BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07858 (339 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3PBH-A nrPDB 661 0.0 1MIR-A nrPDB 566 e-162 3CBK-A nrPDB 549 e-157 1CPJ-A nrPDB 468 e-132 2DCB-A nrPDB 452 e-127 1CSB-B nrPDB 426 e-120 1SP4-B nrPDB 353 6e-98 4I04-A nrPDB 336 7e-93 4I05-A nrPDB 324 3e-89 5OGQ-A nrPDB 323 7e-89 4HWY-A nrPDB 254 4e-68 5FPW-A nrPDB 216 1e-56 3PDF-A nrPDB 125 3e-29 1JQP-A nrPDB 112 2e-25 1NB3-A nrPDB 110 9e-25 3QJ3-A nrPDB 108 3e-24 6CZS-A nrPDB 103 1e-22 4P6E-A nrPDB 102 3e-22 2C0Y-A nrPDB 100 1e-21 2O6X-A nrPDB 99 2e-21 4BS5-A nrPDB 99 2e-21 3HWN-A nrPDB 94 9e-20 1CJL-A nrPDB 92 3e-19 3KFQ-A nrPDB 90 1e-18 3OF9-A nrPDB 90 2e-18 4YYW-A nrPDB 89 2e-18 1AEC-A nrPDB 89 3e-18 6EXO-A nrPDB 89 3e-18 1S4V-A nrPDB 89 4e-18 4QRX-A nrPDB 89 4e-18 4YYR-A nrPDB 88 7e-18 7PCK-A nrPDB 88 7e-18 4PI3-A nrPDB 87 1e-17 3QT4-A nrPDB 86 2e-17 5JT8-A nrPDB 86 2e-17 2VHS-A nrPDB 86 2e-17 2ACT-A nrPDB 86 3e-17 6MIS-A nrPDB 86 3e-17 2FO5-A nrPDB 85 5e-17 5JA7-A nrPDB 84 1e-16 3P5W-A nrPDB 83 2e-16 1DEU-A nrPDB 82 4e-16 1EF7-A nrPDB 82 4e-16 4YYQ-A nrPDB 81 8e-16 1CQD-A nrPDB 79 4e-15 2CIO-A nrPDB 78 7e-15 6BKI-A nrPDB 76 2e-14 5VPK-A nrPDB 76 3e-14 4OEL-A nrPDB 74 7e-14 5EF4-A nrPDB 74 9e-14 1M6D-A nrPDB 73 2e-13 1YAL-A nrPDB 72 3e-13 4CDF-B nrPDB 72 4e-13 1PCI-A nrPDB 71 8e-13 3BPF-A nrPDB 70 9e-13 5VCN-A nrPDB 70 9e-13 1PPO-A nrPDB 68 4e-12 1IWD-A nrPDB 68 5e-12 5A24-A nrPDB 67 1e-11 1XKG-A nrPDB 66 2e-11 2BDZ-A nrPDB 64 8e-11 4OEM-B nrPDB 64 1e-10 1ICF-A nrPDB 62 3e-10 3F75-A nrPDB 62 4e-10 3BPM-A nrPDB 61 8e-10 3U8E-A nrPDB 60 2e-09 3BCN-A nrPDB 59 2e-09 2B1M-A nrPDB 58 5e-09 1O0E-A nrPDB 58 5e-09 3IOQ-A nrPDB 57 9e-09 1GEC-E nrPDB 57 1e-08 5I4H-B nrPDB 57 1e-08 2PNS-A nrPDB 55 5e-08 5I4H-A nrPDB 49 4e-06 3CH2-X nrPDB 45 3e-05 2EKL-A nrPDB 35 0.051 1E5M-A nrPDB 32 0.33 4K7C-A nrPDB 32 0.39 3OIS-A nrPDB 30 1.5 >3PBH-A nrPDB Length = 317 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/316 (100%), Positives = 316/316 (100%) Query: 18 RSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTED 77 RSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTED Sbjct: 2 RSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTED 61 Query: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED Sbjct: 62 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 121 Query: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP Sbjct: 122 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 181 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS Sbjct: 182 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 241 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD Sbjct: 242 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 301 Query: 318 HCGIESEVVAGIPRTD 333 HCGIESEVVAGIPRTD Sbjct: 302 HCGIESEVVAGIPRTD 317 >1MIR-A nrPDB Length = 322 Score = 566 bits (1459), Expect = e-162, Method: Compositional matrix adjust. Identities = 257/320 (80%), Positives = 292/320 (91%) Query: 20 RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK 79 +PSFHPLSD+++NY+NK+NTTWQAG NFYNVD+SYLK+LCGT LGGPK P+RV F+ED+ Sbjct: 3 KPSFHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPKLPERVGFSEDIN 62 Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP SFDAREQW CPTI +IRDQGSCGS WAFGAVEA+SDRICIHTN V+VEVSAEDLL Sbjct: 63 LPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 122 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 TCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCEHHVNG+RPPCT Sbjct: 123 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCT 182 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 GEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF+V+SDF Sbjct: 183 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 242 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 L YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKILRG++HC Sbjct: 243 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRGENHC 302 Query: 320 GIESEVVAGIPRTDQYWEKI 339 GIESE+VAGIPRT QYW + Sbjct: 303 GIESEIVAGIPRTQQYWGRF 322 >3CBK-A nrPDB Length = 266 Score = 549 bits (1415), Expect = e-157, Method: Compositional matrix adjust. Identities = 263/266 (98%), Positives = 264/266 (99%) Query: 74 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEV 133 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGS WAFGAVEAISDRICIHTNAHVSVEV Sbjct: 1 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEV 60 Query: 134 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNG 193 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE HVNG Sbjct: 61 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNG 120 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 180 Query: 254 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL Sbjct: 181 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 240 Query: 314 RGQDHCGIESEVVAGIPRTDQYWEKI 339 RGQDHCGIESEVVAGIPRTDQYWEKI Sbjct: 241 RGQDHCGIESEVVAGIPRTDQYWEKI 266 >1CPJ-A nrPDB Length = 260 Score = 468 bits (1205), Expect = e-132, Method: Compositional matrix adjust. Identities = 214/259 (82%), Positives = 239/259 (92%) Query: 74 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEV 133 F+ED+ LP SFDAREQW CPTI +IRDQGSCGSCWAFGAVEA+SDRICIHTN V+VEV Sbjct: 1 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 60 Query: 134 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNG 193 SAEDLLTCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCEHHVNG Sbjct: 61 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 120 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 180 Query: 254 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 +V+SDFL YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKIL Sbjct: 181 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKIL 240 Query: 314 RGQDHCGIESEVVAGIPRT 332 RG++HCGIESE+VAGIPRT Sbjct: 241 RGENHCGIESEIVAGIPRT 259 >2DCB-A nrPDB Length = 256 Score = 452 bits (1163), Expect = e-127, Method: Compositional matrix adjust. Identities = 226/256 (88%), Positives = 243/256 (94%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP SFDAREQWP CPTIKEIRDQGSCGSCWAFGAVEAISDRICIH+N V+VEVSAED+L Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 TCCG CGDGCNGG+P+ AWNFWT+KGLVSGGLY SHVGCRPYSIPPCEHHVNGSRPPCT Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 GEGDTPKCSK CEPGYSP+YK+DKH+G +SYSV+N+EK+IMAEIYKNGPVEGAFSVYSDF Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDF 180 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 LLYKSGVYQHV+GE+MGGHAIRILGWGVENGTPYWLV NSWNTDWGDNGFFKILRGQDHC Sbjct: 181 LLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHC 240 Query: 320 GIESEVVAGIPRTDQY 335 GIESE+VAG+P T QY Sbjct: 241 GIESEIVAGMPCTHQY 256 >1CSB-B nrPDB Length = 205 Score = 426 bits (1096), Expect = e-120, Method: Compositional matrix adjust. Identities = 205/205 (100%), Positives = 205/205 (100%) Query: 129 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 188 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE Sbjct: 1 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 60 Query: 189 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 248 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP Sbjct: 61 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 120 Query: 249 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG 308 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG Sbjct: 121 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG 180 Query: 309 FFKILRGQDHCGIESEVVAGIPRTD 333 FFKILRGQDHCGIESEVVAGIPRTD Sbjct: 181 FFKILRGQDHCGIESEVVAGIPRTD 205 >1SP4-B nrPDB Length = 205 Score = 353 bits (906), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 179/204 (87%), Positives = 196/204 (96%) Query: 129 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 188 V+VEVSAED+LTCCG CGDGCNGG+P+ AWNFWT+KGLVSGGLY SHVGCRPYSIPPCE Sbjct: 2 VNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCE 61 Query: 189 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 248 HHVNGSRPPCTGEGDTPKC+K CEPGYSP+YK+DKH+G +SYSV+N+EK+IMAEIYKNGP Sbjct: 62 HHVNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGP 121 Query: 249 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG 308 VEGAFSVYSDFLLYKSGVYQHV+GE+MGGHAIRILGWGVENGTPYWLV NSWNTDWGDNG Sbjct: 122 VEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNG 181 Query: 309 FFKILRGQDHCGIESEVVAGIPRT 332 FFKILRGQDHCGIESE+VAG+P T Sbjct: 182 FFKILRGQDHCGIESEIVAGMPCT 205 >4I04-A nrPDB Length = 323 Score = 336 bits (862), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 161/313 (51%), Positives = 216/313 (69%), Gaps = 8/313 (2%) Query: 23 FHPLSDELVNYVNKR-NTTWQA--GHNFYNVDMSYLK---RLCGTFLGGPKPPQRVMFTE 76 F PLSD++++Y+N+ N W+A + F+++D + ++ R L + P Sbjct: 9 FEPLSDDIISYINEHPNAGWRAEKSNRFHSLDDARIQMGARREEPDLRRTRRPTVDHNDW 68 Query: 77 DLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAE 136 ++++P+SFD+R++WP+C +I IRDQ CGS WAFGAVEA+SDR CI + +VE+SA Sbjct: 69 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAV 128 Query: 137 DLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRP 196 DLL+CC S CG GC GG AW++W ++G+V+G E+H GC PY P CEHH G P Sbjct: 129 DLLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYP 187 Query: 197 PCTGE-GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255 PC + TP+C + C+ Y Y QDKH G +SY+V N EK I EI K GPVE F+V Sbjct: 188 PCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV 247 Query: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 Y DFL YKSG+Y+H+TGE +GGHAIRI+GWGVEN PYWL+ANSWN DWG+NG+F+I+RG Sbjct: 248 YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRG 307 Query: 316 QDHCGIESEVVAG 328 +D C IESEV AG Sbjct: 308 RDECSIESEVTAG 320 >4I05-A nrPDB Length = 285 Score = 324 bits (831), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 147/253 (58%), Positives = 187/253 (73%), Gaps = 2/253 (0%) Query: 77 DLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAE 136 ++++P+SFD+R++WP+C +I IRDQ CGSCWAFGAVEA+SDR CI + +VE+SA Sbjct: 31 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAV 90 Query: 137 DLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRP 196 DLL+CC S CG GC GG AW++W ++G+V+G E+H GC PY P CEHH G P Sbjct: 91 DLLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYP 149 Query: 197 PCTGE-GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255 PC + TP+C + C+ Y Y QDKH G +SY+V N EK I EI K GPVE F+V Sbjct: 150 PCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV 209 Query: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 Y DFL YKSG+Y+H+TGE +GGHAIRI+GWGVEN PYWL+ANSWN DWG+NG+F+I+RG Sbjct: 210 YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRG 269 Query: 316 QDHCGIESEVVAG 328 +D C IESEV AG Sbjct: 270 RDECSIESEVTAG 282 >5OGQ-A nrPDB Length = 254 Score = 323 bits (827), Expect = 7e-89, Method: Compositional matrix adjust. Identities = 147/252 (58%), Positives = 186/252 (73%), Gaps = 2/252 (0%) Query: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 +++P+SFD+R++WP+C +I IRDQ CGSCWAFGAVEA+SDR CI + +VE+SA D Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 LL+CC S CG GC GG AW++W ++G+V+G E+H GC PY P CEHH G PP Sbjct: 61 LLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPP 119 Query: 198 CTGE-GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY 256 C + TP+C + C+ Y Y QDKH G +SY+V N EK I EI K GPVE F+VY Sbjct: 120 CGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVY 179 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 DFL YKSG+Y+H+TGE +GGHAIRI+GWGVEN PYWL+ANSWN DWG+NG+F+I+RG+ Sbjct: 180 EDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGR 239 Query: 317 DHCGIESEVVAG 328 D C IESEV AG Sbjct: 240 DECSIESEVTAG 251 >4HWY-A nrPDB Length = 340 Score = 254 bits (649), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 142/316 (44%), Positives = 182/316 (57%), Gaps = 24/316 (7%) Query: 26 LSDELVNYVNKRNT-TWQAGHN--FYNVDMSYLKRLCGTFLGGPKP---PQRVMFTEDLK 79 LS V+ VN+ N W+A ++ N+ + KRL G P+R E+ + Sbjct: 32 LSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKKNNNASILPKRRFTEEEAR 91 Query: 80 --LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 LP+SFD+ E WP CPTI +I DQ +CGSCWA A A+SDR C V +SA D Sbjct: 92 APLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQ-DVHISAGD 150 Query: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSR-- 195 LL CC S CGDGCNGG P AW +++ GLVS C+PY P C HH Sbjct: 151 LLACC-SDCGDGCNGGDPDRAWAYFSSTGLVSDY-------CQPYPFPHCSHHSKSKNGY 202 Query: 196 PPCTG-EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254 PPC+ DTPKC+ C+ PT + + SY++ E D M E++ GP E AF Sbjct: 203 PPCSQFNFDTPKCNYTCD---DPTIPVVNYRSWTSYAL-QGEDDYMRELFFRGPFEVAFD 258 Query: 255 VYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 VY DF+ Y SGVY HV+G+ +GGHA+R++GWG NG PYW +ANSWNT+WG +G+F I R Sbjct: 259 VYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRR 318 Query: 315 GQDHCGIESEVVAGIP 330 G CGIE AGIP Sbjct: 319 GSSECGIEDGGSAGIP 334 >5FPW-A nrPDB Length = 321 Score = 216 bits (550), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 127/317 (40%), Positives = 174/317 (54%), Gaps = 20/317 (6%) Query: 26 LSDELVNYVNKRNT-TWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVMFTED---LK 79 L+ V+ +N+ N W+A +N N+ + KRL G ++ V FTE+ + Sbjct: 15 LTKTFVDRINQLNGGMWKAVYNGKMQNITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTE 74 Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP SFD+ E+WP CPTI+EI DQ +C + WA ISDR C + +SA LL Sbjct: 75 LPESFDSAEKWPNCPTIREIADQSACRASWAVSTASVISDRYCTVGGVQ-QLRISAAHLL 133 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHH-VNGSRPPC 198 +CC G GG+P AW ++ G+ S C+PY P CEH G++ PC Sbjct: 134 SCCKQCGGGC-KGGFPGFAWRYYVEYGIASSY-------CQPYPFPHCEHRGAQGNKTPC 185 Query: 199 TGEG-DTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 + DTPKC C P K + G +Y + + E+D E+Y NGP F VY+ Sbjct: 186 SKYNFDTPKCQATCTDKSIPLVK---YRGSATYLLLHGEEDYKRELYFNGPFVAVFYVYT 242 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 D YKSGVY+HV G+ +GG A++++GWG NGTPYW VAN+W+TDWG +G+ ILRG + Sbjct: 243 DLFAYKSGVYRHVDGDFLGGTAVKVVGWGKLNGTPYWKVANTWDTDWGMDGYLLILRGNN 302 Query: 318 HCGIESEVVAGIPRTDQ 334 C IE AG P T Q Sbjct: 303 ECNIEHLGFAGTPETSQ 319 >3PDF-A nrPDB Length = 441 Score = 125 bits (314), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 94/274 (34%), Positives = 132/274 (48%), Gaps = 40/274 (14%) Query: 66 PKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHT 125 P P + + L LP S+D R + +R+Q SCGSC++F ++ + RI I T Sbjct: 193 PAPLTAEIQQKILFLPTSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRILT 251 Query: 126 NAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIP 185 N + +S +++++C S GC GG+P K GL E C PY+ Sbjct: 252 NNSQTPILSPQEVVSC--SQYAQGCEGGFPY----LIAGKYAQDFGLVEE--ACFPYT-- 301 Query: 186 PCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYK 245 G+ PC + D C YS Y HY Y N E + E+ Sbjct: 302 -------GTDSPCKMKED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELVH 342 Query: 246 NGPVEGAFSVYSDFLLYKSGVYQHVTGEM-------MGGHAIRILGWGVEN--GTPYWLV 296 +GP+ AF VY DFL YK G+Y H TG + HA+ ++G+G ++ G YW+V Sbjct: 343 HGPMAVAFEVYDDFLHYKKGIYHH-TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIV 401 Query: 297 ANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 NSW T WG+NG+F+I RG D C IES VA P Sbjct: 402 KNSWGTGWGENGYFRIRRGTDECAIESIAVAATP 435 >1JQP-A nrPDB Length = 438 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 88/320 (27%), Positives = 142/320 (44%), Gaps = 54/320 (16%) Query: 30 LVNYVNKRNTTWQAG--HNFYNVDMSYLKRLCG----TFLGGPKPPQRVMFTEDLKLPAS 83 V +N +W A + + + L R G P P + + L LP S Sbjct: 150 FVKAINSVQKSWTATTYRRYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPES 209 Query: 84 FDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCG 143 +D R + +R+Q SCGSC++F ++ + RI I TN + +S +++++C Sbjct: 210 WDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC-- 266 Query: 144 SMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVG-----CRPYSIPPCEHHVNGSRPPC 198 S GC+GG+P + G Y G C PY+ + PC Sbjct: 267 SPYAQGCDGGFP-----------YLIAGKYAQDFGVVEENCFPYT---------ATDAPC 306 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 + + + Y ++Y + +E + E+ K+GP+ AF V+ D Sbjct: 307 KPKENCLR------------YYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDD 354 Query: 259 FLLYKSGVYQHV------TGEMMGGHAIRILGWGVE--NGTPYWLVANSWNTDWGDNGFF 310 FL Y SG+Y H + HA+ ++G+G + G YW+V NSW + WG++G+F Sbjct: 355 FLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYF 414 Query: 311 KILRGQDHCGIESEVVAGIP 330 +I RG D C IES +A IP Sbjct: 415 RIRRGTDECAIESIAMAAIP 434 >1NB3-A nrPDB Length = 220 Score = 110 bits (275), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 71/240 (29%), Positives = 114/240 (47%), Gaps = 40/240 (16%) Query: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155 + +++QGSCGSCW F A+ + I T +S+ + + L+ C + GC GG P Sbjct: 14 VSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSL--AEQQLVDCAQNFNNHGCQGGLP 71 Query: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214 ++A+ + KG++ Y P G+ D K +P Sbjct: 72 SQAFEYIRYNKGIMGEDTY-----------------------PYKGQDDHCKF----QPD 104 Query: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270 + + +D + N E+ ++ + PV AF V +DFL+Y+ G+Y H Sbjct: 105 KAIAFVKDV-----ANITMNDEEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHK 159 Query: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 T + + HA+ +G+G ENG PYW+V NSW WG NG+F I RG++ CG+ + IP Sbjct: 160 TPDKVN-HAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 218 >3QJ3-A nrPDB Length = 331 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 83/267 (31%), Positives = 122/267 (45%), Gaps = 43/267 (16%) Query: 67 KPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTN 126 K + + ++ PASFD R+Q P +++QGSCGS WAF + AI ++ I Sbjct: 103 KTREDLGLNASVRYPASFDWRDQGMVSP----VKNQGSCGSSWAFSSTGAIESQMKIANG 158 Query: 127 AHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPP 186 A VS + L+ C + GC+GG+ +A+ + + G + G PY + Sbjct: 159 AGYDSSVSEQQLVDCVPNAL--GCSGGWMNDAFTYVAQNGGI------DSEGAYPYEMAD 210 Query: 187 CEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAE-IYK 245 H Y P + GY +S +++++A+ + Sbjct: 211 GNCH------------------------YDPNQVAARLSGY--VYLSGPDENMLADMVAT 244 Query: 246 NGPVEGAFSVYSDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVENGTPYWLVANSWNTDW 304 GPV AF F Y GVY + T E HA+ I+G+G ENG YWLV NSW W Sbjct: 245 KGPVAVAFDADDPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGW 304 Query: 305 GDNGFFKILR-GQDHCGIESEVVAGIP 330 G +G+FKI R +HCGI VA +P Sbjct: 305 GLDGYFKIARNANNHCGIAG--VASVP 329 >6CZS-A nrPDB Length = 335 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 114/240 (47%), Gaps = 40/240 (16%) Query: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155 + +++QG+CGS W F A+ I I T +S+ + + L+ C GC GG P Sbjct: 129 VSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186 Query: 156 AEAWNF-WTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214 ++A+ + KG++ Y PY +G C +PG Sbjct: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219 Query: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270 + + +D + ++ + E + A N PV AF V DF++Y++G+Y H Sbjct: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274 Query: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 T + + HA+ +G+G +NG PYW+V NSW WG NG+F I RG++ CG+ + IP Sbjct: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333 >4P6E-A nrPDB Length = 230 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 79/249 (31%), Positives = 118/249 (47%), Gaps = 44/249 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+ Sbjct: 7 LPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 60 Query: 140 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 C G+ GCNGG+ A+ + KG+ S Y PY + + Sbjct: 61 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 113 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 255 T CSK E Y +D++ E N GPV G + Sbjct: 114 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 147 Query: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 + F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 148 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 207 Query: 316 Q-DHCGIES 323 + +HCGI S Sbjct: 208 KGNHCGIAS 216 >2C0Y-A nrPDB Length = 315 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 117/249 (46%), Gaps = 44/249 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D RE+ + E++ QGSCG+ WAF AV A+ ++ + T VS+ SA++L+ Sbjct: 99 LPDSVDWREK----GCVTEVKYQGSCGAAWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 152 Query: 140 TCCGSMCGD-GCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 C G+ GCNGG+ A+ + KG+ S Y PY + + Sbjct: 153 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 205 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN-GPVE-GAFSV 255 T CSK E Y +D++ E N GPV G + Sbjct: 206 AT-------CSKYTELPYG-------------------REDVLKEAVANKGPVSVGVDAR 239 Query: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 + F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R Sbjct: 240 HPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARN 299 Query: 316 Q-DHCGIES 323 + +HCGI S Sbjct: 300 KGNHCGIAS 308 >2O6X-A nrPDB Length = 310 Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 69/251 (27%), Positives = 112/251 (44%), Gaps = 44/251 (17%) Query: 90 WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149 W + + E++DQG+CGS WAF + + N S+ S + L+ C +G Sbjct: 98 WRESGYVTEVKDQGNCGSGWAFSTTGTMEGQYM--KNERTSISFSEQQLVDCSRPWGNNG 155 Query: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPP--CEHHVNGSRPPCTGEGDTPKC 207 C GG A+ + + GL + Y PY+ C ++ TG Sbjct: 156 CGGGLMENAYQYLKQFGLETESSY-------PYTAVEGQCRYNKQLGVAKVTG------- 201 Query: 208 SKICEPGYSPTYKQDKHYGYNSYSV-SNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV 266 Y+V S SE ++ + GP A V SDF++Y+SG+ Sbjct: 202 ---------------------FYTVHSGSEVELKNLVGAEGPAAVAVDVESDFMMYRSGI 240 Query: 267 YQHVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ-DHCGIESE 324 YQ T + HA+ +G+G + GT YW+V NSW WG+ G+ +++R + + CGI S Sbjct: 241 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCGIAS- 299 Query: 325 VVAGIPRTDQY 335 +A +P ++ Sbjct: 300 -LASLPMVARF 309 >4BS5-A nrPDB Length = 225 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/248 (29%), Positives = 114/248 (45%), Gaps = 41/248 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D RE+ + E++ QGSCG+CWAF AV A+ ++ + T +S+ SA++L+ Sbjct: 8 LPDTVDWREK----GCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISL--SAQNLV 61 Query: 140 TCCG--SMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 C GC GGY EA+ + ++ G E+ PY + H N Sbjct: 62 DCSNEEKYGNKGCGGGYMTEAFQY-----IIDNGGIEADAS-YPYKAMDEKCHYNSKNRA 115 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVE-GAFSVY 256 T CS+ + + E + + GPV G + + Sbjct: 116 AT-------CSRYIQLPFG------------------DEDALKEAVATKGPVSVGIDASH 150 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR-G 315 S F YKSGVY + H + ++G+G +G YWLV NSW ++GD G+ ++ R Sbjct: 151 SSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNN 210 Query: 316 QDHCGIES 323 ++HCGI S Sbjct: 211 KNHCGIAS 218 >3HWN-A nrPDB Length = 258 Score = 94.0 bits (232), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%) Query: 67 KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124 KP + +F E L + P S D RE+ P +++QG CGSCWAF A A+ ++ Sbjct: 24 KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 79 Query: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 184 T +S +S ++L+ C G +GCNGG A+ + G + ES+ PY Sbjct: 80 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY-- 129 Query: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244 E C Y+P Y G+ + EK +M + Sbjct: 130 ----------------EATEESCK------YNPKYSVANDAGF--VDIPKQEKALMKAVA 165 Query: 245 KNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVA 297 GP+ A + FL YK G+Y + E M H + ++G+G E + YWLV Sbjct: 166 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 224 Query: 298 NSWNTDWGDNGFFKILRG-QDHCGIES 323 NSW +WG G+ K+ + ++HCGI S Sbjct: 225 NSWGEEWGMGGYVKMAKDRRNHCGIAS 251 >1CJL-A nrPDB Length = 312 Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 49/271 (18%) Query: 63 LGGPKPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 120 L KP + +F E L + P S D RE+ P +++QG CGS WAF A A+ + Sbjct: 74 LQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSSWAFSATGALEGQ 129 Query: 121 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 180 + T +S +S ++L+ C G +GCNGG A+ + G + ES+ Sbjct: 130 MFRKTGRLIS--LSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDS--EESY---- 181 Query: 181 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 240 PY E C Y+P Y G+ + EK +M Sbjct: 182 PY------------------EATEESCK------YNPKYSVANDAGF--VDIPKQEKALM 215 Query: 241 AEIYKNGPVEGAFSV-YSDFLLYKSGVYQH--VTGEMMGGHAIRILGWGVE----NGTPY 293 + GP+ A + FL YK G+Y + E M H + ++G+G E +G Y Sbjct: 216 KAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDGNKY 274 Query: 294 WLVANSWNTDWGDNGFFKILRG-QDHCGIES 323 WLV NSW +WG G+ K+ + ++HCGI S Sbjct: 275 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 305 >3KFQ-A nrPDB Length = 221 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 72/251 (28%), Positives = 112/251 (44%), Gaps = 44/251 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D W + + +++Q CGSCWAF A A+ ++ T VS+ S ++L+ Sbjct: 1 LPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQNLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GCNGG+ A A+ + G + ES+ PY Sbjct: 55 DCSRPQGNQGCNGGFMARAFQYVKENGGLDS--EESY----PYVA--------------- 93 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSD 258 +IC+ Y P + G+ + EK +M + GP+ A +S Sbjct: 94 -------VDEICK--YRPENSVAQDTGF-TVVAPGKEKALMKAVATVGPISVAMDAGHSS 143 Query: 259 FLLYKSGVY-QHVTGEMMGGHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFKIL 313 F YKSG+Y + H + ++G+G E + + YWLV NSW +WG NG+ KI Sbjct: 144 FQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDNSKYWLVKNSWGPEWGSNGYVKIA 203 Query: 314 RGQ-DHCGIES 323 + + +HCGI + Sbjct: 204 KDKNNHCGIAT 214 >3OF9-A nrPDB Length = 221 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 74/253 (29%), Positives = 112/253 (44%), Gaps = 47/253 (18%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 + P S D RE+ P +++QG CGSCWAF A A+ ++ T +S +S ++L Sbjct: 1 EAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGRLIS--LSEQNL 54 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 + C G +GCNGG A+ + G + ES+ PY Sbjct: 55 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY---------------- 92 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YS 257 E C Y+P Y G+ + EK +M + GP+ A + Sbjct: 93 --EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAGHE 142 Query: 258 DFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311 FL YK G+Y + E M H + ++G+G E + YWLV NSW +WG G+ K Sbjct: 143 SFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVK 201 Query: 312 ILRG-QDHCGIES 323 + + ++HCGI S Sbjct: 202 MAKDRRNHCGIAS 214 >4YYW-A nrPDB Length = 220 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 74/252 (29%), Positives = 110/252 (43%), Gaps = 47/252 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D W + IRDQG CGSCW F + + I T+ S +S ++LL Sbjct: 1 LPETVD----WRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPS--LSEQELL 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C S GC GG+ +A+++ + +G+ S Y PY+ Sbjct: 55 DCAPSYKDLGCKGGWMDKAYDYIIKDRGITSESDY-------PYTARK------------ 95 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSY-SVSNSEKDIMAEIYKNGPVEGAFSVYS 257 G D+ K +++ +SY V +D + + N PV A S Sbjct: 96 -GACDSRKATEVVAT-------------ISSYEDVPADNEDALKKAVANQPVSVAIDASS 141 Query: 258 DFLL-YKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 + Y SGV+ G + HA+ ++G+G E+G YWLV NSW T WG+ G+ K+ R Sbjct: 142 AAVKEYSSGVFVGSCG-VANDHAVVVVGYGTESGVNYWLVRNSWGTKWGEEGYMKLERDT 200 Query: 317 DH----CGIESE 324 H CGI E Sbjct: 201 AHPAGKCGIAME 212 >1AEC-A nrPDB Length = 218 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 69/249 (27%), Positives = 111/249 (44%), Gaps = 44/249 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ D W + +I+ QG CG CWAF A+ + I T +S+ S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISL--SEQELI 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GCNGGY + + F G ++ E++ PY+ E +V+ Sbjct: 55 DCGRTQNTRGCNGGYITDGFQFIINNGGIN--TEENY----PYTAQDGECNVD------- 101 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSY-SVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 + +K+ ++Y +V + + + PV A D Sbjct: 102 -------------------LQNEKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGD 142 Query: 259 -FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--- 314 F Y SG++ G + HA+ I+G+G E G YW+V NSW+T WG+ G+ +ILR Sbjct: 143 AFKQYSSGIFTGPCGTAID-HAVTIVGYGTEGGIDYWIVKNSWDTTWGEEGYMRILRNVG 201 Query: 315 GQDHCGIES 323 G CGI + Sbjct: 202 GAGTCGIAT 210 >6EXO-A nrPDB Length = 215 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 39/250 (15%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PA+ D RE+ P ++DQG CGSCWAF + I + + N VS+ +E +L Sbjct: 2 PAAVDWREKGAVTP----VKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSL---SEQMLV 54 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C ++ GC GG A+N+ G ++ S P +G Sbjct: 55 SCDTI-DFGCGGGLMDNAFNWIVNSN--GGNVF-----------------TEASYPYVSG 94 Query: 201 EGDTPKCSKIC-EPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 G+ P+C E G + T D + E I A + +NGP+ A S F Sbjct: 95 NGEQPQCQMNGHEIGAAITDHVD---------LPQDEDAIAAYLAENGPLAIAVDATS-F 144 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 + Y G+ T E + H + ++G+ + PYW++ NSW+ WG++G+ +I +G + C Sbjct: 145 MDYNGGILTSCTSEQLD-HGVLLVGYNDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQC 203 Query: 320 GIESEVVAGI 329 + V + + Sbjct: 204 LMNQAVSSAV 213 >1S4V-A nrPDB Length = 229 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 113/259 (43%), Gaps = 45/259 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +PAS D W + + ++DQG CGSCWAF + A+ I TN VS+ +E L Sbjct: 2 VPASVD----WRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSL---SEQEL 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GCNGG A+ F ++G G + P E + Sbjct: 55 VDCDTDQNQGCNGGLMDYAFEFIKQRG-----------GITTEANYPYEAY--------D 95 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY-SD 258 G D K + +P D H +V ++++ + + N PV A SD Sbjct: 96 GTCDVSKEN-------APAVSIDGHE-----NVPENDENALLKAVANQPVSVAIDAGGSD 143 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVE-NGTPYWLVANSWNTDWGDNGFFKILRG-- 315 F Y GV+ G + H + I+G+G +GT YW V NSW +WG+ G+ ++ RG Sbjct: 144 FQFYSEGVFTGSCGTELD-HGVAIVGYGTTIDGTKYWTVKNSWGPEWGEKGYIRMERGIS 202 Query: 316 --QDHCGIESEVVAGIPRT 332 + CGI E I ++ Sbjct: 203 DKEGLCGIAMEASYPIKKS 221 >4QRX-A nrPDB Length = 363 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 84/302 (27%), Positives = 123/302 (40%), Gaps = 54/302 (17%) Query: 23 FHPLSDEL--VNYVNKRNTTWQAGHNFYNVDMS-------YLKRLCGTFLGGPKPPQRVM 73 F D L ++ NK+N ++ G N + DMS Y + G + + V+ Sbjct: 87 FEIFKDNLKYIDETNKKNNSYWLGLNVF-ADMSNDEFKEKYTGSIAGNYTTTELSYEEVL 145 Query: 74 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEV 133 D+ +P D W Q + +++QGSCGS WAF AV I I I T E Sbjct: 146 NDGDVNIPEYVD----WRQKGAVTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNL--NEY 199 Query: 134 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNG 193 S ++LL C GCNGGYP A + G+ Y PY G Sbjct: 200 SEQELLDC--DRRSYGCNGGYPWSALQLVAQYGIHYRNTY-------PYE---------G 241 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 + C P +K Y + G YS++N ++ E Sbjct: 242 VQRYCRSREKGPYAAKTDGVRQVQPYNE----GALLYSIANQPVSVVLE----------- 286 Query: 254 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 + DF LY+ G++ G + HA+ +G+ G Y L+ NSW T WG+NG+ +I Sbjct: 287 AAGKDFQLYRGGIFVGPCGNKV-DHAVAAVGY----GPNYILIRNSWGTGWGENGYIRIK 341 Query: 314 RG 315 RG Sbjct: 342 RG 343 >4YYR-A nrPDB Length = 222 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 114/258 (44%), Gaps = 43/258 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D R Q P IR+QG CGSCWAF V + I T+ S+ S + L+ Sbjct: 1 LPETVDWRIQGAVNP----IRNQGRCGSCWAFSVVVVVEGITKIVTDELPSL--SEQQLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C S GC+GG+ +A+++ + G ++ +S+ PY+ E Sbjct: 55 DCATSYKNLGCSGGWMTKAYDYIIKNGGITS---QSNY---PYTAKKGE----------- 97 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD- 258 C+K T +H N+ N+ K+ +A N PV Sbjct: 98 -------CNKDLASQIVATIDSYEHVPRNN---ENALKNAVA----NQPVSVTIEAGGRA 143 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG--- 315 F LYKSGV+ G + HA+ +G+G EN YWLV NSW T+WG+ G+ K+ R Sbjct: 144 FELYKSGVFVGSCGTKLD-HAVVAIGYGSENDVDYWLVRNSWGTNWGERGYIKLQRNVAE 202 Query: 316 -QDHCGIESEVVAGIPRT 332 CGI + + +T Sbjct: 203 PTGKCGIAMQSTYPVKKT 220 >7PCK-A nrPDB Length = 314 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 48/258 (18%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 + P S D R++ P +++QG CGSCWAF +V A+ ++ T ++ +S ++L Sbjct: 99 RAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLN--LSPQNL 152 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 + C DGC GGY A+ + + +G+ S Y PY G Sbjct: 153 VDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYV---------GQEES 194 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 C Y+PT K K GY N EK + + + GPV A Sbjct: 195 CM---------------YNPTGKAAKCRGYREIPEGN-EKALKRAVARVGPVSVAIDASL 238 Query: 257 SDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 + F Y GVY + + + HA+ +G+G++ G +W++ NSW +WG+ G+ + R Sbjct: 239 TSFQFYSKGVYYDESCNSDNL-NHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 297 Query: 315 GQDH-CGIESEVVAGIPR 331 +++ CGI + +A P+ Sbjct: 298 NKNNACGIAN--LASFPK 313 >4PI3-A nrPDB Length = 216 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/249 (25%), Positives = 108/249 (43%), Gaps = 37/249 (14%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PA+ D W + ++DQG CGSCWAF A+ + + + H +S + L++ Sbjct: 3 PAAVD----WRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLA--GHPLTNLSEQMLVS 56 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GC+GG A+ + ++ +G +Y S P +G Sbjct: 57 C--DKTDSGCSGGLMNNAFEWIVQEN--NGAVYTED-----------------SYPYASG 95 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 EG +P C+ G++ H + E I A + NGPV A S ++ Sbjct: 96 EGISPPCTT---SGHTVGATITGHV-----ELPQDEAQIAAWLAVNGPVAVAVDA-SSWM 146 Query: 261 LYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320 Y GV E + H + ++G+ PYW++ NSW T WG+ G+ +I +G + C Sbjct: 147 TYTGGVMTSCVSEQLD-HGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCL 205 Query: 321 IESEVVAGI 329 ++ E + + Sbjct: 206 VKEEASSAV 214 >3QT4-A nrPDB Length = 329 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/263 (25%), Positives = 112/263 (42%), Gaps = 48/263 (18%) Query: 66 PKPPQ--RVMFTEDLK-LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRIC 122 PK P+ R+ + K L AS D R + E++DQG CGS W+F A+ ++ Sbjct: 99 PKHPENLRMPYVSSKKPLAASVDWRSN-----AVSEVKDQGQCGSSWSFSTTGAVEGQLA 153 Query: 123 IHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPY 182 + S+ S ++L+ C S GC+GG+ A+++ G++S Y PY Sbjct: 154 LQRGRLTSL--SEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDYGIMSESAY-------PY 204 Query: 183 SIPP--CEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 240 C + S +G D P S E + Sbjct: 205 EAQGDYCRFDSSQSVTTLSGYYDLP---------------------------SGDENSLA 237 Query: 241 AEIYKNGPVEGAFSVYSDFLLYKSGV-YQHVTGEMMGGHAIRILGWGVENGTPYWLVANS 299 + + GPV A + Y G+ Y + H + ++G+G +NG YW++ NS Sbjct: 238 DAVGQAGPVAVAIDATDELQFYSGGLFYDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNS 297 Query: 300 WNTDWGDNGFFKILRGQ-DHCGI 321 W + WG++G+++ +R ++CGI Sbjct: 298 WGSGWGESGYWRQVRNYGNNCGI 320 >5JT8-A nrPDB Length = 333 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 77/259 (29%), Positives = 118/259 (45%), Gaps = 54/259 (20%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP +FD W Q + IR QGSCGSCWAF A I S+E+S ++L+ Sbjct: 113 LPQNFD----WRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQ--SIELSEQELV 166 Query: 140 TCCG-----SMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPP--CEHHVN 192 C S +GC GY EA+ + R GLV Y PY++ C+ V Sbjct: 167 DCTYNRYDPSYQCNGCGSGYSTEAFKYMIRTGLVEERNY-------PYNMRTQWCDPDVE 219 Query: 193 GSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPV--- 249 G R +G Y+Q +++ +S++D+M I ++GPV Sbjct: 220 GQRYHVSG------------------YQQLRYH--------SSDEDVMYTIQQHGPVVIY 253 Query: 250 -EGAFSVYSDFLLYKSGVYQHVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDN 307 G+ + + + +GV + V + HA+ ++GWG G YW++ NSW T WG+ Sbjct: 254 MHGSNNYFRNL---GNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWGNG 310 Query: 308 GFFKILRGQDHCGIESEVV 326 G+ + RG + GI + V Sbjct: 311 GYGYVERGHNSLGINNYVT 329 >2VHS-A nrPDB Length = 217 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/247 (28%), Positives = 108/247 (43%), Gaps = 42/247 (17%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D RE+ P +++QG CG+ +AF A A+ ++ T +S +S ++L+ Sbjct: 2 PRSVDWREKGYVTP----VKNQGQCGASYAFSATGALEGQMFRKTGRLIS--LSEQNLVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C G +GCNGG A+ + G + ES+ PY Sbjct: 56 CSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY------------------ 91 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSDF 259 E C Y+P Y G+ + EK +M + GP+ A + F Sbjct: 92 EATEESCK------YNPKYSVANDVGF--VDIPKQEKALMKAVATVGPISVAIDAGHESF 143 Query: 260 LLYKSGVY-QHVTGEMMGGHAIRILGWG-VENGTPYWLVANSWNTDWGDNGFFKILRG-Q 316 L YK G+Y HA+ ++G+G + N YWLV NSW +WG G+ K+ + + Sbjct: 144 LFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKYWLVKNSWGEEWGMGGYVKMAKDRR 203 Query: 317 DHCGIES 323 +HCGI S Sbjct: 204 NHCGIAS 210 >2ACT-A nrPDB Length = 220 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 71/252 (28%), Positives = 108/252 (42%), Gaps = 50/252 (19%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ D W + +I+ QG CG CWAF A+ + I + + +S+ S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISL--SEQELI 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GC+GGY + + F G + + + P Sbjct: 55 DCGRTQNTRGCDGGYITDGFQFIINDGGI---------------------NTEENYPYTA 93 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHY----GYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255 +GD C+ QD+ Y Y + +N A Y+ PV A Sbjct: 94 QDGD-------CDVAL-----QDQKYVTIDTYENVPYNNEWALQTAVTYQ--PVSVALDA 139 Query: 256 YSD-FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 D F Y SG++ G + HAI I+G+G E G YW+V NSW+T WG+ G+ +ILR Sbjct: 140 AGDAFKQYASGIFTGPCGTAVD-HAIVIVGYGTEGGVDYWIVKNSWDTTWGEEGYMRILR 198 Query: 315 ---GQDHCGIES 323 G CGI + Sbjct: 199 NVGGAGTCGIAT 210 >6MIS-A nrPDB Length = 215 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 64/237 (27%), Positives = 104/237 (43%), Gaps = 45/237 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +P S D W + +++QG CGSCWAF ++ + I VS +S + +L Sbjct: 1 VPQSID----WRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVS--LSEQQVL 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNF-WTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C S GC GG+ +A++F + KG+ S +Y P Sbjct: 55 DCAVSY---GCKGGWINKAYSFIISNKGVASAAIY-----------------------PY 88 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 T K + + Y Y +Y N+E+++M + N P+ A + Sbjct: 89 KAAKGTCKTNGVPNSAYITRY---------TYVQRNNERNMMYAV-SNQPIAAALDASGN 138 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVE-NGTPYWLVANSWNTDWGDNGFFKILR 314 F YK GV+ G + HAI I+G+G + +G +W+V NSW WG+ G+ ++ R Sbjct: 139 FQHYKRGVFTGPCGTRL-NHAIVIIGYGQDSSGKKFWIVRNSWGAGWGEGGYIRLAR 194 >2FO5-A nrPDB Length = 262 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 104/258 (40%), Gaps = 56/258 (21%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D W Q + ++DQG CGSCWAF V ++ I T + VS+ +E L Sbjct: 4 LPPSVD----WRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSL---SEQEL 56 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKG-LVSGGLYESHVG------CRPYSIPPCEHHVN 192 C + DGC GG A+ + G L++ Y R P H++ Sbjct: 57 IDCDTADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHID 116 Query: 193 GSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGA 252 G + D P +NSE+D +A N PV A Sbjct: 117 GHQ-------DVP---------------------------ANSEED-LARAVANQPVSVA 141 Query: 253 FSVYSD-FLLYKSGVYQHVTGEMMGGHAIRILGWGV-ENGTPYWLVANSWNTDWGDNGFF 310 F+ Y GV+ G + H + ++G+GV E+G YW V NSW WG+ G+ Sbjct: 142 VEASGKAFMFYSEGVFTGECGTELD-HGVAVVGYGVAEDGKAYWTVKNSWGPSWGEQGYI 200 Query: 311 KILRGQDH----CGIESE 324 ++ + CGI E Sbjct: 201 RVEKDSGASGGLCGIAME 218 >5JA7-A nrPDB Length = 223 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 70/258 (27%), Positives = 117/258 (45%), Gaps = 48/258 (18%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 + P S D R++ P +++QG CGS WAF +V A+ ++ T ++ +S ++L Sbjct: 8 RAPDSVDYRKKGYVTP----VKNQGQCGSSWAFSSVGALEGQLKKKTGKLLN--LSPQNL 61 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 + C DGC GGY A+ + + +G+ S Y PY G Sbjct: 62 VDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYV---------GQEES 103 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 C Y+PT K K GY N EK + + + GPV A Sbjct: 104 CM---------------YNPTGKAAKCRGYREIPEGN-EKALKRAVARVGPVSVAIDASL 147 Query: 257 SDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 + F Y GVY + + + HA+ +G+G++ G +W++ NSW +WG+ G+ + R Sbjct: 148 TSFQFYSKGVYYDESCNSDNL-NHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 206 Query: 315 GQDH-CGIESEVVAGIPR 331 +++ CGI + +A P+ Sbjct: 207 NKNNACGIAN--LASFPK 222 >3P5W-A nrPDB Length = 220 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 64/237 (27%), Positives = 104/237 (43%), Gaps = 40/237 (16%) Query: 90 WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149 W + +I+DQG CGSCWAF + A+ I T +S+ S ++L+ C + G Sbjct: 7 WRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISL--SEQELVDCGRTQNTRG 64 Query: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209 C+GG+ + + F G + + + P EG +C+ Sbjct: 65 CDGGFMTDGFQFIINNGGI---------------------NTEANYPYTAEEG---QCN- 99 Query: 210 ICEPGYSPTYKQDKHYGYNSY-SVSNSEKDIMAEIYKNGPVEGAFSVYS-DFLLYKSGVY 267 +Q+K+ ++Y +V + + + PV A +F Y SG++ Sbjct: 100 -------LDLQQEKYVSIDTYENVPYNNEWALQTAVAYQPVSVALEAAGYNFQHYSSGIF 152 Query: 268 QHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR---GQDHCGI 321 G + HA+ I+G+G E G YW+V NSW T WG+ G+ +I R G CGI Sbjct: 153 TGPCGTAVD-HAVTIVGYGTEGGIDYWIVKNSWGTTWGEEGYMRIQRNVGGVGQCGI 208 >1DEU-A nrPDB Length = 277 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 61/212 (28%), Positives = 90/212 (42%), Gaps = 27/212 (12%) Query: 105 CGSCWAFGAVEAISDRICI-HTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWT 163 CGSCWA + A++DRI I A S +S ++++ C + C GG W++ Sbjct: 63 CGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNA---GSCEGGNDLSVWDYAH 119 Query: 164 RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCS--KICEPGYSPTYKQ 221 + G+ C Y E C C+ K C + T + Sbjct: 120 QHGI-------PDETCNNYQAKDQE---------CDKFNQCGTCNEFKECHAIRNYTLWR 163 Query: 222 DKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIR 281 YG S+S EK +MAEIY NGP+ Y G+Y H + Sbjct: 164 VGDYG----SLSGREK-MMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVS 218 Query: 282 ILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 + GWG+ +GT YW+V NSW WG+ G+ +I+ Sbjct: 219 VAGWGISDGTEYWIVRNSWGEPWGERGWLRIV 250 >1EF7-A nrPDB Length = 242 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 61/212 (28%), Positives = 90/212 (42%), Gaps = 27/212 (12%) Query: 105 CGSCWAFGAVEAISDRICI-HTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWT 163 CGSCWA + A++DRI I A S +S ++++ C + C GG W++ Sbjct: 28 CGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNA---GSCEGGNDLSVWDYAH 84 Query: 164 RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCS--KICEPGYSPTYKQ 221 + G+ C Y E C C+ K C + T + Sbjct: 85 QHGI-------PDETCNNYQAKDQE---------CDKFNQCGTCNEFKECHAIRNYTLWR 128 Query: 222 DKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIR 281 YG S+S EK +MAEIY NGP+ Y G+Y H + Sbjct: 129 VGDYG----SLSGREK-MMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVS 183 Query: 282 ILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 + GWG+ +GT YW+V NSW WG+ G+ +I+ Sbjct: 184 VAGWGISDGTEYWIVRNSWGEPWGERGWLRIV 215 >4YYQ-A nrPDB Length = 217 Score = 80.9 bits (198), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 71/237 (29%), Positives = 100/237 (42%), Gaps = 43/237 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D W + IR+QG CGSCWAF AV A+ I T +S+ Sbjct: 1 LPETVD----WRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLL-- 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C S GC GG+ +A+ + + +G+ S Y P Sbjct: 55 DCAQSYKNLGCQGGWVNKAFEYIIQNRGITSQSNY-----------------------PY 91 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 TG C G + D + Y SN+E + + N PV A Sbjct: 92 TGHKGQ------CRTGLASIATIDSY----QYVPSNNENALKNAV-ANQPVSVAVEAAGR 140 Query: 259 -FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 F LYKSGV+ G + HA+ ++G+G NG YWL+ NSW T+WG+ G+ K+ R Sbjct: 141 AFQLYKSGVFTGSCGVAID-HAVVLIGYGKYNGVDYWLLRNSWGTNWGEQGYMKLQR 196 >1CQD-A nrPDB Length = 221 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 67/247 (27%), Positives = 108/247 (43%), Gaps = 46/247 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D RE P +++QG CGSCWAF V A+ I T +S+ S + L+ Sbjct: 3 LPDSIDWRENGAVVP----VKNQGGCGSCWAFSTVAAVEGINQIVTGDLISL--SEQQLV 56 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GC GG+ A+ F G ++ E++ PY Sbjct: 57 DC--TTANHGCRGGWMNPAFQFIVNNGGINS--EETY----PY----------------- 91 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS-D 258 G C+ +P D + S++ + +K + N PV D Sbjct: 92 -RGQDGICNSTVN---APVVSIDSYENVPSHNEQSLQKAVA-----NQPVSVTMDAAGRD 142 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDH 318 F LY+SG++ + + HA+ ++G+G EN +W+V NSW +WG++G+ + R ++ Sbjct: 143 FQLYRSGIFTG-SCNISANHALTVVGYGTENDKDFWIVKNSWGKNWGESGYIRAERNIEN 201 Query: 319 ----CGI 321 CGI Sbjct: 202 PDGKCGI 208 >2CIO-A nrPDB Length = 212 Score = 77.8 bits (190), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 68/228 (29%), Positives = 98/228 (42%), Gaps = 44/228 (19%) Query: 90 WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149 W Q + +++QGSCGSCWAF AV I I I T + S ++LL C G Sbjct: 7 WRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNL--NQYSEQELLDC--DRRSYG 62 Query: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209 CNGGYP A + G+ Y PY G + C P +K Sbjct: 63 CNGGYPWSALQLVAQYGIHYRNTY-------PYE---------GVQRYCRSREKGPYAAK 106 Query: 210 ICEPGYSPTYKQDKHY--GYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVY 267 + +Q + Y G YS++N ++ E + DF LY+ G++ Sbjct: 107 ------TDGVRQVQPYNEGALLYSIANQPVSVVLE-----------AAGKDFQLYRGGIF 149 Query: 268 QHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 G + HA+ +G+G Y L+ NSW T WG+NG+ +I RG Sbjct: 150 VGPCGNKV-DHAVAAVGYGPN----YILIKNSWGTGWGENGYIRIKRG 192 >6BKI-A nrPDB Length = 215 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/255 (25%), Positives = 110/255 (43%), Gaps = 44/255 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +P S D R++ P +++QG CGSCWAF + A+ ++ T +++ S ++L+ Sbjct: 1 VPDSIDYRKKGYVTP----VKNQGQCGSCWAFSSAGALEGQLKKKTGKLLAL--SPQNLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GC GGY A+ + + G + PY G C Sbjct: 55 DCVTE--NYGCGGGYMTTAFQYVQQNGGID------SEDAYPYV---------GQDESCM 97 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSD 258 Y+ K K GY V N EK + + + GP+ + + Sbjct: 98 ---------------YNAAAKAAKCRGYREIPVGN-EKALKRAVARVGPISVSIDASLAS 141 Query: 259 FLLYKSGVYQHVTGEMMG-GHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 F Y GVY + HA+ ++G+G + G+ +W++ NSW WG+ G+ + R ++ Sbjct: 142 FQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKN 201 Query: 318 H-CGIESEVVAGIPR 331 + CGI + +A P+ Sbjct: 202 NACGITN--MASFPK 214 >5VPK-A nrPDB Length = 223 Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 65/248 (26%), Positives = 97/248 (39%), Gaps = 44/248 (17%) Query: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 + +P+ D R T+ IR QG CGSCWAF V A + N S+++S ++ Sbjct: 9 VNVPSELDLRS----LRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNT--SLDLSEQE 62 Query: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 L+ C GC+G + + G+V Y P RP Sbjct: 63 LVDCASQ---HGCHGDTIPRGIEYIQQNGVVEERSY-----------PYVAREQQCRRPN 108 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKH---YGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254 G + C Y P KQ + + + +V KD+ A + +G Sbjct: 109 SQHYGISNYCQI-----YPPDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRT----- 158 Query: 255 VYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 + QH G HA+ I+G+G G YW+V NSW+T WGD+G+ Sbjct: 159 -----------IIQHDNGYQPNYHAVNIVGYGSTQGVDYWIVRNSWDTTWGDSGYGYFQA 207 Query: 315 GQDHCGIE 322 G + IE Sbjct: 208 GNNLMMIE 215 >4OEL-A nrPDB Length = 370 Score = 74.3 bits (181), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 64/206 (31%), Positives = 92/206 (44%), Gaps = 32/206 (15%) Query: 66 PKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHT 125 P P + + L LP S+D R + +R+Q SCGSC++F ++ + RI I T Sbjct: 193 PAPLTAEIQQKILHLPTSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRILT 251 Query: 126 NAHVSVEVSAEDLLTCCGSMCGDGCNGGYP-AEAWNFWTRKGLVSGGLYESHVGCRPYSI 184 N + +S +++++C S GC GG+P A + GLV C PY+ Sbjct: 252 NNSQTPILSPQEVVSC--SQYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT- 301 Query: 185 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 244 G+ PC + D C YS Y HY Y N E + E+ Sbjct: 302 --------GTDSPCKMKED-------CFRYYSSEY----HYVGGFYGGCN-EALMKLELV 341 Query: 245 KNGPVEGAFSVYSDFLLYKSGVYQHV 270 +GP+ AF VY DFL YK G+Y H Sbjct: 342 HHGPMAVAFEVYDDFLHYKKGIYHHT 367 >5EF4-A nrPDB Length = 385 Score = 73.9 bits (180), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 70/287 (24%), Positives = 114/287 (39%), Gaps = 45/287 (15%) Query: 39 TTWQAGHNFYNVDMSYLKRLCGTFLGG--PKPPQRVMFTEDLKLPASFDAREQWPQCPTI 96 T + + + N +S+ + L G+ G P + ++ K+P D W + + Sbjct: 87 TNLEFVNTYANSKISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVD----WREKNAV 142 Query: 97 KEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPA 156 +++ QG CGSCWAF AV A+ I T V+ S + L+ C M GC+GG Sbjct: 143 TDVKGQGGCGSCWAFAAVVALEGINAIRTGK--LVKFSEQQLVDC--DMTNAGCDGGLME 198 Query: 157 EAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYS 216 A+ + + G ++ P + G R C D K + Sbjct: 199 PAFTYVIKHGGIA---------------PEASYPYVGKRETC----DKAKIKDVL----- 234 Query: 217 PTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL-LYKSGVYQHVTGEMM 275 K D +V +++ + + + PV + L Y GVY G Sbjct: 235 ---KID-----GRQNVPGLDEEALRKAVAHQPVATGIQLSGHGLQFYSEGVYTGDCG-TE 285 Query: 276 GGHAIRILGWGV-ENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGI 321 H + I+G+G E G +W V NSW WG+ G+ + RG G+ Sbjct: 286 PNHGVGIVGYGENEKGIKFWTVKNSWGPTWGEKGYIHLQRGARKEGL 332 >1M6D-A nrPDB Length = 214 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 59/243 (24%), Positives = 104/243 (42%), Gaps = 40/243 (16%) Query: 90 WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149 W + +++DQG CGSCWAF + + ++ ++ +E L C M Sbjct: 7 WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQG---TLLSLSEQELLDCDKM-DKA 62 Query: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209 C GG P+ A++ K L GGL ++ G C + K Sbjct: 63 CMGGLPSNAYS--AIKNL--GGLETED-----------DYSYQGHMQSCQFSAEKAK--- 104 Query: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV--- 266 Y QD S +S +E+ + A + K GP+ A + + Y+ G+ Sbjct: 105 --------VYIQD------SVELSQNEQKLAAWLAKRGPISVAINAFG-MQFYRHGISRP 149 Query: 267 YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVV 326 + + + HA+ ++G+G + P+W + NSW TDWG+ G++ + RG CG+ + Sbjct: 150 LRPLCSPWLIDHAVLLVGYGQRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMAS 209 Query: 327 AGI 329 + + Sbjct: 210 SAV 212 >1YAL-A nrPDB Length = 218 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 65/246 (26%), Positives = 102/246 (41%), Gaps = 46/246 (18%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D R + P +++QG+CGSCWAF + + I T + E+S ++L+ Sbjct: 2 PQSIDWRAKGAVTP----VKNQGACGSCWAFSTIATVEGINKIVTGNLL--ELSEQELVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GC GGY + + G+ + +Y PY Sbjct: 56 C--DKHSYGCKGGYQTTSLQYVANNGVHTSKVY-------PY------------------ 88 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD-F 259 + KC +PG + K GY SN E + + N P+ F Sbjct: 89 QAKQYKCRATDKPG-----PKVKITGYKRVP-SNCETSFLGAL-ANQPLSVLVEAGGKPF 141 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR----G 315 LYKSGV+ G + HA+ +G+G +G Y ++ NSW +WG+ G+ ++ R Sbjct: 142 QLYKSGVFDGPCGTKLD-HAVTAVGYGTSDGKNYIIIKNSWGPNWGEKGYMRLKRQSGNS 200 Query: 316 QDHCGI 321 Q CG+ Sbjct: 201 QGTCGV 206 >4CDF-B nrPDB Length = 166 Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 59/194 (30%), Positives = 87/194 (44%), Gaps = 32/194 (16%) Query: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 L LP S+D R + +R+Q SCGSC++F ++ + RI I TN + +S ++ Sbjct: 1 LHLPTSWDWRNVH-GINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQE 59 Query: 138 LLTCCGSMCGDGCNGGYP-AEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRP 196 +++C S GC GG+P A + GLV C PY+ G+ Sbjct: 60 VVSC--SQYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT---------GTDS 101 Query: 197 PCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY 256 PC + D + Y + HY Y N E + E+ +GP+ AF VY Sbjct: 102 PCKMKEDCFR-----------YYSSEYHYVGGFYGGCN-EALMKLELVHHGPMAVAFEVY 149 Query: 257 SDFLLYKSGVYQHV 270 DFL YK G+Y H Sbjct: 150 DDFLHYKKGIYHHT 163 >1PCI-A nrPDB Length = 322 Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 84/304 (27%), Positives = 128/304 (42%), Gaps = 55/304 (18%) Query: 23 FHPLSDEL--VNYVNKRNTTWQAGHNFYNVDMS---YLKRLCGTFLGG--PKPPQRVMFT 75 F D L ++ NK+N ++ G N + D+S + ++ G+ + + Sbjct: 43 FEIFKDNLNYIDETNKKNNSYWLGLNEF-ADLSNDEFNEKYVGSLIDATIEQSYDEEFIN 101 Query: 76 EDL-KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVS 134 ED+ LP + D R++ P +R QGSCGSCWAF AV + I T VE+S Sbjct: 102 EDIVNLPENVDWRKKGAVTP----VRHQGSCGSCWAFSAVATVEGINKIRTGKL--VELS 155 Query: 135 AEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKG--LVSGGLYESHVG-CRPYSIPPCEHHV 191 ++L+ C GC GGYP A + + G L S Y++ G CR V Sbjct: 156 EQELVDC--ERRSHGCKGGYPPYALEYVAKNGIHLRSKYPYKAKQGTCRA-------KQV 206 Query: 192 NGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEG 251 G +G G +P N+E +++ I K Sbjct: 207 GGPIVKTSGVGR-------VQP--------------------NNEGNLLNAIAKQPVSVV 239 Query: 252 AFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFK 311 S F LYK G+++ G + G A+ +G+G G Y L+ NSW T WG+ G+ + Sbjct: 240 VESKGRPFQLYKGGIFEGPCGTKVDG-AVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIR 298 Query: 312 ILRG 315 I R Sbjct: 299 IKRA 302 >3BPF-A nrPDB Length = 241 Score = 70.5 bits (171), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 59/241 (24%), Positives = 101/241 (41%), Gaps = 49/241 (20%) Query: 83 SFD-AREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTC 141 +FD A W + ++DQ +CGSCWAF ++ ++ + I N +++ S ++L+ C Sbjct: 16 NFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITL--SEQELVDC 73 Query: 142 CGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGE 201 S GCNGG A+ G I P + Sbjct: 74 --SFKNYGCNGGLINNAFEDMIELG----------------GICP--------------D 101 Query: 202 GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLL 261 GD P S P + + YG +Y +S + + + GP+ + +V DF Sbjct: 102 GDYPYVSD--APNLCNIDRCTEKYGIKNY-LSVPDNKLKEALRFLGPISISVAVSDDFAF 158 Query: 262 YKSGVYQHVTGEMMGGHAIRILGWGVENGTP----------YWLVANSWNTDWGDNGFFK 311 YK G++ G+ + HA+ ++G+G++ Y+++ NSW WG+ GF Sbjct: 159 YKEGIFDGECGDQLN-HAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFIN 217 Query: 312 I 312 I Sbjct: 218 I 218 >5VCN-A nrPDB Length = 222 Score = 70.5 bits (171), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 61/233 (26%), Positives = 88/233 (37%), Gaps = 46/233 (19%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PA D R Q T+ IR QG CGSCWAF V A + N S++++ ++L+ Sbjct: 11 PAEIDLR----QMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQ--SLDLAEQELVD 64 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYE---SHVGCRPYSIPPCEHHVNGSRPP 197 C GC+G + G+V Y CR RP Sbjct: 65 CASQ---HGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCR--------------RPN 107 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 G + C Y P +N ++ +A+ + V Sbjct: 108 AQRFGISNYCQI-----YPPN--------------ANKIREALAQTHSAIAVIIGIKDLD 148 Query: 258 DFLLYK-SGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGF 309 F Y + Q G HA+ I+G+ G YW+V NSW+T+WGDNG+ Sbjct: 149 AFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGY 201 >1PPO-A nrPDB Length = 216 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 101/238 (42%), Gaps = 46/238 (19%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D R++ P +R QGSCGSCWAF AV + I T VE+S ++L+ Sbjct: 1 LPENVDWRKKGAVTP----VRHQGSCGSCWAFSAVATVEGINKIRTGKL--VELSEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKG--LVSGGLYESHVG-CRPYSIPPCEHHVNGSRP 196 C GC GGYP A + + G L S Y++ G CR V G Sbjct: 55 DC--ERRSHGCKGGYPPYALEYVAKNGIHLRSKYPYKAKQGTCR-------AKQVGGPIV 105 Query: 197 PCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY 256 +G G +P N+E +++ I K S Sbjct: 106 KTSGVGRV-------QP--------------------NNEGNLLNAIAKQPVSVVVESKG 138 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 F LYK G+++ G + HA+ +G+G G Y L+ NSW T WG+ G+ +I R Sbjct: 139 RPFQLYKGGIFEGPCGTKV-DHAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKR 195 >1IWD-A nrPDB Length = 215 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 59/235 (25%), Positives = 99/235 (42%), Gaps = 41/235 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ D W + I++Q CGSCWAF AV A+ I T +S +S ++L+ Sbjct: 1 LPSFVD----WRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLIS--LSEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GCNGG+ A+ + +++ G ++ PYS V GS P Sbjct: 55 DC--DTASHGCNGGWMNNAFQY-----IITNGGIDTQQN-YPYSA------VQGSCKPY- 99 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 + + G+ + N+E + + + + + F Sbjct: 100 ------RLRVVSINGFQRVTR-------------NNESALQSAVASQPVSVTVEAAGAPF 140 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 Y SG++ G H + I+G+G ++G YW+V NSW +WG+ G+ + R Sbjct: 141 QHYSSGIFTGPCGTAQ-NHGVVIVGYGTQSGKNYWIVRNSWGQNWGNQGYIWMER 194 >5A24-A nrPDB Length = 222 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 68/255 (26%), Positives = 103/255 (40%), Gaps = 47/255 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +PA+ D W + +++Q CG CWAF AV AI I T S+ S E ++ Sbjct: 1 VPAAVD----WRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSL--SEEQIV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C + GCNGG P A+ + +G+ + Y PY+ Sbjct: 55 DCDTNGNDKGCNGGTPDGAFQYVVNNQGIDTESDY-------PYT--------------- 92 Query: 199 TGEGDTPKCSKIC-EPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 G G CS +P S T QD V + + + + P+ A Sbjct: 93 AGGGSPGTCSASSYQPAASITGYQD---------VPANNEQALQQAAATQPISVAIDASD 143 Query: 258 -DFLLYKSGVYQHVTGEMMGGHAIRILGWGVE--NGTPYWLVANSWNTDWGDNGFFKILR 314 F Y SG+Y + HA+ ++G+G + +G YW+V NSW T WG G+ + Sbjct: 144 PSFQSYSSGIYSGPCNTNLD-HAVTVVGYGTDPNSGNSYWIVKNSWGTSWGQEGYIWMQM 202 Query: 315 GQDH----CGIESEV 325 G + CGI + Sbjct: 203 GLNAPYGVCGIAMQA 217 >1XKG-A nrPDB Length = 312 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 59/233 (25%), Positives = 88/233 (37%), Gaps = 46/233 (19%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PA D R Q T+ IR QG CGS WAF V A + + S++++ ++L+ Sbjct: 91 PAEIDLR----QMRTVTPIRMQGGCGSAWAFSGVAATESAYLAYRDQ--SLDLAEQELVD 144 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYE---SHVGCRPYSIPPCEHHVNGSRPP 197 C GC+G + G+V Y CR RP Sbjct: 145 CASQH---GCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCR--------------RPN 187 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 G + C +I P +N ++ +A+ + V Sbjct: 188 AQRFGISNYC-QIYPPN------------------ANKIREALAQTHSAIAVIIGIKDLD 228 Query: 258 DFLLYK-SGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGF 309 F Y + Q G HA+ I+G+ G YW+V NSW+T+WGDNG+ Sbjct: 229 AFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGY 281 >2BDZ-A nrPDB Length = 214 Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 99/250 (39%), Gaps = 58/250 (23%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D RE+ P +++Q CGSCWAF V I I T +S +S ++LL Sbjct: 2 PESIDWREKGAVTP----VKNQNPCGSCWAFSTVATIEGINKIITGQLIS--LSEQELLD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GC+GGY + + G+ + Y PY + P Sbjct: 56 C--ERRSHGCDGGYQTTSLQYVVDNGVHTEREY-------PYEKKQGRCRAKDKKGP--- 103 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD-- 258 K+ GY Y +N E ++ I N PV SV +D Sbjct: 104 --------KVYITGY-------------KYVPANDEISLIQAI-ANQPV----SVVTDSR 137 Query: 259 ---FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 F YK G+Y+ G HA+ +G+ G Y L+ NSW +WG+ G+ +I R Sbjct: 138 GRGFQFYKGGIYEGPCGTNT-DHAVTAVGY----GKTYLLLKNSWGPNWGEKGYIRIKRA 192 Query: 316 ----QDHCGI 321 + CG+ Sbjct: 193 SGRSKGTCGV 202 >4OEM-B nrPDB Length = 70 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 28/58 (48%), Positives = 39/58 (67%), Gaps = 2/58 (3%) Query: 275 MGGHAIRILGWGVEN--GTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 + HA+ ++G+G ++ G YW+V NSW T WG+NG+F+I RG D C IES VA P Sbjct: 8 LTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATP 65 >1ICF-A nrPDB Length = 175 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 58/212 (27%), Positives = 89/212 (41%), Gaps = 42/212 (19%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D RE+ P +++QG CGSCWAF A A+ ++ T +S +S ++L+ Sbjct: 2 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGRLIS--LSEQNLVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C G +GCNGG A+ + G + ES+ PY Sbjct: 56 CSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--EESY----PY------------------ 91 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSDF 259 E C Y+P Y G+ + EK +M + GP+ A + F Sbjct: 92 EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAGHESF 143 Query: 260 LLYKSGVY--QHVTGEMMGGHAIRILGWGVEN 289 L YK G+Y + E M H + ++G+G E+ Sbjct: 144 LFYKEGIYFEPDCSSEDM-DHGVLVVGYGFES 174 >3F75-A nrPDB Length = 224 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 63/250 (25%), Positives = 105/250 (42%), Gaps = 45/250 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ A W + ++DQ CGSCWAF A+ C T VS +S ++L+ Sbjct: 3 LPSELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVS--LSEQELM 60 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + C+GG +A+ + L SGG+ C + P Sbjct: 61 DCSRAEGNQSCSGGEMNDAFQYV----LDSGGI------CSEDAYPYLARDE-------- 102 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD- 258 E C K+ K G+ SE + A + K+ PV + ++ +D Sbjct: 103 -ECRAQSCEKVV-----------KILGFKDVP-RRSEAAMKAALAKS-PV--SIAIEADQ 146 Query: 259 --FLLYKSGVYQHVTGEMMGGHAIRILGWGV--ENGTPYWLVANSWNTDWGDNGFFKIL- 313 F Y GV+ G + H + ++G+G E+ +W++ NSW T WG +G+ + Sbjct: 147 MPFQFYHEGVFDASCGTDL-DHGVLLVGYGTDKESKKDFWIMKNSWGTGWGRDGYMYMAM 205 Query: 314 -RGQD-HCGI 321 +G++ CG+ Sbjct: 206 HKGEEGQCGL 215 >3BPM-A nrPDB Length = 243 Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 56/234 (23%), Positives = 97/234 (41%), Gaps = 48/234 (20%) Query: 89 QWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGD 148 W + ++DQ CGSCWAF +V ++ + I A S ++L+ C S+ + Sbjct: 25 DWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLF--SEQELVDC--SVKNN 80 Query: 149 GCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCS 208 GC GGY A++ + GGL C+ + D P S Sbjct: 81 GCYGGYITNAFD----DMIDLGGL-------------------------CS-QDDYPYVS 110 Query: 209 KICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ 268 + P + ++ Y SY VS + + GP+ + + DF Y+ G Y Sbjct: 111 NL--PETCNLKRCNERYTIKSY-VSIPDDKFKEALRYLGPISISIAASDDFAFYRGGFYD 167 Query: 269 HVTGEMMGGHAIRILGWGVEN----------GTPYWLVANSWNTDWGDNGFFKI 312 G HA+ ++G+G+++ Y+++ NSW +DWG+ G+ + Sbjct: 168 GECG-AAPNHAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINL 220 >3U8E-A nrPDB Length = 222 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 69/254 (27%), Positives = 109/254 (42%), Gaps = 54/254 (21%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PAS D W + + ++DQG+CG CWAFGA AI I T +S VS + ++ Sbjct: 2 PASID----WRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLIS--VSEQQIVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNF-WTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GG +A+ + T G+ S Y PY+ V+G T Sbjct: 56 C--DTXXXXXXGGDADDAFRWVITNGGIASDANY-------PYT------GVDG-----T 95 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 + + P ++I GY+ +V NS ++ + K ++ + F Sbjct: 96 CDLNKPIAARI--DGYT--------------NVPNSSSALLDAVAKQPVSVNIYTSSTSF 139 Query: 260 LLYKS-GVYQHVT---GEMMGGHAIRILGWGVENGT--PYWLVANSWNTDWGDNGFFKIL 313 LY G++ + H + I+G+G NGT YW+V NSW T+WG +G+ I Sbjct: 140 QLYTGPGIFAGSSCSDDPATVDHTVLIVGYG-SNGTNADYWIVKNSWGTEWGIDGYILIR 198 Query: 314 RGQDH----CGIES 323 R + C I++ Sbjct: 199 RNTNRPDGVCAIDA 212 >3BCN-A nrPDB Length = 209 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 64/246 (26%), Positives = 99/246 (40%), Gaps = 52/246 (21%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D R + P +++QG CGSCWAF V + I T +S +S + L+ Sbjct: 1 LPEHVDWRAKGAVIP----LKNQGKCGSCWAFSTVTTVESINQIRTGNLIS--LSEQQLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI--PPCEHHVNGSRPP 197 C S GC GGY A+ + +++ G ++ PY PC R Sbjct: 55 DC--SKKNHGCKGGYFDRAYQY-----IIANGGIDTEAN-YPYKAFQGPCRAAKKVVR-- 104 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 G P+C++ N+ K+ +A V + Sbjct: 105 IDGCKGVPQCNE------------------------NALKNAVAS---QPSVVAIDASSK 137 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--G 315 F YK G++ G + H + I+G+G + YW+V NSW WG+ G+ ++ R G Sbjct: 138 QFQHYKGGIFTGPCGTKL-NHGVVIVGYGKD----YWIVRNSWGRHWGEQGYTRMKRVGG 192 Query: 316 QDHCGI 321 CGI Sbjct: 193 CGLCGI 198 >2B1M-A nrPDB Length = 246 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 61/238 (25%), Positives = 91/238 (38%), Gaps = 40/238 (16%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S+D W + I +++ QG CGS WAF A AI I T VS+ S ++L+ Sbjct: 3 PESWD----WSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSL--SEQELID 56 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRK--GLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C +GC G+ +++ W K G+ S Y PY + N + Sbjct: 57 CVDE--SEGCYNGWHYQSFE-WVVKHGGIASEADY-------PYKARDGKCKANEIQDKV 106 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 T + + SVS KD Sbjct: 107 TIDNYGVQILSNESTESEAESSLQSFVLEQPISVSIDAKD-------------------- 146 Query: 259 FLLYKSGVYQ--HVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 F Y G+Y + + H + I+G+G E+G YW+ NSW DWG +G+ +I R Sbjct: 147 FHFYSGGIYDGGNCSSPYGINHFVLIVGYGSEDGVDYWIAKNSWGEDWGIDGYIRIQR 204 >1O0E-A nrPDB Length = 208 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 60/244 (24%), Positives = 92/244 (37%), Gaps = 48/244 (19%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D R++ P +++QGSCGSCWAF V + I T +S+ S ++L+ Sbjct: 1 LPEQIDWRKKGAVTP----VKNQGSCGSCWAFSTVSTVESINQIRTGNLISL--SEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GC GG A+ + G + + P Sbjct: 55 DC--DKKNHGCLGGAFVFAYQYIINNGGID---------------------TQANYPYKA 91 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 +G SK+ GYN N E + + + + F Sbjct: 92 VQGPCQAASKVVSID-----------GYNGVPFCN-EXALKQAVAVQPSTVAIDASSAQF 139 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--GQD 317 Y SG++ G + H + I+G+ YW+V NSW WG+ G+ ++LR G Sbjct: 140 QQYSSGIFSGPCGTKLN-HGVTIVGYQAN----YWIVRNSWGRYWGEKGYIRMLRVGGCG 194 Query: 318 HCGI 321 CGI Sbjct: 195 LCGI 198 >3IOQ-A nrPDB Length = 213 Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 70/252 (27%), Positives = 102/252 (40%), Gaps = 50/252 (19%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +P S D W Q + +R+QG CGSCW F +V A+ I T +S +S ++LL Sbjct: 1 IPTSID----WRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLS--LSEQELL 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GC GG+P A + G+ Y PY Sbjct: 55 DC--ERRSYGCRGGFPLYALQYVANSGIHLRQYY-------PY----------------- 88 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD- 258 EG +C G P K D N+E+ ++ I PV Sbjct: 89 -EGVQRQCRASQAKG--PKVKTDGV----GRVPRNNEQALIQRIAIQ-PVSIVVEAKGRA 140 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG--- 315 F Y+ G++ G + HA+ +G+G + Y L+ NSW T WG+ G+ +I RG Sbjct: 141 FQNYRGGIFAGPCGTSI-DHAVAAVGYGND----YILIKNSWGTGWGEGGYIRIKRGSGN 195 Query: 316 -QDHCGIESEVV 326 Q CG+ S+ V Sbjct: 196 PQGACGVLSDSV 207 >1GEC-E nrPDB Length = 216 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 67/259 (25%), Positives = 100/259 (38%), Gaps = 50/259 (19%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D R + P ++ QG C SCWAF V + I T V E+S ++L+ Sbjct: 1 LPESVDWRAKGAVTP----VKHQGYCESCWAFSTVATVEGINKIKTGNLV--ELSEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLY---ESHVGCRPYSIPPCEHHVNGSRP 196 C + GCN GY + + + + G+ Y CR + V G + Sbjct: 55 DC--DLQSYGCNRGYQSTSLQYVAQNGIHLRAKYPYIAKQQTCRA-------NQVGGPKV 105 Query: 197 PCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY 256 G G SN+E ++ I S Sbjct: 106 KTNGVGRVQ---------------------------SNNEGSLLNAIAHQPVSVVVESAG 138 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 DF YK G+++ G + HA+ +G+G G Y L+ NSW WG+NG+ +I R Sbjct: 139 RDFQNYKGGIFEGSCGTKVD-HAVTAVGYGKSGGKGYILIKNSWGPGWGENGYIRIRRAS 197 Query: 317 DHCGIESEVVAGIPRTDQY 335 + S V G+ R+ Y Sbjct: 198 GN----SPGVCGVYRSSYY 212 >5I4H-B nrPDB Length = 112 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 34/100 (34%), Positives = 52/100 (52%), Gaps = 9/100 (9%) Query: 232 VSNSEKDIMAEIYKNGPVEGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVE 288 + EK +M + GP+ A + FL YK G+Y + E M H + ++G+G E Sbjct: 7 IPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMD-HGVLVVGYGFE 65 Query: 289 ----NGTPYWLVANSWNTDWGDNGFFKILRG-QDHCGIES 323 + YWLV NSW +WG G+ K+ + ++HCGI S Sbjct: 66 STESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 105 >2PNS-A nrPDB Length = 208 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 60/246 (24%), Positives = 93/246 (37%), Gaps = 52/246 (21%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D R++ P +++QG CGSCWAF V + I T +S+ S + L+ Sbjct: 1 LPEQIDWRKKGAVTP----VKNQGKCGSCWAFSTVSTVESINQIRTGNLISL--SEQQLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIP--PCEHHVNGSRPP 197 C + GC GG A+ + ++ G ++ PY PC R Sbjct: 55 DC--NKKNHGCKGGAFVYAYQY-----IIDNGGIDTEAN-YPYKAVQGPCRAAKKVVR-- 104 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 G P C+ E + + V + Sbjct: 105 IDGYKGVPHCN---------------------------ENALKKAVASQPSVVAIDASSK 137 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--G 315 F YKSG++ G + H + I+G+ + YW+V NSW WG+ G+ ++ R G Sbjct: 138 QFQHYKSGIFSGPCGTKLN-HGVVIVGYWKD----YWIVRNSWGRYWGEQGYIRMKRVGG 192 Query: 316 QDHCGI 321 CGI Sbjct: 193 CGLCGI 198 >5I4H-A nrPDB Length = 106 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 6/88 (6%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 + P S D RE+ P +++QG CGS WAF A A+ ++ T +S +S ++L Sbjct: 1 EAPRSVDWREKGYVTP----VKNQGQCGSSWAFSATGALEGQMFRKTGRLIS--LSEQNL 54 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKG 166 + C G +GCNGG A+ + G Sbjct: 55 VDCSGPQGNEGCNGGLMDYAFQYVQDNG 82 >3CH2-X nrPDB Length = 265 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 58/253 (22%), Positives = 96/253 (37%), Gaps = 48/253 (18%) Query: 92 QCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCN 151 C + ++ DQG+C + W F + + C+ + ++SA + C D C+ Sbjct: 17 NCISNLQVEDQGNCDTSWIFASKYHLETIRCM--KGYEPTKISALYVANCYKGEHKDRCD 74 Query: 152 -GGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI-------PPCEHH----------VNG 193 G P E G + ES+ PY+ P E H ++ Sbjct: 75 EGSSPMEFLQIIEDYGFLPA---ESNY---PYNYVKVGEQCPKVEDHWMNLWDNGKILHN 128 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 P + +G GY+ + H +++ K I E+ G V Sbjct: 129 KNEPNSLDG----------KGYTAYESERFHDNMDAFV-----KIIKTEVMNKGSVIAYI 173 Query: 254 SVYSDFLLYKSGV-YQHVTGEMMGGHAIRILGWGVENGTP-----YWLVANSWNTDWGDN 307 + SG Q++ G+ HA+ I+G+G + YW+V NSW WGD Sbjct: 174 KAENVMGYEFSGKKVQNLCGDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDE 233 Query: 308 GFFKI-LRGQDHC 319 G+FK+ + G HC Sbjct: 234 GYFKVDMYGPTHC 246 >2EKL-A nrPDB Length = 313 Score = 35.0 bits (79), Expect = 0.051, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Query: 249 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 300 + A +Y+ L KSG+++ + G + G I I+G+G GT ++AN+ Sbjct: 114 IAAARKMYTSMALAKSGIFKKIEGLELAGKTIGIVGFG-RIGTKVGIIANAM 164 >1E5M-A nrPDB Length = 416 Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 16/84 (19%) Query: 26 LSDELVNYVNKRNTTWQA-------------GHNFYNVDMSYLKRLCGTFLGGP---KPP 69 L E+V+Y+N T+ A G++ YN+ +S K + G LGG + Sbjct: 296 LKPEMVSYINAHGTSTPANDVTETRAIKQALGNHAYNIAVSSTKSMTGHLLGGSGGIEAV 355 Query: 70 QRVMFTEDLKLPASFDAREQWPQC 93 VM + K+P + + P+C Sbjct: 356 ATVMAIAEDKVPPTINLENPDPEC 379 >4K7C-A nrPDB Length = 446 Score = 32.0 bits (71), Expect = 0.39, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPY-WLVANSWNTDWGDNGFF 310 +DF + K+ + GE + HA+ + G + +G P W V NSW G+ G+F Sbjct: 345 TDFTMTKAERLDY--GESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 >3OIS-A nrPDB Length = 291 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 16/123 (13%) Query: 202 GDTPKCSKICE--PGYSPT-------YKQDKHYGYNSYS-VSNSEKDIMAEIYKNGPVEG 251 GDTP + E PG + YK ++Y YS V+ + A + P Sbjct: 147 GDTPADPRTEEFPPGAPASKKPSDQCYKDAQNYKITEYSRVAQDIDHLKACLAVGSPFVF 206 Query: 252 AFSVYSDFLLYKSGVYQ----HVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDN 307 FSVY+ ++ S + + GGHA+ +G+ ++ ++ + NSW + G++ Sbjct: 207 GFSVYNSWVGNNSLPVRIPLPTKNDTLEGGHAVLCVGY--DDEIRHFRIRNSWGNNVGED 264 Query: 308 GFF 310 G+F Sbjct: 265 GYF 267 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3PBH-A nrPDB 447 e-126 1MIR-A nrPDB 432 e-122 3CBK-A nrPDB 369 e-103 1CPJ-A nrPDB 349 1e-96 4I04-A nrPDB 343 7e-95 2DCB-A nrPDB 323 8e-89 4I05-A nrPDB 318 2e-87 5OGQ-A nrPDB 301 3e-82 4HWY-A nrPDB 292 2e-79 1CSB-B nrPDB 276 1e-74 5FPW-A nrPDB 274 4e-74 1JQP-A nrPDB 273 9e-74 3PDF-A nrPDB 270 7e-73 4QRX-A nrPDB 260 4e-70 1PCI-A nrPDB 252 1e-67 5EF4-A nrPDB 248 4e-66 1CJL-A nrPDB 245 3e-65 3HWN-A nrPDB 244 4e-65 1S4V-A nrPDB 243 8e-65 6CZS-A nrPDB 241 3e-64 1SP4-B nrPDB 241 3e-64 3QJ3-A nrPDB 239 1e-63 1NB3-A nrPDB 239 1e-63 4YYR-A nrPDB 237 6e-63 3P5W-A nrPDB 236 1e-62 2C0Y-A nrPDB 235 2e-62 4BS5-A nrPDB 235 2e-62 3OF9-A nrPDB 234 4e-62 4P6E-A nrPDB 232 1e-61 3KFQ-A nrPDB 231 4e-61 2FO5-A nrPDB 230 5e-61 2O6X-A nrPDB 230 8e-61 7PCK-A nrPDB 228 2e-60 1AEC-A nrPDB 227 4e-60 3QT4-A nrPDB 227 5e-60 4YYW-A nrPDB 225 2e-59 3BCN-A nrPDB 223 1e-58 2VHS-A nrPDB 223 1e-58 1CQD-A nrPDB 221 2e-58 2ACT-A nrPDB 221 3e-58 2PNS-A nrPDB 221 4e-58 1YAL-A nrPDB 220 5e-58 1IWD-A nrPDB 218 4e-57 5JA7-A nrPDB 217 4e-57 1O0E-A nrPDB 216 1e-56 6BKI-A nrPDB 215 2e-56 1PPO-A nrPDB 213 7e-56 3F75-A nrPDB 213 1e-55 6MIS-A nrPDB 213 1e-55 6EXO-A nrPDB 211 2e-55 2BDZ-A nrPDB 211 4e-55 2CIO-A nrPDB 210 6e-55 4YYQ-A nrPDB 207 5e-54 4PI3-A nrPDB 202 2e-52 1GEC-E nrPDB 201 3e-52 2B1M-A nrPDB 201 4e-52 5A24-A nrPDB 200 7e-52 5VPK-A nrPDB 198 2e-51 3BPF-A nrPDB 195 2e-50 1XKG-A nrPDB 190 9e-49 3IOQ-A nrPDB 190 1e-48 5VCN-A nrPDB 187 5e-48 3BPM-A nrPDB 184 6e-47 1ICF-A nrPDB 183 7e-47 1M6D-A nrPDB 183 1e-46 4OEL-A nrPDB 183 1e-46 3U8E-A nrPDB 182 2e-46 1DEU-A nrPDB 174 6e-44 1EF7-A nrPDB 167 7e-42 5JT8-A nrPDB 165 2e-41 3CH2-X nrPDB 158 2e-39 4CDF-B nrPDB 153 9e-38 5I4H-A nrPDB 125 4e-29 5I4H-B nrPDB 124 8e-29 4OEM-B nrPDB 99 3e-21 Sequences not found previously or not previously below threshold: 4CI7-A nrPDB 69 4e-12 4D59-A nrPDB 68 9e-12 3OIS-A nrPDB 60 1e-09 4K7C-A nrPDB 44 6e-05 5WDK-A nrPDB 38 0.006 2CB5-A nrPDB 36 0.030 2EKL-A nrPDB 31 0.64 3N7B-A nrPDB 31 0.88 2Z51-A nrPDB 29 2.1 5O4O-C nrPDB 28 4.7 3P11-A nrPDB 28 4.7 5E9F-A nrPDB 28 4.8 5DDC-A nrPDB 28 6.2 2CBT-A nrPDB 27 9.7 >3PBH-A nrPDB Length = 317 Score = 447 bits (1149), Expect = e-126, Method: Composition-based stats. Identities = 316/316 (100%), Positives = 316/316 (100%) Query: 18 RSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTED 77 RSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTED Sbjct: 2 RSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTED 61 Query: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED Sbjct: 62 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 121 Query: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP Sbjct: 122 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 181 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS Sbjct: 182 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 241 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD Sbjct: 242 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 301 Query: 318 HCGIESEVVAGIPRTD 333 HCGIESEVVAGIPRTD Sbjct: 302 HCGIESEVVAGIPRTD 317 >1MIR-A nrPDB Length = 322 Score = 432 bits (1111), Expect = e-122, Method: Composition-based stats. Identities = 257/320 (80%), Positives = 292/320 (91%) Query: 20 RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLK 79 +PSFHPLSD+++NY+NK+NTTWQAG NFYNVD+SYLK+LCGT LGGPK P+RV F+ED+ Sbjct: 3 KPSFHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCGTVLGGPKLPERVGFSEDIN 62 Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP SFDAREQW CPTI +IRDQGSCGS WAFGAVEA+SDRICIHTN V+VEVSAEDLL Sbjct: 63 LPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 122 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 TCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCEHHVNG+RPPCT Sbjct: 123 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCT 182 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 GEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF+V+SDF Sbjct: 183 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 242 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 L YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKILRG++HC Sbjct: 243 LTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRGENHC 302 Query: 320 GIESEVVAGIPRTDQYWEKI 339 GIESE+VAGIPRT QYW + Sbjct: 303 GIESEIVAGIPRTQQYWGRF 322 >3CBK-A nrPDB Length = 266 Score = 369 bits (948), Expect = e-103, Method: Composition-based stats. Identities = 263/266 (98%), Positives = 264/266 (99%) Query: 74 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEV 133 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGS WAFGAVEAISDRICIHTNAHVSVEV Sbjct: 1 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEV 60 Query: 134 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNG 193 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE HVNG Sbjct: 61 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNG 120 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 180 Query: 254 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL Sbjct: 181 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 240 Query: 314 RGQDHCGIESEVVAGIPRTDQYWEKI 339 RGQDHCGIESEVVAGIPRTDQYWEKI Sbjct: 241 RGQDHCGIESEVVAGIPRTDQYWEKI 266 >1CPJ-A nrPDB Length = 260 Score = 349 bits (894), Expect = 1e-96, Method: Composition-based stats. Identities = 214/260 (82%), Positives = 239/260 (91%) Query: 74 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEV 133 F+ED+ LP SFDAREQW CPTI +IRDQGSCGSCWAFGAVEA+SDRICIHTN V+VEV Sbjct: 1 FSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEV 60 Query: 134 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNG 193 SAEDLLTCCG CGDGCNGGYP+ AWNFWTRKGLVSGG+Y SH+GC PY+IPPCEHHVNG Sbjct: 61 SAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNG 120 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 +RPPCTGEGDTPKC+K+CE GYS +YK+DKHYGY SYSVS+SEK+IMAEIYKNGPVEGAF Sbjct: 121 ARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAF 180 Query: 254 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 +V+SDFL YKSGVY+H G++MGGHAIRILGWG+ENG PYWLVANSWN DWGDNGFFKIL Sbjct: 181 TVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKIL 240 Query: 314 RGQDHCGIESEVVAGIPRTD 333 RG++HCGIESE+VAGIPRT Sbjct: 241 RGENHCGIESEIVAGIPRTQ 260 >4I04-A nrPDB Length = 323 Score = 343 bits (879), Expect = 7e-95, Method: Composition-based stats. Identities = 161/313 (51%), Positives = 216/313 (69%), Gaps = 8/313 (2%) Query: 23 FHPLSDELVNYVNKR-NTTWQA--GHNFYNVDMSYLK---RLCGTFLGGPKPPQRVMFTE 76 F PLSD++++Y+N+ N W+A + F+++D + ++ R L + P Sbjct: 9 FEPLSDDIISYINEHPNAGWRAEKSNRFHSLDDARIQMGARREEPDLRRTRRPTVDHNDW 68 Query: 77 DLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAE 136 ++++P+SFD+R++WP+C +I IRDQ CGS WAFGAVEA+SDR CI + +VE+SA Sbjct: 69 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAV 128 Query: 137 DLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRP 196 DLL+CC S CG GC GG AW++W ++G+V+G E+H GC PY P CEHH G P Sbjct: 129 DLLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYP 187 Query: 197 PCTGE-GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255 PC + TP+C + C+ Y Y QDKH G +SY+V N EK I EI K GPVE F+V Sbjct: 188 PCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV 247 Query: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 Y DFL YKSG+Y+H+TGE +GGHAIRI+GWGVEN PYWL+ANSWN DWG+NG+F+I+RG Sbjct: 248 YEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRG 307 Query: 316 QDHCGIESEVVAG 328 +D C IESEV AG Sbjct: 308 RDECSIESEVTAG 320 >2DCB-A nrPDB Length = 256 Score = 323 bits (827), Expect = 8e-89, Method: Composition-based stats. Identities = 226/256 (88%), Positives = 243/256 (94%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP SFDAREQWP CPTIKEIRDQGSCGSCWAFGAVEAISDRICIH+N V+VEVSAED+L Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 TCCG CGDGCNGG+P+ AWNFWT+KGLVSGGLY SHVGCRPYSIPPCEHHVNGSRPPCT Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 GEGDTPKCSK CEPGYSP+YK+DKH+G +SYSV+N+EK+IMAEIYKNGPVEGAFSVYSDF Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDF 180 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 LLYKSGVYQHV+GE+MGGHAIRILGWGVENGTPYWLV NSWNTDWGDNGFFKILRGQDHC Sbjct: 181 LLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHC 240 Query: 320 GIESEVVAGIPRTDQY 335 GIESE+VAG+P T QY Sbjct: 241 GIESEIVAGMPCTHQY 256 >4I05-A nrPDB Length = 285 Score = 318 bits (815), Expect = 2e-87, Method: Composition-based stats. Identities = 150/273 (54%), Positives = 191/273 (69%), Gaps = 2/273 (0%) Query: 57 RLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEA 116 R L + P ++++P+SFD+R++WP+C +I IRDQ CGSCWAFGAVEA Sbjct: 11 RREEPDLRRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEA 70 Query: 117 ISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESH 176 +SDR CI + +VE+SA DLL+CC S CG GC GG AW++W ++G+V+G E+H Sbjct: 71 MSDRSCIQSGGKQNVELSAVDLLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENH 129 Query: 177 VGCRPYSIPPCEHHVNGSRPPCTGE-GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNS 235 GC PY P CEHH G PPC + TP+C + C+ Y Y QDKH G +SY+V N Sbjct: 130 AGCEPYPFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKND 189 Query: 236 EKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWL 295 EK I EI K GPVE F+VY DFL YKSG+Y+H+TGE +GGHAIRI+GWGVEN PYWL Sbjct: 190 EKAIQKEIMKYGPVEAGFTVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWL 249 Query: 296 VANSWNTDWGDNGFFKILRGQDHCGIESEVVAG 328 +ANSWN DWG+NG+F+I+RG+D C IESEV AG Sbjct: 250 IANSWNEDWGENGYFRIVRGRDECSIESEVTAG 282 >5OGQ-A nrPDB Length = 254 Score = 301 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 147/252 (58%), Positives = 186/252 (73%), Gaps = 2/252 (0%) Query: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 +++P+SFD+R++WP+C +I IRDQ CGSCWAFGAVEA+SDR CI + +VE+SA D Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 LL+CC S CG GC GG AW++W ++G+V+G E+H GC PY P CEHH G PP Sbjct: 61 LLSCCES-CGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPP 119 Query: 198 CTGE-GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY 256 C + TP+C + C+ Y Y QDKH G +SY+V N EK I EI K GPVE F+VY Sbjct: 120 CGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVY 179 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 DFL YKSG+Y+H+TGE +GGHAIRI+GWGVEN PYWL+ANSWN DWG+NG+F+I+RG+ Sbjct: 180 EDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGR 239 Query: 317 DHCGIESEVVAG 328 D C IESEV AG Sbjct: 240 DECSIESEVTAG 251 >4HWY-A nrPDB Length = 340 Score = 292 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 141/317 (44%), Positives = 181/317 (57%), Gaps = 24/317 (7%) Query: 25 PLSDELVNYVNKRNTT-WQAGHN--FYNVDMSYLKRLCGTFLGGPKP---PQRVMFTEDL 78 LS V+ VN+ N W+A ++ N+ + KRL G P+R E+ Sbjct: 31 VLSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKKNNNASILPKRRFTEEEA 90 Query: 79 K--LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAE 136 + LP+SFD+ E WP CPTI +I DQ +CGSCWA A A+SDR C V +SA Sbjct: 91 RAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTM-GGVQDVHISAG 149 Query: 137 DLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGS-- 194 DLL CC CGDGCNGG P AW +++ GLVS C+PY P C HH Sbjct: 150 DLLACCSD-CGDGCNGGDPDRAWAYFSSTGLVSDY-------CQPYPFPHCSHHSKSKNG 201 Query: 195 RPPCTGEG-DTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 PPC+ DTPKC+ C+ PT + + SY++ E D M E++ GP E AF Sbjct: 202 YPPCSQFNFDTPKCNYTCDD---PTIPVVNYRSWTSYAL-QGEDDYMRELFFRGPFEVAF 257 Query: 254 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 VY DF+ Y SGVY HV+G+ +GGHA+R++GWG NG PYW +ANSWNT+WG +G+F I Sbjct: 258 DVYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIR 317 Query: 314 RGQDHCGIESEVVAGIP 330 RG CGIE AGIP Sbjct: 318 RGSSECGIEDGGSAGIP 334 >1CSB-B nrPDB Length = 205 Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 205/205 (100%), Positives = 205/205 (100%) Query: 129 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 188 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE Sbjct: 1 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 60 Query: 189 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 248 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP Sbjct: 61 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 120 Query: 249 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG 308 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG Sbjct: 121 VEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNG 180 Query: 309 FFKILRGQDHCGIESEVVAGIPRTD 333 FFKILRGQDHCGIESEVVAGIPRTD Sbjct: 181 FFKILRGQDHCGIESEVVAGIPRTD 205 >5FPW-A nrPDB Length = 321 Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 127/318 (39%), Positives = 174/318 (54%), Gaps = 20/318 (6%) Query: 25 PLSDELVNYVNKRNT-TWQAGHN--FYNVDMSYLKRLCGTFLGGPKPPQRVMFTED---L 78 L+ V+ +N+ N W+A +N N+ + KRL G ++ V FTE+ Sbjct: 14 VLTKTFVDRINQLNGGMWKAVYNGKMQNITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRT 73 Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 +LP SFD+ E+WP CPTI+EI DQ +C + WA ISDR C + +SA L Sbjct: 74 ELPESFDSAEKWPNCPTIREIADQSACRASWAVSTASVISDRYCTV-GGVQQLRISAAHL 132 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHH-VNGSRPP 197 L+CC G GG+P AW ++ G+ S C+PY P CEH G++ P Sbjct: 133 LSCCKQCGGGC-KGGFPGFAWRYYVEYGIASSY-------CQPYPFPHCEHRGAQGNKTP 184 Query: 198 CTGEG-DTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY 256 C+ DTPKC C P K + G +Y + + E+D E+Y NGP F VY Sbjct: 185 CSKYNFDTPKCQATCTDKSIPLVK---YRGSATYLLLHGEEDYKRELYFNGPFVAVFYVY 241 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 +D YKSGVY+HV G+ +GG A++++GWG NGTPYW VAN+W+TDWG +G+ ILRG Sbjct: 242 TDLFAYKSGVYRHVDGDFLGGTAVKVVGWGKLNGTPYWKVANTWDTDWGMDGYLLILRGN 301 Query: 317 DHCGIESEVVAGIPRTDQ 334 + C IE AG P T Q Sbjct: 302 NECNIEHLGFAGTPETSQ 319 >1JQP-A nrPDB Length = 438 Score = 273 bits (697), Expect = 9e-74, Method: Composition-based stats. Identities = 88/317 (27%), Positives = 143/317 (45%), Gaps = 46/317 (14%) Query: 29 ELVNYVNKRNTTWQAG--HNFYNVDMSYLKRLCG----TFLGGPKPPQRVMFTEDLKLPA 82 V +N +W A + + + L R G P P + + L LP Sbjct: 149 NFVKAINSVQKSWTATTYRRYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPE 208 Query: 83 SFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCC 142 S+D R + +R+Q SCGSC++F ++ + RI I TN + +S +++++C Sbjct: 209 SWDWRNV-RGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC- 266 Query: 143 GSMCGDGCNGGYPA-EAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGE 201 S GC+GG+P A + G+V C PY+ + PC + Sbjct: 267 -SPYAQGCDGGFPYLIAGKYAQDFGVVEE-------NCFPYTA---------TDAPCKPK 309 Query: 202 GDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLL 261 + + Y ++Y + +E + E+ K+GP+ AF V+ DFL Sbjct: 310 ENCLR------------YYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLH 357 Query: 262 YKSGVYQHV------TGEMMGGHAIRILGWGVE--NGTPYWLVANSWNTDWGDNGFFKIL 313 Y SG+Y H + HA+ ++G+G + G YW+V NSW + WG++G+F+I Sbjct: 358 YHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIR 417 Query: 314 RGQDHCGIESEVVAGIP 330 RG D C IES +A IP Sbjct: 418 RGTDECAIESIAMAAIP 434 >3PDF-A nrPDB Length = 441 Score = 270 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 98/335 (29%), Positives = 148/335 (44%), Gaps = 49/335 (14%) Query: 14 LANARSRPSFHPLS--DELVNYVNKRNTTWQAG--HNFYNVDMSYLKRLCG-----TFLG 64 L N++ + S V +N +W A + + + + R G Sbjct: 132 LKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRP 191 Query: 65 GPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124 P P + + L LP S+D R + +R+Q SCGSC++F ++ + RI I Sbjct: 192 KPAPLTAEIQQKILFLPTSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRIL 250 Query: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPA-EAWNFWTRKGLVSGGLYESHVGCRPYS 183 TN + +S +++++C S GC GG+P A + GLV C PY+ Sbjct: 251 TNNSQTPILSPQEVVSC--SQYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT 301 Query: 184 IPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEI 243 G+ PC + D + Y + HY Y N E + E+ Sbjct: 302 ---------GTDSPCKMKEDCFR-----------YYSSEYHYVGGFYGGCN-EALMKLEL 340 Query: 244 YKNGPVEGAFSVYSDFLLYKSGVYQHV------TGEMMGGHAIRILGWGVEN--GTPYWL 295 +GP+ AF VY DFL YK G+Y H + HA+ ++G+G ++ G YW+ Sbjct: 341 VHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWI 400 Query: 296 VANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 V NSW T WG+NG+F+I RG D C IES VA P Sbjct: 401 VKNSWGTGWGENGYFRIRRGTDECAIESIAVAATP 435 >4QRX-A nrPDB Length = 363 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 83/321 (25%), Positives = 124/321 (38%), Gaps = 58/321 (18%) Query: 23 FHPLSDEL--VNYVNKRNTTWQAGHNFYNVDMS-------YLKRLCGTFLGGPKPPQRVM 73 F D L ++ NK+N ++ G N + DMS Y + G + + V+ Sbjct: 87 FEIFKDNLKYIDETNKKNNSYWLGLNVF-ADMSNDEFKEKYTGSIAGNYTTTELSYEEVL 145 Query: 74 FTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEV 133 D+ +P D W Q + +++QGSCGS WAF AV I I I T E Sbjct: 146 NDGDVNIPEYVD----WRQKGAVTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNL--NEY 199 Query: 134 SAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNG 193 S ++LL C GCNGGYP A + G+ Y PY G Sbjct: 200 SEQELLDC--DRRSYGCNGGYPWSALQLVAQYGIHYRNTY-------PY---------EG 241 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 + C P +K Y +E ++ I Sbjct: 242 VQRYCRSREKGPYAAKTDGVRQVQPY---------------NEGALLYSIANQPVSVVLE 286 Query: 254 SVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 + DF LY+ G++ G + HA+ +G+G Y L+ NSW T WG+NG+ +I Sbjct: 287 AAGKDFQLYRGGIFVGPCGNKV-DHAVAAVGYG----PNYILIRNSWGTGWGENGYIRIK 341 Query: 314 RGQDH----CGIESEVVAGIP 330 RG + CG+ + + Sbjct: 342 RGTGNSYGVCGLYTSSFYPVK 362 >1PCI-A nrPDB Length = 322 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 78/320 (24%), Positives = 124/320 (38%), Gaps = 51/320 (15%) Query: 23 FHPLSDEL--VNYVNKRNTTWQAGHNFYN--VDMSYLKRLCGTFLGGP--KPPQRVMFTE 76 F D L ++ NK+N ++ G N + + + ++ G+ + + E Sbjct: 43 FEIFKDNLNYIDETNKKNNSYWLGLNEFADLSNDEFNEKYVGSLIDATIEQSYDEEFINE 102 Query: 77 D-LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSA 135 D + LP + D W + + +R QGSCGSCWAF AV + I T V E+S Sbjct: 103 DIVNLPENVD----WRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLV--ELSE 156 Query: 136 EDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSR 195 ++L+ C GC GGYP A + + G+ Y PY Sbjct: 157 QELVDC--ERRSHGCKGGYPPYALEYVAKNGIHLRSKY-------PYKAKQGTCRAKQVG 207 Query: 196 PPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255 P + N+E +++ I K S Sbjct: 208 GPIVKTSGVGRVQ------------------------PNNEGNLLNAIAKQPVSVVVESK 243 Query: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 F LYK G+++ G + G A+ +G+G G Y L+ NSW T WG+ G+ +I R Sbjct: 244 GRPFQLYKGGIFEGPCGTKVDG-AVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRA 302 Query: 316 QDHCGIESEVVAGIPRTDQY 335 + S V G+ ++ Y Sbjct: 303 PGN----SPGVCGLYKSSYY 318 >5EF4-A nrPDB Length = 385 Score = 248 bits (632), Expect = 4e-66, Method: Composition-based stats. Identities = 73/334 (21%), Positives = 123/334 (36%), Gaps = 63/334 (18%) Query: 18 RSRPSFHPLSDEL--VNYVNKRNTTWQ-------------AGHNFYNVDMSYLKRLCGTF 62 RS F+ + ++ NK + ++ + + N +S+ + L G+ Sbjct: 51 RSPERFNVFKYNVRRIHESNKMDKPYKLKVNEFADMTNLEFVNTYANSKISHFQALRGSA 110 Query: 63 LGG--PKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR 120 G P + ++ K+P D RE+ + +++ QG CGSCWAF AV A+ Sbjct: 111 PGSIDTDPNKDFIYANVTKIPDKVDWREK----NAVTDVKGQGGCGSCWAFAAVVALEGI 166 Query: 121 ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR 180 I T V + S + L+ C M GC+GG A+ + + G + Sbjct: 167 NAIRTGKLV--KFSEQQLVDC--DMTNAGCDGGLMEPAFTYVIKHGGI------------ 210 Query: 181 PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM 240 P + G R C +D +V +++ + Sbjct: 211 ---APEASYPYVGKRETCDKAKI-----------------KDVLKIDGRQNVPGLDEEAL 250 Query: 241 AEIYKNGPVEGAFSVYSD-FLLYKSGVYQHVTGEMMGGHAIRILGWG-VENGTPYWLVAN 298 + + PV + Y GVY G H + I+G+G E G +W V N Sbjct: 251 RKAVAHQPVATGIQLSGHGLQFYSEGVYTGDCGTEP-NHGVGIVGYGENEKGIKFWTVKN 309 Query: 299 SWNTDWGDNGFFKILRG---QDHCGIESEVVAGI 329 SW WG+ G+ + RG + CG+ I Sbjct: 310 SWGPTWGEKGYIHLQRGARKEGLCGVAMHSSFPI 343 >1CJL-A nrPDB Length = 312 Score = 245 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 76/299 (25%), Positives = 119/299 (39%), Gaps = 47/299 (15%) Query: 40 TWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDL--KLPASFDAREQWPQCPTIK 97 ++ N + S R L KP + +F E L + P S D RE+ + Sbjct: 51 SFTMAMNAFGDMTSEEFRQVMNGLQNRKPRKGKVFQEPLFYEAPRSVDWREK----GYVT 106 Query: 98 EIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAE 157 +++QG CGS WAF A A+ ++ T +S+ S ++L+ C G +GCNGG Sbjct: 107 PVKNQGQCGSSWAFSATGALEGQMFRKTGRLISL--SEQNLVDCSGPEGNEGCNGGLMDY 164 Query: 158 AWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSP 217 A+ + G + PY Y+P Sbjct: 165 AFQYVQDNGGLDS------EESYPYEATEESC------------------------KYNP 194 Query: 218 TYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSDFLLYKSGVY-QHVTGEMM 275 Y G+ + EK +M + GP+ A + FL YK G+Y + Sbjct: 195 KYSVANDAGF--VDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSED 252 Query: 276 GGHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFKILRG-QDHCGIESEVVAGI 329 H + ++G+G E +G YWLV NSW +WG G+ K+ + ++HCGI S Sbjct: 253 MDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 311 >3HWN-A nrPDB Length = 258 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 72/275 (26%), Positives = 112/275 (40%), Gaps = 47/275 (17%) Query: 64 GGPKPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRI 121 KP + +F E L + P S D RE+ + +++QG CGSCWAF A A+ ++ Sbjct: 21 QNRKPRKGKVFQEPLFYEAPRSVDWREK----GYVTPVKNQGQCGSCWAFSATGALEGQM 76 Query: 122 CIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRP 181 T +S+ S ++L+ C G +GCNGG A+ + G + P Sbjct: 77 FRKTGRLISL--SEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS------EESYP 128 Query: 182 YSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMA 241 Y Y+P Y G+ + EK +M Sbjct: 129 YEATEESC------------------------KYNPKYSVANDAGF--VDIPKQEKALMK 162 Query: 242 EIYKNGPVEGAFSV-YSDFLLYKSGVY-QHVTGEMMGGHAIRILGWGVE----NGTPYWL 295 + GP+ A + FL YK G+Y + H + ++G+G E + YWL Sbjct: 163 AVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWL 222 Query: 296 VANSWNTDWGDNGFFKILRG-QDHCGIESEVVAGI 329 V NSW +WG G+ K+ + ++HCGI S Sbjct: 223 VKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 257 >1S4V-A nrPDB Length = 229 Score = 243 bits (620), Expect = 8e-65, Method: Composition-based stats. Identities = 71/260 (27%), Positives = 110/260 (42%), Gaps = 45/260 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +PAS D W + + ++DQG CGSCWAF + A+ I TN VS+ S ++L+ Sbjct: 2 VPASVD----WRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSL--SEQELV 55 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GCNGG A+ F ++G ++ PY V Sbjct: 56 DC-DTDQNQGCNGGLMDYAFEFIKQRGGIT------TEANYPYEAYDGTCDV-------- 100 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS-D 258 +P D H +V ++++ + + N PV A D Sbjct: 101 ------------SKENAPAVSIDGHE-----NVPENDENALLKAVANQPVSVAIDAGGSD 143 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVE-NGTPYWLVANSWNTDWGDNGFFKILRG-- 315 F Y GV+ G + H + I+G+G +GT YW V NSW +WG+ G+ ++ RG Sbjct: 144 FQFYSEGVFTGSCGTEL-DHGVAIVGYGTTIDGTKYWTVKNSWGPEWGEKGYIRMERGIS 202 Query: 316 --QDHCGIESEVVAGIPRTD 333 + CGI E I ++ Sbjct: 203 DKEGLCGIAMEASYPIKKSS 222 >6CZS-A nrPDB Length = 335 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 78/307 (25%), Positives = 133/307 (43%), Gaps = 45/307 (14%) Query: 31 VNYVNKRNTTWQAGHNFYNVDMSYLK---RLCGTFLGGPKPPQRVMFTEDLKLPASFDAR 87 +N N N T++ N ++ DMS+ + + + + P S D R Sbjct: 65 INAHNNGNHTFKMALNQFS-DMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWR 123 Query: 88 EQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCG 147 ++ + +++QG+CGS W F A+ I I T +S+ + + L+ C Sbjct: 124 KKG---NFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNN 178 Query: 148 DGCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPK 206 GC GG P++A+ + KG++ Y PY +G Sbjct: 179 HGCQGGLPSQAFEYILYNKGIMGEDTY-------PY------------------QGKDGY 213 Query: 207 CSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV 266 C +PG + + +D + E+ ++ + PV AF V DF++Y++G+ Sbjct: 214 CK--FQPGKAIGFVKD-----VANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGI 266 Query: 267 YQHVTGEMMG---GHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIES 323 Y + HA+ +G+G +NG PYW+V NSW WG NG+F I RG++ CG+ + Sbjct: 267 YSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAA 326 Query: 324 EVVAGIP 330 IP Sbjct: 327 CASYPIP 333 >1SP4-B nrPDB Length = 205 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 179/205 (87%), Positives = 196/205 (95%) Query: 128 HVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPC 187 V+VEVSAED+LTCCG CGDGCNGG+P+ AWNFWT+KGLVSGGLY SHVGCRPYSIPPC Sbjct: 1 RVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPC 60 Query: 188 EHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNG 247 EHHVNGSRPPCTGEGDTPKC+K CEPGYSP+YK+DKH+G +SYSV+N+EK+IMAEIYKNG Sbjct: 61 EHHVNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNG 120 Query: 248 PVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDN 307 PVEGAFSVYSDFLLYKSGVYQHV+GE+MGGHAIRILGWGVENGTPYWLV NSWNTDWGDN Sbjct: 121 PVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDN 180 Query: 308 GFFKILRGQDHCGIESEVVAGIPRT 332 GFFKILRGQDHCGIESE+VAG+P T Sbjct: 181 GFFKILRGQDHCGIESEIVAGMPCT 205 >3QJ3-A nrPDB Length = 331 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 79/266 (29%), Positives = 115/266 (43%), Gaps = 41/266 (15%) Query: 67 KPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTN 126 K + + ++ PASFD R+Q + +++QGSCGS WAF + AI ++ I Sbjct: 103 KTREDLGLNASVRYPASFDWRDQ----GMVSPVKNQGSCGSSWAFSSTGAIESQMKIANG 158 Query: 127 AHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPP 186 A VS + L+ C + GC+GG+ +A+ + + G + G PY + Sbjct: 159 AGYDSSVSEQQLVDCVPN--ALGCSGGWMNDAFTYVAQNGGIDS------EGAYPYEMAD 210 Query: 187 CEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN 246 H + ++ G Y E + + Sbjct: 211 GNCHYDPNQVAARLSGYV-------------------------YLSGPDENMLADMVATK 245 Query: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVENGTPYWLVANSWNTDWG 305 GPV AF F Y GVY + T E HA+ I+G+G ENG YWLV NSW WG Sbjct: 246 GPVAVAFDADDPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWG 305 Query: 306 DNGFFKILRG-QDHCGIESEVVAGIP 330 +G+FKI R +HCGI VA +P Sbjct: 306 LDGYFKIARNANNHCGIA--GVASVP 329 >1NB3-A nrPDB Length = 220 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 73/254 (28%), Positives = 113/254 (44%), Gaps = 41/254 (16%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D R++ + +++QGSCGSCW F A+ + I T +S+ + + L+ Sbjct: 2 PPSMDWRKKG---NFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSL--AEQQLVD 56 Query: 141 CCGSMCGDGCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GC GG P++A+ + KG++ Y PY G C Sbjct: 57 CAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTY-------PY---------KGQDDHCK 100 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 + D K + N E+ ++ + PV AF V +DF Sbjct: 101 FQPD----------------KAIAFVKDVANITMNDEEAMVEAVALYNPVSFAFEVTNDF 144 Query: 260 LLYKSGVYQHVTGEMMG---GHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 L+Y+ G+Y + HA+ +G+G ENG PYW+V NSW WG NG+F I RG+ Sbjct: 145 LMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLIERGK 204 Query: 317 DHCGIESEVVAGIP 330 + CG+ + IP Sbjct: 205 NMCGLAACASYPIP 218 >4YYR-A nrPDB Length = 222 Score = 237 bits (604), Expect = 6e-63, Method: Composition-based stats. Identities = 73/259 (28%), Positives = 108/259 (41%), Gaps = 43/259 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D R Q + IR+QG CGSCWAF V + I T+ S+ S + L+ Sbjct: 1 LPETVDWRIQ----GAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSL--SEQQLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C S GC+GG+ +A+++ + G ++ PY+ E Sbjct: 55 DCATSYKNLGCSGGWMTKAYDYIIKNGGITS------QSNYPYTAKKGE----------- 97 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD- 258 C+K T +H N+E + + N PV Sbjct: 98 -------CNKDLASQIVATIDSYEH------VPRNNENALKNAVA-NQPVSVTIEAGGRA 143 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG--- 315 F LYKSGV+ G + HA+ +G+G EN YWLV NSW T+WG+ G+ K+ R Sbjct: 144 FELYKSGVFVGSCGTKL-DHAVVAIGYGSENDVDYWLVRNSWGTNWGERGYIKLQRNVAE 202 Query: 316 -QDHCGIESEVVAGIPRTD 333 CGI + + +T Sbjct: 203 PTGKCGIAMQSTYPVKKTS 221 >3P5W-A nrPDB Length = 220 Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats. Identities = 65/256 (25%), Positives = 109/256 (42%), Gaps = 44/256 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D W + +I+DQG CGSCWAF + A+ I T +S+ S ++L+ Sbjct: 1 LPDYVD----WRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISL--SEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GC+GG+ + + F G + + PY+ + +++ Sbjct: 55 DCGRTQNTRGCDGGFMTDGFQFIINNGGI------NTEANYPYTAEEGQCNLD------- 101 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSY-SVSNSEKDIMAEIYKNGPVEGAFSVYS- 257 +Q+K+ ++Y +V + + + PV A Sbjct: 102 -------------------LQQEKYVSIDTYENVPYNNEWALQTAVAYQPVSVALEAAGY 142 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--- 314 +F Y SG++ G + HA+ I+G+G E G YW+V NSW T WG+ G+ +I R Sbjct: 143 NFQHYSSGIFTGPCGTAV-DHAVTIVGYGTEGGIDYWIVKNSWGTTWGEEGYMRIQRNVG 201 Query: 315 GQDHCGIESEVVAGIP 330 G CGI + + Sbjct: 202 GVGQCGIAKKASYPVK 217 >2C0Y-A nrPDB Length = 315 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 110/253 (43%), Gaps = 42/253 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D RE+ + E++ QGSCG+ WAF AV A+ ++ + T VS+ SA++L+ Sbjct: 99 LPDSVDWREK----GCVTEVKYQGSCGAAWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 152 Query: 140 TCCGS-MCGDGCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 C GCNGG+ A+ + KG+ S Y PY + + Sbjct: 153 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 205 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 T CSK E Y E + + GPV + Sbjct: 206 AT-------CSKYTELPY------------------GREDVLKEAVANKGPVSVGVDARH 240 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R + Sbjct: 241 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 300 Query: 317 -DHCGIESEVVAG 328 +HCGI S Sbjct: 301 GNHCGIASFPSYP 313 >4BS5-A nrPDB Length = 225 Score = 235 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 71/253 (28%), Positives = 109/253 (43%), Gaps = 41/253 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D RE+ + E++ QGSCG+CWAF AV A+ ++ + T +S+ SA++L+ Sbjct: 8 LPDTVDWREK----GCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISL--SAQNLV 61 Query: 140 TCCGS--MCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 C GC GGY EA+ + G + PY + H N Sbjct: 62 DCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEAD------ASYPYKAMDEKCHYNSKNRA 115 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 T CS+ + + E + + GPV + Sbjct: 116 AT-------CSRYIQLPF------------------GDEDALKEAVATKGPVSVGIDASH 150 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR-G 315 S F YKSGVY + H + ++G+G +G YWLV NSW ++GD G+ ++ R Sbjct: 151 SSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNN 210 Query: 316 QDHCGIESEVVAG 328 ++HCGI S Sbjct: 211 KNHCGIASYCSYP 223 >3OF9-A nrPDB Length = 221 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 67/258 (25%), Positives = 105/258 (40%), Gaps = 45/258 (17%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 + P S D RE+ + +++QG CGSCWAF A A+ ++ T +S+ S ++L Sbjct: 1 EAPRSVDWREK----GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISL--SEQNL 54 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 + C G +GCNGG A+ + G + PY Sbjct: 55 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS------EESYPYEATEESC--------- 99 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YS 257 Y+P Y G+ + EK +M + GP+ A + Sbjct: 100 ---------------KYNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAGHE 142 Query: 258 DFLLYKSGVY-QHVTGEMMGGHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFKI 312 FL YK G+Y + H + ++G+G E + YWLV NSW +WG G+ K+ Sbjct: 143 SFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 202 Query: 313 LRG-QDHCGIESEVVAGI 329 + ++HCGI S Sbjct: 203 AKDRRNHCGIASAASYPT 220 >4P6E-A nrPDB Length = 230 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 110/253 (43%), Gaps = 42/253 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D RE+ + E++ QGSCG+CWAF AV A+ ++ + T VS+ SA++L+ Sbjct: 7 LPDSVDWREK----GCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSL--SAQNLV 60 Query: 140 TCCGS-MCGDGCNGGYPAEAWNFWTRK-GLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 C GCNGG+ A+ + G+ S Y PY + + Sbjct: 61 DCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASY-------PYKAMDQKCQYDSKYRA 113 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 T CSK E Y E + + GPV + Sbjct: 114 AT-------CSKYTELPY------------------GREDVLKEAVANKGPVSVGVDARH 148 Query: 257 SDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 F LY+SGVY + H + ++G+G NG YWLV NSW ++G+ G+ ++ R + Sbjct: 149 PSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNK 208 Query: 317 -DHCGIESEVVAG 328 +HCGI S Sbjct: 209 GNHCGIASFPSYP 221 >3KFQ-A nrPDB Length = 221 Score = 231 bits (588), Expect = 4e-61, Method: Composition-based stats. Identities = 67/256 (26%), Positives = 104/256 (40%), Gaps = 44/256 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D W + + +++Q CGSCWAF A A+ ++ T VS+ S ++L+ Sbjct: 1 LPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQNLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GCNGG+ A A+ + G + PY Sbjct: 55 DCSRPQGNQGCNGGFMARAFQYVKENGGLDS------EESYPYVAVDEIC---------- 98 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSD 258 Y P + G+ + EK +M + GP+ A +S Sbjct: 99 --------------KYRPENSVAQDTGF-TVVAPGKEKALMKAVATVGPISVAMDAGHSS 143 Query: 259 FLLYKSGVY-QHVTGEMMGGHAIRILGWG----VENGTPYWLVANSWNTDWGDNGFFKIL 313 F YKSG+Y + H + ++G+G + + YWLV NSW +WG NG+ KI Sbjct: 144 FQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDNSKYWLVKNSWGPEWGSNGYVKIA 203 Query: 314 RGQ-DHCGIESEVVAG 328 + + +HCGI + Sbjct: 204 KDKNNHCGIATAASYP 219 >2FO5-A nrPDB Length = 262 Score = 230 bits (587), Expect = 5e-61, Method: Composition-based stats. Identities = 69/263 (26%), Positives = 106/263 (40%), Gaps = 44/263 (16%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 LP S D W Q + ++DQG CGSCWAF V ++ I T + VS+ S ++L Sbjct: 3 DLPPSVD----WRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSL--SEQEL 56 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRK-GLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 + C + DGC GG A+ + GL++ Y PY +V Sbjct: 57 IDC-DTADNDGCQGGLMDNAFEYIKNNGGLITEAAY-------PYRAARGTCNV------ 102 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS 257 + H + +NSE+D+ + N PV A Sbjct: 103 ---------------ARAAQNSPVVVHIDGHQDVPANSEEDLARAVA-NQPVSVAVEASG 146 Query: 258 -DFLLYKSGVYQHVTGEMMGGHAIRILGWGV-ENGTPYWLVANSWNTDWGDNGFFKILRG 315 F+ Y GV+ G + H + ++G+GV E+G YW V NSW WG+ G+ ++ + Sbjct: 147 KAFMFYSEGVFTGECGTEL-DHGVAVVGYGVAEDGKAYWTVKNSWGPSWGEQGYIRVEKD 205 Query: 316 QDH----CGIESEVVAGIPRTDQ 334 CGI E + + Sbjct: 206 SGASGGLCGIAMEASYPVKTYSK 228 >2O6X-A nrPDB Length = 310 Score = 230 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 75/308 (24%), Positives = 122/308 (39%), Gaps = 46/308 (14%) Query: 30 LVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQ 89 LV Y N + L P + + +P D RE Sbjct: 46 LVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEA----NNRAVPDKIDWRE- 100 Query: 90 WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 149 + E++DQG+CGS WAF + + N S+ S + L+ C +G Sbjct: 101 ---SGYVTEVKDQGNCGSGWAFSTTGTMEGQY--MKNERTSISFSEQQLVDCSRPWGNNG 155 Query: 150 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209 C GG A+ + + GL + Y PY+ + Sbjct: 156 CGGGLMENAYQYLKQFGLETESSY-------PYTAVEGQCR------------------- 189 Query: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQH 269 Y+ K G+ + S SE ++ + GP A V SDF++Y+SG+YQ Sbjct: 190 -----YNKQLGVAKVTGFYTVH-SGSEVELKNLVGAEGPAAVAVDVESDFMMYRSGIYQS 243 Query: 270 -VTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ-DHCGIESEVVA 327 + HA+ +G+G + GT YW+V NSW WG+ G+ +++R + + CGI S +A Sbjct: 244 QTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCGIAS--LA 301 Query: 328 GIPRTDQY 335 +P ++ Sbjct: 302 SLPMVARF 309 >7PCK-A nrPDB Length = 314 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 72/314 (22%), Positives = 127/314 (40%), Gaps = 56/314 (17%) Query: 31 VNYVNKRNTTWQAGHNFYNVDMSYL---------KRLCGTFLGGPKPPQRV---MFTEDL 78 + Y++ N G + Y + M++L +++ G + + + Sbjct: 39 LKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEG 98 Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 + P S D R++ + +++QG CGSCWAF +V A+ ++ T + +S ++L Sbjct: 99 RAPDSVDYRKK----GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKL--LNLSPQNL 152 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRK-GLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 + C DGC GGY A+ + + G+ S Y Sbjct: 153 VDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAY------------------------ 186 Query: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY- 256 P + Y+PT K K GY N EK + + + GPV A Sbjct: 187 -------PYVGQEESCMYNPTGKAAKCRGYREIPEGN-EKALKRAVARVGPVSVAIDASL 238 Query: 257 SDFLLYKSGV-YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG 315 + F Y GV Y HA+ +G+G++ G +W++ NSW +WG+ G+ + R Sbjct: 239 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 298 Query: 316 QDH-CGIESEVVAG 328 +++ CGI + Sbjct: 299 KNNACGIANLASFP 312 >1AEC-A nrPDB Length = 218 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 107/256 (41%), Gaps = 44/256 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ D W + +I+ QG CG CWAF A+ + I T +S+ S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISL--SEQELI 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GCNGGY + + F G + + PY+ E +V+ Sbjct: 55 DCGRTQNTRGCNGGYITDGFQFIINNGGI------NTEENYPYTAQDGECNVDLQNE--- 105 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSY-SVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 K+ ++Y +V + + + PV A D Sbjct: 106 -----------------------KYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGD 142 Query: 259 -FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--- 314 F Y SG++ G + HA+ I+G+G E G YW+V NSW+T WG+ G+ +ILR Sbjct: 143 AFKQYSSGIFTGPCGTAI-DHAVTIVGYGTEGGIDYWIVKNSWDTTWGEEGYMRILRNVG 201 Query: 315 GQDHCGIESEVVAGIP 330 G CGI + + Sbjct: 202 GAGTCGIATMPSYPVK 217 >3QT4-A nrPDB Length = 329 Score = 227 bits (579), Expect = 5e-60, Method: Composition-based stats. Identities = 72/320 (22%), Positives = 126/320 (39%), Gaps = 58/320 (18%) Query: 25 PLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFL---------GGPKPPQ--RVM 73 D V + + N ++ G Y+ M+ + PK P+ R+ Sbjct: 50 IFKDN-VAKIAEHNAKFEKGEVTYSKAMNQFGDMSKEEFLAYVNRGKAQKPKHPENLRMP 108 Query: 74 FTEDLK-LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVE 132 + K L AS D R + E++DQG CGS W+F A+ ++ + S+ Sbjct: 109 YVSSKKPLAASVDWRS-----NAVSEVKDQGQCGSSWSFSTTGAVEGQLALQRGRLTSL- 162 Query: 133 VSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIP--PCEHH 190 S ++L+ C S GC+GG+ A+++ G++S Y PY C Sbjct: 163 -SEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDYGIMSESAY-------PYEAQGDYCRFD 214 Query: 191 VNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVE 250 + S +G D P S E + + + GPV Sbjct: 215 SSQSVTTLSGYYDLP---------------------------SGDENSLADAVGQAGPVA 247 Query: 251 GAFSVYSDFLLYKSGV-YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGF 309 A + Y G+ Y + H + ++G+G +NG YW++ NSW + WG++G+ Sbjct: 248 VAIDATDELQFYSGGLFYDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNSWGSGWGESGY 307 Query: 310 FKILRGQ-DHCGIESEVVAG 328 ++ +R ++CGI + Sbjct: 308 WRQVRNYGNNCGIATAASYP 327 >4YYW-A nrPDB Length = 220 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 105/257 (40%), Gaps = 45/257 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D W + IRDQG CGSCW F + + I T+ S+ S ++LL Sbjct: 1 LPETVD----WRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSL--SEQELL 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C S GC GG+ +A+++ +G+ S Y PY+ Sbjct: 55 DCAPSYKDLGCKGGWMDKAYDYIIKDRGITSESDY-------PYTARKGAC--------- 98 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 D+ K +++ S V +D + + N PV A S Sbjct: 99 ----DSRKATEVVATISSYE------------DVPADNEDALKKAVANQPVSVAIDASSA 142 Query: 259 -FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 Y SGV+ G HA+ ++G+G E+G YWLV NSW T WG+ G+ K+ R Sbjct: 143 AVKEYSSGVFVGSCGVA-NDHAVVVVGYGTESGVNYWLVRNSWGTKWGEEGYMKLERDTA 201 Query: 318 H----CGIESEVVAGIP 330 H CGI E + Sbjct: 202 HPAGKCGIAMESTYPVK 218 >3BCN-A nrPDB Length = 209 Score = 223 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 58/253 (22%), Positives = 86/253 (33%), Gaps = 48/253 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D W + +++QG CGSCWAF V + I T +S+ S + L+ Sbjct: 1 LPEHVD----WRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISL--SEQQLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C S GC GGY A+ + G + PY Sbjct: 55 DC--SKKNHGCKGGYFDRAYQYIIANGGID------TEANYPYKAFQGPCRAAKKVVRID 106 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 G P+C+ E + + V + F Sbjct: 107 GCKGVPQCN---------------------------ENALKNAVASQPSVVAIDASSKQF 139 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--GQD 317 YK G++ G + H + I+G+G YW+V NSW WG+ G+ ++ R G Sbjct: 140 QHYKGGIFTGPCGTKL-NHGVVIVGYG----KDYWIVRNSWGRHWGEQGYTRMKRVGGCG 194 Query: 318 HCGIESEVVAGIP 330 CGI Sbjct: 195 LCGIARLPFYPTK 207 >2VHS-A nrPDB Length = 217 Score = 223 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 65/253 (25%), Positives = 103/253 (40%), Gaps = 42/253 (16%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D RE+ + +++QG CG+ +AF A A+ ++ T +S+ S ++L+ Sbjct: 2 PRSVDWREK----GYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISL--SEQNLVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C G +GCNGG A+ + G + PY Sbjct: 56 CSGPQGNEGCNGGLMDYAFQYVQDNGGLDS------EESYPYEATEESC----------- 98 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSDF 259 Y+P Y G+ + EK +M + GP+ A + F Sbjct: 99 -------------KYNPKYSVANDVGF--VDIPKQEKALMKAVATVGPISVAIDAGHESF 143 Query: 260 LLYKSGVY-QHVTGEMMGGHAIRILGWG-VENGTPYWLVANSWNTDWGDNGFFKILRG-Q 316 L YK G+Y HA+ ++G+G + N YWLV NSW +WG G+ K+ + + Sbjct: 144 LFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKYWLVKNSWGEEWGMGGYVKMAKDRR 203 Query: 317 DHCGIESEVVAGI 329 +HCGI S Sbjct: 204 NHCGIASAASYPT 216 >1CQD-A nrPDB Length = 221 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 64/258 (24%), Positives = 103/258 (39%), Gaps = 46/258 (17%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 LP S D RE + +++QG CGSCWAF V A+ I T +S+ S + L Sbjct: 2 DLPDSIDWREN----GAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISL--SEQQL 55 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 + C + GC GG+ A+ F G ++ PY Sbjct: 56 VDC--TTANHGCRGGWMNPAFQFIVNNGGINS------EETYPY---------------- 91 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS- 257 G C+ +P D + +V + + + + N PV Sbjct: 92 --RGQDGICNSTVN---APVVSIDSYE-----NVPSHNEQSLQKAVANQPVSVTMDAAGR 141 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG-- 315 DF LY+SG++ + HA+ ++G+G EN +W+V NSW +WG++G+ + R Sbjct: 142 DFQLYRSGIFTGSCN-ISANHALTVVGYGTENDKDFWIVKNSWGKNWGESGYIRAERNIE 200 Query: 316 --QDHCGIESEVVAGIPR 331 CGI + + Sbjct: 201 NPDGKCGITRFASYPVKK 218 >2ACT-A nrPDB Length = 220 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 66/256 (25%), Positives = 107/256 (41%), Gaps = 44/256 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ D W + +I+ QG CG CWAF A+ + I + + +S+ S ++L+ Sbjct: 1 LPSYVD----WRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISL--SEQELI 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GC+GGY + + F G + + PY+ + V Sbjct: 55 DCGRTQNTRGCDGGYITDGFQFIINDGGI------NTEENYPYTAQDGDCDV-------- 100 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSY-SVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 + K+ ++Y +V + + + PV A D Sbjct: 101 ------------------ALQDQKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGD 142 Query: 259 -FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--- 314 F Y SG++ G + HAI I+G+G E G YW+V NSW+T WG+ G+ +ILR Sbjct: 143 AFKQYASGIFTGPCGTAV-DHAIVIVGYGTEGGVDYWIVKNSWDTTWGEEGYMRILRNVG 201 Query: 315 GQDHCGIESEVVAGIP 330 G CGI + + Sbjct: 202 GAGTCGIATMPSYPVK 217 >2PNS-A nrPDB Length = 208 Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 56/253 (22%), Positives = 85/253 (33%), Gaps = 48/253 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D W + + +++QG CGSCWAF V + I T +S+ S + L+ Sbjct: 1 LPEQID----WRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISL--SEQQLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GC GG A+ + G + PY Sbjct: 55 DC--NKKNHGCKGGAFVYAYQYIIDNGGID------TEANYPYKAVQGPCRAAKKVVRID 106 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 G P C+ E + + V + F Sbjct: 107 GYKGVPHCN---------------------------ENALKKAVASQPSVVAIDASSKQF 139 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--GQD 317 YKSG++ G + H + I+G+ YW+V NSW WG+ G+ ++ R G Sbjct: 140 QHYKSGIFSGPCGTKL-NHGVVIVGYW----KDYWIVRNSWGRYWGEQGYIRMKRVGGCG 194 Query: 318 HCGIESEVVAGIP 330 CGI Sbjct: 195 LCGIARLPYYPTK 207 >1YAL-A nrPDB Length = 218 Score = 220 bits (561), Expect = 5e-58, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 104/256 (40%), Gaps = 46/256 (17%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D W + +++QG+CGSCWAF + + I T +E+S ++L+ Sbjct: 2 PQSID----WRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNL--LELSEQELVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GC GGY + + G+ + +Y PY Sbjct: 56 C--DKHSYGCKGGYQTTSLQYVANNGVHTSKVY-------PYQA---------------- 90 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS-DF 259 KC +PG + K GY SN E + + N P+ F Sbjct: 91 --KQYKCRATDKPG-----PKVKITGYKRVP-SNCETSFLGALA-NQPLSVLVEAGGKPF 141 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 LYKSGV+ G + HA+ +G+G +G Y ++ NSW +WG+ G+ ++ R + Sbjct: 142 QLYKSGVFDGPCGTKL-DHAVTAVGYGTSDGKNYIIIKNSWGPNWGEKGYMRLKRQSGN- 199 Query: 320 GIESEVVAGIPRTDQY 335 S+ G+ ++ Y Sbjct: 200 ---SQGTCGVYKSSYY 212 >1IWD-A nrPDB Length = 215 Score = 218 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 58/255 (22%), Positives = 91/255 (35%), Gaps = 45/255 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ D W + I++Q CGSCWAF AV A+ I T +S+ S ++L+ Sbjct: 1 LPSFVD----WRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISL--SEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GCNGG+ A+ + G + PYS Sbjct: 55 DC--DTASHGCNGGWMNNAFQYIITNGGID------TQQNYPYSAVQGSCK--------- 97 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 P + N+E + + + + + F Sbjct: 98 -----------------PYRLRVVSINGFQRVTRNNESALQSAVASQPVSVTVEAAGAPF 140 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG---- 315 Y SG++ G H + I+G+G ++G YW+V NSW +WG+ G+ + R Sbjct: 141 QHYSSGIFTGPCGTA-QNHGVVIVGYGTQSGKNYWIVRNSWGQNWGNQGYIWMERNVASS 199 Query: 316 QDHCGIESEVVAGIP 330 CGI Sbjct: 200 AGLCGIAQLPSYPTK 214 >5JA7-A nrPDB Length = 223 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 64/258 (24%), Positives = 107/258 (41%), Gaps = 44/258 (17%) Query: 75 TEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVS 134 + + P S D R++ + +++QG CGS WAF +V A+ ++ T + +S Sbjct: 4 EWEGRAPDSVDYRKK----GYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKL--LNLS 57 Query: 135 AEDLLTCCGSMCGDGCNGGYPAEAWNFWTRK-GLVSGGLYESHVGCRPYSIPPCEHHVNG 193 ++L+ C DGC GGY A+ + + G+ S Y Sbjct: 58 PQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAY-------------------- 95 Query: 194 SRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAF 253 P + Y+PT K K GY N EK + + + GPV A Sbjct: 96 -----------PYVGQEESCMYNPTGKAAKCRGYREIPEGN-EKALKRAVARVGPVSVAI 143 Query: 254 SVY-SDFLLYKSGV-YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFK 311 + F Y GV Y HA+ +G+G++ G +W++ NSW +WG+ G+ Sbjct: 144 DASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYIL 203 Query: 312 ILRGQDH-CGIESEVVAG 328 + R +++ CGI + Sbjct: 204 MARNKNNACGIANLASFP 221 >1O0E-A nrPDB Length = 208 Score = 216 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 56/253 (22%), Positives = 86/253 (33%), Gaps = 48/253 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D W + + +++QGSCGSCWAF V + I T +S+ S ++L+ Sbjct: 1 LPEQID----WRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISL--SEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GC GG A+ + G + PY Sbjct: 55 DC--DKKNHGCLGGAFVFAYQYIINNGGID------TQANYPYKAVQGPCQAASKVVSID 106 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 G P C+ E + + + + F Sbjct: 107 GYNGVPFCN---------------------------EXALKQAVAVQPSTVAIDASSAQF 139 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR--GQD 317 Y SG++ G + H + I+G+ YW+V NSW WG+ G+ ++LR G Sbjct: 140 QQYSSGIFSGPCGTKL-NHGVTIVGYQ----ANYWIVRNSWGRYWGEKGYIRMLRVGGCG 194 Query: 318 HCGIESEVVAGIP 330 CGI Sbjct: 195 LCGIARLPYYPTK 207 >6BKI-A nrPDB Length = 215 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 59/252 (23%), Positives = 103/252 (40%), Gaps = 42/252 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +P S D R++ + +++QG CGSCWAF + A+ ++ T + +S ++L+ Sbjct: 1 VPDSIDYRKK----GYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKL--LALSPQNLV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GC GGY A+ + + G + PY Sbjct: 55 DCVTE--NYGCGGGYMTTAFQYVQQNGGIDS------EDAYPYVGQDESCM--------- 97 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY-SD 258 Y+ K K GY V N EK + + + GP+ + + Sbjct: 98 ---------------YNAAAKAAKCRGYREIPVGN-EKALKRAVARVGPISVSIDASLAS 141 Query: 259 FLLYKSGVYQHVTGEMMG-GHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 F Y GVY + HA+ ++G+G + G+ +W++ NSW WG+ G+ + R ++ Sbjct: 142 FQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKN 201 Query: 318 H-CGIESEVVAG 328 + CGI + Sbjct: 202 NACGITNMASFP 213 >1PPO-A nrPDB Length = 216 Score = 213 bits (543), Expect = 7e-56, Method: Composition-based stats. Identities = 67/256 (26%), Positives = 99/256 (38%), Gaps = 44/256 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D W + + +R QGSCGSCWAF AV + I T V E+S ++L+ Sbjct: 1 LPENVD----WRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLV--ELSEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GC GGYP A + + G+ Y PY P Sbjct: 55 DC--ERRSHGCKGGYPPYALEYVAKNGIHLRSKY-------PYKAKQGTCRAKQVGGPIV 105 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 + N+E +++ I K S F Sbjct: 106 KTSGVGRVQ------------------------PNNEGNLLNAIAKQPVSVVVESKGRPF 141 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 LYK G+++ G + HA+ +G+G G Y L+ NSW T WG+ G+ +I R + Sbjct: 142 QLYKGGIFEGPCGTKV-DHAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAPGN- 199 Query: 320 GIESEVVAGIPRTDQY 335 S V G+ ++ Y Sbjct: 200 ---SPGVCGLYKSSYY 212 >3F75-A nrPDB Length = 224 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 55/256 (21%), Positives = 90/256 (35%), Gaps = 41/256 (16%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP+ A W + ++DQ CGSCWAF A+ C T VS+ S ++L+ Sbjct: 3 LPSELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSL--SEQELM 60 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + C+GG +A+ + G + PY E Sbjct: 61 DCSRAEGNQSCSGGEMNDAFQYVLDSGGI------CSEDAYPYLARDEECRAQS------ 108 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS-D 258 C K+ + V + M PV A Sbjct: 109 -------CEKVVKI-------------LGFKDVPRRSEAAMKAALAKSPVSIAIEADQMP 148 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGV--ENGTPYWLVANSWNTDWGDNGFFKILRGQ 316 F Y GV+ G + H + ++G+G E+ +W++ NSW T WG +G+ + + Sbjct: 149 FQFYHEGVFDASCGTDL-DHGVLLVGYGTDKESKKDFWIMKNSWGTGWGRDGYMYMAMHK 207 Query: 317 ---DHCGIESEVVAGI 329 CG+ + + Sbjct: 208 GEEGQCGLLLDASFPV 223 >6MIS-A nrPDB Length = 215 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 66/256 (25%), Positives = 106/256 (41%), Gaps = 49/256 (19%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +P S D W + +++QG CGSCWAF ++ + I VS+ S + +L Sbjct: 1 VPQSID----WRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSL--SEQQVL 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C S GC GG+ +A++F KG+ S +Y PY NG Sbjct: 55 DCAVSY---GCKGGWINKAYSFIISNKGVASAAIY-------PYKAAKGTCKTNG----- 99 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 + +Y N+E+++M + N P+ A + Sbjct: 100 --------------------VPNSAYITRYTYVQRNNERNMMYAV-SNQPIAAALDASGN 138 Query: 259 FLLYKSGVYQHVTGEMMGGHAIRILGWGVE-NGTPYWLVANSWNTDWGDNGFFKILRGQ- 316 F YK GV+ G + HAI I+G+G + +G +W+V NSW WG+ G+ ++ R Sbjct: 139 FQHYKRGVFTGPCGTRL-NHAIVIIGYGQDSSGKKFWIVRNSWGAGWGEGGYIRLARDVS 197 Query: 317 ---DHCGIESEVVAGI 329 CGI + + Sbjct: 198 SSFGLCGIAMDPLYPT 213 >6EXO-A nrPDB Length = 215 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 62/249 (24%), Positives = 105/249 (42%), Gaps = 37/249 (14%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PA+ D RE+ + ++DQG CGSCWAF + I + + N VS+ S + L++ Sbjct: 2 PAAVDWREK----GAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSL--SEQMLVS 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GC GG A+N+ S P +G Sbjct: 56 C--DTIDFGCGGGLMDNAFNWIVNSNG-------------------GNVFTEASYPYVSG 94 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 G+ P+C + + + E I A + +NGP+ A S F+ Sbjct: 95 NGEQPQCQMNGH--------EIGAAITDHVDLPQDEDAIAAYLAENGPLAIAVDATS-FM 145 Query: 261 LYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320 Y G+ T E + H + ++G+ + PYW++ NSW+ WG++G+ +I +G + C Sbjct: 146 DYNGGILTSCTSEQL-DHGVLLVGYNDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCL 204 Query: 321 IESEVVAGI 329 + V + + Sbjct: 205 MNQAVSSAV 213 >2BDZ-A nrPDB Length = 214 Score = 211 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 60/254 (23%), Positives = 92/254 (36%), Gaps = 48/254 (18%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D RE+ + +++Q CGSCWAF V I I T +S+ S ++LL Sbjct: 2 PESIDWREK----GAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISL--SEQELLD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GC+GGY + + G+ + Y PY + P Sbjct: 56 C--ERRSHGCDGGYQTTSLQYVVDNGVHTEREY-------PYEKKQGRCRAKDKKGP--- 103 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 + Y +N E ++ I S F Sbjct: 104 ---------------------KVYITGYKYVPANDEISLIQAIANQPVSVVTDSRGRGFQ 142 Query: 261 LYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG----Q 316 YK G+Y+ G HA+ +G+G Y L+ NSW +WG+ G+ +I R + Sbjct: 143 FYKGGIYEGPCGTNT-DHAVTAVGYG----KTYLLLKNSWGPNWGEKGYIRIKRASGRSK 197 Query: 317 DHCGIESEVVAGIP 330 CG+ + I Sbjct: 198 GTCGVYTSSFFPIK 211 >2CIO-A nrPDB Length = 212 Score = 210 bits (535), Expect = 6e-55, Method: Composition-based stats. Identities = 68/255 (26%), Positives = 99/255 (38%), Gaps = 48/255 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +P D W Q + +++QGSCGSCWAF AV I I I T + S ++LL Sbjct: 1 IPEYVD----WRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNL--NQYSEQELL 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GCNGGYP A + G+ Y PY G + C Sbjct: 55 DC--DRRSYGCNGGYPWSALQLVAQYGIHYRNTY-------PY---------EGVQRYCR 96 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 P +K Y +E ++ I + DF Sbjct: 97 SREKGPYAAKTDGVRQVQPY---------------NEGALLYSIANQPVSVVLEAAGKDF 141 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDH- 318 LY+ G++ G + HA+ +G+G Y L+ NSW T WG+NG+ +I RG + Sbjct: 142 QLYRGGIFVGPCGNKV-DHAVAAVGYG----PNYILIKNSWGTGWGENGYIRIKRGTGNS 196 Query: 319 ---CGIESEVVAGIP 330 CG+ + + Sbjct: 197 YGVCGLYTSSFYPVK 211 >4YYQ-A nrPDB Length = 217 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 72/258 (27%), Positives = 105/258 (40%), Gaps = 47/258 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP + D W + IR+QG CGSCWAF AV A+ I T +S+ Sbjct: 1 LPETVD----WRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLL-- 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRK-GLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C S GC GG+ +A+ + + G+ S Y PY+ + Sbjct: 55 DCAQSYKNLGCQGGWVNKAFEYIIQNRGITSQSNY-------PYTGHKGQ---------- 97 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 C G + D + Y SN+E + + N PV A Sbjct: 98 ------------CRTGLASIATIDSYQ----YVPSNNENALKNAVA-NQPVSVAVEAAGR 140 Query: 259 -FLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRG-- 315 F LYKSGV+ G + HA+ ++G+G NG YWL+ NSW T+WG+ G+ K+ R Sbjct: 141 AFQLYKSGVFTGSCGVAI-DHAVVLIGYGKYNGVDYWLLRNSWGTNWGEQGYMKLQRNVA 199 Query: 316 --QDHCGIESEVVAGIPR 331 CG+ + + Sbjct: 200 QSAGKCGVARLCLYPVKC 217 >4PI3-A nrPDB Length = 216 Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 108/249 (43%), Gaps = 37/249 (14%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PA+ D W + ++DQG CGSCWAF A+ + + + H +S + L++ Sbjct: 3 PAAVD----WRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLA--GHPLTNLSEQMLVS 56 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GC+GG A+ + ++ +G +Y S P +G Sbjct: 57 C--DKTDSGCSGGLMNNAFEWIVQEN--NGAVYTED-----------------SYPYASG 95 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 EG +P C+ G++ H + E I A + NGPV A S ++ Sbjct: 96 EGISPPCT---TSGHTVGATITGH-----VELPQDEAQIAAWLAVNGPVAVAVDASS-WM 146 Query: 261 LYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG 320 Y GV E + H + ++G+ PYW++ NSW T WG+ G+ +I +G + C Sbjct: 147 TYTGGVMTSCVSEQL-DHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCL 205 Query: 321 IESEVVAGI 329 ++ E + + Sbjct: 206 VKEEASSAV 214 >1GEC-E nrPDB Length = 216 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 64/256 (25%), Positives = 96/256 (37%), Gaps = 44/256 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP S D W + ++ QG C SCWAF V + I T V E+S ++L+ Sbjct: 1 LPESVD----WRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLV--ELSEQELV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C + GCN GY + + + + G+ Y PY N P Sbjct: 55 DC--DLQSYGCNRGYQSTSLQYVAQNGIHLRAKY-------PYIAKQQTCRANQVGGPKV 105 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 + SN+E ++ I S DF Sbjct: 106 KTNGVGRVQ------------------------SNNEGSLLNAIAHQPVSVVVESAGRDF 141 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHC 319 YK G+++ G + HA+ +G+G G Y L+ NSW WG+NG+ +I R + Sbjct: 142 QNYKGGIFEGSCGTKV-DHAVTAVGYGKSGGKGYILIKNSWGPGWGENGYIRIRRASGN- 199 Query: 320 GIESEVVAGIPRTDQY 335 S V G+ R+ Y Sbjct: 200 ---SPGVCGVYRSSYY 212 >2B1M-A nrPDB Length = 246 Score = 201 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 57/260 (21%), Positives = 95/260 (36%), Gaps = 40/260 (15%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S+D W + I +++ QG CGS WAF A AI I T VS+ S ++L+ Sbjct: 3 PESWD----WSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSL--SEQELID 56 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C +GC G+ +++ + + G ++ PY + N + T Sbjct: 57 CVDE--SEGCYNGWHYQSFEWVVKHGGIAS------EADYPYKARDGKCKANEIQDKVTI 108 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 + + + P+ + DF Sbjct: 109 DNYGVQILSNESTESEAESS-------------------LQSFVLEQPISVSIDA-KDFH 148 Query: 261 LYKSGVYQH--VTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDH 318 Y G+Y + H + I+G+G E+G YW+ NSW DWG +G+ +I R + Sbjct: 149 FYSGGIYDGGNCSSPYGINHFVLIVGYGSEDGVDYWIAKNSWGEDWGIDGYIRIQRNTGN 208 Query: 319 ----CGIESEVVAGIPRTDQ 334 CG+ I + Sbjct: 209 LLGVCGMNYFASYPIIEKSE 228 >5A24-A nrPDB Length = 222 Score = 200 bits (508), Expect = 7e-52, Method: Composition-based stats. Identities = 64/258 (24%), Positives = 97/258 (37%), Gaps = 45/258 (17%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +PA+ D W + +++Q CG CWAF AV AI I T S+ S E ++ Sbjct: 1 VPAAVD----WRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSL--SEEQIV 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRK-GLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 C + GCNGG P A+ + G+ + Y P Sbjct: 55 DCDTNGNDKGCNGGTPDGAFQYVVNNQGIDTESDY----------------------PYT 92 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYS- 257 G G CS Y P + V + + + + P+ A Sbjct: 93 AGGGSPGTCSA---SSYQPAASITGYQ-----DVPANNEQALQQAAATQPISVAIDASDP 144 Query: 258 DFLLYKSGVYQHVTGEMMGGHAIRILGWGVE--NGTPYWLVANSWNTDWGDNGFFKILRG 315 F Y SG+Y + HA+ ++G+G + +G YW+V NSW T WG G+ + G Sbjct: 145 SFQSYSSGIYSGPCNTNL-DHAVTVVGYGTDPNSGNSYWIVKNSWGTSWGQEGYIWMQMG 203 Query: 316 QDH----CGIESEVVAGI 329 + CGI + Sbjct: 204 LNAPYGVCGIAMQASYPT 221 >5VPK-A nrPDB Length = 223 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 63/250 (25%), Positives = 93/250 (37%), Gaps = 40/250 (16%) Query: 76 EDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSA 135 + +P+ D R T+ IR QG CGSCWAF V A + N S+++S Sbjct: 7 NSVNVPSELDLR----SLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRN--TSLDLSE 60 Query: 136 EDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSR 195 ++L+ C GC+G + + G+V Y P R Sbjct: 61 QELVDCASQ---HGCHGDTIPRGIEYIQQNGVVEERSY-----------PYVAREQQCRR 106 Query: 196 PPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255 P G + C Y P KQ ++ + + + V Sbjct: 107 PNSQHYGISNYCQI-----YPPDVKQ--------------IREALTQTHTAIAVIIGIKD 147 Query: 256 YSDFLLYKS-GVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 314 F Y + QH G HA+ I+G+G G YW+V NSW+T WGD+G+ Sbjct: 148 LRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGVDYWIVRNSWDTTWGDSGYGYFQA 207 Query: 315 GQDHCGIESE 324 G + IE Sbjct: 208 GNNLMMIEQY 217 >3BPF-A nrPDB Length = 241 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 59/263 (22%), Positives = 107/263 (40%), Gaps = 53/263 (20%) Query: 82 ASFD-AREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 +FD A W + ++DQ +CGSCWAF ++ ++ + I N +++ S ++L+ Sbjct: 15 ENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITL--SEQELVD 72 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C S GCNGG A+ G + Sbjct: 73 C--SFKNYGCNGGLINNAFEDMIELGGI------------------------------CP 100 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 +GD P S P + + YG +Y +S + + + GP+ + +V DF Sbjct: 101 DGDYPYVSD--APNLCNIDRCTEKYGIKNY-LSVPDNKLKEALRFLGPISISVAVSDDFA 157 Query: 261 LYKSGVYQHVTGEMMGGHAIRILGWGVENGTP----------YWLVANSWNTDWGDNGFF 310 YK G++ G+ + HA+ ++G+G++ Y+++ NSW WG+ GF Sbjct: 158 FYKEGIFDGECGDQL-NHAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFI 216 Query: 311 KILRGQD----HCGIESEVVAGI 329 I + CG+ ++ + Sbjct: 217 NIETDESGLMRKCGLGTDAFIPL 239 >1XKG-A nrPDB Length = 312 Score = 190 bits (481), Expect = 9e-49, Method: Composition-based stats. Identities = 65/313 (20%), Positives = 104/313 (33%), Gaps = 54/313 (17%) Query: 24 HPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKL--- 80 + V + A ++ ++ + K FL + + + DL Sbjct: 26 EAARKNFLESVKYVQSNGGAINHLSDLSLDEFKNR---FLMSAEAFEHLKTQFDLNAETN 82 Query: 81 --------PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVE 132 PA D R Q T+ IR QG CGS WAF V A + + S++ Sbjct: 83 ACSINGNAPAEIDLR----QMRTVTPIRMQGGCGSAWAFSGVAATESAYLAYRDQ--SLD 136 Query: 133 VSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVN 192 ++ ++L+ C GC+G + G+V Y + Sbjct: 137 LAEQELVDCASQ---HGCHGDTIPRGIEYIQHNGVVQESYY-----------RYVAREQS 182 Query: 193 GSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGA 252 RP G + C +N ++ +A+ + V Sbjct: 183 CRRPNAQRFGISNYCQIYP-------------------PNANKIREALAQTHSAIAVIIG 223 Query: 253 FSVYSDFLLYKS-GVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFK 311 F Y + Q G HA+ I+G+ G YW+V NSW+T+WGDNG+ Sbjct: 224 IKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGY 283 Query: 312 ILRGQDHCGIESE 324 D IE Sbjct: 284 FAANIDLMMIEEY 296 >3IOQ-A nrPDB Length = 213 Score = 190 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 58/255 (22%), Positives = 93/255 (36%), Gaps = 48/255 (18%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 +P S D W Q + +R+QG CGSCW F +V A+ I T +S+ Sbjct: 1 IPTSID----WRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELL-- 54 Query: 140 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 199 C GC GG+P A + G+ Y PY + + ++ P Sbjct: 55 DC--ERRSYGCRGGFPLYALQYVANSGIHLRQYY-------PYEGVQRQCRASQAKGPKV 105 Query: 200 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDF 259 + N+E+ ++ I + F Sbjct: 106 KTDGVGR------------------------VPRNNEQALIQRIAIQPVSIVVEAKGRAF 141 Query: 260 LLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDH- 318 Y+ G++ G + HA+ +G+G Y L+ NSW T WG+ G+ +I RG + Sbjct: 142 QNYRGGIFAGPCGTSI-DHAVAAVGYGN----DYILIKNSWGTGWGEGGYIRIKRGSGNP 196 Query: 319 ---CGIESEVVAGIP 330 CG+ S+ V Sbjct: 197 QGACGVLSDSVFPTK 211 >5VCN-A nrPDB Length = 222 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 60/247 (24%), Positives = 88/247 (35%), Gaps = 40/247 (16%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 PA D R Q T+ IR QG CGSCWAF V A + N S++++ ++L Sbjct: 9 NAPAEIDLR----QMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQ--SLDLAEQEL 62 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPC 198 + C GC+G + G+V Y + RP Sbjct: 63 VDCASQ---HGCHGDTIPRGIEYIQHNGVVQESYY-----------RYVAREQSCRRPNA 108 Query: 199 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSD 258 G + C +N ++ +A+ + V Sbjct: 109 QRFGISNYCQIYP-------------------PNANKIREALAQTHSAIAVIIGIKDLDA 149 Query: 259 FLLYKS-GVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 F Y + Q G HA+ I+G+ G YW+V NSW+T+WGDNG+ D Sbjct: 150 FRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANID 209 Query: 318 HCGIESE 324 IE Sbjct: 210 LMMIEEY 216 >3BPM-A nrPDB Length = 243 Score = 184 bits (466), Expect = 6e-47, Method: Composition-based stats. Identities = 55/257 (21%), Positives = 97/257 (37%), Gaps = 52/257 (20%) Query: 87 REQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMC 146 W + ++DQ CGSCWAF +V ++ + I A S ++L+ C S+ Sbjct: 23 AYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKAL--FLFSEQELVDC--SVK 78 Query: 147 GDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPK 206 +GC GGY A++ G + PY Sbjct: 79 NNGCYGGYITNAFDDMIDLGGL------CSQDDYPYV----------------------- 109 Query: 207 CSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV 266 P + ++ Y SY VS + + GP+ + + DF Y+ G Sbjct: 110 ---SNLPETCNLKRCNERYTIKSY-VSIPDDKFKEALRYLGPISISIAASDDFAFYRGGF 165 Query: 267 YQHVTGEMMGGHAIRILGWGVEN----------GTPYWLVANSWNTDWGDNGFFKILRGQ 316 Y G HA+ ++G+G+++ Y+++ NSW +DWG+ G+ + + Sbjct: 166 YDGECG-AAPNHAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDE 224 Query: 317 D----HCGIESEVVAGI 329 + C I +E + Sbjct: 225 NGYKKTCSIGTEAYVPL 241 >1ICF-A nrPDB Length = 175 Score = 183 bits (465), Expect = 7e-47, Method: Composition-based stats. Identities = 51/211 (24%), Positives = 82/211 (38%), Gaps = 40/211 (18%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P S D RE+ + +++QG CGSCWAF A A+ ++ T +S+ S ++L+ Sbjct: 2 PRSVDWREK----GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISL--SEQNLVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C G +GCNGG A+ + G + PY Sbjct: 56 CSGPQGNEGCNGGLMDYAFQYVQDNGGLDS------EESYPYEATEESC----------- 98 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSDF 259 Y+P Y G+ + EK +M + GP+ A + F Sbjct: 99 -------------KYNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAGHESF 143 Query: 260 LLYKSGVY-QHVTGEMMGGHAIRILGWGVEN 289 L YK G+Y + H + ++G+G E+ Sbjct: 144 LFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 174 >1M6D-A nrPDB Length = 214 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 53/252 (21%), Positives = 100/252 (39%), Gaps = 44/252 (17%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 P +D W + +++DQG CGSCWAF + + ++ +S+ Sbjct: 2 PPEWD----WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELL--D 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C C GG P+ A++ G + ++ G C Sbjct: 56 C--DKMDKACMGGLPSNAYSAIKNLGGLE---------------TEDDYSYQGHMQSCQF 98 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 + K Y +S +S +E+ + A + K GP+ A + + Sbjct: 99 SAEKAKV-----------------YIQDSVELSQNEQKLAAWLAKRGPISVAINAFG-MQ 140 Query: 261 LYKSGV---YQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQD 317 Y+ G+ + + + HA+ ++G+G + P+W + NSW TDWG+ G++ + RG Sbjct: 141 FYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVPFWAIKNSWGTDWGEKGYYYLHRGSG 200 Query: 318 HCGIESEVVAGI 329 CG+ + + + Sbjct: 201 ACGVNTMASSAV 212 >4OEL-A nrPDB Length = 370 Score = 183 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 70/266 (26%), Positives = 109/266 (40%), Gaps = 41/266 (15%) Query: 14 LANARSRPSFHPLS--DELVNYVNKRNTTWQAG--HNFYNVDMSYLKRLCG-----TFLG 64 L N++ + S V +N +W A + + + + R G Sbjct: 132 LKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRP 191 Query: 65 GPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 124 P P + + L LP S+D R + +R+Q SCGSC++F ++ + RI I Sbjct: 192 KPAPLTAEIQQKILHLPTSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRIL 250 Query: 125 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPA-EAWNFWTRKGLVSGGLYESHVGCRPYS 183 TN + +S +++++C S GC GG+P A + GLV C PY+ Sbjct: 251 TNNSQTPILSPQEVVSC--SQYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT 301 Query: 184 IPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEI 243 G+ PC + D + Y + HY Y N E + E+ Sbjct: 302 ---------GTDSPCKMKEDCFR-----------YYSSEYHYVGGFYGGCN-EALMKLEL 340 Query: 244 YKNGPVEGAFSVYSDFLLYKSGVYQH 269 +GP+ AF VY DFL YK G+Y H Sbjct: 341 VHHGPMAVAFEVYDDFLHYKKGIYHH 366 >3U8E-A nrPDB Length = 222 Score = 182 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 59/262 (22%), Positives = 97/262 (37%), Gaps = 50/262 (19%) Query: 81 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 140 PAS D W + + ++DQG+CG CWAFGA AI I T +SV S + ++ Sbjct: 2 PASID----WRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISV--SEQQIVD 55 Query: 141 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 200 C GG +A+ + G ++ PY+ Sbjct: 56 CDTXXXXX--XGGDADDAFRWVITNGGIASD------ANYPYTGVDG------------- 94 Query: 201 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFL 260 C+ + D + +V NS ++ + K ++ + F Sbjct: 95 ---------TCDLNKPIAARIDGYT-----NVPNSSSALLDAVAKQPVSVNIYTSSTSFQ 140 Query: 261 LYKS-GVYQHVTG---EMMGGHAIRILGWGVEN-GTPYWLVANSWNTDWGDNGFFKILRG 315 LY G++ + H + I+G+G YW+V NSW T+WG +G+ I R Sbjct: 141 LYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTNADYWIVKNSWGTEWGIDGYILIRRN 200 Query: 316 QDH----CGIESEVVAGIPRTD 333 + C I++ T Sbjct: 201 TNRPDGVCAIDAWGSYPTKSTS 222 >1DEU-A nrPDB Length = 277 Score = 174 bits (440), Expect = 6e-44, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 100/256 (39%), Gaps = 29/256 (11%) Query: 63 LGGPKPPQRVMFTEDLKLPASFDARE-QWPQCPTIKEIRDQ---GSCGSCWAFGAVEAIS 118 LG P+ + LP S+D R +I R+Q CGSCWA + A++ Sbjct: 19 LGRTTYPRPHEYLSPADLPKSWDWRNVDGVNYASIT--RNQHIPQYCGSCWAHASTSAMA 76 Query: 119 DRICI-HTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHV 177 DRI I A S +S ++++ C C GG W++ + G+ Sbjct: 77 DRINIKRKGAWPSTLLSVQNVIDCG---NAGSCEGGNDLSVWDYAHQHGI-------PDE 126 Query: 178 GCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEK 237 C Y E C K C + T + YG S + Sbjct: 127 TCNNYQAKDQECDKFNQCGTCNEF-------KECHAIRNYTLWRVGDYGSLS-----GRE 174 Query: 238 DIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVA 297 +MAEIY NGP+ Y G+Y H + + GWG+ +GT YW+V Sbjct: 175 KMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVR 234 Query: 298 NSWNTDWGDNGFFKIL 313 NSW WG+ G+ +I+ Sbjct: 235 NSWGEPWGERGWLRIV 250 >1EF7-A nrPDB Length = 242 Score = 167 bits (422), Expect = 7e-42, Method: Composition-based stats. Identities = 64/238 (26%), Positives = 93/238 (39%), Gaps = 27/238 (11%) Query: 80 LPASFDAREQWPQCPTIKEIRDQ---GSCGSCWAFGAVEAISDRICI-HTNAHVSVEVSA 135 LP S+D R R+Q CGSCWA + A++DRI I A S +S Sbjct: 1 LPKSWDWRNV-DGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 59 Query: 136 EDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSR 195 ++++ C C GG W++ + G+ C Y E Sbjct: 60 QNVIDCG---NAGSCEGGNDLSVWDYAHQHGI-------PDETCNNYQAKDQECDKFNQC 109 Query: 196 PPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV 255 C K C + T + YG S + +MAEIY NGP+ Sbjct: 110 GTCNEF-------KECHAIRNYTLWRVGDYGSLS-----GREKMMAEIYANGPISCGIMA 157 Query: 256 YSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 313 Y G+Y H + + GWG+ +GT YW+V NSW WG+ G+ +I+ Sbjct: 158 TERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIV 215 >5JT8-A nrPDB Length = 333 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 83/323 (25%), Positives = 131/323 (40%), Gaps = 57/323 (17%) Query: 24 HPLSDEL--VNYVNKRNTTWQAGHNFYNVDMSYL------KRLCGTFLGGPKPPQRVMFT 75 H ++L V N + A + + ++ L T++ + ++ T Sbjct: 50 HHFKEQLKWVEEHNGIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINT 109 Query: 76 EDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSA 135 LP +FD R++ + IR QGSCGSCWAF A I S+E+S Sbjct: 110 YG-SLPQNFDWRQKAR----LTRIRQQGSCGSCWAFAAAGVAESLYSIQ--KQQSIELSE 162 Query: 136 EDLLTCC-----GSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPP--CE 188 ++L+ C S +GC GY EA+ + R GLV Y PY++ C+ Sbjct: 163 QELVDCTYNRYDPSYQCNGCGSGYSTEAFKYMIRTGLVEERNY-------PYNMRTQWCD 215 Query: 189 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 248 V G R +G S S++D+M I ++GP Sbjct: 216 PDVEGQRYHVSGYQQLRYHS--------------------------SDEDVMYTIQQHGP 249 Query: 249 VEGAFSVYSD-FLLYKSGVYQHVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306 V ++ F +GV + V + HA+ ++GWG G YW++ NSW T WG+ Sbjct: 250 VVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWGN 309 Query: 307 NGFFKILRGQDHCGIESEVVAGI 329 G+ + RG + GI + V Sbjct: 310 GGYGYVERGHNSLGINNYVTYAT 332 >3CH2-X nrPDB Length = 265 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 53/237 (22%), Positives = 89/237 (37%), Gaps = 16/237 (6%) Query: 92 QCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCN 151 C + ++ DQG+C + W F + + C+ + ++SA + C D C+ Sbjct: 17 NCISNLQVEDQGNCDTSWIFASKYHLETIRCMK--GYEPTKISALYVANCYKGEHKDRCD 74 Query: 152 -GGYPAEAWNFWTRKGLVS-GGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 209 G P E G + Y + P E H + + + Sbjct: 75 EGSSPMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNS 134 Query: 210 ICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGV-YQ 268 + GY+ + H +++ K I E+ G V + SG Q Sbjct: 135 LDGKGYTAYESERFHDNMDAFV-----KIIKTEVMNKGSVIAYIKAENVMGYEFSGKKVQ 189 Query: 269 HVTGEMMGGHAIRILGWGVE-----NGTPYWLVANSWNTDWGDNGFFKI-LRGQDHC 319 ++ G+ HA+ I+G+G YW+V NSW WGD G+FK+ + G HC Sbjct: 190 NLCGDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >4CDF-B nrPDB Length = 166 Score = 153 bits (387), Expect = 9e-38, Method: Composition-based stats. Identities = 59/193 (30%), Positives = 87/193 (45%), Gaps = 32/193 (16%) Query: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 L LP S+D R + +R+Q SCGSC++F ++ + RI I TN + +S ++ Sbjct: 1 LHLPTSWDWRNV-HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQE 59 Query: 138 LLTCCGSMCGDGCNGGYPA-EAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRP 196 +++C S GC GG+P A + GLV C PY+ G+ Sbjct: 60 VVSC--SQYAQGCEGGFPYLIAGKYAQDFGLVEEA-------CFPYT---------GTDS 101 Query: 197 PCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVY 256 PC + D + Y + HY Y N E + E+ +GP+ AF VY Sbjct: 102 PCKMKEDCFR-----------YYSSEYHYVGGFYGGCN-EALMKLELVHHGPMAVAFEVY 149 Query: 257 SDFLLYKSGVYQH 269 DFL YK G+Y H Sbjct: 150 DDFLHYKKGIYHH 162 >5I4H-A nrPDB Length = 106 Score = 125 bits (313), Expect = 4e-29, Method: Composition-based stats. Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 12/118 (10%) Query: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138 + P S D RE+ + +++QG CGS WAF A A+ ++ T +S+ S ++L Sbjct: 1 EAPRSVDWREK----GYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISL--SEQNL 54 Query: 139 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRP 196 + C G +GCNGG A+ + G + PY N Sbjct: 55 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS------EESYPYEATEESCKYNPKYS 106 >5I4H-B nrPDB Length = 112 Score = 124 bits (310), Expect = 8e-29, Method: Composition-based stats. Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Query: 228 NSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSDFLLYKSGVY-QHVTGEMMGGHAIRILGW 285 + EK +M + GP+ A + FL YK G+Y + H + ++G+ Sbjct: 3 GFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGY 62 Query: 286 GVE----NGTPYWLVANSWNTDWGDNGFFKILRG-QDHCGIESEVVAGI 329 G E + YWLV NSW +WG G+ K+ + ++HCGI S Sbjct: 63 GFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 111 >4OEM-B nrPDB Length = 70 Score = 98.7 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 28/62 (45%), Positives = 39/62 (62%), Gaps = 2/62 (3%) Query: 271 TGEMMGGHAIRILGWGVEN--GTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAG 328 + HA+ ++G+G ++ G YW+V NSW T WG+NG+F+I RG D C IES VA Sbjct: 4 NPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAA 63 Query: 329 IP 330 P Sbjct: 64 TP 65 >4CI7-A nrPDB Length = 470 Score = 68.7 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 37/281 (13%), Positives = 79/281 (28%), Gaps = 39/281 (13%) Query: 47 FYNVDMSYLKRLCGTFL-GGPKPPQRVMFTEDLKLPASFDAREQW--PQCPTIKEIRDQG 103 +V + G + LP+++ + + ++QG Sbjct: 25 LEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLGLTTPAKNQG 84 Query: 104 SCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWT 163 S + W+F + + + + + + ++S E L +W Sbjct: 85 SLNTAWSFSGMSTLEAYLKLK--GYGTYDLSEEHL---------------------RWWA 121 Query: 164 RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDK 223 G G + G + G + + ++ + + Sbjct: 122 -TGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQ 180 Query: 224 HYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRIL 283 + ++ ++ + I + G V ++ YS + Y HA+ I+ Sbjct: 181 FNVTDVVRLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIV 240 Query: 284 GWGVENGTP------------YWLVANSWNTDWGDNGFFKI 312 GW WLV +SW GFF I Sbjct: 241 GWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 281 >4D59-A nrPDB Length = 406 Score = 67.5 bits (163), Expect = 9e-12, Method: Composition-based stats. Identities = 33/231 (14%), Positives = 67/231 (29%), Gaps = 36/231 (15%) Query: 94 PTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGG 153 ++QGS + W+F + + + + + + ++S E L Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLK--GYGTYDLSEEHL--------------- 53 Query: 154 YPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEP 213 +W G G + G + G + + ++ Sbjct: 54 ------RWWA-TGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATK 106 Query: 214 GYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGE 273 + + + ++ ++ + I + G V ++ YS + Y Sbjct: 107 PSNMDTAPTQFNVTDVVRLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKR 166 Query: 274 MMGGHAIRILGWGVENGTP------------YWLVANSWNTDWGDNGFFKI 312 HA+ I+GW WLV +SW GFF I Sbjct: 167 APLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 217 >3OIS-A nrPDB Length = 291 Score = 60.2 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 43/242 (17%), Positives = 79/242 (32%), Gaps = 38/242 (15%) Query: 80 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 139 LP D + ++ DQG GSC A AI + S E L Sbjct: 57 LPPKVDLTPPF-------QVYDQGRIGSCTANALAAAIQ---FERIHDKQSPEFIPSRLF 106 Query: 140 TCCGSMCGDGC----NGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSR 195 +G +G + + G+ + PY P + Sbjct: 107 IYYNERKIEGHVNYDSGAMIRDGIKVLHKLGVCPEKEW-------PYGDTPADPRTEEFP 159 Query: 196 PPC-TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 254 P + + +C K + Y + V+ + A + P FS Sbjct: 160 PGAPASKKPSDQCYKDAQNYKITEYSR----------VAQDIDHLKACLAVGSPFVFGFS 209 Query: 255 VYSDFLLYKSGVYQHVTGEMMG----GHAIRILGWGVENGTPYWLVANSWNTDWGDNGFF 310 VY+ ++ S + GHA+ +G+ ++ ++ + NSW + G++G+F Sbjct: 210 VYNSWVGNNSLPVRIPLPTKNDTLEGGHAVLCVGY--DDEIRHFRIRNSWGNNVGEDGYF 267 Query: 311 KI 312 + Sbjct: 268 WM 269 >4K7C-A nrPDB Length = 446 Score = 44.4 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 272 GEMMGGHAIRILGWGVENGTPY-WLVANSWNTDWGDNGFF 310 GE + HA+ + G + +G P W V NSW G+ G+F Sbjct: 358 GESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 >5WDK-A nrPDB Length = 401 Score = 37.9 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 1/32 (3%) Query: 273 EMMGGHAIRILGWGVEN-GTPYWLVANSWNTD 303 E H ++I G + G Y++V NSW T+ Sbjct: 331 ETTDDHGMQIYGIAKDQEGNEYYMVKNSWGTN 362 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 5/37 (13%), Positives = 14/37 (37%) Query: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVE 132 I +++Q G+CW + + + + + Sbjct: 40 ITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLS 76 >2CB5-A nrPDB Length = 453 Score = 35.6 bits (80), Expect = 0.030, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 18/45 (40%), Gaps = 4/45 (8%) Query: 272 GEMMGGHAIRILGWGVENGTP----YWLVANSWNTDWGDNGFFKI 312 GE + HA+ ++ W V NSW D G G+ + Sbjct: 365 GESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCM 409 >2EKL-A nrPDB Length = 313 Score = 31.3 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 1/86 (1%) Query: 216 SPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMM 275 + ++ + + D E+ + A +Y+ L KSG+++ + G + Sbjct: 81 NIDTEEAEKRNIKVVYAPGASTDSAVELTIGLMIAAARKMYTSMALAKSGIFKKIEGLEL 140 Query: 276 GGHAIRILGWGVENGTPYWLVANSWN 301 G I I+G+G GT ++AN+ Sbjct: 141 AGKTIGIVGFG-RIGTKVGIIANAMG 165 >3N7B-A nrPDB Length = 338 Score = 30.9 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 23/74 (31%), Gaps = 6/74 (8%) Query: 13 VLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRV 72 V +NA+++ + + W + ++ + R + P Sbjct: 88 VDSNAKAKVAGDIF------EIVSSAVMWNCAARWNSLMVGEGWRSQPRYSRPTLSPSPR 141 Query: 73 MFTEDLKLPASFDA 86 L LP SFD Sbjct: 142 RQVAVLNLPRSFDW 155 >2Z51-A nrPDB Length = 154 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 6/15 (40%), Positives = 10/15 (66%) Query: 94 PTIKEIRDQGSCGSC 108 + ++ QG+CGSC Sbjct: 34 GNVVRVKLQGACGSC 48 >5O4O-C nrPDB Length = 649 Score = 28.2 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 28/82 (34%), Gaps = 14/82 (17%) Query: 82 ASFDAREQWPQCPTIKEIRDQG-SC--------GSCWAFGA--VEAISDRICIHTNAHVS 130 + D R+ ++D G SC G CW G+ + ++ IC Sbjct: 159 DTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHC 218 Query: 131 VEVSAEDLLTCCGSMCGDGCNG 152 + CC C GC+G Sbjct: 219 FGPNPNQ---CCHDECAGGCSG 237 >3P11-A nrPDB Length = 522 Score = 28.2 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 28/82 (34%), Gaps = 14/82 (17%) Query: 82 ASFDAREQWPQCPTIKEIRDQG-SC--------GSCWAFGA--VEAISDRICIHTNAHVS 130 + D R+ ++D G SC G CW G+ + ++ IC Sbjct: 140 DTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHC 199 Query: 131 VEVSAEDLLTCCGSMCGDGCNG 152 + CC C GC+G Sbjct: 200 FGPNPNQ---CCHDECAGGCSG 218 >5E9F-A nrPDB Length = 560 Score = 28.2 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 16/37 (43%), Gaps = 2/37 (5%) Query: 300 WNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYW 336 W++ G+F+I G D C I + P D W Sbjct: 369 WDSPRTREGYFRIKGGCD-CAINRAIAYA-PYADAIW 403 >5DDC-A nrPDB Length = 489 Score = 27.8 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 31/126 (24%), Gaps = 4/126 (3%) Query: 164 RKGLVSGGLYESHVGCRPYSIPPC-EHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQD 222 KG+ S Y PY R DT + Sbjct: 288 HKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYK 347 Query: 223 KHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTG-EMMGGHAIR 281 + + + + N K+ A + + G A F Y + E + Sbjct: 348 EFFEVANDVIPNLLKEA-ASLLEAGSQGSALQDPECFAHLLR-FYDGICKWEEGSPTPVL 405 Query: 282 ILGWGV 287 +GW Sbjct: 406 HVGWAT 411 >2CBT-A nrPDB Length = 112 Score = 27.5 bits (59), Expect = 9.7, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 18/31 (58%) Query: 270 VTGEMMGGHAIRILGWGVENGTPYWLVANSW 300 + + G +++ G G++ GT YW+ ++W Sbjct: 9 PSSGLSDGTVVKVAGAGLQAGTAYWVAQSAW 39 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.122 0.390 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,183,028 Number of Sequences: 36641 Number of extensions: 610951 Number of successful extensions: 1901 Number of sequences better than 10.0: 93 Number of HSP's better than 10.0 without gapping: 165 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1201 Number of HSP's gapped (non-prelim): 254 length of query: 339 length of database: 10,336,785 effective HSP length: 98 effective length of query: 241 effective length of database: 6,745,967 effective search space: 1625778047 effective search space used: 1625778047 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 59 (27.4 bits)