BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08200 (416 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1AI3-A nrPDB 852 0.0 5M2E-A nrPDB 693 0.0 6C0E-A nrPDB 664 0.0 3DMS-A nrPDB 651 0.0 1HQS-A nrPDB 571 e-163 2D4V-A nrPDB 535 e-152 2IV0-A nrPDB 461 e-130 2E5M-A nrPDB 401 e-112 1XGV-A nrPDB 377 e-105 2D1C-A nrPDB 210 1e-54 5YVT-A nrPDB 176 2e-44 3BLV-B nrPDB 168 5e-42 3ASJ-A nrPDB 156 1e-38 1WPW-A nrPDB 134 6e-32 3TY3-A nrPDB 125 4e-29 4Y1P-A nrPDB 124 6e-29 3BLX-A nrPDB 124 8e-29 2G4O-A nrPDB 117 1e-26 5HN5-A nrPDB 116 2e-26 1VLC-A nrPDB 108 4e-24 1A05-A nrPDB 104 8e-23 5GRH-B nrPDB 103 1e-22 3U1H-A nrPDB 102 3e-22 3FMX-X nrPDB 100 9e-22 1XAD-A nrPDB 98 6e-21 1IDM-A nrPDB 97 2e-20 1V5B-A nrPDB 95 4e-20 5J32-A nrPDB 89 4e-18 3VMJ-A nrPDB 84 9e-17 4IWH-A nrPDB 83 2e-16 1CNZ-A nrPDB 82 6e-16 3VMK-A nrPDB 81 8e-16 1CM7-A nrPDB 81 8e-16 3VML-A nrPDB 75 4e-14 3UDO-A nrPDB 71 7e-13 1ZOR-A nrPDB 57 2e-08 5I96-A nrPDB 47 2e-05 4HCX-A nrPDB 47 2e-05 4AOY-A nrPDB 45 5e-05 3US8-A nrPDB 44 2e-04 6BL1-B nrPDB 34 0.094 2UXQ-A nrPDB 34 0.12 2QFY-A nrPDB 31 1.1 5FIP-A nrPDB 30 2.9 4JGT-A nrPDB 29 3.4 2NVK-X nrPDB 28 5.8 5FV0-A nrPDB 28 7.1 3MT5-A nrPDB 28 8.2 3NAF-A nrPDB 28 8.7 >1AI3-A nrPDB Length = 416 Score = 852 bits (2200), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/416 (100%), Positives = 416/416 (100%) Query: 1 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE 60 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE Sbjct: 1 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE 60 Query: 61 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ 120 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ Sbjct: 61 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ 120 Query: 121 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR 180 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR Sbjct: 121 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR 180 Query: 181 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA 240 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA Sbjct: 181 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA 240 Query: 241 FKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA 300 FKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA Sbjct: 241 FKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA 300 Query: 301 CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA 360 CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA Sbjct: 301 CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA 360 Query: 361 EMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 EMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM Sbjct: 361 EMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 >5M2E-A nrPDB Length = 418 Score = 693 bits (1789), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/414 (78%), Positives = 370/414 (89%), Gaps = 1/414 (0%) Query: 4 KVVVPAQGKKITLQ-NGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERK 62 K+ VPA G KIT+ + L+VP+NPIIP+IEGDGIGVD++P M+KVVDAAVEKAYKGERK Sbjct: 5 KIQVPATGDKITVNADMSLSVPKNPIIPFIEGDGIGVDISPVMIKVVDAAVEKAYKGERK 64 Query: 63 ISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQEL 122 I+WME+Y GEK+TQVY QD WLP ETLD +R+Y V+IKGPLTTPVGGGIRSLNVALRQ+L Sbjct: 65 IAWMEVYAGEKATQVYDQDTWLPQETLDAVRDYVVSIKGPLTTPVGGGIRSLNVALRQQL 124 Query: 123 DLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREE 182 DLY+C RPVR+++G PSPVK P DMVIFRENSEDIYAG+EWKA S +AEKVIKFL EE Sbjct: 125 DLYVCQRPVRWFEGVPSPVKKPGDVDMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEE 184 Query: 183 MGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFK 242 MGVKKIRF E+CGIGIKP S+EGTKRLVR A++YA+ NDR SVTLVHKGNIMKFTEGAFK Sbjct: 185 MGVKKIRFTENCGIGIKPVSQEGTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFK 244 Query: 243 DWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACM 302 DWGY++AR+EFG EL+DGGPW++ KNP TGK +V+KDVIADA LQQILLRPAEYDVIA + Sbjct: 245 DWGYEVARDEFGAELLDGGPWMQFKNPKTGKNVVVKDVIADAMLQQILLRPAEYDVIATL 304 Query: 303 NLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEM 362 NLNGDY+SDALAA+VGGIGIAPGAN+ D A+FEATHGTAPKYAGQDKVNPGS+ILSAEM Sbjct: 305 NLNGDYLSDALAAEVGGIGIAPGANLSDSVAMFEATHGTAPKYAGQDKVNPGSLILSAEM 364 Query: 363 MLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 MLRHMGWTEAADLI+KG GAI AKTVTYDFERLMDGA LL CSEFGDA+I M Sbjct: 365 MLRHMGWTEAADLIIKGTNGAIAAKTVTYDFERLMDGATLLSCSEFGDAMIAKM 418 >6C0E-A nrPDB Length = 419 Score = 664 bits (1712), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/414 (75%), Positives = 365/414 (88%), Gaps = 1/414 (0%) Query: 4 KVVVPAQGKKITLQ-NGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERK 62 K+ VPAQG+ IT+ + L+VP+NPIIP+IEGDGIGVDVTP M++VVDAAV+KAY +RK Sbjct: 6 KIKVPAQGEAITVAADHSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRK 65 Query: 63 ISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQEL 122 ISWME+Y GEK+T+VYG D WLP ETLD +++Y V+IKGPLTTPVGGGIRSLNVA+RQ++ Sbjct: 66 ISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDM 125 Query: 123 DLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREE 182 DLY+CLRP+RY+ G PSPV+ P TDMVIFRENSEDIYAGIEW+AD+ +A+KVI+FL +E Sbjct: 126 DLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKE 185 Query: 183 MGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFK 242 MGVKKIRFPEHCGIG+KP S EGT RLV+AAI+YAI NDR +VTLVHKGNIMKFTEGAFK Sbjct: 186 MGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFK 245 Query: 243 DWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACM 302 DWGYQ+AR+ FG + GGPW++ KNP TGK+I+I DVIADAFLQQILLRP +Y VIA + Sbjct: 246 DWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATL 305 Query: 303 NLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEM 362 NLNGDYISDALAAQVGGIGIAPGANI D+ A+FEATHGTAPKYAGQ+KVNPGSIILSAEM Sbjct: 306 NLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEM 365 Query: 363 MLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 MLRHMGW EAADLI++GMEGAI AKTVTYDFER M GA L+ S F DA+I++M Sbjct: 366 MLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 419 >3DMS-A nrPDB Length = 427 Score = 651 bits (1679), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/413 (75%), Positives = 356/413 (86%), Gaps = 1/413 (0%) Query: 5 VVVPAQGKKITL-QNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKI 63 + VP G KIT+ ++ LNV + PIIPYIEGDG G D+TP M+KVVDAAVEKAY G++KI Sbjct: 14 IKVPEGGDKITVNKDFSLNVSDQPIIPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKKI 73 Query: 64 SWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELD 123 WMEIY GEK+T+VYG DVWLP ETL +++EY V+IKGPLTTPVGGGIRSLNVALRQELD Sbjct: 74 HWMEIYAGEKATKVYGPDVWLPEETLQVLKEYVVSIKGPLTTPVGGGIRSLNVALRQELD 133 Query: 124 LYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEM 183 LY+CLRP++Y++G PSPV+ PE T+MVIFRENSEDIYAGIEW A+S A+KVIKFL+EEM Sbjct: 134 LYVCLRPIQYFKGVPSPVREPEKTNMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEEM 193 Query: 184 GVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKD 243 GVKKIRFP+ GIGIKP S+EGT+RLVR AI+YAI NDR SVTLVHKGNIMKFTEGAF+D Sbjct: 194 GVKKIRFPQTSGIGIKPVSKEGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFRD 253 Query: 244 WGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMN 303 GY LA++EFG ELIDGGPW+K KNP TG EIV+KD IADAFLQQILLRPAEYDVIA +N Sbjct: 254 AGYALAQKEFGAELIDGGPWMKFKNPKTGNEIVVKDSIADAFLQQILLRPAEYDVIATLN 313 Query: 304 LNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMM 363 LNGDYISDALAAQVGGIGIAPGAN+ D A+FEATHGTAPKYAG+D VNPGS ILSAEMM Sbjct: 314 LNGDYISDALAAQVGGIGIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSEILSAEMM 373 Query: 364 LRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 LRH+GWTEAAD+I+ ME +I K VTYDF RLM+GA + CS FG +IENM Sbjct: 374 LRHLGWTEAADVIISAMEKSIKQKRVTYDFARLMEGATQVSCSGFGQVLIENM 426 >1HQS-A nrPDB Length = 423 Score = 571 bits (1472), Expect = e-163, Method: Compositional matrix adjust. Identities = 282/423 (66%), Positives = 332/423 (78%), Gaps = 17/423 (4%) Query: 9 AQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEI 68 AQG+KIT+ NG LNVP NPIIP+IEGDG G D+ A KV++AAVEKAYKGE+KI+W E+ Sbjct: 2 AQGEKITVSNGVLNVPNNPIIPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEV 61 Query: 69 YTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICL 128 Y GEK+ G+ WLPAETLD+IREY +AIKGPLTTPVGGGIRSLNVALRQELDL++CL Sbjct: 62 YAGEKAYNKTGE--WLPAETLDVIREYFIAIKGPLTTPVGGGIRSLNVALRQELDLFVCL 119 Query: 129 RPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKI 188 RPVRY+ G PSPVK PE TDMVIFREN+EDIYAGIE+ S + +K+I FL+ E+ V KI Sbjct: 120 RPVRYFTGVPSPVKRPEDTDMVIFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNKI 179 Query: 189 RFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQL 248 RFPE GIGIKP SEEGT RLVRAAI+YAI + R SVTLVHKGNIMKFTEGAFK+WGY+L Sbjct: 180 RFPETSGIGIKPVSEEGTSRLVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYEL 239 Query: 249 AREEFGGELIDGGPWLKV-------------KNPNTGKEIVIKDVIADAFLQQILLRPAE 295 A +E+G ++ + ++ +I+IKD IAD FLQQIL RP E Sbjct: 240 AEKEYGDKVFTWAQYDRIAEEQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNE 299 Query: 296 YDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDEC--ALFEATHGTAPKYAGQDKVNP 353 +DV+A MNLNGDYISDALAAQVGGIGIAPGANI E A+FEATHGTAPKYAG DKVNP Sbjct: 300 FDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDKVNP 359 Query: 354 GSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAII 413 S+ILS ++L H+GW EAADL++K ME I +K VTYDF RLMDGA +KCSEFG+ +I Sbjct: 360 SSVILSGVLLLEHLGWNEAADLVIKSMEKTIASKVVTYDFARLMDGATEVKCSEFGEELI 419 Query: 414 ENM 416 +NM Sbjct: 420 KNM 422 >2D4V-A nrPDB Length = 429 Score = 535 bits (1377), Expect = e-152, Method: Compositional matrix adjust. Identities = 260/429 (60%), Positives = 315/429 (73%), Gaps = 13/429 (3%) Query: 1 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE 60 M + + PA G +TL NG L VP+ PIIP+IEGDGIG DVTPAM VVDAAV K Y G+ Sbjct: 1 MTTHIQKPATGSPLTLLNGVLQVPDQPIIPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQ 60 Query: 61 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ 120 R+I+WME++ G+K+ Q+YG+ +LP ET+ IREY+VAIKGPL TPVGGGIRSLNVA+RQ Sbjct: 61 RQIAWMELFAGQKAVQLYGEGQYLPDETMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQ 120 Query: 121 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR 180 +LDLY+CLRPVRY++GTPSP++HPE DMVIFRENSEDIYAGIEW A S +AEK+I+FLR Sbjct: 121 DLDLYVCLRPVRYFEGTPSPMRHPEKVDMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLR 180 Query: 181 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA 240 EEMGV KIRFP+ IGIKP S EG++RL+R I+YA+ + + SV+LVHKGNIMKFTEG Sbjct: 181 EEMGVTKIRFPDSSAIGIKPVSTEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGG 240 Query: 241 FKDWGYQLAREEFGGELI---DGGPWLKVKNPNTGK----------EIVIKDVIADAFLQ 287 F+DWGY LA EF G + K + G+ +++IKDVIAD FLQ Sbjct: 241 FRDWGYALAEREFAGRVFTWRQKAAISKAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQ 300 Query: 288 QILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAG 347 QILLRP +Y V+A +NLNGDY+SDALAA+VGGIG+APGAN+ D A+FEATHGTAP AG Sbjct: 301 QILLRPEDYSVVATLNLNGDYVSDALAAEVGGIGMAPGANLSDTHAIFEATHGTAPDIAG 360 Query: 348 QDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSE 407 Q K NP S+ILSA MML H+GW EAA IV M I A VT D L L +E Sbjct: 361 QGKANPSSLILSAVMMLEHLGWGEAAQAIVAAMNATIAAGEVTGDLAALRGDVPALSTTE 420 Query: 408 FGDAIIENM 416 F A+I Sbjct: 421 FTAALIRRF 429 >2IV0-A nrPDB Length = 412 Score = 461 bits (1187), Expect = e-130, Method: Compositional matrix adjust. Identities = 236/414 (57%), Positives = 301/414 (72%), Gaps = 10/414 (2%) Query: 4 KVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKI 63 KV P G+KI +NGKL VP+NPIIPY EGDGIG DV PA ++V+DAA +K K ++ Sbjct: 5 KVKPPENGEKIRYENGKLIVPDNPIIPYFEGDGIGKDVVPAAIRVLDAAADKIGK---EV 61 Query: 64 SWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELD 123 W ++Y GE + ++YG +LP +TL+ I+E+RVA+KGPLTTPVGGG RSLNV +RQ LD Sbjct: 62 VWFQVYAGEDAYKLYGN--YLPDDTLNAIKEFRVALKGPLTTPVGGGYRSLNVTIRQVLD 119 Query: 124 LYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEM 183 LY +RPV Y +G PSP+KHPE + VIFREN+ED+YAGIEW S +A K+I+FL+ E Sbjct: 120 LYANVRPVYYLKGVPSPIKHPEKVNFVIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEF 179 Query: 184 GVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKD 243 GV IR E GIGIKP SE TKRLVR AI YAI N+R SVTLVHKGNIMK+TEGAF+D Sbjct: 180 GVT-IR--EDSGIGIKPISEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRD 236 Query: 244 WGYQLAREEFGGELI-DGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACM 302 WGY++A++EFG I + W K +IV+KD IAD QQIL R EYDVIA Sbjct: 237 WGYEVAKQEFGEYCITEDELWDKYGGKQPEGKIVVKDRIADNMFQQILTRTDEYDVIALP 296 Query: 303 NLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEM 362 NLNGDY+SDA AA +GG+GIAPG+NIGD +FE HG+APKYAGQ+KVNP + IL+ + Sbjct: 297 NLNGDYLSDAAAALIGGLGIAPGSNIGDGIGVFEPVHGSAPKYAGQNKVNPTAEILTGAL 356 Query: 363 MLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 M ++GW +A+++I K +E I++ VTYD R M G K + EF +A++EN+ Sbjct: 357 MFEYIGWKDASEMIKKAVEMTISSGIVTYDIHRHMGGTK-VGTREFAEAVVENL 409 >2E5M-A nrPDB Length = 409 Score = 401 bits (1031), Expect = e-112, Method: Compositional matrix adjust. Identities = 204/409 (49%), Positives = 279/409 (68%), Gaps = 8/409 (1%) Query: 8 PAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWME 67 P G+KI GK VP P+I YIEGDGIG ++T A +KV++ AVE+AY R+I W+E Sbjct: 6 PEDGEKIKFDKGKWIVPNKPVILYIEGDGIGPEITNAAIKVINKAVERAYGSSREIKWLE 65 Query: 68 IYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYIC 127 +Y GEK+ ++ P ET +++ +YRV +KGPL TP+G G +S+NVA+R LDLY Sbjct: 66 VYAGEKAEKLVNDR--FPKETQEMLLKYRVVLKGPLETPIGKGWKSVNVAIRLMLDLYAN 123 Query: 128 LRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKK 187 +RPV+Y +G SP+KHPE DM+IFREN++D+Y GIE+ +S +A+K+ FLR+E+ K Sbjct: 124 IRPVKYIEGLESPLKHPEKVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKEL---K 180 Query: 188 IRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQ 247 + + GIGIK S+ T+R+ R AI+YAI + R VT++HKGN+MK+TEGAF++W Y+ Sbjct: 181 VEIEDDTGIGIKVMSKYKTQRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWAYE 240 Query: 248 LAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGD 307 +A +E+ + I + P+ GK I++ D IAD QQI++RP EYD+I N+NGD Sbjct: 241 VALKEYR-DFIVTEEEINQGKPDQGK-IILNDRIADNMFQQIIIRPEEYDIILAPNVNGD 298 Query: 308 YISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHM 367 YISDA A +G IG+ GANIGDE +FEA HGTAPKYAG++ NP II + E+MLR M Sbjct: 299 YISDAAGALIGNIGMLGGANIGDEGGMFEAIHGTAPKYAGKNVANPTGIIKAGELMLRWM 358 Query: 368 GWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 GW EAADLI K + AI K VT D R M G K L E+ D +I+ M Sbjct: 359 GWNEAADLIEKAINMAIRDKKVTQDIARFM-GVKALGTKEYADELIKIM 406 >1XGV-A nrPDB Length = 435 Score = 377 bits (969), Expect = e-105, Method: Compositional matrix adjust. Identities = 201/411 (48%), Positives = 270/411 (65%), Gaps = 14/411 (3%) Query: 8 PAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWME 67 P G + G L VP+NP++ +I GDG+G +V + LKVVDAAV+K Y G R+I W E Sbjct: 17 PPGGSLVEYSGGSLRVPDNPVVAFIRGDGVGPEVVESALKVVDAAVKKVYGGSRRIVWWE 76 Query: 68 IYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYIC 127 + G + + G+ LP TL+ IR RVA+KGPL TPVG G RSLNVA+RQ LDLY Sbjct: 77 LLAGHLAREKCGE--LLPKATLEGIRLARVALKGPLETPVGTGYRSLNVAIRQALDLYAN 134 Query: 128 LRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKK 187 +RPVRYY G P+P K+ + DMVIFREN+ED+YAGIEW DS +A ++ +FL EE G+ Sbjct: 135 IRPVRYY-GQPAPHKYADRVDMVIFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGIS- 192 Query: 188 IRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQ 247 IR E GIG+KP S T+RL+ A+E+A+ N VT++HKGNIMK+TEGAF W Y+ Sbjct: 193 IR--EDAGIGVKPISRFATRRLMERALEWALRNGNTVVTIMHKGNIMKYTEGAFMRWAYE 250 Query: 248 LAREEFGGELIDGGPWLKVKNPNTG----KEIVIKDVIADAFLQQILLRPAEYDVIACMN 303 +A E+F ++ +V+ G +I++ D IAD LQQI+ RP +Y VI N Sbjct: 251 VALEKFREHVVTEQ---EVQEKYGGVRPEGKILVNDRIADNMLQQIITRPWDYQVIVAPN 307 Query: 304 LNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMM 363 LNGDYISDA +A VGGIG+A G N+GD A+ E HGTAPKYAG+D +NP + ILSA ++ Sbjct: 308 LNGDYISDAASALVGGIGMAAGMNMGDGIAVAEPVHGTAPKYAGKDLINPSAEILSASLL 367 Query: 364 L-RHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAII 413 + MGW E ++ + A+ +K VT D R M G + L+ SE+ + +I Sbjct: 368 IGEFMGWREVKSIVEYAIRKAVQSKKVTQDLARHMPGVQPLRTSEYTETLI 418 >2D1C-A nrPDB Length = 496 Score = 210 bits (534), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 146/408 (35%), Positives = 212/408 (51%), Gaps = 61/408 (14%) Query: 14 ITLQNGK-LNVPEN--PIIPYIEGDGIGVDVTPAMLKVVDAA-VEKAYKGERKISWMEIY 69 IT + GK ++V E+ +I I GDGIG + A LKV++AA AY E+ Sbjct: 4 ITTETGKKMHVLEDGRKLITVIPGDGIGPECVEATLKVLEAAKAPLAY---------EVR 54 Query: 70 TGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLR 129 S G +P ET++ IR+ RV +KGPL TPVG G +S NV LR+ + Y +R Sbjct: 55 EAGASVFRRGIASGVPQETIESIRKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVR 114 Query: 130 PVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIR 189 PVR + P+P + D+V+ REN ED+YAGIE + A+ Sbjct: 115 PVREFPNVPTPYAGRGI-DLVVVRENVEDLYAGIEHMQTPSVAQT--------------- 158 Query: 190 FPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLA 249 +K S +G++++VR A E A A R V K NIMK EG K Q+A Sbjct: 159 --------LKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVA 210 Query: 250 REEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYI 309 +E +I +I D Q++ RP +++VI N+NGD + Sbjct: 211 QEY--------------------PDIEAVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDIL 250 Query: 310 SDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGW 369 SD + +GG+G AP ANIG+E A+FEA HG+APKYAG++ +NP +++LSA MMLR++ Sbjct: 251 SDLTSGLIGGLGFAPSANIGNEVAIFEAVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEE 310 Query: 370 TEAADLIVKGMEGAI-NAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 ADLI + + + +T D GA K +E+ +AII+N+ Sbjct: 311 FATADLIENALLYTLEEGRVLTGDVVGYDRGA---KTTEYTEAIIQNL 355 >5YVT-A nrPDB Length = 339 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 123/386 (31%), Positives = 189/386 (48%), Gaps = 63/386 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDGIG +++ A++K+ DAA ER ++ + Q G +P+E Sbjct: 7 VTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVT---------AIQGPGGKWMIPSEA 57 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 + + + ++ +KGPL TP+ G S+N+ LR+ DLY +RP +G +P + Sbjct: 58 KESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTD---VN 114 Query: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKR 208 +V REN+E Y+GIE + V++ IK +E +KR Sbjct: 115 IVTIRENTEGEYSGIE----HVIVDGVVQ-------------------SIKLITEGASKR 151 Query: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKN 268 + A EYA N R +VT VHK NIM+ ++G F Q RE Sbjct: 152 IAEFAFEYARNNHRSNVTAVHKANIMRMSDGLF----LQKCREV---------------- 191 Query: 269 PNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANI 328 + K+I ++ D ++ P+++DV+ NL GD +SD A +GG+G+ P NI Sbjct: 192 AESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNI 251 Query: 329 G-DECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAI-NA 386 G + A+FE+ HGTAP AG+D NP +++LSA MMLRHMG + A I I + Sbjct: 252 GANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDG 311 Query: 387 KTVTYDFERLMDGAKLLKCSEFGDAI 412 K++T D KCS+F + I Sbjct: 312 KSLTKDL------GGNAKCSDFTEEI 331 >3BLV-B nrPDB Length = 354 Score = 168 bits (425), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 117/391 (29%), Positives = 186/391 (47%), Gaps = 63/391 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + +IEGDGIG +++ ++ K+ AA I W + S +P Sbjct: 24 VSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDPA 73 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 + I + VA+KGPL TP+G G RSLN+ LR+ L+ +RP + +G + E D Sbjct: 74 VQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENVD 130 Query: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKR 208 +V+ REN+E Y+GIE + IK + + ++R Sbjct: 131 LVLIRENTEGEYSGIEHIVCPGVVQS-----------------------IKLITRDASER 167 Query: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKN 268 ++R A EYA A R V +VHK I + +G F + +L++E Sbjct: 168 VIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEY---------------- 211 Query: 269 PNTGKEIVIKDVIADAFLQQILLRPAEYD--VIACMNLNGDYISDALAA-QVGGIGIAPG 325 ++ ++ + D + +++ P+ Y V C NL GD +SD + G +G+ P Sbjct: 212 ----PDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPS 267 Query: 326 ANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAIN 385 ANIG + ++FEA HG+AP AGQDK NP +++LS+ MML HMG T AD I + A+ Sbjct: 268 ANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQI----QNAVL 323 Query: 386 AKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 + + R D A S F +A+I+ + Sbjct: 324 STIASGPENRTGDLAGTATTSSFTEAVIKRL 354 >3ASJ-A nrPDB Length = 334 Score = 156 bits (395), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 118/360 (32%), Positives = 176/360 (48%), Gaps = 69/360 (19%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I IEGDGIG +V PA +V++A + ++E G ++ + G V P ET Sbjct: 5 ICLIEGDGIGHEVIPAARRVLEAT-------GLPLEFVEAEAGWETFERRGTSV--PEET 55 Query: 89 LDLIREYRVAIKGPLTTPVG------GGIRSLNVALRQELDLYICLRPVRYYQGTPSPVK 142 ++ I + G T+P G IR L R+ LDLY +RP + P P Sbjct: 56 VEKILSCHATLFGAATSPTRKVPGFFGAIRYL----RRRLDLYANVRPAK---SRPVPGS 108 Query: 143 HPELTDMVIFRENSEDIYAGIEWK-ADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPC 201 P + D+VI REN+E +Y E + D A A+ VI Sbjct: 109 RPGV-DLVIVRENTEGLYVEQERRYLDVAIADAVI------------------------- 142 Query: 202 SEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGG 261 S++ ++R+ RAA+ A R ++ + HK N++ T+G F D ++A++ Sbjct: 143 SKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKD---------F 193 Query: 262 PWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIG 321 P + V+ D+I D Q+++RP +DVI NL GD +SD A VGG+G Sbjct: 194 PLVNVQ-----------DIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLG 242 Query: 322 IAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGME 381 +AP NIGD A+FE HG+AP AG+ NP + ILSA MML ++G EAA + K ++ Sbjct: 243 LAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVD 302 >1WPW-A nrPDB Length = 336 Score = 134 bits (338), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 100/363 (27%), Positives = 165/363 (45%), Gaps = 58/363 (15%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I+GDGIG ++ +++ A + + Y I ++E+ G+++ YG+ LP ++ Sbjct: 4 VALIQGDGIGPEIVSKSKRIL-AKINELY--SLPIEYIEVEAGDRALARYGE--ALPKDS 58 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 L +I + + +KGP VG + V LRQ D+Y +RP + G + + D Sbjct: 59 LKIIDKADIILKGP----VGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGN---VD 111 Query: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKR 208 ++I REN+ED+Y G E + +G+K + ++R Sbjct: 112 ILIVRENTEDLYKGFEHIV-----------------------SDGVAVGMKIITRFASER 148 Query: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKN 268 + + + +A+ R VT VHK N+M+ T+G F + R G+ Sbjct: 149 IAKVGLNFALRR-RKKVTCVHKANVMRITDGLFA----EACRSVLKGK------------ 191 Query: 269 PNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANI 328 + ++ DA ++ P +DVI N+ GD +SD + G +GIAP ANI Sbjct: 192 ------VEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDEASQIAGSLGIAPSANI 245 Query: 329 GDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKT 388 GD+ ALFE HG A AG++ NP + +LS MM M D +K NA Sbjct: 246 GDKKALFEPVHGAAFDIAGKNIGNPTAFLLSVSMMYERMYELSNDDRYIKASRALENAIY 305 Query: 389 VTY 391 + Y Sbjct: 306 LVY 308 >3TY3-A nrPDB Length = 366 Score = 125 bits (313), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 108/396 (27%), Positives = 189/396 (47%), Gaps = 50/396 (12%) Query: 28 IIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAE 87 ++ I DGIG +V PA ++++ K + K ++++ G + + G+ LP Sbjct: 12 VLGLIPADGIGKEVVPAARRLME---NLPAKHKLKFDFIDLDAGWGTFERTGK--ALPER 66 Query: 88 TLDLIR-EYRVAIKGPLTTPVG--GGIRSLNVALRQELDLYICLRPVRYYQGTP-SPVKH 143 T++ ++ E A+ G + +P G S VALR+++ LY +RPV+ G PV Sbjct: 67 TVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKGKPV-- 124 Query: 144 PELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSE 203 D+VI REN+E +Y E + ++V + +R R E I + Sbjct: 125 ----DLVIVRENTECLYVKEERMVQNTPGKRVAEAIR--------RISEEASTKIGKMAF 172 Query: 204 E--GTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGG 261 E +++ +R + Y+I + + VT++HK N+M T+G F++ + +D Sbjct: 173 EIAKSRQKIRESGTYSI-HKKPLVTIIHKSNVMSVTDGLFRESCRH-------AQSLD-- 222 Query: 262 PWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIG 321 P+ I + + I D+ + ++ P +DV+ NL GD +SD A+ +G +G Sbjct: 223 -------PSYA-SINVDEQIVDSMVYRLFREPECFDVVVAPNLYGDILSDGAASLIGSLG 274 Query: 322 IAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGME 381 + P AN+GD + E HG+AP AG+ NP + S +ML MG +AA I ++ Sbjct: 275 LVPSANVGDNFVMSEPVHGSAPDIAGRGIANPVATFRSVALMLEFMGHQDAAADIYTAVD 334 Query: 382 GAIN-AKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 + K +T D G K +E DA++ N+ Sbjct: 335 KVLTEGKVLTPDL-----GGK-SGTNEITDAVLANI 364 >4Y1P-A nrPDB Length = 337 Score = 124 bits (312), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 95/340 (27%), Positives = 150/340 (44%), Gaps = 58/340 (17%) Query: 28 IIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAE 87 ++ I+GDGIG +V ++ EK I ++E+ G+ + +G LP + Sbjct: 4 VVALIQGDGIGPEVVSKSKTILARLNEKF---SLPIEYIEVEAGDTTKNKFGD--ALPKD 58 Query: 88 TLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELT 147 +L +I + + +KGP VG + V LR DLY LRP + G + Sbjct: 59 SLRVIEKADMILKGP----VGETAADVVVKLRLMYDLYANLRPAKSLPGLENKFGD---V 111 Query: 148 DMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTK 207 D+++ REN+ED+Y G+E + +GIK + + Sbjct: 112 DILVVRENTEDLYKGLEHV-----------------------ISDGVTVGIKVITRAAST 148 Query: 208 RLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVK 267 R+ + A+ A+ + V VHK N+M+ T+G F + + Sbjct: 149 RIAQVALNQALRRKK-KVVCVHKSNVMRITDGLFAE---------------------SCR 186 Query: 268 NPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGAN 327 N GK + ++ DA ++ P +DVI N GD +SD G +GI+P AN Sbjct: 187 NVLKGK-VEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGISPSAN 245 Query: 328 IGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHM 367 IGD +LFE HG A AG++ NP + +LS MML M Sbjct: 246 IGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRM 285 >3BLX-A nrPDB Length = 349 Score = 124 bits (311), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 94/358 (26%), Positives = 169/358 (47%), Gaps = 60/358 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDG+G ++T ++ + +A I W I + + + V+ E+ Sbjct: 20 VTLIPGDGVGKEITDSVRTIFEAE-------NIPIDWETINIKQTD---HKEGVYEAVES 69 Query: 89 LDLIREYRVAIKGPLTTPVG-GGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELT 147 L + ++ +KG TP G SLNVALR++LD+Y + + +G + + P++ Sbjct: 70 L---KRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRI--PDI- 123 Query: 148 DMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTK 207 D+++ REN+E ++G+E ++ E +K + T+ Sbjct: 124 DLIVIRENTEGEFSGLEHESVPGVVES-----------------------LKVMTRPKTE 160 Query: 208 RLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVK 267 R+ R A ++A +R SVT VHK NIMK +G F++ ++ ++E+ Sbjct: 161 RIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEY-------------- 206 Query: 268 NPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGAN 327 +I + +I D Q + +P ++DV+ ++ G + + AA +GG G+ GAN Sbjct: 207 -----PDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGAN 261 Query: 328 IGDECALFE-ATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAI 384 G + A+FE + GQ+ NP ++ILS+ +ML H+G E A I K + I Sbjct: 262 FGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETI 319 >2G4O-A nrPDB Length = 337 Score = 117 bits (292), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 115/377 (30%), Positives = 164/377 (43%), Gaps = 71/377 (18%) Query: 32 IEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDL 91 I GDGIG +VT +KV+DA V G +K S+ G + G+ LP + Sbjct: 7 IAGDGIGPEVTAEAVKVLDAVV----PGVQKTSY---DLGARRFHATGE--VLPDSVVAE 57 Query: 92 IREYRVAIKGPL---TTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 +R + + G + + P G R L + LR ELD +I LRP R Y G SP+ D Sbjct: 58 LRNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGID 117 Query: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKR 208 V+ RE +E Y G G ++ P + + G +R Sbjct: 118 FVVVREGTEGPYTG-------------------NGGAIRVGTPNEVATEVSVNTAFGVRR 158 Query: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKN 268 +V A E A R +TLVHK N++ F GG WL+ + Sbjct: 159 VVADAFERA-RRRRKHLTLVHKTNVLTFA----------------------GGLWLRTVD 195 Query: 269 ------PNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGI 322 P+ E+ + V DA ++ P +DVI NL GD I+D AA GGIG+ Sbjct: 196 EVGECYPDV--EVAYQHV--DAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGL 251 Query: 323 APGANIGDECA---LFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKG 379 A NI A +FE HG+AP AGQ +P + I+S ++L H+G +AA + + Sbjct: 252 AASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEHDAAARVDR- 310 Query: 380 MEGAINAKTVTYDFERL 396 A+ A T ERL Sbjct: 311 ---AVEAHLATRGSERL 324 >5HN5-A nrPDB Length = 353 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 105/344 (30%), Positives = 152/344 (44%), Gaps = 72/344 (20%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDGIG +V ++V+ KA G + + E G Q G + E Sbjct: 4 VAVIPGDGIGPEVIDGAVRVL-----KAVTGRVRFEYYE--GGVDVFQECGSPIR--EED 54 Query: 89 LDLIREYRVAIKGPLTTPVG-GGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPEL- 146 L+ IR + G TTP G RSL + LR+EL LY LR + P+L Sbjct: 55 LEEIRRSDAVLFGATTTPFDLPGYRSLILTLRKELGLYANLRII------------PDLR 102 Query: 147 --TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEE 204 ++VI RENSE +Y GI + + ++ + E Sbjct: 103 TGREIVIVRENSEGLYFGIGAVVNGR------------------------AVDVRLITRE 138 Query: 205 GTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWL 264 G +R+ R A+E A A +T VHK N++ + F+ ++ RE G E ++ Sbjct: 139 GAERIARFAVEQAKARG-SFITFVHKANVLT-GDKFFR----RIVREVAGEEGVE----- 187 Query: 265 KVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAP 324 ++D I D+F +++ P E+ VI NL GD +SD G IGI P Sbjct: 188 ------------VRDAIIDSFTIKLVRNPWEHGVILSENLFGDILSDLATVHAGSIGIVP 235 Query: 325 GANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMG 368 N GD ALFE HG+AP AG+ NP ILS M+L ++G Sbjct: 236 SGNYGDGIALFEPVHGSAPDIAGKGIANPIGAILSGAMLLDYLG 279 >1VLC-A nrPDB Length = 366 Score = 108 bits (270), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 113/405 (27%), Positives = 177/405 (43%), Gaps = 74/405 (18%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG +V LKV++ +K K K+ + G + +G+ LP ET Sbjct: 15 IAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFG---HIGGDAIDRFGEP--LPEET 69 Query: 89 LDLIREYRVAIKG-----------PLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGT 137 + E G P P GG+ +ALR+ L+LY +RP++ Y+ Sbjct: 70 KKICLEADAIFLGSVGGPKWDDLPPEKRPEIGGL----LALRKMLNLYANIRPIKVYRSL 125 Query: 138 P--SPVKHPEL---TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPE 192 SP+K + D+V RE S +Y G + L EE G + + Sbjct: 126 VHVSPLKEKVIGSGVDLVTVRELSYGVYYGQP------------RGLDEEKGFDTMIY-- 171 Query: 193 HCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 + +R+ R A E A N R VT V K N++ ++ ++ ++ARE Sbjct: 172 ---------DRKTVERIARTAFEIA-KNRRKKVTSVDKANVL-YSSMLWRKVVNEVAREY 220 Query: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 ++ + + D Q++L+P+++DVI N+ GD +SD Sbjct: 221 --------------------PDVELTHIYVDNAAMQLILKPSQFDVILTTNMFGDILSDE 260 Query: 313 LAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTE 371 AA G +G+ P A+ GD+ L+E G+AP AG++ NP + ILS MML H G E Sbjct: 261 SAALPGSLGLLPSASFGDKN-LYEPAGGSAPDIAGKNIANPIAQILSLAMMLEHSFGMVE 319 Query: 372 AADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 A I + +E I T D D K + S+ GD I + + Sbjct: 320 EARKIERAVELVIEEGYRTRDIAE--DPEKAVSTSQMGDLICKKL 362 >1A05-A nrPDB Length = 358 Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 99/354 (27%), Positives = 153/354 (43%), Gaps = 68/354 (19%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I GDGIG ++ A +V+DA + A+ G R E G + D LPA + Sbjct: 4 IAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLR---CTEGLVG--GAALDASDDPLPAAS 58 Query: 89 LDLIREYRVAIKG-----------PLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGT 137 L L I G P P G +R LR+ LDLY LRP + + Sbjct: 59 LQLAMAADAVILGAVGGPRWDAYPPAKRPEQGLLR-----LRKGLDLYANLRPAQIFPQL 113 Query: 138 --PSPVKHPELT---DMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPE 192 SP++ PEL D+++ RE + DIY G + D ++ Sbjct: 114 LDASPLR-PELVRDVDILVVRELTGDIYFGQPRGLEVIDGKR------------------ 154 Query: 193 HCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 G E+ +R+ A A R + V K N+++ T +++ ++AR+ Sbjct: 155 -RGFNTMVYDEDEIRRIAHVAFRAAQGR-RKQLCSVDKANVLETTR-LWREVVTEVARDY 211 Query: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 ++ + + D Q++ PA++DV+ N+ GD +SD Sbjct: 212 --------------------PDVRLSHMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDE 251 Query: 313 LAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH 366 + G IG+ P A++G+ A++E HG+AP AGQDK NP + ILS MMLRH Sbjct: 252 ASQLTGSIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATILSVAMMLRH 305 >5GRH-B nrPDB Length = 354 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 99/360 (27%), Positives = 162/360 (45%), Gaps = 62/360 (17%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDGIG P ++ V + A + + E++ + + +D+ Sbjct: 18 VTMIPGDGIG----PELMLHVKSVFRHACV---PVDFEEVHVSSNADE---EDIR---NA 64 Query: 89 LDLIREYRVAIKGPLTTP--VGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPEL 146 + IR RVA+KG + T + +S N LR LDLY V + + P V + Sbjct: 65 IMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYA---NVIHCKSLPGVVTRHKD 121 Query: 147 TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGT 206 D++I REN+E Y+ +E ++ + V++ L+ K +R E+ K E G Sbjct: 122 IDILIVRENTEGEYSSLEHESVAG----VVESLKIITKAKSLRIAEY---AFKLAQESGR 174 Query: 207 KRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKV 266 K+ VT VHK NIMK +G F Q RE + Sbjct: 175 KK----------------VTAVHKANIMKLGDGLF----LQCCRE------------VAA 202 Query: 267 KNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGA 326 + P +I +++I D Q++ RP ++DV+ NL G+ +++ A VGG G+ GA Sbjct: 203 RYP----QITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGA 258 Query: 327 NIGDECALFE-ATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAIN 385 N G A+FE AT T A ++ NP + +L++ MML H+ A I K + +++ Sbjct: 259 NYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMD 318 >3U1H-A nrPDB Length = 390 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 109/396 (27%), Positives = 177/396 (44%), Gaps = 61/396 (15%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG +V A ++V+ A E+ + E + + I G + G LP ET Sbjct: 26 IAVLPGDGIGPEVMEAAIEVLKAVAER-FGHEFEFEYGLI--GGAAIDEAGTP--LPEET 80 Query: 89 LDLIREYRV----AIKGPLTTPVGGGIRSLN--VALRQELDLYICLRPVRYYQ--GTPSP 140 LD+ R A+ GP +R + +R+ LDL+ LRPV+ Y SP Sbjct: 81 LDVCRGSDAILLGAVGGPKWDQNPSELRPEKGLLGIRKGLDLFANLRPVKVYDSLADASP 140 Query: 141 VKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 +K E D+VI RE + +Y G + R E G E + Sbjct: 141 LKKEVIEGVDLVIVRELTGGLYFGEPSE-------------RYEEG-------EEAAVDT 180 Query: 199 KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI 258 + E +R++R A E A+ + VT V K N+++ + +++ ++A+E Sbjct: 181 LLYTREEIERIIRKAFELALTRKK-KVTSVDKANVLESSR-LWREVAEEVAKEY------ 232 Query: 259 DGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVG 318 ++ ++ ++ D Q++ P ++DVI N+ GD +SD + G Sbjct: 233 --------------PDVELEHMLVDNAAMQLIRNPRQFDVIVTENMFGDILSDEASMITG 278 Query: 319 GIGIAPGANIG-DECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADLI 376 +G+ P A++ D L+E HG+AP AG+ NP + ILSA MMLR+ G E A I Sbjct: 279 SLGMLPSASLSTDGLGLYEPVHGSAPDIAGKGIANPLATILSAAMMLRYSFGLEEEAKAI 338 Query: 377 VKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAI 412 K +E + T D + G K + +E D + Sbjct: 339 EKAVEKVLAEGYRTADIAK--PGGKYVSTTEMTDEV 372 >3FMX-X nrPDB Length = 364 Score = 100 bits (250), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 101/380 (26%), Positives = 166/380 (43%), Gaps = 61/380 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGE-KSTQVYGQD-VWLPA 86 I I GDGIG++V P ++V++AA K +E T E S Y Q +P Sbjct: 8 IAAIPGDGIGLEVLPEGIRVLEAAALKHGLA------LEFDTFEWASCDYYLQHGKMMPD 61 Query: 87 ETLDLIREYRV----AIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVK 142 + + +++Y A+ P P + + R+E D Y+ +RPVR + G P + Sbjct: 62 DWAEQLKQYDAIYFGAVGWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALA 121 Query: 143 HPEL--TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKP 200 + ++ D V+ REN+E Y+ + + + E+ +++ F Sbjct: 122 NRKVGDIDFVVVRENTEGEYSSL--------GGIMFENTENEIVIQESIF---------- 163 Query: 201 CSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDG 260 + G R+++ A + A +R VT K N M + Y R E Sbjct: 164 -TRRGVDRILKYAFDLAEKRERKHVTSATKSNGMAISMP------YWDKRTEA------- 209 Query: 261 GPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGI 320 + P+ + D++ F+ L+P +DV+ NL GD +SD A G I Sbjct: 210 ---MAAHYPHVSWDKQHIDILCARFV----LQPERFDVVVASNLFGDILSDLGPACAGTI 262 Query: 321 GIAPGANIGDE---CALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMG-----WTEA 372 GIAP AN+ E +LFE HG+AP G++ NP ++I S +ML +G + A Sbjct: 263 GIAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPIAMIWSGALMLEFLGQGDERYQRA 322 Query: 373 ADLIVKGMEGAINAKTVTYD 392 D ++ +E I +VT D Sbjct: 323 HDDMLNAIERVIADGSVTPD 342 >1XAD-A nrPDB Length = 345 Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 99/356 (27%), Positives = 155/356 (43%), Gaps = 61/356 (17%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + + GDGIG +VT A LKV+ A E G +++ G + +G+ P T Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLG---LAYEVFPFGGAAIDAFGEP--FPEPT 57 Query: 89 LDLIREYRVAIKGPLTTPV-GGGIRSLN-----VALRQELDLYICLRPVRYYQGTP--SP 140 + E + G + P R L +++R++LDL+ LRPV+ ++ SP Sbjct: 58 RKGVEEAEAVLLGSVGGPKWDQNPRELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASP 117 Query: 141 VKHPEL--TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 +K + D VI RE + IY G A+A ++ + E+ Sbjct: 118 LKKEYIDNVDFVIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEV--------------- 162 Query: 199 KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI 258 +R+ R A E A R V V K N+++ G F ++ EE G Sbjct: 163 --------ERVARVAFE-AARKRRKHVVSVDKANVLEV--GEF----WRKTVEEVG---- 203 Query: 259 DGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVG 318 G P ++ ++ DA ++ PA +DV+ N+ GD +SD + G Sbjct: 204 RGYP-----------DVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPG 252 Query: 319 GIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAA 373 +G+ P A++G +FE HG+AP AG+ NP + ILSA MML H G E A Sbjct: 253 SLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEHAFGLVELA 308 >1IDM-A nrPDB Length = 343 Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 95/346 (27%), Positives = 150/346 (43%), Gaps = 58/346 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + + GDGIG +VT A LKV+ A E G +++ G + +G+ P T Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLG---LAYEVFPFGGAAIDAFGEP--FPEPT 57 Query: 89 LDLIREYRVAIKGPLTTPV--GGGIRSLN--VALRQELDLYICLRPVRYYQGTP--SPVK 142 + E + G + P G +R ++LR+ DL+ LRP + + G SP+K Sbjct: 58 RKGVEEAEAVLLGSVGGPKWGTGSVRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLK 117 Query: 143 H--PELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKP 200 D++I RE + IY G A+A ++ + E+ Sbjct: 118 EEIARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEV----------------- 160 Query: 201 CSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDG 260 +R+ R A E A R V V K N+++ G F ++ EE G G Sbjct: 161 ------ERVARVAFE-AARKRRKHVVSVDKANVLEV--GEF----WRKTVEEVG----RG 203 Query: 261 GPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGI 320 P ++ ++ DA ++ PA +DV+ N+ GD +SD + G + Sbjct: 204 YP-----------DVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 252 Query: 321 GIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH 366 G+ P A++G +FE HG+AP AG+ NP + ILSA MML H Sbjct: 253 GLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEH 298 >1V5B-A nrPDB Length = 366 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 97/402 (24%), Positives = 168/402 (41%), Gaps = 65/402 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + + GDGIG +V A ++V+ ++ G + + G + LP ET Sbjct: 5 LAVLPGDGIGPEVMDAAIRVLKTVLDN--DGHEAVFENALIGGAAIDEA---GTPLPEET 59 Query: 89 LDLIREYRV----AIKGPLTTPVGGGIRSLN--VALRQELDLYICLRPVRYYQG--TPSP 140 LD+ R A+ GP +R + LR+E+ L+ LRPV+ Y SP Sbjct: 60 LDICRRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASP 119 Query: 141 VKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 +K E D+VI RE + +Y G + +V+ L Sbjct: 120 LKRERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDTL------------------- 160 Query: 199 KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI 258 + E +R++ A + A R + V K N+++ + Sbjct: 161 -AYTREEIERIIEKAFQLAQIR-RKKLASVDKANVLESSR-------------------- 198 Query: 259 DGGPWLKVKNPNTGK--EIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQ 316 W ++ K ++ + ++ D+ Q++ P ++DVI N+ GD +SD + Sbjct: 199 ---MWREIAEETAKKYPDVELSHMLVDSTAMQLIANPGQFDVIVTENMFGDILSDLASVI 255 Query: 317 VGGIGIAPGANI-GDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAAD 374 G +G+ P A++ D ++E HG+AP AGQ K NP +LSA +MLR+ G + A Sbjct: 256 TGSLGMLPSASLRSDRFGMYEPVHGSAPDIAGQGKANPLGTVLSAALMLRYSFGLEKEAA 315 Query: 375 LIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 I K ++ + T D + + K++ E D +IE + Sbjct: 316 AIEKAVDDVLQDGYCTGDLQ--VANGKVVSTIELTDRLIEKL 355 >5J32-A nrPDB Length = 403 Score = 89.0 bits (219), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 102/406 (25%), Positives = 172/406 (42%), Gaps = 71/406 (17%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGER-KISWMEIYTGEKSTQVYGQDVWLPAE 87 I + GDGIG P ++ + +++A E + ++ E+ G + + G V LP E Sbjct: 43 ITLLPGDGIG----PEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVG--VPLPEE 96 Query: 88 TLDLIREYRVAIKGPLTTPVGGGIRSLN-----------VALRQELDLYICLRPV----R 132 T+ +E + G + GG + N + +R L ++ LRP + Sbjct: 97 TISAAKESDAVLLGAI-----GGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQ 151 Query: 133 YYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPE 192 + + E D+++ RE + IY G E G+K E Sbjct: 152 LVDASTLKREVAEGVDLMVVRELTGGIYFG------------------EPRGIKTNENGE 193 Query: 193 HCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 G + + R+ R A E A R + V K N+++ A W ++ Sbjct: 194 EVGFNTEVYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLE----ASILWRKRVT--- 245 Query: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 L + P+ + + + D Q++ P ++D I N+ GD +SD Sbjct: 246 ----------ALASEYPD----VELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDE 291 Query: 313 LAAQVGGIGIAPGANIGDEC-ALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWT 370 + G IG+ P A++ D LFE HG+AP AGQDK NP + ILSA M+L++ +G Sbjct: 292 ASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEE 351 Query: 371 EAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 +AA I + A+N T D G KL+ C E G+ +++++ Sbjct: 352 KAAKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVLKSV 395 >3VMJ-A nrPDB Length = 375 Score = 84.3 bits (207), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 102/380 (26%), Positives = 159/380 (41%), Gaps = 68/380 (17%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG +V KV+ A VE + I + E G + +G LP T Sbjct: 16 IAVLAGDGIGPEVMAEARKVLKA-VEARFG--LNIEYTEYDVGGIAIDNHG--CPLPEAT 70 Query: 89 LDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGTP--S 139 L + G + P + R + LR +L+ LRP + + G S Sbjct: 71 LKGCEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMS 130 Query: 140 PVKH---PELTDMVIFRENSEDIY----AGIEWKADSADAEKVIKFLREEMGVKKIRFPE 192 P++ D++ RE + IY G + + +S +A +++ R E+ Sbjct: 131 PLRSDISARGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRREI--------- 181 Query: 193 HCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 R+ R A E A R VT V K N++ A Q+ E Sbjct: 182 --------------SRIARIAFEAARGR-RKKVTSVDKANVL-----ACSVLWRQVVEE- 220 Query: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 + V P+ + ++ + D Q+L RP E+DV+ C NL GD +SD Sbjct: 221 -----------VAVDFPD----VELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDE 265 Query: 313 LAAQVGGIGIAPGANIGDE-CALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWT 370 +A G +G+ A++ LFE G+AP AG+ NP + ILSA +MLRH + Sbjct: 266 IAMLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQILSAALMLRHSLKQE 325 Query: 371 EAADLIVKGMEGAINAKTVT 390 EAA I + + A+N+ +T Sbjct: 326 EAASAIERAVTKALNSGYLT 345 >4IWH-A nrPDB Length = 363 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 102/398 (25%), Positives = 170/398 (42%), Gaps = 61/398 (15%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG ++ +KV++A EK G + G LP T Sbjct: 11 IAVLPGDGIGPEIVNEAVKVLNALDEK-------FELEHAPVGGAGYEASGHP--LPDAT 61 Query: 89 LDLIREYRVAIKGPLTTPVGGGI-RSLN-----VALRQELDLYICLRPVRYYQGT--PSP 140 L L +E + G + + R+L + LR+ L+L+ RP Y SP Sbjct: 62 LALAKEADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASP 121 Query: 141 VKHPELT---DMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIG 197 +K PEL D++I RE + DIY G + A F E G +R+ Sbjct: 122 LK-PELVAGLDILIVRELNGDIYFG---QPRGVRAAPDGPFAGEREGFDTMRY------- 170 Query: 198 IKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGEL 257 SE +R+ A + A + ++ V K N+++ T ++D +++E Sbjct: 171 ----SEPEVRRIAHVAFQAAQKRAKKLLS-VDKSNVLE-TSQFWRDVMIDVSKEY----- 219 Query: 258 IDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQV 317 ++ + + D Q+ P ++DVI N+ GD +SD + Sbjct: 220 ---------------ADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLT 264 Query: 318 GGIGIAPGANIG-DECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADL 375 G IG+ P A++ + L+E +HG+AP AG+ NP + ILSA M+LR+ + E AD Sbjct: 265 GSIGMLPSASLDKNNKGLYEPSHGSAPDIAGKGIANPLATILSAAMLLRYSLNRAEQADR 324 Query: 376 IVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAII 413 I + ++ + T D G + + + GDA++ Sbjct: 325 IERAVKTVLEQGYRTGDIA--TPGCRQVGTAAMGDAVV 360 >1CNZ-A nrPDB Length = 363 Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 100/410 (24%), Positives = 171/410 (41%), Gaps = 75/410 (18%) Query: 23 VPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDV 82 + +N I + GDGIG +V LKV+DA + + +I+ G + +G Sbjct: 1 MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRF---DMRITTSHYDVGGIAIDNHGHP- 56 Query: 83 WLPAETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQ 135 LP T++ + + G + P + R + LR+ L+ LRP + YQ Sbjct: 57 -LPKATVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQ 115 Query: 136 GTPS--PVKH---PELTDMVIFRENSEDIYAGI-EWKADSADAEKVIK---FLREEMGVK 186 G + P++ D++ RE + IY G + + S EK + R E+ Sbjct: 116 GLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEI--- 172 Query: 187 KIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGY 246 +R+ R A E A R VT + K N+++ + Sbjct: 173 --------------------ERIARIAFESA-RKRRRKVTSIDKANVLQSSI-------- 203 Query: 247 QLAREEFGGELIDGGPWLKVKN--PNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNL 304 W ++ N T ++ + + D Q++ P+++DV+ C NL Sbjct: 204 ---------------LWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNL 248 Query: 305 NGDYISDALAAQVGGIGIAPGANIGDE-CALFEATHGTAPKYAGQDKVNPGSIILSAEMM 363 GD +SD A G +G+ P A++ ++ L+E G+AP AG++ NP + ILS ++ Sbjct: 249 FGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALL 308 Query: 364 LRH-MGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAI 412 LR+ + +AA I + + A+ T D R GA + E GD I Sbjct: 309 LRYSLDANDAATAIEQAINRALEEGVRTGDLAR---GAAAVSTDEMGDII 355 >3VMK-A nrPDB Length = 375 Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 98/404 (24%), Positives = 172/404 (42%), Gaps = 68/404 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG +V KV+ AAVEK + + I + E G + +G LP T Sbjct: 16 IAVLAGDGIGPEVMAEARKVL-AAVEKRF--DLSIEYSEYDVGGAAIDNHG--CPLPEAT 70 Query: 89 LDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGTP--S 139 L + G + P + R + LR +L+ +RP + + G S Sbjct: 71 LKGCEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMS 130 Query: 140 PVKH---PELTDMVIFRENSEDIY----AGIEWKADSADAEKVIKFLREEMGVKKIRFPE 192 P++ + D++ RE + IY G + + ++ +A +++ R+E+ Sbjct: 131 PLRSDISEKGFDILCVRELTGGIYFGKPKGRQGEGENEEAFDTMRYSRKEI--------- 181 Query: 193 HCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 +R+ + A E A R VT V K N++ + ++ EE Sbjct: 182 --------------RRIAKIAFESAQGR-RKKVTSVDKANVLACS------VLWREVVEE 220 Query: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 + D + ++ + D Q+L RP E+DV+ C NL GD +SD Sbjct: 221 VAKDYPD---------------VELEHIYIDNATMQLLRRPNEFDVMLCSNLFGDIVSDE 265 Query: 313 LAAQVGGIGIAPGANIGDE-CALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWT 370 +A G +G+ ++ + ++E G+AP AGQ NP + ILSA ++LRH + Sbjct: 266 IAMLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQILSAALLLRHSLKLE 325 Query: 371 EAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 +AA I + A++ +T + + ++ S+ GD I + Sbjct: 326 DAALAIEAAVSKALSDGYLTCELLPASERSQAKSTSQMGDYIAQ 369 >1CM7-A nrPDB Length = 363 Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 101/406 (24%), Positives = 170/406 (41%), Gaps = 71/406 (17%) Query: 25 ENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWL 84 +N I + GDGIG +V LKV+DA + +I+ G + +GQ L Sbjct: 3 KNYHIAVLPGDGIGPEVMTQALKVLDAVRNRF---AMRITTSHYDVGGAAIDNHGQP--L 57 Query: 85 PAETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGT 137 P T++ + + G + P + R + LR+ L+ LRP + YQG Sbjct: 58 PPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGL 117 Query: 138 PS--PVKH---PELTDMVIFRENSEDIYAGI-EWKADSADAEKVIK---FLREEMGVKKI 188 + P++ D++ RE + IY G + + S EK + R E+ Sbjct: 118 EAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEI----- 172 Query: 189 RFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQL 248 +R+ R A E A R VT + K N+++ + + Sbjct: 173 ------------------ERIARIAFESA-RKRRHKVTSIDKANVLQSS----------I 203 Query: 249 AREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDY 308 E E+ P ++ + + D Q++ P+++DV+ C NL GD Sbjct: 204 LWREIVNEIATEYP-----------DVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDI 252 Query: 309 ISDALAAQVGGIGIAPGANIGDE-CALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH- 366 +SD A G +G+ P A++ ++ L+E G+AP AG++ NP + ILS ++LR+ Sbjct: 253 LSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYS 312 Query: 367 MGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAI 412 + +AA I + + A+ T D R GA + E GD I Sbjct: 313 LDADDAACAIERAINRALEEGIRTGDLAR---GAAAVSTDEMGDII 355 >3VML-A nrPDB Length = 375 Score = 75.5 bits (184), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 93/380 (24%), Positives = 160/380 (42%), Gaps = 68/380 (17%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG +V KV+ A VE + I + E G + +G LP T Sbjct: 16 IAVLAGDGIGPEVMAEARKVLKA-VEARFG--LNIEYTEYDVGGIAIDNHG--CPLPEAT 70 Query: 89 LDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGTP--S 139 L + G + P + R + LR +L+ +RP + + G S Sbjct: 71 LKGCEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMS 130 Query: 140 PVKH---PELTDMVIFRENSEDIY----AGIEWKADSADAEKVIKFLREEMGVKKIRFPE 192 P++ + D++ RE + IY G + + ++ +A +++ R+E+ Sbjct: 131 PLRSDISEKGFDILCVRELTGGIYFGKPKGRQGEGENEEAFDTMRYSRKEI--------- 181 Query: 193 HCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 +R+ + A E A R VT V K N++ + ++ EE Sbjct: 182 --------------RRIAKIAFESA-QGRRKKVTSVDKANVLACS------VLWREVVEE 220 Query: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 + D + ++ + D Q+L RP E+DV+ C NL GD +SD Sbjct: 221 VAKDYPD---------------VELEHIYIDNATMQLLRRPNEFDVMLCSNLFGDIVSDE 265 Query: 313 LAAQVGGIGIAPGANIGDE-CALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWT 370 +A G +G+ ++ + ++E G+AP AGQ NP + ILSA ++LRH + Sbjct: 266 IAMLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQILSAALLLRHSLKLE 325 Query: 371 EAADLIVKGMEGAINAKTVT 390 +AA I + A+N+ +T Sbjct: 326 DAALAIEAAVSKALNSGYLT 345 >3UDO-A nrPDB Length = 361 Score = 71.2 bits (173), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 100/399 (25%), Positives = 171/399 (42%), Gaps = 67/399 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + + GDGIG V LK++ +K Y +++ +I G S YG V L ET Sbjct: 9 VAVLAGDGIGPLVMKEALKILTFIAQK-YNFSFELNEAKI--GGASIDAYG--VALSDET 63 Query: 89 LDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGT--PS 139 L L + + G + P + R+ + LR+ +L+ LRP + Y+ S Sbjct: 64 LKLCEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHAS 123 Query: 140 PVKHPEL---TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGI 196 P+K+ + D++ RE + IY G ++++G + Sbjct: 124 PLKNEIIQKGVDILCVRELTGGIYFG-----------------KQDLG-------KESAY 159 Query: 197 GIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGE 256 + +++ +R+ R A E A + V L+ K N++ + L RE Sbjct: 160 DTEIYTKKEIERIARIAFESARIRKK-KVHLIDKANVLASS---------ILWREVVANV 209 Query: 257 LIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQ 316 D ++I ++ + D QI+ P+ +DV+ C NL GD +SD LAA Sbjct: 210 AKDY------------QDINLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAI 257 Query: 317 VGGIGIAPGANIGDE-CALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADL 375 G +G+ A++ D+ L+E G+AP A + NP + ILSA +ML++ E A Sbjct: 258 NGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNIANPIAQILSAALMLKYSFKEEQA-- 315 Query: 376 IVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 + +E AI+ + ++ L E GD I+E Sbjct: 316 -AQDIENAISLALAQGKMTKDLNAKSYLNTDEMGDCILE 353 >1ZOR-A nrPDB Length = 399 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 84/356 (23%), Positives = 143/356 (40%), Gaps = 45/356 (12%) Query: 87 ETLDLIREYRVAIKGPLTTP---------VGGGIRSLNVALRQELDLYICLRPVRYYQGT 137 E I++Y V +K TP + +S N +R LD + +P+ + Sbjct: 59 EAAKAIKKYGVGVKCATITPDAERVKEYNLKKAWKSPNATIRAYLDGTVFRKPI-MVKNV 117 Query: 138 PSPVKHPELTDMVIFRENSEDIYAGIEWKADS-ADAEKVIKFLREEMGVKKIRFPEHCGI 196 P VK + ++I R DIY +E K + A+ E V++ +E + +F + + Sbjct: 118 PPLVKRWK-KPIIIGRHAYGDIYNAVEAKVEGPAEVELVVRN-KENKTLLVHKFEGNGVV 175 Query: 197 GIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGE 256 E+ + ++ I YAI+ D + K I K FKD +Q ++ E Sbjct: 176 MAMHNLEKSIRSFAQSCINYAISEKVD-IWFATKDTISKVYHAYFKDI-FQEEVDKRKEE 233 Query: 257 LIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQ 316 L G + ++I D A +LR + ACMN GD +SD +A+ Sbjct: 234 LEKAGV--------NYRYMLIDDAAAQ------ILRSEGGMLWACMNYEGDIMSDMIASG 279 Query: 317 VGGIGIAPGANIG-DECALFEATHGTAPKY------AGQDKVNPGSIILSAEMMLRHMG- 368 G +G+ + D FEA HGT ++ + NP + I + +R G Sbjct: 280 FGSLGLMTSVLVSPDGVYEFEAAHGTVRRHYYRYLKGEKTSTNPTASIFAWTGAIRKRGE 339 Query: 369 ------WTEAADLIVKGMEGAINAKTVTYDFERLMDGA--KLLKCSEFGDAIIENM 416 E AD + K + I + +T D + + K + EF D + +N+ Sbjct: 340 LDGTPEVCEFADKLEKAVINTIESGVITKDLQPFTEPPIDKYVTLEEFIDEVKKNL 395 >5I96-A nrPDB Length = 458 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 28/232 (12%) Query: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKK---IRFPEH-CGIGIKPCSEE 204 + I R D Y ++ AD A K++ ++ GVK+ FP G+G+ ++E Sbjct: 168 ITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYN-TDE 226 Query: 205 GTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWL 264 + +YAI + + + K I+K +G FKD ++ + + + W Sbjct: 227 SISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWY 285 Query: 265 KVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAP 324 + + +I D++A Q+L + V AC N +GD SD LA G +G+ Sbjct: 286 EHR--------LIDDMVA-----QVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMT 331 Query: 325 GANIGDECALF--EATHGTAPKYAGQDK------VNPGSIILSAEMMLRHMG 368 + + EA HGT ++ + + NP + I + L H G Sbjct: 332 SVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRG 383 >4HCX-A nrPDB Length = 409 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 59/246 (23%), Positives = 99/246 (40%), Gaps = 32/246 (13%) Query: 188 IRFPEHCGIGIKPCS-EEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGY 246 + PE G+ + + +E + RA+ Y + N + V L K I+K +G FKD Sbjct: 173 VSIPEDGGVVLGMYNFKESIRDFARASFSYGL-NAKWPVYLSTKNTILKAYDGMFKDEFE 231 Query: 247 QLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNG 306 ++ EEF + G T + +I D++A L+ V AC N +G Sbjct: 232 RVYEEEFKAQFEAAGL--------TYEHRLIDDMVA------ACLKWEGGYVWACKNYDG 277 Query: 307 DYISDALAAQVGGIGIAPGANIGDECALF--EATHGTAPKYAGQ------DKVNPGSIIL 358 D SD +A G +G+ + + EA HGT ++ Q NP + I Sbjct: 278 DVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIF 337 Query: 359 SAEMMLRHMGWTEAADLIVKGME-------GAINAKTVTYDFERLMDGAK-LLKCSEFGD 410 + L+H G + ++ + + +T D L+ + L EF D Sbjct: 338 AWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLD 397 Query: 411 AIIENM 416 AI +N+ Sbjct: 398 AIADNL 403 >4AOY-A nrPDB Length = 402 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 61/273 (22%), Positives = 107/273 (39%), Gaps = 43/273 (15%) Query: 92 IREYRVAIKGPLTTPVGGGIRSLNV---------ALRQELDLYICLRPVR------YYQG 136 I++Y V +K TP + N+ +R LD + P+ + +G Sbjct: 64 IQKYGVGVKCATITPNAQRVEEYNLKKMWKSPNGTIRAILDGTVFRAPIVVNSIKPFVKG 123 Query: 137 TPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGI 196 P+ I R D+Y +E+ SA +++ F E V + E G Sbjct: 124 WKKPIS--------IARHAYGDVYKNVEYYVPSAGKAELV-FTSENGEVSRQTIHEFDGP 174 Query: 197 GI---KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEF 253 G+ +++ + RA YA+ ++D + K I K + FKD ++ E+ Sbjct: 175 GVIMGMHNTDKSIRSFARACFNYALDMNQD-LWFSTKDTISKTYDHRFKDIFQEIYENEY 233 Query: 254 GGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDAL 313 + + KN + I D +A ++R V AC N +GD +SD + Sbjct: 234 KEKF-------EAKNLQYFYTL-IDDAVAR------IIRSEGGMVWACKNYDGDVMSDMV 279 Query: 314 AAQVGGIGIAPGANIG-DECALFEATHGTAPKY 345 A+ G + + + D FEA HGT ++ Sbjct: 280 ASAFGSLAMMTSVLVSPDGKYEFEAAHGTVTRH 312 >3US8-A nrPDB Length = 427 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 17/150 (11%) Query: 203 EEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGP 262 +E RA+ Y + + V L K I+K +G FKD ++ EEF + Sbjct: 207 DESITEFARASFNYGLQR-KVPVYLSTKNTILKAYDGRFKDIFQKVFDEEFAAQFKAEKL 265 Query: 263 WLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGI 322 W + + +I D++A A L+ + V AC N +GD SD +A G +G+ Sbjct: 266 WYEHR--------LIDDMVASA------LKWSGGYVWACKNYDGDVQSDIVAQGFGSLGL 311 Query: 323 APGANIGDECALF--EATHGTAPKYAGQDK 350 + + EA HGT ++ Q + Sbjct: 312 MTSVLMTPDGKTVEAEAAHGTVTRHYRQHQ 341 >6BL1-B nrPDB Length = 425 Score = 34.3 bits (77), Expect = 0.094, Method: Compositional matrix adjust. Identities = 35/148 (23%), Positives = 63/148 (42%), Gaps = 22/148 (14%) Query: 227 LVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFL 286 L K I+K +G FKD ++ +++ + W + + +I D++A A Sbjct: 209 LSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHR--------LIDDMVAQA-- 258 Query: 287 QQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALF--EATHGTAPK 344 ++ + AC N +GD SD++A G +G+ + + EA HGT + Sbjct: 259 ----MKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTR 314 Query: 345 Y-----AGQD-KVNPGSIILSAEMMLRH 366 + GQ+ NP + I + L H Sbjct: 315 HYRMYQKGQETSTNPIASIFAWTRGLAH 342 >2UXQ-A nrPDB Length = 402 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 300 ACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL-FEATHGTAPKYAGQD------KVN 352 AC N +GD +SD +A+ G + + + +EA HGT ++ Q N Sbjct: 265 ACKNYDGDVMSDMVASAFGSLAMMSSVLVSPYGYFEYEAAHGTVQRHYYQHLKGERTSTN 324 Query: 353 PGSIILSAEMMLRHMG 368 P ++I + LR G Sbjct: 325 PVALIYAWTGALRKRG 340 >2QFY-A nrPDB Length = 427 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 30/146 (20%), Positives = 63/146 (43%), Gaps = 17/146 (11%) Query: 202 SEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGG 261 ++E + ++ + AI + + ++ L K I+K +G FKD ++ ++ + G Sbjct: 201 TDESIEGFAHSSFKLAI-DKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLG 259 Query: 262 PWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIG 321 I + + D + Q++ + ++A N +GD SD +A G +G Sbjct: 260 -------------IHYEHRLIDDMVAQMIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLG 305 Query: 322 IAPGANIGDECALF--EATHGTAPKY 345 + + + F EA HGT ++ Sbjct: 306 LMTSILVTPDGKTFESEAAHGTVTRH 331 >5FIP-A nrPDB Length = 334 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 37/145 (25%), Positives = 55/145 (37%), Gaps = 25/145 (17%) Query: 186 KKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWG 245 K + + H G E G K + IE A+ N G + TE WG Sbjct: 203 KNVMYSAHFYTGSASVWENGNKGHIARNIEKALEN----------GLTVFVTE-----WG 247 Query: 246 YQLAREEFGGELIDGGPWLKVKNPNT----GKEIVIKDVIADAFLQQILLRPAEYDVIAC 301 A + G L + WL+ N N + K+ + AFL L P V A Sbjct: 248 TSEASGDGGPYLNEADEWLEFLNSNNISWVNWSLANKNEASAAFLPTTSLDPGNGKVWAV 307 Query: 302 --MNLNGDYISDALAAQVGGIGIAP 324 ++L+G+Y+ A++ GI P Sbjct: 308 NQLSLSGEYVR----ARIKGIPYKP 328 >4JGT-A nrPDB Length = 299 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 5/54 (9%) Query: 85 PAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRP-VRYYQGT 137 P E L +E +V + PL G G+ + +VA L Y+C +P V Y G+ Sbjct: 236 PEEIRHLFQEKKVDLSKPLVATCGSGVTACHVA----LGAYLCGKPDVPIYDGS 285 >2NVK-X nrPDB Length = 488 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 22/41 (53%) Query: 43 PAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVW 83 P + K V +VEK G+ + + + TGE+S VY +W Sbjct: 243 PFLRKTVPLSVEKQDDGKLLVKYKNVETGEESEDVYDTVLW 283 >5FV0-A nrPDB Length = 517 Score = 28.1 bits (61), Expect = 7.1, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 16/25 (64%) Query: 168 DSADAEKVIKFLREEMGVKKIRFPE 192 D EK IKF++EEM +K RF E Sbjct: 94 DEKKIEKFIKFMKEEMEQRKQRFME 118 >3MT5-A nrPDB Length = 726 Score = 28.1 bits (61), Expect = 8.2, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 208 RLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAF 241 +L+ AIEY AN R+S L++ GN +K EG Sbjct: 223 KLLMIAIEYKSAN-RESRILINPGNHLKIQEGTL 255 >3NAF-A nrPDB Length = 798 Score = 27.7 bits (60), Expect = 8.7, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 208 RLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAF 241 +L+ AIEY AN R+S L++ GN +K EG Sbjct: 273 KLLMIAIEYKSAN-RESRILINPGNHLKIQEGTL 305 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1AI3-A nrPDB 569 e-163 5M2E-A nrPDB 540 e-154 6C0E-A nrPDB 537 e-153 3DMS-A nrPDB 528 e-150 2D4V-A nrPDB 508 e-144 2IV0-A nrPDB 502 e-143 1HQS-A nrPDB 501 e-142 2E5M-A nrPDB 473 e-134 1XGV-A nrPDB 460 e-130 1CM7-A nrPDB 369 e-102 1CNZ-A nrPDB 367 e-102 2D1C-A nrPDB 365 e-101 3VMK-A nrPDB 360 e-100 3VMJ-A nrPDB 357 5e-99 5YVT-A nrPDB 357 5e-99 3VML-A nrPDB 356 8e-99 3U1H-A nrPDB 355 2e-98 1VLC-A nrPDB 341 4e-94 3BLV-B nrPDB 335 1e-92 1V5B-A nrPDB 334 3e-92 3ASJ-A nrPDB 329 1e-90 4IWH-A nrPDB 329 1e-90 1A05-A nrPDB 327 7e-90 5J32-A nrPDB 323 1e-88 3TY3-A nrPDB 321 3e-88 1XAD-A nrPDB 319 1e-87 1IDM-A nrPDB 318 3e-87 1WPW-A nrPDB 313 8e-86 3BLX-A nrPDB 310 1e-84 3UDO-A nrPDB 308 4e-84 4Y1P-A nrPDB 307 8e-84 3FMX-X nrPDB 303 8e-83 5GRH-B nrPDB 292 2e-79 5HN5-A nrPDB 281 3e-76 2G4O-A nrPDB 276 2e-74 1ZOR-A nrPDB 257 6e-69 5I96-A nrPDB 236 1e-62 4AOY-A nrPDB 231 4e-61 4HCX-A nrPDB 228 3e-60 3US8-A nrPDB 222 2e-58 Sequences not found previously or not previously below threshold: 6BL1-B nrPDB 220 9e-58 2QFY-A nrPDB 208 5e-54 2UXQ-A nrPDB 204 4e-53 4JQP-A nrPDB 32 0.55 5I24-A nrPDB 32 0.67 6BYS-B nrPDB 30 2.0 2QCS-B nrPDB 30 2.4 5L22-B nrPDB 29 3.1 6AJJ-A nrPDB 29 3.3 2G3M-A nrPDB 29 4.0 5CWS-E nrPDB 29 5.3 2XV4-S nrPDB 29 5.4 >1AI3-A nrPDB Length = 416 Score = 569 bits (1467), Expect = e-163, Method: Composition-based stats. Identities = 416/416 (100%), Positives = 416/416 (100%) Query: 1 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE 60 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE Sbjct: 1 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE 60 Query: 61 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ 120 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ Sbjct: 61 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ 120 Query: 121 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR 180 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR Sbjct: 121 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR 180 Query: 181 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA 240 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA Sbjct: 181 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA 240 Query: 241 FKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA 300 FKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA Sbjct: 241 FKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA 300 Query: 301 CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA 360 CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA Sbjct: 301 CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA 360 Query: 361 EMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 EMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM Sbjct: 361 EMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 >5M2E-A nrPDB Length = 418 Score = 540 bits (1390), Expect = e-154, Method: Composition-based stats. Identities = 327/414 (78%), Positives = 370/414 (89%), Gaps = 1/414 (0%) Query: 4 KVVVPAQGKKITLQ-NGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERK 62 K+ VPA G KIT+ + L+VP+NPIIP+IEGDGIGVD++P M+KVVDAAVEKAYKGERK Sbjct: 5 KIQVPATGDKITVNADMSLSVPKNPIIPFIEGDGIGVDISPVMIKVVDAAVEKAYKGERK 64 Query: 63 ISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQEL 122 I+WME+Y GEK+TQVY QD WLP ETLD +R+Y V+IKGPLTTPVGGGIRSLNVALRQ+L Sbjct: 65 IAWMEVYAGEKATQVYDQDTWLPQETLDAVRDYVVSIKGPLTTPVGGGIRSLNVALRQQL 124 Query: 123 DLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREE 182 DLY+C RPVR+++G PSPVK P DMVIFRENSEDIYAG+EWKA S +AEKVIKFL EE Sbjct: 125 DLYVCQRPVRWFEGVPSPVKKPGDVDMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEE 184 Query: 183 MGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFK 242 MGVKKIRF E+CGIGIKP S+EGTKRLVR A++YA+ NDR SVTLVHKGNIMKFTEGAFK Sbjct: 185 MGVKKIRFTENCGIGIKPVSQEGTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFK 244 Query: 243 DWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACM 302 DWGY++AR+EFG EL+DGGPW++ KNP TGK +V+KDVIADA LQQILLRPAEYDVIA + Sbjct: 245 DWGYEVARDEFGAELLDGGPWMQFKNPKTGKNVVVKDVIADAMLQQILLRPAEYDVIATL 304 Query: 303 NLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEM 362 NLNGDY+SDALAA+VGGIGIAPGAN+ D A+FEATHGTAPKYAGQDKVNPGS+ILSAEM Sbjct: 305 NLNGDYLSDALAAEVGGIGIAPGANLSDSVAMFEATHGTAPKYAGQDKVNPGSLILSAEM 364 Query: 363 MLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 MLRHMGWTEAADLI+KG GAI AKTVTYDFERLMDGA LL CSEFGDA+I M Sbjct: 365 MLRHMGWTEAADLIIKGTNGAIAAKTVTYDFERLMDGATLLSCSEFGDAMIAKM 418 >6C0E-A nrPDB Length = 419 Score = 537 bits (1382), Expect = e-153, Method: Composition-based stats. Identities = 312/414 (75%), Positives = 365/414 (88%), Gaps = 1/414 (0%) Query: 4 KVVVPAQGKKITLQ-NGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERK 62 K+ VPAQG+ IT+ + L+VP+NPIIP+IEGDGIGVDVTP M++VVDAAV+KAY +RK Sbjct: 6 KIKVPAQGEAITVAADHSLHVPDNPIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRK 65 Query: 63 ISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQEL 122 ISWME+Y GEK+T+VYG D WLP ETLD +++Y V+IKGPLTTPVGGGIRSLNVA+RQ++ Sbjct: 66 ISWMEVYAGEKATKVYGGDQWLPKETLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDM 125 Query: 123 DLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREE 182 DLY+CLRP+RY+ G PSPV+ P TDMVIFRENSEDIYAGIEW+AD+ +A+KVI+FL +E Sbjct: 126 DLYVCLRPIRYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKE 185 Query: 183 MGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFK 242 MGVKKIRFPEHCGIG+KP S EGT RLV+AAI+YAI NDR +VTLVHKGNIMKFTEGAFK Sbjct: 186 MGVKKIRFPEHCGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFK 245 Query: 243 DWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACM 302 DWGYQ+AR+ FG + GGPW++ KNP TGK+I+I DVIADAFLQQILLRP +Y VIA + Sbjct: 246 DWGYQVARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATL 305 Query: 303 NLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEM 362 NLNGDYISDALAAQVGGIGIAPGANI D+ A+FEATHGTAPKYAGQ+KVNPGSIILSAEM Sbjct: 306 NLNGDYISDALAAQVGGIGIAPGANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEM 365 Query: 363 MLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 MLRHMGW EAADLI++GMEGAI AKTVTYDFER M GA L+ S F DA+I++M Sbjct: 366 MLRHMGWYEAADLIIRGMEGAIEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 419 >3DMS-A nrPDB Length = 427 Score = 528 bits (1360), Expect = e-150, Method: Composition-based stats. Identities = 311/414 (75%), Positives = 355/414 (85%), Gaps = 1/414 (0%) Query: 4 KVVVPAQGKKITLQ-NGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERK 62 + VP G KIT+ + LNV + PIIPYIEGDG G D+TP M+KVVDAAVEKAY G++K Sbjct: 13 HIKVPEGGDKITVNKDFSLNVSDQPIIPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKK 72 Query: 63 ISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQEL 122 I WMEIY GEK+T+VYG DVWLP ETL +++EY V+IKGPLTTPVGGGIRSLNVALRQEL Sbjct: 73 IHWMEIYAGEKATKVYGPDVWLPEETLQVLKEYVVSIKGPLTTPVGGGIRSLNVALRQEL 132 Query: 123 DLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREE 182 DLY+CLRP++Y++G PSPV+ PE T+MVIFRENSEDIYAGIEW A+S A+KVIKFL+EE Sbjct: 133 DLYVCLRPIQYFKGVPSPVREPEKTNMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEE 192 Query: 183 MGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFK 242 MGVKKIRFP+ GIGIKP S+EGT+RLVR AI+YAI NDR SVTLVHKGNIMKFTEGAF+ Sbjct: 193 MGVKKIRFPQTSGIGIKPVSKEGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFR 252 Query: 243 DWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACM 302 D GY LA++EFG ELIDGGPW+K KNP TG EIV+KD IADAFLQQILLRPAEYDVIA + Sbjct: 253 DAGYALAQKEFGAELIDGGPWMKFKNPKTGNEIVVKDSIADAFLQQILLRPAEYDVIATL 312 Query: 303 NLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEM 362 NLNGDYISDALAAQVGGIGIAPGAN+ D A+FEATHGTAPKYAG+D VNPGS ILSAEM Sbjct: 313 NLNGDYISDALAAQVGGIGIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSEILSAEM 372 Query: 363 MLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 MLRH+GWTEAAD+I+ ME +I K VTYDF RLM+GA + CS FG +IENM Sbjct: 373 MLRHLGWTEAADVIISAMEKSIKQKRVTYDFARLMEGATQVSCSGFGQVLIENM 426 >2D4V-A nrPDB Length = 429 Score = 508 bits (1307), Expect = e-144, Method: Composition-based stats. Identities = 258/429 (60%), Positives = 312/429 (72%), Gaps = 13/429 (3%) Query: 1 MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGE 60 M + + PA G +TL NG L VP+ PIIP+IEGDGIG DVTPAM VVDAAV K Y G+ Sbjct: 1 MTTHIQKPATGSPLTLLNGVLQVPDQPIIPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQ 60 Query: 61 RKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQ 120 R+I+WME++ G+K+ Q+YG+ +LP ET+ IREY+VAIKGPL TPVGGGIRSLNVA+RQ Sbjct: 61 RQIAWMELFAGQKAVQLYGEGQYLPDETMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQ 120 Query: 121 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR 180 +LDLY+CLRPVRY++GTPSP++HPE DMVIFRENSEDIYAGIEW A S +AEK+I+FLR Sbjct: 121 DLDLYVCLRPVRYFEGTPSPMRHPEKVDMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLR 180 Query: 181 EEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA 240 EEMGV KIRFP+ IGIKP S EG++RL+R I+YA+ + + SV+LVHKGNIMKFTEG Sbjct: 181 EEMGVTKIRFPDSSAIGIKPVSTEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGG 240 Query: 241 FKDWGYQLAREEFGGELIDGGPWLKVKNPN-------------TGKEIVIKDVIADAFLQ 287 F+DWGY LA EF G + + +++IKDVIAD FLQ Sbjct: 241 FRDWGYALAEREFAGRVFTWRQKAAISKAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQ 300 Query: 288 QILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAG 347 QILLRP +Y V+A +NLNGDY+SDALAA+VGGIG+APGAN+ D A+FEATHGTAP AG Sbjct: 301 QILLRPEDYSVVATLNLNGDYVSDALAAEVGGIGMAPGANLSDTHAIFEATHGTAPDIAG 360 Query: 348 QDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSE 407 Q K NP S+ILSA MML H+GW EAA IV M I A VT D L L +E Sbjct: 361 QGKANPSSLILSAVMMLEHLGWGEAAQAIVAAMNATIAAGEVTGDLAALRGDVPALSTTE 420 Query: 408 FGDAIIENM 416 F A+I Sbjct: 421 FTAALIRRF 429 >2IV0-A nrPDB Length = 412 Score = 502 bits (1293), Expect = e-143, Method: Composition-based stats. Identities = 234/414 (56%), Positives = 298/414 (71%), Gaps = 10/414 (2%) Query: 4 KVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKI 63 KV P G+KI +NGKL VP+NPIIPY EGDGIG DV PA ++V+DAA +K K ++ Sbjct: 5 KVKPPENGEKIRYENGKLIVPDNPIIPYFEGDGIGKDVVPAAIRVLDAAADKIGK---EV 61 Query: 64 SWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELD 123 W ++Y GE + ++YG +LP +TL+ I+E+RVA+KGPLTTPVGGG RSLNV +RQ LD Sbjct: 62 VWFQVYAGEDAYKLYGN--YLPDDTLNAIKEFRVALKGPLTTPVGGGYRSLNVTIRQVLD 119 Query: 124 LYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEM 183 LY +RPV Y +G PSP+KHPE + VIFREN+ED+YAGIEW S +A K+I+FL+ E Sbjct: 120 LYANVRPVYYLKGVPSPIKHPEKVNFVIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEF 179 Query: 184 GVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKD 243 GV E GIGIKP SE TKRLVR AI YAI N+R SVTLVHKGNIMK+TEGAF+D Sbjct: 180 GVT---IREDSGIGIKPISEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRD 236 Query: 244 WGYQLAREEFGGELIDG-GPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACM 302 WGY++A++EFG I W K +IV+KD IAD QQIL R EYDVIA Sbjct: 237 WGYEVAKQEFGEYCITEDELWDKYGGKQPEGKIVVKDRIADNMFQQILTRTDEYDVIALP 296 Query: 303 NLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEM 362 NLNGDY+SDA AA +GG+GIAPG+NIGD +FE HG+APKYAGQ+KVNP + IL+ + Sbjct: 297 NLNGDYLSDAAAALIGGLGIAPGSNIGDGIGVFEPVHGSAPKYAGQNKVNPTAEILTGAL 356 Query: 363 MLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 M ++GW +A+++I K +E I++ VTYD R M G K + EF +A++EN+ Sbjct: 357 MFEYIGWKDASEMIKKAVEMTISSGIVTYDIHRHMGGTK-VGTREFAEAVVENL 409 >1HQS-A nrPDB Length = 423 Score = 501 bits (1291), Expect = e-142, Method: Composition-based stats. Identities = 281/423 (66%), Positives = 331/423 (78%), Gaps = 17/423 (4%) Query: 9 AQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEI 68 AQG+KIT+ NG LNVP NPIIP+IEGDG G D+ A KV++AAVEKAYKGE+KI+W E+ Sbjct: 2 AQGEKITVSNGVLNVPNNPIIPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEV 61 Query: 69 YTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICL 128 Y GEK+ G+ WLPAETLD+IREY +AIKGPLTTPVGGGIRSLNVALRQELDL++CL Sbjct: 62 YAGEKAYNKTGE--WLPAETLDVIREYFIAIKGPLTTPVGGGIRSLNVALRQELDLFVCL 119 Query: 129 RPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKI 188 RPVRY+ G PSPVK PE TDMVIFREN+EDIYAGIE+ S + +K+I FL+ E+ V KI Sbjct: 120 RPVRYFTGVPSPVKRPEDTDMVIFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNKI 179 Query: 189 RFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQL 248 RFPE GIGIKP SEEGT RLVRAAI+YAI + R SVTLVHKGNIMKFTEGAFK+WGY+L Sbjct: 180 RFPETSGIGIKPVSEEGTSRLVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYEL 239 Query: 249 AREEFGGELIDGGPWLKV-------------KNPNTGKEIVIKDVIADAFLQQILLRPAE 295 A +E+G ++ + ++ +I+IKD IAD FLQQIL RP E Sbjct: 240 AEKEYGDKVFTWAQYDRIAEEQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNE 299 Query: 296 YDVIACMNLNGDYISDALAAQVGGIGIAPGANIGD--ECALFEATHGTAPKYAGQDKVNP 353 +DV+A MNLNGDYISDALAAQVGGIGIAPGANI A+FEATHGTAPKYAG DKVNP Sbjct: 300 FDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDKVNP 359 Query: 354 GSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAII 413 S+ILS ++L H+GW EAADL++K ME I +K VTYDF RLMDGA +KCSEFG+ +I Sbjct: 360 SSVILSGVLLLEHLGWNEAADLVIKSMEKTIASKVVTYDFARLMDGATEVKCSEFGEELI 419 Query: 414 ENM 416 +NM Sbjct: 420 KNM 422 >2E5M-A nrPDB Length = 409 Score = 473 bits (1217), Expect = e-134, Method: Composition-based stats. Identities = 204/411 (49%), Positives = 279/411 (67%), Gaps = 8/411 (1%) Query: 6 VVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISW 65 P G+KI GK VP P+I YIEGDGIG ++T A +KV++ AVE+AY R+I W Sbjct: 4 KEPEDGEKIKFDKGKWIVPNKPVILYIEGDGIGPEITNAAIKVINKAVERAYGSSREIKW 63 Query: 66 MEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLY 125 +E+Y GEK+ ++ P ET +++ +YRV +KGPL TP+G G +S+NVA+R LDLY Sbjct: 64 LEVYAGEKAEKLVND--RFPKETQEMLLKYRVVLKGPLETPIGKGWKSVNVAIRLMLDLY 121 Query: 126 ICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGV 185 +RPV+Y +G SP+KHPE DM+IFREN++D+Y GIE+ +S +A+K+ FLR+E+ Sbjct: 122 ANIRPVKYIEGLESPLKHPEKVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKEL-- 179 Query: 186 KKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWG 245 K+ + GIGIK S+ T+R+ R AI+YAI + R VT++HKGN+MK+TEGAF++W Sbjct: 180 -KVEIEDDTGIGIKVMSKYKTQRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWA 238 Query: 246 YQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLN 305 Y++A +E+ + I + P+ GK I++ D IAD QQI++RP EYD+I N+N Sbjct: 239 YEVALKEYR-DFIVTEEEINQGKPDQGK-IILNDRIADNMFQQIIIRPEEYDIILAPNVN 296 Query: 306 GDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLR 365 GDYISDA A +G IG+ GANIGDE +FEA HGTAPKYAG++ NP II + E+MLR Sbjct: 297 GDYISDAAGALIGNIGMLGGANIGDEGGMFEAIHGTAPKYAGKNVANPTGIIKAGELMLR 356 Query: 366 HMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 MGW EAADLI K + AI K VT D R M G K L E+ D +I+ M Sbjct: 357 WMGWNEAADLIEKAINMAIRDKKVTQDIARFM-GVKALGTKEYADELIKIM 406 >1XGV-A nrPDB Length = 435 Score = 460 bits (1183), Expect = e-130, Method: Composition-based stats. Identities = 197/415 (47%), Positives = 267/415 (64%), Gaps = 8/415 (1%) Query: 2 ESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGER 61 ++ P G + G L VP+NP++ +I GDG+G +V + LKVVDAAV+K Y G R Sbjct: 11 TEELSPPPGGSLVEYSGGSLRVPDNPVVAFIRGDGVGPEVVESALKVVDAAVKKVYGGSR 70 Query: 62 KISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQE 121 +I W E+ G + + G+ LP TL+ IR RVA+KGPL TPVG G RSLNVA+RQ Sbjct: 71 RIVWWELLAGHLAREKCGE--LLPKATLEGIRLARVALKGPLETPVGTGYRSLNVAIRQA 128 Query: 122 LDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLRE 181 LDLY +RPVRYY G P+P K+ + DMVIFREN+ED+YAGIEW DS +A ++ +FL E Sbjct: 129 LDLYANIRPVRYY-GQPAPHKYADRVDMVIFRENTEDVYAGIEWPHDSPEAARIRRFLAE 187 Query: 182 EMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAF 241 E G+ E GIG+KP S T+RL+ A+E+A+ N VT++HKGNIMK+TEGAF Sbjct: 188 EFGIS---IREDAGIGVKPISRFATRRLMERALEWALRNGNTVVTIMHKGNIMKYTEGAF 244 Query: 242 KDWGYQLAREEFGGELIDGGPWLK-VKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIA 300 W Y++A E+F ++ + +I++ D IAD LQQI+ RP +Y VI Sbjct: 245 MRWAYEVALEKFREHVVTEQEVQEKYGGVRPEGKILVNDRIADNMLQQIITRPWDYQVIV 304 Query: 301 CMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSA 360 NLNGDYISDA +A VGGIG+A G N+GD A+ E HGTAPKYAG+D +NP + ILSA Sbjct: 305 APNLNGDYISDAASALVGGIGMAAGMNMGDGIAVAEPVHGTAPKYAGKDLINPSAEILSA 364 Query: 361 EMML-RHMGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 +++ MGW E ++ + A+ +K VT D R M G + L+ SE+ + +I Sbjct: 365 SLLIGEFMGWREVKSIVEYAIRKAVQSKKVTQDLARHMPGVQPLRTSEYTETLIA 419 >1CM7-A nrPDB Length = 363 Score = 369 bits (946), Expect = e-102, Method: Composition-based stats. Identities = 95/406 (23%), Positives = 165/406 (40%), Gaps = 63/406 (15%) Query: 23 VPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDV 82 + +N I + GDGIG +V LKV+DA + +I+ G + +GQ Sbjct: 1 MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRF---AMRITTSHYDVGGAAIDNHGQP- 56 Query: 83 WLPAETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQ 135 LP T++ + + G + P + R + LR+ L+ LRP + YQ Sbjct: 57 -LPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQ 115 Query: 136 GTP--SPVKH---PELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRF 190 G P++ D++ RE + IY G + + Sbjct: 116 GLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQY----------------- 158 Query: 191 PEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAR 250 + +R+ R A E A R VT + K N+++ + +++ ++A Sbjct: 159 --EKAFDTEVYHRFEIERIARIAFESARKR-RHKVTSIDKANVLQSSI-LWREIVNEIAT 214 Query: 251 EEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYIS 310 E ++ + + D Q++ P+++DV+ C NL GD +S Sbjct: 215 EY--------------------PDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILS 254 Query: 311 DALAAQVGGIGIAPGANIGD-ECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MG 368 D A G +G+ P A++ + L+E G+AP AG++ NP + ILS ++LR+ + Sbjct: 255 DECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLD 314 Query: 369 WTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 +AA I + + A+ T D R GA + E GD I Sbjct: 315 ADDAACAIERAINRALEEGIRTGDLAR---GAAAVSTDEMGDIIAR 357 >1CNZ-A nrPDB Length = 363 Score = 367 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 94/406 (23%), Positives = 165/406 (40%), Gaps = 63/406 (15%) Query: 23 VPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDV 82 + +N I + GDGIG +V LKV+DA + + +I+ G + +G Sbjct: 1 MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRF---DMRITTSHYDVGGIAIDNHGHP- 56 Query: 83 WLPAETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQ 135 LP T++ + + G + P + R + LR+ L+ LRP + YQ Sbjct: 57 -LPKATVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQ 115 Query: 136 GTP--SPVKH---PELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRF 190 G P++ D++ RE + IY G + + Sbjct: 116 GLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQY----------------- 158 Query: 191 PEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAR 250 + +R+ R A E A R VT + K N+++ + +++ +A+ Sbjct: 159 --EKAFDTEVYHRFEIERIARIAFESARKRRRK-VTSIDKANVLQSSI-LWREIVNDVAK 214 Query: 251 EEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYIS 310 T ++ + + D Q++ P+++DV+ C NL GD +S Sbjct: 215 --------------------TYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILS 254 Query: 311 DALAAQVGGIGIAPGANIGD-ECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MG 368 D A G +G+ P A++ + L+E G+AP AG++ NP + ILS ++LR+ + Sbjct: 255 DECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLD 314 Query: 369 WTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 +AA I + + A+ T D R GA + E GD I Sbjct: 315 ANDAATAIEQAINRALEEGVRTGDLAR---GAAAVSTDEMGDIIAR 357 >2D1C-A nrPDB Length = 496 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 144/407 (35%), Positives = 212/407 (52%), Gaps = 59/407 (14%) Query: 14 ITLQNGK-LNVPEN--PIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYT 70 IT + GK ++V E+ +I I GDGIG + A LKV++AA + +++ E+ Sbjct: 4 ITTETGKKMHVLEDGRKLITVIPGDGIGPECVEATLKVLEAA-------KAPLAY-EVRE 55 Query: 71 GEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRP 130 S G +P ET++ IR+ RV +KGPL TPVG G +S NV LR+ + Y +RP Sbjct: 56 AGASVFRRGIASGVPQETIESIRKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVRP 115 Query: 131 VRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRF 190 VR + P+P D+V+ REN ED+YAGIE + A+ Sbjct: 116 VREFPNVPTPYAG-RGIDLVVVRENVEDLYAGIEHMQTPSVAQT---------------- 158 Query: 191 PEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAR 250 +K S +G++++VR A E A A R V K NIMK EG K Q+A+ Sbjct: 159 -------LKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVAQ 211 Query: 251 EEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYIS 310 E +I +I D Q++ RP +++VI N+NGD +S Sbjct: 212 EY--------------------PDIEAVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDILS 251 Query: 311 DALAAQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWT 370 D + +GG+G AP ANIG+E A+FEA HG+APKYAG++ +NP +++LSA MMLR++ Sbjct: 252 DLTSGLIGGLGFAPSANIGNEVAIFEAVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEEF 311 Query: 371 EAADLIVKGMEGAINAK-TVTYDFERLMDGAKLLKCSEFGDAIIENM 416 ADLI + + +T D GAK +E+ +AII+N+ Sbjct: 312 ATADLIENALLYTLEEGRVLTGDVVGYDRGAK---TTEYTEAIIQNL 355 >3VMK-A nrPDB Length = 375 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 90/404 (22%), Positives = 161/404 (39%), Gaps = 60/404 (14%) Query: 27 PIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPA 86 I + GDGIG +V KV+ A ++ + I + E G + +G LP Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLAAVEKRF---DLSIEYSEYDVGGAAIDNHG--CPLPE 68 Query: 87 ETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGTP- 138 TL + G + P + R + LR +L+ +RP + + G Sbjct: 69 ATLKGCEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEH 128 Query: 139 -SPVKH---PELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHC 194 SP++ + D++ RE + IY G Sbjct: 129 MSPLRSDISEKGFDILCVRELTGGIYFGKPKGRQGEG-------------------ENEE 169 Query: 195 GIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFG 254 S + +R+ + A E A R VT V K N++ + +++ ++A++ Sbjct: 170 AFDTMRYSRKEIRRIAKIAFESAQGR-RKKVTSVDKANVLACSV-LWREVVEEVAKDY-- 225 Query: 255 GELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALA 314 ++ ++ + D Q+L RP E+DV+ C NL GD +SD +A Sbjct: 226 ------------------PDVELEHIYIDNATMQLLRRPNEFDVMLCSNLFGDIVSDEIA 267 Query: 315 AQVGGIGIAPGANIGD-ECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEA 372 G +G+ ++ ++E G+AP AGQ NP + ILSA ++LRH + +A Sbjct: 268 MLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQILSAALLLRHSLKLEDA 327 Query: 373 ADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 A I + A++ +T + + ++ S+ GD I + + Sbjct: 328 ALAIEAAVSKALSDGYLTCELLPASERSQAKSTSQMGDYIAQAI 371 >3VMJ-A nrPDB Length = 375 Score = 357 bits (916), Expect = 5e-99, Method: Composition-based stats. Identities = 97/402 (24%), Positives = 153/402 (38%), Gaps = 60/402 (14%) Query: 27 PIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPA 86 I + GDGIG +V KV+ A + I + E G + +G LP Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFG---LNIEYTEYDVGGIAIDNHG--CPLPE 68 Query: 87 ETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGTP- 138 TL + G + P + R + LR +L+ LRP + + G Sbjct: 69 ATLKGCEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEH 128 Query: 139 -SPVKH---PELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHC 194 SP++ D++ RE + IY G Sbjct: 129 MSPLRSDISARGFDVLCVRELTGGIYFGKPKGRQGEG-------------------ESEE 169 Query: 195 GIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFG 254 S R+ R A E A R VT V K N++ + ++ ++A + Sbjct: 170 AFDTMRYSRREISRIARIAFEAARGR-RKKVTSVDKANVLACSV-LWRQVVEEVAVD--- 224 Query: 255 GELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALA 314 ++ ++ + D Q+L RP E+DV+ C NL GD +SD +A Sbjct: 225 -----------------FPDVELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIA 267 Query: 315 AQVGGIGIAPGANIGD-ECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEA 372 G +G+ A++ LFE G+AP AG+ NP + ILSA +MLRH + EA Sbjct: 268 MLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQILSAALMLRHSLKQEEA 327 Query: 373 ADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 A I + + A+N+ +T + K + GD I + Sbjct: 328 ASAIERAVTKALNSGYLTGELLSSDQRHKAKTTVQMGDFIAD 369 >5YVT-A nrPDB Length = 339 Score = 357 bits (916), Expect = 5e-99, Method: Composition-based stats. Identities = 120/390 (30%), Positives = 184/390 (47%), Gaps = 63/390 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDGIG +++ A++K+ DAA + I W E + Q G +P+E Sbjct: 7 VTLIPGDGIGPEISAAVMKIFDAA-------KAPIQWEERNV--TAIQGPGGKWMIPSEA 57 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 + + + ++ +KGPL TP+ G S+N+ LR+ DLY +RP +G +P + Sbjct: 58 KESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYT---DVN 114 Query: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKR 208 +V REN+E Y+GIE + IK +E +KR Sbjct: 115 IVTIRENTEGEYSGIEHVIVDGVVQS-----------------------IKLITEGASKR 151 Query: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKN 268 + A EYA N R +VT VHK NIM+ ++G F ++A Sbjct: 152 IAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAE------------------ 193 Query: 269 PNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANI 328 + K+I ++ D ++ P+++DV+ NL GD +SD A +GG+G+ P NI Sbjct: 194 --SCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNI 251 Query: 329 G-DECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAK 387 G + A+FE+ HGTAP AG+D NP +++LSA MMLRHMG + A I I Sbjct: 252 GANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDG 311 Query: 388 T-VTYDFERLMDGAKLLKCSEFGDAIIENM 416 +T D KCS+F + I + Sbjct: 312 KSLTKDL------GGNAKCSDFTEEICRRV 335 >3VML-A nrPDB Length = 375 Score = 356 bits (914), Expect = 8e-99, Method: Composition-based stats. Identities = 91/402 (22%), Positives = 156/402 (38%), Gaps = 60/402 (14%) Query: 27 PIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPA 86 I + GDGIG +V KV+ A + I + E G + +G LP Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFG---LNIEYTEYDVGGIAIDNHG--CPLPE 68 Query: 87 ETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYYQGTP- 138 TL + G + P + R + LR +L+ +RP + + G Sbjct: 69 ATLKGCEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEH 128 Query: 139 -SPVKH---PELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHC 194 SP++ + D++ RE + IY G Sbjct: 129 MSPLRSDISEKGFDILCVRELTGGIYFGKPKGRQGEG-------------------ENEE 169 Query: 195 GIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFG 254 S + +R+ + A E A R VT V K N++ + +++ ++A++ Sbjct: 170 AFDTMRYSRKEIRRIAKIAFESAQGR-RKKVTSVDKANVLACSV-LWREVVEEVAKDY-- 225 Query: 255 GELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALA 314 ++ ++ + D Q+L RP E+DV+ C NL GD +SD +A Sbjct: 226 ------------------PDVELEHIYIDNATMQLLRRPNEFDVMLCSNLFGDIVSDEIA 267 Query: 315 AQVGGIGIAPGANIGD-ECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEA 372 G +G+ ++ ++E G+AP AGQ NP + ILSA ++LRH + +A Sbjct: 268 MLTGSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPVAQILSAALLLRHSLKLEDA 327 Query: 373 ADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 A I + A+N+ +T + K + GD I + Sbjct: 328 ALAIEAAVSKALNSGYLTGELLSSDQRHKAKTTVQMGDFIAD 369 >3U1H-A nrPDB Length = 390 Score = 355 bits (911), Expect = 2e-98, Method: Composition-based stats. Identities = 105/412 (25%), Positives = 174/412 (42%), Gaps = 61/412 (14%) Query: 15 TLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKS 74 T +N I + GDGIG +V A ++V+ A E+ + + G + Sbjct: 12 TTENLYFQGAMKKKIAVLPGDGIGPEVMEAAIEVLKAVAERFG---HEFEFEYGLIGGAA 68 Query: 75 TQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLN------VALRQELDLYICL 128 G LP ETLD+ R + G + P S + +R+ LDL+ L Sbjct: 69 IDEAGTP--LPEETLDVCRGSDAILLGAVGGPKWDQNPSELRPEKGLLGIRKGLDLFANL 126 Query: 129 RPVRYYQGTP--SPVKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMG 184 RPV+ Y SP+K E D+VI RE + +Y G + Sbjct: 127 RPVKVYDSLADASPLKKEVIEGVDLVIVRELTGGLYFGEPSE------------------ 168 Query: 185 VKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDW 244 + E + + E +R++R A E A+ + VT V K N+++ + +++ Sbjct: 169 --RYEEGEEAAVDTLLYTREEIERIIRKAFELALTR-KKKVTSVDKANVLESSR-LWREV 224 Query: 245 GYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNL 304 ++A+E ++ ++ ++ D Q++ P ++DVI N+ Sbjct: 225 AEEVAKEY--------------------PDVELEHMLVDNAAMQLIRNPRQFDVIVTENM 264 Query: 305 NGDYISDALAAQVGGIGIAPGANIG-DECALFEATHGTAPKYAGQDKVNPGSIILSAEMM 363 GD +SD + G +G+ P A++ D L+E HG+AP AG+ NP + ILSA MM Sbjct: 265 FGDILSDEASMITGSLGMLPSASLSTDGLGLYEPVHGSAPDIAGKGIANPLATILSAAMM 324 Query: 364 LRH-MGWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIE 414 LR+ G E A I K +E + T D + G K + +E D + Sbjct: 325 LRYSFGLEEEAKAIEKAVEKVLAEGYRTADIAK--PGGKYVSTTEMTDEVKA 374 >1VLC-A nrPDB Length = 366 Score = 341 bits (874), Expect = 4e-94, Method: Composition-based stats. Identities = 109/401 (27%), Positives = 170/401 (42%), Gaps = 66/401 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG +V LKV++ +K K K+ + G + +G+ LP ET Sbjct: 15 IAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVF---GHIGGDAIDRFGEP--LPEET 69 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSL-------NVALRQELDLYICLRPVRYYQGTP--S 139 + E G + P + +ALR+ L+LY +RP++ Y+ S Sbjct: 70 KKICLEADAIFLGSVGGPKWDDLPPEKRPEIGGLLALRKMLNLYANIRPIKVYRSLVHVS 129 Query: 140 PVKHP---ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGI 196 P+K D+V RE S +Y G D E G Sbjct: 130 PLKEKVIGSGVDLVTVRELSYGVYYGQPRGLD-----------------------EEKGF 166 Query: 197 GIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGE 256 + +R+ R A E A N R VT V K N++ ++ ++ ++ARE Sbjct: 167 DTMIYDRKTVERIARTAFEIA-KNRRKKVTSVDKANVL-YSSMLWRKVVNEVAREY---- 220 Query: 257 LIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQ 316 ++ + + D Q++L+P+++DVI N+ GD +SD AA Sbjct: 221 ----------------PDVELTHIYVDNAAMQLILKPSQFDVILTTNMFGDILSDESAAL 264 Query: 317 VGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADL 375 G +G+ P A+ GD+ L+E G+AP AG++ NP + ILS MML H G E A Sbjct: 265 PGSLGLLPSASFGDKN-LYEPAGGSAPDIAGKNIANPIAQILSLAMMLEHSFGMVEEARK 323 Query: 376 IVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 I + +E I T D D K + S+ GD I + + Sbjct: 324 IERAVELVIEEGYRTRDIAE--DPEKAVSTSQMGDLICKKL 362 >3BLV-B nrPDB Length = 354 Score = 335 bits (860), Expect = 1e-92, Method: Composition-based stats. Identities = 116/396 (29%), Positives = 182/396 (45%), Gaps = 67/396 (16%) Query: 26 NPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLP 85 + +IEGDGIG +++ ++ K+ AA I W S +P Sbjct: 21 KYTVSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESCDV---SPIFVNGLTTIP 70 Query: 86 AETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPE 145 + I + VA+KGPL TP+G G RSLN+ LR+ L+ +RP + +G + E Sbjct: 71 DPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---E 127 Query: 146 LTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEG 205 D+V+ REN+E Y+GIE + IK + + Sbjct: 128 NVDLVLIRENTEGEYSGIEHIVCPGVVQS-----------------------IKLITRDA 164 Query: 206 TKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLK 265 ++R++R A EYA A R V +VHK I + +G F + +L++E Sbjct: 165 SERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEY------------- 211 Query: 266 VKNPNTGKEIVIKDVIADAFLQQILLRPAEYD--VIACMNLNGDYISDALAAQ-VGGIGI 322 ++ ++ + D + +++ P+ Y V C NL GD +SD + G +G+ Sbjct: 212 -------PDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGL 264 Query: 323 APGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEG 382 P ANIG + ++FEA HG+AP AGQDK NP +++LS+ MML HMG T AD I + Sbjct: 265 TPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLS 324 Query: 383 AINAK--TVTYDFERLMDGAKLLKCSEFGDAIIENM 416 I + T D S F +A+I+ + Sbjct: 325 TIASGPENRTGDLA------GTATTSSFTEAVIKRL 354 >1V5B-A nrPDB Length = 366 Score = 334 bits (857), Expect = 3e-92, Method: Composition-based stats. Identities = 95/400 (23%), Positives = 170/400 (42%), Gaps = 61/400 (15%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + + GDGIG +V A ++V+ ++ + G + G LP ET Sbjct: 5 LAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAV---FENALIGGAAIDEAGTP--LPEET 59 Query: 89 LDLIREYRVAIKGPLTTPVG----GGIRSL--NVALRQELDLYICLRPVRYYQGT--PSP 140 LD+ R + G + P +R + LR+E+ L+ LRPV+ Y SP Sbjct: 60 LDICRRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASP 119 Query: 141 VKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 +K E D+VI RE + +Y G + +V+ L Sbjct: 120 LKRERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDTLA------------------ 161 Query: 199 KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI 258 + E +R++ A + A R + V K N+++ + +++ + A++ Sbjct: 162 --YTREEIERIIEKAFQLAQIR-RKKLASVDKANVLESSR-MWREIAEETAKKY------ 211 Query: 259 DGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVG 318 ++ + ++ D+ Q++ P ++DVI N+ GD +SD + G Sbjct: 212 --------------PDVELSHMLVDSTAMQLIANPGQFDVIVTENMFGDILSDLASVITG 257 Query: 319 GIGIAPGANI-GDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADLI 376 +G+ P A++ D ++E HG+AP AGQ K NP +LSA +MLR+ G + A I Sbjct: 258 SLGMLPSASLRSDRFGMYEPVHGSAPDIAGQGKANPLGTVLSAALMLRYSFGLEKEAAAI 317 Query: 377 VKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 K ++ + T D + + K++ E D +IE + Sbjct: 318 EKAVDDVLQDGYCTGDLQ--VANGKVVSTIELTDRLIEKL 355 >3ASJ-A nrPDB Length = 334 Score = 329 bits (844), Expect = 1e-90, Method: Composition-based stats. Identities = 115/392 (29%), Positives = 177/392 (45%), Gaps = 65/392 (16%) Query: 27 PIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPA 86 I IEGDGIG +V PA +V++A + ++E G ++ + G V P Sbjct: 3 YRICLIEGDGIGHEVIPAARRVLEAT-------GLPLEFVEAEAGWETFERRGTSV--PE 53 Query: 87 ETLDLIREYRVAIKGPLTTPVG--GGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHP 144 ET++ I + G T+P G LR+ LDLY +RP + P P P Sbjct: 54 ETVEKILSCHATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAK---SRPVPGSRP 110 Query: 145 ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEE 204 D+VI REN+E +Y E + I S++ Sbjct: 111 -GVDLVIVRENTEGLYVEQERR------------------------YLDVAIADAVISKK 145 Query: 205 GTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWL 264 ++R+ RAA+ A R ++ + HK N++ T+G F D ++A++ Sbjct: 146 ASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQGLFLDTVKEVAKD------------- 192 Query: 265 KVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAP 324 + ++D+I D Q+++RP +DVI NL GD +SD A VGG+G+AP Sbjct: 193 -------FPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGGLGLAP 245 Query: 325 GANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAI 384 NIGD A+FE HG+AP AG+ NP + ILSA MML ++G EAA + K ++ + Sbjct: 246 SGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEKAVDLVL 305 Query: 385 NAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 T D F +A++E + Sbjct: 306 ERGPRTPDL------GGDATTEAFTEAVVEAL 331 >4IWH-A nrPDB Length = 363 Score = 329 bits (843), Expect = 1e-90, Method: Composition-based stats. Identities = 94/400 (23%), Positives = 161/400 (40%), Gaps = 59/400 (14%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I + GDGIG ++ +KV++A EK G + G LP T Sbjct: 11 IAVLPGDGIGPEIVNEAVKVLNALDEK-------FELEHAPVGGAGYEASGHP--LPDAT 61 Query: 89 LDLIREYRVAIKGPLTTPVGGGIR------SLNVALRQELDLYICLRPVRYYQGT--PSP 140 L L +E + G + + + LR+ L+L+ RP Y SP Sbjct: 62 LALAKEADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASP 121 Query: 141 VKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 +K D++I RE + DIY G +A E G Sbjct: 122 LKPELVAGLDILIVRELNGDIYFGQPRGVRAAPDGPFA--------------GEREGFDT 167 Query: 199 KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI 258 SE +R+ A + A + + V K N+++ ++ ++D +++E Sbjct: 168 MRYSEPEVRRIAHVAFQAAQKRAKKLL-SVDKSNVLETSQ-FWRDVMIDVSKEYA----- 220 Query: 259 DGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVG 318 ++ + + D Q+ P ++DVI N+ GD +SD + G Sbjct: 221 ---------------DVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTG 265 Query: 319 GIGIAPGANIG-DECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADLI 376 IG+ P A++ + L+E +HG+AP AG+ NP + ILSA M+LR+ + E AD I Sbjct: 266 SIGMLPSASLDKNNKGLYEPSHGSAPDIAGKGIANPLATILSAAMLLRYSLNRAEQADRI 325 Query: 377 VKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 + ++ + T D G + + + GDA++ + Sbjct: 326 ERAVKTVLEQGYRTGDIA--TPGCRQVGTAAMGDAVVAAL 363 >1A05-A nrPDB Length = 358 Score = 327 bits (837), Expect = 7e-90, Method: Composition-based stats. Identities = 99/399 (24%), Positives = 165/399 (41%), Gaps = 59/399 (14%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 I GDGIG ++ A +V+DA + A+ G R E G + D LPA + Sbjct: 4 IAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLR---CTEGLVGGAALDA--SDDPLPAAS 58 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSL------NVALRQELDLYICLRPVRYYQGT--PSP 140 L L I G + P + LR+ LDLY LRP + + SP Sbjct: 59 LQLAMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASP 118 Query: 141 VKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 ++ D+++ RE + DIY G + D ++ G Sbjct: 119 LRPELVRDVDILVVRELTGDIYFGQPRGLEVIDGKR-------------------RGFNT 159 Query: 199 KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI 258 E+ +R+ A A R + V K N+++ T +++ ++AR+ Sbjct: 160 MVYDEDEIRRIAHVAFRAAQGR-RKQLCSVDKANVLETTR-LWREVVTEVARDY------ 211 Query: 259 DGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVG 318 ++ + + D Q++ PA++DV+ N+ GD +SD + G Sbjct: 212 --------------PDVRLSHMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQLTG 257 Query: 319 GIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADLIV 377 IG+ P A++G+ A++E HG+AP AGQDK NP + ILS MMLRH + A + Sbjct: 258 SIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATILSVAMMLRHSLNAEPWAQRVE 317 Query: 378 KGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 ++ ++ T D G ++ G A++ + Sbjct: 318 AAVQRVLDQGLRTADIAA--PGTPVIGTKAMGAAVVNAL 354 >5J32-A nrPDB Length = 403 Score = 323 bits (827), Expect = 1e-88, Method: Composition-based stats. Identities = 100/404 (24%), Positives = 165/404 (40%), Gaps = 59/404 (14%) Query: 25 ENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWL 84 + I + GDGIG +V V+ A + ++ E+ G + + G V L Sbjct: 39 KRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEG---VEFNFREMPIGGAALDLVG--VPL 93 Query: 85 PAETLDLIREYRVAIKGPLTTPVG----GGIRSL--NVALRQELDLYICLRPVRYYQGT- 137 P ET+ +E + G + +R + +R L ++ LRP Sbjct: 94 PEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLV 153 Query: 138 -PSPVKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHC 194 S +K E D+++ RE + IY G G+K E Sbjct: 154 DASTLKREVAEGVDLMVVRELTGGIYFGEPR------------------GIKTNENGEEV 195 Query: 195 GIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFG 254 G + + R+ R A E A R + V K N+++ + ++ LA E Sbjct: 196 GFNTEVYAAHEIDRIARVAFETARKR-RGKLCSVDKANVLEASI-LWRKRVTALASEY-- 251 Query: 255 GELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALA 314 ++ + + D Q++ P ++D I N+ GD +SD + Sbjct: 252 ------------------PDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEAS 293 Query: 315 AQVGGIGIAPGANIGD-ECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEA 372 G IG+ P A++ D LFE HG+AP AGQDK NP + ILSA M+L++ +G +A Sbjct: 294 MITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATILSAAMLLKYGLGEEKA 353 Query: 373 ADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 A I + A+N T D G KL+ C E G+ +++++ Sbjct: 354 AKRIEDAVLVALNNGFRTGDI--YSAGTKLVGCKEMGEEVLKSV 395 >3TY3-A nrPDB Length = 366 Score = 321 bits (823), Expect = 3e-88, Method: Composition-based stats. Identities = 102/403 (25%), Positives = 184/403 (45%), Gaps = 48/403 (11%) Query: 20 KLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYG 79 ++ ++ I DGIG +V PA ++++ K + K ++++ G + + G Sbjct: 4 SMSATRRIVLGLIPADGIGKEVVPAARRLME---NLPAKHKLKFDFIDLDAGWGTFERTG 60 Query: 80 QDVWLPAETLDLIR-EYRVAIKGPLTTPVGG--GIRSLNVALRQELDLYICLRPVRYYQG 136 + LP T++ ++ E A+ G + +P G S VALR+++ LY +RPV+ G Sbjct: 61 K--ALPERTVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDG 118 Query: 137 TPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGI 196 + D+VI REN+E +Y E + ++V + +R R E Sbjct: 119 AKG-----KPVDLVIVRENTECLYVKEERMVQNTPGKRVAEAIR--------RISEEAST 165 Query: 197 GIKPCSEE--GTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFG 254 I + E +++ +R + Y+I + + VT++HK N+M T+G F++ Sbjct: 166 KIGKMAFEIAKSRQKIRESGTYSI-HKKPLVTIIHKSNVMSVTDGLFRESCRH------- 217 Query: 255 GELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALA 314 + I + + I D+ + ++ P +DV+ NL GD +SD A Sbjct: 218 ----------AQSLDPSYASINVDEQIVDSMVYRLFREPECFDVVVAPNLYGDILSDGAA 267 Query: 315 AQVGGIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAAD 374 + +G +G+ P AN+GD + E HG+AP AG+ NP + S +ML MG +AA Sbjct: 268 SLIGSLGLVPSANVGDNFVMSEPVHGSAPDIAGRGIANPVATFRSVALMLEFMGHQDAAA 327 Query: 375 LIVKGMEGAI-NAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 I ++ + K +T D +E DA++ N+ Sbjct: 328 DIYTAVDKVLTEGKVLTPDL------GGKSGTNEITDAVLANI 364 >1XAD-A nrPDB Length = 345 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 99/399 (24%), Positives = 161/399 (40%), Gaps = 68/399 (17%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + + GDGIG +VT A LKV+ A E G +++ G + +G+ P T Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLG---LAYEVFPFGGAAIDAFGEP--FPEPT 57 Query: 89 LDLIREYRVAIKGPLTTPVG-GGIRSL-----NVALRQELDLYICLRPVRYYQGT--PSP 140 + E + G + P R L +++R++LDL+ LRPV+ ++ SP Sbjct: 58 RKGVEEAEAVLLGSVGGPKWDQNPRELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASP 117 Query: 141 VKHP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 +K + D VI RE + IY G A+A ++ + E Sbjct: 118 LKKEYIDNVDFVIVRELTGGIYFGEPRGMSEAEAWNTERYSKPE---------------- 161 Query: 199 KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELI 258 +R+ R A E A R V V K N+++ E ++ EE G Sbjct: 162 -------VERVARVAFEAARKR-RKHVVSVDKANVLEVGE------FWRKTVEEVG---- 203 Query: 259 DGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVG 318 ++ ++ DA ++ PA +DV+ N+ GD +SD + G Sbjct: 204 -----------RGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPG 252 Query: 319 GIGIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADLIV 377 +G+ P A++G +FE HG+AP AG+ NP + ILSA MML H G E A + Sbjct: 253 SLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEHAFGLVELARKVE 312 Query: 378 KGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 + A+ D F ++ ++ Sbjct: 313 DAVAKALLE-------TPPPDLGGSAGTEAFTATVLRHL 344 >1IDM-A nrPDB Length = 343 Score = 318 bits (815), Expect = 3e-87, Method: Composition-based stats. Identities = 98/397 (24%), Positives = 159/397 (40%), Gaps = 66/397 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + + GDGIG +VT A LKV+ A E G +++ G + +G+ P T Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLG---LAYEVFPFGGAAIDAFGEP--FPEPT 57 Query: 89 LDLIREYRVAIKGPLTTPVGG--GIRSL--NVALRQELDLYICLRPVRYYQGTP--SPVK 142 + E + G + P G +R ++LR+ DL+ LRP + + G SP+K Sbjct: 58 RKGVEEAEAVLLGSVGGPKWGTGSVRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLK 117 Query: 143 HP--ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKP 200 D++I RE + IY G A+A ++ + E Sbjct: 118 EEIARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPE------------------ 159 Query: 201 CSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDG 260 +R+ R A E A R V V K N+++ E ++ EE G Sbjct: 160 -----VERVARVAFEAARKR-RKHVVSVDKANVLEVGE------FWRKTVEEVG------ 201 Query: 261 GPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGI 320 ++ ++ DA ++ PA +DV+ N+ GD +SD + G + Sbjct: 202 ---------RGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSL 252 Query: 321 GIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-MGWTEAADLIVKG 379 G+ P A++G +FE HG+AP AG+ NP + ILSA MML H G E A + Sbjct: 253 GLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMMLEHAFGLVELARKVEDA 312 Query: 380 MEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 + A+ D F ++ ++ Sbjct: 313 VAKALLE-------TPPPDLGGSAGTEAFTATVLRHL 342 >1WPW-A nrPDB Length = 336 Score = 313 bits (802), Expect = 8e-86, Method: Composition-based stats. Identities = 98/390 (25%), Positives = 168/390 (43%), Gaps = 60/390 (15%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I+GDGIG ++ +++ E I ++E+ G+++ YG+ LP ++ Sbjct: 4 VALIQGDGIGPEIVSKSKRILAKINE---LYSLPIEYIEVEAGDRALARYGE--ALPKDS 58 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 L +I + + +KG PVG + V LRQ D+Y +RP + G + + D Sbjct: 59 LKIIDKADIILKG----PVGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGN---VD 111 Query: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKR 208 ++I REN+ED+Y G E + +G+K + ++R Sbjct: 112 ILIVRENTEDLYKGFEHIV-----------------------SDGVAVGMKIITRFASER 148 Query: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKN 268 + + + +A+ R VT VHK N+M+ T+G F + + + Sbjct: 149 IAKVGLNFALRR-RKKVTCVHKANVMRITDGLFAEACRSVLK------------------ 189 Query: 269 PNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANI 328 ++ ++ DA ++ P +DVI N+ GD +SD + G +GIAP ANI Sbjct: 190 ----GKVEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDEASQIAGSLGIAPSANI 245 Query: 329 GDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKT 388 GD+ ALFE HG A AG++ NP + +LS MM M D +K NA Sbjct: 246 GDKKALFEPVHGAAFDIAGKNIGNPTAFLLSVSMMYERMYELSNDDRYIKASRALENAIY 305 Query: 389 VTYDFERLMDG--AKLLKCSEFGDAIIENM 416 + Y + + + + I + Sbjct: 306 LVYKERKALTPDVGGNATTDDLINEIYNKL 335 >3BLX-A nrPDB Length = 349 Score = 310 bits (793), Expect = 1e-84, Method: Composition-based stats. Identities = 98/390 (25%), Positives = 179/390 (45%), Gaps = 65/390 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDG+G ++T ++ + +A I W I + + + V+ E Sbjct: 20 VTLIPGDGVGKEITDSVRTIFEA-------ENIPIDWETINIKQTD---HKEGVY---EA 66 Query: 89 LDLIREYRVAIKGPLTTPVGG-GIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELT 147 ++ ++ ++ +KG TP G SLNVALR++LD+Y + + +G + + Sbjct: 67 VESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRI---PDI 123 Query: 148 DMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTK 207 D+++ REN+E ++G+E ++ E +K + T+ Sbjct: 124 DLIVIRENTEGEFSGLEHESVPGVVES-----------------------LKVMTRPKTE 160 Query: 208 RLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVK 267 R+ R A ++A +R SVT VHK NIMK +G F++ ++ ++E+ Sbjct: 161 RIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEY-------------- 206 Query: 268 NPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGAN 327 +I + +I D Q + +P ++DV+ ++ G + + AA +GG G+ GAN Sbjct: 207 -----PDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGAN 261 Query: 328 IGDECALFEA-THGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINA 386 G + A+FE + GQ+ NP ++ILS+ +ML H+G E A I K + I Sbjct: 262 FGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAE 321 Query: 387 KTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 T R + G+ ++F + II + Sbjct: 322 GKHT---TRDIGGSS--STTDFTNEIINKL 346 >3UDO-A nrPDB Length = 361 Score = 308 bits (788), Expect = 4e-84, Method: Composition-based stats. Identities = 98/409 (23%), Positives = 167/409 (40%), Gaps = 69/409 (16%) Query: 22 NVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQD 81 N + + + GDGIG V LK++ +K E G S YG Sbjct: 2 NAMKTYKVAVLAGDGIGPLVMKEALKILTFIAQKY---NFSFELNEAKIGGASIDAYG-- 56 Query: 82 VWLPAETLDLIREYRVAIKGPLTTPVGGGI-------RSLNVALRQELDLYICLRPVRYY 134 V L ETL L + + G + P + R+ + LR+ +L+ LRP + Y Sbjct: 57 VALSDETLKLCEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIY 116 Query: 135 QGT--PSPVKHP---ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIR 189 + SP+K+ + D++ RE + IY G K Sbjct: 117 ESLTHASPLKNEIIQKGVDILCVRELTGGIYFG------------------------KQD 152 Query: 190 FPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLA 249 + + +++ +R+ R A E A + V L+ K N++ + +++ +A Sbjct: 153 LGKESAYDTEIYTKKEIERIARIAFESARIR-KKKVHLIDKANVLASSI-LWREVVANVA 210 Query: 250 REEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYI 309 ++ ++I ++ + D QI+ P+ +DV+ C NL GD + Sbjct: 211 KDY--------------------QDINLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDIL 250 Query: 310 SDALAAQVGGIGIAPGANIGD-ECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRH-M 367 SD LAA G +G+ A++ D L+E G+AP A + NP + ILSA +ML++ Sbjct: 251 SDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNIANPIAQILSAALMLKYSF 310 Query: 368 GWTEAADLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 +AA I + A+ +T D + L E GD I+E + Sbjct: 311 KEEQAAQDIENAISLALAQGKMTKDL----NAKSYLNTDEMGDCILEIL 355 >4Y1P-A nrPDB Length = 337 Score = 307 bits (785), Expect = 8e-84, Method: Composition-based stats. Identities = 100/397 (25%), Positives = 161/397 (40%), Gaps = 72/397 (18%) Query: 28 IIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAE 87 ++ I+GDGIG +V ++ EK I ++E+ G+ + +G LP + Sbjct: 4 VVALIQGDGIGPEVVSKSKTILARLNEKF---SLPIEYIEVEAGDTTKNKFGD--ALPKD 58 Query: 88 TLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELT 147 +L +I + + +KG PVG + V LR DLY LRP + G + Sbjct: 59 SLRVIEKADMILKG----PVGETAADVVVKLRLMYDLYANLRPAKSLPGLENKF---GDV 111 Query: 148 DMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTK 207 D+++ REN+ED+Y G+E + +GIK + + Sbjct: 112 DILVVRENTEDLYKGLEHV-----------------------ISDGVTVGIKVITRAAST 148 Query: 208 RLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVK 267 R+ + A+ A+ + V VHK N+M+ T+G F + + + Sbjct: 149 RIAQVALNQALRR-KKKVVCVHKSNVMRITDGLFAESCRNVLK----------------- 190 Query: 268 NPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGAN 327 ++ ++ DA ++ P +DVI N GD +SD G +GI+P AN Sbjct: 191 -----GKVEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGISPSAN 245 Query: 328 IGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGW-------TEAADLIVKGM 380 IGD +LFE HG A AG++ NP + +LS MML M AA + + Sbjct: 246 IGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGDIRYNNAAKSLRDAI 305 Query: 381 EGAI-NAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 K +T D E AI + Sbjct: 306 YSVYSEGKYLTPDV------GGSSTTDEMISAIRSKI 336 >3FMX-X nrPDB Length = 364 Score = 303 bits (776), Expect = 8e-83, Method: Composition-based stats. Identities = 99/403 (24%), Positives = 166/403 (41%), Gaps = 65/403 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQD-VWLPAE 87 I I GDGIG++V P ++V++AA K + E S Y Q +P + Sbjct: 8 IAAIPGDGIGLEVLPEGIRVLEAAALKHGLA-LEFDTFE----WASCDYYLQHGKMMPDD 62 Query: 88 TLDLIREYRVAIKGPLT----TPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKH 143 + +++Y G + P + + R+E D Y+ +RPVR + G P + + Sbjct: 63 WAEQLKQYDAIYFGAVGWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALAN 122 Query: 144 PE--LTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPC 201 + D V+ REN+E Y+ + + + E+ +++ F Sbjct: 123 RKVGDIDFVVVRENTEGEYSSL--------GGIMFENTENEIVIQESIF----------- 163 Query: 202 SEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGG 261 + G R+++ A + A +R VT K N M + + Sbjct: 164 TRRGVDRILKYAFDLAEKRERKHVTSATKSNGMAISMPYW----------------DKRT 207 Query: 262 PWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIG 321 + P+ + D++ F+ Q P +DV+ NL GD +SD A G IG Sbjct: 208 EAMAAHYPHVSWDKQHIDILCARFVLQ----PERFDVVVASNLFGDILSDLGPACAGTIG 263 Query: 322 IAPGANIGDE---CALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMG-----WTEAA 373 IAP AN+ E +LFE HG+AP G++ NP ++I S +ML +G + A Sbjct: 264 IAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPIAMIWSGALMLEFLGQGDERYQRAH 323 Query: 374 DLIVKGMEGAINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 D ++ +E I +VT D L + G AI + + Sbjct: 324 DDMLNAIERVIADGSVTPDM------GGTLSTQQVGAAISDTL 360 >5GRH-B nrPDB Length = 354 Score = 292 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 97/392 (24%), Positives = 166/392 (42%), Gaps = 69/392 (17%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDGIG ++ + V A + + E++ + + +D+ Sbjct: 18 VTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNADE---EDIR---NA 64 Query: 89 LDLIREYRVAIKGPLTTP--VGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPEL 146 + IR RVA+KG + T + +S N LR LDLY V + + P V + Sbjct: 65 IMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYAN---VIHCKSLPGVVTRHKD 121 Query: 147 TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGT 206 D++I REN+E Y+ +E ++ + E +K ++ + Sbjct: 122 IDILIVRENTEGEYSSLEHESVAGVVES-----------------------LKIITKAKS 158 Query: 207 KRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKV 266 R+ A + A + R VT VHK NIMK +G F ++A Sbjct: 159 LRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY-------------- 204 Query: 267 KNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGA 326 +I +++I D Q++ RP ++DV+ NL G+ +++ A VGG G+ GA Sbjct: 205 ------PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGA 258 Query: 327 NIGDECALFE-ATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAIN 385 N G A+FE AT T A ++ NP + +L++ MML H+ A I K + +++ Sbjct: 259 NYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMD 318 Query: 386 AKTV-TYDFERLMDGAKLLKCSEFGDAIIENM 416 + + T D SE +I ++ Sbjct: 319 NENMHTPDI------GGQGTTSEAIQDVIRHI 344 >5HN5-A nrPDB Length = 353 Score = 281 bits (719), Expect = 3e-76, Method: Composition-based stats. Identities = 106/368 (28%), Positives = 155/368 (42%), Gaps = 68/368 (18%) Query: 27 PIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPA 86 + I GDGIG +V ++V+ A G + + E G Q G + Sbjct: 2 YRVAVIPGDGIGPEVIDGAVRVLKAV-----TGRVRFEYYE--GGVDVFQECGSPIR--E 52 Query: 87 ETLDLIREYRVAIKGPLTTPVG-GGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPE 145 E L+ IR + G TTP G RSL + LR+EL LY LR + + Sbjct: 53 EDLEEIRRSDAVLFGATTTPFDLPGYRSLILTLRKELGLYANLRIIPDLRT--------- 103 Query: 146 LTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEG 205 ++VI RENSE +Y GI + + ++ + EG Sbjct: 104 GREIVIVRENSEGLYFGIGAVVNGR------------------------AVDVRLITREG 139 Query: 206 TKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLK 265 +R+ R A+E A A +T VHK N++ + F+ ++A EE Sbjct: 140 AERIARFAVEQAKARG-SFITFVHKANVL-TGDKFFRRIVREVAGEE------------- 184 Query: 266 VKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPG 325 + ++D I D+F +++ P E+ VI NL GD +SD G IGI P Sbjct: 185 --------GVEVRDAIIDSFTIKLVRNPWEHGVILSENLFGDILSDLATVHAGSIGIVPS 236 Query: 326 ANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAIN 385 N GD ALFE HG+AP AG+ NP ILS M+L ++G LI + G + Sbjct: 237 GNYGDGIALFEPVHGSAPDIAGKGIANPIGAILSGAMLLDYLGLD--GSLIRAAVRGYVV 294 Query: 386 AKTVTYDF 393 +T D Sbjct: 295 NGELTPDM 302 >2G4O-A nrPDB Length = 337 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 107/394 (27%), Positives = 161/394 (40%), Gaps = 66/394 (16%) Query: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 + I GDGIG +VT +KV+DA V K G + G+ LP Sbjct: 4 LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTS-------YDLGARRFHATGE--VLPDSV 54 Query: 89 LDLIREYRVAIKGPLTTPV---GGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPE 145 + +R + + G + P G R L + LR ELD +I LRP R Y G SP+ Sbjct: 55 VAELRNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNP 114 Query: 146 LTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEG 205 D V+ RE +E Y G G ++ P + + G Sbjct: 115 GIDFVVVREGTEGPYTG-------------------NGGAIRVGTPNEVATEVSVNTAFG 155 Query: 206 TKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLK 265 +R+V A E A R +TLVHK N++ F G + ++ Sbjct: 156 VRRVVADAFERA-RRRRKHLTLVHKTNVLTFAGGLWLRTVDEVGE--------------- 199 Query: 266 VKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPG 325 ++ + DA ++ P +DVI NL GD I+D AA GGIG+A Sbjct: 200 -----CYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAAS 254 Query: 326 ANIGDECA---LFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEG 382 NI A +FE HG+AP AGQ +P + I+S ++L H+G +AA + + +E Sbjct: 255 GNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEHDAAARVDRAVEA 314 Query: 383 AINAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 + G++ L S+ G+ I + Sbjct: 315 HLA-----------TRGSERLATSDVGERIAAAL 337 >1ZOR-A nrPDB Length = 399 Score = 257 bits (657), Expect = 6e-69, Method: Composition-based stats. Identities = 89/418 (21%), Positives = 154/418 (36%), Gaps = 55/418 (13%) Query: 25 ENPIIPYIEGDGIGVDVTPAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVW 83 +NPI+ DG M +V+ EK I + G K + Sbjct: 7 KNPIVEL---DG------DEMARVMWKMIKEKLILPYLDIQLVYFDLGIKKRDETDDQIT 57 Query: 84 LPAETLDLIREYRVAIKGPLTTPVGG---------GIRSLNVALRQELDLYICLRPVRYY 134 + E I++Y V +K TP +S N +R LD + +P+ Sbjct: 58 I--EAAKAIKKYGVGVKCATITPDAERVKEYNLKKAWKSPNATIRAYLDGTVFRKPI-MV 114 Query: 135 QGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHC 194 + P VK + ++I R DIY +E K + +++ +E + +F + Sbjct: 115 KNVPPLVKRWKK-PIIIGRHAYGDIYNAVEAKVEGPAEVELVVRNKENKTLLVHKFEGNG 173 Query: 195 GIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFG 254 + E+ + ++ I YAI+ D + K I K FKD + + Sbjct: 174 VVMAMHNLEKSIRSFAQSCINYAISEKVD-IWFATKDTISKVYHAYFKDIFQEEVDKRKE 232 Query: 255 GELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALA 314 G + + ++ D Q +LR + ACMN GD +SD +A Sbjct: 233 ELEKAG--------------VNYRYMLIDDAAAQ-ILRSEGGMLWACMNYEGDIMSDMIA 277 Query: 315 AQVGGIGIAPGANIG-DECALFEATHGTAPKYA------GQDKVNPGSIILSAEMMLRHM 367 + G +G+ + D FEA HGT ++ + NP + I + +R Sbjct: 278 SGFGSLGLMTSVLVSPDGVYEFEAAHGTVRRHYYRYLKGEKTSTNPTASIFAWTGAIRKR 337 Query: 368 GW-------TEAADLIVKGMEGAINAKTVTYDFERLMDGA--KLLKCSEFGDAIIENM 416 G E AD + K + I + +T D + + K + EF D + +N+ Sbjct: 338 GELDGTPEVCEFADKLEKAVINTIESGVITKDLQPFTEPPIDKYVTLEEFIDEVKKNL 395 >5I96-A nrPDB Length = 458 Score = 236 bits (603), Expect = 1e-62, Method: Composition-based stats. Identities = 84/428 (19%), Positives = 149/428 (34%), Gaps = 72/428 (16%) Query: 30 PYIEGDGIGVDVTPAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 P +E DG M +++ EK I G + V + ++ Sbjct: 49 PVVEMDG------DEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI--DS 100 Query: 89 LDLIREYRVAIKGPLTTP---------VGGGIRSLNVALRQELDLYICLRPV------RY 133 ++Y VA+K TP + +S N ++ L + P+ R Sbjct: 101 ALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIQNILGGTVFREPIICKNIPRL 160 Query: 134 YQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKK---IRF 190 G P + I R D Y ++ AD A K++ ++ GVK+ F Sbjct: 161 VPGWTKP--------ITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNF 212 Query: 191 PEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAR 250 P ++E + +YAI + + + K I+K +G FKD ++ Sbjct: 213 PAGGVGMGMYNTDESISGFAHSCFQYAIQ-KKWPLYMSTKNTILKAYDGRFKDIFQEIFD 271 Query: 251 EEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYIS 310 + + + W + + D + Q+L + V AC N +GD S Sbjct: 272 KHYKTDFDKNKIW-------------YEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQS 317 Query: 311 DALAAQVGGIGIAPGANIGDECALF--EATHGTAPKYAGQDK------VNPGSIILSAEM 362 D LA G +G+ + + EA HGT ++ + + NP + I + Sbjct: 318 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 377 Query: 363 MLRHMGWTE-------AADLIVKGMEGAINAKTVTYDFERLMDG-------AKLLKCSEF 408 L H G + A ++ K + + +T D + G L ++F Sbjct: 378 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDF 437 Query: 409 GDAIIENM 416 D I N+ Sbjct: 438 LDTIKSNL 445 >4AOY-A nrPDB Length = 402 Score = 231 bits (589), Expect = 4e-61, Method: Composition-based stats. Identities = 79/417 (18%), Positives = 148/417 (35%), Gaps = 55/417 (13%) Query: 29 IPYIEGDGIGVDVTPAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAE 87 +P +E DG M +++ E + +++ G ++ V + + Sbjct: 8 VPLVEMDG------DEMTRIIWRLIKENLLEPYIELNTEYYDLGLENRDKTEDQVTI--D 59 Query: 88 TLDLIREYRVAIKGPLTTPVGGG---------IRSLNVALRQELDLYICLRPVRYYQGTP 138 I++Y V +K TP +S N +R LD + P+ + Sbjct: 60 AARAIQKYGVGVKCATITPNAQRVEEYNLKKMWKSPNGTIRAILDGTVFRAPIVV--NSI 117 Query: 139 SPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGI 198 P + I R D+Y +E+ SA +++ F E V + E G G+ Sbjct: 118 KPFVKGWKKPISIARHAYGDVYKNVEYYVPSAGKAELV-FTSENGEVSRQTIHEFDGPGV 176 Query: 199 ---KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGG 255 +++ + RA YA+ ++D + K I K + FKD ++ E+ Sbjct: 177 IMGMHNTDKSIRSFARACFNYALDMNQD-LWFSTKDTISKTYDHRFKDIFQEIYENEYKE 235 Query: 256 ELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAA 315 + +I D +A ++R V AC N +GD +SD +A+ Sbjct: 236 KFEAKNL--------QYFYTLIDDAVAR------IIRSEGGMVWACKNYDGDVMSDMVAS 281 Query: 316 QVGGIGIAPGANIG-DECALFEATHGTAPKYAGQDK------VNPGSIILSAEMMLRHMG 368 G + + + D FEA HGT ++ + N + I + L+ G Sbjct: 282 AFGSLAMMTSVLVSPDGKYEFEAAHGTVTRHYYKHLKGEETSTNSMATIFAWTGALKKRG 341 Query: 369 WT-------EAADLIVKGMEGAINAKTVTYDFERLMDGA--KLLKCSEFGDAIIENM 416 + A + + I +T D L + K++ +F I + Sbjct: 342 ELDGIKELVDFATKLEQASVQTIENGVMTKDLASLSEVPEKKIVNTEDFLKEIRKTF 398 >4HCX-A nrPDB Length = 409 Score = 228 bits (582), Expect = 3e-60, Method: Composition-based stats. Identities = 87/423 (20%), Positives = 146/423 (34%), Gaps = 67/423 (15%) Query: 30 PYIEGDGIGVDVTPAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 P +E DG M +V+ + I G + V + + Sbjct: 12 PVVELDG------DEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTI--DA 63 Query: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNV---------ALRQELDLYICLRPV------RY 133 I+++ V +K TP + N+ +R L I P+ R Sbjct: 64 AYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRL 123 Query: 134 YQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIR---F 190 G P +VI R D Y +K D + + Sbjct: 124 VPGWTKP--------IVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSI 175 Query: 191 PEHCGIGIKPCS-EEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLA 249 PE G+ + + +E + RA+ Y + N + V L K I+K +G FKD ++ Sbjct: 176 PEDGGVVLGMYNFKESIRDFARASFSYGL-NAKWPVYLSTKNTILKAYDGMFKDEFERVY 234 Query: 250 REEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYI 309 EEF + G + + +I D++A L+ V AC N +GD Sbjct: 235 EEEFKAQFEAAGLTYEHR--------LIDDMVA------ACLKWEGGYVWACKNYDGDVQ 280 Query: 310 SDALAAQVGGIGIAPGANIGDECALF--EATHGTAPKYAGQ------DKVNPGSIILSAE 361 SD +A G +G+ + + EA HGT ++ Q NP + I + Sbjct: 281 SDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWT 340 Query: 362 MMLRHMGWTEAADLIVKGMEG-------AINAKTVTYDFERLMDGAK-LLKCSEFGDAII 413 L+H G + ++ + + +T D L+ + L EF DAI Sbjct: 341 RGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIA 400 Query: 414 ENM 416 +N+ Sbjct: 401 DNL 403 >3US8-A nrPDB Length = 427 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 84/420 (20%), Positives = 154/420 (36%), Gaps = 58/420 (13%) Query: 26 NPIIPYIEGDGIGVDVTPAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWL 84 NP++ DG M +++ +K + G ++ V + Sbjct: 31 NPVVEL---DG------DEMTRIIWQFIKDKLIHPYLDLDLEYYDLGVENRDATDDQVTI 81 Query: 85 PAETLDLIREYRVAIKGPLTTPVGGG---------IRSLNVALRQELDLYICLRPVRYYQ 135 + + I+++ V +K TP G +S N +R L I P+ + Sbjct: 82 --DAANAIKKHGVGVKCATITPDEGRVEEFKLKKMWKSPNGTIRNILGGVIFREPI-ICK 138 Query: 136 GTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCG 195 P V +++ R D Y ++K + IKF+ E+ + + G Sbjct: 139 NVPRLVPGWTK-PIIVGRHAFGDQYRATDFKF-PGKGKLSIKFVGEDGQTIEHDVYDAPG 196 Query: 196 IGI---KPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREE 252 G+ +E RA+ Y + + V L K I+K +G FKD ++ EE Sbjct: 197 AGVALAMYNLDESITEFARASFNYGLQR-KVPVYLSTKNTILKAYDGRFKDIFQKVFDEE 255 Query: 253 FGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDA 312 F + W + + +I D++A A L+ + V AC N +GD SD Sbjct: 256 FAAQFKAEKLWYEHR--------LIDDMVASA------LKWSGGYVWACKNYDGDVQSDI 301 Query: 313 LAAQVGGIGIAPGANIGDECALF--EATHGTAPKYAGQDK------VNPGSIILSAEMML 364 +A G +G+ + + EA HGT ++ Q + N + I + L Sbjct: 302 VAQGFGSLGLMTSVLMTPDGKTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGL 361 Query: 365 RHMGWTE-------AADLIVKGMEGAINAKTVTYDFERLMDGAK-LLKCSEFGDAIIENM 416 H + ++ + + + + +T D L+ + L + F D I EN+ Sbjct: 362 AHRAKLDGNAELAKFSETLERVCVDTVESGFMTKDLALLIGPDQPWLSTTGFLDKIDENL 421 >6BL1-B nrPDB Length = 425 Score = 220 bits (560), Expect = 9e-58, Method: Composition-based stats. Identities = 70/409 (17%), Positives = 145/409 (35%), Gaps = 54/409 (13%) Query: 43 PAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKG 101 M +++ + EK ++ G ++ V + + I+++ V +K Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVT--KDAAEAIKKHNVGVKC 73 Query: 102 PLTTPVGGG---------IRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIF 152 TP +S N +R L + R + P V + ++I Sbjct: 74 ATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVF-REAIICKNIPRLVSGW-VKPIIIG 131 Query: 153 RENSEDIYAGIEWKADSADAEKVIKFLREE---MGVKKIRFPEHCGIGIKPCS-EEGTKR 208 R D Y ++ ++ + + F E G+ + + ++ + Sbjct: 132 RHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIED 191 Query: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKN 268 ++ + A++ + L K I+K +G FKD ++ +++ + W + + Sbjct: 192 FAHSSFQMALSKG-WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHR- 249 Query: 269 PNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANI 328 +I D++A A + + AC N +GD SD++A G +G+ + Sbjct: 250 -------LIDDMVAQAM------KSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLV 296 Query: 329 GDECALF--EATHGTAPKYAG------QDKVNPGSIILSAEMMLRHMGWTE-------AA 373 + EA HGT ++ + NP + I + L H + A Sbjct: 297 CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFA 356 Query: 374 DLIVKGMEGAINAKTVTYDFERLMDG------AKLLKCSEFGDAIIENM 416 + + + I A +T D + G + L EF D + EN+ Sbjct: 357 NALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL 405 >2QFY-A nrPDB Length = 427 Score = 208 bits (528), Expect = 5e-54, Method: Composition-based stats. Identities = 69/421 (16%), Positives = 143/421 (33%), Gaps = 59/421 (14%) Query: 30 PYIEGDGIGVDVTPAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 P +E DG M +++ D +K + +S + + Sbjct: 24 PVVELDG------DEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKIT--QDA 75 Query: 89 LDLIREYRVAIKGPLTTP---------VGGGIRSLNVALRQELDLYICLRPVRYYQGTPS 139 + I++Y V IK TP + +S N +R L + P+ P Sbjct: 76 AEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPI-VIPRIPR 134 Query: 140 PVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVI-----KFLREEMGVKKIRFPEHC 194 V E ++I R D Y + + +++ + +K + Sbjct: 135 LVPRWEK-PIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDYKGSG 193 Query: 195 GIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFG 254 ++E + ++ + AI + ++ L K I+K +G FKD ++ ++ Sbjct: 194 VAMAMYNTDESIEGFAHSSFKLAID-KKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYK 252 Query: 255 GELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALA 314 + G I + + D + Q++ + ++A N +GD SD +A Sbjct: 253 SKFEQLG-------------IHYEHRLIDDMVAQMIKSKGGF-IMALKNYDGDVQSDIVA 298 Query: 315 AQVGGIGIAPGANIGDECALF--EATHGTAPKYAGQ------DKVNPGSIILSAEMMLRH 366 G +G+ + + F EA HGT ++ + N + I + L Sbjct: 299 QGFGSLGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLK 358 Query: 367 MGWTE-------AADLIVKGMEGAI-NAKTVTYDFE---RLMDGAKLLKCSEFGDAIIEN 415 G + A+++ + +T D + + + EF DA+ + Sbjct: 359 RGELDNTPALCKFANILESATLNTVQQDGIMTKDLALACGNNERSAYVTTEEFLDAVEKR 418 Query: 416 M 416 + Sbjct: 419 L 419 >2UXQ-A nrPDB Length = 402 Score = 204 bits (520), Expect = 4e-53, Method: Composition-based stats. Identities = 77/415 (18%), Positives = 144/415 (34%), Gaps = 53/415 (12%) Query: 30 PYIEGDGIGVDVTPAMLKVV-DAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 P +E DG M +V+ +K + G + + + + Sbjct: 8 PLVELDG------DEMTRVLWPLIKDKLLLPFIDLQTEYYDLGIEERDRTNDQITI--DA 59 Query: 89 LDLIREYRVAIKGPLTTPV---------GGGIRSLNVALRQELDLYICLRPVRYYQGTPS 139 + I++Y V +K TP +S N +R LD + +P+ + Sbjct: 60 AEAIKKYGVGVKNATITPNQDRVEEYGLKEQWKSPNATVRAMLDGTVFRKPI-MVKNIKP 118 Query: 140 PVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLRE--EMGVKKIRFPEHCGIG 197 V+ + +V+ R D Y E A++ +++ + E + E + Sbjct: 119 SVRSWQK-PIVVGRHAYGDFYKNAEIFAEAGGKLEIVVTDKNGKETRQTIMEVDEPAIVQ 177 Query: 198 IKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGEL 257 + RA EY++ D K I K + FK ++ +E+ + Sbjct: 178 GIHNTVASIGHFARACFEYSLDQKID-CWFATKDTISKQYDQRFKIIFEEIFAQEYKEKF 236 Query: 258 IDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQV 317 G +I DV+A + + AC N +GD +SD +A+ Sbjct: 237 AAAGIE--------YFYTLIDDVVARMM------KTEGGMLWACKNYDGDVMSDMVASAF 282 Query: 318 GGIGIAPGANIGD-ECALFEATHGTAPKYAGQDK------VNPGSIILSAEMMLRHMGWT 370 G + + + +EA HGT ++ Q NP ++I + LR G Sbjct: 283 GSLAMMSSVLVSPYGYFEYEAAHGTVQRHYYQHLKGERTSTNPVALIYAWTGALRKRGEL 342 Query: 371 EAA-------DLIVKGMEGAINAKTVTYDFERLMDGA--KLLKCSEFGDAIIENM 416 + D + I + +T D R+ + A K+L EF D + + + Sbjct: 343 DGTPDLCAFCDSLEAITIECIESGYMTGDLARICEPAAIKVLDSIEFIDELGKRL 397 >4JQP-A nrPDB Length = 342 Score = 31.7 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 8/66 (12%) Query: 294 AEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECALFEAT--HGTAPKYAGQDKV 351 ++D++ M D V +G+ G N+ + + HGTA AG+ V Sbjct: 270 GDFDLVVAM------YHDQGHGPVKVLGLEAGVNVTVGLEVIRTSVDHGTAFDIAGKGVV 323 Query: 352 NPGSII 357 + GS++ Sbjct: 324 DEGSML 329 >5I24-A nrPDB Length = 836 Score = 31.7 bits (70), Expect = 0.67, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 21/58 (36%), Gaps = 7/58 (12%) Query: 79 GQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQG 136 G+ P +T I + T G R + +Q+LD + LRP + Sbjct: 391 GEPEMHPEDTQHAIGDAD-------TVHNAYGHRWAEMLYQQQLDQFPELRPFIMMRA 441 >6BYS-B nrPDB Length = 379 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 27/212 (12%), Positives = 67/212 (31%), Gaps = 17/212 (8%) Query: 67 EIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYI 126 E+YT E + +P + + + K L + + RS D++ Sbjct: 101 EVYTEEDAASYV--RKVIPKDYKTMAALAKAIEKNVLFSHLDDNERS---------DIFD 149 Query: 127 CLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVK 186 + PV + G + E + + + D+Y EW + + + Sbjct: 150 AMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPR 209 Query: 187 KIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGY 246 + + + +R++ + + + + K +I++ + K Sbjct: 210 AATVKAKTNVKLWGIDRDSYRRIL---MGSTLRKRKMYEEFLSKVSILESLD---KWERL 263 Query: 247 QLAREEFGGELIDGGPWLKVKNPNTGKEIVIK 278 +A + DG + P I+++ Sbjct: 264 TVADALEPVQFEDGQKIVVQGEPGDEFFIILE 295 >2QCS-B nrPDB Length = 291 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 27/212 (12%), Positives = 67/212 (31%), Gaps = 17/212 (8%) Query: 67 EIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYI 126 E+YT E + +P + + + K L + + RS D++ Sbjct: 12 EVYTEEDAASYV--RKVIPKDYKTMAALAKAIEKNVLFSHLDDNERS---------DIFD 60 Query: 127 CLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVK 186 + PV + G + E + + + D+Y EW + + + Sbjct: 61 AMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPR 120 Query: 187 KIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGY 246 + + + +R++ + + + + K +I++ + K Sbjct: 121 AATVKAKTNVKLWGIDRDSYRRIL---MGSTLRKRKMYEEFLSKVSILESLD---KWERL 174 Query: 247 QLAREEFGGELIDGGPWLKVKNPNTGKEIVIK 278 +A + DG + P I+++ Sbjct: 175 TVADALEPVQFEDGQKIVVQGEPGDEFFIILE 206 >5L22-B nrPDB Length = 572 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 29/87 (33%), Gaps = 9/87 (10%) Query: 256 ELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAA 315 + + + VK P EI + +V+ P E N+N + A Sbjct: 313 KFLRFKREVSVKLPEPKGEIELSNVVV---------VPPEGKTPVLRNINMRILPGEFVA 363 Query: 316 QVGGIGIAPGANIGDECALFEATHGTA 342 +G G + + ++ HGT Sbjct: 364 IIGPSGSGKSSLVRTILGIWLPVHGTV 390 >6AJJ-A nrPDB Length = 943 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 17/36 (47%) Query: 304 LNGDYISDALAAQVGGIGIAPGANIGDECALFEATH 339 + G I+ AL A +GG+ IA I A F H Sbjct: 217 VFGTVIAAALPAIIGGLAIAGALGIMRLVAEFTPVH 252 >2G3M-A nrPDB Length = 693 Score = 29.0 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 23/158 (14%), Positives = 49/158 (31%), Gaps = 8/158 (5%) Query: 149 MVIFRENSEDIYA---GIEWKADSADAEKVIKFLRE--EMGVKKIRFPEHCGIGIKPCSE 203 ++ EN + +Y G + E+ I + E+G+ ++ + + Sbjct: 3 ILKIYEN-KGVYKVVIGEPFPPIEFPLEQKISSNKSLSELGLTIVQQGNKVIVEKSLDLK 61 Query: 204 EGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDW--GYQLAREEFGGELIDGG 261 E L A E R + V G K+ + + + G + Sbjct: 62 EHIIGLGEKAFELDRKRKRYVMYNVDAGAYKKYQDPLYVSIPLFISVKDGVATGYFFNSA 121 Query: 262 PWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVI 299 + + VI + D+ ++ P DV+ Sbjct: 122 SKVIFDVGLEEYDKVIVTIPEDSVEFYVIEGPRIEDVL 159 >5CWS-E nrPDB Length = 247 Score = 28.6 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 26/66 (39%), Gaps = 9/66 (13%) Query: 8 PAQGKKITLQNGKLNVPENPI---------IPYIEGDGIGVDVTPAMLKVVDAAVEKAYK 58 PAQG ++ +L V E DG+G ++ K+++ ++ Sbjct: 168 PAQGSRLEELWSRLIVLRGYAEDLKDQINQAGITESDGLGEEIEAKAKKILEDYDKQLQH 227 Query: 59 GERKIS 64 ++++ Sbjct: 228 LKKQVE 233 >2XV4-S nrPDB Length = 534 Score = 28.6 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 17/42 (40%) Query: 354 GSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFER 395 ILSA ML H + A+LI + K + +R Sbjct: 425 TVNILSAARMLLHRCYKSIANLIERRQFETKENKRLLEKSQR 466 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.126 0.331 Lambda K H 0.267 0.0382 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,329,862 Number of Sequences: 36641 Number of extensions: 632255 Number of successful extensions: 2149 Number of sequences better than 10.0: 56 Number of HSP's better than 10.0 without gapping: 83 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1698 Number of HSP's gapped (non-prelim): 125 length of query: 416 length of database: 10,336,785 effective HSP length: 100 effective length of query: 316 effective length of database: 6,672,685 effective search space: 2108568460 effective search space used: 2108568460 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.8 bits)