BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07862 (306 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4C5A-A nrPDB 619 e-178 5BPF-A nrPDB 441 e-124 5D8D-A nrPDB 308 3e-84 4EGJ-A nrPDB 305 1e-83 4EG0-A nrPDB 299 1e-81 5NRH-A nrPDB 294 3e-80 3R5X-A nrPDB 195 2e-50 4FU0-A nrPDB 192 1e-49 2I87-A nrPDB 189 1e-48 3I12-A nrPDB 184 3e-47 2FB9-A nrPDB 177 4e-45 3E5N-A nrPDB 167 5e-42 3K3P-A nrPDB 166 1e-41 3LWB-A nrPDB 157 6e-39 1E4E-B nrPDB 154 6e-38 6DGI-A nrPDB 131 5e-31 1EHI-A nrPDB 123 1e-28 3TQT-A nrPDB 110 6e-25 2PVP-A nrPDB 87 9e-18 3VOT-A nrPDB 59 3e-09 3OUU-A nrPDB 53 2e-07 3LN7-A nrPDB 48 5e-06 3ORR-A nrPDB 43 1e-04 2C00-A nrPDB 42 3e-04 4RZQ-A nrPDB 40 0.001 5KS8-A nrPDB 39 0.003 1ULZ-A nrPDB 38 0.006 2YL2-A nrPDB 37 0.010 2XD4-A nrPDB 37 0.012 3U9T-A nrPDB 36 0.020 3JZF-A nrPDB 36 0.025 2DZD-A nrPDB 35 0.046 3ELE-A nrPDB 34 0.080 3MJF-A nrPDB 34 0.082 3LN6-A nrPDB 33 0.11 2IP4-A nrPDB 33 0.17 1GSO-A nrPDB 32 0.26 3WO0-A nrPDB 32 0.41 3AW8-A nrPDB 31 0.52 1W93-A nrPDB 31 0.71 3QEF-A nrPDB 30 0.89 2QK4-A nrPDB 30 1.0 4ROS-A nrPDB 30 1.6 3TR5-A nrPDB 29 2.1 5UCM-A nrPDB 28 6.9 4WD3-A nrPDB 27 8.1 5CJH-A nrPDB 27 8.7 >4C5A-A nrPDB Length = 330 Score = 619 bits (1596), Expect = e-178, Method: Compositional matrix adjust. Identities = 306/306 (100%), Positives = 306/306 (100%) Query: 1 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI 60 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI Sbjct: 25 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI 84 Query: 61 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA 120 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA Sbjct: 85 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA 144 Query: 121 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE 180 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE Sbjct: 145 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE 204 Query: 181 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL 240 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL Sbjct: 205 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL 264 Query: 241 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR 300 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR Sbjct: 265 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR 324 Query: 301 ILELAD 306 ILELAD Sbjct: 325 ILELAD 330 >5BPF-A nrPDB Length = 306 Score = 441 bits (1134), Expect = e-124, Method: Compositional matrix adjust. Identities = 222/306 (72%), Positives = 252/306 (82%) Query: 1 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI 60 M +K+AVLLGGTSAEREVSL SG AVLAGL+E GIDAY VD K+ VTQLK GF KVFI Sbjct: 1 MAEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFI 60 Query: 61 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA 120 ALHGRGGEDGTLQG+LE + LPYTGSGVMASAL+MDKLR+KL+WQ GLP++P+VAL R Sbjct: 61 ALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQ 120 Query: 121 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE 180 +FE ++ +A ++ LGLP+IVKPS EGSSVGMSKV + LQ AL AFQHD +VLIE Sbjct: 121 QFETLSPEELVACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKALVEAFQHDSDVLIE 180 Query: 181 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL 240 KWLSGPEFTVAILG+E+LPSIRIQP G FYDY+AKYLSD+TQYFCP+GL E L AL Sbjct: 181 KWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAAL 240 Query: 241 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR 300 L+A+ L C GWGR+DVM D DG FYLLE NTSPGMTSHSLVPMAARQ G+SFSQLV R Sbjct: 241 ALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVAR 300 Query: 301 ILELAD 306 IL LAD Sbjct: 301 ILMLAD 306 >5D8D-A nrPDB Length = 308 Score = 308 bits (788), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 160/302 (52%), Positives = 205/302 (67%), Gaps = 11/302 (3%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVLLGG SAER VSL+SG AVL L G+ A DP++ VT+L + + + FI LH Sbjct: 9 KVAVLLGGKSAERAVSLDSGQAVLDALLRSGVQAEAFDPQDRSVTEL--VNYDRAFIVLH 66 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 GRGGEDG +QG+LE + +PYTG+GV SA+ MDK+++K +WQG+ LP AP+ +T+ E Sbjct: 67 GRGGEDGQIQGVLEWLNIPYTGTGVQGSAIGMDKVKTKQIWQGSDLPTAPYRIITK---E 123 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 L D +AE LGLPVI+KP EGSSVGMSKV A+ A QHD V+ EKW+ Sbjct: 124 TDL-DSVIAE---LGLPVIIKPVHEGSSVGMSKVEKAEDFAAAIEKATQHDAVVMAEKWI 179 Query: 184 SGPEFTVAILGEEILPSIRIQPSG--TFYDYEAKYLSDETQYFCPAGLEASQEANLQALV 241 +G EFT++ L + LP IR+QP FYDYEAKY ++ +Y P GL ++E LQAL Sbjct: 180 TGREFTISFLNGQPLPVIRLQPPADVAFYDYEAKYQRNDVEYGIPCGLSETEEKKLQALC 239 Query: 242 LKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRI 301 L+A+ +G +GWGRID M D G F+LLE NT PGMTSHSLVP AA+ G SF +L V I Sbjct: 240 LRAFQAVGAEGWGRIDAMQDEQGNFWLLEVNTVPGMTSHSLVPKAAKAVGYSFDELCVAI 299 Query: 302 LE 303 LE Sbjct: 300 LE 301 >4EGJ-A nrPDB Length = 334 Score = 305 bits (782), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 158/302 (52%), Positives = 205/302 (67%), Gaps = 4/302 (1%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVLLGG SAEREVSLNSG VL GLR+ GIDA+P DP E + LK GF + F ALH Sbjct: 32 KVAVLLGGNSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAERPLAALKEEGFVRAFNALH 91 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 G GE+G +QG L+ G+ YTGSGV+ SAL +DK R+KL+WQ G+P P+ A+ R + Sbjct: 92 GGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQLGIPTPPFEAVLRGDDY 151 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 + + + +A+ LGLP+ VKP+ EGSSV + KV + +AL AL A + D V++EK + Sbjct: 152 EARAKEIVAK---LGLPLFVKPASEGSSVAVIKVKSADALPAALIEAVKFDRIVVVEKSI 208 Query: 184 S-GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 G E+T I G LP IRI P+G FYDY AKY++++TQY P GL A +EA L+ L Sbjct: 209 EGGGEYTACIAGNLDLPVIRIVPAGEFYDYHAKYIANDTQYLIPCGLTADEEARLKVLAR 268 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 +A+ LGC WGR D MLD+DG Y LE NT+PGMT HSL P AAR G+S+ +LVV +L Sbjct: 269 RAFDVLGCTDWGRADFMLDADGNPYFLEVNTAPGMTDHSLPPKAARAVGISYQELVVAVL 328 Query: 303 EL 304 L Sbjct: 329 AL 330 >4EG0-A nrPDB Length = 317 Score = 299 bits (765), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 152/302 (50%), Positives = 201/302 (66%), Gaps = 4/302 (1%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVL GG SAEREVSL SG VL GLR+ GIDA+P DP E ++ LK GF + F ALH Sbjct: 15 KVAVLFGGESAEREVSLTSGRLVLQGLRDAGIDAHPFDPAERPLSALKDEGFVRAFNALH 74 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 G GE+G +QG L+ G+ YTGSGV+ SAL +DK R+KL+WQ G+P P+ + R + Sbjct: 75 GGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGVPTPPFETVMRGD-- 132 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 + + ++ LGLP+ VKP+ EGSSV + KV +AL AL A HD+ V++EK + Sbjct: 133 -DYAARATDIVAKLGLPLFVKPASEGSSVAVLKVKTADALPAALSEAATHDKIVIVEKSI 191 Query: 184 SGP-EFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 G E+T I G+ LP I+I P+G FYDY AKY++++TQY P GL A QE L+ + Sbjct: 192 EGGGEYTACIAGDLDLPLIKIVPAGEFYDYHAKYVANDTQYLIPCGLPAEQETELKRIAR 251 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 +A+ LGC WGR D MLD+ G Y LE NT+PGMT HSL P AAR G+ +S+LVV++L Sbjct: 252 RAFDVLGCTDWGRADFMLDAAGNAYFLEVNTAPGMTDHSLPPKAARSIGIGYSELVVKVL 311 Query: 303 EL 304 L Sbjct: 312 SL 313 >5NRH-A nrPDB Length = 312 Score = 294 bits (753), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 152/302 (50%), Positives = 205/302 (67%), Gaps = 4/302 (1%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVLLGG SAEREVSLNSG VL GLR+ GIDA+P DP + + LK GF + F ALH Sbjct: 11 KVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALH 70 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 G GE+G +QG L+ G+ YTGSGV+ SAL +DK R+KL+WQ G+P P+ + R + Sbjct: 71 GGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDY 130 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 + +A+ LG+P+ VKP+ EGSSV + KV + +AL AL A +HD+ V++EK + Sbjct: 131 AARAQDIVAK---LGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSI 187 Query: 184 S-GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 G E+T I + LP IRI P+G FYDY AKY++++TQY P GL+A++EA + + Sbjct: 188 EGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIAR 247 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 +A+ LGC WGR D MLD+ G Y LE NT+PGMT HSL P AAR G+ +S+LVV++L Sbjct: 248 RAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVL 307 Query: 303 EL 304 L Sbjct: 308 SL 309 >3R5X-A nrPDB Length = 307 Score = 195 bits (495), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 110/301 (36%), Positives = 175/301 (58%), Gaps = 10/301 (3%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE-VDVTQLKSMGFQKVFIAL 62 +I V++GG S+E++VS+ +G ++A L + + P+ E +D+ + K+ +AL Sbjct: 5 RIGVIMGGVSSEKQVSIMTGNEMIANLDKNKYEIVPITLNEKMDLIE-KAKDIDFALLAL 63 Query: 63 HGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEF 122 HG+ GEDGT+QG LE +G+PY+GS +++S + MDK SK + + G+ W+ LT+ E Sbjct: 64 HGKYGEDGTVQGTLESLGIPYSGSNMLSSGICMDKNISKKILRYEGIETPDWIELTKME- 122 Query: 123 EKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKW 182 D E+ LG P++VKP+ GSSVG+ V ++ L L F+ D EV+IEK+ Sbjct: 123 -----DLNFDELDKLGFPLVVKPNSGGSSVGVKIVYDKDELISMLETVFEWDSEVVIEKY 177 Query: 183 LSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 + G E T +I + LP I I+ + F+DY AKY D + L A + + L Sbjct: 178 IKGEEITCSIFDGKQLPIISIRHAAEFFDYNAKY-DDASTIEEVIELPAELKERVNKASL 236 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 + L C + R+D+M+ DG Y++E NT PGMT SL+P +A AG+ +S+L+ I+ Sbjct: 237 ACYKALKCSVYARVDMMV-KDGIPYVMEVNTLPGMTQASLLPKSADAAGIHYSKLLDMII 295 Query: 303 E 303 E Sbjct: 296 E 296 >4FU0-A nrPDB Length = 357 Score = 192 bits (489), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 120/346 (34%), Positives = 175/346 (50%), Gaps = 49/346 (14%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPV----------------------- 40 KIAV+ GG S E EVSL S +AV + D P+ Sbjct: 5 KIAVIFGGNSTEYEVSLQSASAVFENINTNKFDIIPIGITRSGEWYHYTGEKEKILNNTW 64 Query: 41 --DPKE---VDVTQLKSM-GFQK-------------VFIALHGRGGEDGTLQGMLELMGL 81 D K V V+Q +S+ GF + VF LHG+ GEDGTLQG+ EL G+ Sbjct: 65 FEDSKNLCPVVVSQNRSVKGFLEIASDKYRIIKVDLVFPVLHGKNGEDGTLQGIFELAGI 124 Query: 82 PYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPV 141 P G ++SAL MDK R+ L AG+ V V R E + + + + L P+ Sbjct: 125 PVVGCDTLSSALCMDKDRAHKLVSLAGISVPKSVTFKRFNEEAAMKEIE----ANLTYPL 180 Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI 201 +KP R GSS G++KV+ + L A+ LAF+HD EV++E+ ++G E A+LG + L Sbjct: 181 FIKPVRAGSSFGITKVIEKQELDAAIELAFEHDTEVIVEETINGFEVGCAVLGIDELIVG 240 Query: 202 R---IQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDV 258 R I+ S F+DY KY ++ + PA ++A E +Q + + LGC G+ R+D+ Sbjct: 241 RVDEIELSSGFFDYTEKYTLKSSKIYMPARIDAEAEKRIQEAAVTIYKALGCSGFSRVDM 300 Query: 259 MLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILEL 304 G+ E NT PG TSHS P + G+SFSQ++ +++ L Sbjct: 301 FYTPSGEIVFNEVNTIPGFTSHSRYPNMMKGIGLSFSQMLDKLIGL 346 >2I87-A nrPDB Length = 364 Score = 189 bits (480), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 112/341 (32%), Positives = 178/341 (52%), Gaps = 41/341 (12%) Query: 3 DKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVD----------PKEVDVT-QLK 51 + I ++ GG SAE EVS+ + VL + + D Y VD K+ ++T ++K Sbjct: 4 ENICIVFGGKSAEHEVSILTAQNVLNAIDK---DKYHVDIIYITNDGDWRKQNNITAEIK 60 Query: 52 SMG------------------------FQKVFIALHGRGGEDGTLQGMLELMGLPYTGSG 87 S + VF LHG GEDGT+QG+ E++ +PY G+G Sbjct: 61 STDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNG 120 Query: 88 VMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSR 147 V+++A SMDKL K L++ GLP P+++ R+E+EK + L PV VKP+ Sbjct: 121 VLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPAN 180 Query: 148 EGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI---RIQ 204 GSSVG+SK E L++ ++ AFQ D +++IE+ ++ E VA+LG + + + Sbjct: 181 LGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVV 240 Query: 205 PSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDG 264 FYDY++KY + Q PA L+ + L+ + L+A+ C G R D + D Sbjct: 241 KDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDN 300 Query: 265 QFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 Q Y+ E N PG T+ S+ P G+S+ +L+ +++ELA Sbjct: 301 QIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELA 341 >3I12-A nrPDB Length = 364 Score = 184 bits (468), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 101/253 (39%), Positives = 153/253 (60%), Gaps = 9/253 (3%) Query: 58 VFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVAL 117 +F +HG GEDG+LQGML + LP+ GS V++SA MDK +K L + AGL +AP++ L Sbjct: 102 IFPIVHGTLGEDGSLQGMLRVANLPFVGSDVLSSAACMDKDVAKRLLRDAGLNIAPFITL 161 Query: 118 TRAEFEKGLSDKQLAEI-SALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEE 176 TR S AE+ S LGLP+ VKP+ +GSSVG+SKV E Q A+ LAF+ D + Sbjct: 162 TRTN-RHAFS---FAEVESRLGLPLFVKPANQGSSVGVSKVANEAQYQQAVALAFEFDHK 217 Query: 177 VLIEKWLSGPEFTVAILGEEILPSI---RIQPSGTFYDYEAKYLSDE-TQYFCPAGLEAS 232 V++E+ + G E A+LG + + I + FY Y+ KY+ D Q PA + + Sbjct: 218 VVVEQGIKGREIECAVLGNDNPQASTCGEIVLNSEFYAYDTKYIDDNGAQVVVPAQIPSE 277 Query: 233 QEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGM 292 ++A+ ++A+ TLGC G R+DV L +D + + E NT PG T+ S+ P + +G+ Sbjct: 278 VNDKIRAIAIQAYQTLGCAGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQASGL 337 Query: 293 SFSQLVVRILELA 305 ++ L+ R++ELA Sbjct: 338 GYTDLISRLIELA 350 >2FB9-A nrPDB Length = 322 Score = 177 bits (450), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 123/333 (36%), Positives = 170/333 (51%), Gaps = 48/333 (14%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPK-----------EVDVTQLKS 52 ++ ++ GG S E EVSL S VL + +P D E +T L++ Sbjct: 5 RVLLIAGGVSPEHEVSLLSAEGVLRHI------PFPTDLAVIAQDGRWLLGEKALTALEA 58 Query: 53 MG----------------FQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMD 96 + VF LHGR GEDGT+QG LEL+G PY G+GV ASAL MD Sbjct: 59 KAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMD 118 Query: 97 KLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSK 156 K SK + AG+PV PWVA+ + E D VKP+ GSSVG+S+ Sbjct: 119 KDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFF----------VKPANTGSSVGISR 168 Query: 157 VVAENALQDALRLAFQHDEEVLIEKWLSG-PEFTVAILGE---EILPSIRIQPSGTFYDY 212 V L+ AL LAF++DE+ ++EK LS E V +LG E P ++ FYDY Sbjct: 169 VERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDY 228 Query: 213 EAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEAN 272 E KY + PA L+ + +Q L LKA+ LG +G R+D L ++G+ YL E N Sbjct: 229 ETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFL-AEGELYLNELN 287 Query: 273 TSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 T PG T S+ P G+++ +L+ R++ELA Sbjct: 288 TIPGFTPTSMYPRLFEAGGVAYPELLRRLVELA 320 >3E5N-A nrPDB Length = 386 Score = 167 bits (423), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 115/349 (32%), Positives = 179/349 (51%), Gaps = 50/349 (14%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREG-------GIDA--------------YPVDP 42 ++ ++ GG SAE EVSL S +L L GID + DP Sbjct: 24 RVGLIFGGKSAEHEVSLQSARNILDALDPQRFEPVLIGIDKQGQWHVNDPDSFLLHADDP 83 Query: 43 KEVDV---------------TQLKSMGFQK-------VFIALHGRGGEDGTLQGMLELMG 80 + + QL+ + ++ VF +HG GEDG+LQG+L + Sbjct: 84 ARIALHRSGRGVALLPGAQQQQLRPIQPEQALAQIDVVFPIVHGTLGEDGSLQGLLRMAN 143 Query: 81 LPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLP 140 LP+ GSGV+ SA++MDK +K + + A L VAP+V R D +A+ LGLP Sbjct: 144 LPFVGSGVLGSAVAMDKDMAKRVLRDARLAVAPFVCFDRHTAAHADVDTLIAQ---LGLP 200 Query: 141 VIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPS 200 + VKP+ +GSSVG+S+V +A AL LA +D +VL+E ++G E A+LG + + Sbjct: 201 LFVKPANQGSSVGVSQVRTADAFAAALALALAYDHKVLVEAAVAGREIECAVLGNAVPHA 260 Query: 201 I---RIQPSGTFYDYEAKYLSDE-TQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRI 256 + FY Y KY+S+ + PA ++A + +Q + ++A+ LGC G R+ Sbjct: 261 SVCGEVVVHDAFYSYATKYISEHGAEIVIPADIDAQTQQRIQQIAVQAYQALGCAGMARV 320 Query: 257 DVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 DV L +DG+ + E NT PG T S+ P + +G+ + L+ R++ELA Sbjct: 321 DVFLCADGRIVINEVNTLPGFTRISVYPKLWQASGLDYRGLITRLIELA 369 >3K3P-A nrPDB Length = 383 Score = 166 bits (421), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 113/339 (33%), Positives = 170/339 (50%), Gaps = 41/339 (12%) Query: 3 DKIAVLLGGTSAEREVSLNSGAAVLAGLREGGI----------------DAYPVDPKEVD 46 + + +L GG SAER+VS+ S +V+ + + P E D Sbjct: 38 ETLVLLYGGRSAERDVSVLSAESVMRAINYDNFLVKTYFITQAGDFIKTQEFDSQPSETD 97 Query: 47 --VTQLKSMGFQK------------VFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASA 92 +T + QK VF LHG GEDG++QG LE++ +PY G+ +++S+ Sbjct: 98 KLMTNDTIIASQKIKPSDIYEEEAVVFPVLHGPMGEDGSIQGFLEVLKMPYVGTNILSSS 157 Query: 93 LSMDKLRS-KLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEI-SALGLPVIVKPSREGS 150 ++MDK+ + ++L +P +VAL E + +LAE+ L PV VKP+ GS Sbjct: 158 VAMDKITTNQVLESATTIPQVAYVALIEGE----PLESKLAEVEEKLIYPVFVKPANMGS 213 Query: 151 SVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILG----EEILPSIRIQPS 206 SVG+SK L+ A+ LA ++D VLIE+ + E V ILG + LP I Sbjct: 214 SVGISKAENRTDLKQAIALALKYDSRVLIEQGVDAREIEVGILGNTDVKTTLPG-EIVKD 272 Query: 207 GTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQF 266 FYDYEAKY+ ++ PA ++ ++ A+ TLGC G R D L DG+ Sbjct: 273 VAFYDYEAKYIDNKITMAIPAEIDPVIVEKMRDYAATAFRTLGCCGLSRCDFFLTEDGKV 332 Query: 267 YLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 YL E NT PG T S+ P+ G+S+S L+ ++ LA Sbjct: 333 YLNELNTMPGFTQWSMYPLLWENMGLSYSVLIEELVSLA 371 >3LWB-A nrPDB Length = 373 Score = 157 bits (397), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 94/258 (36%), Positives = 140/258 (54%), Gaps = 19/258 (7%) Query: 58 VFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVAL 117 VF LHG GEDGT+QG+LEL G+PY G+GV+ASA+ MDK +K L GLPV + L Sbjct: 113 VFPVLHGPYGEDGTIQGLLELAGVPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVL 172 Query: 118 TRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEV 177 S E LGLPV VKP+R GSS+G+S+V + + L A+ A +HD +V Sbjct: 173 RPPR-----STLHRQECERLGLPVFVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKV 227 Query: 178 LIEKWLSGPEFTVAI------------LGEEILPSIRIQPSGTFYDYEAKYLSDETQYFC 225 ++E +SG E + LGE + +R + +FYD+ KYL D + Sbjct: 228 IVEAAISGRELECGVLEMPDGTLEASTLGEIRVAGVRGR-EDSFYDFATKYLDDAAELDV 286 Query: 226 PAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPM 285 PA ++ ++ L ++A+ + C+G R+D L DG + E NT PG T+ S+ P Sbjct: 287 PAKVDDQVAEAIRQLAIRAFAAIDCRGLARVDFFLTDDGPV-INEINTMPGFTTISMYPR 345 Query: 286 AARQAGMSFSQLVVRILE 303 +G+ + L+ ++E Sbjct: 346 MWAASGVDYPTLLATMIE 363 >1E4E-B nrPDB Length = 343 Score = 154 bits (388), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 108/346 (31%), Positives = 170/346 (49%), Gaps = 54/346 (15%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLA------------GLREGGI--------------DA 37 K+A+L GG S E +VS+ S + A G+ + G+ + Sbjct: 5 KVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGITKSGVWKMCEKPCAEWENENC 64 Query: 38 YPV----DPKEVDVTQLKSMGFQ-----KVFIALHGRGGEDGTLQGMLELMGLPYTGSGV 88 Y D K + K+ ++ F ALHG+ GEDG++QG+ EL G+P+ G + Sbjct: 65 YSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFVGCDI 124 Query: 89 MASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSRE 148 +SA+ MDK + ++ + AG+ + + + D+ +A + PV VKP+R Sbjct: 125 QSSAICMDKSLTYIVAKNAGIATPAFWVINK-------DDRPVA--ATFTYPVFVKPARS 175 Query: 149 GSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEI------LPSIR 202 GSS G+ KV + + L A+ A Q+D ++LIE+ +SG E A+LG + IR Sbjct: 176 GSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIR 235 Query: 203 IQPSGTFY---DYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVM 259 +Q G F + E + S+ PA L A + +Q V K + TLGC+G R+D+ Sbjct: 236 LQ-YGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETVKKIYKTLGCRGLARVDMF 294 Query: 260 LDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 L G+ L E NT PG TS+S P AG+S +L+ R++ LA Sbjct: 295 LQDRGRIVLNEVNTLPGFTSYSRYPRMMAAAGISLPELIDRLIVLA 340 >6DGI-A nrPDB Length = 337 Score = 131 bits (329), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 103/325 (31%), Positives = 147/325 (45%), Gaps = 31/325 (9%) Query: 5 IAVLLGGTSAEREVSLNSGAAVLAGLR-------------------EGGIDAYPVDPKEV 45 I +L GG S+E E+SL S + L E G Y +D Sbjct: 9 ILLLCGGGSSEHEISLVSANYIQQQLELTPEFHVIRVEMKKEGWFSEQGALVY-LDTNSA 67 Query: 46 DVTQLK-SMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLW 104 + K S V +HG GE G +Q MLEL G+PY G G ASA S +K+ SKL + Sbjct: 68 TLNSDKASYPIDFVVPCIHGFPGETGDIQSMLELAGIPYLGCGPEASANSFNKITSKLWY 127 Query: 105 QGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQ 164 +P P++ LT+ DK G + VK +R+GSSVG KV E+ + Sbjct: 128 DALDIPNTPYLFLTQN--TPSSIDKAKQAFGHWG-SIFVKAARQGSSVGCYKVTTEDQIA 184 Query: 165 DALRLAFQHDEEVLIEKWLSGPEFTVA---ILGEEIL--PSIRIQPSGTFYDYEAKYLSD 219 A+ AF E+VL+E+ + E V+ + G+ + P I P GTFY YE KY ++ Sbjct: 185 PAIEAAFGFSEQVLVEQAVKPRELEVSAYEMNGKLYISKPGEVIAPEGTFYSYEEKYSAN 244 Query: 220 ETQYFC--PAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGM 277 L + +Q + + + + RID L +GQ YL E NT PGM Sbjct: 245 SHARTVLEAENLTEKHKELIQTYAERVFIHMKLRHLSRIDFFLTQEGQIYLNEVNTFPGM 304 Query: 278 TSHSLVPMAARQAGMSFSQLVVRIL 302 T S+ P G FS+ +V+ + Sbjct: 305 TPISMFPKMLEHNGHRFSEFLVQCV 329 >1EHI-A nrPDB Length = 377 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 103/352 (29%), Positives = 164/352 (46%), Gaps = 52/352 (14%) Query: 1 MTDK-IAVLLGGTSAEREVSLNSGAAVLAGLREGG------------------------- 34 MT K +A++ GG S+E +VS S + G Sbjct: 1 MTKKRVALIFGGNSSEHDVSKRSAQNFYNAIEATGKYEIIVFAIAQNGFFLDTESSKKIL 60 Query: 35 --------IDAY--PVDPKE--VDVTQLKSMG-FQKVFIALHGRGGEDGTLQGMLELMGL 81 +DA+ VD + + LKS G F F +HG GEDGTLQG+ +L+ Sbjct: 61 ALEDEQPIVDAFMKTVDASDPLARIHALKSAGDFDIFFPVVHGNLGEDGTLQGLFKLLDK 120 Query: 82 PYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPV 141 PY G+ + A+S DK +K L G+ ++ + DK +AE LG V Sbjct: 121 PYVGAPLRGHAVSFDKALTKELLTVNGIRNTKYIVVDPESANNWSWDKIVAE---LGNIV 177 Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGP-EFTVAILGEEI--- 197 VK + +GSSVG+S+V +AL +FQ+D +VLIE+ ++G E V ++G + Sbjct: 178 FVKAANQGSSVGISRVTNAEEYTEALSDSFQYDYKVLIEEAVNGARELEVGVIGNDQPLV 237 Query: 198 ----LPSIRIQPSGT-FYDYEAKYLSDETQYF-CPAGLEASQEANLQALVLKAWTTLGCK 251 ++ Q SG +YDY K++ + +F PA L ++ + L A+ L + Sbjct: 238 SEIGAHTVPNQGSGDGWYDYNNKFVDNSAVHFQIPAQLSPEVTKEVKQMALDAYKVLNLR 297 Query: 252 GWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILE 303 G R+D +LD + YL E NT PG T+ SL + ++ ++LV +++ Sbjct: 298 GEARMDFLLDENNVPYLGEPNTLPGFTNMSLFKRLWDYSDINNAKLVDMLID 349 >3TQT-A nrPDB Length = 372 Score = 110 bits (276), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 128/253 (50%), Gaps = 8/253 (3%) Query: 58 VFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVAL 117 VF +HG GEDG LQG+LEL+ LPY G+ V +SA+ M+K +K + + G+PV W L Sbjct: 102 VFPMVHGTQGEDGALQGLLELLNLPYVGANVQSSAVCMEKDLTKTVLRAGGIPVVDWHTL 161 Query: 118 TRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEV 177 + + +G+ + L L VK GSSV V E A++ F++D+ + Sbjct: 162 SPRDATEGVYQRLLDRWGTSEL--FVKAVSLGSSVATLPVKTETEFTKAVKEVFRYDDRL 219 Query: 178 LIEKWLSGPEFTVAILG----EEILPSIRIQPSGTFYDYEAKYLS-DETQYFCPAGLEAS 232 ++E + G E A+LG + LP I P +Y Y+AKYL + L S Sbjct: 220 MVEPRIRGREIECAVLGNGAPKASLPG-EIIPHHDYYSYDAKYLDPNGATTTTSVDLSES 278 Query: 233 QEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGM 292 +Q + + A+ + C G R+D + + + + E NT PG T+ S+ P +G+ Sbjct: 279 VTKQIQQIAIDAFKMVHCSGMARVDFFVTPNNKVLVNEINTIPGFTNISMYPKMWEASGL 338 Query: 293 SFSQLVVRILELA 305 L+ +++ELA Sbjct: 339 PCPNLLDQLIELA 351 >2PVP-A nrPDB Length = 367 Score = 87.0 bits (214), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 68/225 (30%), Positives = 102/225 (45%), Gaps = 11/225 (4%) Query: 62 LHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAE 121 +HG GEDG L +LE + + G + AS LS +K +KL + G+ +V L Sbjct: 115 VHGGDGEDGKLASLLEFYRIAFIGPRIEASVLSYNKYLTKLYAKDLGIKTLDYVLLNEKN 174 Query: 122 FEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEK 181 L ++ P IVKPS GSS+G++ V E L AL AF++ +EVLIE Sbjct: 175 RANAL------DLMNFNFPFIVKPSNAGSSLGVNVVKEEKELIYALDSAFEYSKEVLIEP 228 Query: 182 WLSG-PEFTVA---ILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANL 237 ++ G E+ +A I + I F D++ KYL A L + E L Sbjct: 229 FIQGVKEYNLAGCKIKKDFCFSYIEEPNKQEFLDFKQKYLDFSRNKAPKASLSNALEEQL 288 Query: 238 QALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSL 282 + K ++ L R D + + + YL E N PG ++ L Sbjct: 289 KENFKKLYSDLFDGAIIRCDFFV-IENEVYLNEINPIPGSLANYL 332 >3VOT-A nrPDB Length = 425 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 70/244 (28%), Positives = 108/244 (44%), Gaps = 44/244 (18%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 L L GLP+T M + + +K RS L G PV EF L+D E Sbjct: 97 LNLPGLPFT---TMENCRNKNKTRSILQQNGLNTPVF-------HEFHT-LAD---LENR 142 Query: 136 ALGLPVIVKPSREGSSVGMSKVVAENALQDALRLA----------FQHDEE-VLIEKWLS 184 L P++VKP SS G+ +V L++A+R F H + ++ E+++ Sbjct: 143 KLSYPLVVKPVNGFSSQGVVRVDDRKELEEAVRKVEAVNQRDLNRFVHGKTGIVAEQFID 202 Query: 185 GPEF---TVAILGEEILPSI--RIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQA 239 GPEF T++I G + SI + G F+ +E Y PA L+ + Sbjct: 203 GPEFAIETLSIQGNVHVLSIGYKGNSKGPFF--------EEGVYIAPAQLKEETRLAIVK 254 Query: 240 LVLKAWTTLGC-KGWGRIDVMLDSDGQFYLLEANTSPGMT--SHSLVPMAARQAGMSFSQ 296 V A + LG +G ++ LD DG Y++E G + SH +V G++F Q Sbjct: 255 EVTGAVSALGIHQGPAHTELRLDKDGTPYVIEVGARIGGSGVSHYIV---KESTGINFMQ 311 Query: 297 LVVR 300 LV++ Sbjct: 312 LVLQ 315 >3OUU-A nrPDB Length = 446 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 58/214 (27%), Positives = 92/214 (42%), Gaps = 24/214 (11%) Query: 73 QGMLELM---GLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWV--ALTRAEFEKGLS 127 Q +E+ + + G V A L DK ++K + Q AG+PV P AL AE K L+ Sbjct: 93 QNFVEICAKHNIKFIGPSVEAMNLMSDKSKAKQVMQRAGVPVIPGSDGALAGAEAAKKLA 152 Query: 128 DKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH------DEEVLIEK 181 + +G PVI+K + G GM V E L+ A A D + +EK Sbjct: 153 KE-------IGYPVILKAAAGGGGRGMRVVENEKDLEKAYWSAESEAMTAFGDGTMYMEK 205 Query: 182 WLSGP-EFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGL-EASQEANLQA 239 ++ P V ++G+ I + + L +E+ PA L + L Sbjct: 206 YIQNPRHIEVQVIGDSFGNVIHVGERDCSMQRRHQKLIEES----PAILLDEKTRTRLHE 261 Query: 240 LVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 273 +KA +G +G G + ++D + FY +E NT Sbjct: 262 TAIKAAKAIGYEGAGTFEFLVDKNLDFYFIEMNT 295 >3LN7-A nrPDB Length = 757 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 21/131 (16%) Query: 81 LPYTGSGVMASALSM-------DKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAE 133 + Y +G M S S +K+ +K + Q AG V V T EK ++ L E Sbjct: 467 IEYVKNGNMTSHDSYISPLIMENKVVTKKVLQKAGFNVPQSVEFT--SLEKAVASYALFE 524 Query: 134 ISALGLPVIVKPSREGSSVGMSKVVAENALQD------ALRLAFQHDEEVLIEKWLSGPE 187 A V++KP + ++ G+ + + +Q+ AL +AF+ D+EV++E +L G E Sbjct: 525 NRA----VVIKP--KSTNYGLGITIFQQGVQNREDFAKALEIAFREDKEVMVEDYLVGTE 578 Query: 188 FTVAILGEEIL 198 + +LG+E L Sbjct: 579 YRFFVLGDETL 589 >3ORR-A nrPDB Length = 377 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 59/236 (25%), Positives = 97/236 (41%), Gaps = 33/236 (13%) Query: 72 LQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQL 131 L+ + E +P G A L D+L K + AG V P++++ + +D Sbjct: 89 LKLLCEKYNIP---QGYQAIQLLQDRLTEKETLKSAGTKVVPFISVKES------TDIDK 139 Query: 132 AEISALGLPVIVKPSREGSSVGMSKVVAENA--LQDALRLAFQHDEEVLIEKWLSGPEFT 189 A I LG P IVK +R G G +V+ N LQ+ +L E + EK+L+ Sbjct: 140 A-IETLGYPFIVK-TRFGGYDGKGQVLINNEKDLQEGFKLI--ETSECVAEKYLN----- 190 Query: 190 VAILGEEILPSIRIQPSG-TFYDYEAKYLSDETQY--FCPAGLEASQEANLQALVLKAWT 246 I E L R + TF+ + ++ + PA ++ + EA Q V K Sbjct: 191 --IKKEVSLTVTRGNNNQITFFPLQENEHRNQILFKTIVPARIDKTAEAKEQ--VNKIIQ 246 Query: 247 TLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 ++ G ++ +DS+ Q Y+ E P + H + +SQ IL Sbjct: 247 SIHFIGTFTVEFFIDSNNQLYVNEIAPRPHNSGHYSI------EACDYSQFDTHIL 296 >2C00-A nrPDB Length = 464 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 51/214 (23%), Positives = 89/214 (41%), Gaps = 17/214 (7%) Query: 68 EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLS 127 E+ +E G + G L DK+ +K + AG+P P E E Sbjct: 87 ENADFAEQIERSGFTFVGPTAEVIRLMGDKVSAKDAMKRAGVPTVPGSDGPLPEDE---- 142 Query: 128 DKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH------DEEVLIEK 181 + LA +G PVI+K + G GM V E+ L + +L + V +EK Sbjct: 143 ETALAIAREVGYPVIIKAAGGGGGRGMRVVYDESELIKSAKLTRTEAGAAFGNPMVYLEK 202 Query: 182 WLSGPEFT-VAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-GLEASQEANLQA 239 +L+ P V +L + +I + + + +E PA G++ + A Sbjct: 203 FLTNPRHVEVQVLSDGQGNAIHLGDRDCSLQRRHQKVIEEA----PAPGIDEKARQEVFA 258 Query: 240 LVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 273 ++A +G +G G + + + +G+FY +E NT Sbjct: 259 RCVQACIEIGYRGAGTFEFLYE-NGRFYFIEMNT 291 >4RZQ-A nrPDB Length = 468 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 48/216 (22%), Positives = 96/216 (44%), Gaps = 21/216 (9%) Query: 68 EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLS 127 E+ +E G + G L DK+ + + AG+P P + ++ Sbjct: 107 ENADFAEQVERSGFTFIGPTADVIRLMGDKVSAIKAMKKAGVPCVPG---SDGPVSNDIA 163 Query: 128 -DKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDAL-------RLAFQHDEEVLI 179 +K++A+ +G P+I+K S G GM V +E+AL++++ + AF +D V + Sbjct: 164 KNKEIAK--RIGYPIIIKASGGGGGRGMRVVRSEDALEESIAMTKAEAKAAFNND-MVYM 220 Query: 180 EKWLSGPEFT-VAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-GLEASQEANL 237 EK+L P + +L + ++ + + + +E PA G+ ++ Sbjct: 221 EKYLENPRHVEIQVLADTHGNAVYLAERDCSMQRRHQKVVEEA----PAPGITEEVRRDI 276 Query: 238 QALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 273 + A +G +G G + + + +G+FY +E NT Sbjct: 277 GSRCANACVEIGYRGAGTFEFLYE-NGEFYFIEMNT 311 >5KS8-A nrPDB Length = 405 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 25/45 (55%) Query: 229 LEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 273 L +Q + L +KA +G K G ++ +LDSD FY +E NT Sbjct: 179 LSKAQREYIGNLAVKAAKAVGYKNAGTVEFLLDSDNNFYFMEMNT 223 >1ULZ-A nrPDB Length = 451 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 52/219 (23%), Positives = 88/219 (40%), Gaps = 17/219 (7%) Query: 63 HGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEF 122 +G E+ M E G+ + G L DK RSK + + AG+PV P Sbjct: 81 YGFLAENAEFAKMCEEAGITFIGPHWKVIELMGDKARSKEVMKKAGVPVVPGSDGVLKSL 140 Query: 123 EKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDE------E 176 E+ K LA +G PV++K + G G+ E L A + E + Sbjct: 141 EEA---KALA--REIGYPVLLKATAGGGGRGIRICRNEEELVKNYEQASREAEKAFGRGD 195 Query: 177 VLIEKWLSGPE-FTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-GLEASQE 234 +L+EK++ P+ +LG++ I + D + + + P+ L + Sbjct: 196 LLLEKFIENPKHIEYQVLGDKHGNVIHLGER----DCSIQRRNQKLVEIAPSLILTPEKR 251 Query: 235 ANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 273 +V KA +G G ++ + D +G Y +E NT Sbjct: 252 EYYGNIVTKAAKEIGYYNAGTMEFIADQEGNLYFIEMNT 290 >2YL2-A nrPDB Length = 540 Score = 37.0 bits (84), Expect = 0.010, Method: Compositional matrix adjust. Identities = 54/238 (22%), Positives = 87/238 (36%), Gaps = 37/238 (15%) Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPW--------- 114 G E+ L +L G+ + G A DK+ S ++ Q AG+P PW Sbjct: 133 GHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDW 192 Query: 115 ---------VALTRAEFEKGL---SDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENA 162 + + + +EKG D L +G PV++K S G G+ KV N Sbjct: 193 QENDFSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKV---NN 249 Query: 163 LQDALRLAFQHDEEV------LIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKY 216 D L Q EV ++ V IL ++ +I + + Sbjct: 250 ADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQK 309 Query: 217 LSDE--TQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEAN 272 + +E PA E +++ +K +G G ++ + DG FY LE N Sbjct: 310 IIEEAPATIATPAVFE-----HMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELN 362 >2XD4-A nrPDB Length = 422 Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust. Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 25/149 (16%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 E GL G A+ + K +K L + +P A + T D+ A + Sbjct: 82 FEKAGLHVFGPSKAAAIIEGSKQFAKDLMKKYDIPTAEYETFTS-------FDEAKAYVQ 134 Query: 136 ALGLPVIVKP----SREGSSVGMSKVVAENALQDALRLAFQHDEE-------VLIEKWLS 184 G P+++K + +G +V M++ A L D F DE+ V+IE++LS Sbjct: 135 EKGAPIVIKADGLAAGKGVTVAMTEEEAIACLHD-----FLEDEKFGDASASVVIEEYLS 189 Query: 185 GPEFTVA--ILGEEILPSIRIQPSGTFYD 211 G EF++ + GE++ P + Q +D Sbjct: 190 GEEFSLMAFVKGEKVYPMVIAQDHKRAFD 218 >3U9T-A nrPDB Length = 655 Score = 36.2 bits (82), Expect = 0.020, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 85/214 (39%), Gaps = 17/214 (7%) Query: 68 EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLS 127 E+ E GL + G A K +K L + AG+P+ P + E Sbjct: 93 ENADFARACEEAGLLFLGPPAAAIDAMGSKSAAKALMEEAGVPLVPGYHGEAQDLETFRR 152 Query: 128 DKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH------DEEVLIEK 181 E +G PV++K + G GM V E L +AL A + D +L+EK Sbjct: 153 -----EAGRIGYPVLLKAAAGGGGKGMKVVEREAELAEALSSAQREAKAAFGDARMLVEK 207 Query: 182 WLSGPEFT-VAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-GLEASQEANLQA 239 +L P + + + + + + + +E PA GL A + Sbjct: 208 YLLKPRHVEIQVFADRHGHCLYLNERDCSIQRRHQKVVEEA----PAPGLGAELRRAMGE 263 Query: 240 LVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 273 ++A +G G G ++ +LD GQF+ +E NT Sbjct: 264 AAVRAAQAIGYVGAGTVEFLLDERGQFFFMEMNT 297 >3JZF-A nrPDB Length = 486 Score = 35.8 bits (81), Expect = 0.025, Method: Compositional matrix adjust. Identities = 54/226 (23%), Positives = 92/226 (40%), Gaps = 22/226 (9%) Query: 60 IALH-GRG--GEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVA 116 +A+H G G E+ +E G + G L DK+ + + AG+P P Sbjct: 97 VAIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPG-- 154 Query: 117 LTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRL------- 169 + + DK A +G PVI+K S G GM V + L ++ + Sbjct: 155 -SDGPLGDDM-DKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKA 212 Query: 170 AFQHDEEVLIEKWLSGPEFT-VAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA- 227 AF +D V +EK+L P + +L + +I + + + +E PA Sbjct: 213 AFSND-MVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAP 267 Query: 228 GLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANT 273 G+ + KA +G +G G + + + +G+FY +E NT Sbjct: 268 GITPELRRYIGERCAKACVDIGYRGAGTFEFLFE-NGEFYFIEMNT 312 >2DZD-A nrPDB Length = 461 Score = 35.0 bits (79), Expect = 0.046, Method: Compositional matrix adjust. Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 39/208 (18%) Query: 96 DKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMS 155 DK++++ AG+PV P GL D +A A G P+I+K + G GM Sbjct: 120 DKVKARHAAVNAGIPVIPGSDGP----VDGLED-VVAFAEAHGYPIIIKAALGGGGRGMR 174 Query: 156 KVVAENALQDAL-------RLAFQHDEEVLIEKWLSGPEFT-VAILGE---------EIL 198 V +++ +++A + AF D EV +EK + P+ V ILG+ E Sbjct: 175 IVRSKSEVKEAFERAKSEAKAAFGSD-EVYVEKLIENPKHIEVQILGDYEGNIVHLYERD 233 Query: 199 PSIRIQPSGTFYDYEAKYLSDE-TQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRID 257 S++ + + LSDE Q C A ++ + ++G G ++ Sbjct: 234 CSVQRRHQKVVEVAPSVSLSDELRQRICEAAVQLMR-------------SVGYVNAGTVE 280 Query: 258 VMLDSDGQFYLLEANTSPGMTSHSLVPM 285 ++ D +FY +E N H++ M Sbjct: 281 FLVSGD-EFYFIEVNPRI-QVEHTITEM 306 >3ELE-A nrPDB Length = 398 Score = 33.9 bits (76), Expect = 0.080, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 8/61 (13%) Query: 203 IQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDS 262 +P G FY + K L D++ FC ++A + +++ A GC GW RI +D Sbjct: 328 FKPDGAFYMF-VKALEDDSNAFC-------EKAKEEDVLIVAADGFGCPGWVRISYCVDR 379 Query: 263 D 263 + Sbjct: 380 E 380 >3MJF-A nrPDB Length = 431 Score = 33.9 bits (76), Expect = 0.082, Method: Compositional matrix adjust. Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 24/213 (11%) Query: 80 GLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEF------EKGLSDKQLAE 133 GL G A+ L K +K +P A + T E +KG A+ Sbjct: 91 GLAIFGPTQAAAQLEGSKAFTKDFLARHNIPSAEYQNFTDVEAALAYVRQKGAPIVIKAD 150 Query: 134 ISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPE--FTVA 191 A G VIV ++E + ++ ++A NA DA +++E++L G E F V Sbjct: 151 GLAAGKGVIVAMTQEEAETAVNDMLAGNAFGDA-------GHRIVVEEFLDGEEASFIVM 203 Query: 192 ILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTL-GC 250 + GE +LP Q D + + + PA + + + + + + W T+ G Sbjct: 204 VDGENVLPMATSQDHKRVGDGDTGPNTGGMGAYSPAPV-VTDDVHQRVMDQVIWPTVRGM 262 Query: 251 KGWGRI-------DVMLDSDGQFYLLEANTSPG 276 G I +M+ +DGQ ++E N G Sbjct: 263 AAEGNIYTGFLYAGLMISADGQPKVIEFNCRFG 295 >3LN6-A nrPDB Length = 750 Score = 33.5 bits (75), Expect = 0.11, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 3/57 (5%) Query: 140 PVIVKPSREGSSVGMS--KVVAENA-LQDALRLAFQHDEEVLIEKWLSGPEFTVAIL 193 P++VKP +G+S K A A + A+ +AF D +L+E+++ G E+ +L Sbjct: 522 PIVVKPKSTNFGLGISIFKTSANLASYEKAIDIAFTEDSAILVEEYIEGTEYRFFVL 578 >2IP4-A nrPDB Length = 417 Score = 33.1 bits (74), Expect = 0.17, Method: Compositional matrix adjust. Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 15/138 (10%) Query: 80 GLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGL 139 GL G A+ + K +K L + G+P A + F + L + LA + +G+ Sbjct: 85 GLLLFGPTQKAAMIEGSKAFAKGLMERYGIPTARYRV-----FREPL--EALAYLEEVGV 137 Query: 140 PVIVKPS----REGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAIL-- 193 PV+VK S +G +V A+ A+ + L A EV++E++L G E TV L Sbjct: 138 PVVVKDSGLAAGKGVTVAFDLHQAKQAVANILNRA--EGGEVVVEEYLEGEEATVLALTD 195 Query: 194 GEEILPSIRIQPSGTFYD 211 GE ILP + Q D Sbjct: 196 GETILPLLPSQDHKRLLD 213 >1GSO-A nrPDB Length = 431 Score = 32.3 bits (72), Expect = 0.26, Method: Compositional matrix adjust. Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 15/128 (11%) Query: 80 GLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAE------FEKGLSDKQLAE 133 GL G A+ L K +K +P A + T E EKG A+ Sbjct: 90 GLKIFGPTAGAAQLEGSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKAD 149 Query: 134 ISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPE--FTVA 191 A G VIV + E + + ++A NA DA ++IE++L G E F V Sbjct: 150 GLAAGKGVIVAMTLEEAEAAVHDMLAGNAFGDA-------GHRIVIEEFLDGEEASFIVM 202 Query: 192 ILGEEILP 199 + GE +LP Sbjct: 203 VDGEHVLP 210 >3WO0-A nrPDB Length = 470 Score = 31.6 bits (70), Expect = 0.41, Method: Compositional matrix adjust. Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 14/123 (11%) Query: 77 ELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLP-VAPWVALTRAEFEKGLSDKQLAEIS 135 E +GL G+GV A+ + DK + + + AG+ + T +F L + Sbjct: 122 ERLGL--RGAGVQAAENARDKNKMRDAFNKAGVKSIKNKRVTTLEDFRAALEE------- 172 Query: 136 ALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGE 195 +G P+I+KP+ SS+G++ + +D + + + + K ++ F + E Sbjct: 173 -IGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVT---FEAPFIAE 228 Query: 196 EIL 198 E L Sbjct: 229 EFL 231 >3AW8-A nrPDB Length = 369 Score = 31.2 bits (69), Expect = 0.52, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 10/78 (12%) Query: 93 LSMDKLRSKLLWQGAGLPVAPWVALTRAE-FEKGLSDKQLAEISALGLPVIVKPSREG-S 150 ++ D+LR K +QG G+P P+ + E E+GL +GLP ++K R G Sbjct: 93 VAQDRLREKTFFQGLGVPTPPFHPVDGPEDLEEGLKR--------VGLPALLKTRRGGYD 144 Query: 151 SVGMSKVVAENALQDALR 168 G + V E +AL+ Sbjct: 145 GKGQALVRTEEEALEALK 162 >1W93-A nrPDB Length = 553 Score = 30.8 bits (68), Expect = 0.71, Method: Compositional matrix adjust. Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 22/101 (21%) Query: 96 DKLRSKLLWQGAGLPVAPW----------------VALTRAEFEKGLS---DKQLAEISA 136 DK+ S ++ Q A +P PW V++ ++KG + L + Sbjct: 172 DKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKR 231 Query: 137 LGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEV 177 +G PV++K S G G+ +V E +D + L Q E+ Sbjct: 232 IGFPVMIKASEGGGGKGIRQVERE---EDFIALYHQAANEI 269 >3QEF-A nrPDB Length = 307 Score = 30.4 bits (67), Expect = 0.89, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Query: 238 QALVLKAWTTLGCKGWGRID--VMLDSDGQFYLLEANTSP 275 +AL+ TT W ID V +D DGQ YL NT P Sbjct: 122 KALITNDMTTDTPIDWDDIDPSVFIDDDGQAYLFWGNTRP 161 >2QK4-A nrPDB Length = 452 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 39/163 (23%), Positives = 62/163 (38%), Gaps = 16/163 (9%) Query: 74 GMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGL---SDKQ 130 G L G+ G A+ L K +K G+P A W A T+ E +D Sbjct: 106 GNLRSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIPTAQWKAFTKPEEACSFILSADFP 165 Query: 131 LAEISALGLP----VIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGP 186 + A GL VIV S+E + + +++ E A A E ++IE+ L G Sbjct: 166 ALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAA-------GETIVIEELLDGE 218 Query: 187 EFTVAIL--GEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA 227 E + G+ + P Q + + + +CPA Sbjct: 219 EVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPA 261 >4ROS-A nrPDB Length = 320 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/37 (32%), Positives = 22/37 (59%) Query: 148 EGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLS 184 +G VG+ V+ EN ++ L + F DE+ + EK ++ Sbjct: 267 DGLYVGVPVVIGENGVERVLEVTFNDDEKAMFEKSVN 303 >3TR5-A nrPDB Length = 528 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 37/96 (38%), Gaps = 21/96 (21%) Query: 15 EREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRG----GEDG 70 ++E+ +N+ +AG RE +A+P D I LH G G+ Sbjct: 336 KKEIQINNALTFMAGKRENAEEAWPGD-----------------IIGLHNHGTIQIGDTF 378 Query: 71 TLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQG 106 T + G+P S + D L+ K L +G Sbjct: 379 TQGERFKFTGIPNFASELFRLVRLKDPLKQKALLKG 414 >5UCM-A nrPDB Length = 579 Score = 27.7 bits (60), Expect = 6.9, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 8/74 (10%) Query: 86 SGVMASALSMDKLRSKLLWQGAGLPVAPW-VALTRAEFE----KGLSDKQLAEISALGLP 140 S V+A+A+ + +LW A +AP+ +AL ++E K +DK AE++A G Sbjct: 455 SRVVAAAIEQNHDERGILWPSA---LAPFQIALVPLKYETESVKQATDKLYAELTAAGFE 511 Query: 141 VIVKPSREGSSVGM 154 V++ + +S G+ Sbjct: 512 VLLDDRDKKTSPGV 525 >4WD3-A nrPDB Length = 413 Score = 27.3 bits (59), Expect = 8.1, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 7/62 (11%) Query: 85 GSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVK 144 G G + +KL K + G+PVA ++ +++ E +K LG P+IVK Sbjct: 99 GPGFETALYMTNKLAMKTKLKMEGIPVADFLCVSQVEDIPAAGEK-------LGWPIIVK 151 Query: 145 PS 146 P+ Sbjct: 152 PA 153 >5CJH-A nrPDB Length = 764 Score = 27.3 bits (59), Expect = 8.7, Method: Compositional matrix adjust. Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Query: 7 VLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRG 66 ++LGGT+A + + ++G + G +DA ++ DVTQ + Q +GRG Sbjct: 564 IVLGGTAAVEKAAKDAGVDIKVPFSAGRVDAT---QEQTDVTQFSYLEPQADGFRNYGRG 620 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4C5A-A nrPDB 452 e-128 5BPF-A nrPDB 423 e-119 4EGJ-A nrPDB 401 e-112 4EG0-A nrPDB 400 e-112 5NRH-A nrPDB 387 e-108 5D8D-A nrPDB 367 e-102 2I87-A nrPDB 366 e-102 3I12-A nrPDB 353 6e-98 3E5N-A nrPDB 344 2e-95 4FU0-A nrPDB 340 7e-94 3K3P-A nrPDB 333 4e-92 3R5X-A nrPDB 333 5e-92 2FB9-A nrPDB 329 8e-91 3LWB-A nrPDB 322 1e-88 1E4E-B nrPDB 322 1e-88 1EHI-A nrPDB 315 2e-86 6DGI-A nrPDB 311 2e-85 3TQT-A nrPDB 307 4e-84 2PVP-A nrPDB 229 8e-61 2C00-A nrPDB 179 2e-45 3OUU-A nrPDB 171 3e-43 4RZQ-A nrPDB 162 2e-40 3ORR-A nrPDB 161 3e-40 3VOT-A nrPDB 154 6e-38 3LN7-A nrPDB 97 7e-21 Sequences not found previously or not previously below threshold: 3JZF-A nrPDB 155 1e-38 1ULZ-A nrPDB 143 8e-35 2VPQ-A nrPDB 138 3e-33 3U9T-A nrPDB 138 3e-33 2DZD-A nrPDB 136 1e-32 3N6R-A nrPDB 130 1e-30 2YL2-A nrPDB 123 9e-29 5MLK-A nrPDB 104 6e-23 5H80-A nrPDB 103 8e-23 3JRW-A nrPDB 103 8e-23 1W93-A nrPDB 100 8e-22 3AX6-A nrPDB 96 2e-20 3QFF-A nrPDB 92 2e-19 5KS8-A nrPDB 84 9e-17 3WO0-A nrPDB 80 8e-16 4DIM-A nrPDB 80 1e-15 4E4T-A nrPDB 80 2e-15 3K5H-A nrPDB 76 2e-14 2Z04-A nrPDB 74 8e-14 2YW2-A nrPDB 72 3e-13 3LN6-A nrPDB 72 4e-13 2CZG-A nrPDB 72 4e-13 3AW8-A nrPDB 72 4e-13 1EZ1-A nrPDB 71 7e-13 4IZO-A nrPDB 70 1e-12 2IP4-A nrPDB 69 3e-12 4IWX-A nrPDB 67 7e-12 2XD4-A nrPDB 67 1e-11 2PN1-A nrPDB 67 1e-11 3VPD-A nrPDB 67 1e-11 4WD3-A nrPDB 65 4e-11 1GSO-A nrPDB 61 6e-10 5VEV-A nrPDB 61 7e-10 3ETH-A nrPDB 60 1e-09 3MJF-A nrPDB 59 2e-09 2YS6-A nrPDB 58 7e-09 1UC8-A nrPDB 57 9e-09 3VPB-A nrPDB 57 1e-08 5K2M-A nrPDB 56 2e-08 3LP8-A nrPDB 55 4e-08 2CQY-A nrPDB 54 6e-08 5I47-A nrPDB 48 4e-06 1PK8-A nrPDB 42 4e-04 2R84-A nrPDB 40 0.002 4FFM-A nrPDB 40 0.002 1AUX-A nrPDB 39 0.003 3WVR-A nrPDB 38 0.003 1I7L-A nrPDB 36 0.027 3GG2-A nrPDB 35 0.052 1QWG-A nrPDB 33 0.15 3TIN-A nrPDB 32 0.30 6HQJ-A nrPDB 32 0.40 5CA0-F nrPDB 32 0.47 4ROS-A nrPDB 32 0.48 3UFX-B nrPDB 31 0.61 3E96-A nrPDB 31 0.61 3MMZ-A nrPDB 31 0.69 5JRY-A nrPDB 30 1.0 6GVJ-A nrPDB 30 1.3 3HMP-A nrPDB 30 1.3 2ZMD-A nrPDB 30 1.3 4M88-A nrPDB 30 1.5 4OB3-A nrPDB 30 1.5 4OB1-A nrPDB 30 1.5 5AP3-A nrPDB 30 1.7 5J6B-A nrPDB 30 1.9 1WR2-A nrPDB 29 2.0 4JHH-A nrPDB 28 3.4 3EYA-A nrPDB 28 3.5 3Q94-A nrPDB 28 4.3 3H9U-A nrPDB 27 8.2 >4C5A-A nrPDB Length = 330 Score = 452 bits (1163), Expect = e-128, Method: Composition-based stats. Identities = 306/306 (100%), Positives = 306/306 (100%) Query: 1 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI 60 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI Sbjct: 25 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI 84 Query: 61 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA 120 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA Sbjct: 85 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA 144 Query: 121 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE 180 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE Sbjct: 145 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE 204 Query: 181 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL 240 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL Sbjct: 205 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL 264 Query: 241 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR 300 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR Sbjct: 265 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR 324 Query: 301 ILELAD 306 ILELAD Sbjct: 325 ILELAD 330 >5BPF-A nrPDB Length = 306 Score = 423 bits (1088), Expect = e-119, Method: Composition-based stats. Identities = 222/306 (72%), Positives = 252/306 (82%) Query: 1 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFI 60 M +K+AVLLGGTSAEREVSL SG AVLAGL+E GIDAY VD K+ VTQLK GF KVFI Sbjct: 1 MAEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFI 60 Query: 61 ALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRA 120 ALHGRGGEDGTLQG+LE + LPYTGSGVMASAL+MDKLR+KL+WQ GLP++P+VAL R Sbjct: 61 ALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQ 120 Query: 121 EFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE 180 +FE ++ +A ++ LGLP+IVKPS EGSSVGMSKV + LQ AL AFQHD +VLIE Sbjct: 121 QFETLSPEELVACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKALVEAFQHDSDVLIE 180 Query: 181 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL 240 KWLSGPEFTVAILG+E+LPSIRIQP G FYDY+AKYLSD+TQYFCP+GL E L AL Sbjct: 181 KWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAAL 240 Query: 241 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVR 300 L+A+ L C GWGR+DVM D DG FYLLE NTSPGMTSHSLVPMAARQ G+SFSQLV R Sbjct: 241 ALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVAR 300 Query: 301 ILELAD 306 IL LAD Sbjct: 301 ILMLAD 306 >4EGJ-A nrPDB Length = 334 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 158/302 (52%), Positives = 204/302 (67%), Gaps = 4/302 (1%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVLLGG SAEREVSLNSG VL GLR+ GIDA+P DP E + LK GF + F ALH Sbjct: 32 KVAVLLGGNSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAERPLAALKEEGFVRAFNALH 91 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 G GE+G +QG L+ G+ YTGSGV+ SAL +DK R+KL+WQ G+P P+ A+ R + Sbjct: 92 GGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQLGIPTPPFEAVLRGDDY 151 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 + + + +A LGLP+ VKP+ EGSSV + KV + +AL AL A + D V++EK + Sbjct: 152 EARAKEIVA---KLGLPLFVKPASEGSSVAVIKVKSADALPAALIEAVKFDRIVVVEKSI 208 Query: 184 S-GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 G E+T I G LP IRI P+G FYDY AKY++++TQY P GL A +EA L+ L Sbjct: 209 EGGGEYTACIAGNLDLPVIRIVPAGEFYDYHAKYIANDTQYLIPCGLTADEEARLKVLAR 268 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 +A+ LGC WGR D MLD+DG Y LE NT+PGMT HSL P AAR G+S+ +LVV +L Sbjct: 269 RAFDVLGCTDWGRADFMLDADGNPYFLEVNTAPGMTDHSLPPKAARAVGISYQELVVAVL 328 Query: 303 EL 304 L Sbjct: 329 AL 330 >4EG0-A nrPDB Length = 317 Score = 400 bits (1028), Expect = e-112, Method: Composition-based stats. Identities = 153/302 (50%), Positives = 200/302 (66%), Gaps = 4/302 (1%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVL GG SAEREVSL SG VL GLR+ GIDA+P DP E ++ LK GF + F ALH Sbjct: 15 KVAVLFGGESAEREVSLTSGRLVLQGLRDAGIDAHPFDPAERPLSALKDEGFVRAFNALH 74 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 G GE+G +QG L+ G+ YTGSGV+ SAL +DK R+KL+WQ G+P P+ + R + Sbjct: 75 GGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGVPTPPFETVMRGDDY 134 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 + +A LGLP+ VKP+ EGSSV + KV +AL AL A HD+ V++EK + Sbjct: 135 AARATDIVA---KLGLPLFVKPASEGSSVAVLKVKTADALPAALSEAATHDKIVIVEKSI 191 Query: 184 S-GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 G E+T I G+ LP I+I P+G FYDY AKY++++TQY P GL A QE L+ + Sbjct: 192 EGGGEYTACIAGDLDLPLIKIVPAGEFYDYHAKYVANDTQYLIPCGLPAEQETELKRIAR 251 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 +A+ LGC WGR D MLD+ G Y LE NT+PGMT HSL P AAR G+ +S+LVV++L Sbjct: 252 RAFDVLGCTDWGRADFMLDAAGNAYFLEVNTAPGMTDHSLPPKAARSIGIGYSELVVKVL 311 Query: 303 EL 304 L Sbjct: 312 SL 313 >5NRH-A nrPDB Length = 312 Score = 387 bits (994), Expect = e-108, Method: Composition-based stats. Identities = 152/302 (50%), Positives = 204/302 (67%), Gaps = 4/302 (1%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVLLGG SAEREVSLNSG VL GLR+ GIDA+P DP + + LK GF + F ALH Sbjct: 11 KVAVLLGGDSAEREVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALH 70 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 G GE+G +QG L+ G+ YTGSGV+ SAL +DK R+KL+WQ G+P P+ + R + Sbjct: 71 GGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDY 130 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 + +A LG+P+ VKP+ EGSSV + KV + +AL AL A +HD+ V++EK + Sbjct: 131 AARAQDIVA---KLGVPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSI 187 Query: 184 S-GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 G E+T I + LP IRI P+G FYDY AKY++++TQY P GL+A++EA + + Sbjct: 188 EGGGEYTACIAADLDLPLIRIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIAR 247 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 +A+ LGC WGR D MLD+ G Y LE NT+PGMT HSL P AAR G+ +S+LVV++L Sbjct: 248 RAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGIGYSELVVKVL 307 Query: 303 EL 304 L Sbjct: 308 SL 309 >5D8D-A nrPDB Length = 308 Score = 367 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 158/302 (52%), Positives = 203/302 (67%), Gaps = 11/302 (3%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 K+AVLLGG SAER VSL+SG AVL L G+ A DP++ VT+L + + + FI LH Sbjct: 9 KVAVLLGGKSAERAVSLDSGQAVLDALLRSGVQAEAFDPQDRSVTEL--VNYDRAFIVLH 66 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 GRGGEDG +QG+LE + +PYTG+GV SA+ MDK+++K +WQG+ LP AP+ +T+ Sbjct: 67 GRGGEDGQIQGVLEWLNIPYTGTGVQGSAIGMDKVKTKQIWQGSDLPTAPYRIITKETD- 125 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 D +AE LGLPVI+KP EGSSVGMSKV A+ A QHD V+ EKW+ Sbjct: 126 ---LDSVIAE---LGLPVIIKPVHEGSSVGMSKVEKAEDFAAAIEKATQHDAVVMAEKWI 179 Query: 184 SGPEFTVAILGEEILPSIRIQPSGT--FYDYEAKYLSDETQYFCPAGLEASQEANLQALV 241 +G EFT++ L + LP IR+QP FYDYEAKY ++ +Y P GL ++E LQAL Sbjct: 180 TGREFTISFLNGQPLPVIRLQPPADVAFYDYEAKYQRNDVEYGIPCGLSETEEKKLQALC 239 Query: 242 LKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRI 301 L+A+ +G +GWGRID M D G F+LLE NT PGMTSHSLVP AA+ G SF +L V I Sbjct: 240 LRAFQAVGAEGWGRIDAMQDEQGNFWLLEVNTVPGMTSHSLVPKAAKAVGYSFDELCVAI 299 Query: 302 LE 303 LE Sbjct: 300 LE 301 >2I87-A nrPDB Length = 364 Score = 366 bits (940), Expect = e-102, Method: Composition-based stats. Identities = 112/341 (32%), Positives = 178/341 (52%), Gaps = 41/341 (12%) Query: 3 DKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVD----------PKEVDVT-QLK 51 + I ++ GG SAE EVS+ + VL + + D Y VD K+ ++T ++K Sbjct: 4 ENICIVFGGKSAEHEVSILTAQNVLNAIDK---DKYHVDIIYITNDGDWRKQNNITAEIK 60 Query: 52 S------------------------MGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSG 87 S + VF LHG GEDGT+QG+ E++ +PY G+G Sbjct: 61 STDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNG 120 Query: 88 VMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSR 147 V+++A SMDKL K L++ GLP P+++ R+E+EK + L PV VKP+ Sbjct: 121 VLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPAN 180 Query: 148 EGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI---RIQ 204 GSSVG+SK E L++ ++ AFQ D +++IE+ ++ E VA+LG + + + Sbjct: 181 LGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVV 240 Query: 205 PSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDG 264 FYDY++KY + Q PA L+ + L+ + L+A+ C G R D + D Sbjct: 241 KDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDN 300 Query: 265 QFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 Q Y+ E N PG T+ S+ P G+S+ +L+ +++ELA Sbjct: 301 QIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELA 341 >3I12-A nrPDB Length = 364 Score = 353 bits (905), Expect = 6e-98, Method: Composition-based stats. Identities = 112/349 (32%), Positives = 176/349 (50%), Gaps = 50/349 (14%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAY---------------------PVDP 42 ++ ++ GG SAE EVSL S ++ + + D DP Sbjct: 5 RVGIVFGGKSAEHEVSLQSAKNIVDAIDKTRFDVVLLGIDKAGQWHVNDAENYLQNADDP 64 Query: 43 KEVDV---------------TQLKSMG-------FQKVFIALHGRGGEDGTLQGMLELMG 80 + + QL + +F +HG GEDG+LQGML + Sbjct: 65 AHIALRPSAISLAQVPGKHQHQLINAQNGQPLPTVDVIFPIVHGTLGEDGSLQGMLRVAN 124 Query: 81 LPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLP 140 LP+ GS V++SA MDK +K L + AGL +AP++ LTR + S LGLP Sbjct: 125 LPFVGSDVLSSAACMDKDVAKRLLRDAGLNIAPFITLTRTNRHAFSFAEV---ESRLGLP 181 Query: 141 VIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPS 200 + VKP+ +GSSVG+SKV E Q A+ LAF+ D +V++E+ + G E A+LG + + Sbjct: 182 LFVKPANQGSSVGVSKVANEAQYQQAVALAFEFDHKVVVEQGIKGREIECAVLGNDNPQA 241 Query: 201 ---IRIQPSGTFYDYEAKYLS-DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRI 256 I + FY Y+ KY+ + Q PA + + ++A+ ++A+ TLGC G R+ Sbjct: 242 STCGEIVLNSEFYAYDTKYIDDNGAQVVVPAQIPSEVNDKIRAIAIQAYQTLGCAGMARV 301 Query: 257 DVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 DV L +D + + E NT PG T+ S+ P + +G+ ++ L+ R++ELA Sbjct: 302 DVFLTADNEVVINEINTLPGFTNISMYPKLWQASGLGYTDLISRLIELA 350 >3E5N-A nrPDB Length = 386 Score = 344 bits (883), Expect = 2e-95, Method: Composition-based stats. Identities = 112/349 (32%), Positives = 175/349 (50%), Gaps = 50/349 (14%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDA---------------------YPVDP 42 ++ ++ GG SAE EVSL S +L L + + DP Sbjct: 24 RVGLIFGGKSAEHEVSLQSARNILDALDPQRFEPVLIGIDKQGQWHVNDPDSFLLHADDP 83 Query: 43 KEVDVT---------------QLKSMG-------FQKVFIALHGRGGEDGTLQGMLELMG 80 + + QL+ + VF +HG GEDG+LQG+L + Sbjct: 84 ARIALHRSGRGVALLPGAQQQQLRPIQPEQALAQIDVVFPIVHGTLGEDGSLQGLLRMAN 143 Query: 81 LPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLP 140 LP+ GSGV+ SA++MDK +K + + A L VAP+V R D +A+ LGLP Sbjct: 144 LPFVGSGVLGSAVAMDKDMAKRVLRDARLAVAPFVCFDRHTAAHADVDTLIAQ---LGLP 200 Query: 141 VIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPS 200 + VKP+ +GSSVG+S+V +A AL LA +D +VL+E ++G E A+LG + + Sbjct: 201 LFVKPANQGSSVGVSQVRTADAFAAALALALAYDHKVLVEAAVAGREIECAVLGNAVPHA 260 Query: 201 ---IRIQPSGTFYDYEAKYLSDE-TQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRI 256 + FY Y KY+S+ + PA ++A + +Q + ++A+ LGC G R+ Sbjct: 261 SVCGEVVVHDAFYSYATKYISEHGAEIVIPADIDAQTQQRIQQIAVQAYQALGCAGMARV 320 Query: 257 DVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 DV L +DG+ + E NT PG T S+ P + +G+ + L+ R++ELA Sbjct: 321 DVFLCADGRIVINEVNTLPGFTRISVYPKLWQASGLDYRGLITRLIELA 369 >4FU0-A nrPDB Length = 357 Score = 340 bits (871), Expect = 7e-94, Method: Composition-based stats. Identities = 118/347 (34%), Positives = 172/347 (49%), Gaps = 49/347 (14%) Query: 3 DKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPV---------------------- 40 KIAV+ GG S E EVSL S +AV + D P+ Sbjct: 4 KKIAVIFGGNSTEYEVSLQSASAVFENINTNKFDIIPIGITRSGEWYHYTGEKEKILNNT 63 Query: 41 ---DPKE---VDVTQLKS--------------MGFQKVFIALHGRGGEDGTLQGMLELMG 80 D K V V+Q +S + VF LHG+ GEDGTLQG+ EL G Sbjct: 64 WFEDSKNLCPVVVSQNRSVKGFLEIASDKYRIIKVDLVFPVLHGKNGEDGTLQGIFELAG 123 Query: 81 LPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLP 140 +P G ++SAL MDK R+ L AG+ V V R E + + + + L P Sbjct: 124 IPVVGCDTLSSALCMDKDRAHKLVSLAGISVPKSVTFKRFNEEAAMKEIE----ANLTYP 179 Query: 141 VIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPS 200 + +KP R GSS G++KV+ + L A+ LAF+HD EV++E+ ++G E A+LG + L Sbjct: 180 LFIKPVRAGSSFGITKVIEKQELDAAIELAFEHDTEVIVEETINGFEVGCAVLGIDELIV 239 Query: 201 IR---IQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRID 257 R I+ S F+DY KY ++ + PA ++A E +Q + + LGC G+ R+D Sbjct: 240 GRVDEIELSSGFFDYTEKYTLKSSKIYMPARIDAEAEKRIQEAAVTIYKALGCSGFSRVD 299 Query: 258 VMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILEL 304 + G+ E NT PG TSHS P + G+SFSQ++ +++ L Sbjct: 300 MFYTPSGEIVFNEVNTIPGFTSHSRYPNMMKGIGLSFSQMLDKLIGL 346 >3K3P-A nrPDB Length = 383 Score = 333 bits (855), Expect = 4e-92, Method: Composition-based stats. Identities = 109/338 (32%), Positives = 166/338 (49%), Gaps = 39/338 (11%) Query: 3 DKIAVLLGGTSAEREVSLNSGAAVLAGLREGGI----------------DAYPVDPKEVD 46 + + +L GG SAER+VS+ S +V+ + + P E D Sbjct: 38 ETLVLLYGGRSAERDVSVLSAESVMRAINYDNFLVKTYFITQAGDFIKTQEFDSQPSETD 97 Query: 47 --------VTQLKSMGFQ------KVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASA 92 + K VF LHG GEDG++QG LE++ +PY G+ +++S+ Sbjct: 98 KLMTNDTIIASQKIKPSDIYEEEAVVFPVLHGPMGEDGSIQGFLEVLKMPYVGTNILSSS 157 Query: 93 LSMDKLRSKLLWQGAG-LPVAPWVALTRAEFEKGLSDKQLAEIS-ALGLPVIVKPSREGS 150 ++MDK+ + + + A +P +VAL E + +LAE+ L PV VKP+ GS Sbjct: 158 VAMDKITTNQVLESATTIPQVAYVALIEGE----PLESKLAEVEEKLIYPVFVKPANMGS 213 Query: 151 SVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI---RIQPSG 207 SVG+SK L+ A+ LA ++D VLIE+ + E V ILG + + I Sbjct: 214 SVGISKAENRTDLKQAIALALKYDSRVLIEQGVDAREIEVGILGNTDVKTTLPGEIVKDV 273 Query: 208 TFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFY 267 FYDYEAKY+ ++ PA ++ ++ A+ TLGC G R D L DG+ Y Sbjct: 274 AFYDYEAKYIDNKITMAIPAEIDPVIVEKMRDYAATAFRTLGCCGLSRCDFFLTEDGKVY 333 Query: 268 LLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 L E NT PG T S+ P+ G+S+S L+ ++ LA Sbjct: 334 LNELNTMPGFTQWSMYPLLWENMGLSYSVLIEELVSLA 371 >3R5X-A nrPDB Length = 307 Score = 333 bits (854), Expect = 5e-92, Method: Composition-based stats. Identities = 109/300 (36%), Positives = 171/300 (57%), Gaps = 8/300 (2%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALH 63 +I V++GG S+E++VS+ +G ++A L + + P+ E K+ +ALH Sbjct: 5 RIGVIMGGVSSEKQVSIMTGNEMIANLDKNKYEIVPITLNEKMDLIEKAKDIDFALLALH 64 Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFE 123 G+ GEDGT+QG LE +G+PY+GS +++S + MDK SK + + G+ W+ LT+ E Sbjct: 65 GKYGEDGTVQGTLESLGIPYSGSNMLSSGICMDKNISKKILRYEGIETPDWIELTKME-- 122 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL 183 D E+ LG P++VKP+ GSSVG+ V ++ L L F+ D EV+IEK++ Sbjct: 123 ----DLNFDELDKLGFPLVVKPNSGGSSVGVKIVYDKDELISMLETVFEWDSEVVIEKYI 178 Query: 184 SGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLK 243 G E T +I + LP I I+ + F+DY AKY D + L A + + L Sbjct: 179 KGEEITCSIFDGKQLPIISIRHAAEFFDYNAKY-DDASTIEEVIELPAELKERVNKASLA 237 Query: 244 AWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILE 303 + L C + R+D+M+ DG Y++E NT PGMT SL+P +A AG+ +S+L+ I+E Sbjct: 238 CYKALKCSVYARVDMMV-KDGIPYVMEVNTLPGMTQASLLPKSADAAGIHYSKLLDMIIE 296 >2FB9-A nrPDB Length = 322 Score = 329 bits (844), Expect = 8e-91, Method: Composition-based stats. Identities = 121/333 (36%), Positives = 168/333 (50%), Gaps = 48/333 (14%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPK-----------EVDVTQLKS 52 ++ ++ GG S E EVSL S VL + +P D E +T L++ Sbjct: 5 RVLLIAGGVSPEHEVSLLSAEGVLRHI------PFPTDLAVIAQDGRWLLGEKALTALEA 58 Query: 53 MG----------------FQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMD 96 + VF LHGR GEDGT+QG LEL+G PY G+GV ASAL MD Sbjct: 59 KAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMD 118 Query: 97 KLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSK 156 K SK + AG+PV PWVA+ + E D KP+ GSSVG+S+ Sbjct: 119 KDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFV----------KPANTGSSVGISR 168 Query: 157 VVAENALQDALRLAFQHDEEVLIEKWLSG-PEFTVAILGEEIL---PSIRIQPSGTFYDY 212 V L+ AL LAF++DE+ ++EK LS E V +LG P ++ FYDY Sbjct: 169 VERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDY 228 Query: 213 EAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEAN 272 E KY + PA L+ + +Q L LKA+ LG +G R+D L ++G+ YL E N Sbjct: 229 ETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFL-AEGELYLNELN 287 Query: 273 TSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 T PG T S+ P G+++ +L+ R++ELA Sbjct: 288 TIPGFTPTSMYPRLFEAGGVAYPELLRRLVELA 320 >3LWB-A nrPDB Length = 373 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 107/354 (30%), Positives = 159/354 (44%), Gaps = 66/354 (18%) Query: 9 LGGTSAEREVSLNSGAAVLAGLREGGIDAYPV-----------DPK-------EVDVTQL 50 GG S E +S S ++L L D V D ++ Q+ Sbjct: 17 FGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQV 76 Query: 51 KS-----------------------------MGFQKVFIALHGRGGEDGTLQGMLELMGL 81 KS VF LHG GEDGT+QG+LEL G+ Sbjct: 77 KSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAGV 136 Query: 82 PYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPV 141 PY G+GV+ASA+ MDK +K L GLPV + L E LGLPV Sbjct: 137 PYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRST-----LHRQECERLGLPV 191 Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAI--------- 192 VKP+R GSS+G+S+V + + L A+ A +HD +V++E +SG E + Sbjct: 192 FVKPARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLE 251 Query: 193 ---LGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLG 249 LGE + +R + +FYD+ KYL D + PA ++ ++ L ++A+ + Sbjct: 252 ASTLGEIRVAGVRGR-EDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAID 310 Query: 250 CKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILE 303 C+G R+D L DG + E NT PG T+ S+ P +G+ + L+ ++E Sbjct: 311 CRGLARVDFFLTDDG-PVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIE 363 >1E4E-B nrPDB Length = 343 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 103/346 (29%), Positives = 163/346 (47%), Gaps = 54/346 (15%) Query: 4 KIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPV----------------------- 40 K+A+L GG S E +VS+ S + A + + + + Sbjct: 5 KVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGITKSGVWKMCEKPCAEWENENC 64 Query: 41 -------DPKEVDVTQLKSMGF-----QKVFIALHGRGGEDGTLQGMLELMGLPYTGSGV 88 D K + K+ + F ALHG+ GEDG++QG+ EL G+P+ G + Sbjct: 65 YSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFVGCDI 124 Query: 89 MASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSRE 148 +SA+ MDK + ++ + AG+ + + + + + PV VKP+R Sbjct: 125 QSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVA---------ATFTYPVFVKPARS 175 Query: 149 GSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEE------ILPSIR 202 GSS G+ KV + + L A+ A Q+D ++LIE+ +SG E A+LG + IR Sbjct: 176 GSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIR 235 Query: 203 IQPSGTFY---DYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVM 259 +Q G F + E + S+ PA L A + +Q V K + TLGC+G R+D+ Sbjct: 236 LQ-YGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETVKKIYKTLGCRGLARVDMF 294 Query: 260 LDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 L G+ L E NT PG TS+S P AG+S +L+ R++ LA Sbjct: 295 LQDRGRIVLNEVNTLPGFTSYSRYPRMMAAAGISLPELIDRLIVLA 340 >1EHI-A nrPDB Length = 377 Score = 315 bits (806), Expect = 2e-86, Method: Composition-based stats. Identities = 98/349 (28%), Positives = 158/349 (45%), Gaps = 51/349 (14%) Query: 3 DKIAVLLGGTSAEREVSLNSGAAVLAGLREGG---------------------------- 34 ++A++ GG S+E +VS S + G Sbjct: 4 KRVALIFGGNSSEHDVSKRSAQNFYNAIEATGKYEIIVFAIAQNGFFLDTESSKKILALE 63 Query: 35 -----IDAY--PVDPKE--VDVTQLKSMG-FQKVFIALHGRGGEDGTLQGMLELMGLPYT 84 +DA+ VD + + LKS G F F +HG GEDGTLQG+ +L+ PY Sbjct: 64 DEQPIVDAFMKTVDASDPLARIHALKSAGDFDIFFPVVHGNLGEDGTLQGLFKLLDKPYV 123 Query: 85 GSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVK 144 G+ + A+S DK +K L G+ ++ + DK +AE LG V VK Sbjct: 124 GAPLRGHAVSFDKALTKELLTVNGIRNTKYIVVDPESANNWSWDKIVAE---LGNIVFVK 180 Query: 145 PSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSG-PEFTVAILGEEILPSIRI 203 + +GSSVG+S+V +AL +FQ+D +VLIE+ ++G E V ++G + I Sbjct: 181 AANQGSSVGISRVTNAEEYTEALSDSFQYDYKVLIEEAVNGARELEVGVIGNDQPLVSEI 240 Query: 204 QPS--------GTFYDYEAKYLSDETQYF-CPAGLEASQEANLQALVLKAWTTLGCKGWG 254 +YDY K++ + +F PA L ++ + L A+ L +G Sbjct: 241 GAHTVPNQGSGDGWYDYNNKFVDNSAVHFQIPAQLSPEVTKEVKQMALDAYKVLNLRGEA 300 Query: 255 RIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILE 303 R+D +LD + YL E NT PG T+ SL + ++ ++LV +++ Sbjct: 301 RMDFLLDENNVPYLGEPNTLPGFTNMSLFKRLWDYSDINNAKLVDMLID 349 >6DGI-A nrPDB Length = 337 Score = 311 bits (797), Expect = 2e-85, Method: Composition-based stats. Identities = 105/330 (31%), Positives = 149/330 (45%), Gaps = 32/330 (9%) Query: 1 MTDK-IAVLLGGTSAEREVSLNSGAAVLAGLR-------------------EGGIDAYPV 40 MT I +L GG S+E E+SL S + L E G Y + Sbjct: 4 MTKTTILLLCGGGSSEHEISLVSANYIQQQLELTPEFHVIRVEMKKEGWFSEQGALVY-L 62 Query: 41 DPKEVDVTQLK-SMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLR 99 D + K S V +HG GE G +Q MLEL G+PY G G ASA S +K+ Sbjct: 63 DTNSATLNSDKASYPIDFVVPCIHGFPGETGDIQSMLELAGIPYLGCGPEASANSFNKIT 122 Query: 100 SKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVA 159 SKL + +P P++ LT+ DK G + VK +R+GSSVG KV Sbjct: 123 SKLWYDALDIPNTPYLFLTQN--TPSSIDKAKQAFGHWG-SIFVKAARQGSSVGCYKVTT 179 Query: 160 ENALQDALRLAFQHDEEVLIEKWLSGPEFTVA---ILGEEIL--PSIRIQPSGTFYDYEA 214 E+ + A+ AF E+VL+E+ + E V+ + G+ + P I P GTFY YE Sbjct: 180 EDQIAPAIEAAFGFSEQVLVEQAVKPRELEVSAYEMNGKLYISKPGEVIAPEGTFYSYEE 239 Query: 215 KYLSDETQYFC--PAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEAN 272 KY ++ L + +Q + + + + RID L +GQ YL E N Sbjct: 240 KYSANSHARTVLEAENLTEKHKELIQTYAERVFIHMKLRHLSRIDFFLTQEGQIYLNEVN 299 Query: 273 TSPGMTSHSLVPMAARQAGMSFSQLVVRIL 302 T PGMT S+ P G FS+ +V+ + Sbjct: 300 TFPGMTPISMFPKMLEHNGHRFSEFLVQCV 329 >3TQT-A nrPDB Length = 372 Score = 307 bits (786), Expect = 4e-84, Method: Composition-based stats. Identities = 93/353 (26%), Positives = 152/353 (43%), Gaps = 50/353 (14%) Query: 1 MTDK--IAVLLGGTSAEREVSLNSGAAVLAGLREGGIDA-----------YPVDPKEVDV 47 M +K I+VL GG S E E+S+ S ++ L Y +D E+ + Sbjct: 1 MAEKLHISVLCGGQSTEHEISIQSAKNIVNTLDAAKYLISVIFIDHVGRWYLIDQPEMFL 60 Query: 48 TQL-------------------------------KSMGFQKVFIALHGRGGEDGTLQGML 76 + VF +HG GEDG LQG+L Sbjct: 61 AHSPDHLVKEGSARPITIAFGDAAKPWQSLNGDGRRYSADCVFPMVHGTQGEDGALQGLL 120 Query: 77 ELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISA 136 EL+ LPY G+ V +SA+ M+K +K + + G+PV W L+ + +G+ + L Sbjct: 121 ELLNLPYVGANVQSSAVCMEKDLTKTVLRAGGIPVVDWHTLSPRDATEGVYQRLLDRWGT 180 Query: 137 LGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEE 196 + VK GSSV V E A++ F++D+ +++E + G E A+LG Sbjct: 181 SE--LFVKAVSLGSSVATLPVKTETEFTKAVKEVFRYDDRLMVEPRIRGREIECAVLGNG 238 Query: 197 ILPS---IRIQPSGTFYDYEAKYLS-DETQYFCPAGLEASQEANLQALVLKAWTTLGCKG 252 + I P +Y Y+AKYL + L S +Q + + A+ + C G Sbjct: 239 APKASLPGEIIPHHDYYSYDAKYLDPNGATTTTSVDLSESVTKQIQQIAIDAFKMVHCSG 298 Query: 253 WGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 R+D + + + + E NT PG T+ S+ P +G+ L+ +++ELA Sbjct: 299 MARVDFFVTPNNKVLVNEINTIPGFTNISMYPKMWEASGLPCPNLLDQLIELA 351 >2PVP-A nrPDB Length = 367 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 84/317 (26%), Positives = 124/317 (39%), Gaps = 46/317 (14%) Query: 6 AVLLGGTSAEREVSLNSGAAVLAGLRE--------------------GGIDAYPVDPKEV 45 VL GG S E E+S+ S A+ L++ Y KE Sbjct: 24 CVLFGGASFEHEISIVSAIALKGVLKDRIKYFIFLDENHHFYLIEESNMHSKYFAQIKEK 83 Query: 46 DVTQL---------------KSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMA 90 + L K + V +HG GEDG L +LE + + G + A Sbjct: 84 KLPPLILTHNGLLKNSFLGAKIIELPLVINLVHGGDGEDGKLASLLEFYRIAFIGPRIEA 143 Query: 91 SALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGS 150 S LS +K +KL + G+ +V L L ++ P IVKPS GS Sbjct: 144 SVLSYNKYLTKLYAKDLGIKTLDYVLLNEKNRANAL------DLMNFNFPFIVKPSNAGS 197 Query: 151 SVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSG-PEFT---VAILGEEILPSIRIQPS 206 S+G++ V E L AL AF++ +EVLIE ++ G E+ I + I Sbjct: 198 SLGVNVVKEEKELIYALDSAFEYSKEVLIEPFIQGVKEYNLAGCKIKKDFCFSYIEEPNK 257 Query: 207 GTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQF 266 F D++ KYL A L + E L+ K ++ L R D + + + Sbjct: 258 QEFLDFKQKYLDFSRNKAPKASLSNALEEQLKENFKKLYSDLFDGAIIRCDFFV-IENEV 316 Query: 267 YLLEANTSPGMTSHSLV 283 YL E N PG ++ L Sbjct: 317 YLNEINPIPGSLANYLF 333 >2C00-A nrPDB Length = 464 Score = 179 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 20/225 (8%) Query: 61 ALHGRGG---EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVAL 117 A+H G E+ +E G + G L DK+ +K + AG+P P Sbjct: 77 AIHPGYGFLAENADFAEQIERSGFTFVGPTAEVIRLMGDKVSAKDAMKRAGVPTVPGSDG 136 Query: 118 TRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH---- 173 E E + LA +G PVI+K + G GM V E+ L + +L Sbjct: 137 PLPEDE----ETALAIAREVGYPVIIKAAGGGGGRGMRVVYDESELIKSAKLTRTEAGAA 192 Query: 174 --DEEVLIEKWLSGPEF-TVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-GL 229 + V +EK+L+ P V +L + +I + + + +E PA G+ Sbjct: 193 FGNPMVYLEKFLTNPRHVEVQVLSDGQGNAIHLGDRDCSLQRRHQKVIEEA----PAPGI 248 Query: 230 EASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 + + A ++A +G +G G + + +G+FY +E NT Sbjct: 249 DEKARQEVFARCVQACIEIGYRGAGTFEFLY-ENGRFYFIEMNTR 292 >3OUU-A nrPDB Length = 446 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 52/224 (23%), Positives = 90/224 (40%), Gaps = 18/224 (8%) Query: 59 FIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALT 118 F +G E+ + + + G V A L DK ++K + Q AG+PV P Sbjct: 83 FPG-YGFLSENQNFVEICAKHNIKFIGPSVEAMNLMSDKSKAKQVMQRAGVPVIPG---- 137 Query: 119 RAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH----- 173 ++ ++ +G PVI+K + G GM V E L+ A A Sbjct: 138 -SDGALAGAEAAKKLAKEIGYPVILKAAAGGGGRGMRVVENEKDLEKAYWSAESEAMTAF 196 Query: 174 -DEEVLIEKWL-SGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGL-E 230 D + +EK++ + V ++G+ I + + L +E+ PA L + Sbjct: 197 GDGTMYMEKYIQNPRHIEVQVIGDSFGNVIHVGERDCSMQRRHQKLIEES----PAILLD 252 Query: 231 ASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 L +KA +G +G G + ++D + FY +E NT Sbjct: 253 EKTRTRLHETAIKAAKAIGYEGAGTFEFLVDKNLDFYFIEMNTR 296 >4RZQ-A nrPDB Length = 468 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 49/226 (21%), Positives = 92/226 (40%), Gaps = 22/226 (9%) Query: 61 ALHGRGG---EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVAL 117 A+H G E+ +E G + G L DK+ + + AG+P P Sbjct: 97 AIHPGYGFLSENADFAEQVERSGFTFIGPTADVIRLMGDKVSAIKAMKKAGVPCVPGSDG 156 Query: 118 TRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDAL-------RLA 170 + + +G P+I+K S G GM V +E+AL++++ + A Sbjct: 157 PVSNDIAKNKEIAK----RIGYPIIIKASGGGGGRGMRVVRSEDALEESIAMTKAEAKAA 212 Query: 171 FQHDEEVLIEKWLSGPEF-TVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-G 228 F +D V +EK+L P + +L + ++ + + + +E PA G Sbjct: 213 FNND-MVYMEKYLENPRHVEIQVLADTHGNAVYLAERDCSMQRRHQKVVEEA----PAPG 267 Query: 229 LEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 + ++ + A +G +G G + + +G+FY +E NT Sbjct: 268 ITEEVRRDIGSRCANACVEIGYRGAGTFEFLY-ENGEFYFIEMNTR 312 >3ORR-A nrPDB Length = 377 Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats. Identities = 59/239 (24%), Positives = 97/239 (40%), Gaps = 33/239 (13%) Query: 71 TLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQ 130 L+ + E +P G A L D+L K + AG V P++++ + +D Sbjct: 88 QLKLLCEKYNIP---QGYQAIQLLQDRLTEKETLKSAGTKVVPFISVKES------TDID 138 Query: 131 LAEISALGLPVIVKPSREGSSVGMSKV--VAENALQDALRLAFQHDEEVLIEKWLSGPEF 188 A I LG P IVK +R G G +V E LQ+ +L E + EK+L+ Sbjct: 139 KA-IETLGYPFIVK-TRFGGYDGKGQVLINNEKDLQEGFKLI--ETSECVAEKYLN---- 190 Query: 189 TVAILGEEILPSIRIQPSG-TFYDYEAKYLSDETQY--FCPAGLEASQEANLQALVLKAW 245 I E L R + TF+ + ++ + PA ++ + EA Q V K Sbjct: 191 ---IKKEVSLTVTRGNNNQITFFPLQENEHRNQILFKTIVPARIDKTAEAKEQ--VNKII 245 Query: 246 TTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILEL 304 ++ G ++ +DS+ Q Y+ E P + H + +SQ IL + Sbjct: 246 QSIHFIGTFTVEFFIDSNNQLYVNEIAPRPHNSGHYSI------EACDYSQFDTHILAV 298 >3JZF-A nrPDB Length = 486 Score = 155 bits (393), Expect = 1e-38, Method: Composition-based stats. Identities = 53/226 (23%), Positives = 88/226 (38%), Gaps = 22/226 (9%) Query: 61 ALHGRGG---EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVAL 117 A+H G E+ +E G + G L DK+ + + AG+P P Sbjct: 98 AIHPGYGFLSENANFAEQVERSGFIFIGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDG 157 Query: 118 TRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDAL-------RLA 170 + DK A +G PVI+K S G GM V + L ++ + A Sbjct: 158 PLGDD----MDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAELAQSISMTRAEAKAA 213 Query: 171 FQHDEEVLIEKWLSGPEF-TVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-G 228 F +D V +EK+L P + +L + +I + + + +E PA G Sbjct: 214 FSND-MVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRRHQKVVEEA----PAPG 268 Query: 229 LEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 + + KA +G +G G + + +G+FY +E NT Sbjct: 269 ITPELRRYIGERCAKACVDIGYRGAGTFEFLF-ENGEFYFIEMNTR 313 >3VOT-A nrPDB Length = 425 Score = 154 bits (388), Expect = 6e-38, Method: Composition-based stats. Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 40/245 (16%) Query: 73 QGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLA 132 L L GLP+T +K +++ + Q GL + Sbjct: 94 AEALNLPGLPFT-----TMENCRNKNKTRSILQQNGLNTPVFHEF---------HTLADL 139 Query: 133 EISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLA----------FQHDEE-VLIEK 181 E L P++VKP SS G+ +V L++A+R F H + ++ E+ Sbjct: 140 ENRKLSYPLVVKPVNGFSSQGVVRVDDRKELEEAVRKVEAVNQRDLNRFVHGKTGIVAEQ 199 Query: 182 WLSGPEF---TVAILGEEILPSI--RIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEAN 236 ++ GPEF T++I G + SI + G F+ +E Y PA L+ Sbjct: 200 FIDGPEFAIETLSIQGNVHVLSIGYKGNSKGPFF--------EEGVYIAPAQLKEETRLA 251 Query: 237 LQALVLKAWTTLGC-KGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFS 295 + V A + LG +G ++ LD DG Y++E G + S + G++F Sbjct: 252 IVKEVTGAVSALGIHQGPAHTELRLDKDGTPYVIEVGARIGGSGVSHY-IVKESTGINFM 310 Query: 296 QLVVR 300 QLV++ Sbjct: 311 QLVLQ 315 >1ULZ-A nrPDB Length = 451 Score = 143 bits (361), Expect = 8e-35, Method: Composition-based stats. Identities = 55/263 (20%), Positives = 94/263 (35%), Gaps = 19/263 (7%) Query: 22 SGAAVLAGLREGGIDAYPVDP---KEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLEL 78 + V I P+D K+ + +G + +G E+ M E Sbjct: 38 TARHVKLADEAYMIGTDPLDTYLNKQRIINLALEVGADAIHPG-YGFLAENAEFAKMCEE 96 Query: 79 MGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALG 138 G+ + G L DK RSK + + AG+PV P E+ A +G Sbjct: 97 AGITFIGPHWKVIELMGDKARSKEVMKKAGVPVVPGSDGVLKSLEEA-----KALAREIG 151 Query: 139 LPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEE------VLIEKWLSGP-EFTVA 191 PV++K + G G+ E L A + E+ +L+EK++ P Sbjct: 152 YPVLLKATAGGGGRGIRICRNEEELVKNYEQASREAEKAFGRGDLLLEKFIENPKHIEYQ 211 Query: 192 ILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCK 251 +LG++ I + + L + L + +V KA +G Sbjct: 212 VLGDKHGNVIHLGERDCSIQRRNQKLVEIAPSLI---LTPEKREYYGNIVTKAAKEIGYY 268 Query: 252 GWGRIDVMLDSDGQFYLLEANTS 274 G ++ + D +G Y +E NT Sbjct: 269 NAGTMEFIADQEGNLYFIEMNTR 291 >2VPQ-A nrPDB Length = 451 Score = 138 bits (348), Expect = 3e-33, Method: Composition-based stats. Identities = 43/236 (18%), Positives = 82/236 (34%), Gaps = 17/236 (7%) Query: 47 VTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQG 106 ++ S G V +G E+ + E L + G + K +K Sbjct: 66 LSIATSTGCDGVHPG-YGFLAENADFAELCEACQLKFIGPSYQSIQKMGIKDVAKAEMIK 124 Query: 107 AGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDA 166 A +PV P + + +G PVI+K + G G+ E L+ Sbjct: 125 ANVPVVPGSDGLMKDVSEA-----KKIAKKIGYPVIIKATAGGGGKGIRVARDEKELETG 179 Query: 167 LRLAFQHDEE------VLIEKWLSG-PEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSD 219 R+ Q + + +EK++ + I+G+ I + + L + Sbjct: 180 FRMTEQEAQTAFGNGGLYMEKFIENFRHIEIQIVGDSYGNVIHLGERDCTIQRRMQKLVE 239 Query: 220 ETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLD-SDGQFYLLEANTS 274 E L+ + ++A + + G I+ + D +D +FY +E NT Sbjct: 240 EAPSPI---LDDETRREMGNAAVRAAKAVNYENAGTIEFIYDLNDNKFYFMEMNTR 292 >3U9T-A nrPDB Length = 655 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 53/224 (23%), Positives = 87/224 (38%), Gaps = 20/224 (8%) Query: 62 LHGRGG---EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALT 118 +H G E+ E GL + G A K +K L + AG+P+ P Sbjct: 84 IHPGYGFLSENADFARACEEAGLLFLGPPAAAIDAMGSKSAAKALMEEAGVPLVPG---- 139 Query: 119 RAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH----- 173 E + E +G PV++K + G GM V E L +AL A + Sbjct: 140 -YHGEAQDLETFRREAGRIGYPVLLKAAAGGGGKGMKVVEREAELAEALSSAQREAKAAF 198 Query: 174 -DEEVLIEKWL-SGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPA-GLE 230 D +L+EK+L + + + + + + + +E PA GL Sbjct: 199 GDARMLVEKYLLKPRHVEIQVFADRHGHCLYLNERDCSIQRRHQKVVEEA----PAPGLG 254 Query: 231 ASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 A + ++A +G G G ++ +LD GQF+ +E NT Sbjct: 255 AELRRAMGEAAVRAAQAIGYVGAGTVEFLLDERGQFFFMEMNTR 298 >2DZD-A nrPDB Length = 461 Score = 136 bits (342), Expect = 1e-32, Method: Composition-based stats. Identities = 41/231 (17%), Positives = 86/231 (37%), Gaps = 17/231 (7%) Query: 51 KSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLP 110 K+ + +G E+ G+ + G + DK++++ AG+P Sbjct: 76 KAHDVDAIHPG-YGFLSENIQFAKRCREEGIIFIGPNENHLDMFGDKVKARHAAVNAGIP 134 Query: 111 VAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLA 170 V P ++ + +A A G P+I+K + G GM V +++ +++A A Sbjct: 135 VIPG-----SDGPVDGLEDVVAFAEAHGYPIIIKAALGGGGRGMRIVRSKSEVKEAFERA 189 Query: 171 FQH------DEEVLIEKWLSGP-EFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQY 223 +EV +EK + P V ILG+ + + + + + Sbjct: 190 KSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRHQKVVE---V 246 Query: 224 FCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 L + ++ ++G G ++ ++ D +FY +E N Sbjct: 247 APSVSLSDELRQRICEAAVQLMRSVGYVNAGTVEFLVSGD-EFYFIEVNPR 296 >3N6R-A nrPDB Length = 681 Score = 130 bits (326), Expect = 1e-30, Method: Composition-based stats. Identities = 44/239 (18%), Positives = 90/239 (37%), Gaps = 18/239 (7%) Query: 44 EVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLL 103 + + +++ G Q V +G E+ LE G+ + G A DK+ SK + Sbjct: 64 DKVMAAIRATGAQAVHPG-YGFLSENSKFAEALEAEGVIFVGPPKGAIEAMGDKITSKKI 122 Query: 104 WQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENAL 163 Q A + P + +D+ + + +G PV++K S G GM + Sbjct: 123 AQEANVSTVPGYMGLIED-----ADEAVKISNQIGYPVMIKASAGGGGKGMRIAWNDQEA 177 Query: 164 QDALRLAFQH------DEEVLIEKWL-SGPEFTVAILGEEILPSIRIQPSGTFYDYEAKY 216 ++ + + D+ + IEK++ + +L + I + + Sbjct: 178 REGFQSSKNEAANSFGDDRIFIEKFVTQPRHIEIQVLCDSHGNGIYLGERECSIQRRNQK 237 Query: 217 LSDETQYFCPAG-LEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 + +E P+ L+ + + + +G G ++ ++D FY LE NT Sbjct: 238 VVEEA----PSPFLDEATRRAMGEQAVALAKAVGYASAGTVEFIVDGQKNFYFLEMNTR 292 >2YL2-A nrPDB Length = 540 Score = 123 bits (309), Expect = 9e-29, Method: Composition-based stats. Identities = 48/236 (20%), Positives = 83/236 (35%), Gaps = 29/236 (12%) Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPW------VAL 117 G E+ L +L G+ + G A DK+ S ++ Q AG+P PW V Sbjct: 133 GHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDW 192 Query: 118 TRAEFEKGL---------------SDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENA 162 +F K + D L +G PV++K S G G+ KV + Sbjct: 193 QENDFSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD 252 Query: 163 LQDALRLAFQH---DEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSD 219 + R ++ V IL ++ +I + + + + Sbjct: 253 FPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIE 312 Query: 220 ETQYFCPAGL-EASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 E PA + + +++ +K +G G ++ + DG FY LE N Sbjct: 313 EA----PATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPR 364 >5MLK-A nrPDB Length = 614 Score = 104 bits (259), Expect = 6e-23, Method: Composition-based stats. Identities = 39/226 (17%), Positives = 75/226 (33%), Gaps = 20/226 (8%) Query: 60 IALHGRGG---EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVA 116 A+H G E+ + GL + G + DK+ ++ + A P+ P Sbjct: 100 NAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPG-- 157 Query: 117 LTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDE- 175 +D+ +A GLP+ +K + G GM + + + A + Sbjct: 158 ---TPDPVKGADEVVAFAEEYGLPIAIKAAHGGGGKGMKVARTIDEIPELYESAVREATA 214 Query: 176 -----EVLIEKWLS-GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAG- 228 E +E++L ++ ++ + + L +E PA Sbjct: 215 AFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCSLQRRYQKLVEEA----PAPF 270 Query: 229 LEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 L Q + + G G ++ ++ DG LE NT Sbjct: 271 LTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGLISFLEVNTR 316 >5H80-A nrPDB Length = 494 Score = 103 bits (258), Expect = 8e-23, Method: Composition-based stats. Identities = 45/224 (20%), Positives = 74/224 (33%), Gaps = 21/224 (9%) Query: 62 LHGRGG---EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALT 118 +H G E+ GL + G L DK R++ L Q G+PV P Sbjct: 107 VHPGYGFLSENADFARACAQAGLVFVGPDPDTLDLFGDKSRARGLAQRLGVPVIPG---- 162 Query: 119 RAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDE--- 175 + L + + G PV++K G GM V L A A + Sbjct: 163 -TDGATTLEEAAAFMQAQGGAPVMLKACSGGGGRGMRVVRQAGDLAAAFEQASREARLAV 221 Query: 176 ---EVLIEKWLS-GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAG-LE 230 ++ E+ + V + G+ + + L + F PA L Sbjct: 222 GQGDLYAERLIERARHIEVQVAGDGQ-SVTHLWERDCTVQRRHQKLLE----FAPAPHLP 276 Query: 231 ASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 + L L+ + + G + ++ G FY +EAN Sbjct: 277 QAVRTALIGAALQLAQEVKYRCLGTFEFLVTPGGDFYFIEANPR 320 >3JRW-A nrPDB Length = 587 Score = 103 bits (257), Expect = 8e-23, Method: Composition-based stats. Identities = 43/237 (18%), Positives = 82/237 (34%), Gaps = 30/237 (12%) Query: 64 GRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPW------VAL 117 G E+ L +L G+ + G A DK+ S ++ Q +P PW V Sbjct: 148 GHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEW 207 Query: 118 TRAEFEKG----------------LSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAEN 161 T + ++G D+ L +G P+++K S G G+ K + Sbjct: 208 TEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAE 267 Query: 162 ALQDALRLAFQH---DEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS 218 R L++ V IL ++ ++ + + + Sbjct: 268 DFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIV 327 Query: 219 DETQYFCPAGLEA-SQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 +E PA + + ++ ++ T+G G ++ + DG F+ LE N Sbjct: 328 EEA----PATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPR 380 >1W93-A nrPDB Length = 553 Score = 100 bits (249), Expect = 8e-22, Method: Composition-based stats. Identities = 38/215 (17%), Positives = 75/215 (34%), Gaps = 26/215 (12%) Query: 83 YTGSGVMASALSMDKLRSKLLWQGAGLPVAPW----------------VALTRAEFEKG- 125 + G A DK+ S ++ Q A +P PW V++ ++KG Sbjct: 159 FIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGC 218 Query: 126 --LSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQH---DEEVLIE 180 + L + +G PV++K S G G+ +V E A +++ Sbjct: 219 CTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMK 278 Query: 181 KWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL 240 V +L ++ +I + + + +E +A ++ Sbjct: 279 LAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIA---KAETFHEMEKA 335 Query: 241 VLKAWTTLGCKGWGRIDVMLD-SDGQFYLLEANTS 274 ++ +G G ++ + DG+FY LE N Sbjct: 336 AVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPR 370 >3LN7-A nrPDB Length = 757 Score = 97.4 bits (241), Expect = 7e-21, Method: Composition-based stats. Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 19/147 (12%) Query: 73 QGMLELMG--LPYTGSGVMASALSM-------DKLRSKLLWQGAGLPVAPWVALTRAEFE 123 Q + G + Y +G M S S +K+ +K + Q AG V V T E Sbjct: 457 QFLCLKYGDHIEYVKNGNMTSHDSYISPLIMENKVVTKKVLQKAGFNVPQSVEFT--SLE 514 Query: 124 KGLSDKQLAEISALGLPVIVKPSREGSSVGMSK----VVAENALQDALRLAFQHDEEVLI 179 K ++ L E A V++KP +G++ V AL +AF+ D+EV++ Sbjct: 515 KAVASYALFENRA----VVIKPKSTNYGLGITIFQQGVQNREDFAKALEIAFREDKEVMV 570 Query: 180 EKWLSGPEFTVAILGEEILPSIRIQPS 206 E +L G E+ +LG+E L + P+ Sbjct: 571 EDYLVGTEYRFFVLGDETLAVLLRVPA 597 >3AX6-A nrPDB Length = 380 Score = 95.9 bits (237), Expect = 2e-20, Method: Composition-based stats. Identities = 38/221 (17%), Positives = 72/221 (32%), Gaps = 30/221 (13%) Query: 68 EDGTLQGMLELMGLPY-TGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGL 126 E +Q + +L Y + DK K + G+PV + + E Sbjct: 71 EHIDVQTLKKLYNEGYKIHPSPYTLEIIQDKFVQKEFLKKNGIPVPEYKLVKDLE----- 125 Query: 127 SDKQLAEISALGLPVIVKPSREG-SSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLS- 184 +++ G PV+ K + G G+ + E L++A++ E +E+++ Sbjct: 126 -----SDVREFGFPVVQKARKGGYDGRGVFIIKNEKDLENAIK------GETYLEEFVEI 174 Query: 185 GPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQY----FCPAGLEASQEANLQAL 240 E V + E Y Y ++ PA +E + + Sbjct: 175 EKELAVMVARNEKGEI-------ACYPVVEMYFDEDANICDTVIAPARIEEKYSKIAREI 227 Query: 241 VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHS 281 L G I++ L G+ + E P + H Sbjct: 228 ATSVVEALEGVGIFGIEMFLTKQGEILVNEIAPRPHNSGHY 268 >3QFF-A nrPDB Length = 389 Score = 92.4 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 54/306 (17%), Positives = 103/306 (33%), Gaps = 49/306 (16%) Query: 1 MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDP-KEVDVTQLKSMGFQKVF 59 M D ++L G + G + +E G +DP K Q+ + + Sbjct: 4 MLDMTRIILPGKTIGIIGGGQLGRMMALAAKEMGYKIAVLDPTKNSPCAQVADIEIVASY 63 Query: 60 IALHGRGGEDGTLQGMLELMGL-------------------PYTGSGVMASALSMDKLRS 100 L +Q + E+ + Y G + + ++ Sbjct: 64 DDLK-------AIQHLAEISDVVTYEFENIDYRCLQWLEKHAYLPQGSQLLSKTQNRFTE 116 Query: 101 KLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKV--V 158 K + AGLPVA + + E + I+ L P ++K + G G +V Sbjct: 117 KNAIEKAGLPVATYRLVQNQE-------QLTEAIAELSYPSVLK-TTTGGYDGKGQVVLR 168 Query: 159 AENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIR-IQPSGTFYDYEAKYL 217 +E + +A +LA + E ++EKW+ E V+++ IR + + Sbjct: 169 SEADVDEARKLA--NAAECILEKWV-PFEKEVSVI------VIRSVSGETKVFPVAENIH 219 Query: 218 SDETQY--FCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSP 275 + + PA + A L G +++ +DG+ Y+ E P Sbjct: 220 VNNILHESIVPARITEELSQKAIAYAKVLADELELVGTLAVEMFATADGEIYINELAPRP 279 Query: 276 GMTSHS 281 + H Sbjct: 280 HNSGHY 285 >5KS8-A nrPDB Length = 405 Score = 83.5 bits (205), Expect = 9e-17, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 3/92 (3%) Query: 183 LSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL 242 ++ V +L + I + + L + L +Q + L + Sbjct: 136 VNPRHIEVQVLADSHGNVIHLFERDCSIQRRNQKLIE---IAPSPQLSKAQREYIGNLAV 192 Query: 243 KAWTTLGCKGWGRIDVMLDSDGQFYLLEANTS 274 KA +G K G ++ +LDSD FY +E NT Sbjct: 193 KAAKAVGYKNAGTVEFLLDSDNNFYFMEMNTR 224 Score = 44.2 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 61 ALHGRGG---EDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVA 112 ALH G E+ L + G+ + G DK++++ AG+P Sbjct: 76 ALHPGYGFLSENPELAEICARRGIKFIGPDAKVIRQMGDKIQARTAMIKAGIPCV 130 >3WO0-A nrPDB Length = 470 Score = 80.5 bits (197), Expect = 8e-16, Method: Composition-based stats. Identities = 47/252 (18%), Positives = 98/252 (38%), Gaps = 33/252 (13%) Query: 72 LQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQL 131 + E +GL G+GV A+ + DK + + + AG+ + Sbjct: 117 MAKACERLGLR--GAGVQAAENARDKNKMRDAFNKAGVKSIK-------NKRVTTLEDFR 167 Query: 132 AEISALGLPVIVKPSREGSSVGMSKVVA----ENALQDA--------LRLAFQHDEEVLI 179 A + +G P+I+KP+ SS+G++ + E+ + A + + Sbjct: 168 AALEEIGTPLILKPTYLASSIGVTLITDTETAEDEFNRVNDYLKSINVPKAVTFEAPFIA 227 Query: 180 EKWLSGPEFTVAILGEEILPSIRIQP---SGTFY-----DYEAKYLSDETQYFCPAGLEA 231 E++L G E+ E I I+ G ++ D + ET + P+ L+ Sbjct: 228 EEFLQG-EYGDWYQTEGYSDYISIEGIMADGEYFPIAIHDKTPQIGFTETSHITPSILDE 286 Query: 232 SQEANLQALVLKAWTTLGCKGWGR-IDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQA 290 + + KA LG + ++ L + + L+E+ +++P + Sbjct: 287 EAKKKIVEAAKKANEGLGLQNCATHTEIKLMKNREPGLIESAAR--FAGWNMIPNIKKVF 344 Query: 291 GMSFSQLVVRIL 302 G+ +QL++ +L Sbjct: 345 GLDMAQLLLDVL 356 >4DIM-A nrPDB Length = 403 Score = 80.1 bits (196), Expect = 1e-15, Method: Composition-based stats. Identities = 45/240 (18%), Positives = 90/240 (37%), Gaps = 30/240 (12%) Query: 71 TLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAP-WVALTRAEFEKGLSDK 129 +L + + L G A+ + DK + K ++ + A +V E + L Sbjct: 86 SLARICDKENL--VGLNEEAAIMCGDKYKMKEAFKKYNVNTARHFVVRNENELKNAL--- 140 Query: 130 QLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEE--VLIEKWLSGPE 187 L LPVIVK + S G+ E D + ++E+++ G E Sbjct: 141 -----ENLKLPVIVKATDLQGSKGIYIAKKEEEAIDGFNETMNLTKRDYCIVEEFIEGYE 195 Query: 188 FTVA--ILGEEILPSIRIQPSGTFYDYEAKYLSDETQ---YFCPAGLEASQEANLQALVL 242 F + ++L + P G + Y+S ++ P ++ + V Sbjct: 196 FGAQAFVYKNDVLFVM---PHG-----DETYMSHTAVPVGHYVPLDVKDDIIEKTKTEVK 247 Query: 243 KAWTTLGCKGWG-RIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRI 301 KA LG +D++L D + Y++E G ++ L + G+ + +++ + Sbjct: 248 KAIKALGLNNCAVNVDMIL-KDNEVYIIELTGRVG--ANCLPELVEINYGIEYYKMIASM 304 >4E4T-A nrPDB Length = 419 Score = 79.7 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 44/210 (20%), Positives = 72/210 (34%), Gaps = 16/210 (7%) Query: 78 LMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISAL 137 L + A++ D++ K + +G+PVAP V + A L D L + Sbjct: 115 LARTTFVAPAGRCVAVAQDRIAEKRFIEASGVPVAPHVVIESAAALAALDDAALDAV--- 171 Query: 138 GLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEI 197 LP I+K +R G G +V A + A ++EK L ++ V+ L Sbjct: 172 -LPGILKTARLG-YDGKGQVRVSTAREARDAHAALGGVPCVLEKRL-PLKYEVSAL---- 224 Query: 198 LPSIRIQP-SGTFYDYEAKYLSDE--TQYFCPAGLEASQE-ANLQALVLKAWTTLGCKGW 253 R + + PA + Q ++ TLG G Sbjct: 225 --IARGADGRSAAFPLAQNVHHNGILALTIVPAPAADTARVEEAQQAAVRIADTLGYVGV 282 Query: 254 GRIDVMLDSDGQFYLLEANTSPGMTSHSLV 283 ++ + DG F E P + H V Sbjct: 283 LCVEFFVLEDGSFVANEMAPRPHNSGHYTV 312 >3K5H-A nrPDB Length = 403 Score = 75.8 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 41/229 (17%), Positives = 72/229 (31%), Gaps = 28/229 (12%) Query: 84 TGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIV 143 A +K K + G+P+A L E ++ LG P+++ Sbjct: 111 IEPSWQAIRTIQNKFNQKEHLRKYGIPMAEHREL----VENTPAELAK-VGEQLGYPLML 165 Query: 144 KPSREG-SSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIR 202 K G +V +++ + +AL D + EKW + L I Sbjct: 166 KSKTMAYDGRGNFRVNSQDDIPEALEAL--KDRPLYAEKW---------AYFKMELAVIV 214 Query: 203 IQPSGTFYDYEAKYLSDETQY----FCPAG-LEASQEANLQALVLKAWTTLGCKGWGRID 257 ++ Y E + PA + + Q L KA KG ++ Sbjct: 215 VKTKDEVLSYPTVETVQEDSICKLVYAPARNVSDAINQKAQELARKAVAAFDGKGVFGVE 274 Query: 258 VMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 306 + L D L E + + H + G + SQ + + D Sbjct: 275 MFLLEDDSIMLCEIASRIHNSGHYTI------EGCALSQFDAHLRAILD 317 >2Z04-A nrPDB Length = 365 Score = 73.9 bits (180), Expect = 8e-14, Method: Composition-based stats. Identities = 44/224 (19%), Positives = 86/224 (38%), Gaps = 29/224 (12%) Query: 86 SGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKP 145 A + ++R KL + G PV ++ + R D+ + + + LPV++K Sbjct: 82 PNPQALYVKKSRIREKLFLKKHGFPVPEFLVIKR--------DEIIDALKSFKLPVVIKA 133 Query: 146 SREGSSVGMSKVVAENALQDALRLAFQHDEE--VLIEKWLSGPEFTVAILGEEILPSIRI 203 + G G + + L+DA ++ HD+E +IE+++ E ++ +G Sbjct: 134 EKLG-YDGKGQYRIKK-LEDANQVVKNHDKEESFIIEEFVK-FEAEISCIG-----VRDR 185 Query: 204 QPSGTFYDYEAKYLSDETQYF--CP-AGLEASQEANLQALVLKAWTTLGCKGWGRIDVML 260 + FY + + P A L+ ++E + + L G ++ L Sbjct: 186 EGKTYFYPQPFNKHEEGILIYNYVPYAKLKEAEE-----ITKRLMELLDIVGVFTVEFFL 240 Query: 261 DSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILEL 304 DG+ + E T H + A F L+ I E+ Sbjct: 241 LKDGRVLINEFAPRVHNTGHWTLDGAYTS---QFENLLRAITEM 281 >2YW2-A nrPDB Length = 424 Score = 72.0 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 58/302 (19%), Positives = 99/302 (32%), Gaps = 46/302 (15%) Query: 6 AVLLGGTSAEREVSLNSGA-----AVLAGLREGGIDAYP--VDPKEVDVTQL----KSMG 54 +++G E ++ + GI VD DV +L K+ G Sbjct: 3 VLVVGNGGREHAIAWKVAQSPLVKELYVAKGNAGIWEIAKRVDISPTDVEKLAEFAKNEG 62 Query: 55 FQKVF-----IALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGL 109 + G E E GL G A+ L K +K + G+ Sbjct: 63 VDFTIVGPEAPLVEGIVDE-------FEKRGLKIFGPNKEAAKLEGSKAFAKTFMKKYGI 115 Query: 110 PVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDAL-- 167 P A + T E K + +G P++VK + G + L Sbjct: 116 PTARYEVFTDFEKAKEY-------VEKVGAPIVVKADGLAAGKGAVVCETVEKAIETLDR 168 Query: 168 ---RLAFQHDEE-VLIEKWLSGPE--FTVAILGEEILPSIRIQPSGTFYDYEAKYLSDET 221 + F E V+IE++L G E + V I G+ +P Q D + + Sbjct: 169 FLNKKIFGKSSERVVIEEFLEGEEASYIVMINGDRYVPLPTSQDHKRLLDEDKGPNTGGM 228 Query: 222 QYFCPAG-LEASQEANLQ-ALVLKAWTTLG-----CKGWGRIDVMLDSDGQFYLLEANTS 274 + P + E ++ +V + L +G+ +M+ +G +LE N Sbjct: 229 GAYSPTPVINEEVEKRIREEIVERVIKGLKEEGIYYRGFLYAGLMITKEG-PKVLEFNVR 287 Query: 275 PG 276 G Sbjct: 288 LG 289 >3LN6-A nrPDB Length = 750 Score = 71.6 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 50/130 (38%), Gaps = 16/130 (12%) Query: 81 LPYTGSGVMASALSM-------DKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAE 133 + Y +G M S + +K+ +K + P T + + + Sbjct: 462 IEYVKNGNMTSKDNYIVPLAMANKVVTKKILDEKHFPTPFGDEFTDRKEALNYFSQIQDK 521 Query: 134 ISALGLPVIVKPSREGSSVGMSKVVAENAL---QDALRLAFQHDEEVLIEKWLSGPEFTV 190 P++VKP +G+S L + A+ +AF D +L+E+++ G E+ Sbjct: 522 ------PIVVKPKSTNFGLGISIFKTSANLASYEKAIDIAFTEDSAILVEEYIEGTEYRF 575 Query: 191 AILGEEILPS 200 +L + + Sbjct: 576 FVLEGDCIAV 585 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 7/67 (10%) Query: 156 KVVAENALQDALRLAFQHDEEVLIEK-------WLSGPEFTVAILGEEILPSIRIQPSGT 208 KV E+ L AF++D +EK +SG + + + E + + + Sbjct: 106 KVREEDIQIAQLEDAFEYDYRKYLEKTYGKLIQSISGIHYNLGLGQELLTSLFELSQADN 165 Query: 209 FYDYEAK 215 D++ + Sbjct: 166 AIDFQNQ 172 >2CZG-A nrPDB Length = 433 Score = 71.6 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 36/228 (15%), Positives = 76/228 (33%), Gaps = 25/228 (10%) Query: 83 YTGSGVMASALSMDKLRSKLLW-QGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPV 141 + A+ ++M + R + + A +P + ++ D+ +G P Sbjct: 107 FVVPNARATWIAMHRERLRETLVKEAKVPTSRYM-------YATTLDELYEACEKIGYPC 159 Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLA----FQHDEEVLIEKWL----SGPEFTVAIL 193 K S G V + A A E++++E+ + E V Sbjct: 160 HTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEEHIDFDVEVTELAVRHF 219 Query: 194 GEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGW 253 E Y + Y + + PA + E + + + LG G Sbjct: 220 DENGEIVTTFPKPVGHYQIDGDYHAS----WQPAEISEKAEREVYRIAKRITDVLGGLGI 275 Query: 254 GRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRI 301 +++ + D + + E + P T +V +A+ G FS+ + + Sbjct: 276 FGVEMFVKGD-KVWANEVSPRPHDTG--MVTLASHPPG--FSEFALHL 318 >3AW8-A nrPDB Length = 369 Score = 71.6 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 40/220 (18%), Positives = 74/220 (33%), Gaps = 26/220 (11%) Query: 86 SGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKP 145 A ++ D+LR K +QG G+P P+ + E + + +GLP ++K Sbjct: 86 PPAKALEVAQDRLREKTFFQGLGVPTPPFHPVDGPEDLEE-------GLKRVGLPALLK- 137 Query: 146 SREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQ- 204 +R G G + + ++AL LI + + V++L ++R + Sbjct: 138 TRRGGYDGKGQALVRTE-EEALEALKALGGRGLILEGFVPFDREVSLL------AVRGRT 190 Query: 205 PSGTFYDYEAKYLSDETQY--FCPA-GLEASQEANLQALVLKAWTTLGCKGWGRIDVMLD 261 FY PA G + + +A L+A L G ++ Sbjct: 191 GEVAFYPLVENRHWGGILRLSLAPAPGASEALQKKAEAYALRAMEALDYVGVLALEFFQV 250 Query: 262 SDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRI 301 + + E + H G SQ + Sbjct: 251 GE-ELLFNEMAPRVHNSGH------WTIEGAETSQFENHL 283 >1EZ1-A nrPDB Length = 392 Score = 70.8 bits (172), Expect = 7e-13, Method: Composition-based stats. Identities = 33/192 (17%), Positives = 62/192 (32%), Gaps = 21/192 (10%) Query: 100 SKLLWQGAGLPVAPWVALTRAEFEKGLSDKQ---LAEISALGLPVIVKPSREGSSVGMSK 156 +KL G+ L +D + ++ +G P IVKP S G + Sbjct: 108 TKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTF 167 Query: 157 VVAENALQDALRLAFQHDE----EVLIEKWLSGPEFTVAILGEEILPSIR----IQPSGT 208 + + L A + A Q V++E + +F + +L + + + Sbjct: 168 IRSAEQLAQAWKYAQQGGRAGAGRVIVE-GVVKFDFEITLLTVSAVDGVHFCAPVGHRQE 226 Query: 209 FYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYL 268 DY + P + Q + K LG G +++ + D + Sbjct: 227 DGDYRESWQ--------PQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGD-EVIF 277 Query: 269 LEANTSPGMTSH 280 E + P T Sbjct: 278 SEVSPRPHDTGM 289 >4IZO-A nrPDB Length = 419 Score = 69.7 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 44/214 (20%), Positives = 73/214 (34%), Gaps = 24/214 (11%) Query: 78 LMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISAL 137 L + A++ D++ K +G+PVAP V + A L+D LA + Sbjct: 115 LAQSTFVAPAGRCVAIAQDRIAEKRFIAASGVPVAPHVVIESAAQLAALADADLAAV--- 171 Query: 138 GLPVIVKPSREG-SSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAIL--- 193 LP I+K +R G G +V +DA ++EK L ++ V+ L Sbjct: 172 -LPGILKTARLGYDGKGQVRVATAQEARDAYGSLG--GVPCVLEKRL-PLKYEVSALIAR 227 Query: 194 ----GEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLG 249 + P + G + PA +A Q + +L Sbjct: 228 GANGASAVFPLAQNTHHGGILSL--------SVVPAPAASDALVRDA-QQAAARIADSLD 278 Query: 250 CKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLV 283 G ++ + DG E P + H V Sbjct: 279 YVGVLCVEFFVLEDGSLVANEMAPRPHNSGHYTV 312 >2IP4-A nrPDB Length = 417 Score = 68.5 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 48/215 (22%), Positives = 86/215 (40%), Gaps = 18/215 (8%) Query: 72 LQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQL 131 + + GL G A+ + K +K L + G+P A + + L Sbjct: 77 IADAFQARGLLLFGPTQKAAMIEGSKAFAKGLMERYGIPTARYRVFREPL-------EAL 129 Query: 132 AEISALGLPVIVKPSREGSSVGMSKVVAENALQDALR--LAFQHDEEVLIEKWLSGPEFT 189 A + +G+PV+VK S + G++ + + A+ L EV++E++L G E T Sbjct: 130 AYLEEVGVPVVVKDSGLAAGKGVTVAFDLHQAKQAVANILNRAEGGEVVVEEYLEGEEAT 189 Query: 190 VAIL--GEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVL----K 243 V L GE ILP + Q D + ++ P ++ + ++ +L + Sbjct: 190 VLALTDGETILPLLPSQDHKRLLDGDQGPMTGGMGAVAPYPMDEATLRRVEEEILGPLVR 249 Query: 244 AWTTLG--CKGWGRIDVMLDSDGQFYLLEANTSPG 276 G +G +ML +G +LE N G Sbjct: 250 GLRAEGVVYRGVVYAGLMLTREG-PKVLEFNARFG 283 >4IWX-A nrPDB Length = 320 Score = 67.4 bits (163), Expect = 7e-12, Method: Composition-based stats. Identities = 41/232 (17%), Positives = 88/232 (37%), Gaps = 26/232 (11%) Query: 75 MLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEI 134 E++G Y + +A A + DKLRS L G+ L D Sbjct: 99 QFEMLG-SYPLNESVAIARARDKLRSMQLLARQGI------DLPVTGIAHSPDDTSDLID 151 Query: 135 SALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWL---SGPEFTVA 191 G P++VK +G+ A + + + +L+++++ G + Sbjct: 152 MVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCL 211 Query: 192 ILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCK 251 ++G+E++ +I + D+ + A + + + +KA T+ Sbjct: 212 VVGDEVVAAIERRAKEG--DFRSNLHRGGAASV--ASITPQERE----IAIKAARTMALD 263 Query: 252 GWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILE 303 G +D++ + G ++E N SPG+ + G+ + ++R +E Sbjct: 264 VAG-VDILRANRG-PLVMEVNASPGLEGIE------KTTGIDIAGKMIRWIE 307 >2XD4-A nrPDB Length = 422 Score = 67.0 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 46/217 (21%), Positives = 82/217 (37%), Gaps = 25/217 (11%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 E GL G A+ + K +K L + +P A + T D+ A + Sbjct: 82 FEKAGLHVFGPSKAAAIIEGSKQFAKDLMKKYDIPTAEYETFT-------SFDEAKAYVQ 134 Query: 136 ALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEE-------VLIEKWLSGPEF 188 G P+++K + G++ + E L F DE+ V+IE++LSG EF Sbjct: 135 EKGAPIVIKADGLAAGKGVTVAMTEEEAIACLHD-FLEDEKFGDASASVVIEEYLSGEEF 193 Query: 189 TV--AILGEEILPSIRIQPSGTFYDYE--AKYLSDETQYFCPAGLEASQEANLQALVLKA 244 ++ + GE++ P + Q +D + P E + ++ +V A Sbjct: 194 SLMAFVKGEKVYPMVIAQDHKRAFDGDKGPNTGGMGAYSPVPQISEETVRHAVETIVKPA 253 Query: 245 WTTL-----GCKGWGRIDVMLDSDGQFYLLEANTSPG 276 + G +ML +G ++E N G Sbjct: 254 AKAMVQEGRSFTGVLYAGLMLTENGSK-VIEFNARFG 289 >2PN1-A nrPDB Length = 331 Score = 67.0 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 47/256 (18%), Positives = 84/256 (32%), Gaps = 34/256 (13%) Query: 44 EVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLL 103 + +T + G + + G + +G+ S A L DK Sbjct: 62 DHLLTLCQDEGVTALLTLIDPELGLLAQATERFQAIGVTVIVSPYAACELCFDKYTMYEY 121 Query: 104 WQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENAL 163 G+ A R ++ LA + LPV VKP +S+ + +V Sbjct: 122 CLRQGI------AHARTYATMASFEEALAA-GEVQLPVFVKPRNGSASIEVRRVETVEE- 173 Query: 164 QDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQY 223 + F + ++++++ L G E V + + I + + F + + Sbjct: 174 ---VEQLFSKNTDLIVQELLVGQELGV----DAYVDLISGKVTSIFI---------KEKL 217 Query: 224 FCPAGLEASQEANLQALVLKAWTTL----GCKGWGRIDVMLDSDGQFYLLEANTSPGMTS 279 AG + L+ V + + G G D+ D G YL E N G Sbjct: 218 TMRAGETDKSRSVLRDDVFELVEHVLDGSGLVGPLDFDLF-DVAGTLYLSEINPRFGGG- 275 Query: 280 HSLVPMAARQAGMSFS 295 P A G++F Sbjct: 276 ---YPHAYEC-GVNFP 287 >3VPD-A nrPDB Length = 281 Score = 66.6 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 74/204 (36%), Gaps = 28/204 (13%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 L +G+P + DK + + AGLP T E + L + Sbjct: 69 LTALGIPVV-NRPEVIEACGDKWATSVALAKAGLPQPKTALATDRE-------EALRLME 120 Query: 136 ALGLPVIVKPSREGSSVGMSKVVAENALQDALRL-----AFQHDEEVLIEKWLS--GPEF 188 A G PV++KP ++KV A + L FQH + I++++ G + Sbjct: 121 AFGYPVVLKPVIGSWGRLLAKVTDRAAAEALLEHKEVLGGFQH-QLFYIQEYVEKPGRDI 179 Query: 189 TVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTL 248 V ++GE + +I Y A ++++ + + L + A + Sbjct: 180 RVFVVGERAIAAI--------YRRSAHWITNTARGGQAENCP--LTEEIARLSVGAAEAV 229 Query: 249 GCKGWGRIDVMLDSDGQFYLLEAN 272 G G +D+ G + E N Sbjct: 230 G-GGVVAVDLFESERG-LLVNEVN 251 >4WD3-A nrPDB Length = 413 Score = 64.7 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 72/205 (35%), Gaps = 17/205 (8%) Query: 85 GSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVK 144 G G + +KL K + G+PVA ++ +++ E A LG P+IVK Sbjct: 99 GPGFETALYMTNKLAMKTKLKMEGIPVADFLCVSQVEDIP-------AAGEKLGWPIIVK 151 Query: 145 PSREGSSVGMSKVVAENALQD------ALRLAFQHDEEVLIEKWLSGPEFTVAIL-GEEI 197 P+ ++ + + + +D L +++ ++ EK + EF L + Sbjct: 152 PALGSGALNTFIIHSLDHYEDLYSTSGGLGELKKNNSLMIAEKCIEMEEFHCDTLYADGE 211 Query: 198 LPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRID 257 + + I + + A LQ V +A+ G G ++ Sbjct: 212 ILFVSISKYTVPLLKGMAKIQGSFILSQNDPVYAEI-LELQKSVAQAFRITD--GPGHLE 268 Query: 258 VMLDSDGQFYLLEANTSPGMTSHSL 282 + G+ + E G S Sbjct: 269 IYRTHSGELIVGEIAMRIGGGGISR 293 >1GSO-A nrPDB Length = 431 Score = 61.2 bits (147), Expect = 6e-10, Method: Composition-based stats. Identities = 41/216 (18%), Positives = 77/216 (35%), Gaps = 22/216 (10%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 GL G A+ L K +K +P A + T + LA + Sbjct: 86 FRAAGLKIFGPTAGAAQLEGSKAFTKDFLARHKIPTAEYQNFTE-------VEPALAYLR 138 Query: 136 ALGLPVIVKPSREGSSVGMSKVVAENALQDALRL-----AFQH-DEEVLIEKWLSGPE-- 187 G P+++K + G+ + + A+ AF ++IE++L G E Sbjct: 139 EKGAPIVIKADGLAAGKGVIVAMTLEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEAS 198 Query: 188 FTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGL--EASQEANLQALVLKAW 245 F V + GE +LP Q D + + + PA + + + ++ ++ Sbjct: 199 FIVMVDGEHVLPMATSQDHKRVGDKDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTV 258 Query: 246 TTLG-----CKGWGRIDVMLDSDGQFYLLEANTSPG 276 + G+ +M+D G ++E N G Sbjct: 259 KGMAAEGNTYTGFLYAGLMIDKQGNPKVIEFNCRFG 294 >5VEV-A nrPDB Length = 431 Score = 60.8 bits (146), Expect = 7e-10, Method: Composition-based stats. Identities = 42/216 (19%), Positives = 74/216 (34%), Gaps = 22/216 (10%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 GL G A+ L K +K +P A + A+ +++ Sbjct: 90 FRAAGLKIFGPTQYAAQLESSKDFAKAFMVKYNIPTAQYQTFENADAAHDYVNQK----- 144 Query: 136 ALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAF------QHDEEVLIEKWLSGPE-- 187 G P+++K + G+ + + A+ E V+IE +L G E Sbjct: 145 --GAPIVIKADGLVAGKGVIVAMTLDEAHAAIDDMLLGNKMGNAGERVVIEDFLQGEEAS 202 Query: 188 FTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGL--EASQEANLQALVLKAW 245 F V + G +LP Q D + + + PA + A E + ++L Sbjct: 203 FIVMVDGNHVLPMATSQDHKRLLDGDKGPNTGGMGAYSPAPVVTPAVYERAMNEIILPTV 262 Query: 246 TTLG-----CKGWGRIDVMLDSDGQFYLLEANTSPG 276 + G+ +M+D G Y +E N G Sbjct: 263 AGMKAEGHEFTGFLYAGLMIDQSGAPYTIEFNCRFG 298 >3ETH-A nrPDB Length = 355 Score = 60.0 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 46/215 (21%), Positives = 69/215 (32%), Gaps = 29/215 (13%) Query: 96 DKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMS 155 D+L K L+ LP APW L + D LG IVK R G G Sbjct: 79 DRLTQKQLFDKLHLPTAPWQLLAERSEWPAVFD-------RLGELAIVK-RRTGGYDGRG 130 Query: 156 KVV-AENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGT-FYDYE 213 + N + + E ++E+ ++ GE L R T FY Sbjct: 131 QWRLRANETEQLPAECY---GECIVEQGIN-------FSGEVSLVGARGFDGSTVFYPLT 180 Query: 214 AKYLSDETQYFCPA--GLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEA 271 D A A Q+A + ++ LG G ++ + G + E Sbjct: 181 HNLHQDGILRTSVAFPQANAQQQARAEEMLSAIMQELGYVGVMAMECFVTPQG-LLINEL 239 Query: 272 NTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD 306 + H Q G S SQ + + + D Sbjct: 240 APRVHNSGH------WTQNGASISQFELHLRAITD 268 >3MJF-A nrPDB Length = 431 Score = 59.3 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 44/216 (20%), Positives = 78/216 (36%), Gaps = 22/216 (10%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 GL G A+ L K +K +P A + T E LA + Sbjct: 87 FRAAGLAIFGPTQAAAQLEGSKAFTKDFLARHNIPSAEYQNFTDVEA-------ALAYVR 139 Query: 136 ALGLPVIVKPSREGSSVGMSKVVAENALQDALRL-----AFQH-DEEVLIEKWLSGPE-- 187 G P+++K + G+ + + + A+ AF +++E++L G E Sbjct: 140 QKGAPIVIKADGLAAGKGVIVAMTQEEAETAVNDMLAGNAFGDAGHRIVVEEFLDGEEAS 199 Query: 188 FTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAG-LEASQEANLQALVL---- 242 F V + GE +LP Q D + + + PA + + V+ Sbjct: 200 FIVMVDGENVLPMATSQDHKRVGDGDTGPNTGGMGAYSPAPVVTDDVHQRVMDQVIWPTV 259 Query: 243 KAWTTLG--CKGWGRIDVMLDSDGQFYLLEANTSPG 276 + G G+ +M+ +DGQ ++E N G Sbjct: 260 RGMAAEGNIYTGFLYAGLMISADGQPKVIEFNCRFG 295 >2YS6-A nrPDB Length = 451 Score = 57.7 bits (138), Expect = 7e-09, Method: Composition-based stats. Identities = 45/212 (21%), Positives = 79/212 (37%), Gaps = 23/212 (10%) Query: 80 GLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGL 139 GL G A+ + K +K L + G+P A A T ++ A I G Sbjct: 107 GLRIFGPSQRAALIEGSKAFAKELMKKYGIPTADHAAFT-------SYEEAKAYIEQKGA 159 Query: 140 PVIVKPSREGSSVGMSKVVAENALQDALRLAF------QHDEEVLIEKWLSGPEFTV--A 191 P+++K + G++ A + A +V+IE++L G EF+ Sbjct: 160 PIVIKADGLAAGKGVTVAQTVEEALAAAKAALVDGQFGTAGSQVVIEEYLEGEEFSFMAF 219 Query: 192 ILGEEILPSIRIQPSGTFYDYEA--KYLSDETQYFCPAGLEASQEANLQALVLKAWTTLG 249 + GE++ P Q YD + P + +A L+A++ A L Sbjct: 220 VNGEKVYPLAIAQDHKRAYDGDEGPNTGGMGAYSPVPQISDEMMDAALEAILRPAAKALA 279 Query: 250 CK-----GWGRIDVMLDSDGQFYLLEANTSPG 276 + G +M ++G ++E N G Sbjct: 280 AEGRPFLGVLYAGLMATANG-PKVIEFNARFG 310 >1UC8-A nrPDB Length = 280 Score = 57.3 bits (137), Expect = 9e-09, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 71/204 (34%), Gaps = 28/204 (13%) Query: 76 LELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEIS 135 L +G+P + DK + + AGLP T E + L + Sbjct: 69 LTALGIPVV-NRPEVIEACGDKWATSVALAKAGLPQPKTALATDRE-------EALRLME 120 Query: 136 ALGLPVIVKPSRE--GSSVGMSKVVAENALQDALRLA---FQHDEEVLIEKWLS--GPEF 188 A G PV++KP G + + FQH + I++++ G + Sbjct: 121 AFGYPVVLKPVIGSWGRLLAXXXXXXXXXXXXXXKEVLGGFQH-QLFYIQEYVEKPGRDI 179 Query: 189 TVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTL 248 V ++GE + +I Y A ++++ + + L +KA + Sbjct: 180 RVFVVGERAIAAI--------YRRSAHWITNTARGGQAENCP--LTEEVARLSVKAAEAV 229 Query: 249 GCKGWGRIDVMLDSDGQFYLLEAN 272 G G +D+ G + E N Sbjct: 230 G-GGVVAVDLFESERG-LLVNEVN 251 >3VPB-A nrPDB Length = 282 Score = 56.6 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 44/305 (14%), Positives = 106/305 (34%), Gaps = 55/305 (18%) Query: 17 EVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMG-FQKVFI-------ALHGRGGE 68 ++ + L E + ++ + + K++G + I AL+ Sbjct: 8 DIVRQEEKLIAKALEENKVQYDIINVAQEPLPFNKALGRYDVAIIRPVSMYRALYSS--- 64 Query: 69 DGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSD 128 +LE G+ +T + + DK+ + G+P+ + ++ Sbjct: 65 -----AVLEAAGV-HTINSSDVINVCGDKILTYSKLYREGIPIPDSII-------ALSAE 111 Query: 129 KQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEV--------LIE 180 L G P+I KP S G + + + + +H E + +++ Sbjct: 112 AALKAYEQRGFPLIDKPPIG--SWGRLVSLIRDVFEG--KTIIEHRELMGNSALKAHIVQ 167 Query: 181 KWLS--GPEFTVAILGEEILP-SIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANL 237 +++ G + +GEE+L R P + ++ P+ + + L Sbjct: 168 EYIQYKGRDIRCIAIGEELLGCYARNIPPNEWR-------ANVALGGTPSNI--EVDEKL 218 Query: 238 QALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGM------TSHSLVPMAARQAG 291 + V+KA + + + ID++ + + + E N P T+ ++ Sbjct: 219 KETVVKAVSIVH-GEFVSIDILEHPNKGYVVNELNDVPEFKGFMVATNINVAQKLVEYIK 277 Query: 292 MSFSQ 296 ++S+ Sbjct: 278 ENYSK 282 >5K2M-A nrPDB Length = 273 Score = 56.2 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 56/243 (23%), Positives = 92/243 (37%), Gaps = 45/243 (18%) Query: 75 MLELMGLPYTGSGVMASALSMDKLRSKLLWQGAG-LPVAPWVALTRAEFEKGLSDKQLAE 133 + E G+P S + + DKL + + AG +PV W A + D Sbjct: 62 LFESEGIPTVNSSRL-IFEAGDKLFA--TLRLAGKVPVPEWKAALSEGGALRVPDS---- 114 Query: 134 ISALGLPVIVKPSREGSSVGMSKVVAENALQDALR--------LAFQHDEEVLIEKWLSG 185 LG P++ KP ++KV ++L+ L L H + +EK G Sbjct: 115 ---LGYPLVSKPVFGSWGRLLAKVNDRDSLEAVLEHRKWMKNPLYGIHYFQEFVEK--PG 169 Query: 186 PEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQ--YFCPAGLEASQEANLQALVLK 243 + ++G E + +I Y Y ++++ + P + E L +K Sbjct: 170 RDIRSYVIGGEFVGAI--------YRYSNHWITNTARGGKAEPCS-DPEVEE----LSVK 216 Query: 244 AWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFS-QLVVRIL 302 AW G +G ID+ G + E N P M AAR G + +LV + Sbjct: 217 AWEAFG-EGALAIDIFESEKG-LLVNEVN--PNME----FKNAARVTGADMAGKLVEYAV 268 Query: 303 ELA 305 E+A Sbjct: 269 EVA 271 >3LP8-A nrPDB Length = 442 Score = 55.0 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 39/223 (17%), Positives = 70/223 (31%), Gaps = 24/223 (10%) Query: 80 GLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGL 139 G+ G A+ L K +K L G+P A + DK L Sbjct: 107 GILVFGPSKAAARLESSKGFTKELCMRYGIPTAKYGYFVDTNSAYKFIDKHK-------L 159 Query: 140 PVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDE------EVLIEKWLSGPEFTVAIL 193 P++VK G +A+ H + ++IE++L G E + L Sbjct: 160 PLVVKADGLAQGKGTVICHTHEEAYNAVDAMLVHHKFGEAGCAIIIEEFLEGKEISFFTL 219 Query: 194 GEEILPSIRIQPSGTFYDYEAKYLSDE---TQYFCPAGLEASQEA-NLQALVLKAWTTLG 249 + P I + + Y P + E +Q ++ + Sbjct: 220 VDGSNPVILGVAQDYKTIGDNNKGPNTGGMGSYSKPNIITQEMEHIIIQKIIYPTIKAMF 279 Query: 250 -----CKGWGRIDVMLDSDGQFYLLEANTSPGM-TSHSLVPMA 286 +G +++ + LLE N G + S++P Sbjct: 280 NMNIQFRGLLFAGIII-KKNEPKLLEYNVRFGDPETQSILPRL 321 >2CQY-A nrPDB Length = 108 Score = 54.3 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 11/105 (10%) Query: 90 ASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREG 149 +S S DK+ SKLL + A + P + +++ + +G PV++K S G Sbjct: 2 SSGSSGDKIESKLLAKKAEVNTIPG-----FDGVVKDAEEAVRIAREIGYPVMIKASAGG 56 Query: 150 SSVGMSKVVAENALQDALRLAFQH------DEEVLIEKWLSGPEF 188 GM + +D RL+ Q D+ +LIEK++ P Sbjct: 57 GGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRH 101 >5I47-A nrPDB Length = 277 Score = 48.5 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 48/256 (18%), Positives = 89/256 (34%), Gaps = 28/256 (10%) Query: 24 AAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGR-GGEDGTLQGMLELMGLP 82 ++ G +A V P ++ ++ V G E L +L G P Sbjct: 19 RLLIEAFAARGHEAVLVQPAKLALSPAAPSAGDFVAALDRGEATAERAVLAALLASGGTP 78 Query: 83 YTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVI 142 + + L D++ A +PV E A I+ +G PV+ Sbjct: 79 VV-NRAATARLLADRMALLRHLILADIPVPETRVCFGEEA-------IFAAIAEIGYPVV 130 Query: 143 VKPSREGSSVGMSKVVAENALQDALR--LAFQHDEEVLIEKWL---SGPEFTVAILGEEI 197 +K ++ V ++A + + + + VL+++++ +G + + G Sbjct: 131 LKSLTVDPGFPVALVEDQDAAEAIVEHRIMLGGERAVLVQQFIPARAGQSVRLVVAGR-S 189 Query: 198 LPSIRIQPSGTFYD-YEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRI 256 L I + G + +A Y E PA L A L + LG G + Sbjct: 190 LAGIEQRTHGGWRPGRDATY---EAYTGDPAPLTA--------LAERIIERLG-TGTYAV 237 Query: 257 DVMLDSDGQFYLLEAN 272 +V+ DG + AN Sbjct: 238 EVVETGDGPVVVGVAN 253 >1PK8-A nrPDB Length = 422 Score = 41.5 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 43/276 (15%), Positives = 89/276 (32%), Gaps = 31/276 (11%) Query: 9 LGGTSAEREVSLNSGAAVLAGLR----EGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHG 64 G E+ + A + L G + ++ V ++S+ V I H Sbjct: 131 FKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHA 190 Query: 65 R-GGEDGTLQGM---LELMGLPYTGSGVMASALSMDK----LRSKLLWQGAGLPVAPWVA 116 +G + + L+ G+P S DK + L + G P + Sbjct: 191 FSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFC-DKPWVFAQMVRLHKKLGTEEFPLID 249 Query: 117 LTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEE 176 T K + +S+ PV+VK S +G KV ++ QD + Sbjct: 250 QTFYPNHKEM-------LSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTY 302 Query: 177 VLIEKWLSGP-EFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEA 235 E ++ + V +G+ +R SG + + + + + Sbjct: 303 ATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNW------KTNTGSAMLEQIAMSDRYKL 356 Query: 236 NLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEA 271 + + + L ++ + DG+ +++E Sbjct: 357 WV-DTCSEIFGGLDICA---VEALHGKDGRDHIIEV 388 >2R84-A nrPDB Length = 334 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 68/231 (29%), Gaps = 52/231 (22%) Query: 74 GMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAE 133 ++E M +PY G+ D+ + + AG+ V E + D + Sbjct: 79 ELVENMKVPYFGNK-RVLRWESDRNLERKWLKKAGIRVP--------EVYEDPDDIEK-- 127 Query: 134 ISALGLPVIVKPSREGSSVGMSKVVAENAL----QDALRLAFQHDEEVLIEKWLSGPEFT 189 PVIVKP G + L + + D K + E+ Sbjct: 128 ------PVIVKPHGAKGGKGYFLAKDPEDFWRKAEKFLGIKRKEDL-----KNIQIQEYV 176 Query: 190 VAILGEEILPSIRIQPSGTFYDYEAKYLSD-----------------ETQYFCPAGLEAS 232 + + +++ + +Y S+ + Y + Sbjct: 177 LGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIV 236 Query: 233 QEANL-------QALVLKAWTTL--GCKGWGRIDVMLDSDGQFYLLEANTS 274 +L V+KA L G G ++ + D +F + E + Sbjct: 237 LRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISAR 287 >4FFM-A nrPDB Length = 363 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 27/78 (34%), Gaps = 20/78 (25%) Query: 87 GVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPS 146 A +S DK +SK ++ G+P R P VKP Sbjct: 94 DFEAYRISRDKKKSKDYFKSIGVPTPQ----DRPSKP----------------PYFVKPP 133 Query: 147 REGSSVGMSKVVAENALQ 164 E SSVG + + L+ Sbjct: 134 CESSSVGARIIYDDKDLE 151 >1AUX-A nrPDB Length = 311 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 42/276 (15%), Positives = 89/276 (32%), Gaps = 31/276 (11%) Query: 9 LGGTSAEREVSLNSGAAVLAGLR----EGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHG 64 G E+ + A + L G + ++ V ++S+ V I H Sbjct: 21 FKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHA 80 Query: 65 R-GGEDGTLQGM---LELMGLPYTGSGVMASALSMDK----LRSKLLWQGAGLPVAPWVA 116 +G + + L+ G+P S DK + L + G P + Sbjct: 81 FSMARNGDYRSLVIGLQYAGIPSINSLHSVYNFC-DKPWVFAQMVRLHKKLGTEEFPLIN 139 Query: 117 LTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEE 176 T K + +S+ PV+VK S +G KV ++ QD + Sbjct: 140 QTFYPNHKEM-------LSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTY 192 Query: 177 VLIEKWLSGP-EFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEA 235 E ++ + + +G+ +R SG + + + + + Sbjct: 193 ATTEPFIDAKYDVRIQKIGQNYKAYMRTSVSGNW------KTNTGSAMLEQIAMSDRYKL 246 Query: 236 NLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEA 271 + + + L ++ + DG+ +++E Sbjct: 247 WV-DTCSEIFGGLDICA---VEALHGKDGRDHIIEV 278 >3WVR-A nrPDB Length = 447 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 53/171 (30%), Gaps = 36/171 (21%) Query: 138 GLPVIVKPSREGSSVG-----------------MSKVVAENALQDALRLAFQHD------ 174 G PVI+K S G + + AL L + D Sbjct: 179 GSPVILKQDYGSGSDGNEILSRTPGLALRGARALRVLADSAALDAYLDE--RWDWLTEGG 236 Query: 175 -EEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCP----AGL 229 V++E++ G A +R+ G Y L D P A L Sbjct: 237 RHRVVVERYHPGSRAYFAEFWISDG-GVRLGGHGE-MRYRP--LPDSQVMPAPDLDQAQL 292 Query: 230 EASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSH 280 + E + L + A LG +G D ++ G+ E N ++H Sbjct: 293 DDLVEGG-RRLCV-ALHALGYRGVLSADAVVTPAGEVLFTEHNGRATGSTH 341 >1I7L-A nrPDB Length = 309 Score = 35.8 bits (81), Expect = 0.027, Method: Composition-based stats. Identities = 33/206 (16%), Positives = 67/206 (32%), Gaps = 19/206 (9%) Query: 15 EREVSLNSGAAVLAGLREGGIDAYPVDPK--EVDVTQLKSMGFQKVFIALHG-RGGEDGT 71 + ++ + L Y VD + ++S V I H E+ Sbjct: 27 DYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRPDFVLIRQHAFGMAENED 86 Query: 72 LQGML---ELMGLPYTGSGVMASALSMDK--LRSKLL--WQGAGLPVAPWVALTRAEFEK 124 + ++ + GLP + + + DK + ++++ ++ G P + T + Sbjct: 87 FRHLVIGMQYAGLPSI-NSLESIYNFCDKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHR 145 Query: 125 GLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLS 184 + PV+VK S +G KV QD + E ++ Sbjct: 146 EMLTLP-------TFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQTYATAEPFID 198 Query: 185 GP-EFTVAILGEEILPSIRIQPSGTF 209 + V +G +R SG + Sbjct: 199 AKYDIRVQKIGNNYKAYMRTSISGNW 224 >3GG2-A nrPDB Length = 450 Score = 34.6 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 34/93 (36%), Gaps = 9/93 (9%) Query: 56 QKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWV 115 +FIA+ GEDG+ + Y + +M + L+ + +PV + Sbjct: 80 DIIFIAVGTPAGEDGS-------ADMSYVLDAARSIGRAMSRY--ILIVTKSTVPVGSYR 130 Query: 116 ALTRAEFEKGLSDKQLAEISALGLPVIVKPSRE 148 + +A E+ + L + P +K Sbjct: 131 LIRKAIQEELDKREVLIDFDIASNPEFLKEGNA 163 >1QWG-A nrPDB Length = 251 Score = 33.1 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 42/103 (40%), Gaps = 11/103 (10%) Query: 81 LPYTGSGVMASALSMDKLRSKL---LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISAL 137 + + G SA+ +D+ K ++ G+ V P L + KG D+ L E L Sbjct: 39 IDFVKFGWGTSAV-IDRDVVKEKINYYKDWGIKVYPGGTLFEYAYSKGKFDEFLNECEKL 97 Query: 138 GLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIE 180 G + +GSS ++ +A++ A + VL E Sbjct: 98 GFEAV--EISDGSSD-----ISLEERNNAIKRAKDNGFMVLTE 133 >3TIN-A nrPDB Length = 380 Score = 32.3 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 22/50 (44%), Gaps = 12/50 (24%) Query: 256 IDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELA 305 D M+D + + +L+E N +P +++L I++LA Sbjct: 320 FDFMVDKNLKVWLIEVNGAPACAQ-----KL-------YAELCKGIVDLA 357 >6HQJ-A nrPDB Length = 506 Score = 31.5 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 26/78 (33%), Gaps = 7/78 (8%) Query: 198 LPSIRIQPSGTFYDYEAKYLSDETQYFC--PAGLEASQEANLQALVLKAWTTLGC--KGW 253 + + I P + L + PA QE N Q VL + + + + Sbjct: 361 VNTGSIPPESQVFPLA--KLDKAISFSINRPASSRTQQEKNAQEEVLT-FNAIKYDNRDY 417 Query: 254 GRIDVMLDSDGQFYLLEA 271 R DV L+ D E Sbjct: 418 IRFDVFLNVDNNVNANEL 435 >5CA0-F nrPDB Length = 384 Score = 31.5 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 33/97 (34%), Gaps = 16/97 (16%) Query: 191 AILGEEILPSIRIQPSGT-FYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAW---- 245 I E R + F++ +YL D LE S ++ ++ Sbjct: 244 CIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTT----LENSILLQIKHIIRSCLMCIE 299 Query: 246 -----TTLGCKG--WGRIDVMLDSDGQFYLLEANTSP 275 L + D M+D + + +L+E N +P Sbjct: 300 PAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAP 336 >4ROS-A nrPDB Length = 320 Score = 31.5 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 149 GSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLS 184 G VG+ V+ EN ++ L + F DE+ + EK ++ Sbjct: 268 GLYVGVPVVIGENGVERVLEVTFNDDEKAMFEKSVN 303 >3UFX-B nrPDB Length = 397 Score = 31.1 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 26/72 (36%), Gaps = 8/72 (11%) Query: 100 SKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGM-SKVV 158 +K + G+PV P E K ++++ G V++K G V Sbjct: 8 AKEILARYGVPVPPGKVAYTPEEAKRIAEE-------FGKRVVIKAQVHVGGRGKAGGVK 60 Query: 159 AENALQDALRLA 170 + Q+A A Sbjct: 61 LADTPQEAYEKA 72 >3E96-A nrPDB Length = 316 Score = 31.1 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 41/110 (37%), Gaps = 14/110 (12%) Query: 96 DKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMS 155 +K +K L +G+P+ P+ + + + + I G+ VIV +S Sbjct: 5 NKPLAKALETISGIPITPFRK-SDGSIDWHHYKETVDRIVDNGIDVIVPCGNTSEFYALS 63 Query: 156 KVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQP 205 L++A + +E ++ G VA +G +I + Sbjct: 64 -------LEEAKEEVRR-----TVE-YVHGRALVVAGIGYATSTAIELGN 100 >3MMZ-A nrPDB Length = 176 Score = 30.8 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 18 VSLNSGAAV-LAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGML 76 VS++ G + +A LR+ G+ + ++ V ++ + LHG +D L+ Sbjct: 38 VSVHRGDGLGIAALRKSGLTMLILSTEQNPVVAARARKLKI--PVLHGIDRKDLALKQWC 95 Query: 77 ELMGLP-----YTGSGV 88 E G+ Y G+ V Sbjct: 96 EEQGIAPERVLYVGNDV 112 >5JRY-A nrPDB Length = 485 Score = 30.4 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 4/61 (6%) Query: 109 LPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVG---MSKVVAENALQD 165 +P+ P ++ F L+ ++A A G P ++KP+ + VG + +V+AE L Sbjct: 150 VPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASR-TPVGALIIGEVLAETDLPK 208 Query: 166 A 166 Sbjct: 209 G 209 >6GVJ-A nrPDB Length = 429 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 51/144 (35%), Gaps = 21/144 (14%) Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI 201 I+K G S + +V+ E A++ + + + L +A L + S Sbjct: 148 ILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEAD---NQTLDSYRNEIAYLNKLQQHSD 204 Query: 202 RIQPSGTFYDYE--AKY---------LSDETQYFCPAGLEASQEANLQALVLKAWTTLGC 250 +I YDYE +Y + + ++ + + +L+A T+ Sbjct: 205 KIIR---LYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQ 261 Query: 251 KGWGRIDV----MLDSDGQFYLLE 270 G D+ L DG L++ Sbjct: 262 HGIVHSDLKPANFLIVDGMLKLID 285 >3HMP-A nrPDB Length = 342 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 51/144 (35%), Gaps = 21/144 (14%) Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI 201 I+K G S + +V+ E A++ + + + L +A L + S Sbjct: 60 ILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEAD---NQTLDSYRNEIAYLNKLQQHSD 116 Query: 202 RIQPSGTFYDYE--AKY---------LSDETQYFCPAGLEASQEANLQALVLKAWTTLGC 250 +I YDYE +Y + + ++ + + +L+A T+ Sbjct: 117 KIIR---LYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQ 173 Query: 251 KGWGRIDV----MLDSDGQFYLLE 270 G D+ L DG L++ Sbjct: 174 HGIVHSDLKPANFLIVDGMLKLID 197 >2ZMD-A nrPDB Length = 390 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 51/144 (35%), Gaps = 21/144 (14%) Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI 201 I+K G S + +V+ E A++ + + + L +A L + S Sbjct: 60 ILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEAD---NQTLDSYRNEIAYLNKLQQHSD 116 Query: 202 RIQPSGTFYDYE--AKY---------LSDETQYFCPAGLEASQEANLQALVLKAWTTLGC 250 +I YDYE +Y + + ++ + + +L+A T+ Sbjct: 117 KIIR---LYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQ 173 Query: 251 KGWGRIDV----MLDSDGQFYLLE 270 G D+ L DG L++ Sbjct: 174 HGIVHSDLKPANFLIVDGMLKLID 197 >4M88-A nrPDB Length = 357 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 32/89 (35%), Gaps = 14/89 (15%) Query: 112 APWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVA-----------E 160 P++ A K + L +S + IVK + G+ V A + Sbjct: 208 PPFIVAGIAALRKADVTQPLFVLSYVSAAQIVKVVGVAGARGVGIVQAFPDPNDKMLPVQ 267 Query: 161 NALQDALRLAF---QHDEEVLIEKWLSGP 186 Q A++ AF Q E +E +LS Sbjct: 268 REFQAAMKEAFPQMQEYTEFQLEGYLSAR 296 >4OB3-A nrPDB Length = 211 Score = 29.6 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 28/84 (33%), Gaps = 6/84 (7%) Query: 186 PEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDE------TQYFCPAGLEASQEANLQA 239 E T + E + + + + D A+ +E + A + + L A Sbjct: 15 KEITARVKALESMLIEQGILTTSMIDRMAEIYENEVGPHLGAKVVVKAWTDPEFKKRLLA 74 Query: 240 LVLKAWTTLGCKGWGRIDVMLDSD 263 +A LG G D+M + Sbjct: 75 DGTEACKELGIGGLQGEDMMWVEN 98 >4OB1-A nrPDB Length = 290 Score = 29.6 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 28/84 (33%), Gaps = 6/84 (7%) Query: 186 PEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDE------TQYFCPAGLEASQEANLQA 239 E T + E + + + + D A+ +E + A + + L A Sbjct: 95 KEITARVKALESMLIEQGILTTSMIDRMAEIYENEVGPHLGAKVVVKAWTDPEFKKRLLA 154 Query: 240 LVLKAWTTLGCKGWGRIDVMLDSD 263 +A LG G D+M + Sbjct: 155 DGTEACKELGIGGLQGEDMMWVEN 178 >5AP3-A nrPDB Length = 313 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 50/144 (34%), Gaps = 21/144 (14%) Query: 142 IVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSI 201 I+K G S + +V+ E A++ + + + L +A L + S Sbjct: 32 ILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEAD---NQTLDSYRNEIAYLNKLQQHSD 88 Query: 202 RIQPSGTFYDYE--AKY---------LSDETQYFCPAGLEASQEANLQALVLKAWTTLGC 250 +I YDYE +Y + ++ + + +L+A T+ Sbjct: 89 KIIR---LYDYEITDQYIYMVMECGNIDLNGWLKKKKSIDPWERKSYWKNMLEAVHTIHQ 145 Query: 251 KGWGRIDV----MLDSDGQFYLLE 270 G D+ L DG L++ Sbjct: 146 HGIVHSDLKPANFLIVDGMLKLID 169 >5J6B-A nrPDB Length = 485 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 109 LPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREG--SSVGMSKVVAENALQDA 166 +P+ P ++ F L+ ++A A G P ++KP+ ++ + +V+AE L Sbjct: 150 VPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRTPIGALIIGEVLAETDLPKG 209 >1WR2-A nrPDB Length = 238 Score = 29.2 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 7/51 (13%) Query: 94 SMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVK 144 +M + +K + + GLPV E D+ L +G PV++K Sbjct: 19 AMVEYEAKQVLKAYGLPVP-------EEKLAKTLDEALEYAKEIGYPVVLK 62 >4JHH-A nrPDB Length = 168 Score = 28.5 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 41/110 (37%), Gaps = 8/110 (7%) Query: 9 LGGTSAERE-VSLNSGAAVLAGLREGGIDAYP-----VDPKEVDVTQLKSMGFQKVFIAL 62 +G ++E E VS S + G+ E G YP K + G K + Sbjct: 6 MGVITSESEYVSSLSAEKLYRGIVEDGNIIYPKALPRFIEKAETLEGDGGPGTIKKLTFV 65 Query: 63 HGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVA 112 G G M++ YT S ALS D+ K++++ +P Sbjct: 66 -GDFGSTKQHIDMVDRENCAYTYSVYEGIALS-DQPLEKIVFEFKLVPTP 113 >3EYA-A nrPDB Length = 549 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 27/57 (47%), Gaps = 7/57 (12%) Query: 156 KVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDY 212 +V + + +AL+ AF D VL++ ++ E + P I+++ + F Y Sbjct: 500 RVEKASEVDEALQRAFSIDGPVLVDVVVAKEELAI-------PPQIKLEQAKGFSLY 549 >3Q94-A nrPDB Length = 288 Score = 28.5 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 32/99 (32%), Gaps = 16/99 (16%) Query: 96 DKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISAL----GLPVIV-------- 143 D K L + G+ + KG + AE+ + G+P+++ Sbjct: 160 DPAECKHLVEATGIDCLAPALGSVHGPYKGEPNLGFAEMEQVRDFTGVPLVLHGGTGIPT 219 Query: 144 ----KPSREGSSVGMSKVVAENALQDALRLAFQHDEEVL 178 K G+S + A+R D+EV Sbjct: 220 ADIEKAISLGTSKINVNTENQIEFTKAVREVLNKDQEVY 258 >3H9U-A nrPDB Length = 436 Score = 27.3 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 22/56 (39%) Query: 151 SVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPS 206 G VV E +AL+ A + + +L+E + V G + + + P Sbjct: 232 GFGARVVVTEVDPINALQAAMEGYQVLLVEDVVEEAHIFVTTTGNDDIITSEHFPR 287 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.138 0.358 Lambda K H 0.267 0.0423 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,035,207 Number of Sequences: 36641 Number of extensions: 417845 Number of successful extensions: 1712 Number of sequences better than 10.0: 96 Number of HSP's better than 10.0 without gapping: 96 Number of HSP's successfully gapped in prelim test: 56 Number of HSP's that attempted gapping in prelim test: 1416 Number of HSP's gapped (non-prelim): 176 length of query: 306 length of database: 10,336,785 effective HSP length: 97 effective length of query: 209 effective length of database: 6,782,608 effective search space: 1417565072 effective search space used: 1417565072 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 59 (27.3 bits)