BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07872 (661 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1IS2-A nrPDB 1322 0.0 2FON-A nrPDB 572 e-163 1W07-A nrPDB 557 e-159 5K3G-A nrPDB 544 e-155 5K3J-A nrPDB 525 e-149 5Y9D-A nrPDB 348 4e-96 5YS9-A nrPDB 320 1e-87 1JQI-A nrPDB 64 2e-10 4M9A-A nrPDB 59 5e-09 2VIG-A nrPDB 55 8e-08 4L1F-A nrPDB 55 8e-08 1UKW-A nrPDB 55 1e-07 5OL2-C nrPDB 51 1e-06 3MPI-A nrPDB 50 4e-06 4N5F-A nrPDB 49 5e-06 2IX5-A nrPDB 45 8e-05 4HR3-A nrPDB 45 1e-04 6ES9-A nrPDB 44 2e-04 1BUC-A nrPDB 44 2e-04 2PG0-A nrPDB 44 2e-04 3B96-A nrPDB 44 3e-04 3MDE-A nrPDB 42 7e-04 4U83-A nrPDB 42 8e-04 6FAH-C nrPDB 42 0.001 2Z1Q-A nrPDB 42 0.001 2A1T-A nrPDB 40 0.002 3R7K-A nrPDB 40 0.004 4KTO-A nrPDB 39 0.005 3OWA-A nrPDB 39 0.006 3SWO-A nrPDB 38 0.016 3SF6-A nrPDB 38 0.017 5LNX-A nrPDB 37 0.022 1SIR-A nrPDB 37 0.025 2DVL-A nrPDB 36 0.042 2JIF-A nrPDB 36 0.045 3P4T-A nrPDB 36 0.057 3PFD-A nrPDB 35 0.070 4IV6-A nrPDB 35 0.11 1V2Y-A nrPDB 32 1.1 4LD0-A nrPDB 32 1.2 3GNC-A nrPDB 32 1.3 3NF4-A nrPDB 31 1.6 3U33-A nrPDB 31 1.9 1SC7-A nrPDB 31 1.9 3JXA-A nrPDB 30 3.6 1FOK-A nrPDB 29 5.2 5EZ3-A nrPDB 29 7.8 >1IS2-A nrPDB Length = 661 Score = 1322 bits (3422), Expect = 0.0, Method: Compositional matrix adjust. Identities = 634/661 (95%), Positives = 642/661 (97%) Query: 1 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRY 60 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRY Sbjct: 1 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRY 60 Query: 61 EVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQ 120 EVAVKKSATMVKKMREYGISDPEEIMWFK EP+ L+ MF+PTLL+Q T QQ Sbjct: 61 EVAVKKSATMVKKMREYGISDPEEIMWFKNSVHRGHPEPLDLHLGMFLPTLLHQATAEQQ 120 Query: 121 EKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGL 180 E++ P+ L+I GTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGL Sbjct: 121 ERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGL 180 Query: 181 GKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYL 240 GKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYL Sbjct: 181 GKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYL 240 Query: 241 KMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 KMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA Sbjct: 241 KMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 Query: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG Sbjct: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 Query: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF Sbjct: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 Query: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSL 480 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSL Sbjct: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSL 480 Query: 481 EGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFS 540 EGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFS Sbjct: 481 EGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFS 540 Query: 541 DKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIR 600 DKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIR Sbjct: 541 DKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIR 600 Query: 601 PNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPLQSK 660 PNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPLQSK Sbjct: 601 PNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPLQSK 660 Query: 661 L 661 L Sbjct: 661 L 661 >2FON-A nrPDB Length = 683 Score = 572 bits (1473), Expect = e-163, Method: Compositional matrix adjust. Identities = 299/663 (45%), Positives = 422/663 (63%), Gaps = 25/663 (3%) Query: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 L ER A F+ + + + GS + I L+ +DP F E L R + ++ + Sbjct: 26 LADERKKAGFDVDEMKIVWAGSRHDFELTDRISKLVASDPGFSKEGRTMLPRKELFKNTL 85 Query: 65 KKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWM 124 +K+A K++ E +S E M + + F + L++ MFIP + QGT QQEKW+ Sbjct: 86 RKAAYAWKRIIELRLSQEEATMLRRYVDEPAFTD---LHWGMFIPAIKGQGTDKQQEKWL 142 Query: 125 RPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 + ++QIIG YAQTE+GHG++++GLETTAT+DP+T EF+++SPT+TS KWWPGGLGK S Sbjct: 143 PLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDEFVIHSPTLTSSKWWPGGLGKVS 202 Query: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLK 241 HA+V A+LIT G+ YG++ F+V +R + HKPLPG+TVGDIG KFG Y MDNG L Sbjct: 203 THAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGVTVGDIGMKFGNGAYNSMDNGVLS 262 Query: 242 MDNYRIPRENMLMKYAQVKPDGTYVKP-LSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 D+ RIPR+ MLM+ +QV +G YV+ + +L YGTMV+VR +V +A+ ++S+A IA Sbjct: 263 FDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGTMVYVRQSIVADASLAMSRAVCIA 322 Query: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 RYSAVRRQ + E Q++D++TQQ +LFPLLA+AYAF FVG ++K Y + + + Sbjct: 323 TRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTQRLA 382 Query: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 D S LPE HA TAGLK+ TT GIEECR CGGHGY SSG+P ++ + PACT+ Sbjct: 383 ANDFSTLPEAHACTAGLKSLTTSATADGIEECRKLCGGHGYLCSSGLPELFAVYVPACTY 442 Query: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLN---DLPSQRIQPQQVAVW--PTMV 475 EG+N V+ LQ ARFLMK Q+ +GK G VSY+ L R +Q W P+ V Sbjct: 443 EGDNVVLQLQVARFLMKTISQLGTGKKPVGTVSYMGRIEHLMQCRSDVKQAEDWLKPSAV 502 Query: 476 DINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVV 535 EA++ R+AR+ AKNL S +++E + + DLV A+ AHC +V Sbjct: 503 --------LEAFEARSARMSVACAKNL----SKFENQEEGFAELAADLVEAAVAHCQLIV 550 Query: 536 VKVFSDKLPK-IQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILE 594 V + +KL + I K V+ L LC +YSL+ + + GDFL IT Q S N ++ Sbjct: 551 VSKYIEKLQQNIPGKGVKQQLEVLCGIYSLFILHKHQGDFLGTGYITSKQGSLANDQLRA 610 Query: 595 LLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHL 654 L + +RPNAV+LVDAF++ D LGS+LGRYDGNVY L+E A K PLNK+++ + +H+++ Sbjct: 611 LYSQLRPNAVSLVDAFNYTDHYLGSILGRYDGNVYPKLYEAAWKDPLNKSDIADGFHEYI 670 Query: 655 KPL 657 +PL Sbjct: 671 RPL 673 >1W07-A nrPDB Length = 659 Score = 557 bits (1436), Expect = e-159, Method: Compositional matrix adjust. Identities = 301/671 (44%), Positives = 415/671 (61%), Gaps = 32/671 (4%) Query: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 L ER A F+ E + + GS I L+ +DP F+ + L+R + ++ + Sbjct: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 Query: 65 KKSATMVKKMREYGISDPEEIMWFKKLYLANFVEP---VGLNYSMFIPTLLNQGTTAQQE 121 +K A K++ E +++ E L +F++ V L++ MF+P + QGT QQ+ Sbjct: 67 RKCAHAFKRIIELRLNEEEAGR------LRHFIDQPAYVDLHWGMFVPAIKGQGTEEQQK 120 Query: 122 KWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLG 181 KW+ + ++QIIG YAQTE+GHG++++GLETTAT DPKT EF++++PT T+ KWWPGGLG Sbjct: 121 KWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDEFVIHTPTQTASKWWPGGLG 180 Query: 182 KTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNG 238 K S HA+V A+LIT G+ YG+H F+V +R + H PLP ITVGDIG K G Y MDNG Sbjct: 181 KVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNG 240 Query: 239 YLKMDNYRIPRENMLMKYAQVKPDGTYV-KPLSNKLTYGTMVFVRSFLVGNAAQSLSKAC 297 +L D+ RIPR+ MLM+ ++V +G YV + +L YGTMV+VR +V +A+ +LS+A Sbjct: 241 FLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAV 300 Query: 298 TIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINE 357 IA RYSAVRRQ E Q++D++TQQ +LFPLLA+AYAF FVG ++K Y + E Sbjct: 301 CIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTE 360 Query: 358 SIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPA 417 + D + LPE HA TAGLK+ TT GIEECR CGGHGY SG+P ++ + PA Sbjct: 361 RLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPA 420 Query: 418 CTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLN---DLPSQRIQPQQVAVW--P 472 CT+EG+N V+ LQ ARFLMK Q+ SGK+ G +Y+ L R Q+ W P Sbjct: 421 CTYEGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDWLNP 480 Query: 473 TMVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCH 532 +V EA++ RA R+ AKNL S +++E + DLV A+ AHC Sbjct: 481 DVV--------LEAFEARALRMAVTCAKNL----SKFENQEQGFQELLADLVEAAIAHCQ 528 Query: 533 YVVVKVFSDKLPK-IQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNAR 591 +VV F KL + I K V+ L NLC +Y+LY + + GDFL + IT Q S N + Sbjct: 529 LIVVSKFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQ 588 Query: 592 ILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYH 651 + L T +RPNAVALVDAF++ D L SVLGRYDGNVY LFE A K PLN + V + Y Sbjct: 589 LRSLYTQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQ 648 Query: 652 KHLKP-LQSKL 661 ++L+P LQ +L Sbjct: 649 EYLRPVLQQQL 659 >5K3G-A nrPDB Length = 684 Score = 544 bits (1401), Expect = e-155, Method: Compositional matrix adjust. Identities = 291/668 (43%), Positives = 416/668 (62%), Gaps = 21/668 (3%) Query: 2 NPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHE-DYNFLTRSQRY 60 NPDL ER +ATF+ + + G RRRREI + P+ ++TR ++ Sbjct: 13 NPDLTAERLTATFDTHAMAAQIYGGEMRARRRREITAKLAEIPELHDSMPLPYMTREEKI 72 Query: 61 EVAVKKSATMVKKMREYGISDPE---EIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTT 117 + +K + ++M E I DP E+ L P+ L+ MFIP L Q + Sbjct: 73 MESARKLTVLTQRMSE--IIDPTDAGELYHLNNEVLGIEGNPMALHGVMFIPALNAQASD 130 Query: 118 AQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWP 177 QQ KW+ + +IIGTYAQTEMGHGT+L+ LETTATYD TQEF+L++P +T++KWWP Sbjct: 131 EQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIGTQEFVLHTPKITALKWWP 190 Query: 178 GGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDN 237 G LGK+SN+A+V+A + +G+ +G H F+VP+R+ THKPLPGIT+GDIGPK Y +DN Sbjct: 191 GNLGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHKPLPGITIGDIGPKMAYNIVDN 250 Query: 238 GYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKAC 297 G+L +NYRIPR N+LM++ +V+ DGTY+KP K+ Y MV VRS+++ A LS A Sbjct: 251 GFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKINYSAMVHVRSYMLTGQAIMLSYAL 310 Query: 298 TIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINE 357 IA RYSAVRRQ +I ++EPE ++L++QTQQ++LFP +A AYAF F G + Y R+ + Sbjct: 311 NIATRYSAVRRQGQIDKNEPEVKVLEYQTQQHRLFPFIARAYAFQFAGAETVKLYERVLK 370 Query: 358 SIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPA 417 + G++S + +LHALT+GLK+ T GIE+ RMACGGHGYS +S I IY Sbjct: 371 EMKSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMACGGHGYSMASYISEIYGVAIGG 430 Query: 418 CTFEGENTVMMLQTARFLMKIYDQVRSGKL--VGGMVSYLNDLPSQRIQPQQVAVWPTMV 475 CT+EGEN VM+LQ AR+L+K V+SGK +G +V+YL R +P +++ Sbjct: 431 CTYEGENMVMLLQLARYLVKSAALVKSGKASQLGPLVAYL----GARSEPT------SLI 480 Query: 476 DINSLEGLTE---AYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCH 532 D G+TE ++ A R AA + + + +E+AWN +SV+L RAS H Sbjct: 481 DRVPNGGITEYIKTFQHIAKRQTLKAANKFFGLMENGEKREIAWNKSSVELNRASRLHTR 540 Query: 533 YVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARI 592 +V+ F+ ++ +I D ++ L +L L+ Y + LE ++ QL V ++ Sbjct: 541 LFIVEAFARRVNEIGDITIKEALSDLLHLHVNYELLDVATYALEDGFMSSTQLDYVRDQL 600 Query: 593 LELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHK 652 L IRPNAV+L+D+++F D L SVLGR DG+VYENLF+WAK+SPLNKT+V S Sbjct: 601 YFYLQKIRPNAVSLLDSWEFSDRELRSVLGRRDGHVYENLFKWAKESPLNKTDVLPSVDT 660 Query: 653 HLKPLQSK 660 +LKP+ K Sbjct: 661 YLKPMMEK 668 >5K3J-A nrPDB Length = 674 Score = 525 bits (1351), Expect = e-149, Method: Compositional matrix adjust. Identities = 282/667 (42%), Positives = 406/667 (60%), Gaps = 27/667 (4%) Query: 2 NPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQH-EDYNFLTRSQRY 60 NP+L +ER ATF+ + + ++ GS E RRRREI + + P+ + Y FLTR ++ Sbjct: 11 NPELLEERRMATFDTDKMAAVIYGSEEFARRRREITDAVSKIPELADIKPYPFLTREEKV 70 Query: 61 EVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFV-----EPVGLNYSMFIPTLLNQG 115 +K + + K + + D EE + L+L V P L+ ++FIPTL +Q Sbjct: 71 TEGTRKISILTKYLNQLIDRDNEE----ESLHLHREVIGYEGHPFALHDALFIPTLQSQA 126 Query: 116 TTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKW 175 + QQEKW+ ++ +IIG YAQTE+GHG++LR LETTA YD +QEF+L++PT T++KW Sbjct: 127 SDEQQEKWLERARRREIIGCYAQTELGHGSNLRNLETTAVYDIASQEFVLHTPTTTALKW 186 Query: 176 WPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEM 235 WPG LGK+ N+A+V+A+LI + YG H F+V +R+ TH PL G+TVGDIGPK + Sbjct: 187 WPGALGKSCNYALVVAELIIKRNNYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMNFNAA 246 Query: 236 DNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSK 295 DNGYL ++N R+PR N+LM++ +V+ DGTYVKP K+ Y MV +RS + L+ Sbjct: 247 DNGYLGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAKIGYSGMVKIRSQMAMEQGLFLAH 306 Query: 296 ACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRI 355 A TIA RYSAVRRQ + + E ++LD+QTQQ++LFP LA AYAF F G Y ++ Sbjct: 307 ALTIAARYSAVRRQGHLDDKQVEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQL 366 Query: 356 NESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFT 415 + + G+ S + +LHALT+GLK+ GIE+ RMACGGHGYS +S I +Y Sbjct: 367 LKDVDMGNTSGMADLHALTSGLKSVVAHETGEGIEQARMACGGHGYSMASYISVVYGIAI 426 Query: 416 PACTFEGENTVMMLQTARFLMKIYDQVRSGKL--VGGMVSYLNDLPSQRIQPQQVAVWPT 473 CT+ GEN VM+LQ AR+L+K + +++GK +G + SYL D + Sbjct: 427 GGCTYAGENMVMLLQLARYLVKSVELIKAGKAKKLGPVASYLADKSDE------------ 474 Query: 474 MVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHY 533 D+ SL G + ++ A R A + + +S+EVAWN ++V+L RAS H Sbjct: 475 -TDLTSLNGYVKMFENMARRQAWKATEKFLKLMESGESREVAWNKSAVELTRASRLHTRL 533 Query: 534 VVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARIL 593 +++ F ++ +I+D V+ VL +L L+ Y + LE ++ QL V ++ Sbjct: 534 FIIEAFMRRVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALE--FMSFTQLDYVRDQLY 591 Query: 594 ELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKH 653 L IRPNAV+LVD+F DM L SVLGR DG+VYENLF+WAK SPLN +V S K+ Sbjct: 592 LYLEKIRPNAVSLVDSFQISDMQLRSVLGRRDGHVYENLFKWAKSSPLNNADVLPSVEKY 651 Query: 654 LKPLQSK 660 LKP+ K Sbjct: 652 LKPMMEK 658 >5Y9D-A nrPDB Length = 709 Score = 348 bits (893), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 217/680 (31%), Positives = 349/680 (51%), Gaps = 43/680 (6%) Query: 4 DLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQ-HEDYNFLTRSQRYEV 62 ++ KER F +T+ L+G E T+ +I + I DP DY+ + R Sbjct: 32 EMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQAR--- 88 Query: 63 AVKKSATMVKKMREYGISDPEEI-MWFKKLYLANFVE-----PVGLNYSMFIPTLLNQGT 116 K++ V + Y ++D E++ +W +L+ V+ + ++ ++FI ++ GT Sbjct: 89 --KQTMERVAALSPYLVTDTEKLSLWRAQLH--GMVDMSTRTRLSIHNNLFIGSIRGSGT 144 Query: 117 TAQQEKWMRPSQEL--QIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIK 174 Q + W++ Q G +A TE+GHG++L+GLETTATYD + +FI+N+P + + K Sbjct: 145 PEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATK 204 Query: 175 WWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEE 234 WW GG TS H + A+LI G+ YG FVVP+R + H G+++GDIG K G + Sbjct: 205 WWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDG 264 Query: 235 MDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLS 294 +DNG+++ N RIPR+NMLM+YA+V G KP ++LTYG ++ R ++ ++ Sbjct: 265 VDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSK 324 Query: 295 KACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYL- 353 + TIA+RY+ VRRQ E +I+D+ Q +L PLLA YA ++T++ Sbjct: 325 RFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIE 384 Query: 354 ---RI-----NESIGQGDL----SELPELHALTAGLKAFTTWTANAGIEECRMACGGHGY 401 RI N+ + DL ++ EL A +AG+KAFTTW I+ECR ACGGHGY Sbjct: 385 TTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGY 444 Query: 402 SHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLP-- 459 S +G Y + CT+EG+N V+ L R L++ Q+ +GK VG + Y+ D Sbjct: 445 SGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKI 504 Query: 460 SQRIQ--PQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWN 517 SQ Q P++ + P E L EA++ A+R + + + + + A+ Sbjct: 505 SQNGQGTPREQLLSP--------EFLVEAFRT-ASRNNILRTTDKYQELVKTLNPDQAFE 555 Query: 518 LTSVDLVRASEAHCHYVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEG 577 S + + H ++ F ++ +D ++ L L L++L+ I + G FL Sbjct: 556 ELSQQRFQCARIHTRQHLISSFYARIATAKDD-IKPHLLKLANLFALWSIEEDTGIFLRE 614 Query: 578 SIITGAQLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAK 637 +I+T + +N+ + EL +R + L DAF D + + +G YDGNVYE F Sbjct: 615 NILTPGDIDLINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVN 674 Query: 638 KSPLNKTEVHESYHKHLKPL 657 + Y LKP Sbjct: 675 QQNPATNPRPPYYESTLKPF 694 >5YS9-A nrPDB Length = 708 Score = 320 bits (820), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 203/648 (31%), Positives = 318/648 (49%), Gaps = 33/648 (5%) Query: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQ-HEDYNFLTRSQRYEVA 63 L ERA F + +T L G EN + + DP DY+ + + Q E A Sbjct: 27 LAGERAKVKFPIKDMTEFLHGGEENVTMIERLMTELERDPVLNVSGDYD-MPKEQLRETA 85 Query: 64 VKKSATMVKKMREYGISDPEEIMWFKKLYLANFVE-----PVGLNYSMFIPTLLNQGTTA 118 V + A + ++ D E+ + L V+ +G++ +F+ + GT Sbjct: 86 VARIAALSGHWKK----DTEKEALLRS-QLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKE 140 Query: 119 QQEKWMR--PSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWW 176 Q + W+R + G +A TE+GHG+++ GLETTATY T EFI+N+P + KWW Sbjct: 141 QYDYWVRKGAADVKGFYGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWW 200 Query: 177 PGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMD 236 GG ++ H A+L+ G+ YG+ FVV +R++ +H +PGI +GDIG K G + +D Sbjct: 201 IGGAAHSATHTACFARLLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAID 260 Query: 237 NGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKA 296 NG+++ N RIPR+NMLMKYA+V G +P +LTYG ++ R ++ ++ + Sbjct: 261 NGWIQFTNVRIPRQNMLMKYAKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRF 320 Query: 297 CTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRIN 356 TIA+RY+ VRRQ +PE +I+D+ Q +L PLLA YA + Y + Sbjct: 321 ITIALRYACVRRQFGTTPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTT 380 Query: 357 ESIGQGD----------LSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSG 406 + + D + +L EL A +AGLKAFTTWT I++CR ACGGHGYS +G Sbjct: 381 DLLQTIDPKDKGALGKAIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNG 440 Query: 407 IPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQ 466 Y + CT+EG+N V+ L R L++ R GK +G V YL + ++ Sbjct: 441 FGQAYADWVVQCTWEGDNNVLCLSMGRGLIQSCLGHRKGKPLGSSVGYLANKGLEQATLS 500 Query: 467 QVAVWPTMVDINSLEGLTEAYKLRAA-RLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVR 525 + V I + E + RA + VE+ L S + A+ S + Sbjct: 501 GRDLKDPKVLIEAWEKVANGAIQRATDKFVELTKGGL--------SPDQAFEELSQQRFQ 552 Query: 526 ASEAHCHYVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQL 585 ++ H +V F +++ V+ L NL L++L+ I + G FL + + Sbjct: 553 CAKIHTRKHLVTAFYERINASAKADVKPYLINLANLFTLWSIEEDSGLFLREGFLQPKDI 612 Query: 586 SQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLF 633 QV + +R DAF D + + +G YDG+VY++ F Sbjct: 613 DQVTELVNHYCKEVRDQVAGYTDAFGLSDWFINAPIGNYDGDVYKHYF 660 >1JQI-A nrPDB Length = 388 Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 52/201 (25%), Positives = 89/201 (44%), Gaps = 31/201 (15%) Query: 69 TMVKKMREYGI---SDPEEIMWFKKLYLANFVE-------------PVGLNYSMFIPTLL 112 + VKKM E G+ PEE+ YLA + + +N S+++ +L Sbjct: 45 SQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPIL 104 Query: 113 NQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTS 172 G++ Q+++W+ P IG +A +E G+G+ TTA + + ++LN Sbjct: 105 KFGSSQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAREEGDS--WVLNGTKAWI 162 Query: 173 IKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGY 232 W ++ +V A + G+ AF+VP+ P PG+T+G K G Sbjct: 163 TNSW------EASATVVFASTDRSRQNKGISAFLVPM-------PTPGLTLGKKEDKLGI 209 Query: 233 EEMDNGYLKMDNYRIPRENML 253 L ++ RIP+EN+L Sbjct: 210 RASSTANLIFEDCRIPKENLL 230 >4M9A-A nrPDB Length = 385 Score = 59.3 bits (142), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 19/161 (11%) Query: 100 VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPK 159 V ++ S+ +LN GTT Q+E+W+R + +G ++ TE G+ L T A + + Sbjct: 95 VSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTVGAFSLTEPHAGSEAHNLRTRA--ELR 152 Query: 160 TQEFILNSPT--VTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKP 217 ++ILN VT+ G + AIV A GL AFVVP Sbjct: 153 DGKWILNGSKQFVTN--------GARAGLAIVFAMTDPDEGKRGLSAFVVP-------TD 197 Query: 218 LPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQ 258 PG VG K G D + ++N IP+EN+L K + Sbjct: 198 TPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGE 238 >2VIG-A nrPDB Length = 391 Score = 55.5 bits (132), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 15/154 (9%) Query: 100 VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPK 159 + +N S+++ +L G+ Q++ W+ P IG +A +E G+G+ TTA + Sbjct: 88 MSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGD 147 Query: 160 TQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLP 219 + ++LN W ++ A+V A + + AF+VP+ P P Sbjct: 148 S--WVLNGTKAWITNAW------EASAAVVFASTDRALQNKSISAFLVPM-------PTP 192 Query: 220 GITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 G+T+G K G L ++ RIP++++L Sbjct: 193 GLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSIL 226 >4L1F-A nrPDB Length = 383 Score = 55.5 bits (132), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 79/338 (23%), Positives = 127/338 (37%), Gaps = 51/338 (15%) Query: 103 NYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQE 162 N S+ + GT Q++K++ P E +G + TE GT +TTA K + Sbjct: 90 NVSLCATPIYMFGTEEQKQKYLAPIAEGTHVGAFGLTEPSAGTDASAQQTTAVL--KGDK 147 Query: 163 FILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGIT 222 +ILN + GK ++ +V A +G+ AF++ K +PG Sbjct: 148 YILNGSKIFITN------GKEADTYVVFAMTDKSQGVHGISAFIL-------EKGMPGFR 194 Query: 223 VGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVR 282 G I K G L ++ +P+EN+L K +G K L G Sbjct: 195 FGKIEDKMGGHTSITAELIFEDCEVPKENLLGK------EGEGFKIAMETLDGGR----- 243 Query: 283 SFLVGNAAQSLS---KACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAY 339 +G AAQ+L A A++YS R Q I FQ Q+ + + Sbjct: 244 ---IGVAAQALGIAEGALAAAVKYSKEREQF-------GRSISKFQALQFMMADMATKIE 293 Query: 340 AFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGH 399 A YL + ++ + + E A+ K F + A + GG+ Sbjct: 294 AAR---------YLVYHAAMLKNEGKPYSEAAAMA---KCFASDVAMEVTTDAVQIFGGY 341 Query: 400 GYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 GY+ +EG N VM + T+R L++ Sbjct: 342 GYTVDYPAERYMRNAKITQIYEGTNQVMRIVTSRALLR 379 >1UKW-A nrPDB Length = 379 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 83/331 (25%), Positives = 137/331 (41%), Gaps = 52/331 (15%) Query: 109 PTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSP 168 P LL GT Q+E+++RP E + +A +E G+G+ L+T A + ++LN Sbjct: 96 PVLL-AGTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAIR--QGDHYVLN-- 150 Query: 169 TVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGP 228 K W G + +V A + + G+ A VV E GT PG I Sbjct: 151 ---GTKMWISN-GGEAEWVVVFATVNPELRHKGVVALVV---ERGT----PGFKAIKIHG 199 Query: 229 KFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGN 288 K G L ++ ++P EN L + +G K L T + V + VG Sbjct: 200 KMGQRASGTYELVFEDVKVPVENRLGE------EGEGFKIAMQTLNK-TRIPVAAGSVGV 252 Query: 289 AAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLL---ATAYAFHFVG 345 A ++L +A R+ ++ +++ EP I +FQ Q+KL +L TA + + Sbjct: 253 ARRALDEA----------RKYAKEREAFGEP-IANFQAIQFKLVDMLIGIETARMYTYYA 301 Query: 346 RYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSS 405 ++ + QG LP HA +A KA+ + A + GG+GY Sbjct: 302 AWLAD----------QG----LPHAHA-SAIAKAYASEIAFEAANQAIQIHGGYGYVREF 346 Query: 406 GIPNIYVTFTPACTFEGENTVMMLQTARFLM 436 + + +EG N + L AR ++ Sbjct: 347 PVEKLLRDVKLNQIYEGTNEIQRLIIARHIL 377 >5OL2-C nrPDB Length = 378 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 15/144 (10%) Query: 115 GTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIK 174 G Q++K++RP + +G + TE GT G +TTA D E+ILN + Sbjct: 101 GNEEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLD--GDEYILNGSKIFITN 158 Query: 175 WWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEE 234 G + +V+A G+ AF+V K PG + G K G Sbjct: 159 AIAGDI------YVVMAMTDKSKGNKGISAFIV-------EKGTPGFSFGVKEKKMGIRG 205 Query: 235 MDNGYLKMDNYRIPRENMLMKYAQ 258 L ++ RIP+EN+L K Q Sbjct: 206 SATSELIFEDCRIPKENLLGKEGQ 229 >3MPI-A nrPDB Length = 397 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 57/220 (25%), Positives = 93/220 (42%), Gaps = 35/220 (15%) Query: 110 TLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPT 169 T+L G+ A ++K++ + +G + TE G+ + + +TA + K ++LN Sbjct: 100 TILTYGSEALKKKYVPKLSSAEFLGGFGITEPDAGSDVMAMSSTA--EDKGDHWLLNGS- 156 Query: 170 VTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPK 229 K W + ++ I A GL AFV+ R PGI ++ K Sbjct: 157 ----KTWISNAAQ-ADVLIYYAYTDKAAGSRGLSAFVIEPRN------FPGIKTSNL-EK 204 Query: 230 FGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNA 289 G G L +DN ++P+EN+L K DG ++ +G++ R Sbjct: 205 LGSHASPTGELFLDNVKVPKENILGK----PGDGA-------RIVFGSLNHTR-LSAAAG 252 Query: 290 AQSLSKAC-TIAIRYSAVRRQSEIKQSEPEPQILDFQTQQ 328 L++AC AI+Y RRQ +P I DFQ Q Sbjct: 253 GVGLAQACLDAAIKYCNERRQF----GKP---IGDFQMNQ 285 >4N5F-A nrPDB Length = 385 Score = 49.3 bits (116), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 19/145 (13%) Query: 111 LLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPT- 169 +L GT AQ+++W+ ++IG + TE G+ L T A + +++LN Sbjct: 106 ILGFGTPAQKDRWLADMAAGRVIGAFCLTEPHAGSEANNLRTRAEL--RDGQWVLNGAKQ 163 Query: 170 -VTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGP 228 VT+ G+ + AIV A + G+ AF+VP PG VG Sbjct: 164 FVTN--------GQRAGVAIVFAMTDPEAGKRGISAFLVP-------TDTPGFIVGKPEK 208 Query: 229 KFGYEEMDNGYLKMDNYRIPRENML 253 K G D + +N IP +N+L Sbjct: 209 KMGIRASDTCPITFENCAIPEDNLL 233 >2IX5-A nrPDB Length = 436 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 74/329 (22%), Positives = 123/329 (37%), Gaps = 49/329 (14%) Query: 105 SMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFI 164 S+ + T+ G+ AQ+EK++ +L + +A TE +G+ GL TTAT + Sbjct: 141 SLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK-------V 193 Query: 165 LNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVG 224 + K W G ++ I+ A+ T + ++ F+V K PG+ Sbjct: 194 EGGWKINGQKRWIGN-STFADLLIIFARNTTTNQ---INGFIV-------KKDAPGLKAT 242 Query: 225 DIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSF 284 I K G + NG + + N +P E+ L P N + V S Sbjct: 243 KIPNKIGLRMVQNGDILLQNVFVPDEDRL--------------PGVNSFQDTSKVLAVSR 288 Query: 285 LVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFV 344 ++ A Q + + I Y R + ++ P + FQ Q KL +L A + Sbjct: 289 VM-VAWQPIGISMGI---YDMCHRYLKERKQFGAP-LAAFQLNQQKLVQMLGNVQAMFLM 343 Query: 345 GRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHS 404 G + + Y + GQ L KA+ + A R GG+G Sbjct: 344 GWRLCKLYETGQMTPGQASLG------------KAWISSKARETASLGRELLGGNGILAD 391 Query: 405 SGIPNIYVTFTPACTFEGENTVMMLQTAR 433 + + P T+EG + L T R Sbjct: 392 FLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 >4HR3-A nrPDB Length = 415 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 49/193 (25%), Positives = 72/193 (37%), Gaps = 33/193 (17%) Query: 79 ISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLN--------------QGTTAQQEKWM 124 + DPE A E +G S+F PT+ N G+ Q+E W+ Sbjct: 77 LPDPELGGGLSNSEYAPLAEQMG--RSLFAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWL 134 Query: 125 RPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 P E I + TE + AT + E ++N KWW G+G Sbjct: 135 EPLLEGDIRSAFCMTEPDVASS-DATNMAATAVVEGDEVVIN-----GRKWWSTGVGHPD 188 Query: 185 NHAIVLAQLIT-QGECYGLHAFV-VPIREIGTHKPLPGITVGDIGPKFGY--EEMDNGYL 240 I+ L Y H+ V VP+ PGITV + P G+ E +G + Sbjct: 189 CKVIIFMGLTDPNAHRYARHSMVLVPMDT-------PGITVERMLPTMGFYDEPGGHGVV 241 Query: 241 KMDNYRIPRENML 253 DN R+P + + Sbjct: 242 SFDNVRLPADAFI 254 >6ES9-A nrPDB Length = 551 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 58/216 (26%), Positives = 86/216 (39%), Gaps = 22/216 (10%) Query: 97 VEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATY 156 V +G + +L GT AQ+ KW+ +I+ T TE G+ L L T A Sbjct: 246 VGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVR 305 Query: 157 DPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHK 216 D + VT K W +T ++ + GL F+ +E GT Sbjct: 306 DGEDW-------VVTGNKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAE-KEPGTDD 357 Query: 217 ---PLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKL 273 P PG+T G+I GY M L D +RI EN+L +P + + + Sbjct: 358 DPFPTPGMTGGEI-EVLGYRGMKEYELGFDGFRIKGENLLGG----EPGRGFKQLMETFE 412 Query: 274 TYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQ 309 + R+ V AQS A I +RY+ R+Q Sbjct: 413 SARIQTAARAVGV---AQS---AAEIGMRYAVDRKQ 442 >1BUC-A nrPDB Length = 383 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 55/198 (27%), Positives = 80/198 (40%), Gaps = 31/198 (15%) Query: 115 GTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIK 174 GT AQ+EK++ P E +G + TE GT G +T AT + + LN + Sbjct: 105 GTEAQKEKFLVPLVEGTKLGAFGLTEPNAGTDASGQQTIATKNDDGT-YTLNGSKIFITN 163 Query: 175 WWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEE 234 G ++ IV A +G+ AF++ E GT PG T G K G Sbjct: 164 ------GGAADIYIVFAMTDKSKGNHGITAFIL---EDGT----PGFTYGKKEDKMGIHT 210 Query: 235 MDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLS 294 L + ++P ENML + +G K M+ + +G AAQ+L Sbjct: 211 SQTMELVFQDVKVPAENMLGE------EGKGFKI--------AMMTLDGGRIGVAAQALG 256 Query: 295 ---KACTIAIRYSAVRRQ 309 A A+ YS R Q Sbjct: 257 IAEAALADAVEYSKQRVQ 274 >2PG0-A nrPDB Length = 385 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 78/340 (22%), Positives = 133/340 (39%), Gaps = 51/340 (15%) Query: 100 VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPK 159 +GL+ + P + + GT Q++KW+ ++I A TE G G+ L + TTA D Sbjct: 91 IGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIAMTEPGAGSDLANISTTAVKDGD 150 Query: 160 TQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGE--CYGLHAFVVPIREIGTHKP 217 +I+N G ++ +V + Q + G+ VV + Sbjct: 151 Y--YIVNGQKTFITN------GIHADLIVVACKTDPQAKPPHRGISLLVV-------ERD 195 Query: 218 LPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGT 277 PG T G K G D L + ++P N+L + +G L KL Sbjct: 196 TPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGE------EGKGFYYLMEKLQQER 249 Query: 278 MVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLAT 337 +V V AAQ+ ++ ++ +Q +++ ++ +FQT Q++L +AT Sbjct: 250 LV------VAIAAQTAAEVMF------SLTKQYVKQRTAFGKRVSEFQTVQFRLAE-MAT 296 Query: 338 AYAFH--FVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMA 395 A FV R ++E G+ ++E+ + K + T A E Sbjct: 297 EIALGRTFVDRVIEE------HMAGKQIVTEV-------SMAKWWITEMAKRVAAEAMQL 343 Query: 396 CGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 GG+GY I Y + + G N +M AR L Sbjct: 344 HGGYGYMEEYEIARRYRDIPVSAIYAGTNEMMKTIIARQL 383 >3B96-A nrPDB Length = 587 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 88/429 (20%), Positives = 160/429 (37%), Gaps = 69/429 (16%) Query: 49 EDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEI--MWFKKLYLANFVEPVGLN--- 103 E+ N ++ E+ + + +K++ +G+ P E+ + A VE VG++ Sbjct: 46 EEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLG 105 Query: 104 --------YSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTAT 155 S+ +L GT AQ+EK++ + + + TE G+ + T+A Sbjct: 106 VGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAV 165 Query: 156 YDPKTQEFILNSPTVTSIKWW--PGGLGKTSNHAIVLAQLITQGECYG-----LHAFVVP 208 P + + LN K W GGL ++ V A+ G + AFVV Sbjct: 166 PSPCGKYYTLNGS-----KLWISNGGL---ADIFTVFAKTPVTDPATGAVKEKITAFVV- 216 Query: 209 IREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKP 268 + GIT G K G + + + D R+P EN+L +V Sbjct: 217 ------ERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL---GEVGSGFKVAMH 267 Query: 269 LSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQ 328 + N +G + + G A+++ A +++ +I +F Q Sbjct: 268 ILNNGRFGMAAALAGTMRGIIAKAVDHATN---------------RTQFGEKIHNFGLIQ 312 Query: 329 YKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAG 388 KL ++ Y + YM ++ ++ QG + A K F + A Sbjct: 313 EKLARMVMLQYVTESMA-YM------VSANMDQG----ATDFQIEAAISKIFGSEAAWKV 361 Query: 389 IEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLV 448 +EC GG G+ G+ + FEG N ++ R + + + GK + Sbjct: 362 TDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDIL-----RLFVALQGCMDKGKEL 416 Query: 449 GGMVSYLND 457 G+ S L + Sbjct: 417 SGLGSALKN 425 >3MDE-A nrPDB Length = 385 Score = 42.4 bits (98), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 13/146 (8%) Query: 108 IPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNS 167 +P ++ G QQ+K++ E ++ Y TE G G+ + G++T A + K E+I+N Sbjct: 96 VPLIIG-GNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIING 152 Query: 168 PTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIG 227 K W GK +N +LA+ + AF I E T PG+ +G Sbjct: 153 Q-----KMWITNGGK-ANWYFLLARSDPDPKAPASKAFTGFIVEADT----PGVQIGRKE 202 Query: 228 PKFGYEEMDNGYLKMDNYRIPRENML 253 G D + ++ R+P+EN+L Sbjct: 203 INMGQRCSDTRGIVFEDVRVPKENVL 228 >4U83-A nrPDB Length = 382 Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 42/154 (27%), Positives = 60/154 (38%), Gaps = 15/154 (9%) Query: 100 VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPK 159 V ++ S+ +L GT Q+ +++ + IG +A TE G+ L+T A D Sbjct: 92 VSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFALTEPQAGSDASALKTRARLDGD 151 Query: 160 TQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLP 219 + +TS GK N IV A G+ AF+VP P Sbjct: 152 HYVIDGSKQFITS--------GKNGNVVIVFAVTDPAAGKKGISAFIVPT-------DTP 196 Query: 220 GITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 G V + K G D L N R+P EN L Sbjct: 197 GYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRL 230 >6FAH-C nrPDB Length = 379 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 77/333 (23%), Positives = 130/333 (39%), Gaps = 57/333 (17%) Query: 111 LLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTV 170 LL GT Q EK+++P + +A TE G G+ G+ TTA ++ L + Sbjct: 97 LLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAGGMSTTAV---DMGDYYLLNGRK 153 Query: 171 TSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKF 230 T I P + A++ A+ G+ AF+V ++ G+++G K Sbjct: 154 TFITMAP-----LCDDAVIYAKTDMSKGTRGISAFIVDLKS-------EGVSMGKNEHKM 201 Query: 231 GYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAA 290 G + M++ ++P+EN L G K SN + T+ R +G A+ Sbjct: 202 GLIGCATSDIIMEDVKVPKENRL---------GEVNKGFSNAMK--TLDVGR---LGVAS 247 Query: 291 QSLS---KACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRY 347 QS+ A AI+Y+ R+Q +I DFQ A A+ + Sbjct: 248 QSIGVAQGALDEAIKYAKERKQFG-------KRIADFQ----------AIAFMIADMATK 290 Query: 348 MKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMAC---GGHGYSHS 404 ++ L + + D + A A K + + N E C A GG+GY Sbjct: 291 LEAAKLLVYNAASLMDNKKNATKEASMA--KFYASEICN---EICAKAVQIHGGYGYIKE 345 Query: 405 SGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 + +Y +EG + V + + L+K Sbjct: 346 YKVERMYRDCRVFTIYEGTSQVQQMVISGMLLK 378 >2Z1Q-A nrPDB Length = 577 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 72/342 (21%), Positives = 134/342 (39%), Gaps = 43/342 (12%) Query: 101 GLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKT 160 G + S+ L+ GT Q+ K++ + I Y TE G G+ +T AT Sbjct: 111 GAHTSIGTLPLVYFGTEEQKRKYLPKLASGEWIAAYCLTEPGSGSDALAAKTRATLSEDG 170 Query: 161 QEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPG 220 + +ILN +K W G ++ V A++ GE + AF+V + PG Sbjct: 171 KHYILN-----GVKQWISNAG-FAHLFTVFAKV--DGEHF--TAFLV-------ERDTPG 213 Query: 221 ITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVF 280 ++ G K G + + +++ ++P EN+L + + +K+ + + Sbjct: 214 LSFGPEEKKMGIKASSTRQVILEDVKVPVENVLGEIGK-----------GHKIAFNVLNV 262 Query: 281 VRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYA 340 R L A +A ++ +Y+ R ++ P I F Q KL + + YA Sbjct: 263 GRYKLGAGAVGGAKRALELSAQYATQR----VQFGRP---IGRFGLIQQKLGEMASRIYA 315 Query: 341 FHFVGRYMKETYLRINESI-----GQGDLSELPELHALTAGLKAFTTWTANAGIEECRMA 395 + T I+E++ + ++ + E + +K + + ++E Sbjct: 316 AESA---VYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQI 372 Query: 396 CGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 GG+GYS I Y FEG N + L L++ Sbjct: 373 HGGYGYSQEYPIERAYRDARINRIFEGTNEINRLLIPGMLLR 414 >2A1T-A nrPDB Length = 421 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 48/194 (24%), Positives = 80/194 (41%), Gaps = 23/194 (11%) Query: 115 GTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIK 174 G Q++K++ E ++ Y TE G G+ + G++T A + K E+I+N K Sbjct: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIINGQ-----K 189 Query: 175 WWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEE 234 W GK +N +LA+ + AF I E T PGI +G G Sbjct: 190 MWITNGGK-ANWYFLLARSDPDPKAPANKAFTGFIVEADT----PGIQIGRKELNMGQRC 244 Query: 235 MDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLS 294 D + ++ ++P+EN+L+ DG K+ G R + A Sbjct: 245 SDTRGIVFEDVKVPKENVLIG------DGA-----GFKVAMGAFDKTRPVVAAGAVGLAQ 293 Query: 295 KACTIAIRYSAVRR 308 +A A +Y+ R+ Sbjct: 294 RALDEATKYALERK 307 >3R7K-A nrPDB Length = 403 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 20/154 (12%) Query: 102 LNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQ 161 + + +P + G+ A E+++RP+ ++IG+ TE G G+ + L T A + T Sbjct: 114 FTHGIALPHIAANGSDALIERYVRPTLAGKMIGSLGVTEPGAGSDVANLRTRAVREGDT- 172 Query: 162 EFILNSPT--VTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLP 219 +++N +TS G ++ V + T G YG + +V K P Sbjct: 173 -YVVNGAKTFITS--------GVRAD--FVTTAVRTGGPGYGGVSLLV------IDKNSP 215 Query: 220 GITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 G V K G+ D L + R+P +N++ Sbjct: 216 GFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLV 249 >4KTO-A nrPDB Length = 410 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 59/243 (24%), Positives = 95/243 (39%), Gaps = 39/243 (16%) Query: 100 VGLNYSMFIPTLLNQ----GTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTAT 155 VGL+Y +NQ G AQ+ +++ + +G A +E G G+ + ++ A Sbjct: 111 VGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEHVGALAMSEPGAGSDVVSMKLKA- 169 Query: 156 YDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTH 215 D + ++LN K W G ++ +V A+ G+ AF+V Sbjct: 170 -DKRGDRYVLNGS-----KMWITN-GPDADVLVVYAKTDPAAGPRGITAFLV-------E 215 Query: 216 KPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTY 275 K PG + G K G + L + +P EN+L G VK L + L Y Sbjct: 216 KAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGV------GEGVKVLMSGLDY 269 Query: 276 GTMVFVRSFLVGNAAQSLSKAC-TIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPL 334 +V L + AC + + Y R+Q +P I +FQ Q KL + Sbjct: 270 ERVVLSAGPL------GIMAACLDVVVPYLHERKQF----GQP---IGEFQLMQGKLADM 316 Query: 335 LAT 337 T Sbjct: 317 YVT 319 >3OWA-A nrPDB Length = 597 Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust. Identities = 74/328 (22%), Positives = 128/328 (39%), Gaps = 54/328 (16%) Query: 115 GTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIK 174 G Q++K++ + + YA TE G G+ G +TTA + + ++LN K Sbjct: 130 GNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGE-----K 184 Query: 175 WWPGGLGKTSNHA-----IVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPK 229 W +N A IV A++ GE + AF+V K G++ K Sbjct: 185 QW------ITNSAFADVFIVYAKI--DGEHF--SAFIV-------EKDYAGVSTSPEEKK 227 Query: 230 FGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNA 289 G + L +++ +P+EN+L + + + + + + R L Sbjct: 228 MGIKCSSTRTLILEDALVPKENLLGEIGK-----------GHIIAFNILNIGRYKLGVGT 276 Query: 290 AQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYA-----FHFV 344 S +A I+ +Y+ R+Q KQ I F Q KL + A YA + V Sbjct: 277 VGSAKRAVEISAQYANQRQQ--FKQP-----IARFPLIQEKLANMAAKTYAAESSVYRTV 329 Query: 345 GRYMKETYLRINESI--GQGDLSELPELHALTAGL-KAFTTWTANAGIEECRMACGGHGY 401 G + E + G+ + + E +A+ L K F + + ++E GG+G+ Sbjct: 330 GLFESRMSTLSEEEVKDGKAVAASIAE-YAIECSLNKVFGSEVLDYTVDEGVQIHGGYGF 388 Query: 402 SHSSGIPNIYVTFTPACTFEGENTVMML 429 I +Y FEG N + L Sbjct: 389 MAEYEIERMYRDSRINRIFEGTNEINRL 416 >3SWO-A nrPDB Length = 399 Score = 37.7 bits (86), Expect = 0.016, Method: Compositional matrix adjust. Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 20/160 (12%) Query: 94 ANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETT 153 + F V + S+ + ++ G+ Q+ +W+ IG + TE G++ G+ T Sbjct: 101 SGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTR 160 Query: 154 ATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIG 213 A D ++ILN K W G ++ A V AQ G+ F+VP Sbjct: 161 ARRD--GSDWILNG-----TKMWITN-GNLADVATVWAQTDD-----GIRGFLVPT---- 203 Query: 214 THKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 PG T +I K L +DN R+P L Sbjct: 204 ---DTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQL 240 >3SF6-A nrPDB Length = 403 Score = 37.7 bits (86), Expect = 0.017, Method: Compositional matrix adjust. Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 20/134 (14%) Query: 115 GTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIK 174 G+ Q+++W+ IG + TE HG+ G+ T AT ++IL T K Sbjct: 127 GSDEQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATR--SGDDWIL-----TGTK 179 Query: 175 WWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEE 234 W G ++ A+V A+ G+ FVVP PG T I K Sbjct: 180 MWITN-GSVADVAVVWARTDE-----GIRGFVVP-------TDTPGFTANTIKSKMSLRA 226 Query: 235 MDNGYLKMDNYRIP 248 L +D R+P Sbjct: 227 SVTSELVLDGVRLP 240 >5LNX-A nrPDB Length = 379 Score = 37.4 bits (85), Expect = 0.022, Method: Compositional matrix adjust. Identities = 70/326 (21%), Positives = 122/326 (37%), Gaps = 45/326 (13%) Query: 111 LLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTV 170 +L G Q+ K++ +G +A TE G+ L TTA K +++LN + Sbjct: 96 ILYFGNEEQKMKYIPNLASGDHLGAFALTEPHSGSDAGSLRTTAI--KKNGKYLLNGSKI 153 Query: 171 TSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKF 230 G ++ I A +G+ AF+V K PG TVG K Sbjct: 154 FITN------GGAADIYITFALTAPDQGRHGISAFIV-------EKNTPGFTVGKKERKL 200 Query: 231 GYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAA 290 G + L DN +P N+L K + DG ++ M + +G AA Sbjct: 201 GLYGSNTTELIFDNAEVPEANLLGK----EGDGFHI----------AMANLNVGRIGIAA 246 Query: 291 QSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKE 350 Q+L A A+ ++ + ++ P I Q +KL + A A + + + Sbjct: 247 QALGIA-EAALEHAVDYAKQRVQFGRP---IAANQGISFKLADMATRAEAARHLVYHAAD 302 Query: 351 TYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNI 410 + N + G + + + A A +KA + GG+GY + + Sbjct: 303 LH---NRGLNCGKEASMAKQFASDAAVKAAL---------DAVQIYGGYGYMKDYPVERL 350 Query: 411 YVTFTPACTFEGENTVMMLQTARFLM 436 +EG N + L +++L+ Sbjct: 351 LRDAKVTQIYEGTNEIQRLIISKYLL 376 >1SIR-A nrPDB Length = 394 Score = 37.0 bits (84), Expect = 0.025, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 17/139 (12%) Query: 115 GTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIK 174 G+ Q++K++ + +++G + TE G+ +ET A Y+ + + LN T T I Sbjct: 112 GSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNG-TKTWIT 170 Query: 175 WWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEE 234 P ++ +V A+ + C IR K + G++ I KF Sbjct: 171 NSP-----MADLFVVWAR--CEDGC---------IRGFLLEKGMRGLSAPRIQGKFSLRA 214 Query: 235 MDNGYLKMDNYRIPRENML 253 G + MD +P EN+L Sbjct: 215 SATGMIIMDGVEVPEENVL 233 >2DVL-A nrPDB Length = 372 Score = 36.2 bits (82), Expect = 0.042, Method: Compositional matrix adjust. Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 26/146 (17%) Query: 111 LLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTV 170 LL G+ AQ+ +++ P + IG + TE G+ + L A F+LN Sbjct: 96 LLRFGSEAQKRRYLVPLARGEWIGAFCLTEPQAGSDAKSLRAEARRVKGG--FVLNG--- 150 Query: 171 TSIKWWPGGLGKTSNHA---IVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIG 227 +K W ++ HA +V+A+ G+ AF+V E GT PG++ G Sbjct: 151 --VKSWI----TSAGHAHLYVVMARTEK-----GISAFLV---EKGT----PGLSFGRPE 192 Query: 228 PKFGYEEMDNGYLKMDNYRIPRENML 253 K G ++++ +P EN+L Sbjct: 193 EKMGLHAAHTAEVRLEEVFVPEENLL 218 >2JIF-A nrPDB Length = 404 Score = 36.2 bits (82), Expect = 0.045, Method: Compositional matrix adjust. Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 21/150 (14%) Query: 107 FIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILN 166 I TL+ + T +Q+ P + +G++ +E G G+ L+T A D + ++LN Sbjct: 117 LINTLIRKHGTEEQKATYLPQLTTEKVGSFCLSEAGAGSDSFALKTRA--DKEGDYYVLN 174 Query: 167 SPTVTSIKWWPGGLGKTSNHA---IVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITV 223 K W ++ HA +V+A + G+ +F+V + PG+ + Sbjct: 175 GS-----KMWI----SSAEHAGLFLVMANVDPTIGYKGITSFLV-------DRDTPGLHI 218 Query: 224 GDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 G K G L +N ++P N+L Sbjct: 219 GKPENKLGLRASSTCPLTFENVKVPEANIL 248 >3P4T-A nrPDB Length = 403 Score = 35.8 bits (81), Expect = 0.057, Method: Compositional matrix adjust. Identities = 39/162 (24%), Positives = 67/162 (41%), Gaps = 25/162 (15%) Query: 99 PVGLNYSMF-----IPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETT 153 P G+ S+F +P ++ G + ++RP+ + IG A TE G G+ + L T Sbjct: 103 PGGVYASLFTCGIAVPHMIASGDQRLIDTYVRPTLRGEKIGALAITEPGGGSDVGHLRTR 162 Query: 154 ATYDPKTQEFILNSPT--VTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIRE 211 A D +++N +TS G +++ + A+ T G G + +V Sbjct: 163 ADLD--GDHYVINGAKTYITS--------GVRADYVVTAAR--TGGPGAGGVSLIV---- 206 Query: 212 IGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 K PG V K G+ D L + R+P N++ Sbjct: 207 --VDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLV 246 >3PFD-A nrPDB Length = 393 Score = 35.4 bits (80), Expect = 0.070, Method: Compositional matrix adjust. Identities = 69/307 (22%), Positives = 115/307 (37%), Gaps = 44/307 (14%) Query: 131 QIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVL 190 + + +YA +E G+ + T A D ++ILN K W GK++ + ++ Sbjct: 131 EAMASYALSEREAGSDAASMRTRAVAD--GDDWILNGS-----KCWITNGGKSTWYTVMA 183 Query: 191 AQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRE 250 +G G+ AF+V HK G TVG K G + L +N RIP + Sbjct: 184 VTDPDKG-ANGISAFMV-------HKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGD 235 Query: 251 NMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQS 310 ++ +P + K T+ R + A A AI Y+ R+Q Sbjct: 236 RIIG-----EPGTGF------KTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQF 284 Query: 311 EIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPEL 370 P + D Q Q+ L + A R M + E G+GDL Sbjct: 285 ----GRP---VSDNQGVQFMLADMAMKIEA----ARLMVYSAAARAER-GEGDLG----- 327 Query: 371 HALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQ 430 ++A K F + A + GG+GY+ + + +EG N + + Sbjct: 328 -FISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEGTNQIQRVV 386 Query: 431 TARFLMK 437 +R L++ Sbjct: 387 MSRALLR 393 >4IV6-A nrPDB Length = 388 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 14/143 (9%) Query: 111 LLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTV 170 LL GT Q++K++ ++ T A TE G G+ L+ + T A D ++++N Sbjct: 99 LLLFGTEEQKQKYLPRMATGELRATMALTEPGGGSDLQAMRTVARRD--GDDYVINGS-- 154 Query: 171 TSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKF 230 K W + +V T + H V I + +PG V PK Sbjct: 155 ---KTW---ISNARRSDLVALMCKTDPDAQPAHKGV----SILLVEKVPGFDVSRDLPKL 204 Query: 231 GYEEMDNGYLKMDNYRIPRENML 253 GY+ +++ L + R+P ++L Sbjct: 205 GYKGVESCELNFTDARVPVSSLL 227 >1V2Y-A nrPDB Length = 105 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 27/45 (60%) Query: 47 QHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKL 91 QH ++++ R+ A +K KK+R+YGI + +E+ + KKL Sbjct: 52 QHISWSYVWRTYHLTSAGEKLTEDRKKLRDYGIRNRDEVSFIKKL 96 >4LD0-A nrPDB Length = 169 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 29/51 (56%) Query: 584 QLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFE 634 ++ +++AR+LE+L RP AVA+ + F ++ L +G G V FE Sbjct: 50 RVGRIHARVLEVLHRFRPEAVAVQEQFFYRQNELAYKVGWALGAVLVAAFE 100 >3GNC-A nrPDB Length = 399 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 36/155 (23%), Positives = 57/155 (36%), Gaps = 28/155 (18%) Query: 105 SMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDP------ 158 S+ + + G+ AQ+EK++ + IG + TE HG+ + T A P Sbjct: 109 SLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVPGGYSLS 168 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 ++ +I NSP W A+L G IR K Sbjct: 169 GSKMWITNSPIADVFVVW--------------AKLDEDGRD--------EIRGFILEKGC 206 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 G++ I K G G + +D +P EN+L Sbjct: 207 KGLSAPAIHGKVGLRASITGEIVLDEAFVPEENIL 241 >3NF4-A nrPDB Length = 387 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 36/149 (24%), Positives = 58/149 (38%), Gaps = 19/149 (12%) Query: 111 LLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTV 170 LL GT Q+++W+ + IG Y+ +E G+ L AT P +++N Sbjct: 108 LLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAAT--PTDGGYVINGS-- 163 Query: 171 TSIKWWPGGLGKTSNHAIVLAQLITQGE-CYGLHAFVVPIREIGTHKPLPGITVGDIGPK 229 K W GK + + GE G+ F+VP + PG++ G K Sbjct: 164 ---KSWITHGGKADFYTL----FARTGEGSRGVSCFLVPADQ-------PGLSFGKPEEK 209 Query: 230 FGYEEMDNGYLKMDNYRIPRENMLMKYAQ 258 G + DN RI + + + Q Sbjct: 210 MGLHAVPTTSAFYDNARIDADRRIGEEGQ 238 >3U33-A nrPDB Length = 541 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 5/82 (6%) Query: 389 IEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK---IYDQVRSG 445 + E GG GY S +P +Y +EG +M L R L K +YD + Sbjct: 393 VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLSEA 452 Query: 446 KL-VGGMVSYLNDLPSQRIQPQ 466 + V G Y D +R+Q Q Sbjct: 453 FVEVKGQDRYF-DRAVRRLQQQ 473 >1SC7-A nrPDB Length = 592 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 8/75 (10%) Query: 411 YVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAV 470 Y+ P+ +GE +TAR L K D++R+ Y D S+ ++ +Q AV Sbjct: 253 YIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRN--------QYREDWKSKEMKVRQRAV 304 Query: 471 WPTMVDINSLEGLTE 485 +D +L E Sbjct: 305 ALYFIDKLALRAGNE 319 >3JXA-A nrPDB Length = 383 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Query: 16 PELITHILDGSPENTRRRREIENLILNDPDFQHED---YNFLTRSQRYEVAVKKSATM-- 70 P ++ DG P + RR N IL P+FQ ED Y + + R + K T Sbjct: 234 PTILWRRADGKPIARKARRHKSNGILEIPNFQQEDAGSYECVAENSRGKNVAKGQLTFYA 293 Query: 71 ----VKKMREYGISDPEEIMW 87 V+ + + ++ E + W Sbjct: 294 QPNWVQIINDIHVAMEESVFW 314 >1FOK-A nrPDB Length = 576 Score = 29.3 bits (64), Expect = 5.2, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 10/108 (9%) Query: 446 KLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIAAKNLQTH 505 +++GG + L + Q ++ + PT+ ++ E ++ A+K+ L + T Sbjct: 225 RMIGGWLDKLGLVK----QGKKEFIIPTLGKPDNKEFISHAFKITGEGLKVLRRAKGSTK 280 Query: 506 VSHRKSKEVAW-----NLTSVDLVRASEAHCHYVVVKVFSDKLPKIQD 548 + R K V W NLT + VR A +++K S K+ +IQD Sbjct: 281 FT-RVPKRVYWEMLATNLTDKEYVRTRRALILEILIKAGSLKIEQIQD 327 >5EZ3-A nrPDB Length = 573 Score = 28.9 bits (63), Expect = 7.8, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 3/83 (3%) Query: 363 DLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEG 422 D +E ++T +K + A A + E GG+GY + Y +EG Sbjct: 397 DRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEG 456 Query: 423 ENTVMMLQTARFLMK---IYDQV 442 VM L AR L + ++D V Sbjct: 457 SGNVMALDVARVLSRAPALFDGV 479 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1IS2-A nrPDB 931 0.0 1W07-A nrPDB 792 0.0 2FON-A nrPDB 790 0.0 5K3G-A nrPDB 779 0.0 5K3J-A nrPDB 768 0.0 5YS9-A nrPDB 744 0.0 5Y9D-A nrPDB 725 0.0 3B96-A nrPDB 344 7e-95 2Z1Q-A nrPDB 297 1e-80 4L1F-A nrPDB 296 3e-80 1JQI-A nrPDB 286 2e-77 4N5F-A nrPDB 286 2e-77 1UKW-A nrPDB 282 3e-76 5OL2-C nrPDB 277 1e-74 2PG0-A nrPDB 275 3e-74 2VIG-A nrPDB 275 3e-74 6FAH-C nrPDB 274 9e-74 4U83-A nrPDB 269 2e-72 4M9A-A nrPDB 267 1e-71 1BUC-A nrPDB 266 3e-71 2IX5-A nrPDB 254 7e-68 3MDE-A nrPDB 230 2e-60 6ES9-A nrPDB 227 9e-60 3MPI-A nrPDB 217 1e-56 4HR3-A nrPDB 200 2e-51 Sequences not found previously or not previously below threshold: 3OWA-A nrPDB 269 3e-72 5LNX-A nrPDB 265 6e-71 3PFD-A nrPDB 245 6e-65 2A1T-A nrPDB 237 1e-62 4KTO-A nrPDB 223 1e-58 4O5M-A nrPDB 221 7e-58 3NF4-A nrPDB 219 4e-57 2DVL-A nrPDB 213 2e-55 1IVH-A nrPDB 210 2e-54 4IV6-A nrPDB 209 3e-54 2JIF-A nrPDB 208 7e-54 1RX0-A nrPDB 205 4e-53 2CX9-A nrPDB 204 9e-53 4IRN-A nrPDB 201 7e-52 3GNC-A nrPDB 189 3e-48 3SF6-A nrPDB 189 3e-48 5IDU-A nrPDB 186 2e-47 5JSC-A nrPDB 183 3e-46 3R7K-A nrPDB 179 3e-45 3SWO-A nrPDB 173 2e-43 1SIR-A nrPDB 173 2e-43 4W9U-A nrPDB 173 3e-43 2EBA-A nrPDB 165 4e-41 3P4T-A nrPDB 164 1e-40 5ZW7-A nrPDB 163 2e-40 6CY8-B nrPDB 158 7e-39 2WBI-A nrPDB 139 3e-33 5AHS-A nrPDB 138 6e-33 4X28-A nrPDB 126 3e-29 5EZ3-A nrPDB 104 2e-22 1R2J-A nrPDB 103 3e-22 4RM7-A nrPDB 98 1e-20 4Y9J-A nrPDB 95 7e-20 3U33-A nrPDB 93 4e-19 4ZYJ-A nrPDB 81 2e-15 3MXL-A nrPDB 80 2e-15 5GJ7-A nrPDB 79 6e-15 3M9V-A nrPDB 78 1e-14 3MKH-A nrPDB 77 2e-14 5XDD-A nrPDB 75 1e-13 2C12-A nrPDB 72 1e-12 4XVX-A nrPDB 66 6e-11 4JEK-A nrPDB 65 1e-10 4X28-D nrPDB 61 2e-09 5LVW-A nrPDB 46 5e-05 3AFF-A nrPDB 41 0.002 2RFQ-A nrPDB 35 0.12 2GQD-A nrPDB 30 2.9 6CU3-A nrPDB 30 3.0 6CG0-N nrPDB 30 3.3 6CIM-N nrPDB 30 4.0 2GZK-A nrPDB 29 4.8 >1IS2-A nrPDB Length = 661 Score = 931 bits (2405), Expect = 0.0, Method: Composition-based stats. Identities = 634/661 (95%), Positives = 642/661 (97%) Query: 1 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRY 60 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRY Sbjct: 1 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRY 60 Query: 61 EVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQ 120 EVAVKKSATMVKKMREYGISDPEEIMWFK EP+ L+ MF+PTLL+Q T QQ Sbjct: 61 EVAVKKSATMVKKMREYGISDPEEIMWFKNSVHRGHPEPLDLHLGMFLPTLLHQATAEQQ 120 Query: 121 EKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGL 180 E++ P+ L+I GTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGL Sbjct: 121 ERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGL 180 Query: 181 GKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYL 240 GKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYL Sbjct: 181 GKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYL 240 Query: 241 KMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 KMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA Sbjct: 241 KMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 Query: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG Sbjct: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 Query: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF Sbjct: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 Query: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSL 480 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSL Sbjct: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSL 480 Query: 481 EGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFS 540 EGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFS Sbjct: 481 EGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVKVFS 540 Query: 541 DKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIR 600 DKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIR Sbjct: 541 DKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLTLIR 600 Query: 601 PNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPLQSK 660 PNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPLQSK Sbjct: 601 PNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPLQSK 660 Query: 661 L 661 L Sbjct: 661 L 661 >1W07-A nrPDB Length = 659 Score = 792 bits (2045), Expect = 0.0, Method: Composition-based stats. Identities = 294/664 (44%), Positives = 411/664 (61%), Gaps = 21/664 (3%) Query: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 L ER A F+ E + + GS I L+ +DP F+ + L+R + ++ + Sbjct: 7 LADERNKAEFDVEDMKIVWAGSRHAFEVSDRIARLVASDPVFEKSNRARLSRKELFKSTL 66 Query: 65 KKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWM 124 +K A K++ E +++ E + +V+ L++ MF+P + QGT QQ+KW+ Sbjct: 67 RKCAHAFKRIIELRLNEEEAGRLRHFIDQPAYVD---LHWGMFVPAIKGQGTEEQQKKWL 123 Query: 125 RPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 + ++QIIG YAQTE+GHG++++GLETTAT DPKT EF++++PT T+ KWWPGGLGK S Sbjct: 124 SLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDEFVIHTPTQTASKWWPGGLGKVS 183 Query: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLK 241 HA+V A+LIT G+ YG+H F+V +R + H PLP ITVGDIG K G Y MDNG+L Sbjct: 184 THAVVYARLITNGKDYGIHGFIVQLRSLEDHSPLPNITVGDIGTKMGNGAYNSMDNGFLM 243 Query: 242 MDNYRIPRENMLMKYAQVKPDGTYV-KPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 D+ RIPR+ MLM+ ++V +G YV + +L YGTMV+VR +V +A+ +LS+A IA Sbjct: 244 FDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQTIVADASNALSRAVCIA 303 Query: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 RYSAVRRQ E Q++D++TQQ +LFPLLA+AYAF FVG ++K Y + E + Sbjct: 304 TRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTERLA 363 Query: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 D + LPE HA TAGLK+ TT GIEECR CGGHGY SG+P ++ + PACT+ Sbjct: 364 ASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGYLWCSGLPELFAVYVPACTY 423 Query: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLN---DLPSQRIQPQQVAVWPTMVDI 477 EG+N V+ LQ ARFLMK Q+ SGK+ G +Y+ L R Q+ W Sbjct: 424 EGDNVVLQLQVARFLMKTVAQLGSGKVPVGTTAYMGRAAHLLQCRSGVQKAEDW------ 477 Query: 478 NSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVK 537 + + + EA++ RA R+ AKNL S +++E + DLV A+ AHC +VV Sbjct: 478 LNPDVVLEAFEARALRMAVTCAKNL----SKFENQEQGFQELLADLVEAAIAHCQLIVVS 533 Query: 538 VFSDKLPK-IQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELL 596 F KL + I K V+ L NLC +Y+LY + + GDFL + IT Q S N ++ L Sbjct: 534 KFIAKLEQDIGGKGVKKQLNNLCYIYALYLLHKHLGDFLSTNCITPKQASLANDQLRSLY 593 Query: 597 TLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKP 656 T +RPNAVALVDAF++ D L SVLGRYDGNVY LFE A K PLN + V + Y ++L+P Sbjct: 594 TQVRPNAVALVDAFNYTDHYLNSVLGRYDGNVYPKLFEEALKDPLNDSVVPDGYQEYLRP 653 Query: 657 LQSK 660 + + Sbjct: 654 VLQQ 657 >2FON-A nrPDB Length = 683 Score = 790 bits (2039), Expect = 0.0, Method: Composition-based stats. Identities = 297/664 (44%), Positives = 421/664 (63%), Gaps = 21/664 (3%) Query: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 L ER A F+ + + + GS + I L+ +DP F E L R + ++ + Sbjct: 26 LADERKKAGFDVDEMKIVWAGSRHDFELTDRISKLVASDPGFSKEGRTMLPRKELFKNTL 85 Query: 65 KKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWM 124 +K+A K++ E +S E M + + F + L++ MFIP + QGT QQEKW+ Sbjct: 86 RKAAYAWKRIIELRLSQEEATMLRRYVDEPAFTD---LHWGMFIPAIKGQGTDKQQEKWL 142 Query: 125 RPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 + ++QIIG YAQTE+GHG++++GLETTAT+DP+T EF+++SPT+TS KWWPGGLGK S Sbjct: 143 PLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDEFVIHSPTLTSSKWWPGGLGKVS 202 Query: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG---YEEMDNGYLK 241 HA+V A+LIT G+ YG++ F+V +R + HKPLPG+TVGDIG KFG Y MDNG L Sbjct: 203 THAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGVTVGDIGMKFGNGAYNSMDNGVLS 262 Query: 242 MDNYRIPRENMLMKYAQVKPDGTYVK-PLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIA 300 D+ RIPR+ MLM+ +QV +G YV+ + +L YGTMV+VR +V +A+ ++S+A IA Sbjct: 263 FDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGTMVYVRQSIVADASLAMSRAVCIA 322 Query: 301 IRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIG 360 RYSAVRRQ + E Q++D++TQQ +LFPLLA+AYAF FVG ++K Y + + + Sbjct: 323 TRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFPLLASAYAFRFVGEWLKWLYTDVTQRLA 382 Query: 361 QGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTF 420 D S LPE HA TAGLK+ TT GIEECR CGGHGY SSG+P ++ + PACT+ Sbjct: 383 ANDFSTLPEAHACTAGLKSLTTSATADGIEECRKLCGGHGYLCSSGLPELFAVYVPACTY 442 Query: 421 EGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLN---DLPSQRIQPQQVAVWPTMVDI 477 EG+N V+ LQ ARFLMK Q+ +GK G VSY+ L R +Q W Sbjct: 443 EGDNVVLQLQVARFLMKTISQLGTGKKPVGTVSYMGRIEHLMQCRSDVKQAEDW------ 496 Query: 478 NSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVK 537 + EA++ R+AR+ AKNL S +++E + + DLV A+ AHC +VV Sbjct: 497 LKPSAVLEAFEARSARMSVACAKNL----SKFENQEEGFAELAADLVEAAVAHCQLIVVS 552 Query: 538 VFSDKLPK-IQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELL 596 + +KL + I K V+ L LC +YSL+ + + GDFL IT Q S N ++ L Sbjct: 553 KYIEKLQQNIPGKGVKQQLEVLCGIYSLFILHKHQGDFLGTGYITSKQGSLANDQLRALY 612 Query: 597 TLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKP 656 + +RPNAV+LVDAF++ D LGS+LGRYDGNVY L+E A K PLNK+++ + +H++++P Sbjct: 613 SQLRPNAVSLVDAFNYTDHYLGSILGRYDGNVYPKLYEAAWKDPLNKSDIADGFHEYIRP 672 Query: 657 LQSK 660 L + Sbjct: 673 LLKQ 676 >5K3G-A nrPDB Length = 684 Score = 779 bits (2011), Expect = 0.0, Method: Composition-based stats. Identities = 289/666 (43%), Positives = 414/666 (62%), Gaps = 17/666 (2%) Query: 2 NPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHE-DYNFLTRSQRY 60 NPDL ER +ATF+ + + G RRRREI + P+ ++TR ++ Sbjct: 13 NPDLTAERLTATFDTHAMAAQIYGGEMRARRRREITAKLAEIPELHDSMPLPYMTREEKI 72 Query: 61 EVAVKKSATMVKKMREYGIS-DPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQ 119 + +K + ++M E D E+ L P+ L+ MFIP L Q + Q Sbjct: 73 MESARKLTVLTQRMSEIIDPTDAGELYHLNNEVLGIEGNPMALHGVMFIPALNAQASDEQ 132 Query: 120 QEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGG 179 Q KW+ + +IIGTYAQTEMGHGT+L+ LETTATYD TQEF+L++P +T++KWWPG Sbjct: 133 QAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIGTQEFVLHTPKITALKWWPGN 192 Query: 180 LGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGY 239 LGK+SN+A+V+A + +G+ +G H F+VP+R+ THKPLPGIT+GDIGPK Y +DNG+ Sbjct: 193 LGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHKPLPGITIGDIGPKMAYNIVDNGF 252 Query: 240 LKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTI 299 L +NYRIPR N+LM++ +V+ DGTY+KP K+ Y MV VRS+++ A LS A I Sbjct: 253 LGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKINYSAMVHVRSYMLTGQAIMLSYALNI 312 Query: 300 AIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESI 359 A RYSAVRRQ +I ++EPE ++L++QTQQ++LFP +A AYAF F G + Y R+ + + Sbjct: 313 ATRYSAVRRQGQIDKNEPEVKVLEYQTQQHRLFPFIARAYAFQFAGAETVKLYERVLKEM 372 Query: 360 GQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACT 419 G++S + +LHALT+GLK+ T GIE+ RMACGGHGYS +S I IY CT Sbjct: 373 KSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMACGGHGYSMASYISEIYGVAIGGCT 432 Query: 420 FEGENTVMMLQTARFLMKIYDQVRSGKL--VGGMVSYLNDLPSQRIQPQQVAVWPTMVDI 477 +EGEN VM+LQ AR+L+K V+SGK +G +V+YL R +P +++D Sbjct: 433 YEGENMVMLLQLARYLVKSAALVKSGKASQLGPLVAYLG----ARSEPT------SLIDR 482 Query: 478 NSLEGLTE---AYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYV 534 G+TE ++ A R AA + + + +E+AWN +SV+L RAS H Sbjct: 483 VPNGGITEYIKTFQHIAKRQTLKAANKFFGLMENGEKREIAWNKSSVELNRASRLHTRLF 542 Query: 535 VVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILE 594 +V+ F+ ++ +I D ++ L +L L+ Y + LE ++ QL V ++ Sbjct: 543 IVEAFARRVNEIGDITIKEALSDLLHLHVNYELLDVATYALEDGFMSSTQLDYVRDQLYF 602 Query: 595 LLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHL 654 L IRPNAV+L+D+++F D L SVLGR DG+VYENLF+WAK+SPLNKT+V S +L Sbjct: 603 YLQKIRPNAVSLLDSWEFSDRELRSVLGRRDGHVYENLFKWAKESPLNKTDVLPSVDTYL 662 Query: 655 KPLQSK 660 KP+ K Sbjct: 663 KPMMEK 668 >5K3J-A nrPDB Length = 674 Score = 768 bits (1983), Expect = 0.0, Method: Composition-based stats. Identities = 279/663 (42%), Positives = 403/663 (60%), Gaps = 19/663 (2%) Query: 2 NPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQH-EDYNFLTRSQRY 60 NP+L +ER ATF+ + + ++ GS E RRRREI + + P+ + Y FLTR ++ Sbjct: 11 NPELLEERRMATFDTDKMAAVIYGSEEFARRRREITDAVSKIPELADIKPYPFLTREEKV 70 Query: 61 EVAVKKSATMVKKMREYGISDPEEIM-WFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQ 119 +K + + K + + D EE + + P L+ ++FIPTL +Q + Q Sbjct: 71 TEGTRKISILTKYLNQLIDRDNEEESLHLHREVIGYEGHPFALHDALFIPTLQSQASDEQ 130 Query: 120 QEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGG 179 QEKW+ ++ +IIG YAQTE+GHG++LR LETTA YD +QEF+L++PT T++KWWPG Sbjct: 131 QEKWLERARRREIIGCYAQTELGHGSNLRNLETTAVYDIASQEFVLHTPTTTALKWWPGA 190 Query: 180 LGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGY 239 LGK+ N+A+V+A+LI + YG H F+V +R+ TH PL G+TVGDIGPK + DNGY Sbjct: 191 LGKSCNYALVVAELIIKRNNYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMNFNAADNGY 250 Query: 240 LKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTI 299 L ++N R+PR N+LM++ +V+ DGTYVKP K+ Y MV +RS + L+ A TI Sbjct: 251 LGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAKIGYSGMVKIRSQMAMEQGLFLAHALTI 310 Query: 300 AIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESI 359 A RYSAVRRQ + + E ++LD+QTQQ++LFP LA AYAF F G Y ++ + + Sbjct: 311 AARYSAVRRQGHLDDKQVEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDV 370 Query: 360 GQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACT 419 G+ S + +LHALT+GLK+ GIE+ RMACGGHGYS +S I +Y CT Sbjct: 371 DMGNTSGMADLHALTSGLKSVVAHETGEGIEQARMACGGHGYSMASYISVVYGIAIGGCT 430 Query: 420 FEGENTVMMLQTARFLMKIYDQVRSGKL--VGGMVSYLNDLPSQRIQPQQVAVWPTMVDI 477 + GEN VM+LQ AR+L+K + +++GK +G + SYL D + D+ Sbjct: 431 YAGENMVMLLQLARYLVKSVELIKAGKAKKLGPVASYLADKSDE-------------TDL 477 Query: 478 NSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRASEAHCHYVVVK 537 SL G + ++ A R A + + +S+EVAWN ++V+L RAS H +++ Sbjct: 478 TSLNGYVKMFENMARRQAWKATEKFLKLMESGESREVAWNKSAVELTRASRLHTRLFIIE 537 Query: 538 VFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQVNARILELLT 597 F ++ +I+D V+ VL +L L+ Y + LE ++ QL V ++ L Sbjct: 538 AFMRRVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALE--FMSFTQLDYVRDQLYLYLE 595 Query: 598 LIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVHESYHKHLKPL 657 IRPNAV+LVD+F DM L SVLGR DG+VYENLF+WAK SPLN +V S K+LKP+ Sbjct: 596 KIRPNAVSLVDSFQISDMQLRSVLGRRDGHVYENLFKWAKSSPLNNADVLPSVEKYLKPM 655 Query: 658 QSK 660 K Sbjct: 656 MEK 658 >5YS9-A nrPDB Length = 708 Score = 744 bits (1920), Expect = 0.0, Method: Composition-based stats. Identities = 201/671 (29%), Positives = 315/671 (46%), Gaps = 29/671 (4%) Query: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 L ERA F + +T L G EN + + DP + + Q E AV Sbjct: 27 LAGERAKVKFPIKDMTEFLHGGEENVTMIERLMTELERDPVLNVSGDYDMPKEQLRETAV 86 Query: 65 KKSATMVKKMREYGISDPEEIMWFKKLYLANFVE-----PVGLNYSMFIPTLLNQGTTAQ 119 + A + ++ D E+ + L V+ +G++ +F+ + GT Q Sbjct: 87 ARIAALSGHWKK----DTEKEALLR-SQLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKEQ 141 Query: 120 QEKWMRPSQE--LQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWP 177 + W+R G +A TE+GHG+++ GLETTATY T EFI+N+P + KWW Sbjct: 142 YDYWVRKGAADVKGFYGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWI 201 Query: 178 GGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDN 237 GG ++ H A+L+ G+ YG+ FVV +R++ +H +PGI +GDIG K G + +DN Sbjct: 202 GGAAHSATHTACFARLLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDN 261 Query: 238 GYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKAC 297 G+++ N RIPR+NMLMKYA+V G +P +LTYG ++ R ++ ++ + Sbjct: 262 GWIQFTNVRIPRQNMLMKYAKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFI 321 Query: 298 TIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINE 357 TIA+RY+ VRRQ +PE +I+D+ Q +L PLLA YA + Y + + Sbjct: 322 TIALRYACVRRQFGTTPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTTD 381 Query: 358 SIGQGD----------LSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGI 407 + D + +L EL A +AGLKAFTTWT I++CR ACGGHGYS +G Sbjct: 382 LLQTIDPKDKGALGKAIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNGF 441 Query: 408 PNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQ 467 Y + CT+EG+N V+ L R L++ R GK +G V YL + ++ Sbjct: 442 GQAYADWVVQCTWEGDNNVLCLSMGRGLIQSCLGHRKGKPLGSSVGYLANKGLEQATLSG 501 Query: 468 VAVWPTMVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNLTSVDLVRAS 527 + V I + E + RA S + A+ S + + Sbjct: 502 RDLKDPKVLIEAWEKVANGAIQRA-------TDKFVELTKGGLSPDQAFEELSQQRFQCA 554 Query: 528 EAHCHYVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSIITGAQLSQ 587 + H +V F +++ V+ L NL L++L+ I + G FL + + Q Sbjct: 555 KIHTRKHLVTAFYERINASAKADVKPYLINLANLFTLWSIEEDSGLFLREGFLQPKDIDQ 614 Query: 588 VNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTEVH 647 V + +R DAF D + + +G YDG+VY++ F + + Sbjct: 615 VTELVNHYCKEVRDQVAGYTDAFGLSDWFINAPIGNYDGDVYKHYFAKVNQQNPAQNPRP 674 Query: 648 ESYHKHLKPLQ 658 Y L+P Sbjct: 675 PYYESTLRPFL 685 >5Y9D-A nrPDB Length = 709 Score = 725 bits (1871), Expect = 0.0, Method: Composition-based stats. Identities = 211/680 (31%), Positives = 344/680 (50%), Gaps = 41/680 (6%) Query: 4 DLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQ-HEDYNFLTRSQRYEV 62 ++ KER F +T+ L+G E T+ +I + I DP DY+ + R Sbjct: 32 EMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDPVLSVTADYDCNLQQAR--- 88 Query: 63 AVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVE-----PVGLNYSMFIPTLLNQGTT 117 K++ V + Y ++D E++ ++ L V+ + ++ ++FI ++ GT Sbjct: 89 --KQTMERVAALSPYLVTDTEKLSLWR-AQLHGMVDMSTRTRLSIHNNLFIGSIRGSGTP 145 Query: 118 AQQEKWMRP--SQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKW 175 Q + W++ Q G +A TE+GHG++L+GLETTATYD + +FI+N+P + + KW Sbjct: 146 EQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKW 205 Query: 176 WPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEM 235 W GG TS H + A+LI G+ YG FVVP+R + H G+++GDIG K G + + Sbjct: 206 WIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGV 265 Query: 236 DNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSK 295 DNG+++ N RIPR+NMLM+YA+V G KP ++LTYG ++ R ++ ++ + Sbjct: 266 DNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSKR 325 Query: 296 ACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRI 355 TIA+RY+ VRRQ E +I+D+ Q +L PLLA YA ++T++ Sbjct: 326 FLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIET 385 Query: 356 ---------NESIGQGDL----SELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYS 402 N+ + DL ++ EL A +AG+KAFTTW I+ECR ACGGHGYS Sbjct: 386 TDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYS 445 Query: 403 HSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLP--- 459 +G Y + CT+EG+N V+ L R L++ Q+ +GK VG + Y+ D Sbjct: 446 GYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQSALQILAGKHVGASIQYVGDKSKIS 505 Query: 460 -SQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVAWNL 518 + + P++ + P E L EA++ A+R + + + + + A+ Sbjct: 506 QNGQGTPREQLLSP--------EFLVEAFRT-ASRNNILRTTDKYQELVKTLNPDQAFEE 556 Query: 519 TSVDLVRASEAHCHYVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGS 578 S + + H ++ F ++ +D ++ L L L++L+ I + G FL + Sbjct: 557 LSQQRFQCARIHTRQHLISSFYARIATAKD-DIKPHLLKLANLFALWSIEEDTGIFLREN 615 Query: 579 IITGAQLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKK 638 I+T + +N+ + EL +R + L DAF D + + +G YDGNVYE F + Sbjct: 616 ILTPGDIDLINSLVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQ 675 Query: 639 SPLNKTEVHESYHKHLKPLQ 658 Y LKP Sbjct: 676 QNPATNPRPPYYESTLKPFL 695 >3B96-A nrPDB Length = 587 Score = 344 bits (882), Expect = 7e-95, Method: Composition-based stats. Identities = 87/449 (19%), Positives = 162/449 (36%), Gaps = 69/449 (15%) Query: 27 PENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIM 86 E T+ +E+ + E+ N ++ E+ + + +K++ +G+ P E+ Sbjct: 28 EEQTQFLKELVEPVSRF----FEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELG 83 Query: 87 W--FKKLYLANFVEPVGLN-----------YSMFIPTLLNQGTTAQQEKWMRPSQELQII 133 A VE VG++ S+ +L GT AQ+EK++ + + Sbjct: 84 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 143 Query: 134 GTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQL 193 + TE G+ + T+A P + + LN K W G ++ V A+ Sbjct: 144 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGS-----KLWISNGG-LADIFTVFAKT 197 Query: 194 ITQGECYG-----LHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIP 248 G + AFVV + GIT G K G + + + D R+P Sbjct: 198 PVTDPATGAVKEKITAFVV-------ERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVP 250 Query: 249 RENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRR 308 EN+L + V + N +G + + G A+++ A Sbjct: 251 SENVLGE---VGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATN---------- 297 Query: 309 QSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELP 368 +++ +I +F Q KL ++ Y + ++ ++ QG Sbjct: 298 -----RTQFGEKIHNFGLIQEKLARMVMLQYVTESMAY-------MVSANMDQG----AT 341 Query: 369 ELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMM 428 + A K F + A +EC GG G+ G+ + FEG N ++ Sbjct: 342 DFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDIL- 400 Query: 429 LQTARFLMKIYDQVRSGKLVGGMVSYLND 457 R + + + GK + G+ S L + Sbjct: 401 ----RLFVALQGCMDKGKELSGLGSALKN 425 >2Z1Q-A nrPDB Length = 577 Score = 297 bits (760), Expect = 1e-80, Method: Composition-based stats. Identities = 90/482 (18%), Positives = 167/482 (34%), Gaps = 70/482 (14%) Query: 18 LITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVK-KSATMVKKMRE 76 + + + +EI + E L R + E+ + ++ Sbjct: 17 EVPERVYTPEDFDESVKEIARTTRT--FVEREVLPLLERMEHGELELNVPLMRKAGELGL 74 Query: 77 YGISDPEEIMWF------------KKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWM 124 I PEE + F G + S+ L+ GT Q+ K++ Sbjct: 75 LAIDVPEEYGGLDLPKVISTVVAEELSGSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYL 134 Query: 125 RPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 + I Y TE G G+ +T AT + +ILN +K W G + Sbjct: 135 PKLASGEWIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNG-----VKQWISNAG-FA 188 Query: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDN 244 + V A++ GE + AF+V + PG++ G K G + + +++ Sbjct: 189 HLFTVFAKVD--GEHF--TAFLV-------ERDTPGLSFGPEEKKMGIKASSTRQVILED 237 Query: 245 YRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYS 304 ++P EN+L + + +K+ + + R L A +A ++ +Y+ Sbjct: 238 VKVPVENVLGEIGK-----------GHKIAFNVLNVGRYKLGAGAVGGAKRALELSAQYA 286 Query: 305 AVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESI----- 359 R Q I F Q KL + + YA + T I+E++ Sbjct: 287 TQRVQFG-------RPIGRFGLIQQKLGEMASRIYAAESA---VYRTVGLIDEALLGKKG 336 Query: 360 GQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACT 419 + ++ + E + +K + + ++E GG+GYS I Y Sbjct: 337 PEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGYGYSQEYPIERAYRDARINRI 396 Query: 420 FEGENTVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINS 479 FEG N + L L++ G+L L + Q+ + P+ + Sbjct: 397 FEGTNEINRLLIPGMLLRRAL---KGQLP---------LMQAAQRLQKELLEPSFEEPED 444 Query: 480 LE 481 LE Sbjct: 445 LE 446 >4L1F-A nrPDB Length = 383 Score = 296 bits (756), Expect = 3e-80, Method: Composition-based stats. Identities = 86/402 (21%), Positives = 143/402 (35%), Gaps = 64/402 (15%) Query: 52 NFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVEP------------ 99 + + + +K + + GI PEE L+ + Sbjct: 26 PTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYGGMGLDVLSYILAVEELSKVDDGTGI 85 Query: 100 -VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDP 158 + N S+ + GT Q++K++ P E +G + TE GT +TTA Sbjct: 86 TLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHVGAFGLTEPSAGTDASAQQTTAVL-- 143 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 K ++ILN + GK ++ +V A +G+ AF++ K + Sbjct: 144 KGDKYILNGSKIFITN------GKEADTYVVFAMTDKSQGVHGISAFIL-------EKGM 190 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTM 278 PG G I K G L ++ +P+EN+L K +G K L G Sbjct: 191 PGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGK------EGEGFKIAMETLDGGR- 243 Query: 279 VFVRSFLVGNAAQSLS---KACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLL 335 +G AAQ+L A A++YS R Q I FQ Q+ + + Sbjct: 244 -------IGVAAQALGIAEGALAAAVKYSKEREQFG-------RSISKFQALQFMMADMA 289 Query: 336 ATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMA 395 A YL + ++ + + E A+ K F + A + Sbjct: 290 TKIEAAR---------YLVYHAAMLKNEGKPYSEAAAMA---KCFASDVAMEVTTDAVQI 337 Query: 396 CGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 GG+GY+ +EG N VM + T+R L++ Sbjct: 338 FGGYGYTVDYPAERYMRNAKITQIYEGTNQVMRIVTSRALLR 379 >1JQI-A nrPDB Length = 388 Score = 286 bits (732), Expect = 2e-77, Method: Composition-based stats. Identities = 83/391 (21%), Positives = 144/391 (36%), Gaps = 67/391 (17%) Query: 68 ATMVKKMREYGI---SDPEEIMWFKKLYLANFVE-------------PVGLNYSMFIPTL 111 + VKKM E G+ PEE+ YLA + + +N S+++ + Sbjct: 44 TSQVKKMGELGLLAMDVPEELSGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPI 103 Query: 112 LNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVT 171 L G++ Q+++W+ P IG +A +E G+G+ TTA + ++LN Sbjct: 104 LKFGSSQQKQQWITPFTNGDKIGCFALSEPGNGSDAGAASTTAR--EEGDSWVLNGTKAW 161 Query: 172 SIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG 231 W ++ +V A + G+ AF+VP+ P PG+T+G K G Sbjct: 162 ITNSW------EASATVVFASTDRSRQNKGISAFLVPM-------PTPGLTLGKKEDKLG 208 Query: 232 YEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQ 291 L ++ RIP+EN+L + G K L G +G A+Q Sbjct: 209 IRASSTANLIFEDCRIPKENLLGEP------GMGFKIAMQTLDMGR--------IGIASQ 254 Query: 292 SLSKA---CTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYM 348 +L A A++Y+ R + Q Q+KL + + + Sbjct: 255 ALGIAQASLDCAVKYAENRHAFGA-------PLTKLQNIQFKLADMALALESARLLTWR- 306 Query: 349 KETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIP 408 ++ + + + +A K + A A + GG GY Sbjct: 307 --------AAMLKDNKKPFTK---ESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAE 355 Query: 409 NIYVTFTPACTFEGENTVMMLQTARFLMKIY 439 Y +EG + + L A L++ Y Sbjct: 356 RYYRDARITEIYEGTSEIQRLVIAGHLLRSY 386 >4N5F-A nrPDB Length = 385 Score = 286 bits (731), Expect = 2e-77, Method: Composition-based stats. Identities = 82/385 (21%), Positives = 136/385 (35%), Gaps = 64/385 (16%) Query: 67 SATMVKKMREYGISDPEEIMWFKKLYLANFVEP-------------VGLNYSMFIPTLLN 113 + ++ G+ P+E+ Y+A + + ++ S+ +L Sbjct: 49 IVAQLGELGLLGMIVPQELGGSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILG 108 Query: 114 QGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSI 173 GT AQ+++W+ ++IG + TE G+ L T A + + +++LN Sbjct: 109 FGTPAQKDRWLADMAAGRVIGAFCLTEPHAGSEANNLRTRA--ELRDGQWVLNGAKQFVT 166 Query: 174 KWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYE 233 G+ + AIV A + G+ AF+VP PG VG K G Sbjct: 167 N------GQRAGVAIVFAMTDPEAGKRGISAFLVP-------TDTPGFIVGKPEKKMGIR 213 Query: 234 EMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSL 293 D + +N IP +N+L G +K + L G +G AAQ+L Sbjct: 214 ASDTCPITFENCAIPEDNLLGNR------GEGLKIALSNLEGGR--------IGIAAQAL 259 Query: 294 S---KACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKE 350 A A RY+ R Q I + Q Q KL + A Sbjct: 260 GIARAAFDKARRYAGERVQFG-------KPIAEHQAIQQKLADMAVQINAAR-------- 304 Query: 351 TYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNI 410 + + + LP L + + K F + A + GG+GY + Sbjct: 305 ---LLVHHAAKLRTAGLPCL-SEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERH 360 Query: 411 YVTFTPACTFEGENTVMMLQTARFL 435 Y +EG + V + AR L Sbjct: 361 YRDARITQIYEGTSEVQRMVIARQL 385 >1UKW-A nrPDB Length = 379 Score = 282 bits (722), Expect = 3e-76, Method: Composition-based stats. Identities = 88/399 (22%), Positives = 145/399 (36%), Gaps = 60/399 (15%) Query: 54 LTRSQRYEVAVKKSATMVKKMREYGI---SDPEE--IMWFKKLYLANFVEPVG------- 101 L +Q Y+ + +++K+ E G+ PEE M K L E + Sbjct: 25 LPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGGMGLKMLDEVIVGEELAYACMGIY 84 Query: 102 ---LNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDP 158 + + I +L GT Q+E+++RP E + +A +E G+G+ L+T A Sbjct: 85 TIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFALSEPGNGSDAAALKTRAIR-- 142 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 + ++LN K W G + +V A + + G+ A VV + Sbjct: 143 QGDHYVLNG-----TKMWISNGG-EAEWVVVFATVNPELRHKGVVALVV-------ERGT 189 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTM 278 PG I K G L ++ ++P EN L + +G K L T Sbjct: 190 PGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGE------EGEGFKIAMQTLNK-TR 242 Query: 279 VFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATA 338 + V + VG A +A A +Y+ R I +FQ Q+KL +L Sbjct: 243 IPVAAGSVGVAR----RALDEARKYAKEREAFGE-------PIANFQAIQFKLVDMLIGI 291 Query: 339 YAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGG 398 Y + LP HA +A KA+ + A + GG Sbjct: 292 ETARMYTYYAAWLADQ-----------GLPHAHA-SAIAKAYASEIAFEAANQAIQIHGG 339 Query: 399 HGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 +GY + + +EG N + L AR ++ Sbjct: 340 YGYVREFPVEKLLRDVKLNQIYEGTNEIQRLIIARHILA 378 >5OL2-C nrPDB Length = 378 Score = 277 bits (708), Expect = 1e-74, Method: Composition-based stats. Identities = 83/407 (20%), Positives = 138/407 (33%), Gaps = 64/407 (15%) Query: 47 QHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVE-------- 98 ++E T E ++ + K GI P+E + + Sbjct: 20 ENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVC 79 Query: 99 -----PVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETT 153 + + S+ + G Q++K++RP + +G + TE GT G +TT Sbjct: 80 GTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTT 139 Query: 154 ATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIG 213 A D E+ILN + G + +V+A G+ AF+V Sbjct: 140 AVLD--GDEYILNGSKIFITNAIAG------DIYVVMAMTDKSKGNKGISAFIV------ 185 Query: 214 THKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKL 273 K PG + G K G L ++ RIP+EN+L K +G K + L Sbjct: 186 -EKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGK------EGQGFKIAMSTL 238 Query: 274 TYGTMVFVRSFLVGNAAQSLS---KACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYK 330 G +G AAQ+L A ++Y R Q + FQ Q++ Sbjct: 239 DGGR--------IGIAAQALGLAQGALDETVKYVKERVQFG-------RPLSKFQNTQFQ 283 Query: 331 LFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIE 390 L + A + ++ DL A K F TA Sbjct: 284 LADMEVKVQAARH----------LVYQAAINKDLG--KPYGVEAAMAKLFAAETAMEVTT 331 Query: 391 ECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 + GG+GY+ + + +EG + V + + L+K Sbjct: 332 KAVQLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK 378 >2PG0-A nrPDB Length = 385 Score = 275 bits (704), Expect = 3e-74, Method: Composition-based stats. Identities = 86/408 (21%), Positives = 147/408 (36%), Gaps = 67/408 (16%) Query: 46 FQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDP--EEIMWFKKLYLANFVEP---- 99 + E Y ++ + + KM E G P +E A V Sbjct: 25 LEKEAYPHYNDWEKRGIIPRSFWA---KMGENGFLCPWVDEKYGGLNADFAYSVVINEEL 81 Query: 100 ---------VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGL 150 +GL+ + P + + GT Q++KW+ ++I A TE G G+ L + Sbjct: 82 EKVGSSLVGIGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIAMTEPGAGSDLANI 141 Query: 151 ETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGE--CYGLHAFVVP 208 TTA D +I+N G ++ +V + Q + G+ VV Sbjct: 142 STTAVKD--GDYYIVNGQKTFITN------GIHADLIVVACKTDPQAKPPHRGISLLVV- 192 Query: 209 IREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKP 268 + PG T G K G D L + ++P N+L + +G Sbjct: 193 ------ERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGE------EGKGFYY 240 Query: 269 LSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQ 328 L KL +V V AAQ+ ++ ++ +Q +++ ++ +FQT Q Sbjct: 241 LMEKLQQERLV------VAIAAQTAAEVMF------SLTKQYVKQRTAFGKRVSEFQTVQ 288 Query: 329 YKLFPLLA-TAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANA 387 ++L + A FV R ++E G+ ++E+ + K + T A Sbjct: 289 FRLAEMATEIALGRTFVDRVIEE------HMAGKQIVTEV-------SMAKWWITEMAKR 335 Query: 388 GIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 E GG+GY I Y + + G N +M AR L Sbjct: 336 VAAEAMQLHGGYGYMEEYEIARRYRDIPVSAIYAGTNEMMKTIIARQL 383 >2VIG-A nrPDB Length = 391 Score = 275 bits (704), Expect = 3e-74, Method: Composition-based stats. Identities = 81/391 (20%), Positives = 134/391 (34%), Gaps = 67/391 (17%) Query: 68 ATMVKKMREYGI---SDPEEIMWFKKLYLANFVE-------------PVGLNYSMFIPTL 111 A VKKM G+ PEE+ YLA + + +N S+++ + Sbjct: 40 AAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPI 99 Query: 112 LNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVT 171 L G+ Q++ W+ P IG +A +E G+G+ TTA + ++LN Sbjct: 100 LKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAE--GDSWVLNGTKAW 157 Query: 172 SIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG 231 W ++ A+V A + + AF+VP+ P PG+T+G K G Sbjct: 158 ITNAW------EASAAVVFASTDRALQNKSISAFLVPM-------PTPGLTLGKKEDKLG 204 Query: 232 YEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQ 291 L ++ RIP++++L + G K L G +G A+Q Sbjct: 205 IRGSSTANLIFEDCRIPKDSILGEP------GMGFKIAMQTLDMGR--------IGIASQ 250 Query: 292 SLSK---ACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYM 348 +L A A+ Y+ R + Q Q+KL + + + Sbjct: 251 ALGIAQTALDCAVNYAENRMAFGA-------PLTKLQVIQFKLADMALALESARLLTWRA 303 Query: 349 KETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIP 408 A K + A A + GG GY Sbjct: 304 AMLKD------------NKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAE 351 Query: 409 NIYVTFTPACTFEGENTVMMLQTARFLMKIY 439 Y +EG + + L A L++ Y Sbjct: 352 RHYRDARITEIYEGTSEIQRLVIAGHLLRSY 382 >6FAH-C nrPDB Length = 379 Score = 274 bits (700), Expect = 9e-74, Method: Composition-based stats. Identities = 76/425 (17%), Positives = 148/425 (34%), Gaps = 62/425 (14%) Query: 28 ENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV--KKSATMVKKMREYGISDPEEI 85 + ++ + D F ++ + E ++ + K +GI P+ + Sbjct: 1 MYFSEQNKMIRKLARD--FAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSL 58 Query: 86 MWFKKLYLANFVEP-------------VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQI 132 +++ + + S+ LL GT Q EK+++P + Sbjct: 59 GGSGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKK 118 Query: 133 IGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQ 192 +A TE G G+ G+ TTA ++LN + + A++ A+ Sbjct: 119 KLAFALTEPGAGSDAGGMSTTAV--DMGDYYLLNGRKTFIT------MAPLCDDAVIYAK 170 Query: 193 LITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENM 252 G+ AF+V ++ G+++G K G + M++ ++P+EN Sbjct: 171 TDMSKGTRGISAFIVDLKSE-------GVSMGKNEHKMGLIGCATSDIIMEDVKVPKENR 223 Query: 253 LMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEI 312 L G K SN + T+ R + + A AI+Y+ R+Q Sbjct: 224 L---------GEVNKGFSNAMK--TLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFG- 271 Query: 313 KQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHA 372 +I DFQ A A+ + ++ L + + D + A Sbjct: 272 ------KRIADFQ----------AIAFMIADMATKLEAAKLLVYNAASLMDNKKNATKEA 315 Query: 373 LTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTA 432 A K + + N + GG+GY + +Y +EG + V + + Sbjct: 316 SMA--KFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVIS 373 Query: 433 RFLMK 437 L+K Sbjct: 374 GMLLK 378 >4U83-A nrPDB Length = 382 Score = 269 bits (688), Expect = 2e-72, Method: Composition-based stats. Identities = 74/385 (19%), Positives = 121/385 (31%), Gaps = 60/385 (15%) Query: 65 KKSATMVKKMREYGISDPEEIMWFKKLYLANFVE-------------PVGLNYSMFIPTL 111 + T + + G+ PEE +A + V ++ S+ + Sbjct: 44 RAELTEMGALGFLGMLAPEEWGGSDLDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPI 103 Query: 112 LNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVT 171 L GT Q+ +++ + IG +A TE G+ L+T A D ++++ Sbjct: 104 LRFGTEDQKRRFLPKMACGEWIGGFALTEPQAGSDASALKTRARLD--GDHYVIDGSKQF 161 Query: 172 SIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFG 231 GK N IV A G+ AF+VP PG V + K G Sbjct: 162 IT------SGKNGNVVIVFAVTDPAAGKKGISAFIVP-------TDTPGYEVMSVEHKLG 208 Query: 232 YEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQ 291 D L N R+P EN L +G K L G + + A Sbjct: 209 QHSSDTCALGFTNMRVPVENRLG------AEGEGYKIALANLEGGRI------GIAAQAV 256 Query: 292 SLSKACTIAIR-YSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKE 350 +++A A R Y+ R I++ Q ++L + + + Sbjct: 257 GMARAAFEAARDYARERITFG-------KPIIEHQAVAFRLADMATRIETARQMVLHAAA 309 Query: 351 TYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNI 410 + + K + A GG+GY + I Sbjct: 310 LREAGKPCL------------TEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERI 357 Query: 411 YVTFTPACTFEGENTVMMLQTARFL 435 Y +EG + V L AR L Sbjct: 358 YRDVRVCQIYEGTSDVQRLVIARGL 382 >3OWA-A nrPDB Length = 597 Score = 269 bits (687), Expect = 3e-72, Method: Composition-based stats. Identities = 102/566 (18%), Positives = 190/566 (33%), Gaps = 76/566 (13%) Query: 13 TFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV-KKSATMV 71 +F + IT +PE+ ++ D L + E +S ++ Sbjct: 16 SFLVDEITIDQVFTPEDFSSEHKMIAKTTEDFIVNE----VLPELEYLEQHEFDRSVRLL 71 Query: 72 KKMREYGI---SDPEEIMWFKKLYL------------ANFVEPVGLNYSMFIPTLLNQGT 116 K+ E G+ PEE + F G + + ++ G Sbjct: 72 KEAGELGLLGADVPEEYGGIGLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGN 131 Query: 117 TAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWW 176 Q++K++ + + YA TE G G+ G +TTA + + ++LN K W Sbjct: 132 EEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGE-----KQW 186 Query: 177 PGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMD 236 ++ IV A++ GE + AF+V K G++ K G + Sbjct: 187 ITNSA-FADVFIVYAKID--GEHF--SAFIV-------EKDYAGVSTSPEEKKMGIKCSS 234 Query: 237 NGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKA 296 L +++ +P+EN+L + + + + + + R L S +A Sbjct: 235 TRTLILEDALVPKENLLGEIGK-----------GHIIAFNILNIGRYKLGVGTVGSAKRA 283 Query: 297 CTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRIN 356 I+ +Y+ R+Q + I F Q KL + A YA + Sbjct: 284 VEISAQYANQRQQFKQ-------PIARFPLIQEKLANMAAKTYAAESSVYRTVGLFESRM 336 Query: 357 ESI-------GQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPN 409 ++ G+ + + E + K F + + ++E GG+G+ I Sbjct: 337 STLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFMAEYEIER 396 Query: 410 IYVTFTPACTFEGENTVMMLQTARFLMKIY----------DQVRSGKLVGGMVSYLNDLP 459 +Y FEG N + L ++ Q +L+ M + D P Sbjct: 397 MYRDSRINRIFEGTNEINRLIVPGTFLRKAMKGELPLLQKAQKLQEELMMMMPEEVGDEP 456 Query: 460 --SQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIA--AKNLQTHVSHRKSKEVA 515 Q+ MV + + +A LV IA NL S E A Sbjct: 457 LALQKYLVNNAKKIGLMVAGLAAQKYGKALDKEQEILVNIADIVSNLYAMESAVLRTEKA 516 Query: 516 WNLTSVDLVRASEAHCHYVVVKVFSD 541 T ++ + + + F++ Sbjct: 517 IKTTGLEKNKQKVLYTEVFCQEAFNE 542 >4M9A-A nrPDB Length = 385 Score = 267 bits (682), Expect = 1e-71, Method: Composition-based stats. Identities = 86/397 (21%), Positives = 139/397 (35%), Gaps = 58/397 (14%) Query: 52 NFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVEP------------ 99 + R + + ++ G+ P + Y+A + Sbjct: 34 PNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWGGSYTDYVAYALALEEIAAGCASCAT 93 Query: 100 -VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDP 158 V ++ S+ +LN GTT Q+E+W+R + +G ++ TE G+ L T A + Sbjct: 94 LVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTVGAFSLTEPHAGSEAHNLRTRA--EL 151 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 + ++ILN G + AIV A GL AFVVP Sbjct: 152 RDGKWILNGSKQFVTN------GARAGLAIVFAMTDPDEGKRGLSAFVVP-------TDT 198 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTM 278 PG VG K G D + ++N IP+EN+L K G +K + L G Sbjct: 199 PGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKR------GEGLKIALSNLEGGR- 251 Query: 279 VFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATA 338 +G AAQ A IA R+ ++ + I + Q KL + Sbjct: 252 -------IGIAAQ----ATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQI 300 Query: 339 YAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGG 398 A + + + LP L + + K F + A A + GG Sbjct: 301 NAAR-----------LLTHHAARLRTAGLPCL-SEASQAKLFASEMAEAVCSDAIQIHGG 348 Query: 399 HGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 +G+ + Y +EG + V + AR L Sbjct: 349 YGFLVDYEVERHYRDARITQIYEGTSEVQRMVIARQL 385 >1BUC-A nrPDB Length = 383 Score = 266 bits (679), Expect = 3e-71, Method: Composition-based stats. Identities = 77/349 (22%), Positives = 118/349 (33%), Gaps = 50/349 (14%) Query: 92 YLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLE 151 Y A + S+ + GT AQ+EK++ P E +G + TE GT G + Sbjct: 82 YDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGTKLGAFGLTEPNAGTDASGQQ 141 Query: 152 TTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIRE 211 T AT + + LN + G ++ IV A +G+ AF++ Sbjct: 142 TIATKNDDGT-YTLNGSKIFITN------GGAADIYIVFAMTDKSKGNHGITAFIL---- 190 Query: 212 IGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSN 271 PG T G K G L + ++P ENML + +G K Sbjct: 191 ---EDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGE------EGKGFKIAMM 241 Query: 272 KLTYGTMVFVRSFLVGNAAQSLS---KACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQ 328 L G +G AAQ+L A A+ YS R Q + FQ+ Sbjct: 242 TLDGGR--------IGVAAQALGIAEAALADAVEYSKQRVQFG-------KPLCKFQSIS 286 Query: 329 YKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAG 388 +KL + A L + + + A K + A Sbjct: 287 FKLADMKMQIEAARN---------LVYKAACKKQEGKPFT---VDAAIAKRVASDVAMRV 334 Query: 389 IEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 E GG+GYS + +EG N V ++ T L++ Sbjct: 335 TTEAVQIFGGYGYSEEYPVARHMRDAKITQIYEGTNEVQLMVTGGALLR 383 >5LNX-A nrPDB Length = 379 Score = 265 bits (676), Expect = 6e-71, Method: Composition-based stats. Identities = 81/428 (18%), Positives = 145/428 (33%), Gaps = 71/428 (16%) Query: 28 ENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMRE---YGISDPEE 84 + + + + ++ D F ++ ++ E + ++KKM + GI PE+ Sbjct: 1 MHVTQEQVMMRKMVRD--FARKEIA--PAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQ 56 Query: 85 IMWFKKLYLANFVEP-------------VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQ 131 ++ + + ++ S+ +L G Q+ K++ Sbjct: 57 YGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGD 116 Query: 132 IIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLA 191 +G +A TE G+ L TTA K +++LN + G ++ I A Sbjct: 117 HLGAFALTEPHSGSDAGSLRTTAIK--KNGKYLLNGSKIFITN------GGAADIYITFA 168 Query: 192 QLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPREN 251 +G+ AF+V K PG TVG K G + L DN +P N Sbjct: 169 LTAPDQGRHGISAFIV-------EKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEAN 221 Query: 252 MLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLS---KACTIAIRYSAVRR 308 +L K +G L G +G AAQ+L A A+ Y+ R Sbjct: 222 LLGK------EGDGFHIAMANLNVGR--------IGIAAQALGIAEAALEHAVDYAKQRV 267 Query: 309 QSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELP 368 Q I Q +KL + A A + + + + R Sbjct: 268 QFG-------RPIAANQGISFKLADMATRAEAARHLVYHAADLHNRGLNCGK-------- 312 Query: 369 ELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMM 428 + K F + A + GG+GY + + +EG N + Sbjct: 313 ----EASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQIYEGTNEIQR 368 Query: 429 LQTARFLM 436 L +++L+ Sbjct: 369 LIISKYLL 376 >2IX5-A nrPDB Length = 436 Score = 254 bits (649), Expect = 7e-68, Method: Composition-based stats. Identities = 75/332 (22%), Positives = 124/332 (37%), Gaps = 49/332 (14%) Query: 102 LNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQ 161 ++ S+ + T+ G+ AQ+EK++ +L + +A TE +G+ GL TTAT Sbjct: 138 VHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWALTEPDNGSDASGLGTTATK----- 192 Query: 162 EFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGI 221 + + K W G ++ I+ A+ T + ++ F+V K PG+ Sbjct: 193 --VEGGWKINGQKRWIGN-STFADLLIIFARNTTTNQ---INGFIV-------KKDAPGL 239 Query: 222 TVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFV 281 I K G + NG + + N +P E+ L P N + V Sbjct: 240 KATKIPNKIGLRMVQNGDILLQNVFVPDEDRL--------------PGVNSFQDTSKVLA 285 Query: 282 RSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAF 341 S V A Q + + I Y R + ++ P + FQ Q KL +L A Sbjct: 286 VSR-VMVAWQPIGISMGI---YDMCHRYLKERKQFGAP-LAAFQLNQQKLVQMLGNVQAM 340 Query: 342 HFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGY 401 +G + + Y + GQ L KA+ + A R GG+G Sbjct: 341 FLMGWRLCKLYETGQMTPGQASLG------------KAWISSKARETASLGRELLGGNGI 388 Query: 402 SHSSGIPNIYVTFTPACTFEGENTVMMLQTAR 433 + + P T+EG + L T R Sbjct: 389 LADFLVAKAFCDLEPIYTYEGTYDINTLVTGR 420 >3PFD-A nrPDB Length = 393 Score = 245 bits (624), Expect = 6e-65, Method: Composition-based stats. Identities = 84/432 (19%), Positives = 143/432 (33%), Gaps = 59/432 (13%) Query: 21 HILDGSP--ENTRRRREIENLILNDPDFQHEDY-NFLTRSQRYEVAVKKSATMVKKMREY 77 G+P E + E L ++ + +++ + Sbjct: 6 AAWSGNPSFELFQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNSSGFS 65 Query: 78 GISDPEEIMWFKKLYLAN-----FVEPVGLNYSM-------FIPTLLNQGTTAQQEKWMR 125 I PEE +A V V + S+ L+ +G+ +++ + Sbjct: 66 AIHVPEEYGGQGADSVATCIVIEEVARVDCSASLIPAVNKLGTMGLILRGSEELKKQVLP 125 Query: 126 PSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSN 185 + + +YA +E G+ + T A D ++ILN K W GK S Sbjct: 126 AVASGEAMASYALSEREAGSDAASMRTRAVAD--GDDWILNGS-----KCWITNGGK-ST 177 Query: 186 HAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNY 245 V+A G+ AF+V HK G TVG K G + L +N Sbjct: 178 WYTVMAVTDPDKGANGISAFMV-------HKDDEGFTVGPKERKLGIKGSPTTELYFENC 230 Query: 246 RIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSA 305 RIP + ++ + GT K T+ R + A A AI Y+ Sbjct: 231 RIPGDRIIGEP------GTGFKTALA-----TLDHTRPTIGAQAVGIAQGALDAAIAYTK 279 Query: 306 VRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLS 365 R+Q + D Q Q+ L + A + R G+GDL Sbjct: 280 ERKQFG-------RPVSDNQGVQFMLADMAMKIEAARLMVYSAAARAER-----GEGDLG 327 Query: 366 ELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENT 425 + +A K F + A + GG+GY+ + + +EG N Sbjct: 328 FI------SAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEGTNQ 381 Query: 426 VMMLQTARFLMK 437 + + +R L++ Sbjct: 382 IQRVVMSRALLR 393 >2A1T-A nrPDB Length = 421 Score = 237 bits (605), Expect = 1e-62, Method: Composition-based stats. Identities = 63/330 (19%), Positives = 114/330 (34%), Gaps = 42/330 (12%) Query: 104 YSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEF 163 S+ ++ G Q++K++ E ++ Y TE G G+ + G++T A + K E+ Sbjct: 126 NSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEY 183 Query: 164 ILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITV 223 I+N K W GK +N +LA+ + AF I E PGI + Sbjct: 184 IINGQ-----KMWITNGGK-ANWYFLLARSDPDPKAPANKAFTGFIVEA----DTPGIQI 233 Query: 224 GDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRS 283 G G D + ++ ++P+EN+L+ DG K G R Sbjct: 234 GRKELNMGQRCSDTRGIVFEDVKVPKENVLI------GDGAGFKVAM-----GAFDKTRP 282 Query: 284 FLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHF 343 + A +A A +Y+ R+ +++ Q + L + Sbjct: 283 VVAAGAVGLAQRALDEATKYALERKTFG-------KLLVEHQAISFMLAEMAMKVELARM 335 Query: 344 VGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSH 403 + + + KAF AN + GG+G++ Sbjct: 336 SYQRAAWEVDSGRRNT------------YYASIAKAFAGDIANQLATDAVQILGGNGFNT 383 Query: 404 SSGIPNIYVTFTPACTFEGENTVMMLQTAR 433 + + +EG + + L AR Sbjct: 384 EYPVEKLMRDAKIYQIYEGTSQIQRLIVAR 413 >3MDE-A nrPDB Length = 385 Score = 230 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 68/387 (17%), Positives = 133/387 (34%), Gaps = 44/387 (11%) Query: 48 HEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLN-YSM 106 +Y + +E+ + + + + G+ + + ++L + ++ Sbjct: 35 TGEYPVPLLKRAWELGLMNT-HIPESFGGLGLGIIDSCLITEELAYGCTGVQTAIEANTL 93 Query: 107 FIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILN 166 L+ G QQ+K++ E ++ Y TE G G+ + G++T A + K E+I+N Sbjct: 94 GQVPLIIGGNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKA--EKKGDEYIIN 151 Query: 167 SPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDI 226 K W GK +N +LA+ + AF I E PG+ +G Sbjct: 152 GQ-----KMWITNGGK-ANWYFLLARSDPDPKAPASKAFTGFIVEA----DTPGVQIGRK 201 Query: 227 GPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLV 286 G D + ++ R+P+EN+L +G K GT R + Sbjct: 202 EINMGQRCSDTRGIVFEDVRVPKENVL------TGEGAGFKIAM-----GTFDKTRPPVA 250 Query: 287 GNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGR 346 A +A A +Y+ R+ + + Q + L + + Sbjct: 251 AGAVGLAQRALDEATKYALERKTFG-------KLLAEHQGISFLLADMAMKVELARLSYQ 303 Query: 347 YMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSG 406 + D +A + KA+ AN + GG+G++ Sbjct: 304 RAAW----------EIDSGRRNTYYA--SIAKAYAADIANQLATDAVQVFGGNGFNTEYP 351 Query: 407 IPNIYVTFTPACTFEGENTVMMLQTAR 433 + + +EG + + AR Sbjct: 352 VEKLMRDAKIYQIYEGTAQIQRIIIAR 378 >6ES9-A nrPDB Length = 551 Score = 227 bits (579), Expect = 9e-60, Method: Composition-based stats. Identities = 84/446 (18%), Positives = 144/446 (32%), Gaps = 62/446 (13%) Query: 5 LRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAV 64 ++ ATF G E+ R+ + + + + + Q + Sbjct: 153 MQDNHGRATFGA-------TGLDEDLEMIRDQFRRYAEERVIPNA-HEWHLKDQLIPM-- 202 Query: 65 KKSATMVKKMREYGISDPEEIMWFKKLYLANFV------------EPVGLNYSMFIPTLL 112 + + ++ +G++ PEE + V +G + +L Sbjct: 203 -EIIEELAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELIL 261 Query: 113 NQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTS 172 GT AQ+ KW+ +I+ T TE G+ L L T A D + VT Sbjct: 262 CGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRDGEDW-------VVTG 314 Query: 173 IKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHK--PLPGITVGDIGPKF 230 K W +T ++ + GL F+ P PG+T G+I Sbjct: 315 NKTWITHAQRTHVMTLLARTDPETTDWRGLSMFLAEKEPGTDDDPFPTPGMTGGEIE-VL 373 Query: 231 GYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAA 290 GY M L D +RI EN+L +P + + + + R+ V + Sbjct: 374 GYRGMKEYELGFDGFRIKGENLLGG----EPGRGFKQLMETFESARIQTAARAVGVAQS- 428 Query: 291 QSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKE 350 A I +RY+ R+Q +++F KL + + Sbjct: 429 -----AAEIGMRYAVDRKQFG-------KSLIEFPRVADKLA----------MMAVEIMI 466 Query: 351 TYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNI 410 S + D +L A A K A A + GG+G++ I + Sbjct: 467 ARQLTYFSAWEKDHGRRCDLEAGMA--KLLGARVAWAAADNALQIHGGNGFALEYAISRV 524 Query: 411 YVTFTPACTFEGENTVMMLQTARFLM 436 FEG + AR L+ Sbjct: 525 LCDARILNIFEGAAEIQAQVIARRLL 550 >4KTO-A nrPDB Length = 410 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 84/423 (19%), Positives = 137/423 (32%), Gaps = 59/423 (13%) Query: 29 NTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVK-KSATMVKKMREYGISDPEEIMW 87 N EI+ L + F E L A + ++ GI+ E Sbjct: 30 NFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAHGG 89 Query: 88 FKKLYLANFVE-------------PVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIG 134 YLA+ V G + ++ + + G AQ+ +++ + +G Sbjct: 90 AGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEHVG 149 Query: 135 TYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLI 194 A +E G G+ + ++ A D + ++LN K W G ++ +V A+ Sbjct: 150 ALAMSEPGAGSDVVSMKLKA--DKRGDRYVLNGS-----KMWITN-GPDADVLVVYAKTD 201 Query: 195 TQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLM 254 G+ AF+V K PG + G K G + L + +P EN+L Sbjct: 202 PAAGPRGITAFLV-------EKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLG 254 Query: 255 KYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQ 314 G VK L + L Y +V L AA + + Y R+Q Sbjct: 255 GV------GEGVKVLMSGLDYERVVLSAGPLGIMAA-----CLDVVVPYLHERKQFGQ-- 301 Query: 315 SEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALT 374 I +FQ Q KL + T M + D E A Sbjct: 302 -----PIGEFQLMQGKLADMYVT----------MNAARAYVYAVAAACDRGETARKDAAG 346 Query: 375 AGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARF 434 L + A A E A GG+GY++ + G + + + R Sbjct: 347 CIL--YAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDAKLYEIGAGTSEIRRMLIGRE 404 Query: 435 LMK 437 L Sbjct: 405 LFA 407 >4O5M-A nrPDB Length = 390 Score = 221 bits (563), Expect = 7e-58, Method: Composition-based stats. Identities = 74/424 (17%), Positives = 135/424 (31%), Gaps = 59/424 (13%) Query: 28 ENTRRRREIENLILNDPDFQHEDYNFLTRS-QRYEVAVKKSATMVKKMREYGISDPEEIM 86 N EIE L F L R ++ GI+ PE+ Sbjct: 9 MNFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYG 68 Query: 87 WFKKLYLANFVE-------------PVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQII 133 YLA+ + G + ++ + + G+ Q+ K++ + + Sbjct: 69 GAGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHV 128 Query: 134 GTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQL 193 G A +E G G+ + ++ A + + ++LN K W G ++ +V A+ Sbjct: 129 GALAMSEPGAGSDVVSMKLAA--EKRGDRYVLNG-----NKMWITN-GPDADVLVVYAKT 180 Query: 194 ITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 G+ AF++ K G + K G + L ++ +P EN+L Sbjct: 181 DLSAGPRGISAFII-------EKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLL 233 Query: 254 MKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIK 313 +G V L + L Y R L G ++ + + Y R+Q Sbjct: 234 G------TEGKGVNVLMSGLDYE-----RVVLAGGPLGIMAACLDVVVPYVHERKQF--- 279 Query: 314 QSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHAL 373 + I +FQ Q KL + T A + R Sbjct: 280 ----DQPIGEFQLMQCKLADMYVTFNASRAYVYAVAAACDRG------------ETTRKD 323 Query: 374 TAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTAR 433 AG ++ A + + GG+GY + + G + + + R Sbjct: 324 AAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAKLYEIGAGTSEIRRMLIGR 383 Query: 434 FLMK 437 L + Sbjct: 384 ELFQ 387 >3NF4-A nrPDB Length = 387 Score = 219 bits (557), Expect = 4e-57, Method: Composition-based stats. Identities = 79/422 (18%), Positives = 132/422 (31%), Gaps = 68/422 (16%) Query: 28 ENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMW 87 E REI + +L DP R ++ E + + + PEE Sbjct: 22 ELIELTREIADKVL-DPIVD--------RHEKDETYPEGVFEQLGAAGLLSLPQPEEWGG 72 Query: 88 FKKLYLANF--VEPVGLNY----------SMFIPTLLNQGTTAQQEKWMRPSQELQIIGT 135 + Y +E + + S+ LL GT Q+++W+ + IG Sbjct: 73 GGQPYEVYLQVLEEIAARWASVAVAVSVHSLSSHPLLVFGTEEQKKRWLPGMLSGEQIGA 132 Query: 136 YAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLIT 195 Y+ +E G+ L AT +++N K W GK ++ + A+ Sbjct: 133 YSLSEPQAGSDAAALRCAATPTDGG--YVINGS-----KSWITHGGK-ADFYTLFART-- 182 Query: 196 QGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMK 255 G+ F+VP PG++ G K G + DN RI + + + Sbjct: 183 GEGSRGVSCFLVP-------ADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGE 235 Query: 256 YAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQS 315 Q ++ + + R + A A A+ Y+ R + Sbjct: 236 EGQGL-----------QIAFSALDSGRLGIAAVATGLAQAALDEAVAYANER-------T 277 Query: 316 EPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTA 375 +I+D Q + L + TYL QG + Sbjct: 278 AFGRKIIDHQGLGFLLA-------DMAAAVATARATYLDAARRRDQG-----RPYSQQAS 325 Query: 376 GLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 K T A + GG GY+ + FEG N + L AR L Sbjct: 326 IAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGL 385 Query: 436 MK 437 + Sbjct: 386 TR 387 >3MPI-A nrPDB Length = 397 Score = 217 bits (552), Expect = 1e-56, Method: Composition-based stats. Identities = 74/388 (19%), Positives = 126/388 (32%), Gaps = 63/388 (16%) Query: 60 YEVAVKKSATMVKKMREYGISDPEEIMWFKKLY-----------LANFVEPVGLNYSM-- 106 YE AV+ + ++ +G PEE +A + + +M Sbjct: 39 YEEAVRP----MGELGFFGTVIPEEYGGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEV 94 Query: 107 --FIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFI 164 T+L G+ A ++K++ + +G + TE G+ + + +TA + K ++ Sbjct: 95 LGCAYTILTYGSEALKKKYVPKLSSAEFLGGFGITEPDAGSDVMAMSSTA--EDKGDHWL 152 Query: 165 LNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVG 224 LN K W + ++ I A GL AFV+ R PGI Sbjct: 153 LNGS-----KTWISNAAQ-ADVLIYYAYTDKAAGSRGLSAFVIEPRN------FPGIKTS 200 Query: 225 DIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSF 284 ++ K G G L +DN ++P+EN+L K ++ +G++ R Sbjct: 201 NLE-KLGSHASPTGELFLDNVKVPKENILGKPGD-----------GARIVFGSLNHTRLS 248 Query: 285 LVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFV 344 AI+Y RRQ I DFQ Q + + A + Sbjct: 249 AAAGGVGLAQACLDAAIKYCNERRQFG-------KPIGDFQMNQDMIAQMAVEVEAARLL 301 Query: 345 GRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHS 404 + G + + A A K G +GYS Sbjct: 302 AYKAAAAKDEG--RLNNGLDVAMAKYAAGEAVSKC---------ANYAMRILGAYGYSTE 350 Query: 405 SGIPNIYVTFTPACTFEGENTVMMLQTA 432 + Y EG + + A Sbjct: 351 YPVARFYRDAPTYYMVEGSANICKMIIA 378 >2DVL-A nrPDB Length = 372 Score = 213 bits (543), Expect = 2e-55, Method: Composition-based stats. Identities = 76/400 (19%), Positives = 131/400 (32%), Gaps = 63/400 (15%) Query: 51 YNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYL-------------ANFV 97 Y R + ++ G++ PEE + + Sbjct: 23 YPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGLDSVTWALALEELAAADPSVA 82 Query: 98 EPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYD 157 V + + LL G+ AQ+ +++ P + IG + TE G+ + L A Sbjct: 83 VIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFCLTEPQAGSDAKSLRAEARRV 142 Query: 158 PKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKP 217 F+LN +K W G ++ +V+A+ G+ AF+V K Sbjct: 143 KGG--FVLNG-----VKSWITSAGH-AHLYVVMARTE-----KGISAFLV-------EKG 182 Query: 218 LPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGT 277 PG++ G K G ++++ +P EN+L + +G + L G Sbjct: 183 TPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGE------EGRGLAYALAGLDSG- 235 Query: 278 MVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLAT 337 R + A A IA Y+ R Q ++ + Q +K+ + Sbjct: 236 ----RVGVAAQAVGIARGAFEIAKAYAEEREQFG-------KKLKEHQAIAFKIADMHVK 284 Query: 338 AYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACG 397 A + E+ + D E L A A L A E G Sbjct: 285 IAAAR----------ALVLEAARKKDRGERFTLEASAAKLFASAAAV--EVTREAVQVLG 332 Query: 398 GHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 G+GY + Y +EG + + L AR L + Sbjct: 333 GYGYHRDYRVERYYRDAKVTEIYEGTSEIQRLVIARELYR 372 >1IVH-A nrPDB Length = 394 Score = 210 bits (533), Expect = 2e-54, Method: Composition-based stats. Identities = 78/431 (18%), Positives = 142/431 (32%), Gaps = 69/431 (16%) Query: 23 LDGSPENTRRRREIENLILND---PDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGI 79 ++G E R+ R+ L + P Q D + ++ +++ + + GI Sbjct: 10 INGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKN------LREFWKQLGNLGVLGI 63 Query: 80 SDPEE--IMWFKKLYLANFVEPV-----------GLNYSMFIPTLLNQGTTAQQEKWMRP 126 + P + L +E + G + ++ I L+ G AQ+EK++ Sbjct: 64 TAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPK 123 Query: 127 SQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNH 186 + IG A +E G+ + ++ A + K +ILN K+W G ++ Sbjct: 124 LISGEYIGALAMSEPNAGSDVVSMKLKA--EKKGNHYILNG-----NKFWITN-GPDADV 175 Query: 187 AIVLAQLITQG--ECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDN 244 IV A+ G+ AF+V K +PG + K G + L ++ Sbjct: 176 LIVYAKTDLAAVPASRGITAFIV-------EKGMPGFSTSKKLDKLGMRGSNTCELIFED 228 Query: 245 YRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYS 304 +IP N+L + V L + L +V L G + I Y Sbjct: 229 CKIPAANILGH------ENKGVYVLMSGLDLERLV-----LAGGPLGLMQAVLDHTIPYL 277 Query: 305 AVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDL 364 VR +I FQ Q K+ + A + + + + Sbjct: 278 HVREAFGQ-------KIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAK---- 326 Query: 365 SELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGEN 424 AG+ ++ A + GG+GY + + G + Sbjct: 327 --------DCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTS 378 Query: 425 TVMMLQTARFL 435 V L R Sbjct: 379 EVRRLVIGRAF 389 >4IV6-A nrPDB Length = 388 Score = 209 bits (531), Expect = 3e-54, Method: Composition-based stats. Identities = 80/429 (18%), Positives = 152/429 (35%), Gaps = 64/429 (14%) Query: 26 SPENTRRRREIENLILNDPDFQHEDYNFLTRS-QRYEVAVKKSATMVKKMREYGISDPE- 83 P + E E ++ DF + + R + ++ +K++ +G++ PE Sbjct: 1 GPGSMALTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEP 60 Query: 84 ----EIMWFKKLYLA--------NFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQ 131 + + +A + +G + + LL GT Q++K++ + Sbjct: 61 YGFGAVSMPCYVQVAEELARGWMSLAGAMGGHT-VVSKLLLLFGTEEQKQKYLPRMATGE 119 Query: 132 IIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLA 191 + T A TE G G+ L+ + T A D ++++N K W + S+ ++ Sbjct: 120 LRATMALTEPGGGSDLQAMRTVARRD--GDDYVINGS-----KTWISNA-RRSDLVALMC 171 Query: 192 QLITQGE--CYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPR 249 + + G+ +V +PG V PK GY+ +++ L + R+P Sbjct: 172 KTDPDAQPAHKGVSILLVE--------KVPGFDVSRDLPKLGYKGVESCELNFTDARVPV 223 Query: 250 ENMLMKYAQVKPDGTYVKPLSNKLTYGTM-VFVRSFLVGNAAQSLSKACTIAIRYSAVRR 308 ++L +G + L G + V R+ V A A A+RYS R Sbjct: 224 SSLLG-----DDEGRGFAQMMKGLEVGRLQVAARATGVARA------AFEDALRYSQERE 272 Query: 309 QSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELP 368 I Q+ L + YA + + + D + Sbjct: 273 SFG-------KPIWQHQSVGNMLADMGTKLYAARS----------LLLSAAEKFDAGQRC 315 Query: 369 ELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMM 428 ++ A A K F + TA + GG+GYS + + EG N + Sbjct: 316 DMEAGMA--KLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPLMIVGEGTNEIQR 373 Query: 429 LQTARFLMK 437 A+ L+ Sbjct: 374 NVIAKQLVA 382 >2JIF-A nrPDB Length = 404 Score = 208 bits (529), Expect = 7e-54, Method: Composition-based stats. Identities = 59/337 (17%), Positives = 112/337 (33%), Gaps = 52/337 (15%) Query: 102 LNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQ 161 + ++ + GT Q+ ++ + +G++ +E G G+ L+T A D + Sbjct: 113 IQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGSFCLSEAGAGSDSFALKTRA--DKEGD 169 Query: 162 EFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGI 221 ++LN K W + +V+A + G+ +F+V + PG+ Sbjct: 170 YYVLNGS-----KMWISSAEH-AGLFLVMANVDPTIGYKGITSFLV-------DRDTPGL 216 Query: 222 TVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFV 281 +G K G L +N ++P N+L + G K L G Sbjct: 217 HIGKPENKLGLRASSTCPLTFENVKVPEANILGQI------GHGYKYAIGSLNEGR---- 266 Query: 282 RSFLVGNAAQSLSKA---CTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATA 338 +G AAQ L A I Y R Q ++ DFQ Q+++ + Sbjct: 267 ----IGIAAQMLGLAQGCFDYTIPYIKERIQFG-------KRLFDFQGLQHQVAHVATQL 315 Query: 339 YAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGG 398 A + + K + + A +C GG Sbjct: 316 EAARLLTYNAARLLEAG------------KPFIKEASMAKYYASEIAGQTTSKCIEWMGG 363 Query: 399 HGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 GY+ + + +EG + + + A+ + Sbjct: 364 VGYTKDYPVEKYFRDAKIGTIYEGASNIQLNTIAKHI 400 >1RX0-A nrPDB Length = 393 Score = 205 bits (522), Expect = 4e-53, Method: Composition-based stats. Identities = 63/339 (18%), Positives = 112/339 (33%), Gaps = 48/339 (14%) Query: 100 VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPK 159 + ++ M + + G Q+ K+ P ++ +Y TE G G+ L T+A + Sbjct: 101 ISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKK--Q 157 Query: 160 TQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLP 219 +ILN G G S+ +V+ + G+ VV K P Sbjct: 158 GDHYILNGSKAF-----ISGAG-ESDIYVVMCRTG-GPGPKGISCIVV-------EKGTP 203 Query: 220 GITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMV 279 G++ G K G+ + ++ +P N + +G L G + Sbjct: 204 GLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIG------SEGQGFLIAVRGLNGGRIN 257 Query: 280 FVRSFLVGNAAQSLSKACTIAIR-YSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATA 338 + + + + A I R + VR+Q + Q Q+ L + Sbjct: 258 ------IASCSLGAAHASVILTRDHLNVRKQFGE-------PLASNQYLQFTLADMATRL 304 Query: 339 YAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGG 398 A + R + E + AL + K F T A + GG Sbjct: 305 VAARLMVR-----------NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGG 353 Query: 399 HGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 +GY + EG N VM + +R L++ Sbjct: 354 YGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 392 >2CX9-A nrPDB Length = 387 Score = 204 bits (519), Expect = 9e-53, Method: Composition-based stats. Identities = 71/392 (18%), Positives = 127/392 (32%), Gaps = 65/392 (16%) Query: 68 ATMVKKMREYGI---SDPEE--IMWFKKLYLANFVE-----------PVGLNYSMFIPTL 111 +V+K+ E+G+ PE A VE V + S+ + Sbjct: 41 WDLVRKLAEFGVFGALVPEAYGGAGLSTRLFARMVEAIAYYDGALALTVASHNSLATGHI 100 Query: 112 LNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVT 171 L G+ AQ+E ++ + +G + TE G G+ L+T A + LN Sbjct: 101 LLAGSEAQKEAFLPKLASGEALGAWGLTEPGSGSDAAALKTKAEKVEGG--WRLNGTKQF 158 Query: 172 SIKWWPGGLGKTSNHAIVLAQLI----TQGECYGLHAFVVPIREIGTHKPLPGITVGDIG 227 + G + +V+A+ + + G+ AF +P G+ VG Sbjct: 159 ITQ------GSVAGVYVVMARTDPPPSPERKHQGISAF-------AFFRPERGLKVGRKE 205 Query: 228 PKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVG 287 K G D L +++ +P E +L + + Y + + +G Sbjct: 206 EKLGLTASDTAQLILEDLFVPEEALLGERGKGF--------------YDVLRVLDGGRIG 251 Query: 288 NAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRY 347 AA ++ + + I +F+ +KL A Sbjct: 252 IAAMAVG----LGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEAARL---- 303 Query: 348 MKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGI 407 YL+ E G A K F + A +E GG+GY + Sbjct: 304 ---LYLKAAELKDAG-----RPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPV 355 Query: 408 PNIYVTFTPACTFEGENTVMMLQTARFLMKIY 439 + EG + ++ L AR L++ Sbjct: 356 ERYWRDARLTRIGEGTSEILKLVIARRLLEAV 387 >4IRN-A nrPDB Length = 416 Score = 201 bits (511), Expect = 7e-52, Method: Composition-based stats. Identities = 73/407 (17%), Positives = 142/407 (34%), Gaps = 66/407 (16%) Query: 47 QHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLA------------ 94 Q + L ++ + E+ + + + +G P + L Sbjct: 56 QQSLISDLIKNDKEEIFNRDAWQKCSEFGVHGWPIPARYGGQELDILTTAYALQGLGYGC 115 Query: 95 ---NFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLE 151 + + + LL GT Q+EK++ I ++A TE G+ + L+ Sbjct: 116 KDNGLIFAMNAHIWACEMPLLTFGTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLK 175 Query: 152 TTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIRE 211 TTA D ++ILN G ++ I+ A + GL F++ Sbjct: 176 TTAQKD--GDKYILNGYKHYVTN------GTIADLFIIFATIDPSLGKEGLTTFMI---- 223 Query: 212 IGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSN 271 K PG+ + K G + L+++N + N L + +GT + ++ Sbjct: 224 ---EKDTPGLILSKPISKMGMRTAEVPELRLENCEVSAANRLGE------EGTGLAIFNH 274 Query: 272 KLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKL 331 + + R F++ A ++ + +IRY+ +Q I FQ KL Sbjct: 275 SMEWE-----RGFILAAAVGTMERLLEQSIRYARSHKQFGQ-------AIGKFQLVANKL 322 Query: 332 FPL---LATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAG 388 + L A A+ + +MKE ++ L A A L + + Sbjct: 323 VEMKLRLENAKAYLYKVAWMKE-------------NKQMALLEASMANL--YISEAWVQS 367 Query: 389 IEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 E G +GY ++ + + + G + + + A+FL Sbjct: 368 CLEAIEIHGAYGYLTNTELERELRDAIASKFYSGTSEIQRVVIAKFL 414 >4HR3-A nrPDB Length = 415 Score = 200 bits (508), Expect = 2e-51, Method: Composition-based stats. Identities = 77/393 (19%), Positives = 130/393 (33%), Gaps = 61/393 (15%) Query: 66 KSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLN------------ 113 K+ + + DPE A E +G S+F PT+ N Sbjct: 64 KAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMG--RSLFAPTVFNCNAPDSGNMEVL 121 Query: 114 --QGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVT 171 G+ Q+E W+ P E I + TE + AT + E ++N Sbjct: 122 HRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASS-DATNMAATAVVEGDEVVING---- 176 Query: 172 SIKWWPGGLGKTSNHAIVLAQ-LITQGECYGLHAFV-VPIREIGTHKPLPGITVGDIGPK 229 KWW G+G I+ Y H+ V VP+ PGITV + P Sbjct: 177 -RKWWSTGVGHPDCKVIIFMGLTDPNAHRYARHSMVLVPM-------DTPGITVERMLPT 228 Query: 230 FGY--EEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVG 287 G+ E +G + DN R+P + + G + +L G V L+G Sbjct: 229 MGFYDEPGGHGVVSFDNVRLPADAFI------AGPGKGFEIAQGRLGPGR-VHHAMRLIG 281 Query: 288 NAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRY 347 A +L AC RR + ++ +++ + ++ Sbjct: 282 LAEVALEHAC---------RR--GLDRTAFGKPLVNLGGNRERIAD----------ARIA 320 Query: 348 MKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGI 407 + +T L + + D + + + +K A I+ GG G S+ + Sbjct: 321 INQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGLSNDFPL 380 Query: 408 PNIYVTFTPACTFEGENTVMMLQTARFLMKIYD 440 +V +G + V AR + Y Sbjct: 381 AAAWVNARALRLADGPDEVHRGVVARIELAKYA 413 >3GNC-A nrPDB Length = 399 Score = 189 bits (480), Expect = 3e-48, Method: Composition-based stats. Identities = 73/396 (18%), Positives = 133/396 (33%), Gaps = 62/396 (15%) Query: 52 NFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLY-----LANFVEP------- 99 +T + R+E + ++ G + PE+ Y +A VE Sbjct: 43 PRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRS 102 Query: 100 -VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDP 158 + + S+ + + G+ AQ+EK++ + IG + TE HG+ + T A P Sbjct: 103 MMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVP 162 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 +++ K W ++ +V A+L G + F++ K Sbjct: 163 GGY-------SLSGSKMWITN-SPIADVFVVWAKLDEDGRDE-IRGFIL-------EKGC 206 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTM 278 G++ I K G G + +D +P EN+L P ++ + + Sbjct: 207 KGLSAPAIHGKVGLRASITGEIVLDEAFVPEENIL-------PHVKGLRGP-----FTCL 254 Query: 279 VFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATA 338 R + A + IA +Y R+Q + Q Q KL + Sbjct: 255 NSARYGIAWGALGAAESCWHIARQYVLDRKQFG-------RPLAANQLIQKKLADMQT-- 305 Query: 339 YAFHFVGRYMKETYLRINESIGQGDLSELPELHAL-TAGLKAFTTWTANAGIEECRMACG 397 E L + + G + + T+ +K + A R G Sbjct: 306 -----------EITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLG 354 Query: 398 GHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTAR 433 G+G S G+ V T+EG + + L R Sbjct: 355 GNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGR 390 >3SF6-A nrPDB Length = 403 Score = 189 bits (479), Expect = 3e-48, Method: Composition-based stats. Identities = 76/419 (18%), Positives = 128/419 (30%), Gaps = 62/419 (14%) Query: 26 SPENTRRRREIENLILN--DPDFQH--EDYNFLTRSQRYEVAVKKSATMVKKMREYGISD 81 S E R + +++ P ED R E+ + ++ YG + Sbjct: 31 SAEEREIRDTVRSVVQRRIKPHIASWYEDGELPARELAVELGE--LGLLGMHLKGYGCAG 88 Query: 82 PEEI-MWFKKLYL----ANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTY 136 + L L + V + S+ + + G+ Q+++W+ IG + Sbjct: 89 MSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYAIHAFGSDEQKDQWLPDMASGHRIGCF 148 Query: 137 AQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQ 196 TE HG+ G+ T AT ++IL T K W G ++ A+V A+ Sbjct: 149 GLTEPDHGSDPAGMRTRATRS--GDDWIL-----TGTKMWITN-GSVADVAVVWARTDE- 199 Query: 197 GECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKY 256 G+ FVVP PG T I K L +D R+P L Sbjct: 200 ----GIRGFVVP-------TDTPGFTANTIKSKMSLRASVTSELVLDGVRLPDSARLPGA 248 Query: 257 AQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSE 316 + + R +V A + A+ Y+ R Q Sbjct: 249 TSLGAP------------LRCLNEARFGIVFGALGAARDCLETALAYACSREQF------ 290 Query: 317 PEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAG 376 + I FQ Q KL + + ++ + Q L +L + Sbjct: 291 -DRPIGGFQLTQQKLADMTLEYGKGFLLALHLGRQKDAGELAPEQVSLGKLNNVR----- 344 Query: 377 LKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 A R G G + + T+EG + + L + L Sbjct: 345 -------EAIEIARTARTVLGASGITGEYPVMRHANNLESVLTYEGTSEMHTLIIGQAL 396 >5IDU-A nrPDB Length = 410 Score = 186 bits (472), Expect = 2e-47, Method: Composition-based stats. Identities = 56/341 (16%), Positives = 107/341 (31%), Gaps = 47/341 (13%) Query: 104 YSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEF 163 + + GT Q+ +++ + + I +A +E G+ + + A + + Sbjct: 112 QGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAGSDVAAMSLQARAE--GDCY 169 Query: 164 ILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITV 223 +++ K W G ++ +V A+ G+ AF+V PG+ + Sbjct: 170 VIDG-----DKTWISNGG-IADFYVVFARTGEAPGARGISAFIV-------DADTPGLQI 216 Query: 224 GDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRS 283 + + L D+ R+PR ML G K T+ R+ Sbjct: 217 AERIDVIAPHPL--ARLHFDSARVPRSQMLG------APGEGFKIAM-----RTLDVFRT 263 Query: 284 FLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHF 343 + + +A + +A R+ + DFQ Q KL + T + Sbjct: 264 SVAAASLGFARRALQEGLARAASRKMFGQT-------LGDFQLTQTKLAQMALTIDSSAL 316 Query: 344 VGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSH 403 + + A K + A I+ GG G Sbjct: 317 LVYRAAWLRDQGENVTR------------EAAMAKWHASEGAQQVIDAAVQLWGGMGVQS 364 Query: 404 SSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRS 444 + + +Y +EG V L R L+K + R Sbjct: 365 GTTVERLYREIRALRIYEGATEVQQLIVGRDLLKAHAAQRQ 405 >5JSC-A nrPDB Length = 410 Score = 183 bits (463), Expect = 3e-46, Method: Composition-based stats. Identities = 57/345 (16%), Positives = 103/345 (29%), Gaps = 47/345 (13%) Query: 93 LANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLET 152 + + + + GT Q+ +++ I +A +E G+ + + Sbjct: 101 HSGLADFALAMQGLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTL 160 Query: 153 TATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREI 212 +A D ++L+ K W G ++ +V A+ G+ AFVV Sbjct: 161 SARED--GDAYVLDG-----DKTWISNGG-IADFYVVFARTGEAPGARGISAFVV----- 207 Query: 213 GTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNK 272 PG+ + + + L R+PR ML G K Sbjct: 208 --DADTPGLEIAERIDVIAPHPL--ARLHFAGARVPRSQMLG------APGEGFKLAM-- 255 Query: 273 LTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLF 332 T+ R+ + + A + +A R+ + DFQ Q KL Sbjct: 256 ---RTLDIFRTSVAAASLGFARHAMAEGVARAASRKMFGQT-------LGDFQLTQAKLA 305 Query: 333 PLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEEC 392 + T + + + A K + A I+ Sbjct: 306 QMALTIDSSALLVYRAAWLRDQGENVTR------------EAAMAKWHASEGAQQVIDAA 353 Query: 393 RMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 GG G + + +Y +EG V L R L+K Sbjct: 354 VQLYGGMGVQSGTAVEMLYREIRALRIYEGATEVQQLIVGRDLLK 398 >3R7K-A nrPDB Length = 403 Score = 179 bits (454), Expect = 3e-45, Method: Composition-based stats. Identities = 70/447 (15%), Positives = 140/447 (31%), Gaps = 61/447 (13%) Query: 3 PDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEV 62 P + + T + + + T R + + + E L + Sbjct: 2 PGSMTDAGTTTASEDGAARFVVAPEAWTTPERRALSQMARSFV-EREIAPKLAEWEHVGE 60 Query: 63 AVKKSATMVKKMREYGISDPEEIMW---------FKKLYLANFVEPVGLNYSMF-----I 108 + ++ GI PEE+ + G+ ++F + Sbjct: 61 IPRDLHLNAAEVGLLGIGFPEEVGGSGGNAIDSALVTEAILAAGGSTGVCAALFTHGIAL 120 Query: 109 PTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSP 168 P + G+ A E+++RP+ ++IG+ TE G G+ + L T A + T +++N Sbjct: 121 PHIAANGSDALIERYVRPTLAGKMIGSLGVTEPGAGSDVANLRTRAVREGDT--YVVNGA 178 Query: 169 TVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGP 228 G ++ + G YG + +V K PG V Sbjct: 179 KTFIT------SGVRADFVTTAVRT--GGPGYGGVSLLV------IDKNSPGFEVSRRLD 224 Query: 229 KFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGN 288 K G+ D L + R+P +N++ + + + + R + Sbjct: 225 KMGWRCSDTAELSFVDVRVPADNLVG------AENSGFLQIMQQFQAE-----RLGIAVQ 273 Query: 289 AAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYM 348 A + +A +A ++ R + Q ++KL + R + Sbjct: 274 AYATAGRALDLAKSWARERETFGRPLTGR-------QIIRHKLAEMARQVDVACTYTRAV 326 Query: 349 KETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIP 408 + +L ++ A + K + + + E GG GY S I Sbjct: 327 MQRWLAG------------EDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIE 374 Query: 409 NIYVTFTPACTFEGENTVMMLQTARFL 435 Y G N +M A+ + Sbjct: 375 RHYRDCRILGIGGGTNEIMNEVIAKRI 401 >3SWO-A nrPDB Length = 399 Score = 173 bits (439), Expect = 2e-43, Method: Composition-based stats. Identities = 65/336 (19%), Positives = 110/336 (32%), Gaps = 51/336 (15%) Query: 100 VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPK 159 V + S+ + ++ G+ Q+ +W+ IG + TE G++ G+ T A D Sbjct: 107 VSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLTEPDFGSNPAGMRTRARRD-- 164 Query: 160 TQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLP 219 ++ILN K W G ++ A V AQ G+ F+VP P Sbjct: 165 GSDWILNG-----TKMWITN-GNLADVATVWAQTDD-----GIRGFLVP-------TDTP 206 Query: 220 GITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMV 279 G T +I K L +DN R+P L P + + Sbjct: 207 GFTANEIHRKLSLRASVTSELVLDNVRLPASAQL-------PLAEGLSAPL-----SCLN 254 Query: 280 FVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAY 339 R +V A + + I Y+ R + + ++Q Q KL + Sbjct: 255 EARFGIVFGALGAARDSLETTIAYTQSREVF-------DKPLSNYQLTQEKLANMTVELG 307 Query: 340 AFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGH 399 + ++ Q L +L + A + ECR GG Sbjct: 308 KGMLLAIHLGRIKDAEGVRPEQISLGKLNNVREAIAIAR------------ECRTLLGGS 355 Query: 400 GYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 G + T+EG + + +L + L Sbjct: 356 GITLEYSPLRHANNLESVLTYEGTSEMHLLSIGKAL 391 >1SIR-A nrPDB Length = 394 Score = 173 bits (438), Expect = 2e-43, Method: Composition-based stats. Identities = 68/388 (17%), Positives = 132/388 (34%), Gaps = 65/388 (16%) Query: 69 TMVKKMREYGISDPEEIMWFKKLY-------LANFVEP--------VGLNYSMFIPTLLN 113 ++ +M E G+ P + LA +E + + S+ + + Sbjct: 51 EIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYA 110 Query: 114 QGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSI 173 G+ Q++K++ + +++G + TE G+ +ET A Y+ + + LN Sbjct: 111 YGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNG-----T 165 Query: 174 KWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYE 233 K W ++ +V A+ E + F++ K + G++ I KF Sbjct: 166 KTWITN-SPMADLFVVWARC----EDGCIRGFLL-------EKGMRGLSAPRIQGKFSLR 213 Query: 234 EMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSL 293 G + MD +P EN+L + + +G + R + + Sbjct: 214 ASATGMIIMDGVEVPEENVLPGASSLGGP------------FGCLNNARYGIAWGVLGAS 261 Query: 294 SKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYL 353 A +Y+ R Q + + Q Q KL +L E L Sbjct: 262 EFCLHTARQYALDRMQFGV-------PLARNQLIQKKLADMLT-------------EITL 301 Query: 354 RINESIGQGDLSELPELHALT-AGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYV 412 ++ + G L + + + LK A + R GG+G S + + Sbjct: 302 GLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAM 361 Query: 413 TFTPACTFEGENTVMMLQTARFLMKIYD 440 T+EG + + L R + I Sbjct: 362 NLEAVNTYEGTHDIHALILGRAITGIQA 389 >4W9U-A nrPDB Length = 395 Score = 173 bits (437), Expect = 3e-43, Method: Composition-based stats. Identities = 66/419 (15%), Positives = 134/419 (31%), Gaps = 66/419 (15%) Query: 28 ENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMW 87 E+ R R+ +D + ++ E + ++ + G++ PE+ Sbjct: 21 EDERMIRDSAKAFASDVLL-----PRVEKAYLEETTDPELFHLMGQAGLLGVTLPEDYGA 75 Query: 88 FKKLYLA-----NFVEP--------VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIG 134 Y+A VE + + S+ + + G+ Q++K++ ++IG Sbjct: 76 ANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGLVSGELIG 135 Query: 135 TYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLI 194 + TE G+ G++T A E I ++ K W ++ +V A+ Sbjct: 136 CFGLTEPDAGSDPAGMKTRA-------EKIDGGYRLSGSKMWISN-SPIADVFVVWAKS- 186 Query: 195 TQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLM 254 + F++ K + G++ IG K G + MD + + +L Sbjct: 187 -AAHDNAIRGFIL-------EKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAIL- 237 Query: 255 KYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQ 314 P+ + +K +G + R G + L A R RQ + + Sbjct: 238 ------PNVSGLKGP-----FGCLNRARY---GISWGVLGAAEDCWFR----ARQYGLDR 279 Query: 315 SEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALT 374 + + Q Q KL + + + + + Sbjct: 280 KQFNKPLAGTQLYQKKLADMQTEIALGIQASLRVGRLFDEGKMAPE------------MI 327 Query: 375 AGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTAR 433 + +K A + R GG+G + T+EG + V L R Sbjct: 328 SIVKRNNCGKALDIARQARDMHGGNGIQIEYHVMRHAQNLETVNTYEGTHDVHALILGR 386 >2EBA-A nrPDB Length = 385 Score = 165 bits (418), Expect = 4e-41, Method: Composition-based stats. Identities = 62/337 (18%), Positives = 112/337 (33%), Gaps = 51/337 (15%) Query: 100 VGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTH-LRGLETTATYDP 158 V + S+ + + G+ Q+ +++ +++G + TE G+ ++T A + Sbjct: 93 VSVQSSLVMYPIYAYGSEEQKREFLPKLARGEMVGCFGLTEPDGGSDPYGNMKTRARREG 152 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 T ++LN K W G ++ A++ A+ GE G F+VP Sbjct: 153 DT--WVLNG-----TKMWITN-GNLAHLAVIWAK-DEGGEVLG---FLVP-------TDT 193 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTM 278 PG ++ K L ++ R+P L P +K + LT Sbjct: 194 PGFQAREVKRKMSLRASVTSELVLEEVRVPESLRL-------PKALGLKAPLSCLTQ--- 243 Query: 279 VFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATA 338 R + A +L A+ ++ R + Q Q KL +LA Sbjct: 244 --ARFGIAWGAMGALEAVYEEAVAFAKSRSTFGE-------PLAKKQLVQAKLAEMLA-- 292 Query: 339 YAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGG 398 + + L + + + P A + K W A R GG Sbjct: 293 -------WHTEGLLLAWRLARLKDEGKLTP---AQVSLAKRQNVWKALQAARMARDILGG 342 Query: 399 HGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 G + + T+EG + V L R + Sbjct: 343 SGITLEYHAIRHMLNLETVYTYEGTHDVHTLVLGREI 379 >3P4T-A nrPDB Length = 403 Score = 164 bits (414), Expect = 1e-40, Method: Composition-based stats. Identities = 64/392 (16%), Positives = 115/392 (29%), Gaps = 59/392 (15%) Query: 58 QRYEVAVKKSATMVKKMREYGISDPEEIMWFKK---------LYLANFVEPVGLNYSMF- 107 +R ++ ++ G PE+ + P G+ S+F Sbjct: 53 ERAGEIPRELHRKAAELGLLGAGFPEDAGGSGGDGADPVVICEEMHYAGSPGGVYASLFT 112 Query: 108 ----IPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEF 163 +P ++ G + ++RP+ + IG A TE G G+ + L T A D + Sbjct: 113 CGIAVPHMIASGDQRLIDTYVRPTLRGEKIGALAITEPGGGSDVGHLRTRA--DLDGDHY 170 Query: 164 ILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITV 223 ++N G +++ + A+ G+ VV K PG V Sbjct: 171 VINGAKTYIT------SGVRADYVVTAART-GGPGAGGVSLIVV-------DKGTPGFEV 216 Query: 224 GDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRS 283 K G+ D L + R+P N++ + T ++ V R Sbjct: 217 TRKLDKMGWRSSDTAELSYTDVRVPVANLVG------SENTGFAQIAAAF-----VAERV 265 Query: 284 FLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHF 343 L A + + + + R ++ Q Q L + Sbjct: 266 GLATQAYAGAQRCLDLTVEWCRNRDTFG-------RPLISRQAVQNTLAGMARRIDVARV 318 Query: 344 VGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSH 403 R++ E L+ L A K + GG GY Sbjct: 319 YTRHVVER-----------QLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMA 367 Query: 404 SSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 S + Y G ++ A+ L Sbjct: 368 ESEVERQYRDMRILGIGGGTTEILTSLAAKTL 399 >5ZW7-A nrPDB Length = 402 Score = 163 bits (412), Expect = 2e-40, Method: Composition-based stats. Identities = 52/337 (15%), Positives = 109/337 (32%), Gaps = 45/337 (13%) Query: 99 PVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDP 158 + + + L G++ ++K++ ++I A TE G+ + ++ AT P Sbjct: 88 SLCAHLCACVIPLYRFGSSELKDKYLESLVTGKLIAANAATEPDAGSDIYNMQ--ATAQP 145 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 +ILN + ++ I+ A+ G+ AF++ K Sbjct: 146 CEGGYILNGKKIFITNAPI------ADVFIIYAKTNPDHGFLGVSAFLI-------EKGT 192 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTM 278 PG+ VG++ PK + ++ IP+ + +G + +M Sbjct: 193 PGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIG------MEGAGGAIFHD-----SM 241 Query: 279 VFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATA 338 ++ + L L++ + Y+ R+Q I FQ+ ++ + Sbjct: 242 IWEKGCLSALFVGGLARLLETTLEYAKARQQFG-------KAIGQFQSVSNRIIDMKLRL 294 Query: 339 YAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGG 398 + + + + A A K + A + GG Sbjct: 295 EQCRLMLYRACWKHDQGQ------------DAEADIAMSKLLISEYAVQSGLDAIQTFGG 342 Query: 399 HGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435 G+ + P+ F G N + AR L Sbjct: 343 AAMDQELGLVRHLLNMIPSRIFSGTNDIQKEIIARKL 379 >6CY8-B nrPDB Length = 380 Score = 158 bits (399), Expect = 7e-39, Method: Composition-based stats. Identities = 60/388 (15%), Positives = 117/388 (30%), Gaps = 62/388 (15%) Query: 65 KKSATMVKKMREYGISDPEE----IMWFKKLYLANFVEPVG-------------LNYSMF 107 + + + +G+ PE+ F L +E +G + Sbjct: 35 RDNWNALGDFGYFGLPIPEKYAKDGSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFAC 94 Query: 108 IPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNS 167 +L G+ + + + + I A +E G+ + L TTA + ++LN Sbjct: 95 SMPILEHGSETLKHQLLPDLATGRKIAANAISEASAGSDISNLATTAQKE--GDYYVLNG 152 Query: 168 PTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIG 227 G +++ +V A + G AFVVP + PGI+VG+ Sbjct: 153 GKSYVTN------GSIADYYVVYATTNKKHGYLGQTAFVVP-------RNTPGISVGNDY 199 Query: 228 PKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVG 287 K G + DN I ++ L + Q ++ +M + R L Sbjct: 200 HKLGLRSAPLNQVFFDNCTIHKDYALGREGQ-----------GARIFAASMDWERCCLFA 248 Query: 288 NAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRY 347 ++ + I Y+ R Q + I FQ +++ + + + Y Sbjct: 249 IFVGAMQRDLNQCIEYANTRMQ-------GDKTISRFQAVSHRIADMGVRLESARLMLYY 301 Query: 348 MKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGI 407 + ++ A K + + G GY + Sbjct: 302 AAWQKSQDVDNTKA------------VAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRV 349 Query: 408 PNIYVTFTPACTFEGENTVMMLQTARFL 435 N + F G + + L Sbjct: 350 NNSIKDALGSVLFSGTSDIQRELICNRL 377 >2WBI-A nrPDB Length = 428 Score = 139 bits (351), Expect = 3e-33, Method: Composition-based stats. Identities = 55/353 (15%), Positives = 110/353 (31%), Gaps = 63/353 (17%) Query: 108 IPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMG-HGTHLRGLETTATYDPKTQEFILN 166 + L G+ Q+++W+ P + I + TE + +E + D + +++N Sbjct: 124 MEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDS--YVIN 181 Query: 167 SPTVTSIKWWPGGLGKT-SNHAIVLAQLITQ--GECYGLHAFVVPIREIGTHKPLPGITV 223 KWW G G AIVL + +VP+ PG+ + Sbjct: 182 G-----KKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMN-------TPGVKI 229 Query: 224 GDIGPKFGYEE---MDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVF 280 FGY + + + + R+P N+++ +G + ++ G + Sbjct: 230 IRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLIL------GEGRGFE-----ISQGRLGP 278 Query: 281 VRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYA 340 R +A I + R + K YA Sbjct: 279 GRIHHCMRTVGLAERALQIMCERATQRIAFKKK------------------------LYA 314 Query: 341 FHFVGRY-------MKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECR 393 V + +++ L ++ D A +K + ++ Sbjct: 315 HEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAI 374 Query: 394 MACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGK 446 CGG G S + N+Y +G + V + A ++ + + K Sbjct: 375 QVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTAK 427 >5AHS-A nrPDB Length = 401 Score = 138 bits (348), Expect = 6e-33, Method: Composition-based stats. Identities = 56/344 (16%), Positives = 105/344 (30%), Gaps = 48/344 (13%) Query: 97 VEPVGLNYSMF-IPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTAT 155 + + ++ ++ I + G+ Q + +E G+ + T A Sbjct: 82 MGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDK-PAICISEPNAGSAASEMTTRA- 139 Query: 156 YDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTH 215 D +ILN K+W G G S ++ A++ G G+ AF+ + + G Sbjct: 140 -DKNGDHYILNGE-----KYWITGGG-VSKLHLIFARVFDDGVEQGIGAFITVLDDHGPE 192 Query: 216 KPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTY 275 G+ VG G + +L+ + +I + M+ +K + N Sbjct: 193 ----GLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYN---- 244 Query: 276 GTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLL 335 R A A + Y R Q + +FQ Q+ + + Sbjct: 245 ----AQRVGAGAVALGIAQCAFEEGVAYLKRREQFG-------RPLAEFQGLQWMVADMS 293 Query: 336 ATAYAFHFV---GRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEEC 392 A + ET+ IN++ K F TAN + Sbjct: 294 VQLEAARLMLRSAAVSGETFPDINKAAQ----------------AKIFAAETANKVTNDA 337 Query: 393 RMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLM 436 G GY + + G ++ Q A ++ Sbjct: 338 LQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRTQVASKIL 381 >4X28-A nrPDB Length = 400 Score = 126 bits (316), Expect = 3e-29, Method: Composition-based stats. Identities = 60/432 (13%), Positives = 132/432 (30%), Gaps = 73/432 (16%) Query: 26 SPENTRRRREIENLILN--DPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPE 83 +P+ RRE+ + P+ + E + + +++ + + + P+ Sbjct: 6 TPQQEELRRELRSYFATLMTPE-RREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPK 64 Query: 84 EIMWFKKLYL-----------ANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQI 132 E + + A P S+ PT++ GT Q+ ++ + Sbjct: 65 EYGGQGRSAMDQLIFTDEAAIAGAPVPFLTINSV-APTIMAYGTDEQKRFFLPRIAAGDL 123 Query: 133 IGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQ 192 + +E G GT L L TTA D ++++N K W L + +++ + + Sbjct: 124 HFSIGYSEPGAGTDLANLRTTAVRD--GDDYVVNGQ-----KMW-TSLIQYADYVWLAVR 175 Query: 193 LITQ----GECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIP 248 + + G+ +VP G + + G + Y + R+P Sbjct: 176 TNPESSGAKKHRGISVLIVPTTAE-------GFSWTPVHTMAGPDTSATYY---SDVRVP 225 Query: 249 RENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRR 308 N + + + K ++N+L + + V + + VR Sbjct: 226 VANRVGE------ENAGWKLVTNQLNHERVALVSPAPIFGCLR-------------EVRE 266 Query: 309 QSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELP 368 ++ + +++D + Q L + A A + + + Q + Sbjct: 267 WAQNTKDAGGTRLIDSEWVQLNLARVHAKAEVLKLINWEL---------ASSQSGPKDAG 317 Query: 369 ELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSG--------IPNIYVTFTPACTF 420 A + K F T A G + + ++ Sbjct: 318 PSPADASAAKVFGTELATEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFG 377 Query: 421 EGENTVMMLQTA 432 G N V Sbjct: 378 GGTNEVQRDIIG 389 >5EZ3-A nrPDB Length = 573 Score = 104 bits (258), Expect = 2e-22, Method: Composition-based stats. Identities = 61/361 (16%), Positives = 110/361 (30%), Gaps = 43/361 (11%) Query: 125 RPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 ++ + TE GT +R T A + +T KW+ S Sbjct: 200 PAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGG------AWRLTGHKWFMS--APMS 251 Query: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDN 244 + + LAQ GL F++P G + K G + ++ D Sbjct: 252 DAFLTLAQT-----KEGLSCFLLPRLGEKGESN--GFFFQRLKDKLGNRSNASSEVEFDG 304 Query: 245 YRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYS 304 L + + G VK + + +T + + +A + A+ +S Sbjct: 305 A-------LGQM--IGSPGEGVKTIMDMVTLTRLDCAVA-----SAGLMRSGLAEAVHHS 350 Query: 305 AVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDL 364 R +++ Q L + + + + + D Sbjct: 351 RHRHVFG-------KPLVEQPLMQRVLADMALDVAGATALSMRLARAFD-----MAASDR 398 Query: 365 SELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGEN 424 +E ++T +K + A A + E GG+GY + Y +EG Sbjct: 399 AEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSG 458 Query: 425 TVMMLQTARFLMKIYDQVRSGKLVGGMVSYLNDLPSQRIQPQQVAVWPTMVDINSLEGLT 484 VM L AR L + ++ + L I + A+ T D LT Sbjct: 459 NVMALDVARVLSRAPALFDG--VLDWISGQLGPRGQGTIDVLRAALQLTETDQGVARLLT 516 Query: 485 E 485 E Sbjct: 517 E 517 >1R2J-A nrPDB Length = 366 Score = 103 bits (256), Expect = 3e-22, Method: Composition-based stats. Identities = 58/373 (15%), Positives = 106/373 (28%), Gaps = 49/373 (13%) Query: 67 SATMVKKMREYGISDPEEIMWFKKL-YLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMR 125 A + + G+ E + + L + + V + M T+ G Q+ +++ Sbjct: 40 CAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSVMTSQGMAAWTVQRLGDAGQRATFLK 99 Query: 126 PSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSN 185 + +E G+ L + T D T V K W ++ Sbjct: 100 ELTSG-KLAAVGFSERQAGSDLSAMRTRVRLDGDT-------AVVDGHKVWTTAAA-YAD 150 Query: 186 HAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNY 245 H +V + G A VV PG+ V + G + L +D Sbjct: 151 HLVVFG-----LQEDGSGAVVVVP------ADTPGVRVERVPKPSGCRAAGHADLHLDQV 199 Query: 246 RIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSA 305 R+P +L G+ L ++ + R + L T A+ ++ Sbjct: 200 RVPAGAVLA--------GSGASLPM--LVAASLAYGRKSVAWGCVGILRACRTAAVAHAR 249 Query: 306 VRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLS 365 R Q + D Q + L V Y + + + Sbjct: 250 TREQFG-------RPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGS--------- 293 Query: 366 ELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENT 425 PE+ T K A AG G + Y EG + Sbjct: 294 --PEMVPATILAKHVAAERAAAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSE 351 Query: 426 VMMLQTARFLMKI 438 + + A+ + + Sbjct: 352 MCRVMLAQHALAL 364 >4RM7-A nrPDB Length = 391 Score = 98.0 bits (242), Expect = 1e-20, Method: Composition-based stats. Identities = 48/312 (15%), Positives = 91/312 (29%), Gaps = 47/312 (15%) Query: 129 ELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAI 188 ++ A +E G+ R + T T + T ++N + G+ + + Sbjct: 119 TGRLSYALAISEPEAGSDTRSMRTHVTREGDT--LVMNGTKMFVNN------GEYAPALL 170 Query: 189 VLAQLIT-QGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRI 247 V A T ++VP G + K G + ++ DN + Sbjct: 171 VSAYDKTGDDGEPEFSFWMVPRSAAGIYAY--------PEQKIGQSMLPFATVRFDNVEV 222 Query: 248 PRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVR 307 L ++ Y + + R F A A A+ ++ R Sbjct: 223 KESWRLKGSSKGFSQ-----------LYSLLEYGRVFTCAAALGEAQAAMEDAVAWARGR 271 Query: 308 RQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSEL 367 +I D Q Q KL + + Y R Sbjct: 272 EAFGQ-------RIADLQQVQMKLTEMEVKLTNMRNLVYGAAREYDRG------------ 312 Query: 368 PELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVM 427 A +K + A + GG GY + + +I+ +G + VM Sbjct: 313 EHKRLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQDCRGYQFADGTDEVM 372 Query: 428 MLQTARFLMKIY 439 ++ A +++ Y Sbjct: 373 VVIAAPLILEQY 384 >4Y9J-A nrPDB Length = 593 Score = 95.3 bits (235), Expect = 7e-20, Method: Composition-based stats. Identities = 55/303 (18%), Positives = 100/303 (33%), Gaps = 37/303 (12%) Query: 138 QTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQG 197 TE G+ + G T + L+ KW+ + ++ A+ LA+++ Sbjct: 190 MTEKKGGSDVAGGCDTYAVQIDKDTYRLHG-----YKWFSSAV--DADVALTLARIVDSD 242 Query: 198 EC-----YGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENM 252 GL F++ IR+ + L GI + + K G +++ L +D Sbjct: 243 GNALEGSRGLSLFLLKIRDESGN--LNGIQMVRLKNKLGTKQLPTAELLLDGA------- 293 Query: 253 LMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEI 312 ++ G V +SN + R + + + ++A YS R Sbjct: 294 --IAERIGDQGRGVAGISN-----MLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQ 346 Query: 313 KQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHA 372 QS+ + L + + + L G+ E L Sbjct: 347 TQSK-------WPLHTTTLAKMEVDTR--GSMLLLFEAARLLGLSEAGKSSDVEAMMLRL 397 Query: 373 LTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTA 432 +T LK + A + E GG GY +G+P + +EG V+ L Sbjct: 398 ITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVL 457 Query: 433 RFL 435 R Sbjct: 458 RVF 460 >3U33-A nrPDB Length = 541 Score = 93.0 bits (229), Expect = 4e-19, Method: Composition-based stats. Identities = 54/320 (16%), Positives = 92/320 (28%), Gaps = 42/320 (13%) Query: 124 MRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKT 183 + Q+ ++ TE G+ + T A + KW+ Sbjct: 170 LPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSY------RLVGHKWFFSVPQ-- 221 Query: 184 SNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMD 243 S+ +VLAQ GL F VP + I + + K G + ++ Sbjct: 222 SDAHLVLAQT-----AGGLSCFFVPRFLPDGQRNA--IRLERLKDKLGNRSNASCEVEFQ 274 Query: 244 NYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRY 303 + + +G ++ + L G M L +A + +A ++AI + Sbjct: 275 DA---------IGWLLGLEGEGIRLI---LKMGGMTRFDCALGSHA--MMRRAFSLAIYH 320 Query: 304 SAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGD 363 + R Q L + + A G + + D Sbjct: 321 AHQRHVFGN------------PLIQQPLMRHVLSRMALQLEG-QTALLFRLARAWDRRAD 367 Query: 364 LSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGE 423 E T K + E GG GY S +P +Y +EG Sbjct: 368 AKEALWARLFTPAAKFVICKRGMPFVAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGS 427 Query: 424 NTVMMLQTARFLMKIYDQVR 443 +M L R L K Sbjct: 428 GNIMCLDVLRVLNKQAGVYD 447 >4ZYJ-A nrPDB Length = 425 Score = 80.7 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 59/404 (14%), Positives = 117/404 (28%), Gaps = 67/404 (16%) Query: 34 REIENLILN-DPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFK--- 89 R + +L+ P + E + + R ++K G + PE++ Sbjct: 47 RRLLDLLERYLPALEAESRD----NDREATLPVHLFDRMRKEGVLGATVPEDLGGLGVHS 102 Query: 90 ----KLYLANFVEP-----VGLNYSMFIPTLLNQ-------GTTAQQEKWMRPSQELQII 133 L LA + L+ L+ T E +R + + Sbjct: 103 LHDVALALARIAGRDAGVALALHMQFSRGLTLDFEWRHGAPSTRPLAEDLLRQMGAGEAV 162 Query: 134 GTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQL 193 G +RG TT + LN + + H +V +L Sbjct: 163 IC------GAVKDVRG--TTVLTRATDGSYRLNGRKTLVS------MAGIATHYVVSTRL 208 Query: 194 ITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENML 253 G V + + PG+TV D G + + D + R+ +L Sbjct: 209 EEAGAP-------VRLAAPVVARTTPGLTVLDNWDGMGMRSSGSVDIVFDGCPVDRDRVL 261 Query: 254 MKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIK 313 + + + + + + VG A + A T +RR+ Sbjct: 262 PR-----GEPGVRDDAALAGQTVSSIAMLGIYVGIAEAARRIALTE------LRRRGGA- 309 Query: 314 QSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHAL 373 + + + +LF L + + + + G+ ++ Sbjct: 310 PAGVRTTVAE---IDARLFALHTAVASALTTADRLADDLSGDLAARGRAMMTPFQYA--- 363 Query: 374 TAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPA 417 K + +++C M GG GYS+S + +Y Sbjct: 364 ----KLLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVRAG 403 >3MXL-A nrPDB Length = 395 Score = 80.3 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 58/373 (15%), Positives = 94/373 (25%), Gaps = 70/373 (18%) Query: 69 TMVKKMREYGISDPEEIMWFKKLYL------------ANFVEPVGLNYSMFIPTLLNQ-- 114 K+ G + P E+ L A+ + + + L Sbjct: 46 EQFAKLGLMGATVPAELGGLGLTRLYDVATALMRLAEADASTALAWHVQLSRGLTLTYEW 105 Query: 115 --GTT---AQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPT 169 GT A E+ +R E + A G+ T D ++L+ Sbjct: 106 QHGTPPVRAMAERLLRAMAEGEAAVCGAL------KDAPGVVTELHSDGAGG-WLLSGRK 158 Query: 170 VTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPK 229 V + + H V AQ V + H+ PG+TV D Sbjct: 159 VLVS------MAPIATHFFVHAQRRDDDGS-------VFLAVPVVHRDAPGLTVLDNWDG 205 Query: 230 FGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNA 289 G + D + + +L + V V ++G Sbjct: 206 LGMRASGTLEVVFDRCPVRADELL-ERGPVGARRDAV--------LAGQTVSSITMLGIY 256 Query: 290 AQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMK 349 A A IA+ + A R EP+ L Sbjct: 257 AGIAQAARDIAVGFCAGR--------GGEPRAG---------ARALVAGLDTRLYALRTT 299 Query: 350 ETYLRINESIGQGDLSELPELHALTAG-----LKAFTTWTANAGIEECRMACGGHGYSHS 404 N DLS P+ K A A +++C GG Y+ Sbjct: 300 VGAALTNADAASVDLSGDPDERGRRMMTPFQYAKMTVNELAPAVVDDCLSLVGGLAYTAG 359 Query: 405 SGIPNIYVTFTPA 417 + +Y Sbjct: 360 HPLSRLYRDVRAG 372 >5GJ7-A nrPDB Length = 398 Score = 79.1 bits (193), Expect = 6e-15, Method: Composition-based stats. Identities = 61/418 (14%), Positives = 127/418 (30%), Gaps = 60/418 (14%) Query: 12 ATFNPELITHILDGSPENTRRRREIENLI-LNDPDFQH-EDYNFLTRSQRYEVAVKKSAT 69 A ++ + E R R++ P+ D+ F + T Sbjct: 3 AMYDIYGEAALPADVRERLRITRDLAQAFHERAPEHDRAGDFPFENIEDLKASGYVR-WT 61 Query: 70 MVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPT-LLNQGT--TAQQEKWMRP 126 + + G+S E +M + L + + + + + I L G Sbjct: 62 VPVEYGGLGLSLEEMLMHQEVLAKGDGSTALAIGWHVGILLHLRETGAFPDELFRMVCES 121 Query: 127 SQELQIIGTYAQTEMGHGTHLRG--LETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTS 184 + + TE G+ RG ETTA P +T K + L Sbjct: 122 VVKEGALINSCATEPATGSPSRGGKPETTAVKVPGGY-------RITGRKTFST-LSPAL 173 Query: 185 NHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDN 244 +V A + + + F+V + + + + G + + + + Sbjct: 174 TWIMVTATV---ADEDVVGQFLVRKED---------VEIVETWDTLGMRATGSHDIVLKD 221 Query: 245 YRIPRENML-----MKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTI 299 +P E ++ A+ +PDG+ G ++ + + +G A + A Sbjct: 222 VFVPEERVIVIQRPGVQAERRPDGS-----------GWLLHIPACYLGIALAARDFALEY 270 Query: 300 AIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESI 359 A Y + + I + + KL + A + + + R + + Sbjct: 271 AATY---------RPNTLPHPIAEVPHVEQKLGEMELKLLAARTL---LYDLARRFDAAS 318 Query: 360 GQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPA 417 + + P+ A +K T AN ++ GG S + + Y Sbjct: 319 PEERVKLQPQFGA----VKTLATNAANQVVDLAMRVVGGRSLSRALPLERYYRDVRAG 372 >3M9V-A nrPDB Length = 439 Score = 78.0 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 54/371 (14%), Positives = 105/371 (28%), Gaps = 60/371 (16%) Query: 67 SATMVKKMREYGISDPEEIMWFKKLYLANFVEP------------VGLNYSMFIPTLLNQ 114 + ++K G + P E+ L + + L+ + L Sbjct: 55 TFDALRKDGLMGATVPAELGGLGVDRLYDVAVALLAVARADASTALALHMQLSRGLTLGY 114 Query: 115 ----GTTAQQ---EKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNS 167 G + E+ +R + TT D ++L+ Sbjct: 115 EWRHGDERARTLAERILRGMVAGDAVVCSGI------KDHHTAVTTLRPDGAGG-WLLSG 167 Query: 168 PTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIG 227 + H ++ A+ L + VV + PG TV D Sbjct: 168 RKTLVS------MAPVGTHFVINARTDGTDGPPRLASPVV-------TRDTPGFTVLDNW 214 Query: 228 PKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVG 287 G + D+ IP +++LM+ P G + T + V V VG Sbjct: 215 DGLGMRASGTVDIVFDDCPIPADHVLMR----DPVGARNDAVLAGQTVSS-VSVLGVYVG 269 Query: 288 NAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRY 347 A + A +A+ R+ E Q+ + + +L+ L ATA + Sbjct: 270 VAQAAYDTAV------AALERRPEPPQAAALTLVAE---IDSRLYALRATAGSALTAADA 320 Query: 348 MKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGI 407 + ++ + + + K A + +C GG Y+ + Sbjct: 321 LSA---DLSGDMDERGRQMMRHFQC----AKLAVNRLAPEIVSDCLSLVGGASYTAGHPL 373 Query: 408 PNIYVTFTPAC 418 + Sbjct: 374 ARLLRDVQAGR 384 >3MKH-A nrPDB Length = 438 Score = 77.2 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 48/333 (14%), Positives = 99/333 (29%), Gaps = 41/333 (12%) Query: 104 YSMFIPTLLNQGTTAQQEKWMRPSQELQ--IIGTYAQTEMGHGTHLR-----GLETTATY 156 + + + Q +++ P + + + +E G + G +TTA Sbjct: 99 TGLGLTPINLAAGP-QHAEFLAPFLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARL 157 Query: 157 DPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQ----GECYGLHAFVVPIREI 212 + E+++N + + G K + A V+ + T G+ ++ + Sbjct: 158 E--GDEWVINGEKMWATNC-AGWDFKGCDLACVVCRDATTPLEEGQDPENKVMIILVTRA 214 Query: 213 GTHKPLPG-ITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSN 271 + G V G+ + +++ N R+P +N+L Q Sbjct: 215 DLDRNGEGSFEVLRHVATPGHTSVSGPHVRYTNVRVPTKNVLCPAGQ-----------GA 263 Query: 272 KLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKL 331 K+ +G + + A A++++ +L+ Q L Sbjct: 264 KVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKE------DNRGGAVPLLERQAFADLL 317 Query: 332 FPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEE 391 + A + G GD EL K F + A + Sbjct: 318 SGVKIQTEAARALTWKAAHAMEN-----GPGDYDARRELALAA---KVFCSEAAVKACTD 369 Query: 392 CRMACGGHGYSHSSGIPNIYVTFTPACTFEGEN 424 A G Y ++ T F+G N Sbjct: 370 VINAVGISAYDLQRPFSDLLNTAVVLPIFDGGN 402 >5XDD-A nrPDB Length = 414 Score = 74.5 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 61/397 (15%), Positives = 118/397 (29%), Gaps = 35/397 (8%) Query: 23 LDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDP 82 LD + E + R + + + RS + + K + E + Sbjct: 18 LDVATELAKTFRVTVRERERAGGTPKAERDAIRRSGLLTLLISKERGG---LGESWPTVY 74 Query: 83 EEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMG 142 E I A+ G ++S F + + Q+ +W + + A +E Sbjct: 75 EAIAEIASAD-ASLGHLFGYHFSNFA-YVDLFASPEQKARWYPQAVRERWFLGNASSENN 132 Query: 143 HGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQL--ITQGECY 200 H+ TAT P + +N ++ +V A G+ Sbjct: 133 A--HVLDWRVTATPLPDG-SYEINGTKAFCS------GSADADRLLVFAVTSRDPNGDGR 183 Query: 201 GLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVK 260 + A + G+ V G + D+G + + + +L QV Sbjct: 184 IVAALI--------PSDRAGVQVNGDWDSLGMRQTDSGSVTFSGVVVYPDELLGTPGQVT 235 Query: 261 PDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQ 320 S ++F +L G A +L +A + +S + ++++ +P Sbjct: 236 DAFASGSKPSLWTPITQLIFTHLYL-GIARGALEEAAHYSRSHSRPFTLAGVEKATEDPY 294 Query: 321 ILDFQTQQYKLFPLLATAYA-FHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKA 379 +L + L A A V ++E + R + + Q +L A K Sbjct: 295 VL---AIYGEFAAQLQVAEAGAREVALRVQELWERNHVTPEQR-----GQLMVQVASAKI 346 Query: 380 FTTWTANAGIEECRMACGGH-GYSHSSGIPNIYVTFT 415 T A G S G + Sbjct: 347 VATRLVIELTSRLYEAMGARAAASRQFGFDRFWRDAR 383 >2C12-A nrPDB Length = 439 Score = 71.8 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 52/344 (15%), Positives = 104/344 (30%), Gaps = 54/344 (15%) Query: 102 LNYSMFIPTLLNQGTTAQQEKWMRPSQ--ELQIIGTYAQTEMGHGTH-----LRGLETTA 154 + ++ + ++ + + QEK+++P E + + + +E + GL+TTA Sbjct: 95 VATALGLMPVILCDSPSLQEKFLKPFISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTA 154 Query: 155 TYDPKTQEFILNSPTVTSIKWWPGGLG----KTSNHAIVLAQLITQGECY---------G 201 + N ++ K WP G K ++ A V+ ++ Sbjct: 155 RK-------VGNEWVISGEKLWPSNSGGWDYKGADLACVVCRVSDDPSKPQDPNVDPATQ 207 Query: 202 LHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGY-LKMDNYRIPRENMLMKYAQVK 260 + +V I +K +G P+ +G + + +P EN+L Sbjct: 208 IAVLLVTRETIANNKKDAYQILG--EPELAGHITTSGPHTRFTEFHVPHENLLCTPGLKA 265 Query: 261 PDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQ 320 + G M +G A + +A A + Sbjct: 266 QGLVETAFAMSAALVGAMA------IGTARAAFEEALVFA----------KSDTRGGSKH 309 Query: 321 ILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAF 380 I++ Q+ KL + T + E + K + Sbjct: 310 IIEHQSVADKLIDCKIRLETSRLLVWKAVTTLED--------EALEWKVKLEMAMQTKIY 361 Query: 381 TTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGEN 424 TT A + + A G Y+ P + F+G N Sbjct: 362 TTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGN 405 >4XVX-A nrPDB Length = 389 Score = 65.7 bits (158), Expect = 6e-11, Method: Composition-based stats. Identities = 55/358 (15%), Positives = 103/358 (28%), Gaps = 59/358 (16%) Query: 83 EEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRP----SQELQIIGTYAQ 138 E +L A V L+ S I L G + ++R + + Sbjct: 69 ELAFALGQLASAGIGVGVSLHDS-AIAILRRFG----KSDYLRDICDQAIRGAAVLCIGA 123 Query: 139 TEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGE 198 +E G+ L+ +ET E V +K + + +V + Sbjct: 124 SEESGGSDLQIVETEIRSRDGGFE-------VRGVKKFVSLSPIADHIMVVARSVDHDPT 176 Query: 199 CYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQ 258 + VV + P K G +D + +D + +P + ++ + Sbjct: 177 SRHGNVAVVAVPAAQVSVQTP-------YRKVGAGPLDTAAVCIDTW-VPADALVARAGT 228 Query: 259 VKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPE 318 +++G + R + G A S +A I + RRQ Sbjct: 229 ----------GLAAISWG-LAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQT----- 272 Query: 319 PQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLK 378 + + Q + ++ L A + ++ QG L + Sbjct: 273 --LFEHQALRLRMADLQARVDLLRYA----------LHGIAEQGRLELRTAAAVKVTAAR 320 Query: 379 AFTTWTANAGIEECRMACGGHGYSH-SSGIPNIYVTFTPACTFEGENTVM-MLQTARF 434 I EC GG GY + + + A G + V+ L A Sbjct: 321 -----LGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGM 373 >4JEK-A nrPDB Length = 453 Score = 64.9 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 43/310 (13%), Positives = 81/310 (26%), Gaps = 26/310 (8%) Query: 108 IPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNS 167 P + G+ Q+E + A +E + +H+ + +AT ++LN Sbjct: 137 APMIELIGSQEQEEHLYTQIAQNNWWTGNASSE--NNSHVLDWKVSATPTEDGG-YVLNG 193 Query: 168 PTVTSIKWWPGGLGKTSNHAIVLAQL-ITQGECYGLHAFVVPIREIGTHKPLPGITVGDI 226 K S+ V + + + A +P G+T D Sbjct: 194 TKHFCS------GAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRA-------GVTPNDD 240 Query: 227 GPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLV 286 G + D+G N ++ + +L +V + + Sbjct: 241 WAAIGMRQTDSGSTDFHNVKVEPDEVLG------APNAFVLAFIQSERGSLFAPIAQLIF 294 Query: 287 GNAAQSLSK-ACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVG 345 N ++ A A Y+ R Q+ Q + Sbjct: 295 ANVYLGIAHGALDAAREYT--RTQARPWTPAGIQQATEDPYTIRSYGEFTIALQGADAAA 352 Query: 346 RYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSS 405 R + + + EL +G+KA T A G G Sbjct: 353 REAAHLLQTVWDKGDALTPEDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRY 412 Query: 406 GIPNIYVTFT 415 G + Sbjct: 413 GFDRFWRNVR 422 >4X28-D nrPDB Length = 373 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 55/398 (13%), Positives = 114/398 (28%), Gaps = 70/398 (17%) Query: 56 RSQRYEVAVKKSATMVKKMREYGI---SDPEEIMWFKKLYLANFVEPVGL-NY------- 104 + + ++ + + +K+ + GI + PE + L V L + Sbjct: 29 QRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVPYL 88 Query: 105 ---SMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQT-EMGHGTHLRGLETTATYDPKT 160 + L G+ Q+ W + I T A EMG G ++ T Sbjct: 89 ESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGP-VQAAGT-------- 139 Query: 161 QEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPG 220 + +T + G G ++ +V A+ + G F+V + PG Sbjct: 140 ----GHGYRLTGTRTQVG-YGPVADAFLVPAETDS-----GAAVFLVAAGD-------PG 182 Query: 221 ITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVF 280 + V + G + + L+++ ++ + GT G Sbjct: 183 VAVTALATT-GLGSVGH--LELNGAKVDAARRVGGTDVAVWLGTLSTLSRTAFQLGV--- 236 Query: 281 VRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYA 340 L + + Y+ R Q + I FQ +L Sbjct: 237 ------------LERGLQMTAEYARTREQF-------DRPIGSFQAVGQRLAD--GYIDV 275 Query: 341 FHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHG 400 + + +S+ + + ++ TAG + + GG G Sbjct: 276 KGLRLTLTQAAWRVAEDSLASRECPQPADIDVATAG--FWAAEAGHRVAHTIVHVHGGVG 333 Query: 401 YSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKI 438 + ++ G T + + R L + Sbjct: 334 VDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAET 371 >5LVW-A nrPDB Length = 413 Score = 46.0 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 49/272 (18%), Positives = 83/272 (30%), Gaps = 44/272 (16%) Query: 153 TATYDPKTQEFILNSPTVTSIKWWPGGLGK-TSNHAIVLAQ-LITQGECYGLHAFVVPIR 210 TA P + L WP G G + AI++A+ + GE G + +VP R Sbjct: 144 TAVRTPGG--YRLTGS-------WPYGTGILHDDWAILVAREVDADGEPVGGLSMLVPAR 194 Query: 211 EIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGT---YVK 267 + +TV D G + + + + +P ++ Q + + Sbjct: 195 D---------LTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGELQRSRESATDLGLP 245 Query: 268 PLSNKLTYGTMVFVRSFLVGNAAQS-----LSKACTIAIRYSAVRRQSEIKQSEPEPQIL 322 PL M V + +V A Q+ + KA T I S RQ Sbjct: 246 PLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQ------------T 293 Query: 323 DFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTT 382 D +T L + A SEL + + T Sbjct: 294 DSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSLVT 353 Query: 383 WTANAGIEECRMACGGHGYSHSSGIPNIYVTF 414 ++E A G ++ S+ + + Sbjct: 354 TA----LDELLWAHGAASFAESNPLQRYWRDA 381 >3AFF-A nrPDB Length = 394 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 42/279 (15%), Positives = 84/279 (30%), Gaps = 28/279 (10%) Query: 149 GLETTATYDPKTQEFILNSPTVTSIKW-WPGGLGKTSNHAIVLAQLITQGECYGLHAFVV 207 +++Y P +++ + + W W G ++ V +I G +F++ Sbjct: 113 STRISSSYAPMGAGVVVDGGYLVNGSWNWSSGCDH-ASWTFVGGPVIKDGRPVDFGSFLI 171 Query: 208 PIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTY-- 265 P E + D+ G + L + + +PR L A Sbjct: 172 PRSE---------YEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLA 222 Query: 266 -VKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDF 324 K+ +GTM + A + + VR ++++ +P Sbjct: 223 TNSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDP----- 277 Query: 325 QTQQYKLFPLLATAYAFHFV-GRYMKETYLRINESIGQGDLSELP-ELHALTAGLKAFTT 382 F + A A + + + +E E+P EL A + T Sbjct: 278 -------FAKVRIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRAT 330 Query: 383 WTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFE 421 + A I+ A G S+ + I + Sbjct: 331 GRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHA 369 >2RFQ-A nrPDB Length = 394 Score = 34.8 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 46/303 (15%), Positives = 95/303 (31%), Gaps = 50/303 (16%) Query: 99 PVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDP 158 +G++ L AQ++ W G+ T +R + A Sbjct: 88 IIGVHNW----HLALFSQQAQEDVW------------------GNDTDVRISSSYAPM-- 123 Query: 159 KTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPL 218 + + TV W G ++ A++ +I G +F++P + Sbjct: 124 GAGQVVDGGYTVNGAWAWSSGCDH-ASWAVLGGPVIKDGRPVDFVSFLIPRED------- 175 Query: 219 PGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQ---VKPDGTYVKPLSNKLTY 275 + D+ G + + +++ +P +L A P K+ + Sbjct: 176 --YRIDDVWNVVGLRGTGSNTVVVEDVFVPTHRVLSFKAMSNLTAPGLERNTAPVYKMPW 233 Query: 276 GTM--VFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQI------LDFQTQ 327 GT+ + + +VG A + + E + +P ++ D Sbjct: 234 GTIHPTTISAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEASSDIDAA 293 Query: 328 QYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANA 387 +L +A YA G + LR+ Q + A+++ K F + A A Sbjct: 294 WRQLSGNVADEYALLVAGEEV-PFELRLRARRDQVRATG----RAISSIDKLFESSGATA 348 Query: 388 GIE 390 Sbjct: 349 LAN 351 >2GQD-A nrPDB Length = 437 Score = 30.2 bits (66), Expect = 2.9, Method: Composition-based stats. Identities = 25/166 (15%), Positives = 44/166 (26%), Gaps = 18/166 (10%) Query: 153 TATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREI 212 A K + +N T I W G + + + + F VP+ Sbjct: 105 AAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIP 164 Query: 213 GTHKPLPGITVGDIGPKFG-YEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSN 271 I +G GP G N + + ++ G Sbjct: 165 DMATGQVSIDLGAKGPNGATVTACATG-----------TNSIGEAFKIVQRG----DADA 209 Query: 272 KLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEP 317 +T GT + + A S S+A + R + + Sbjct: 210 MITGGTEAPI--THMAIAGFSASRALSTNDDIETACRPFQEGRDGF 253 >6CU3-A nrPDB Length = 336 Score = 30.2 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 30/87 (34%), Gaps = 7/87 (8%) Query: 323 DFQTQQ------YKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAG 376 DFQ QQ ++ A+ K + + G + + L A AG Sbjct: 15 DFQQQQPTTGIHEEMLKDGIRTNAYKNAILQNKHLFKD-KVVLDIGCGTGILCLFAAKAG 73 Query: 377 LKAFTTWTANAGIEECRMACGGHGYSH 403 K + I++ R +GYSH Sbjct: 74 AKRVIGIDMSDIIDKARQIVSDNGYSH 100 >6CG0-N nrPDB Length = 126 Score = 30.2 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%), Gaps = 2/40 (5%) Query: 194 ITQGECYGLHAFVVPIRE--IGTHKPLPGITVGDIGPKFG 231 AF + E PG+++GD+ K G Sbjct: 77 DPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLG 116 >6CIM-N nrPDB Length = 163 Score = 29.8 bits (65), Expect = 4.0, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%), Gaps = 2/40 (5%) Query: 194 ITQGECYGLHAFVVPIRE--IGTHKPLPGITVGDIGPKFG 231 AF + E PG+++GD+ K G Sbjct: 91 DPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLG 130 >2GZK-A nrPDB Length = 159 Score = 29.4 bits (64), Expect = 4.8, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%), Gaps = 2/40 (5%) Query: 194 ITQGECYGLHAFVVPIRE--IGTHKPLPGITVGDIGPKFG 231 AF + E PG+++GD+ K G Sbjct: 85 DPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLG 124 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.118 0.284 Lambda K H 0.267 0.0362 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,556,530 Number of Sequences: 36641 Number of extensions: 750807 Number of successful extensions: 2368 Number of sequences better than 10.0: 78 Number of HSP's better than 10.0 without gapping: 89 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 1991 Number of HSP's gapped (non-prelim): 137 length of query: 661 length of database: 10,336,785 effective HSP length: 103 effective length of query: 558 effective length of database: 6,562,762 effective search space: 3662021196 effective search space used: 3662021196 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.7 bits)