BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P08165 (492 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1E1N-A nrPDB 930 0.0 1LQU-A nrPDB 300 1e-81 4YRY-B nrPDB 76 4e-14 5JFC-L nrPDB 65 5e-11 5VJ7-A nrPDB 58 1e-08 2VDC-G nrPDB 42 5e-04 1NHQ-A nrPDB 40 0.003 2GV8-A nrPDB 31 1.4 1VDC-A nrPDB 29 3.9 1IUG-A nrPDB 29 4.8 4EMJ-A nrPDB 28 6.4 >1E1N-A nrPDB Length = 460 Score = 930 bits (2403), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/460 (100%), Positives = 460/460 (100%) Query: 33 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKN 92 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKN Sbjct: 1 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKN 60 Query: 93 VINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGV 152 VINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGV Sbjct: 61 VINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGV 120 Query: 153 FSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAA 212 FSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAA Sbjct: 121 FSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAA 180 Query: 213 LGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAAR 272 LGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAAR Sbjct: 181 LGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAAR 240 Query: 273 PRKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVT 332 PRKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVT Sbjct: 241 PRKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVT 300 Query: 333 RLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVP 392 RLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVP Sbjct: 301 RLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVP 360 Query: 393 GLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPGSAFIKALLDSRGVW 452 GLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPGSAFIKALLDSRGVW Sbjct: 361 GLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPGSAFIKALLDSRGVW 420 Query: 453 PVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH 492 PVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH Sbjct: 421 PVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH 460 >1LQU-A nrPDB Length = 456 Score = 300 bits (767), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 186/462 (40%), Positives = 262/462 (56%), Gaps = 27/462 (5%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAH-----VDIYEKQLVPFGLVRFGVAPDHPEVKNVIN 95 I +VGSGP+ F+ A LLK VD+ E P+GLVR GVAPDHP++K++ Sbjct: 6 IAIVGSGPSAFFAAASLLKAADTTEDLDMAVDMLEMLPTPWGLVRSGVAPDHPKIKSISK 65 Query: 96 TFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSA 155 F +TA R F+GNV VG V EL + Y AV+ + GA+ + L+IPGE+LPG +A Sbjct: 66 QFEKTAEDPRFRFFGNVVVGEHVQPGELSERYDAVIYAVGAQSDRMLNIPGEDLPGSIAA 125 Query: 156 RAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAALGA 215 FVGWYN P +++PDLS AV++G GNVALDVARILLT PD L +TDI + AL + Sbjct: 126 VDFVGWYNAHPHFEQVSPDLSGARAVVIGNGNVALDVARILLTDPDVLARTDIADHALES 185 Query: 216 LRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEA-ARPR 274 LR ++ V IVGRRGPLQ AFT ELRE+ L G ++DPA+ G+ D A + Sbjct: 186 LRPRGIQEVVIVGRRGPLQAAFTTLELRELADLDGVDVVIDPAELDGITDEDAAAVGKVC 245 Query: 275 KRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVTRL 334 K+ +++L A +P R RF SP ++ G+R R+ + R Sbjct: 246 KQNIKVLRGYADREP--------RPGHRRMVFRFLTSPIEI----KGKRKVE-RIVLGRN 292 Query: 335 EGIGEAT---RAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDV 391 E + + + A TG+ E+LP LV+ S+GY+ P P +PFD + G +PN+ GR+ Sbjct: 293 ELVSDGSGRVAAKDTGEREELPAQLVVRSVGYRGVPT-PGLPFDDQSGTIPNVGGRINGS 351 Query: 392 PGLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDL----KAGHLPSGPRPGSAFIKALLD 447 P Y GW+KRGPTGVI T D+ T L+++L + S P + + L Sbjct: 352 PNEYVVGWIKRGPTGVIGTNKKDAQDTVDTLIKNLGNAKEGAECKSFPEDHADQVADWLA 411 Query: 448 SRGVWPVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRL 489 +R V+ + W+ +DA E + G+ G+PR KL E+LR+ Sbjct: 412 ARQPKLVTSAHWQVIDAFERAAGEPHGRPRVKLASLAELLRI 453 >4YRY-B nrPDB Length = 468 Score = 75.9 bits (185), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 56/166 (33%), Positives = 80/166 (48%), Gaps = 10/166 (6%) Query: 37 QTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINT 96 + ++ VVGSGPAG A L K HVDI+E P G++ +G+ P+ K ++ Sbjct: 139 KKEKVAVVGSGPAGLTAAADLAKMGY--HVDIFEAFHKPGGVLVYGI-PEFRLPKRIVER 195 Query: 97 FTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSAR 156 R F+ N VG+ V V+EL Y AV + GA + + IPG L GV+SA Sbjct: 196 EVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSAN 255 Query: 157 AFVGWYNGLPENRELAPDLSCDTAV-----ILGQGNVALDVARILL 197 F+ N + L P+ V ++G GN A+D AR L Sbjct: 256 EFLTRVNLM--KAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSAL 299 >5JFC-L nrPDB Length = 474 Score = 65.5 bits (158), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 46/161 (28%), Positives = 75/161 (46%), Gaps = 6/161 (3%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQ 99 ++ ++G+GPAG A L K V IYE P G++ +G+ P+ K ++ + Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGY--EVTIYEALHQPGGVLIYGI-PEFRLPKEIVKKELE 212 Query: 100 TARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFV 159 R NV VG+ +T +EL++ Y A+ + GA + PG L G++SA F+ Sbjct: 213 NLRRLGVKIETNVLVGKTITFEELREEYDAIFIGTGAGTPRIYPWPGVNLNGIYSANEFL 272 Query: 160 GWYNGLPENRELAPDLSCDTA---VILGQGNVALDVARILL 197 N + + D ++G GN A+D AR L Sbjct: 273 TRINLMKAYKFPEYDTPIKVGKRVAVIGGGNTAMDAARSAL 313 >5VJ7-A nrPDB Length = 476 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 103/233 (44%), Gaps = 34/233 (14%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQ 99 ++ ++G+GPAG A L K V IYE P G++ +G+ P+ K ++ + Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGY--EVTIYEALHQPGGVLTYGI-PEFRLPKEILRKELK 212 Query: 100 TARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFV 159 + VG+ +T+QEL Y AV + GA + +IPG L G++SA F+ Sbjct: 213 KLSLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPKLPNIPGINLNGIYSANEFL 272 Query: 160 GWYN-----GLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAALG 214 N PE P + V++G GN A+D AR L LG Sbjct: 273 TRINLMKAYKFPEYD--TPIVVGKKVVVIGAGNTAMDAARSALR--------------LG 316 Query: 215 ALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPM--LDPADFLGLQD 265 A V I RRG + I+E++ + G + M ++P +F+G ++ Sbjct: 317 A-------EVTIAYRRGREDMTARIEEVKHA-EEEGVKFMFFVNPVEFIGDEN 361 >2VDC-G nrPDB Length = 456 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 35/138 (25%), Positives = 66/138 (47%), Gaps = 7/138 (5%) Query: 66 VDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQD 125 V +Y++ GL+ +G+ P K+V+ + ++ N EVGRD ++ EL+ Sbjct: 148 VHVYDRYDRMGGLLVYGI-PGFKLEKSVVERRVKLLADAGVIYHPNFEVGRDASLPELRR 206 Query: 126 AYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYN--GLPENRELAPDLSCDTA--- 180 + AV+++ G + + PG L + +A ++ N L + E + S + A Sbjct: 207 KHVAVLVATGVYKARDIKAPGSGLGNIVAALDYLTTSNKVSLGDTVEAYENGSLNAAGKH 266 Query: 181 -VILGQGNVALDVARILL 197 V+LG G+ A+D R + Sbjct: 267 VVVLGGGDTAMDCVRTAI 284 >1NHQ-A nrPDB Length = 447 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 45/190 (23%), Positives = 80/190 (42%), Gaps = 20/190 (10%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEK-QLVPF---GLVRF--GVAPDHPEVKNV 93 ++ V+GS G+ + LL H A + YEK + F G+ + G D V+ + Sbjct: 2 KVIVLGSSHGGYEAVEELLNLHPDAEIQWYEKGDFISFLSSGMQLYLEGKVKDVNSVRYM 61 Query: 94 ---------INTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDI 144 +N F+ T + V V V+ +E + Y +++S GA + LDI Sbjct: 62 TGEKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVENYDKLIISPGAVPFE-LDI 120 Query: 145 PGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLE 204 PG++L ++ R W L ++ D + V++G G + ++ A + Sbjct: 121 PGKDLDNIYLMRGR-QWAIKL---KQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKVT 176 Query: 205 KTDITEAALG 214 DI + LG Sbjct: 177 VIDILDRPLG 186 >2GV8-A nrPDB Length = 447 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 13/42 (30%), Positives = 26/42 (61%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRF 81 +I ++G+GP+G TA+ LL + V ++E++ P G+ + Sbjct: 8 KIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGGVWNY 49 >1VDC-A nrPDB Length = 333 Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 338 GEATRAVPTGDVEDLPCGLVLSSIGYK--SRPIDPSVPFDPKLGVVPNMEGRVVDVPGLY 395 G + V TGDV DL + +IG++ ++ +D V D VV VPG++ Sbjct: 232 GLKVKNVVTGDVSDLKVSGLFFAIGHEPATKFLDGGVELDSDGYVVTKPGTTQTSVPGVF 291 Query: 396 CSGWVK 401 +G V+ Sbjct: 292 AAGDVQ 297 >1IUG-A nrPDB Length = 352 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 386 GRVVDVPGLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPG 438 G + D+P L + ++ P G++ M S L G++ L+ + SG + G Sbjct: 135 GALADLPAL-ARAFKEKNPEGLVGADMVTSLLVGEVALEAMGVDAAASGSQKG 186 >4EMJ-A nrPDB Length = 410 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 32/140 (22%), Positives = 62/140 (44%), Gaps = 34/140 (24%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVD-IYEKQLVPFGLVRFGVAPDHPEV-KNVINTF 97 + ++G+G GF TAQ L + I ++ +P+ D P + K V++ Sbjct: 4 HVAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPY---------DRPSLSKAVLDGS 54 Query: 98 TQ----TARSDRCAFYGNVEV----GRDVTVQELQD-----------AYHAVVLSYGAED 138 + A +D +YG + G +VT ++Q + A+V++ G+ Sbjct: 55 LERPPILAEAD---WYGEARIDMLTGPEVTALDVQTRTISLDDGTTLSADAIVIATGSR- 110 Query: 139 HQALDIPGEELPGVFSARAF 158 + + +PG +LPGV + R + Sbjct: 111 ARTMALPGSQLPGVVTLRTY 130 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1E1N-A nrPDB 722 0.0 1LQU-A nrPDB 625 e-179 5VJ7-A nrPDB 255 3e-68 5JFC-L nrPDB 248 5e-66 4YRY-B nrPDB 245 3e-65 2VDC-G nrPDB 177 1e-44 Sequences not found previously or not previously below threshold: 1PS9-A nrPDB 57 2e-08 1NHQ-A nrPDB 56 3e-08 5MJK-A nrPDB 49 4e-06 2ZBW-A nrPDB 49 4e-06 2Q7V-A nrPDB 48 8e-06 5UTH-A nrPDB 47 2e-05 5NMX-A nrPDB 46 5e-05 3AB1-A nrPDB 45 5e-05 2GV8-A nrPDB 44 1e-04 4ZN0-A nrPDB 44 1e-04 5YGQ-A nrPDB 44 1e-04 5ER0-A nrPDB 43 3e-04 3FG2-P nrPDB 43 3e-04 5W4C-A nrPDB 43 3e-04 6GAS-A nrPDB 43 4e-04 3LZX-A nrPDB 43 4e-04 2CDU-A nrPDB 42 6e-04 4IV9-A nrPDB 41 0.001 4CBQ-A nrPDB 40 0.002 3D8X-A nrPDB 40 0.003 2JB2-A nrPDB 39 0.005 3F8P-A nrPDB 39 0.005 4GCM-A nrPDB 39 0.006 1XHC-A nrPDB 38 0.008 6BWT-A nrPDB 38 0.010 4EMJ-A nrPDB 37 0.013 3RHA-A nrPDB 37 0.014 4JDR-A nrPDB 37 0.020 5XHU-A nrPDB 37 0.021 1F8S-A nrPDB 36 0.029 2A87-A nrPDB 36 0.030 6GAR-A nrPDB 36 0.040 3OC4-A nrPDB 35 0.049 3C4A-A nrPDB 35 0.050 6DU7-A nrPDB 35 0.051 5ZBC-A nrPDB 35 0.054 4Y4M-A nrPDB 35 0.060 1VDC-A nrPDB 35 0.064 3ISH-A nrPDB 35 0.075 5TWC-A nrPDB 35 0.085 2VOU-A nrPDB 35 0.085 4Y4N-A nrPDB 35 0.090 5UWY-A nrPDB 35 0.093 2TMD-A nrPDB 34 0.12 3WE0-A nrPDB 34 0.15 5U63-A nrPDB 34 0.17 3LXD-A nrPDB 34 0.18 1SEZ-A nrPDB 34 0.22 3FPZ-A nrPDB 33 0.24 4FX9-A nrPDB 33 0.27 2CVJ-A nrPDB 33 0.33 1RP0-A nrPDB 33 0.35 6GB2-BC nrPDB 32 0.46 4JNQ-A nrPDB 32 0.64 4Q20-A nrPDB 32 0.65 3UKH-A nrPDB 32 0.71 3NIX-A nrPDB 32 0.73 1Q1R-A nrPDB 32 0.77 2R9Z-A nrPDB 32 0.89 4ZCC-A nrPDB 31 1.2 3K30-A nrPDB 31 1.4 3KKJ-A nrPDB 30 1.6 3HN2-A nrPDB 30 1.8 2GMH-A nrPDB 30 1.9 4YWO-A nrPDB 30 2.0 3L1R-A nrPDB 30 2.0 5MOG-A nrPDB 30 2.1 6DLL-A nrPDB 30 2.6 1DOD-A nrPDB 30 2.9 1FCD-A nrPDB 29 4.3 5YFP-H nrPDB 29 4.6 4NTC-A nrPDB 29 4.6 2REM-A nrPDB 29 4.7 2YQU-A nrPDB 29 5.3 1WDI-A nrPDB 28 8.9 >1E1N-A nrPDB Length = 460 Score = 722 bits (1863), Expect = 0.0, Method: Composition-based stats. Identities = 460/460 (100%), Positives = 460/460 (100%) Query: 33 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKN 92 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKN Sbjct: 1 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKN 60 Query: 93 VINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGV 152 VINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGV Sbjct: 61 VINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGV 120 Query: 153 FSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAA 212 FSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAA Sbjct: 121 FSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAA 180 Query: 213 LGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAAR 272 LGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAAR Sbjct: 181 LGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAAR 240 Query: 273 PRKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVT 332 PRKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVT Sbjct: 241 PRKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVT 300 Query: 333 RLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVP 392 RLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVP Sbjct: 301 RLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVP 360 Query: 393 GLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPGSAFIKALLDSRGVW 452 GLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPGSAFIKALLDSRGVW Sbjct: 361 GLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPRPGSAFIKALLDSRGVW 420 Query: 453 PVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH 492 PVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH Sbjct: 421 PVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH 460 >1LQU-A nrPDB Length = 456 Score = 625 bits (1613), Expect = e-179, Method: Composition-based stats. Identities = 186/462 (40%), Positives = 262/462 (56%), Gaps = 27/462 (5%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAH-----VDIYEKQLVPFGLVRFGVAPDHPEVKNVIN 95 I +VGSGP+ F+ A LLK VD+ E P+GLVR GVAPDHP++K++ Sbjct: 6 IAIVGSGPSAFFAAASLLKAADTTEDLDMAVDMLEMLPTPWGLVRSGVAPDHPKIKSISK 65 Query: 96 TFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSA 155 F +TA R F+GNV VG V EL + Y AV+ + GA+ + L+IPGE+LPG +A Sbjct: 66 QFEKTAEDPRFRFFGNVVVGEHVQPGELSERYDAVIYAVGAQSDRMLNIPGEDLPGSIAA 125 Query: 156 RAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAALGA 215 FVGWYN P +++PDLS AV++G GNVALDVARILLT PD L +TDI + AL + Sbjct: 126 VDFVGWYNAHPHFEQVSPDLSGARAVVIGNGNVALDVARILLTDPDVLARTDIADHALES 185 Query: 216 LRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEA-ARPR 274 LR ++ V IVGRRGPLQ AFT ELRE+ L G ++DPA+ G+ D A + Sbjct: 186 LRPRGIQEVVIVGRRGPLQAAFTTLELRELADLDGVDVVIDPAELDGITDEDAAAVGKVC 245 Query: 275 KRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVTRL 334 K+ +++L A +P R RF SP ++ G+R R+ + R Sbjct: 246 KQNIKVLRGYADREP--------RPGHRRMVFRFLTSPIEI----KGKRKVE-RIVLGRN 292 Query: 335 EGIGEAT---RAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDV 391 E + + + A TG+ E+LP LV+ S+GY+ P P +PFD + G +PN+ GR+ Sbjct: 293 ELVSDGSGRVAAKDTGEREELPAQLVVRSVGYRGVPT-PGLPFDDQSGTIPNVGGRINGS 351 Query: 392 PGLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDL----KAGHLPSGPRPGSAFIKALLD 447 P Y GW+KRGPTGVI T D+ T L+++L + S P + + L Sbjct: 352 PNEYVVGWIKRGPTGVIGTNKKDAQDTVDTLIKNLGNAKEGAECKSFPEDHADQVADWLA 411 Query: 448 SRGVWPVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRL 489 +R V+ + W+ +DA E + G+ G+PR KL E+LR+ Sbjct: 412 ARQPKLVTSAHWQVIDAFERAAGEPHGRPRVKLASLAELLRI 453 >5VJ7-A nrPDB Length = 476 Score = 255 bits (652), Expect = 3e-68, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 106/241 (43%), Gaps = 30/241 (12%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQ 99 ++ ++G+GPAG A L K V IYE P G++ +G+ P+ K ++ + Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGY--EVTIYEALHQPGGVLTYGI-PEFRLPKEILRKELK 212 Query: 100 TARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFV 159 + VG+ +T+QEL Y AV + GA + +IPG L G++SA F+ Sbjct: 213 KLSLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPKLPNIPGINLNGIYSANEFL 272 Query: 160 GWYNGLPENRELAPDLS---CDTAVILGQGNVALDVARILLTPPDHLEKTDITEAALGAL 216 N + + D V++G GN A+D AR L LGA Sbjct: 273 TRINLMKAYKFPEYDTPIVVGKKVVVIGAGNTAMDAARSALR--------------LGA- 317 Query: 217 RQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPM--LDPADFLGLQDRIKEAARPR 274 V I RRG + I+E++ + G + M ++P +F+G ++ +A + Sbjct: 318 ------EVTIAYRRGREDMTARIEEVKHA-EEEGVKFMFFVNPVEFIGDENGNVKAVKFE 370 Query: 275 K 275 K Sbjct: 371 K 371 >5JFC-L nrPDB Length = 474 Score = 248 bits (632), Expect = 5e-66, Method: Composition-based stats. Identities = 66/286 (23%), Positives = 115/286 (40%), Gaps = 38/286 (13%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQ 99 ++ ++G+GPAG A L K V IYE P G++ +G+ P+ K ++ + Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGY--EVTIYEALHQPGGVLIYGI-PEFRLPKEIVKKELE 212 Query: 100 TARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFV 159 R NV VG+ +T +EL++ Y A+ + GA + PG L G++SA F+ Sbjct: 213 NLRRLGVKIETNVLVGKTITFEELREEYDAIFIGTGAGTPRIYPWPGVNLNGIYSANEFL 272 Query: 160 GWYNGLPENRELAPDLS---CDTAVILGQGNVALDVARILLTPPDHLEKTDITEAALGAL 216 N + + D ++G GN A+D AR L LGA Sbjct: 273 TRINLMKAYKFPEYDTPIKVGKRVAVIGGGNTAMDAARSALR--------------LGA- 317 Query: 217 RQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPM--LDPADFLGLQDRIKEAARPR 274 VWI+ RR ++ +E + + G + M + P F+G ++ +A Sbjct: 318 ------EVWILYRRTRKEMTAREEE-IKHAEEEGVKFMFLVTPKRFIGDENGNLKAIELE 370 Query: 275 KRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPD 320 K + +P R + + F + + +P+ Sbjct: 371 KMKLG--------EPDESGRRRPIPTGETFIMEFDTAIIAIGQTPN 408 >4YRY-B nrPDB Length = 468 Score = 245 bits (625), Expect = 3e-65, Method: Composition-based stats. Identities = 70/264 (26%), Positives = 110/264 (41%), Gaps = 29/264 (10%) Query: 37 QTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINT 96 + ++ VVGSGPAG A L K HVDI+E P G++ +G+ P+ K ++ Sbjct: 139 KKEKVAVVGSGPAGLTAAADLAKMGY--HVDIFEAFHKPGGVLVYGI-PEFRLPKRIVER 195 Query: 97 FTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSAR 156 R F+ N VG+ V V+EL Y AV + GA + + IPG L GV+SA Sbjct: 196 EVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLNGVYSAN 255 Query: 157 AFVGWYNGLPENRELAPDLS---CDTAVILGQGNVALDVARILLTPPDHLEKTDITEAAL 213 F+ N + D ++G GN A+D AR L L Sbjct: 256 EFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSALR--------------L 301 Query: 214 GALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRP--MLDPADFLGLQDRIKEAA 271 GA + V+IV RR ++ +E ++ G + P ++G + EA Sbjct: 302 GA------EKVYIVYRRTEREMPARREEYHHALE-EGIEFLWLTLPIRYIGDANGNVEAM 354 Query: 272 RPRKRLMELLLRTATEKPGVEEAA 295 + ++ + +P E + Sbjct: 355 ECVRMELKEADGSGRPRPVPIEGS 378 >2VDC-G nrPDB Length = 456 Score = 177 bits (448), Expect = 1e-44, Method: Composition-based stats. Identities = 55/259 (21%), Positives = 101/259 (38%), Gaps = 45/259 (17%) Query: 14 WTRTRLPPSRSIQNFGQHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQL 73 W + R P ++E + V+G+GPAG A+ L V +Y++ Sbjct: 111 WVKPRTP-------------SRELGLSVGVIGAGPAGLAAAEELRAKGY--EVHVYDRYD 155 Query: 74 VPFGLVRFGVAPDHPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLS 133 GL+ +G+ P K+V+ + ++ N EVGRD ++ EL+ + AV+++ Sbjct: 156 RMGGLLVYGI-PGFKLEKSVVERRVKLLADAGVIYHPNFEVGRDASLPELRRKHVAVLVA 214 Query: 134 YGAEDHQALDIPGEELPGVFSARAFVGWYN--GLPENRELAPDLSCDTA----VILGQGN 187 G + + PG L + +A ++ N L + E + S + A V+LG G+ Sbjct: 215 TGVYKARDIKAPGSGLGNIVAALDYLTTSNKVSLGDTVEAYENGSLNAAGKHVVVLGGGD 274 Query: 188 VALDVARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQ 247 A+D R + +V + RR + + +E+ + Sbjct: 275 TAMDCVRTAIR--------------------QGATSVKCLYRRDRKNMPGSQREVAHA-E 313 Query: 248 LPGTRPMLD--PADFLGLQ 264 G + P F G Sbjct: 314 EEGVEFIWQAAPEGFTGDT 332 >1PS9-A nrPDB Length = 671 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 40/199 (20%), Positives = 67/199 (33%), Gaps = 34/199 (17%) Query: 37 QTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA---PDHPEVKNV 93 Q + VVG+GPAG A + V +++ G +F +A P E Sbjct: 372 QKKNLAVVGAGPAGLAFAINAAARGH--QVTLFDAHSEIGG--QFNIAKQIPGKEEFYET 427 Query: 94 INTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVF 153 + + + N VT +L A+ +L+ G + I G + P V Sbjct: 428 LRYYRRMIEVTGVTLKLNH----TVTADQL-QAFDETILASGI-VPRTPPIDGIDHPKVL 481 Query: 154 SARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKT------- 206 S + R+ AP + I+G G + D A L P + + Sbjct: 482 SYLDVL---------RDKAP--VGNKVAIIGCGGIGFDTAMYLSQPGESTSQNIAGFCNE 530 Query: 207 ---DITEAALGALRQSRVK 222 D + G L ++ Sbjct: 531 WGIDSSLQQAGGLSPQGMQ 549 >1NHQ-A nrPDB Length = 447 Score = 56.3 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 51/268 (19%), Positives = 93/268 (34%), Gaps = 28/268 (10%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQL----VPFGLVRFGVAPDHPEVKNVIN 95 ++ V+GS G+ + LL H A + YEK + G+ + + +V +V Sbjct: 2 KVIVLGSSHGGYEAVEELLNLHPDAEIQWYEKGDFISFLSSGMQLY-LEGKVKDVNSVRY 60 Query: 96 TFTQTARSDRCAFYGNVE------------VGRDVTVQELQDAYHAVVLSYGAEDHQALD 143 + S + N E V V+ +E + Y +++S GA LD Sbjct: 61 MTGEKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVENYDKLIISPGA-VPFELD 119 Query: 144 IPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHL 203 IPG++L ++ R G + ++ D + V++G G + ++ A + Sbjct: 120 IPGKDLDNIYLMR---GRQWAIK-LKQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKV 175 Query: 204 EKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPG--TRPMLDPADFL 261 DI + LG V + + E E + G + + D + Sbjct: 176 TVIDILDRPLGVYLDKEFTDV-LTEEMEANNITIATGETVERYEGDGRVQKVVTDKNAYD 234 Query: 262 GLQDRIKEAARPRKRLMELLLRTATEKP 289 + RP L T P Sbjct: 235 ADLVVVAVGVRP---NTAWLKGTLELHP 259 >5MJK-A nrPDB Length = 327 Score = 49.3 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 44/256 (17%), Positives = 88/256 (34%), Gaps = 53/256 (20%) Query: 29 GQHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA---- 84 G H + E+ + ++GSGPAG A + + S + E+ VP G + Sbjct: 17 GSHMT--EKKYDVVIIGSGPAGMTAAMYTAR--SEMKTLLLER-GVPGGQMNNTAEIENY 71 Query: 85 PDHPEV--KNVINTFTQTARSDRCAFYGNVEVG--RDVTVQELQDAYH-----AVVLSYG 135 P + + + + G +++ +++++ G Sbjct: 72 PGYETIMGPELSMKMAEPLEGLGVENAYGFVTGIEDHGDYKKIITEDDEFITKSIIIATG 131 Query: 136 AEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARI 195 A +H+ L+IPGEE G N+E+ +++G G+ A++ A Sbjct: 132 A-NHRKLEIPGEEEYGARGVSYCAVCDGAFFRNQEI---------LVIGGGDSAVEEALY 181 Query: 196 LLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPML 255 L ++V I+ RR L+ I++ + + Sbjct: 182 L---------------------TRFGQSVTIMHRRDKLRAQEIIQQ--RAFKEEKINFIW 218 Query: 256 D--PADFLGLQDRIKE 269 D P + G +I+ Sbjct: 219 DSVPMEIKGDDKKIQS 234 >2ZBW-A nrPDB Length = 335 Score = 49.3 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 80/243 (32%), Gaps = 51/243 (20%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLV--------RFGVAPDHP---- 88 + +VG+GP G + ++ + P G + + VA P Sbjct: 8 VLIVGAGPTGLFAGFYVGMRGLSFR--FVDPLPEPGGQLTALYPEKYIYDVA-GFPKVYA 64 Query: 89 --EVKNVINT------------FTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVL-- 132 VK ++ +T + F G T + AV++ Sbjct: 65 KDLVKGLVEQVAPFNPVYSLGERAETLEREGDLFKVTTSQGNAYTAK-------AVIIAA 117 Query: 133 SYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDV 192 GA + + + PGE R F G G+ + + +I+G G+ A+D Sbjct: 118 GVGAFEPRRIGAPGE--------REFEGR--GVYYAVKSKAEFQGKRVLIVGGGDSAVDW 167 Query: 193 ARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTR 252 A LL + T I ++ VK + G L+V T ELR + R Sbjct: 168 ALNLLDTARRI--TLIHRRPQFRAHEASVKELMKAHEEGRLEV-LTPYELRRVEGDERVR 224 Query: 253 PML 255 + Sbjct: 225 WAV 227 >2Q7V-A nrPDB Length = 325 Score = 48.2 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 37/169 (21%), Positives = 58/169 (34%), Gaps = 31/169 (18%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA----PDHPEV---KNV 93 + ++G GPAG A + + I EK +P G + + P PE + Sbjct: 11 VVIIGGGPAGLTAAIYTGRAQLST--LILEK-GMPGGQIAWSEEVENFPGFPEPIAGMEL 67 Query: 94 INTFTQTARSDRCAFYGNVEVGRD---------VTVQELQDAY--HAVVLSYGAEDHQAL 142 Q A + G TV+ Y AV+L+ GA D + L Sbjct: 68 AQRMHQQAEKFGAKVEMDEVQGVQHDATSHPYPFTVRGYNGEYRAKAVILATGA-DPRKL 126 Query: 143 DIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALD 191 IPGE+ F G + V++G G+ A++ Sbjct: 127 GIPGED--------NFWGKGVSTCATCDGFF-YKGKKVVVIGGGDAAVE 166 >5UTH-A nrPDB Length = 319 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 50/259 (19%), Positives = 84/259 (32%), Gaps = 46/259 (17%) Query: 33 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA---PDHP- 88 ST + + ++GSGPAG+ A + + + V +E L+ P Sbjct: 10 STSQTVHDVIIIGSGPAGYTAAIYAARAQLKPLV--FEGTQFGGALMTTTEVENYPGFRE 67 Query: 89 ------EVKNVINTFTQTARSDR------CAFYGNVEVGRDVTVQELQDAYHAVVLSYGA 136 + + + R G V + V V + AV+L+ GA Sbjct: 68 GITGPELMDQMREQALRFGADLRMEDVDAVQLEGPV---KTVVVGDETHQARAVILAMGA 124 Query: 137 EDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARIL 196 + L +PGEE A +G + D V++G G+ A++ A L Sbjct: 125 -AARHLGVPGEE------ALTGMGVSTCATCDGFFFRDQDI---VVVGGGDSAMEEATFL 174 Query: 197 LTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLD 256 ++ R S+ I+ R T E+ Q+ G D Sbjct: 175 TR----FARSVTLIHRRDEFRASK-----IMLERARANEKITFLTNTEITQIEG-----D 220 Query: 257 PADFLGLQDRIKEAARPRK 275 P G++ R K Sbjct: 221 P-KVTGVRLRDTVTGEESK 238 >5NMX-A nrPDB Length = 425 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 47/242 (19%), Positives = 70/242 (28%), Gaps = 79/242 (32%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFG----------------- 82 ++ V+G+GP+G A++L + V ++E+ G + Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGF--EVMVFERYHHVGGTWNYTDETWMSEDGRPVYSSMY 60 Query: 83 ------------VAPDHPE---------VKNVINTFTQT--ARSDRCAFYGNVEV----- 114 PD P K V+ F A R V Sbjct: 61 QNLFVNLPKELMAFPDFPFHDIEGSYVPSKEVLKYFDNFTDAFDLRKLIKLQHHVENVRP 120 Query: 115 ---GRDVTVQELQD------AYHAVVLSYG-AEDHQALDIPGEELPGVFSARAFVGWYNG 164 G VTV +L + AVV+ G D+ G F G Sbjct: 121 CESGWLVTVTDLTTMVEHSFEFDAVVVCTGQTWCPLYPDVEGRSF--------FRGRLTH 172 Query: 165 LPENRELAPDLSCDTAVILGQGNVALDVA-------------RILLTPPDHLEKTDITEA 211 E R P +I+G G D+A R L P + L ++TE Sbjct: 173 AHEFRSPEP-FRNKRVLIVGAGPSGHDMALHISYVSKEVFLSRKELKPVEGLFPDNVTEK 231 Query: 212 AL 213 L Sbjct: 232 PL 233 >3AB1-A nrPDB Length = 360 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 36/252 (14%), Positives = 79/252 (31%), Gaps = 43/252 (17%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLV--------RFGVAPDHPEVKN 92 + ++G GP G + A + I E G + + VA PEV Sbjct: 17 LTIIGGGPTGIFAAFQCGM--NNISCRIIESMPQLGGQLAALYPEKHIYDVA-GFPEVPA 73 Query: 93 VINTFTQTARSDRCAFYGNVEVGRDVTVQELQD--------------AYHAVVLSYGAED 138 + ++ + + +V + VT D AV+++ G Sbjct: 74 I--DLVESLWAQAERYNPDVVLNETVTKYTKLDDGTFETRTNTGNVYRSRAVLIAAGLGA 131 Query: 139 HQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALD------- 191 + +P +L + + + + + D VI+G G+ ALD Sbjct: 132 FEPRKLP--QLGNI----DHLTGSSVYYAVKSV-EDFKGKRVVIVGGGDSALDWTVGLIK 184 Query: 192 --VARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLP 249 + L+ + T + R + V++ ++ + + + Sbjct: 185 NAASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHLRSSD 244 Query: 250 GTRPMLDPADFL 261 G++ ++ L Sbjct: 245 GSKWTVEADRLL 256 >2GV8-A nrPDB Length = 447 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 27/51 (52%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEV 90 +I ++G+GP+G TA+ LL + V ++E++ P G+ + + Sbjct: 8 KIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGGVWNYTSTLSNKLP 58 >4ZN0-A nrPDB Length = 311 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 39/245 (15%), Positives = 85/245 (34%), Gaps = 49/245 (20%) Query: 43 VVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA---PDHPEVK--NVINTF 97 ++G GPAG + ++ I E+ + + + P P + ++ F Sbjct: 12 IIGGGPAGLTAGIYAVR--YGLDTLILERNEISGQISMADIVENYPGFPSISGLELMERF 69 Query: 98 TQTARSDRCAFYGNVEVG-------RDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELP 150 A+ + + +T AV+++ GA + + L +PGE+ Sbjct: 70 RTHAQEVGVKTTITEVLSVRSEGTKKIITTDSGDLEAKAVIIATGA-NPKHLGVPGEK-E 127 Query: 151 GVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITE 210 + ++ +G P ++G GN +T L K Sbjct: 128 LISKGVSYCAICDG--------PFFRNKIVAVVGGGN-------SAVTDALFLSKV---- 168 Query: 211 AALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDP--ADFLGLQDRIK 268 + V++V RR L+ A +++ + P +L+ + +G ++ IK Sbjct: 169 ----------AQKVYLVHRRDHLKAARVLQD--RVDGTPNIELILNSHVLEIVGTREGIK 216 Query: 269 EAARP 273 + + Sbjct: 217 KVEKI 221 >5YGQ-A nrPDB Length = 342 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 35/186 (18%), Positives = 55/186 (29%), Gaps = 47/186 (25%) Query: 34 TQEQTPQICVVGSGPAGFYTAQHLLKHHSRAH-VDIYEK--------------QLVPFGL 78 T+ + +VG+GP G + L +AH VDI +K +P Sbjct: 2 TETIKTDVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAELYPEKPIYDIPGIP 61 Query: 79 VRFG-------------VAPDHPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQD 125 + G P + V N + N G+ L Sbjct: 62 MVTGHGLTEALMEQIKPFNPTFHLSEMVEN--VEKIGDPGFRVTTN--AGKVFECTVL-- 115 Query: 126 AYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQ 185 V G+ + +PG E A+ G + D +I+G Sbjct: 116 ---VVAAGGGSFLPKRPPVPGVE--------AYEGT--SVHYAVRKMEDFRGKDILIVGG 162 Query: 186 GNVALD 191 G+ ALD Sbjct: 163 GDSALD 168 >5ER0-A nrPDB Length = 518 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 30/170 (17%), Positives = 66/170 (38%), Gaps = 24/170 (14%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPF----GLVRFGVAPDHPEVKNVIN 95 ++ VVG AG + + +L H A V +YE+ V G+ + + + + + Sbjct: 52 KVTVVGCTHAGTFAIKQILAEHPDAEVTVYERNDVISFLSCGIALY-LGGKVADPQGLFY 110 Query: 96 TFTQTARSDRCAFYGNVEV------GRDVTVQEL------QDAYHAVVLSYGAEDHQALD 143 + + + N V + VTV++L ++Y +V++ G+ Sbjct: 111 SSPEELQKLGANVQMNHNVLAIDPDQKTVTVEDLTNHAQTTESYDKLVMTSGSW-PIVPK 169 Query: 144 IPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVA 193 IPG + V + + + + +E ++G G + ++A Sbjct: 170 IPGIDSDRVKLCKNWAHAQALIEDAKEA------KRITVIGAGYIGAELA 213 >3FG2-P nrPDB Length = 404 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 62/167 (37%), Gaps = 20/167 (11%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDI--------YEKQLVPFGLVRFGVAPD---HPE 89 + + G+G AGF A L + + + Y++ + ++ G P+ Sbjct: 4 VLIAGAGHAGFQVAVSLRQAKYPGRIALINDEKHLPYQRPPLSKAYLKSGGDPNSLMFRP 63 Query: 90 VKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEEL 149 K + + + + E + + Y +VL+ GA + + LD+P L Sbjct: 64 EKFFQDQAIELISDRMVSI--DREGRKLLLASGTAIEYGHLVLATGARN-RMLDVPNASL 120 Query: 150 PGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARIL 196 P V ++ + R+ PD V++G G + L+ A Sbjct: 121 PDVL----YLRTLDESEVLRQRMPDK--KHVVVIGAGFIGLEFAATA 161 >5W4C-A nrPDB Length = 371 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 35/222 (15%), Positives = 74/222 (33%), Gaps = 37/222 (16%) Query: 34 TQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQL----VPFGLVRFGVA----P 85 +++ ++ ++GSGP G A +L + +YE L P G + P Sbjct: 26 SKKMHSKVVIIGSGPGGHTAAIYLARA--NLEPVLYEGMLANGFAPGGQLTTTTDVENFP 83 Query: 86 DHPE---VKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQ------------DAYHAV 130 PE +++ F + D++V+ + + Sbjct: 84 GFPEGVTGTEMMDKFRAQSERFGTKIITETVARVDLSVRPFKYWTEGEEEEHEFMTADTI 143 Query: 131 VLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVAL 190 +L+ GA + +PGEE + + P ++G G+ A Sbjct: 144 ILATGASAKRLF-LPGEE-------TYWQSGISACAVCDGAVPIFRQKPLAVIGGGDSAA 195 Query: 191 DVARILLTPPDH----LEKTDITEAALGALRQSRVKTVWIVG 228 + A L H + + ++ + + A R + V ++ Sbjct: 196 EEATYLTKYGSHVYVLVRRDELRASKIMAKRLTSHPKVTVLW 237 >6GAS-A nrPDB Length = 331 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 43/256 (16%), Positives = 75/256 (29%), Gaps = 62/256 (24%) Query: 33 STQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLV--------RFGVA 84 + ++ I ++G GP G +TA +A V I E G + + VA Sbjct: 4 AENQKVYDITIIGGGPTGLFTA--FYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVA 61 Query: 85 PDHPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQ---------------DAYHA 129 P+V+ + F V + V E Q Sbjct: 62 -GFPKVRA--QELVDNLKEQMKKFDPTVCLEEAVDTLEKQADGIFKLVTNKQTHYSKSVI 118 Query: 130 VVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVA 189 + GA + L++ G + FV N + V+ G G+ A Sbjct: 119 ITAGNGAFQPRRLELEGTAKYEKKNLHYFVDDMNKF----------AGKRVVVFGGGDSA 168 Query: 190 LDVARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQV-AFTIKELREMIQL 248 +D +L + + V IV RR + +++ L Sbjct: 169 VDWTMML---------------------EPIAEKVTIVHRRDKFRAHEHSVENLMNSRAE 207 Query: 249 PGTRPMLDPADFLGLQ 264 T + P + +G Sbjct: 208 VSTPYV--PVELIGDD 221 >3LZX-A nrPDB Length = 332 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 84/249 (33%), Gaps = 55/249 (22%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLV--------RFGVA--PDHPEV 90 I ++G GP G +TA +A V I E G + + VA P Sbjct: 10 ITIIGGGPVGLFTA--FYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKIRAQ 67 Query: 91 KNVINTFTQTARSDRCAFYGNVE---------VGRDVTVQELQ-DAYHAVVLSYGAEDHQ 140 + + N Q A+ D+ V + VT +E + GA + Sbjct: 68 ELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVTNEETHYSKTVIITAGNGAFKPR 127 Query: 141 ALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPP 200 L++ +A + G N + + ILG G+ A+D A +L Sbjct: 128 KLELE--------NAEQYEGK-NLH-YFVDDLQKFAGRRVAILGGGDSAVDWALML---- 173 Query: 201 DHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADF 260 + K V I+ RR + E ++ P + PA+ Sbjct: 174 -----------------EPIAKEVSIIHRRDKFRAHEHSVENLHASKVNVLTPFV-PAEL 215 Query: 261 LGLQDRIKE 269 +G +D+I++ Sbjct: 216 IG-EDKIEQ 223 >2CDU-A nrPDB Length = 452 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 64/172 (37%), Gaps = 26/172 (15%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEK-----QLVPFGLVRFGVAPDHPEVKNVI 94 ++ VVG AG + + + H A V YE L + G + + + + Sbjct: 2 KVIVVGCTHAGTFAVKQTIADHPDADVTAYEMNDNISFLSCGIALYLGKEIKNNDPRGLF 61 Query: 95 NTFTQTARSDRCAFYGNVEV------GRDVTVQEL------QDAYHAVVLSYGAEDHQAL 142 + + + +V + + V++L +AY ++++ G+ Sbjct: 62 YSSPEELSNLGANVQMRHQVTNVDPETKTIKVKDLITNEEKTEAYDKLIMTTGS-KPTVP 120 Query: 143 DIPGEELPGVFSARAFVGWYNGLPENRELAPDLS-CDTAVILGQGNVALDVA 193 IPG + V+ + + + ++L + T I+G G + ++A Sbjct: 121 PIPGIDSSRVYLCKNY-------NDAKKLFEEAPKAKTITIIGSGYIGAELA 165 >4IV9-A nrPDB Length = 557 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 32 FSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLV 79 +S TP++ +VG+G +G A LL+ V +YE + G V Sbjct: 32 YSAGTPTPRVAIVGAGISGLVAATELLRAG-VKDVVLYESRDRIGGRV 78 >4CBQ-A nrPDB Length = 314 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 42/250 (16%), Positives = 82/250 (32%), Gaps = 62/250 (24%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFG------VAPDHP-EVKNV 93 + ++GSGPA A +L + S +YE + G+ G + + P + Sbjct: 7 VVIIGSGPAAHTAAIYLGR--SSLKPVMYEGFMA-GGVAAGGQLTTTTIIENFPGFPNGI 63 Query: 94 INTFTQTARSDRCAFYGNVEVGRDV-------TVQELQDAY------HAVVLSYGAEDHQ 140 + YG + + +L +V+++ GA + Sbjct: 64 DGNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKLFTEEGKEVLTKSVIIATGA-TAK 122 Query: 141 ALDIPGEELPGVFSARAFVGWYNGLPE---NRELAPDLSCDTAVILGQGNVALDVARILL 197 + +PGE+ W NG+ P +++G G+ A++ A Sbjct: 123 RMHVPGED----------KYWQNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEA---- 168 Query: 198 TPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDP 257 HL K V I+ RR + + T++E ++ P + + Sbjct: 169 ---LHLTKYG--------------SKVIILHRRDAFRASKTMQE--RVLNHPKIEVIWNS 209 Query: 258 --ADFLGLQD 265 + G D Sbjct: 210 ELVELEGDGD 219 >3D8X-A nrPDB Length = 326 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 40/250 (16%), Positives = 79/250 (31%), Gaps = 56/250 (22%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA--------------P 85 ++ ++GSGPA A +L + + +YE G++ G+A P Sbjct: 12 KVTIIGSGPAAHTAAIYLARAEIKP--ILYE------GMMANGIAAGGQLTTTTEIENFP 63 Query: 86 DHP---EVKNVINTFTQTARSDRCAFYGNVE--VGRDVTVQELQDAY---------HAVV 131 P +++ + + V +L + A++ Sbjct: 64 GFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAII 123 Query: 132 LSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALD 191 L+ GA + + +PGEE + + P ++G G+ A + Sbjct: 124 LATGA-SAKRMHLPGEE-------TYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACE 175 Query: 192 VARIL---------LTPPDHLEKTDITEAALGALRQSRVKTVWIVGRR---GPLQVAFTI 239 A+ L L DHL + I + + + + G L A I Sbjct: 176 EAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRI 235 Query: 240 KELREMIQLP 249 K ++ + Sbjct: 236 KNTKKNEETD 245 >2JB2-A nrPDB Length = 489 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLV 79 + V+G GPAG +A L K + V + E + P G V Sbjct: 14 VVVLGGGPAGLCSAFELQKAGYK--VTVLEARTRPGGRV 50 >3F8P-A nrPDB Length = 323 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 39/194 (20%), Positives = 69/194 (35%), Gaps = 40/194 (20%) Query: 19 LPPSRSIQNFGQHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGL 78 LP + S++ G+ F + +VG GPA + A + ++ + V I E P G Sbjct: 4 LPRTTSVKP-GEKFD-------VIIVGLGPAAYGAALYSARYMLKTLV-IGE---TPGGQ 51 Query: 79 VR-FGVAPDHPEVKNV-----INTFTQTARSDRCAFYGNVE----------VGRDVTVQE 122 + G+ D+ + + I F + ++ V + E Sbjct: 52 LTEAGIVDDYLGLIEIQASDMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGE 111 Query: 123 LQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVI 182 +V+L G + L +PGE+ F G + P + Sbjct: 112 F--KADSVILGIGV-KRRKLGVPGEQ--------EFAGRGISYCSVCDA-PLFKNRVVAV 159 Query: 183 LGQGNVALDVARIL 196 +G G+ AL+ A IL Sbjct: 160 IGGGDSALEGAEIL 173 >4GCM-A nrPDB Length = 312 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 42/263 (15%), Positives = 96/263 (36%), Gaps = 50/263 (19%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA----PDHPEVK--NVI 94 I ++G+GPAG A + + + + + E+ +P G + P + ++ Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKT--VMIER-GIPGGQMANTEEVENFPGFEMITGPDLS 65 Query: 95 NTFTQTARSDRCAF-YGNVEVGRD------VTVQELQDAYHAVVLSYGAEDHQALDIPGE 147 + A+ + YG+++ D + + AV+++ GAE ++ + +PGE Sbjct: 66 TKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAE-YKKIGVPGE 124 Query: 148 -ELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVAL----------DVARIL 196 EL G ++ +G ++G G+ A+ D I+ Sbjct: 125 QELGG--RGVSYCAVCDG--------AFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIV 174 Query: 197 LTPPDHLEKTDITEAALGALRQSRVKTVWIV------GRRGPLQVAFTIKELREMIQLPG 250 + + + + A + + + + G+ G + + T E + G Sbjct: 175 HRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADG 234 Query: 251 T------RPMLDPADFLGLQDRI 267 +P+ P LG+ + + Sbjct: 235 VFIYIGMKPLTAPFKDLGITNDV 257 >1XHC-A nrPDB Length = 367 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 12/117 (10%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPF------GLVRFGVAPDHPEVKNV 93 ++ +VG+GP GF A+ L + V + +K+ VP+ G P + Sbjct: 10 KVVIVGNGPGGFELAKQLSQ---TYEVTVIDKEPVPYYSKPMLSHYIAGFIPRNRLFPYS 66 Query: 94 INTFTQTARSDRCAFYGNVE-VGRDVTVQELQD-AYHAVVLSYGAEDHQALDIPGEE 148 ++ + + R A + GR V + E + Y +VL+ GA + I G+E Sbjct: 67 LDWYRKRGIEIRLAEEAKLIDRGRKVVITEKGEVPYDTLVLATGA-RAREPQIKGKE 122 >6BWT-A nrPDB Length = 319 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 33/169 (19%), Positives = 62/169 (36%), Gaps = 29/169 (17%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGV-------APDHPEVKN 92 ++ ++GSGPAG+ A + + + + V I P G + PD Sbjct: 9 KLIILGSGPAGYTAAIYAARANLKP-VIITGM--QPGGQLTTTTDVYNWPGEPDGIMGPE 65 Query: 93 VINTFTQTARSDRCAFYGNVEVGRDVT------VQELQDAY--HAVVLSYGAEDHQALDI 144 ++ + A + D+ V E+ + Y ++++ GA + L Sbjct: 66 LMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVGEV-EQYTCDTLIIATGA-TAKYL-- 121 Query: 145 PGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVA 193 G+ S F+G + + D AV+ G GN A++ A Sbjct: 122 ------GLESEEKFMGKGVSACATCDGFFYKNKDVAVV-GGGNTAVEEA 163 >4EMJ-A nrPDB Length = 410 Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 33/165 (20%), Positives = 65/165 (39%), Gaps = 16/165 (9%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIY-EKQLVPFGL-VRFGVAPDHPEVKNVINTFT 98 + ++G+G GF TAQ L + + ++ +P+ D + I Sbjct: 5 VAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPYDRPSLSKAVLDGSLERPPILAEA 64 Query: 99 QTARSDRCAFYGNVEVG------RDVTVQE-LQDAYHAVVLSYGAEDHQALDIPGEELPG 151 R EV R +++ + + A+V++ G+ + + +PG +LPG Sbjct: 65 DWYGEARIDMLTGPEVTALDVQTRTISLDDGTTLSADAIVIATGS-RARTMALPGSQLPG 123 Query: 152 VFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARIL 196 V + R + G L ++ S +I+G G + +VA Sbjct: 124 VVTLRTY-GDVQVLRDSW-----TSATRLLIVGGGLIGCEVATTA 162 >3RHA-A nrPDB Length = 482 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 19/43 (44%), Gaps = 2/43 (4%) Query: 35 QEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFG 77 Q + +VG+GP+G A+ L K V + E + G Sbjct: 4 QNLDRDVVIVGAGPSGLTAARELKKAG--LSVAVLEARDRVGG 44 >4JDR-A nrPDB Length = 474 Score = 37.0 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 33/93 (35%), Gaps = 7/93 (7%) Query: 34 TQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGL-VRFGVAPDHPE--V 90 + E Q+ V+G+GPAG+ A I E+ G+ + G P V Sbjct: 2 STEIKTQVVVLGAGPAGYSAAFRCADLG--LETVIVERYNTLGGVCLNVGCIPSKALLHV 59 Query: 91 KNVINTFTQTARSDRCAF-YGNVEVGRDVTVQE 122 VI + F ++ + T +E Sbjct: 60 AKVIE-EAKALAEHGIVFGEPKTDIDKIRTWKE 91 >5XHU-A nrPDB Length = 329 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 56/169 (33%), Gaps = 23/169 (13%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNV------- 93 + ++G GP G +TA + + V E G V P+ ++++ Sbjct: 5 VTIIGGGPIGLFTAFYCGMRELKTKV--IEFLPKLGGKVSL-FFPE-KIIRDIGGIPGIA 60 Query: 94 INTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALD---IPGEELP 150 + + F ++ + + VT E D ++ G+E + I + Sbjct: 61 GKQLIEQLKEQAATFDPDIVLNQRVTGFERLD--DGTIVLTGSEGKKHYTRTVILACGM- 117 Query: 151 GVFSARAF----VGWYNG--LPENRELAPDLSCDTAVILGQGNVALDVA 193 G F Y G L E VI G G+ A+D A Sbjct: 118 GTLEVNEFDSEDAARYAGKNLHYGVEKLDAFKGKRVVISGGGDTAVDWA 166 >1F8S-A nrPDB Length = 498 Score = 36.2 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 17/40 (42%), Gaps = 2/40 (5%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVR 80 + +VG+G AG A L V + E P G VR Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGH--QVTVLEASERPGGRVR 73 >2A87-A nrPDB Length = 335 Score = 36.2 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 59/174 (33%), Gaps = 30/174 (17%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA---PDHP-------EV 90 + V+GSGPAG+ A + + V +E L+ P + Sbjct: 17 VIVIGSGPAGYTAALYAARAQLAPLV--FEGTSFGGALMTTTDVENYPGFRNGITGPELM 74 Query: 91 KNVINTFTQTARSDR------CAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDI 144 + + R + +G ++ Q + AV+L+ GA + L + Sbjct: 75 DEMREQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRAR--AVILAMGA-AARYLQV 131 Query: 145 PGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLT 198 PGE+ +G + D A ++G G+ A++ A L Sbjct: 132 PGEQ--------ELLGRGVSSCATCDGFFFRDQDIA-VIGGGDSAMEEATFLTR 176 >6GAR-A nrPDB Length = 349 Score = 35.9 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 55/189 (29%), Gaps = 52/189 (27%) Query: 35 QEQTPQICVVGSGPAGFYTA--QHLLKHHSRAHVDIYEKQLVPFGLV----------RFG 82 +E+ + V+G GPAG Y+A L + I E G + G Sbjct: 3 REELFDVTVIGGGPAGLYSAFYSGLREM----RTKIIEFHPHLGGKIHVYPEKMIWDVGG 58 Query: 83 VAP--DHPEVKNVINTFTQTARSDRCAFYGNVEVG----------------RDVTVQELQ 124 + P ++ ++ F V + + T +E Sbjct: 59 LLPVTGDKLIEQLVQQ--------GLTFKPEVVLDTKVESIIRNQDGTFTLKTSTGEEHF 110 Query: 125 DAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILG 184 V G Q L I G A F + L + T +I G Sbjct: 111 SKTVIVATGSGILKPQKLSIEG--------AERF--EVSNLNYTVKSLKRFKGKTVIISG 160 Query: 185 QGNVALDVA 193 GN A+D A Sbjct: 161 GGNSAVDWA 169 >3OC4-A nrPDB Length = 452 Score = 35.5 bits (80), Expect = 0.049, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 27/74 (36%), Gaps = 11/74 (14%) Query: 36 EQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVIN 95 E + + V+G+GP G L+K V ++E + P + K ++ Sbjct: 145 ENSQTVAVIGAGPIGMEAIDFLVKMKKT--VHVFESLEN--------LLPKY-FDKEMVA 193 Query: 96 TFTQTARSDRCAFY 109 ++ F+ Sbjct: 194 EVQKSLEKQAVIFH 207 >3C4A-A nrPDB Length = 381 Score = 35.5 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 4/53 (7%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVP----FGLVRFGVAPDHP 88 +I V+G+GPAG A L + +DI EK +G+V G HP Sbjct: 2 KILVIGAGPAGLVFASQLKQARPLWAIDIVEKNDEQEVLGWGVVLPGRPGQHP 54 >6DU7-A nrPDB Length = 448 Score = 35.5 bits (80), Expect = 0.051, Method: Composition-based stats. Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 17/91 (18%) Query: 109 YGNVEVGRDVTV-QELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPE 167 + V+V EL A H +V++ GA +IPG EL G S+ W LPE Sbjct: 113 HAEFVDSHTVSVNGELIRAKH-IVIATGAH-PSIPNIPGAELGG--SSDDVFAW-EELPE 167 Query: 168 NRELAPDLSCDTAVILGQGNVALDVARILLT 198 + ILG G +A+++A +L T Sbjct: 168 -----------SVAILGAGYIAVELAGVLHT 187 >5ZBC-A nrPDB Length = 451 Score = 35.5 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 33 STQEQTPQICVVGSGPAGFYTAQHLLK--HHSRAHVDIYEKQLVPFGLVRF 81 S + + IC+VG+G +G A HLL + I++ Q G +R Sbjct: 19 SHMKHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRS 69 >4Y4M-A nrPDB Length = 290 Score = 35.5 bits (80), Expect = 0.060, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 19/31 (61%), Gaps = 2/31 (6%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEK 71 + +VG+GP+G A++L K + V + E+ Sbjct: 62 VVIVGAGPSGLTCARYLAKEGFK--VVVLER 90 >1VDC-A nrPDB Length = 333 Score = 35.1 bits (79), Expect = 0.064, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 60/173 (34%), Gaps = 26/173 (15%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQL----VPFGLVRFGVA----PDHP--- 88 ++C+VGSGPA A + + + ++E + P G + P P Sbjct: 10 RLCIVGSGPAAHTAAIYAARAELKP--LLFEGWMANDIAPGGQLTTTTDVENFPGFPEGI 67 Query: 89 EVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQD-------AYHAVVLSYGAEDHQA 141 + + F + + + D + + + AV+L+ GA + Sbjct: 68 LGVELTDKFRKQSERFGTTIFTETVTKVDFSSKPFKLFTDSKAILADAVILAIGAVAKRL 127 Query: 142 LDI-PGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVA 193 + GE L G ++ + AP ++G G+ A++ A Sbjct: 128 SFVGSGEVLGGFWNRG-----ISACAVCDGAAPIFRNKPLAVIGGGDSAMEEA 175 >3ISH-A nrPDB Length = 311 Score = 35.1 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 59/167 (35%), Gaps = 27/167 (16%) Query: 42 CVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVR-FGVAPDHPEVKNVIN--TFT 98 ++G GPAG + + + V ++EK +P G + ++P VK V++ F Sbjct: 5 AIIGGGPAGLSAGLYATRGGVKNAV-LFEK-GMPGGQITGSSEIENYPGVKEVVSGLDFM 62 Query: 99 QTARSDRCAFYGNVEV-------GRDVTVQELQD-----AYHAVVLSYGAEDHQALDIPG 146 Q + F E+ +D L + +V+++ G + I G Sbjct: 63 QPWQEQCFRFGLKHEMTAVQRVSKKDSHFVILAEDGKTFEAKSVIIATG-GSPKRTGIKG 121 Query: 147 EELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVA 193 E + G + +LG G+ A++ A Sbjct: 122 ES--------EYWGKGVSTCATCDGFF-YKNKEVAVLGGGDTAVEEA 159 >5TWC-A nrPDB Length = 344 Score = 34.7 bits (78), Expect = 0.085, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 68/205 (33%), Gaps = 56/205 (27%) Query: 41 ICVVGSGPAGFYTA--QHLLKHHSRAHVDIYEKQLVPFGLVRF----------GVAPD-- 86 + ++G GP+G Y + L V + + Q G +R G+AP Sbjct: 4 VTIIGGGPSGLYASFYAGLRDMS----VRLIDVQSELGGKMRIYPEKIIWDIGGIAPKPC 59 Query: 87 HPEVKNVINTFTQTARSDRCAFYGNVEVG-RDVTVQELQDAYHAVVLSYG---------- 135 H +K+ I F V + R V +++ + + V G Sbjct: 60 HEILKDTIKQ--------GLYFKPEVHLNERVVDIRKKAERHFEVETEAGEIYTSKAVII 111 Query: 136 -----AEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVAL 190 + + LD+ G E + + V Y + +I G GN AL Sbjct: 112 AIGAGIINPKQLDVKGVERYQLTNLHYVVQSYRRFKDKD----------VLISGGGNTAL 161 Query: 191 ----DVARILLTPPDHLEKTDITEA 211 D+A+I + K D++ Sbjct: 162 DWAHDIAKIAKSVTVVYRKEDVSGH 186 >2VOU-A nrPDB Length = 397 Score = 34.7 bits (78), Expect = 0.085, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 23/63 (36%), Gaps = 2/63 (3%) Query: 38 TPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTF 97 T +I VVG +G A L VD+YE+ P G+ V ++ Sbjct: 5 TDRIAVVGGSISGLTAALMLRDAG--VDVDVYERSPQPLSGFGTGIVVQPELVHYLLEQG 62 Query: 98 TQT 100 + Sbjct: 63 VEL 65 >4Y4N-A nrPDB Length = 286 Score = 34.7 bits (78), Expect = 0.090, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 18/31 (58%), Gaps = 2/31 (6%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEK 71 + +VG GP+G A+++ K + V + E+ Sbjct: 55 VAIVGGGPSGLTAARYIAKEGYK--VVVLER 83 >5UWY-A nrPDB Length = 308 Score = 34.7 bits (78), Expect = 0.093, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 17/119 (14%) Query: 43 VVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLV--RFGVA--PDHPEVK--NVINT 96 ++GSGPAG A L S V I E Q P G + F + P + + + Sbjct: 9 IIGSGPAGMTAA--LYAARSNLSVAIIE-QGAPGGQMNNTFDIENYPGYDHISGPELAMK 65 Query: 97 FTQTARSDRC-AFYG------NVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEE 148 + YG N + V ++ V+++ GA ++ L +PGEE Sbjct: 66 MYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKTVIIATGA-KYRVLGVPGEE 123 >2TMD-A nrPDB Length = 729 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 10/113 (8%) Query: 30 QHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVD-----IYEKQLVPFGLVRFGVA 84 + F + + +VG+GP+G A+ L++ H+ I L G Sbjct: 381 EKFRQTKNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAALPGLGEW 440 Query: 85 PDHPEVKNV-INTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGA 136 H + + I + + + A DV LQ V+++ GA Sbjct: 441 SYHRDYRETQITKLLKKNKESQLALGQKPMTADDV----LQYGADKVIIATGA 489 >3WE0-A nrPDB Length = 580 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 20/43 (46%), Gaps = 3/43 (6%) Query: 39 PQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRF 81 ++ +VG+G AG A L+K + V YE G +R Sbjct: 66 EEVAIVGAGIAGLVAAYELMKLGLKPVV--YEA-SKMGGRLRS 105 >5U63-A nrPDB Length = 321 Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 26/171 (15%), Positives = 60/171 (35%), Gaps = 27/171 (15%) Query: 37 QTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRF-----GVAPDHPEV- 90 + ++ ++GSGPAG+ A + + + + + L G + D Sbjct: 8 KHAKLLILGSGPAGYTAAIYAARANLKP---VLVTGLQQGGQLTTTDEIENWPGDFEMTT 64 Query: 91 -KNVINTFTQTARSDRCAFYGNVEVGRDVT------VQELQD-AYHAVVLSYGAEDHQAL 142 ++ Q A + D++ ++Q+ A++++ GA + + Sbjct: 65 GSGLMQRMLQHAEKFETEIVFDHINRVDLSSRPFKLFGDVQNFTCDALIIATGA-SARYI 123 Query: 143 DIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVA 193 +P EE + G + + ++G GN A++ A Sbjct: 124 GLPSEE--------NYKGRGVSACATCDGFFYRNKPVG-VIGGGNTAVEEA 165 >3LXD-A nrPDB Length = 415 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 30/200 (15%), Positives = 57/200 (28%), Gaps = 29/200 (14%) Query: 76 FGLVRFGVAPDHP-----EVKNVINTF----------TQTARSDRCAFYGNVEV------ 114 ++ G P+ P K + Q EV Sbjct: 35 GRVLVIGREPEIPYERPPLSKEYLAREKTFERICIRPAQFWEDKAVEMKLGAEVVSLDPA 94 Query: 115 GRDVTVQELQD-AYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAP 173 V + + Y ++ + G D + L G +L GV + + Sbjct: 95 AHTVKLGDGSAIEYGKLIWATG-GDPRRLSCVGADLAGVHAV-----RTKEDADRLMAEL 148 Query: 174 DLSCDTAVILGQGNVALDVARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPL 233 D AV++G G + L+ A +L ++ + L + + + R Sbjct: 149 DAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAH- 207 Query: 234 QVAFTIKELREMIQLPGTRP 253 V + I+ GT+ Sbjct: 208 GVDLRTGAAMDCIEGDGTKV 227 >1SEZ-A nrPDB Length = 504 Score = 33.6 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRF 81 ++ V+G+G +G A L H +V ++E + G +R Sbjct: 15 RVAVIGAGVSGLAAAYKLKIHG--LNVTVFEAEGKAGGKLRS 54 >3FPZ-A nrPDB Length = 326 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 42/275 (15%), Positives = 84/275 (30%), Gaps = 39/275 (14%) Query: 6 WRWWPWSSWTRTRLPPSRSIQNFGQHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAH 65 +++ P T +R SR ++ + F+ + + +VG+G +G A + K+ Sbjct: 38 FKFAPIRESTVSRAMTSRYFKDLDK-FAVSD----VIIVGAGSSGLSAAYVIAKNRPDLK 92 Query: 66 VDIYEKQLVPFGLVRFGVAPDHPEVKNVINT-----FTQTARSDRCAFYGNVEVGRDVTV 120 V I E + P G G ++ F Q G+ V + Sbjct: 93 VCIIESSVAPGG----GSWLGGQLFSAMVMRKPAHLFLQELEIP-YEDEGDYVVVKHA-- 145 Query: 121 QELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTA 180 A+ +S + L +P +L V A Sbjct: 146 --------ALFISTVL--SKVLQLPNVKLFNATCVEDLVTR--------PPTEKGEVTVA 187 Query: 181 VILGQGNVALDVARILLT-PPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQV--AF 237 ++ + + P+ +E L Q + G GP A Sbjct: 188 GVVTNWTLVTQAHGTQCSMDPNVIELAGYKNDGTRDLSQKHGVILSTTGHDGPFGAFCAK 247 Query: 238 TIKELREMIQLPGTRPM-LDPADFLGLQDRIKEAA 271 I ++ + +L G + + ++ A+ + A Sbjct: 248 RIVDIDQNQKLGGMKGLDMNHAEHDVVIHSGAYAG 282 >4FX9-A nrPDB Length = 453 Score = 33.2 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 58/302 (19%), Positives = 97/302 (32%), Gaps = 37/302 (12%) Query: 35 QEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQ----LVPFGL--VRFGVAPDHP 88 + ++ ++G G AG A + + V ++E P G+ V G++ Sbjct: 3 ENMKKKVVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVSHAPCGIPYVVEGLSTPDK 62 Query: 89 EVKNVINTFTQTARSDRCAFYGNVEVGRDVT--------VQELQDAYHAVVLSYGAEDHQ 140 + F + + N EV T E + +V + GA Q Sbjct: 63 LMYYPPEVFIK---KRGIDLHLNAEVIEVDTGYVRVRENGGEKSYEWDYLVFANGA-SPQ 118 Query: 141 ALDIPGEELPGVFSA---------RAFVGWY---NGLPENRELAPDLSCDTAVILGQGNV 188 I G L GVF+A R ++ Y N + + G+ Sbjct: 119 VPAIEGVNLKGVFTADLPPDALAIREYMEKYKVENVVIIGGGYIGIEMAEAFAAQGKNVT 178 Query: 189 ALDVARILLTPPDHLEKTDITEAALGALRQSRVKTVW--IVGRRGPLQVAFTIKELRE-- 244 + +L E TDI E L R++ + I G +V E + Sbjct: 179 MIVRGERVLRRSFDKEVTDILEEKLKKHVNLRLQEITMKIEGEERVEKVVTDAGEYKAEL 238 Query: 245 MIQLPGTRPMLDPADFLGLQDRIKEAARP-RKRLMELLLRTATEKPGVEEAARRASASRA 303 +I G +P ++ A LG+ RI E M+ + V E + R Sbjct: 239 VILATGIKPNIELAKQLGV--RIGETGAIWTNEKMQTSVENVYAAGDVAETRHVITGRRV 296 Query: 304 WG 305 W Sbjct: 297 WV 298 >2CVJ-A nrPDB Length = 180 Score = 32.8 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 32/188 (17%), Positives = 54/188 (28%), Gaps = 26/188 (13%) Query: 41 ICVVGSGPAGFYTAQHLLKH--------HSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKN 92 + VVG GP+G A L + R+ V + GL+ D P + Sbjct: 4 VIVVGGGPSGLSAALFLARAGLKVLVLDGGRSKVKGVSRVPNYPGLL------DEPSGEE 57 Query: 93 VINTFTQTARSDRCAFYGNVEVGR-------DVTVQELQDAYHAVVLSYGAEDHQALDIP 145 ++ AR V G +V +E + ++L +D + Sbjct: 58 LLRRLEAHARRYGAEVRPGVVKGVRDMGGVFEVETEEGVEKAERLLLCT-HKDPTLPSLL 116 Query: 146 GEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARILLTPPDHLEK 205 G G + G + I+ G D A + + L Sbjct: 117 GLTRRGAYIDTDEGGRTSYPRVYAAGVARGKVPGHAIISAG----DGAYVAVHLVSDLRG 172 Query: 206 TDITEAAL 213 + AL Sbjct: 173 EPYKDHAL 180 >1RP0-A nrPDB Length = 284 Score = 32.8 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 42/126 (33%), Gaps = 13/126 (10%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQT 100 + VVG+G AG A + K + V I E+ + P G G +I Sbjct: 42 VVVVGAGSAGLSAAYEISK-NPNVQVAIIEQSVSPGG----GAWLGGQLFSAMI------ 90 Query: 101 ARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVG 160 R F + V D + + A+ S + L P +L +A + Sbjct: 91 VRKPAHLFLDEIGVAYDEQDTYVVVKHAALFTST--IMSKLLARPNVKLFNAVAAEDLIV 148 Query: 161 WYNGLP 166 N + Sbjct: 149 KGNRVG 154 >6GB2-BC nrPDB Length = 657 Score = 32.4 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 44/119 (36%), Gaps = 11/119 (9%) Query: 227 VGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAARPRKRLMELLLRTAT 286 VG G + +E+ E+ P R ++D + Q++ +E ++++ Sbjct: 346 VGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQE-------DLKIIEEKRK 398 Query: 287 EKPGVEEAARRASASRAW----GLRFFRSPQQVLPSPDGRRAAGIRLAVTRLEGIGEAT 341 E + AR W LRF +Q+ P +R + ++G + + Sbjct: 399 EHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGS 457 >4JNQ-A nrPDB Length = 345 Score = 32.0 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 46/127 (36%), Gaps = 19/127 (14%) Query: 26 QNFGQHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVA- 84 Q G TQ P + V+GSGPAG+ A + + + V L G + Sbjct: 15 QTQGPGSMTQRHAP-VIVIGSGPAGYTAAIYAARAMLKPVVI---AGLQQGGQLMITTDV 70 Query: 85 ---PDHPEVKN---VINTFTQTARSDRCAFYGNVEVGRDVTVQELQDA--------YHAV 130 P + E ++ + A + ++ + TV+ + A+ Sbjct: 71 ENYPGYAEPVQGPWMMEQMARQAENVGAQIVHDIITEVETTVRPFRLKGDSGTIYTCDAL 130 Query: 131 VLSYGAE 137 +++ GA+ Sbjct: 131 IIATGAQ 137 >4Q20-A nrPDB Length = 268 Score = 32.0 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 24/72 (33%) Query: 323 RAAGIRLAVTRLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVP 382 R G RLA T + A R P G L L + VPF + + Sbjct: 150 RGDGKRLAQTLDHLVENALRQTPPGGRVTLSARRALGEVRLDVSDTGRGVPFHVQAHIFD 209 Query: 383 NMEGRVVDVPGL 394 GR PGL Sbjct: 210 RFVGRDRGGPGL 221 >3UKH-A nrPDB Length = 519 Score = 31.6 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPD 86 + V+G+GP G A+ L + I + P GL V P+ Sbjct: 9 VLVIGAGPTGLGAAKRLNQI-DGPSWMIVDSNETPGGLASTDVTPE 53 >3NIX-A nrPDB Length = 421 Score = 31.6 bits (70), Expect = 0.73, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 35 QEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAP 85 Q + + V+G+GPAG A + K + V I EKQ P ++ + P Sbjct: 2 QREKVDVLVIGAGPAGTVAASLVNKSGFK--VKIVEKQKFPRFVIGESLLP 50 >1Q1R-A nrPDB Length = 431 Score = 31.6 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 30/89 (33%), Gaps = 4/89 (4%) Query: 126 AYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQ 185 Y +VL+ G + L + V A F ++ + V++G Sbjct: 102 DYDRLVLATG-GRPRPLPVAS---GAVGKANNFRYLRTLEDAECIRRQLIADNRLVVIGG 157 Query: 186 GNVALDVARILLTPPDHLEKTDITEAALG 214 G + L+VA + H+ D L Sbjct: 158 GYIGLEVAATAIKANMHVTLLDTAARVLE 186 >2R9Z-A nrPDB Length = 463 Score = 31.6 bits (70), Expect = 0.89, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 52/155 (33%), Gaps = 23/155 (14%) Query: 32 FSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYE-KQLVPFGLVRFGVAPDHPEV 90 F+ Q+Q ++ ++G+G G A L S V E + L F + ++ Sbjct: 160 FALQQQPKRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHA 219 Query: 91 KNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYG-AEDHQALDIPG--- 146 + + + G V +D T + + +V+ + G A + + L + Sbjct: 220 QGIETHLEFAVAALERDAQGTTLVAQDGT---RLEGFDSVIWAVGRAPNTRDLGLEAAGI 276 Query: 147 ---------------EELPGVFSARAFVGWYNGLP 166 +PGV++ G P Sbjct: 277 EVQSNGMVPTDAYQNTNVPGVYALGDITGRDQLTP 311 >4ZCC-A nrPDB Length = 336 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFG 77 I ++G+G AG AQ L V +++K G Sbjct: 5 IAIIGTGIAGLSAAQALTSAGH--QVHLFDKSRGSGG 39 >3K30-A nrPDB Length = 690 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 42/110 (38%), Gaps = 9/110 (8%) Query: 30 QHFSTQEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPE 89 + +E ++ VVG+GP+G A+ L V + E G V + Sbjct: 383 ERIRAKESDARVLVVGAGPSGLEAARALGVRGY--DVVLAEAGRDLGGRVTQ----ESAL 436 Query: 90 VKNVINTFTQTARSDRCAFYGNVEVGRD--VTVQELQD-AYHAVVLSYGA 136 + R A NVE+ R+ +T ++ + + V+ + GA Sbjct: 437 PGLSAWGRVKEYREAVLAELPNVEIYRESPMTGDDIVEFGFEHVITATGA 486 >3KKJ-A nrPDB Length = 336 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFG 77 I ++G+G AG AQ L V +++K G Sbjct: 5 IAIIGTGIAGLSAAQALTAAGH--QVHLFDKSRGSGG 39 >3HN2-A nrPDB Length = 312 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 20/54 (37%), Gaps = 4/54 (7%) Query: 40 QICVVGSGPAGFYTAQHLLKHHSRAHVDI---YEKQLVPFGLVRFGVAPDHPEV 90 +I +VG+G G Y L + H + YE GL F + D Sbjct: 4 RIAIVGAGALGLYYGALLQRSGEDVHFLLRRDYEAI-AGNGLKVFSINGDFTLP 56 >2GMH-A nrPDB Length = 584 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHVDI 68 + +VG+GPAG A L + ++ D+ Sbjct: 38 VVIVGAGPAGLSAATRLKQLAAQHEKDL 65 >4YWO-A nrPDB Length = 462 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 38/269 (14%), Positives = 82/269 (30%), Gaps = 41/269 (15%) Query: 35 QEQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGL-VRFGVAPDHPEVKNV 93 Q+ ++ ++G G AGF ++K + + + G V G P + + Sbjct: 12 QDPMHKLAIIGYGAAGF---AAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRML-YI 67 Query: 94 INTFTQTARSDRCAFYGN----------VEVGRDVTVQELQDAYHAVVLSYGAEDHQALD 143 + + Y V+ R ++L Y ++ + + + Sbjct: 68 AEIYKKAREVTGSEVYPPFSSFQEKDGLVQEMRKTKYEDLLSYYDVELIQ---GEARFIS 124 Query: 144 IPGEELPG-VFSARAFVGWYNGLP---------------ENRELAPDLSCDTAVILGQGN 187 ++ G V A FV P L+PD D+ ++G Sbjct: 125 PHAVKVNGQVIEAEKFVIATGSSPLIPRIPGLDKVGFWTNREALSPDRRIDSLAVIGGRA 184 Query: 188 VALDVARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQ---VAFTIKELRE 244 +AL+ A++ + + L + RR T ++E Sbjct: 185 LALEFAQMYSRMKVEVAILQRSP----VLIPDWEPEASVEARRIMENDGVAVVTGVNVKE 240 Query: 245 MIQLPGTRPMLDPADFLGLQDRIKEAARP 273 + + G + D + + + +P Sbjct: 241 VRKGAGKIVITDKGEVEADEILLATGRKP 269 >3L1R-A nrPDB Length = 478 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 39 PQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFG 77 P++ VVG+G +G A+ L + + I E G Sbjct: 5 PRVIVVGAGMSGISAAKRLSEAG-ITDLLILEATDHIGG 42 >5MOG-A nrPDB Length = 497 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 50/162 (30%), Gaps = 23/162 (14%) Query: 33 STQEQTP-QICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVR----------- 80 S Q P Q+ + G+G AG TA++L + + E + V G + Sbjct: 11 SEQPTKPLQVVIAGAGLAGLSTAKYLADAGHKP--ILLEARDVLGGKIAAWKDEDGDWYE 68 Query: 81 FGVAPDHPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGAEDHQ 140 G+ N+ N F + +DR + + + + + Sbjct: 69 TGLHIFFGAYPNIQNLFGELGINDRLQWKEHSMIFAMPNKPGEFSRFDF---------PE 119 Query: 141 ALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVI 182 L P + + + W + L P + A + Sbjct: 120 TLPAPLNGIWAILRNNEMLTWPEKVKFALGLLPAMVGGQAYV 161 >6DLL-A nrPDB Length = 398 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 13/24 (54%) Query: 38 TPQICVVGSGPAGFYTAQHLLKHH 61 Q+ ++G+GP+G Q L K Sbjct: 5 KTQVAIIGAGPSGLLLGQLLHKAG 28 >1DOD-A nrPDB Length = 394 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 13/24 (54%) Query: 38 TPQICVVGSGPAGFYTAQHLLKHH 61 Q+ ++G+GP+G Q L K Sbjct: 2 KTQVAIIGAGPSGLLLGQLLHKAG 25 >1FCD-A nrPDB Length = 401 Score = 29.3 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 46/143 (32%), Gaps = 15/143 (10%) Query: 310 RSPQQVLPSPDGRRAAGIRLAVTRLEGIGEATRAVPTGDVEDLPCGLVLSSIGYKSRPID 369 R + + DG RA GI++ GI + V T + GY + Sbjct: 53 RKLESIKHGYDGLRAHGIQVVHDSATGIDPDKKLVKTAGGAEF---------GYDRCVVA 103 Query: 370 PSVPFDPKLGVVPNMEGRVVDVPGLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAG 429 P + + +EG + W T ++ + D G +++ A Sbjct: 104 PGIEL-----IYDKIEGYSEEAAAKLPHAWKAGEQTAILRKQLEDMADGGTVVIAPPAAP 158 Query: 430 -HLPSGPRPGSAFIKALLDSRGV 451 P GP ++ + L + Sbjct: 159 FRCPPGPYERASQVAYYLKAHKP 181 >5YFP-H nrPDB Length = 753 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 25/68 (36%), Gaps = 7/68 (10%) Query: 274 RKRLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVL-------PSPDGRRAAG 326 RL++++ + + + S R+ +S QQ P+ + RR+ G Sbjct: 433 CSRLLDVIRKAKDDLCDIFHVEEENSKRIRESFRYLQSTQQTPGRENNRSPNKNKRRSMG 492 Query: 327 IRLAVTRL 334 + R Sbjct: 493 GSITPGRN 500 >4NTC-A nrPDB Length = 335 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 15/26 (57%) Query: 41 ICVVGSGPAGFYTAQHLLKHHSRAHV 66 + ++G+GPAG TA L + A V Sbjct: 17 VLIIGAGPAGLSTATGLARQLHTAVV 42 >2REM-A nrPDB Length = 193 Score = 28.9 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 14/35 (40%) Query: 52 YTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPD 86 Y A +L R+H ++E + V PD Sbjct: 78 YLAADVLGVAKRSHTAMFEAIHEKGSVPIQNVGPD 112 >2YQU-A nrPDB Length = 455 Score = 28.9 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 38/264 (14%), Positives = 79/264 (29%), Gaps = 70/264 (26%) Query: 43 VVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGL-VRFGVAPDHPEVKNVINTFTQTA 101 V+G+GP G+ A + V + EK+ G +R G P ++ + Sbjct: 6 VIGAGPGGYVAAIRAAQLG--MKVGVVEKEKALGGTCLRVGCIPSKALLETTERIYEAKK 63 Query: 102 RSDRCAFYG---------------------------------------NVEVGRDVTVQE 122 G R V V+E Sbjct: 64 GLLGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFLSERKVLVEE 123 Query: 123 LQDAYHA--VVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTA 180 + A ++++ G+ + V ++ + P++ Sbjct: 124 TGEELEARYILIATGS-APLIPPWAQVDYERVVTSTEALS-----------FPEVP-KRL 170 Query: 181 VILGQGNVALD---------VARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRG 231 +++G G + L+ I+L D + T E + A R + + + I R Sbjct: 171 IVVGGGVIGLELGVVWHRLGAEVIVLEYMDRILPTMDLEVSRAAERVFKKQGLTI---RT 227 Query: 232 PLQVAFTIKELREM-IQLPGTRPM 254 ++V + E + ++L G + Sbjct: 228 GVRVTAVVPEAKGARVELEGGEVL 251 >1WDI-A nrPDB Length = 345 Score = 28.2 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 48/114 (42%), Gaps = 15/114 (13%) Query: 212 ALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQL--PGTRPMLDPADFLGLQDRIKE 269 A + + + +V R GP +VA K +R++ + PG + + + + + Sbjct: 17 AQEGVEPRDMARLMVVYREGPFRVAH--KRVRDLPEFLRPGDVLVFNESKVIPAR---LL 71 Query: 270 AARPRKRLMELLLRTATEKPGVEEA----ARRASASRAWGLRFFRSPQQVLPSP 319 A +P +E+LL PG+ EA AR+A SP+ + P P Sbjct: 72 ARKPTGGKVEILL-VRERSPGLWEALLGPARKAPPGTRL---LLLSPKDLAPVP 121 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.129 0.354 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,323,446 Number of Sequences: 36641 Number of extensions: 730270 Number of successful extensions: 2554 Number of sequences better than 10.0: 91 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 2444 Number of HSP's gapped (non-prelim): 128 length of query: 492 length of database: 10,336,785 effective HSP length: 101 effective length of query: 391 effective length of database: 6,636,044 effective search space: 2594693204 effective search space used: 2594693204 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)