BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07711 (333 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1CJL-A nrPDB 648 0.0 3HWN-A nrPDB 541 e-154 3OF9-A nrPDB 464 e-131 2VHS-A nrPDB 410 e-115 3KFQ-A nrPDB 373 e-104 1ICF-A nrPDB 368 e-102 7PCK-A nrPDB 328 3e-90 2C0Y-A nrPDB 315 2e-86 5JA7-A nrPDB 266 1e-71 3QT4-A nrPDB 266 1e-71 2O6X-A nrPDB 264 5e-71 4BS5-A nrPDB 259 2e-69 4P6E-A nrPDB 257 4e-69 6BKI-A nrPDB 257 4e-69 3QJ3-A nrPDB 250 5e-67 5I4H-B nrPDB 234 4e-62 3F75-A nrPDB 223 9e-59 5I4H-A nrPDB 221 2e-58 1S4V-A nrPDB 221 4e-58 6CZS-A nrPDB 220 7e-58 2FO5-A nrPDB 201 3e-52 1NB3-A nrPDB 198 3e-51 5A24-A nrPDB 197 5e-51 1IWD-A nrPDB 190 7e-49 1CQD-A nrPDB 189 1e-48 2PNS-A nrPDB 187 4e-48 5EF4-A nrPDB 182 2e-46 3U8E-A nrPDB 181 4e-46 3BCN-A nrPDB 181 5e-46 1O0E-A nrPDB 178 2e-45 3P5W-A nrPDB 177 5e-45 4YYR-A nrPDB 176 1e-44 6EXO-A nrPDB 176 1e-44 1AEC-A nrPDB 176 2e-44 4YYW-A nrPDB 174 6e-44 4PI3-A nrPDB 172 2e-43 4QRX-A nrPDB 172 2e-43 2ACT-A nrPDB 170 7e-43 6MIS-A nrPDB 166 1e-41 2B1M-A nrPDB 164 4e-41 1PCI-A nrPDB 163 9e-41 1YAL-A nrPDB 163 1e-40 2BDZ-A nrPDB 163 1e-40 4YYQ-A nrPDB 155 3e-38 3BPF-A nrPDB 149 2e-36 1PPO-A nrPDB 148 3e-36 2CIO-A nrPDB 148 3e-36 1M6D-A nrPDB 147 7e-36 3IOQ-A nrPDB 147 8e-36 3BPM-A nrPDB 145 3e-35 1GEC-E nrPDB 140 9e-34 3PDF-A nrPDB 117 8e-27 1JQP-A nrPDB 116 1e-26 5JT8-A nrPDB 112 3e-25 5VPK-A nrPDB 107 6e-24 5VCN-A nrPDB 103 9e-23 1XKG-A nrPDB 100 1e-21 3PBH-A nrPDB 93 1e-19 4I05-A nrPDB 92 4e-19 1CPJ-A nrPDB 89 2e-18 5OGQ-A nrPDB 89 3e-18 4I04-A nrPDB 88 4e-18 1EF7-A nrPDB 86 2e-17 3CBK-A nrPDB 86 2e-17 1DEU-A nrPDB 86 2e-17 1MIR-A nrPDB 86 2e-17 4HWY-A nrPDB 79 2e-15 4OEL-A nrPDB 78 5e-15 4CDF-B nrPDB 77 9e-15 2DCB-A nrPDB 69 2e-12 3CH2-X nrPDB 65 5e-11 1CSB-B nrPDB 63 2e-10 1SP4-B nrPDB 59 2e-09 4CI7-A nrPDB 54 9e-08 4D59-A nrPDB 52 3e-07 4OEM-B nrPDB 49 3e-06 2L95-A nrPDB 44 1e-04 5FPW-A nrPDB 39 0.003 5WDK-A nrPDB 35 0.034 1A6R-A nrPDB 32 0.57 3OIS-A nrPDB 29 2.4 2PMB-A nrPDB 29 2.8 3FCX-A nrPDB 29 3.4 2CB5-A nrPDB 28 4.8 4A10-A nrPDB 27 9.0 4K7C-A nrPDB 27 9.9 >1CJL-A nrPDB Length = 312 Score = 648 bits (1672), Expect = 0.0, Method: Compositional matrix adjust. Identities = 307/312 (98%), Positives = 308/312 (98%) Query: 22 DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFG 81 DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFG Sbjct: 1 DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFG 60 Query: 82 DMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAF 141 DMTSEEFRQVMNG QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGS WAF Sbjct: 61 DMTSEEFRQVMNGLQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSSWAF 120 Query: 142 SATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEES 201 SATGALEGQMFRKTGRLISLSEQNLVDCSGP+GNEGCNGGLMDYAFQYVQDNGGLDSEES Sbjct: 121 SATGALEGQMFRKTGRLISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDSEES 180 Query: 202 YPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKE 261 YPYEATEESCKYNPKYSVAND GFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKE Sbjct: 181 YPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKE 240 Query: 262 GIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH 321 GIYFEPDCSSEDMDHGVLVVGYGFESTESD NKYWLVKNSWGEEWGMGGYVKMAKDRRNH Sbjct: 241 GIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKDRRNH 300 Query: 322 CGIASAASYPTV 333 CGIASAASYPTV Sbjct: 301 CGIASAASYPTV 312 >3HWN-A nrPDB Length = 258 Score = 541 bits (1393), Expect = e-154, Method: Compositional matrix adjust. Identities = 257/258 (99%), Positives = 257/258 (99%) Query: 76 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQC 135 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQC Sbjct: 1 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQC 60 Query: 136 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGG 195 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGG Sbjct: 61 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGG 120 Query: 196 LDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHES 255 LDSEESYPYEATEESCKYNPKYSVAND GFVDIPKQEKALMKAVATVGPISVAIDAGHES Sbjct: 121 LDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHES 180 Query: 256 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA Sbjct: 181 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 240 Query: 316 KDRRNHCGIASAASYPTV 333 KDRRNHCGIASAASYPTV Sbjct: 241 KDRRNHCGIASAASYPTV 258 >3OF9-A nrPDB Length = 221 Score = 464 bits (1194), Expect = e-131, Method: Compositional matrix adjust. Identities = 221/221 (100%), Positives = 221/221 (100%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQE 232 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQE Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQE 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN Sbjct: 121 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 180 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV Sbjct: 181 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >2VHS-A nrPDB Length = 217 Score = 410 bits (1054), Expect = e-115, Method: Compositional matrix adjust. Identities = 202/220 (91%), Positives = 208/220 (94%), Gaps = 3/220 (1%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 APRSVDWREKGYVTPVKNQGQCG+ +AFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVAND GFVDIPKQEK Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPKQEK 120 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 ALMKAVATVGPISVAIDAGHESFLFYKEGIYF DCSS ++H +LVVGYGF S+N Sbjct: 121 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGF---ISNNQ 177 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV Sbjct: 178 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >3KFQ-A nrPDB Length = 221 Score = 373 bits (957), Expect = e-104, Method: Compositional matrix adjust. Identities = 175/220 (79%), Positives = 194/220 (88%), Gaps = 1/220 (0%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P+SVDWR+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQG Sbjct: 2 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEK 233 N+GCNGG M AFQYV++NGGLDSEESYPY A +E CKY P+ SVA DTGF + P +EK Sbjct: 62 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGKEK 121 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 ALMKAVATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE SDN+ Sbjct: 122 ALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDNS 181 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 KYWLVKNSWG EWG GYVK+AKD+ NHCGIA+AASYP V Sbjct: 182 KYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >1ICF-A nrPDB Length = 175 Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust. Identities = 175/175 (100%), Positives = 175/175 (100%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 120 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 288 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST Sbjct: 121 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 175 >7PCK-A nrPDB Length = 314 Score = 328 bits (840), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 164/316 (51%), Positives = 213/316 (67%), Gaps = 15/316 (4%) Query: 25 LEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 83 L+ W WK H + Y +E RR +WEKN+K I +HN E G H++ +AMN GDM Sbjct: 7 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 66 Query: 84 TSEEFRQVMNGFQNRKPRKGKVFQEPLFY-----EAPRSVDWREKGYVTPVKNQGQCGSC 138 TSEE Q M G + P + L+ AP SVD+R+KGYVTPVKNQGQCGSC Sbjct: 67 TSEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSC 124 Query: 139 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS 198 WAFS+ GALEGQ+ +KTG+L++LS QNLVDC N+GC GG M AFQYVQ N G+DS Sbjct: 125 WAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDS 182 Query: 199 EESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFL 257 E++YPY EESC YNP A G+ +IP+ EKAL +AVA VGP+SVAIDA SF Sbjct: 183 EDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQ 242 Query: 258 FYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKD 317 FY +G+Y++ C+S++++H VL VGYG + NK+W++KNSWGE WG GY+ MA++ Sbjct: 243 FYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKHWIIKNSWGENWGNKGYILMARN 298 Query: 318 RRNHCGIASAASYPTV 333 + N CGIA+ AS+P + Sbjct: 299 KNNACGIANLASFPKM 314 >2C0Y-A nrPDB Length = 315 Score = 315 bits (807), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 160/324 (49%), Positives = 217/324 (66%), Gaps = 19/324 (5%) Query: 19 LTFDHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAM 77 L D +L+ W WK + + Y NEE RR +WEKN+K + LHN E+ G HS+ + M Sbjct: 2 LHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGM 61 Query: 78 NAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA------PRSVDWREKGYVTPVKN 131 N GDMTSEE +M+ R P + +Q + Y++ P SVDWREKG VT VK Sbjct: 62 NHLGDMTSEEVMSLMSSL--RVPSQ---WQRNITYKSNPNRILPDSVDWREKGCVTEVKY 116 Query: 132 QGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ-GNEGCNGGLMDYAFQYV 190 QG CG+ WAFSA GALE Q+ KTG+L+SLS QNLVDCS + GN+GCNGG M AFQY+ Sbjct: 117 QGSCGAAWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYI 176 Query: 191 QDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAI 249 DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L +AVA GP+SV + Sbjct: 177 IDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGV 236 Query: 250 DAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMG 309 DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + +YWLVKNSWG +G Sbjct: 237 DARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKNSWGHNFGEE 291 Query: 310 GYVKMAKDRRNHCGIASAASYPTV 333 GY++MA+++ NHCGIAS SYP + Sbjct: 292 GYIRMARNKGNHCGIASFPSYPEI 315 >5JA7-A nrPDB Length = 223 Score = 266 bits (679), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 128/222 (57%), Positives = 165/222 (74%), Gaps = 7/222 (3%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 AP SVD+R+KGYVTPVKNQGQCGS WAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 8 RAPDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE 67 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-Q 231 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ Sbjct: 68 --NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGN 125 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 EKAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VGYG + Sbjct: 126 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK---- 181 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 NK+W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 182 GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >3QT4-A nrPDB Length = 329 Score = 266 bits (679), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 139/315 (44%), Positives = 200/315 (63%), Gaps = 14/315 (4%) Query: 25 LEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 83 + QW+++K H + Y EE R+ +++ N+ I HN ++ +G+ +++ AMN FGDM Sbjct: 23 FQEQWSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQFGDM 82 Query: 84 TSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA---PRSVDWREKGYVTPVKNQGQCGSCWA 140 + EEF +N + +KP+ + + P SVDWR V+ VK+QGQCGS W+ Sbjct: 83 SKEEFLAYVNRGKAQKPKHPENLRMPYVSSKKPLAASVDWRSNA-VSEVKDQGQCGSSWS 141 Query: 141 FSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEE 200 FS TGA+EGQ+ + GRL SLSEQNL+DCS GN GC+GG MD AF Y+ D G+ SE Sbjct: 142 FSTTGAVEGQLALQRGRLTSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDY-GIMSES 200 Query: 201 SYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFY 259 +YPYEA + C+++ SV +G+ D+P E +L AV GP++VAIDA E FY Sbjct: 201 AYPYEAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDATDE-LQFY 259 Query: 260 KEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNK-YWLVKNSWGEEWGMGGYVKMAKDR 318 G++++ C+ D++HGVLVVGYG SDN + YW++KNSWG WG GY + ++ Sbjct: 260 SGGLFYDQTCNQSDLNHGVLVVGYG-----SDNGQDYWILKNSWGSGWGESGYWRQVRNY 314 Query: 319 RNHCGIASAASYPTV 333 N+CGIA+AASYP + Sbjct: 315 GNNCGIATAASYPAL 329 >2O6X-A nrPDB Length = 310 Score = 264 bits (674), Expect = 5e-71, Method: Compositional matrix adjust. Identities = 140/311 (45%), Positives = 182/311 (58%), Gaps = 15/311 (4%) Query: 29 WTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEF 88 W +WK M+N+ Y ++ RR +WEKN+K I+ HN + G ++T+ +N F DMT EEF Sbjct: 5 WHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEF 64 Query: 89 RQVMNGFQNRKPRKGKVFQEPLFYEA-----PRSVDWREKGYVTPVKNQGQCGSCWAFSA 143 + + R + + YEA P +DWRE GYVT VK+QG CGS WAFS Sbjct: 65 KA---KYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSGWAFST 121 Query: 144 TGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYP 203 TG +EGQ + IS SEQ LVDCS P GN GC GGLM+ A+QY++ GL++E SYP Sbjct: 122 TGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYLKQF-GLETESSYP 180 Query: 204 YEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEG 262 Y A E C+YN + VA TGF + E L V GP +VA+D F+ Y+ G Sbjct: 181 YTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDV-ESDFMMYRSG 239 Query: 263 IYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHC 322 IY CS ++H VL VGYG + YW+VKNSWG WG GY++M ++R N C Sbjct: 240 IYQSQTCSPLRVNHAVLAVGYGTQG----GTDYWIVKNSWGLSWGERGYIRMVRNRGNMC 295 Query: 323 GIASAASYPTV 333 GIAS AS P V Sbjct: 296 GIASLASLPMV 306 >4BS5-A nrPDB Length = 225 Score = 259 bits (661), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 128/222 (57%), Positives = 160/222 (72%), Gaps = 8/222 (3%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 173 P +VDWREKG VT VK QG CG+CWAFSA GALEGQ+ KTG+LISLS QNLVDCS + Sbjct: 9 PDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEK 68 Query: 174 -GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQ 231 GN+GC GG M AFQY+ DNGG++++ SYPY+A +E C YN K A + ++ +P Sbjct: 69 YGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGD 128 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E AL +AVAT GP+SV IDA H SF FYK G+Y +P C+ +++HGVLVVGYG D Sbjct: 129 EDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTG-NVNHGVLVVGYG----TLD 183 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 YWLVKNSWG +G GY++MA++ +NHCGIAS SYP + Sbjct: 184 GKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >4P6E-A nrPDB Length = 230 Score = 257 bits (657), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 123/221 (55%), Positives = 163/221 (73%), Gaps = 7/221 (3%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ- 173 P SVDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS + Sbjct: 8 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 67 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQE 232 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E Sbjct: 68 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 127 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 L +AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + Sbjct: 128 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNG 182 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 +YWLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 183 KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 223 >6BKI-A nrPDB Length = 215 Score = 257 bits (657), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 123/220 (55%), Positives = 160/220 (72%), Gaps = 7/220 (3%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P S+D+R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 2 PDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE-- 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEK 233 N GC GG M AFQYVQ NGG+DSE++YPY +ESC YN A G+ +IP EK Sbjct: 60 NYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGNEK 119 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 AL +AVA VGPISV+IDA SF FY G+Y++ +C ++++H VLVVGYG + + Sbjct: 120 ALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQK----GS 175 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 K+W++KNSWGE WG GY +A+++ N CGI + AS+P + Sbjct: 176 KHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFPKM 215 >3QJ3-A nrPDB Length = 331 Score = 250 bits (639), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 141/321 (43%), Positives = 192/321 (59%), Gaps = 25/321 (7%) Query: 28 QWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSE 86 +W +K + R Y EE +R+ +++K ++ E HN++YR+G S+T+ +N F DMT E Sbjct: 21 KWENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTLGVNLFTDMTPE 80 Query: 87 EFRQVMNGF-------QNRKPRKGKVFQEPLFYEA----PRSVDWREKGYVTPVKNQGQC 135 E + +G +N P K + E L A P S DWR++G V+PVKNQG C Sbjct: 81 EMKAYTHGLIMPADLHKNGIPIKTR---EDLGLNASVRYPASFDWRDQGMVSPVKNQGSC 137 Query: 136 GSCWAFSATGALEGQM--FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDN 193 GS WAFS+TGA+E QM G S+SEQ LVDC P GC+GG M+ AF YV N Sbjct: 138 GSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDCV-PNA-LGCSGGWMNDAFTYVAQN 195 Query: 194 GGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAIDAG 252 GG+DSE +YPYE + +C Y+P A +G+V + E L VAT GP++VA DA Sbjct: 196 GGIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVATKGPVAVAFDA- 254 Query: 253 HESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYV 312 + F Y G+Y+ P C + H VL+VGYG E+ + YWLVKNSWG+ WG+ GY Sbjct: 255 DDPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQD----YWLVKNSWGDGWGLDGYF 310 Query: 313 KMAKDRRNHCGIASAASYPTV 333 K+A++ NHCGIA AS PT+ Sbjct: 311 KIARNANNHCGIAGVASVPTL 331 >5I4H-B nrPDB Length = 112 Score = 234 bits (596), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 111/112 (99%), Positives = 111/112 (99%) Query: 222 DTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVV 281 D GFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVV Sbjct: 1 DAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVV 60 Query: 282 GYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 GYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV Sbjct: 61 GYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >3F75-A nrPDB Length = 224 Score = 223 bits (568), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 114/227 (50%), Positives = 151/227 (66%), Gaps = 8/227 (3%) Query: 110 LFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDC 169 L E P VDWR +G VTPVK+Q CGSCWAFS TGALEG KTG+L+SLSEQ L+DC Sbjct: 3 LPSELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDC 62 Query: 170 SGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP 229 S +GN+ C+GG M+ AFQYV D+GG+ SE++YPY A +E C+ V GF D+P Sbjct: 63 SRAEGNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVP 122 Query: 230 KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTE 289 ++ +A MKA P+S+AI+A F FY EG+ F+ C + D+DHGVL+VGYG T+ Sbjct: 123 RRSEAAMKAALAKSPVSIAIEADQMPFQFYHEGV-FDASCGT-DLDHGVLLVGYG---TD 177 Query: 290 SDNNK-YWLVKNSWGEEWGMGGYVKMA--KDRRNHCGIASAASYPTV 333 ++ K +W++KNSWG WG GY+ MA K CG+ AS+P + Sbjct: 178 KESKKDFWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM 224 >5I4H-A nrPDB Length = 106 Score = 221 bits (564), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 105/106 (99%), Positives = 105/106 (99%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 EAPRSVDWREKGYVTPVKNQGQCGS WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS 218 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS 106 >1S4V-A nrPDB Length = 229 Score = 221 bits (562), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 120/223 (53%), Positives = 152/223 (68%), Gaps = 12/223 (5%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P SVDWR+KG VT VK+QGQCGSCWAFS A+EG KT +L+SLSEQ LVDC Q Sbjct: 2 VPASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQ 61 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVA-NDTGFVDIPK-Q 231 N+GCNGGLMDYAF++++ GG+ +E +YPYEA + +C + + + A + G ++P+ Sbjct: 62 -NQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPEND 120 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E AL+KAVA P+SVAIDAG F FY EG+ F C +E +DHGV +VGYG T D Sbjct: 121 ENALLKAVANQ-PVSVAIDAGGSDFQFYSEGV-FTGSCGTE-LDHGVAIVGYG---TTID 174 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAK---DRRNHCGIASAASYP 331 KYW VKNSWG EWG GY++M + D+ CGIA ASYP Sbjct: 175 GTKYWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYP 217 >6CZS-A nrPDB Length = 335 Score = 220 bits (560), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 129/339 (38%), Positives = 187/339 (55%), Gaps = 23/339 (6%) Query: 3 PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59 P L A+ LG+ +A L + + + W + H + Y E R + N + I Sbjct: 6 PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65 Query: 60 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRS 117 HN G H+F MA+N F DM+ E + + + QN K + Y P S Sbjct: 66 NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119 Query: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176 VDWR+KG +V+PVKNQG CGS W FS TGALE + TG+++SL+EQ LVDC+ N Sbjct: 120 VDWRKKGNFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179 Query: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKA 234 GC GGL AF+Y+ N G+ E++YPY+ + CK+ P ++ D + I E+A Sbjct: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEA 238 Query: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDN 292 +++AVA P+S A + + F+ Y+ GIY C + + ++H VL VGYG E + Sbjct: 239 MVEAVALYNPVSFAFEVTQD-FMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331 YW+VKNSWG +WGM GY + + +N CG+A+ ASYP Sbjct: 294 IPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 331 >2FO5-A nrPDB Length = 262 Score = 201 bits (512), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 112/227 (49%), Positives = 144/227 (63%), Gaps = 17/227 (7%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P SVDWR+KG VT VK+QG+CGSCWAFS ++EG +TG L+SLSEQ L+DC Sbjct: 5 PPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTAD- 63 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY-----NPKYSVANDTGFVDIP 229 N+GC GGLMD AF+Y+++NGGL +E +YPY A +C N V D G D+P Sbjct: 64 NDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHID-GHQDVP 122 Query: 230 -KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 288 E+ L +AVA P+SVA++A ++F+FY EG+ F +C +E +DHGV VVGYG Sbjct: 123 ANSEEDLARAVANQ-PVSVAVEASGKAFMFYSEGV-FTGECGTE-LDHGVAVVGYGV--- 176 Query: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPT 332 D YW VKNSWG WG GY+++ KD CGIA ASYP Sbjct: 177 AEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPV 223 >1NB3-A nrPDB Length = 220 Score = 198 bits (503), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 100/221 (45%), Positives = 145/221 (65%), Gaps = 10/221 (4%) Query: 115 PRSVDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P S+DWR+KG +V+PVKNQG CGSCW FS TGALE + TG+++SL+EQ LVDC+ Sbjct: 2 PPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNF 61 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQE 232 N GC GGL AF+Y++ N G+ E++YPY+ ++ CK+ P ++A +I E Sbjct: 62 NNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDE 121 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTES 290 +A+++AVA P+S A + ++ FL Y++GIY C + + ++H VL VGYG E Sbjct: 122 EAMVEAVALYNPVSFAFEVTND-FLMYRKGIYSSTSCHKTPDKVNHAVLAVGYG----EE 176 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331 + YW+VKNSWG +WGM GY + + +N CG+A+ ASYP Sbjct: 177 NGIPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 216 >5A24-A nrPDB Length = 222 Score = 197 bits (502), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 109/224 (48%), Positives = 135/224 (60%), Gaps = 10/224 (4%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P +VDWR G VTPVKNQ QCG CWAFSA A+EG KTG L SLSE+ +VDC Sbjct: 2 PAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNGN 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEA---TEESCKYNPKYSVANDTGFVDIPKQ 231 ++GCNGG D AFQYV +N G+D+E YPY A + +C + A+ TG+ D+P Sbjct: 62 DKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVPAN 121 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 + ++ A PISVAIDA SF Y GIY P C++ ++DH V VVGYG + + Sbjct: 122 NEQALQQAAATQPISVAIDASDPSFQSYSSGIYSGP-CNT-NLDHAVTVVGYGTD--PNS 177 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRR---NHCGIASAASYPT 332 N YW+VKNSWG WG GY+ M CGIA ASYPT Sbjct: 178 GNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPT 221 >1IWD-A nrPDB Length = 215 Score = 190 bits (482), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 98/222 (44%), Positives = 140/222 (63%), Gaps = 14/222 (6%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P VDWR KG V +KNQ QCGSCWAFSA A+E +TG+LISLSEQ LVDC Sbjct: 2 PSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCD--TA 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQEK 233 + GCNGG M+ AFQY+ NGG+D++++YPY A + SCK P + V + GF + + + Sbjct: 60 SHGCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCK--PYRLRVVSINGFQRVTRNNE 117 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 + +++ P+SV ++A F Y GI+ P +++ +HGV++VGYG +S ++ Sbjct: 118 SALQSAVASQPVSVTVEAAGAPFQHYSSGIFTGPCGTAQ--NHGVVIVGYGTQSGKN--- 172 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPT 332 YW+V+NSWG+ WG GY+ M ++ + CGIA SYPT Sbjct: 173 -YWIVRNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYPT 213 >1CQD-A nrPDB Length = 221 Score = 189 bits (480), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 104/224 (46%), Positives = 137/224 (61%), Gaps = 13/224 (5%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 + P S+DWRE G V PVKNQG CGSCWAFS A+EG TG LISLSEQ LVDC+ Sbjct: 2 DLPDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCT-- 59 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQ- 231 N GC GG M+ AFQ++ +NGG++SEE+YPY + C V + + ++P Sbjct: 60 TANHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPSHN 119 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E++L KAVA P+SV +DA F Y+ GI F C+ +H + VVGYG TE+D Sbjct: 120 EQSLQKAVANQ-PVSVTMDAAGRDFQLYRSGI-FTGSCNIS-ANHALTVVGYG---TEND 173 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRN---HCGIASAASYPT 332 + +W+VKNSWG+ WG GY++ ++ N CGI ASYP Sbjct: 174 KD-FWIVKNSWGKNWGESGYIRAERNIENPDGKCGITRFASYPV 216 >2PNS-A nrPDB Length = 208 Score = 187 bits (476), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 105/220 (47%), Positives = 137/220 (62%), Gaps = 17/220 (7%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P +DWR+KG VTPVKNQG+CGSCWAFS +E +TG LISLSEQ LVDC+ + Sbjct: 2 PEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDCN--KK 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEK 233 N GC GG YA+QY+ DNGG+D+E +YPY+A + C+ K V G+ +P E Sbjct: 60 NHGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKK--VVRIDGYKGVPHCNEN 117 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 AL KAVA+ P VAIDA + F YK GI+ P C ++ ++HGV++VGY + Sbjct: 118 ALKKAVAS-QPSVVAIDASSKQFQHYKSGIFSGP-CGTK-LNHGVVIVGYWKD------- 167 Query: 294 KYWLVKNSWGEEWGMGGYVKMAK-DRRNHCGIASAASYPT 332 YW+V+NSWG WG GY++M + CGIA YPT Sbjct: 168 -YWIVRNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYPT 206 >5EF4-A nrPDB Length = 385 Score = 182 bits (461), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 122/321 (38%), Positives = 166/321 (51%), Gaps = 31/321 (9%) Query: 29 WTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEF 88 + +W+ HN E R V++ N++ I N+ + + + +N F DMT+ EF Sbjct: 39 YDRWREQHNIEMRSPE---RFNVFKYNVRRIHESNKMDK----PYKLKVNEFADMTNLEF 91 Query: 89 RQV-----MNGFQN-RKPRKGKVFQEP---LFY----EAPRSVDWREKGYVTPVKNQGQC 135 ++ FQ R G + +P Y + P VDWREK VT VK QG C Sbjct: 92 VNTYANSKISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVDWREKNAVTDVKGQGGC 151 Query: 136 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGG 195 GSCWAF+A ALEG +TG+L+ SEQ LVDC N GC+GGLM+ AF YV +GG Sbjct: 152 GSCWAFAAVVALEGINAIRTGKLVKFSEQQLVDCD--MTNAGCDGGLMEPAFTYVIKHGG 209 Query: 196 LDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHE 254 + E SYPY E+C V G ++P E+AL KAVA P++ I Sbjct: 210 IAPEASYPYVGKRETCDKAKIKDVLKIDGRQNVPGLDEEALRKAVAHQ-PVATGIQLSGH 268 Query: 255 SFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 FY EG+Y DC +E +HGV +VGYG K+W VKNSWG WG GY+ + Sbjct: 269 GLQFYSEGVY-TGDCGTEP-NHGVGIVGYG---ENEKGIKFWTVKNSWGPTWGEKGYIHL 323 Query: 315 AKDRRNH--CGIASAASYPTV 333 + R CG+A +S+P + Sbjct: 324 QRGARKEGLCGVAMHSSFPIM 344 >3U8E-A nrPDB Length = 222 Score = 181 bits (459), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 104/228 (45%), Positives = 133/228 (58%), Gaps = 19/228 (8%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP S+DWR+KG VT VK+QG CG CWAF ATGA+EG TGRLIS+SEQ +VDC Sbjct: 1 APASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCD--T 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 GG D AF++V NGG+ S+ +YPY + +C N + D G+ ++P Sbjct: 59 XXXXXXGGDADDAFRWVITNGGIASDANYPYTGVDGTCDLNKPIAARID-GYTNVPNSSS 117 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYK-EGIYFEPDCSSE--DMDHGVLVVGYGFESTES 290 AL+ AVA P+SV I SF Y GI+ CS + +DH VL+VGYG T + Sbjct: 118 ALLDAVAKQ-PVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTNA 176 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH------CGIASAASYPT 332 D YW+VKNSWG EWG+ GY+ + RRN C I + SYPT Sbjct: 177 D---YWIVKNSWGTEWGIDGYILI---RRNTNRPDGVCAIDAWGSYPT 218 >3BCN-A nrPDB Length = 209 Score = 181 bits (458), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 104/220 (47%), Positives = 133/220 (60%), Gaps = 17/220 (7%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P VDWR KG V P+KNQG+CGSCWAFS +E +TG LISLSEQ LVDCS + Sbjct: 2 PEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCS--KK 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEK 233 N GC GG D A+QY+ NGG+D+E +YPY+A + C+ K V G +P+ E Sbjct: 60 NHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKK--VVRIDGCKGVPQCNEN 117 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 AL AVA+ P VAIDA + F YK GI+ P C ++ ++HGV++VGYG + Sbjct: 118 ALKNAVASQ-PSVVAIDASSKQFQHYKGGIFTGP-CGTK-LNHGVVIVGYGKD------- 167 Query: 294 KYWLVKNSWGEEWGMGGYVKMAK-DRRNHCGIASAASYPT 332 YW+V+NSWG WG GY +M + CGIA YPT Sbjct: 168 -YWIVRNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYPT 206 >1O0E-A nrPDB Length = 208 Score = 178 bits (452), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 96/219 (43%), Positives = 129/219 (58%), Gaps = 15/219 (6%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P +DWR+KG VTPVKNQG CGSCWAFS +E +TG LISLSEQ LVDC + Sbjct: 2 PEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCD--KK 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKA 234 N GC GG +A+QY+ +NGG+D++ +YPY+A + C+ K V + G+ +P + Sbjct: 60 NHGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQAASK--VVSIDGYNGVPFCNEX 117 Query: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNK 294 +K V P +VAIDA F Y GI+ P C ++ ++HGV +VGY Sbjct: 118 ALKQAVAVQPSTVAIDASSAQFQQYSSGIFSGP-CGTK-LNHGVTIVGY--------QAN 167 Query: 295 YWLVKNSWGEEWGMGGYVKMAK-DRRNHCGIASAASYPT 332 YW+V+NSWG WG GY++M + CGIA YPT Sbjct: 168 YWIVRNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYPT 206 >3P5W-A nrPDB Length = 220 Score = 177 bits (449), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 98/223 (43%), Positives = 131/223 (58%), Gaps = 13/223 (5%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P VDWR G V +K+QGQCGSCWAFS A+EG TG LISLSEQ LVDC Q Sbjct: 2 PDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQN 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN---PKYSVANDTGFVDIPKQ 231 GC+GG M FQ++ +NGG+++E +YPY A E C + KY V+ DT + ++P Sbjct: 62 TRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKY-VSIDT-YENVPYN 119 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 + ++ P+SVA++A +F Y GI+ P C + +DH V +VGYG E Sbjct: 120 NEWALQTAVAYQPVSVALEAAGYNFQHYSSGIFTGP-CGTA-VDHAVTIVGYGTEG---- 173 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDR--RNHCGIASAASYPT 332 YW+VKNSWG WG GY+++ ++ CGIA ASYP Sbjct: 174 GIDYWIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYPV 216 >4YYR-A nrPDB Length = 222 Score = 176 bits (446), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 96/223 (43%), Positives = 132/223 (59%), Gaps = 12/223 (5%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P +VDWR +G V P++NQG+CGSCWAFS +EG T L SLSEQ LVDC+ Sbjct: 2 PETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCATSYK 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN-PKYSVANDTGFVDIPKQ-E 232 N GC+GG M A+ Y+ NGG+ S+ +YPY A + C + VA + +P+ E Sbjct: 62 NLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEHVPRNNE 121 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 AL AVA P+SV I+AG +F YK G+ F C ++ +DH V+ +GYG E ++ Sbjct: 122 NALKNAVAN-QPVSVTIEAGGRAFELYKSGV-FVGSCGTK-LDHAVVAIGYGSE----ND 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 YWLV+NSWG WG GY+K+ ++ CGIA ++YP Sbjct: 175 VDYWLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYPV 217 >6EXO-A nrPDB Length = 215 Score = 176 bits (445), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 104/225 (46%), Positives = 134/225 (59%), Gaps = 16/225 (7%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP +VDWREKG VTPVK+QGQCGSCWAFS G +EGQ L+SLSEQ LV C Sbjct: 1 APAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCD--T 58 Query: 174 GNEGCNGGLMDYAFQY-VQDNGG-LDSEESYPY---EATEESCKYNPKYSVANDTGFVDI 228 + GC GGLMD AF + V NGG + +E SYPY + C+ N A T VD+ Sbjct: 59 IDFGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDL 118 Query: 229 PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 288 P+ E A+ +A GP+++A+DA SF+ Y GI C+SE +DHGVL+VGY Sbjct: 119 PQDEDAIAAYLAENGPLAIAVDA--TSFMDYNGGILTS--CTSEQLDHGVLLVGY----N 170 Query: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 ++ N YW++KNSW WG GY+++ K N C + A S V Sbjct: 171 DASNPPYWIIKNSWSNMWGEDGYIRIEK-GTNQCLMNQAVSSAVV 214 >1AEC-A nrPDB Length = 218 Score = 176 bits (445), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 96/223 (43%), Positives = 131/223 (58%), Gaps = 13/223 (5%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P VDWR G V +K+QG+CG CWAFSA +EG TG LISLSEQ L+DC Q Sbjct: 2 PSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQN 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY---NPKYSVANDTGFVDIPKQ 231 GCNGG + FQ++ +NGG+++EE+YPY A + C N KY V DT + ++P Sbjct: 62 TRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKY-VTIDT-YENVPYN 119 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 + ++ T P+SVA+DA ++F Y GI+ P C + +DH V +VGYG E Sbjct: 120 NEWALQTAVTYQPVSVALDAAGDAFKQYSSGIFTGP-CGTA-IDHAVTIVGYGTEG---- 173 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDR--RNHCGIASAASYPT 332 YW+VKNSW WG GY+++ ++ CGIA+ SYP Sbjct: 174 GIDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >4YYW-A nrPDB Length = 220 Score = 174 bits (440), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 99/223 (44%), Positives = 131/223 (58%), Gaps = 12/223 (5%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P +VDWR KG V P+++QG+CGSCW FS T +EG + T L SLSEQ L+DC+ Sbjct: 2 PETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCAPSYK 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV-ANDTGFVDIPKQ-E 232 + GC GG MD A+ Y+ + G+ SE YPY A + +C V A + + D+P E Sbjct: 62 DLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPADNE 121 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 AL KAVA P+SVAIDA + Y G+ F C + DH V+VVGYG ES Sbjct: 122 DALKKAVAN-QPVSVAIDASSAAVKEYSSGV-FVGSCGVAN-DHAVVVVGYGTES----G 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRN---HCGIASAASYPT 332 YWLV+NSWG +WG GY+K+ +D + CGIA ++YP Sbjct: 175 VNYWLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYPV 217 >4PI3-A nrPDB Length = 216 Score = 172 bits (436), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 97/225 (43%), Positives = 136/225 (60%), Gaps = 16/225 (7%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP +VDWR +G VT VK+QGQCGSCWAFSA G +E Q F L +LSEQ LV C + Sbjct: 2 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCD--K 59 Query: 174 GNEGCNGGLMDYAFQYV--QDNGGLDSEESYPY---EATEESCKYNPKYSVANDTGFVDI 228 + GC+GGLM+ AF+++ ++NG + +E+SYPY E C + A TG V++ Sbjct: 60 TDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVEL 119 Query: 229 PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 288 P+ E + +A GP++VA+DA S++ Y G+ C SE +DHGVL+VGY Sbjct: 120 PQDEAQIAAWLAVNGPVAVAVDA--SSWMTYTGGVM--TSCVSEQLDHGVLLVGY----N 171 Query: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 +S YW++KNSW +WG GY+++AK N C + AS V Sbjct: 172 DSAAVPYWIIKNSWTTQWGEEGYIRIAKG-SNQCLVKEEASSAVV 215 >4QRX-A nrPDB Length = 363 Score = 172 bits (435), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 110/331 (33%), Positives = 173/331 (52%), Gaps = 28/331 (8%) Query: 12 LGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGK 70 +G + LT L + W HN++Y ++E+ +R +++ N+K I+ N++ Sbjct: 49 VGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKK----N 104 Query: 71 HSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA----PRSVDWREKGYV 126 +S+ + +N F DM+++EF++ G ++ E + + P VDWR+KG V Sbjct: 105 NSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAV 164 Query: 127 TPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYA 186 TPVKNQG CGS WAFSA +E + +TG L SEQ L+DC + + GCNGG A Sbjct: 165 TPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCD--RRSYGCNGGYPWSA 222 Query: 187 FQYVQDNGGLDSEESYPYEATEESCKYNPK--YSVANDTGFVDIPKQEKALMKAVATVGP 244 Q V G+ +YPYE + C+ K Y+ D P E AL+ ++A P Sbjct: 223 LQLVAQY-GIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIAN-QP 280 Query: 245 ISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGE 304 +SV ++A + F Y+ GI+ P C ++ +DH V VGYG Y L++NSWG Sbjct: 281 VSVVLEAAGKDFQLYRGGIFVGP-CGNK-VDHAVAAVGYG--------PNYILIRNSWGT 330 Query: 305 EWGMGGYVKMAKDRRNH---CGIASAASYPT 332 WG GY+++ + N CG+ +++ YP Sbjct: 331 GWGENGYIRIKRGTGNSYGVCGLYTSSFYPV 361 >2ACT-A nrPDB Length = 220 Score = 170 bits (431), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 91/223 (40%), Positives = 132/223 (59%), Gaps = 13/223 (5%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P VDWR G V +K+QG+CG CWAFSA +EG +G LISLSEQ L+DC Q Sbjct: 2 PSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQN 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY---NPKYSVANDTGFVDIPKQ 231 GC+GG + FQ++ ++GG+++EE+YPY A + C + KY V DT + ++P Sbjct: 62 TRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKY-VTIDT-YENVPYN 119 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 + ++ T P+SVA+DA ++F Y GI+ P C + +DH +++VGYG E Sbjct: 120 NEWALQTAVTYQPVSVALDAAGDAFKQYASGIFTGP-CGTA-VDHAIVIVGYGTEG---- 173 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDR--RNHCGIASAASYPT 332 YW+VKNSW WG GY+++ ++ CGIA+ SYP Sbjct: 174 GVDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >6MIS-A nrPDB Length = 215 Score = 166 bits (420), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 89/223 (39%), Positives = 139/223 (62%), Gaps = 14/223 (6%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P+S+DWR+ G VT VKNQG+CGSCWAF++ +E K G L+SLSEQ ++DC+ Sbjct: 2 PQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCA---V 58 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEK 233 + GC GG ++ A+ ++ N G+ S YPY+A + +CK N + A T + + + E+ Sbjct: 59 SYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNER 118 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 +M AV+ PI+ A+DA +F YK G++ P C + ++H ++++GYG +S Sbjct: 119 NMMYAVSNQ-PIAAALDA-SGNFQHYKRGVFTGP-CGTR-LNHAIVIIGYG---QDSSGK 171 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPTV 333 K+W+V+NSWG WG GGY+++A+D + CGIA YPT+ Sbjct: 172 KFWIVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPTL 214 >2B1M-A nrPDB Length = 246 Score = 164 bits (416), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 101/232 (43%), Positives = 138/232 (59%), Gaps = 19/232 (8%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 +AP S DW +KG +T VK QGQCGS WAFSATGA+E TG L+SLSEQ L+DC Sbjct: 1 DAPESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDE 60 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDI--- 228 +EGC G +F++V +GG+ SE YPY+A + CK N + V D V I Sbjct: 61 --SEGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSN 118 Query: 229 ---PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSE-DMDHGVLVVGYG 284 + ++ +++ PISV+IDA + F FY GIY +CSS ++H VL+VGYG Sbjct: 119 ESTESEAESSLQSFVLEQPISVSIDA--KDFHFYSGGIYDGGNCSSPYGINHFVLIVGYG 176 Query: 285 FESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPTV 333 E D YW+ KNSWGE+WG+ GY+++ ++ N CG+ ASYP + Sbjct: 177 SE----DGVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPII 224 >1PCI-A nrPDB Length = 322 Score = 163 bits (413), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 109/330 (33%), Positives = 173/330 (52%), Gaps = 23/330 (6%) Query: 12 LGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGK 70 +G + LT L + W HN+ Y ++E+ +R +++ N+ I+ N++ Sbjct: 5 VGYSQDDLTSTERLIQLFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETNKK----N 60 Query: 71 HSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPL---FYEAPRSVDWREKGYVT 127 +S+ + +N F D++++EF + G + +E + P +VDWR+KG VT Sbjct: 61 NSYWLGLNEFADLSNDEFNEKYVGSLIDATIEQSYDEEFINEDIVNLPENVDWRKKGAVT 120 Query: 128 PVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAF 187 PV++QG CGSCWAFSA +EG +TG+L+ LSEQ LVDC + + GC GG YA Sbjct: 121 PVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCE--RRSHGCKGGYPPYAL 178 Query: 188 QYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDI-PKQEKALMKAVATVGPI 245 +YV N G+ YPY+A + +C+ + +G + P E L+ A+A P+ Sbjct: 179 EYVAKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGNLLNAIAK-QPV 236 Query: 246 SVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEE 305 SV +++ F YK GI FE C ++ +D V V +S Y L+KNSWG Sbjct: 237 SVVVESKGRPFQLYKGGI-FEGPCGTK-VDGAVTAV----GYGKSGGKGYILIKNSWGTA 290 Query: 306 WGMGGYVKMAKDRRNH---CGIASAASYPT 332 WG GY+++ + N CG+ ++ YPT Sbjct: 291 WGEKGYIRIKRAPGNSPGVCGLYKSSYYPT 320 >1YAL-A nrPDB Length = 218 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 94/225 (41%), Positives = 131/225 (58%), Gaps = 21/225 (9%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P+S+DWR KG VTPVKNQG CGSCWAFS +EG TG L+ LSEQ LVDC + Sbjct: 2 PQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCD--KH 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC----KYNPKYSVANDTGFVDIPK 230 + GC GG + QYV +N G+ + + YPY+A + C K PK + TG+ +P Sbjct: 60 SYGCKGGYQTTSLQYVANN-GVHTSKVYPYQAKQYKCRATDKPGPKVKI---TGYKRVPS 115 Query: 231 Q-EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTE 289 E + + A+A P+SV ++AG + F YK G+ F+ C ++ +DH V VGYG Sbjct: 116 NCETSFLGALANQ-PLSVLVEAGGKPFQLYKSGV-FDGPCGTK-LDHAVTAVGYG----T 168 Query: 290 SDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYP 331 SD Y ++KNSWG WG GY+++ + N CG+ ++ YP Sbjct: 169 SDGKNYIIIKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYP 213 >2BDZ-A nrPDB Length = 214 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 97/225 (43%), Positives = 130/225 (57%), Gaps = 25/225 (11%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P S+DWREKG VTPVKNQ CGSCWAFS +EG TG+LISLSEQ L+DC + Sbjct: 2 PESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCE--RR 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC----KYNPKYSVANDTGFVDIP- 229 + GC+GG + QYV DN G+ +E YPYE + C K PK + TG+ +P Sbjct: 60 SHGCDGGYQTTSLQYVVDN-GVHTEREYPYEKKQGRCRAKDKKGPKVYI---TGYKYVPA 115 Query: 230 KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTE 289 E +L++A+A P+SV D+ F FYK GIY P C + + DH V VGYG Sbjct: 116 NDEISLIQAIANQ-PVSVVTDSRGRGFQFYKGGIYEGP-CGT-NTDHAVTAVGYG----- 167 Query: 290 SDNNKYWLVKNSWGEEWGMGGYVKMAK---DRRNHCGIASAASYP 331 Y L+KNSWG WG GY+++ + + CG+ +++ +P Sbjct: 168 ---KTYLLLKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFP 209 >4YYQ-A nrPDB Length = 217 Score = 155 bits (391), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 93/222 (41%), Positives = 131/222 (59%), Gaps = 12/222 (5%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P +VDWR KG V P++NQGQCGSCWAFSA A+E TG+L+SLSEQ L+DC+ Sbjct: 2 PETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCAQSYK 61 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEK 233 N GC GG ++ AF+Y+ N G+ S+ +YPY + C+ S+A + +P E Sbjct: 62 NLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCRTGLA-SIATIDSYQYVPSNNEN 120 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 AL AVA P+SVA++A +F YK G+ F C +DH V+++GYG + + Sbjct: 121 ALKNAVAN-QPVSVAVEAAGRAFQLYKSGV-FTGSCGVA-IDHAVVLIGYG----KYNGV 173 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 YWL++NSWG WG GY+K+ ++ CG+A YP Sbjct: 174 DYWLLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYPV 215 >3BPF-A nrPDB Length = 241 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 84/228 (36%), Positives = 137/228 (60%), Gaps = 23/228 (10%) Query: 119 DWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGC 178 DWR VTPVK+Q CGSCWAFS+ G++E Q + +LI+LSEQ LVDCS N GC Sbjct: 23 DWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFK--NYGC 80 Query: 179 NGGLMDYAFQYVQDNGGLDSEESYPYEATEESC----KYNPKYSVANDTGFVDIPKQEKA 234 NGGL++ AF+ + + GG+ + YPY + + + KY + N ++ +P + Sbjct: 81 NGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKN---YLSVP--DNK 135 Query: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFE------ST 288 L +A+ +GPIS+++ A + F FYKEGI F+ +C + ++H V++VG+G + + Sbjct: 136 LKEALRFLGPISISV-AVSDDFAFYKEGI-FDGECGDQ-LNHAVMLVGFGMKEIVNPLTK 192 Query: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRR---NHCGIASAASYPTV 333 + + + Y+++KNSWG++WG G++ + D CG+ + A P + Sbjct: 193 KGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLI 240 >1PPO-A nrPDB Length = 216 Score = 148 bits (374), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 89/223 (39%), Positives = 126/223 (56%), Gaps = 15/223 (6%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P +VDWR+KG VTPV++QG CGSCWAFSA +EG +TG+L+ LSEQ LVDC + Sbjct: 2 PENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCE--RR 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDI-PKQE 232 + GC GG YA +YV N G+ YPY+A + +C+ + +G + P E Sbjct: 60 SHGCKGGYPPYALEYVAKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNE 118 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 L+ A+A P+SV +++ F YK GI FE C ++ +DH V V +S Sbjct: 119 GNLLNAIAKQ-PVSVVVESKGRPFQLYKGGI-FEGPCGTK-VDHAVTAV----GYGKSGG 171 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPT 332 Y L+KNSWG WG GY+++ + N CG+ ++ YPT Sbjct: 172 KGYILIKNSWGTAWGEKGYIRIKRAPGNSPGVCGLYKSSYYPT 214 >2CIO-A nrPDB Length = 212 Score = 148 bits (374), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 90/223 (40%), Positives = 123/223 (55%), Gaps = 19/223 (8%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P VDWR+KG VTPVKNQG CGSCWAFSA +EG + +TG L SEQ L+DC + Sbjct: 2 PEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCD--RR 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPK--YSVANDTGFVDIPKQE 232 + GCNGG A Q V G+ +YPYE + C+ K Y+ D P E Sbjct: 60 SYGCNGGYPWSALQLVAQY-GIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNE 118 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 AL+ ++A P+SV ++A + F Y+ GI+ P C ++ +DH V VGYG Sbjct: 119 GALLYSIANQ-PVSVVLEAAGKDFQLYRGGIFVGP-CGNK-VDHAVAAVGYG-------- 167 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPT 332 Y L+KNSWG WG GY+++ + N CG+ +++ YP Sbjct: 168 PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPV 210 >1M6D-A nrPDB Length = 214 Score = 147 bits (371), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 93/222 (41%), Positives = 131/222 (59%), Gaps = 11/222 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP DWR KG VT VK+QG CGSCWAFS TG +EGQ F G L+SLSEQ L+DC + Sbjct: 1 APPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCD--K 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 ++ C GGL A+ +++ GGL++E+ Y Y+ +SC+++ + + V++ + E+ Sbjct: 59 MDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVELSQNEQ 118 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTESD 291 L +A GPISVAI+A FY+ GI P CS +DH VL+VGYG S Sbjct: 119 KLAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRS---- 172 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 + +W +KNSWG +WG GY + + CG+ + AS V Sbjct: 173 DVPFWAIKNSWGTDWGEKGYYYLHRG-SGACGVNTMASSAVV 213 >3IOQ-A nrPDB Length = 213 Score = 147 bits (370), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 93/223 (41%), Positives = 132/223 (59%), Gaps = 19/223 (8%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P S+DWR+KG VTPV+NQG CGSCW FS+ A+EG TG+L+SLSEQ L+DC + Sbjct: 2 PTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDCE--RR 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN-PKYSVANDTGFVDIPK-QE 232 + GC GG YA QYV N G+ + YPYE + C+ + K G +P+ E Sbjct: 60 SYGCRGGFPLYALQYVA-NSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRNNE 118 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 +AL++ +A + P+S+ ++A +F Y+ GI+ P +S +DH V VGYG Sbjct: 119 QALIQRIA-IQPVSIVVEAKGRAFQNYRGGIFAGPCGTS--IDHAVAAVGYG-------- 167 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRN---HCGIASAASYPT 332 N Y L+KNSWG WG GGY+++ + N CG+ S + +PT Sbjct: 168 NDYILIKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFPT 210 >3BPM-A nrPDB Length = 243 Score = 145 bits (365), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 87/228 (38%), Positives = 131/228 (57%), Gaps = 23/228 (10%) Query: 119 DWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGC 178 DWR G VTPVK+Q CGSCWAFS+ G++E Q + L SEQ LVDCS N GC Sbjct: 25 DWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCS--VKNNGC 82 Query: 179 NGGLMDYAFQYVQDNGGLDSEESYPYEAT-EESC---KYNPKYSVANDTGFVDIPKQEKA 234 GG + AF + D GGL S++ YPY + E+C + N +Y++ + +V IP + Sbjct: 83 YGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKS---YVSIP--DDK 137 Query: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNK 294 +A+ +GPIS++I A + F FY+ G Y + +C + +H V++VGYG + +++ Sbjct: 138 FKEALRYLGPISISI-AASDDFAFYRGGFY-DGECGAAP-NHAVILVGYGMKDIYNEDTG 194 Query: 295 ------YWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPTV 333 Y+++KNSWG +WG GGY+ + D + C I + A P + Sbjct: 195 RMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLL 242 >1GEC-E nrPDB Length = 216 Score = 140 bits (353), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 92/224 (41%), Positives = 121/224 (54%), Gaps = 19/224 (8%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P SVDWR KG VTPVK+QG C SCWAFS +EG KTG L+ LSEQ LVDC Sbjct: 2 PESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCD--LQ 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN----PKYSVANDTGFVDIPK 230 + GCN G + QYV N G+ YPY A +++C+ N PK N G V Sbjct: 60 SYGCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVK-TNGVGRVQ-SN 116 Query: 231 QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTES 290 E +L+ A+A P+SV +++ F YK GI FE C ++ +DH V V +S Sbjct: 117 NEGSLLNAIAH-QPVSVVVESAGRDFQNYKGGI-FEGSCGTK-VDHAVTAV----GYGKS 169 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYP 331 Y L+KNSWG WG GY+++ + N CG+ ++ YP Sbjct: 170 GGKGYILIKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYP 213 >3PDF-A nrPDB Length = 441 Score = 117 bits (292), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 90/249 (36%), Positives = 128/249 (51%), Gaps = 33/249 (13%) Query: 100 PRKGKVFQEPLFYEAPRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM--FRK 154 P ++ Q+ LF P S DWR +V+PV+NQ CGSC++F++ G LE ++ Sbjct: 195 PLTAEIQQKILF--LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTN 252 Query: 155 TGRLISLSEQNLVDCSGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK- 212 + LS Q +V CS Q +GC GG A +Y QD G L E +PY T+ CK Sbjct: 253 NSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFG-LVEEACFPYTGTDSPCKM 309 Query: 213 -------YNPKYSVANDTGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIY 264 Y+ +Y GF +ALMK + GP++VA + ++ FL YK+GIY Sbjct: 310 KEDCFRYYSSEYHYVG--GFYG--GCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIY 364 Query: 265 F-----EPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRR 319 +P E +H VL+VGYG +S + YW+VKNSWG WG GY ++ + Sbjct: 365 HHTGLRDPFNPFELTNHAVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-T 421 Query: 320 NHCGIASAA 328 + C I S A Sbjct: 422 DECAIESIA 430 >1JQP-A nrPDB Length = 438 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 85/232 (36%), Positives = 120/232 (51%), Gaps = 27/232 (11%) Query: 115 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM--FRKTGRLISLSEQNLVDC 169 P S DWR +V+PV+NQ CGSC++F++ G LE ++ + LS Q +V C Sbjct: 207 PESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSC 266 Query: 170 SGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCKYNPK------YSVAND 222 S P +GC+GG A +Y QD G ++ E +PY AT+ CK PK YS Sbjct: 267 S-PYA-QGCDGGFPYLIAGKYAQDFGVVE-ENCFPYTATDAPCK--PKENCLRYYSSEYY 321 Query: 223 TGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIYF-----EPDCSSEDMDH 276 +ALMK + GP++VA + H+ FL Y GIY +P E +H Sbjct: 322 YVGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHTGLSDPFNPFELTNH 380 Query: 277 GVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAA 328 VL+VGYG + + YW+VKNSWG +WG GY ++ + + C I S A Sbjct: 381 AVLLVGYGKDPVTGLD--YWIVKNSWGSQWGESGYFRIRRG-TDECAIESIA 429 >5JT8-A nrPDB Length = 333 Score = 112 bits (279), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 83/309 (26%), Positives = 144/309 (46%), Gaps = 22/309 (7%) Query: 5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHN 63 L++AA C +A + + ++K + ++Y EE R +++ +K +E HN Sbjct: 4 LLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHN 63 Query: 64 QEYREGKHSFTMAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPL---FYEAPRSVD 119 G A+N + DM+ +EF + G N K + +EPL + P++ D Sbjct: 64 -----GIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQNFD 118 Query: 120 WREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGN---- 175 WR+K +T ++ QG CGSCWAF+A G E + + I LSEQ LVDC+ + + Sbjct: 119 WRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDPSYQ 178 Query: 176 -EGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI--PKQE 232 GC G AF+Y+ GL E +YPY + C + + + +G+ + + Sbjct: 179 CNGCGSGYSTEAFKYMIRT-GLVEERNYPYNMRTQWCDPDVEGQRYHVSGYQQLRYHSSD 237 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + +M + GP+ + + + F G+ + DH V++VG+G Sbjct: 238 EDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWG----TVQG 293 Query: 293 NKYWLVKNS 301 YW+++NS Sbjct: 294 VDYWIIRNS 302 >5VPK-A nrPDB Length = 223 Score = 107 bits (268), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 69/202 (34%), Positives = 98/202 (48%), Gaps = 14/202 (6%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +D R VTP++ QG CGSCWAFS A E + LSEQ LVDC+ Sbjct: 11 VPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCA--- 67 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY--NPKYSVANDTGFV--DIP 229 GC+G + +Y+Q NG ++ E SYPY A E+ C+ + Y ++N D+ Sbjct: 68 SQHGCHGDTIPRGIEYIQQNGVVE-ERSYPYVAREQQCRRPNSQHYGISNYCQIYPPDVK 126 Query: 230 KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTE 289 + +AL + + I D +F Y + D + H V +VGYG ST+ Sbjct: 127 QIREALTQTHTAIAVIIGIKDL--RAFQHYDGRTIIQHDNGYQPNYHAVNIVGYG--STQ 182 Query: 290 SDNNKYWLVKNSWGEEWGMGGY 311 + YW+V+NSW WG GY Sbjct: 183 GVD--YWIVRNSWDTTWGDSGY 202 >5VCN-A nrPDB Length = 222 Score = 103 bits (257), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 97/201 (48%), Gaps = 12/201 (5%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP +D R+ VTP++ QG CGSCWAFS A E + + L+EQ LVDC+ Sbjct: 10 APAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCA--- 66 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQE 232 GC+G + +Y+Q NG + E Y Y A E+SC+ P + + I P Sbjct: 67 SQHGCHGDTIPRGIEYIQHNGVV-QESYYRYVAREQSCR-RPNAQRFGISNYCQIYPPNA 124 Query: 233 KALMKAVA-TVGPISVAIDAGH-ESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTES 290 + +A+A T I+V I ++F Y + D + H V +VGY + + Sbjct: 125 NKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGY----SNA 180 Query: 291 DNNKYWLVKNSWGEEWGMGGY 311 YW+V+NSW WG GY Sbjct: 181 QGVDYWIVRNSWDTNWGDNGY 201 >1XKG-A nrPDB Length = 312 Score = 100 bits (249), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 66/201 (32%), Positives = 96/201 (47%), Gaps = 12/201 (5%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP +D R+ VTP++ QG CGS WAFS A E + + L+EQ LVDC+ Sbjct: 90 APAEIDLRQMRTVTPIRMQGGCGSAWAFSGVAATESAYLAYRDQSLDLAEQELVDCA--- 146 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQE 232 GC+G + +Y+Q NG + E Y Y A E+SC+ P + + I P Sbjct: 147 SQHGCHGDTIPRGIEYIQHNGVV-QESYYRYVAREQSCR-RPNAQRFGISNYCQIYPPNA 204 Query: 233 KALMKAVA-TVGPISVAIDAGH-ESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTES 290 + +A+A T I+V I ++F Y + D + H V +VGY + + Sbjct: 205 NKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGY----SNA 260 Query: 291 DNNKYWLVKNSWGEEWGMGGY 311 YW+V+NSW WG GY Sbjct: 261 QGVDYWIVRNSWDTNWGDNGY 281 >3PBH-A nrPDB Length = 317 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 49/267 (18%) Query: 99 KPRKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRK 154 KP + +F E L + P S D RE+ P +++QG CGSCWAF A A+ ++ Sbjct: 51 KPPQRVMFTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIH 108 Query: 155 TGRLIS--LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSE--ESY----PY-- 204 T +S +S ++L+ C G +GCNGG A+ + G + ES+ PY Sbjct: 109 TNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSI 168 Query: 205 ----------------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVA 240 E C Y+P Y G+ + EK +M + Sbjct: 169 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 228 Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVK 299 GP+ A + FL YK G+Y + E M H + ++G+G E + YWLV Sbjct: 229 KNGPVEGAFSV-YSDFLLYKSGVYQH--VTGEMMGGHAIRILGWGVE----NGTPYWLVA 281 Query: 300 NSWGEEWGMGGYVKMAKDRRNHCGIAS 326 NSW +WG G+ K+ + ++HCGI S Sbjct: 282 NSWNTDWGDNGFFKILRG-QDHCGIES 307 >4I05-A nrPDB Length = 285 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 77/272 (28%), Positives = 120/272 (44%), Gaps = 49/272 (18%) Query: 98 RKPRKGKVFQEPLFYEAPRSVDWREK----GYVTPVKNQGQCGSCWAFSATGALEGQMFR 153 R+ R+ V E P S D R+K + +++Q +CGSCWAF A A+ + Sbjct: 18 RRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCI 77 Query: 154 KTG--RLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNG---GLDSE-----ESYP 203 ++G + + LS +L+ C G GC GG++ A+ Y G G E E YP Sbjct: 78 QSGGKQNVELSAVDLLSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYP 136 Query: 204 YEATE---------------------ESC--KYNPKYSVANDTG--FVDIPKQEKALMKA 238 + E ++C KY Y+ G ++ EKA+ K Sbjct: 137 FPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKE 196 Query: 239 VATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMD-HGVLVVGYGFESTESDNNKYWL 297 + GP+ +E FL YK GIY + E + H + ++G+G E + YWL Sbjct: 197 IMKYGPVEAGFTV-YEDFLNYKSGIY--KHITGETLGGHAIRIIGWGVE----NKAPYWL 249 Query: 298 VKNSWGEEWGMGGYVKMAKDRRNHCGIASAAS 329 + NSW E+WG GY ++ + R+ C I S + Sbjct: 250 IANSWNEDWGENGYFRIVRG-RDECSIESEVT 280 >1CPJ-A nrPDB Length = 260 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 111/250 (44%), Gaps = 45/250 (18%) Query: 115 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKT-GRL-ISLSEQNLVD 168 P S D RE+ P +++QG CGSCWAF A A+ ++ T GR+ + +S ++L+ Sbjct: 8 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 67 Query: 169 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDTG 224 C G Q +GCNGG A+ + +GG+ + T C+++ + TG Sbjct: 68 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCTG 127 Query: 225 FVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHESF 256 D PK EK +M + GP+ A F Sbjct: 128 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 186 Query: 257 LFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAK 316 L YK G+Y + + H + ++G+G E + YWLV NSW +WG G+ K+ + Sbjct: 187 LTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNADWGDNGFFKILR 241 Query: 317 DRRNHCGIAS 326 NHCGI S Sbjct: 242 G-ENHCGIES 250 >5OGQ-A nrPDB Length = 254 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 72/257 (28%), Positives = 114/257 (44%), Gaps = 49/257 (19%) Query: 113 EAPRSVDWREK----GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTG--RLISLSEQNL 166 E P S D R+K + +++Q +CGSCWAF A A+ + ++G + + LS +L Sbjct: 2 EIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVDL 61 Query: 167 VDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSE--------ESYPYEATE---------- 208 + C G GC GG++ A+ Y G + E YP+ E Sbjct: 62 LSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPC 120 Query: 209 -----------ESC--KYNPKYSVANDTG--FVDIPKQEKALMKAVATVGPISVAIDAGH 253 ++C KY Y+ G ++ EKA+ K + GP+ + Sbjct: 121 GSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV-Y 179 Query: 254 ESFLFYKEGIYFEPDCSSEDMD-HGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYV 312 E FL YK GIY + E + H + ++G+G E + YWL+ NSW E+WG GY Sbjct: 180 EDFLNYKSGIY--KHITGETLGGHAIRIIGWGVE----NKAPYWLIANSWNEDWGENGYF 233 Query: 313 KMAKDRRNHCGIASAAS 329 ++ + R+ C I S + Sbjct: 234 RIVRG-RDECSIESEVT 249 >4I04-A nrPDB Length = 323 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 76/272 (27%), Positives = 119/272 (43%), Gaps = 49/272 (18%) Query: 98 RKPRKGKVFQEPLFYEAPRSVDWREK----GYVTPVKNQGQCGSCWAFSATGALEGQMFR 153 R+ R+ V E P S D R+K + +++Q +CGS WAF A A+ + Sbjct: 56 RRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCI 115 Query: 154 KTG--RLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNG---GLDSE-----ESYP 203 ++G + + LS +L+ C G GC GG++ A+ Y G G E E YP Sbjct: 116 QSGGKQNVELSAVDLLSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYP 174 Query: 204 YEATE---------------------ESC--KYNPKYSVANDTG--FVDIPKQEKALMKA 238 + E ++C KY Y+ G ++ EKA+ K Sbjct: 175 FPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKE 234 Query: 239 VATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMD-HGVLVVGYGFESTESDNNKYWL 297 + GP+ +E FL YK GIY + E + H + ++G+G E + YWL Sbjct: 235 IMKYGPVEAGFTV-YEDFLNYKSGIY--KHITGETLGGHAIRIIGWGVE----NKAPYWL 287 Query: 298 VKNSWGEEWGMGGYVKMAKDRRNHCGIASAAS 329 + NSW E+WG GY ++ + R+ C I S + Sbjct: 288 IANSWNEDWGENGYFRIVRG-RDECSIESEVT 318 >1EF7-A nrPDB Length = 242 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 75/230 (32%), Positives = 112/230 (48%), Gaps = 45/230 (19%) Query: 115 PRSVDWREK---GYVTPVKNQG---QCGSCWAFSATGALEGQM-FRKTGRLIS--LSEQN 165 P+S DWR Y + +NQ CGSCWA ++T A+ ++ ++ G S LS QN Sbjct: 2 PKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQN 61 Query: 166 LVDCSGPQGNEG-CNGG----LMDYAFQYVQDNGGLDSEESYPYEATEESC-KYNP---- 215 ++DC GN G C GG + DYA Q+ G+ E Y+A ++ C K+N Sbjct: 62 VIDC----GNAGSCEGGNDLSVWDYAHQH-----GIPDETCNNYQAKDQECDKFNQCGTC 112 Query: 216 ----------KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYF 265 Y++ + + +EK +M + GPIS I A E Y GIY Sbjct: 113 NEFKECHAIRNYTLWRVGDYGSLSGREK-MMAEIYANGPISCGIMA-TERLANYTGGIYA 170 Query: 266 EPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 E + ++H V V G+G SD +YW+V+NSWGE WG G++++ Sbjct: 171 EYQ-DTTYINHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRIV 215 >3CBK-A nrPDB Length = 266 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 76/260 (29%), Positives = 114/260 (43%), Gaps = 49/260 (18%) Query: 106 FQEPLFYEAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGRLIS- 160 F E L + P S D RE+ P +++QG CGS WAF A A+ ++ T +S Sbjct: 1 FTEDL--KLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSV 58 Query: 161 -LSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSE--ESY----PY--------- 204 +S ++L+ C G +GCNGG A+ + G + ES+ PY Sbjct: 59 EVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHV 118 Query: 205 ---------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISV 247 E C Y+P Y G+ + EK +M + GP+ Sbjct: 119 NGARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEG 178 Query: 248 AIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVKNSWGEEW 306 A + FL YK G+Y + E M H + ++G+G E + YWLV NSW +W Sbjct: 179 AFSV-YSDFLLYKSGVYQH--VTGEMMGGHAIRILGWGVE----NGTPYWLVANSWNTDW 231 Query: 307 GMGGYVKMAKDRRNHCGIAS 326 G G+ K+ + ++HCGI S Sbjct: 232 GDNGFFKILRG-QDHCGIES 250 >1DEU-A nrPDB Length = 277 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 75/232 (32%), Positives = 113/232 (48%), Gaps = 45/232 (19%) Query: 113 EAPRSVDWREK---GYVTPVKNQG---QCGSCWAFSATGALEGQM-FRKTGRLIS--LSE 163 + P+S DWR Y + +NQ CGSCWA ++T A+ ++ ++ G S LS Sbjct: 35 DLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 94 Query: 164 QNLVDCSGPQGNEG-CNGG----LMDYAFQYVQDNGGLDSEESYPYEATEESC-KYNP-- 215 QN++DC GN G C GG + DYA Q+ G+ E Y+A ++ C K+N Sbjct: 95 QNVIDC----GNAGSCEGGNDLSVWDYAHQH-----GIPDETCNNYQAKDQECDKFNQCG 145 Query: 216 ------------KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGI 263 Y++ + + +EK +M + GPIS I A E Y GI Sbjct: 146 TCNEFKECHAIRNYTLWRVGDYGSLSGREK-MMAEIYANGPISCGIMA-TERLANYTGGI 203 Query: 264 YFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 Y E + ++H V V G+G SD +YW+V+NSWGE WG G++++ Sbjct: 204 YAEYQ-DTTYINHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRIV 250 >1MIR-A nrPDB Length = 322 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 72/250 (28%), Positives = 110/250 (44%), Gaps = 45/250 (18%) Query: 115 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKT-GRL-ISLSEQNLVD 168 P S D RE+ P +++QG CGS WAF A A+ ++ T GR+ + +S ++L+ Sbjct: 64 PESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 123 Query: 169 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDTG 224 C G Q +GCNGG A+ + +GG+ + T C+++ + TG Sbjct: 124 CCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCTG 183 Query: 225 FVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHESF 256 D PK EK +M + GP+ A F Sbjct: 184 EGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSDF 242 Query: 257 LFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAK 316 L YK G+Y + + H + ++G+G E + YWLV NSW +WG G+ K+ + Sbjct: 243 LTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNADWGDNGFFKILR 297 Query: 317 DRRNHCGIAS 326 NHCGI S Sbjct: 298 G-ENHCGIES 306 >4HWY-A nrPDB Length = 340 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 102/245 (41%), Gaps = 39/245 (15%) Query: 115 PRSVD----WREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTG-RLISLSEQNLVDC 169 P S D W + + +Q CGSCWA +A A+ + G + + +S +L+ C Sbjct: 95 PSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLAC 154 Query: 170 SGPQGNEGCNGGLMDYAFQYVQDNGGL-DSEESYPYEATEE------------------- 209 G +GCNGG D A+ Y G + D + YP+ Sbjct: 155 CSDCG-DGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNFDTP 213 Query: 210 SCKY---NPKYSVANDTGFVDIPKQ-EKALMKAVATVGPISVAIDAGHESFLFYKEGIYF 265 C Y +P V N + Q E M+ + GP VA D +E F+ Y G+Y Sbjct: 214 KCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDV-YEDFIAYNSGVYH 272 Query: 266 EPDCSSEDMD-HGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324 S + + H V +VG+G S+ YW + NSW EWGM GY + + + CGI Sbjct: 273 H--VSGQYLGGHAVRLVGWG----TSNGVPYWKIANSWNTEWGMDGYF-LIRRGSSECGI 325 Query: 325 ASAAS 329 S Sbjct: 326 EDGGS 330 >4OEL-A nrPDB Length = 370 Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 63/180 (35%), Positives = 91/180 (50%), Gaps = 25/180 (13%) Query: 100 PRKGKVFQEPLFYEAPRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEG--QMFRK 154 P ++ Q+ L P S DWR +V+PV+NQ CGSC++F++ G LE ++ Sbjct: 195 PLTAEIQQKIL--HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTN 252 Query: 155 TGRLISLSEQNLVDCSGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK- 212 + LS Q +V CS Q +GC GG A +Y QD GL E +PY T+ CK Sbjct: 253 NSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQD-FGLVEEACFPYTGTDSPCKM 309 Query: 213 -------YNPKYSVANDTGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIY 264 Y+ +Y GF +ALMK + GP++VA + ++ FL YK+GIY Sbjct: 310 KEDCFRYYSSEYHYVG--GFYG--GCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIY 364 >4CDF-B nrPDB Length = 166 Score = 77.4 bits (189), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 60/165 (36%), Positives = 85/165 (51%), Gaps = 23/165 (13%) Query: 115 PRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEG--QMFRKTGRLISLSEQNLVDC 169 P S DWR +V+PV+NQ CGSC++F++ G LE ++ + LS Q +V C Sbjct: 4 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 63 Query: 170 SGPQGNEGCNGGL-MDYAFQYVQDNGGLDSEESYPYEATEESCK--------YNPKYSVA 220 S Q +GC GG A +Y QD GL E +PY T+ CK Y+ +Y Sbjct: 64 S--QYAQGCEGGFPYLIAGKYAQDF-GLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYV 120 Query: 221 NDTGFVDIPKQEKALMKA-VATVGPISVAIDAGHESFLFYKEGIY 264 GF +ALMK + GP++VA + ++ FL YK+GIY Sbjct: 121 G--GFYG--GCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIY 160 >2DCB-A nrPDB Length = 256 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 113/251 (45%), Gaps = 47/251 (18%) Query: 115 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQM-FRKTGRL-ISLSEQNLVD 168 P S D RE+ P +++QG CGSCWAF A A+ ++ GR+ + +S ++++ Sbjct: 2 PESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLT 61 Query: 169 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDTG 224 C G + +GCNGG A+ + +GGL + + C+++ S TG Sbjct: 62 CCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTG 121 Query: 225 FVDIPK----------------------------QEKALMKAVATVGPISVAIDAGHESF 256 D PK EK +M + GP+ A + F Sbjct: 122 EGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSV-YSDF 180 Query: 257 LFYKEGIYFEPDCSSEDMD-HGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 L YK G+Y S E M H + ++G+G E + YWLV NSW +WG G+ K+ Sbjct: 181 LLYKSGVYQH--VSGEIMGGHAIRILGWGVE----NGTPYWLVGNSWNTDWGDNGFFKIL 234 Query: 316 KDRRNHCGIAS 326 + ++HCGI S Sbjct: 235 RG-QDHCGIES 244 >3CH2-X nrPDB Length = 265 Score = 64.7 bits (156), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 59/225 (26%), Positives = 93/225 (41%), Gaps = 33/225 (14%) Query: 129 VKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAF- 187 V++QG C + W F++ LE K +S + +C + + C+ G F Sbjct: 24 VEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDRCDEGSSPMEFL 83 Query: 188 QYVQDNGGLDSEESYPY---EATEESCKYNPKYSVANDTGFVDIPKQE------------ 232 Q ++D G L +E +YPY + E+ K + D G + K E Sbjct: 84 QIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGYTAY 143 Query: 233 -------------KALMKAVATVGPISVAIDAGHESFLFYK-EGIYFEPDCSSEDMDHGV 278 K + V G + I A E+ + Y+ G + C + DH V Sbjct: 144 ESERFHDNMDAFVKIIKTEVMNKGSVIAYIKA--ENVMGYEFSGKKVQNLCGDDTADHAV 201 Query: 279 LVVGYG-FESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHC 322 +VGYG + ++E + YW+V+NSWG WG GY K+ HC Sbjct: 202 NIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >1CSB-B nrPDB Length = 205 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 55/201 (27%), Positives = 85/201 (42%), Gaps = 41/201 (20%) Query: 159 ISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSE--ESY----PY-------- 204 + +S ++L+ C G +GCNGG A+ + G + ES+ PY Sbjct: 3 VEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHH 62 Query: 205 ----------EATEESCK------YNPKYSVANDTGF--VDIPKQEKALMKAVATVGPIS 246 E C Y+P Y G+ + EK +M + GP+ Sbjct: 63 VNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVE 122 Query: 247 VAIDAGHESFLFYKEGIYFEPDCSSEDM-DHGVLVVGYGFESTESDNNKYWLVKNSWGEE 305 A + FL YK G+Y + E M H + ++G+G E + YWLV NSW + Sbjct: 123 GAFSV-YSDFLLYKSGVYQH--VTGEMMGGHAIRILGWGVE----NGTPYWLVANSWNTD 175 Query: 306 WGMGGYVKMAKDRRNHCGIAS 326 WG G+ K+ + ++HCGI S Sbjct: 176 WGDNGFFKILRG-QDHCGIES 195 >1SP4-B nrPDB Length = 205 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 40/111 (36%), Positives = 57/111 (51%), Gaps = 18/111 (16%) Query: 217 YSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMD- 275 YSVAN+ EK +M + GP+ A + FL YK G+Y S E M Sbjct: 103 YSVANN---------EKEIMAEIYKNGPVEGAFSV-YSDFLLYKSGVY--QHVSGEIMGG 150 Query: 276 HGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIAS 326 H + ++G+G E + YWLV NSW +WG G+ K+ + ++HCGI S Sbjct: 151 HAIRILGWGVE----NGTPYWLVGNSWNTDWGDNGFFKILRG-QDHCGIES 196 >4CI7-A nrPDB Length = 470 Score = 53.9 bits (128), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 59/221 (26%), Positives = 91/221 (41%), Gaps = 20/221 (9%) Query: 109 PLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLV- 167 P Y++ + + + G TP KNQG + W+FS LE + K LSE++L Sbjct: 60 PSAYKSSVAYNPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRW 119 Query: 168 -DCSGPQG--NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEES------CKYNPKYS 218 G G + +G A Y+ G E+ PY E+ + + Sbjct: 120 WATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPT 179 Query: 219 VANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGV 278 N T V + K ++ + A+ G SV H S F K+ + ++H V Sbjct: 180 QFNVTDVVRLNKDKETVKNAIMQYG--SVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAV 237 Query: 279 LVVG----YGFESTESD----NNKYWLVKNSWGEEWGMGGY 311 +VG Y ++ SD +N WLVK+SWGE M G+ Sbjct: 238 AIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGF 278 >4D59-A nrPDB Length = 406 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 57/206 (27%), Positives = 84/206 (40%), Gaps = 20/206 (9%) Query: 124 GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLV--DCSGPQG--NEGCN 179 G TP KNQG + W+FS LE + K LSE++L G G + + Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMS 70 Query: 180 GGLMDYAFQYVQDNGGLDSEESYPYEATEES------CKYNPKYSVANDTGFVDIPKQEK 233 G A Y+ G E+ PY E+ + + N T V + K ++ Sbjct: 71 GSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNKDKE 130 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVG----YGFESTE 289 + A+ G SV H S F K+ + ++H V +VG Y ++ Sbjct: 131 TVKNAIMQYG--SVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKDNFA 188 Query: 290 SD----NNKYWLVKNSWGEEWGMGGY 311 SD +N WLVK+SWGE M G+ Sbjct: 189 SDVKPESNGAWLVKSSWGEFNSMKGF 214 >4OEM-B nrPDB Length = 70 Score = 48.9 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 26/61 (42%), Positives = 35/61 (57%), Gaps = 3/61 (4%) Query: 272 EDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331 E +H VL+VGYG +S + YW+VKNSWG WG GY ++ + + C I S A Sbjct: 7 ELTNHAVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-TDECAIESIAVAA 63 Query: 332 T 332 T Sbjct: 64 T 64 >2L95-A nrPDB Length = 80 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 39/63 (61%) Query: 28 QWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEE 87 +W ++K+ ++ Y E+ RR ++ ++ IE HN+++ +G+ ++ M +N D+T EE Sbjct: 9 EWVEYKSKFDKNYEAEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADLTPEE 68 Query: 88 FRQ 90 F Q Sbjct: 69 FAQ 71 >5FPW-A nrPDB Length = 321 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 11/84 (13%) Query: 243 GPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHG--VLVVGYGFESTESDNNKYWLVKN 300 GP VA+ + YK G+Y D D G V VVG+G + + YW V N Sbjct: 232 GPF-VAVFYVYTDLFAYKSGVYRHVD---GDFLGGTAVKVVGWG----KLNGTPYWKVAN 283 Query: 301 SWGEEWGMGGYVKMAKDRRNHCGI 324 +W +WGM GY+ + + N C I Sbjct: 284 TWDTDWGMDGYLLILRG-NNECNI 306 >5WDK-A nrPDB Length = 401 Score = 35.4 bits (80), Expect = 0.034, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 23/42 (54%) Query: 126 VTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLV 167 +T VKNQ + G+CW +S+ LE ++ R LSE V Sbjct: 40 ITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSEMFTV 81 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 20/29 (68%), Gaps = 3/29 (10%) Query: 275 DHGVLVVGYGFESTESDNNKYWLVKNSWG 303 DHG+ + G + + + N+Y++VKNSWG Sbjct: 335 DHGMQIYGI---AKDQEGNEYYMVKNSWG 360 >1A6R-A nrPDB Length = 471 Score = 31.6 bits (70), Expect = 0.57, Method: Compositional matrix adjust. Identities = 18/40 (45%), Positives = 19/40 (47%), Gaps = 9/40 (22%) Query: 127 TPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNL 166 TPV NQ G W F+AT L RL LSE NL Sbjct: 79 TPVTNQKSSGRAWLFAATNQL---------RLNVLSELNL 109 >3OIS-A nrPDB Length = 291 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 6/39 (15%) Query: 276 HGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 H VL VGY D +++ ++NSWG G GY M Sbjct: 237 HAVLCVGY------DDEIRHFRIRNSWGNNVGEDGYFWM 269 >2PMB-A nrPDB Length = 462 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 36/139 (25%), Positives = 49/139 (35%), Gaps = 11/139 (7%) Query: 138 CWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEG-CNGGLMDYAFQYVQDNGGL 196 CW + +E Q R+ G + L E N+ GP EG G + +A Q Sbjct: 152 CWGGHSINEVEYQYTREVGHELGLRELNICTGCGPGAMEGPMKGAAVGHAKQRY------ 205 Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATV-GPISVAIDAGHES 255 SE Y P + N+ V +P EK L V G I G Sbjct: 206 -SEYRYLGLTEPSIIAAEPPNPIVNE--LVIMPDIEKRLEAFVRMAHGIIIFPGGPGTAE 262 Query: 256 FLFYKEGIYFEPDCSSEDM 274 L Y GI P+ + + M Sbjct: 263 ELLYILGIMMHPENADQPM 281 >3FCX-A nrPDB Length = 282 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 22/55 (40%) Query: 125 YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCN 179 Y+ P G+C + + S E K+G S SE LV + GCN Sbjct: 35 YLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCN 89 >2CB5-A nrPDB Length = 453 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 11/22 (50%), Positives = 15/22 (68%) Query: 296 WLVKNSWGEEWGMGGYVKMAKD 317 W V+NSWGE+ G GY+ M + Sbjct: 391 WRVENSWGEDHGHKGYLCMTDE 412 >4A10-A nrPDB Length = 447 Score = 27.3 bits (59), Expect = 9.0, Method: Compositional matrix adjust. Identities = 10/20 (50%), Positives = 15/20 (75%) Query: 177 GCNGGLMDYAFQYVQDNGGL 196 G +GGL YA Q+V++ GG+ Sbjct: 228 GASGGLGSYAIQFVKNGGGI 247 >4K7C-A nrPDB Length = 446 Score = 27.3 bits (59), Expect = 9.9, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 7/61 (11%) Query: 258 FYKEGIYFEPDCS---SEDMDHGVLVVGYGFESTESD----NNKYWLVKNSWGEEWGMGG 310 YK+ F D + +E +D+G ++ + T D W V+NSWGE+ G G Sbjct: 336 IYKKDDLFNTDFTMTKAERLDYGESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKG 395 Query: 311 Y 311 Y Sbjct: 396 Y 396 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1CJL-A nrPDB 492 e-139 3HWN-A nrPDB 422 e-118 7PCK-A nrPDB 416 e-117 2C0Y-A nrPDB 412 e-115 6CZS-A nrPDB 387 e-108 2O6X-A nrPDB 379 e-106 3QT4-A nrPDB 378 e-105 4QRX-A nrPDB 370 e-103 3QJ3-A nrPDB 370 e-103 1PCI-A nrPDB 367 e-102 3OF9-A nrPDB 367 e-102 5EF4-A nrPDB 350 4e-97 3KFQ-A nrPDB 346 7e-96 2VHS-A nrPDB 336 6e-93 4P6E-A nrPDB 319 9e-88 5JA7-A nrPDB 316 1e-86 4BS5-A nrPDB 313 5e-86 6BKI-A nrPDB 308 3e-84 1S4V-A nrPDB 306 8e-84 3F75-A nrPDB 301 3e-82 3P5W-A nrPDB 300 5e-82 5JT8-A nrPDB 299 1e-81 2FO5-A nrPDB 298 3e-81 1CQD-A nrPDB 295 2e-80 2PNS-A nrPDB 294 4e-80 1ICF-A nrPDB 292 1e-79 1AEC-A nrPDB 292 1e-79 4YYR-A nrPDB 291 2e-79 1IWD-A nrPDB 290 4e-79 3BCN-A nrPDB 290 5e-79 1O0E-A nrPDB 288 2e-78 1NB3-A nrPDB 288 3e-78 2ACT-A nrPDB 284 4e-77 4YYW-A nrPDB 282 1e-76 5A24-A nrPDB 279 1e-75 1YAL-A nrPDB 274 4e-74 1PPO-A nrPDB 273 8e-74 2BDZ-A nrPDB 272 2e-73 6MIS-A nrPDB 267 5e-72 3U8E-A nrPDB 266 8e-72 2CIO-A nrPDB 264 3e-71 4YYQ-A nrPDB 262 2e-70 6EXO-A nrPDB 259 2e-69 2B1M-A nrPDB 257 6e-69 1GEC-E nrPDB 256 9e-69 4PI3-A nrPDB 250 7e-67 3BPF-A nrPDB 245 2e-65 3IOQ-A nrPDB 245 2e-65 3PDF-A nrPDB 239 1e-63 3BPM-A nrPDB 238 2e-63 1XKG-A nrPDB 235 2e-62 1JQP-A nrPDB 232 2e-61 1M6D-A nrPDB 232 2e-61 3PBH-A nrPDB 230 8e-61 1MIR-A nrPDB 218 3e-57 4I05-A nrPDB 216 1e-56 1CPJ-A nrPDB 216 1e-56 3CBK-A nrPDB 215 1e-56 4I04-A nrPDB 214 5e-56 5VPK-A nrPDB 209 1e-54 5VCN-A nrPDB 209 2e-54 5OGQ-A nrPDB 202 2e-52 4HWY-A nrPDB 197 6e-51 2DCB-A nrPDB 184 4e-47 5I4H-A nrPDB 184 7e-47 5I4H-B nrPDB 179 1e-45 4CI7-A nrPDB 179 2e-45 3CH2-X nrPDB 172 2e-43 4D59-A nrPDB 171 3e-43 1DEU-A nrPDB 167 9e-42 1EF7-A nrPDB 161 5e-40 4OEL-A nrPDB 160 1e-39 1CSB-B nrPDB 156 1e-38 4CDF-B nrPDB 153 7e-38 1SP4-B nrPDB 125 4e-29 4OEM-B nrPDB 91 8e-19 2L95-A nrPDB 90 9e-19 Sequences not found previously or not previously below threshold: 5FPW-A nrPDB 133 1e-31 3OIS-A nrPDB 60 1e-09 5WDK-A nrPDB 43 2e-04 4K7C-A nrPDB 41 0.001 2CB5-A nrPDB 37 0.010 1A6R-A nrPDB 36 0.022 5DMY-A nrPDB 33 0.19 2XGT-A nrPDB 30 1.2 2QGM-A nrPDB 30 1.9 2Z51-A nrPDB 30 2.0 5ZRD-A nrPDB 29 2.4 1L9N-A nrPDB 29 3.5 2OK5-A nrPDB 29 3.7 1IYW-A nrPDB 28 4.2 1V9N-A nrPDB 28 4.4 2UXY-A nrPDB 28 5.6 4MHI-A nrPDB 28 6.0 2MAR-A nrPDB 28 7.4 >1CJL-A nrPDB Length = 312 Score = 492 bits (1266), Expect = e-139, Method: Composition-based stats. Identities = 307/312 (98%), Positives = 308/312 (98%) Query: 22 DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFG 81 DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFG Sbjct: 1 DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFG 60 Query: 82 DMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAF 141 DMTSEEFRQVMNG QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGS WAF Sbjct: 61 DMTSEEFRQVMNGLQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSSWAF 120 Query: 142 SATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEES 201 SATGALEGQMFRKTGRLISLSEQNLVDCSGP+GNEGCNGGLMDYAFQYVQDNGGLDSEES Sbjct: 121 SATGALEGQMFRKTGRLISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDSEES 180 Query: 202 YPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKE 261 YPYEATEESCKYNPKYSVAND GFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKE Sbjct: 181 YPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKE 240 Query: 262 GIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH 321 GIYFEPDCSSEDMDHGVLVVGYGFESTESD NKYWLVKNSWGEEWGMGGYVKMAKDRRNH Sbjct: 241 GIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKDRRNH 300 Query: 322 CGIASAASYPTV 333 CGIASAASYPTV Sbjct: 301 CGIASAASYPTV 312 >3HWN-A nrPDB Length = 258 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 257/258 (99%), Positives = 257/258 (99%) Query: 76 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQC 135 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQC Sbjct: 1 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQC 60 Query: 136 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGG 195 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGG Sbjct: 61 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGG 120 Query: 196 LDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHES 255 LDSEESYPYEATEESCKYNPKYSVAND GFVDIPKQEKALMKAVATVGPISVAIDAGHES Sbjct: 121 LDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHES 180 Query: 256 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA Sbjct: 181 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 240 Query: 316 KDRRNHCGIASAASYPTV 333 KDRRNHCGIASAASYPTV Sbjct: 241 KDRRNHCGIASAASYPTV 258 >7PCK-A nrPDB Length = 314 Score = 416 bits (1069), Expect = e-117, Method: Composition-based stats. Identities = 165/322 (51%), Positives = 214/322 (66%), Gaps = 15/322 (4%) Query: 19 LTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAM 77 L + L+ W WK H + Y +E RR +WEKN+K I +HN E G H++ +AM Sbjct: 1 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 60 Query: 78 NAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLF-----YEAPRSVDWREKGYVTPVKNQ 132 N GDMTSEE Q M G + P + L+ AP SVD+R+KGYVTPVKNQ Sbjct: 61 NHLGDMTSEEVVQKMTGLK--VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQ 118 Query: 133 GQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQD 192 GQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC N+GC GG M AFQYVQ Sbjct: 119 GQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQK 176 Query: 193 NGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAIDA 251 N G+DSE++YPY EESC YNP A G+ +IP EKAL +AVA VGP+SVAIDA Sbjct: 177 NRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDA 236 Query: 252 GHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGY 311 SF FY +G+Y++ C+S++++H VL VGYG + NK+W++KNSWGE WG GY Sbjct: 237 SLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKHWIIKNSWGENWGNKGY 292 Query: 312 VKMAKDRRNHCGIASAASYPTV 333 + MA+++ N CGIA+ AS+P + Sbjct: 293 ILMARNKNNACGIANLASFPKM 314 >2C0Y-A nrPDB Length = 315 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 156/320 (48%), Positives = 211/320 (65%), Gaps = 9/320 (2%) Query: 18 TLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMA 76 L D +L+ W WK + + Y NEE RR +WEKN+K + LHN E+ G HS+ + Sbjct: 1 QLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLG 60 Query: 77 MNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYE-APRSVDWREKGYVTPVKNQGQC 135 MN GDMTSEE +M+ + + + + P SVDWREKG VT VK QG C Sbjct: 61 MNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSC 120 Query: 136 GSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSG-PQGNEGCNGGLMDYAFQYVQDNG 194 G+ WAFSA GALE Q+ KTG+L+SLS QNLVDCS GN+GCNGG M AFQY+ DN Sbjct: 121 GAAWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNK 180 Query: 195 GLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAIDAGH 253 G+DS+ SYPY+A ++ C+Y+ KY A + + ++P +E L +AVA GP+SV +DA H Sbjct: 181 GIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARH 240 Query: 254 ESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVK 313 SF Y+ G+Y+EP C +++++HGVLVVGYG + + +YWLVKNSWG +G GY++ Sbjct: 241 PSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKNSWGHNFGEEGYIR 295 Query: 314 MAKDRRNHCGIASAASYPTV 333 MA+++ NHCGIAS SYP + Sbjct: 296 MARNKGNHCGIASFPSYPEI 315 >6CZS-A nrPDB Length = 335 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 128/339 (37%), Positives = 184/339 (54%), Gaps = 21/339 (6%) Query: 3 PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59 P L A+ LG+ +A L + + + W + H + Y E R + N + I Sbjct: 6 PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65 Query: 60 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQV--MNGFQNRKPRKGKVFQEPLFYEAPRS 117 HN G H+F MA+N F DM+ E + + QN K + Y P S Sbjct: 66 NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119 Query: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176 VDWR+KG +V+PVKNQG CGS W FS TGALE + TG+++SL+EQ LVDC+ N Sbjct: 120 VDWRKKGNFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179 Query: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKAL 235 GC GGL AF+Y+ N G+ E++YPY+ + CK+ P ++ +I E+A+ Sbjct: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAM 239 Query: 236 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDNN 293 ++AVA P+S A + F+ Y+ GIY C + + ++H VL VGYG E + Sbjct: 240 VEAVALYNPVSFAFEVTQ-DFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNGI 294 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 332 YW+VKNSWG +WGM GY + + + N CG+A+ ASYP Sbjct: 295 PYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPI 332 >2O6X-A nrPDB Length = 310 Score = 379 bits (974), Expect = e-106, Method: Composition-based stats. Identities = 140/314 (44%), Positives = 182/314 (57%), Gaps = 15/314 (4%) Query: 26 EAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTS 85 + W +WK M+N+ Y ++ RR +WEKN+K I+ HN + G ++T+ +N F DMT Sbjct: 2 DDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTF 61 Query: 86 EEFRQVMNGFQNRKPRKGKVFQEPLFYEA-----PRSVDWREKGYVTPVKNQGQCGSCWA 140 EEF+ R + + YEA P +DWRE GYVT VK+QG CGS WA Sbjct: 62 EEFKAKY---LTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSGWA 118 Query: 141 FSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEE 200 FS TG +EGQ + IS SEQ LVDCS P GN GC GGLM+ A+QY++ GL++E Sbjct: 119 FSTTGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYLKQF-GLETES 177 Query: 201 SYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAIDAGHESFLFY 259 SYPY A E C+YN + VA TGF + E L V GP +VA+D F+ Y Sbjct: 178 SYPYTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDVES-DFMMY 236 Query: 260 KEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRR 319 + GIY CS ++H VL VGYG + YW+VKNSWG WG GY++M ++R Sbjct: 237 RSGIYQSQTCSPLRVNHAVLAVGYGTQG----GTDYWIVKNSWGLSWGERGYIRMVRNRG 292 Query: 320 NHCGIASAASYPTV 333 N CGIAS AS P V Sbjct: 293 NMCGIASLASLPMV 306 >3QT4-A nrPDB Length = 329 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 136/318 (42%), Positives = 198/318 (62%), Gaps = 12/318 (3%) Query: 21 FDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNA 79 + QW+++K H + Y EE R+ +++ N+ I HN ++ +G+ +++ AMN Sbjct: 19 PKSLFQEQWSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQ 78 Query: 80 FGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYE---APRSVDWREKGYVTPVKNQGQCG 136 FGDM+ EEF +N + +KP+ + + P SVDWR V+ VK+QGQCG Sbjct: 79 FGDMSKEEFLAYVNRGKAQKPKHPENLRMPYVSSKKPLAASVDWRS-NAVSEVKDQGQCG 137 Query: 137 SCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGL 196 S W+FS TGA+EGQ+ + GRL SLSEQNL+DCS GN GC+GG MD AF Y+ D G+ Sbjct: 138 SSWSFSTTGAVEGQLALQRGRLTSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDY-GI 196 Query: 197 DSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAIDAGHES 255 SE +YPYEA + C+++ SV +G+ D+P E +L AV GP++VAIDA E Sbjct: 197 MSESAYPYEAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDATDE- 255 Query: 256 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 FY G++++ C+ D++HGVLVVGYG + + YW++KNSWG WG GY + Sbjct: 256 LQFYSGGLFYDQTCNQSDLNHGVLVVGYGSD----NGQDYWILKNSWGSGWGESGYWRQV 311 Query: 316 KDRRNHCGIASAASYPTV 333 ++ N+CGIA+AASYP + Sbjct: 312 RNYGNNCGIATAASYPAL 329 >4QRX-A nrPDB Length = 363 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 110/331 (33%), Positives = 173/331 (52%), Gaps = 28/331 (8%) Query: 12 LGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGK 70 +G + LT L + W HN++Y ++E+ +R +++ N+K I+ N++ Sbjct: 49 VGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKK----N 104 Query: 71 HSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYE----APRSVDWREKGYV 126 +S+ + +N F DM+++EF++ G ++ E + + P VDWR+KG V Sbjct: 105 NSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAV 164 Query: 127 TPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYA 186 TPVKNQG CGS WAFSA +E + +TG L SEQ L+DC + + GCNGG A Sbjct: 165 TPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCD--RRSYGCNGGYPWSA 222 Query: 187 FQYVQDNGGLDSEESYPYEATEESCKYNPKYS-VANDTGFVDI-PKQEKALMKAVATVGP 244 Q V G+ +YPYE + C+ K A G + P E AL+ ++A P Sbjct: 223 LQLVAQY-GIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIAN-QP 280 Query: 245 ISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGE 304 +SV ++A + F Y+ GI+ P C ++ +DH V VGYG Y L++NSWG Sbjct: 281 VSVVLEAAGKDFQLYRGGIFVGP-CGNK-VDHAVAAVGYG--------PNYILIRNSWGT 330 Query: 305 EWGMGGYVKMAKDRRNH---CGIASAASYPT 332 WG GY+++ + N CG+ +++ YP Sbjct: 331 GWGENGYIRIKRGTGNSYGVCGLYTSSFYPV 361 >3QJ3-A nrPDB Length = 331 Score = 370 bits (949), Expect = e-103, Method: Composition-based stats. Identities = 140/333 (42%), Positives = 192/333 (57%), Gaps = 25/333 (7%) Query: 16 SATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFT 74 + + +W +K + R Y EE +R+ +++K ++ E HN++YR+G S+T Sbjct: 9 EGSALPSTFVAEKWENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYT 68 Query: 75 MAMNAFGDMTSEEFRQVMNGF-------QNRKPRKGKVFQEPLFYEA----PRSVDWREK 123 + +N F DMT EE + +G +N P K +E L A P S DWR++ Sbjct: 69 LGVNLFTDMTPEEMKAYTHGLIMPADLHKNGIPIKT---REDLGLNASVRYPASFDWRDQ 125 Query: 124 GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLI--SLSEQNLVDCSGPQGNEGCNGG 181 G V+PVKNQG CGS WAFS+TGA+E QM G S+SEQ LVDC GC+GG Sbjct: 126 GMVSPVKNQGSCGSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDCVP--NALGCSGG 183 Query: 182 LMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVA 240 M+ AF YV NGG+DSE +YPYE + +C Y+P A +G+V + E L VA Sbjct: 184 WMNDAFTYVAQNGGIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVA 243 Query: 241 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN 300 T GP++VA DA + F Y G+Y+ P C + H VL+VGYG E + YWLVKN Sbjct: 244 TKGPVAVAFDA-DDPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNE----NGQDYWLVKN 298 Query: 301 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 SWG+ WG+ GY K+A++ NHCGIA AS PT+ Sbjct: 299 SWGDGWGLDGYFKIARNANNHCGIAGVASVPTL 331 >1PCI-A nrPDB Length = 322 Score = 367 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 108/330 (32%), Positives = 173/330 (52%), Gaps = 23/330 (6%) Query: 12 LGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGK 70 +G + LT L + W HN+ Y ++E+ +R +++ N+ I+ N++ Sbjct: 5 VGYSQDDLTSTERLIQLFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETNKK----N 60 Query: 71 HSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPL---FYEAPRSVDWREKGYVT 127 +S+ + +N F D++++EF + G + +E + P +VDWR+KG VT Sbjct: 61 NSYWLGLNEFADLSNDEFNEKYVGSLIDATIEQSYDEEFINEDIVNLPENVDWRKKGAVT 120 Query: 128 PVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAF 187 PV++QG CGSCWAFSA +EG +TG+L+ LSEQ LVDC + + GC GG YA Sbjct: 121 PVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDC--ERRSHGCKGGYPPYAL 178 Query: 188 QYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDI-PKQEKALMKAVATVGPI 245 +YV N G+ YPY+A + +C+ + +G + P E L+ A+A P+ Sbjct: 179 EYVAKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGNLLNAIAK-QPV 236 Query: 246 SVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEE 305 SV +++ F YK GI+ P C ++ +D V V +S Y L+KNSWG Sbjct: 237 SVVVESKGRPFQLYKGGIFEGP-CGTK-VDGAVTAV----GYGKSGGKGYILIKNSWGTA 290 Query: 306 WGMGGYVKMAKDRRNH---CGIASAASYPT 332 WG GY+++ + N CG+ ++ YPT Sbjct: 291 WGEKGYIRIKRAPGNSPGVCGLYKSSYYPT 320 >3OF9-A nrPDB Length = 221 Score = 367 bits (942), Expect = e-102, Method: Composition-based stats. Identities = 221/221 (100%), Positives = 221/221 (100%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQE 232 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQE Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQE 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN Sbjct: 121 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 180 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV Sbjct: 181 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >5EF4-A nrPDB Length = 385 Score = 350 bits (899), Expect = 4e-97, Method: Composition-based stats. Identities = 120/336 (35%), Positives = 164/336 (48%), Gaps = 31/336 (9%) Query: 14 IASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSF 73 L + + +W+ HN E R V++ N++ I N+ + + Sbjct: 24 YHERELESEEGFMGMYDRWREQHNIEMRSPE---RFNVFKYNVRRIHESNKMDK----PY 76 Query: 74 TMAMNAFGDMTSEEFRQVMNGFQN------RKPRKGKVFQEPL-------FYEAPRSVDW 120 + +N F DMT+ EF + R G + +P + P VDW Sbjct: 77 KLKVNEFADMTNLEFVNTYANSKISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVDW 136 Query: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180 REK VT VK QG CGSCWAF+A ALEG +TG+L+ SEQ LVDC N GC+G Sbjct: 137 REKNAVTDVKGQGGCGSCWAFAAVVALEGINAIRTGKLVKFSEQQLVDCD--MTNAGCDG 194 Query: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAV 239 GLM+ AF YV +GG+ E SYPY E+C V G ++P E+AL KAV Sbjct: 195 GLMEPAFTYVIKHGGIAPEASYPYVGKRETCDKAKIKDVLKIDGRQNVPGLDEEALRKAV 254 Query: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299 A P++ I FY EG+Y DC +E +HGV +VGYG K+W VK Sbjct: 255 A-HQPVATGIQLSGHGLQFYSEGVYTG-DCGTEP-NHGVGIVGYG---ENEKGIKFWTVK 308 Query: 300 NSWGEEWGMGGYVKMAKDRR--NHCGIASAASYPTV 333 NSWG WG GY+ + + R CG+A +S+P + Sbjct: 309 NSWGPTWGEKGYIHLQRGARKEGLCGVAMHSSFPIM 344 >3KFQ-A nrPDB Length = 221 Score = 346 bits (888), Expect = 7e-96, Method: Composition-based stats. Identities = 175/221 (79%), Positives = 194/221 (87%), Gaps = 1/221 (0%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P+SVDWR+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQ Sbjct: 1 LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQE 232 GN+GCNGG M AFQYV++NGGLDSEESYPY A +E CKY P+ SVA DTGF + P +E Sbjct: 61 GNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGKE 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 KALMKAVATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE SDN Sbjct: 121 KALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDN 180 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 +KYWLVKNSWG EWG GYVK+AKD+ NHCGIA+AASYP V Sbjct: 181 SKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >2VHS-A nrPDB Length = 217 Score = 336 bits (863), Expect = 6e-93, Method: Composition-based stats. Identities = 202/220 (91%), Positives = 208/220 (94%), Gaps = 3/220 (1%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 APRSVDWREKGYVTPVKNQGQCG+ +AFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVAND GFVDIPKQEK Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPKQEK 120 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 ALMKAVATVGPISVAIDAGHESFLFYKEGIYF DCSS ++H +LVVGYGF S+N Sbjct: 121 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGF---ISNNQ 177 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV Sbjct: 178 KYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >4P6E-A nrPDB Length = 230 Score = 319 bits (818), Expect = 9e-88, Method: Composition-based stats. Identities = 123/222 (55%), Positives = 162/222 (72%), Gaps = 7/222 (3%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSG-P 172 P SVDWREKG VT VK QG CG+CWAFSA GALE Q+ KTG+L+SLS QNLVDCS Sbjct: 7 LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEK 66 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQ 231 GN+GCNGG M AFQY+ DN G+DS+ SYPY+A ++ C+Y+ KY A + + ++P + Sbjct: 67 YGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGR 126 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E L +AVA GP+SV +DA H SF Y+ G+Y+EP C +++++HGVLVVGYG + + Sbjct: 127 EDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLN 181 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 +YWLVKNSWG +G GY++MA+++ NHCGIAS SYP + Sbjct: 182 GKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 223 >5JA7-A nrPDB Length = 223 Score = 316 bits (809), Expect = 1e-86, Method: Composition-based stats. Identities = 128/226 (56%), Positives = 164/226 (72%), Gaps = 7/226 (3%) Query: 109 PLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVD 168 AP SVD+R+KGYVTPVKNQGQCGS WAFS+ GALEGQ+ +KTG+L++LS QNLVD Sbjct: 4 EWEGRAPDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQNLVD 63 Query: 169 CSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI 228 C N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +I Sbjct: 64 CVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREI 121 Query: 229 P-KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 287 P EKAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VGYG + Sbjct: 122 PEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK 181 Query: 288 TESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 NK+W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 182 ----GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >4BS5-A nrPDB Length = 225 Score = 313 bits (803), Expect = 5e-86, Method: Composition-based stats. Identities = 128/223 (57%), Positives = 159/223 (71%), Gaps = 8/223 (3%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCS--G 171 P +VDWREKG VT VK QG CG+CWAFSA GALEGQ+ KTG+LISLS QNLVDCS Sbjct: 8 LPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEE 67 Query: 172 PQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-K 230 GN+GC GG M AFQY+ DNGG++++ SYPY+A +E C YN K A + ++ +P Sbjct: 68 KYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFG 127 Query: 231 QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTES 290 E AL +AVAT GP+SV IDA H SF FYK G+Y +P C+ +++HGVLVVGYG Sbjct: 128 DEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTG-NVNHGVLVVGYGT----L 182 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 D YWLVKNSWG +G GY++MA++ +NHCGIAS SYP + Sbjct: 183 DGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >6BKI-A nrPDB Length = 215 Score = 308 bits (788), Expect = 3e-84, Method: Composition-based stats. Identities = 123/221 (55%), Positives = 160/221 (72%), Gaps = 7/221 (3%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P S+D+R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 VPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE- 59 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQE 232 N GC GG M AFQYVQ NGG+DSE++YPY +ESC YN A G+ +IP E Sbjct: 60 -NYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGNE 118 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 KAL +AVA VGPISV+IDA SF FY G+Y++ +C ++++H VLVVGYG + Sbjct: 119 KALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQK----G 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 +K+W++KNSWGE WG GY +A+++ N CGI + AS+P + Sbjct: 175 SKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFPKM 215 >1S4V-A nrPDB Length = 229 Score = 306 bits (784), Expect = 8e-84, Method: Composition-based stats. Identities = 117/224 (52%), Positives = 147/224 (65%), Gaps = 12/224 (5%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P SVDWR+KG VT VK+QGQCGSCWAFS A+EG KT +L+SLSEQ LVDC Q Sbjct: 2 VPASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQ 61 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN-PKYSVANDTGFVDIP-KQ 231 N+GCNGGLMDYAF++++ GG+ +E +YPYEA + +C + + G ++P Sbjct: 62 -NQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPEND 120 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E AL+KAVA P+SVAIDAG F FY EG++ C +E +DHGV +VGYG T D Sbjct: 121 ENALLKAVAN-QPVSVAIDAGGSDFQFYSEGVFTG-SCGTE-LDHGVAIVGYG---TTID 174 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 KYW VKNSWG EWG GY++M + + CGIA ASYP Sbjct: 175 GTKYWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPI 218 >3F75-A nrPDB Length = 224 Score = 301 bits (771), Expect = 3e-82, Method: Composition-based stats. Identities = 110/226 (48%), Positives = 148/226 (65%), Gaps = 6/226 (2%) Query: 110 LFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDC 169 L E P VDWR +G VTPVK+Q CGSCWAFS TGALEG KTG+L+SLSEQ L+DC Sbjct: 3 LPSELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDC 62 Query: 170 SGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP 229 S +GN+ C+GG M+ AFQYV D+GG+ SE++YPY A +E C+ V GF D+P Sbjct: 63 SRAEGNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVP 122 Query: 230 KQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTE 289 ++ +A MKA P+S+AI+A F FY EG++ + C ++ +DHGVL+VGYG + + Sbjct: 123 RRSEAAMKAALAKSPVSIAIEADQMPFQFYHEGVF-DASCGTD-LDHGVLLVGYGTD--K 178 Query: 290 SDNNKYWLVKNSWGEEWGMGGYVKMA--KDRRNHCGIASAASYPTV 333 +W++KNSWG WG GY+ MA K CG+ AS+P + Sbjct: 179 ESKKDFWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM 224 >3P5W-A nrPDB Length = 220 Score = 300 bits (769), Expect = 5e-82, Method: Composition-based stats. Identities = 93/222 (41%), Positives = 127/222 (57%), Gaps = 9/222 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P VDWR G V +K+QGQCGSCWAFS A+EG TG LISLSEQ LVDC Q Sbjct: 1 LPDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN-PKYSVANDTGFVDIPKQE 232 GC+GG M FQ++ +NGG+++E +YPY A E C + + + + ++P Sbjct: 61 NTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYENVPYNN 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + ++ P+SVA++A +F Y GI+ P C + +DH V +VGYG E Sbjct: 121 EWALQTAVAYQPVSVALEAAGYNFQHYSSGIFTGP-CGTA-VDHAVTIVGYGTEG----G 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRR--NHCGIASAASYPT 332 YW+VKNSWG WG GY+++ ++ CGIA ASYP Sbjct: 175 IDYWIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYPV 216 >5JT8-A nrPDB Length = 333 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 95/341 (27%), Positives = 161/341 (47%), Gaps = 23/341 (6%) Query: 5 LILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHN 63 L++AA C +A + + ++K + ++Y EE R +++ +K +E HN Sbjct: 4 LLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHN 63 Query: 64 QEYREGKHSFTMAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPL---FYEAPRSVD 119 G A+N + DM+ +EF + G N K + +EPL + P++ D Sbjct: 64 -----GIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQNFD 118 Query: 120 WREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGN---- 175 WR+K +T ++ QG CGSCWAF+A G E + + I LSEQ LVDC+ + + Sbjct: 119 WRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDPSYQ 178 Query: 176 -EGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI--PKQE 232 GC G AF+Y+ GL E +YPY + C + + + +G+ + + Sbjct: 179 CNGCGSGYSTEAFKYMIRT-GLVEERNYPYNMRTQWCDPDVEGQRYHVSGYQQLRYHSSD 237 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + +M + GP+ + + + F G+ + DH V++VG+G Sbjct: 238 EDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGT----VQG 293 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 YW+++NSWG WG GGY + + N GI + +Y T+ Sbjct: 294 VDYWIIRNSWGTGWGNGGYGYVERGH-NSLGINNYVTYATL 333 >2FO5-A nrPDB Length = 262 Score = 298 bits (763), Expect = 3e-81, Method: Composition-based stats. Identities = 109/230 (47%), Positives = 144/230 (62%), Gaps = 15/230 (6%) Query: 111 FYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCS 170 + P SVDWR+KG VT VK+QG+CGSCWAFS ++EG +TG L+SLSEQ L+DC Sbjct: 1 VSDLPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCD 60 Query: 171 GPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCK----YNPKYSVANDTGFV 226 N+GC GGLMD AF+Y+++NGGL +E +YPY A +C V + G Sbjct: 61 TAD-NDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQ 119 Query: 227 DIPKQ-EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGF 285 D+P E+ L +AVA P+SVA++A ++F+FY EG++ +C +E +DHGV VVGYG Sbjct: 120 DVPANSEEDLARAVAN-QPVSVAVEASGKAFMFYSEGVFTG-ECGTE-LDHGVAVVGYGV 176 Query: 286 ESTESDNNKYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 D YW VKNSWG WG GY+++ KD CGIA ASYP Sbjct: 177 ---AEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPV 223 >1CQD-A nrPDB Length = 221 Score = 295 bits (755), Expect = 2e-80, Method: Composition-based stats. Identities = 95/223 (42%), Positives = 129/223 (57%), Gaps = 11/223 (4%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 + P S+DWRE G V PVKNQG CGSCWAFS A+EG TG LISLSEQ LVDC+ Sbjct: 2 DLPDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCTTA 61 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQE 232 N GC GG M+ AFQ++ +NGG++SEE+YPY + C V + + ++P Sbjct: 62 --NHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPSHN 119 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + ++ P+SV +DA F Y+ GI+ S +H + VVGYG E ++ Sbjct: 120 EQSLQKAVANQPVSVTMDAAGRDFQLYRSGIFTGSCNISA--NHALTVVGYGTE----ND 173 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRN---HCGIASAASYPT 332 +W+VKNSWG+ WG GY++ ++ N CGI ASYP Sbjct: 174 KDFWIVKNSWGKNWGESGYIRAERNIENPDGKCGITRFASYPV 216 >2PNS-A nrPDB Length = 208 Score = 294 bits (753), Expect = 4e-80, Method: Composition-based stats. Identities = 99/220 (45%), Positives = 130/220 (59%), Gaps = 15/220 (6%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +DWR+KG VTPVKNQG+CGSCWAFS +E +TG LISLSEQ LVDC + Sbjct: 1 LPEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDC--NK 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 N GC GG YA+QY+ DNGG+D+E +YPY+A + C+ K V G+ +P + Sbjct: 59 KNHGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKK--VVRIDGYKGVPHCNE 116 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 +K P VAIDA + F YK GI+ P C ++ ++HGV++VGY Sbjct: 117 NALKKAVASQPSVVAIDASSKQFQHYKSGIFSGP-CGTK-LNHGVVIVGYW--------K 166 Query: 294 KYWLVKNSWGEEWGMGGYVKMAK-DRRNHCGIASAASYPT 332 YW+V+NSWG WG GY++M + CGIA YPT Sbjct: 167 DYWIVRNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYPT 206 >1ICF-A nrPDB Length = 175 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 175/175 (100%), Positives = 175/175 (100%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 120 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 288 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST Sbjct: 121 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 175 >1AEC-A nrPDB Length = 218 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 90/222 (40%), Positives = 126/222 (56%), Gaps = 9/222 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P VDWR G V +K+QG+CG CWAFSA +EG TG LISLSEQ L+DC Q Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN-PKYSVANDTGFVDIPKQE 232 GCNGG + FQ++ +NGG+++EE+YPY A + C + + ++P Sbjct: 61 NTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYNN 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + ++ T P+SVA+DA ++F Y GI+ P C + +DH V +VGYG E Sbjct: 121 EWALQTAVTYQPVSVALDAAGDAFKQYSSGIFTGP-CGTA-IDHAVTIVGYGTEG----G 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRR--NHCGIASAASYPT 332 YW+VKNSW WG GY+++ ++ CGIA+ SYP Sbjct: 175 IDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >4YYR-A nrPDB Length = 222 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 90/223 (40%), Positives = 129/223 (57%), Gaps = 10/223 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +VDWR +G V P++NQG+CGSCWAFS +EG T L SLSEQ LVDC+ Sbjct: 1 LPETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCATSY 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN-PKYSVANDTGFVDIPKQE 232 N GC+GG M A+ Y+ NGG+ S+ +YPY A + C + VA + +P+ Sbjct: 61 KNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEHVPRNN 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + +K P+SV I+AG +F YK G++ C ++ +DH V+ +GYG E ++ Sbjct: 121 ENALKNAVANQPVSVTIEAGGRAFELYKSGVFVG-SCGTK-LDHAVVAIGYGSE----ND 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 YWLV+NSWG WG GY+K+ ++ CGIA ++YP Sbjct: 175 VDYWLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYPV 217 >1IWD-A nrPDB Length = 215 Score = 290 bits (743), Expect = 4e-79, Method: Composition-based stats. Identities = 98/222 (44%), Positives = 135/222 (60%), Gaps = 12/222 (5%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P VDWR KG V +KNQ QCGSCWAFSA A+E +TG+LISLSEQ LVDC Sbjct: 1 LPSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCDTA- 59 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 + GCNGG M+ AFQY+ NGG+D++++YPY A + SCK + V + GF + + + Sbjct: 60 -SHGCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCKPY-RLRVVSINGFQRVTRNNE 117 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 + +++ P+SV ++A F Y GI+ P C + +HGV++VGYG +S Sbjct: 118 SALQSAVASQPVSVTVEAAGAPFQHYSSGIFTGP-CGTAQ-NHGVVIVGYGTQS----GK 171 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 YW+V+NSWG+ WG GY+ M ++ CGIA SYPT Sbjct: 172 NYWIVRNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYPT 213 >3BCN-A nrPDB Length = 209 Score = 290 bits (743), Expect = 5e-79, Method: Composition-based stats. Identities = 99/220 (45%), Positives = 128/220 (58%), Gaps = 15/220 (6%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P VDWR KG V P+KNQG+CGSCWAFS +E +TG LISLSEQ LVDCS + Sbjct: 1 LPEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCS--K 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 N GC GG D A+QY+ NGG+D+E +YPY+A + C+ K V G +P+ + Sbjct: 59 KNHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKK--VVRIDGCKGVPQCNE 116 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 +K P VAIDA + F YK GI+ P C ++ ++HGV++VGYG Sbjct: 117 NALKNAVASQPSVVAIDASSKQFQHYKGGIFTGP-CGTK-LNHGVVIVGYG--------K 166 Query: 294 KYWLVKNSWGEEWGMGGYVKMAK-DRRNHCGIASAASYPT 332 YW+V+NSWG WG GY +M + CGIA YPT Sbjct: 167 DYWIVRNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYPT 206 >1O0E-A nrPDB Length = 208 Score = 288 bits (738), Expect = 2e-78, Method: Composition-based stats. Identities = 96/220 (43%), Positives = 129/220 (58%), Gaps = 15/220 (6%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +DWR+KG VTPVKNQG CGSCWAFS +E +TG LISLSEQ LVDC + Sbjct: 1 LPEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCD--K 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 N GC GG +A+QY+ +NGG+D++ +YPY+A + C+ K V + G+ +P + Sbjct: 59 KNHGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQAASK--VVSIDGYNGVPFCNE 116 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 +K V P +VAIDA F Y GI+ P C ++ ++HGV +VGY Sbjct: 117 XALKQAVAVQPSTVAIDASSAQFQQYSSGIFSGP-CGTK-LNHGVTIVGY--------QA 166 Query: 294 KYWLVKNSWGEEWGMGGYVKMAK-DRRNHCGIASAASYPT 332 YW+V+NSWG WG GY++M + CGIA YPT Sbjct: 167 NYWIVRNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYPT 206 >1NB3-A nrPDB Length = 220 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 100/222 (45%), Positives = 144/222 (64%), Gaps = 10/222 (4%) Query: 115 PRSVDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P S+DWR+KG +V+PVKNQG CGSCW FS TGALE + TG+++SL+EQ LVDC+ Sbjct: 2 PPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNF 61 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQE 232 N GC GGL AF+Y++ N G+ E++YPY+ ++ CK+ P ++A +I E Sbjct: 62 NNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDE 121 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTES 290 +A+++AVA P+S A + + FL Y++GIY C + + ++H VL VGYG E Sbjct: 122 EAMVEAVALYNPVSFAFEVTN-DFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEE---- 176 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPT 332 + YW+VKNSWG +WGM GY + + + N CG+A+ ASYP Sbjct: 177 NGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPI 217 >2ACT-A nrPDB Length = 220 Score = 284 bits (727), Expect = 4e-77, Method: Composition-based stats. Identities = 86/222 (38%), Positives = 126/222 (56%), Gaps = 9/222 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P VDWR G V +K+QG+CG CWAFSA +EG +G LISLSEQ L+DC Q Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQ 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN-PKYSVANDTGFVDIPKQE 232 GC+GG + FQ++ ++GG+++EE+YPY A + C + ++P Sbjct: 61 NTRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKYVTIDTYENVPYNN 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + ++ T P+SVA+DA ++F Y GI+ P C + +DH +++VGYG E Sbjct: 121 EWALQTAVTYQPVSVALDAAGDAFKQYASGIFTGP-CGTA-VDHAIVIVGYGTEG----G 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRR--NHCGIASAASYPT 332 YW+VKNSW WG GY+++ ++ CGIA+ SYP Sbjct: 175 VDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >4YYW-A nrPDB Length = 220 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 92/223 (41%), Positives = 126/223 (56%), Gaps = 10/223 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +VDWR KG V P+++QG+CGSCW FS T +EG + T L SLSEQ L+DC+ Sbjct: 1 LPETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCAPSY 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS-VANDTGFVDIPKQE 232 + GC GG MD A+ Y+ + G+ SE YPY A + +C VA + + D+P Sbjct: 61 KDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPADN 120 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + +K P+SVAIDA + Y G++ C + DH V+VVGYG ES Sbjct: 121 EDALKKAVANQPVSVAIDASSAAVKEYSSGVFVG-SCGVAN-DHAVVVVGYGTES----G 174 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 YWLV+NSWG +WG GY+K+ +D CGIA ++YP Sbjct: 175 VNYWLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYPV 217 >5A24-A nrPDB Length = 222 Score = 279 bits (714), Expect = 1e-75, Method: Composition-based stats. Identities = 108/225 (48%), Positives = 133/225 (59%), Gaps = 10/225 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +VDWR G VTPVKNQ QCG CWAFSA A+EG KTG L SLSE+ +VDC Sbjct: 1 VPAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNG 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEA---TEESCKYNPKYSVANDTGFVDIPK 230 ++GCNGG D AFQYV +N G+D+E YPY A + +C + A+ TG+ D+P Sbjct: 61 NDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVPA 120 Query: 231 QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTES 290 + ++ A PISVAIDA SF Y GIY P + ++DH V VVGYG + + Sbjct: 121 NNEQALQQAAATQPISVAIDASDPSFQSYSSGIYSGPCNT--NLDHAVTVVGYGTDP--N 176 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRR---NHCGIASAASYPT 332 N YW+VKNSWG WG GY+ M CGIA ASYPT Sbjct: 177 SGNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPT 221 >1YAL-A nrPDB Length = 218 Score = 274 bits (701), Expect = 4e-74, Method: Composition-based stats. Identities = 91/222 (40%), Positives = 129/222 (58%), Gaps = 15/222 (6%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P+S+DWR KG VTPVKNQG CGSCWAFS +EG TG L+ LSEQ LVDC + Sbjct: 2 PQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCD--KH 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY-NPKYSVANDTGFVDIPKQ-E 232 + GC GG + QYV +N G+ + + YPY+A + C+ + TG+ +P E Sbjct: 60 SYGCKGGYQTTSLQYVANN-GVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNCE 118 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + + A+A P+SV ++AG + F YK G++ P C ++ +DH V VGYG SD Sbjct: 119 TSFLGALAN-QPLSVLVEAGGKPFQLYKSGVFDGP-CGTK-LDHAVTAVGYGT----SDG 171 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYP 331 Y ++KNSWG WG GY+++ + N CG+ ++ YP Sbjct: 172 KNYIIIKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYP 213 >1PPO-A nrPDB Length = 216 Score = 273 bits (698), Expect = 8e-74, Method: Composition-based stats. Identities = 88/224 (39%), Positives = 126/224 (56%), Gaps = 15/224 (6%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +VDWR+KG VTPV++QG CGSCWAFSA +EG +TG+L+ LSEQ LVDC + Sbjct: 1 LPENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDC--ER 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDI-PKQ 231 + GC GG YA +YV N G+ YPY+A + +C+ + +G + P Sbjct: 59 RSHGCKGGYPPYALEYVAKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNN 117 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E L+ A+A P+SV +++ F YK GI+ P C ++ +DH V V +S Sbjct: 118 EGNLLNAIAK-QPVSVVVESKGRPFQLYKGGIFEGP-CGTK-VDHAVTAV----GYGKSG 170 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPT 332 Y L+KNSWG WG GY+++ + N CG+ ++ YPT Sbjct: 171 GKGYILIKNSWGTAWGEKGYIRIKRAPGNSPGVCGLYKSSYYPT 214 >2BDZ-A nrPDB Length = 214 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 91/222 (40%), Positives = 123/222 (55%), Gaps = 17/222 (7%) Query: 115 PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQG 174 P S+DWREKG VTPVKNQ CGSCWAFS +EG TG+LISLSEQ L+DC + Sbjct: 2 PESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDC--ERR 59 Query: 175 NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY-NPKYSVANDTGFVDIPKQEK 233 + GC+GG + QYV DN G+ +E YPYE + C+ + K TG+ +P ++ Sbjct: 60 SHGCDGGYQTTSLQYVVDN-GVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPANDE 118 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 + P+SV D+ F FYK GIY P C + + DH V VGYG Sbjct: 119 ISLIQAIANQPVSVVTDSRGRGFQFYKGGIYEGP-CGT-NTDHAVTAVGYG--------K 168 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRR---NHCGIASAASYPT 332 Y L+KNSWG WG GY+++ + CG+ +++ +P Sbjct: 169 TYLLLKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPI 210 >6MIS-A nrPDB Length = 215 Score = 267 bits (683), Expect = 5e-72, Method: Composition-based stats. Identities = 86/223 (38%), Positives = 134/223 (60%), Gaps = 12/223 (5%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P+S+DWR+ G VT VKNQG+CGSCWAF++ +E K G L+SLSEQ ++DC+ Sbjct: 1 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAV-- 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 + GC GG ++ A+ ++ N G+ S YPY+A + +CK N + A T + + + + Sbjct: 59 -SYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNE 117 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 M + PI+ A+DA +F YK G++ P C + ++H ++++GYG + S Sbjct: 118 RNMMYAVSNQPIAAALDASG-NFQHYKRGVFTGP-CGTR-LNHAIVIIGYGQD---SSGK 171 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKDRR---NHCGIASAASYPTV 333 K+W+V+NSWG WG GGY+++A+D CGIA YPT+ Sbjct: 172 KFWIVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPTL 214 >3U8E-A nrPDB Length = 222 Score = 266 bits (681), Expect = 8e-72, Method: Composition-based stats. Identities = 102/225 (45%), Positives = 132/225 (58%), Gaps = 13/225 (5%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP S+DWR+KG VT VK+QG CG CWAF ATGA+EG TGRLIS+SEQ +VDC Sbjct: 1 APASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCDTXX 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 GG D AF++V NGG+ S+ +YPY + +C N K A G+ ++P Sbjct: 61 XXX--XGGDADDAFRWVITNGGIASDANYPYTGVDGTCDLN-KPIAARIDGYTNVPNSSS 117 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKE-GIYFEPDCSSED--MDHGVLVVGYGFESTES 290 AL+ AVA P+SV I SF Y GI+ CS + +DH VL+VGYG T + Sbjct: 118 ALLDAVAK-QPVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTNA 176 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRR---NHCGIASAASYPT 332 D YW+VKNSWG EWG+ GY+ + ++ C I + SYPT Sbjct: 177 D---YWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYPT 218 >2CIO-A nrPDB Length = 212 Score = 264 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 90/224 (40%), Positives = 123/224 (54%), Gaps = 19/224 (8%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P VDWR+KG VTPVKNQG CGSCWAFSA +EG + +TG L SEQ L+DC + Sbjct: 1 IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCD--R 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS-VANDTGFVDI-PKQ 231 + GCNGG A Q V G+ +YPYE + C+ K A G + P Sbjct: 59 RSYGCNGGYPWSALQLVAQY-GIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYN 117 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E AL+ ++A P+SV ++A + F Y+ GI+ P C ++ +DH V VGYG Sbjct: 118 EGALLYSIAN-QPVSVVLEAAGKDFQLYRGGIFVGP-CGNK-VDHAVAAVGYG------- 167 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPT 332 Y L+KNSWG WG GY+++ + N CG+ +++ YP Sbjct: 168 -PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPV 210 >4YYQ-A nrPDB Length = 217 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 87/222 (39%), Positives = 128/222 (57%), Gaps = 10/222 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P +VDWR KG V P++NQGQCGSCWAFSA A+E TG+L+SLSEQ L+DC+ Sbjct: 1 LPETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCAQSY 60 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 N GC GG ++ AF+Y+ N G+ S+ +YPY + C+ S+A + +P + Sbjct: 61 KNLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCRTGLA-SIATIDSYQYVPSNNE 119 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNN 293 +K P+SVA++A +F YK G++ C +DH V+++GYG + + Sbjct: 120 NALKNAVANQPVSVAVEAAGRAFQLYKSGVFTG-SCGVA-IDHAVVLIGYG----KYNGV 173 Query: 294 KYWLVKNSWGEEWGMGGYVKMAKD---RRNHCGIASAASYPT 332 YWL++NSWG WG GY+K+ ++ CG+A YP Sbjct: 174 DYWLLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYPV 215 >6EXO-A nrPDB Length = 215 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 103/225 (45%), Positives = 135/225 (60%), Gaps = 16/225 (7%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP +VDWREKG VTPVK+QGQCGSCWAFS G +EGQ L+SLSEQ LV C Sbjct: 1 APAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTI- 59 Query: 174 GNEGCNGGLMDYAFQYVQD-NGG-LDSEESYPY---EATEESCKYNPKYSVANDTGFVDI 228 + GC GGLMD AF ++ + NGG + +E SYPY + C+ N A T VD+ Sbjct: 60 -DFGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDL 118 Query: 229 PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 288 P+ E A+ +A GP+++A+DA SF+ Y GI C+SE +DHGVL+VGY Sbjct: 119 PQDEDAIAAYLAENGPLAIAVDAT--SFMDYNGGILT--SCTSEQLDHGVLLVGY----N 170 Query: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 ++ N YW++KNSW WG GY+++ K N C + A S V Sbjct: 171 DASNPPYWIIKNSWSNMWGEDGYIRIEKG-TNQCLMNQAVSSAVV 214 >2B1M-A nrPDB Length = 246 Score = 257 bits (656), Expect = 6e-69, Method: Composition-based stats. Identities = 97/232 (41%), Positives = 134/232 (57%), Gaps = 19/232 (8%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 +AP S DW +KG +T VK QGQCGS WAFSATGA+E TG L+SLSEQ L+DC Sbjct: 1 DAPESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDE 60 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFV------ 226 +EGC G +F++V +GG+ SE YPY+A + CK N + Sbjct: 61 --SEGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSN 118 Query: 227 -DIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSED-MDHGVLVVGYG 284 + ++ +++ PISV+IDA + F FY GIY +CSS ++H VL+VGYG Sbjct: 119 ESTESEAESSLQSFVLEQPISVSIDA--KDFHFYSGGIYDGGNCSSPYGINHFVLIVGYG 176 Query: 285 FESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPTV 333 E D YW+ KNSWGE+WG+ GY+++ ++ N CG+ ASYP + Sbjct: 177 SE----DGVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPII 224 >1GEC-E nrPDB Length = 216 Score = 256 bits (655), Expect = 9e-69, Method: Composition-based stats. Identities = 87/224 (38%), Positives = 118/224 (52%), Gaps = 15/224 (6%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P SVDWR KG VTPVK+QG C SCWAFS +EG KTG L+ LSEQ LVDC Sbjct: 1 LPESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCDLQ- 59 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDI-PKQ 231 + GCN G + QYV N G+ YPY A +++C+ N G + Sbjct: 60 -SYGCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVKTNGVGRVQSNN 117 Query: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291 E +L+ A+A P+SV +++ F YK GI+ E C ++ +DH V V +S Sbjct: 118 EGSLLNAIA-HQPVSVVVESAGRDFQNYKGGIF-EGSCGTK-VDHAVTAV----GYGKSG 170 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNH---CGIASAASYPT 332 Y L+KNSWG WG GY+++ + N CG+ ++ YP Sbjct: 171 GKGYILIKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYPI 214 >4PI3-A nrPDB Length = 216 Score = 250 bits (638), Expect = 7e-67, Method: Composition-based stats. Identities = 97/225 (43%), Positives = 134/225 (59%), Gaps = 16/225 (7%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP +VDWR +G VT VK+QGQCGSCWAFSA G +E Q F L +LSEQ LV C Sbjct: 2 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKT- 60 Query: 174 GNEGCNGGLMDYAFQYVQ--DNGGLDSEESYPY---EATEESCKYNPKYSVANDTGFVDI 228 + GC+GGLM+ AF+++ +NG + +E+SYPY E C + A TG V++ Sbjct: 61 -DSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVEL 119 Query: 229 PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFEST 288 P+ E + +A GP++VA+DA S++ Y G+ C SE +DHGVL+VGY Sbjct: 120 PQDEAQIAAWLAVNGPVAVAVDAS--SWMTYTGGVMT--SCVSEQLDHGVLLVGY----N 171 Query: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 +S YW++KNSW +WG GY+++AK N C + AS V Sbjct: 172 DSAAVPYWIIKNSWTTQWGEEGYIRIAKG-SNQCLVKEEASSAVV 215 >3BPF-A nrPDB Length = 241 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 81/228 (35%), Positives = 135/228 (59%), Gaps = 17/228 (7%) Query: 116 RSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGN 175 + DWR VTPVK+Q CGSCWAFS+ G++E Q + +LI+LSEQ LVDCS N Sbjct: 20 AAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCS--FKN 77 Query: 176 EGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEES-CKYNPKYSVANDTGFVDIPKQEKA 234 GCNGGL++ AF+ + + GG+ + YPY + + C + ++ +P + Sbjct: 78 YGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVP--DNK 135 Query: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFE------ST 288 L +A+ +GPIS+++ A + F FYKEGI+ + +C + ++H V++VG+G + + Sbjct: 136 LKEALRFLGPISISV-AVSDDFAFYKEGIF-DGECGDQ-LNHAVMLVGFGMKEIVNPLTK 192 Query: 289 ESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRN---HCGIASAASYPTV 333 + + + Y+++KNSWG++WG G++ + D CG+ + A P + Sbjct: 193 KGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLI 240 >3IOQ-A nrPDB Length = 213 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 89/223 (39%), Positives = 126/223 (56%), Gaps = 17/223 (7%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 P S+DWR+KG VTPV+NQG CGSCW FS+ A+EG TG+L+SLSEQ L+DC + Sbjct: 1 IPTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDC--ER 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQE 232 + GC GG YA QYV N G+ + YPYE + C+ + K G +P+ Sbjct: 59 RSYGCRGGFPLYALQYVA-NSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRNN 117 Query: 233 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 292 + + + P+S+ ++A +F Y+ GI+ P C + +DH V VGYG Sbjct: 118 EQALIQRIAIQPVSIVVEAKGRAFQNYRGGIFAGP-CGTS-IDHAVAAVGYG-------- 167 Query: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRN---HCGIASAASYPT 332 N Y L+KNSWG WG GGY+++ + N CG+ S + +PT Sbjct: 168 NDYILIKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFPT 210 >3PDF-A nrPDB Length = 441 Score = 239 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 94/314 (29%), Positives = 149/314 (47%), Gaps = 34/314 (10%) Query: 41 GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKP 100 ++E + +++ + ++ N + + M + +T + + G + P Sbjct: 133 KNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYM---EYETLTLGDMIRRSGGHSRKIP 189 Query: 101 R------KGKVFQEPLFYEAPRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM 151 R ++ Q+ LF P S DWR +V+PV+NQ CGSC++F++ G LE ++ Sbjct: 190 RPKPAPLTAEIQQKILF--LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARI 247 Query: 152 FRKTG--RLISLSEQNLVDCSGPQGNEGCNGGLM-DYAFQYVQDNGGLDSEESYPYEATE 208 T + LS Q +V CS Q +GC GG A +Y QD GL E +PY T+ Sbjct: 248 RILTNNSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDF-GLVEEACFPYTGTD 304 Query: 209 ESCKYNPKYSVANDTGFVDIPK----QEKALMK-AVATVGPISVAIDAGHESFLFYKEGI 263 CK + + + +ALMK + GP++VA + ++ FL YK+GI Sbjct: 305 SPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGI 363 Query: 264 YF-----EPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDR 318 Y +P E +H VL+VGYG +S + YW+VKNSWG WG GY ++ + Sbjct: 364 YHHTGLRDPFNPFELTNHAVLLVGYGTDS--ASGMDYWIVKNSWGTGWGENGYFRIRRG- 420 Query: 319 RNHCGIASAASYPT 332 + C I S A T Sbjct: 421 TDECAIESIAVAAT 434 >3BPM-A nrPDB Length = 243 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 84/227 (37%), Positives = 125/227 (55%), Gaps = 17/227 (7%) Query: 117 SVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176 + DWR G VTPVK+Q CGSCWAFS+ G++E Q + L SEQ LVDCS N Sbjct: 23 AYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVK--NN 80 Query: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEAT-EESCKYNPKYSVANDTGFVDIPKQEKAL 235 GC GG + AF + D GGL S++ YPY + E+C +V IP + Sbjct: 81 GCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIP--DDKF 138 Query: 236 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNK- 294 +A+ +GPIS++I A + F FY+ G +++ +C + +H V++VGYG + +++ Sbjct: 139 KEALRYLGPISISI-AASDDFAFYRGG-FYDGECGAAP-NHAVILVGYGMKDIYNEDTGR 195 Query: 295 -----YWLVKNSWGEEWGMGGYVKMAKDRRN---HCGIASAASYPTV 333 Y+++KNSWG +WG GGY+ + D C I + A P + Sbjct: 196 MEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLL 242 >1XKG-A nrPDB Length = 312 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 78/301 (25%), Positives = 130/301 (43%), Gaps = 33/301 (10%) Query: 23 HSLEAQWTKWKAMHNRLYGM--NEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAF 80 S + ++K N+ Y +EE R+ + +++K ++ + A+N Sbjct: 2 PSSIKTFEEYKKAFNKSYATFEDEEAARKN-FLESVKYVQSNGG-----------AINHL 49 Query: 81 GDMTSEEFRQVM-------NGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQG 133 D++ +EF+ + + + + AP +D R+ VTP++ QG Sbjct: 50 SDLSLDEFKNRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQG 109 Query: 134 QCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDN 193 CGS WAFS A E + + L+EQ LVDC+ GC+G + +Y+Q N Sbjct: 110 GCGSAWAFSGVAATESAYLAYRDQSLDLAEQELVDCAS---QHGCHGDTIPRGIEYIQHN 166 Query: 194 GGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAVAT-VGPISVAIDA 251 G+ E Y Y A E+SC+ P + + I P + +A+A I+V I Sbjct: 167 -GVVQESYYRYVAREQSCR-RPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGI 224 Query: 252 GH-ESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGG 310 ++F Y + D + H V +VGY + + YW+V+NSW WG G Sbjct: 225 KDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGY----SNAQGVDYWIVRNSWDTNWGDNG 280 Query: 311 Y 311 Y Sbjct: 281 Y 281 >1JQP-A nrPDB Length = 438 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 86/246 (34%), Positives = 122/246 (49%), Gaps = 25/246 (10%) Query: 99 KPRKGKVFQEPLFYEAPRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQMFRKT 155 P ++ Q+ L P S DWR +V+PV+NQ CGSC++F++ G LE ++ T Sbjct: 193 APITDEIQQQIL--SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILT 250 Query: 156 G--RLISLSEQNLVDCSGPQGNEGCNGGLM-DYAFQYVQDNGGLDSEESYPYEATEESCK 212 + LS Q +V CS +GC+GG A +Y QD G+ E +PY AT+ CK Sbjct: 251 NNSQTPILSPQEVVSCSP--YAQGCDGGFPYLIAGKYAQDF-GVVEENCFPYTATDAPCK 307 Query: 213 YNPK----YSVANDTGFVDIPKQEKALMK-AVATVGPISVAIDAGHESFLFYKEGIYF-- 265 YS +ALMK + GP++VA + H+ FL Y GIY Sbjct: 308 PKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGIYHHT 366 Query: 266 ---EPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHC 322 +P E +H VL+VGYG + YW+VKNSWG +WG GY ++ + + C Sbjct: 367 GLSDPFNPFELTNHAVLLVGYGKDPVT--GLDYWIVKNSWGSQWGESGYFRIRRG-TDEC 423 Query: 323 GIASAA 328 I S A Sbjct: 424 AIESIA 429 >1M6D-A nrPDB Length = 214 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 93/222 (41%), Positives = 131/222 (59%), Gaps = 11/222 (4%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 173 AP DWR KG VT VK+QG CGSCWAFS TG +EGQ F G L+SLSEQ L+DC + Sbjct: 1 APPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCD--K 58 Query: 174 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEK 233 ++ C GGL A+ +++ GGL++E+ Y Y+ +SC+++ + + V++ + E+ Sbjct: 59 MDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVELSQNEQ 118 Query: 234 ALMKAVATVGPISVAIDAGHESFLFYKEGIYF--EPDCSSEDMDHGVLVVGYGFESTESD 291 L +A GPISVAI+A FY+ GI P CS +DH VL+VGYG S Sbjct: 119 KLAAWLAKRGPISVAINAFG--MQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRS---- 172 Query: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 + +W +KNSWG +WG GY + + CG+ + AS V Sbjct: 173 DVPFWAIKNSWGTDWGEKGYYYLHRG-SGACGVNTMASSAVV 213 >3PBH-A nrPDB Length = 317 Score = 230 bits (586), Expect = 8e-61, Method: Composition-based stats. Identities = 79/311 (25%), Positives = 130/311 (41%), Gaps = 56/311 (18%) Query: 56 MKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNR-KPRKGKVFQEPLFYEA 114 + + N ++ G + + + DM+ +++ F KP + +F E L + Sbjct: 15 VNYVNKRNTTWQAGHNFYNV------DMSY--LKRLCGTFLGGPKPPQRVMFTEDL--KL 64 Query: 115 PRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGRLIS--LSEQNLVD 168 P S D RE+ P +++QG CGSCWAF A A+ ++ T +S +S ++L+ Sbjct: 65 PASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLT 124 Query: 169 CSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCK------------ 212 C G +GCNGG A+ + +GGL + C+ Sbjct: 125 CCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTG 184 Query: 213 --------------YNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAGHESF 256 Y+P Y G+ + EK +M + GP+ A + F Sbjct: 185 EGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YSDF 243 Query: 257 LFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAK 316 L YK G+Y H + ++G+G E + YWLV NSW +WG G+ K+ + Sbjct: 244 LLYKSGVYQHVT-GEMMGGHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFKILR 298 Query: 317 DRRNHCGIASA 327 ++HCGI S Sbjct: 299 G-QDHCGIESE 308 >1MIR-A nrPDB Length = 322 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 75/312 (24%), Positives = 126/312 (40%), Gaps = 54/312 (17%) Query: 54 KNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYE 113 + I N ++ G++ + + ++ + + + G P+ + Sbjct: 12 DMINYINKQNTTWQAGRNFYNVDIS---------YLKKLCGTVLGGPKLPERVGFSEDIN 62 Query: 114 APRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGR--LISLSEQNLV 167 P S D RE+ P +++QG CGS WAF A A+ ++ T + +S ++L+ Sbjct: 63 LPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 122 Query: 168 DCSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDT 223 C G Q +GCNGG A+ + +GG+ + T C+++ + T Sbjct: 123 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCT 182 Query: 224 GFVDIPKQ----------------------------EKALMKAVATVGPISVAIDAGHES 255 G D PK EK +M + GP+ A Sbjct: 183 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FSD 241 Query: 256 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 FL YK G+Y + + H + ++G+G E + YWLV NSW +WG G+ K+ Sbjct: 242 FLTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNADWGDNGFFKIL 296 Query: 316 KDRRNHCGIASA 327 + NHCGI S Sbjct: 297 RGE-NHCGIESE 307 >4I05-A nrPDB Length = 285 Score = 216 bits (551), Expect = 1e-56, Method: Composition-based stats. Identities = 74/271 (27%), Positives = 116/271 (42%), Gaps = 47/271 (17%) Query: 98 RKPRKGKVFQEPLFYEAPRSVDWREKGY----VTPVKNQGQCGSCWAFSATGALEGQMFR 153 R+ R+ V E P S D R+K + +++Q +CGSCWAF A A+ + Sbjct: 18 RRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCI 77 Query: 154 KTG--RLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLD--------SEESYP 203 ++G + + LS +L+ C G GC GG++ A+ Y G + E YP Sbjct: 78 QSGGKQNVELSAVDLLSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYP 136 Query: 204 YEATE---------------------ESC--KYNPKYSVANDTGF--VDIPKQEKALMKA 238 + E ++C KY Y+ G ++ EKA+ K Sbjct: 137 FPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKE 196 Query: 239 VATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLV 298 + GP+ +E FL YK GIY H + ++G+G E + YWL+ Sbjct: 197 IMKYGPVEAGFTV-YEDFLNYKSGIYKHIT-GETLGGHAIRIIGWGVE----NKAPYWLI 250 Query: 299 KNSWGEEWGMGGYVKMAKDRRNHCGIASAAS 329 NSW E+WG GY ++ + R+ C I S + Sbjct: 251 ANSWNEDWGENGYFRIVRG-RDECSIESEVT 280 >1CPJ-A nrPDB Length = 260 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 71/253 (28%), Positives = 108/253 (42%), Gaps = 45/253 (17%) Query: 113 EAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGR--LISLSEQNL 166 P S D RE+ P +++QG CGSCWAF A A+ ++ T + +S ++L Sbjct: 6 NLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDL 65 Query: 167 VDCSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVAND 222 + C G Q +GCNGG A+ + +GG+ + T C+++ + Sbjct: 66 LTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPC 125 Query: 223 TGFVDIPKQ----------------------------EKALMKAVATVGPISVAIDAGHE 254 TG D PK EK +M + GP+ A Sbjct: 126 TGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-FS 184 Query: 255 SFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 FL YK G+Y + + H + ++G+G E + YWLV NSW +WG G+ K+ Sbjct: 185 DFLTYKSGVY-KHEAGDVMGGHAIRILGWGIE----NGVPYWLVANSWNADWGDNGFFKI 239 Query: 315 AKDRRNHCGIASA 327 + NHCGI S Sbjct: 240 LRGE-NHCGIESE 251 >3CBK-A nrPDB Length = 266 Score = 215 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 68/253 (26%), Positives = 106/253 (41%), Gaps = 45/253 (17%) Query: 113 EAPRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGRLIS--LSEQNL 166 + P S D RE+ P +++QG CGS WAF A A+ ++ T +S +S ++L Sbjct: 6 KLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSAEDL 65 Query: 167 VDCSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCK---------- 212 + C G +GCNGG A+ + +GGL + C+ Sbjct: 66 LTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNGARPPC 125 Query: 213 ----------------YNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAGHE 254 Y+P Y G+ + EK +M + GP+ A + Sbjct: 126 TGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-YS 184 Query: 255 SFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 FL YK G+Y H + ++G+G E + YWLV NSW +WG G+ K+ Sbjct: 185 DFLLYKSGVYQHVT-GEMMGGHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFKI 239 Query: 315 AKDRRNHCGIASA 327 + ++HCGI S Sbjct: 240 LRG-QDHCGIESE 251 >4I04-A nrPDB Length = 323 Score = 214 bits (545), Expect = 5e-56, Method: Composition-based stats. Identities = 78/315 (24%), Positives = 124/315 (39%), Gaps = 54/315 (17%) Query: 56 MKMIELHNQEYREGKHSFTMAMNAFGDMTSE--EFRQVMNGFQNRKPRKGKVFQEPLFYE 113 + I H + S N F + + R+ R+ V E Sbjct: 17 ISYINEHPNAGWRAEKS-----NRFHSLDDARIQMGARREEPDLRRTRRPTVDHNDWNVE 71 Query: 114 APRSVDWREKGY----VTPVKNQGQCGSCWAFSATGALEGQMFRKTG--RLISLSEQNLV 167 P S D R+K + +++Q +CGS WAF A A+ + ++G + + LS +L+ Sbjct: 72 IPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAVDLL 131 Query: 168 DCSGPQGNEGCNGGLMDYAFQYVQDNGGLDS--------EESYPYEATE----------- 208 C G GC GG++ A+ Y G + E YP+ E Sbjct: 132 SCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCG 190 Query: 209 ----------ESC--KYNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAGHE 254 ++C KY Y+ G ++ EKA+ K + GP+ +E Sbjct: 191 SKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV-YE 249 Query: 255 SFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 FL YK GIY H + ++G+G E + YWL+ NSW E+WG GY ++ Sbjct: 250 DFLNYKSGIYKHIT-GETLGGHAIRIIGWGVE----NKAPYWLIANSWNEDWGENGYFRI 304 Query: 315 AKDRRNHCGIASAAS 329 + R+ C I S + Sbjct: 305 VRG-RDECSIESEVT 318 >5VPK-A nrPDB Length = 223 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 69/226 (30%), Positives = 97/226 (42%), Gaps = 15/226 (6%) Query: 112 YEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSG 171 P +D R VTP++ QG CGSCWAFS A E + LSEQ LVDC+ Sbjct: 9 VNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCAS 68 Query: 172 PQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY--NPKYSVANDTGFV--D 227 GC+G + +Y+Q N G+ E SYPY A E+ C+ + Y ++N D Sbjct: 69 ---QHGCHGDTIPRGIEYIQQN-GVVEERSYPYVAREQQCRRPNSQHYGISNYCQIYPPD 124 Query: 228 IPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 287 + + +AL + + I D +F Y + D + H V +VGYG Sbjct: 125 VKQIREALTQTHTAIAVIIGIKDL--RAFQHYDGRTIIQHDNGYQPNYHAVNIVGYG--- 179 Query: 288 TESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 + YW+V+NSW WG GY N I + Sbjct: 180 -STQGVDYWIVRNSWDTTWGDSGYGYFQAG-NNLMMIEQYPYVVIM 223 >5VCN-A nrPDB Length = 222 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 66/205 (32%), Positives = 97/205 (47%), Gaps = 12/205 (5%) Query: 110 LFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDC 169 + AP +D R+ VTP++ QG CGSCWAFS A E + + L+EQ LVDC Sbjct: 6 INGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDC 65 Query: 170 SGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI- 228 + GC+G + +Y+Q N G+ E Y Y A E+SC+ P + + I Sbjct: 66 AS---QHGCHGDTIPRGIEYIQHN-GVVQESYYRYVAREQSCR-RPNAQRFGISNYCQIY 120 Query: 229 PKQEKALMKAVAT-VGPISVAIDAGH-ESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFE 286 P + +A+A I+V I ++F Y + D + H V +VGY Sbjct: 121 PPNANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGY--- 177 Query: 287 STESDNNKYWLVKNSWGEEWGMGGY 311 + + YW+V+NSW WG GY Sbjct: 178 -SNAQGVDYWIVRNSWDTNWGDNGY 201 >5OGQ-A nrPDB Length = 254 Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats. Identities = 71/257 (27%), Positives = 111/257 (43%), Gaps = 47/257 (18%) Query: 112 YEAPRSVDWREKGY----VTPVKNQGQCGSCWAFSATGALEGQMFRKTG--RLISLSEQN 165 E P S D R+K + +++Q +CGSCWAF A A+ + ++G + + LS + Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 166 LVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLD--------SEESYPYEATE--------- 208 L+ C G GC GG++ A+ Y G + E YP+ E Sbjct: 61 LLSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPP 119 Query: 209 ------------ESC--KYNPKYSVANDTGF--VDIPKQEKALMKAVATVGPISVAIDAG 252 ++C KY Y+ G ++ EKA+ K + GP+ Sbjct: 120 CGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV- 178 Query: 253 HESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYV 312 +E FL YK GIY H + ++G+G E + YWL+ NSW E+WG GY Sbjct: 179 YEDFLNYKSGIYKHIT-GETLGGHAIRIIGWGVE----NKAPYWLIANSWNEDWGENGYF 233 Query: 313 KMAKDRRNHCGIASAAS 329 ++ + R+ C I S + Sbjct: 234 RIVRG-RDECSIESEVT 249 >4HWY-A nrPDB Length = 340 Score = 197 bits (501), Expect = 6e-51, Method: Composition-based stats. Identities = 70/258 (27%), Positives = 102/258 (39%), Gaps = 37/258 (14%) Query: 101 RKGKVFQEPLFYEAPRSVD----WREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTG 156 K + +E P S D W + + +Q CGSCWA +A A+ + G Sbjct: 81 PKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGG 140 Query: 157 -RLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGL-DSEESYPYEATE------ 208 + + +S +L+ C G +GCNGG D A+ Y G + D + YP+ Sbjct: 141 VQDVHISAGDLLACCSDCG-DGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSK 199 Query: 209 -------------ESCKY---NPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAIDA 251 C Y +P V N + + E M+ + GP VA D Sbjct: 200 NGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDV 259 Query: 252 GHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGY 311 +E F+ Y G+Y H V +VG+G S+ YW + NSW EWGM GY Sbjct: 260 -YEDFIAYNSGVYHHVS-GQYLGGHAVRLVGWGT----SNGVPYWKIANSWNTEWGMDGY 313 Query: 312 VKMAKDRRNHCGIASAAS 329 + + CGI S Sbjct: 314 FLIRRGSS-ECGIEDGGS 330 >2DCB-A nrPDB Length = 256 Score = 184 bits (468), Expect = 4e-47, Method: Composition-based stats. Identities = 67/252 (26%), Positives = 107/252 (42%), Gaps = 45/252 (17%) Query: 114 APRSVDWREKGYVTP----VKNQGQCGSCWAFSATGALEGQMFRKTGR--LISLSEQNLV 167 P S D RE+ P +++QG CGSCWAF A A+ ++ + + +S ++++ Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 168 DCSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYNPKYSVANDT 223 C G + +GCNGG A+ + +GGL + + C+++ S T Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 224 GFVDIP----------------------------KQEKALMKAVATVGPISVAIDAGHES 255 G D P EK +M + GP+ A + Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSV-YSD 179 Query: 256 FLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMA 315 FL YK G+Y H + ++G+G E + YWLV NSW +WG G+ K+ Sbjct: 180 FLLYKSGVYQHVS-GEIMGGHAIRILGWGVE----NGTPYWLVGNSWNTDWGDNGFFKIL 234 Query: 316 KDRRNHCGIASA 327 + ++HCGI S Sbjct: 235 RG-QDHCGIESE 245 >5I4H-A nrPDB Length = 106 Score = 184 bits (466), Expect = 7e-47, Method: Composition-based stats. Identities = 105/106 (99%), Positives = 105/106 (99%) Query: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172 EAPRSVDWREKGYVTPVKNQGQCGS WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS 218 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS 106 >5I4H-B nrPDB Length = 112 Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 111/112 (99%), Positives = 111/112 (99%) Query: 222 DTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVV 281 D GFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVV Sbjct: 1 DAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVV 60 Query: 282 GYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 GYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV Sbjct: 61 GYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >4CI7-A nrPDB Length = 470 Score = 179 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 60/245 (24%), Positives = 96/245 (39%), Gaps = 23/245 (9%) Query: 88 FRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGAL 147 F M G R + + P Y++ + + + G TP KNQG + W+FS L Sbjct: 42 FPHEMEGTTLRNKGRSSL---PSAYKSSVAYNPMDLGLTTPAKNQGSLNTAWSFSGMSTL 98 Query: 148 EGQMFRKTGRLISLSEQNLV--DCSGPQG--NEGCNGGLMDYAFQYVQDNGGLDSEESYP 203 E + K LSE++L G G + +G A Y+ G E+ P Sbjct: 99 EAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIP 158 Query: 204 YEATEE------SCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFL 257 Y E + + N T V + K ++ + A+ G SV H S Sbjct: 159 YNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNKDKETVKNAIMQYG--SVTSGYAHYSTY 216 Query: 258 FYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD--------NNKYWLVKNSWGEEWGMG 309 F K+ + ++H V +VG+ ++ + +N WLVK+SWGE M Sbjct: 217 FNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMK 276 Query: 310 GYVKM 314 G+ + Sbjct: 277 GFFWI 281 >3CH2-X nrPDB Length = 265 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 59/225 (26%), Positives = 92/225 (40%), Gaps = 33/225 (14%) Query: 129 VKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAF- 187 V++QG C + W F++ LE K +S + +C + + C+ G F Sbjct: 24 VEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDRCDEGSSPMEFL 83 Query: 188 QYVQDNGGLDSEESYPYEAT---EESCKYNPKYSVANDTGFVDIPKQE------------ 232 Q ++D G L +E +YPY E+ K + D G + K E Sbjct: 84 QIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGYTAY 143 Query: 233 -------------KALMKAVATVGPISVAIDAGHESFLFYK-EGIYFEPDCSSEDMDHGV 278 K + V G + I A E+ + Y+ G + C + DH V Sbjct: 144 ESERFHDNMDAFVKIIKTEVMNKGSVIAYIKA--ENVMGYEFSGKKVQNLCGDDTADHAV 201 Query: 279 LVVGYG-FESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHC 322 +VGYG + ++E + YW+V+NSWG WG GY K+ HC Sbjct: 202 NIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >4D59-A nrPDB Length = 406 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 54/219 (24%), Positives = 87/219 (39%), Gaps = 20/219 (9%) Query: 114 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLV--DCSG 171 + + + + G TP KNQG + W+FS LE + K LSE++L G Sbjct: 1 SSVAYNPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGG 60 Query: 172 PQG--NEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEE------SCKYNPKYSVANDT 223 G + +G A Y+ G E+ PY E + + N T Sbjct: 61 KYGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVT 120 Query: 224 GFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGY 283 V + K ++ + A+ G SV H S F K+ + ++H V +VG+ Sbjct: 121 DVVRLNKDKETVKNAIMQYG--SVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGW 178 Query: 284 GFESTESD--------NNKYWLVKNSWGEEWGMGGYVKM 314 ++ + +N WLVK+SWGE M G+ + Sbjct: 179 DDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 217 >1DEU-A nrPDB Length = 277 Score = 167 bits (422), Expect = 9e-42, Method: Composition-based stats. Identities = 74/242 (30%), Positives = 111/242 (45%), Gaps = 40/242 (16%) Query: 100 PRKGKVFQEPLFYEAPRSVDWREK---GYVTPVKNQG---QCGSCWAFSATGALEGQMFR 153 PR + + P+S DWR Y + +NQ CGSCWA ++T A+ ++ Sbjct: 25 PRPHEYLS---PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINI 81 Query: 154 K-TGRLIS--LSEQNLVDCSGPQGNEG-CNGGLMDYAFQYVQDNGGLDSEESYPYEATEE 209 K G S LS QN++DC GN G C GG + Y + G+ E Y+A ++ Sbjct: 82 KRKGAWPSTLLSVQNVIDC----GNAGSCEGGNDLSVWDYAHQH-GIPDETCNNYQAKDQ 136 Query: 210 SC-KYNP--------------KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHE 254 C K+N Y++ + + +EK +M + GPIS I A Sbjct: 137 ECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREK-MMAEIYANGPISCGIMATER 195 Query: 255 SFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 Y GIY E + ++H V V G+G SD +YW+V+NSWGE WG G++++ Sbjct: 196 -LANYTGGIYAEYQ-DTTYINHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRI 249 Query: 315 AK 316 Sbjct: 250 VT 251 >1EF7-A nrPDB Length = 242 Score = 161 bits (407), Expect = 5e-40, Method: Composition-based stats. Identities = 72/228 (31%), Positives = 107/228 (46%), Gaps = 37/228 (16%) Query: 114 APRSVDWREK---GYVTPVKNQG---QCGSCWAFSATGALEGQMFRK-TGRLIS--LSEQ 164 P+S DWR Y + +NQ CGSCWA ++T A+ ++ K G S LS Q Sbjct: 1 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 60 Query: 165 NLVDCSGPQGNEG-CNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC-KYNP------- 215 N++DC GN G C GG + Y + G+ E Y+A ++ C K+N Sbjct: 61 NVIDC----GNAGSCEGGNDLSVWDYAHQH-GIPDETCNNYQAKDQECDKFNQCGTCNEF 115 Query: 216 -------KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPD 268 Y++ + + +EK +M + GPIS I A Y GIY E Sbjct: 116 KECHAIRNYTLWRVGDYGSLSGREK-MMAEIYANGPISCGIMATER-LANYTGGIYAEYQ 173 Query: 269 CSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAK 316 + ++H V V G+G SD +YW+V+NSWGE WG G++++ Sbjct: 174 -DTTYINHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRIVT 216 >4OEL-A nrPDB Length = 370 Score = 160 bits (404), Expect = 1e-39, Method: Composition-based stats. Identities = 66/243 (27%), Positives = 111/243 (45%), Gaps = 26/243 (10%) Query: 41 GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKP 100 ++E + +++ + ++ N + + M + +T + + G + P Sbjct: 133 KNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYM---EYETLTLGDMIRRSGGHSRKIP 189 Query: 101 R------KGKVFQEPLFYEAPRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQM 151 R ++ Q+ L P S DWR +V+PV+NQ CGSC++F++ G LE ++ Sbjct: 190 RPKPAPLTAEIQQKIL--HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARI 247 Query: 152 FRKTG--RLISLSEQNLVDCSGPQGNEGCNGGLM-DYAFQYVQDNGGLDSEESYPYEATE 208 T + LS Q +V CS Q +GC GG A +Y QD GL E +PY T+ Sbjct: 248 RILTNNSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDF-GLVEEACFPYTGTD 304 Query: 209 ESCKYNPKYSVANDTGFVDI----PKQEKALMK-AVATVGPISVAIDAGHESFLFYKEGI 263 CK + + + +ALMK + GP++VA + ++ FL YK+GI Sbjct: 305 SPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGI 363 Query: 264 YFE 266 Y Sbjct: 364 YHH 366 >1CSB-B nrPDB Length = 205 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 50/201 (24%), Positives = 80/201 (39%), Gaps = 39/201 (19%) Query: 159 ISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCK-- 212 + +S ++L+ C G +GCNGG A+ + +GGL + C+ Sbjct: 3 VEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHH 62 Query: 213 ------------------------YNPKYSVANDTGF--VDIPKQEKALMKAVATVGPIS 246 Y+P Y G+ + EK +M + GP+ Sbjct: 63 VNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVE 122 Query: 247 VAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEW 306 A + FL YK G+Y H + ++G+G E + YWLV NSW +W Sbjct: 123 GAFSV-YSDFLLYKSGVYQHVT-GEMMGGHAIRILGWGVE----NGTPYWLVANSWNTDW 176 Query: 307 GMGGYVKMAKDRRNHCGIASA 327 G G+ K+ + ++HCGI S Sbjct: 177 GDNGFFKILRG-QDHCGIESE 196 >4CDF-B nrPDB Length = 166 Score = 153 bits (388), Expect = 7e-38, Method: Composition-based stats. Identities = 57/165 (34%), Positives = 83/165 (50%), Gaps = 15/165 (9%) Query: 113 EAPRSVDWREK---GYVTPVKNQGQCGSCWAFSATGALEGQMFRKTG--RLISLSEQNLV 167 P S DWR +V+PV+NQ CGSC++F++ G LE ++ T + LS Q +V Sbjct: 2 HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVV 61 Query: 168 DCSGPQGNEGCNGGLM-DYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFV 226 CS Q +GC GG A +Y QD GL E +PY T+ CK + + Sbjct: 62 SCS--QYAQGCEGGFPYLIAGKYAQDF-GLVEEACFPYTGTDSPCKMKEDCFRYYSSEYH 118 Query: 227 DI----PKQEKALMK-AVATVGPISVAIDAGHESFLFYKEGIYFE 266 + +ALMK + GP++VA + ++ FL YK+GIY Sbjct: 119 YVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHH 162 >5FPW-A nrPDB Length = 321 Score = 133 bits (334), Expect = 1e-31, Method: Composition-based stats. Identities = 61/279 (21%), Positives = 103/279 (36%), Gaps = 39/279 (13%) Query: 82 DMTSEEFRQVMNGFQNRKP--RKGKVFQEPLFYEAPRSVDWREKGYVTP----VKNQGQC 135 ++T E +++ + + + +E L E P S D EK P + +Q C Sbjct: 41 NITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTELPESFDSAEKWPNCPTIREIADQSAC 100 Query: 136 GSCWAFSATGALEGQMFRKTG-RLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNG 194 + WA S + + G + + +S +L+ C G GG +A++Y + G Sbjct: 101 RASWAVSTASVISDRYCTVGGVQQLRISAAHLLSCCKQCGGGC-KGGFPGFAWRYYVEYG 159 Query: 195 GLDS-EESYPYEATEE--------SC---KYNPKYSVANDTGF------------VDIPK 230 S + YP+ E C ++ A T + Sbjct: 160 IASSYCQPYPFPHCEHRGAQGNKTPCSKYNFDTPKCQATCTDKSIPLVKYRGSATYLLLH 219 Query: 231 QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTES 290 E+ + + GP VA+ + YK G+Y D V VVG+G + Sbjct: 220 GEEDYKRELYFNGPF-VAVFYVYTDLFAYKSGVYRHVD-GDFLGGTAVKVVGWG----KL 273 Query: 291 DNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAAS 329 + YW V N+W +WGM GY+ + + N C I Sbjct: 274 NGTPYWKVANTWDTDWGMDGYLLILRG-NNECNIEHLGF 311 >1SP4-B nrPDB Length = 205 Score = 125 bits (313), Expect = 4e-29, Method: Composition-based stats. Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 39/201 (19%) Query: 159 ISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQD----NGGLDSEESYPYEATEESCKYN 214 + +S ++++ C G + +GCNGG A+ + +GGL + + C+++ Sbjct: 4 VEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHH 63 Query: 215 PKYSVANDTGFVDIP----------------------------KQEKALMKAVATVGPIS 246 S TG D P EK +M + GP+ Sbjct: 64 VNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVE 123 Query: 247 VAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEW 306 A + FL YK G+Y H + ++G+G E + YWLV NSW +W Sbjct: 124 GAFSV-YSDFLLYKSGVYQHVS-GEIMGGHAIRILGWGVE----NGTPYWLVGNSWNTDW 177 Query: 307 GMGGYVKMAKDRRNHCGIASA 327 G G+ K+ + ++HCGI S Sbjct: 178 GDNGFFKILRG-QDHCGIESE 197 >4OEM-B nrPDB Length = 70 Score = 90.8 bits (224), Expect = 8e-19, Method: Composition-based stats. Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 3/67 (4%) Query: 266 EPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIA 325 +P E +H VL+VGYG +S + YW+VKNSWG WG GY ++ + + C I Sbjct: 1 DPFNPFELTNHAVLLVGYGTDS--ASGMDYWIVKNSWGTGWGENGYFRIRRG-TDECAIE 57 Query: 326 SAASYPT 332 S A T Sbjct: 58 SIAVAAT 64 >2L95-A nrPDB Length = 80 Score = 90.4 bits (223), Expect = 9e-19, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 40/69 (57%) Query: 26 EAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTS 85 + +W ++K+ ++ Y E+ RR ++ ++ IE HN+++ +G+ ++ M +N D+T Sbjct: 7 DEEWVEYKSKFDKNYEAEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADLTP 66 Query: 86 EEFRQVMNG 94 EEF Q Sbjct: 67 EEFAQRSGK 75 >3OIS-A nrPDB Length = 291 Score = 60.0 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 45/238 (18%), Positives = 79/238 (33%), Gaps = 48/238 (20%) Query: 107 QEPLFYEAPRSVDWREKGYVTP---VKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSE 163 ++ + P VD +TP V +QG+ GSC A + A++ + Sbjct: 50 EKSVIAALPPKVD------LTPPFQVYDQGRIGSCTANALAAAIQ-FERIHDKQSPEFIP 102 Query: 164 QNLVDCSGPQGNEGCNGGLMDYAFQYVQDNG-------GLDSEESYPY------------ 204 L NE G ++Y + +G G+ E+ +PY Sbjct: 103 SRL----FIYYNERKIEGHVNYDSGAMIRDGIKVLHKLGVCPEKEWPYGDTPADPRTEEF 158 Query: 205 -----EATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFY 259 + + S + T + + + L +A P + S++ Sbjct: 159 PPGAPASKKPSDQCYKDAQNYKITEYSRVAQDIDHLKACLAVGSPFVFGFSV-YNSWVGN 217 Query: 260 KE---GIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 I + + H VL VGY D +++ ++NSWG G GY M Sbjct: 218 NSLPVRIPLPTKNDTLEGGHAVLCVGY------DDEIRHFRIRNSWGNNVGEDGYFWM 269 >5WDK-A nrPDB Length = 401 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 36/92 (39%), Gaps = 10/92 (10%) Query: 122 EKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQ------NLVDCSGPQGN 175 ++ +T VKNQ + G+CW +S+ LE ++ R LSE L Sbjct: 36 KENPITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSEMFTVYNTYLDRADAAVRT 95 Query: 176 EG----CNGGLMDYAFQYVQDNGGLDSEESYP 203 G GG A ++ G + EE P Sbjct: 96 HGDVSFSQGGSFYDALYGMETFGLVPEEEMRP 127 Score = 36.1 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 21/31 (67%), Gaps = 3/31 (9%) Query: 275 DHGVLVVGYGFESTESDNNKYWLVKNSWGEE 305 DHG+ + YG + + + N+Y++VKNSWG Sbjct: 335 DHGMQI--YGI-AKDQEGNEYYMVKNSWGTN 362 >4K7C-A nrPDB Length = 446 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 3/45 (6%) Query: 268 DCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYV 312 D M H +++ G + W V+NSWGE+ G GY Sbjct: 356 DYGESLMTHAMVLTGVDLVDGKPTK---WKVENSWGEKVGEKGYF 397 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 14/30 (46%), Gaps = 4/30 (13%) Query: 129 VKNQGQCGSCWAFSATGAL----EGQMFRK 154 V NQ Q G CW F+A + + Q K Sbjct: 61 VSNQKQSGRCWMFAALNTMRHGIQAQFKIK 90 >2CB5-A nrPDB Length = 453 Score = 37.3 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 19/45 (42%) Query: 270 SSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKM 314 M H + + + W V+NSWGE+ G GY+ M Sbjct: 365 GESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCM 409 >1A6R-A nrPDB Length = 471 Score = 36.1 bits (82), Expect = 0.022, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 57/180 (31%), Gaps = 45/180 (25%) Query: 187 FQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTG---------------------- 224 ++YV + + + +S P E + K +P V+ Sbjct: 254 WEYVDKDKKIHTIKSTPLEFASKYAKLDPSTPVSLINDPRHPYGKLIKIDRLGNVLGGDA 313 Query: 225 FVDIPKQEKALMKAVAT--VGPISVAIDAGHESFLFYKEGIYF-----EPDCSS------ 271 + + + L K V +V + F+ K G+ P Sbjct: 314 VIYLNVDNETLSKLVVKRLQNNKAVFFGSHTPKFMDKKTGVMDIELWNYPAIGYNLPQQK 373 Query: 272 --------EDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGG-YVKMAKDRRNHC 322 M H +L+ G + T +Y V+NSWG++ G G YV K +C Sbjct: 374 ASRIRYHESLMTHAMLITGCHVDETSKLPLRY-RVENSWGKDSGKDGLYVMTQKYFEEYC 432 Score = 30.7 bits (68), Expect = 0.99, Method: Composition-based stats. Identities = 18/40 (45%), Positives = 19/40 (47%), Gaps = 9/40 (22%) Query: 127 TPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNL 166 TPV NQ G W F+AT L RL LSE NL Sbjct: 79 TPVTNQKSSGRAWLFAATNQL---------RLNVLSELNL 109 >5DMY-A nrPDB Length = 904 Score = 33.0 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 39/135 (28%), Gaps = 14/135 (10%) Query: 180 GGLMDYAFQY--VQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMK 237 G Y + D G + Y Y+ +++ T + E + K Sbjct: 618 GSWPSPKNSYFGIVDTAGFPKDTYYFYQ---------SQWNDDVHTLHILPAWNENVVAK 668 Query: 238 AVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWL 297 P+ V DA F +G + + GY ++ E + Sbjct: 669 GSGNKVPVVVYTDAAKVKLYFTPKGSTEKRLIGEKSFTKKTTAAGYTYQVYEGTDKDSTA 728 Query: 298 VKN---SWGEEWGMG 309 KN +W W G Sbjct: 729 HKNMYLTWNVPWAEG 743 >2XGT-A nrPDB Length = 435 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 37 NRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMA 76 N + E + R ++ +K ++ HN E G +FT Sbjct: 265 NPKFQPPERPFLRMEYKDAIKWLQEHNVENEFGN-TFTYG 303 >2QGM-A nrPDB Length = 445 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 6/74 (8%) Query: 139 WAFSATGALE---GQMFRKTGRLI-SLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNG 194 WA + A+E + I L EQ L D E G M +A G Sbjct: 255 WAKATASAIEKFTTMLLPNDYPSIIKLHEQYLAD-HAMWAQETFGGKTMVWAHNIHIAKG 313 Query: 195 GLDSEESYPYEATE 208 +D E+ YPY A + Sbjct: 314 IID-EKLYPYVAGQ 326 >2Z51-A nrPDB Length = 154 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 10/15 (66%), Positives = 10/15 (66%) Query: 124 GYVTPVKNQGQCGSC 138 G V VK QG CGSC Sbjct: 34 GNVVRVKLQGACGSC 48 >5ZRD-A nrPDB Length = 549 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 180 GGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAV 239 GG FQY + L ++ YPY C + +V K E+AL V Sbjct: 54 GGYHGEPFQYRKPVDALPQDDIYPYWG--GYCNHGNVLFPTWHRMYVY--KLEEALQSIV 109 >1L9N-A nrPDB Length = 692 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 19/38 (50%), Gaps = 13/38 (34%) Query: 115 PRSVD--------WREKGYVTPVKNQGQCGSCWAFSAT 144 PRS D W++ G ++PV+ G CW F+ T Sbjct: 246 PRSWDGSVEILKNWKKSG-LSPVRY----GQCWVFAGT 278 >2OK5-A nrPDB Length = 752 Score = 28.8 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 28/99 (28%), Gaps = 14/99 (14%) Query: 185 YAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMK------- 237 A +YV +G YPY +C+ +S + K E + Sbjct: 41 QALEYVCPSGF------YPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDF 94 Query: 238 AVATVGPISVAIDAGHE-SFLFYKEGIYFEPDCSSEDMD 275 P S + E SF Y + ++ Sbjct: 95 ENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVN 133 >1IYW-A nrPDB Length = 862 Score = 28.4 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 27/83 (32%), Gaps = 4/83 (4%) Query: 38 RLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN 97 + + R E+ + E + + A D + E F + Sbjct: 97 KEGKTRHDLGREKFLERVWQWKEESGGTILKQL----KRLGASADWSREAFTMDEKRSRA 152 Query: 98 RKPRKGKVFQEPLFYEAPRSVDW 120 + + + E L Y APR V+W Sbjct: 153 VRYAFSRYYHEGLAYRAPRLVNW 175 >1V9N-A nrPDB Length = 360 Score = 28.4 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 22/59 (37%), Gaps = 7/59 (11%) Query: 280 VVGY-----GFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 VVGY + + + +NS +G+ GY + GI+ S P V Sbjct: 99 VVGYRSMKLAIKKAKDTGIGIVIARNS--NHYGIAGYYALMAAEEGMIGISMTNSRPLV 155 >2UXY-A nrPDB Length = 341 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 26/67 (38%), Gaps = 5/67 (7%) Query: 196 LDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMK---AVATVGPISVAIDAG 252 + + +YP + C + G++ K ++ +M A A ++VA AG Sbjct: 165 ICDDGNYPEIWRD--CAMKGAELIVRCQGYMYPAKDQQVMMAKAMAWANNCYVAVANAAG 222 Query: 253 HESFLFY 259 + Y Sbjct: 223 FDGVYSY 229 >4MHI-A nrPDB Length = 334 Score = 28.0 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 23/68 (33%), Gaps = 7/68 (10%) Query: 143 ATGALEGQM-FRKTGRLISLS---EQNLVDCSGPQGNEG---CNGGLMDYAFQYVQDNGG 195 + + G+L L+ L DCS G C+ + + Y+ + Sbjct: 29 TVTHAQDILEKTHNGKLCDLNGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKAS 88 Query: 196 LDSEESYP 203 ++ YP Sbjct: 89 PANDLCYP 96 >2MAR-A nrPDB Length = 134 Score = 27.6 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 20/123 (16%), Positives = 41/123 (33%), Gaps = 10/123 (8%) Query: 3 PTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELH 62 P ++ AF + D +E W Y E +++ + K ++ + H Sbjct: 14 PQDVVKAFFELLKKDETKTDPEIEKDLDAWVDTLGGDYKAKFETFKKEMKAKEAELAKAH 73 Query: 63 NQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSV-DWR 121 + + A + ++ N + K+ ++ P+SV D Sbjct: 74 EEAVAKMTPEAKKADAELSKIAEDD-------SLNGIQKAQKIQA--IYKTLPQSVKDEL 124 Query: 122 EKG 124 EKG Sbjct: 125 EKG 127 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.142 0.466 Lambda K H 0.267 0.0434 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,645,321 Number of Sequences: 36641 Number of extensions: 617696 Number of successful extensions: 2256 Number of sequences better than 10.0: 98 Number of HSP's better than 10.0 without gapping: 172 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1427 Number of HSP's gapped (non-prelim): 216 length of query: 333 length of database: 10,336,785 effective HSP length: 98 effective length of query: 235 effective length of database: 6,745,967 effective search space: 1585302245 effective search space used: 1585302245 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.3 bits)