BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08590 (195 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5TBY-C nrPDB 399 e-112 6FSA-D nrPDB 316 4e-87 5H53-C nrPDB 243 6e-65 1W7I-B nrPDB 229 5e-61 3JAX-C nrPDB 220 3e-58 2W4G-C nrPDB 216 6e-57 1CLM-A nrPDB 117 5e-27 1GGZ-A nrPDB 116 7e-27 6O20-F nrPDB 115 1e-26 2F2P-A nrPDB 115 1e-26 2N6A-A nrPDB 115 1e-26 4E53-A nrPDB 115 2e-26 3WFN-B nrPDB 114 3e-26 3EK4-A nrPDB 113 5e-26 5A2H-A nrPDB 113 6e-26 4IL1-A nrPDB 112 7e-26 4OY4-A nrPDB 112 7e-26 3U0K-A nrPDB 112 1e-25 6HCS-A nrPDB 112 1e-25 4I2Y-A nrPDB 112 1e-25 5I0I-E nrPDB 111 2e-25 3JBH-C nrPDB 108 2e-24 5UKG-A nrPDB 105 1e-23 1SR6-C nrPDB 104 3e-23 2L1W-A nrPDB 101 2e-22 3I5I-C nrPDB 100 3e-22 2LC5-A nrPDB 100 5e-22 2LMV-A nrPDB 94 3e-20 1LKJ-A nrPDB 94 3e-20 2LHI-A nrPDB 94 5e-20 4DS7-A nrPDB 93 9e-20 1GGW-A nrPDB 92 1e-19 5W1A-B nrPDB 91 2e-19 2BL0-B nrPDB 87 5e-18 2LHH-A nrPDB 86 1e-17 1N2D-A nrPDB 82 2e-16 2TN4-A nrPDB 75 2e-14 1DTL-A nrPDB 75 2e-14 1TOP-A nrPDB 75 3e-14 2M5E-A nrPDB 70 4e-13 1FW4-A nrPDB 68 2e-12 2KN2-A nrPDB 67 4e-12 3QRX-A nrPDB 67 5e-12 2KZ2-A nrPDB 66 1e-11 2RO9-A nrPDB 65 1e-11 2ROB-A nrPDB 65 2e-11 2FCE-A nrPDB 64 3e-11 5D43-A nrPDB 60 5e-10 3IFK-A nrPDB 59 1e-09 2GGM-A nrPDB 59 1e-09 3KF9-A nrPDB 58 2e-09 2OBH-A nrPDB 56 8e-09 2LAP-A nrPDB 54 3e-08 2RO8-A nrPDB 54 6e-08 2HF5-A nrPDB 53 8e-08 2I08-A nrPDB 52 1e-07 3TZ1-A nrPDB 52 1e-07 5TBY-E nrPDB 52 2e-07 3J04-B nrPDB 50 6e-07 5H7D-E nrPDB 50 8e-07 5COC-A nrPDB 49 2e-06 4Q57-A nrPDB 49 2e-06 5B7X-A nrPDB 48 2e-06 2BL0-C nrPDB 47 4e-06 3DTP-E nrPDB 46 1e-05 5H53-B nrPDB 45 2e-05 2M8U-A nrPDB 45 2e-05 2M29-A nrPDB 45 2e-05 1F55-A nrPDB 45 2e-05 1TNP-A nrPDB 45 3e-05 2JNF-A nrPDB 44 3e-05 2M97-A nrPDB 44 3e-05 1OZS-A nrPDB 44 4e-05 1TRF-A nrPDB 44 4e-05 1I84-U nrPDB 44 5e-05 1O1A-B nrPDB 43 8e-05 2B1U-A nrPDB 42 1e-04 5VLN-A nrPDB 42 2e-04 2KSZ-A nrPDB 41 3e-04 2N7L-C nrPDB 41 3e-04 1OQP-A nrPDB 40 6e-04 4GJF-A nrPDB 40 7e-04 3FWC-A nrPDB 40 0.001 5MWC-D nrPDB 39 0.001 5VT9-A nrPDB 39 0.002 2K2A-A nrPDB 39 0.002 1C7W-A nrPDB 38 0.002 4OCI-A nrPDB 38 0.002 1JC2-A nrPDB 38 0.003 2AMI-A nrPDB 37 0.004 1M39-A nrPDB 37 0.005 4WPX-A nrPDB 37 0.006 2JOJ-A nrPDB 37 0.007 4AOM-A nrPDB 37 0.007 1H4B-A nrPDB 37 0.007 3I5H-B nrPDB 37 0.007 2OPO-A nrPDB 36 0.009 5Z1Q-A nrPDB 36 0.009 2LV7-A nrPDB 36 0.010 2K7B-A nrPDB 35 0.016 5E37-A nrPDB 35 0.020 5ZOR-A nrPDB 35 0.027 5OTJ-D nrPDB 35 0.029 1S6I-A nrPDB 35 0.029 2LVK-A nrPDB 35 0.030 2AUC-A nrPDB 34 0.037 1S6J-A nrPDB 33 0.056 2K2I-A nrPDB 33 0.082 1ZMZ-A nrPDB 33 0.085 4N5X-A nrPDB 32 0.12 4GFT-A nrPDB 32 0.15 4ZCV-A nrPDB 32 0.19 2OS8-B nrPDB 31 0.38 1JUO-A nrPDB 30 0.48 5MRA-A nrPDB 30 0.61 3O4Y-A nrPDB 30 0.62 1F4Q-A nrPDB 29 1.4 5HXV-A nrPDB 29 1.5 4BMK-A nrPDB 28 2.0 4REW-A nrPDB 28 2.2 4RED-A nrPDB 28 2.3 4D1E-A nrPDB 28 2.4 4CFH-A nrPDB 28 2.4 2K7C-A nrPDB 28 2.5 1SJJ-A nrPDB 28 2.8 3I82-A nrPDB 28 3.2 5KOH-B nrPDB 28 3.6 1GJY-A nrPDB 27 4.0 5GUP-v nrPDB 27 6.4 6DNC-BA nrPDB 27 6.8 4JWQ-A nrPDB 27 7.1 3K21-A nrPDB 27 7.1 2D8N-A nrPDB 26 9.1 3NCG-A nrPDB 26 9.1 >5TBY-C nrPDB Length = 195 Score = 399 bits (1026), Expect = e-112, Method: Compositional matrix adjust. Identities = 195/195 (100%), Positives = 195/195 (100%) Query: 1 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML 60 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML Sbjct: 1 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML 60 Query: 61 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH 120 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH Sbjct: 61 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH 120 Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN 180 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN Sbjct: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN 180 Query: 181 GCINYEAFVKHIMSS 195 GCINYEAFVKHIMSS Sbjct: 181 GCINYEAFVKHIMSS 195 >6FSA-D nrPDB Length = 199 Score = 316 bits (810), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 151/159 (94%), Positives = 156/159 (98%) Query: 37 FDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVL 96 FD SKIKIEFTPEQIEEFKEAF LFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVL Sbjct: 41 FDPSKIKIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVL 100 Query: 97 GKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 156 GKP+QEELN+KMMDF+TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV Sbjct: 101 GKPKQEELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 160 Query: 157 LATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS 195 LATLGE+LTEDEVEKLMAGQEDSNGCINYEAFVKHIM+ Sbjct: 161 LATLGEKLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAG 199 >5H53-C nrPDB Length = 153 Score = 243 bits (619), Expect = 6e-65, Method: Compositional matrix adjust. Identities = 118/153 (77%), Positives = 129/153 (84%), Gaps = 2/153 (1%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 IKIEF+ EQ +EFKEAF+L+DRT KIT Q GDVLRALG NPT AEV +VLG P Sbjct: 1 IKIEFSKEQQDEFKEAFLLYDRTGDS--KITLSQVGDVLRALGTNPTNAEVKKVLGNPSN 58 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 EE+N K ++FE FLPMLQ IS NKD GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG Sbjct: 59 EEMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 118 Query: 162 ERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMS 194 E++ E+EVE LMAGQEDSNGCINYEAFVKHIMS Sbjct: 119 EKMKEEEVEALMAGQEDSNGCINYEAFVKHIMS 151 >1W7I-B nrPDB Length = 151 Score = 229 bits (584), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 106/151 (70%), Positives = 128/151 (84%), Gaps = 2/151 (1%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 IEF +Q+EEFKEAF LFDR + KI Y QCGDV+RALGQNPT AEVL+VLG P+ +E Sbjct: 2 IEFNKDQLEEFKEAFELFDRVG--DGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDE 59 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 L ++ +DFETFLPMLQ ++KN+ GTYED++EG RVFDKEGNG VMGAELRHVL TLGE+ Sbjct: 60 LKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEK 119 Query: 164 LTEDEVEKLMAGQEDSNGCINYEAFVKHIMS 194 +TE+EVE ++AG EDSNGCINYEAF+KHI+S Sbjct: 120 MTEEEVETVLAGHEDSNGCINYEAFLKHILS 150 >3JAX-C nrPDB Length = 151 Score = 220 bits (561), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 102/151 (67%), Positives = 125/151 (82%), Gaps = 2/151 (1%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 +F+ EQ EFKEAF LFDRT + KI Y QCGDV+RALGQNPT AEV++VLG P+ +E+ Sbjct: 3 DFSEEQTAEFKEAFQLFDRTG--DGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEM 60 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 N K + FE FLPM+Q I+KNKD G +ED+VEGLRVFDKEGNGTVMGAE+RHVL TLGE++ Sbjct: 61 NLKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKM 120 Query: 165 TEDEVEKLMAGQEDSNGCINYEAFVKHIMSS 195 TE+EVE+L+AG EDSNGCINYE V+ ++S Sbjct: 121 TEEEVEQLVAGHEDSNGCINYEELVRMVLSG 151 >2W4G-C nrPDB Length = 145 Score = 216 bits (549), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 106/146 (72%), Positives = 125/146 (85%), Gaps = 2/146 (1%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 ++I +FKEAF+LFDRT + KIT Q GD++RALGQNPT AE+ ++LG P +EE+N K Sbjct: 1 DEINDFKEAFLLFDRTG--DAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKK 58 Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 + FE FLPMLQ + NKD GT+EDFVEGLRVFDKEGNGTVMGAELRHVLATLGE++TE+E Sbjct: 59 ITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEE 118 Query: 169 VEKLMAGQEDSNGCINYEAFVKHIMS 194 VE+LM GQEDSNGCINYEAFVKHIMS Sbjct: 119 VEELMKGQEDSNGCINYEAFVKHIMS 144 >1CLM-A nrPDB Length = 148 Score = 117 bits (292), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 65/151 (43%), Positives = 98/151 (64%), Gaps = 7/151 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E T EQI EFKEAF LFD+ IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 3 ELTEEQIAEFKEAFALFDKDGDG--TITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 60 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL ++ K +D+ E+ +E +VFD++GNG + AELRHV+ LGE+L Sbjct: 61 GT--IDFPEFLSLMARKMKEQDS--EEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKL 116 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 T+DEV++++ + D +G INYE FV+ ++S Sbjct: 117 TDDEVDEMIREADIDGDGHINYEEFVRMMVS 147 >1GGZ-A nrPDB Length = 148 Score = 116 bits (290), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 68/152 (44%), Positives = 99/152 (65%), Gaps = 9/152 (5%) Query: 45 EFTPEQIEEFKEAFMLFDRTPK-CEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 + T EQ+ EFKEAF LFD+ C IT + G V+R+LGQNPT+AE+ ++ + ++ Sbjct: 3 QLTEEQVTEFKEAFSLFDKDGDGC---ITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG 59 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 T +DF FL M+ K KDT E+ E RVFDK+GNG V AELRHV+ LGE+ Sbjct: 60 NGT--VDFPEFLGMMAR--KMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEK 115 Query: 164 LTEDEVEKLM-AGQEDSNGCINYEAFVKHIMS 194 L+++EV++++ A D +G +NYE FV+ ++S Sbjct: 116 LSDEEVDEMIRAADTDGDGQVNYEEFVRVLVS 147 >6O20-F nrPDB Length = 169 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 67/153 (43%), Positives = 97/153 (63%), Gaps = 7/153 (4%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 S + + T EQI EFKEAF LFD+ IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 18 GSHMADQLTEEQIAEFKEAFSLFDKDGDG--TITTKELGTVMRSLGQNPTEAELQDMINE 75 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 + T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ Sbjct: 76 VDADGNGT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 131 Query: 159 TLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 LGE+LT++EV++++ + D +G +NYE FV+ Sbjct: 132 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 164 Score = 40.0 bits (92), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 114 FLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM 173 +P H++ +F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ Sbjct: 14 LVPRGSHMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMI 73 Query: 174 AGQE-DSNGCINYEAFV 189 + D NG I++ F+ Sbjct: 74 NEVDADGNGTIDFPEFL 90 >2F2P-A nrPDB Length = 179 Score = 115 bits (288), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 66/149 (44%), Positives = 96/149 (64%), Gaps = 7/149 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDG--TITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 61 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 62 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 117 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 T++EV++++ + D +G +NYE FV+ + Sbjct: 118 TDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >2N6A-A nrPDB Length = 173 Score = 115 bits (287), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 66/150 (44%), Positives = 97/150 (64%), Gaps = 7/150 (4%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + T Sbjct: 7 TEEQIAEFKEAFSLFDK--DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 64 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+LT+ Sbjct: 65 --IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 120 Query: 167 DEVEKLMAGQE-DSNGCINYEAFVKHIMSS 195 +EV++++ + D +G +NYE FV+ + + Sbjct: 121 EEVDEMIREADIDGDGQVNYEEFVQMMTGA 150 >4E53-A nrPDB Length = 185 Score = 115 bits (287), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 66/147 (44%), Positives = 95/147 (64%), Gaps = 7/147 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 11 QLTEEQIAEFKEAFSLFDKDGDG--TITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 68 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 69 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 124 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVK 190 T++EV++++ + D +G +NYE FV+ Sbjct: 125 TDEEVDEMIREADIDGDGQVNYEEFVQ 151 >3WFN-B nrPDB Length = 182 Score = 114 bits (285), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 66/151 (43%), Positives = 97/151 (64%), Gaps = 7/151 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 10 QLTEEQIAEFKEAFSLFDKDGDG--TITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 67 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 68 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 123 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 T++EV++++ + D +G +NYE FV+ + + Sbjct: 124 TDEEVDEMIREADIDGDGQVNYEEFVQMMTA 154 >3EK4-A nrPDB Length = 451 Score = 113 bits (283), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 66/147 (44%), Positives = 96/147 (65%), Gaps = 7/147 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 306 QLTEEQIAEFKEAFSLFDK--DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 363 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 364 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 419 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVK 190 T++EV++++ + D +G +NYE FV+ Sbjct: 420 TDEEVDEMIREADIDGDGQVNYEEFVQ 446 >5A2H-A nrPDB Length = 149 Score = 113 bits (282), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 67/152 (44%), Positives = 98/152 (64%), Gaps = 9/152 (5%) Query: 45 EFTPEQIEEFKEAFMLFDRTPK-CEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 + T +QI EFKEAF LFD+ C IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 4 QLTDDQISEFKEAFSLFDKDGDGC---ITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 T +DF FL ++ K KDT + E+ E RVFDK+ NG + AELRHV+ LGE+ Sbjct: 61 NGT--IDFPEFLNLMAR--KMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEK 116 Query: 164 LTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 LT++EV++++ + D +G INYE FVK +M+ Sbjct: 117 LTDEEVDEMIREADVDGDGQINYEEFVKVMMA 148 >4IL1-A nrPDB Length = 823 Score = 112 bits (281), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 66/147 (44%), Positives = 96/147 (65%), Gaps = 7/147 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 4 QLTEEQIAEFKEAFSLFDKDG--DGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 61 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 62 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 117 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVK 190 T++EV++++ + D +G +NYE FV+ Sbjct: 118 TDEEVDEMIREADIDGDGQVNYEEFVQ 144 >4OY4-A nrPDB Length = 415 Score = 112 bits (281), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 66/147 (44%), Positives = 96/147 (65%), Gaps = 7/147 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 11 QLTEEQIAEFKEAFSLFDK--DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGD 68 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 69 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 124 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVK 190 T++EV++++ + D +G +NYE FV+ Sbjct: 125 TDEEVDEMIREADIDGDGQVNYEEFVQ 151 >3U0K-A nrPDB Length = 442 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 66/147 (44%), Positives = 96/147 (65%), Gaps = 7/147 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 297 QLTEEQIAEFKEAFSLFDK--DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGD 354 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 355 GT--IDFPEFLIMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 410 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVK 190 T++EV++++ + D +G +NYE FV+ Sbjct: 411 TDEEVDEMIREADIDGDGQVNYEEFVQ 437 >6HCS-A nrPDB Length = 167 Score = 112 bits (279), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 65/151 (43%), Positives = 96/151 (63%), Gaps = 7/151 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDG--TITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 61 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRH + LGE+L Sbjct: 62 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKL 117 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 T++EV++++ + D +G +NYE FV+ + + Sbjct: 118 TDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 >4I2Y-A nrPDB Length = 421 Score = 112 bits (279), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 70/168 (41%), Positives = 105/168 (62%), Gaps = 10/168 (5%) Query: 25 PPPEP-ERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRAL 83 PP P + K + ++A++ ++ T EQI EFKEAF LFD+ + IT + G V+R+L Sbjct: 257 PPDGPVMQKKTMGWEATRDQL--TEEQIAEFKEAFSLFDK--DGDGTITTKELGTVMRSL 312 Query: 84 GQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKE 143 GQNPT+AE+ ++ + + T DF FL M+ K DT + E+ E RVFDK+ Sbjct: 313 GQNPTEAELQDMINEVDADGDGT--FDFPEFLTMMAR--KMNDTDSEEEIREAFRVFDKD 368 Query: 144 GNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFVK 190 GNG + AELRHV+ LGE+LT++EV++++ D +G +NYE FV+ Sbjct: 369 GNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQ 416 >5I0I-E nrPDB Length = 145 Score = 111 bits (278), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 65/149 (43%), Positives = 95/149 (63%), Gaps = 7/149 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF L D+ IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 2 QLTEEQIAEFKEAFSLADKDGDG--TITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 59 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 60 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 115 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 T++EV++++ + D +G +NYE FV+ + Sbjct: 116 TDEEVDEMIREADIDGDGQVNYEEFVQMM 144 >3JBH-C nrPDB Length = 156 Score = 108 bits (269), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 64/147 (43%), Positives = 92/147 (62%), Gaps = 6/147 (4%) Query: 50 QIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109 ++E+ +E F ++D + E KI GD+LR+L PT A V + G ++ E K + Sbjct: 8 EVEKAREHFEIYDW--EGEGKIDARDLGDLLRSLDCKPTLAMVKKNGGSDKRGE---KKL 62 Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEV 169 E FLP+ I K K+ GT EDF+EGL+V+DK NGT++ AEL HVL +LGERLT+ E Sbjct: 63 TLEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDIEC 122 Query: 170 EKLM-AGQEDSNGCINYEAFVKHIMSS 195 E++M ED +G + YE FVK I++ Sbjct: 123 EEIMRVCDEDDDGFLKYEPFVKTIIAG 149 >5UKG-A nrPDB Length = 419 Score = 105 bits (262), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 70/173 (40%), Positives = 105/173 (60%), Gaps = 10/173 (5%) Query: 23 PAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRA 82 PA P ++ K + ++AS ++ T EQI EFKEAF LFD+ + IT + G V+R+ Sbjct: 255 PANGPVMQK-KTLGWEASNGQL--TEEQIAEFKEAFSLFDK--DGDGTITTKELGTVMRS 309 Query: 83 LGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDK 142 LGQNPT+AE+ ++ + + T DF FL M+ K T E+ E RVFDK Sbjct: 310 LGQNPTEAELQDMINEVDADGDGT--FDFPEFLTMMAR--KMSYRVTEEEIREAFRVFDK 365 Query: 143 EGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFVKHIMS 194 +GNG + AELRHV+ LGE+LT++EV++++ D +G +NYE FV+ + + Sbjct: 366 DGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 418 >1SR6-C nrPDB Length = 156 Score = 104 bits (259), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 60/153 (39%), Positives = 88/153 (57%), Gaps = 7/153 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + ++I++ K+ F LFD + + + GDV R LG NP +V V G + E Sbjct: 3 LSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFAVGGTHKMGE-- 60 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 K + FE FLP + + + + GT+ D++E + FD+EG G + GAELRHVL LGERL+ Sbjct: 61 -KSLPFEEFLPAYEGLM-DCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLS 118 Query: 166 E---DEVEKLMAGQEDSNGCINYEAFVKHIMSS 195 + DE+ KL QED G + YE FVK +M+ Sbjct: 119 DEDVDEIIKLTDLQEDLEGNVKYEDFVKKVMAG 151 >2L1W-A nrPDB Length = 149 Score = 101 bits (251), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 60/151 (39%), Positives = 94/151 (62%), Gaps = 9/151 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPK-CEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + EQI +FKEAF LFD+ C IT + V+R+L QNPT+ E+ ++ + + Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGC---ITVEELATVIRSLDQNPTEEELQDMISEVDADGN 60 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T ++F+ FL ++ K KDT E+ E +VFDK+ NG + +ELRHV+ LGE+L Sbjct: 61 GT--IEFDEFLSLMAK--KVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKL 116 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 T++EVE+++ + D +G +NYE FVK +M+ Sbjct: 117 TDEEVEQMIKEADLDGDGQVNYEEFVKMMMT 147 >3I5I-C nrPDB Length = 159 Score = 100 bits (250), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 60/155 (38%), Positives = 91/155 (58%), Gaps = 8/155 (5%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T ++IEE +E F LFD + + + GD+LR LG NPT+A+V + G + E Sbjct: 2 QLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQHGGTKKMGEK 61 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYED-FVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 K+ E LP+ + +S +KDTGT D F+E + FD+EG G + AE+R+VL LGER Sbjct: 62 AYKL---EEILPIYEEMS-SKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLGER 117 Query: 164 LTEDEVEKLMAG---QEDSNGCINYEAFVKHIMSS 195 +TED+ + +ED +G I YE +K +M+ Sbjct: 118 ITEDQCNDIFTFCDIREDIDGNIKYEDLMKKVMAG 152 >2LC5-A nrPDB Length = 151 Score = 100 bits (248), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 59/149 (39%), Positives = 88/149 (59%), Gaps = 6/149 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T E+ +E+KEAF LFD+ + K+T + G V+RALG NPT+ ++ ++ ++ N Sbjct: 8 LTAEEQQEYKEAFQLFDKDN--DNKLTAEELGTVMRALGANPTKQKISEIVKDYDKD--N 63 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 + D ETFL ++ + D+ ED + +FDKE NG + +EL+HVL TLGE+LT Sbjct: 64 SGKFDQETFLTIMLEYGQEVDST--EDIKKAFEIFDKEKNGYISASELKHVLTTLGEKLT 121 Query: 166 EDEVEKLMAGQEDSNGCINYEAFVKHIMS 194 E EV+ L+ G IN + FVK I S Sbjct: 122 EQEVDDLLKEIGVEEGLINVDDFVKLITS 150 >2LMV-A nrPDB Length = 148 Score = 94.4 bits (233), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 55/149 (36%), Positives = 92/149 (61%), Gaps = 7/149 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E T EQI EFK+AF+ FD+ KI + G ++R LGQNPT+AE+ ++ + E Sbjct: 3 ELTEEQIAEFKDAFVQFDKEGTG--KIATRELGTLMRTLGQNPTEAELQDLIAEA--ENN 58 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 N ++F F ++ + ++T T E+ E ++FD++G+G + AELR V+ LGE++ Sbjct: 59 NNGQLNFTEFCGIMAK--QMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKV 116 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 T++E+++++ + D +G INYE FV I Sbjct: 117 TDEEIDEMIREADFDGDGMINYEEFVWMI 145 >1LKJ-A nrPDB Length = 146 Score = 94.0 bits (232), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 51/143 (35%), Positives = 85/143 (59%), Gaps = 6/143 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 4 LTEEQIAEFKEAFALFDKDNNG--SISSSELATVMRSLGLSPSEAEVNDLMNEIDVD--G 59 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL ++ K+ D+ ++ +E +VFDK G+G + AEL+HVL ++GE+LT Sbjct: 60 NHQIEFSEFLALMSRQLKSNDS--EQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 117 Query: 166 EDEVEKLMAGQEDSNGCINYEAF 188 + EV+ ++ D +G IN + F Sbjct: 118 DAEVDDMLREVSDGSGEINIQQF 140 Score = 35.4 bits (80), Expect = 0.017, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +F E +FDK+ NG++ +EL V+ +LG +E EV LM + D N I + F+ Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 >2LHI-A nrPDB Length = 176 Score = 93.6 bits (231), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 51/143 (35%), Positives = 85/143 (59%), Gaps = 6/143 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 5 LTEEQIAEFKEAFALFDKDNNG--SISSSELATVMRSLGLSPSEAEVNDLMNEIDVD--G 60 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL ++ K+ D+ ++ +E +VFDK G+G + AEL+HVL ++GE+LT Sbjct: 61 NHQIEFSEFLALMSRQLKSNDS--EQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 118 Query: 166 EDEVEKLMAGQEDSNGCINYEAF 188 + EV+ ++ D +G IN + F Sbjct: 119 DAEVDDMLREVSDGSGEINIQQF 141 Score = 35.0 bits (79), Expect = 0.022, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +F E +FDK+ NG++ +EL V+ +LG +E EV LM + D N I + F+ Sbjct: 12 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 70 >4DS7-A nrPDB Length = 147 Score = 92.8 bits (229), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 51/143 (35%), Positives = 85/143 (59%), Gaps = 6/143 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 5 LTEEQIAEFKEAFALFDKDNSG--SISASELATVMRSLGLSPSEAEVADLMNEIDVD--G 60 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL ++ K D+ ++ +E +VFDK G+G + AEL+HVL ++GE+LT Sbjct: 61 NHAIEFSEFLALMSRQLKCNDS--EQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 118 Query: 166 EDEVEKLMAGQEDSNGCINYEAF 188 + EV++++ D +G IN + F Sbjct: 119 DAEVDEMLREVSDGSGEINIKQF 141 Score = 34.3 bits (77), Expect = 0.032, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DS 179 +S+N +F E +FDK+ +G++ +EL V+ +LG +E EV LM + D Sbjct: 1 MSQNLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDG 60 Query: 180 NGCINYEAFV 189 N I + F+ Sbjct: 61 NHAIEFSEFL 70 >1GGW-A nrPDB Length = 140 Score = 92.4 bits (228), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 54/142 (38%), Positives = 83/142 (58%), Gaps = 8/142 (5%) Query: 54 FKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFET 113 +K+AF LFDR + T GD+LRA GQNPT AE+ + E +D E Sbjct: 7 YKQAFSLFDRHGTGRIPKT--SIGDLLRACGQNPTLAEITEI------ESTLPAEVDMEQ 58 Query: 114 FLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM 173 FL +L + G E+FV+G +VFDK+ G + ELR+VL +LGE+L+ +E+++L+ Sbjct: 59 FLQVLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELL 118 Query: 174 AGQEDSNGCINYEAFVKHIMSS 195 G +G +NY FV+ I+++ Sbjct: 119 KGVPVKDGMVNYHDFVQMILAN 140 >5W1A-B nrPDB Length = 155 Score = 91.3 bits (225), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 50/119 (42%), Positives = 72/119 (60%), Gaps = 6/119 (5%) Query: 77 GDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEG 136 GD LRAL NPT A + ++ G ++ N K + + FLP+ + K K+ G YEDF+E Sbjct: 32 GDALRALNLNPTLALIEKLGGTKKR---NEKKIKLDEFLPIYSQVKKEKEQGCYEDFIEC 88 Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQ---EDSNGCINYEAFVKHI 192 L+++DKE NGT++ AEL+H L LGE L +++VE L A ED G I Y F+ + Sbjct: 89 LKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFADCMDPEDDEGFIPYSPFLARM 147 >2BL0-B nrPDB Length = 145 Score = 87.0 bits (214), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 54/144 (37%), Positives = 83/144 (57%), Gaps = 9/144 (6%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 ++ +E F +FD+ + K++ + G LR+LG+NPT AE+ + G +LN K D Sbjct: 5 DQIQECFQIFDKDN--DGKVSIEELGSALRSLGKNPTNAELNTIKG-----QLNAKEFDL 57 Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 TF + + K T ++ ++ R DKEGNGT+ AELR +L LG+ LT EVE+ Sbjct: 58 ATFKTVYRKPIKTP-TEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEE 116 Query: 172 LMAGQEDS-NGCINYEAFVKHIMS 194 LM S +G INYE+FV +++ Sbjct: 117 LMKEVSVSGDGAINYESFVDMLVT 140 >2LHH-A nrPDB Length = 128 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 46/125 (36%), Positives = 76/125 (60%), Gaps = 6/125 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 4 LTEEQIAEFKEAFALFDKDNNG--SISSSELATVMRSLGLSPSEAEVNDLMNEIDVD--G 59 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL ++ K+ D+ ++ +E +VFDK G+G + AEL+HVL ++GE+LT Sbjct: 60 NHQIEFSEFLALMSRQLKSNDS--EQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 117 Query: 166 EDEVE 170 + E+E Sbjct: 118 DAELE 122 Score = 35.4 bits (80), Expect = 0.015, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +F E +FDK+ NG++ +EL V+ +LG +E EV LM + D N I + F+ Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 >1N2D-A nrPDB Length = 148 Score = 81.6 bits (200), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 51/143 (35%), Positives = 79/143 (55%), Gaps = 7/143 (4%) Query: 55 KEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETF 114 K+ F LFD+ K + I GD LRA+G NPT V ++ + + + Sbjct: 7 KDIFTLFDK--KGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLR-DASSLTLDQI 63 Query: 115 LPMLQHISKNKDTGT---YEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 +++ K D T EDFV+ +VFDKE G V +LR++L LGE+LT+ EV++ Sbjct: 64 TGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDE 123 Query: 172 LMAGQE-DSNGCINYEAFVKHIM 193 L+ G E DSNG I+Y+ F++ ++ Sbjct: 124 LLKGVEVDSNGEIDYKKFIEDVL 146 >2TN4-A nrPDB Length = 159 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 48/149 (32%), Positives = 82/149 (55%), Gaps = 6/149 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + E I EFK AF +FD + I+ + G V+R LGQ PT+ E+ ++ +E Sbjct: 11 LSEEMIAEFKAAFDMFDADGGGD--ISVKELGTVMRMLGQTPTKEELDAII--EEVDEDG 66 Query: 106 TKMMDFETFLPMLQHISKNKDTG-TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 + +DFE FL M+ K G + E+ E R+FD+ +G + EL + GE + Sbjct: 67 SGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRASGEHV 126 Query: 165 TEDEVEKLMA-GQEDSNGCINYEAFVKHI 192 T++E+E LM G ++++G I+++ F+K + Sbjct: 127 TDEEIESLMKDGDKNNDGRIDFDEFLKMM 155 >1DTL-A nrPDB Length = 161 Score = 75.1 bits (183), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 51/150 (34%), Positives = 88/150 (58%), Gaps = 5/150 (3%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 11 QLTEEQKNEFKAAFDIFVLGAE-DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGS 69 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGL-RVFDKEGNGTVMGAELRHVLATLGER 163 T +DF+ FL M+ K+ G E+ + L R+FDK +G + EL+ +L GE Sbjct: 70 GT--VDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGET 127 Query: 164 LTEDEVEKLMA-GQEDSNGCINYEAFVKHI 192 +TED++E+LM G ++++G I+Y+ F++ + Sbjct: 128 ITEDDIEELMKDGDKNNDGRIDYDEFLEFM 157 >1TOP-A nrPDB Length = 162 Score = 74.7 bits (182), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 50/149 (33%), Positives = 81/149 (54%), Gaps = 6/149 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + E I EFK AF +FD + I+ + G V+R LGQNPT+ E+ ++ +E Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGD--ISTKELGTVMRMLGQNPTKEELDAII--EEVDEDG 69 Query: 106 TKMMDFETFLPMLQHISKNKDTG-TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 + +DFE FL M+ K G + E+ R+FDK +G + EL +L GE + Sbjct: 70 SGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHV 129 Query: 165 TEDEVEKLMAGQEDSN-GCINYEAFVKHI 192 TE+++E LM + +N G I+++ F+K + Sbjct: 130 TEEDIEDLMKDSDKNNDGRIDFDEFLKMM 158 >2M5E-A nrPDB Length = 73 Score = 70.5 bits (171), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 32/71 (45%), Positives = 52/71 (73%), Gaps = 1/71 (1%) Query: 125 KDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCI 183 K+ + E+ +E +VFD++GNG + AELRHV+ LGE+LT+DEV++++ + D +G I Sbjct: 2 KEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHI 61 Query: 184 NYEAFVKHIMS 194 NYE FV+ ++S Sbjct: 62 NYEEFVRMMVS 72 >1FW4-A nrPDB Length = 71 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 32/66 (48%), Positives = 48/66 (72%), Gaps = 1/66 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCIN 184 DT + E+ E RVFDK+GNG + AELRHV+ LGE+LT++EV++++ + D +G +N Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 60 Query: 185 YEAFVK 190 YE FV+ Sbjct: 61 YEEFVQ 66 >2KN2-A nrPDB Length = 92 Score = 67.4 bits (163), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 32/70 (45%), Positives = 49/70 (70%), Gaps = 1/70 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCIN 184 DT E+ E +VFDK+ NG + +ELRHV+ LGE+LT++EVE+++ + D +G +N Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 63 Query: 185 YEAFVKHIMS 194 YE FVK +M+ Sbjct: 64 YEEFVKMMMT 73 >3QRX-A nrPDB Length = 169 Score = 67.0 bits (162), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 46/154 (29%), Positives = 84/154 (54%), Gaps = 7/154 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D K ++ T EQ +E +EAF LFD I + +RALG P + E+ +++ Sbjct: 14 DQKKGRVGLTEEQKQEIREAFDLFDTDGSG--TIDAKELKVAMRALGFEPKKEEIKKMIS 71 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 + ++ T +DFE FL M+ +D+ E+ ++ R+FD + +GT+ +LR V Sbjct: 72 EIDKDGSGT--IDFEEFLTMMTAKMGERDS--REEILKAFRLFDDDNSGTITIKDLRRVA 127 Query: 158 ATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVK 190 LGE LTE+E+++++A + + I+ + F++ Sbjct: 128 KELGENLTEEELQEMIAEADRNDDNEIDEDEFIR 161 >2KZ2-A nrPDB Length = 94 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 32/67 (47%), Positives = 48/67 (71%), Gaps = 1/67 (1%) Query: 125 KDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCI 183 KDT + E+ E RV DK+GNG + AELRHV+ LGE+LT++EV++++ + D +G + Sbjct: 23 KDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQV 82 Query: 184 NYEAFVK 190 NYE FV+ Sbjct: 83 NYEEFVQ 89 >2RO9-A nrPDB Length = 69 Score = 65.5 bits (158), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 32/65 (49%), Positives = 47/65 (72%), Gaps = 1/65 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E+ E RVFDK+ NG + AELRHV+ LGE+LT++EV++++ + D +G INYE FV Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFV 63 Query: 190 KHIMS 194 K +M+ Sbjct: 64 KVMMA 68 >2ROB-A nrPDB Length = 70 Score = 64.7 bits (156), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 30/65 (46%), Positives = 47/65 (72%), Gaps = 1/65 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E+ E +VFDK+ NG + +ELRHV+ LGE+LT++EVE+++ + D +G +NYE FV Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 63 Query: 190 KHIMS 194 K +M+ Sbjct: 64 KMMMT 68 >2FCE-A nrPDB Length = 70 Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 31/64 (48%), Positives = 47/64 (73%), Gaps = 1/64 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 EDFV+ +VFDKE G V +LR++L LGE+LT+ EV++L+ G E DSNG I+Y+ F+ Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFI 64 Query: 190 KHIM 193 + ++ Sbjct: 65 EDVL 68 >5D43-A nrPDB Length = 178 Score = 60.5 bits (145), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 43/147 (29%), Positives = 77/147 (52%), Gaps = 7/147 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E T +Q +E +EAF LFD + + + +RALG P + E+ +++ + +E Sbjct: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVA--MRALGFEPRKEEMKKMISEVDKE-- 79 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T + F FL ++ KDT E+ ++ R+FD + G + L+ V LGE L Sbjct: 80 ATGKISFNDFLAVMTQKMAEKDTK--EEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 Query: 165 TEDEVEKLM-AGQEDSNGCINYEAFVK 190 T++E+++++ D +G +N E F+K Sbjct: 138 TDEELQEMIDEADRDGDGEVNEEEFLK 164 >3IFK-A nrPDB Length = 90 Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 6/94 (6%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 3 QLTEEQIAEFKEAFSLFDK--DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 60 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLR 138 T +DF FL M+ K KDT + E+ E R Sbjct: 61 GT--IDFPEFLTMMAR--KMKDTDSEEEIREAFR 90 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 21/58 (36%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D NG I++ F+ Sbjct: 12 FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 >2GGM-A nrPDB Length = 172 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 41/147 (27%), Positives = 78/147 (53%), Gaps = 7/147 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E T EQ +E +EAF LFD + + + +RALG P + E+ +++ + +E Sbjct: 24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVA--MRALGFEPKKEEIKKMISEIDKE-- 79 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 T M+F FL ++ KDT E+ ++ ++FD + G + L+ V LGE L Sbjct: 80 GTGKMNFGDFLTVMTQKMSEKDT--KEEILKAFKLFDDDETGKISFKNLKRVAKELGENL 137 Query: 165 TEDEVEKLM-AGQEDSNGCINYEAFVK 190 T++E+++++ D +G ++ + F++ Sbjct: 138 TDEELQEMIDEADRDGDGEVSEQEFLR 164 >3KF9-A nrPDB Length = 149 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 7/146 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQ +E +EAF LFD I + +RALG P + E+ +++ ++ Sbjct: 2 LTEEQKQEIREAFDLFDTDGSG--TIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSG 59 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 T +DFE FL M+ +D+ E+ ++ R+FD + G + L+ V LGE +T Sbjct: 60 T--IDFEEFLQMMTAKMGERDS--REEIMKAFRLFDDDETGKISFKNLKRVAKELGENMT 115 Query: 166 EDEVEKLM-AGQEDSNGCINYEAFVK 190 ++E+++++ D +G +N E F + Sbjct: 116 DEELQEMIDEADRDGDGEVNEEEFFR 141 >2OBH-A nrPDB Length = 143 Score = 56.2 bits (134), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 40/145 (27%), Positives = 77/145 (53%), Gaps = 7/145 (4%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 T EQ +E +EAF LFD + + + +RALG P + E+ +++ + +E T Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVA--MRALGFEPKKEEIKKMISEIDKE--GT 56 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 M+F FL ++ KDT E+ ++ ++FD + G + L+ V LGE LT+ Sbjct: 57 GKMNFGDFLTVMTQKMSEKDT--KEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD 114 Query: 167 DEVEKLM-AGQEDSNGCINYEAFVK 190 +E+++++ D +G ++ + F++ Sbjct: 115 EELQEMIDEADRDGDGEVSEQEFLR 139 >2LAP-A nrPDB Length = 167 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 39/155 (25%), Positives = 83/155 (53%), Gaps = 20/155 (12%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQC---GDVLRALGQNPTQAEVLRVLGKPRQE 102 PE+IEE +EAF FD+ K Y C G+ +R +G PT+ E++ + + Sbjct: 19 LRPEEIEELREAFREFDKD-----KDGYINCRDLGNCMRTMGYMPTEMELIEL-----SQ 68 Query: 103 ELNTKM---MDFETFLPML--QHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 ++N + +DF+ F+ ++ + +++ D ++ + R FD G+G + +ELR + Sbjct: 69 QINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAM 128 Query: 158 -ATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 LG ++ ++E+++ + + +G +++E FV+ Sbjct: 129 RKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVR 163 >2RO8-A nrPDB Length = 79 Score = 53.5 bits (127), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 36/84 (42%), Positives = 50/84 (59%), Gaps = 8/84 (9%) Query: 45 EFTPEQIEEFKEAFMLFDRTPK-CEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 + T EQI EFKEAF LFD+ C IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 3 QLTDEQISEFKEAFSLFDKDGDGC---ITTKELGTVMRSLGQNPTEAELQDMINEVDADG 59 Query: 104 LNTKMMDFETFLPMLQHISKNKDT 127 T +DF FL ++ K KDT Sbjct: 60 NGT--IDFPEFLNLMAR--KMKDT 79 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 F E +FDK+G+G + EL V+ +LG+ TE E++ ++ + D NG I++ F+ Sbjct: 12 FKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLN 70 >2HF5-A nrPDB Length = 68 Score = 53.1 bits (126), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 27/53 (50%), Positives = 34/53 (64%), Gaps = 2/53 (3%) Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 +DF FL M+ K KDT + E+ E RVFDK+GNG + AELRHV+ LG Sbjct: 18 IDFPEFLTMMAR--KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 68 >2I08-A nrPDB Length = 78 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 32/79 (40%), Positives = 47/79 (59%), Gaps = 4/79 (5%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF L+D+ + IT + G V+R+LG NPT+AE+ ++ + + Sbjct: 3 QLTEEQIAEFKEAFSLYDK--DGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGN 60 Query: 105 NTKMMDFETFLPMLQHISK 123 T +DF FL M+ I K Sbjct: 61 GT--IDFPEFLTMMARIMK 77 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKH 191 F E ++DK+G+GT+ EL V+ +LG TE E++ ++ + D NG I++ F+ Sbjct: 12 FKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFLTM 71 Query: 192 I 192 + Sbjct: 72 M 72 >3TZ1-A nrPDB Length = 74 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Query: 135 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIM 193 E RV DKE G + LR +L +LG+ LTEDE+E ++A + D +G ++YE F +M Sbjct: 11 EAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFKCLMM 70 Query: 194 SS 195 SS Sbjct: 71 SS 72 >5TBY-E nrPDB Length = 166 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 45/150 (30%), Positives = 70/150 (46%), Gaps = 11/150 (7%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F QI+EFKEAF + D+ + I D ALG+ + E + + K +N Sbjct: 21 FEQTQIQEFKEAFTIMDQNR--DGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPIN 78 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 F FL M K D E + +VFD EG G + +R +L T ER + Sbjct: 79 -----FTVFLTMFGEKLKGADP--EETILNAFKVFDPEGKGVLKADYVREMLTTQAERFS 131 Query: 166 EDEVEKLMAGQ-EDSNGCINYEAFVKHIMS 194 ++EV+++ A D G ++Y+ V HI++ Sbjct: 132 KEEVDQMFAAFPPDVTGNLDYKNLV-HIIT 160 >3J04-B nrPDB Length = 143 Score = 50.1 bits (118), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 13/147 (8%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F QI+EFKEAF + D+ I D+L ++G+NPT E L + +N Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDG--FIDKEDLHDMLASMGKNPTD-EYLEGMMSEAPGPIN 57 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFV-EGLRVFDKEGNGTVMGAELRHVLATLGERL 164 F FL M D ED + FD+E +G + LR +L T+G+R Sbjct: 58 -----FTMFLTMFGEKLNGTDP---EDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRF 109 Query: 165 TEDEVEKLM-AGQEDSNGCINYEAFVK 190 T++EV+++ D G NY F + Sbjct: 110 TDEEVDEMYREAPIDKKGNFNYVEFTR 136 >5H7D-E nrPDB Length = 120 Score = 49.7 bits (117), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 29/69 (42%), Positives = 43/69 (62%), Gaps = 4/69 (5%) Query: 50 QIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109 QI+ FKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + T + Sbjct: 54 QIQAFKEAFSLFDK--DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT--I 109 Query: 110 DFETFLPML 118 DF FL M+ Sbjct: 110 DFPEFLTMM 118 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 21/58 (36%), Positives = 36/58 (62%), Gaps = 1/58 (1%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D NG I++ F+ Sbjct: 58 FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 115 >5COC-A nrPDB Length = 130 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/70 (42%), Positives = 43/70 (61%), Gaps = 4/70 (5%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 E I EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + T Sbjct: 60 ECIAEFKEAFSLFDKDG--DGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT-- 115 Query: 109 MDFETFLPML 118 +DF FL M+ Sbjct: 116 IDFPEFLTMM 125 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 37/59 (62%), Gaps = 1/59 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D NG I++ F+ Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 122 >4Q57-A nrPDB Length = 65 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 29/68 (42%), Positives = 42/68 (61%), Gaps = 4/68 (5%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 I EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + T +D Sbjct: 1 IAEFKEAFSLFDK--DGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT--ID 56 Query: 111 FETFLPML 118 F FL M+ Sbjct: 57 FPEFLTMM 64 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 1/61 (1%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKH 191 F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D NG I++ F+ Sbjct: 4 FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTM 63 Query: 192 I 192 + Sbjct: 64 M 64 >5B7X-A nrPDB Length = 156 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 36/129 (27%), Positives = 65/129 (50%), Gaps = 18/129 (13%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEV------LRVLGKPRQEELN 105 ++ ++ F +DR + KI Q G ++R+LG PT+ EV + G+ Q E Sbjct: 13 QKIRDCFNFYDR--DYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEGETFQIEQF 70 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 +M+ E P + I K VFD++ +G + ++L H L T+G+++T Sbjct: 71 ELIMEREQSKPDTREIKLRK----------AFEVFDQDKDGKIKASDLAHNLTTVGDKMT 120 Query: 166 EDEVEKLMA 174 ++EVEK+ + Sbjct: 121 KEEVEKVFS 129 >2BL0-C nrPDB Length = 142 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 43/148 (29%), Positives = 64/148 (43%), Gaps = 10/148 (6%) Query: 49 EQIEEFKEAFMLFD--RTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 +Q+ EFKEAF LFD RT IT VL+ G A + + + Sbjct: 3 DQVSEFKEAFELFDSERTGF----ITKEGLQTVLKQFGVRVEPAAFNEMFNEA--DATGN 56 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 + F FL M+ + K T + + + R FD EG G + A L+ L LG+RL Sbjct: 57 GKIQFPEFLSMMGR--RMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKP 114 Query: 167 DEVEKLMAGQEDSNGCINYEAFVKHIMS 194 E + + E G I Y+ F+ + + Sbjct: 115 HEFAEFLGITETEKGQIRYDNFINTMFT 142 >3DTP-E nrPDB Length = 196 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/160 (26%), Positives = 77/160 (48%), Gaps = 26/160 (16%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDR-----TPKCEMKITYGQCGDVLRALGQNPTQAEVL 93 S + FT Q++EFKEAF L D+ K +++ T+ +LG+ T+ E+ Sbjct: 44 GSNVFAMFTQHQVQEFKEAFQLIDQDKDGFISKNDIRATF-------DSLGRLCTEQELD 96 Query: 94 RVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYED--FVEGLRVFDKEGNGTVMGA 151 ++ + ++F FL + ++ GT E+ V +FD EG+G Sbjct: 97 SMVAEA------PGPINFTMFLTIF----GDRIAGTDEEDVIVNAFNLFD-EGDGKCKEE 145 Query: 152 ELRHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVK 190 L+ L T GE+ ++DEV++ ++ D NG I+ + F + Sbjct: 146 TLKRSLTTWGEKFSQDEVDQALSEAPIDGNGLIDIKKFAQ 185 >5H53-B nrPDB Length = 146 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 41/138 (29%), Positives = 63/138 (45%), Gaps = 12/138 (8%) Query: 50 QIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109 QI+EFKEAF + D+ + I D A+G+ + E L + K +N Sbjct: 3 QIQEFKEAFTVIDQNR--DGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEASGPIN---- 56 Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEG-LRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 F FL M K D ED + G +V D EG GT+ L +L T +R +++E Sbjct: 57 -FTVFLTMFGEKLKGADP---EDVITGAFKVLDPEGKGTIKKQFLEELLITQCDRFSQEE 112 Query: 169 VEKLMAGQE-DSNGCINY 185 ++ + A D G ++Y Sbjct: 113 IKNMWAAFSPDVGGNVDY 130 >2M8U-A nrPDB Length = 77 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 23/57 (40%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Query: 134 VEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN-GCINYEAFV 189 +E +VFD++GNG V LR VL LG+ + DE+E+++ + N G + YE FV Sbjct: 14 IEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYETFV 70 >2M29-A nrPDB Length = 171 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 39/126 (30%), Positives = 66/126 (52%), Gaps = 12/126 (9%) Query: 71 ITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHIS-KNKDTGT 129 I Y + GD +R LG PT+ E+L V + + +M F F ++ IS K ++ Sbjct: 45 IGYRELGDCMRTLGYMPTEMELLEV-----SQHVKMRMGGFVDFEEFVELISPKLREETA 99 Query: 130 YEDFVEGLRV----FDKEGNGTVMGAELRHVL-ATLGERLTEDEVEKLMAGQE-DSNGCI 183 + V LR+ FDK+ +G + AELR A LGE L E+++++ + + +G I Sbjct: 100 HMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTI 159 Query: 184 NYEAFV 189 +++ FV Sbjct: 160 DFDEFV 165 >1F55-A nrPDB Length = 77 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 4 LTEEQIAEFKEAFALFDKDNNG--SISSSELATVMRSLGLSPSEAEVNDLMNEIDVD--G 59 Query: 106 TKMMDFETFLPML 118 ++F FL ++ Sbjct: 60 NHQIEFSEFLALM 72 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +F E +FDK+ NG++ +EL V+ +LG +E EV LM + D N I + F+ Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFL 69 >1TNP-A nrPDB Length = 90 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + E I EFK AF +FD + I+ + G V+R LGQNPT+ E+ ++ +E Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGD--ISTKELGTVMRMLGQNPTKEELDAII--EEVDEDG 69 Query: 106 TKMMDFETFLPML 118 + +DFE FL M+ Sbjct: 70 SGTIDFEEFLVMM 82 Score = 32.7 bits (73), Expect = 0.089, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNGCINYEAFV 189 F +FD +G G + EL V+ LG+ T++E++ ++ ED +G I++E F+ Sbjct: 22 FKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFL 79 >2JNF-A nrPDB Length = 158 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 81/160 (50%), Gaps = 20/160 (12%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D SK+ + Q++ + AF F+ TP+ +++ Q G +L LG T++ + +++ Sbjct: 3 DVSKL----SSNQVKLLETAFRDFE-TPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLID 57 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTG-------TYEDFVEGLRVFDKEGNGTVMG 150 + + +DF++F I + G ++ E R++DKEGNG + Sbjct: 58 EF--DPFGNGDIDFDSF-----KIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYIST 110 Query: 151 AELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +R +LA L E L+ ++++ ++ + D +G +++E F+ Sbjct: 111 DVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 150 >2M97-A nrPDB Length = 69 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 39/61 (63%), Gaps = 1/61 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E+ E R+FDK+GNG + E ++ GE+LT+++V+++ + D NG I+++ F+ Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFL 62 Query: 190 K 190 K Sbjct: 63 K 63 >1OZS-A nrPDB Length = 73 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 39/57 (68%), Gaps = 1/57 (1%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVKHI 192 R+FDK +G + EL+ +L GE +TED++E+LM G ++++G I+Y+ F++ + Sbjct: 13 FRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFM 69 >1TRF-A nrPDB Length = 76 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + E I EFK AF +FD + I+ + G V+R LGQNPT+ E+ ++ +E Sbjct: 3 LSEEMIAEFKAAFDMFDADGGGD--ISTKELGTVMRMLGQNPTKEELDAII--EEVDEDG 58 Query: 106 TKMMDFETFLPML 118 + +DFE FL M+ Sbjct: 59 SGTIDFEEFLVMM 71 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 1/59 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFV 189 +F +FD +G G + EL V+ LG+ T++E++ ++ ED +G I++E F+ Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFL 68 >1I84-U nrPDB Length = 166 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 41/149 (27%), Positives = 67/149 (44%), Gaps = 12/149 (8%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 +S + F +IE+FKEAF + D+ + I + A+G+ + E L + K Sbjct: 12 SSNVFSMFDETEIEDFKEAFTVIDQN--ADGIIDKDDLRETFAAMGRLNVKNEELDAMIK 69 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEG-LRVFDKEGNGTVMGAELRHVL 157 +N F FL M K D ED + G +V D +G G++ + L +L Sbjct: 70 EASGPIN-----FTVFLTMFGEKLKGADP---EDVIMGAFKVLDPDGKGSIKKSFLEELL 121 Query: 158 ATLGERLTEDEVEKLMAG-QEDSNGCINY 185 T G R T +E++ + A D G ++Y Sbjct: 122 TTGGGRFTPEEIKNMWAAFPPDVAGNVDY 150 Score = 30.8 bits (68), Expect = 0.40, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFV 189 EDF E V D+ +G + +LR A +G ++ E+L A ++++G IN+ F+ Sbjct: 25 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN--EELDAMIKEASGPINFTVFL 81 >1O1A-B nrPDB Length = 145 Score = 43.1 bits (100), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 40/142 (28%), Positives = 64/142 (45%), Gaps = 12/142 (8%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F +IE+FKEAF + D+ + I + A+G+ + E L + K +N Sbjct: 1 FDETEIEDFKEAFTVIDQN--ADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPIN 58 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEG-LRVFDKEGNGTVMGAELRHVLATLGERL 164 F FL M K D ED + G +V D +G G++ + L +L T G R Sbjct: 59 -----FTVFLTMFGEKLKGADP---EDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRF 110 Query: 165 TEDEVEKLMAGQ-EDSNGCINY 185 T +E++ + A D G ++Y Sbjct: 111 TPEEIKNMWAAFPPDVAGNVDY 132 Score = 30.4 bits (67), Expect = 0.46, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFV 189 EDF E V D+ +G + +LR A +G ++ E+L A ++++G IN+ F+ Sbjct: 7 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN--EELDAMIKEASGPINFTVFL 63 >2B1U-A nrPDB Length = 71 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 ED R FD++G+G + ELR +A LG+ L ++E++ ++ + D +G +NYE F Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFA 65 Query: 190 KHI 192 + + Sbjct: 66 RML 68 >5VLN-A nrPDB Length = 120 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 11 QLTEEQKNEFKAAFDIFVLGAE-DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGS 69 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTY 130 T +DF+ FL M+ K+ G + Sbjct: 70 GT--VDFDEFLVMMVRSMKDDSKGKF 93 >2KSZ-A nrPDB Length = 76 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 6/74 (8%) Query: 46 FTPEQIEEFKEAFMLFDRTPK-CEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + EQI +FKEAF LFD+ C IT + V+R+L QNPT+ E+ ++ + + Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGC---ITVEELATVIRSLDQNPTEEELQDMISEVDADGN 60 Query: 105 NTKMMDFETFLPML 118 T ++F+ FL ++ Sbjct: 61 GT--IEFDEFLSLM 72 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 1/60 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 DF E +FDK+G+G + EL V+ +L + TE+E++ +++ + D NG I ++ F+ Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLS 70 >2N7L-C nrPDB Length = 141 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 6/95 (6%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 26 QLTEEQKNEFKAAFDIFVLGAE-DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGS 84 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRV 139 T +DF+ FL M+ K+ Y +G RV Sbjct: 85 GT--VDFDEFLVMMVRXMKDDSENLY---FQGRRV 114 >1OQP-A nrPDB Length = 77 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 40/63 (63%), Gaps = 1/63 (1%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEA 187 + E+ ++ R+FD + +GT+ +LR V LGE LTE+E+++++A + + I+ + Sbjct: 7 SREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDE 66 Query: 188 FVK 190 F++ Sbjct: 67 FIR 69 >4GJF-A nrPDB Length = 89 Score = 39.7 bits (91), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 3/80 (3%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + + + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 11 QLTEEQKNEFKAAFDIFVQGAE-DGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGS 69 Query: 105 NTKMMDFETFLPMLQHISKN 124 T +DF+ FL M+ K+ Sbjct: 70 GT--VDFDEFLVMMVRCMKD 87 >3FWC-A nrPDB Length = 161 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 37/146 (25%), Positives = 67/146 (45%), Gaps = 7/146 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E EQ +E EAF LFD + Y + ++ALG + E+L ++ + E Sbjct: 16 ELLEEQKQEIYEAFSLFDMNNDG--FLDYHELKVAMKALGFELPKREILDLIDEYDSE-- 71 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 +M ++ F ++ +D ++ ++FD + G + LR V LGE L Sbjct: 72 GRHLMKYDDFYIVMGEKILKRDP--LDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETL 129 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFV 189 T++E+ ++ + D +G IN F+ Sbjct: 130 TDEELRAMIEEFDLDGDGEINENEFI 155 >5MWC-D nrPDB Length = 311 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E+ E R FDK+G+G + E ++ GE+LT+++ +++ + D NG I+++ F+ Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFL 210 Query: 190 KHI 192 K + Sbjct: 211 KMV 213 >5VT9-A nrPDB Length = 152 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 67/147 (45%), Gaps = 11/147 (7%) Query: 49 EQIEEFKEAFMLFDR--TPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 E +EE EA ++ R K++ G + R LG P+ A+ K EE + Sbjct: 11 EALEEMVEADEMYARFNARASGGKVSTGDAMILARQLGLAPSYAD------KQAFEEKSG 64 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 +D+ +F + + +D ED VE FD +G + ++ ++L T GE LT Sbjct: 65 DNLDYASFQKFVGTSTHPEDN--IEDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTT 122 Query: 167 DEVEKLMAGQEDSNGCINYEAFVKHIM 193 +E L A + ++ I+Y F K ++ Sbjct: 123 EEFNAL-AAEYFTSDQIDYRQFCKAML 148 >2K2A-A nrPDB Length = 70 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 36/56 (64%), Gaps = 1/56 (1%) Query: 135 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E R++DKEGNG + +R +LA L E L+ ++++ ++ + D +G +++E F+ Sbjct: 7 EAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFM 62 >1C7W-A nrPDB Length = 81 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGER-LTEDEVEKLMA-GQEDSNGCINYEAF 188 E+ + +VFD G+G + E + ++ +GE LT+ EVE+ M ED NG I+ F Sbjct: 8 EEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEF 67 Query: 189 VKHIMSS 195 + I S Sbjct: 68 MDLIKKS 74 >4OCI-A nrPDB Length = 146 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 19/146 (13%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM--M 109 E+ KE+F+LFD + +T + ++R LG V+ N+K+ M Sbjct: 6 EDLKESFLLFD--GDGDGYLTLNEFESLVRVLGV------VMETSAIASTYNSNSKVRGM 57 Query: 110 DFETFLPMLQHI---SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 +E F + S NKD + + V DK+ G + ELR +L+T+G+ + + Sbjct: 58 SYELFTSCFSQLKTKSFNKD-----EIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQ 112 Query: 167 DEVEKLMAGQE-DSNGCINYEAFVKH 191 E+ L D G + + F+ Sbjct: 113 KEITDLFTFMGIDEQGVVKVDDFINQ 138 >1JC2-A nrPDB Length = 76 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 33/55 (60%), Gaps = 1/55 (1%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN-GCINYEAFVK 190 R+FDK +G + EL +L GE + E+++E LM + +N G I+++ F+K Sbjct: 16 FRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEFLK 70 >2AMI-A nrPDB Length = 96 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 4/81 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D K ++ T EQ +E +EAF LFD I + +RALG P + E+ +++ Sbjct: 16 DQKKGRVGLTEEQKQEIREAFDLFDTDGSG--TIDAKELKVAMRALGFEPKKEEIKKMIS 73 Query: 98 KPRQEELNTKMMDFETFLPML 118 + ++ T +DFE FL M+ Sbjct: 74 EIDKDGSGT--IDFEEFLTMM 92 Score = 34.3 bits (77), Expect = 0.032, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 35/56 (62%), Gaps = 1/56 (1%) Query: 135 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNGCINYEAFV 189 E +FD +G+GT+ EL+ + LG ++E++K+++ +D +G I++E F+ Sbjct: 34 EAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFL 89 >1M39-A nrPDB Length = 89 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 46/83 (55%), Gaps = 3/83 (3%) Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 M+F FL ++ KDT E+ ++ ++FD + G + L+ V LGE LT++E Sbjct: 1 MNFGDFLTVMTQKMSEKDTK--EEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEE 58 Query: 169 VEKLM-AGQEDSNGCINYEAFVK 190 +++++ D +G ++ + F++ Sbjct: 59 LQEMIDEADRDGDGEVSEQEFLR 81 >4WPX-A nrPDB Length = 177 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 36/162 (22%), Positives = 74/162 (45%), Gaps = 17/162 (10%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + + EQ EAF LFD + ++Y + VLRALG + + + +L + Q Sbjct: 19 KLSDEQKTRISEAFELFDSNK--DGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPA 76 Query: 105 NT----------KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELR 154 N + + T + + + +D ++ R+FD +G G + +LR Sbjct: 77 NWPHDQECPPVYRQFNLATAQALAGTLIRQRDP--RDELRRAFRLFDVDGKGMITEDDLR 134 Query: 155 HVLATLGERLTEDEVEKLMAGQEDSN--GCINYEAFVKHIMS 194 V +G + + +++ ++ + DSN G ++ + F++ +MS Sbjct: 135 KVCQQVGNNIPDADIQAMIE-EFDSNGKGGVDEDEFLRLMMS 175 >2JOJ-A nrPDB Length = 77 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + EQ +E KEAF LFD I Y + +RALG + + E+L ++ + +E Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTG--SIDYHELKVAMRALGFDVKKPEILELMNEYDRE--G 56 Query: 106 TKMMDFETFLPMLQHISKNKD 126 + F+ FL ++ KN+D Sbjct: 57 NGYIGFDDFLDIMTEKIKNRD 77 >4AOM-A nrPDB Length = 146 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 28/114 (24%), Positives = 56/114 (49%), Gaps = 11/114 (9%) Query: 81 RALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVF 140 R LG P+ + + + +EL + +E +L L +KD E+ ++ F Sbjct: 42 RKLGLAPSS------IDEKKIKELYGDNLTYEQYLEYLSICVHDKDN--VEELIKMFAHF 93 Query: 141 DKEGNGTVMGAELRHVLATLGERLTEDE-VEKLMAGQEDSNGCINYEAFVKHIM 193 D G + ++++++L T G+ LT+ E ++ L A + N I+Y+ F + I+ Sbjct: 94 DNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDN--IDYKLFCEDIL 145 >1H4B-A nrPDB Length = 84 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 2/54 (3%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 + FD G+G + AEL L TLG +T DEV+ +MA + D +G I+++ F Sbjct: 15 FKRFDANGDGKISAAELGEALKTLGS-ITPDEVKHMMAEIDTDGDGFISFQEFT 67 >3I5H-B nrPDB Length = 153 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 12/148 (8%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK-PRQ 101 +++ + Q++E KEAF + D+ + I D+ +LG+ P E+ +L + P Q Sbjct: 7 RVKLSQRQMQELKEAFTMIDQDR--DGFIGMEDLKDMFSSLGRVPPDDELNAMLKECPGQ 64 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 ++F FL + K T + +FD++G G + L+ +L +G Sbjct: 65 -------LNFTAFLTLFGE--KVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMG 115 Query: 162 ERLTEDEVEKLMAGQEDSNGCINYEAFV 189 + +++E++ + N NY V Sbjct: 116 DNFSKEEIKNVWKDAPLKNKQFNYNKMV 143 >2OPO-A nrPDB Length = 86 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 2/51 (3%) Query: 140 FDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 FD G+G + +EL L TLG +T DEV ++MA + D +G I+++ F Sbjct: 20 FDTNGDGKISSSELGDALKTLGS-VTPDEVRRMMAEIDTDGDGFISFDEFT 69 >5Z1Q-A nrPDB Length = 95 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 4/84 (4%) Query: 41 KIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPR 100 +++ E + EQ +E KEAF LFD I Y + +RALG + + E+L ++ + Sbjct: 16 RVRQELSEEQKQEIKEAFDLFDTNKTG--SIDYHELKVAMRALGFDVKKPEILELMNEYD 73 Query: 101 QEELNTKMMDFETFLPMLQHISKN 124 +E + F+ FL ++ KN Sbjct: 74 RE--GNGYIGFDDFLDIMTEKIKN 95 >2LV7-A nrPDB Length = 100 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E+ E +VFD++GNG + EL + +LG E E+E ++ + D +G +++E FV Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFV 95 Score = 32.7 bits (73), Expect = 0.11, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 4/70 (5%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 +++EE +EAF +FDR I+ + G +R+LG P + E+ ++ + + Sbjct: 33 DELEEIREAFKVFDRDGNG--FISKQELGTAMRSLGYMPNEVELEVIIQRLDMD--GDGQ 88 Query: 109 MDFETFLPML 118 +DFE F+ +L Sbjct: 89 VDFEEFVTLL 98 >2K7B-A nrPDB Length = 76 Score = 35.4 bits (80), Expect = 0.016, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 16/77 (20%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQC---GDVLRALGQNPTQAEVLRVLGKPRQEEL 104 PE+IEE +EAF FD+ K Y C G+ +R +G PT+ E++ + +++ Sbjct: 6 PEEIEELREAFREFDKD-----KDGYINCRDLGNCMRTMGYMPTEMELIEL-----SQQI 55 Query: 105 NTKM---MDFETFLPML 118 N + +DF+ F+ ++ Sbjct: 56 NMNLGGHVDFDDFVELM 72 >5E37-A nrPDB Length = 356 Score = 35.0 bits (79), Expect = 0.020, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 128 GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYE 186 GT ++ + DK GNGT+ EL + A+LG ++ +++ LM + D +G I + Sbjct: 108 GTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFP 167 Query: 187 AFV 189 F+ Sbjct: 168 EFL 170 Score = 28.9 bits (63), Expect = 1.6, Method: Compositional matrix adjust. Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 16/91 (17%) Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL--GE-------R 163 TF ++ SK K E+ ++ D +GNG + ELR++L ++ GE Sbjct: 15 TFEGLMDDASKAK----MEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHW 70 Query: 164 LTEDEVEKLMAGQEDSN--GCINYEAFVKHI 192 L EDE+E+ M Q D N G I++E F + I Sbjct: 71 LPEDELERCME-QYDVNKDGVISFEEFKQII 100 >5ZOR-A nrPDB Length = 149 Score = 34.7 bits (78), Expect = 0.027, Method: Compositional matrix adjust. Identities = 40/153 (26%), Positives = 73/153 (47%), Gaps = 17/153 (11%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPT-QAEVLRVLGKPRQEEL 104 T EQI +EAF LFD I + ++ LG + EV R + + Sbjct: 4 LTDEQI---REAFNLFDADGSG--AIDAEEMALAMKGLGFGDLPRDEVERTV-----RSM 53 Query: 105 NTK---MMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 NT ++++ F M++ KD+ E+ ++ ++FD + G + A L+ V LG Sbjct: 54 NTNANGLIEYGEFERMVKSRMAQKDS--PEEVLKAFQLFDLDKKGKISFANLKEVAKLLG 111 Query: 162 ERLTEDEVEKLMA-GQEDSNGCINYEAFVKHIM 193 E +D +++++A ED +G +++E F +M Sbjct: 112 ENPGDDVLQEMIAEADEDGDGEVSFEEFKSVMM 144 Score = 30.0 bits (66), Expect = 0.61, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG-ERLTEDEVEKLMAGQE-DSNGCINYE 186 T E E +FD +G+G + E+ + LG L DEVE+ + ++NG I Y Sbjct: 5 TDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYG 64 Query: 187 AFVKHIMS 194 F + + S Sbjct: 65 EFERMVKS 72 >5OTJ-D nrPDB Length = 110 Score = 34.7 bits (78), Expect = 0.029, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%) Query: 140 FDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKH 191 FD G+G + +EL L TLG + DEV+++MA + D +G I++ F+ Sbjct: 12 FDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNEFISF 63 >1S6I-A nrPDB Length = 188 Score = 34.7 bits (78), Expect = 0.029, Method: Compositional matrix adjust. Identities = 32/144 (22%), Positives = 67/144 (46%), Gaps = 10/144 (6%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + E+I KE F + D IT+ + D L+ +G ++E+ ++ ++ Sbjct: 4 LSEEEIGGLKELFKMIDTDNSG--TITFDELKDGLKRVGSELMESEIKDLMDAADIDKSG 61 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 T +D+ F+ H++K + E+ V FDK+G+G + E++ G L Sbjct: 62 T--IDYGEFIAATVHLNKLE---REENLVSAFSYFDKDGSGYITLDEIQQACKDFG--LD 114 Query: 166 EDEVEKLMAG-QEDSNGCINYEAF 188 + ++ ++ +D++G I+Y F Sbjct: 115 DIHIDDMIKEIDQDNDGQIDYGEF 138 Score = 32.7 bits (73), Expect = 0.091, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFV 189 ++ D + +GT+ EL+ L +G L E E++ LM A D +G I+Y F+ Sbjct: 16 FKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEFI 69 >2LVK-A nrPDB Length = 77 Score = 34.7 bits (78), Expect = 0.030, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 2/53 (3%) Query: 140 FDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKH 191 FD G+G + +EL L TLG + DEV+++MA + D +G I++ F+ Sbjct: 11 FDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNEFISF 62 >2AUC-A nrPDB Length = 126 Score = 34.3 bits (77), Expect = 0.037, Method: Compositional matrix adjust. Identities = 27/115 (23%), Positives = 52/115 (45%), Gaps = 13/115 (11%) Query: 81 RALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVF 140 R LG P+ + ++ +L + +E +L L ++D E+ ++ F Sbjct: 23 RKLGLAPSSTDEKKI------RDLYGDSLTYEQYLEYLTMCVHDRDN--MEELIKMFSHF 74 Query: 141 DKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG--QEDSNGCINYEAFVKHIM 193 D +G + +++++L T G+ LTE E + ED INY+ F + I+ Sbjct: 75 DNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSSEDR---INYKLFCEDIL 126 >1S6J-A nrPDB Length = 87 Score = 33.5 bits (75), Expect = 0.056, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFV 189 ++ D + +GT+ EL+ L +G L E E++ LM A D +G I+Y F+ Sbjct: 29 FKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEFI 82 >2K2I-A nrPDB Length = 79 Score = 33.1 bits (74), Expect = 0.082, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 37/63 (58%), Gaps = 1/63 (1%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEA 187 T E+ ++ ++FD + G + L+ V LGE LT++E+++++ D +G ++ + Sbjct: 9 TKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQE 68 Query: 188 FVK 190 F++ Sbjct: 69 FLR 71 >1ZMZ-A nrPDB Length = 98 Score = 33.1 bits (74), Expect = 0.085, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 5/79 (6%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E T EQ +E +EAF LFD I + +RALG P + E+ +++ + +E Sbjct: 24 ELTEEQKQEIREAFDLFDADGTG--TIDVKELKVAMRALGFEPKKEEIKKMISEIDKE-- 79 Query: 105 NTKMMDFETFLP-MLQHIS 122 T M+F FL M Q +S Sbjct: 80 GTGKMNFGDFLTVMTQKMS 98 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 135 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNGCINYEAFV 189 E +FD +G GT+ EL+ + LG ++E++K+++ ++ G +N+ F+ Sbjct: 35 EAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFL 90 >4N5X-A nrPDB Length = 199 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFVKHI 192 + D+ G+G V EL+ L LG L +D EK+ G + +G +++E F+K++ Sbjct: 28 FQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYL 84 Score = 26.6 bits (57), Expect = 7.8, Method: Compositional matrix adjust. Identities = 26/116 (22%), Positives = 49/116 (42%), Gaps = 22/116 (18%) Query: 91 EVLRVLGKPRQEELNTKM-----------MDFETFLPMLQ-HISKNKDTGTYEDFVEGLR 138 E LR LG P ++ K+ +DFE F+ L+ H K K + Sbjct: 46 EGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMK---------LAFK 96 Query: 139 VFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIM 193 DK +G + +E+ L TLG ++E + E ++ + D +++ + + + Sbjct: 97 SLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFL 152 >4GFT-A nrPDB Length = 69 Score = 32.0 bits (71), Expect = 0.15, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE-VEKLMAGQEDSNGCIN 184 D E+ ++ FD G + ++++++L T G+ LT+ E ++ L A + N I+ Sbjct: 2 DKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDN--ID 59 Query: 185 YEAFVKHIM 193 Y+ F + I+ Sbjct: 60 YKLFCEDIL 68 >4ZCV-A nrPDB Length = 165 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCINYEAFVKHI 192 + D+ G+G V EL+ L LG L +D EK+ G + +G +++E F+K++ Sbjct: 19 FQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYL 75 Score = 26.6 bits (57), Expect = 8.3, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 21/95 (22%) Query: 91 EVLRVLGKPRQEELNTKM-----------MDFETFLPMLQ-HISKNKDTGTYEDFVEGLR 138 E LR LG P ++ K+ +DFE F+ L+ H K K + Sbjct: 37 EGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMK---------LAFK 87 Query: 139 VFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM 173 DK +G + +E+ L TLG ++E + E ++ Sbjct: 88 SLDKNNDGKIEASEIVQSLQTLGLTISEQQAELIL 122 >2OS8-B nrPDB Length = 157 Score = 30.8 bits (68), Expect = 0.38, Method: Compositional matrix adjust. Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 10/157 (6%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 AS + + +QI+E KEAF + D+ + I ++ +LG+ P E+ +L K Sbjct: 6 ASGVLTKLPQKQIQEMKEAFTMIDQNRDGFIDIN--DLKEMFSSLGRTPDDKELTAML-K 62 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 LN F FL + K T + E +FD+ + ++ +L Sbjct: 63 EAPGPLN-----FTMFLSIFSD--KLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLE 115 Query: 159 TLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS 195 +G+ +DE+ G +Y FV I S Sbjct: 116 NMGDNFNKDEMRMTFKEAPVEGGKFDYVRFVAMIKGS 152 >1JUO-A nrPDB Length = 198 Score = 30.4 bits (67), Expect = 0.48, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 1/50 (2%) Query: 140 FDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFV 189 FD + +GTV EL+ L T+G RL+ V + A + +NG I ++ ++ Sbjct: 112 FDTDRSGTVDPQELQKALTTMGFRLSPQAVNSI-AKRYSTNGKITFDDYI 160 >5MRA-A nrPDB Length = 167 Score = 30.0 bits (66), Expect = 0.61, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 1/50 (2%) Query: 140 FDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFV 189 FD + +GTV EL+ L T+G RL+ V + A + +NG I ++ ++ Sbjct: 81 FDTDRSGTVDPQELQKALTTMGFRLSPQAVNSI-AKRYSTNGKITFDDYI 129 >3O4Y-A nrPDB Length = 196 Score = 30.0 bits (66), Expect = 0.62, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGER--LTEDEVEKL--MAGQEDSNG 181 RVFD + +G + AEL HVL +R +TE +V ++ M + D NG Sbjct: 131 FRVFDVDNDGEITTAELAHVLFNGNKRGNITERDVNQVKKMIREVDKNG 179 >1F4Q-A nrPDB Length = 165 Score = 28.9 bits (63), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 1/55 (1%) Query: 135 EGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFV 189 E D++G+GTV ELR + +G RL+ + ++ + NG I ++ +V Sbjct: 74 ENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVK-RYSKNGRIFFDDYV 127 >5HXV-A nrPDB Length = 190 Score = 28.9 bits (63), Expect = 1.5, Method: Compositional matrix adjust. Identities = 11/34 (32%), Positives = 16/34 (47%) Query: 65 PKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 P E +T+ CGD G NP A+ + G+ Sbjct: 32 PGGEYSVTWVNCGDFTSGKGWNPANAQTVTYSGE 65 >4BMK-A nrPDB Length = 442 Score = 28.5 bits (62), Expect = 2.0, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 18/39 (46%) Query: 1 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDA 39 + P+ +A A P A PA AP PER +FD Sbjct: 13 LVPRGSHMASTEAAAQPHALPADAPDIAPERDLLSKFDG 51 >4REW-A nrPDB Length = 540 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 26/56 (46%) Query: 86 NPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFD 141 N + L V+GK R+E N K+ + + Q IS D ++V G +FD Sbjct: 40 NRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFD 95 >4RED-A nrPDB Length = 351 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 26/56 (46%) Query: 86 NPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFD 141 N + L V+GK R+E N K+ + + Q IS D ++V G +FD Sbjct: 48 NRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFD 103 >4D1E-A nrPDB Length = 876 Score = 28.1 bits (61), Expect = 2.4, Method: Compositional matrix adjust. Identities = 14/59 (23%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +F FD+ NG + + R L ++G L E E ++M + + G + +++F+ Sbjct: 739 EFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFI 797 Score = 27.3 bits (59), Expect = 4.5, Method: Compositional matrix adjust. Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 13/115 (11%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKI-TYGQCGDVLRALGQNPTQAEVLRV--LGKPRQE 102 T EQ+ EF+ +F FDR M + C L ++G + +AE R+ L P + Sbjct: 732 ITQEQMNEFRASFNHFDRRKNGLMDHEDFRAC---LISMGYDLGEAEFARIMTLVDPNGQ 788 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 T F++F+ + + DT T E + R+ + ++ ELR L Sbjct: 789 GTVT----FQSFIDFM--TRETADTDTAEQVIASFRILASD-KPYILAEELRREL 836 >4CFH-A nrPDB Length = 493 Score = 28.1 bits (61), Expect = 2.4, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 26/56 (46%) Query: 86 NPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFD 141 N + L V+GK R+E N K+ + + Q IS D ++V G +FD Sbjct: 67 NRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFD 122 >2K7C-A nrPDB Length = 72 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/58 (25%), Positives = 34/58 (58%), Gaps = 2/58 (3%) Query: 135 EGLRVFDKEGNGTVMGAELRHVL-ATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 + R FD G+G + +ELR + LG ++ ++E+++ + + +G +++E FV+ Sbjct: 11 DAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVR 68 >1SJJ-A nrPDB Length = 863 Score = 28.1 bits (61), Expect = 2.8, Method: Compositional matrix adjust. Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 15/116 (12%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGD---VLRALGQNPTQAEVLRVLGKPRQE 102 + EQ+ EF+ +F FDR M C D L ++G N +AE R++ Sbjct: 719 ISQEQMNEFRASFNHFDRKKTGMM-----DCEDFRACLISMGYNMGEAEFARIMSI---- 769 Query: 103 ELNTKMMDFETFLPMLQHISK-NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 ++ M TF + +S+ DT T + + ++ + N + ELR L Sbjct: 770 -VDPNRMGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITVD-ELRREL 823 >3I82-A nrPDB Length = 227 Score = 27.7 bits (60), Expect = 3.2, Method: Compositional matrix adjust. Identities = 21/98 (21%), Positives = 39/98 (39%), Gaps = 3/98 (3%) Query: 64 TPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFL---PMLQH 120 T + +++ YG+ A G +PT EVL +LG P E+ + + Q Sbjct: 56 TKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMIAHIENGAAFQW 115 Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 + +DT V + G +G + +++A Sbjct: 116 ANDAQDTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVA 153 >5KOH-B nrPDB Length = 511 Score = 27.7 bits (60), Expect = 3.6, Method: Compositional matrix adjust. Identities = 34/140 (24%), Positives = 54/140 (38%), Gaps = 18/140 (12%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E+ + E+ ++F +T + G D+L+ L + + GKP +EL Sbjct: 291 EYCTPKTLEYCQSFG--QKTASFHYPLGIGATDDLLQKLSE---------ISGKPVPQEL 339 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYED--FVEGLRVFDKEGNGTVMGAELRHVLATLGE 162 + L Q K Y D FV G+ F E G E +H LAT G Sbjct: 340 EMERGRLVDALADSQAYLHGKTYAIYGDPDFVYGMARFILE-----TGGEPKHCLATNGS 394 Query: 163 RLTEDEVEKLMAGQEDSNGC 182 + E ++++L GC Sbjct: 395 KAWEAQMQELFDSSPFGVGC 414 >1GJY-A nrPDB Length = 167 Score = 27.3 bits (59), Expect = 4.0, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 140 FDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFV 189 FD + +GTV EL+ L T+G RL V + A + ++G I ++ ++ Sbjct: 81 FDSDRSGTVDPQELQKALTTMGFRLNPQTVNSI-AKRYSTSGKITFDDYI 129 >5GUP-v nrPDB Length = 453 Score = 26.6 bits (57), Expect = 6.4, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 14 KAAPKAAPAPAPPPEPERPKEVEF 37 K APKA + AP P +P+++EF Sbjct: 17 KVAPKALASAAPAGVPLQPQDLEF 40 >6DNC-BA nrPDB Length = 78 Score = 26.6 bits (57), Expect = 6.8, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 8/64 (12%) Query: 95 VLGKPRQEELNTKMMDFETFLPMLQ----HISKNKDTGTYEDFVEGLRVFDKEGNGTVMG 150 V G R LN FLP L + K T +G+RV DK+G TV+ Sbjct: 13 VTGNNRSHALNATK---RRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVL- 68 Query: 151 AELR 154 AELR Sbjct: 69 AELR 72 >4JWQ-A nrPDB Length = 199 Score = 26.6 bits (57), Expect = 7.1, Method: Compositional matrix adjust. Identities = 10/21 (47%), Positives = 14/21 (66%) Query: 137 LRVFDKEGNGTVMGAELRHVL 157 RVFD + +G + AEL H+L Sbjct: 134 FRVFDVDNDGEITTAELAHIL 154 >3K21-A nrPDB Length = 191 Score = 26.6 bits (57), Expect = 7.1, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 6/58 (10%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGER--LTEDEVEKL--MAGQEDSN--GCINYEAF 188 RVFD + +G + AEL H+L ++ +T+ +V ++ M D N G I++ F Sbjct: 128 FRVFDVDNDGEITTAELAHILYNGNKKGNITQRDVNRVKRMIRDVDKNNDGKIDFHEF 185 >2D8N-A nrPDB Length = 207 Score = 26.2 bits (56), Expect = 9.1, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 +DF+ ++ L + K T + ++D +GNGT+ E+ ++ + + +T ++ Sbjct: 88 LDFKEYVIALHMTTAGK---TNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPED 144 Query: 169 VEKLMAGQEDS 179 V KL+ E++ Sbjct: 145 V-KLLPDDENT 154 >3NCG-A nrPDB Length = 486 Score = 26.2 bits (56), Expect = 9.1, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 33/59 (55%), Gaps = 3/59 (5%) Query: 136 GLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN--GCINYEAFVKHI 192 ++FDK+G+G + EL + + + +E+E ++ Q D+N G +++ FV+ + Sbjct: 422 AFKMFDKDGSGKISTKELFKLFSQADSSIQMEELESIIE-QVDNNKDGEVDFNEFVEML 479 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5TBY-C nrPDB 256 4e-69 5UKG-A nrPDB 215 8e-57 3U0K-A nrPDB 213 4e-56 4IL1-A nrPDB 207 3e-54 4I2Y-A nrPDB 207 3e-54 4OY4-A nrPDB 204 2e-53 3EK4-A nrPDB 204 2e-53 6FSA-D nrPDB 203 3e-53 1W7I-B nrPDB 188 1e-48 3JAX-C nrPDB 187 2e-48 3WFN-B nrPDB 181 1e-46 6O20-F nrPDB 178 2e-45 5H53-C nrPDB 177 2e-45 2F2P-A nrPDB 177 3e-45 2N6A-A nrPDB 176 6e-45 4E53-A nrPDB 172 6e-44 6HCS-A nrPDB 170 3e-43 1CLM-A nrPDB 167 4e-42 2W4G-C nrPDB 166 6e-42 1GGZ-A nrPDB 165 9e-42 5A2H-A nrPDB 165 1e-41 5I0I-E nrPDB 164 2e-41 2LHI-A nrPDB 161 2e-40 1LKJ-A nrPDB 152 9e-38 2L1W-A nrPDB 151 1e-37 4DS7-A nrPDB 150 3e-37 2LMV-A nrPDB 147 2e-36 1SR6-C nrPDB 141 1e-34 1GGW-A nrPDB 136 6e-33 1TOP-A nrPDB 134 3e-32 3QRX-A nrPDB 133 4e-32 3I5I-C nrPDB 133 6e-32 2LC5-A nrPDB 133 6e-32 2LHH-A nrPDB 129 7e-31 2TN4-A nrPDB 129 7e-31 2BL0-B nrPDB 126 5e-30 5D43-A nrPDB 126 6e-30 3JBH-C nrPDB 126 6e-30 1DTL-A nrPDB 126 7e-30 2GGM-A nrPDB 124 4e-29 3FWC-A nrPDB 122 1e-28 1N2D-A nrPDB 121 2e-28 5TBY-E nrPDB 120 2e-28 2LAP-A nrPDB 120 3e-28 3KF9-A nrPDB 119 7e-28 3J04-B nrPDB 119 1e-27 2BL0-C nrPDB 117 2e-27 2OBH-A nrPDB 115 1e-26 3DTP-E nrPDB 114 3e-26 2JNF-A nrPDB 112 1e-25 1I84-U nrPDB 111 2e-25 5H53-B nrPDB 108 2e-24 5W1A-B nrPDB 106 8e-24 1O1A-B nrPDB 105 1e-23 2M29-A nrPDB 104 4e-23 5VT9-A nrPDB 100 6e-22 5B7X-A nrPDB 96 1e-20 2KN2-A nrPDB 95 2e-20 3IFK-A nrPDB 92 2e-19 2I08-A nrPDB 91 3e-19 1FW4-A nrPDB 91 4e-19 2M5E-A nrPDB 90 5e-19 2KZ2-A nrPDB 89 1e-18 5H7D-E nrPDB 89 2e-18 5COC-A nrPDB 89 2e-18 2RO8-A nrPDB 87 3e-18 2ROB-A nrPDB 86 7e-18 2RO9-A nrPDB 86 9e-18 5MWC-D nrPDB 84 4e-17 2N7L-C nrPDB 82 1e-16 5VLN-A nrPDB 82 2e-16 1F55-A nrPDB 81 2e-16 4Q57-A nrPDB 79 1e-15 2HF5-A nrPDB 77 3e-15 4GJF-A nrPDB 75 2e-14 1TRF-A nrPDB 74 4e-14 1TNP-A nrPDB 74 4e-14 2M8U-A nrPDB 74 5e-14 2KSZ-A nrPDB 73 7e-14 2B1U-A nrPDB 72 1e-13 2FCE-A nrPDB 72 1e-13 3TZ1-A nrPDB 70 7e-13 2M97-A nrPDB 69 1e-12 1OQP-A nrPDB 66 1e-11 1OZS-A nrPDB 61 4e-10 Sequences not found previously or not previously below threshold: 4WPX-A nrPDB 94 3e-20 3I5H-B nrPDB 92 1e-19 1S6I-A nrPDB 92 2e-19 2AAO-A nrPDB 89 2e-18 5ZOR-A nrPDB 86 1e-17 2OS8-B nrPDB 83 7e-17 3TS5-B nrPDB 81 2e-16 1B7T-Y nrPDB 79 1e-15 3LIJ-A nrPDB 79 1e-15 1DFK-Y nrPDB 78 3e-15 2EC6-B nrPDB 77 3e-15 2AMI-A nrPDB 77 3e-15 3HZT-A nrPDB 74 5e-14 3O4Y-A nrPDB 73 6e-14 1M39-A nrPDB 73 8e-14 3L19-A nrPDB 73 9e-14 3Q5I-A nrPDB 72 1e-13 4JWQ-A nrPDB 71 3e-13 4OCI-A nrPDB 70 5e-13 1ZMZ-A nrPDB 70 5e-13 4AOM-A nrPDB 69 9e-13 3K21-A nrPDB 69 1e-12 4RGJ-A nrPDB 69 1e-12 5JN2-A nrPDB 69 1e-12 4MVF-A nrPDB 69 1e-12 5Z1Q-A nrPDB 69 2e-12 2JOJ-A nrPDB 68 3e-12 3KHE-A nrPDB 67 5e-12 3NCG-A nrPDB 67 7e-12 2K2A-A nrPDB 66 1e-11 2K7C-A nrPDB 66 1e-11 2AUC-A nrPDB 65 1e-11 2LV7-A nrPDB 65 1e-11 3PM8-A nrPDB 65 1e-11 4ORC-B nrPDB 65 2e-11 4YZB-A nrPDB 65 2e-11 5E37-A nrPDB 64 3e-11 1JC2-A nrPDB 64 3e-11 2K2I-A nrPDB 64 4e-11 2K7B-A nrPDB 60 5e-10 5B8I-B nrPDB 60 7e-10 4D1E-A nrPDB 59 1e-09 1SJJ-A nrPDB 58 2e-09 1JUO-A nrPDB 56 1e-08 5MRA-A nrPDB 55 1e-08 4GFT-A nrPDB 55 1e-08 5OTJ-D nrPDB 55 2e-08 4ZCV-A nrPDB 55 2e-08 4N5X-A nrPDB 55 3e-08 2LVK-A nrPDB 54 5e-08 1Y1X-A nrPDB 54 6e-08 1C7W-A nrPDB 54 6e-08 1H4B-A nrPDB 53 7e-08 1GJY-A nrPDB 53 8e-08 1QXP-A nrPDB 53 9e-08 2OPO-A nrPDB 53 1e-07 2JNX-A nrPDB 51 3e-07 3AAJ-A nrPDB 51 3e-07 1F4Q-A nrPDB 51 3e-07 2BEC-A nrPDB 51 4e-07 5ZGM-A nrPDB 49 1e-06 2N8Y-A nrPDB 49 1e-06 2GGZ-A nrPDB 49 1e-06 1JF0-A nrPDB 49 1e-06 1S36-A nrPDB 49 1e-06 5PAL-A nrPDB 49 2e-06 2R2I-A nrPDB 48 2e-06 1KFX-S nrPDB 48 2e-06 2M1U-A nrPDB 48 3e-06 3E3R-A nrPDB 48 3e-06 2D58-A nrPDB 47 4e-06 1JFJ-A nrPDB 47 4e-06 1S6J-A nrPDB 47 6e-06 3DF0-A nrPDB 47 6e-06 2G2B-A nrPDB 47 6e-06 3KPX-A nrPDB 45 1e-05 2G9B-A nrPDB 45 1e-05 3BOW-B nrPDB 45 1e-05 5JOJ-A nrPDB 45 1e-05 5JOL-A nrPDB 45 2e-05 2L2E-A nrPDB 45 2e-05 1DGU-A nrPDB 45 2e-05 5I2L-A nrPDB 45 3e-05 2JUL-A nrPDB 45 3e-05 5CUY-A nrPDB 45 3e-05 2LM5-A nrPDB 44 3e-05 2E30-A nrPDB 44 4e-05 5T7C-A nrPDB 44 4e-05 1KFU-L nrPDB 44 4e-05 1V1G-A nrPDB 44 5e-05 1BJF-A nrPDB 43 7e-05 1WY9-A nrPDB 43 8e-05 2JU0-A nrPDB 43 9e-05 5C5V-A nrPDB 43 9e-05 2VTG-A nrPDB 43 1e-04 5XND-A nrPDB 43 1e-04 5M6C-E nrPDB 43 1e-04 1SL8-A nrPDB 43 1e-04 1TIZ-A nrPDB 42 1e-04 1NP8-A nrPDB 42 1e-04 4OKH-A nrPDB 42 1e-04 2KQY-A nrPDB 42 2e-04 2NA0-A nrPDB 42 2e-04 1UHK-A nrPDB 41 3e-04 5CUU-A nrPDB 41 3e-04 2KYF-A nrPDB 41 3e-04 4PAL-A nrPDB 41 3e-04 1RTP-1 nrPDB 41 4e-04 3PAT-A nrPDB 40 5e-04 1A75-A nrPDB 40 5e-04 2ZFD-A nrPDB 40 5e-04 1JBA-A nrPDB 40 6e-04 6EPA-A nrPDB 40 9e-04 4P5X-A nrPDB 39 0.001 5CPV-A nrPDB 39 0.001 2M7L-A nrPDB 39 0.001 1RK9-A nrPDB 39 0.001 1BU3-A nrPDB 39 0.001 2NLN-A nrPDB 39 0.002 1TTX-A nrPDB 39 0.002 1UHN-A nrPDB 39 0.002 1QX2-A nrPDB 39 0.002 3MSE-B nrPDB 39 0.002 5E1J-A nrPDB 38 0.002 5VE9-A nrPDB 38 0.003 5ZH6-A nrPDB 38 0.003 6DU8-A nrPDB 38 0.004 5YPX-A nrPDB 37 0.004 3H4S-E nrPDB 37 0.004 3DD4-A nrPDB 37 0.004 1YX7-A nrPDB 37 0.005 1S6C-A nrPDB 37 0.006 1G33-A nrPDB 37 0.007 1S1E-A nrPDB 36 0.011 2LCP-A nrPDB 36 0.011 1J7Q-A nrPDB 35 0.014 2E6W-A nrPDB 35 0.018 4MEW-A nrPDB 35 0.024 4I5L-B nrPDB 35 0.025 4P5W-A nrPDB 35 0.026 1NYA-A nrPDB 34 0.031 2Q4U-A nrPDB 34 0.031 1QS1-A nrPDB 34 0.036 3AKA-A nrPDB 34 0.037 2HPS-A nrPDB 34 0.038 2D8N-A nrPDB 34 0.039 1QS2-A nrPDB 34 0.054 2I94-A nrPDB 33 0.070 4NQG-A nrPDB 33 0.073 2MBX-A nrPDB 33 0.076 5XOP-A nrPDB 33 0.077 3LCP-C nrPDB 33 0.080 1IJ5-A nrPDB 33 0.098 4I5K-A nrPDB 32 0.13 5LN3-Z nrPDB 32 0.15 1ZFS-A nrPDB 32 0.18 4DDO-A nrPDB 32 0.21 4YGB-B nrPDB 31 0.26 2VRG-A nrPDB 31 0.32 2I18-A nrPDB 31 0.32 3A4U-B nrPDB 31 0.36 2JMM-A nrPDB 31 0.41 6R7Z-A nrPDB 31 0.41 4TX3-A nrPDB 30 0.44 6FSH-A nrPDB 30 0.45 2L0P-A nrPDB 30 0.81 5GAH-J nrPDB 30 0.84 2MA2-A nrPDB 30 0.96 6AGI-A nrPDB 29 1.0 5A1W-H nrPDB 29 1.1 2M7M-A nrPDB 29 1.2 3KRB-A nrPDB 29 1.3 6MI5-X nrPDB 29 1.9 1SP9-A nrPDB 29 1.9 2WCE-A nrPDB 29 2.0 3MC8-A nrPDB 29 2.1 6BY1-CI nrPDB 28 2.2 2HSZ-A nrPDB 28 2.5 4UPH-A nrPDB 28 2.9 4L9M-A nrPDB 28 3.2 6IIE-A nrPDB 28 3.6 4Z8X-A nrPDB 28 3.6 3FVB-A nrPDB 27 4.1 5W2O-A nrPDB 27 4.2 4NSC-A nrPDB 27 4.5 1QLS-A nrPDB 27 4.7 2NCO-A nrPDB 27 4.8 2DI4-A nrPDB 27 4.8 1CM8-A nrPDB 27 5.3 1I7F-A nrPDB 27 5.9 1CB1-A nrPDB 27 6.0 1C07-A nrPDB 27 6.2 3CS1-A nrPDB 27 7.9 1IRX-A nrPDB 26 8.8 >5TBY-C nrPDB Length = 195 Score = 256 bits (654), Expect = 4e-69, Method: Composition-based stats. Identities = 195/195 (100%), Positives = 195/195 (100%) Query: 1 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML 60 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML Sbjct: 1 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFML 60 Query: 61 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH 120 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH Sbjct: 61 FDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH 120 Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN 180 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN Sbjct: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN 180 Query: 181 GCINYEAFVKHIMSS 195 GCINYEAFVKHIMSS Sbjct: 181 GCINYEAFVKHIMSS 195 >5UKG-A nrPDB Length = 419 Score = 215 bits (548), Expect = 8e-57, Method: Composition-based stats. Identities = 70/173 (40%), Positives = 104/173 (60%), Gaps = 10/173 (5%) Query: 23 PAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRA 82 PA P ++ K + ++AS + T EQI EFKEAF LFD+ + IT + G V+R+ Sbjct: 255 PANGPVMQK-KTLGWEASNG--QLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRS 309 Query: 83 LGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDK 142 LGQNPT+AE+ ++ + + T DF FL M+ K T E+ E RVFDK Sbjct: 310 LGQNPTEAELQDMINEVDADGDGT--FDFPEFLTMMAR--KMSYRVTEEEIREAFRVFDK 365 Query: 143 EGNGTVMGAELRHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVKHIMS 194 +GNG + AELRHV+ LGE+LT++EV++++ D +G +NYE FV+ + + Sbjct: 366 DGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 418 >3U0K-A nrPDB Length = 442 Score = 213 bits (542), Expect = 4e-56, Method: Composition-based stats. Identities = 67/173 (38%), Positives = 106/173 (61%), Gaps = 10/173 (5%) Query: 23 PAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRA 82 P+ ++ K ++ ++ + T EQI EFKEAF LFD+ + IT + G V+R+ Sbjct: 278 PSNGAVMQK-KTKGWEPTR--DQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRS 332 Query: 83 LGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDK 142 LGQNPT+AE+ ++ + + T +DF FL M+ K DT + E+ E RVFDK Sbjct: 333 LGQNPTEAELQDMINEVDADGDGT--IDFPEFLIMMARKMK--DTDSEEEIREAFRVFDK 388 Query: 143 EGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 +GNG + AELRHV+ LGE+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 389 DGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 441 >4IL1-A nrPDB Length = 823 Score = 207 bits (526), Expect = 3e-54, Method: Composition-based stats. Identities = 64/154 (41%), Positives = 97/154 (62%), Gaps = 7/154 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 58 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ LG Sbjct: 59 D--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 114 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 115 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 Score = 69.7 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 61/155 (39%), Gaps = 16/155 (10%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 F ++I+ + F D ++ + L L QNP V+ + Sbjct: 170 SHFDADEIKRLGKRFKKLDLDNS--GSLSVEEFMS-LPELQQNPLVQRVIDIFDTD---- 222 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GE 162 +DF+ F+ + S D + R++D + +G + EL VL + G Sbjct: 223 -GNGEVDFKEFIEGVSQFSVKGDK--EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 279 Query: 163 RLTEDEVEK-----LMAGQEDSNGCINYEAFVKHI 192 L + ++++ ++ +D +G I++E F + Sbjct: 280 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 314 >4I2Y-A nrPDB Length = 421 Score = 207 bits (526), Expect = 3e-54, Method: Composition-based stats. Identities = 70/172 (40%), Positives = 106/172 (61%), Gaps = 10/172 (5%) Query: 25 PPPEP-ERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRAL 83 PP P + K + ++A+ + + T EQI EFKEAF LFD+ + IT + G V+R+L Sbjct: 257 PPDGPVMQKKTMGWEAT--RDQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSL 312 Query: 84 GQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKE 143 GQNPT+AE+ ++ + + T DF FL M+ K DT + E+ E RVFDK+ Sbjct: 313 GQNPTEAELQDMINEVDADGDGT--FDFPEFLTMMAR--KMNDTDSEEEIREAFRVFDKD 368 Query: 144 GNGTVMGAELRHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVKHIMS 194 GNG + AELRHV+ LGE+LT++EV++++ D +G +NYE FV+ + + Sbjct: 369 GNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 420 >4OY4-A nrPDB Length = 415 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 65/154 (42%), Positives = 97/154 (62%), Gaps = 7/154 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 8 GSDQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 65 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + T +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ LG Sbjct: 66 DGDGT--IDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 121 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 122 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 155 >3EK4-A nrPDB Length = 451 Score = 204 bits (518), Expect = 2e-53, Method: Composition-based stats. Identities = 64/155 (41%), Positives = 97/155 (62%), Gaps = 7/155 (4%) Query: 41 KIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPR 100 + + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 302 NTRDQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVD 359 Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ L Sbjct: 360 AD--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL 415 Query: 161 GERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 GE+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 416 GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 450 >6FSA-D nrPDB Length = 199 Score = 203 bits (517), Expect = 3e-53, Method: Composition-based stats. Identities = 174/199 (87%), Positives = 181/199 (90%), Gaps = 4/199 (2%) Query: 1 MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVE----FDASKIKIEFTPEQIEEFKE 56 MAPKKP+PKKD+AKA KAA APAP P P E FD SKIKIEFTPEQIEEFKE Sbjct: 1 MAPKKPDPKKDEAKAGAKAAAAPAPAPAPPPAPEPSKEPEFDPSKIKIEFTPEQIEEFKE 60 Query: 57 AFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLP 116 AF LFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP+QEELN+KMMDF+TFLP Sbjct: 61 AFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFDTFLP 120 Query: 117 MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQ 176 MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE+LTEDEVEKLMAGQ Sbjct: 121 MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKLTEDEVEKLMAGQ 180 Query: 177 EDSNGCINYEAFVKHIMSS 195 EDSNGCINYEAFVKHIM+ Sbjct: 181 EDSNGCINYEAFVKHIMAG 199 >1W7I-B nrPDB Length = 151 Score = 188 bits (477), Expect = 1e-48, Method: Composition-based stats. Identities = 106/151 (70%), Positives = 128/151 (84%), Gaps = 2/151 (1%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 IEF +Q+EEFKEAF LFDR + KI Y QCGDV+RALGQNPT AEVL+VLG P+ +E Sbjct: 2 IEFNKDQLEEFKEAFELFDRV--GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDE 59 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 L ++ +DFETFLPMLQ ++KN+ GTYED++EG RVFDKEGNG VMGAELRHVL TLGE+ Sbjct: 60 LKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEK 119 Query: 164 LTEDEVEKLMAGQEDSNGCINYEAFVKHIMS 194 +TE+EVE ++AG EDSNGCINYEAF+KHI+S Sbjct: 120 MTEEEVETVLAGHEDSNGCINYEAFLKHILS 150 >3JAX-C nrPDB Length = 151 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 102/151 (67%), Positives = 125/151 (82%), Gaps = 2/151 (1%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 +F+ EQ EFKEAF LFDRT + KI Y QCGDV+RALGQNPT AEV++VLG P+ +E+ Sbjct: 3 DFSEEQTAEFKEAFQLFDRT--GDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEM 60 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 N K + FE FLPM+Q I+KNKD G +ED+VEGLRVFDKEGNGTVMGAE+RHVL TLGE++ Sbjct: 61 NLKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKM 120 Query: 165 TEDEVEKLMAGQEDSNGCINYEAFVKHIMSS 195 TE+EVE+L+AG EDSNGCINYE V+ ++S Sbjct: 121 TEEEVEQLVAGHEDSNGCINYEELVRMVLSG 151 >3WFN-B nrPDB Length = 182 Score = 181 bits (460), Expect = 1e-46, Method: Composition-based stats. Identities = 64/154 (41%), Positives = 97/154 (62%), Gaps = 7/154 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 7 MADQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 64 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ LG Sbjct: 65 D--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 120 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 121 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 154 >6O20-F nrPDB Length = 169 Score = 178 bits (451), Expect = 2e-45, Method: Composition-based stats. Identities = 65/157 (41%), Positives = 98/157 (62%), Gaps = 7/157 (4%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 S + + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 18 GSHMADQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINE 75 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 + +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ Sbjct: 76 VDAD--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 131 Query: 159 TLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 LGE+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 132 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 168 >5H53-C nrPDB Length = 153 Score = 177 bits (449), Expect = 2e-45, Method: Composition-based stats. Identities = 118/153 (77%), Positives = 130/153 (84%), Gaps = 2/153 (1%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 IKIEF+ EQ +EFKEAF+L+DRT + KIT Q GDVLRALG NPT AEV +VLG P Sbjct: 1 IKIEFSKEQQDEFKEAFLLYDRT--GDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSN 58 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 EE+N K ++FE FLPMLQ IS NKD GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG Sbjct: 59 EEMNAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 118 Query: 162 ERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMS 194 E++ E+EVE LMAGQEDSNGCINYEAFVKHIMS Sbjct: 119 EKMKEEEVEALMAGQEDSNGCINYEAFVKHIMS 151 >2F2P-A nrPDB Length = 179 Score = 177 bits (449), Expect = 3e-45, Method: Composition-based stats. Identities = 64/154 (41%), Positives = 97/154 (62%), Gaps = 7/154 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 58 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ LG Sbjct: 59 D--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 114 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 115 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 >2N6A-A nrPDB Length = 173 Score = 176 bits (446), Expect = 6e-45, Method: Composition-based stats. Identities = 64/150 (42%), Positives = 95/150 (63%), Gaps = 7/150 (4%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 7 TEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD--GN 62 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ LGE+LT+ Sbjct: 63 GTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 120 Query: 167 DEVEKLMAGQE-DSNGCINYEAFVKHIMSS 195 +EV++++ + D +G +NYE FV+ + + Sbjct: 121 EEVDEMIREADIDGDGQVNYEEFVQMMTGA 150 Score = 49.7 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 4/86 (4%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 + + EE +EAF +FD+ I+ + V+ LG+ T EV ++ + + Sbjct: 76 RKMKDTDSEEEIREAFRVFDKD--GNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID 133 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTG 128 +++E F+ M+ S +G Sbjct: 134 --GDGQVNYEEFVQMMTGASTAAGSG 157 >4E53-A nrPDB Length = 185 Score = 172 bits (437), Expect = 6e-44, Method: Composition-based stats. Identities = 64/152 (42%), Positives = 96/152 (63%), Gaps = 7/152 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 8 MADQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 65 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ LG Sbjct: 66 D--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 121 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 E+LT++EV++++ + D +G +NYE FV+ + Sbjct: 122 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 >6HCS-A nrPDB Length = 167 Score = 170 bits (431), Expect = 3e-43, Method: Composition-based stats. Identities = 63/154 (40%), Positives = 96/154 (62%), Gaps = 7/154 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDA 58 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + +DF FL M+ K DT + E+ E RVFDK+GNG + AELRH + LG Sbjct: 59 D--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLG 114 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E+LT++EV++++ + D +G +NYE FV+ + + Sbjct: 115 EKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 >1CLM-A nrPDB Length = 148 Score = 167 bits (422), Expect = 4e-42, Method: Composition-based stats. Identities = 64/151 (42%), Positives = 98/151 (64%), Gaps = 7/151 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 E T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 3 ELTEEQIAEFKEAFALFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD-- 58 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 +DF FL ++ K +D + E+ +E +VFD++GNG + AELRHV+ LGE+L Sbjct: 59 GNGTIDFPEFLSLMARKMKEQD--SEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKL 116 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 T+DEV++++ + D +G INYE FV+ ++S Sbjct: 117 TDDEVDEMIREADIDGDGHINYEEFVRMMVS 147 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 4/76 (5%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 + + EE EAF +FDR I+ + V+ LG+ T EV ++ + + Sbjct: 74 RKMKEQDSEEELIEAFKVFDRD--GNGLISAAELRHVMTNLGEKLTDDEVDEMIREADID 131 Query: 103 ELNTKMMDFETFLPML 118 +++E F+ M+ Sbjct: 132 --GDGHINYEEFVRMM 145 >2W4G-C nrPDB Length = 145 Score = 166 bits (420), Expect = 6e-42, Method: Composition-based stats. Identities = 106/146 (72%), Positives = 125/146 (85%), Gaps = 2/146 (1%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 ++I +FKEAF+LFDRT + KIT Q GD++RALGQNPT AE+ ++LG P +EE+N K Sbjct: 1 DEINDFKEAFLLFDRT--GDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKK 58 Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 + FE FLPMLQ + NKD GT+EDFVEGLRVFDKEGNGTVMGAELRHVLATLGE++TE+E Sbjct: 59 ITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEE 118 Query: 169 VEKLMAGQEDSNGCINYEAFVKHIMS 194 VE+LM GQEDSNGCINYEAFVKHIMS Sbjct: 119 VEELMKGQEDSNGCINYEAFVKHIMS 144 >1GGZ-A nrPDB Length = 148 Score = 165 bits (418), Expect = 9e-42, Method: Composition-based stats. Identities = 64/151 (42%), Positives = 97/151 (64%), Gaps = 7/151 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ+ EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + ++ Sbjct: 3 QLTEEQVTEFKEAFSLFDKD--GDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRD-- 58 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 +DF FL M+ K DT E+ E RVFDK+GNG V AELRHV+ LGE+L Sbjct: 59 GNGTVDFPEFLGMMARKMK--DTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKL 116 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 +++EV++++ + D +G +NYE FV+ ++S Sbjct: 117 SDEEVDEMIRAADTDGDGQVNYEEFVRVLVS 147 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 36/83 (43%), Gaps = 4/83 (4%) Query: 36 EFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRV 95 EF + + EE +EAF +FD+ ++ + V+ LG+ + EV + Sbjct: 67 EFLGMMARKMKDTDNEEEIREAFRVFDKD--GNGFVSAAELRHVMTRLGEKLSDEEVDEM 124 Query: 96 LGKPRQEELNTKMMDFETFLPML 118 + + +++E F+ +L Sbjct: 125 IRAADTD--GDGQVNYEEFVRVL 145 >5A2H-A nrPDB Length = 149 Score = 165 bits (418), Expect = 1e-41, Method: Composition-based stats. Identities = 64/154 (41%), Positives = 97/154 (62%), Gaps = 7/154 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + + T +QI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + Sbjct: 1 MADQLTDDQISEFKEAFSLFDKD--GDGCITTKELGTVMRSLGQNPTEAELQDMINEVDA 58 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + +DF FL ++ K DT + E+ E RVFDK+ NG + AELRHV+ LG Sbjct: 59 D--GNGTIDFPEFLNLMARKMK--DTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLG 114 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E+LT++EV++++ + D +G INYE FVK +M+ Sbjct: 115 EKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 148 >5I0I-E nrPDB Length = 145 Score = 164 bits (416), Expect = 2e-41, Method: Composition-based stats. Identities = 63/150 (42%), Positives = 94/150 (62%), Gaps = 7/150 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF L D+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 2 QLTEEQIAEFKEAFSLADKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD-- 57 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 +DF FL M+ K DT + E+ E RVFDK+GNG + AELRHV+ LGE+L Sbjct: 58 GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKL 115 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIM 193 T++EV++++ + D +G +NYE FV+ + Sbjct: 116 TDEEVDEMIREADIDGDGQVNYEEFVQMMT 145 >2LHI-A nrPDB Length = 176 Score = 161 bits (407), Expect = 2e-40, Method: Composition-based stats. Identities = 51/154 (33%), Positives = 86/154 (55%), Gaps = 6/154 (3%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + Sbjct: 1 GSSNLTEEQIAEFKEAFALFDKDNN--GSISSSELATVMRSLGLSPSEAEVNDLMNEIDV 58 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + ++F FL ++ K+ D + ++ +E +VFDK G+G + AEL+HVL ++G Sbjct: 59 D--GNHQIEFSEFLALMSRQLKSND--SEQELLEAFKVFDKNGDGLISAAELKHVLTSIG 114 Query: 162 ERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS 195 E+LT+ EV+ ++ D +G IN + F + Sbjct: 115 EKLTDAEVDDMLREVSDGSGEINIQQFAALLSKG 148 >1LKJ-A nrPDB Length = 146 Score = 152 bits (384), Expect = 9e-38, Method: Composition-based stats. Identities = 51/147 (34%), Positives = 86/147 (58%), Gaps = 6/147 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 4 LTEEQIAEFKEAFALFDKDNN--GSISSSELATVMRSLGLSPSEAEVNDLMNEIDVD--G 59 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL ++ K+ D + ++ +E +VFDK G+G + AEL+HVL ++GE+LT Sbjct: 60 NHQIEFSEFLALMSRQLKSND--SEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 117 Query: 166 EDEVEKLMAGQEDSNGCINYEAFVKHI 192 + EV+ ++ D +G IN + F + Sbjct: 118 DAEVDDMLREVSDGSGEINIQQFAALL 144 >2L1W-A nrPDB Length = 149 Score = 151 bits (382), Expect = 1e-37, Method: Composition-based stats. Identities = 57/150 (38%), Positives = 92/150 (61%), Gaps = 7/150 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + EQI +FKEAF LFD+ + IT + V+R+L QNPT+ E+ ++ + + Sbjct: 4 LSEEQIVDFKEAFGLFDKD--GDGCITVEELATVIRSLDQNPTEEELQDMISEVDAD--G 59 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F+ FL ++ K DT E+ E +VFDK+ NG + +ELRHV+ LGE+LT Sbjct: 60 NGTIEFDEFLSLMAKKVK--DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLT 117 Query: 166 EDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 ++EVE+++ + D +G +NYE FVK +M+ Sbjct: 118 DEEVEQMIKEADLDGDGQVNYEEFVKMMMT 147 >4DS7-A nrPDB Length = 147 Score = 150 bits (379), Expect = 3e-37, Method: Composition-based stats. Identities = 51/147 (34%), Positives = 86/147 (58%), Gaps = 6/147 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 5 LTEEQIAEFKEAFALFDKDNS--GSISASELATVMRSLGLSPSEAEVADLMNEIDVD--G 60 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL ++ K D + ++ +E +VFDK G+G + AEL+HVL ++GE+LT Sbjct: 61 NHAIEFSEFLALMSRQLKCND--SEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 118 Query: 166 EDEVEKLMAGQEDSNGCINYEAFVKHI 192 + EV++++ D +G IN + F + Sbjct: 119 DAEVDEMLREVSDGSGEINIKQFAALL 145 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DS 179 +S+N +F E +FDK+ +G++ +EL V+ +LG +E EV LM + D Sbjct: 1 MSQNLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDG 60 Query: 180 NGCINYEAFVKHI 192 N I + F+ + Sbjct: 61 NHAIEFSEFLALM 73 >2LMV-A nrPDB Length = 148 Score = 147 bits (372), Expect = 2e-36, Method: Composition-based stats. Identities = 55/150 (36%), Positives = 92/150 (61%), Gaps = 7/150 (4%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 E T EQI EFK+AF+ FD+ + KI + G ++R LGQNPT+AE+ ++ + E Sbjct: 2 SELTEEQIAEFKDAFVQFDK--EGTGKIATRELGTLMRTLGQNPTEAELQDLIAE--AEN 57 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 N ++F F ++ ++T T E+ E ++FD++G+G + AELR V+ LGE+ Sbjct: 58 NNNGQLNFTEFCGIMAKQM--RETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEK 115 Query: 164 LTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 +T++E+++++ + D +G INYE FV I Sbjct: 116 VTDEEIDEMIREADFDGDGMINYEEFVWMI 145 Score = 56.6 bits (135), Expect = 7e-09, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSN 180 +F + FDKEG G + EL ++ TLG+ TE E++ L+A E ++N Sbjct: 1 MSELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNN 60 Query: 181 GCINYEAFVKHI 192 G +N+ F + Sbjct: 61 GQLNFTEFCGIM 72 >1SR6-C nrPDB Length = 156 Score = 141 bits (356), Expect = 1e-34, Method: Composition-based stats. Identities = 55/154 (35%), Positives = 90/154 (58%), Gaps = 7/154 (4%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + + ++I++ K+ F LFD + + + GDV R LG NP +V V G + E Sbjct: 2 KLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFAVGGTHKMGE- 60 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERL 164 K + FE FLP + + + + GT+ D++E + FD+EG G + GAELRHVL LGERL Sbjct: 61 --KSLPFEEFLPAYEGLM-DCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERL 117 Query: 165 TEDEVEKLMAGQE---DSNGCINYEAFVKHIMSS 195 ++++V++++ + D G + YE FVK +M+ Sbjct: 118 SDEDVDEIIKLTDLQEDLEGNVKYEDFVKKVMAG 151 >1GGW-A nrPDB Length = 140 Score = 136 bits (342), Expect = 6e-33, Method: Composition-based stats. Identities = 54/142 (38%), Positives = 83/142 (58%), Gaps = 8/142 (5%) Query: 54 FKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFET 113 +K+AF LFDR +I GD+LRA GQNPT AE+ + E +D E Sbjct: 7 YKQAFSLFDRH--GTGRIPKTSIGDLLRACGQNPTLAEITEI------ESTLPAEVDMEQ 58 Query: 114 FLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM 173 FL +L + G E+FV+G +VFDK+ G + ELR+VL +LGE+L+ +E+++L+ Sbjct: 59 FLQVLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELL 118 Query: 174 AGQEDSNGCINYEAFVKHIMSS 195 G +G +NY FV+ I+++ Sbjct: 119 KGVPVKDGMVNYHDFVQMILAN 140 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 5/67 (7%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EEF + F +FD+ I G+ VL +LG+ + E+ +L + M+++ Sbjct: 76 EEFVKGFQVFDKDAT--GMIGVGELRYVLTSLGEKLSNEEMDELLKGV---PVKDGMVNY 130 Query: 112 ETFLPML 118 F+ M+ Sbjct: 131 HDFVQMI 137 >1TOP-A nrPDB Length = 162 Score = 134 bits (336), Expect = 3e-32, Method: Composition-based stats. Identities = 48/157 (30%), Positives = 86/157 (54%), Gaps = 6/157 (3%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 ++ + + E I EFK AF +FD + I+ + G V+R LGQNPT+ E+ ++ Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGD--ISTKELGTVMRMLGQNPTKEELDAIIE 63 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTG-TYEDFVEGLRVFDKEGNGTVMGAELRHV 156 + ++ + +DFE FL M+ K G + E+ R+FDK +G + EL + Sbjct: 64 EVDED--GSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEI 121 Query: 157 LATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 L GE +TE+++E LM + +++G I+++ F+K + Sbjct: 122 LRATGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMM 158 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNGCIN 184 +F +FD +G G + EL V+ LG+ T++E++ ++ ED +G I+ Sbjct: 15 SEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTID 74 Query: 185 YEAFVKHIM 193 +E F+ ++ Sbjct: 75 FEEFLVMMV 83 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 37/68 (54%), Gaps = 4/68 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE F +FD+ + I + G++LRA G++ T+ ++ ++ ++ N +DF Sbjct: 96 EELANCFRIFDKN--ADGFIDIEELGEILRATGEHVTEEDIEDLM--KDSDKNNDGRIDF 151 Query: 112 ETFLPMLQ 119 + FL M++ Sbjct: 152 DEFLKMME 159 >3QRX-A nrPDB Length = 169 Score = 133 bits (335), Expect = 4e-32, Method: Composition-based stats. Identities = 45/156 (28%), Positives = 86/156 (55%), Gaps = 7/156 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D K ++ T EQ +E +EAF LFD I + +RALG P + E+ +++ Sbjct: 14 DQKKGRVGLTEEQKQEIREAFDLFDTD--GSGTIDAKELKVAMRALGFEPKKEEIKKMIS 71 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 + ++ + +DFE FL M+ +D + E+ ++ R+FD + +GT+ +LR V Sbjct: 72 EIDKD--GSGTIDFEEFLTMMTAKMGERD--SREEILKAFRLFDDDNSGTITIKDLRRVA 127 Query: 158 ATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 LGE LTE+E+++++A + + + I+ + F++ + Sbjct: 128 KELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIM 163 Score = 59.3 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 ++ E +FD +G+GT+ EL+ + LG ++E++K+++ + D +G I++ Sbjct: 24 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDF 83 Query: 186 EAFVKHIMS 194 E F+ + + Sbjct: 84 EEFLTMMTA 92 >3I5I-C nrPDB Length = 159 Score = 133 bits (334), Expect = 6e-32, Method: Composition-based stats. Identities = 53/155 (34%), Positives = 84/155 (54%), Gaps = 6/155 (3%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 + T ++IEE +E F LFD + + + GD+LR LG NPT+A+V + G + E Sbjct: 1 SQLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQHGGTKKMGE 60 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 K E LP+ + +S ++F+E + FD+EG G + AE+R+VL LGER Sbjct: 61 KAYK---LEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLGER 117 Query: 164 LTEDEVEKLMAGQE---DSNGCINYEAFVKHIMSS 195 +TED+ + + D +G I YE +K +M+ Sbjct: 118 ITEDQCNDIFTFCDIREDIDGNIKYEDLMKKVMAG 152 >2LC5-A nrPDB Length = 151 Score = 133 bits (334), Expect = 6e-32, Method: Composition-based stats. Identities = 61/155 (39%), Positives = 91/155 (58%), Gaps = 6/155 (3%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP 99 S+ K T E+ +E+KEAF LFD+ + K+T + G V+RALG NPT+ ++ ++ Sbjct: 2 SEQKKVLTAEEQQEYKEAFQLFDKDN--DNKLTAEELGTVMRALGANPTKQKISEIVKDY 59 Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 ++ N+ D ETFL ++ + D+ ED + +FDKE NG + +EL+HVL T Sbjct: 60 DKD--NSGKFDQETFLTIMLEYGQEVDST--EDIKKAFEIFDKEKNGYISASELKHVLTT 115 Query: 160 LGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMS 194 LGE+LTE EV+ L+ G IN + FVK I S Sbjct: 116 LGEKLTEQEVDDLLKEIGVEEGLINVDDFVKLITS 150 Score = 52.4 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 + K +++ E ++FDK+ + + EL V+ LG T+ ++ +++ + Sbjct: 1 MSEQKKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYD 60 Query: 178 -DSNGCINYEAFVKHIM 193 D++G + E F+ ++ Sbjct: 61 KDNSGKFDQETFLTIML 77 >2LHH-A nrPDB Length = 128 Score = 129 bits (324), Expect = 7e-31, Method: Composition-based stats. Identities = 46/125 (36%), Positives = 76/125 (60%), Gaps = 6/125 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 4 LTEEQIAEFKEAFALFDKDNN--GSISSSELATVMRSLGLSPSEAEVNDLMNEIDVD--G 59 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL ++ K+ D + ++ +E +VFDK G+G + AEL+HVL ++GE+LT Sbjct: 60 NHQIEFSEFLALMSRQLKSND--SEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLT 117 Query: 166 EDEVE 170 + E+E Sbjct: 118 DAELE 122 Score = 60.1 bits (144), Expect = 6e-10, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 +F E +FDK+ NG++ +EL V+ +LG +E EV LM + D N I + Sbjct: 6 EEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEF 65 Query: 186 EAFVKHI 192 F+ + Sbjct: 66 SEFLALM 72 >2TN4-A nrPDB Length = 159 Score = 129 bits (324), Expect = 7e-31, Method: Composition-based stats. Identities = 47/157 (29%), Positives = 86/157 (54%), Gaps = 6/157 (3%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 ++ + + E I EFK AF +FD + I+ + G V+R LGQ PT+ E+ ++ Sbjct: 3 QQAEARSYLSEEMIAEFKAAFDMFDADGGGD--ISVKELGTVMRMLGQTPTKEELDAIIE 60 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTG-TYEDFVEGLRVFDKEGNGTVMGAELRHV 156 + ++ + +DFE FL M+ K G + E+ E R+FD+ +G + EL + Sbjct: 61 EVDED--GSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEI 118 Query: 157 LATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVKHI 192 GE +T++E+E LM G ++++G I+++ F+K + Sbjct: 119 FRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNGCIN 184 +F +FD +G G + EL V+ LG+ T++E++ ++ ED +G I+ Sbjct: 12 SEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTID 71 Query: 185 YEAFVKHIM 193 +E F+ ++ Sbjct: 72 FEEFLVMMV 80 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 4/68 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE E F +FDR + I + ++ RA G++ T E+ ++ ++ N +DF Sbjct: 93 EELAELFRIFDRN--ADGYIDAEELAEIFRASGEHVTDEEIESLM--KDGDKNNDGRIDF 148 Query: 112 ETFLPMLQ 119 + FL M++ Sbjct: 149 DEFLKMME 156 >2BL0-B nrPDB Length = 145 Score = 126 bits (317), Expect = 5e-30, Method: Composition-based stats. Identities = 52/145 (35%), Positives = 82/145 (56%), Gaps = 9/145 (6%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 ++ +E F +FD+ + K++ + G LR+LG+NPT AE+ + + +LN K D Sbjct: 5 DQIQECFQIFDKDN--DGKVSIEELGSALRSLGKNPTNAELNTI-----KGQLNAKEFDL 57 Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 TF + + K T ++ ++ R DKEGNGT+ AELR +L LG+ LT EVE+ Sbjct: 58 ATFKTVYRKPIKTP-TEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEE 116 Query: 172 LMAGQED-SNGCINYEAFVKHIMSS 195 LM +G INYE+FV +++ Sbjct: 117 LMKEVSVSGDGAINYESFVDMLVTG 141 >5D43-A nrPDB Length = 178 Score = 126 bits (317), Expect = 6e-30, Method: Composition-based stats. Identities = 45/151 (29%), Positives = 79/151 (52%), Gaps = 7/151 (4%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 K E T +Q +E +EAF LFD I + +RALG P + E+ +++ + +E Sbjct: 22 KPELTEDQKQEVREAFDLFD--SDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKE 79 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 162 T + F FL ++ KD T E+ ++ R+FD + G + L+ V LGE Sbjct: 80 --ATGKISFNDFLAVMTQKMAEKD--TKEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 Query: 163 RLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 LT++E+++++ + D +G +N E F+K + Sbjct: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 >3JBH-C nrPDB Length = 156 Score = 126 bits (316), Expect = 6e-30, Method: Composition-based stats. Identities = 63/153 (41%), Positives = 92/153 (60%), Gaps = 6/153 (3%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 + ++E+ +E F ++D + E KI GD+LR+L PT A V + G ++ Sbjct: 2 ADLKAAEVEKAREHFEIYDW--EGEGKIDARDLGDLLRSLDCKPTLAMVKKNGG---SDK 56 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 K + E FLP+ I K K+ GT EDF+EGL+V+DK NGT++ AEL HVL +LGER Sbjct: 57 RGEKKLTLEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGER 116 Query: 164 LTEDEVEKLMA-GQEDSNGCINYEAFVKHIMSS 195 LT+ E E++M ED +G + YE FVK I++ Sbjct: 117 LTDIECEEIMRVCDEDDDGFLKYEPFVKTIIAG 149 >1DTL-A nrPDB Length = 161 Score = 126 bits (316), Expect = 7e-30, Method: Composition-based stats. Identities = 49/150 (32%), Positives = 87/150 (58%), Gaps = 5/150 (3%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 11 QLTEEQKNEFKAAFDIFVL-GAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDED-- 67 Query: 105 NTKMMDFETFLPMLQHISKNKDTG-TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 + +DF+ FL M+ K+ G + E+ + R+FDK +G + EL+ +L GE Sbjct: 68 GSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGET 127 Query: 164 LTEDEVEKLMA-GQEDSNGCINYEAFVKHI 192 +TED++E+LM G ++++G I+Y+ F++ + Sbjct: 128 ITEDDIEELMKDGDKNNDGRIDYDEFLEFM 157 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 117 MLQHISKNKDTGTYEDFVEGLRVFD-KEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG 175 + + + +F +F +G++ EL V+ LG+ T +E+++++ Sbjct: 4 IYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDE 63 Query: 176 -QEDSNGCINYEAFVKHIMSS 195 ED +G ++++ F+ ++ S Sbjct: 64 VDEDGSGTVDFDEFLVMMVRS 84 >2GGM-A nrPDB Length = 172 Score = 124 bits (310), Expect = 4e-29, Method: Composition-based stats. Identities = 43/151 (28%), Positives = 80/151 (52%), Gaps = 7/151 (4%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 K E T EQ +E +EAF LFD I + +RALG P + E+ +++ + +E Sbjct: 22 KPELTEEQKQEIREAFDLFDAD--GTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKE 79 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 162 T M+F FL ++ KD T E+ ++ ++FD + G + L+ V LGE Sbjct: 80 --GTGKMNFGDFLTVMTQKMSEKD--TKEEILKAFKLFDDDETGKISFKNLKRVAKELGE 135 Query: 163 RLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 LT++E+++++ + D +G ++ + F++ + Sbjct: 136 NLTDEELQEMIDEADRDGDGEVSEQEFLRIM 166 >3FWC-A nrPDB Length = 161 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 7/149 (4%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + E EQ +E EAF LFD + + Y + ++ALG + E+L ++ + Sbjct: 13 LNSELLEEQKQEIYEAFSLFDMNN--DGFLDYHELKVAMKALGFELPKREILDLIDEYDS 70 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 E +M ++ F ++ +D ++ ++FD + G + LR V LG Sbjct: 71 E--GRHLMKYDDFYIVMGEKILKRDP--LDEIKRAFQLFDDDHTGKISIKNLRRVAKELG 126 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E LT++E+ ++ + D +G IN F+ Sbjct: 127 ETLTDEELRAMIEEFDLDGDGEINENEFI 155 >1N2D-A nrPDB Length = 148 Score = 121 bits (303), Expect = 2e-28, Method: Composition-based stats. Identities = 51/143 (35%), Positives = 79/143 (55%), Gaps = 7/143 (4%) Query: 55 KEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETF 114 K+ F LFD+ K + I GD LRA+G NPT V ++ + + + Sbjct: 7 KDIFTLFDK--KGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLR-DASSLTLDQI 63 Query: 115 LPMLQHISKNKDTGTY---EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 +++ K D T EDFV+ +VFDKE G V +LR++L LGE+LT+ EV++ Sbjct: 64 TGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDE 123 Query: 172 LMAGQE-DSNGCINYEAFVKHIM 193 L+ G E DSNG I+Y+ F++ ++ Sbjct: 124 LLKGVEVDSNGEIDYKKFIEDVL 146 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 4/75 (5%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 T + E+F +AF +FD+ + K++ G +L LG+ T AEV +L + + Sbjct: 78 TKAKTEDFVKAFQVFDK--ESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVD--SN 133 Query: 107 KMMDFETFLPMLQHI 121 +D++ F+ + Sbjct: 134 GEIDYKKFIEDVLRQ 148 >5TBY-E nrPDB Length = 166 Score = 120 bits (302), Expect = 2e-28, Method: Composition-based stats. Identities = 46/165 (27%), Positives = 70/165 (42%), Gaps = 10/165 (6%) Query: 32 PKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAE 91 K S + F QI+EFKEAF + D+ + I D ALG+ + E Sbjct: 7 KKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNR--DGFIDKNDLRDTFAALGRVNVKNE 64 Query: 92 VLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 + + K +N F FL M K D E + +VFD EG G + Sbjct: 65 EIDEMIKEAPGPIN-----FTVFLTMFGEKLKGADP--EETILNAFKVFDPEGKGVLKAD 117 Query: 152 ELRHVLATLGERLTEDEVEKLMAG-QEDSNGCINYEAFVKHIMSS 195 +R +L T ER +++EV+++ A D G ++Y+ V I Sbjct: 118 YVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHG 162 >2LAP-A nrPDB Length = 167 Score = 120 bits (301), Expect = 3e-28, Method: Composition-based stats. Identities = 36/151 (23%), Positives = 78/151 (51%), Gaps = 8/151 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 PE+IEE +EAF FD+ + I G+ +R +G PT+ E++ + + Sbjct: 19 LRPEEIEELREAFREFDKDK--DGYINCRDLGNCMRTMGYMPTEMELIELSQQINM--NL 74 Query: 106 TKMMDFETFLPMLQ--HISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA-TLGE 162 +DF+ F+ ++ +++ D ++ + R FD G+G + +ELR + LG Sbjct: 75 GGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGH 134 Query: 163 RLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 ++ ++E+++ + + +G +++E FV+ + Sbjct: 135 QVGHRDIEEIIRDVDLNGDGRVDFEEFVRMM 165 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 L ++ E+ E R FDK+ +G + +L + + T+G TE E+ +L Sbjct: 12 LSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQIN 71 Query: 178 -DSNGCINYEAFVKHI 192 + G ++++ FV+ + Sbjct: 72 MNLGGHVDFDDFVELM 87 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 32/71 (45%), Gaps = 5/71 (7%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRAL-GQNPTQAEVLRVLGKPRQEELNTKMM 109 ++E ++AF FD + +I+ + + +R L G ++ ++ + + Sbjct: 101 VKELRDAFREFDTN--GDGEISTSELREAMRKLLGHQVGHRDIEEII--RDVDLNGDGRV 156 Query: 110 DFETFLPMLQH 120 DFE F+ M+ Sbjct: 157 DFEEFVRMMSR 167 >3KF9-A nrPDB Length = 149 Score = 119 bits (299), Expect = 7e-28, Method: Composition-based stats. Identities = 41/148 (27%), Positives = 77/148 (52%), Gaps = 7/148 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQ +E +EAF LFD I + +RALG P + E+ +++ ++ Sbjct: 2 LTEEQKQEIREAFDLFDTD--GSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKD--G 57 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 + +DFE FL M+ +D + E+ ++ R+FD + G + L+ V LGE +T Sbjct: 58 SGTIDFEEFLQMMTAKMGERD--SREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMT 115 Query: 166 EDEVEKLMAGQE-DSNGCINYEAFVKHI 192 ++E+++++ + D +G +N E F + + Sbjct: 116 DEELQEMIDEADRDGDGEVNEEEFFRIM 143 Score = 57.0 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 ++ E +FD +G+GT+ EL+ + LG ++E++K++A + D +G I++ Sbjct: 4 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDF 63 Query: 186 EAFVKHIMS 194 E F++ + + Sbjct: 64 EEFLQMMTA 72 >3J04-B nrPDB Length = 143 Score = 119 bits (297), Expect = 1e-27, Method: Composition-based stats. Identities = 40/151 (26%), Positives = 68/151 (45%), Gaps = 11/151 (7%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F QI+EFKEAF + D+ + I D+L ++G+NPT + ++ + Sbjct: 1 FDQSQIQEFKEAFNMIDQNR--DGFIDKEDLHDMLASMGKNPTDEYLEGMMSEA------ 52 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL M D + FD+E +G + LR +L T+G+R T Sbjct: 53 PGPINFTMFLTMFGEKLNGTDP--EDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFT 110 Query: 166 EDEVEKLMAGQE-DSNGCINYEAFVKHIMSS 195 ++EV+++ D G NY F + + Sbjct: 111 DEEVDEMYREAPIDKKGNFNYVEFTRILKHG 141 >2BL0-C nrPDB Length = 142 Score = 117 bits (294), Expect = 2e-27, Method: Composition-based stats. Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 6/147 (4%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTK 107 +Q+ EFKEAF LFD + IT VL+ G A + + + Sbjct: 2 DDQVSEFKEAFELFD--SERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNE--ADATGNG 57 Query: 108 MMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTED 167 + F FL M+ K T + + + R FD EG G + A L+ L LG+RL Sbjct: 58 KIQFPEFLSMMGRRMK--QTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPH 115 Query: 168 EVEKLMAGQEDSNGCINYEAFVKHIMS 194 E + + E G I Y+ F+ + + Sbjct: 116 EFAEFLGITETEKGQIRYDNFINTMFT 142 >2OBH-A nrPDB Length = 143 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 41/147 (27%), Positives = 78/147 (53%), Gaps = 7/147 (4%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 T EQ +E +EAF LFD I + +RALG P + E+ +++ + +E T Sbjct: 1 TEEQKQEIREAFDLFDAD--GTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKE--GT 56 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 M+F FL ++ KD T E+ ++ ++FD + G + L+ V LGE LT+ Sbjct: 57 GKMNFGDFLTVMTQKMSEKD--TKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD 114 Query: 167 DEVEKLMAGQE-DSNGCINYEAFVKHI 192 +E+++++ + D +G ++ + F++ + Sbjct: 115 EELQEMIDEADRDGDGEVSEQEFLRIM 141 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 + + EE +AF LFD KI++ V + LG+N T E+ ++ + ++ Sbjct: 70 QKMSEKDTKEEILKAFKLFD--DDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD 127 Query: 103 ELNTKMMDFETFLPMLQH 120 + + FL +++ Sbjct: 128 --GDGEVSEQEFLRIMKK 143 >3DTP-E nrPDB Length = 196 Score = 114 bits (285), Expect = 3e-26, Method: Composition-based stats. Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 16/168 (9%) Query: 31 RPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQA 90 + + + S + FT Q++EFKEAF L D+ + I+ +LG+ T+ Sbjct: 36 QKRRAQRSGSNVFAMFTQHQVQEFKEAFQLIDQDK--DGFISKNDIRATFDSLGRLCTEQ 93 Query: 91 EVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYED--FVEGLRVFDKEGNGTV 148 E+ ++ + ++F FL + ++ GT E+ V +FD EG+G Sbjct: 94 ELDSMVAEA------PGPINFTMFLTIFG----DRIAGTDEEDVIVNAFNLFD-EGDGKC 142 Query: 149 MGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMSS 195 L+ L T GE+ ++DEV++ ++ D NG I+ + F + + Sbjct: 143 KEETLKRSLTTWGEKFSQDEVDQALSEAPIDGNGLIDIKKFAQILTKG 190 >2JNF-A nrPDB Length = 158 Score = 112 bits (279), Expect = 1e-25, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 78/155 (50%), Gaps = 6/155 (3%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 + + Q++ + AF F+ TP+ +++ Q G +L LG T++ + +++ + + Sbjct: 5 SKLSSNQVKLLETAFRDFE-TPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEF--DP 61 Query: 104 LNTKMMDFETFLPMLQHISKNKD--TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 +DF++F + + ++ E R++DKEGNG + +R +LA L Sbjct: 62 FGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAELD 121 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMSS 195 E L+ ++++ ++ + D +G +++E F+ + Sbjct: 122 ETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMTGG 156 >1I84-U nrPDB Length = 166 Score = 111 bits (277), Expect = 2e-25, Method: Composition-based stats. Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 10/158 (6%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 +S + F +IE+FKEAF + D+ + I + A+G+ + E L + K Sbjct: 12 SSNVFSMFDETEIEDFKEAFTVIDQN--ADGIIDKDDLRETFAAMGRLNVKNEELDAMIK 69 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 +N F FL M K D + + +V D +G G++ + L +L Sbjct: 70 EASGPIN-----FTVFLTMFGEKLKGADP--EDVIMGAFKVLDPDGKGSIKKSFLEELLT 122 Query: 159 TLGERLTEDEVEKLMAG-QEDSNGCINYEAFVKHIMSS 195 T G R T +E++ + A D G ++Y+ I Sbjct: 123 TGGGRFTPEEIKNMWAAFPPDVAGNVDYKNICYVITHG 160 >5H53-B nrPDB Length = 146 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 10/149 (6%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTK 107 QI+EFKEAF + D+ + I D A+G+ + E L + K +N Sbjct: 1 QTQIQEFKEAFTVIDQNR--DGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEASGPIN-- 56 Query: 108 MMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTED 167 F FL M K D + +V D EG GT+ L +L T +R +++ Sbjct: 57 ---FTVFLTMFGEKLKGADP--EDVITGAFKVLDPEGKGTIKKQFLEELLITQCDRFSQE 111 Query: 168 EVEKLMAGQ-EDSNGCINYEAFVKHIMSS 195 E++ + A D G ++Y+ I Sbjct: 112 EIKNMWAAFSPDVGGNVDYKNICYVITHG 140 >5W1A-B nrPDB Length = 155 Score = 106 bits (264), Expect = 8e-24, Method: Composition-based stats. Identities = 53/148 (35%), Positives = 80/148 (54%), Gaps = 9/148 (6%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTK 107 ++E + F + + I GD LRAL NPT A + ++ G ++ N K Sbjct: 6 KREVENVEFVFEVMGSPGEG---IDAVDLGDALRALNLNPTLALIEKLGGTKKR---NEK 59 Query: 108 MMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTED 167 + + FLP+ + K K+ G YEDF+E L+++DKE NGT++ AEL+H L LGE L ++ Sbjct: 60 KIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDE 119 Query: 168 EVEKLMA---GQEDSNGCINYEAFVKHI 192 +VE L A ED G I Y F+ + Sbjct: 120 QVETLFADCMDPEDDEGFIPYSPFLARM 147 Score = 28.1 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 32/79 (40%), Gaps = 2/79 (2%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP 99 S++K E E+F E L+D+ M + + L ALG++ +V + Sbjct: 71 SQVKKEKEQGCYEDFIECLKLYDKEENGTMLLA--ELQHALLALGESLDDEQVETLFADC 128 Query: 100 RQEELNTKMMDFETFLPML 118 E + + + FL + Sbjct: 129 MDPEDDEGFIPYSPFLARM 147 >1O1A-B nrPDB Length = 145 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 10/151 (6%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F +IE+FKEAF + D+ + I + A+G+ + E L + K +N Sbjct: 1 FDETEIEDFKEAFTVIDQN--ADGIIDKDDLRETFAAMGRLNVKNEELDAMIKEASGPIN 58 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 F FL M K D + + +V D +G G++ + L +L T G R T Sbjct: 59 -----FTVFLTMFGEKLKGADP--EDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFT 111 Query: 166 EDEVEKLMAG-QEDSNGCINYEAFVKHIMSS 195 +E++ + A D G ++Y+ I Sbjct: 112 PEEIKNMWAAFPPDVAGNVDYKNICYVITHG 142 >2M29-A nrPDB Length = 171 Score = 104 bits (258), Expect = 4e-23, Method: Composition-based stats. Identities = 39/145 (26%), Positives = 69/145 (47%), Gaps = 8/145 (5%) Query: 55 KEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETF 114 + AF FD + I Y + GD +R LG PT+ E+L V + +DFE F Sbjct: 31 QAAFEEFDTDQ--DGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKM--RMGGFVDFEEF 86 Query: 115 LPMLQHISKNKDTGT--YEDFVEGLRVFDKEGNGTVMGAELRHVL-ATLGERLTEDEVEK 171 + ++ + + + R FDK+ +G + AELR A LGE L E+++ Sbjct: 87 VELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDE 146 Query: 172 LMAGQE-DSNGCINYEAFVKHIMSS 195 ++ + + +G I+++ FV + + Sbjct: 147 MLREMDLNGDGTIDFDEFVMMLSTG 171 >5VT9-A nrPDB Length = 152 Score = 99.8 bits (247), Expect = 6e-22, Method: Composition-based stats. Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 11/157 (7%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDR--TPKCEMKITYGQCGDVLRALGQNPTQAEVLRVL 96 S E E +EE EA ++ R K++ G + R LG P+ A+ Sbjct: 1 GSMGADEDMQEALEEMVEADEMYARFNARASGGKVSTGDAMILARQLGLAPSYAD----- 55 Query: 97 GKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 156 K EE + +D+ +F + + +D ED VE FD +G + ++ ++ Sbjct: 56 -KQAFEEKSGDNLDYASFQKFVGTSTHPEDNI--EDLVEAFAYFDVSKHGYLTRKQMGNI 112 Query: 157 LATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 L T GE LT +E L A + ++ I+Y F K ++ Sbjct: 113 LMTYGEPLTTEEFNAL-AAEYFTSDQIDYRQFCKAML 148 >5B7X-A nrPDB Length = 156 Score = 95.5 bits (236), Expect = 1e-20, Method: Composition-based stats. Identities = 36/142 (25%), Positives = 70/142 (49%), Gaps = 7/142 (4%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 ++ ++ F +DR + KI Q G ++R+LG PT+ EV + + E + Sbjct: 13 QKIRDCFNFYDRD--YDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEG---ETFQI 67 Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 E F +++ DT + VFD++ +G + ++L H L T+G+++T++EVEK Sbjct: 68 EQFELIMEREQSKPDT-REIKLRKAFEVFDQDKDGKIKASDLAHNLTTVGDKMTKEEVEK 126 Query: 172 LMAGQ-EDSNGCINYEAFVKHI 192 + + I+ F+K + Sbjct: 127 VFSILGITMESDIDLATFLKLV 148 >2KN2-A nrPDB Length = 92 Score = 95.1 bits (235), Expect = 2e-20, Method: Composition-based stats. Identities = 32/70 (45%), Positives = 49/70 (70%), Gaps = 1/70 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCIN 184 DT E+ E +VFDK+ NG + +ELRHV+ LGE+LT++EVE+++ + D +G +N Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 63 Query: 185 YEAFVKHIMS 194 YE FVK +M+ Sbjct: 64 YEEFVKMMMT 73 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 37/92 (40%), Gaps = 4/92 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + EE KEAF +FD+ I+ + V+ LG+ T EV +++ + + Sbjct: 3 MDTDAEEELKEAFKVFDKDQN--GYISASELRHVMINLGEKLTDEEVEQMIKEADLD--G 58 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGL 137 +++E F+ M+ + + Sbjct: 59 DGQVNYEEFVKMMMTVRGGGGGNGWSRLRRKF 90 >4WPX-A nrPDB Length = 177 Score = 94.4 bits (233), Expect = 3e-20, Method: Composition-based stats. Identities = 33/167 (19%), Positives = 73/167 (43%), Gaps = 15/167 (8%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 + + + EQ EAF LFD + ++Y + VLRALG + + + +L + Sbjct: 13 PREDYNKLSDEQKTRISEAFELFDSNK--DGLLSYEEFRFVLRALGFDLPKQQTYDMLVR 70 Query: 99 PRQEELN----------TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTV 148 Q N + + T + + + +D ++ R+FD +G G + Sbjct: 71 HGQRPANWPHDQECPPVYRQFNLATAQALAGTLIRQRDP--RDELRRAFRLFDVDGKGMI 128 Query: 149 MGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 +LR V +G + + +++ ++ + + G ++ + F++ +MS Sbjct: 129 TEDDLRKVCQQVGNNIPDADIQAMIEEFDSNGKGGVDEDEFLRLMMS 175 >3I5H-B nrPDB Length = 153 Score = 92.1 bits (227), Expect = 1e-19, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 63/147 (42%), Gaps = 10/147 (6%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 +++ + Q++E KEAF + D+ + I D+ +LG+ P E+ +L + Sbjct: 7 RVKLSQRQMQELKEAFTMIDQDR--DGFIGMEDLKDMFSSLGRVPPDDELNAMLKEC--- 61 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 162 ++F FL + D + +FD++G G + L+ +L +G+ Sbjct: 62 ---PGQLNFTAFLTLFGEKVSGTDP--EDALRNAFSMFDEDGQGFIPEDYLKDLLENMGD 116 Query: 163 RLTEDEVEKLMAGQEDSNGCINYEAFV 189 +++E++ + N NY V Sbjct: 117 NFSKEEIKNVWKDAPLKNKQFNYNKMV 143 >3IFK-A nrPDB Length = 90 Score = 92.1 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 37/94 (39%), Positives = 53/94 (56%), Gaps = 6/94 (6%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 3 QLTEEQIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD-- 58 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLR 138 +DF FL M+ K DT + E+ E R Sbjct: 59 GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFR 90 Score = 65.5 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 +F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D NG I++ Sbjct: 6 EEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 65 Query: 186 EAFVKHI 192 F+ + Sbjct: 66 PEFLTMM 72 >1S6I-A nrPDB Length = 188 Score = 91.7 bits (226), Expect = 2e-19, Method: Composition-based stats. Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 10/148 (6%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + E+I KE F + D IT+ + D L+ +G ++E+ ++ ++ Sbjct: 4 LSEEEIGGLKELFKMIDTDNS--GTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSG 61 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 T +D+ F+ H++K E+ V FDK+G+G + E++ G L Sbjct: 62 T--IDYGEFIAATVHLNK---LEREENLVSAFSYFDKDGSGYITLDEIQQACKDFG--LD 114 Query: 166 EDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + ++ ++ + D++G I+Y F + Sbjct: 115 DIHIDDMIKEIDQDNDGQIDYGEFAAMM 142 >2I08-A nrPDB Length = 78 Score = 90.9 bits (224), Expect = 3e-19, Method: Composition-based stats. Identities = 31/79 (39%), Positives = 46/79 (58%), Gaps = 4/79 (5%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF L+D+ + IT + G V+R+LG NPT+AE+ ++ + + Sbjct: 3 QLTEEQIAEFKEAFSLYDKD--GDGTITTKELGTVMRSLGLNPTEAELQDMINEVDAD-- 58 Query: 105 NTKMMDFETFLPMLQHISK 123 +DF FL M+ I K Sbjct: 59 GNGTIDFPEFLTMMARIMK 77 Score = 67.4 bits (163), Expect = 4e-12, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 +F E ++DK+G+GT+ EL V+ +LG TE E++ ++ + D NG I++ Sbjct: 6 EEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDF 65 Query: 186 EAFVKHI 192 F+ + Sbjct: 66 PEFLTMM 72 >1FW4-A nrPDB Length = 71 Score = 90.5 bits (223), Expect = 4e-19, Method: Composition-based stats. Identities = 32/70 (45%), Positives = 50/70 (71%), Gaps = 1/70 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCIN 184 DT + E+ E RVFDK+GNG + AELRHV+ LGE+LT++EV++++ + D +G +N Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 60 Query: 185 YEAFVKHIMS 194 YE FV+ + + Sbjct: 61 YEEFVQMMTA 70 Score = 46.6 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 4/70 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE +EAF +FD+ I+ + V+ LG+ T EV ++ + + +++ Sbjct: 6 EEIREAFRVFDKD--GNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID--GDGQVNY 61 Query: 112 ETFLPMLQHI 121 E F+ M+ Sbjct: 62 EEFVQMMTAK 71 >2M5E-A nrPDB Length = 73 Score = 90.1 bits (222), Expect = 5e-19, Method: Composition-based stats. Identities = 32/72 (44%), Positives = 52/72 (72%), Gaps = 1/72 (1%) Query: 124 NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGC 182 K+ + E+ +E +VFD++GNG + AELRHV+ LGE+LT+DEV++++ + D +G Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGH 60 Query: 183 INYEAFVKHIMS 194 INYE FV+ ++S Sbjct: 61 INYEEFVRMMVS 72 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 4/71 (5%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTK 107 + EE EAF +FDR I+ + V+ LG+ T EV ++ + + Sbjct: 4 QDSEEELIEAFKVFDRD--GNGLISAAELRHVMTNLGEKLTDDEVDEMIREADID--GDG 59 Query: 108 MMDFETFLPML 118 +++E F+ M+ Sbjct: 60 HINYEEFVRMM 70 >2KZ2-A nrPDB Length = 94 Score = 89.4 bits (220), Expect = 1e-18, Method: Composition-based stats. Identities = 33/75 (44%), Positives = 51/75 (68%), Gaps = 1/75 (1%) Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DS 179 S KDT + E+ E RV DK+GNG + AELRHV+ LGE+LT++EV++++ + D Sbjct: 19 QSLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDG 78 Query: 180 NGCINYEAFVKHIMS 194 +G +NYE FV+ + + Sbjct: 79 DGQVNYEEFVQMMTA 93 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 + + EE +EAF + D+ I+ + V+ LG+ T EV ++ + + Sbjct: 21 LMKDTDSEEEIREAFRVEDKD--GNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID- 77 Query: 104 LNTKMMDFETFLPMLQHI 121 +++E F+ M+ Sbjct: 78 -GDGQVNYEEFVQMMTAK 94 >5H7D-E nrPDB Length = 120 Score = 88.6 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 10/94 (10%) Query: 27 PEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQN 86 +P + + +A K+ QI+ FKEAF LFD+ + IT + G V+R+LGQN Sbjct: 37 DDPSQSANLLAEAKKL------NQIQAFKEAFSLFDKD--GDGTITTKELGTVMRSLGQN 88 Query: 87 PTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQH 120 PT+AE+ ++ + + +DF FL M+ Sbjct: 89 PTEAELQDMINEVDAD--GNGTIDFPEFLTMMAR 120 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 1/73 (1%) Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DS 179 +++ K + F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D Sbjct: 46 LAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 105 Query: 180 NGCINYEAFVKHI 192 NG I++ F+ + Sbjct: 106 NGTIDFPEFLTMM 118 >5COC-A nrPDB Length = 130 Score = 88.6 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 30/76 (39%), Positives = 43/76 (56%), Gaps = 4/76 (5%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTK 107 E I EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 59 EECIAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD--GNG 114 Query: 108 MMDFETFLPMLQHISK 123 +DF FL M+ K Sbjct: 115 TIDFPEFLTMMARKMK 130 Score = 74.0 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSN 180 ++ +F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D N Sbjct: 54 AQAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 113 Query: 181 GCINYEAFVKHI 192 G I++ F+ + Sbjct: 114 GTIDFPEFLTMM 125 >2AAO-A nrPDB Length = 166 Score = 88.6 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 36/155 (23%), Positives = 71/155 (45%), Gaps = 10/155 (6%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 I + E+I KE F + D + IT+ + L+ +G N ++E+L ++ Sbjct: 17 IAESLSEEEIAGLKEMFNMIDADKSGQ--ITFEELKAGLKRVGANLKESEILDLMQAADV 74 Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 161 + N+ +D++ F+ H++K + FDK+G+G + EL+ G Sbjct: 75 D--NSGTIDYKEFIAATLHLNK---IEREDHLFAAFTYFDKDGSGYITPDELQQACEEFG 129 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMSS 195 + + +E+LM + D++G I+Y FV + Sbjct: 130 --VEDVRIEELMRDVDQDNDGRIDYNEFVAMMQKG 162 >2RO8-A nrPDB Length = 79 Score = 87.4 bits (215), Expect = 3e-18, Method: Composition-based stats. Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 4/80 (5%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQI EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + Sbjct: 3 QLTDEQISEFKEAFSLFDKD--GDGCITTKELGTVMRSLGQNPTEAELQDMINEVDAD-- 58 Query: 105 NTKMMDFETFLPMLQHISKN 124 +DF FL ++ K+ Sbjct: 59 GNGTIDFPEFLNLMARKMKD 78 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 +F E +FDK+G+G + EL V+ +LG+ TE E++ ++ + D NG I++ F+ Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLN 70 Query: 191 HI 192 + Sbjct: 71 LM 72 >2ROB-A nrPDB Length = 70 Score = 86.3 bits (212), Expect = 7e-18, Method: Composition-based stats. Identities = 30/68 (44%), Positives = 47/68 (69%), Gaps = 1/68 (1%) Query: 128 GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYE 186 E+ E +VFDK+ NG + +ELRHV+ LGE+LT++EVE+++ + D +G +NYE Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 187 AFVKHIMS 194 FVK +M+ Sbjct: 61 EFVKMMMT 68 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 + EE KEAF +FD+ I+ + V+ LG+ T EV +++ + + Sbjct: 1 DAEEELKEAFKVFDKDQN--GYISASELRHVMINLGEKLTDEEVEQMIKEADLD--GDGQ 56 Query: 109 MDFETFLPML 118 +++E F+ M+ Sbjct: 57 VNYEEFVKMM 66 >2RO9-A nrPDB Length = 69 Score = 85.9 bits (211), Expect = 9e-18, Method: Composition-based stats. Identities = 32/68 (47%), Positives = 48/68 (70%), Gaps = 1/68 (1%) Query: 128 GTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYE 186 + E+ E RVFDK+ NG + AELRHV+ LGE+LT++EV++++ + D +G INYE Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 187 AFVKHIMS 194 FVK +M+ Sbjct: 61 EFVKVMMA 68 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE KEAF +FD+ I+ + V+ LG+ T EV ++ + + +++ Sbjct: 4 EELKEAFRVFDKDQN--GFISAAELRHVMTNLGEKLTDEEVDEMIREADVD--GDGQINY 59 Query: 112 ETFLPML 118 E F+ ++ Sbjct: 60 EEFVKVM 66 >5ZOR-A nrPDB Length = 149 Score = 85.9 bits (211), Expect = 1e-17, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 67/149 (44%), Gaps = 9/149 (6%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI +EAF LFD I + ++ LG + + + Sbjct: 4 LTDEQI---REAFNLFDAD--GSGAIDAEEMALAMKGLGFGDLPRDEVERTVR-SMNTNA 57 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++++ F M+ S+ + E+ ++ ++FD + G + A L+ V LGE Sbjct: 58 NGLIEYGEFERMV--KSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPG 115 Query: 166 EDEVEKLMAG-QEDSNGCINYEAFVKHIM 193 +D +++++A ED +G +++E F +M Sbjct: 116 DDVLQEMIAEADEDGDGEVSFEEFKSVMM 144 >5MWC-D nrPDB Length = 311 Score = 83.6 bits (205), Expect = 4e-17, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Query: 97 GKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 156 G + E K F P++ S + E+ E R FDK+G+G + E + Sbjct: 118 GSHIKGEAQVKGTGFPADGPVMA-NSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGI 176 Query: 157 LATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + GE+LT+++ +++ + D NG I+++ F+K + Sbjct: 177 IRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKMV 213 Score = 54.3 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 15/107 (14%) Query: 13 AKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKIT 72 +A K PA P A+ + E+ E E F FD+ + I Sbjct: 123 GEAQVKGTGFPADGPVM---------ANSLTAMVPSEE--ELSECFRTFDKD--GDGFID 169 Query: 73 YGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQ 119 + G ++R G+ T + + G + +DF+ FL M++ Sbjct: 170 REEFGGIIRLTGEQLTDEDPDEIFG--DSDTDKNGRIDFDEFLKMVE 214 Score = 33.5 bits (75), Expect = 0.053, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 5/67 (7%) Query: 87 PTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNG 146 P++ E+ ++ +D E F +++ + T ED E D + NG Sbjct: 148 PSEEELSECFRTFDKD--GDGFIDREEFGGIIRLTG---EQLTDEDPDEIFGDSDTDKNG 202 Query: 147 TVMGAEL 153 + E Sbjct: 203 RIDFDEF 209 >2OS8-B nrPDB Length = 157 Score = 83.2 bits (204), Expect = 7e-17, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 10/154 (6%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 AS + + +QI+E KEAF + D+ + I ++ +LG+ P E+ +L + Sbjct: 6 ASGVLTKLPQKQIQEMKEAFTMIDQNR--DGFIDINDLKEMFSSLGRTPDDKELTAMLKE 63 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 ++F FL + K T + E +FD+ + ++ +L Sbjct: 64 A------PGPLNFTMFLSIFSD--KLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLE 115 Query: 159 TLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHI 192 +G+ +DE+ G +Y FV I Sbjct: 116 NMGDNFNKDEMRMTFKEAPVEGGKFDYVRFVAMI 149 >2N7L-C nrPDB Length = 141 Score = 82.0 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 26 QLTEEQKNEFKAAFDIFVL-GAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDED-- 82 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTY 130 + +DF+ FL M+ K+ Y Sbjct: 83 GSGTVDFDEFLVMMVRXMKDDSENLY 108 Score = 56.6 bits (135), Expect = 7e-09, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 39/82 (47%), Gaps = 6/82 (7%) Query: 118 LQHISKNKDTGTYEDFVEGLRV-FD----KEGNGTVMGAELRHVLATLGERLTEDEVEKL 172 + I K E+ + FD +G++ EL V+ LG+ T +E++++ Sbjct: 16 MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEM 75 Query: 173 MAG-QEDSNGCINYEAFVKHIM 193 + ED +G ++++ F+ ++ Sbjct: 76 IDEVDEDGSGTVDFDEFLVMMV 97 >5VLN-A nrPDB Length = 120 Score = 81.7 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 3/87 (3%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 11 QLTEEQKNEFKAAFDIFVL-GAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDED-- 67 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYE 131 + +DF+ FL M+ K+ G ++ Sbjct: 68 GSGTVDFDEFLVMMVRSMKDDSKGKFK 94 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 117 MLQHISKNKDTGTYEDFVEGLRVFD-KEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG 175 + + + +F +F +G++ EL V+ LG+ T +E+++++ Sbjct: 4 IYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDE 63 Query: 176 -QEDSNGCINYEAFVKHIMSS 195 ED +G ++++ F+ ++ S Sbjct: 64 VDEDGSGTVDFDEFLVMMVRS 84 >1F55-A nrPDB Length = 77 Score = 81.3 bits (199), Expect = 2e-16, Method: Composition-based stats. Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 4/78 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 T EQI EFKEAF LFD+ I+ + V+R+LG +P++AEV ++ + + Sbjct: 4 LTEEQIAEFKEAFALFDKDNN--GSISSSELATVMRSLGLSPSEAEVNDLMNEIDVD--G 59 Query: 106 TKMMDFETFLPMLQHISK 123 ++F FL ++ K Sbjct: 60 NHQIEFSEFLALMSRQLK 77 Score = 61.2 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 +F E +FDK+ NG++ +EL V+ +LG +E EV LM + D N I + Sbjct: 6 EEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEF 65 Query: 186 EAFVKHI 192 F+ + Sbjct: 66 SEFLALM 72 >3TS5-B nrPDB Length = 161 Score = 81.3 bits (199), Expect = 2e-16, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 59/153 (38%), Gaps = 10/153 (6%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP 99 S + + ++E KEAF + D+ + I ++ +LG+ P E+ +L + Sbjct: 11 SNVFARLPQKLMQEMKEAFTMIDQNR--DGFIDINDLKEMFSSLGRTPDDKELTAMLKEA 68 Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 ++F FL + K T + E +FD+ + ++ +L Sbjct: 69 ------PGPLNFTMFLSIFSD--KLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLEN 120 Query: 160 LGERLTEDEVEKLMAGQEDSNGCINYEAFVKHI 192 +G+ +DE+ G +Y FV I Sbjct: 121 MGDNFNKDEMRMTFKEAPVEGGKFDYVRFVAMI 153 >1B7T-Y nrPDB Length = 156 Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 60/154 (38%), Gaps = 10/154 (6%) Query: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 AS + + +QI+E KEAF + D + ++ + LG+ P E+ +L + Sbjct: 5 ASGVLTKLPQKQIQEMKEAFSMIDVDR--DGFVSKEDIKAISEQLGRAPDDKELTAMLKE 62 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 ++F FL + K T + E +FD++ + ++ +L Sbjct: 63 A------PGPLNFTMFLSIFSD--KLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLE 114 Query: 159 TLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHI 192 +G+ +DE+ G +Y F I Sbjct: 115 NMGDNFNKDEMRMTFKEAPVEGGKFDYVKFTAMI 148 >3LIJ-A nrPDB Length = 494 Score = 79.0 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 65/155 (41%), Gaps = 18/155 (11%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC--------GDVLRALGQNPTQAEVLRVLGK 98 + E+ +E + F D+ + ++ + G+ + ++EV +LG Sbjct: 341 SQEETKELTDIFRHIDKN--GDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGA 398 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 + +D+ F+ + K + + + FD++GNG + EL V Sbjct: 399 ADFDRNGY--IDYSEFVTV---AMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG 453 Query: 159 TLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + L +++++G + +++G +++E F K I Sbjct: 454 L--DHLESKTWKEMISGIDSNNDGDVDFEEFCKMI 486 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 9/81 (11%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GERLT-------EDEVEKLM 173 SK ++ + R DK G+G + EL + L GE + E EV+ ++ Sbjct: 337 SKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAIL 396 Query: 174 AGQE-DSNGCINYEAFVKHIM 193 + D NG I+Y FV M Sbjct: 397 GAADFDRNGYIDYSEFVTVAM 417 Score = 35.8 bits (81), Expect = 0.013, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 ++ + AF FD+ KI+ + V G + +++ + + + N +D Sbjct: 425 KDKLESAFQKFDQD--GNGKISVDELASVF---GLDHLESKTWKEMIS-GIDSNNDGDVD 478 Query: 111 FETFLPMLQHISKNKD 126 FE F M+Q + N + Sbjct: 479 FEEFCKMIQKLCSNNE 494 >4Q57-A nrPDB Length = 65 Score = 79.0 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 28/69 (40%), Positives = 41/69 (59%), Gaps = 4/69 (5%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 I EFKEAF LFD+ + IT + G V+R+LGQNPT+AE+ ++ + + +D Sbjct: 1 IAEFKEAFSLFDKD--GDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD--GNGTID 56 Query: 111 FETFLPMLQ 119 F FL M+ Sbjct: 57 FPEFLTMMA 65 Score = 70.5 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 +F E +FDK+G+GT+ EL V+ +LG+ TE E++ ++ + D NG I++ F+ Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 62 Query: 191 HI 192 + Sbjct: 63 MM 64 >1DFK-Y nrPDB Length = 139 Score = 77.8 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 56/147 (38%), Gaps = 10/147 (6%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 +QI+E KEAF + D + ++ + LG+ P E+ +L + Sbjct: 1 LPQKQIQEMKEAFSMIDVDR--DGFVSKEDIKAISEQLGRAPDDKELTAMLKEA------ 52 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++F FL + K T + E +FD++ + ++ +L +G+ Sbjct: 53 PGPLNFTMFLSIFSD--KLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFN 110 Query: 166 EDEVEKLMAGQEDSNGCINYEAFVKHI 192 +DE+ G +Y F I Sbjct: 111 KDEMRMTFKEAPVEGGKFDYVKFTAMI 137 >2EC6-B nrPDB Length = 133 Score = 77.4 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 56/142 (39%), Gaps = 10/142 (7%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 ++E KEAF + D+ + I + +LG+ P E+ +L + ++ Sbjct: 1 MQEMKEAFTMIDQNR--DGFIDINDLKEEFSSLGRTPDDKELTAMLKEA------PGPLN 52 Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVE 170 F FL + K T + E +FD++ + ++ +L +G+ +DE+ Sbjct: 53 FTMFLSIFSD--KLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMR 110 Query: 171 KLMAGQEDSNGCINYEAFVKHI 192 G +Y FV I Sbjct: 111 MTFKEAPVEGGKFDYVRFVAMI 132 >2HF5-A nrPDB Length = 68 Score = 77.4 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 28/72 (38%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 90 AEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVM 149 AE+ ++ + + +DF FL M+ K DT + E+ E RVFDK+GNG + Sbjct: 1 AELQDMINEVDAD--GNGTIDFPEFLTMMARKMK--DTDSEEEIREAFRVFDKDGNGYIS 56 Query: 150 GAELRHVLATLG 161 AELRHV+ LG Sbjct: 57 AAELRHVMTNLG 68 Score = 30.8 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 17/33 (51%), Gaps = 2/33 (6%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALG 84 EE +EAF +FD+ I+ + V+ LG Sbjct: 38 EEIREAFRVFDKD--GNGYISAAELRHVMTNLG 68 Score = 30.4 bits (67), Expect = 0.47, Method: Composition-based stats. Identities = 6/26 (23%), Positives = 15/26 (57%), Gaps = 1/26 (3%) Query: 168 EVEKLMAGQE-DSNGCINYEAFVKHI 192 E++ ++ + D NG I++ F+ + Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMM 27 >2AMI-A nrPDB Length = 96 Score = 77.4 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 4/85 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D K ++ T EQ +E +EAF LFD I + +RALG P + E+ +++ Sbjct: 16 DQKKGRVGLTEEQKQEIREAFDLFDTD--GSGTIDAKELKVAMRALGFEPKKEEIKKMIS 73 Query: 98 KPRQEELNTKMMDFETFLPMLQHIS 122 + ++ + +DFE FL M+ Sbjct: 74 EIDKD--GSGTIDFEEFLTMMTAKM 96 Score = 61.6 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 ++ E +FD +G+GT+ EL+ + LG ++E++K+++ + D +G I++ Sbjct: 26 EEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDF 85 Query: 186 EAFVKHIMS 194 E F+ + + Sbjct: 86 EEFLTMMTA 94 >4GJF-A nrPDB Length = 89 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Query: 45 EFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL 104 + T EQ EFK AF +F + + I+ + G V+R LGQNPT E+ ++ + ++ Sbjct: 11 QLTEEQKNEFKAAFDIFVQ-GAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDED-- 67 Query: 105 NTKMMDFETFLPMLQHISKNKD 126 + +DF+ FL M+ K+ Sbjct: 68 GSGTVDFDEFLVMMVRCMKDDS 89 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Query: 117 MLQHISKNKDTGTYEDFVEGLRVFDK-EGNGTVMGAELRHVLATLGERLTEDEVEKLMAG 175 + + + +F +F + +G + EL V+ LG+ T +E+++++ Sbjct: 4 IYKAAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDE 63 Query: 176 -QEDSNGCINYEAFVKHIM 193 ED +G ++++ F+ ++ Sbjct: 64 VDEDGSGTVDFDEFLVMMV 82 >1TRF-A nrPDB Length = 76 Score = 74.0 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 4/78 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + E I EFK AF +FD + I+ + G V+R LGQNPT+ E+ ++ + ++ Sbjct: 3 LSEEMIAEFKAAFDMFDADGGGD--ISTKELGTVMRMLGQNPTKEELDAIIEEVDED--G 58 Query: 106 TKMMDFETFLPMLQHISK 123 + +DFE FL M+ K Sbjct: 59 SGTIDFEEFLVMMVRQMK 76 Score = 59.7 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNGCIN 184 +F +FD +G G + EL V+ LG+ T++E++ ++ ED +G I+ Sbjct: 4 SEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTID 63 Query: 185 YEAFVKHIM 193 +E F+ ++ Sbjct: 64 FEEFLVMMV 72 >1TNP-A nrPDB Length = 90 Score = 74.0 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 4/88 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 ++ + + E I EFK AF +FD + I+ + G V+R LGQNPT+ E+ ++ Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGD--ISTKELGTVMRMLGQNPTKEELDAIIE 63 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNK 125 + ++ + +DFE FL M+ K Sbjct: 64 EVDED--GSGTIDFEEFLVMMVRQMKED 89 Score = 58.5 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNGCIN 184 +F +FD +G G + EL V+ LG+ T++E++ ++ ED +G I+ Sbjct: 15 SEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTID 74 Query: 185 YEAFVKHIM 193 +E F+ ++ Sbjct: 75 FEEFLVMMV 83 >2M8U-A nrPDB Length = 77 Score = 73.6 bits (179), Expect = 5e-14, Method: Composition-based stats. Identities = 25/73 (34%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN- 180 S T +E +VFD++GNG V LR VL LG+ + DE+E+++ + N Sbjct: 2 SHMNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNS 61 Query: 181 GCINYEAFVKHIM 193 G + YE FV + Sbjct: 62 GYVQYETFVGMLF 74 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 + EAF +FDR + + Y VL LG E+ ++ + + N+ + Sbjct: 10 KAQVIEAFKVFDRDGNGYVTVDY--LRKVLNELGDMMPADEIEEMIYE--ADPQNSGYVQ 65 Query: 111 FETFLPML 118 +ETF+ ML Sbjct: 66 YETFVGML 73 >3HZT-A nrPDB Length = 467 Score = 73.6 bits (179), Expect = 5e-14, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 64/158 (40%), Gaps = 21/158 (13%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC-----------GDVLRALGQNPTQAEVLRV 95 T E+ +E + F D + ++ + GD + L + +AEV + Sbjct: 309 TLEETKELTQIFRQLD--NNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHI 366 Query: 96 LGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRH 155 L + +++ F+ + + + E + + FD +G+G + EL Sbjct: 367 LQSVDFDRNGY--IEYSEFVTV---CMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGR 421 Query: 156 VLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + + ++ +++ + +++G +++E FV+ + Sbjct: 422 LFGVT--EVDDETWHQVLQECDKNNDGEVDFEEFVEMM 457 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL----RHVLATLGERLTE-------DEVE 170 SK ++ + R D G+G + EL R ++ G+ +++ EV+ Sbjct: 305 SKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 364 Query: 171 KLMAGQE-DSNGCINYEAFVKHIM 193 ++ + D NG I Y FV M Sbjct: 365 HILQSVDFDRNGYIEYSEFVTVCM 388 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 8/66 (12%) Query: 57 AFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEV-LRVLGKPRQEELNTKMMDFETFL 115 AF FD KIT + G R G E +VL + + N +DFE F+ Sbjct: 402 AFQQFD--SDGSGKITNEELG---RLFGVTEVDDETWHQVLQECDK--NNDGEVDFEEFV 454 Query: 116 PMLQHI 121 M+Q I Sbjct: 455 EMMQKI 460 >3O4Y-A nrPDB Length = 196 Score = 73.2 bits (178), Expect = 6e-14, Method: Composition-based stats. Identities = 32/149 (21%), Positives = 67/149 (44%), Gaps = 17/149 (11%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQN-PTQAEVLRVLGKPRQEELNTKMM 109 +++ K AF+ D + + IT Q L G P ++ +L + + + + Sbjct: 54 VQKLKAAFLHLDE--EGKGNITKLQLRKGLERSGLMLPPNFDL--LLDQIDSD--GSGNI 107 Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER--LTED 167 D+ FL + ++ + + RVFD + +G + AEL HVL +R +TE Sbjct: 108 DYTEFLA----AAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKRGNITER 163 Query: 168 EVEK---LMAGQE-DSNGCINYEAFVKHI 192 +V + ++ + + +G I++ F + + Sbjct: 164 DVNQVKKMIREVDKNGDGKIDFYEFSEMM 192 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 2/73 (2%) Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 + I++ + + D+EG G + +LR L G L + + L+ + Sbjct: 42 MTIIAQQSNDYDVQKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPN-FDLLLDQID 100 Query: 178 -DSNGCINYEAFV 189 D +G I+Y F+ Sbjct: 101 SDGSGNIDYTEFL 113 >2KSZ-A nrPDB Length = 76 Score = 73.2 bits (178), Expect = 7e-14, Method: Composition-based stats. Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 4/76 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + EQI +FKEAF LFD+ + IT + V+R+L QNPT+ E+ ++ + + Sbjct: 4 LSEEQIVDFKEAFGLFDKD--GDGCITVEELATVIRSLDQNPTEEELQDMISEVDAD--G 59 Query: 106 TKMMDFETFLPMLQHI 121 ++F+ FL ++ Sbjct: 60 NGTIEFDEFLSLMAKK 75 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 DF E +FDK+G+G + EL V+ +L + TE+E++ +++ + D NG I ++ F+ Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLS 70 Query: 191 HI 192 + Sbjct: 71 LM 72 >1M39-A nrPDB Length = 89 Score = 72.8 bits (177), Expect = 8e-14, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 48/85 (56%), Gaps = 3/85 (3%) Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 M+F FL ++ KD T E+ ++ ++FD + G + L+ V LGE LT++E Sbjct: 1 MNFGDFLTVMTQKMSEKD--TKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEE 58 Query: 169 VEKLMAGQE-DSNGCINYEAFVKHI 192 +++++ + D +G ++ + F++ + Sbjct: 59 LQEMIDEADRDGDGEVSEQEFLRIM 83 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 + + EE +AF LFD KI++ V + LG+N T E+ ++ + ++ Sbjct: 12 QKMSEKDTKEEILKAFKLFD--DDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD 69 Query: 103 ELNTKMMDFETFLPMLQHIS 122 + + FL +++ S Sbjct: 70 --GDGEVSEQEFLRIMKKTS 87 >3L19-A nrPDB Length = 214 Score = 72.8 bits (177), Expect = 9e-14, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 65/155 (41%), Gaps = 18/155 (11%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC--------GDVLRALGQNPTQAEVLRVLGK 98 + E+ +E + F D+ + ++ + G+ + ++EV +LG Sbjct: 58 SQEETKELTDIFRHIDKN--GDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGA 115 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 + +D+ F+ + K + + + FD++GNG + EL V Sbjct: 116 ADFDRNGY--IDYSEFVTV---AMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG 170 Query: 159 TLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + L +++++G + +++G +++E F K I Sbjct: 171 L--DHLESKTWKEMISGIDSNNDGDVDFEEFCKMI 203 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 9/81 (11%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GERLT-------EDEVEKLM 173 SK ++ + R DK G+G + EL + L GE + E EV+ ++ Sbjct: 54 SKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAIL 113 Query: 174 AGQE-DSNGCINYEAFVKHIM 193 + D NG I+Y FV M Sbjct: 114 GAADFDRNGYIDYSEFVTVAM 134 Score = 33.5 bits (75), Expect = 0.052, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 33/77 (42%), Gaps = 6/77 (7%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 ++ + AF FD+ KI+ + V G + +++ + + + N +D Sbjct: 142 KDKLESAFQKFDQD--GNGKISVDELASVF---GLDHLESKTWKEMIS-GIDSNNDGDVD 195 Query: 111 FETFLPMLQHISKNKDT 127 FE F M+Q + N + Sbjct: 196 FEEFCKMIQKLCSNNEP 212 >2B1U-A nrPDB Length = 71 Score = 72.4 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 ED R FD++G+G + ELR +A LG+ L ++E++ ++ + D +G +NYE F Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFA 65 Query: 190 KHI 192 + + Sbjct: 66 RML 68 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 +E+ + AF FD+ + IT + + LGQ Q E+ ++ + ++ ++ Sbjct: 5 LEDLQVAFRAFDQD--GDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDG--RVN 60 Query: 111 FETFLPMLQH 120 +E F ML Sbjct: 61 YEEFARMLAQ 70 >2FCE-A nrPDB Length = 70 Score = 72.0 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 31/68 (45%), Positives = 47/68 (69%), Gaps = 1/68 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 EDFV+ +VFDKE G V +LR++L LGE+LT+ EV++L+ G E DSNG I+Y Sbjct: 1 KAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDY 60 Query: 186 EAFVKHIM 193 + F++ ++ Sbjct: 61 KKFIEDVL 68 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 E+F +AF +FD+ + K++ G +L LG+ T AEV +L + + +D+ Sbjct: 5 EDFVKAFQVFDK--ESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVD--SNGEIDY 60 Query: 112 ETFLPMLQHI 121 + F+ + Sbjct: 61 KKFIEDVLRQ 70 >3Q5I-A nrPDB Length = 504 Score = 72.0 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 26/156 (16%), Positives = 65/156 (41%), Gaps = 20/156 (12%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC---GDVLR----ALG-QNPTQAEVLRVLGK 98 T E+ +E + F D+ + ++ + +VLR LG + EV +L + Sbjct: 350 TLEERKELTDIFKKLDKN--GDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKE 407 Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV-- 156 ++ +++ F+ + + + E +FD + +G + EL ++ Sbjct: 408 VDFDKNGY--IEYSEFISV---CMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLFG 462 Query: 157 LATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHI 192 L ++ E+ D + + ++ + I+++ FV + Sbjct: 463 LTSISEKTWNDVLGE---ADQNKDNMIDFDEFVSMM 495 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 9/81 (11%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAE-------LRHVLATLGE-RLTEDEVEKLM 173 SK ++ + + DK G+G + E LR+ LGE + E+EV+ ++ Sbjct: 346 SKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNIL 405 Query: 174 AGQE-DSNGCINYEAFVKHIM 193 + D NG I Y F+ M Sbjct: 406 KEVDFDKNGYIEYSEFISVCM 426 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 20/101 (19%) Query: 33 KEVEFDASKIKIEFTP-------EQI----EEFKEAFMLFDRTPKCEMKITYGQCGDVLR 81 KEV+FD IE++ +QI E + AF LFD KIT + ++ Sbjct: 406 KEVDFD-KNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKS--GKITKEELANLF- 461 Query: 82 ALGQNP-TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHI 121 G ++ VLG+ Q + N M+DF+ F+ M+ I Sbjct: 462 --GLTSISEKTWNDVLGEADQNKDN--MIDFDEFVSMMHKI 498 >4JWQ-A nrPDB Length = 199 Score = 71.3 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 63/148 (42%), Gaps = 15/148 (10%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 +++ K F+ D K IT Q L G +L + + + +D Sbjct: 57 LQQLKTVFLYLDEDGKGN--ITKNQLKKGLENSGLKL-PQNFDVLLDQIDSD--GSGRID 111 Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER--LTEDE 168 + FL + ++ + + RVFD + +G + AEL H+L ++ +T+ + Sbjct: 112 YTEFLA----AALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKD 167 Query: 169 VEK---LMAGQE-DSNGCINYEAFVKHI 192 V + ++ + +++G I++ F + + Sbjct: 168 VNQVKKMIQEVDKNNDGKIDFYEFCEMM 195 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 33/73 (45%), Gaps = 2/73 (2%) Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 + I++ + + D++G G + +L+ L G +L ++ + L+ + Sbjct: 45 MTIIAQQSNDYDLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQN-FDVLLDQID 103 Query: 178 -DSNGCINYEAFV 189 D +G I+Y F+ Sbjct: 104 SDGSGRIDYTEFL 116 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 29/71 (40%), Gaps = 11/71 (15%) Query: 57 AFMLFDRTPKCEMKITYGQCGDVLR------ALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 AF +FD + +IT + +L ++ Q V +++ + + N +D Sbjct: 133 AFRVFDVDN--DGEITTAELAHILYNGNKKGSITQKDVNQ-VKKMIQEVDK--NNDGKID 187 Query: 111 FETFLPMLQHI 121 F F M++ Sbjct: 188 FYEFCEMMKLK 198 >4OCI-A nrPDB Length = 146 Score = 70.5 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 56/140 (40%), Gaps = 9/140 (6%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 E+ KE+F+LFD + +T + ++R LG E + M + Sbjct: 6 EDLKESFLLFD--GDGDGYLTLNEFESLVRVLGVV---METSAIASTYNSNSKVRG-MSY 59 Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 E F + ++ + V DK+ G + ELR +L+T+G+ + + E+ Sbjct: 60 ELFTSCFSQLKTKSF--NKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEITD 117 Query: 172 LMAGQ-EDSNGCINYEAFVK 190 L D G + + F+ Sbjct: 118 LFTFMGIDEQGVVKVDDFIN 137 >1ZMZ-A nrPDB Length = 98 Score = 70.1 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 4/80 (5%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 K E T EQ +E +EAF LFD I + +RALG P + E+ +++ + +E Sbjct: 22 KPELTEEQKQEIREAFDLFDAD--GTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKE 79 Query: 103 ELNTKMMDFETFLPMLQHIS 122 T M+F FL ++ Sbjct: 80 --GTGKMNFGDFLTVMTQKM 97 Score = 50.1 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINY 185 ++ E +FD +G GT+ EL+ + LG ++E++K+++ + + G +N+ Sbjct: 27 EEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNF 86 Query: 186 EAFVKHIM 193 F+ + Sbjct: 87 GDFLTVMT 94 >3TZ1-A nrPDB Length = 74 Score = 69.7 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 27/68 (39%), Positives = 40/68 (58%), Gaps = 1/68 (1%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEA 187 + E RV DKE G + LR +L +LG+ LTEDE+E ++A + D +G ++YE Sbjct: 5 DERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEE 64 Query: 188 FVKHIMSS 195 F +MSS Sbjct: 65 FKCLMMSS 72 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 34/66 (51%), Gaps = 4/66 (6%) Query: 53 EFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFE 112 E KEAF + D+ K +K+ +L++LG T+ E+ ++ + + + +D+E Sbjct: 8 ELKEAFRVLDKEKKGVIKVDV--LRWILKSLGDELTEDEIENMIAETDTD--GSGTVDYE 63 Query: 113 TFLPML 118 F ++ Sbjct: 64 EFKCLM 69 >4AOM-A nrPDB Length = 146 Score = 69.3 bits (168), Expect = 9e-13, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 64/150 (42%), Gaps = 11/150 (7%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 I+ E+++E ++ KI+ R LG P+ + + + +E Sbjct: 7 IQQLEEKVDE--SDVRIYFNEKSSGGKISIDNASYNARKLGLAPSS------IDEKKIKE 58 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 L + +E +L L +KD E+ ++ FD G + ++++++L T G+ Sbjct: 59 LYGDNLTYEQYLEYLSICVHDKD--NVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDA 116 Query: 164 LTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 LT+ E + + I+Y+ F + I+ Sbjct: 117 LTDQEAIDALNAFSSED-NIDYKLFCEDIL 145 >3K21-A nrPDB Length = 191 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 64/148 (43%), Gaps = 15/148 (10%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 +E+ K F++ D K IT Q L G +L + + + +D Sbjct: 51 VEKLKSTFLVLDEDGK--GYITKEQLKKGLEKDGLKLPYN-FDLLLDQIDSD--GSGKID 105 Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER--LTEDE 168 + F+ + ++ + + RVFD + +G + AEL H+L ++ +T+ + Sbjct: 106 YTEFIA----AALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGNITQRD 161 Query: 169 VE---KLMAGQE-DSNGCINYEAFVKHI 192 V +++ + +++G I++ F + + Sbjct: 162 VNRVKRMIRDVDKNNDGKIDFHEFSEMM 189 Score = 43.5 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 32/73 (43%), Gaps = 2/73 (2%) Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 + I++ + E V D++G G + +L+ L G +L + L+ + Sbjct: 39 MTIIAQQSNDYDVEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKL-PYNFDLLLDQID 97 Query: 178 -DSNGCINYEAFV 189 D +G I+Y F+ Sbjct: 98 SDGSGKIDYTEFI 110 >4RGJ-A nrPDB Length = 520 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 66/157 (42%), Gaps = 17/157 (10%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMK-----ITYGQC----GDVLRALGQNPTQAEVLRVLG 97 T ++ +E + F D+ ++ I Y + G+ L + EV ++L Sbjct: 366 TIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILN 425 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 ++ +++ FL + K + E + ++FDK+G+G + EL + Sbjct: 426 SIDLDQNGY--IEYSEFLTV---SIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLF 480 Query: 158 ATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIM 193 ++ + + ++ + +++G I+++ F ++ Sbjct: 481 GLSD--VSSECWKTVLKEVDQNNDGEIDFKEFRDMLV 515 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 12/80 (15%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL----RHVLATLGERLTE-------DEVE 170 SK ++ + + DK G+G + EL + +L GE ++ EV+ Sbjct: 362 SKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVD 421 Query: 171 KLMAGQE-DSNGCINYEAFV 189 +++ + D NG I Y F+ Sbjct: 422 QILNSIDLDQNGYIEYSEFL 441 >2M97-A nrPDB Length = 69 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 41/65 (63%), Gaps = 1/65 (1%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEA 187 + E+ E R+FDK+GNG + E ++ GE+LT+++V+++ + D NG I+++ Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 188 FVKHI 192 F+K + Sbjct: 61 FLKMM 65 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE E F +FD+ I + GD++R G+ T +V + G + +DF Sbjct: 3 EELSECFRIFDKD--GNGFIDREEFGDIIRLTGEQLTDEDVDEIFG--DSDTDKNGRIDF 58 Query: 112 ETFLPMLQ 119 + FL M++ Sbjct: 59 DEFLKMME 66 >5JN2-A nrPDB Length = 525 Score = 68.9 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 21/159 (13%), Positives = 67/159 (42%), Gaps = 21/159 (13%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC----GDVLRALGQNPT-------QAEVLRV 95 + ++ +E F D+ + ++ + +++R GQ+ + + EV +V Sbjct: 371 SQDETKELTAIFHKMDKN--GDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQV 428 Query: 96 LGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRH 155 L ++ +++ F+ + K + E R+FD + +G + EL Sbjct: 429 LDAVDFDKNGY--IEYSEFVTV---AMDRKTLLSRERLERAFRMFDSDNSGKISSTELAT 483 Query: 156 VLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIM 193 + + + + +++ + +++G ++++ F + ++ Sbjct: 484 IFGVSD--VDSETWKSVLSEVDKNNDGEVDFDEFQQMLL 520 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL----RHVLATLGERLT-------EDEVE 170 SK ++ DK G+G + AEL + ++ G+ + E EV+ Sbjct: 367 SKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVD 426 Query: 171 KLMAGQE-DSNGCINYEAFVKHIM 193 +++ + D NG I Y FV M Sbjct: 427 QVLDAVDFDKNGYIEYSEFVTVAM 450 >4MVF-A nrPDB Length = 506 Score = 68.6 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 57/146 (39%), Gaps = 10/146 (6%) Query: 50 QIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109 +I + F+ D ++ + D L+ +G ++ +VL + + + Sbjct: 358 EINNLRNIFIALDVDNS--GTLSSQEILDGLKKIGYQKIPPDIHQVL--RDIDSNASGQI 413 Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL--ATLGERLTED 167 + FL I K + + FD +GNG + EL+ + + L + Sbjct: 414 HYTDFLA--ATIDKQTYLKKEVCLIP-FKFFDIDGNGKISVEELKRIFGRDDIENPLIDK 470 Query: 168 EVEKLMAGQE-DSNGCINYEAFVKHI 192 ++ L+ + + +G I++ F+ + Sbjct: 471 AIDSLLQEVDLNGDGEIDFHEFMLMM 496 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 23/68 (33%), Gaps = 8/68 (11%) Query: 58 FMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK---PRQEELNTKMMDFETF 114 F FD KI+ + R G++ + ++ + +DF F Sbjct: 438 FKFFDID--GNGKISVEELK---RIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEF 492 Query: 115 LPMLQHIS 122 + M+ + Sbjct: 493 MLMMSKLE 500 >5Z1Q-A nrPDB Length = 95 Score = 68.6 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 4/85 (4%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP 99 +++ E + EQ +E KEAF LFD I Y + +RALG + + E+L ++ + Sbjct: 15 KRVRQELSEEQKQEIKEAFDLFDTNKT--GSIDYHELKVAMRALGFDVKKPEILELMNEY 72 Query: 100 RQEELNTKMMDFETFLPMLQHISKN 124 +E + F+ FL ++ KN Sbjct: 73 DRE--GNGYIGFDDFLDIMTEKIKN 95 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 39/88 (44%), Gaps = 1/88 (1%) Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 K +F P + + + ++ E +FD G++ EL+ + LG + + Sbjct: 3 KKPEFGLMQPPKKRVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKK 62 Query: 167 DEVEKLMAGQE-DSNGCINYEAFVKHIM 193 E+ +LM + + NG I ++ F+ + Sbjct: 63 PEILELMNEYDREGNGYIGFDDFLDIMT 90 >2JOJ-A nrPDB Length = 77 Score = 67.8 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 + EQ +E KEAF LFD I Y + +RALG + + E+L ++ + +E Sbjct: 1 LSEEQKQEIKEAFDLFDTNKT--GSIDYHELKVAMRALGFDVKKPEILELMNEYDRE--G 56 Query: 106 TKMMDFETFLPMLQHISKNKD 126 + F+ FL ++ KN+D Sbjct: 57 NGYIGFDDFLDIMTEKIKNRD 77 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 32/69 (46%), Gaps = 1/69 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCIN 184 ++ E +FD G++ EL+ + LG + + E+ +LM + + NG I Sbjct: 2 SEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIG 61 Query: 185 YEAFVKHIM 193 ++ F+ + Sbjct: 62 FDDFLDIMT 70 >3KHE-A nrPDB Length = 191 Score = 67.0 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 64/158 (40%), Gaps = 21/158 (13%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC-----------GDVLRALGQNPTQAEVLRV 95 T E+ +E + F D + ++ + GD + L + +AEV + Sbjct: 35 TLEETKELTQIFRQLD--NNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHI 92 Query: 96 LGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRH 155 L + +++ F+ + + + E + + FD +G+G + EL Sbjct: 93 LQSVDFDRNGY--IEYSEFVTV---CMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGR 147 Query: 156 VLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + + ++ +++ + +++G +++E FV+ + Sbjct: 148 LFGVT--EVDDETWHQVLQECDKNNDGEVDFEEFVEMM 183 Score = 39.7 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL----RHVLATLGERLTE-------DEVE 170 SK ++ + R D G+G + EL R ++ G+ +++ EV+ Sbjct: 31 SKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVD 90 Query: 171 KLMAGQE-DSNGCINYEAFVKHIM 193 ++ + D NG I Y FV M Sbjct: 91 HILQSVDFDRNGYIEYSEFVTVCM 114 Score = 35.8 bits (81), Expect = 0.014, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 6/65 (9%) Query: 57 AFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLP 116 AF FD KIT + G R G E + + ++ N +DFE F+ Sbjct: 128 AFQQFD--SDGSGKITNEELG---RLFGVTEVDDETWHQVLQE-CDKNNDGEVDFEEFVE 181 Query: 117 MLQHI 121 M+Q I Sbjct: 182 MMQKI 186 >3NCG-A nrPDB Length = 486 Score = 66.6 bits (161), Expect = 7e-12, Method: Composition-based stats. Identities = 20/159 (12%), Positives = 60/159 (37%), Gaps = 18/159 (11%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC----GDVLRALG------QNPTQAEVLRVL 96 T ++ ++ E F D + + + + +R G + + + Sbjct: 326 TLDETKQLTEIFRKLDTNN--DGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQI 383 Query: 97 GKPRQ--EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELR 154 + + +++ F + + E ++FDK+G+G + EL Sbjct: 384 DSLMPLLDMDGSGSIEYSEF---IASAIDRTILLSRERMERAFKMFDKDGSGKISTKELF 440 Query: 155 HVLATLGERLTEDEVEKLMAGQEDS-NGCINYEAFVKHI 192 + + + +E+E ++ +++ +G +++ FV+ + Sbjct: 441 KLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEML 479 Score = 32.4 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 30/84 (35%), Gaps = 17/84 (20%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRH---------------VLATLGERLTE 166 SK + E R D +G + EL ++ G + E Sbjct: 322 SKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTI-E 380 Query: 167 DEVEKLMAGQE-DSNGCINYEAFV 189 D+++ LM + D +G I Y F+ Sbjct: 381 DQIDSLMPLLDMDGSGSIEYSEFI 404 >2K2A-A nrPDB Length = 70 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEA 187 ++ E R++DKEGNG + +R +LA L E L+ ++++ ++ + D +G +++E Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEE 60 Query: 188 FVKHIMSS 195 F+ + Sbjct: 61 FMGVMTGG 68 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Query: 50 QIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109 +E +EAF L+D+ + I+ ++L L + + ++ ++ + + + + Sbjct: 1 MQQELREAFRLYDK--EGNGYISTDVMREILAELDETLSSEDLDAMIDEIDAD--GSGTV 56 Query: 110 DFETFLPMLQ 119 DFE F+ ++ Sbjct: 57 DFEEFMGVMT 66 >2K7C-A nrPDB Length = 72 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 38/69 (55%), Gaps = 2/69 (2%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA-TLGERLTEDEVEKLMAGQE-DSNGCI 183 D ++ + R FD G+G + +ELR + LG ++ ++E+++ + + +G + Sbjct: 2 DMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRV 61 Query: 184 NYEAFVKHI 192 ++E FV+ + Sbjct: 62 DFEEFVRMM 70 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 32/71 (45%), Gaps = 5/71 (7%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRA-LGQNPTQAEVLRVLGKPRQEELNTKMM 109 ++E ++AF FD + +I+ + + +R LG ++ ++ + + Sbjct: 6 VKELRDAFREFDTN--GDGEISTSELREAMRKLLGHQVGHRDIEEII--RDVDLNGDGRV 61 Query: 110 DFETFLPMLQH 120 DFE F+ M+ Sbjct: 62 DFEEFVRMMSR 72 >1OQP-A nrPDB Length = 77 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 43/68 (63%), Gaps = 1/68 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCIN 184 + + E+ ++ R+FD + +GT+ +LR V LGE LTE+E+++++A + + + I+ Sbjct: 4 ERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEID 63 Query: 185 YEAFVKHI 192 + F++ + Sbjct: 64 EDEFIRIM 71 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 + EE +AF LFD IT V + LG+N T+ E+ ++ + + + N Sbjct: 6 DSREEILKAFRLFD--DDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDN--E 61 Query: 109 MDFETFLPMLQHIS 122 +D + F+ +++ S Sbjct: 62 IDEDEFIRIMKKTS 75 >2AUC-A nrPDB Length = 126 Score = 65.5 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 55/135 (40%), Gaps = 10/135 (7%) Query: 59 MLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPML 118 +F+ T K+ R LG P+ + ++ + +E +L L Sbjct: 2 DMFN-TKSSNGKLRIEDASHNARKLGLAPSSTDEKKIRDLY------GDSLTYEQYLEYL 54 Query: 119 QHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQED 178 ++D E+ ++ FD +G + +++++L T G+ LTE E + Sbjct: 55 TMCVHDRD--NMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSS 112 Query: 179 SNGCINYEAFVKHIM 193 + INY+ F + I+ Sbjct: 113 ED-RINYKLFCEDIL 126 >2LV7-A nrPDB Length = 100 Score = 65.5 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 4/76 (5%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 ++ +++EE +EAF +FDR I+ + G +R+LG P + E+ ++ + + Sbjct: 28 VDIPEDELEEIREAFKVFDRD--GNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMD- 84 Query: 104 LNTKMMDFETFLPMLQ 119 +DFE F+ +L Sbjct: 85 -GDGQVDFEEFVTLLG 99 Score = 64.7 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E+ E +VFD++GNG + EL + +LG E E+E ++ + D +G +++E FV Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFV 95 Query: 190 KHI 192 + Sbjct: 96 TLL 98 >3PM8-A nrPDB Length = 197 Score = 65.5 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 57/146 (39%), Gaps = 10/146 (6%) Query: 50 QIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMM 109 +I + F+ D ++ + D L+ +G ++ +VL + + + Sbjct: 55 EINNLRNIFIALDVDNS--GTLSSQEILDGLKKIGYQKIPPDIHQVL--RDIDSNASGQI 110 Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL--ATLGERLTED 167 + FL I K + + FD +GNG + EL+ + + L + Sbjct: 111 HYTDFLA--ATIDKQTYLKKEVCLIP-FKFFDIDGNGKISVEELKRIFGRDDIENPLIDK 167 Query: 168 EVEKLMAGQE-DSNGCINYEAFVKHI 192 ++ L+ + + +G I++ F+ + Sbjct: 168 AIDSLLQEVDLNGDGEIDFHEFMLMM 193 Score = 31.2 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 22/68 (32%), Gaps = 8/68 (11%) Query: 58 FMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK---PRQEELNTKMMDFETF 114 F FD KI+ + R G++ + ++ + +DF F Sbjct: 135 FKFFDID--GNGKISVEELK---RIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEF 189 Query: 115 LPMLQHIS 122 + M+ Sbjct: 190 MLMMSKKK 197 >4ORC-B nrPDB Length = 170 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 61/155 (39%), Gaps = 16/155 (10%) Query: 44 IEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEE 103 F ++I+ + F D ++ + L L QNP V+ + Sbjct: 13 SHFDADEIKRLGKRFKKLDLDNS--GSLSVEEFMS-LPELQQNPLVQRVIDIFDTD---- 65 Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GE 162 +DF+ F+ + S D + R++D + +G + EL VL + G Sbjct: 66 -GNGEVDFKEFIEGVSQFSVKGDK--EQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGN 122 Query: 163 RLTEDEVEK-----LMAGQEDSNGCINYEAFVKHI 192 L + ++++ ++ +D +G I++E F + Sbjct: 123 NLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 >4YZB-A nrPDB Length = 491 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 64/159 (40%), Gaps = 21/159 (13%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQC-----------GDVLRALGQNPTQAEVLRV 95 T E+ E + F D+ + ++ + G+ + AL Q+ + EV +V Sbjct: 334 TNEETVELNKIFQRMDKN--GDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQV 391 Query: 96 LGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRH 155 L ++ F + + K + + +FD +G+G + +EL Sbjct: 392 LDAVDFDKNG-----FIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELAT 446 Query: 156 VLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIM 193 + + + +++A + +++G +++E F + ++ Sbjct: 447 IFGV--SEVDSETWRRVLAEVDRNNDGEVDFEEFRQMLL 483 >5E37-A nrPDB Length = 356 Score = 64.3 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 66/168 (39%), Gaps = 14/168 (8%) Query: 32 PKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAE 91 P+ F+ + + + ++EE + F + D I + ++L ++ Sbjct: 11 PRAATFEG--LMDDASKAKMEELERRFKMADVD--GNGHIDREELRNLLESMESGEVYMM 66 Query: 92 VLRVLGKPRQEE-------LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEG 144 L + E ++ FE F ++ GT ++ + DK G Sbjct: 67 SQHWLPEDELERCMEQYDVNKDGVISFEEFKQII--YDGLLLEGTLAEYESAFKAVDKSG 124 Query: 145 NGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKH 191 NGT+ EL + A+LG ++ +++ LM + D +G I + F+ Sbjct: 125 NGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLM 172 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 14/94 (14%) Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL--GER------ 163 TF ++ SK K E+ ++ D +GNG + ELR++L ++ GE Sbjct: 14 ATFEGLMDDASKAKM----EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQH 69 Query: 164 -LTEDEVEKLMAGQE-DSNGCINYEAFVKHIMSS 195 L EDE+E+ M + + +G I++E F + I Sbjct: 70 WLPEDELERCMEQYDVNKDGVISFEEFKQIIYDG 103 Score = 28.9 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 17/125 (13%), Positives = 45/125 (36%), Gaps = 12/125 (9%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVL-RALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 +E + +D + I++ + ++ L T AE ++ + Sbjct: 74 DELERCMEQYDVNK--DGVISFEEFKQIIYDGLLLEGTLAEYESAF--KAVDKSGNGTIG 129 Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAE----LRHVLATLGERLTE 166 + + + E V+ ++++DK+ +G + E R+ L L + T Sbjct: 130 ATELSKLFASLGN---PVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTY 186 Query: 167 DEVEK 171 +++ Sbjct: 187 MTLDE 191 >1JC2-A nrPDB Length = 76 Score = 64.3 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Query: 122 SKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSN 180 ++ + E+ R+FDK +G + EL +L GE + E+++E LM + +++ Sbjct: 1 MEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNND 60 Query: 181 GCINYEAFVKHI 192 G I+++ F+K + Sbjct: 61 GRIDFDEFLKMM 72 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 36/68 (52%), Gaps = 4/68 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE F +FD+ + I + G++LRA G++ + ++ ++ ++ N +DF Sbjct: 10 EELANCFRIFDKN--ADGFIDIEELGEILRATGEHVIEEDIEDLM--KDSDKNNDGRIDF 65 Query: 112 ETFLPMLQ 119 + FL M++ Sbjct: 66 DEFLKMME 73 >2K2I-A nrPDB Length = 79 Score = 63.9 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 41/71 (57%), Gaps = 1/71 (1%) Query: 123 KNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNG 181 K + T E+ ++ ++FD + G + L+ V LGE LT++E+++++ + D +G Sbjct: 3 KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDG 62 Query: 182 CINYEAFVKHI 192 ++ + F++ + Sbjct: 63 EVSEQEFLRIM 73 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 + + EE +AF LFD KI++ V + LG+N T E+ ++ + ++ Sbjct: 2 QKMSEKDTKEEILKAFKLFD--DDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRD 59 Query: 103 ELNTKMMDFETFLPMLQHIS 122 + + FL +++ S Sbjct: 60 --GDGEVSEQEFLRIMKKTS 77 >1OZS-A nrPDB Length = 73 Score = 60.9 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 22/65 (33%), Positives = 43/65 (66%), Gaps = 1/65 (1%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEA 187 + E+ + R+FDK +G + EL+ +L GE +TED++E+LM G ++++G I+Y+ Sbjct: 5 SEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDE 64 Query: 188 FVKHI 192 F++ + Sbjct: 65 FLEFM 69 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 34/68 (50%), Gaps = 4/68 (5%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE + F +FD+ + I + +L+A G+ T+ ++ ++ ++ N +D+ Sbjct: 7 EELSDLFRMFDKN--ADGYIDLEELKIMLQATGETITEDDIEELM--KDGDKNNDGRIDY 62 Query: 112 ETFLPMLQ 119 + FL ++ Sbjct: 63 DEFLEFMK 70 >2K7B-A nrPDB Length = 76 Score = 60.5 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 PE+IEE +EAF FD+ + I G+ +R +G PT+ E++ + + Sbjct: 4 LRPEEIEELREAFREFDKDK--DGYINCRDLGNCMRTMGYMPTEMELIELSQQINM--NL 59 Query: 106 TKMMDFETFLPMLQ 119 +DF+ F+ ++ Sbjct: 60 GGHVDFDDFVELMG 73 Score = 52.8 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 E+ E R FDK+ +G + +L + + T+G TE E+ +L + G ++++ FV Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFV 69 Query: 190 KHI 192 + + Sbjct: 70 ELM 72 >5B8I-B nrPDB Length = 171 Score = 59.7 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 63/153 (41%), Gaps = 16/153 (10%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F E+++ + FM DR ++ D +L Q + R++ +E Sbjct: 15 FDHEEVDRLWKRFMKLDRDKSGTIE------RDEFLSLPQVSSNPLSTRMI--AIFDEDG 66 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-GERL 164 +DF+ F+ + + E +V+D + +G + EL VL + G L Sbjct: 67 GGDVDFQEFVS--GLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNL 124 Query: 165 TEDEVEK-----LMAGQEDSNGCINYEAFVKHI 192 + ++++ +M D +G I++E F + + Sbjct: 125 KDMQLQQIVDKTIMEADLDGDGRISFEEFTRMV 157 >4D1E-A nrPDB Length = 876 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 51/118 (43%), Gaps = 7/118 (5%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP 99 ++ T EQ+ EF+ +F FDR + + + L ++G + +AE R++ Sbjct: 726 TRDAKGITQEQMNEFRASFNHFDR--RKNGLMDHEDFRACLISMGYDLGEAEFARIM--T 781 Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 + + F++F+ + + DT T E + R+ + ++ ELR L Sbjct: 782 LVDPNGQGTVTFQSFIDFMTR--ETADTDTAEQVIASFRILASDKP-YILAEELRREL 836 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 116 PMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG 175 +L +K +F FD+ NG + + R L ++G L E E ++M Sbjct: 723 QILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTL 782 Query: 176 QE-DSNGCINYEAFVKHIM 193 + + G + +++F+ + Sbjct: 783 VDPNGQGTVTFQSFIDFMT 801 >1SJJ-A nrPDB Length = 863 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 7/118 (5%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP 99 ++ + EQ+ EF+ +F FDR K + L ++G N +AE R++ Sbjct: 713 TRDAKGISQEQMNEFRASFNHFDR--KKTGMMDCEDFRACLISMGYNMGEAEFARIMSIV 770 Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 + ++ F+ F+ + + DT T + + ++ + N + ELR L Sbjct: 771 --DPNRMGVVTFQAFIDFMSR--ETADTDTADQVMASFKILAGDKN-YITVDELRREL 823 >1JUO-A nrPDB Length = 198 Score = 55.9 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 15/133 (11%) Query: 61 FDRTPKCEMKITYGQCGDVLR----ALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLP 116 F + +I + L A G P E R++ + + M F F Sbjct: 39 FAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSM-LDRDMSGTMGFNEFKE 97 Query: 117 MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQ 176 + ++ + + FD + +GTV EL+ L T+G RL+ V +A + Sbjct: 98 LWAVLNG---------WRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNS-IAKR 147 Query: 177 EDSNGCINYEAFV 189 +NG I ++ ++ Sbjct: 148 YSTNGKITFDDYI 160 >5MRA-A nrPDB Length = 167 Score = 55.5 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 15/133 (11%) Query: 61 FDRTPKCEMKITYGQCGDVLR----ALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLP 116 F + +I + L A G P E R++ + + M F F Sbjct: 8 FAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSM-LDRDMSGTMGFNEFKE 66 Query: 117 MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQ 176 + ++ + + FD + +GTV EL+ L T+G RL+ V +A + Sbjct: 67 LWAVLNG---------WRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNS-IAKR 116 Query: 177 EDSNGCINYEAFV 189 +NG I ++ ++ Sbjct: 117 YSTNGKITFDDYI 129 >4GFT-A nrPDB Length = 69 Score = 55.5 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINY 185 D E+ ++ FD G + ++++++L T G+ LT+ E + + I+Y Sbjct: 2 DKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSED-NIDY 60 Query: 186 EAFVKHIM 193 + F + I+ Sbjct: 61 KLFCEDIL 68 >5OTJ-D nrPDB Length = 110 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 2/64 (3%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEA 187 +D + FD G+G + +EL L TLG + DEV+++MA + D +G I++ Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNE 59 Query: 188 FVKH 191 F+ Sbjct: 60 FISF 63 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 5/66 (7%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 ++ + F FD + KI+ + D LR LG + EV R++ + + +DF Sbjct: 3 DDMERIFKRFDTN--GDGKISLSELTDALRTLGST-SADEVQRMMAEIDTD--GDGFIDF 57 Query: 112 ETFLPM 117 F+ Sbjct: 58 NEFISF 63 >4ZCV-A nrPDB Length = 165 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 53/142 (37%), Gaps = 13/142 (9%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 EQ ++ F DR + + G+ + LR LG Q ++ + Sbjct: 8 DAEQPTRYETLFQALDRN--GDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDG- 64 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 +DFE F+ L + + DK +G + +E+ L TLG ++E Sbjct: 65 -KLDFEEFMKYL--------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISE 115 Query: 167 DEVEKLMAGQE-DSNGCINYEA 187 + E ++ + D +++ Sbjct: 116 QQAELILQSIDVDGTMTVDWNE 137 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 125 KDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGCI 183 +D + + D+ G+G V EL+ L LG L +D EK+ G + +G + Sbjct: 7 QDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKL 66 Query: 184 NYEAFVKHI 192 ++E F+K++ Sbjct: 67 DFEEFMKYL 75 >4N5X-A nrPDB Length = 199 Score = 54.7 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 53/142 (37%), Gaps = 13/142 (9%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNT 106 EQ ++ F DR + + G+ + LR LG Q ++ + Sbjct: 17 DAEQPTRYETLFQALDRN--GDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDG- 73 Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE 166 +DFE F+ L + + DK +G + +E+ L TLG ++E Sbjct: 74 -KLDFEEFMKYL--------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISE 124 Query: 167 DEVEKLMAGQE-DSNGCINYEA 187 + E ++ + D +++ Sbjct: 125 QQAELILQSIDVDGTMTVDWNE 146 Score = 45.8 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 1/70 (1%) Query: 124 NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM-AGQEDSNGC 182 ++D + + D+ G+G V EL+ L LG L +D EK+ G + +G Sbjct: 15 SQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGK 74 Query: 183 INYEAFVKHI 192 +++E F+K++ Sbjct: 75 LDFEEFMKYL 84 >2LVK-A nrPDB Length = 77 Score = 53.5 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFV 189 +D + FD G+G + +EL L TLG + DEV+++MA + D +G I++ F+ Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNEFI 60 Query: 190 KH 191 Sbjct: 61 SF 62 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 5/66 (7%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 ++ + F FD + KI+ + D LR LG + EV R++ + + +DF Sbjct: 2 DDMERIFKRFDTN--GDGKISLSELTDALRTLGST-SADEVQRMMAEIDTD--GDGFIDF 56 Query: 112 ETFLPM 117 F+ Sbjct: 57 NEFISF 62 >1Y1X-A nrPDB Length = 191 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 53/141 (37%), Gaps = 14/141 (9%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 +E E F D I+ + L + G + A ++L + + F Sbjct: 27 QELMEWFRAVDTD--GSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSG--EITF 82 Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 + F + I + EG R D G+G + E+R L + G +++E + Sbjct: 83 DEFKDLHHFILSMR---------EGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQA 133 Query: 172 LMAGQEDS-NGCINYEAFVKH 191 LM + G + ++ +V+ Sbjct: 134 LMRKFDRQRRGSLGFDDYVEL 154 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Query: 125 KDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCI 183 + ++ +E R D +G+G + EL L++ G + EKL+ + + +G I Sbjct: 21 RHMNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSGEI 80 Query: 184 NYEAF 188 ++ F Sbjct: 81 TFDEF 85 >1C7W-A nrPDB Length = 81 Score = 53.5 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG-ERLTEDEVEKLMAG-QEDSNGCIN 184 E+ + +VFD G+G + E + ++ +G E LT+ EVE+ M ED NG I+ Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVID 63 Query: 185 YEAFVKHI 192 F+ I Sbjct: 64 IPEFMDLI 71 Score = 34.3 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 35/78 (44%), Gaps = 5/78 (6%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNP-TQAEVLRVLGKPRQEELN 105 + EE AF +FD + I + + +++ +G+ P T AEV + + +E Sbjct: 3 RQDDEEEILRAFKVFDAN--GDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKE--ADEDG 58 Query: 106 TKMMDFETFLPMLQHISK 123 ++D F+ +++ Sbjct: 59 NGVIDIPEFMDLIKKSKN 76 Score = 29.7 bits (65), Expect = 0.83, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 27/58 (46%), Gaps = 2/58 (3%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 + ++DF+ F ++Q + + T + E ++ D++GNG + E ++ Sbjct: 17 FDANGDGVIDFDEFKFIMQKVGEEPLTDAEVE--EAMKEADEDGNGVIDIPEFMDLIK 72 >1H4B-A nrPDB Length = 84 Score = 53.2 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 2/69 (2%) Query: 124 NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGC 182 + + + FD G+G + AEL L TLG +T DEV+ +MA + D +G Sbjct: 2 DDHPQDKAERERIFKRFDANGDGKISAAELGEALKTLG-SITPDEVKHMMAEIDTDGDGF 60 Query: 183 INYEAFVKH 191 I+++ F Sbjct: 61 ISFQEFTDF 69 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 5/70 (7%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTK 107 P+ E + F FD + KI+ + G+ L+ LG + T EV ++ + + Sbjct: 5 PQDKAERERIFKRFDAN--GDGKISAAELGEALKTLG-SITPDEVKHMMAEIDTD--GDG 59 Query: 108 MMDFETFLPM 117 + F+ F Sbjct: 60 FISFQEFTDF 69 >1GJY-A nrPDB Length = 167 Score = 53.2 bits (126), Expect = 8e-08, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 51/133 (38%), Gaps = 15/133 (11%) Query: 61 FDRTPKCEMKITYGQCGDVLR----ALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLP 116 F + +I + L A G P E R++ + + M F F Sbjct: 8 FASVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSM-LDRDMSGTMGFNEFKE 66 Query: 117 MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQ 176 + ++ + + FD + +GTV EL+ L T+G RL V +A + Sbjct: 67 LWAVLNG---------WRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNS-IAKR 116 Query: 177 EDSNGCINYEAFV 189 ++G I ++ ++ Sbjct: 117 YSTSGKITFDDYI 129 >1QXP-A nrPDB Length = 900 Score = 52.8 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 61/159 (38%), Gaps = 27/159 (16%) Query: 46 FTPEQIEE-FKEAFMLFDRTPKCEMKITYGQCGDVL----------RALGQNPTQAEVLR 94 + E+I++ FK LF + +M+I+ + +L R G + Sbjct: 527 LSEEEIDDNFK---TLFSKLAGDDMEISVKELQTILNRIISKHKDLRTNGF--SLESCRS 581 Query: 95 VLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELR 154 ++ ++ + F + I ++ R FD + +G++ E+R Sbjct: 582 MVNLMDRD--GNGKLGLVEFNILWNRIRN---------YLTIFRKFDLDKSGSMSAYEMR 630 Query: 155 HVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 + G +L + ++A D I+++ FV+ ++ Sbjct: 631 MAIEAAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLV 669 Score = 42.8 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 64/160 (40%), Gaps = 19/160 (11%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVL-RALGQNPTQAEVLRVLGK 98 S I+ + E+ + F+ LF + +M+++ + ++L + + ++P + Sbjct: 720 SNIEANESEEERQ-FR---KLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDT 775 Query: 99 PRQ-----EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL 153 R + T + FE F + +I K + + F+ + +GT+ EL Sbjct: 776 CRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQGI---------YKRFETDRSGTIGSNEL 826 Query: 154 RHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 G L + ++ D G ++++ F+ ++ Sbjct: 827 PGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLV 866 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 26/85 (30%), Gaps = 12/85 (14%) Query: 66 KCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNK 125 I + A G + + ++ + +E MDF+ F+ L + Sbjct: 816 DRSGTIGSNELPGAFEAAGFHL-NQHIYSMIIRRYSDETGN--MDFDNFISCLVRL---- 868 Query: 126 DTGTYEDFVEGLRVFDKEGNGTVMG 150 + R DK G G + Sbjct: 869 -----DAMFRAFRSLDKNGTGQIQV 888 Score = 33.1 bits (74), Expect = 0.085, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 35/103 (33%), Gaps = 14/103 (13%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 +I + F FD ++ + + A G ++ + +EL + Sbjct: 604 NRIRNYLTIFRKFDLDKS--GSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDEL---I 658 Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 +DF+ F+ L + E + + D E GT+ Sbjct: 659 IDFDNFVRCLVRL---------EILFKIFKQLDPENTGTIQLD 692 >2OPO-A nrPDB Length = 86 Score = 52.8 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 121 ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DS 179 ++ D + FD G+G + +EL L TLG +T DEV ++MA + D Sbjct: 1 MAAEDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLG-SVTPDEVRRMMAEIDTDG 59 Query: 180 NGCINYEAFVKHIMSS 195 +G I+++ F ++ Sbjct: 60 DGFISFDEFTDFARAN 75 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 5/76 (6%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 + E TP+ I + + F FD + KI+ + GD L+ LG + T EV R++ + Sbjct: 1 MAAEDTPQDIADRERIFKRFDTN--GDGKISSSELGDALKTLG-SVTPDEVRRMMAEIDT 57 Query: 102 EELNTKMMDFETFLPM 117 + + F+ F Sbjct: 58 D--GDGFISFDEFTDF 71 >2JNX-A nrPDB Length = 134 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 19/127 (14%), Positives = 46/127 (36%), Gaps = 7/127 (5%) Query: 64 TPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISK 123 + ++Y + + + + P + E L L + +D F + + Sbjct: 10 DANGDGSVSYEEVKAFVSS--KRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFAAAVKE 67 Query: 124 NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG-ERLTEDEVEKLMAGQEDSNGC 182 + ++ D +G+G + E+ G E++ V+++M + +G Sbjct: 68 QDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGYEKV----VDQIMKADANGDGY 123 Query: 183 INYEAFV 189 I E F+ Sbjct: 124 ITLEEFL 130 Score = 31.2 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 26/57 (45%), Gaps = 3/57 (5%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM--AGQEDSNGCINYEAFVKH 191 + D G+G+V E++ + + +++ +L+ A D NG I+ F K Sbjct: 6 FKQLDANGDGSVSYEEVK-AFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKF 61 >3AAJ-A nrPDB Length = 167 Score = 50.8 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 57/139 (41%), Gaps = 23/139 (16%) Query: 57 AFMLFDRTPKCEMKITYGQCGDVLRALG----QNPTQAEVLRVLGKPRQEELNTKMMDFE 112 F D+ I+ + L + G NP V ++ +E N ++F Sbjct: 9 VFQRVDKDRS--GVISDTELQQAL-SNGTWTPFNPV--TVRSIISMFDRE--NKAGVNFS 61 Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKL 172 F + ++I+ D+ R +D++ +G + EL+ L+ G RL++ + L Sbjct: 62 EFTGVWKYIT---------DWQNVFRTYDRDNSGMIDKNELKQALS--GYRLSDQFHDIL 110 Query: 173 MAGQE-DSNGCINYEAFVK 190 + + G I ++ F++ Sbjct: 111 IRKFDRQGRGQIAFDDFIQ 129 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 13/102 (12%), Positives = 34/102 (33%), Gaps = 15/102 (14%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 I +++ F +DR I + L G + +L + + + + Sbjct: 70 ITDWQNVFRTYDRDNS--GMIDKNELKQALS--GYRLSDQ-FHDILIR-KFDRQGRGQIA 123 Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAE 152 F+ F+ + + + R +D + +G + + Sbjct: 124 FDDFI---------QGCIVLQRLTDIFRRYDTDQDGWIQVSY 156 >1F4Q-A nrPDB Length = 165 Score = 50.8 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 51/138 (36%), Gaps = 17/138 (12%) Query: 57 AFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQ-----AEVLRVLGKPRQEELNTKMMDF 111 + F + ++ + L G N T ++ ++ T M F Sbjct: 2 VYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDH--TGKMGF 59 Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK 171 F + ++ + E D++G+GTV ELR + +G RL+ + Sbjct: 60 NAFKELWAALNA---------WKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTT 110 Query: 172 LMAGQEDSNGCINYEAFV 189 ++ + NG I ++ +V Sbjct: 111 IVK-RYSKNGRIFFDDYV 127 >2BEC-A nrPDB Length = 202 Score = 50.8 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 33/176 (18%), Positives = 70/176 (39%), Gaps = 30/176 (17%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCE-MKITYGQCGDVLRALGQNPTQAEVLRVL 96 D+ + + F+ + F DR K ++ Q G AL NP ++ Sbjct: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIG----ALAVNPLGDRIIE-- 68 Query: 97 GKPRQEELNTKMMDFETFLPMLQ--HISKNKDTGTYE------------DFVEGLRVFDK 142 ++ +DF F+ +L +++DT T + +++D Sbjct: 69 ---SFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDL 125 Query: 143 EGNGTVMGAELRHVLATL-GERLTEDEVEKLM-----AGQEDSNGCINYEAFVKHI 192 + +G + E+ VL + G ++TE+++E + ED +G +++ F K + Sbjct: 126 DRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSL 181 Score = 37.0 bits (84), Expect = 0.006, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 29/68 (42%), Gaps = 5/68 (7%) Query: 57 AFMLFDRTPKCEMKITYGQCGDVLRAL-GQNPTQAEVLRVLGK--PRQEELNTKMMDFET 113 AF L+D + KI+ + VLR + G T+ ++ + + +E + F Sbjct: 119 AFQLYDLDR--DGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVE 176 Query: 114 FLPMLQHI 121 F L+ + Sbjct: 177 FTKSLEKM 184 >5ZGM-A nrPDB Length = 110 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 44/109 (40%), Gaps = 9/109 (8%) Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGT 147 T+ + K + D++ F ++ K++ E + DK+ +G Sbjct: 4 TKVLKADDINKAVSAFKDPGTFDYKRFFQLVGLKGKSEAQ-----VKEVFEILDKDQSGF 58 Query: 148 VMGAELRHVLATL---GERLTEDEVEKLMAG-QEDSNGCINYEAFVKHI 192 + EL+ VL G L++ E + L+A D +G I + F K + Sbjct: 59 IEEEELKSVLKGFSAHGRDLSDTETKALLAAGDSDHDGKIGADEFAKMV 107 >2N8Y-A nrPDB Length = 153 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 32/154 (20%), Positives = 61/154 (39%), Gaps = 25/154 (16%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQN-----PTQAEVLRVLGKPR 100 + EQ+ EF+ +F FDR + + L +LG + +AE R++ Sbjct: 4 ISQEQMNEFRASFNHFDRDHS--GTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVD 61 Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 L ++ F+ F+ + + DT T + + ++ + N + ELR Sbjct: 62 PNRLG--VVTFQAFIDFMSR--ETADTDTADQVMASFKILAGDKN-YITMDELRR----- 111 Query: 161 GERLTEDEVEKLMA------GQEDSNGCINYEAF 188 L D+ E +A G + G ++Y +F Sbjct: 112 --ELPPDQAEYCIARMAPYTGPDSVPGALDYMSF 143 >2GGZ-A nrPDB Length = 211 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 47/119 (39%), Gaps = 12/119 (10%) Query: 83 LGQNPTQAEVLRVLGKP--RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVF 140 LG + + + + + +DF F+ + I + K + +++ Sbjct: 46 LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK---MEQKLKWYFKLY 102 Query: 141 DKEGNGTVMGAELRHVLATL-----GERLTEDEVEKLM--AGQEDSNGCINYEAFVKHI 192 D +GNG++ EL + + + L+ +E L+ +++G + E F+ + Sbjct: 103 DADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 161 >1JF0-A nrPDB Length = 195 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 30/155 (19%), Positives = 57/155 (36%), Gaps = 15/155 (9%) Query: 51 IEEFKEAFMLFDRTPKCEMKIT---YGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN-- 105 I+ K F D ++ + D+ + LG P Q + + + Sbjct: 19 IKRHKFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLE 78 Query: 106 -TKMMDFETFLP--------MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 156 K F FL L ++N+ T E +FDK+G+GT+ E + Sbjct: 79 YGKETKFPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAY 138 Query: 157 LATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 G +E++ EK + D++G ++ + + Sbjct: 139 GRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTR 173 >1S36-A nrPDB Length = 195 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 57/157 (36%), Gaps = 19/157 (12%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQC-----GDVLRALGQNPTQAEVLRVLGKPRQEELN 105 I+ K F D KIT + D+ L P Q + +V + Sbjct: 19 IKRHKHMFDFLDIN--GNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCG 76 Query: 106 T---KMMDFETFLPMLQHIS-------KNKDTGTYEDFVEG-LRVFDKEGNGTVMGAELR 154 K + F FL + ++ + ++ + +FDK+G+GT+ E + Sbjct: 77 MEYGKEIAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWK 136 Query: 155 HVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 G ++++ E + D++G ++ + + Sbjct: 137 AYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTR 173 >5PAL-A nrPDB Length = 109 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 41/109 (37%), Gaps = 9/109 (8%) Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGT 147 T+ + K + D++ F ++ K E + DK+ +G Sbjct: 3 TKVLKADDINKAISAFKDPGTFDYKRFFHLVGLKGKTDAQ-----VKEVFEILDKDQSGF 57 Query: 148 VMGAELRHVLATL---GERLTEDEVEKLMAG-QEDSNGCINYEAFVKHI 192 + EL+ VL G L + E + L+A D +G I + F K + Sbjct: 58 IEEEELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIGADEFAKMV 106 >2R2I-A nrPDB Length = 198 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 63/159 (39%), Gaps = 16/159 (10%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKP 99 SK E + + ++ + F T ++T + +P+ + + + + Sbjct: 5 SKAVEELSATECHQWYKKF----MTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFET 60 Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + +DF ++ L + K K + +++D +GNG + EL +++ Sbjct: 61 -FDFNKDGYIDFMEYVAALSLVLKGK---VDQKLRWYFKLYDVDGNGCIDRGELLNIIKA 116 Query: 160 L------GERLTEDEVEKLM--AGQEDSNGCINYEAFVK 190 + E +T +E ++ + +G ++ E F++ Sbjct: 117 IRAINRCNEAMTAEEFTNMVFDKIDINGDGELSLEEFME 155 Score = 35.0 bits (79), Expect = 0.020, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 33/98 (33%), Gaps = 3/98 (3%) Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 K E + + F + + Y + + FD +G + E L Sbjct: 21 KKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVE--QMFETFDFNKDGYIDFMEYVAAL 78 Query: 158 ATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 + + + + ++ + D NGCI+ + I + Sbjct: 79 SLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKA 116 >1KFX-S nrPDB Length = 184 Score = 48.1 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 62/157 (39%), Gaps = 15/157 (9%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVL-RALGQNPTQAEVLRVLGKPRQ 101 + EE ++ LF + +M+++ + ++L + + ++P + R Sbjct: 3 YSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRS 62 Query: 102 -----EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 156 + T + FE F + +I + + + FD + +GT+ +EL Sbjct: 63 MVAVMDSDTTGKLGFEEFKYLWNNIKRWQAI---------YKQFDTDRSGTICSSELPGA 113 Query: 157 LATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 G L E ++ D +G ++++ F+ ++ Sbjct: 114 FEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLV 150 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 34/100 (34%), Gaps = 14/100 (14%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 I+ ++ + FD I + A G + + ++ + +E MD Sbjct: 87 IKRWQAIYKQFDTDRS--GTICSSELPGAFEAAGFHL-NEHLYNMIIRRYSDESGN--MD 141 Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMG 150 F+ F+ L + + + DK+G G + Sbjct: 142 FDNFISCLVRL---------DAMFRAFKSLDKDGTGQIQV 172 >2M1U-A nrPDB Length = 93 Score = 48.1 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 116 PMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG 175 ++ S D T +E FD + +G V E R ++ G +TE E+ + Sbjct: 13 GLVPRGSHMSDEKTQ--LIEAFYNFDGDYDGFVSVEEFRGIIRD-GLPMTEAEITEFFEA 69 Query: 176 QEDSN-GCINYEAFVKHIMS 194 + +N G I+Y+AF + S Sbjct: 70 ADPNNTGFIDYKAFAAMLYS 89 >3E3R-A nrPDB Length = 204 Score = 47.8 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 36/164 (21%), Positives = 52/164 (31%), Gaps = 33/164 (20%) Query: 58 FMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPM 117 F DR + + L LG QAE V K + + +D E FL Sbjct: 43 FRQLDRDGSRS--LDADEFRQGLAKLGLVLDQAEAEGVCRKW--DRNGSGTLDLEEFLRA 98 Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER------LTEDEVEK 171 L+ D+ G+G V +LR V + TEDEV + Sbjct: 99 LRPPM---SQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLR 155 Query: 172 LMAGQEDS---NGCI------NY-----------EAFVKHIMSS 195 DS +G + +Y E FV + S+ Sbjct: 156 RFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMTSA 199 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 40/93 (43%), Gaps = 1/93 (1%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + L + M + + L+ ++ + R D++G+ ++ E R LA L Sbjct: 7 RGPLGSHMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDRDGSRSLDADEFRQGLAKL 66 Query: 161 GERLTEDEVEKLMAG-QEDSNGCINYEAFVKHI 192 G L + E E + + +G ++ E F++ + Sbjct: 67 GLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRAL 99 >2D58-A nrPDB Length = 107 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKL 172 FL ++ S E F E FD GNG + L+ +L LG T E++KL Sbjct: 14 QFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKL 73 Query: 173 MAGQEDSNGC-INYEAFVKHIM 193 + +G +Y F++ ++ Sbjct: 74 IGEVSSGSGETFSYPDFLRMML 95 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D E P ++E FKE +M FD + I +L LG T E+ +++G Sbjct: 18 DPKYSSDEDLPSKLEGFKEKYMEFDLNGNGD--IDIMSLKRMLEKLGVPKTHLELKKLIG 75 Query: 98 KPRQEELNTKMMDFETFLPML 118 + + + + FL M+ Sbjct: 76 EVSSG--SGETFSYPDFLRMM 94 >1JFJ-A nrPDB Length = 134 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 18/129 (13%), Positives = 46/129 (35%), Gaps = 7/129 (5%) Query: 64 TPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISK 123 + ++Y + + + ++L+++ K + +D F I Sbjct: 10 DVNGDGAVSYEEVK-AFVSKKRAIKNEQLLQLIFK-SIDADGNGEIDQNEFAKFYGSIQG 67 Query: 124 NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG-ERLTEDEVEKLMAGQEDSNGC 182 + ++ D +G+G + E+ G E++ E++M + +G Sbjct: 68 QDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVA----EQVMKADANGDGY 123 Query: 183 INYEAFVKH 191 I E F++ Sbjct: 124 ITLEEFLEF 132 >1S6J-A nrPDB Length = 87 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 + ++ G ++ ++ D + +GT+ EL+ L +G L E E++ LM + Sbjct: 13 MAERLSEEEIGGLKEL---FKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAAD 69 Query: 178 -DSNGCINYEAFV 189 D +G I+Y F+ Sbjct: 70 IDKSGTIDYGEFI 82 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 4/79 (5%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D + + E+I KE F + D IT+ + D L+ +G ++E+ ++ Sbjct: 9 DDKHMAERLSEEEIGGLKELFKMIDTDNS--GTITFDELKDGLKRVGSELMESEIKDLMD 66 Query: 98 KPRQEELNTKMMDFETFLP 116 ++ T +D+ F+ Sbjct: 67 AADIDKSGT--IDYGEFIA 83 >3DF0-A nrPDB Length = 714 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 57/141 (40%), Gaps = 15/141 (10%) Query: 59 MLFDRTPKCEMKITYGQCGDVLRAL--GQNPTQAEVLRV----LGKPRQEELNTKMMDFE 112 LF + + +I+ + +LR + + +++ + + +E + + + Sbjct: 536 RLFAQLAGEDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLK 595 Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKL 172 F + I K + + R D + +GT+ E+R L G +L + + Sbjct: 596 EFYILWTKIQK---------YQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVI 646 Query: 173 MAGQEDSNGCINYEAFVKHIM 193 +A D I+++ FV+ ++ Sbjct: 647 VARFADDELIIDFDNFVRCLV 667 Score = 31.2 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 36/103 (34%), Gaps = 14/103 (13%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 +I+++++ + D + + L G ++ + +EL + Sbjct: 602 TKIQKYQKIYREIDVDRS--GTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL---I 656 Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 +DF+ F+ L + E + + D E GT+ Sbjct: 657 IDFDNFVRCLVRL---------EILFKIFKQLDPENTGTIQLD 690 >2G2B-A nrPDB Length = 150 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 1/82 (1%) Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKL 172 FL ++ S E F E FD GNG + L+ +L LG T E++KL Sbjct: 33 QFLDDPKYSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKL 92 Query: 173 MAGQEDSNGC-INYEAFVKHIM 193 + +G +Y F++ ++ Sbjct: 93 IGEVSSGSGETFSYPDFLRMML 114 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 4/81 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D E P ++E FKE +M FD + I +L LG T E+ +++G Sbjct: 37 DPKYSSDEDLPSKLEGFKEKYMEFDLNGNGD--IDIMSLKRMLEKLGVPKTHLELKKLIG 94 Query: 98 KPRQEELNTKMMDFETFLPML 118 + + + + FL M+ Sbjct: 95 EVSSG--SGETFSYPDFLRMM 113 >3KPX-A nrPDB Length = 198 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 59/150 (39%), Gaps = 19/150 (12%) Query: 58 FMLFDRTPKCEMKITYGQC-----GDVLRALGQNPTQAEVLRVLGKPRQEELN---TKMM 109 F D KIT + D+ LG P Q + + + +++ K + Sbjct: 29 FNFLDIN--GNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKEV 86 Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEG--------LRVFDKEGNGTVMGAELRHVLATLG 161 +F F+ + ++K+ ++ +FDK+G+G++ E + G Sbjct: 87 EFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEWKTYGGISG 146 Query: 162 ERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 ++++ EK + D++G ++ + + Sbjct: 147 ICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 >2G9B-A nrPDB Length = 263 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 51/128 (39%), Gaps = 15/128 (11%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQ-------AEVLRVLGKPRQEEL 104 EEF + + +D I + + L+ L + + AE ++ K + Sbjct: 103 EEFMKTWRKYDTDHS--GFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL-FDSN 159 Query: 105 NTKMMDFETFLPM--LQHISKNKDTG---TYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 N ++ + +Q K G ++F + ++D++GNG + EL +L Sbjct: 160 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 219 Query: 160 LGERLTED 167 L E+ ++ Sbjct: 220 LCEKNKQE 227 Score = 28.5 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 19/43 (44%) Query: 118 LQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + T F E FD +G+G + G EL++++ L Sbjct: 3 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQEL 45 >3BOW-B nrPDB Length = 184 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 63/160 (39%), Gaps = 19/160 (11%) Query: 40 SKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVL-RALGQNPTQAEVLRVLGK 98 S I+ + E+ + F+ LF + +M+++ + ++L + + ++P + Sbjct: 4 SNIEANESEEERQ-FR---KLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDT 59 Query: 99 -----PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL 153 + T + FE F + +I K + + FD + +GT+ EL Sbjct: 60 CRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQGI---------YKRFDTDRSGTIGSNEL 110 Query: 154 RHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 G L + ++ D G ++++ F+ ++ Sbjct: 111 PGAFEAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLV 150 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 34/100 (34%), Gaps = 14/100 (14%) Query: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMD 110 I++++ + FD I + A G + + ++ + +E MD Sbjct: 87 IKKWQGIYKRFDTDRS--GTIGSNELPGAFEAAGFHL-NQHIYSMIIRRYSDETGN--MD 141 Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMG 150 F+ F+ L + + R DK G G + Sbjct: 142 FDNFISCLVRL---------DAMFRAFRSLDKNGTGQIQV 172 >5JOJ-A nrPDB Length = 97 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 5/65 (7%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK-----LMAGQEDSNGCINY 185 + E D +GNG + EL + L V + + G D +G I++ Sbjct: 12 MELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISF 71 Query: 186 EAFVK 190 + F+K Sbjct: 72 DEFIK 76 >5JOL-A nrPDB Length = 82 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 5/65 (7%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK-----LMAGQEDSNGCINY 185 + E D +GNG + EL + L V + + G D +G I++ Sbjct: 12 MELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISF 71 Query: 186 EAFVK 190 + F+K Sbjct: 72 DEFIK 76 >2L2E-A nrPDB Length = 190 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 55/130 (42%), Gaps = 8/130 (6%) Query: 65 PKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKN 124 K + K++ Q D++R+ + + E+ + ++ + ++ F + + Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFD--KKELQQWYKGFFKD-CPSGHLNKSEFQKIYKQFFPF 58 Query: 125 KDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL--ATLGERLTEDEVEKLMAGQEDSNGC 182 D + ++V VFD + NG + E L + GE L + + D+NG Sbjct: 59 GDPSAFAEYV--FNVFDADKNGYIDFKEFICALSVTSRGE-LNDKLIWAFQLYDLDNNGL 115 Query: 183 INYEAFVKHI 192 I+Y+ ++ + Sbjct: 116 ISYDEMLRIV 125 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 42/103 (40%), Gaps = 16/103 (15%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL--- 157 + +DF+ F+ L S+ + + +++D + NG + E+ ++ Sbjct: 72 FDADKNGYIDFKEFICALSVTSRGELNDK---LIWAFQLYDLDNNGLISYDEMLRIVDAI 128 Query: 158 -ATLGE--RLTEDE------VEKLMAGQE-DSNGCINYEAFVK 190 +G +L EDE V K+ + + +G + E F + Sbjct: 129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 >1DGU-A nrPDB Length = 183 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 46/113 (40%), Gaps = 13/113 (11%) Query: 92 VLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 + + + FE FL +L S + R+FD + +GT+ Sbjct: 61 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHY--AFRIFDFDDDGTLNRE 118 Query: 152 ELRHV---LATLGE--RLTEDEVEKLM-----AGQEDSNGCINYEAFVKHIMS 194 +L + L GE RL+ E+++L+ D +G IN F +H++S Sbjct: 119 DLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF-QHVIS 170 >5I2L-A nrPDB Length = 120 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 41/103 (39%), Gaps = 4/103 (3%) Query: 28 EPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNP 87 EP+ P F+ EF+ +QI++ ++ F +D + I + ++ LG Sbjct: 7 EPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYD--AGRDGFIDLMELKLMMEKLGAPQ 64 Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTY 130 T + ++ + ++ + F FL + + + + Sbjct: 65 THLGLKNMIKEVDED--FDSKLSFREFLLIFRKAAAGELQEDS 105 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 30/68 (44%), Gaps = 1/68 (1%) Query: 123 KNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAG-QEDSNG 181 K +D + + +D +G + EL+ ++ LG T ++ ++ ED + Sbjct: 23 KEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDS 82 Query: 182 CINYEAFV 189 +++ F+ Sbjct: 83 KLSFREFL 90 >2JUL-A nrPDB Length = 256 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 22/194 (11%), Positives = 62/194 (31%), Gaps = 23/194 (11%) Query: 13 AKAAPKAAPAPAPPPEPE--RPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMK 70 + AAP+ + + E R + D + + +FT ++++ F + Sbjct: 53 SSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGF----KNECPTGL 108 Query: 71 ITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTY 130 + + A + + FE F ++ + T + Sbjct: 109 VDEDTFKLIYSQF-FPQGDATTYAHFLFNAFDADGNGAIHFEDF--VVGLSILLRGTV-H 164 Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTE------------DEVEKLM-AGQE 177 E ++D +G + E+ ++ ++ + + + VE+ Sbjct: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 Query: 178 DSNGCINYEAFVKH 191 + +G + + F++ Sbjct: 225 NQDGVVTIDEFLET 238 >5CUY-A nrPDB Length = 414 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 33/103 (32%), Gaps = 15/103 (14%) Query: 86 NPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGN 145 P Q V R + + + ++ + FD Sbjct: 49 EPIQEAVDRKVSELDLAAYDKDDFTQPMIKKIMSRL---------------FSAFDVTHL 93 Query: 146 GTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAF 188 G + ++ V LG +++ +V+ + A +G + +E F Sbjct: 94 GYLTPDKVEEVCRYLGRNMSDGDVKAMKAEINAIDGHVTFEKF 136 >2LM5-A nrPDB Length = 214 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 46/113 (40%), Gaps = 13/113 (11%) Query: 92 VLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 + + + FE FL +L S + R+FD + +GT+ Sbjct: 92 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHY--AFRIFDFDDDGTLNRE 149 Query: 152 ELRHV---LATLGE--RLTEDEVEKLM-----AGQEDSNGCINYEAFVKHIMS 194 +L + L GE RL+ E+++L+ D +G IN F +H++S Sbjct: 150 DLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF-QHVIS 201 >2E30-A nrPDB Length = 195 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 67/180 (37%), Gaps = 27/180 (15%) Query: 39 ASKIKIEFTPEQIEEFKE----AFMLFDRTPKCEMKITYGQCGDVLRA-------LGQNP 87 S+ E++EE K+ + R + G+ G + R L NP Sbjct: 2 GSRASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINP 61 Query: 88 TQAEVLRVLGKPRQEELNTKMM--DFETFLPMLQHISKNKDTGTYEDFVE-------GLR 138 ++ ++++N + F P+ + K+KD E R Sbjct: 62 LGDRIINAFFPEGEDQVNFRGFMRTLAHFRPI-EDNEKSKDVNGPEPLNSRSNKLHFAFR 120 Query: 139 VFDKEGNGTVMGAELRHVLATL-GERLTEDEV-----EKLMAGQEDSNGCINYEAFVKHI 192 ++D + + + EL VL + G ++++++ + +D + I++ FVK + Sbjct: 121 LYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVL 180 >5T7C-A nrPDB Length = 193 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 41/103 (39%), Gaps = 16/103 (15%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + +DF F+ L S+ K + ++D +GNG + +E+ ++ + Sbjct: 72 FDTNGDGTIDFREFIIALSVTSRGK---LEQKLKWAFSMYDLDGNGYISRSEMLEIVQAI 128 Query: 161 ------------GERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 E E +K+ + +++G ++ E F++ Sbjct: 129 YKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIR 171 Score = 32.7 bits (73), Expect = 0.11, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 36/90 (40%), Gaps = 3/90 (3%) Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 T + + F + + D + + V R FD G+GT+ E L+ Sbjct: 40 TGHLTVDEFKKIYANFFPYGDASKFAEHV--FRTFDTNGDGTIDFREFIIALSVTSRGKL 97 Query: 166 EDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E +++ + + D NG I+ ++ + + Sbjct: 98 EQKLKWAFSMYDLDGNGYISRSEMLEIVQA 127 >1KFU-L nrPDB Length = 699 Score = 44.3 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 28/180 (15%), Positives = 61/180 (33%), Gaps = 37/180 (20%) Query: 37 FDASKIKIEFTPEQIEEFKEAFM------------LFDRTPKCEMKITYGQCGDVLRALG 84 F K + ++IE E F LF + + +I+ + +LR Sbjct: 501 FSEKKADYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQLAGEDAEISAFELQTILRR-- 558 Query: 85 QNPTQAEVLRVLGKPRQ-----------EELNTKMMDFETFLPMLQHISKNKDTGTYEDF 133 A+ + + + + + F + I K + Sbjct: 559 ---VLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK---------Y 606 Query: 134 VEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 + R D + +GT+ E+R L G ++ + ++A D I+++ FV+ ++ Sbjct: 607 QKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLV 666 Score = 29.7 bits (65), Expect = 0.81, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 36/103 (34%), Gaps = 14/103 (13%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 +I+++++ + D + + L G ++ + ++L + Sbjct: 601 TKIQKYQKIYREIDVDRS--GTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQL---I 655 Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 +DF+ F+ L + E + + D E GT+ Sbjct: 656 IDFDNFVRCLVRL---------ETLFKIFKQLDPENTGTIELD 689 >1V1G-A nrPDB Length = 222 Score = 43.9 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 63/176 (35%), Gaps = 19/176 (10%) Query: 26 PPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQ 85 PP E P+ + FT E++E E F + + I + AL + Sbjct: 16 PPGYEDPELLA-----SVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQL---ALFR 67 Query: 86 NPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGN 145 N + + + +++F F+ L + +E +++D Sbjct: 68 NRNRRNLFADRIFDVFDVKRNGVIEFGEFVRSLGVF--HPSAPVHEKVKFAFKLYDLRQT 125 Query: 146 GTVMGAELRHVLATLGER----LTEDEVEKLMA-----GQEDSNGCINYEAFVKHI 192 G + EL+ ++ L L+ED +E ++ ++G I+ + + + Sbjct: 126 GFIEREELKEMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFV 181 >1BJF-A nrPDB Length = 193 Score = 43.1 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 40/103 (38%), Gaps = 16/103 (15%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + +DF F+ L S+ K + ++D +GNG + AE+ ++ + Sbjct: 72 FDANGDGTIDFREFIIALSVTSRGK---LEQKLKWAFSMYDLDGNGYISKAEMLEIVQAI 128 Query: 161 ------------GERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 E E EK+ + + +G ++ E F++ Sbjct: 129 YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIR 171 Score = 32.4 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 42/108 (38%), Gaps = 4/108 (3%) Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGT 147 T+ E+ ++ + + E F + + D + + V R FD G+GT Sbjct: 23 TEHEIQEWYKGFLRD-CPSGHLSMEEFKKIYGNFFPYGDASKFAEHV--FRTFDANGDGT 79 Query: 148 VMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 + E L+ E +++ + + D NG I+ ++ + + Sbjct: 80 IDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQA 127 >1WY9-A nrPDB Length = 147 Score = 43.1 bits (100), Expect = 8e-05, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKL 172 FL ++ + E F FD GNG + L+ +L LG T E+++L Sbjct: 30 QFLDDPKYSNDEDLPSKLEAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRL 89 Query: 173 MAGQEDSNGC-INYEAFVKHIM 193 + + +Y F++ ++ Sbjct: 90 IREVSSGSEETFSYSDFLRMML 111 Score = 33.1 bits (74), Expect = 0.079, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 32/81 (39%), Gaps = 4/81 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D E P ++E FK +M FD + I +L LG T E+ R++ Sbjct: 34 DPKYSNDEDLPSKLEAFKVKYMEFDLNGNGD--IDIMSLKRMLEKLGVPKTHLELKRLIR 91 Query: 98 KPRQEELNTKMMDFETFLPML 118 + + + + FL M+ Sbjct: 92 EVSSG--SEETFSYSDFLRMM 110 >2JU0-A nrPDB Length = 190 Score = 42.8 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 14/107 (13%), Positives = 33/107 (30%), Gaps = 13/107 (12%) Query: 58 FMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPM 117 F +FD+ I + + VL + + ++ + F+ L + Sbjct: 69 FTVFDKDNN--GFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGY--ITFDEMLTI 124 Query: 118 LQHISK---------NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRH 155 + + K + + ++ DK +G + E R Sbjct: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 39/91 (42%), Gaps = 5/91 (5%) Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVE-GLRVFDKEGNGTVMGAELRHVLATLGERL 164 + + E F+ + + G+ EDF VFDK+ NG + E VL+T Sbjct: 40 SGQLAREDFVKIYKQFFPF---GSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGT 96 Query: 165 TEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 E+++ + + +G I ++ + + S Sbjct: 97 LEEKLSWAFELYDLNHDGYITFDEMLTIVAS 127 >5C5V-A nrPDB Length = 342 Score = 42.8 bits (99), Expect = 9e-05, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 23/56 (41%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAF 188 FD G + ++ V LG +++ +V+ + A +G + +E F Sbjct: 9 MSRLFSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKAMKAEINAIDGHVTFEKF 64 >2VTG-A nrPDB Length = 150 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 33/82 (40%), Gaps = 1/82 (1%) Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKL 172 FL ++ + F E FD G + L+ ++ LG T E++K+ Sbjct: 32 EFLCDQKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKM 91 Query: 173 MAGQEDS-NGCINYEAFVKHIM 193 ++ + I+Y FV ++ Sbjct: 92 ISEVTGGVSDTISYRDFVNMML 113 Score = 34.7 bits (78), Expect = 0.025, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Query: 38 DASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLG 97 D E PE++ FKE +M FD + E I ++ LG T E+ +++ Sbjct: 36 DQKYSDEENLPEKLTAFKEKYMEFDLNNEGE--IDLMSLKRMMEKLGVPKTHLEMKKMIS 93 Query: 98 KPRQEELNTKMMDFETFLPML 118 + +T + + F+ M+ Sbjct: 94 EVTGGVSDT--ISYRDFVNMM 112 >5XND-A nrPDB Length = 114 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 28/68 (41%), Gaps = 4/68 (5%) Query: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATL---GERLTEDEVEKLMAG-QEDSNGCIN 184 + ++ + + D++ +G + EL+ L L++ E + + D +G I Sbjct: 45 STDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKIG 104 Query: 185 YEAFVKHI 192 + F I Sbjct: 105 IDEFAAMI 112 Score = 26.6 bits (57), Expect = 7.9, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 28/77 (36%), Gaps = 7/77 (9%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVL---RALGQNPTQAEVLRVLGKPRQE 102 + + +E K+AF + D+ I + L +A + + AE L + Sbjct: 41 LSGKSTDEVKKAFAIIDQDKS--GFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSD 98 Query: 103 ELNTKMMDFETFLPMLQ 119 + + F M++ Sbjct: 99 --GDGKIGIDEFAAMIK 113 >5M6C-E nrPDB Length = 193 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 42/103 (40%), Gaps = 16/103 (15%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + + +DF F+ L S+ + + + ++D +GNG + E+ ++ + Sbjct: 72 FDTNSDGTIDFREFIIALSVTSRGR---LEQKLMWAFSMYDLDGNGYISREEMLEIVQAI 128 Query: 161 ------------GERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 E E EK+ + +++G ++ E F++ Sbjct: 129 YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIR 171 Score = 30.0 bits (66), Expect = 0.60, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 37/90 (41%), Gaps = 3/90 (3%) Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA-TLGERL 164 T +++ + F + + D + + V R FD +GT+ E L+ T RL Sbjct: 40 TGILNVDEFKKIYANFFPYGDASKFAEHV--FRNFDTNSDGTIDFREFIIALSVTSRGRL 97 Query: 165 TEDEVEKLMAGQEDSNGCINYEAFVKHIMS 194 + + D NG I+ E ++ + + Sbjct: 98 EQKLMWAFSMYDLDGNGYISREEMLEIVQA 127 >1SL8-A nrPDB Length = 191 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 20/151 (13%), Positives = 51/151 (33%), Gaps = 15/151 (9%) Query: 55 KEAFMLFDRTPKCEMKIT---YGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTK---M 108 K F D + + Y V+ LG P QA+ + + K Sbjct: 19 KHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMKYGVE 78 Query: 109 MDFETFLPMLQHISKN---KDTGTYEDFVEG-----LRVFDKEGNGTVMGAELRHVLATL 160 ++ ++ + ++ + + + + DK+ NG + E + + Sbjct: 79 TEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTKSA 138 Query: 161 GERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 G + ++ E+ + D +G ++ + + Sbjct: 139 GIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >1TIZ-A nrPDB Length = 67 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 24/60 (40%), Gaps = 1/60 (1%) Query: 134 VEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 FDK +G + E R V T++++ K + D NG +N + F I Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSCI 63 >1NP8-A nrPDB Length = 159 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 60/151 (39%), Gaps = 15/151 (9%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVL-RALGQNPTQAEVLRVLGKPRQ-----E 102 + EE ++ LF + +M+++ + ++L + + ++P + R + Sbjct: 5 NESEEERQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMD 64 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 162 T + FE F + +I K + + FD + +GT+ EL G Sbjct: 65 SDTTGKLGFEEFKYLWNNIKKWQGI---------YKRFDTDRSGTIGSNELPGAFEAAGF 115 Query: 163 RLTEDEVEKLMAGQEDSNGCINYEAFVKHIM 193 L + ++ D G ++++ F+ ++ Sbjct: 116 HLNQHIYSMIIRRYSDETGNMDFDNFISCLV 146 >4OKH-A nrPDB Length = 189 Score = 42.0 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 21/153 (13%), Positives = 57/153 (37%), Gaps = 26/153 (16%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRAL----------GQNPTQAEVLRVLG 97 E+ ++F+ +F + +M+I + VL + G T ++ Sbjct: 8 SEEQQQFR---NIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGF--TLESCRSMIA 62 Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 + + ++ + F + I + + + +D + +GT+ E+R+ + Sbjct: 63 LMDTD--GSGKLNLQEFHHLWNKIKA---------WQKIFKHYDTDQSGTINSYEMRNAV 111 Query: 158 ATLGERLTEDEVEKLMAGQEDSNGCINYEAFVK 190 G L + + D + I++++F+ Sbjct: 112 NDAGFHLNNQLYDIITMRYADKHMNIDFDSFIC 144 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 41/112 (36%), Gaps = 14/112 (12%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 +I+ +++ F +D I + + + G + + + + +N Sbjct: 82 NKIKAWQKIFKHYDTDQS--GTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMN--- 136 Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 +DF++F+ + E FDK+G+G + L + T+ Sbjct: 137 IDFDSFICCFVRL---------EGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 179 >2KQY-A nrPDB Length = 108 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 36/95 (37%), Gaps = 9/95 (9%) Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 ++++F + SK D + + D++ +G + EL+ L Sbjct: 19 QAADSFNYKSFFSTVGLSSKTPDQ-----IKKVFGILDQDKSGFIEEEELQLFLKNFSSS 73 Query: 164 ---LTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 LT E + +A + D +G I E F + + Sbjct: 74 ARVLTSAETKAFLAAGDTDGDGKIGVEEFQSLVKA 108 >2NA0-A nrPDB Length = 205 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 41/101 (40%), Gaps = 12/101 (11%) Query: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 + +DF + L + K K + +++D +GNG + EL ++ Sbjct: 61 ETFDFNKDGYIDFMEYEAALSLVLKGK---VEQKLRWYFKLYDVDGNGCIDRDELLTIIR 117 Query: 159 TL-------GERLTEDEV-EKLMAGQE-DSNGCINYEAFVK 190 + +T +E + + + + + +G ++ E F++ Sbjct: 118 AIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFME 158 Score = 34.3 bits (77), Expect = 0.039, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 34/98 (34%), Gaps = 3/98 (3%) Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 K E + + F + + Y + + FD +G + E L Sbjct: 23 KKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVE--QMFETFDFNKDGYIDFMEYEAAL 80 Query: 158 ATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 + + + E ++ + D NGCI+ + + I + Sbjct: 81 SLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRA 118 >1UHK-A nrPDB Length = 191 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 22/151 (14%), Positives = 47/151 (31%), Gaps = 15/151 (9%) Query: 55 KEAFMLFDRTPKCEMKIT---YGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 K F D ++ + Y V+ LG P QA+ + + K Sbjct: 19 KHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMKYGVE 78 Query: 112 ETFLPMLQHISK------NKDTGTYEDFVE-----GLRVFDKEGNGTVMGAELRHVLATL 160 + ++ K K + + DK+ NG + E + Sbjct: 79 TDWPAYIEGWKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKAA 138 Query: 161 GERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 G + ++ E+ + D +G ++ + + Sbjct: 139 GIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >5CUU-A nrPDB Length = 414 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 25/56 (44%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAF 188 FD G + ++ H+ LG + ED+V+++ + +G I +E F Sbjct: 80 MARMFSAFDVTQLGYLEERKIEHMCKYLGRVMNEDDVKQMKSEINAIDGHITFEKF 135 >2KYF-A nrPDB Length = 108 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 36/87 (41%), Gaps = 4/87 (4%) Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA--TLGER-LTEDE 168 ++F P + E R+ D + +G + EL++ L G R LT E Sbjct: 22 DSFSPKKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASE 81 Query: 169 VEKLMAGQE-DSNGCINYEAFVKHIMS 194 + +A + D +G I E F + + S Sbjct: 82 TKTFLAAADHDGDGKIGAEEFQEMVQS 108 Score = 26.2 bits (56), Expect = 9.5, Method: Composition-based stats. Identities = 8/58 (13%), Positives = 21/58 (36%) Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + + ++ + LQ T + L D +G+G + E + ++ + Sbjct: 51 DNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHDGDGKIGAEEFQEMVQS 108 >4PAL-A nrPDB Length = 108 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATL---GERLTEDEVEKLMA-GQEDSNGCINYE 186 +D + V D++ +G + EL+ L LT+ E + +A G +D +G I + Sbjct: 41 DDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMIGVD 100 Query: 187 AFVKHIMS 194 F I + Sbjct: 101 EFAAMIKA 108 >1RTP-1 nrPDB Length = 109 Score = 40.8 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 9/89 (10%) Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL--- 160 D + F M+ K+ D D + + DK+ +G + EL +L Sbjct: 19 TAADSFDHKKFFQMVGLKKKSAD-----DVKKVFHILDKDKSGFIEEDELGSILKGFSSD 73 Query: 161 GERLTEDEVEKLMAG-QEDSNGCINYEAF 188 L+ E + LMA +D +G I E F Sbjct: 74 ARDLSAKETKTLMAAGDKDGDGKIGVEEF 102 >3PAT-A nrPDB Length = 110 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATL---GERLTEDEVEKLMAGQE-DSNGCINYEA 187 D + + D + +G + EL+ VL + G LT+ E + + + D +G I + Sbjct: 43 DVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDE 102 Query: 188 F 188 F Sbjct: 103 F 103 >1A75-A nrPDB Length = 108 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 28/68 (41%), Gaps = 4/68 (5%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELR---HVLATLGERLTEDEVEKLMAG-QEDSNGCINYE 186 +D + D++ +G + EL+ V LT+ E + + D +G I E Sbjct: 41 DDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGDSDGDGAIGVE 100 Query: 187 AFVKHIMS 194 +V + + Sbjct: 101 EWVALVKA 108 >2ZFD-A nrPDB Length = 226 Score = 40.4 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 55/160 (34%), Gaps = 20/160 (12%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F+ +IE E F + I + AL + + + + + Sbjct: 42 FSVSEIEALYELFKKISSAVIDDGLINKEEFQL---ALFKTNKKESLFADRVFDLFDTKH 98 Query: 106 TKMMDFETF---LPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV----LA 158 ++ FE F L + + D + +++D + G + E++ + LA Sbjct: 99 NGILGFEEFARALSVFHPNAPIDDKIHF-----SFQLYDLKQQGFIERQEVKQMVVATLA 153 Query: 159 TLGERLTEDEVEKLM-----AGQEDSNGCINYEAFVKHIM 193 G L + +E ++ +G I+ E + ++ Sbjct: 154 ESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 193 >1JBA-A nrPDB Length = 204 Score = 40.1 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 40/109 (36%), Gaps = 21/109 (19%) Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + +DF ++ L + + +++DK+ NG + EL ++ + Sbjct: 67 AFDTNGDNTIDFLEYVAALNLVLRG---TLEHKLKWTFKIYDKDRNGCIDRQELLDIVES 123 Query: 160 ----------------LGERLTEDEVEK--LMAGQEDSNGCINYEAFVK 190 G+ LT +EV + E+ +G ++ FV+ Sbjct: 124 IYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVE 172 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 34/96 (35%), Gaps = 4/96 (4%) Query: 98 KPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 157 K EE + + F + + T E R FD G+ T+ E L Sbjct: 29 KKFLEECPSGTLFMHEFKRFFKVPDNEEATQYVEAM---FRAFDTNGDNTIDFLEYVAAL 85 Query: 158 ATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + E +++ + D NGCI+ + + + Sbjct: 86 NLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIV 121 >6EPA-A nrPDB Length = 187 Score = 39.7 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 39/100 (39%), Gaps = 15/100 (15%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVL--- 157 +E N ++FE F+ L S+ E R++D + +G + E+ +++ Sbjct: 72 FDENNDGAIEFEEFIRALSITSRG---NLDEKLHWAFRLYDVDNDGYITREEMYNIVDAI 128 Query: 158 --------ATLGERLTEDEVEKLMAGQE-DSNGCINYEAF 188 T E + V+K+ + + + + E F Sbjct: 129 YQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEF 168 Score = 30.4 bits (67), Expect = 0.48, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 41/101 (40%), Gaps = 4/101 (3%) Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGT 147 T+ E+ + ++ N ++ + F+ + + + D + V RVFD+ +G Sbjct: 23 TEKEIRQWHKGFLKDCPN-GLLTEQGFIKIYKQFFPDGDPSKFASLV--FRVFDENNDGA 79 Query: 148 VMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEA 187 + E L+ ++++ + D++G I E Sbjct: 80 IEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 >4P5X-A nrPDB Length = 315 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 26/154 (16%), Positives = 55/154 (35%), Gaps = 28/154 (18%) Query: 53 EFKEAFMLFDRTP-KCEMKITYGQCGDVLRALGQ------NPTQAEVLRVLGKPRQEELN 105 E + F+ + T E +T V R LG NP ++L + ++ Sbjct: 19 ELRNIFLQYASTEVDGERYMTPEDF--VQRYLGLYNDPNSNPKIVQLLAGVADQTKD--- 73 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 ++ ++ FL + F+ ++FDK GNG V ++ + G+ + Sbjct: 74 -GLISYQEFLAFESVLCAPDSM-----FIVAFQLFDKSGNGEVTFENVKEIF---GQTII 124 Query: 166 EDEVE-----KLMAGQ--EDSNGCINYEAFVKHI 192 + + + + +NY F + + Sbjct: 125 HHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFL 158 Score = 36.2 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 39/108 (36%), Gaps = 16/108 (14%) Query: 57 AFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEV----LRVLGKPRQEELNTKMMDFE 112 AF LFD++ E +T+ ++ GQ + + K +++ Sbjct: 98 AFQLFDKSGNGE--VTFENVKEIF---GQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYT 152 Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 F LQ + E + + DK +G + G + ++ T+ Sbjct: 153 EFTQFLQEL-------QLEHARQAFALKDKSKSGMISGLDFSDIMVTI 193 >5CPV-A nrPDB Length = 109 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 28/68 (41%), Gaps = 4/68 (5%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATL---GERLTEDEVEKLMAG-QEDSNGCINYE 186 +D + + D++ +G + EL+ L LT+ E + + D +G I + Sbjct: 42 DDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGDSDGDGKIGVD 101 Query: 187 AFVKHIMS 194 F + + Sbjct: 102 EFTALVKA 109 >2M7L-A nrPDB Length = 144 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 58/151 (38%), Gaps = 20/151 (13%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNP------TQAEVLRVLGKPR 100 T EQ++EFK++F FD + + + L ++G A+ + Sbjct: 7 TAEQMQEFKQSFDAFD--GNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIYNNVT 64 Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + E + F+ ++ ++ KN + + E E G ++ +++ Sbjct: 65 KGENG---VSFDNYVQYMKE--KNDENPSPEQLNEIFSTI-AAGKDSITETDMQKA---- 114 Query: 161 GERLTEDEVEKLMAGQEDSNGCINYEAFVKH 191 ++ +++E + A +Y A+VK Sbjct: 115 --GMSAEQIEYVKANLPQKGDGYDYAAWVKT 143 >1RK9-A nrPDB Length = 110 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 36/89 (40%), Gaps = 9/89 (10%) Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL--- 160 T D + F M+ K+ D D + + DK+ +G + EL +L Sbjct: 20 SATDSFDHKKFFQMVGLKKKSAD-----DVKKVFHMLDKDKSGFIEEDELGFILKGFSPD 74 Query: 161 GERLTEDEVEKLMAG-QEDSNGCINYEAF 188 L+ E + LMA +D +G I + F Sbjct: 75 ARDLSAKETKMLMAAGDKDGDGKIGVDEF 103 >1BU3-A nrPDB Length = 109 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 37/92 (40%), Gaps = 9/92 (9%) Query: 107 KMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELR---HVLATLGER 163 +++ F + +K+ D D + V D++ +G + EL+ V + Sbjct: 23 DSFNYKAFFAKVGLTAKSAD-----DIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARA 77 Query: 164 LTEDEVEKLMAG-QEDSNGCINYEAFVKHIMS 194 LT+ E + + D +G I + + + + Sbjct: 78 LTDAETKAFLKAGDSDGDGAIGVDEWAALVKA 109 Score = 26.2 bits (56), Expect = 9.6, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 25/71 (35%), Gaps = 5/71 (7%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRAL---GQNPTQAEVLRVLGKP 99 K+ T + ++ K+AF + D+ I + L+ + T AE L Sbjct: 33 KVGLTAKSADDIKKAFFVIDQDKS--GFIEEDELKLFLQVFSAGARALTDAETKAFLKAG 90 Query: 100 RQEELNTKMMD 110 + +D Sbjct: 91 DSDGDGAIGVD 101 >2NLN-A nrPDB Length = 108 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 41/107 (38%), Gaps = 4/107 (3%) Query: 92 VLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 + +L + D +TF P + + + R D + +G + G Sbjct: 2 ITDILSAEDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGD 61 Query: 152 ELRHVLATL---GERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 EL++ L LTE E + LM + D +G I + F + + S Sbjct: 62 ELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEFQEMVHS 108 >1TTX-A nrPDB Length = 109 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 41/107 (38%), Gaps = 4/107 (3%) Query: 92 VLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGA 151 + VL + D +TF P + + + R D + +G + Sbjct: 3 ITDVLSADDIAAALQECRDPDTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEE 62 Query: 152 ELRHVLA---TLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 EL+ L + LTE E + LMA + D +G I E F + + S Sbjct: 63 ELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS 109 >1UHN-A nrPDB Length = 189 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 53/157 (33%), Gaps = 14/157 (8%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 F+ +IE E F + I + AL + + + + + Sbjct: 11 FSVSEIEALYELFKKISSAVIDDGLINKEEFQL---ALFKTNKKESLFADRVFDLFDTKH 67 Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV----LATLG 161 ++ FE F L N F +++D + G + E++ + LA G Sbjct: 68 NGILGFEEFARALSVFHPNAPIDDKIHF--SFQLYDLKQQGFIERQEVKQMVVATLAESG 125 Query: 162 ERLTEDEVEKLM-----AGQEDSNGCINYEAFVKHIM 193 L + +E ++ +G I+ E + ++ Sbjct: 126 MNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVL 162 >1QX2-A nrPDB Length = 76 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 36/69 (52%), Gaps = 5/69 (7%) Query: 129 TYEDFVEGLRVFD-KEGN-GTVMGAELRHVLATLGERLTE--DEVEKLMAGQE-DSNGCI 183 + E+ VF KEG+ + EL+ V+ TLG L + +++++ + + +G + Sbjct: 3 SPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEV 62 Query: 184 NYEAFVKHI 192 ++E F+ + Sbjct: 63 SFEEFLVMM 71 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 31/72 (43%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 EE K AF +F +I+ + V++ LG + + ++ + F Sbjct: 5 EEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEVSF 64 Query: 112 ETFLPMLQHISK 123 E FL M++ IS+ Sbjct: 65 EEFLVMMKKISQ 76 >3MSE-B nrPDB Length = 180 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 18/155 (11%), Positives = 53/155 (34%), Gaps = 21/155 (13%) Query: 49 EQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKM 108 I+ E F + +++ + VL ++G + ++ R+L + + Sbjct: 36 NHIKYINELF--YKLDTNHNGSLSHREIYTVLASVGIK--KWDINRIL--QALDINDRGN 89 Query: 109 MDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDE 168 + + F+ + T DK+ +G + +++ V + L ++ Sbjct: 90 ITYTEFMAGCYRWKNIESTF----LKAAFNKIDKDEDGYISKSDI--VSLVHDKVLDNND 143 Query: 169 VEKLMAGQEDSN---------GCINYEAFVKHIMS 194 ++ I+++ F +++S Sbjct: 144 IDNFFLSVHSIKKGIPREHIINKISFQEFKDYMLS 178 >5E1J-A nrPDB Length = 741 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 31/87 (35%), Gaps = 6/87 (6%) Query: 111 FETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAE---LRHVLATLGE--RLT 165 +++F L D + + D + NG + + L L +++ Sbjct: 305 YDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKIS 364 Query: 166 EDEVEKLMAGQEDS-NGCINYEAFVKH 191 ++E + +D+ + IN + F Sbjct: 365 KEEFGLIFDELDDTRDFKINKDEFADL 391 Score = 29.7 bits (65), Expect = 0.91, Method: Composition-based stats. Identities = 9/75 (12%), Positives = 25/75 (33%), Gaps = 2/75 (2%) Query: 102 EELNTKMMDFETFLPMLQHISKNKD--TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + +D + + + ++ + + E+F D + + E + Sbjct: 335 DSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQA 394 Query: 160 LGERLTEDEVEKLMA 174 + R ++EV L Sbjct: 395 IALRFQKEEVPSLFE 409 >5VE9-A nrPDB Length = 91 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKH 191 ++ R DK+ +G + E + T+ E+ + + D +G I+Y FV Sbjct: 29 VMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAA 88 Query: 192 I 192 + Sbjct: 89 L 89 Score = 30.4 bits (67), Expect = 0.53, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 85 QNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEG 144 N ++ V+ + +++ + + F + I +K T + +FD++G Sbjct: 22 MNHKKSRVMDFFRRIDKDQDG--KITRQEF---IDGILASKFPTTKLEMTAVADIFDRDG 76 Query: 145 NGTVMGAEL 153 +G + E Sbjct: 77 DGYIDYYEF 85 >5ZH6-A nrPDB Length = 107 Score = 37.7 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 28/68 (41%), Gaps = 8/68 (11%) Query: 133 FVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK------LMAGQEDSNGCINYE 186 + + D++ +G + EL+ L T E+++ L AG D +G I + Sbjct: 42 LAKVFDILDQDRSGFIEVDELKLFLQNF--SATARELDETETNAFLAAGDSDHDGKIGVD 99 Query: 187 AFVKHIMS 194 F + + Sbjct: 100 EFKAMVKA 107 >6DU8-A nrPDB Length = 805 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 43/126 (34%), Gaps = 16/126 (12%) Query: 41 KIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEV----LRVL 96 + + + E KE + + Q D+L+ G N T + RV Sbjct: 554 NMFLAIINDTYSEVKE---------ELAGQKDELQLSDLLKQ-GYNKTLLRLRLRKERVS 603 Query: 97 GKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 156 + + + + FE F L+ + + T + FD++GN + E + Sbjct: 604 DVQKVLQGGEQEIQFEDFTNTLRELGHAEHEIT--ELTATFTKFDRDGNRILDEKEQEKM 661 Query: 157 LATLGE 162 L E Sbjct: 662 RQDLEE 667 >5YPX-A nrPDB Length = 223 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 36/78 (46%), Gaps = 11/78 (14%) Query: 127 TGTYEDFVE-GLRVFDKEGNGTVMGAELRHVLAT-LGERLTEDEVEKLMAG--------- 175 GT ++ +E VFD G+G + E+ +L T L ++ TE++ ++ + Sbjct: 112 RGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKTCLVKQPTEEDPDEGIKDLVEIALKKM 171 Query: 176 QEDSNGCINYEAFVKHIM 193 D + ++ + F ++ Sbjct: 172 DHDHDSRLSKKDFKDAVL 189 Score = 33.5 bits (75), Expect = 0.054, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 41/110 (37%), Gaps = 9/110 (8%) Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEG--LRVFDKEGN 145 T+ EV ++ + K MD F +L ED + R FDK+ + Sbjct: 42 TKTEVESLIICYKNLLEGLK-MDRNLFRDILHQKF-----NMTEDLLMDRVFRAFDKDSD 95 Query: 146 GTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 + E L+ ++++E + + +G I+ E + + + Sbjct: 96 SYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKT 145 >3H4S-E nrPDB Length = 135 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 34/86 (39%), Gaps = 4/86 (4%) Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLG-ERLTEDE 168 +E LP++ K + +G + + LR LG E +++++ Sbjct: 21 KYEDMLPVMAE--KMDVEEFVSELCKGFSLLADPERHLITAESLRRNSGILGIEGMSKED 78 Query: 169 VEKLMAGQE-DSNGCINYEAFVKHIM 193 + ++ + D +G +N F ++ Sbjct: 79 AQGMVREGDLDGDGALNQTEFCVLMV 104 >3DD4-A nrPDB Length = 229 Score = 37.4 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 14/104 (13%), Positives = 34/104 (32%), Gaps = 16/104 (15%) Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + + + FE F+ L + + E ++D +G + E+ ++ Sbjct: 110 AFDTDHNGAVSFEDFIKGLSILLRG---TVQEKLNWAFNLYDINKDGYITKEEMLDIMKA 166 Query: 160 ------------LGERLTEDEVEKLM-AGQEDSNGCINYEAFVK 190 L E VE ++ +G + + F++ Sbjct: 167 IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIE 210 >1YX7-A nrPDB Length = 83 Score = 37.0 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Query: 132 DFVEGLRVFDKEGNGTVMGAELRHVLATLG--ERLTEDEVEKLMA-----GQEDSNGCIN 184 + + D G+G V EL+ + TL + L++D+V++ A ++S+G I+ Sbjct: 8 ELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKIS 67 Query: 185 YEAFVK 190 E F+ Sbjct: 68 KEEFLN 73 >1S6C-A nrPDB Length = 183 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 14/104 (13%), Positives = 35/104 (33%), Gaps = 16/104 (15%) Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + T + FE F+ L + + +E ++D +G + E+ ++ Sbjct: 64 AFDTTQTGSVKFEDFVTALSILLRG---TVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 120 Query: 160 ------------LGERLTEDEVEKLM-AGQEDSNGCINYEAFVK 190 L E V+ ++ +G + + F++ Sbjct: 121 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLE 164 >1G33-A nrPDB Length = 73 Score = 36.6 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 4/62 (6%) Query: 131 EDFVEGLRVFDKEGNGTVMGAELRHVLATL---GERLTEDEVEKLMAG-QEDSNGCINYE 186 +D + + DK+ +G + EL +L L+ E + LMA +D +G I E Sbjct: 5 DDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVE 64 Query: 187 AF 188 F Sbjct: 65 EF 66 >1S1E-A nrPDB Length = 224 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 14/104 (13%), Positives = 35/104 (33%), Gaps = 16/104 (15%) Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + T + FE F+ L + + +E ++D +G + E+ ++ Sbjct: 97 AFDTTQTGSVKFEDFVTALSILLRG---TVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 153 Query: 160 ------------LGERLTEDEVEKLM-AGQEDSNGCINYEAFVK 190 L E V+ ++ +G + + F++ Sbjct: 154 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLE 197 >2LCP-A nrPDB Length = 190 Score = 35.8 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 42/101 (41%), Gaps = 16/101 (15%) Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 +E ++F F+ L S+ E +++D + +G + E+ ++ + Sbjct: 72 FDENKDGRIEFSEFIQALSVTSRG---TLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAI 128 Query: 161 GE------RLTEDE------VEKLMAGQE-DSNGCINYEAF 188 + L E+E V+++ A + +++G + + F Sbjct: 129 YQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEF 169 Score = 32.0 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 17/106 (16%), Positives = 40/106 (37%), Gaps = 4/106 (3%) Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGT 147 T+ EV + ++ + +D F + + D + FV VFD+ +G Sbjct: 23 TEKEVQQWYKGFIKD-CPSGQLDAAGFQKIYKQFFPFGDPTKFATFV--FNVFDENKDGR 79 Query: 148 VMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 + +E L+ ++++ + D++G I + + Sbjct: 80 IEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIV 125 Score = 26.6 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 31/104 (29%), Gaps = 31/104 (29%) Query: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDF 111 E+ + AF L+D + T+ E+L ++ Q NT + Sbjct: 99 EKLRWAFKLYDLDNDGYI------------------TRNEMLDIVDAIYQMVGNTVELPE 140 Query: 112 ETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRH 155 E P + + DK +G + E + Sbjct: 141 EENTP-------------EKRVDRIFAMMDKNADGKLTLQEFQE 171 >1J7Q-A nrPDB Length = 86 Score = 35.4 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 46 FTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELN 105 PE+ +E + F +FDR + ++ D+L LGQ T+ E ++ + R + + Sbjct: 8 LGPEEKDECMKIFDIFDRNAENIAPVS--DTMDMLTKLGQTYTKRETEAIMKEARGPKGD 65 Query: 106 TKMMDFETFLPMLQHISKNKD 126 K + E +L + + D Sbjct: 66 KKNIGPEEWLTLCSKWVRQDD 86 Score = 30.4 bits (67), Expect = 0.54, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 22/55 (40%) Query: 127 TGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNG 181 ++ ++ +FD+ ++ +L LG+ T+ E E +M G Sbjct: 10 PEEKDECMKIFDIFDRNAENIAPVSDTMDMLTKLGQTYTKRETEAIMKEARGPKG 64 >2E6W-A nrPDB Length = 100 Score = 35.4 bits (80), Expect = 0.018, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 28/74 (37%), Gaps = 13/74 (17%) Query: 130 YEDFVEGLRVFDKEGNGTVMGAELRHVLAT------------LGERLTEDEVEKLMAGQE 177 +E ++D +G + E+ ++ + L E + VE+ + Sbjct: 8 HEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMD 67 Query: 178 -DSNGCINYEAFVK 190 + +G + E F++ Sbjct: 68 RNQDGVVTIEEFLE 81 >4MEW-A nrPDB Length = 356 Score = 34.7 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 41/138 (29%), Gaps = 24/138 (17%) Query: 49 EQIEEF--KEAF-----MLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 Q+ EF E F ++ ++ I ++ A +++ + Sbjct: 178 NQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLA-------RHNDHALSTKMIDRIFS 230 Query: 102 EE-------LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELR 154 + + F+ L +D T R D +G+G + EL Sbjct: 231 GAVTRGRKVQKEGKISYADFVWFL---ISEEDKKTPTSIEYWFRCMDLDGDGALSMFELE 287 Query: 155 HVLATLGERLTEDEVEKL 172 + RL +E L Sbjct: 288 YFYEEQCRRLDSMAIEAL 305 >4I5L-B nrPDB Length = 413 Score = 34.7 bits (78), Expect = 0.025, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 41/138 (29%), Gaps = 24/138 (17%) Query: 49 EQIEEF--KEAF-----MLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 Q+ EF E F ++ ++ I ++ A +++ + Sbjct: 186 NQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLA-------RHNDHALSTKMIDRIFS 238 Query: 102 EE-------LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELR 154 + + F+ L +D T R D +G+G + EL Sbjct: 239 GAVTRGRKVQKEGKISYADFVWFL---ISEEDKKTPTSIEYWFRCMDLDGDGALSMFELE 295 Query: 155 HVLATLGERLTEDEVEKL 172 + RL +E L Sbjct: 296 YFYEEQCRRLDSMAIEAL 313 >4P5W-A nrPDB Length = 411 Score = 34.7 bits (78), Expect = 0.026, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 46/113 (40%), Gaps = 15/113 (13%) Query: 86 NPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGN 145 NP E+L + ++ ++ F+ F+ + F+ ++FDK G Sbjct: 76 NPKTVELLSGV----VDQTKDGLISFQEFVAFESVLCAPDAL-----FMVAFQLFDKAGK 126 Query: 146 GTVMGAELRHVL--ATLGERLT---EDEVEKLMAGQEDSNGCINYEAFVKHIM 193 G V +++ V T+ + + + E +L G+E + Y F + ++ Sbjct: 127 GEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKR-HLTYAEFTQFLL 178 Score = 31.2 bits (69), Expect = 0.33, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 35/111 (31%), Gaps = 16/111 (14%) Query: 54 FKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEV----LRVLGKPRQEELNTKMM 109 F AF LFD+ K E +T+ V GQ + + + + + Sbjct: 114 FMVAFQLFDKAGKGE--VTFEDVKQVF---GQTTIHQHIPFNWDSEFVQLHFGKERKRHL 168 Query: 110 DFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 + F L I E + D G V + R ++ T+ Sbjct: 169 TYAEFTQFLLEI-------QLEHAKQAFVQRDNARTGRVTAIDFRDIMVTI 212 >1NYA-A nrPDB Length = 176 Score = 34.3 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 21/158 (13%), Positives = 55/158 (34%), Gaps = 19/158 (12%) Query: 52 EEFKEAFMLFDRTPKC--EMKITYGQCGDVLRALGQNPTQAEVLRVLGKP---------R 100 + K+ F +D E + + A G++ AEV + Sbjct: 7 DRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKE 66 Query: 101 QEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGL-----RVFDKEGNGTVMGAELRH 155 + + E F+ + +++ + ++ + + + DK +G + E Sbjct: 67 AGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAA 126 Query: 156 VLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 L LG +++ E + + + NG ++ + + + Sbjct: 127 WLTALG--MSKAEAAEAFNQVDTNGNGELSLDELLTAV 162 >2Q4U-A nrPDB Length = 272 Score = 34.3 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 20/159 (12%), Positives = 63/159 (39%), Gaps = 40/159 (25%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 K + T E++++ K++F + + ++ + +++ P + Sbjct: 47 KDKITDERVQQIKKSF-MSAYDATFDGRLQIEELANMI-----LPQE------------- 87 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL-- 160 E FL + + +F++ R +D + +G + AEL++ L L Sbjct: 88 ---------ENFLLIFRR---EAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLFL 135 Query: 161 --GERLTEDEVEK----LMAGQE-DSNGCINYEAFVKHI 192 +++ +++++ +M + + +G ++ + + Sbjct: 136 QHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARIL 174 >1QS1-A nrPDB Length = 462 Score = 34.3 bits (77), Expect = 0.036, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAE---VLRVLGKPRQEEL 104 ++I++ KE +FD+T ITY +G N + E + +E+ Sbjct: 120 EDEIKDLKEIDKMFDKTNLSNSIITYKNVEPT--TIGFNKSLTEGNTINSDAMAQFKEQF 177 Query: 105 NTKMMDFETFL 115 + + F+++L Sbjct: 178 LDRDIKFDSYL 188 >3AKA-A nrPDB Length = 166 Score = 34.3 bits (77), Expect = 0.037, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 44/152 (28%), Gaps = 26/152 (17%) Query: 58 FMLFDRTPKCEMKITYGQCGDVLRAL----GQNPTQAEVLRVLGKPRQ---------EEL 104 F FD+ I +AL G + G + Sbjct: 10 FTTFDQD--GNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIADRD 67 Query: 105 NTKMMDFETFLPMLQHISKNKDTGTYEDFVE-----GLRVFDKEGNGTVMGAELRHVLAT 159 + + E F+ ++K + + L V D +G+G V A+ L Sbjct: 68 GDQRITREEFVTGAVKRLRDK-PDRFAEIARPFLHAALGVADTDGDGAVTVADTARALTA 126 Query: 160 LGERLTEDEV--EKLMAGQEDSNGCINYEAFV 189 G +++ + A D +G + V Sbjct: 127 FG---VPEDLARQAAAALDTDGDGKVGETEIV 155 >2HPS-A nrPDB Length = 186 Score = 34.3 bits (77), Expect = 0.038, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Query: 121 ISKNKDTGTYEDFVEGLRVFD---KEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 + K K ++ L ++D + +G V E + L +G LT+D+ + Sbjct: 89 LLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLD 148 Query: 178 -DSNGCINYEAFVKHI 192 + NG I+ + F+ + Sbjct: 149 FNKNGQISRDEFLVTV 164 >2D8N-A nrPDB Length = 207 Score = 34.3 bits (77), Expect = 0.039, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 37/81 (45%), Gaps = 6/81 (7%) Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + +DF+ ++ L + K T + ++D +GNGT+ E+ ++ Sbjct: 79 SFDSNLDGTLDFKEYVIALHMTTAGK---TNQKLEWAFSLYDVDGNGTISKNEVLEIVMA 135 Query: 160 LGERLTEDEVEKLMAGQEDSN 180 + + +T ++V+ L +D N Sbjct: 136 IFKMITPEDVKLL---PDDEN 153 Score = 32.7 bits (73), Expect = 0.10, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 34/90 (37%), Gaps = 3/90 (3%) Query: 106 TKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLT 165 T + + F + + D Y V R FD +GT+ E L T Sbjct: 48 TGRITQQQFQSIYAKFFPDTDPKAYAQHV--FRSFDSNLDGTLDFKEYVIALHMTTAGKT 105 Query: 166 EDEVEKLMAGQE-DSNGCINYEAFVKHIMS 194 ++E + + D NG I+ ++ +M+ Sbjct: 106 NQKLEWAFSLYDVDGNGTISKNEVLEIVMA 135 >1QS2-A nrPDB Length = 401 Score = 33.5 bits (75), Expect = 0.054, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 48 PEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAE---VLRVLGKPRQEEL 104 ++I++ KE +FD+T ITY +G N + E + +E+ Sbjct: 59 EDEIKDLKEIDKMFDKTNLSNSIITYKNVEPT--TIGFNKSLTEGNTINSDAMAQFKEQF 116 Query: 105 NTKMMDFETFL 115 + + F+++L Sbjct: 117 LDRDIKFDSYL 127 >2I94-A nrPDB Length = 202 Score = 33.1 bits (74), Expect = 0.070, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 + + +DF+ ++ L S K T + ++D +GNGT+ E+ ++ Sbjct: 72 SFDANSDGTLDFKEYVIALHMTSAGK---TNQKLEWAFSLYDVDGNGTISKNEVLEIVTA 128 Query: 160 LGERLTEDEVEKL 172 + + ++ ++ + L Sbjct: 129 IFKMISPEDTKHL 141 >4NQG-A nrPDB Length = 197 Score = 33.1 bits (74), Expect = 0.073, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVK 190 + DK+GNG+V E G + + + E A + D +G ++ + + Sbjct: 120 FDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMTR 174 >2MBX-A nrPDB Length = 109 Score = 33.1 bits (74), Expect = 0.076, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 9/95 (9%) Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL--- 160 D + F + +K + D + + D++ + V EL+ L Sbjct: 20 KAEGSFDHKAFFTKVGLAAK-----SPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAG 74 Query: 161 GERLTEDEVEKLMAG-QEDSNGCINYEAFVKHIMS 194 L++ E + + D +G I + F I + Sbjct: 75 ARALSDAETKVFLKAGDSDGDGKIGVDEFGAMIKA 109 >5XOP-A nrPDB Length = 66 Score = 33.1 bits (74), Expect = 0.077, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 28/57 (49%), Gaps = 3/57 (5%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM--AGQEDSNGCINYEAFVKH 191 + D G+G V E++ + + +++ +L+ + +D +G I++E F K Sbjct: 6 FKEIDVNGDGAVSYEEVK-AFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 Score = 28.1 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 18/53 (33%), Gaps = 3/53 (5%) Query: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELR 154 + + +E + SK + + + DK+G+G + E Sbjct: 10 DVNGDGAVSYEEVKAFV---SKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFA 59 >3LCP-C nrPDB Length = 93 Score = 33.1 bits (74), Expect = 0.080, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 40/89 (44%), Gaps = 14/89 (15%) Query: 118 LQHISKNKDTGTYEDF-VEGLRVFDKEGNGTVMGAELRHVLA--------TLGERLTEDE 168 + I+K + + ++ + ++ D +GN + G EL + ++EDE Sbjct: 4 MGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDE 63 Query: 169 VEKLMAG-----QEDSNGCINYEAFVKHI 192 + ++ G ++++G I+Y F K + Sbjct: 64 LINIIDGVLRDDDKNNDGYIDYAEFAKSL 92 >1IJ5-A nrPDB Length = 323 Score = 32.7 bits (73), Expect = 0.098, Method: Composition-based stats. Identities = 21/149 (14%), Positives = 42/149 (28%), Gaps = 17/149 (11%) Query: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 K + E ++ F K ++ VL + + ++ + Sbjct: 113 KPMLSEEDTNILRQLF--LSSAVSGSGKFSFQDLKQVLAKYADTIPEGPLKKLFVMVEND 170 Query: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 162 + +I+ V R D NGT+ E R LG Sbjct: 171 TKGR-----------MSYITLVAVANDLAALVADFRKIDTNSNGTLSRKEFREHFVRLG- 218 Query: 163 RLTEDEVEKLM--AGQEDSNGCINYEAFV 189 + V+ + ED + + + +V Sbjct: 219 -FDKKSVQDALFRYADEDESDDVGFSEYV 246 >4I5K-A nrPDB Length = 285 Score = 32.4 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 23/61 (37%), Gaps = 3/61 (4%) Query: 104 LNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 M + F+ L ++ + E + R D +G+G + EL + ER Sbjct: 166 QKEGRMSYADFVWFLISEEDKRNPTSIEYW---FRCMDVDGDGVLSMYELEYFYEEQCER 222 Query: 164 L 164 + Sbjct: 223 M 223 >5LN3-Z nrPDB Length = 908 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 50/151 (33%), Gaps = 22/151 (14%) Query: 7 EPKKDDAKAAPKAAPAPAPPPEPERP--KEVEFDASKIKIE-FTPEQIEEFKEAFMLFDR 63 E +D A P+ +PA AP E+P KE K K + + E + E ML +R Sbjct: 3 EGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLVER 62 Query: 64 TPKCEMKITYGQCGDVLRALG---------------QNPTQAEVLRVLGKPRQEELNTKM 108 + + + ++ R + P ++ + E Sbjct: 63 LGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKRFA 122 Query: 109 MDFETFLPML----QHISKNKDTGTYEDFVE 135 D + L M + K + G+ E+ Sbjct: 123 ADIISVLAMTMSGERECLKYRLVGSQEELAS 153 >1ZFS-A nrPDB Length = 93 Score = 32.0 bits (71), Expect = 0.18, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 31/60 (51%), Gaps = 7/60 (11%) Query: 142 KEGNGT-VMGAELRHVLAT-----LGERLTEDEVEKLMAG-QEDSNGCINYEAFVKHIMS 194 KEG+ + EL+ +L T L + D V+K+M E+ +G ++++ FV + + Sbjct: 21 KEGDKYKLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAA 80 >4DDO-A nrPDB Length = 451 Score = 31.6 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 40/125 (32%), Gaps = 26/125 (20%) Query: 72 TYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYE 131 + GD +R + G+ F+ ++ TG E Sbjct: 196 SVQAIGDAMRMI-----------RTGEADVVLAGGAEAAFDKVSLGGFAAARALSTGFSE 244 Query: 132 DFVEGLRVFDKEGNGTVM--------GAELRHVLATLGERL-------TEDEVEKLMAGQ 176 + V R FD++ +G VM L H LA + T + + AG Sbjct: 245 EPVRASRPFDRDRDGFVMGEGAAMVVVESLDHALARGARPIAEIIGYGTTADAYHMTAGP 304 Query: 177 EDSNG 181 +D +G Sbjct: 305 DDGSG 309 >4YGB-B nrPDB Length = 104 Score = 31.2 bits (69), Expect = 0.26, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 34/83 (40%), Gaps = 13/83 (15%) Query: 123 KNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA--------TLGERLTEDEVEKLMA 174 + E + ++ D +GN + G EL + ++EDE+ ++ Sbjct: 21 HMLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIID 80 Query: 175 G-----QEDSNGCINYEAFVKHI 192 G ++++G I+Y F K + Sbjct: 81 GVLRDDDKNNDGYIDYAEFAKSL 103 >2VRG-A nrPDB Length = 124 Score = 31.2 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 34/82 (41%), Gaps = 13/82 (15%) Query: 124 NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA--------TLGERLTEDEVEKLMAG 175 + E + ++ D +GN + G EL + ++EDE+ ++ G Sbjct: 42 EAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 101 Query: 176 -----QEDSNGCINYEAFVKHI 192 ++++G I+Y F K + Sbjct: 102 VLRDDDKNNDGYIDYAEFAKSL 123 >2I18-A nrPDB Length = 64 Score = 31.2 bits (69), Expect = 0.32, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 26/56 (46%), Gaps = 5/56 (8%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLG-ERLTEDEVEKLMAGQEDSNGCINYEAFVKH 191 ++ D +G+G + E+ G E++ E++M + +G I E F++ Sbjct: 11 YKLMDVDGDGKLTKEEVTSFFKKHGIEKVA----EQVMKADANGDGYITLEEFLEF 62 >3A4U-B nrPDB Length = 143 Score = 30.8 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 34/82 (41%), Gaps = 13/82 (15%) Query: 124 NKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA--------TLGERLTEDEVEKLMAG 175 + E + ++ D +GN + G EL + ++EDE+ ++ G Sbjct: 61 EAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDG 120 Query: 176 -----QEDSNGCINYEAFVKHI 192 ++++G I+Y F K + Sbjct: 121 VLRDDDKNNDGYIDYAEFAKSL 142 >2JMM-A nrPDB Length = 156 Score = 30.8 bits (68), Expect = 0.41, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 15/70 (21%) Query: 83 LGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDK 142 LG+ P +A+ +++ K +L T +D + + DK Sbjct: 47 LGRMPRKAQGVQLTAKLGYPKLGTDDLD------IYTRLGGMVWRADTS---------DK 91 Query: 143 EGNGTVMGAE 152 +GNG + AE Sbjct: 92 DGNGYISAAE 101 >6R7Z-A nrPDB Length = 667 Score = 30.8 bits (68), Expect = 0.41, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 45/134 (33%), Gaps = 11/134 (8%) Query: 42 IKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGD--VLRALGQNPTQAEVLRVLGKP 99 + IE + EE KE K + G + R L N + E L Sbjct: 19 VVIELAQDVKEETKE-------WLKNRIIAKKKDGGAQLLFRPL-LNKYEQETLENQNLY 70 Query: 100 RQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLAT 159 +M+ + +++ + N + + FD + + AE + ++ Sbjct: 71 LVGASKIRMLLGAEAVGLVKECNDNTMRAFTYRTRQNFKGFDDNNDDFLTMAECQFIIKH 130 Query: 160 LGERLTEDEVEKLM 173 E L + EK++ Sbjct: 131 ELENLRAKD-EKMI 143 >4TX3-A nrPDB Length = 404 Score = 30.4 bits (67), Expect = 0.44, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 25/45 (55%), Gaps = 10/45 (22%) Query: 144 GNGTVMGAELRHVLATLGERLTEDE-----VEKLMAGQEDSNGCI 183 G+G + ++A G+ +T++E V+ ++AG ++ +G I Sbjct: 212 GDGFI-----GSIVAEHGDTITDEELRGVCVQLMLAGDDNVSGMI 251 >6FSH-A nrPDB Length = 398 Score = 30.4 bits (67), Expect = 0.45, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 25/45 (55%), Gaps = 10/45 (22%) Query: 144 GNGTVMGAELRHVLATLGERLTEDE-----VEKLMAGQEDSNGCI 183 G+G + ++A G+ +T++E V+ ++AG ++ +G I Sbjct: 206 GDGFI-----GSIVAEHGDTITDEELRGVCVQLMLAGDDNVSGMI 245 >2L0P-A nrPDB Length = 94 Score = 29.7 bits (65), Expect = 0.81, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 31/60 (51%), Gaps = 7/60 (11%) Query: 142 KEGNGT-VMGAELRHVLAT-----LGERLTEDEVEKLMAG-QEDSNGCINYEAFVKHIMS 194 KEG+ + EL+ +L T L + D V+K+M E+ +G ++++ +V + + Sbjct: 22 KEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAA 81 >5GAH-J nrPDB Length = 142 Score = 29.7 bits (65), Expect = 0.84, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 17/36 (47%) Query: 142 KEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 K+ G + A+L+ + T +T ++E + E Sbjct: 95 KDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIE 130 >2MA2-A nrPDB Length = 81 Score = 29.7 bits (65), Expect = 0.96, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 27/65 (41%), Gaps = 18/65 (27%) Query: 137 LRVFDKEGNGTVMGAELRHV------LATLGERLTEDEVEKLMAGQEDSNGCINYEAFVK 190 R FD +G+G + E + + L+ G+ ++ +GCI+ E V Sbjct: 19 FRNFDVDGDGHISQEEFQIIRGNFPYLSAFGD------------LDQNQDGCISREEMVS 66 Query: 191 HIMSS 195 + + S Sbjct: 67 YFLRS 71 >6AGI-A nrPDB Length = 382 Score = 29.3 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 38/103 (36%), Gaps = 21/103 (20%) Query: 88 TQAEVLRVLGKPRQEELNTKM----------MDFETFLPMLQHISKNKDTGTYEDFVEGL 137 ++ E+ ++L + + + + +L +L ++K + F Sbjct: 57 SKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKP-----HAGFRIAF 111 Query: 138 RVFDKEGNGTVMGAE---LRHVLATLGERLT---EDEVEKLMA 174 +FD +GN V E L+ + E+ ++E ++ Sbjct: 112 NMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLR 154 >5A1W-H nrPDB Length = 511 Score = 29.3 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 17 PKAAPAPAPPPEPERPKEVEFDASKI 42 PK APAPA P P + ++ ++ Sbjct: 210 PKVAPAPARPSGPSKALKLGAKGKEV 235 >2M7M-A nrPDB Length = 66 Score = 29.3 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 25/57 (43%), Gaps = 3/57 (5%) Query: 137 LRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLM--AGQEDSNGCINYEAFVKH 191 + D G+G V E++ + + +++ +L+ + D NG I+ F K Sbjct: 6 FKEIDVNGDGAVSYEEVK-AFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 >3KRB-A nrPDB Length = 334 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 22/64 (34%) Query: 59 MLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPML 118 LF + + + D RA+ Q + V + L ++++ P++ Sbjct: 137 DLFPKDAEGRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLV 196 Query: 119 QHIS 122 I Sbjct: 197 NQIE 200 >6MI5-X nrPDB Length = 117 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 28/57 (49%), Gaps = 10/57 (17%) Query: 136 GLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHI 192 D + +GT+ EL+ R++E +++KL D++G ++ + ++ + Sbjct: 32 AFDKLDPDKDGTLDAKELK-------GRVSEADLKKL---DPDNDGTLDKKEYLAAV 78 >1SP9-A nrPDB Length = 445 Score = 28.5 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 37/84 (44%), Gaps = 12/84 (14%) Query: 23 PAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRA 82 P+PPP + + ++ + +QI+E +E +L DR + + + Sbjct: 336 PSPPPTYYQNLK-----KRVGDVLSDDQIKECEELGILVDRDDQGTL------LQIFTKP 384 Query: 83 LGQNPT-QAEVLRVLGKPRQEELN 105 LG PT E+++ +G ++E Sbjct: 385 LGDRPTIFIEIIQRVGCMMKDEEG 408 >2WCE-A nrPDB Length = 95 Score = 28.5 bits (62), Expect = 2.0, Method: Composition-based stats. Identities = 7/57 (12%), Positives = 26/57 (45%), Gaps = 7/57 (12%) Query: 140 FDKEGNGTVM---GAELRHVLATLGERLTEDEVEKLMAGQE-DSNGCINYEAFVKHI 192 FD G + EL + + + ++ ++++ G + + + ++++ F+ + Sbjct: 28 FDTLSKGELKQLLTKELANTIKNIKDKAV---IDEIFQGLDANQDEQVDFQEFISMV 81 >3MC8-A nrPDB Length = 316 Score = 28.5 bits (62), Expect = 2.1, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 20/48 (41%), Gaps = 4/48 (8%) Query: 2 APKKPEPKKDDAKAAPKAAPAPAPPPEP-ERPKEVEFDASKIKIEFTP 48 AP++P P+ + AP PAP P P P F+ E T Sbjct: 15 APEQPAPQPE---VAPPTTEQPAPAPAPGTTPGTENFNTPNATPETTE 59 >6BY1-CI nrPDB Length = 72 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 17/36 (47%) Query: 142 KEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQE 177 K+ G + A+L+ + T +T ++E + E Sbjct: 25 KDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIE 60 >2HSZ-A nrPDB Length = 243 Score = 28.1 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 23/60 (38%) Query: 24 APPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRAL 83 + + V++ + + E T ++ + FK F + C + Y + L AL Sbjct: 67 GNGADVLSQRAVDWACKQAEKELTEDEFKYFKRQFGFYYGENLCNISRLYPNVKETLEAL 126 >4UPH-A nrPDB Length = 547 Score = 27.7 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 6 PEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDAS 40 P+ +K A P ++ P P P +E+ S Sbjct: 7 PQFEKGAETAVPNSSSVPGDPSSMPNPTSIEWRPS 41 >4L9M-A nrPDB Length = 559 Score = 27.7 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 4/23 (17%), Positives = 11/23 (47%) Query: 137 LRVFDKEGNGTVMGAELRHVLAT 159 + +D + +G + E + A+ Sbjct: 431 FKNYDHDQDGYISQEEFEKIAAS 453 >6IIE-A nrPDB Length = 93 Score = 27.7 bits (60), Expect = 3.6, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 36/74 (48%), Gaps = 11/74 (14%) Query: 128 GTYEDFVE-GLRVFDKEGNGTVMGAELRHV---LATLGERLTEDE------VEKLMAGQE 177 G ED +E +++D + NG + +E+ + + + E L D ++++M + Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEID 64 Query: 178 -DSNGCINYEAFVK 190 D +G ++ +V+ Sbjct: 65 YDGSGSVSQAEWVR 78 >4Z8X-A nrPDB Length = 497 Score = 27.7 bits (60), Expect = 3.6, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 29/65 (44%), Gaps = 1/65 (1%) Query: 89 QAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTV 148 EV R++ + E+ + +++ L + K+T T E+FVE +++ E Sbjct: 411 DEEVRRIITEQ-YEKAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGIELKDKC 469 Query: 149 MGAEL 153 EL Sbjct: 470 KKEEL 474 >3FVB-A nrPDB Length = 182 Score = 27.3 bits (59), Expect = 4.1, Method: Composition-based stats. Identities = 15/102 (14%), Positives = 30/102 (29%), Gaps = 2/102 (1%) Query: 36 EFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRV 95 ++ +++ + E IEE A L DR E + +GQN + + Sbjct: 55 DWGYTRLAKKEREESIEEMHHADKLIDRIIFLEGFPNLQTVSPL--RIGQNVKEVLEADL 112 Query: 96 LGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGL 137 G+ + + L + E+ Sbjct: 113 KGEYDARASYKESREICDKLGDYVSKQLFDELLADEEGHIDF 154 >5W2O-A nrPDB Length = 439 Score = 27.3 bits (59), Expect = 4.2, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 18/51 (35%) Query: 113 TFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGER 163 LP+ + ++ R FDK+ +G V G +L E Sbjct: 226 EALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEH 276 >4NSC-A nrPDB Length = 401 Score = 27.3 bits (59), Expect = 4.5, Method: Composition-based stats. Identities = 7/21 (33%), Positives = 10/21 (47%) Query: 136 GLRVFDKEGNGTVMGAELRHV 156 ++FD G+G V E V Sbjct: 151 AFKMFDLNGDGEVDMEEFEQV 171 Score = 26.6 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 41/127 (32%), Gaps = 29/127 (22%) Query: 61 FDRTPKCEMKITYGQCGDVLRALGQNPTQA--EVLRVLGKPRQEELNTKMMDFETFLPML 118 F+R + +IT Q G +L A ++ + R L K +E + E F L Sbjct: 237 FERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFL 296 Query: 119 QHISKNKDTGTYEDFVEG---------------------------LRVFDKEGNGTVMGA 151 ++I+ ++ +FD +GNG + Sbjct: 297 KNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNK 356 Query: 152 ELRHVLA 158 E ++ Sbjct: 357 EFVSIMK 363 >1QLS-A nrPDB Length = 99 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 30/58 (51%), Gaps = 7/58 (12%) Query: 142 KEGNGT-VMGAELRHVLATLGERLTEDE-----VEKLMAGQE-DSNGCINYEAFVKHI 192 ++GN T + E + T T+++ ++++M + DS+G ++++ F+ I Sbjct: 25 RDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDLDSDGQLDFQEFLNLI 82 >2NCO-A nrPDB Length = 102 Score = 27.3 bits (59), Expect = 4.8, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 33/70 (47%), Gaps = 8/70 (11%) Query: 134 VEGLRVFDKEGNGTVMGAELRHVLA-TLGE------RLTEDEVEKLMA-GQEDSNGCINY 185 + +DK+G+G + E+ +L T E T+++V+ + +S+G ++ Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVSL 77 Query: 186 EAFVKHIMSS 195 E + I+ S Sbjct: 78 EEYEDLIIKS 87 >2DI4-A nrPDB Length = 238 Score = 27.0 bits (58), Expect = 4.8, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 89 QAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTV 148 EV R++ + E+ + +++ L + K+T T E+FVE +++ E Sbjct: 152 DEEVKRIITEQ-YEKAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGIELKDKC 210 Query: 149 MGAELRHVLATLGER--LTEDEVEK 171 EL E L +EV++ Sbjct: 211 KKEELFDKDRKSEENKELKSEEVKE 235 >1CM8-A nrPDB Length = 367 Score = 27.0 bits (58), Expect = 5.3, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 47 TPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVL--RALGQNPTQA 90 Q++++ ++F DRT ++TY + R LG ++ Sbjct: 319 DEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGARVSKE 364 >1I7F-A nrPDB Length = 292 Score = 27.0 bits (58), Expect = 5.9, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 45/127 (35%), Gaps = 14/127 (11%) Query: 59 MLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPML 118 LF RT + K G G +L+ + Q + L T+ + E L + Sbjct: 153 RLFIRTGDVDGKPAAG--GMLLQVMPAQNAQQDDFDHLATL------TETIKTEELLTLP 204 Query: 119 QHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQED 178 + + +E+ V D E T L TL ++EV+ ++A + Sbjct: 205 ANEVLWRLY--HEEEVTVYDPQDVEFKCTCSRERSADALKTL----PDEEVDSILAEDGE 258 Query: 179 SNGCINY 185 + +Y Sbjct: 259 IDMHCDY 265 >1CB1-A nrPDB Length = 78 Score = 27.0 bits (58), Expect = 6.0, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 26/67 (38%), Gaps = 1/67 (1%) Query: 88 TQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGT 147 + AE+ + K +E + + E ++Q + G + + DK G+G Sbjct: 5 SPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKG-PRTLDDLFQELDKNGDGE 63 Query: 148 VMGAELR 154 V E + Sbjct: 64 VSFEEFQ 70 >1C07-A nrPDB Length = 95 Score = 27.0 bits (58), Expect = 6.2, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%), Gaps = 3/49 (6%) Query: 141 DKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSN-GCINYEAF 188 DK+ +G V G E+R + G L + + + + + G ++ + F Sbjct: 20 DKDMDGFVSGLEVREIFLKTG--LPSTLLAHIWSLCDTKDCGKLSKDQF 66 >3CS1-A nrPDB Length = 219 Score = 26.6 bits (57), Expect = 7.9, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 21/64 (32%), Gaps = 4/64 (6%) Query: 91 EVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMG 150 E+ + + + ++D E F + ED + DK G G+V Sbjct: 131 ELTVMFDEI--DASGNMLVDEEEFKRAV--PKLEAWGAKVEDPAALFKELDKNGTGSVTF 186 Query: 151 AELR 154 E Sbjct: 187 DEFA 190 >1IRX-A nrPDB Length = 523 Score = 26.2 bits (56), Expect = 8.8, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 21/51 (41%) Query: 90 AEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVF 140 +V + + + N + E F +L ++K + + E F R+F Sbjct: 444 EDVREAMNEVAEWLENHEEFSVEEFNNILFEVAKRRGISSREWFSTLYRLF 494 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.133 0.353 Lambda K H 0.267 0.0404 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,708,979 Number of Sequences: 36641 Number of extensions: 303594 Number of successful extensions: 2885 Number of sequences better than 10.0: 314 Number of HSP's better than 10.0 without gapping: 411 Number of HSP's successfully gapped in prelim test: 79 Number of HSP's that attempted gapping in prelim test: 1214 Number of HSP's gapped (non-prelim): 843 length of query: 195 length of database: 10,336,785 effective HSP length: 92 effective length of query: 103 effective length of database: 6,965,813 effective search space: 717478739 effective search space used: 717478739 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.5 bits) S2: 56 (26.2 bits)