BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07824 (323 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5RLA-A nrPDB 655 0.0 3LP4-A nrPDB 577 e-165 1PQ3-A nrPDB 405 e-113 5YNL-A nrPDB 273 1e-73 4Q3T-A nrPDB 254 3e-68 1CEV-A nrPDB 237 5e-63 4ITY-A nrPDB 224 4e-59 6DKT-A nrPDB 219 1e-57 6NBK-A nrPDB 219 1e-57 2EF5-A nrPDB 203 7e-53 3SL1-A nrPDB 139 2e-33 4DZ4-A nrPDB 85 3e-17 1GQ7-A nrPDB 85 5e-17 3NIP-A nrPDB 78 5e-15 3PZL-A nrPDB 75 5e-14 4G3H-A nrPDB 74 8e-14 3NIO-A nrPDB 68 7e-12 4RHL-A nrPDB 66 2e-11 1WOG-A nrPDB 61 7e-10 3LHL-A nrPDB 58 5e-09 3M1R-A nrPDB 53 2e-07 1XFK-A nrPDB 36 0.027 4V4O-A nrPDB 32 0.25 1MQS-A nrPDB 31 0.68 4R3U-A nrPDB 31 0.85 1PZY-B nrPDB 30 1.3 1SJP-A nrPDB 30 1.9 3EWD-A nrPDB 29 2.5 4QKO-B nrPDB 29 2.6 2VWH-A nrPDB 29 3.1 3S2F-A nrPDB 29 3.6 4GYG-A nrPDB 28 3.7 1AC5-A nrPDB 28 6.8 1WOU-A nrPDB 28 7.0 3HP7-A nrPDB 28 7.3 4Z25-A nrPDB 27 8.3 2WZP-P nrPDB 27 8.5 >5RLA-A nrPDB Length = 323 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/323 (99%), Positives = 323/323 (100%) Query: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN Sbjct: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 Query: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCV 120 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGD+SMAIGSISGHARVHPDLCV Sbjct: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDNSMAIGSISGHARVHPDLCV 120 Query: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF Sbjct: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 Query: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT Sbjct: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 Query: 301 LSCFGTKREGNHKPETDYLKPPK 323 LSCFGTKREGNHKPETDYLKPPK Sbjct: 301 LSCFGTKREGNHKPETDYLKPPK 323 >3LP4-A nrPDB Length = 322 Score = 577 bits (1486), Expect = e-165, Method: Compositional matrix adjust. Identities = 281/323 (86%), Positives = 301/323 (93%), Gaps = 1/323 (0%) Query: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 MS+K + I IIGAPFSKGQPRGGVE+GP LRKAGL+EKLKE E +V+D+GDL F D+PN Sbjct: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 Query: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCV 120 DSPFQIVKNPRSVGKA+EQLA VAE +KNG IS+VLGGDHS+AIGSISGHARVHPDL V Sbjct: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 Query: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTT+SGNLHGQPV+FLLKELKGK PDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 DVDPGEHYI+KTLGIKYFSMTEVD+LGIGKVMEET SYLLGRKKRPIHLSFDVDGLDP F Sbjct: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 Query: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 TPATGTPVVGGL+YREGLYITEEIYKTGLLSGLDIMEVNP+LGKTPEEVTRTVNTAVA+T Sbjct: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 Query: 301 LSCFGTKREGNHKPETDYLKPPK 323 L+CFG REGNHKP DYL PPK Sbjct: 301 LACFGLAREGNHKP-IDYLNPPK 322 >1PQ3-A nrPDB Length = 306 Score = 405 bits (1041), Expect = e-113, Method: Compositional matrix adjust. Identities = 189/304 (62%), Positives = 235/304 (77%), Gaps = 1/304 (0%) Query: 8 IEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQ-I 66 + +IGAPFS+GQ R GVE GPAA+R+AGL+++L +++D GDL+F VP D + + Sbjct: 3 VAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNL 62 Query: 67 VKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAH 126 + NPRSVG AN++LA VV+ +G V LGGDHS+AIG+ISGHAR PDLCV+WVDAH Sbjct: 63 IVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAH 122 Query: 127 TDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGE 186 DINTPLTTSSGNLHGQPV+FLL+EL+ K P +PGFSW+ PCIS+ IVYIGLRDVDP E Sbjct: 123 ADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPPE 182 Query: 187 HYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGT 246 H+I+K I+YFSM ++D+LGI KVME TF L+G+++RPIHLSFD+D DP PATGT Sbjct: 183 HFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGT 242 Query: 247 PVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGT 306 PVVGGL+YREG+YI EEI+ TGLLS LD++EVNP L + EE T N AV + S FG Sbjct: 243 PVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQ 302 Query: 307 KREG 310 REG Sbjct: 303 TREG 306 >5YNL-A nrPDB Length = 362 Score = 273 bits (697), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 143/307 (46%), Positives = 191/307 (62%), Gaps = 5/307 (1%) Query: 3 SKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHG-DLAFVDVPND 61 + P+ I+G PFS GQP+ GV GP L ++GL+ ++ + V G D V + +D Sbjct: 53 ATPRTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSD 112 Query: 62 SP---FQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDL 118 +P +K PR V + + +A V G ++V LGGDHS+A+G++SG + +P+ Sbjct: 113 TPDPDIGRLKQPRLVSRVTKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKAYPEA 172 Query: 119 CVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIG 178 C+IWVDAH DINTP TT SG LHG PV+FLL ++P FSW+ PC+ + IVYIG Sbjct: 173 CLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGTSSEEIPEFSWIKPCLKPERIVYIG 232 Query: 179 LRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDP 238 LRD+D GE I+K IK FSM VDK GIGKV+E ++ + RPIHLSFDVD LDP Sbjct: 233 LRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVNPDRTRPIHLSFDVDALDP 292 Query: 239 VFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVA 298 P+TGT V GGL++REG YI E I +T LL LDIME+NP+LG V +TV+ + Sbjct: 293 SVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGAL-ASVAQTVDVGRS 351 Query: 299 LTLSCFG 305 L G Sbjct: 352 LVRCALG 358 >4Q3T-A nrPDB Length = 385 Score = 254 bits (649), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 136/326 (41%), Positives = 202/326 (61%), Gaps = 19/326 (5%) Query: 4 KPKPI----EIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVP 59 KPK + +G P ++GQP+ G +GP +RK+ + + E + D GD+ V++ Sbjct: 37 KPKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELN 96 Query: 60 N-DSPFQI-VKNPRSVGKANEQLAAVVAETQKNG------------TISVVLGGDHSMAI 105 + P + +K RS ++A V E K T V++GGDHSMA Sbjct: 97 EAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSKSTPLVIVGGDHSMAT 156 Query: 106 GSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWV 165 G+I GHA PDLCV+W+DAH DINTPL ++SGN+HG P++FL+KEL+ + P + F + Sbjct: 157 GTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGI 216 Query: 166 TPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKR 225 PC++A +I YIGLRD+D E + I+ GI YF+M +VD++GI V++E + R ++ Sbjct: 217 KPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEK 276 Query: 226 PIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKT 285 IHLSFD+D LDP+ P+TGT V GGL+ REGL I EE+ TG LS +++ E+NP LG + Sbjct: 277 AIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLG-S 335 Query: 286 PEEVTRTVNTAVALTLSCFGTKREGN 311 E+V +T ++AV + +C G R G+ Sbjct: 336 QEDVLKTQSSAVHILRACLGHCRSGH 361 >1CEV-A nrPDB Length = 299 Score = 237 bits (604), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 130/304 (42%), Positives = 189/304 (62%), Gaps = 10/304 (3%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAF--VDVPNDSP 63 KPI IIG P GQ R GV+ GP+A+R AG++E+L+ Y++ D GD+ + ++ Sbjct: 2 KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQG 61 Query: 64 FQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWV 123 ++N ++V +ANE+LAA V + + G +VLGGDHS+AIG+++G A+ + L VIW Sbjct: 62 DSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWY 121 Query: 124 DAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVD 183 DAH D+NT T+ SGN+HG P+A L + G+S P I + +V IG+R +D Sbjct: 122 DAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYS---PKIKPEHVVLIGVRSLD 178 Query: 184 PGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPA 243 GE I+ GIK ++M EVD+LG+ +VMEET +YL R +HLS D+DGLDP P Sbjct: 179 EGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTD-GVHLSLDLDGLDPSDAPG 237 Query: 244 TGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSC 303 GTPV+GGL+YRE E + + +++ + +EVNP L +E +T + AVAL S Sbjct: 238 VGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPIL----DERNKTASVAVALMGSL 293 Query: 304 FGTK 307 FG K Sbjct: 294 FGEK 297 >4ITY-A nrPDB Length = 330 Score = 224 bits (571), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 124/306 (40%), Positives = 172/306 (56%), Gaps = 8/306 (2%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDH----GDLAFVDVPND 61 K + I+ APFS GQP GVE GP L K GL + +++ ++ R G + +D Sbjct: 14 KKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASD 73 Query: 62 SPFQI--VKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLC 119 + +I VK PR + E++ V + G + +GGDHS+A+G+++G VHPD Sbjct: 74 NGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAG 133 Query: 120 VIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGL 179 VIWVDAH DINT T SGNLHG P++ LL + P+ FSWV + I YIGL Sbjct: 134 VIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPEC--FSWVPQVLKPNKIAYIGL 191 Query: 180 RDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPV 239 R VD E I+ L I FSM VD+ GI KV+ + + P+ +S+DVD +DP+ Sbjct: 192 RAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPL 251 Query: 240 FTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVAL 299 + PATGTPV GGLS+RE L++ E I + G L LD++E NP L T V T++ A+ Sbjct: 252 YVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISVGCAI 311 Query: 300 TLSCFG 305 G Sbjct: 312 ARCMMG 317 >6DKT-A nrPDB Length = 296 Score = 219 bits (559), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 128/304 (42%), Positives = 178/304 (58%), Gaps = 14/304 (4%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAF--VDVPNDSP 63 K I +IG P GQ R GV+ GP+A+R A L+E+L + Y V D GD+ + ND Sbjct: 3 KTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTVEDLGDIPINREKIKNDEE 62 Query: 64 FQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWV 123 KN SV NE+LA V + + +VLGGDHS+AIG+++G A+ + +L VIW Sbjct: 63 L---KNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIGTLAGTAKHYDNLGVIWY 119 Query: 124 DAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVD 183 DAH D+NT T+ SGN+HG P+A L ++ G++ P I +++V IG R +D Sbjct: 120 DAHGDLNTLETSPSGNIHGMPLAVSLGIGHESLVNLEGYA---PKIKPENVVIIGARSLD 176 Query: 184 PGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPA 243 GE IK G+K ++M E+D+LG+ KV+EET YL +HLS D+DGLDP P Sbjct: 177 EGERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYL--SACDGVHLSLDLDGLDPNDAPG 234 Query: 244 TGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSC 303 GTPVVGG+SYRE E +Y G+++ + +EVNP L + +T TAV L S Sbjct: 235 VGTPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPIL----DHKNKTGKTAVELVESL 290 Query: 304 FGTK 307 G K Sbjct: 291 LGKK 294 >6NBK-A nrPDB Length = 297 Score = 219 bits (559), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 124/302 (41%), Positives = 176/302 (58%), Gaps = 9/302 (2%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQ 65 K I +IG P GQ R GV+ GP+A+R AG++E+++E Y+V+D GD+ Sbjct: 3 KEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDENT 62 Query: 66 IVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDA 125 ++N V +LA+ V + G +VLGGDHS+AIG+++G A+ + +L VIW DA Sbjct: 63 KLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDA 122 Query: 126 HTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185 H D+NT T+ SGN+HG +A L D+ G P + +++V IG R +D G Sbjct: 123 HGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYG---AYPKVKKENVVIIGARALDEG 179 Query: 186 EHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATG 245 E I+ GIK FSM E+D++G+ VMEET +YL +HLS D+DGLDP P G Sbjct: 180 EKDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYL--SHTDGVHLSLDLDGLDPHDAPGVG 237 Query: 246 TPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFG 305 TPV+GGLSYRE E + + +++ + +EVN L +E RT TAVAL S FG Sbjct: 238 TPVIGGLSYRESHLAMEMLAEADIITSAEFVEVNTIL----DERNRTATTAVALMGSLFG 293 Query: 306 TK 307 K Sbjct: 294 EK 295 >2EF5-A nrPDB Length = 290 Score = 203 bits (517), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 119/305 (39%), Positives = 173/305 (56%), Gaps = 24/305 (7%) Query: 8 IEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIV 67 + ++G P G R GV+ GP+ALR A L+E+L++ Y V D GD VP Sbjct: 3 VAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGD-----VPVSLARASR 57 Query: 68 KNPRSVGKANEQLAAVVAETQK-----NGTISVVLGGDHSMAIGSISGHARVHPDLCVIW 122 + R + E AA + ++ G +VLGGDHS+++GS++G AR + V+W Sbjct: 58 RRGRGLAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGR-RVGVVW 116 Query: 123 VDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDV 182 VDAH D NTP T+ SGN+HG P+A L + +V F V P KD+V +G+R + Sbjct: 117 VDAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEV--FRAVDP----KDVVLVGVRSL 170 Query: 183 DPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTP 242 DPGE ++K G++ ++M EVD+LG+ ++ EE +L G P+H+S D D LDP P Sbjct: 171 DPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGL---PLHVSLDADVLDPTLAP 227 Query: 243 ATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLS 302 GTPV GGL+YRE + E + ++G + LD++EVNP L +E RT V L LS Sbjct: 228 GVGTPVPGGLTYREAHLLMEILAESGRVQSLDLVEVNPIL----DERNRTAEMLVGLALS 283 Query: 303 CFGTK 307 G + Sbjct: 284 LLGKR 288 >3SL1-A nrPDB Length = 413 Score = 139 bits (349), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 76/232 (32%), Positives = 125/232 (53%), Gaps = 5/232 (2%) Query: 60 NDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLC 119 N+ + ++N + +G ++ L ++ + + +GGDH +A SI +++ +L Sbjct: 154 NNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLR 213 Query: 120 VIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAK--DIVYI 177 VIW+DAH DIN P T+ SGN HG +A L K K VP F W K + I Sbjct: 214 VIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKK---VPYFEWSENLTYLKPENTAII 270 Query: 178 GLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLD 237 G+RD+D E I+K I Y+++ +++K GI + + PIH+S D+D +D Sbjct: 271 GIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVD 330 Query: 238 PVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEV 289 VF P TGT GGL+YRE + + + +T + +D++E NP+L + ++V Sbjct: 331 NVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKV 382 Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 26/48 (54%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDL 53 K + IIG+P + GQP GGV+ LRK GL + + D G++ Sbjct: 24 KNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNI 71 >4DZ4-A nrPDB Length = 324 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 85/295 (28%), Positives = 125/295 (42%), Gaps = 35/295 (11%) Query: 21 RGGVEKGPAALRKAGL-VEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQ 79 R G GP+A+R A + + +L + DLA +D D F +P S+ A + Sbjct: 63 RSGARLGPSAVRAASVQLAELNPYPWGFDPFDDLAVIDY-GDCWFD-AHHPLSIKPAIVE 120 Query: 80 LAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPD-LCVIWVDAHTDINTPLTTSSG 138 A + ++ + LGGDH + + HA+ + L +I DAH D S Sbjct: 121 HARTILQSDAR---MLTLGGDHYITYPLLIAHAQKYGKPLSLIHFDAHCDTWADDAPDSL 177 Query: 139 NLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYF 198 N HG K +K I K V +G+R + LGI Sbjct: 178 N-HGT---MFYKAVKDGL------------IDPKASVQVGIRTWND------DYLGINVL 215 Query: 199 SMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGL 258 V + G +E S + GR P +L+FD+D LDP F P TGTPV GGLS + L Sbjct: 216 DAAWVHEHGARATLERIESIVGGR---PAYLTFDIDCLDPAFAPGTGTPVAGGLSSAQAL 272 Query: 259 YITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHK 313 I + L+ G D++EV P ++ E+T VA L C +R+ + Sbjct: 273 AIVRGLGGVNLI-GADVVEVAPAYDQS--EITAIAAAHVACDLLCLWRQRKAGAR 324 >1GQ7-A nrPDB Length = 313 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 82/297 (27%), Positives = 134/297 (45%), Gaps = 52/297 (17%) Query: 1 MSSKPKP----IEIIGAPFSKGQP-RGGVEKGPAALR-KAGLVEKLKETE-------YNV 47 + P+P + +IGAP+ G R G GP A+R ++GL+ + N Sbjct: 21 LPHDPQPRGYDVVVIGAPYDGGTSYRPGARFGPQAIRSESGLIHGVGIDRGPGTFDLINC 80 Query: 48 RDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGS 107 D GD+ N +PF + ++ A L+ ++ K +++GGDHS+ + + Sbjct: 81 VDAGDI------NLTPFDMNI---AIDTAQSHLSGLL----KANAAFLMIGGDHSLTVAA 127 Query: 108 ISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTP 167 + A H L V+ +DAH+D N P HG P + E Sbjct: 128 LRAVAEQHGPLAVVHLDAHSDTN-PAFYGGRYHHGTPFRHGIDE---------------K 171 Query: 168 CISAKDIVYIGLRDVDPGEHYI--IKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRK-- 223 I +V IG+R +P + + G++ + E +LG+G + L+ K Sbjct: 172 LIDPAAMVQIGIRGHNPKPDSLDYARGHGVRVVTADEFGELGVGGTAD-----LIREKVG 226 Query: 224 KRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNP 280 +RP+++S D+D +DP F P TGTP GGL RE L + + + G D+MEV+P Sbjct: 227 QRPVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCVGDLKPV-GFDVMEVSP 282 >3NIP-A nrPDB Length = 326 Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 73/281 (25%), Positives = 121/281 (43%), Gaps = 38/281 (13%) Query: 8 IEIIGAPFSKGQP-RGGVEKGPAALRK-AGLVEKLKETE----YNVRDHGDLAFVDVPND 61 + +IG P+ G R G GP +R + L+ K+ Y++ GDL D Sbjct: 37 VGLIGVPWDGGTTNRAGARHGPREVRNLSSLMRKVHHVSRIAPYDLVRVGDL------GD 90 Query: 62 SPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVI 121 +P NP + + ++ + GT+ + +GGDH + + R P L ++ Sbjct: 91 APV----NPIDLLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGRERP-LGMV 145 Query: 122 WVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRD 181 DAH+D N + HG P ++E + P + V IG+R Sbjct: 146 HFDAHSDTNDRYFGDNPYTHGTPFRRAIEE-----------GLLDPLRT----VQIGIRG 190 Query: 182 --VDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPV 239 P + + GI+ M E +LG+ + E + P ++SFDVD LDP Sbjct: 191 SVYSPDDDAFARECGIRVIHMEEFVELGVEATLAEARRVV---GAGPTYVSFDVDVLDPA 247 Query: 240 FTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNP 280 F P TGTP +GG++ + + + L+ G D++EV+P Sbjct: 248 FAPGTGTPEIGGMTSLQAQQLVRGLRGLDLV-GADVVEVSP 287 >3PZL-A nrPDB Length = 313 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 80/311 (25%), Positives = 132/311 (42%), Gaps = 54/311 (17%) Query: 10 IIGAPFSKGQP-RGGVEKGPAALRKAGLVEKLKETEYNV----RDHGDLAFVDVPNDSPF 64 + G PF R G + P ++R A + + E Y + DL ++ D + Sbjct: 39 VFGIPFDNTSSYRRGSKYAPDSIRGAYVNLESYEYSYGIDLLASGMADLGDMEESEDVEY 98 Query: 65 QIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHP-DLCVIWV 123 I + + +VV+ +G I ++LGG+HS+ +G++ R P D+ ++ V Sbjct: 99 VI-----------DTVESVVSAVMSDGKIPIMLGGEHSITVGAV----RALPKDVDLVIV 143 Query: 124 DAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVD 183 DAH+D + GN + + + D+ G +T IG+R V Sbjct: 144 DAHSDFRSSYM---GNKYNHAC------VTRRALDLLGEGRITS---------IGIRSVS 185 Query: 184 PGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPA 243 E + + S +V K GI K +EE + RK R +++S D+DG+DP + PA Sbjct: 186 REEFEDPDFRKVSFISSFDVKKNGIDKYIEE-----VDRKSRRVYISVDMDGIDPAYAPA 240 Query: 244 TGTPVVGGLSYREGLYITEEI-YKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLS 302 GTP GL+ + + E + YK G DI+E +P + A L Sbjct: 241 VGTPEPFGLADTDVRRLIERLSYKA---VGFDIVEFSPLYDNG------NTSMLAAKLLQ 291 Query: 303 CFGTKREGNHK 313 F RE +K Sbjct: 292 VFIASREKYYK 302 >4G3H-A nrPDB Length = 330 Score = 73.9 bits (180), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 55/225 (24%), Positives = 103/225 (45%), Gaps = 20/225 (8%) Query: 76 ANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPD--LCVIWVDAHTDINTPL 133 E L + E + ++L +H+ G VH D + ++++DAH DI+T Sbjct: 66 CKENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAY 125 Query: 134 TTSSGNLHGQPVAFLLKELKGKF---PDVPGFSWVTPC----------ISAKDIVYIGLR 180 + S ++HG P+ +L ++ F + +W C I K +VY G+R Sbjct: 126 DSDSKHIHGMPLGMVLNRVRSGFNRMSESEEKAWQKLCSLGLEKGGLEIDPKCLVYFGVR 185 Query: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 + E +I+ L I FS+ + + + +V+++T L + I+LS D+D +D Sbjct: 186 STEQSERDVIRELQIPLFSVDAI-RENMQEVVQKTKESL--KAVDIIYLSLDLDIMDGKL 242 Query: 241 TPATGTPVVGGLSYREGLYITEEIYKT--GLLSGLDIMEVNPTLG 283 +TG GLS+ E + + ++ L +++ E NPT+ Sbjct: 243 FTSTGVRENNGLSFDELKQLLGLLLESFKDRLKAVEVTEYNPTVS 287 >3NIO-A nrPDB Length = 319 Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 66/282 (23%), Positives = 120/282 (42%), Gaps = 44/282 (15%) Query: 10 IIGAPFSKGQP-RGGVEKGPAALRKAGLVEKLKET--------EYNVRDHGDLAFVDVPN 60 +G P G R G GP +R ++ + NV D GD+A Sbjct: 42 FVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIGDVAI----- 96 Query: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCV 120 + F +++ R + + +++ +G + + LGGDH++ + + + H + + Sbjct: 97 -NTFNLLEAVRIIEQEYDRILG-------HGILPLTLGGDHTITLPILRAIKKKHGKVGL 148 Query: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 + VDAH D+N ++ G+ +A + D+ + +V IGLR Sbjct: 149 VHVDAHADVND-------HMFGEKIAHGTTFRRAVEEDL---------LDCDRVVQIGLR 192 Query: 181 --DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDP 238 + + G + E + +M E + G P++LSFD+DG+DP Sbjct: 193 AQGYTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGG---PVYLSFDIDGIDP 249 Query: 239 VFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNP 280 + P TGTP +GGL+ + + I L+ G D++EV+P Sbjct: 250 AWAPGTGTPEIGGLTTIQAMEIIRGCQGLDLI-GCDLVEVSP 290 >4RHL-A nrPDB Length = 351 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/220 (28%), Positives = 95/220 (43%), Gaps = 44/220 (20%) Query: 86 ETQKNGTISVVLGGDHSMAIGSISGHARVHP--DLCVIWVDAHTDINTPLTTSSGNLHGQ 143 E + G + V +GGD S + + + R+ P D+ ++ DAH ++ P + Sbjct: 129 ELLEKGYVPVSVGGDGSATLSMVEAYKRLFPSDDIVIVHFDAHPSVSDPRS--------- 179 Query: 144 PVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEV 203 P+ LL KG K +V +G R V + + K + Y M + Sbjct: 180 PLRVLLD--KGLL---------------KGVVSVGNRQVSSEDRKVRKLHKMFYMDMHAI 222 Query: 204 DKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEE 263 G+ F R P+ +S D D LDP F PA +PV GGLS R+ L+I Sbjct: 223 YSKGL-------FCIRDIRNDYPVFISIDADVLDPAFAPAVDSPVAGGLSTRDLLHIMNG 275 Query: 264 IYKTGLLSGLDIMEVNPTLGKTPEEVTRTVN---TAVALT 300 I ++ G+D+ NP L +V R N TA+AL+ Sbjct: 276 IRGPKVV-GIDVYGYNPDL-----DVYRKDNVGLTAIALS 309 >1WOG-A nrPDB Length = 305 Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 78/293 (26%), Positives = 120/293 (40%), Gaps = 56/293 (19%) Query: 8 IEIIGAPFSKGQP-RGGVEKGPAALRKA---------GLVEKLKETEYNVRDHGDLAFVD 57 + +G PF R G P ALR+A GL K + D GD V Sbjct: 31 VAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGD---VI 87 Query: 58 VPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPD 117 +P+ P Q+ A++++ + + + V LGGDHS++ + A V PD Sbjct: 88 LPSLEP-QL---------AHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFADV-PD 136 Query: 118 LCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYI 177 L V+ +DAH D T + N K+ + F C + ++V+I Sbjct: 137 LHVVQLDAHLDF-----TDTRN-------------DTKWSNSSPFRRA--CEALPNLVHI 176 Query: 178 ---GLRDV--DPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFD 232 GLR + DP + G M +V G + + L R + ++ S D Sbjct: 177 TTVGLRGLRFDPEAVAAARARGHTIIPMDDVTADLAGVLAQ------LPRGQN-VYFSVD 229 Query: 233 VDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKT 285 VDG DP P T +P GL+Y +G+ I + GLD++E+ P L T Sbjct: 230 VDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPT 282 >3LHL-A nrPDB Length = 287 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 62/246 (25%), Positives = 98/246 (39%), Gaps = 47/246 (19%) Query: 44 EYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQK---NGTISVVLGGD 100 +YN+ D+GDL SVG + L + ET K + + ++GG+ Sbjct: 54 DYNICDYGDLEI----------------SVGSTEQVLKEIYQETYKIVRDSKVPFMIGGE 97 Query: 101 HSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVP 160 H + + + + D+ VI DAHTD+ S N H + + D+ Sbjct: 98 HLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSK-NSHATVIK--------RIWDIV 148 Query: 161 GFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLL 220 G I G+R E Y + +D E + L Sbjct: 149 G---------DNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGID------TFENIVNMLN 193 Query: 221 GRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGL-LSGLDIMEVN 279 G+ I+L+ D+D LD P TGTP GG++YRE I + I + + + G DI+E++ Sbjct: 194 GKN---IYLTIDLDVLDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELS 250 Query: 280 PTLGKT 285 P T Sbjct: 251 PDYDTT 256 >3M1R-A nrPDB Length = 322 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 51/194 (26%), Positives = 88/194 (45%), Gaps = 24/194 (12%) Query: 93 ISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKEL 152 + ++LGGD+S++ +I A+ VI DAH D+ T G +G P LL E Sbjct: 122 VPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRN--TEDGGPTNGTPFRRLLDE- 178 Query: 153 KGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHY--IIKTLGIKYFSMTEVDKLGIGK 210 I + ++ +G+R+ + Y K + +M + + G+ Sbjct: 179 --------------EIIEGQHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIP 224 Query: 211 VMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVG--GLSYREGLYITEEIYKTG 268 ++E ++ K I +S D+D LD P G P +G GL E L + I + Sbjct: 225 TIKEILP-VVQDKTDFIFISVDMDVLDQSHAP--GCPAIGPGGLYTDELLEAVKYIAQQP 281 Query: 269 LLSGLDIMEVNPTL 282 ++G++I+EV+PTL Sbjct: 282 NVAGIEIVEVDPTL 295 >1XFK-A nrPDB Length = 336 Score = 35.8 bits (81), Expect = 0.027, Method: Compositional matrix adjust. Identities = 56/239 (23%), Positives = 88/239 (36%), Gaps = 66/239 (27%) Query: 75 KANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHAR-------VHPDLCVIWVDAHT 127 +A ++ A V+ + + ++VLGG H +A + G A+ P + +I DAH Sbjct: 102 QAQQECAQVIQQALPHAR-AIVLGGGHEIAWATFQGLAQHFLATGVKQPRIGIINFDAHF 160 Query: 128 DINT------PLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRD 181 D+ T P+ SSG Q F ++ G+ + C Sbjct: 161 DLRTFESELAPVRPSSGTPFNQIHHFCQQQ---------GWDFHYAC------------- 198 Query: 182 VDPGEHYIIKTLGIKYFSMT-----EVDKLGIGKVMEETFSYL-----LGRKKRPI---- 227 LG+ S T DKLG+ V ++ FS L L + + I Sbjct: 199 -----------LGVSRASNTPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFIDDCD 247 Query: 228 --HLSFDVDGLDPVFTPATGTPVVGGLSYREGL--YITEEIYKTGLLSGLDIMEVNPTL 282 +L+ D+D P P G+S E L Y ++ L DI E NP+ Sbjct: 248 YLYLTIDLDVFPAASAPGVSAPAARGVSL-EALAPYFDRILHYKNKLMIADIAEYNPSF 305 >4V4O-A nrPDB Length = 543 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 21/61 (34%), Positives = 31/61 (50%) Query: 146 AFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDK 205 A LLKE+ K DV G T + A+ IV GL++V G + + GI+ V+K Sbjct: 70 AQLLKEVASKTNDVAGDGTTTATVLAQAIVREGLKNVAAGANPLALKRGIEKAVEAAVEK 129 Query: 206 L 206 + Sbjct: 130 I 130 >1MQS-A nrPDB Length = 671 Score = 31.2 bits (69), Expect = 0.68, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 6/76 (7%) Query: 120 VIWVDAHTDINTPLTTSS----GNL--HGQPVAFLLKELKGKFPDVPGFSWVTPCISAKD 173 +IW DI + T SS +L G V L+K+ + PDVP +V+P D Sbjct: 56 IIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENID 115 Query: 174 IVYIGLRDVDPGEHYI 189 I+ L+ E YI Sbjct: 116 IIVNDLKSDKYSEFYI 131 >4R3U-A nrPDB Length = 584 Score = 30.8 bits (68), Expect = 0.85, Method: Compositional matrix adjust. Identities = 44/201 (21%), Positives = 82/201 (40%), Gaps = 27/201 (13%) Query: 120 VIWVDAHTDINTPLTTSSGNLHGQPVAFLLK---ELKGKFPDVPGFSWVTPCISAKDIVY 176 + W++ I + L + + V LK E K +F + F V +A DI Sbjct: 12 MTWLEPQ--IKSQLQSERKDWEANEVGAFLKKAPERKEQFHTIGDFP-VQRTYTAADIAD 68 Query: 177 IGLRDVD-PGEHYIIK-----TLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLS 230 L D+ PG + + + ++M ++ G G+ + F YL+ + + I Sbjct: 69 TPLEDIGLPGRYPFTRGPYPTMYRSRTWTMRQIAGFGTGEDTNKRFKYLIAQGQTGISTD 128 Query: 231 FDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVT 290 FD+ L + P+ G REG+ I LL+ +D+ +++ V+ Sbjct: 129 FDMPTL---MGYDSDHPMSDGEVGREGVAIDTLADMEALLADIDLEKIS---------VS 176 Query: 291 RTVNTAVALTLSCF---GTKR 308 T+N + + L+ + G KR Sbjct: 177 FTINPSAWILLAMYVALGEKR 197 >1PZY-B nrPDB Length = 286 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/68 (22%), Positives = 30/68 (44%) Query: 29 AALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQ 88 A L G E LK+ +YN D+ + + + + ++ PR + A ++ + Q Sbjct: 113 AKLLNVGFKEALKDYDYNCFVFSDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQ 172 Query: 89 KNGTISVV 96 G +S + Sbjct: 173 YFGGVSAL 180 >1SJP-A nrPDB Length = 504 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 13/75 (17%) Query: 146 AFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDK 205 A L+KE+ K DV G T + A+ +V GLR+V G + LG+K Sbjct: 28 AELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGAN----PLGLKR-------- 75 Query: 206 LGIGKVMEETFSYLL 220 GI K +E+ LL Sbjct: 76 -GIEKAVEKVTETLL 89 >3EWD-A nrPDB Length = 370 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 254 YREGLYITEEIYKTGLLS---GLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKRE- 309 Y+EG+ + E Y ++ LDI ++ + K +EV ++ + + L C GT E Sbjct: 117 YKEGVVLMEFRYSPTFVAFKYNLDIELIHQAIVKGIKEVVELLDHKIHVALMCIGTGHEA 176 Query: 310 GNHKPETDY 318 N K D+ Sbjct: 177 ANIKASADF 185 >4QKO-B nrPDB Length = 134 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 6/91 (6%) Query: 7 PIEIIGAPFSKGQP-----RGGVEKGPAALRKAGLVEKLK-ETEYNVRDHGDLAFVDVPN 60 P ++ GA KGQP G +G A + + +KL+ +T N RD + ++ V N Sbjct: 3 PRDVPGAATGKGQPVSGNWLGAASQGEGAPIPSQIADKLRGKTFKNWRDFREQFWIAVAN 62 Query: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNG 91 D NP S+ + A V E+++ G Sbjct: 63 DPELSKQFNPGSLAVMRDGGAPYVRESEQAG 93 >2VWH-A nrPDB Length = 357 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 8/70 (11%) Query: 181 DVDPGEHYIIK--TLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDP 238 D DP +++ +LG+ +M +VD G + Y LGR+ RP ++ LD Sbjct: 170 DWDPSSAFVLGNGSLGLLTLAMLKVDDKGYENL------YCLGRRDRPDPTIDIIEELDA 223 Query: 239 VFTPATGTPV 248 + + TPV Sbjct: 224 TYVDSRQTPV 233 >3S2F-A nrPDB Length = 340 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 154 GKFPDVPGFSWVTPCISAKDIVYIGLR--DVDPGEHYIIKTLG 194 G PD GF + P + A VY GL+ D PG+ +I +G Sbjct: 134 GLLPDKVGFVEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIG 176 >4GYG-A nrPDB Length = 397 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 17/24 (70%) Query: 23 GVEKGPAALRKAGLVEKLKETEYN 46 GV K A L KAGL+ ++KE +Y+ Sbjct: 50 GVHKSIATLAKAGLIARMKEAKYD 73 >1AC5-A nrPDB Length = 483 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 3/66 (4%) Query: 4 KPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSP 63 +P I + G P VE GP + G KL E + GDL F+D P + Sbjct: 67 RPLIIWLNGGPGCSSMDGALVESGPFRVNSDG---KLYLNEGSWISKGDLLFIDQPTGTG 123 Query: 64 FQIVKN 69 F + +N Sbjct: 124 FSVEQN 129 >1WOU-A nrPDB Length = 123 Score = 27.7 bits (60), Expect = 7.0, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 20/39 (51%) Query: 158 DVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIK 196 D G SW C+ A+ +V GL+ + G +I +G K Sbjct: 36 DAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEK 74 >3HP7-A nrPDB Length = 291 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 20/28 (71%) Query: 252 LSYREGLYITEEIYKTGLLSGLDIMEVN 279 L+Y++GL+ T E K G+++GL + +N Sbjct: 12 LAYKQGLFETREQAKRGVMAGLVVNVIN 39 >4Z25-A nrPDB Length = 652 Score = 27.3 bits (59), Expect = 8.3, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 20/85 (23%) Query: 142 GQPVAFLLKELKGKFPDVPGFSWVTP--------------CISAKDIVYIGLRDVDPGEH 187 G+PV FLL + G P+V TP + A Y+G+ + G + Sbjct: 171 GEPVDFLLNKATGNVPNVEK---TTPDAVPLNLNDYEGVNSVVAFSSFYMGVNQLSDG-N 226 Query: 188 YIIKTLGIKYFSMTEVDK--LGIGK 210 YI K G Y + VD+ GIGK Sbjct: 227 YIRKYAGNTYLNRNYVDENGRGIGK 251 >2WZP-P nrPDB Length = 326 Score = 27.3 bits (59), Expect = 8.5, Method: Compositional matrix adjust. Identities = 11/36 (30%), Positives = 20/36 (55%) Query: 184 PGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYL 219 PG + IK Y+ +++D+L + EE FS++ Sbjct: 193 PGNYKYIKGTSYTYYGESDIDRLSRWDIKEEIFSFM 228 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5RLA-A nrPDB 458 e-129 3LP4-A nrPDB 443 e-125 1PQ3-A nrPDB 384 e-107 1CEV-A nrPDB 356 1e-98 6NBK-A nrPDB 351 2e-97 5YNL-A nrPDB 340 4e-94 6DKT-A nrPDB 340 7e-94 4ITY-A nrPDB 337 3e-93 4Q3T-A nrPDB 332 1e-91 2EF5-A nrPDB 296 8e-81 3SL1-A nrPDB 255 2e-68 4DZ4-A nrPDB 237 6e-63 3NIP-A nrPDB 235 2e-62 3NIO-A nrPDB 233 8e-62 1GQ7-A nrPDB 221 3e-58 3PZL-A nrPDB 219 1e-57 3LHL-A nrPDB 208 3e-54 4G3H-A nrPDB 198 2e-51 1WOG-A nrPDB 186 2e-47 3M1R-A nrPDB 185 2e-47 4RHL-A nrPDB 157 7e-39 Sequences not found previously or not previously below threshold: 1XFK-A nrPDB 95 5e-20 1GKH-A nrPDB 31 0.58 1QI9-A nrPDB 31 1.1 5HP5-A nrPDB 30 1.6 3EXA-A nrPDB 30 1.7 1JF0-A nrPDB 29 2.1 5ED4-A nrPDB 29 2.7 1KA9-F nrPDB 29 3.6 4FN5-A nrPDB 28 4.8 >5RLA-A nrPDB Length = 323 Score = 458 bits (1177), Expect = e-129, Method: Composition-based stats. Identities = 322/323 (99%), Positives = 323/323 (100%) Query: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN Sbjct: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 Query: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCV 120 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGD+SMAIGSISGHARVHPDLCV Sbjct: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDNSMAIGSISGHARVHPDLCV 120 Query: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF Sbjct: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 Query: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT Sbjct: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 Query: 301 LSCFGTKREGNHKPETDYLKPPK 323 LSCFGTKREGNHKPETDYLKPPK Sbjct: 301 LSCFGTKREGNHKPETDYLKPPK 323 >3LP4-A nrPDB Length = 322 Score = 443 bits (1138), Expect = e-125, Method: Composition-based stats. Identities = 281/323 (86%), Positives = 301/323 (93%), Gaps = 1/323 (0%) Query: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 MS+K + I IIGAPFSKGQPRGGVE+GP LRKAGL+EKLKE E +V+D+GDL F D+PN Sbjct: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 Query: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCV 120 DSPFQIVKNPRSVGKA+EQLA VAE +KNG IS+VLGGDHS+AIGSISGHARVHPDL V Sbjct: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 Query: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTT+SGNLHGQPV+FLLKELKGK PDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 DVDPGEHYI+KTLGIKYFSMTEVD+LGIGKVMEET SYLLGRKKRPIHLSFDVDGLDP F Sbjct: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 Query: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 TPATGTPVVGGL+YREGLYITEEIYKTGLLSGLDIMEVNP+LGKTPEEVTRTVNTAVA+T Sbjct: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 Query: 301 LSCFGTKREGNHKPETDYLKPPK 323 L+CFG REGNHKP DYL PPK Sbjct: 301 LACFGLAREGNHKP-IDYLNPPK 322 >1PQ3-A nrPDB Length = 306 Score = 384 bits (986), Expect = e-107, Method: Composition-based stats. Identities = 189/304 (62%), Positives = 235/304 (77%), Gaps = 1/304 (0%) Query: 8 IEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQ-I 66 + +IGAPFS+GQ R GVE GPAA+R+AGL+++L +++D GDL+F VP D + + Sbjct: 3 VAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNL 62 Query: 67 VKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAH 126 + NPRSVG AN++LA VV+ +G V LGGDHS+AIG+ISGHAR PDLCV+WVDAH Sbjct: 63 IVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAH 122 Query: 127 TDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGE 186 DINTPLTTSSGNLHGQPV+FLL+EL+ K P +PGFSW+ PCIS+ IVYIGLRDVDP E Sbjct: 123 ADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPPE 182 Query: 187 HYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGT 246 H+I+K I+YFSM ++D+LGI KVME TF L+G+++RPIHLSFD+D DP PATGT Sbjct: 183 HFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGT 242 Query: 247 PVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGT 306 PVVGGL+YREG+YI EEI+ TGLLS LD++EVNP L + EE T N AV + S FG Sbjct: 243 PVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQ 302 Query: 307 KREG 310 REG Sbjct: 303 TREG 306 >1CEV-A nrPDB Length = 299 Score = 356 bits (912), Expect = 1e-98, Method: Composition-based stats. Identities = 130/304 (42%), Positives = 188/304 (61%), Gaps = 10/304 (3%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAF--VDVPNDSP 63 KPI IIG P GQ R GV+ GP+A+R AG++E+L+ Y++ D GD+ + ++ Sbjct: 2 KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQG 61 Query: 64 FQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWV 123 ++N ++V +ANE+LAA V + + G +VLGGDHS+AIG+++G A+ + L VIW Sbjct: 62 DSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWY 121 Query: 124 DAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVD 183 DAH D+NT T+ SGN+HG P+A L + G+S P I + +V IG+R +D Sbjct: 122 DAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYS---PKIKPEHVVLIGVRSLD 178 Query: 184 PGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPA 243 GE I+ GIK ++M EVD+LG+ +VMEET +YL R +HLS D+DGLDP P Sbjct: 179 EGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKER-TDGVHLSLDLDGLDPSDAPG 237 Query: 244 TGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSC 303 GTPV+GGL+YRE E + + +++ + +EVNP L E +T + AVAL S Sbjct: 238 VGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILD----ERNKTASVAVALMGSL 293 Query: 304 FGTK 307 FG K Sbjct: 294 FGEK 297 >6NBK-A nrPDB Length = 297 Score = 351 bits (900), Expect = 2e-97, Method: Composition-based stats. Identities = 124/302 (41%), Positives = 175/302 (57%), Gaps = 9/302 (2%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQ 65 K I +IG P GQ R GV+ GP+A+R AG++E+++E Y+V+D GD+ Sbjct: 3 KEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDENT 62 Query: 66 IVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDA 125 ++N V +LA+ V + G +VLGGDHS+AIG+++G A+ + +L VIW DA Sbjct: 63 KLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDA 122 Query: 126 HTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185 H D+NT T+ SGN+HG +A L D+ G P + +++V IG R +D G Sbjct: 123 HGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYG---AYPKVKKENVVIIGARALDEG 179 Query: 186 EHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATG 245 E I+ GIK FSM E+D++G+ VMEET +YL +HLS D+DGLDP P G Sbjct: 180 EKDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYL--SHTDGVHLSLDLDGLDPHDAPGVG 237 Query: 246 TPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFG 305 TPV+GGLSYRE E + + +++ + +EVN L E RT TAVAL S FG Sbjct: 238 TPVIGGLSYRESHLAMEMLAEADIITSAEFVEVNTILD----ERNRTATTAVALMGSLFG 293 Query: 306 TK 307 K Sbjct: 294 EK 295 >5YNL-A nrPDB Length = 362 Score = 340 bits (872), Expect = 4e-94, Method: Composition-based stats. Identities = 143/309 (46%), Positives = 191/309 (61%), Gaps = 5/309 (1%) Query: 3 SKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHG-DLAFVDVPND 61 + P+ I+G PFS GQP+ GV GP L ++GL+ ++ + V G D V + +D Sbjct: 53 ATPRTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSD 112 Query: 62 SPF---QIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDL 118 +P +K PR V + + +A V G ++V LGGDHS+A+G++SG + +P+ Sbjct: 113 TPDPDIGRLKQPRLVSRVTKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKAYPEA 172 Query: 119 CVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIG 178 C+IWVDAH DINTP TT SG LHG PV+FLL ++P FSW+ PC+ + IVYIG Sbjct: 173 CLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGTSSEEIPEFSWIKPCLKPERIVYIG 232 Query: 179 LRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDP 238 LRD+D GE I+K IK FSM VDK GIGKV+E ++ + RPIHLSFDVD LDP Sbjct: 233 LRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVNPDRTRPIHLSFDVDALDP 292 Query: 239 VFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVA 298 P+TGT V GGL++REG YI E I +T LL LDIME+NP+LG V +TV+ + Sbjct: 293 SVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGAL-ASVAQTVDVGRS 351 Query: 299 LTLSCFGTK 307 L G Sbjct: 352 LVRCALGET 360 >6DKT-A nrPDB Length = 296 Score = 340 bits (871), Expect = 7e-94, Method: Composition-based stats. Identities = 126/302 (41%), Positives = 177/302 (58%), Gaps = 10/302 (3%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQ 65 K I +IG P GQ R GV+ GP+A+R A L+E+L + Y V D GD+ + + Sbjct: 3 KTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTVEDLGDIPINREKIKN-DE 61 Query: 66 IVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDA 125 +KN SV NE+LA V + + +VLGGDHS+AIG+++G A+ + +L VIW DA Sbjct: 62 ELKNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIGTLAGTAKHYDNLGVIWYDA 121 Query: 126 HTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185 H D+NT T+ SGN+HG P+A L ++ G++ P I +++V IG R +D G Sbjct: 122 HGDLNTLETSPSGNIHGMPLAVSLGIGHESLVNLEGYA---PKIKPENVVIIGARSLDEG 178 Query: 186 EHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATG 245 E IK G+K ++M E+D+LG+ KV+EET YL +HLS D+DGLDP P G Sbjct: 179 ERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYL--SACDGVHLSLDLDGLDPNDAPGVG 236 Query: 246 TPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFG 305 TPVVGG+SYRE E +Y G+++ + +EVNP L +T TAV L S G Sbjct: 237 TPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPILD----HKNKTGKTAVELVESLLG 292 Query: 306 TK 307 K Sbjct: 293 KK 294 >4ITY-A nrPDB Length = 330 Score = 337 bits (865), Expect = 3e-93, Method: Composition-based stats. Identities = 124/308 (40%), Positives = 172/308 (55%), Gaps = 8/308 (2%) Query: 6 KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDH----GDLAFVDVPND 61 K + I+ APFS GQP GVE GP L K GL + +++ ++ R G + +D Sbjct: 14 KKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASD 73 Query: 62 SPFQI--VKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLC 119 + +I VK PR + E++ V + G + +GGDHS+A+G+++G VHPD Sbjct: 74 NGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAG 133 Query: 120 VIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGL 179 VIWVDAH DINT T SGNLHG P++ LL + P+ FSWV + I YIGL Sbjct: 134 VIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPEC--FSWVPQVLKPNKIAYIGL 191 Query: 180 RDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPV 239 R VD E I+ L I FSM VD+ GI KV+ + + P+ +S+DVD +DP+ Sbjct: 192 RAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPL 251 Query: 240 FTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVAL 299 + PATGTPV GGLS+RE L++ E I + G L LD++E NP L T V T++ A+ Sbjct: 252 YVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISVGCAI 311 Query: 300 TLSCFGTK 307 G Sbjct: 312 ARCMMGET 319 >4Q3T-A nrPDB Length = 385 Score = 332 bits (851), Expect = 1e-91, Method: Composition-based stats. Identities = 136/326 (41%), Positives = 202/326 (61%), Gaps = 19/326 (5%) Query: 4 KPKPI----EIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVP 59 KPK + +G P ++GQP+ G +GP +RK+ + + E + D GD+ V++ Sbjct: 37 KPKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELN 96 Query: 60 N-DSPFQI-VKNPRSVGKANEQLAAVVAETQK------------NGTISVVLGGDHSMAI 105 + P + +K RS ++A V E K T V++GGDHSMA Sbjct: 97 EAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSKSTPLVIVGGDHSMAT 156 Query: 106 GSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWV 165 G+I GHA PDLCV+W+DAH DINTPL ++SGN+HG P++FL+KEL+ + P + F + Sbjct: 157 GTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGI 216 Query: 166 TPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKR 225 PC++A +I YIGLRD+D E + I+ GI YF+M +VD++GI V++E + R ++ Sbjct: 217 KPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEK 276 Query: 226 PIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKT 285 IHLSFD+D LDP+ P+TGT V GGL+ REGL I EE+ TG LS +++ E+NP LG + Sbjct: 277 AIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLG-S 335 Query: 286 PEEVTRTVNTAVALTLSCFGTKREGN 311 E+V +T ++AV + +C G R G+ Sbjct: 336 QEDVLKTQSSAVHILRACLGHCRSGH 361 >2EF5-A nrPDB Length = 290 Score = 296 bits (758), Expect = 8e-81, Method: Composition-based stats. Identities = 111/300 (37%), Positives = 163/300 (54%), Gaps = 14/300 (4%) Query: 8 IEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIV 67 + ++G P G R GV+ GP+ALR A L+E+L++ Y V D GD+ Sbjct: 3 VAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRG 62 Query: 68 KNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHT 127 +A + G +VLGGDHS+++GS++G AR + V+WVDAH Sbjct: 63 LAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGR-RVGVVWVDAHA 121 Query: 128 DINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEH 187 D NTP T+ SGN+HG P+A L + +V + KD+V +G+R +DPGE Sbjct: 122 DFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVF------RAVDPKDVVLVGVRSLDPGEK 175 Query: 188 YIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTP 247 ++K G++ ++M EVD+LG+ ++ EE +L G P+H+S D D LDP P GTP Sbjct: 176 RLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGL---PLHVSLDADVLDPTLAPGVGTP 232 Query: 248 VVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTK 307 V GGL+YRE + E + ++G + LD++EVNP L E RT V L LS G + Sbjct: 233 VPGGLTYREAHLLMEILAESGRVQSLDLVEVNPILD----ERNRTAEMLVGLALSLLGKR 288 >3SL1-A nrPDB Length = 413 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 79/262 (30%), Positives = 132/262 (50%), Gaps = 16/262 (6%) Query: 57 DVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHP 116 N+ + ++N + +G ++ L ++ + + +GGDH +A SI +++ Sbjct: 151 KYKNNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQ 210 Query: 117 DLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPC--ISAKDI 174 +L VIW+DAH DIN P T+ SGN HG +A L K K VP F W + ++ Sbjct: 211 NLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKK---VPYFEWSENLTYLKPENT 267 Query: 175 VYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVD 234 IG+RD+D E I+K I Y+++ +++K GI + + PIH+S D+D Sbjct: 268 AIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDID 327 Query: 235 GLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEV----- 289 +D VF P TGT GGL+YRE + + + +T + +D++E NP+L + ++V Sbjct: 328 SVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSL 387 Query: 290 ------TRTVNTAVALTLSCFG 305 T+T + L G Sbjct: 388 PILDNATKTGKLCLELIARVLG 409 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 26/49 (53%) Query: 5 PKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDL 53 K + IIG+P + GQP GGV+ LRK GL + + D G++ Sbjct: 23 SKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNI 71 >4DZ4-A nrPDB Length = 324 Score = 237 bits (604), Expect = 6e-63, Method: Composition-based stats. Identities = 86/303 (28%), Positives = 126/303 (41%), Gaps = 36/303 (11%) Query: 14 PFSKGQP-RGGVEKGPAALRKAGL-VEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPR 71 P R G GP+A+R A + + +L + DLA +D D F +P Sbjct: 55 PLDLATTFRSGARLGPSAVRAASVQLAELNPYPWGFDPFDDLAVIDY-GDCWFD-AHHPL 112 Query: 72 SVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPD-LCVIWVDAHTDIN 130 S+ A + A + ++ + LGGDH + + HA+ + L +I DAH D Sbjct: 113 SIKPAIVEHARTILQSDAR---MLTLGGDHYITYPLLIAHAQKYGKPLSLIHFDAHCDTW 169 Query: 131 TPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYII 190 S N HG K +K I K V +G+R + Sbjct: 170 ADDAPDSLN-HGT---MFYKAVKDGL------------IDPKASVQVGIRTWND------ 207 Query: 191 KTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVG 250 LGI V + G +E S + GR P +L+FD+D LDP F P TGTPV G Sbjct: 208 DYLGINVLDAAWVHEHGARATLERIESIVGGR---PAYLTFDIDCLDPAFAPGTGTPVAG 264 Query: 251 GLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREG 310 GLS + L I + L+ G D++EV P ++ E+T VA L C +R+ Sbjct: 265 GLSSAQALAIVRGLGGVNLI-GADVVEVAPAYDQS--EITAIAAAHVACDLLCLWRQRKA 321 Query: 311 NHK 313 + Sbjct: 322 GAR 324 >3NIP-A nrPDB Length = 326 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 73/308 (23%), Positives = 119/308 (38%), Gaps = 39/308 (12%) Query: 8 IEIIGAPFSKGQP-RGGVEKGPAALRK-AGLVEKLKETE----YNVRDHGDLAFVDVPND 61 + +IG P+ G R G GP +R + L+ K+ Y++ GDL V Sbjct: 37 VGLIGVPWDGGTTNRAGARHGPREVRNLSSLMRKVHHVSRIAPYDLVRVGDLGDAPV--- 93 Query: 62 SPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVI 121 NP + + ++ + GT+ + +GGDH + + R P L ++ Sbjct: 94 -------NPIDLLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGRERP-LGMV 145 Query: 122 WVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRD 181 DAH+D N + HG P ++E + V IG+R Sbjct: 146 HFDAHSDTNDRYFGDNPYTHGTPFRRAIEEG---------------LLDPLRTVQIGIRG 190 Query: 182 --VDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPV 239 P + + GI+ M E +LG+ + E + P ++SFDVD LDP Sbjct: 191 SVYSPDDDAFARECGIRVIHMEEFVELGVEATLAEARRVV---GAGPTYVSFDVDVLDPA 247 Query: 240 FTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVAL 299 F P TGTP +GG++ + + + L+ G D++EV+P L Sbjct: 248 FAPGTGTPEIGGMTSLQAQQLVRGLRGLDLV-GADVVEVSPPFDVGGATALVGATMMFEL 306 Query: 300 TLSCFGTK 307 L Sbjct: 307 -LCLLAES 313 >3NIO-A nrPDB Length = 319 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 70/312 (22%), Positives = 125/312 (40%), Gaps = 44/312 (14%) Query: 9 EIIGAPFSKGQP-RGGVEKGPAALRKAGLVEKLKET--------EYNVRDHGDLAFVDVP 59 +G P G R G GP +R ++ + NV D GD+A Sbjct: 41 AFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIGDVAI---- 96 Query: 60 NDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLC 119 + F +++ R + + +++ +G + + LGGDH++ + + + H + Sbjct: 97 --NTFNLLEAVRIIEQEYDRILG-------HGILPLTLGGDHTITLPILRAIKKKHGKVG 147 Query: 120 VIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGL 179 ++ VDAH D+N ++ G+ +A + D+ + +V IGL Sbjct: 148 LVHVDAHADVND-------HMFGEKIAHGTTFRRAVEEDL---------LDCDRVVQIGL 191 Query: 180 R--DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLD 237 R + + G + E + +M E + G P++LSFD+DG+D Sbjct: 192 RAQGYTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGG---GPVYLSFDIDGID 248 Query: 238 PVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAV 297 P + P TGTP +GGL+ + + I L+ G D++EV+P T N Sbjct: 249 PAWAPGTGTPEIGGLTTIQAMEIIRGCQGLDLI-GCDLVEVSPPYDTTGNTSLLGANLLY 307 Query: 298 ALTLSCFGTKRE 309 + G R Sbjct: 308 EMLCVLPGVVRR 319 >1GQ7-A nrPDB Length = 313 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 81/315 (25%), Positives = 130/315 (41%), Gaps = 48/315 (15%) Query: 1 MSSKPKP----IEIIGAPFSKGQP-RGGVEKGPAALR-KAGLVEKLKETE-------YNV 47 + P+P + +IGAP+ G R G GP A+R ++GL+ + N Sbjct: 21 LPHDPQPRGYDVVVIGAPYDGGTSYRPGARFGPQAIRSESGLIHGVGIDRGPGTFDLINC 80 Query: 48 RDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGS 107 D GD+ N +PF + ++ A L+ K +++GGDHS+ + + Sbjct: 81 VDAGDI------NLTPFDMN---IAIDTAQSHLSG----LLKANAAFLMIGGDHSLTVAA 127 Query: 108 ISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTP 167 + A H L V+ +DAH+D N P HG P + E Sbjct: 128 LRAVAEQHGPLAVVHLDAHSDTN-PAFYGGRYHHGTPFRHGIDE---------------K 171 Query: 168 CISAKDIVYIGLRDVDPGEH--YIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKR 225 I +V IG+R +P + G++ + E +LG+G + + +R Sbjct: 172 LIDPAAMVQIGIRGHNPKPDSLDYARGHGVRVVTADEFGELGVGGTADLIREKV---GQR 228 Query: 226 PIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKT 285 P+++S D+D +DP F P TGTP GGL RE L + + + G D+MEV+P Sbjct: 229 PVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCVGDLKPV-GFDVMEVSPLYDHG 287 Query: 286 PEEVTRTVNTAVALT 300 L Sbjct: 288 GITSILATEIGAELL 302 >3PZL-A nrPDB Length = 313 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 76/313 (24%), Positives = 126/313 (40%), Gaps = 50/313 (15%) Query: 10 IIGAPFSKGQP-RGGVEKGPAALRKAGLVEKLKETEYNVR----DHGDLAFVDVPNDSPF 64 + G PF R G + P ++R A + + E Y + DL ++ D + Sbjct: 39 VFGIPFDNTSSYRRGSKYAPDSIRGAYVNLESYEYSYGIDLLASGMADLGDMEESEDVEY 98 Query: 65 QIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVD 124 I + + +VV+ +G I ++LGG+HS+ +G++ + D+ ++ VD Sbjct: 99 VI-----------DTVESVVSAVMSDGKIPIMLGGEHSITVGAVRALPK---DVDLVIVD 144 Query: 125 AHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDP 184 AH+D + + N H L L I IG+R V Sbjct: 145 AHSDFRSSYMGNKYN-HACVTRRALDLLGEG-----------------RITSIGIRSVSR 186 Query: 185 GEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPAT 244 E + + S +V K GI K +EE RK R +++S D+DG+DP + PA Sbjct: 187 EEFEDPDFRKVSFISSFDVKKNGIDKYIEEV-----DRKSRRVYISVDMDGIDPAYAPAV 241 Query: 245 GTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCF 304 GTP GL+ + + E + + G DI+E +P + A L F Sbjct: 242 GTPEPFGLADTDVRRLIERL--SYKAVGFDIVEFSPLYDNG------NTSMLAAKLLQVF 293 Query: 305 GTKREGNHKPETD 317 RE +K + Sbjct: 294 IASREKYYKEHIE 306 >3LHL-A nrPDB Length = 287 Score = 208 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 73/322 (22%), Positives = 118/322 (36%), Gaps = 55/322 (17%) Query: 1 MSSKPKPIEIIGAPFSKGQP-RGGVEKGPAALRKA-------GLVEKLKETEYNVRDHGD 52 ++ + + + G F R G +++RK L +YN+ D+GD Sbjct: 3 LNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPFLDLDLEDYNICDYGD 62 Query: 53 LAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQK---NGTISVVLGGDHSMAIGSIS 109 L SVG + L + ET K + + ++GG+H + + + Sbjct: 63 LEI----------------SVGSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFK 106 Query: 110 GHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCI 169 + D+ VI DAHTD+ S N H + + D+ G Sbjct: 107 AVHEKYNDIYVIHFDAHTDLREEYNN-SKNSHATVIK--------RIWDIVG-------- 149 Query: 170 SAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHL 229 I G+R E Y + +D E + L G+ I+L Sbjct: 150 -DNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGID------TFENIVNMLNGKN---IYL 199 Query: 230 SFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGL-LSGLDIMEVNPTLGKTPEE 288 + D+D LD P TGTP GG++YRE I + I + + + G DI+E++P T Sbjct: 200 TIDLDVLDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVS 259 Query: 289 VTRTVNTAVALTLSCFGTKREG 310 L L +EG Sbjct: 260 TVIACKILRELCLIISDKIKEG 281 >4G3H-A nrPDB Length = 330 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 70/322 (21%), Positives = 133/322 (41%), Gaps = 27/322 (8%) Query: 8 IEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIV 67 + ++G G + G +KG LR+A ++ + F+ Sbjct: 1 MILVGLEAELGASKRGTDKGVRRLREA----LSATHGDVIKGMQTITQERCVLYKEFRYA 56 Query: 68 KNPRSV-GKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPD--LCVIWVD 124 KN E L + E + ++L +H+ G VH D + ++++D Sbjct: 57 KNFEDYYLFCKENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLD 116 Query: 125 AHTDINTPLTTSSGNLHGQPVAFLLKELKGKF---PDVPGFSWVTPC----------ISA 171 AH DI+T + S ++HG P+ +L ++ F + +W C I Sbjct: 117 AHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMSESEEKAWQKLCSLGLEKGGLEIDP 176 Query: 172 KDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSF 231 K +VY G+R + E +I+ L I FS+ + + + +V+++T L + I+LS Sbjct: 177 KCLVYFGVRSTEQSERDVIRELQIPLFSVDAI-RENMQEVVQKTKESL--KAVDIIYLSL 233 Query: 232 DVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKT--GLLSGLDIMEVNPTLG--KTPE 287 D+D +D +TG GLS+ E + + ++ L +++ E NPT+ E Sbjct: 234 DLDIMDGKLFTSTGVRENNGLSFDELKQLLGLLLESFKDRLKAVEVTEYNPTVSIKHNNE 293 Query: 288 EVTRTVNTAVALTLSCFGTKRE 309 E + + + SC ++ Sbjct: 294 EEKQVLEILDLIINSCKIKDKK 315 >1WOG-A nrPDB Length = 305 Score = 186 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 76/293 (25%), Positives = 118/293 (40%), Gaps = 56/293 (19%) Query: 8 IEIIGAPFSKGQP-RGGVEKGPAALRKA---------GLVEKLKETEYNVRDHGDLAFVD 57 + +G PF R G P ALR+A GL K + D GD+ Sbjct: 31 VAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGDVI--- 87 Query: 58 VPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPD 117 +P+ P A++++ + + + V LGGDHS++ + A V PD Sbjct: 88 LPSLEPQ----------LAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFADV-PD 136 Query: 118 LCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYI 177 L V+ +DAH D T + N K+ + F C + ++V+I Sbjct: 137 LHVVQLDAHLDF-----TDTRN-------------DTKWSNSSPFRRA--CEALPNLVHI 176 Query: 178 ---GLRDV--DPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFD 232 GLR + DP + G M +V G + + L R + ++ S D Sbjct: 177 TTVGLRGLRFDPEAVAAARARGHTIIPMDDVTADLAGVLAQ------LPRGQN-VYFSVD 229 Query: 233 VDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKT 285 VDG DP P T +P GL+Y +G+ I + GLD++E+ P L T Sbjct: 230 VDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPT 282 >3M1R-A nrPDB Length = 322 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 67/296 (22%), Positives = 120/296 (40%), Gaps = 31/296 (10%) Query: 9 EIIGAPFSKGQ-PRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIV 67 +IG P SK G P +R+A LK + + G+ ++ D I Sbjct: 41 ALIGVPLSKSSISHSGASFAPGTIRQA-----LKHSSAYSAELGEHVVSELLYDLG-DID 94 Query: 68 KNPRSVGKANEQLAAVVAETQKN--GTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDA 125 + + K++ + + + + ++LGGD+S++ +I A+ VI DA Sbjct: 95 IHVTDIVKSHHHIFQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDA 154 Query: 126 HTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185 H D+ T G +G P LL E I + ++ +G+R+ Sbjct: 155 HHDVRN--TEDGGPTNGTPFRRLLDE---------------EIIEGQHLIQLGIREFSNS 197 Query: 186 EHY--IIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPA 243 + Y K + +M + + G+ ++E ++ K I +S D+D LD P Sbjct: 198 QAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILP-VVQDKTDFIFISVDMDVLDQSHAPG 256 Query: 244 TGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVAL 299 GGL E L + I + ++G++I+EV+PTL ++T V L Sbjct: 257 CPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLD--FRDMTSRAAAHVLL 310 >4RHL-A nrPDB Length = 351 Score = 157 bits (396), Expect = 7e-39, Method: Composition-based stats. Identities = 54/221 (24%), Positives = 88/221 (39%), Gaps = 36/221 (16%) Query: 82 AVVAETQKNGTISVVLGGDHSMAIGSISGHARVHP--DLCVIWVDAHTDINTPLTTSSGN 139 E + G + V +GGD S + + + R+ P D+ ++ DAH ++ P + Sbjct: 125 EASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFPSDDIVIVHFDAHPSVSDPRS----- 179 Query: 140 LHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFS 199 P+ LL + K +V +G R V + + K + Y Sbjct: 180 ----PLRVLLDKG-----------------LLKGVVSVGNRQVSSEDRKVRKLHKMFYMD 218 Query: 200 MTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLY 259 M + G+ F R P+ +S D D LDP F PA +PV GGLS R+ L+ Sbjct: 219 MHAIYSKGL-------FCIRDIRNDYPVFISIDADVLDPAFAPAVDSPVAGGLSTRDLLH 271 Query: 260 ITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 I I + G+D+ NP L ++ A++ Sbjct: 272 IMNGIRGPK-VVGIDVYGYNPDLDVYRKDNVGLTAIALSKI 311 >1XFK-A nrPDB Length = 336 Score = 94.9 bits (234), Expect = 5e-20, Method: Composition-based stats. Identities = 53/291 (18%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query: 8 IEIIGAPFSKG----QPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSP 63 + +IG G + R G + P+ +++A L + D G++ Sbjct: 45 VALIGFECDAGVERNKGRTGAKHAPSLIKQA-LANLAWHHPIPIYDLGNIRCE------- 96 Query: 64 FQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVH-------P 116 + +A ++ A V+ + + +VLGG H +A + G A+ P Sbjct: 97 ------GDELEQAQQECAQVIQQALPHARA-IVLGGGHEIAWATFQGLAQHFLATGVKQP 149 Query: 117 DLCVIWVDAHTDINTPLTT--SSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDI 174 + +I DAH D+ T + G P + + + D C+ Sbjct: 150 RIGIINFDAHFDLRTFESELAPVRPSSGTPFNQIHHFCQQQGWDFHY-----ACLGVSRA 204 Query: 175 VYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVD 234 P LG+ Y L + + + ++ ++L+ D+D Sbjct: 205 ------SNTPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFIDD--CDYLYLTIDLD 256 Query: 235 GLDPVFTPATGTPVVGGLSYREGL--YITEEIYKTGLLSGLDIMEVNPTLG 283 P P G+S E L Y ++ L DI E NP+ Sbjct: 257 VFPAASAPGVSAPAARGVSL-EALAPYFDRILHYKNKLMIADIAEYNPSFD 306 >1GKH-A nrPDB Length = 87 Score = 31.3 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 23/57 (40%) Query: 190 IKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGT 246 IK ++ + + V + G + E Y+ + P+ + +D P + P T Sbjct: 6 IKPSQAQFTTRSGVSRQGKPYSLNEQLCYVDLGNEYPVLVKITLDEGQPAYAPGLYT 62 >1QI9-A nrPDB Length = 556 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 42/122 (34%), Gaps = 11/122 (9%) Query: 59 PNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDL 118 +D+ N R ++AA E + GT+ + G+ +A H DL Sbjct: 6 SDDADDPTPPNERDDEAFASRVAAAKRELEGTGTVCQINNGETDLAAKFHKSLP--HDDL 63 Query: 119 CVIWVDA---------HTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCI 169 + DA + D++ GN G PV L+ D+ G ++ I Sbjct: 64 GQVDADAFAALEDCILNGDLSICEDVPVGNSEGDPVGRLVNPTAAFAIDISGPAFSATTI 123 Query: 170 SA 171 Sbjct: 124 PP 125 >5HP5-A nrPDB Length = 684 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 32/75 (42%), Gaps = 3/75 (4%) Query: 118 LCVIWVDAHTDINT--PLTTSSGNLHGQP-VAFLLKELKGKFPDVPGFSWVTPCISAKDI 174 +CV+ V+AH DI++ P +S + G V + + + + G + A + Sbjct: 39 VCVVGVEAHVDIHSDVPKGANSFRVSGSSGVEVFMVYNRTRVKEPIGKARWPLDTDADMV 98 Query: 175 VYIGLRDVDPGEHYI 189 V +G + + + Sbjct: 99 VSVGTASKELKDFKV 113 >3EXA-A nrPDB Length = 322 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 34/102 (33%), Gaps = 9/102 (8%) Query: 4 KPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSP 63 K K + I+G P + G+ + V ++ Y D G D Sbjct: 2 KEKLVAIVG-PTAVGKTKTSVMLAKRL--NGEVISGDSMQVYRGMDIGTAKITAEEMDGV 58 Query: 64 FQIVKNPR------SVGKANEQLAAVVAETQKNGTISVVLGG 99 + + + SV + ++ E + G + ++GG Sbjct: 59 PHHLIDIKDPSESFSVADFQDLATPLITEIHERGRLPFLVGG 100 >1JF0-A nrPDB Length = 195 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 35/100 (35%), Gaps = 8/100 (8%) Query: 46 NVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQ--------KNGTISVVL 97 ++ +G + ++ + + I KN + ++ V K L Sbjct: 30 DINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLEYGKETKFPEFL 89 Query: 98 GGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSS 137 G ++A ++ AR P L W DA DI + + Sbjct: 90 EGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGT 129 >5ED4-A nrPDB Length = 250 Score = 29.0 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 22/54 (40%) Query: 53 LAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIG 106 + V +P F +++ R+ G L ++ ++ + LGGD + Sbjct: 72 ILDVMMPGMDGFGVLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKP 125 >1KA9-F nrPDB Length = 252 Score = 28.6 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 21/58 (36%), Gaps = 3/58 (5%) Query: 45 YNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQ---LAAVVAETQKNGTISVVLGG 99 N+RD GD D + +E+ L VVA + I + +GG Sbjct: 25 VNLRDAGDPVEAARAYDEAGADELVFLDISATHEERAILLDVVARVAERVFIPLTVGG 82 >4FN5-A nrPDB Length = 709 Score = 28.2 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 2/100 (2%) Query: 56 VDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGG--DHSMAIGSISGHAR 113 ++ S +I + R A E + AV + KN + +VL D+ A I Sbjct: 241 LEEGELSEAEIKEGLRLRTLACEIVPAVCGSSFKNKGVPLVLDAVIDYLPAPTEIPAIKG 300 Query: 114 VHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELK 153 V PD + + H D N P ++ + + P L + Sbjct: 301 VSPDDETVEDERHADDNEPFSSLAFKIATDPFVGTLTFAR 340 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.122 0.316 Lambda K H 0.267 0.0376 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,790,430 Number of Sequences: 36641 Number of extensions: 453580 Number of successful extensions: 1337 Number of sequences better than 10.0: 32 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1169 Number of HSP's gapped (non-prelim): 76 length of query: 323 length of database: 10,336,785 effective HSP length: 97 effective length of query: 226 effective length of database: 6,782,608 effective search space: 1532869408 effective search space used: 1532869408 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.5 bits)