BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08238 (724 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5FWK-A nrPDB 1479 0.0 2CG9-A nrPDB 820 0.0 3Q6N-A nrPDB 768 0.0 2O1V-A nrPDB 615 e-176 3HJC-A nrPDB 562 e-160 3PRY-A nrPDB 541 e-154 2CGE-A nrPDB 523 e-148 2O1W-A nrPDB 478 e-135 5UCI-A nrPDB 451 e-127 2IOQ-A nrPDB 449 e-126 6B9A-B nrPDB 430 e-121 1Y4U-A nrPDB 429 e-120 5J6L-A nrPDB 427 e-120 2O1T-A nrPDB 418 e-117 5NYI-A nrPDB 414 e-115 1HK7-A nrPDB 402 e-112 1USV-A nrPDB 389 e-108 4GQT-A nrPDB 344 6e-95 2XCM-A nrPDB 338 5e-93 4X9L-A nrPDB 335 3e-92 4XDM-A nrPDB 325 3e-89 3K60-A nrPDB 322 4e-88 3Q5K-A nrPDB 314 8e-86 6CJJ-A nrPDB 310 2e-84 1BGQ-A nrPDB 308 4e-84 3OMU-A nrPDB 308 7e-84 2AKP-A nrPDB 269 3e-72 3PEH-A nrPDB 253 2e-67 2GQ0-A nrPDB 236 4e-62 6D28-A nrPDB 227 2e-59 1YT0-A nrPDB 225 5e-59 1Y6Z-A nrPDB 212 4e-55 2IOR-A nrPDB 191 7e-49 3IED-A nrPDB 186 4e-47 5TTH-B nrPDB 184 8e-47 5F5R-A nrPDB 184 2e-46 4Z1F-A nrPDB 183 2e-46 1SF8-A nrPDB 45 1e-04 1FOK-A nrPDB 32 1.1 2DDU-A nrPDB 31 1.6 5DBX-A nrPDB 30 2.8 3DAK-A nrPDB 30 3.6 4GI8-A nrPDB 30 3.7 1NAR-A nrPDB 30 4.1 4GCZ-A nrPDB 29 5.9 2QU8-A nrPDB 29 6.5 6IGX-B nrPDB 29 7.0 1A41-A nrPDB 29 8.9 >5FWK-A nrPDB Length = 727 Score = 1479 bits (3829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 724/724 (100%), Positives = 724/724 (100%) Query: 1 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 60 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT Sbjct: 4 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 63 Query: 61 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 120 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG Sbjct: 64 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 123 Query: 121 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 180 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK Sbjct: 124 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 183 Query: 181 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 240 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE Sbjct: 184 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 243 Query: 241 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE Sbjct: 244 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 303 Query: 301 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV 360 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV Sbjct: 304 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV 363 Query: 361 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA 420 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA Sbjct: 364 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA 423 Query: 421 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ 480 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ Sbjct: 424 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ 483 Query: 481 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG 540 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG Sbjct: 484 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG 543 Query: 541 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA 600 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA Sbjct: 544 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA 603 Query: 601 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE 660 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE Sbjct: 604 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE 663 Query: 661 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM 720 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM Sbjct: 664 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM 723 Query: 721 EEVD 724 EEVD Sbjct: 724 EEVD 727 >2CG9-A nrPDB Length = 677 Score = 820 bits (2119), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/679 (62%), Positives = 544/679 (80%), Gaps = 7/679 (1%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ETF FQAEI QLMSLIINT YSNKEIFLRELISNASDALDKIRY+SL+DP +L++ +L Sbjct: 4 ETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLF 63 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVG 132 I I P P+++ L + D+GIGMTKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGVG Sbjct: 64 IRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 123 Query: 133 FYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQTE 191 FYS +LVA++V VI+K NDDEQY WES+AGGSFTV D E IGRGT + L LK+DQ E Sbjct: 124 FYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLE 183 Query: 192 YLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIE 251 YLEE+R+KEV+K+HS+F+ YPI L + KE EKE+ E E++ EK++E+K DE+ K + Sbjct: 184 YLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPK 243 Query: 252 DVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTND 311 DEE++ KK ++++E EELNKTKP+WTRNP DITQEEY FYKS++ND Sbjct: 244 LEEVDEEEEKKPKTKKVKEEVQE----IEELNKTKPLWTRNPSDITQEEYNAFYKSISND 299 Query: 312 WEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIP 371 WED L VKHFSVEGQLEFRA+LFIP+RAPFDLFE+KKKKNNIKLYVRRVFI D ++LIP Sbjct: 300 WEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIP 359 Query: 372 EYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYE 431 E+L+F++GVVDSEDLPLN+SREMLQQ+KI+KVIRKNIVKK +E F+E+AED E ++KFY Sbjct: 360 EWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYS 419 Query: 432 AFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESK 491 AFSKN+KLG+HED+ NR L++LLRY++++S DE+TSL++YV+RM E QK+IYYITGES Sbjct: 420 AFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESL 479 Query: 492 EQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKK 551 + V S F++ ++ + FEV+++T+PIDEY QLKEF+GK+LV +TK+ EL E +EEK Sbjct: 480 KAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEKA 538 Query: 552 KMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQAL 611 + E+ ++E L K +KEIL +VEKV +S +L+ +P I T +GW+ANMERIMKAQAL Sbjct: 539 EREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQAL 598 Query: 612 RDNSTMGYMMAKKHLEINPDHPIVETLRQKA-EADKNDKAVKDLVVLLFETALLSSGFSL 670 RD+S YM +KK EI+P PI++ L+++ E DK VKDL LL+ETALL+SGFSL Sbjct: 599 RDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSL 658 Query: 671 EDPQTHSNRIYRMIKLGLG 689 ++P + ++RI R+I LGL Sbjct: 659 DEPTSFASRINRLISLGLN 677 >3Q6N-A nrPDB Length = 448 Score = 768 bits (1983), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/440 (86%), Positives = 417/440 (94%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 TKPIWTRNPDDIT EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF+PRRAPFDLF Sbjct: 3 TKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLF 62 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 EN+KKKNNIKLYVRRVFIMD+C+ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI Sbjct: 63 ENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 122 Query: 405 RKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGD 464 RKN+VKKCLELF+ELAEDKENYKKFYE FSKN+KLGIHEDS NR++LSELLRY+TS SGD Sbjct: 123 RKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGD 182 Query: 465 EMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQ 524 EM SL +Y +RMKE QK IYYITGE+K+QVANSAFVER+RK G EV+YM EPIDEYCVQQ Sbjct: 183 EMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQ 242 Query: 525 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRL 584 LKEF+GK+LVSVTKEGLELPEDEEEKKK EE K KFENLCK+MK+IL+KKVEKV +SNRL Sbjct: 243 LKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRL 302 Query: 585 VSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEA 644 V+SPCCIVTSTYGWTANMERIMKAQALRDNSTMGYM AKKHLEINPDH I+ETLRQKAEA Sbjct: 303 VTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEA 362 Query: 645 DKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAV 704 DKNDK+VKDLV+LL+ETALLSSGFSLEDPQTH+NRIYRMIKLGLGIDED+ A++ +AAV Sbjct: 363 DKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAV 422 Query: 705 PDEIPPLEGDEDASRMEEVD 724 +E+PPLEGD+D SRMEEVD Sbjct: 423 TEEMPPLEGDDDTSRMEEVD 442 >2O1V-A nrPDB Length = 666 Score = 615 bits (1586), Expect = e-176, Method: Compositional matrix adjust. Identities = 326/701 (46%), Positives = 452/701 (64%), Gaps = 63/701 (8%) Query: 5 VHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSK 64 V G E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + Sbjct: 15 VPRGSHMSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENA 74 Query: 65 LDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAG 120 L +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 75 LAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDG 134 Query: 121 ADIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRG 178 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GRG Sbjct: 135 QSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSN-EFSVIADPRGNTLGRG 193 Query: 179 TKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKE 238 T + L LKE+ ++YLE +K +VKK+SQFI +PI ++ Sbjct: 194 TTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVW---------------------- 231 Query: 239 EEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQ 298 S + GK D E +N KPIW R ++ Sbjct: 232 ----------------SSKTGGGGK-----------TVWDWELMNDIKPIWQRPSKEVED 264 Query: 299 EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFE--NKKKKNNIKLY 356 +EY FYKS + + +D +A HF+ EG++ F+++LF+P AP LF+ KK + IKLY Sbjct: 265 DEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLY 324 Query: 357 VRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELF 416 VRRVFI D +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK +V+K L++ Sbjct: 325 VRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMI 384 Query: 417 SELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRM 476 ++A++K N F++ F N+KLG+ ED +NR RL++LLR+ +S ++TSL +YV RM Sbjct: 385 KKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDITSLDQYVERM 443 Query: 477 KETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSV 536 KE Q IY++ G S+++ +S FVER+ K+G+EV+Y+TEP+DEYC+Q L EFDGK +V Sbjct: 444 KEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNV 503 Query: 537 TKEGLELPEDEEEKKKMEESKAKFENLCKLMKE-ILDKKVEKVTISNRLVSSPCCIVTST 595 KEG++ E E+ K+ E + +FE L MK+ L K+EK +S RL SPC +V S Sbjct: 504 AKEGVKFDESEKTKESREAIEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQ 563 Query: 596 YGWTANMERIMKAQAL---RDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVK 652 YGW+ NMERIMKAQA +D ST Y KK EINP HP+++ + ++ + D++DK V Sbjct: 564 YGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKEDEDDKTVS 623 Query: 653 DLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDED 693 DL V+LFETA L SG+ L D + + +RI RM++L L ID D Sbjct: 624 DLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPD 664 >3HJC-A nrPDB Length = 444 Score = 562 bits (1448), Expect = e-160, Method: Compositional matrix adjust. Identities = 262/406 (64%), Positives = 343/406 (84%) Query: 286 KPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFE 345 KP+WTR+P D+T+EEY FYK+++NDWED A KHFSVEGQLEFR+++F+P+RAPFD+FE Sbjct: 20 KPLWTRDPKDVTKEEYAAFYKAISNDWEDPAATKHFSVEGQLEFRSIMFVPKRAPFDMFE 79 Query: 346 NKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIR 405 KK+NNIKLYVRRVFIMD+C++L P++L F++GVVDSEDLPLNISRE LQQ+KILKVIR Sbjct: 80 PNKKRNNIKLYVRRVFIMDNCEDLCPDWLGFVKGVVDSEDLPLNISRENLQQNKILKVIR 139 Query: 406 KNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDE 465 KNIVKKCLE+F E+AE+KE+YK+FYE F KN+KLGIHED+ NR++L ELLR+++++SG+E Sbjct: 140 KNIVKKCLEMFDEVAENKEDYKQFYEQFGKNIKLGIHEDTANRKKLMELLRFYSTESGEE 199 Query: 466 MTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQL 525 MT+L +YV+RMK QKSIYYITG+SK+++ S F+E+ R+RG EV++MTEPIDEY +QQ+ Sbjct: 200 MTTLKDYVTRMKAGQKSIYYITGDSKKKLETSPFIEQARRRGLEVLFMTEPIDEYVMQQV 259 Query: 526 KEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLV 585 K+F+ K +TKEG+ E EEEK++ EE KA E LCK MKE+L KVEKV +S RL Sbjct: 260 KDFEDKKFACLTKEGVHFEESEEEKQQREEEKAACEKLCKTMKEVLGDKVEKVIVSERLS 319 Query: 586 SSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD 645 +SPC +VTS +GW+A+ME+IM+ QALRD+S YMM+KK +E+NP HPI++ LR++ AD Sbjct: 320 TSPCILVTSEFGWSAHMEQIMRNQALRDSSMAQYMMSKKTMELNPRHPIIKELRRRVGAD 379 Query: 646 KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGID 691 +NDKAVKDLV LLF+T+LL+SGF LEDP ++ RI RMIKLGL +D Sbjct: 380 ENDKAVKDLVFLLFDTSLLTSGFQLEDPTGYAERINRMIKLGLSLD 425 >3PRY-A nrPDB Length = 268 Score = 541 bits (1393), Expect = e-154, Method: Compositional matrix adjust. Identities = 261/263 (99%), Positives = 262/263 (99%) Query: 284 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 343 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL Sbjct: 2 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 61 Query: 344 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 403 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV Sbjct: 62 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 121 Query: 404 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 463 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG Sbjct: 122 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 181 Query: 464 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 523 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ Sbjct: 182 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 241 Query: 524 QLKEFDGKSLVSVTKEGLELPED 546 QLKEFDGKSLVSVTKEGLEL E+ Sbjct: 242 QLKEFDGKSLVSVTKEGLELAEN 264 >2CGE-A nrPDB Length = 405 Score = 523 bits (1347), Expect = e-148, Method: Compositional matrix adjust. Identities = 253/406 (62%), Positives = 330/406 (81%), Gaps = 2/406 (0%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 TKP+WTRNP DITQEEY FYKS++NDWED L VKHFSVEGQLEFRA+LFIP+RAPFDLF Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 E+KKKKNNIKLYVRRVFI D ++LIPE+L+F++GVVDSEDLPLN+SREMLQQ+KI+KVI Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 405 RKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGD 464 RKNIVKK +E F+E+AED E ++KFY AFSKN+KLG+HED+ NR L++LLRY++++S D Sbjct: 121 RKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVD 180 Query: 465 EMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQ 524 E+TSL++YV+RM E QK+IYYITGES + V S F++ ++ + FEV+++T+PIDEY Q Sbjct: 181 ELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQ 240 Query: 525 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRL 584 LKEF+GK+LV +TK+ EL E +EEK + E+ ++E L K +KEIL +VEKV +S +L Sbjct: 241 LKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKL 299 Query: 585 VSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKA-E 643 + +P I T +GW+ANMERIMKAQALRD+S YM +KK EI+P PI++ L+++ E Sbjct: 300 LDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDE 359 Query: 644 ADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLG 689 DK VKDL LL+ETALL+SGFSL++P + ++RI R+I LGL Sbjct: 360 GGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLN 405 >2O1W-A nrPDB Length = 506 Score = 478 bits (1229), Expect = e-135, Method: Compositional matrix adjust. Identities = 253/543 (46%), Positives = 351/543 (64%), Gaps = 59/543 (10%) Query: 5 VHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSK 64 V G E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + Sbjct: 15 VPRGSHMSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENA 74 Query: 65 LDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAG 120 L +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 75 LAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDG 134 Query: 121 ADIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRG 178 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GRG Sbjct: 135 QSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSN-EFSVIADPRGNTLGRG 193 Query: 179 TKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKE 238 T + L LKE+ ++YLE +K +VKK+SQFI +PI ++ Sbjct: 194 TTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVW---------------------- 231 Query: 239 EEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQ 298 S + GK D E +N KPIW R ++ Sbjct: 232 ----------------SSKTGGGGK-----------TVWDWELMNDIKPIWQRPSKEVED 264 Query: 299 EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFE--NKKKKNNIKLY 356 +EY FYKS + + +D +A HF+ EG++ F+++LF+P AP LF+ KK + IKLY Sbjct: 265 DEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLY 324 Query: 357 VRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELF 416 VRRVFI D +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK +V+K L++ Sbjct: 325 VRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMI 384 Query: 417 SELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRM 476 ++A++K N F++ F N+KLG+ ED +NR RL++LLR+ +S ++TSL +YV RM Sbjct: 385 KKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDITSLDQYVERM 443 Query: 477 KETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSV 536 KE Q IY++ G S+++ +S FVER+ K+G+EV+Y+TEP+DEYC+Q L EFDGK +V Sbjct: 444 KEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNV 503 Query: 537 TKE 539 KE Sbjct: 504 AKE 506 >5UCI-A nrPDB Length = 220 Score = 451 bits (1159), Expect = e-127, Method: Compositional matrix adjust. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 1 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 60 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT Sbjct: 3 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 62 Query: 61 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 120 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG Sbjct: 63 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 122 Query: 121 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 180 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK Sbjct: 123 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 182 Query: 181 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE 218 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE Sbjct: 183 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE 220 >2IOQ-A nrPDB Length = 624 Score = 449 bits (1155), Expect = e-126, Method: Compositional matrix adjust. Identities = 265/684 (38%), Positives = 404/684 (59%), Gaps = 78/684 (11%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL+ Sbjct: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFG 130 + + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 Query: 131 VGFYSAYLVAEKVVVITKHNDDEQ---YAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187 VGFYSA++VA+KV V T+ ++ WES+ G +TV E RGT++ LHL+E Sbjct: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKE--DRGTEITLHLRE 182 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEK 247 + E+L++ RV+ ++ K+S I P+ + EK EE Sbjct: 183 GEDEFLDDWRVRSIISKYSDHIALPVEI--------------------EKREE------- 215 Query: 248 PKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKS 307 K E I E++NK + +WTRN +IT EEY EFYK Sbjct: 216 -----------------------KDGETVISWEKINKAQALWTRNKSEITDEEYKEFYKH 252 Query: 308 LTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCD 367 + +D+ D L H VEG+ E+ +LL+IP +AP+D++ N+ K+ +KLYV+RVFIMD + Sbjct: 253 IAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW-NRDHKHGLKLYVQRVFIMDDAE 311 Query: 368 ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA-EDKENY 426 + +P YL F+RG++DS DLPLN+SRE+LQ S + + +R + K+ L++ +LA +D E Y Sbjct: 312 QFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKY 371 Query: 427 KKFYEAFSKNLKLGIHEDSTNRRRLSELLRY---HTSQSGDEMTSLSEYVSRMKETQKSI 483 + F++ F LK G ED N+ +++LLR+ HT S + SL +YVSRMKE Q+ I Sbjct: 372 QTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSA-QTVSLEDYVSRMKEGQEKI 430 Query: 484 YYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK--EGL 541 YYIT +S +S +E +RK+G EV+ +++ IDE+ + L EFDGK SV+K E L Sbjct: 431 YYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESL 490 Query: 542 ELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTAN 601 E DE ++ E KA +K +L ++V+ V +++RL +P + T + Sbjct: 491 EKLADEVDESAKEAEKA-LTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQ 549 Query: 602 MERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKA-VKDLVVLLFE 660 M ++ A A + + Y+ E+NPDH +V K AD D+A + V LL + Sbjct: 550 MAKLFAA-AGQKVPEVKYI-----FELNPDHVLV-----KRAADTEDEAKFSEWVELLLD 598 Query: 661 TALLSSGFSLEDPQTHSNRIYRMI 684 ALL+ +LEDP R+ +++ Sbjct: 599 QALLAERGTLEDPNLFIRRMNQLL 622 >6B9A-B nrPDB Length = 256 Score = 430 bits (1106), Expect = e-121, Method: Compositional matrix adjust. Identities = 210/236 (88%), Positives = 222/236 (94%), Gaps = 5/236 (2%) Query: 1 MPEEVHHG-----EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIR 55 MPEE EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIR Sbjct: 21 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 80 Query: 56 YESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFME 115 YESLTDPSKLDSGKEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAKSGTKAFME Sbjct: 81 YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 140 Query: 116 ALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPI 175 ALQAGADISMIGQFGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+ Sbjct: 141 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 200 Query: 176 GRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231 GRGTKVILHLKEDQTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAE Sbjct: 201 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAE 256 >1Y4U-A nrPDB Length = 559 Score = 429 bits (1103), Expect = e-120, Method: Compositional matrix adjust. Identities = 241/607 (39%), Positives = 366/607 (60%), Gaps = 66/607 (10%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL+ Sbjct: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFG 130 + + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 Query: 131 VGFYSAYLVAEKVVVITKHNDDE---QYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187 VGFYSA++VA+KV V T+ ++ WES+ G +TV E RGT++ LHL+E Sbjct: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLRE 182 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEK 247 + E+L++ RV+ ++ K+S I P+ + EK EE Sbjct: 183 GEDEFLDDWRVRSIISKYSDHIALPVEI--------------------EKREE------- 215 Query: 248 PKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKS 307 K E I E++NK + +WTRN +IT EEY EFYK Sbjct: 216 -----------------------KDGETVISWEKINKAQALWTRNKSEITDEEYKEFYKH 252 Query: 308 LTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCD 367 + +D+ D L H VEG+ E+ +LL+IP +AP+D++ N+ K+ +KLYV+RVFIMD + Sbjct: 253 IAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW-NRDHKHGLKLYVQRVFIMDDAE 311 Query: 368 ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA-EDKENY 426 + +P YL F+RG++DS DLPLN+SRE+LQ S + + +R + K+ L++ +LA +D E Y Sbjct: 312 QFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKY 371 Query: 427 KKFYEAFSKNLKLGIHEDSTNRRRLSELLRY---HTSQSGDEMTSLSEYVSRMKETQKSI 483 + F++ F LK G ED N+ +++LLR+ HT S + SL +YVSRMKE Q+ I Sbjct: 372 QTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSA-QTVSLEDYVSRMKEGQEKI 430 Query: 484 YYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK--EGL 541 YYIT +S +S +E +RK+G EV+ +++ IDE+ + L EFDGK SV+K E L Sbjct: 431 YYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESL 490 Query: 542 ELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTAN 601 E DE ++ E KA +K +L ++V+ V +++RL +P + T + Sbjct: 491 EKLADEVDESAKEAEKA-LTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQ 549 Query: 602 MERIMKA 608 M ++ A Sbjct: 550 MAKLFAA 556 >5J6L-A nrPDB Length = 228 Score = 427 bits (1099), Expect = e-120, Method: Compositional matrix adjust. Identities = 205/223 (91%), Positives = 217/223 (97%) Query: 9 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSG 68 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRYESLTDPSKLDSG Sbjct: 6 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSG 65 Query: 69 KELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQ 128 KEL I++IPN Q+RTLT+VDTGIGMTKADLINN GTIAKSGTKAFMEALQAGADISMIGQ Sbjct: 66 KELHINLIPNKQDRTLTIVDTGIGMTKADLINNAGTIAKSGTKAFMEALQAGADISMIGQ 125 Query: 129 FGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKED 188 FGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+GRGTKVILHLKED Sbjct: 126 FGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKED 185 Query: 189 QTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231 QTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAE Sbjct: 186 QTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAE 228 >2O1T-A nrPDB Length = 450 Score = 418 bits (1074), Expect = e-117, Method: Compositional matrix adjust. Identities = 203/418 (48%), Positives = 291/418 (69%), Gaps = 7/418 (1%) Query: 282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPF 341 +N KPIW R ++ +EY FYKS + + +D +A HF+ EG++ F+++LF+P AP Sbjct: 21 MNDIKPIWQRPSKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPR 80 Query: 342 DLFE--NKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSK 399 LF+ KK + IKLYVRRVFI D +++P+YLNF++GVVDS+DLPLN+SRE LQQ K Sbjct: 81 GLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHK 140 Query: 400 ILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHT 459 +LKVIRK +V+K L++ ++A++K N F++ F N+KLG+ ED +NR RL++LLR+ + Sbjct: 141 LLKVIRKKLVRKTLDMIKKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQS 199 Query: 460 SQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDE 519 S ++TSL +YV RMKE Q IY++ G S+++ +S FVER+ K+G+EV+Y+TEP+DE Sbjct: 200 SHHPSDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDE 259 Query: 520 YCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKE-ILDKKVEKV 578 YC+Q L EFDGK +V KEG++ E E+ K+ E + +FE L MK+ L K+EK Sbjct: 260 YCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAIEKEFEPLLNWMKDKALKDKIEKA 319 Query: 579 TISNRLVSSPCCIVTSTYGWTANMERIMKAQAL---RDNSTMGYMMAKKHLEINPDHPIV 635 +S RL SPC +V S YGW+ NMERIMKAQA +D ST Y KK EINP HP++ Sbjct: 320 VVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLI 379 Query: 636 ETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDED 693 + + ++ + D++DK V DL V+LFETA L SG+ L D + + +RI RM++L L ID D Sbjct: 380 KDMLRRVKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPD 437 >5NYI-A nrPDB Length = 229 Score = 414 bits (1063), Expect = e-115, Method: Compositional matrix adjust. Identities = 190/223 (85%), Positives = 217/223 (97%) Query: 9 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSG 68 EEEVETFAFQAEIAQLM+LIINTFY+NKEIFLRELI+N +DALDKIRYE+LTDP+KLD+G Sbjct: 7 EEEVETFAFQAEIAQLMTLIINTFYTNKEIFLRELITNTTDALDKIRYETLTDPTKLDTG 66 Query: 69 KELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQ 128 KEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAK+GTKAFMEALQAGADI+MIGQ Sbjct: 67 KELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKTGTKAFMEALQAGADITMIGQ 126 Query: 129 FGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKED 188 FGVGFY+AYLVAEKV VITKHNDDEQYAWE++AGG+FTVR D GEP+GRGTKVILHLKED Sbjct: 127 FGVGFYTAYLVAEKVTVITKHNDDEQYAWETTAGGTFTVRTDTGEPMGRGTKVILHLKED 186 Query: 189 QTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231 QTEYLEERR+KE+VKKH+QFIGYPITL++E+ER+KE++DDEAE Sbjct: 187 QTEYLEERRIKEIVKKHTQFIGYPITLFVEEERDKEVTDDEAE 229 >1HK7-A nrPDB Length = 288 Score = 402 bits (1034), Expect = e-112, Method: Compositional matrix adjust. Identities = 190/287 (66%), Positives = 244/287 (85%), Gaps = 1/287 (0%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 TKP+WTRNP DITQEEY FYKS++NDWED L VKHFSVEGQLEFRA+LFIP+RAPFDLF Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 E+KKKKNNIKLYVRRVFI D ++LIPE+L+F++GVVDSEDLPLN+SREMLQQ+KI+KVI Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 405 RKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGD 464 RKNIVKK +E F+E+AED E ++KFY AFSKN+KLG+HED+ NR L++LLRY++++S D Sbjct: 121 RKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVD 180 Query: 465 EMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQ 524 E+TSL++YV+RM E QK+IYYITGES + V S F++ ++ + FEV+++T+PIDEY Q Sbjct: 181 ELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQ 240 Query: 525 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEIL 571 LKEF+GK+LV +TK+ EL E +EEK + E+ ++E L K +KEIL Sbjct: 241 LKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEIL 286 >1USV-A nrPDB Length = 260 Score = 389 bits (998), Expect = e-108, Method: Compositional matrix adjust. Identities = 177/256 (69%), Positives = 225/256 (87%) Query: 284 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 343 KTKP+WTRNP DITQEEY FYKS++NDWED L VKHFSVEGQLEFRA+LFIP+RAPFDL Sbjct: 2 KTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDL 61 Query: 344 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 403 FE+KKKKNNIKLYVRRVFI D ++LIPE+L+F++GVVDSEDLPLN+SREMLQQ+KI+KV Sbjct: 62 FESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKV 121 Query: 404 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 463 IRKNIVKK +E F+E+AED E ++KFY AFSKN+KLG+HED+ NR L++LLRY++++S Sbjct: 122 IRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSV 181 Query: 464 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 523 DE+TSL++YV+RM E QK+IYYITGES + V S F++ ++ + FEV+++T+PIDEY Sbjct: 182 DELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFT 241 Query: 524 QLKEFDGKSLVSVTKE 539 QLKEF+GK+LV +TK+ Sbjct: 242 QLKEFEGKTLVDITKD 257 >4GQT-A nrPDB Length = 227 Score = 344 bits (883), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 161/206 (78%), Positives = 188/206 (91%) Query: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69 E ETFAFQAEIAQLMSLIINTFYSNKEI+LRELISNASDALDKIRY++LT+PS+LD+GK Sbjct: 6 ENAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGK 65 Query: 70 ELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQF 129 EL I I PN +E+TLT++DTGIGMTKADL+NNLGTIAKSGTKAFMEALQAGADISMIGQF Sbjct: 66 ELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQF 125 Query: 130 GVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQ 189 GVGFYSA+LVA+KVVV +K+NDD+ Y WESSAGGSF VR + + RGTK+++H+KEDQ Sbjct: 126 GVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQ 185 Query: 190 TEYLEERRVKEVVKKHSQFIGYPITL 215 ++LEER++KE+VKKHSQFIGYPI L Sbjct: 186 IDFLEERKIKEIVKKHSQFIGYPIKL 211 >2XCM-A nrPDB Length = 214 Score = 338 bits (867), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 162/212 (76%), Positives = 185/212 (87%), Gaps = 1/212 (0%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 H E ETFAFQAEI QL+SLIINTFYSNKEIFLRELISN+SDALDKIR+ESLTD SKL Sbjct: 2 HAAATETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKL 61 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISM 125 D+ EL I IIP+ TLT+VD+GIGMTK+DL+NNLGTIA+SGTK FMEAL AGAD+SM Sbjct: 62 DAQPELFIHIIPDKATSTLTIVDSGIGMTKSDLVNNLGTIARSGTKEFMEALAAGADVSM 121 Query: 126 IGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILH 184 IGQFGVGFYSAYLVAE+VVV TKHNDDEQY WES AGGSFTV D GE +GRGTK++L+ Sbjct: 122 IGQFGVGFYSAYLVAERVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKMVLY 181 Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGYPITLY 216 LK+DQ EYLEERR+K++VKKHS+FI YPI+L+ Sbjct: 182 LKDDQMEYLEERRIKDLVKKHSEFISYPISLW 213 >4X9L-A nrPDB Length = 250 Score = 335 bits (860), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 160/213 (75%), Positives = 186/213 (87%), Gaps = 1/213 (0%) Query: 11 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKE 70 E ETFAFQAEI QL+SLIINTFYSNKEIFLRELISN+SDALDKIR+ESLTD SKLD+ E Sbjct: 38 ETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPE 97 Query: 71 LKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG 130 L I I+P+ TL+++D+G+GMTK+DL+NNLGTIA+SGTK FMEAL AGAD+SMIGQFG Sbjct: 98 LFIHIVPDKASNTLSIIDSGVGMTKSDLVNNLGTIARSGTKEFMEALAAGADVSMIGQFG 157 Query: 131 VGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQ 189 VGFYSAYLVAE+VVV TKHNDDEQY WES AGGSFTV D GE +GRGTK+ L+LK+DQ Sbjct: 158 VGFYSAYLVAERVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKITLYLKDDQ 217 Query: 190 TEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 222 EYLEERR+K++VKKHS+FI YPI+L+ EK E Sbjct: 218 LEYLEERRLKDLVKKHSEFISYPISLWTEKTTE 250 >4XDM-A nrPDB Length = 259 Score = 325 bits (834), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 154/215 (71%), Positives = 184/215 (85%), Gaps = 1/215 (0%) Query: 9 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSG 68 E +VE F FQAEI QLMSLIINTFYSNKE+FLRELISNASDALDKIRY+SLTD S L+S Sbjct: 39 ESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESK 98 Query: 69 KELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG-ADISMIG 127 EL+I IIP+ +TLTL+D+GIGMTK D++ NLGTIA+SGTK FME LQ+G ADISMIG Sbjct: 99 TELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIG 158 Query: 128 QFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187 QFGVGFYSAYLVA+ V+V +K+NDDEQY WESSAGG FT+ DH EP+GRGTK++LH+KE Sbjct: 159 QFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKE 218 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 222 DQ +YL+E ++K +VKKHS+FI YPI+L KE+E Sbjct: 219 DQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEKE 253 >3K60-A nrPDB Length = 223 Score = 322 bits (824), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 157/208 (75%), Positives = 178/208 (85%), Gaps = 1/208 (0%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ETFAF A+I QLMSLIINTFYSNKEIFLRELISNASDALDKIRYES+TD KL + E Sbjct: 4 ETFAFNADIRQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESITDTQKLSAEPEFF 63 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVG 132 I IIP+ TLT+ D+GIGMTK DLINNLGTIA+SGTKAFMEA+QA DISMIGQFGVG Sbjct: 64 IRIIPDKTNNTLTIEDSGIGMTKNDLINNLGTIARSGTKAFMEAIQASGDISMIGQFGVG 123 Query: 133 FYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQTE 191 FYSAYLVA+ VVVI+K+NDDEQY WES+AGGSFTV D E +GRGTK+ILHLKEDQ E Sbjct: 124 FYSAYLVADHVVVISKNNDDEQYVWESAAGGSFTVTKDETNEKLGRGTKIILHLKEDQLE 183 Query: 192 YLEERRVKEVVKKHSQFIGYPITLYLEK 219 YLEE+R+K++VKKHS+FI +PI LY E+ Sbjct: 184 YLEEKRIKDLVKKHSEFISFPIKLYCER 211 >3Q5K-A nrPDB Length = 231 Score = 314 bits (805), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 150/212 (70%), Positives = 176/212 (83%) Query: 12 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL 71 ETFAFQAEI QLMSLIINTFYSNKEIFLRELISNASDA DKIRY+SLTDPS L L Sbjct: 20 TETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKIRYQSLTDPSVLGESPRL 79 Query: 72 KIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGV 131 I ++P+ + +TLT+ D GIGMTKADL+NNLGTIA+SGTKAFMEAL+AG D+SMIGQFGV Sbjct: 80 CIRVVPDKENKTLTVEDNGIGMTKADLVNNLGTIARSGTKAFMEALEAGGDMSMIGQFGV 139 Query: 132 GFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTE 191 GFYSAYLVA++V V +K+N DE Y WESSAGG+FT+ + + RGT++ LHLKEDQ E Sbjct: 140 GFYSAYLVADRVTVTSKNNSDESYVWESSAGGTFTITSTPESDMKRGTRITLHLKEDQME 199 Query: 192 YLEERRVKEVVKKHSQFIGYPITLYLEKEREK 223 YLE RR+KE++KKHS+FIGY I L +EK EK Sbjct: 200 YLEPRRLKELIKKHSEFIGYDIELMVEKTTEK 231 >6CJJ-A nrPDB Length = 230 Score = 310 bits (794), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 153/212 (72%), Positives = 177/212 (83%), Gaps = 1/212 (0%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ET F AEI+QLMSLIINT YSNKEIFLRELISNASDALDKIRY++L+DPS+L+S EL Sbjct: 19 ETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELF 78 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVG 132 I IIP ++ L + D+GIGMTKADL+NNLGTIAKSGTK+FMEAL AGAD+SMIGQFGVG Sbjct: 79 IRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVG 138 Query: 133 FYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQTE 191 FYS +LVA+ V VI+KHNDDEQY WES+AGG FTV D E +GRGT + L LKEDQ E Sbjct: 139 FYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLE 198 Query: 192 YLEERRVKEVVKKHSQFIGYPITLYLEKEREK 223 YLEE+R+KEVVKKHS+F+ YPI L + KE EK Sbjct: 199 YLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEK 230 >1BGQ-A nrPDB Length = 225 Score = 308 bits (790), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 151/211 (71%), Positives = 178/211 (84%), Gaps = 1/211 (0%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ETF FQAEI QLMSLIINT YSNKEIFLRELISNASDALDKIRY+SL+DP +L++ +L Sbjct: 15 ETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLF 74 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVG 132 I I P P+++ L + D+GIGMTKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGVG Sbjct: 75 IRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVG 134 Query: 133 FYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQTE 191 FYS +LVA++V VI+K NDDEQY WES+AGGSFTV D E IGRGT + L LK+DQ E Sbjct: 135 FYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLE 194 Query: 192 YLEERRVKEVVKKHSQFIGYPITLYLEKERE 222 YLEE+R+KEV+K+HS+F+ YPI L + KE E Sbjct: 195 YLEEKRIKEVIKRHSEFVAYPIQLVVTKEVE 225 >3OMU-A nrPDB Length = 231 Score = 308 bits (788), Expect = 7e-84, Method: Compositional matrix adjust. Identities = 146/212 (68%), Positives = 179/212 (84%) Query: 12 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL 71 ETFAFQAEI QLMSLIINTFYSNKEIFLRELISN+SDA DKIRY+SLT+ S L L Sbjct: 20 TETFAFQAEINQLMSLIINTFYSNKEIFLRELISNSSDACDKIRYQSLTNQSVLGDEPHL 79 Query: 72 KIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGV 131 +I +IP+ +TLT+ D+GIGMTKADL+NNLGTIA+SGTK+FMEAL+AG D+SMIGQFGV Sbjct: 80 RIRVIPDRVNKTLTVEDSGIGMTKADLVNNLGTIARSGTKSFMEALEAGGDMSMIGQFGV 139 Query: 132 GFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTE 191 GFYSAYLVA++V V++K+N+D+ Y WESSAGG+FTV + + RGT+++LHLKEDQ E Sbjct: 140 GFYSAYLVADRVTVVSKNNEDDAYTWESSAGGTFTVTSTPDCDLKRGTRIVLHLKEDQQE 199 Query: 192 YLEERRVKEVVKKHSQFIGYPITLYLEKEREK 223 YLEERR+K+++KKHS+FIGY I L +E EK Sbjct: 200 YLEERRLKDLIKKHSEFIGYDIELMVENTTEK 231 >2AKP-A nrPDB Length = 186 Score = 269 bits (687), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 130/185 (70%), Positives = 157/185 (84%), Gaps = 1/185 (0%) Query: 34 SNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGM 93 SNKEIFLRELISNASDALDKIRY+SL+DP +L++ +L I I P P+++ L + D+GIGM Sbjct: 1 SNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGM 60 Query: 94 TKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDE 153 TKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGVGFYS +LVA++V VI+K NDDE Sbjct: 61 TKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDE 120 Query: 154 QYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYP 212 QY WES+AGGSFTV D E IGRGT + L LK+DQ EYLEE+R+KEV+K+HS+F+ YP Sbjct: 121 QYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYP 180 Query: 213 ITLYL 217 I L + Sbjct: 181 IQLVV 185 >3PEH-A nrPDB Length = 281 Score = 253 bits (647), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 132/267 (49%), Positives = 183/267 (68%), Gaps = 13/267 (4%) Query: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69 E +E+ +Q E+ +LM +I+N+ Y+ KE+FLRELISNA+DAL+KIR+ SL+D S L K Sbjct: 21 ESMESHQYQTEVTRLMDIIVNSLYTQKEVFLRELISNAADALEKIRFLSLSDESVLGEEK 80 Query: 70 ELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEAL-QAGADISMIGQ 128 +L+I I N ++ L++ DTGIGMTK DLINNLGTIAKSGT F+EA+ ++G D+S+IGQ Sbjct: 81 KLEIRISANKEKNILSITDTGIGMTKVDLINNLGTIAKSGTSNFLEAISKSGGDMSLIGQ 140 Query: 129 FGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKE 187 FGVGFYSA+LVA+KV+V TK+NDDEQY WES+A FT+ D G + RGT++ LHLKE Sbjct: 141 FGVGFYSAFLVADKVIVYTKNNDDEQYIWESTADAKFTIYKDPRGATLKRGTRISLHLKE 200 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEK 247 D T L ++++ +++ K+SQFI +PI L E +E+ D A KD Sbjct: 201 DATNLLNDKKLMDLISKYSQFIQFPIYLLHENVYTEEVLADIA-----------KDMVND 249 Query: 248 PKIEDVGSDEEDDSGKDKKKKTKKIKE 274 P + V +E DD K + KK+K+ Sbjct: 250 PNYDSVKVEETDDPNKKTRTVEKKVKK 276 >2GQ0-A nrPDB Length = 303 Score = 236 bits (601), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 119/264 (45%), Positives = 177/264 (67%), Gaps = 8/264 (3%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 + +WTRN +IT EEY EFYK + +D+ D L H VEG+ E+ +LL+IP +AP+D++ Sbjct: 2 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 61 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 N+ K+ +KLYV+RVFIMD ++ +P YL F+RG++DS DLPLN+SRE+LQ S + + + Sbjct: 62 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 120 Query: 405 RKNIVKKCLELFSELA-EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRY---HTS 460 R + K+ L++ +LA +D E Y+ F++ F LK G ED N+ +++LLR+ HT Sbjct: 121 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 180 Query: 461 QSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEY 520 S + SL +YVSRMKE Q+ IYYIT +S +S +E +RK+G EV+ +++ IDE+ Sbjct: 181 SSA-QTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEW 239 Query: 521 CVQQLKEFDGKSLVSVTK--EGLE 542 + L EFDGK SV+K E LE Sbjct: 240 MMNYLTEFDGKPFQSVSKVDESLE 263 >6D28-A nrPDB Length = 273 Score = 227 bits (578), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 119/220 (54%), Positives = 157/220 (71%), Gaps = 7/220 (3%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 H E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + L Sbjct: 3 HMLREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENAL 62 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGA 121 +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 63 AGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQ 122 Query: 122 DIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGT 179 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GRGT Sbjct: 123 STSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDS-NEFSVIADPRGNTLGRGT 181 Query: 180 KVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEK 219 + L LKE+ ++YLE +K +VKK+SQFI +PI ++ K Sbjct: 182 TITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSK 221 >1YT0-A nrPDB Length = 236 Score = 225 bits (574), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 119/220 (54%), Positives = 157/220 (71%), Gaps = 7/220 (3%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 H E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + L Sbjct: 3 HMLREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENAL 62 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGA 121 +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 63 AGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQ 122 Query: 122 DIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGT 179 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GRGT Sbjct: 123 STSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDS-NEFSVIADPRGNTLGRGT 181 Query: 180 KVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEK 219 + L LKE+ ++YLE +K +VKK+SQFI +PI ++ K Sbjct: 182 TITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSK 221 >1Y6Z-A nrPDB Length = 263 Score = 212 bits (540), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 105/257 (40%), Positives = 166/257 (64%), Gaps = 5/257 (1%) Query: 287 PIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFEN 346 PIW ++ +T+ +Y FYK+ ++D LA HF+VEGQ+ F ++L+IP P++L +N Sbjct: 5 PIWKQDEKSLTENDYYSFYKNTFKAYDDPLAYVHFNVEGQISFNSILYIPGSLPWELSKN 64 Query: 347 K--KKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 ++ I+LYV+RVFI D E IP +L F+RG+VDSE+LPLN+ RE+LQ+SK+L +I Sbjct: 65 MFDEESRGIRLYVKRVFINDKFSESIPRWLTFLRGIVDSENLPLNVGREILQKSKMLSII 124 Query: 405 RKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 463 K IV K + + L E + + KF F K LK+G+ ED N+ ++ L+ +++ SG Sbjct: 125 NKRIVLKSISMMKGLKETGGDKWTKFLNTFGKYLKIGVVEDKENQEEIASLVEFYSINSG 184 Query: 464 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 523 D+ T L Y+ MKE QK IYYI+GE+K+ NS +E+++ ++V++ EPIDE+C+ Sbjct: 185 DKKTDLDSYIENMKEDQKCIYYISGENKKTAQNSPSLEKLKALNYDVLFSLEPIDEFCLS 244 Query: 524 QL--KEFDGKSLVSVTK 538 L ++ G ++ V K Sbjct: 245 SLTVNKYKGYEVLDVNK 261 >2IOR-A nrPDB Length = 235 Score = 191 bits (486), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 97/206 (47%), Positives = 146/206 (70%), Gaps = 7/206 (3%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL+ Sbjct: 25 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 84 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFG 130 + + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 85 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 144 Query: 131 VGFYSAYLVAEKVVVITKHNDDE---QYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187 VGFYSA++VA+KV V T+ ++ WES+ G +TV E RGT++ LHL+E Sbjct: 145 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLRE 202 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPI 213 + E+L++ RV+ ++ K+S I P+ Sbjct: 203 GEDEFLDDWRVRSIISKYSDHIALPV 228 >3IED-A nrPDB Length = 272 Score = 186 bits (471), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 102/250 (40%), Positives = 157/250 (62%), Gaps = 44/250 (17%) Query: 12 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRY----ESLTDPSKLDS 67 VE + F+AE+ ++M +I+N+ Y++K++FLRELISNASDA DK R L +++ + Sbjct: 24 VEKYNFKAEVNKVMDIIVNSLYTDKDVFLRELISNASDACDKKRIILENNKLIKDAEVVT 83 Query: 68 GKELKIDI--------------------------------IPNPQERTLTLVDTGIGMTK 95 +E+K + P+ +++TLT+ D GIGM K Sbjct: 84 NEEIKNETEKEKTENVNESTDKKENVEEEKNDIKKLIIKIKPDKEKKTLTITDNGIGMDK 143 Query: 96 ADLINNLGTIAKSGTKAFMEALQAG-ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQ 154 ++LINNLGTIA+SGT F++ ++ G AD ++IGQFGVGFYS++LV+ +V V TK +D+ Sbjct: 144 SELINNLGTIAQSGTAKFLKQIEEGKADSNLIGQFGVGFYSSFLVSNRVEVYTKK-EDQI 202 Query: 155 YAWESSAGGSFTVR------ADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQF 208 Y W S GSF+V ++ + G GTK+ILHLKE+ EYLE+ ++KE++KK+S+F Sbjct: 203 YRWSSDLKGSFSVNEIKKYDQEYDDIKGSGTKIILHLKEECDEYLEDYKLKELIKKYSEF 262 Query: 209 IGYPITLYLE 218 I +PI ++ E Sbjct: 263 IKFPIEIWSE 272 >5TTH-B nrPDB Length = 672 Score = 184 bits (468), Expect = 8e-47, Method: Compositional matrix adjust. Identities = 112/427 (26%), Positives = 231/427 (54%), Gaps = 25/427 (5%) Query: 276 YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 335 +++ LN + +W P DI++ ++ EFY+ + ++ H+ + L R++ ++ Sbjct: 235 FLNGRRLNTLQALWMMEPKDISEWQHEEFYRYVAQAYDKPRYTLHYRADAPLNIRSIFYV 294 Query: 336 PRRAP--FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISRE 393 P P FD+ +++ +++ LY R++ I +++P++L F+RGVVDSED+PLN+S E Sbjct: 295 PEMKPSMFDV--SREMGSSVALYSRKILIQTKATDILPKWLRFLRGVVDSEDIPLNLSAE 352 Query: 394 MLQQSKILKVIRKNIVKKCLE-LFSELAEDKENYKKFYEAFSKNLKLGI--HEDSTNRRR 450 +LQ+S +++ +R + ++ + L + +D E Y +F+E + ++ GI + + + Sbjct: 353 LLQESALIRKLRDVLQQRVIRFLLDQSKKDPEKYARFFEDYGLFMREGIVTTGEQSVKED 412 Query: 451 LSELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFE 509 +++LLR+ +S + TSL EY SRMK ++IYY+ ++ +S + E ++++ E Sbjct: 413 IAKLLRFESSALPAGQQTSLMEYSSRMKAGTRNIYYLCAPNRHLAEHSPYFEAMKQKDME 472 Query: 510 VVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKA--------KFE 561 V++ E DE + L+EFD K L+S ++ D +++K ++SK + E Sbjct: 473 VLFCFEQFDELTLLHLREFDRKKLISAET---DIVVDHYKEEKFQDSKPASERLSSEQAE 529 Query: 562 NLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMM 621 +L M+ L ++V + ++ RL + P I G ++ Q L +S + Sbjct: 530 DLLAWMRNALVQRVTNIKVTPRLDTHPAMITVLEMG---AARHFLRTQQLARSSEERAQI 586 Query: 622 AKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIY 681 + LEIN H +++ L A D N + + L+ +++ A++++G + EDP+ +R+ Sbjct: 587 LQPTLEINTGHDLIKKLH--ALKDSNPELAQLLLEQIYDNAMIAAGLN-EDPRPMISRLN 643 Query: 682 RMIKLGL 688 +++ L Sbjct: 644 QLLTRAL 650 Score = 182 bits (463), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 98/203 (48%), Positives = 138/203 (67%), Gaps = 9/203 (4%) Query: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDII 76 FQAE +L+ ++ + YS KE+F+RELISN SDAL+K+R+ +T D+ ++I + Sbjct: 39 FQAETKKLLDIVARSLYSEKEVFIRELISNGSDALEKLRHRMITAGG--DTAP-MEIHLQ 95 Query: 77 PNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQ--AGADISMIGQFGVGFY 134 + + T T+ DTG+GM K DL++NLGTIA+SG+KAF++ALQ A A S+IGQFGVGFY Sbjct: 96 TDSVKGTFTIQDTGVGMNKEDLVSNLGTIARSGSKAFLDALQNQAEASSSIIGQFGVGFY 155 Query: 135 SAYLVAEKVVVITKH--NDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEY 192 SA++VA+KV V ++ D Y W S G F V G + +GTK++LHLK+D E+ Sbjct: 156 SAFMVADKVEVYSQSAEADAPGYKWSSDGSGVFEVAEASG--VRQGTKIVLHLKDDCKEF 213 Query: 193 LEERRVKEVVKKHSQFIGYPITL 215 E RVKEVV K+S F+ +PI L Sbjct: 214 SSEDRVKEVVTKYSNFVSFPIFL 236 >5F5R-A nrPDB Length = 238 Score = 184 bits (466), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 97/209 (46%), Positives = 143/209 (68%), Gaps = 11/209 (5%) Query: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDII 76 FQAE +L+ ++ + YS KE+F+RELISNASDAL+K+R++ ++D L E++I + Sbjct: 34 FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQAL---PEMEIHLQ 90 Query: 77 PNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS--MIGQFGVGFY 134 N ++ T+T+ DTGIGMT+ +L++NLGTIA+SG+KAF++ALQ A+ S +IGQFGVGFY Sbjct: 91 TNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFY 150 Query: 135 SAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEY 192 SA++VA++V V ++ Y W S G F + G + GTK+I+HLK D E+ Sbjct: 151 SAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASG--VRTGTKIIIHLKSDCKEF 208 Query: 193 LEERRVKEVVKKHSQFIGYPITLYLEKER 221 E RV++VV K+S F+ +P LYL R Sbjct: 209 SSEARVRDVVTKYSNFVSFP--LYLNGRR 235 >4Z1F-A nrPDB Length = 502 Score = 183 bits (465), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 97/209 (46%), Positives = 143/209 (68%), Gaps = 11/209 (5%) Query: 17 FQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDII 76 FQAE +L+ ++ + YS KE+F+RELISNASDAL+K+R++ ++D L E++I + Sbjct: 31 FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQAL---PEMEIHLQ 87 Query: 77 PNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS--MIGQFGVGFY 134 N ++ T+T+ DTGIGMT+ +L++NLGTIA+SG+KAF++ALQ A+ S +IGQFGVGFY Sbjct: 88 TNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFY 147 Query: 135 SAYLVAEKVVVITKHNDDEQ--YAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEY 192 SA++VA++V V ++ Y W S G F + G + GTK+I+HLK D E+ Sbjct: 148 SAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASG--VRTGTKIIIHLKSDCKEF 205 Query: 193 LEERRVKEVVKKHSQFIGYPITLYLEKER 221 E RV++VV K+S F+ +P LYL R Sbjct: 206 SSEARVRDVVTKYSNFVSFP--LYLNGRR 232 Score = 165 bits (417), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 87/268 (32%), Positives = 162/268 (60%), Gaps = 10/268 (3%) Query: 276 YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 335 Y++ +N + IW +P D+ + ++ EFY+ + + H+ + L R++ ++ Sbjct: 227 YLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYV 286 Query: 336 PRRAP--FDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISRE 393 P P FD+ +++ +++ LY R+V I +++P++L FIRGVVDSED+PLN+SRE Sbjct: 287 PDMKPSMFDV--SRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRE 344 Query: 394 MLQQSKILKVIRKNIVKKCLELFSELA-EDKENYKKFYEAFSKNLKLGIHEDSTN--RRR 450 +LQ+S +++ +R + ++ ++ F + + +D E Y KF+E + ++ GI + + Sbjct: 345 LLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKED 404 Query: 451 LSELLRYHTSQ--SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGF 508 +++LLRY +S SG ++TSLSEY SRM+ ++IYY+ ++ +S + E ++K+ Sbjct: 405 IAKLLRYESSALPSG-QLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDT 463 Query: 509 EVVYMTEPIDEYCVQQLKEFDGKSLVSV 536 EV++ E DE + L+EFD K L+SV Sbjct: 464 EVLFCFEQFDELTLLHLREFDKKKLISV 491 >1SF8-A nrPDB Length = 126 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/119 (27%), Positives = 58/119 (48%), Gaps = 12/119 (10%) Query: 567 MKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHL 626 +K +L ++V+ V +++RL +P + T + M ++ A + K Sbjct: 17 VKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEV------KYIF 70 Query: 627 EINPDHPIVETLRQKAEADKNDKA-VKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMI 684 E+NPDH +V K AD D+A + V LL + ALL+ +LEDP R+ +++ Sbjct: 71 ELNPDHVLV-----KRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLL 124 >1FOK-A nrPDB Length = 576 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 54 IRYESLTDPSKLDSGKELKIDIIPN--PQERTLTLVDTGIGMTKADLINNLGTIAKSGTK 111 + Y D S ++ KE+ I+ I + P R LTL++ G +TK DL NLG +SG Sbjct: 133 LAYSKSADGSAIE--KEILIEAISSYPPAIRILTLLEDGQHLTKFDLGKNLGFSGESGFT 190 Query: 112 AFMEAL 117 + E + Sbjct: 191 SLPEGI 196 >2DDU-A nrPDB Length = 387 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 12/77 (15%) Query: 447 NRRRLSELLRYHTSQSGD--EMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVR 504 N R LSE Y+T GD E T ++ + R + K+ + ES Q + V Sbjct: 132 NSRELSEPTVYYT---GDFEEWTRITIAIPRSLASSKTRFRWIQESSSQ-------KNVP 181 Query: 505 KRGFEVVYMTEPIDEYC 521 G + VY++EP YC Sbjct: 182 PFGLDGVYISEPCPSYC 198 >5DBX-A nrPDB Length = 328 Score = 30.4 bits (67), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 23/36 (63%) Query: 421 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLR 456 EDKE KK+ ++F K L L + +D + R +ELL+ Sbjct: 248 EDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 283 >3DAK-A nrPDB Length = 290 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 23/37 (62%) Query: 421 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRY 457 +DKE KK+ ++F K + L + +D R +ELLR+ Sbjct: 247 QDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRH 283 >4GI8-A nrPDB Length = 557 Score = 30.0 bits (66), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/55 (23%), Positives = 28/55 (50%) Query: 613 DNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSG 667 D++ G+ K L++NP++ + R+ + ++L+ + ET LS+G Sbjct: 425 DSANAGFTTGKPWLKVNPNYTEINAAREIGDPKSVYSFYRNLISIRHETPALSTG 479 >1NAR-A nrPDB Length = 290 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Query: 242 KDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEY 301 KDD+ + + E + S K KK ++D + N+ KP+ T + + Sbjct: 153 KDDDLNINVVSIAPSENNSSHYQKLYNAKKDYINWVDYQFSNQQKPV-------STDDAF 205 Query: 302 GEFYKSLTNDWEDHLAVKHFSVE 324 E +KSL D+ H + FS + Sbjct: 206 VEIFKSLEKDYHPHKVLPGFSTD 228 >4GCZ-A nrPDB Length = 385 Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 11/80 (13%) Query: 19 AEIAQLMSLIINTFYSNKEIFL----RELI-SNASDALDKIRYESLTDPSKLDSGKELKI 73 A+ Q+ +++N F + E REL+ +N A D I E D+G + Sbjct: 264 ADRVQIQQVLVNLFRNALEAMAQSQRRELVVTNTPAADDMIEVEVS------DTGSGFQD 317 Query: 74 DIIPNPQERTLTLVDTGIGM 93 D+IPN + T DTG+G+ Sbjct: 318 DVIPNLFQTFFTTKDTGMGV 337 >2QU8-A nrPDB Length = 228 Score = 29.3 bits (64), Expect = 6.5, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Query: 29 INTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVD 88 IN FYS K +F + I + +DK +SL+ +KL + L D + NP + + Sbjct: 130 INLFYSIKSVFSNKSIVIGFNKIDKCNMDSLSIDNKLLIKQIL--DNVKNPIKFSSFSTL 187 Query: 89 TGIGMTKADL 98 TG+G+ +A + Sbjct: 188 TGVGVEQAKI 197 >6IGX-B nrPDB Length = 839 Score = 29.3 bits (64), Expect = 7.0, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 11/74 (14%) Query: 525 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVE-------- 576 ++ F K + ++ EG E+ D+E++ K E A +N+ KL+ + LD +V Sbjct: 593 IEPFKTKKIKTLHCEGTEINSDDEQESKEVEETATAKNVLKLLSDFLDSEVSELRTGAAE 652 Query: 577 ---KVTISNRLVSS 587 K+ S LVSS Sbjct: 653 GLAKLMFSGLLVSS 666 >1A41-A nrPDB Length = 234 Score = 28.9 bits (63), Expect = 8.9, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 23/34 (67%), Gaps = 1/34 (2%) Query: 604 RIMKAQALRDNSTMGYMMAK-KHLEINPDHPIVE 636 R K + L++N T+G + K KH+EI+PD +++ Sbjct: 50 RFGKMKYLKENETVGLLTLKNKHIEISPDEIVIK 83 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FWK-A nrPDB 1055 0.0 2CG9-A nrPDB 896 0.0 2O1V-A nrPDB 859 0.0 2IOQ-A nrPDB 744 0.0 1Y4U-A nrPDB 681 0.0 2O1W-A nrPDB 675 0.0 3Q6N-A nrPDB 630 0.0 3HJC-A nrPDB 579 e-165 2O1T-A nrPDB 559 e-159 2CGE-A nrPDB 554 e-158 5TTH-B nrPDB 476 e-134 1HK7-A nrPDB 413 e-115 3PRY-A nrPDB 403 e-112 1USV-A nrPDB 394 e-110 5UCI-A nrPDB 384 e-106 6B9A-B nrPDB 378 e-105 5J6L-A nrPDB 368 e-102 2GQ0-A nrPDB 364 e-101 4X9L-A nrPDB 364 e-101 5NYI-A nrPDB 360 e-100 2XCM-A nrPDB 359 3e-99 3Q5K-A nrPDB 358 5e-99 3OMU-A nrPDB 355 4e-98 3K60-A nrPDB 347 8e-96 4GQT-A nrPDB 347 1e-95 4XDM-A nrPDB 342 2e-94 4Z1F-A nrPDB 342 3e-94 1BGQ-A nrPDB 342 4e-94 6CJJ-A nrPDB 341 6e-94 3PEH-A nrPDB 331 8e-91 1Y6Z-A nrPDB 328 4e-90 1YT0-A nrPDB 312 4e-85 6D28-A nrPDB 311 8e-85 2AKP-A nrPDB 302 3e-82 2IOR-A nrPDB 296 2e-80 5F5R-A nrPDB 276 3e-74 3IED-A nrPDB 240 1e-63 1SF8-A nrPDB 126 4e-29 Sequences not found previously or not previously below threshold: 4P7A-A nrPDB 40 0.005 5Y63-A nrPDB 34 0.26 2HK1-A nrPDB 34 0.36 2PX0-A nrPDB 32 0.69 5Y5Z-N nrPDB 32 0.85 5XMU-A nrPDB 32 0.86 6IGC-A nrPDB 32 0.88 3D36-A nrPDB 32 1.1 2WMI-B nrPDB 32 1.1 1DZL-A nrPDB 32 1.3 6IGE-A nrPDB 32 1.4 5O9X-A nrPDB 31 2.1 1Q78-A nrPDB 31 2.1 2R5J-A nrPDB 31 2.4 1VYT-A nrPDB 30 2.6 1VYV-A nrPDB 30 2.7 4KPA-A nrPDB 30 3.2 3V7C-A nrPDB 30 4.2 3FHO-A nrPDB 30 5.0 6NMI-A nrPDB 29 6.3 5OF4-A nrPDB 29 7.6 5IY9-V nrPDB 29 8.9 3L1R-A nrPDB 29 9.9 CONVERGED! >5FWK-A nrPDB Length = 727 Score = 1055 bits (2729), Expect = 0.0, Method: Composition-based stats. Identities = 724/724 (100%), Positives = 724/724 (100%) Query: 1 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 60 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT Sbjct: 4 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 63 Query: 61 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 120 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG Sbjct: 64 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 123 Query: 121 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 180 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK Sbjct: 124 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 183 Query: 181 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 240 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE Sbjct: 184 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 243 Query: 241 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 300 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE Sbjct: 244 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE 303 Query: 301 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV 360 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV Sbjct: 304 YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV 363 Query: 361 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA 420 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA Sbjct: 364 FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA 423 Query: 421 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ 480 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ Sbjct: 424 EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ 483 Query: 481 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG 540 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG Sbjct: 484 KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG 543 Query: 541 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA 600 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA Sbjct: 544 LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA 603 Query: 601 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE 660 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE Sbjct: 604 NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE 663 Query: 661 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM 720 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM Sbjct: 664 TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM 723 Query: 721 EEVD 724 EEVD Sbjct: 724 EEVD 727 >2CG9-A nrPDB Length = 677 Score = 896 bits (2314), Expect = 0.0, Method: Composition-based stats. Identities = 426/680 (62%), Positives = 544/680 (80%), Gaps = 7/680 (1%) Query: 12 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL 71 ETF FQAEI QLMSLIINT YSNKEIFLRELISNASDALDKIRY+SL+DP +L++ +L Sbjct: 3 SETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDL 62 Query: 72 KIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGV 131 I I P P+++ L + D+GIGMTKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGV Sbjct: 63 FIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGV 122 Query: 132 GFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQT 190 GFYS +LVA++V VI+K NDDEQY WES+AGGSFTV D E IGRGT + L LK+DQ Sbjct: 123 GFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQL 182 Query: 191 EYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKI 250 EYLEE+R+KEV+K+HS+F+ YPI L + KE EKE+ E E++ EK++E+K DE+ K Sbjct: 183 EYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKP 242 Query: 251 EDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTN 310 + DEE++ KK ++++E EELNKTKP+WTRNP DITQEEY FYKS++N Sbjct: 243 KLEEVDEEEEKKPKTKKVKEEVQE----IEELNKTKPLWTRNPSDITQEEYNAFYKSISN 298 Query: 311 DWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELI 370 DWED L VKHFSVEGQLEFRA+LFIP+RAPFDLFE+KKKKNNIKLYVRRVFI D ++LI Sbjct: 299 DWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLI 358 Query: 371 PEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFY 430 PE+L+F++GVVDSEDLPLN+SREMLQQ+KI+KVIRKNIVKK +E F+E+AED E ++KFY Sbjct: 359 PEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFY 418 Query: 431 EAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGES 490 AFSKN+KLG+HED+ NR L++LLRY++++S DE+TSL++YV+RM E QK+IYYITGES Sbjct: 419 SAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGES 478 Query: 491 KEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550 + V S F++ ++ + FEV+++T+PIDEY QLKEF+GK+LV +TK+ EL E +EEK Sbjct: 479 LKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKD-FELEETDEEK 537 Query: 551 KKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQA 610 + E+ ++E L K +KEIL +VEKV +S +L+ +P I T +GW+ANMERIMKAQA Sbjct: 538 AEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQA 597 Query: 611 LRDNSTMGYMMAKKHLEINPDHPIVETLRQKA-EADKNDKAVKDLVVLLFETALLSSGFS 669 LRD+S YM +KK EI+P PI++ L+++ E DK VKDL LL+ETALL+SGFS Sbjct: 598 LRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFS 657 Query: 670 LEDPQTHSNRIYRMIKLGLG 689 L++P + ++RI R+I LGL Sbjct: 658 LDEPTSFASRINRLISLGLN 677 >2O1V-A nrPDB Length = 666 Score = 859 bits (2219), Expect = 0.0, Method: Composition-based stats. Identities = 322/700 (46%), Positives = 448/700 (64%), Gaps = 61/700 (8%) Query: 5 VHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSK 64 V G E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + Sbjct: 15 VPRGSHMSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENA 74 Query: 65 LDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAG 120 L +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 75 LAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDG 134 Query: 121 ADIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGT 179 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + + G +GRGT Sbjct: 135 QSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGT 194 Query: 180 KVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEE 239 + L LKE+ ++YLE +K +VKK+SQFI +PI ++ Sbjct: 195 TITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVW----------------------- 231 Query: 240 EDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQE 299 S + GK D E +N KPIW R ++ + Sbjct: 232 ---------------SSKTGGGGK-----------TVWDWELMNDIKPIWQRPSKEVEDD 265 Query: 300 EYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFE--NKKKKNNIKLYV 357 EY FYKS + + +D +A HF+ EG++ F+++LF+P AP LF+ KK + IKLYV Sbjct: 266 EYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYV 325 Query: 358 RRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFS 417 RRVFI D +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK +V+K L++ Sbjct: 326 RRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIK 385 Query: 418 ELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMK 477 ++A++K N F++ F N+KLG+ ED +NR RL++LLR+ +S ++TSL +YV RMK Sbjct: 386 KIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDITSLDQYVERMK 444 Query: 478 ETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVT 537 E Q IY++ G S+++ +S FVER+ K+G+EV+Y+TEP+DEYC+Q L EFDGK +V Sbjct: 445 EKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVA 504 Query: 538 KEGLELPEDEEEKKKMEESKAKFENLCKLMKE-ILDKKVEKVTISNRLVSSPCCIVTSTY 596 KEG++ E E+ K+ E + +FE L MK+ L K+EK +S RL SPC +V S Y Sbjct: 505 KEGVKFDESEKTKESREAIEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQY 564 Query: 597 GWTANMERIMKAQAL---RDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKD 653 GW+ NMERIMKAQA +D ST Y KK EINP HP+++ + ++ + D++DK V D Sbjct: 565 GWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKEDEDDKTVSD 624 Query: 654 LVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDED 693 L V+LFETA L SG+ L D + + +RI RM++L L ID D Sbjct: 625 LAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPD 664 >2IOQ-A nrPDB Length = 624 Score = 744 bits (1920), Expect = 0.0, Method: Composition-based stats. Identities = 258/683 (37%), Positives = 396/683 (57%), Gaps = 76/683 (11%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL+ Sbjct: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFG 130 + + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 Query: 131 VGFYSAYLVAEKVVVITKHNDDE---QYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187 VGFYSA++VA+KV V T+ ++ WES+ G +TV E RGT++ LHL+E Sbjct: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLRE 182 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEK 247 + E+L++ + + + SD A + EK EE Sbjct: 183 GEDEFLDD--------------------WRVRSIISKYSDHIALPVEIEKREE------- 215 Query: 248 PKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKS 307 K E I E++NK + +WTRN +IT EEY EFYK Sbjct: 216 -----------------------KDGETVISWEKINKAQALWTRNKSEITDEEYKEFYKH 252 Query: 308 LTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCD 367 + +D+ D L H VEG+ E+ +LL+IP +AP+D++ N+ K+ +KLYV+RVFIMD + Sbjct: 253 IAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW-NRDHKHGLKLYVQRVFIMDDAE 311 Query: 368 ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA-EDKENY 426 + +P YL F+RG++DS DLPLN+SRE+LQ S + + +R + K+ L++ +LA +D E Y Sbjct: 312 QFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKY 371 Query: 427 KKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQ--SGDEMTSLSEYVSRMKETQKSIY 484 + F++ F LK G ED N+ +++LLR+ ++ S + SL +YVSRMKE Q+ IY Sbjct: 372 QTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIY 431 Query: 485 YITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK--EGLE 542 YIT +S +S +E +RK+G EV+ +++ IDE+ + L EFDGK SV+K E LE Sbjct: 432 YITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLE 491 Query: 543 LPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANM 602 DE ++ E KA +K +L ++V+ V +++RL +P + T + M Sbjct: 492 KLADEVDESAKEAEKA-LTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQM 550 Query: 603 ERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKA-VKDLVVLLFET 661 ++ A + K E+NPDH +V+ AD D+A + V LL + Sbjct: 551 AKLFAAAGQKVPEV------KYIFELNPDHVLVK-----RAADTEDEAKFSEWVELLLDQ 599 Query: 662 ALLSSGFSLEDPQTHSNRIYRMI 684 ALL+ +LEDP R+ +++ Sbjct: 600 ALLAERGTLEDPNLFIRRMNQLL 622 >1Y4U-A nrPDB Length = 559 Score = 681 bits (1757), Expect = 0.0, Method: Composition-based stats. Identities = 236/609 (38%), Positives = 361/609 (59%), Gaps = 64/609 (10%) Query: 13 ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELK 72 ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P + EL+ Sbjct: 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELR 64 Query: 73 IDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--GADISMIGQFG 130 + + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + D +IGQFG Sbjct: 65 VRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFG 124 Query: 131 VGFYSAYLVAEKVVVITKHNDDE---QYAWESSAGGSFTVRADHGEPIGRGTKVILHLKE 187 VGFYSA++VA+KV V T+ ++ WES+ G +TV E RGT++ LHL+E Sbjct: 125 VGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--RGTEITLHLRE 182 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEK 247 + E+L++ + + + SD A + EK EE Sbjct: 183 GEDEFLDD--------------------WRVRSIISKYSDHIALPVEIEKREE------- 215 Query: 248 PKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKS 307 K E I E++NK + +WTRN +IT EEY EFYK Sbjct: 216 -----------------------KDGETVISWEKINKAQALWTRNKSEITDEEYKEFYKH 252 Query: 308 LTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCD 367 + +D+ D L H VEG+ E+ +LL+IP +AP+D++ N+ K+ +KLYV+RVFIMD + Sbjct: 253 IAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW-NRDHKHGLKLYVQRVFIMDDAE 311 Query: 368 ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA-EDKENY 426 + +P YL F+RG++DS DLPLN+SRE+LQ S + + +R + K+ L++ +LA +D E Y Sbjct: 312 QFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKY 371 Query: 427 KKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQ--SGDEMTSLSEYVSRMKETQKSIY 484 + F++ F LK G ED N+ +++LLR+ ++ S + SL +YVSRMKE Q+ IY Sbjct: 372 QTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIY 431 Query: 485 YITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTK--EGLE 542 YIT +S +S +E +RK+G EV+ +++ IDE+ + L EFDGK SV+K E LE Sbjct: 432 YITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLE 491 Query: 543 LPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANM 602 DE ++ E KA +K +L ++V+ V +++RL +P + T + M Sbjct: 492 KLADEVDESAKEAEKA-LTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQM 550 Query: 603 ERIMKAQAL 611 ++ A Sbjct: 551 AKLFAAAGQ 559 >2O1W-A nrPDB Length = 506 Score = 675 bits (1742), Expect = 0.0, Method: Composition-based stats. Identities = 253/543 (46%), Positives = 351/543 (64%), Gaps = 59/543 (10%) Query: 5 VHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSK 64 V G E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + Sbjct: 15 VPRGSHMSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENA 74 Query: 65 LDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAG 120 L +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 75 LAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDG 134 Query: 121 ADIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRG 178 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GRG Sbjct: 135 QSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSN-EFSVIADPRGNTLGRG 193 Query: 179 TKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKE 238 T + L LKE+ ++YLE +K +VKK+SQFI +PI ++ Sbjct: 194 TTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVW---------------------- 231 Query: 239 EEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQ 298 S + GK D E +N KPIW R ++ Sbjct: 232 ----------------SSKTGGGGK-----------TVWDWELMNDIKPIWQRPSKEVED 264 Query: 299 EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFE--NKKKKNNIKLY 356 +EY FYKS + + +D +A HF+ EG++ F+++LF+P AP LF+ KK + IKLY Sbjct: 265 DEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLY 324 Query: 357 VRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELF 416 VRRVFI D +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK +V+K L++ Sbjct: 325 VRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMI 384 Query: 417 SELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRM 476 ++A++K N F++ F N+KLG+ ED +NR RL++LLR+ +S ++TSL +YV RM Sbjct: 385 KKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDITSLDQYVERM 443 Query: 477 KETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSV 536 KE Q IY++ G S+++ +S FVER+ K+G+EV+Y+TEP+DEYC+Q L EFDGK +V Sbjct: 444 KEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNV 503 Query: 537 TKE 539 KE Sbjct: 504 AKE 506 >3Q6N-A nrPDB Length = 448 Score = 630 bits (1624), Expect = 0.0, Method: Composition-based stats. Identities = 382/440 (86%), Positives = 417/440 (94%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 TKPIWTRNPDDIT EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF+PRRAPFDLF Sbjct: 3 TKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLF 62 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 EN+KKKNNIKLYVRRVFIMD+C+ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI Sbjct: 63 ENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 122 Query: 405 RKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGD 464 RKN+VKKCLELF+ELAEDKENYKKFYE FSKN+KLGIHEDS NR++LSELLRY+TS SGD Sbjct: 123 RKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGD 182 Query: 465 EMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQ 524 EM SL +Y +RMKE QK IYYITGE+K+QVANSAFVER+RK G EV+YM EPIDEYCVQQ Sbjct: 183 EMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQ 242 Query: 525 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRL 584 LKEF+GK+LVSVTKEGLELPEDEEEKKK EE K KFENLCK+MK+IL+KKVEKV +SNRL Sbjct: 243 LKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRL 302 Query: 585 VSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEA 644 V+SPCCIVTSTYGWTANMERIMKAQALRDNSTMGYM AKKHLEINPDH I+ETLRQKAEA Sbjct: 303 VTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEA 362 Query: 645 DKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAV 704 DKNDK+VKDLV+LL+ETALLSSGFSLEDPQTH+NRIYRMIKLGLGIDED+ A++ +AAV Sbjct: 363 DKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAV 422 Query: 705 PDEIPPLEGDEDASRMEEVD 724 +E+PPLEGD+D SRMEEVD Sbjct: 423 TEEMPPLEGDDDTSRMEEVD 442 >3HJC-A nrPDB Length = 444 Score = 579 bits (1492), Expect = e-165, Method: Composition-based stats. Identities = 262/406 (64%), Positives = 343/406 (84%) Query: 286 KPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFE 345 KP+WTR+P D+T+EEY FYK+++NDWED A KHFSVEGQLEFR+++F+P+RAPFD+FE Sbjct: 20 KPLWTRDPKDVTKEEYAAFYKAISNDWEDPAATKHFSVEGQLEFRSIMFVPKRAPFDMFE 79 Query: 346 NKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIR 405 KK+NNIKLYVRRVFIMD+C++L P++L F++GVVDSEDLPLNISRE LQQ+KILKVIR Sbjct: 80 PNKKRNNIKLYVRRVFIMDNCEDLCPDWLGFVKGVVDSEDLPLNISRENLQQNKILKVIR 139 Query: 406 KNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDE 465 KNIVKKCLE+F E+AE+KE+YK+FYE F KN+KLGIHED+ NR++L ELLR+++++SG+E Sbjct: 140 KNIVKKCLEMFDEVAENKEDYKQFYEQFGKNIKLGIHEDTANRKKLMELLRFYSTESGEE 199 Query: 466 MTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQL 525 MT+L +YV+RMK QKSIYYITG+SK+++ S F+E+ R+RG EV++MTEPIDEY +QQ+ Sbjct: 200 MTTLKDYVTRMKAGQKSIYYITGDSKKKLETSPFIEQARRRGLEVLFMTEPIDEYVMQQV 259 Query: 526 KEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLV 585 K+F+ K +TKEG+ E EEEK++ EE KA E LCK MKE+L KVEKV +S RL Sbjct: 260 KDFEDKKFACLTKEGVHFEESEEEKQQREEEKAACEKLCKTMKEVLGDKVEKVIVSERLS 319 Query: 586 SSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEAD 645 +SPC +VTS +GW+A+ME+IM+ QALRD+S YMM+KK +E+NP HPI++ LR++ AD Sbjct: 320 TSPCILVTSEFGWSAHMEQIMRNQALRDSSMAQYMMSKKTMELNPRHPIIKELRRRVGAD 379 Query: 646 KNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGID 691 +NDKAVKDLV LLF+T+LL+SGF LEDP ++ RI RMIKLGL +D Sbjct: 380 ENDKAVKDLVFLLFDTSLLTSGFQLEDPTGYAERINRMIKLGLSLD 425 >2O1T-A nrPDB Length = 450 Score = 559 bits (1441), Expect = e-159, Method: Composition-based stats. Identities = 203/421 (48%), Positives = 291/421 (69%), Gaps = 7/421 (1%) Query: 279 QEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRR 338 +N KPIW R ++ +EY FYKS + + +D +A HF+ EG++ F+++LF+P Sbjct: 18 GSHMNDIKPIWQRPSKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTS 77 Query: 339 APFDLFE--NKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQ 396 AP LF+ KK + IKLYVRRVFI D +++P+YLNF++GVVDS+DLPLN+SRE LQ Sbjct: 78 APRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQ 137 Query: 397 QSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLR 456 Q K+LKVIRK +V+K L++ ++A++K N F++ F N+KLG+ ED +NR RL++LLR Sbjct: 138 QHKLLKVIRKKLVRKTLDMIKKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLR 196 Query: 457 YHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEP 516 + +S ++TSL +YV RMKE Q IY++ G S+++ +S FVER+ K+G+EV+Y+TEP Sbjct: 197 FQSSHHPSDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEP 256 Query: 517 IDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKE-ILDKKV 575 +DEYC+Q L EFDGK +V KEG++ E E+ K+ E + +FE L MK+ L K+ Sbjct: 257 VDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAIEKEFEPLLNWMKDKALKDKI 316 Query: 576 EKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQAL---RDNSTMGYMMAKKHLEINPDH 632 EK +S RL SPC +V S YGW+ NMERIMKAQA +D ST Y KK EINP H Sbjct: 317 EKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRH 376 Query: 633 PIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDE 692 P+++ + ++ + D++DK V DL V+LFETA L SG+ L D + + +RI RM++L L ID Sbjct: 377 PLIKDMLRRVKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDP 436 Query: 693 D 693 D Sbjct: 437 D 437 >2CGE-A nrPDB Length = 405 Score = 554 bits (1427), Expect = e-158, Method: Composition-based stats. Identities = 253/406 (62%), Positives = 330/406 (81%), Gaps = 2/406 (0%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 TKP+WTRNP DITQEEY FYKS++NDWED L VKHFSVEGQLEFRA+LFIP+RAPFDLF Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 E+KKKKNNIKLYVRRVFI D ++LIPE+L+F++GVVDSEDLPLN+SREMLQQ+KI+KVI Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 405 RKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGD 464 RKNIVKK +E F+E+AED E ++KFY AFSKN+KLG+HED+ NR L++LLRY++++S D Sbjct: 121 RKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVD 180 Query: 465 EMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQ 524 E+TSL++YV+RM E QK+IYYITGES + V S F++ ++ + FEV+++T+PIDEY Q Sbjct: 181 ELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQ 240 Query: 525 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRL 584 LKEF+GK+LV +TK+ EL E +EEK + E+ ++E L K +KEIL +VEKV +S +L Sbjct: 241 LKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKL 299 Query: 585 VSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKA-E 643 + +P I T +GW+ANMERIMKAQALRD+S YM +KK EI+P PI++ L+++ E Sbjct: 300 LDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDE 359 Query: 644 ADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLG 689 DK VKDL LL+ETALL+SGFSL++P + ++RI R+I LGL Sbjct: 360 GGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLN 405 >5TTH-B nrPDB Length = 672 Score = 476 bits (1225), Expect = e-134, Method: Composition-based stats. Identities = 110/425 (25%), Positives = 228/425 (53%), Gaps = 21/425 (4%) Query: 276 YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 335 +++ LN + +W P DI++ ++ EFY+ + ++ H+ + L R++ ++ Sbjct: 235 FLNGRRLNTLQALWMMEPKDISEWQHEEFYRYVAQAYDKPRYTLHYRADAPLNIRSIFYV 294 Query: 336 PRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREML 395 P P +++ +++ LY R++ I +++P++L F+RGVVDSED+PLN+S E+L Sbjct: 295 PEMKPSMFDVSREMGSSVALYSRKILIQTKATDILPKWLRFLRGVVDSEDIPLNLSAELL 354 Query: 396 QQSKILKVIRKNIVKKCLE-LFSELAEDKENYKKFYEAFSKNLKLGIH--EDSTNRRRLS 452 Q+S +++ +R + ++ + L + +D E Y +F+E + ++ GI + + + ++ Sbjct: 355 QESALIRKLRDVLQQRVIRFLLDQSKKDPEKYARFFEDYGLFMREGIVTTGEQSVKEDIA 414 Query: 453 ELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVV 511 +LLR+ +S + TSL EY SRMK ++IYY+ ++ +S + E ++++ EV+ Sbjct: 415 KLLRFESSALPAGQQTSLMEYSSRMKAGTRNIYYLCAPNRHLAEHSPYFEAMKQKDMEVL 474 Query: 512 YMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKA--------KFENL 563 + E DE + L+EFD K L+S + + D +++K ++SK + E+L Sbjct: 475 FCFEQFDELTLLHLREFDRKKLISAETD---IVVDHYKEEKFQDSKPASERLSSEQAEDL 531 Query: 564 CKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAK 623 M+ L ++V + ++ RL + P I G ++ Q L +S + + Sbjct: 532 LAWMRNALVQRVTNIKVTPRLDTHPAMITVLEMG---AARHFLRTQQLARSSEERAQILQ 588 Query: 624 KHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRM 683 LEIN H +++ L A D N + + L+ +++ A++++G + EDP+ +R+ ++ Sbjct: 589 PTLEINTGHDLIKKLH--ALKDSNPELAQLLLEQIYDNAMIAAGLN-EDPRPMISRLNQL 645 Query: 684 IKLGL 688 + L Sbjct: 646 LTRAL 650 >1HK7-A nrPDB Length = 288 Score = 413 bits (1061), Expect = e-115, Method: Composition-based stats. Identities = 190/289 (65%), Positives = 244/289 (84%), Gaps = 1/289 (0%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 TKP+WTRNP DITQEEY FYKS++NDWED L VKHFSVEGQLEFRA+LFIP+RAPFDLF Sbjct: 1 TKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLF 60 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 E+KKKKNNIKLYVRRVFI D ++LIPE+L+F++GVVDSEDLPLN+SREMLQQ+KI+KVI Sbjct: 61 ESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVI 120 Query: 405 RKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGD 464 RKNIVKK +E F+E+AED E ++KFY AFSKN+KLG+HED+ NR L++LLRY++++S D Sbjct: 121 RKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVD 180 Query: 465 EMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQ 524 E+TSL++YV+RM E QK+IYYITGES + V S F++ ++ + FEV+++T+PIDEY Q Sbjct: 181 ELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQ 240 Query: 525 LKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDK 573 LKEF+GK+LV +TK+ EL E +EEK + E+ ++E L K +KEIL Sbjct: 241 LKEFEGKTLVDITKD-FELEETDEEKAEREKEIKEYEPLTKALKEILGD 288 >3PRY-A nrPDB Length = 268 Score = 403 bits (1035), Expect = e-112, Method: Composition-based stats. Identities = 261/263 (99%), Positives = 262/263 (99%) Query: 284 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 343 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL Sbjct: 2 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 61 Query: 344 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 403 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV Sbjct: 62 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 121 Query: 404 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 463 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG Sbjct: 122 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 181 Query: 464 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 523 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ Sbjct: 182 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 241 Query: 524 QLKEFDGKSLVSVTKEGLELPED 546 QLKEFDGKSLVSVTKEGLEL E+ Sbjct: 242 QLKEFDGKSLVSVTKEGLELAEN 264 >1USV-A nrPDB Length = 260 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 177/256 (69%), Positives = 225/256 (87%) Query: 284 KTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDL 343 KTKP+WTRNP DITQEEY FYKS++NDWED L VKHFSVEGQLEFRA+LFIP+RAPFDL Sbjct: 2 KTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDL 61 Query: 344 FENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKV 403 FE+KKKKNNIKLYVRRVFI D ++LIPE+L+F++GVVDSEDLPLN+SREMLQQ+KI+KV Sbjct: 62 FESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKV 121 Query: 404 IRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 463 IRKNIVKK +E F+E+AED E ++KFY AFSKN+KLG+HED+ NR L++LLRY++++S Sbjct: 122 IRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSV 181 Query: 464 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 523 DE+TSL++YV+RM E QK+IYYITGES + V S F++ ++ + FEV+++T+PIDEY Sbjct: 182 DELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFT 241 Query: 524 QLKEFDGKSLVSVTKE 539 QLKEF+GK+LV +TK+ Sbjct: 242 QLKEFEGKTLVDITKD 257 >5UCI-A nrPDB Length = 220 Score = 384 bits (985), Expect = e-106, Method: Composition-based stats. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 1 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 60 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT Sbjct: 3 MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT 62 Query: 61 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 120 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG Sbjct: 63 DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG 122 Query: 121 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 180 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK Sbjct: 123 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK 182 Query: 181 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE 218 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE Sbjct: 183 VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE 220 >6B9A-B nrPDB Length = 256 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 210/236 (88%), Positives = 222/236 (94%), Gaps = 5/236 (2%) Query: 1 MPEEV-----HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIR 55 MPEE EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIR Sbjct: 21 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 80 Query: 56 YESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFME 115 YESLTDPSKLDSGKEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAKSGTKAFME Sbjct: 81 YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 140 Query: 116 ALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPI 175 ALQAGADISMIGQFGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+ Sbjct: 141 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 200 Query: 176 GRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231 GRGTKVILHLKEDQTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAE Sbjct: 201 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAE 256 >5J6L-A nrPDB Length = 228 Score = 368 bits (945), Expect = e-102, Method: Composition-based stats. Identities = 205/226 (90%), Positives = 217/226 (96%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRYESLTDPSKL Sbjct: 3 PMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKL 62 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISM 125 DSGKEL I++IPN Q+RTLT+VDTGIGMTKADLINN GTIAKSGTKAFMEALQAGADISM Sbjct: 63 DSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNAGTIAKSGTKAFMEALQAGADISM 122 Query: 126 IGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHL 185 IGQFGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+GRGTKVILHL Sbjct: 123 IGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHL 182 Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231 KEDQTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAE Sbjct: 183 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAE 228 >2GQ0-A nrPDB Length = 303 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 118/267 (44%), Positives = 178/267 (66%), Gaps = 6/267 (2%) Query: 285 TKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLF 344 + +WTRN +IT EEY EFYK + +D+ D L H VEG+ E+ +LL+IP +AP+D++ Sbjct: 2 AQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMW 61 Query: 345 ENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 N+ K+ +KLYV+RVFIMD ++ +P YL F+RG++DS DLPLN+SRE+LQ S + + + Sbjct: 62 -NRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNL 120 Query: 405 RKNIVKKCLELFSELA-EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQ-- 461 R + K+ L++ +LA +D E Y+ F++ F LK G ED N+ +++LLR+ ++ Sbjct: 121 RNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTD 180 Query: 462 SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYC 521 S + SL +YVSRMKE Q+ IYYIT +S +S +E +RK+G EV+ +++ IDE+ Sbjct: 181 SSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWM 240 Query: 522 VQQLKEFDGKSLVSVTK--EGLELPED 546 + L EFDGK SV+K E LE D Sbjct: 241 MNYLTEFDGKPFQSVSKVDESLEKLAD 267 >4X9L-A nrPDB Length = 250 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 160/215 (74%), Positives = 186/215 (86%), Gaps = 1/215 (0%) Query: 9 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSG 68 E ETFAFQAEI QL+SLIINTFYSNKEIFLRELISN+SDALDKIR+ESLTD SKLD+ Sbjct: 36 ASETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQ 95 Query: 69 KELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQ 128 EL I I+P+ TL+++D+G+GMTK+DL+NNLGTIA+SGTK FMEAL AGAD+SMIGQ Sbjct: 96 PELFIHIVPDKASNTLSIIDSGVGMTKSDLVNNLGTIARSGTKEFMEALAAGADVSMIGQ 155 Query: 129 FGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKE 187 FGVGFYSAYLVAE+VVV TKHNDDEQY WES AGGSFTV D GE +GRGTK+ L+LK+ Sbjct: 156 FGVGFYSAYLVAERVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKITLYLKD 215 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 222 DQ EYLEERR+K++VKKHS+FI YPI+L+ EK E Sbjct: 216 DQLEYLEERRLKDLVKKHSEFISYPISLWTEKTTE 250 >5NYI-A nrPDB Length = 229 Score = 360 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 190/226 (84%), Positives = 217/226 (96%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 EEEVETFAFQAEIAQLM+LIINTFY+NKEIFLRELI+N +DALDKIRYE+LTDP+KL Sbjct: 4 PMEEEEVETFAFQAEIAQLMTLIINTFYTNKEIFLRELITNTTDALDKIRYETLTDPTKL 63 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISM 125 D+GKEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAK+GTKAFMEALQAGADI+M Sbjct: 64 DTGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKTGTKAFMEALQAGADITM 123 Query: 126 IGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHL 185 IGQFGVGFY+AYLVAEKV VITKHNDDEQYAWE++AGG+FTVR D GEP+GRGTKVILHL Sbjct: 124 IGQFGVGFYTAYLVAEKVTVITKHNDDEQYAWETTAGGTFTVRTDTGEPMGRGTKVILHL 183 Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAE 231 KEDQTEYLEERR+KE+VKKH+QFIGYPITL++E+ER+KE++DDEAE Sbjct: 184 KEDQTEYLEERRIKEIVKKHTQFIGYPITLFVEEERDKEVTDDEAE 229 >2XCM-A nrPDB Length = 214 Score = 359 bits (921), Expect = 3e-99, Method: Composition-based stats. Identities = 162/212 (76%), Positives = 185/212 (87%), Gaps = 1/212 (0%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 H E ETFAFQAEI QL+SLIINTFYSNKEIFLRELISN+SDALDKIR+ESLTD SKL Sbjct: 2 HAAATETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKL 61 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISM 125 D+ EL I IIP+ TLT+VD+GIGMTK+DL+NNLGTIA+SGTK FMEAL AGAD+SM Sbjct: 62 DAQPELFIHIIPDKATSTLTIVDSGIGMTKSDLVNNLGTIARSGTKEFMEALAAGADVSM 121 Query: 126 IGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILH 184 IGQFGVGFYSAYLVAE+VVV TKHNDDEQY WES AGGSFTV D GE +GRGTK++L+ Sbjct: 122 IGQFGVGFYSAYLVAERVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKMVLY 181 Query: 185 LKEDQTEYLEERRVKEVVKKHSQFIGYPITLY 216 LK+DQ EYLEERR+K++VKKHS+FI YPI+L+ Sbjct: 182 LKDDQMEYLEERRIKDLVKKHSEFISYPISLW 213 >3Q5K-A nrPDB Length = 231 Score = 358 bits (919), Expect = 5e-99, Method: Composition-based stats. Identities = 150/213 (70%), Positives = 176/213 (82%) Query: 11 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKE 70 ETFAFQAEI QLMSLIINTFYSNKEIFLRELISNASDA DKIRY+SLTDPS L Sbjct: 19 MTETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKIRYQSLTDPSVLGESPR 78 Query: 71 LKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG 130 L I ++P+ + +TLT+ D GIGMTKADL+NNLGTIA+SGTKAFMEAL+AG D+SMIGQFG Sbjct: 79 LCIRVVPDKENKTLTVEDNGIGMTKADLVNNLGTIARSGTKAFMEALEAGGDMSMIGQFG 138 Query: 131 VGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQT 190 VGFYSAYLVA++V V +K+N DE Y WESSAGG+FT+ + + RGT++ LHLKEDQ Sbjct: 139 VGFYSAYLVADRVTVTSKNNSDESYVWESSAGGTFTITSTPESDMKRGTRITLHLKEDQM 198 Query: 191 EYLEERRVKEVVKKHSQFIGYPITLYLEKEREK 223 EYLE RR+KE++KKHS+FIGY I L +EK EK Sbjct: 199 EYLEPRRLKELIKKHSEFIGYDIELMVEKTTEK 231 >3OMU-A nrPDB Length = 231 Score = 355 bits (910), Expect = 4e-98, Method: Composition-based stats. Identities = 146/213 (68%), Positives = 179/213 (84%) Query: 11 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKE 70 ETFAFQAEI QLMSLIINTFYSNKEIFLRELISN+SDA DKIRY+SLT+ S L Sbjct: 19 MTETFAFQAEINQLMSLIINTFYSNKEIFLRELISNSSDACDKIRYQSLTNQSVLGDEPH 78 Query: 71 LKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG 130 L+I +IP+ +TLT+ D+GIGMTKADL+NNLGTIA+SGTK+FMEAL+AG D+SMIGQFG Sbjct: 79 LRIRVIPDRVNKTLTVEDSGIGMTKADLVNNLGTIARSGTKSFMEALEAGGDMSMIGQFG 138 Query: 131 VGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQT 190 VGFYSAYLVA++V V++K+N+D+ Y WESSAGG+FTV + + RGT+++LHLKEDQ Sbjct: 139 VGFYSAYLVADRVTVVSKNNEDDAYTWESSAGGTFTVTSTPDCDLKRGTRIVLHLKEDQQ 198 Query: 191 EYLEERRVKEVVKKHSQFIGYPITLYLEKEREK 223 EYLEERR+K+++KKHS+FIGY I L +E EK Sbjct: 199 EYLEERRLKDLIKKHSEFIGYDIELMVENTTEK 231 >3K60-A nrPDB Length = 223 Score = 347 bits (891), Expect = 8e-96, Method: Composition-based stats. Identities = 157/210 (74%), Positives = 178/210 (84%), Gaps = 1/210 (0%) Query: 11 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKE 70 ETFAF A+I QLMSLIINTFYSNKEIFLRELISNASDALDKIRYES+TD KL + E Sbjct: 2 STETFAFNADIRQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESITDTQKLSAEPE 61 Query: 71 LKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG 130 I IIP+ TLT+ D+GIGMTK DLINNLGTIA+SGTKAFMEA+QA DISMIGQFG Sbjct: 62 FFIRIIPDKTNNTLTIEDSGIGMTKNDLINNLGTIARSGTKAFMEAIQASGDISMIGQFG 121 Query: 131 VGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQ 189 VGFYSAYLVA+ VVVI+K+NDDEQY WES+AGGSFTV D E +GRGTK+ILHLKEDQ Sbjct: 122 VGFYSAYLVADHVVVISKNNDDEQYVWESAAGGSFTVTKDETNEKLGRGTKIILHLKEDQ 181 Query: 190 TEYLEERRVKEVVKKHSQFIGYPITLYLEK 219 EYLEE+R+K++VKKHS+FI +PI LY E+ Sbjct: 182 LEYLEEKRIKDLVKKHSEFISFPIKLYCER 211 >4GQT-A nrPDB Length = 227 Score = 347 bits (889), Expect = 1e-95, Method: Composition-based stats. Identities = 161/209 (77%), Positives = 188/209 (89%) Query: 7 HGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLD 66 E ETFAFQAEIAQLMSLIINTFYSNKEI+LRELISNASDALDKIRY++LT+PS+LD Sbjct: 3 AMSENAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELD 62 Query: 67 SGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMI 126 +GKEL I I PN +E+TLT++DTGIGMTKADL+NNLGTIAKSGTKAFMEALQAGADISMI Sbjct: 63 TGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMI 122 Query: 127 GQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLK 186 GQFGVGFYSA+LVA+KVVV +K+NDD+ Y WESSAGGSF VR + + RGTK+++H+K Sbjct: 123 GQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIK 182 Query: 187 EDQTEYLEERRVKEVVKKHSQFIGYPITL 215 EDQ ++LEER++KE+VKKHSQFIGYPI L Sbjct: 183 EDQIDFLEERKIKEIVKKHSQFIGYPIKL 211 >4XDM-A nrPDB Length = 259 Score = 342 bits (878), Expect = 2e-94, Method: Composition-based stats. Identities = 154/217 (70%), Positives = 184/217 (84%), Gaps = 1/217 (0%) Query: 7 HGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLD 66 E +VE F FQAEI QLMSLIINTFYSNKE+FLRELISNASDALDKIRY+SLTD S L+ Sbjct: 37 MAESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLE 96 Query: 67 SGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG-ADISM 125 S EL+I IIP+ +TLTL+D+GIGMTK D++ NLGTIA+SGTK FME LQ+G ADISM Sbjct: 97 SKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISM 156 Query: 126 IGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHL 185 IGQFGVGFYSAYLVA+ V+V +K+NDDEQY WESSAGG FT+ DH EP+GRGTK++LH+ Sbjct: 157 IGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHM 216 Query: 186 KEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKERE 222 KEDQ +YL+E ++K +VKKHS+FI YPI+L KE+E Sbjct: 217 KEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEKE 253 >4Z1F-A nrPDB Length = 502 Score = 342 bits (878), Expect = 3e-94, Method: Composition-based stats. Identities = 84/279 (30%), Positives = 161/279 (57%), Gaps = 7/279 (2%) Query: 276 YIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFI 335 Y++ +N + IW +P D+ + ++ EFY+ + + H+ + L R++ ++ Sbjct: 227 YLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYV 286 Query: 336 PRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREML 395 P P +++ +++ LY R+V I +++P++L FIRGVVDSED+PLN+SRE+L Sbjct: 287 PDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELL 346 Query: 396 QQSKILKVIRKNIVKKCLELF-SELAEDKENYKKFYEAFSKNLKLGIHEDSTN--RRRLS 452 Q+S +++ +R + ++ ++ F + +D E Y KF+E + ++ GI + + ++ Sbjct: 347 QESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIA 406 Query: 453 ELLRYHTSQ-SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVV 511 +LLRY +S ++TSLSEY SRM+ ++IYY+ ++ +S + E ++K+ EV+ Sbjct: 407 KLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVL 466 Query: 512 YMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEK 550 + E DE + L+EFD K L+SV + + D ++ Sbjct: 467 FCFEQFDELTLLHLREFDKKKLISVETD---IVVDHYKE 502 >1BGQ-A nrPDB Length = 225 Score = 342 bits (876), Expect = 4e-94, Method: Composition-based stats. Identities = 151/212 (71%), Positives = 178/212 (83%), Gaps = 1/212 (0%) Query: 12 VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKEL 71 ETF FQAEI QLMSLIINT YSNKEIFLRELISNASDALDKIRY+SL+DP +L++ +L Sbjct: 14 SETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDL 73 Query: 72 KIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGV 131 I I P P+++ L + D+GIGMTKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGV Sbjct: 74 FIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGV 133 Query: 132 GFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQT 190 GFYS +LVA++V VI+K NDDEQY WES+AGGSFTV D E IGRGT + L LK+DQ Sbjct: 134 GFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQL 193 Query: 191 EYLEERRVKEVVKKHSQFIGYPITLYLEKERE 222 EYLEE+R+KEV+K+HS+F+ YPI L + KE E Sbjct: 194 EYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVE 225 >6CJJ-A nrPDB Length = 230 Score = 341 bits (874), Expect = 6e-94, Method: Composition-based stats. Identities = 153/214 (71%), Positives = 178/214 (83%), Gaps = 1/214 (0%) Query: 11 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKE 70 + ET F AEI+QLMSLIINT YSNKEIFLRELISNASDALDKIRY++L+DPS+L+S E Sbjct: 17 QGETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPE 76 Query: 71 LKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFG 130 L I IIP ++ L + D+GIGMTKADL+NNLGTIAKSGTK+FMEAL AGAD+SMIGQFG Sbjct: 77 LFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFG 136 Query: 131 VGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQ 189 VGFYS +LVA+ V VI+KHNDDEQY WES+AGG FTV D E +GRGT + L LKEDQ Sbjct: 137 VGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQ 196 Query: 190 TEYLEERRVKEVVKKHSQFIGYPITLYLEKEREK 223 EYLEE+R+KEVVKKHS+F+ YPI L + KE EK Sbjct: 197 LEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEK 230 >3PEH-A nrPDB Length = 281 Score = 331 bits (848), Expect = 8e-91, Method: Composition-based stats. Identities = 133/276 (48%), Positives = 185/276 (67%), Gaps = 17/276 (6%) Query: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69 E +E+ +Q E+ +LM +I+N+ Y+ KE+FLRELISNA+DAL+KIR+ SL+D S L K Sbjct: 21 ESMESHQYQTEVTRLMDIIVNSLYTQKEVFLRELISNAADALEKIRFLSLSDESVLGEEK 80 Query: 70 ELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEAL-QAGADISMIGQ 128 +L+I I N ++ L++ DTGIGMTK DLINNLGTIAKSGT F+EA+ ++G D+S+IGQ Sbjct: 81 KLEIRISANKEKNILSITDTGIGMTKVDLINNLGTIAKSGTSNFLEAISKSGGDMSLIGQ 140 Query: 129 FGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKE 187 FGVGFYSA+LVA+KV+V TK+NDDEQY WES+A FT+ D G + RGT++ LHLKE Sbjct: 141 FGVGFYSAFLVADKVIVYTKNNDDEQYIWESTADAKFTIYKDPRGATLKRGTRISLHLKE 200 Query: 188 DQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEK 247 D T L ++++ +++ K+SQFI +PI L E +E+ D A KD Sbjct: 201 DATNLLNDKKLMDLISKYSQFIQFPIYLLHENVYTEEVLADIA-----------KDMVND 249 Query: 248 PKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELN 283 P + V +E DD K + KK+K+ +N Sbjct: 250 PNYDSVKVEETDDPNKKTRTVEKKVKK----WTLMN 281 >1Y6Z-A nrPDB Length = 263 Score = 328 bits (842), Expect = 4e-90, Method: Composition-based stats. Identities = 105/257 (40%), Positives = 166/257 (64%), Gaps = 5/257 (1%) Query: 287 PIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFEN 346 PIW ++ +T+ +Y FYK+ ++D LA HF+VEGQ+ F ++L+IP P++L +N Sbjct: 5 PIWKQDEKSLTENDYYSFYKNTFKAYDDPLAYVHFNVEGQISFNSILYIPGSLPWELSKN 64 Query: 347 K--KKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVI 404 ++ I+LYV+RVFI D E IP +L F+RG+VDSE+LPLN+ RE+LQ+SK+L +I Sbjct: 65 MFDEESRGIRLYVKRVFINDKFSESIPRWLTFLRGIVDSENLPLNVGREILQKSKMLSII 124 Query: 405 RKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSG 463 K IV K + + L E + + KF F K LK+G+ ED N+ ++ L+ +++ SG Sbjct: 125 NKRIVLKSISMMKGLKETGGDKWTKFLNTFGKYLKIGVVEDKENQEEIASLVEFYSINSG 184 Query: 464 DEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQ 523 D+ T L Y+ MKE QK IYYI+GE+K+ NS +E+++ ++V++ EPIDE+C+ Sbjct: 185 DKKTDLDSYIENMKEDQKCIYYISGENKKTAQNSPSLEKLKALNYDVLFSLEPIDEFCLS 244 Query: 524 QL--KEFDGKSLVSVTK 538 L ++ G ++ V K Sbjct: 245 SLTVNKYKGYEVLDVNK 261 >1YT0-A nrPDB Length = 236 Score = 312 bits (799), Expect = 4e-85, Method: Composition-based stats. Identities = 119/221 (53%), Positives = 157/221 (71%), Gaps = 7/221 (3%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 H E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + L Sbjct: 3 HMLREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENAL 62 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGA 121 +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 63 AGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQ 122 Query: 122 DIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGT 179 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GRGT Sbjct: 123 STSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSN-EFSVIADPRGNTLGRGT 181 Query: 180 KVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKE 220 + L LKE+ ++YLE +K +VKK+SQFI +PI ++ K Sbjct: 182 TITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKT 222 >6D28-A nrPDB Length = 273 Score = 311 bits (796), Expect = 8e-85, Method: Composition-based stats. Identities = 135/284 (47%), Positives = 183/284 (64%), Gaps = 19/284 (6%) Query: 6 HHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKL 65 H E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD + L Sbjct: 3 HMLREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENAL 62 Query: 66 DSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGA 121 +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G Sbjct: 63 AGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQ 122 Query: 122 DIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGT 179 S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GRGT Sbjct: 123 STSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSN-EFSVIADPRGNTLGRGT 181 Query: 180 KVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEE 239 + L LKE+ ++YLE +K +VKK+SQFI +PI ++ K E +E E K EKE+ Sbjct: 182 TITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKED 241 Query: 240 EDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELN 283 D + + + E+ KTKK+++ D E +N Sbjct: 242 SDDEAAVEEEEEEKK------------PKTKKVEKTVWDWELMN 273 >2AKP-A nrPDB Length = 186 Score = 302 bits (774), Expect = 3e-82, Method: Composition-based stats. Identities = 130/186 (69%), Positives = 157/186 (84%), Gaps = 1/186 (0%) Query: 34 SNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGM 93 SNKEIFLRELISNASDALDKIRY+SL+DP +L++ +L I I P P+++ L + D+GIGM Sbjct: 1 SNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGM 60 Query: 94 TKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDE 153 TKA+LINNLGTIAKSGTKAFMEAL AGAD+SMIGQFGVGFYS +LVA++V VI+K NDDE Sbjct: 61 TKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDE 120 Query: 154 QYAWESSAGGSFTVRADH-GEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYP 212 QY WES+AGGSFTV D E IGRGT + L LK+DQ EYLEE+R+KEV+K+HS+F+ YP Sbjct: 121 QYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYP 180 Query: 213 ITLYLE 218 I L + Sbjct: 181 IQLVVT 186 >2IOR-A nrPDB Length = 235 Score = 296 bits (758), Expect = 2e-80, Method: Composition-based stats. Identities = 99/218 (45%), Positives = 149/218 (68%), Gaps = 9/218 (4%) Query: 5 VHHGEEE--VETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDP 62 V G ET FQ+E+ QL+ L+I++ YSNKEIFLRELISNASDA DK+R+ +L++P Sbjct: 15 VPRGSHMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNP 74 Query: 63 SKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQA--G 120 + EL++ + + +RTLT+ D G+GMT+ ++I++LGTIAKSGTK+F+E+L + Sbjct: 75 DLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQA 134 Query: 121 ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDE---QYAWESSAGGSFTVRADHGEPIGR 177 D +IGQFGVGFYSA++VA+KV V T+ ++ WES+ G +TV E R Sbjct: 135 KDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKED--R 192 Query: 178 GTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITL 215 GT++ LHL+E + E+L++ RV+ ++ K+S I P+ + Sbjct: 193 GTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEI 230 >5F5R-A nrPDB Length = 238 Score = 276 bits (706), Expect = 3e-74, Method: Composition-based stats. Identities = 94/209 (44%), Positives = 141/209 (67%), Gaps = 9/209 (4%) Query: 11 EVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKE 70 FQAE +L+ ++ + YS KE+F+RELISNASDAL+K+R++ ++D L E Sbjct: 28 STSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQAL---PE 84 Query: 71 LKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS--MIGQ 128 ++I + N ++ T+T+ DTGIGMT+ +L++NLGTIA+SG+KAF++ALQ A+ S +IGQ Sbjct: 85 MEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQ 144 Query: 129 FGVGFYSAYLVAEKVVVITKHN--DDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLK 186 FGVGFYSA++VA++V V ++ Y W S G F + G + GTK+I+HLK Sbjct: 145 FGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASG--VRTGTKIIIHLK 202 Query: 187 EDQTEYLEERRVKEVVKKHSQFIGYPITL 215 D E+ E RV++VV K+S F+ +P+ L Sbjct: 203 SDCKEFSSEARVRDVVTKYSNFVSFPLYL 231 >3IED-A nrPDB Length = 272 Score = 240 bits (613), Expect = 1e-63, Method: Composition-based stats. Identities = 103/259 (39%), Positives = 160/259 (61%), Gaps = 44/259 (16%) Query: 3 EEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRY----ES 58 E ++ VE + F+AE+ ++M +I+N+ Y++K++FLRELISNASDA DK R Sbjct: 15 ENLYFQGSPVEKYNFKAEVNKVMDIIVNSLYTDKDVFLRELISNASDACDKKRIILENNK 74 Query: 59 LTDPSKLDSGKELKIDI--------------------------------IPNPQERTLTL 86 L +++ + +E+K + P+ +++TLT+ Sbjct: 75 LIKDAEVVTNEEIKNETEKEKTENVNESTDKKENVEEEKNDIKKLIIKIKPDKEKKTLTI 134 Query: 87 VDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG-ADISMIGQFGVGFYSAYLVAEKVVV 145 D GIGM K++LINNLGTIA+SGT F++ ++ G AD ++IGQFGVGFYS++LV+ +V V Sbjct: 135 TDNGIGMDKSELINNLGTIAQSGTAKFLKQIEEGKADSNLIGQFGVGFYSSFLVSNRVEV 194 Query: 146 ITKHNDDEQYAWESSAGGSFTVRA------DHGEPIGRGTKVILHLKEDQTEYLEERRVK 199 TK +D+ Y W S GSF+V ++ + G GTK+ILHLKE+ EYLE+ ++K Sbjct: 195 YTKK-EDQIYRWSSDLKGSFSVNEIKKYDQEYDDIKGSGTKIILHLKEECDEYLEDYKLK 253 Query: 200 EVVKKHSQFIGYPITLYLE 218 E++KK+S+FI +PI ++ E Sbjct: 254 ELIKKYSEFIKFPIEIWSE 272 >1SF8-A nrPDB Length = 126 Score = 126 bits (316), Expect = 4e-29, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 12/123 (9%) Query: 563 LCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMA 622 +K +L ++V+ V +++RL +P + T + M ++ A + Sbjct: 13 FIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEV------ 66 Query: 623 KKHLEINPDHPIVETLRQKAEADKNDKA-VKDLVVLLFETALLSSGFSLEDPQTHSNRIY 681 K E+NPDH +V+ AD D+A + V LL + ALL+ +LEDP R+ Sbjct: 67 KYIFELNPDHVLVK-----RAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMN 121 Query: 682 RMI 684 +++ Sbjct: 122 QLL 124 >4P7A-A nrPDB Length = 348 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 32/148 (21%), Positives = 56/148 (37%), Gaps = 24/148 (16%) Query: 82 RTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAE 141 + + + D G G+ K D L + + T + +++ + A IS G G S VA Sbjct: 58 KLIQIQDNGTGIRKED----LDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVA- 112 Query: 142 KVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILH------------LKEDQ 189 V + TK D + S + G +GT++ + LK Sbjct: 113 HVTITTKTADGKCAYRASYSDGKLK-APPKPCAGNQGTQITVEDLFYNIATRRKALKNPS 171 Query: 190 TEYLEERRVKEVVKKHSQF---IGYPIT 214 EY ++ EVV ++S I + + Sbjct: 172 EEY---GKILEVVGRYSVHNAGISFSVK 196 >5Y63-A nrPDB Length = 183 Score = 33.9 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 12/70 (17%) Query: 45 SNASDALDKIRYESLTDPS--------KLDSGKELKID----IIPNPQERTLTLVDTGIG 92 ++A++ + KI+Y L DP+ LD + + P ++ + D GIG Sbjct: 94 ADATETIGKIKYPMLADPNGQLARFFGVLDEASGMAYRASFIVSPEGDIKSYEINDMGIG 153 Query: 93 MTKADLINNL 102 +L+ L Sbjct: 154 RNAEELVRKL 163 >2HK1-A nrPDB Length = 309 Score = 33.5 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 27/67 (40%), Gaps = 10/67 (14%) Query: 476 MKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVS 535 MK IYY E + ++E+V K GF+++ E + E+ L + Sbjct: 21 MKHG---IYYSYWEHEWSAKFGPYIEKVAKLGFDII-------EVAAHHINEYSDAELAT 70 Query: 536 VTKEGLE 542 + K + Sbjct: 71 IRKSAKD 77 >2PX0-A nrPDB Length = 296 Score = 32.4 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 37/173 (21%), Positives = 64/173 (36%), Gaps = 12/173 (6%) Query: 387 PLNISREMLQQSKILKVIRKNIVKKCLELFSELAE-DKENYKKFYEAFSKNLKLGIHEDS 445 PL + ++LQ++ I + + N +KK L E +EN + ++ D Sbjct: 41 PLRKAEKLLQETGIKESTKTNTLKKLLRFSVEAGGLTEENVVGKLQEILCDML--PSADK 98 Query: 446 TNRRRLSELLRYHTSQSGDEMTSLSEYVS-RMKETQKSIYYITGESKE--QVANSAFVER 502 S+ + S + T+L++ + M E K I +IT ++ V Sbjct: 99 WQEPIHSKYIVLFGSTGAGKTTTLAKLAAISMLEKHKKIAFITTDTYRIAAVEQLKTYAE 158 Query: 503 VRKRGFEVVYMTEPIDEYCVQQLKE-FDGKSLVSVTKEGLELPEDEEEKKKME 554 + + EV Y E QQ KE F V V G + + + E Sbjct: 159 LLQAPLEVCYTKEEF-----QQAKELFSEYDHVFVDTAGRNFKDPQYIDELKE 206 >5Y5Z-N nrPDB Length = 652 Score = 32.0 bits (71), Expect = 0.85, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 4/84 (4%) Query: 441 IHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSI---YYITGESKEQVANS 497 E S R+ L++L R S T + V+R+K ++ + V Sbjct: 228 PRELSEVRQHLAKLARESASTLQSLWTRAQDEVARLKALEELASGRFGFALLGYVPVKAK 287 Query: 498 AFVERVRKRGFE-VVYMTEPIDEY 520 VE R E VVY EP+DE+ Sbjct: 288 PKVEEALARHKESVVYAFEPVDEH 311 >5XMU-A nrPDB Length = 442 Score = 32.0 bits (71), Expect = 0.86, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 528 FDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCK-LMKEILDKKVEK 577 F+ + L + KE ++ DEE++++ + ENL ++E L +V Sbjct: 2 FNNEPLEQIDKELHDILADEEKRQRETINLIASENLTNGAVRECLGNRVSN 52 >6IGC-A nrPDB Length = 524 Score = 32.0 bits (71), Expect = 0.88, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 17/39 (43%), Gaps = 5/39 (12%) Query: 462 SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFV 500 ++ S EYVSR SIYY G S+ + + Sbjct: 43 PVSKVVSTDEYVSR-----TSIYYYAGSSRLLAVGNPYF 76 >3D36-A nrPDB Length = 244 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 19/36 (52%) Query: 63 SKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADL 98 + +G L++ + + + + DTG+GMTK L Sbjct: 137 EAMPNGGTLQVYVSIDNGRVLIRIADTGVGMTKEQL 172 >2WMI-B nrPDB Length = 606 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 13/105 (12%) Query: 9 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSG 68 E E T+ I+ + + +N F +NK+ L SNA DA + LT + Sbjct: 482 EFEPHTYGIFERISNGLKVNLNNFRTNKD----SLWSNAQDANQAKKLPQLTKKGAIKWI 537 Query: 69 KELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTI-AKSGTKA 112 +E I ++R +V GI + L TI + SGT Sbjct: 538 EEHYIKDTQFGEKRVTKIVLRGI--------DKLPTIHSLSGTNN 574 >1DZL-A nrPDB Length = 505 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 20/50 (40%), Gaps = 5/50 (10%) Query: 462 SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVV 511 ++ S EYV+R +IYY G S+ + + +++ Sbjct: 17 PVSKVVSTDEYVAR-----TNIYYHAGTSRLLAVGHPYFPIKKPNNNKIL 61 >6IGE-A nrPDB Length = 499 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 16/39 (41%), Gaps = 5/39 (12%) Query: 462 SGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFV 500 ++ S EYVSR SIYY G S+ + Sbjct: 17 PVSKVVSTDEYVSR-----TSIYYYAGSSRLLAVGHPYF 50 >5O9X-A nrPDB Length = 549 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 52/147 (35%), Gaps = 1/147 (0%) Query: 142 KVVVITKHNDDEQYAW-ESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKE 200 VV K+ QY + E + G + A + + RG KV L D + +++E Sbjct: 168 HYVVRCKNTLGTQYEYGEPTEQGYYEKLAAAFKRVMRGVKVKGSLTVDCANGVGGPKLRE 227 Query: 201 VVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDD 260 ++K + G I + + + + E + + ++ + ++ S + D Sbjct: 228 LIKYLPEDTGLDIKIVNDDVINPDSLNFECGADYVKTKQRAPPSSKASILDRCASLDGDA 287 Query: 261 SGKDKKKKTKKIKEKYIDQEELNKTKP 287 + + +D + + Sbjct: 288 DRILYYFLDEGNVFRLLDGDRIATLAA 314 >1Q78-A nrPDB Length = 514 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 30/56 (53%), Gaps = 9/56 (16%) Query: 335 IPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNI 390 + PF +FE +++ RR+ I+ + L+ E+ IR + +S++LP ++ Sbjct: 43 VETLKPFGVFEEEEELQ------RRILILGKLNNLVKEW---IREISESKNLPQSV 89 >2R5J-A nrPDB Length = 423 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 19/42 (45%), Gaps = 6/42 (14%) Query: 466 MTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRG 507 + S EYV+R +IYY G S+ + ++K+ Sbjct: 2 VVSTDEYVTR-----TNIYYHAGSSRLLAVGHPYY-AIKKQD 37 >1VYT-A nrPDB Length = 351 Score = 30.5 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 28/193 (14%), Positives = 67/193 (34%), Gaps = 23/193 (11%) Query: 183 LHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDK 242 LH+KE +Y + + +VK+ I + I + E K+E+ Sbjct: 78 LHIKE---KYSNDWWIGRLVKEGGD-IAF-------------IPSPQRLESIRLKQEQKA 120 Query: 243 DDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPD----DITQ 298 P K+ +K E + + +P+ P ++T Sbjct: 121 RRSGNPS-SLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTD 179 Query: 299 EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIP-RRAPFDLFENKKKKNNIKLYV 357 + L + ++ +++ + + L R++L P +R + + ++ + Sbjct: 180 MMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEI 239 Query: 358 RRVFIMDSCDELI 370 R+F + +L+ Sbjct: 240 ERIFELAKSLQLV 252 >1VYV-A nrPDB Length = 359 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 29/186 (15%), Positives = 72/186 (38%), Gaps = 18/186 (9%) Query: 183 LHLKEDQTEYLEERRVKEVVKKHSQ--FIGYPITLYLEKEREKEISDDEAEEEKGEKEEE 240 LH+KE +Y + + +VK+ + FI P+ L E + E+++ Sbjct: 77 LHIKE---KYNNDWWIGRLVKEGCEIGFIPSPLRL--------ENIRIQQEQKRKRFHGG 125 Query: 241 DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPD----DI 296 + ++ S + K+ +K+ + + + +P+ P ++ Sbjct: 126 KSSGNSSSSLGEMVSGTFRATPTTTAKQKQKVTKHIPPYDVVPSMRPVVLVGPSLKGYEV 185 Query: 297 TQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIP-RRAPFDLFENKKKKNNIKL 355 T + L + ++ +++ + + L R++L P +RA + K ++ Sbjct: 186 TDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTKSSLAEVQS 245 Query: 356 YVRRVF 361 + R+F Sbjct: 246 EIERIF 251 >4KPA-A nrPDB Length = 494 Score = 30.1 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 31/79 (39%), Gaps = 10/79 (12%) Query: 640 QKAEADKNDKAVKDLVVLLFETALLS------SGFSLEDPQTHSNRIYRMIKLGLG---- 689 ++ AD++ + +D+ L +T L + F + P + R + + Sbjct: 155 ERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQR 214 Query: 690 IDEDEVAAEEPNAAVPDEI 708 + D+ A +E ++I Sbjct: 215 ANPDDPAYDENKRQFQEDI 233 >3V7C-A nrPDB Length = 329 Score = 29.7 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Query: 177 RGTKVILHLKEDQTEY-LEERRVKEVVKKHSQFIGYPI-TLYLEKEREKEISDDEAEEEK 234 R T + LH K Y ER ++E+ K+++QF+ P + E I + + Sbjct: 227 RATSIQLHDKNKLDRYQFLERLLQEIEKRYNQFLTLPFSEIREEYIAASNIWNRTLLFTE 286 Query: 235 GEKEEEDKDDEEKPKIEDVGSDEEDDSGK 263 +K+ + + + + DE +S + Sbjct: 287 NDKQFKGQAIDLDYDGYLIVRDEAGESHR 315 >3FHO-A nrPDB Length = 508 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 27/97 (27%), Gaps = 2/97 (2%) Query: 215 LYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKE 274 L + I + D+ P+ G+ + Sbjct: 411 LVTTNVIARGIDVSQVNLVVNYDMPLDQAGRPDPQTYLHRIGRTGRFGRVGVSINFVHDK 470 Query: 275 KYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTND 311 K EE+N + + R + ++Y E K + N Sbjct: 471 K--SWEEMNAIQEYFQRPITRVPTDDYEELEKVVKNA 505 >6NMI-A nrPDB Length = 653 Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 52/141 (36%), Gaps = 8/141 (5%) Query: 233 EKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWT-- 290 +GE+ + ++ + PKI + + D+ D + I+ + + + Sbjct: 508 SQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVL 567 Query: 291 RNPDDITQEEYGEFYKSLTNDWEDHLAVK----HFSVEGQLEFRALLFIPRRAPFDLFEN 346 R + EEY F+ SL + +A F V+ F+ + + DL + Sbjct: 568 RAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFS 627 Query: 347 KKKKNNIKLYVRRVFIMDSCD 367 K++ L ++V D Sbjct: 628 TKEEQQQLL--QKVLAATDLD 646 >5OF4-A nrPDB Length = 553 Score = 28.9 bits (63), Expect = 7.6, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 52/141 (36%), Gaps = 8/141 (5%) Query: 233 EKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWT-- 290 +GE+ + ++ + PKI + + D+ D + I+ + + + Sbjct: 356 SQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVL 415 Query: 291 RNPDDITQEEYGEFYKSLTNDWEDHLAVK----HFSVEGQLEFRALLFIPRRAPFDLFEN 346 R + EEY F+ SL + +A F V+ F+ + + DL + Sbjct: 416 RAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFS 475 Query: 347 KKKKNNIKLYVRRVFIMDSCD 367 K++ L ++V D Sbjct: 476 TKEEQQQLL--QKVLAATDLD 494 >5IY9-V nrPDB Length = 782 Score = 28.9 bits (63), Expect = 8.9, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 52/141 (36%), Gaps = 8/141 (5%) Query: 233 EKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWT-- 290 +GE+ + ++ + PKI + + D+ D + I+ + + + Sbjct: 585 SQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVL 644 Query: 291 RNPDDITQEEYGEFYKSLTNDWEDHLAVK----HFSVEGQLEFRALLFIPRRAPFDLFEN 346 R + EEY F+ SL + +A F V+ F+ + + DL + Sbjct: 645 RAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFS 704 Query: 347 KKKKNNIKLYVRRVFIMDSCD 367 K++ L ++V D Sbjct: 705 TKEEQQQLL--QKVLAATDLD 723 >3L1R-A nrPDB Length = 478 Score = 28.5 bits (62), Expect = 9.9, Method: Composition-based stats. Identities = 12/105 (11%), Positives = 34/105 (32%) Query: 208 FIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKK 267 F+ +P + E + + + +E + + V +E+ +++ Sbjct: 302 FLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQS 361 Query: 268 KTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDW 312 + E ++ K + + + FYK ++W Sbjct: 362 DEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNW 406 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.130 0.332 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,580,800 Number of Sequences: 36641 Number of extensions: 1035945 Number of successful extensions: 5281 Number of sequences better than 10.0: 74 Number of HSP's better than 10.0 without gapping: 157 Number of HSP's successfully gapped in prelim test: 119 Number of HSP's that attempted gapping in prelim test: 3522 Number of HSP's gapped (non-prelim): 892 length of query: 724 length of database: 10,336,785 effective HSP length: 104 effective length of query: 620 effective length of database: 6,526,121 effective search space: 4046195020 effective search space used: 4046195020 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.5 bits) S2: 63 (28.9 bits)