BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08319 (380 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3COS-A nrPDB 770 0.0 1E3E-A nrPDB 577 e-165 1MC5-A nrPDB 472 e-133 1EE2-A nrPDB 468 e-132 1HSZ-A nrPDB 463 e-131 1HSO-A nrPDB 458 e-129 1U3W-A nrPDB 457 e-129 1D1T-A nrPDB 439 e-123 4DLA-A nrPDB 417 e-117 4JJI-A nrPDB 414 e-116 1CDO-A nrPDB 412 e-116 1P0F-A nrPDB 409 e-114 4RQU-A nrPDB 390 e-109 5TNX-A nrPDB 190 1e-48 1F8F-A nrPDB 182 2e-46 3PII-A nrPDB 127 7e-30 4CPD-A nrPDB 117 7e-27 5YLN-A nrPDB 109 2e-24 3MEQ-A nrPDB 107 7e-24 2DFV-A nrPDB 104 5e-23 6N7L-A nrPDB 103 1e-22 4Z6K-A nrPDB 102 2e-22 3GFB-A nrPDB 102 4e-22 3S2F-A nrPDB 102 4e-22 1KEV-A nrPDB 100 1e-21 3FPL-A nrPDB 97 8e-21 1LLU-A nrPDB 97 9e-21 3FSR-A nrPDB 97 1e-20 1YKF-A nrPDB 94 7e-20 2DQ4-A nrPDB 92 3e-19 1H2B-A nrPDB 92 5e-19 1PL8-A nrPDB 90 1e-18 4UEJ-A nrPDB 90 2e-18 4OH1-A nrPDB 89 3e-18 3QE3-A nrPDB 87 8e-18 1E3J-A nrPDB 86 3e-17 6FG0-A nrPDB 86 3e-17 5VM2-A nrPDB 83 2e-16 2EER-A nrPDB 83 3e-16 2H6E-A nrPDB 79 3e-15 4EEZ-A nrPDB 77 8e-15 3FPC-A nrPDB 75 4e-14 3UOG-A nrPDB 74 8e-14 4GKV-A nrPDB 74 1e-13 5ENV-A nrPDB 73 2e-13 1R37-A nrPDB 72 3e-13 1UUF-A nrPDB 72 5e-13 3TWO-A nrPDB 72 6e-13 5K1S-A nrPDB 71 8e-13 3M6I-A nrPDB 70 2e-12 4EJ6-A nrPDB 69 4e-12 5YAT-A nrPDB 68 5e-12 4ILK-A nrPDB 68 7e-12 5KIA-A nrPDB 64 7e-11 5VKT-A nrPDB 64 1e-10 2OUI-A nrPDB 63 3e-10 1WLY-A nrPDB 62 3e-10 3WLE-A nrPDB 62 6e-10 4JLW-A nrPDB 60 1e-09 1KOL-A nrPDB 60 2e-09 6C49-A nrPDB 60 2e-09 3IP1-A nrPDB 59 3e-09 5H82-A nrPDB 55 4e-08 5H83-A nrPDB 55 7e-08 5FI5-A nrPDB 53 2e-07 6DKH-A nrPDB 51 8e-07 1YQX-A nrPDB 50 1e-06 2VCY-A nrPDB 50 2e-06 3JYN-A nrPDB 48 8e-06 5Z0C-A nrPDB 46 2e-05 4OAQ-A nrPDB 45 5e-05 1QOR-A nrPDB 45 7e-05 3SLK-A nrPDB 44 1e-04 2DPH-A nrPDB 43 2e-04 4DVJ-A nrPDB 42 3e-04 5A3V-A nrPDB 40 0.002 2CDC-A nrPDB 40 0.002 4RVS-A nrPDB 38 0.006 2OBY-A nrPDB 38 0.007 2VN8-A nrPDB 37 0.012 3B70-A nrPDB 37 0.014 3FBG-A nrPDB 37 0.015 1Q1N-A nrPDB 36 0.024 1YB5-A nrPDB 36 0.028 3TQH-A nrPDB 35 0.051 3HZZ-A nrPDB 35 0.066 5ILO-A nrPDB 34 0.083 3QWB-A nrPDB 34 0.10 4A27-A nrPDB 32 0.44 4IDE-A nrPDB 32 0.45 4J6F-A nrPDB 32 0.57 2VWH-A nrPDB 32 0.62 4IHE-A nrPDB 31 0.72 3QTD-A nrPDB 31 0.82 4EYE-A nrPDB 30 1.3 1MV8-A nrPDB 29 3.3 1JGT-A nrPDB 29 3.4 1ZOD-A nrPDB 28 4.4 3VV5-A nrPDB 28 5.1 3KIZ-A nrPDB 28 5.3 3BKX-A nrPDB 28 5.5 4EL1-A nrPDB 28 5.7 1E3W-A nrPDB 28 6.2 1MEK-A nrPDB 28 7.2 1V9L-A nrPDB 28 8.5 >3COS-A nrPDB Length = 381 Score = 770 bits (1989), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/380 (99%), Positives = 380/380 (100%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 61 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 241 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 301 AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 360 AAGSKGLT+FPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 361 ISEAFDLMNQGKSVRTILIF 380 ISEAFDLMNQGKS+RTILIF Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1E3E-A nrPDB Length = 376 Score = 577 bits (1486), Expect = e-165, Method: Compositional matrix adjust. Identities = 273/379 (72%), Positives = 323/379 (85%), Gaps = 3/379 (0%) Query: 2 GTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL 61 GT+GKVIKCKAAIAW+ G PLCIEE+EV+PPKA EVRIQ+IAT +C TD D K + L Sbjct: 1 GTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKAL 60 Query: 62 AFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKS 121 FPV++GHE AGIVES+GPGVTN KPGDKVIP +AP C++CK CLSPLTNLCGK+ N K Sbjct: 61 -FPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKY 119 Query: 122 PASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCG 181 P DQ+LMED+TSRFTCKG+ +YHF G S+FSQYTVVS+ NLA++DD+ANLERVCL+GCG Sbjct: 120 PTIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCG 179 Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 FS+GYGAAIN AKVTPGSTCAVFGLG VGLSA++GCK AGASRII IDIN EKF KAKAL Sbjct: 180 FSSGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKAL 239 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 GATDCLNPR+L KP+Q+VI ELT GGVD++LDCAG ++T+KAA+DCT GWGSCT +G Sbjct: 240 GATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVG-- 297 Query: 302 AGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 A +TI ++I+GR+INGTFFGGWKSVDS+P LV+DYKNKKF+LD LVTH LPF+ I Sbjct: 298 AKVDEMTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESI 357 Query: 362 SEAFDLMNQGKSVRTILIF 380 ++A DLM +GKS+RTIL F Sbjct: 358 NDAIDLMKEGKSIRTILTF 376 >1MC5-A nrPDB Length = 374 Score = 472 bits (1214), Expect = e-133, Method: Compositional matrix adjust. Identities = 231/373 (61%), Positives = 290/373 (77%), Gaps = 4/373 (1%) Query: 6 KVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPV 65 +VIKCKAA+AWEAGKPL IEE+EVAPPKAHEVRI+IIAT++CHTDA + FPV Sbjct: 4 EVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPV 63 Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 I+GHE AGIVES+G GVT +K GD VIPLY P C +CKFCL+P TNLC KI + Sbjct: 64 ILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQG---- 119 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTG 185 + LM D TSRFTCKGK + H+ GTSTFS+YTVV+DI++AKID A L++VCLLGCG STG Sbjct: 120 KGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTG 179 Query: 186 YGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245 YGAA+N AK+ PGS CAVFGLGGVGL+ +MGCK AGASRIIG+DIN +KF +AK GAT+ Sbjct: 180 YGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATE 239 Query: 246 CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 C+NP+D KPIQEV+IE+T GGVD++ +C G + M+AAL+ GWG +GVAA + Sbjct: 240 CINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGE 299 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF 365 + P +L+ GRT GT FGGWKSV+S+PKLV++Y +KK +D VTH L FD+I++AF Sbjct: 300 EIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAF 359 Query: 366 DLMNQGKSVRTIL 378 +LM+ GKS+RT++ Sbjct: 360 ELMHSGKSIRTVV 372 >1EE2-A nrPDB Length = 373 Score = 468 bits (1203), Expect = e-132, Method: Compositional matrix adjust. Identities = 230/378 (60%), Positives = 281/378 (74%), Gaps = 6/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C +D V+ Sbjct: 2 TAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVA-P 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI GHEAAGIVESIG GVT V+PGDKVIPL+ P C KC C P NLC + NL P Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLC--LKNLSMP 118 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 + M+D TSRFTC+GKP++HF GTSTFSQYTVV +I++AKID + LE+VCL+GCGF Sbjct: 119 ---RGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGF 175 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STGYG+A+ AKVT GSTCAVFGLGGVGLS +MGCKAAGA+RIIG+DIN +KF KAK +G Sbjct: 176 STGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVG 235 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 AT+C+NP+D KPIQEV+ E++ GGVDF+ + G +TM AAL C +G +GV Sbjct: 236 ATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPP 295 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 S+ L++ P L+ GRT G FGG+KS DS+PKLV D+ KKF LD L+TH LPF+KI+ Sbjct: 296 DSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKIN 355 Query: 363 EAFDLMNQGKSVRTILIF 380 E FDL+ GKS+RTIL F Sbjct: 356 EGFDLLRSGKSIRTILTF 373 >1HSZ-A nrPDB Length = 374 Score = 463 bits (1191), Expect = e-131, Method: Compositional matrix adjust. Identities = 228/378 (60%), Positives = 287/378 (75%), Gaps = 5/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IE+VEVAPPKA+EVRI+++A +C TD V+ Sbjct: 2 TAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-TP 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K ++L +P Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLK-NDLGNP 119 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 + ++D T RFTC+GKP++HF GTSTFSQYTVV + +AKID + LE+VCL+GCGF Sbjct: 120 ---RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 176 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STGYG+A+N AKVTPGSTCAVFGLGGVGLSAVMGCKAAGA+RII +DIN +KF KAK LG Sbjct: 177 STGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 236 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 AT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 237 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 296 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 S+ L+I P L+ GRT G +GG+KS + IPKLV D+ KKF+LDAL+TH LPF+KI+ Sbjct: 297 ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKIN 356 Query: 363 EAFDLMNQGKSVRTILIF 380 E FDL++ GKS+RT+L F Sbjct: 357 EGFDLLHSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 458 bits (1179), Expect = e-129, Method: Compositional matrix adjust. Identities = 228/379 (60%), Positives = 284/379 (74%), Gaps = 7/379 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C TD V+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TP 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI+GHEAAGIVES+G GVT VKPGDKVIPL P C KC+ C +P +N C LK+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYC-----LKND 115 Query: 123 ASDQQ-LMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCG 181 S+ Q ++D TSRFTC+ KP++HF G STFSQYTVV + +AKID + LE+VCL+GCG Sbjct: 116 VSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCG 175 Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 FSTGYG+A+N AKVTPGSTCAVFGLGGVGLSA+MGCKAAGA+RII +DIN +KF KAK L Sbjct: 176 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKEL 235 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 GAT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 236 GATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 295 Query: 302 AGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 S+ L++ P L+ GRT G GG+KS + +PKLV D+ KKF+LDAL+TH LPF+KI Sbjct: 296 PDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKI 355 Query: 362 SEAFDLMNQGKSVRTILIF 380 +E FDL++ GKS+RTIL+F Sbjct: 356 NEGFDLLHSGKSIRTILMF 374 >1U3W-A nrPDB Length = 374 Score = 457 bits (1176), Expect = e-129, Method: Compositional matrix adjust. Identities = 226/378 (59%), Positives = 283/378 (74%), Gaps = 5/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C +D V+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV-TP 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K ++L +P Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLK-NDLGNP 119 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 + ++D T RFTC GKP++HF G STFSQYTVV + +AKID + LE+VCL+GCGF Sbjct: 120 ---RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 176 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STGYG+A+ AKVTPGSTCAVFGLGGVGLS VMGCKAAGA+RII +DIN +KF KAK LG Sbjct: 177 STGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 236 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 AT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 237 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPP 296 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 S+ L+I P L+ GRT G FGG+KS +S+PKLV D+ KKF+LDAL+T+ LPF+KI+ Sbjct: 297 DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKIN 356 Query: 363 EAFDLMNQGKSVRTILIF 380 E FDL+ GKS+RT+L F Sbjct: 357 EGFDLLRSGKSIRTVLTF 374 >1D1T-A nrPDB Length = 373 Score = 439 bits (1128), Expect = e-123, Method: Compositional matrix adjust. Identities = 220/379 (58%), Positives = 272/379 (71%), Gaps = 6/379 (1%) Query: 2 GTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL 61 GT GKVIKCKAA+ WE +P IEE+EVAPPK EVRI+I+AT +C TD VI Sbjct: 1 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS- 59 Query: 62 AFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKS 121 FPVIVGHEA GIVESIG GVT VKPGDKVIPL+ P CR+C C +P NLC ++S Sbjct: 60 KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC-----IRS 114 Query: 122 PASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCG 181 + + ++ D T+RFTCKGKPV+HF TSTF++YTVV + ++AKIDD A E+VCL+GCG Sbjct: 115 DITGRGVLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCG 174 Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 FSTGYGAA+ KV PGSTC VFGLGGVGLS +MGCK+AGASRIIGID+N +KF KA A+ Sbjct: 175 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 234 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 GAT+C++P+D KPI EV+ E+T V + + G ETM AL +G+ +GV Sbjct: 235 GATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVP 294 Query: 302 AGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 +K LT P L GRT G FGG KS D +PKLVT++ KKF+LD L+TH LPF KI Sbjct: 295 PSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKI 354 Query: 362 SEAFDLMNQGKSVRTILIF 380 SE F+L+N G+S+RT+L F Sbjct: 355 SEGFELLNSGQSIRTVLTF 373 >4DLA-A nrPDB Length = 396 Score = 417 bits (1071), Expect = e-117, Method: Compositional matrix adjust. Identities = 202/376 (53%), Positives = 265/376 (70%), Gaps = 3/376 (0%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T+G+VI CKAA+AWE KPL IE+V+VAPP+A EVR++++ T+LCHTDA K Sbjct: 20 TQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGL 79 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 FP ++GHEAAGIVES+G GVT V+PGD VIP Y CR+CKFC S TNLCGK+ ++ Sbjct: 80 FPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKV---RAA 136 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +M D+ SRF+ GKP+YHF GTSTFSQYTVV D+++AKID A LE+VCLLGCG Sbjct: 137 TGVGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGV 196 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 TG GA N AKV PGS AVFGLG VGL+ G KAAGASRIIGIDI+S+KF +AK G Sbjct: 197 PTGLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFG 256 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 T+ +NP++ +PIQ+VI++LT GGVD++ +C G M++AL+C GWG+ +GVAA Sbjct: 257 VTEFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAA 316 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + ++ P +L+ GR GT FGG+KS +P LV Y K+ +D +TH + I+ Sbjct: 317 SGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADIN 376 Query: 363 EAFDLMNQGKSVRTIL 378 +AFDLM+ G +R +L Sbjct: 377 KAFDLMHDGDCLRVVL 392 >4JJI-A nrPDB Length = 378 Score = 414 bits (1063), Expect = e-116, Method: Compositional matrix adjust. Identities = 204/376 (54%), Positives = 264/376 (70%), Gaps = 3/376 (0%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T+G+VI CKAA+A+E KPL IE+V+VAPP+A EVRI+I+ T+LCHTDA K Sbjct: 2 TQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEGL 61 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 FP I+GHEAAGIVES+G GVT V+ GD VIP Y CR+CKFC S TNLCGK+ +S Sbjct: 62 FPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKV---RSA 118 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +M D+ SRF+ GKP+YHF GTSTFSQYTVV D+++AKID A L++VCLLGCG Sbjct: 119 TGVGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGV 178 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 TG GA N AKV PGS A+FGLG VGL+ G K AGASRIIGIDI+S+K+ AK G Sbjct: 179 PTGLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFG 238 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 + +NP+D KPIQEVI++LT GGVD++ +C G M+AAL+C GWG+ +GVAA Sbjct: 239 VNEFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAA 298 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + ++ P +L+ GR GT FGG+KS +P LV Y NK+ +D +TH L +I+ Sbjct: 299 SGQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEIN 358 Query: 363 EAFDLMNQGKSVRTIL 378 +AFDL+++G +R +L Sbjct: 359 KAFDLLHEGTCLRCVL 374 >1CDO-A nrPDB Length = 374 Score = 412 bits (1060), Expect = e-116, Method: Compositional matrix adjust. Identities = 206/376 (54%), Positives = 261/376 (69%), Gaps = 5/376 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+AWEA KPL IEE+EV P A+E+RI+IIAT +CHTD + Sbjct: 2 TVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKDG 61 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 FPV++GHE AGIVES+GPGVT +PG+KVIPL+ C +C+FC SP TN C K +SP Sbjct: 62 FPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESP 121 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +M K +RFTCKG+ V F GTSTFSQYTVV+ I +AKID A L+ VCLLGCG Sbjct: 122 ----DVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGV 177 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STG+GAA+N AKV PGSTCAVFGLG VGL+AVMGC +AGA RII +D+N +KF KAK G Sbjct: 178 STGFGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFG 237 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 ATD +NP D +PI +V+ ++T GGVDF+L+C G M+ AL+ GWG +G Sbjct: 238 ATDFVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVG-WT 296 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + P +LI GRT G+ FGG+K D +PK+V Y +KK LD +TH +P + ++ Sbjct: 297 DLHDVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVN 356 Query: 363 EAFDLMNQGKSVRTIL 378 +A DLM GK +RT+L Sbjct: 357 DAIDLMKHGKCIRTVL 372 >1P0F-A nrPDB Length = 373 Score = 409 bits (1050), Expect = e-114, Method: Compositional matrix adjust. Identities = 212/380 (55%), Positives = 276/380 (72%), Gaps = 7/380 (1%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60 M T GK I CKAA+AWE KPL +E + VAPPKAHEVRI+I+A+ +C +D++V+ Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 FPVI+GHEA G+VESIG GVT VKPGDKVIPL+ P C C+ C S +N C K Sbjct: 61 -KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEK----N 115 Query: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180 + LM D TSRFTC+GKP+Y+ GTSTF++YTVV+DI +AKID A LE CL+GC Sbjct: 116 DMGAKTGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGC 174 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 GF+TGYGAA+N AKVTPGSTCAVFGLGGVG SA++GCKAAGASRIIG+ + +KF KA Sbjct: 175 GFATGYGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIE 234 Query: 241 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 LGAT+CLNP+D KPI EVI E T GGVD+A++CAG ETM AL T G G +G+ Sbjct: 235 LGATECLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGL 294 Query: 301 AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 360 A+ ++ L + P L+ GR++ G+ FGG+K + + +LV DY KK N++ LV+ L D+ Sbjct: 295 ASPNERLPLDPLLLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQ 353 Query: 361 ISEAFDLMNQGKSVRTILIF 380 I++AF+L++ G+ VR+I+I+ Sbjct: 354 INKAFELLSSGQGVRSIMIY 373 >4RQU-A nrPDB Length = 375 Score = 390 bits (1003), Expect = e-109, Method: Compositional matrix adjust. Identities = 185/373 (49%), Positives = 253/373 (67%), Gaps = 3/373 (0%) Query: 6 KVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPV 65 ++I+CKAA+AWEAGKPL IEEVEVAPP+ HEVRI+I+ TSLCHTD ++K + FP Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 I GHEA GIVES+G GVT+++PGD V+P++ C +C+ C S +N+C L+ Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMC---DLLRINTER 118 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTG 185 ++ D SRF+ GKP+YHF GTSTFS+YTVV +AKI+ DA L++VC++ CG STG Sbjct: 119 GGMIHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTG 178 Query: 186 YGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245 GA +N AK G + A+FGLG VGL A G + AGASRIIG+D NS++F +AK G T+ Sbjct: 179 LGATLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTE 238 Query: 246 CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 C+NP+D KPIQ+VI E+T GGVD +++C G + M A +C GWG +GV + Sbjct: 239 CVNPKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDD 298 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF 365 P + RT+ GTFFG +K IP +V Y NK+ L+ +THT+PF +I++AF Sbjct: 299 AFKTHPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAF 358 Query: 366 DLMNQGKSVRTIL 378 D M +G+S+R I+ Sbjct: 359 DYMLKGESIRCII 371 >5TNX-A nrPDB Length = 383 Score = 190 bits (482), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 124/365 (33%), Positives = 186/365 (50%), Gaps = 17/365 (4%) Query: 19 GKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESI 78 G P IE + P+ EV ++++AT LCHTD V D + + P ++GHE AG+VE++ Sbjct: 27 GAPFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYP-VPLPAVLGHEGAGVVEAV 85 Query: 79 GPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138 GP V + GD V+ Y C C C C + L +D + +T+ Sbjct: 86 GPNVKTLAAGDHVVLTYGA-CGHCASCAGGHGAYCRQFFALNFGGADA---DGQTALRDA 141 Query: 139 KGKPVY-HFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTP 197 G+P++ HFF S+F+ Y + + N K+ +A LE + LGCG TG GA IN+ V Sbjct: 142 AGEPLHDHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRT 201 Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 GS+ A FG G VG+SAVM + AGA+ II +DI + A LGAT +N +++ + Sbjct: 202 GSSFASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VV 259 Query: 258 EVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA----GSKGLTIFPEE 313 + I E+T GGVD+AL+ G + +D GS +GV G+K Sbjct: 260 DAIREITGGGVDYALESTGLPAVLSQGIDA----LGSRGTMGVVGAPKLGTKAEFDVNSL 315 Query: 314 LIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKS 373 L+ G TI G G IP+LV + +F D LV P ++I++A + G + Sbjct: 316 LLGGHTIRGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLVKF-YPLEQINQAAADSSSGIT 374 Query: 374 VRTIL 378 ++ IL Sbjct: 375 LKPIL 379 >1F8F-A nrPDB Length = 371 Score = 182 bits (463), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 125/371 (33%), Positives = 189/371 (50%), Gaps = 15/371 (4%) Query: 12 AAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEA 71 AA+ G ++ +++ P+ EV ++++AT +CHTD V D K+ + P ++GHE Sbjct: 9 AAVTPCKGADFELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYP-VPLPAVLGHEG 67 Query: 72 AGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMED 131 +GI+E+IGP VT ++ GD V+ Y C KC C + C + +D + Sbjct: 68 SGIIEAIGPNVTELQVGDHVVLSYG-YCGKCTQCNTGNPAYCSEFFGRNFSGADSE---- 122 Query: 132 KTSRFTC---KGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 + C +G HFF S+F+ Y + + N K+ D +E + LGCG TG GA Sbjct: 123 -GNHALCTHDQGVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGA 181 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 IN KVTP S+ +G G VGLSA++ K GAS II +DI + AK LGAT +N Sbjct: 182 CINALKVTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVIN 241 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA-GSKGL 307 + P+ I E+T GGV+FAL+ G E +K +D G +G G+ Sbjct: 242 SKT-QDPV-AAIKEITDGGVNFALESTGSPEILKQGVDALGI-LGKIAVVGAPQLGTTAQ 298 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 + L+ G+TI G G IP+LV Y+ KF D LV FD+I++A Sbjct: 299 FDVNDLLLGGKTILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLVKF-YAFDEINQAAID 357 Query: 368 MNQGKSVRTIL 378 +G +++ I+ Sbjct: 358 SRKGITLKPII 368 >3PII-A nrPDB Length = 339 Score = 127 bits (320), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 110/367 (29%), Positives = 167/367 (45%), Gaps = 46/367 (12%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ + +PL I+EVE EV ++I A +CHTD + P+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E GIVE +GPGVT++K GD+V IP C C +CLS LC Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLC--------------- 106 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 K + ++ G +++Y + + KI D+ + E + C T Y A Sbjct: 107 EHQKNAGYSVDG----------GYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTYKA 156 Query: 189 -AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 + AK PG A++G+GG G AV KA G + ++ +DI EK AK LGA + Sbjct: 157 LKVTGAK--PGEWVAIYGIGGFGHVAVQYAKAMGLN-VVAVDIGDEKLELAKELGADLVV 213 Query: 248 NP--RDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 NP D K ++E + GGV A+ A ++A + G G+C +G+ Sbjct: 214 NPLKEDAAKFMKEKV-----GGVHAAVVTAVSKPAFQSAYNSIRRG-GACVLVGLPPEEM 267 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF 365 + IF + ++ G I G+ G K + + + K K + P +KI+E F Sbjct: 268 PIPIF-DTVLNGIKIIGSIVGTRKDLQEALQFAAEGKVKT------IIEVQPLEKINEVF 320 Query: 366 DLMNQGK 372 D M +G+ Sbjct: 321 DRMLKGQ 327 >4CPD-A nrPDB Length = 347 Score = 117 bits (294), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 98/377 (25%), Positives = 172/377 (45%), Gaps = 45/377 (11%) Query: 13 AIAWEAGKPLCIEEVEVAPPKAH--EVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHE 70 A+ +E + + ++EV AP H + +++ +C +D + K L V+ GHE Sbjct: 3 AVVFENKERVAVKEVN-APRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVL-GHE 60 Query: 71 AAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLME 130 G VE++G G+ +++PGD V+ + C C +C NLC + Sbjct: 61 FVGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGG------------- 107 Query: 131 DKTSRFTCKGKPVYHF---FGTSTFSQYTVV----SDINLAKIDDDANLERVCLLGCGFS 183 VY + FG +Q ++ S++NL K+ + + ER G S Sbjct: 108 ------------VYGYGPMFGNLQGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILS 155 Query: 184 TGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 T YG I ++ PG + AV G G VGL A+ + GAS+I+ ID E+ +A +LGA Sbjct: 156 TAYGGLIQ-GQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGA 214 Query: 244 TDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAG 303 ++ P++ V E G D L+ GG+ T+ AL+ G G + +GV Sbjct: 215 IPINAEQE--NPVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPG-GRVSAVGVDNA 271 Query: 304 SKGLTIFPEELIIGRTINGTFFGGWKSVD-SIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 FP L G + TF G +V I ++ + + + +V+H LP ++ Sbjct: 272 PS----FPFPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAP 327 Query: 363 EAFDLMNQGKSVRTILI 379 ++L ++ ++++ +L+ Sbjct: 328 RGYELFDRKEALKVLLV 344 >5YLN-A nrPDB Length = 356 Score = 109 bits (272), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 102/373 (27%), Positives = 166/373 (44%), Gaps = 38/373 (10%) Query: 15 AWEAGKPLCIEEVEVAPP---KAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEA 71 A+ KP V+V P K + ++I+ T++C TD +I I+GHE Sbjct: 7 AYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEG 66 Query: 72 AGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMED 131 GIVE +G GV+N K GDKV+ C KC +C + C ED Sbjct: 67 IGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHC----------------ED 110 Query: 132 KTSRFTCKGKPVYHFFGTSTFSQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAA 189 + G ++ ++Y V +D L +D + E + +L TGY Sbjct: 111 E-------GGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIG 163 Query: 190 INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNP 249 + KV PG + A+ G G VGL+A++ + +++I +D++ + A + GAT +N Sbjct: 164 VLKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNS 223 Query: 250 RDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALD-CTTAGWGSCTFIGVAAGSKGL 307 D K I+E I +LT G GVD A++ G + A D C T K + Sbjct: 224 SDPEKAIKE-IYDLTDGRGVDVAIEAVG----IPATFDFCQKIIGVDGTVANCGVHGKPV 278 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 ++L I R IN T G S ++ P+L+ ++ K + LVTH +I +A+++ Sbjct: 279 EFDLDKLWI-RNINVT--TGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEV 335 Query: 368 MNQGKSVRTILIF 380 ++ I + Sbjct: 336 FSKAADHHAIKVI 348 >3MEQ-A nrPDB Length = 365 Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 100/365 (27%), Positives = 157/365 (43%), Gaps = 40/365 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ GKPL I+EV + P ++++ I A+ +CHTD + + P I GH Sbjct: 27 KAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGH 86 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G V ++G GV +VK GD+V IP C C+ CL LC ++QL Sbjct: 87 EGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLC-----------EEQL 135 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY-G 187 + ++ G F++Y V + + + + + + C T Y G Sbjct: 136 ----NTGYSVNGG----------FAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVYKG 181 Query: 188 AAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 + + K PG + G+GG+G AV +A G + + +DI+ K A+ LGAT + Sbjct: 182 LKVTDTK--PGDWVVISGIGGLGHMAVQYARAMGLN-VAAVDIDDRKLDLARRLGATVTV 238 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 N + + P + E T GG L A + + AL G G+ + G+ G L Sbjct: 239 NAKTVADPAAYIRKE-TDGGAQGVLVTAVSPKAFEQALGMVARG-GTVSLNGLPPGDFPL 296 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 +IF ++ G T+ G+ G + D K K T + I+ FD Sbjct: 297 SIF-NMVLNGVTVRGSIVGTRLDLQESLDFAADGKVKA------TIQTGKLEDINAIFDD 349 Query: 368 MNQGK 372 M QG Sbjct: 350 MRQGN 354 >2DFV-A nrPDB Length = 347 Score = 104 bits (260), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 103/370 (27%), Positives = 167/370 (45%), Gaps = 58/370 (15%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESIGPGV 82 EV+V P EV I+++ATS+C TD + + + P I+GHE AG V IGPGV Sbjct: 20 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGPGV 79 Query: 83 TNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKP 142 ++ GD V +C KC C ++C N K Sbjct: 80 EGIEVGDYVSVETHIVCGKCYACRRGQYHVC---QNTK---------------------- 114 Query: 143 VYHFFGTST---FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTP-- 197 FG T F++Y VV N+ K E L G A++ P Sbjct: 115 ---IFGVDTDGVFAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNAVDTVLAGPIS 166 Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 G + + G G +GL + KA+GA +I + + + AK +GA +NP + + Sbjct: 167 GKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINP--FEEDVV 224 Query: 258 EVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELII 316 + ++++T G GVD L+ +G + ++ L T G + +G+ G +TI LII Sbjct: 225 KEVMDITDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGK--VTIDFNNLII 281 Query: 317 GRTINGTFFG-----GWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQ 370 + + T +G W++ ++ +L+ ++ K NLD ++TH FDK EAF+LM Sbjct: 282 FKAL--TIYGITGRHLWETWYTVSRLL---QSGKLNLDPIITHKYKGFDKYEEAFELMRA 336 Query: 371 GKSVRTILIF 380 GK+ + + + Sbjct: 337 GKTGKVVFML 346 >6N7L-A nrPDB Length = 353 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 102/371 (27%), Positives = 158/371 (42%), Gaps = 55/371 (14%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL-AFPVIVGH 69 KAA+ G+PL I+EV V P +EV ++++A +CHTD +D + P+I GH Sbjct: 15 KAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGH 74 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E GIV + GP VK GD V +P C C +C++ LC N Sbjct: 75 EGVGIVVACGPDAM-VKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQN---------- 123 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 ++ G F++Y + + + + N + + C T Y Sbjct: 124 -----GGYSVDG----------GFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-K 167 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + + PG A+ G+GG+G AV KA G + ID+ +K AK LGA +N Sbjct: 168 GLKETETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKLELAKKLGADLTVN 226 Query: 249 PRD------LHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 + LHK + GG+ AL A K +D G+ G+ Sbjct: 227 AKTTDPGTYLHKEV---------GGMHGALITAVSPIAFKQGIDVLRRK-GTIALNGLPP 276 Query: 303 GSKGLTIFPEELIIGR-TINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 GS L IF E ++ R T+ G+ G K + D+ N+ + A VT + + I Sbjct: 277 GSFELPIF--ETVLKRITVRGSIVGTRKDLQE----ALDFANEGL-VKATVT-SAKLEDI 328 Query: 362 SEAFDLMNQGK 372 ++ FD M +G+ Sbjct: 329 NDVFDKMKKGQ 339 >4Z6K-A nrPDB Length = 346 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 105/373 (28%), Positives = 173/373 (46%), Gaps = 44/373 (11%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ E G+ L IEEV++ P A E+ +++ A+ +CHTD ++ + + P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G++ ++G GVT+VK GD+V + C C CL LC N Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQN---------- 111 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDA--NLERVCLLGCGFSTGY 186 S ++ G +F++Y V+++ N I ++ ++E +L G + Sbjct: 112 -----SGYSVNG----------SFAEY-VLANANYVGIIPESVDSIEIAPVLCAGVTVYK 155 Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 G + + K PG + G+GG+G AV A G + + +DI+ +K AK LGA Sbjct: 156 GLKMTDTK--PGDWVVISGIGGLGHMAVQYAIAMGLN-VAAVDIDDDKLAFAKKLGAKVT 212 Query: 247 LNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 +N ++ P + + E+ GG AL A ++ AL G G+ G+ G Sbjct: 213 VNAKNT-DPAEYLQKEI--GGAHGALVTAVSAKAFDQALSMLRRG-GTLVCNGLPPGDFP 268 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 ++IF + ++ G TI G+ G + + K K A VT P + I++ F+ Sbjct: 269 VSIF-DTVLNGITIRGSIVGTRLDLQESLDMAAAGKVK-----ATVTAE-PLENINDIFE 321 Query: 367 LMNQGKSVRTILI 379 M QGK I+I Sbjct: 322 RMRQGKIEGRIVI 334 >3GFB-A nrPDB Length = 350 Score = 102 bits (253), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 97/364 (26%), Positives = 165/364 (45%), Gaps = 50/364 (13%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESIGPGV 82 EV+V P EV I+++ATS+C TD + + + P I+GHE AG V +GPGV Sbjct: 21 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVGPGV 80 Query: 83 TNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRF-TCKGK 141 +++ GD + +C KC C K +R+ C+ Sbjct: 81 EDLQVGDYISVETHIVCGKCYAC--------------------------KHNRYHVCQNT 114 Query: 142 PVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTP--GS 199 ++ F+ Y +V N K D E L G A++ P G Sbjct: 115 KIFGVDMDGVFAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGNAVDTVLAGPIAGR 169 Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEV 259 + + G G +GL + KA+GA +I + + + AK +GA +NP + P++ Sbjct: 170 STLITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFE-EDPVK-F 227 Query: 260 IIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGR 318 ++++T G GV+ L+ +G + ++ L T G G + +G+ + +TI LII + Sbjct: 228 VMDITDGAGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLF--PREVTIDFNNLIIFK 284 Query: 319 TINGTFFGG---WKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQGKSV 374 + G W++ ++ L+ ++ K NLD ++TH FDK EAF+LM GK+ Sbjct: 285 ALEVHGITGRHLWETWYTVSSLI---QSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTG 341 Query: 375 RTIL 378 + + Sbjct: 342 KVVF 345 >3S2F-A nrPDB Length = 340 Score = 102 bits (253), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 103/374 (27%), Positives = 160/374 (42%), Gaps = 43/374 (11%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ G PL I+EV V P +V+++I A+ +CHTD D + P I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G V ++G GV+ VK GD+V +P C C+ CL LC K N Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQN---------- 113 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY-G 187 + ++ G + +Y V + + D + + C T Y G Sbjct: 114 -----TGYSVNGG----------YGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVYKG 158 Query: 188 AAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 + + + PG + G+GG+G AV +A G R+ +DI+ K A+ LGA + Sbjct: 159 LKVTDTR--PGQWVVISGIGGLGHVAVQYARAMGL-RVAAVDIDDAKLNLARRLGAEVAV 215 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 N RD P + E+ GG L A + A+ G G+ G+ G G Sbjct: 216 NARDT-DPAAWLQKEI--GGAHGVLVTAVSPKAFSQAIGMVRRG-GTIALNGLPPGDFGT 271 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 IF + ++ G TI G+ G S + D+ ++ A V+ T D +++ F Sbjct: 272 PIF-DVVLKGITIRGSIVG----TRSDLQESLDFAAHG-DVKATVS-TAKLDDVNDVFGR 324 Query: 368 MNQGK-SVRTILIF 380 + +GK R +L F Sbjct: 325 LREGKVEGRVVLDF 338 >1KEV-A nrPDB Length = 351 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 102/343 (29%), Positives = 150/343 (43%), Gaps = 37/343 (10%) Query: 34 AHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVI- 92 +++ ++ +A S C +D + G +I+GHEA G V +G V + KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIV 83 Query: 93 PLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTF 152 P P R + + G ++ K + F F Sbjct: 84 PCTTPDWRSLEVQAGFQQHSNGMLAGWK-----------------------FSNFKDGVF 120 Query: 153 SQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVG 210 +Y V +D+NLA + D LE ++ +TG+ A A + GS+ V G+G VG Sbjct: 121 GEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVVVIGIGAVG 179 Query: 211 LSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVD 269 L + G K GA RIIG+ AK GATD LN ++ H I + +++LT G GVD Sbjct: 180 LMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGH--IVDQVMKLTNGKGVD 237 Query: 270 FALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG---RTINGTFFG 326 + GGSET+ A+ G G + I L I E G +TI G Sbjct: 238 RVIMAGGGSETLSQAVSMVKPG-GIISNINYHGSGDALLIPRVEWGCGMAHKTIKGGLCP 296 Query: 327 GWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLM 368 G + + + + Y + +L LVTH FD I EA LM Sbjct: 297 GGRLRAEMLRDMVVY--NRVDLSKLVTHVYHGFDHIEEALLLM 337 >3FPL-A nrPDB Length = 351 Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 101/343 (29%), Positives = 151/343 (44%), Gaps = 37/343 (10%) Query: 34 AHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVI- 92 +++ ++ +A S C +D + G +I+GHEA G V +G V + KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIV 83 Query: 93 PLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTF 152 P P R + + G ++ K + F F Sbjct: 84 PCTTPDWRSLEVQAGFQQHSNGMLAGWK-----------------------FSNFKDGVF 120 Query: 153 SQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVG 210 +Y V +D+NLA + D LE ++ +TG+ A A + G+T AV G+G VG Sbjct: 121 GEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAVLGIGPVG 179 Query: 211 LSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVD 269 L AV G K GA RII + AK GATD +N +D PI+ I+ LT+G GVD Sbjct: 180 LMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEGKGVD 237 Query: 270 FALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG---RTINGTFFG 326 A+ G ++ M A+ G G+ + + L + E G +TI G Sbjct: 238 AAIIAGGNADIMATAVKIVKPG-GTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGLCP 296 Query: 327 GWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLM 368 G + + + + Y + +L LVTH FD I EA LM Sbjct: 297 GGRLRAEMLRDMVVY--NRVDLSKLVTHVYHGFDHIEEALLLM 337 >1LLU-A nrPDB Length = 342 Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 98/365 (26%), Positives = 152/365 (41%), Gaps = 42/365 (11%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ G PL IEEV+V P +V ++I A+ +CHTD + + P I GH Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGH 67 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G V ++G GVT VK GD+V IP C C+ CL+ LC N Sbjct: 68 EGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQN---------- 117 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY-G 187 + ++ G +++Y + + + + + + C T Y G Sbjct: 118 -----TGYSVNGG----------YAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVYKG 162 Query: 188 AAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 NA+ PG A+ G+GG+G AV +A G + IDI+ K A+ LGA+ + Sbjct: 163 LKQTNAR--PGQWVAISGIGGLGHVAVQYARAMGL-HVAAIDIDDAKLELARKLGASLTV 219 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 N R P++ I+ GG L A + A+ G G+ +G+ G Sbjct: 220 NARQ-EDPVEA--IQRDIGGAHGVLVTAVSNSAFGQAIGMARRG-GTIALVGLPPGDFPT 275 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 IF + ++ G I G+ G + D+ + L H D I++ D Sbjct: 276 PIF-DVVLKGLHIAGSIVGTRADLQE----ALDFAGE--GLVKATIHPGKLDDINQILDQ 328 Query: 368 MNQGK 372 M G+ Sbjct: 329 MRAGQ 333 >3FSR-A nrPDB Length = 352 Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 103/350 (29%), Positives = 152/350 (43%), Gaps = 35/350 (10%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNV 85 E E P + ++ +A + C +D + G +I+GHEA G V +G V + Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 86 KPGDKVI-PLYAPLCRKCKFCLSPLTNLCGKISNLK-SPASDQQLMEDKTSRFTCKGKPV 143 KPGD+V+ P P R + + G ++ K S D E Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGE------------- 122 Query: 144 YHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAV 203 FF + +D+NLA + + LE ++ +TG+ A A + GS+ V Sbjct: 123 --FFHVND-------ADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVV 172 Query: 204 FGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIEL 263 G+G VGL + G K GA RIIG+ AK GATD LN ++ H I + +++L Sbjct: 173 IGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGH--IVDQVMKL 230 Query: 264 TKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG---RT 319 T G GVD + GGSET+ A+ G G + I L I E G +T Sbjct: 231 TNGKGVDRVIMAGGGSETLSQAVSMVKPG-GIISNINYHGSGDALLIPRVEWGCGMAHKT 289 Query: 320 INGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLM 368 I G G + + +L+ K+ + LVTH FD I +AF LM Sbjct: 290 IKGGLCPGGRL--RMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >1YKF-A nrPDB Length = 352 Score = 94.4 bits (233), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 102/352 (28%), Positives = 153/352 (43%), Gaps = 35/352 (9%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNV 85 E E P + ++ +A + C +D + G +I+GHEA G V +G V + Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 86 KPGDKVI-PLYAPLCRKCKFCLSPLTNLCGKISNLK-SPASDQQLMEDKTSRFTCKGKPV 143 KPGD+V+ P P R + + G ++ K S D E Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGE------------- 122 Query: 144 YHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAV 203 FF + +D+NLA + + LE ++ +TG+ A A + G+T AV Sbjct: 123 --FFHVND-------ADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAV 172 Query: 204 FGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIEL 263 G+G VGL AV G K GA RII + AK GATD +N +D PI+ I+ L Sbjct: 173 LGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNL 230 Query: 264 TKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG---RT 319 T+G GVD A+ G ++ M A+ G G+ + + L + E G +T Sbjct: 231 TEGKGVDAAIIAGGNADIMATAVKIVKPG-GTIANVNYFGEGEVLPVPRLEWGCGMAHKT 289 Query: 320 INGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQ 370 I G G + + +L+ K+ + LVTH FD I +AF LM Sbjct: 290 IKGGLCPGGRL--RMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >2DQ4-A nrPDB Length = 343 Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 99/388 (25%), Positives = 163/388 (42%), Gaps = 66/388 (17%) Query: 8 IKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVI--DSKFEG-LAFP 64 ++ A +A E G L + + V P E+ +++ A S+C TD + D+ G + P Sbjct: 1 MRALAKLAPEEG--LTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPP 58 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 ++ GHE +G+VE++GPGV + GD V +C C C + ++C + Sbjct: 59 LVTGHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVC---------LN 109 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFST 184 Q L D+ F++Y VV N D E +L Sbjct: 110 TQILGVDR----------------DGGFAEYVVVPAENAWVNPKDLPFEVAAIL-----E 148 Query: 185 GYGAAINNAKV---TPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 +G A++ G + + G G +GL A M +A+GA I+ D N + A+ Sbjct: 149 PFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY 208 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 A +NP L + + EV+ +T GV+ L+ +G + L G G +G+ Sbjct: 209 -ADRLVNP--LEEDLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIPG-GEARILGIP 264 Query: 302 AGS-----------KGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDA 350 + +G+T F I GR + T+ G V S + +L Sbjct: 265 SDPIRFDLAGELVMRGITAFG---IAGRRLWQTWMQGTALVYS----------GRVDLSP 311 Query: 351 LVTHTLPFDKISEAFDLMNQGKSVRTIL 378 L+TH LP + EAF L+ G++V+ IL Sbjct: 312 LLTHRLPLSRYREAFGLLASGQAVKVIL 339 >1H2B-A nrPDB Length = 359 Score = 91.7 bits (226), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 105/382 (27%), Positives = 170/382 (44%), Gaps = 45/382 (11%) Query: 7 VIKCKAAIAWEAGKPLCIEEVEVAPPKAH-EVRIQIIATSLCHTDATVIDSKFEGL---A 62 V + KAA E KPL IE+V+ + +V ++I +CHTD ++ + L Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 P +GHE G +E + GV ++ GD VI A C C + C NL+ P Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHC---ENLEFP 129 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 G F TS S + DI+ K+ +E L G Sbjct: 130 G------------LNIDGG-FAEFMRTSHRSVIKLPKDISREKL-----VEMAPLADAGI 171 Query: 183 STGYGAAINNAK-VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 T Y A A+ + PG+ A+ G+GG+G AV K + +I +D+ EK A+ L Sbjct: 172 -TAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERL 230 Query: 242 GATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 GA ++ R P+++V +ELT+G GV+ A+D G +A +D T G + + Sbjct: 231 GADHVVDAR--RDPVKQV-MELTRGRGVNVAMDFVGS----QATVDYTPYLLGRMGRL-I 282 Query: 301 AAGSKGLTIFPEELIIGRTIN--GTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPF 358 G G FP +I ++ G+ G + + +LVT K ++ + H L Sbjct: 283 IVGYGGELRFPTIRVISSEVSFEGSLVGNYVELH---ELVTLALQGKVRVEVDI-HKL-- 336 Query: 359 DKISEAFDLMNQGKSV-RTILI 379 D+I++ + + +G+ + R +LI Sbjct: 337 DEINDVLERLEKGEVLGRAVLI 358 >1PL8-A nrPDB Length = 356 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 92/370 (24%), Positives = 165/370 (44%), Gaps = 54/370 (14%) Query: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESI 78 L +E + P +EV +++ + +C +D + G + P+++GHEA+G VE + Sbjct: 19 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 78 Query: 79 GPGVTNVKPGDKV-IPLYAP-----LCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDK 132 G V ++KPGD+V I AP C+ ++ LSP C +P D L Sbjct: 79 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA------TPPDDGNL---- 128 Query: 133 TSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINN 192 C+ F+ + Y K+ D+ E L+ S G A Sbjct: 129 -----CR------FYKHNAAFCY---------KLPDNVTFEEGALIE-PLSVGIHAC-RR 166 Query: 193 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL 252 VT G V G G +G+ ++ KA GA++++ D+++ + KAK +GA L + Sbjct: 167 GGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQ---I 223 Query: 253 HKPIQEVIIELTKGGV----DFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 K + I +G + + ++C G +++A + T +G T + V GS+ +T Sbjct: 224 SKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGG---TLVLVGLGSE-MT 279 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 P R ++ G ++ ++ P ++ +K N+ LVTH P +K EAF+ Sbjct: 280 TVPLLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETF 337 Query: 369 NQGKSVRTIL 378 +G ++ +L Sbjct: 338 KKGLGLKIML 347 >4UEJ-A nrPDB Length = 346 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 93/364 (25%), Positives = 155/364 (42%), Gaps = 65/364 (17%) Query: 36 EVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV--IP 93 EVR++I ++ LC +D I K +P+ +GHE +G ++++G GV ++ PGD V +P Sbjct: 27 EVRVKIASSGLCGSDLPRI-FKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVP 85 Query: 94 LYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST-- 151 L C C CL + C K Y F G+ Sbjct: 86 LLP--CFTCPECLKGFYSQCAK----------------------------YDFIGSRRDG 115 Query: 152 -FSQYTVVSDINL------AKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF 204 F++Y VV N+ I+D A +E + + F G N + Sbjct: 116 GFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKN--------VIII 167 Query: 205 GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKP-IQEVIIEL 263 G G +GL A+ A GA + IDI+SEK AK+ GA N ++ P +Q V+ EL Sbjct: 168 GAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 Query: 264 TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT------IFPEEL-II 316 L+ AG +T++ A++ +G LT I +EL +I Sbjct: 228 RFN--QLILETAGVPQTVELAVE-IAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVI 284 Query: 317 GRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF-DLMNQGKSVR 375 G +N + + ++ +L+T+ +K +L+ L+ H F+ ++A D+ + Sbjct: 285 GSWMNYSSPWPGQEWETASRLLTE---RKLSLEPLIAHRGSFESFAQAVRDIARNAMPGK 341 Query: 376 TILI 379 +LI Sbjct: 342 VLLI 345 >4OH1-A nrPDB Length = 351 Score = 89.4 bits (220), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 83/328 (25%), Positives = 132/328 (40%), Gaps = 53/328 (16%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA------FPVIVGHEAAGIVESIG 79 E + PK E+RI+++ S+C +D ++ + P+ GHE +G+++ +G Sbjct: 25 EAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVIDKVG 84 Query: 80 PGVTNV--KPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFT 137 + K G KV+ YA C C+ C NLC + Sbjct: 85 STAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMG-------------------- 124 Query: 138 CKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCL---LGCGFSTGYGAAINNAK 194 + + FS+Y V + I DDA+L+ L L S+ AK Sbjct: 125 ---------YRMNGFSEYAVYHMSQIFPIPDDADLKDYALVEPLTVALSSA-----EQAK 170 Query: 195 VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHK 254 ++ G + A+ G GG+G+ V + AGAS I DI EK A GA LN + + Sbjct: 171 ISYGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--E 228 Query: 255 PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL 314 + E IEL G D L+ G + K L A G + + L + + Sbjct: 229 GVAERAIELAGGRYDCVLEGTGATAAAKLGLQL-LARDGDAVYFAMYGKDPILPVNLQSD 287 Query: 315 II--GRTINGTFFGGW---KSVDSIPKL 337 + + I+G G W KS+ IP++ Sbjct: 288 LYWDQKHIHGMIQGAWQFPKSIRMIPRM 315 >3QE3-A nrPDB Length = 355 Score = 87.4 bits (215), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 92/371 (24%), Positives = 166/371 (44%), Gaps = 56/371 (15%) Query: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESI 78 L +E + P +EV +++ + +C +D G + P+++GHEA+G V + Sbjct: 18 LRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKV 77 Query: 79 GPGVTNVKPGDKV-IPLYAP-----LCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDK 132 G V +++PGD+V I AP C+ ++ LSP C +P D L Sbjct: 78 GSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCA------TPPDDGNL---- 127 Query: 133 TSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINN 192 C+ F+ + Y K+ D+ E L+ S G A Sbjct: 128 -----CR------FYKHNANFCY---------KLPDNVTFEEGALIE-PLSVGIHAC-RR 165 Query: 193 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL----- 247 A VT G+ V G G +GL ++ KA GA++++ D+++ + KAK +GA L Sbjct: 166 AGVTLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNE 225 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 +P ++ K ++ L + ++C G +++A + T +G T + V GS+ + Sbjct: 226 SPEEIAKKVE----GLLGSKPEVTIECTGVETSIQAGIYATHSGG---TLVLVGLGSE-M 277 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 T P L+ T G ++ ++ P ++ +K N+ LVTH P +K EAF+ Sbjct: 278 TSVP--LVHAATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFET 335 Query: 368 MNQGKSVRTIL 378 +G ++ ++ Sbjct: 336 SKKGLGLKVMI 346 >1E3J-A nrPDB Length = 352 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 88/352 (25%), Positives = 151/352 (42%), Gaps = 41/352 (11%) Query: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESI 78 L +E+ + PK EV +Q+ +C +D + + P+++GHEA+G V + Sbjct: 16 LRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIGHEASGTVVKV 75 Query: 79 GPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138 G V ++K GD+V CR+C+FC NLC ++ +P D L Sbjct: 76 GKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDDGNLAR-------- 127 Query: 139 KGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPG 198 ++ + F K+ D+ +LE LL S G A A V G Sbjct: 128 ------YYVHAADFCH----------KLPDNVSLEEGALLE-PLSVGVHAC-RRAGVQLG 169 Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 +T V G G +GL +V+ KA GA ++ + + AK GA D D K + Sbjct: 170 TTVLVIGAGPIGLVSVLAAKAYGAF-VVCTARSPRRLEVAKNCGA-DVTLVVDPAKEEES 227 Query: 259 VIIELTKGGV----DFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL 314 IIE + + + +DC+G + + ++ T G T + V GS+ +T+ P Sbjct: 228 SIIERIRSAIGDLPNVTIDCSGNEKCITIGINITRTGG---TLMLVGMGSQMVTV-PLVN 283 Query: 315 IIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 R I+ ++ + P + + + N+ LVTH+ ++ +AF+ Sbjct: 284 ACAREID--IKSVFRYCNDYPIALEMVASGRCNVKQLVTHSFKLEQTVDAFE 333 >6FG0-A nrPDB Length = 352 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 89/374 (23%), Positives = 156/374 (41%), Gaps = 46/374 (12%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVID---SKFEGLAFPVIV 67 KA E G + ++ P E+ +++ A LCH+D TV+D +++ G P+ + Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAG-GLPLTL 60 Query: 68 GHEAAGIVESIGPGVTNVKPGDKVIPLYAPL-CRKCKFCLSPLTNLCGKISNLKSPASDQ 126 GHE G V +G GVT GD V +Y P C C C N C + ++L Sbjct: 61 GHEGVGTVAELGEGVTGFGVGDAVA-VYGPWGCGACHACARGRENYCTRAADLG------ 113 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVV-SDINLAKIDDDANLERVCLLGCGFSTG 185 T G + + ++Y +V S +L I D + L G + Sbjct: 114 ---------ITPPG-----YGSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPY 159 Query: 186 YGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245 + + + PGST V G+GG+G + +A A+R+I +D++ ++ A+ +GA Sbjct: 160 HAISRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADA 219 Query: 246 CLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGS 304 + + I ELT G G D G T+ A G + +G+ AG+ Sbjct: 220 AVKSG---AGAADAIRELTGGQGATAVFDFVGAQSTIDTAQQVVAVD-GHISVVGIHAGA 275 Query: 305 K---GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 G + P G ++ + W + + ++V + + ++ T T D+ Sbjct: 276 HAKVGFWMIP----FGASVVTPY---WGTRSELMEVVALARAGRLDIH---TETFTLDEG 325 Query: 362 SEAFDLMNQGKSVR 375 A+ + +G S+R Sbjct: 326 PAAYRRLREG-SIR 338 >5VM2-A nrPDB Length = 347 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 83/348 (23%), Positives = 143/348 (41%), Gaps = 47/348 (13%) Query: 28 EVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFP-------VIVGHEAAGIVESIGP 80 E+ PK EV I++ +C +D +S G P + +GHE AG V ++G Sbjct: 20 EIPVPKEDEVLIKVEYVGICGSDVHGFES---GPFIPPKDPNQEIGLGHECAGTVVAVGS 76 Query: 81 GVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKG 140 V KPGD+V C C++CL N+C + + + Sbjct: 77 RVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMAT------------------- 117 Query: 141 KPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGST 200 +P Y + Y + K+ D+ + L+ + G AA+ A V PG Sbjct: 118 QPNYR----GALTHYLCHPESFTYKLPDNMDTMEGTLVEPA-AVGMHAAML-ADVKPGKK 171 Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN--PRDLHKPIQE 258 + G G +GL + CK GA+ I +D+ ++ A+ LGAT +N D Q+ Sbjct: 172 IIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQ 231 Query: 259 VIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGR 318 ++ G D + AG + T+K A G G +G G+ + L I R Sbjct: 232 FTEDM---GADIVFETAGSAVTVKQAPYLVMRG-GKIMIVGTVPGASAINF----LKINR 283 Query: 319 TINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 + T ++ + P + + +F++ ++VTH + + +AF+ Sbjct: 284 EV--TIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >2EER-A nrPDB Length = 347 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 98/383 (25%), Positives = 154/383 (40%), Gaps = 64/383 (16%) Query: 17 EAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE--------GLAFPVIVG 68 E GKPL +E++ + PK +V I+I A +CH+D + +F G+ PV +G Sbjct: 8 EIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVKLPVTLG 67 Query: 69 HEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 HE AG +E +G V GD V C +C +LC SP Sbjct: 68 HEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC------DSP------ 115 Query: 129 MEDKTSRFTCKGKPVYHFFGTS---TFSQYTVVSDIN-LAKIDDDANLERVCLLGCGFST 184 + G + +++Y +V L K+ + +E L G +T Sbjct: 116 ----------------RWLGINYDGAYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSGVTT 159 Query: 185 GYGAAINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 A+ A + P T V G GG+G A+ KA + IIG+D+ E AK GA Sbjct: 160 --YRAVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGA 217 Query: 244 TDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 +N P+ E I +T+G G D +D +T+ + A G +G+ Sbjct: 218 DYVINASS-QDPVSE-IRRITQGKGADAVIDLNNSEKTL-SIYPYVLAKQGKYVMVGLFG 274 Query: 303 GS----KGLTIFPEELIIGRTI-NGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP 357 L E IG + N + F G S+ K + +VT T+ Sbjct: 275 ADLKYHAPLITLNEVQFIGSLVGNQSDFLGIMSLAEAGK-----------VKPMVTKTMK 323 Query: 358 FDKISEAFDLMNQGKSV-RTILI 379 ++ +EA D + K+V R +L+ Sbjct: 324 LEEANEAIDNLENFKAVGRQVLV 346 >2H6E-A nrPDB Length = 344 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 94/375 (25%), Positives = 164/375 (43%), Gaps = 49/375 (13%) Query: 7 VIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATV---IDSKFEGLAF 63 ++K KAA+ + +PL IE+V + P+ EV I+I +C TD V +++K +G Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAK-QGFRL 59 Query: 64 PVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPA 123 P+I+GHE AG + +G + VK GD V+ C++C N+C Sbjct: 60 PIILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNIC---------- 108 Query: 124 SDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVV-SDINLAKIDDDANLERVCLLGCGF 182 Q++ +T+ FS+Y +V S L K++ + +E L G Sbjct: 109 -KNQIIPGQTT--------------NGGFSEYMLVKSSRWLVKLNSLSPVEAAPLADAG- 152 Query: 183 STGYGA---AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAS-RIIGIDINSEKFVKA 238 +T GA A+ V G+GG+ + + KA + I+GI + + A Sbjct: 153 TTSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFA 212 Query: 239 KALGATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTF 297 LGA +D + +I +LT G G A+D G ET L A G+ Sbjct: 213 LELGADYVSEMKD----AESLINKLTDGLGASIAIDLVGTEETT-YNLGKLLAQEGAIIL 267 Query: 298 IGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP 357 +G+ L F + + + + G+ +G ++ + +L K K + + +P Sbjct: 268 VGMEGKRVSLEAF-DTAVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYII------KVP 320 Query: 358 FDKISEAFDLMNQGK 372 D I++AF +++G+ Sbjct: 321 LDDINKAFTNLDEGR 335 >4EEZ-A nrPDB Length = 348 Score = 77.4 bits (189), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 71/252 (28%), Positives = 117/252 (46%), Gaps = 31/252 (12%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNV 85 E E+ K +E + + +CHTD V F G ++GHE GIV+ IG V+++ Sbjct: 18 EKELRAIKPNEALLDMEYCGVCHTDLHVAAGDF-GNKAGTVLGHEGIGIVKEIGADVSSL 76 Query: 86 KPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVY 144 + GD+V + + C C++C+S C ++ N + ++ G Sbjct: 77 QVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKN---------------AGYSVDG---- 117 Query: 145 HFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF 204 + VV+D + K+ D + + C T Y AI + V PG +F Sbjct: 118 -----GMAEEAIVVADYAV-KVPDGLDPIEASSITCAGVTTY-KAIKVSGVKPGDWQVIF 170 Query: 205 GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELT 264 G GG+G A+ K +++I +DIN +K AK +GA +N D++ P+ E I ++T Sbjct: 171 GAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVN-PVDE-IKKIT 228 Query: 265 KG-GVDFALDCA 275 G GV A+ CA Sbjct: 229 GGLGVQSAIVCA 240 >3FPC-A nrPDB Length = 352 Score = 75.5 bits (184), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 96/353 (27%), Positives = 148/353 (41%), Gaps = 41/353 (11%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNV 85 E E P + ++ +A + C +D + G +I+GHEA G V +G V + Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 86 KPGDKVI-PLYAPLCRKCKFCLSPLTNLCGKISNLK-SPASDQQLMEDKTSRFTCKGKPV 143 KPGD+V+ P P R + + G ++ K S D E Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGE------------- 122 Query: 144 YHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY-GAAINNAKVTPGSTCA 202 FF + +D+NLA + + LE ++ +TG+ GA + N K+ G T Sbjct: 123 --FFHVND-------ADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELANIKL--GDTVC 171 Query: 203 VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIE 262 V G+G VGL +V G GA RI + A GATD +N ++ I E I++ Sbjct: 172 VIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN--GDIVEQILK 229 Query: 263 LTKG-GVDFALDCAGGSETMKAALDCTTAG--WGSCTFIGVAAGSKGLTIFPEELIIG-- 317 T G GVD + G T A+ G G+ ++G + I E +G Sbjct: 230 ATDGKGVDKVVIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEG---DNIDIPRSEWGVGMG 286 Query: 318 -RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLM 368 + I+G G + + +L+ K+ + LVTH FD I +AF LM Sbjct: 287 HKHIHGGLCPGGRL--RMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >3UOG-A nrPDB Length = 363 Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 87/367 (23%), Positives = 150/367 (40%), Gaps = 52/367 (14%) Query: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGHEAAGIVESIGP 80 L + E V H++ ++ +A SL + D V+++ LAFP + + +G+VE++G Sbjct: 41 LKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSGVVEAVGK 100 Query: 81 GVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKG 140 VT +PGD+VI +AP G + L+ P + + Sbjct: 101 SVTRFRPGDRVISTFAP----------------GWLDGLR-PGTGR-------------- 129 Query: 141 KPVYHFFGTS---TFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTP 197 P Y G + S+Y V+ + + L C T + A + + Sbjct: 130 TPAYETLGGAHPGVLSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRA 189 Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 G V G GGV L + KA GA I+ + EK +A ALGA +N L + Sbjct: 190 GDRVVVQGTGGVALFGLQIAKATGAEVIV-TSSSREKLDRAFALGADHGIN--RLEEDWV 246 Query: 258 EVIIELT-KGGVDFALDCAGGS---ETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEE 313 E + LT G D L+ AGG+ +++KA A G + IGV G + Sbjct: 247 ERVYALTGDRGADHILEIAGGAGLGQSLKA-----VAPDGRISVIGVLEGFEVSGPVGPL 301 Query: 314 LIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKS 373 L+ + G G ++++ + V + L ++ F ++ EA +++G Sbjct: 302 LLKSPVVQGISVGHRRALEDLVGAV-----DRLGLKPVIDMRYKFTEVPEALAHLDRGPF 356 Query: 374 VRTILIF 380 + ++ F Sbjct: 357 GKVVIEF 363 >4GKV-A nrPDB Length = 336 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 81/295 (27%), Positives = 131/295 (44%), Gaps = 33/295 (11%) Query: 33 KAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV- 91 K E +++ +CHTD V + F G VI+GHE G+V +GPGVT++KPGD+ Sbjct: 23 KHGEALLKMECCGVCHTDLHVKNGDF-GDKTGVILGHEGIGVVAEVGPGVTSLKPGDRAS 81 Query: 92 IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST 151 + + C C++C S LC + N + ++ G Sbjct: 82 VAWFYEGCGHCEYCNSGNETLCRSVKN---------------AGYSVDG---------GM 117 Query: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGL 211 + VV+D + K+ D + + C T Y A+ +K+ PG A++GLGG+G Sbjct: 118 AEECIVVADYAV-KVPDGLDSAAASSITCAGVTTY-KAVKLSKIRPGQWIAIYGLGGLGN 175 Query: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFA 271 A+ K +++I ID+N E+ A +GA +N H I++ GG A Sbjct: 176 LALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINS---HTEDAAKIVQEKTGGAHAA 232 Query: 272 LDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFG 326 + A +A+D AG G +G+ S L I P ++ G + G+ G Sbjct: 233 VVTAVAKAAFNSAVDAVRAG-GRVVAVGLPPESMSLDI-PRLVLDGIEVVGSLVG 285 >5ENV-A nrPDB Length = 347 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 82/319 (25%), Positives = 139/319 (43%), Gaps = 32/319 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 K I +E+ L +++ V PKA+E+ I + + +CHTD + + P++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E AG+V +G V K GD I C C++C G SN P +D Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYC------ELGNESN--CPHAD--- 115 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 S +T G +F QY + A I +L +V + C T Y Sbjct: 116 ----LSGYTHDG----------SFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-K 160 Query: 189 AINNAKVTPGSTCAVFG-LGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 A+ +A + G A+ G GG+G AV KA G R++GID K +++G + Sbjct: 161 ALKSANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFI 219 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 + K I +++ T GG ++ + ++A+ A G+ +G+ AG+K Sbjct: 220 DFTK-EKDIVGAVLKATDGGAHGVINVSVSEAAIEASTRYVRAN-GTTVLVGMPAGAKCC 277 Query: 308 TIFPEELIIGRTINGTFFG 326 + +++ +I G++ G Sbjct: 278 SDVFNQVVKSISIVGSYVG 296 >1R37-A nrPDB Length = 347 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 94/378 (24%), Positives = 145/378 (38%), Gaps = 54/378 (14%) Query: 17 EAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE--------GLAFPVIVG 68 E GKPL ++E+ V PK +V I++ A +CH+D + +F G+ PV +G Sbjct: 8 EIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVKLPVTLG 67 Query: 69 HEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 HE AG +E +G V GD V C +C +LC SP Sbjct: 68 HEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC------DSP------ 115 Query: 129 MEDKTSRFTCKGKPVYHFFGTS---TFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTG 185 + G + +++Y +V N L C T Sbjct: 116 ----------------RWLGINFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGITT 159 Query: 186 YGAAINNAKVTPGSTCAVFGLGGVGLS-AVMGCKAAGASRIIGIDINSEKFVKAKALGAT 244 Y A+ A + P T V G GG + AV KA + IIG+D+ E AK GA Sbjct: 160 Y-RAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGAD 218 Query: 245 DCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGS 304 +N + P+ E+ GVD +D +T+ + A G +G+ Sbjct: 219 YVINA-SMQDPLAEIRRITESKGVDAVIDLNNSEKTL-SVYPKALAKQGKYVMVGLFGAD 276 Query: 305 KGLTIFPEELIIGRTIN--GTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + LI I G+ G I +L K K ++T T+ ++ + Sbjct: 277 ---LHYHAPLITLSEIQFVGSLVGNQSDFLGIMRLAEAGKVK-----PMITKTMKLEEAN 328 Query: 363 EAFDLMNQGKSV-RTILI 379 EA D + K++ R +LI Sbjct: 329 EAIDNLENFKAIGRQVLI 346 >1UUF-A nrPDB Length = 369 Score = 71.6 bits (174), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 98/383 (25%), Positives = 156/383 (40%), Gaps = 68/383 (17%) Query: 8 IKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIV 67 +K KA A+ A +PL ++ P ++V+I+I +CH+D + S++ G +P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 68 GHEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKIS-NLKSPASD 125 GHE G V ++G V PGD V + C+ C+ C L N C ++ SP D Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPD 140 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDD-DANLERVCLLGCGFST 184 + P + G +SQ VV + + +I L V L C T Sbjct: 141 E---------------PGHTLGG---YSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGIT 182 Query: 185 GYGAAINNAKVTPGSTCAVFGLG-----GVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 239 Y + + + + PG V G+G G+ L+ MG + ++ + K AK Sbjct: 183 TY-SPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMG------AHVVAFTTSEAKREAAK 235 Query: 240 ALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTT--AGWGSCTF 297 ALGA + +N R+ E+ L DF L+ + D TT G+ T Sbjct: 236 ALGADEVVNSRN----ADEMAAHLK--SFDFILNTVAAPHNLD---DFTTLLKRDGTMTL 286 Query: 298 IGV-AAGSKGLTIFPEELIIG-RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTH- 354 +G A K +F LI+ R I G+ GG + LD H Sbjct: 287 VGAPATPHKSPEVF--NLIMKRRAIAGSMIGGIPETQEM-------------LDFCAEHG 331 Query: 355 ------TLPFDKISEAFDLMNQG 371 + D+I+EA++ M +G Sbjct: 332 IVADIEMIRADQINEAYERMLRG 354 >3TWO-A nrPDB Length = 348 Score = 71.6 bits (174), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 64/208 (30%), Positives = 92/208 (44%), Gaps = 21/208 (10%) Query: 17 EAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVE 76 E KP V P +V I I+ +CH+D S+++ +P+I GHE AGI++ Sbjct: 15 EHFKPHDFSRHAVGP---RDVLIDILYAGICHSDIHSAYSEWKEGIYPMIPGHEIAGIIK 71 Query: 77 SIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSR 135 +G GV K GD V + + C+ CK C C K+ D Sbjct: 72 EVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKVV----------FTYDCLDS 121 Query: 136 FTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKV 195 F +P H G +S VV + + +D +A LE+V L C T Y + + +KV Sbjct: 122 FH-DNEP--HMGG---YSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTY-SPLKFSKV 174 Query: 196 TPGSTCAVFGLGGVGLSAVMGCKAAGAS 223 T G+ V G GG+G AV A GA Sbjct: 175 TKGTKVGVAGFGGLGSMAVKYAVAMGAE 202 >5K1S-A nrPDB Length = 362 Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 95/374 (25%), Positives = 144/374 (38%), Gaps = 54/374 (14%) Query: 17 EAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVE 76 EAG L +E + + P EV +++ A +C+ D + P I+GHEAAG V Sbjct: 28 EAGN-LKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILGHEAAGEVI 86 Query: 77 SIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRF 136 +GP K GD+ L C C C S +LC K N Sbjct: 87 EVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLC-KTDN------------------ 127 Query: 137 TCKGKPVYHFFGTST---FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNA 193 FFG ++Q+ V L ++ + C T Sbjct: 128 --------RFFGEELPGGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRG 179 Query: 194 KVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL 252 KV G T + G GGVGLS+V + GA R+I + + K K GA + + R L Sbjct: 180 KVRAGETVLITGASGGVGLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVIVSRGL 238 Query: 253 HKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFI-----GVAAGSKG 306 + + T+G GVD A++ GS T L G G + G+ + G Sbjct: 239 D--FASDVRKRTQGAGVDVAVEIV-GSATFDQTLKSMAPG-GRVVVVGNLESGMVQLNPG 294 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEA-F 365 L I E I+ G + +D +L ++F VT +P + ++A F Sbjct: 295 LVIVKELEIL-----GAYATTQAELDEALRLTATGGVRQF-----VTDAVPLAEAAKAHF 344 Query: 366 DLMNQGKSVRTILI 379 L N+ + R +L+ Sbjct: 345 RLENREVAGRLVLV 358 >3M6I-A nrPDB Length = 363 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 82/355 (23%), Positives = 145/355 (40%), Gaps = 55/355 (15%) Query: 33 KAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIV------GHEAAGIVESIGPGVTNVK 86 K EV + + +T +C +D G P+IV GHE+AG V ++ P V ++K Sbjct: 39 KEGEVTVAVRSTGICGSDVHFWK---HGCIGPMIVECDHVLGHESAGEVIAVHPSVKSIK 95 Query: 87 PGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHF 146 GD+V +C C+ CL+ N C ++ L +P L R+ H Sbjct: 96 VGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLL-----RRYVNHPAVWCHK 150 Query: 147 FGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGL 206 G ++ ++ +++A A + A V G + G Sbjct: 151 IGNMSYENGAMLEPLSVAL----------------------AGLQRAGVRLGDPVLICGA 188 Query: 207 GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL------GATDCLNPRDLHKPIQEVI 260 G +GL ++ KAAGA ++ DI+ + AK + + L+ + K I E Sbjct: 189 GPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEICPEVVTHKVERLSAEESAKKIVE-- 246 Query: 261 IELTKGGVD--FALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGR 318 + GG++ AL+C G ++ AA+ G G IGV + + R Sbjct: 247 ---SFGGIEPAVALECTGVESSIAAAIWAVKFG-GKVFVIGVGKNEIQIPFMRASV---R 299 Query: 319 TINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKS 373 ++ F ++ ++ P+ + +N +L LVTH P + +AF+ + K+ Sbjct: 300 EVDLQF--QYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFETASDPKT 352 >4EJ6-A nrPDB Length = 370 Score = 68.6 bits (166), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 77/305 (25%), Positives = 134/305 (43%), Gaps = 32/305 (10%) Query: 13 AIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAA 72 A+ E+ + + V + P ++ +++ A +C TD ++ +F PV +GHE Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTP-PVTLGHEFC 84 Query: 73 GIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDK 132 GIV G V ++ PG ++ C +C C + NLC NL++ Sbjct: 85 GIVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLC---RNLRAIG--------- 132 Query: 133 TSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINN 192 H G F++Y +V +I L+ V C ++ Sbjct: 133 -----------IHRDGG--FAEYVLVPRKQAFEIP--LTLDPVHGAFCEPLACCLHGVDL 177 Query: 193 AKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR-- 250 + + GST A+ G G +GL V + AGA+ +I + K A+ +GAT ++P Sbjct: 178 SGIKAGSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAG 237 Query: 251 DLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIF 310 D+ + I + L GGVD ++CAG +ET+K + AG G+ +GV + + I Sbjct: 238 DVVEAIAGP-VGLVPGGVDVVIECAGVAETVKQSTRLAKAG-GTVVILGVLPQGEKVEIE 295 Query: 311 PEELI 315 P +++ Sbjct: 296 PFDIL 300 >5YAT-A nrPDB Length = 350 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 75/267 (28%), Positives = 113/267 (42%), Gaps = 45/267 (16%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATV------IDSKFEGLAFP 64 KA I G PL +++ V PK++E+ I + + +CHTD +D+K P Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNK-----LP 64 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPA 123 ++ GHE AG+V + G VT + GD I C C++C+ + C K Sbjct: 65 LVGGHEGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKAD------ 118 Query: 124 SDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFS 183 S FT G +F QY A+I +A+L V + C Sbjct: 119 ---------LSGFTHDG----------SFQQYATADATQAARIPKEADLAEVAPILCAGI 159 Query: 184 TGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 T Y A+ A + G A+ G GG S + A R++GID ++K K+LGA Sbjct: 160 TVY-KALKTADLRIGQWVAISGAGGGLGSLAVQYAKALGLRVLGIDGGADKGEFVKSLGA 218 Query: 244 ---TDCLNPRDLHKPIQEVIIELTKGG 267 D +D+ +Q +LT GG Sbjct: 219 EVFVDFTKTKDVVAEVQ----KLTNGG 241 >4ILK-A nrPDB Length = 359 Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 88/378 (23%), Positives = 155/378 (41%), Gaps = 53/378 (14%) Query: 13 AIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAA 72 +I E L I E E+ P A EVR+++ +C +D+ + +P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 73 GIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDK 132 G+++++G GV + + G++V C C C N+C ++ L A Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHAD-------- 134 Query: 133 TSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFS-----TGYG 187 FS+Y VV N KI +A ++ ++ F+ TG+G Sbjct: 135 -----------------GGFSEYAVVPAKNAWKI-PEAVADQYAVMIEPFTIAANVTGHG 176 Query: 188 AAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAA-GASRIIGIDINSEKFVKAKALGATDC 246 N T V+G G +GL+ V K +I D E+ KAK GA Sbjct: 177 QPTEN------DTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWA 230 Query: 247 LNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 +N + P+ E E KG +D A +K A+ + +G ++ Sbjct: 231 IN--NSQTPLGESFAE--KGIKPTLIIDAACHPSILKEAVTLASPA-ARIVLMGFSSEPS 285 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKF-NLDALVTHTLPFDKISEA 364 + ++ I G+ + + F + + P +V D+ +K + L+THT F +++A Sbjct: 286 EVI---QQGITGKEL--SIFSSRLNANKFP-VVIDWLSKGLIKPEKLITHTFDFQHVADA 339 Query: 365 FDL--MNQGKSVRTILIF 380 L ++Q + +L F Sbjct: 340 ISLFELDQKHCCKVLLTF 357 >5KIA-A nrPDB Length = 351 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 82/373 (21%), Positives = 149/373 (39%), Gaps = 41/373 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVI---DSKFEGLAFPVIV 67 KA E G L + V+ ++V I+I T++C TD + D + + P+ V Sbjct: 10 KALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHV 69 Query: 68 GHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQ 127 GHE G + +G V GD+V C C+ C + +LC N +++ Sbjct: 70 GHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLC---RNTVGVGVNRE 126 Query: 128 LMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLG-CGFSTGY 186 F++Y + N KI + + + + G +T Sbjct: 127 ----------------------GAFAEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHT 164 Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 + N G + G G +G+ AV K GA ++ DIN + A+ +GAT Sbjct: 165 ALSFN----LVGEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRA 220 Query: 247 LNPRDLHKPIQEVIIEL-TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 +N + +++V+ +L G D L+ +G + L+ G G +G+ Sbjct: 221 VNVS--RESLRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHG-GKVALLGIPPAQT 277 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF 365 + + + + G I G + G + ++ K+V ++ +L ++TH D + F Sbjct: 278 AID-WNQVIFKGLEIKGIY--GREMFETWYKMVAMLQS-GLDLSPIITHRFAVDDYEKGF 333 Query: 366 DLMNQGKSVRTIL 378 M G+S + IL Sbjct: 334 AAMLSGESGKVIL 346 >5VKT-A nrPDB Length = 362 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 48/167 (28%), Positives = 72/167 (43%), Gaps = 23/167 (13%) Query: 36 EVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPL 94 +V I+++ +CHTD VI +++ +PV+ GHE G+V +G GVT K GD V + Sbjct: 36 DVTIKVLFCGICHTDLHVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAGDTVGVGY 95 Query: 95 YAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST--- 151 + CR C+ C + N C + L S D +H G +T Sbjct: 96 FVDSCRTCESCSTGHENYCPDLV-LTSNGVD------------------HHHHGATTKGG 136 Query: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPG 198 FS VVS + ++ + L+ L C T Y A PG Sbjct: 137 FSDVLVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPG 183 >2OUI-A nrPDB Length = 360 Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 90/343 (26%), Positives = 140/343 (40%), Gaps = 43/343 (12%) Query: 39 IQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVI-PLYAP 97 ++ +A + C +D + + G +I+GHEA G + +G V +K GDKVI P P Sbjct: 29 VRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRLKVGDKVIVPAITP 88 Query: 98 LCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTV 157 + + S P ++ G + F FS+ Sbjct: 89 -------------DWGEEESQRGYPMHSGGML----------GGWKFSNFKDGVFSEVFH 125 Query: 158 V--SDINLAKIDDDANLERVCLLGCGFSTGY-GAAINNAKVTPGSTCAVFGLGGVGLSAV 214 V +D NLA + D E +L +TG+ GA + N K+ G T V G+G VGL +V Sbjct: 126 VNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKL--GDTVCVIGIGPVGLMSV 183 Query: 215 MGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDFALD 273 G GA RI + A GATD +N ++ I E I++ T G GVD + Sbjct: 184 AGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN--GDIVEQILKATDGKGVDKVVI 241 Query: 274 CAGGSETMKAALDCTTAG--WGSCTFIGVAAGSKGLTIFPEELIIG---RTINGTFFGGW 328 G T A+ G G+ ++G + I E +G + I+G G Sbjct: 242 AGGDVHTFAQAVKMIKPGSDIGNVNYLGEG---DNIPIPRSEWGVGMGHKHIHGGLTPGG 298 Query: 329 KSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQ 370 + + KL + K + L+TH +K+ +A LM Sbjct: 299 RV--RMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKN 339 >1WLY-A nrPDB Length = 333 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 97/385 (25%), Positives = 145/385 (37%), Gaps = 74/385 (19%) Query: 12 AAIAWEAGKP--LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAF---PVI 66 AA+ + G P EEV+V P +VR++ A + D L P++ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPPIV 63 Query: 67 VGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 VG EAA +VE +GPGVT+ G++V C CL PL Sbjct: 64 VGFEAAAVVEEVGPGVTDFTVGERV----------CT-CLPPL----------------- 95 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC---GFS 183 +SQ + L K+ D +L+ V L G G + Sbjct: 96 -----------------------GAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMT 132 Query: 184 TGYGAAINNAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 Y KV PG + GG+G V + GA+ +IG EK A+ LG Sbjct: 133 AQY-LLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGAT-VIGTVSTEEKAETARKLG 190 Query: 243 ATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 +N + EV+ E+T G GVD D G +T++ +LDC G C G A Sbjct: 191 CHHTINYST--QDFAEVVREITGGKGVDVVYDSI-GKDTLQKSLDCLRP-RGMCAAYGHA 246 Query: 302 AGSKGLTIFPEE------LIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHT 355 +G E+ L I R + +D K + D K L + V T Sbjct: 247 SGVADPIRVVEDLGVRGSLFITRPALWHYMSNRSEIDEGSKCLFD-AVKAGVLHSSVAKT 305 Query: 356 LPFDKISEAFDLMNQGKSVRTILIF 380 P + + A M +++ +I++ Sbjct: 306 FPLREAAAAHKYMGGRQTIGSIVLL 330 >3WLE-A nrPDB Length = 341 Score = 61.6 bits (148), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 89/329 (27%), Positives = 145/329 (44%), Gaps = 54/329 (16%) Query: 25 EEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL--AFPVIVGHEAAGIVESIGPGV 82 ++ V PKA ++ +++ A LCH+D VI +EGL ++GHE AG V ++G V Sbjct: 27 NDLPVHKPKAGQLLLKVDAVGLCHSDLHVI---YEGLDCGDNYVMGHEIAGTVAAVGDDV 83 Query: 83 TNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKP 142 N K GD+V + C CK+C + N+C K+ D Sbjct: 84 INYKVGDRVACVGPNGCGGCKYCRGAIDNVC------KNAFGD----------------- 120 Query: 143 VYHFFGTST---FSQYTVVSD-INLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPG 198 +FG + QY +V+ NL++I D+ + + T Y AI A+V+P Sbjct: 121 ---WFGLGYDGGYQQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPY-HAIKMAQVSPT 176 Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 S + G GG+G +A+ KA GA ++ +D E +AK LGA + E Sbjct: 177 SNILLIGAGGLGGNAIQVAKAFGA-KVTVLDKKKEARDQAKKLGA----------DAVYE 225 Query: 259 VIIE-LTKGGVDFALDCAGGSETMKAALD-CTTAGWGSCTFIGVAAGSKGLTIFPEELII 316 + E ++ G D +++A D C + V G+ L+ +L + Sbjct: 226 TLPESISPGSFSACFDFV----SVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGDLAL 281 Query: 317 GR-TINGTFFGGWKSVDSIPKLVTDYKNK 344 I G+F+G +D + KLV++ K K Sbjct: 282 REIRILGSFWGTTNDLDDVLKLVSEGKVK 310 >4JLW-A nrPDB Length = 399 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 71/257 (27%), Positives = 117/257 (45%), Gaps = 42/257 (16%) Query: 35 HEVRIQIIATSLCHTDATVIDSKF---EGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV 91 H V +++++T++C +D ++ + EGL ++GHE G V IG GV +K GD V Sbjct: 35 HGVILRVVSTNICGSDQHMVRGRTTAPEGL----VLGHEITGEVVEIGRGVETMKIGDLV 90 Query: 92 IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST 151 + C C+ C T +C ++ ++ + Y + Sbjct: 91 SVPFNVACGHCRTCKEQHTGVCLTVNPARAGGA-------------------YGYVDMGG 131 Query: 152 F----SQYTVV--SDINLAKI-DDDANLERVCLLGCG---FSTGYGAAINNAKVTPGSTC 201 + ++Y +V +D NL K+ + +A +E++ L C TGY A+ A V PGST Sbjct: 132 WVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGAVT-AGVGPGSTV 190 Query: 202 AVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG--ATDCLNPRDLHKPIQEV 259 + G G VGL+A + GA+ +I D+N + AK G D LH+ I + Sbjct: 191 YIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLSKDTPLHEQIAAL 250 Query: 260 IIELTKGGVDFALDCAG 276 + E VD A+D G Sbjct: 251 LGEPE---VDCAVDAVG 264 >1KOL-A nrPDB Length = 398 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 114/251 (45%), Gaps = 30/251 (11%) Query: 35 HEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPL 94 H V +++++T++C +D ++ + +++GHE G V G V N++ GD V Sbjct: 34 HGVILKVVSTNICGSDQHMVRGRTTA-QVGLVLGHEITGEVIEKGRDVENLQIGDLVSVP 92 Query: 95 YAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQ 154 + C +C+ C T +C ++ ++ G Y G T Q Sbjct: 93 FNVACGRCRSCKEMHTGVCLTVNPARA-----------------GGAYGYVDMGDWTGGQ 135 Query: 155 --YTVV--SDINLAKI-DDDANLERVCLLGCG---FSTGYGAAINNAKVTPGSTCAVFGL 206 Y +V +D NL K+ D D +E++ L C TGY A+ A V PGST V G Sbjct: 136 AEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAVT-AGVGPGSTVYVAGA 194 Query: 207 GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELT-K 265 G VGL+A + GA+ +I D+N + AKA G + L P+ E I L + Sbjct: 195 GPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFE--IADLSLDTPLHEQIAALLGE 252 Query: 266 GGVDFALDCAG 276 VD A+D G Sbjct: 253 PEVDCAVDAVG 263 >6C49-A nrPDB Length = 350 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 89/379 (23%), Positives = 158/379 (41%), Gaps = 59/379 (15%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHE 70 +A A +AG+ L + + + H+V +++ LCH+D +V+++++ +PV+ GHE Sbjct: 15 QAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHE 74 Query: 71 AAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLM 129 G + ++G ++ G +V I A C+ C C+ QQ++ Sbjct: 75 IIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECI-----------------GGQQVL 117 Query: 130 EDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLA-KIDDDANLERVCLLGCGFSTGYGA 188 C G+ + G + V + A + +D + E L CG T + Sbjct: 118 --------CTGENIATIVGHAGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDP 169 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + + K+ V G+GG+G A+ KA G I N +K + KA+GA +N Sbjct: 170 LLKH-KIQATHHVGVIGIGGLGHIAIKLLKAWGC-EITAFSSNPDKTEELKAMGADHVVN 227 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 RD ++ KG D L + +A + T A GS F+ GLT Sbjct: 228 SRDTEA------VKAQKGKFDLLLSTVNVTLNWRAFIS-TLAPNGSLHFL-------GLT 273 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIP--------KLVTDYKNKKFNLDALVTHTLPFDK 360 + P + +G I+G KSV P +L+ KK A P + Sbjct: 274 LEPVPVSVGSLIDGA-----KSVTGSPTGSPAALRQLLKFAARKKI---APQIELFPMSQ 325 Query: 361 ISEAFDLMNQGKSVRTILI 379 ++EA + ++ G++ I++ Sbjct: 326 LNEAIERLHSGQARYRIVL 344 >3IP1-A nrPDB Length = 404 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 70/276 (25%), Positives = 113/276 (40%), Gaps = 51/276 (18%) Query: 24 IEEV-EVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL-------AFPVIVGHEAAGIV 75 +EEV E K E+ I++ A +C +D + + EG FPV +GHE +G+V Sbjct: 44 VEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFSGVV 103 Query: 76 ESIGPGVTNVKPGDKVIPLYAPLCRK-------CKFCLSPLTNLCGKISNLKSPASDQQL 128 GP N + +K + P+C + C+ C N C ++ L Sbjct: 104 VEAGPEAINRRT-NKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELG-------- 154 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVS---DINLAKIDDDANLERVCLLGCGF--- 182 F G F++Y V +L +++ +R+ L G Sbjct: 155 -------FNVDG----------AFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPT 197 Query: 183 STGYGAAI-NNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 S Y A I + PG + G G +GL+AV K AGAS++I + + + AK L Sbjct: 198 SVAYNAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKEL 257 Query: 242 GATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAG 276 GA ++P + E +++ T G G L+ G Sbjct: 258 GADHVIDP--TKENFVEAVLDYTNGLGAKLFLEATG 291 >5H82-A nrPDB Length = 389 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 50/190 (26%), Positives = 77/190 (40%), Gaps = 6/190 (3%) Query: 35 HEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IP 93 H+V+ +++ LC D + + +P + GHE GIV IG V K GDKV + Sbjct: 54 HDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVGVG 113 Query: 94 LYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFS 153 + C KC+ C L C K+ A E+ T G +G +S Sbjct: 114 NFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSD---ENNTVYGDVSGDGEDRIYG--GYS 168 Query: 154 QYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSA 213 V ++ + + ++ L + CG Y + PG + V G G +G A Sbjct: 169 NIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKLA 228 Query: 214 VMGCKAAGAS 223 V KA GA+ Sbjct: 229 VKFAKAFGAN 238 >5H83-A nrPDB Length = 360 Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 47/85 (55%), Gaps = 1/85 (1%) Query: 35 HEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IP 93 ++V+ +++ C+ D + +KF +P ++GHE G+V IG V K GDKV + Sbjct: 40 NDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVGVG 99 Query: 94 LYAPLCRKCKFCLSPLTNLCGKISN 118 + C KC+ C++ + N C K+ + Sbjct: 100 GFVGACEKCEMCVNGVENNCSKVES 124 >5FI5-A nrPDB Length = 357 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Query: 35 HEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IP 93 H+V+++++ C D + +KF ++P ++GHE G V +G V K GDKV + Sbjct: 43 HDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVGVA 102 Query: 94 LYAPLCRKCKFCLSPLTNLCGKISNLKS 121 C KC+ C + + N C + ++ S Sbjct: 103 SIIETCGKCEMCTNEVENYCPEAGSIDS 130 >6DKH-A nrPDB Length = 346 Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 75/348 (21%), Positives = 131/348 (37%), Gaps = 42/348 (12%) Query: 39 IQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLY 95 +QI +C +D G + P+++GHE G V I + + G V Sbjct: 35 VQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINP 92 Query: 96 APLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQY 155 + C CK+C+ N C + RF G +Y F++Y Sbjct: 93 SKPCGHCKYCIEHNENQCTDM------------------RFF--GSAMYFPHVDGGFTRY 132 Query: 156 TVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVM 215 +V A+ E+V + AA + A G + G+G +G V Sbjct: 133 KMVETSQCVPYPAKAD-EKVMAFAEPLAVAIHAA-HQAGELQGKRVFISGVGPIGCLIVS 190 Query: 216 GCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR--DLHKPIQEVIIELTKGGVDFALD 273 K GA+ I+ D++ K +GA +NP+ D+ E KG D + + Sbjct: 191 AVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAE------KGYFDVSFE 244 Query: 274 CAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDS 333 +G ++ L+ T A G +G+ + FP +IG+ I + G ++ Sbjct: 245 VSGHPSSVNTCLEVTRA-RGVMVQVGMGG---AMAEFPMMTLIGKEI--SLRGSFRFTSE 298 Query: 334 IPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM-NQGKSVRTILIF 380 V+ N N L++ PF + EA ++ ++ + L+F Sbjct: 299 FNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF 346 >1YQX-A nrPDB Length = 366 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 36 EVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPL 94 +VR +++ +CH+D I + + +P++ GHE G V +G V V GDKV + Sbjct: 43 DVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVGVGC 102 Query: 95 YAPLCRKCKFCLSPLTNLCGKI 116 C C+ C + L N C K+ Sbjct: 103 LVGACHSCESCANDLENYCPKM 124 >2VCY-A nrPDB Length = 344 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 74/335 (22%), Positives = 124/335 (37%), Gaps = 74/335 (22%) Query: 9 KCKAAIAWEAGKPLCIEEV---EVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL-AFP 64 + +A + G P + E+ E+A + +VR++++A + +D +I + L P Sbjct: 13 RVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELP 72 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 + G+E V ++G VT +KPGD VIP A Sbjct: 73 AVGGNEGVAQVVAVGSNVTGLKPGDWVIPANA---------------------------- 104 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFST 184 G T+ V S+ L ++ D L+ LG T Sbjct: 105 -----------------------GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCT 141 Query: 185 GYGAAINNAKVTPG-STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVK----AK 239 Y ++ ++ PG S GVG AV+ AA R I + + K K Sbjct: 142 AYRMLMDFEQLQPGDSVIQNASNSGVG-QAVIQIAAALGLRTINVVRDRPDIQKLSDRLK 200 Query: 240 ALGATDCLNPRDLHKP-IQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFI 298 +LGA + +L +P ++ ++ + AL+C GG + + L G T+ Sbjct: 201 SLGAEHVITEEELRRPEMKNFFKDMPQP--RLALNCVGGKSSTE-LLRQLARGGTMVTYG 257 Query: 299 GVA----AGSKGLTIFPEELIIGRTINGTFFGGWK 329 G+A S L IF + + G + WK Sbjct: 258 GMAKQPVVASVSLLIFKD-----LKLRGFWLSQWK 287 >3JYN-A nrPDB Length = 325 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 6/138 (4%) Query: 131 DKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVC-LLGCGFSTGYGAA 189 D+ +RF + Y +S+ V+ + NL K+ D + E+ L+ G + Y Sbjct: 74 DEVTRFKVGDRVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQY-LL 132 Query: 190 INNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 +V PG GGVG A KA GA ++IG + EK AKALGA + ++ Sbjct: 133 RQTYQVKPGEIILFHAAAGGVGSLACQWAKALGA-KLIGTVSSPEKAAHAKALGAWETID 191 Query: 249 PRDLHKPIQEVIIELTKG 266 H+ + + ++ELT G Sbjct: 192 YS--HEDVAKRVLELTDG 207 >5Z0C-A nrPDB Length = 374 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Query: 36 EVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPL 94 +V +++ +CH+D I +++ +P + GHE G V +G V K GDKV + Sbjct: 40 DVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGC 99 Query: 95 YAPLCRKCKFCLSPLTNLC 113 C C C + L N C Sbjct: 100 IVGSCHSCPNCNNHLENYC 118 >4OAQ-A nrPDB Length = 367 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 5/102 (4%) Query: 16 WEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFP-VIVGHEAAGI 74 W K E ++ P H+V ++ LC++D + + ++ L ++VGHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGE 76 Query: 75 VESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGK 115 V ++G VT K GD+V I + CR C+ C S C + Sbjct: 77 VIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQ 118 >1QOR-A nrPDB Length = 327 Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Query: 19 GKPLCIEEVEVAP--PKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVE 76 G P ++ VE P P +E++++ A + D + + + P +G EAAGIV Sbjct: 11 GGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGIVS 70 Query: 77 SIGPGVTNVKPGDKVI 92 +G GV ++K GD+V+ Sbjct: 71 KVGSGVKHIKAGDRVV 86 Score = 31.6 bits (70), Expect = 0.61, Method: Compositional matrix adjust. Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 3/81 (3%) Query: 207 GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG 266 GGVGL A KA GA ++IG ++K A GA +N R+ + + E + E+T G Sbjct: 151 GGVGLIACQWAKALGA-KLIGTVGTAQKAQSALKAGAWQVINYRE--EDLVERLKEITGG 207 Query: 267 GVDFALDCAGGSETMKAALDC 287 + + G +T + +LDC Sbjct: 208 KKVRVVYDSVGRDTWERSLDC 228 >3SLK-A nrPDB Length = 795 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 19 GKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESI 78 G L E AP EVRI + A + DA + + G+A +G E AG+V Sbjct: 223 GLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMYPGVAS---LGSEGAGVVVET 279 Query: 79 GPGVTNVKPGDKVI 92 GPGVT + PGD+V+ Sbjct: 280 GPGVTGLAPGDRVM 293 >2DPH-A nrPDB Length = 398 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 76/292 (26%), Positives = 123/292 (42%), Gaps = 42/292 (14%) Query: 35 HEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPL 94 H V +++++T++C +D + +F + ++GHE G V G V + GD V Sbjct: 33 HAVILKVVSTNICGSDQHIYRGRFI-VPKGHVLGHEITGEVVEKGSDVELMDIGDLVSVP 91 Query: 95 YAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQ 154 + C +C+ C +++C +NL +P +D F KG + ++ Sbjct: 92 FNVACGRCRNCKEARSDVCE--NNLVNPDADLGAFG-----FDLKG-------WSGGQAE 137 Query: 155 YTVV--SDINLAKI-DDDANLERV---CLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGG 208 Y +V +D L K D + +E++ L+ TG+ ++ A V PGS + G G Sbjct: 138 YVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPTGFHGCVS-AGVKPGSHVYIAGAGP 196 Query: 209 VGLSAVMGCKAAGASRIIGIDINSE--KFVKAKALGATDCLNPRDLHKPIQEVIIELTKG 266 VG A G + GA+ +I D N E K + D N L I ++ L K Sbjct: 197 VGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFETIDLRNSAPLRDQIDQI---LGKP 253 Query: 267 GVDFALDCAG----------GSETMKAAL----DCTTAGWGSCTFIGVAAGS 304 VD +D G +ET AL D AG G+ G+ GS Sbjct: 254 EVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAG-GAIGIPGIYVGS 304 >4DVJ-A nrPDB Length = 363 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 8/98 (8%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIE------EVEVAPPKAHEVRIQIIATSLCHTDATVI 54 +GT+ + A+ + P+ + E+ P H++ +++ A S+ D V Sbjct: 13 LGTENLYFQSMKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVR 72 Query: 55 DS-KFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV 91 S +G + VI G++AAGIV ++GP VT +PGD+V Sbjct: 73 RSTPPDGTDWKVI-GYDAAGIVSAVGPDVTLFRPGDEV 109 >5A3V-A nrPDB Length = 329 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 3/76 (3%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATV---IDSKFEGLAFPVIVGHEAAGIVESIGPGV 82 +V V PK++EV +++ ATSL D + + F FP I + AG V +G GV Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGV 84 Query: 83 TNVKPGDKVIPLYAPL 98 N K GDKV+ + + L Sbjct: 85 KNFKAGDKVVAVLSHL 100 >2CDC-A nrPDB Length = 366 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 8/83 (9%) Query: 36 EVRIQIIATSLCHTDATVIDSKFEGLAFP-----VIVGHEAAGIVESIGPGVTNVKPGDK 90 +++I+ I +C D +++ K P +++GHEA G+VE G + GD Sbjct: 28 KIKIRTIYNGICGADREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYHGFSQ---GDL 84 Query: 91 VIPLYAPLCRKCKFCLSPLTNLC 113 V+P+ C C+ CL + C Sbjct: 85 VMPVNRRGCGICRNCLVGRPDFC 107 >4RVS-A nrPDB Length = 329 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 14/132 (10%) Query: 17 EAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFP----VIVGHEAA 72 E G P + V+ P+ + I A ++ ID+ F +P ++G E Sbjct: 9 ETGGPGVLRHVDQPQPQPGHGELLIKAEAIG---VNFIDTYFRSGQYPRELPFVIGSEVC 65 Query: 73 GIVESIGPGV----TNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKI-SNLKSPASDQQ 127 G VE++GPGV T + GD+V+ A +FC +P +L K+ ++ S + Sbjct: 66 GTVEAVGPGVTAADTAISVGDRVVSASANGA-YAEFCTAP-ASLTAKVPDDVTSEVAASA 123 Query: 128 LMEDKTSRFTCK 139 L++ T+ + K Sbjct: 124 LLKGLTAHYLLK 135 >2OBY-A nrPDB Length = 338 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 5/128 (3%) Query: 153 SQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGVGL 211 +QY V + L I + L + + + T + V G + GL GVG Sbjct: 102 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 161 Query: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDF 270 +A+ + AGA ++ + +K A+ LGA N + + E ++ TKG GV+ Sbjct: 162 AAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYKK--EDFSEATLKFTKGAGVNL 218 Query: 271 ALDCAGGS 278 LDC GGS Sbjct: 219 ILDCIGGS 226 >2VN8-A nrPDB Length = 375 Score = 37.4 bits (85), Expect = 0.012, Method: Compositional matrix adjust. Identities = 77/340 (22%), Positives = 120/340 (35%), Gaps = 84/340 (24%) Query: 57 KFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKI 116 K +G FP+ +G + +G+V G V KPGD+V P + G + Sbjct: 88 KIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQ-------------GTL 134 Query: 117 SNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVC 176 S + ++ + K T + + +S V +N D + +RV Sbjct: 135 SEFVVVSGNE--VSHKPKSLTHTQAASLPYVALTAWSAINKVGGLN----DKNCTGKRVL 188 Query: 177 LLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFV 236 +LG GGVG A+ KA A ++ + V Sbjct: 189 ILGAS-------------------------GGVGTFAIQVMKAWDAHVTAVCSQDASELV 223 Query: 237 KAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCT 296 + LGA D ++ + ++E + L DF LD GGS T A D W T Sbjct: 224 --RKLGADDVIDYKS--GSVEEQLKSLKP--FDFILDNVGGS-TETWAPDFLKK-WSGAT 275 Query: 297 FI----------------------GVAAGSKGLTIFPEELIIGRTINGTFF-GGWKSVDS 333 ++ GV GSK L F + G FF +D Sbjct: 276 YVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWK----GVHYRWAFFMASGPCLDD 331 Query: 334 IPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKS 373 I +LV K + ++ T PF K+ EAF + +G + Sbjct: 332 IAELVDAGK-----IRPVIEQTFPFSKVPEAFLKVERGHA 366 >3B70-A nrPDB Length = 371 Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust. Identities = 66/263 (25%), Positives = 94/263 (35%), Gaps = 61/263 (23%) Query: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFST--------GYGAAINNAKVTPGSTCAV 203 FSQYTV AKI + E+ L G ST G +A P + V Sbjct: 107 FSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTAGLAMKLLGLPLPSPSADQPPTHSKPV 166 Query: 204 FGL--GGVGLSAVMGCKAAGASRIIGIDI-NSEKFVKAKALGATDCLNPRDLHKPIQEVI 260 + L GG +A + + S I I + F AK+ GA + + R + + + I Sbjct: 167 YVLVYGGSTATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVFDYRAPN--LAQTI 224 Query: 261 IELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG-----LTIFPEELI 315 TK + +ALDC E S TF A G G L FPE Sbjct: 225 RTYTKNNLRYALDCITNVE--------------STTFCFAAIGRAGGHYVSLNPFPEHAA 270 Query: 316 IGR------TINGTFFG---GWKSVDSIPKLVTDYKNKKFNLD------------ALVTH 354 + T+ T FG W + P + ++F D LV H Sbjct: 271 TRKMVTTDWTLGPTIFGEGSTWPAPYGRPG---SEEERQFGEDLWRIAGQLVEDGRLVHH 327 Query: 355 TLP-----FDKISEAFDLMNQGK 372 L FD I + +L+ +G+ Sbjct: 328 PLRVVQGGFDHIKQGMELVRKGE 350 >3FBG-A nrPDB Length = 346 Score = 37.0 bits (84), Expect = 0.015, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 6/67 (8%) Query: 27 VEVAPPKAHE--VRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTN 84 +++ PK HE V+IQ I+ + T ++D P ++G +A G+VES+G VT Sbjct: 25 LDIPEPKVHEILVKIQSISVNPVDTKQRLMDVS----KAPRVLGFDAIGVVESVGNEVTM 80 Query: 85 VKPGDKV 91 GD V Sbjct: 81 FNQGDIV 87 >1Q1N-A nrPDB Length = 360 Score = 36.2 bits (82), Expect = 0.024, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 3/98 (3%) Query: 31 PPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGP-GVTNVKPGD 89 P H++ I+I A +C +D + + P++VGHE G V +GP + +K G Sbjct: 30 PFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKVGQ 89 Query: 90 KV-IPLYAPLCRKCKFCLSPLTNLCGK-ISNLKSPASD 125 +V + C +C C + C K ++ P D Sbjct: 90 RVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYED 127 >1YB5-A nrPDB Length = 351 Score = 35.8 bits (81), Expect = 0.028, Method: Compositional matrix adjust. Identities = 55/258 (21%), Positives = 98/258 (37%), Gaps = 59/258 (22%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIE---EVEVAPPKAHEVRIQIIATSLCHTDATVIDSK 57 M T K+++ A +E G P ++ ++ V PK H+V I++ A + + + Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 58 FEGLAF-PVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKI 116 + P G + AG++E++G + K GD+V Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVF------------------------ 116 Query: 117 SNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVC 176 TS G Y + +D + K+ + + ++ Sbjct: 117 ----------------TSSTISGGYAEY-----------ALAADHTVYKLPEKLDFKQGA 149 Query: 177 LLGCGFSTGYGAAINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKF 235 +G + T Y A I++A V G + V G GGVGL+A +A G +I+G E Sbjct: 150 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGL-KILGTAGTEEGQ 208 Query: 236 VKAKALGATDCLNPRDLH 253 GA + N R+++ Sbjct: 209 KIVLQNGAHEVFNHREVN 226 >3TQH-A nrPDB Length = 321 Score = 35.0 bits (79), Expect = 0.051, Method: Compositional matrix adjust. Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 13/138 (9%) Query: 152 FSQYTVVS-DINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGV 209 +++Y S D + K++ + L+ L G + A+N A+V G + G GGV Sbjct: 108 YAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTAL--QALNQAEVKQGDVVLIHAGAGGV 165 Query: 210 GLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVD 269 G A+ K G + I + F+ KALGA C+N + E + VD Sbjct: 166 GHLAIQLAKQKGTTVITTASKRNHAFL--KALGAEQCINYHE------EDFLLAISTPVD 217 Query: 270 FALDCAGGSETMKAALDC 287 +D GG ++ ++DC Sbjct: 218 AVIDLVGGDVGIQ-SIDC 234 >3HZZ-A nrPDB Length = 467 Score = 34.7 bits (78), Expect = 0.066, Method: Compositional matrix adjust. Identities = 64/251 (25%), Positives = 93/251 (37%), Gaps = 58/251 (23%) Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 I+G + AG+V GPGV +PGD+V+ CLS L+SP Sbjct: 138 IIGSDLAGVVLRTGPGVNAWQPGDEVV----------AHCLS---------VELESPDGH 178 Query: 126 QQLMEDKTSRFTCKGKPVYHF---FGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 M D R ++ F FG ++ +V L E G Sbjct: 179 DDTMLDPEQR-------IWGFETNFG--GLAEIALVKTNQLMPKPKHLTWEEAAAPGLVN 229 Query: 183 STGYGAAI--NNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGAS--------------RI 225 ST Y + N A + G ++G GG+G A A GA+ R Sbjct: 230 STAYRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSPQKAEICRS 289 Query: 226 IG----IDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSET 280 +G ID N+E + K +P++ K + I ELT G +D + G ET Sbjct: 290 MGAEAIIDRNAEGY---KFWKDEHTQDPKEW-KRFGKRIRELTGGEDIDIVFEHP-GRET 344 Query: 281 MKAALDCTTAG 291 A++ T G Sbjct: 345 FGASVYVTRKG 355 >5ILO-A nrPDB Length = 271 Score = 34.3 bits (77), Expect = 0.083, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 12/82 (14%) Query: 205 GLGGVGLSAVMGCKAAGASRIIGIDI--NSEKFVKAKALGAT--------DCLNPRDLHK 254 G GG+GL AAGA+++ ID+ N E+FVK +A T D N + + Sbjct: 23 GAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEA 82 Query: 255 PIQEVIIELTKGGVDFALDCAG 276 +E I T G +D ++ AG Sbjct: 83 TYEE--IAKTFGNIDIVVNVAG 102 >3QWB-A nrPDB Length = 334 Score = 34.3 bits (77), Expect = 0.10, Method: Compositional matrix adjust. Identities = 59/239 (24%), Positives = 83/239 (34%), Gaps = 66/239 (27%) Query: 48 HTDATVIDSKFEGLAFP----VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCK 103 +T I+S F +P ++G EA+G V + G GVTN + GD+V Sbjct: 44 YTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGVTNFEVGDQV------------ 91 Query: 104 FCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDIN- 162 ISN STF+QY+ +S Sbjct: 92 ----------AYISN-------------------------------STFAQYSKISSQGP 110 Query: 163 LAKIDDDANLERVCLLGCGF---STGYGAAINNAKVTPGSTCAVF-GLGGVGLSAVMGCK 218 + K+ + E + L G T V G +F GGVGL K Sbjct: 111 VMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLK 170 Query: 219 AAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAG 276 GA I + EK AK GA +N + I +++ T G GVD + D G Sbjct: 171 MKGA-HTIAVASTDEKLKIAKEYGAEYLINAS--KEDILRQVLKFTNGKGVDASFDSVG 226 >4A27-A nrPDB Length = 349 Score = 32.0 bits (71), Expect = 0.44, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 32 PKAHEVRIQIIATSLCHTDATVIDSKFEGL-AFPVIVGHEAAGIVESIGPGVTNVKPGDK 90 P+ E++I++ A L D V + P++ G E +GIVE++G V + GD+ Sbjct: 28 PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 87 Query: 91 VI 92 V+ Sbjct: 88 VM 89 >4IDE-A nrPDB Length = 332 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%) Query: 33 KAHEVRIQIIATSLCHTDATVIDSKFEGL--AFPVIVGHEAAGIVESIGPGVTNVKPGDK 90 K +V I+++A SL D F+ P I G++ AG+V +G VT K GD+ Sbjct: 51 KEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVTKFKVGDE 110 Query: 91 V 91 V Sbjct: 111 V 111 >4J6F-A nrPDB Length = 382 Score = 31.6 bits (70), Expect = 0.57, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 16/84 (19%) Query: 25 EEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKF----------------EGLAFPVIVG 68 +V V P A EV I++ A + +TD V + + L FP I G Sbjct: 52 RDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTLTFPRIQG 111 Query: 69 HEAAGIVESIGPGVTNVKPGDKVI 92 + G + ++G GV + G++V+ Sbjct: 112 TDTVGHIVAVGEGVDRARIGERVM 135 >2VWH-A nrPDB Length = 357 Score = 31.6 bits (70), Expect = 0.62, Method: Compositional matrix adjust. Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 12/88 (13%) Query: 13 AIAWEAG--KPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFP-----V 65 AIA + G +P+ IE+ P++ E ++ + + TD VI G FP + Sbjct: 3 AIAVKRGEDRPVVIEKPR-PEPESGEALVRTLRVGVDGTDHEVIAGGHGG--FPEGEDHL 59 Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIP 93 ++GHEA G+V + P T ++ GD V+P Sbjct: 60 VLGHEAVGVV--VDPNDTELEEGDIVVP 85 >4IHE-A nrPDB Length = 419 Score = 31.2 bits (69), Expect = 0.72, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 3/34 (8%) Query: 244 TDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGG 277 TD L+PR+L + I V++ GG F LD AGG Sbjct: 103 TDALDPRNLVQTIDAVVL---TGGSAFGLDAAGG 133 >3QTD-A nrPDB Length = 449 Score = 31.2 bits (69), Expect = 0.82, Method: Compositional matrix adjust. Identities = 16/62 (25%), Positives = 28/62 (45%), Gaps = 3/62 (4%) Query: 297 FIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTL 356 F+G +G +++ + + + F W S+D P LV + F+ D L T+ Sbjct: 259 FLGAISGG---SLYRKSSFLEGALGQRLFPEWLSIDERPHLVGALGSASFDSDGLATYAK 315 Query: 357 PF 358 PF Sbjct: 316 PF 317 >4EYE-A nrPDB Length = 342 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGHEAAGIVESIGP 80 L +VE + V + + A +C D + +++ + P + G E AG+V S P Sbjct: 36 LVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFVPGIETAGVVRS-AP 94 Query: 81 GVTNVKPGDKVI 92 + +KPGD+V+ Sbjct: 95 EGSGIKPGDRVM 106 >1MV8-A nrPDB Length = 436 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Query: 202 AVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKF 235 ++FGLG VG + GC +A +IG+D++S K Sbjct: 4 SIFGLGYVG-AVCAGCLSARGHEVIGVDVSSTKI 36 >1JGT-A nrPDB Length = 513 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 194 KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRI----IGIDINSEKFVKAKALGATDCLNP 249 +VTPG T V GG+ S V C A + +G D ++E F +A+A+ Sbjct: 237 RVTPGDTPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNE-FREARAVVDHLRTRH 295 Query: 250 RDLHKPIQEVIIEL 263 R++ P E++ +L Sbjct: 296 REITIPTTELLAQL 309 >1ZOD-A nrPDB Length = 433 Score = 28.5 bits (62), Expect = 4.4, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 56/139 (40%), Gaps = 17/139 (12%) Query: 242 GATDCLNPRDLHKPIQEVIIEL---TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFI 298 G D L L +P+ ++ L T G+D AL + G+E+ +AA+ G + Sbjct: 73 GKLDHLFSEMLSRPVVDLATRLANITPPGLDRALLLSTGAESNEAAIRMAKLVTGKYEIV 132 Query: 299 GVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYK-NKKFNLDALVTHTLP 357 G A G+T G + T+ G K V P V + F Sbjct: 133 GFAQSWHGMT--------GAAASATYSAGRKGVG--PAAVGSFAIPAPFTYRPRFERNGA 182 Query: 358 FDKISE---AFDLMNQGKS 373 +D ++E AFDL+++ S Sbjct: 183 YDYLAELDYAFDLIDRQSS 201 >3VV5-A nrPDB Length = 260 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 6/100 (6%) Query: 247 LNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 L PR + + ++I+L +G DF + G +E A+D T + CT GV KG Sbjct: 75 LKPRWIAQSFDTLLIQLNQGRFDFVIASHGITEERARAVDFTNPHY--CTG-GVIVSRKG 131 Query: 307 LTIFPEEL---IIGRTINGTFFGGWKSVDSIPKLVTDYKN 343 ++L ++G + T+ + + I ++ T ++ Sbjct: 132 GPRTAKDLQGKVVGVQVGTTYMEAAQKIPGIKEVRTYQRD 171 >3KIZ-A nrPDB Length = 394 Score = 28.5 bits (62), Expect = 5.3, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 20/35 (57%) Query: 246 CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSET 280 L+P + P+ + II KG +D + C+GG +T Sbjct: 261 VLSPTRTYAPLMKEIIHQYKGKLDGVVHCSGGGQT 295 >3BKX-A nrPDB Length = 275 Score = 28.5 bits (62), Expect = 5.5, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 183 STGYGAAINNA-KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 T + AI A +V PG G G LSAV+ + + + GIDI S + L Sbjct: 28 QTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTL 87 Query: 242 G 242 G Sbjct: 88 G 88 >4EL1-A nrPDB Length = 482 Score = 28.5 bits (62), Expect = 5.7, Method: Compositional matrix adjust. Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 7/73 (9%) Query: 91 VIPLYAPLCRKCKFCLSPLTNLCGKI----SNLKSPASDQQLMEDKTSRFTCKGKPVYHF 146 ++ YAP C CK GK+ S ++ D D ++ +G P F Sbjct: 48 LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 107 Query: 147 F---GTSTFSQYT 156 F T++ +YT Sbjct: 108 FRNGDTASPKEYT 120 >1E3W-A nrPDB Length = 261 Score = 28.1 bits (61), Expect = 6.2, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 8/78 (10%) Query: 205 GLGGVGLSAVMGCKAAGASRIIGIDI-NSEKFVKAKALGATDCLNPRDL--HKPIQEVII 261 G G+GLS GA+ ++ +D+ NSE +AK LG P ++ K +Q + Sbjct: 18 GASGLGLSTAKRLVGQGATAVL-LDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAA-L 75 Query: 262 ELTK---GGVDFALDCAG 276 L K G +D A++CAG Sbjct: 76 TLAKEKFGRIDVAVNCAG 93 >1MEK-A nrPDB Length = 120 Score = 28.1 bits (61), Expect = 7.2, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 7/73 (9%) Query: 91 VIPLYAPLCRKCKFCLSPLTNLCGKI----SNLKSPASDQQLMEDKTSRFTCKGKPVYHF 146 ++ YAP C CK GK+ S ++ D D ++ +G P F Sbjct: 28 LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 87 Query: 147 F---GTSTFSQYT 156 F T++ +YT Sbjct: 88 FRNGDTASPKEYT 100 >1V9L-A nrPDB Length = 421 Score = 27.7 bits (60), Expect = 8.5, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 7/63 (11%) Query: 182 FSTGYGAAINNAKVT-------PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK 234 ++TG+G A+ ++ G T A+ G+G VG + GA I DIN Sbjct: 187 YATGFGVAVATREMAKKLWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVA 246 Query: 235 FVK 237 + K Sbjct: 247 YRK 249 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3COS-A nrPDB 506 e-144 1HSZ-A nrPDB 458 e-129 1HSO-A nrPDB 456 e-129 1U3W-A nrPDB 455 e-128 1E3E-A nrPDB 451 e-127 1EE2-A nrPDB 442 e-124 4DLA-A nrPDB 435 e-122 1MC5-A nrPDB 435 e-122 4JJI-A nrPDB 432 e-121 1D1T-A nrPDB 424 e-119 4RQU-A nrPDB 422 e-118 1CDO-A nrPDB 419 e-117 1P0F-A nrPDB 395 e-110 1F8F-A nrPDB 315 1e-86 3PII-A nrPDB 313 5e-86 3MEQ-A nrPDB 312 2e-85 5TNX-A nrPDB 307 6e-84 2DFV-A nrPDB 302 2e-82 1LLU-A nrPDB 300 9e-82 4Z6K-A nrPDB 299 1e-81 3S2F-A nrPDB 295 2e-80 3GFB-A nrPDB 292 2e-79 6N7L-A nrPDB 282 2e-76 5KIA-A nrPDB 275 3e-74 2DQ4-A nrPDB 273 1e-73 1PL8-A nrPDB 272 2e-73 3QE3-A nrPDB 271 3e-73 4CPD-A nrPDB 271 3e-73 5YLN-A nrPDB 267 5e-72 1YKF-A nrPDB 265 2e-71 2EER-A nrPDB 265 3e-71 3FSR-A nrPDB 264 4e-71 1E3J-A nrPDB 263 8e-71 3FPL-A nrPDB 259 1e-69 3FPC-A nrPDB 258 2e-69 1KEV-A nrPDB 258 3e-69 5VM2-A nrPDB 255 3e-68 1H2B-A nrPDB 254 6e-68 5ENV-A nrPDB 252 2e-67 4OH1-A nrPDB 246 1e-65 4ILK-A nrPDB 246 2e-65 1R37-A nrPDB 246 2e-65 4EEZ-A nrPDB 244 4e-65 4EJ6-A nrPDB 243 8e-65 5YAT-A nrPDB 242 2e-64 5K1S-A nrPDB 237 5e-63 1UUF-A nrPDB 236 2e-62 3M6I-A nrPDB 234 5e-62 2OUI-A nrPDB 233 1e-61 2H6E-A nrPDB 231 4e-61 6DKH-A nrPDB 228 3e-60 4UEJ-A nrPDB 228 3e-60 6FG0-A nrPDB 226 1e-59 4GKV-A nrPDB 220 6e-58 3UOG-A nrPDB 219 2e-57 5H82-A nrPDB 218 3e-57 3TWO-A nrPDB 212 2e-55 3IP1-A nrPDB 206 1e-53 6C49-A nrPDB 199 2e-51 1YQX-A nrPDB 195 2e-50 5Z0C-A nrPDB 195 3e-50 1WLY-A nrPDB 193 1e-49 5FI5-A nrPDB 188 4e-48 5VKT-A nrPDB 186 1e-47 3WLE-A nrPDB 183 8e-47 4OAQ-A nrPDB 180 1e-45 2DPH-A nrPDB 176 1e-44 4JLW-A nrPDB 174 6e-44 5H83-A nrPDB 173 9e-44 1KOL-A nrPDB 171 3e-43 3JYN-A nrPDB 168 4e-42 2VCY-A nrPDB 165 3e-41 1QOR-A nrPDB 158 3e-39 4DVJ-A nrPDB 137 6e-33 5A3V-A nrPDB 114 8e-26 3SLK-A nrPDB 110 1e-24 2CDC-A nrPDB 104 6e-23 Sequences not found previously or not previously below threshold: 1Q1N-A nrPDB 171 4e-43 1YB5-A nrPDB 144 7e-35 4J6F-A nrPDB 141 4e-34 3HZZ-A nrPDB 141 6e-34 2CF5-A nrPDB 141 7e-34 4RVS-A nrPDB 133 1e-31 2OBY-A nrPDB 129 3e-30 4Y1B-A nrPDB 126 1e-29 2VN8-A nrPDB 123 2e-28 4A10-A nrPDB 122 2e-28 3TQH-A nrPDB 122 2e-28 4A27-A nrPDB 121 5e-28 4IDE-A nrPDB 120 1e-27 4EYE-A nrPDB 119 3e-27 3FBG-A nrPDB 112 3e-25 2WEK-A nrPDB 111 4e-25 3B70-A nrPDB 108 4e-24 3QWB-A nrPDB 108 5e-24 2VWH-A nrPDB 105 3e-23 5LB9-A nrPDB 92 4e-19 1V3V-A nrPDB 82 3e-16 3WID-A nrPDB 80 2e-15 5GXF-A nrPDB 75 7e-14 2Y05-A nrPDB 74 1e-13 1O89-A nrPDB 69 4e-12 2J3K-A nrPDB 64 1e-10 2VNA-A nrPDB 59 3e-09 2ZB3-A nrPDB 57 2e-08 1ZCJ-A nrPDB 45 5e-05 3ZWA-A nrPDB 44 1e-04 4DIO-A nrPDB 42 3e-04 3MGG-A nrPDB 42 4e-04 2EGU-A nrPDB 41 9e-04 5ILO-A nrPDB 40 0.002 1BW9-B nrPDB 39 0.005 2VHY-A nrPDB 39 0.005 1XLT-A nrPDB 38 0.006 1X14-A nrPDB 38 0.006 1E3W-A nrPDB 38 0.007 6BII-A nrPDB 38 0.008 1I9G-A nrPDB 38 0.008 3X2F-A nrPDB 37 0.009 4XIJ-A nrPDB 37 0.014 2B25-A nrPDB 37 0.015 6C55-A nrPDB 36 0.022 5U9P-A nrPDB 36 0.024 1V9L-A nrPDB 36 0.026 3VPX-A nrPDB 36 0.030 5UYY-A nrPDB 36 0.031 1V8B-A nrPDB 36 0.033 2O23-A nrPDB 36 0.033 5EKU-A nrPDB 35 0.038 4M36-A nrPDB 35 0.038 4K2X-A nrPDB 35 0.040 3EBV-A nrPDB 35 0.041 1VH3-A nrPDB 35 0.048 5JXW-A nrPDB 35 0.064 1DXY-A nrPDB 35 0.065 1ZFN-A nrPDB 35 0.070 2HMT-A nrPDB 35 0.071 4DIM-A nrPDB 35 0.077 5BUT-A nrPDB 34 0.081 3TMA-A nrPDB 34 0.096 3LGA-A nrPDB 34 0.10 3EGI-A nrPDB 34 0.10 3GDH-A nrPDB 34 0.11 1NVM-B nrPDB 34 0.11 3KYD-B nrPDB 34 0.11 3KYC-B nrPDB 34 0.11 5Z1Z-A nrPDB 34 0.12 3OAM-A nrPDB 34 0.13 6CU3-A nrPDB 34 0.14 4N7R-A nrPDB 34 0.14 6GBN-A nrPDB 34 0.15 6FZI-A nrPDB 34 0.15 2ZJ1-A nrPDB 34 0.15 1CYD-A nrPDB 34 0.15 3CJR-A nrPDB 34 0.16 4J90-A nrPDB 34 0.16 4DIB-A nrPDB 34 0.17 3G1U-A nrPDB 33 0.17 5JE5-A nrPDB 33 0.18 3EMK-A nrPDB 33 0.18 2EKL-A nrPDB 33 0.20 1JWB-B nrPDB 33 0.20 2YVG-A nrPDB 33 0.20 1X5E-A nrPDB 33 0.21 3OND-A nrPDB 33 0.24 5VMT-A nrPDB 33 0.24 6IQV-A nrPDB 33 0.27 5T5Q-A nrPDB 33 0.28 4CUK-A nrPDB 33 0.29 4RS3-A nrPDB 32 0.31 4COO-A nrPDB 32 0.32 4GCM-A nrPDB 32 0.33 1M54-A nrPDB 32 0.33 6ACF-A nrPDB 32 0.34 5AOV-A nrPDB 32 0.35 5MMS-A nrPDB 32 0.35 2AS0-A nrPDB 32 0.37 3GRP-A nrPDB 32 0.37 4XGI-A nrPDB 32 0.39 5TQV-A nrPDB 32 0.39 5ITV-A nrPDB 32 0.40 3JTJ-A nrPDB 32 0.42 1XDW-A nrPDB 32 0.42 3N58-A nrPDB 32 0.49 4PZE-A nrPDB 32 0.50 3HWR-A nrPDB 32 0.50 1B26-A nrPDB 32 0.51 1VE9-A nrPDB 32 0.51 1WG8-A nrPDB 32 0.53 5EES-A nrPDB 32 0.55 4FS8-A nrPDB 32 0.55 5JJC-A nrPDB 32 0.60 3NJ4-A nrPDB 32 0.60 3FBT-A nrPDB 32 0.61 1W1U-A nrPDB 32 0.61 3BKX-A nrPDB 32 0.64 4K28-A nrPDB 32 0.65 4MIE-A nrPDB 31 0.74 4JZB-A nrPDB 31 0.77 1QO8-A nrPDB 31 0.77 2WWR-A nrPDB 31 0.78 1ZOD-A nrPDB 31 0.78 4IZO-A nrPDB 31 0.79 2EEZ-A nrPDB 31 0.79 2UVD-A nrPDB 31 0.80 4Q1T-A nrPDB 31 0.83 3WGE-A nrPDB 31 0.88 6J0Z-C nrPDB 31 0.88 3NT2-A nrPDB 31 0.91 4LRT-B nrPDB 31 0.95 1GPJ-A nrPDB 31 1.0 5UJU-A nrPDB 31 1.1 5ZBK-A nrPDB 31 1.1 3TNL-A nrPDB 31 1.1 1UIR-A nrPDB 31 1.1 4KIC-A nrPDB 30 1.1 2NVU-B nrPDB 30 1.2 1YOV-B nrPDB 30 1.2 1YPF-A nrPDB 30 1.2 1T5A-A nrPDB 30 1.2 4MOP-A nrPDB 30 1.2 4EJ0-A nrPDB 30 1.3 6BQ5-A nrPDB 30 1.4 3HDH-A nrPDB 30 1.5 4YRY-B nrPDB 30 1.6 2XF8-A nrPDB 30 1.6 1LSS-A nrPDB 30 1.6 3AOE-A nrPDB 30 1.6 2RIR-A nrPDB 30 1.7 3PPI-A nrPDB 30 1.8 6APH-A nrPDB 30 1.8 3H9U-A nrPDB 30 1.8 1F14-A nrPDB 30 1.8 3HM2-A nrPDB 30 1.9 6ABI-A nrPDB 30 1.9 3DC2-A nrPDB 30 1.9 6GME-A nrPDB 30 2.0 4AEC-A nrPDB 30 2.0 4XRR-A nrPDB 30 2.1 2LDB-A nrPDB 30 2.1 3ZZN-A nrPDB 30 2.1 4F86-A nrPDB 30 2.1 4C12-A nrPDB 30 2.2 4P4L-A nrPDB 30 2.3 5NMX-A nrPDB 30 2.4 3GDF-A nrPDB 30 2.4 6DLL-A nrPDB 30 2.5 3F9I-A nrPDB 30 2.5 1LTH-T nrPDB 29 2.6 3OC4-A nrPDB 29 2.6 3JTM-A nrPDB 29 2.6 5F8E-A nrPDB 29 2.6 4TXK-A nrPDB 29 2.7 2BRY-A nrPDB 29 2.7 4P8R-A nrPDB 29 2.8 4E4T-A nrPDB 29 2.8 3VZS-A nrPDB 29 2.9 5IM5-P nrPDB 29 3.0 5OHX-A nrPDB 29 3.0 5UOG-A nrPDB 29 3.1 2X36-A nrPDB 29 3.1 4RDI-A nrPDB 29 3.3 3GG9-A nrPDB 29 3.3 3MOG-A nrPDB 29 3.3 1HL3-A nrPDB 29 3.4 3OSU-A nrPDB 29 3.4 4FHN-X nrPDB 29 3.5 5TUK-A nrPDB 29 3.6 3GG2-A nrPDB 29 3.8 4X4J-A nrPDB 29 3.9 4L4S-H nrPDB 29 3.9 3X43-A nrPDB 29 4.1 2HAE-A nrPDB 29 4.1 3C3P-A nrPDB 29 4.1 5D1F-A nrPDB 29 4.5 5VJ7-A nrPDB 29 4.5 4ZGS-A nrPDB 29 4.7 6DHM-A nrPDB 29 4.7 4EIQ-A nrPDB 29 5.3 2GSX-A nrPDB 29 5.5 1CRW-G nrPDB 29 5.5 3O8N-A nrPDB 29 5.5 3RWB-A nrPDB 28 5.7 5IJZ-A nrPDB 28 6.0 2YFH-A nrPDB 28 6.0 1YB2-A nrPDB 28 6.0 2GMH-A nrPDB 28 6.0 1WY7-A nrPDB 28 6.1 4XTI-A nrPDB 28 6.2 5JFC-L nrPDB 28 6.6 4PRK-A nrPDB 28 6.6 2AG5-A nrPDB 28 6.7 1MV8-A nrPDB 28 6.8 1XJ5-A nrPDB 28 7.1 1KZH-A nrPDB 28 7.4 1NP3-A nrPDB 28 8.1 4V68-BC nrPDB 28 8.3 5J5V-A nrPDB 28 9.3 1MZJ-A nrPDB 27 9.5 3BIO-A nrPDB 27 9.9 >3COS-A nrPDB Length = 381 Score = 506 bits (1302), Expect = e-144, Method: Composition-based stats. Identities = 378/380 (99%), Positives = 380/380 (100%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 61 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 241 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 301 AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 360 AAGSKGLT+FPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 361 ISEAFDLMNQGKSVRTILIF 380 ISEAFDLMNQGKS+RTILIF Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1HSZ-A nrPDB Length = 374 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 226/378 (59%), Positives = 283/378 (74%), Gaps = 5/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IE+VEVAPPKA+EVRI+++A +C TD V+ Sbjct: 2 TAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLV-TP 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLK----NDL 116 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 + + ++D T RFTC+GKP++HF GTSTFSQYTVV + +AKID + LE+VCL+GCGF Sbjct: 117 GNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 176 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STGYG+A+N AKVTPGSTCAVFGLGGVGLSAVMGCKAAGA+RII +DIN +KF KAK LG Sbjct: 177 STGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELG 236 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 AT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 237 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 296 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 S+ L+I P L+ GRT G +GG+KS + IPKLV D+ KKF+LDAL+TH LPF+KI+ Sbjct: 297 ASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKIN 356 Query: 363 EAFDLMNQGKSVRTILIF 380 E FDL++ GKS+RT+L F Sbjct: 357 EGFDLLHSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 456 bits (1174), Expect = e-129, Method: Composition-based stats. Identities = 226/378 (59%), Positives = 280/378 (74%), Gaps = 5/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C TD V+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TP 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI+GHEAAGIVES+G GVT VKPGDKVIPL P C KC+ C +P +N C K Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSN-- 118 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 Q ++D TSRFTC+ KP++HF G STFSQYTVV + +AKID + LE+VCL+GCGF Sbjct: 119 --PQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 176 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STGYG+A+N AKVTPGSTCAVFGLGGVGLSA+MGCKAAGA+RII +DIN +KF KAK LG Sbjct: 177 STGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 236 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 AT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 237 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 296 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 S+ L++ P L+ GRT G GG+KS + +PKLV D+ KKF+LDAL+TH LPF+KI+ Sbjct: 297 DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKIN 356 Query: 363 EAFDLMNQGKSVRTILIF 380 E FDL++ GKS+RTIL+F Sbjct: 357 EGFDLLHSGKSIRTILMF 374 >1U3W-A nrPDB Length = 374 Score = 455 bits (1170), Expect = e-128, Method: Composition-based stats. Identities = 224/378 (59%), Positives = 279/378 (73%), Gaps = 5/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C +D V+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV-TP 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLK----NDL 116 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 + + ++D T RFTC GKP++HF G STFSQYTVV + +AKID + LE+VCL+GCGF Sbjct: 117 GNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 176 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STGYG+A+ AKVTPGSTCAVFGLGGVGLS VMGCKAAGA+RII +DIN +KF KAK LG Sbjct: 177 STGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELG 236 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 AT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 237 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPP 296 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 S+ L+I P L+ GRT G FGG+KS +S+PKLV D+ KKF+LDAL+T+ LPF+KI+ Sbjct: 297 DSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKIN 356 Query: 363 EAFDLMNQGKSVRTILIF 380 E FDL+ GKS+RT+L F Sbjct: 357 EGFDLLRSGKSIRTVLTF 374 >1E3E-A nrPDB Length = 376 Score = 451 bits (1161), Expect = e-127, Method: Composition-based stats. Identities = 273/379 (72%), Positives = 323/379 (85%), Gaps = 3/379 (0%) Query: 2 GTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL 61 GT+GKVIKCKAAIAW+ G PLCIEE+EV+PPKA EVRIQ+IAT +C TD D K + L Sbjct: 1 GTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKAL 60 Query: 62 AFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKS 121 FPV++GHE AGIVES+GPGVTN KPGDKVIP +AP C++CK CLSPLTNLCGK+ N K Sbjct: 61 -FPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKY 119 Query: 122 PASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCG 181 P DQ+LMED+TSRFTCKG+ +YHF G S+FSQYTVVS+ NLA++DD+ANLERVCL+GCG Sbjct: 120 PTIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCG 179 Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 FS+GYGAAIN AKVTPGSTCAVFGLG VGLSA++GCK AGASRII IDIN EKF KAKAL Sbjct: 180 FSSGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKAL 239 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 GATDCLNPR+L KP+Q+VI ELT GGVD++LDCAG ++T+KAA+DCT GWGSCT +G Sbjct: 240 GATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVG-- 297 Query: 302 AGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 A +TI ++I+GR+INGTFFGGWKSVDS+P LV+DYKNKKF+LD LVTH LPF+ I Sbjct: 298 AKVDEMTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESI 357 Query: 362 SEAFDLMNQGKSVRTILIF 380 ++A DLM +GKS+RTIL F Sbjct: 358 NDAIDLMKEGKSIRTILTF 376 >1EE2-A nrPDB Length = 373 Score = 442 bits (1137), Expect = e-124, Method: Composition-based stats. Identities = 229/378 (60%), Positives = 281/378 (74%), Gaps = 6/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C +D V+ Sbjct: 2 TAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVA-P 60 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PVI GHEAAGIVESIG GVT V+PGDKVIPL+ P C KC C P NLC LK+ Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLC-----LKNL 115 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 + + M+D TSRFTC+GKP++HF GTSTFSQYTVV +I++AKID + LE+VCL+GCGF Sbjct: 116 SMPRGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGF 175 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STGYG+A+ AKVT GSTCAVFGLGGVGLS +MGCKAAGA+RIIG+DIN +KF KAK +G Sbjct: 176 STGYGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVG 235 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 AT+C+NP+D KPIQEV+ E++ GGVDF+ + G +TM AAL C +G +GV Sbjct: 236 ATECVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPP 295 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 S+ L++ P L+ GRT G FGG+KS DS+PKLV D+ KKF LD L+TH LPF+KI+ Sbjct: 296 DSQNLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKIN 355 Query: 363 EAFDLMNQGKSVRTILIF 380 E FDL+ GKS+RTIL F Sbjct: 356 EGFDLLRSGKSIRTILTF 373 >4DLA-A nrPDB Length = 396 Score = 435 bits (1119), Expect = e-122, Method: Composition-based stats. Identities = 202/376 (53%), Positives = 265/376 (70%), Gaps = 3/376 (0%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T+G+VI CKAA+AWE KPL IE+V+VAPP+A EVR++++ T+LCHTDA K Sbjct: 20 TQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGL 79 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 FP ++GHEAAGIVES+G GVT V+PGD VIP Y CR+CKFC S TNLCGK+ ++ Sbjct: 80 FPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKV---RAA 136 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +M D+ SRF+ GKP+YHF GTSTFSQYTVV D+++AKID A LE+VCLLGCG Sbjct: 137 TGVGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGV 196 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 TG GA N AKV PGS AVFGLG VGL+ G KAAGASRIIGIDI+S+KF +AK G Sbjct: 197 PTGLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFG 256 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 T+ +NP++ +PIQ+VI++LT GGVD++ +C G M++AL+C GWG+ +GVAA Sbjct: 257 VTEFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAA 316 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + ++ P +L+ GR GT FGG+KS +P LV Y K+ +D +TH + I+ Sbjct: 317 SGQEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADIN 376 Query: 363 EAFDLMNQGKSVRTIL 378 +AFDLM+ G +R +L Sbjct: 377 KAFDLMHDGDCLRVVL 392 >1MC5-A nrPDB Length = 374 Score = 435 bits (1118), Expect = e-122, Method: Composition-based stats. Identities = 231/375 (61%), Positives = 290/375 (77%), Gaps = 4/375 (1%) Query: 4 KGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAF 63 +VIKCKAA+AWEAGKPL IEE+EVAPPKAHEVRI+IIAT++CHTDA + F Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 64 PVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPA 123 PVI+GHE AGIVES+G GVT +K GD VIPLY P C +CKFCL+P TNLC KI + Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQ--- 118 Query: 124 SDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFS 183 + LM D TSRFTCKGK + H+ GTSTFS+YTVV+DI++AKID A L++VCLLGCG S Sbjct: 119 -GKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGIS 177 Query: 184 TGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 TGYGAA+N AK+ PGS CAVFGLGGVGL+ +MGCK AGASRIIG+DIN +KF +AK GA Sbjct: 178 TGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGA 237 Query: 244 TDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAG 303 T+C+NP+D KPIQEV+IE+T GGVD++ +C G + M+AAL+ GWG +GVAA Sbjct: 238 TECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAAS 297 Query: 304 SKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISE 363 + + P +L+ GRT GT FGGWKSV+S+PKLV++Y +KK +D VTH L FD+I++ Sbjct: 298 GEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINK 357 Query: 364 AFDLMNQGKSVRTIL 378 AF+LM+ GKS+RT++ Sbjct: 358 AFELMHSGKSIRTVV 372 >4JJI-A nrPDB Length = 378 Score = 432 bits (1110), Expect = e-121, Method: Composition-based stats. Identities = 204/376 (54%), Positives = 264/376 (70%), Gaps = 3/376 (0%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T+G+VI CKAA+A+E KPL IE+V+VAPP+A EVRI+I+ T+LCHTDA K Sbjct: 2 TQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEGL 61 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 FP I+GHEAAGIVES+G GVT V+ GD VIP Y CR+CKFC S TNLCGK+ +S Sbjct: 62 FPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKV---RSA 118 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +M D+ SRF+ GKP+YHF GTSTFSQYTVV D+++AKID A L++VCLLGCG Sbjct: 119 TGVGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGV 178 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 TG GA N AKV PGS A+FGLG VGL+ G K AGASRIIGIDI+S+K+ AK G Sbjct: 179 PTGLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFG 238 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 + +NP+D KPIQEVI++LT GGVD++ +C G M+AAL+C GWG+ +GVAA Sbjct: 239 VNEFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAA 298 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + ++ P +L+ GR GT FGG+KS +P LV Y NK+ +D +TH L +I+ Sbjct: 299 SGQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEIN 358 Query: 363 EAFDLMNQGKSVRTIL 378 +AFDL+++G +R +L Sbjct: 359 KAFDLLHEGTCLRCVL 374 >1D1T-A nrPDB Length = 373 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 220/379 (58%), Positives = 272/379 (71%), Gaps = 6/379 (1%) Query: 2 GTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL 61 GT GKVIKCKAA+ WE +P IEE+EVAPPK EVRI+I+AT +C TD VI Sbjct: 1 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS- 59 Query: 62 AFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKS 121 FPVIVGHEA GIVESIG GVT VKPGDKVIPL+ P CR+C C +P NLC ++S Sbjct: 60 KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC-----IRS 114 Query: 122 PASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCG 181 + + ++ D T+RFTCKGKPV+HF TSTF++YTVV + ++AKIDD A E+VCL+GCG Sbjct: 115 DITGRGVLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCG 174 Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 FSTGYGAA+ KV PGSTC VFGLGGVGLS +MGCK+AGASRIIGID+N +KF KA A+ Sbjct: 175 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 234 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 GAT+C++P+D KPI EV+ E+T V + + G ETM AL +G+ +GV Sbjct: 235 GATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVP 294 Query: 302 AGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 +K LT P L GRT G FGG KS D +PKLVT++ KKF+LD L+TH LPF KI Sbjct: 295 PSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKI 354 Query: 362 SEAFDLMNQGKSVRTILIF 380 SE F+L+N G+S+RT+L F Sbjct: 355 SEGFELLNSGQSIRTVLTF 373 >4RQU-A nrPDB Length = 375 Score = 422 bits (1085), Expect = e-118, Method: Composition-based stats. Identities = 185/375 (49%), Positives = 253/375 (67%), Gaps = 3/375 (0%) Query: 6 KVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPV 65 ++I+CKAA+AWEAGKPL IEEVEVAPP+ HEVRI+I+ TSLCHTD ++K + FP Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 I GHEA GIVES+G GVT+++PGD V+P++ C +C+ C S +N+C L+ Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMC---DLLRINTER 118 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTG 185 ++ D SRF+ GKP+YHF GTSTFS+YTVV +AKI+ DA L++VC++ CG STG Sbjct: 119 GGMIHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTG 178 Query: 186 YGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245 GA +N AK G + A+FGLG VGL A G + AGASRIIG+D NS++F +AK G T+ Sbjct: 179 LGATLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTE 238 Query: 246 CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 C+NP+D KPIQ+VI E+T GGVD +++C G + M A +C GWG +GV + Sbjct: 239 CVNPKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDD 298 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF 365 P + RT+ GTFFG +K IP +V Y NK+ L+ +THT+PF +I++AF Sbjct: 299 AFKTHPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAF 358 Query: 366 DLMNQGKSVRTILIF 380 D M +G+S+R I+ Sbjct: 359 DYMLKGESIRCIITM 373 >1CDO-A nrPDB Length = 374 Score = 419 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 206/378 (54%), Positives = 261/378 (69%), Gaps = 5/378 (1%) Query: 3 TKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA 62 T GKVIKCKAA+AWEA KPL IEE+EV P A+E+RI+IIAT +CHTD + Sbjct: 2 TVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKDG 61 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 FPV++GHE AGIVES+GPGVT +PG+KVIPL+ C +C+FC SP TN C K +SP Sbjct: 62 FPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESP 121 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +M K +RFTCKG+ V F GTSTFSQYTVV+ I +AKID A L+ VCLLGCG Sbjct: 122 ----DVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGV 177 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 STG+GAA+N AKV PGSTCAVFGLG VGL+AVMGC +AGA RII +D+N +KF KAK G Sbjct: 178 STGFGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFG 237 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 ATD +NP D +PI +V+ ++T GGVDF+L+C G M+ AL+ GWG +G Sbjct: 238 ATDFVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVG-WT 296 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + P +LI GRT G+ FGG+K D +PK+V Y +KK LD +TH +P + ++ Sbjct: 297 DLHDVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVN 356 Query: 363 EAFDLMNQGKSVRTILIF 380 +A DLM GK +RT+L Sbjct: 357 DAIDLMKHGKCIRTVLSL 374 >1P0F-A nrPDB Length = 373 Score = 395 bits (1015), Expect = e-110, Method: Composition-based stats. Identities = 212/380 (55%), Positives = 276/380 (72%), Gaps = 7/380 (1%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60 M T GK I CKAA+AWE KPL +E + VAPPKAHEVRI+I+A+ +C +D++V+ Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 FPVI+GHEA G+VESIG GVT VKPGDKVIPL+ P C C+ C S +N C K Sbjct: 61 -KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEK----N 115 Query: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180 + LM D TSRFTC+GKP+Y+ GTSTF++YTVV+DI +AKID A LE CL+GC Sbjct: 116 DMGAKTGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGC 174 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 GF+TGYGAA+N AKVTPGSTCAVFGLGGVG SA++GCKAAGASRIIG+ + +KF KA Sbjct: 175 GFATGYGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIE 234 Query: 241 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 LGAT+CLNP+D KPI EVI E T GGVD+A++CAG ETM AL T G G +G+ Sbjct: 235 LGATECLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGL 294 Query: 301 AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 360 A+ ++ L + P L+ GR++ G+ FGG+K + + +LV DY KK N++ LV+ L D+ Sbjct: 295 ASPNERLPLDPLLLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQ 353 Query: 361 ISEAFDLMNQGKSVRTILIF 380 I++AF+L++ G+ VR+I+I+ Sbjct: 354 INKAFELLSSGQGVRSIMIY 373 >1F8F-A nrPDB Length = 371 Score = 315 bits (808), Expect = 1e-86, Method: Composition-based stats. Identities = 124/368 (33%), Positives = 188/368 (51%), Gaps = 9/368 (2%) Query: 12 AAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEA 71 AA+ G ++ +++ P+ EV ++++AT +CHTD V D K+ + P ++GHE Sbjct: 9 AAVTPCKGADFELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYP-VPLPAVLGHEG 67 Query: 72 AGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMED 131 +GI+E+IGP VT ++ GD V+ Y C KC C + C + +D + Sbjct: 68 SGIIEAIGPNVTELQVGDHVVLSY-GYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHA 126 Query: 132 KTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAIN 191 + +G HFF S+F+ Y + + N K+ D +E + LGCG TG GA IN Sbjct: 127 LCTH--DQGVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACIN 184 Query: 192 NAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRD 251 KVTP S+ +G G VGLSA++ K GAS II +DI + AK LGAT +N + Sbjct: 185 ALKVTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSK- 243 Query: 252 LHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA-GSKGLTIF 310 P+ I E+T GGV+FAL+ G E +K +D G +G G+ Sbjct: 244 TQDPVA-AIKEITDGGVNFALESTGSPEILKQGVDALGI-LGKIAVVGAPQLGTTAQFDV 301 Query: 311 PEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQ 370 + L+ G+TI G G IP+LV Y+ KF D LV FD+I++A + Sbjct: 302 NDLLLGGKTILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLVKF-YAFDEINQAAIDSRK 360 Query: 371 GKSVRTIL 378 G +++ I+ Sbjct: 361 GITLKPII 368 >3PII-A nrPDB Length = 339 Score = 313 bits (803), Expect = 5e-86, Method: Composition-based stats. Identities = 108/373 (28%), Positives = 163/373 (43%), Gaps = 41/373 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ + +PL I+EVE EV ++I A +CHTD + P+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E GIVE +GPGVT++K GD+V IP C C +CLS LC N Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNAGYSV----- 116 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 +++Y + + KI D+ + E + C T Y Sbjct: 117 --------------------DGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-K 155 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 A+ PG A++G+GG G AV KA G + ++ +DI EK AK LGA +N Sbjct: 156 ALKVTGAKPGEWVAIYGIGGFGHVAVQYAKAMGLN-VVAVDIGDEKLELAKELGADLVVN 214 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 P L + + + E GGV A+ A ++A + G G+C +G+ + Sbjct: 215 P--LKEDAAKFMKEKV-GGVHAAVVTAVSKPAFQSAYNSIRRG-GACVLVGLPPEEMPIP 270 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 IF + ++ G I G+ G K + + + K K + P +KI+E FD M Sbjct: 271 IF-DTVLNGIKIIGSIVGTRKDLQEALQFAAEGKVK------TIIEVQPLEKINEVFDRM 323 Query: 369 NQGKS-VRTILIF 380 +G+ R +L Sbjct: 324 LKGQINGRVVLTL 336 >3MEQ-A nrPDB Length = 365 Score = 312 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 97/371 (26%), Positives = 151/371 (40%), Gaps = 38/371 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ GKPL I+EV + P ++++ I A+ +CHTD + + P I GH Sbjct: 27 KAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGH 86 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G V ++G GV +VK GD+V IP C C+ CL LC + N Sbjct: 87 EGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQLNTGYSV----- 141 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 F++Y V + + + + + + C T Y Sbjct: 142 --------------------NGGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-K 180 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + PG + G+GG+G AV +A G + + +DI+ K A+ LGAT +N Sbjct: 181 GLKVTDTKPGDWVVISGIGGLGHMAVQYARAMGLN-VAAVDIDDRKLDLARRLGATVTVN 239 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 + + P I + T GG L A + + AL G G+ + G+ G L+ Sbjct: 240 AKTVADPAAY-IRKETDGGAQGVLVTAVSPKAFEQALGMVARG-GTVSLNGLPPGDFPLS 297 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 IF ++ G T+ G+ G + D K K T + I+ FD M Sbjct: 298 IFNM-VLNGVTVRGSIVGTRLDLQESLDFAADGKVKA------TIQTGKLEDINAIFDDM 350 Query: 369 NQGKSVRTILI 379 QG I++ Sbjct: 351 RQGNIEGRIVM 361 >5TNX-A nrPDB Length = 383 Score = 307 bits (786), Expect = 6e-84, Method: Composition-based stats. Identities = 128/380 (33%), Positives = 194/380 (51%), Gaps = 11/380 (2%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60 M T+ AA+A AG P IE + P+ EV ++++AT LCHTD V D + Sbjct: 9 MYTENDTRAVTAAVARAAGAPFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYP- 67 Query: 61 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 + P ++GHE AG+VE++GP V + GD V+ Y C C C C + L Sbjct: 68 VPLPAVLGHEGAGVVEAVGPNVKTLAAGDHVVLTY-GACGHCASCAGGHGAYCRQFFALN 126 Query: 121 SPASDQQLMEDKTSRFTCKGKPVY-HFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLG 179 +D + +T+ G+P++ HFF S+F+ Y + + N K+ +A LE + LG Sbjct: 127 FGGADA---DGQTALRDAAGEPLHDHFFAQSSFASYALARENNAIKVPKEAPLELLGPLG 183 Query: 180 CGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 239 CG TG GA IN+ V GS+ A FG G VG+SAVM + AGA+ II +DI + A Sbjct: 184 CGIQTGAGAVINSLAVRTGSSFASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALAL 243 Query: 240 ALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG 299 LGAT +N +++ + + I E+T GGVD+AL+ G + +D + G+ +G Sbjct: 244 ELGATHAINSKEV--DVVDAIREITGGGVDYALESTGLPAVLSQGIDALGS-RGTMGVVG 300 Query: 300 VAA-GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPF 358 G+K L+ G TI G G IP+LV + +F D LV P Sbjct: 301 APKLGTKAEFDVNSLLLGGHTIRGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLVKF-YPL 359 Query: 359 DKISEAFDLMNQGKSVRTIL 378 ++I++A + G +++ IL Sbjct: 360 EQINQAAADSSSGITLKPIL 379 >2DFV-A nrPDB Length = 347 Score = 302 bits (772), Expect = 2e-82, Method: Composition-based stats. Identities = 96/379 (25%), Positives = 161/379 (42%), Gaps = 42/379 (11%) Query: 9 KCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPV 65 K A + + G + EV+V P EV I+++ATS+C TD + + + P Sbjct: 3 KMVAIMKTKPGYGAELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQ 62 Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 I+GHE AG V IGPGV ++ GD V +C KC C ++C Sbjct: 63 IMGHEVAGEVVEIGPGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVC------------ 110 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTG 185 + ++ F++Y VV N+ K E L Sbjct: 111 -------------QNTKIFGVDTDGVFAEYAVVPAQNIWKNPKSIPPEYATL-----QEP 152 Query: 186 YGAAINNAKVTP--GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 G A++ P G + + G G +GL + KA+GA +I + + + AK +GA Sbjct: 153 LGNAVDTVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGA 212 Query: 244 TDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 +NP + + + ++++T G GVD L+ +G + ++ L T G + +G+ Sbjct: 213 DYVINP--FEEDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYP 269 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKI 361 G + + TI G G ++ + ++ K NLD ++TH FDK Sbjct: 270 GKVTIDFNNLIIFKALTIYG--ITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKY 327 Query: 362 SEAFDLMNQGKSVRTILIF 380 EAF+LM GK+ + + + Sbjct: 328 EEAFELMRAGKTGKVVFML 346 >1LLU-A nrPDB Length = 342 Score = 300 bits (767), Expect = 9e-82, Method: Composition-based stats. Identities = 93/371 (25%), Positives = 147/371 (39%), Gaps = 40/371 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ G PL IEEV+V P +V ++I A+ +CHTD + + P I GH Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGH 67 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G V ++G GVT VK GD+V IP C C+ CL+ LC N Sbjct: 68 EGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGYSV----- 122 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 +++Y + + + + + + C T Y Sbjct: 123 --------------------NGGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-K 161 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + PG A+ G+GG+G AV +A G + IDI+ K A+ LGA+ +N Sbjct: 162 GLKQTNARPGQWVAISGIGGLGHVAVQYARAMG-LHVAAIDIDDAKLELARKLGASLTVN 220 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 R P++ + ++ GG L A + A+ G G+ +G+ G Sbjct: 221 ARQ-EDPVEAIQRDI--GGAHGVLVTAVSNSAFGQAIGMARRG-GTIALVGLPPGDFPTP 276 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 IF + ++ G I G+ G + + K H D I++ D M Sbjct: 277 IF-DVVLKGLHIAGSIVGTRADLQEALDFAGEGLVKA------TIHPGKLDDINQILDQM 329 Query: 369 NQGKSVRTILI 379 G+ I++ Sbjct: 330 RAGQIEGRIVL 340 >4Z6K-A nrPDB Length = 346 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 99/371 (26%), Positives = 162/371 (43%), Gaps = 40/371 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ E G+ L IEEV++ P A E+ +++ A+ +CHTD ++ + + P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G++ ++G GVT+VK GD+V + C C CL LC N Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNSGYSV----- 116 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 +F++Y + + + I + + + + C T Y Sbjct: 117 --------------------NGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-K 155 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + PG + G+GG+G AV A G + + +DI+ +K AK LGA +N Sbjct: 156 GLKMTDTKPGDWVVISGIGGLGHMAVQYAIAMGLN-VAAVDIDDDKLAFAKKLGAKVTVN 214 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 ++ P + + E+ GG AL A ++ AL G G+ G+ G ++ Sbjct: 215 AKNT-DPAEYLQKEI--GGAHGALVTAVSAKAFDQALSMLRRG-GTLVCNGLPPGDFPVS 270 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 IF + ++ G TI G+ G + + K K A VT P + I++ F+ M Sbjct: 271 IF-DTVLNGITIRGSIVGTRLDLQESLDMAAAGKVK-----ATVTAE-PLENINDIFERM 323 Query: 369 NQGKSVRTILI 379 QGK I+I Sbjct: 324 RQGKIEGRIVI 334 >3S2F-A nrPDB Length = 340 Score = 295 bits (754), Expect = 2e-80, Method: Composition-based stats. Identities = 99/373 (26%), Positives = 150/373 (40%), Gaps = 41/373 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 KAA+ G PL I+EV V P +V+++I A+ +CHTD D + P I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E G V ++G GV+ VK GD+V +P C C+ CL LC K N Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSV----- 118 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 + +Y V + + D + + C T Y Sbjct: 119 --------------------NGGYGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-K 157 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + PG + G+GG+G AV +A G R+ +DI+ K A+ LGA +N Sbjct: 158 GLKVTDTRPGQWVVISGIGGLGHVAVQYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVN 216 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 RD P + E+ GG L A + A+ G G+ G+ G G Sbjct: 217 ARDT-DPAAWLQKEI--GGAHGVLVTAVSPKAFSQAIGMVRRG-GTIALNGLPPGDFGTP 272 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 IF + ++ G TI G+ G + ++ A V+ T D +++ F + Sbjct: 273 IF-DVVLKGITIRGSIVGTRSDLQESLDFAAHG-----DVKATVS-TAKLDDVNDVFGRL 325 Query: 369 NQGKS-VRTILIF 380 +GK R +L F Sbjct: 326 REGKVEGRVVLDF 338 >3GFB-A nrPDB Length = 350 Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats. Identities = 95/377 (25%), Positives = 166/377 (44%), Gaps = 42/377 (11%) Query: 9 KCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPV 65 K +A + + + EV+V P EV I+++ATS+C TD + + + P Sbjct: 4 KMQAIMKTKPAYGAELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQ 63 Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 I+GHE AG V +GPGV +++ GD + +C KC C ++C Sbjct: 64 IMGHEVAGEVVEVGPGVEDLQVGDYISVETHIVCGKCYACKHNRYHVC------------ 111 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTG 185 + ++ F+ Y +V N K D E L Sbjct: 112 -------------QNTKIFGVDMDGVFAHYAIVPAKNAWKNPKDMPPEYAAL-----QEP 153 Query: 186 YGAAINNAKVTP--GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 G A++ P G + + G G +GL + KA+GA +I + + + AK +GA Sbjct: 154 LGNAVDTVLAGPIAGRSTLITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGA 213 Query: 244 TDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 +NP + P++ ++++T G GV+ L+ +G + ++ L T G G + +G+ Sbjct: 214 DYVVNPFE-EDPVK-FVMDITDGAGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLFP 270 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKI 361 + +TI LII + + G ++ + + ++ K NLD ++TH FDK Sbjct: 271 --REVTIDFNNLIIFKALEVHGITGRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKF 328 Query: 362 SEAFDLMNQGKSVRTIL 378 EAF+LM GK+ + + Sbjct: 329 EEAFELMRAGKTGKVVF 345 >6N7L-A nrPDB Length = 353 Score = 282 bits (721), Expect = 2e-76, Method: Composition-based stats. Identities = 95/371 (25%), Positives = 148/371 (39%), Gaps = 41/371 (11%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG-LAFPVIVGH 69 KAA+ G+PL I+EV V P +EV ++++A +CHTD +D + P+I GH Sbjct: 15 KAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGH 74 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E GIV + GP VK GD V +P C C +C++ LC N Sbjct: 75 EGVGIVVACGPDAM-VKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSV----- 128 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 F++Y + + + + N + + C T Y Sbjct: 129 --------------------DGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-K 167 Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + + PG A+ G+GG+G AV KA G + ID+ +K AK LGA +N Sbjct: 168 GLKETETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKLELAKKLGADLTVN 226 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 + + GG+ AL A K +D G+ G+ GS L Sbjct: 227 AKTTD---PGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRK-GTIALNGLPPGSFELP 282 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 IF E ++ T+ G+ G K + + K A + I++ FD M Sbjct: 283 IF-ETVLKRITVRGSIVGTRKDLQEALDFANEGLVKATVTSA------KLEDINDVFDKM 335 Query: 369 NQGKSVRTILI 379 +G+ I++ Sbjct: 336 KKGQIDGRIVL 346 >5KIA-A nrPDB Length = 351 Score = 275 bits (702), Expect = 3e-74, Method: Composition-based stats. Identities = 80/372 (21%), Positives = 144/372 (38%), Gaps = 39/372 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIV 67 KA E G L + V+ ++V I+I T++C TD + + P+ V Sbjct: 10 KALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHV 69 Query: 68 GHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQ 127 GHE G + +G V GD+V C C+ C + +LC + Sbjct: 70 GHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVN----- 124 Query: 128 LMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYG 187 F++Y + N KI + + + + F Sbjct: 125 --------------------REGAFAEYLAIPAFNAFKIPPEISDDLAA-IFDPFGNATH 163 Query: 188 AAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 A++ V G + G G +G+ AV K GA ++ DIN + A+ +GAT + Sbjct: 164 TALSFNLV--GEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAV 221 Query: 248 NPRDLHKPIQEVIIEL-TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 N + +++V+ +L G D L+ +G + L+ G G +G+ Sbjct: 222 NVS--RESLRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHG-GKVALLGIPPAQTA 278 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 + + + + G I G + G + ++ K+V ++ +L ++TH D + F Sbjct: 279 ID-WNQVIFKGLEIKGIY--GREMFETWYKMVAMLQSG-LDLSPIITHRFAVDDYEKGFA 334 Query: 367 LMNQGKSVRTIL 378 M G+S + IL Sbjct: 335 AMLSGESGKVIL 346 >2DQ4-A nrPDB Length = 343 Score = 273 bits (697), Expect = 1e-73, Method: Composition-based stats. Identities = 90/377 (23%), Positives = 154/377 (40%), Gaps = 44/377 (11%) Query: 8 IKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFP 64 ++ A +A E G L + + V P E+ +++ A S+C TD + + P Sbjct: 1 MRALAKLAPEEG--LTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPP 58 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 ++ GHE +G+VE++GPGV + GD V +C C C + ++C L Sbjct: 59 LVTGHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGVD-- 116 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFST 184 F++Y VV N D E +L Sbjct: 117 -----------------------RDGGFAEYVVVPAENAWVNPKDLPFEVAAILE----- 148 Query: 185 GYGAAINNAKVT---PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 +G A++ G + + G G +GL A M +A+GA I+ D N + A+ Sbjct: 149 PFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY 208 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 A +NP L + + EV+ +T GV+ L+ +G + L G G +G+ Sbjct: 209 -ADRLVNP--LEEDLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIPG-GEARILGIP 264 Query: 302 AGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 + + E ++ G T G G + + + + + +L L+TH LP + Sbjct: 265 SDPIRFDLAGELVMRGITAFG--IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRY 322 Query: 362 SEAFDLMNQGKSVRTIL 378 EAF L+ G++V+ IL Sbjct: 323 REAFGLLASGQAVKVIL 339 >1PL8-A nrPDB Length = 356 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 84/364 (23%), Positives = 156/364 (42%), Gaps = 36/364 (9%) Query: 19 GKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIV 75 L +E + P +EV +++ + +C +D + G + P+++GHEA+G V Sbjct: 16 PGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTV 75 Query: 76 ESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSR 135 E +G V ++KPGD+V +FC NL I +P D L Sbjct: 76 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL------- 128 Query: 136 FTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKV 195 F+ + Y K+ D+ E L+ S G A V Sbjct: 129 --------CRFYKHNAAFCY---------KLPDNVTFEEGALIE-PLSVGIHAC-RRGGV 169 Query: 196 TPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN-PRDLHK 254 T G V G G +G+ ++ KA GA++++ D+++ + KAK +GA L ++ + Sbjct: 170 TLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQ 229 Query: 255 PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL 314 I + + ++C G +++A + T +G G+ +G+ + +T P Sbjct: 230 EIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GTLVLVGLGS---EMTTVPLLH 285 Query: 315 IIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSV 374 R ++ G ++ ++ P ++ +K N+ LVTH P +K EAF+ +G + Sbjct: 286 AAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 343 Query: 375 RTIL 378 + +L Sbjct: 344 KIML 347 >3QE3-A nrPDB Length = 355 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 84/364 (23%), Positives = 158/364 (43%), Gaps = 36/364 (9%) Query: 19 GKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIV 75 L +E + P +EV +++ + +C +D G + P+++GHEA+G V Sbjct: 15 PGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTV 74 Query: 76 ESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSR 135 +G V +++PGD+V + +FC NL I +P D L Sbjct: 75 VKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATPPDDGNL------- 127 Query: 136 FTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKV 195 F+ + Y K+ D+ E L+ S G A A V Sbjct: 128 --------CRFYKHNANFCY---------KLPDNVTFEEGALIE-PLSVGIHAC-RRAGV 168 Query: 196 TPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN-PRDLHK 254 T G+ V G G +GL ++ KA GA++++ D+++ + KAK +GA L + + Sbjct: 169 TLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPE 228 Query: 255 PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL 314 I + + L + ++C G +++A + T +G G+ +G+ + +T P Sbjct: 229 EIAKKVEGLLGSKPEVTIECTGVETSIQAGIYATHSG-GTLVLVGLGS---EMTSVPLVH 284 Query: 315 IIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSV 374 R ++ G ++ ++ P ++ +K N+ LVTH P +K EAF+ +G + Sbjct: 285 AATREVD--IKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGL 342 Query: 375 RTIL 378 + ++ Sbjct: 343 KVMI 346 >4CPD-A nrPDB Length = 347 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 91/371 (24%), Positives = 165/371 (44%), Gaps = 33/371 (8%) Query: 13 AIAWEAGKPLCIEEVEVAPPK-AHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEA 71 A+ +E + + ++EV + + +++ +C +D + K L ++GHE Sbjct: 3 AVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLP-GSVLGHEF 61 Query: 72 AGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMED 131 G VE++G G+ +++PGD V+ + C C +C NLC + L Sbjct: 62 VGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNL--- 118 Query: 132 KTSRFTCKGKPVYHFFGTSTFSQYTVVS--DINLAKIDDDANLERVCLLGCGFSTGYGAA 189 ++ V ++NL K+ + + ER G ST YG Sbjct: 119 -----------------QGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGL 161 Query: 190 INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNP 249 I ++ PG + AV G G VGL A+ + GAS+I+ ID E+ +A +LGA +N Sbjct: 162 IQ-GQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INA 219 Query: 250 RDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTI 309 + P++ V E G D L+ GG+ T+ AL+ G G + +GV Sbjct: 220 -EQENPVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPG-GRVSAVGV----DNAPS 273 Query: 310 FPEELIIGRTINGTFFGGWKSVD-SIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 FP L G + TF G +V I ++ + + + +V+H LP ++ ++L Sbjct: 274 FPFPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELF 333 Query: 369 NQGKSVRTILI 379 ++ ++++ +L+ Sbjct: 334 DRKEALKVLLV 344 >5YLN-A nrPDB Length = 356 Score = 267 bits (683), Expect = 5e-72, Method: Composition-based stats. Identities = 97/372 (26%), Positives = 159/372 (42%), Gaps = 36/372 (9%) Query: 15 AWEAGKPLCIEEVEVAPP---KAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEA 71 A+ KP V+V P K + ++I+ T++C TD +I I+GHE Sbjct: 7 AYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEG 66 Query: 72 AGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMED 131 GIVE +G GV+N K GDKV+ C KC +C + C Sbjct: 67 IGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCED---------------- 110 Query: 132 KTSRFTCKGKPVYHFFGTSTFSQYTVVS--DINLAKIDDDANLERVCLLGCGFSTGYGAA 189 +G ++ ++Y V D L +D + E + +L TGY Sbjct: 111 -------EGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIG 163 Query: 190 INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNP 249 + KV PG + A+ G G VGL+A++ + +++I +D++ + A + GAT +N Sbjct: 164 VLKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNS 223 Query: 250 RDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 D K I+E I +LT G GVD A++ G T G+ GV Sbjct: 224 SDPEKAIKE-IYDLTDGRGVDVAIEAVGIPATFDFCQKIIGV-DGTVANCGVHGKPVEFD 281 Query: 309 IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 + + R IN T G S ++ P+L+ ++ K + LVTH +I +A+++ Sbjct: 282 LDK---LWIRNINVT--TGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVF 336 Query: 369 NQGKSVRTILIF 380 ++ I + Sbjct: 337 SKAADHHAIKVI 348 >1YKF-A nrPDB Length = 352 Score = 265 bits (678), Expect = 2e-71, Method: Composition-based stats. Identities = 100/367 (27%), Positives = 157/367 (42%), Gaps = 39/367 (10%) Query: 24 IEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVT 83 E E P + ++ +A + C +D + G +I+GHEA G V +G V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 84 NVKPGDK-VIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKP 142 + KPGD+ V+P P R + + G ++ K Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWK---------------------- 111 Query: 143 VYHFFGTSTFSQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGST 200 + F ++ V +D+NLA + + LE ++ +TG+ A A + G+T Sbjct: 112 -FSNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGAT 169 Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI 260 AV G+G VGL AV G K GA RII + AK GATD +N +D PI+ I Sbjct: 170 VAVLGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQI 227 Query: 261 IELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG-- 317 + LT+G GVD A+ G ++ M A+ G G+ + + L + E G Sbjct: 228 MNLTEGKGVDAAIIAGGNADIMATAVKIVKPG-GTIANVNYFGEGEVLPVPRLEWGCGMA 286 Query: 318 -RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQGKS-- 373 +TI G G + + +L+ K+ + LVTH FD I +AF LM Sbjct: 287 HKTIKGGLCPGGRL--RMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDL 344 Query: 374 VRTILIF 380 ++ ++I Sbjct: 345 IKPVVIL 351 >2EER-A nrPDB Length = 347 Score = 265 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 89/379 (23%), Positives = 138/379 (36%), Gaps = 44/379 (11%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE--------GLA 62 +A E GKPL +E++ + PK +V I+I A +CH+D + +F G+ Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PV +GHE AG +E +G V GD V C +C +LC L Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLCDSPRWLGIN 121 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +++Y +V + L C Sbjct: 122 Y-------------------------DGAYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSG 156 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGG-VGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 T Y A + A + P T V G GG +G A+ KA + IIG+D+ E AK Sbjct: 157 VTTYRA-VRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRA 215 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 GA +N P+ E+ G D +D +T+ + A G +G+ Sbjct: 216 GADYVINASS-QDPVSEIRRITQGKGADAVIDLNNSEKTL-SIYPYVLAKQGKYVMVGLF 273 Query: 302 AGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 P + G+ G I L K K +VT T+ ++ Sbjct: 274 GADLKY-HAPLITLNEVQFIGSLVGNQSDFLGIMSLAEAGKVK-----PMVTKTMKLEEA 327 Query: 362 SEAFDLMNQGKS-VRTILI 379 +EA D + K+ R +L+ Sbjct: 328 NEAIDNLENFKAVGRQVLV 346 >3FSR-A nrPDB Length = 352 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 101/367 (27%), Positives = 156/367 (42%), Gaps = 39/367 (10%) Query: 24 IEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVT 83 E E P + ++ +A + C +D + G +I+GHEA G V +G V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 84 NVKPGDK-VIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKP 142 + KPGD+ V+P P R + + G ++ K Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWK---------------------- 111 Query: 143 VYHFFGTSTFSQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGST 200 + F ++ V +D+NLA + + LE ++ +TG+ A A + GS+ Sbjct: 112 -FSNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSS 169 Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI 260 V G+G VGL + G K GA RIIG+ AK GATD LN ++ H I + + Sbjct: 170 VVVIGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGH--IVDQV 227 Query: 261 IELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG-- 317 ++LT G GVD + GGSET+ A+ G G + I L I E G Sbjct: 228 MKLTNGKGVDRVIMAGGGSETLSQAVSMVKPG-GIISNINYHGSGDALLIPRVEWGCGMA 286 Query: 318 -RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQGKS-- 373 +TI G G + + +L+ K+ + LVTH FD I +AF LM Sbjct: 287 HKTIKGGLCPGGRL--RMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDL 344 Query: 374 VRTILIF 380 ++ ++I Sbjct: 345 IKPVVIL 351 >1E3J-A nrPDB Length = 352 Score = 263 bits (672), Expect = 8e-71, Method: Composition-based stats. Identities = 85/374 (22%), Positives = 159/374 (42%), Gaps = 42/374 (11%) Query: 13 AIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGH 69 A+ ++ L +E+ + PK EV +Q+ +C +D + + P+++GH Sbjct: 8 AVLYKQND-LRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIGH 66 Query: 70 EAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLM 129 EA+G V +G V ++K GD+V CR+C+FC NLC ++ +P D L Sbjct: 67 EASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDDGNL- 125 Query: 130 EDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAA 189 ++Y V + K+ D+ +LE LL S G A Sbjct: 126 -----------------------ARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGVHAC 161 Query: 190 INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD--CL 247 A V G+T V G G +GL +V+ KA GA ++ + + AK GA + Sbjct: 162 -RRAGVQLGTTVLVIGAGPIGLVSVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVV 219 Query: 248 NP-RDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 +P ++ I E I + +DC+G + + ++ T G G+ +G+ + Sbjct: 220 DPAKEEESSIIERIRSAIGDLPNVTIDCSGNEKCITIGINITRTG-GTLMLVGMGSQ--- 275 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 + P R I+ ++ + P + + + N+ LVTH+ ++ +AF+ Sbjct: 276 MVTVPLVNACAREID--IKSVFRYCNDYPIALEMVASGRCNVKQLVTHSFKLEQTVDAFE 333 Query: 367 LMNQG--KSVRTIL 378 + +++ ++ Sbjct: 334 AARKKADNTIKVMI 347 >3FPL-A nrPDB Length = 351 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 104/371 (28%), Positives = 157/371 (42%), Gaps = 39/371 (10%) Query: 20 KPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIG 79 L E E +++ ++ +A S C +D + G +I+GHEA G V +G Sbjct: 10 NKLGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVG 69 Query: 80 PGVTNVKPGDKVI-PLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138 V + KPGD+VI P P R + + G ++ K Sbjct: 70 SEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWK------------------ 111 Query: 139 KGKPVYHFFGTSTFSQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVT 196 + F F +Y V +D+NLA + D LE ++ +TG+ A A + Sbjct: 112 -----FSNFKDGVFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIE 165 Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 G+T AV G+G VGL AV G K GA RII + AK GATD +N +D PI Sbjct: 166 LGATVAVLGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPI 223 Query: 257 QEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELI 315 + I+ LT+G GVD A+ G ++ M A+ G G+ + + L + E Sbjct: 224 ESQIMNLTEGKGVDAAIIAGGNADIMATAVKIVKPG-GTIANVNYFGEGEVLPVPRLEWG 282 Query: 316 IG---RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQG 371 G +TI G G + + + + +L LVTH FD I EA LM Sbjct: 283 CGMAHKTIKGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 Query: 372 KS--VRTILIF 380 ++ ++I Sbjct: 341 PKDLIKAVVIL 351 >3FPC-A nrPDB Length = 352 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 90/367 (24%), Positives = 145/367 (39%), Gaps = 39/367 (10%) Query: 24 IEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVT 83 E E P + ++ +A + C +D + G +I+GHEA G V +G V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 84 NVKPGDK-VIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKP 142 + KPGD+ V+P P R + + G ++ K Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWK---------------------- 111 Query: 143 VYHFFGTSTFSQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGST 200 + F ++ V +D+NLA + + LE ++ +TG+ A A + G T Sbjct: 112 -FSNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDT 169 Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI 260 V G+G VGL +V G GA RI + A GATD +N ++ I E I Sbjct: 170 VCVIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN--GDIVEQI 227 Query: 261 IELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG-- 317 ++ T G GVD + G T A+ G + + I E +G Sbjct: 228 LKATDGKGVDKVVIAGGDVHTFAQAVKMIKPGS-DIGNVNYLGEGDNIDIPRSEWGVGMG 286 Query: 318 -RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQGKS-- 373 + I+G G + + +L+ K+ + LVTH FD I +AF LM Sbjct: 287 HKHIHGGLCPGGRL--RMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDL 344 Query: 374 VRTILIF 380 ++ ++I Sbjct: 345 IKPVVIL 351 >1KEV-A nrPDB Length = 351 Score = 258 bits (659), Expect = 3e-69, Method: Composition-based stats. Identities = 105/371 (28%), Positives = 156/371 (42%), Gaps = 39/371 (10%) Query: 20 KPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIG 79 L E E +++ ++ +A S C +D + G +I+GHEA G V +G Sbjct: 10 NKLGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVG 69 Query: 80 PGVTNVKPGDKVI-PLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138 V + KPGD+VI P P R + + G ++ K Sbjct: 70 SEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWK------------------ 111 Query: 139 KGKPVYHFFGTSTFSQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVT 196 + F F +Y V +D+NLA + D LE ++ +TG+ A A + Sbjct: 112 -----FSNFKDGVFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQ 165 Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 GS+ V G+G VGL + G K GA RIIG+ AK GATD LN ++ H I Sbjct: 166 MGSSVVVIGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGH--I 223 Query: 257 QEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELI 315 + +++LT G GVD + GGSET+ A+ G G + I L I E Sbjct: 224 VDQVMKLTNGKGVDRVIMAGGGSETLSQAVSMVKPG-GIISNINYHGSGDALLIPRVEWG 282 Query: 316 IG---RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQG 371 G +TI G G + + + + +L LVTH FD I EA LM Sbjct: 283 CGMAHKTIKGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 Query: 372 KS--VRTILIF 380 ++ ++I Sbjct: 341 PKDLIKAVVIL 351 >5VM2-A nrPDB Length = 347 Score = 255 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 81/359 (22%), Positives = 144/359 (40%), Gaps = 41/359 (11%) Query: 14 IAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVID-SKFEGLAFP---VIVGH 69 + + I E+ PK EV I++ +C +D + F P + +GH Sbjct: 6 AILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGH 65 Query: 70 EAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLM 129 E AG V ++G V KPGD+V C C++CL N+C + + + + + Sbjct: 66 ECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYR--- 122 Query: 130 EDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAA 189 + Y + K+ D+ + L+ + G AA Sbjct: 123 --------------------GALTHYLCHPESFTYKLPDNMDTMEGTLVEPA-AVGMHAA 161 Query: 190 INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN- 248 + A V PG + G G +GL + CK GA+ I +D+ ++ A+ LGAT +N Sbjct: 162 M-LADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVING 220 Query: 249 -PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 D Q+ ++ G D + AG + T+K A G G +G G+ + Sbjct: 221 AKEDTIARCQQFTEDM---GADIVFETAGSAVTVKQAPYLVMRG-GKIMIVGTVPGASAI 276 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 L I R + T ++ + P + + +F++ ++VTH + + +AF+ Sbjct: 277 NF----LKINREV--TIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >1H2B-A nrPDB Length = 359 Score = 254 bits (648), Expect = 6e-68, Method: Composition-based stats. Identities = 90/385 (23%), Positives = 155/385 (40%), Gaps = 51/385 (13%) Query: 7 VIKCKAAIAWEAGKPLCIEEVEVAPP-KAHEVRIQIIATSLCHTDATVIDSKFEG---LA 62 V + KAA E KPL IE+V+ +V ++I +CHTD ++ + Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 P +GHE G +E + GV ++ GD VI A C C + C + Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLN 132 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERV---CLLG 179 F+++ S ++ K+ D + E++ L Sbjct: 133 I-------------------------DGGFAEFMRTSHRSVIKLPKDISREKLVEMAPLA 167 Query: 180 CGFSTGYGAAINNAK-VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA 238 T Y A A+ + PG+ A+ G+GG+G AV K + +I +D+ EK A Sbjct: 168 DAGITAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLA 227 Query: 239 KALGATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTF 297 + LGA ++ R P+++ ++ELT+G GV+ A+D G T+ G Sbjct: 228 ERLGADHVVDAR--RDPVKQ-VMELTRGRGVNVAMDFVGSQATVDYT-PYLLGRMGRLII 283 Query: 298 IGVAAGSKGLTIFPEELIIGRTI--NGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHT 355 +G FP +I + G+ G + + LVT K ++ + Sbjct: 284 VGYGGE----LRFPTIRVISSEVSFEGSLVGNYVELHE---LVTLALQGKVRVEVDI--- 333 Query: 356 LPFDKISEAFDLMNQGKS-VRTILI 379 D+I++ + + +G+ R +LI Sbjct: 334 HKLDEINDVLERLEKGEVLGRAVLI 358 >5ENV-A nrPDB Length = 347 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 80/372 (21%), Positives = 146/372 (39%), Gaps = 38/372 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVIVGH 69 K I +E+ L +++ V PKA+E+ I + + +CHTD + + P++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E AG+V +G V K GD I C C++C + C Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHAD----------- 115 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 + + +F QY + A I +L +V + C T Y Sbjct: 116 --------------LSGYTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-K 160 Query: 189 AINNAKVTPGSTCAVFG-LGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 A+ +A + G A+ G GG+G AV KA G R++GID K +++G + Sbjct: 161 ALKSANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFI 219 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 + K I +++ T GG ++ + ++A+ A G+ +G+ AG+K Sbjct: 220 DFTK-EKDIVGAVLKATDGGAHGVINVSVSEAAIEASTRYVRA-NGTTVLVGMPAGAKCC 277 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 + +++ +I G++ G K + + E ++ Sbjct: 278 SDVFNQVVKSISIVGSYVGNRADTREALDFFARGLVKSP------IKVVGLSTLPEIYEK 331 Query: 368 MNQGKSVRTILI 379 M +G+ V ++ Sbjct: 332 MEKGQIVGRYVV 343 >4OH1-A nrPDB Length = 351 Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 82/365 (22%), Positives = 141/365 (38%), Gaps = 50/365 (13%) Query: 24 IEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA------FPVIVGHEAAGIVES 77 + E + PK E+RI+++ S+C +D ++ + P+ GHE +G+++ Sbjct: 23 MMEAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVIDK 82 Query: 78 IGPGVTN--VKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSR 135 +G K G KV+ YA C C+ C NLC + Sbjct: 83 VGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMG------------------ 124 Query: 136 FTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKV 195 + + FS+Y V + I DDA+L+ L+ T ++ AK+ Sbjct: 125 -----------YRMNGFSEYAVYHMSQIFPIPDDADLKDYALVE--PLTVALSSAEQAKI 171 Query: 196 TPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKP 255 + G + A+ G GG+G+ V + AGAS I DI EK A GA LN + + Sbjct: 172 SYGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EG 229 Query: 256 IQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFP--EE 313 + E IEL G D L+ G + K L G + + L + + Sbjct: 230 VAERAIELAGGRYDCVLEGTGATAAAKLGLQLLAR-DGDAVYFAMYGKDPILPVNLQSDL 288 Query: 314 LIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKS 373 + I+G G W+ PK + + + ++ +AF+ + K Sbjct: 289 YWDQKHIHGMIQGAWQ----FPKSIRMIP--RMDFSKIIQKEHTLTNYKQAFEDLYSKKY 342 Query: 374 VRTIL 378 + ++ Sbjct: 343 AKIVI 347 >4ILK-A nrPDB Length = 359 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 80/377 (21%), Positives = 144/377 (38%), Gaps = 47/377 (12%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHE 70 +I E L I E E+ P A EVR+++ +C +D+ + +P ++GHE Sbjct: 21 MKSILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHE 80 Query: 71 AAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLME 130 G+++++G GV + + G++V C C C N+C ++ L Sbjct: 81 FFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGV--------- 131 Query: 131 DKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLG----CGFSTGY 186 FS+Y VV N KI + + ++ TG+ Sbjct: 132 ----------------HADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGH 175 Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCK-AAGASRIIGIDINSEKFVKAKALGATD 245 G N T V+G G +GL+ V K +I D E+ KAK GA Sbjct: 176 GQPTEN------DTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADW 229 Query: 246 CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 +N + P+ E E +D A +K A+ + +G ++ Sbjct: 230 AIN--NSQTPLGESFAE-KGIKPTLIIDAACHPSILKEAVTLASPA-ARIVLMGFSSEPS 285 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF 365 + ++ I G+ + + F + + P ++ + L+THT F +++A Sbjct: 286 EVI---QQGITGKEL--SIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAI 340 Query: 366 DL--MNQGKSVRTILIF 380 L ++Q + +L F Sbjct: 341 SLFELDQKHCCKVLLTF 357 >1R37-A nrPDB Length = 347 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 93/381 (24%), Positives = 142/381 (37%), Gaps = 48/381 (12%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE--------GLA 62 +A E GKPL ++E+ V PK +V I++ A +CH+D + +F G+ Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 63 FPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSP 122 PV +GHE AG +E +G V GD V C +C +LC L Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWLGIN 121 Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGF 182 +++Y +V N L C Sbjct: 122 F-------------------------DGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSG 156 Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGL-SAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 T Y A + A + P T V G GG AV KA + IIG+D+ E AK Sbjct: 157 ITTYRA-VRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRA 215 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 GA +N + P+ E+ GVD +D +T+ + A G +G+ Sbjct: 216 GADYVINAS-MQDPLAEIRRITESKGVDAVIDLNNSEKTL-SVYPKALAKQGKYVMVGLF 273 Query: 302 AGSKGLTIFPEELIIGRTIN--GTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFD 359 + LI I G+ G I +L K K ++T T+ + Sbjct: 274 GAD---LHYHAPLITLSEIQFVGSLVGNQSDFLGIMRLAEAGKVK-----PMITKTMKLE 325 Query: 360 KISEAFDLMNQGKSV-RTILI 379 + +EA D + K++ R +LI Sbjct: 326 EANEAIDNLENFKAIGRQVLI 346 >4EEZ-A nrPDB Length = 348 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 87/372 (23%), Positives = 148/372 (39%), Gaps = 40/372 (10%) Query: 12 AAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEA 71 A + + E E+ K +E + + +CHTD V F G ++GHE Sbjct: 4 AVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDF-GNKAGTVLGHEG 62 Query: 72 AGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLME 130 GIV+ IG V++++ GD+V + + C C++C+S C ++ N Sbjct: 63 IGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKNAGYSV------- 115 Query: 131 DKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAI 190 ++ +V K+ D + + C T Y AI Sbjct: 116 ------------------DGGMAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTY-KAI 156 Query: 191 NNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR 250 + V PG +FG GG+G A+ K +++I +DIN +K AK +GA +N Sbjct: 157 KVSGVKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSG 216 Query: 251 DLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTI 309 D+ P+ E I ++T G GV A+ CA + A+ G + V L+ Sbjct: 217 DV-NPVDE-IKKITGGLGVQSAIVCAVARIAFEQAVASLKP-MGKMVAVAVPNTEMTLS- 272 Query: 310 FPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMN 369 P + G + G+ G + + + K K + T ++I++ D M Sbjct: 273 VPTVVFDGVEVAGSLVGTRLDLAEAFQFGAEGKVKP------IVATRKLEEINDIIDEMK 326 Query: 370 QGK-SVRTILIF 380 GK R ++ F Sbjct: 327 AGKIEGRMVIDF 338 >4EJ6-A nrPDB Length = 370 Score = 243 bits (621), Expect = 8e-65, Method: Composition-based stats. Identities = 81/383 (21%), Positives = 155/383 (40%), Gaps = 38/383 (9%) Query: 1 MGTKGKVIKCK-AAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE 59 +GT+ + A+ E+ + + V + P ++ +++ A +C TD ++ +F Sbjct: 13 LGTENLYFQSMMKAVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFP 72 Query: 60 GLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNL 119 PV +GHE GIV G V ++ PG ++ C +C C + NLC + + Sbjct: 73 STP-PVTLGHEFCGIVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAI 131 Query: 120 KSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLG 179 F++Y +V +I L+ V Sbjct: 132 G-------------------------IHRDGGFAEYVLVPRKQAFEIP--LTLDPVHGAF 164 Query: 180 CGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 239 C ++ + + GST A+ G G +GL V + AGA+ +I + K A+ Sbjct: 165 CEPLACCLHGVDLSGIKAGSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAE 224 Query: 240 ALGATDCLNPR--DLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTF 297 +GAT ++P D+ + I + L GGVD ++CAG +ET+K + AG G+ Sbjct: 225 EVGATATVDPSAGDVVEAIAGPV-GLVPGGVDVVIECAGVAETVKQSTRLAKAG-GTVVI 282 Query: 298 IGVAAGSKGLTIFPEELIIG-RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTL 356 +GV + + I P +++ + G+F + + +D +++ + Sbjct: 283 LGVLPQGEKVEIEPFDILFRELRVLGSFINPFVHR----RAADLVATGAIEIDRMISRRI 338 Query: 357 PFDKISEAFDLMNQGKSVRTILI 379 D+ + V+ ++I Sbjct: 339 SLDEAPDVISNPAAAGEVKVLVI 361 >5YAT-A nrPDB Length = 350 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 82/372 (22%), Positives = 147/372 (39%), Gaps = 38/372 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL-AFPVIVGH 69 KA I G PL +++ V PK++E+ I + + +CHTD + P++ GH Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGGH 69 Query: 70 EAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 E AG+V + G VT + GD I C C++C+ + C K Sbjct: 70 EGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKAD----------- 118 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 + F +F QY A+I +A+L V + C T Y Sbjct: 119 --------------LSGFTHDGSFQQYATADATQAARIPKEADLAEVAPILCAGITVY-K 163 Query: 189 AINNAKVTPGSTCAV-FGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 A+ A + G A+ GG+G AV KA G R++GID ++K K+LGA + Sbjct: 164 ALKTADLRIGQWVAISGAGGGLGSLAVQYAKALG-LRVLGIDGGADKGEFVKSLGAEVFV 222 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 + + E + +LT GG ++ + + ++ G +G+ +G+ Sbjct: 223 DFTKTKDVVAE-VQKLTNGGPHGVINVSVSPHAINQSVQYVRT-LGKVVLVGLPSGAVVN 280 Query: 308 TIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDL 367 + ++ I G++ G + L T K + ++++ ++ Sbjct: 281 SDVFWHVLKSIEIKGSYVGNREDSAEAIDLFTRGLVKAP------IKIIGLSELAKVYEQ 334 Query: 368 MNQGKSVRTILI 379 M G + ++ Sbjct: 335 MEAGAIIGRYVV 346 >5K1S-A nrPDB Length = 362 Score = 237 bits (605), Expect = 5e-63, Method: Composition-based stats. Identities = 85/374 (22%), Positives = 137/374 (36%), Gaps = 39/374 (10%) Query: 11 KAAIAWEAGK--PLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVG 68 KA + G+ L +E + + P EV +++ A +C+ D + P I+G Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 69 HEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 HEAAG V +GP K GD+ L C C C S +LC + Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDN----------- 127 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA 188 + ++Q+ V L ++ + C T Sbjct: 128 -------------RFFGEELPGGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHT 174 Query: 189 AINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 KV G T + G GGVGLS+V + GA R+I + + K K GA + + Sbjct: 175 VRTRGKVRAGETVLITGASGGVGLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVI 233 Query: 248 NPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 R L + + T+G GVD A++ G T L G G +G Sbjct: 234 VSRGL--DFASDVRKRTQGAGVDVAVEIVGS-ATFDQTLKSMAPG-GRVVVVGNLESGMV 289 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEA-F 365 ++ I G + +D +L ++F VT +P + ++A F Sbjct: 290 QLNPGLVIVKELEILGAYATTQAELDEALRLTATGGVRQF-----VTDAVPLAEAAKAHF 344 Query: 366 DLMNQGKSVRTILI 379 L N+ + R +L+ Sbjct: 345 RLENREVAGRLVLV 358 >1UUF-A nrPDB Length = 369 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 84/374 (22%), Positives = 144/374 (38%), Gaps = 34/374 (9%) Query: 8 IKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIV 67 +K KA A+ A +PL ++ P ++V+I+I +CH+D + S++ G +P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 68 GHEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 GHE G V ++G V PGD V + C+ C+ C L N C ++ + + Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPD 140 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKID-DDANLERVCLLGCGFSTG 185 + +SQ VV + + +I L V L C T Sbjct: 141 EPGHT-----------------LGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITT 183 Query: 186 YGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245 Y + + + PG V G+GG+G + A GA ++ + K AKALGA + Sbjct: 184 YSP-LRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGA-HVVAFTTSEAKREAAKALGADE 241 Query: 246 CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK 305 +N R+ + + DF L+ + G+ T +G A Sbjct: 242 VVNSRNADEMAAHL------KSFDFILNTVAAPHNLDDFTTLLKR-DGTMTLVGAPATPH 294 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAF 365 ++ R I G+ GG + + D + D+I+EA+ Sbjct: 295 KSPEVFNLIMKRRAIAGSMIGGIPETQEM---LDFCAEHGIVAD---IEMIRADQINEAY 348 Query: 366 DLMNQGKSVRTILI 379 + M +G +I Sbjct: 349 ERMLRGDVKYRFVI 362 >3M6I-A nrPDB Length = 363 Score = 234 bits (597), Expect = 5e-62, Method: Composition-based stats. Identities = 79/368 (21%), Positives = 149/368 (40%), Gaps = 42/368 (11%) Query: 15 AWEAGKPLCIEEVEVAP-PKAHEVRIQIIATSLCHTDATVIDSKFEGLAF---PVIVGHE 70 W + +E V+ K EV + + +T +C +D G ++GHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 71 AAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLME 130 +AG V ++ P V ++K GD+V +C C+ CL+ N C ++ L +P L Sbjct: 80 SAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLL-- 137 Query: 131 DKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAI 190 R+ H G ++ ++ +++A A + Sbjct: 138 ---RRYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGL 172 Query: 191 NNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR 250 A V G + G G +GL ++ KAAGA ++ DI+ + AK + + + + Sbjct: 173 QRAGVRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEI-CPEVVTHK 231 Query: 251 DLHKPIQEVIIEL--TKGGVD--FALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 +E ++ + GG++ AL+C G ++ AA+ G G IGV Sbjct: 232 VERLSAEESAKKIVESFGGIEPAVALECTGVESSIAAAIWAVKFG-GKVFVIGVGKNEIQ 290 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 + + R ++ F ++ ++ P+ + +N +L LVTH P + +AF+ Sbjct: 291 IPFMRASV---REVDLQF--QYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFE 345 Query: 367 LMNQGKSV 374 + K+ Sbjct: 346 TASDPKTG 353 >2OUI-A nrPDB Length = 360 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 86/365 (23%), Positives = 141/365 (38%), Gaps = 39/365 (10%) Query: 24 IEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVT 83 E ++ + ++ +A + C +D + + G +I+GHEA G + +G V Sbjct: 14 WIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVK 73 Query: 84 NVKPGDKVI-PLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKP 142 +K GDKVI P P + + + G + G Sbjct: 74 RLKVGDKVIVPAITPDWGEEESQRGYPMHSGGML-----------------------GGW 110 Query: 143 VYHFFGTSTFSQYTVV--SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGST 200 + F FS+ V +D NLA + D E +L +TG+ A A + G T Sbjct: 111 KFSNFKDGVFSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDT 169 Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI 260 V G+G VGL +V G GA RI + A GATD +N ++ I E I Sbjct: 170 VCVIGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN--GDIVEQI 227 Query: 261 IELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG-- 317 ++ T G GVD + G T A+ G + + I E +G Sbjct: 228 LKATDGKGVDKVVIAGGDVHTFAQAVKMIKPGS-DIGNVNYLGEGDNIPIPRSEWGVGMG 286 Query: 318 -RTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP-FDKISEAFDLMNQGKS-- 373 + I+G G + + KL + K + L+TH +K+ +A LM + Sbjct: 287 HKHIHGGLTPGGRV--RMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKNKPADL 344 Query: 374 VRTIL 378 ++ ++ Sbjct: 345 IKPVV 349 >2H6E-A nrPDB Length = 344 Score = 231 bits (588), Expect = 4e-61, Method: Composition-based stats. Identities = 91/382 (23%), Positives = 155/382 (40%), Gaps = 48/382 (12%) Query: 7 VIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDS--KFEGLAFP 64 ++K KAA+ + +PL IE+V + P+ EV I+I +C TD V +G P Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 +I+GHE AG + +G + VK GD V+ C++C N+C Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTT- 118 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVV-SDINLAKIDDDANLERVCLLGCGFS 183 FS+Y +V S L K++ + +E L + Sbjct: 119 ------------------------NGGFSEYMLVKSSRWLVKLNSLSPVE-AAPLADAGT 153 Query: 184 TGYGA---AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAS-RIIGIDINSEKFVKAK 239 T GA A+ V G+GG+ + + KA + I+GI + + A Sbjct: 154 TSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFAL 213 Query: 240 ALGATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFI 298 LGA +D +I +LT G G A+D G ET L A G+ + Sbjct: 214 ELGADYVSEMKDAE----SLINKLTDGLGASIAIDLVGTEET-TYNLGKLLAQEGAIILV 268 Query: 299 GVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPF 358 G+ L F + + + + G+ +G ++ + +L K K + + +P Sbjct: 269 GMEGKRVSLEAF-DTAVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYIIK------VPL 321 Query: 359 DKISEAFDLMNQGK-SVRTILI 379 D I++AF +++G+ R ++ Sbjct: 322 DDINKAFTNLDEGRVDGRQVIT 343 >6DKH-A nrPDB Length = 346 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 73/349 (20%), Positives = 129/349 (36%), Gaps = 42/349 (12%) Query: 38 RIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPL 94 +QI +C +D G + P+++GHE G V I + + G V Sbjct: 34 LVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAIN 91 Query: 95 YAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQ 154 + C CK+C+ N C + G +Y F++ Sbjct: 92 PSKPCGHCKYCIEHNENQCTDMRFF--------------------GSAMYFPHVDGGFTR 131 Query: 155 YTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAV 214 Y +V A+ E+V + AA + A G + G+G +G V Sbjct: 132 YKMVETSQCVPYPAKAD-EKVMAFAEPLAVAIHAA-HQAGELQGKRVFISGVGPIGCLIV 189 Query: 215 MGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR--DLHKPIQEVIIELTKGGVDFAL 272 K GA+ I+ D++ K +GA +NP+ D+ E KG D + Sbjct: 190 SAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAE------KGYFDVSF 243 Query: 273 DCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVD 332 + +G ++ L+ T A G +G+ + FP +IG+ I + G ++ Sbjct: 244 EVSGHPSSVNTCLEVTRA-RGVMVQVGMGG---AMAEFPMMTLIGKEI--SLRGSFRFTS 297 Query: 333 SIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM-NQGKSVRTILIF 380 V+ N N L++ PF + EA ++ ++ + L+F Sbjct: 298 EFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF 346 >4UEJ-A nrPDB Length = 346 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 87/379 (22%), Positives = 157/379 (41%), Gaps = 44/379 (11%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKA-HEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGH 69 ++ + + + E + K EVR++I ++ LC +D I K +P+ +GH Sbjct: 1 MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIF-KNGAHYYPITLGH 59 Query: 70 EAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLM 129 E +G ++++G GV ++ PGD V + C C CL + C K + S Sbjct: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSR------- 112 Query: 130 EDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAA 189 F++Y VV N+ + D +E + + G A Sbjct: 113 ------------------RDGGFAEYIVVKRKNVFALPTDMPIEDGAFIE-PITVGLHA- 152 Query: 190 INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNP 249 + A+ + G G +GL A+ A GA + IDI+SEK AK+ GA N Sbjct: 153 FHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNS 212 Query: 250 RDLHKP-IQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 ++ P +Q V+ EL L+ AG +T++ A++ +G LT Sbjct: 213 SEMSAPQMQSVLRELRFN--QLILETAGVPQTVELAVEIAGP-HAQLALVGTLHQDLHLT 269 Query: 309 -------IFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKI 361 + E +IG +N + + ++ +L+T+ +K +L+ L+ H F+ Sbjct: 270 SATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTE---RKLSLEPLIAHRGSFESF 326 Query: 362 SEAF-DLMNQGKSVRTILI 379 ++A D+ + +LI Sbjct: 327 AQAVRDIARNAMPGKVLLI 345 >6FG0-A nrPDB Length = 352 Score = 226 bits (577), Expect = 1e-59, Method: Composition-based stats. Identities = 80/365 (21%), Positives = 140/365 (38%), Gaps = 35/365 (9%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVID--SKFEGLAFPVIVG 68 KA E G + ++ P E+ +++ A LCH+D TV+D + P+ +G Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 69 HEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQL 128 HE G V +G GVT GD V C C C N C + ++L Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPP---- 117 Query: 129 MEDKTSRFTCKGKPVYHFFGTSTFSQYTVVS-DINLAKIDDDANLERVCLLGCGFSTGYG 187 + + ++Y +V +L I D + L G + + Sbjct: 118 ----------------GYGSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHA 161 Query: 188 AAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL 247 + + PGST V G+GG+G + +A A+R+I +D++ ++ A+ +GA + Sbjct: 162 ISRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAV 221 Query: 248 NPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 + I ELT G G D G T+ A A G + +G+ AG+ Sbjct: 222 KSG---AGAADAIRELTGGQGATAVFDFVGAQSTIDTAQQVV-AVDGHISVVGIHAGAHA 277 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 F + W + + ++V + + ++ T T D+ A+ Sbjct: 278 KVGFWMIPFGASVV----TPYWGTRSELMEVVALARAGRLDIH---TETFTLDEGPAAYR 330 Query: 367 LMNQG 371 + +G Sbjct: 331 RLREG 335 >4GKV-A nrPDB Length = 336 Score = 220 bits (561), Expect = 6e-58, Method: Composition-based stats. Identities = 90/370 (24%), Positives = 153/370 (41%), Gaps = 40/370 (10%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHE 70 KAA+ + + + + K E +++ +CHTD V + F G VI+GHE Sbjct: 2 KAAVVTKDHH-VDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDF-GDKTGVILGHE 59 Query: 71 AAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLM 129 G+V +GPGVT++KPGD+ + + C C++C S LC + N Sbjct: 60 GIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSV------ 113 Query: 130 EDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAA 189 ++ +V K+ D + + C T Y A Sbjct: 114 -------------------DGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTY-KA 153 Query: 190 INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNP 249 + +K+ PG A++GLGG+G A+ K +++I ID+N E+ A +GA +N Sbjct: 154 VKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINS 213 Query: 250 RDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTI 309 + +++ E T GG A+ A +A+D AG G +G+ S L I Sbjct: 214 --HTEDAAKIVQEKT-GGAHAAVVTAVAKAAFNSAVDAVRAG-GRVVAVGLPPESMSLDI 269 Query: 310 FPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMN 369 P ++ G + G+ G + + + + K + V P I+ F M Sbjct: 270 -PRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGK-----VVPKVALR-PLADINTIFTEME 322 Query: 370 QGKSVRTILI 379 +GK ++I Sbjct: 323 EGKIRGRMVI 332 >3UOG-A nrPDB Length = 363 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 84/389 (21%), Positives = 149/389 (38%), Gaps = 47/389 (12%) Query: 1 MGTKGKVIKCKAAIAWE-------AGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATV 53 +GT+ + + + A L + E V H++ ++ +A SL + D V Sbjct: 13 LGTENLYFQSMMSKWMQEWSTETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLV 72 Query: 54 IDSKFE-GLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNL 112 +++ LAFP + + +G+VE++G VT +PGD+VI +AP Sbjct: 73 LETGMGLDLAFPFVPASDMSGVVEAVGKSVTRFRPGDRVISTFAPGW------------- 119 Query: 113 CGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANL 172 + +T + G S+Y V+ + + Sbjct: 120 ----------LDGLRPGTGRTPAYETLGGA-----HPGVLSEYVVLPEGWFVAAPKSLDA 164 Query: 173 ERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINS 232 L C T + A + + G V G GGV L + KA GA +I + Sbjct: 165 AEASTLPCAGLTAWFALVEKGHLRAGDRVVVQGTGGVALFGLQIAKATGA-EVIVTSSSR 223 Query: 233 EKFVKAKALGATDCLNPRDLHKPIQEVIIELT-KGGVDFALDCAGGSETMKAALDCTTAG 291 EK +A ALGA +N L + E + LT G D L+ AGG+ + +L Sbjct: 224 EKLDRAFALGADHGIN--RLEEDWVERVYALTGDRGADHILEIAGGAG-LGQSLKAVAP- 279 Query: 292 WGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDAL 351 G + IGV G + L+ + G G ++++ + V + L + Sbjct: 280 DGRISVIGVLEGFEVSGPVGPLLLKSPVVQGISVGHRRALEDLVGAVD-----RLGLKPV 334 Query: 352 VTHTLPFDKISEAFDLMNQGKSVRTILIF 380 + F ++ EA +++G + ++ F Sbjct: 335 IDMRYKFTEVPEALAHLDRGPFGKVVIEF 363 >5H82-A nrPDB Length = 389 Score = 218 bits (556), Expect = 3e-57, Method: Composition-based stats. Identities = 75/340 (22%), Positives = 130/340 (38%), Gaps = 20/340 (5%) Query: 33 KAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV- 91 H+V+ +++ LC D + + +P + GHE GIV IG V K GDKV Sbjct: 52 GEHDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVG 111 Query: 92 IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST 151 + + C KC+ C L C K+ A E+ T G +G Sbjct: 112 VGNFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSD---ENNTVYGDVSGDGEDRIYG--G 166 Query: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGL 211 +S V ++ + + ++ L + CG Y + PG + V G G +G Sbjct: 167 YSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGK 226 Query: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFA 271 AV KA GA+ + S+K + G L ++ + ++ + +D Sbjct: 227 LAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKEPEE------MKAAESTLDGI 280 Query: 272 LDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSV 331 DC + L+ G+ +GVA + L + P L+ R G+ G K Sbjct: 281 FDCVPSVHPLHPLLNLLKF-EGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMKET 338 Query: 332 DSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQG 371 + D+ K + + +P D ++ A + + +G Sbjct: 339 QEML----DFAAKHNIVSDI--ELIPMDYVNTALERIAKG 372 >3TWO-A nrPDB Length = 348 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 75/331 (22%), Positives = 126/331 (38%), Gaps = 35/331 (10%) Query: 8 IKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIV 67 ++ K + + + +V I I+ +CH+D S+++ +P+I Sbjct: 3 VQSKGFAIFSKDEHFKPHDFSRHAVGPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIP 62 Query: 68 GHEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 GHE AGI++ +G GV K GD V + + C+ CK C C K+ Sbjct: 63 GHEIAGIIKEVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKVVFT------- 115 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY 186 + C + +S VV + + +D +A LE+V L C T Y Sbjct: 116 ---------YDCLDSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTY 166 Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 + +KVT G+ V G GG+G AV A GA + N K A ++G Sbjct: 167 SP-LKFSKVTKGTKVGVAGFGGLGSMAVKYAVAMGA-EVSVFARNEHKKQDALSMGVKHF 224 Query: 247 -LNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA--G 303 +P+ + + DF + +K L T G +G+ Sbjct: 225 YTDPKQCKEEL------------DFIISTIPTHYDLKDYLKLLTY-NGDLALVGLPPVEV 271 Query: 304 SKGLTIFPEELIIGRTINGTFFGGWKSVDSI 334 + L++F + R + G+ GG K + Sbjct: 272 APVLSVFDFIHLGNRKVYGSLIGGIKETQEM 302 >3IP1-A nrPDB Length = 404 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 74/389 (19%), Positives = 138/389 (35%), Gaps = 52/389 (13%) Query: 15 AWEAGKPLCIEEVEVAP-PKAHEVRIQIIATSLCHTDATVIDSKFEG-------LAFPVI 66 W + + +EEV K E+ I++ A +C +D + + EG FPV Sbjct: 36 VWRYPE-VRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVT 94 Query: 67 VGHEAAGIVESIGPGV------TNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 +GHE +G+V GP + G+ V C C+ C N C ++ L Sbjct: 95 LGHEFSGVVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELG 154 Query: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLER------ 174 F++Y V + + + Sbjct: 155 FNV-------------------------DGAFAEYVKVDAKYAWSLRELEGVYEGDRLFL 189 Query: 175 VCLLGCGFSTGYGAA-INNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSE 233 L S Y A + + PG + G G +GL+AV K AGAS++I + + Sbjct: 190 AGSLVEPTSVAYNAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEV 249 Query: 234 KFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSE-TMKAALDCTTAG 291 + AK LGA ++P + E +++ T G G L+ G + + Sbjct: 250 RRNLAKELGADHVIDP--TKENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRA 307 Query: 292 WGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDAL 351 G + + A + E+ R G + P++++ + ++ + Sbjct: 308 RGINATVAIVARADAKIPLTGEVFQVRRAQIVGSQGHSGHGTFPRVISLMASG-MDMTKI 366 Query: 352 VTHTLPFDKISEAFDLMNQGKSVRTILIF 380 ++ T+ ++I E + KS+ + + Sbjct: 367 ISKTVSMEEIPEYIKRLQTDKSLVKVTML 395 >6C49-A nrPDB Length = 350 Score = 199 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 78/373 (20%), Positives = 150/373 (40%), Gaps = 43/373 (11%) Query: 9 KCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVG 68 +A A +AG+ L + + + H+V +++ LCH+D +V+++++ +PV+ G Sbjct: 13 TIQAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAG 72 Query: 69 HEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQ 127 HE G + ++G ++ G +V I A C+ C C+ LC Sbjct: 73 HEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCT------------- 119 Query: 128 LMEDKTSRFTCKGKPVYHFFGT-STFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY 186 G+ + G F+ + +D + E L CG T + Sbjct: 120 ------------GENIATIVGHAGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVF 167 Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 + + K+ V G+GG+G A+ KA G I N +K + KA+GA Sbjct: 168 DPLLKH-KIQATHHVGVIGIGGLGHIAIKLLKAWG-CEITAFSSNPDKTEELKAMGADHV 225 Query: 247 LNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 +N RD ++ KG D L + +A + T A GS F+G+ Sbjct: 226 VNSRDTEA------VKAQKGKFDLLLSTVNVTLNWRAFI-STLAPNGSLHFLGLTLEPVP 278 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 ++ + +++ G+ G ++ +L+ KK P +++EA + Sbjct: 279 VS-VGSLIDGAKSVTGSPTGSPAALR---QLLKFAARKKIAPQ---IELFPMSQLNEAIE 331 Query: 367 LMNQGKSVRTILI 379 ++ G++ I++ Sbjct: 332 RLHSGQARYRIVL 344 >1YQX-A nrPDB Length = 366 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 79/341 (23%), Positives = 126/341 (36%), Gaps = 37/341 (10%) Query: 33 KAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV- 91 +VR +++ +CH+D I + + +P++ GHE G V +G V V GDKV Sbjct: 40 GEEDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVG 99 Query: 92 IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST 151 + C C+ C + L N C K+ + G Y Sbjct: 100 VGCLVGACHSCESCANDLENYCPKM-------------ILTYASIYHDGTITY-----GG 141 Query: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGL 211 +S + V ++ + + D+ L+ L C T Y PG + GLGG+G Sbjct: 142 YSNHMVANERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGH 201 Query: 212 SAVMGCKAAGASRIIGIDINSEKFVKA-KALGATDCLNPRDLHKPIQEVIIELTKGGVDF 270 AV KA G S++ I + K +A K GA L RD + ++ G +D Sbjct: 202 VAVKFAKAFG-SKVTVISTSPSKKEEALKNFGADSFLVSRDQEQ------MQAAAGTLDG 254 Query: 271 ALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTIN-GTFFGGWK 329 +D + + G +G L F LI GR I G+ GG K Sbjct: 255 IIDTVSAVHPLLPLFGLLKS-HGKLILVGAPEKPLELPAF--SLIAGRKIVAGSGIGGMK 311 Query: 330 SVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQ 370 + + D V T D ++ A + + + Sbjct: 312 ETQEM---IDFAAKHNITADIEVIST---DYLNTAMERLAK 346 >5Z0C-A nrPDB Length = 374 Score = 195 bits (495), Expect = 3e-50, Method: Composition-based stats. Identities = 78/371 (21%), Positives = 129/371 (34%), Gaps = 35/371 (9%) Query: 2 GTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL 61 GT+ +K A + L +V +++ +CH+D I +++ Sbjct: 6 GTEEHTVKAVGWAARDPSGHLSPFTFSRRATGELDVTFKVLYCGICHSDLHYIKNEWSNT 65 Query: 62 AFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 +P + GHE G V +G V K GDKV + C C C + L N C Sbjct: 66 IYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGCIVGSCHSCPNCNNHLENYCPN----- 120 Query: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180 T + +S VV + +I D L+ L C Sbjct: 121 -------------RILTFGSRYYDGTLNHGGYSDLMVVQEHFAVRIPDALPLDSAAPLLC 167 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 T Y PG V GLGG+G AV KA G ++ + + K A + Sbjct: 168 AGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAKAFGV-KVTVVSTSPAKKEDAIS 226 Query: 241 -LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG 299 LGA + D + ++ G +D +D S + + + G +G Sbjct: 227 GLGAHSFILSTDAEQ------MQAAVGTMDGIIDTVSASHPLPPLISLLKS-HGKLVMVG 279 Query: 300 VAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFD 359 L +FP L+ + + G+ GG K + + + D V P D Sbjct: 280 DPPKPLELPVFP-LLLGRKMVAGSAIGGMKETQEM---IDFAAKEGVRADVEVI---PMD 332 Query: 360 KISEAFDLMNQ 370 ++ A +++ Sbjct: 333 YVNTAMQRVSK 343 >1WLY-A nrPDB Length = 333 Score = 193 bits (490), Expect = 1e-49, Method: Composition-based stats. Identities = 91/386 (23%), Positives = 136/386 (35%), Gaps = 72/386 (18%) Query: 10 CKAAIAWEAGKP--LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL---AFP 64 AA+ + G P EEV+V P +VR++ A + D L P Sbjct: 2 VMAAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPP 61 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 ++VG EAA +VE +GPGVT+ G++V P Sbjct: 62 IVVGFEAAAVVEEVGPGVTDFTVGERVCTCLPP--------------------------- 94 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCG--F 182 +SQ + L K+ D +L+ V L G Sbjct: 95 ------------------------LGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKG 130 Query: 183 STGYGAAINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 T KV PG + GG+G V + GA +IG EK A+ L Sbjct: 131 MTAQYLLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGA-TVIGTVSTEEKAETARKL 189 Query: 242 GATDCLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 G +N + EV+ E+T G GVD D G +T++ +LDC G C G Sbjct: 190 GCHHTINYST--QDFAEVVREITGGKGVDVVYDSIG-KDTLQKSLDCLRP-RGMCAAYGH 245 Query: 301 AAGSKGLTI------FPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTH 354 A+G L I R + +D K + D K L + V Sbjct: 246 ASGVADPIRVVEDLGVRGSLFITRPALWHYMSNRSEIDEGSKCLFD-AVKAGVLHSSVAK 304 Query: 355 TLPFDKISEAFDLMNQGKSVRTILIF 380 T P + + A M +++ +I++ Sbjct: 305 TFPLREAAAAHKYMGGRQTIGSIVLL 330 >5FI5-A nrPDB Length = 357 Score = 188 bits (477), Expect = 4e-48, Method: Composition-based stats. Identities = 69/373 (18%), Positives = 135/373 (36%), Gaps = 41/373 (10%) Query: 8 IKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIV 67 +K A ++ H+V+++++ C D + +KF ++P ++ Sbjct: 16 VKAFGLAAKDSSGLFSPFNFSRRATGEHDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVL 75 Query: 68 GHEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 GHE G V +G V K GDKV + C KC+ C + + N C + ++ S Sbjct: 76 GHEIVGEVTEVGSKVQKFKVGDKVGVASIIETCGKCEMCTNEVENYCPEAGSIDSNY--- 132 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY 186 S V+++ + + ++ L+ L C T Y Sbjct: 133 -----------------------GACSNIAVINENFVIRWPENLPLDSGVPLLCAGITAY 169 Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 PG + GLGG+G A+ KA GA + +K + GA Sbjct: 170 SPMKRYGLDKPGKRIGIAGLGGLGHVALRFAKAFGAKVTVISSSLKKKREAFEKFGADSF 229 Query: 247 LNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKG 306 L + + ++ G +D +D G+ +++ L G +G Sbjct: 230 LVSSNPEE------MQGAAGTLDGIIDTIPGNHSLEPLLALLKP-LGKLIILGAPEMPFE 282 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD 366 + P L+ G+ + + G K + + + ++ N+ A V + D ++ A + Sbjct: 283 VPA-PSLLMGGKVMAASTAGSMKEIQEMIEFAAEH-----NIVADV-EVISIDYVNTAME 335 Query: 367 LMNQGKSVRTILI 379 ++ +I Sbjct: 336 RLDNSDVRYRFVI 348 >5VKT-A nrPDB Length = 362 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 83/368 (22%), Positives = 132/368 (35%), Gaps = 40/368 (10%) Query: 10 CKAAIAW---EAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVI 66 CK A W +A L +V I+++ +CHTD VI +++ +PV+ Sbjct: 7 CKTAHGWAARDASGHLSPYSFSARIQGDADVTIKVLFCGICHTDLHVIKNEWGNAMYPVV 66 Query: 67 VGHEAAGIVESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 GHE G+V +G GVT K GD V + + CR C+ C + N C + Sbjct: 67 PGHEVVGVVTDVGHGVTKFKAGDTVGVGYFVDSCRTCESCSTGHENYCPDLV-------- 118 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGT--STFSQYTVVSDINLAKIDDDANLERVCLLGCGFS 183 T G +H T FS VVS + ++ + L+ L C Sbjct: 119 ----------LTSNGVDHHHHGATTKGGFSDVLVVSQDFVVRVPESLPLDGAAPLLCAGV 168 Query: 184 TGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK-ALG 242 T Y A PG V GLGG+G AV KA G + I + K +A LG Sbjct: 169 TVYSPMAQYALNEPGKHLGVVGLGGLGHMAVKFAKAFGM-TVTVISSSPGKRDEALGRLG 227 Query: 243 ATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAA 302 A L D + +D +D + L G +G + Sbjct: 228 ADAFLVSHDAAQMKAAAAT------LDGIIDTVSAGHQIVPLLALLKP-MGQMVVVGAPS 280 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 L + + G+ + G G ++ + + A + + D ++ Sbjct: 281 TPLELPAY-AIITGGKRVAGNGVGSVADCQAMLDFA-----GEHGVTADI-EVVQMDYVN 333 Query: 363 EAFDLMNQ 370 A + + + Sbjct: 334 TAIERLEK 341 >3WLE-A nrPDB Length = 341 Score = 183 bits (465), Expect = 8e-47, Method: Composition-based stats. Identities = 83/357 (23%), Positives = 138/357 (38%), Gaps = 49/357 (13%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNV 85 ++ V PKA ++ +++ A LCH+D VI ++GHE AG V ++G V N Sbjct: 28 DLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGL-DCGDNYVMGHEIAGTVAAVGDDVINY 86 Query: 86 KPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYH 145 K GD+V + C CK+C + N+C + Sbjct: 87 KVGDRVACVGPNGCGGCKYCRGAIDNVCKNAFG-----------------------DWFG 123 Query: 146 FFGTSTFSQYTVV-SDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF 204 + QY +V NL++I D+ + + T Y A I A+V+P S + Sbjct: 124 LGYDGGYQQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPYHA-IKMAQVSPTSNILLI 182 Query: 205 GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIE-L 263 G GG+G +A+ KA GA ++ +D E +AK LGA + E + E + Sbjct: 183 GAGGLGGNAIQVAKAFGA-KVTVLDKKKEARDQAKKLGAD----------AVYETLPESI 231 Query: 264 TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL-IIGRTING 322 + G D T + V G+ L+ +L + I G Sbjct: 232 SPGSFSACFDFVSVQATFDVCQKYVEPKG---VIMPVGLGAPNLSFNLGDLALREIRILG 288 Query: 323 TFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMN-QGKSVRTIL 378 +F+G +D + KLV++ K K A ++ E + + R + Sbjct: 289 SFWGTTNDLDDVLKLVSEGKVKPVVRSA------KLKELPEYIEKLRNNAYEGRVVF 339 >4OAQ-A nrPDB Length = 367 Score = 180 bits (456), Expect = 1e-45, Method: Composition-based stats. Identities = 70/361 (19%), Positives = 133/361 (36%), Gaps = 34/361 (9%) Query: 16 WEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL-AFPVIVGHEAAGI 74 W K E ++ H+V ++ LC++D + + ++ L ++VGHE G Sbjct: 20 WNRPKLASYERKQIN---PHDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGE 76 Query: 75 VESIGPGVTNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKT 133 V ++G VT K GD+V I + CR C+ C S C + Sbjct: 77 VIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQ----------------GA 120 Query: 134 SRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNA 193 + + K ++ +S +++ + + I +D L C T + I N Sbjct: 121 ATYNSKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNL 180 Query: 194 KVTP-GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL 252 + G + G+GG+G A+ A GA+ + +S K +A LGA D + + Sbjct: 181 GLDARGKNVGIIGIGGLGHLALQFANAMGAN-VTAFSRSSSKKEQAMKLGAHDFVATGED 239 Query: 253 HKPIQEVIIELTKGGVDFALDCAGGSETMKAA-LDCTTAGWGSCTFIGVAAGSKGLTIFP 311 + DF L+CA G + + + T +G+ + P Sbjct: 240 KTWYKNY-----DDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSP 294 Query: 312 EELI-IGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQ 370 + G + + G V + L + + + ++ + ++A D + Sbjct: 295 FTFLQQGASFGSSLLGSKTEVKEMLNLAAKHNVRPMIEEVPISE----ENCAKALDRCHA 350 Query: 371 G 371 G Sbjct: 351 G 351 >2DPH-A nrPDB Length = 398 Score = 176 bits (447), Expect = 1e-44, Method: Composition-based stats. Identities = 79/411 (19%), Positives = 149/411 (36%), Gaps = 69/411 (16%) Query: 12 AAIAWEAGKPLCIEEVEVAPPK------AHEVRIQIIATSLCHTDATVIDSKFEGLAFPV 65 ++ + + L +E V + H V +++++T++C +D + +F Sbjct: 4 KSVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPK-GH 62 Query: 66 IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASD 125 ++GHE G V G V + GD V + C +C+ C +++C +NL +P +D Sbjct: 63 VLGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCE--NNLVNPDAD 120 Query: 126 QQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVS--DINLAKI-DDDANLERV---CLLG 179 ++ ++Y +V D L K D + +E++ L+ Sbjct: 121 LGAFGFDLKGWS------------GGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLIS 168 Query: 180 CGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 239 TG+ + +A V PGS + G G VG A G + GA+ +I D N E+ Sbjct: 169 DILPTGFHGCV-SAGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLS 227 Query: 240 ALGAT--DCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSE--------------TMKA 283 G D N L I ++ L K VD +D G + + Sbjct: 228 DAGFETIDLRNSAPLRDQIDQI---LGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNS 284 Query: 284 ALDCTTAGWGSCTFIGVAAGSKGLTI------------FPEELIIGRTINGTFFGGWKSV 331 D AG G+ G+ GS + F + I Sbjct: 285 LFDVVRAG-GAIGIPGIYVGSDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYN 343 Query: 332 DSIPKLVTD----YKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTIL 378 + + + Y +K N++ + D+ + + ++G + ++ Sbjct: 344 RHLTEAILWDQMPYLSKVMNIE-----VITLDQAPDGYAKFDKGSPAKFVI 389 >4JLW-A nrPDB Length = 399 Score = 174 bits (441), Expect = 6e-44, Method: Composition-based stats. Identities = 79/403 (19%), Positives = 147/403 (36%), Gaps = 57/403 (14%) Query: 14 IAWEAGKPLCIEEVEVAP---PKA----HEVRIQIIATSLCHTDATVIDSKFEGLAFPVI 66 + + + ++ + P+ H V +++++T++C +D ++ + ++ Sbjct: 7 VVYLGPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPE-GLV 65 Query: 67 VGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 +GHE G V IG GV +K GD V + C C+ C T +C ++ ++ + Sbjct: 66 LGHEITGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPARAGGAYG 125 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVS--DINLAKID-DDANLERVCLLGC--- 180 + ++Y +V D NL K+ +A +E++ L C Sbjct: 126 YVDMGG---------------WVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSD 170 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 TGY A+ A V PGST + G G VGL+A + GA+ +I D+N + AK Sbjct: 171 ILPTGYHGAV-TAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKK 229 Query: 241 LGATDCLNPRDLHKPIQEVIIELTK-GGVDFALDCAG--------------GSETMKAAL 285 G +D P+ E I L VD A+D G T+ +L Sbjct: 230 QGFEIADLSKDT--PLHEQIAALLGEPEVDCAVDAVGFEARGHGHSGSQQEAPATVLNSL 287 Query: 286 DCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTF---------FGGWKSVDSIPK 336 T G G+ + +I G + + Sbjct: 288 MGITRVAGKIGIPGLYVTEDPGAVDAAAKHGALSIRFGLGWAKSHSFHTGQTPVMKYNRQ 347 Query: 337 LVTDYKNKKFNLDALV-THTLPFDKISEAFDLMNQGKSVRTIL 378 L+ + + +V + D + + + G + ++ Sbjct: 348 LMQAIMWDRIKIADIVGVEVITLDDAPKGYGEFDAGVPKKFVI 390 >5H83-A nrPDB Length = 360 Score = 173 bits (439), Expect = 9e-44, Method: Composition-based stats. Identities = 69/339 (20%), Positives = 122/339 (35%), Gaps = 37/339 (10%) Query: 33 KAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKV- 91 ++V+ +++ C+ D + +KF +P ++GHE G+V IG V K GDKV Sbjct: 38 GENDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVG 97 Query: 92 IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST 151 + + C KC+ C++ + N C K+ + + Sbjct: 98 VGGFVGACEKCEMCVNGVENNCSKVESTDGHFGNNF----------------------GG 135 Query: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGL 211 VV++ ++ L L C T Y PG + GLGG+G Sbjct: 136 CCNIMVVNEKYAVVWPENLPLHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIAGLGGLGH 195 Query: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFA 271 A+ KA GA + +K + G L + + ++ G +D Sbjct: 196 LAIRFAKAFGAKVTLISSSVKKKREALEKFGVDSFLLNSNPEE------MQGAYGTLDGI 249 Query: 272 LDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSV 331 +D + ++ L G +GV + P L+ G+ I G+ G K Sbjct: 250 IDTMPVAHSIVPFLALLKP-LGKLIILGVPEEPFEVPA-PALLMGGKLIAGSAAGSMKET 307 Query: 332 DSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQ 370 + K N+ A V +P D ++ A + + Sbjct: 308 QEMIDFAA-----KHNIVADV-EVIPIDYLNTAMERIKN 340 >1KOL-A nrPDB Length = 398 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 84/403 (20%), Positives = 153/403 (37%), Gaps = 57/403 (14%) Query: 14 IAWEAGKPLCIEEVEVAPPK-------AHEVRIQIIATSLCHTDATVIDSKFEGLAFPVI 66 + + + +++++ + H V +++++T++C +D ++ + ++ Sbjct: 6 VVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGR-TTAQVGLV 64 Query: 67 VGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 +GHE G V G V N++ GD V + C +C+ C T +C ++ ++ + Sbjct: 65 LGHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPARAGGAYG 124 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVS--DINLAKIDD-DANLERVCLLGC--- 180 + T ++Y +V D NL K+ D D +E++ L C Sbjct: 125 YVDMGD---------------WTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSD 169 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 TGY A+ A V PGST V G G VGL+A + GA+ +I D+N + AKA Sbjct: 170 ILPTGYHGAV-TAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKA 228 Query: 241 LGATDCLNPRDLHKPIQEVIIELTK-GGVDFALDCAG--------------GSETMKAAL 285 G + L P+ E I L VD A+D G T+ +L Sbjct: 229 QGFE--IADLSLDTPLHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSL 286 Query: 286 DCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTIN--------GTFFGGWKSVDSIPK- 336 T G G+ + I +I +F G V + Sbjct: 287 MQVTRVAGKIGIPGLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRA 346 Query: 337 LVTDYKNKKFNLDALV-THTLPFDKISEAFDLMNQGKSVRTIL 378 L+ + N+ +V + D + + G + ++ Sbjct: 347 LMQAIMWDRINIAEVVGVQVISLDDAPRGYGEFDAGVPKKFVI 389 >1Q1N-A nrPDB Length = 360 Score = 171 bits (433), Expect = 4e-43, Method: Composition-based stats. Identities = 76/361 (21%), Positives = 132/361 (36%), Gaps = 40/361 (11%) Query: 16 WEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIV 75 W+ K + H++ I+I A +C +D + + P++VGHE G V Sbjct: 18 WKNPKKTKYDPKPF---YDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKV 74 Query: 76 ESIGPGV-TNVKPGDKV-IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKT 133 +GP + +K G +V + C +C C + C K S + Sbjct: 75 VKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDG------ 128 Query: 134 SRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNA 193 + ++ Y V + + I ++ L CG T Y + N Sbjct: 129 ------------YVSQGGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRN- 175 Query: 194 KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLH 253 PG + GLGG+G + KA GA + I +S K A +GA + + Sbjct: 176 GCGPGKKVGIVGLGGIGSMGTLISKAMGAETYV-ISRSSRKREDAMKMGADHYIATLE-E 233 Query: 254 KPIQEVIIELTKGGVDFALDCAGGSETMKAAL-DCTTAGWGSCTFIGVAAGSKGLTIFPE 312 E + D + CA + + G I + + L++ P Sbjct: 234 GDWGEKYFDT----FDLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPY 289 Query: 313 ELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK--ISEAFDLMNQ 370 L +I+ + G K ++ + KLV++ K + TLP + + EAF+ M + Sbjct: 290 GL-KAVSISYSALGSIKELNQLLKLVSEKDIK------IWVETLPVGEAGVHEAFERMEK 342 Query: 371 G 371 G Sbjct: 343 G 343 >3JYN-A nrPDB Length = 325 Score = 168 bits (425), Expect = 4e-42, Method: Composition-based stats. Identities = 80/371 (21%), Positives = 133/371 (35%), Gaps = 67/371 (18%) Query: 19 GKPLCIE--EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVE 76 G P +E + E P V ++ A L D + P +G E AG+VE Sbjct: 11 GGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVVE 70 Query: 77 SIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRF 136 ++G VT K GD+V Sbjct: 71 AVGDEVTRFKVGDRVA-------------------------------------------- 86 Query: 137 TCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVT 196 Y +S+ V+ + NL K+ D + E+ L T +V Sbjct: 87 -------YGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQYLLRQTYQVK 139 Query: 197 PGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKP 255 PG GGVG A KA GA ++IG + EK AKALGA + ++ H+ Sbjct: 140 PGEIILFHAAAGGVGSLACQWAKALGA-KLIGTVSSPEKAAHAKALGAWETIDYS--HED 196 Query: 256 IQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK-----GLTIF 310 + + ++ELT G + G +T +LD G G A+G G+ Sbjct: 197 VAKRVLELTDGKKCPVVYDGVGQDTWLTSLDSVAP-RGLVVSFGNASGPVSGVNLGILAQ 255 Query: 311 PEELIIGRTINGTFFGGWKSVDSI-PKLVTDYKNKKFNLDALVTHTLPFDKISEA-FDLM 368 + + + R G++ +++ ++ +L + K +D + ++A +L Sbjct: 256 KDSVYVTRPTLGSYANNAQNLQTMADELFDMLASGKLKVDGI--EQYALKDAAKAQIELS 313 Query: 369 NQGKSVRTILI 379 + + TILI Sbjct: 314 ARRTTGSTILI 324 >2VCY-A nrPDB Length = 344 Score = 165 bits (417), Expect = 3e-41, Method: Composition-based stats. Identities = 75/387 (19%), Positives = 135/387 (34%), Gaps = 70/387 (18%) Query: 9 KCKAAIAWEAGKPLCIEEV---EVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA-FP 64 + +A + G P + E+ E+A + +VR++++A + +D +I + L P Sbjct: 13 RVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELP 72 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 + G+E V ++G VT +KPGD VIP A Sbjct: 73 AVGGNEGVAQVVAVGSNVTGLKPGDWVIPANA---------------------------- 104 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFST 184 G T+ V S+ L ++ D L+ LG T Sbjct: 105 -----------------------GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCT 141 Query: 185 GYGAAINNAKVTPGSTCA-VFGLGGVGLSAVMGCKAAGASRIIGIDINSE--KF-VKAKA 240 Y ++ ++ PG + GVG + + A G I + + K + K+ Sbjct: 142 AYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKS 201 Query: 241 LGATDCLNPRDLHKP-IQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG 299 LGA + +L +P ++ ++ + AL+C GG + + L G T+ G Sbjct: 202 LGAEHVITEEELRRPEMKNFFKDMPQP--RLALNCVGGKSSTEL-LRQLARGGTMVTYGG 258 Query: 300 VAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKN-----KKFNLDALVTH 354 +A + + + G + WK S + ++ L A Sbjct: 259 MA-KQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACS 317 Query: 355 TLPFDKISEAFDL-MNQGKSVRTILIF 380 +P A + M S + IL Sbjct: 318 QVPLQDYQSALEASMKPFISSKQILTM 344 >1QOR-A nrPDB Length = 327 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 71/376 (18%), Positives = 127/376 (33%), Gaps = 66/376 (17%) Query: 15 AWEAGKPLCIEEVEVAP--PKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAA 72 + G P ++ VE P P +E++++ A + D + + + P +G EAA Sbjct: 7 FHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAA 66 Query: 73 GIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDK 132 GIV +G GV ++K GD+V+ Sbjct: 67 GIVSKVGSGVKHIKAGDRVV---------------------------------------- 86 Query: 133 TSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINN 192 Y +S + A + + E+ T Y Sbjct: 87 -----------YAQSALGAYSSVHNIIADKAAILPAAISFEQAAASFLKGLTVYYLLRKT 135 Query: 193 AKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRD 251 ++ P GGVGL A KA GA ++IG ++K A GA +N R+ Sbjct: 136 YEIKPDEQFLFHAAAGGVGLIACQWAKALGA-KLIGTVGTAQKAQSALKAGAWQVINYRE 194 Query: 252 LHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSK----- 305 + + E + E+T G V D G +T + +LDC G G ++G+ Sbjct: 195 --EDLVERLKEITGGKKVRVVYDSVGR-DTWERSLDCLQR-RGLMVSFGNSSGAVTGVNL 250 Query: 306 GLTIFPEELIIGRTINGTFFGGWKSVDSIP-KLVTDYKNKKFNLDALVTHTLPFDKISEA 364 G+ L + R + + + +L + + +D P A Sbjct: 251 GILNQKGSLYVTRPSLQGYITTREELTEASNELFSLIASGVIKVDVAEQQKYPLKDAQRA 310 Query: 365 FDLMNQGKSVRTILIF 380 +++ + + L+ Sbjct: 311 HEILESRATQGSSLLI 326 >1YB5-A nrPDB Length = 351 Score = 144 bits (363), Expect = 7e-35, Method: Composition-based stats. Identities = 70/396 (17%), Positives = 142/396 (35%), Gaps = 73/396 (18%) Query: 1 MGTKGKVIKC--------KAAIAWEAGKPLCIE---EVEVAPPKAHEVRIQIIATSLCHT 49 +GT+ + +A +E G P ++ ++ V PK H+V I++ A + Sbjct: 13 LGTENLYFQSMATGQKLMRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPV 72 Query: 50 DATVIDSKFEGLAF-PVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSP 108 + + + P G + AG++E++G Sbjct: 73 ETYIRSGTYSRKPLLPYTPGSDVAGVIEAVG----------------------------- 103 Query: 109 LTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDD 168 D S F + + +++Y + +D + K+ + Sbjct: 104 ----------------------DNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPE 141 Query: 169 DANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIG 227 + ++ +G + T Y A I++A V G + V G GGVGL+A +A G +I+G Sbjct: 142 KLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILG 200 Query: 228 IDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDC 287 E GA + N R+++ I ++ + + G+D ++ + L Sbjct: 201 TAGTEEGQKIVLQNGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANV-NLSKDLSL 258 Query: 288 TTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTING-TFFGGWKSVDSIPKLVTDYKNKKF 346 + G G +G + + + +I G T F K + Sbjct: 259 LSHG-GRVIVVG--SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIG 315 Query: 347 NLDALVTHTLPFDKISEAFDLM--NQGKSVRTILIF 380 L ++ P +K++EA + + G + + IL+ Sbjct: 316 WLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 351 >4J6F-A nrPDB Length = 382 Score = 141 bits (356), Expect = 4e-34, Method: Composition-based stats. Identities = 72/413 (17%), Positives = 126/413 (30%), Gaps = 79/413 (19%) Query: 1 MGTKGKVIKCK------------AAIAWEAGKPLCI---EEVEVAPPKAHEVRIQIIATS 45 +GT+ + A + G + +V V P A EV I++ A Sbjct: 13 LGTENLYFQSMMRMMHSVPKTMTAVLLTGHGGLEKLVYSRDVPVPAPAAGEVLIKVTACG 72 Query: 46 LCHTDATVIDSKFEG----------------LAFPVIVGHEAAGIVESIGPGVTNVKPGD 89 + +TD V + + L FP I G + G + ++G GV + G+ Sbjct: 73 MNNTDVWVREGAYGTEDDPSAVSTWRRHGNTLTFPRIQGTDTVGHIVAVGEGVDRARIGE 132 Query: 90 KVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGT 149 +V+ ++ + Sbjct: 133 RVMVDFSIY---------------------------------NRDDDSLADIDYMGHGRD 159 Query: 150 STFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGL-GG 208 +++Y + N + D + C + TG + A++ G T V G GG Sbjct: 160 GGYAEYMALPAENAHVVATDLTDIELATFCCAYLTG-ERMLERARLAAGETVLVTGASGG 218 Query: 209 VGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGG- 267 VG + + +A GA I K +GA + + E + + G Sbjct: 219 VGSAIIQLARARGAVPIAVAG--PGKEAAMLDIGAQAVV--TRGQGDLAEAVEAASGGRP 274 Query: 268 VDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGG 327 +D D GG L G T G AG + ++G+ G Sbjct: 275 IDVVADLVGGPL-FNDLLKILRP-EGRYTTAGAIAGPVVQLDLRTMYLKQLELHGSSQGS 332 Query: 328 WKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEA-FDLMNQGKSVRTILI 379 +LV + KK LV P + A D M + + +++ Sbjct: 333 RADFR---RLVRYIEEKKIR--PLVGGVYPLSEFHRAQTDFMAKNFVGKLVVV 380 >3HZZ-A nrPDB Length = 467 Score = 141 bits (355), Expect = 6e-34, Method: Composition-based stats. Identities = 75/398 (18%), Positives = 139/398 (34%), Gaps = 78/398 (19%) Query: 20 KPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA----------------- 62 K + ++EV V E + ++A+S+ + +V S FE ++ Sbjct: 74 KSIHLDEVPVPELGPGEALVAVMASSVNYN--SVWTSIFEPVSTFAFLERYGKLSPLTKR 131 Query: 63 --FPV-IVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNL 119 P I+G + AG+V GPGV +PGD+V+ C + Sbjct: 132 HDLPYHIIGSDLAGVVLRTGPGVNAWQPGDEVVA------------------HCLSVELE 173 Query: 120 KSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLG 179 D +++ + + ++ +V L E G Sbjct: 174 SPDGHDDTMLDPEQ-------RIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPG 226 Query: 180 CGFSTGYGAAI--NNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFV 236 ST Y + N A + G ++G GG+G A A GA+ I + + +K Sbjct: 227 LVNSTAYRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFALAGGANP-ICVVSSPQKAE 285 Query: 237 KAKALGATDCLN----------PRDLHKPIQ-----EVIIELTKGG-VDFALDCAGGSET 280 +++GA ++ P + + I ELT G +D + G ET Sbjct: 286 ICRSMGAEAIIDRNAEGYKFWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPGR-ET 344 Query: 281 MKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTD 340 A++ T G G+ T +G + + I G+ F ++ +L+ Sbjct: 345 FGASVYVTRKG-GTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAYEANRLIA- 402 Query: 341 YKNKKFNLDALVTHTLPFDKISEA----FDLMNQGKSV 374 K + ++ T ++ +A ++QGK Sbjct: 403 ----KGKIHPTLSKTYSLEETGQAAYDVHRNLHQGKVG 436 >2CF5-A nrPDB Length = 357 Score = 141 bits (354), Expect = 7e-34, Method: Composition-based stats. Identities = 80/370 (21%), Positives = 130/370 (35%), Gaps = 36/370 (9%) Query: 5 GKVIKCKAAIAWEAGKP---LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL 61 G + + W A P L + +V I+II +CHTD + Sbjct: 2 GIMEAERKTTGWAARDPSGILSPYTYTLRETGPEDVNIRIICCGICHTDLHQTKNDLGMS 61 Query: 62 AFPVIVGHEAAGIVESIGPGVTNVKPGD-KVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120 +P++ GHE G V +G V+ GD + C C C L C K Sbjct: 62 NYPMVPGHEVVGEVVEVGSDVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPK----- 116 Query: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180 + G+P F++ TVV + KI + +E+ L C Sbjct: 117 --------KIWSYNDVYINGQPT-----QGGFAKATVVHQKFVVKIPEGMAVEQAAPLLC 163 Query: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 T Y + PG + GLGGVG V KA G + N ++ + Sbjct: 164 AGVTVYSPLSHFGLKQPGLRGGILGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQD 223 Query: 241 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 LGA D + D K + EL +D+ +D ++ L G +GV Sbjct: 224 LGADDYVIGSDQAK-----MSELADS-LDYVIDTVPVHHALEPYLSLLKL-DGKLILMGV 276 Query: 301 AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 360 P ++ + I G+F G K + + + K K + + + D Sbjct: 277 INNPLQFLT-PLLMLGRKVITGSFIGSMKETEEM---LEFCKEKGLS---SIIEVVKMDY 329 Query: 361 ISEAFDLMNQ 370 ++ AF+ + + Sbjct: 330 VNTAFERLEK 339 >4DVJ-A nrPDB Length = 363 Score = 137 bits (346), Expect = 6e-33, Method: Composition-based stats. Identities = 73/402 (18%), Positives = 137/402 (34%), Gaps = 81/402 (20%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIE------EVEVAPPKAHEVRIQIIATSLCHTDATVI 54 +GT+ + A+ + P+ + E+ P H++ +++ A S+ D V Sbjct: 13 LGTENLYFQSMKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVR 72 Query: 55 DSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCG 114 S ++G++AAGIV ++GP VT +PGD+V Sbjct: 73 RSTPPDGTDWKVIGYDAAGIVSAVGPDVTLFRPGDEVF---------------------- 110 Query: 115 KISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLER 174 T +++ +V + + + + Sbjct: 111 ---------------------------YAGSIIRPGTNAEFHLVDERIVGRKPKTLDWAE 143 Query: 175 VCLLGCGFSTGYGAAINNAKVT---PGSTCAVF---GLGGVGLSAVMGCKAAGASRIIGI 228 L T + A + V PG+ A+ G GGVG AV + +I Sbjct: 144 AAALPLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTVIAT 203 Query: 229 DINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCT 288 E K+LGA + D KP+ + L G F ++ A + Sbjct: 204 ASRPETQEWVKSLGAHHVI---DHSKPLAAEVAALGLGAPAFVFSTT-HTDKHAAEIADL 259 Query: 289 TAGWGSCTFIGVAAGSKGLTIFPE------ELIIGRTINGT--FFGGWKSVDSIPKLVTD 340 A G I + + + EL+ R + GT + ++ + +LV + Sbjct: 260 IAPQGRFCLIDDPSAFDIMLFKRKAVSIHHELMFTRPMFGTPDMSEQGRLLNDVSRLVDE 319 Query: 341 YKNKKFNLDALVTHTL-PFDKIS--EAFDLMNQGKSVRTILI 379 + L +T+ L P + + +A L+ G + ++I Sbjct: 320 GR-----LRTTLTNRLSPINAANLKQAHALVESGTARGKVVI 356 >4RVS-A nrPDB Length = 329 Score = 133 bits (335), Expect = 1e-31, Method: Composition-based stats. Identities = 73/377 (19%), Positives = 113/377 (29%), Gaps = 60/377 (15%) Query: 12 AAIAWEAGKPLCIEEV--EVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGH 69 A E G P + V P E+ I+ A + D ++ P ++G Sbjct: 4 AIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYP-RELPFVIGS 62 Query: 70 EAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLM 129 E G VE++GPGVT D I + Sbjct: 63 EVCGTVEAVGPGVT---AADTAISV----------------------------------- 84 Query: 130 EDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAA 189 G V ++++ AK+ DD E T + Sbjct: 85 ----------GDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLL 134 Query: 190 INNAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + V G T V G GGVGL G R+I +EK +K GA L+ Sbjct: 135 KSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGV-RVITTVSTAEKAKLSKDAGADVVLD 193 Query: 249 PRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 + + ELT G GV D G + T A+L A G+ G A+G Sbjct: 194 YPEDAWQFAGRVRELTGGTGVQAVYDGVGAT-TFDASLASL-AVRGTLALFGAASGPVPP 251 Query: 308 TIFPEELIIGRTI--NGTFFGGWKSVDSIPKLVTDY--KNKKFNLDALVTHTLPFDKISE 363 G + F ++ + + + V P Sbjct: 252 VDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGNEAITVAVGGRYPLADALR 311 Query: 364 AFDLMNQGKSVRTILIF 380 A + K+V ++++ Sbjct: 312 AHQDLEARKTVGSVVLL 328 >2OBY-A nrPDB Length = 338 Score = 129 bits (323), Expect = 3e-30, Method: Composition-based stats. Identities = 70/373 (18%), Positives = 123/373 (32%), Gaps = 68/373 (18%) Query: 19 GKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKF-EGLAFPVIVGHEAAGIVES 77 + L ++EV P EV +++ A++L D ++ I+G EA+G V Sbjct: 18 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAE 77 Query: 78 IGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFT 137 +GPG C Sbjct: 78 LGPG-----------------------CQGHWK--------------------------- 87 Query: 138 CKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTP 197 G +QY V + L I + L + + + T + V Sbjct: 88 -IGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQA 146 Query: 198 GSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 G + GL GVG +A+ + AGA ++ + +K A+ LGA N + + Sbjct: 147 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLV-TAGSQKKLQMAEKLGAAAGFNYK--KEDF 203 Query: 257 QEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIG-VAAGSKGLTIFPEEL 314 E ++ TKG GV+ LDC GG + ++C A G G + G +F + L Sbjct: 204 SEATLKFTKGAGVNLILDCIGG-SYWEKNVNCL-ALDGRWVLYGLMGGGDINGPLFSKLL 261 Query: 315 IIGRTINGTFFGGWKSVDSIPKLVTDYKN--------KKFNLDALVTHTLPFDKISEAFD 366 ++ + + + + L ++ P +I EA Sbjct: 262 FKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHK 321 Query: 367 LMNQGKSVRTILI 379 M K++ I++ Sbjct: 322 YMEANKNIGKIVL 334 >4Y1B-A nrPDB Length = 425 Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats. Identities = 71/411 (17%), Positives = 137/411 (33%), Gaps = 71/411 (17%) Query: 1 MGTKGKVIKCKAAIAWEAGKP---LCIEEVEVAPPKAHEVRIQIIATSLCHT-------- 49 +GT K + G+P E V+V P +V ++++A + + Sbjct: 34 LGTAPKQMYASLIRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGE 93 Query: 50 --DATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLS 107 D K I G + +GIV ++G GV +KPG +V+ L C+ Sbjct: 94 PLDVIAARQKQGATEDFHIGGSDLSGIVWAVGDGVR-LKPGAEVVVL------ACR---- 142 Query: 108 PLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKID 167 A D +L D + T + +G +F+Q+ VV + Sbjct: 143 -----------WDESAQDIRLGADPVTSSTQRVWGYEENYG--SFAQFAVVDEYMCHPKP 189 Query: 168 DDANLERVCLLGCGFSTGYGA--AINNAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASR 224 + +T Y V PG ++ G GG+G A+ + G Sbjct: 190 QRLSWAAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGIP 249 Query: 225 IIGIDINSEKFVKAKALGATDCLNPRDLHKP-------IQEVIIELTKG----------- 266 + + + E+ LGA ++ R+ +E + + G Sbjct: 250 V-AVVSSEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEV 308 Query: 267 -----GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTIN 321 L+ +G ++T+ ++ G G G G + + + Sbjct: 309 LGERRAPRIVLEHSG-ADTIPTSIYM-ADNAGMVVICGGTTGYNGDVDLRFLWMRQKRLQ 366 Query: 322 GTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGK 372 G+ + I +L+ +D ++ T F++I A L++ + Sbjct: 367 GSHAASAREAREITRLIDQGA-----IDPCLSRTFGFEEIGLAHQLIHDNQ 412 >2VN8-A nrPDB Length = 375 Score = 123 bits (308), Expect = 2e-28, Method: Composition-based stats. Identities = 84/425 (19%), Positives = 140/425 (32%), Gaps = 112/425 (26%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCI---EEVEVAPPK-AHEVRIQIIATSLCHTDATVIDS 56 +GT+ + A + + GK + + + + +EV +++ A S+ D + Sbjct: 13 LGTENLYFQSMAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSG 72 Query: 57 ---------------KFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRK 101 K +G FP+ +G + +G+V G V KPGD+V P Sbjct: 73 YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPW--- 129 Query: 102 CKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDI 161 T S++ VVS Sbjct: 130 ----------------------------------------------KQGTLSEFVVVSGN 143 Query: 162 NLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVT----PGSTCAVFGL-GGVGLSAVMG 216 ++ + L T + A + G + G GGVG A+ Sbjct: 144 EVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQV 203 Query: 217 CKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAG 276 KA A + + + + + LGA D ++ + ++E + L DF LD G Sbjct: 204 MKAWDA-HVTAV-CSQDASELVRKLGADDVIDYKSGS--VEEQLKSLKP--FDFILDNVG 257 Query: 277 GSETMKAALDCTTAGWGS--CTFI-------------------GVAAGSKGLTIFPEELI 315 G T A D G+ T + GV GSK L F Sbjct: 258 G-STETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHF----W 312 Query: 316 IGRTINGTFF-GGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKS- 373 G FF +D I +LV K + ++ T PF K+ EAF + +G + Sbjct: 313 KGVHYRWAFFMASGPCLDDIAELVDAGKIR-----PVIEQTFPFSKVPEAFLKVERGHAR 367 Query: 374 VRTIL 378 +T++ Sbjct: 368 GKTVI 372 >4A10-A nrPDB Length = 447 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 60/382 (15%), Positives = 117/382 (30%), Gaps = 70/382 (18%) Query: 20 KPLCIEEVEVAPPKAHEVRIQIIATSLCHTDA----------------TVIDSKFEG--L 61 K L + EV + EV + ++A+S+ + + Sbjct: 48 KSLRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNARQGGWATRHD 107 Query: 62 AFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKS 121 ++G + +G+V G GV KPGD VI A + + Sbjct: 108 QPYHVLGSDCSGVVVRTGIGVRRWKPGDHVIVHPAHV----------------DEQEPAT 151 Query: 122 PASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCG 181 E + F ++Y VV L E + Sbjct: 152 HGDGMLGTEQRAWGFETN---------FGGLAEYGVVRASQLLPKPAHLTWEEAAVSPLC 202 Query: 182 FSTGYGAAI--NNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKA 238 T Y + A++ G ++G GG+G A+ K G + + +++K Sbjct: 203 AGTAYRMLVSDRGAQMKQGDIVLIWGASGGLGSYAIQFVKNGGGIPV-AVVSSAQKEAAV 261 Query: 239 KALGATDCLNPRDL-------HKP---------IQEVIIELTKGGVDFALDCAGGSETMK 282 +ALG +N +L P + ++++E D + G T Sbjct: 262 RALGCDLVINRAELGITDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGRV-TFG 320 Query: 283 AALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYK 342 ++ G G+ G ++G + + I G+ + + +L Sbjct: 321 LSVIVARRG-GTVVTCGSSSGYLHTFDNRYLWMKLKKIVGSHGANHEEQQATNRLFESGA 379 Query: 343 NKKFNLDALVTHTLPFDKISEA 364 + ++ P + +EA Sbjct: 380 -----VVPAMSAVYPLAEAAEA 396 >3TQH-A nrPDB Length = 321 Score = 122 bits (306), Expect = 2e-28, Method: Composition-based stats. Identities = 67/385 (17%), Positives = 129/385 (33%), Gaps = 75/385 (19%) Query: 4 KGKVIKCKAAIAWEAGKP--LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDS----- 56 + + KA + G P L + + + +++ I++ A SL D + Sbjct: 1 SNAMKEMKAIQFDQFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVA 60 Query: 57 KFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKI 116 K P +G++ +G V +G V NV GDKV+ + C C Sbjct: 61 KKLKNNLPSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--C----------- 107 Query: 117 SNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVC 176 +++Y S + + + + + Sbjct: 108 -----------------------------------YAEYVCASPDTIIQKLEKLSFLQAA 132 Query: 177 LLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKF 235 L T A+N A+V G + G GGVG A+ K G + + Sbjct: 133 SLPTAGLTAL-QALNQAEVKQGDVVLIHAGAGGVGHLAIQLAKQKG--TTVITTASKRNH 189 Query: 236 VKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSC 295 KALGA C+N + ++ ++ ++ VD +D GG + ++DC G Sbjct: 190 AFLKALGAEQCINYHE-----EDFLLAISTP-VDAVIDLVGGDVGI-QSIDCLKE-TGCI 241 Query: 296 TFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHT 355 + + + E+ + +++ + L K ++ ++ Sbjct: 242 VSVPTITAGRVI-----EVAKQKHRRAFGLLKQFNIEELHYLGKLVSEDKLRIE--ISRI 294 Query: 356 LPFDKISEAFDLMNQGKSVRTILIF 380 + A +L+ G VR L+F Sbjct: 295 FQLSEAVTAHELLETGH-VRGKLVF 318 >4A27-A nrPDB Length = 349 Score = 121 bits (303), Expect = 5e-28, Method: Composition-based stats. Identities = 69/400 (17%), Positives = 121/400 (30%), Gaps = 90/400 (22%) Query: 8 IKCKAAIAWEAGK--PLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFP 64 ++ +A + G L + + P+ E++I++ A L D V + P Sbjct: 2 MEMRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTP 61 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 ++ G E +GIVE++G V + GD+V+ Sbjct: 62 LVPGFECSGIVEALGDSVKGYEIGDRVMA------------------------------- 90 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFST 184 F + +++ + KI DD + F T Sbjct: 91 ---------------------FVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVT 129 Query: 185 GYGAAINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 Y A + G + V GGVG + C + G ++ K K Sbjct: 130 AYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGT-ASTFKHEAIK---- 184 Query: 244 TDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG---- 299 + D + + + ++ GVD LDC G T L G+ G Sbjct: 185 DSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNT-GKGLSLLKP-LGTYILYGSSNM 242 Query: 300 VAAGSKGLTIFPEELII------------GRTINGTFFGGWKSVDS--------IPKLVT 339 V +K F + + I G + KL+ Sbjct: 243 VTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIG 302 Query: 340 DYKNKKFNLDALVTHTLPFDKISEAFDLMN-QGKSVRTIL 378 Y KK +V +++ EA ++ +G + IL Sbjct: 303 LYNQKKI--KPVVDSLWALEEVKEAMQRIHDRGNIGKLIL 340 >4IDE-A nrPDB Length = 332 Score = 120 bits (301), Expect = 1e-27, Method: Composition-based stats. Identities = 69/377 (18%), Positives = 124/377 (32%), Gaps = 78/377 (20%) Query: 11 KAAIAWEAGKP---LCIEE-VEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL--AFP 64 KA + E GK L + V V K +V I+++A SL D F+ P Sbjct: 25 KAWVYSEYGKTSDVLKFDPSVAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLP 84 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 I G++ AG+V +G VT K GD+V Sbjct: 85 TIPGYDVAGVVVKVGSQVTKFKVGDEVYGDLN---------------------------- 116 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFST 184 + +RF + ++YT + LA + + L T Sbjct: 117 --ETALVNPTRF-------------GSLAEYTAADERVLAHKPKNLSFIEAASLPLAIET 161 Query: 185 GYGAAINNAKVTPGSTCAVFGLGGVGLSAV-MGCKAAGASRIIGIDINSEKFVKAKALGA 243 + A+++ G + V G G + + K + + +++K + LGA Sbjct: 162 A-HEGLERAELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKVAATASTKKLDLLRTLGA 220 Query: 244 TDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAG 303 ++ +E +L + D D G + A+ G T +G Sbjct: 221 DLAIDYT------KENFEDLPE-KFDVVYDAVGET---DKAVKAVKEGGKVVTIVG---- 266 Query: 304 SKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISE 363 P ++ T G+ + KL ++ K T PF K+ E Sbjct: 267 ----PATPPAILFVLTSKGSV---------LEKLKPYLESGKVKPVLDPTSPYPFTKVVE 313 Query: 364 AFDLMNQGKSVRTILIF 380 AF + ++ ++++ Sbjct: 314 AFGYLESSRATGKVVVY 330 >4EYE-A nrPDB Length = 342 Score = 119 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 72/379 (18%), Positives = 130/379 (34%), Gaps = 66/379 (17%) Query: 8 IKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-GLAFPVI 66 +K A + + L +VE + V + + A +C D + +++ + P + Sbjct: 22 MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFV 81 Query: 67 VGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 G E AG+V S G + +KPGD+V+ Sbjct: 82 PGIETAGVVRSAPEG-SGIKPGDRVMA--------------------------------- 107 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY 186 F +++ V+ N+ + L + T Y Sbjct: 108 -------------------FNFIGGYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMY 148 Query: 187 GAAINNAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245 A ++ G T V GG+G +A+ K GA ++I + + K++GA Sbjct: 149 FAYARRGQLRAGETVLVLGAAGGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADI 207 Query: 246 CLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGS 304 L L + + + E T G GVD +D GG A+ T A G +G AAG Sbjct: 208 VL---PLEEGWAKAVREATGGAGVDMVVDPIGGP-AFDDAVR-TLASEGRLLVVGFAAGG 262 Query: 305 KGLTIFPEELIIGRTINGTFFGGW-KSVDSIPKLVTDYKNKKF--NLDALVTHTLPFDKI 361 L+ ++ G +G + ++ K + V+ +P + Sbjct: 263 IPTIKVNRLLLRNASLIGVAWGEFLRTHADYLYETQAGLEKLVAEGMRPPVSARIPLSEG 322 Query: 362 SEAFDLMNQGKS-VRTILI 379 +A GK + +L+ Sbjct: 323 RQALQDFADGKVYGKMVLV 341 >5A3V-A nrPDB Length = 329 Score = 114 bits (285), Expect = 8e-26, Method: Composition-based stats. Identities = 70/370 (18%), Positives = 118/370 (31%), Gaps = 75/370 (20%) Query: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDS---KFEGLAFPVIVGHEAAGIVESI 78 L +V V PK++EV +++ ATSL D + F FP I + AG V + Sbjct: 21 LEHVQVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEV 80 Query: 79 GPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138 G GV N K GDKV+ + + Sbjct: 81 GSGVKNFKAGDKVVAVLS------------------------------------------ 98 Query: 139 KGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPG 198 G +++ V ++ K + L T A N A + Sbjct: 99 -------HLGGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLD 151 Query: 199 ST-----CAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL 252 T V GGVG AV K A A + + K+LGA + L+ + Sbjct: 152 GTGKKANILVTAASGGVGHYAVQLAKLANA-HVTAT-CGARNIEFVKSLGADEVLDYKT- 208 Query: 253 HKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPE 312 P + + D + CA G + + + G I + G + + Sbjct: 209 --PEGAALKSPSGKKYDAVVHCANG--IPFSVFEPNLSENGKV--IDITPGPNAMWTYAV 262 Query: 313 ELIIGRT---INGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMN 369 + I + ++++ + LV + K K + P K +A+ Sbjct: 263 KKITMSKKQLVPLLLIPKAENLEFMVNLVKEGKVKTV-----IDSKHPLSKAEDAWAKSI 317 Query: 370 QGKSVRTILI 379 G + I++ Sbjct: 318 DGHATGKIIV 327 >3FBG-A nrPDB Length = 346 Score = 112 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 57/288 (19%), Positives = 96/288 (33%), Gaps = 64/288 (22%) Query: 19 GKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESI 78 G +++ PK HE+ ++I + S+ D + P ++G +A G+VES+ Sbjct: 17 GNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTK--QRLMDVSKAPRVLGFDAIGVVESV 74 Query: 79 GPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138 G VT GD V + SP N Sbjct: 75 GNEVTMFNQGDIV-----------YYSGSPDQN--------------------------- 96 Query: 139 KGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVT-- 196 + ++Y ++++ +AK + + E+ L T Y + ++ Sbjct: 97 -----------GSNAEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFGISRN 145 Query: 197 ----PGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRD 251 G T + G GGVG A KA G R+I +E K +GA LN ++ Sbjct: 146 RNENEGKTLLIINGAGGVGSIATQIAKAYG-LRVITTASRNETIEWTKKMGADIVLNHKE 204 Query: 252 -LHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFI 298 L + IEL VD+ + T + Sbjct: 205 SLLNQFKTQGIEL----VDYVFCTFNTDMYYDDMIQLVKPRGHIATIV 248 >2WEK-A nrPDB Length = 341 Score = 111 bits (278), Expect = 4e-25, Method: Composition-based stats. Identities = 62/375 (16%), Positives = 117/375 (31%), Gaps = 79/375 (21%) Query: 26 EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKF-EGLAFPVIVGHEAAGIVESIGPGVTN 84 + V P ++ ++ + +D ++ + P +G E G V ++G Sbjct: 24 DCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALG----- 78 Query: 85 VKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVY 144 ++R+T Y Sbjct: 79 ---------------------------------------------LSASARYTVGQAVAY 93 Query: 145 HFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF 204 +F++YTVV + L +T Y + ++ G V Sbjct: 94 --MAPGSFAEYTVVPASIATPVPSVKP--EYLTLLVSGTTAYISLKELGGLSEGKKVLVT 149 Query: 205 GL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIEL 263 GG G A+ K A +IG + EK K+LG +N + +P+ V+ + Sbjct: 150 AAAGGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLGCDRPINYKT--EPVGTVLKQE 206 Query: 264 TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL---------TIFPEEL 314 GVD + GG A+D A G IG +G + T+ + L Sbjct: 207 YPEGVDVVYESVGG-AMFDLAVDAL-ATKGRLIVIGFISGYQTPTGLSPVKAGTLPAKLL 264 Query: 315 IIGRTINGTFFGGW--KSVDSIPKLVTDYKNKKFNLDALVTHTLP------FDKISEAFD 366 ++ G F + K ++ L+ + + + P + I A + Sbjct: 265 KKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESIFRAVN 324 Query: 367 LMNQGK-SVRTILIF 380 M GK + + ++ Sbjct: 325 YMYMGKNTGKIVVEL 339 >3SLK-A nrPDB Length = 795 Score = 110 bits (275), Expect = 1e-24, Method: Composition-based stats. Identities = 72/365 (19%), Positives = 123/365 (33%), Gaps = 67/365 (18%) Query: 19 GKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESI 78 G L E AP EVRI + A + DA + + G+A +G E AG+V Sbjct: 223 GLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMYPGVAS---LGSEGAGVVVET 279 Query: 79 GPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138 GPGVT + PGD+V+ + Sbjct: 280 GPGVTGLAPGDRVMGMIPKA---------------------------------------- 299 Query: 139 KGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPG 198 FG + + +V+ I + R + F T Y A ++ A + PG Sbjct: 300 --------FGPLAVADHRMVTR-----IPAGWSFARAASVPIVFLTAYYALVDLAGLRPG 346 Query: 199 STCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 + V GGVG++A+ + GA + + +K+ A L + R + Sbjct: 347 ESLLVHSAAGGVGMAAIQLARHLGAE--VYATASEDKWQ-AVELSREHLASSRTC--DFE 401 Query: 258 EVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELII 316 + + T G GVD L+ G A+L G G +G + + + Sbjct: 402 QQFLGATGGRGVDVVLNSLAGEFA-DASLRMLPRG-GRFLELGKTDVRDPVEVADAHPGV 459 Query: 317 GRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQG-KSVR 375 T G + + + + + + L+ L + EA ++Q + Sbjct: 460 SYQAFDTVEAGPQRIGEMLHELVELFEGRV-LEPLPVTAWDVRQAPEALRHLSQARHVGK 518 Query: 376 TILIF 380 +L Sbjct: 519 LVLTM 523 >3B70-A nrPDB Length = 371 Score = 108 bits (270), Expect = 4e-24, Method: Composition-based stats. Identities = 65/377 (17%), Positives = 112/377 (29%), Gaps = 78/377 (20%) Query: 23 CIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGV 82 +V +++ A ++ +D + AF +G + AG V ++G V Sbjct: 25 VWNAAPCPMLPRDQVYVRVEAVAINPSDTKMRGQFATPWAF---LGTDYAGTVVAVGSDV 81 Query: 83 TNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKP 142 T+++ GD+V +C Sbjct: 82 THIQVGDRVYGAQNEMC------------------------------------------- 98 Query: 143 VYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGST-- 200 FSQYTV AKI + E+ L G ST A P + Sbjct: 99 -PRTPDQGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTAGLAMKLLGLPLPSPSAD 157 Query: 201 ----------CAVFGLG-GVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNP 249 V+G + + +G I + F AK+ GA + + Sbjct: 158 QPPTHSKPVYVLVYGGSTATATVTMQMLRLSGYIPIA--TCSPHNFDLAKSRGAEEVFDY 215 Query: 250 RDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL-T 308 R + + + I TK + +ALDC E+ G + Sbjct: 216 RAPN--LAQTIRTYTKNNLRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRK 273 Query: 309 IFPEELIIGRTINGT--------FFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP--- 357 + + +G TI G G + + + + LV H L Sbjct: 274 MVTTDWTLGPTIFGEGSTWPAPYGRPGSEEERQFGEDLWRIAGQLVEDGRLVHHPLRVVQ 333 Query: 358 --FDKISEAFDLMNQGK 372 FD I + +L+ +G+ Sbjct: 334 GGFDHIKQGMELVRKGE 350 >3QWB-A nrPDB Length = 334 Score = 108 bits (269), Expect = 5e-24, Method: Composition-based stats. Identities = 64/368 (17%), Positives = 108/368 (29%), Gaps = 70/368 (19%) Query: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPG 81 + E+ V E+ I+ T + + ++ + Sbjct: 23 IKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYP---------------------- 60 Query: 82 VTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGK 141 C K L AS + + K G Sbjct: 61 -------------------------------CEKPYVLGREASGTVVAKGKGVTNFEVGD 89 Query: 142 PVYHFFGTSTFSQY-TVVSDINLAKIDDDANLERVCLLGCGFS---TGYGAAINNAKVTP 197 V + STF+QY + S + K+ + E + L G T V Sbjct: 90 QVA-YISNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKK 148 Query: 198 GSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 G +F GGVGL K GA I + EK AK GA +N + I Sbjct: 149 GDYVLLFAAAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINAS--KEDI 205 Query: 257 QEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELI 315 +++ T G GVD + D G +T + +L +F + +I Sbjct: 206 LRQVLKFTNGKGVDASFDSVG-KDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLSPK 264 Query: 316 IGRTINGTFFGGWKSVDSI----PKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQG 371 + +G + + +KK N+ + T P A + Sbjct: 265 NITLVRPQLYGYIADPEEWKYYSDEFFGLVNSKKLNIK--IYKTYPLRDYRTAAADIESR 322 Query: 372 KSVRTILI 379 K+V +++ Sbjct: 323 KTVGKLVL 330 >2VWH-A nrPDB Length = 357 Score = 105 bits (263), Expect = 3e-23, Method: Composition-based stats. Identities = 70/388 (18%), Positives = 132/388 (34%), Gaps = 52/388 (13%) Query: 11 KAAIAWEAGK-PLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVI---DSKFEGLAFPVI 66 AIA + G+ + E P++ E ++ + + TD VI F ++ Sbjct: 1 MKAIAVKRGEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHGGFPEGEDHLV 60 Query: 67 VGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 +GHEA G+V P T ++ GD V+P S Sbjct: 61 LGHEAVGVVVD--PNDTELEEGDIVVPTVRR----------------PPASGTNEYFERD 102 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDAN-----LERVCLLGCG 181 Q + +G H S++ + L +I +E + + Sbjct: 103 QPDMAPDGMYFERGIVGAH----GYMSEFFTSPEKYLVRIPRSQAELGFLIEPISITEKA 158 Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAA--GASRIIGI---DINSEKFV 236 Y A+ + P S+ V G G +GL + K G + + D Sbjct: 159 LEHAY-ASRSAFDWDP-SSAFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTID 216 Query: 237 KAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCT 296 + L AT + + + + +V ++ DF + G + ++ G Sbjct: 217 IIEELDATYVDSRQTPVEDVPDVYEQM-----DFIYEATGFPKHAIQSVQALAP-NGVGA 270 Query: 297 FIGVAA----GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALV 352 +GV + E ++ + + G+ + ++ VT K K+ L+ LV Sbjct: 271 LLGVPSDWAFEVDAGAFHREMVLHNKALVGSVNSHVEHFEAA--TVTFTKLPKWFLEDLV 328 Query: 353 THTLPFDKISEAFDLMNQGKSVRTILIF 380 T P + AFD + +++T + F Sbjct: 329 TGVHPLSEFEAAFD--DDDTTIKTAIEF 354 >2CDC-A nrPDB Length = 366 Score = 104 bits (259), Expect = 6e-23, Method: Composition-based stats. Identities = 60/388 (15%), Positives = 120/388 (30%), Gaps = 60/388 (15%) Query: 11 KAAIAWEAGKPLCIEEVEVAPPKA-HEVRIQIIATSLCHTDATVIDSKFEGLAFP----- 64 KA I + +++V+ + +++I+ I +C D +++ K P Sbjct: 2 KAIIVKPPNAGVQVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKGKDF 61 Query: 65 VIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS 124 +++GHEA G+VE G GD V+P+ C C+ CL + C Sbjct: 62 LVLGHEAIGVVEESYHG---FSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEF------ 112 Query: 125 DQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFST 184 G+ H ++ L KI E + +L + Sbjct: 113 ---------------GEAGIHKM-DGFMREWWYDDPKYLVKIPKSI--EDIGILAQPLAD 154 Query: 185 GYGAAINNAKVTP---------GS----TCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN 231 + +V G+ V G G +G+ + + G + Sbjct: 155 IEKSIEEILEVQKRVPVWTCDDGTLNCRKVLVVGTGPIGVLFTLLFRTYGLEVWMANRRE 214 Query: 232 SEKFVK-AKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTA 290 + + T+ N + + +++ + G D +D G + + Sbjct: 215 PTEVEQTVIEETKTNYYNSSNGYDKLKDSV-----GKFDVIIDATGADVNILGNVIPLLG 269 Query: 291 GWGSCTFIGVAAGSKGLTIFPEE---LIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFN 347 G G + + + +TI G G +V K Sbjct: 270 RNGVLGLFGFSTSGSVPLDYKTLQEIVHTNKTIIGLVNGQKPHFQQA--VVHLASWKTLY 327 Query: 348 LDA---LVTHTLPFDKISEAFDLMNQGK 372 A L+T T+ + E ++ + + Sbjct: 328 PKAAKMLITKTVSINDEKELLKVLREKE 355 >5LB9-A nrPDB Length = 385 Score = 92.1 bits (227), Expect = 4e-19, Method: Composition-based stats. Identities = 64/403 (15%), Positives = 121/403 (30%), Gaps = 77/403 (19%) Query: 7 VIKCKAAIAWEAGKPLCIE-----EVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFE-- 59 +I +A + + G+P + E++ +EV ++ + + + +D I + Sbjct: 22 MITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVYPSK 81 Query: 60 -------GLAFPVIV-GHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTN 111 G P G+E V +G V++++ GD VIP N Sbjct: 82 PAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPS--------------HVN 127 Query: 112 LCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDAN 171 ++ D + + + Sbjct: 128 FGTWRTHALGNDDDFIKLPNPAQSKANGK--------------------------PNGLT 161 Query: 172 LERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF--GLGGVGLSAVMGCKAAGASRIIGID 229 + + + Y + K+TPG + G VG A K + I I Sbjct: 162 INQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIR 221 Query: 230 INS---EKFVKAKALGATDCL-----NPRDLHKPIQEVIIELTKGGVDFALDCAGGSETM 281 E K LGAT + N R+ I+E I + + G AL+C GG + Sbjct: 222 DRPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQ-SGGEAKLALNCVGGKSST 280 Query: 282 KAALDCTTAGWGSCTFIGVAAGSKGLT----IFPEELIIGRTINGTFFGGWKS-VDSIPK 336 A G T+ G++ + IF G + + ++ + Sbjct: 281 GIARKLNNNGL-MLTYGGMSFQPVTIPTSLYIFKNFTSAGFWVTELLKNNKELKTSTLNQ 339 Query: 337 LVTDYKNKKFNLDALVTHTL----PFDK-ISEAFDLMNQGKSV 374 ++ Y+ K + P + + GK + Sbjct: 340 IIAWYEEGKLTDAKSIETLYDGTKPLHELYQDGVANSKDGKQL 382 >1V3V-A nrPDB Length = 333 Score = 82.5 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 44/233 (18%), Positives = 77/233 (33%), Gaps = 20/233 (8%) Query: 160 DINLAKIDDDANLERV-CLLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGVGLSAVMGC 217 + L + D L +G T Y + V G T V G VG Sbjct: 107 EKLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIA 166 Query: 218 KAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGG 277 K G +++G + EK K +G N + ++ ++E + + + G D D GG Sbjct: 167 KLKG-CKVVGAAGSDEKIAYLKQIGFDAAFNYKTVNS-LEEALKKASPDGYDCYFDNVGG 224 Query: 278 SETMKAALDCTTAGWGSCTFIG----------VAAGSKGLTIFPEELIIGRTINGTFFGG 327 + +G G + G +I ++L I I + G Sbjct: 225 E--FLNTVLSQMKDFGKIAICGAISVYNRMDQLPPGPSPESIIYKQLRIEGFIVYRWQGD 282 Query: 328 WKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKS-VRTILI 379 + + L+ K VT F+ + AF M G + + ++ Sbjct: 283 VREKA-LRDLMKWVLEGKIQYHEHVTKG--FENMPAAFIEMLNGANLGKAVVT 332 >3WID-A nrPDB Length = 369 Score = 79.8 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 61/374 (16%), Positives = 117/374 (31%), Gaps = 58/374 (15%) Query: 12 AAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLAFP-----VI 66 A + + ++++ P+ +E +++ + +C TD + P ++ Sbjct: 6 AIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLV 65 Query: 67 VGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 126 +GHEA V + +K GD V+PL KC C + C Sbjct: 66 LGHEALLQVLDV-SDNNYIKRGDFVVPLVRRP-GKCVNCRIGRQDNCSIGD--------- 114 Query: 127 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDI-NLAKIDDDANLERVCLLGCGFSTG 185 K G F + + DI NL K++D +L ++ +L Sbjct: 115 ------------PDKHEAGITGLHGFMRDVIYDDIQNLVKVNDP-DLGKIAVLTEPLKNV 161 Query: 186 YGAAINNAKVTP------------GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSE 233 A V+ G V G G K G + ++ + E Sbjct: 162 MKAFEVFDVVSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRG-FDVTMVNRHDE 220 Query: 234 KFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWG 293 K K + + + K + + I D +D +G T+ + G Sbjct: 221 TENKMKMMD-DFGVGFSNYLKDMPDKI--------DLLVDTSGDPSTIFKFVKKVN-NNG 270 Query: 294 SCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGG-----WKSVDSIPKLVTDYKNKKFNL 348 G + G + E++ N T G V ++ L Y + Sbjct: 271 VVILFGFNGKAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTI 330 Query: 349 DALVTHTLPFDKIS 362 ++T+ ++ + Sbjct: 331 KDIITYEAKPEETN 344 >5GXF-A nrPDB Length = 330 Score = 74.8 bits (182), Expect = 7e-14, Method: Composition-based stats. Identities = 49/269 (18%), Positives = 88/269 (32%), Gaps = 65/269 (24%) Query: 9 KCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTD-ATVIDSKFEGLAFPVIV 67 K +AA+ K L + ++ V EV + + +++ + D + +P + Sbjct: 15 KTQAAV-----KQLSLTDLPV-----GEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVP 64 Query: 68 GHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQ 127 G + AG VE+ KPGDKV+ + Sbjct: 65 GIDFAGTVEN--SSDERYKPGDKVVLTGW---------RVGEAHW--------------- 98 Query: 128 LMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYG 187 +SQ V L + + + + +G T Sbjct: 99 ----------------------GGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAML 136 Query: 188 A--AINNAKVTPGS-TCAVFG-LGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA 243 A A+ + +TPG V G GGVG A G + + E +LGA Sbjct: 137 AVMALEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLG-YEVAAVTGRPETADYLTSLGA 195 Query: 244 TDCLNPRDLHKPIQEVI-IELTKGGVDFA 271 T + ++++ ++ + E+ G VD Sbjct: 196 TQIVARDEINETVKRPLESEIWAGCVDAV 224 >2Y05-A nrPDB Length = 328 Score = 73.6 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 39/231 (16%), Positives = 70/231 (30%), Gaps = 17/231 (7%) Query: 160 DINLAKIDDDANLERV-CLLGCGFSTGYGAAINNAKVTPGSTCAV-FGLGGVGLSAVMGC 217 + L + D L +G T Y + V G T V G VG Sbjct: 102 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 161 Query: 218 KAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGG 277 K G +++G + EK + LG N + + + ++E + + + G D D GG Sbjct: 162 KLKG-CKVVGAVGSDEKVAYLQKLGFDVVFNYKTV-ESLEETLKKASPDGYDCYFDNVGG 219 Query: 278 SETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTING--------TFFGGWK 329 + +G G + P I + Sbjct: 220 E--FSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGD 277 Query: 330 SVDSIPK-LVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILI 379 + K L+ K + F+ + AF M +G ++ ++ Sbjct: 278 ARQKALKDLLKWVLEGKIQYKEYIIEG--FENMPAAFMGMLKGDNLGKTIV 326 >1O89-A nrPDB Length = 345 Score = 68.6 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 57/327 (17%), Positives = 105/327 (32%), Gaps = 64/327 (19%) Query: 23 CIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGLA-FPVIVGHEAAGIVESIGPG 81 ++ ++ + +V + + +SL + DA I K + + FP+I G + AG V + Sbjct: 37 SVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRT--SE 94 Query: 82 VTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGK 141 G +V+ G Sbjct: 95 DPRFHAGQEVLLTGW-------------------------------------------GV 111 Query: 142 PVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGA--AINNAKVTP-- 197 H+ ++ V L + + + ++G T A+ +A V P Sbjct: 112 GENHW---GGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQD 168 Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 G GGVG +AV G +++ + K+LGA+ L PRD + Sbjct: 169 GEIVVTGASGGVGSTAVALLHKLG-YQVVAVSGRESTHEYLKSLGASRVL-PRDEFAESR 226 Query: 258 EVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG 317 + ++ G A+D G + + L G G G+A G T ++ Sbjct: 227 PLEKQVWAG----AIDTVGD-KVLAKVLAQMNYG-GCVAACGLAGGFTLPTTVMPFILRN 280 Query: 318 RTING---TFFGGWKSVDSIPKLVTDY 341 + G + + +LV D Sbjct: 281 VRLQGVDSVMTPPERRAQAWQRLVADL 307 >2J3K-A nrPDB Length = 345 Score = 64.0 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 50/275 (18%), Positives = 83/275 (30%), Gaps = 24/275 (8%) Query: 123 ASDQQLMEDKTSRFTCKGKPVYHFF----GTSTFSQYTVVSDINLAKID---DDANLERV 175 Q + SR G P Y G + +Y+V++ + A D L Sbjct: 73 TPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYY 132 Query: 176 C-LLGCGFSTGYGAAINNAKVTPGSTCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSE 233 LLG T Y G T V G VG K G ++G + E Sbjct: 133 TGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCY-VVGSAGSKE 191 Query: 234 KFVKAK-ALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGW 292 K K G D N ++ + + G+D + GG M A+ Sbjct: 192 KVDLLKTKFGFDDAFNYKE-ESDLTAALKRCFPNGIDIYFENVGGK--MLDAVLVNMNMH 248 Query: 293 GSCTFIGVAAG-----SKGLTIFPEELIIGRTINGTFFGGW--KSVDSIPKLVTDYKNKK 345 G G+ + +G+ + I G + K + ++ + K Sbjct: 249 GRIAVCGMISQYNLENQEGVHNLSNIIYKRNRIQGFVVSDFYDKYSKFLEFVLPHIREGK 308 Query: 346 FNLDALVTHTLPFDKISEAF-DLMNQGKSVRTILI 379 V +K EA L + + +++ Sbjct: 309 ITYVEDVADG--LEKAPEALVGLFHGKNVGKQVVV 341 >2VNA-A nrPDB Length = 357 Score = 59.0 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 52/299 (17%), Positives = 93/299 (31%), Gaps = 29/299 (9%) Query: 101 KCKFCL-SPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVS 159 +C+ + + + ++E+ KG V F+ + ++ Sbjct: 54 RCRMNEDTGTDYITPWQLSQVVDGGGIGIIEESKHTNLTKGDFVTSFYWP--WQTKVILD 111 Query: 160 DINLAKIDDDANLERV----CLLGCGFSTGYGAAINNAKVTPGS--TCAVFGL-GGVGLS 212 +L K+D + +G T +T GS T V G G G Sbjct: 112 GNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSV 171 Query: 213 AVMGCKAAGASRIIGI-DINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFA 271 A G SR++GI + + + LG +N + + E + E GVD Sbjct: 172 AGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYK--KDNVAEQLRESCPAGVDVY 229 Query: 272 LDCAGGSETMKAALDCTTAGWGSCTFIGVAAG-----SKGLTIFPEELIIGRTINGT--- 323 D GG + + G + + P I + N T Sbjct: 230 FDNVGG--NISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRER 287 Query: 324 -FFGGWKSVDS--IPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD-LMNQGKSVRTIL 378 +K I +L +K K + V + + + AF +M G + I+ Sbjct: 288 FLVLNYKDKFEPGILQLSQWFKEGKLKIKETVING--LENMGAAFQSMMTGGNIGKQIV 344 >2ZB3-A nrPDB Length = 353 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 52/292 (17%), Positives = 87/292 (29%), Gaps = 28/292 (9%) Query: 107 SPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKI 166 + L + ++E+ + KG V F+ + ++ L K+ Sbjct: 62 TGTDYLAPWQLAQVADGGGIGVVEESKHQKLTKGDFVTSFYWP--WQTKAILDGNGLEKV 119 Query: 167 DDDANLERV----CLLGCGFSTGYGAAINNAKVTPGS--TCAVFGL-GGVGLSAVMGCKA 219 D + +G T ++ GS T V G G G A Sbjct: 120 DPQLVDGHLSYFLGAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHL 179 Query: 220 AGASRIIGI-DINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGS 278 G SR++GI + LG +N + + + E + E GGVD D GG Sbjct: 180 LGCSRVVGICGTQEKCLFLTSELGFDAAVNYKTGN--VAEQLREACPGGVDVYFDNVGGD 237 Query: 279 ETMKAALDCTTAGWGSCTFIG-----------VAAGSKGLTIFPEELIIGRTINGTFFGG 327 + A+ G + +E I R Sbjct: 238 --ISNAVISQMNENSHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVLNYK 295 Query: 328 WKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFD-LMNQGKSVRTIL 378 K I +L +K K + T + + AF +M G + I+ Sbjct: 296 DKFEPGILQLSQWFKEGKLKVKE--TMAKGLENMGVAFQSMMTGGNVGKQIV 345 >1ZCJ-A nrPDB Length = 463 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVG-LSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 ST GA+ A P S+ V GLG +G A+ + ++ ++ + ++ AK + Sbjct: 22 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 79 >3ZWA-A nrPDB Length = 742 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVG-LSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 ST GA+ A P S+ V GLG +G A+ + ++ ++ + ++ AK + Sbjct: 301 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 358 >4DIO-A nrPDB Length = 405 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 49/144 (34%), Gaps = 14/144 (9%) Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLN 248 + A P + V G G GL A+ + GA + D+ + +LGA + Sbjct: 181 MMTAAGTVPAAKIFVMGAGVAGLQAIATARRLGA-VVSATDVRPAAKEQVASLGAK-FIA 238 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 D E T GG +A + +G + +AAL + + Sbjct: 239 VEDEEFKAAE-----TAGG--YAKEMSGEYQVKQAALVAEHIAKQDIVI-----TTALIP 286 Query: 309 IFPEELIIGRTINGTFFGGWKSVD 332 P ++ R + + G VD Sbjct: 287 GRPAPRLVTREMLDSMKPGSVVVD 310 >3MGG-A nrPDB Length = 276 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 37/108 (34%), Gaps = 9/108 (8%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL-NPRDLHKP 255 PG+ G G +G V+ K + I IDI+ E KA+ + + N + L Sbjct: 37 PGAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQAN 95 Query: 256 IQEVIIELTKGGVDFALDCAG-----GSETMKAALDCTTAGWGSCTFI 298 I + E D C E +L G+ T I Sbjct: 96 IFSLPFE--DSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >2EGU-A nrPDB Length = 308 Score = 40.9 bits (94), Expect = 9e-04, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 188 AAINNAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 245 AA K+ PG T G G+GL+ V K A ++ ++ E+ +A GA Sbjct: 55 AAEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAEL 114 Query: 246 CLNP 249 L P Sbjct: 115 VLTP 118 >5ILO-A nrPDB Length = 271 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 33/86 (38%), Gaps = 12/86 (13%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT----------DCLNPR 250 G GG+GL AAGA+++ ID+ K A D N + Sbjct: 19 VVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKK 78 Query: 251 DLHKPIQEVIIELTKGGVDFALDCAG 276 + +E+ T G +D ++ AG Sbjct: 79 GVEATYEEIAK--TFGNIDIVVNVAG 102 >1BW9-B nrPDB Length = 356 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 38/164 (23%), Positives = 53/164 (32%), Gaps = 13/164 (7%) Query: 171 NLERVCLLGCGFSTGYGA--------AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA 222 +LER F+T G A G T V GLG VG S AGA Sbjct: 141 SLERGGAGSSAFTTAVGVFEAMKATVAHRGLGSLDGLTVLVQGLGAVGGSLASLAAEAGA 200 Query: 223 SRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG----GVDFALDCAGGS 278 +++ D ++E+ A ALG T L P G V LDC+ + Sbjct: 201 -QLLVADTDTERVAHAVALGHTAVALEDVLSTPCDVFAPCAMGGVITTEVARTLDCSVVA 259 Query: 279 ETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTING 322 + A + A ++GR + G Sbjct: 260 GAANNVIADEAASDILHARGILYAPDFVANAGGAIHLVGREVLG 303 >2VHY-A nrPDB Length = 377 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 30/115 (26%), Gaps = 14/115 (12%) Query: 166 IDDDANLERVCLLGCGFSTGYGAAINNAK----------VTPGSTCAVFGLGGVGLSAVM 215 + A + V Y V P V G G G +A Sbjct: 127 LPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPAD-VVVIGAGTAGYNAAR 185 Query: 216 GCKAAGASRIIGIDINSEKFVK--AKALGATDCLNPRDLHKPIQEVIIELTKGGV 268 GA + +DIN +K + A+ G +L G V Sbjct: 186 IANGMGA-TVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAV 239 >1XLT-A nrPDB Length = 384 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 185 GYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 + + A P + VFG+G GL A+ K GA ++ D+ + + ++LG Sbjct: 159 AFPMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLG 215 >1X14-A nrPDB Length = 401 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 1/59 (1%) Query: 186 YGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT 244 + I A P + V G G GL+A+ + GA + D E + +++GA Sbjct: 160 FTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGA-IVRAFDTRPEVKEQVQSMGAE 217 >1E3W-A nrPDB Length = 261 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL--HKPIQE 258 G G+GLS GA+ ++ NSE +AK LG P ++ K +Q Sbjct: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 Query: 259 V--IIELTKGGVDFALDCAGGSETMKA 283 + + G +D A++CAG + +K Sbjct: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKT 100 >6BII-A nrPDB Length = 333 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 32/184 (17%), Positives = 52/184 (28%), Gaps = 22/184 (11%) Query: 185 GYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA- 243 + + G T + G G +G + K G I S K K LGA Sbjct: 137 AWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGMR--ILYTARSRKPEAEKELGAE 194 Query: 244 -----------TDCLNPRDLHKP----IQEVIIELTKGGVDFALDCAGGSETMKAALDCT 288 + L K I E + L K G KA + Sbjct: 195 FKPLEELLRESDFVVLAVPLTKETYHMINEERLRLMKPTAVLVNVARGKVVDTKALIRAL 254 Query: 289 TAGWGSCTFIGVA---AGSKGLTIFPEELIIGRTINGTFFGGWKSVDS-IPKLVTDYKNK 344 GW + + V + +++ I FG + + + K + +KN Sbjct: 255 KEGWIAAAGLDVFEEEPYYDEELFALDNVVLTPHIGSATFGAREGMAELVAKNLIAFKNG 314 Query: 345 KFNL 348 + Sbjct: 315 EVPP 318 >1I9G-A nrPDB Length = 280 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 33/203 (16%), Positives = 66/203 (32%), Gaps = 12/203 (5%) Query: 106 LSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDIN--L 163 + ++ ++ + + + F + H Q +VV N L Sbjct: 3 ATGPFSIGERVQLTDAKGRRYTMSLTPGAEFHTHRGSIAHDAVIG-LEQGSVVKSSNGAL 61 Query: 164 AKIDDDANLERVCLLGCGFSTGY----GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKA 219 + ++ V + G Y ++ + PG+ G G G + +A Sbjct: 62 FLVLRPLLVDYVMSMPRGPQVIYPKDAAQIVHEGDIFPGARVLEAGAGS-GALTLSLLRA 120 Query: 220 AG-ASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVII--ELTKGGVD-FALDCA 275 G A ++I + ++ A+ + P D + + + EL G VD LD Sbjct: 121 VGPAGQVISYEQRADHAEHARRNVSGCYGQPPDNWRLVVSDLADSELPDGSVDRAVLDML 180 Query: 276 GGSETMKAALDCTTAGWGSCTFI 298 E + A AG ++ Sbjct: 181 APWEVLDAVSRLLVAGGVLMVYV 203 >3X2F-A nrPDB Length = 411 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 37/104 (35%), Gaps = 14/104 (13%) Query: 179 GCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA 238 G G ST N + G V G G G + GA R+I +++ K Sbjct: 178 GTGQSTWDAIMRNTNLLVAGKNVVVAGYGWCGRGIALRAAGLGA-RVIVTEVDPVK---- 232 Query: 239 KALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMK 282 A + + P++E + DF + +G ++ + Sbjct: 233 ----AVEAIMDGFTVMPMKEAVKI-----ADFVITASGNTDVLS 267 >4XIJ-A nrPDB Length = 275 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 23/59 (38%), Gaps = 4/59 (6%) Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK----FVKAKALGA 243 + A T G + V G GG +AV+ G RI + + K A+ GA Sbjct: 117 GVTGALGTAGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARRCGA 175 >2B25-A nrPDB Length = 336 Score = 37.0 bits (84), Expect = 0.015, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 16/105 (15%) Query: 194 KVTPGSTCAVFGLGGVGLSAVMGCKAAGA-SRIIGIDINSEKFVKAKALGATDCLNPRDL 252 + PG T G G G ++ KA G+ R+I ++ + AK N + Sbjct: 102 DINPGDTVLEAGSGS-GGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK-------NYKHW 153 Query: 253 HKPIQEVIIELTKGGVDFAL-DCAGGSETMKA------ALDCTTA 290 + +E VDF D +G +E +K+ ALD Sbjct: 154 RDSWKLSHVEEWPDNVDFIHKDISGATEDIKSLTFDAVALDMLNP 198 >6C55-A nrPDB Length = 340 Score = 36.2 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 26/81 (32%), Gaps = 9/81 (11%) Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 +T Y G AV G G G + K G +IGI F KAK Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRS-FDKAKED 59 Query: 242 GATDCLNPRDLHKPIQEVIIE 262 G P+ E + + Sbjct: 60 GFDVF--------PVAEAVKQ 72 >5U9P-A nrPDB Length = 265 Score = 36.2 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 10/88 (11%) Query: 198 GSTCAVFGLG-GVGLSAVMGCKAAGASRIIGIDINSEKFV-KAKA-----LGATDCLNPR 250 G + G G G+GL+ G AGA+ +I D N EK A+ A + Sbjct: 20 GRRALITGSGRGIGLTLARGLAEAGAAIVIN-DRNEEKAATLARRFRDEGFAADHAVFDV 78 Query: 251 DLHKPIQEVIIELTK--GGVDFALDCAG 276 H ++ I E G +D ++ AG Sbjct: 79 AEHAQVRAAIDEFEARVGAIDILVNNAG 106 >1V9L-A nrPDB Length = 421 Score = 36.2 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 32/85 (37%), Gaps = 7/85 (8%) Query: 154 QYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAI-------NNAKVTPGSTCAVFGL 206 +Y+ + N+ + E ++TG+G A+ G T A+ G+ Sbjct: 159 EYSKIKGYNVPGVFTSKPPELWGNPVREYATGFGVAVATREMAKKLWGGIEGKTVAIQGM 218 Query: 207 GGVGLSAVMGCKAAGASRIIGIDIN 231 G VG + GA I DIN Sbjct: 219 GNVGRWTAYWLEKMGAKVIAVSDIN 243 >3VPX-A nrPDB Length = 364 Score = 35.9 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA-KALGATDC 246 G T AV G+G V + GA ++I DIN E +A A GAT Sbjct: 172 AGKTVAVQGVGNVAYALCEYLHEEGA-KLIITDINEEAVQRAVDAFGATAV 221 >5UYY-A nrPDB Length = 381 Score = 35.9 bits (81), Expect = 0.031, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 59/183 (32%), Gaps = 15/183 (8%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 + G G +G S + K I G DI E+ +AK L D + DL +E Sbjct: 18 KKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKELHVVDEI-AVDLQHACEE 76 Query: 259 VIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGR 318 + + ET K + + +KG + E + + Sbjct: 77 ---------AHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALFSK 127 Query: 319 TINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALV---THTLPFDKISEAFDLMNQGKSVR 375 I +F GG S V K F + H +P + + E D + S Sbjct: 128 EI--SFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMHHVPNEHVEELKDWLKGTGSHF 185 Query: 376 TIL 378 +L Sbjct: 186 LVL 188 >1V8B-A nrPDB Length = 479 Score = 35.9 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 43/143 (30%), Gaps = 16/143 (11%) Query: 179 GCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA 238 GC S G + G + G G VG K GA R+ +I+ ++A Sbjct: 238 GCRHSLPDGLMRATDFLISGKIVVICGYGDVGKGCASSMKGLGA-RVYITEIDPICAIQA 296 Query: 239 KALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFI 298 G + E+ G DF + C G + +K L+ + Sbjct: 297 VMEGFNVV------------TLDEIVDKG-DFFITCTGNVDVIK--LEHLLKMKNNAVVG 341 Query: 299 GVAAGSKGLTIFPEELIIGRTIN 321 + + + G I Sbjct: 342 NIGHFDDEIQVNELFNYKGIHIE 364 >2O23-A nrPDB Length = 265 Score = 35.9 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDL--HKPIQE 258 G G+GL+ GAS ++ NS +AK LG P D+ K +Q Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 259 --VIIELTKGGVDFALDCAG 276 + + G VD A++CAG Sbjct: 76 ALALAKGKFGRVDVAVNCAG 95 >5EKU-A nrPDB Length = 390 Score = 35.5 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 195 VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 VTP + G G GL ++M K GA ++ ++ + E A+ Sbjct: 93 VTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE 136 >4M36-A nrPDB Length = 343 Score = 35.5 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 195 VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 VTP + G G GL ++M K GA ++ ++ + E A+ Sbjct: 58 VTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE 101 >4K2X-A nrPDB Length = 523 Score = 35.5 bits (80), Expect = 0.040, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 5/72 (6%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT----DCLNPRDLHKPI 256 + G G GL + AGA R + ++ +E +KALG + L+ R L + Sbjct: 25 VVIAGAGPTGLMLACELRLAGA-RTLVLERLAEPVDFSKALGVHARTVELLDMRGLGEGF 83 Query: 257 QEVIIELTKGGV 268 Q +L G Sbjct: 84 QAEAPKLRGGNF 95 >3EBV-A nrPDB Length = 302 Score = 35.5 bits (80), Expect = 0.041, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 43/126 (34%), Gaps = 13/126 (10%) Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKA-------AGASRIIGIDINSEKFVKAKAL 241 A +A TPG+ G+G V KA AG II + + Sbjct: 36 AFADATTTPGAVTFNLDSAGLGGYTVDQFKADVRAKQAAGKKVIISVGGEKGTVSVNSSA 95 Query: 242 GATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 AT+ N + V+ E GVD L+ M AL +A G + +A Sbjct: 96 SATNFANS------VYSVMREYGFDGVDIDLENGLNPTYMTQALRALSAKAGPDMILTMA 149 Query: 302 AGSKGL 307 + + Sbjct: 150 PQTIDM 155 >1VH3-A nrPDB Length = 262 Score = 35.1 bits (79), Expect = 0.048, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 221 GASRIIGIDINSEKFVKAKALGATDC---LNPRDLHKPIQEVIIELTKGGVDFALDCAGG 277 GASR+I N AK+ GA C +N + + EV+ +L + ++ G Sbjct: 41 GASRVIIATDNENVADVAKSFGAEVCMTSVNHNSGTERLAEVVEKLAIPDNEIIVNIQGD 100 Query: 278 S 278 Sbjct: 101 E 101 >5JXW-A nrPDB Length = 498 Score = 34.7 bits (78), Expect = 0.064, Method: Composition-based stats. Identities = 20/127 (15%), Positives = 43/127 (33%), Gaps = 16/127 (12%) Query: 194 KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLH 253 ++ G V G G VG G GA R+I +I+ ++A G + Sbjct: 267 QMLAGKKIVVLGYGEVGKGCAQGLSGVGA-RVIVTEIDPICALQASMEGYQVSV------ 319 Query: 254 KPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEE 313 +++V+ E D + G + + ++ + + + ++ E Sbjct: 320 --LEDVVSE-----ADIFITATGNKDVI--TVEHMRKMKENAYIANIGHFDDEIDVYGLE 370 Query: 314 LIIGRTI 320 G + Sbjct: 371 NYPGIKV 377 >1DXY-A nrPDB Length = 333 Score = 34.7 bits (78), Expect = 0.065, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 19/53 (35%), Gaps = 2/53 (3%) Query: 186 YGAAINNAKVTPGS-TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVK 237 Y A G T V G G +G A+ K GA ++I D K Sbjct: 132 YEKAGTFIGKELGQQTVGVMGTGHIGQVAIKLFKGFGA-KVIAYDPYPMKGDH 183 >1ZFN-A nrPDB Length = 253 Score = 34.7 bits (78), Expect = 0.070, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 41/136 (30%), Gaps = 24/136 (17%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINS--------------EKFVKAKALGAT 244 S + GLGG+G A + AG ++ D + E + K+ + Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQ 90 Query: 245 DCLNPRDLHKPIQEVIIELTKGG-------VDFALDCAGGSET---MKAALDCTTAGWGS 294 L + + + LT D LDC T + AA + Sbjct: 91 QRLTQLNPDIQLTALQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLIT 150 Query: 295 CTFIGVAAGSKGLTIF 310 + +G LT Sbjct: 151 ASAVGFGGQLMVLTPP 166 >2HMT-A nrPDB Length = 144 Score = 34.7 bits (78), Expect = 0.071, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 29/79 (36%), Gaps = 5/79 (6%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 AV GLG G S V G ++ +DIN EK + AT + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEE---N 61 Query: 259 VIIELTKGGVDFALDCAGG 277 ++ L ++ + G Sbjct: 62 ELLSLGIRNFEYVIVAIGA 80 >4DIM-A nrPDB Length = 403 Score = 34.7 bits (78), Expect = 0.077, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 27/79 (34%), Gaps = 5/79 (6%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK--FVKAKALGATDCLNPRDLHKPI 256 + G G L K G I G N+ K A + D NP ++ + + Sbjct: 8 KRLLILGAGRGQLGLYKAAKELGIHTIAGTMPNAHKPCLNLADEISYMDISNPDEVEQKV 67 Query: 257 QEVIIELTKGGVDFALDCA 275 +++ + G LD Sbjct: 68 KDLNL---DGAATCCLDTG 83 >5BUT-A nrPDB Length = 288 Score = 34.3 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 29/79 (36%), Gaps = 5/79 (6%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 AV GLG G S V G ++ +DIN EK + AT + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEE---N 61 Query: 259 VIIELTKGGVDFALDCAGG 277 ++ L ++ + G Sbjct: 62 ELLSLGIRNFEYVIVAIGA 80 Score = 34.3 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 29/79 (36%), Gaps = 5/79 (6%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 AV GLG G S V G ++ +DIN EK + AT + + Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEE---N 203 Query: 259 VIIELTKGGVDFALDCAGG 277 ++ L ++ + G Sbjct: 204 ELLSLGIRNFEYVIVAIGA 222 >3TMA-A nrPDB Length = 354 Score = 34.3 bits (77), Expect = 0.096, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 6/70 (8%) Query: 174 RVCLLGCGFSTGYGAAINNAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGA-SRIIGIDI 230 + L G A + A PG G G + A+ G S + D+ Sbjct: 180 KAALRGSLTPVLAQALLRLADARPGMRVLDPFTGSGTI---ALEAASTLGPTSPVYAGDL 236 Query: 231 NSEKFVKAKA 240 + ++ A+ Sbjct: 237 DEKRLGLARE 246 >3LGA-A nrPDB Length = 253 Score = 33.9 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 41/128 (32%), Gaps = 20/128 (15%) Query: 172 LERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA-SRIIGIDI 230 + V Y A ++PG G+G G + G R++ +I Sbjct: 74 PQIVHPKDAALIVAY------AGISPGDFIVEAGVGS-GALTLFLANIVGPEGRVVSYEI 126 Query: 231 NSEKFVKA----KALGATD--CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAA 284 + A K G D + +D+++ I+E ++ LD ++ A Sbjct: 127 REDFAKLAWENIKWAGFDDRVTIKLKDIYEGIEEENVD------HVILDLPQPERVVEHA 180 Query: 285 LDCTTAGW 292 G Sbjct: 181 AKALKPGG 188 >3EGI-A nrPDB Length = 206 Score = 33.9 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 16/39 (41%), Gaps = 2/39 (5%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 239 V GVG + + R+I IDI+ K A+ Sbjct: 46 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 82 >3GDH-A nrPDB Length = 241 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 16/39 (41%), Gaps = 2/39 (5%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 239 V GVG + + R+I IDI+ K A+ Sbjct: 81 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 117 >1NVM-B nrPDB Length = 312 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 31/161 (19%), Positives = 57/161 (35%), Gaps = 16/161 (9%) Query: 200 TCAVFGLGGVGL-SAVMG---CKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKP 255 A+ G G +G + K ++GID S+ +A+ +G T + Sbjct: 6 KVAIIGSGNIGTDLMIKVLRNAKYLEMGAMVGIDAASDGLARAQRMGVT------TTYAG 59 Query: 256 IQEVIIELTKGGVDFALDCAGGSETMK--AALDCTTAGWGSCTFIGVAAGSKGLTIFPEE 313 ++ +I +DF D S ++ A L G A G + + E Sbjct: 60 VEGLIKLPEFADIDFVFDATSASAHVQNEALLRQAKPGIRLIDLTPAAIGPYCVPVVNLE 119 Query: 314 LIIGR-TINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVT 353 +G+ +N GG +IP + + K + +V Sbjct: 120 EHLGKLNVNMVTCGGQA---TIPMVAAVSRVAKVHYAEIVA 157 >3KYD-B nrPDB Length = 551 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 18/45 (40%) Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN 231 G A+ G V G GG+G + G S I ID++ Sbjct: 8 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 52 >3KYC-B nrPDB Length = 660 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 18/45 (40%) Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN 231 G A+ G V G GG+G + G S I ID++ Sbjct: 26 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 70 >5Z1Z-A nrPDB Length = 329 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 19/49 (38%), Gaps = 3/49 (6%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 G T V G G +G++ + K G R++ D A LG Sbjct: 144 GKTAGVIGTGKIGVAMLRILKGFGM-RLLAFDPYPS--AAALELGVEYV 189 >3OAM-A nrPDB Length = 252 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 46/140 (32%), Gaps = 10/140 (7%) Query: 184 TGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA-KALG 242 T A + PG A G + AGA R+I I + E+ +A +A G Sbjct: 4 TVVIPARYQSTRLPGKPLADIGGKPMIQWVYEQAMQAGADRVI-IATDDERVEQAVQAFG 62 Query: 243 ATDCL---NPRDLHKPIQEVIIELTKGGVDFALDCAGG-----SETMKAALDCTTAGWGS 294 C+ N + + + EV+ ++ ++ G ++ D A Sbjct: 63 GVVCMTSPNHQSGTERLAEVVAKMAIPADHIVVNVQGDEPLIPPAIIRQVADNLAACSAP 122 Query: 295 CTFIGVAAGSKGLTIFPEEL 314 + V + P + Sbjct: 123 MATLAVEIEDEAEVFNPNAV 142 >6CU3-A nrPDB Length = 336 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 14/104 (13%) Query: 177 LLGCGFST-GYGAAI-NNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK 234 +L G T Y AI N + G G G+ + KA GA R+IGID++ Sbjct: 29 MLKDGIRTNAYKNAILQNKHLFKDKVVLDIGCGT-GILCLFAAKA-GAKRVIGIDMSDI- 85 Query: 235 FVKAKAL----GATDCLNPRDLHKPIQEVIIELTKG--GVDFAL 272 KA+ + G + + +L K E I +L G VD + Sbjct: 86 IDKARQIVSDNGYSHVI---ELIKGKVEDIAQLPFGIEKVDIII 126 >4N7R-A nrPDB Length = 472 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 7/39 (17%), Positives = 18/39 (46%) Query: 202 AVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 V G G +G + A G ++++ ++ + E+ + Sbjct: 211 CVIGAGKMGKLVIKHLMAKGCTKVVVVNRSEERVSAIRE 249 >6GBN-A nrPDB Length = 438 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 30/85 (35%), Gaps = 14/85 (16%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 G V G G VG + + AGA R+I +I+ ++A A D + + + Sbjct: 218 AGKVAVVAGYGDVGKGSAASLRGAGA-RVIVTEIDPICALQA----AMDGYEVKKMADAV 272 Query: 257 QEVIIELTKGGVDFALDCAGGSETM 281 + D + G + Sbjct: 273 KR---------ADIVVTATGNKNII 288 >6FZI-A nrPDB Length = 332 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 41/133 (30%), Gaps = 20/133 (15%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGI-DINSEK-FVKAKAL---------------G 242 A+ G G +G A+ ++ I D+ K G Sbjct: 3 KVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVKEG 62 Query: 243 ATDCLNPRDLHKPIQEVIIELTKG--GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300 A +N +++ + EL G GVD L+C G + + A TAG Sbjct: 63 A-FVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVISAP 121 Query: 301 AAGSKGLTIFPEE 313 A ++ Sbjct: 122 AGNDLPTVVYNVN 134 >2ZJ1-A nrPDB Length = 495 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 28/84 (33%), Gaps = 14/84 (16%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 G + G G VG K GA R+ +I+ ++A G ++ Sbjct: 275 GKKVLICGYGDVGKGCAEAMKGQGA-RVSVTEIDPINALQAMMEGFDVVT--------VE 325 Query: 258 EVIIELTKGGVDFALDCAGGSETM 281 E I G D + G + + Sbjct: 326 EAI-----GDADIVVTATGNKDII 344 >1CYD-A nrPDB Length = 244 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 18/44 (40%), Gaps = 1/44 (2%) Query: 198 GSTCAVFGLG-GVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 G V G G G+G V A+GA + NS+ AK Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKE 50 >3CJR-A nrPDB Length = 254 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 33/184 (17%), Positives = 57/184 (30%), Gaps = 15/184 (8%) Query: 155 YTVVSDINLAK---IDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGL 211 + V++ + + I G +T + PG G G G+ Sbjct: 75 FVVLAPWHTWEGAEIPLVIEPGMAFGTGHHETTRLALKALARHLRPGDKVLDLGTGS-GV 133 Query: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFA 271 A+ K G + +G+DI+ +A+A + + PR L ++ L G D Sbjct: 134 LAIAAEKLGGKA--LGVDIDPMVLPQAEANAKRNGVRPRFLEGSLEAA---LPFGPFDLL 188 Query: 272 LDCAGGSETMKAAL----DCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGG 327 + A + AAL G G+ L R + G Sbjct: 189 V--ANLYAELHAALAPRYREALVPGGRALLTGILKDRAPLVREAMAGAGFRPLEEAAEGE 246 Query: 328 WKSV 331 W + Sbjct: 247 WVLL 250 >4J90-A nrPDB Length = 222 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 28/79 (35%), Gaps = 5/79 (6%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 AV GLG G S G ++ +DIN EK + AT + + Sbjct: 7 KQFAVIGLGRFGGSICKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEE---N 61 Query: 259 VIIELTKGGVDFALDCAGG 277 ++ L ++ + G Sbjct: 62 ELLSLGIRNFEYVIVAIGA 80 >4DIB-A nrPDB Length = 345 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 40/129 (31%), Gaps = 19/129 (14%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN--SEKFVKAKALGATD-----CLNPRDL 252 A+ G G +G A I+ I+ + SE + + Sbjct: 6 RVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAFED 65 Query: 253 HKPIQEVIIEL-----------TKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 H + +I L T GV+ ++ G + + A+ AG + Sbjct: 66 HLLVDGKMIRLLNNRDPKELPWTDLGVEVVIEATGKFNSKEKAILHVEAG-AKKVILTAP 124 Query: 302 AGSKGLTIF 310 ++ +TI Sbjct: 125 GKNEDVTIV 133 >3G1U-A nrPDB Length = 437 Score = 33.2 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINS 232 G TC V G G VG +A GA R++ +++ Sbjct: 211 AGKTCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDP 245 >5JE5-A nrPDB Length = 247 Score = 33.2 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 19/149 (12%), Positives = 47/149 (31%), Gaps = 23/149 (15%) Query: 221 GASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTK----GGVDFA----- 271 GA++++G+DI+ + A+ R P++ + ++ G D Sbjct: 63 GAAKVVGVDISEKMIELARE-------ESRKYGDPLEFHVRDVANMEPLGQFDLVNAAWL 115 Query: 272 LDCAGGSETMKAALDCTTA---GWGSCTFIGVAAGSK----GLTIFPEELIIGRTINGTF 324 + A E ++ A G V + ++ R + Sbjct: 116 FNYADSVENLRKMFKVVRASLKPDGKLVAYTVDPDFSLAKGNFAKYGVNVLNERAWGPGY 175 Query: 325 FGGWKSVDSIPKLVTDYKNKKFNLDALVT 353 + V P + Y+ + + ++ + Sbjct: 176 RHDAEFVTDPPSQFSFYRWSRADYESAIA 204 >3EMK-A nrPDB Length = 246 Score = 33.2 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 33/86 (38%), Gaps = 9/86 (10%) Query: 198 GSTCAVFGL-GGVGLSAVMGCKAAGASRIIGI-DINSEKF-VKAKALGATDCLNPRDLHK 254 G V G GG+G + A GA I+G+ EK A LG + P +L Sbjct: 7 GRKALVTGATGGLGEAIARALHAQGA--IVGLHGTREEKLKELAAELGERIFVFPANLSD 64 Query: 255 PIQ----EVIIELTKGGVDFALDCAG 276 E GGVD ++ AG Sbjct: 65 REAVKALGQKAEEEMGGVDILVNNAG 90 >2EKL-A nrPDB Length = 313 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%), Gaps = 2/50 (4%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 G T + G G +G + A G +++ DI + KA+ + A Sbjct: 141 AGKTIGIVGFGRIGTKVGIIANAMGM-KVLAYDILDIR-EKAEKINAKAV 188 >1JWB-B nrPDB Length = 249 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN 231 S + GLGG+G +A +AG + +D + Sbjct: 32 SRVLIVGLGGLGCAASQYLASAGVGNLTLLDFD 64 >2YVG-A nrPDB Length = 408 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 37/131 (28%), Gaps = 5/131 (3%) Query: 167 DDDAN-LERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRI 225 L+ + T A A + P S + G G +GL + AG + Sbjct: 113 PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGV-HV 171 Query: 226 IGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAAL 285 ++ +A D + + + G VD + + + A Sbjct: 172 SLVETQPRLMSRAAPATLADFVARYHAAQGVDLRFERSVTGSVDGVVLL---DDGTRIAA 228 Query: 286 DCTTAGWGSCT 296 D G G Sbjct: 229 DMVVVGIGVLA 239 >1X5E-A nrPDB Length = 126 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 25/75 (33%), Gaps = 2/75 (2%) Query: 83 TNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPAS--DQQLMEDKTSRFTCKG 140 + GD +I YAP C C+ + +L+ + D + RF Sbjct: 18 RELLEGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIINA 77 Query: 141 KPVYHFFGTSTFSQY 155 P + F +Y Sbjct: 78 LPTIYHCKDGEFRRY 92 >3OND-A nrPDB Length = 488 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 177 LLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFV 236 L GC S G + G V G G VG K AGA R+I +I+ + Sbjct: 244 LYGCRHSLPDGLMRATDVMIAGKVAVVAGYGDVGKGCAAALKQAGA-RVIVTEIDPICAL 302 Query: 237 KA 238 +A Sbjct: 303 QA 304 >5VMT-A nrPDB Length = 342 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 30/182 (16%), Positives = 52/182 (28%), Gaps = 22/182 (12%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGI---------------DINSEKFVKAKALGAT 244 A+ G G +G A+ + A + + D +F L Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDD 71 Query: 245 D-CLNPRDLHKPIQEVIIELTKG--GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 +N R++ EL G GVD L+C G A AG I Sbjct: 72 AIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFFTNKTKAEAHIRAG-ARKVVISAP 130 Query: 302 AGSKGLTI---FPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPF 358 G+ T+ ++++ G + + + V + H Sbjct: 131 GGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMAAVLQKEFGVVEGLMTTIHAYTG 190 Query: 359 DK 360 D+ Sbjct: 191 DQ 192 >6IQV-A nrPDB Length = 340 Score = 32.8 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 51/173 (29%), Gaps = 24/173 (13%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGAS----RIIGID--INSEKFVKAKALGATD-------- 245 + G G +G A G ++ I+ + +T Sbjct: 4 KIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVS 63 Query: 246 ------CLNPRDLH---KPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCT 296 +N ++ +P + I + GVDF L+C G T KA Sbjct: 64 ATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGF-YTSKAKSQAHLDAGAKRV 122 Query: 297 FIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLD 349 I AGS TI T + + + ++NK+F + Sbjct: 123 LISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIK 175 >5T5Q-A nrPDB Length = 247 Score = 32.8 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 9/85 (10%) Query: 200 TCAVFGL-GGVGLSAVMGCKAAGASRIIGIDINSEKFV-KAKALG-----ATDCLNPRDL 252 T + G GG+G + A+GA+ ++ D++ E A +LG AT + Sbjct: 11 TLVLTGANGGIGRAIAELFHASGANLVL-TDLDREGLDAFAASLGSPERIATIKADASSA 69 Query: 253 HKPIQEVIIELTK-GGVDFALDCAG 276 + V + + + GG+DF + AG Sbjct: 70 DDAEKTVALAMERFGGIDFLVPSAG 94 >4CUK-A nrPDB Length = 338 Score = 32.8 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 G T V G G +G++A+ K G R++ D A LG Sbjct: 144 GKTAGVIGTGKIGVAALRILKGFGM-RLLAFDPYPS--TAALDLGVEYV 189 >4RS3-A nrPDB Length = 327 Score = 32.4 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 43/123 (34%), Gaps = 25/123 (20%) Query: 209 VGLSAVMGCKAAG--ASRIIGIDINSEKFVKAKA---LG----------------ATDCL 247 +GL A+ K AG I+GID + K+ +G A + Sbjct: 205 MGLGALQALKEAGRTGVPIVGIDGIEDGLNAVKSGDFIGTSLQNGTVELSAGLAVADALV 264 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALDCAGGS--ETMKAALDCTTAGW--GSCTFIGVAAG 303 D+ V+ +TK VD A++ + + ++ T G + G+ Sbjct: 265 KGEDVKTDPVYVMPAITKDNVDVAIEHVVTERQKFLDGLVELTQQNLKTGDIAYEGIPGQ 324 Query: 304 SKG 306 ++ Sbjct: 325 TQP 327 >4COO-A nrPDB Length = 563 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 189 AINNAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 A + + PG T G G+GL+ + ++ ++SEK +ALGA Sbjct: 152 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 211 Query: 247 LNPRDLHKPIQE 258 P + E Sbjct: 212 RTPTNARFDSPE 223 >4GCM-A nrPDB Length = 312 Score = 32.4 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 41/224 (18%), Positives = 64/224 (28%), Gaps = 57/224 (25%) Query: 201 CAVFGLGGVGLSAVMGCKAA--------------------------GASRIIGIDINSEK 234 A+ G G G++A + A G I G D++++ Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKM 68 Query: 235 FVKAKALGATD---------------CLNPRDLHKPIQEVI----IELTKGGVDFALDCA 275 F AK GA +N + + VI E K GV + Sbjct: 69 FEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELG 128 Query: 276 GGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIP 335 G + A D IG + F + TI + Sbjct: 129 GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIV-----HRRDELRAQ 183 Query: 336 KLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILI 379 +++ D K +D + +HTL I+E GK L Sbjct: 184 RILQDRAFKNDKIDFIWSHTLK--SINE-----KDGKVGSVTLT 220 >1M54-A nrPDB Length = 363 Score = 32.4 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 189 AINNAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 A + + PG T G G+GL+ + ++ ++SEK +ALGA Sbjct: 87 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 146 Query: 247 LNPRDLHKPIQE 258 P + E Sbjct: 147 RTPTNARFDSPE 158 >6ACF-A nrPDB Length = 367 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAG--ASRIIGIDINSEKFVKA-KALGATDCLNPRDL 252 G AV G VG A C+ +++I DIN E +A + GA ++P D+ Sbjct: 173 GKVVAVQG---VGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAK-AVDPNDI 226 >5AOV-A nrPDB Length = 336 Score = 32.4 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 27/78 (34%), Gaps = 10/78 (12%) Query: 185 GYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT 244 + G T + G G +G + K G + I + K K LGA Sbjct: 137 AWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAK--GFNMRILYYSRTRKSQAEKELGAE 194 Query: 245 DCLNPRDLHKPIQEVIIE 262 +P++EV+ E Sbjct: 195 Y--------RPLEEVLKE 204 >5MMS-A nrPDB Length = 408 Score = 32.4 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 189 AINNAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 A + + PG T G G+GL+ + ++ ++SEK +ALGA Sbjct: 130 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 189 Query: 247 LNPRDLHKPIQE 258 P + E Sbjct: 190 RTPTNARFDSPE 201 >2AS0-A nrPDB Length = 396 Score = 32.4 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 17/48 (35%), Gaps = 6/48 (12%) Query: 195 VTPGSTCA--VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 V PG GG + AGA +IGID + AK Sbjct: 215 VQPGDRVLDVFTYTGGF----AIHAAIAGADEVIGIDKSPRAIETAKE 258 >3GRP-A nrPDB Length = 266 Score = 32.4 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 9/86 (10%) Query: 198 GSTCAVFGL-GGVGLSAVMGCKAAGASRIIGI-DINSEKF-VKAKALGATDCLNPRDL-- 252 G V G GG+G + A GA I+G+ +K A LG + +L Sbjct: 27 GRKALVTGATGGIGEAIARCFHAQGA--IVGLHGTREDKLKEIAADLGKDVFVFSANLSD 84 Query: 253 HKPIQEV--IIELTKGGVDFALDCAG 276 K I+++ + E G+D ++ AG Sbjct: 85 RKSIKQLAEVAEREMEGIDILVNNAG 110 >4XGI-A nrPDB Length = 436 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 19/48 (39%) Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGID 229 F G AA G+ AV G G VG A + AGA I D Sbjct: 215 FVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQD 262 >5TQV-A nrPDB Length = 233 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 28/80 (35%), Gaps = 2/80 (2%) Query: 199 STCAVFGLG-GVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 T + G G+G V + G +I + +ALGA + I Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDG-WNVIATARDDASLAALRALGAHAHALDITQPEQIA 68 Query: 258 EVIIELTKGGVDFALDCAGG 277 + +L +D A+ +G Sbjct: 69 ALGWKLDGERLDVAVVVSGV 88 >5ITV-A nrPDB Length = 255 Score = 32.0 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 50/149 (33%), Gaps = 16/149 (10%) Query: 199 STCAVFG-LGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA--KA------LGATDCLNP 249 T + G G+G +AV + ++ DI+ + K TD + Sbjct: 8 KTVLITGGASGIGYAAVQ-AFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDE 66 Query: 250 RDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFI---GVAAGSKG 306 ++ + T GG+D ++ AG E + + + W + G+ SK Sbjct: 67 AACQHAVESAVH--TFGGLDVLINNAG-IEIVAPIHEMELSDWNKVLQVNLTGMFLMSKH 123 Query: 307 LTIFPEELIIGRTINGTFFGGWKSVDSIP 335 G IN GG + IP Sbjct: 124 ALKHMLAAGKGNIINTCSVGGLVAWPDIP 152 >3JTJ-A nrPDB Length = 253 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 39/126 (30%), Gaps = 8/126 (6%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLH--- 253 PG A + + + A+GA R+I + + +A G CL D Sbjct: 20 PGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGT 79 Query: 254 KPIQEVIIELTKGGVDFALDCAGG-----SETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 + + EVI D ++ G ++ D A + V S Sbjct: 80 ERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEA 139 Query: 309 IFPEEL 314 P + Sbjct: 140 FNPNAV 145 >1XDW-A nrPDB Length = 331 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 16/35 (45%), Gaps = 1/35 (2%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK 234 T V GLG +G A GA +IG D+ K Sbjct: 148 TVGVVGLGRIGRVAAQIFHGMGA-TVIGEDVFEIK 181 >3N58-A nrPDB Length = 464 Score = 32.0 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 23/161 (14%), Positives = 44/161 (27%), Gaps = 24/161 (14%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 G V G G VG + AGA R+ +++ ++A G Sbjct: 246 AGKVAVVCGYGDVGKGSAQSLAGAGA-RVKVTEVDPICALQAAMDGFEVV-----TLDDA 299 Query: 257 QEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELII 316 D + G + + +D C + + ++ Sbjct: 300 AST--------ADIVVTTTGNKDVI--TIDHMRKMKDMCIVGNIGHFDNEI-----QVAA 344 Query: 317 GRTINGTFFGGWKSVDSIP---KLVTDYKNKKFNLDALVTH 354 R + T + P +L+ + + NL H Sbjct: 345 LRNLKWTNVKPQVDLIEFPDGKRLILLSEGRLLNLGNATGH 385 >4PZE-A nrPDB Length = 284 Score = 32.0 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 43/131 (32%), Gaps = 15/131 (11%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGA---TDCLNPRDLHKPI 256 T + G G +G C G + ++ +DI+ K A A + L + Sbjct: 5 TVGIVGAGTMGNGIAQACAVVGLN-VVMVDISDAAVQKGVATVASSLDRLIKKEKLTEAD 63 Query: 257 QEVIIELTKGG--------VDFALDCAGGSETMKAALDCTTAGWGSCT-FIGVAAGSKGL 307 + + KG D ++ A +E + G + +A+ + + Sbjct: 64 KASALARIKGSTSYDDLKATDIVIEAA--TENYDLKVKILKQIDGIVGENVIIASNTSSI 121 Query: 308 TIFPEELIIGR 318 +I + R Sbjct: 122 SITKLAAVTSR 132 >3HWR-A nrPDB Length = 318 Score = 32.0 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 30/102 (29%), Gaps = 5/102 (4%) Query: 198 GSTCAVFGLGGVGL-SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 G A+ G G VG M +A +I I + +A G D + Sbjct: 19 GMKVAIMGAGAVGCYYGGMLARA--GHEVILIAR-PQHVQAIEATGLRLETQSFDEQVKV 75 Query: 257 QEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFI 298 G D L C ++T AAL + Sbjct: 76 SASSDPSAVQGADLVLFCVKSTDTQSAAL-AMKPALAKSALV 116 >1B26-A nrPDB Length = 416 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 37/218 (16%), Positives = 66/218 (30%), Gaps = 38/218 (17%) Query: 181 GFSTGYGAAINNAKVTPGS-TCAVFGLGGVG-LSAVMGCKAAGASRIIGIDIN------- 231 G G A++ + P T AV G G VG +A++ + G+ + D Sbjct: 192 GVKVCAGLAMDVLGIDPKKATVAVQGFGNVGQFAALLISQELGSKVVAVSDSRGGIYNPE 251 Query: 232 ----SEKFVKAKALGA-------TDCLNPRDLHKPIQEVIIELTKGGVD----------F 270 E K G N L + ++ +G + Sbjct: 252 GFDVEELIRYKKEHGTVVTYPKGERITNEELLELDVDILVPAALEGAIHAGNAERIKAKA 311 Query: 271 ALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKS 330 ++ A G T +A D + G + A + G+T+ E + + Sbjct: 312 VVEGANGPTTPEA--DEILSRRGILVVPDILANAGGVTVSYFEWV------QDLQSFFWD 363 Query: 331 VDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLM 368 +D + + FN V D + A+ L Sbjct: 364 LDQVRNALEKMMKGAFNDVMKVKEKYNVDMRTAAYILA 401 >1VE9-A nrPDB Length = 347 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 15/45 (33%) Query: 257 QEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 E E+ +GG D ++C G + G G + Sbjct: 164 VESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAP 208 >1WG8-A nrPDB Length = 285 Score = 31.6 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 7/89 (7%) Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 Y A++ V PG LGG G + + + R+IG+D + E +AK L Sbjct: 7 VPVLYQEALDLLAVRPGGVYVDATLGGAGHARGILER---GGRVIGLDQDPEAVARAKGL 63 Query: 242 ---GATDCL-NPRDLHKPIQEVIIELTKG 266 G T N R L + + + +E G Sbjct: 64 HLPGLTVVQGNFRHLKRHLAALGVERVDG 92 >5EES-A nrPDB Length = 247 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 17/135 (12%), Positives = 37/135 (27%), Gaps = 15/135 (11%) Query: 212 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFA 271 V+G K I+ S+ +G D + L G + Sbjct: 4 VGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDD-------------DLSLLVDNGAEVV 50 Query: 272 LDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSV 331 +D + L+ G +G + + G+ G ++ Sbjct: 51 VDFT-TPNAVMGNLEFC-INNGISAVVGTTGFDDARLEQVRDWLEGKDNVGVLIAPNFAI 108 Query: 332 DSIPKLVTDYKNKKF 346 ++ +V + +F Sbjct: 109 SAVLTMVFSKQAARF 123 >4FS8-A nrPDB Length = 383 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 46/255 (18%), Positives = 79/255 (30%), Gaps = 30/255 (11%) Query: 113 CGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANL 172 C + D + + K TS V + + + D A+ Sbjct: 5 CASGCQKSKNGGSTPSIRDHVADYYGKTLQSSADLKTSACKLAAAVPESHRKILADIADE 64 Query: 173 ERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA-SRIIGIDIN 231 GCG + ++ G+T G G G + K G ++IG+D+ Sbjct: 65 VLEKFYGCGSTLPADGSLE------GATVLDLGCGT-GRDVYLASKLVGEHGKVIGVDML 117 Query: 232 SEKFVKAKA---------LGATDCLNPRDLHKPIQEVIIELTKGGVDFALD-----CAGG 277 + A+ G+ N R L I+ + +G D ++D C Sbjct: 118 DNQLEVARKYVEYHAEKFFGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIVISNCVCN 177 Query: 278 SETMKAALDC----TTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDS 333 T K AL G F V A + ++ I + G GG ++ Sbjct: 178 LSTNKLALFKEIHRVLRDGGELYFSDVYADRRLSEAAQQDPI----LYGECLGGALYLED 233 Query: 334 IPKLVTDYKNKKFNL 348 +LV + + L Sbjct: 234 FRRLVAEAGFRDVRL 248 >5JJC-A nrPDB Length = 342 Score = 31.6 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 27/92 (29%), Gaps = 12/92 (13%) Query: 189 AINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGI--DINSEKFVKAKALGATDC 246 A + PG G G+ M KA G I I + EK + LGA Sbjct: 53 AEKRGLLRPGGVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELI 112 Query: 247 ----------LNPRDLHKPIQEVIIELTKGGV 268 N L + E + + G Sbjct: 113 EVPAAPYRNPNNAVRLSGRLAEQLAKTEPNGA 144 >3NJ4-A nrPDB Length = 435 Score = 31.6 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 6/77 (7%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 G V G G VG + GA R+I +I+ ++A A + + + Sbjct: 215 AGKVAVVAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQA----AMEGYEVTTMDEAC 269 Query: 257 QE-VIIELTKGGVDFAL 272 QE I T G +D L Sbjct: 270 QEGNIFVTTTGCIDIIL 286 >3FBT-A nrPDB Length = 282 Score = 31.6 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 47/144 (32%), Gaps = 20/144 (13%) Query: 185 GYGAAINNAKVT-PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK--------- 234 G+G ++ +V + C V G GG + + K A I + N EK Sbjct: 108 GFGKMLSKFRVEIKNNICVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEKTSEIYGEFK 167 Query: 235 ---FVKAKALGATDCLN-------PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAA 284 + + L +N P++ P+ + ++ VD + A Sbjct: 168 VISYDELSNLKGDVIINCTPKGMYPKEGESPVDKEVVAKFSSAVDLIYNPVETLFLKYAR 227 Query: 285 LDCTTAGWGSCTFIGVAAGSKGLT 308 A G + AA S+ + Sbjct: 228 ESGVKAVNGLYMLVSQAAASEEIW 251 >1W1U-A nrPDB Length = 557 Score = 31.6 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 30/92 (32%), Gaps = 5/92 (5%) Query: 191 NNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR 250 + G GLGG+G + + AGA + I+ + T ++ + Sbjct: 160 HYGGSLKGKWVLTAGLGGMGGAQPLAATLAGACSL-NIESQQSRIDFRLE---TRYVDEQ 215 Query: 251 DLH-KPIQEVIIELTKGGVDFALDCAGGSETM 281 I + T G ++ G + + Sbjct: 216 ATDLDDALVRIAKYTAEGKAISIALHGNAAEI 247 >3BKX-A nrPDB Length = 275 Score = 31.6 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 183 STGYGAAINNA-KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKAL 241 T + AI A +V PG G G LSAV+ + + + GIDI S + L Sbjct: 28 QTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTL 87 Query: 242 G 242 G Sbjct: 88 G 88 >4K28-A nrPDB Length = 269 Score = 31.6 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 20/48 (41%) Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK 234 GAA + G V G GGVG + AG + I D ++ + Sbjct: 114 GAAHKHGFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTAR 161 >4MIE-A nrPDB Length = 351 Score = 31.2 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 29/78 (37%), Gaps = 6/78 (7%) Query: 200 TCAVFGLGGVGLSAV--MGCKAAGASRIIGIDINSEKFVKA-KALGATDCLNPRD---LH 253 V G G +G + + + GA + DI+ E A + + P D L Sbjct: 16 KVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAKVYPDDTSLLQ 75 Query: 254 KPIQEVIIELTKGGVDFA 271 P + + ++ GG A Sbjct: 76 DPDIDAVFVVSFGGAHEA 93 >4JZB-A nrPDB Length = 362 Score = 31.2 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 16/160 (10%), Positives = 52/160 (32%), Gaps = 10/160 (6%) Query: 41 IIATSLCHTDATVIDSKFEGLAFPVIVGHEAAGIVESIGPGVTN---------VKPGDKV 91 + T H V + + P+++G +G +E + T+ + D V Sbjct: 193 VEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDV 252 Query: 92 IPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTST 151 + + P + K C ++ + + + + + + Sbjct: 253 MDCFTPPEKLGKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQ-L 311 Query: 152 FSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAIN 191 +++ +++ + A +E++ + + A++ Sbjct: 312 YTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVK 351 >1QO8-A nrPDB Length = 566 Score = 31.2 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINS 232 V G G G +A + K AGA+ +I +D Sbjct: 124 VLVVGAGSAGFNASLAAKKAGAN-VILVDKAP 154 >2WWR-A nrPDB Length = 330 Score = 31.2 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 24/79 (30%), Gaps = 1/79 (1%) Query: 172 LERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN 231 E + + G T + ST + GLG +G + K G R + Sbjct: 129 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 188 Query: 232 SEKFVKAKALGATDCLNPR 250 + +A A P Sbjct: 189 P-RPEEAAEFQAEFVSTPE 206 >1ZOD-A nrPDB Length = 433 Score = 31.2 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 16/116 (13%) Query: 255 PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL 314 + + +T G+D AL + G+E+ +AA+ G +G A G+T Sbjct: 89 DLATRLANITPPGLDRALLLSTGAESNEAAIRMAKLVTGKYEIVGFAQSWHGMT------ 142 Query: 315 IIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQ 370 G + T+ G K V F + A T+ F++ + A+D + + Sbjct: 143 --GAAASATYSAGRKG-------VGPAAVGSFAIPAPFTYRPRFER-NGAYDYLAE 188 >4IZO-A nrPDB Length = 419 Score = 31.2 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 195 VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINS 232 + PG+ + G G +G +A G R+ +D + Sbjct: 32 ILPGAWLGMVGGGQLGRMFCFAAQAMG-YRVAVLDPDP 68 >2EEZ-A nrPDB Length = 369 Score = 31.2 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 67/200 (33%), Gaps = 41/200 (20%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFV-------------KAKA------ 240 + + G G VG +A GA ++ +D+N ++ A Sbjct: 168 SVVILGGGTVGTNAAKIALGMGA-QVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKS 226 Query: 241 -------LGATDCLNPRDLHKPIQEVIIELTKGG--VDFALDCAGGSETMKAALDC--TT 289 +GA + ++++ + +G VD A+D G ET++ T Sbjct: 227 VQHADLLIGAVLVPGAKAPKLVTRDMLSLMKEGAVIVDVAVDQGGCVETIRPTTHAEPTY 286 Query: 290 AGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLD 349 G + GVA + + +T+ K +D++ + L Sbjct: 287 VVDGVVHY-GVANMPGAVPRTSTFALTNQTLPYVLKLAEKGLDALLEDAAL-------LK 338 Query: 350 ALVTHTLPFDK--ISEAFDL 367 L TH ++EAF L Sbjct: 339 GLNTHKGRLTHPGVAEAFGL 358 >2UVD-A nrPDB Length = 246 Score = 31.2 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 48/143 (33%), Gaps = 16/143 (11%) Query: 210 GLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVD 269 G A++ + G R I ID AK GA +N + EV+ E+ K G D Sbjct: 4 GKVALVTGASRGIGRAIAID-------LAKQ-GANVVVNYAGNEQKANEVVDEIKKLGSD 55 Query: 270 FA---LDCAGGSET---MKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGT 323 D A + +K +D G L + +E IN Sbjct: 56 AIAVRADVANAEDVTNMVKQTVDV--FGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTN 113 Query: 324 FFGGWKSVDSIPKLVTDYKNKKF 346 G + ++ + + ++ + Sbjct: 114 LKGVFLCTKAVSRFMMRQRHGRI 136 >4Q1T-A nrPDB Length = 376 Score = 31.2 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 40/122 (32%), Gaps = 11/122 (9%) Query: 204 FGLGGV--GLSAVMGCKAAGASRIIGIDINSE---KFVKAKALGATDCLNPRDLHKPIQE 258 G GG+ + A +GA+ +I + + +A+G + Q Sbjct: 217 IGRGGMLTKILAAKRAAHSGANTVIASGRERDVLLRLASGEAIGTQLIARTARMAARKQW 276 Query: 259 VIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGR 318 + L G +D AG + + A G GV A + + + GR Sbjct: 277 MADHLQVRG-HVVID-AGAVDKLTAGGKSLLP-IGVVAVQGVFARGEVIACVND---AGR 330 Query: 319 TI 320 + Sbjct: 331 EV 332 >3WGE-A nrPDB Length = 113 Score = 30.8 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 22/70 (31%), Gaps = 3/70 (4%) Query: 84 NVKPGDKVIPLYAPLCRKCKFCLSPLTNL---CGKISNLKSPASDQQLMEDKTSRFTCKG 140 +V GD I +AP C CK L +K D + S +G Sbjct: 17 HVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRG 76 Query: 141 KPVYHFFGTS 150 P +F Sbjct: 77 YPTLLWFRDG 86 >6J0Z-C nrPDB Length = 491 Score = 30.8 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 1/44 (2%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 S V G G GL + AG S ++ +D +E +++ALG Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVS-VVVLDKLAEPIKESRALG 48 >3NT2-A nrPDB Length = 344 Score = 30.8 bits (68), Expect = 0.91, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 30/96 (31%), Gaps = 15/96 (15%) Query: 200 TCAVFGLGGVG--LSAVMGCKAAGASRIIGIDINSEKFVKAKA---LGATDCLNPRDLHK 254 V G G +G + K +GA + D+N E K L AT N L Sbjct: 4 RIGVIGTGAIGKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQYQLNATVYPNDDSL-- 61 Query: 255 PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTA 290 L VD L + G + L A Sbjct: 62 --------LADENVDAVLVTSWGPAHESSVLKAIKA 89 >4LRT-B nrPDB Length = 323 Score = 30.8 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 23/134 (17%), Positives = 42/134 (31%), Gaps = 12/134 (8%) Query: 202 AVFGLGGVG---LSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 A+ G G +G L + + ++G+D SE +A+ LG + + E Sbjct: 27 AIVGPGNIGTDLLIKLQRSEHIEVRYMVGVDPASEGLARARKLGVEA---SAEGVDWLLE 83 Query: 259 VIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGS-KGLTIFPEELIIG 317 D + + A AG + A G + E + Sbjct: 84 Q-----DELPDLVFEATSAKAHLANAPRYAEAGITAIDLTPAAVGPLVCPPVNLTEHLDA 138 Query: 318 RTINGTFFGGWKSV 331 +N GG ++ Sbjct: 139 PNVNMITCGGQATI 152 >1GPJ-A nrPDB Length = 404 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 24/64 (37%), Gaps = 5/64 (7%) Query: 188 AAINNAKVTPGS----TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK-FVKAKALG 242 AA+ A+ GS T V G G +G + G ++ + E+ A+ LG Sbjct: 153 AAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLG 212 Query: 243 ATDC 246 Sbjct: 213 GEAV 216 >5UJU-A nrPDB Length = 576 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 28/98 (28%), Gaps = 4/98 (4%) Query: 225 IIGIDINSEKFVKAKALGATD----CLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSET 280 +I D ++ A + A I +GGV +++ GG Sbjct: 463 VIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFV 522 Query: 281 MKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGR 318 ++A G G+ A ++ R Sbjct: 523 NQSAAFSDFHGTGANPAANAALADAAFVANRFRVVQSR 560 >5ZBK-A nrPDB Length = 203 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 33/146 (22%), Positives = 52/146 (35%), Gaps = 14/146 (9%) Query: 178 LGCGFSTGYGAAINNAKVTPGSTCA------VFGLGGVGLS-AVMGCKAAGASRIIGIDI 230 + CG S G A V G A V+G G VGL V A +IG I Sbjct: 8 VFCGASPGASPVYQEAAVALGRHLAERGLTLVYGGGAVGLMGTVADAALAAGGEVIG--I 65 Query: 231 NSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTA 290 + +A +G L ++ + + + D + GG T++A + T Sbjct: 66 IPQSLQEA-EIG-HKGLTRLEVVDGMHARKARMAE-LADAFIALPGGLGTLEALFEVWT- 121 Query: 291 GWGSCTFIGVAAGSKGLTIFPEELII 316 WG + G + F + L+ Sbjct: 122 -WGQLGYHAKPLGLLEVNGFYDPLLT 146 >3TNL-A nrPDB Length = 315 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 24/69 (34%), Gaps = 3/69 (4%) Query: 184 TGYGAAINNAKVTP-GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 TGY A+ A G + G GG + + G I + + + A+ Sbjct: 139 TGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFNRKDDFYANAEK-- 196 Query: 243 ATDCLNPRD 251 + +N + Sbjct: 197 TVEKINSKT 205 >1UIR-A nrPDB Length = 314 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 50/153 (32%), Gaps = 19/153 (12%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA------LGATDCLNPRD- 251 + G GG G + K + + +DI+ E AK GA D +PR Sbjct: 79 KRVLIVG-GGEGATLREVLKHPTVEKAVMVDIDGELVEVAKRHMPEWHQGAFD--DPRAV 135 Query: 252 LHKPIQEVIIELTKGGVDFAL----DCAG--GSETMKAALD---CTTAGWGSCTFIGVAA 302 L +E T+ D + D G + ++ A +G+ Sbjct: 136 LVIDDARAYLERTEERYDVVIIDLTDPVGEDNPARLLYTVEFYRLVKAHLNPGGVMGMQT 195 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIP 335 G LT ++ RT+ F + IP Sbjct: 196 GMILLTHHRVHPVVHRTVREAFRYVRSYKNHIP 228 >4KIC-A nrPDB Length = 357 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 37/196 (18%), Positives = 64/196 (32%), Gaps = 26/196 (13%) Query: 185 GYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA-KALGA 243 + AA++ TP +T A G G G + + R +G+DI A K + A Sbjct: 167 AFWAAVDGLGYTP-TTVADLGSGS-GERLIQIARRFPGVRGLGVDIADGAIAMAEKEVAA 224 Query: 244 ----TDCLNPRDLHKPIQEVIIELTKGGVDFAL------------DCAGGSETMKAALDC 287 R + I +V VD +C ++AA Sbjct: 225 KGFGDQISFVRGDARTIDQVSARGEFAEVDLLTCFMMGHDFWPRENCVQTLRKLRAAFPN 284 Query: 288 TTA---GWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNK 344 G + T +G+ + L +F G + G + D + + K Sbjct: 285 VRRFLLGDATRT-VGIP--DRELPVFTLGFEFGHDMMGVYLPTLDEWDGVFEEGGWRCVK 341 Query: 345 KFNLDAL-VTHTLPFD 359 K +D+L V+ + Sbjct: 342 KHAIDSLSVSVVFELE 357 >2NVU-B nrPDB Length = 805 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 29/80 (36%), Gaps = 6/80 (7%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEV 259 V G GG+G + +G +I ID+++ L P+D+ +P EV Sbjct: 413 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVS---NLNRQFLFRPKDIGRPKAEV 469 Query: 260 IIELTKGGVDFALDCAGGSE 279 E D +C Sbjct: 470 AAEFLN---DRVPNCNVVPH 486 >1YOV-B nrPDB Length = 444 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 29/80 (36%), Gaps = 6/80 (7%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEV 259 V G GG+G + +G +I ID+++ L P+D+ +P EV Sbjct: 52 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVS---NLNRQFLFRPKDIGRPKAEV 108 Query: 260 IIELTKGGVDFALDCAGGSE 279 E D +C Sbjct: 109 AAEFLN---DRVPNCNVVPH 125 >1YPF-A nrPDB Length = 336 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 24/67 (35%), Gaps = 7/67 (10%) Query: 187 GAAINNAKVTPGSTCAV-----FGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK-- 239 GA + PG C FG GG L+A+ C A + II AK Sbjct: 170 GADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTNGDVAKSI 229 Query: 240 ALGATDC 246 GAT Sbjct: 230 RFGATMV 236 >1T5A-A nrPDB Length = 567 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 42/287 (14%), Positives = 78/287 (27%), Gaps = 47/287 (16%) Query: 49 TDATVIDSKFEGLAFPV-----IVGHEAA-----------GIVESIGPGVTNVKPGDKVI 92 +D + + I HE GI+ + G + P +KV Sbjct: 285 SDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEI-PAEKVF 343 Query: 93 PLYAPLCRKCKFCLSPLTNLCG--KISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTS 150 + +C + +C + ++ + + G G + Sbjct: 344 LAQKMMIGRCN--RAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGET 401 Query: 151 TFSQY-----------TVVSDINLAKIDDDANLERVCLLGCGFS--TGYGAAINNAKVTP 197 Y ++ + + L R+ + + T GA + K Sbjct: 402 AKGDYPLEAVRMQNLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCS 461 Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 G+ + G SA + + II + N A+ + P P+Q Sbjct: 462 GAIIVLTKSGR---SAHQVARYRPRAPIIAVTRNP---QTARQAHLYRGIFPVLCKDPVQ 515 Query: 258 EVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGS 304 E E V+FA++ A G G GS Sbjct: 516 EAWAEDVDLRVNFAMNVG-------KARGFFKKGDVVIVLTGWRPGS 555 >4MOP-A nrPDB Length = 633 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 21/60 (35%), Gaps = 4/60 (6%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI 260 + G G +G + AG ++ DI +GA N + K I + + Sbjct: 49 VVIVGSGPIGCTYARELVGAG-YKVAMFDIGE--IDSGLKIGA-HKKNTVEYQKNIDKFV 104 >4EJ0-A nrPDB Length = 342 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 30/85 (35%), Gaps = 3/85 (3%) Query: 200 TCAVFGLGG-VGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 T V G G +G + V G +RII +D N + K K L ++ E Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVD-NLTRADKFKNL-VDCEIDDYLDKTEFVE 71 Query: 259 VIIELTKGGVDFALDCAGGSETMKA 283 G V S+TM+ Sbjct: 72 RFARGDFGKVRAVFHEGACSDTMET 96 >6BQ5-A nrPDB Length = 331 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 24/63 (38%), Gaps = 4/63 (6%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 + G GG G +A + +++ DI+ E K+ +N H E Sbjct: 103 KNVFIMG-GGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSY---LVVNKEAFHDSRLE 158 Query: 259 VII 261 V+I Sbjct: 159 VVI 161 >3HDH-A nrPDB Length = 302 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 15/42 (35%), Gaps = 1/42 (2%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 V G G +G A G ++ +D + K+K Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >4YRY-B nrPDB Length = 468 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%) Query: 195 VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 + G AV G G + A GA ++ + +E+ + A+ Sbjct: 276 IRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARR 321 >2XF8-A nrPDB Length = 338 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 29/103 (28%), Gaps = 29/103 (28%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGA-SRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 A+ G G +G + V +G + I + IN A A G L H Sbjct: 3 RVAINGFGRIGRNVVRALYESGRRAEITVVAIN----ELADAAGMAHLLKYDTSHGRFAW 58 Query: 259 VIIELTKG------------------------GVDFALDCAGG 277 + + GVD LDC G Sbjct: 59 EVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV 101 >1LSS-A nrPDB Length = 140 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 33/98 (33%) Query: 168 DDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIG 227 A+ E L+ G T + AV G V L + + K+ G ++ I Sbjct: 41 KKASAEIDALVINGDCTKIKTLEDAGIEDADMYIAVTGKEEVNLMSSLLAKSYGINKTIA 100 Query: 228 IDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTK 265 E + LG ++P + E +IE Sbjct: 101 RISEIEYKDVFERLGVDVVVSPELIAANYIEKLIERPG 138 >3AOE-A nrPDB Length = 424 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 18/48 (37%) Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGID 229 F T AA G+ A+ G G VG +A GA + D Sbjct: 203 FITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQD 250 >2RIR-A nrPDB Length = 300 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 30/188 (15%), Positives = 59/188 (31%), Gaps = 5/188 (2%) Query: 142 PVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTC 201 ++ + + L K+ + ++ + T A + GS Sbjct: 101 VIFSGISNAYLENIAAQAKRKLVKLFERDDIAIYNSIPTVEGTIMLAIQHTDYTIHGSQV 160 Query: 202 AVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT--DCLNPRDLHKPIQEV 259 AV GLG G++ A GA+ +G +S + +G ++ K I Sbjct: 161 AVLGLGRTGMTIARTFAALGANVKVGA-RSSAHLARITEMGLVPFHTDELKEHVKDIDIC 219 Query: 260 IIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRT 319 I + ++ + + +T+ LD + G+ G K L I+ Sbjct: 220 INTIPSMILNQTVLSSMTPKTLI--LDLASRPGGTDFKYAEKQGIKALLAPGLPGIVAPK 277 Query: 320 INGTFFGG 327 G Sbjct: 278 TAGQILAN 285 >3PPI-A nrPDB Length = 281 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 33/102 (32%), Gaps = 3/102 (2%) Query: 179 GCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA 238 + G G+ + + S G GG+G + V A G +I + A Sbjct: 12 LEAQTQGPGSMVTIKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALA 71 Query: 239 KALG--ATDCLNPRDLHKPIQEVIIELTK-GGVDFALDCAGG 277 LG A + I + G + +A+ GG Sbjct: 72 DELGNRAEFVSTNVTSEDSVLAAIEAANQLGRLRYAVVAHGG 113 >6APH-A nrPDB Length = 445 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 15/45 (33%), Gaps = 2/45 (4%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEK-FVKAKA 240 G V G G VG + AG S + +I+ A Sbjct: 225 AGKRVVVCGFGDVGKGTAASFRGAG-SIVTVTEIDPICALQAAME 268 >3H9U-A nrPDB Length = 436 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 17/45 (37%), Gaps = 2/45 (4%) Query: 197 PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINS-EKFVKAKA 240 G T V G G VG + GA R++ +++ A Sbjct: 210 AGKTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAME 253 >1F14-A nrPDB Length = 310 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 15/42 (35%), Gaps = 1/42 (2%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 V G G +G A G ++ +D + K+K Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >3HM2-A nrPDB Length = 178 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 34/107 (31%), Gaps = 11/107 (10%) Query: 207 GGVGLSAVMGCKAAGASRIIGIDINSEKFVK----AKALGATDCLNPRDLHKPIQEVIIE 262 GG G A+ ++ + + +I+ E+ + A LG +D + + + + + Sbjct: 34 GGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVSDRIAVQQGAPRAFDDVPD 93 Query: 263 LTKGGVDFALDCAG--GSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 D G AA G V S+ + Sbjct: 94 ----NPDVIFIGGGLTAPGVFAAA-WKRLPVGGRLVANAVTVESEQM 135 >6ABI-A nrPDB Length = 358 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 16/44 (36%) Query: 223 SRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG 266 ++II DI K GA L + E LTKG Sbjct: 27 TKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLTKG 70 >3DC2-A nrPDB Length = 529 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 12/28 (42%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRI 225 G T V GLG +G A GA + Sbjct: 142 GKTVGVVGLGRIGQLVAQRIAAFGAYVV 169 >6GME-A nrPDB Length = 201 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Query: 228 IDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGS 278 +D+ E A +LGAT +N + + E++ + FA D Sbjct: 62 VDVREEGKENAFSLGATLWINSEEFED-LDEIVARYVQPMASFARDLLNHK 111 >4AEC-A nrPDB Length = 430 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 48/159 (30%), Gaps = 43/159 (27%) Query: 189 AINNAKVTPGSTCAV---FGLGGVGLSAVMGCKAAGASRIIGI---DINSEKFVKAKALG 242 A ++PG + V G G+GL+ + + R+I ++ E+ V KA G Sbjct: 165 AEQKGFISPGKSVLVEPTSGNTGIGLAFIAASR---GYRLILTMPASMSMERRVLLKAFG 221 Query: 243 ATDCL----------------------------------NPRDLHKPIQEVIIELTKGGV 268 A L NP+ ++ I + TKG V Sbjct: 222 AELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKV 281 Query: 269 DFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGL 307 D + G T+ IGV + Sbjct: 282 DIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDI 320 >4XRR-A nrPDB Length = 456 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 25/95 (26%), Gaps = 26/95 (27%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFV----------------KAKALGA 243 + G G VG + GA ++ +D + + L A Sbjct: 17 KVVIAGAGYVGTCLAVTLAGRGA-EVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLAA 75 Query: 244 TDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGS 278 T L + P+ G D + G Sbjct: 76 TGRLTASTSYDPV---------GAADVVIVTVGTP 101 >2LDB-A nrPDB Length = 317 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 50/154 (32%), Gaps = 26/154 (16%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAG-ASRIIGIDINSEKF---VKAKALGATDCLNPRDLH 253 G+ V G G VG S V G A I+ ID N K G P D+ Sbjct: 6 GARVVVIGAGFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPKPVDIW 65 Query: 254 KPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEE 313 + + D + CAG ++ G + K + IF Sbjct: 66 HGDYDDCRD-----ADLVVICAGANQ---------KPGETRLDLV-----DKNIAIFRSI 106 Query: 314 LIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFN 347 + ++ + F G V + P + Y KF+ Sbjct: 107 V---ESVMASGFQGLFLVATNPVDILTYATWKFS 137 >3ZZN-A nrPDB Length = 310 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 20/57 (35%), Gaps = 3/57 (5%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPI 256 + G G VG + G +R + + K +A A D L+ P+ Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQA---HAEDILHATPFAHPV 55 >4F86-A nrPDB Length = 320 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 24/64 (37%), Gaps = 6/64 (9%) Query: 191 NNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVK----AKALGATDC 246 + V PG T G G G + ++ G+ +++ + A+ LG D Sbjct: 119 HLGPVGPGDTLVDAGCGRGGSMVM--AHQRFGCKVEGVTLSAAQAEFGNRRARELGIDDH 176 Query: 247 LNPR 250 + R Sbjct: 177 VRSR 180 >4C12-A nrPDB Length = 501 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 47/132 (35%), Gaps = 4/132 (3%) Query: 246 CLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTA--GWGSCTFIGVAA 302 + + +P++ + L +D +D A ++ M +D +G+A Sbjct: 322 IIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQPFVKQKLIFLVGMA- 380 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 G + LT PE + + F + PK++T K + + I Sbjct: 381 GERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAELAKGATHQNYIEFDDRAEGIK 440 Query: 363 EAFDLMNQGKSV 374 A D+ G +V Sbjct: 441 HAIDIAEPGDTV 452 >4P4L-A nrPDB Length = 277 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 42/121 (34%), Gaps = 7/121 (5%) Query: 202 AVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCL-------NPRDLHK 254 V G GG +AV+G G + I + NS+K + LG + + L Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATRFCAFDSGGLAD 180 Query: 255 PIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL 314 + + ++ + A AG + LD W + V + + + L Sbjct: 181 AVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGRVISGLQML 240 Query: 315 I 315 + Sbjct: 241 L 241 >5NMX-A nrPDB Length = 425 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 10/22 (45%), Positives = 11/22 (50%) Query: 200 TCAVFGLGGVGLSAVMGCKAAG 221 AV G G GL+A K AG Sbjct: 3 RVAVLGAGPSGLTAARYLKQAG 24 >3GDF-A nrPDB Length = 267 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 49/145 (33%), Gaps = 16/145 (11%) Query: 198 GSTCAVFGLG---GVGLSAVMGCKAAGASR-IIGIDINSEKFVKAKALGATDCLNPR--- 250 G V G G+G+ A GC GA+ I K L T + + Sbjct: 20 GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYK 79 Query: 251 ---DLHKPIQEVIIELT--KGGVDFALDCAGGSETMKAALDCTTAGWGSCTFI---GVAA 302 D ++ ++++ ++ G +D + AG + LD + W + G Sbjct: 80 CQVDSYESCEKLVKDVVADFGQIDAFIANAGATAD-SGILDGSVEAWNHVVQVDLNGTFH 138 Query: 303 GSKGLTIFPEELIIGRTINGTFFGG 327 +K + +E G + G Sbjct: 139 CAKAVGHHFKERGTGSLVITASMSG 163 >6DLL-A nrPDB Length = 398 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 10/27 (37%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIG 227 A+ G G GL AG II Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIV 34 >3F9I-A nrPDB Length = 249 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 5/46 (10%) Query: 198 GSTCAVFGLG-GVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALG 242 G T + G G+G + G S++I N EK K+LG Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLG-SKVIISGSNEEKL---KSLG 55 >1LTH-T nrPDB Length = 319 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 195 VTPGSTCAVFGLGGVGLSAVMGCKAAG-ASRIIGIDINSEKFVK 237 V P AV G G VG + G A I+ DI E+ Sbjct: 5 VKPTK-LAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >3OC4-A nrPDB Length = 452 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 13/28 (46%) Query: 187 GAAINNAKVTPGSTCAVFGLGGVGLSAV 214 GA + T AV G G +G+ A+ Sbjct: 136 GALAAVPLLENSQTVAVIGAGPIGMEAI 163 >3JTM-A nrPDB Length = 351 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 16/49 (32%), Gaps = 1/49 (2%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 G T G G +G + K G + ++ D K GA Sbjct: 164 GKTIGTVGAGRIGKLLLQRLKPFGCN-LLYHDRLQMAPELEKETGAKFV 211 >5F8E-A nrPDB Length = 377 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 41/121 (33%), Gaps = 16/121 (13%) Query: 194 KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKF----VKAKALGATDCLNP 249 ++ G+ A FG G G + + +A GASR GID + E +A LG N Sbjct: 184 RLRSGADVADFGCGS-GRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLG---LANA 239 Query: 250 RDLHKPIQEVIIELTKGGVDF--ALDCA---GGSETMKAALDCTTAGWGSCTFIGVAAGS 304 + E+ G D D + + G + + A S Sbjct: 240 TFERHDLAELDK---VGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASS 296 Query: 305 K 305 + Sbjct: 297 Q 297 >4TXK-A nrPDB Length = 615 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 12/28 (42%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIG 227 C V G G GL A + GA ++ Sbjct: 86 KCLVVGAGPCGLRAAVELALLGARVVLV 113 >2BRY-A nrPDB Length = 497 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 12/28 (42%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIG 227 C V G G GL A + GA ++ Sbjct: 94 KCLVVGAGPCGLRAAVELALLGARVVLV 121 >4P8R-A nrPDB Length = 339 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 35/132 (26%), Gaps = 18/132 (13%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGI---------------DINSEKFVKAKAL-GA 243 + G G +G + I+GI D +F A + G Sbjct: 12 RVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGG 71 Query: 244 TDCLNPRDLHKPIQEVIIELTKGG--VDFALDCAGGSETMKAALDCTTAGWGSCTFIGVA 301 +N + + + L VD ++ G + A AG G + Sbjct: 72 ALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITGPS 131 Query: 302 AGSKGLTIFPEE 313 + + Sbjct: 132 KDDTPMFVMGVN 143 >4E4T-A nrPDB Length = 419 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 195 VTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINS 232 + PG+ + G G +G ++ G R+ +D + Sbjct: 32 ILPGAWLGMVGGGQLGRMFCFAAQSMG-YRVAVLDPDP 68 >3VZS-A nrPDB Length = 257 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 29/80 (36%), Gaps = 8/80 (10%) Query: 205 GLGGVGLSAVMGCKAAGASRIIGIDINSEK----FVKAKALGATDCLNPRDLHKPIQEVI 260 G+GG+G + G + G NS + + KALG + ++ Sbjct: 22 GMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDSTKT 81 Query: 261 I----ELTKGGVDFALDCAG 276 + G VD ++ AG Sbjct: 82 AFDKVKSEVGEVDVLINNAG 101 >5IM5-P nrPDB Length = 219 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 50/128 (39%), Gaps = 28/128 (21%) Query: 213 AVMGCKAAGASRIIGID--INSEKFVKAKALGATDCLNPR---DLHKPIQEVIIELTKGG 267 A+M ++A +IG +N + + AK GAT ++P + + Q + I++ G Sbjct: 52 AIMLLRSAQPEMLIGAGTILNGVQALAAKEAGATFVVSPGFNPNTVRACQIIGIDIVPG- 110 Query: 268 VDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGG 327 T++AAL+ G L FP E G ++ + G Sbjct: 111 -------VNNPSTVEAALEM---------------GLTTLKFFPAEASGGISMVKSLVGP 148 Query: 328 WKSVDSIP 335 + + +P Sbjct: 149 YGDIRLMP 156 >5OHX-A nrPDB Length = 504 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 25/65 (38%), Gaps = 2/65 (3%) Query: 189 AINNAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 A + + PG T G G+GL+ + ++ ++ EK ALGA Sbjct: 89 AEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKII 148 Query: 247 LNPRD 251 P + Sbjct: 149 RTPTE 153 >5UOG-A nrPDB Length = 344 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 52/175 (29%), Gaps = 15/175 (8%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRI---------IGIDINSEKFVKAKALGATDCLN 248 G T +FGLG +GL+ +A G S +G + A+A+ + Sbjct: 164 GRTVGLFGLGRIGLAIARRLEAFGVSIAYHTRTPREGLGFTYHPTLVGMAEAVDTLIVIV 223 Query: 249 PRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV------AA 302 P L+ G L G T+ A T G+ G+ Sbjct: 224 PGTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAALVTALQNGTIAGAGLDVFENEPN 283 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLP 357 + L FP ++ + + D + + + + L + Sbjct: 284 VPEALLSFPNVSLLPHVASASVVTRNAMSDLVVDNLKAWFSTGEALTPVAETPFR 338 >2X36-A nrPDB Length = 207 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 40/117 (34%), Gaps = 25/117 (21%) Query: 155 YTVVSDINLAKIDDDANLERVCLLGCGFSTG-----YGAAINNAKVTPGSTCAVFGLGGV 209 Y V S I+L + + A + GC T G + G ++ G Sbjct: 82 YLVTSHIHL-HVPEGATPKDGPSAGCTIVTALLSLAMGRPVRQNLAMTGE-VSLTG---- 135 Query: 210 GLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG 266 +I+ + EK + AK G T + P + K ++ +T+G Sbjct: 136 --------------KILPVGGIKEKTIAAKRAGVTCIVLPAENKKDFYDLAAFITEG 178 >4RDI-A nrPDB Length = 288 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 18/54 (33%) Query: 182 FSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKF 235 T ++ + V G+GGVG A G I ID++ Sbjct: 34 GGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCV 87 >3GG9-A nrPDB Length = 352 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 24/56 (42%) Query: 183 STGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKA 238 ST +V G T +FG G +G +A G + ++ NS++ +A Sbjct: 145 STTMPPNFGIGRVLKGQTLGIFGYGKIGQLVAGYGRAFGMNVLVWGRENSKERARA 200 >3MOG-A nrPDB Length = 483 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 26/66 (39%), Gaps = 2/66 (3%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258 T AV G G +G + G +++ DI++E +A G LN R + Sbjct: 6 QTVAVIGSGTMGAGIAEVAASHG-HQVLLYDISAEALTRAID-GIHARLNSRVTRGKLTA 63 Query: 259 VIIELT 264 E T Sbjct: 64 ETCERT 69 >1HL3-A nrPDB Length = 358 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 13/24 (54%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAG 221 G T + GLG VG + + KA G Sbjct: 171 GETLGIIGLGRVGQAVALRAKAFG 194 >3OSU-A nrPDB Length = 246 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 50/141 (35%), Gaps = 9/141 (6%) Query: 217 CKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAG 276 GASR IG I A+ G +N + + V+ E+ GVD A Sbjct: 7 ALVTGASRGIGRSI---ALQLAEE-GYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQAN 62 Query: 277 GSET--MKAALDCTTAGWGS--CTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVD 332 ++ +KA + + +GS L + +E I+ G + + Sbjct: 63 VADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQ 122 Query: 333 SI-PKLVTDYKNKKFNLDALV 352 P+++ NL ++V Sbjct: 123 KATPQMLRQRSGAIINLSSVV 143 >4FHN-X nrPDB Length = 450 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 29/154 (18%), Positives = 43/154 (27%), Gaps = 45/154 (29%) Query: 183 STGYG------AAINNAKVT-PGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN---- 231 +TGYG A + + G +V G G V A+ GA I D + Sbjct: 213 ATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVV 272 Query: 232 ------SEKFVK---------------AKALGATDCLNPRDLHKPI-------------Q 257 EK + AK G + P+ Sbjct: 273 DESGFTKEKLARLIEIKSSRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDV 332 Query: 258 EVIIELTKGGVDFALDCAGGSETMKAALDCTTAG 291 + +L GV + A T++A AG Sbjct: 333 DAAHQLIANGVKAVAEGANMPTTIEATELFQQAG 366 >5TUK-A nrPDB Length = 408 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 18/55 (32%), Gaps = 12/55 (21%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRII------------GIDINSEKFVKAKALG 242 V G G G + + G S I+ +DI AK++G Sbjct: 27 KILVIGAGIAGPAVCYWLRRFGFSPILVERCANLRKGGHAVDIRGVAIDLAKSMG 81 >3GG2-A nrPDB Length = 450 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFV 236 AV G+G VGL + GA+ + ID + K Sbjct: 5 IAVVGIGYVGLVSATCFAELGAN-VRCIDTDRNKIE 39 >4X4J-A nrPDB Length = 507 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT 244 + G G GL + AG ++ ++ + +++ LG T Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIG-VVVLERLPARTGESRGLGFT 67 >4L4S-H nrPDB Length = 339 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 196 TPGSTCAVFGLGGVGLS-AVMGCKAAGASRIIGIDINSEKFV 236 TP + V G+G VG++ A+ A + +D+ +K Sbjct: 17 TPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLK 58 >3X43-A nrPDB Length = 332 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 22/59 (37%), Gaps = 4/59 (6%) Query: 192 NAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGI---DINSEKFVKAKALGATDCL 247 + PG T G VG++ M A G R + + + E+ +A G L Sbjct: 57 KGLLKPGDTIVECTSGNVGIALAMVAAARG-YRFVAVMGDTYSVERRKLIRAYGGKLVL 114 >2HAE-A nrPDB Length = 386 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 25/86 (29%), Gaps = 24/86 (27%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDI-------------NSEKFVKAKALGATDC 246 V G+G G + V G ++ +D N A+ Sbjct: 184 KVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKGILNENDPETCLNEYHLEIAR------I 237 Query: 247 LNPRDLHKPIQEVIIELTKGGVDFAL 272 NP L ++ + G DF + Sbjct: 238 TNPERLSGDLETALE-----GADFFI 258 >3C3P-A nrPDB Length = 210 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 193 AKVTPGSTCAVFGLGGVGLSAVMGCKAAG-ASRIIGIDINSEKFVKAKAL 241 A++ V G G +G ++ +A +SR++ ID + + A+ + Sbjct: 52 ARIKQPQLVVVPGDG-LGCASWWFARAISISSRVVMIDPDRDNVEHARRM 100 >5D1F-A nrPDB Length = 413 Score = 28.5 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 16/37 (43%) Query: 1 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEV 37 +GT+ + AA+ P + + PP++ E Sbjct: 13 LGTENLYFQSNAALTRAVESPGQSQSDDAPPPRSGEA 49 >5VJ7-A nrPDB Length = 476 Score = 28.5 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 46/122 (37%), Gaps = 11/122 (9%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 G A+ G G GL+ G I ++ V G + P+++ ++ Sbjct: 154 GKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVL--TYGIPEFRLPKEI---LR 208 Query: 258 EVIIELTKGGVDFALD-CAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELII 316 + + +L+ GV+ D G + T++ L FIG AG+ L P + Sbjct: 209 KELKKLSLLGVEIKTDHIVGKTITIQELLQ-----EYDAVFIGTGAGTPKLPNIPGINLN 263 Query: 317 GR 318 G Sbjct: 264 GI 265 >4ZGS-A nrPDB Length = 386 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 12/34 (35%), Gaps = 1/34 (2%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINS 232 V G G +G A K G ++ DI Sbjct: 179 KVVGVVGTGAIGQQAARILKGIG-CKVFAYDIKP 211 >6DHM-A nrPDB Length = 582 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 19/41 (46%), Gaps = 3/41 (7%) Query: 194 KVTPG---STCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN 231 +TPG T AV G G VGL ++ GA + + + Sbjct: 318 GMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESD 358 >4EIQ-A nrPDB Length = 549 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 16/43 (37%) Query: 169 DANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGL 211 +A +E L+ G G A++ A G G G + Sbjct: 22 NAPIETDVLILGGGPVGMALALDLAHRQVGHLVVDAGDGTITH 64 >2GSX-A nrPDB Length = 951 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 42/297 (14%), Positives = 82/297 (27%), Gaps = 46/297 (15%) Query: 47 CHTDATVIDSKFEGLAFPVIVG----HEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKC 102 C + +++ + + P+ VG + +G IG DKV + KC Sbjct: 3 CGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKC 62 Query: 103 KF------CLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYT 156 ++ C P+ KI + + F+ G + + Sbjct: 63 EYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTR 122 Query: 157 VVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMG 216 + + +++ ++ C G+ + N + PG + G L Sbjct: 123 LPTCVSVFPLE--------CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI 174 Query: 217 CKAAGASRIIGIDINSEKFVKA--KALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDC 274 + + + +A K+LG N + PI V GV C Sbjct: 175 INCLSSGKWSAV---PPTCEEARCKSLG--RFPNGKVKEPPILRV-------GVTANFFC 222 Query: 275 AGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTI-------FPEELIIGRTINGTF 324 C G + + P ++ GR I + Sbjct: 223 -------DEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSL 272 >1CRW-G nrPDB Length = 333 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 19/135 (14%), Positives = 39/135 (28%), Gaps = 21/135 (15%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDI-----------------NSEKFVKAKAL 241 S + G G +G + GA + D K Sbjct: 1 SKIGINGFGRIGRLVLRAALEMGAQVVAVNDPFIALEYMVYMFKYDSTHGMFKGEVKAED 60 Query: 242 GATDCLNPRDLH--KPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG 299 GA ++ + + ++ I +K G ++ ++ G T++ A G I Sbjct: 61 GA-LVVDGKKITVFNEMKPENIPWSKAGAEYIVESTGVFTTIEKA-SAHFKGGAKKVIIS 118 Query: 300 VAAGSKGLTIFPEEL 314 + + + L Sbjct: 119 APSADAPMFVCGVNL 133 >3O8N-A nrPDB Length = 762 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 40/261 (15%), Positives = 82/261 (31%), Gaps = 23/261 (8%) Query: 82 VTNVKPG-DKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKG 140 VT++ G D V +C + +LC ++S ++ S ++ G Sbjct: 218 VTSLSCGADWVFIP------ECPPDDNWEDHLCRRLSETRTRGSRLNIIIVAEGAIDRNG 271 Query: 141 KPVYHFF-------GTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNA 193 KP+ ++ TV+ + + L A + Sbjct: 272 KPITSEGVKDLVVRRLGYDTRVTVLGHVQRGGTPSAFDR---ILGSRMGVEAVMALLEGT 328 Query: 194 KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLH 253 TP ++ G V L + + ++ + ++ ++F +A L +N +++ Sbjct: 329 PDTPACVVSLSGNQAVRLPLMECVQV---TKDVTKAMDEKRFDEAMKLRGRSFMNNWEVY 385 Query: 254 KPIQEVIIELTKGG-VDFALDCAGGSET-MKAALDC-TTAGWGSCTFIGVAAGSKGLTIF 310 K + + K G A+ G M AA+ G + V Sbjct: 386 KLLAHIRPPAPKSGSYTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGPAK 445 Query: 311 PEELIIGRTINGTFFGGWKSV 331 + G + G + G S Sbjct: 446 GQIEEAGWSYVGGWTGQGGSK 466 >3RWB-A nrPDB Length = 247 Score = 28.1 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 13/86 (15%) Query: 197 PGSTCAVFGLG-GVGLSAVMGCKAAGASRIIGIDINSEKF--------VKAKALGATDCL 247 G T V G G+G + A GA +I DIN+E KA+A+ A + Sbjct: 5 AGKTALVTGAAQGIGKAIAARLAADGA-TVIVSDINAEGAKAAAASIGKKARAIAAD--I 61 Query: 248 NPRDLHKPIQEVIIELTKGGVDFALD 273 + K + I LT GG+D ++ Sbjct: 62 SDPGSVKALFAEIQALT-GGIDILVN 86 >5IJZ-A nrPDB Length = 447 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 14/34 (41%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN 231 G V G G V A+ + GA+ I D + Sbjct: 233 GQKIIVSGSGNVATYAIEKAQELGATVIGFSDSS 266 >2YFH-A nrPDB Length = 448 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 31/91 (34%), Gaps = 13/91 (14%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN----------SEKFVKAKALGATDCL 247 G +V G G V A+ GA I D + EK + + A+ Sbjct: 231 GMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKASRDG 290 Query: 248 NPRDLHKPIQEVIIELTKG---GVDFALDCA 275 D K V +E + VD AL CA Sbjct: 291 RVADYAKEFGLVYLEGQQPWSLPVDIALPCA 321 >1YB2-A nrPDB Length = 275 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 26/71 (36%), Gaps = 2/71 (2%) Query: 194 KVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGAT--DCLNPRD 251 + PG G+G +S+ + G + ++ + + KA + D N R Sbjct: 107 GLRPGMDILEVGVGSGNMSSYILYALNGKGTLTVVERDEDNLKKAMDNLSEFYDIGNVRT 166 Query: 252 LHKPIQEVIIE 262 I + I + Sbjct: 167 SRSDIADFISD 177 >2GMH-A nrPDB Length = 584 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 23/68 (33%), Gaps = 2/68 (2%) Query: 201 CAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI 260 + G G GLSA K A D+ KA +GA + +E+ Sbjct: 38 VVIVGAGPAGLSAATRLKQLAAQH--EKDLRVCLVEKAAHIGAHTLSGACLDPRAFEELF 95 Query: 261 IELTKGGV 268 + + G Sbjct: 96 PDWKEKGA 103 >1WY7-A nrPDB Length = 207 Score = 28.1 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 17/43 (39%), Gaps = 2/43 (4%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240 G A G G G+ + G GA +I ++++ E Sbjct: 50 GKVVADLGAGT-GVLSY-GALLLGAKEVICVEVDKEAVDVLIE 90 >4XTI-A nrPDB Length = 413 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 36/111 (32%), Gaps = 18/111 (16%) Query: 207 GGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPR---------DLHKPIQ 257 G + + + + I ID + ++ G + ++ K I+ Sbjct: 126 GPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIK 185 Query: 258 EVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLT 308 E +L AG T + A AG IG+ +GS +T Sbjct: 186 ETFPDLQ--------VIAGNVVTREQAASLIHAG-ADGLRIGMGSGSICIT 227 >5JFC-L nrPDB Length = 474 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 10/29 (34%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRII 226 G A+ G G GL+ G I Sbjct: 154 GKKVAIIGAGPAGLTCAADLAKMGYEVTI 182 >4PRK-A nrPDB Length = 336 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDI 230 T + G+G +G + A GA +++ D+ Sbjct: 147 KTIGLIGVGHIGSAVAQIFSAMGA-KVLAYDV 177 >2AG5-A nrPDB Length = 246 Score = 28.1 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 23/62 (37%), Gaps = 3/62 (4%) Query: 216 GCKAAGASRIIGIDINSEKF-VKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDC 274 A +++I DIN K K G + K I + E+ + +D + Sbjct: 24 LAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVER--LDVLFNV 81 Query: 275 AG 276 AG Sbjct: 82 AG 83 >1MV8-A nrPDB Length = 436 Score = 28.1 bits (61), Expect = 6.8, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 200 TCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVK 237 ++FGLG VG A G +IG+D++S K Sbjct: 2 RISIFGLGYVGAVCAGCLSARG-HEVIGVDVSSTKIDL 38 >1XJ5-A nrPDB Length = 334 Score = 28.1 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 51/181 (28%), Gaps = 20/181 (11%) Query: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLH----- 253 V G GG G + A +I +I+ +K + D Sbjct: 122 KKVLVIG-GGDGGVLREVARHASIEQIDMCEIDKMVVDVSKQFFPDVAIGYEDPRVNLVI 180 Query: 254 KPIQEVIIELTKGGVDFAL----DCAGGSET------MKAALDCTTAGWGSCTFIGVAAG 303 + +G D + D G ++ ++ G CT + Sbjct: 181 GDGVAFLKNAAEGSYDAVIVDSSDPIGPAKELFEKPFFQSVARALRPGGVVCTQ--AESL 238 Query: 304 SKGLTIFPEELIIGRTI-NGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKIS 362 + I + + R I G+ W SV + P V + V P + I Sbjct: 239 WLHMDIIEDIVSNCREIFKGSVNYAWTSVPTYPSGVIGFMLCSTE-GPDVDFKHPLNPID 297 Query: 363 E 363 E Sbjct: 298 E 298 >1KZH-A nrPDB Length = 555 Score = 27.8 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%), Gaps = 4/41 (9%) Query: 175 VCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVM 215 +L TGY + I N + P GGV L+ +M Sbjct: 450 AVVLILNGLTGYMSCIKNLNLKPTDWI----AGGVPLTMLM 486 >1NP3-A nrPDB Length = 338 Score = 27.8 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 30/145 (20%), Positives = 46/145 (31%), Gaps = 6/145 (4%) Query: 198 GSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ 257 G A+ G G G + K +G +G+ S KA+A G + Sbjct: 16 GKKVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHG--LKVADVKTAVAAA 73 Query: 258 EVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIG 317 +V++ LT L +K A S + V + I G Sbjct: 74 DVVMILTPDEFQGRLYKEEIEPNLKKGATLAFAHGFSIHYNQVVPRADLDVIMIAPKAPG 133 Query: 318 RTINGTFFGGWKSVDSIPKLVTDYK 342 T+ F G IP L+ Y+ Sbjct: 134 HTVRSEFVKGG----GIPDLIAIYQ 154 >4V68-BC nrPDB Length = 191 Score = 27.8 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 22/65 (33%), Gaps = 8/65 (12%) Query: 233 EKFVKAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGW 292 EK +A+ GA +E+I ++ G +DF + G Sbjct: 58 EKIKEAEEAGADYV--------GGEEIIQKILDGWMDFVMGAVGSKLGRILGPRGLNPKA 109 Query: 293 GSCTF 297 G+ F Sbjct: 110 GTVGF 114 >5J5V-A nrPDB Length = 323 Score = 27.8 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 45/170 (26%), Gaps = 38/170 (22%) Query: 189 AINNAKVTPGSTCA--VFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDC 246 A + PG G G+ L+ V + + + ++ E+ KALGA Sbjct: 53 AEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLV 112 Query: 247 L-----------------------------------NPRDLHKPIQEVIIELTKGGVDFA 271 L NP K I E T G VD Sbjct: 113 LTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVF 172 Query: 272 LDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTIN 321 + G T+ G I VA + + + G I Sbjct: 173 IAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVI-AQALAGEEIK 221 >1MZJ-A nrPDB Length = 339 Score = 27.4 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 30/103 (29%), Gaps = 23/103 (22%) Query: 266 GGVDFALDCAGGSETMKAALDCTTAGWGSCTFI-----------------------GVAA 302 GG D + CAG + A D +G + G A Sbjct: 113 GGFDLSAACAGFCHALSIAADAVESGGSRHVLVVATERMTDVIDLADRSLSFLFGDGAGA 172 Query: 303 GSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKK 345 G + P + R I+GT G S + V D + Sbjct: 173 AVVGPSDVPGIGPVVRGIDGTGLGSLHMSSSWDQYVEDPSVGR 215 >3BIO-A nrPDB Length = 304 Score = 27.4 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 19/93 (20%) Query: 202 AVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQ--EV 259 A+ G G +G A+ + A I GI NP ++ +Q V Sbjct: 13 AIVGYGNIGRYALQALREAPDFEIAGIVRR----------------NPAEVPFELQPFRV 56 Query: 260 IIELTK-GGVDFALDCAGGSETMKAALDCTTAG 291 + ++ + VD AL C+ E + AL+ G Sbjct: 57 VSDIEQLESVDVALVCSPSREVERTALEILKKG 89 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.130 0.353 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,313,666 Number of Sequences: 36641 Number of extensions: 601669 Number of successful extensions: 3459 Number of sequences better than 10.0: 367 Number of HSP's better than 10.0 without gapping: 288 Number of HSP's successfully gapped in prelim test: 193 Number of HSP's that attempted gapping in prelim test: 2552 Number of HSP's gapped (non-prelim): 571 length of query: 380 length of database: 10,336,785 effective HSP length: 99 effective length of query: 281 effective length of database: 6,709,326 effective search space: 1885320606 effective search space used: 1885320606 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)