPVVSIEDPFDQDDWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCL 340 + YP++SIED F + DW + F G QIVGDDLTVTN + +++A+ KA N + Sbjct: 297 LLAKYPIISIEDGFAESDWQGFIAFNQKYGNNHQIVGDDLTVTNVEILKKAINLKAINSI 356 Query: 341 LLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCR 400 L+K+NQIG+++E + A LAQ++G ++SHRSGE+EDT IADL V + +GQIKTG+ R Sbjct: 357 LIKLNQIGTLSETLDAIHLAQKSGMTAVISHRSGESEDTTIADLAVAVSSGQIKTGSLSR 416 Query: 401 SERLAKYNQLMRIEEELGDEAR--FAGHN-FRN 430 ++R+AKYN+L+ IEE L A+ + G F N Sbjct: 417 TDRIAKYNRLLVIEEYLNSYAKADYIGREVFYN 449 >3QN3-A nrPDB Length = 417 Score = 558 bits (1438), Expect = e-159, Method: Composition-based stats. Identities = 201/419 (47%), Positives = 275/419 (65%), Gaps = 18/419 (4%) Query: 1 MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAA-VPSGASTGIYEALELRDGDKQRYLG 59 + IE + A E+LDSRGNPTV+ ++ + G AA VPSGASTG EALELRD D +R+ G Sbjct: 5 LVIEDVRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDND-ERFGG 63 Query: 60 KGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVC 119 KGVLKAV ++N TIA ++ GL Q +LD+ + ELDGT N S GANA LGVS+A Sbjct: 64 KGVLKAVANVNETIADEIL--GLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATA 121 Query: 120 KAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFR 179 +A AA +PLYR+ L G + ILPVP N+INGG+HA N + QEFMI+P G SF+ Sbjct: 122 RAAAAALGMPLYRY---LGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFK 178 Query: 180 DAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEK 239 +A+R E+Y LK + + +T +GDEGGFAPN+ N+E ++L+ I KAGY + Sbjct: 179 EALRSVCEIYAILKKELANS--GHSTALGDEGGFAPNLANNTEPIDLLMTCIKKAGYENR 236 Query: 240 IVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQD 299 + I +DVA++EF++DGKY ++ K+ + + L Y + YP+ SIED ++ Sbjct: 237 VKIALDVASTEFFKDGKYHMEGKA-------FSSEALIERYVELCAKYPICSIEDGLAEN 289 Query: 300 DWAAWSKFTANVG--IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQAC 357 D+ W K T +G IQ+VGDDL VTN + + +K N +L+K NQIG++T+ ++ Sbjct: 290 DFEGWIKLTEKLGNKIQLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTV 349 Query: 358 KLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEE 416 +LAQ N + ++SHRSGE+ED FIAD V L TGQIKTGA R ER AKYN+L+ IE E Sbjct: 350 RLAQRNNYKCVMSHRSGESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIEFE 408 >3R11-A nrPDB Length = 379 Score = 98.0 bits (243), Expect = 6e-21, Method: Composition-based stats. Identities = 48/206 (23%), Positives = 84/206 (40%), Gaps = 21/206 (10%) Query: 178 FRDAMRLGAEV-YHTL---------KGVIKDKYGKDATNVGDE-GGFAPNILENSEALEL 226 F A ++ ++ YH L ++ K T+V G A I +E Sbjct: 97 FNSAAKMAIDLAYHDLLAKEQDISVAKLLGAKANSIVTDVSISCGNVAETIQNIQNGVEA 156 Query: 227 VKEAID---KAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDF 283 AI A + I + + +EF ++ K+ D + ++ Q + Sbjct: 157 NFTAIKVKTGADFNRDIQL-LKALDNEFSKNIKFRFDANQGWNLAQ---TKQFIEEINKY 212 Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLK 343 + + IE P D A ++ T I +V D+ +V + K ER ++E+ACN + +K Sbjct: 213 SLNVEI--IEQPVKYYDIKAMAEITKFSNIPVVADE-SVFDAKDAERVIDEQACNMINIK 269 Query: 344 VNQIGSVTEAIQACKLAQENGWGVMV 369 + + G + EA + KLA G MV Sbjct: 270 LAKTGGILEAQKIKKLADSAGISCMV 295 >3IK4-A nrPDB Length = 365 Score = 85.7 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 288 PVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347 P+V E P ++DWA ++ TA G + D+ + + + R E + + +K+ + Sbjct: 216 PMVLFEQPLPREDWAGMAQVTAQSGFAVAADE-SARSAHDVLRIAREGTASVINIKLMKA 274 Query: 348 GSVTEAIQACKLAQENGWGVMV 369 G V E ++ +AQ G G+M+ Sbjct: 275 G-VAEGLKMIAIAQAAGLGLMI 295 >3JW7-A nrPDB Length = 354 Score = 66.8 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 49/118 (41%), Gaps = 2/118 (1%) Query: 259 LDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGD 318 D K D ++ T Q DY + +E P + D T+ V I+ D Sbjct: 182 FDIKLRLDANQAWTPKDAVKAIQAL-ADYQIELVEQPVKRRDLEGLKYVTSQVNTTIMAD 240 Query: 319 DLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGET 376 + + + + V++ + + +K+ + G + EA++ ++ + G M+ + ET Sbjct: 241 E-SCFDAQDALELVKKGTVDVINIKLMKCGGIHEALKINQICETAGIECMIGCMAEET 297 >3QLD-A nrPDB Length = 388 Score = 58.7 bits (141), Expect = 4e-09, Method: Composition-based stats. Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 11/155 (7%) Query: 221 SEALELVKEAIDKA---GYTE---KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGD 274 SE+L+++ +++D A G+ KI G D AA + R DL + + S Sbjct: 147 SESLDVLIQSVDAAVEQGFRRVKLKIAPGRDRAAIKAVRLRYPDLAIAADANGSYR---P 203 Query: 275 QLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEE 334 + + + Y + IE P +DDW +K A++ + D+ +V + + ++ Sbjct: 204 EDAPVLRQL-DAYDLQFIEQPLPEDDWFDLAKLQASLRTPVCLDE-SVRSVRELKLTARL 261 Query: 335 KACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMV 369 A L +K ++G ++A +A E G V Sbjct: 262 GAARVLNVKPGRLGGFGATLRALDVAGEAGMAAWV 296 >3S5S-A nrPDB Length = 389 Score = 58.3 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 2/81 (2%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 V +E P +DDW + T G+ V D + + + + R E+A + +K+ + G Sbjct: 218 VALLEQPVPRDDWDGMKEVTRRAGVD-VAADESAASAEDVLRVAAERAATVVNIKLMK-G 275 Query: 349 SVTEAIQACKLAQENGWGVMV 369 + EA+ +A+ G G+M+ Sbjct: 276 GIAEALDIAAVARAAGLGLMI 296 >1TKK-A nrPDB Length = 366 Score = 57.2 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 + +E P +DD A K T I+ D+ +V P++ ++ ++ + + +K+ + G Sbjct: 215 IELVEQPVHKDDLAGLKKVTDATDTPIMADE-SVFTPRQAFEVLQTRSADLINIKLMKAG 273 Query: 349 SVTEAIQACKLAQENGWGVMV 369 ++ A + +A+ G MV Sbjct: 274 GISGAEKINAMAEACGVECMV 294 >1WUE-A nrPDB Length = 386 Score = 54.9 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLK 343 + Y + IE PF DD+ ++ + +I D+ + + K + A+ +C + LK Sbjct: 224 LDHYQLAMIEQPFAADDFLDHAQLQRELKTRICLDE-NIRSLKDCQVALALGSCRSINLK 282 Query: 344 VNQIGSVTEAIQACKLAQEN 363 + ++G + EA++ QEN Sbjct: 283 IPRVGGIHEALKIAAFCQEN 302 >2ZC8-A nrPDB Length = 369 Score = 53.3 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 62/165 (37%), Gaps = 12/165 (7%) Query: 204 ATNVGDEGGFAPNILENSEALELVKEAIDKAGYTE---KIVIGMDVAASEFYRDGKYDLD 260 A VG G P++ + +E E GY KI G D + R+ + Sbjct: 129 AVEVGVSLGIQPSVEDTLRVVERHLE----EGYRRIKLKIKPGWDYEVLKAVREAFPEAT 184 Query: 261 FKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDL 320 + + + + + DY IE P DD +K + I D+ Sbjct: 185 LTADANSAYSLANLAQLKRLDELRLDY----IEQPLAYDDLLDHAKLQRELSTPICLDE- 239 Query: 321 TVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGW 365 ++T ++ +A+E A +K ++G E+++ LA+ G Sbjct: 240 SLTGAEKARKAIELGAGRVFNVKPARLGGHGESLRVHALAESAGI 284 >3U9I-A nrPDB Length = 393 Score = 53.0 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 2/79 (2%) Query: 291 SIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSV 350 E P +DD + TA + + D+ +V + R A + L +K+ + G + Sbjct: 249 LFEQPVAKDDEEGLRRLTATRRVPVAADE-SVASATDAARLARNAAVDVLNIKLMKCG-I 306 Query: 351 TEAIQACKLAQENGWGVMV 369 EA+ +A+ G +M+ Sbjct: 307 VEALDIAAIARTAGLHLMI 325 >2GGG-A nrPDB Length = 375 Score = 53.0 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 18/163 (11%) Query: 210 EGGFAPNILENSEA-LELVKEAIDKAGYTE---KIVIGMDV----AASEFYRDGKYDLDF 261 E G + I + +A ++LV+ +++ GY KI G DV A E + D + +D Sbjct: 138 EVGVSLGIQADEQATVDLVRRHVEQ-GYRRIKLKIKPGWDVQPVRATREAFPDIRLTVDA 196 Query: 262 KSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLT 321 S + QL Y + IE P DD ++ + + D+ + Sbjct: 197 NSAYTLADAGRLRQLDE--------YDLTYIEQPLAWDDLVDHAELARRIRTPLCLDE-S 247 Query: 322 VTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENG 364 V + +A+ A + LKV ++G E+ + +AQ G Sbjct: 248 VASASDARKALALGAGGVINLKVARVGGHAESRRVHDVAQSFG 290 >2QDE-A nrPDB Length = 397 Score = 52.6 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 68/195 (34%), Gaps = 20/195 (10%) Query: 183 RLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAID----KAGYTE 238 R G VY L G ++ G EAL +++E KAG Sbjct: 118 RFGVPVYQLLGGKTIERIPLGLVL-----GAGEPEAVAEEALAVLREGFHFVKLKAGGPL 172 Query: 239 KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 K I M +E R D+D + + + L + + Y + IE P Sbjct: 173 KADIAM---VAEVRRAVGDDVDLFIDINGA-WTYDQALTTIRA--LEKYNLSKIEQPLPA 226 Query: 299 DDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 D ++ V I D+ + + + + A + L++K + G + +A + Sbjct: 227 WDLDGMARLRGKVATPIYADE-SAQELHDLLAIINKGAADGLMIKTQKAGGLLKAQRWLT 285 Query: 359 LAQENGW----GVMV 369 LA+ G MV Sbjct: 286 LARLANLPVICGCMV 300 >3MY9-A nrPDB Length = 377 Score = 50.6 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 32/74 (43%), Gaps = 1/74 (1%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE P + A + F A + I+ D+ + + + V +A + + +K+ + G + Sbjct: 222 IEQPVPRRHLDAMAGFAAALDTPILADE-SCFDAVDLMEVVRRQAADAISVKIMKCGGLM 280 Query: 352 EAIQACKLAQENGW 365 +A +A G Sbjct: 281 KAQSLMAIADTAGL 294 >3I6E-A nrPDB Length = 385 Score = 50.3 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE P + ++ + ++ D+ +V P+ + RA E C+ + +K+ + G +T Sbjct: 223 IEQPVRAHHFELMARLRGLTDVPLLADE-SVYGPEDMVRAAHEGICDGVSIKIMKSGGLT 281 Query: 352 EAIQACKLAQENGW 365 A ++A +G Sbjct: 282 RAQTVARIAAAHGL 295 >3I4K-A nrPDB Length = 383 Score = 50.3 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 36/89 (40%), Gaps = 1/89 (1%) Query: 279 LYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACN 338 Y + + V E P DD + T + ++ D+ +V P V+ +A + Sbjct: 212 HYLPILAEAGVELFEQPTPADDLETLREITRRTNVSVMADE-SVWTPAEALAVVKAQAAD 270 Query: 339 CLLLKVNQIGSVTEAIQACKLAQENGWGV 367 + LK + G + E+ + +A+ G Sbjct: 271 VIALKTTKHGGLLESKKIAAIAEAGGLAC 299 >3DFY-A nrPDB Length = 345 Score = 48.7 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 + E P ++D + + D+ + + R V+E+A + + +K+ + G Sbjct: 212 IAVYEQPVRREDIEGLKFVRFHSPFPVAADE-SARTKFDVMRLVKEEAVDYVNIKLMKSG 270 Query: 349 SVTEAIQACKLAQENGWGVMV 369 +++A+ ++A+ +G +M+ Sbjct: 271 -ISDALAIVEIAESSGLKLMI 290 >3IJQ-A nrPDB Length = 338 Score = 48.3 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 50/132 (37%), Gaps = 6/132 (4%) Query: 239 KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQ 298 K+ +G D E + D D ++ Q ++++ +V IE P + Sbjct: 153 KVKLGRD-NDKEMIETIRSVTDLPIAVDANQGWKDRQYALDMIHWLKEKGIVMIEQPMPK 211 Query: 299 DDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVE-EKACNCLLLKVNQIGSVTEAIQAC 357 + + T + + D+ + +R+ + A + +K+ + + EA + Sbjct: 212 EQLDDIAWVTQQSPLPVFADE----SLQRLGDVAALKGAFTGINIKLMKCTGMREAWKMV 267 Query: 358 KLAQENGWGVMV 369 LA G VMV Sbjct: 268 TLAHALGMRVMV 279 >2P8B-A nrPDB Length = 369 Score = 47.9 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 + IE P DD A + + + ++ D+ + + + + ++ +A + + +K+ + G Sbjct: 214 IDWIEQPVIADDIDAMAHIRSKTDLPLMIDEGL-KSSREMRQIIKLEAADKVNIKLMKCG 272 Query: 349 SVTEAIQACKLAQENGWGVMV 369 + A++ A+ G V Sbjct: 273 GIYPAVKLAHQAEMAGIECQV 293 >4MMW-A nrPDB Length = 405 Score = 47.9 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 37/78 (47%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE+P D+ +++ + N+ I +VG + ++ AC+ L VN +G +T Sbjct: 254 IEEPMDEQSLSSYKWLSDNLDIPVVGPESAAGKHWHRAEWIKAGACDILRTGVNDVGGIT 313 Query: 352 EAIQACKLAQENGWGVMV 369 A++ LA+ G V Sbjct: 314 PALKTMHLAEAFGMECEV 331 >3Q4D-A nrPDB Length = 368 Score = 47.6 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 47/104 (45%), Gaps = 2/104 (1%) Query: 266 DPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNP 325 D ++ + + + Y + E+P ++ + A K I I+ D+ + N Sbjct: 190 DANQGWSVETAIETLT-LLEPYNIQHCEEPVSRNLYTALPKIRQACRIPIMADE-SCCNS 247 Query: 326 KRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMV 369 ER ++ +AC+ LK+++ +T A+ +LA++ V V Sbjct: 248 FDAERLIQIQACDSFNLKLSKSAGITNALNIIRLAEQAHMPVQV 291 >4HNL-A nrPDB Length = 421 Score = 47.2 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 72/366 (19%), Positives = 123/366 (33%), Gaps = 74/366 (20%) Query: 3 IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGV 62 I + + I R N V V + T KG+ G ST + L Sbjct: 28 ITDVKSFAIKPDRHNLVV-VKVETNKGISGL----GCSTFQFRPL--------------- 67 Query: 63 LKAVDHI-NSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKA 121 AV + + + P L+ G E E + +M ++ NAI G+ +A+ Sbjct: 68 --AVKTVVDEYLRPLLM--GRDANEIEDIWQVM-NVNSYWRNGPITNNAISGIDMALWDI 122 Query: 122 GAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHA-GNKLAMQEFMILPVGAESFRD 180 ++PLY+ L G + +P +HA + L Sbjct: 123 KGQLADMPLYQ---LLGGKARTAIP--------AYTHAVADNLD---------------- 155 Query: 181 AMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKI 240 ++YH + + Y +G GG + E + D+ Y E Sbjct: 156 ------DLYHEIDRFLAAGYRYIRCQLGFYGGNPSQLQTPEEPIS--GSYFDQTDYME-T 206 Query: 241 VIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIED--PFDQ 298 + M A E KY F+ D + +Q + Y + +ED P DQ Sbjct: 207 TLKMFAAIKE-----KYGNQFQMLHDVHERLHPNQAIQ-FAKAAEPYQLFFLEDILPPDQ 260 Query: 299 DDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACK 358 W ++ + I +L NP + V+ + + + V+QIG +T A++ Sbjct: 261 SHW--LTQLRSQSATPIATGELF-NNPMEWQELVKNRQIDFMRAHVSQIGGITPALKLAH 317 Query: 359 LAQENG 364 G Sbjct: 318 FCDAMG 323 >1WUF-A nrPDB Length = 393 Score = 46.0 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 60/153 (39%), Gaps = 4/153 (2%) Query: 212 GFAPNILENSEALELVKEAIDKAGYTE-KIVIGMDVAASEFYRDGKYDLDFKSPTDPSRY 270 G + + +N E L + GY K+ I + +F + S + Sbjct: 153 GVSIGLQQNVETLLQLVNQYVDQGYERVKLKIAPN-KDIQFVEAVRKSFPKLSLMADANS 211 Query: 271 ITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIER 330 + L ++ Y + IE PF D+ + + +I D+ + + K +E+ Sbjct: 212 AYNREDFLLLKEL-DQYDLEMIEQPFGTKDFVDHAWLQKQLKTRICLDE-NIRSVKDVEQ 269 Query: 331 AVEEKACNCLLLKVNQIGSVTEAIQACKLAQEN 363 A +C + LK+ ++G ++ A++ + N Sbjct: 270 AHSIGSCRAINLKLARVGGMSSALKIAEYCALN 302 >1NU5-A nrPDB Length = 370 Score = 45.6 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 274 DQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVE 333 +Q +++ + + V +E P + ++ A + T G+ I+ D+ ++++ Sbjct: 201 EQTASIWIPRLEEAGVELVEQPVPRANFGALRRLTEQNGVAILADE-SLSSLSSAFELAR 259 Query: 334 EKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIA 382 + A + LK+ +G + ++ +A+ G +S G D+ + Sbjct: 260 DHAVDAFSLKLCNMGGIANTLKVAAVAEAAG----ISSYGGTMLDSTVG 304 >5FJT-A nrPDB Length = 368 Score = 45.6 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 38/84 (45%), Gaps = 1/84 (1%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLK 343 + + ++ IE P +++D ++ + I D+ ++ + + A++ A + +K Sbjct: 205 LDPFGLLLIEQPLEEEDVLGHAELARRIQTPICLDE-SIVSARAAADAIKLGAVQIVNIK 263 Query: 344 VNQIGSVTEAIQACKLAQENGWGV 367 ++G EA + + +G V Sbjct: 264 PGRVGGYLEARRVHDVCAAHGIPV 287 >3R25-A nrPDB Length = 401 Score = 44.9 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 56/302 (18%), Positives = 104/302 (34%), Gaps = 48/302 (15%) Query: 65 AVDH-INSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGA 123 AV ++ + P LI G + E L +M+ ++ NAI GV +A+ A Sbjct: 48 AVKTMVDEYLKPILI--GKNANNIEDLWQMMM-VNAYWRNGPVINNAISGVDMALWDIKA 104 Query: 124 AERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMR 183 +PL++ G S +PV +HA + + Sbjct: 105 KLAGMPLHQ---LFGGKSRDAIPV--------YTHATSDT---------------MEG-- 136 Query: 184 LGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIG 243 +Y ++G ++ Y +G GG ++ + + Y + Sbjct: 137 ----IYDLVEGFLEKGYKHIRCQLGFYGGVPTDLHTTQNP-------TEGSYYDQDQY-- 183 Query: 244 MDVAASEFYR-DGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWA 302 MD + F KY F D + +Q ++ V Y IED + Sbjct: 184 MDNTLTMFKSLREKYGNQFHILHDVHERLFPNQAIQFAKE-VEQYKPYFIEDILPPNQTE 242 Query: 303 AWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQE 362 + + + +L NP+ + + + + + V+QIG +T A++ L Q Sbjct: 243 WLDNIRSQSSVSLGLGELF-NNPEEWKSLIANRRIDFIRCHVSQIGGITPALKLGHLCQN 301 Query: 363 NG 364 G Sbjct: 302 FG 303 >2PGW-A nrPDB Length = 384 Score = 44.9 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 2/105 (1%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLK 343 + Y + IE P A + VGI IV D T + ++A + + + Sbjct: 213 LEKYDIEFIEQPTVSWSIPAMAHVREKVGIPIVADQAAFT-LYDVYEICRQRAADMICIG 271 Query: 344 VNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGL 388 +IG + ++A +A+ G + + H S T T A+ +GL Sbjct: 272 PREIGGIQPMMKAAAVAEAAGLKICI-HSSFTTGITTCAEHHIGL 315 >4GFI-A nrPDB Length = 329 Score = 43.7 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 41/97 (42%), Gaps = 7/97 (7%) Query: 274 DQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQI-VGDDLTVTNPKRIERAV 332 D Y + + IE P A A + + + D +V + + + + Sbjct: 184 DDNIEYYLKLAAELKISLIEQPLP----AGKDAMLARIEHPVLICADESVHSTEDLA-GL 238 Query: 333 EEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMV 369 ++ + + +K+++ G +TEA+ A+ G+ +MV Sbjct: 239 RDRY-DAINIKLDKTGGLTEALVMKAEAERLGFTIMV 274 >3S47-A nrPDB Length = 401 Score = 41.8 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 44/112 (39%), Gaps = 6/112 (5%) Query: 255 GKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIED--PFDQDDWAAWSKFTANVG 312 KY F D + +Q +D V Y IED P DQ++W + + Sbjct: 196 EKYGYKFHILHDVHERLFPNQAVQFAKD-VEKYKPYFIEDILPPDQNEWLG--QIRSQTS 252 Query: 313 IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENG 364 + +L NP + + + + + V+QIG +T A++ L G Sbjct: 253 TPLATGELF-NNPMEWKSLIANRQVDFIRCHVSQIGGITPALKLGSLCAAFG 303 >3RO6-B nrPDB Length = 356 Score = 41.0 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 42/113 (37%), Gaps = 9/113 (7%) Query: 266 DPSRYITGDQLGALYQDFVRDYPVVSIEDPFD--QDDWAAWSKFTANVGIQIVGDDLTVT 323 DP++ D L V++ + IE PF + DW + +I D+ + Sbjct: 190 DPNQSYDRDGLL-RLDRLVQELGIEFIEQPFPAGRTDW--LRALPKAIRRRIAADESLLG 246 Query: 324 NPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENG----WGVMVSHR 372 A AC +K+ + G + A + +A+ G WG M R Sbjct: 247 PADAFALAAPPAACGIFNIKLMKCGGLAPARRIATIAETAGIDLMWGCMDESR 299 >3MWC-A nrPDB Length = 400 Score = 40.2 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 32/75 (42%), Gaps = 1/75 (1%) Query: 293 EDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTE 352 E P + + + I D+ + + + E + N +K+ ++G + E Sbjct: 236 EQPLHYEALLDLKELGERIETPICLDESLI-SSRVAEFVAKLGISNIWNIKIQRVGGLLE 294 Query: 353 AIQACKLAQENGWGV 367 AI+ K+A +NG + Sbjct: 295 AIKIYKIATDNGIKL 309 >1JPD-X nrPDB Length = 324 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 41/104 (39%), Gaps = 6/104 (5%) Query: 266 DPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNP 325 D + + L A + D V +E P D AA F + I D+ T Sbjct: 179 DANESWRAEGLAAR-CQLLADLGVAMLEQPLPAQDDAALENFIHPL--PICADESCHT-- 233 Query: 326 KRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMV 369 R + + +K+++ G +TEA+ A+ G+ +M+ Sbjct: 234 -RSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLML 276 >3UXL-A nrPDB Length = 383 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQI-VGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSV 350 IE+P Q D+ + + + + + +G++ P+ + +A+ AC + +IG V Sbjct: 244 IEEPTLQHDYEGHQRIQSKLNVPVQMGENWL--GPEEMFKALSIGACRLAMPDAMKIGGV 301 Query: 351 TEAIQACKLAQENGWGVMVSH 371 T I+A LAQ+ G M SH Sbjct: 302 TGWIRASALAQQFGIP-MSSH 321 >4MGG-A nrPDB Length = 369 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 49/126 (38%), Gaps = 18/126 (14%) Query: 290 VSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGS 349 V IE P + V D++ + P + R + E A +C+ LK++++G Sbjct: 217 VYIEQPCLTY--EESVSIRRRTALPFVLDEV-IDGPNTLVRGIAEDAMDCINLKISKVGG 273 Query: 350 VTEAIQACKLAQENGW-------------GVMVSH--RSGETEDTFIADLVVGLCTGQIK 394 +T+A L +G ++H RS +E TF A T I Sbjct: 274 LTKAKLMRDLCIAHGIPMTIEDTWGGDIVTAAIAHLARSTPSEFTFSATDFNSYGTVDIA 333 Query: 395 TGAPCR 400 GAP R Sbjct: 334 EGAPKR 339 >4GIR-A nrPDB Length = 422 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 53/303 (17%), Positives = 97/303 (32%), Gaps = 50/303 (16%) Query: 65 AVDH-INSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGA 123 AV ++ + P LI G E L +M+ ++ NAI GV +A+ A Sbjct: 69 AVKTMVDEYLKPLLI--GKDANNIEDLWQMMM-VNAYWRNGPVINNAISGVDMALWDIKA 125 Query: 124 AERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMR 183 +PL++ G S + V +HA + + + Sbjct: 126 KIANMPLHQ---LFGGKSRDAIQV--------YTHATSDT---------------MEGL- 158 Query: 184 LGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIG 243 Y + ++ Y +G GG NI + Y + I Sbjct: 159 -----YEQVDKYLEQGYQHIRCQLGFYGGVPENIQTAQNP-------TQGSYYDQDQYIE 206 Query: 244 MDVAASEFYRD--GKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 V E +++ KY F D + +Q + + Y IED Sbjct: 207 NTV---EMFKNLREKYGKQFHILHDVHERLFPNQAIQFAKQ-IEQYNPFFIEDILPPSQT 262 Query: 302 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 361 + + +L NP+ + + + + + V+QIG +T A++ + Sbjct: 263 EWLDNIRNQSSVSLALGELF-NNPEEWKALIINRRVDFIRCHVSQIGGITPALKLGHFCE 321 Query: 362 ENG 364 G Sbjct: 322 SFG 324 >3TTE-A nrPDB Length = 383 Score = 37.9 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 35/88 (39%), Gaps = 2/88 (2%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLK 343 + DY + IE+P Q++ + + I I + P+ A+ A + ++ Sbjct: 236 LADYDLTWIEEPVPQENLSGHAAVRERSEIPIQAGENWWF-PRGFAEAIAAGASDFIMPD 294 Query: 344 VNQIGSVTEAIQACKLAQENGWGVMVSH 371 + ++G +T + A M SH Sbjct: 295 LMKVGGITGWLNVAGQADAASIP-MSSH 321 >3UGV-A nrPDB Length = 390 Score = 37.9 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 44/80 (55%), Gaps = 5/80 (6%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQI-VGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSV 350 IE+P D++ +++ ++ + +G++ P+ + +A++ AC+ ++ +IG V Sbjct: 250 IEEPVVYDNFDGYAQLRHDLKTPLMIGENFY--GPREMHQALQAGACDLVMPDFMRIGGV 307 Query: 351 TEAIQACKLAQENGWGVMVS 370 + ++A +A WG+ +S Sbjct: 308 SGWMRAAGVAGA--WGIPMS 325 >2QVH-A nrPDB Length = 327 Score = 37.9 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 283 FVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLL 342 + + + +E P D ++ V + I D+ ++ + R + +A + ++L Sbjct: 146 LLDRFELEYVEQPCATVD--ELAEVRRRVSVPIAADE-SIRRAEDPLRVRDAEAADVVVL 202 Query: 343 KVNQIGSVTEAIQACKLAQENGWGVMVS 370 KV +G V A +LA+E G V+VS Sbjct: 203 KVQPLGGV---RAALRLAEECGLPVVVS 227 >4M0X-A nrPDB Length = 371 Score = 37.5 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 39/95 (41%), Gaps = 1/95 (1%) Query: 273 GDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAV 332 + + + D V E P + + ++ + I I+ D+ +VT ++ Sbjct: 202 SELEAHRWLPILADAGVTVAEQPIARWNTDGLARLRDKLSIPIMADE-SVTTVQQAIALA 260 Query: 333 EEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGV 367 + A + +K+ + G ++ A + +A+ +G Sbjct: 261 DAGAVSAFAIKIPKSGGLSRAREIAAIAEASGLAC 295 >3I6T-A nrPDB Length = 381 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 31/76 (40%), Gaps = 3/76 (3%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE P ++ V + ++ D+ ++ P+ + E + + +K+ + G +T Sbjct: 223 IEQPVKAHLRGLMARIRDAVDVPLLADE-SIFGPEDMAEHPE--IADGVSIKIMKSGGLT 279 Query: 352 EAIQACKLAQENGWGV 367 A ++A G Sbjct: 280 RAQTVARMAAARGLSA 295 >1MUC-A nrPDB Length = 373 Score = 36.8 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 32/79 (40%), Gaps = 1/79 (1%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 + IE P + + + I+ D+ ++ + + + A + LK+ + G Sbjct: 220 IDLIEQPISRINRGGQVRLNQRTPAPIMADE-SIESVEDAFSLAADGAASIFALKIAKNG 278 Query: 349 SVTEAIQACKLAQENGWGV 367 ++ ++A+ G G+ Sbjct: 279 GPRAVLRTAQIAEAAGIGL 297 >2CHR-A nrPDB Length = 370 Score = 36.8 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 49/109 (44%), Gaps = 5/109 (4%) Query: 274 DQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVE 333 +Q+ ++Y + V IE P +++ A + + N + I+ D+ T + A Sbjct: 201 EQVASVYIPELEALGVELIEQPVGRENTQALRRLSDNNRVAIMADESLSTLASAFDLA-R 259 Query: 334 EKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIA 382 +++ + LK+ +G V+ + +A+ +G ++ G D+ I Sbjct: 260 DRSVDVFSLKLCNMGGVSATQKIAAVAEASG----IASYGGTMLDSTIG 304 >2OG9-A nrPDB Length = 393 Score = 36.4 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 32/79 (40%), Gaps = 1/79 (1%) Query: 287 YPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQ 346 + +V IE+P D D + I ++ T+ + +A + L+ + Sbjct: 233 FNLVWIEEPLDAYDHEGHAALALQFDTPIATGEML-TSAAEHGDLIRHRAADYLMPDAPR 291 Query: 347 IGSVTEAIQACKLAQENGW 365 +G +T ++ LA+ G Sbjct: 292 VGGITPFLKIASLAEHAGL 310 >3FCP-A nrPDB Length = 381 Score = 36.4 bits (83), Expect = 0.028, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 V IE P D AA + + + I+ D+ T + ++ LK+ + G Sbjct: 221 VDLIEQPVSAHDNAALVRLSQQIETAILADEAVAT-AYDGYQLAQQGFTGAYALKIAKAG 279 Query: 349 SVTEAIQACKLAQENGWGV 367 + ++AQ G G+ Sbjct: 280 GPNSVLALARVAQAAGIGL 298 >5X3E-A nrPDB Length = 449 Score = 36.0 bits (82), Expect = 0.031, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 214 APNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDL--DFKSPTDPSRYI 271 A + + E + EAI +GY + +V + V E Y + YDL D ++ R I Sbjct: 187 ADRLSTSREITDRYCEAIKLSGYNDDMVCSVFVTYVEIYNNYCYDLLEDARNGVLTKREI 246 Query: 272 TGDQLGALYQDFVRDYPVVSIEDPFD 297 D+ +Y D +D V S E+ + Sbjct: 247 RHDRQQQMYVDGAKDVEVSSSEEALE 272 >3TJI-A nrPDB Length = 422 Score = 36.0 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 54/303 (17%), Positives = 94/303 (31%), Gaps = 50/303 (16%) Query: 65 AVDH-INSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGA 123 AV ++ + P +I G E L +M ++ NAI GV +A+ Sbjct: 69 AVKTLVDEYLQPLMI--GRDANNIEDLWQMM-NVNAYWRNGPLMNNAISGVDMALWDIKG 125 Query: 124 AERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMR 183 +PLY+ G S +P SHA + +A+ Sbjct: 126 QLAGMPLYQ---LFGGKSRDAIP--------AYSHASGET---------------LEAL- 158 Query: 184 LGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIG 243 + ++ +I Y +G GG + A + ++ + Sbjct: 159 -----FASVDALIAQGYRHIRCQLGFYGGTPSALHAPDNPTP-------GAWFDQQEYMS 206 Query: 244 MDVAASEFYR--DGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDW 301 V E + KY D + Q L + P IED Sbjct: 207 NTV---EMFHALREKYGWKLHILHDVHERLFPQQAVQLAKQLEPFQPYF-IEDILPPQQS 262 Query: 302 AAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 361 A + + + +L NP + + + + V+QIG +T A++ L Q Sbjct: 263 AWLEQVRQQSCVPLALGELF-NNPAEWHDLIVNRRIDFIRCHVSQIGGITPALKLAHLCQ 321 Query: 362 ENG 364 G Sbjct: 322 AFG 324 >5HQA-A nrPDB Length = 669 Score = 35.6 bits (81), Expect = 0.044, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 35/85 (41%) Query: 253 RDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVG 312 ++ KY +DF + + D+ + V S P+D D AA +K++ G Sbjct: 291 KNTKYYMDFAAKYGFDGVLVEGWNTGWDGDWFFNGDVFSFTQPYDDFDIAALTKYSKQTG 350 Query: 313 IQIVGDDLTVTNPKRIERAVEEKAC 337 +Q++G T N + + + Sbjct: 351 VQLIGHHETSGNVSNYRKQMADAFA 375 >2PP0-A nrPDB Length = 398 Score = 35.6 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLK 343 + + ++ IE+P D D ++ A + I ++ T+ + E+ + A + + Sbjct: 243 MEQFNLIWIEEPLDAYDIEGHAQLAAALDTPIATGEML-TSFREHEQLILGNASDFVQPD 301 Query: 344 VNQIGSVTEAIQACKLAQENG 364 ++G ++ ++ LA ++G Sbjct: 302 APRVGGISPFLKIMDLAAKHG 322 >3DGB-A nrPDB Length = 382 Score = 35.2 bits (80), Expect = 0.056, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 289 VVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIG 348 + IE P +++ A + A+ I+ D+ ++ + E A + LK+ + G Sbjct: 222 IDLIEQPISRNNRAGMVRLNASSPAPIMADE-SIECVEDAFNLAREGAASVFALKIAKNG 280 Query: 349 SVTEAIQA 356 ++ Sbjct: 281 GPRATLRT 288 >3TW9-A nrPDB Length = 442 Score = 34.5 bits (78), Expect = 0.093, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 1/85 (1%) Query: 280 YQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNC 339 + Y + +EDP ++ I +L V N + ++ + + Sbjct: 261 LAKTLEQYQLFYLEDPVAPENIDWLKMLRQQSSTPISMGELFV-NVNEWKPLIDNRLIDY 319 Query: 340 LLLKVNQIGSVTEAIQACKLAQENG 364 + V+ IG +T A + ++ NG Sbjct: 320 IRCHVSTIGGITPARKLAVYSELNG 344 >3ZVH-B nrPDB Length = 438 Score = 34.5 bits (78), Expect = 0.097, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 49/146 (33%), Gaps = 12/146 (8%) Query: 257 YDLDFKSPTDPSRYITGDQLGALYQDFVRDY-PV-VSIEDPFDQDD----WAAWSKFTAN 310 + +D + + + Q P + IE P D +D A A Sbjct: 235 FHIDVYGTIGAAFDVDIKAMADYIQTLAEAAKPFHLRIEGPMDVEDRQKQMEAMRDLRAE 294 Query: 311 VG-----IQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGW 365 + ++V D+ T + ++ + KA + + +K +G V A + NG Sbjct: 295 LDGRGVDAELVADEWCNT-VEDVKFFTDNKAGHMVQIKTPDLGGVNNIADAIMYCKANGM 353 Query: 366 GVMVSHRSGETEDTFIADLVVGLCTG 391 G ET + +G+ G Sbjct: 354 GAYCGGTCNETNRSAEVTTNIGMACG 379 >3ES8-A nrPDB Length = 391 Score = 34.1 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 38/96 (39%), Gaps = 7/96 (7%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE P ++D+ + I V + K+ + +++ A + + IG +T Sbjct: 220 IESPAPRNDFDGLYQLRLKTDYPI---SEHVWSFKQQQEMIKKDAIDIFNISPVFIGGLT 276 Query: 352 EAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVG 387 A +A A+ V++ G T++ + + Sbjct: 277 SAKKAAYAAEVASKDVVL----GTTQELSVGTAAMA 308 >3T6C-A nrPDB Length = 440 Score = 34.1 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 32/81 (39%), Gaps = 1/81 (1%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLK 343 + Y + +EDP ++ I +L V N + ++ K + + Sbjct: 263 LEPYQLFFLEDPVAPENTEWLKMLRQQSSTPIAMGELFV-NVNEWKPLIDNKLIDYIRCH 321 Query: 344 VNQIGSVTEAIQACKLAQENG 364 ++ IG +T A + ++ NG Sbjct: 322 ISSIGGITPAKKIAIYSELNG 342 >3T8Q-A nrPDB Length = 370 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 15/102 (14%), Positives = 39/102 (38%), Gaps = 2/102 (1%) Query: 266 DPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNP 325 D + +Q + + + E+P ++ + T + I + G + Sbjct: 185 DANSCYGPEQAIEV-GKMLEQNGISHYEEPCPYWEYEQTQQVTNALSIDVTGGEQDC-EL 242 Query: 326 KRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGV 367 + R +E KA + + + +G +T ++ ++A + G Sbjct: 243 QNWRRMIEMKAVDIVQPDICYLGGITRTLRVAEMAHKAGLPC 284 >2PGE-A nrPDB Length = 377 Score = 32.9 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 13/90 (14%) Query: 284 VRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKAC------ 337 + + + SIE P Q W+ + AN + I D+ + I E+++ Sbjct: 231 LSQFHLHSIEQPIRQHQWSEMAALCANSPLAIALDE------ELIGLGAEQRSAMLDAIR 284 Query: 338 -NCLLLKVNQIGSVTEAIQACKLAQENGWG 366 ++LK + +G A Q +LA+E G G Sbjct: 285 PQYIILKPSLLGGFHYAGQWIELARERGIG 314 >4IHC-A nrPDB Length = 440 Score = 32.5 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 1/85 (1%) Query: 280 YQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNC 339 + Y + +EDP ++ I +L V N + ++ K + Sbjct: 259 LAKTLEPYQLFYLEDPVAPENIDWLRMLRQQSSTPISMGELFV-NINEWKPLIDNKLIDY 317 Query: 340 LLLKVNQIGSVTEAIQACKLAQENG 364 + V+ IG +T A + ++ NG Sbjct: 318 IRCHVSTIGGITPAKKLAVYSELNG 342 >4PG8-A nrPDB Length = 468 Score = 31.8 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 17/134 (12%) Query: 49 LRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVE--QEKLDNLMLELDGTENKSK- 105 +RD K+R L + +N + + + V+ + +D L L +NK Sbjct: 64 VRDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVMGGIEPTVDWLRTAL---KNKKHV 120 Query: 106 FGANA-ILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLA 164 AN +L V L + + A E + L + A +AG +P N IN G +A N Sbjct: 121 ITANKDLLAVHLKLLEDLAEENGVAL-KFEASVAGG------IPIVNAINNGLNANN--- 170 Query: 165 MQEFMILPVGAESF 178 + +FM + G +F Sbjct: 171 ISKFMGILNGTSNF 184 >3EKG-A nrPDB Length = 404 Score = 31.4 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 39/91 (42%), Gaps = 4/91 (4%) Query: 285 RDYPVVSIEDPFDQDDWAAWSKF--TANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLL 342 R+Y + IE+ DD+ +++ A G+ + + T +E C+ + Sbjct: 234 REYGLKWIEEALPPDDYWGYAELRRNAPTGMMVTTGEHEATRWG-FRMLLEMGCCDIIQP 292 Query: 343 KVNQIGSVTEAIQACKLAQENGWGVMVSHRS 373 V G VTE ++ LA + ++V H S Sbjct: 293 DVGWCGGVTELLKISALADAHN-ALVVPHGS 322 >4A35-A nrPDB Length = 441 Score = 31.4 bits (70), Expect = 0.76, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 40/100 (40%), Gaps = 5/100 (5%) Query: 266 DPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTAN---VGIQIVGDDLTV 322 D ++ + + P+ IE+P DD + + +GI I + Sbjct: 251 DANQRWDVPEAVEWMSKLAKFKPL-WIEEPTSPDDILGHATISKALVPLGIGIATGEQ-C 308 Query: 323 TNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQE 362 N ++ ++ KA L + ++GSV E + +A++ Sbjct: 309 HNRVIFKQLLQAKALQFLQIDSCRLGSVNENLSVLLMAKK 348 >3A04-A nrPDB Length = 372 Score = 31.0 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 47/128 (36%), Gaps = 11/128 (8%) Query: 171 LPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEA 230 +P G F + + +Y ++ K + D FA + EA+ + E Sbjct: 78 MPSGKFHFGHKLTVDQLIY------LQKNGFKVFVAIADAEAFAVRRIGREEAVRIAVEE 131 Query: 231 IDKAGYTEKIVIGMDVAASEFY-RDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPV 289 I +G+D +EFY + + F+ S +T ++ A+Y + + Sbjct: 132 YIA----NMIALGLDPKDTEFYFQTNRGTPYFRLIQLFSGKVTAAEMEAIYGELTPAKMM 187 Query: 290 VSIEDPFD 297 S+ D Sbjct: 188 ASLTQAAD 195 >2Z8X-A nrPDB Length = 617 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 28/110 (25%), Positives = 41/110 (37%), Gaps = 20/110 (18%) Query: 178 FRDAMRLGAEVYHTLKGVIKDKYGKDATNVG-------------DEGGFAPNILENSEAL 224 F DAM + YH L Y + +G D G P I N ++ Sbjct: 18 FSDAMAITLYSYHNLDNGFAAGYQHNGFGLGLPATLVTALLGGTDSQGVIPGIPWNPDSE 77 Query: 225 ELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGD 274 +L +A+ KAG+T + AS+ DGK D + + Y T Sbjct: 78 KLALDAVKKAGWTP-------ITASQLGYDGKTDARGTFFGEKAGYTTAQ 120 >3G68-A nrPDB Length = 352 Score = 30.6 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Query: 338 NCLLLKVNQIGSVTEAIQACKLAQENG--WGVMVSHRSGETEDTFIADLVVGLCTGQIKT 395 N L++ V+Q GS A KLA++ G M ++ ++ I+D ++ + G+ K+ Sbjct: 83 NTLVVGVSQGGSSYSTYNAMKLAEDKGCKIASMAGCKNALIDE--ISDYILTVNCGEEKS 140 Query: 396 GAPCRSERLAKYNQLM 411 GA + K N ++ Sbjct: 141 GAKTKGYYCTKLNLML 156 >1FHV-A nrPDB Length = 323 Score = 30.2 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 7/83 (8%) Query: 289 VVSIEDPFD-QDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347 + +E+P +DD A+++ T GI I D+ ++ P EE +++K Sbjct: 189 IAFLEEPCKTRDDSRAFARET---GIAIAWDE-SLREP-DFAFVAEEGV-RAVVIKPTLT 242 Query: 348 GSVTEAIQACKLAQENGWGVMVS 370 GS+ + + + A G ++S Sbjct: 243 GSLEKVREQVQAAHALGLTAVIS 265 >1KKR-A nrPDB Length = 413 Score = 30.2 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 40/108 (37%), Gaps = 10/108 (9%) Query: 292 IEDPFDQ----DDWAAWSKFTANV-----GIQIVGDDLTVTNPKRIERAVEEKACNCLLL 342 IE P D D + T + G++IV D+ T + I + +C+ + + Sbjct: 272 IEGPVDAGNKPDQIRMLTAITKELTRLGSGVKIVADEWCNT-YQDIVDFTDAGSCHMVQI 330 Query: 343 KVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCT 390 K +G + + A ++G ETE + + V L Sbjct: 331 KTPDLGGIHNIVDAVLYCNKHGMEAYQGGTCNETEISARTCVHVALAA 378 >5XD7-A nrPDB Length = 368 Score = 29.8 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 266 DPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIV 316 D + +T +Q L + V Y + E+P DD+ +++ N I + Sbjct: 198 DANYSLTVEQAIKLSKA-VEQYDITWFEEPTLPDDYKGFAEIADNTAIPLA 247 >3H7V-A nrPDB Length = 330 Score = 29.8 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Query: 277 GALYQDFVRDY---PVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVE 333 + ++ + + +E P D W A V I D+ +V + ++R V+ Sbjct: 175 ANRWFAWLDRHGNGKIEYVEQPLPPDQWQALLSLAQTVTTAIALDE-SVVSAAEVQRWVD 233 Query: 334 EKACNCLLLKVNQIG 348 ++K G Sbjct: 234 RGWPGFFVIKTALFG 248 >3ERV-A nrPDB Length = 236 Score = 29.5 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 252 YRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIED----PFDQDDWAAW 304 Y + L K + + +TG + LY+ PVV I + P D+D++ W Sbjct: 108 YHGPLFQLAKKYLPNKAVDLTGKSIEELYKSVKAGQPVVIITNATFAPLDEDEFTTW 164 >3SJN-A nrPDB Length = 374 Score = 29.5 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 37/80 (46%), Gaps = 2/80 (2%) Query: 292 IEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVT 351 IE+P D ++ K + V +I G + ++T + + + + + + + G +T Sbjct: 225 IEEPVLADSLISYEKLSRQVSQKIAGGE-SLTTRYEFQEFITKSNADIVQPDITRCGGIT 283 Query: 352 EAIQACKLAQENGWGVMVSH 371 E + +AQ NG ++ H Sbjct: 284 EMKKIYDIAQMNG-TQLIPH 302 >4WMZ-A nrPDB Length = 539 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 53/119 (44%), Gaps = 8/119 (6%) Query: 83 SVVEQEKLDNLMLEL---DGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAG 139 + +++ +D+LM DG + + AN ++GV + AA L H+A+ Sbjct: 277 DIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILL-HLAERPD 335 Query: 140 NSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKD 198 L V++GG +QE +P+ ++ ++ +R+ ++ + V+KD Sbjct: 336 VQQE-LYEEQMRVLDGGKKELTYDLLQE---MPLLNQTIKETLRMHHPLHSLFRKVMKD 390 >6ILH-A nrPDB Length = 521 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 21/52 (40%), Gaps = 19/52 (36%) Query: 147 VPAFNVINGGSHAG------NKLAMQEFMILPVGAESFRDAMRLGAEVYHTL 192 P N+I GG+ A N+L M +M R+ E+YH + Sbjct: 200 TPMMNIIPGGAVAKPFITYHNELDMNLYM-------------RIAPELYHKM 238 >4IL2-A nrPDB Length = 426 Score = 29.1 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 16/106 (15%), Positives = 39/106 (36%), Gaps = 2/106 (1%) Query: 255 GKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQ 314 K+ D D +T + A + + DY + +EDP ++ + + Sbjct: 223 NKFGFDEHLLHDMHHRLTPIE-AARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTP 281 Query: 315 IVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLA 360 I ++ + ++ +EE+ + + + G +T + A Sbjct: 282 IAVGEVF-NSIWDCKQLIEEQLIDYIRTTLTHAGGITGMRRIADFA 326 >5KR3-A nrPDB Length = 479 Score = 29.1 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 163 LAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSE 222 LA EFM F A+++G +V ++D A GD GFAP ++ Sbjct: 402 LAALEFMADKDARTPFDPALKVGPKVS---AAALEDGMIARAMPHGDILGFAPPLVTTRA 458 Query: 223 ALELVKEAIDKA 234 ++ + +A Sbjct: 459 EVDEIVGIAKQA 470 >5OLC-A nrPDB Length = 396 Score = 29.1 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 29/77 (37%), Gaps = 1/77 (1%) Query: 285 RDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKV 344 + + E+P +D+ + + N I I G + +R ++ + + Sbjct: 220 EKFDISWFEEPVSPEDYDGYKRLRQNTTIPISGGECEYLKYG-FKRLFDKDCVDIAQPDI 278 Query: 345 NQIGSVTEAIQACKLAQ 361 G +TE + LAQ Sbjct: 279 CAAGGLTEVKKIATLAQ 295 >6CHD-A nrPDB Length = 597 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 21/52 (40%), Gaps = 19/52 (36%) Query: 147 VPAFNVINGGSHAG------NKLAMQEFMILPVGAESFRDAMRLGAEVYHTL 192 P N+I GG+ A N+L M +M R+ E+YH + Sbjct: 268 TPMMNIIPGGAVAKPFITYHNELDMNLYM-------------RIAPELYHKM 306 >3K4W-A nrPDB Length = 291 Score = 28.7 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 34/143 (23%), Positives = 56/143 (39%), Gaps = 23/143 (16%) Query: 212 GFAPNILENSEALELVKEAIDKAGYTEKIVIG-----------MDVAA-SEFYRDGKYDL 259 GF P ++LEL+ E + AG + + +G DVAA ++ Y D + + Sbjct: 37 GFEPAPSAEEKSLELMFEEMAAAGIEQGVCVGRNSSVLGSVSNADVAAVAKAYPDKFHPV 96 Query: 260 DFKSPTDPSRYITG-DQLGALYQDFVRDYPVVSIEDPFDQDDWAAWS--KFTANVGIQIV 316 + ++ L V P V P DD + F + GI ++ Sbjct: 97 GSIEAATRKEAMAQMQEILDLGIRIVNLEPGV-WATPMHVDDRRLYPLYAFCEDNGIPVI 155 Query: 317 -------GDDLTVTNPKRIERAV 332 G D+T TNP+ I+R + Sbjct: 156 MMTGGNAGPDITYTNPEHIDRVL 178 >3GC2-A nrPDB Length = 323 Score = 28.3 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 37/83 (44%), Gaps = 7/83 (8%) Query: 289 VVSIEDPFD-QDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQI 347 + +E+P +DD A+++ T GI I D+ ++ A E+ +++K Sbjct: 189 IAFLEEPCKTRDDSRAFARET---GIAIAWDE-SLREADFTFEA--EEGVRAVVIKPTLT 242 Query: 348 GSVTEAIQACKLAQENGWGVMVS 370 GS+ + + A G ++S Sbjct: 243 GSLDKVREQVAAAHALGLTAVIS 265 >3U14-A nrPDB Length = 535 Score = 28.3 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 25/68 (36%), Gaps = 4/68 (5%) Query: 216 NILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQ 275 N+ +++ + + + I IG D + S FY D + P + D+ Sbjct: 403 NVSPGKTHFDILINSQELNSSVDSIKIGFDSSQSSFY----IDRHIPNVEFPRKQFFTDK 458 Query: 276 LGALYQDF 283 L A + Sbjct: 459 LAAYLEPL 466 >1X94-A nrPDB Length = 191 Score = 27.9 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 30/74 (40%) Query: 222 EALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQ 281 EA +++++ + +I + A F + GK + ++L Y+ Sbjct: 12 EAADVLQKFLSDDHNIAQIEAAAKLIADSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYR 71 Query: 282 DFVRDYPVVSIEDP 295 + YP ++I DP Sbjct: 72 ENRPGYPGIAISDP 85 >3DDM-A nrPDB Length = 392 Score = 27.9 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 14/31 (45%) Query: 108 ANAILGVSLAVCKAGAAERELPLYRHIAQLA 138 A AI G+ +A+C A PL+ + Sbjct: 114 AQAIAGLDIALCDLAARRAGQPLWAWLGGSG 144 >3AGK-A nrPDB Length = 373 Score = 27.9 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 43/122 (35%), Gaps = 4/122 (3%) Query: 221 SEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALY 280 EA L+ +K IV G +A EF D K P Q Sbjct: 204 EEASNLLVPLAEKGVLKGVIVAGPGLAKQEFVEGNYLDYRLKKILAPELVDVAYQGLQGL 263 Query: 281 QDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCL 340 ++ V V +E +D A +F ++ G + V K +E A+E A L Sbjct: 264 KEAVMKAEKV-VEAQMYRDAVNAMEEFKLHLAK---GTGMIVYGEKDVEAALEMGAVKTL 319 Query: 341 LL 342 L+ Sbjct: 320 LI 321 >6MRP-B nrPDB Length = 220 Score = 27.9 bits (61), Expect = 8.6, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 31/81 (38%), Gaps = 8/81 (9%) Query: 214 APNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITG 273 AP + + E ++L+K+ I+ + + + F++ S T + Sbjct: 111 APEVQSSEEYIQLLKKLIESPSIPHQYWLTLQYLLKHFFK--------LSQTSSKNLLNA 162 Query: 274 DQLGALYQDFVRDYPVVSIED 294 L L+ + +P S E+ Sbjct: 163 RVLSELFSPLLFRFPAASSEN 183 >5KR5-A nrPDB Length = 479 Score = 27.9 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Query: 163 LAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSE 222 LA EFM F A+++ +V ++D A GD GFAP ++ Sbjct: 402 LAALEFMADKGARTPFDPALKVSQKV---AAAALEDGLIVRALPHGDILGFAPPLVTTRA 458 Query: 223 ALELVKEAIDKAGYTE 238 ++ + AI K + E Sbjct: 459 EVDEIV-AIAKEAFDE 473 >3VCN-A nrPDB Length = 425 Score = 27.9 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 35/97 (36%), Gaps = 2/97 (2%) Query: 265 TDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTN 324 D +T + L +D Y + +ED ++ A + + + ++ + Sbjct: 232 HDVHHRLTPIEAARLGKDL-EPYRLFWLEDSVPAENQAGFRLIRQHTTTPLAVGEIFA-H 289 Query: 325 PKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQ 361 ++ +EE+ + L V G +T + A Sbjct: 290 VWDAKQLIEEQLIDYLRATVLHAGGITNLKKIAAFAD 326 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.317 0.153 0.466 Lambda K H 0.267 0.0466 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,752,740 Number of Sequences: 36641 Number of extensions: 1004089 Number of successful extensions: 3042 Number of sequences better than 10.0: 124 Number of HSP's better than 10.0 without gapping: 96 Number of HSP's successfully gapped in prelim test: 79 Number of HSP's that attempted gapping in prelim test: 2645 Number of HSP's gapped (non-prelim): 194 length of query: 434 length of database: 10,336,785 effective HSP length: 100 effective length of query: 334 effective length of database: 6,672,685 effective search space: 2228676790 effective search space used: 2228676790 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 61 (27.9 bits)