BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07451 (260 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1Z93-A nrPDB 538 e-154 1FLJ-A nrPDB 500 e-142 3D0N-A nrPDB 314 2e-86 4QK3-A nrPDB 313 6e-86 4CNR-A nrPDB 305 1e-83 6FAF-A nrPDB 303 5e-83 6G4T-A nrPDB 283 7e-77 1URT-A nrPDB 240 5e-64 2W2J-A nrPDB 180 6e-46 1RJ5-A nrPDB 166 1e-41 4ETQ-X nrPDB 157 4e-39 6B9J-X nrPDB 157 4e-39 4LU3-A nrPDB 153 9e-38 3FE4-A nrPDB 152 2e-37 5LL9-A nrPDB 150 5e-37 5DVX-A nrPDB 139 2e-33 4X5S-A nrPDB 136 1e-32 4COQ-A nrPDB 132 1e-31 5JN8-A nrPDB 122 1e-28 3ZNC-A nrPDB 117 3e-27 4G7A-A nrPDB 117 6e-27 4XZ5-A nrPDB 111 3e-25 6EKI-A nrPDB 107 4e-24 5HPJ-A nrPDB 105 2e-23 1KOQ-A nrPDB 92 2e-19 4XIW-A nrPDB 86 2e-17 4TWL-A nrPDB 83 1e-16 1Y7W-A nrPDB 70 1e-12 5TT3-A nrPDB 69 2e-12 3B1B-A nrPDB 64 9e-11 3Q31-A nrPDB 60 1e-09 5HJK-A nrPDB 32 0.39 5KHR-J nrPDB 30 0.99 6G13-A nrPDB 29 2.2 6DQP-A nrPDB 28 4.0 >1Z93-A nrPDB Length = 266 Score = 538 bits (1387), Expect = e-154, Method: Compositional matrix adjust. Identities = 257/260 (98%), Positives = 258/260 (99%) Query: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 MAKEWGYASHNGPDHWHELFPNAKGENQSP+ELHTKDIRHDPSLQPWSVSYDGGSAKTIL Sbjct: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL Sbjct: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP Sbjct: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 S LFPA RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL Sbjct: 181 SSLFPASRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 Query: 241 VSNWRPPQPINNRVVRASFK 260 VSNWRPPQPINNRVVRASFK Sbjct: 241 VSNWRPPQPINNRVVRASFK 260 >1FLJ-A nrPDB Length = 260 Score = 500 bits (1287), Expect = e-142, Method: Compositional matrix adjust. Identities = 237/259 (91%), Positives = 244/259 (94%) Query: 2 AKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILN 61 AKEWGYASHNGP+HWHEL+P AKG+NQSP+ELHTKDIRHDPSLQPWSVSYD GSAKTILN Sbjct: 2 AKEWGYASHNGPEHWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVSYDPGSAKTILN 61 Query: 62 NGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLV 121 NGKTCRVVFDDT+DRSMLRGGPL GPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLV Sbjct: 62 NGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLV 121 Query: 122 HWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPS 181 HWNPKYNTF EALKQ DGIAV+GIFLKIG E GEFQI LDALDKIKTKGKEAPF FDPS Sbjct: 122 HWNPKYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFNHFDPS 181 Query: 182 CLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLV 241 CLFPACRDYWTY GSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSL +SAENEPPVPLV Sbjct: 182 CLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLV 241 Query: 242 SNWRPPQPINNRVVRASFK 260 NWRPPQPI RVVRASFK Sbjct: 242 GNWRPPQPIKGRVVRASFK 260 >3D0N-A nrPDB Length = 264 Score = 314 bits (805), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 150/256 (58%), Positives = 183/256 (71%), Gaps = 1/256 (0%) Query: 5 WGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGK 64 WGY HNGP HW E FP A G+ QSP+E+ TK++++D SL+P S+ YD SAK I N+G Sbjct: 8 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGH 67 Query: 65 TCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN 124 + V FDDT ++S+LRGGPL G YRLRQ HLHWGS+DDHGSEH VDGV YAAELH+VHWN Sbjct: 68 SFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWN 127 Query: 125 P-KYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCL 183 KY +F EA + DG+AV+G+FL+IG N + Q D LD IK KGK+ FT FD L Sbjct: 128 SDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSL 187 Query: 184 FPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSN 243 P DYWTY GS T PP E + W++LK+P+ +SS Q+AK RSLL +AE E LVSN Sbjct: 188 LPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSN 247 Query: 244 WRPPQPINNRVVRASF 259 RPPQP+ R VRASF Sbjct: 248 HRPPQPLKGRKVRASF 263 >4QK3-A nrPDB Length = 249 Score = 313 bits (801), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 149/260 (57%), Positives = 182/260 (70%), Gaps = 11/260 (4%) Query: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 M+ WGY HNGP+HWH+ FP AKGE QSPV++ T ++DPSL+P SVSYD ++ IL Sbjct: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 NNG V FDD+ D+++L+GGPL G YRL QFH HWGS D GSEHTVD KYAAELHL Sbjct: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 VHWN KY F +A++Q DG+AV+GIFLK+G Q +D LD IKTKGK A FT FDP Sbjct: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 L P DYWTY GS TTPP EC+ W++LKEP++VSS+Q+ K R L + Sbjct: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL-----------M 229 Query: 241 VSNWRPPQPINNRVVRASFK 260 V NWRP QP+ NR ++ASFK Sbjct: 230 VDNWRPAQPLKNRQIKASFK 249 >4CNR-A nrPDB Length = 262 Score = 305 bits (780), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 140/257 (54%), Positives = 180/257 (70%) Query: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 M+ WGY HNGP+HWH+ FP A GE QSPV++ T + DP+L+P ++ Y +++ ++ Sbjct: 3 MSHHWGYDKHNGPEHWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGEATSRRMV 62 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 N+G + V +DD+ D+++L+ GPL G YRL QFH HWGSSDD GSEHTVD KYAAELHL Sbjct: 63 NDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL 122 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 VHWN KY F A ++ DG+AV+G+FLK+G N Q LDALD IKTKGK F FDP Sbjct: 123 VHWNTKYGDFGTAAQEPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP 182 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 L P DYWTY GS TTPP E + W++LKEP++VSS QM K R+L +AE EP + Sbjct: 183 GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPEELM 242 Query: 241 VSNWRPPQPINNRVVRA 257 ++NWRP QP+ NR VR Sbjct: 243 LANWRPAQPLKNRQVRG 259 >6FAF-A nrPDB Length = 261 Score = 303 bits (776), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 140/257 (54%), Positives = 184/257 (71%), Gaps = 1/257 (0%) Query: 4 EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNG 63 +WGY NGP+ W +L+P A G NQSPV++ T + +HD SL+P SVSY+ +AK I+N G Sbjct: 5 DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVG 64 Query: 64 KTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHW 123 + V F+D +RS+L+GGP YRL QFH HWGS+++HGSEHTVDGVKY+AELH+ HW Sbjct: 65 HSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHW 124 Query: 124 N-PKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSC 182 N KY++ EA + DG+AVIG+ +K+G N + Q LDAL IKTKGK APFT FDPS Sbjct: 125 NSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPST 184 Query: 183 LFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVS 242 L P+ D+WTY GS T PP E + W++ KE ++VSS+Q+A+ RSLLS+ E + VP+ Sbjct: 185 LLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQH 244 Query: 243 NWRPPQPINNRVVRASF 259 N RP QP+ R VRASF Sbjct: 245 NNRPTQPLKGRTVRASF 261 >6G4T-A nrPDB Length = 274 Score = 283 bits (723), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 128/257 (49%), Positives = 180/257 (70%), Gaps = 1/257 (0%) Query: 5 WGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGK 64 WGY +GP HWH+L+P A+G+ QSP+ + + + PSLQP +SY+ + +I NNG Sbjct: 9 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 68 Query: 65 TCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN 124 + +V F+D+ DR+++ GGPL GPYRL+QFH HWG D GSEHTVDG + +ELHLVHWN Sbjct: 69 SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 128 Query: 125 P-KYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCL 183 KY+TF EA DG+AV+G+FL+ G E+ DAL ++ KG +A F+ F+P L Sbjct: 129 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKSL 188 Query: 184 FPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSN 243 PA R YWTY GS TTPP E + W++L+EP+++S QM K RSLL ++E++ + +V+N Sbjct: 189 LPASRHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDDERIHMVNN 248 Query: 244 WRPPQPINNRVVRASFK 260 +RPPQP+ RVV+ASF+ Sbjct: 249 FRPPQPLKGRVVKASFR 265 >1URT-A nrPDB Length = 248 Score = 240 bits (612), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 114/240 (47%), Positives = 156/240 (65%), Gaps = 1/240 (0%) Query: 22 NAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRG 81 +A+G QSP+ + KD +DP L P VSYD S + + N G +V FDD+ + S + G Sbjct: 1 SAEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGISG 60 Query: 82 GPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNP-KYNTFKEALKQRDGI 140 GPL YRL+QFH HWG++D+ GSEH VDG Y AELHLVHWN KY +K+A +G+ Sbjct: 61 GPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGL 120 Query: 141 AVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTP 200 AVIG+FLK+G + Q +D L +++ K + FDPSCL PACRDYWTY GS TTP Sbjct: 121 AVIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRDYWTYPGSLTTP 180 Query: 201 PCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK 260 P E + W++ K P+ VS Q++ R+LL S E +V+N+RP QP+ +R +R+SF+ Sbjct: 181 PLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFR 240 >2W2J-A nrPDB Length = 291 Score = 180 bits (456), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 96/257 (37%), Positives = 148/257 (57%), Gaps = 15/257 (5%) Query: 16 WHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS--YDGGSAKTILNNGKTCRVVFDDT 73 W +FP+A GE QSP+ L++++ R+DPSL +S Y + N+G T +V+ Sbjct: 38 WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKS- 96 Query: 74 YDRSMLRGGPLPG--PYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPK-YNTF 130 +S+L GGPLP + L + HWG + GSEHTV+ + ELHL+HWN + + Sbjct: 97 --KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSI 154 Query: 131 KEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFP--ACR 188 EA+ + GIA+I +F++IG E+ + + L I+ KGK F+P+ L P R Sbjct: 155 DEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLR 214 Query: 189 DYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVP-----LVSN 243 DYW Y+GS T PPC E + W+L + P+T+S Q+ + R L + + V L N Sbjct: 215 DYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDN 274 Query: 244 WRPPQPINNRVVRASFK 260 +RP QP+++RV+RA+F+ Sbjct: 275 FRPTQPLSDRVIRAAFQ 291 >1RJ5-A nrPDB Length = 261 Score = 166 bits (419), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 95/262 (36%), Positives = 137/262 (52%), Gaps = 12/262 (4%) Query: 5 WGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSL---QPWSVSYDGGSAKTILN 61 W Y +G DHW +P G+ QSP+ + T + DP L QP G + N Sbjct: 5 WTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPLDLHN 64 Query: 62 NGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDD-HGSEHTVDGVKYAAELHL 120 NG T ++ T L G LP Y Q HLHWG GSEH ++ AAELH+ Sbjct: 65 NGHTVQLSLPPT-----LHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAAELHV 119 Query: 121 VHWNPK-YNTFKEALKQRDGIAVIGIFLKIGH-ENGEFQIFLDALDKIKTKGKEAPFTKF 178 VH++ + Y++ EA ++ G+AV+GI +++G EN + L L +I+ K ++ F Sbjct: 120 VHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTSVPPF 179 Query: 179 DPSCLFPA-CRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPP 237 LFP ++ Y GS TTPPC + ++W + +S Q+ KL+ LSS E +P Sbjct: 180 SVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEEDPS 239 Query: 238 VPLVSNWRPPQPINNRVVRASF 259 PLV N+R PQP+N R + ASF Sbjct: 240 EPLVQNYRVPQPLNQRTIFASF 261 >4ETQ-X nrPDB Length = 269 Score = 157 bits (398), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 86/228 (37%), Positives = 130/228 (57%), Gaps = 10/228 (4%) Query: 29 SPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPY 88 SP+ + TK + L+P + Y+ TI N GK R+ F Y + GG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGGY----ISGGFLPNEY 61 Query: 89 RLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN-PKYNTFKEALKQRDGIAVIGIFL 147 L H++WG DD+GS H +D KY+ E++LVHWN KY++++EA K DG+ +I IFL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 148 KI-GHENGEFQIFLDALDKIKTKGKEAPF-TKFDPSCLFPACRDYWTYQGSFTTPPCEEC 205 ++ H+N FQ ++ LD I++ APF + F L P+ DY+TY G TT Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 206 IVWLLLKEPMTVSSDQMAKLRSLLSSAENE-PPVPLVSNWRPPQPINN 252 VW++ P+ + SDQ++K R+LLS + +E P + N+R P +N+ Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >6B9J-X nrPDB Length = 241 Score = 157 bits (398), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 86/228 (37%), Positives = 130/228 (57%), Gaps = 10/228 (4%) Query: 29 SPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPY 88 SP+ + TK + L+P + Y+ TI N GK R+ F Y + GG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGGY----ISGGFLPNEY 61 Query: 89 RLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN-PKYNTFKEALKQRDGIAVIGIFL 147 L H++WG DD+GS H +D KY+ E++LVHWN KY++++EA K DG+ +I IFL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 148 KI-GHENGEFQIFLDALDKIKTKGKEAPF-TKFDPSCLFPACRDYWTYQGSFTTPPCEEC 205 ++ H+N FQ ++ LD I++ APF + F L P+ DY+TY G TT Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 206 IVWLLLKEPMTVSSDQMAKLRSLLSSAENE-PPVPLVSNWRPPQPINN 252 VW++ P+ + SDQ++K R+LLS + +E P + N+R P +N+ Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >4LU3-A nrPDB Length = 279 Score = 153 bits (386), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 90/265 (33%), Positives = 136/265 (51%), Gaps = 12/265 (4%) Query: 2 AKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDP---SLQPWSVSYDGGSAKT 58 + W Y +G DHW +P QSP+++ T + DP +LQP G Sbjct: 4 GQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLD 63 Query: 59 ILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDD-HGSEHTVDGVKYAAE 117 + NNG T ++ T L G LP Y Q HLHWG GSEH ++ AE Sbjct: 64 LHNNGHTVQLSLPST-----LYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAE 118 Query: 118 LHLVHWNP-KYNTFKEALKQRDGIAVIGIFLKIGH-ENGEFQIFLDALDKIKTKGKEAPF 175 LH+VH++ Y++ EA ++ G+AV+GI +++G +N ++ L L +++ K ++ Sbjct: 119 LHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSV 178 Query: 176 TKFDPSCLFP-ACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAEN 234 F+ L P Y+ Y GS TTPPC + ++W + +S +Q+ KL+ L S E Sbjct: 179 PPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEE 238 Query: 235 EPPVPLVSNWRPPQPINNRVVRASF 259 EP LV N+R QP+N R+V ASF Sbjct: 239 EPSKLLVQNYRALQPLNQRMVFASF 263 >3FE4-A nrPDB Length = 278 Score = 152 bits (383), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 85/252 (33%), Positives = 143/252 (56%), Gaps = 14/252 (5%) Query: 15 HWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAKT-ILNNGKTCRVVFDD 72 HW + +P G+ QSP+ L +R++PSL+ +++ Y+ + + ++NNG T ++ Sbjct: 15 HWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPS 74 Query: 73 TYDRSMLRGGPLPGPYRLRQFHLHWG--SSDDHGSEHTVDGVKYAAELHLVHWNPKYNTF 130 T ++ G Y +Q H HWG SS+ GSEHTVDG+++ E+H+VH+N KY ++ Sbjct: 75 TMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSY 130 Query: 131 KEALKQRDGIAVIGIFLKIGH--ENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPA-C 187 A DG+AV+ F+++ + EN + F+ L IK G+ T D + P Sbjct: 131 DIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNL 190 Query: 188 RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPP 247 + Y+TY GS TTPPC E + W +L + + +S Q+ KL + L N+ + +++R Sbjct: 191 QHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK---TIHNDYRRT 247 Query: 248 QPINNRVVRASF 259 QP+N+RVV ++F Sbjct: 248 QPLNHRVVESNF 259 >5LL9-A nrPDB Length = 263 Score = 150 bits (379), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 87/264 (32%), Positives = 141/264 (53%), Gaps = 13/264 (4%) Query: 4 EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAKTIL-- 60 +W Y +G + W + +P+ G QSP++LH+ +++D SL P Y+ + K L Sbjct: 3 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLT 62 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDD-HGSEHTVDGVKYAAELH 119 NNG + ++ S + L Y Q HLHWG+ +D HGSEHTV G +AAELH Sbjct: 63 NNGHSVKLNLP-----SDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELH 117 Query: 120 LVHWNPK-YNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKF 178 +VH+N Y A + +G+AV+ + +++G N + L +K KG+EA F Sbjct: 118 IVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGF 177 Query: 179 DPSCLFPA-CRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPP 237 + L P +Y+ Y+GS TTPPC ++W + + P+ +S +Q+ L + L + P Sbjct: 178 NIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDP 237 Query: 238 VP--LVSNWRPPQPINNRVVRASF 259 P +++N+R Q + R+V SF Sbjct: 238 SPREMINNFRQVQKFDERLVYTSF 261 >5DVX-A nrPDB Length = 260 Score = 139 bits (349), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 84/258 (32%), Positives = 132/258 (51%), Gaps = 18/258 (6%) Query: 10 HNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS---YDGGSAKTILNNGKTC 66 + G W + P G QSPV++ + P+L+P +S + NNG + Sbjct: 4 YGGDPPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLRNNGHSV 63 Query: 67 RVVFDDTYDRSMLRGGPLPGP---YRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHW 123 ++ + + GP YR Q HLHWG++ GSEHTV+G ++ AE+H+VH Sbjct: 64 QLTLPPGLEMKL-------GPGREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHL 116 Query: 124 NPKYNTFKEALKQRDGIAVIGIFLKIG-HENGEFQIFLDALDKIKTKGKEAPFTKFDPSC 182 + KY EAL + G+AV+ FL+ G EN ++ L L++I +G E D S Sbjct: 117 STKYARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISA 176 Query: 183 LFPA-CRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLV 241 L P+ Y+ Y+GS TTPPC + ++W + + +++S+ Q+ L L + L Sbjct: 177 LLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWGPGDS---RLQ 233 Query: 242 SNWRPPQPINNRVVRASF 259 N+R QP+N RV+ ASF Sbjct: 234 LNFRATQPLNGRVIEASF 251 >4X5S-A nrPDB Length = 232 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 90/260 (34%), Positives = 136/260 (52%), Gaps = 44/260 (16%) Query: 5 WGYASHNGPDHWHELFPN---AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILN 61 W Y NGP++W +L P +NQSPV++ + + + L+ ++Y+ I+N Sbjct: 10 WSYEGENGPENWAKLNPEYFWCNLKNQSPVDI-SDNYKVHAKLEKLHINYNKAVNPEIVN 68 Query: 62 NGKTCRV-VFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 NG T +V V +D + ++G Y L+QFH H S EHTV+G Y E+HL Sbjct: 69 NGHTIQVNVLEDF--KLNIKGKE----YHLKQFHFHAPS------EHTVNGKYYPLEMHL 116 Query: 121 VHWNPKYNTFKEALKQRDG-IAVIGIFLKIGHENGEF-QIFLDALDKIKTKGKEAPFTKF 178 VH K +DG IAVIG+F K G N E ++F +AL K +G + Sbjct: 117 VH------------KDKDGNIAVIGVFFKEGKANPELDKVFKNAL---KEEGSKVFDGSI 161 Query: 179 DPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPV 238 + + L P ++Y+TY GS TTPPC E ++W++LK+P+T S Q+ +S++ N Sbjct: 162 NINALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIMKHNNN---- 217 Query: 239 PLVSNWRPPQPINNRVVRAS 258 RP QPIN+R + S Sbjct: 218 ------RPTQPINSRYILES 231 >4COQ-A nrPDB Length = 247 Score = 132 bits (332), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 91/258 (35%), Positives = 127/258 (49%), Gaps = 45/258 (17%) Query: 5 WGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 WGY+ GP+HW +L P G+NQSP+++++ D L P SV Y AK ++ Sbjct: 26 WGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAV-KACLAPVSVYYVS-DAKYVV 83 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYR--LRQFHLHWGSSDDHGSEHTVDGVKYAAEL 118 NNG T +VV RG + R L+QFH H SEHTV+G Y E Sbjct: 84 NNGHTIKVVMGG-------RGYVVVDGKRFYLKQFHFH------APSEHTVNGKHYPFEA 130 Query: 119 HLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFT-K 177 H VH L + I V+G+F K+G EN E + + + G++ T + Sbjct: 131 HFVH-----------LDKNGNITVLGVFFKVGKENPELEKVWRVMPE--EPGQKRHLTAR 177 Query: 178 FDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPP 237 DP L P RDY+ Y GS TTPPC E + W++ KEP+ +S +Q+ K R ++ N Sbjct: 178 IDPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGFDNN--- 234 Query: 238 VPLVSNWRPPQPINNRVV 255 RP QP+N R V Sbjct: 235 -------RPVQPLNARKV 245 >5JN8-A nrPDB Length = 266 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 78/244 (31%), Positives = 120/244 (49%), Gaps = 11/244 (4%) Query: 22 NAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAKTILNNGKTCRVVFDDTYDRSMLR 80 N + + QSP+ + T + D L + S YD T+ NNG + ++ ++ ++ + Sbjct: 27 NCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLEN---KASIS 83 Query: 81 GGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNT--FKEALKQRD 138 GG LP PY+ +Q HLHW GSEH++DG +A E+H+VH K + KEA D Sbjct: 84 GGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPED 143 Query: 139 GIAVIGIFLKIGHENGE-FQIFLDALDKIKTKGKEAPFTKFDPSCLFP---ACRDYWTYQ 194 IAV+ ++ G + E FQ ++AL I + L P R Y+ Y Sbjct: 144 EIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYL 203 Query: 195 GSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRV 254 GS TTP C+E +VW + +EP+ + +Q+ L + E V + N RP Q + R Sbjct: 204 GSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL-YYDKEQTVSMKDNVRPLQQLGQRT 262 Query: 255 VRAS 258 V S Sbjct: 263 VIKS 266 >3ZNC-A nrPDB Length = 258 Score = 117 bits (294), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 18/253 (7%) Query: 12 GPDHWHELFPNAKGENQ-SPVELHTKDIRHDPSLQPWS-VSYDGGSAKTILNNGKTCRVV 69 GP+ W P A ENQ SP+ + T + +P L P+ V YD I NN T + Sbjct: 16 GPEKW----PGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMT 71 Query: 70 FDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNT 129 + + GG LP Y Q HLHW + +D+GSEH++DG +A E+H+VH K + Sbjct: 72 LGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH--KKLTS 126 Query: 130 FKEALKQRDGIAVIGIFLKIGHE-NGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACR 188 KE +D AV+ +++G + N FQ ++AL I + + + P Sbjct: 127 SKE--DSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 184 Query: 189 D---YWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWR 245 Y+ Y GS TTP C+E ++W + K+P+ + +Q + L E++ + + N R Sbjct: 185 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQ-KLNMKDNVR 243 Query: 246 PPQPINNRVVRAS 258 P QP+ R V S Sbjct: 244 PLQPLGKRQVFKS 256 >4G7A-A nrPDB Length = 248 Score = 117 bits (292), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 76/248 (30%), Positives = 121/248 (48%), Gaps = 30/248 (12%) Query: 1 MAKEWGYASHNGPDHWHELFPN---AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAK 57 + EW Y GP+HW +L P K +NQSP+ + K + +L ++ Y Sbjct: 22 LEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINI-DKKYKVKANLPKLNLYYKTAKES 80 Query: 58 TILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAE 117 ++NNG T ++ + D ++ L Y+L+QFH H SEHT++ Y E Sbjct: 81 EVVNNGHTIQINIKE--DNTL---NYLGEKYQLKQFHFH------TPSEHTIEKKSYPLE 129 Query: 118 LHLVHWNPKYNTFKEALKQRDG-IAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFT 176 +H VH K DG I V+G+ K+G N E L+ +G++ Sbjct: 130 IHFVH------------KTEDGKILVVGVMAKLGKTNKELDKILNVAPA--EEGEKILDK 175 Query: 177 KFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEP 236 + + L P + Y TY GS TTPPC E + W++LK+P+++S Q+ KL+S++ + N P Sbjct: 176 NLNLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVNPNNRP 235 Query: 237 PVPLVSNW 244 + S W Sbjct: 236 VQEINSRW 243 >4XZ5-A nrPDB Length = 233 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 84/260 (32%), Positives = 116/260 (44%), Gaps = 42/260 (16%) Query: 5 WGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 WGY GP +W EL P G+NQSP+ L + SL + V Y + K ++ Sbjct: 4 WGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGFDVYYRETALK-LI 62 Query: 61 NNGKTCRV-VFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELH 119 NNG T +V + +Y + + G Y L Q+H H S EH DG Y E+H Sbjct: 63 NNGHTLQVNIPLGSYIK--INGHR----YELLQYHFHTPS------EHQRDGFNYPMEMH 110 Query: 120 LVHWNPKYNTFKEALKQRDG-IAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKF 178 LVH K DG +AVI I + G EN + L + K + K Sbjct: 111 LVH------------KDGDGNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKI 158 Query: 179 DPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPV 238 P+ FPA + ++ Y GS TTPPC E + W++ K+P+ S Q+ K+ L Sbjct: 159 HPAKFFPADKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYLG-------- 210 Query: 239 PLVSNWRPPQPINNRVVRAS 258 SN RP Q N R + S Sbjct: 211 ---SNARPVQRQNARTLLKS 227 >6EKI-A nrPDB Length = 226 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 80/265 (30%), Positives = 120/265 (45%), Gaps = 62/265 (23%) Query: 5 WGYASHNGPDHW----HELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 W Y GP HW +E G+NQSPV++ ++ + + L+ ++Y G + +I Sbjct: 6 WSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDI-SRIV--EAELEKIKINYSSGGS-SIT 61 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPY--------RLRQFHLHWGSSDDHGSEHTVDGV 112 NNG T +V ++ PG Y L+QFH H SEHT+ G Sbjct: 62 NNGHTIKVSYE-------------PGSYIIVDGIRFELKQFHFH------APSEHTIKGK 102 Query: 113 KYAAELHLVHWNPKYNTFKEALKQRDG-IAVIGIFLKIGHENGEFQIFLDALDKIKTKGK 171 Y E H VH + +DG +AVIG+ K G +N I + + GK Sbjct: 103 SYPFEAHFVHAD------------KDGNLAVIGVIFKEGKKN---PIIEKIWENLPEAGK 147 Query: 172 EAPFT-KFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLS 230 K + L P + Y+ Y GS TTPPC E + W++++E M +S +Q+ K R L+ Sbjct: 148 TIKLAHKINAYDLLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMG 207 Query: 231 SAENEPPVPLVSNWRPPQPINNRVV 255 N RP QP+N R++ Sbjct: 208 GDTN----------RPVQPLNARMI 222 >5HPJ-A nrPDB Length = 217 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/255 (28%), Positives = 118/255 (46%), Gaps = 43/255 (16%) Query: 4 EWGYASHNGPDHWHELFPN-AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNN 62 EW Y +G +HW + F A+G NQ+P++++ L P + Y+G ++NN Sbjct: 1 EWSYTGEHGTEHWGDSFATCAEGVNQTPIDINQTT---QAELAPLHLDYEG-QVTELVNN 56 Query: 63 GKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVH 122 G T + T ++ G + L+QFH H S E+ + G +Y E H VH Sbjct: 57 GHTIQANL--TGKNTLTVDGKT---FELKQFHFHTPS------ENYLKGKQYPLEAHFVH 105 Query: 123 WNPKYNTFKEALKQRDGIAVIGIFLKIG-HENGEFQIFLDALDKIKTKGKEAPFTK-FDP 180 K +AV+ + G N E L + I +KG+ + +P Sbjct: 106 ATDK-----------GELAVVAVMFDFGPRSNNELTTLLAS---IPSKGQTVELKEALNP 151 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 + L P R+Y+ + GS TTPPC E + W +++EP T S Q KL++++ Sbjct: 152 ADLLPRDREYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQAVMG---------- 201 Query: 241 VSNWRPPQPINNRVV 255 +N RP QP+N R++ Sbjct: 202 -NNARPLQPLNARLI 215 >1KOQ-A nrPDB Length = 223 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 74/255 (29%), Positives = 106/255 (41%), Gaps = 41/255 (16%) Query: 5 WGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 WGY H+ P+ W L + G+NQSPV + P+++ V+Y S + Sbjct: 4 WGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITETVSGKLPAIK---VNYKP-SMVDVE 59 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 NNG T +V + + + + G Y L+QFH H S E+ + G + E H Sbjct: 60 NNGHTIQVNYPEGGNTLTVNGRT----YTLKQFHFHVPS------ENQIKGRTFPMEAHF 109 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 VH L + V+ + + G NG + + T GK FD Sbjct: 110 VH-----------LDENKQPLVLAVLYEAGKTNGRLSSIWNVMPM--TAGKVKLNQPFDA 156 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 S L P Y+ + GS TTPPC E + WL+LK + Q K + S N Sbjct: 157 STLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSENN------ 210 Query: 241 VSNWRPPQPINNRVV 255 RP QP+N RVV Sbjct: 211 ----RPVQPLNARVV 221 >4XIW-A nrPDB Length = 239 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 72/261 (27%), Positives = 107/261 (40%), Gaps = 37/261 (14%) Query: 5 WGYASHNGPDHWHELFPNAKGENQSPVE--LHTKDIRHDPSLQPWSVSYDGGSAKTILNN 62 W Y GP W + A G+ QSP+ L+T + D + + +Y +LN Sbjct: 4 WNYGEVAGPPTWKGVC--ATGKRQSPINIPLNTSAPKVDAEMGEFDFAYGSFEKCDVLNT 61 Query: 63 GKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVH 122 G V + + + L L QFH H SEH +DG +YA E HLVH Sbjct: 62 GHGTMQVNFPAGNLAFIGNMEL----ELLQFHFH------APSEHAMDGRRYAMEAHLVH 111 Query: 123 WNPKYNTFKEALKQRDGIAVIGIFLKIGH--ENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 N K +AV+GI L+ G +N L+ ++ K +P +P Sbjct: 112 KN----------KSTGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSP-KGINP 160 Query: 181 SCLFP-----ACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENE 235 L P R + Y GS TTPPC E + W + +P+ V Q+ + + Sbjct: 161 VMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFVGDNKT- 219 Query: 236 PPVPLVSNWRPPQPINNRVVR 256 +N RP Q +N+R+V Sbjct: 220 ----YATNTRPLQLLNSRLVE 236 >4TWL-A nrPDB Length = 246 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/253 (29%), Positives = 108/253 (42%), Gaps = 40/253 (15%) Query: 11 NGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTC 66 NGP++W L P KG QSP++L + D +L +Y A+ + N+G Sbjct: 13 NGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNYRAVDAR-LRNSGHDV 71 Query: 67 RVVFDDTYDRSMLRGGPLP---GPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHW 123 V F G L Y+L++ H H SEH ++G ++ E LVH Sbjct: 72 LVDFKGN-------AGSLSINRVEYQLKRIHFH------SPSEHEMNGERFDLEAQLVH- 117 Query: 124 NPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGK-EAPFTKFDPSC 182 E+ Q+ AV+ I + G + D + + K E DP+ Sbjct: 118 --------ESQDQKR--AVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEINAGVVDPNQ 167 Query: 183 LFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVS 242 L Y+ Y GSFT PPC E I W ++++ TVS Q+ LL A NE ++ Sbjct: 168 LQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVL----LLKQAVNENA---IN 220 Query: 243 NWRPPQPINNRVV 255 N RP QP N R V Sbjct: 221 NARPLQPTNFRSV 233 >1Y7W-A nrPDB Length = 291 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 71/261 (27%), Positives = 106/261 (40%), Gaps = 48/261 (18%) Query: 20 FPNAKGENQSPVELHTKDIRHDPSLQPWS------VSYDGGSAKTI-LNNGKT-----CR 67 +P G NQSP++++T + S S ++ DG A I L N K + Sbjct: 43 YPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGAQADGITLTNAKVDLEQGMK 102 Query: 68 VVFDD-TYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPK 126 V FD + + G + QFH H SEHT++G+ Y ELH+V Sbjct: 103 VTFDQPAANLPTIEIGGTTKSFVPIQFHFHH-----FLSEHTINGIHYPLELHIVMQEQD 157 Query: 127 YNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALD-KIKTKGKEAPFTKFDPSC--- 182 A +AVIGI K ENG+ FL++L +I+ K + + D Sbjct: 158 PADVATAQ-----LAVIGIMYKY-SENGD--AFLNSLQTQIEGKIGDGTASYGDTGVSID 209 Query: 183 -------LFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENE 235 L P+ Y Y GS TTP C+E + W + P V+ +QM + A Sbjct: 210 NINVKTQLLPSSLKYAGYDGSLTTPGCDERVKWHVFTTPREVTREQMKLFVDVTMGAHAG 269 Query: 236 PPVPLVSNWRPPQPINNRVVR 256 V +NNR+++ Sbjct: 270 ADV-----------VNNRMIQ 279 >5TT3-A nrPDB Length = 234 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 67/264 (25%), Positives = 107/264 (40%), Gaps = 52/264 (19%) Query: 4 EWGYAS-HNGPDHWHELFPN----AKGENQSPVEL----HTKDIRHDPSLQPWSVSYDGG 54 +W Y + NGP W +L + G++QSP+ + HT+D LQ Y Sbjct: 9 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQD---KADLQ---FKYAAS 62 Query: 55 SAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKY 114 K + T + F+ T + RG Y L H H E ++ Sbjct: 63 KPKAVFFTHHTLKASFEPT-NHINYRGHD----YVLDNVHFHAPM------EFLINNKTR 111 Query: 115 AAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAP 174 H VH + K + V+ I + G EN L+ + K K KE Sbjct: 112 PLSAHFVHKDAK-----------GRLLVLAIGFEEGKENPNLDPILEGIQK-KQNFKEVA 159 Query: 175 FTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAEN 234 F P + +Y+ + GS T PPC E + W +++EP+ VS+ Q+A+++ + ++ N Sbjct: 160 LDAFLPKSI-----NYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPN 214 Query: 235 EPPVPLVSNWRPPQPINNRVVRAS 258 + RP QP N V+ S Sbjct: 215 Q---------RPVQPDYNTVIIKS 229 >3B1B-A nrPDB Length = 377 Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 46/140 (32%), Positives = 65/140 (46%), Gaps = 17/140 (12%) Query: 92 QFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDG--IAVIGIFLKI 149 QFH H SEH + G Y ELH+VH E L+ G +V GI ++ Sbjct: 161 QFHFH------STSEHLLAGKIYPLELHIVH------QVTEKLEACKGGCFSVTGILFQL 208 Query: 150 --GHENGEFQ-IFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTPPCEECI 206 G +N + IF + + T T L P+ RDY TY+GS TTPPC E + Sbjct: 209 DNGPDNELLEPIFANMPSREGTFSNLPAGTTIKLGELLPSDRDYVTYEGSLTTPPCSEGL 268 Query: 207 VWLLLKEPMTVSSDQMAKLR 226 +W ++ +P +S Q + R Sbjct: 269 LWHVMTQPQRISFGQWNRYR 288 >3Q31-A nrPDB Length = 244 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 62/240 (25%), Positives = 96/240 (40%), Gaps = 39/240 (16%) Query: 2 AKEWGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAK 57 A ++ Y GP +W+ L AKG++QSP+ + + I + S GS K Sbjct: 8 ANKFNYTGLGGPLNWYGLDEANEACAKGKHQSPIVIDSAAIDYAAS----------GSLK 57 Query: 58 TILNNGKTCRVVFDDTYDRSMLRGGPLPG---PYRLRQFHLHWGSSDDHGSEHTVDGVKY 114 L ++ + L G L Y L QFH H S EH V+ + Sbjct: 58 LDLPLADGSKLENLGFGLQVTLTNGSLTANSKTYTLAQFHFHTPS------EHHVNEEHF 111 Query: 115 AAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIF---LDALDKIKTKGK 171 E+H V F+ A K+ AV+G F ++ +F +D I G Sbjct: 112 PMEVHFV--------FQTAAKET---AVVGFFFQLSEVGDSVPLFDSVFAPIDNIPDAGT 160 Query: 172 EAPFTKFDPSCLFPACRDYWTYQ--GSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLL 229 + D L + YQ GS TTPPC E ++W L EP+ ++ K++ ++ Sbjct: 161 STTTGQLDFGGLLDHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKII 220 >5HJK-A nrPDB Length = 352 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 76 RSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPK 126 + + R G G YR+R+ + WG + H + H +GV +L V +NP+ Sbjct: 139 KVIARRGFHSGLYRIRELEVIWGENRLH-TIHKENGVLIKVDLSKVFFNPR 188 >5KHR-J nrPDB Length = 620 Score = 30.0 bits (66), Expect = 0.99, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 4/36 (11%) Query: 149 IGHENGEFQI----FLDALDKIKTKGKEAPFTKFDP 180 + +NGE++ FLDAL+KIK G E K++P Sbjct: 411 VAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEP 446 >6G13-A nrPDB Length = 126 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Query: 90 LRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQ 136 + QF L ++DDHG+ V ++Y+ + L NP YN + E L+Q Sbjct: 73 MSQFKLTHQNNDDHGNP--VYFLRYSGAIKLDPKNPNYNKWLELLEQ 117 >6DQP-A nrPDB Length = 190 Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 124 NPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGK 171 +P TF E L+Q DG+ V K + +G + LD L + +GK Sbjct: 54 SPALKTFTEQLQQADGLIVATPVYKAAY-SGALKTLLDLLPERALQGK 100 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1Z93-A nrPDB 394 e-110 1FLJ-A nrPDB 393 e-110 4CNR-A nrPDB 371 e-103 4QK3-A nrPDB 368 e-102 6G4T-A nrPDB 367 e-102 3D0N-A nrPDB 356 5e-99 6FAF-A nrPDB 351 2e-97 1URT-A nrPDB 325 1e-89 1RJ5-A nrPDB 296 8e-81 2W2J-A nrPDB 295 1e-80 4LU3-A nrPDB 294 2e-80 5LL9-A nrPDB 280 5e-76 5DVX-A nrPDB 273 8e-74 4COQ-A nrPDB 269 9e-73 3FE4-A nrPDB 268 1e-72 5JN8-A nrPDB 268 2e-72 3ZNC-A nrPDB 260 5e-70 4X5S-A nrPDB 253 8e-68 6EKI-A nrPDB 243 5e-65 4G7A-A nrPDB 242 1e-64 4XZ5-A nrPDB 239 9e-64 4ETQ-X nrPDB 233 4e-62 5HPJ-A nrPDB 232 1e-61 6B9J-X nrPDB 231 3e-61 4XIW-A nrPDB 231 3e-61 1KOQ-A nrPDB 230 5e-61 4TWL-A nrPDB 215 1e-56 5TT3-A nrPDB 192 1e-49 1Y7W-A nrPDB 191 3e-49 3Q31-A nrPDB 187 5e-48 3B1B-A nrPDB 154 4e-38 Sequences not found previously or not previously below threshold: 5TTH-B nrPDB 31 0.42 3V65-B nrPDB 31 0.45 3V64-C nrPDB 31 0.65 1PQ3-A nrPDB 30 1.5 1BII-A nrPDB 29 2.9 1S7T-A nrPDB 29 3.2 CONVERGED! >1Z93-A nrPDB Length = 266 Score = 394 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 257/260 (98%), Positives = 258/260 (99%) Query: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 MAKEWGYASHNGPDHWHELFPNAKGENQSP+ELHTKDIRHDPSLQPWSVSYDGGSAKTIL Sbjct: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL Sbjct: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP Sbjct: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 S LFPA RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL Sbjct: 181 SSLFPASRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 Query: 241 VSNWRPPQPINNRVVRASFK 260 VSNWRPPQPINNRVVRASFK Sbjct: 241 VSNWRPPQPINNRVVRASFK 260 >1FLJ-A nrPDB Length = 260 Score = 393 bits (1009), Expect = e-110, Method: Composition-based stats. Identities = 237/259 (91%), Positives = 244/259 (94%) Query: 2 AKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILN 61 AKEWGYASHNGP+HWHEL+P AKG+NQSP+ELHTKDIRHDPSLQPWSVSYD GSAKTILN Sbjct: 2 AKEWGYASHNGPEHWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVSYDPGSAKTILN 61 Query: 62 NGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLV 121 NGKTCRVVFDDT+DRSMLRGGPL GPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLV Sbjct: 62 NGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLV 121 Query: 122 HWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPS 181 HWNPKYNTF EALKQ DGIAV+GIFLKIG E GEFQI LDALDKIKTKGKEAPF FDPS Sbjct: 122 HWNPKYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFNHFDPS 181 Query: 182 CLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLV 241 CLFPACRDYWTY GSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSL +SAENEPPVPLV Sbjct: 182 CLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLV 241 Query: 242 SNWRPPQPINNRVVRASFK 260 NWRPPQPI RVVRASFK Sbjct: 242 GNWRPPQPIKGRVVRASFK 260 >4CNR-A nrPDB Length = 262 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 140/256 (54%), Positives = 180/256 (70%) Query: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 M+ WGY HNGP+HWH+ FP A GE QSPV++ T + DP+L+P ++ Y +++ ++ Sbjct: 3 MSHHWGYDKHNGPEHWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGEATSRRMV 62 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 N+G + V +DD+ D+++L+ GPL G YRL QFH HWGSSDD GSEHTVD KYAAELHL Sbjct: 63 NDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL 122 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 VHWN KY F A ++ DG+AV+G+FLK+G N Q LDALD IKTKGK F FDP Sbjct: 123 VHWNTKYGDFGTAAQEPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP 182 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 L P DYWTY GS TTPP E + W++LKEP++VSS QM K R+L +AE EP + Sbjct: 183 GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPEELM 242 Query: 241 VSNWRPPQPINNRVVR 256 ++NWRP QP+ NR VR Sbjct: 243 LANWRPAQPLKNRQVR 258 >4QK3-A nrPDB Length = 249 Score = 368 bits (945), Expect = e-102, Method: Composition-based stats. Identities = 149/260 (57%), Positives = 182/260 (70%), Gaps = 11/260 (4%) Query: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 M+ WGY HNGP+HWH+ FP AKGE QSPV++ T ++DPSL+P SVSYD ++ IL Sbjct: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 NNG V FDD+ D+++L+GGPL G YRL QFH HWGS D GSEHTVD KYAAELHL Sbjct: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 VHWN KY F +A++Q DG+AV+GIFLK+G Q +D LD IKTKGK A FT FDP Sbjct: 121 VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP 180 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 L P DYWTY GS TTPP EC+ W++LKEP++VSS+Q+ K R L + Sbjct: 181 RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL-----------M 229 Query: 241 VSNWRPPQPINNRVVRASFK 260 V NWRP QP+ NR ++ASFK Sbjct: 230 VDNWRPAQPLKNRQIKASFK 249 >6G4T-A nrPDB Length = 274 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 128/259 (49%), Positives = 180/259 (69%), Gaps = 1/259 (0%) Query: 3 KEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNN 62 WGY +GP HWH+L+P A+G+ QSP+ + + + PSLQP +SY+ + +I NN Sbjct: 7 HGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNN 66 Query: 63 GKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVH 122 G + +V F+D+ DR+++ GGPL GPYRL+QFH HWG D GSEHTVDG + +ELHLVH Sbjct: 67 GHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVH 126 Query: 123 WN-PKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPS 181 WN KY+TF EA DG+AV+G+FL+ G E+ DAL ++ KG +A F+ F+P Sbjct: 127 WNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPK 186 Query: 182 CLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLV 241 L PA R YWTY GS TTPP E + W++L+EP+++S QM K RSLL ++E++ + +V Sbjct: 187 SLLPASRHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDDERIHMV 246 Query: 242 SNWRPPQPINNRVVRASFK 260 +N+RPPQP+ RVV+ASF+ Sbjct: 247 NNFRPPQPLKGRVVKASFR 265 >3D0N-A nrPDB Length = 264 Score = 356 bits (914), Expect = 5e-99, Method: Composition-based stats. Identities = 150/256 (58%), Positives = 183/256 (71%), Gaps = 1/256 (0%) Query: 5 WGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGK 64 WGY HNGP HW E FP A G+ QSP+E+ TK++++D SL+P S+ YD SAK I N+G Sbjct: 8 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGH 67 Query: 65 TCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN 124 + V FDDT ++S+LRGGPL G YRLRQ HLHWGS+DDHGSEH VDGV YAAELH+VHWN Sbjct: 68 SFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWN 127 Query: 125 P-KYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCL 183 KY +F EA + DG+AV+G+FL+IG N + Q D LD IK KGK+ FT FD L Sbjct: 128 SDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSL 187 Query: 184 FPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSN 243 P DYWTY GS T PP E + W++LK+P+ +SS Q+AK RSLL +AE E LVSN Sbjct: 188 LPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSN 247 Query: 244 WRPPQPINNRVVRASF 259 RPPQP+ R VRASF Sbjct: 248 HRPPQPLKGRKVRASF 263 >6FAF-A nrPDB Length = 261 Score = 351 bits (900), Expect = 2e-97, Method: Composition-based stats. Identities = 140/257 (54%), Positives = 184/257 (71%), Gaps = 1/257 (0%) Query: 4 EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNG 63 +WGY NGP+ W +L+P A G NQSPV++ T + +HD SL+P SVSY+ +AK I+N G Sbjct: 5 DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVG 64 Query: 64 KTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHW 123 + V F+D +RS+L+GGP YRL QFH HWGS+++HGSEHTVDGVKY+AELH+ HW Sbjct: 65 HSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHW 124 Query: 124 NP-KYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSC 182 N KY++ EA + DG+AVIG+ +K+G N + Q LDAL IKTKGK APFT FDPS Sbjct: 125 NSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPST 184 Query: 183 LFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVS 242 L P+ D+WTY GS T PP E + W++ KE ++VSS+Q+A+ RSLLS+ E + VP+ Sbjct: 185 LLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQH 244 Query: 243 NWRPPQPINNRVVRASF 259 N RP QP+ R VRASF Sbjct: 245 NNRPTQPLKGRTVRASF 261 >1URT-A nrPDB Length = 248 Score = 325 bits (833), Expect = 1e-89, Method: Composition-based stats. Identities = 114/240 (47%), Positives = 156/240 (65%), Gaps = 1/240 (0%) Query: 22 NAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRG 81 +A+G QSP+ + KD +DP L P VSYD S + + N G +V FDD+ + S + G Sbjct: 1 SAEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGISG 60 Query: 82 GPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNP-KYNTFKEALKQRDGI 140 GPL YRL+QFH HWG++D+ GSEH VDG Y AELHLVHWN KY +K+A +G+ Sbjct: 61 GPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGL 120 Query: 141 AVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTP 200 AVIG+FLK+G + Q +D L +++ K + FDPSCL PACRDYWTY GS TTP Sbjct: 121 AVIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRDYWTYPGSLTTP 180 Query: 201 PCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK 260 P E + W++ K P+ VS Q++ R+LL S E +V+N+RP QP+ +R +R+SF+ Sbjct: 181 PLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFR 240 >1RJ5-A nrPDB Length = 261 Score = 296 bits (757), Expect = 8e-81, Method: Composition-based stats. Identities = 95/265 (35%), Positives = 137/265 (51%), Gaps = 12/265 (4%) Query: 2 AKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSL---QPWSVSYDGGSAKT 58 W Y +G DHW +P G+ QSP+ + T + DP L QP G Sbjct: 2 GHHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPLD 61 Query: 59 ILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDD-HGSEHTVDGVKYAAE 117 + NNG T ++ T L G LP Y Q HLHWG GSEH ++ AAE Sbjct: 62 LHNNGHTVQLSLPPT-----LHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAAE 116 Query: 118 LHLVHWNPK-YNTFKEALKQRDGIAVIGIFLKIGH-ENGEFQIFLDALDKIKTKGKEAPF 175 LH+VH++ + Y++ EA ++ G+AV+GI +++G EN + L L +I+ K ++ Sbjct: 117 LHVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTSV 176 Query: 176 TKFDPSCLFPA-CRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAEN 234 F LFP ++ Y GS TTPPC + ++W + +S Q+ KL+ LSS E Sbjct: 177 PPFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEE 236 Query: 235 EPPVPLVSNWRPPQPINNRVVRASF 259 +P PLV N+R PQP+N R + ASF Sbjct: 237 DPSEPLVQNYRVPQPLNQRTIFASF 261 >2W2J-A nrPDB Length = 291 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 95/257 (36%), Positives = 148/257 (57%), Gaps = 15/257 (5%) Query: 16 WHELFPNAKGENQSPVELHTKDIRHDPSLQPWSV--SYDGGSAKTILNNGKTCRVVFDDT 73 W +FP+A GE QSP+ L++++ R+DPSL + +Y + N+G T +V+ Sbjct: 38 WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKS- 96 Query: 74 YDRSMLRGGPLPG--PYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPK-YNTF 130 +S+L GGPLP + L + HWG + GSEHTV+ + ELHL+HWN + + Sbjct: 97 --KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSI 154 Query: 131 KEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPA--CR 188 EA+ + GIA+I +F++IG E+ + + L I+ KGK F+P+ L P R Sbjct: 155 DEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLR 214 Query: 189 DYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVP-----LVSN 243 DYW Y+GS T PPC E + W+L + P+T+S Q+ + R L + + V L N Sbjct: 215 DYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDN 274 Query: 244 WRPPQPINNRVVRASFK 260 +RP QP+++RV+RA+F+ Sbjct: 275 FRPTQPLSDRVIRAAFQ 291 >4LU3-A nrPDB Length = 279 Score = 294 bits (753), Expect = 2e-80, Method: Composition-based stats. Identities = 90/265 (33%), Positives = 136/265 (51%), Gaps = 12/265 (4%) Query: 2 AKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDP---SLQPWSVSYDGGSAKT 58 + W Y +G DHW +P QSP+++ T + DP +LQP G Sbjct: 4 GQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLD 63 Query: 59 ILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHG-SEHTVDGVKYAAE 117 + NNG T ++ T L G LP Y Q HLHWG G SEH ++ AE Sbjct: 64 LHNNGHTVQLSLPST-----LYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAE 118 Query: 118 LHLVHWNPK-YNTFKEALKQRDGIAVIGIFLKIGH-ENGEFQIFLDALDKIKTKGKEAPF 175 LH+VH++ Y++ EA ++ G+AV+GI +++G +N ++ L L +++ K ++ Sbjct: 119 LHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSV 178 Query: 176 TKFDPSCLFPACR-DYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAEN 234 F+ L P Y+ Y GS TTPPC + ++W + +S +Q+ KL+ L S E Sbjct: 179 PPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEE 238 Query: 235 EPPVPLVSNWRPPQPINNRVVRASF 259 EP LV N+R QP+N R+V ASF Sbjct: 239 EPSKLLVQNYRALQPLNQRMVFASF 263 >5LL9-A nrPDB Length = 263 Score = 280 bits (715), Expect = 5e-76, Method: Composition-based stats. Identities = 86/264 (32%), Positives = 141/264 (53%), Gaps = 13/264 (4%) Query: 4 EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAKT--IL 60 +W Y +G + W + +P+ G QSP++LH+ +++D SL P Y+ + K + Sbjct: 3 KWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLT 62 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDD-HGSEHTVDGVKYAAELH 119 NNG + ++ S + L Y Q HLHWG+ +D HGSEHTV G +AAELH Sbjct: 63 NNGHSVKLNLP-----SDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELH 117 Query: 120 LVHWNPK-YNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKF 178 +VH+N Y A + +G+AV+ + +++G N + L +K KG+EA F Sbjct: 118 IVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGF 177 Query: 179 DPSCLFP-ACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPP 237 + L P +Y+ Y+GS TTPPC ++W + + P+ +S +Q+ L + L + P Sbjct: 178 NIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDP 237 Query: 238 VP--LVSNWRPPQPINNRVVRASF 259 P +++N+R Q + R+V SF Sbjct: 238 SPREMINNFRQVQKFDERLVYTSF 261 >5DVX-A nrPDB Length = 260 Score = 273 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 85/261 (32%), Positives = 132/261 (50%), Gaps = 15/261 (5%) Query: 4 EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS---YDGGSAKTIL 60 W Y G W + P G QSPV++ + P+L+P +S + Sbjct: 1 HWRY---GGDPPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLR 57 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 NNG + ++ + + G YR Q HLHWG++ GSEHTV+G ++ AE+H+ Sbjct: 58 NNGHSVQLTLPPGLEMKLGPG----REYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHV 113 Query: 121 VHWNPKYNTFKEALKQRDGIAVIGIFLKIG-HENGEFQIFLDALDKIKTKGKEAPFTKFD 179 VH + KY EAL + G+AV+ FL+ G EN ++ L L++I +G E D Sbjct: 114 VHLSTKYARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLD 173 Query: 180 PSCLFPAC-RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPV 238 S L P+ Y+ Y+GS TTPPC + ++W + + +++S+ Q+ L L + Sbjct: 174 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWGPGDS--- 230 Query: 239 PLVSNWRPPQPINNRVVRASF 259 L N+R QP+N RV+ ASF Sbjct: 231 RLQLNFRATQPLNGRVIEASF 251 >4COQ-A nrPDB Length = 247 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 87/258 (33%), Positives = 122/258 (47%), Gaps = 39/258 (15%) Query: 4 EWGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTI 59 WGY+ GP+HW +L P G+NQSP+++++ D L P SV Y AK + Sbjct: 25 HWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADA-VKACLAPVSVYYV-SDAKYV 82 Query: 60 LNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELH 119 +NNG T +VV + + L+QFH H SEHTV+G Y E H Sbjct: 83 VNNGHTIKVVMGGRGYVVV-----DGKRFYLKQFHFHAP------SEHTVNGKHYPFEAH 131 Query: 120 LVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFD 179 VH L + I V+G+F K+G EN E + + + K + D Sbjct: 132 FVH-----------LDKNGNITVLGVFFKVGKENPELEKVWRVMPEEPG-QKRHLTARID 179 Query: 180 PSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVP 239 P L P RDY+ Y GS TTPPC E + W++ KEP+ +S +Q+ K R ++ Sbjct: 180 PEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGF-------- 231 Query: 240 LVSNWRPPQPINNRVVRA 257 N RP QP+N R V Sbjct: 232 --DNNRPVQPLNARKVMK 247 >3FE4-A nrPDB Length = 278 Score = 268 bits (686), Expect = 1e-72, Method: Composition-based stats. Identities = 87/264 (32%), Positives = 146/264 (55%), Gaps = 15/264 (5%) Query: 4 EWGY-ASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGSAK-TIL 60 +W Y HW + +P G+ QSP+ L +R++PSL+ +++ Y+ + + ++ Sbjct: 3 DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 62 Query: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWG--SSDDHGSEHTVDGVKYAAEL 118 NNG T ++ T ++ G Y +Q H HWG SS+ GSEHTVDG+++ E+ Sbjct: 63 NNGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEI 118 Query: 119 HLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGH--ENGEFQIFLDALDKIKTKGKEAPFT 176 H+VH+N KY ++ A DG+AV+ F+++ + EN + F+ L IK G+ T Sbjct: 119 HIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 178 Query: 177 KFDPSCLFPA-CRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENE 235 D + P + Y+TY GS TTPPC E + W +L + + +S Q+ KL + L N+ Sbjct: 179 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNK 238 Query: 236 PPVPLVSNWRPPQPINNRVVRASF 259 + +++R QP+N+RVV ++F Sbjct: 239 ---TIHNDYRRTQPLNHRVVESNF 259 >5JN8-A nrPDB Length = 266 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 82/269 (30%), Positives = 126/269 (46%), Gaps = 16/269 (5%) Query: 2 AKEWGYASHNGPDHWHELFP-----NAKGENQSPVELHTKDIRHDPSLQPWSVS-YDGGS 55 W Y ++ L P N + + QSP+ + T + D L + S YD Sbjct: 2 ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 61 Query: 56 AKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYA 115 T+ NNG + ++ + +++ + GG LP PY+ +Q HLHW GSEH++DG +A Sbjct: 62 TWTVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFA 118 Query: 116 AELHLVHWNPKYNT--FKEALKQRDGIAVIGIFLKIGHE-NGEFQIFLDALDKIKTKGKE 172 E+H+VH K + KEA D IAV+ ++ G + N FQ ++AL I Sbjct: 119 MEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMS 178 Query: 173 APFTKFDPSCLFP---ACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLL 229 + L P R Y+ Y GS TTP C+E +VW + +EP+ + +Q+ L Sbjct: 179 TTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 238 Query: 230 SSAENEPPVPLVSNWRPPQPINNRVVRAS 258 + E V + N RP Q + R V S Sbjct: 239 YYDK-EQTVSMKDNVRPLQQLGQRTVIKS 266 >3ZNC-A nrPDB Length = 258 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 77/252 (30%), Positives = 121/252 (48%), Gaps = 16/252 (6%) Query: 12 GPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWS-VSYDGGSAKTILNNGKTCRVVF 70 GP+ W K QSP+ + T + +P L P+ V YD I NN T + Sbjct: 16 GPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTL 72 Query: 71 DDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTF 130 + + GG LP Y Q HLHW + +D+GSEH++DG +A E+H+VH K + Sbjct: 73 GGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH--KKLTSS 127 Query: 131 KEALKQRDGIAVIGIFLKIGHE-NGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRD 189 KE +D AV+ +++G + N FQ ++AL I + + + P Sbjct: 128 KE--DSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTK 185 Query: 190 ---YWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRP 246 Y+ Y GS TTP C+E ++W + K+P+ + +Q + L E++ + + N RP Sbjct: 186 MYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQK-LNMKDNVRP 244 Query: 247 PQPINNRVVRAS 258 QP+ R V S Sbjct: 245 LQPLGKRQVFKS 256 >4X5S-A nrPDB Length = 232 Score = 253 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 82/259 (31%), Positives = 129/259 (49%), Gaps = 38/259 (14%) Query: 3 KEWGYASHNGPDHWHELFPN---AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTI 59 W Y NGP++W +L P +NQSPV++ + + + L+ ++Y+ I Sbjct: 8 HHWSYEGENGPENWAKLNPEYFWCNLKNQSPVDI-SDNYKVHAKLEKLHINYNKAVNPEI 66 Query: 60 LNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELH 119 +NNG T +V + + + ++G Y L+QFH H SEHTV+G Y E+H Sbjct: 67 VNNGHTIQVNVLEDF-KLNIKG----KEYHLKQFHFHAP------SEHTVNGKYYPLEMH 115 Query: 120 LVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFD 179 LVH + IAVIG+F K G N E + +K +G + + Sbjct: 116 LVHK-----------DKDGNIAVIGVFFKEGKANPELDKVFK--NALKEEGSKVFDGSIN 162 Query: 180 PSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVP 239 + L P ++Y+TY GS TTPPC E ++W++LK+P+T S Q+ +S++ Sbjct: 163 INALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIMKH-------- 214 Query: 240 LVSNWRPPQPINNRVVRAS 258 +N RP QPIN+R + S Sbjct: 215 --NNNRPTQPINSRYILES 231 >6EKI-A nrPDB Length = 226 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 75/257 (29%), Positives = 114/257 (44%), Gaps = 44/257 (17%) Query: 4 EWGYASHNGPDHWHELF----PNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTI 59 W Y GP HW +L G+NQSPV++ + L+ ++Y G + +I Sbjct: 5 HWSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDISR---IVEAELEKIKINYSSGGS-SI 60 Query: 60 LNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELH 119 NNG T +V ++ + + L+QFH H SEHT+ G Y E H Sbjct: 61 TNNGHTIKVSYEPGSYIIVDGI-----RFELKQFHFHAP------SEHTIKGKSYPFEAH 109 Query: 120 LVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFT-KF 178 VH + +AVIG+ K G +N + + L + GK K Sbjct: 110 FVH-----------ADKDGNLAVIGVIFKEGKKNPIIEKIWENLPE---AGKTIKLAHKI 155 Query: 179 DPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPV 238 + L P + Y+ Y GS TTPPC E + W++++E M +S +Q+ K R L+ N Sbjct: 156 NAYDLLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMGGDTN---- 211 Query: 239 PLVSNWRPPQPINNRVV 255 RP QP+N R++ Sbjct: 212 ------RPVQPLNARMI 222 >4G7A-A nrPDB Length = 248 Score = 242 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 76/262 (29%), Positives = 121/262 (46%), Gaps = 38/262 (14%) Query: 1 MAKEWGYASHNGPDHWHELFPN---AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAK 57 + EW Y GP+HW +L P K +NQSP+ + K + +L ++ Y Sbjct: 22 LEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINID-KKYKVKANLPKLNLYYKTAKES 80 Query: 58 TILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAE 117 ++NNG T ++ + L Y+L+QFH H SEHT++ Y E Sbjct: 81 EVVNNGHTIQINIKEDN-----TLNYLGEKYQLKQFHFHTP------SEHTIEKKSYPLE 129 Query: 118 LHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTK 177 +H VH + I V+G+ K+G N E L+ +G++ Sbjct: 130 IHFVHKT-----------EDGKILVVGVMAKLGKTNKELDKILNVAPA--EEGEKILDKN 176 Query: 178 FDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPP 237 + + L P + Y TY GS TTPPC E + W++LK+P+++S Q+ KL+S++ + N Sbjct: 177 LNLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVNPNN--- 233 Query: 238 VPLVSNWRPPQPINNRVVRASF 259 RP Q IN+R + F Sbjct: 234 -------RPVQEINSRWIIEGF 248 >4XZ5-A nrPDB Length = 233 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 80/260 (30%), Positives = 110/260 (42%), Gaps = 38/260 (14%) Query: 4 EWGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTI 59 WGY GP +W EL P G+NQSP+ L + SL + V Y + K + Sbjct: 3 HWGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGFDVYYRETALK-L 61 Query: 60 LNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELH 119 +NNG T +V + G Y L Q+H H SEH DG Y E+H Sbjct: 62 INNGHTLQVNIP-LGSYIKINGH----RYELLQYHFHTP------SEHQRDGFNYPMEMH 110 Query: 120 LVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFD 179 LVH +AVI I + G EN + L + K + K Sbjct: 111 LVHK-----------DGDGNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKIH 159 Query: 180 PSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVP 239 P+ FPA + ++ Y GS TTPPC E + W++ K+P+ S Q+ K+ L S Sbjct: 160 PAKFFPADKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYLGS-------- 211 Query: 240 LVSNWRPPQPINNRVVRASF 259 N RP Q N R + S+ Sbjct: 212 ---NARPVQRQNARTLLKSW 228 >4ETQ-X nrPDB Length = 269 Score = 233 bits (595), Expect = 4e-62, Method: Composition-based stats. Identities = 86/228 (37%), Positives = 130/228 (57%), Gaps = 10/228 (4%) Query: 29 SPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPY 88 SP+ + TK + L+P + Y+ TI N GK R+ F Y + GG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGGY----ISGGFLPNEY 61 Query: 89 RLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN-PKYNTFKEALKQRDGIAVIGIFL 147 L H++WG DD+GS H +D KY+ E++LVHWN KY++++EA K DG+ +I IFL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 148 KI-GHENGEFQIFLDALDKIKTKGKEAPF-TKFDPSCLFPACRDYWTYQGSFTTPPCEEC 205 ++ H+N FQ ++ LD I++ APF + F L P+ DY+TY G TT Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 206 IVWLLLKEPMTVSSDQMAKLRSLLSSAENE-PPVPLVSNWRPPQPINN 252 VW++ P+ + SDQ++K R+LLS + +E P + N+R P +N+ Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >5HPJ-A nrPDB Length = 217 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 116/257 (45%), Gaps = 43/257 (16%) Query: 4 EWGYASHNGPDHWHELFPNA-KGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNN 62 EW Y +G +HW + F +G NQ+P++++ L P + Y+G ++NN Sbjct: 1 EWSYTGEHGTEHWGDSFATCAEGVNQTPIDINQTT---QAELAPLHLDYEG-QVTELVNN 56 Query: 63 GKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVH 122 G T + T ++ G + L+QFH H SE+ + G +Y E H VH Sbjct: 57 GHTIQANL--TGKNTLTVDG---KTFELKQFHFHTP------SENYLKGKQYPLEAHFVH 105 Query: 123 WNPKYNTFKEALKQRDGIAVIGIFLKIG-HENGEFQIFLDALDKIKTKGKEAPFTK-FDP 180 K +AV+ + G N E L I +KG+ + +P Sbjct: 106 ATDK-----------GELAVVAVMFDFGPRSNNELTTL---LASIPSKGQTVELKEALNP 151 Query: 181 SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL 240 + L P R+Y+ + GS TTPPC E + W +++EP T S Q KL++++ Sbjct: 152 ADLLPRDREYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQAVMG---------- 201 Query: 241 VSNWRPPQPINNRVVRA 257 +N RP QP+N R++ Sbjct: 202 -NNARPLQPLNARLILE 217 >6B9J-X nrPDB Length = 241 Score = 231 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 86/228 (37%), Positives = 130/228 (57%), Gaps = 10/228 (4%) Query: 29 SPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPY 88 SP+ + TK + L+P + Y+ TI N GK R+ F Y + GG LP Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGGY----ISGGFLPNEY 61 Query: 89 RLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN-PKYNTFKEALKQRDGIAVIGIFL 147 L H++WG DD+GS H +D KY+ E++LVHWN KY++++EA K DG+ +I IFL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 148 KI-GHENGEFQIFLDALDKIKTKGKEAPF-TKFDPSCLFPACRDYWTYQGSFTTPPCEEC 205 ++ H+N FQ ++ LD I++ APF + F L P+ DY+TY G TT Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 206 IVWLLLKEPMTVSSDQMAKLRSLLSSAENE-PPVPLVSNWRPPQPINN 252 VW++ P+ + SDQ++K R+LLS + +E P + N+R P +N+ Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >4XIW-A nrPDB Length = 239 Score = 231 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 71/261 (27%), Positives = 107/261 (40%), Gaps = 37/261 (14%) Query: 5 WGYASHNGPDHWHELFPNAKGENQSPVEL--HTKDIRHDPSLQPWSVSYDGGSAKTILNN 62 W Y GP W + A G+ QSP+ + +T + D + + +Y +LN Sbjct: 4 WNYGEVAGPPTWKGVC--ATGKRQSPINIPLNTSAPKVDAEMGEFDFAYGSFEKCDVLNT 61 Query: 63 GKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVH 122 G V + + + L L QFH H SEH +DG +YA E HLVH Sbjct: 62 GHGTMQVNFPAGNLAFIGNMEL----ELLQFHFHAP------SEHAMDGRRYAMEAHLVH 111 Query: 123 WNPKYNTFKEALKQRDGIAVIGIFLKIGH--ENGEFQIFLDALDKIKTKGKEAPFTKFDP 180 N K +AV+GI L+ G +N L+ ++ K +P +P Sbjct: 112 KN----------KSTGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSP-KGINP 160 Query: 181 SCLFPAC-----RDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENE 235 L P R + Y GS TTPPC E + W + +P+ V Q+ + + Sbjct: 161 VMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFVGDNK-- 218 Query: 236 PPVPLVSNWRPPQPINNRVVR 256 +N RP Q +N+R+V Sbjct: 219 ---TYATNTRPLQLLNSRLVE 236 >1KOQ-A nrPDB Length = 223 Score = 230 bits (586), Expect = 5e-61, Method: Composition-based stats. Identities = 74/258 (28%), Positives = 103/258 (39%), Gaps = 41/258 (15%) Query: 4 EWGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTI 59 WGY H+ P+ W L + G+NQSPV + L V+Y S + Sbjct: 3 HWGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITET---VSGKLPAIKVNYKP-SMVDV 58 Query: 60 LNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELH 119 NNG T +V + + + + G Y L+QFH H SE+ + G + E H Sbjct: 59 ENNGHTIQVNYPEGGNTLTVNG----RTYTLKQFHFHVP------SENQIKGRTFPMEAH 108 Query: 120 LVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFD 179 VH L + V+ + + G NG + + T GK FD Sbjct: 109 FVH-----------LDENKQPLVLAVLYEAGKTNGRLSSIWNVMPM--TAGKVKLNQPFD 155 Query: 180 PSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVP 239 S L P Y+ + GS TTPPC E + WL+LK + Q K + S N Sbjct: 156 ASTLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSENN----- 210 Query: 240 LVSNWRPPQPINNRVVRA 257 RP QP+N RVV Sbjct: 211 -----RPVQPLNARVVIE 223 >4TWL-A nrPDB Length = 246 Score = 215 bits (548), Expect = 1e-56, Method: Composition-based stats. Identities = 75/263 (28%), Positives = 112/263 (42%), Gaps = 36/263 (13%) Query: 1 MAKEWGY--ASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGG 54 + E+ Y + NGP++W L P KG QSP++L + D +L +Y Sbjct: 1 VEDEFSYIDGNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNYRAV 60 Query: 55 SAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKY 114 A+ + N+G V F + Y+L++ H H SEH ++G ++ Sbjct: 61 DAR-LRNSGHDVLVDFKGNAGSLSIN----RVEYQLKRIHFH------SPSEHEMNGERF 109 Query: 115 AAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGK-EA 173 E LVH E+ Q+ AV+ I + G + D + + K E Sbjct: 110 DLEAQLVH---------ESQDQKR--AVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEI 158 Query: 174 PFTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAE 233 DP+ L Y+ Y GSFT PPC E I W ++++ TVS Q+ LL A Sbjct: 159 NAGVVDPNQLQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVL----LLKQAV 214 Query: 234 NEPPVPLVSNWRPPQPINNRVVR 256 NE ++N RP QP N R V Sbjct: 215 NENA---INNARPLQPTNFRSVF 234 >5TT3-A nrPDB Length = 234 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 60/260 (23%), Positives = 100/260 (38%), Gaps = 44/260 (16%) Query: 4 EWGYAS-HNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKT 58 +W Y + NGP W +L + G++QSP+ + H Y K Sbjct: 9 KWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIE--HYYHTQDKADLQFKYAASKPKA 66 Query: 59 ILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAEL 118 + T + F+ T + RG Y L H H E ++ Sbjct: 67 VFFTHHTLKASFEPT-NHINYRGHD----YVLDNVHFHAPM------EFLINNKTRPLSA 115 Query: 119 HLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKF 178 H VH + K + V+ I + G EN L+ + K+ F + Sbjct: 116 HFVHKDAK-----------GRLLVLAIGFEEGKENPNLDPILEGIQ------KKQNFKEV 158 Query: 179 DPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPV 238 P +Y+ + GS T PPC E + W +++EP+ VS+ Q+A+++ + ++ N+ Sbjct: 159 ALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQ--- 215 Query: 239 PLVSNWRPPQPINNRVVRAS 258 RP QP N V+ S Sbjct: 216 ------RPVQPDYNTVIIKS 229 >1Y7W-A nrPDB Length = 291 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 75/273 (27%), Positives = 107/273 (39%), Gaps = 47/273 (17%) Query: 16 WHEL-------FPNAKGENQSPVELHTKDIRHDPSLQPWS------VSYDGGSAKTI-LN 61 W L +P G NQSP++++T + S S ++ DG A I L Sbjct: 32 WPGLQEGGTTKYPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGAQADGITLT 91 Query: 62 NGK-----TCRVVFD-DTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYA 115 N K +V FD + + G + QFH H SEHT++G+ Y Sbjct: 92 NAKVDLEQGMKVTFDQPAANLPTIEIGGTTKSFVPIQFHFHH-----FLSEHTINGIHYP 146 Query: 116 AELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALD-KIKTKGKEAP 174 ELH+V A +AVIGI K ENG FL++L +I+ K + Sbjct: 147 LELHIVMQEQDPADVATAQ-----LAVIGIMYKY-SENG--DAFLNSLQTQIEGKIGDGT 198 Query: 175 FTKFDPS----------CLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAK 224 + D L P+ Y Y GS TTP C+E + W + P V+ +QM Sbjct: 199 ASYGDTGVSIDNINVKTQLLPSSLKYAGYDGSLTTPGCDERVKWHVFTTPREVTREQMKL 258 Query: 225 LRSLLSSAENEPPVPLVSNWRPPQPINNRVVRA 257 + A V N R Q + +R V Sbjct: 259 FVDVTMGAHAGADVV---NNRMIQDLGDREVYK 288 >3Q31-A nrPDB Length = 244 Score = 187 bits (474), Expect = 5e-48, Method: Composition-based stats. Identities = 58/240 (24%), Positives = 94/240 (39%), Gaps = 33/240 (13%) Query: 2 AKEWGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAK 57 A ++ Y GP +W+ L AKG++QSP+ + + I + S + Sbjct: 8 ANKFNYTGLGGPLNWYGLDEANEACAKGKHQSPIVIDSAAIDYAAS-GSLKLDLPLADGS 66 Query: 58 TILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAE 117 + N G +V + + Y L QFH H SEH V+ + E Sbjct: 67 KLENLGFGLQVTLTNGSLTAN------SKTYTLAQFHFHTP------SEHHVNEEHFPME 114 Query: 118 LHLVHWNPKYNTFKEALKQRDGIAVIGIFLK---IGHENGEFQIFLDALDKIKTKGKEAP 174 +H V F+ A K+ AV+G F + +G F +D I G Sbjct: 115 VHFV--------FQTAAKET---AVVGFFFQLSEVGDSVPLFDSVFAPIDNIPDAGTSTT 163 Query: 175 FTKFDPSCLFPACRDY--WTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSA 232 + D L + + Y GS TTPPC E ++W L EP+ ++ K++ ++ Sbjct: 164 TGQLDFGGLLDHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKIIKYN 223 >3B1B-A nrPDB Length = 377 Score = 154 bits (389), Expect = 4e-38, Method: Composition-based stats. Identities = 65/274 (23%), Positives = 97/274 (35%), Gaps = 57/274 (20%) Query: 2 AKEWGYASHNGPDHW------HELFPNAKGENQSPVE------LHTKDIRHDPSLQPWSV 49 W NG ++W + G QSP+ L K + LQ Sbjct: 37 GDHWD-HGLNG-ENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQ-TQW 93 Query: 50 SYD----GGSAKTILNNGKTCRV----VFDDTYDRSMLRGGPLPGPY------------- 88 SY G++ ++NNG T +V + ++ Sbjct: 94 SYPDLMSNGTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAAD 153 Query: 89 ----RLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDG--IAV 142 QFH H SEH + G Y ELH+VH E L+ G +V Sbjct: 154 RVTAVPTQFHFH------STSEHLLAGKIYPLELHIVH------QVTEKLEACKGGCFSV 201 Query: 143 IGIFLKI--GHENGEFQIFLDALDK-IKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTT 199 GI ++ G +N + + T T L P+ RDY TY+GS TT Sbjct: 202 TGILFQLDNGPDNELLEPIFANMPSREGTFSNLPAGTTIKLGELLPSDRDYVTYEGSLTT 261 Query: 200 PPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAE 233 PPC E ++W ++ +P +S Q + R + E Sbjct: 262 PPCSEGLLWHVMTQPQRISFGQWNRYRLAVGLKE 295 >5TTH-B nrPDB Length = 672 Score = 31.2 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 23/50 (46%), Gaps = 4/50 (8%) Query: 207 VWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVR 256 +W + EP +S Q + ++ A ++P L +R P+N R + Sbjct: 247 LW--MMEPKDISEWQHEEFYRYVAQAYDKPRYTLH--YRADAPLNIRSIF 292 >3V65-B nrPDB Length = 386 Score = 31.2 bits (69), Expect = 0.45, Method: Composition-based stats. Identities = 15/108 (13%), Positives = 34/108 (31%), Gaps = 15/108 (13%) Query: 46 PWSVSYDGGSAKTILNNGKTC-RVVFDDTYDRSMLRGGPLPGPYRLRQFH-------LHW 97 ++ Y G + R D ++ ++++ G LP P+ + F H Sbjct: 250 GLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQG-LPHPFAITVFEDSLYWTDWHT 308 Query: 98 GSSDDHG------SEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDG 139 S + E + + + ++H +H + G Sbjct: 309 KSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGG 356 >3V64-C nrPDB Length = 349 Score = 30.8 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 15/108 (13%), Positives = 34/108 (31%), Gaps = 15/108 (13%) Query: 46 PWSVSYDGGSAKTILNNGKTC-RVVFDDTYDRSMLRGGPLPGPYRLRQFH-------LHW 97 ++ Y G + R D ++ ++++ G LP P+ + F H Sbjct: 207 GLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQG-LPHPFAITVFEDSLYWTDWHT 265 Query: 98 GSSDDHG------SEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDG 139 S + E + + + ++H +H + G Sbjct: 266 KSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGG 313 >1PQ3-A nrPDB Length = 306 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 20/48 (41%), Gaps = 9/48 (18%) Query: 25 GENQSPVELHTKDIRHDPSLQPW-------SVSYDGGS--AKTILNNG 63 G+ Q P+ L DP+L P ++Y G A+ I N G Sbjct: 217 GKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTG 264 >1BII-A nrPDB Length = 365 Score = 28.5 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 17/39 (43%), Gaps = 1/39 (2%) Query: 9 SHNGPDHWHELFPNAKGENQS-PVELHTKDIRHDPSLQP 46 GP++W AKG QS V+L T ++ S Sbjct: 77 EQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGG 115 >1S7T-A nrPDB Length = 348 Score = 28.5 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 19/61 (31%), Gaps = 15/61 (24%) Query: 9 SHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRV 68 GP++W AKG QS L+ Y+ + T +V Sbjct: 53 EQEGPEYWERETQKAKGNEQS----------FRVDLRTLLGYYNQSKGGS-----HTIQV 97 Query: 69 V 69 + Sbjct: 98 I 98 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.133 0.423 Lambda K H 0.267 0.0412 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,400,994 Number of Sequences: 36641 Number of extensions: 459064 Number of successful extensions: 1289 Number of sequences better than 10.0: 37 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 1009 Number of HSP's gapped (non-prelim): 77 length of query: 260 length of database: 10,336,785 effective HSP length: 95 effective length of query: 165 effective length of database: 6,855,890 effective search space: 1131221850 effective search space used: 1131221850 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.9 bits)