BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08246 (267 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1PPF-E nrPDB 435 e-123 1FUJ-A nrPDB 249 1e-66 1AE5-A nrPDB 189 1e-48 4Q7Y-A nrPDB 147 5e-36 1EUF-A nrPDB 137 3e-33 2V35-A nrPDB 137 5e-33 1ORF-A nrPDB 134 5e-32 1ELT-A nrPDB 130 5e-31 1FDP-A nrPDB 129 2e-30 2ZKS-A nrPDB 128 2e-30 1AZZ-A nrPDB 128 2e-30 5FCR-A nrPDB 126 8e-30 1FI8-A nrPDB 126 9e-30 1IAU-A nrPDB 126 1e-29 1KYN-A nrPDB 126 1e-29 1BRU-P nrPDB 124 4e-29 4H4F-A nrPDB 121 3e-28 1PYT-D nrPDB 121 3e-28 1UTJ-A nrPDB 121 3e-28 4DUR-A nrPDB 121 4e-28 3TK9-A nrPDB 119 9e-28 5UGG-A nrPDB 119 1e-27 1MZD-A nrPDB 118 2e-27 2RDL-A nrPDB 117 5e-27 3RP2-A nrPDB 116 8e-27 1NN6-A nrPDB 113 8e-26 3G01-A nrPDB 113 9e-26 1EQ9-A nrPDB 113 1e-25 3QUM-P nrPDB 113 1e-25 1A0J-A nrPDB 112 1e-25 2CGA-A nrPDB 110 7e-25 4AN7-A nrPDB 110 8e-25 1FON-A nrPDB 109 2e-24 1GVZ-A nrPDB 107 6e-24 2EEK-A nrPDB 105 3e-23 2BDH-A nrPDB 104 3e-23 1TON-A nrPDB 104 5e-23 1F7Z-A nrPDB 104 5e-23 5C67-A nrPDB 103 1e-22 1SGF-G nrPDB 102 2e-22 4WWY-A nrPDB 102 2e-22 5FXL-A nrPDB 102 2e-22 2F91-A nrPDB 102 2e-22 5TJX-A nrPDB 100 4e-22 4NFE-A nrPDB 100 5e-22 2TLD-E nrPDB 100 5e-22 3W94-A nrPDB 98 3e-21 6I44-A nrPDB 97 1e-20 1EKB-B nrPDB 96 2e-20 2PSX-A nrPDB 95 3e-20 3S9B-A nrPDB 95 3e-20 1NPM-A nrPDB 94 5e-20 1P57-B nrPDB 94 6e-20 3T2N-A nrPDB 94 8e-20 3E0N-B nrPDB 93 1e-19 1SPJ-A nrPDB 92 2e-19 5MS3-A nrPDB 92 2e-19 4MPW-A nrPDB 92 3e-19 1YC0-A nrPDB 91 4e-19 2F83-A nrPDB 91 5e-19 4LK4-A nrPDB 91 5e-19 3DFJ-A nrPDB 91 6e-19 4DGJ-A nrPDB 90 8e-19 2AIQ-A nrPDB 90 1e-18 1FIZ-A nrPDB 89 1e-18 1LTO-A nrPDB 89 1e-18 1FIW-A nrPDB 89 1e-18 3VGC-B nrPDB 89 2e-18 2R0L-A nrPDB 89 2e-18 6AOD-C nrPDB 88 3e-18 1AO5-A nrPDB 88 5e-18 4GSO-A nrPDB 87 1e-17 4E7N-A nrPDB 86 2e-17 3BSQ-A nrPDB 84 7e-17 1YM0-A nrPDB 83 1e-16 5GVT-A nrPDB 83 1e-16 1M9U-A nrPDB 82 2e-16 5ZFH-A nrPDB 82 2e-16 1FXY-A nrPDB 82 2e-16 1SGF-A nrPDB 82 4e-16 1BQY-A nrPDB 81 4e-16 1OP0-A nrPDB 80 7e-16 1X7A-C nrPDB 79 2e-15 4Z6A-H nrPDB 79 2e-15 1SI5-H nrPDB 79 3e-15 3LC3-A nrPDB 78 3e-15 3P8G-A nrPDB 77 8e-15 3S69-A nrPDB 77 8e-15 6QHB-A nrPDB 77 1e-14 2JET-B nrPDB 76 2e-14 2B9L-A nrPDB 75 2e-14 5XRF-A nrPDB 75 2e-14 5XW8-A nrPDB 75 3e-14 4XDE-A nrPDB 75 4e-14 5LHN-A nrPDB 74 4e-14 1PQ7-A nrPDB 74 7e-14 3F6U-H nrPDB 74 8e-14 2ASU-B nrPDB 73 1e-13 6BQM-A nrPDB 73 1e-13 4IGD-A nrPDB 73 2e-13 2HLC-A nrPDB 71 4e-13 5KWM-A nrPDB 69 2e-12 2PKA-B nrPDB 69 2e-12 1SC8-U nrPDB 67 6e-12 3H7O-A nrPDB 66 2e-11 3H7T-A nrPDB 66 2e-11 5LPF-A nrPDB 65 3e-11 2OQ5-A nrPDB 65 3e-11 4DJZ-B nrPDB 65 3e-11 2XXL-A nrPDB 64 6e-11 1C5M-D nrPDB 64 8e-11 5O32-I nrPDB 63 1e-10 1KIG-H nrPDB 62 2e-10 2XRC-A nrPDB 62 2e-10 1ZJK-A nrPDB 60 8e-10 1A5I-A nrPDB 60 8e-10 1Q3X-A nrPDB 60 1e-09 1MKW-K nrPDB 59 2e-09 1VR1-H nrPDB 59 2e-09 4NZQ-A nrPDB 59 2e-09 3NXP-A nrPDB 59 2e-09 1ETT-H nrPDB 59 3e-09 3K65-B nrPDB 58 4e-09 4FXG-H nrPDB 57 9e-09 5TO3-B nrPDB 56 2e-08 4BXW-A nrPDB 55 4e-08 1BDA-A nrPDB 55 5e-08 2OLG-A nrPDB 54 1e-07 2OCV-B nrPDB 52 2e-07 4KKD-A nrPDB 52 2e-07 3I77-A nrPDB 50 1e-06 2KAI-A nrPDB 50 1e-06 3BEU-A nrPDB 48 4e-06 1AKS-B nrPDB 48 5e-06 4IW4-E nrPDB 46 2e-05 1BBR-H nrPDB 44 7e-05 1EPT-B nrPDB 42 2e-04 2FMJ-A nrPDB 41 5e-04 1RIW-B nrPDB 39 0.003 3RU4-E nrPDB 36 0.016 2JET-C nrPDB 35 0.033 1P3E-A nrPDB 33 0.099 2HNT-C nrPDB 31 0.57 2HNT-F nrPDB 30 1.4 1BBR-E nrPDB 29 1.8 3F1S-B nrPDB 29 2.5 3H5C-B nrPDB 29 2.7 6MHY-A nrPDB 28 3.2 5O0W-A nrPDB 27 9.2 1VA0-A nrPDB 27 9.2 1F2J-A nrPDB 27 9.2 >1PPF-E nrPDB Length = 218 Score = 435 bits (1119), Expect = e-123, Method: Compositional matrix adjust. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV Sbjct: 61 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 120 Query: 150 QCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCN 209 QCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCN Sbjct: 121 QCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCN 180 Query: 210 GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ Sbjct: 181 GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1FUJ-A nrPDB Length = 221 Score = 249 bits (635), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 121/221 (54%), Positives = 161/221 (72%), Gaps = 3/221 (1%) Query: 30 IVGGRRARPHAWPFMVSLQLRG---GHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 IVGG A+PH+ P+M SLQ+RG HFCG TLI P+FV++AAHC+ ++ R V VVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 87 HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 HN+ +EPT+Q F+V ++F N YD N LNDI+++QL+ A ++A+V QLP Q + + Sbjct: 61 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPVP 120 Query: 147 NGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPL 206 +G QCLAMGWG +G + A VLQELNVTVVT CR N+CT V R+AG+CFGDSG PL Sbjct: 121 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 180 Query: 207 VCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 +C+G+I GI SFV GCA+ L+PD F VA +V+WI S ++ Sbjct: 181 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1AE5-A nrPDB Length = 225 Score = 189 bits (479), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 104/230 (45%), Positives = 140/230 (60%), Gaps = 8/230 (3%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGGR+ARP +PF+ S+Q +G HFCG LI FVM+AA C + N VVLGA++L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 90 SRRE-PTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 RRE +RQ F++ + ENGYDP LND+++LQL+ A + ++V + LP Q + G Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSNVCTLVRGRQAGVCFGDSGSPLV 207 +C GWG ++ + +NVTV CR +NVCT V R+ G+C GD G+PLV Sbjct: 121 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 180 Query: 208 CNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHP 257 C GL HG+ASF G C G PD F VA F +WID ++ +NP P P Sbjct: 181 CEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL----NNPGPGP 224 >4Q7Y-A nrPDB Length = 250 Score = 147 bits (371), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 89/245 (36%), Positives = 123/245 (50%), Gaps = 22/245 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG PH+ P+M S++ G H CG L+ +V+SAAHC ++ ++R VVLGAH L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 90 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPA-QGRRLGN 147 S EPT+QVF + + + Y P+ NDI +L+LNGSA + V + +LP + R Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTV---------------VTSLCRRSNVCTLVRG 192 G +C GWG + + L E V V +T LC RS Sbjct: 121 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSG-----DS 175 Query: 193 RQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDN 252 + G C DSG PLVC HG+ SF C PD + V+ FV WI +++RS Sbjct: 176 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQ 235 Query: 253 PCPHP 257 P P P Sbjct: 236 PGPLP 240 >1EUF-A nrPDB Length = 227 Score = 137 bits (346), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 82/234 (35%), Positives = 122/234 (52%), Gaps = 20/234 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GG A+PH+ P+M L + H CG L+ +FV++AAHC+ + ++ V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGS----SINVTLGA 56 Query: 87 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 HN+ RE T+QV V+R I Y+ L NDI++L+L A I V LP + Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS---LCRRSN------VCTLVRGRQAG 196 G+ C GWG LG N LQE+++ V + + R N +C ++ Sbjct: 117 KPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKN 176 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 GDSG PLVCNG+ GI S+ R G PD + ++ F++WI S ++R + Sbjct: 177 SFSGDSGGPLVCNGVAQGIVSYGRN---DGTTPDVYTRISSFLSWIHSTMRRYK 227 >2V35-A nrPDB Length = 240 Score = 137 bits (345), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 95/240 (39%), Positives = 130/240 (54%), Gaps = 26/240 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGG A+ ++WP +SLQ R G H CG TLI N+VM+AAHCV RVV+G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRE--LTFRVVVG 58 Query: 86 AHNLSRREPTRQVFAVQRIFENGY---DPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 HNL++ + T Q VQ+I + Y D V DI +L+L S T+N+ VQ+ LP G Sbjct: 59 EHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAG 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNV-TVVTSLC----------RRSNVCTLVR 191 L N C GWGL N +A LQ+ + TV ++C + S VC Sbjct: 119 TILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGD 178 Query: 192 GRQAGVCFGDSGSPLVC--NG--LIHGIASFV-RGGCASGLYPDAFAPVAQFVNWIDSII 246 G ++G C GDSG PL C NG +HG+ SFV R GC P F V+ +++WI+++I Sbjct: 179 GVRSG-CQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 >1ORF-A nrPDB Length = 234 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 82/236 (34%), Positives = 125/236 (52%), Gaps = 23/236 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG PH+ P+MV L L C LIA ++V++AAHC N+N R+ +V+LGAH++ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC--NLNKRS-QVILGAHSI 57 Query: 90 SRREPTRQVFAVQRIFENG-YDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 +R EPT+Q+ V++ F YDP D+ +LQL A IN V + LP +G + G Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPG 117 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN------------VC--TLVRGR 193 C GWG + + L+E+ +T++ +C N VC +L GR Sbjct: 118 TMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 177 Query: 194 QAGVCFGDSGSPLVCNGLIHGIASF-VRGGCASGLYPDAFAPVA-QFVNWIDSIIQ 247 + C GDSGSPL+C G+ G+ SF + C P + ++ + +NWI I+ Sbjct: 178 DS--CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >1ELT-A nrPDB Length = 236 Score = 130 bits (328), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 88/239 (36%), Positives = 129/239 (53%), Gaps = 25/239 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGGR A+P++WP+ +SLQ + G H CG +LI +VM+AAHCV + R RVVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSA--RTWRVVLG 58 Query: 86 AHNLSRREPTRQVFAVQRIF-ENGY--DPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 HNL+ E Q+ V +F +G+ D V DI +L+LN A++N+ VQ+A LP Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQEL------NVTVVTSLCRRSNVCTLV----RG 192 + L N C GWG ++ L++ + T +S S V T + G Sbjct: 119 QILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGG 178 Query: 193 RQAGVCFGDSGSPLVC--NG--LIHGIASFV-RGGCASGLYPDAFAPVAQFVNWIDSII 246 +G C GDSG PL C NG +HG+ SFV GC + P F V+ +++W++ I+ Sbjct: 179 ANSG-CNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >1FDP-A nrPDB Length = 235 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 76/229 (33%), Positives = 120/229 (52%), Gaps = 14/229 (6%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GGR A HA P+M S+QL G H CG L+A +V+SAAHC+ + V+V+LGAH+L Sbjct: 8 ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSL 67 Query: 90 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 S+ EP+++++ V R + P + +D+++LQL+ AT+ V+ R + G Sbjct: 68 SQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPG 127 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN----------VCTLVRGRQAGV 197 C GWG++ LQ + + V+ + C R +C R + Sbjct: 128 TLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDS-- 185 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG PLVC G++ G+ + C + P + VA + WIDS++ Sbjct: 186 CKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >2ZKS-A nrPDB Length = 240 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 81/234 (34%), Positives = 119/234 (50%), Gaps = 17/234 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GGR PH+ P+M SLQ G H CG L+ P +V++AAHC+A + +R+VLG H L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQ-RMAQLRLVLGLHTL 59 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLL-NDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 T + A I Y PV L ND+ +LQL+G + ++ LP++ + + G Sbjct: 60 DSPGLTFHIKAA--IQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAG 117 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSN----------VCTLVRGRQAGV 197 +C GWGL + ++ VL+EL++ V+ T +C S VC + Sbjct: 118 TRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQAP 177 Query: 198 CFGDSGSPLVCNG--LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 C GDSG PLVC ++ G+ SF C P VA +V+WI + RS Sbjct: 178 CKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRS 231 >1AZZ-A nrPDB Length = 226 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 79/226 (34%), Positives = 122/226 (53%), Gaps = 17/226 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG A P++WP +L + +FCG +LI+P ++++AAHC+ V VVLGAHN+ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGF--VDVVLGAHNI 58 Query: 90 SRREPTR-QVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E T+ + + Y+ + NDI +++L T+ A + LP+ +G G Sbjct: 59 REDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPS--TDVGVG 116 Query: 149 VQCLAMGWGLLGRNR-GIASVLQELNVTVVTS--------LCRRSNVCTLVRGRQAGVCF 199 GWGL + GI+ VL++++V ++++ + N+C G + G C Sbjct: 117 TVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICIDSTGGK-GTCN 175 Query: 200 GDSGSPLVCNGLIHGIASF-VRGGCASGLYPDAFAPVAQFVNWIDS 244 GDSG PL NGL +GI SF GC +G YPDAF V F++WI + Sbjct: 176 GDSGGPLNYNGLTYGITSFGAAAGCEAG-YPDAFTRVTYFLDWIQT 220 >5FCR-A nrPDB Length = 234 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 73/227 (32%), Positives = 126/227 (55%), Gaps = 11/227 (4%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 I+GG+ A HA P+M S+Q+ G H CG TL+ +V+SAAHC+ V + +V+V+LGAH+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 89 LSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 LS EP ++ + VQ + + G P +L +D+++ +L+ +A++ +V+ L + + + Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP 120 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR----RSNVCTL----VRGRQAGVC 198 G C GWG++ VL +L V+++ + C V T+ + C Sbjct: 121 GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAESNRRDTC 180 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSI 245 GDSGSPLVC + G+ ++ C +G P + V+ + WI++I Sbjct: 181 RGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENI 227 >1FI8-A nrPDB Length = 228 Score = 126 bits (317), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 75/235 (31%), Positives = 118/235 (50%), Gaps = 22/235 (9%) Query: 30 IVGGRRARPHAWPFMVSLQL----RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG A+PH+ P+M LQ+ G CG LI +FV++AAHC + ++V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS----KIQVTLG 56 Query: 86 AHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AHN+ +E +Q+ V +I + Y+ + NDI++L+L A ++ V+ LP + + Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS----------LCRRSNVCTLVRGRQ 194 + G C GWG LG + LQE+ +TV + + +C + Sbjct: 117 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 176 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GDSG PLVC + GI S+ G G P AF V+ F++WI +++S Sbjct: 177 RASFRGDSGGPLVCKKVAAGIVSY---GQNDGSTPRAFTKVSTFLSWIKKTMKKS 228 >1IAU-A nrPDB Length = 227 Score = 126 bits (317), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 80/233 (34%), Positives = 117/233 (50%), Gaps = 21/233 (9%) Query: 30 IVGGRRARPHAWPFMVSLQL---RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GG A+PH+ P+M L + + CG LI +FV++AAHC + ++ V LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS----SINVTLGA 56 Query: 87 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 HN+ +EPT+Q V+R I Y+P N NDI++LQL A VQ +LP+ ++ Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSN----------VCTLVRGRQA 195 G C GWG + LQE+ +TV S+ +C + Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 176 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GDSG PLVCN + GI S+ R +G+ P A V+ FV+WI ++R Sbjct: 177 TSFKGDSGGPLVCNKVAQGIVSYGRN---NGMPPRACTKVSSFVHWIKKTMKR 226 >1KYN-A nrPDB Length = 235 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 84/232 (36%), Positives = 121/232 (52%), Gaps = 23/232 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCV-ANVNVRAVRVVLG 85 I+GGR +RPH+ P+M LQ++ G CG L+ +FV++AAHC +N+NV LG Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINV-----TLG 55 Query: 86 AHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AHN+ RRE T+Q +R I Y+ + NDI++LQL+ N NV LP Sbjct: 56 AHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEG 115 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTV---------VTSLCRRSNVCTLVRGRQA 195 L G C GWG + RG L+E+ + V S R +C R + Sbjct: 116 LRPGTLCTVAGWGRVSMRRG-TDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERK 174 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GDSG PL+CN + HGI S+ G +SG+ P+ F V+ F+ WI + ++ Sbjct: 175 AAFKGDSGGPLLCNNVAHGIVSY---GKSSGVPPEVFTRVSSFLPWIRTTMR 223 >1BRU-P nrPDB Length = 241 Score = 124 bits (312), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 84/241 (34%), Positives = 120/241 (49%), Gaps = 27/241 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGG ARP++WP+ VSLQ H CG TL+ ++V++AAHC+++ R RVVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS--RTYRVVLG 58 Query: 86 AHNLSRREPTRQVFAVQRIFENGYDPVNLL---NDIVILQLNGSATINANVQVAQLPAQG 142 H+LS EP V ++ + N L NDI +L+L ++ +Q+ LPA G Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-----------SLCRRSNVCTLVR 191 L N C GWG L N +LQ+ + VV S + + +C Sbjct: 119 TILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGD 178 Query: 192 GRQAGVCFGDSGSPLVCNGL-----IHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDSI 245 G + C GDSG PL C G +HGI SF GC P F V+ +++WI+S+ Sbjct: 179 GIISS-CNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSV 237 Query: 246 I 246 I Sbjct: 238 I 238 >4H4F-A nrPDB Length = 249 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 87/240 (36%), Positives = 122/240 (50%), Gaps = 24/240 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGG ARPH+WP+ +SLQ H CG TLIA NFV++AAHC++ N R RV +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS--NTRTYRVAVG 58 Query: 86 AHNLSRREPTRQVF-AVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 143 +NL + +F V I ++ + L NDI +++L ++ +QVA LP + Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 144 RLGNGVQCLAMGWGLLGRNRGIASVLQE-LNVTVVTSLCRRSNVC------TLVRGRQAG 196 L C GWG L N IA LQ+ L V + C R + T+V G Sbjct: 119 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 178 Query: 197 V---CFGDSGSPLVC---NG--LIHGIASF-VRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 V C GDSG PL C NG + GI SF R GC + P + V+ +++WI+ +Q Sbjct: 179 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >1PYT-D nrPDB Length = 251 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 85/243 (34%), Positives = 124/243 (51%), Gaps = 23/243 (9%) Query: 26 LASEIVGGRRARPHAWPFMVSLQ-LRGG---HFCGATLIAPNFVMSAAHCVANVNVRAVR 81 L++ +VGG A PH+WP+ +SLQ LR H CG TLI PN V++AAHC++N R Sbjct: 10 LSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNT--LTYR 67 Query: 82 VVLGAHNLSRREPTRQVF-AVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLP 139 V LG +NL + ++ V IF ++ + NDI +++L + + +QVA LP Sbjct: 68 VALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLP 127 Query: 140 AQGRRLGNGVQCLAMGWGLLGRNRGIASVLQE-LNVTVVTSLCRRSNVC------TLVRG 192 ++G L C GWG L N IA+ LQ+ L V + C + + T+V Sbjct: 128 SEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCA 187 Query: 193 RQAGV---CFGDSGSPLVCNG----LIHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDS 244 GV C GDSG PL C + GI SF G C + P F V+ +++WI+ Sbjct: 188 GGDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQ 247 Query: 245 IIQ 247 +Q Sbjct: 248 KLQ 250 >1UTJ-A nrPDB Length = 242 Score = 121 bits (303), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 84/241 (34%), Positives = 121/241 (50%), Gaps = 21/241 (8%) Query: 19 LLLGGTALASE---IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV 75 +LL G A A+E IVGG +P++ P VSL G HFCG +L+ N+V+SAAHC + Sbjct: 7 VLLIGAAFATEDDKIVGGYECKPYSQPHQVSLN-SGYHFCGGSLVNENWVVSAAHCYKS- 64 Query: 76 NVRAVRVVLGAHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQ 134 V V LG HN+ E + Q + R+ + Y N+ NDI++++L+ AT+N VQ Sbjct: 65 ---RVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQ 121 Query: 135 VAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN-------- 185 LP G C GWG + ++ LQ LN+ +++ S C S Sbjct: 122 PVALPTSCAPA--GTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGMITNAM 179 Query: 186 VCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSI 245 C C GDSG P+VCNG + G+ S+ GCA P +A V F +W+ S Sbjct: 180 FCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGY-GCAEPGNPGVYAKVCIFNDWLTST 238 Query: 246 I 246 + Sbjct: 239 M 239 >4DUR-A nrPDB Length = 791 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 87/261 (33%), Positives = 128/261 (49%), Gaps = 29/261 (11%) Query: 9 CLFLACVLPALLLGGTALASE-----IVGGRRARPHAWPFMVSLQLR-GGHFCGATLIAP 62 C C P+ G + + +VGG A PH+WP+ VSL+ R G HFCG TLI+P Sbjct: 536 CDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISP 595 Query: 63 NFVMSAAHCVANV-NVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVIL 121 +V++AAHC+ + +V+LGAH EP Q V R+F +P DI +L Sbjct: 596 EWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLF---LEPTR--KDIALL 650 Query: 122 QLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-L 180 +L+ A I V A LP+ + + +C GWG G A +L+E + V+ + + Sbjct: 651 KLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG-AGLLKEAQLPVIENKV 709 Query: 181 CRRSNV-------CTLVRGRQAG---VCFGDSGSPLVC----NGLIHGIASFVRGGCASG 226 C R L G AG C GDSG PLVC ++ G+ S+ GCA Sbjct: 710 CNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARP 768 Query: 227 LYPDAFAPVAQFVNWIDSIIQ 247 P + V++FV WI+ +++ Sbjct: 769 NKPGVYVRVSRFVTWIEGVMR 789 >3TK9-A nrPDB Length = 226 Score = 119 bits (299), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 75/233 (32%), Positives = 117/233 (50%), Gaps = 22/233 (9%) Query: 30 IVGGRRARPHAWPFMVS---LQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GG A+PH+ P+M LQ + CG L+ +FV++AAHC + ++ V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGS----SINVTLGA 56 Query: 87 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 HN+ +E T+Q V+R I Y+P N N+I++LQL A V+ +LP+ ++ Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT----------SLCRRSNVCTLVRGRQA 195 G C GWG + + +A+ LQE+ +TV + R + +C + Sbjct: 117 KPGQLCSVAGWGYVSMST-LATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQ 175 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GDSG PLVC + GI S+ G G P + V+ F+ WI ++R Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSY---GNKKGTPPGVYIKVSHFLPWIKRTMKR 225 >5UGG-A nrPDB Length = 251 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 83/235 (35%), Positives = 120/235 (51%), Gaps = 24/235 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLR-GGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAH 87 +VGG A PH+WP+ VSL+ R G HFCG TLI+P +V++AAHC+ + +V+LGAH Sbjct: 22 VVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAH 81 Query: 88 NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 EP Q V R+F +P DI +L+L+ A I V A LP+ + + Sbjct: 82 QEVNLEPHVQEIEVSRLF---LEPTR--KDIALLKLSSPAVITDKVIPACLPSPNYVVAD 136 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSNV-------CTLVRGRQAG--- 196 +C GWG G A +L+E + V+ +C R L G AG Sbjct: 137 RTECFITGWGETQGTFG-AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTD 195 Query: 197 VCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PLVC ++ G+ S+ GCA P + V++FV WI+ +++ Sbjct: 196 SCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSRFVTWIEGVMR 249 >1MZD-A nrPDB Length = 240 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 76/237 (32%), Positives = 121/237 (51%), Gaps = 27/237 (11%) Query: 29 EIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNV-RAVRVVLGAH 87 EI+GG+ PH+ PFM S+Q G H CG LI P +V++AAHC ++ VVLGAH Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 88 NLSRREPTRQVFAVQRIFENG---YDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 +LS+ E ++Q +++ DP + NDI++++L +A +N +V++ + ++ Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQS--NDIMLVKLQTAAKLNKHVKMLHIRSK-TS 118 Query: 145 LGNGVQCLAMGWGLLGRNR-GIASVLQELNVTVVT-SLCR------------RSNVCTLV 190 L +G +C GWG + + L+E+ VTV++ LC + VC Sbjct: 119 LRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGD 178 Query: 191 RGRQAGVCFGDSGSPLVCNGLIHGIASFVRGG--CASGLYPDAFAPVA-QFVNWIDS 244 Q C GD+G PL+C G+ H I S GG C P + + ++ WI S Sbjct: 179 AKGQKDSCKGDAGGPLICKGVFHAIVS---GGHECGVATKPGIYTLLTKKYQTWIKS 232 >2RDL-A nrPDB Length = 226 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 75/233 (32%), Positives = 114/233 (48%), Gaps = 20/233 (8%) Query: 30 IVGGRRARPHAWPFMVSLQL--RGGHF--CGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG RPHA P+M L++ H C LI NFVM+AAHC R++ V+LG Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAG----RSITVLLG 56 Query: 86 AHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AHN +E T Q V++ F + YD +LNDI++L+L A + V + A+ Sbjct: 57 AHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNS 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV--------TSLCRRSNVCTLVRGRQAG 196 + G C A+GWG N + LQE+ + ++ + +C + Sbjct: 117 IPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIRN 176 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 V GDSG PL+C G+ GIAS+V P F ++ + WI+ I++ + Sbjct: 177 VYKGDSGGPLLCAGIAQGIASYVLRNAKP---PSVFTRISHYRPWINKILREN 226 >3RP2-A nrPDB Length = 224 Score = 116 bits (291), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 72/230 (31%), Positives = 111/230 (48%), Gaps = 20/230 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH----FCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG + PH+ P+M L + CG LI+ FV++AAHC R + V+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKG----REITVILG 56 Query: 86 AHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AH++ +RE T+Q V++ I Y+ V L+DI++L+L + V V LP+ Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLC--------RRSNVCTLVRGRQAG 196 + G C A GWG G + L+E+ + ++ + VC Sbjct: 117 IHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRA 176 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 GDSG PL+C G+ HGI S+ G P F V+ +V WI+++I Sbjct: 177 AFMGDSGGPLLCAGVAHGIVSY---GHPDAKPPAIFTRVSTYVPWINAVI 223 >1NN6-A nrPDB Length = 228 Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 74/237 (31%), Positives = 114/237 (48%), Gaps = 30/237 (12%) Query: 29 EIVGGRRARPHAWPFMVSLQLRGGH----FCGATLIAPNFVMSAAHCVANVNVRAVRVVL 84 EI+GG +PH+ P+M L++ + FCG LI NFV++AAHC R++ V L Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVTL 57 Query: 85 GAHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 143 GAHN++ E T Q V + F + Y+ L +DI++L+L A++ V P+Q Sbjct: 58 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 117 Query: 144 RLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRG----------- 192 + G C GWG G + + LQE+ + ++ C+ R Sbjct: 118 FVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMD-----PQACSHFRDFDHNLQLCVGN 172 Query: 193 -RQAGVCF-GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 R+ F GDSG PL+C G+ GI S+ R P F ++ + WI+ I+Q Sbjct: 173 PRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKP---PAVFTRISHYRPWINQILQ 226 >3G01-A nrPDB Length = 227 Score = 113 bits (282), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 76/233 (32%), Positives = 111/233 (47%), Gaps = 22/233 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLR--GGH--FCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG PH+ P+M + GG FCG L+ FV++AAHC R++ V LG Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKG----RSMTVTLG 56 Query: 86 AHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AHN+ +E T+Q+ V + I Y+P + NDI++L+L +A V+ LP + Sbjct: 57 AHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAH 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTV---------VTSLCRRSNVCTLVRGRQA 195 + G +C GWG + + L E+ +TV S R+N + + Sbjct: 117 VKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIK 176 Query: 196 GVCF-GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G F GDSG PLVC GI S+ G G P F V FV+WI ++ Sbjct: 177 GASFRGDSGGPLVCKRAAAGIVSY---GQTDGSAPQVFTRVLSFVSWIKKTMK 226 >1EQ9-A nrPDB Length = 222 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 80/229 (34%), Positives = 118/229 (51%), Gaps = 17/229 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 IVGG+ A +P+ VSL+L G H CGA+++ N V++AAHCV + N+ ++V +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 89 LSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 LS + V+ V+ + YD L ND+ ++ L N VQ +L L + Sbjct: 61 LSE---SGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLES 117 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTV-VTSLCRR-------SNVCTLVRGRQAGVCF 199 C GWG + LQE+ + V C R S++CTL + R G C Sbjct: 118 N-PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICTLTK-RGEGACH 175 Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GDSG PLV NG GI SF CA G PD + V+ FV+WI++ +++ Sbjct: 176 GDSGGPLVANGAQIGIVSF-GSPCALG-EPDVYTRVSSFVSWINANLKK 222 >3QUM-P nrPDB Length = 237 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 78/239 (32%), Positives = 116/239 (48%), Gaps = 28/239 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ P+ V + RG CG L+ P +V++AAHC+ N +V ++LG H+L Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV----ILLGRHSL 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSATINANVQVAQ 137 E T QVF V F + ++LL +D+++L+L+ A + V+V Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNRGIA-SVLQELNVTVVT-SLC-----RRSNVCTLV 190 LP Q LG C A GWG + + LQ +++ V++ +C ++ L Sbjct: 117 LPTQEPALGT--TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 174 Query: 191 RGRQAG---VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 GR G C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 175 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 >1A0J-A nrPDB Length = 223 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 76/228 (33%), Positives = 118/228 (51%), Gaps = 19/228 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG R ++ + SLQ G HFCG +LI+ +V+SAAHC + ++V LG HN+ Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKS----RIQVRLGEHNI 55 Query: 90 SRREPTRQ-VFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 + E T Q + +V+ I Y+ NL NDI++++L+ A++N+ V LP+ +G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCAS--SG 113 Query: 149 VQCLAMGWG-LLGRNRGIASVLQELNVTVVTSLCRRSNV---------CTLVRGRQAGVC 198 +CL GWG L G + L+ L++ +++S S C C Sbjct: 114 TRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSC 173 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 GDSG P+VCNG + G+ S+ GCA P + V + +WI S + Sbjct: 174 QGDSGGPVVCNGQLQGVVSWGY-GCAQRNKPGVYTKVCNYRSWISSTM 220 >2CGA-A nrPDB Length = 245 Score = 110 bits (275), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 76/236 (32%), Positives = 119/236 (50%), Gaps = 24/236 (10%) Query: 28 SEIVGGRRARPHAWPFMVSLQLRGG-HFCGATLIAPNFVMSAAHC-VANVNVRAVRVVLG 85 S IV G A P +WP+ VSLQ + G HFCG +LI N+V++AAHC V +V VV G Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV----VVAG 69 Query: 86 AHNLSRREPTRQVFAVQRIFENG-YDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 + Q + ++F+N Y+ + + NDI +L+L+ +A+ + V LP+ Sbjct: 70 EFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDD 129 Query: 145 LGNGVQCLAMGWGLL-GRNRGIASVLQELNVTVVTSL-CRR--------SNVCTLVRGRQ 194 G C+ GWGL N LQ+ ++ ++++ C++ + +C G Sbjct: 130 FAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVS 189 Query: 195 AGVCFGDSGSPLVC--NG--LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 + C GDSG PLVC NG + GI S+ C++ P +A V VNW+ + Sbjct: 190 S--CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTST-PGVYARVTALVNWVQQTL 242 >4AN7-A nrPDB Length = 231 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 78/229 (34%), Positives = 111/229 (48%), Gaps = 19/229 (8%) Query: 29 EIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 +IVGG ++ P+ VSL G HFCG +LI +V+SAAHC + ++V LG HN Sbjct: 8 KIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKS----RIQVRLGEHN 62 Query: 89 LSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 + E Q +I + ++ L NDI++++L+ AT+N+ V LP G Sbjct: 63 IDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAG- 121 Query: 148 GVQCLAMGWG-LLGRNRGIASVLQELNVTVVT-SLCRRSN--------VCTLVRGRQAGV 197 +CL GWG S+LQ L V++ S C+ S +C Sbjct: 122 -TECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDS 180 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG P+VCNG + GI S+ GCA P + V +VNWI I Sbjct: 181 CQGDSGGPVVCNGQLQGIVSWGY-GCAQKNKPGVYTKVCNYVNWIQQTI 228 >1FON-A nrPDB Length = 240 Score = 109 bits (272), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 81/240 (33%), Positives = 117/240 (48%), Gaps = 30/240 (12%) Query: 33 GRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 G A P++W + VSLQ H CG +LIAP++V++A HC++ R +VVLG ++ Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS--RTYQVVLGEYD 59 Query: 89 LSRREPTRQVFAVQ--RIFENGYDPVNLL---NDIVILQLNGSATINANVQVAQLPAQGR 143 S E + QV + +F + N + NDI +++L+ SA + VQ+A LP G Sbjct: 60 RSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGD 119 Query: 144 RLGNGVQCLAMGWGLLGRNRGIASVLQE-LNVTVVTSLC----------RRSNVCTLVRG 192 L N C GWG L + LQ+ L TV C +++ VC Sbjct: 120 ILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT 179 Query: 193 RQAGVCFGDSGSPLVC-----NGLIHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDSII 246 R C GDSG PL C + +HG+ SFV GC + P F V+ F++WID I Sbjct: 180 RSG--CNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 >1GVZ-A nrPDB Length = 237 Score = 107 bits (267), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 72/243 (29%), Positives = 116/243 (47%), Gaps = 30/243 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG H+ P+ V++ +G CG L+ P +V++AAHC+++ ++ LG HNL Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSD----DYQIWLGRHNL 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSATINANVQVAQ 137 S+ E T Q V F + ++LL +D+++L+L A I V++ Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGR--NRGIASVLQELNVTVVT-SLCRRSN--------V 186 LP Q +LG+ C GWGL+ NRG + LQ + + + + C R+ + Sbjct: 117 LPTQEPKLGS--TCYTSGWGLISTFTNRG-SGTLQCVELRLQSNEKCARAYPEKMTEFVL 173 Query: 187 CTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C R +C GDSG L+C+G+ GI S+ CA F V WI I Sbjct: 174 CATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETI 233 Query: 247 QRS 249 +++ Sbjct: 234 EKN 236 >2EEK-A nrPDB Length = 220 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 69/223 (30%), Positives = 107/223 (47%), Gaps = 18/223 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ VSL G HFCG +L++ ++V+SAAHC +V +RV LG H++ Sbjct: 1 IVGGYECTKHSQAHQVSLN-SGYHFCGGSLVSKDWVVSAAHCYKSV----LRVRLGEHHI 55 Query: 90 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E T Q + + + Y N+ NDI++++L AT+N V LP + + Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECA--ADA 113 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVT---------SLCRRSNVCTLVRGRQAGVCF 199 C GWG + LQ L++ +++ + +S C C Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQ 173 Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 GDSG P+VCNG++ G+ S+ GCA +P +A V W+ Sbjct: 174 GDSGGPVVCNGVLQGVVSWGY-GCAERDHPGVYAKVCVLSGWV 215 >2BDH-A nrPDB Length = 223 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 70/229 (30%), Positives = 110/229 (48%), Gaps = 18/229 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+ G PH+ P+ +L + FC L+ P +V+SAAHC N + + LG H+L Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLHSL 56 Query: 90 -SRREPTRQ-VFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 + +EP Q V A + Y+ L ND+++++L+ S + + ++ + +Q GN Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 116 Query: 148 GVQCLAMGWGLLGRNRGIASVLQ---------ELNVTVVTSLCRRSNVCTLVRGRQAGVC 198 CL GWGLL R + +VLQ E+ + L S C Q C Sbjct: 117 --SCLVSGWGLLANGR-MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSC 173 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GDSG PL+CNG + G+ SF + C P + + +F WI+ +Q Sbjct: 174 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >1TON-A nrPDB Length = 235 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 74/242 (30%), Positives = 125/242 (51%), Gaps = 30/242 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + ++ P+ V++ + CG LI P++V++AAHC +N +V+LG +NL Sbjct: 1 IVGGYKCEKNSQPWQVAV--INEYLCGGVLIDPSWVITAAHCYSN----NYQVLLGRNNL 54 Query: 90 SRREPTRQVFAVQRIFEN-GYDPV-----------NLLNDIVILQLNGSATINANVQVAQ 137 + EP Q V++ F + Y P+ + ND+++L L+ A I V+V Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNRGIAS-VLQELNVTVVTSL----CRRSNVCT--LV 190 LP + ++G+ CLA GWG + + S LQ +N+ ++++ + NV L Sbjct: 115 LPTKEPKVGS--TCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLC 172 Query: 191 RGRQAG---VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G G C GDSG PL+C+G++ GI S CA P +A + +F +WI +++ Sbjct: 173 AGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMK 232 Query: 248 RS 249 + Sbjct: 233 EN 234 >1F7Z-A nrPDB Length = 233 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 77/228 (33%), Positives = 111/228 (48%), Gaps = 19/228 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + ++ P+ VSL G HFCG +LI +V+SAAHC + ++V LG HN+ Sbjct: 11 IVGGYTCQENSVPYQVSLN-SGYHFCGGSLINDQWVVSAAHCYKS----RIQVRLGEHNI 65 Query: 90 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 + E Q +I ++ +D L NDI++++L+ +NA V LP+ G Sbjct: 66 NVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCAPAG-- 123 Query: 149 VQCLAMGWG-LLGRNRGIASVLQELNVTVV-TSLCRRSN--------VCTLVRGRQAGVC 198 QCL GWG L +LQ L+ ++ + C S VC C Sbjct: 124 TQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSC 183 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 GDSG P+VCNG + GI S+ GCA P + V +V+WI I Sbjct: 184 QGDSGGPVVCNGELQGIVSWGY-GCALPDNPGVYTKVCNYVDWIQDTI 230 >5C67-A nrPDB Length = 224 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 111/230 (48%), Gaps = 23/230 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG ++ P+ VSL G HFCG +LI+ +V+SAAHC ++V LG HN+ Sbjct: 1 IVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKT----RIQVRLGEHNI 55 Query: 90 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E Q +I + Y+ L NDI++++L+ A INA V LP G Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA--PPAAG 113 Query: 149 VQCLAMGWG-LLGRNRGIASVLQELNVTVVT-SLCRRSN----------VCTLVRGRQAG 196 +CL GWG L L+ L+ V+T + C+ S V L G+ + Sbjct: 114 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS- 172 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C D+G P+VCNG + G+ S+ GCA P + V +V+WI I Sbjct: 173 -CQRDAGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTI 220 >1SGF-G nrPDB Length = 237 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 67/242 (27%), Positives = 118/242 (48%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + ++ P+ V++ + CG L+ PN+V++AAHC + +V LG +NL Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDD----NYKVWLGKNNL 56 Query: 90 SRREPTRQV-FAVQRIFENGYD-----------PVNLLNDIVILQLNGSATINANVQVAQ 137 + EP+ Q F + I G++ + ND+++L+L+ A I V+ Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNR-GIASVLQELNVTVV-TSLCRRSNV-----CTLV 190 LP + +LG+ CLA GWG + + L +N+ ++ C ++++ L Sbjct: 117 LPTEEPKLGS--TCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLC 174 Query: 191 RGRQAG---VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G G C GDSG PL+C+G++ GI S+ C P + + +F +WI + Sbjct: 175 AGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMA 234 Query: 248 RS 249 ++ Sbjct: 235 KN 236 >4WWY-A nrPDB Length = 224 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 109/230 (47%), Gaps = 23/230 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG ++ P+ VSL G HFCG +LI +V+SA HC + ++V LG HN+ Sbjct: 1 IVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKS----RIQVRLGEHNI 55 Query: 90 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E Q +I + YD L NDI++++L+ A INA+V LP G Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPT--APPATG 113 Query: 149 VQCLAMGWG-LLGRNRGIASVLQELNVTVVT-SLCRRSN----------VCTLVRGRQAG 196 +CL GWG LQ L+ V++ + C S V L G+ + Sbjct: 114 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDS- 172 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C DSG P+VCNG + G+ S+ GCA P + V +V WI + I Sbjct: 173 -CQRDSGGPVVCNGQLQGVVSW-GDGCAQKNKPGVYTKVYNYVKWIKNTI 220 >5FXL-A nrPDB Length = 246 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 115/230 (50%), Gaps = 21/230 (9%) Query: 29 EIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 +IVGG + P+ VSL G HFCG +LI +V+SAAHC + ++V LG N Sbjct: 23 KIVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCYKS----GIQVRLGEDN 77 Query: 89 LSRREPTRQ-VFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 ++ E Q + A + I Y+ L NDI++++L +A++N+ V LP Sbjct: 78 INVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASA-- 135 Query: 148 GVQCLAMGWGLLGRNRGIA--SVLQELNVTVVT-SLCRR-------SNV-CTLVRGRQAG 196 G QCL GWG ++ G + VL+ L +++ S C+ SN+ C Sbjct: 136 GTQCLISGWGNT-KSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKD 194 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG P+VC+G + GI S+ GCA P + V +V+WI I Sbjct: 195 SCQGDSGGPVVCSGKLQGIVSW-GSGCAQKNKPGVYTKVCNYVSWIKQTI 243 >2F91-A nrPDB Length = 237 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 77/235 (32%), Positives = 109/235 (46%), Gaps = 25/235 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLR----GGHFCGATLIAPNFVMSAAHCVAN---VNVRAVRV 82 IVGG A +P+ +S Q HFCGA++ N+ ++A HCV N +++ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 83 VLGAHNLSRREPTRQVFAVQRIFENGYDPVNLL-NDIVILQLNGSATINANVQVAQLPAQ 141 V G ++S E + Q+ V +I + NLL NDI +L+L+GS T N NV LP Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 142 GRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL-CR---------RSNVCTLVR 191 G V + GWG VLQ++ V +V+ CR S +C V Sbjct: 121 GHTATGDV--IVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 192 GRQAGVCFGDSGSPLVCNG----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C GDSG PL + + GI S+ GCA YP + V+ V+WI Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGY-GCARPGYPGVYTEVSYHVDWI 232 >5TJX-A nrPDB Length = 263 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 71/248 (28%), Positives = 116/248 (46%), Gaps = 24/248 (9%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAV 80 T ++ IVGG + WP+ VSLQ++ H CG +LI +V++AAHC + ++ V Sbjct: 10 TKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 69 Query: 81 -RV---VLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVA 136 R+ +L ++++ P Q+ + I Y +DI +++L + Sbjct: 70 WRIYSGILELSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPI 127 Query: 137 QLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN---------V 186 LP++G C GWG I ++LQ++N+ +VT C++ V Sbjct: 128 SLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMV 187 Query: 187 CTLVRGRQAGVCFGDSGSPLVC--NGLIH--GIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C + C GDSG PLVC NG+ GI S+ GCA P + VA++++WI Sbjct: 188 CAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 246 Query: 243 DSIIQRSE 250 Q S+ Sbjct: 247 LEKTQSSD 254 >4NFE-A nrPDB Length = 237 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 76/239 (31%), Positives = 106/239 (44%), Gaps = 28/239 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ P+ V++ G CG L+ P +V++AAHC+ + +V LG HNL Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRHNL 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSATINANVQVAQ 137 E T Q V F + ++LL +D+++L+L+ A I V+V Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLG-----RNRGIASVLQEL--NVTVVTSLCRRSNVCTLV 190 LP Q LG C A GWG + R R + V L N + + L Sbjct: 117 LPTQEPALGT--TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 174 Query: 191 RGRQAG---VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 G G C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 175 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 233 >2TLD-E nrPDB Length = 220 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 78/229 (34%), Positives = 117/229 (51%), Gaps = 24/229 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + P+ VSL G HFCG +LI +V+SAAHC + ++V LG N+ Sbjct: 1 IVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCYKS----GIQVRLGEDNI 55 Query: 90 SRREPTRQ-VFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 + E Q + A + I Y+ L NDI++++L +A++N+ V LP G Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASA--G 113 Query: 149 VQCLAMGWGLLGRNRGIA--SVLQELNVTVVT-SLCRR-------SNV-CTLVRGRQAGV 197 QCL GWG ++ G + VL+ L +++ S C+ SN+ C + G + Sbjct: 114 TQCLISGWGNT-KSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGGDS-- 170 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG P+VC+G + GI S+ GCA P + V +V+WI I Sbjct: 171 CQGDSGGPVVCSGKLQGIVSW-GSGCAKNK-PGVYTKVCNYVSWIKQTI 217 >3W94-A nrPDB Length = 235 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 75/231 (32%), Positives = 105/231 (45%), Gaps = 19/231 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCV--ANVNVRAVRVVLGAH 87 +VGG A AWP+MVSL RG H CGA+LI +++++AAHCV N +++ VLG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 88 NLSRREPTR-QVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 S Q+ V RI N Y+ DI ++ L V L ++ + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR---------SNVCTLVRGRQA 195 G +C GWG + +LQE V +V C+R S +C Sbjct: 121 PAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGGV 180 Query: 196 GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C GDSG PL+C + G+ SF GC P A+A V+ F +WI Sbjct: 181 DSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTSWI 230 >6I44-A nrPDB Length = 627 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 70/248 (28%), Positives = 118/248 (47%), Gaps = 24/248 (9%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAV 80 T ++ IVGG ++ WP+ VSLQ++ H CG +LI +V++AAHC + ++ V Sbjct: 374 TKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 433 Query: 81 -RV---VLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVA 136 R+ +L ++++ P Q+ + I Y +DI +++L + Sbjct: 434 WRIYSGILQLSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPI 491 Query: 137 QLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN---------V 186 LP++G C GWG I ++LQ++N+ +VT C++ V Sbjct: 492 CLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMV 551 Query: 187 CTLVRGRQAGVCFGDSGSPLVC--NGL--IHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C + C GD+G PLVC NG+ + GI S+ GCA P + VA++++WI Sbjct: 552 CAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 610 Query: 243 DSIIQRSE 250 Q S+ Sbjct: 611 LEKTQSSD 618 >1EKB-B nrPDB Length = 235 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 73/236 (30%), Positives = 108/236 (45%), Gaps = 19/236 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVA--NVNVRAVRVVLGAH 87 IVGG +R AWP++V+L CGA+L++ ++++SAAHCV N+ + VLG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 88 NLSR-REPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 S P + + +I N Y+ NDI ++ L +Q LP + + Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR---------SNVCTLVRGRQA 195 G C GWG L A VLQE +V +++ C++ + VC Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEAGGV 180 Query: 196 GVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PL+C L+ G+ SF CA P +A V +F WI S + Sbjct: 181 DSCQGDSGGPLMCQENNRWLLAGVTSFGY-QCALPNRPGVYARVPRFTEWIQSFLH 235 >2PSX-A nrPDB Length = 227 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 72/230 (31%), Positives = 109/230 (47%), Gaps = 18/230 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH-FCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 I+ G H P+ +L LR +CGA L+ P ++++AAHC V RV LG ++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV----FRVRLGHYS 56 Query: 89 LSR-REPTRQVF-AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 LS E +Q+F V+ I GY ND+++++LN I V + Sbjct: 57 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLN--RRIRPTKDVRPINVSSHCPS 114 Query: 147 NGVQCLAMGWGLLGRNR-GIASVLQELNVTVVT------SLCRRSNVCTLVRGRQAG--V 197 G +CL GWG + VLQ LN++V++ + R+ + G +AG Sbjct: 115 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 174 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG P+VCNG + G+ S+ CA P + + +F WI IQ Sbjct: 175 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 >3S9B-A nrPDB Length = 234 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 71/245 (28%), Positives = 106/245 (43%), Gaps = 31/245 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 +VGG + PF+V+L C LI +V++AAHC + R +R+ LG H Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHC----DRRNIRIKLGMH 56 Query: 88 NLSRREPTRQV-------FAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA 140 + + R Q+ F + F NG D DI++++L T + ++ LP+ Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTKFPNGLD-----KDIMLIRLRRPVTYSTHIAPVSLPS 111 Query: 141 QGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR---------RSNVCTLV 190 + R G G +C MGWG + V N+ +V C +C + Sbjct: 112 RSR--GVGSRCRIMGWGKISTTT-YPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGI 168 Query: 191 RGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 C GDSG PL+CNG +HGI + C L P + V + NWI SII + Sbjct: 169 LKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGNR 228 Query: 251 DNPCP 255 CP Sbjct: 229 TVTCP 233 >1NPM-A nrPDB Length = 225 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 63/230 (27%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+ GR PH+ P+ +L CG L+ +V++AAHC + V LG H+L Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLGDHSL 56 Query: 90 -SRREPTRQVFAVQRIFE---NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 SR +P +++ Q I N +P + +DI++++L SA + V+ QL ++ Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKV 116 Query: 146 GNGVQCLAMGWGLLGR-NRGIASVLQELNVTVVT-SLCRRSNVCTLVRG-------RQAG 196 G +C+ GWG + + L V + + + C R+ + G A Sbjct: 117 GQ--KCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGAD 174 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG PLVC+G++ GI S+ C P + + ++ WI + Sbjct: 175 TCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1P57-B nrPDB Length = 255 Score = 94.0 bits (232), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 73/248 (29%), Positives = 107/248 (43%), Gaps = 27/248 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGGR WP+ VSL+ G H CG +L++ ++V++AAHC N R + A + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 90 SRREPTRQVFAVQR-IFENGYDPV------NLLNDIVILQLNGSATINANVQVAQLPAQG 142 ++ P VQ ++ GY P NDI ++ L+ + +Q LPA G Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRSN----------VCTLVR 191 + L +G C GWG A VLQE V ++++ +C ++ C Sbjct: 121 QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYP 180 Query: 192 GRQAGVCFGDSGSPLVCNGLIH--------GIASFVRGGCASGLYPDAFAPVAQFVNWID 243 C GDSG P VC I GI S+ GCA P + V+ F WI Sbjct: 181 EGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSDFREWIF 239 Query: 244 SIIQRSED 251 I+ + Sbjct: 240 QAIKTHSE 247 >3T2N-A nrPDB Length = 372 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 73/248 (29%), Positives = 106/248 (42%), Gaps = 27/248 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGGR WP+ VSL+ G H CG +L++ ++V++AAHC N R + A + Sbjct: 118 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 177 Query: 90 SRREPTRQVFAVQR-IFENGYDPV------NLLNDIVILQLNGSATINANVQVAQLPAQG 142 ++ P VQ ++ GY P NDI ++ L+ + +Q LPA G Sbjct: 178 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 237 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN----------VCTLVR 191 + L +G C GWG A VLQE V +++ +C ++ C Sbjct: 238 QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYP 297 Query: 192 GRQAGVCFGDSGSPLVCNGLIH--------GIASFVRGGCASGLYPDAFAPVAQFVNWID 243 C GDSG P VC I GI S+ GCA P + V+ F WI Sbjct: 298 EGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSDFREWIF 356 Query: 244 SIIQRSED 251 I+ + Sbjct: 357 QAIKTHSE 364 >3E0N-B nrPDB Length = 271 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 71/260 (27%), Positives = 111/260 (42%), Gaps = 26/260 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVR-AVRVVLGAHN 88 I GG A WP+ VS+ G H CG +L++ +V+SAAHC + + + A V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 89 LSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 L +V ++ I + Y DI +LQL+ T + ++ LPA N Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 148 GVQCLAMGWGLLGRNRGIAS--VLQELNVTVVT-----------------SLCRRSNVCT 188 G+ C GWG + + + + LQ+L V +++ + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCA 180 Query: 189 LVRGRQAGVCFGDSGSPLVC--NGLIH--GIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG PL C GL + GI S+ C + P + + + +WI S Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSW-GDACGARNRPGVYTLASSYASWIQS 239 Query: 245 IIQRSEDNPCPHPRDPDPAS 264 + + P ++ P S Sbjct: 240 KVTELQPRVVPQTQESQPDS 259 >1SPJ-A nrPDB Length = 238 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 29/243 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ P+ +L CG L+ +V++AAHC+++ ++ LG HNL Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISD----NYQLWLGRHNL 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSA-TINANVQVA 136 E T Q V F + ++LL +D+++L+L A TI V+V Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 137 QLPAQGRRLGNGVQCLAMGWGLLG-RNRGIASVLQELNVTVV-TSLCRRSNV-----CTL 189 +LP + +G+ CLA GWG + N LQ +++ ++ C++++V L Sbjct: 117 ELPTEEPEVGS--TCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFML 174 Query: 190 VRGRQAG---VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 G G C GDSG PL+C+G++ G+ S+ C + P V +V WI+ I Sbjct: 175 CVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 234 Query: 247 QRS 249 + Sbjct: 235 AEN 237 >5MS3-A nrPDB Length = 228 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 63/232 (27%), Positives = 106/232 (45%), Gaps = 23/232 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG +PH+ P+ +L CG L+ N+V++AAHC V LG H+L Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC----KKPKYTVRLGDHSL 56 Query: 90 SRRE-PTRQVFAVQRIFENGYDPVNLLN---DIVILQLNGSATINANVQVAQLPAQGRRL 145 ++ P +++ VQ I Y+ ++ + D+++LQL A++ + V+ L + Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT----SLCRRSNVCTLVRG-------RQ 194 G +C GWG + R + LN V C + + G + Sbjct: 117 GQ--KCTVSGWGTVTSPR--ENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG 172 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 A C GDSG PLVC+G + GI S+ C P + + ++++WI II Sbjct: 173 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >4MPW-A nrPDB Length = 245 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 71/250 (28%), Positives = 115/250 (46%), Gaps = 36/250 (14%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVAN--VNVRAVRVVL 84 IVGG+ A WP+ VSL++ G HFCG +LI P +V++AAHCV ++ A+RV L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 85 GAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 143 +L ++ Q+ V RI + + DI +L+L ++++V LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 144 RLGNGVQCLAMGWGLLGRNRGIAS--VLQELNVTVVTS------------------LCRR 183 G+ C GWG + + + L+++ V ++ + + R Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVC--NG--LIHGIASFVRGGCASGLYPDAFAPVAQFV 239 +C R + C GDSG PLVC NG L G+ S+ GCA P + V ++ Sbjct: 178 DMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYL 234 Query: 240 NWIDSIIQRS 249 +WI + + Sbjct: 235 DWIHHYVPKK 244 >1YC0-A nrPDB Length = 283 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 118/252 (46%), Gaps = 35/252 (13%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVR-AVRV 82 T L I+GG + P + P++ ++ + G FC +L+ +V+SAAHC ++ R +V V Sbjct: 30 TFLRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSV 88 Query: 83 VLGAHNLSRREPTRQVFAVQRIFENGYDPVNLL-------NDIVILQLNGS----ATINA 131 VLG H +R Q F +++ Y P L +D+V+++L AT + Sbjct: 89 VLGQHFFNRTTDVTQTFGIEK-----YIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQ 143 Query: 132 NVQVAQLPAQGRRLGNGVQCLAMGWGLLGRN-RGIASVLQELNVTVVTS-LCRRSNV--- 186 VQ LP G G +C GWG L N G +S L+E V +V C V Sbjct: 144 FVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGA 203 Query: 187 -------CTLVRGRQAGVCFGDSGSPLVC--NGL--IHGIASFVRGGCASGLYPDAFAPV 235 C ++ C GDSG PL C NG+ ++GI S+ GC P + V Sbjct: 204 DISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISW-GDGCGRLHKPGVYTRV 262 Query: 236 AQFVNWIDSIIQ 247 A +V+WI+ I+ Sbjct: 263 ANYVDWINDRIR 274 >2F83-A nrPDB Length = 625 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 69/238 (28%), Positives = 103/238 (43%), Gaps = 20/238 (8%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLRG---GHFCGATLIAPNFVMSAAHCVANVNV-RA 79 T + IVGG + WP+ V+L H CG ++I ++++AAHC V + Sbjct: 382 TKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKI 441 Query: 80 VRVVLGAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQL 138 +RV G N S + F VQ I + Y DI +L+L + + + L Sbjct: 442 LRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL 501 Query: 139 PAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR---------SNVCT 188 P++G R C GWG I + LQ+ + +VT C++ +C Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICA 561 Query: 189 LVRGRQAGVCFGDSGSPLVC--NGLIH--GIASFVRGGCASGLYPDAFAPVAQFVNWI 242 R C GDSG PL C N + H GI S+ GCA P + V ++V+WI Sbjct: 562 GYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 618 >4LK4-A nrPDB Length = 357 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 69/240 (28%), Positives = 117/240 (48%), Gaps = 28/240 (11%) Query: 26 LASEIVGGRRARPHAWPFMVSLQLRG-----GHFCGATLIAPNFVMSAAHCVANVNVRAV 80 ++S I+ G A WP +V+L RG G FCG + + +V++AAHC + + +V Sbjct: 7 ISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASV 66 Query: 81 RVVLGAHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLP 139 V++GA++L+ ++ A Q+I+ + Y P NLLNDI I++L ++++ A P Sbjct: 67 DVIIGAYDLNNSSQGERI-AAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPAITLAG--P 123 Query: 140 AQGRRLGNGVQCLAMGWGLLGRNR--GIASVLQELNVTVVT-SLCR------------RS 184 A L GWG+ +++ +LQE++V +V+ SLC+ + Sbjct: 124 ATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNST 183 Query: 185 NVCTLVRGRQAGVCFGDSGSPLVCNGLIH--GIASFVRGGCASGLYPDAFAPVAQFVNWI 242 N C + + C GD+G P+V GI S+ CA + V+ F +WI Sbjct: 184 NFCAARLTKDS--CQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWI 241 >3DFJ-A nrPDB Length = 263 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 68/244 (27%), Positives = 105/244 (43%), Gaps = 26/244 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVR-AVRVVLGAHN 88 I GG A WP+ VS+ G H CG +L++ +V+SAAHC + + + A V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 89 LSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 L +V ++ I + Y DI +LQL+ T + ++ LPA N Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 148 GVQCLAMGWGLLGRNRGIAS--VLQELNVTVVT-----------------SLCRRSNVCT 188 G+ C GWG + + + + LQ+L V +++ + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCA 180 Query: 189 LVRGRQAGVCFGDSGSPLVC--NGLIH--GIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG PL C GL + GI S+ C + P + + + +WI S Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSW-GDACGARNRPGVYTLASSYASWIQS 239 Query: 245 IIQR 248 + Sbjct: 240 KVTE 243 >4DGJ-A nrPDB Length = 235 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 66/236 (27%), Positives = 106/236 (44%), Gaps = 19/236 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVR--VVLGAH 87 IVGG A+ AWP++V L CGA+L++ ++++SAAHCV N+ + +LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 88 NLSRREPTRQV--FAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 S + V + + Y+ NDI ++ L +Q LP + + Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL-CRR---------SNVCTLVRGRQA 195 G C GWG + A +LQE +V ++++ C++ + +C Sbjct: 121 PPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGI 180 Query: 196 GVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PL+C + G+ SF CA P +A V++F WI S + Sbjct: 181 DSCQGDSGGPLMCQENNRWFLAGVTSFGY-ECALPNRPGVYARVSRFTEWIQSFLH 235 >2AIQ-A nrPDB Length = 231 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 68/242 (28%), Positives = 109/242 (45%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG + F+ +L G CG TLI +V++A HC + +R+ LG HNL Sbjct: 1 VIGGDECNINEHRFL-ALVYANGSLCGGTLINQEWVLTARHC----DRGNMRIYLGMHNL 55 Query: 90 S-------RREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 RR P + F + + +D DI++++LN +A++ LP+ Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWD-----KDIMLIRLNRPVRNSAHIAPLSLPSNP 110 Query: 143 RRLGNGVQCLAMGWGLLGR-NRGIASVLQELNVTVVT-SLCRR-------SNVCTLVRGR 193 +G+ C MGWG + N + V N+ ++ ++C+ + +C + Sbjct: 111 PSVGS--VCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEG 168 Query: 194 QAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNP 253 C GDSG PL+CNG GI S CA P + V + +WI SII + D Sbjct: 169 GKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGNTDAT 228 Query: 254 CP 255 CP Sbjct: 229 CP 230 >1FIZ-A nrPDB Length = 263 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 110/250 (44%), Gaps = 35/250 (14%) Query: 30 IVGGRRARPHAWPFMVSLQL------RGGHFCGATLIAPNFVMSAAHCVAN-VNVRAVRV 82 +VGG A P AWP+MVSLQ+ R H CG L+ ++V++AAHC N V R+ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 83 VLGAH------NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVA 136 + GA+ N + P ++ F + I Y +NDI ++++ + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 137 QLPAQGRRLGNGVQ-CLAMGWGLLGRNRG--IASVLQELNVTVVT-SLC----------R 182 LP Q C GWG L + +G + LQE V ++ LC R Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYL-KEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIR 179 Query: 183 RSNVCTLVRGRQAGVCFGDSGSPLVCNG------LIHGIASFVRGGCASGLYPDAFAPVA 236 +NVC + C GDSG PL+C ++ GI S+ GCA P + Sbjct: 180 STNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV-GCARAKRPGVYTSTW 238 Query: 237 QFVNWIDSII 246 ++NWI S I Sbjct: 239 PYLNWIASKI 248 >1LTO-A nrPDB Length = 245 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 112/250 (44%), Gaps = 36/250 (14%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVAN--VNVRAVRVVL 84 IVGG+ A WP+ VSL++R HFCG +LI P +V++AAHC+ ++ +RV L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 85 GAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 143 +L ++ Q+ V RI + + DI +L+L I++ V LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 144 RLGNGVQCLAMGWGLLGRNRGIAS--VLQELNVTVVTS------------------LCRR 183 G+ C GWG + + + L+++ V ++ + + R Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVC--NG--LIHGIASFVRGGCASGLYPDAFAPVAQFV 239 +C Q C GDSG PLVC NG L G+ S+ GCA P + V ++ Sbjct: 178 DMLCA--GNSQRDSCKGDSGGPLVCKVNGTWLQAGVVSWDE-GCAQPNRPGIYTRVTYYL 234 Query: 240 NWIDSIIQRS 249 +WI + + Sbjct: 235 DWIHHYVPKK 244 >1FIW-A nrPDB Length = 290 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 111/250 (44%), Gaps = 35/250 (14%) Query: 30 IVGGRRARPHAWPFMVSLQL------RGGHFCGATLIAPNFVMSAAHCV-ANVNVRAVRV 82 I+GG+ A AWP+MVSLQ+ R H CG +L+ ++++AAHC V R+ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 83 VLGAH------NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVA 136 + GA N + P ++ + + I Y + NDI ++++ T + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 137 QLPAQGRRLGNGV--QCLAMGWGLLGRN-RGIASVLQELNVTVVT-SLC----------R 182 LP Q R V C GWG L N R + +LQE V ++ LC R Sbjct: 121 CLP-QFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIR 179 Query: 183 RSNVCTLVRGRQAGVCFGDSGSPLVCNG------LIHGIASFVRGGCASGLYPDAFAPVA 236 +NVC + C GDSG PL+C ++ GI S+ GCA P + Sbjct: 180 STNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARAKRPGVYTSTW 238 Query: 237 QFVNWIDSII 246 ++NWI S I Sbjct: 239 SYLNWIASKI 248 >3VGC-B nrPDB Length = 131 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 48/132 (36%), Positives = 72/132 (54%), Gaps = 7/132 (5%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG-HFCGATLIAPNFVMSAAHC-VANVNVRAVRVVLGAH 87 IV G A P +WP+ VSLQ + G HFCG +LI N+V++AAHC V +V VV G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV----VVAGEF 56 Query: 88 NLSRREPTRQVFAVQRIFENG-YDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 + Q + ++F+N Y+ + + NDI +L+L+ +A+ + V LP+ Sbjct: 57 DQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFA 116 Query: 147 NGVQCLAMGWGL 158 G C+ GWGL Sbjct: 117 AGTTCVTTGWGL 128 >2R0L-A nrPDB Length = 248 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 76/246 (30%), Positives = 116/246 (47%), Gaps = 35/246 (14%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVR-AVRVVLGAHN 88 I+GG + P + P++ ++ + G FC +L+ +V+SAAHC ++ R +V VVLG H Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLL-------NDIVILQLNGS----ATINANVQVAQ 137 +R Q F +++ Y P L +D+V+++L AT + VQ Sbjct: 60 FNRTTDVTQTFGIEK-----YIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 114 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRN-RGIASVLQELNVTVVTS-LCRRSNV--------- 186 LP G G +C GWG L N G +S L+E V +V C V Sbjct: 115 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 174 Query: 187 -CTLVRGRQAGVCFGDSGSPLVC--NGL--IHGIASFVRGGCASGLYPDAFAPVAQFVNW 241 C ++ C GDSG PL C NG+ ++GI S+ GC P + VA +V+W Sbjct: 175 LCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISW-GDGCGRLHKPGVYTRVANYVDW 233 Query: 242 IDSIIQ 247 I+ I+ Sbjct: 234 INDRIR 239 >6AOD-C nrPDB Length = 245 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 66/232 (28%), Positives = 100/232 (43%), Gaps = 20/232 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRG---GHFCGATLIAPNFVMSAAHCVANVNV-RAVRVVLG 85 IVGG + WP+ V+L H CG ++I ++++AAHC V + +RV G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 86 AHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 S + F VQ I + Y DI +L+L + + + LP++G R Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR---------SNVCTLVRGRQ 194 C GWG I + LQ+ + +VT C++ +C R Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 195 AGVCFGDSGSPLVC--NGLIH--GIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C GD+G PL C N + H GI S+ GCA P + V ++V+WI Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 231 >1AO5-A nrPDB Length = 237 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 65/242 (26%), Positives = 115/242 (47%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 +VGG ++ P+ V++ + H CG L+ N+V++AAHC V V LG + L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY----VDQYEVWLGKNKL 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSATINANVQVAQ 137 + EP+ Q V + F + ++LL +D+++L+L+ A I V+ Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNRG-IASVLQELNVTVVTS-------LCRRSNV--C 187 LP + + G+ +CLA GWG + R LQ + +T++ + L + ++V C Sbjct: 117 LPTKEPKPGS--KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 174 Query: 188 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G C DSG PL+C+G++ G S+ C P + + +F +WI + Sbjct: 175 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 234 Query: 248 RS 249 ++ Sbjct: 235 KN 236 >4GSO-A nrPDB Length = 232 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/239 (28%), Positives = 108/239 (45%), Gaps = 21/239 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN- 88 ++GG + PF+ L G+FCG TLI +V++AAHC + ++ LG H+ Sbjct: 1 VLGGDECDINEHPFLAFL-YSHGYFCGLTLINQEWVVTAAHC----DSTNFQMQLGVHSK 55 Query: 89 --LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 L+ E TR + I N L DI++++L+ + + ++ LP+ +G Sbjct: 56 KVLNEDEQTRNP-KEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSVG 114 Query: 147 NGVQCLAMGWGLLG-RNRGIASVLQELNVTVVT-SLCR--------RSNVCTLVRGRQAG 196 + C MGWG + N V N+ +V +C+ ++ +C V Sbjct: 115 S--VCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKD 172 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 C GDSG PL+CNG GI S+ C G P + V + +WI I + D CP Sbjct: 173 TCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGNTDATCP 231 >4E7N-A nrPDB Length = 238 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 67/248 (27%), Positives = 106/248 (42%), Gaps = 33/248 (13%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 I+GG + F+V+L FCG TLI +V++AAHC + + R+ LG H Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHC----DRKNFRIKLGMH 56 Query: 88 -------NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA 140 + R P + F + +D DI++++L+ + + + +A Sbjct: 57 SKKVPNEDEQTRVPKEKFFCLSSKNYTLWD-----KDIMLIRLD--SPVKNSKHIAPFSL 109 Query: 141 QGRRLGNGVQCLAMGWGLLGRNRGI-ASVLQELNVTVVT-SLCR-----------RSNVC 187 G C MGWG + G V +N+ ++ +CR +C Sbjct: 110 PSSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLC 169 Query: 188 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 + C GDSG PL+CNG GIAS+ CA P A+ V ++WI++II Sbjct: 170 AGILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIA 229 Query: 248 RSEDNPCP 255 + D CP Sbjct: 230 GNTDASCP 237 >3BSQ-A nrPDB Length = 227 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 59/216 (27%), Positives = 97/216 (44%), Gaps = 17/216 (7%) Query: 42 PFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAV 101 P+ V+L CG L+ +V++AAHC N V LG+ L R R + A Sbjct: 13 PWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN----EYTVHLGSDTLGDRRAQR-IKAS 67 Query: 102 QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGR 161 + GY +ND+++++LN A +++ V+ +LP+ R G C GWG Sbjct: 68 KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS--RCEPPGTTCTVSGWGTTTS 125 Query: 162 -NRGIASVLQELNVTVVT---------SLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGL 211 + S L ++V +++ L S +C + + C GDSG PLVC G Sbjct: 126 PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGT 185 Query: 212 IHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 + G+ S+ C P + V +F WI+ ++ Sbjct: 186 LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1YM0-A nrPDB Length = 238 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 116/250 (46%), Gaps = 42/250 (16%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG--HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 IVGG ARP+ +P+ VS++ + HFCG ++I +V+ AAHC+ V +V+G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 88 NLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQ--VAQLPAQGRR 144 + S RQ V IF N YDP L ND+ +++ + T + NV A PA Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPAN-DY 119 Query: 145 LGNGVQCLAMGWGLLGRNRG---IASVLQELNVTVVTS----------------LCRRSN 185 + QC GWG + N G +VL+ + + + T+ +C N Sbjct: 120 VYRKSQC--SGWGTI--NSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDN 175 Query: 186 VCTLVRGRQAGVCFGDSGSPL-VCNGLIHGIASFV-----RGGCASGLYPDAFAPVAQFV 239 T + R + C GDSG PL V +G GI S V GCASG YP ++ V Sbjct: 176 --TGMTDRDS--CQGDSGGPLSVKDG--SGIFSLVGIVSWGIGCASG-YPGVYSRVGFHA 228 Query: 240 NWIDSIIQRS 249 WI I + Sbjct: 229 GWITDTITNN 238 >5GVT-A nrPDB Length = 250 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 60/242 (24%), Positives = 101/242 (41%), Gaps = 24/242 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 IVGG A WP+ VSLQ++ H CG ++I +V++AAHC + V + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 87 ----HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 +++ P+ ++ + I Y DI +++L + LP++ Sbjct: 61 ILSLSEITKETPSSRIKEL--IIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKA 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSN---------VCTLVRG 192 C GWG ++LQ+ + +V C++ +C + Sbjct: 119 DTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKE 178 Query: 193 RQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 C GDSG PLVC + GI S+ GCA P + V+++++WI Q Sbjct: 179 GGTDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKDQPGVYTKVSEYMDWILEKTQS 237 Query: 249 SE 250 S+ Sbjct: 238 SD 239 >1M9U-A nrPDB Length = 241 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/240 (28%), Positives = 105/240 (43%), Gaps = 30/240 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 ++GG A P +P+ +S Q + G H CGA+L++ +SA+HCV V +RV+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 87 HNLSRREPTRQVFAVQRIFENGYD--PVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 S T+ Y + NDI IL L S ++ N+Q A LPA Sbjct: 61 WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNN 120 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL-------------CRRSNVCTLVR 191 G C+ GWG + +LQ+ ++ V+T+ +++C Sbjct: 121 DYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQDP 180 Query: 192 GRQAGVCFGDSGSPLVC---NGLIHGIASFVRGGCASGL------YPDAFAPVAQFVNWI 242 G C GDSG PL C + G+ S+V +SGL YP + V+ ++ WI Sbjct: 181 AGNTGACNGDSGGPLNCPDGGTRVVGVTSWV---VSSGLGACLPDYPSVYTRVSAYLGWI 237 >5ZFH-A nrPDB Length = 224 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 19/224 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHF-CGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 I+ G + + + P+ V+L L+G CG L+ +V++AAHC + +V LG+ Sbjct: 1 IIDGYKCKEGSHPWQVAL-LKGNQLHCGGVLVDKYWVLTAAHC----KMGQYQVQLGSDK 55 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 + + +++ A + GY +NDI++++L+ +++ V+ QLP G Sbjct: 56 IGDQS-AQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCEP--PG 112 Query: 149 VQCLAMGWGLLGR-NRGIASVLQELNVTVVTS---------LCRRSNVCTLVRGRQAGVC 198 C GWG + S L +V +++S L ++ +C + + C Sbjct: 113 TSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTC 172 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 GDSG PLVCN + G+ S+ C P + V ++ W+ Sbjct: 173 NGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWV 216 >1FXY-A nrPDB Length = 228 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 69/231 (29%), Positives = 100/231 (43%), Gaps = 21/231 (9%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IVGG + P+ L FCG T+++ ++++AAHC+ VRV G N Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRV--GDRN 58 Query: 89 LSRREPTRQVFAVQRIFE-NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 + E V V+ + + N + DI +L+L T NV A LP Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTA--PPAT 116 Query: 148 GVQCLAMGWG-LLGRNRGIASVLQELNVTVVT-SLCRRSN----------VCTLVRGRQA 195 G +CL GWG LQ L+ V++ + C S V L G+ + Sbjct: 117 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDS 176 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG P+VCNG + G+ S+ GCA P + V +V WI + I Sbjct: 177 --CQGDSGGPVVCNGQLQGVVSW-GDGCAQKNKPGVYTKVYNYVKWIKNTI 224 >1SGF-A nrPDB Length = 240 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 61/223 (27%), Positives = 103/223 (46%), Gaps = 28/223 (12%) Query: 42 PFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQ---- 97 P+ V++ + CG L+ N+V++AAHC + +V LG +N EP+ Q Sbjct: 16 PWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYND----KYQVWLGKNNFLEDEPSDQHRLV 71 Query: 98 -------VFAVQRIFENGYDPVN-LLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 F + + E+ P + ND+++L+L+ A I V+ LP + +LG+ Sbjct: 72 SKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGS-- 129 Query: 150 QCLAMGWGLLGRNR-GIASVLQELNVTVV-TSLCRRSNV-----CTLVRGRQAG---VCF 199 CLA GWG + LQ +N+ ++ C +++ L G G C Sbjct: 130 TCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCE 189 Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 DSG PL+C+G++ GI S+ C P + + +F +WI Sbjct: 190 HDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWI 232 >1BQY-A nrPDB Length = 234 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 64/244 (26%), Positives = 110/244 (45%), Gaps = 29/244 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH-- 87 + GG + +V L G CG TLI ++V++AAHC +N +++ G H Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSN----NFQLLFGVHSK 56 Query: 88 -----NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 + R+P + F R ++ D DI++++L+ S + + ++ LP+ Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVD-----KDIMLIKLDSSVSNSEHIAPLSLPSSP 111 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIA-SVLQELNVTVVT-SLCR---------RSNVCTLVR 191 +G+ C MGWG + I V N+ ++ ++CR + +C + Sbjct: 112 PSVGS--VCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGIL 169 Query: 192 GRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSED 251 C DSG PL+CNG+ GI S+ C P + V +++WI SII ++D Sbjct: 170 QGGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGNKD 229 Query: 252 NPCP 255 CP Sbjct: 230 ATCP 233 >1OP0-A nrPDB Length = 234 Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 101/240 (42%), Gaps = 21/240 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN- 88 ++GG + F+V+ G FCG TLI P +V++AAHC + ++ LG H+ Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHC----DSTDFQMQLGVHSK 56 Query: 89 --LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 L+ E TR + I N + L DI++++L+ I+ + +A L Sbjct: 57 KVLNEDEQTRNP-KEKFICPNKNNNEVLDKDIMLIKLD--KPISNSKHIAPLSLPSSPPS 113 Query: 147 NGVQCLAMGWGLLGR-NRGIASVLQELNVTVVTS----------LCRRSNVCTLVRGRQA 195 G C MGWG + V N+ ++ L +C + Sbjct: 114 VGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGK 173 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 C GDSG PL+CNG GI S+ C G P + V + +WI I + D CP Sbjct: 174 DTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGNTDATCP 233 >1X7A-C nrPDB Length = 235 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 74/237 (31%), Positives = 111/237 (46%), Gaps = 29/237 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG A+P +P+ V L + FCG ++I +V++AAHC+ V+ + VV G +N Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCI-EPGVK-ITVVAGEYNT 58 Query: 90 SRREPTRQVFAVQR-IFENGYDPV--NLLNDIVILQLNGSATINANVQVAQLPAQGR--- 143 EPT Q V R I + Y+ +DI +L+L+ T+N+ V + + Sbjct: 59 EETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNI 118 Query: 144 --RLGNGVQCLAMGWG-LLGRNRGIASVLQELNVTVVT-SLCRRSNVCTLVR-----GRQ 194 + G+G GWG + R R A++LQ L V +V + C RS T+ G Sbjct: 119 FLKFGSG---YVSGWGRVFNRGRS-ATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFH 174 Query: 195 AG---VCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 G C GDSG P V + GI S+ G Y + V+++VNWI Sbjct: 175 EGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKY-GIYTKVSRYVNWIKE 230 >4Z6A-H nrPDB Length = 249 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 78/251 (31%), Positives = 110/251 (43%), Gaps = 20/251 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 IVGG+ P+ V L + G CG TLI +V+SAAHC + N R + VLG H+ Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 89 LSRREPTRQVFAV-QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG---RR 144 LS + Q V Q I + Y P +DI +L+L+ + +V LP + R Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVT-VVTSLCRRSN--------VCTLVRGRQA 195 L L GWG L A L LNV ++T C S C Sbjct: 121 LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGSK 180 Query: 196 GVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSED 251 C GDSG P + + GI S+ + GCA+ + + V+Q++ W+ ++ RSE Sbjct: 181 DSCKGDSGGPHATHYRGTWYLTGIVSWGQ-GCATVGHFGVYTRVSQYIEWLQKLM-RSEP 238 Query: 252 NPCPHPRDPDP 262 P R P P Sbjct: 239 RPGVLLRAPFP 249 >1SI5-H nrPDB Length = 240 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 64/220 (29%), Positives = 97/220 (44%), Gaps = 22/220 (10%) Query: 43 FMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRR--EPTRQVFA 100 +MVSL+ R H CG +LI ++V++A C + +++ LG H++ R E +QV Sbjct: 13 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 72 Query: 101 VQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLG 160 V ++ Y P +D+V+++L A ++ V LP G + C GWG G Sbjct: 73 VSQLV---YGPEG--SDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGYTG 127 Query: 161 --RNRGIASV--LQELNVTVVTSLCR------RSNVCTLVRGRQAGVCFGDSGSPLVCNG 210 G+ V L + + R S +C +G C GD G PLVC Sbjct: 128 LINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQ 187 Query: 211 ----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 ++ G+ R GCA P F VA + WI II Sbjct: 188 HKMRMVLGVIVPGR-GCAIPNRPGIFVRVAYYAKWIHKII 226 >3LC3-A nrPDB Length = 235 Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 72/238 (30%), Positives = 108/238 (45%), Gaps = 31/238 (13%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 +VGG A+P +P+ V L + FCG +++ ++++AAHCV V+ + VV G HN+ Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCV-ETGVK-ITVVAGEHNI 58 Query: 90 SRREPTRQVFAVQRIF--ENGYDPVNLLN-DIVILQLNGSATINANVQVAQLPAQGR--- 143 E T Q V RI N +N N DI +L+L+ +N+ V + + Sbjct: 59 EETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNI 118 Query: 144 --RLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSNVCTLVR--------- 191 + G+G GWG + A VLQ L V +V + C RS T+ Sbjct: 119 FLKFGSG---YVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHE 175 Query: 192 -GRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 GR + C GDSG P V + GI S+ G Y + V+++VNWI Sbjct: 176 GGRDS--CQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKY-GIYTKVSRYVNWIKE 230 >3P8G-A nrPDB Length = 241 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 105/238 (44%), Gaps = 28/238 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRG-GHFCGATLIAPNFVMSAAHCVANVNVRAVRV------ 82 +VGG A WP+ VSL G GH CGA+LI+PN+++SAAHC ++ R R Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCY--IDDRGFRYSDPTQW 58 Query: 83 --VLGAHNLSRRE-PTRQVFAVQRIFENG-YDPVNLLNDIVILQLNGSATINANVQVAQL 138 LG H+ S+R P Q ++RI + ++ DI +L+L A ++ V+ L Sbjct: 59 TAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 118 Query: 139 PAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGV- 197 P G GWG A +LQ+ + V+ + + + R V Sbjct: 119 PDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVG 178 Query: 198 --------CFGDSGSPLV---CNGLIH--GIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C GDSG PL +G I G+ S+ GCA P + + F +WI Sbjct: 179 FLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSW-GDGCAQRNKPGVYTRLPLFRDWI 235 >3S69-A nrPDB Length = 234 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 65/238 (27%), Positives = 102/238 (42%), Gaps = 15/238 (6%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG + +V+ G FC TLI +V++AAHC N N + V L Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHC-DNTNFQMKLGVHSKKVL 59 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 + E TR + I N + L DI++++L+ + + ++ LP+ +G+ Sbjct: 60 NEDEQTRNP-KEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSVGS-- 116 Query: 150 QCLAMGWGLLGRNR------GIASVLQELNVTVVTS-----LCRRSNVCTLVRGRQAGVC 198 C MGWG + + + + L+ V + L +C + C Sbjct: 117 VCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKDTC 176 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPH 256 GDSG PL+CNG GI SF C GL P + V + +WI SII + CP Sbjct: 177 GGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGNTTVTCPQ 234 >6QHB-A nrPDB Length = 223 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/216 (27%), Positives = 96/216 (44%), Gaps = 17/216 (7%) Query: 42 PFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAV 101 P+ +L G CG LI P +V++AAHC ++V LG HNL ++E +++ +V Sbjct: 13 PYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHNLGQQESSQEQSSV 68 Query: 102 QR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLG 160 R + YD + DI++L+L A ++ +Q LP + C +GWG Sbjct: 69 VRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ--PLPLERDCSAQTTSCHILGWGKTA 126 Query: 161 RNRGIASVLQELNVTVVT-SLCRRSN--------VCTLVRGRQAGVCFGDSGSPLVCNGL 211 + +Q + +V+ C + +C C GDSG PLVC Sbjct: 127 -DGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDH 185 Query: 212 IHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 + G+ S+ C S P + V ++ NWI IQ Sbjct: 186 LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >2JET-B nrPDB Length = 128 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 45/127 (35%), Positives = 65/127 (51%), Gaps = 5/127 (3%) Query: 33 GRRARPHAWPFMVSLQLRGG-HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSR 91 G A P +WP+ VSLQ + G HFCG +LI+ ++V++AAHC V V VV G + Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC--GVKTSDV-VVAGEFDQGS 57 Query: 92 REPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQ 150 E QV + ++F+N ++ + NDI +L+L A + V LP G Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 151 CLAMGWG 157 C GWG Sbjct: 118 CATTGWG 124 >2B9L-A nrPDB Length = 394 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/224 (28%), Positives = 106/224 (47%), Gaps = 35/224 (15%) Query: 55 CGATLIAPNFVMSAAHCVANV--NVRAVRVVLGAHN-LSRRE--PTRQVFAVQRIFENGY 109 CG +LIAP+ V++ AHCV + N+ A+++ G + L+ +E P ++ Q I + + Sbjct: 164 CGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNF 223 Query: 110 DPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGL--LGRNRGIAS 167 +P ++ND+ +L L+ N+ LP Q ++ + +C A GWG G ++ Sbjct: 224 NPKTVVNDVALLLLDRPLVQADNIGTICLPQQ-SQIFDSTECFASGWGKKEFGSRHRYSN 282 Query: 168 VLQELNV-TVVTSLCR---------------RSNVCTLVRGRQA-GVCFGDSGSPLVCNG 210 +L+++ + TV C+ ++ VC G Q C GD GSPL C Sbjct: 283 ILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVC--AGGEQGKDTCTGDGGSPLFCPD 340 Query: 211 -------LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 + GI ++ GC P +A VA F NWID +Q Sbjct: 341 PRNPSRYMQMGIVAWGI-GCGDENVPGVYANVAHFRNWIDQEMQ 383 >5XRF-A nrPDB Length = 242 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 19/214 (8%) Query: 55 CGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLS-RREPTRQVFAVQRIFENGYDPVN 113 C TLI +V++AAHC R + + LG HN S + + ++ +A++ + + + Sbjct: 34 CAGTLIHEEWVLAAAHCYK----RGLNIYLGMHNQSIQFDDEQRRYAIEEHYYRCDEKLT 89 Query: 114 LLN-DIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGI-ASVLQE 171 D+V+L+LN ++ + +A L G C MGWG++ + I V Sbjct: 90 KWEKDVVLLKLN--KPVSNSTHIAPLSLPSSPPSIGSVCRVMGWGIMSSTKDILPDVPHC 147 Query: 172 LNVTVVTSL---CRRSNVCTLVRGRQAGV-------CFGDSGSPLVCNGLIHGIASFVRG 221 N+ ++ + +V R AGV C DSG PL+C+G GI F + Sbjct: 148 ANINLLNYMECVAHYPDVPETTRLLCAGVLEGGIDTCNQDSGGPLICDGQFQGIVFFGKY 207 Query: 222 GCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 CA P + V+ + +WI +II CP Sbjct: 208 PCAQPNKPGLYTRVSNYNDWIQNIIAGKTTTACP 241 >5XW8-A nrPDB Length = 133 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 46/131 (35%), Positives = 69/131 (52%), Gaps = 8/131 (6%) Query: 28 SEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 +IVGG ++ P+ VSL G HFCG +LI +V+SAAHC + ++V LG H Sbjct: 7 DKIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKS----RIQVRLGEH 61 Query: 88 NLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 N+ E Q +I + ++ L NDI++++L+ AT+N+ V LP Sbjct: 62 NIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAA- 120 Query: 147 NGVQCLAMGWG 157 G +CL GWG Sbjct: 121 -GTECLISGWG 130 >4XDE-A nrPDB Length = 257 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 71/239 (29%), Positives = 102/239 (42%), Gaps = 28/239 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNV-RAVRVVLGAHN 88 +VGG A A P++ +L G FC +LIAP +V++AAHC+ + + VVLG Sbjct: 3 VVGGLVALRGAHPYIAALYW-GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 89 LSRREPTRQVFAVQRI-FENGYDPVNLLNDIVILQL----NGS-ATINANVQVAQLPAQG 142 + Q AV+ + PV+ +D+ +L+L +GS A ++ VQ LP+ Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 143 RRLGNGVQCLAMGWG-LLGRNRGIASVLQELNVTVVT-SLCRRSNV----------CTLV 190 R C GWG AS LQE V ++ C +V C Sbjct: 122 ARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGF 181 Query: 191 RGRQAGVCFGDSGSPLVCNG-------LIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C GDSG PLVC + GI S+ GC P + VA ++ WI Sbjct: 182 LEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISW-GSGCGDRNKPGVYTDVAYYLAWI 239 >5LHN-A nrPDB Length = 247 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 70/247 (28%), Positives = 106/247 (42%), Gaps = 31/247 (12%) Query: 30 IVGGRRARPHAWPFMVSL--QLRGGH----FCGATLIAPNFVMSAAHCVANVNVRAVRVV 83 IVGG P+ ++ + +GG CG +LI+P +V SAAHC + + VV Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 84 -LGAHNLSRREPTRQVFAVQRIFENGY---DPVNLLNDIVILQLNGS----ATINANVQV 135 LG S P F V+++ + Y D + NDI +L++ S A + ++Q Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 136 AQLPAQGRRLGNGVQCLAMGWG-------LLGRNRGIASVL-----QELNVTVVTSLCRR 183 LP + G C G+G L +N ++ V Q + S Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFV 239 +C + C GDSG PL+CN + GI S+ R GCA P + V+ F+ Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGR-GCAEKNKPGVYTRVSHFL 239 Query: 240 NWIDSII 246 +WI S I Sbjct: 240 DWIQSHI 246 >1PQ7-A nrPDB Length = 224 Score = 73.9 bits (180), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 69/229 (30%), Positives = 102/229 (44%), Gaps = 21/229 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG A +PF+VS+ GG +CG +L+ N V++AAHCV+ ++ G+ + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 + T + +V R+ + Y N ND+ IL+L+ S N+ A+L A G G Sbjct: 61 TSGGITSSLSSV-RVHPS-YSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPVAGS 116 Query: 150 QCLAMGWGLLGRNRGIASVLQELNVTV------------VTSLCRRSNVCTLVRGRQAGV 197 GWG G ++ + L VTV TS C V Sbjct: 117 SATVAGWGATSEG-GSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDS 175 Query: 198 CFGDSGSPLV--CNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG P+V N LI ++ GCA Y +A V ++ID+ Sbjct: 176 CQGDSGGPIVDSSNTLIGAVS--WGNGCARPNYSGVYASVGALRSFIDT 222 >3F6U-H nrPDB Length = 240 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 66/243 (27%), Positives = 109/243 (44%), Gaps = 29/243 (11%) Query: 30 IVGGRRARPHAWPF-MVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 ++ G+ R P+ +V L + CGA LI P++V++AAHC+ VR LG ++ Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVR--LGEYD 58 Query: 89 LSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG---RR 144 L R E ++ +F + Y NDI +L L AT++ + LP G R Sbjct: 59 LRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERE 118 Query: 145 LGN-GVQCLAMGWGL-------LGRNRGIASVLQELNV-------TVVTSLCRRSNVCTL 189 L G + L GWG RNR ++ V V++++ + +C Sbjct: 119 LNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAG 178 Query: 190 VRGRQAGVCFGDSGSPLVCNGLIHG---IASFVRGGCASGLYPD--AFAPVAQFVNWIDS 244 + G + C GDSG P+V + HG + V G GL + + V+++++WI Sbjct: 179 ILGDRQDACEGDSGGPMVAS--FHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHG 236 Query: 245 IIQ 247 I+ Sbjct: 237 HIR 239 >2ASU-B nrPDB Length = 234 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/236 (28%), Positives = 108/236 (45%), Gaps = 28/236 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG-HFCGATLIAPNFVMSAAHCVANVNV--RAVRVVLGA 86 +VGG P P+ VSL+ R G HFCG +L+ ++++A C ++ ++ V LG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 87 --HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 N EP+ Q V ++ + +V+L+L S T+N V + LP + Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSG-----SQLVLLKLERSVTLNQRVALICLPPEWYV 112 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL---------CRRSNVCTLVRGRQA 195 + G +C GWG + G +VL + V+++ R S +CT Sbjct: 113 VPPGTKCEIAGWGET-KGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPV 171 Query: 196 GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G C GD G PL C + ++ GI R CA +P F V+ FV+WI +++ Sbjct: 172 GACEGDYGGPLACFTHNSWVLEGIIIPNR-VCARSRWPAVFTRVSVFVDWIHKVMR 226 >6BQM-A nrPDB Length = 506 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 61/248 (24%), Positives = 108/248 (43%), Gaps = 31/248 (12%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCVANVNVRAVR 81 + ++S I+GG +A WP+MV+L R FCG + + +V++AAHCV + Sbjct: 5 SGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGD 64 Query: 82 VVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQ 141 V+LGA +++ ++ Q N Y ++ NDI +L+L +VQ++ + Sbjct: 65 VLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISD-SSD 123 Query: 142 GRRLGNGVQCLAMGWG----LLGRNRGIASVLQELNVTVV---------TSLCRRSNVCT 188 L +G+G + G A++L ++ V V + ++N Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 189 LVR--------GRQAGVCFGDSGSPLVC---NGLIH-GIASFVRGGCASGLYPDAFAPVA 236 L G+ A C GD+G P+ NG G+ S+ GC P + ++ Sbjct: 184 LTNNAFCAGSFGKDA--CSGDAGGPIFFDSNNGRKQMGVVSW-GDGCGRANSPGVYTNLS 240 Query: 237 QFVNWIDS 244 F +W+D Sbjct: 241 VFNDWLDD 248 >4IGD-A nrPDB Length = 406 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 61/233 (26%), Positives = 96/233 (41%), Gaps = 34/233 (14%) Query: 3 LGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSL-QLRGGHFCGATLIA 61 LGR L C LP L ++I GR A+ P++ L L G FCG +L+ Sbjct: 132 LGRSLPTCLPVCGLPKF---SRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLG 188 Query: 62 PNFVMSAAHCVAN--------------VNVRAVRVVLGAHNLSRREPTRQVFAVQR-IFE 106 +++++AAHC+ ++ +++LG H R + Q V+ Sbjct: 189 SSWIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLH 248 Query: 107 NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIA 166 YDP ND+ +++L S +NA V LP ++ G + GWG R Sbjct: 249 PQYDPNTFENDVALVELLESPVLNAFVMPICLPEGPQQ--EGAMVIVSGWGKQFLQR-FP 305 Query: 167 SVLQELNVTVVT-SLCR-----------RSNVCTLVRGRQAGVCFGDSGSPLV 207 L E+ + +V S C+ R +C + C GDSG P+V Sbjct: 306 ETLMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMV 358 >2HLC-A nrPDB Length = 230 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 109/232 (46%), Gaps = 29/232 (12%) Query: 30 IVGGRRARPHAWPFM----VSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+ G A +P+ ++LQ + +CG +LI ++++AAHCV + AV VV+ Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHD----AVSVVVY 56 Query: 86 AHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 + + E V + + I + ++P LND+ ++++ N+Q +LP+ G L Sbjct: 57 LGSAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKI-PHVEYTDNIQPIRLPS-GEEL 114 Query: 146 GNGVQCL---AMGWGLLGRNRGIASVLQELNVTVVTSLCRR---------SNVCTLVRGR 193 N + + GWG N + N+ + C + S +C Sbjct: 115 NNKFENIWATVSGWGQ--SNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSDG 172 Query: 194 QAGVCFGDSGSPLVCN--GLIHGIASFVRG-GCASGLYPDAFAPVAQFVNWI 242 ++ CFGDSG P V + L+ G+ SFV G GC SG P F+ V +++WI Sbjct: 173 KSP-CFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGK-PVGFSRVTSYMDWI 222 >5KWM-A nrPDB Length = 230 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 67/222 (30%), Positives = 94/222 (42%), Gaps = 17/222 (7%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IVGG A PF V+L G FCG TL APN V++AAHC + VV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 89 LSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 +S E T V V ++ + Y D+ +L L + A +++A+ G Sbjct: 61 MSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLE-APVKEAPIELAKADDAGYAPDT 117 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN--------VCTLVRGRQAGVC 198 L GWG A LQ+ V V + C+++ VC V C Sbjct: 118 AATIL--GWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVDTC 175 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVN 240 GDSG P+V N + G+ S+ GCA P +A V + + Sbjct: 176 QGDSGGPMVVNNKLIGVTSWGE-GCARPGKPGVYARVGAYYD 216 >2PKA-B nrPDB Length = 152 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 14/152 (9%) Query: 110 DPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVL 169 D + +D+++L+L A I V+V +LP Q LG+ C A GWG + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGS--TCEASGWGSIEPGPDDFEFP 59 Query: 170 QELNVTVVT----SLC--------RRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIAS 217 E+ +T + C S +C C GDSG PL+CNG+ GI S Sbjct: 60 DEIQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITS 119 Query: 218 FVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + C S P + + +++WID I + Sbjct: 120 WGHTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >1SC8-U nrPDB Length = 262 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 67/247 (27%), Positives = 103/247 (41%), Gaps = 34/247 (13%) Query: 29 EIVGGRRARPHAWPFMVSL--QLRGG---HFCGATLIAPNFVMSAAHCVANVNVRAVRVV 83 +I+GG P+ ++ + RGG + CG +LI+P +V+SA HC + + +V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 84 -LGAHNLSRREPTRQVFAVQR-IFENGY--DPVNLLNDIVILQLNGS----ATINANVQV 135 LG L+ F V+ I Y D + NDI +L++ A + +Q Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 136 AQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRS----------- 184 LP+ G C G+G N ++L +TVV + R Sbjct: 135 ISLPSMYNDPQFGTSCEITGFG--KENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEV 192 Query: 185 ---NVCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQ 237 +C + C GDSG PLVC+ + GI S+ R GCA P + V+ Sbjct: 193 TTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGR-GCALKDKPGVYTRVSH 251 Query: 238 FVNWIDS 244 F+ WI S Sbjct: 252 FLPWIRS 258 >3H7O-A nrPDB Length = 228 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 56/230 (24%), Positives = 98/230 (42%), Gaps = 15/230 (6%) Query: 32 GGRRARPHAWPFMVSLQLRGGH---FCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 GG + P+ V+++ G CG +++ FV++AAHCV + + + + N Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINA-NVQVAQLPAQGRRLGN 147 L +P + V ++ + Y + NDI IL+L+ ++ + A+LP R Sbjct: 62 L-WEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSNVCTLVR-----GRQAGVCF-- 199 G L G+G L+ +TVV CR + ++ GV Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLES 180 Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GD+G P V + G+A++ P+ F V +V+WI II++ Sbjct: 181 GDAGDPTVQQDTLVGVAAYFPKRPEGA--PEVFTKVGSYVSWIQDIIKKK 228 >3H7T-A nrPDB Length = 235 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 53/233 (22%), Positives = 96/233 (41%), Gaps = 21/233 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG+++ P+ V + + FCG +++ NFV++AA CV + + G+ Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS--- 57 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATI-NANVQVAQLPAQGRRLGNG 148 S R ++I+ Y P+ + N+ +++ + + + +LP+ Sbjct: 58 SYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPD 117 Query: 149 VQCLAMGWGLLG-RNRGIASVLQELNVTVVT-SLCRRSN-------------VCTLVRGR 193 L GWG ++ + L E N TVV C C Sbjct: 118 TSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEYD 177 Query: 194 QAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 + + +GD+G P V NG + G+AS++ + +P F V +V I II Sbjct: 178 ETYIGYGDAGDPAVQNGTLVGVASYISSMPSE--FPSVFLRVGYYVLDIKDII 228 >5LPF-A nrPDB Length = 234 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 57/224 (25%), Positives = 98/224 (43%), Gaps = 25/224 (11%) Query: 42 PFMVSLQLRGGHFCGATLIAPNFVMSAAHC-----VANVNVRAVRVVLGAHNLSRREPTR 96 P+ VSL C L+ ++V++AAHC A V + ++ G R TR Sbjct: 16 PWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQ---LRRTTR 72 Query: 97 QVFAVQRIFENGYDPV----NLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCL 152 V V + G P+ +D+++L+L + V+ QLP + + G+ QC Sbjct: 73 SV--VHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD--QCQ 128 Query: 153 AMGWGL-----LGRNRGIA----SVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSG 203 GWG + N+G+ ++L V +N+ R C DSG Sbjct: 129 VAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSG 188 Query: 204 SPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 PLVC+ + GI S+ C S +P + + ++++WI+ +I+ Sbjct: 189 GPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIR 232 >2OQ5-A nrPDB Length = 232 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 61/231 (26%), Positives = 89/231 (38%), Gaps = 19/231 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG WP+ SLQ G H CGATLI +++SAAHC A + Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 90 SRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 +P++ ++RI Y + DI + +L+ V LP G Sbjct: 61 ---KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPG 117 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSN----------VCTLVRGRQAGV 197 G+G L + + L++ VT++ + C +C + Sbjct: 118 DVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDA 177 Query: 198 CFGDSGSPLVCNGL--IHGIASFVRGG--CASGLYPDAFAPVAQFVNWIDS 244 C GDSG PLV + I +A V G CA P + V +WI S Sbjct: 178 CQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITS 228 >4DJZ-B nrPDB Length = 251 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 31/206 (15%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVAN-------------- 74 I GR A+ P++ L L G FCG +L+ +++++AAHC+ Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 75 VNVRAVRVVLGAHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANV 133 ++ +++LG H R + Q V+ YDP ND+ +++L S +NA V Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFV 120 Query: 134 QVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR---------- 182 LP ++ G + GWG R L E+ + +V S C+ Sbjct: 121 MPICLPEGPQQ--EGAMVIVSGWGKQFLQR-FPETLMEIEIPIVDHSTCQKAYAPLKKKV 177 Query: 183 -RSNVCTLVRGRQAGVCFGDSGSPLV 207 R +C + C GDSG P+V Sbjct: 178 TRDMICAGEKEGGKDACAGDSGGPMV 203 >2XXL-A nrPDB Length = 408 Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 66/283 (23%), Positives = 106/283 (37%), Gaps = 50/283 (17%) Query: 23 GTALASEIVGGRRARPHAWPFMVSLQLR----GGHFCGATLIAPNFVMSAAHCVANVNVR 78 G L+ + G + + P+M L+ + CG +I+ ++++AAHCV + Sbjct: 112 GNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQND 171 Query: 79 AVRVVLGAHNLSRREPTRQ-------------VFAVQRIFENGYDPVNLLNDIVILQLNG 125 + LG H +S E RQ V + + YD ++++DI +L+LN Sbjct: 172 LYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNR 231 Query: 126 SATINANVQVAQLPAQGRRLGNGVQC---LAMGWGLLGRNRGIASVLQELNV-----TVV 177 S +++ LP Q GWG N + VL + NV + Sbjct: 232 SVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPLQPRSAC 290 Query: 178 TSLCRR----SNVCTLVRGRQAGVCFGDSGSPLVC----------NGLIHGIASFVRGGC 223 + RR S +C + G C GDSG PL + GI S C Sbjct: 291 SQAYRRAVPLSQLC-VGGGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTC 349 Query: 224 ASGLYPDAFAPVAQFVNWIDSIIQRS---------EDNPCPHP 257 P + V ++V WI + + E P P+P Sbjct: 350 GQISLPGLYTNVGEYVQWITDTMASNGLLESRGPFEGKPIPNP 392 >1C5M-D nrPDB Length = 255 Score = 63.5 bits (153), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 62/232 (26%), Positives = 94/232 (40%), Gaps = 21/232 (9%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IVGG+ + P+ L FCG T+++ ++++AAHC+ VRV G N Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRV--GDRN 58 Query: 89 LSRREPTRQVFAVQRIFE-NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG---RR 144 + E V V+ + + N + DI +L+L T NV A LP + Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 118 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN--------VCTLVRGRQA 195 L + G+G ++ L+ L V V + C+ S+ C +Q Sbjct: 119 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQE 178 Query: 196 GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWID 243 C GDSG P V + GI S+ G G Y + V F+ WID Sbjct: 179 DACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKY-GIYTKVTAFLKWID 229 >5O32-I nrPDB Length = 244 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 54/239 (22%), Positives = 96/239 (40%), Gaps = 23/239 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG+RA+ P+ V+++ G CG I ++++AAHC+ ++ + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 90 SRREPTRQV--FAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQV-----AQLPAQG 142 + R V + + IF Y+ NDI ++++ + ++ A +P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGN-KKDCELPRSIPACVPWSP 119 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCR--------RSNVCTLVRGRQ 194 C+ GWG N + S LQ V ++++ + + C Sbjct: 120 YLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGS 178 Query: 195 AGVCFGDSGSPLVCNG-----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 C GDSG PLVC + G+ S+ C +P + VA + +WI + R Sbjct: 179 IDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHVGR 236 >1KIG-H nrPDB Length = 241 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 67/243 (27%), Positives = 98/243 (40%), Gaps = 35/243 (14%) Query: 30 IVGGRRARPHAWPF---MVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 IVGGR P+ +V+ + G FCG T++ +V++AAHC+ VRV G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEG--FCGGTILNEFYVLTAAHCLHQAKRFTVRV--GD 56 Query: 87 HNLSRREPTRQVFAVQ------RIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA 140 N + E V+ R + YD DI +L+L NV A LP Sbjct: 57 RNTEQEEGNEMAHEVEMTVKHSRFVKETYD-----FDIAVLRLKTPIRFRRNVAPACLPE 111 Query: 141 QG---RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN--------VCT 188 + L + G+G ++S L+ L V V S C+ S+ C Sbjct: 112 KDWAEATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCA 171 Query: 189 LVRGRQAGVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 + C GDSG P V + GI S+ GCA + V+ F+ WID Sbjct: 172 GYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKFGVYTKVSNFLKWIDK 230 Query: 245 IIQ 247 I++ Sbjct: 231 IMK 233 >2XRC-A nrPDB Length = 565 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 54/239 (22%), Positives = 96/239 (40%), Gaps = 23/239 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG+RA+ P+ V+++ G CG I ++++AAHC+ ++ + Sbjct: 322 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 381 Query: 90 SRREPTRQV--FAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQV-----AQLPAQG 142 + R V + + IF Y+ NDI ++++ + ++ A +P Sbjct: 382 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGN-KKDCELPRSIPACVPWSP 440 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCR--------RSNVCTLVRGRQ 194 C+ GWG N + S LQ V ++++ + + C Sbjct: 441 YLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGS 499 Query: 195 AGVCFGDSGSPLVCNG-----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 C GDSG PLVC + G+ S+ C +P + VA + +WI + R Sbjct: 500 IDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHVGR 557 >1ZJK-A nrPDB Length = 403 Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 69/258 (26%), Positives = 106/258 (41%), Gaps = 33/258 (12%) Query: 14 CVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVA 73 C L A GG +I GG++A+P +P+ V + GG L+ N+V++AAH V Sbjct: 151 CGLSARTTGG-----QIYGGQKAKPGDFPWQV--LILGGTTAAGALLYDNWVLTAAHAVY 203 Query: 74 NVNVRAVRVVLGAHNLSRREP-TRQVFAVQRIFENGYD-PVNLLNDIVILQLNGSATINA 131 A + + L R P Q ++ GY NDI +++LN IN+ Sbjct: 204 EQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINS 263 Query: 132 NVQVAQLPAQGRR--LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR------ 182 N+ LP + + A GWGL R +A L +++ +V C Sbjct: 264 NITPICLPRKEAESFMRTDDIGTASGWGLTQRGF-LARNLMYVDIPIVDHQKCTAAYEKP 322 Query: 183 ---RSNVCT--LVRGRQAG---VCFGDSGSPLVC------NGLIHGIASFVRGGCASGLY 228 R +V L G ++G C GDSG LV + GI S+ C Sbjct: 323 PYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQ 382 Query: 229 PDAFAPVAQFVNWIDSII 246 + V ++ WI++II Sbjct: 383 YGVYTKVINYIPWIENII 400 >1A5I-A nrPDB Length = 265 Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 65/236 (27%), Positives = 93/236 (39%), Gaps = 33/236 (13%) Query: 39 HAWPFMVSLQLR---GGHF-CGATLIAPNFVMSAAHCVANVNV-RAVRVVLGAHNLSRRE 93 H W + Q R G F CG LI+ +V++AAHC + ++VVLG + Sbjct: 25 HPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKPG 84 Query: 94 PTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGS----ATINANVQVAQLPAQGRRLGNG 148 Q F V++ I +D NDI +LQL A + +V+ LP +L + Sbjct: 85 EEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLPEANLQLPDW 144 Query: 149 VQCLAMGWGLLGRNRGIASV-LQE----------------LNVTVVTS-LCRRSNVCTLV 190 +C G+G + S L+E N TV + LC + Sbjct: 145 TECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLCAGDTRSGEI 204 Query: 191 RGRQAGVCFGDSGSPLVCNGLIH----GIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C GDSG PLVC H GI S+ GC P + V ++ WI Sbjct: 205 YPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEKDVPGVYTKVTNYLGWI 259 >1Q3X-A nrPDB Length = 328 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 69/259 (26%), Positives = 105/259 (40%), Gaps = 33/259 (12%) Query: 14 CVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVA 73 C L A GG I GG++A+P +P+ V + GG L+ N+V++AAH V Sbjct: 76 CGLSARTTGG-----RIYGGQKAKPGDFPWQV--LILGGTTAAGALLYDNWVLTAAHAVY 128 Query: 74 NVNVRAVRVVLGAHNLSRREP-TRQVFAVQRIFENGYD-PVNLLNDIVILQLNGSATINA 131 A + + L R P Q ++ GY NDI +++LN IN+ Sbjct: 129 EQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINS 188 Query: 132 NVQVAQLPAQGRR--LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR------ 182 N+ LP + + A GWGL R +A L +++ +V C Sbjct: 189 NITPICLPRKEAESFMRTDDIGTASGWGLTQRGF-LARNLMYVDIPIVDHQKCTAAYEKP 247 Query: 183 ---RSNVCT--LVRGRQAG---VCFGDSGSPLVC------NGLIHGIASFVRGGCASGLY 228 R +V L G ++G C GDSG LV + GI S+ C Sbjct: 248 PYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQ 307 Query: 229 PDAFAPVAQFVNWIDSIIQ 247 + V ++ WI++II Sbjct: 308 YGVYTKVINYIPWIENIIS 326 >1MKW-K nrPDB Length = 308 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 67/266 (25%), Positives = 110/266 (41%), Gaps = 39/266 (14%) Query: 21 LGGTALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ 72 L + + IV G+ A P+ V L + CGA+LI+ +V++AAHC+ Sbjct: 41 LFESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWD 100 Query: 73 ANVNVRAVRVVLGAHNLSRRE-PTRQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATI 129 N V + V +G H+ +R E ++ + +I+ Y+ NL DI +L+L + Sbjct: 101 KNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIEL 160 Query: 130 NANVQVAQLPAQ---GRRLGNGVQCLAMGWGLLGRNRGIA------SVLQELNVTVVTS- 179 + + LP + + L G + GWG + SVLQ +N+ +V Sbjct: 161 SDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERP 220 Query: 180 LCRRSNVCTLV-----------RGRQAGVCFGDSGSPLVCNGLIH------GIASFVRGG 222 +C+ S + G++ C GDSG P V + GI S+ G Sbjct: 221 VCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGC 280 Query: 223 CASGLYPDAFAPVAQFVNWIDSIIQR 248 G Y + V + WI +I R Sbjct: 281 DRDGKY-GFYTHVFRLKKWIQKVIDR 305 >1VR1-H nrPDB Length = 261 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 59/231 (25%), Positives = 98/231 (42%), Gaps = 37/231 (16%) Query: 54 FCGATLIAPNFVMSAAHCV------ANVNVRAVRVVLGAHNLSRREPT-RQVFAVQRIF- 105 CGA+LI+ +V++AAHC+ N + V +G H+ +R E ++ +++I+ Sbjct: 31 LCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYI 90 Query: 106 ENGYD-PVNLLNDIVILQLNGSATINANVQVAQLPAQ---GRRLGNGVQCLAMGWGLLGR 161 Y+ NL DI +++L + + LP + L G + GWG L Sbjct: 91 HPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 150 Query: 162 N------RGIASVLQELNVTVVTS-LCRRSN--------VCTLVR---GRQAGVCFGDSG 203 +G SVLQ +N+ +V +C+ S C + G++ C GDSG Sbjct: 151 TWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGDSG 210 Query: 204 SPLVCNGLIH------GIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 P V + GI S+ G G Y + V + WI +I + Sbjct: 211 GPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY-GFYTHVFRLKKWIQKVIDQ 260 >4NZQ-A nrPDB Length = 557 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 65/257 (25%), Positives = 106/257 (41%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 299 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 358 Query: 82 VVLGAHNLSRREPT-RQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ +++I+ Y+ NL DI +++L + + L Sbjct: 359 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 418 Query: 139 PAQ---GRRLGNGVQCLAMGWGLLGRN------RGIASVLQELNVTVVTS-LCRRSNVCT 188 P + L G + GWG L +G SVLQ +N+ +V +C+ S Sbjct: 419 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 478 Query: 189 LV-----------RGRQAGVCFGDSGSPLVCNGLIH------GIASFVRGGCASGLYPDA 231 + G++ C GDSG P V + GI S+ G G Y Sbjct: 479 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY-GF 537 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I + Sbjct: 538 YTHVFRLKKWIQKVIDQ 554 >3NXP-A nrPDB Length = 424 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 65/257 (25%), Positives = 106/257 (41%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 166 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 225 Query: 82 VVLGAHNLSRREPT-RQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ +++I+ Y+ NL DI +++L + + L Sbjct: 226 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 285 Query: 139 PAQ---GRRLGNGVQCLAMGWGLLGRN------RGIASVLQELNVTVVTS-LCRRSNVCT 188 P + L G + GWG L +G SVLQ +N+ +V +C+ S Sbjct: 286 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 345 Query: 189 LV-----------RGRQAGVCFGDSGSPLVCNGLIH------GIASFVRGGCASGLYPDA 231 + G++ C GDSG P V + GI S+ G G Y Sbjct: 346 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY-GF 404 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I + Sbjct: 405 YTHVFRLKKWIQKVIDQ 421 >1ETT-H nrPDB Length = 259 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 66/257 (25%), Positives = 107/257 (41%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G+ A P+ V L + CGA+LI+ +V++AAHC+ N V + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 82 VVLGAHNLSRRE-PTRQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ + +I+ Y+ NL DI +L+L ++ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 139 PAQ---GRRLGNGVQCLAMGWGLLGRNRGIA------SVLQELNVTVVTS-LCRRSNVCT 188 P + + L G + GWG + SVLQ +N+ +V +C+ S Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 189 LV-----------RGRQAGVCFGDSGSPLVCNGLIH------GIASFVRGGCASGLYPDA 231 + G++ C GDSG P V + GI S+ G G Y Sbjct: 181 ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKY-GF 239 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I R Sbjct: 240 YTHVFRLKKWIQKVIDR 256 >3K65-B nrPDB Length = 308 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 64/263 (24%), Positives = 108/263 (41%), Gaps = 39/263 (14%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANV 75 + + IV G A P+ V L + CGA+LI+ +V++AAHC+ N Sbjct: 44 SYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNF 103 Query: 76 NVRAVRVVLGAHNLSRREPT-RQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINAN 132 + V +G H+ +R E ++ +++I+ Y+ NL DI +++L + Sbjct: 104 TENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDY 163 Query: 133 VQVAQLPAQ---GRRLGNGVQCLAMGWGLLGRN------RGIASVLQELNVTVVTS-LCR 182 + LP + L G + GWG L +G SVLQ +N+ +V +C+ Sbjct: 164 IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCK 223 Query: 183 RSNVCTLV-----------RGRQAGVCFGDSGSPLVCNGLIH------GIASFVRGGCAS 225 S + G++ C GD+G P V + GI S+ G Sbjct: 224 DSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRD 283 Query: 226 GLYPDAFAPVAQFVNWIDSIIQR 248 G Y + V + WI +I + Sbjct: 284 GKY-GFYTHVFRLKKWIQKVIDQ 305 >4FXG-H nrPDB Length = 242 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 59/242 (24%), Positives = 98/242 (40%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I GG++A+P +P+ V + GG L+ N+V++AAH V A + + L Sbjct: 1 IYGGQKAKPGDFPWQV--LILGGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 90 SRREP-TRQVFAVQRIFENGYD-PVNLLNDIVILQLNGSATINANVQVAQLPAQGRR--L 145 R P Q ++ GY NDI +++LN IN+N+ LP + + Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-----TSLCRR----------SNVCTLV 190 A GWGL R +A L +++ +V T+ + + +C + Sbjct: 119 RTDDIGTASGWGLTQRGF-LARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 177 Query: 191 RGRQAGVCFGDSGSPLVC------NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GD+G LV + GI S+ C + V ++ WI++ Sbjct: 178 ESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIEN 237 Query: 245 II 246 II Sbjct: 238 II 239 >5TO3-B nrPDB Length = 409 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 65/257 (25%), Positives = 105/257 (40%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 82 VVLGAHNLSRREPT-RQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ +++I+ Y+ NL DI +++L + + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 139 PAQ---GRRLGNGVQCLAMGWGLLGRN------RGIASVLQELNVTVVT-SLCRRSNVCT 188 P + L G + GWG L +G SVLQ +N+ +V +C+ S Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 189 LV-----------RGRQAGVCFGDSGSPLVCNGLIH------GIASFVRGGCASGLYPDA 231 + G++ C GDSG P V + GI S G G Y Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKY-GF 239 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I + Sbjct: 240 YTHVFRLKKWIQKVIDQ 256 >4BXW-A nrPDB Length = 423 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 62/247 (25%), Positives = 102/247 (41%), Gaps = 31/247 (12%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IV G + P+ +L + G FCG T+++P +V++AAHC+ + VV+G + Sbjct: 170 IVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCIN--ETETISVVVGEID 227 Query: 89 LSRREPTRQVFAVQRIFEN----------GYDPVNLLNDIVILQLNGSATINANVQVAQL 138 SR E T + +V +I+ + +D DI I+Q+ + NV A L Sbjct: 228 KSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACL 286 Query: 139 PA---QGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN--------V 186 P + L + G+G + + L+ L V V C S+ Sbjct: 287 PTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNMF 346 Query: 187 CTLVRGRQAGVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C C GDSG P I GI S G +G Y + + +++F+ WI Sbjct: 347 CAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEGCARNGKYGN-YTKLSKFIPWI 405 Query: 243 DSIIQRS 249 I+++ Sbjct: 406 KRIMRQK 412 >1BDA-A nrPDB Length = 265 Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 62/240 (25%), Positives = 96/240 (40%), Gaps = 41/240 (17%) Query: 39 HAWPFMVSLQLR---GGHF-CGATLIAPNFVMSAAHCVAN-VNVRAVRVVLGAHNLSRRE 93 H W + + R G F CG LI+ +++SAAHC + V+LG Sbjct: 25 HPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPG 84 Query: 94 PTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINAN----VQVAQLPAQGRRLGNG 148 Q F V++ I +D NDI +LQL ++ A V+ LP +L + Sbjct: 85 EEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDW 144 Query: 149 VQCLAMGWGLLGRNRGIASVLQE--------------------LNVTVVTSLCRRSNVCT 188 +C G+ G++ ++ E LN TV ++ + T Sbjct: 145 TECELSGY---GKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGD--T 199 Query: 189 LVRGRQAGV---CFGDSGSPLVC--NGLIHGIASFVRG-GCASGLYPDAFAPVAQFVNWI 242 G QA + C GDSG PLVC +G + + G GC P + V +++WI Sbjct: 200 RSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWI 259 >2OLG-A nrPDB Length = 278 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 63/274 (22%), Positives = 113/274 (41%), Gaps = 46/274 (16%) Query: 17 PALL---LGGTALASEIVGGRRARPHAWPFMVSLQLRGGH-----FCGATLIAPNFVMSA 68 P LL G A +I+ G P +P+ + + CG +LI ++++A Sbjct: 7 PELLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTA 66 Query: 69 AHCVANVNVRAV----RVVLGAHNLSRRE----------PTRQV-FAVQRIFENGYDPVN 113 AHCVA +R V +V LG N + P + + ++ ++ D V+ Sbjct: 67 AHCVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHP-DYVD 125 Query: 114 ----LLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVL 169 +DI +++LN ++ LP + G + +GWG + +++ Sbjct: 126 GSKDRYHDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQ-YSTIK 184 Query: 170 QELNVTVV-TSLCRRSNVCTLVRGRQAGVCF----------GDSGSPLVCNG-----LIH 213 Q+L V VV C ++ VR R + +C GDSG PL+ + Sbjct: 185 QKLAVPVVHAEQCAKTFGAAGVRVRSSQLCAGGEKAKDSCGGDSGGPLLAERANQQFFLE 244 Query: 214 GIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G+ SF C + +P + V ++ +WI+ I+ Sbjct: 245 GLVSF-GATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >2OCV-B nrPDB Length = 259 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 65/257 (25%), Positives = 105/257 (40%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 82 VVLGAHNLSRREPT-RQVFAVQRIFEN-GYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ +++I+ + Y+ NL DI +L+L + + L Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 139 PAQ---GRRLGNGVQCLAMGWGLLGR------NRGIASVLQELNVTVVTS-LCRRSNVCT 188 P + L G + GWG L N SVLQ +N+ +V +C+ S Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 189 LVRG-----------RQAGVCFGDSGSPLVCNGLIH------GIASFVRGGCASGLYPDA 231 + ++ C GDSG P V + GI S+ G G Y Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKY-GF 239 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I + Sbjct: 240 YTHVFRLKAWIQKVIDQ 256 >4KKD-A nrPDB Length = 433 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 68/291 (23%), Positives = 113/291 (38%), Gaps = 55/291 (18%) Query: 3 LGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGH-------FC 55 LGR L C P+ L +L I+GGR A P +P+ + + F Sbjct: 130 LGRSLPTCLPECGQPSRSL--PSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFG 187 Query: 56 GATLIAPNFVMSAAH---------CVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFE 106 L++ +++++AAH V V+ V V LG H++ + A + + Sbjct: 188 SGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLH 247 Query: 107 NGYDPVNLLNDIVILQLNGSATINANVQVAQLP-AQGRRLGNGVQCLAMGWGLLGRN--- 162 ++ N +DI ++QL + +V LP + + L GWG+ N Sbjct: 248 PDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTV 307 Query: 163 --------RGIASVLQELNVTVV------TSLCRRSNVCTLVR-----GRQAG---VCFG 200 R ++ VLQ + + VV TS RS ++ G G C G Sbjct: 308 DEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLG 367 Query: 201 DSGSPLVC------NGLIHGIASFVRGG---CASGLYPDAFAPVAQFVNWI 242 DSG V ++ G+ S+ GG C S + V+ +V+W+ Sbjct: 368 DSGEAFVIFDDLSQRWVVQGLVSW--GGPEECGSKQVYGVYTKVSNYVDWV 416 >3I77-A nrPDB Length = 230 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 67/234 (28%), Positives = 100/234 (42%), Gaps = 28/234 (11%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAH 87 +VGG RA +PFMV L FCG L A + V++AAHCV+ N ++ G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 88 NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINA-NVQVAQLPAQGRRLG 146 +L + V + + + G+ D +++L + IN +++A A + Sbjct: 61 DLQSSSAVK-VRSTKVLQAPGFTKETYGKDWALIKL--AQPINQPTLKIATTTAYNQ--- 114 Query: 147 NGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSNVCTLVRGRQ--AG------- 196 G +A GWG L + NV V+ + CR S+ LV AG Sbjct: 115 -GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTGGV 172 Query: 197 -VCFGDSGSPLV----CNGLIH-GIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG P+ + I GI S+ GCA YP + V+ F + I S Sbjct: 173 DTCQGDSGGPMFRKDNADEWIQVGIVSWGY-GCARPGYPGVYTEVSTFASAIAS 225 >2KAI-A nrPDB Length = 80 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GGR ++ P+ V++ CG L+ P +V++AAHC N N V LG HNL Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHC-KNDN---YEVWLGRHNL 56 Query: 90 SRREPTRQVFAVQRIF 105 E T Q F V F Sbjct: 57 FENENTAQFFGVTADF 72 >3BEU-A nrPDB Length = 224 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 61/232 (26%), Positives = 97/232 (41%), Gaps = 30/232 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 +VGG RA +PFMV L + CG L A + V++AAHCV+ N ++ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINA-NVQVAQLPAQGRRLGN 147 L + V + + + G+ D +++L + IN +++A A Sbjct: 57 LQSSSAVK-VRSTKVLQAPGFTKETYGKDWALIKL--AQPINQPTLKIATTTA----YNQ 109 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN---------VCTLVRGRQAGV 197 G +A GWG L + NV V+ + CR S+ +C +Q Sbjct: 110 GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDT 168 Query: 198 CFGDSGSPLV----CNGLIH-GIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG P+ + + GI S+ G G Y + V+ F + I S Sbjct: 169 CQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKY-GVYTEVSTFASAIAS 219 >1AKS-B nrPDB Length = 98 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 23/49 (46%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG P+VCNG + GI S+ GCA P + V +VNWI I Sbjct: 48 CQGDSGGPVVCNGQLQGIVSWGY-GCAQKNKPGVYTKVCNYVNWIQQTI 95 >4IW4-E nrPDB Length = 279 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 60/264 (22%), Positives = 103/264 (39%), Gaps = 53/264 (20%) Query: 30 IVGGRRARPHAWPFMVSLQLRG-------GHFCGATLIAPNFVMSAAH---------CVA 73 I+GGR A P +P+ + + F L++ +++++AAH V Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 74 NVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANV 133 V+ V V LG H++ + A + + ++ N +DI ++QL + +V Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 134 QVAQLP-AQGRRLGNGVQCLAMGWGLLGRN-----------RGIASVLQELNVTVV---- 177 LP + + L GWG+ N R ++ VLQ + + VV Sbjct: 121 MPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAE 180 Query: 178 --TSLCRRSNVCTLVR-----GRQAG---VCFGDSGSPLVC------NGLIHGIASFVRG 221 TS RS ++ G G C GDSG V ++ G+ S+ G Sbjct: 181 CKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSW--G 238 Query: 222 G---CASGLYPDAFAPVAQFVNWI 242 G C S + V+ +V+W+ Sbjct: 239 GPEECGSKQVYGVYTKVSNYVDWV 262 >1BBR-H nrPDB Length = 150 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 14/142 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G+ A P+ V L + CGA+LI+ +V++AAHC+ N V + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 82 VVLGAHNLSRRE-PTRQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ + +I+ Y+ NL DI +L+L ++ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 139 PAQ---GRRLGNGVQCLAMGWG 157 P + + L G + GWG Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWG 142 >1EPT-B nrPDB Length = 82 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 3/79 (3%) Query: 80 VRVVLGAHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQL 138 ++V LG HN+ E Q +I + ++ L NDI++++L+ AT+N+ V L Sbjct: 3 IQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSL 62 Query: 139 PAQGRRLGNGVQCLAMGWG 157 P G +CL GWG Sbjct: 63 PRSCA--AAGTECLISGWG 79 >2FMJ-A nrPDB Length = 222 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 64/232 (27%), Positives = 99/232 (42%), Gaps = 32/232 (13%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 +VGG RA +PFMV L + CG L A + V++AAHCV+ N ++ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINA-NVQVAQLPAQGRRLGN 147 L + V + + + GY+ D +++L + IN +++A A + Sbjct: 57 LQSSSAVK-VRSTKVLQAPGYNGTG--KDWALIKL--AQPINQPTLKIATTTAYNQ---- 107 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSNVCTLVRGRQ--AG-------V 197 G +A GWG L + NV V+ + CR + LV + AG Sbjct: 108 GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVDT 166 Query: 198 CFGDSGSPLV----CNGLIH-GIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG P+ + I GI S+ G G Y + V+ F + I S Sbjct: 167 CQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKY-GVYTEVSTFASAIAS 217 >1RIW-B nrPDB Length = 147 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 12/131 (9%) Query: 41 WPFMVSLQLRGGHFCGATLIAPNFVMSAAHCV------ANVNVRAVRVVLGAHNLSRREP 94 W M+ + CGA+LI+ +V++AAHC+ N + V +G H+ +R E Sbjct: 14 WQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYER 73 Query: 95 T-RQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINANVQVAQLPAQ---GRRLGNG 148 ++ +++I+ Y+ NL DI +++L + + LP + L G Sbjct: 74 NIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAG 133 Query: 149 VQCLAMGWGLL 159 + GWG L Sbjct: 134 YKGRVTGWGNL 144 >3RU4-E nrPDB Length = 96 Score = 36.2 bits (82), Expect = 0.016, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 5/53 (9%) Query: 198 CFGDSGSPLVC--NG--LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG PLVC NG + GI S+ C++ P +A V VNW+ + Sbjct: 42 CMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTST-PGVYARVTALVNWVQQTL 93 >2JET-C nrPDB Length = 99 Score = 35.0 bits (79), Expect = 0.033, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 12/90 (13%) Query: 169 LQELNVTVVTSL-CRRS------NVCTLVRGRQAGVCFGDSGSPLVCNG----LIHGIAS 217 LQ+ + +V+ C++S +V T C GDSG PLVC + GI S Sbjct: 9 LQQAALPIVSEADCKKSWGSKITDVMTCAGASGVDSCMGDSGGPLVCQKDGVWTLAGIVS 68 Query: 218 FVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 + G C++ P ++ V + W+ I++ Sbjct: 69 WGSGVCSTST-PGVYSRVTALMPWVQQILE 97 >1P3E-A nrPDB Length = 215 Score = 33.5 bits (75), Expect = 0.099, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 18/29 (62%) Query: 51 GGHFCGATLIAPNFVMSAAHCVANVNVRA 79 GG C TLIAPN +++ HCV N R+ Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRS 56 >2HNT-C nrPDB Length = 70 Score = 30.8 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 8/70 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 82 VVLGAHNLSR 91 V +G H+ +R Sbjct: 61 VRIGKHSRTR 70 >2HNT-F nrPDB Length = 105 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 19/103 (18%) Query: 164 GIASVLQELNVTVVTS-LCRRSNVCTLV-----------RGRQAGVCFGDSGSPLVCNGL 211 G SVLQ +N+ +V +C+ S + G++ C GDSG P V Sbjct: 1 GQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSP 60 Query: 212 IH------GIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 + GI S+ G G Y + V + WI +I + Sbjct: 61 FNNRWYQMGIVSWGEGCDRDGKY-GFYTHVFRLKKWIQKVIDQ 102 >1BBR-E nrPDB Length = 109 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 19/100 (19%) Query: 167 SVLQELNVTVVTS-LCRRSNVCTLV-----------RGRQAGVCFGDSGSPLVCNGLIH- 213 SVLQ +N+ +V +C+ S + G++ C GDSG P V + Sbjct: 8 SVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNN 67 Query: 214 -----GIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GI S+ G G Y + V + WI +I R Sbjct: 68 RWYQMGIVSWGEGCDRDGKY-GFYTHVFRLKKWIQKVIDR 106 >3F1S-B nrPDB Length = 283 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 42 PFMVSL-QLRGGHFCGATLIAPNFVMSAAHC 71 P+ V L G FCG +I NFV++ A C Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC 95 >3H5C-B nrPDB Length = 317 Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 42 PFMVSL-QLRGGHFCGATLIAPNFVMSAAHC 71 P+ V L G FCG +I NFV++ A C Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC 136 >6MHY-A nrPDB Length = 440 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 9/58 (15%) Query: 189 LVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 L+ G A +GD S VCN + GC + Y +AF P++ W+ II Sbjct: 35 LILGTAADFVWGDEQSDFVCNTQ--------QPGCENVCYDEAF-PISHIRLWVLQII 83 >5O0W-A nrPDB Length = 387 Score = 26.9 bits (58), Expect = 9.2, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 11/84 (13%) Query: 9 CLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVM-- 66 C + V P +++ GT +I +R H W +VS R G L+ PN V+ Sbjct: 191 CGLVPIVEPEVMIDGT---HDIETCQRVSQHVWAEVVSALHRHGVVWEGCLLKPNMVVPG 247 Query: 67 ------SAAHCVANVNVRAVRVVL 84 + A VA V+ + VL Sbjct: 248 AESGQTATAEQVAEYTVKTLARVL 271 >1VA0-A nrPDB Length = 239 Score = 26.9 bits (58), Expect = 9.2, Method: Compositional matrix adjust. Identities = 19/40 (47%), Positives = 20/40 (50%), Gaps = 3/40 (7%) Query: 202 SGSPLVCNGLIHGIASFVRGGCASGLYPD--AFAPVAQFV 239 SG PL GL HG A+ V G G YPD FA V V Sbjct: 118 SGLPLTHRGLAHGFAA-VSGVLEGGGYPDLRPFARVPTLV 156 >1F2J-A nrPDB Length = 370 Score = 26.9 bits (58), Expect = 9.2, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 9 CLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSA 68 C + V P +++ GT +I +R H W +VS R G L+ PN V+ Sbjct: 190 CGLVPIVEPEVMIDGT---HDIETCQRVSQHVWSEVVSALHRHGVVWEGCLLKPNMVVPG 246 Query: 69 AH 70 A Sbjct: 247 AE 248 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1PPF-E nrPDB 305 2e-83 1FUJ-A nrPDB 293 4e-80 4AN7-A nrPDB 289 1e-78 1UTJ-A nrPDB 288 1e-78 4WWY-A nrPDB 285 1e-77 5FXL-A nrPDB 285 2e-77 1F7Z-A nrPDB 284 2e-77 1A0J-A nrPDB 284 2e-77 5C67-A nrPDB 284 2e-77 4DUR-A nrPDB 280 4e-76 1SGF-G nrPDB 276 8e-75 1EUF-A nrPDB 273 5e-74 5TJX-A nrPDB 272 1e-73 5UGG-A nrPDB 271 2e-73 1FI8-A nrPDB 271 3e-73 3E0N-B nrPDB 270 4e-73 1FXY-A nrPDB 270 4e-73 6I44-A nrPDB 270 5e-73 3T2N-A nrPDB 268 1e-72 4NFE-A nrPDB 267 4e-72 1SPJ-A nrPDB 266 6e-72 3W94-A nrPDB 265 2e-71 2TLD-E nrPDB 263 4e-71 5GVT-A nrPDB 263 7e-71 2EEK-A nrPDB 262 1e-70 4Q7Y-A nrPDB 261 2e-70 1P57-B nrPDB 260 4e-70 4DGJ-A nrPDB 260 5e-70 2F83-A nrPDB 260 5e-70 4GSO-A nrPDB 260 6e-70 1IAU-A nrPDB 259 7e-70 1AE5-A nrPDB 258 1e-69 1NPM-A nrPDB 258 2e-69 3QUM-P nrPDB 257 3e-69 3BSQ-A nrPDB 257 4e-69 2AIQ-A nrPDB 257 5e-69 1FDP-A nrPDB 256 7e-69 1BRU-P nrPDB 256 7e-69 1EKB-B nrPDB 256 8e-69 1NN6-A nrPDB 256 9e-69 1AO5-A nrPDB 255 2e-68 4KKD-A nrPDB 255 2e-68 3DFJ-A nrPDB 255 2e-68 4Z6A-H nrPDB 254 3e-68 5MS3-A nrPDB 254 4e-68 1OP0-A nrPDB 253 4e-68 5FCR-A nrPDB 252 1e-67 5ZFH-A nrPDB 252 1e-67 1X7A-C nrPDB 252 1e-67 1TON-A nrPDB 252 2e-67 2CGA-A nrPDB 252 2e-67 3LC3-A nrPDB 250 3e-67 3S69-A nrPDB 250 3e-67 2F91-A nrPDB 250 4e-67 4E7N-A nrPDB 250 4e-67 1GVZ-A nrPDB 250 6e-67 1KIG-H nrPDB 249 7e-67 1ORF-A nrPDB 248 1e-66 3G01-A nrPDB 248 2e-66 1BQY-A nrPDB 247 3e-66 4H4F-A nrPDB 247 3e-66 4MPW-A nrPDB 247 3e-66 3P8G-A nrPDB 247 4e-66 1C5M-D nrPDB 247 4e-66 6AOD-C nrPDB 247 4e-66 2V35-A nrPDB 247 4e-66 2PSX-A nrPDB 247 5e-66 1SGF-A nrPDB 247 5e-66 3TK9-A nrPDB 246 9e-66 3S9B-A nrPDB 245 1e-65 3K65-B nrPDB 245 1e-65 1MKW-K nrPDB 245 2e-65 2BDH-A nrPDB 245 2e-65 1PYT-D nrPDB 244 2e-65 6QHB-A nrPDB 244 3e-65 4IGD-A nrPDB 243 5e-65 2OQ5-A nrPDB 243 5e-65 3NXP-A nrPDB 243 6e-65 1LTO-A nrPDB 243 6e-65 1Q3X-A nrPDB 243 8e-65 1YC0-A nrPDB 241 3e-64 4NZQ-A nrPDB 240 4e-64 1ZJK-A nrPDB 239 8e-64 3RP2-A nrPDB 239 1e-63 1FIZ-A nrPDB 239 1e-63 1MZD-A nrPDB 239 1e-63 2RDL-A nrPDB 238 2e-63 1FIW-A nrPDB 235 1e-62 1KYN-A nrPDB 235 1e-62 1ELT-A nrPDB 235 1e-62 2ZKS-A nrPDB 234 3e-62 2XRC-A nrPDB 233 4e-62 3F6U-H nrPDB 233 5e-62 4XDE-A nrPDB 233 6e-62 1ETT-H nrPDB 233 7e-62 2OCV-B nrPDB 233 7e-62 2R0L-A nrPDB 232 9e-62 1VR1-H nrPDB 232 2e-61 2XXL-A nrPDB 231 3e-61 1FON-A nrPDB 228 2e-60 5LHN-A nrPDB 228 3e-60 5O32-I nrPDB 228 3e-60 1AZZ-A nrPDB 227 5e-60 1BDA-A nrPDB 227 6e-60 4FXG-H nrPDB 225 2e-59 1SC8-U nrPDB 225 2e-59 1A5I-A nrPDB 224 3e-59 4IW4-E nrPDB 224 4e-59 1EQ9-A nrPDB 219 1e-57 5TO3-B nrPDB 219 1e-57 5XRF-A nrPDB 218 1e-57 4BXW-A nrPDB 216 1e-56 1YM0-A nrPDB 214 3e-56 4DJZ-B nrPDB 212 1e-55 5LPF-A nrPDB 212 1e-55 2OLG-A nrPDB 211 3e-55 6BQM-A nrPDB 209 1e-54 4LK4-A nrPDB 208 1e-54 5KWM-A nrPDB 204 4e-53 2B9L-A nrPDB 201 3e-52 1PQ7-A nrPDB 198 1e-51 3I77-A nrPDB 195 1e-50 2ASU-B nrPDB 195 2e-50 1SI5-H nrPDB 194 4e-50 3BEU-A nrPDB 192 2e-49 3H7T-A nrPDB 189 1e-48 2FMJ-A nrPDB 182 1e-46 1M9U-A nrPDB 182 2e-46 3H7O-A nrPDB 178 2e-45 2HLC-A nrPDB 178 3e-45 5XW8-A nrPDB 174 3e-44 2PKA-B nrPDB 174 3e-44 3VGC-B nrPDB 166 8e-42 2JET-B nrPDB 160 6e-40 1BBR-H nrPDB 152 1e-37 1AKS-B nrPDB 123 1e-28 2KAI-A nrPDB 114 3e-26 1EPT-B nrPDB 104 3e-23 Sequences not found previously or not previously below threshold: 1GPZ-A nrPDB 200 7e-52 1MD7-A nrPDB 199 1e-51 1ELV-A nrPDB 199 1e-51 4J1Y-A nrPDB 193 9e-50 2QY0-B nrPDB 189 1e-48 5UBM-A nrPDB 187 5e-48 4WJG-C nrPDB 156 1e-38 1RIW-B nrPDB 154 4e-38 4F4O-C nrPDB 151 3e-37 4X0L-C nrPDB 150 6e-37 2WIN-I nrPDB 110 8e-25 1DLE-A nrPDB 107 6e-24 2I6S-A nrPDB 105 2e-23 2OK5-A nrPDB 105 2e-23 3F1S-B nrPDB 93 1e-19 2HNT-F nrPDB 93 1e-19 1BBR-E nrPDB 92 2e-19 3H5C-B nrPDB 90 8e-19 3RU4-E nrPDB 88 5e-18 2JET-C nrPDB 85 3e-17 2HNT-C nrPDB 83 1e-16 2HNT-E nrPDB 76 1e-14 1P3E-A nrPDB 50 8e-07 1DUE-A nrPDB 37 0.008 2SFA-A nrPDB 36 0.015 2EA3-A nrPDB 35 0.035 2PFE-A nrPDB 34 0.047 2SGA-A nrPDB 34 0.051 2OUA-A nrPDB 34 0.068 4FVB-A nrPDB 31 0.60 3W95-A nrPDB 31 0.60 3FD5-A nrPDB 31 0.73 4NCX-A nrPDB 31 0.85 5OJX-A nrPDB 29 1.8 2HRV-A nrPDB 29 2.1 2M5T-A nrPDB 29 2.5 3LT3-A nrPDB 29 3.2 5XIG-A nrPDB 28 3.3 4NWK-A nrPDB 28 4.5 5XIP-A nrPDB 28 4.5 5JYK-A nrPDB 28 4.6 4FXG-G nrPDB 28 4.7 3TVJ-A nrPDB 28 4.7 5ILA-A nrPDB 27 6.1 1HPG-A nrPDB 27 9.2 >1PPF-E nrPDB Length = 218 Score = 305 bits (781), Expect = 2e-83, Method: Composition-based stats. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV Sbjct: 61 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 120 Query: 150 QCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCN 209 QCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCN Sbjct: 121 QCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCN 180 Query: 210 GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ Sbjct: 181 GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1FUJ-A nrPDB Length = 221 Score = 293 bits (751), Expect = 4e-80, Method: Composition-based stats. Identities = 121/221 (54%), Positives = 161/221 (72%), Gaps = 3/221 (1%) Query: 30 IVGGRRARPHAWPFMVSLQLRG---GHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 IVGG A+PH+ P+M SLQ+RG HFCG TLI P+FV++AAHC+ ++ R V VVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 87 HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 HN+ +EPT+Q F+V ++F N YD N LNDI+++QL+ A ++A+V QLP Q + + Sbjct: 61 HNVRTQEPTQQHFSVAQVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPVP 120 Query: 147 NGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPL 206 +G QCLAMGWG +G + A VLQELNVTVVT CR N+CT V R+AG+CFGDSG PL Sbjct: 121 HGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPL 180 Query: 207 VCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 +C+G+I GI SFV GCA+ L+PD F VA +V+WI S ++ Sbjct: 181 ICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >4AN7-A nrPDB Length = 231 Score = 289 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 76/233 (32%), Positives = 110/233 (47%), Gaps = 19/233 (8%) Query: 28 SEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 +IVGG ++ P+ VSL G HFCG +LI +V+SAAHC + ++V LG H Sbjct: 7 DKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGEH 61 Query: 88 NLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 N+ E Q +I ++ L NDI++++L+ AT+N+ V LP Sbjct: 62 NIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA--A 119 Query: 147 NGVQCLAMGWGLLGRNRG-IASVLQELNVTVVTSLCRRS---------NVCTLVRGRQAG 196 G +CL GWG + S+LQ L V++ +S +C Sbjct: 120 AGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKD 179 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 C GDSG P+VCNG + GI S+ GCA P + V +VNWI I + Sbjct: 180 SCQGDSGGPVVCNGQLQGIVSWGY-GCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >1UTJ-A nrPDB Length = 242 Score = 288 bits (738), Expect = 1e-78, Method: Composition-based stats. Identities = 83/243 (34%), Positives = 119/243 (48%), Gaps = 21/243 (8%) Query: 19 LLLGGTALA---SEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV 75 +LL G A A +IVGG +P++ P VSL G HFCG +L+ N+V+SAAHC + Sbjct: 7 VLLIGAAFATEDDKIVGGYECKPYSQPHQVSL-NSGYHFCGGSLVNENWVVSAAHCYKSR 65 Query: 76 NVRAVRVVLGAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQ 134 V V LG HN+ E + Q + R+ Y N+ NDI++++L+ AT+N VQ Sbjct: 66 ----VEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQ 121 Query: 135 VAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRS--------N 185 LP G C GWG + ++ LQ LN+ +++ S C S Sbjct: 122 PVALPTSCA--PAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGMITNAM 179 Query: 186 VCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSI 245 C C GDSG P+VCNG + G+ S+ GCA P +A V F +W+ S Sbjct: 180 FCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGY-GCAEPGNPGVYAKVCIFNDWLTST 238 Query: 246 IQR 248 + Sbjct: 239 MAS 241 >4WWY-A nrPDB Length = 224 Score = 285 bits (731), Expect = 1e-77, Method: Composition-based stats. Identities = 75/232 (32%), Positives = 106/232 (45%), Gaps = 19/232 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG ++ P+ VSL G HFCG +LI +V+SA HC + ++V LG HN+ Sbjct: 1 IVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKSR----IQVRLGEHNI 55 Query: 90 SRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E Q +I YD L NDI++++L+ A INA+V LP G Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTA--PPATG 113 Query: 149 VQCLAMGWGLLGRNR-GIASVLQELNVTVVT-SLCRRS--------NVCTLVRGRQAGVC 198 +CL GWG + LQ L+ V++ + C S C C Sbjct: 114 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSC 173 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 DSG P+VCNG + G+ S+ GCA P + V +V WI + I + Sbjct: 174 QRDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAANS 224 >5FXL-A nrPDB Length = 246 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 108/233 (46%), Gaps = 19/233 (8%) Query: 28 SEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 +IVGG + P+ VSL G HFCG +LI +V+SAAHC + ++V LG Sbjct: 22 DKIVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKS----GIQVRLGED 76 Query: 88 NLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 N++ E Q + + I Y+ L NDI++++L +A++N+ V LP Sbjct: 77 NINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS-- 134 Query: 147 NGVQCLAMGWGLLGRNR-GIASVLQELNVTVVTSLCRRS---------NVCTLVRGRQAG 196 G QCL GWG + VL+ L +++ +S C Sbjct: 135 AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKD 194 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 C GDSG P+VC+G + GI S+ GCA P + V +V+WI I + Sbjct: 195 SCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >1F7Z-A nrPDB Length = 233 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 76/231 (32%), Positives = 109/231 (47%), Gaps = 19/231 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + ++ P+ VSL G HFCG +LI +V+SAAHC + ++V LG HN+ Sbjct: 11 IVGGYTCQENSVPYQVSL-NSGYHFCGGSLINDQWVVSAAHCYKSR----IQVRLGEHNI 65 Query: 90 SRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 + E Q +I +D L NDI++++L+ +NA V LP+ G Sbjct: 66 NVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCA--PAG 123 Query: 149 VQCLAMGWGLL-GRNRGIASVLQELNVTVV-TSLCRRS--------NVCTLVRGRQAGVC 198 QCL GWG +LQ L+ ++ + C S VC C Sbjct: 124 TQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSC 183 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GDSG P+VCNG + GI S+ GCA P + V +V+WI I + Sbjct: 184 QGDSGGPVVCNGELQGIVSWGY-GCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >1A0J-A nrPDB Length = 223 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 75/231 (32%), Positives = 117/231 (50%), Gaps = 19/231 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG R ++ + SLQ G HFCG +LI+ +V+SAAHC + ++V LG HN+ Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKSR----IQVRLGEHNI 55 Query: 90 SRREPTRQVF-AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 + E T Q +V+ I Y+ NL NDI++++L+ A++N+ V LP+ +G Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCAS--SG 113 Query: 149 VQCLAMGWGLLG-RNRGIASVLQELNVTVVTSLCRRS---------NVCTLVRGRQAGVC 198 +CL GWG L + L+ L++ +++S S C C Sbjct: 114 TRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSC 173 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GDSG P+VCNG + G+ S+ GCA P + V + +WI S + + Sbjct: 174 QGDSGGPVVCNGQLQGVVSWGY-GCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >5C67-A nrPDB Length = 224 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 74/232 (31%), Positives = 106/232 (45%), Gaps = 19/232 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG ++ P+ VSL G HFCG +LI+ +V+SAAHC ++V LG HN+ Sbjct: 1 IVGGYTCEENSLPYQVSL-NSGSHFCGGSLISEQWVVSAAHCYK----TRIQVRLGEHNI 55 Query: 90 SRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E Q +I Y+ L NDI++++L+ A INA V LP G Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTA--PPAAG 113 Query: 149 VQCLAMGWGLLGR-NRGIASVLQELNVTVVT-SLCR--------RSNVCTLVRGRQAGVC 198 +CL GWG L+ L+ V+T + C+ S C C Sbjct: 114 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 173 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 D+G P+VCNG + G+ S+ GCA P + V +V+WI I + Sbjct: 174 QRDAGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 224 >4DUR-A nrPDB Length = 791 Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats. Identities = 81/263 (30%), Positives = 121/263 (46%), Gaps = 29/263 (11%) Query: 9 CLFLACVLPALLLGGTALAS-----EIVGGRRARPHAWPFMVSLQLR-GGHFCGATLIAP 62 C C P+ G + +VGG A PH+WP+ VSL+ R G HFCG TLI+P Sbjct: 536 CDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISP 595 Query: 63 NFVMSAAHCVANVN-VRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVIL 121 +V++AAHC+ + +V+LGAH EP Q V R+F DI +L Sbjct: 596 EWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP-----TRKDIALL 650 Query: 122 QLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLC 181 +L+ A I V A LP+ + + +C GWG G A +L+E + V+ + Sbjct: 651 KLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG-AGLLKEAQLPVIENKV 709 Query: 182 RRSN-----------VCTLVRGRQAGVCFGDSGSPLVC----NGLIHGIASFVRGGCASG 226 +C C GDSG PLVC ++ G+ S+ GCA Sbjct: 710 CNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARP 768 Query: 227 LYPDAFAPVAQFVNWIDSIIQRS 249 P + V++FV WI+ +++ + Sbjct: 769 NKPGVYVRVSRFVTWIEGVMRNN 791 >1SGF-G nrPDB Length = 237 Score = 276 bits (706), Expect = 8e-75, Method: Composition-based stats. Identities = 65/242 (26%), Positives = 113/242 (46%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + ++ P+ V++ + CG L+ PN+V++AAHC +V LG +NL Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYD----DNYKVWLGKNNL 56 Query: 90 SRREPTRQVFAVQR-IFENGYDPV-----------NLLNDIVILQLNGSATINANVQVAQ 137 + EP+ Q V + I G++ + ND+++L+L+ A I V+ Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNR-GIASVLQELNVTVV-TSLCRRS--------NVC 187 LP + +L G CLA GWG + + L +N+ ++ C ++ +C Sbjct: 117 LPTEEPKL--GSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLC 174 Query: 188 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PL+C+G++ GI S+ C P + + +F +WI + Sbjct: 175 AGEMDGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMA 234 Query: 248 RS 249 ++ Sbjct: 235 KN 236 >1EUF-A nrPDB Length = 227 Score = 273 bits (699), Expect = 5e-74, Method: Composition-based stats. Identities = 80/234 (34%), Positives = 121/234 (51%), Gaps = 20/234 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GG A+PH+ P+M L + H CG L+ +FV++AAHC+ + ++ V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGS----SINVTLGA 56 Query: 87 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 HN+ RE T+QV V+R I Y+ L NDI++L+L A I V LP + Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEV 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT---------SLCRRSNVCTLVRGRQAG 196 G+ C GWG LG N LQE+++ V + + + +C ++ Sbjct: 117 KPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKN 176 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 GDSG PLVCNG+ GI S+ R G PD + ++ F++WI S ++R + Sbjct: 177 SFSGDSGGPLVCNGVAQGIVSYGRN---DGTTPDVYTRISSFLSWIHSTMRRYK 227 >5TJX-A nrPDB Length = 263 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 67/251 (26%), Positives = 112/251 (44%), Gaps = 24/251 (9%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRA- 79 T ++ IVGG + WP+ VSLQ++ H CG +LI +V++AAHC + ++ Sbjct: 10 TKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV 69 Query: 80 ---VRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVA 136 +L ++++ P Q+ + I Y +DI +++L + Sbjct: 70 WRIYSGILELSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPI 127 Query: 137 QLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRR---------SNV 186 LP++G C GWG I ++LQ++N+ +VT+ C++ V Sbjct: 128 SLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMV 187 Query: 187 CTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C + C GDSG PLVC + GI S+ GCA P + VA++++WI Sbjct: 188 CAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 246 Query: 243 DSIIQRSEDNP 253 Q S+ Sbjct: 247 LEKTQSSDGKA 257 >5UGG-A nrPDB Length = 251 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 79/256 (30%), Positives = 119/256 (46%), Gaps = 29/256 (11%) Query: 16 LPALLLGGTALAS-----EIVGGRRARPHAWPFMVSLQLR-GGHFCGATLIAPNFVMSAA 69 P+ G + +VGG A PH+WP+ VSL+ R G HFCG TLI+P +V++AA Sbjct: 3 APSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAA 62 Query: 70 HCVANVN-VRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSAT 128 HC+ + +V+LGAH EP Q V R+F DI +L+L+ A Sbjct: 63 HCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP-----TRKDIALLKLSSPAV 117 Query: 129 INANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSN--- 185 I V A LP+ + + +C GWG G A +L+E + V+ + Sbjct: 118 ITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG-AGLLKEAQLPVIENKVCNRYEFL 176 Query: 186 --------VCTLVRGRQAGVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFA 233 +C C GDSG PLVC ++ G+ S+ GCA P + Sbjct: 177 NGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYV 235 Query: 234 PVAQFVNWIDSIIQRS 249 V++FV WI+ +++ + Sbjct: 236 RVSRFVTWIEGVMRNN 251 >1FI8-A nrPDB Length = 228 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 75/235 (31%), Positives = 115/235 (48%), Gaps = 22/235 (9%) Query: 30 IVGGRRARPHAWPFMVSLQ----LRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG A+PH+ P+M LQ G CG LI +FV++AAHC + ++V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS----KIQVTLG 56 Query: 86 AHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AHN+ +E +Q+ V +I Y+ + NDI++L+L A ++ V+ LP + + Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSN----------VCTLVRGRQ 194 + G C GWG LG + LQE+ +TV S +C + Sbjct: 117 VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIK 176 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GDSG PLVC + GI S+ + G P AF V+ F++WI +++S Sbjct: 177 RASFRGDSGGPLVCKKVAAGIVSYGQN---DGSTPRAFTKVSTFLSWIKKTMKKS 228 >3E0N-B nrPDB Length = 271 Score = 270 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 70/260 (26%), Positives = 108/260 (41%), Gaps = 26/260 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVR-AVRVVLGAHN 88 I GG A WP+ VS+ G H CG +L++ +V+SAAHC + + + A V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 89 LSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 L +V ++ I Y DI +LQL+ T + ++ LPA N Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 148 GVQCLAMGWGLLGRNRGI--ASVLQELNVTVVT-SLC----------------RRSNVCT 188 G+ C GWG + + + LQ+L V +++ C + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCA 180 Query: 189 LVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG PL C + GI S+ C + P + + + +WI S Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYTLASSYASWIQS 239 Query: 245 IIQRSEDNPCPHPRDPDPAS 264 + + P ++ P S Sbjct: 240 KVTELQPRVVPQTQESQPDS 259 >1FXY-A nrPDB Length = 228 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 65/233 (27%), Positives = 97/233 (41%), Gaps = 17/233 (7%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IVGG + P+ L FCG T+++ ++++AAHC+ +V +G N Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKR--FKVRVGDRN 58 Query: 89 LSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 + E V V+ + N + DI +L+L T NV A LP Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTA--PPAT 116 Query: 148 GVQCLAMGWGLLGRNR-GIASVLQELNVTVVT-SLCRRS--------NVCTLVRGRQAGV 197 G +CL GWG + LQ L+ V++ + C S C Sbjct: 117 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDS 176 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 C GDSG P+VCNG + G+ S+ GCA P + V +V WI + I + Sbjct: 177 CQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAANS 228 >6I44-A nrPDB Length = 627 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 68/261 (26%), Positives = 116/261 (44%), Gaps = 24/261 (9%) Query: 14 CVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAH 70 C + T ++ IVGG ++ WP+ VSLQ++ H CG +LI +V++AAH Sbjct: 364 CNTGDNSVCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAH 423 Query: 71 CVANVNVRA-VRVVLG---AHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGS 126 C + ++ R+ G ++++ P Q+ + I Y +DI +++L Sbjct: 424 CFDGLPLQDVWRIYSGILQLSDITKDTPFSQIKEI--IIHQNYKVSEGNHDIALIKLQAP 481 Query: 127 ATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRR-- 183 + LP++G C GWG I ++LQ++N+ +VT+ C++ Sbjct: 482 LQYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRY 541 Query: 184 -------SNVCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAF 232 VC + C GD+G PLVC + GI S+ GCA P + Sbjct: 542 QDYKITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVY 600 Query: 233 APVAQFVNWIDSIIQRSEDNP 253 VA++++WI Q S+ Sbjct: 601 TKVAEYMDWILEKTQSSDGKA 621 >3T2N-A nrPDB Length = 372 Score = 268 bits (686), Expect = 1e-72, Method: Composition-based stats. Identities = 76/281 (27%), Positives = 113/281 (40%), Gaps = 33/281 (11%) Query: 4 GRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPN 63 GR LA + C L + IVGGR WP+ VSL+ G H CG +L++ + Sbjct: 98 GRFLAAICQDCGRRKLPV------DRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGD 151 Query: 64 FVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQ-RIFENGY------DPVNLLN 116 +V++AAHC N R + A +++ P VQ ++ GY + N Sbjct: 152 WVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSN 211 Query: 117 DIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTV 176 DI ++ L+ + +Q LPA G+ L +G C GWG A VLQE V + Sbjct: 212 DIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPI 271 Query: 177 VT-----------SLCRRSNVCTLVRGRQAGVCFGDSGSPLVCN--------GLIHGIAS 217 ++ + + C C GDSG P VC + GI S Sbjct: 272 ISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVS 331 Query: 218 FVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPR 258 + GCA P + V+ F WI I+ + + Sbjct: 332 WG-TGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQ 371 >4NFE-A nrPDB Length = 237 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 72/242 (29%), Positives = 112/242 (46%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ P+ V++ G CG L+ P +V++AAHC+ + +V LG HNL Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRHNL 56 Query: 90 SRREPTRQVFAVQRIFENG-YD-----------PVNLLNDIVILQLNGSATINANVQVAQ 137 E T Q V F + Y+ + +D+++L+L+ A I V+V Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNRGI-ASVLQELNVTVVTS-LCRRS--------NVC 187 LP Q L G C A GWG + + LQ +++ ++++ +C R+ +C Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLC 174 Query: 188 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 + C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 175 AGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIA 234 Query: 248 RS 249 + Sbjct: 235 AN 236 >1SPJ-A nrPDB Length = 238 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 65/244 (26%), Positives = 109/244 (44%), Gaps = 29/244 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ P+ +L CG L+ +V++AAHC++ ++ LG HNL Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCIS----DNYQLWLGRHNL 56 Query: 90 SRREPTRQVFAV-QRIFENGYD-----------PVNLLNDIVILQLNGSA-TINANVQVA 136 E T Q V + G++ + +D+++L+L A TI V+V Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 137 QLPAQGRRLGNGVQCLAMGWGLLGR-NRGIASVLQELNVTVV-TSLCRRS--------NV 186 +LP + + G CLA GWG + N LQ +++ ++ C+++ + Sbjct: 117 ELPTEEPEV--GSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFML 174 Query: 187 CTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C C GDSG PL+C+G++ G+ S+ C + P V +V WI+ I Sbjct: 175 CVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 234 Query: 247 QRSE 250 + Sbjct: 235 AENS 238 >3W94-A nrPDB Length = 235 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 75/234 (32%), Positives = 104/234 (44%), Gaps = 19/234 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVN--VRAVRVVLGAH 87 +VGG A AWP+MVSL RG H CGA+LI +++++AAHCV N ++ VLG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 88 NLSR-REPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 S Q+ V RI N Y+ DI ++ L V L ++ + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR---------SNVCTLVRGRQA 195 G +C GWG + +LQE V +V C+R S +C Sbjct: 121 PAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGGV 180 Query: 196 GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSI 245 C GDSG PL+C + G+ SF GC P A+A V+ F +WI Sbjct: 181 DSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTSWIAET 233 >2TLD-E nrPDB Length = 220 Score = 263 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 73/231 (31%), Positives = 109/231 (47%), Gaps = 22/231 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + P+ VSL G HFCG +LI +V+SAAHC + ++V LG N+ Sbjct: 1 IVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKS----GIQVRLGEDNI 55 Query: 90 SRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 + E Q + + I Y+ L NDI++++L +A++N+ V LP G Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS--AG 113 Query: 149 VQCLAMGWGLLGRNR-GIASVLQELNVTVVTSLCRRS---------NVCTLVRGRQAGVC 198 QCL GWG + VL+ L +++ +S C + G C Sbjct: 114 TQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGG--DSC 171 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GDSG P+VC+G + GI S+ GCA P + V +V+WI I + Sbjct: 172 QGDSGGPVVCSGKLQGIVSWGS-GCAK-NKPGVYTKVCNYVSWIKQTIASN 220 >5GVT-A nrPDB Length = 250 Score = 263 bits (672), Expect = 7e-71, Method: Composition-based stats. Identities = 60/245 (24%), Positives = 101/245 (41%), Gaps = 24/245 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG- 85 IVGG A WP+ VSLQ++ H CG ++I +V++AAHC + V + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 86 ---AHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 +++ P+ ++ + I Y DI +++L + LP++ Sbjct: 61 ILSLSEITKETPSSRIKEL--IIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKA 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRS---------NVCTLVRG 192 C GWG ++LQ+ + +V C++ +C + Sbjct: 119 DTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKE 178 Query: 193 RQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 C GDSG PLVC + GI S+ GCA P + V+++++WI Q Sbjct: 179 GGTDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKDQPGVYTKVSEYMDWILEKTQS 237 Query: 249 SEDNP 253 S+ Sbjct: 238 SDVRA 242 >2EEK-A nrPDB Length = 220 Score = 262 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 69/228 (30%), Positives = 107/228 (46%), Gaps = 18/228 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ VSL G HFCG +L++ ++V+SAAHC +V +RV LG H++ Sbjct: 1 IVGGYECTKHSQAHQVSL-NSGYHFCGGSLVSKDWVVSAAHCYKSV----LRVRLGEHHI 55 Query: 90 SRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E T Q + + Y N+ NDI++++L AT+N V LP + + Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECA--ADA 113 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVTS---------LCRRSNVCTLVRGRQAGVCF 199 C GWG + LQ L++ +++ + +S C C Sbjct: 114 TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQ 173 Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GDSG P+VCNG++ G+ S+ GCA +P +A V W+ + Sbjct: 174 GDSGGPVVCNGVLQGVVSWGY-GCAERDHPGVYAKVCVLSGWVRDTMA 220 >4Q7Y-A nrPDB Length = 250 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 89/245 (36%), Positives = 124/245 (50%), Gaps = 12/245 (4%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG PH+ P+M S++ G H CG L+ +V+SAAHC ++ ++R VVLGAH L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 90 SRREPTRQVFAVQRI-FENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG-N 147 S EPT+QVF + + Y P+ NDI +L+LNGSA + V + +LP + R Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRS--------NVCTLVRG-RQAGV 197 G +C GWG + + L E V V+ +C S +CT + G Sbjct: 121 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 180 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHP 257 C DSG PLVC HG+ SF C PD + V+ FV WI +++RS P P P Sbjct: 181 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLP 240 Query: 258 RDPDP 262 P Sbjct: 241 GTTRP 245 >1P57-B nrPDB Length = 255 Score = 260 bits (666), Expect = 4e-70, Method: Composition-based stats. Identities = 70/255 (27%), Positives = 105/255 (41%), Gaps = 27/255 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGGR WP+ VSL+ G H CG +L++ ++V++AAHC N R + A + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 90 SRREPTRQVFAVQ-RIFENGY------DPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 ++ P VQ ++ GY + NDI ++ L+ + +Q LPA G Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-----------SLCRRSNVCTLVR 191 + L +G C GWG A VLQE V +++ + + C Sbjct: 121 QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYP 180 Query: 192 GRQAGVCFGDSGSPLVCN--------GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWID 243 C GDSG P VC + GI S+ GCA P + V+ F WI Sbjct: 181 EGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYTKVSDFREWIF 239 Query: 244 SIIQRSEDNPCPHPR 258 I+ + + Sbjct: 240 QAIKTHSEASGMVTQ 254 >4DGJ-A nrPDB Length = 235 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 66/236 (27%), Positives = 104/236 (44%), Gaps = 19/236 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVN--VRAVRVVLGAH 87 IVGG A+ AWP++V L CGA+L++ ++++SAAHCV N +LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 88 NLSRREPTRQV--FAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 S + V + + Y+ NDI ++ L +Q LP + + Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL-CRR---------SNVCTLVRGRQA 195 G C GWG + A +LQE +V ++++ C++ + +C Sbjct: 121 PPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGI 180 Query: 196 GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PL+C + G+ SF CA P +A V++F WI S + Sbjct: 181 DSCQGDSGGPLMCQENNRWFLAGVTSFGYE-CALPNRPGVYARVSRFTEWIQSFLH 235 >2F83-A nrPDB Length = 625 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 66/238 (27%), Positives = 103/238 (43%), Gaps = 20/238 (8%) Query: 24 TALASEIVGGRRARPHAWPFMVSLQLRG---GHFCGATLIAPNFVMSAAHCVANV-NVRA 79 T + IVGG + WP+ V+L H CG ++I ++++AAHC V + + Sbjct: 382 TKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKI 441 Query: 80 VRVVLGAHNLSRREPTRQVFAV-QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQL 138 +RV G N S + F V + I + Y DI +L+L + + + L Sbjct: 442 LRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL 501 Query: 139 PAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRS---------NVCT 188 P++G R C GWG I + LQ+ + +VT+ C++ +C Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICA 561 Query: 189 LVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 R C GDSG PL C + GI S+ GCA P + V ++V+WI Sbjct: 562 GYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 618 >4GSO-A nrPDB Length = 232 Score = 260 bits (664), Expect = 6e-70, Method: Composition-based stats. Identities = 65/238 (27%), Positives = 103/238 (43%), Gaps = 19/238 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG + PF+ L G +FCG TLI +V++AAHC + ++ LG H+ Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHC----DSTNFQMQLGVHSK 55 Query: 90 SRREPTRQVF--AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 Q + I N L DI++++L+ + + ++ LP+ + Sbjct: 56 KVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSV-- 113 Query: 148 GVQCLAMGWGLLG-RNRGIASVLQELNVTVVT-SLCR--------RSNVCTLVRGRQAGV 197 G C MGWG + N V N+ +V +C+ ++ +C V Sbjct: 114 GSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDT 173 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 C GDSG PL+CNG GI S+ C G P + V + +WI I + D CP Sbjct: 174 CVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGNTDATCP 231 >1IAU-A nrPDB Length = 227 Score = 259 bits (663), Expect = 7e-70, Method: Composition-based stats. Identities = 80/233 (34%), Positives = 116/233 (49%), Gaps = 21/233 (9%) Query: 30 IVGGRRARPHAWPFMVSLQL---RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GG A+PH+ P+M L + + CG LI +FV++AAHC + ++ V LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS----SINVTLGA 56 Query: 87 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 HN+ +EPT+Q V+R I Y+P N NDI++LQL A VQ +LP+ ++ Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQV 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRS---------NVCTLVRGRQA 195 G C GWG + LQE+ +TV C +C + Sbjct: 117 KPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKK 176 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GDSG PLVCN + GI S+ R +G+ P A V+ FV+WI ++R Sbjct: 177 TSFKGDSGGPLVCNKVAQGIVSYGRN---NGMPPRACTKVSSFVHWIKKTMKR 226 >1AE5-A nrPDB Length = 225 Score = 258 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 104/230 (45%), Positives = 140/230 (60%), Gaps = 8/230 (3%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGGR+ARP +PF+ S+Q +G HFCG LI FVM+AA C + N VVLGA++L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 90 SRRE-PTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 RRE +RQ F++ + ENGYDP LND+++LQL+ A + ++V + LP Q + G Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSNVCTLVRGRQAGVCFGDSGSPLV 207 +C GWG ++ + +NVTV CR +NVCT V R+ G+C GD G+PLV Sbjct: 121 TRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV 180 Query: 208 CNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHP 257 C GL HG+ASF G C G PD F VA F +WID ++ +NP P P Sbjct: 181 CEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL----NNPGPGP 224 >1NPM-A nrPDB Length = 225 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 64/231 (27%), Positives = 100/231 (43%), Gaps = 21/231 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+ GR PH+ P+ +L CG L+ +V++AAHC + V LG H+L Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLGDHSL 56 Query: 90 SRREPTRQVFAV-QRIFENGYD---PVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 R+ Q V Q I Y+ P + +DI++++L SA + V+ QL Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQL--ANLCP 114 Query: 146 GNGVQCLAMGWGL-LGRNRGIASVLQELNVTVVT-SLCRRS--------NVCTLVRGRQA 195 G +C+ GWG + L V + + + C R+ VC A Sbjct: 115 KVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNG-A 173 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG PLVC+G++ GI S+ C P + + ++ WI + Sbjct: 174 DTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >3QUM-P nrPDB Length = 237 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 73/242 (30%), Positives = 111/242 (45%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG H+ P+ V + RG CG L+ P +V++AAHC+ N +V ++LG H+L Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV----ILLGRHSL 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNL------------LNDIVILQLNGSATINANVQVAQ 137 E T QVF V F + ++L +D+++L+L+ A + V+V Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNRGI-ASVLQELNVTVVTSLCRRS---------NVC 187 LP Q L G C A GWG + + LQ +++ V+++ +C Sbjct: 117 LPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 174 Query: 188 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 175 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 234 Query: 248 RS 249 + Sbjct: 235 AN 236 >3BSQ-A nrPDB Length = 227 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 58/228 (25%), Positives = 102/228 (44%), Gaps = 17/228 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+ G + P+ V+L CG L+ +V++AAHC + V LG+ L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 R +++ A + GY +ND+++++LN A +++ V+ +LP++ G Sbjct: 57 GDRR-AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 113 Query: 150 QCLAMGWGLL-GRNRGIASVLQELNVTVVT---------SLCRRSNVCTLVRGRQAGVCF 199 C GWG + S L ++V +++ L S +C + + C Sbjct: 114 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACN 173 Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GDSG PLVC G + G+ S+ C P + V +F WI+ ++ Sbjct: 174 GDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >2AIQ-A nrPDB Length = 231 Score = 257 bits (656), Expect = 5e-69, Method: Composition-based stats. Identities = 65/237 (27%), Positives = 104/237 (43%), Gaps = 18/237 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG + F+ L G CG TLI +V++A HC + +R+ LG HNL Sbjct: 1 VIGGDECNINEHRFLA-LVYANGSLCGGTLINQEWVLTARHC----DRGNMRIYLGMHNL 55 Query: 90 S--RREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 ++ R+ + N + DI++++LN +A++ LP+ + Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSV-- 113 Query: 148 GVQCLAMGWGL-LGRNRGIASVLQELNVTVVT-SLCRRSN-------VCTLVRGRQAGVC 198 G C MGWG N + V N+ ++ ++C+ + +C + C Sbjct: 114 GSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEGGKDTC 173 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 GDSG PL+CNG GI S CA P + V + +WI SII + D CP Sbjct: 174 KGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGNTDATCP 230 >1FDP-A nrPDB Length = 235 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 74/233 (31%), Positives = 119/233 (51%), Gaps = 14/233 (6%) Query: 27 ASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GGR A HA P+M S+QL G H CG L+A +V+SAAHC+ + V+V+LGA Sbjct: 5 RGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGA 64 Query: 87 HNLSRREPTRQVFAV-QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 H+LS+ EP+++++ V + + P + +D+++LQL+ AT+ V+ R + Sbjct: 65 HSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDV 124 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN----------VCTLVRGRQ 194 G C GWG++ LQ + + V+ + C R +C + Sbjct: 125 APGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--ESNR 182 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PLVC G++ G+ + C + P + VA + WIDS++ Sbjct: 183 RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 235 >1BRU-P nrPDB Length = 241 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 81/244 (33%), Positives = 121/244 (49%), Gaps = 27/244 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGG ARP++WP+ VSLQ H CG TL+ ++V++AAHC+++ R RVVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS--RTYRVVLG 58 Query: 86 AHNLSRREPTRQVFAVQRIFEN---GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 H+LS EP V ++ + + ++ NDI +L+L ++ +Q+ LPA G Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-----------SLCRRSNVCTLVR 191 L N C GWG L N +LQ+ + VV S + + +C Sbjct: 119 TILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGD 178 Query: 192 GRQAGVCFGDSGSPLVC-----NGLIHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDSI 245 G + C GDSG PL C +HGI SF GC P F V+ +++WI+S+ Sbjct: 179 GIIS-SCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSV 237 Query: 246 IQRS 249 I + Sbjct: 238 IANN 241 >1EKB-B nrPDB Length = 235 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 71/236 (30%), Positives = 104/236 (44%), Gaps = 19/236 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVN--VRAVRVVLGAH 87 IVGG +R AWP++V+L CGA+L++ ++++SAAHCV N + VLG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 88 NLSRREPT--RQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 S Q + Y+ NDI ++ L +Q LP + + Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL-CRR---------SNVCTLVRGRQA 195 G C GWG L A VLQE +V ++++ C++ + VC Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEAGGV 180 Query: 196 GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PL+C L+ G+ SF CA P +A V +F WI S + Sbjct: 181 DSCQGDSGGPLMCQENNRWLLAGVTSFGYQ-CALPNRPGVYARVPRFTEWIQSFLH 235 >1NN6-A nrPDB Length = 228 Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats. Identities = 70/235 (29%), Positives = 109/235 (46%), Gaps = 20/235 (8%) Query: 28 SEIVGGRRARPHAWPFMVSLQ----LRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVV 83 EI+GG +PH+ P+M L+ FCG LI NFV++AAHC R++ V Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVT 56 Query: 84 LGAHNLSRREPTRQVFAV-QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 LGAHN++ E T Q V ++ Y+ L +DI++L+L A++ V P+Q Sbjct: 57 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 116 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRS--------NVCTLVRGRQ 194 + G C GWG G + + LQE+ + ++ +C + Sbjct: 117 NFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKT 176 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GDSG PL+C G+ GI S+ R P F ++ + WI+ I+Q + Sbjct: 177 KSAFKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQAN 228 >1AO5-A nrPDB Length = 237 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 63/242 (26%), Positives = 110/242 (45%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 +VGG ++ P+ V++ + H CG L+ N+V++AAHC V V LG + L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY----VDQYEVWLGKNKL 56 Query: 90 SRREPTRQVFAVQRIF-ENGYDP-----------VNLLNDIVILQLNGSATINANVQVAQ 137 + EP+ Q V + F G++ + +D+++L+L+ A I V+ Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNRGI-ASVLQELNVTVVTSL-CRRS--------NVC 187 LP + G +CLA GWG + R LQ + +T++ + C + +C Sbjct: 117 LPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 174 Query: 188 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G C DSG PL+C+G++ G S+ C P + + +F +WI + Sbjct: 175 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 234 Query: 248 RS 249 ++ Sbjct: 235 KN 236 >4KKD-A nrPDB Length = 433 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 63/303 (20%), Positives = 111/303 (36%), Gaps = 51/303 (16%) Query: 3 LGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRG-------GHFC 55 LGR L C P+ L +L I+GGR A P +P+ + + F Sbjct: 130 LGRSLPTCLPECGQPSRSL--PSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFG 187 Query: 56 GATLIAPNFVMSAAH---------CVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFE 106 L++ +++++AAH V V+ V V LG H++ + A + + Sbjct: 188 SGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLH 247 Query: 107 NGYDPVNLLNDIVILQLNGSATINANVQVAQLPA-QGRRLGNGVQCLAMGWGLLGRN--- 162 ++ N +DI ++QL + +V LP + + L GWG+ N Sbjct: 248 PDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTV 307 Query: 163 --------RGIASVLQELNVTVV-TSLCR-------------RSNVCTLVRGRQAGVCFG 200 R ++ VLQ + + VV + C+ + C C G Sbjct: 308 DEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLG 367 Query: 201 DSGSPLV------CNGLIHGIASFVR-GGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNP 253 DSG V ++ G+ S+ C S + V+ +V+W+ + + Sbjct: 368 DSGEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVV 427 Query: 254 CPH 256 P Sbjct: 428 EPQ 430 >3DFJ-A nrPDB Length = 263 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 68/249 (27%), Positives = 104/249 (41%), Gaps = 26/249 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVR-AVRVVLGAHN 88 I GG A WP+ VS+ G H CG +L++ +V+SAAHC + + + A V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 89 LSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 L +V ++ I Y DI +LQL+ T + ++ LPA N Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 148 GVQCLAMGWGLLGRNRGI--ASVLQELNVTVVT-SLC----------------RRSNVCT 188 G+ C GWG + + + LQ+L V +++ C + VC Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCA 180 Query: 189 LVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG PL C + GI S+ C + P + + + +WI S Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYTLASSYASWIQS 239 Query: 245 IIQRSEDNP 253 + + P Sbjct: 240 KVTELQLVP 248 >4Z6A-H nrPDB Length = 249 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 77/251 (30%), Positives = 108/251 (43%), Gaps = 20/251 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNV-RAVRVVLGAHN 88 IVGG+ P+ V L + G CG TLI +V+SAAHC + R + VLG H+ Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 89 LSRREPTRQVFAV-QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA---QGRR 144 LS + Q V Q I + Y P +DI +L+L+ + +V LP R Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVT-VVTSLCRRS--------NVCTLVRGRQA 195 L L GWG L A L LNV ++T C S C Sbjct: 121 LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGSK 180 Query: 196 GVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSED 251 C GDSG P + + GI S+ + GCA+ + + V+Q++ W+ ++ RSE Sbjct: 181 DSCKGDSGGPHATHYRGTWYLTGIVSWGQ-GCATVGHFGVYTRVSQYIEWLQKLM-RSEP 238 Query: 252 NPCPHPRDPDP 262 P R P P Sbjct: 239 RPGVLLRAPFP 249 >5MS3-A nrPDB Length = 228 Score = 254 bits (649), Expect = 4e-68, Method: Composition-based stats. Identities = 62/234 (26%), Positives = 100/234 (42%), Gaps = 21/234 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG +PH+ P+ +L CG L+ N+V++AAHC V LG H+L Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC----KKPKYTVRLGDHSL 56 Query: 90 SRREPTRQ-VFAVQRIFENGYDP---VNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 ++ Q + VQ I Y+ + +D+++LQL A++ + V+ L + Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQ- 115 Query: 146 GNGVQCLAMGWGL-LGRNRGIASVLQELNVTVV-TSLCRRS--------NVCTLVRGRQA 195 G +C GWG L V + C + VC + A Sbjct: 116 -PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG-SSKGA 173 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 C GDSG PLVC+G + GI S+ C P + + ++++WI II Sbjct: 174 DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 227 >1OP0-A nrPDB Length = 234 Score = 253 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 59/239 (24%), Positives = 96/239 (40%), Gaps = 19/239 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG + F+V+ G FCG TLI P +V++AAHC + ++ LG H+ Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHC----DSTDFQMQLGVHSK 56 Query: 90 SRREPTRQVF--AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 Q + I N + L DI++++L+ + + ++ Sbjct: 57 KVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS--LPSSPPSV 114 Query: 148 GVQCLAMGWGLLGR-NRGIASVLQELNVTVVTSLCRRS----------NVCTLVRGRQAG 196 G C MGWG + V N+ ++ ++ +C + Sbjct: 115 GSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKD 174 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 C GDSG PL+CNG GI S+ C G P + V + +WI I + D CP Sbjct: 175 TCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGNTDATCP 233 >5FCR-A nrPDB Length = 234 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 71/233 (30%), Positives = 124/233 (53%), Gaps = 15/233 (6%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 I+GG+ A HA P+M S+Q+ G H CG TL+ +V+SAAHC+ V + +V+V+LGAH+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 89 LSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 LS EP ++ + VQ + G P +L +D+++ +L+ +A++ +V+ L + + + Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP 120 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRR-----------SNVCTLVRGRQAG 196 G C GWG++ VL +L V+++ + +C + Sbjct: 121 GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESNRRD 178 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 C GDSGSPLVC + G+ ++ C +G P + V+ + WI++I + Sbjct: 179 TCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >5ZFH-A nrPDB Length = 224 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 54/231 (23%), Positives = 103/231 (44%), Gaps = 17/231 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+ G + + + P+ V+L CG L+ +V++AAHC + +V LG+ + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHC----KMGQYQVQLGSDKI 56 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 + +++ A + GY +NDI++++L+ +++ V+ QLP G Sbjct: 57 GDQS-AQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE--PPGT 113 Query: 150 QCLAMGWGLL-GRNRGIASVLQELNVTVVTS-LCRR--------SNVCTLVRGRQAGVCF 199 C GWG + S L +V +++S C++ + +C + + C Sbjct: 114 SCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTCN 173 Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 GDSG PLVCN + G+ S+ C P + V ++ W+ ++ Sbjct: 174 GDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTHR 224 >1X7A-C nrPDB Length = 235 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 68/237 (28%), Positives = 103/237 (43%), Gaps = 23/237 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG A+P +P+ V L + FCG ++I +V++AAHC+ + VV G +N Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCI--EPGVKITVVAGEYNT 58 Query: 90 SRREPTRQVFAV-QRIFENGYDPVN--LLNDIVILQLNGSATINANVQVAQLPAQGRR-- 144 EPT Q V + I + Y+ +DI +L+L+ T+N+ V + + Sbjct: 59 EETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNI 118 Query: 145 -LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRS--------NVCTLVRGRQ 194 L G GWG + A++LQ L V +V + C RS C Sbjct: 119 FLKFGS-GYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGG 177 Query: 195 AGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG P V + GI S+ CA + V+++VNWI + Sbjct: 178 KDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWIKEKTK 233 >1TON-A nrPDB Length = 235 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 69/242 (28%), Positives = 119/242 (49%), Gaps = 30/242 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG + ++ P+ V++ + CG LI P++V++AAHC +N +V+LG +NL Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSN----NYQVLLGRNNL 54 Query: 90 SRREPTRQVFAVQRIF-ENGYDPV-----------NLLNDIVILQLNGSATINANVQVAQ 137 + EP Q V++ F Y P+ + ND+++L L+ A I V+V Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 138 LPAQGRRLGNGVQCLAMGWGLLGRNRGI-ASVLQELNVTVVTSL---------CRRSNVC 187 LP + ++ G CLA GWG + + + LQ +N+ ++++ +C Sbjct: 115 LPTKEPKV--GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLC 172 Query: 188 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PL+C+G++ GI S CA P +A + +F +WI +++ Sbjct: 173 AGEMEGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMK 232 Query: 248 RS 249 + Sbjct: 233 EN 234 >2CGA-A nrPDB Length = 245 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 77/252 (30%), Positives = 123/252 (48%), Gaps = 23/252 (9%) Query: 14 CVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGG-HFCGATLIAPNFVMSAAHCV 72 C +PA+ + L+ IV G A P +WP+ VSLQ + G HFCG +LI N+V++AAHC Sbjct: 1 CGVPAIQPVLSGLS-RIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC- 58 Query: 73 ANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINA 131 V V VV G + Q + ++F+N Y+ + + NDI +L+L+ +A+ + Sbjct: 59 -GVTTSDV-VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQ 116 Query: 132 NVQVAQLPAQGRRLGNGVQCLAMGWGLLG-RNRGIASVLQELNVTVVTSL-CRR------ 183 V LP+ G C+ GWGL N LQ+ ++ ++++ C++ Sbjct: 117 TVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKI 176 Query: 184 --SNVCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQ 237 + +C G C GDSG PLVC + GI S+ C++ P +A V Sbjct: 177 KDAMICAGASG--VSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCST-STPGVYARVTA 233 Query: 238 FVNWIDSIIQRS 249 VNW+ + + Sbjct: 234 LVNWVQQTLAAN 245 >3LC3-A nrPDB Length = 235 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 67/237 (28%), Positives = 101/237 (42%), Gaps = 23/237 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 +VGG A+P +P+ V L + FCG +++ ++++AAHCV + VV G HN+ Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCV--ETGVKITVVAGEHNI 58 Query: 90 SRREPTRQVFAVQRIF-ENGYDPV--NLLNDIVILQLNGSATINANVQVAQLPAQGRR-- 144 E T Q V RI + Y+ +DI +L+L+ +N+ V + + Sbjct: 59 EETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNI 118 Query: 145 -LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRS--------NVCTLVRGRQ 194 L G GWG + A VLQ L V +V + C RS C Sbjct: 119 FLKFGS-GYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGG 177 Query: 195 AGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG P V + GI S+ CA + V+++VNWI + Sbjct: 178 RDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAMKGKYGIYTKVSRYVNWIKEKTK 233 >3S69-A nrPDB Length = 234 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 59/240 (24%), Positives = 95/240 (39%), Gaps = 19/240 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 ++GG + +V+ G FC TLI +V++AAHC + ++ LG H+ Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHC----DNTNFQMKLGVHSK 56 Query: 90 SRREPTRQVF--AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 Q + I N + L DI++++L+ + + ++ L Sbjct: 57 KVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI--VPLSLPSSPPSV 114 Query: 148 GVQCLAMGWGLLGR-NRGIASVLQELNVTVVTSLCRRS----------NVCTLVRGRQAG 196 G C MGWG + V + ++ ++ +C + Sbjct: 115 GSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKD 174 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPH 256 C GDSG PL+CNG GI SF C GL P + V + +WI SII + CP Sbjct: 175 TCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGNTTVTCPQ 234 >2F91-A nrPDB Length = 237 Score = 250 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 75/236 (31%), Positives = 107/236 (45%), Gaps = 25/236 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLR----GGHFCGATLIAPNFVMSAAHCVAN---VNVRAVRV 82 IVGG A +P+ +S Q HFCGA++ N+ ++A HCV N +++ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 83 VLGAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQ 141 V G ++S E + Q+ V +I +D L NDI +L+L+GS T N NV LP Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 142 GRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL-CR---------RSNVCTLVR 191 G + GWG VLQ++ V +V+ CR S +C V Sbjct: 121 GHTATGD--VIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVP 178 Query: 192 GRQAGVCFGDSGSPLVCNGL----IHGIASFVRGGCASGLYPDAFAPVAQFVNWID 243 C GDSG PL + + GI S+ GCA YP + V+ V+WI Sbjct: 179 EGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGY-GCARPGYPGVYTEVSYHVDWIK 233 >4E7N-A nrPDB Length = 238 Score = 250 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 62/243 (25%), Positives = 100/243 (41%), Gaps = 23/243 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 I+GG + F+V+L FCG TLI +V++AAHC + + R+ LG H Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHC----DRKNFRIKLGMH 56 Query: 88 NLSRREPTRQVF--AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 + Q + + + DI++++L+ + ++ Sbjct: 57 SKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFS--LPSSPP 114 Query: 146 GNGVQCLAMGWGLLGRN-RGIASVLQELNVTVVT-SLCRRSN-----------VCTLVRG 192 G C MGWG + V +N+ ++ +CR +C + Sbjct: 115 SVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILE 174 Query: 193 RQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDN 252 C GDSG PL+CNG GIAS+ CA P A+ V ++WI++II + D Sbjct: 175 GGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGNTDA 234 Query: 253 PCP 255 CP Sbjct: 235 SCP 237 >1GVZ-A nrPDB Length = 237 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 68/245 (27%), Positives = 112/245 (45%), Gaps = 32/245 (13%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG H+ P+ V++ +G CG L+ P +V++AAHC++ ++ LG HNL Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMS----DDYQIWLGRHNL 56 Query: 90 SRREPTRQVFAV--------------QRIFENGYDPVNLLNDIVILQLNGSATINANVQV 135 S+ E T Q V ++ + YD + +D+++L+L A I V++ Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDD--ISHDLMLLRLAQPARITDAVKI 114 Query: 136 AQLPAQGRRLGNGVQCLAMGWGLLGR-NRGIASVLQELNVTVVTSL-CRRSN-------- 185 LP Q +L G C GWGL+ + LQ + + + ++ C R+ Sbjct: 115 LDLPTQEPKL--GSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFV 172 Query: 186 VCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSI 245 +C R +C GDSG L+C+G+ GI S+ CA F V WI Sbjct: 173 LCATHRDDSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKET 232 Query: 246 IQRSE 250 I+++ Sbjct: 233 IEKNS 237 >1KIG-H nrPDB Length = 241 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 60/243 (24%), Positives = 91/243 (37%), Gaps = 21/243 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLR-GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IVGGR P+ L FCG T++ +V++AAHC+ V +G N Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKR--FTVRVGDRN 58 Query: 89 LSRREPTRQVFAVQ-RIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG---RR 144 + E V+ + + + DI +L+L NV A LP + Sbjct: 59 TEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEAT 118 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR--------RSNVCTLVRGRQA 195 L + G+G ++S L+ L V V S C+ + C + Sbjct: 119 LMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPE 178 Query: 196 GVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSED 251 C GDSG P V + GI S+ GCA + V+ F+ WID I++ Sbjct: 179 DACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKFGVYTKVSNFLKWIDKIMKARAG 237 Query: 252 NPC 254 Sbjct: 238 AAG 240 >1ORF-A nrPDB Length = 234 Score = 248 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 78/235 (33%), Positives = 119/235 (50%), Gaps = 19/235 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG PH+ P+MV L L C LIA ++V++AAHC N+N R+ +V+LGAH++ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC--NLNKRS-QVILGAHSI 57 Query: 90 SRREPTRQVFAVQRIFE-NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 +R EPT+Q+ V++ F YDP D+ +LQL A IN V + LP +G + G Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPG 117 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR------------SNVCTLVRGRQA 195 C GWG + + L+E+ +T++ +C + VC Sbjct: 118 TMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGR 177 Query: 196 GVCFGDSGSPLVCNGLIHGIASFV-RGGCASGLYPDAFAPVA-QFVNWIDSIIQR 248 C GDSGSPL+C G+ G+ SF C P + ++ + +NWI I+ Sbjct: 178 DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 232 >3G01-A nrPDB Length = 227 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 108/233 (46%), Gaps = 22/233 (9%) Query: 30 IVGGRRARPHAWPFMVS---LQLRGGH-FCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG PH+ P+M L++ G FCG L+ FV++AAHC R++ V LG Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC----KGRSMTVTLG 56 Query: 86 AHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AHN+ +E T+Q+ V + I Y+P + NDI++L+L +A V+ LP + Sbjct: 57 AHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAH 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSN----------VCTLVRGRQ 194 + G +C GWG + + L E+ +TV S +C + Sbjct: 117 VKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIK 176 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GDSG PLVC GI S+ + G P F V FV+WI ++ Sbjct: 177 GASFRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTMK 226 >1BQY-A nrPDB Length = 234 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 56/239 (23%), Positives = 95/239 (39%), Gaps = 19/239 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 + GG + +V L G CG TLI ++V++AAHC + +++ G H+ Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHC----DSNNFQLLFGVHSK 56 Query: 90 SRREPTRQVF--AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 Q + N + DI++++L+ S + + ++ Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS--LPSSPPSV 114 Query: 148 GVQCLAMGWGLLGRNRG-IASVLQELNVTVVTSLCRRS----------NVCTLVRGRQAG 196 G C MGWG + V N+ ++ R+ +C + Sbjct: 115 GSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRD 174 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 C DSG PL+CNG+ GI S+ C P + V +++WI SII ++D CP Sbjct: 175 TCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGNKDATCP 233 >4H4F-A nrPDB Length = 249 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 82/241 (34%), Positives = 117/241 (48%), Gaps = 26/241 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRG----GHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGG ARPH+WP+ +SLQ H CG TLIA NFV++AAHC++N R RV +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT--RTYRVAVG 58 Query: 86 AHNLS-RREPTRQVFAVQRI-FENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 143 +NL E V I ++ + L NDI +++L ++ +QVA LP + Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 144 RLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLC----------RRSNVCTLVRG 192 L C GWG L N IA LQ+ VV + C +++ VC G Sbjct: 119 LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDG 178 Query: 193 RQAGVCFGDSGSPLVCN-----GLIHGIASFVR-GGCASGLYPDAFAPVAQFVNWIDSII 246 + C GDSG PL C + GI SF GC + P + V+ +++WI+ + Sbjct: 179 VIS-ACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 237 Query: 247 Q 247 Q Sbjct: 238 Q 238 >4MPW-A nrPDB Length = 245 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 36/250 (14%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVAN--VNVRAVRVVL 84 IVGG+ A WP+ VSL++ G HFCG +LI P +V++AAHCV ++ A+RV L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 85 GAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 143 +L ++ Q+ V RI + + DI +L+L ++++V LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 144 RLGNGVQCLAMGWGLLGRNRGIAS--VLQELNVTVVTS------------------LCRR 183 G+ C GWG + + + L+++ V ++ + + R Sbjct: 118 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 177 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFV 239 +C + C GDSG PLVC L G+ S+ GCA P + V ++ Sbjct: 178 DMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYL 234 Query: 240 NWIDSIIQRS 249 +WI + + Sbjct: 235 DWIHHYVPKK 244 >3P8G-A nrPDB Length = 241 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 68/238 (28%), Positives = 100/238 (42%), Gaps = 24/238 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRG-GHFCGATLIAPNFVMSAAHCVAN------VNVRAVRV 82 +VGG A WP+ VSL G GH CGA+LI+PN+++SAAHC + + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 83 VLGAHNLSRRE-PTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA 140 LG H+ S+R P Q ++RI ++ DI +L+L A ++ V+ LP Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 141 QGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRS---------NVCTLVR 191 G GWG A +LQ+ + V+ + +C Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVGFL 180 Query: 192 GRQAGVCFGDSGSPLV---CNGLI--HGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG PL +G I G+ S+ GCA P + + F +WI Sbjct: 181 SGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG-DGCAQRNKPGVYTRLPLFRDWIKE 237 >1C5M-D nrPDB Length = 255 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 59/236 (25%), Positives = 95/236 (40%), Gaps = 21/236 (8%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IVGG+ + P+ L FCG T+++ ++++AAHC+ +V +G N Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKR--FKVRVGDRN 58 Query: 89 LSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG---RR 144 + E V V+ + N + DI +L+L T NV A LP + Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 118 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR--------RSNVCTLVRGRQA 195 L + G+G ++ L+ L V V + C+ ++ C +Q Sbjct: 119 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQE 178 Query: 196 GVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG P V + GI S+ GCA + V F+ WID ++ Sbjct: 179 DACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKYGIYTKVTAFLKWIDRSMK 233 >6AOD-C nrPDB Length = 245 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 63/232 (27%), Positives = 100/232 (43%), Gaps = 20/232 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRG---GHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLG 85 IVGG + WP+ V+L H CG ++I ++++AAHC V + + +RV G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 86 AHNLSRREPTRQVFAV-QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 S + F V + I + Y DI +L+L + + + LP++G R Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRS---------NVCTLVRGRQ 194 C GWG I + LQ+ + +VT+ C++ +C R Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG 180 Query: 195 AGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 242 C GD+G PL C + GI S+ GCA P + V ++V+WI Sbjct: 181 KDACKGDAGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 231 >2V35-A nrPDB Length = 240 Score = 247 bits (630), Expect = 4e-66, Method: Composition-based stats. Identities = 91/243 (37%), Positives = 125/243 (51%), Gaps = 26/243 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGG A+ ++WP +SLQ R G H CG TLI N+VM+AAHCV RVV+G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRE--LTFRVVVG 58 Query: 86 AHNLSRREPTRQVFAVQRIFENGY---DPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 HNL++ + T Q VQ+I + Y D V DI +L+L S T+N+ VQ+ LP G Sbjct: 59 EHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAG 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-----------SLCRRSNVCTLVR 191 L N C GWGL N +A LQ+ + V S + S VC Sbjct: 119 TILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGD 178 Query: 192 GRQAGVCFGDSGSPLVC----NGLIHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDSII 246 G ++G C GDSG PL C +HG+ SFV GC P F V+ +++WI+++I Sbjct: 179 GVRSG-CQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVI 237 Query: 247 QRS 249 + Sbjct: 238 ASN 240 >2PSX-A nrPDB Length = 227 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 65/234 (27%), Positives = 101/234 (43%), Gaps = 20/234 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHF-CGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 I+ G H P+ +L LR CGA L+ P ++++AAHC + RV LG ++ Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYS 56 Query: 89 LS--RREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 LS + V+ I GY ND+++++LN +V+ + + Sbjct: 57 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC--PS 114 Query: 147 NGVQCLAMGWGLLG-RNRGIASVLQELNVTVVTSL-CRR--------SNVCTLVRGRQAG 196 G +CL GWG VLQ LN++V++ C + C Sbjct: 115 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRD 173 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 C GDSG P+VCNG + G+ S+ CA P + + +F WI IQ + Sbjct: 174 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 227 >1SGF-A nrPDB Length = 240 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 57/237 (24%), Positives = 101/237 (42%), Gaps = 29/237 (12%) Query: 35 RARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREP 94 ++ P+ V++ + CG L+ N+V++AAHC +V LG +N EP Sbjct: 10 DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCY----NDKYQVWLGKNNFLEDEP 64 Query: 95 TRQVFAVQR-IFENGYDP-----------VNLLNDIVILQLNGSATINANVQVAQLPAQG 142 + Q V + I ++ + ND+++L+L+ A I V+ LP + Sbjct: 65 SDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEE 124 Query: 143 RRLGNGVQCLAMGWGLLGR-NRGIASVLQELNVTVVTSL---------CRRSNVCTLVRG 192 +L G CLA GWG LQ +N+ ++ + + +C Sbjct: 125 PKL--GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMD 182 Query: 193 RQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + C DSG PL+C+G++ GI S+ C P + + +F +WI + + Sbjct: 183 GGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANN 239 >3TK9-A nrPDB Length = 226 Score = 246 bits (628), Expect = 9e-66, Method: Composition-based stats. Identities = 74/233 (31%), Positives = 116/233 (49%), Gaps = 22/233 (9%) Query: 30 IVGGRRARPHAWPFMVS---LQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GG A+PH+ P+M LQ + CG L+ +FV++AAHC + ++ V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGS----SINVTLGA 56 Query: 87 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 HN+ +E T+Q V+R I Y+P N N+I++LQL A V+ +LP+ ++ Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQV 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT----------SLCRRSNVCTLVRGRQA 195 G C GWG + + +A+ LQE+ +TV + R + +C + Sbjct: 117 KPGQLCSVAGWGYVSMS-TLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQ 175 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GDSG PLVC + GI S+ G P + V+ F+ WI ++R Sbjct: 176 TGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFLPWIKRTMKR 225 >3S9B-A nrPDB Length = 234 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 67/240 (27%), Positives = 103/240 (42%), Gaps = 21/240 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 +VGG + PF+V+L C LI +V++AAHC + R +R+ LG H Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHC----DRRNIRIKLGMH 56 Query: 88 NLSRREPTRQVFAV--QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 + + R Q+ + N P L DI++++L T + ++ LP++ R + Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRS----------NVCTLVRGRQA 195 G +C MGWG + V N+ +V +C + Sbjct: 117 --GSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGR 173 Query: 196 GVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 C GDSG PL+CNG +HGI + C L P + V + NWI SII + CP Sbjct: 174 DTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGNRTVTCP 233 >3K65-B nrPDB Length = 308 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 65/269 (24%), Positives = 106/269 (39%), Gaps = 39/269 (14%) Query: 18 ALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV--- 72 L + + IV G A P+ V L + CGA+LI+ +V++AAHC+ Sbjct: 38 ERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYP 97 Query: 73 ---ANVNVRAVRVVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGS 126 N + V +G H+ +R E ++ +++I Y+ NL DI +++L Sbjct: 98 PWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKP 157 Query: 127 ATINANVQVAQLPAQGRR---LGNGVQCLAMGWGLLGR------NRGIASVLQELNVTVV 177 + + LP + L G + GWG L +G SVLQ +N+ +V Sbjct: 158 VAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIV 217 Query: 178 TS-LCRRS--------NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIASFV 219 +C+ S C G++ C GD+G P V GI S+ Sbjct: 218 ERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWG 277 Query: 220 RGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GC + V + WI +I + Sbjct: 278 E-GCDRDGKYGFYTHVFRLKKWIQKVIDQ 305 >1MKW-K nrPDB Length = 308 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 67/271 (24%), Positives = 105/271 (38%), Gaps = 39/271 (14%) Query: 16 LPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV- 72 L + + IV G+ A P+ V L + CGA+LI+ +V++AAHC+ Sbjct: 36 QTEKELFESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLL 95 Query: 73 -----ANVNVRAVRVVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLN 124 N V + V +G H+ +R E ++ + +I Y+ NL DI +L+L Sbjct: 96 YPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLK 155 Query: 125 GSATINANVQVAQLPAQGRR---LGNGVQCLAMGWG------LLGRNRGIASVLQELNVT 175 ++ + LP + L G + GWG SVLQ +N+ Sbjct: 156 RPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLP 215 Query: 176 VVTS-LCRRS--------NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIAS 217 +V +C+ S C G++ C GDSG P V GI S Sbjct: 216 LVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVS 275 Query: 218 FVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 + GC + V + WI +I R Sbjct: 276 WGE-GCDRDGKYGFYTHVFRLKKWIQKVIDR 305 >2BDH-A nrPDB Length = 223 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 68/229 (29%), Positives = 108/229 (47%), Gaps = 18/229 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+ G PH+ P+ +L + FC L+ P +V+SAAHC N + + LG H+L Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLHSL 56 Query: 90 S-RREPTRQVFAVQ-RIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 +EP Q+ + Y+ L ND+++++L+ S + + ++ + +Q Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC--PTA 114 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNV---------TVVTSLCRRSNVCTLVRGRQAGVC 198 G CL GWGLL N + +VLQ +NV + L S C Q C Sbjct: 115 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSC 173 Query: 199 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 GDSG PL+CNG + G+ SF + C P + + +F WI+ +Q Sbjct: 174 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >1PYT-D nrPDB Length = 251 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 84/256 (32%), Positives = 124/256 (48%), Gaps = 28/256 (10%) Query: 14 CVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRG----GHFCGATLIAPNFVMSAA 69 C P + L++ +VGG A PH+WP+ +SLQ H CG TLI PN V++AA Sbjct: 1 CGAP---IFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAA 57 Query: 70 HCVANVNVRAVRVVLGAHNLSRREPTRQVF-AVQRIF-ENGYDPVNLLNDIVILQLNGSA 127 HC++N RV LG +NL + ++ V IF ++ + NDI +++L + Sbjct: 58 HCISNT--LTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETV 115 Query: 128 TINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLC----- 181 + +QVA LP++G L C GWG L N IA+ LQ+ VV + C Sbjct: 116 ELGDTIQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDW 175 Query: 182 -----RRSNVCTLVRGRQAGVCFGDSGSPLVC----NGLIHGIASFVRG-GCASGLYPDA 231 + + VC G + C GDSG PL C + GI SF G C + P Sbjct: 176 WGTTVKETMVCAGGDGVIS-ACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTV 234 Query: 232 FAPVAQFVNWIDSIIQ 247 F V+ +++WI+ +Q Sbjct: 235 FTRVSAYIDWINQKLQ 250 >6QHB-A nrPDB Length = 223 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 61/229 (26%), Positives = 95/229 (41%), Gaps = 17/229 (7%) Query: 31 VGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL- 89 V G + P+ +L G CG LI P +V++AAHC ++V LG HNL Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHNLG 57 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 + Q V+ + YD + DI++L+L A ++ +Q LP + Sbjct: 58 QQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSAQTT 115 Query: 150 QCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR--------RSNVCTLVRGRQAGVCFG 200 C +GWG + +Q + +V+ C ++ +C C G Sbjct: 116 SCHILGWGKTA-DGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQG 174 Query: 201 DSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 DSG PLVC + G+ S+ C S P + V ++ NWI IQ Sbjct: 175 DSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >4IGD-A nrPDB Length = 406 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 66/277 (23%), Positives = 107/277 (38%), Gaps = 41/277 (14%) Query: 3 LGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSL-QLRGGHFCGATLIA 61 LGR L C LP L ++I GR A+ P++ L L G FCG +L+ Sbjct: 132 LGRSLPTCLPVCGLPKFS---RKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLG 188 Query: 62 PNFVMSAAHCVANV--------------NVRAVRVVLGAHNLSRREPTRQVFAVQRI-FE 106 +++++AAHC+ + +++LG H R + Q V+ Sbjct: 189 SSWIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLH 248 Query: 107 NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIA 166 YDP ND+ +++L S +NA V LP ++ G + GWG R Sbjct: 249 PQYDPNTFENDVALVELLESPVLNAFVMPICLPEGPQQ--EGAMVIVSGWGKQFLQR-FP 305 Query: 167 SVLQELNVTVVT-SLCR-----------RSNVCTLVRGRQAGVCFGDSGSPLVC------ 208 L E+ + +V S C+ R +C + C GDSG P+V Sbjct: 306 ETLMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERG 365 Query: 209 NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSI 245 + G S+ C ++ + +WI + Sbjct: 366 QWYLVGTVSWGDD-CGKKDRYGVYSYIHHNKDWIQRV 401 >2OQ5-A nrPDB Length = 232 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 60/233 (25%), Positives = 88/233 (37%), Gaps = 21/233 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG WP+ SLQ G H CGATLI +++SAAHC A + Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 90 SRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 P++ ++RI Y + DI + +L+ V LP G Sbjct: 61 K---PSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPG 117 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRS----------NVCTLVRGRQAGV 197 G+G L + + L++ VT++ + C +C + Sbjct: 118 DVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDA 177 Query: 198 CFGDSGSPLVCN-----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSI 245 C GDSG PLV + + GI S+ CA P + V +WI S Sbjct: 178 CQGDSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTALRDWITSK 229 >3NXP-A nrPDB Length = 424 Score = 243 bits (621), Expect = 6e-65, Method: Composition-based stats. Identities = 66/269 (24%), Positives = 106/269 (39%), Gaps = 39/269 (14%) Query: 18 ALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV--- 72 L + + IV G A P+ V L + CGA+LI+ +V++AAHC+ Sbjct: 154 ERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYP 213 Query: 73 ---ANVNVRAVRVVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGS 126 N + V +G H+ +R E ++ +++I Y+ NL DI +++L Sbjct: 214 PWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKP 273 Query: 127 ATINANVQVAQLPAQGRR---LGNGVQCLAMGWGLLGR------NRGIASVLQELNVTVV 177 + + LP + L G + GWG L +G SVLQ +N+ +V Sbjct: 274 VAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIV 333 Query: 178 TS-LCRRS--------NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIASFV 219 +C+ S C G++ C GDSG P V GI S+ Sbjct: 334 ERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 393 Query: 220 RGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GC + V + WI +I + Sbjct: 394 E-GCDRDGKYGFYTHVFRLKKWIQKVIDQ 421 >1LTO-A nrPDB Length = 245 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 110/250 (44%), Gaps = 36/250 (14%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVAN--VNVRAVRVVL 84 IVGG+ A WP+ VSL++R HFCG +LI P +V++AAHC+ ++ +RV L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 85 GAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGR 143 +L ++ Q+ V RI + + DI +L+L I++ V LP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 144 RLGNGVQCLAMGWGLLGRNRGIAS--VLQELNVTVVTS------------------LCRR 183 G+ C GWG + + + L+++ V ++ + + R Sbjct: 118 TFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRD 177 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFV 239 +C Q C GDSG PLVC L G+ S+ GCA P + V ++ Sbjct: 178 DMLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNRPGIYTRVTYYL 234 Query: 240 NWIDSIIQRS 249 +WI + + Sbjct: 235 DWIHHYVPKK 244 >1Q3X-A nrPDB Length = 328 Score = 243 bits (620), Expect = 8e-65, Method: Composition-based stats. Identities = 65/267 (24%), Positives = 102/267 (38%), Gaps = 33/267 (12%) Query: 5 RRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNF 64 + L C L A GG I GG++A+P +P+ V + GG L+ N+ Sbjct: 67 KSLPVCEPVCGLSARTTGG-----RIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNW 119 Query: 65 VMSAAHCVANVNVRAVRVVLGAHNLSRREPT-RQVFAVQRIFENGY-DPVNLLNDIVILQ 122 V++AAH V A + + L R P Q ++ GY NDI +++ Sbjct: 120 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIK 179 Query: 123 LNGSATINANVQVAQLPAQGRR--LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL 180 LN IN+N+ LP + + A GWGL R +A L +++ +V Sbjct: 180 LNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGF-LARNLMYVDIPIVDHQ 238 Query: 181 ---------------CRRSNVCTLVRGRQAGVCFGDSGSPLVC------NGLIHGIASFV 219 + +C + C GDSG LV + GI S+ Sbjct: 239 KCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWG 298 Query: 220 RGGCASGLYPDAFAPVAQFVNWIDSII 246 C + V ++ WI++II Sbjct: 299 SMNCGEAGQYGVYTKVINYIPWIENII 325 >1YC0-A nrPDB Length = 283 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 77/278 (27%), Positives = 120/278 (43%), Gaps = 35/278 (12%) Query: 1 MTLGRRLACLFLACVLPALLLGG------TALASEIVGGRRARPHAWPFMVSLQLRGGHF 54 + L L P G T L I+GG + P + P++ ++ + G F Sbjct: 1 VQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI-GDSF 59 Query: 55 CGATLIAPNFVMSAAHCVANVNVRA-VRVVLGAHNLSRREPTRQVFAVQRIFENG----Y 109 C +L+ +V+SAAHC ++ R V VVLG H +R Q F +++ + Sbjct: 60 CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVF 119 Query: 110 DPVNLLNDIVILQLNGS----ATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRN-RG 164 +P +D+V+++L AT + VQ LP G G +C GWG L N G Sbjct: 120 NPS--DHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSG 177 Query: 165 IASVLQELNVTVV-TSLCRR----------SNVCTLVRGRQAGVCFGDSGSPLVCNG--- 210 +S L+E V +V C + +C ++ C GDSG PL C Sbjct: 178 YSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGV 237 Query: 211 -LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 ++GI S+ GC P + VA +V+WI+ I+ Sbjct: 238 AYLYGIISWG-DGCGRLHKPGVYTRVANYVDWINDRIR 274 >4NZQ-A nrPDB Length = 557 Score = 240 bits (614), Expect = 4e-64, Method: Composition-based stats. Identities = 66/269 (24%), Positives = 106/269 (39%), Gaps = 39/269 (14%) Query: 18 ALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV--- 72 L + + IV G A P+ V L + CGA+LI+ +V++AAHC+ Sbjct: 287 ERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYP 346 Query: 73 ---ANVNVRAVRVVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGS 126 N + V +G H+ +R E ++ +++I Y+ NL DI +++L Sbjct: 347 PWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKP 406 Query: 127 ATINANVQVAQLPAQGRR---LGNGVQCLAMGWGLLGR------NRGIASVLQELNVTVV 177 + + LP + L G + GWG L +G SVLQ +N+ +V Sbjct: 407 VAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIV 466 Query: 178 TS-LCRRS--------NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIASFV 219 +C+ S C G++ C GDSG P V GI S+ Sbjct: 467 ERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG 526 Query: 220 RGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GC + V + WI +I + Sbjct: 527 E-GCDRDGKYGFYTHVFRLKKWIQKVIDQ 554 >1ZJK-A nrPDB Length = 403 Score = 239 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 65/267 (24%), Positives = 103/267 (38%), Gaps = 33/267 (12%) Query: 5 RRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNF 64 + L C L A GG +I GG++A+P +P+ V + GG L+ N+ Sbjct: 142 KSLPVCEPVCGLSARTTGG-----QIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNW 194 Query: 65 VMSAAHCVANVNVRAVRVVLGAHNLSRREPT-RQVFAVQRIFENGY-DPVNLLNDIVILQ 122 V++AAH V A + + L R P Q ++ GY NDI +++ Sbjct: 195 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIK 254 Query: 123 LNGSATINANVQVAQLPAQGRR--LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL 180 LN IN+N+ LP + + A GWGL R +A L +++ +V Sbjct: 255 LNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGF-LARNLMYVDIPIVDHQ 313 Query: 181 ---------------CRRSNVCTLVRGRQAGVCFGDSGSPLVC------NGLIHGIASFV 219 + +C + C GDSG LV + GI S+ Sbjct: 314 KCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWG 373 Query: 220 RGGCASGLYPDAFAPVAQFVNWIDSII 246 C + V ++ WI++II Sbjct: 374 SMNCGEAGQYGVYTKVINYIPWIENII 400 >3RP2-A nrPDB Length = 224 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 71/230 (30%), Positives = 109/230 (47%), Gaps = 20/230 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH----FCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG + PH+ P+M L + CG LI+ FV++AAHC R + V+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC----KGREITVILG 56 Query: 86 AHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AH++ +RE T+Q V++ I Y+ V L+DI++L+L + V V LP+ Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSN--------VCTLVRGRQAG 196 + G C A GWG G + L+E+ + ++ VC Sbjct: 117 IHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRA 176 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 GDSG PL+C G+ HGI S+ P F V+ +V WI+++I Sbjct: 177 AFMGDSGGPLLCAGVAHGIVSYGHP---DAKPPAIFTRVSTYVPWINAVI 223 >1FIZ-A nrPDB Length = 263 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 72/252 (28%), Positives = 105/252 (41%), Gaps = 33/252 (13%) Query: 30 IVGGRRARPHAWPFMVSLQ------LRGGHFCGATLIAPNFVMSAAHCVANVNV-RAVRV 82 +VGG A P AWP+MVSLQ R H CG L+ ++V++AAHC N R+ Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 83 VLGAH------NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVA 136 + GA+ N + P ++ F + I Y +NDI ++++ + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 137 QLPAQGRRLGNG-VQCLAMGWGLLGRNRG-IASVLQELNVTVVT-SLC----------RR 183 LP C GWG L + LQE V ++ LC R Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVCNG------LIHGIASFVRGGCASGLYPDAFAPVAQ 237 +NVC + C GDSG PL+C ++ GI S+ GCA P + Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV-GCARAKRPGVYTSTWP 239 Query: 238 FVNWIDSIIQRS 249 ++NWI S I + Sbjct: 240 YLNWIASKIGSN 251 >1MZD-A nrPDB Length = 240 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 72/235 (30%), Positives = 114/235 (48%), Gaps = 19/235 (8%) Query: 29 EIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAV-RVVLGAH 87 EI+GG+ PH+ PFM S+Q G H CG LI P +V++AAHC VVLGAH Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 88 NLSRREPTRQVFAVQRIFE-NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 +LS+ E ++Q +++ + NDI++++L +A +N +V++ + L Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-RSKTSLR 120 Query: 147 NGVQCLAMGWGLLGRNR-GIASVLQELNVTVVT-SLCR------------RSNVCTLVRG 192 +G +C GWG + + L+E+ VTV++ LC + VC Sbjct: 121 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 180 Query: 193 RQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVA-QFVNWIDSII 246 Q C GD+G PL+C G+ H I S C P + + ++ WI S + Sbjct: 181 GQKDSCKGDAGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >2RDL-A nrPDB Length = 226 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 75/233 (32%), Positives = 114/233 (48%), Gaps = 20/233 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRG--GHF--CGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+GG RPHA P+M L++ H C LI NFVM+AAHC R++ V+LG Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAG----RSITVLLG 56 Query: 86 AHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 AHN +E T Q V++ F YD +LNDI++L+L A + V + A+ Sbjct: 57 AHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNS 116 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT--------SLCRRSNVCTLVRGRQAG 196 + G C A+GWG N + LQE+ + ++ + +C + Sbjct: 117 IPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNPKKIRN 176 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 V GDSG PL+C G+ GIAS+V + P F ++ + WI+ I++ + Sbjct: 177 VYKGDSGGPLLCAGIAQGIASYVL---RNAKPPSVFTRISHYRPWINKILREN 226 >1FIW-A nrPDB Length = 290 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 76/267 (28%), Positives = 113/267 (42%), Gaps = 34/267 (12%) Query: 30 IVGGRRARPHAWPFMVSLQ------LRGGHFCGATLIAPNFVMSAAHCVA-NVNVRAVRV 82 I+GG+ A AWP+MVSLQ R H CG +L+ ++++AAHC V R+ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 83 VLGA------HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVA 136 + GA N + P ++ + + I Y + NDI ++++ T + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 137 QLPAQGRRLGNG-VQCLAMGWGLLGRN-RGIASVLQELNVTVVT-SLC----------RR 183 LP C GWG L N R + +LQE V ++ LC R Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVCNG------LIHGIASFVRGGCASGLYPDAFAPVAQ 237 +NVC + C GDSG PL+C ++ GI S+ GCA P + Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARAKRPGVYTSTWS 239 Query: 238 FVNWIDSIIQRSEDNPCPHPRDPDPAS 264 ++NWI S I + + P PAS Sbjct: 240 YLNWIASKIGSTAVHMIQLPTAS-PAS 265 >1KYN-A nrPDB Length = 235 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 81/232 (34%), Positives = 118/232 (50%), Gaps = 21/232 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLR---GGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 I+GGR +RPH+ P+M LQ++ G CG L+ +FV++AAHC + + V LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGS----NINVTLGA 56 Query: 87 HNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 HN+ RRE T+Q +R I Y+ + NDI++LQL+ N NV LP L Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGL 116 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLC--------RRSNVCTLVRGRQAG 196 G C GWG + RG L+E+ + V C R +C R + Sbjct: 117 RPGTLCTVAGWGRVSMRRGT-DTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKA 175 Query: 197 VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GDSG PL+CN + HGI S+ + SG+ P+ F V+ F+ WI + ++ Sbjct: 176 AFKGDSGGPLLCNNVAHGIVSYGKS---SGVPPEVFTRVSSFLPWIRTTMRS 224 >1ELT-A nrPDB Length = 236 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 82/240 (34%), Positives = 121/240 (50%), Gaps = 27/240 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 +VGGR A+P++WP+ +SLQ + G H CG +LI +VM+AAHCV + R RVVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSA--RTWRVVLG 58 Query: 86 AHNLSRREPTRQVFAVQRIFEN---GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG 142 HNL+ E Q+ V +F + D V DI +L+LN A++N+ VQ+A LP Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-----------SLCRRSNVCTLVR 191 + L N C GWG ++ L++ + V S + + VC Sbjct: 119 QILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGG 178 Query: 192 GRQAGVCFGDSGSPLVCN----GLIHGIASFV-RGGCASGLYPDAFAPVAQFVNWIDSII 246 C GDSG PL C +HG+ SFV GC + P F V+ +++W++ I+ Sbjct: 179 ANSG--CNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >2ZKS-A nrPDB Length = 240 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 78/234 (33%), Positives = 116/234 (49%), Gaps = 17/234 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GGR PH+ P+M SLQ G H CG L+ P +V++AAHC+A + +R+VLG H L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQR-MAQLRLVLGLHTL 59 Query: 90 SRREPTRQVFAVQRIFENGYDP-VNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 P I Y P L ND+ +LQL+G + ++ LP++ + + G Sbjct: 60 --DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAG 117 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRR----------SNVCTLVRGRQAGV 197 +C GWGL + ++ VL+EL++ V+ + +C S VC + Sbjct: 118 TRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQAP 177 Query: 198 CFGDSGSPLVCNG--LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 C GDSG PLVC ++ G+ SF C P VA +V+WI + RS Sbjct: 178 CKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRS 231 >2XRC-A nrPDB Length = 565 Score = 233 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 58/265 (21%), Positives = 99/265 (37%), Gaps = 26/265 (9%) Query: 5 RRLACLFLA--CVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAP 62 RR+ L C + + IVGG+RA+ P+ V+++ G CG I Sbjct: 298 RRIKSLLPKLSCGVKNRMHIRRK---RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGG 354 Query: 63 NFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQV--FAVQRIFENGYDPVNLLNDIVI 120 ++++AAHC+ ++ + + R V + + IF Y+ NDI + Sbjct: 355 CWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIAL 414 Query: 121 LQLNGSATINA----NVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTV 176 +++ A +P C+ GWG N + S LQ V + Sbjct: 415 IEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKL 473 Query: 177 VTS--------LCRRSNVCTLVRGRQAGVCFGDSGSPLVCNG-----LIHGIASFVRGGC 223 +++ + C C GDSG PLVC + G+ S+ C Sbjct: 474 ISNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-C 532 Query: 224 ASGLYPDAFAPVAQFVNWIDSIIQR 248 +P + VA + +WI + R Sbjct: 533 GKPEFPGVYTKVANYFDWISYHVGR 557 >3F6U-H nrPDB Length = 240 Score = 233 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 61/241 (25%), Positives = 101/241 (41%), Gaps = 27/241 (11%) Query: 31 VGGRRARPHAWPFMVSLQLRGGHF-CGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 + G+ R P+ V L CGA LI P++V++AAHC+ + V LG ++L Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKK--LLVRLGEYDL 59 Query: 90 SRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG----RR 144 R E ++ +F Y NDI +L L AT++ + LP G Sbjct: 60 RRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAEREL 119 Query: 145 LGNGVQCLAMGWGLLGRNRGIAS-----VLQELNVTVV---------TSLCRRSNVCTLV 190 G + L GWG A VL + + VV +++ + +C + Sbjct: 120 NQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGI 179 Query: 191 RGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 G + C GDSG P+V + + G+ S+ GC + V+++++WI I Sbjct: 180 LGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGE-GCGLLHNYGVYTKVSRYLDWIHGHI 238 Query: 247 Q 247 + Sbjct: 239 R 239 >4XDE-A nrPDB Length = 257 Score = 233 bits (595), Expect = 6e-62, Method: Composition-based stats. Identities = 68/242 (28%), Positives = 98/242 (40%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVN-VRAVRVVLGAHN 88 +VGG A A P++ +L G FC +LIAP +V++AAHC+ + + VVLG Sbjct: 3 VVGGLVALRGAHPYIAALYW-GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 89 LSRREPTRQVFAVQRI-FENGYDPVNLLNDIVILQLNGSAT-----INANVQVAQLPAQG 142 + Q AV+ + PV+ +D+ +L+L A ++ VQ LP+ Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 143 RRLGNGVQCLAMGWGLLGRN-RGIASVLQELNVTVVT-SLCRRS----------NVCTLV 190 R C GWG AS LQE V ++ C +C Sbjct: 122 ARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGF 181 Query: 191 RGRQAGVCFGDSGSPLVCNG-------LIHGIASFVRGGCASGLYPDAFAPVAQFVNWID 243 C GDSG PLVC + GI S+ GC P + VA ++ WI Sbjct: 182 LEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVYTDVAYYLAWIR 240 Query: 244 SI 245 Sbjct: 241 EH 242 >1ETT-H nrPDB Length = 259 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 102/257 (39%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G+ A P+ V L + CGA+LI+ +V++AAHC+ N V + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 82 VVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ + +I Y+ NL DI +L+L ++ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 139 PAQGRR---LGNGVQCLAMGWG------LLGRNRGIASVLQELNVTVVTS-LCRRS---- 184 P + L G + GWG SVLQ +N+ +V +C+ S Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 185 ----NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIASFVRGGCASGLYPDA 231 C G++ C GDSG P V GI S+ GC Sbjct: 181 ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE-GCDRDGKYGF 239 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I R Sbjct: 240 YTHVFRLKKWIQKVIDR 256 >2OCV-B nrPDB Length = 259 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 65/257 (25%), Positives = 102/257 (39%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 82 VVLGAHNLSRREPT-RQVFAVQRIF-ENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ +++I+ Y+ NL DI +L+L + + L Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 139 PAQG---RRLGNGVQCLAMGWGLLGR------NRGIASVLQELNVTVVTS-LCRRS---- 184 P + L G + GWG L N SVLQ +N+ +V +C+ S Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 185 ----NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIASFVRGGCASGLYPDA 231 C ++ C GDSG P V GI S+ GC Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRKGKYGF 239 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I + Sbjct: 240 YTHVFRLKAWIQKVIDQ 256 >2R0L-A nrPDB Length = 248 Score = 232 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 29/243 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRA-VRVVLGAHN 88 I+GG + P + P++ ++ + G FC +L+ +V+SAAHC ++ R V VVLG H Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 89 LSRREPTRQVFAVQRIFENG----YDPVNLLNDIVILQLNGS----ATINANVQVAQLPA 140 +R Q F +++ ++P +D+V+++L AT + VQ LP Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPS--DHDLVLIRLKKKGDRCATRSQFVQPICLPE 117 Query: 141 QGRRLGNGVQCLAMGWGLLGRN-RGIASVLQELNVTVV-TSLCRR----------SNVCT 188 G G +C GWG L N G +S L+E V +V C + +C Sbjct: 118 PGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCA 177 Query: 189 LVRGRQAGVCFGDSGSPLVCNG----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 ++ C GDSG PL C ++GI S+ GC P + VA +V+WI+ Sbjct: 178 GYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHKPGVYTRVANYVDWIND 236 Query: 245 IIQ 247 I+ Sbjct: 237 RIR 239 >1VR1-H nrPDB Length = 261 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 65/261 (24%), Positives = 103/261 (39%), Gaps = 43/261 (16%) Query: 30 IVGGRRARPHAWPFMVSLQLR------GGHFCGATLIAPNFVMSAAHCV------ANVNV 77 IV G A P+ V L + CGA+LI+ +V++AAHC+ N Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 78 RAVRVVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGSATINANVQ 134 + V +G H+ +R E ++ +++I Y+ NL DI +++L + + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 135 VAQLPAQGRR---LGNGVQCLAMGWGLLGR------NRGIASVLQELNVTVVTS-LCRRS 184 LP + L G + GWG L +G SVLQ +N+ +V +C+ S Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 185 --------NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIASFVRGGCASGL 227 C G++ C GDSG P V GI S+ GC Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRDG 239 Query: 228 YPDAFAPVAQFVNWIDSIIQR 248 + V + WI +I + Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQ 260 >2XXL-A nrPDB Length = 408 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 68/292 (23%), Positives = 109/292 (37%), Gaps = 50/292 (17%) Query: 23 GTALASEIVGGRRARPHAWPFMVSLQLR----GGHFCGATLIAPNFVMSAAHCVANVNVR 78 G L+ + G + + P+M L+ + CG +I+ ++++AAHCV + Sbjct: 112 GNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQND 171 Query: 79 AVRVVLGAHNLSRREPTRQ-------------VFAVQRIFENGYDPVNLLNDIVILQLNG 125 + LG H +S E RQ V + + YD ++++DI +L+LN Sbjct: 172 LYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNR 231 Query: 126 SATINANVQVAQLPAQGRRLGNGVQC---LAMGWGLLGRNRGIASVLQELNVTV-----V 177 S +++ LP Q GWG N + VL + NV + Sbjct: 232 SVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTT-ENGSSSDVLLQANVPLQPRSAC 290 Query: 178 TSLCRR----SNVCTLVRGRQAGVCFGDSGSPLVC----------NGLIHGIASFVRGGC 223 + RR S +C G C GDSG PL + GI S C Sbjct: 291 SQAYRRAVPLSQLCVG-GGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTC 349 Query: 224 ASGLYPDAFAPVAQFVNWIDSIIQRS---------EDNPCPHPRDPDPASRT 266 P + V ++V WI + + E P P+P ++RT Sbjct: 350 GQISLPGLYTNVGEYVQWITDTMASNGLLESRGPFEGKPIPNPLLGLDSTRT 401 >1FON-A nrPDB Length = 240 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 77/244 (31%), Positives = 114/244 (46%), Gaps = 30/244 (12%) Query: 32 GGRRARPHAWPFMVSLQLRG----GHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 G A P++W + VSLQ H CG +LIAP++V++A HC++ R +VVLG + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS--RTYQVVLGEY 58 Query: 88 NLSRREPTRQVFAVQR---IFENGYDPV--NLLNDIVILQLNGSATINANVQVAQLPAQG 142 + S E + QV + ++ NDI +++L+ SA + VQ+A LP G Sbjct: 59 DRSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAG 118 Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQELNVT-VVTSLC----------RRSNVCTLVR 191 L N C GWG L + LQ+ + V C +++ VC Sbjct: 119 DILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGD 178 Query: 192 GRQAGVCFGDSGSPLVC-----NGLIHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDSI 245 R C GDSG PL C + +HG+ SFV GC + P F V+ F++WID Sbjct: 179 TRSG--CNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDET 236 Query: 246 IQRS 249 I + Sbjct: 237 IASN 240 >5LHN-A nrPDB Length = 247 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 65/247 (26%), Positives = 97/247 (39%), Gaps = 31/247 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRG------GHFCGATLIAPNFVMSAAHCVANV-NVRAVRV 82 IVGG P+ ++ + CG +LI+P +V SAAHC + V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 83 VLGAHNLSRREPTRQVFAVQRIFENGY---DPVNLLNDIVILQLNGS----ATINANVQV 135 LG S P F V+++ + Y D + NDI +L++ S A + ++Q Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 136 AQLPAQGRRLGNGVQCLAMGWGLLGRNRG-IASVL-----------QELNVTVVTSLCRR 183 LP + G C G+G + L Q + S Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 184 SNVCTLVRGRQAGVCFGDSGSPLVCN----GLIHGIASFVRGGCASGLYPDAFAPVAQFV 239 +C + C GDSG PL+CN + GI S+ R GCA P + V+ F+ Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGR-GCAEKNKPGVYTRVSHFL 239 Query: 240 NWIDSII 246 +WI S I Sbjct: 240 DWIQSHI 246 >5O32-I nrPDB Length = 244 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 54/238 (22%), Positives = 92/238 (38%), Gaps = 21/238 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG+RA+ P+ V+++ G CG I ++++AAHC+ ++ + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 90 SRREPTRQV--FAVQRIFENGYDPVNLLNDIVILQLNGSATINA----NVQVAQLPAQGR 143 + R V + + IF Y+ NDI ++++ A +P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 144 RLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS--------LCRRSNVCTLVRGRQA 195 C+ GWG N + S LQ V ++++ + C Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSI 179 Query: 196 GVCFGDSGSPLVCNG-----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 C GDSG PLVC + G+ S+ C +P + VA + +WI + R Sbjct: 180 DACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHVGR 236 >1AZZ-A nrPDB Length = 226 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 77/226 (34%), Positives = 119/226 (52%), Gaps = 17/226 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG A P++WP +L + +FCG +LI+P ++++AAHC+ V VVLGAHN+ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGF--VDVVLGAHNI 58 Query: 90 SRREPTR-QVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 E T+ + + Y+ + NDI +++L T+ A + LP+ +G G Sbjct: 59 REDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPS--TDVGVG 116 Query: 149 VQCLAMGWGLLGRNR-GIASVLQELNVTVVTSLCRRS--------NVCTLVRGRQAGVCF 199 GWGL + GI+ VL++++V ++++ + N+C + G C Sbjct: 117 TVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNIC-IDSTGGKGTCN 175 Query: 200 GDSGSPLVCNGLIHGIASFV-RGGCASGLYPDAFAPVAQFVNWIDS 244 GDSG PL NGL +GI SF GC YPDAF V F++WI + Sbjct: 176 GDSGGPLNYNGLTYGITSFGAAAGC-EAGYPDAFTRVTYFLDWIQT 220 >1BDA-A nrPDB Length = 265 Score = 227 bits (578), Expect = 6e-60, Method: Composition-based stats. Identities = 58/253 (22%), Positives = 95/253 (37%), Gaps = 35/253 (13%) Query: 29 EIVGGRRARPHAWPFMVSLQLR------GGHFCGATLIAPNFVMSAAHCVANV-NVRAVR 81 I GG A + P+ ++ + CG LI+ +++SAAHC + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 82 VVLGAHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGS----ATINANVQVA 136 V+LG Q F V++ I +D NDI +LQL A ++ V+ Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 137 QLPAQGRRLGNGVQCLAMGWGLLGRNRG-IASVLQELNV-----------TVVTSLCRRS 184 LP +L + +C G+G + L+E +V ++ + Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDN 192 Query: 185 NVCTLVRGRQA------GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAP 234 +C C GDSG PLVC + GI S+ GC P + Sbjct: 193 MLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWG-LGCGQKDVPGVYTK 251 Query: 235 VAQFVNWIDSIIQ 247 V +++WI ++ Sbjct: 252 VTNYLDWIRDNMR 264 >4FXG-H nrPDB Length = 242 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 58/242 (23%), Positives = 95/242 (39%), Gaps = 28/242 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I GG++A+P +P+ V + GG L+ N+V++AAH V A + + L Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 90 SRREPT-RQVFAVQRIFENGY-DPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR--L 145 R P Q ++ GY NDI +++LN IN+N+ LP + + Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL---------------CRRSNVCTLV 190 A GWGL R +A L +++ +V + +C + Sbjct: 119 RTDDIGTASGWGLTQRGF-LARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 177 Query: 191 RGRQAGVCFGDSGSPLVC------NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GD+G LV + GI S+ C + V ++ WI++ Sbjct: 178 ESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIEN 237 Query: 245 II 246 II Sbjct: 238 II 239 >1SC8-U nrPDB Length = 262 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 66/264 (25%), Positives = 98/264 (37%), Gaps = 36/264 (13%) Query: 18 ALLLGGTALASE--IVGGRRARPHAWPFMVSLQLRGG-----HFCGATLIAPNFVMSAAH 70 G L I+GG P+ ++ R + CG +LI+P +V+SA H Sbjct: 2 KFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATH 61 Query: 71 CVANV-NVRAVRVVLGAHNLSRREPTRQVFAVQR-IFENGYDPVN--LLNDIVILQLNGS 126 C + V LG L+ F V+ I Y NDI +L++ Sbjct: 62 CFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSK 121 Query: 127 ----ATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT---- 178 A + +Q LP+ G C G+G N ++L +TVV Sbjct: 122 EGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFG--KENSTDYLYPEQLKMTVVKLISH 179 Query: 179 SLCRRS----------NVCTLVRGRQAGVCFGDSGSPLVC----NGLIHGIASFVRGGCA 224 C++ +C + C GDSG PLVC + GI S+ R GCA Sbjct: 180 RECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGR-GCA 238 Query: 225 SGLYPDAFAPVAQFVNWIDSIIQR 248 P + V+ F+ WI S + Sbjct: 239 LKDKPGVYTRVSHFLPWIRSHTKE 262 >1A5I-A nrPDB Length = 265 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 57/250 (22%), Positives = 94/250 (37%), Gaps = 35/250 (14%) Query: 32 GGRRARPHAWPFMVSLQLRGG------HFCGATLIAPNFVMSAAHCVA-NVNVRAVRVVL 84 GG + P+ ++ + CG LI+ +V++AAHC + ++VVL Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 85 GAHNLSRREPTRQVFAVQR-IFENGYDPVNLLNDIVILQLNGS----ATINANVQVAQLP 139 G + Q F V++ I +D NDI +LQL A + +V+ LP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 140 AQGRRLGNGVQCLAMGWGLLGRNRG-IASVLQELNVT-----------VVTSLCRRSNVC 187 +L + +C G+G + + L+E +V + + +C Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 188 TLVRGRQA------GVCFGDSGSPLVCNG----LIHGIASFVRGGCASGLYPDAFAPVAQ 237 C GDSG PLVC + GI S+ GC P + V Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEKDVPGVYTKVTN 254 Query: 238 FVNWIDSIIQ 247 ++ WI + Sbjct: 255 YLGWIRDNMH 264 >4IW4-E nrPDB Length = 279 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 55/276 (19%), Positives = 101/276 (36%), Gaps = 49/276 (17%) Query: 30 IVGGRRARPHAWPFMVSLQLRG-------GHFCGATLIAPNFVMSAAH---------CVA 73 I+GGR A P +P+ + + F L++ +++++AAH V Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 74 NVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANV 133 V+ V V LG H++ + A + + ++ N +DI ++QL + +V Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 134 QVAQLPA-QGRRLGNGVQCLAMGWGLLGRN-----------RGIASVLQELNVTVV-TSL 180 LP + + L GWG+ N R ++ VLQ + + VV + Sbjct: 121 MPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAE 180 Query: 181 CR-------------RSNVCTLVRGRQAGVCFGDSGSPLV------CNGLIHGIASFVR- 220 C+ + C C GDSG V ++ G+ S+ Sbjct: 181 CKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGP 240 Query: 221 GGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPH 256 C S + V+ +V+W+ + + P Sbjct: 241 EECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEPQ 276 >1EQ9-A nrPDB Length = 222 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 79/228 (34%), Positives = 112/228 (49%), Gaps = 15/228 (6%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVAN-VNVRAVRVVLGAHN 88 IVGG+ A +P+ VSL+L G H CGA+++ N V++AAHCV N+ ++V +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 LS E + YD L ND+ ++ L N VQ +L L + Sbjct: 61 LS--ESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLESN 118 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTV-VTSLCRR-------SNVCTLVRGRQAGVCFG 200 C GWG + LQE+ + V C R S++CTL R G C G Sbjct: 119 -PCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICTLT-KRGEGACHG 176 Query: 201 DSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 DSG PLV NG GI SF CA G PD + V+ FV+WI++ +++ Sbjct: 177 DSGGPLVANGAQIGIVSFGS-PCALGE-PDVYTRVSSFVSWINANLKK 222 >5TO3-B nrPDB Length = 409 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 65/257 (25%), Positives = 102/257 (39%), Gaps = 39/257 (15%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 82 VVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ +++I Y+ NL DI +++L + + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 139 PAQG---RRLGNGVQCLAMGWGLLGR------NRGIASVLQELNVTVVTS-LCRRS---- 184 P + L G + GWG L +G SVLQ +N+ +V +C+ S Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 185 ----NVCTLV---RGRQAGVCFGDSGSPLVCN------GLIHGIASFVRGGCASGLYPDA 231 C G++ C GDSG P V GI S GC Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAG-AGCDRDGKYGF 239 Query: 232 FAPVAQFVNWIDSIIQR 248 + V + WI +I + Sbjct: 240 YTHVFRLKKWIQKVIDQ 256 >5XRF-A nrPDB Length = 242 Score = 218 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 56/241 (23%), Positives = 100/241 (41%), Gaps = 21/241 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHF--CGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 ++GG + F+ + C TLI +V++AAHC R + + LG H Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYK----RGLNIYLGMH 62 Query: 88 NLS-RREPTRQVFAVQRIFENGYDPVNL-LNDIVILQLNGSATINANVQVAQLPAQGRRL 145 N S + + ++ +A++ + + + D+V+L+LN + + ++ Sbjct: 63 NQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS--LPSSPP 120 Query: 146 GNGVQCLAMGWGLLGRNRG-IASVLQELNVTVVTSL-CRRSN---------VCTLVRGRQ 194 G C MGWG++ + + V N+ ++ + C +C V Sbjct: 121 SIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEGG 180 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPC 254 C DSG PL+C+G GI F + CA P + V+ + +WI +II C Sbjct: 181 IDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAGKTTTAC 240 Query: 255 P 255 P Sbjct: 241 P 241 >4BXW-A nrPDB Length = 423 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 61/252 (24%), Positives = 100/252 (39%), Gaps = 31/252 (12%) Query: 29 EIVGGRRARPHAWPFMVSLQL-RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 IV G + P+ +L + G FCG T+++P +V++AAHC+ + VV+G Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINET--ETISVVVGEI 226 Query: 88 NLSRREPTRQVFAVQRIFEN----------GYDPVNLLNDIVILQLNGSATINANVQVAQ 137 + SR E T + +V +I+ + +D DI I+Q+ + NV A Sbjct: 227 DKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPAC 285 Query: 138 LPA---QGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLC--------RRSN 185 LP + L + G+G + + L+ L V V C + Sbjct: 286 LPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNM 345 Query: 186 VCTLVRGRQAGVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNW 241 C C GDSG P I GI S GCA + +++F+ W Sbjct: 346 FCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGE-GCARNGKYGNYTKLSKFIPW 404 Query: 242 IDSIIQRSEDNP 253 I I+++ + Sbjct: 405 IKRIMRQKLPST 416 >1YM0-A nrPDB Length = 238 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 70/242 (28%), Positives = 104/242 (42%), Gaps = 26/242 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG--HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 IVGG ARP+ +P+ VS++ + HFCG ++I +V+ AAHC+ V +V+G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 88 NLSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPA-QGRRL 145 + S RQ V IF N YDP L ND+ +++ + T + NV P + Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDYV 120 Query: 146 GNGVQCLAMGWGLLGRNRG-IASVLQELNVTV----------VTSLCRRSNVCTLVRGR- 193 QC GWG + +VL+ + + + + +C Sbjct: 121 YRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTGM 178 Query: 194 -QAGVCFGDSGSPLVCNG-----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C GDSG PL + GI S+ GCASG YP ++ V WI I Sbjct: 179 TDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWG-IGCASG-YPGVYSRVGFHAGWITDTIT 236 Query: 248 RS 249 + Sbjct: 237 NN 238 >4DJZ-B nrPDB Length = 251 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 58/250 (23%), Positives = 97/250 (38%), Gaps = 38/250 (15%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANV------------- 75 I GR A+ P++ L L G FCG +L+ +++++AAHC+ Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 76 -NVRAVRVVLGAHNLSRREPTRQVFAVQRI-FENGYDPVNLLNDIVILQLNGSATINANV 133 + +++LG H R + Q V+ YDP ND+ +++L S +NA V Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFV 120 Query: 134 QVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR---------- 182 LP ++ G + GWG R L E+ + +V S C+ Sbjct: 121 MPICLPEGPQQ--EGAMVIVSGWGKQFLQR-FPETLMEIEIPIVDHSTCQKAYAPLKKKV 177 Query: 183 -RSNVCTLVRGRQAGVCFGDSGSPLVC------NGLIHGIASFVRGGCASGLYPDAFAPV 235 R +C + C GDSG P+V + G S+ C ++ + Sbjct: 178 TRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD-CGKKDRYGVYSYI 236 Query: 236 AQFVNWIDSI 245 +WI + Sbjct: 237 HHNKDWIQRV 246 >5LPF-A nrPDB Length = 234 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 51/235 (21%), Positives = 96/235 (40%), Gaps = 25/235 (10%) Query: 33 GRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRR 92 G + P+ VSL C L+ ++V++AAHC + + +G +L Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC----GNKPLWARVGDDHLLLL 62 Query: 93 EPTRQVFAVQRIFENGYD--------PVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 + + + + Y +D+++L+L + V+ QLP + + Sbjct: 63 QGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 145 LGNGVQCLAMGWGLLGRNR-GIASVLQELNVTVVT-SLCR--------RSNVCTLVRGRQ 194 G QC GWG R L ++T+++ C + +C R Sbjct: 123 --PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRG 179 Query: 195 AGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 C DSG PLVC+ + GI S+ C S +P + + ++++WI+ +I+ + Sbjct: 180 QDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >2OLG-A nrPDB Length = 278 Score = 211 bits (538), Expect = 3e-55, Method: Composition-based stats. Identities = 59/268 (22%), Positives = 102/268 (38%), Gaps = 43/268 (16%) Query: 20 LLGGTALASEIVGGRRARPHAWPFMVSLQLRGG-----HFCGATLIAPNFVMSAAHCVAN 74 G A +I+ G P +P+ + + CG +LI ++++AAHCVA Sbjct: 13 DCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAG 72 Query: 75 VNVRAV----RVVLGAHNLSRREPTRQVFAV------------QRIFENGYDPVNLL--N 116 +R V +V LG N + V + I Y + + Sbjct: 73 RVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYH 132 Query: 117 DIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTV 176 DI +++LN ++ LP + G + +GWG +++ Q+L V V Sbjct: 133 DIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQKLAVPV 191 Query: 177 VTSL------------CRRSNVCTLVRGRQAGVCFGDSGSPLVCNG-----LIHGIASFV 219 V + R S +C + C GDSG PL+ + G+ SF Sbjct: 192 VHAEQCAKTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFG 250 Query: 220 RGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 C + +P + V ++ +WI+ I+ Sbjct: 251 AT-CGTEGWPGIYTKVGKYRDWIEGNIR 277 >6BQM-A nrPDB Length = 506 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 60/249 (24%), Positives = 103/249 (41%), Gaps = 31/249 (12%) Query: 23 GTALASEIVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCVANVNVRAV 80 + ++S I+GG +A WP+MV+L R FCG + + +V++AAHCV + Sbjct: 4 ESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKG 63 Query: 81 RVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA 140 V+LGA +++ ++ Q N Y ++ NDI +L+L +VQ + Sbjct: 64 DVLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQ-ISDSS 122 Query: 141 QGRRLGNGVQCLAMGWGL----LGRNRGIASVLQELNVTVV---------TSLCRRSN-- 185 L +G+G G A++L ++ V V + ++N Sbjct: 123 DFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYS 182 Query: 186 ------VCTLVRGRQAGVCFGDSGSPLVC---NGLIH-GIASFVRGGCASGLYPDAFAPV 235 C G C GD+G P+ NG G+ S+ GC P + + Sbjct: 183 QLTNNAFCAGSFG--KDACSGDAGGPIFFDSNNGRKQMGVVSWG-DGCGRANSPGVYTNL 239 Query: 236 AQFVNWIDS 244 + F +W+D Sbjct: 240 SVFNDWLDD 248 >4LK4-A nrPDB Length = 357 Score = 208 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 68/242 (28%), Positives = 114/242 (47%), Gaps = 26/242 (10%) Query: 26 LASEIVGGRRARPHAWPFMVSLQLRG-----GHFCGATLIAPNFVMSAAHCVANVNVRAV 80 ++S I+ G A WP +V+L RG G FCG + + +V++AAHC + + +V Sbjct: 7 ISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASV 66 Query: 81 RVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA 140 V++GA++L+ ++ A + Y P NLLNDI I++L ++++ + +A PA Sbjct: 67 DVIIGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSL-PAITLAG-PA 124 Query: 141 QGRRLGNGVQCLAMGWGLLGRNRG--IASVLQELNVTVVT-SLCR------------RSN 185 L GWG+ +++ +LQE++V +V+ SLC+ +N Sbjct: 125 TRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNSTN 184 Query: 186 VCTLVRGRQAGVCFGDSGSPLVCN-GLIH-GIASFVRGGCASGLYPDAFAPVAQFVNWID 243 C C GD+G P+V G GI S+ CA + V+ F +WI Sbjct: 185 FCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWIT 242 Query: 244 SI 245 Sbjct: 243 KH 244 >5KWM-A nrPDB Length = 230 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 64/223 (28%), Positives = 86/223 (38%), Gaps = 19/223 (8%) Query: 30 IVGGRRARPHAWPFMVSLQL-RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IVGG A PF V+L G FCG TL APN V++AAHC + VV G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 89 LSRREPTRQVFAVQRI-FENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR-LG 146 +S E T V V + Y D+ +L L +L Sbjct: 61 MSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAGYA 114 Query: 147 NGVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRS--------NVCTLVRGRQAGV 197 +GWG A LQ+ V V + C+++ VC V Sbjct: 115 PDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVDT 174 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVN 240 C GDSG P+V N + G+ S+ GCA P +A V + + Sbjct: 175 CQGDSGGPMVVNNKLIGVTSWGE-GCARPGKPGVYARVGAYYD 216 >2B9L-A nrPDB Length = 394 Score = 201 bits (512), Expect = 3e-52, Method: Composition-based stats. Identities = 69/272 (25%), Positives = 116/272 (42%), Gaps = 42/272 (15%) Query: 23 GTALASEIVGGR-RARPHAWPFMVSLQLRG--------GHFCGATLIAPNFVMSAAHCV- 72 L +I G A +P+MV++ CG +LIAP+ V++ AHCV Sbjct: 123 ERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVN 182 Query: 73 -ANVNVRAVRVVLGAHN-LSRRE--PTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSAT 128 N+ A+++ G + L+ +E P ++ Q I + ++P ++ND+ +L L+ Sbjct: 183 SYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLV 242 Query: 129 INANVQVAQLPAQGRRLGNGVQCLAMGWGL--LGRNRGIASVLQELNVTVVT-SLCR--- 182 N+ LP Q + + +C A GWG G +++L+++ + V C+ Sbjct: 243 QADNIGTICLPQQSQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADL 301 Query: 183 ------------RSNVCTLVRGRQAGVCFGDSGSPLVCNG-------LIHGIASFVRGGC 223 ++ VC + C GD GSPL C + GI ++ GC Sbjct: 302 RNTRLGLKFVLDQTFVCAG-GEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWG-IGC 359 Query: 224 ASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCP 255 P +A VA F NWID +Q + P Sbjct: 360 GDENVPGVYANVAHFRNWIDQEMQAKGLSTTP 391 >1GPZ-A nrPDB Length = 399 Score = 200 bits (508), Expect = 7e-52, Method: Composition-based stats. Identities = 55/275 (20%), Positives = 99/275 (36%), Gaps = 38/275 (13%) Query: 4 GRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPN 63 G ++ C P + +I+GG++A+ +P+ V + G G L+ Sbjct: 135 GEKIPRCLPVCGKP---VNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDR 189 Query: 64 FVMSAAHCVANVNVR-----AVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLN-- 116 ++++AAH + ++ V LG N+ + Y N Sbjct: 190 WILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFE 249 Query: 117 -DIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVT 175 DI +L+L S T+ N+ LP G+ G+G++ IA L+ + + Sbjct: 250 GDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLP 307 Query: 176 VVT-SLCR-------------RSNVCTLVRGRQAGVCFGDSGS------PLVCNGLIHGI 215 V C ++ C + C GDSG P + GI Sbjct: 308 VANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGI 367 Query: 216 ASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSE 250 S+ GC+ G + V +V+WI ++ + Sbjct: 368 VSWG-IGCSRG--YGFYTKVLNYVDWIKKEMEEED 399 >1MD7-A nrPDB Length = 328 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 54/271 (19%), Positives = 96/271 (35%), Gaps = 38/271 (14%) Query: 4 GRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPN 63 G ++ C P + I+GG++A+ +P+ V + G G L+ Sbjct: 67 GEKIPRCLPVCGKP---VNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDR 121 Query: 64 FVMSAAHCVANVNVR-----AVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLN-- 116 ++++AAH + ++ V LG N+ + Y N Sbjct: 122 WILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFE 181 Query: 117 -DIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVT 175 DI +L+L S T+ N+ LP G+ G+G++ IA L+ + + Sbjct: 182 GDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLP 239 Query: 176 VVT-SLCR-------------RSNVCTLVRGRQAGVCFGDSGS------PLVCNGLIHGI 215 V C ++ C + C GD+G P + GI Sbjct: 240 VANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGI 299 Query: 216 ASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 S+ GC+ G + V +V+WI + Sbjct: 300 VSWG-IGCSRG--YGFYTKVLNYVDWIKKEM 327 >1ELV-A nrPDB Length = 333 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 55/283 (19%), Positives = 88/283 (31%), Gaps = 46/283 (16%) Query: 3 LGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAP 62 LG L C +P I+GG A +P+ V + G LI Sbjct: 59 LGPELPKCVPVCGVPREPFEE---KQRIIGGSDADIKNFPWQVFF---DNPWAGGALINE 112 Query: 63 NFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYD-------PVNLL 115 +V++AAH V + V + SR ++ + G+ N Sbjct: 113 YWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFD 172 Query: 116 NDIVILQLNGSATINANVQVAQLP--AQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELN 173 NDI +++L + V LP + L +G L GWG R A L+ Sbjct: 173 NDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKAAR 231 Query: 174 VTVVT-SLCRR-----------------SNVCTLVRGRQAGVCFGDSGSPLVCNG----- 210 + V C+ + +C + C GDSG Sbjct: 232 LPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKT 290 Query: 211 --LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSED 251 G+ S+ + V +V+WI +Q + Sbjct: 291 KFYAAGLVSWGPQC----GTYGLYTRVKNYVDWIMKTMQENST 329 >1PQ7-A nrPDB Length = 224 Score = 198 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 67/227 (29%), Positives = 97/227 (42%), Gaps = 17/227 (7%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 IVGG A +PF+VS+ GG +CG +L+ N V++AAHCV+ ++ G +L Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG--SL 58 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 149 SR Y N ND+ IL+L+ S N+ A+L A G G Sbjct: 59 SRTSGGITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPVAGS 116 Query: 150 QCLAMGWGLLGRNRGIASV-LQELNVTVVT-SLCR---------RSNVCTLVRGRQAGVC 198 GWG V L ++ V +V+ + CR C V C Sbjct: 117 SATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDSC 176 Query: 199 FGDSGSPLV-CNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 GDSG P+V + + G S+ GCA Y +A V ++ID+ Sbjct: 177 QGDSGGPIVDSSNTLIGAVSWG-NGCARPNYSGVYASVGALRSFIDT 222 >3I77-A nrPDB Length = 230 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 59/233 (25%), Positives = 89/233 (38%), Gaps = 26/233 (11%) Query: 30 IVGGRRARPHAWPFMVSL-QLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAH 87 +VGG RA +PFMV L FCG L A + V++AAHCV+ N ++ G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 88 NLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 +L + V + + + G+ D +++L +++A A + Sbjct: 61 DLQSSSAVK-VRSTKVLQAPGFTKETYGKDWALIKLAQPIN-QPTLKIATTTAYNQ---- 114 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRS----------NVCTLVRG-RQAG 196 G GWG L + NV V+ RS +C Sbjct: 115 GTF-TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTGGVD 173 Query: 197 VCFGDSGSPLVCN-----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 C GDSG P+ + GI S+ GCA YP + V+ F + I S Sbjct: 174 TCQGDSGGPMFRKDNADEWIQVGIVSWGY-GCARPGYPGVYTEVSTFASAIAS 225 >2ASU-B nrPDB Length = 234 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 66/236 (27%), Positives = 104/236 (44%), Gaps = 28/236 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLR-GGHFCGATLIAPNFVMSAAHCVANV--NVRAVRVVLGA 86 +VGG P P+ VSL+ R G HFCG +L+ ++++A C ++ + V LG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 87 --HNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR 144 N EP+ Q V ++ +V+L+L S T+N V + LP + Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSGSQ-----LVLLKLERSVTLNQRVALICLPPEWYV 112 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL---------CRRSNVCTLVRGRQA 195 + G +C GWG +VL + V+++ R S +CT Sbjct: 113 VPPGTKCEIAGWGETKGTGN-DTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPV 171 Query: 196 GVCFGDSGSPLVC----NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 247 G C GD G PL C + ++ GI R CA +P F V+ FV+WI +++ Sbjct: 172 GACEGDYGGPLACFTHNSWVLEGIIIPNRV-CARSRWPAVFTRVSVFVDWIHKVMR 226 >1SI5-H nrPDB Length = 240 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 64/236 (27%), Positives = 101/236 (42%), Gaps = 29/236 (12%) Query: 30 IVGG--RRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 +V G R +MVSL+ R H CG +LI ++V++A C + +++ LG H Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 88 NL--SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 ++ E +QV V ++ Y P +D+V+++L A ++ V LP G + Sbjct: 58 DVHGRGDEKCKQVLNVSQLV---YGPE--GSDLVLMKLARPAVLDDFVSTIDLPNYGSTI 112 Query: 146 GNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLC----------RRSNVCTLVRGRQ 194 C GWG G +L+ ++ ++ C S +C Sbjct: 113 PEKTSCSVYGWGYTGLI-NYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIG 171 Query: 195 AGVCFGDSGSPLVCNG----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 +G C GD G PLVC ++ G+ R GCA P F VA + WI II Sbjct: 172 SGPCEGDYGGPLVCEQHKMRMVLGVIVPGR-GCAIPNRPGIFVRVAYYAKWIHKII 226 >4J1Y-A nrPDB Length = 397 Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats. Identities = 54/283 (19%), Positives = 88/283 (31%), Gaps = 46/283 (16%) Query: 3 LGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAP 62 LG L C +P + +GG A +P+ V + G LI Sbjct: 123 LGPELPKCVPVCGVPREPFEE---KARAIGGSDADIKNFPWQVFF---DNPWAGGALINE 176 Query: 63 NFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYD-------PVNLL 115 +V++AAH V + V + SR ++ + G+ N Sbjct: 177 YWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFD 236 Query: 116 NDIVILQLNGSATINANVQVAQLP--AQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELN 173 NDI +++L + V LP + L +G L GWG R A L+ Sbjct: 237 NDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRT-EKRDRAVRLKAAR 295 Query: 174 VTVVT-SLCRR-----------------SNVCTLVRGRQAGVCFGDSGSPLVCNG----- 210 + V C+ + +C + C GDSG Sbjct: 296 LPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKT 354 Query: 211 --LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSED 251 G+ S+ + V +V+WI +Q + Sbjct: 355 KFYAAGLVSWGPQC----GTYGLYTRVKNYVDWIMKTMQENST 393 >3BEU-A nrPDB Length = 224 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 58/231 (25%), Positives = 90/231 (38%), Gaps = 28/231 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 +VGG RA +PFMV L + CG L A + V++AAHCV+ N ++ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 L + V + + + G+ D +++L +++A A + G Sbjct: 57 LQSSSAVK-VRSTKVLQAPGFTKETYGKDWALIKLAQPIN-QPTLKIATTTAYNQ----G 110 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRS---------NVCTLVRGRQAGVC 198 GWG L + NV V+ CR S +C +Q C Sbjct: 111 TF-TVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDTC 169 Query: 199 FGDSGSPLVCN-----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 GDSG P+ + GI S+ GCA + V+ F + I S Sbjct: 170 QGDSGGPMFRKDNADEWVQVGIVSWGE-GCARKGKYGVYTEVSTFASAIAS 219 >2QY0-B nrPDB Length = 242 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 52/249 (20%), Positives = 92/249 (36%), Gaps = 35/249 (14%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVR-----AVRVVL 84 I+GG++A+ +P+ V + G G L+ ++++AAH + ++ V L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 85 GAHNLSRREPTRQVFAVQRIFENGYDPVNLLN---DIVILQLNGSATINANVQVAQLPAQ 141 G N+ + Y N DI +L+L S T+ N+ LP Sbjct: 59 GHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDN 118 Query: 142 GRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCR-------------RSNVC 187 G+ G+G++ IA L+ + + V C ++ C Sbjct: 119 DTFYDLGLMGYVSGFGVMEEK--IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFC 176 Query: 188 TLVRGRQAGVCFGDSGS------PLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNW 241 + C GDSG P + GI S+ GC+ G + V +V+W Sbjct: 177 AGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG-IGCSRG--YGFYTKVLNYVDW 233 Query: 242 IDSIIQRSE 250 I ++ + Sbjct: 234 IKKEMEEED 242 >3H7T-A nrPDB Length = 235 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 53/236 (22%), Positives = 96/236 (40%), Gaps = 21/236 (8%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GG+++ P+ V + + FCG +++ NFV++AA CV + + G+ Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS--- 57 Query: 90 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINA-NVQVAQLPAQGRRLGNG 148 S R ++I+ Y P+ + N+ +++ ++ + +LP+ Sbjct: 58 SYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPD 117 Query: 149 VQCLAMGWGLLG-RNRGIASVLQELNVTVVT-SLCRRSN-------------VCTLVRGR 193 L GWG ++ + L E N TVV C C Sbjct: 118 TSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEYD 177 Query: 194 QAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + + +GD+G P V NG + G+AS++ + +P F V +V I II Sbjct: 178 ETYIGYGDAGDPAVQNGTLVGVASYISSMPSE--FPSVFLRVGYYVLDIKDIISGK 231 >5UBM-A nrPDB Length = 252 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 50/257 (19%), Positives = 82/257 (31%), Gaps = 43/257 (16%) Query: 29 EIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 I+GG A +P+ V + G LI +V++AAH V + V + Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 89 LSRREPTRQVFAVQRIFENGYD-------PVNLLNDIVILQLNGSATINANVQVAQLP-- 139 SR ++ + G+ N NDI +++L + V LP Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 117 Query: 140 AQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR--------------- 183 + L +G L GWG R A L+ + V C+ Sbjct: 118 SSDYNLMDGDLGLISGWGRT-EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVF 176 Query: 184 --SNVCTLVRGRQAGVCFGDSGSPLVCNG-------LIHGIASFVRGGCASGLYPDAFAP 234 + +C + C GDSG G+ S+ + Sbjct: 177 TPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC----GTYGLYTR 231 Query: 235 VAQFVNWIDSIIQRSED 251 V +V+WI +Q + Sbjct: 232 VKNYVDWIMKTMQENST 248 >2FMJ-A nrPDB Length = 222 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 57/231 (24%), Positives = 89/231 (38%), Gaps = 30/231 (12%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANV-NVRAVRVVLGAHN 88 +VGG RA +PFMV L + CG L A + V++AAHCV+ N ++ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNG 148 L + V + + + GY+ D +++L +++A A + G Sbjct: 57 LQSSSAVK-VRSTKVLQAPGYN--GTGKDWALIKLAQPIN-QPTLKIATTTAYNQ----G 108 Query: 149 VQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRRSN---------VCTLVRGRQAGVC 198 GWG L + NV V+ CR + +C C Sbjct: 109 TF-TVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVDTC 167 Query: 199 FGDSGSPLVCN-----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDS 244 GDSG P+ + GI S+ GCA + V+ F + I S Sbjct: 168 QGDSGGPMFRKDNADEWIQVGIVSWGE-GCARKGKYGVYTEVSTFASAIAS 217 >1M9U-A nrPDB Length = 241 Score = 182 bits (462), Expect = 2e-46, Method: Composition-based stats. Identities = 68/237 (28%), Positives = 101/237 (42%), Gaps = 24/237 (10%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG---HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGA 86 ++GG A P +P+ +S Q + G H CGA+L++ +SA+HCV V +RV+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 87 HNLSRREPTRQVFAVQRIFENGYDPVN--LLNDIVILQLNGSATINANVQVAQLPAQGRR 144 S T+ Y NDI IL L S ++ N+Q A LPA Sbjct: 61 WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNN 120 Query: 145 LGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRSNV------------CTLVR 191 G C+ GWG + +LQ+ ++ V+ T+ C + V C Sbjct: 121 DYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQDP 180 Query: 192 GRQAGVCFGDSGSPLVCNG---LIHGIASFV---RGGCASGLYPDAFAPVAQFVNWI 242 G C GDSG PL C + G+ S+V G YP + V+ ++ WI Sbjct: 181 AGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 >3H7O-A nrPDB Length = 228 Score = 178 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 55/232 (23%), Positives = 94/232 (40%), Gaps = 19/232 (8%) Query: 32 GGRRARPHAWPFMVSLQL---RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 GG + P+ V+++ CG +++ FV++AAHCV + + + + N Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 89 LSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINA-NVQVAQLPAQGRRLGN 147 L +P + V ++ + Y + NDI IL+L+ ++ + A+LP R Sbjct: 62 L-WEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 148 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRSN---------VCTLVRGRQAGV 197 G L G+G L+ +TVV CR C G Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSLES 180 Query: 198 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GD+G P V + G+A++ P+ F V +V+WI II++ Sbjct: 181 --GDAGDPTVQQDTLVGVAAYFPK--RPEGAPEVFTKVGSYVSWIQDIIKKK 228 >2HLC-A nrPDB Length = 230 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 62/234 (26%), Positives = 102/234 (43%), Gaps = 29/234 (12%) Query: 30 IVGGRRARPHAWPFMV----SLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG 85 I+ G A +P+ +LQ + +CG +LI ++++AAHCV AV VV+ Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVH----DAVSVVVY 56 Query: 86 AHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRL 145 + + E V + + I + ++P LND+ ++++ N+Q +LP+ Sbjct: 57 LGSAVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKI-PHVEYTDNIQPIRLPSGEELN 115 Query: 146 GNGVQCL--AMGWGLLGRNRGIASVLQE-LNVTVVTSLCRR---------SNVCTLVRGR 193 GWG + +LQ N+ + C + S +C Sbjct: 116 NKFENIWATVSGWGQSNTD---TVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSD 171 Query: 194 QAGVCFGDSGSPLVCNG--LIHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDS 244 CFGDSG P V + L+ G+ SFV G GC SG P F+ V +++WI Sbjct: 172 GKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESG-KPVGFSRVTSYMDWIQQ 224 >5XW8-A nrPDB Length = 133 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 46/134 (34%), Positives = 68/134 (50%), Gaps = 8/134 (5%) Query: 28 SEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAH 87 +IVGG ++ P+ VSL G HFCG +LI +V+SAAHC + ++V LG H Sbjct: 7 DKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGEH 61 Query: 88 NLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLG 146 N+ E Q +I ++ L NDI++++L+ AT+N+ V LP Sbjct: 62 NIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA--A 119 Query: 147 NGVQCLAMGWGLLG 160 G +CL GWG Sbjct: 120 AGTECLISGWGNTK 133 >2PKA-B nrPDB Length = 152 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 42/152 (27%), Positives = 67/152 (44%), Gaps = 14/152 (9%) Query: 110 DPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRN---RGIA 166 D + +D+++L+L A I V+V +LP Q L G C A GWG + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL--GSTCEASGWGSIEPGPDDFEFP 59 Query: 167 SVLQELNVTVVTSL---------CRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIAS 217 +Q + +T++ + S +C C GDSG PL+CNG+ GI S Sbjct: 60 DEIQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITS 119 Query: 218 FVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + C S P + + +++WID I + Sbjct: 120 WGHTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >3VGC-B nrPDB Length = 131 Score = 166 bits (422), Expect = 8e-42, Method: Composition-based stats. Identities = 48/134 (35%), Positives = 71/134 (52%), Gaps = 5/134 (3%) Query: 30 IVGGRRARPHAWPFMVSLQLRGG-HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHN 88 IV G A P +WP+ VSLQ + G HFCG +LI N+V++AAHC V V VV G + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC--GVTTSDV-VVAGEFD 57 Query: 89 LSRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 147 Q + ++F+N Y+ + + NDI +L+L+ +A+ + V LP+ Sbjct: 58 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAA 117 Query: 148 GVQCLAMGWGLLGR 161 G C+ GWGL Sbjct: 118 GTTCVTTGWGLTRY 131 >2JET-B nrPDB Length = 128 Score = 160 bits (405), Expect = 6e-40, Method: Composition-based stats. Identities = 44/131 (33%), Positives = 64/131 (48%), Gaps = 5/131 (3%) Query: 33 GRRARPHAWPFMVSLQLRGG-HFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSR 91 G A P +WP+ VSLQ + G HFCG +LI+ ++V++AAHC V V VV G + Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC--GVKTSDV-VVAGEFDQGS 57 Query: 92 REPTRQVFAVQRIFE-NGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQ 150 E QV + ++F+ ++ + NDI +L+L A + V LP G Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 151 CLAMGWGLLGR 161 C GWG Sbjct: 118 CATTGWGKTKY 128 >4WJG-C nrPDB Length = 315 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 52/288 (18%), Positives = 87/288 (30%), Gaps = 60/288 (20%) Query: 3 LGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAP 62 +G +L C P I+GG ++P+ + GATLI Sbjct: 47 VGDKLPECEAVCGKPK---NPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINE 103 Query: 63 NFVMSAA------HCVANVNVR---AVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVN 113 ++++ A H + + +G L E + + Y V Sbjct: 104 QWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIE--------KVVLHPNYSQV- 154 Query: 114 LLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELN 173 DI +++L ++N V LP++ G GWG N L+ + Sbjct: 155 ---DIGLIKLKQKVSVNERVMPICLPSKDYA-EVGRVGYVSGWGR-NANFKFTDHLKYVM 209 Query: 174 VTVVT-SLC-------------------------RRSNVCTLVRGRQAGVCFGDSGSPLV 207 + V C C + Q C+GD+GS Sbjct: 210 LPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFA 269 Query: 208 CN------GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + GI SF + CA Y + V +W+ I + Sbjct: 270 VHDLEEDTWYATGILSFDKS-CAVAEY-GVYVKVTSIQDWVQKTIAEN 315 >1RIW-B nrPDB Length = 147 Score = 154 bits (390), Expect = 4e-38, Method: Composition-based stats. Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 14/147 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 82 VVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ +++I Y+ NL DI +++L + + L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 139 PAQGRR---LGNGVQCLAMGWGLLGRN 162 P + L G + GWG L Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 14/150 (9%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G+ A P+ V L + CGA+LI+ +V++AAHC+ N V + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 82 VVLGAHNLSRREPT-RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGSATINANVQVAQL 138 V +G H+ +R E ++ + +I Y+ NL DI +L+L ++ + L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 139 PAQGRR---LGNGVQCLAMGWGLLGRNRGI 165 P + L G + GWG Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTT 150 >4F4O-C nrPDB Length = 347 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 51/288 (17%), Positives = 92/288 (31%), Gaps = 62/288 (21%) Query: 4 GRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPN 63 G +L C P + I+GG ++P+ + GATLI Sbjct: 80 GEKLPECEAVCGKPKNPVDQ---VQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQ 136 Query: 64 FVMSAAHCVANVNVRAVRVVLGAHN----------LSRREPTRQVFAVQRIFENGYDPVN 113 ++++ A + LG N L +Q ++++ + + Sbjct: 137 WLLTTA----------KNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTV 186 Query: 114 LLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELN 173 DI +++L +N V LP++ + G+ GWG N L+ + Sbjct: 187 ---DIGLIKLKQKVPVNERVMPICLPSKDY-VNVGLVGYVSGWGR-NANLNFTEHLKYVM 241 Query: 174 VTVVT-SLC-------------------------RRSNVCTLVRGRQAGVCFGDSGSPLV 207 + V C C + Q C+GD+GS Sbjct: 242 LPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFA 301 Query: 208 CN------GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + GI SF + C + Y + V ++WI + I + Sbjct: 302 VHDKDDDTWYAAGILSFDKS-CRTAEY-GVYVRVTSILDWIQTTIADN 347 >4X0L-C nrPDB Length = 259 Score = 150 bits (379), Expect = 6e-37, Method: Composition-based stats. Identities = 50/278 (17%), Positives = 83/278 (29%), Gaps = 60/278 (21%) Query: 13 ACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAA--- 69 C P I+GG ++P+ + GATLI ++++ A Sbjct: 1 VCGKPK---NPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNL 57 Query: 70 ---HCVANVNVR---AVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQL 123 H + + +G L E + + Y V DI +++L Sbjct: 58 FLNHSENATAKDIAPTLTLYVGKKQLVEIE--------KVVLHPNYSQV----DIGLIKL 105 Query: 124 NGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLC- 181 ++N V LP++ G GWG N L+ + + V C Sbjct: 106 KQKVSVNERVMPICLPSKDYA-EVGRVGYVSGWGR-NANFKFTDHLKYVMLPVADQDQCI 163 Query: 182 ------------------------RRSNVCTLVRGRQAGVCFGDSGSPLVCN------GL 211 C + Q C+GD+GS + Sbjct: 164 RHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWY 223 Query: 212 IHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 GI SF + CA Y + V +W+ I + Sbjct: 224 ATGILSFDKS-CAVAEY-GVYVKVTSIQDWVQKTIAEN 259 >1AKS-B nrPDB Length = 98 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 10/99 (10%) Query: 160 GRNRGIASVLQELNVTVVTSLCRRS---------NVCTLVRGRQAGVCFGDSGSPLVCNG 210 S+LQ L V+++ +S +C C GDSG P+VCNG Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 211 LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + GI S+ GCA P + V +VNWI I + Sbjct: 61 QLQGIVSWGY-GCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >2KAI-A nrPDB Length = 80 Score = 114 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 5/82 (6%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 89 I+GGR ++ P+ V++ CG L+ P +V++AAHC V LG HNL Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHC----KNDNYEVWLGRHNL 56 Query: 90 SRREPTRQVFAV-QRIFENGYD 110 E T Q F V G++ Sbjct: 57 FENENTAQFFGVTADFPHPGFN 78 >2WIN-I nrPDB Length = 507 Score = 110 bits (275), Expect = 8e-25, Method: Composition-based stats. Identities = 43/279 (15%), Positives = 84/279 (30%), Gaps = 82/279 (29%) Query: 39 HAWPFMVSLQL----RGGHFCGATLIAPNFVMSAAHCVA-NVNVRAVRVVLGAHNLSRRE 93 H P+ + + +G C +++ FV++AAHC + +++V +G Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG-------- 283 Query: 94 PTRQVFAVQRI-FENGYD---------PVNLLNDIVILQLNGSATINANVQVAQLP---- 139 ++ ++ + F Y+ P D+ +++L ++ LP Sbjct: 284 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 343 Query: 140 -AQGRRLGNGVQC----------------LAM---------------GWGLLGRNRGIAS 167 + RL C G + Sbjct: 344 TTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNG----DKKGSCER 399 Query: 168 VLQEL----NVTVVTSLCRRSNVCTLVRGRQAG--VCFGDSGSPLVCNG----LIHGIAS 217 Q V ++ + +CT A C GDSG PL+ + + G+ S Sbjct: 400 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 459 Query: 218 FV-RGGC----ASGLYP----DAFAPVAQFVNWIDSIIQ 247 + C P D + Q + W+ +Q Sbjct: 460 WGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 498 >1DLE-A nrPDB Length = 298 Score = 107 bits (267), Expect = 6e-24, Method: Composition-based stats. Identities = 43/279 (15%), Positives = 84/279 (30%), Gaps = 82/279 (29%) Query: 39 HAWPFMVSLQL----RGGHFCGATLIAPNFVMSAAHCVA-NVNVRAVRVVLGAHNLSRRE 93 H P+ + + +G C +++ FV++AAHC + +++V +G Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG-------- 76 Query: 94 PTRQVFAVQRI-FENGYD---------PVNLLNDIVILQLNGSATINANVQVAQLP---- 139 ++ ++ + F Y+ P D+ +++L ++ LP Sbjct: 77 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 136 Query: 140 -AQGRRLGNGVQC----------------LAM---------------GWGLLGRNRGIAS 167 + RL C G + Sbjct: 137 TTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNG----DKKGSCER 192 Query: 168 VLQEL----NVTVVTSLCRRSNVCTLVRGRQAG--VCFGDSGSPLVCNG----LIHGIAS 217 Q V ++ + +CT A C GDSG PL+ + + G+ S Sbjct: 193 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 252 Query: 218 FV-RGGC----ASGLYP----DAFAPVAQFVNWIDSIIQ 247 + C P D + Q + W+ +Q Sbjct: 253 WGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 291 >2I6S-A nrPDB Length = 517 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 45/255 (17%), Positives = 81/255 (31%), Gaps = 60/255 (23%) Query: 24 TALASEI--VGGRRARPHAW---PFMVSLQLRGGHFCGATLIAPNFVMSAAHCV-ANVNV 77 + L I VG A P+ V+++ + C LI+ +V++AAHC + Sbjct: 221 SKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDH 280 Query: 78 RAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLN---------DIVILQLNGSAT 128 RV +G + + ++ + + G+D N DI +L+L Sbjct: 281 SLWRVNVGD---PKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVK 337 Query: 129 INANVQVAQLP---AQGRRL--GNGVQC----------------------------LAMG 155 ++ + + LP L G C L MG Sbjct: 338 MSTHARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMG 397 Query: 156 --WGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLI- 212 W N+T V + +C+ + ++ C G+SG + Sbjct: 398 VEWTSCAEVVSQEKT-MFPNLTDVREVVTDQFLCSGTQEDES-PCKGESGGAVFLERRFR 455 Query: 213 ---HGIASFV-RGGC 223 G+ S+ C Sbjct: 456 FFQVGLVSWGLYNPC 470 >2OK5-A nrPDB Length = 752 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 43/279 (15%), Positives = 84/279 (30%), Gaps = 82/279 (29%) Query: 39 HAWPFMVSLQL----RGGHFCGATLIAPNFVMSAAHCVA-NVNVRAVRVVLGAHNLSRRE 93 H P+ + + +G C +++ FV++AAHC + +++V +G Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG-------- 527 Query: 94 PTRQVFAVQRI-FENGYD---------PVNLLNDIVILQLNGSATINANVQVAQLP---- 139 ++ ++ + F Y+ P D+ +++L ++ LP Sbjct: 528 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 587 Query: 140 -AQGRRLGNGVQC----------------LAM---------------GWGLLGRNRGIAS 167 + RL C G + Sbjct: 588 TTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNG----DKKGSCER 643 Query: 168 VLQEL----NVTVVTSLCRRSNVCTLVRGRQAG--VCFGDSGSPLVCNG----LIHGIAS 217 Q V ++ + +CT A C GDSG PL+ + + G+ S Sbjct: 644 DAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVIS 703 Query: 218 FV-RGGC----ASGLYP----DAFAPVAQFVNWIDSIIQ 247 + C P D + Q + W+ +Q Sbjct: 704 WGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 742 >1EPT-B nrPDB Length = 82 Score = 104 bits (261), Expect = 3e-23, Method: Composition-based stats. Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 78 RAVRVVLGAHNLSRREPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVA 136 ++V LG HN+ E Q +I ++ L NDI++++L+ AT+N+ V Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 137 QLPAQGRRLGNGVQCLAMGWGLLG 160 LP G +CL GWG Sbjct: 61 SLPRSCA--AAGTECLISGWGNTK 82 >3F1S-B nrPDB Length = 283 Score = 93.0 bits (230), Expect = 1e-19, Method: Composition-based stats. Identities = 47/222 (21%), Positives = 75/222 (33%), Gaps = 28/222 (12%) Query: 42 PFMVSLQL-RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFA 100 P+ V L G FCG +I NFV++ A C ++ R + V N + ++P + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITVKTY-FNRTSQDPL-MIKI 120 Query: 101 VQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG---RRLGNGVQCLAMGWG 157 YD ND+ +L+L P + L + L GW Sbjct: 121 THVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWA 180 Query: 158 LLGRN-----RGIASVL-------QELNVTVVTSL-CRRSNVCTLVRGRQAGVCFGDSGS 204 G + L Q LNVTV T C RS+V + + V G Sbjct: 181 RNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRG- 239 Query: 205 PLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 + + G+ + V+++ W I+ Sbjct: 240 ----SWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIM 275 >2HNT-F nrPDB Length = 105 Score = 92.6 bits (229), Expect = 1e-19, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 19/103 (18%) Query: 164 GIASVLQELNVTVVTS-LCRRS--------NVCTLV---RGRQAGVCFGDSGSPLVCN-- 209 G SVLQ +N+ +V +C+ S C G++ C GDSG P V Sbjct: 1 GQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSP 60 Query: 210 ----GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GI S+ GC + V + WI +I + Sbjct: 61 FNNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVIDQ 102 >1BBR-E nrPDB Length = 109 Score = 91.8 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 19/102 (18%) Query: 165 IASVLQELNVTVVTS-LCRRS--------NVCTLV---RGRQAGVCFGDSGSPLVCN--- 209 SVLQ +N+ +V +C+ S C G++ C GDSG P V Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 210 ---GLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQR 248 GI S+ GC + V + WI +I R Sbjct: 66 NNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >3H5C-B nrPDB Length = 317 Score = 90.3 bits (223), Expect = 8e-19, Method: Composition-based stats. Identities = 47/222 (21%), Positives = 75/222 (33%), Gaps = 28/222 (12%) Query: 42 PFMVSLQL-RGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFA 100 P+ V L G FCG +I NFV++ A C ++ R + V N + ++P + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITVKTY-FNRTSQDPL-MIKI 161 Query: 101 VQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQG---RRLGNGVQCLAMGWG 157 YD ND+ +L+L P + L + L GW Sbjct: 162 THVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWA 221 Query: 158 LLGRN-----RGIASVL-------QELNVTVVTSL-CRRSNVCTLVRGRQAGVCFGDSGS 204 G + L Q LNVTV T C RS+V + + V G Sbjct: 222 RNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRG- 280 Query: 205 PLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 246 + + G+ + V+++ W I+ Sbjct: 281 ----SWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >3RU4-E nrPDB Length = 96 Score = 87.6 bits (216), Expect = 5e-18, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 43/99 (43%), Gaps = 16/99 (16%) Query: 164 GIASVLQELNVTVVTSL-CRR--------SNVCTLVRGRQAGVCFGDSGSPLVCN----G 210 LQ+ ++ ++++ C++ + +C G C GDSG PLVC Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASG--VSSCMGDSGGPLVCKKNGAW 58 Query: 211 LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + GI S+ C++ P +A V VNW+ + + Sbjct: 59 TLVGIVSWGSSTCST-STPGVYARVTALVNWVQQTLAAN 96 >2JET-C nrPDB Length = 99 Score = 85.3 bits (210), Expect = 3e-17, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 16/98 (16%) Query: 165 IASVLQELNVTVVTSL-CRRS--------NVCTLVRGRQAGVCFGDSGSPLVCN----GL 211 LQ+ + +V+ C++S C G C GDSG PLVC Sbjct: 5 TPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGASG--VDSCMGDSGGPLVCQKDGVWT 62 Query: 212 IHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRS 249 + GI S+ G C++ P ++ V + W+ I++ + Sbjct: 63 LAGIVSWGSGVCST-STPGVYSRVTALMPWVQQILEAN 99 >2HNT-C nrPDB Length = 70 Score = 83.0 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 8/70 (11%) Query: 30 IVGGRRARPHAWPFMVSLQLRGGH--FCGATLIAPNFVMSAAHCV------ANVNVRAVR 81 IV G A P+ V L + CGA+LI+ +V++AAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 82 VVLGAHNLSR 91 V +G H+ +R Sbjct: 61 VRIGKHSRTR 70 >2HNT-E nrPDB Length = 81 Score = 76.0 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 96 RQVFAVQRI-FENGYD-PVNLLNDIVILQLNGSATINANVQVAQLPAQGRR---LGNGVQ 150 ++ +++I Y+ NL DI +++L + + LP + L G + Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 151 CLAMGWGLLGRN 162 GWG L Sbjct: 63 GRVTGWGNLKET 74 >1P3E-A nrPDB Length = 215 Score = 50.2 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 33/171 (19%), Positives = 58/171 (33%), Gaps = 19/171 (11%) Query: 51 GGHFCGATLIAPNFVMSAAHCVANVNVRAV----RVVLGAHNLSRREPTRQVFAVQRIFE 106 GG C TLIAPN +++ HCV N R+ V G ++ + + + Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSAN--MTEFYVP 85 Query: 107 NGY-DPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGI 165 +GY + D +++ + I V + G G+ + Sbjct: 86 SGYINTGASQYDFAVIKTDT--NIGNTVGYRSIRQVTNL--TGTTIKISGY----PGDKM 137 Query: 166 ASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLV-CNGLIHGI 215 S + + S+ R G+SGS ++ N I G+ Sbjct: 138 RSTGKVSQWEMSGSVTREDTNLAYYT---IDTFSGNSGSAMLDQNQQIVGV 185 >1DUE-A nrPDB Length = 242 Score = 37.1 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 43/118 (36%), Gaps = 13/118 (11%) Query: 47 LQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLG-----AHNLSRREPTRQVFAV 101 + ++G LI N V++ H N +V N + P + + V Sbjct: 49 VFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGE-YEV 107 Query: 102 QRIFENGYDPVNLLNDIVILQLNGS---ATINANVQVAQLPAQGRRLGNGVQCLAMGW 156 + I + + D+ +++L ++ + A++ L +G + +G+ Sbjct: 108 KEILQEPFGAGV---DLALIRLKPDQNGVSLGDKISPAKI-GTSNDLKDGDKLELIGY 161 >2SFA-A nrPDB Length = 191 Score = 36.3 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 25/73 (34%), Gaps = 2/73 (2%) Query: 157 GLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCF--GDSGSPLVCNGLIHG 214 G + G + L VT + + + Q VC GDSG L G Sbjct: 100 GQTVQRSGSTTGLHSGRVTGLNATVNYGGGDIVSGLIQTNVCAEPGDSGGALFAGSTALG 159 Query: 215 IASFVRGGCASGL 227 + S G C +G Sbjct: 160 LTSGGSGNCRTGG 172 >2EA3-A nrPDB Length = 189 Score = 34.8 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 13/28 (46%) Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGL 227 GDSG L+ G+ S G C +G Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >2PFE-A nrPDB Length = 186 Score = 34.4 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 13/28 (46%) Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGL 227 GDSG P + G+ S G C SG Sbjct: 138 GDSGGPWLTGSQAQGVTSGGTGDCRSGG 165 >2SGA-A nrPDB Length = 181 Score = 34.4 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 2/73 (2%) Query: 157 GLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCF--GDSGSPLVCNGLIHG 214 G + G + L+ +VT + + + + Q VC GDSG L G Sbjct: 90 GQAVQRSGSTTGLRSGSVTGLNATVNYGSSGIVYGMIQTNVCAQPGDSGGSLFAGSTALG 149 Query: 215 IASFVRGGCASGL 227 + S G C +G Sbjct: 150 LTSGGSGNCRTGG 162 >2OUA-A nrPDB Length = 188 Score = 34.0 bits (77), Expect = 0.068, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 12/28 (42%) Query: 200 GDSGSPLVCNGLIHGIASFVRGGCASGL 227 GDSG + G+ S G C +G Sbjct: 141 GDSGGSFISGTQAQGVTSGGSGNCRTGG 168 >4FVB-A nrPDB Length = 152 Score = 31.0 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 9/23 (39%), Positives = 11/23 (47%) Query: 200 GDSGSPLVCNGLIHGIASFVRGG 222 GD+G L C + GI S G Sbjct: 110 GDAGGILRCQHGVVGIVSTGGNG 132 >3W95-A nrPDB Length = 171 Score = 31.0 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 9/23 (39%), Positives = 11/23 (47%) Query: 200 GDSGSPLVCNGLIHGIASFVRGG 222 GD+G L C + GI S G Sbjct: 129 GDAGGILRCQHGVVGIVSTGGNG 151 >3FD5-A nrPDB Length = 394 Score = 30.6 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 6/72 (8%) Query: 143 RRLGNGVQCLAMGWGLLGRNRGIASVLQ-EL-----NVTVVTSLCRRSNVCTLVRGRQAG 196 G+G+LG + +A + E+ N+ V+ + S C + G G Sbjct: 258 HTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHG 317 Query: 197 VCFGDSGSPLVC 208 C SG L+C Sbjct: 318 TCPETSGGLLIC 329 >4NCX-A nrPDB Length = 506 Score = 30.6 bits (68), Expect = 0.85, Method: Composition-based stats. Identities = 6/38 (15%), Positives = 16/38 (42%) Query: 118 IVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMG 155 + + Q N T++ ++ +P + ++C G Sbjct: 456 LSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSG 493 >5OJX-A nrPDB Length = 254 Score = 29.4 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 21/42 (50%) Query: 124 NGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGI 165 + A++ V+ + + G+R +G++C+ G G + + Sbjct: 206 SHPASLADYVKRSASSSTGQRFHDGLECMVSGMGQMRSQDSL 247 >2HRV-A nrPDB Length = 142 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 12/29 (41%), Gaps = 1/29 (3%) Query: 194 QAGVCF-GDSGSPLVCNGLIHGIASFVRG 221 G C GD G L+C + GI + Sbjct: 97 GEGPCEPGDCGGKLLCKHGVIGIVTAGGD 125 >2M5T-A nrPDB Length = 142 Score = 28.6 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 14/30 (46%), Gaps = 1/30 (3%) Query: 194 QAGVCF-GDSGSPLVCNGLIHGIASFVRGG 222 G C GD+G L+C + GI + G Sbjct: 96 GEGPCVPGDAGGKLLCRHGVIGIITAGGDG 125 >3LT3-A nrPDB Length = 217 Score = 28.6 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 15/24 (62%), Gaps = 1/24 (4%) Query: 194 QAGVCFGDSGSPLV-CNGLIHGIA 216 +A V GD+G PL+ NG + G+ Sbjct: 155 RADVEQGDAGGPLIDLNGQVLGVV 178 >5XIG-A nrPDB Length = 500 Score = 28.3 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 6/43 (13%), Positives = 13/43 (30%), Gaps = 8/43 (18%) Query: 124 NGSATINANVQVAQLPAQGRRLGNGVQCLAMG--------WGL 158 + + ++ +P + G +C G WG Sbjct: 456 DSEQVMTGAMKTLCIPFDQPPMPEGTKCFYTGKPAKRWTLWGR 498 >4NWK-A nrPDB Length = 219 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 22/75 (29%) Query: 199 FGDSGSPLVC-NGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWI-----DSIIQRSEDN 252 G SG PL+C G GI F C G VA+ V++I ++ ++ Sbjct: 151 KGSSGGPLLCPAGHAVGI--FRAAVCTRG--------VAKAVDFIPVESLETTMRS---- 196 Query: 253 PCPHPRDPDPASRTH 267 P R P + R H Sbjct: 197 --PAIRAPSTSLRPH 209 >5XIP-A nrPDB Length = 498 Score = 27.9 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 4/26 (15%), Positives = 9/26 (34%) Query: 130 NANVQVAQLPAQGRRLGNGVQCLAMG 155 ++ +P + G +C G Sbjct: 460 TGAMKPLCIPFDQPPMPEGTRCFFTG 485 >5JYK-A nrPDB Length = 566 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 14/36 (38%), Gaps = 3/36 (8%) Query: 36 ARPH-AWPFMVSLQLRGGHFCGATLIAPNFVMSAAH 70 P+ + P+ Q G +I V++ AH Sbjct: 110 TEPNFSLPWQRKRQYSSGS--SGFIIGGRRVLTNAH 143 >4FXG-G nrPDB Length = 154 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 6/20 (30%), Positives = 7/20 (35%) Query: 5 RRLACLFLACVLPALLLGGT 24 + L C L A GG Sbjct: 135 KSLPVCEPVCGLSARTTGGR 154 >3TVJ-A nrPDB Length = 86 Score = 27.9 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 6/20 (30%), Positives = 7/20 (35%) Query: 5 RRLACLFLACVLPALLLGGT 24 + L C L A GG Sbjct: 67 KSLPVCEPVCGLSARTTGGR 86 >5ILA-A nrPDB Length = 301 Score = 27.5 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 12/31 (38%), Gaps = 2/31 (6%) Query: 40 AWPFMVSLQLRGGHFCGATLIAPNFVMSAAH 70 + P+ Q G +I V++ AH Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAH 143 >1HPG-A nrPDB Length = 187 Score = 27.1 bits (59), Expect = 9.2, Method: Composition-based stats. Identities = 9/25 (36%), Positives = 11/25 (44%), Gaps = 1/25 (4%) Query: 200 GDSGSPLVCNGLIHGIASFVRGGCA 224 GDSG + GI S GC+ Sbjct: 141 GDSGGAHFAGSVALGIHS-GSSGCS 164 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.158 0.553 Lambda K H 0.267 0.0483 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,933,728 Number of Sequences: 36641 Number of extensions: 518961 Number of successful extensions: 2840 Number of sequences better than 10.0: 192 Number of HSP's better than 10.0 without gapping: 313 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 1386 Number of HSP's gapped (non-prelim): 358 length of query: 267 length of database: 10,336,785 effective HSP length: 95 effective length of query: 172 effective length of database: 6,855,890 effective search space: 1179213080 effective search space used: 1179213080 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (20.6 bits) S2: 59 (27.1 bits)