BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08203 (231 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1K0W-A nrPDB 479 e-136 4C25-A nrPDB 80 8e-16 2IRP-A nrPDB 56 1e-08 1E4A-P nrPDB 53 1e-07 4XXF-A nrPDB 51 4e-07 1PVT-A nrPDB 39 0.002 2Z7B-A nrPDB 35 0.023 4M6R-A nrPDB 34 0.066 4PIC-A nrPDB 30 0.69 6GCS-A nrPDB 30 0.75 6J5C-A nrPDB 29 2.1 3JRW-A nrPDB 28 2.2 2YL2-A nrPDB 28 2.3 5CWW-B nrPDB 27 5.4 1K8Q-A nrPDB 27 5.5 2Z8S-A nrPDB 27 6.4 >1K0W-A nrPDB Length = 231 Score = 479 bits (1232), Expect = e-136, Method: Compositional matrix adjust. Identities = 227/231 (98%), Positives = 230/231 (99%) Query: 1 MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVS 60 MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYS+MTADDMVVVS Sbjct: 1 MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSIMTADDMVVVS 60 Query: 61 IETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHAD 120 IETGEVVEG KKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHA+ Sbjct: 61 IETGEVVEGAKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHAN 120 Query: 121 YFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNA 180 YFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNA Sbjct: 121 YFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNA 180 Query: 181 EDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ 231 EDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLL+KHYLRKHGAKAYYGQ Sbjct: 181 EDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLNKHYLRKHGAKAYYGQ 231 >4C25-A nrPDB Length = 212 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 66/227 (29%), Positives = 110/227 (48%), Gaps = 35/227 (15%) Query: 4 DLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIET 63 D+K+++++ L + +L T GN+S DRE+ + I PSG+D+ + D+VV+ I Sbjct: 8 DVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDI-N 66 Query: 64 GEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFY 123 G VVEG + PSS+ H + YQ I I+H H+ +AT+ A + +PA+ Y Sbjct: 67 GNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVLACLREPLPAS-----HYMI 121 Query: 124 GTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQ-MPG---VLVHSHGPFAWGKN 179 ++ + G E ++AA+ M G VL+ +HG A +N Sbjct: 122 AVAGKDVRVAEYATYGTKEL-------------AVNAAKAMEGRRAVLLANHGILAGAQN 168 Query: 180 AEDAVHNAIVLEEVAYMG-IFCRQLAPQ------LPDMQQTLLDKHY 219 +A + ++EEV Y I+C LA LPD + L+ + + Sbjct: 169 LLNAFN---IVEEVEYCAKIYC--LAKNFGEPVVLPDEEMELMAEKF 210 >2IRP-A nrPDB Length = 208 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 51/195 (26%), Positives = 85/195 (43%), Gaps = 24/195 (12%) Query: 7 RQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGEV 66 +++EA L V T GN+SA E + I SG +T +D++++ E V Sbjct: 14 EEIIEAGRILHSRGWVPATSGNISAKVSEEYI-AITASGKHKGKLTPEDILLIDYEGRPV 72 Query: 67 VEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWA----------QAGQSIPATGT 116 G KPS++T H +Y+ FP + +VHTHS +AT+ + + + + A Sbjct: 73 --GGGKPSAETLLHTTVYKLFPEVNAVVHTHSPNATVISIVEKKDFVELEDYELLKAFPD 130 Query: 117 THADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAW 176 H IP + + + VE + K D G L+ HG + W Sbjct: 131 IHTHEVKIKIPIFPNEQNIPLLAKE--------VENYFKTSEDKY---GFLIRGHGLYTW 179 Query: 177 GKNAEDAVHNAIVLE 191 G++ E+A+ + LE Sbjct: 180 GRSMEEALIHTEALE 194 >1E4A-P nrPDB Length = 214 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 5/124 (4%) Query: 5 LKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETG 64 L RQ+++ L + + L T GNVS R + +I P+G+ Y +T +V + G Sbjct: 6 LARQIIDTCLEMTRLGLNQGT-GNVSV--RYQDGMLITPTGIPYEKLTESHIVFID-GNG 61 Query: 65 EVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYG 124 + EG K PSS+ H YQ+ P +VH H+ H T + +SIPA A Sbjct: 62 KHEEG-KLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVSILNRSIPAIHYMIAAAGGN 120 Query: 125 TIPC 128 +IPC Sbjct: 121 SIPC 124 >4XXF-A nrPDB Length = 258 Score = 50.8 bits (120), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 22/161 (13%) Query: 39 FVIKPSGVDYSVMTADDMVVVSIETGEVVEGTKKPS-----SDTPTHRLLYQAFPSIGGI 93 F + P G+ + +MT D+++V+ E G V+ G K+ + H +++A P + I Sbjct: 57 FWVNPFGLAFRLMTVSDLILVNQE-GTVIGGGKEGRRIVNLAGFMIHSAIHKARPEVQAI 115 Query: 94 VHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETF 153 H+HS + ++ G+ + T T + FYG D + G++ G V++E Sbjct: 116 CHSHSTYGKAFSSLGKPLAIT-TQDSCAFYG---------DVALLGDF----GGVVIEEK 161 Query: 154 EKQGIDAA--QMPGVLVHSHGPFAWGKNAEDAVHNAIVLEE 192 E I A Q +++ +HG G + AV I+LE+ Sbjct: 162 ESGTIAVALQQKKAIILQNHGLLTVGTTIDSAVAWFIMLEK 202 >1PVT-A nrPDB Length = 238 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 41/148 (27%), Positives = 65/148 (43%), Gaps = 21/148 (14%) Query: 65 EVVEGTKKPSSDTPTHRLLYQAF----PSIGGIVHTHSRHATIWA---QAGQSIPATGTT 117 E++ G KP+S+ PTH +++ F P IVHTH + + + +P Sbjct: 91 EILHGNGKPTSEFPTHLMIHAKFKEMNPEKKAIVHTHPLNLLTLMNLEEFQELLPKMMKI 150 Query: 118 HADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEK-QGIDAAQMPGVLVHSHGPFAW 176 H + P + + E G E + ++T EK +G DA VL HG A+ Sbjct: 151 HPEVLI-FFPQGISVVEFEKPGSVE-----LGLKTVEKSEGKDA-----VLWDKHGVVAF 199 Query: 177 GKNAEDAVHNAIVLEEVAYMGIFCRQLA 204 GK+ +A +LE+ A I R L+ Sbjct: 200 GKDVAEAYDRVEILEKAA--EILLRVLS 225 >2Z7B-A nrPDB Length = 270 Score = 35.4 bits (80), Expect = 0.023, Method: Compositional matrix adjust. Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 26/201 (12%) Query: 5 LKRQVLEANLALPKHNL---VTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSI 61 ++R+V E + K L + T+G++SA D E + S++T DD+ ++ Sbjct: 37 MRRKVFEELVTATKILLNEGIMDTFGHISARDPEDPASFFLAQKLAPSLITVDDIQRFNL 96 Query: 62 ETGEVVEGTKKPSS-DTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHAD 120 + GE + +PS + H +Y+ P + ++HTHS + P TH Sbjct: 97 D-GETSD--NRPSYLERYIHSEIYKTRPDVQCVLHTHS--PAVLPYCFVDTPLRPVTHMG 151 Query: 121 YFYG-TIPCTRKMTDAEINGEYEWETG------NVIVETFEKQGIDAAQMPGVLVHSHGP 173 F G ++P EI ++ ET +V + E G VL+ HG Sbjct: 152 AFIGESVPVY------EIRDKHGDETDLFGGSPDVCADIAESLGSQTV----VLMARHGV 201 Query: 174 FAWGKNAEDAVHNAIVLEEVA 194 GK+ + V A LE+ A Sbjct: 202 VNVGKSVREVVFRAFYLEQEA 222 >4M6R-A nrPDB Length = 224 Score = 33.9 bits (76), Expect = 0.066, Method: Compositional matrix adjust. Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 31/180 (17%) Query: 22 VTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIE----TGEVVEGTKKPSSDT 77 VT T G +S + I PSGV + +DM V I +G K S T Sbjct: 23 VTGTGGGISL--KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCT 80 Query: 78 PTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPAT--GTTHADYFYGTIPCTRKMTDA 135 P Y G ++HTHS+ A + A P TH + G CT Sbjct: 81 PLFMNAY-TMRGAGAVIHTHSKAAVM---ATLLFPGREFKITHQEMIKGIKKCTS----- 131 Query: 136 EINGEYEWETGNV--IVETFEKQGIDAAQMP----------GVLVHSHGPFAWGKNAEDA 183 G Y ++ V I+E ++ +M VLV HG + WG+ E A Sbjct: 132 --GGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKA 189 >4PIC-A nrPDB Length = 156 Score = 30.4 bits (67), Expect = 0.69, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 145 TGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEE 192 TGN ++ Q+PGV V S G FA + +E +VH +VL+E Sbjct: 10 TGNTCRSPMAAALLENKQLPGVEVKSAGVFA-AEGSEASVHAKMVLKE 56 >6GCS-A nrPDB Length = 728 Score = 30.4 bits (67), Expect = 0.75, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 6/64 (9%) Query: 98 SRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAE--ING-EYEWETGNVIVETFE 154 SR+ + +A+AG PAT +TH F + R++ + E I+G + E G+ +++ E Sbjct: 3 SRNLSKFARAGLIRPATTSTHTRLFSVS---ARRLAEIELTIDGHKVSIEAGSALIQACE 59 Query: 155 KQGI 158 K G+ Sbjct: 60 KAGV 63 >6J5C-A nrPDB Length = 401 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 13/89 (14%) Query: 135 AEING-EYEWETGNVIVETFEKQGIDAAQMPGVL--VHSHGPFAWGKNAEDAVHNAIVLE 191 A I G +Y ++G+V E G++ +M G+ + FAW + D+ H+ +V+ Sbjct: 274 AHIEGNKYHLKSGHVTCEV----GLEKLKMKGLTYTMCDKSKFAWKRTPTDSGHDTVVM- 328 Query: 192 EVAYMG-----IFCRQLAPQLPDMQQTLL 215 EV + G I R +A PD+ +L Sbjct: 329 EVTFSGSKPCRIPVRAVAHGSPDVNVAML 357 >3JRW-A nrPDB Length = 587 Score = 28.5 bits (62), Expect = 2.2, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 20/27 (74%), Gaps = 1/27 (3%) Query: 174 FAWGKNAEDAVHNAIV-LEEVAYMGIF 199 F+WG+N E+A+ N +V L+E++ G F Sbjct: 500 FSWGENREEAISNMVVALKELSIRGDF 526 >2YL2-A nrPDB Length = 540 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 20/27 (74%), Gaps = 1/27 (3%) Query: 174 FAWGKNAEDAVHNAIV-LEEVAYMGIF 199 F+WG+N E+A+ N +V L+E++ G F Sbjct: 484 FSWGENREEAISNMVVALKELSIRGDF 510 >5CWW-B nrPDB Length = 595 Score = 27.3 bits (59), Expect = 5.4, Method: Compositional matrix adjust. Identities = 13/53 (24%), Positives = 25/53 (47%), Gaps = 5/53 (9%) Query: 145 TGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMG 197 TG +E + + PG++ GPF + N ED + + L+++ +G Sbjct: 349 TGEATIEVYTR-----PSRPGLVPKLQGPFDFDLNPEDEQDDEVELKDIYVIG 396 >1K8Q-A nrPDB Length = 377 Score = 27.3 bits (59), Expect = 5.5, Method: Compositional matrix adjust. Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 7/75 (9%) Query: 121 YFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVH------SHGPF 174 +++ ++P +TD + W GN ++ + +++P ++ H +H F Sbjct: 298 HYHQSMPPYYNLTDMHVPIAV-WNGGNDLLADPHDVDLLLSKLPNLIYHRKIPPYNHLDF 356 Query: 175 AWGKNAEDAVHNAIV 189 W +A AV+N IV Sbjct: 357 IWAMDAPQAVYNEIV 371 >2Z8S-A nrPDB Length = 591 Score = 27.3 bits (59), Expect = 6.4, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 37/88 (42%), Gaps = 20/88 (22%) Query: 90 IGGIVHTHSRHATIWAQAGQSI----PATGTTHADYFYGTIPCTRKMTDAEINGEYE--- 142 + G S A++WAQ S+ PA GTT Y + D + +G+YE Sbjct: 73 VNGTEQPASEKASVWAQPYHSVPLDKPAGGTTPKGESYTYSANDASVGDVDGDGQYELIL 132 Query: 143 -WE------------TGNVIVETFEKQG 157 W+ TG+V+++ ++ G Sbjct: 133 KWDPSNSKDNSQDGYTGDVLIDAYKLDG 160 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1K0W-A nrPDB 364 e-101 4C25-A nrPDB 218 1e-57 2IRP-A nrPDB 195 2e-50 1E4A-P nrPDB 171 2e-43 4XXF-A nrPDB 163 6e-41 Sequences not found previously or not previously below threshold: 4M6R-A nrPDB 70 8e-13 2Z7B-A nrPDB 65 3e-11 1PVT-A nrPDB 65 3e-11 2OPI-A nrPDB 58 4e-09 3AHE-A nrPDB 31 0.40 2PXX-A nrPDB 29 1.4 4N0Q-A nrPDB 29 1.9 4ZYN-A nrPDB 28 2.8 5AX7-A nrPDB 28 4.1 4QDI-A nrPDB 27 4.4 >1K0W-A nrPDB Length = 231 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 227/231 (98%), Positives = 230/231 (99%) Query: 1 MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVS 60 MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYS+MTADDMVVVS Sbjct: 1 MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSIMTADDMVVVS 60 Query: 61 IETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHAD 120 IETGEVVEG KKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHA+ Sbjct: 61 IETGEVVEGAKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHAN 120 Query: 121 YFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNA 180 YFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNA Sbjct: 121 YFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNA 180 Query: 181 EDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ 231 EDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLL+KHYLRKHGAKAYYGQ Sbjct: 181 EDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLNKHYLRKHGAKAYYGQ 231 >4C25-A nrPDB Length = 212 Score = 218 bits (556), Expect = 1e-57, Method: Composition-based stats. Identities = 64/227 (28%), Positives = 108/227 (47%), Gaps = 35/227 (15%) Query: 4 DLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIET 63 D+K+++++ L + +L T GN+S DRE+ + I PSG+D+ + D+VV+ I Sbjct: 8 DVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDI-N 66 Query: 64 GEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFY 123 G VVEG + PSS+ H + YQ I I+H H+ +AT+ A + +PA + Y Sbjct: 67 GNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVLACLREPLPA-----SHYMI 121 Query: 124 GTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQ----MPGVLVHSHGPFAWGKN 179 ++ + G E ++AA+ VL+ +HG A +N Sbjct: 122 AVAGKDVRVAEYATYGTKEL-------------AVNAAKAMEGRRAVLLANHGILAGAQN 168 Query: 180 AEDAVHNAIVLEEVAYMG-IFCRQLAPQ------LPDMQQTLLDKHY 219 +A + ++EEV Y I+C LA LPD + L+ + + Sbjct: 169 LLNAFN---IVEEVEYCAKIYC--LAKNFGEPVVLPDEEMELMAEKF 210 >2IRP-A nrPDB Length = 208 Score = 195 bits (494), Expect = 2e-50, Method: Composition-based stats. Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 24/200 (12%) Query: 7 RQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGEV 66 +++EA L V T GN+SA E + I SG +T +D++++ E V Sbjct: 14 EEIIEAGRILHSRGWVPATSGNISAKVSEEYI-AITASGKHKGKLTPEDILLIDYEGRPV 72 Query: 67 VEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWA----------QAGQSIPATGT 116 G KPS++T H +Y+ FP + +VHTHS +AT+ + + + + A Sbjct: 73 --GGGKPSAETLLHTTVYKLFPEVNAVVHTHSPNATVISIVEKKDFVELEDYELLKAFPD 130 Query: 117 THADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAW 176 H IP + + + VE + K D G L+ HG + W Sbjct: 131 IHTHEVKIKIPIFPNEQNIPLLAKE--------VENYFKTSEDKY---GFLIRGHGLYTW 179 Query: 177 GKNAEDAVHNAIVLEEVAYM 196 G++ E+A+ + LE + Sbjct: 180 GRSMEEALIHTEALEFIFEC 199 >1E4A-P nrPDB Length = 214 Score = 171 bits (433), Expect = 2e-43, Method: Composition-based stats. Identities = 57/218 (26%), Positives = 88/218 (40%), Gaps = 21/218 (9%) Query: 5 LKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETG 64 L RQ+++ L + + L T GNVS R + +I P+G+ Y +T +V + G Sbjct: 6 LARQIIDTCLEMTRLGLNQGT-GNVSV--RYQDGMLITPTGIPYEKLTESHIVFID-GNG 61 Query: 65 EVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYG 124 + EG K PSS+ H YQ+ P +VH H+ H T + +SIPA A Sbjct: 62 KHEEG-KLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVSILNRSIPAIHYMIAAAGGN 120 Query: 125 TIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAV 184 +IPC G E E + L+ HG A N E A+ Sbjct: 121 SIPCAP----YATFGTRELS---------EHVALALKNRKATLLQHHGLIACEVNLEKAL 167 Query: 185 ---HNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHY 219 H VL ++ + P L D + ++ + + Sbjct: 168 WLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKF 205 >4XXF-A nrPDB Length = 258 Score = 163 bits (412), Expect = 6e-41, Method: Composition-based stats. Identities = 54/234 (23%), Positives = 99/234 (42%), Gaps = 25/234 (10%) Query: 5 LKRQVLEANLALPKHNLVTLTWGNVSAVDRE-RGVFVIKPSGVDYSVMTADDMVVVSIET 63 LK +++ A G+++ D E + F + P G+ + +MT D+++V+ E Sbjct: 22 LKERLVAAIRIFANEGFDHTVAGHLTVRDPENKHHFWVNPFGLAFRLMTVSDLILVNQE- 80 Query: 64 GEVVEGTKKPS-----SDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTH 118 G V+ G K+ + H +++A P + I H+HS + ++ G+ + T T Sbjct: 81 GTVIGGGKEGRRIVNLAGFMIHSAIHKARPEVQAICHSHSTYGKAFSSLGKPLAIT-TQD 139 Query: 119 ADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAA--QMPGVLVHSHGPFAW 176 + FYG D + G++ G V++E E I A Q +++ +HG Sbjct: 140 SCAFYG---------DVALLGDF----GGVVIEEKESGTIAVALQQKKAIILQNHGLLTV 186 Query: 177 GKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLP-DMQQTLLDKHYLRKHGAKAYY 229 G + AV I+LE+ + + +P D Q L H Y+ Sbjct: 187 GTTIDSAVAWFIMLEKQCQVQLLADAAGQTIPIDEPQAAFTFKEL-GHEQAGYF 239 >4M6R-A nrPDB Length = 224 Score = 69.9 bits (169), Expect = 8e-13, Method: Composition-based stats. Identities = 44/184 (23%), Positives = 63/184 (34%), Gaps = 13/184 (7%) Query: 9 VLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIE----TG 64 + E VT T G +S + I PSGV + +DM V I +G Sbjct: 10 IPELCKQFYHLGWVTGTGGGISLKHGDE--IYIAPSGVQKERIQPEDMFVCDINEKDISG 67 Query: 65 EVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYG 124 K S TP Y G ++HTHS+ A + A TH + G Sbjct: 68 PSPSKKLKKSQCTPLFMNAYTMR-GAGAVIHTHSK-AAVMATLLFPGREFKITHQEMIKG 125 Query: 125 TIPCTR----KMTDAEINGEYEWETGNVIVETFEKQGIDAAQMP-GVLVHSHGPFAWGKN 179 CT + D + E ++ ++ VLV HG + WG+ Sbjct: 126 IKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGET 185 Query: 180 AEDA 183 E A Sbjct: 186 WEKA 189 >2Z7B-A nrPDB Length = 270 Score = 64.9 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 41/195 (21%), Positives = 74/195 (37%), Gaps = 10/195 (5%) Query: 1 MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVS 60 M + +++ A L ++ T+G++SA D E + S++T DD+ + Sbjct: 37 MRRKVFEELVTATKILLNEGIMD-TFGHISARDPEDPASFFLAQKLAPSLITVDDIQRFN 95 Query: 61 IETGEVVEGTKKPSS-DTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHA 119 ++ +PS + H +Y+ P + ++HTHS + P TH Sbjct: 96 LDG---ETSDNRPSYLERYIHSEIYKTRPDVQCVLHTHSP--AVLPYCFVDTPLRPVTHM 150 Query: 120 DYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKN 179 F G ++ D +G+ G + VL+ HG GK+ Sbjct: 151 GAFIGESVPVYEIRDK--HGDETDLFGGSP-DVCADIAESLGSQTVVLMARHGVVNVGKS 207 Query: 180 AEDAVHNAIVLEEVA 194 + V A LE+ A Sbjct: 208 VREVVFRAFYLEQEA 222 >1PVT-A nrPDB Length = 238 Score = 64.9 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 49/237 (20%), Positives = 82/237 (34%), Gaps = 42/237 (17%) Query: 2 LEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRER-----------GVF---------VI 41 + + R++ + L L GN+S ER F +I Sbjct: 3 MRETIREIQKVAYWLAIKGLSEANAGNISVRLDERPEGYEVKSVNEYGFDYDGPEMYLLI 62 Query: 42 KPSGVDYSVMTADD--MVVVSIETGEVVE---GTKKPSSDTPTHRLLYQAF----PSIGG 92 +G + DD + ++ + G+ E G KP+S+ PTH +++ F P Sbjct: 63 TATGSRMREVYEDDSKICLLHVLPGKHYEILHGNGKPTSEFPTHLMIHAKFKEMNPEKKA 122 Query: 93 IVHTHSRHATI---WAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVI 149 IVHTH + + + +P H P + + E G Sbjct: 123 IVHTHPLNLLTLMNLEEFQELLPKMMKIHP-EVLIFFPQGISVVEFEKPGS--------- 172 Query: 150 VETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQ 206 VE K + VL HG A+GK+ +A +LE+ A + + L Sbjct: 173 VELGLKTVEKSEGKDAVLWDKHGVVAFGKDVAEAYDRVEILEKAAEILLRVLSLGRN 229 >2OPI-A nrPDB Length = 212 Score = 57.9 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 71/199 (35%), Gaps = 19/199 (9%) Query: 25 TWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLY 84 + GN+S E + S V + + + + +I +G G K PS ++ H + Sbjct: 26 SSGNLSWRIGEEALISGTGSWVP--TLAKEKVSICNIASGTPTNGVK-PSMESTFHLGVL 82 Query: 85 QAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWE 144 + P + ++H S +AT + T IPC ++ + Y Sbjct: 83 RERPDVNVVLHFQSEYATAISCMKNKPTNFNVT------AEIPCHVG-SEIPVIPYYRPG 135 Query: 145 TGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEE-----VAYMGIF 199 + E + + VL+ +HG GK+ + A E V G + Sbjct: 136 SP----ELAKAVVEAMLKHNSVLLTNHGQVVCGKDFDQVYERATFFEMACRIIVQSGGDY 191 Query: 200 CRQLAPQLPDMQQTLLDKH 218 ++ D++ +L K Sbjct: 192 SVLTPEEIEDLEIYVLGKK 210 >3AHE-A nrPDB Length = 845 Score = 31.0 bits (68), Expect = 0.40, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 14/72 (19%) Query: 138 NGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMG 197 G G VI E + +D ++ GV + HG WG+ +E +G Sbjct: 391 IGANPNANGGVIREDLKLPELDQYEVTGVKEYGHG---WGQ-----------VEAPRALG 436 Query: 198 IFCRQLAPQLPD 209 +CR + PD Sbjct: 437 AYCRDIIKNNPD 448 >2PXX-A nrPDB Length = 215 Score = 29.4 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 38/113 (33%), Gaps = 14/113 (12%) Query: 123 YGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFA-----WG 177 Y ++ + WET +V F D G L A W Sbjct: 73 YSSVVVAAMQACYAHVPQLRWETMDVRKLDFPSASFDVVLEKGTL---DALLAGERDPWT 129 Query: 178 KNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYG 230 ++E VL EV+ R L P + T H+ +H A+AYYG Sbjct: 130 VSSEGVHTVDQVLSEVS------RVLVPGGRFISMTSAAPHFRTRHYAQAYYG 176 >4N0Q-A nrPDB Length = 354 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 26/173 (15%), Positives = 53/173 (30%), Gaps = 11/173 (6%) Query: 6 KRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGE 65 Q++ + + T VS V E GV ++ P+ T D+ +E Sbjct: 70 ANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTA------TGPDLTARGLENVF 123 Query: 66 VVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGT 125 G ++ +L ++H + A A ++ G ++ Sbjct: 124 RTCGRDGQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSV 183 Query: 126 IPCTRK----MTDAEINGEYEWETGNVIVE-TFEKQGIDAAQMPGVLVHSHGP 173 P + +T + G G E + + A M +++ G Sbjct: 184 TPGDKDFSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGL 236 >4ZYN-A nrPDB Length = 425 Score = 28.3 bits (61), Expect = 2.8, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 22/57 (38%), Gaps = 8/57 (14%) Query: 80 HRLLYQAFPSIGGIVH--------THSRHATIWAQAGQSIPATGTTHADYFYGTIPC 128 H + IVH +H +A+ ++A + A T H+ + Y PC Sbjct: 58 HLTVQNCDLEQQSIVHIVQRPQRKSHETNASGGSEAARGPAAKPTYHSFFVYCKGPC 114 >5AX7-A nrPDB Length = 348 Score = 27.9 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 20/53 (37%), Gaps = 4/53 (7%) Query: 6 KRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVV 58 ++Q+LE L N + DR+ F + G V+ D+V Sbjct: 142 EQQLLEQASILYAENPNI----TLVTRDRQSYGFAVDAFGKHNEVLLTPDIVF 190 >4QDI-A nrPDB Length = 472 Score = 27.5 bits (59), Expect = 4.4, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 24/60 (40%) Query: 45 GVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIW 104 G D + + D +V V +EG S+ + +A P + ++ TH + + Sbjct: 392 GRDLAELPLDHIVAVGQFASAALEGAGLHSTKLKAFQTQAEALPFLINLIQTHQPQSMSF 451 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.121 0.302 Lambda K H 0.267 0.0374 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,104,501 Number of Sequences: 36641 Number of extensions: 295527 Number of successful extensions: 844 Number of sequences better than 10.0: 16 Number of HSP's better than 10.0 without gapping: 17 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 801 Number of HSP's gapped (non-prelim): 39 length of query: 231 length of database: 10,336,785 effective HSP length: 94 effective length of query: 137 effective length of database: 6,892,531 effective search space: 944276747 effective search space used: 944276747 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 57 (26.7 bits)