BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08417 (488 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1YFM-A nrPDB 1011 0.0 5UPP-A nrPDB 637 0.0 4HGV-A nrPDB 602 e-172 3GTD-A nrPDB 574 e-164 6N1M-A nrPDB 573 e-164 3TV2-A nrPDB 558 e-159 1FUP-A nrPDB 542 e-154 1VDK-A nrPDB 533 e-152 3RD8-A nrPDB 424 e-119 3QBP-A nrPDB 417 e-117 4ADL-A nrPDB 412 e-115 3R6Q-A nrPDB 402 e-112 3RRP-A nrPDB 400 e-112 3OCE-A nrPDB 335 3e-92 1JSW-A nrPDB 311 3e-85 5EYT-A nrPDB 64 2e-10 1RE5-A nrPDB 61 1e-09 2PFM-A nrPDB 59 3e-09 1TJ7-A nrPDB 58 1e-08 4MX2-A nrPDB 57 2e-08 1F1O-A nrPDB 57 2e-08 2E9F-A nrPDB 55 1e-07 3BHG-A nrPDB 53 2e-07 2X75-A nrPDB 52 4e-07 1C3C-A nrPDB 52 6e-07 1Q5N-A nrPDB 51 1e-06 4EEI-A nrPDB 51 1e-06 4EFC-A nrPDB 49 6e-06 3C8T-A nrPDB 48 9e-06 5E3V-A nrPDB 47 2e-05 2J91-A nrPDB 47 2e-05 4NSL-A nrPDB 47 2e-05 1I0A-A nrPDB 45 7e-05 2PTS-A nrPDB 45 8e-05 5V4L-A nrPDB 44 1e-04 1TJU-A nrPDB 44 1e-04 5XNZ-A nrPDB 44 2e-04 2QGA-B nrPDB 43 3e-04 1YIS-A nrPDB 40 0.002 1DOF-A nrPDB 39 0.005 5VKW-A nrPDB 36 0.039 2FEL-A nrPDB 36 0.041 6IG5-A nrPDB 35 0.076 1H2B-A nrPDB 32 0.73 6GZH-B nrPDB 32 0.75 3MIA-B nrPDB 32 0.89 2PK2-A nrPDB 31 1.1 4UEJ-A nrPDB 31 1.5 5TUJ-C nrPDB 30 1.8 1A6R-A nrPDB 30 1.8 6G3D-A nrPDB 30 2.3 1AOS-A nrPDB 30 3.1 5L43-A nrPDB 30 3.1 1B65-A nrPDB 29 4.4 4JBT-A nrPDB 29 5.7 >1YFM-A nrPDB Length = 488 Score = 1011 bits (2613), Expect = 0.0, Method: Compositional matrix adjust. Identities = 487/488 (99%), Positives = 488/488 (100%) Query: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG Sbjct: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60 Query: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF Sbjct: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120 Query: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ Sbjct: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180 Query: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV Sbjct: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240 Query: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIV 300 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPN+FEALAAHDAIV Sbjct: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNRFEALAAHDAIV 300 Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ Sbjct: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360 Query: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE Sbjct: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420 Query: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV Sbjct: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480 Query: 481 PEHMLGPK 488 PEHMLGPK Sbjct: 481 PEHMLGPK 488 >5UPP-A nrPDB Length = 466 Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/464 (67%), Positives = 376/464 (81%), Gaps = 2/464 (0%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85 +SFR E D FGE+ VP DKY+GAQT RS NFKIGG ERMP P++ AFG+LK++AA VN Sbjct: 4 NSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVN 63 Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145 + G LDPKI+ AI +AADEVA GKL+DHFPLVV+QTGSGTQ+NMN NEVISNRAIE+LG Sbjct: 64 QDYG-LDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLG 122 Query: 146 GKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204 G++GSK VHPN+H N+SQSSNDTFPT MHIAA++++ L+P L L +AL+AKSKEF Sbjct: 123 GELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFA 182 Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264 I+KIGRTH QDA PLTLGQEFSGYVQQV+ + R+ ++ + LA GGTAVGTGLNT+ Sbjct: 183 QIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTR 242 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 GF K+A +++ TGL F TAPNKFEALAAHDA+VE SGA+NT ACSL KIA DIR+LG Sbjct: 243 IGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLG 302 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384 SGPR G EL+LPENEPGSSIMPGKVNPTQ EA+T V QVMGN+ A+T GS G FELN Sbjct: 303 SGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELN 362 Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444 VFKP+MI N+L+S RL+ DA+ SF +CV GI+AN RI++L+ +SLMLVTALNP IGYD Sbjct: 363 VFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYD 422 Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488 A+K+AK AHK G TLKE+A+ELG LT ++FDEWV P+ MLGPK Sbjct: 423 KAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK 466 >4HGV-A nrPDB Length = 495 Score = 602 bits (1553), Expect = e-172, Method: Compositional matrix adjust. Identities = 299/463 (64%), Positives = 358/463 (77%), Gaps = 3/463 (0%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85 +S RTETD FG I V +D+YWGAQ QRS NFKIG E+ PL +V A G++K++AA N Sbjct: 34 TSTRTETDTFGPIEVASDRYWGAQAQRSLGNFKIG--WEKQPLAIVRALGIVKQAAARAN 91 Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145 +LG LDP I AI +AA EV GKLD+HFPLVV+QTGSGTQSNMNANEV+SNRAIE+LG Sbjct: 92 MALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLG 151 Query: 146 GKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204 G +GSK+ VHPN+H N SQSSNDT+PT MHIA + ++ ++L+P L +L ALE K K FD Sbjct: 152 GVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFD 211 Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264 HI+KIGRTH QDATPLTLGQEFSGY QV + I+R+ +L L LAQGGTAVGTGLN Sbjct: 212 HIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAP 271 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 GF K+AE+I+ TG+ F +APNKFEALAAHD++V GA+N A +LFKIA DIR+LG Sbjct: 272 VGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLG 331 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384 SGPR G EL LPENEPGSSIMPGKVNPTQ EALTQVCVQV GN+AA+TFAGSQG FELN Sbjct: 332 SGPRSGLGELSLPENEPGSSIMPGKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELN 391 Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444 V+ P+M N L S++L+ DAA SF +CV GI+A E I L +SLMLVTAL PKIGYD Sbjct: 392 VYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYD 451 Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 A+K+AK AHK G TL+E A+ G +T++EFD V PE M+GP Sbjct: 452 NAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGP 494 >3GTD-A nrPDB Length = 482 Score = 574 bits (1480), Expect = e-164, Method: Compositional matrix adjust. Identities = 281/460 (61%), Positives = 352/460 (76%), Gaps = 3/460 (0%) Query: 27 SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNE 86 ++R E+D+FGEI + YWGAQTQRS NFKI ++++MP L+ A +LKK AA VN Sbjct: 24 NYRIESDSFGEIQIEEKFYWGAQTQRSLNNFKI--SKQKMPKILIRALAILKKCAAQVNY 81 Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146 G L+ KI+ +I +A D + +G+ +D+FPLVV+QTGSGTQ+NMN NEVI++ A E L G Sbjct: 82 EFGDLEYKIATSIDKAIDRILAGEFEDNFPLVVWQTGSGTQTNMNMNEVIASIANEELTG 141 Query: 147 KIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205 K G K VHPN+H N+ QSSND+FPT MHIA L + +LIP L NL L+ KSK++D Sbjct: 142 KKGGKFPVHPNDHVNKGQSSNDSFPTAMHIATVLATKQQLIPALNNLLTYLQDKSKDWDK 201 Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKP 265 I+KIGRTHLQDATPLTL QEFSGY+ Q+E ++R+ +LK + LAQGGTAVGTG+N+K Sbjct: 202 IIKIGRTHLQDATPLTLKQEFSGYITQIEYALERIEDALKKVYLLAQGGTAVGTGINSKI 261 Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325 GFD+K A+++++ T F+TAPNKFE+LAAHDA+VE SG LNT+A SL KIA DIR LGS Sbjct: 262 GFDIKFAQKVAEFTQQPFKTAPNKFESLAAHDALVEFSGTLNTIAVSLMKIANDIRLLGS 321 Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385 GPRCG EL LPENEPGSSIMPGKVNPTQ EALT VC QVMGN+ +T AGS G ELNV Sbjct: 322 GPRCGLGELHLPENEPGSSIMPGKVNPTQVEALTMVCTQVMGNHVTVTIAGSNGHLELNV 381 Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445 FKPV+I N+L SI L++D+ SF HCV+G++ N RI+ L KSLMLVT LNP IGYD Sbjct: 382 FKPVIIYNILQSIELLSDSVNSFVTHCVKGLEPNIARINTLRDKSLMLVTVLNPHIGYDN 441 Query: 446 ASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485 A+K+AK AHK GITLKE+A +L L+E+EFD+ VVPE M+ Sbjct: 442 AAKIAKEAHKYGITLKEAAKKLNFLSEEEFDKIVVPEKMI 481 >6N1M-A nrPDB Length = 472 Score = 573 bits (1476), Expect = e-164, Method: Compositional matrix adjust. Identities = 280/461 (60%), Positives = 349/461 (75%), Gaps = 3/461 (0%) Query: 29 RTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESL 88 R ETD+ GEI VP+DKYWGAQT+RS +F IG ++ MP + HAFG+LKK+AA+ N L Sbjct: 13 RVETDSMGEIEVPSDKYWGAQTERSLHHFNIG--KDIMPREVTHAFGILKKAAALTNLEL 70 Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148 G L + I QAA+EV+ G LD+HFPL V+QTGSGTQSNMNANEVISNRAIE+ GG + Sbjct: 71 GKLPKDKADLIVQAAEEVSKGLLDEHFPLHVWQTGSGTQSNMNANEVISNRAIELAGGTL 130 Query: 149 GSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207 GSK +HPN+H N SQSSNDTFPT MHIAA++ +L+P + NL++ AK F +I+ Sbjct: 131 GSKSPIHPNDHVNMSQSSNDTFPTAMHIAAAIAFNEKLLPAVRNLRHVFAAKMDAFKNII 190 Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267 KIGRTHLQDA PLTLGQEFSGYV Q++ + R+ L L LA GGTAVGTGLNT P F Sbjct: 191 KIGRTHLQDAVPLTLGQEFSGYVAQLDACVHRLEEVLPELYELAAGGTAVGTGLNTHPQF 250 Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327 VK+AE I+K T L F TAPNKF ALA+H+ +V GA+ TLAC+L KIA DIR+L SGP Sbjct: 251 AVKVAEHIAKITKLPFVTAPNKFAALASHEPLVHAHGAMKTLACALMKIANDIRWLASGP 310 Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387 RCG EL++PENEPGSSIMPGKVNPTQ EA+T VC QV+GN+ A+ A SQG FELNVFK Sbjct: 311 RCGIGELIIPENEPGSSIMPGKVNPTQCEAMTMVCAQVLGNDTAVGIADSQGNFELNVFK 370 Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447 PV+I N+L+S+ L+ D+ +SF+ C EGI+ N+P I L SLMLVTALN IGYD A+ Sbjct: 371 PVIIFNVLHSLNLLADSCHSFQEFCAEGIEPNQPVIDYYLHHSLMLVTALNQHIGYDKAA 430 Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488 K+AK AH I+L+E+A++LG+LT ++F E+V PE M+ P+ Sbjct: 431 KIAKTAHHDNISLQEAAVKLGILTAEQFAEFVKPEKMISPE 471 >3TV2-A nrPDB Length = 459 Score = 558 bits (1437), Expect = e-159, Method: Compositional matrix adjust. Identities = 275/459 (59%), Positives = 337/459 (73%), Gaps = 3/459 (0%) Query: 29 RTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESL 88 R E D FGEI VPA + WGAQTQRS QNFKI + E+ L+HA ++K++AA VN L Sbjct: 1 RMERDTFGEIAVPAARLWGAQTQRSLQNFKI--STEKQSPELIHALALIKRAAAAVNLEL 58 Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148 G L + AI AADE+ +G+ D FPL V+QTGSGTQ+NMN NEVI+NRA E+LGG+ Sbjct: 59 GVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGER 118 Query: 149 G-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207 G S+ VHPN+ N+ QSSND FPT MHIAA+ I + L+P L L+ L+AK+ F IV Sbjct: 119 GESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIV 178 Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267 KIGRTHLQDATPLTLGQEFSGYV Q++ GI+ V +L L LAQGGTAVGTGLN P F Sbjct: 179 KIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKF 238 Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327 +A +I + TGL F +APNKFE +AA DA+V GAL T+A SL KIA DIR+L SGP Sbjct: 239 AAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGP 298 Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387 RCG EL +PENEPGSSIMPGKVNPTQ+EA+T +C QV GN+ A+ F G+ G FELNVF+ Sbjct: 299 RCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFR 358 Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447 P++ N+L S+RL+ D A F HC GI+ N RI LL +SLMLVTALNP IGYD A+ Sbjct: 359 PMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAA 418 Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486 ++AK AHK+G TLK +AL LG +T+ +FDEWV PEHM+G Sbjct: 419 QIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG 457 >1FUP-A nrPDB Length = 472 Score = 542 bits (1396), Expect = e-154, Method: Compositional matrix adjust. Identities = 270/462 (58%), Positives = 345/462 (74%), Gaps = 3/462 (0%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85 ++ R+E D+ G I VPADK WGAQTQRS ++F+I + E+MP L+HA + K++AA VN Sbjct: 2 NTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRI--STEKMPTSLIHALALTKRAAAKVN 59 Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145 E LG L + + AI+QAADEV +G+ DD FPL ++QTGSGTQSNMN NEV++NRA E+LG Sbjct: 60 EDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLG 119 Query: 146 GKIG-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204 G G ++VHPN+ N+SQSSND FPT MH+AA L ++ +LIP+L L L KS+ F Sbjct: 120 GVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFA 179 Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264 IVKIGRTHLQDATPLTLGQE SG+V +E+ ++ + +SL ++ LA GGTAVGTGLNT Sbjct: 180 DIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTH 239 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 P + ++A++++ T F TAPNKFEALA DA+V+ GAL LA SL KIA D+R+L Sbjct: 240 PEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLA 299 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384 SGPRCG E+ +PENEPGSSIMPGKVNPTQ EALT +C QVMGN+ AI G+ G FELN Sbjct: 300 SGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELN 359 Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444 VF+P++I N L S+RL+ D SF HC GI+ N RI++LL +SLMLVTALN IGYD Sbjct: 360 VFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYD 419 Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486 A+++AK AHK+G+TLK +AL LG L+E EFD WV PE M+G Sbjct: 420 KAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMVG 461 >1VDK-A nrPDB Length = 466 Score = 533 bits (1374), Expect = e-152, Method: Compositional matrix adjust. Identities = 262/460 (56%), Positives = 324/460 (70%) Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNES 87 +R E D GE+ VPADKYWGAQTQRS +NF+IG R RMPL ++ A+G+LKK+AA N Sbjct: 3 YRIERDTMGEVRVPADKYWGAQTQRSLENFRIGTDRFRMPLEIIRAYGMLKKAAARANLE 62 Query: 88 LGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGK 147 LG L +I+KAI QAA+EV GK DDHFPLVVFQTGSGTQ+NMN NEVI+NRA EILG Sbjct: 63 LGELPEEIAKAIIQAAEEVVQGKWDDHFPLVVFQTGSGTQTNMNVNEVIANRASEILGKP 122 Query: 148 IGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207 +GSK HPN+H N+ QSSNDTFPT M++A +L + L P + L AK++ FD IV Sbjct: 123 LGSKYAHPNDHVNRGQSSNDTFPTAMYVAVALALHQRLYPAVEGLIRTFTAKAQAFDQIV 182 Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267 K+GRTHL DA P+TLGQE + Q++ + V K L LA GGTAVGTGLN P F Sbjct: 183 KVGRTHLMDAVPITLGQEIGSWAAQLKTTLAAVKEMEKGLYNLAIGGTAVGTGLNAHPRF 242 Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327 +A+ +++ETGL F+ A N+F ALAAHD +V GA+ TLA +L KI D+R+L SGP Sbjct: 243 GELVAKYLAEETGLPFRVAENRFAALAAHDELVNVMGAIRTLAGALMKIGNDVRWLASGP 302 Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387 G E+ +P NEPGSSIMPGKVNPTQ EALT V V+V GN+ + FAGSQG F+LNV+K Sbjct: 303 YAGIGEITIPANEPGSSIMPGKVNPTQVEALTMVVVRVYGNDHTVAFAGSQGNFQLNVYK 362 Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447 PVM + L SI L+ DA SF H +GI+ N RI E L K+ ML TALN IGYD A+ Sbjct: 363 PVMAYSTLESINLLADAVASFDAHLAQGIEPNLERIEEYLQKNPMLATALNKAIGYDKAA 422 Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 ++ K A K+ TLK++ALELG LTE+EFD VVP + P Sbjct: 423 EIVKKALKEKKTLKQAALELGYLTEEEFDRIVVPMRLAKP 462 >3RD8-A nrPDB Length = 489 Score = 424 bits (1090), Expect = e-119, Method: Compositional matrix adjust. Identities = 232/448 (51%), Positives = 297/448 (66%), Gaps = 11/448 (2%) Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG-GARERMPLPLVHAFGVLKKSAAIVNE 86 +R E D GE+ VP D W AQTQR+ +NF I ER + A G+LK + A VN+ Sbjct: 29 YRIEHDTMGEVRVPKDALWRAQTQRAVENFPISFRGLERTQ---IRALGLLKAACAQVNK 85 Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146 LG LDP+ + AI AA E+A GK DD FP+ VFQTGSGT SNMN NEVI++ A Sbjct: 86 DLGLLDPEKADAIIAAAGEIAEGKHDDQFPIDVFQTGSGTSSNMNTNEVIASIA------ 139 Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206 VHPN+H N SQSSNDTFPT HIAA+ LIP L L +L AK+K++ + Sbjct: 140 AANGVTVHPNDHVNMSQSSNDTFPTATHIAATEAAVRHLIPALEVLHASLAAKAKQWRTV 199 Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266 VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L LA GGTAVGTGLN G Sbjct: 200 VKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELAIGGTAVGTGLNAPEG 259 Query: 267 FDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325 F K+ E + ETGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR++GS Sbjct: 260 FGAKVVEVLVNETGLAELRTAVDSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGS 319 Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385 GP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAI F G+ G FELNV Sbjct: 320 GPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVACQVVGNDAAIAFGGASGAFELNV 379 Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445 + P+M NLL S L+++ + F C++G+ ANE R+ EL S +VT LN IGY+ Sbjct: 380 YIPMMARNLLESFTLLSNVSRLFAERCIDGLVANEERLRELAESSPSIVTPLNSAIGYEE 439 Query: 446 ASKVAKNAHKKGITLKESALELGVLTEK 473 A+KVAK A + T++++ ++ G++ +K Sbjct: 440 AAKVAKQALAEKKTIRQTVIDRGLIGDK 467 >3QBP-A nrPDB Length = 478 Score = 417 bits (1071), Expect = e-117, Method: Compositional matrix adjust. Identities = 228/451 (50%), Positives = 299/451 (66%), Gaps = 11/451 (2%) Query: 25 NSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAI 83 ++ +R E D GE+ VPA W AQTQR+ +NF I G ER + A G+LK + A Sbjct: 16 DTEYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERAQ---IRALGLLKGACAQ 72 Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143 VN LG L P+ ++AI AA E+A G+ DD FP+ VFQTGSGT SNMN NEVI++ Sbjct: 73 VNMDLGLLAPEKAEAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIAS----- 127 Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEF 203 + G G VHPN+ N SQSSNDTFPT HIAA+ + LIP L L++AL K+ E+ Sbjct: 128 IAGANGVA-VHPNDDVNMSQSSNDTFPTATHIAATEAAVSHLIPALEILQDALATKALEW 186 Query: 204 DHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNT 263 +VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV +L L LA GGTAVGTGLN Sbjct: 187 QSVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRATLPRLGELAIGGTAVGTGLNA 246 Query: 264 KPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 GF VK+ + +TGL + +TA N FEA AA D +VE SGAL T+A SL KIA DIR+ Sbjct: 247 PEGFGVKVVSVLVSQTGLPQLRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRW 306 Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 +GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AA+ + G+ G FE Sbjct: 307 MGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAVAWGGANGAFE 366 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 LNV+ P+M N+L S L+T+ + F C+ G+ AN + EL S +VT LN IG Sbjct: 367 LNVYIPMMARNILESFTLLTNVSKLFAQRCIAGLTANAEHLRELAESSPSIVTPLNSAIG 426 Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTEK 473 Y+ A+ VAK A K+ T++++ ++ G++ +K Sbjct: 427 YEEAAAVAKQALKERKTIRQTVIDRGLIGDK 457 >4ADL-A nrPDB Length = 495 Score = 412 bits (1059), Expect = e-115, Method: Compositional matrix adjust. Identities = 225/465 (48%), Positives = 301/465 (64%), Gaps = 11/465 (2%) Query: 11 TFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLP 69 + K + + + ++++R E D GE+ VPA W AQTQR+ +NF I G ER Sbjct: 15 SLYKKAGSMAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQ-- 72 Query: 70 LVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSN 129 + A G+LK + A VN LG L P+ + AI AA E+A G+ DD FP+ VFQTGSGT SN Sbjct: 73 -IRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSN 131 Query: 130 MNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPEL 189 MN NEVI++ A + G +HPN+ N SQSSNDTFPT HIAA+ LIP L Sbjct: 132 MNTNEVIASIAAK------GGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPAL 185 Query: 190 TNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSF 249 L +AL AK+ ++ +VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV L L Sbjct: 186 QQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGE 245 Query: 250 LAQGGTAVGTGLNTKPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNT 308 LA GGTAVGTGLN F V++ + +TGL + +TA N FEA AA D +VE SGAL T Sbjct: 246 LAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRT 305 Query: 309 LACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGN 368 +A SL KIA DIR++GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN Sbjct: 306 IAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGN 365 Query: 369 NAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLT 428 +AAI + G+ G FELNV+ P+M N+L S +L+T+ + F C+ G+ AN + L Sbjct: 366 DAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAE 425 Query: 429 KSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEK 473 S +VT LN IGY+ A+ VAK A K+ T++++ ++ G++ ++ Sbjct: 426 SSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDR 470 >3R6Q-A nrPDB Length = 468 Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust. Identities = 203/465 (43%), Positives = 297/465 (63%), Gaps = 4/465 (0%) Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83 MN+ R E D GE +P D Y+G QT R+ +NF I G R + L+ + G++KKSAA+ Sbjct: 1 MNTDVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYR--IHPELIKSLGIVKKSAAL 58 Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143 N +G LD ++ + I +AADEV GK +D F + Q G+GT NMNANEVI+NRA+E+ Sbjct: 59 ANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALEL 118 Query: 144 LGGKIGS-KQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKE 202 +G + G+ ++ PN+H N SQS+ND FPT HIA L + N+LI ++ K+ E Sbjct: 119 MGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAV-LSLLNQLIETTKYMQQEFMKKADE 177 Query: 203 FDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLN 262 F ++K+GRTHLQDA P+ LGQEF Y + + I+R+A++ L + G TAVGTGLN Sbjct: 178 FAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLN 237 Query: 263 TKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 P + + E ++K +G ++A + +A D E S AL ++ KIA D+R Sbjct: 238 ADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRL 297 Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 + SGPR G E++LP +PGSSIMPGKVNP E + QV QV GN+ IT A GQFE Sbjct: 298 MASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFE 357 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 LNV +PV+ NL+ SI ++T+ SF +C++GIKANE R+ E + KS+ ++TA+NP +G Sbjct: 358 LNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEERMKEYVEKSIGIITAINPHVG 417 Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 Y+ A+K+A+ A+ G +++E ++ GVLTE++ +E + P M+ P Sbjct: 418 YETAAKLAREAYLTGESIRELCIKYGVLTEEQLNEILNPYEMIHP 462 >3RRP-A nrPDB Length = 471 Score = 400 bits (1028), Expect = e-112, Method: Compositional matrix adjust. Identities = 228/448 (50%), Positives = 294/448 (65%), Gaps = 9/448 (2%) Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAIVNE 86 +R E D GE+ VPA+ W AQTQR+ +NF I G ER + A G+LK + A VN+ Sbjct: 11 YRIEHDTMGEVRVPAEALWRAQTQRAVENFPISGRGLERTQ---IRALGLLKGACAQVNK 67 Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146 LG L + + AI AA E+A GK DD FP+ VFQTGSGT SNMNANEVI++ A + Sbjct: 68 DLGLLAAEKADAIIAAAQEIADGKHDDQFPIDVFQTGSGTSSNMNANEVIASIAAQATPP 127 Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206 + VHPN+ N SQSSNDTFPT H+AA+ +LIP L L+ AL K+K + + Sbjct: 128 VV----VHPNDDVNMSQSSNDTFPTATHLAATEAAVRDLIPALEYLQQALATKAKAWKTV 183 Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266 VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L L GGTAVGTGLN G Sbjct: 184 VKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELPIGGTAVGTGLNAPDG 243 Query: 267 FDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325 F K+ E + + TGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR++GS Sbjct: 244 FGAKVVEVLKQSTGLSELKTASDSFEAQAARDGLVEGSGALKTIAASLTKIANDIRWMGS 303 Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385 GP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAIT G G FELNV Sbjct: 304 GPLTGLGEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAITVGGLSGAFELNV 363 Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445 + PVM NLL S L+ + + F CV+G+ ANE + L S +VT LN IGY+ Sbjct: 364 YIPVMARNLLESFTLLANVSRLFVDKCVDGLVANEDHLRTLAESSPSIVTPLNSAIGYEE 423 Query: 446 ASKVAKNAHKKGITLKESALELGVLTEK 473 A+ VAK A K+ T++++ ++ G++ +K Sbjct: 424 AAAVAKEALKERKTIRQTVIDRGLIGDK 451 >3OCE-A nrPDB Length = 474 Score = 335 bits (858), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 190/447 (42%), Positives = 266/447 (59%), Gaps = 6/447 (1%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAIV 84 S R E D+ GE +P D Y+G QT R+ +NF + A +P LV A ++KK+AA Sbjct: 4 SMTRREQDSLGERDIPMDAYFGIQTLRAVENFSLSDVALNHIP-ALVRALAMVKKAAATA 62 Query: 85 NESLGGL-DPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143 N L L +PK + AI A D++ G L + F + VFQ G+GT SNMNANEVI+NRA+E Sbjct: 63 NYKLRQLPEPKYA-AIVAACDDIIDGLLMEQFVVDVFQGGAGTSSNMNANEVIANRALEH 121 Query: 144 LGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKE 202 LG G Q +HPN+ N SQS+ND +PT + +A L QN++ L L A EAK +E Sbjct: 122 LGRPRGDYQTIHPNDDVNMSQSTNDVYPTAVRLALLLS-QNQVQTALHRLIAAFEAKGRE 180 Query: 203 FDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLN 262 F ++KIGRT LQDA P+TLGQEF + + R+ + GGTA+GT +N Sbjct: 181 FATVIKIGRTQLQDAVPITLGQEFEAFAATLREDTARLEEVAALFREVNLGGTAIGTRIN 240 Query: 263 TKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 + + ++S+ +G++ + N EA A V SG L +A L KIA D+R Sbjct: 241 ASHAYAEQAIVELSQISGIELKATGNLVEASWDTGAFVTFSGILRRIAVKLSKIANDLRL 300 Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 L SGPR G E+ LP +PGSSIMPGKVNP E++ QVC QV+GN+ +T A GQ + Sbjct: 301 LSSGPRSGLGEIRLPAVQPGSSIMPGKVNPVIPESVNQVCYQVIGNDLTVTMAAESGQLQ 360 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 LN F+P+++ N+L+S+RL+ A + CV+GI+AN R +S+ L TAL P +G Sbjct: 361 LNAFEPLIVYNILSSMRLLGRAMTNLAERCVDGIEANVERCRAGAEESISLATALVPVVG 420 Query: 443 YDAASKVAKNAHKKGITLKESALELGV 469 Y A+++AK A G T+ E A+ G+ Sbjct: 421 YARAAEIAKQALASGQTVMEVAISKGL 447 >1JSW-A nrPDB Length = 478 Score = 311 bits (798), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 182/470 (38%), Positives = 272/470 (57%), Gaps = 11/470 (2%) Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83 M+++ R E D G VPAD Y+G T R+ +NF I + V ++KK+AA+ Sbjct: 1 MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAM 60 Query: 84 VNESLGGLDPKISKAIQQAADEVAS-GKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIE 142 N+ L + ++ AI A DEV + GK D FP+ V+Q G+GT NMN NEV++N +E Sbjct: 61 ANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLE 120 Query: 143 ILGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201 ++G + G Q ++PN+H N+ QS+ND +PT IA + +L+ + L+ E K+ Sbjct: 121 LMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLI-KLVDAINQLREGFERKAV 179 Query: 202 EFDHIVKIGRTHLQDATPLTLGQEFSGYV----QQVENGIQRVAHSLKTLSFLAQGGTAV 257 EF I+K+GRT LQDA P+TLGQEF + ++V+N IQR A L ++ G TA+ Sbjct: 180 EFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKN-IQRTAELLLEVNL---GATAI 235 Query: 258 GTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIA 317 GTGLNT + +++++ TG A + EA + A V GAL LA + KI Sbjct: 236 GTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKIC 295 Query: 318 QDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGS 377 D+R L SGPR G +E+ LPE + GSSIMP KVNP E + QVC +V+GN+ +T A Sbjct: 296 NDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAE 355 Query: 378 QGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTAL 437 GQ +LNV +PV+ + S+ ++T+A Y+ C+ GI AN+ + S+ +VT L Sbjct: 356 AGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYL 415 Query: 438 NPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 NP IG+ V K + G +++E LE G+LTE E D+ ++++ P Sbjct: 416 NPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHP 465 >5EYT-A nrPDB Length = 497 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 77/330 (23%), Positives = 144/330 (43%), Gaps = 40/330 (12%) Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH 242 N L+P++ + L K+ ++ + RTHLQ A P T+G+ ++Q + ++ + Sbjct: 140 NILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLER 199 Query: 243 SLK-TLSFLAQGGTAVGTGLNTKPGFD------VKIAEQISKETGLKF------QTAPNK 289 T+ F G AVGT + F +K+ E ++K++G + QT P K Sbjct: 200 LKNHTIRFRGAKG-AVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRK 258 Query: 290 FEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMP 347 + +E + AL+ + ++ KI DIR L S +HE+ P + GSS MP Sbjct: 259 VD--------IEITNALSNIGATVHKICTDIRLLSS-----FHEVEEPFETKQIGSSAMP 305 Query: 348 GKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYS 407 K NP ++E + +M + ++ S E ++ + +L L DA + Sbjct: 306 YKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLT 365 Query: 408 FRVHCVEGIKANEPRIHELLTKS---LMLVTALNPKIGYDAAS-------KVAKNAHKKG 457 + EG+ P + E S ++V + K+ + A+ ++ K++H+ Sbjct: 366 LLQNIAEGLIVY-PMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAA 424 Query: 458 ITLKESALELGVLTEKEFDEWVVPEHMLGP 487 +K L+ ++ + D + P H L P Sbjct: 425 AEIKLKGLKNSLMDKLLNDYYFAPIHSLLP 454 >1RE5-A nrPDB Length = 450 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 94/380 (24%), Positives = 149/380 (39%), Gaps = 40/380 (10%) Query: 131 NANEVISNRAIEI---LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELI- 186 NA N AI + LG I + + + +S D T + LQ+++ L Sbjct: 69 NAIATAGNSAIPLVKALGKVIATGVPEAERYVHLGATSQDAMDTGL----VLQLRDALDL 124 Query: 187 --PELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH-- 242 +L L + L ++ + +GRT LQ ATP+TLG + +G + + QR+ Sbjct: 125 IEADLGKLADTLSQQALKHADTPLVGRTWLQHATPVTLGMKLAGVLGALTRHRQRLQELR 184 Query: 243 -SLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVE 301 L L F G+ G P +AE ++++ L P + D +VE Sbjct: 185 PRLLVLQFGGASGSLAALGSKAMP-----VAEALAEQLKLTLPEQPWHTQ----RDRLVE 235 Query: 302 CSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQV 361 + L +A SL K +DI L E P + GSS MP K NP L Sbjct: 236 FASVLGLVAGSLGKFGRDISLLMQTEAGEVFEPSAP-GKGGSSTMPHKRNPVGAAVLIGA 294 Query: 362 CVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEP 421 +V G + + FA + E ++ L I + A EG++ + Sbjct: 295 ATRVPGLLSTL-FAAMPQEHERSLGLWHAEWETLPDICCLVSGALRQAQVIAEGMEVDAA 353 Query: 422 RIHE--LLTKSLMLVTA----LNPKIGYDAA---------SKVAKNAHKKGITLKESALE 466 R+ LT+ L+L A L ++G D A VA+ H + + E + Sbjct: 354 RMRRNLDLTQGLVLAEAVSIVLAQRLGRDRAHHLLEQCCQRAVAEQRHLRAVLGDEPQVS 413 Query: 467 LGVLTEKEFDEWVVPEHMLG 486 L+ +E D + P H LG Sbjct: 414 -AELSGEELDRLLDPAHYLG 432 >2PFM-A nrPDB Length = 444 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 12/205 (5%) Query: 164 SSNDTFPTVMHIAASLQIQNELI-PELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTL 222 +S D T + + L+ NE+I +L N + L K+KE + + +GRTH A P T Sbjct: 104 TSTDVVDTAL--SYILKQANEIILKDLENFVSILANKAKEHKYTIMMGRTHGVHAEPTTF 161 Query: 223 GQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLK 282 G + + ++++ ++R + T+ G AVGT N P + + E L Sbjct: 162 GLKLGLWYEEMKRNVERFKQAANTVRVGKLSG-AVGTYANIDPFVEKYVCE------NLG 214 Query: 283 FQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPG 342 + AP + L D L +A S+ K+A +IR L E + + G Sbjct: 215 LEAAPISTQTL-QRDRHAHYMSTLALIATSIEKMAVEIRGLQKSETREVEE-AFAKGQKG 272 Query: 343 SSIMPGKVNPTQNEALTQVCVQVMG 367 SS MP K NP +E +T + + G Sbjct: 273 SSAMPHKRNPIGSENMTGLARVIRG 297 >1TJ7-A nrPDB Length = 457 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 72/320 (22%), Positives = 130/320 (40%), Gaps = 27/320 (8%) Query: 146 GKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205 GK+ K + +S ND T + + + +EL+ L++AL ++ Sbjct: 90 GKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTV-SELLTANRQLQSALVETAQNNQD 148 Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKP 265 V G THLQ A P+T YV+ + R+ +LK L + +G G Sbjct: 149 AVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDV-----SPLGCGALAGT 203 Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325 +++ EQ++ G T N ++++ D ++E A L + A+D+ + + Sbjct: 204 AYEID-REQLAGWLGFASAT-RNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNT 261 Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMG--NNAAITFAGSQGQFEL 383 G G+ EL GSS+MP K NP E + C +V G +T G + Sbjct: 262 G-EAGFVELS-DRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNK 319 Query: 384 NVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGY 443 ++ + L +++ D + ++GI+ PR E + GY Sbjct: 320 DMQEDK--EGLFDALDTWLDCLH-MAALVLDGIQVKRPRCQEAAQQ------------GY 364 Query: 444 DAASKVAKNAHKKGITLKES 463 A+++A KG+ +E+ Sbjct: 365 ANATELADYLVAKGVPFREA 384 >4MX2-A nrPDB Length = 480 Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 61/202 (30%), Positives = 96/202 (47%), Gaps = 23/202 (11%) Query: 162 SQSSNDT-FPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPL 220 SQ N+T P ++ A + + IP L L L++K E+D + + RTH Q A+P Sbjct: 150 SQDINNTSIPMLLRDA----LHHHYIPTLDQLIALLKSKLPEWD-VPMLARTHGQPASPT 204 Query: 221 TLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVG---TGLNTKPGFD-VKIAEQ-I 275 L +EF +++++E QR L ++ + G A G L PG + + E + Sbjct: 205 NLAKEFMVWIERLEE--QRTM--LLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFL 260 Query: 276 SKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDI-RYLGSGPRCGYHEL 334 SK GL+ Q + E AI + L+T+ L +A+D+ +Y+ GY + Sbjct: 261 SKYLGLRRQRYTTQIEHYDNLAAICDACARLHTI---LMDLAKDVWQYIS----LGYFDQ 313 Query: 335 MLPENEPGSSIMPGKVNPTQNE 356 + E GSS MP KVNP E Sbjct: 314 KVRAGEVGSSAMPHKVNPIDFE 335 >1F1O-A nrPDB Length = 431 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 51/188 (27%), Positives = 86/188 (45%), Gaps = 9/188 (4%) Query: 180 QIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQR 239 Q + L+ +L + ++ K+KE + V +GRTH A P T G + + + ++++ ++R Sbjct: 108 QANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWHEEMKRNLER 167 Query: 240 VAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAI 299 + + G AVGT N P + + E++ GLK AP + L D Sbjct: 168 FKQAKAGIEVGKISG-AVGTYANIDPFVEQYVCEKL----GLK--AAPISTQTL-QRDRH 219 Query: 300 VECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALT 359 + L +A S+ K A +IR L E + + GSS MP K NP +E +T Sbjct: 220 ADYMATLALIATSIEKFAVEIRGLQKSETREVEEF-FAKGQKGSSAMPHKRNPIGSENMT 278 Query: 360 QVCVQVMG 367 + + G Sbjct: 279 GMARVIRG 286 >2E9F-A nrPDB Length = 462 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 85/344 (24%), Positives = 138/344 (40%), Gaps = 63/344 (18%) Query: 155 PNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKI-GRTH 213 P + ++S ND T + + I L L + + K D + + G TH Sbjct: 100 PGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTH 159 Query: 214 LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIA 272 LQ A P+ L F Y + ++ R+ + + L+ G A+ GTG F Sbjct: 160 LQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHF----- 214 Query: 273 EQISKETGLKFQTAP--NKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCG 330 ++E G K AP N +A+A+ D +E ALN L ++A+++ L S G Sbjct: 215 --TARELGFK---APMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEEL-ILYSTEEFG 268 Query: 331 YHELMLPEN-EPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPV 389 + E+ P+ GSSIMP K NP E + +V+G F G V K + Sbjct: 269 FVEV--PDAFATGSSIMPQKKNPDILELIRAKAGRVLG-----AFVGLSA-----VVKGL 316 Query: 390 MIA---NLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI----- 441 +A +L + DA ++R SL L+ AL P + Sbjct: 317 PLAYNKDLQEDKEPLLDALATYR-------------------DSLRLLAALLPGLKWRRE 357 Query: 442 --------GYDAASKVAKNAHKKGITLKESALELGVLTEKEFDE 477 GY A+++A +KG+ +E+ +G L + +E Sbjct: 358 RMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEE 401 >3BHG-A nrPDB Length = 459 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 53/199 (26%), Positives = 78/199 (39%), Gaps = 12/199 (6%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 C +N + ++ A + IQ P + + ++ K+ + + RTH Q AT Sbjct: 124 CTSEDINNLAYALMIKQAIAQVIQ----PTIAEIMGSITLLGKQHADVAMLSRTHGQPAT 179 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277 P T+G+E +V +++ Q++A L F G + P D K Sbjct: 180 PTTMGKELVNFVARLKRPQQQLAEVLIPAKFNGAVGN-YNAHVAAYPEVDWRKHCANFVT 238 Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337 GL F + E HD I E S + + L QDI S GY + Sbjct: 239 SLGLSFNAYTTQIE---PHDGIAEVSQIMVRINNILLDYTQDI---WSYISLGYFKQKTI 292 Query: 338 ENEPGSSIMPGKVNPTQNE 356 E GSS MP KVNP E Sbjct: 293 AEEVGSSTMPHKVNPIDFE 311 >2X75-A nrPDB Length = 431 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 90/344 (26%), Positives = 137/344 (39%), Gaps = 44/344 (12%) Query: 168 TFPTVMHIAASLQIQ--NELIP-ELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQ 224 T V+ A S I+ N++I +L + L K+K + + + +GRTH A P T G Sbjct: 93 TSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGV 152 Query: 225 EFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQ 284 + + + +++ +QR + + G AVGT N P +I + K G+ Sbjct: 153 KMALWYTEMQRNLQRFKQVREEIEVGKMSG-AVGTFANIPP----EIESYVCKHLGIG-- 205 Query: 285 TAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSS 344 TAP + L D L +A SL K A +IR L E + + GSS Sbjct: 206 TAPVSTQTLQ-RDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEE-AFAKGQKGSS 263 Query: 345 IMPGKVNPTQNEALTQVCVQVMGNNAAITFAG-----------SQGQFELNVFKPVMIA- 392 MP K NP +E +T + + G IT A S E + V IA Sbjct: 264 AMPHKRNPIGSENITGISRVIRG---YITTAYENVPLWHERDISHSSAERIMLPDVTIAL 320 Query: 393 -NLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI----GYDAA- 446 LN I D F + ++ N + L+ +L+ +N + YD Sbjct: 321 DYALNRFTNIVDRLTVFE----DNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQ 376 Query: 447 -----SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485 S K ++ I ES VLT++E DE P+H L Sbjct: 377 PKAMISWETKTPFRELIEQDESIT--SVLTKEELDECFDPKHHL 418 >1C3C-A nrPDB Length = 429 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 48/177 (27%), Positives = 79/177 (44%), Gaps = 13/177 (7%) Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244 L+ L + L + + H IGRTH A P + G + G+ +++ +QR+ ++ Sbjct: 112 LLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAI 171 Query: 245 KTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSG 304 + +S+ G AVG N P ++ E+ GLK + + + D Sbjct: 172 EEVSYGKISG-AVGNYANVPP----EVEEKALSYLGLKPEPVSTQ---VVPRDRHAFYLS 223 Query: 305 ALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEALT 359 L +A + +IA +IR+L R E+ P + + GSS MP K NP E LT Sbjct: 224 TLAIVAAGIERIAVEIRHL---QRTEVLEVEEPFRKGQRGSSAMPHKKNPITCERLT 277 >1Q5N-A nrPDB Length = 454 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 67/268 (25%), Positives = 117/268 (43%), Gaps = 28/268 (10%) Query: 90 GLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIG 149 G+ P+ + + Q A + A K+D T +G N+ V AI + Sbjct: 45 GVIPQSAATVIQRAAKTAIDKID----FDALATATGLAGNIAIPFVKQLTAIVKDADEDA 100 Query: 150 SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALE---AKSKEFDHI 206 ++ VH +S D T A LQ ++ L ++ E ++++ + H Sbjct: 101 ARYVHWGA------TSQDILDT----ACILQCRDALAIVQNQVQQCYETALSQAQTYRHQ 150 Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266 V +GRT LQ A P+TLG + + + + + R+ +++K +AQ G AVG+ + + Sbjct: 151 VMMGRTWLQQALPITLGHKLARWASAFKRDLDRI-NAIKARVLVAQLGGAVGSLASLQDQ 209 Query: 267 FDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSG 326 + + E +K+ L QTA D IVE + L + ++ K+A+D + Sbjct: 210 GSI-VVEAYAKQLKLG-QTACTWH---GERDRIVEIASVLGIITGNVGKMARDWSLM--- 261 Query: 327 PRCGYHELMLP--ENEPGSSIMPGKVNP 352 + E+ P + GSS MP K NP Sbjct: 262 MQTEIAEVFEPTAKGRGGSSTMPHKRNP 289 >4EEI-A nrPDB Length = 438 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 51/199 (25%), Positives = 90/199 (45%), Gaps = 20/199 (10%) Query: 168 TFPTVMHIAASLQIQNEL---IPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQ 224 T ++ A SLQI++ + I +L L ++L K++E I+ +GR+H A P++ GQ Sbjct: 93 TSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQ 152 Query: 225 EFSGYVQQVENGIQRVAHSLK---TLSFL-AQGGTAVGTGLNTKPGFDVKIAEQISKETG 280 +F G + + ++ + K T+ F A G + T + K D+ G Sbjct: 153 KFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADI---------LG 203 Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENE 340 L + + + D I + +A ++ ++A +IR+L +E + + Sbjct: 204 LPVEEVSTQ---VIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYE-GFSKGQ 259 Query: 341 PGSSIMPGKVNPTQNEALT 359 GSS MP K NP E LT Sbjct: 260 KGSSTMPHKKNPISTENLT 278 >4EFC-A nrPDB Length = 472 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 52/199 (26%), Positives = 88/199 (44%), Gaps = 17/199 (8%) Query: 162 SQSSNDT-FPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPL 220 SQ N+T P ++ A I +P L + +L +K ++D + + RTH Q A+P Sbjct: 139 SQDINNTAIPMMIRDA----IVTLYLPALDGIIGSLTSKLVDWD-VPMLARTHGQPASPT 193 Query: 221 TLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQ--ISKE 278 L +EF +++++ +++ T F G L P + + ++K Sbjct: 194 NLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGN-FNAHLVAYPSVNWRAFADMFLAKY 252 Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDI-RYLGSGPRCGYHELMLP 337 GLK Q A + E +D + A L L + +D+ +Y+ G+ + + Sbjct: 253 LGLKRQQATTQIEN---YDHLAALCDACARLHVILIDMCRDVWQYIS----MGFFKQKVK 305 Query: 338 ENEPGSSIMPGKVNPTQNE 356 E E GSS MP KVNP E Sbjct: 306 EGEVGSSTMPHKVNPIDFE 324 >3C8T-A nrPDB Length = 451 Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 55/215 (25%), Positives = 93/215 (43%), Gaps = 13/215 (6%) Query: 172 VMHIAASLQIQNELI---PELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSG 228 +M A LQI++ L + +++ AL A ++ GRTHLQ A P+T G + + Sbjct: 107 IMDTATVLQIRDGLALISRRIESVRKALAALARNHRDTPMAGRTHLQHALPVTFGYKAAV 166 Query: 229 YVQQVENGIQRVAH-SLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAP 287 ++ + R+ S + L G + L T+ G DV+ ++++E L + Sbjct: 167 WLSAFDRHAARLEEISPRVLVVEFSGASGTLASLGTR-GLDVQ--RELARELNLGVPSIT 223 Query: 288 NKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMP 347 +A DA+ E L ++ SL K+A DI + + E + + SS MP Sbjct: 224 WH----SARDAVAETVQFLALVSGSLGKLAMDISIMMTTELGEVAEPFV-RHRGASSTMP 278 Query: 348 GKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 K NP E L +++ N+A FE Sbjct: 279 QKQNPVSCE-LILAGARIVRNHATSMLDAMIHDFE 312 >5E3V-A nrPDB Length = 380 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 48/180 (26%), Positives = 77/180 (42%), Gaps = 22/180 (12%) Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244 ++P + NA++ + ++ I + RTH Q ATP TLG+E + ++E R L Sbjct: 157 ILPYWRQVINAVKDLATQYRDIPLLSRTHGQPATPSTLGKEMANVAYRME----RQFRQL 212 Query: 245 KTLSFLAQGGTAVG---TGLNTKPGFDV-KIAEQISKETGLKFQTAPNKFEALAAHDAIV 300 + L + AVG + P D + +E+ G+++ + E HD I Sbjct: 213 NQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIE---PHDYIA 269 Query: 301 E---CSGALNTLACSLFKIAQDIR-YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNE 356 E C NT+ L +D+ Y+ + + E GSS MP KVNP E Sbjct: 270 ELFDCIARFNTI---LIDFDRDVWGYIA----LNHFKQKTIAGEIGSSTMPHKVNPIDFE 322 >2J91-A nrPDB Length = 503 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 12/188 (6%) Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244 L+P+L + + L +KE + +G TH Q A T+G+ ++Q + +Q + Sbjct: 153 LLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVR 212 Query: 245 KTLSFLAQGGT--AVGTGLNTKPGFDVKIAEQISKETGLK--FQTAPNKFEALAAHDAIV 300 L F GT + L G D K+ EQ+ K K F+ A + Sbjct: 213 DDLRFRGVKGTTGTQASFLQLFEGDDHKV-EQLDKMVTEKAGFKRAFIITGQTYTRKVDI 271 Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEAL 358 E L +L S+ KI DIR L + E+ P + + GSS MP K NP ++E Sbjct: 272 EVLSVLASLGASVHKICTDIRLLAN-----LKEMEEPFEKQQIGSSAMPYKRNPMRSERC 326 Query: 359 TQVCVQVM 366 + +M Sbjct: 327 CSLARHLM 334 >4NSL-A nrPDB Length = 470 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 48/180 (26%), Positives = 77/180 (42%), Gaps = 22/180 (12%) Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244 ++P + NA++ + ++ I + RTH Q ATP TLG+E + ++E R L Sbjct: 157 ILPYWRQVINAVKDLATQYRDIPLLSRTHGQPATPSTLGKEMANVAYRME----RQFRQL 212 Query: 245 KTLSFLAQGGTAVG---TGLNTKPGFDV-KIAEQISKETGLKFQTAPNKFEALAAHDAIV 300 + L + AVG + P D + +E+ G+++ + E HD I Sbjct: 213 NQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIE---PHDYIA 269 Query: 301 E---CSGALNTLACSLFKIAQDIR-YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNE 356 E C NT+ L +D+ Y+ + + E GSS MP KVNP E Sbjct: 270 ELFDCIARFNTI---LIDFDRDVWGYIA----LNHFKQKTIAGEIGSSTMPHKVNPIDFE 322 >1I0A-A nrPDB Length = 466 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 63/248 (25%), Positives = 97/248 (39%), Gaps = 20/248 (8%) Query: 126 TQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNEL 185 TQS+ + I R E++G G Q +S N+ T + + I Sbjct: 82 TQSDEDIQTAIERRLKELIGDIAGKLQT--------GRSRNEQVVTDLKLLLKSSISVIS 133 Query: 186 IPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLK 245 L +K +E + E D I+ G THLQ A P+ Q + + +R+ K Sbjct: 134 THLLQLIKTLVERAAIEID-IIMPGYTHLQKALPIRWSQFLLSHAVALTRDSERLGEVKK 192 Query: 246 TLSFLAQG-GTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSG 304 ++ L G G G L E + E + T N +A++ D +VE Sbjct: 193 RITVLPLGSGVLAGNPLEIDR-------ELLRSELDMTSITL-NSIDAISERDFVVELIS 244 Query: 305 ALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQ 364 L L K+A+D+ + S G+ L GSS++P K NP E + + Sbjct: 245 VATLLMIHLSKLAEDL-IIFSTTEFGFVTLS-DAYSTGSSLLPQKKNPDSLELIRSKAGR 302 Query: 365 VMGNNAAI 372 V G AAI Sbjct: 303 VFGRLAAI 310 >2PTS-A nrPDB Length = 462 Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 22/180 (12%) Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244 ++P L + L+ + ++ I + RTH Q ATP T+G+E + ++E R L Sbjct: 143 ILPYWRQLIDGLKDLAVQYRDIPLLSRTHGQPATPSTIGKEMANVAYRME----RQYRQL 198 Query: 245 KTLSFLAQGGTAVG---TGLNTKPGFDV-KIAEQISKETGLKFQTAPNKFEALAAHDAIV 300 + L + AVG + P D + +E+ G+++ + E HD I Sbjct: 199 NQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIE---PHDYIA 255 Query: 301 E---CSGALNTLACSLFKIAQDIR-YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNE 356 E C NT+ L +D+ Y+ + + E GSS MP KVNP E Sbjct: 256 ELFDCVARFNTI---LIDFDRDVWGYIA----LNHFKQKTIAGEIGSSTMPHKVNPIDFE 308 >5V4L-A nrPDB Length = 479 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 45/195 (23%), Positives = 86/195 (44%), Gaps = 24/195 (12%) Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244 L+P+L + + L +K++ + +G TH Q A T+G+ + ++Q++ ++ + + Sbjct: 124 LLPKLATVISRLANFAKQYRDLPTLGFTHFQPAQLTTVGKRATLWIQELLWDLRNLQRAR 183 Query: 245 KTLSFLAQGGTAVGTGLNTKPGFD------VKIAEQISKETGLKF------QTAPNKFEA 292 L F GT GT + FD + +++++ G + QT K +A Sbjct: 184 DDLGFRGVKGT-TGTQASFLALFDGDHAKVEALDKRVTELFGFPYAYPVTGQTYSRKIDA 242 Query: 293 LAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNP 352 + G L++ ++ KIA DIR L + E +++ GSS M K NP Sbjct: 243 --------DVLGPLSSFGATVHKIATDIRLLANLKEI---EEPFEKDQIGSSAMAYKRNP 291 Query: 353 TQNEALTQVCVQVMG 367 + E + +M Sbjct: 292 MRCERACSLARHLMA 306 >1TJU-A nrPDB Length = 474 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 67/273 (24%), Positives = 119/273 (43%), Gaps = 27/273 (9%) Query: 104 DEVASG--KLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQ 161 +++ SG K+ + + VF + ANE R ++ L G I K H + Sbjct: 63 EKILSGLEKISEEWSKGVFVVKQSDEDIHTANE----RRLKELIGDIAGKL-----HTGR 113 Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLT 221 S++ + + SL I + + +L +K +E + E D I+ G +HLQ A P+ Sbjct: 114 SRNDQVVTDLKLFMKNSLSIISTHLLQL--IKTLVERAAIEIDVILP-GYSHLQKAQPIR 170 Query: 222 LGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGL 281 Q + + +R+ K ++ L G A+ G + I ++ + + L Sbjct: 171 WSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALA-------GNPLDIDREMLR-SEL 222 Query: 282 KFQT-APNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPEN- 339 +F + + N +A++ D +VE L L K+A+D+ + S G+ L L + Sbjct: 223 EFASISLNSMDAISERDFVVEFLSFATLLMIHLSKMAEDL-IIYSTSEFGF--LTLSDAF 279 Query: 340 EPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI 372 GSS+MP K NP E + +V G A+I Sbjct: 280 STGSSLMPQKKNPDSLELIRSKAGRVFGRLASI 312 >5XNZ-A nrPDB Length = 489 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 81/306 (26%), Positives = 122/306 (39%), Gaps = 43/306 (14%) Query: 210 GRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG--GTAVGT-GLNTKPG 266 GRT A P T G + +G+++ V RVA L F G GT G G T G Sbjct: 180 GRTLALHAVPTTFGLKAAGWLELVSEAAGRVARLRDGLPFSLGGAAGTLAGYFGDRTDRG 239 Query: 267 FDVKIAEQI----SKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 + +++ + ETGL P + L + + + L A +L KIA D++ Sbjct: 240 DPAVLLDRLLDAYAAETGLARPVLP--WHVL--RTPVADLAAVLAFTAGALGKIAVDVQS 295 Query: 323 LGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFA----- 375 L R E+ P E SS MP K NP + + +QV +T Sbjct: 296 LA---RTEVAEVAEPAVEGRGASSAMPHKRNPVLSTLIRSAALQVPALATGLTQCLVSED 352 Query: 376 -GSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELL------T 428 S G + ++P L +RL AA + V G++ + R+ L Sbjct: 353 ERSAGAWHAE-WQP-----LRECLRLTGGAARTA-VELAAGLEVDAARMRANLDLTDGRI 405 Query: 429 KSLMLVTALNPKIGYDAA----SKVAKNAHKKGITLKESALEL----GVLTEKEFDEWVV 480 S + AL P +G AA ++ A A +G TL E EL GVL ++ ++ + Sbjct: 406 VSESVAVALTPLLGRQAAKELLTRAAFTAGHEGRTLGEVLGELPELDGVLPKERWEALLD 465 Query: 481 PEHMLG 486 P G Sbjct: 466 PARATG 471 >2QGA-B nrPDB Length = 465 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 46/199 (23%), Positives = 77/199 (38%), Gaps = 11/199 (5%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 C +N + T + + + +IP L + L+ + E+ H+ + RTH Q A+ Sbjct: 120 CTSEDINNVAYATCLKAC----LNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPAS 175 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVK-IAEQISK 277 T G+E + + ++ + + + F G + +K V I + K Sbjct: 176 STTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKK 235 Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337 L + + + HD I E L +L + DI S +L + Sbjct: 236 HFNLTYSIYCTQIQ---DHDYICELCDGLARANGTLIDLCVDIWLYISN---NLLKLKVK 289 Query: 338 ENEPGSSIMPGKVNPTQNE 356 E E GSS MP KVNP E Sbjct: 290 EKEVGSSTMPHKVNPIDFE 308 >1YIS-A nrPDB Length = 478 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 48/192 (25%), Positives = 83/192 (43%), Gaps = 16/192 (8%) Query: 195 ALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLA-QG 253 A K+KE +V +GRTH Q A+ +T+G+ + Q++ Q ++ + F +G Sbjct: 140 AFSLKNKE---VVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGIKG 196 Query: 254 GTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALA---AHDAIVECSGALNTLA 310 T T D E + E K N+F + + +L+ L Sbjct: 197 ATGTQDSFLTLFAGDESKVEALD-ELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLG 255 Query: 311 CSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEALTQVCVQVMGN 368 + K+ DIR L + + EL+ P +++ GSS MP K NP ++E + +++ Sbjct: 256 AAAKKVCTDIRVLQA-----FGELLEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINA 310 Query: 369 -NAAITFAGSQG 379 A+T QG Sbjct: 311 PQEALTILADQG 322 >1DOF-A nrPDB Length = 403 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 57/232 (24%), Positives = 105/232 (45%), Gaps = 36/232 (15%) Query: 143 ILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIP---ELTNLKNALEAK 199 +L K G + VH +SND T A +L I+ L + + + L + Sbjct: 80 LLEQKSGCRYVH------YGATSNDIIDT----AWALLIRRALAAVKEKARAVGDQLASM 129 Query: 200 SKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGT 259 ++++ + +GRTH Q A P+TLG +F+ Y ++ +++A + + + A+ G AVGT Sbjct: 130 ARKYKTLEMVGRTHGQWAEPITLGFKFANYYYELYIACRQLALAEEFIR--AKIGGAVGT 187 Query: 260 GLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQD 319 + + +++ ++++ GL + +A ++ + AL +A ++A + Sbjct: 188 -MASWGELGLEVRRRVAERLGLPHHVITTQ---VAPRESFAVLASALALMAAVFERLAVE 243 Query: 320 IRYLGSGPRCGYHELMLPE------NEPGSSIMPGKVNPTQNEALTQVCVQV 365 IR EL PE GSS MP K NPT +E + + V Sbjct: 244 IR-----------ELSRPEIGEVVEGGGGSSAMPHKANPTASERIVSLARYV 284 >5VKW-A nrPDB Length = 482 Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust. Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 11/182 (6%) Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244 LIP+L N+ + L + E+ + +G TH Q A T+G+ + ++Q++ ++ + + Sbjct: 128 LIPKLVNVIDRLSKFALEYKDLPVLGWTHFQPAQLTTVGKRATLWLQELLWDLRNMVRAR 187 Query: 245 KTLSFLAQGGTAVGTGLNTKPGF--DVKIAEQISKETG--LKFQTAPNKFEALAAHDAIV 300 + GT GT + F D E++ K L F + + Sbjct: 188 NDIGLRGVKGTT-GTQASFLSLFHGDHDKVEELDKRVVELLGFDIVYPVTGQTYSRKIDI 246 Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360 + L + + K A DIR L + E +++ GSS M K NP + E + Sbjct: 247 DVLSPLASFGATAHKFATDIRLLANLKEI---EEPFEKSQIGSSAMAYKRNPMRCE---R 300 Query: 361 VC 362 VC Sbjct: 301 VC 302 >2FEL-A nrPDB Length = 359 Score = 35.8 bits (81), Expect = 0.041, Method: Compositional matrix adjust. Identities = 51/205 (24%), Positives = 82/205 (40%), Gaps = 25/205 (12%) Query: 164 SSNDTFPTVMHIAASLQIQNELIP-ELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTL 222 +S D T + + L++ E+I L +L + L + H G T +Q A +T+ Sbjct: 107 TSQDVIDTSLML--RLKMAAEIIATRLGHLIDTLGDLASRDGHKPLTGYTRMQAAIGITV 164 Query: 223 GQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGT--GLNTKPGFDVKIAEQISKETG 280 +G++ +E + R+ + F Q G A GT L G + ++K G Sbjct: 165 ADRAAGWIAPLERHLLRL-ETFAQNGFALQFGGAAGTLEKLGDNAG---AVRADLAKRLG 220 Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYL---GSGPRCGYHELMLP 337 L ++ + D I E + L+ + +L K QDI + GS R Sbjct: 221 L-----ADRPQWHNQRDGIAEFANLLSLVTGTLGKFGQDIALMAEIGSEIRL-------- 267 Query: 338 ENEPGSSIMPGKVNPTQNEALTQVC 362 GSS MP K NP E L + Sbjct: 268 SGGGGSSAMPHKQNPVNAETLVTLA 292 >6IG5-A nrPDB Length = 470 Score = 35.0 bits (79), Expect = 0.076, Method: Compositional matrix adjust. Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 11/164 (6%) Query: 210 GRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTKPGFD 268 G+THLQ A P+ L + + + R+ K + G G G+ L P Sbjct: 158 GKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDP--- 214 Query: 269 VKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPR 328 + I+ + G A N +A AA D E + +A L ++A+DI + S Sbjct: 215 ----DAIAADLGFS-AAADNSVDATAARDFAAEAAFVFAMIAVDLSRLAEDI-IVWSSTE 268 Query: 329 CGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI 372 GY L GSSIMP K NP E +++GN A + Sbjct: 269 FGYVTLH-DSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGL 311 >1H2B-A nrPDB Length = 359 Score = 31.6 bits (70), Expect = 0.73, Method: Compositional matrix adjust. Identities = 65/286 (22%), Positives = 103/286 (36%), Gaps = 80/286 (27%) Query: 205 HIVKIGRTH--LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLA-QGGTAVGT-- 259 H+V+ G H LQ P TLG E GY+++V G++ + + A GT + Sbjct: 59 HLVQ-GMWHELLQPKLPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRA 117 Query: 260 ------------GLNTKPGFD----------VKIAEQISKETGLKFQTAPNKFEALAAHD 297 GLN GF +K+ + IS+E + AP + A+ Sbjct: 118 GEDMHCENLEFPGLNIDGGFAEFMRTSHRSVIKLPKDISREK--LVEMAPLADAGITAYR 175 Query: 298 AIVECS--------------GALNTLACSLFK-------IAQDIRYLGSGPRCGYHELML 336 A+ + + G L +A L K IA D++ +L L Sbjct: 176 AVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVK---------EEKLKL 226 Query: 337 PENEPGSSIMPGKVNPTQNEALTQVCVQVM------GNNAAITFAGSQGQFE-----LNV 385 E ++ + +P + QVM G N A+ F GSQ + L Sbjct: 227 AERLGADHVVDARRDPVK---------QVMELTRGRGVNVAMDFVGSQATVDYTPYLLGR 277 Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSL 431 ++I +R T S V + N +HEL+T +L Sbjct: 278 MGRLIIVGYGGELRFPTIRVISSEVSFEGSLVGNYVELHELVTLAL 323 >6GZH-B nrPDB Length = 726 Score = 31.6 bits (70), Expect = 0.75, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRT--HLQDATPLTLGQEFSGYVQQVENGIQRV 240 N + P L +E + K+ +H++K+ T H Q++ P T + Y+QQV++ + Sbjct: 81 NSVAPAALFLAAKVEGQPKKLEHVIKVAHTCLHPQESLPDTRSE---AYLQQVQDLVILE 137 Query: 241 AHSLKTLSF 249 + L+TL F Sbjct: 138 SIILQTLGF 146 >3MIA-B nrPDB Length = 266 Score = 31.6 bits (70), Expect = 0.89, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRT--HLQDATPLTLGQEFSGYVQQVENGIQRV 240 N + P L +E + K+ +H++K+ T H Q++ P T + Y+QQV++ + Sbjct: 81 NSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSE---AYLQQVQDLVILE 137 Query: 241 AHSLKTLSF 249 + L+TL F Sbjct: 138 SIILQTLGF 146 >2PK2-A nrPDB Length = 358 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%) Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRT--HLQDATPLTLGQEFSGYVQQVENGIQRV 240 N + P L +E + K+ +H++K+ T H Q++ P T + Y+QQV++ + Sbjct: 81 NSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSE---AYLQQVQDLVILE 137 Query: 241 AHSLKTLSF 249 + L+TL F Sbjct: 138 SIILQTLGF 146 >4UEJ-A nrPDB Length = 346 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 11/19 (57%), Positives = 15/19 (78%) Query: 219 PLTLGQEFSGYVQQVENGI 237 P+TLG EFSGY+ V +G+ Sbjct: 54 PITLGHEFSGYIDAVGSGV 72 >5TUJ-C nrPDB Length = 235 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/55 (27%), Positives = 28/55 (50%), Gaps = 11/55 (20%) Query: 250 LAQGGTAVGTGLNTKP-----------GFDVKIAEQISKETGLKFQTAPNKFEAL 293 + +G VGT + KP GFD+ +A+ ++KE G+K + P ++ + Sbjct: 9 MKRGTLRVGTDADYKPFSFKDKNGQYTGFDIDLAKALAKELGVKVEFVPTTWDGI 63 >1A6R-A nrPDB Length = 471 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%) Query: 355 NEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVE 414 NE L+++ V+ + NN A+ F +F ++ VM L N Y + + Sbjct: 321 NETLSKLVVKRLQNNKAVFFGSHTPKF-MDKKTGVMDIELWN---------YPAIGYNLP 370 Query: 415 GIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALE-LGVLTEK 473 KA+ R HE L ML+T + D SK+ + K+S + L V+T+K Sbjct: 371 QQKASRIRYHESLMTHAMLITGCH----VDETSKLPLRYRVENSWGKDSGKDGLYVMTQK 426 Query: 474 EFDEW 478 F+E+ Sbjct: 427 YFEEY 431 >6G3D-A nrPDB Length = 508 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 45/178 (25%), Positives = 65/178 (36%), Gaps = 29/178 (16%) Query: 201 KEFDHI--VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV- 257 K DH+ V + T ++A P+TLG + + + R ++ G A Sbjct: 145 KAADHLDTVMVVYTQRKEAQPITLGHYLMAISENLAKNLDRYRELYARINLCPLGAAATA 204 Query: 258 GTG--LNTKP-----GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLA 310 GTG LN GFD GL N E +A D + E + Sbjct: 205 GTGWPLNRDRTSALLGFD-----------GLVV----NSIEGVAGWDHVAEHAFVNAVFL 249 Query: 311 CSLFKIAQDIRYLGSGPRCGYHELMLPENEPG-SSIMPGKVNPTQNEALTQVCVQVMG 367 L ++A +I+ + Y L + G SSIMP K NP E + MG Sbjct: 250 SGLSRLASEIQLWSTDE---YQVAELDASFAGTSSIMPQKKNPDSLERSRKAAFAAMG 304 >1AOS-A nrPDB Length = 464 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 68/298 (22%), Positives = 113/298 (37%), Gaps = 40/298 (13%) Query: 75 GVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANE 134 G+L K A +++ L GLD + A+E A G F+ S + ANE Sbjct: 53 GLLTK--AEMDQILHGLD--------KVAEEWAQG---------TFKLNSNDEDIHTANE 93 Query: 135 VISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKN 194 R E++G G ++H +S ND T + + Q + L L L Sbjct: 94 ---RRLKELIGATAG--KLHTG------RSRNDQVVTDLRLWMR-QTCSTLSGLLWELIR 141 Query: 195 ALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGG 254 + +++ ++ G THLQ A P+ + + +R+ K ++ L G Sbjct: 142 TMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGS 201 Query: 255 TAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLF 314 A+ G D E + E T N +A + D + E + L Sbjct: 202 GAIA---GNPLGVD---RELLRAELNFGAITL-NSMDATSERDFVAEFLFWRSLCMTHLS 254 Query: 315 KIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI 372 ++A+D+ L + +L GSS+MP K NP E + +V G A + Sbjct: 255 RMAEDL-ILYCTKEFSFVQLS-DAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGL 310 >5L43-A nrPDB Length = 683 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 6/48 (12%) Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKI 209 +QSS+DT PTV +IQ ++IP+LT +A+ F I +I Sbjct: 96 NQSSSDTNPTVQ------EIQKQIIPKLTQHGDAIHLNRPLFARIKQI 137 >1B65-A nrPDB Length = 375 Score = 29.3 bits (64), Expect = 4.4, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 9/85 (10%) Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266 V +G+ H++D TP + QE + + + + H LK L+ A ++G G N PG Sbjct: 230 VPVGQ-HMRDGTPQSQLQERGSIIVVLATDLPLMPHQLKRLARRA----SIGIGRNGTPG 284 Query: 267 ----FDVKIAEQISKETGLKFQTAP 287 D+ IA + + ++ ++AP Sbjct: 285 GNNSGDIFIAFSTANQRPMQHRSAP 309 >4JBT-A nrPDB Length = 410 Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 6/105 (5%) Query: 340 EPGSSIMPGKVNPTQNEA-LTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSI 398 EPG + + T E LT+ +V+GN A+ AG + L + + + + Sbjct: 210 EPGDDLTSALIYATDGETPLTEE--EVIGNLQALVAAGHETTVSLILTAVRALLSHPEQL 267 Query: 399 RLITDAAYSFRVHCVEGIKANEPRIHELL---TKSLMLVTALNPK 440 RL+ D + E ++ + P IH L+ T+ + L A+ P+ Sbjct: 268 RLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPR 312 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1YFM-A nrPDB 739 0.0 5UPP-A nrPDB 630 0.0 6N1M-A nrPDB 609 e-175 4HGV-A nrPDB 607 e-174 1VDK-A nrPDB 603 e-173 3GTD-A nrPDB 602 e-172 3TV2-A nrPDB 597 e-171 1FUP-A nrPDB 595 e-170 3R6Q-A nrPDB 561 e-160 4ADL-A nrPDB 550 e-157 3RD8-A nrPDB 539 e-153 3QBP-A nrPDB 536 e-152 3RRP-A nrPDB 522 e-148 1JSW-A nrPDB 509 e-144 3OCE-A nrPDB 503 e-142 1RE5-A nrPDB 268 4e-72 2X75-A nrPDB 260 1e-69 1Q5N-A nrPDB 246 1e-65 1TJ7-A nrPDB 243 1e-64 2PFM-A nrPDB 242 3e-64 1F1O-A nrPDB 237 1e-62 5EYT-A nrPDB 236 2e-62 1C3C-A nrPDB 221 7e-58 2J91-A nrPDB 220 1e-57 3C8T-A nrPDB 213 1e-55 1TJU-A nrPDB 213 2e-55 5V4L-A nrPDB 211 4e-55 2E9F-A nrPDB 209 2e-54 1I0A-A nrPDB 201 5e-52 5XNZ-A nrPDB 199 2e-51 4EFC-A nrPDB 184 6e-47 2QGA-B nrPDB 184 8e-47 3BHG-A nrPDB 181 7e-46 4MX2-A nrPDB 177 1e-44 4EEI-A nrPDB 174 8e-44 1YIS-A nrPDB 174 9e-44 2PTS-A nrPDB 171 4e-43 4NSL-A nrPDB 171 7e-43 5E3V-A nrPDB 167 7e-42 Sequences not found previously or not previously below threshold: 1AOS-A nrPDB 196 1e-50 5VKW-A nrPDB 190 1e-48 6IG5-A nrPDB 142 4e-34 1DOF-A nrPDB 131 7e-31 4NLE-A nrPDB 129 2e-30 2FEL-A nrPDB 122 5e-28 6G3D-A nrPDB 110 1e-24 1GFN-A nrPDB 35 0.056 1H2B-A nrPDB 33 0.39 4P1M-A nrPDB 30 2.5 5M3L-D nrPDB 29 3.5 4V93-B0 nrPDB 29 3.5 >1YFM-A nrPDB Length = 488 Score = 739 bits (1907), Expect = 0.0, Method: Composition-based stats. Identities = 487/488 (99%), Positives = 488/488 (100%) Query: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG Sbjct: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60 Query: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF Sbjct: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120 Query: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ Sbjct: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180 Query: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV Sbjct: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240 Query: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIV 300 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPN+FEALAAHDAIV Sbjct: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNRFEALAAHDAIV 300 Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ Sbjct: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360 Query: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE Sbjct: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420 Query: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV Sbjct: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480 Query: 481 PEHMLGPK 488 PEHMLGPK Sbjct: 481 PEHMLGPK 488 >5UPP-A nrPDB Length = 466 Score = 630 bits (1624), Expect = 0.0, Method: Composition-based stats. Identities = 313/467 (67%), Positives = 376/467 (80%), Gaps = 2/467 (0%) Query: 23 RMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAA 82 +SFR E D FGE+ VP DKY+GAQT RS NFKIGG ERMP P++ AFG+LK++AA Sbjct: 1 ASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAA 60 Query: 83 IVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIE 142 VN+ G LDPKI+ AI +AADEVA GKL+DHFPLVV+QTGSGTQ+NMN NEVISNRAIE Sbjct: 61 EVNQDYG-LDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIE 119 Query: 143 ILGGKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201 +LGG++GSK VHPN+H N+SQSSNDTFPT MHIAA++++ L+P L L +AL+AKSK Sbjct: 120 MLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSK 179 Query: 202 EFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGL 261 EF I+KIGRTH QDA PLTLGQEFSGYVQQV+ + R+ ++ + LA GGTAVGTGL Sbjct: 180 EFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGL 239 Query: 262 NTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIR 321 NT+ GF K+A +++ TGL F TAPNKFEALAAHDA+VE SGA+NT ACSL KIA DIR Sbjct: 240 NTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIR 299 Query: 322 YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQF 381 +LGSGPR G EL+LPENEPGSSIMPGKVNPTQ EA+T V QVMGN+ A+T GS G F Sbjct: 300 FLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHF 359 Query: 382 ELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI 441 ELNVFKP+MI N+L+S RL+ DA+ SF +CV GI+AN RI++L+ +SLMLVTALNP I Sbjct: 360 ELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHI 419 Query: 442 GYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488 GYD A+K+AK AHK G TLKE+A+ELG LT ++FDEWV P+ MLGPK Sbjct: 420 GYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK 466 >6N1M-A nrPDB Length = 472 Score = 609 bits (1571), Expect = e-175, Method: Composition-based stats. Identities = 280/464 (60%), Positives = 350/464 (75%), Gaps = 3/464 (0%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85 + R ETD+ GEI VP+DKYWGAQT+RS +F IG ++ MP + HAFG+LKK+AA+ N Sbjct: 10 AKTRVETDSMGEIEVPSDKYWGAQTERSLHHFNIG--KDIMPREVTHAFGILKKAAALTN 67 Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145 LG L + I QAA+EV+ G LD+HFPL V+QTGSGTQSNMNANEVISNRAIE+ G Sbjct: 68 LELGKLPKDKADLIVQAAEEVSKGLLDEHFPLHVWQTGSGTQSNMNANEVISNRAIELAG 127 Query: 146 GKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204 G +GSK +HPN+H N SQSSNDTFPT MHIAA++ +L+P + NL++ AK F Sbjct: 128 GTLGSKSPIHPNDHVNMSQSSNDTFPTAMHIAAAIAFNEKLLPAVRNLRHVFAAKMDAFK 187 Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264 +I+KIGRTHLQDA PLTLGQEFSGYV Q++ + R+ L L LA GGTAVGTGLNT Sbjct: 188 NIIKIGRTHLQDAVPLTLGQEFSGYVAQLDACVHRLEEVLPELYELAAGGTAVGTGLNTH 247 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 P F VK+AE I+K T L F TAPNKF ALA+H+ +V GA+ TLAC+L KIA DIR+L Sbjct: 248 PQFAVKVAEHIAKITKLPFVTAPNKFAALASHEPLVHAHGAMKTLACALMKIANDIRWLA 307 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384 SGPRCG EL++PENEPGSSIMPGKVNPTQ EA+T VC QV+GN+ A+ A SQG FELN Sbjct: 308 SGPRCGIGELIIPENEPGSSIMPGKVNPTQCEAMTMVCAQVLGNDTAVGIADSQGNFELN 367 Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444 VFKPV+I N+L+S+ L+ D+ +SF+ C EGI+ N+P I L SLMLVTALN IGYD Sbjct: 368 VFKPVIIFNVLHSLNLLADSCHSFQEFCAEGIEPNQPVIDYYLHHSLMLVTALNQHIGYD 427 Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488 A+K+AK AH I+L+E+A++LG+LT ++F E+V PE M+ P+ Sbjct: 428 KAAKIAKTAHHDNISLQEAAVKLGILTAEQFAEFVKPEKMISPE 471 >4HGV-A nrPDB Length = 495 Score = 607 bits (1566), Expect = e-174, Method: Composition-based stats. Identities = 299/463 (64%), Positives = 358/463 (77%), Gaps = 3/463 (0%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85 +S RTETD FG I V +D+YWGAQ QRS NFKIG E+ PL +V A G++K++AA N Sbjct: 34 TSTRTETDTFGPIEVASDRYWGAQAQRSLGNFKIG--WEKQPLAIVRALGIVKQAAARAN 91 Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145 +LG LDP I AI +AA EV GKLD+HFPLVV+QTGSGTQSNMNANEV+SNRAIE+LG Sbjct: 92 MALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLG 151 Query: 146 GKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204 G +GSK+ VHPN+H N SQSSNDT+PT MHIA + ++ ++L+P L +L ALE K K FD Sbjct: 152 GVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFD 211 Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264 HI+KIGRTH QDATPLTLGQEFSGY QV + I+R+ +L L LAQGGTAVGTGLN Sbjct: 212 HIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAP 271 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 GF K+AE+I+ TG+ F +APNKFEALAAHD++V GA+N A +LFKIA DIR+LG Sbjct: 272 VGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLG 331 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384 SGPR G EL LPENEPGSSIMPGKVNPTQ EALTQVCVQV GN+AA+TFAGSQG FELN Sbjct: 332 SGPRSGLGELSLPENEPGSSIMPGKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELN 391 Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444 V+ P+M N L S++L+ DAA SF +CV GI+A E I L +SLMLVTAL PKIGYD Sbjct: 392 VYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYD 451 Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 A+K+AK AHK G TL+E A+ G +T++EFD V PE M+GP Sbjct: 452 NAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGP 494 >1VDK-A nrPDB Length = 466 Score = 603 bits (1554), Expect = e-173, Method: Composition-based stats. Identities = 262/461 (56%), Positives = 324/461 (70%) Query: 27 SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNE 86 +R E D GE+ VPADKYWGAQTQRS +NF+IG R RMPL ++ A+G+LKK+AA N Sbjct: 2 EYRIERDTMGEVRVPADKYWGAQTQRSLENFRIGTDRFRMPLEIIRAYGMLKKAAARANL 61 Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146 LG L +I+KAI QAA+EV GK DDHFPLVVFQTGSGTQ+NMN NEVI+NRA EILG Sbjct: 62 ELGELPEEIAKAIIQAAEEVVQGKWDDHFPLVVFQTGSGTQTNMNVNEVIANRASEILGK 121 Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206 +GSK HPN+H N+ QSSNDTFPT M++A +L + L P + L AK++ FD I Sbjct: 122 PLGSKYAHPNDHVNRGQSSNDTFPTAMYVAVALALHQRLYPAVEGLIRTFTAKAQAFDQI 181 Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266 VK+GRTHL DA P+TLGQE + Q++ + V K L LA GGTAVGTGLN P Sbjct: 182 VKVGRTHLMDAVPITLGQEIGSWAAQLKTTLAAVKEMEKGLYNLAIGGTAVGTGLNAHPR 241 Query: 267 FDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSG 326 F +A+ +++ETGL F+ A N+F ALAAHD +V GA+ TLA +L KI D+R+L SG Sbjct: 242 FGELVAKYLAEETGLPFRVAENRFAALAAHDELVNVMGAIRTLAGALMKIGNDVRWLASG 301 Query: 327 PRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVF 386 P G E+ +P NEPGSSIMPGKVNPTQ EALT V V+V GN+ + FAGSQG F+LNV+ Sbjct: 302 PYAGIGEITIPANEPGSSIMPGKVNPTQVEALTMVVVRVYGNDHTVAFAGSQGNFQLNVY 361 Query: 387 KPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAA 446 KPVM + L SI L+ DA SF H +GI+ N RI E L K+ ML TALN IGYD A Sbjct: 362 KPVMAYSTLESINLLADAVASFDAHLAQGIEPNLERIEEYLQKNPMLATALNKAIGYDKA 421 Query: 447 SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 +++ K A K+ TLK++ALELG LTE+EFD VVP + P Sbjct: 422 AEIVKKALKEKKTLKQAALELGYLTEEEFDRIVVPMRLAKP 462 >3GTD-A nrPDB Length = 482 Score = 602 bits (1551), Expect = e-172, Method: Composition-based stats. Identities = 281/460 (61%), Positives = 351/460 (76%), Gaps = 3/460 (0%) Query: 27 SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNE 86 ++R E+D+FGEI + YWGAQTQRS NFKI +++MP L+ A +LKK AA VN Sbjct: 24 NYRIESDSFGEIQIEEKFYWGAQTQRSLNNFKIS--KQKMPKILIRALAILKKCAAQVNY 81 Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146 G L+ KI+ +I +A D + +G+ +D+FPLVV+QTGSGTQ+NMN NEVI++ A E L G Sbjct: 82 EFGDLEYKIATSIDKAIDRILAGEFEDNFPLVVWQTGSGTQTNMNMNEVIASIANEELTG 141 Query: 147 KIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205 K G K VHPN+H N+ QSSND+FPT MHIA L + +LIP L NL L+ KSK++D Sbjct: 142 KKGGKFPVHPNDHVNKGQSSNDSFPTAMHIATVLATKQQLIPALNNLLTYLQDKSKDWDK 201 Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKP 265 I+KIGRTHLQDATPLTL QEFSGY+ Q+E ++R+ +LK + LAQGGTAVGTG+N+K Sbjct: 202 IIKIGRTHLQDATPLTLKQEFSGYITQIEYALERIEDALKKVYLLAQGGTAVGTGINSKI 261 Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325 GFD+K A+++++ T F+TAPNKFE+LAAHDA+VE SG LNT+A SL KIA DIR LGS Sbjct: 262 GFDIKFAQKVAEFTQQPFKTAPNKFESLAAHDALVEFSGTLNTIAVSLMKIANDIRLLGS 321 Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385 GPRCG EL LPENEPGSSIMPGKVNPTQ EALT VC QVMGN+ +T AGS G ELNV Sbjct: 322 GPRCGLGELHLPENEPGSSIMPGKVNPTQVEALTMVCTQVMGNHVTVTIAGSNGHLELNV 381 Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445 FKPV+I N+L SI L++D+ SF HCV+G++ N RI+ L KSLMLVT LNP IGYD Sbjct: 382 FKPVIIYNILQSIELLSDSVNSFVTHCVKGLEPNIARINTLRDKSLMLVTVLNPHIGYDN 441 Query: 446 ASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485 A+K+AK AHK GITLKE+A +L L+E+EFD+ VVPE M+ Sbjct: 442 AAKIAKEAHKYGITLKEAAKKLNFLSEEEFDKIVVPEKMI 481 >3TV2-A nrPDB Length = 459 Score = 597 bits (1539), Expect = e-171, Method: Composition-based stats. Identities = 275/459 (59%), Positives = 336/459 (73%), Gaps = 3/459 (0%) Query: 29 RTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESL 88 R E D FGEI VPA + WGAQTQRS QNFKI E+ L+HA ++K++AA VN L Sbjct: 1 RMERDTFGEIAVPAARLWGAQTQRSLQNFKIS--TEKQSPELIHALALIKRAAAAVNLEL 58 Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148 G L + AI AADE+ +G+ D FPL V+QTGSGTQ+NMN NEVI+NRA E+LGG+ Sbjct: 59 GVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGER 118 Query: 149 G-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207 G S+ VHPN+ N+ QSSND FPT MHIAA+ I + L+P L L+ L+AK+ F IV Sbjct: 119 GESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIV 178 Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267 KIGRTHLQDATPLTLGQEFSGYV Q++ GI+ V +L L LAQGGTAVGTGLN P F Sbjct: 179 KIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKF 238 Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327 +A +I + TGL F +APNKFE +AA DA+V GAL T+A SL KIA DIR+L SGP Sbjct: 239 AAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGP 298 Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387 RCG EL +PENEPGSSIMPGKVNPTQ+EA+T +C QV GN+ A+ F G+ G FELNVF+ Sbjct: 299 RCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFR 358 Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447 P++ N+L S+RL+ D A F HC GI+ N RI LL +SLMLVTALNP IGYD A+ Sbjct: 359 PMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAA 418 Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486 ++AK AHK+G TLK +AL LG +T+ +FDEWV PEHM+G Sbjct: 419 QIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG 457 >1FUP-A nrPDB Length = 472 Score = 595 bits (1534), Expect = e-170, Method: Composition-based stats. Identities = 270/462 (58%), Positives = 344/462 (74%), Gaps = 3/462 (0%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85 ++ R+E D+ G I VPADK WGAQTQRS ++F+I E+MP L+HA + K++AA VN Sbjct: 2 NTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRIS--TEKMPTSLIHALALTKRAAAKVN 59 Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145 E LG L + + AI+QAADEV +G+ DD FPL ++QTGSGTQSNMN NEV++NRA E+LG Sbjct: 60 EDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLG 119 Query: 146 GKIG-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204 G G ++VHPN+ N+SQSSND FPT MH+AA L ++ +LIP+L L L KS+ F Sbjct: 120 GVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFA 179 Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264 IVKIGRTHLQDATPLTLGQE SG+V +E+ ++ + +SL ++ LA GGTAVGTGLNT Sbjct: 180 DIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTH 239 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 P + ++A++++ T F TAPNKFEALA DA+V+ GAL LA SL KIA D+R+L Sbjct: 240 PEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLA 299 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384 SGPRCG E+ +PENEPGSSIMPGKVNPTQ EALT +C QVMGN+ AI G+ G FELN Sbjct: 300 SGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELN 359 Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444 VF+P++I N L S+RL+ D SF HC GI+ N RI++LL +SLMLVTALN IGYD Sbjct: 360 VFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYD 419 Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486 A+++AK AHK+G+TLK +AL LG L+E EFD WV PE M+G Sbjct: 420 KAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMVG 461 >3R6Q-A nrPDB Length = 468 Score = 561 bits (1446), Expect = e-160, Method: Composition-based stats. Identities = 203/465 (43%), Positives = 297/465 (63%), Gaps = 4/465 (0%) Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83 MN+ R E D GE +P D Y+G QT R+ +NF I G R+ L+ + G++KKSAA+ Sbjct: 1 MNTDVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGY--RIHPELIKSLGIVKKSAAL 58 Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143 N +G LD ++ + I +AADEV GK +D F + Q G+GT NMNANEVI+NRA+E+ Sbjct: 59 ANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALEL 118 Query: 144 LGGKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKE 202 +G + G+ ++ PN+H N SQS+ND FPT HIA L + N+LI ++ K+ E Sbjct: 119 MGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAV-LSLLNQLIETTKYMQQEFMKKADE 177 Query: 203 FDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLN 262 F ++K+GRTHLQDA P+ LGQEF Y + + I+R+A++ L + G TAVGTGLN Sbjct: 178 FAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLN 237 Query: 263 TKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 P + + E ++K +G ++A + +A D E S AL ++ KIA D+R Sbjct: 238 ADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRL 297 Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 + SGPR G E++LP +PGSSIMPGKVNP E + QV QV GN+ IT A GQFE Sbjct: 298 MASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFE 357 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 LNV +PV+ NL+ SI ++T+ SF +C++GIKANE R+ E + KS+ ++TA+NP +G Sbjct: 358 LNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEERMKEYVEKSIGIITAINPHVG 417 Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 Y+ A+K+A+ A+ G +++E ++ GVLTE++ +E + P M+ P Sbjct: 418 YETAAKLAREAYLTGESIRELCIKYGVLTEEQLNEILNPYEMIHP 462 >4ADL-A nrPDB Length = 495 Score = 550 bits (1418), Expect = e-157, Method: Composition-based stats. Identities = 227/484 (46%), Positives = 306/484 (63%), Gaps = 15/484 (3%) Query: 11 TFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLP 69 + K + + + ++++R E D GE+ VPA W AQTQR+ +NF I G ER Sbjct: 15 SLYKKAGSMAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQ-- 72 Query: 70 LVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSN 129 + A G+LK + A VN LG L P+ + AI AA E+A G+ DD FP+ VFQTGSGT SN Sbjct: 73 -IRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSN 131 Query: 130 MNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPEL 189 MN NEVI++ A + G +HPN+ N SQSSNDTFPT HIAA+ LIP L Sbjct: 132 MNTNEVIASIAAK------GGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPAL 185 Query: 190 TNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSF 249 L +AL AK+ ++ +VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV L L Sbjct: 186 QQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGE 245 Query: 250 LAQGGTAVGTGLNTKPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNT 308 LA GGTAVGTGLN F V++ + +TGL + +TA N FEA AA D +VE SGAL T Sbjct: 246 LAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRT 305 Query: 309 LACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGN 368 +A SL KIA DIR++GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN Sbjct: 306 IAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGN 365 Query: 369 NAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLT 428 +AAI + G+ G FELNV+ P+M N+L S +L+T+ + F C+ G+ AN + L Sbjct: 366 DAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAE 425 Query: 429 KSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHM 484 S +VT LN IGY+ A+ VAK A K+ T++++ ++ G++ + ++ D + M Sbjct: 426 SSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAM 485 Query: 485 LGPK 488 + Sbjct: 486 AKAE 489 >3RD8-A nrPDB Length = 489 Score = 539 bits (1388), Expect = e-153, Method: Composition-based stats. Identities = 234/466 (50%), Positives = 302/466 (64%), Gaps = 15/466 (3%) Query: 25 NSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG-GARERMPLPLVHAFGVLKKSAAI 83 + +R E D GE+ VP D W AQTQR+ +NF I ER + A G+LK + A Sbjct: 26 DVEYRIEHDTMGEVRVPKDALWRAQTQRAVENFPISFRGLERTQ---IRALGLLKAACAQ 82 Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143 VN+ LG LDP+ + AI AA E+A GK DD FP+ VFQTGSGT SNMN NEVI++ A Sbjct: 83 VNKDLGLLDPEKADAIIAAAGEIAEGKHDDQFPIDVFQTGSGTSSNMNTNEVIASIAA-- 140 Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEF 203 VHPN+H N SQSSNDTFPT HIAA+ LIP L L +L AK+K++ Sbjct: 141 ----ANGVTVHPNDHVNMSQSSNDTFPTATHIAATEAAVRHLIPALEVLHASLAAKAKQW 196 Query: 204 DHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNT 263 +VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L LA GGTAVGTGLN Sbjct: 197 RTVVKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELAIGGTAVGTGLNA 256 Query: 264 KPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 GF K+ E + ETGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR+ Sbjct: 257 PEGFGAKVVEVLVNETGLAELRTAVDSFEAQAARDGLVEASGALRTIAVSLTKIANDIRW 316 Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 +GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAI F G+ G FE Sbjct: 317 MGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVACQVVGNDAAIAFGGASGAFE 376 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 LNV+ P+M NLL S L+++ + F C++G+ ANE R+ EL S +VT LN IG Sbjct: 377 LNVYIPMMARNLLESFTLLSNVSRLFAERCIDGLVANEERLRELAESSPSIVTPLNSAIG 436 Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHM 484 Y+ A+KVAK A + T++++ ++ G++ + +E D + M Sbjct: 437 YEEAAKVAKQALAEKKTIRQTVIDRGLIGDKLSLEELDRRLDVLAM 482 >3QBP-A nrPDB Length = 478 Score = 536 bits (1380), Expect = e-152, Method: Composition-based stats. Identities = 229/466 (49%), Positives = 300/466 (64%), Gaps = 15/466 (3%) Query: 25 NSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAI 83 ++ +R E D GE+ VPA W AQTQR+ +NF I G ER + A G+LK + A Sbjct: 16 DTEYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERAQ---IRALGLLKGACAQ 72 Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143 VN LG L P+ ++AI AA E+A G+ DD FP+ VFQTGSGT SNMN NEVI++ A Sbjct: 73 VNMDLGLLAPEKAEAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIA--- 129 Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEF 203 VHPN+ N SQSSNDTFPT HIAA+ + LIP L L++AL K+ E+ Sbjct: 130 ---GANGVAVHPNDDVNMSQSSNDTFPTATHIAATEAAVSHLIPALEILQDALATKALEW 186 Query: 204 DHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNT 263 +VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV +L L LA GGTAVGTGLN Sbjct: 187 QSVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRATLPRLGELAIGGTAVGTGLNA 246 Query: 264 KPGFDVKIAEQISKETGLK-FQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 GF VK+ + +TGL +TA N FEA AA D +VE SGAL T+A SL KIA DIR+ Sbjct: 247 PEGFGVKVVSVLVSQTGLPQLRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRW 306 Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 +GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AA+ + G+ G FE Sbjct: 307 MGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAVAWGGANGAFE 366 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 LNV+ P+M N+L S L+T+ + F C+ G+ AN + EL S +VT LN IG Sbjct: 367 LNVYIPMMARNILESFTLLTNVSKLFAQRCIAGLTANAEHLRELAESSPSIVTPLNSAIG 426 Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHM 484 Y+ A+ VAK A K+ T++++ ++ G++ + +E D + M Sbjct: 427 YEEAAAVAKQALKERKTIRQTVIDRGLIGDKLSLEELDRRLDVLAM 472 >3RRP-A nrPDB Length = 471 Score = 522 bits (1344), Expect = e-148, Method: Composition-based stats. Identities = 231/467 (49%), Positives = 299/467 (64%), Gaps = 13/467 (2%) Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAIVNE 86 +R E D GE+ VPA+ W AQTQR+ +NF I G ER + A G+LK + A VN+ Sbjct: 11 YRIEHDTMGEVRVPAEALWRAQTQRAVENFPISGRGLERTQ---IRALGLLKGACAQVNK 67 Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146 LG L + + AI AA E+A GK DD FP+ VFQTGSGT SNMNANEVI++ A + Sbjct: 68 DLGLLAAEKADAIIAAAQEIADGKHDDQFPIDVFQTGSGTSSNMNANEVIASIAAQATPP 127 Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206 VHPN+ N SQSSNDTFPT H+AA+ +LIP L L+ AL K+K + + Sbjct: 128 V----VVHPNDDVNMSQSSNDTFPTATHLAATEAAVRDLIPALEYLQQALATKAKAWKTV 183 Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266 VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L L GGTAVGTGLN G Sbjct: 184 VKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELPIGGTAVGTGLNAPDG 243 Query: 267 FDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325 F K+ E + + TGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR++GS Sbjct: 244 FGAKVVEVLKQSTGLSELKTASDSFEAQAARDGLVEGSGALKTIAASLTKIANDIRWMGS 303 Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385 GP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAIT G G FELNV Sbjct: 304 GPLTGLGEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAITVGGLSGAFELNV 363 Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445 + PVM NLL S L+ + + F CV+G+ ANE + L S +VT LN IGY+ Sbjct: 364 YIPVMARNLLESFTLLANVSRLFVDKCVDGLVANEDHLRTLAESSPSIVTPLNSAIGYEE 423 Query: 446 ASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHMLGPK 488 A+ VAK A K+ T++++ ++ G++ + +E D+ + M K Sbjct: 424 AAAVAKEALKERKTIRQTVIDRGLIGDKLSIEELDKRLDVLAMAKVK 470 >1JSW-A nrPDB Length = 478 Score = 509 bits (1310), Expect = e-144, Method: Composition-based stats. Identities = 176/466 (37%), Positives = 269/466 (57%), Gaps = 3/466 (0%) Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83 M+++ R E D G VPAD Y+G T R+ +NF I + V ++KK+AA+ Sbjct: 1 MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAM 60 Query: 84 VNESLGGLDPKISKAIQQAADEVAS-GKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIE 142 N+ L + ++ AI A DEV + GK D FP+ V+Q G+GT NMN NEV++N +E Sbjct: 61 ANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLE 120 Query: 143 ILGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201 ++G + G Q ++PN+H N+ QS+ND +PT IA + +L+ + L+ E K+ Sbjct: 121 LMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLI-KLVDAINQLREGFERKAV 179 Query: 202 EFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGL 261 EF I+K+GRT LQDA P+TLGQEF + ++ ++ + + + L + G TA+GTGL Sbjct: 180 EFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGL 239 Query: 262 NTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIR 321 NT + +++++ TG A + EA + A V GAL LA + KI D+R Sbjct: 240 NTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLR 299 Query: 322 YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQF 381 L SGPR G +E+ LPE + GSSIMP KVNP E + QVC +V+GN+ +T A GQ Sbjct: 300 LLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQL 359 Query: 382 ELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI 441 +LNV +PV+ + S+ ++T+A Y+ C+ GI AN+ + S+ +VT LNP I Sbjct: 360 QLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFI 419 Query: 442 GYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 G+ V K + G +++E LE G+LTE E D+ ++++ P Sbjct: 420 GHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHP 465 >3OCE-A nrPDB Length = 474 Score = 503 bits (1294), Expect = e-142, Method: Composition-based stats. Identities = 190/463 (41%), Positives = 263/463 (56%), Gaps = 3/463 (0%) Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85 S R E D+ GE +P D Y+G QT R+ +NF + LV A ++KK+AA N Sbjct: 4 SMTRREQDSLGERDIPMDAYFGIQTLRAVENFSLSDVALNHIPALVRALAMVKKAAATAN 63 Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145 L L AI A D++ G L + F + VFQ G+GT SNMNANEVI+NRA+E LG Sbjct: 64 YKLRQLPEPKYAAIVAACDDIIDGLLMEQFVVDVFQGGAGTSSNMNANEVIANRALEHLG 123 Query: 146 GKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204 G Q +HPN+ N SQS+ND +PT + +A L QN++ L L A EAK +EF Sbjct: 124 RPRGDYQTIHPNDDVNMSQSTNDVYPTAVRLALLLS-QNQVQTALHRLIAAFEAKGREFA 182 Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264 ++KIGRT LQDA P+TLGQEF + + R+ + GGTA+GT +N Sbjct: 183 TVIKIGRTQLQDAVPITLGQEFEAFAATLREDTARLEEVAALFREVNLGGTAIGTRINAS 242 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 + + ++S+ +G++ + N EA A V SG L +A L KIA D+R L Sbjct: 243 HAYAEQAIVELSQISGIELKATGNLVEASWDTGAFVTFSGILRRIAVKLSKIANDLRLLS 302 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384 SGPR G E+ LP +PGSSIMPGKVNP E++ QVC QV+GN+ +T A GQ +LN Sbjct: 303 SGPRSGLGEIRLPAVQPGSSIMPGKVNPVIPESVNQVCYQVIGNDLTVTMAAESGQLQLN 362 Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444 F+P+++ N+L+S+RL+ A + CV+GI+AN R +S+ L TAL P +GY Sbjct: 363 AFEPLIVYNILSSMRLLGRAMTNLAERCVDGIEANVERCRAGAEESISLATALVPVVGYA 422 Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487 A+++AK A G T+ E A+ G L + P M P Sbjct: 423 RAAEIAKQALASGQTVMEVAISKG-LDASALTIMLDPLRMAFP 464 >1RE5-A nrPDB Length = 450 Score = 268 bits (685), Expect = 4e-72, Method: Composition-based stats. Identities = 92/416 (22%), Positives = 152/416 (36%), Gaps = 44/416 (10%) Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148 G + AI+ A + + T N V + LG I Sbjct: 43 GLVPHSAVAAIEAACQ-------AERYDTGALANAIATAGNSAIPLVKA------LGKVI 89 Query: 149 GSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVK 208 + + + +S D T + + + + + +L L + L ++ + Sbjct: 90 ATGVPEAERYVHLGATSQDAMDTGLVLQLRDAL-DLIEADLGKLADTLSQQALKHADTPL 148 Query: 209 IGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKT---LSFLAQGGTAVGTGLNTKP 265 +GRT LQ ATP+TLG + +G + + QR+ L F G+ G P Sbjct: 149 VGRTWLQHATPVTLGMKLAGVLGALTRHRQRLQELRPRLLVLQFGGASGSLAALGSKAMP 208 Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325 +AE ++++ L P + D +VE + L +A SL K +DI L Sbjct: 209 -----VAEALAEQLKLTLPEQPWHTQ----RDRLVEFASVLGLVAGSLGKFGRDISLLMQ 259 Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385 E P + GSS MP K NP L +V G + + FA + E ++ Sbjct: 260 TEAGEVFEPSAP-GKGGSSTMPHKRNPVGAAVLIGAATRVPGLLSTL-FAAMPQEHERSL 317 Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHEL--LTKSLMLVTA----LNP 439 L I + A EG++ + R+ LT+ L+L A L Sbjct: 318 GLWHAEWETLPDICCLVSGALRQAQVIAEGMEVDAARMRRNLDLTQGLVLAEAVSIVLAQ 377 Query: 440 KIGYDAA---------SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486 ++G D A VA+ H + + E + L+ +E D + P H LG Sbjct: 378 RLGRDRAHHLLEQCCQRAVAEQRHLRAVLGDEPQVS-AELSGEELDRLLDPAHYLG 432 >2X75-A nrPDB Length = 431 Score = 260 bits (663), Expect = 1e-69, Method: Composition-based stats. Identities = 76/346 (21%), Positives = 131/346 (37%), Gaps = 34/346 (9%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 + +S D T + Q + + +L + L K+K + + + +GRTH A Sbjct: 88 VHYGLTSTDVVDTALSF-VIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAE 146 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKE 278 P T G + + + +++ +QR + + G AVGT N P + + K Sbjct: 147 PTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSG-AVGTFANIPPEIESYVC----KH 201 Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPE 338 G+ + D L +A SL K A +IR L E + Sbjct: 202 LGIGTAPVSTQ---TLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEE-AFAK 257 Query: 339 NEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGS--QGQFELNVFKPVMIANLLN 396 + GSS MP K NP +E +T + + G IT A E ++ +L Sbjct: 258 GQKGSSAMPHKRNPIGSENITGISRVIRG---YITTAYENVPLWHERDISHSSAERIMLP 314 Query: 397 SIRLITDAAYSFRVHCV-------EGIKANEPRIHELLTKSLMLVTALNPKIGYDAA--- 446 + + D A + + V + ++ N + L+ +L+ +N + + A Sbjct: 315 DVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDK 374 Query: 447 -------SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485 S K ++ I ES VLT++E DE P+H L Sbjct: 375 VQPKAMISWETKTPFRELIEQDESIT--SVLTKEELDECFDPKHHL 418 >1Q5N-A nrPDB Length = 454 Score = 246 bits (628), Expect = 1e-65, Method: Composition-based stats. Identities = 97/435 (22%), Positives = 172/435 (39%), Gaps = 46/435 (10%) Query: 70 LVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSN 129 +V A L ++ A V G+ P+ + + Q A + A K+D T +G N Sbjct: 30 MVEAEVALAQAQAQV-----GVIPQSAATVIQRAAKTAIDKID----FDALATATGLAGN 80 Query: 130 MNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPEL 189 + V AI + ++ VH +S D T A LQ ++ L Sbjct: 81 IAIPFVKQLTAIVKDADEDAARYVHWGA------TSQDILDT----ACILQCRDALAIVQ 130 Query: 190 TNLKNALE---AKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKT 246 ++ E ++++ + H V +GRT LQ A P+TLG + + + + + R+ Sbjct: 131 NQVQQCYETALSQAQTYRHQVMMGRTWLQQALPITLGHKLARWASAFKRDLDRINAIKAR 190 Query: 247 LSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGAL 306 + +AQ G AVG+ + + + + E +K+ L QTA D IVE + L Sbjct: 191 V-LVAQLGGAVGSLASLQDQGSI-VVEAYAKQLKLG-QTACTWH---GERDRIVEIASVL 244 Query: 307 NTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVM 366 + ++ K+A+D + E + GSS MP K NP ++ +V Sbjct: 245 GIITGNVGKMARDWSLMMQTEIAEVFEPT-AKGRGGSSTMPHKRNPVAAASVLAAANRVP 303 Query: 367 GNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHEL 426 ++I + + E ++ L I +T A + ++G++ N +H+ Sbjct: 304 ALMSSI-YQSMVQEHERSLGAWHAEWLSLPEIFQLTAGALERTLDVLKGMEVNAENMHQN 362 Query: 427 LTKSLMLV------TALNPKIGYDAA---------SKVAKNAHKKGITLKESALELGVLT 471 + + L+ AL P +G A + VA+ H K I + + Sbjct: 363 IECTHGLIMAEAVMMALAPHMGRLNAHHVVEAACKTAVAEQKHLKDI-ISQVDEVKQYFN 421 Query: 472 EKEFDEWVVPEHMLG 486 + DE PE LG Sbjct: 422 PSQLDEIFKPESYLG 436 >1TJ7-A nrPDB Length = 457 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 75/326 (23%), Positives = 129/326 (39%), Gaps = 29/326 (8%) Query: 146 GKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205 GK+ K + +S ND T + + + +EL+ L++AL ++ Sbjct: 90 GKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTV-SELLTANRQLQSALVETAQNNQD 148 Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTK 264 V G THLQ A P+T YV+ + R+ +LK L G G GT Sbjct: 149 AVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEID 208 Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324 EQ++ G T N ++++ D ++E A L + A+D+ + Sbjct: 209 R-------EQLAGWLGFASAT-RNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFN 260 Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNA--AITFAGSQGQFE 382 +G G+ EL GSS+MP K NP E + C +V G +T G + Sbjct: 261 TG-EAGFVELS-DRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYN 318 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 ++ + L +++ D + ++GI+ PR E + G Sbjct: 319 KDMQEDK--EGLFDALDTWLDCLH-MAALVLDGIQVKRPRCQEAAQQ------------G 363 Query: 443 YDAASKVAKNAHKKGITLKESALELG 468 Y A+++A KG+ +E+ +G Sbjct: 364 YANATELADYLVAKGVPFREAHHIVG 389 >2PFM-A nrPDB Length = 444 Score = 242 bits (617), Expect = 3e-64, Method: Composition-based stats. Identities = 69/344 (20%), Positives = 131/344 (38%), Gaps = 30/344 (8%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 + +S D T + Q ++ +L N + L K+KE + + +GRTH A Sbjct: 99 VHYGLTSTDVVDTAL-SYILKQANEIILKDLENFVSILANKAKEHKYTIMMGRTHGVHAE 157 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKE 278 P T G + + ++++ ++R + T+ G AVGT N P + + E Sbjct: 158 PTTFGLKLGLWYEEMKRNVERFKQAANTVRVGKLSG-AVGTYANIDPFVEKYVCE----- 211 Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPE 338 L + AP + L D L +A S+ K+A +IR L E + Sbjct: 212 -NLGLEAAPISTQTL-QRDRHAHYMSTLALIATSIEKMAVEIRGLQKSETREVEE-AFAK 268 Query: 339 NEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSI 398 + GSS MP K NP +E +T + + G + E ++ +L Sbjct: 269 GQKGSSAMPHKRNPIGSENMTGLARVIRGYMMT-AYENVPLWHERDISHSSAERVILPDA 327 Query: 399 RLITDAAYSFRVHCVEGIKA-------NEPRIHELLTKSLMLVTALNPKIGYDAA----- 446 + + + + V+ + N R + L+ +++T ++ + + A Sbjct: 328 TIALNYMLNRFGNIVKNLTVYPENMKRNMTRTYGLIYSQRVMLTLIDKGMVREEAYDIVQ 387 Query: 447 -----SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485 + + K+ + E LT++E +E EH + Sbjct: 388 PKAMEAWETQVQFKELVEADERITSK--LTQEEINECFNYEHHM 429 >1F1O-A nrPDB Length = 431 Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats. Identities = 66/342 (19%), Positives = 129/342 (37%), Gaps = 26/342 (7%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 + +S D T + Q + L+ +L + ++ K+KE + V +GRTH A Sbjct: 88 VHYGLTSTDVVDTAL-SYLLKQANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAE 146 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKE 278 P T G + + + ++++ ++R + + G AVGT N P + + E++ Sbjct: 147 PTTFGLKLALWHEEMKRNLERFKQAKAGIEVGKISG-AVGTYANIDPFVEQYVCEKL--- 202 Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPE 338 + AP + L D + L +A S+ K A +IR L E + Sbjct: 203 ---GLKAAPISTQTL-QRDRHADYMATLALIATSIEKFAVEIRGLQKSETREVEE-FFAK 257 Query: 339 NEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSI 398 + GSS MP K NP +E +T + + G + E ++ +L Sbjct: 258 GQKGSSAMPHKRNPIGSENMTGMARVIRGYMMT-AYENVPLWHERDISHSSAERIILPDA 316 Query: 399 RLITDAAYSFRVHCVEGIKA-------NEPRIHELLTKSLMLVTALNPKI----GYDAAS 447 + + + + V+ + N R L+ +L+ ++ + YD Sbjct: 317 TIALNYMLNRFSNIVKNLTVFPENMKRNMDRTLGLIYSQRVLLALIDTGLTREEAYDTVQ 376 Query: 448 KVAKNAHKKGITLKESALE----LGVLTEKEFDEWVVPEHML 485 A A +K + +E L+ ++ + + L Sbjct: 377 PKAMEAWEKQVPFRELVEAEEKITSRLSPEKIADCFDYNYHL 418 >5EYT-A nrPDB Length = 497 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 73/324 (22%), Positives = 139/324 (42%), Gaps = 28/324 (8%) Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH 242 N L+P++ + L K+ ++ + RTHLQ A P T+G+ ++Q + ++ + Sbjct: 140 NILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLER 199 Query: 243 SLK-TLSFLAQGGTAVGTGLNTKPGFD------VKIAEQISKETGLKFQTAPNKFEALAA 295 T+ F G AVGT + F +K+ E ++K++G + Sbjct: 200 LKNHTIRFRGAKG-AVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVT--GQTYP 256 Query: 296 HDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPT 353 +E + AL+ + ++ KI DIR L S +HE+ P + GSS MP K NP Sbjct: 257 RKVDIEITNALSNIGATVHKICTDIRLLSS-----FHEVEEPFETKQIGSSAMPYKRNPI 311 Query: 354 QNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCV 413 ++E + +M + ++ S E ++ + +L L DA + + Sbjct: 312 RSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIA 371 Query: 414 EGIKANEPRIHELLTKS---LMLVTALNPKIGYDAAS-------KVAKNAHKKGITLKES 463 EG+ P + E S ++V + K+ + A+ ++ K++H+ +K Sbjct: 372 EGLIVY-PMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLK 430 Query: 464 ALELGVLTEKEFDEWVVPEHMLGP 487 L+ ++ + D + P H L P Sbjct: 431 GLKNSLMDKLLNDYYFAPIHSLLP 454 >1C3C-A nrPDB Length = 429 Score = 221 bits (562), Expect = 7e-58, Method: Composition-based stats. Identities = 77/426 (18%), Positives = 151/426 (35%), Gaps = 50/426 (11%) Query: 77 LKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVI 136 ++ + E LG + +++ I+ A K+D + E Sbjct: 25 VELAVTRAYEELGMIPKGVTERIRNNA------KIDVELFKKI--------------EEK 64 Query: 137 SNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNAL 196 +N + IGS + + +S+D T +A L+ L + L Sbjct: 65 TNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEA-GKILLESLKEFCDVL 123 Query: 197 EAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTA 256 + + H IGRTH A P + G + G+ +++ +QR+ +++ +S+ G A Sbjct: 124 WEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISG-A 182 Query: 257 VGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKI 316 VG N P + E+ GLK + + + D L +A + +I Sbjct: 183 VGNYANVPPE----VEEKALSYLGLKPEPVSTQ---VVPRDRHAFYLSTLAIVAAGIERI 235 Query: 317 AQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAG 376 A +IR+L E + + GSS MP K NP E LT + ++M + Sbjct: 236 AVEIRHLQRTEVLEVEEP-FRKGQRGSSAMPHKKNPITCERLTGLS-RMMRAYVDPSLEN 293 Query: 377 SQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRI-------HELLTK 429 E ++ + + + V +K NE R+ L+ Sbjct: 294 IALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFS 353 Query: 430 SLMLVTALNPKIGYDAA----------SKVAKNAHKKGITLKESALELGVLTEKEFDEWV 479 +L+ + + A + ++ + + E + ++T++E +E Sbjct: 354 QRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKK--LVTKEELEELF 411 Query: 480 VPEHML 485 + L Sbjct: 412 DISYYL 417 >2J91-A nrPDB Length = 503 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 68/324 (20%), Positives = 116/324 (35%), Gaps = 16/324 (4%) Query: 173 MHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQ 232 + + L+P+L + + L +KE + +G TH Q A T+G+ ++Q Sbjct: 141 TDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQD 200 Query: 233 VENGIQRVAHSLKTLSFLAQGGT--AVGTGLNTKPGFDVKIAEQISKETGLK--FQTAPN 288 + +Q + L F GT + L G D K+ EQ+ K K F+ A Sbjct: 201 LCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKV-EQLDKMVTEKAGFKRAFI 259 Query: 289 KFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPG 348 +E L +L S+ KI DIR L + E + + GSS MP Sbjct: 260 ITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEM---EEPFEKQQIGSSAMPY 316 Query: 349 KVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSF 408 K NP ++E + +M S FE + L L D + Sbjct: 317 KRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNT 376 Query: 409 RVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKK--------GITL 460 + EG+ I + + L + N + A ++ H+K + Sbjct: 377 LQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVV 436 Query: 461 KESALELGVLTEKEFDEWVVPEHM 484 K+ + ++ + D + P H Sbjct: 437 KQEGGDNDLIERIQVDAYFSPIHS 460 >3C8T-A nrPDB Length = 451 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 70/363 (19%), Positives = 131/363 (36%), Gaps = 35/363 (9%) Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELI---PELTNLKNALEAKS 200 L ++ + + + ++ D T A LQI++ L + +++ AL A + Sbjct: 83 LVEQLSAHAGEAGKYLHWGATTQDIMDT----ATVLQIRDGLALISRRIESVRKALAALA 138 Query: 201 KEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKT---LSFLAQGGTAV 257 + GRTHLQ A P+T G + + ++ + R+ + F GT Sbjct: 139 RNHRDTPMAGRTHLQHALPVTFGYKAAVWLSAFDRHAARLEEISPRVLVVEFSGASGTLA 198 Query: 258 GTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIA 317 G + + ++++E L + +A DA+ E L ++ SL K+A Sbjct: 199 SLGTR-----GLDVQRELARELNLGVPSITWH----SARDAVAETVQFLALVSGSLGKLA 249 Query: 318 QDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGS 377 DI + + E + + SS MP K NP E + +++ N+A Sbjct: 250 MDISIMMTTELGEVAEPFV-RHRGASSTMPQKQNPVSCELI-LAGARIVRNHATSMLDAM 307 Query: 378 QGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVT-- 435 FE + + + + + G++ R+ E L S L+ Sbjct: 308 IHDFERATGPWHLEWSAVPEGFAVASGILYQAEFMLGGLQVFPDRMRENLDHSRGLIVAE 367 Query: 436 ----ALNPKIGYDAASKVAKNAHKKGITLKESALELGV--------LTEKEFDEWVVPEH 483 AL P G A + ++ + K E+ L E+ + P + Sbjct: 368 AVMMALAPHTGRKEAHDIVYLGCRRAVEDKTGLFEVLRTMPEVAKPLGEEALRDLTDPRN 427 Query: 484 MLG 486 LG Sbjct: 428 YLG 430 >1TJU-A nrPDB Length = 474 Score = 213 bits (542), Expect = 2e-55, Method: Composition-based stats. Identities = 75/370 (20%), Positives = 139/370 (37%), Gaps = 43/370 (11%) Query: 104 DEVASG--KLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQ 161 +++ SG K+ + + VF + ANE R E++G G + Sbjct: 63 EKILSGLEKISEEWSKGVFVVKQSDEDIHTANE---RRLKELIGDIAG--------KLHT 111 Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLT 221 +S ND T + + + L +K +E + E ++ G +HLQ A P+ Sbjct: 112 GRSRNDQVVTDLKLFMKNSLSIISTHLLQLIKTLVERAAIEI-DVILPGYSHLQKAQPIR 170 Query: 222 LGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIAEQISKETG 280 Q + + +R+ K ++ L G A+ G L+ E + E Sbjct: 171 WSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALAGNPLDIDR-------EMLRSELE 223 Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENE 340 + N +A++ D +VE L L K+A+D+ + S G+ L Sbjct: 224 FASISL-NSMDAISERDFVVEFLSFATLLMIHLSKMAEDL-IIYSTSEFGFLTLS-DAFS 280 Query: 341 PGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFAGSQGQFELNVFKPVMIANLLNSI 398 GSS+MP K NP E + +V G A+I G + ++ + ++ Sbjct: 281 TGSSLMPQKKNPDSLELIRSKAGRVFGRLASILMVLKGLPSTYNKDLQEDK------EAV 334 Query: 399 RLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGI 458 + D + G+ + E + K AL P++ A+ +A +KG+ Sbjct: 335 FDVVDTLTAVLQ-VATGVISTLQISKENMEK------ALTPEM---LATDLALYLVRKGV 384 Query: 459 TLKESALELG 468 +++ G Sbjct: 385 PFRQAHTASG 394 >5V4L-A nrPDB Length = 479 Score = 211 bits (538), Expect = 4e-55, Method: Composition-based stats. Identities = 64/348 (18%), Positives = 127/348 (36%), Gaps = 21/348 (6%) Query: 149 GSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVK 208 G+ + +S I + + L+P+L + + L +K++ + Sbjct: 89 GTVAPEAAGIIHLGATSCYVTDNADLIFLRDGL-DILLPKLATVISRLANFAKQYRDLPT 147 Query: 209 IGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFD 268 +G TH Q A T+G+ + ++Q++ ++ + + L F GT GT + FD Sbjct: 148 LGFTHFQPAQLTTVGKRATLWIQELLWDLRNLQRARDDLGFRGVKGT-TGTQASFLALFD 206 Query: 269 ------VKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322 + +++++ G + P + + G L++ ++ KIA DIR Sbjct: 207 GDHAKVEALDKRVTELFGFPY-AYPV-TGQTYSRKIDADVLGPLSSFGATVHKIATDIRL 264 Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382 L + E +++ GSS M K NP + E + +M S E Sbjct: 265 LANLKEI---EEPFEKDQIGSSAMAYKRNPMRCERACSLARHLMAIYQNTLMTSSVQWLE 321 Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442 + + L D + + EG+ I +++ L + N + Sbjct: 322 RTLDDSANRRVTIPEAFLTADILLTTLQNISEGLVVYPRVIGRRISQELPFMATENIIMA 381 Query: 443 YDAASKVAKNAHKK--------GITLKESALELGVLTEKEFDEWVVPE 482 A + H+K G +KE E ++ + DE+ P Sbjct: 382 IVKAGGDRQECHEKIRVLSHQAGAVVKEEGGENDLIDRVKNDEYFKPI 429 >2E9F-A nrPDB Length = 462 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 86/400 (21%), Positives = 156/400 (39%), Gaps = 45/400 (11%) Query: 82 AIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAI 141 A + ++G L + +AI + D + FP ++ + + + + R Sbjct: 43 ARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFP---WR-----EELEDVHMNLEARLT 94 Query: 142 EILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201 E++G P + ++S ND T + + I L L + + K Sbjct: 95 ELVGP--------PGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEK 146 Query: 202 EFDHI-VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GT 259 D + V G THLQ A P+ L F Y + ++ R+ + + L+ G A+ GT Sbjct: 147 HLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGT 206 Query: 260 GLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQD 319 G F ++E G K N +A+A+ D +E ALN L ++A++ Sbjct: 207 GFPIDRHF-------TARELGFK-APMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEE 258 Query: 320 IRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFAGS 377 + L S G+ E+ GSSIMP K NP E + +V+G + G Sbjct: 259 L-ILYSTEEFGFVEVP-DAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGL 316 Query: 378 QGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTAL 437 + ++ + LL+++ D+ + G+K R+ Sbjct: 317 PLAYNKDLQEDK--EPLLDALATYRDSLRLLAA-LLPGLKWRRERMWRAAEG-------- 365 Query: 438 NPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDE 477 GY A+++A +KG+ +E+ +G L + +E Sbjct: 366 ----GYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEE 401 >1I0A-A nrPDB Length = 466 Score = 201 bits (511), Expect = 5e-52, Method: Composition-based stats. Identities = 79/370 (21%), Positives = 141/370 (38%), Gaps = 43/370 (11%) Query: 104 DEVASG--KLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQ 161 +++ SG K+ + V TQS+ + I R E++G G Q Sbjct: 61 EKILSGLEKISEESSKGVLVM---TQSDEDIQTAIERRLKELIGDIAGKLQ--------T 109 Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLT 221 +S N+ T + + I L +K +E + E I+ G THLQ A P+ Sbjct: 110 GRSRNEQVVTDLKLLLKSSISVISTHLLQLIKTLVERAAIEI-DIIMPGYTHLQKALPIR 168 Query: 222 LGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTKPGFDVKIAEQISKETG 280 Q + + +R+ K ++ L G G G L E + E Sbjct: 169 WSQFLLSHAVALTRDSERLGEVKKRITVLPLGSGVLAGNPLEIDR-------ELLRSELD 221 Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENE 340 + T N +A++ D +VE L L K+A+D+ + S G+ L Sbjct: 222 MTSITL-NSIDAISERDFVVELISVATLLMIHLSKLAEDL-IIFSTTEFGFVTLS-DAYS 278 Query: 341 PGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFAGSQGQFELNVFKPVMIANLLNSI 398 GSS++P K NP E + +V G AAI G F ++ + +L+ + Sbjct: 279 TGSSLLPQKKNPDSLELIRSKAGRVFGRLAAILMVLKGIPSTFSKDLQEDK--EAVLDVV 336 Query: 399 RLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGI 458 +T A + ++ N+ + + LT L+ ++ +A +KG+ Sbjct: 337 DTLT-AVLQVATGVISTLQINKENMEKALTPELL-------------STDLALYLVRKGM 382 Query: 459 TLKESALELG 468 ++++ G Sbjct: 383 PIRQAQTASG 392 >5XNZ-A nrPDB Length = 489 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 89/392 (22%), Positives = 145/392 (36%), Gaps = 34/392 (8%) Query: 117 LVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIA 176 + + G + AN V+ A L + + ++ +S D T + Sbjct: 92 IDLLAVARGAR--ETANPVVGLVAA--LTAAVRRDDPAAAEYVHRGSTSQDVLDTGAMLV 147 Query: 177 ASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENG 236 A ++ + +L +AL A + + GRT A P T G + +G+++ V Sbjct: 148 ARRALR-LIGDDLDRAADALAALAADHRDTPMAGRTLALHAVPTTFGLKAAGWLELVSEA 206 Query: 237 IQRVAHSLKTLSF--LAQGGTAVGT-GLNTKPGFDVKIAEQI----SKETGLKFQTAPNK 289 RVA L F GT G G T G + +++ + ETGL P Sbjct: 207 AGRVARLRDGLPFSLGGAAGTLAGYFGDRTDRGDPAVLLDRLLDAYAAETGLARPVLPWH 266 Query: 290 FEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGK 349 + + + L A +L KIA D++ L E + E SS MP K Sbjct: 267 VL----RTPVADLAAVLAFTAGALGKIAVDVQSLARTEVAEVAEPAV-EGRGASSAMPHK 321 Query: 350 VNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIAN-LLNSIRLITDAAYSF 408 NP + + +QV +T + E + L +RL AA + Sbjct: 322 RNPVLSTLIRSAALQVPALATGLTQC-LVSEDERSAGAWHAEWQPLRECLRLTGGAART- 379 Query: 409 RVHCVEGIKANEPRIHELLT------KSLMLVTALNPKIGYDAA----SKVAKNAHKKGI 458 V G++ + R+ L S + AL P +G AA ++ A A +G Sbjct: 380 AVELAAGLEVDAARMRANLDLTDGRIVSESVAVALTPLLGRQAAKELLTRAAFTAGHEGR 439 Query: 459 TLKESALEL----GVLTEKEFDEWVVPEHMLG 486 TL E EL GVL ++ ++ + P G Sbjct: 440 TLGEVLGELPELDGVLPKERWEALLDPARATG 471 >1AOS-A nrPDB Length = 464 Score = 196 bits (499), Expect = 1e-50, Method: Composition-based stats. Identities = 82/436 (18%), Positives = 152/436 (34%), Gaps = 55/436 (12%) Query: 41 PADKYWGAQTQRSF----QNFKIGGARERMPLPL-VHAFGVLKKSAAIVNESLGGLDPKI 95 + K WG + + + F A +R + V K+ + E G L Sbjct: 4 ESQKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQG----SKAYSRGLEKAGLLTKAE 59 Query: 96 SKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHP 155 I D+VA + + F+ S + ANE R E++G G Sbjct: 60 MDQILHGLDKVA-----EEWAQGTFKLNSNDEDIHTANE---RRLKELIGATAG------ 105 Query: 156 NNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQ 215 + +S ND T + + + L L L + +++ ++ G THLQ Sbjct: 106 --KLHTGRSRNDQVVTDLRLWMRQTC-STLSGLLWELIRTMVDRAEAERDVLFPGYTHLQ 162 Query: 216 DATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIAEQ 274 A P+ + + +R+ K ++ L G A+ G L E Sbjct: 163 RAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDR-------EL 215 Query: 275 ISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHEL 334 + E T N +A + D + E + L ++A+D+ L + +L Sbjct: 216 LRAELNFGAITL-NSMDATSERDFVAEFLFWRSLCMTHLSRMAEDL-ILYCTKEFSFVQL 273 Query: 335 MLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAA--ITFAGSQGQFELNVFKPVMIA 392 GSS+MP K NP E + +V G A +T G + ++ + Sbjct: 274 S-DAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDK--- 329 Query: 393 NLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKN 452 ++ ++D + ++ I L + AL+P + A+ +A Sbjct: 330 ---EAVFEVSDTMSAV-------LQVATGVISTLQIHQENMGQALSPDM---LATDLAYY 376 Query: 453 AHKKGITLKESALELG 468 +KG+ +++ G Sbjct: 377 LVRKGMPFRQAHEASG 392 >5VKW-A nrPDB Length = 482 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 59/312 (18%), Positives = 114/312 (36%), Gaps = 16/312 (5%) Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH 242 + LIP+L N+ + L + E+ + +G TH Q A T+G+ + ++Q++ ++ + Sbjct: 126 DVLIPKLVNVIDRLSKFALEYKDLPVLGWTHFQPAQLTTVGKRATLWLQELLWDLRNMVR 185 Query: 243 SLKTLSFLAQGGTAVGTGLNTKPGF--DVKIAEQISKETG--LKFQTAPNKFEALAAHDA 298 + + GT GT + F D E++ K L F + Sbjct: 186 ARNDIGLRGVKGT-TGTQASFLSLFHGDHDKVEELDKRVVELLGFDIVYPVTGQTYSRKI 244 Query: 299 IVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEAL 358 ++ L + + K A DIR L + E +++ GSS M K NP + E + Sbjct: 245 DIDVLSPLASFGATAHKFATDIRLLANLKEI---EEPFEKSQIGSSAMAYKRNPMRCERV 301 Query: 359 TQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKA 418 + + G S FE + + L S L D S ++ G+ Sbjct: 302 CSLARHLGGLFNDAVQTASVQWFERTLDDSAIRRISLPSAFLTVDILLSTMLNITSGLVV 361 Query: 419 NEPRIHELLTKSLMLVTALNPKIG--------YDAASKVAKNAHKKGITLKESALELGVL 470 I + L + N + D ++ +H+ +K+ + ++ Sbjct: 362 YPKVIERRINSELPFMATENIIMAMVEKGGSRQDCHEEIRVLSHQASAVVKQEGGDNDLI 421 Query: 471 TEKEFDEWVVPE 482 + E+ P Sbjct: 422 ERIKSTEYFKPI 433 >4EFC-A nrPDB Length = 472 Score = 184 bits (468), Expect = 6e-47, Method: Composition-based stats. Identities = 55/266 (20%), Positives = 100/266 (37%), Gaps = 14/266 (5%) Query: 154 HPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTH 213 H + +S D T + + I +P L + +L +K ++ + + RTH Sbjct: 128 HVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDW-DVPMLARTH 186 Query: 214 LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAE 273 Q A+P L +EF +++++ +++ T F G L P + + Sbjct: 187 GQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGN-FNAHLVAYPSVNWRAFA 245 Query: 274 Q--ISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGY 331 ++K GLK Q A + E +D + A L L + +D+ S G+ Sbjct: 246 DMFLAKYLGLKRQQATTQIE---NYDHLAALCDACARLHVILIDMCRDVWQYIS---MGF 299 Query: 332 HELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMI 391 + + E E GSS MP KVNP E + + ++ ++ Sbjct: 300 FKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVL 359 Query: 392 ANLLNSIRLITDAAYSFRVHCVEGIK 417 NL I A +F +G++ Sbjct: 360 RNL---GVPIGHACVAFAS-ISQGLE 381 >2QGA-B nrPDB Length = 465 Score = 184 bits (467), Expect = 8e-47, Method: Composition-based stats. Identities = 61/342 (17%), Positives = 121/342 (35%), Gaps = 27/342 (7%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 C +N + T + + + +IP L + L+ + E+ H+ + RTH Q A+ Sbjct: 120 CTSEDINNVAYATCLKAC----LNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPAS 175 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVK-IAEQISK 277 T G+E + + ++ + + + F G + +K V I + K Sbjct: 176 STTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKK 235 Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337 L + + + HD I E L +L + DI S +L + Sbjct: 236 HFNLTYSIYCTQIQ---DHDYICELCDGLARANGTLIDLCVDIWLYISN---NLLKLKVK 289 Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQ-GQFELNVFKPVMIANLLN 396 E E GSS MP KVNP E + + + + + + ++ ++ N+ + Sbjct: 290 EKEVGSSTMPHKVNPIDFENAEG-NLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGS 348 Query: 397 SIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLM-LVTALNPKIGYDA---ASKVAKN 452 S+ A S + I + + E L ++ L + + A + K Sbjct: 349 SLAYCLIAYKSVLKG-LNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQ 407 Query: 453 AHKKGITLKESAL------ELGVLTEKEFDEWVV--PEHMLG 486 +G + + + + L + D+ + P G Sbjct: 408 -FTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTG 448 >3BHG-A nrPDB Length = 459 Score = 181 bits (458), Expect = 7e-46, Method: Composition-based stats. Identities = 75/341 (21%), Positives = 130/341 (38%), Gaps = 28/341 (8%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 C +N + ++ A + IQ P + + ++ K+ + + RTH Q AT Sbjct: 124 CTSEDINNLAYALMIKQAIAQVIQ----PTIAEIMGSITLLGKQHADVAMLSRTHGQPAT 179 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277 P T+G+E +V +++ Q++A L F G + P D K Sbjct: 180 PTTMGKELVNFVARLKRPQQQLAEVLIPAKFNGAVGN-YNAHVAAYPEVDWRKHCANFVT 238 Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337 GL F + E HD I E S + + L QDI S GY + Sbjct: 239 SLGLSFNAYTTQIE---PHDGIAEVSQIMVRINNILLDYTQDIW---SYISLGYFKQKTI 292 Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAG--SQGQFELNVFKPVMIANLL 395 E GSS MP KVNP E + N I FA +Q + + ++ ++ NL Sbjct: 293 AEEVGSSTMPHKVNPIDFENAEGNLG--LSNALFIHFANKLTQSRMQRDLSDSTVLRNLG 350 Query: 396 NSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKS-LMLVTALNPKI-------GYDAAS 447 + A +S + ++ N+ + + L+++ +L A+ + Y+ Sbjct: 351 VAFSYSLIAYHSVAKG-NDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPNAYEQLK 409 Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEW--VVPEHMLG 486 ++ + LK+ L + E+ E + PE G Sbjct: 410 ELTRGQMIDAENLKKFIKTLS-IPEEAKAELMKLTPETYTG 449 >4MX2-A nrPDB Length = 480 Score = 177 bits (448), Expect = 1e-44, Method: Composition-based stats. Identities = 74/343 (21%), Positives = 127/343 (37%), Gaps = 26/343 (7%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 + +S D T + + + + IP L L L++K E+ + + RTH Q A+ Sbjct: 144 IHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEW-DVPMLARTHGQPAS 202 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAE-QIS 276 P L +EF +++++E + T F G L PG + E +S Sbjct: 203 PTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGN-FNAHLCAYPGVNWLDFGELFLS 261 Query: 277 KETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELML 336 K GL+ Q + E +D + A L L +A+D+ S GY + + Sbjct: 262 KYLGLRRQRYTTQIEH---YDNLAAICDACARLHTILMDLAKDVWQYIS---LGYFDQKV 315 Query: 337 PENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANL-- 394 E GSS MP KVNP E ++ + + ++ ++ NL Sbjct: 316 RAGEVGSSAMPHKVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGV 375 Query: 395 --------LNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAA 446 S+R D + ++ N + E + L P Y+A Sbjct: 376 PLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKP---YEAL 432 Query: 447 SKVAK-NAHKKGITLKESALELGVLTEKEFDEWVV--PEHMLG 486 + + NAH T+ +L +TE+ E + P +G Sbjct: 433 KDLTRGNAHVTEETVHRFVQQLEGITEEVRQELLAITPFTYVG 475 >4EEI-A nrPDB Length = 438 Score = 174 bits (441), Expect = 8e-44, Method: Composition-based stats. Identities = 56/261 (21%), Positives = 106/261 (40%), Gaps = 13/261 (4%) Query: 167 DTFPTVMHIAASLQIQNEL---IPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLG 223 T ++ A SLQI++ + I +L L ++L K++E I+ +GR+H A P++ G Sbjct: 92 VTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFG 151 Query: 224 QEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKF 283 Q+F G + + ++ + K Q AVG + K A+ GL Sbjct: 152 QKFLGAYVEFKRRLKDLKDFQKD-GLTVQFSGAVGNYCILTTEDEKKAAD----ILGLPV 206 Query: 284 QTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGS 343 + + + D I + +A ++ ++A +IR+L +E + + GS Sbjct: 207 EEVSTQ---VIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYE-GFSKGQKGS 262 Query: 344 SIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITD 403 S MP K NP E LT + +++ ++ +I E ++ L I Sbjct: 263 STMPHKKNPISTENLTGMA-RMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMV 321 Query: 404 AAYSFRVHCVEGIKANEPRIH 424 A + ++ + I Sbjct: 322 YALRRMKNTIDNLVVQRDIIE 342 >1YIS-A nrPDB Length = 478 Score = 174 bits (440), Expect = 9e-44, Method: Composition-based stats. Identities = 57/283 (20%), Positives = 111/283 (39%), Gaps = 15/283 (5%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 + +S IA I + ++ + + L A S + +V +GRTH Q A+ Sbjct: 102 IHLGATSCFVQDNADLIAYRDSI-DHILKRFATVIDRLAAFSLKNKEVVTVGRTHYQTAS 160 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQ-GGTAVGTGLNTKPGFDVKIAEQISK 277 +T+G+ + Q++ Q ++ + F G T T D E + Sbjct: 161 LVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGIKGATGTQDSFLTLFAGDESKVEALD- 219 Query: 278 ETGLKFQTAPNKF---EALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHEL 334 E K N+F + + +L+ L + K+ DIR L + + EL Sbjct: 220 ELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQA-----FGEL 274 Query: 335 MLP--ENEPGSSIMPGKVNPTQNEALTQVCVQVMGN-NAAITFAGSQGQFELNVFKPVMI 391 + P +++ GSS MP K NP ++E + +++ A+T QG E + Sbjct: 275 LEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINAPQEALTILADQG-LERTLDDSAGR 333 Query: 392 ANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLV 434 L+ + L +A + + EG+ + +++ + + Sbjct: 334 RMLIPDVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIAFL 376 >2PTS-A nrPDB Length = 462 Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats. Identities = 59/339 (17%), Positives = 117/339 (34%), Gaps = 24/339 (7%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 C +N + ++ A I +P L + L+ + ++ I + RTH Q AT Sbjct: 121 CTSEDINNLSHALMLKTARDEVI----LPYWRQLIDGLKDLAVQYRDIPLLSRTHGQPAT 176 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277 P T+G+E + ++E +++ G + P D + +E+ Sbjct: 177 PSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGN-YNAHIAAYPEVDWHQFSEEFVT 235 Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337 G+++ + E HD I E + L +D+ + + + Sbjct: 236 SLGIQWNPYTTQIE---PHDYIAELFDCVARFNTILIDFDRDVWGYIA---LNHFKQKTI 289 Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNS 397 E GSS MP KVNP E + +++ ++ ++ NL Sbjct: 290 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVG 349 Query: 398 IRLITDAAYSFRVHCVEGIKANEPR-IHELLTKSLMLVTALNPKI-------GYDAASKV 449 I A S + ++ N + EL +L + + Y+ ++ Sbjct: 350 IGYALIAYQSTLKGVSK-LEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKEL 408 Query: 450 AKNAHKKGITLKESALELGVLTEKEFDEW--VVPEHMLG 486 + +K+ L L E+E + P + +G Sbjct: 409 TRGKRVDAEGMKQFIDGLA-LPEEEKARLKAMTPANYIG 446 >4NSL-A nrPDB Length = 470 Score = 171 bits (433), Expect = 7e-43, Method: Composition-based stats. Identities = 60/339 (17%), Positives = 117/339 (34%), Gaps = 24/339 (7%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 C +N + ++ A I +P + NA++ + ++ I + RTH Q AT Sbjct: 135 CTSEDINNLSHALMLKTARDEVI----LPYWRQVINAVKDLATQYRDIPLLSRTHGQPAT 190 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277 P TLG+E + ++E +++ G + P D + +E+ Sbjct: 191 PSTLGKEMANVAYRMERQFRQLNQVEILGKINGAVGN-YNAHIAAYPEVDWHQFSEEFVT 249 Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337 G+++ + E HD I E + L +D+ + + + Sbjct: 250 SLGIQWNPYTTQIE---PHDYIAELFDCIARFNTILIDFDRDVWGYIA---LNHFKQKTI 303 Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNS 397 E GSS MP KVNP E + +++ ++ ++ NL Sbjct: 304 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLHHLANKLPVSRWQRDLTDSTVLRNLGVG 363 Query: 398 IRLITDAAYSFRVHCVEGIKANEPR-IHELLTKSLMLVTALNPKI-------GYDAASKV 449 I A S + ++ N + EL +L + + Y+ ++ Sbjct: 364 IGYALIAYQSTLKGVSK-LEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKEL 422 Query: 450 AKNAHKKGITLKESALELGVLTEKEFDEW--VVPEHMLG 486 + +K+ L L E E + P + +G Sbjct: 423 TRGKRVDAEGMKQFIDSLA-LPEAEKTRLKAMTPANYIG 460 >5E3V-A nrPDB Length = 380 Score = 167 bits (424), Expect = 7e-42, Method: Composition-based stats. Identities = 45/237 (18%), Positives = 86/237 (36%), Gaps = 12/237 (5%) Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218 C +N + ++ A I +P + NA++ + ++ I + RTH Q AT Sbjct: 135 CTSEDINNLSHALMLKTARDEVI----LPYWRQVINAVKDLATQYRDIPLLSRTHGQPAT 190 Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277 P TLG+E + ++E +++ G + P D + +E+ Sbjct: 191 PSTLGKEMANVAYRMERQFRQLNQVEILGKINGAVGN-YNAHIAAYPEVDWHQFSEEFVT 249 Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337 G+++ + E HD I E + L +D+ + + + Sbjct: 250 SLGIQWNPYTTQIE---PHDYIAELFDCIARFNTILIDFDRDVWGYIA---LNHFKQKTI 303 Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANL 394 E GSS MP KVNP E + +++ ++ ++ NL Sbjct: 304 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLHHLANKLPVSRWQRDLTDSTVLRNL 360 >6IG5-A nrPDB Length = 470 Score = 142 bits (357), Expect = 4e-34, Method: Composition-based stats. Identities = 76/390 (19%), Positives = 143/390 (36%), Gaps = 46/390 (11%) Query: 79 KSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISN 138 ++ +V G L + + D +A D F +V ++ + + + Sbjct: 43 RAHTMVLFRAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLV--------TDEDVHAALER 94 Query: 139 RAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEA 198 I+ +G +G + +S ND + + ++ L + AL Sbjct: 95 GLIDRVGPDLGGR-------LRAGRSRNDQVAALFRMWLRDAVRRVATGVLD-VVGALAE 146 Query: 199 KSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV- 257 ++ + G+THLQ A P+ L + + + R+ K + G A+ Sbjct: 147 QAAAHPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALA 206 Query: 258 GTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIA 317 G+ L P + I+ + G A N +A AA D E + +A L ++A Sbjct: 207 GSSLGLDP-------DAIAADLGFS-AAADNSVDATAARDFAAEAAFVFAMIAVDLSRLA 258 Query: 318 QDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFA 375 +DI + S GY L GSSIMP K NP E +++GN A + T Sbjct: 259 EDI-IVWSSTEFGYVTLH-DSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLK 316 Query: 376 GSQGQFELNVFKPV-MIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLV 434 + ++ + + + + + L+ A V + N R+ EL Sbjct: 317 AQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL----VASLTFNVQRMAELAPA----- 367 Query: 435 TALNPKIGYDAASKVAKNAHKKGITLKESA 464 GY A+ +A+ ++G+ + + Sbjct: 368 -------GYTLATDLAEWLVRQGVPFRSAH 390 >1DOF-A nrPDB Length = 403 Score = 131 bits (329), Expect = 7e-31, Method: Composition-based stats. Identities = 62/321 (19%), Positives = 131/321 (40%), Gaps = 17/321 (5%) Query: 157 NHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQD 216 + + +SND T + + + + + + L + ++++ + +GRTH Q Sbjct: 88 RYVHYGATSNDIIDTAWALLIRRALA-AVKEKARAVGDQLASMARKYKTLEMVGRTHGQW 146 Query: 217 ATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQIS 276 A P+TLG +F+ Y ++ +++A + + + A+ G AVGT + + +++ +++ Sbjct: 147 AEPITLGFKFANYYYELYIACRQLALAEEFIR--AKIGGAVGT-MASWGELGLEVRRRVA 203 Query: 277 KETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELML 336 + GL + +A ++ + AL +A ++A +IR L E Sbjct: 204 ERLGLPHHVITTQ---VAPRESFAVLASALALMAAVFERLAVEIRELSRPEIGEVVEGGG 260 Query: 337 PENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLN 396 + MP K NPT +E + + V + F E ++ + Sbjct: 261 GSS-----AMPHKANPTASERIVSLARYVRA-LTHVAFENVALWHERDLTNSANERVWIP 314 Query: 397 SIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSL--MLVTALNPKIGYDAASKVAKNAH 454 L D + + ++ + +E RI E L K+L +L ++ + AS+ A+ Sbjct: 315 EALLALDEILTSALRVLKNVYIDEERITENLQKALPYILTEFHMNRMIKEGASRA--EAY 372 Query: 455 KKGITLKESALELGVLTEKEF 475 KK +K E + Sbjct: 373 KKAKEVKALTFEYQKWPVERL 393 >4NLE-A nrPDB Length = 488 Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats. Identities = 55/334 (16%), Positives = 112/334 (33%), Gaps = 21/334 (6%) Query: 157 NHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQD 216 H ++ +S D V + ++ + + L ++ + +V GR+H Sbjct: 108 EHVHKGMTSRDLTENVEQLQIRQSLELVFSHGVA-VVARLAERAVVYRDLVMAGRSHNVA 166 Query: 217 ATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAE--- 273 A TLG+ F+ ++ + R+ + G +GT + F + + Sbjct: 167 AQATTLGKRFASAAEETLVALTRLRELIDRYPLRGVKG-PMGTAQDMLDLFGGDVGKLAD 225 Query: 274 ---QISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCG 330 ++++ G + + AL +A IR + Sbjct: 226 LERRVAEFLGFT--EVFTSVGQVYPRSLDHDVLSALVQFGAGPSSMAHTIRLMAGH---E 280 Query: 331 YHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVM 390 + GSS MP K+N E + + V + G + E +VF V+ Sbjct: 281 LVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGYASMAAELAGAQWNEGDVFCSVV 340 Query: 391 IANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTK-------SLMLVTALNPKIGY 443 L D + ++ A I L + + +L+ A+ +G Sbjct: 341 RRVALPDAFFAIDGQTETFLTVLDEFGAYPAVIQRELDRYLPFLATTRILMAAVRAGVGR 400 Query: 444 DAASKVAK-NAHKKGITLKESALELGVLTEKEFD 476 +AA +V K +A + ++E E ++ D Sbjct: 401 EAAHEVIKEHAVAVALAMREQGREPDLIDRLAGD 434 >2FEL-A nrPDB Length = 359 Score = 122 bits (305), Expect = 5e-28, Method: Composition-based stats. Identities = 56/350 (16%), Positives = 108/350 (30%), Gaps = 38/350 (10%) Query: 71 VHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNM 130 + A + + A ++AI E F + G + Sbjct: 30 IDAMIRFETALAQAEAEASIFADDEAEAIVSGLSE---------FAADMSALRHGVAKD- 79 Query: 131 NANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELT 190 E++ + + + +S D T + + + + L Sbjct: 80 ------GVVVPELIRQMRAAVAGQAADKVHFGATSQDVIDTSLMLRLKMAA-EIIATRLG 132 Query: 191 NLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFL 250 +L + L + H G T +Q A +T+ +G++ +E + R+ + F Sbjct: 133 HLIDTLGDLASRDGHKPLTGYTRMQAAIGITVADRAAGWIAPLERHLLRLETFAQN-GFA 191 Query: 251 AQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLA 310 Q G A GT + ++K GL + + D I E + L+ + Sbjct: 192 LQFGGAAGTLEKLGDNAGA-VRADLAKRLGLADRP-----QWHNQRDGIAEFANLLSLVT 245 Query: 311 CSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCV----QVM 366 +L K QDI + + GSS MP K NP E L + Q+ Sbjct: 246 GTLGKFGQDIALMA-----EIGSEIRLSGGGGSSAMPHKQNPVNAETLVTLARFNAVQIS 300 Query: 367 GNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGI 416 + ++ + E + ++ L + T + I Sbjct: 301 ALHQSLV-----QEQERSGAGWMLEWLTLPQMVTATGTSLLVAERLAAQI 345 >6G3D-A nrPDB Length = 508 Score = 110 bits (276), Expect = 1e-24, Method: Composition-based stats. Identities = 59/327 (18%), Positives = 115/327 (35%), Gaps = 36/327 (11%) Query: 157 NHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLK---NALEAKSKEFDHIVKIGRTH 213 + +S ND + ++++L+ + + A+ K+ + V + T Sbjct: 104 GKMHIGRSRNDLANAGKRMF----LRDQLLRTIEAVIGYREAVVHKAADHLDTVMVVYTQ 159 Query: 214 LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIA 272 ++A P+TLG + + + R ++ G A GTG Sbjct: 160 RKEAQPITLGHYLMAISENLAKNLDRYRELYARINLCPLGAAATAGTG-------WPLNR 212 Query: 273 EQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYH 332 ++ S G N E +A D + E + L ++A +I+ L S Sbjct: 213 DRTSALLGFDGLVV-NSIEGVAGWDHVAEHAFVNAVFLSGLSRLASEIQ-LWSTDEYQVA 270 Query: 333 ELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV----FKP 388 EL SSIMP K NP E + MG I + + +++ + +P Sbjct: 271 ELDAS-FAGTSSIMPQKKNPDSLERSRKAAFAAMGPLVGILTSLNAIEYQYSAARVELEP 329 Query: 389 VMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALN------PKIG 442 I L+ + +T + + N+ R+ + ++ +T L I Sbjct: 330 RSIDALIAATHAMTGVVRT--------LHPNKERMRQYAAENYSTMTDLTDMLVRRVGID 381 Query: 443 YDAASKVAKNAHKKGITLKESALELGV 469 Y A ++ + I A ++G+ Sbjct: 382 YREAHEIVAHVVITAIEKGIKANKIGL 408 >1GFN-A nrPDB Length = 334 Score = 35.5 bits (80), Expect = 0.056, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 34/85 (40%), Gaps = 3/85 (3%) Query: 211 RTHLQDATPLTLGQEFSGYVQQVENGIQRV---AHSLKTLSFLAQGGTAVGTGLNTKPGF 267 RT+LQ+A PL G++ + ++ + A+ +T + T Sbjct: 190 RTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQ 249 Query: 268 DVKIAEQISKETGLKFQTAPNKFEA 292 DV + Q + GL+ A K +A Sbjct: 250 DVLLVAQYQFDFGLRPSIAYTKSKA 274 >1H2B-A nrPDB Length = 359 Score = 32.8 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 35/93 (37%), Gaps = 7/93 (7%) Query: 179 LQIQNELIPELTN---LKNALEAKSKEFDHIVKI-GRTH--LQDATPLTLGQEFSGYVQQ 232 L+I++ P L + + + + G H LQ P TLG E GY+++ Sbjct: 28 LRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPKLPYTLGHENVGYIEE 87 Query: 233 VENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTK 264 V G++ + + A GT + Sbjct: 88 VAEGVEGLEKGDPVILHPAVTDGTCLACRAGED 120 >4P1M-A nrPDB Length = 123 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 12/81 (14%) Query: 403 DAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKG----- 457 DA + ++ + R T+ L+ + ALN I Y+ A + AK Sbjct: 39 DALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALN--ISYELAQEKAKTRDYAASMEQR 96 Query: 458 -----ITLKESALELGVLTEK 473 T++++ LE G +TEK Sbjct: 97 IRMLQQTIEQALLEQGRITEK 117 >5M3L-D nrPDB Length = 140 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 23/75 (30%), Gaps = 5/75 (6%) Query: 46 WGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADE 105 +GA +QR I + P L LK N L P+ + Sbjct: 59 FGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERN-----LKPEFFDIFLKHLLH 113 Query: 106 VASGKLDDHFPLVVF 120 V +L HF + Sbjct: 114 VLGDRLGTHFDFGAW 128 >4V93-B0 nrPDB Length = 158 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 23/75 (30%), Gaps = 5/75 (6%) Query: 46 WGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADE 105 +GA +QR I + P L LK N L P+ + Sbjct: 77 FGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERN-----LKPEFFDIFLKHLLH 131 Query: 106 VASGKLDDHFPLVVF 120 V +L HF + Sbjct: 132 VLGDRLGTHFDFGAW 146 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.128 0.326 Lambda K H 0.267 0.0397 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,007,449 Number of Sequences: 36641 Number of extensions: 574590 Number of successful extensions: 1920 Number of sequences better than 10.0: 53 Number of HSP's better than 10.0 without gapping: 86 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1641 Number of HSP's gapped (non-prelim): 116 length of query: 488 length of database: 10,336,785 effective HSP length: 101 effective length of query: 387 effective length of database: 6,636,044 effective search space: 2568149028 effective search space used: 2568149028 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)