BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08179 (212 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1JKX-A nrPDB 439 e-124 3TQR-A nrPDB 228 1e-60 3AUF-A nrPDB 196 6e-51 4DS3-A nrPDB 185 1e-47 1MEJ-B nrPDB 166 9e-42 2YWR-A nrPDB 163 4e-41 4S1N-A nrPDB 132 1e-31 3KCQ-A nrPDB 132 1e-31 3P9X-A nrPDB 130 3e-31 3AV3-A nrPDB 130 4e-31 5CJJ-A nrPDB 125 1e-29 3DA8-A nrPDB 112 1e-25 3W7B-A nrPDB 93 1e-19 3O1L-A nrPDB 72 2e-13 3NRB-A nrPDB 69 1e-12 3LOU-A nrPDB 69 2e-12 3OBI-A nrPDB 67 6e-12 3N0V-A nrPDB 66 9e-12 4XD0-A nrPDB 51 3e-07 5VYT-A nrPDB 51 4e-07 5UIL-A nrPDB 50 6e-07 5UAI-A nrPDB 49 1e-06 4LY0-A nrPDB 47 5e-06 3TQQ-A nrPDB 47 8e-06 4TT8-A nrPDB 45 3e-05 1FMT-A nrPDB 44 4e-05 4IQF-A nrPDB 44 4e-05 4WKG-A nrPDB 43 8e-05 5J63-A nrPDB 43 8e-05 5JNF-C nrPDB 43 1e-04 5ES6-A nrPDB 42 1e-04 5ES8-A nrPDB 42 2e-04 2BW0-A nrPDB 41 4e-04 5VYQ-A nrPDB 40 5e-04 4NV1-C nrPDB 40 5e-04 1S3I-A nrPDB 39 0.001 3Q0I-A nrPDB 38 0.003 3R8X-A nrPDB 36 0.011 1VMI-A nrPDB 35 0.028 4YFV-A nrPDB 32 0.21 6NBP-A nrPDB 31 0.50 4NAV-D nrPDB 27 7.0 >1JKX-A nrPDB Length = 212 Score = 439 bits (1128), Expect = e-124, Method: Compositional matrix adjust. Identities = 212/212 (100%), Positives = 212/212 (100%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA Sbjct: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT Sbjct: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV Sbjct: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 Query: 181 ISWFADGRLKMHENAAWLDGQRLPPQGYAADE 212 ISWFADGRLKMHENAAWLDGQRLPPQGYAADE Sbjct: 181 ISWFADGRLKMHENAAWLDGQRLPPQGYAADE 212 >3TQR-A nrPDB Length = 215 Score = 228 bits (581), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 113/209 (54%), Positives = 147/209 (70%), Gaps = 1/209 (0%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + IVVLISGNG+NLQAII A + + +RAV SN+ADA+GL+RA+QA I TH + Sbjct: 6 LPIVVLISGNGTNLQAIIGAIQKG-LAIEIRAVISNRADAYGLKRAQQADIPTHIIPHEE 64 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 F SR ++ L ID Y P ++VLAGFMR L AFVSHY+GR++NIHPSLLPKY GL+T Sbjct: 65 FPSRTDFESTLQKTIDHYDPKLIVLAGFMRKLGKAFVSHYSGRMINIHPSLLPKYTGLNT 124 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 H +AL G+ EHG SVH+VT++LD GP+I QA++ + D+ + + RV EH IYP V Sbjct: 125 HERALAAGETEHGVSVHYVTEDLDAGPLICQARLSITPQDTPETLKTRVHALEHIIYPEV 184 Query: 181 ISWFADGRLKMHENAAWLDGQRLPPQGYA 209 +SWFA GRL H N +LDG+ L G+A Sbjct: 185 LSWFAAGRLNYHNNQVFLDGKPLAKSGHA 213 >3AUF-A nrPDB Length = 229 Score = 196 bits (498), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 94/189 (49%), Positives = 130/189 (68%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + I VLISG+G+NLQAI+D C+ +I G V V S++ADA+GLERAR+AG+ + +A Sbjct: 23 IRIGVLISGSGTNLQAILDGCREGRIPGRVAVVISDRADAYGLERARRAGVDALHMDPAA 82 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 + SR A+D L + Y D+V LAG+MR++ ++ + R+LNIHPSLLP +PGL Sbjct: 83 YPSRTAFDAALAERLQAYGVDLVCLAGYMRLVRGPMLTAFPNRILNIHPSLLPAFPGLEA 142 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 RQALE+G + G +VHFVT +D GP+ILQA VPV GD+ +D+ R+ +EH IYP Sbjct: 143 QRQALEHGVKVAGCTVHFVTAGVDEGPIILQAAVPVLEGDTVEDLRRRILAEEHRIYPEA 202 Query: 181 ISWFADGRL 189 I FA+GRL Sbjct: 203 IRLFAEGRL 211 >4DS3-A nrPDB Length = 209 Score = 185 bits (470), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 87/186 (46%), Positives = 126/186 (67%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +V+ ISG GSN++A+I A + + AVFS+KA+A GL +A AGIAT F Sbjct: 9 RVVIFISGGGSNMEALIRAAQAPGFPAEIVAVFSDKAEAGGLAKAEAAGIATQVFKRKDF 68 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 S+EA++ ++ +D+ PD++ LAG+MR+LS F++ Y GR+LNIHPSLLP +PGLHTH Sbjct: 69 ASKEAHEDAILAALDVLKPDIICLAGYMRLLSGRFIAPYEGRILNIHPSLLPLFPGLHTH 128 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 ++AL+ G + G +VH VT+ +D GP++ QA VPV GD+ + + ARV EH +YPL + Sbjct: 129 QRALDAGMKLAGCTVHLVTEGMDEGPILAQAAVPVLDGDTAETLAARVLKAEHRLYPLAL 188 Query: 182 SWFADG 187 FA G Sbjct: 189 QKFAAG 194 >1MEJ-B nrPDB Length = 223 Score = 166 bits (419), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 84/203 (41%), Positives = 123/203 (60%), Gaps = 2/203 (0%) Query: 3 IVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFD 62 + VLISG GSNLQA+ID+ + + V SNKA GL++A +AGI T + + Sbjct: 14 VAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYK 73 Query: 63 SREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHR 122 +R +D + ++ ++ D+V LAGFMRILS FV + G++LNIHPSLLP + G + H Sbjct: 74 NRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHE 133 Query: 123 QALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVIS 182 QALE G G +VHFV +++D G +ILQ VPV GD+ ++ RV+ EH I+P + Sbjct: 134 QALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQ 193 Query: 183 WFADGRLKMHENA--AWLDGQRL 203 A G +++ EN W+ + L Sbjct: 194 LVASGTVQLGENGKICWVKEEPL 216 >2YWR-A nrPDB Length = 216 Score = 163 bits (413), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 75/189 (39%), Positives = 117/189 (61%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + I VL+SG GSNLQAIIDA ++ K+ ++ V S+ A+ +ER ++ + + Sbjct: 2 LKIGVLVSGRGSNLQAIIDAIESGKVNASIELVISDNPKAYAIERCKKHNVECKVIQRKE 61 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 F S++ ++ + E+ ++VVLAGFMRILS F+ ++ +++NIHPSL+P + GLH Sbjct: 62 FPSKKEFEERMALELKKKGVELVVLAGFMRILSHNFLKYFPNKVINIHPSLIPAFQGLHA 121 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 +QA+E G + G +VH V + +D GPVI+QA VPV D E+ + R+ EH I P Sbjct: 122 QKQAVEFGVKFSGCTVHIVDESVDAGPVIVQAVVPVLPEDDENTLADRILKWEHKILPQT 181 Query: 181 ISWFADGRL 189 + WFA R+ Sbjct: 182 VQWFAQDRI 190 >4S1N-A nrPDB Length = 184 Score = 132 bits (332), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 68/181 (37%), Positives = 104/181 (57%), Gaps = 7/181 (3%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 I V SGNGSN Q I + + V VFS+ DA+ LERA+Q G+ ++ F Sbjct: 6 KIAVFASGNGSNFQVIAE-------EFPVEFVFSDHRDAYVLERAKQLGVLSYAFELKEF 58 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 +S+ Y+ L+ ++ + D+V LAG+M+I+ P +S Y GR++NIHP+ LP++PG H Sbjct: 59 ESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIHPAYLPEFPGAHGI 118 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 A G + G ++H+V +D G VI Q +VP A D+ D AR+ E+ +YP V+ Sbjct: 119 EDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFEARIHEAEYRLYPEVV 178 Query: 182 S 182 Sbjct: 179 K 179 >3KCQ-A nrPDB Length = 215 Score = 132 bits (331), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 71/194 (36%), Positives = 108/194 (55%), Gaps = 5/194 (2%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + + VLISG GSNL+A+ A T + + V SN A+A GL A+ GI T + Sbjct: 9 LRVGVLISGRGSNLEALAKAFSTEESSVVISCVISNNAEARGLLIAQSYGIPTFVVKRKP 68 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 D H++D+ V LAGFM IL FV+ + +++NIHPSLLP + GL+ Sbjct: 69 LDIEHISTVLREHDVDL-----VCLAGFMSILPEKFVTDWHHKIINIHPSLLPSFKGLNA 123 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 QA + G + G ++H+V ELD GP+I+QA VPV D+ + + +R+ EH YP Sbjct: 124 QEQAYKAGVKIAGCTLHYVYQELDAGPIIMQAAVPVLREDTAESLASRILAAEHVCYPKG 183 Query: 181 ISWFADGRLKMHEN 194 + A ++K+ ++ Sbjct: 184 VKLIAQDKIKLCDD 197 >3P9X-A nrPDB Length = 211 Score = 130 bits (328), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 62/177 (35%), Positives = 104/177 (58%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 + + SG+G+N +AII + K ++ V + ++K A +ER + I L + Sbjct: 4 RVAIFASGSGTNAEAIIQSQKAGQLPCEVALLITDKPGAKVVERVKVHEIPVCALDPKTY 63 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 S+EAY+ E++ ++ D VVLAG+MR++ P + Y GR++NIHPSLLP +PGLH Sbjct: 64 PSKEAYEIEVVQQLKEKQIDFVVLAGYMRLVGPTLLGAYEGRIVNIHPSLLPAFPGLHAI 123 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYP 178 QA+ + G ++H+V + +D GP+I Q V + D+ + +T ++Q EH +YP Sbjct: 124 EQAIRANVKVTGVTIHYVDEGMDTGPIIAQEAVSIEEEDTLETLTTKIQAVEHRLYP 180 >3AV3-A nrPDB Length = 212 Score = 130 bits (327), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 64/193 (33%), Positives = 104/193 (53%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 + V SG+G+N QAI+DA K + V + ++ A +ERA + + + Sbjct: 5 RLAVFASGSGTNFQAIVDAAKRGDLPARVALLVCDRPGAKVIERAARENVPAFVFSPKDY 64 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 S+ A++ E++ E+ D + LAG+MR++ P +S Y G+++NIHPSLLP +PG Sbjct: 65 PSKAAFESEILRELKGRQIDWIALAGYMRLIGPTLLSAYEGKIVNIHPSLLPAFPGKDAI 124 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA G E G +VH+V + +D GPVI Q VP+ G+ + + R+ EH +YP V+ Sbjct: 125 GQAYRAGVSETGVTVHYVDEGMDTGPVIAQRVVPIVPGEPIEALEERIHQVEHELYPTVL 184 Query: 182 SWFADGRLKMHEN 194 + + E Sbjct: 185 RMLLGEKEQQEER 197 >5CJJ-A nrPDB Length = 191 Score = 125 bits (314), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 73/189 (38%), Positives = 113/189 (59%), Gaps = 7/189 (3%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKI-KGTVRAVFS--NKADAFGLERARQAGIATHTLI 57 + + VL SGNGSNL+ I++ I + T V NK DAFG++RA++ G+ T + Sbjct: 6 VKLAVLFSGNGSNLENILEKLHKKTIGENTYEIVLCLCNKKDAFGIQRAKKFGLNTVIID 65 Query: 58 ASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPG 117 A+++RE +D L+ +I ++ VLAGFMRILSP F + + +N+HPSLLP + G Sbjct: 66 HKAYNTREEFDTILVQKIKESGANLTVLAGFMRILSPVFTKNI--KAINLHPSLLPLFKG 123 Query: 118 LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIY 177 H +++ E+ + G SVH+V++ELDGG +I Q K S ++ ++ + EH I Sbjct: 124 AHAIKESYESDMKVAGVSVHWVSEELDGGMIIAQ-KAFEKRNLSFEEFEEKIHSLEHEIL 182 Query: 178 PL-VISWFA 185 PL VI F+ Sbjct: 183 PLSVIEIFS 191 >3DA8-A nrPDB Length = 215 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 66/173 (38%), Positives = 95/173 (54%), Gaps = 2/173 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +VVL SG GS L++++DA V AV ++ + E A +A + T+ + Sbjct: 14 RLVVLASGTGSLLRSLLDAA-VGDYPARVVAVGVDR-ECRAAEIAAEASVPVFTVRLADH 71 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 SR+A+D + + PD+VV AGFMRIL P F+S + GR LN HP+LLP +PG H Sbjct: 72 PSRDAWDVAITAATAAHEPDLVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGV 131 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEH 174 AL G + G +VH V D GP++ Q VPV GD E+ + R++ E Sbjct: 132 ADALAYGVKVTGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTER 184 >3W7B-A nrPDB Length = 285 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 59/190 (31%), Positives = 96/190 (50%), Gaps = 3/190 (1%) Query: 5 VLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSR 64 +L+S L ++ + ++ +R V SN D E + GI H + Sbjct: 93 ILVSKPAHALLELLWRYRVGELPMELRLVISNHPD--HREEVERFGIPYHHVPVEKGRKE 150 Query: 65 EAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQA 124 EA +R ++ ++ ++VVLA +M+ILSP FV + R++NIH S LP + G +RQA Sbjct: 151 EAEER-ILALLEAEGVELVVLARYMQILSPGFVERFPMRIINIHHSFLPAFAGADPYRQA 209 Query: 125 LENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWF 184 E G + G + H+VT+ELD GP+I Q V V S ++ + E + + W Sbjct: 210 YERGVKLIGATAHYVTEELDQGPIIEQDVVRVSHRHSVREMKRLGRELERTVLARAVRWH 269 Query: 185 ADGRLKMHEN 194 + R+ +HEN Sbjct: 270 LEDRILVHEN 279 >3O1L-A nrPDB Length = 302 Score = 71.6 bits (174), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 52/192 (27%), Positives = 91/192 (47%), Gaps = 3/192 (1%) Query: 3 IVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFD 62 +V++ S L ++ ++++ + V SN D + I + + D Sbjct: 108 VVLMASRESHCLADLLHRWHSDELDCDIACVISNHQDLRSM--VEWHDIPYYHVPVDPKD 165 Query: 63 SREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHR 122 A+ E+ + + DVVVLA +M+IL P YA +++NIH S LP + G + Sbjct: 166 KEPAF-AEVSRLVGHHQADVVVLARYMQILPPQLCREYAHQVINIHHSFLPSFVGAKPYH 224 Query: 123 QALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVIS 182 QA G + G + H+VT+ELD GP+I Q V V DS +++ + E + + Sbjct: 225 QASLRGVKLIGATCHYVTEELDAGPIIEQDVVRVSHRDSIENMVRFGRDVEKMVLARGLR 284 Query: 183 WFADGRLKMHEN 194 + R+ +H+N Sbjct: 285 AHLEDRVLVHDN 296 >3NRB-A nrPDB Length = 287 Score = 68.9 bits (167), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 40/127 (31%), Positives = 67/127 (52%) Query: 63 SREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHR 122 ++ A + ++ + + D++VLA +M+ILS + +GR +NIH S LP + G + Sbjct: 149 TKAAQESQIKNIVTQSQADLIVLARYMQILSDDLSAFLSGRCINIHHSFLPGFKGAKPYH 208 Query: 123 QALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVIS 182 QA G + G + HFVT +LD GP+I Q V DS +D+ + + E + + Sbjct: 209 QAHTRGVKLIGATAHFVTADLDEGPIIAQDVEHVSHRDSAEDLVRKGRDIERRVLSRAVL 268 Query: 183 WFADGRL 189 F + RL Sbjct: 269 LFLEDRL 275 >3LOU-A nrPDB Length = 292 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 3/150 (2%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +++++S L ++ K ++K + + SN D L A Q G+ +A Sbjct: 97 KVLIMVSKLEHCLADLLFRWKMGELKMDIVGIVSNHPDFAPL--AAQHGLPFRHFPITA- 153 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 D++ + + + + ++V+LA +M++LSP + A R +NIH S LP + G + Sbjct: 154 DTKAQQEAQWLDVFETSGAELVILARYMQVLSPEASARLANRAINIHHSFLPGFKGAKPY 213 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQ 151 QA G + G + HFVTD+LD GP+I Q Sbjct: 214 HQAHARGVKLIGATAHFVTDDLDEGPIIEQ 243 >3OBI-A nrPDB Length = 288 Score = 67.0 bits (162), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 40/128 (31%), Positives = 64/128 (50%) Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 D+R + + I D+VVLA +M+ILS + AGR +NIH S LP + G + Sbjct: 149 DTRRQQEAAITALIAQTHTDLVVLARYMQILSDEMSARLAGRCINIHHSFLPGFKGAKPY 208 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA + G + G + H+VT LD GP+I Q + D+ D+ + + E + + Sbjct: 209 HQAFDRGVKLIGATAHYVTSALDEGPIIDQDVERISHRDTPADLVRKGRDIERRVLSRAL 268 Query: 182 SWFADGRL 189 + D R+ Sbjct: 269 HYHLDDRV 276 >3N0V-A nrPDB Length = 286 Score = 66.2 bits (160), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 89/193 (46%), Gaps = 3/193 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +V+++S L ++ + ++ V AV SN D LE + A Sbjct: 92 KVVIMVSKADHCLNDLLYRQRIGQLGMDVVAVVSNHPD---LEPLAHWHKIPYYHFALDP 148 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 + +R+++ I+ ++V+LA +M++LSP G +NIH SLLP + G + Sbjct: 149 KDKPGQERKVLQVIEETGAELVILARYMQVLSPELCRRLDGWAINIHHSLLPGFKGAKPY 208 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA G + G + H++ ++LD GP+I Q V +D+ A+ + E + Sbjct: 209 HQAYNKGVKMVGATAHYINNDLDEGPIIAQGVEVVDHSHYPEDLIAKGRDIECLTLARAV 268 Query: 182 SWFADGRLKMHEN 194 + + R+ ++ N Sbjct: 269 GYHIERRVFLNAN 281 >4XD0-A nrPDB Length = 417 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Query: 88 FMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGP 147 F +I+ P+ +H R+ NIH S LP Y G++T + N ++E G ++H + +D G Sbjct: 96 FDKIIHPSKFTH--NRIFNIHFSYLPAYKGMYTSAWPILNNEQESGVTLHKIDHGIDTGA 153 Query: 148 VILQAKVPV 156 +I Q K P+ Sbjct: 154 IIDQQKFPL 162 >5VYT-A nrPDB Length = 261 Score = 50.8 bits (120), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 46/84 (54%) Query: 78 YAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVH 137 +APD+++ + ++ F+ +N+HPSLLP Y G ++ + NG+ E G S H Sbjct: 79 FAPDMIISMHYRSLIPGRFLKLAKKGSVNLHPSLLPAYRGTNSVAWVIINGESETGFSYH 138 Query: 138 FVTDELDGGPVILQAKVPVFAGDS 161 + + D G ++LQ ++ V D+ Sbjct: 139 RMDENADTGAILLQERISVEETDT 162 >5UIL-A nrPDB Length = 405 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 2/81 (2%) Query: 88 FMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGP 147 F +I+ P+ +H L NIH S LPKY G++T + NG++ G ++H + +D G Sbjct: 83 FDKIVQPSKFNH--NELFNIHFSYLPKYKGMYTSAWPILNGEDTSGVTLHKIDHGIDTGA 140 Query: 148 VILQAKVPVFAGDSEDDITAR 168 +I Q ++ + ++ D+ + Sbjct: 141 IIAQKEIIIQPFETAKDLYEK 161 >5UAI-A nrPDB Length = 322 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 48/89 (53%) Query: 81 DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVT 140 D++V+ + IL A + +N H SLLP++ G ++A+E GD E G +V + Sbjct: 92 DLMVVVAYGLILPQAVLDIPRLGCINSHASLLPRWRGAAPIQRAVEAGDAESGVTVMQME 151 Query: 141 DELDGGPVILQAKVPVFAGDSEDDITARV 169 LD GP++L+ P+ A D+ + R+ Sbjct: 152 AGLDTGPMLLKVSTPISAADTGGSLHDRL 180 >4LY0-A nrPDB Length = 274 Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 36/65 (55%) Query: 101 AGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD 160 + RL NIH S LPKY G+ T + N + E G ++H + + +D G +I Q P+ D Sbjct: 91 SDRLFNIHFSALPKYKGVFTSITPILNNELESGVTLHRIDNGIDTGNIIDQHCFPIDIND 150 Query: 161 SEDDI 165 + D+ Sbjct: 151 TARDL 155 >3TQQ-A nrPDB Length = 314 Score = 46.6 bits (109), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 37/126 (29%), Positives = 65/126 (51%), Gaps = 7/126 (5%) Query: 44 ERARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGR 103 E ARQ I I F R+ ++E + I M A DV+V+ + IL ++ + Sbjct: 52 EIARQNEIP----IIQPFSLRDEVEQEKL--IAMNA-DVMVVVAYGLILPKKALNAFRLG 104 Query: 104 LLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSED 163 +N+H SLLP++ G ++A+ GD E G S+ + + LD G V+ ++ + + D+ Sbjct: 105 CVNVHASLLPRWRGAAPIQRAILAGDRETGISIMQMNEGLDTGDVLAKSACVISSEDTAA 164 Query: 164 DITARV 169 D+ R+ Sbjct: 165 DLHDRL 170 >4TT8-A nrPDB Length = 318 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 23/61 (37%), Positives = 35/61 (57%) Query: 108 HPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITA 167 HPSLLP++ G L +GD++ G +V + D LD GP++LQ + V D+ + I Sbjct: 106 HPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQRECDVEPNDNVNSIYK 165 Query: 168 R 168 R Sbjct: 166 R 166 >1FMT-A nrPDB Length = 314 Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 64 REAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQ 123 R +++L+ E+ DV+V+ + IL A + +N+H SLLP++ G ++ Sbjct: 69 RPQENQQLVAELQA---DVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQR 125 Query: 124 ALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDS 161 +L GD E G ++ + LD G ++ + P+ A D+ Sbjct: 126 SLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDT 163 >4IQF-A nrPDB Length = 317 Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 6/91 (6%) Query: 72 IHEIDMYA------PDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQAL 125 I E D Y PD++V A F +I+ + +N+H SLLP+ G A+ Sbjct: 69 IREKDEYEKVLALEPDLIVTAAFGQIVPNEILEAPKYGCINVHASLLPELRGGAPIHYAI 128 Query: 126 ENGDEEHGTSVHFVTDELDGGPVILQAKVPV 156 G E+ G ++ ++ ++LD G ++ Q +V + Sbjct: 129 MEGKEKTGITIMYMVEKLDAGDILTQVEVEI 159 >4WKG-A nrPDB Length = 660 Score = 43.1 bits (100), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 40/89 (44%) Query: 72 IHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEE 131 + I +PDV+ + ++ + N+H SLLPKY G L NG+ E Sbjct: 68 VERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETE 127 Query: 132 HGTSVHFVTDELDGGPVILQAKVPVFAGD 160 G ++H + D G ++ Q ++ + D Sbjct: 128 TGVTLHRMVKRADAGAIVAQLRIAIAPDD 156 >5J63-A nrPDB Length = 308 Score = 43.1 bits (100), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 4/94 (4%) Query: 72 IHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEE 131 + I +PDV+ + ++ + N+H SLLPKY G L NG+ E Sbjct: 70 VERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETE 129 Query: 132 HGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDI 165 G ++H + D G ++ Q ++ + + DDI Sbjct: 130 TGVTLHRMVKRADAGAIVAQLRIAI----APDDI 159 >5JNF-C nrPDB Length = 587 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 7/119 (5%) Query: 81 DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVT 140 D +V + IL VS + GR++N+HPSLLP G ++ + + G ++H + Sbjct: 48 DWIVSYAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWD-ETPKGVTIHLID 106 Query: 141 DELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI-SW--FADGRLKMHENAA 196 + +D G +++Q ++ FA ED + AI L I W GR+ + A Sbjct: 107 EHVDTGDILVQEEI-AFA--DEDTLLDCYNKANQAIEELFIREWENIVHGRIAPYRQTA 162 >5ES6-A nrPDB Length = 685 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 7/119 (5%) Query: 81 DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVT 140 D +V + IL VS + GR++N+HPSLLP G ++ + + G ++H + Sbjct: 46 DWIVSYAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWD-ETPKGVTIHLID 104 Query: 141 DELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI-SW--FADGRLKMHENAA 196 + +D G +++Q ++ FA ED + AI L I W GR+ + A Sbjct: 105 EHVDTGDILVQEEI-AFA--DEDTLLDCYNKANQAIEELFIREWENIVHGRIAPYRQTA 160 >5ES8-A nrPDB Length = 776 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 7/119 (5%) Query: 81 DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVT 140 D +V + IL VS + GR++N+HPSLLP G ++ + + G ++H + Sbjct: 46 DWIVSYAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWD-ETPKGVTIHLID 104 Query: 141 DELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI-SW--FADGRLKMHENAA 196 + +D G +++Q ++ FA ED + AI L I W GR+ + A Sbjct: 105 EHVDTGDILVQEEI-AFA--DEDTLLDCYNKANQAIEELFIREWENIVHGRIAPYRQTA 160 >2BW0-A nrPDB Length = 329 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 38/153 (24%), Positives = 66/153 (43%), Gaps = 8/153 (5%) Query: 21 CKTNKIKGTVRAVFS-----NKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEI 75 C K V VF+ KAD GLE A + G+ S + ++ +++ + Sbjct: 39 CHLRKEGHEVVGVFTVPDKDGKADPLGLE-AEKDGVPVFKY--SRWRAKGQALPDVVAKY 95 Query: 76 DMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTS 135 ++ VL + + +S + HPSLLP++ G L +GD++ G S Sbjct: 96 QALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFS 155 Query: 136 VHFVTDELDGGPVILQAKVPVFAGDSEDDITAR 168 + + D LD G ++LQ + V D+ + R Sbjct: 156 IFWADDGLDTGDLLLQKECEVLPDDTVSTLYNR 188 >5VYQ-A nrPDB Length = 255 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Query: 103 RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSE 162 R +N+HP P G ++ +G ++ G ++H + D+LD GP+I Q + + + DS Sbjct: 97 RCVNVHPGFNPYNRGWFPQVFSIIDG-QKVGVTIHEIDDQLDHGPIIAQRECAIESWDSS 155 Query: 163 DDITARVQTQEHAI 176 + AR+ E + Sbjct: 156 GSVYARLMDIEREL 169 >4NV1-C nrPDB Length = 243 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Query: 104 LLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSED 163 +NIHP L P G ++ N G ++H + +E+D G +I+Q +V V + ++ Sbjct: 90 CINIHPGLNPYNRGWFPQVFSIINK-LPIGATIHVMDEEIDHGDIIIQEEVEVNSFENSF 148 Query: 164 DITARVQTQEHAIYPLVISWFADGRL 189 D+ A+VQ +E ++ VI + + Sbjct: 149 DVYAKVQKKEVELFTKVIDDILNNKF 174 >1S3I-A nrPDB Length = 310 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 33/61 (54%) Query: 108 HPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITA 167 HPSLLP++ G L +GD++ G ++ + D LD G ++LQ + V D+ + Sbjct: 106 HPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECEVLPDDTVSTLYN 165 Query: 168 R 168 R Sbjct: 166 R 166 >3Q0I-A nrPDB Length = 318 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 43/81 (53%) Query: 81 DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVT 140 D++V+ + +L + +N+H S+LP++ G ++++ GD E G ++ + Sbjct: 87 DLMVVVAYGLLLPKVVLDTPKLGCINVHGSILPRWRGAAPIQRSIWAGDSETGVTIMQMD 146 Query: 141 DELDGGPVILQAKVPVFAGDS 161 LD G ++ A +P+ A D+ Sbjct: 147 VGLDTGDMLKIATLPIEASDT 167 >3R8X-A nrPDB Length = 318 Score = 36.2 bits (82), Expect = 0.011, Method: Compositional matrix adjust. Identities = 22/89 (24%), Positives = 44/89 (49%) Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 F + E H + D++V+ + IL A ++ +N+H SLLP++ G Sbjct: 67 FQPKSLRPEENQHLVADLNADIMVVVAYGLILPAAVLAMPRLGCINVHGSLLPRWRGAAP 126 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVI 149 ++++ GDE+ G ++ + LD G ++ Sbjct: 127 IQRSVWAGDEKTGITIMQMDIGLDTGAML 155 >1VMI-A nrPDB Length = 355 Score = 34.7 bits (78), Expect = 0.028, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 3/55 (5%) Query: 14 LQAIIDACKTNKIKGTVRAVFSNKADAFGLERAR---QAGIATHTLIASAFDSRE 65 L+AII+ C+ ++ R VF + D L+ A+ Q G+AT L+A+ F+ R+ Sbjct: 11 LRAIIERCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPILVANPFELRQ 65 >4YFV-A nrPDB Length = 254 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 7/102 (6%) Query: 74 EIDMYAPDVVVLAGFMRILS----PAFVSHYAGRLL--NIHPSLLPKYPGLHTHRQALEN 127 EID+ ++ L + I+S F +H L NIHP L P G ++ N Sbjct: 54 EIDIKNKNLNELNDYHLIISAHCKQIFPAHIVNNKLCINIHPGLNPYNRGWFPQVFSILN 113 Query: 128 GDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARV 169 + G ++H + E+D G + Q +V + + ++ DI +V Sbjct: 114 K-KPIGATIHKMDSEVDHGEIYCQEEVSILSHETSIDIYNKV 154 >6NBP-A nrPDB Length = 263 Score = 30.8 bits (68), Expect = 0.50, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%) Query: 104 LLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSED 163 +N HP L P G + ++ NG G ++H + E+D G +I Q +V V D+ Sbjct: 110 CINFHPGLNPYNRGWYPQAFSIING-LPTGATIHLMDAEVDHGDIIDQQEVEVKMSDTSL 168 Query: 164 DITARV 169 + +V Sbjct: 169 TVYRKV 174 >4NAV-D nrPDB Length = 182 Score = 26.9 bits (58), Expect = 7.0, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 3/62 (4%) Query: 117 GLHTHRQALENGDEEHGTS---VHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQE 173 G+ R A+ +EHG S V F+ D+L P +L +PV ++ I RVQ Sbjct: 91 GVKNKRLAVLALCQEHGLSLDQVLFMGDDLPDLPALLAVGLPVAPANAHPWIAERVQWHT 150 Query: 174 HA 175 A Sbjct: 151 RA 152 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1JKX-A nrPDB 287 2e-78 3TQR-A nrPDB 263 5e-71 3AUF-A nrPDB 246 8e-66 1MEJ-B nrPDB 241 2e-64 2YWR-A nrPDB 237 3e-63 3AV3-A nrPDB 232 6e-62 4DS3-A nrPDB 227 4e-60 3P9X-A nrPDB 226 6e-60 3KCQ-A nrPDB 224 2e-59 3O1L-A nrPDB 212 6e-56 4S1N-A nrPDB 209 5e-55 3W7B-A nrPDB 208 1e-54 3N0V-A nrPDB 206 5e-54 3NRB-A nrPDB 199 6e-52 3OBI-A nrPDB 196 9e-51 3LOU-A nrPDB 193 4e-50 5CJJ-A nrPDB 191 1e-49 3DA8-A nrPDB 189 7e-49 2BW0-A nrPDB 160 3e-40 1S3I-A nrPDB 160 3e-40 4TT8-A nrPDB 146 7e-36 1FMT-A nrPDB 138 1e-33 3TQQ-A nrPDB 135 1e-32 4IQF-A nrPDB 133 3e-32 4WKG-A nrPDB 128 2e-30 5J63-A nrPDB 126 9e-30 5JNF-C nrPDB 124 3e-29 5ES6-A nrPDB 123 5e-29 5ES8-A nrPDB 123 6e-29 5UAI-A nrPDB 116 9e-27 5VYT-A nrPDB 112 1e-25 4XD0-A nrPDB 106 8e-24 5UIL-A nrPDB 105 1e-23 5VYQ-A nrPDB 104 2e-23 4NV1-C nrPDB 104 3e-23 4LY0-A nrPDB 96 1e-20 Sequences not found previously or not previously below threshold: 3R8X-A nrPDB 127 4e-30 3Q0I-A nrPDB 119 8e-28 6CI4-A nrPDB 104 3e-23 6CI2-A nrPDB 104 3e-23 6NBP-A nrPDB 98 3e-21 4YFV-A nrPDB 97 7e-21 6CUL-A nrPDB 53 1e-07 1ZGH-A nrPDB 53 1e-07 3FXA-A nrPDB 31 0.46 4ZMS-A nrPDB 30 1.1 1VKY-A nrPDB 30 1.1 4E7O-A nrPDB 29 1.4 3CXM-A nrPDB 29 1.5 1D7K-A nrPDB 29 1.7 1RT8-A nrPDB 28 3.4 7ODC-A nrPDB 28 3.9 1M32-A nrPDB 27 6.3 2YXZ-A nrPDB 27 7.1 >1JKX-A nrPDB Length = 212 Score = 287 bits (735), Expect = 2e-78, Method: Composition-based stats. Identities = 212/212 (100%), Positives = 212/212 (100%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA Sbjct: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT Sbjct: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV Sbjct: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 Query: 181 ISWFADGRLKMHENAAWLDGQRLPPQGYAADE 212 ISWFADGRLKMHENAAWLDGQRLPPQGYAADE Sbjct: 181 ISWFADGRLKMHENAAWLDGQRLPPQGYAADE 212 >3TQR-A nrPDB Length = 215 Score = 263 bits (672), Expect = 5e-71, Method: Composition-based stats. Identities = 113/209 (54%), Positives = 147/209 (70%), Gaps = 1/209 (0%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + IVVLISGNG+NLQAII A + + +RAV SN+ADA+GL+RA+QA I TH + Sbjct: 6 LPIVVLISGNGTNLQAIIGAIQKG-LAIEIRAVISNRADAYGLKRAQQADIPTHIIPHEE 64 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 F SR ++ L ID Y P ++VLAGFMR L AFVSHY+GR++NIHPSLLPKY GL+T Sbjct: 65 FPSRTDFESTLQKTIDHYDPKLIVLAGFMRKLGKAFVSHYSGRMINIHPSLLPKYTGLNT 124 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 H +AL G+ EHG SVH+VT++LD GP+I QA++ + D+ + + RV EH IYP V Sbjct: 125 HERALAAGETEHGVSVHYVTEDLDAGPLICQARLSITPQDTPETLKTRVHALEHIIYPEV 184 Query: 181 ISWFADGRLKMHENAAWLDGQRLPPQGYA 209 +SWFA GRL H N +LDG+ L G+A Sbjct: 185 LSWFAAGRLNYHNNQVFLDGKPLAKSGHA 213 >3AUF-A nrPDB Length = 229 Score = 246 bits (627), Expect = 8e-66, Method: Composition-based stats. Identities = 96/207 (46%), Positives = 136/207 (65%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + I VLISG+G+NLQAI+D C+ +I G V V S++ADA+GLERAR+AG+ + +A Sbjct: 23 IRIGVLISGSGTNLQAILDGCREGRIPGRVAVVISDRADAYGLERARRAGVDALHMDPAA 82 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 + SR A+D L + Y D+V LAG+MR++ ++ + R+LNIHPSLLP +PGL Sbjct: 83 YPSRTAFDAALAERLQAYGVDLVCLAGYMRLVRGPMLTAFPNRILNIHPSLLPAFPGLEA 142 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 RQALE+G + G +VHFVT +D GP+ILQA VPV GD+ +D+ R+ +EH IYP Sbjct: 143 QRQALEHGVKVAGCTVHFVTAGVDEGPIILQAAVPVLEGDTVEDLRRRILAEEHRIYPEA 202 Query: 181 ISWFADGRLKMHENAAWLDGQRLPPQG 207 I FA+GRL + + + P+G Sbjct: 203 IRLFAEGRLVIEGRRVRILDRAEAPRG 229 >1MEJ-B nrPDB Length = 223 Score = 241 bits (614), Expect = 2e-64, Method: Composition-based stats. Identities = 84/203 (41%), Positives = 123/203 (60%), Gaps = 2/203 (0%) Query: 3 IVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFD 62 + VLISG GSNLQA+ID+ + + V SNKA GL++A +AGI T + + Sbjct: 14 VAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYK 73 Query: 63 SREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHR 122 +R +D + ++ ++ D+V LAGFMRILS FV + G++LNIHPSLLP + G + H Sbjct: 74 NRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAHE 133 Query: 123 QALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVIS 182 QALE G G +VHFV +++D G +ILQ VPV GD+ ++ RV+ EH I+P + Sbjct: 134 QALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAALQ 193 Query: 183 WFADGRLKMHENA--AWLDGQRL 203 A G +++ EN W+ + L Sbjct: 194 LVASGTVQLGENGKICWVKEEPL 216 >2YWR-A nrPDB Length = 216 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 75/199 (37%), Positives = 119/199 (59%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + I VL+SG GSNLQAIIDA ++ K+ ++ V S+ A+ +ER ++ + + Sbjct: 2 LKIGVLVSGRGSNLQAIIDAIESGKVNASIELVISDNPKAYAIERCKKHNVECKVIQRKE 61 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 F S++ ++ + E+ ++VVLAGFMRILS F+ ++ +++NIHPSL+P + GLH Sbjct: 62 FPSKKEFEERMALELKKKGVELVVLAGFMRILSHNFLKYFPNKVINIHPSLIPAFQGLHA 121 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 +QA+E G + G +VH V + +D GPVI+QA VPV D E+ + R+ EH I P Sbjct: 122 QKQAVEFGVKFSGCTVHIVDESVDAGPVIVQAVVPVLPEDDENTLADRILKWEHKILPQT 181 Query: 181 ISWFADGRLKMHENAAWLD 199 + WFA R+ + + Sbjct: 182 VQWFAQDRIIIDGRKVIVK 200 >3AV3-A nrPDB Length = 212 Score = 232 bits (593), Expect = 6e-62, Method: Composition-based stats. Identities = 64/193 (33%), Positives = 104/193 (53%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 + V SG+G+N QAI+DA K + V + ++ A +ERA + + + Sbjct: 5 RLAVFASGSGTNFQAIVDAAKRGDLPARVALLVCDRPGAKVIERAARENVPAFVFSPKDY 64 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 S+ A++ E++ E+ D + LAG+MR++ P +S Y G+++NIHPSLLP +PG Sbjct: 65 PSKAAFESEILRELKGRQIDWIALAGYMRLIGPTLLSAYEGKIVNIHPSLLPAFPGKDAI 124 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA G E G +VH+V + +D GPVI Q VP+ G+ + + R+ EH +YP V+ Sbjct: 125 GQAYRAGVSETGVTVHYVDEGMDTGPVIAQRVVPIVPGEPIEALEERIHQVEHELYPTVL 184 Query: 182 SWFADGRLKMHEN 194 + + E Sbjct: 185 RMLLGEKEQQEER 197 >4DS3-A nrPDB Length = 209 Score = 227 bits (578), Expect = 4e-60, Method: Composition-based stats. Identities = 87/186 (46%), Positives = 126/186 (67%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +V+ ISG GSN++A+I A + + AVFS+KA+A GL +A AGIAT F Sbjct: 9 RVVIFISGGGSNMEALIRAAQAPGFPAEIVAVFSDKAEAGGLAKAEAAGIATQVFKRKDF 68 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 S+EA++ ++ +D+ PD++ LAG+MR+LS F++ Y GR+LNIHPSLLP +PGLHTH Sbjct: 69 ASKEAHEDAILAALDVLKPDIICLAGYMRLLSGRFIAPYEGRILNIHPSLLPLFPGLHTH 128 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 ++AL+ G + G +VH VT+ +D GP++ QA VPV GD+ + + ARV EH +YPL + Sbjct: 129 QRALDAGMKLAGCTVHLVTEGMDEGPILAQAAVPVLDGDTAETLAARVLKAEHRLYPLAL 188 Query: 182 SWFADG 187 FA G Sbjct: 189 QKFAAG 194 >3P9X-A nrPDB Length = 211 Score = 226 bits (576), Expect = 6e-60, Method: Composition-based stats. Identities = 62/191 (32%), Positives = 107/191 (56%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 + + SG+G+N +AII + K ++ V + ++K A +ER + I L + Sbjct: 4 RVAIFASGSGTNAEAIIQSQKAGQLPCEVALLITDKPGAKVVERVKVHEIPVCALDPKTY 63 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 S+EAY+ E++ ++ D VVLAG+MR++ P + Y GR++NIHPSLLP +PGLH Sbjct: 64 PSKEAYEIEVVQQLKEKQIDFVVLAGYMRLVGPTLLGAYEGRIVNIHPSLLPAFPGLHAI 123 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA+ + G ++H+V + +D GP+I Q V + D+ + +T ++Q EH +YP + Sbjct: 124 EQAIRANVKVTGVTIHYVDEGMDTGPIIAQEAVSIEEEDTLETLTTKIQAVEHRLYPATL 183 Query: 182 SWFADGRLKMH 192 ++ Sbjct: 184 HKLLSKAENLY 194 >3KCQ-A nrPDB Length = 215 Score = 224 bits (572), Expect = 2e-59, Method: Composition-based stats. Identities = 70/195 (35%), Positives = 108/195 (55%), Gaps = 5/195 (2%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60 + + VLISG GSNL+A+ A T + + V SN A+A GL A+ GI T + Sbjct: 9 LRVGVLISGRGSNLEALAKAFSTEESSVVISCVISNNAEARGLLIAQSYGIPTFVVKRKP 68 Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 D + + + D+V LAGFM IL FV+ + +++NIHPSLLP + GL+ Sbjct: 69 LDIEH-----ISTVLREHDVDLVCLAGFMSILPEKFVTDWHHKIINIHPSLLPSFKGLNA 123 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180 QA + G + G ++H+V ELD GP+I+QA VPV D+ + + +R+ EH YP Sbjct: 124 QEQAYKAGVKIAGCTLHYVYQELDAGPIIMQAAVPVLREDTAESLASRILAAEHVCYPKG 183 Query: 181 ISWFADGRLKMHENA 195 + A ++K+ ++ Sbjct: 184 VKLIAQDKIKLCDDG 198 >3O1L-A nrPDB Length = 302 Score = 212 bits (541), Expect = 6e-56, Method: Composition-based stats. Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 3/193 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +V++ S L ++ ++++ + V SN D + I + + Sbjct: 107 RVVLMASRESHCLADLLHRWHSDELDCDIACVISNHQDLRSM--VEWHDIPYYHVPVDPK 164 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 D A+ E+ + + DVVVLA +M+IL P YA +++NIH S LP + G + Sbjct: 165 DKEPAF-AEVSRLVGHHQADVVVLARYMQILPPQLCREYAHQVINIHHSFLPSFVGAKPY 223 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA G + G + H+VT+ELD GP+I Q V V DS +++ + E + + Sbjct: 224 HQASLRGVKLIGATCHYVTEELDAGPIIEQDVVRVSHRDSIENMVRFGRDVEKMVLARGL 283 Query: 182 SWFADGRLKMHEN 194 + R+ +H+N Sbjct: 284 RAHLEDRVLVHDN 296 >4S1N-A nrPDB Length = 184 Score = 209 bits (533), Expect = 5e-55, Method: Composition-based stats. Identities = 68/186 (36%), Positives = 104/186 (55%), Gaps = 7/186 (3%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 I V SGNGSN Q I + + V VFS+ DA+ LERA+Q G+ ++ F Sbjct: 6 KIAVFASGNGSNFQVIAE-------EFPVEFVFSDHRDAYVLERAKQLGVLSYAFELKEF 58 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 +S+ Y+ L+ ++ + D+V LAG+M+I+ P +S Y GR++NIHP+ LP++PG H Sbjct: 59 ESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIHPAYLPEFPGAHGI 118 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 A G + G ++H+V +D G VI Q +VP A D+ D AR+ E+ +YP V+ Sbjct: 119 EDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFEARIHEAEYRLYPEVV 178 Query: 182 SWFADG 187 Sbjct: 179 KALFTD 184 >3W7B-A nrPDB Length = 285 Score = 208 bits (529), Expect = 1e-54, Method: Composition-based stats. Identities = 57/193 (29%), Positives = 95/193 (49%), Gaps = 3/193 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +L+S L ++ + ++ +R V SN D E + GI H + Sbjct: 90 RTAILVSKPAHALLELLWRYRVGELPMELRLVISNHPD--HREEVERFGIPYHHVPVEKG 147 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 +E + ++ ++ ++VVLA +M+ILSP FV + R++NIH S LP + G + Sbjct: 148 R-KEEAEERILALLEAEGVELVVLARYMQILSPGFVERFPMRIINIHHSFLPAFAGADPY 206 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 RQA E G + G + H+VT+ELD GP+I Q V V S ++ + E + + Sbjct: 207 RQAYERGVKLIGATAHYVTEELDQGPIIEQDVVRVSHRHSVREMKRLGRELERTVLARAV 266 Query: 182 SWFADGRLKMHEN 194 W + R+ +HEN Sbjct: 267 RWHLEDRILVHEN 279 >3N0V-A nrPDB Length = 286 Score = 206 bits (525), Expect = 5e-54, Method: Composition-based stats. Identities = 48/193 (24%), Positives = 90/193 (46%), Gaps = 3/193 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +V+++S L ++ + ++ V AV SN D L A I + Sbjct: 92 KVVIMVSKADHCLNDLLYRQRIGQLGMDVVAVVSNHPDLEPL--AHWHKIPYYHFALDPK 149 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 D + +R+++ I+ ++V+LA +M++LSP G +NIH SLLP + G + Sbjct: 150 D-KPGQERKVLQVIEETGAELVILARYMQVLSPELCRRLDGWAINIHHSLLPGFKGAKPY 208 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA G + G + H++ ++LD GP+I Q V +D+ A+ + E + Sbjct: 209 HQAYNKGVKMVGATAHYINNDLDEGPIIAQGVEVVDHSHYPEDLIAKGRDIECLTLARAV 268 Query: 182 SWFADGRLKMHEN 194 + + R+ ++ N Sbjct: 269 GYHIERRVFLNAN 281 >3NRB-A nrPDB Length = 287 Score = 199 bits (507), Expect = 6e-52, Method: Composition-based stats. Identities = 50/191 (26%), Positives = 91/191 (47%), Gaps = 2/191 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +V+++S L ++ + ++ V + SN L + I H L + Sbjct: 90 KVVIMVSKFDHCLGDLLYRHRLGELDMEVVGIISNHPR-EALSVSLVGDIPFHYLPVTP- 147 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 ++ A + ++ + + D++VLA +M+ILS + +GR +NIH S LP + G + Sbjct: 148 ATKAAQESQIKNIVTQSQADLIVLARYMQILSDDLSAFLSGRCINIHHSFLPGFKGAKPY 207 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA G + G + HFVT +LD GP+I Q V DS +D+ + + E + + Sbjct: 208 HQAHTRGVKLIGATAHFVTADLDEGPIIAQDVEHVSHRDSAEDLVRKGRDIERRVLSRAV 267 Query: 182 SWFADGRLKMH 192 F + RL ++ Sbjct: 268 LLFLEDRLIVN 278 >3OBI-A nrPDB Length = 288 Score = 196 bits (497), Expect = 9e-51, Method: Composition-based stats. Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 6/193 (3%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKAD--AFGLERARQAGIATHTLIAS 59 +++L+S + L I+ + + A+ SN G + I + + Sbjct: 91 KVMLLVSQSDHCLADILYRWRVGDLHMIPTAIVSNHPRETFSGFDFG---DIPFYHFPVN 147 Query: 60 AFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLH 119 D+R + + I D+VVLA +M+ILS + AGR +NIH S LP + G Sbjct: 148 K-DTRRQQEAAITALIAQTHTDLVVLARYMQILSDEMSARLAGRCINIHHSFLPGFKGAK 206 Query: 120 THRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPL 179 + QA + G + G + H+VT LD GP+I Q + D+ D+ + + E + Sbjct: 207 PYHQAFDRGVKLIGATAHYVTSALDEGPIIDQDVERISHRDTPADLVRKGRDIERRVLSR 266 Query: 180 VISWFADGRLKMH 192 + + D R+ ++ Sbjct: 267 ALHYHLDDRVILN 279 >3LOU-A nrPDB Length = 292 Score = 193 bits (491), Expect = 4e-50, Method: Composition-based stats. Identities = 49/193 (25%), Positives = 91/193 (47%), Gaps = 3/193 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +++++S L ++ K ++K + + SN D L A Q G+ +A Sbjct: 97 KVLIMVSKLEHCLADLLFRWKMGELKMDIVGIVSNHPDFAPL--AAQHGLPFRHFPITA- 153 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 D++ + + + + ++V+LA +M++LSP + A R +NIH S LP + G + Sbjct: 154 DTKAQQEAQWLDVFETSGAELVILARYMQVLSPEASARLANRAINIHHSFLPGFKGAKPY 213 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 QA G + G + HFVTD+LD GP+I Q V + + A + E + Sbjct: 214 HQAHARGVKLIGATAHFVTDDLDEGPIIEQVVERVDHSYRPEQLLAVGRDVECITLARAV 273 Query: 182 SWFADGRLKMHEN 194 F + R+ ++ + Sbjct: 274 KAFIERRVFLNGD 286 >5CJJ-A nrPDB Length = 191 Score = 191 bits (486), Expect = 1e-49, Method: Composition-based stats. Identities = 70/189 (37%), Positives = 110/189 (58%), Gaps = 7/189 (3%) Query: 1 MNIVVLISGNGSNLQAIIDACKTNKIK---GTVRAVFSNKADAFGLERARQAGIATHTLI 57 + + VL SGNGSNL+ I++ I + NK DAFG++RA++ G+ T + Sbjct: 6 VKLAVLFSGNGSNLENILEKLHKKTIGENTYEIVLCLCNKKDAFGIQRAKKFGLNTVIID 65 Query: 58 ASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPG 117 A+++RE +D L+ +I ++ VLAGFMRILSP F + + +N+HPSLLP + G Sbjct: 66 HKAYNTREEFDTILVQKIKESGANLTVLAGFMRILSPVFTKNI--KAINLHPSLLPLFKG 123 Query: 118 LHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIY 177 H +++ E+ + G SVH+V++ELDGG +I Q S ++ ++ + EH I Sbjct: 124 AHAIKESYESDMKVAGVSVHWVSEELDGGMIIAQKAFE-KRNLSFEEFEEKIHSLEHEIL 182 Query: 178 PL-VISWFA 185 PL VI F+ Sbjct: 183 PLSVIEIFS 191 >3DA8-A nrPDB Length = 215 Score = 189 bits (480), Expect = 7e-49, Method: Composition-based stats. Identities = 66/174 (37%), Positives = 95/174 (54%), Gaps = 2/174 (1%) Query: 2 NIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAF 61 +VVL SG GS L++++DA V AV ++ + E A +A + T+ + Sbjct: 14 RLVVLASGTGSLLRSLLDAA-VGDYPARVVAVGVDR-ECRAAEIAAEASVPVFTVRLADH 71 Query: 62 DSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTH 121 SR+A+D + + PD+VV AGFMRIL P F+S + GR LN HP+LLP +PG H Sbjct: 72 PSRDAWDVAITAATAAHEPDLVVSAGFMRILGPQFLSRFYGRTLNTHPALLPAFPGTHGV 131 Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHA 175 AL G + G +VH V D GP++ Q VPV GD E+ + R++ E Sbjct: 132 ADALAYGVKVTGATVHLVDAGTDTGPILAQQPVPVLDGDDEETLHERIKVTERR 185 >2BW0-A nrPDB Length = 329 Score = 160 bits (406), Expect = 3e-40, Method: Composition-based stats. Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 9/174 (5%) Query: 21 CKTNKIKGTVRAVFS-----NKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEI 75 C K V VF+ KAD GLE A + G+ S + ++ +++ + Sbjct: 39 CHLRKEGHEVVGVFTVPDKDGKADPLGLE-AEKDGVPVFKY--SRWRAKGQALPDVVAKY 95 Query: 76 DMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTS 135 ++ VL + + +S + HPSLLP++ G L +GD++ G S Sbjct: 96 QALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFS 155 Query: 136 VHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQE-HAIYPLVISWFADGR 188 + + D LD G ++LQ + V D+ + R E + A+G+ Sbjct: 156 IFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGK 209 >1S3I-A nrPDB Length = 310 Score = 160 bits (406), Expect = 3e-40, Method: Composition-based stats. Identities = 40/174 (22%), Positives = 71/174 (40%), Gaps = 9/174 (5%) Query: 21 CKTNKIKGTVRAVFS-----NKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEI 75 C+ K V VF+ KAD GLE A + G+ + +R E++ + Sbjct: 17 CQLRKEGHEVVGVFTIPDKDGKADPDGLE-AEKDGVPVFKFPR--WRARGQALPEVVAKY 73 Query: 76 DMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTS 135 ++ VL + + ++ + HPSLLP++ G L +GD++ G + Sbjct: 74 QALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFT 133 Query: 136 VHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQE-HAIYPLVISWFADGR 188 + + D LD G ++LQ + V D+ + R E + A+G Sbjct: 134 IFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGT 187 >4TT8-A nrPDB Length = 318 Score = 146 bits (368), Expect = 7e-36, Method: Composition-based stats. Identities = 41/184 (22%), Positives = 72/184 (39%), Gaps = 12/184 (6%) Query: 22 KTNKIKGTVRAVFS-----NKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEID 76 + + VF+ K D +E A + G+ + + E++ + Sbjct: 18 ELKNEGHMIVGVFTIPDKDGKVDPLAIE-AEKDGVPVFKFPR--WRLKGKAITEVVDQYK 74 Query: 77 MYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSV 136 ++ VL + + + H + HPSLLP++ G L +GD++ G +V Sbjct: 75 AVGAELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTV 134 Query: 137 HFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQE-HAIYPLVISWFADG---RLKMH 192 + D LD GP++LQ + V D+ + I R E + A G R+K Sbjct: 135 FWADDGLDTGPILLQRECDVEPNDNVNSIYKRFLFPEGVKGMVEAVRLIATGKAPRIKQP 194 Query: 193 ENAA 196 E A Sbjct: 195 EEGA 198 >1FMT-A nrPDB Length = 314 Score = 138 bits (349), Expect = 1e-33, Method: Composition-based stats. Identities = 37/177 (20%), Positives = 71/177 (40%), Gaps = 17/177 (9%) Query: 26 IKGTVRAVFS--NKADAFGLER--------ARQAGIATHTLIASAFDSREAYDRELIHEI 75 V VF+ ++ G + A + G+ R +++L+ E+ Sbjct: 25 SGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVF----QPVSLRPQENQQLVAEL 80 Query: 76 DMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTS 135 DV+V+ + IL A + +N+H SLLP++ G +++L GD E G + Sbjct: 81 Q---ADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVT 137 Query: 136 VHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMH 192 + + LD G ++ + P+ A D+ + ++ + ADG K Sbjct: 138 IMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPE 194 >3TQQ-A nrPDB Length = 314 Score = 135 bits (340), Expect = 1e-32, Method: Composition-based stats. Identities = 44/191 (23%), Positives = 86/191 (45%), Gaps = 23/191 (12%) Query: 14 LQAIIDACKTNKIKGTVRAVFS--NKADAFGL--------ERARQAGIATHTLIASAFDS 63 L+A+ID+ V AV++ ++ G E ARQ I I F Sbjct: 18 LRALIDSSH------RVLAVYTQPDRPSGRGQKIMESPVKEIARQNEIP----IIQPFSL 67 Query: 64 REAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQ 123 R+ ++E ++ DV+V+ + IL ++ + +N+H SLLP++ G ++ Sbjct: 68 RDEVEQE---KLIAMNADVMVVVAYGLILPKKALNAFRLGCVNVHASLLPRWRGAAPIQR 124 Query: 124 ALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISW 183 A+ GD E G S+ + + LD G V+ ++ + + D+ D+ R+ + ++ Sbjct: 125 AILAGDRETGISIMQMNEGLDTGDVLAKSACVISSEDTAADLHDRLSLIGADLLLESLAK 184 Query: 184 FADGRLKMHEN 194 G +K+ + Sbjct: 185 LEKGDIKLEKQ 195 >4IQF-A nrPDB Length = 317 Score = 133 bits (336), Expect = 3e-32, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 64/147 (43%), Gaps = 7/147 (4%) Query: 45 RARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRL 104 A + GI L ++ Y++ L PD++V A F +I+ + Sbjct: 55 EAEKHGIP--VLQPLRIREKDEYEKVL-----ALEPDLIVTAAFGQIVPNEILEAPKYGC 107 Query: 105 LNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDD 164 +N+H SLLP+ G A+ G E+ G ++ ++ ++LD G ++ Q +V + ++ Sbjct: 108 INVHASLLPELRGGAPIHYAIMEGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGS 167 Query: 165 ITARVQTQEHAIYPLVISWFADGRLKM 191 + ++ + + G+L+ Sbjct: 168 LFDKLSEAGAHLLSKTVPLLIQGKLEP 194 >4WKG-A nrPDB Length = 660 Score = 128 bits (321), Expect = 2e-30, Method: Composition-based stats. Identities = 41/216 (18%), Positives = 75/216 (34%), Gaps = 25/216 (11%) Query: 1 MNIVVLISGNGSNL--QAIIDACKTNKIKGTVRAVFS--NKADAFGL-----ERARQAGI 51 M VV + L +A++ A + A+F+ + A + GI Sbjct: 1 MKTVVFAYHDMGCLGIEALLAA------GYEISAIFTHTDNPGEKAFYGSVARLAAERGI 54 Query: 52 ATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSL 111 + + I +PDV+ + ++ + N+H SL Sbjct: 55 PVYAPDNVNHPL-------WVERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFNLHGSL 107 Query: 112 LPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQT 171 LPKY G L NG+ E G ++H + D G ++ Q ++ + D + ++ Sbjct: 108 LPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCH 167 Query: 172 QEHAIYPLVISWFADG---RLKMHENAAWLDGQRLP 204 + + G + EN A G+R P Sbjct: 168 AARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTP 203 >3R8X-A nrPDB Length = 318 Score = 127 bits (319), Expect = 4e-30, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 65/155 (41%), Gaps = 17/155 (10%) Query: 28 GTVRAVFS--NKADAFGLER--------ARQAGIATHTLIASAFDSREAYDRELIHEIDM 77 + VF+ ++ G + A GI R ++ L+ ++ Sbjct: 31 HKIVGVFTQPDRPAGRGNKLTPSPVKILAEHHGIPVF----QPKSLRPEENQHLVADL-- 84 Query: 78 YAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVH 137 D++V+ + IL A ++ +N+H SLLP++ G ++++ GDE+ G ++ Sbjct: 85 -NADIMVVVAYGLILPAAVLAMPRLGCINVHGSLLPRWRGAAPIQRSVWAGDEKTGITIM 143 Query: 138 FVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQ 172 + LD G ++ + + + D+ + ++ Sbjct: 144 QMDIGLDTGAMLHKIECAIQPEDTSATLYDKLAQL 178 >5J63-A nrPDB Length = 308 Score = 126 bits (316), Expect = 9e-30, Method: Composition-based stats. Identities = 41/216 (18%), Positives = 75/216 (34%), Gaps = 25/216 (11%) Query: 1 MNIVVLISGNGSNL--QAIIDACKTNKIKGTVRAVFS--NKADAFGL-----ERARQAGI 51 M VV + L +A++ A + A+F+ + A + GI Sbjct: 3 MKTVVFAYHDMGCLGIEALLAA------GYEISAIFTHTDNPGEKAFYGSVARLAAERGI 56 Query: 52 ATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSL 111 + + I +PDV+ + ++ + N+H SL Sbjct: 57 PVYAPDNVNHPL-------WVERIAQLSPDVIFSFYYRHLIYDEILQLAPAGAFNLHGSL 109 Query: 112 LPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQT 171 LPKY G L NG+ E G ++H + D G ++ Q ++ + D + ++ Sbjct: 110 LPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCH 169 Query: 172 QEHAIYPLVISWFADG---RLKMHENAAWLDGQRLP 204 + + G + EN A G+R P Sbjct: 170 AARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTP 205 >5JNF-C nrPDB Length = 587 Score = 124 bits (311), Expect = 3e-29, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 1/118 (0%) Query: 79 APDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHF 138 D +V + IL VS + GR++N+HPSLLP G ++ + + G ++H Sbjct: 46 EIDWIVSYAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWD-ETPKGVTIHL 104 Query: 139 VTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHENAA 196 + + +D G +++Q ++ D+ D + ++ GR+ + A Sbjct: 105 IDEHVDTGDILVQEEIAFADEDTLLDCYNKANQAIEELFIREWENIVHGRIAPYRQTA 162 >5ES6-A nrPDB Length = 685 Score = 123 bits (309), Expect = 5e-29, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 1/118 (0%) Query: 79 APDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHF 138 D +V + IL VS + GR++N+HPSLLP G ++ + + G ++H Sbjct: 44 EIDWIVSYAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWD-ETPKGVTIHL 102 Query: 139 VTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHENAA 196 + + +D G +++Q ++ D+ D + ++ GR+ + A Sbjct: 103 IDEHVDTGDILVQEEIAFADEDTLLDCYNKANQAIEELFIREWENIVHGRIAPYRQTA 160 >5ES8-A nrPDB Length = 776 Score = 123 bits (308), Expect = 6e-29, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 1/118 (0%) Query: 79 APDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHF 138 D +V + IL VS + GR++N+HPSLLP G ++ + + G ++H Sbjct: 44 EIDWIVSYAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWD-ETPKGVTIHL 102 Query: 139 VTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHENAA 196 + + +D G +++Q ++ D+ D + ++ GR+ + A Sbjct: 103 IDEHVDTGDILVQEEIAFADEDTLLDCYNKANQAIEELFIREWENIVHGRIAPYRQTA 160 >3Q0I-A nrPDB Length = 318 Score = 119 bits (299), Expect = 8e-28, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 59/143 (41%), Gaps = 7/143 (4%) Query: 46 ARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLL 105 A + + + F S E+ ++ D++V+ + +L + + Sbjct: 59 ALEHNVPVY--QPENFKSDES-----KQQLAALNADLMVVVAYGLLLPKVVLDTPKLGCI 111 Query: 106 NIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDI 165 N+H S+LP++ G ++++ GD E G ++ + LD G ++ A +P+ A D+ + Sbjct: 112 NVHGSILPRWRGAAPIQRSIWAGDSETGVTIMQMDVGLDTGDMLKIATLPIEASDTSASM 171 Query: 166 TARVQTQEHAIYPLVISWFADGR 188 ++ + A G Sbjct: 172 YDKLAELGPQALLECLQDIAQGT 194 >5UAI-A nrPDB Length = 322 Score = 116 bits (290), Expect = 9e-27, Method: Composition-based stats. Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 23/186 (12%) Query: 14 LQAIIDACKTNKIKGTVRAVFS--NKADAFGLER--------ARQAGIATHTLIASAFDS 63 L+A++D + AV++ ++ G + A + G+ + + + Sbjct: 28 LKALLDT------PHRIVAVYTQPDRPAGRGQKLMPSAVKSLALEHGLP--VMQPQSLRN 79 Query: 64 REAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQ 123 EA D++V+ + IL A + +N H SLLP++ G ++ Sbjct: 80 AEAQAELAALR-----ADLMVVVAYGLILPQAVLDIPRLGCINSHASLLPRWRGAAPIQR 134 Query: 124 ALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISW 183 A+E GD E G +V + LD GP++L+ P+ A D+ + R+ I+ Sbjct: 135 AVEAGDAESGVTVMQMEAGLDTGPMLLKVSTPISAADTGGSLHDRLAALGPKAVIEAIAG 194 Query: 184 FADGRL 189 A G L Sbjct: 195 LAAGTL 200 >5VYT-A nrPDB Length = 261 Score = 112 bits (280), Expect = 1e-25, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 52/108 (48%) Query: 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120 F + A E +APD+++ + ++ F+ +N+HPSLLP Y G ++ Sbjct: 62 FTTAAANSEEFYEFGANFAPDMIISMHYRSLIPGRFLKLAKKGSVNLHPSLLPAYRGTNS 121 Query: 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITAR 168 + NG+ E G S H + + D G ++LQ ++ V D+ + R Sbjct: 122 VAWVIINGESETGFSYHRMDENADTGAILLQERISVEETDTAFSLFHR 169 >4XD0-A nrPDB Length = 417 Score = 106 bits (264), Expect = 8e-24, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 64/150 (42%), Gaps = 6/150 (4%) Query: 49 AGIATHTLIASAFDSREAYDRELIHEIDMYAPD--VVVLAGFMRILSPAFVSHYAGRLLN 106 G + L F ++ +I D Y + + + F +I+ P+ +H R+ N Sbjct: 57 HGNDSFQLSFKKFCI--QFNIPIISLEDAYHLEDAIFLSLEFDKIIHPSKFTH--NRIFN 112 Query: 107 IHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDIT 166 IH S LP Y G++T + N ++E G ++H + +D G +I Q K P+ ++ + Sbjct: 113 IHFSYLPAYKGMYTSAWPILNNEQESGVTLHKIDHGIDTGAIIDQQKFPLDIEETAKTLY 172 Query: 167 ARVQTQEHAIYPLVISWFADGRLKMHENAA 196 + I + G + E +A Sbjct: 173 LKYIKIGTEIVIKNLPALISGNYSIVEQSA 202 >5UIL-A nrPDB Length = 405 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 60/133 (45%), Gaps = 6/133 (4%) Query: 39 DAFGLERARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPD--VVVLAGFMRILSPAF 96 + + + A GI T + +I + Y D + + F +I+ P+ Sbjct: 34 EIYAICNANDTGIDTFQRSFKKYCK--DNLIPIISLAEAYKIDDAIFLSLEFDKIVQPSK 91 Query: 97 VSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPV 156 +H L NIH S LPKY G++T + NG++ G ++H + +D G +I Q ++ + Sbjct: 92 FNH--NELFNIHFSYLPKYKGMYTSAWPILNGEDTSGVTLHKIDHGIDTGAIIAQKEIII 149 Query: 157 FAGDSEDDITARV 169 ++ D+ + Sbjct: 150 QPFETAKDLYEKY 162 >5VYQ-A nrPDB Length = 255 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 62/164 (37%), Gaps = 8/164 (4%) Query: 28 GTVRAVFSNKADAFGLE---RARQAGIATHTLIASAFDSREAYD-RELIHEIDMYAPDVV 83 + ++ A L +AR + + D E + EI D+V Sbjct: 21 MVTILILTDNVHAHALAVDLQARHGDMDVYQSPIGQLPGVPRCDVAERVAEIVERY-DLV 79 Query: 84 VLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDEL 143 + + A + R +N+HP P G ++ +G + G ++H + D+L Sbjct: 80 LSFHCKQRFPAALIDGV--RCVNVHPGFNPYNRGWFPQVFSIIDGQKV-GVTIHEIDDQL 136 Query: 144 DGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADG 187 D GP+I Q + + + DS + AR+ E + DG Sbjct: 137 DHGPIIAQRECAIESWDSSGSVYARLMDIERELVLEHFDAIRDG 180 >4NV1-C nrPDB Length = 243 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 3/109 (2%) Query: 81 DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVT 140 D+ ++ V+ +NIHP L P G ++ N G ++H + Sbjct: 69 DLGFSCHSKQLFPAKLVNSVL--CINIHPGLNPYNRGWFPQVFSIIN-KLPIGATIHVMD 125 Query: 141 DELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRL 189 +E+D G +I+Q +V V + ++ D+ A+VQ +E ++ VI + + Sbjct: 126 EEIDHGDIIIQEEVEVNSFENSFDVYAKVQKKEVELFTKVIDDILNNKF 174 >6CI4-A nrPDB Length = 217 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 50/128 (39%), Gaps = 10/128 (7%) Query: 80 PDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFV 139 D ++ G+ I+ P V + R +N+H S LP G + + D G ++H++ Sbjct: 66 VDFIISYGYRYIIHPDIVERFKQRAINLHISYLPWNKGADPNLWSFLE-DSPKGVTIHYI 124 Query: 140 TDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLD 199 LD G +I+Q +V + D+ R+ ++ G++ Sbjct: 125 DSGLDTGEIIVQREVTYYENDTLRTTYERLTQTIEKLFMEYWPLIRLGKI---------R 175 Query: 200 GQRLPPQG 207 G P G Sbjct: 176 GIPQPKGG 183 >6CI2-A nrPDB Length = 192 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 50/128 (39%), Gaps = 10/128 (7%) Query: 80 PDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFV 139 D ++ G+ I+ P V + R +N+H S LP G + + D G ++H++ Sbjct: 41 VDFIISYGYRYIIHPDIVERFKQRAINLHISYLPWNKGADPNLWSFLE-DSPKGVTIHYI 99 Query: 140 TDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLD 199 LD G +I+Q +V + D+ R+ ++ G++ Sbjct: 100 DSGLDTGEIIVQREVTYYENDTLRTTYERLTQTIEKLFMEYWPLIRLGKI---------R 150 Query: 200 GQRLPPQG 207 G P G Sbjct: 151 GIPQPKGG 158 >6NBP-A nrPDB Length = 263 Score = 97.8 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 46/114 (40%), Gaps = 5/114 (4%) Query: 68 DRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALEN 127 + + I+ Y D+V +I + +N HP L P G + ++ N Sbjct: 78 EFTVERIINEY--DLVFSLHCKQIFPAKLTDNVC--CINFHPGLNPYNRGWYPQAFSIIN 133 Query: 128 GDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVI 181 G G ++H + E+D G +I Q +V V D+ + +V E + I Sbjct: 134 G-LPTGATIHLMDAEVDHGDIIDQQEVEVKMSDTSLTVYRKVIAIEKHLISRNI 186 >4YFV-A nrPDB Length = 254 Score = 96.6 bits (239), Expect = 7e-21, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 48/110 (43%), Gaps = 3/110 (2%) Query: 82 VVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTD 141 +++ A +I V++ +NIHP L P G ++ N + G ++H + Sbjct: 70 LIISAHCKQIFPAHIVNN--KLCINIHPGLNPYNRGWFPQVFSILN-KKPIGATIHKMDS 126 Query: 142 ELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKM 191 E+D G + Q +V + + ++ DI +V E + + + L+ Sbjct: 127 EVDHGEIYCQEEVSILSHETSIDIYNKVIELEKKLIKNNLLKIINNELQP 176 >4LY0-A nrPDB Length = 274 Score = 95.9 bits (237), Expect = 1e-20, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 68/188 (36%), Gaps = 11/188 (5%) Query: 3 IVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFD 62 I + I+G + + N + V NK D GI + F Sbjct: 4 IKICIAGKNNIAVNSLQFILKNYFEADQIVVIPNKNDK---------GIDSWQKSLLKFA 54 Query: 63 SREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHR 122 + EI + F +I+ + + RL NIH S LPKY G+ T Sbjct: 55 LDNNIKIVTLDEIYNIEQIIFFSLEFDQII--KIENFKSDRLFNIHFSALPKYKGVFTSI 112 Query: 123 QALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVIS 182 + N + E G ++H + + +D G +I Q P+ D+ D+ +I+ I Sbjct: 113 TPILNNELESGVTLHRIDNGIDTGNIIDQHCFPIDINDTARDLYFNYLKYGESIFKKNIQ 172 Query: 183 WFADGRLK 190 + K Sbjct: 173 TIINNSYK 180 >6CUL-A nrPDB Length = 275 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 50/142 (35%), Gaps = 30/142 (21%) Query: 64 REAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSH---YAGRLLNIHPSL--------- 111 + ++R L + DVVVL G + IL V +A R++NIHP + Sbjct: 124 KSDFERRLHDTLVELGADVVVLDGLLVIL-DELVRPGAPFARRIMNIHPGVTREDSPYER 182 Query: 112 ---------LPKYPGLHTHRQALENGDEE-----HGTSVHFVTDELDGGPVI-LQAKVPV 156 L G A G S H+V + +D G V K + Sbjct: 183 RGAYATLDALYGARGEKVVDWATMEKVAVEPLYWTGASFHYVDNGIDSGEVFHDVLKTEI 242 Query: 157 FAGDSEDDITARVQTQEHAIYP 178 D+ + R ++++P Sbjct: 243 SPDDTI--LELRWNNFNNSLFP 262 >1ZGH-A nrPDB Length = 260 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 40/105 (38%), Gaps = 4/105 (3%) Query: 68 DRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALEN 127 D ++ + P+ ++ + I+ ++ + H + LP G + +E Sbjct: 66 DELTFEKVKLINPEYILFPHWSWIIPKEIFENFT--CVVFHMTDLPFGRGGSPLQNLIER 123 Query: 128 GDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQ 172 G ++ S V +D G + + + ++ + ++I R Sbjct: 124 GIKKTKISAIKVDGGIDTGDIFFKRDLDLYG--TAEEIFMRASKI 166 >3FXA-A nrPDB Length = 201 Score = 30.8 bits (68), Expect = 0.46, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 39/106 (36%), Gaps = 9/106 (8%) Query: 3 IVVLISGNGSN--LQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHT-LIAS 59 I++LIS G+ L +I ACKT T+ V + D+ A++A I + Sbjct: 95 ILILISKGGNTGELLNLIPACKTK--GSTLIGV-TENPDSV---IAKEADIFFPVSVSKE 148 Query: 60 AFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLL 105 + I + +V L +M F + G + Sbjct: 149 PDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAV 194 >4ZMS-A nrPDB Length = 207 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 31/68 (45%), Gaps = 1/68 (1%) Query: 16 AIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEI 75 +++ ++ K++ V V + K + ERA +AG+ + L + ++ Sbjct: 71 EVLEWIRSEKLETKVVVVTTFKRAGY-FERAVKAGVDAYVLKERSIADLMQTLHTVLEGR 129 Query: 76 DMYAPDVV 83 Y+P+++ Sbjct: 130 KEYSPELM 137 >1VKY-A nrPDB Length = 347 Score = 29.6 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%), Gaps = 4/46 (8%) Query: 148 VILQAKVPVFAGDSED--DITARVQTQEHAIYPLVISWFADGRLKM 191 +I Q PV D+ + + Q EH I+ +I + G L + Sbjct: 26 LIAQE--PVEPRDASRLMVLHRKTQRIEHRIFREIIEYLEPGDLLV 69 >4E7O-A nrPDB Length = 150 Score = 29.2 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 31/68 (45%), Gaps = 1/68 (1%) Query: 16 AIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEI 75 +++ ++ K++ V V + K + ERA +AG+ + L + ++ Sbjct: 83 EVLEWIRSEKLETKVVVVTTFKRAGY-FERAVKAGVDAYVLKERSIADLMQTLHTVLEGR 141 Query: 76 DMYAPDVV 83 Y+P+++ Sbjct: 142 KEYSPELM 149 >3CXM-A nrPDB Length = 268 Score = 29.2 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 24/60 (40%), Gaps = 5/60 (8%) Query: 65 EAYDRELIHEIDMYAPD-VVVL--AGFMRILSPAFVSHYAGRLL-NIHPSLLPKYPGLHT 120 A+ +I + + P+ +V L G+ + + +L N+HPS L G Sbjct: 180 AAFTDAVIQHLSQHHPNRLVFLLWGGYAQ-QKKRLIDANRHVVLENVHPSPLSANRGWFG 238 >1D7K-A nrPDB Length = 421 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 6/31 (19%), Positives = 12/31 (38%) Query: 136 VHFVTDELDGGPVILQAKVPVFAGDSEDDIT 166 HF+ + ++ Q V + D +D Sbjct: 5 CHFLDEGFTAKDILDQKINEVSSSDDKDAFY 35 >1RT8-A nrPDB Length = 513 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 25/79 (31%), Gaps = 13/79 (16%) Query: 94 PAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALEN-GDEEHGT------------SVHFVT 140 P + L N HP L P + + G+ E S+H Sbjct: 248 PKLNLAFVAHLFNTHPGLEPLNEEEKPEIEPFDAEGEREARVFTLWLNSLDVTPSIHDFF 307 Query: 141 DELDGGPVILQAKVPVFAG 159 + L G ++LQA + Sbjct: 308 NNLRDGLILLQAYDKITPN 326 >7ODC-A nrPDB Length = 424 Score = 27.7 bits (60), Expect = 3.9, Method: Composition-based stats. Identities = 5/31 (16%), Positives = 11/31 (35%) Query: 136 VHFVTDELDGGPVILQAKVPVFAGDSEDDIT 166 H + + ++ Q V + D +D Sbjct: 11 CHILDEGFTAKDILDQKINEVSSSDDKDAFY 41 >1M32-A nrPDB Length = 366 Score = 26.9 bits (58), Expect = 6.3, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 122 RQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYP 178 +++L G G + + DEL P+I P + R++ Q IYP Sbjct: 275 QRSLVAGMRALGFNT-LLDDEL-HSPIITAFYSPEDPQYRFSEFYRRLKEQGFVIYP 329 >2YXZ-A nrPDB Length = 311 Score = 26.9 bits (58), Expect = 7.1, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 15/31 (48%), Gaps = 1/31 (3%) Query: 179 LVISWFADGRLKMHENAAWLDGQRLPPQGYA 209 + F GR+ E +L G LP +GYA Sbjct: 280 KGLPLFRAGRVVAGE-GVYLRGAPLPRKGYA 309 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.138 0.358 Lambda K H 0.267 0.0424 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,020,207 Number of Sequences: 36641 Number of extensions: 310219 Number of successful extensions: 933 Number of sequences better than 10.0: 54 Number of HSP's better than 10.0 without gapping: 87 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 810 Number of HSP's gapped (non-prelim): 98 length of query: 212 length of database: 10,336,785 effective HSP length: 93 effective length of query: 119 effective length of database: 6,929,172 effective search space: 824571468 effective search space used: 824571468 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.5 bits)