BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P08417
(488 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
1YFM-A nrPDB 1011 0.0
5UPP-A nrPDB 637 0.0
4HGV-A nrPDB 602 e-172
3GTD-A nrPDB 574 e-164
6N1M-A nrPDB 573 e-164
3TV2-A nrPDB 558 e-159
1FUP-A nrPDB 542 e-154
1VDK-A nrPDB 533 e-152
3RD8-A nrPDB 424 e-119
3QBP-A nrPDB 417 e-117
4ADL-A nrPDB 412 e-115
3R6Q-A nrPDB 402 e-112
3RRP-A nrPDB 400 e-112
3OCE-A nrPDB 335 3e-92
1JSW-A nrPDB 311 3e-85
5EYT-A nrPDB 64 2e-10
1RE5-A nrPDB 61 1e-09
2PFM-A nrPDB 59 3e-09
1TJ7-A nrPDB 58 1e-08
4MX2-A nrPDB 57 2e-08
1F1O-A nrPDB 57 2e-08
2E9F-A nrPDB 55 1e-07
3BHG-A nrPDB 53 2e-07
2X75-A nrPDB 52 4e-07
1C3C-A nrPDB 52 6e-07
1Q5N-A nrPDB 51 1e-06
4EEI-A nrPDB 51 1e-06
4EFC-A nrPDB 49 6e-06
3C8T-A nrPDB 48 9e-06
5E3V-A nrPDB 47 2e-05
2J91-A nrPDB 47 2e-05
4NSL-A nrPDB 47 2e-05
1I0A-A nrPDB 45 7e-05
2PTS-A nrPDB 45 8e-05
5V4L-A nrPDB 44 1e-04
1TJU-A nrPDB 44 1e-04
5XNZ-A nrPDB 44 2e-04
2QGA-B nrPDB 43 3e-04
1YIS-A nrPDB 40 0.002
1DOF-A nrPDB 39 0.005
5VKW-A nrPDB 36 0.039
2FEL-A nrPDB 36 0.041
6IG5-A nrPDB 35 0.076
1H2B-A nrPDB 32 0.73
6GZH-B nrPDB 32 0.75
3MIA-B nrPDB 32 0.89
2PK2-A nrPDB 31 1.1
4UEJ-A nrPDB 31 1.5
5TUJ-C nrPDB 30 1.8
1A6R-A nrPDB 30 1.8
6G3D-A nrPDB 30 2.3
1AOS-A nrPDB 30 3.1
5L43-A nrPDB 30 3.1
1B65-A nrPDB 29 4.4
4JBT-A nrPDB 29 5.7
>1YFM-A nrPDB
Length = 488
Score = 1011 bits (2613), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 487/488 (99%), Positives = 488/488 (100%)
Query: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60
MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG
Sbjct: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60
Query: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120
GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF
Sbjct: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120
Query: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180
QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ
Sbjct: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180
Query: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240
IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV
Sbjct: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240
Query: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIV 300
AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPN+FEALAAHDAIV
Sbjct: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNRFEALAAHDAIV 300
Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360
ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ
Sbjct: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360
Query: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420
VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE
Sbjct: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420
Query: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480
PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV
Sbjct: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480
Query: 481 PEHMLGPK 488
PEHMLGPK
Sbjct: 481 PEHMLGPK 488
>5UPP-A nrPDB
Length = 466
Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 313/464 (67%), Positives = 376/464 (81%), Gaps = 2/464 (0%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85
+SFR E D FGE+ VP DKY+GAQT RS NFKIGG ERMP P++ AFG+LK++AA VN
Sbjct: 4 NSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVN 63
Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145
+ G LDPKI+ AI +AADEVA GKL+DHFPLVV+QTGSGTQ+NMN NEVISNRAIE+LG
Sbjct: 64 QDYG-LDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLG 122
Query: 146 GKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204
G++GSK VHPN+H N+SQSSNDTFPT MHIAA++++ L+P L L +AL+AKSKEF
Sbjct: 123 GELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFA 182
Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264
I+KIGRTH QDA PLTLGQEFSGYVQQV+ + R+ ++ + LA GGTAVGTGLNT+
Sbjct: 183 QIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTR 242
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
GF K+A +++ TGL F TAPNKFEALAAHDA+VE SGA+NT ACSL KIA DIR+LG
Sbjct: 243 IGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLG 302
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384
SGPR G EL+LPENEPGSSIMPGKVNPTQ EA+T V QVMGN+ A+T GS G FELN
Sbjct: 303 SGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELN 362
Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444
VFKP+MI N+L+S RL+ DA+ SF +CV GI+AN RI++L+ +SLMLVTALNP IGYD
Sbjct: 363 VFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYD 422
Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488
A+K+AK AHK G TLKE+A+ELG LT ++FDEWV P+ MLGPK
Sbjct: 423 KAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK 466
>4HGV-A nrPDB
Length = 495
Score = 602 bits (1553), Expect = e-172, Method: Compositional matrix adjust.
Identities = 299/463 (64%), Positives = 358/463 (77%), Gaps = 3/463 (0%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85
+S RTETD FG I V +D+YWGAQ QRS NFKIG E+ PL +V A G++K++AA N
Sbjct: 34 TSTRTETDTFGPIEVASDRYWGAQAQRSLGNFKIG--WEKQPLAIVRALGIVKQAAARAN 91
Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145
+LG LDP I AI +AA EV GKLD+HFPLVV+QTGSGTQSNMNANEV+SNRAIE+LG
Sbjct: 92 MALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLG 151
Query: 146 GKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204
G +GSK+ VHPN+H N SQSSNDT+PT MHIA + ++ ++L+P L +L ALE K K FD
Sbjct: 152 GVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFD 211
Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264
HI+KIGRTH QDATPLTLGQEFSGY QV + I+R+ +L L LAQGGTAVGTGLN
Sbjct: 212 HIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAP 271
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
GF K+AE+I+ TG+ F +APNKFEALAAHD++V GA+N A +LFKIA DIR+LG
Sbjct: 272 VGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLG 331
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384
SGPR G EL LPENEPGSSIMPGKVNPTQ EALTQVCVQV GN+AA+TFAGSQG FELN
Sbjct: 332 SGPRSGLGELSLPENEPGSSIMPGKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELN 391
Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444
V+ P+M N L S++L+ DAA SF +CV GI+A E I L +SLMLVTAL PKIGYD
Sbjct: 392 VYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYD 451
Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
A+K+AK AHK G TL+E A+ G +T++EFD V PE M+GP
Sbjct: 452 NAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGP 494
>3GTD-A nrPDB
Length = 482
Score = 574 bits (1480), Expect = e-164, Method: Compositional matrix adjust.
Identities = 281/460 (61%), Positives = 352/460 (76%), Gaps = 3/460 (0%)
Query: 27 SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNE 86
++R E+D+FGEI + YWGAQTQRS NFKI ++++MP L+ A +LKK AA VN
Sbjct: 24 NYRIESDSFGEIQIEEKFYWGAQTQRSLNNFKI--SKQKMPKILIRALAILKKCAAQVNY 81
Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146
G L+ KI+ +I +A D + +G+ +D+FPLVV+QTGSGTQ+NMN NEVI++ A E L G
Sbjct: 82 EFGDLEYKIATSIDKAIDRILAGEFEDNFPLVVWQTGSGTQTNMNMNEVIASIANEELTG 141
Query: 147 KIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205
K G K VHPN+H N+ QSSND+FPT MHIA L + +LIP L NL L+ KSK++D
Sbjct: 142 KKGGKFPVHPNDHVNKGQSSNDSFPTAMHIATVLATKQQLIPALNNLLTYLQDKSKDWDK 201
Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKP 265
I+KIGRTHLQDATPLTL QEFSGY+ Q+E ++R+ +LK + LAQGGTAVGTG+N+K
Sbjct: 202 IIKIGRTHLQDATPLTLKQEFSGYITQIEYALERIEDALKKVYLLAQGGTAVGTGINSKI 261
Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325
GFD+K A+++++ T F+TAPNKFE+LAAHDA+VE SG LNT+A SL KIA DIR LGS
Sbjct: 262 GFDIKFAQKVAEFTQQPFKTAPNKFESLAAHDALVEFSGTLNTIAVSLMKIANDIRLLGS 321
Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385
GPRCG EL LPENEPGSSIMPGKVNPTQ EALT VC QVMGN+ +T AGS G ELNV
Sbjct: 322 GPRCGLGELHLPENEPGSSIMPGKVNPTQVEALTMVCTQVMGNHVTVTIAGSNGHLELNV 381
Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445
FKPV+I N+L SI L++D+ SF HCV+G++ N RI+ L KSLMLVT LNP IGYD
Sbjct: 382 FKPVIIYNILQSIELLSDSVNSFVTHCVKGLEPNIARINTLRDKSLMLVTVLNPHIGYDN 441
Query: 446 ASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485
A+K+AK AHK GITLKE+A +L L+E+EFD+ VVPE M+
Sbjct: 442 AAKIAKEAHKYGITLKEAAKKLNFLSEEEFDKIVVPEKMI 481
>6N1M-A nrPDB
Length = 472
Score = 573 bits (1476), Expect = e-164, Method: Compositional matrix adjust.
Identities = 280/461 (60%), Positives = 349/461 (75%), Gaps = 3/461 (0%)
Query: 29 RTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESL 88
R ETD+ GEI VP+DKYWGAQT+RS +F IG ++ MP + HAFG+LKK+AA+ N L
Sbjct: 13 RVETDSMGEIEVPSDKYWGAQTERSLHHFNIG--KDIMPREVTHAFGILKKAAALTNLEL 70
Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148
G L + I QAA+EV+ G LD+HFPL V+QTGSGTQSNMNANEVISNRAIE+ GG +
Sbjct: 71 GKLPKDKADLIVQAAEEVSKGLLDEHFPLHVWQTGSGTQSNMNANEVISNRAIELAGGTL 130
Query: 149 GSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207
GSK +HPN+H N SQSSNDTFPT MHIAA++ +L+P + NL++ AK F +I+
Sbjct: 131 GSKSPIHPNDHVNMSQSSNDTFPTAMHIAAAIAFNEKLLPAVRNLRHVFAAKMDAFKNII 190
Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267
KIGRTHLQDA PLTLGQEFSGYV Q++ + R+ L L LA GGTAVGTGLNT P F
Sbjct: 191 KIGRTHLQDAVPLTLGQEFSGYVAQLDACVHRLEEVLPELYELAAGGTAVGTGLNTHPQF 250
Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327
VK+AE I+K T L F TAPNKF ALA+H+ +V GA+ TLAC+L KIA DIR+L SGP
Sbjct: 251 AVKVAEHIAKITKLPFVTAPNKFAALASHEPLVHAHGAMKTLACALMKIANDIRWLASGP 310
Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387
RCG EL++PENEPGSSIMPGKVNPTQ EA+T VC QV+GN+ A+ A SQG FELNVFK
Sbjct: 311 RCGIGELIIPENEPGSSIMPGKVNPTQCEAMTMVCAQVLGNDTAVGIADSQGNFELNVFK 370
Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447
PV+I N+L+S+ L+ D+ +SF+ C EGI+ N+P I L SLMLVTALN IGYD A+
Sbjct: 371 PVIIFNVLHSLNLLADSCHSFQEFCAEGIEPNQPVIDYYLHHSLMLVTALNQHIGYDKAA 430
Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488
K+AK AH I+L+E+A++LG+LT ++F E+V PE M+ P+
Sbjct: 431 KIAKTAHHDNISLQEAAVKLGILTAEQFAEFVKPEKMISPE 471
>3TV2-A nrPDB
Length = 459
Score = 558 bits (1437), Expect = e-159, Method: Compositional matrix adjust.
Identities = 275/459 (59%), Positives = 337/459 (73%), Gaps = 3/459 (0%)
Query: 29 RTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESL 88
R E D FGEI VPA + WGAQTQRS QNFKI + E+ L+HA ++K++AA VN L
Sbjct: 1 RMERDTFGEIAVPAARLWGAQTQRSLQNFKI--STEKQSPELIHALALIKRAAAAVNLEL 58
Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148
G L + AI AADE+ +G+ D FPL V+QTGSGTQ+NMN NEVI+NRA E+LGG+
Sbjct: 59 GVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGER 118
Query: 149 G-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207
G S+ VHPN+ N+ QSSND FPT MHIAA+ I + L+P L L+ L+AK+ F IV
Sbjct: 119 GESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIV 178
Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267
KIGRTHLQDATPLTLGQEFSGYV Q++ GI+ V +L L LAQGGTAVGTGLN P F
Sbjct: 179 KIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKF 238
Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327
+A +I + TGL F +APNKFE +AA DA+V GAL T+A SL KIA DIR+L SGP
Sbjct: 239 AAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGP 298
Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387
RCG EL +PENEPGSSIMPGKVNPTQ+EA+T +C QV GN+ A+ F G+ G FELNVF+
Sbjct: 299 RCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFR 358
Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447
P++ N+L S+RL+ D A F HC GI+ N RI LL +SLMLVTALNP IGYD A+
Sbjct: 359 PMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAA 418
Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486
++AK AHK+G TLK +AL LG +T+ +FDEWV PEHM+G
Sbjct: 419 QIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG 457
>1FUP-A nrPDB
Length = 472
Score = 542 bits (1396), Expect = e-154, Method: Compositional matrix adjust.
Identities = 270/462 (58%), Positives = 345/462 (74%), Gaps = 3/462 (0%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85
++ R+E D+ G I VPADK WGAQTQRS ++F+I + E+MP L+HA + K++AA VN
Sbjct: 2 NTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRI--STEKMPTSLIHALALTKRAAAKVN 59
Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145
E LG L + + AI+QAADEV +G+ DD FPL ++QTGSGTQSNMN NEV++NRA E+LG
Sbjct: 60 EDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLG 119
Query: 146 GKIG-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204
G G ++VHPN+ N+SQSSND FPT MH+AA L ++ +LIP+L L L KS+ F
Sbjct: 120 GVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFA 179
Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264
IVKIGRTHLQDATPLTLGQE SG+V +E+ ++ + +SL ++ LA GGTAVGTGLNT
Sbjct: 180 DIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTH 239
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
P + ++A++++ T F TAPNKFEALA DA+V+ GAL LA SL KIA D+R+L
Sbjct: 240 PEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLA 299
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384
SGPRCG E+ +PENEPGSSIMPGKVNPTQ EALT +C QVMGN+ AI G+ G FELN
Sbjct: 300 SGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELN 359
Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444
VF+P++I N L S+RL+ D SF HC GI+ N RI++LL +SLMLVTALN IGYD
Sbjct: 360 VFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYD 419
Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486
A+++AK AHK+G+TLK +AL LG L+E EFD WV PE M+G
Sbjct: 420 KAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMVG 461
>1VDK-A nrPDB
Length = 466
Score = 533 bits (1374), Expect = e-152, Method: Compositional matrix adjust.
Identities = 262/460 (56%), Positives = 324/460 (70%)
Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNES 87
+R E D GE+ VPADKYWGAQTQRS +NF+IG R RMPL ++ A+G+LKK+AA N
Sbjct: 3 YRIERDTMGEVRVPADKYWGAQTQRSLENFRIGTDRFRMPLEIIRAYGMLKKAAARANLE 62
Query: 88 LGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGK 147
LG L +I+KAI QAA+EV GK DDHFPLVVFQTGSGTQ+NMN NEVI+NRA EILG
Sbjct: 63 LGELPEEIAKAIIQAAEEVVQGKWDDHFPLVVFQTGSGTQTNMNVNEVIANRASEILGKP 122
Query: 148 IGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207
+GSK HPN+H N+ QSSNDTFPT M++A +L + L P + L AK++ FD IV
Sbjct: 123 LGSKYAHPNDHVNRGQSSNDTFPTAMYVAVALALHQRLYPAVEGLIRTFTAKAQAFDQIV 182
Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267
K+GRTHL DA P+TLGQE + Q++ + V K L LA GGTAVGTGLN P F
Sbjct: 183 KVGRTHLMDAVPITLGQEIGSWAAQLKTTLAAVKEMEKGLYNLAIGGTAVGTGLNAHPRF 242
Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327
+A+ +++ETGL F+ A N+F ALAAHD +V GA+ TLA +L KI D+R+L SGP
Sbjct: 243 GELVAKYLAEETGLPFRVAENRFAALAAHDELVNVMGAIRTLAGALMKIGNDVRWLASGP 302
Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387
G E+ +P NEPGSSIMPGKVNPTQ EALT V V+V GN+ + FAGSQG F+LNV+K
Sbjct: 303 YAGIGEITIPANEPGSSIMPGKVNPTQVEALTMVVVRVYGNDHTVAFAGSQGNFQLNVYK 362
Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447
PVM + L SI L+ DA SF H +GI+ N RI E L K+ ML TALN IGYD A+
Sbjct: 363 PVMAYSTLESINLLADAVASFDAHLAQGIEPNLERIEEYLQKNPMLATALNKAIGYDKAA 422
Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
++ K A K+ TLK++ALELG LTE+EFD VVP + P
Sbjct: 423 EIVKKALKEKKTLKQAALELGYLTEEEFDRIVVPMRLAKP 462
>3RD8-A nrPDB
Length = 489
Score = 424 bits (1090), Expect = e-119, Method: Compositional matrix adjust.
Identities = 232/448 (51%), Positives = 297/448 (66%), Gaps = 11/448 (2%)
Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG-GARERMPLPLVHAFGVLKKSAAIVNE 86
+R E D GE+ VP D W AQTQR+ +NF I ER + A G+LK + A VN+
Sbjct: 29 YRIEHDTMGEVRVPKDALWRAQTQRAVENFPISFRGLERTQ---IRALGLLKAACAQVNK 85
Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146
LG LDP+ + AI AA E+A GK DD FP+ VFQTGSGT SNMN NEVI++ A
Sbjct: 86 DLGLLDPEKADAIIAAAGEIAEGKHDDQFPIDVFQTGSGTSSNMNTNEVIASIA------ 139
Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206
VHPN+H N SQSSNDTFPT HIAA+ LIP L L +L AK+K++ +
Sbjct: 140 AANGVTVHPNDHVNMSQSSNDTFPTATHIAATEAAVRHLIPALEVLHASLAAKAKQWRTV 199
Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266
VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L LA GGTAVGTGLN G
Sbjct: 200 VKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELAIGGTAVGTGLNAPEG 259
Query: 267 FDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325
F K+ E + ETGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR++GS
Sbjct: 260 FGAKVVEVLVNETGLAELRTAVDSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGS 319
Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385
GP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAI F G+ G FELNV
Sbjct: 320 GPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVACQVVGNDAAIAFGGASGAFELNV 379
Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445
+ P+M NLL S L+++ + F C++G+ ANE R+ EL S +VT LN IGY+
Sbjct: 380 YIPMMARNLLESFTLLSNVSRLFAERCIDGLVANEERLRELAESSPSIVTPLNSAIGYEE 439
Query: 446 ASKVAKNAHKKGITLKESALELGVLTEK 473
A+KVAK A + T++++ ++ G++ +K
Sbjct: 440 AAKVAKQALAEKKTIRQTVIDRGLIGDK 467
>3QBP-A nrPDB
Length = 478
Score = 417 bits (1071), Expect = e-117, Method: Compositional matrix adjust.
Identities = 228/451 (50%), Positives = 299/451 (66%), Gaps = 11/451 (2%)
Query: 25 NSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAI 83
++ +R E D GE+ VPA W AQTQR+ +NF I G ER + A G+LK + A
Sbjct: 16 DTEYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERAQ---IRALGLLKGACAQ 72
Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143
VN LG L P+ ++AI AA E+A G+ DD FP+ VFQTGSGT SNMN NEVI++
Sbjct: 73 VNMDLGLLAPEKAEAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIAS----- 127
Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEF 203
+ G G VHPN+ N SQSSNDTFPT HIAA+ + LIP L L++AL K+ E+
Sbjct: 128 IAGANGVA-VHPNDDVNMSQSSNDTFPTATHIAATEAAVSHLIPALEILQDALATKALEW 186
Query: 204 DHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNT 263
+VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV +L L LA GGTAVGTGLN
Sbjct: 187 QSVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRATLPRLGELAIGGTAVGTGLNA 246
Query: 264 KPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
GF VK+ + +TGL + +TA N FEA AA D +VE SGAL T+A SL KIA DIR+
Sbjct: 247 PEGFGVKVVSVLVSQTGLPQLRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRW 306
Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
+GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AA+ + G+ G FE
Sbjct: 307 MGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAVAWGGANGAFE 366
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
LNV+ P+M N+L S L+T+ + F C+ G+ AN + EL S +VT LN IG
Sbjct: 367 LNVYIPMMARNILESFTLLTNVSKLFAQRCIAGLTANAEHLRELAESSPSIVTPLNSAIG 426
Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTEK 473
Y+ A+ VAK A K+ T++++ ++ G++ +K
Sbjct: 427 YEEAAAVAKQALKERKTIRQTVIDRGLIGDK 457
>4ADL-A nrPDB
Length = 495
Score = 412 bits (1059), Expect = e-115, Method: Compositional matrix adjust.
Identities = 225/465 (48%), Positives = 301/465 (64%), Gaps = 11/465 (2%)
Query: 11 TFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLP 69
+ K + + + ++++R E D GE+ VPA W AQTQR+ +NF I G ER
Sbjct: 15 SLYKKAGSMAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQ-- 72
Query: 70 LVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSN 129
+ A G+LK + A VN LG L P+ + AI AA E+A G+ DD FP+ VFQTGSGT SN
Sbjct: 73 -IRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSN 131
Query: 130 MNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPEL 189
MN NEVI++ A + G +HPN+ N SQSSNDTFPT HIAA+ LIP L
Sbjct: 132 MNTNEVIASIAAK------GGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPAL 185
Query: 190 TNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSF 249
L +AL AK+ ++ +VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV L L
Sbjct: 186 QQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGE 245
Query: 250 LAQGGTAVGTGLNTKPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNT 308
LA GGTAVGTGLN F V++ + +TGL + +TA N FEA AA D +VE SGAL T
Sbjct: 246 LAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRT 305
Query: 309 LACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGN 368
+A SL KIA DIR++GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN
Sbjct: 306 IAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGN 365
Query: 369 NAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLT 428
+AAI + G+ G FELNV+ P+M N+L S +L+T+ + F C+ G+ AN + L
Sbjct: 366 DAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAE 425
Query: 429 KSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEK 473
S +VT LN IGY+ A+ VAK A K+ T++++ ++ G++ ++
Sbjct: 426 SSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDR 470
>3R6Q-A nrPDB
Length = 468
Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust.
Identities = 203/465 (43%), Positives = 297/465 (63%), Gaps = 4/465 (0%)
Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83
MN+ R E D GE +P D Y+G QT R+ +NF I G R + L+ + G++KKSAA+
Sbjct: 1 MNTDVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGYR--IHPELIKSLGIVKKSAAL 58
Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143
N +G LD ++ + I +AADEV GK +D F + Q G+GT NMNANEVI+NRA+E+
Sbjct: 59 ANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALEL 118
Query: 144 LGGKIGS-KQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKE 202
+G + G+ ++ PN+H N SQS+ND FPT HIA L + N+LI ++ K+ E
Sbjct: 119 MGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAV-LSLLNQLIETTKYMQQEFMKKADE 177
Query: 203 FDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLN 262
F ++K+GRTHLQDA P+ LGQEF Y + + I+R+A++ L + G TAVGTGLN
Sbjct: 178 FAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLN 237
Query: 263 TKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
P + + E ++K +G ++A + +A D E S AL ++ KIA D+R
Sbjct: 238 ADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRL 297
Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
+ SGPR G E++LP +PGSSIMPGKVNP E + QV QV GN+ IT A GQFE
Sbjct: 298 MASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFE 357
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
LNV +PV+ NL+ SI ++T+ SF +C++GIKANE R+ E + KS+ ++TA+NP +G
Sbjct: 358 LNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEERMKEYVEKSIGIITAINPHVG 417
Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
Y+ A+K+A+ A+ G +++E ++ GVLTE++ +E + P M+ P
Sbjct: 418 YETAAKLAREAYLTGESIRELCIKYGVLTEEQLNEILNPYEMIHP 462
>3RRP-A nrPDB
Length = 471
Score = 400 bits (1028), Expect = e-112, Method: Compositional matrix adjust.
Identities = 228/448 (50%), Positives = 294/448 (65%), Gaps = 9/448 (2%)
Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAIVNE 86
+R E D GE+ VPA+ W AQTQR+ +NF I G ER + A G+LK + A VN+
Sbjct: 11 YRIEHDTMGEVRVPAEALWRAQTQRAVENFPISGRGLERTQ---IRALGLLKGACAQVNK 67
Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146
LG L + + AI AA E+A GK DD FP+ VFQTGSGT SNMNANEVI++ A +
Sbjct: 68 DLGLLAAEKADAIIAAAQEIADGKHDDQFPIDVFQTGSGTSSNMNANEVIASIAAQATPP 127
Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206
+ VHPN+ N SQSSNDTFPT H+AA+ +LIP L L+ AL K+K + +
Sbjct: 128 VV----VHPNDDVNMSQSSNDTFPTATHLAATEAAVRDLIPALEYLQQALATKAKAWKTV 183
Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266
VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L L GGTAVGTGLN G
Sbjct: 184 VKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELPIGGTAVGTGLNAPDG 243
Query: 267 FDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325
F K+ E + + TGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR++GS
Sbjct: 244 FGAKVVEVLKQSTGLSELKTASDSFEAQAARDGLVEGSGALKTIAASLTKIANDIRWMGS 303
Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385
GP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAIT G G FELNV
Sbjct: 304 GPLTGLGEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAITVGGLSGAFELNV 363
Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445
+ PVM NLL S L+ + + F CV+G+ ANE + L S +VT LN IGY+
Sbjct: 364 YIPVMARNLLESFTLLANVSRLFVDKCVDGLVANEDHLRTLAESSPSIVTPLNSAIGYEE 423
Query: 446 ASKVAKNAHKKGITLKESALELGVLTEK 473
A+ VAK A K+ T++++ ++ G++ +K
Sbjct: 424 AAAVAKEALKERKTIRQTVIDRGLIGDK 451
>3OCE-A nrPDB
Length = 474
Score = 335 bits (858), Expect = 3e-92, Method: Compositional matrix adjust.
Identities = 190/447 (42%), Positives = 266/447 (59%), Gaps = 6/447 (1%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAIV 84
S R E D+ GE +P D Y+G QT R+ +NF + A +P LV A ++KK+AA
Sbjct: 4 SMTRREQDSLGERDIPMDAYFGIQTLRAVENFSLSDVALNHIP-ALVRALAMVKKAAATA 62
Query: 85 NESLGGL-DPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143
N L L +PK + AI A D++ G L + F + VFQ G+GT SNMNANEVI+NRA+E
Sbjct: 63 NYKLRQLPEPKYA-AIVAACDDIIDGLLMEQFVVDVFQGGAGTSSNMNANEVIANRALEH 121
Query: 144 LGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKE 202
LG G Q +HPN+ N SQS+ND +PT + +A L QN++ L L A EAK +E
Sbjct: 122 LGRPRGDYQTIHPNDDVNMSQSTNDVYPTAVRLALLLS-QNQVQTALHRLIAAFEAKGRE 180
Query: 203 FDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLN 262
F ++KIGRT LQDA P+TLGQEF + + R+ + GGTA+GT +N
Sbjct: 181 FATVIKIGRTQLQDAVPITLGQEFEAFAATLREDTARLEEVAALFREVNLGGTAIGTRIN 240
Query: 263 TKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
+ + ++S+ +G++ + N EA A V SG L +A L KIA D+R
Sbjct: 241 ASHAYAEQAIVELSQISGIELKATGNLVEASWDTGAFVTFSGILRRIAVKLSKIANDLRL 300
Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
L SGPR G E+ LP +PGSSIMPGKVNP E++ QVC QV+GN+ +T A GQ +
Sbjct: 301 LSSGPRSGLGEIRLPAVQPGSSIMPGKVNPVIPESVNQVCYQVIGNDLTVTMAAESGQLQ 360
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
LN F+P+++ N+L+S+RL+ A + CV+GI+AN R +S+ L TAL P +G
Sbjct: 361 LNAFEPLIVYNILSSMRLLGRAMTNLAERCVDGIEANVERCRAGAEESISLATALVPVVG 420
Query: 443 YDAASKVAKNAHKKGITLKESALELGV 469
Y A+++AK A G T+ E A+ G+
Sbjct: 421 YARAAEIAKQALASGQTVMEVAISKGL 447
>1JSW-A nrPDB
Length = 478
Score = 311 bits (798), Expect = 3e-85, Method: Compositional matrix adjust.
Identities = 182/470 (38%), Positives = 272/470 (57%), Gaps = 11/470 (2%)
Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83
M+++ R E D G VPAD Y+G T R+ +NF I + V ++KK+AA+
Sbjct: 1 MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAM 60
Query: 84 VNESLGGLDPKISKAIQQAADEVAS-GKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIE 142
N+ L + ++ AI A DEV + GK D FP+ V+Q G+GT NMN NEV++N +E
Sbjct: 61 ANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLE 120
Query: 143 ILGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201
++G + G Q ++PN+H N+ QS+ND +PT IA + +L+ + L+ E K+
Sbjct: 121 LMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLI-KLVDAINQLREGFERKAV 179
Query: 202 EFDHIVKIGRTHLQDATPLTLGQEFSGYV----QQVENGIQRVAHSLKTLSFLAQGGTAV 257
EF I+K+GRT LQDA P+TLGQEF + ++V+N IQR A L ++ G TA+
Sbjct: 180 EFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKN-IQRTAELLLEVNL---GATAI 235
Query: 258 GTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIA 317
GTGLNT + +++++ TG A + EA + A V GAL LA + KI
Sbjct: 236 GTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKIC 295
Query: 318 QDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGS 377
D+R L SGPR G +E+ LPE + GSSIMP KVNP E + QVC +V+GN+ +T A
Sbjct: 296 NDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAE 355
Query: 378 QGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTAL 437
GQ +LNV +PV+ + S+ ++T+A Y+ C+ GI AN+ + S+ +VT L
Sbjct: 356 AGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYL 415
Query: 438 NPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
NP IG+ V K + G +++E LE G+LTE E D+ ++++ P
Sbjct: 416 NPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHP 465
>5EYT-A nrPDB
Length = 497
Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 77/330 (23%), Positives = 144/330 (43%), Gaps = 40/330 (12%)
Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH 242
N L+P++ + L K+ ++ + RTHLQ A P T+G+ ++Q + ++ +
Sbjct: 140 NILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLER 199
Query: 243 SLK-TLSFLAQGGTAVGTGLNTKPGFD------VKIAEQISKETGLKF------QTAPNK 289
T+ F G AVGT + F +K+ E ++K++G + QT P K
Sbjct: 200 LKNHTIRFRGAKG-AVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRK 258
Query: 290 FEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMP 347
+ +E + AL+ + ++ KI DIR L S +HE+ P + GSS MP
Sbjct: 259 VD--------IEITNALSNIGATVHKICTDIRLLSS-----FHEVEEPFETKQIGSSAMP 305
Query: 348 GKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYS 407
K NP ++E + +M + ++ S E ++ + +L L DA +
Sbjct: 306 YKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLT 365
Query: 408 FRVHCVEGIKANEPRIHELLTKS---LMLVTALNPKIGYDAAS-------KVAKNAHKKG 457
+ EG+ P + E S ++V + K+ + A+ ++ K++H+
Sbjct: 366 LLQNIAEGLIVY-PMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAA 424
Query: 458 ITLKESALELGVLTEKEFDEWVVPEHMLGP 487
+K L+ ++ + D + P H L P
Sbjct: 425 AEIKLKGLKNSLMDKLLNDYYFAPIHSLLP 454
>1RE5-A nrPDB
Length = 450
Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 94/380 (24%), Positives = 149/380 (39%), Gaps = 40/380 (10%)
Query: 131 NANEVISNRAIEI---LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELI- 186
NA N AI + LG I + + + +S D T + LQ+++ L
Sbjct: 69 NAIATAGNSAIPLVKALGKVIATGVPEAERYVHLGATSQDAMDTGL----VLQLRDALDL 124
Query: 187 --PELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH-- 242
+L L + L ++ + +GRT LQ ATP+TLG + +G + + QR+
Sbjct: 125 IEADLGKLADTLSQQALKHADTPLVGRTWLQHATPVTLGMKLAGVLGALTRHRQRLQELR 184
Query: 243 -SLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVE 301
L L F G+ G P +AE ++++ L P + D +VE
Sbjct: 185 PRLLVLQFGGASGSLAALGSKAMP-----VAEALAEQLKLTLPEQPWHTQ----RDRLVE 235
Query: 302 CSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQV 361
+ L +A SL K +DI L E P + GSS MP K NP L
Sbjct: 236 FASVLGLVAGSLGKFGRDISLLMQTEAGEVFEPSAP-GKGGSSTMPHKRNPVGAAVLIGA 294
Query: 362 CVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEP 421
+V G + + FA + E ++ L I + A EG++ +
Sbjct: 295 ATRVPGLLSTL-FAAMPQEHERSLGLWHAEWETLPDICCLVSGALRQAQVIAEGMEVDAA 353
Query: 422 RIHE--LLTKSLMLVTA----LNPKIGYDAA---------SKVAKNAHKKGITLKESALE 466
R+ LT+ L+L A L ++G D A VA+ H + + E +
Sbjct: 354 RMRRNLDLTQGLVLAEAVSIVLAQRLGRDRAHHLLEQCCQRAVAEQRHLRAVLGDEPQVS 413
Query: 467 LGVLTEKEFDEWVVPEHMLG 486
L+ +E D + P H LG
Sbjct: 414 -AELSGEELDRLLDPAHYLG 432
>2PFM-A nrPDB
Length = 444
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 12/205 (5%)
Query: 164 SSNDTFPTVMHIAASLQIQNELI-PELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTL 222
+S D T + + L+ NE+I +L N + L K+KE + + +GRTH A P T
Sbjct: 104 TSTDVVDTAL--SYILKQANEIILKDLENFVSILANKAKEHKYTIMMGRTHGVHAEPTTF 161
Query: 223 GQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLK 282
G + + ++++ ++R + T+ G AVGT N P + + E L
Sbjct: 162 GLKLGLWYEEMKRNVERFKQAANTVRVGKLSG-AVGTYANIDPFVEKYVCE------NLG 214
Query: 283 FQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPG 342
+ AP + L D L +A S+ K+A +IR L E + + G
Sbjct: 215 LEAAPISTQTL-QRDRHAHYMSTLALIATSIEKMAVEIRGLQKSETREVEE-AFAKGQKG 272
Query: 343 SSIMPGKVNPTQNEALTQVCVQVMG 367
SS MP K NP +E +T + + G
Sbjct: 273 SSAMPHKRNPIGSENMTGLARVIRG 297
>1TJ7-A nrPDB
Length = 457
Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 72/320 (22%), Positives = 130/320 (40%), Gaps = 27/320 (8%)
Query: 146 GKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205
GK+ K + +S ND T + + + +EL+ L++AL ++
Sbjct: 90 GKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTV-SELLTANRQLQSALVETAQNNQD 148
Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKP 265
V G THLQ A P+T YV+ + R+ +LK L + +G G
Sbjct: 149 AVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDV-----SPLGCGALAGT 203
Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325
+++ EQ++ G T N ++++ D ++E A L + A+D+ + +
Sbjct: 204 AYEID-REQLAGWLGFASAT-RNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNT 261
Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMG--NNAAITFAGSQGQFEL 383
G G+ EL GSS+MP K NP E + C +V G +T G +
Sbjct: 262 G-EAGFVELS-DRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNK 319
Query: 384 NVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGY 443
++ + L +++ D + ++GI+ PR E + GY
Sbjct: 320 DMQEDK--EGLFDALDTWLDCLH-MAALVLDGIQVKRPRCQEAAQQ------------GY 364
Query: 444 DAASKVAKNAHKKGITLKES 463
A+++A KG+ +E+
Sbjct: 365 ANATELADYLVAKGVPFREA 384
>4MX2-A nrPDB
Length = 480
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 61/202 (30%), Positives = 96/202 (47%), Gaps = 23/202 (11%)
Query: 162 SQSSNDT-FPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPL 220
SQ N+T P ++ A + + IP L L L++K E+D + + RTH Q A+P
Sbjct: 150 SQDINNTSIPMLLRDA----LHHHYIPTLDQLIALLKSKLPEWD-VPMLARTHGQPASPT 204
Query: 221 TLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVG---TGLNTKPGFD-VKIAEQ-I 275
L +EF +++++E QR L ++ + G A G L PG + + E +
Sbjct: 205 NLAKEFMVWIERLEE--QRTM--LLSIPNTGKFGGATGNFNAHLCAYPGVNWLDFGELFL 260
Query: 276 SKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDI-RYLGSGPRCGYHEL 334
SK GL+ Q + E AI + L+T+ L +A+D+ +Y+ GY +
Sbjct: 261 SKYLGLRRQRYTTQIEHYDNLAAICDACARLHTI---LMDLAKDVWQYIS----LGYFDQ 313
Query: 335 MLPENEPGSSIMPGKVNPTQNE 356
+ E GSS MP KVNP E
Sbjct: 314 KVRAGEVGSSAMPHKVNPIDFE 335
>1F1O-A nrPDB
Length = 431
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 51/188 (27%), Positives = 86/188 (45%), Gaps = 9/188 (4%)
Query: 180 QIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQR 239
Q + L+ +L + ++ K+KE + V +GRTH A P T G + + + ++++ ++R
Sbjct: 108 QANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAEPTTFGLKLALWHEEMKRNLER 167
Query: 240 VAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAI 299
+ + G AVGT N P + + E++ GLK AP + L D
Sbjct: 168 FKQAKAGIEVGKISG-AVGTYANIDPFVEQYVCEKL----GLK--AAPISTQTL-QRDRH 219
Query: 300 VECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALT 359
+ L +A S+ K A +IR L E + + GSS MP K NP +E +T
Sbjct: 220 ADYMATLALIATSIEKFAVEIRGLQKSETREVEEF-FAKGQKGSSAMPHKRNPIGSENMT 278
Query: 360 QVCVQVMG 367
+ + G
Sbjct: 279 GMARVIRG 286
>2E9F-A nrPDB
Length = 462
Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 85/344 (24%), Positives = 138/344 (40%), Gaps = 63/344 (18%)
Query: 155 PNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKI-GRTH 213
P + ++S ND T + + I L L + + K D + + G TH
Sbjct: 100 PGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEKHLDPLYVLPGYTH 159
Query: 214 LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIA 272
LQ A P+ L F Y + ++ R+ + + L+ G A+ GTG F
Sbjct: 160 LQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGTGFPIDRHF----- 214
Query: 273 EQISKETGLKFQTAP--NKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCG 330
++E G K AP N +A+A+ D +E ALN L ++A+++ L S G
Sbjct: 215 --TARELGFK---APMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEEL-ILYSTEEFG 268
Query: 331 YHELMLPEN-EPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPV 389
+ E+ P+ GSSIMP K NP E + +V+G F G V K +
Sbjct: 269 FVEV--PDAFATGSSIMPQKKNPDILELIRAKAGRVLG-----AFVGLSA-----VVKGL 316
Query: 390 MIA---NLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI----- 441
+A +L + DA ++R SL L+ AL P +
Sbjct: 317 PLAYNKDLQEDKEPLLDALATYR-------------------DSLRLLAALLPGLKWRRE 357
Query: 442 --------GYDAASKVAKNAHKKGITLKESALELGVLTEKEFDE 477
GY A+++A +KG+ +E+ +G L + +E
Sbjct: 358 RMWRAAEGGYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEE 401
>3BHG-A nrPDB
Length = 459
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 53/199 (26%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
C +N + ++ A + IQ P + + ++ K+ + + RTH Q AT
Sbjct: 124 CTSEDINNLAYALMIKQAIAQVIQ----PTIAEIMGSITLLGKQHADVAMLSRTHGQPAT 179
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277
P T+G+E +V +++ Q++A L F G + P D K
Sbjct: 180 PTTMGKELVNFVARLKRPQQQLAEVLIPAKFNGAVGN-YNAHVAAYPEVDWRKHCANFVT 238
Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337
GL F + E HD I E S + + L QDI S GY +
Sbjct: 239 SLGLSFNAYTTQIE---PHDGIAEVSQIMVRINNILLDYTQDI---WSYISLGYFKQKTI 292
Query: 338 ENEPGSSIMPGKVNPTQNE 356
E GSS MP KVNP E
Sbjct: 293 AEEVGSSTMPHKVNPIDFE 311
>2X75-A nrPDB
Length = 431
Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 90/344 (26%), Positives = 137/344 (39%), Gaps = 44/344 (12%)
Query: 168 TFPTVMHIAASLQIQ--NELIP-ELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQ 224
T V+ A S I+ N++I +L + L K+K + + + +GRTH A P T G
Sbjct: 93 TSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGV 152
Query: 225 EFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQ 284
+ + + +++ +QR + + G AVGT N P +I + K G+
Sbjct: 153 KMALWYTEMQRNLQRFKQVREEIEVGKMSG-AVGTFANIPP----EIESYVCKHLGIG-- 205
Query: 285 TAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSS 344
TAP + L D L +A SL K A +IR L E + + GSS
Sbjct: 206 TAPVSTQTLQ-RDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEE-AFAKGQKGSS 263
Query: 345 IMPGKVNPTQNEALTQVCVQVMGNNAAITFAG-----------SQGQFELNVFKPVMIA- 392
MP K NP +E +T + + G IT A S E + V IA
Sbjct: 264 AMPHKRNPIGSENITGISRVIRG---YITTAYENVPLWHERDISHSSAERIMLPDVTIAL 320
Query: 393 -NLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI----GYDAA- 446
LN I D F + ++ N + L+ +L+ +N + YD
Sbjct: 321 DYALNRFTNIVDRLTVFE----DNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQ 376
Query: 447 -----SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485
S K ++ I ES VLT++E DE P+H L
Sbjct: 377 PKAMISWETKTPFRELIEQDESIT--SVLTKEELDECFDPKHHL 418
>1C3C-A nrPDB
Length = 429
Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 48/177 (27%), Positives = 79/177 (44%), Gaps = 13/177 (7%)
Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244
L+ L + L + + H IGRTH A P + G + G+ +++ +QR+ ++
Sbjct: 112 LLESLKEFCDVLWEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAI 171
Query: 245 KTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSG 304
+ +S+ G AVG N P ++ E+ GLK + + + D
Sbjct: 172 EEVSYGKISG-AVGNYANVPP----EVEEKALSYLGLKPEPVSTQ---VVPRDRHAFYLS 223
Query: 305 ALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEALT 359
L +A + +IA +IR+L R E+ P + + GSS MP K NP E LT
Sbjct: 224 TLAIVAAGIERIAVEIRHL---QRTEVLEVEEPFRKGQRGSSAMPHKKNPITCERLT 277
>1Q5N-A nrPDB
Length = 454
Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 67/268 (25%), Positives = 117/268 (43%), Gaps = 28/268 (10%)
Query: 90 GLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIG 149
G+ P+ + + Q A + A K+D T +G N+ V AI +
Sbjct: 45 GVIPQSAATVIQRAAKTAIDKID----FDALATATGLAGNIAIPFVKQLTAIVKDADEDA 100
Query: 150 SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALE---AKSKEFDHI 206
++ VH +S D T A LQ ++ L ++ E ++++ + H
Sbjct: 101 ARYVHWGA------TSQDILDT----ACILQCRDALAIVQNQVQQCYETALSQAQTYRHQ 150
Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266
V +GRT LQ A P+TLG + + + + + R+ +++K +AQ G AVG+ + +
Sbjct: 151 VMMGRTWLQQALPITLGHKLARWASAFKRDLDRI-NAIKARVLVAQLGGAVGSLASLQDQ 209
Query: 267 FDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSG 326
+ + E +K+ L QTA D IVE + L + ++ K+A+D +
Sbjct: 210 GSI-VVEAYAKQLKLG-QTACTWH---GERDRIVEIASVLGIITGNVGKMARDWSLM--- 261
Query: 327 PRCGYHELMLP--ENEPGSSIMPGKVNP 352
+ E+ P + GSS MP K NP
Sbjct: 262 MQTEIAEVFEPTAKGRGGSSTMPHKRNP 289
>4EEI-A nrPDB
Length = 438
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 51/199 (25%), Positives = 90/199 (45%), Gaps = 20/199 (10%)
Query: 168 TFPTVMHIAASLQIQNEL---IPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQ 224
T ++ A SLQI++ + I +L L ++L K++E I+ +GR+H A P++ GQ
Sbjct: 93 TSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQ 152
Query: 225 EFSGYVQQVENGIQRVAHSLK---TLSFL-AQGGTAVGTGLNTKPGFDVKIAEQISKETG 280
+F G + + ++ + K T+ F A G + T + K D+ G
Sbjct: 153 KFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTTEDEKKAADI---------LG 203
Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENE 340
L + + + D I + +A ++ ++A +IR+L +E + +
Sbjct: 204 LPVEEVSTQ---VIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYE-GFSKGQ 259
Query: 341 PGSSIMPGKVNPTQNEALT 359
GSS MP K NP E LT
Sbjct: 260 KGSSTMPHKKNPISTENLT 278
>4EFC-A nrPDB
Length = 472
Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 52/199 (26%), Positives = 88/199 (44%), Gaps = 17/199 (8%)
Query: 162 SQSSNDT-FPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPL 220
SQ N+T P ++ A I +P L + +L +K ++D + + RTH Q A+P
Sbjct: 139 SQDINNTAIPMMIRDA----IVTLYLPALDGIIGSLTSKLVDWD-VPMLARTHGQPASPT 193
Query: 221 TLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQ--ISKE 278
L +EF +++++ +++ T F G L P + + ++K
Sbjct: 194 NLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGN-FNAHLVAYPSVNWRAFADMFLAKY 252
Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDI-RYLGSGPRCGYHELMLP 337
GLK Q A + E +D + A L L + +D+ +Y+ G+ + +
Sbjct: 253 LGLKRQQATTQIEN---YDHLAALCDACARLHVILIDMCRDVWQYIS----MGFFKQKVK 305
Query: 338 ENEPGSSIMPGKVNPTQNE 356
E E GSS MP KVNP E
Sbjct: 306 EGEVGSSTMPHKVNPIDFE 324
>3C8T-A nrPDB
Length = 451
Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 55/215 (25%), Positives = 93/215 (43%), Gaps = 13/215 (6%)
Query: 172 VMHIAASLQIQNELI---PELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSG 228
+M A LQI++ L + +++ AL A ++ GRTHLQ A P+T G + +
Sbjct: 107 IMDTATVLQIRDGLALISRRIESVRKALAALARNHRDTPMAGRTHLQHALPVTFGYKAAV 166
Query: 229 YVQQVENGIQRVAH-SLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAP 287
++ + R+ S + L G + L T+ G DV+ ++++E L +
Sbjct: 167 WLSAFDRHAARLEEISPRVLVVEFSGASGTLASLGTR-GLDVQ--RELARELNLGVPSIT 223
Query: 288 NKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMP 347
+A DA+ E L ++ SL K+A DI + + E + + SS MP
Sbjct: 224 WH----SARDAVAETVQFLALVSGSLGKLAMDISIMMTTELGEVAEPFV-RHRGASSTMP 278
Query: 348 GKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
K NP E L +++ N+A FE
Sbjct: 279 QKQNPVSCE-LILAGARIVRNHATSMLDAMIHDFE 312
>5E3V-A nrPDB
Length = 380
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 48/180 (26%), Positives = 77/180 (42%), Gaps = 22/180 (12%)
Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244
++P + NA++ + ++ I + RTH Q ATP TLG+E + ++E R L
Sbjct: 157 ILPYWRQVINAVKDLATQYRDIPLLSRTHGQPATPSTLGKEMANVAYRME----RQFRQL 212
Query: 245 KTLSFLAQGGTAVG---TGLNTKPGFDV-KIAEQISKETGLKFQTAPNKFEALAAHDAIV 300
+ L + AVG + P D + +E+ G+++ + E HD I
Sbjct: 213 NQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIE---PHDYIA 269
Query: 301 E---CSGALNTLACSLFKIAQDIR-YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNE 356
E C NT+ L +D+ Y+ + + E GSS MP KVNP E
Sbjct: 270 ELFDCIARFNTI---LIDFDRDVWGYIA----LNHFKQKTIAGEIGSSTMPHKVNPIDFE 322
>2J91-A nrPDB
Length = 503
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 12/188 (6%)
Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244
L+P+L + + L +KE + +G TH Q A T+G+ ++Q + +Q +
Sbjct: 153 LLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVR 212
Query: 245 KTLSFLAQGGT--AVGTGLNTKPGFDVKIAEQISKETGLK--FQTAPNKFEALAAHDAIV 300
L F GT + L G D K+ EQ+ K K F+ A +
Sbjct: 213 DDLRFRGVKGTTGTQASFLQLFEGDDHKV-EQLDKMVTEKAGFKRAFIITGQTYTRKVDI 271
Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEAL 358
E L +L S+ KI DIR L + E+ P + + GSS MP K NP ++E
Sbjct: 272 EVLSVLASLGASVHKICTDIRLLAN-----LKEMEEPFEKQQIGSSAMPYKRNPMRSERC 326
Query: 359 TQVCVQVM 366
+ +M
Sbjct: 327 CSLARHLM 334
>4NSL-A nrPDB
Length = 470
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 48/180 (26%), Positives = 77/180 (42%), Gaps = 22/180 (12%)
Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244
++P + NA++ + ++ I + RTH Q ATP TLG+E + ++E R L
Sbjct: 157 ILPYWRQVINAVKDLATQYRDIPLLSRTHGQPATPSTLGKEMANVAYRME----RQFRQL 212
Query: 245 KTLSFLAQGGTAVG---TGLNTKPGFDV-KIAEQISKETGLKFQTAPNKFEALAAHDAIV 300
+ L + AVG + P D + +E+ G+++ + E HD I
Sbjct: 213 NQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIE---PHDYIA 269
Query: 301 E---CSGALNTLACSLFKIAQDIR-YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNE 356
E C NT+ L +D+ Y+ + + E GSS MP KVNP E
Sbjct: 270 ELFDCIARFNTI---LIDFDRDVWGYIA----LNHFKQKTIAGEIGSSTMPHKVNPIDFE 322
>1I0A-A nrPDB
Length = 466
Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 63/248 (25%), Positives = 97/248 (39%), Gaps = 20/248 (8%)
Query: 126 TQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNEL 185
TQS+ + I R E++G G Q +S N+ T + + I
Sbjct: 82 TQSDEDIQTAIERRLKELIGDIAGKLQT--------GRSRNEQVVTDLKLLLKSSISVIS 133
Query: 186 IPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLK 245
L +K +E + E D I+ G THLQ A P+ Q + + +R+ K
Sbjct: 134 THLLQLIKTLVERAAIEID-IIMPGYTHLQKALPIRWSQFLLSHAVALTRDSERLGEVKK 192
Query: 246 TLSFLAQG-GTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSG 304
++ L G G G L E + E + T N +A++ D +VE
Sbjct: 193 RITVLPLGSGVLAGNPLEIDR-------ELLRSELDMTSITL-NSIDAISERDFVVELIS 244
Query: 305 ALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQ 364
L L K+A+D+ + S G+ L GSS++P K NP E + +
Sbjct: 245 VATLLMIHLSKLAEDL-IIFSTTEFGFVTLS-DAYSTGSSLLPQKKNPDSLELIRSKAGR 302
Query: 365 VMGNNAAI 372
V G AAI
Sbjct: 303 VFGRLAAI 310
>2PTS-A nrPDB
Length = 462
Score = 45.1 bits (105), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 22/180 (12%)
Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244
++P L + L+ + ++ I + RTH Q ATP T+G+E + ++E R L
Sbjct: 143 ILPYWRQLIDGLKDLAVQYRDIPLLSRTHGQPATPSTIGKEMANVAYRME----RQYRQL 198
Query: 245 KTLSFLAQGGTAVG---TGLNTKPGFDV-KIAEQISKETGLKFQTAPNKFEALAAHDAIV 300
+ L + AVG + P D + +E+ G+++ + E HD I
Sbjct: 199 NQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIE---PHDYIA 255
Query: 301 E---CSGALNTLACSLFKIAQDIR-YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNE 356
E C NT+ L +D+ Y+ + + E GSS MP KVNP E
Sbjct: 256 ELFDCVARFNTI---LIDFDRDVWGYIA----LNHFKQKTIAGEIGSSTMPHKVNPIDFE 308
>5V4L-A nrPDB
Length = 479
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 45/195 (23%), Positives = 86/195 (44%), Gaps = 24/195 (12%)
Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244
L+P+L + + L +K++ + +G TH Q A T+G+ + ++Q++ ++ + +
Sbjct: 124 LLPKLATVISRLANFAKQYRDLPTLGFTHFQPAQLTTVGKRATLWIQELLWDLRNLQRAR 183
Query: 245 KTLSFLAQGGTAVGTGLNTKPGFD------VKIAEQISKETGLKF------QTAPNKFEA 292
L F GT GT + FD + +++++ G + QT K +A
Sbjct: 184 DDLGFRGVKGT-TGTQASFLALFDGDHAKVEALDKRVTELFGFPYAYPVTGQTYSRKIDA 242
Query: 293 LAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNP 352
+ G L++ ++ KIA DIR L + E +++ GSS M K NP
Sbjct: 243 --------DVLGPLSSFGATVHKIATDIRLLANLKEI---EEPFEKDQIGSSAMAYKRNP 291
Query: 353 TQNEALTQVCVQVMG 367
+ E + +M
Sbjct: 292 MRCERACSLARHLMA 306
>1TJU-A nrPDB
Length = 474
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 67/273 (24%), Positives = 119/273 (43%), Gaps = 27/273 (9%)
Query: 104 DEVASG--KLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQ 161
+++ SG K+ + + VF + ANE R ++ L G I K H +
Sbjct: 63 EKILSGLEKISEEWSKGVFVVKQSDEDIHTANE----RRLKELIGDIAGKL-----HTGR 113
Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLT 221
S++ + + SL I + + +L +K +E + E D I+ G +HLQ A P+
Sbjct: 114 SRNDQVVTDLKLFMKNSLSIISTHLLQL--IKTLVERAAIEIDVILP-GYSHLQKAQPIR 170
Query: 222 LGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGL 281
Q + + +R+ K ++ L G A+ G + I ++ + + L
Sbjct: 171 WSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALA-------GNPLDIDREMLR-SEL 222
Query: 282 KFQT-APNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPEN- 339
+F + + N +A++ D +VE L L K+A+D+ + S G+ L L +
Sbjct: 223 EFASISLNSMDAISERDFVVEFLSFATLLMIHLSKMAEDL-IIYSTSEFGF--LTLSDAF 279
Query: 340 EPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI 372
GSS+MP K NP E + +V G A+I
Sbjct: 280 STGSSLMPQKKNPDSLELIRSKAGRVFGRLASI 312
>5XNZ-A nrPDB
Length = 489
Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 81/306 (26%), Positives = 122/306 (39%), Gaps = 43/306 (14%)
Query: 210 GRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG--GTAVGT-GLNTKPG 266
GRT A P T G + +G+++ V RVA L F G GT G G T G
Sbjct: 180 GRTLALHAVPTTFGLKAAGWLELVSEAAGRVARLRDGLPFSLGGAAGTLAGYFGDRTDRG 239
Query: 267 FDVKIAEQI----SKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
+ +++ + ETGL P + L + + + L A +L KIA D++
Sbjct: 240 DPAVLLDRLLDAYAAETGLARPVLP--WHVL--RTPVADLAAVLAFTAGALGKIAVDVQS 295
Query: 323 LGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFA----- 375
L R E+ P E SS MP K NP + + +QV +T
Sbjct: 296 LA---RTEVAEVAEPAVEGRGASSAMPHKRNPVLSTLIRSAALQVPALATGLTQCLVSED 352
Query: 376 -GSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELL------T 428
S G + ++P L +RL AA + V G++ + R+ L
Sbjct: 353 ERSAGAWHAE-WQP-----LRECLRLTGGAARTA-VELAAGLEVDAARMRANLDLTDGRI 405
Query: 429 KSLMLVTALNPKIGYDAA----SKVAKNAHKKGITLKESALEL----GVLTEKEFDEWVV 480
S + AL P +G AA ++ A A +G TL E EL GVL ++ ++ +
Sbjct: 406 VSESVAVALTPLLGRQAAKELLTRAAFTAGHEGRTLGEVLGELPELDGVLPKERWEALLD 465
Query: 481 PEHMLG 486
P G
Sbjct: 466 PARATG 471
>2QGA-B nrPDB
Length = 465
Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 46/199 (23%), Positives = 77/199 (38%), Gaps = 11/199 (5%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
C +N + T + + + +IP L + L+ + E+ H+ + RTH Q A+
Sbjct: 120 CTSEDINNVAYATCLKAC----LNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPAS 175
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVK-IAEQISK 277
T G+E + + ++ + + + F G + +K V I + K
Sbjct: 176 STTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKK 235
Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337
L + + + HD I E L +L + DI S +L +
Sbjct: 236 HFNLTYSIYCTQIQ---DHDYICELCDGLARANGTLIDLCVDIWLYISN---NLLKLKVK 289
Query: 338 ENEPGSSIMPGKVNPTQNE 356
E E GSS MP KVNP E
Sbjct: 290 EKEVGSSTMPHKVNPIDFE 308
>1YIS-A nrPDB
Length = 478
Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 83/192 (43%), Gaps = 16/192 (8%)
Query: 195 ALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLA-QG 253
A K+KE +V +GRTH Q A+ +T+G+ + Q++ Q ++ + F +G
Sbjct: 140 AFSLKNKE---VVTVGRTHYQTASLVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGIKG 196
Query: 254 GTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALA---AHDAIVECSGALNTLA 310
T T D E + E K N+F + + +L+ L
Sbjct: 197 ATGTQDSFLTLFAGDESKVEALD-ELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLG 255
Query: 311 CSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPTQNEALTQVCVQVMGN 368
+ K+ DIR L + + EL+ P +++ GSS MP K NP ++E + +++
Sbjct: 256 AAAKKVCTDIRVLQA-----FGELLEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINA 310
Query: 369 -NAAITFAGSQG 379
A+T QG
Sbjct: 311 PQEALTILADQG 322
>1DOF-A nrPDB
Length = 403
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 57/232 (24%), Positives = 105/232 (45%), Gaps = 36/232 (15%)
Query: 143 ILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIP---ELTNLKNALEAK 199
+L K G + VH +SND T A +L I+ L + + + L +
Sbjct: 80 LLEQKSGCRYVH------YGATSNDIIDT----AWALLIRRALAAVKEKARAVGDQLASM 129
Query: 200 SKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGT 259
++++ + +GRTH Q A P+TLG +F+ Y ++ +++A + + + A+ G AVGT
Sbjct: 130 ARKYKTLEMVGRTHGQWAEPITLGFKFANYYYELYIACRQLALAEEFIR--AKIGGAVGT 187
Query: 260 GLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQD 319
+ + +++ ++++ GL + +A ++ + AL +A ++A +
Sbjct: 188 -MASWGELGLEVRRRVAERLGLPHHVITTQ---VAPRESFAVLASALALMAAVFERLAVE 243
Query: 320 IRYLGSGPRCGYHELMLPE------NEPGSSIMPGKVNPTQNEALTQVCVQV 365
IR EL PE GSS MP K NPT +E + + V
Sbjct: 244 IR-----------ELSRPEIGEVVEGGGGSSAMPHKANPTASERIVSLARYV 284
>5VKW-A nrPDB
Length = 482
Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 11/182 (6%)
Query: 185 LIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSL 244
LIP+L N+ + L + E+ + +G TH Q A T+G+ + ++Q++ ++ + +
Sbjct: 128 LIPKLVNVIDRLSKFALEYKDLPVLGWTHFQPAQLTTVGKRATLWLQELLWDLRNMVRAR 187
Query: 245 KTLSFLAQGGTAVGTGLNTKPGF--DVKIAEQISKETG--LKFQTAPNKFEALAAHDAIV 300
+ GT GT + F D E++ K L F + +
Sbjct: 188 NDIGLRGVKGTT-GTQASFLSLFHGDHDKVEELDKRVVELLGFDIVYPVTGQTYSRKIDI 246
Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360
+ L + + K A DIR L + E +++ GSS M K NP + E +
Sbjct: 247 DVLSPLASFGATAHKFATDIRLLANLKEI---EEPFEKSQIGSSAMAYKRNPMRCE---R 300
Query: 361 VC 362
VC
Sbjct: 301 VC 302
>2FEL-A nrPDB
Length = 359
Score = 35.8 bits (81), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 51/205 (24%), Positives = 82/205 (40%), Gaps = 25/205 (12%)
Query: 164 SSNDTFPTVMHIAASLQIQNELIP-ELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTL 222
+S D T + + L++ E+I L +L + L + H G T +Q A +T+
Sbjct: 107 TSQDVIDTSLML--RLKMAAEIIATRLGHLIDTLGDLASRDGHKPLTGYTRMQAAIGITV 164
Query: 223 GQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGT--GLNTKPGFDVKIAEQISKETG 280
+G++ +E + R+ + F Q G A GT L G + ++K G
Sbjct: 165 ADRAAGWIAPLERHLLRL-ETFAQNGFALQFGGAAGTLEKLGDNAG---AVRADLAKRLG 220
Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYL---GSGPRCGYHELMLP 337
L ++ + D I E + L+ + +L K QDI + GS R
Sbjct: 221 L-----ADRPQWHNQRDGIAEFANLLSLVTGTLGKFGQDIALMAEIGSEIRL-------- 267
Query: 338 ENEPGSSIMPGKVNPTQNEALTQVC 362
GSS MP K NP E L +
Sbjct: 268 SGGGGSSAMPHKQNPVNAETLVTLA 292
>6IG5-A nrPDB
Length = 470
Score = 35.0 bits (79), Expect = 0.076, Method: Compositional matrix adjust.
Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 11/164 (6%)
Query: 210 GRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTKPGFD 268
G+THLQ A P+ L + + + R+ K + G G G+ L P
Sbjct: 158 GKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDP--- 214
Query: 269 VKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPR 328
+ I+ + G A N +A AA D E + +A L ++A+DI + S
Sbjct: 215 ----DAIAADLGFS-AAADNSVDATAARDFAAEAAFVFAMIAVDLSRLAEDI-IVWSSTE 268
Query: 329 CGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI 372
GY L GSSIMP K NP E +++GN A +
Sbjct: 269 FGYVTLH-DSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGL 311
>1H2B-A nrPDB
Length = 359
Score = 31.6 bits (70), Expect = 0.73, Method: Compositional matrix adjust.
Identities = 65/286 (22%), Positives = 103/286 (36%), Gaps = 80/286 (27%)
Query: 205 HIVKIGRTH--LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLA-QGGTAVGT-- 259
H+V+ G H LQ P TLG E GY+++V G++ + + A GT +
Sbjct: 59 HLVQ-GMWHELLQPKLPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRA 117
Query: 260 ------------GLNTKPGFD----------VKIAEQISKETGLKFQTAPNKFEALAAHD 297
GLN GF +K+ + IS+E + AP + A+
Sbjct: 118 GEDMHCENLEFPGLNIDGGFAEFMRTSHRSVIKLPKDISREK--LVEMAPLADAGITAYR 175
Query: 298 AIVECS--------------GALNTLACSLFK-------IAQDIRYLGSGPRCGYHELML 336
A+ + + G L +A L K IA D++ +L L
Sbjct: 176 AVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVK---------EEKLKL 226
Query: 337 PENEPGSSIMPGKVNPTQNEALTQVCVQVM------GNNAAITFAGSQGQFE-----LNV 385
E ++ + +P + QVM G N A+ F GSQ + L
Sbjct: 227 AERLGADHVVDARRDPVK---------QVMELTRGRGVNVAMDFVGSQATVDYTPYLLGR 277
Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSL 431
++I +R T S V + N +HEL+T +L
Sbjct: 278 MGRLIIVGYGGELRFPTIRVISSEVSFEGSLVGNYVELHELVTLAL 323
>6GZH-B nrPDB
Length = 726
Score = 31.6 bits (70), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRT--HLQDATPLTLGQEFSGYVQQVENGIQRV 240
N + P L +E + K+ +H++K+ T H Q++ P T + Y+QQV++ +
Sbjct: 81 NSVAPAALFLAAKVEGQPKKLEHVIKVAHTCLHPQESLPDTRSE---AYLQQVQDLVILE 137
Query: 241 AHSLKTLSF 249
+ L+TL F
Sbjct: 138 SIILQTLGF 146
>3MIA-B nrPDB
Length = 266
Score = 31.6 bits (70), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRT--HLQDATPLTLGQEFSGYVQQVENGIQRV 240
N + P L +E + K+ +H++K+ T H Q++ P T + Y+QQV++ +
Sbjct: 81 NSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSE---AYLQQVQDLVILE 137
Query: 241 AHSLKTLSF 249
+ L+TL F
Sbjct: 138 SIILQTLGF 146
>2PK2-A nrPDB
Length = 358
Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 20/69 (28%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRT--HLQDATPLTLGQEFSGYVQQVENGIQRV 240
N + P L +E + K+ +H++K+ T H Q++ P T + Y+QQV++ +
Sbjct: 81 NSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSE---AYLQQVQDLVILE 137
Query: 241 AHSLKTLSF 249
+ L+TL F
Sbjct: 138 SIILQTLGF 146
>4UEJ-A nrPDB
Length = 346
Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 11/19 (57%), Positives = 15/19 (78%)
Query: 219 PLTLGQEFSGYVQQVENGI 237
P+TLG EFSGY+ V +G+
Sbjct: 54 PITLGHEFSGYIDAVGSGV 72
>5TUJ-C nrPDB
Length = 235
Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 15/55 (27%), Positives = 28/55 (50%), Gaps = 11/55 (20%)
Query: 250 LAQGGTAVGTGLNTKP-----------GFDVKIAEQISKETGLKFQTAPNKFEAL 293
+ +G VGT + KP GFD+ +A+ ++KE G+K + P ++ +
Sbjct: 9 MKRGTLRVGTDADYKPFSFKDKNGQYTGFDIDLAKALAKELGVKVEFVPTTWDGI 63
>1A6R-A nrPDB
Length = 471
Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 355 NEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVE 414
NE L+++ V+ + NN A+ F +F ++ VM L N Y + +
Sbjct: 321 NETLSKLVVKRLQNNKAVFFGSHTPKF-MDKKTGVMDIELWN---------YPAIGYNLP 370
Query: 415 GIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALE-LGVLTEK 473
KA+ R HE L ML+T + D SK+ + K+S + L V+T+K
Sbjct: 371 QQKASRIRYHESLMTHAMLITGCH----VDETSKLPLRYRVENSWGKDSGKDGLYVMTQK 426
Query: 474 EFDEW 478
F+E+
Sbjct: 427 YFEEY 431
>6G3D-A nrPDB
Length = 508
Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 65/178 (36%), Gaps = 29/178 (16%)
Query: 201 KEFDHI--VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV- 257
K DH+ V + T ++A P+TLG + + + R ++ G A
Sbjct: 145 KAADHLDTVMVVYTQRKEAQPITLGHYLMAISENLAKNLDRYRELYARINLCPLGAAATA 204
Query: 258 GTG--LNTKP-----GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLA 310
GTG LN GFD GL N E +A D + E +
Sbjct: 205 GTGWPLNRDRTSALLGFD-----------GLVV----NSIEGVAGWDHVAEHAFVNAVFL 249
Query: 311 CSLFKIAQDIRYLGSGPRCGYHELMLPENEPG-SSIMPGKVNPTQNEALTQVCVQVMG 367
L ++A +I+ + Y L + G SSIMP K NP E + MG
Sbjct: 250 SGLSRLASEIQLWSTDE---YQVAELDASFAGTSSIMPQKKNPDSLERSRKAAFAAMG 304
>1AOS-A nrPDB
Length = 464
Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 68/298 (22%), Positives = 113/298 (37%), Gaps = 40/298 (13%)
Query: 75 GVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANE 134
G+L K A +++ L GLD + A+E A G F+ S + ANE
Sbjct: 53 GLLTK--AEMDQILHGLD--------KVAEEWAQG---------TFKLNSNDEDIHTANE 93
Query: 135 VISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKN 194
R E++G G ++H +S ND T + + Q + L L L
Sbjct: 94 ---RRLKELIGATAG--KLHTG------RSRNDQVVTDLRLWMR-QTCSTLSGLLWELIR 141
Query: 195 ALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGG 254
+ +++ ++ G THLQ A P+ + + +R+ K ++ L G
Sbjct: 142 TMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGS 201
Query: 255 TAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLF 314
A+ G D E + E T N +A + D + E + L
Sbjct: 202 GAIA---GNPLGVD---RELLRAELNFGAITL-NSMDATSERDFVAEFLFWRSLCMTHLS 254
Query: 315 KIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI 372
++A+D+ L + +L GSS+MP K NP E + +V G A +
Sbjct: 255 RMAEDL-ILYCTKEFSFVQLS-DAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGL 310
>5L43-A nrPDB
Length = 683
Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 6/48 (12%)
Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKI 209
+QSS+DT PTV +IQ ++IP+LT +A+ F I +I
Sbjct: 96 NQSSSDTNPTVQ------EIQKQIIPKLTQHGDAIHLNRPLFARIKQI 137
>1B65-A nrPDB
Length = 375
Score = 29.3 bits (64), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 9/85 (10%)
Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266
V +G+ H++D TP + QE + + + + H LK L+ A ++G G N PG
Sbjct: 230 VPVGQ-HMRDGTPQSQLQERGSIIVVLATDLPLMPHQLKRLARRA----SIGIGRNGTPG 284
Query: 267 ----FDVKIAEQISKETGLKFQTAP 287
D+ IA + + ++ ++AP
Sbjct: 285 GNNSGDIFIAFSTANQRPMQHRSAP 309
>4JBT-A nrPDB
Length = 410
Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 26/105 (24%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 340 EPGSSIMPGKVNPTQNEA-LTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSI 398
EPG + + T E LT+ +V+GN A+ AG + L + + + +
Sbjct: 210 EPGDDLTSALIYATDGETPLTEE--EVIGNLQALVAAGHETTVSLILTAVRALLSHPEQL 267
Query: 399 RLITDAAYSFRVHCVEGIKANEPRIHELL---TKSLMLVTALNPK 440
RL+ D + E ++ + P IH L+ T+ + L A+ P+
Sbjct: 268 RLVRDGEIGWETAIEETLRWDGPVIHLLMRFATEDIDLGDAVIPR 312
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
1YFM-A nrPDB 739 0.0
5UPP-A nrPDB 630 0.0
6N1M-A nrPDB 609 e-175
4HGV-A nrPDB 607 e-174
1VDK-A nrPDB 603 e-173
3GTD-A nrPDB 602 e-172
3TV2-A nrPDB 597 e-171
1FUP-A nrPDB 595 e-170
3R6Q-A nrPDB 561 e-160
4ADL-A nrPDB 550 e-157
3RD8-A nrPDB 539 e-153
3QBP-A nrPDB 536 e-152
3RRP-A nrPDB 522 e-148
1JSW-A nrPDB 509 e-144
3OCE-A nrPDB 503 e-142
1RE5-A nrPDB 268 4e-72
2X75-A nrPDB 260 1e-69
1Q5N-A nrPDB 246 1e-65
1TJ7-A nrPDB 243 1e-64
2PFM-A nrPDB 242 3e-64
1F1O-A nrPDB 237 1e-62
5EYT-A nrPDB 236 2e-62
1C3C-A nrPDB 221 7e-58
2J91-A nrPDB 220 1e-57
3C8T-A nrPDB 213 1e-55
1TJU-A nrPDB 213 2e-55
5V4L-A nrPDB 211 4e-55
2E9F-A nrPDB 209 2e-54
1I0A-A nrPDB 201 5e-52
5XNZ-A nrPDB 199 2e-51
4EFC-A nrPDB 184 6e-47
2QGA-B nrPDB 184 8e-47
3BHG-A nrPDB 181 7e-46
4MX2-A nrPDB 177 1e-44
4EEI-A nrPDB 174 8e-44
1YIS-A nrPDB 174 9e-44
2PTS-A nrPDB 171 4e-43
4NSL-A nrPDB 171 7e-43
5E3V-A nrPDB 167 7e-42
Sequences not found previously or not previously below threshold:
1AOS-A nrPDB 196 1e-50
5VKW-A nrPDB 190 1e-48
6IG5-A nrPDB 142 4e-34
1DOF-A nrPDB 131 7e-31
4NLE-A nrPDB 129 2e-30
2FEL-A nrPDB 122 5e-28
6G3D-A nrPDB 110 1e-24
1GFN-A nrPDB 35 0.056
1H2B-A nrPDB 33 0.39
4P1M-A nrPDB 30 2.5
5M3L-D nrPDB 29 3.5
4V93-B0 nrPDB 29 3.5
>1YFM-A nrPDB
Length = 488
Score = 739 bits (1907), Expect = 0.0, Method: Composition-based stats.
Identities = 487/488 (99%), Positives = 488/488 (100%)
Query: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60
MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG
Sbjct: 1 MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG 60
Query: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120
GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF
Sbjct: 61 GARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVF 120
Query: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180
QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ
Sbjct: 121 QTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQ 180
Query: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240
IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV
Sbjct: 181 IQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRV 240
Query: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIV 300
AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPN+FEALAAHDAIV
Sbjct: 241 AHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNRFEALAAHDAIV 300
Query: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360
ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ
Sbjct: 301 ECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQ 360
Query: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420
VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE
Sbjct: 361 VCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANE 420
Query: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480
PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV
Sbjct: 421 PRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480
Query: 481 PEHMLGPK 488
PEHMLGPK
Sbjct: 481 PEHMLGPK 488
>5UPP-A nrPDB
Length = 466
Score = 630 bits (1624), Expect = 0.0, Method: Composition-based stats.
Identities = 313/467 (67%), Positives = 376/467 (80%), Gaps = 2/467 (0%)
Query: 23 RMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAA 82
+SFR E D FGE+ VP DKY+GAQT RS NFKIGG ERMP P++ AFG+LK++AA
Sbjct: 1 ASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAA 60
Query: 83 IVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIE 142
VN+ G LDPKI+ AI +AADEVA GKL+DHFPLVV+QTGSGTQ+NMN NEVISNRAIE
Sbjct: 61 EVNQDYG-LDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIE 119
Query: 143 ILGGKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201
+LGG++GSK VHPN+H N+SQSSNDTFPT MHIAA++++ L+P L L +AL+AKSK
Sbjct: 120 MLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSK 179
Query: 202 EFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGL 261
EF I+KIGRTH QDA PLTLGQEFSGYVQQV+ + R+ ++ + LA GGTAVGTGL
Sbjct: 180 EFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGL 239
Query: 262 NTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIR 321
NT+ GF K+A +++ TGL F TAPNKFEALAAHDA+VE SGA+NT ACSL KIA DIR
Sbjct: 240 NTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIR 299
Query: 322 YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQF 381
+LGSGPR G EL+LPENEPGSSIMPGKVNPTQ EA+T V QVMGN+ A+T GS G F
Sbjct: 300 FLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHF 359
Query: 382 ELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI 441
ELNVFKP+MI N+L+S RL+ DA+ SF +CV GI+AN RI++L+ +SLMLVTALNP I
Sbjct: 360 ELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHI 419
Query: 442 GYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488
GYD A+K+AK AHK G TLKE+A+ELG LT ++FDEWV P+ MLGPK
Sbjct: 420 GYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK 466
>6N1M-A nrPDB
Length = 472
Score = 609 bits (1571), Expect = e-175, Method: Composition-based stats.
Identities = 280/464 (60%), Positives = 350/464 (75%), Gaps = 3/464 (0%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85
+ R ETD+ GEI VP+DKYWGAQT+RS +F IG ++ MP + HAFG+LKK+AA+ N
Sbjct: 10 AKTRVETDSMGEIEVPSDKYWGAQTERSLHHFNIG--KDIMPREVTHAFGILKKAAALTN 67
Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145
LG L + I QAA+EV+ G LD+HFPL V+QTGSGTQSNMNANEVISNRAIE+ G
Sbjct: 68 LELGKLPKDKADLIVQAAEEVSKGLLDEHFPLHVWQTGSGTQSNMNANEVISNRAIELAG 127
Query: 146 GKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204
G +GSK +HPN+H N SQSSNDTFPT MHIAA++ +L+P + NL++ AK F
Sbjct: 128 GTLGSKSPIHPNDHVNMSQSSNDTFPTAMHIAAAIAFNEKLLPAVRNLRHVFAAKMDAFK 187
Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264
+I+KIGRTHLQDA PLTLGQEFSGYV Q++ + R+ L L LA GGTAVGTGLNT
Sbjct: 188 NIIKIGRTHLQDAVPLTLGQEFSGYVAQLDACVHRLEEVLPELYELAAGGTAVGTGLNTH 247
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
P F VK+AE I+K T L F TAPNKF ALA+H+ +V GA+ TLAC+L KIA DIR+L
Sbjct: 248 PQFAVKVAEHIAKITKLPFVTAPNKFAALASHEPLVHAHGAMKTLACALMKIANDIRWLA 307
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384
SGPRCG EL++PENEPGSSIMPGKVNPTQ EA+T VC QV+GN+ A+ A SQG FELN
Sbjct: 308 SGPRCGIGELIIPENEPGSSIMPGKVNPTQCEAMTMVCAQVLGNDTAVGIADSQGNFELN 367
Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444
VFKPV+I N+L+S+ L+ D+ +SF+ C EGI+ N+P I L SLMLVTALN IGYD
Sbjct: 368 VFKPVIIFNVLHSLNLLADSCHSFQEFCAEGIEPNQPVIDYYLHHSLMLVTALNQHIGYD 427
Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGPK 488
A+K+AK AH I+L+E+A++LG+LT ++F E+V PE M+ P+
Sbjct: 428 KAAKIAKTAHHDNISLQEAAVKLGILTAEQFAEFVKPEKMISPE 471
>4HGV-A nrPDB
Length = 495
Score = 607 bits (1566), Expect = e-174, Method: Composition-based stats.
Identities = 299/463 (64%), Positives = 358/463 (77%), Gaps = 3/463 (0%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85
+S RTETD FG I V +D+YWGAQ QRS NFKIG E+ PL +V A G++K++AA N
Sbjct: 34 TSTRTETDTFGPIEVASDRYWGAQAQRSLGNFKIG--WEKQPLAIVRALGIVKQAAARAN 91
Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145
+LG LDP I AI +AA EV GKLD+HFPLVV+QTGSGTQSNMNANEV+SNRAIE+LG
Sbjct: 92 MALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLG 151
Query: 146 GKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204
G +GSK+ VHPN+H N SQSSNDT+PT MHIA + ++ ++L+P L +L ALE K K FD
Sbjct: 152 GVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFD 211
Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264
HI+KIGRTH QDATPLTLGQEFSGY QV + I+R+ +L L LAQGGTAVGTGLN
Sbjct: 212 HIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAP 271
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
GF K+AE+I+ TG+ F +APNKFEALAAHD++V GA+N A +LFKIA DIR+LG
Sbjct: 272 VGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLG 331
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384
SGPR G EL LPENEPGSSIMPGKVNPTQ EALTQVCVQV GN+AA+TFAGSQG FELN
Sbjct: 332 SGPRSGLGELSLPENEPGSSIMPGKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELN 391
Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444
V+ P+M N L S++L+ DAA SF +CV GI+A E I L +SLMLVTAL PKIGYD
Sbjct: 392 VYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYD 451
Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
A+K+AK AHK G TL+E A+ G +T++EFD V PE M+GP
Sbjct: 452 NAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGP 494
>1VDK-A nrPDB
Length = 466
Score = 603 bits (1554), Expect = e-173, Method: Composition-based stats.
Identities = 262/461 (56%), Positives = 324/461 (70%)
Query: 27 SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNE 86
+R E D GE+ VPADKYWGAQTQRS +NF+IG R RMPL ++ A+G+LKK+AA N
Sbjct: 2 EYRIERDTMGEVRVPADKYWGAQTQRSLENFRIGTDRFRMPLEIIRAYGMLKKAAARANL 61
Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146
LG L +I+KAI QAA+EV GK DDHFPLVVFQTGSGTQ+NMN NEVI+NRA EILG
Sbjct: 62 ELGELPEEIAKAIIQAAEEVVQGKWDDHFPLVVFQTGSGTQTNMNVNEVIANRASEILGK 121
Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206
+GSK HPN+H N+ QSSNDTFPT M++A +L + L P + L AK++ FD I
Sbjct: 122 PLGSKYAHPNDHVNRGQSSNDTFPTAMYVAVALALHQRLYPAVEGLIRTFTAKAQAFDQI 181
Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266
VK+GRTHL DA P+TLGQE + Q++ + V K L LA GGTAVGTGLN P
Sbjct: 182 VKVGRTHLMDAVPITLGQEIGSWAAQLKTTLAAVKEMEKGLYNLAIGGTAVGTGLNAHPR 241
Query: 267 FDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSG 326
F +A+ +++ETGL F+ A N+F ALAAHD +V GA+ TLA +L KI D+R+L SG
Sbjct: 242 FGELVAKYLAEETGLPFRVAENRFAALAAHDELVNVMGAIRTLAGALMKIGNDVRWLASG 301
Query: 327 PRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVF 386
P G E+ +P NEPGSSIMPGKVNPTQ EALT V V+V GN+ + FAGSQG F+LNV+
Sbjct: 302 PYAGIGEITIPANEPGSSIMPGKVNPTQVEALTMVVVRVYGNDHTVAFAGSQGNFQLNVY 361
Query: 387 KPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAA 446
KPVM + L SI L+ DA SF H +GI+ N RI E L K+ ML TALN IGYD A
Sbjct: 362 KPVMAYSTLESINLLADAVASFDAHLAQGIEPNLERIEEYLQKNPMLATALNKAIGYDKA 421
Query: 447 SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
+++ K A K+ TLK++ALELG LTE+EFD VVP + P
Sbjct: 422 AEIVKKALKEKKTLKQAALELGYLTEEEFDRIVVPMRLAKP 462
>3GTD-A nrPDB
Length = 482
Score = 602 bits (1551), Expect = e-172, Method: Composition-based stats.
Identities = 281/460 (61%), Positives = 351/460 (76%), Gaps = 3/460 (0%)
Query: 27 SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNE 86
++R E+D+FGEI + YWGAQTQRS NFKI +++MP L+ A +LKK AA VN
Sbjct: 24 NYRIESDSFGEIQIEEKFYWGAQTQRSLNNFKIS--KQKMPKILIRALAILKKCAAQVNY 81
Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146
G L+ KI+ +I +A D + +G+ +D+FPLVV+QTGSGTQ+NMN NEVI++ A E L G
Sbjct: 82 EFGDLEYKIATSIDKAIDRILAGEFEDNFPLVVWQTGSGTQTNMNMNEVIASIANEELTG 141
Query: 147 KIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205
K G K VHPN+H N+ QSSND+FPT MHIA L + +LIP L NL L+ KSK++D
Sbjct: 142 KKGGKFPVHPNDHVNKGQSSNDSFPTAMHIATVLATKQQLIPALNNLLTYLQDKSKDWDK 201
Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKP 265
I+KIGRTHLQDATPLTL QEFSGY+ Q+E ++R+ +LK + LAQGGTAVGTG+N+K
Sbjct: 202 IIKIGRTHLQDATPLTLKQEFSGYITQIEYALERIEDALKKVYLLAQGGTAVGTGINSKI 261
Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325
GFD+K A+++++ T F+TAPNKFE+LAAHDA+VE SG LNT+A SL KIA DIR LGS
Sbjct: 262 GFDIKFAQKVAEFTQQPFKTAPNKFESLAAHDALVEFSGTLNTIAVSLMKIANDIRLLGS 321
Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385
GPRCG EL LPENEPGSSIMPGKVNPTQ EALT VC QVMGN+ +T AGS G ELNV
Sbjct: 322 GPRCGLGELHLPENEPGSSIMPGKVNPTQVEALTMVCTQVMGNHVTVTIAGSNGHLELNV 381
Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445
FKPV+I N+L SI L++D+ SF HCV+G++ N RI+ L KSLMLVT LNP IGYD
Sbjct: 382 FKPVIIYNILQSIELLSDSVNSFVTHCVKGLEPNIARINTLRDKSLMLVTVLNPHIGYDN 441
Query: 446 ASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485
A+K+AK AHK GITLKE+A +L L+E+EFD+ VVPE M+
Sbjct: 442 AAKIAKEAHKYGITLKEAAKKLNFLSEEEFDKIVVPEKMI 481
>3TV2-A nrPDB
Length = 459
Score = 597 bits (1539), Expect = e-171, Method: Composition-based stats.
Identities = 275/459 (59%), Positives = 336/459 (73%), Gaps = 3/459 (0%)
Query: 29 RTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESL 88
R E D FGEI VPA + WGAQTQRS QNFKI E+ L+HA ++K++AA VN L
Sbjct: 1 RMERDTFGEIAVPAARLWGAQTQRSLQNFKIS--TEKQSPELIHALALIKRAAAAVNLEL 58
Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148
G L + AI AADE+ +G+ D FPL V+QTGSGTQ+NMN NEVI+NRA E+LGG+
Sbjct: 59 GVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGER 118
Query: 149 G-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIV 207
G S+ VHPN+ N+ QSSND FPT MHIAA+ I + L+P L L+ L+AK+ F IV
Sbjct: 119 GESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIV 178
Query: 208 KIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGF 267
KIGRTHLQDATPLTLGQEFSGYV Q++ GI+ V +L L LAQGGTAVGTGLN P F
Sbjct: 179 KIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKF 238
Query: 268 DVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGP 327
+A +I + TGL F +APNKFE +AA DA+V GAL T+A SL KIA DIR+L SGP
Sbjct: 239 AAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGP 298
Query: 328 RCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFK 387
RCG EL +PENEPGSSIMPGKVNPTQ+EA+T +C QV GN+ A+ F G+ G FELNVF+
Sbjct: 299 RCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFR 358
Query: 388 PVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAAS 447
P++ N+L S+RL+ D A F HC GI+ N RI LL +SLMLVTALNP IGYD A+
Sbjct: 359 PMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAA 418
Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486
++AK AHK+G TLK +AL LG +T+ +FDEWV PEHM+G
Sbjct: 419 QIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG 457
>1FUP-A nrPDB
Length = 472
Score = 595 bits (1534), Expect = e-170, Method: Composition-based stats.
Identities = 270/462 (58%), Positives = 344/462 (74%), Gaps = 3/462 (0%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85
++ R+E D+ G I VPADK WGAQTQRS ++F+I E+MP L+HA + K++AA VN
Sbjct: 2 NTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRIS--TEKMPTSLIHALALTKRAAAKVN 59
Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145
E LG L + + AI+QAADEV +G+ DD FPL ++QTGSGTQSNMN NEV++NRA E+LG
Sbjct: 60 EDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLG 119
Query: 146 GKIG-SKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204
G G ++VHPN+ N+SQSSND FPT MH+AA L ++ +LIP+L L L KS+ F
Sbjct: 120 GVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFA 179
Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264
IVKIGRTHLQDATPLTLGQE SG+V +E+ ++ + +SL ++ LA GGTAVGTGLNT
Sbjct: 180 DIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTH 239
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
P + ++A++++ T F TAPNKFEALA DA+V+ GAL LA SL KIA D+R+L
Sbjct: 240 PEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLA 299
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384
SGPRCG E+ +PENEPGSSIMPGKVNPTQ EALT +C QVMGN+ AI G+ G FELN
Sbjct: 300 SGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELN 359
Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444
VF+P++I N L S+RL+ D SF HC GI+ N RI++LL +SLMLVTALN IGYD
Sbjct: 360 VFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYD 419
Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486
A+++AK AHK+G+TLK +AL LG L+E EFD WV PE M+G
Sbjct: 420 KAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMVG 461
>3R6Q-A nrPDB
Length = 468
Score = 561 bits (1446), Expect = e-160, Method: Composition-based stats.
Identities = 203/465 (43%), Positives = 297/465 (63%), Gaps = 4/465 (0%)
Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83
MN+ R E D GE +P D Y+G QT R+ +NF I G R+ L+ + G++KKSAA+
Sbjct: 1 MNTDVRIEKDFLGEKEIPKDAYYGVQTIRATENFPITGY--RIHPELIKSLGIVKKSAAL 58
Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143
N +G LD ++ + I +AADEV GK +D F + Q G+GT NMNANEVI+NRA+E+
Sbjct: 59 ANMEVGLLDKEVGQYIVKAADEVIEGKWNDQFIVDPIQGGAGTSINMNANEVIANRALEL 118
Query: 144 LGGKIGSK-QVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKE 202
+G + G+ ++ PN+H N SQS+ND FPT HIA L + N+LI ++ K+ E
Sbjct: 119 MGEEKGNYSKISPNSHVNMSQSTNDAFPTATHIAV-LSLLNQLIETTKYMQQEFMKKADE 177
Query: 203 FDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLN 262
F ++K+GRTHLQDA P+ LGQEF Y + + I+R+A++ L + G TAVGTGLN
Sbjct: 178 FAGVIKMGRTHLQDAVPILLGQEFEAYARVIARDIERIANTRNNLYDINMGATAVGTGLN 237
Query: 263 TKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
P + + E ++K +G ++A + +A D E S AL ++ KIA D+R
Sbjct: 238 ADPEYISIVTEHLAKFSGHPLRSAQHLVDATQNTDCYTEVSSALKVCMINMSKIANDLRL 297
Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
+ SGPR G E++LP +PGSSIMPGKVNP E + QV QV GN+ IT A GQFE
Sbjct: 298 MASGPRAGLSEIVLPARQPGSSIMPGKVNPVMPEVMNQVAFQVFGNDLTITSASEAGQFE 357
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
LNV +PV+ NL+ SI ++T+ SF +C++GIKANE R+ E + KS+ ++TA+NP +G
Sbjct: 358 LNVMEPVLFFNLIQSISIMTNVFKSFTENCLKGIKANEERMKEYVEKSIGIITAINPHVG 417
Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
Y+ A+K+A+ A+ G +++E ++ GVLTE++ +E + P M+ P
Sbjct: 418 YETAAKLAREAYLTGESIRELCIKYGVLTEEQLNEILNPYEMIHP 462
>4ADL-A nrPDB
Length = 495
Score = 550 bits (1418), Expect = e-157, Method: Composition-based stats.
Identities = 227/484 (46%), Positives = 306/484 (63%), Gaps = 15/484 (3%)
Query: 11 TFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLP 69
+ K + + + ++++R E D GE+ VPA W AQTQR+ +NF I G ER
Sbjct: 15 SLYKKAGSMAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQ-- 72
Query: 70 LVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSN 129
+ A G+LK + A VN LG L P+ + AI AA E+A G+ DD FP+ VFQTGSGT SN
Sbjct: 73 -IRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSN 131
Query: 130 MNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPEL 189
MN NEVI++ A + G +HPN+ N SQSSNDTFPT HIAA+ LIP L
Sbjct: 132 MNTNEVIASIAAK------GGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPAL 185
Query: 190 TNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSF 249
L +AL AK+ ++ +VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV L L
Sbjct: 186 QQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGE 245
Query: 250 LAQGGTAVGTGLNTKPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNT 308
LA GGTAVGTGLN F V++ + +TGL + +TA N FEA AA D +VE SGAL T
Sbjct: 246 LAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRT 305
Query: 309 LACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGN 368
+A SL KIA DIR++GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN
Sbjct: 306 IAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGN 365
Query: 369 NAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLT 428
+AAI + G+ G FELNV+ P+M N+L S +L+T+ + F C+ G+ AN + L
Sbjct: 366 DAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAE 425
Query: 429 KSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHM 484
S +VT LN IGY+ A+ VAK A K+ T++++ ++ G++ + ++ D + M
Sbjct: 426 SSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAM 485
Query: 485 LGPK 488
+
Sbjct: 486 AKAE 489
>3RD8-A nrPDB
Length = 489
Score = 539 bits (1388), Expect = e-153, Method: Composition-based stats.
Identities = 234/466 (50%), Positives = 302/466 (64%), Gaps = 15/466 (3%)
Query: 25 NSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIG-GARERMPLPLVHAFGVLKKSAAI 83
+ +R E D GE+ VP D W AQTQR+ +NF I ER + A G+LK + A
Sbjct: 26 DVEYRIEHDTMGEVRVPKDALWRAQTQRAVENFPISFRGLERTQ---IRALGLLKAACAQ 82
Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143
VN+ LG LDP+ + AI AA E+A GK DD FP+ VFQTGSGT SNMN NEVI++ A
Sbjct: 83 VNKDLGLLDPEKADAIIAAAGEIAEGKHDDQFPIDVFQTGSGTSSNMNTNEVIASIAA-- 140
Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEF 203
VHPN+H N SQSSNDTFPT HIAA+ LIP L L +L AK+K++
Sbjct: 141 ----ANGVTVHPNDHVNMSQSSNDTFPTATHIAATEAAVRHLIPALEVLHASLAAKAKQW 196
Query: 204 DHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNT 263
+VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L LA GGTAVGTGLN
Sbjct: 197 RTVVKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELAIGGTAVGTGLNA 256
Query: 264 KPGFDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
GF K+ E + ETGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR+
Sbjct: 257 PEGFGAKVVEVLVNETGLAELRTAVDSFEAQAARDGLVEASGALRTIAVSLTKIANDIRW 316
Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
+GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAI F G+ G FE
Sbjct: 317 MGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVACQVVGNDAAIAFGGASGAFE 376
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
LNV+ P+M NLL S L+++ + F C++G+ ANE R+ EL S +VT LN IG
Sbjct: 377 LNVYIPMMARNLLESFTLLSNVSRLFAERCIDGLVANEERLRELAESSPSIVTPLNSAIG 436
Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHM 484
Y+ A+KVAK A + T++++ ++ G++ + +E D + M
Sbjct: 437 YEEAAKVAKQALAEKKTIRQTVIDRGLIGDKLSLEELDRRLDVLAM 482
>3QBP-A nrPDB
Length = 478
Score = 536 bits (1380), Expect = e-152, Method: Composition-based stats.
Identities = 229/466 (49%), Positives = 300/466 (64%), Gaps = 15/466 (3%)
Query: 25 NSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAI 83
++ +R E D GE+ VPA W AQTQR+ +NF I G ER + A G+LK + A
Sbjct: 16 DTEYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERAQ---IRALGLLKGACAQ 72
Query: 84 VNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEI 143
VN LG L P+ ++AI AA E+A G+ DD FP+ VFQTGSGT SNMN NEVI++ A
Sbjct: 73 VNMDLGLLAPEKAEAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIA--- 129
Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEF 203
VHPN+ N SQSSNDTFPT HIAA+ + LIP L L++AL K+ E+
Sbjct: 130 ---GANGVAVHPNDDVNMSQSSNDTFPTATHIAATEAAVSHLIPALEILQDALATKALEW 186
Query: 204 DHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNT 263
+VK GRTHL DA P+TLGQEFSGY +Q+E GI+RV +L L LA GGTAVGTGLN
Sbjct: 187 QSVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRATLPRLGELAIGGTAVGTGLNA 246
Query: 264 KPGFDVKIAEQISKETGLK-FQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
GF VK+ + +TGL +TA N FEA AA D +VE SGAL T+A SL KIA DIR+
Sbjct: 247 PEGFGVKVVSVLVSQTGLPQLRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRW 306
Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
+GSGP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AA+ + G+ G FE
Sbjct: 307 MGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAVAWGGANGAFE 366
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
LNV+ P+M N+L S L+T+ + F C+ G+ AN + EL S +VT LN IG
Sbjct: 367 LNVYIPMMARNILESFTLLTNVSKLFAQRCIAGLTANAEHLRELAESSPSIVTPLNSAIG 426
Query: 443 YDAASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHM 484
Y+ A+ VAK A K+ T++++ ++ G++ + +E D + M
Sbjct: 427 YEEAAAVAKQALKERKTIRQTVIDRGLIGDKLSLEELDRRLDVLAM 472
>3RRP-A nrPDB
Length = 471
Score = 522 bits (1344), Expect = e-148, Method: Composition-based stats.
Identities = 231/467 (49%), Positives = 299/467 (64%), Gaps = 13/467 (2%)
Query: 28 FRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGG-ARERMPLPLVHAFGVLKKSAAIVNE 86
+R E D GE+ VPA+ W AQTQR+ +NF I G ER + A G+LK + A VN+
Sbjct: 11 YRIEHDTMGEVRVPAEALWRAQTQRAVENFPISGRGLERTQ---IRALGLLKGACAQVNK 67
Query: 87 SLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGG 146
LG L + + AI AA E+A GK DD FP+ VFQTGSGT SNMNANEVI++ A +
Sbjct: 68 DLGLLAAEKADAIIAAAQEIADGKHDDQFPIDVFQTGSGTSSNMNANEVIASIAAQATPP 127
Query: 147 KIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHI 206
VHPN+ N SQSSNDTFPT H+AA+ +LIP L L+ AL K+K + +
Sbjct: 128 V----VVHPNDDVNMSQSSNDTFPTATHLAATEAAVRDLIPALEYLQQALATKAKAWKTV 183
Query: 207 VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPG 266
VK GRTHL DA P+TLGQEF GY +Q+E GI+RV +L L L GGTAVGTGLN G
Sbjct: 184 VKSGRTHLMDAVPVTLGQEFGGYARQIEAGIERVKATLPRLGELPIGGTAVGTGLNAPDG 243
Query: 267 FDVKIAEQISKETGL-KFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325
F K+ E + + TGL + +TA + FEA AA D +VE SGAL T+A SL KIA DIR++GS
Sbjct: 244 FGAKVVEVLKQSTGLSELKTASDSFEAQAARDGLVEGSGALKTIAASLTKIANDIRWMGS 303
Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385
GP G E+ LP+ +PGSSIMPGKVNP EA+TQV QV+GN+AAIT G G FELNV
Sbjct: 304 GPLTGLGEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAITVGGLSGAFELNV 363
Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDA 445
+ PVM NLL S L+ + + F CV+G+ ANE + L S +VT LN IGY+
Sbjct: 364 YIPVMARNLLESFTLLANVSRLFVDKCVDGLVANEDHLRTLAESSPSIVTPLNSAIGYEE 423
Query: 446 ASKVAKNAHKKGITLKESALELGVLTE----KEFDEWVVPEHMLGPK 488
A+ VAK A K+ T++++ ++ G++ + +E D+ + M K
Sbjct: 424 AAAVAKEALKERKTIRQTVIDRGLIGDKLSIEELDKRLDVLAMAKVK 470
>1JSW-A nrPDB
Length = 478
Score = 509 bits (1310), Expect = e-144, Method: Composition-based stats.
Identities = 176/466 (37%), Positives = 269/466 (57%), Gaps = 3/466 (0%)
Query: 24 MNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAI 83
M+++ R E D G VPAD Y+G T R+ +NF I + V ++KK+AA+
Sbjct: 1 MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAM 60
Query: 84 VNESLGGLDPKISKAIQQAADEVAS-GKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIE 142
N+ L + ++ AI A DEV + GK D FP+ V+Q G+GT NMN NEV++N +E
Sbjct: 61 ANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLE 120
Query: 143 ILGGKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201
++G + G Q ++PN+H N+ QS+ND +PT IA + +L+ + L+ E K+
Sbjct: 121 LMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLI-KLVDAINQLREGFERKAV 179
Query: 202 EFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGL 261
EF I+K+GRT LQDA P+TLGQEF + ++ ++ + + + L + G TA+GTGL
Sbjct: 180 EFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGL 239
Query: 262 NTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIR 321
NT + +++++ TG A + EA + A V GAL LA + KI D+R
Sbjct: 240 NTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLR 299
Query: 322 YLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQF 381
L SGPR G +E+ LPE + GSSIMP KVNP E + QVC +V+GN+ +T A GQ
Sbjct: 300 LLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQL 359
Query: 382 ELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKI 441
+LNV +PV+ + S+ ++T+A Y+ C+ GI AN+ + S+ +VT LNP I
Sbjct: 360 QLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFI 419
Query: 442 GYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
G+ V K + G +++E LE G+LTE E D+ ++++ P
Sbjct: 420 GHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHP 465
>3OCE-A nrPDB
Length = 474
Score = 503 bits (1294), Expect = e-142, Method: Composition-based stats.
Identities = 190/463 (41%), Positives = 263/463 (56%), Gaps = 3/463 (0%)
Query: 26 SSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVN 85
S R E D+ GE +P D Y+G QT R+ +NF + LV A ++KK+AA N
Sbjct: 4 SMTRREQDSLGERDIPMDAYFGIQTLRAVENFSLSDVALNHIPALVRALAMVKKAAATAN 63
Query: 86 ESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILG 145
L L AI A D++ G L + F + VFQ G+GT SNMNANEVI+NRA+E LG
Sbjct: 64 YKLRQLPEPKYAAIVAACDDIIDGLLMEQFVVDVFQGGAGTSSNMNANEVIANRALEHLG 123
Query: 146 GKIGSKQ-VHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFD 204
G Q +HPN+ N SQS+ND +PT + +A L QN++ L L A EAK +EF
Sbjct: 124 RPRGDYQTIHPNDDVNMSQSTNDVYPTAVRLALLLS-QNQVQTALHRLIAAFEAKGREFA 182
Query: 205 HIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTK 264
++KIGRT LQDA P+TLGQEF + + R+ + GGTA+GT +N
Sbjct: 183 TVIKIGRTQLQDAVPITLGQEFEAFAATLREDTARLEEVAALFREVNLGGTAIGTRINAS 242
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
+ + ++S+ +G++ + N EA A V SG L +A L KIA D+R L
Sbjct: 243 HAYAEQAIVELSQISGIELKATGNLVEASWDTGAFVTFSGILRRIAVKLSKIANDLRLLS 302
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELN 384
SGPR G E+ LP +PGSSIMPGKVNP E++ QVC QV+GN+ +T A GQ +LN
Sbjct: 303 SGPRSGLGEIRLPAVQPGSSIMPGKVNPVIPESVNQVCYQVIGNDLTVTMAAESGQLQLN 362
Query: 385 VFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYD 444
F+P+++ N+L+S+RL+ A + CV+GI+AN R +S+ L TAL P +GY
Sbjct: 363 AFEPLIVYNILSSMRLLGRAMTNLAERCVDGIEANVERCRAGAEESISLATALVPVVGYA 422
Query: 445 AASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLGP 487
A+++AK A G T+ E A+ G L + P M P
Sbjct: 423 RAAEIAKQALASGQTVMEVAISKG-LDASALTIMLDPLRMAFP 464
>1RE5-A nrPDB
Length = 450
Score = 268 bits (685), Expect = 4e-72, Method: Composition-based stats.
Identities = 92/416 (22%), Positives = 152/416 (36%), Gaps = 44/416 (10%)
Query: 89 GGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKI 148
G + AI+ A + + T N V + LG I
Sbjct: 43 GLVPHSAVAAIEAACQ-------AERYDTGALANAIATAGNSAIPLVKA------LGKVI 89
Query: 149 GSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVK 208
+ + + +S D T + + + + + +L L + L ++ +
Sbjct: 90 ATGVPEAERYVHLGATSQDAMDTGLVLQLRDAL-DLIEADLGKLADTLSQQALKHADTPL 148
Query: 209 IGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKT---LSFLAQGGTAVGTGLNTKP 265
+GRT LQ ATP+TLG + +G + + QR+ L F G+ G P
Sbjct: 149 VGRTWLQHATPVTLGMKLAGVLGALTRHRQRLQELRPRLLVLQFGGASGSLAALGSKAMP 208
Query: 266 GFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGS 325
+AE ++++ L P + D +VE + L +A SL K +DI L
Sbjct: 209 -----VAEALAEQLKLTLPEQPWHTQ----RDRLVEFASVLGLVAGSLGKFGRDISLLMQ 259
Query: 326 GPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV 385
E P + GSS MP K NP L +V G + + FA + E ++
Sbjct: 260 TEAGEVFEPSAP-GKGGSSTMPHKRNPVGAAVLIGAATRVPGLLSTL-FAAMPQEHERSL 317
Query: 386 FKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHEL--LTKSLMLVTA----LNP 439
L I + A EG++ + R+ LT+ L+L A L
Sbjct: 318 GLWHAEWETLPDICCLVSGALRQAQVIAEGMEVDAARMRRNLDLTQGLVLAEAVSIVLAQ 377
Query: 440 KIGYDAA---------SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHMLG 486
++G D A VA+ H + + E + L+ +E D + P H LG
Sbjct: 378 RLGRDRAHHLLEQCCQRAVAEQRHLRAVLGDEPQVS-AELSGEELDRLLDPAHYLG 432
>2X75-A nrPDB
Length = 431
Score = 260 bits (663), Expect = 1e-69, Method: Composition-based stats.
Identities = 76/346 (21%), Positives = 131/346 (37%), Gaps = 34/346 (9%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
+ +S D T + Q + + +L + L K+K + + + +GRTH A
Sbjct: 88 VHYGLTSTDVVDTALSF-VIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAE 146
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKE 278
P T G + + + +++ +QR + + G AVGT N P + + K
Sbjct: 147 PTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSG-AVGTFANIPPEIESYVC----KH 201
Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPE 338
G+ + D L +A SL K A +IR L E +
Sbjct: 202 LGIGTAPVSTQ---TLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEE-AFAK 257
Query: 339 NEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGS--QGQFELNVFKPVMIANLLN 396
+ GSS MP K NP +E +T + + G IT A E ++ +L
Sbjct: 258 GQKGSSAMPHKRNPIGSENITGISRVIRG---YITTAYENVPLWHERDISHSSAERIMLP 314
Query: 397 SIRLITDAAYSFRVHCV-------EGIKANEPRIHELLTKSLMLVTALNPKIGYDAA--- 446
+ + D A + + V + ++ N + L+ +L+ +N + + A
Sbjct: 315 DVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDK 374
Query: 447 -------SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485
S K ++ I ES VLT++E DE P+H L
Sbjct: 375 VQPKAMISWETKTPFRELIEQDESIT--SVLTKEELDECFDPKHHL 418
>1Q5N-A nrPDB
Length = 454
Score = 246 bits (628), Expect = 1e-65, Method: Composition-based stats.
Identities = 97/435 (22%), Positives = 172/435 (39%), Gaps = 46/435 (10%)
Query: 70 LVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSN 129
+V A L ++ A V G+ P+ + + Q A + A K+D T +G N
Sbjct: 30 MVEAEVALAQAQAQV-----GVIPQSAATVIQRAAKTAIDKID----FDALATATGLAGN 80
Query: 130 MNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPEL 189
+ V AI + ++ VH +S D T A LQ ++ L
Sbjct: 81 IAIPFVKQLTAIVKDADEDAARYVHWGA------TSQDILDT----ACILQCRDALAIVQ 130
Query: 190 TNLKNALE---AKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKT 246
++ E ++++ + H V +GRT LQ A P+TLG + + + + + R+
Sbjct: 131 NQVQQCYETALSQAQTYRHQVMMGRTWLQQALPITLGHKLARWASAFKRDLDRINAIKAR 190
Query: 247 LSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGAL 306
+ +AQ G AVG+ + + + + E +K+ L QTA D IVE + L
Sbjct: 191 V-LVAQLGGAVGSLASLQDQGSI-VVEAYAKQLKLG-QTACTWH---GERDRIVEIASVL 244
Query: 307 NTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVM 366
+ ++ K+A+D + E + GSS MP K NP ++ +V
Sbjct: 245 GIITGNVGKMARDWSLMMQTEIAEVFEPT-AKGRGGSSTMPHKRNPVAAASVLAAANRVP 303
Query: 367 GNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHEL 426
++I + + E ++ L I +T A + ++G++ N +H+
Sbjct: 304 ALMSSI-YQSMVQEHERSLGAWHAEWLSLPEIFQLTAGALERTLDVLKGMEVNAENMHQN 362
Query: 427 LTKSLMLV------TALNPKIGYDAA---------SKVAKNAHKKGITLKESALELGVLT 471
+ + L+ AL P +G A + VA+ H K I + +
Sbjct: 363 IECTHGLIMAEAVMMALAPHMGRLNAHHVVEAACKTAVAEQKHLKDI-ISQVDEVKQYFN 421
Query: 472 EKEFDEWVVPEHMLG 486
+ DE PE LG
Sbjct: 422 PSQLDEIFKPESYLG 436
>1TJ7-A nrPDB
Length = 457
Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats.
Identities = 75/326 (23%), Positives = 129/326 (39%), Gaps = 29/326 (8%)
Query: 146 GKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDH 205
GK+ K + +S ND T + + + +EL+ L++AL ++
Sbjct: 90 GKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTV-SELLTANRQLQSALVETAQNNQD 148
Query: 206 IVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTK 264
V G THLQ A P+T YV+ + R+ +LK L G G GT
Sbjct: 149 AVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEID 208
Query: 265 PGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLG 324
EQ++ G T N ++++ D ++E A L + A+D+ +
Sbjct: 209 R-------EQLAGWLGFASAT-RNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFN 260
Query: 325 SGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNA--AITFAGSQGQFE 382
+G G+ EL GSS+MP K NP E + C +V G +T G +
Sbjct: 261 TG-EAGFVELS-DRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYN 318
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
++ + L +++ D + ++GI+ PR E + G
Sbjct: 319 KDMQEDK--EGLFDALDTWLDCLH-MAALVLDGIQVKRPRCQEAAQQ------------G 363
Query: 443 YDAASKVAKNAHKKGITLKESALELG 468
Y A+++A KG+ +E+ +G
Sbjct: 364 YANATELADYLVAKGVPFREAHHIVG 389
>2PFM-A nrPDB
Length = 444
Score = 242 bits (617), Expect = 3e-64, Method: Composition-based stats.
Identities = 69/344 (20%), Positives = 131/344 (38%), Gaps = 30/344 (8%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
+ +S D T + Q ++ +L N + L K+KE + + +GRTH A
Sbjct: 99 VHYGLTSTDVVDTAL-SYILKQANEIILKDLENFVSILANKAKEHKYTIMMGRTHGVHAE 157
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKE 278
P T G + + ++++ ++R + T+ G AVGT N P + + E
Sbjct: 158 PTTFGLKLGLWYEEMKRNVERFKQAANTVRVGKLSG-AVGTYANIDPFVEKYVCE----- 211
Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPE 338
L + AP + L D L +A S+ K+A +IR L E +
Sbjct: 212 -NLGLEAAPISTQTL-QRDRHAHYMSTLALIATSIEKMAVEIRGLQKSETREVEE-AFAK 268
Query: 339 NEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSI 398
+ GSS MP K NP +E +T + + G + E ++ +L
Sbjct: 269 GQKGSSAMPHKRNPIGSENMTGLARVIRGYMMT-AYENVPLWHERDISHSSAERVILPDA 327
Query: 399 RLITDAAYSFRVHCVEGIKA-------NEPRIHELLTKSLMLVTALNPKIGYDAA----- 446
+ + + + V+ + N R + L+ +++T ++ + + A
Sbjct: 328 TIALNYMLNRFGNIVKNLTVYPENMKRNMTRTYGLIYSQRVMLTLIDKGMVREEAYDIVQ 387
Query: 447 -----SKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML 485
+ + K+ + E LT++E +E EH +
Sbjct: 388 PKAMEAWETQVQFKELVEADERITSK--LTQEEINECFNYEHHM 429
>1F1O-A nrPDB
Length = 431
Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats.
Identities = 66/342 (19%), Positives = 129/342 (37%), Gaps = 26/342 (7%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
+ +S D T + Q + L+ +L + ++ K+KE + V +GRTH A
Sbjct: 88 VHYGLTSTDVVDTAL-SYLLKQANDILLKDLERFVDIIKEKAKEHKYTVMMGRTHGVHAE 146
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKE 278
P T G + + + ++++ ++R + + G AVGT N P + + E++
Sbjct: 147 PTTFGLKLALWHEEMKRNLERFKQAKAGIEVGKISG-AVGTYANIDPFVEQYVCEKL--- 202
Query: 279 TGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPE 338
+ AP + L D + L +A S+ K A +IR L E +
Sbjct: 203 ---GLKAAPISTQTL-QRDRHADYMATLALIATSIEKFAVEIRGLQKSETREVEE-FFAK 257
Query: 339 NEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSI 398
+ GSS MP K NP +E +T + + G + E ++ +L
Sbjct: 258 GQKGSSAMPHKRNPIGSENMTGMARVIRGYMMT-AYENVPLWHERDISHSSAERIILPDA 316
Query: 399 RLITDAAYSFRVHCVEGIKA-------NEPRIHELLTKSLMLVTALNPKI----GYDAAS 447
+ + + + V+ + N R L+ +L+ ++ + YD
Sbjct: 317 TIALNYMLNRFSNIVKNLTVFPENMKRNMDRTLGLIYSQRVLLALIDTGLTREEAYDTVQ 376
Query: 448 KVAKNAHKKGITLKESALE----LGVLTEKEFDEWVVPEHML 485
A A +K + +E L+ ++ + + L
Sbjct: 377 PKAMEAWEKQVPFRELVEAEEKITSRLSPEKIADCFDYNYHL 418
>5EYT-A nrPDB
Length = 497
Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats.
Identities = 73/324 (22%), Positives = 139/324 (42%), Gaps = 28/324 (8%)
Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH 242
N L+P++ + L K+ ++ + RTHLQ A P T+G+ ++Q + ++ +
Sbjct: 140 NILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLER 199
Query: 243 SLK-TLSFLAQGGTAVGTGLNTKPGFD------VKIAEQISKETGLKFQTAPNKFEALAA 295
T+ F G AVGT + F +K+ E ++K++G +
Sbjct: 200 LKNHTIRFRGAKG-AVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVT--GQTYP 256
Query: 296 HDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP--ENEPGSSIMPGKVNPT 353
+E + AL+ + ++ KI DIR L S +HE+ P + GSS MP K NP
Sbjct: 257 RKVDIEITNALSNIGATVHKICTDIRLLSS-----FHEVEEPFETKQIGSSAMPYKRNPI 311
Query: 354 QNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCV 413
++E + +M + ++ S E ++ + +L L DA + +
Sbjct: 312 RSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIA 371
Query: 414 EGIKANEPRIHELLTKS---LMLVTALNPKIGYDAAS-------KVAKNAHKKGITLKES 463
EG+ P + E S ++V + K+ + A+ ++ K++H+ +K
Sbjct: 372 EGLIVY-PMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLK 430
Query: 464 ALELGVLTEKEFDEWVVPEHMLGP 487
L+ ++ + D + P H L P
Sbjct: 431 GLKNSLMDKLLNDYYFAPIHSLLP 454
>1C3C-A nrPDB
Length = 429
Score = 221 bits (562), Expect = 7e-58, Method: Composition-based stats.
Identities = 77/426 (18%), Positives = 151/426 (35%), Gaps = 50/426 (11%)
Query: 77 LKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVI 136
++ + E LG + +++ I+ A K+D + E
Sbjct: 25 VELAVTRAYEELGMIPKGVTERIRNNA------KIDVELFKKI--------------EEK 64
Query: 137 SNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNAL 196
+N + IGS + + +S+D T +A L+ L + L
Sbjct: 65 TNHDVVAFVEGIGSMIGEDSRFFHYGLTSSDVLDTANSLALVEA-GKILLESLKEFCDVL 123
Query: 197 EAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTA 256
+ + H IGRTH A P + G + G+ +++ +QR+ +++ +S+ G A
Sbjct: 124 WEVANRYKHTPTIGRTHGVHAEPTSFGLKVLGWYSEMKRNVQRLERAIEEVSYGKISG-A 182
Query: 257 VGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKI 316
VG N P + E+ GLK + + + D L +A + +I
Sbjct: 183 VGNYANVPPE----VEEKALSYLGLKPEPVSTQ---VVPRDRHAFYLSTLAIVAAGIERI 235
Query: 317 AQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAG 376
A +IR+L E + + GSS MP K NP E LT + ++M +
Sbjct: 236 AVEIRHLQRTEVLEVEEP-FRKGQRGSSAMPHKKNPITCERLTGLS-RMMRAYVDPSLEN 293
Query: 377 SQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRI-------HELLTK 429
E ++ + + + V +K NE R+ L+
Sbjct: 294 IALWHERDISHSSVERYVFPDATQTLYYMIVTATNVVRNMKVNEERMKKNIDLTKGLVFS 353
Query: 430 SLMLVTALNPKIGYDAA----------SKVAKNAHKKGITLKESALELGVLTEKEFDEWV 479
+L+ + + A + ++ + + E + ++T++E +E
Sbjct: 354 QRVLLKLIEKGLTRKEAYDIVQRNALKTWNSEKHFLEYLLEDEEVKK--LVTKEELEELF 411
Query: 480 VPEHML 485
+ L
Sbjct: 412 DISYYL 417
>2J91-A nrPDB
Length = 503
Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats.
Identities = 68/324 (20%), Positives = 116/324 (35%), Gaps = 16/324 (4%)
Query: 173 MHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQ 232
+ + L+P+L + + L +KE + +G TH Q A T+G+ ++Q
Sbjct: 141 TDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQD 200
Query: 233 VENGIQRVAHSLKTLSFLAQGGT--AVGTGLNTKPGFDVKIAEQISKETGLK--FQTAPN 288
+ +Q + L F GT + L G D K+ EQ+ K K F+ A
Sbjct: 201 LCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKV-EQLDKMVTEKAGFKRAFI 259
Query: 289 KFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPG 348
+E L +L S+ KI DIR L + E + + GSS MP
Sbjct: 260 ITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEM---EEPFEKQQIGSSAMPY 316
Query: 349 KVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSF 408
K NP ++E + +M S FE + L L D +
Sbjct: 317 KRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNT 376
Query: 409 RVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKK--------GITL 460
+ EG+ I + + L + N + A ++ H+K +
Sbjct: 377 LQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVV 436
Query: 461 KESALELGVLTEKEFDEWVVPEHM 484
K+ + ++ + D + P H
Sbjct: 437 KQEGGDNDLIERIQVDAYFSPIHS 460
>3C8T-A nrPDB
Length = 451
Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats.
Identities = 70/363 (19%), Positives = 131/363 (36%), Gaps = 35/363 (9%)
Query: 144 LGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELI---PELTNLKNALEAKS 200
L ++ + + + ++ D T A LQI++ L + +++ AL A +
Sbjct: 83 LVEQLSAHAGEAGKYLHWGATTQDIMDT----ATVLQIRDGLALISRRIESVRKALAALA 138
Query: 201 KEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKT---LSFLAQGGTAV 257
+ GRTHLQ A P+T G + + ++ + R+ + F GT
Sbjct: 139 RNHRDTPMAGRTHLQHALPVTFGYKAAVWLSAFDRHAARLEEISPRVLVVEFSGASGTLA 198
Query: 258 GTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIA 317
G + + ++++E L + +A DA+ E L ++ SL K+A
Sbjct: 199 SLGTR-----GLDVQRELARELNLGVPSITWH----SARDAVAETVQFLALVSGSLGKLA 249
Query: 318 QDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGS 377
DI + + E + + SS MP K NP E + +++ N+A
Sbjct: 250 MDISIMMTTELGEVAEPFV-RHRGASSTMPQKQNPVSCELI-LAGARIVRNHATSMLDAM 307
Query: 378 QGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVT-- 435
FE + + + + + G++ R+ E L S L+
Sbjct: 308 IHDFERATGPWHLEWSAVPEGFAVASGILYQAEFMLGGLQVFPDRMRENLDHSRGLIVAE 367
Query: 436 ----ALNPKIGYDAASKVAKNAHKKGITLKESALELGV--------LTEKEFDEWVVPEH 483
AL P G A + ++ + K E+ L E+ + P +
Sbjct: 368 AVMMALAPHTGRKEAHDIVYLGCRRAVEDKTGLFEVLRTMPEVAKPLGEEALRDLTDPRN 427
Query: 484 MLG 486
LG
Sbjct: 428 YLG 430
>1TJU-A nrPDB
Length = 474
Score = 213 bits (542), Expect = 2e-55, Method: Composition-based stats.
Identities = 75/370 (20%), Positives = 139/370 (37%), Gaps = 43/370 (11%)
Query: 104 DEVASG--KLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQ 161
+++ SG K+ + + VF + ANE R E++G G +
Sbjct: 63 EKILSGLEKISEEWSKGVFVVKQSDEDIHTANE---RRLKELIGDIAG--------KLHT 111
Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLT 221
+S ND T + + + L +K +E + E ++ G +HLQ A P+
Sbjct: 112 GRSRNDQVVTDLKLFMKNSLSIISTHLLQLIKTLVERAAIEI-DVILPGYSHLQKAQPIR 170
Query: 222 LGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIAEQISKETG 280
Q + + +R+ K ++ L G A+ G L+ E + E
Sbjct: 171 WSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALAGNPLDIDR-------EMLRSELE 223
Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENE 340
+ N +A++ D +VE L L K+A+D+ + S G+ L
Sbjct: 224 FASISL-NSMDAISERDFVVEFLSFATLLMIHLSKMAEDL-IIYSTSEFGFLTLS-DAFS 280
Query: 341 PGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFAGSQGQFELNVFKPVMIANLLNSI 398
GSS+MP K NP E + +V G A+I G + ++ + ++
Sbjct: 281 TGSSLMPQKKNPDSLELIRSKAGRVFGRLASILMVLKGLPSTYNKDLQEDK------EAV 334
Query: 399 RLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGI 458
+ D + G+ + E + K AL P++ A+ +A +KG+
Sbjct: 335 FDVVDTLTAVLQ-VATGVISTLQISKENMEK------ALTPEM---LATDLALYLVRKGV 384
Query: 459 TLKESALELG 468
+++ G
Sbjct: 385 PFRQAHTASG 394
>5V4L-A nrPDB
Length = 479
Score = 211 bits (538), Expect = 4e-55, Method: Composition-based stats.
Identities = 64/348 (18%), Positives = 127/348 (36%), Gaps = 21/348 (6%)
Query: 149 GSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVK 208
G+ + +S I + + L+P+L + + L +K++ +
Sbjct: 89 GTVAPEAAGIIHLGATSCYVTDNADLIFLRDGL-DILLPKLATVISRLANFAKQYRDLPT 147
Query: 209 IGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFD 268
+G TH Q A T+G+ + ++Q++ ++ + + L F GT GT + FD
Sbjct: 148 LGFTHFQPAQLTTVGKRATLWIQELLWDLRNLQRARDDLGFRGVKGT-TGTQASFLALFD 206
Query: 269 ------VKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRY 322
+ +++++ G + P + + G L++ ++ KIA DIR
Sbjct: 207 GDHAKVEALDKRVTELFGFPY-AYPV-TGQTYSRKIDADVLGPLSSFGATVHKIATDIRL 264
Query: 323 LGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFE 382
L + E +++ GSS M K NP + E + +M S E
Sbjct: 265 LANLKEI---EEPFEKDQIGSSAMAYKRNPMRCERACSLARHLMAIYQNTLMTSSVQWLE 321
Query: 383 LNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIG 442
+ + L D + + EG+ I +++ L + N +
Sbjct: 322 RTLDDSANRRVTIPEAFLTADILLTTLQNISEGLVVYPRVIGRRISQELPFMATENIIMA 381
Query: 443 YDAASKVAKNAHKK--------GITLKESALELGVLTEKEFDEWVVPE 482
A + H+K G +KE E ++ + DE+ P
Sbjct: 382 IVKAGGDRQECHEKIRVLSHQAGAVVKEEGGENDLIDRVKNDEYFKPI 429
>2E9F-A nrPDB
Length = 462
Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats.
Identities = 86/400 (21%), Positives = 156/400 (39%), Gaps = 45/400 (11%)
Query: 82 AIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAI 141
A + ++G L + +AI + D + FP ++ + + + + R
Sbjct: 43 ARMLHAVGLLSAEELEAILKGLDRIEEEIEAGTFP---WR-----EELEDVHMNLEARLT 94
Query: 142 EILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSK 201
E++G P + ++S ND T + + I L L + + K
Sbjct: 95 ELVGP--------PGGKLHTARSRNDQVATDLRLYLRGAIDELLALLLALRRVLVREAEK 146
Query: 202 EFDHI-VKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GT 259
D + V G THLQ A P+ L F Y + ++ R+ + + L+ G A+ GT
Sbjct: 147 HLDPLYVLPGYTHLQRAQPVLLAHWFLAYYEMLKRDAGRLEDAKERLNESPLGAAALAGT 206
Query: 260 GLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQD 319
G F ++E G K N +A+A+ D +E ALN L ++A++
Sbjct: 207 GFPIDRHF-------TARELGFK-APMRNSLDAVASRDFALEVLSALNIGMLHLSRMAEE 258
Query: 320 IRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFAGS 377
+ L S G+ E+ GSSIMP K NP E + +V+G + G
Sbjct: 259 L-ILYSTEEFGFVEVP-DAFATGSSIMPQKKNPDILELIRAKAGRVLGAFVGLSAVVKGL 316
Query: 378 QGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTAL 437
+ ++ + LL+++ D+ + G+K R+
Sbjct: 317 PLAYNKDLQEDK--EPLLDALATYRDSLRLLAA-LLPGLKWRRERMWRAAEG-------- 365
Query: 438 NPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDE 477
GY A+++A +KG+ +E+ +G L + +E
Sbjct: 366 ----GYTLATELADYLAEKGLPFREAHHVVGRLVRRLVEE 401
>1I0A-A nrPDB
Length = 466
Score = 201 bits (511), Expect = 5e-52, Method: Composition-based stats.
Identities = 79/370 (21%), Positives = 141/370 (38%), Gaps = 43/370 (11%)
Query: 104 DEVASG--KLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQ 161
+++ SG K+ + V TQS+ + I R E++G G Q
Sbjct: 61 EKILSGLEKISEESSKGVLVM---TQSDEDIQTAIERRLKELIGDIAGKLQ--------T 109
Query: 162 SQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLT 221
+S N+ T + + I L +K +E + E I+ G THLQ A P+
Sbjct: 110 GRSRNEQVVTDLKLLLKSSISVISTHLLQLIKTLVERAAIEI-DIIMPGYTHLQKALPIR 168
Query: 222 LGQEFSGYVQQVENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTKPGFDVKIAEQISKETG 280
Q + + +R+ K ++ L G G G L E + E
Sbjct: 169 WSQFLLSHAVALTRDSERLGEVKKRITVLPLGSGVLAGNPLEIDR-------ELLRSELD 221
Query: 281 LKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENE 340
+ T N +A++ D +VE L L K+A+D+ + S G+ L
Sbjct: 222 MTSITL-NSIDAISERDFVVELISVATLLMIHLSKLAEDL-IIFSTTEFGFVTLS-DAYS 278
Query: 341 PGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFAGSQGQFELNVFKPVMIANLLNSI 398
GSS++P K NP E + +V G AAI G F ++ + +L+ +
Sbjct: 279 TGSSLLPQKKNPDSLELIRSKAGRVFGRLAAILMVLKGIPSTFSKDLQEDK--EAVLDVV 336
Query: 399 RLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGI 458
+T A + ++ N+ + + LT L+ ++ +A +KG+
Sbjct: 337 DTLT-AVLQVATGVISTLQINKENMEKALTPELL-------------STDLALYLVRKGM 382
Query: 459 TLKESALELG 468
++++ G
Sbjct: 383 PIRQAQTASG 392
>5XNZ-A nrPDB
Length = 489
Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats.
Identities = 89/392 (22%), Positives = 145/392 (36%), Gaps = 34/392 (8%)
Query: 117 LVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIA 176
+ + G + AN V+ A L + + ++ +S D T +
Sbjct: 92 IDLLAVARGAR--ETANPVVGLVAA--LTAAVRRDDPAAAEYVHRGSTSQDVLDTGAMLV 147
Query: 177 ASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENG 236
A ++ + +L +AL A + + GRT A P T G + +G+++ V
Sbjct: 148 ARRALR-LIGDDLDRAADALAALAADHRDTPMAGRTLALHAVPTTFGLKAAGWLELVSEA 206
Query: 237 IQRVAHSLKTLSF--LAQGGTAVGT-GLNTKPGFDVKIAEQI----SKETGLKFQTAPNK 289
RVA L F GT G G T G + +++ + ETGL P
Sbjct: 207 AGRVARLRDGLPFSLGGAAGTLAGYFGDRTDRGDPAVLLDRLLDAYAAETGLARPVLPWH 266
Query: 290 FEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGK 349
+ + + L A +L KIA D++ L E + E SS MP K
Sbjct: 267 VL----RTPVADLAAVLAFTAGALGKIAVDVQSLARTEVAEVAEPAV-EGRGASSAMPHK 321
Query: 350 VNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIAN-LLNSIRLITDAAYSF 408
NP + + +QV +T + E + L +RL AA +
Sbjct: 322 RNPVLSTLIRSAALQVPALATGLTQC-LVSEDERSAGAWHAEWQPLRECLRLTGGAART- 379
Query: 409 RVHCVEGIKANEPRIHELLT------KSLMLVTALNPKIGYDAA----SKVAKNAHKKGI 458
V G++ + R+ L S + AL P +G AA ++ A A +G
Sbjct: 380 AVELAAGLEVDAARMRANLDLTDGRIVSESVAVALTPLLGRQAAKELLTRAAFTAGHEGR 439
Query: 459 TLKESALEL----GVLTEKEFDEWVVPEHMLG 486
TL E EL GVL ++ ++ + P G
Sbjct: 440 TLGEVLGELPELDGVLPKERWEALLDPARATG 471
>1AOS-A nrPDB
Length = 464
Score = 196 bits (499), Expect = 1e-50, Method: Composition-based stats.
Identities = 82/436 (18%), Positives = 152/436 (34%), Gaps = 55/436 (12%)
Query: 41 PADKYWGAQTQRSF----QNFKIGGARERMPLPL-VHAFGVLKKSAAIVNESLGGLDPKI 95
+ K WG + + + F A +R + V K+ + E G L
Sbjct: 4 ESQKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQG----SKAYSRGLEKAGLLTKAE 59
Query: 96 SKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHP 155
I D+VA + + F+ S + ANE R E++G G
Sbjct: 60 MDQILHGLDKVA-----EEWAQGTFKLNSNDEDIHTANE---RRLKELIGATAG------ 105
Query: 156 NNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQ 215
+ +S ND T + + + L L L + +++ ++ G THLQ
Sbjct: 106 --KLHTGRSRNDQVVTDLRLWMRQTC-STLSGLLWELIRTMVDRAEAERDVLFPGYTHLQ 162
Query: 216 DATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIAEQ 274
A P+ + + +R+ K ++ L G A+ G L E
Sbjct: 163 RAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDR-------EL 215
Query: 275 ISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHEL 334
+ E T N +A + D + E + L ++A+D+ L + +L
Sbjct: 216 LRAELNFGAITL-NSMDATSERDFVAEFLFWRSLCMTHLSRMAEDL-ILYCTKEFSFVQL 273
Query: 335 MLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAA--ITFAGSQGQFELNVFKPVMIA 392
GSS+MP K NP E + +V G A +T G + ++ +
Sbjct: 274 S-DAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDK--- 329
Query: 393 NLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKN 452
++ ++D + ++ I L + AL+P + A+ +A
Sbjct: 330 ---EAVFEVSDTMSAV-------LQVATGVISTLQIHQENMGQALSPDM---LATDLAYY 376
Query: 453 AHKKGITLKESALELG 468
+KG+ +++ G
Sbjct: 377 LVRKGMPFRQAHEASG 392
>5VKW-A nrPDB
Length = 482
Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats.
Identities = 59/312 (18%), Positives = 114/312 (36%), Gaps = 16/312 (5%)
Query: 183 NELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAH 242
+ LIP+L N+ + L + E+ + +G TH Q A T+G+ + ++Q++ ++ +
Sbjct: 126 DVLIPKLVNVIDRLSKFALEYKDLPVLGWTHFQPAQLTTVGKRATLWLQELLWDLRNMVR 185
Query: 243 SLKTLSFLAQGGTAVGTGLNTKPGF--DVKIAEQISKETG--LKFQTAPNKFEALAAHDA 298
+ + GT GT + F D E++ K L F +
Sbjct: 186 ARNDIGLRGVKGT-TGTQASFLSLFHGDHDKVEELDKRVVELLGFDIVYPVTGQTYSRKI 244
Query: 299 IVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEAL 358
++ L + + K A DIR L + E +++ GSS M K NP + E +
Sbjct: 245 DIDVLSPLASFGATAHKFATDIRLLANLKEI---EEPFEKSQIGSSAMAYKRNPMRCERV 301
Query: 359 TQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKA 418
+ + G S FE + + L S L D S ++ G+
Sbjct: 302 CSLARHLGGLFNDAVQTASVQWFERTLDDSAIRRISLPSAFLTVDILLSTMLNITSGLVV 361
Query: 419 NEPRIHELLTKSLMLVTALNPKIG--------YDAASKVAKNAHKKGITLKESALELGVL 470
I + L + N + D ++ +H+ +K+ + ++
Sbjct: 362 YPKVIERRINSELPFMATENIIMAMVEKGGSRQDCHEEIRVLSHQASAVVKQEGGDNDLI 421
Query: 471 TEKEFDEWVVPE 482
+ E+ P
Sbjct: 422 ERIKSTEYFKPI 433
>4EFC-A nrPDB
Length = 472
Score = 184 bits (468), Expect = 6e-47, Method: Composition-based stats.
Identities = 55/266 (20%), Positives = 100/266 (37%), Gaps = 14/266 (5%)
Query: 154 HPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTH 213
H + +S D T + + I +P L + +L +K ++ + + RTH
Sbjct: 128 HVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDW-DVPMLARTH 186
Query: 214 LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAE 273
Q A+P L +EF +++++ +++ T F G L P + +
Sbjct: 187 GQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGN-FNAHLVAYPSVNWRAFA 245
Query: 274 Q--ISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGY 331
++K GLK Q A + E +D + A L L + +D+ S G+
Sbjct: 246 DMFLAKYLGLKRQQATTQIE---NYDHLAALCDACARLHVILIDMCRDVWQYIS---MGF 299
Query: 332 HELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMI 391
+ + E E GSS MP KVNP E + + ++ ++
Sbjct: 300 FKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVL 359
Query: 392 ANLLNSIRLITDAAYSFRVHCVEGIK 417
NL I A +F +G++
Sbjct: 360 RNL---GVPIGHACVAFAS-ISQGLE 381
>2QGA-B nrPDB
Length = 465
Score = 184 bits (467), Expect = 8e-47, Method: Composition-based stats.
Identities = 61/342 (17%), Positives = 121/342 (35%), Gaps = 27/342 (7%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
C +N + T + + + +IP L + L+ + E+ H+ + RTH Q A+
Sbjct: 120 CTSEDINNVAYATCLKAC----LNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPAS 175
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVK-IAEQISK 277
T G+E + + ++ + + + F G + +K V I + K
Sbjct: 176 STTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKK 235
Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337
L + + + HD I E L +L + DI S +L +
Sbjct: 236 HFNLTYSIYCTQIQ---DHDYICELCDGLARANGTLIDLCVDIWLYISN---NLLKLKVK 289
Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQ-GQFELNVFKPVMIANLLN 396
E E GSS MP KVNP E + + + + + + ++ ++ N+ +
Sbjct: 290 EKEVGSSTMPHKVNPIDFENAEG-NLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGS 348
Query: 397 SIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLM-LVTALNPKIGYDA---ASKVAKN 452
S+ A S + I + + E L ++ L + + A + K
Sbjct: 349 SLAYCLIAYKSVLKG-LNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQ 407
Query: 453 AHKKGITLKESAL------ELGVLTEKEFDEWVV--PEHMLG 486
+G + + + + L + D+ + P G
Sbjct: 408 -FTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTG 448
>3BHG-A nrPDB
Length = 459
Score = 181 bits (458), Expect = 7e-46, Method: Composition-based stats.
Identities = 75/341 (21%), Positives = 130/341 (38%), Gaps = 28/341 (8%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
C +N + ++ A + IQ P + + ++ K+ + + RTH Q AT
Sbjct: 124 CTSEDINNLAYALMIKQAIAQVIQ----PTIAEIMGSITLLGKQHADVAMLSRTHGQPAT 179
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277
P T+G+E +V +++ Q++A L F G + P D K
Sbjct: 180 PTTMGKELVNFVARLKRPQQQLAEVLIPAKFNGAVGN-YNAHVAAYPEVDWRKHCANFVT 238
Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337
GL F + E HD I E S + + L QDI S GY +
Sbjct: 239 SLGLSFNAYTTQIE---PHDGIAEVSQIMVRINNILLDYTQDIW---SYISLGYFKQKTI 292
Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAG--SQGQFELNVFKPVMIANLL 395
E GSS MP KVNP E + N I FA +Q + + ++ ++ NL
Sbjct: 293 AEEVGSSTMPHKVNPIDFENAEGNLG--LSNALFIHFANKLTQSRMQRDLSDSTVLRNLG 350
Query: 396 NSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKS-LMLVTALNPKI-------GYDAAS 447
+ A +S + ++ N+ + + L+++ +L A+ + Y+
Sbjct: 351 VAFSYSLIAYHSVAKG-NDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPNAYEQLK 409
Query: 448 KVAKNAHKKGITLKESALELGVLTEKEFDEW--VVPEHMLG 486
++ + LK+ L + E+ E + PE G
Sbjct: 410 ELTRGQMIDAENLKKFIKTLS-IPEEAKAELMKLTPETYTG 449
>4MX2-A nrPDB
Length = 480
Score = 177 bits (448), Expect = 1e-44, Method: Composition-based stats.
Identities = 74/343 (21%), Positives = 127/343 (37%), Gaps = 26/343 (7%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
+ +S D T + + + + IP L L L++K E+ + + RTH Q A+
Sbjct: 144 IHFGLTSQDINNTSIPMLLRDALHHHYIPTLDQLIALLKSKLPEW-DVPMLARTHGQPAS 202
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAE-QIS 276
P L +EF +++++E + T F G L PG + E +S
Sbjct: 203 PTNLAKEFMVWIERLEEQRTMLLSIPNTGKFGGATGN-FNAHLCAYPGVNWLDFGELFLS 261
Query: 277 KETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELML 336
K GL+ Q + E +D + A L L +A+D+ S GY + +
Sbjct: 262 KYLGLRRQRYTTQIEH---YDNLAAICDACARLHTILMDLAKDVWQYIS---LGYFDQKV 315
Query: 337 PENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANL-- 394
E GSS MP KVNP E ++ + + ++ ++ NL
Sbjct: 316 RAGEVGSSAMPHKVNPIDFENAEGNLGMSNAVLGFLSAKLPISRLQRDLTDSTVLRNLGV 375
Query: 395 --------LNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAA 446
S+R D + ++ N + E + L P Y+A
Sbjct: 376 PLSHALIAFASLRRGIDKLLLNKDVIASDLEGNWAVVAEGIQTVLRREGYPKP---YEAL 432
Query: 447 SKVAK-NAHKKGITLKESALELGVLTEKEFDEWVV--PEHMLG 486
+ + NAH T+ +L +TE+ E + P +G
Sbjct: 433 KDLTRGNAHVTEETVHRFVQQLEGITEEVRQELLAITPFTYVG 475
>4EEI-A nrPDB
Length = 438
Score = 174 bits (441), Expect = 8e-44, Method: Composition-based stats.
Identities = 56/261 (21%), Positives = 106/261 (40%), Gaps = 13/261 (4%)
Query: 167 DTFPTVMHIAASLQIQNEL---IPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLG 223
T ++ A SLQI++ + I +L L ++L K++E I+ +GR+H A P++ G
Sbjct: 92 VTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFG 151
Query: 224 QEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKF 283
Q+F G + + ++ + K Q AVG + K A+ GL
Sbjct: 152 QKFLGAYVEFKRRLKDLKDFQKD-GLTVQFSGAVGNYCILTTEDEKKAAD----ILGLPV 206
Query: 284 QTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGS 343
+ + + D I + +A ++ ++A +IR+L +E + + GS
Sbjct: 207 EEVSTQ---VIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVYE-GFSKGQKGS 262
Query: 344 SIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITD 403
S MP K NP E LT + +++ ++ +I E ++ L I
Sbjct: 263 STMPHKKNPISTENLTGMA-RMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMV 321
Query: 404 AAYSFRVHCVEGIKANEPRIH 424
A + ++ + I
Sbjct: 322 YALRRMKNTIDNLVVQRDIIE 342
>1YIS-A nrPDB
Length = 478
Score = 174 bits (440), Expect = 9e-44, Method: Composition-based stats.
Identities = 57/283 (20%), Positives = 111/283 (39%), Gaps = 15/283 (5%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
+ +S IA I + ++ + + L A S + +V +GRTH Q A+
Sbjct: 102 IHLGATSCFVQDNADLIAYRDSI-DHILKRFATVIDRLAAFSLKNKEVVTVGRTHYQTAS 160
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQ-GGTAVGTGLNTKPGFDVKIAEQISK 277
+T+G+ + Q++ Q ++ + F G T T D E +
Sbjct: 161 LVTVGKRGVLWAQELLMAFQSLSEFRDKMRFRGIKGATGTQDSFLTLFAGDESKVEALD- 219
Query: 278 ETGLKFQTAPNKF---EALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHEL 334
E K N+F + + +L+ L + K+ DIR L + + EL
Sbjct: 220 ELVTKKANFSNRFLITGQTYSRQQDSQLVFSLSLLGAAAKKVCTDIRVLQA-----FGEL 274
Query: 335 MLP--ENEPGSSIMPGKVNPTQNEALTQVCVQVMGN-NAAITFAGSQGQFELNVFKPVMI 391
+ P +++ GSS MP K NP ++E + +++ A+T QG E +
Sbjct: 275 LEPFEKDQIGSSAMPYKKNPMKSERCCALSRKLINAPQEALTILADQG-LERTLDDSAGR 333
Query: 392 ANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLV 434
L+ + L +A + + EG+ + +++ + +
Sbjct: 334 RMLIPDVLLTAEALLTTLQNIFEGLSVQTDNVKKIVEDEIAFL 376
>2PTS-A nrPDB
Length = 462
Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats.
Identities = 59/339 (17%), Positives = 117/339 (34%), Gaps = 24/339 (7%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
C +N + ++ A I +P L + L+ + ++ I + RTH Q AT
Sbjct: 121 CTSEDINNLSHALMLKTARDEVI----LPYWRQLIDGLKDLAVQYRDIPLLSRTHGQPAT 176
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277
P T+G+E + ++E +++ G + P D + +E+
Sbjct: 177 PSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGN-YNAHIAAYPEVDWHQFSEEFVT 235
Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337
G+++ + E HD I E + L +D+ + + +
Sbjct: 236 SLGIQWNPYTTQIE---PHDYIAELFDCVARFNTILIDFDRDVWGYIA---LNHFKQKTI 289
Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNS 397
E GSS MP KVNP E + +++ ++ ++ NL
Sbjct: 290 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVG 349
Query: 398 IRLITDAAYSFRVHCVEGIKANEPR-IHELLTKSLMLVTALNPKI-------GYDAASKV 449
I A S + ++ N + EL +L + + Y+ ++
Sbjct: 350 IGYALIAYQSTLKGVSK-LEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKEL 408
Query: 450 AKNAHKKGITLKESALELGVLTEKEFDEW--VVPEHMLG 486
+ +K+ L L E+E + P + +G
Sbjct: 409 TRGKRVDAEGMKQFIDGLA-LPEEEKARLKAMTPANYIG 446
>4NSL-A nrPDB
Length = 470
Score = 171 bits (433), Expect = 7e-43, Method: Composition-based stats.
Identities = 60/339 (17%), Positives = 117/339 (34%), Gaps = 24/339 (7%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
C +N + ++ A I +P + NA++ + ++ I + RTH Q AT
Sbjct: 135 CTSEDINNLSHALMLKTARDEVI----LPYWRQVINAVKDLATQYRDIPLLSRTHGQPAT 190
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277
P TLG+E + ++E +++ G + P D + +E+
Sbjct: 191 PSTLGKEMANVAYRMERQFRQLNQVEILGKINGAVGN-YNAHIAAYPEVDWHQFSEEFVT 249
Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337
G+++ + E HD I E + L +D+ + + +
Sbjct: 250 SLGIQWNPYTTQIE---PHDYIAELFDCIARFNTILIDFDRDVWGYIA---LNHFKQKTI 303
Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNS 397
E GSS MP KVNP E + +++ ++ ++ NL
Sbjct: 304 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLHHLANKLPVSRWQRDLTDSTVLRNLGVG 363
Query: 398 IRLITDAAYSFRVHCVEGIKANEPR-IHELLTKSLMLVTALNPKI-------GYDAASKV 449
I A S + ++ N + EL +L + + Y+ ++
Sbjct: 364 IGYALIAYQSTLKGVSK-LEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKEL 422
Query: 450 AKNAHKKGITLKESALELGVLTEKEFDEW--VVPEHMLG 486
+ +K+ L L E E + P + +G
Sbjct: 423 TRGKRVDAEGMKQFIDSLA-LPEAEKTRLKAMTPANYIG 460
>5E3V-A nrPDB
Length = 380
Score = 167 bits (424), Expect = 7e-42, Method: Composition-based stats.
Identities = 45/237 (18%), Positives = 86/237 (36%), Gaps = 12/237 (5%)
Query: 159 CNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDAT 218
C +N + ++ A I +P + NA++ + ++ I + RTH Q AT
Sbjct: 135 CTSEDINNLSHALMLKTARDEVI----LPYWRQVINAVKDLATQYRDIPLLSRTHGQPAT 190
Query: 219 PLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDV-KIAEQISK 277
P TLG+E + ++E +++ G + P D + +E+
Sbjct: 191 PSTLGKEMANVAYRMERQFRQLNQVEILGKINGAVGN-YNAHIAAYPEVDWHQFSEEFVT 249
Query: 278 ETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLP 337
G+++ + E HD I E + L +D+ + + +
Sbjct: 250 SLGIQWNPYTTQIE---PHDYIAELFDCIARFNTILIDFDRDVWGYIA---LNHFKQKTI 303
Query: 338 ENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANL 394
E GSS MP KVNP E + +++ ++ ++ NL
Sbjct: 304 AGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLHHLANKLPVSRWQRDLTDSTVLRNL 360
>6IG5-A nrPDB
Length = 470
Score = 142 bits (357), Expect = 4e-34, Method: Composition-based stats.
Identities = 76/390 (19%), Positives = 143/390 (36%), Gaps = 46/390 (11%)
Query: 79 KSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISN 138
++ +V G L + + D +A D F +V ++ + + +
Sbjct: 43 RAHTMVLFRAGLLTEEQRDGLLAGLDSLAQDVADGSFGPLV--------TDEDVHAALER 94
Query: 139 RAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEA 198
I+ +G +G + +S ND + + ++ L + AL
Sbjct: 95 GLIDRVGPDLGGR-------LRAGRSRNDQVAALFRMWLRDAVRRVATGVLD-VVGALAE 146
Query: 199 KSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV- 257
++ + G+THLQ A P+ L + + + R+ K + G A+
Sbjct: 147 QAAAHPSAIMPGKTHLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALA 206
Query: 258 GTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIA 317
G+ L P + I+ + G A N +A AA D E + +A L ++A
Sbjct: 207 GSSLGLDP-------DAIAADLGFS-AAADNSVDATAARDFAAEAAFVFAMIAVDLSRLA 258
Query: 318 QDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAI--TFA 375
+DI + S GY L GSSIMP K NP E +++GN A + T
Sbjct: 259 EDI-IVWSSTEFGYVTLH-DSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLK 316
Query: 376 GSQGQFELNVFKPV-MIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLV 434
+ ++ + + + + + L+ A V + N R+ EL
Sbjct: 317 AQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGL----VASLTFNVQRMAELAPA----- 367
Query: 435 TALNPKIGYDAASKVAKNAHKKGITLKESA 464
GY A+ +A+ ++G+ + +
Sbjct: 368 -------GYTLATDLAEWLVRQGVPFRSAH 390
>1DOF-A nrPDB
Length = 403
Score = 131 bits (329), Expect = 7e-31, Method: Composition-based stats.
Identities = 62/321 (19%), Positives = 131/321 (40%), Gaps = 17/321 (5%)
Query: 157 NHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQD 216
+ + +SND T + + + + + + L + ++++ + +GRTH Q
Sbjct: 88 RYVHYGATSNDIIDTAWALLIRRALA-AVKEKARAVGDQLASMARKYKTLEMVGRTHGQW 146
Query: 217 ATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQIS 276
A P+TLG +F+ Y ++ +++A + + + A+ G AVGT + + +++ +++
Sbjct: 147 AEPITLGFKFANYYYELYIACRQLALAEEFIR--AKIGGAVGT-MASWGELGLEVRRRVA 203
Query: 277 KETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELML 336
+ GL + +A ++ + AL +A ++A +IR L E
Sbjct: 204 ERLGLPHHVITTQ---VAPRESFAVLASALALMAAVFERLAVEIRELSRPEIGEVVEGGG 260
Query: 337 PENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLN 396
+ MP K NPT +E + + V + F E ++ +
Sbjct: 261 GSS-----AMPHKANPTASERIVSLARYVRA-LTHVAFENVALWHERDLTNSANERVWIP 314
Query: 397 SIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSL--MLVTALNPKIGYDAASKVAKNAH 454
L D + + ++ + +E RI E L K+L +L ++ + AS+ A+
Sbjct: 315 EALLALDEILTSALRVLKNVYIDEERITENLQKALPYILTEFHMNRMIKEGASRA--EAY 372
Query: 455 KKGITLKESALELGVLTEKEF 475
KK +K E +
Sbjct: 373 KKAKEVKALTFEYQKWPVERL 393
>4NLE-A nrPDB
Length = 488
Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats.
Identities = 55/334 (16%), Positives = 112/334 (33%), Gaps = 21/334 (6%)
Query: 157 NHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQD 216
H ++ +S D V + ++ + + L ++ + +V GR+H
Sbjct: 108 EHVHKGMTSRDLTENVEQLQIRQSLELVFSHGVA-VVARLAERAVVYRDLVMAGRSHNVA 166
Query: 217 ATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAE--- 273
A TLG+ F+ ++ + R+ + G +GT + F + +
Sbjct: 167 AQATTLGKRFASAAEETLVALTRLRELIDRYPLRGVKG-PMGTAQDMLDLFGGDVGKLAD 225
Query: 274 ---QISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCG 330
++++ G + + AL +A IR +
Sbjct: 226 LERRVAEFLGFT--EVFTSVGQVYPRSLDHDVLSALVQFGAGPSSMAHTIRLMAGH---E 280
Query: 331 YHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVM 390
+ GSS MP K+N E + + V + G + E +VF V+
Sbjct: 281 LVTEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLRGYASMAAELAGAQWNEGDVFCSVV 340
Query: 391 IANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTK-------SLMLVTALNPKIGY 443
L D + ++ A I L + + +L+ A+ +G
Sbjct: 341 RRVALPDAFFAIDGQTETFLTVLDEFGAYPAVIQRELDRYLPFLATTRILMAAVRAGVGR 400
Query: 444 DAASKVAK-NAHKKGITLKESALELGVLTEKEFD 476
+AA +V K +A + ++E E ++ D
Sbjct: 401 EAAHEVIKEHAVAVALAMREQGREPDLIDRLAGD 434
>2FEL-A nrPDB
Length = 359
Score = 122 bits (305), Expect = 5e-28, Method: Composition-based stats.
Identities = 56/350 (16%), Positives = 108/350 (30%), Gaps = 38/350 (10%)
Query: 71 VHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNM 130
+ A + + A ++AI E F + G +
Sbjct: 30 IDAMIRFETALAQAEAEASIFADDEAEAIVSGLSE---------FAADMSALRHGVAKD- 79
Query: 131 NANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELT 190
E++ + + + +S D T + + + + L
Sbjct: 80 ------GVVVPELIRQMRAAVAGQAADKVHFGATSQDVIDTSLMLRLKMAA-EIIATRLG 132
Query: 191 NLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFL 250
+L + L + H G T +Q A +T+ +G++ +E + R+ + F
Sbjct: 133 HLIDTLGDLASRDGHKPLTGYTRMQAAIGITVADRAAGWIAPLERHLLRLETFAQN-GFA 191
Query: 251 AQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLA 310
Q G A GT + ++K GL + + D I E + L+ +
Sbjct: 192 LQFGGAAGTLEKLGDNAGA-VRADLAKRLGLADRP-----QWHNQRDGIAEFANLLSLVT 245
Query: 311 CSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCV----QVM 366
+L K QDI + + GSS MP K NP E L + Q+
Sbjct: 246 GTLGKFGQDIALMA-----EIGSEIRLSGGGGSSAMPHKQNPVNAETLVTLARFNAVQIS 300
Query: 367 GNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGI 416
+ ++ + E + ++ L + T + I
Sbjct: 301 ALHQSLV-----QEQERSGAGWMLEWLTLPQMVTATGTSLLVAERLAAQI 345
>6G3D-A nrPDB
Length = 508
Score = 110 bits (276), Expect = 1e-24, Method: Composition-based stats.
Identities = 59/327 (18%), Positives = 115/327 (35%), Gaps = 36/327 (11%)
Query: 157 NHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLK---NALEAKSKEFDHIVKIGRTH 213
+ +S ND + ++++L+ + + A+ K+ + V + T
Sbjct: 104 GKMHIGRSRNDLANAGKRMF----LRDQLLRTIEAVIGYREAVVHKAADHLDTVMVVYTQ 159
Query: 214 LQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAV-GTGLNTKPGFDVKIA 272
++A P+TLG + + + R ++ G A GTG
Sbjct: 160 RKEAQPITLGHYLMAISENLAKNLDRYRELYARINLCPLGAAATAGTG-------WPLNR 212
Query: 273 EQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYH 332
++ S G N E +A D + E + L ++A +I+ L S
Sbjct: 213 DRTSALLGFDGLVV-NSIEGVAGWDHVAEHAFVNAVFLSGLSRLASEIQ-LWSTDEYQVA 270
Query: 333 ELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNV----FKP 388
EL SSIMP K NP E + MG I + + +++ + +P
Sbjct: 271 ELDAS-FAGTSSIMPQKKNPDSLERSRKAAFAAMGPLVGILTSLNAIEYQYSAARVELEP 329
Query: 389 VMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALN------PKIG 442
I L+ + +T + + N+ R+ + ++ +T L I
Sbjct: 330 RSIDALIAATHAMTGVVRT--------LHPNKERMRQYAAENYSTMTDLTDMLVRRVGID 381
Query: 443 YDAASKVAKNAHKKGITLKESALELGV 469
Y A ++ + I A ++G+
Sbjct: 382 YREAHEIVAHVVITAIEKGIKANKIGL 408
>1GFN-A nrPDB
Length = 334
Score = 35.5 bits (80), Expect = 0.056, Method: Composition-based stats.
Identities = 19/85 (22%), Positives = 34/85 (40%), Gaps = 3/85 (3%)
Query: 211 RTHLQDATPLTLGQEFSGYVQQVENGIQRV---AHSLKTLSFLAQGGTAVGTGLNTKPGF 267
RT+LQ+A PL G++ + ++ + A+ +T + T
Sbjct: 190 RTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQ 249
Query: 268 DVKIAEQISKETGLKFQTAPNKFEA 292
DV + Q + GL+ A K +A
Sbjct: 250 DVLLVAQYQFDFGLRPSIAYTKSKA 274
>1H2B-A nrPDB
Length = 359
Score = 32.8 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 20/93 (21%), Positives = 35/93 (37%), Gaps = 7/93 (7%)
Query: 179 LQIQNELIPELTN---LKNALEAKSKEFDHIVKI-GRTH--LQDATPLTLGQEFSGYVQQ 232
L+I++ P L + + + + G H LQ P TLG E GY+++
Sbjct: 28 LRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPKLPYTLGHENVGYIEE 87
Query: 233 VENGIQRVAHSLKTLSFLAQG-GTAVGTGLNTK 264
V G++ + + A GT +
Sbjct: 88 VAEGVEGLEKGDPVILHPAVTDGTCLACRAGED 120
>4P1M-A nrPDB
Length = 123
Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats.
Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 12/81 (14%)
Query: 403 DAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKG----- 457
DA + ++ + R T+ L+ + ALN I Y+ A + AK
Sbjct: 39 DALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALN--ISYELAQEKAKTRDYAASMEQR 96
Query: 458 -----ITLKESALELGVLTEK 473
T++++ LE G +TEK
Sbjct: 97 IRMLQQTIEQALLEQGRITEK 117
>5M3L-D nrPDB
Length = 140
Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats.
Identities = 16/75 (21%), Positives = 23/75 (30%), Gaps = 5/75 (6%)
Query: 46 WGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADE 105
+GA +QR I + P L LK N L P+ +
Sbjct: 59 FGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERN-----LKPEFFDIFLKHLLH 113
Query: 106 VASGKLDDHFPLVVF 120
V +L HF +
Sbjct: 114 VLGDRLGTHFDFGAW 128
>4V93-B0 nrPDB
Length = 158
Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats.
Identities = 16/75 (21%), Positives = 23/75 (30%), Gaps = 5/75 (6%)
Query: 46 WGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADE 105
+GA +QR I + P L LK N L P+ +
Sbjct: 77 FGAHSQRVLSGLDITISMLDTPDMLAAQLAHLKVQHVERN-----LKPEFFDIFLKHLLH 131
Query: 106 VASGKLDDHFPLVVF 120
V +L HF +
Sbjct: 132 VLGDRLGTHFDFGAW 146
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.309 0.128 0.326
Lambda K H
0.267 0.0397 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,007,449
Number of Sequences: 36641
Number of extensions: 574590
Number of successful extensions: 1920
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1641
Number of HSP's gapped (non-prelim): 116
length of query: 488
length of database: 10,336,785
effective HSP length: 101
effective length of query: 387
effective length of database: 6,636,044
effective search space: 2568149028
effective search space used: 2568149028
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 61 (28.2 bits)