BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07356 (339 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4X9P-A nrPDB 683 0.0 5N7D-A nrPDB 629 0.0 1HM6-A nrPDB 348 1e-96 1AIN-A nrPDB 343 8e-95 2ZHI-A nrPDB 306 6e-84 1I4A-A nrPDB 301 3e-82 2ZOC-A nrPDB 300 6e-82 1YII-A nrPDB 295 1e-80 1M9I-A nrPDB 293 5e-80 1AVC-A nrPDB 287 4e-78 1AII-A nrPDB 286 9e-78 1SAV-A nrPDB 280 6e-76 2IE7-A nrPDB 280 9e-76 1W3W-A nrPDB 275 2e-74 1DM5-A nrPDB 264 3e-71 6B3I-A nrPDB 254 4e-68 4MDV-A nrPDB 172 2e-43 1YCN-A nrPDB 153 1e-37 3BRX-A nrPDB 125 2e-29 1DK5-A nrPDB 116 1e-26 1BO9-A nrPDB 74 1e-13 3CHK-A nrPDB 62 5e-10 4EVF-A nrPDB 44 7e-05 5TCU-S1 nrPDB 32 0.38 1Y8N-A nrPDB 32 0.48 5ND9-j nrPDB 31 0.62 5T7V-S1 nrPDB 31 0.70 2JLW-A nrPDB 31 0.81 5HH5-A nrPDB 31 0.95 2WZQ-A nrPDB 30 1.1 3ES8-A nrPDB 30 1.2 2Z83-A nrPDB 30 2.2 5NJT-J nrPDB 29 2.2 5K8T-A nrPDB 29 2.7 4KKJ-A nrPDB 29 2.7 2BMF-A nrPDB 29 3.4 5UM7-A nrPDB 28 5.8 4N5C-A nrPDB 27 8.9 6AHD-N nrPDB 27 9.8 2C5U-A nrPDB 27 9.8 >4X9P-A nrPDB Length = 343 Score = 683 bits (1762), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/339 (97%), Positives = 336/339 (99%) Query: 1 MSTVHEILCKLSLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNIL 60 MSTVHEILCKLSLEGDHSTPPSAYGSVK YTNFDAERDALNIETA+KTKGVDEVTIVNIL Sbjct: 5 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNIL 64 Query: 61 TNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKG 120 TNRSN QRQDIAFAYQRRTKKEL SALKSALSGHLETVILGLLKTPAQYDASELKASMKG Sbjct: 65 TNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKG 124 Query: 121 LGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRA 180 LGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDI+SDTSGDFRKLMVALAKGRRA Sbjct: 125 LGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIVSDTSGDFRKLMVALAKGRRA 184 Query: 181 EDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDM 240 EDGSVIDYELIDQDAR+LYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDM Sbjct: 185 EDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDM 244 Query: 241 LESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDM 300 LESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDM Sbjct: 245 LESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDM 304 Query: 301 LKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 339 LKIRSEFK+KYGKSLYYYIQQDTKGDYQKALLYLCGGDD Sbjct: 305 LKIRSEFKKKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 343 >5N7D-A nrPDB Length = 427 Score = 629 bits (1622), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/318 (97%), Positives = 314/318 (98%) Query: 22 SAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKK 81 SAYGSVK YTNFDAERDALNIETA+KTKGVDEVTIVNILTNRSN QRQDIAFAYQRRTKK Sbjct: 110 SAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTKK 169 Query: 82 ELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQ 141 EL SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQ Sbjct: 170 ELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQ 229 Query: 142 EINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDA 201 EINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAR+LYDA Sbjct: 230 EINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDA 289 Query: 202 GVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQ 261 GVKRKGTDVPKWISIMTERSV HLQKVF+RYKSYSPYDMLESI+KEVKGDLENAFLNLVQ Sbjct: 290 GVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQ 349 Query: 262 CIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQ 321 CIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQ Sbjct: 350 CIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQ 409 Query: 322 DTKGDYQKALLYLCGGDD 339 DTKGDYQKALLYLCGGDD Sbjct: 410 DTKGDYQKALLYLCGGDD 427 >1HM6-A nrPDB Length = 346 Score = 348 bits (894), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 177/327 (54%), Positives = 237/327 (72%), Gaps = 4/327 (1%) Query: 12 SLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDI 71 +++G P SA V PY F+ D + A+ KGVDE TI+ ILT R+N QRQ I Sbjct: 24 TVKGSKGGPGSA---VSPYPTFNPSSDVEALHKAITVKGVDEATIIEILTKRTNAQRQQI 80 Query: 72 AFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEI 131 AY + K L ALK AL+GHLE V L LLKTPAQ+DA EL+A+MKGLGTDED+L EI Sbjct: 81 KAAYLQEKGKPLDEALKKALTGHLEEVALALLKTPAQFDADELRAAMKGLGTDEDTLNEI 140 Query: 132 ICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELI 191 + SRTN+E++EINRVYKE K DL KDI SDTSGD++K +++LAKG R+ED ++ D +L Sbjct: 141 LASRTNREIREINRVYKEELKRDLAKDITSDTSGDYQKALLSLAKGDRSEDLAIND-DLA 199 Query: 192 DQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGD 251 D DAR LY+AG +RKGTD+ +I+I+T RS HL++VF++Y YS +DM + + E+KGD Sbjct: 200 DTDARALYEAGERRKGTDLNVFITILTTRSYPHLRRVFQKYSKYSKHDMNKVLDLELKGD 259 Query: 252 LENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKY 311 +EN +V+C +KP++FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ Y Sbjct: 260 IENCLTVVVKCATSKPMFFAEKLHQAMKGIGTRHKTLIRIMVSRSEIDMNDIKACYQKLY 319 Query: 312 GKSLYYYIQQDTKGDYQKALLYLCGGD 338 G SL I +TKGDY+K L+ LCGGD Sbjct: 320 GISLCQAILDETKGDYEKILVALCGGD 346 >1AIN-A nrPDB Length = 314 Score = 343 bits (879), Expect = 8e-95, Method: Compositional matrix adjust. Identities = 170/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%) Query: 26 SVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPS 85 +V PY F+ D + A+ KGVDE TI++ILT R+N QRQ I AY + T K L Sbjct: 3 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 62 Query: 86 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145 LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR Sbjct: 63 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 122 Query: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKR 205 VY+E K DL KDI SDTSGDFR +++LAKG R+ED V + +L D DAR LY+AG +R Sbjct: 123 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 181 Query: 206 KGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQN 265 KGTDV + +I+T RS L++VF++Y YS +DM + + E+KGD+E +V+C + Sbjct: 182 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 241 Query: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ YG SL I +TKG Sbjct: 242 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 301 Query: 326 DYQKALLYLCGGD 338 DY+K L+ LCGG+ Sbjct: 302 DYEKILVALCGGN 314 >2ZHI-A nrPDB Length = 322 Score = 306 bits (785), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 158/315 (50%), Positives = 214/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+VK + F+A DA + A+K G DE I+ +L R+ QRQ+I AY+ ++L Sbjct: 9 GTVKAASGFNATEDAQVLRKAMKGLGTDEDAIIGVLACRNTAQRQEIRTAYKSTIGRDLL 68 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS LS + E VILG++ YD EL+ +MKG GTDE LIEI+ SR +E++ IN Sbjct: 69 EDLKSELSSNFEQVILGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRNPEEIRRIN 128 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y++ Y LE+DI SDTS F++++V+L G R E G+ +D L+ QDA++LY+AG K Sbjct: 129 QTYQQQYGRSLEEDICSDTSFMFQRVLVSLTAGGRDE-GNYLDDALVKQDAQDLYEAGEK 187 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 R GTD K++SI+ R+ HL VF+ YK S D+ +SIK E G E+A L +V+C++ Sbjct: 188 RWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMR 247 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 NKP YFA+RLY SMKG GT D LIR+MVSR+E+DML IR+ FKR YGKSLY +I+ DT Sbjct: 248 NKPAYFAERLYKSMKGLGTDDSTLIRVMVSRAEIDMLDIRANFKRLYGKSLYSFIKGDTS 307 Query: 325 GDYQKALLYLCGGDD 339 GDY+K LL LCGGDD Sbjct: 308 GDYRKVLLILCGGDD 322 >1I4A-A nrPDB Length = 318 Score = 301 bits (771), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 156/315 (49%), Positives = 213/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G VK + F+A DA + A+K G DE I+N+L RS QRQ+I AY+ ++L Sbjct: 5 GDVKAASGFNAAEDAQTLRKAMKGLGTDEDAIINVLAYRSTAQRQEIRTAYKTTIGRDLM 64 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS LSG+ E VILG++ YD EL+ +MKG GTDE LIEI+ SRT +E++ IN Sbjct: 65 DDLKSELSGNFEQVILGMMTPTVLYDVQELRKAMKGAGTDEGCLIEILASRTPEEIRRIN 124 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y+ Y LE DI SDTS F++++V+L+ G R E + +D L+ QDA++LY+AG K Sbjct: 125 QTYQLQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDE-SNYLDDALMRQDAQDLYEAGEK 183 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+++++ R+ HL VF+ YK + D+ +SIK E G E+A L +V+C++ Sbjct: 184 KWGTDEVKFLTVLCSRNRNHLLHVFDEYKRIAQKDIEQSIKSETSGSFEDALLAIVKCMR 243 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 NK YFA+RLY SMKG GT D LIR+MVSR+E+DML IR+ FKR YGKSLY +I+ DT Sbjct: 244 NKSAYFAERLYKSMKGLGTDDDTLIRVMVSRAEIDMLDIRANFKRLYGKSLYSFIKGDTS 303 Query: 325 GDYQKALLYLCGGDD 339 GDY+K LL LCGGDD Sbjct: 304 GDYRKVLLILCGGDD 318 >2ZOC-A nrPDB Length = 319 Score = 300 bits (768), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 153/315 (48%), Positives = 216/315 (68%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+VK + F+A DA + A+K G DE I+++L R+ QRQ+I AY+ ++L Sbjct: 6 GTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLI 65 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS LSG+ E VI+G++ YD EL+ +MKG GTDE LIEI+ SRT +E++ I+ Sbjct: 66 DDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRIS 125 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y++ Y LE DI SDTS F++++V+L+ G R E G+ +D L+ QDA++LY+AG K Sbjct: 126 QTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDE-GNYLDDALVRQDAQDLYEAGEK 184 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+++++ R+ HL VF+ YK S D+ +SIK E G E+A L +V+C++ Sbjct: 185 KWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMR 244 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 NK YFA++LY SMKG GT D LIR+MVSR+E+DML IR+ FKR YGKSLY +I+ DT Sbjct: 245 NKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTS 304 Query: 325 GDYQKALLYLCGGDD 339 GDY+K LL LCGGDD Sbjct: 305 GDYRKVLLVLCGGDD 319 >1YII-A nrPDB Length = 320 Score = 295 bits (756), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 150/315 (47%), Positives = 215/315 (68%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V ++ FDA DA + A+K G DE TI+ ILT+R+N QRQ+IA A++ ++L Sbjct: 6 GTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLV 65 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS L+G ET+++ L++ +DA LK ++KG GT+E L EI+ SRT E+Q I Sbjct: 66 DDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIK 125 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 +VY + Y+ +LE I +TSG F++L+V L + R DG V D L+++DA+ L+ AG Sbjct: 126 QVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRV-DEALVEKDAQVLFRAGEL 184 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD +I+I+ RSV HL++VF++Y + S + + E+I +E GDLE L +V+CI+ Sbjct: 185 KWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIR 244 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P YFA+ LY SMKG GT D LIR+MVSRSE+D+L IR EF++ + KSLY IQ+DT Sbjct: 245 SVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTS 304 Query: 325 GDYQKALLYLCGGDD 339 GDY+KALL LCGGDD Sbjct: 305 GDYRKALLLLCGGDD 319 >1M9I-A nrPDB Length = 672 Score = 293 bits (751), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 151/319 (47%), Positives = 213/319 (66%), Gaps = 4/319 (1%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G V+P +F+ + DA + A+K G DE TI++I+T+RSNVQRQ I ++ ++L Sbjct: 354 GDVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 413 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LKS +SG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E++ IN Sbjct: 414 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 473 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAR----ELYD 200 YKE Y LE + SDTSG FR+++++LA G R E G +D D E+ D Sbjct: 474 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIAD 533 Query: 201 AGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLV 260 K + ++++I+ RS HL++VF+ + + YD+ +IKKE+ GD+ +AF+ +V Sbjct: 534 TPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 593 Query: 261 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 320 Q ++NKPL+FAD+LY SMKG GT DK L RIMVSRSE+D+L IR EF KY KSL+ I+ Sbjct: 594 QSVKNKPLFFADKLYKSMKGAGTDDKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIE 653 Query: 321 QDTKGDYQKALLYLCGGDD 339 DT GD+ KALL LCGG+D Sbjct: 654 GDTSGDFLKALLALCGGED 672 Score = 287 bits (734), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 149/315 (47%), Positives = 214/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 GS+ + FD +DA + TA+K G D+ I++I+T+RSN QRQ++ +Y+ K+L Sbjct: 11 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 70 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++ Sbjct: 71 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 130 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 YK+ Y+ DLE DII DTSG F+K++V L +G R ED V+ +L+ QD ++LY+AG Sbjct: 131 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 189 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD ++I I+ RS HL+ VF+ Y + + SI+ E+ GD E L +V+CI+ Sbjct: 190 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 249 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT Sbjct: 250 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 309 Query: 325 GDYQKALLYLCGGDD 339 G+Y+K LL L GGDD Sbjct: 310 GEYKKTLLKLSGGDD 324 >1AVC-A nrPDB Length = 673 Score = 287 bits (735), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 148/315 (46%), Positives = 213/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 GS++ + +F+ +DA + A+K G D+ I+N++T+RSN QRQ+I Y+ K+L Sbjct: 12 GSIRDFPDFNPSQDAETLYNAMKGFGSDKEAIINLITSRSNKQRQEICQNYKSLYGKDLI 71 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++ Sbjct: 72 ADLKYELTGKFERLIVGLMRPPAYADAKEIKDAISGIGTDEKCLIEILASRTNEQIHQLV 131 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 YK+ Y+ DLE DI DTSG FRK++V L +G R ED V+ +L+ QD ++LY+AG Sbjct: 132 AAYKDAYERDLEADITGDTSGHFRKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 190 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD ++I I+ RS HL+ VF+ Y + + SI+ E+ GD E L +V+CI+ Sbjct: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT Sbjct: 251 STAEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310 Query: 325 GDYQKALLYLCGGDD 339 G+Y+K LL LCGGDD Sbjct: 311 GEYKKTLLKLCGGDD 325 Score = 284 bits (726), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 148/321 (46%), Positives = 213/321 (66%), Gaps = 8/321 (2%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V+P +F+ + DA + A+K G DE TI++I+T+RSN QRQ I ++ ++L Sbjct: 355 GTVRPAGDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNAQRQQIRQTFKSHFGRDLM 414 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LKS LSG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E+Q IN Sbjct: 415 ADLKSELSGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIQAIN 474 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAR------EL 198 + YKE Y LE + SDTSG F++++++LA G R E G D E +DA+ E+ Sbjct: 475 KAYKEDYHKTLEDALSSDTSGHFKRILISLATGNREEGGE--DRERAREDAQVAAEILEI 532 Query: 199 YDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLN 258 D K + +++ I+ RS L++VF+ + + YD+ +IKKE+ GD+ + F+ Sbjct: 533 ADTTSGDKSSLETRFMMILCTRSYPDLRRVFQEFVKMTNYDVEHTIKKEMSGDVRDVFVA 592 Query: 259 LVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYY 318 +VQ ++NKPL+FAD+LY SMKG GT +K L RIMVSRSE+D+L IR EF KY KSL+ Sbjct: 593 IVQSVKNKPLFFADKLYKSMKGAGTEEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652 Query: 319 IQQDTKGDYQKALLYLCGGDD 339 I+ DT G + KALL +CGG+D Sbjct: 653 IEGDTSGHFLKALLAICGGED 673 >1AII-A nrPDB Length = 323 Score = 286 bits (732), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 150/315 (47%), Positives = 209/315 (66%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V+ Y +F DA I+ A++ G DE +++ILT RSN QRQ I YQ KEL Sbjct: 10 GTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELK 69 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LK LSGH E +++ L+ PA +DA +LK SMKG GT+ED+LIEI+ +RT++++++I+ Sbjct: 70 DDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDIS 129 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y +YK L DI S+TSGDFRK ++ LA GRR E V D L QDA+ LY AG Sbjct: 130 QAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKV-DEHLAKQDAQILYKAGEN 188 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 R GTD K+ I+ RS L+ F+ Y++ S D+++SIK E+ G E+ L +V C++ Sbjct: 189 RWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVR 248 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 N P + A+RL+ ++KG GT + L RIMVSRSE+D+L IR+EFK+ YG SLY I+ DT Sbjct: 249 NTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTS 308 Query: 325 GDYQKALLYLCGGDD 339 GDY+ LL +CGGDD Sbjct: 309 GDYEITLLKICGGDD 323 >1SAV-A nrPDB Length = 320 Score = 280 bits (716), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 144/315 (45%), Positives = 208/315 (66%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V + FD DA + A+K G DE +I+ +LT+RSN QRQ+I+ A++ ++L Sbjct: 7 GTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLL 66 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS L+G E +I+ L+K YDA ELK ++KG GT+E L EII SRT +EL+ I Sbjct: 67 DDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIK 126 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 +VY+E Y + LE D++ DTSG +++++V L + R D ID ++QDA+ L+ AG Sbjct: 127 QVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAG-IDEAQVEQDAQALFQAGEL 185 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+I+I RSV HL+KVF++Y + S + + E+I +E G+LE L +V+ I+ Sbjct: 186 KWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIR 245 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P Y A+ LY +MKG GT D LIR+MVSRSE+D+ IR EF++ + SLY I+ DT Sbjct: 246 SIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTS 305 Query: 325 GDYQKALLYLCGGDD 339 GDY+KALL LCG DD Sbjct: 306 GDYKKALLLLCGEDD 320 >2IE7-A nrPDB Length = 318 Score = 280 bits (715), Expect = 9e-76, Method: Compositional matrix adjust. Identities = 142/315 (45%), Positives = 211/315 (66%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V ++ FD DA + A+K G DE +I+N+LT RSN QRQ IA ++ ++L Sbjct: 4 GTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLV 63 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + +KS L+G E +I+ L+K YDA ELK ++KG GTDE L EII SRT +EL+ I Sbjct: 64 NDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIK 123 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y+E Y ++LE D++ DTSG +++++V L + R D + ID ++ DA+ L+ AG Sbjct: 124 QAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPD-TAIDDAQVELDAQALFQAGEL 182 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+I+I+ RSV HL++VF++Y + S + + E+I +E G+LEN L +V+ I+ Sbjct: 183 KWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIR 242 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P Y A+ LY +MKG GT D LIR++VSRSE+D+ IR EF++ + SLY I+ DT Sbjct: 243 SIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTS 302 Query: 325 GDYQKALLYLCGGDD 339 GDY+KALL LCGG+D Sbjct: 303 GDYKKALLLLCGGED 317 >1W3W-A nrPDB Length = 327 Score = 275 bits (703), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 146/313 (46%), Positives = 206/313 (65%) Query: 26 SVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPS 85 +VK ++F+ + DA + A+K G +E I+++LT RSN QRQ IA +++ + K+L Sbjct: 14 TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73 Query: 86 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145 LKS LSG E +I+ L+ P +Y+A EL +MKGLGT E +IEI+ SRT +L+EI + Sbjct: 74 TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133 Query: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKR 205 Y+E Y + LE+DI +DTSG +++V L +G R + S +D L QDA++LY AG K Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGEKI 193 Query: 206 KGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQN 265 +GTD K+I+I+ RS HL +VFE Y+ + + +SIK E G LE A L +V+C QN Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253 Query: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 YFA+RLY +MKG GTRD LIR +VSRSE+D+ I+ FK+ YGK+L I +DT G Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313 Query: 326 DYQKALLYLCGGD 338 DY+ ALL L G D Sbjct: 314 DYKNALLSLVGSD 326 >1DM5-A nrPDB Length = 315 Score = 264 bits (675), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 134/312 (42%), Positives = 203/312 (65%), Gaps = 1/312 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+VKP+ +F++ DA + A+K G DE +I +IL RSN QRQ I Y K L Sbjct: 4 GTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQIKTDYTTLFGKHLE 63 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS LSG+ E L LL+ P ++ A +L A+MKGLGTD+++LI+I+C+++N ++ I Sbjct: 64 DELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGLGTDKNALIDILCTQSNAQIHAIK 123 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 +K +YK DLEK+IIS+TSG+F++L+V++ +G R ED V + +DA +Y AG Sbjct: 124 AAFKLLYKEDLEKEIISETSGNFQRLLVSMLQGGRKEDEPV-NAAHAAEDAAAIYQAGEG 182 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD ++ +++ RS L ++F Y S +L++I+ E GD++N L +V+ ++ Sbjct: 183 QIGTDESRFNAVLATRSYPQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVE 242 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 N+ YFA+RL+ +MKG GT DK LIRI+VSRSE+D+ I+ F+ YGKSLY +I D Sbjct: 243 NRFAYFAERLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADDCS 302 Query: 325 GDYQKALLYLCG 336 GDY+ LL + G Sbjct: 303 GDYKDLLLQITG 314 >6B3I-A nrPDB Length = 343 Score = 254 bits (649), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 135/318 (42%), Positives = 201/318 (63%), Gaps = 8/318 (2%) Query: 17 HSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQ 76 H+ S G FD +RDA + A K G +E I+ IL+ R++ +RQ I Y+ Sbjct: 32 HAKASSPQG-------FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYK 84 Query: 77 RRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRT 136 KEL LKS LSG+ E L LL P++Y A +L+ +MKGLGTDE LIE++C+RT Sbjct: 85 ATYGKELEEVLKSELSGNFEKTALALLDHPSEYAARQLQKAMKGLGTDESVLIEVLCTRT 144 Query: 137 NQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAR 196 N+E+ I Y+ ++ LE D+ DTSG+ +K++V+L + R E G +D +L QDA+ Sbjct: 145 NKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAK 203 Query: 197 ELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAF 256 +LYDAG R GTD + ++ +RS L+ F+ Y+ D+ E+I++E GDL+ A+ Sbjct: 204 DLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAY 263 Query: 257 LNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLY 316 L LV+C Q+ YFA+RLY SMKG GT ++ LIRI+V+R+EVD+ I+++F+ KY KSL Sbjct: 264 LTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIIVTRAEVDLQGIKAKFQEKYQKSLS 323 Query: 317 YYIQQDTKGDYQKALLYL 334 ++ DT GD++K L+ L Sbjct: 324 DMVRSDTSGDFRKLLVAL 341 >4MDV-A nrPDB Length = 375 Score = 172 bits (436), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 108/344 (31%), Positives = 180/344 (52%), Gaps = 26/344 (7%) Query: 14 EGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAF 73 G H P ++KP T F A DA + ++K G +E+ I+NIL R+N +RQ+I Sbjct: 22 HGKHYRP-----TIKPTTGFSASADAERLHRSMKGPGTNELAIINILARRTNYERQEICQ 76 Query: 74 AYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIIC 133 +Y+ K++L LKS SG V+ L+ A L +MKGLGT++ LIEI Sbjct: 77 SYKSLYKQDLKDDLKSDTSGDFRKVLCQLIVDTPYMLAKSLYYAMKGLGTNDRVLIEIFT 136 Query: 134 SRTNQELQEINRVYKEMYK----TDLEKDIISD----TSGDFRKLMVALAKGRRAED--- 182 + N E++ + YK++ K + E+ +++D T GD+ +++L + R + Sbjct: 137 TLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKETCGDYEYALLSLVQAERDDIPIL 196 Query: 183 ----------GSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERY 232 S+I++EL + DA++LY +G R GT + ++ R+ L E Y Sbjct: 197 QLKAIPDKGVNSIINHELAEADAKDLYASGAGRVGTSERRITRVICNRTPYQLYLTSEIY 256 Query: 233 KSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIM 292 +LE I+ E GD + +++ ++P A+ L+DSM G GT+D L+R++ Sbjct: 257 FKMYGKTLLEHIESETSGDYRKLLVAVLRYAIDRPSLIAEWLHDSMAGLGTKDYALMRLL 316 Query: 293 VSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCG 336 ++RSE+D+ I ++ YGKSL ++ DT GDY++ L L G Sbjct: 317 ITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSGDYRRTLCVLMG 360 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 66/256 (25%), Positives = 114/256 (44%), Gaps = 44/256 (17%) Query: 45 AVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQR--------RTKKELPSALKSALSGHLE 96 A+K G ++ ++ I T N + + +A AY++ +++ L + +K G E Sbjct: 120 AMKGLGTNDRVLIEIFTTLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKETCGDYE 179 Query: 97 TVILGLLKTP-------------------------AQYDASELKASMKG-LGTDEDSLIE 130 +L L++ A+ DA +L AS G +GT E + Sbjct: 180 YALLSLVQAERDDIPILQLKAIPDKGVNSIINHELAEADAKDLYASGAGRVGTSERRITR 239 Query: 131 IICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYEL 190 +IC+RT +L + +Y +MY L + I S+TSGD+RKL+VA+ R A D + E Sbjct: 240 VICNRTPYQLYLTSEIYFKMYGKTLLEHIESETSGDYRKLLVAVL--RYAIDRPSLIAEW 297 Query: 191 IDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKG 250 + AG+ GT + ++ RS LQ + + Y+S +L ++K + G Sbjct: 298 LHDSM-----AGL---GTKDYALMRLLITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSG 349 Query: 251 DLENAFLNLVQCIQNK 266 D L+ I N+ Sbjct: 350 DYRRTLCVLMGEIYNQ 365 >1YCN-A nrPDB Length = 317 Score = 153 bits (386), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 101/306 (33%), Positives = 162/306 (52%), Gaps = 9/306 (2%) Query: 38 DALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLET 97 DA + TA + G +E I++IL +RS QR+ I AY ++L L LS E Sbjct: 16 DAEQLRTAFEGWGTNEDLIISILAHRSAEQRKVIRQAYHETYGEDLLKTLDKELSNDFER 75 Query: 98 VILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEK 157 IL P + DA + K + L+E+ C+RT+ +L + Y YK LE+ Sbjct: 76 AILLWTLEPGERDALLANEATKRWTSSNQVLMEVACTRTSTQLLHARQAYHARYKKSLEE 135 Query: 158 DIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIM 217 D+ T+GDFRKL+V+L R E G ++ L Q+A+ +++ +K K + I I+ Sbjct: 136 DVAHHTTGDFRKLLVSLVTSYRYE-GDEVNMTLAKQEAKLVHEK-IKDKHYNDEDVIRIL 193 Query: 218 TERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNL----VQCIQNKPLYFADR 273 + RS + F RY+ ++L+S++ +GD ++ FL L +QC+ LYF D Sbjct: 194 STRSKAQINATFNRYQDDHGEEILKSLE---EGDDDDKFLALLRSTIQCLTRPELYFVDV 250 Query: 274 LYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLY 333 L ++ GT + L RI+ +R+E+D+ I E++R+ L I +DT+GDY+K L+ Sbjct: 251 LRSAINKTGTDEGALTRIVTTRAEIDLKVIGEEYQRRNSIPLEKAITKDTRGDYEKMLVA 310 Query: 334 LCGGDD 339 L G DD Sbjct: 311 LLGEDD 316 Score = 36.6 bits (83), Expect = 0.016, Method: Compositional matrix adjust. Identities = 49/237 (20%), Positives = 99/237 (41%), Gaps = 20/237 (8%) Query: 35 AERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGH 94 ERDAL A K ++ + R++ Q AY R KK L + +G Sbjct: 85 GERDALLANEATKRWTSSNQVLMEVACTRTSTQLLHARQAYHARYKKSLEEDVAHHTTGD 144 Query: 95 LETVILGLLK-----------TPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEI 143 +++ L+ T A+ +A + +K +++ +I I+ +R+ ++ Sbjct: 145 FRKLLVSLVTSYRYEGDEVNMTLAKQEAKLVHEKIKDKHYNDEDVIRILSTRSKAQINAT 204 Query: 144 NRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGV 203 Y++ + ++ K + GD +AL R+ + EL D + + + Sbjct: 205 FNRYQDDHGEEILKSL---EEGDDDDKFLALL---RSTIQCLTRPELYFVD---VLRSAI 255 Query: 204 KRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLV 260 + GTD I+T R+ L+ + E Y+ + + ++I K+ +GD E + L+ Sbjct: 256 NKTGTDEGALTRIVTTRAEIDLKVIGEEYQRRNSIPLEKAITKDTRGDYEKMLVALL 312 >3BRX-A nrPDB Length = 317 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 93/312 (29%), Positives = 147/312 (47%), Gaps = 10/312 (3%) Query: 29 PYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALK 88 P T D + A G +E I++IL +R+ QR I Y ++L AL Sbjct: 8 PTTVPSVSEDCEQLRKAFSGWGTNEGLIIDILGHRNAEQRNLIRKTYAETYGEDLLKALD 67 Query: 89 SALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYK 148 LS E ++L PA+ DA + K + L+EI C+R+ +L + Y Sbjct: 68 KELSNDFERLVLLWALDPAERDALLANEATKRWTSSNQVLMEIACTRSANQLLHARQAYH 127 Query: 149 EMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGT 208 YK LE+D+ T+GDF KL++ L R E G ++ L +A+ L++ + K Sbjct: 128 ARYKKSLEEDVAHHTTGDFHKLLLPLVSSYRYE-GEEVNMTLAKTEAKLLHEK-ISNKAY 185 Query: 209 DVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNL----VQCIQ 264 I ++ RS + YK+ D I K++K D ++ FL L V+C+ Sbjct: 186 SDDDVIRVLATRSKAQINATLNHYKNEYGND----INKDLKADPKDEFLALLRSTVKCLV 241 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 YF L ++ +GT + L R++ +R+EVD+ I E++R+ L I +DT Sbjct: 242 YPEKYFEKVLRLAINRRGTDEGALTRVVCTRAEVDLKVIADEYQRRNSVPLTRAIVKDTH 301 Query: 325 GDYQKALLYLCG 336 GDY+K LL L G Sbjct: 302 GDYEKLLLVLAG 313 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 54/242 (22%), Positives = 98/242 (40%), Gaps = 21/242 (8%) Query: 35 AERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGH 94 AERDAL A K ++ I RS Q AY R KK L + +G Sbjct: 86 AERDALLANEATKRWTSSNQVLMEIACTRSANQLLHARQAYHARYKKSLEEDVAHHTTGD 145 Query: 95 LETVILGLLK-----------TPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEI 143 ++L L+ T A+ +A L + +D +I ++ +R+ ++ Sbjct: 146 FHKLLLPLVSSYRYEGEEVNMTLAKTEAKLLHEKISNKAYSDDDVIRVLATRSKAQINAT 205 Query: 144 NRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGV 203 YK Y D+ KD+ +D +F L+ + K + Y ++ ++ + Sbjct: 206 LNHYKNEYGNDINKDLKADPKDEFLALLRSTVK--------CLVYP--EKYFEKVLRLAI 255 Query: 204 KRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCI 263 R+GTD ++ R+ L+ + + Y+ + + +I K+ GD E L L + Sbjct: 256 NRRGTDEGALTRVVCTRAEVDLKVIADEYQRRNSVPLTRAIVKDTHGDYEKLLLVLAGHV 315 Query: 264 QN 265 +N Sbjct: 316 EN 317 >1DK5-A nrPDB Length = 322 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 88/306 (28%), Positives = 148/306 (48%), Gaps = 6/306 (1%) Query: 35 AERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGH 94 A D + +A K G +E I++IL +R+ QR+ I Y ++L L L+ Sbjct: 21 AAEDCEQLRSAFKGWGTNEKLIISILAHRTAAQRKLIRQTYAETFGEDLLKELDRELTHD 80 Query: 95 LETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTD 154 E ++L P++ DA K + K L+E+ C+R+ +EL Y YK Sbjct: 81 FEKLVLVWTLDPSERDAHLAKEATKRWTKSNFVLVELACTRSPKELVLAREAYHARYKKS 140 Query: 155 LEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWI 214 LE+D+ T+GD RKL+V L R G +D L +++ L++ + K + I Sbjct: 141 LEEDVAYHTTGDHRKLLVPLVSSYRY-GGEEVDLRLAKAESKILHE-KISDKAYSDDEVI 198 Query: 215 SIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLN-LVQCIQNKPLYFADR 273 I+ RS L YK D+L+ ++ GD A L ++ + YF + Sbjct: 199 RILATRSKAQLNATLNHYKDEHGEDILKQLE---DGDEFVALLRATIKGLVYPEHYFVEV 255 Query: 274 LYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLY 333 L D++ +GT + L R++ +R+EVD+ I E++++ L I +DT+GDY+ LL Sbjct: 256 LRDAINRRGTEEDHLTRVIATRAEVDLKIIADEYQKRDSIPLGRAIAKDTRGDYESMLLA 315 Query: 334 LCGGDD 339 L G ++ Sbjct: 316 LLGQEE 321 >1BO9-A nrPDB Length = 73 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 37/72 (51%), Positives = 46/72 (63%) Query: 33 FDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALS 92 F+ D + A+ KGVDE TI++ILT R+N QRQ I AY + T K L LK AL+ Sbjct: 2 FNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALT 61 Query: 93 GHLETVILGLLK 104 GHLE V+L LLK Sbjct: 62 GHLEEVVLALLK 73 Score = 31.6 bits (70), Expect = 0.54, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 35/67 (52%) Query: 110 DASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRK 169 D + L ++ G DE ++I+I+ R N + Q+I Y + L++ + +G + Sbjct: 7 DVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEE 66 Query: 170 LMVALAK 176 +++AL K Sbjct: 67 VVLALLK 73 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 194 DARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLE 253 D L+ A + KG D I I+T+R+ Q++ Y + + E++KK + G LE Sbjct: 7 DVAALHKA-IMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 65 Query: 254 NAFLNLVQ 261 L L++ Sbjct: 66 EVVLALLK 73 >3CHK-A nrPDB Length = 337 Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 67/275 (24%), Positives = 123/275 (44%), Gaps = 21/275 (7%) Query: 65 NVQRQDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTD 124 N+QR +Q T L + LK LS E+++L L K AQ ++ + KG GTD Sbjct: 46 NMQR-----TFQAITGTFLDAFLKKHLSKDFESLVLMLYKPRAQLLCELIRGATKGAGTD 100 Query: 125 EDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGD---FRKLMVALAKGRR-A 180 E L++++ + E++EI ++Y ++Y L D++ GD + KL+ A+A G R Sbjct: 101 EKCLVDVLLTIETHEVREIRQLYYQLYNDSL-GDVVRKDCGDKYMWAKLINAVATGDRIP 159 Query: 181 EDGSVIDYELIDQDARELYDAGVKRKGT---DVPKWISIMTERSVCHLQKVFERYKS-YS 236 D ++ +L+ L ++ KG +V WI I + +++ + Y + Y+ Sbjct: 160 RDTHELEEDLV------LVRKAIETKGVKKDEVSTWIRIFATYTRADFRQLHKMYSAKYN 213 Query: 237 PYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRS 296 + ++ E +G E AF + + A + + G G+ L RI Sbjct: 214 GDSLRAGVEDEFQGLDEYAFKLAHDFLYDPCCAAAFSMNVAFAGSGSDSNRLNRITAMHF 273 Query: 297 EVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKAL 331 + + +K+ YG++ + KG Y A+ Sbjct: 274 R-ECKGCKYYYKKVYGQAFDERCATELKGVYGDAI 307 >4EVF-A nrPDB Length = 295 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 2/113 (1%) Query: 52 DEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSAL-SGHLETVILGLLKTPAQYD 110 DEV I I + S R+ IA AY KELP +K AL G E++++ L + Sbjct: 19 DEVQIAFIASEYSAESREKIAKAYVASYGKELPDDIKKALKGGSEESLLMDLFSDRHEVR 78 Query: 111 ASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDT 163 A ++ ++ G D + + + T ++ E Y M+K L +D + D Sbjct: 79 AQHIRDALSGR-NDHMAFFDTVILCTPEDWHETVAAYTRMFKKPLVEDFMKDV 130 >5TCU-S1 nrPDB Length = 80 Score = 32.0 bits (71), Expect = 0.38, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 1/47 (2%) Query: 187 DYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYK 233 D+ +IDQ A ++ + KR G DV I + TE+SV + + +YK Sbjct: 9 DHRVIDQSAEKIVETA-KRSGADVSGPIPLPTEKSVYTIIRAVHKYK 54 >1Y8N-A nrPDB Length = 419 Score = 31.6 bits (70), Expect = 0.48, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 1/63 (1%) Query: 107 AQYDASELKA-SMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSG 165 A+Y +LK SM+G+GTD ++ + S + + L N+ YKT E D S+ S Sbjct: 348 ARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSS 407 Query: 166 DFR 168 + R Sbjct: 408 EPR 410 >5ND9-j nrPDB Length = 102 Score = 31.2 bits (69), Expect = 0.62, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 187 DYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYK 233 D+ +IDQ A ++ + KR G DV I + TE+SV + + YK Sbjct: 14 DHRVIDQSAEKIVETA-KRSGADVSGPIPLPTEKSVYTIIRAVHMYK 59 >5T7V-S1 nrPDB Length = 82 Score = 31.2 bits (69), Expect = 0.70, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 187 DYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYK 233 D+ +IDQ A ++ + KR G DV I + TE+SV + + YK Sbjct: 2 DHRVIDQSAEKIVETA-KRSGADVSGPIPLPTEKSVYTIIRAVHGYK 47 >2JLW-A nrPDB Length = 451 Score = 30.8 bits (68), Expect = 0.81, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 28/44 (63%), Gaps = 4/44 (9%) Query: 78 RTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGL 121 +TK+ LPS ++ AL L T+IL P + A+E++ +++GL Sbjct: 32 KTKRILPSIVREALKRRLRTLILA----PTRVVAAEMEEALRGL 71 >5HH5-A nrPDB Length = 271 Score = 30.8 bits (68), Expect = 0.95, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 8/70 (11%) Query: 270 FADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQK 329 A L D+MK +G + L I++S + D +E KR+ G + + + Sbjct: 61 MASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKV--------AANAES 112 Query: 330 ALLYLCGGDD 339 A+L GG D Sbjct: 113 AVLLARGGSD 122 >2WZQ-A nrPDB Length = 619 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 28/44 (63%), Gaps = 4/44 (9%) Query: 78 RTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGL 121 +TK+ LPS ++ AL L T+IL P + A+E++ +++GL Sbjct: 200 KTKRILPSIVREALKRRLRTLIL----APTRVVAAEMEEALRGL 239 >3ES8-A nrPDB Length = 391 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 8/52 (15%) Query: 267 PLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYY 318 PLY D L+D +G L+ I++ ++ D++KI E + +++YYY Sbjct: 47 PLYSVD-LHDLKQG-------LLSILLGQNPFDLMKINKELTDNFPETMYYY 90 >2Z83-A nrPDB Length = 459 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 16/81 (19%) Query: 78 RTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGT-----------DED 126 +T+K LP +K A+ L T +L P + A+E+ +++GL + Sbjct: 34 KTRKILPQIIKDAIQQRLRTAVL----APTRVVAAEMAEALRGLPVRYQTSAVQREHQGN 89 Query: 127 SLIEIICSRT-NQELQEINRV 146 +++++C T L NRV Sbjct: 90 EIVDVMCHATLTHRLMSPNRV 110 >5NJT-J nrPDB Length = 102 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 187 DYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYK 233 D+ ++DQ A ++ + KR G V I + TE+SV + + +YK Sbjct: 14 DHRILDQSAEKIVETA-KRSGASVSGPIPLPTEKSVYTILRAVHKYK 59 >5K8T-A nrPDB Length = 458 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 27/44 (61%), Gaps = 4/44 (9%) Query: 78 RTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGL 121 +T++ LP ++ A+ L TVIL P + A+E++ +++GL Sbjct: 37 KTRRVLPEIVREAIKTRLRTVILA----PTRVVAAEMEEALRGL 76 >4KKJ-A nrPDB Length = 467 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 24/38 (63%), Gaps = 1/38 (2%) Query: 157 KDIISD-TSGDFRKLMVALAKGRRAEDGSVIDYELIDQ 193 K +SD +SG+ +++AL R AE+ + DY LID+ Sbjct: 84 KSRLSDVSSGELALIILALGVCRNAEENLIYDYHLIDK 121 >2BMF-A nrPDB Length = 451 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 28/44 (63%), Gaps = 4/44 (9%) Query: 78 RTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGL 121 +TK+ LP+ ++ A+ L T+IL P + A+E++ +++GL Sbjct: 32 KTKRYLPAIVREAIKRGLRTLILA----PTRVVAAEMEEALRGL 71 >5UM7-A nrPDB Length = 187 Score = 28.1 bits (61), Expect = 5.8, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 17/90 (18%) Query: 176 KGRRAEDGS-----------VIDYELIDQDARELYDAGVKRKGTDVPKWISIMT--ERSV 222 KG +DGS + ++E++DQ + A K V +W S ++ + Sbjct: 34 KGSTQKDGSSAVEHELTGQQLPEFEMVDQAGYQKKSAEFYNKPMLVVEWASWCPDCQKQL 93 Query: 223 CHLQKVFERYKS---YSPYDMLESIKKEVK 249 +QKV+E+YK + DML+S K+E K Sbjct: 94 PEIQKVYEKYKGKIHFVMLDMLDS-KRETK 122 >4N5C-A nrPDB Length = 802 Score = 27.3 bits (59), Expect = 8.9, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 10/72 (13%) Query: 73 FAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEII 132 ++Y ++ + +A+K+ LE++IL K P Y A L A + + D++ +I+ Sbjct: 492 YSYTLAQQRHIETAIKT-----LESLILS--KNPNYYKAWHLLALCRSVQEDKEMSYKIV 544 Query: 133 CS---RTNQELQ 141 CS N+ LQ Sbjct: 545 CSVLEAMNESLQ 556 >6AHD-N nrPDB Length = 941 Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 15/96 (15%) Query: 166 DFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKW--ISIMTER--S 221 DF KL + KG+ E +++ ARE Y+ G+K+ P W +S + E+ Sbjct: 707 DFPKLW--MMKGQIEEQKEMME------KAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQ 758 Query: 222 VCHLQKVFERYKSYSPYD---MLESIKKEVKGDLEN 254 + + + E+ + +P + LES++ E + L+N Sbjct: 759 LTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKN 794 >2C5U-A nrPDB Length = 375 Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 167 FRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWI 214 ++++ + L R E G I Y+ I +DA L V+R D PKWI Sbjct: 172 YQEMKIILLNVRENETGEYISYDDIYKDAT-LRPYLVERYEIDSPKWI 218 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4X9P-A nrPDB 483 e-137 5N7D-A nrPDB 457 e-129 2ZHI-A nrPDB 448 e-126 2ZOC-A nrPDB 440 e-124 1I4A-A nrPDB 438 e-123 1YII-A nrPDB 435 e-122 1SAV-A nrPDB 430 e-121 2IE7-A nrPDB 427 e-120 1AVC-A nrPDB 427 e-120 1HM6-A nrPDB 424 e-119 1AII-A nrPDB 423 e-119 1M9I-A nrPDB 422 e-118 1W3W-A nrPDB 419 e-118 1AIN-A nrPDB 417 e-117 1DM5-A nrPDB 397 e-111 6B3I-A nrPDB 386 e-108 4MDV-A nrPDB 367 e-102 3BRX-A nrPDB 349 8e-97 1YCN-A nrPDB 344 4e-95 1DK5-A nrPDB 336 5e-93 3CHK-A nrPDB 250 7e-67 4EVF-A nrPDB 128 3e-30 1BO9-A nrPDB 100 1e-21 Sequences not found previously or not previously below threshold: 2IIC-A nrPDB 63 1e-10 1IHU-A nrPDB 35 0.062 5V8F-D nrPDB 32 0.36 3OCE-A nrPDB 31 0.90 3DO5-A nrPDB 30 1.5 2ZQJ-A nrPDB 30 2.2 3IYJ-F nrPDB 29 3.8 3AMU-A nrPDB 28 4.0 3AU7-A nrPDB 28 4.1 4WXH-A nrPDB 28 5.9 6CNF-S nrPDB 28 7.2 6F41-W nrPDB 28 7.6 2J41-A nrPDB 28 7.6 2EJ9-A nrPDB 28 8.6 >4X9P-A nrPDB Length = 343 Score = 483 bits (1243), Expect = e-137, Method: Composition-based stats. Identities = 332/339 (97%), Positives = 336/339 (99%) Query: 1 MSTVHEILCKLSLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNIL 60 MSTVHEILCKLSLEGDHSTPPSAYGSVK YTNFDAERDALNIETA+KTKGVDEVTIVNIL Sbjct: 5 MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNIL 64 Query: 61 TNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKG 120 TNRSN QRQDIAFAYQRRTKKEL SALKSALSGHLETVILGLLKTPAQYDASELKASMKG Sbjct: 65 TNRSNEQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKG 124 Query: 121 LGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRA 180 LGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDI+SDTSGDFRKLMVALAKGRRA Sbjct: 125 LGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIVSDTSGDFRKLMVALAKGRRA 184 Query: 181 EDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDM 240 EDGSVIDYELIDQDAR+LYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDM Sbjct: 185 EDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDM 244 Query: 241 LESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDM 300 LESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDM Sbjct: 245 LESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDM 304 Query: 301 LKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 339 LKIRSEFK+KYGKSLYYYIQQDTKGDYQKALLYLCGGDD Sbjct: 305 LKIRSEFKKKYGKSLYYYIQQDTKGDYQKALLYLCGGDD 343 >5N7D-A nrPDB Length = 427 Score = 457 bits (1176), Expect = e-129, Method: Composition-based stats. Identities = 310/319 (97%), Positives = 314/319 (98%) Query: 21 PSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTK 80 SAYGSVK YTNFDAERDALNIETA+KTKGVDEVTIVNILTNRSN QRQDIAFAYQRRTK Sbjct: 109 SSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNEQRQDIAFAYQRRTK 168 Query: 81 KELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQEL 140 KEL SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQEL Sbjct: 169 KELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQEL 228 Query: 141 QEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYD 200 QEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAR+LYD Sbjct: 229 QEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYD 288 Query: 201 AGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLV 260 AGVKRKGTDVPKWISIMTERSV HLQKVF+RYKSYSPYDMLESI+KEVKGDLENAFLNLV Sbjct: 289 AGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLV 348 Query: 261 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 320 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ Sbjct: 349 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 408 Query: 321 QDTKGDYQKALLYLCGGDD 339 QDTKGDYQKALLYLCGGDD Sbjct: 409 QDTKGDYQKALLYLCGGDD 427 >2ZHI-A nrPDB Length = 322 Score = 448 bits (1152), Expect = e-126, Method: Composition-based stats. Identities = 158/315 (50%), Positives = 214/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+VK + F+A DA + A+K G DE I+ +L R+ QRQ+I AY+ ++L Sbjct: 9 GTVKAASGFNATEDAQVLRKAMKGLGTDEDAIIGVLACRNTAQRQEIRTAYKSTIGRDLL 68 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS LS + E VILG++ YD EL+ +MKG GTDE LIEI+ SR +E++ IN Sbjct: 69 EDLKSELSSNFEQVILGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRNPEEIRRIN 128 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y++ Y LE+DI SDTS F++++V+L G R E G+ +D L+ QDA++LY+AG K Sbjct: 129 QTYQQQYGRSLEEDICSDTSFMFQRVLVSLTAGGRDE-GNYLDDALVKQDAQDLYEAGEK 187 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 R GTD K++SI+ R+ HL VF+ YK S D+ +SIK E G E+A L +V+C++ Sbjct: 188 RWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMR 247 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 NKP YFA+RLY SMKG GT D LIR+MVSR+E+DML IR+ FKR YGKSLY +I+ DT Sbjct: 248 NKPAYFAERLYKSMKGLGTDDSTLIRVMVSRAEIDMLDIRANFKRLYGKSLYSFIKGDTS 307 Query: 325 GDYQKALLYLCGGDD 339 GDY+K LL LCGGDD Sbjct: 308 GDYRKVLLILCGGDD 322 >2ZOC-A nrPDB Length = 319 Score = 440 bits (1133), Expect = e-124, Method: Composition-based stats. Identities = 153/315 (48%), Positives = 216/315 (68%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+VK + F+A DA + A+K G DE I+++L R+ QRQ+I AY+ ++L Sbjct: 6 GTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLI 65 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS LSG+ E VI+G++ YD EL+ +MKG GTDE LIEI+ SRT +E++ I+ Sbjct: 66 DDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRIS 125 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y++ Y LE DI SDTS F++++V+L+ G R E G+ +D L+ QDA++LY+AG K Sbjct: 126 QTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDE-GNYLDDALVRQDAQDLYEAGEK 184 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+++++ R+ HL VF+ YK S D+ +SIK E G E+A L +V+C++ Sbjct: 185 KWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMR 244 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 NK YFA++LY SMKG GT D LIR+MVSR+E+DML IR+ FKR YGKSLY +I+ DT Sbjct: 245 NKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTS 304 Query: 325 GDYQKALLYLCGGDD 339 GDY+K LL LCGGDD Sbjct: 305 GDYRKVLLVLCGGDD 319 >1I4A-A nrPDB Length = 318 Score = 438 bits (1126), Expect = e-123, Method: Composition-based stats. Identities = 156/315 (49%), Positives = 213/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G VK + F+A DA + A+K G DE I+N+L RS QRQ+I AY+ ++L Sbjct: 5 GDVKAASGFNAAEDAQTLRKAMKGLGTDEDAIINVLAYRSTAQRQEIRTAYKTTIGRDLM 64 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS LSG+ E VILG++ YD EL+ +MKG GTDE LIEI+ SRT +E++ IN Sbjct: 65 DDLKSELSGNFEQVILGMMTPTVLYDVQELRKAMKGAGTDEGCLIEILASRTPEEIRRIN 124 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y+ Y LE DI SDTS F++++V+L+ G R E + +D L+ QDA++LY+AG K Sbjct: 125 QTYQLQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDE-SNYLDDALMRQDAQDLYEAGEK 183 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+++++ R+ HL VF+ YK + D+ +SIK E G E+A L +V+C++ Sbjct: 184 KWGTDEVKFLTVLCSRNRNHLLHVFDEYKRIAQKDIEQSIKSETSGSFEDALLAIVKCMR 243 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 NK YFA+RLY SMKG GT D LIR+MVSR+E+DML IR+ FKR YGKSLY +I+ DT Sbjct: 244 NKSAYFAERLYKSMKGLGTDDDTLIRVMVSRAEIDMLDIRANFKRLYGKSLYSFIKGDTS 303 Query: 325 GDYQKALLYLCGGDD 339 GDY+K LL LCGGDD Sbjct: 304 GDYRKVLLILCGGDD 318 >1YII-A nrPDB Length = 320 Score = 435 bits (1120), Expect = e-122, Method: Composition-based stats. Identities = 149/315 (47%), Positives = 215/315 (68%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V ++ FDA DA + A+K G DE TI+ ILT+R+N QRQ+IA A++ ++L Sbjct: 6 GTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLV 65 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS L+G ET+++ L++ +DA LK ++KG GT+E L EI+ SRT E+Q I Sbjct: 66 DDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIK 125 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 +VY + Y+ +LE I +TSG F++L+V L + R DG +D L+++DA+ L+ AG Sbjct: 126 QVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGR-VDEALVEKDAQVLFRAGEL 184 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD +I+I+ RSV HL++VF++Y + S + + E+I +E GDLE L +V+CI+ Sbjct: 185 KWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIR 244 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P YFA+ LY SMKG GT D LIR+MVSRSE+D+L IR EF++ + KSLY IQ+DT Sbjct: 245 SVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTS 304 Query: 325 GDYQKALLYLCGGDD 339 GDY+KALL LCGGDD Sbjct: 305 GDYRKALLLLCGGDD 319 >1SAV-A nrPDB Length = 320 Score = 430 bits (1106), Expect = e-121, Method: Composition-based stats. Identities = 144/315 (45%), Positives = 208/315 (66%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V + FD DA + A+K G DE +I+ +LT+RSN QRQ+I+ A++ ++L Sbjct: 7 GTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLL 66 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LKS L+G E +I+ L+K YDA ELK ++KG GT+E L EII SRT +EL+ I Sbjct: 67 DDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIK 126 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 +VY+E Y + LE D++ DTSG +++++V L + R D ID ++QDA+ L+ AG Sbjct: 127 QVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAG-IDEAQVEQDAQALFQAGEL 185 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+I+I RSV HL+KVF++Y + S + + E+I +E G+LE L +V+ I+ Sbjct: 186 KWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIR 245 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P Y A+ LY +MKG GT D LIR+MVSRSE+D+ IR EF++ + SLY I+ DT Sbjct: 246 SIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTS 305 Query: 325 GDYQKALLYLCGGDD 339 GDY+KALL LCG DD Sbjct: 306 GDYKKALLLLCGEDD 320 >2IE7-A nrPDB Length = 318 Score = 427 bits (1099), Expect = e-120, Method: Composition-based stats. Identities = 142/315 (45%), Positives = 211/315 (66%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V ++ FD DA + A+K G DE +I+N+LT RSN QRQ IA ++ ++L Sbjct: 4 GTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLV 63 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + +KS L+G E +I+ L+K YDA ELK ++KG GTDE L EII SRT +EL+ I Sbjct: 64 NDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIK 123 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y+E Y ++LE D++ DTSG +++++V L + R D + ID ++ DA+ L+ AG Sbjct: 124 QAYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTA-IDDAQVELDAQALFQAGEL 182 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD K+I+I+ RSV HL++VF++Y + S + + E+I +E G+LEN L +V+ I+ Sbjct: 183 KWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIR 242 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P Y A+ LY +MKG GT D LIR++VSRSE+D+ IR EF++ + SLY I+ DT Sbjct: 243 SIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTS 302 Query: 325 GDYQKALLYLCGGDD 339 GDY+KALL LCGG+D Sbjct: 303 GDYKKALLLLCGGED 317 Score = 95.4 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 44/147 (29%), Positives = 74/147 (50%), Gaps = 4/147 (2%) Query: 38 DALNIETAVK-TKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLE 96 DA + A + G DE + IL RS + + Y + ++ + SG+LE Sbjct: 172 DAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLE 231 Query: 97 TVILGLLKTP---AQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKT 153 ++L ++K+ Y A L +MKG GTD+ +LI +I SR+ +L I + +++ + T Sbjct: 232 NLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFAT 291 Query: 154 DLEKDIISDTSGDFRKLMVALAKGRRA 180 L I DTSGD++K ++ L G Sbjct: 292 SLYSMIKGDTSGDYKKALLLLCGGEDD 318 >1AVC-A nrPDB Length = 673 Score = 427 bits (1097), Expect = e-120, Method: Composition-based stats. Identities = 148/315 (46%), Positives = 213/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 GS++ + +F+ +DA + A+K G D+ I+N++T+RSN QRQ+I Y+ K+L Sbjct: 12 GSIRDFPDFNPSQDAETLYNAMKGFGSDKEAIINLITSRSNKQRQEICQNYKSLYGKDLI 71 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++ Sbjct: 72 ADLKYELTGKFERLIVGLMRPPAYADAKEIKDAISGIGTDEKCLIEILASRTNEQIHQLV 131 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 YK+ Y+ DLE DI DTSG FRK++V L +G R ED V+ +L+ QD ++LY+AG Sbjct: 132 AAYKDAYERDLEADITGDTSGHFRKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 190 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD ++I I+ RS HL+ VF+ Y + + SI+ E+ GD E L +V+CI+ Sbjct: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT Sbjct: 251 STAEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310 Query: 325 GDYQKALLYLCGGDD 339 G+Y+K LL LCGGDD Sbjct: 311 GEYKKTLLKLCGGDD 325 Score = 398 bits (1023), Expect = e-111, Method: Composition-based stats. Identities = 148/321 (46%), Positives = 213/321 (66%), Gaps = 8/321 (2%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V+P +F+ + DA + A+K G DE TI++I+T+RSN QRQ I ++ ++L Sbjct: 355 GTVRPAGDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNAQRQQIRQTFKSHFGRDLM 414 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LKS LSG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E+Q IN Sbjct: 415 ADLKSELSGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIQAIN 474 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAR------EL 198 + YKE Y LE + SDTSG F++++++LA G R E G D E +DA+ E+ Sbjct: 475 KAYKEDYHKTLEDALSSDTSGHFKRILISLATGNREEGGE--DRERAREDAQVAAEILEI 532 Query: 199 YDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLN 258 D K + +++ I+ RS L++VF+ + + YD+ +IKKE+ GD+ + F+ Sbjct: 533 ADTTSGDKSSLETRFMMILCTRSYPDLRRVFQEFVKMTNYDVEHTIKKEMSGDVRDVFVA 592 Query: 259 LVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYY 318 +VQ ++NKPL+FAD+LY SMKG GT +K L RIMVSRSE+D+L IR EF KY KSL+ Sbjct: 593 IVQSVKNKPLFFADKLYKSMKGAGTEEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652 Query: 319 IQQDTKGDYQKALLYLCGGDD 339 I+ DT G + KALL +CGG+D Sbjct: 653 IEGDTSGHFLKALLAICGGED 673 Score = 192 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 93/336 (27%), Positives = 162/336 (48%), Gaps = 36/336 (10%) Query: 35 AERDALNIETAVK-TKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSG 93 ++D ++ A + G DE + IL NRS + + Y + T K + ++++ LSG Sbjct: 177 VQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSG 236 Query: 94 HLETVILGLLK---TPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEM 150 E ++L ++K + A+Y A L +MKGLGT +++LI I+ SR+ ++ +I +++ Sbjct: 237 DFEKLMLAVVKCIRSTAEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTK 296 Query: 151 YKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELI------------------- 191 Y+ L I +DTSG+++K ++ L G G Sbjct: 297 YEKSLYSMIKNDTSGEYKKTLLKLCGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGT 356 Query: 192 ---------DQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLE 242 D DA+ L +K GTD I I+T RS Q++ + +KS+ D++ Sbjct: 357 VRPAGDFNPDADAKAL-RKAMKGLGTDEDTIIDIITHRSNAQRQQIRQTFKSHFGRDLMA 415 Query: 243 SIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLK 302 +K E+ GDL L L + Y A +L +M+G GT +K LI I+ +R+ ++ Sbjct: 416 DLKSELSGDLARLILGL---MMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIQA 472 Query: 303 IRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGGD 338 I +K Y K+L + DT G +++ L+ L G+ Sbjct: 473 INKAYKEDYHKTLEDALSSDTSGHFKRILISLATGN 508 >1HM6-A nrPDB Length = 346 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 177/327 (54%), Positives = 237/327 (72%), Gaps = 4/327 (1%) Query: 12 SLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDI 71 +++G P SA V PY F+ D + A+ KGVDE TI+ ILT R+N QRQ I Sbjct: 24 TVKGSKGGPGSA---VSPYPTFNPSSDVEALHKAITVKGVDEATIIEILTKRTNAQRQQI 80 Query: 72 AFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEI 131 AY + K L ALK AL+GHLE V L LLKTPAQ+DA EL+A+MKGLGTDED+L EI Sbjct: 81 KAAYLQEKGKPLDEALKKALTGHLEEVALALLKTPAQFDADELRAAMKGLGTDEDTLNEI 140 Query: 132 ICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELI 191 + SRTN+E++EINRVYKE K DL KDI SDTSGD++K +++LAKG R+ED + I+ +L Sbjct: 141 LASRTNREIREINRVYKEELKRDLAKDITSDTSGDYQKALLSLAKGDRSEDLA-INDDLA 199 Query: 192 DQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGD 251 D DAR LY+AG +RKGTD+ +I+I+T RS HL++VF++Y YS +DM + + E+KGD Sbjct: 200 DTDARALYEAGERRKGTDLNVFITILTTRSYPHLRRVFQKYSKYSKHDMNKVLDLELKGD 259 Query: 252 LENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKY 311 +EN +V+C +KP++FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ Y Sbjct: 260 IENCLTVVVKCATSKPMFFAEKLHQAMKGIGTRHKTLIRIMVSRSEIDMNDIKACYQKLY 319 Query: 312 GKSLYYYIQQDTKGDYQKALLYLCGGD 338 G SL I +TKGDY+K L+ LCGGD Sbjct: 320 GISLCQAILDETKGDYEKILVALCGGD 346 >1AII-A nrPDB Length = 323 Score = 423 bits (1087), Expect = e-119, Method: Composition-based stats. Identities = 149/315 (47%), Positives = 209/315 (66%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G+V+ Y +F DA I+ A++ G DE +++ILT RSN QRQ I YQ KEL Sbjct: 10 GTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELK 69 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 LK LSGH E +++ L+ PA +DA +LK SMKG GT+ED+LIEI+ +RT++++++I+ Sbjct: 70 DDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDIS 129 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 + Y +YK L DI S+TSGDFRK ++ LA GRR E +D L QDA+ LY AG Sbjct: 130 QAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLK-VDEHLAKQDAQILYKAGEN 188 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 R GTD K+ I+ RS L+ F+ Y++ S D+++SIK E+ G E+ L +V C++ Sbjct: 189 RWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVR 248 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 N P + A+RL+ ++KG GT + L RIMVSRSE+D+L IR+EFK+ YG SLY I+ DT Sbjct: 249 NTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTS 308 Query: 325 GDYQKALLYLCGGDD 339 GDY+ LL +CGGDD Sbjct: 309 GDYEITLLKICGGDD 323 >1M9I-A nrPDB Length = 672 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 149/315 (47%), Positives = 214/315 (67%), Gaps = 1/315 (0%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 GS+ + FD +DA + TA+K G D+ I++I+T+RSN QRQ++ +Y+ K+L Sbjct: 11 GSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLI 70 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LK L+G E +I+GL++ PA DA E+K ++ G+GTDE LIEI+ SRTN+++ ++ Sbjct: 71 ADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLV 130 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVK 204 YK+ Y+ DLE DII DTSG F+K++V L +G R ED V+ +L+ QD ++LY+AG Sbjct: 131 AAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREED-DVVSEDLVQQDVQDLYEAGEL 189 Query: 205 RKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQ 264 + GTD ++I I+ RS HL+ VF+ Y + + SI+ E+ GD E L +V+CI+ Sbjct: 190 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 249 Query: 265 NKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTK 324 + P YFA+RL+ +MKG GTRD LIRIMVSRSE+DML IR F+ KY KSLY I+ DT Sbjct: 250 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 309 Query: 325 GDYQKALLYLCGGDD 339 G+Y+K LL L GGDD Sbjct: 310 GEYKKTLLKLSGGDD 324 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 151/319 (47%), Positives = 213/319 (66%), Gaps = 4/319 (1%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELP 84 G V+P +F+ + DA + A+K G DE TI++I+T+RSNVQRQ I ++ ++L Sbjct: 354 GDVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLM 413 Query: 85 SALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEIN 144 + LKS +SG L +ILGL+ PA YDA +LK +M+G GTDE +LIEI+ +RTN E++ IN Sbjct: 414 TDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAIN 473 Query: 145 RVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDAR----ELYD 200 YKE Y LE + SDTSG FR+++++LA G R E G +D D E+ D Sbjct: 474 EAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIAD 533 Query: 201 AGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLV 260 K + ++++I+ RS HL++VF+ + + YD+ +IKKE+ GD+ +AF+ +V Sbjct: 534 TPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 593 Query: 261 QCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQ 320 Q ++NKPL+FAD+LY SMKG GT DK L RIMVSRSE+D+L IR EF KY KSL+ I+ Sbjct: 594 QSVKNKPLFFADKLYKSMKGAGTDDKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIE 653 Query: 321 QDTKGDYQKALLYLCGGDD 339 DT GD+ KALL LCGG+D Sbjct: 654 GDTSGDFLKALLALCGGED 672 Score = 190 bits (484), Expect = 6e-49, Method: Composition-based stats. Identities = 93/335 (27%), Positives = 161/335 (48%), Gaps = 36/335 (10%) Query: 35 AERDALNIETAVK-TKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSG 93 ++D ++ A + G DE + IL NRS + + Y + T K + ++++ LSG Sbjct: 176 VQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSG 235 Query: 94 HLETVILGLLK---TPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEM 150 E ++L ++K + +Y A L +MKGLGT +++LI I+ SR+ ++ +I +++ Sbjct: 236 DFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTK 295 Query: 151 YKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELI------------------- 191 Y+ L I +DTSG+++K ++ L+ G G Sbjct: 296 YEKSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGD 355 Query: 192 ---------DQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLE 242 D DA+ L +K GTD I I+T RS Q++ + +KS+ D++ Sbjct: 356 VRPANDFNPDADAKAL-RKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMT 414 Query: 243 SIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLK 302 +K E+ GDL L L + Y A +L +M+G GT +K LI I+ +R+ ++ Sbjct: 415 DLKSEISGDLARLILGL---MMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRA 471 Query: 303 IRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGG 337 I +K Y KSL + DT G +++ L+ L G Sbjct: 472 INEAYKEDYHKSLEDALSSDTSGHFRRILISLATG 506 >1W3W-A nrPDB Length = 327 Score = 419 bits (1077), Expect = e-118, Method: Composition-based stats. Identities = 146/313 (46%), Positives = 206/313 (65%) Query: 26 SVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPS 85 +VK ++F+ + DA + A+K G +E I+++LT RSN QRQ IA +++ + K+L Sbjct: 14 TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73 Query: 86 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145 LKS LSG E +I+ L+ P +Y+A EL +MKGLGT E +IEI+ SRT +L+EI + Sbjct: 74 TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133 Query: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKR 205 Y+E Y + LE+DI +DTSG +++V L +G R + S +D L QDA++LY AG K Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGEKI 193 Query: 206 KGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQN 265 +GTD K+I+I+ RS HL +VFE Y+ + + +SIK E G LE A L +V+C QN Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253 Query: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 YFA+RLY +MKG GTRD LIR +VSRSE+D+ I+ FK+ YGK+L I +DT G Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313 Query: 326 DYQKALLYLCGGD 338 DY+ ALL L G D Sbjct: 314 DYKNALLSLVGSD 326 >1AIN-A nrPDB Length = 314 Score = 417 bits (1071), Expect = e-117, Method: Composition-based stats. Identities = 169/313 (53%), Positives = 228/313 (72%), Gaps = 1/313 (0%) Query: 26 SVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPS 85 +V PY F+ D + A+ KGVDE TI++ILT R+N QRQ I AY + T K L Sbjct: 3 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 62 Query: 86 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145 LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR Sbjct: 63 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 122 Query: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKR 205 VY+E K DL KDI SDTSGDFR +++LAKG R+ED ++ +L D DAR LY+AG +R Sbjct: 123 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFG-VNEDLADSDARALYEAGERR 181 Query: 206 KGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQN 265 KGTDV + +I+T RS L++VF++Y YS +DM + + E+KGD+E +V+C + Sbjct: 182 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 241 Query: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ YG SL I +TKG Sbjct: 242 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 301 Query: 326 DYQKALLYLCGGD 338 DY+K L+ LCGG+ Sbjct: 302 DYEKILVALCGGN 314 >1DM5-A nrPDB Length = 315 Score = 397 bits (1019), Expect = e-111, Method: Composition-based stats. Identities = 133/313 (42%), Positives = 203/313 (64%), Gaps = 1/313 (0%) Query: 24 YGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKEL 83 G+VKP+ +F++ DA + A+K G DE +I +IL RSN QRQ I Y K L Sbjct: 3 QGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQIKTDYTTLFGKHL 62 Query: 84 PSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEI 143 LKS LSG+ E L LL+ P ++ A +L A+MKGLGTD+++LI+I+C+++N ++ I Sbjct: 63 EDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGLGTDKNALIDILCTQSNAQIHAI 122 Query: 144 NRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGV 203 +K +YK DLEK+IIS+TSG+F++L+V++ +G R ED ++ +DA +Y AG Sbjct: 123 KAAFKLLYKEDLEKEIISETSGNFQRLLVSMLQGGRKEDEP-VNAAHAAEDAAAIYQAGE 181 Query: 204 KRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCI 263 + GTD ++ +++ RS L ++F Y S +L++I+ E GD++N L +V+ + Sbjct: 182 GQIGTDESRFNAVLATRSYPQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSV 241 Query: 264 QNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDT 323 +N+ YFA+RL+ +MKG GT DK LIRI+VSRSE+D+ I+ F+ YGKSLY +I D Sbjct: 242 ENRFAYFAERLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADDC 301 Query: 324 KGDYQKALLYLCG 336 GDY+ LL + G Sbjct: 302 SGDYKDLLLQITG 314 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 41/146 (28%), Positives = 72/146 (49%), Gaps = 4/146 (2%) Query: 192 DQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGD 251 +DA L +K GTD I+ RS Q++ Y + + + +K E+ G+ Sbjct: 15 REDAETL-RKAMKGIGTDEKSITHILATRSNAQRQQIKTDYTTLFGKHLEDELKSELSGN 73 Query: 252 LENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKY 311 E A L L ++ + A++L+ +MKG GT LI I+ ++S + I++ FK Y Sbjct: 74 YEAAALAL---LRKPDEFLAEQLHAAMKGLGTDKNALIDILCTQSNAQIHAIKAAFKLLY 130 Query: 312 GKSLYYYIQQDTKGDYQKALLYLCGG 337 + L I +T G++Q+ L+ + G Sbjct: 131 KEDLEKEIISETSGNFQRLLVSMLQG 156 >6B3I-A nrPDB Length = 343 Score = 386 bits (992), Expect = e-108, Method: Composition-based stats. Identities = 135/325 (41%), Positives = 203/325 (62%), Gaps = 8/325 (2%) Query: 11 LSLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQD 70 + + H+ S G FD +RDA + A K G +E I+ IL+ R++ +RQ Sbjct: 26 MEMGNRHAKASSPQG-------FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQ 78 Query: 71 IAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIE 130 I Y+ KEL LKS LSG+ E L LL P++Y A +L+ +MKGLGTDE LIE Sbjct: 79 IKQKYKATYGKELEEVLKSELSGNFEKTALALLDHPSEYAARQLQKAMKGLGTDESVLIE 138 Query: 131 IICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYEL 190 ++C+RTN+E+ I Y+ ++ LE D+ DTSG+ +K++V+L + R E G +D +L Sbjct: 139 VLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDL 197 Query: 191 IDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKG 250 QDA++LYDAG R GTD + ++ +RS L+ F+ Y+ D+ E+I++E G Sbjct: 198 AGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSG 257 Query: 251 DLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRK 310 DL+ A+L LV+C Q+ YFA+RLY SMKG GT ++ LIRI+V+R+EVD+ I+++F+ K Sbjct: 258 DLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIIVTRAEVDLQGIKAKFQEK 317 Query: 311 YGKSLYYYIQQDTKGDYQKALLYLC 335 Y KSL ++ DT GD++K L+ L Sbjct: 318 YQKSLSDMVRSDTSGDFRKLLVALL 342 >4MDV-A nrPDB Length = 375 Score = 367 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 108/345 (31%), Positives = 177/345 (51%), Gaps = 26/345 (7%) Query: 14 EGDHSTPPSAYGSVKPYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAF 73 G H P ++KP T F A DA + ++K G +E+ I+NIL R+N +RQ+I Sbjct: 22 HGKHYRP-----TIKPTTGFSASADAERLHRSMKGPGTNELAIINILARRTNYERQEICQ 76 Query: 74 AYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIIC 133 +Y+ K++L LKS SG V+ L+ A L +MKGLGT++ LIEI Sbjct: 77 SYKSLYKQDLKDDLKSDTSGDFRKVLCQLIVDTPYMLAKSLYYAMKGLGTNDRVLIEIFT 136 Query: 134 SRTNQELQEINRVYKEMYK--------TDLEKDIISDTSGDFRKLMVALAKGRRAED--- 182 + N E++ + YK++ K L D+ +T GD+ +++L + R + Sbjct: 137 TLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKETCGDYEYALLSLVQAERDDIPIL 196 Query: 183 ----------GSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERY 232 S+I++EL + DA++LY +G R GT + ++ R+ L E Y Sbjct: 197 QLKAIPDKGVNSIINHELAEADAKDLYASGAGRVGTSERRITRVICNRTPYQLYLTSEIY 256 Query: 233 KSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIM 292 +LE I+ E GD + +++ ++P A+ L+DSM G GT+D L+R++ Sbjct: 257 FKMYGKTLLEHIESETSGDYRKLLVAVLRYAIDRPSLIAEWLHDSMAGLGTKDYALMRLL 316 Query: 293 VSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYLCGG 337 ++RSE+D+ I ++ YGKSL ++ DT GDY++ L L G Sbjct: 317 ITRSEIDLQDIMDAYESIYGKSLLNAVKDDTSGDYRRTLCVLMGE 361 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 65/261 (24%), Positives = 112/261 (42%), Gaps = 44/261 (16%) Query: 39 ALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTK--------KELPSALKSA 90 A ++ A+K G ++ ++ I T N + + +A AY++ K + L + +K Sbjct: 114 AKSLYYAMKGLGTNDRVLIEIFTTLWNDEMKAVADAYKQVLKDKGSEESERSLVTDMKKE 173 Query: 91 LSGHLETVILGLLK-------------------------TPAQYDASELKASMKGL-GTD 124 G E +L L++ A+ DA +L AS G GT Sbjct: 174 TCGDYEYALLSLVQAERDDIPILQLKAIPDKGVNSIINHELAEADAKDLYASGAGRVGTS 233 Query: 125 EDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGS 184 E + +IC+RT +L + +Y +MY L + I S+TSGD+RKL+VA+ + Sbjct: 234 ERRITRVICNRTPYQLYLTSEIYFKMYGKTLLEHIESETSGDYRKLLVAVLRYAIDRPSL 293 Query: 185 VIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESI 244 + A L+D+ GT + ++ RS LQ + + Y+S +L ++ Sbjct: 294 I---------AEWLHDSMAG-LGTKDYALMRLLITRSEIDLQDIMDAYESIYGKSLLNAV 343 Query: 245 KKEVKGDLENAFLNLVQCIQN 265 K + GD L+ I N Sbjct: 344 KDDTSGDYRRTLCVLMGEIYN 364 >3BRX-A nrPDB Length = 317 Score = 349 bits (896), Expect = 8e-97, Method: Composition-based stats. Identities = 88/308 (28%), Positives = 144/308 (46%), Gaps = 2/308 (0%) Query: 29 PYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALK 88 P T D + A G +E I++IL +R+ QR I Y ++L AL Sbjct: 8 PTTVPSVSEDCEQLRKAFSGWGTNEGLIIDILGHRNAEQRNLIRKTYAETYGEDLLKALD 67 Query: 89 SALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYK 148 LS E ++L PA+ DA + K + L+EI C+R+ +L + Y Sbjct: 68 KELSNDFERLVLLWALDPAERDALLANEATKRWTSSNQVLMEIACTRSANQLLHARQAYH 127 Query: 149 EMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGT 208 YK LE+D+ T+GDF KL++ L R E G ++ L +A+ L++ + K Sbjct: 128 ARYKKSLEEDVAHHTTGDFHKLLLPLVSSYRYE-GEEVNMTLAKTEAKLLHEK-ISNKAY 185 Query: 209 DVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPL 268 I ++ RS + YK+ D+ + +K + K + + V+C+ Sbjct: 186 SDDDVIRVLATRSKAQINATLNHYKNEYGNDINKDLKADPKDEFLALLRSTVKCLVYPEK 245 Query: 269 YFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQ 328 YF L ++ +GT + L R++ +R+EVD+ I E++R+ L I +DT GDY+ Sbjct: 246 YFEKVLRLAINRRGTDEGALTRVVCTRAEVDLKVIADEYQRRNSVPLTRAIVKDTHGDYE 305 Query: 329 KALLYLCG 336 K LL L G Sbjct: 306 KLLLVLAG 313 Score = 111 bits (278), Expect = 4e-25, Method: Composition-based stats. Identities = 56/250 (22%), Positives = 99/250 (39%), Gaps = 25/250 (10%) Query: 94 HLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKT 153 H T+ + D +L+ + G GT+E +I+I+ R ++ I + Y E Y Sbjct: 1 HHATLTVPTTVPSVSEDCEQLRKAFSGWGTNEGLIIDILGHRNAEQRNLIRKTYAETYGE 60 Query: 154 DLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKW 213 DL K + + S DF +L++ A + ++DA L + KR + Sbjct: 61 DLLKALDKELSNDFERLVLLWA------------LDPAERDA-LLANEATKRWTSSNQVL 107 Query: 214 ISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNK------- 266 + I RS L + Y + + E + GD L LV + + Sbjct: 108 MEIACTRSANQLLHARQAYHARYKKSLEEDVAHHTTGDFHKLLLPLVSSYRYEGEEVNMT 167 Query: 267 -PLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 A L++ + K D +IR++ +RS+ + + +K +YG I +D K Sbjct: 168 LAKTEAKLLHEKISNKAYSDDDVIRVLATRSKAQINATLNHYKNEYG----NDINKDLKA 223 Query: 326 DYQKALLYLC 335 D + L L Sbjct: 224 DPKDEFLALL 233 >1YCN-A nrPDB Length = 317 Score = 344 bits (882), Expect = 4e-95, Method: Composition-based stats. Identities = 101/313 (32%), Positives = 163/313 (52%), Gaps = 9/313 (2%) Query: 31 TNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSA 90 + DA + TA + G +E I++IL +RS QR+ I AY ++L L Sbjct: 9 SVPAPSDDAEQLRTAFEGWGTNEDLIISILAHRSAEQRKVIRQAYHETYGEDLLKTLDKE 68 Query: 91 LSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEM 150 LS E IL P + DA + K + L+E+ C+RT+ +L + Y Sbjct: 69 LSNDFERAILLWTLEPGERDALLANEATKRWTSSNQVLMEVACTRTSTQLLHARQAYHAR 128 Query: 151 YKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDV 210 YK LE+D+ T+GDFRKL+V+L R E G ++ L Q+A+ +++ +K K + Sbjct: 129 YKKSLEEDVAHHTTGDFRKLLVSLVTSYRYE-GDEVNMTLAKQEAKLVHEK-IKDKHYND 186 Query: 211 PKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNL----VQCIQNK 266 I I++ RS + F RY+ ++L+S++ +GD ++ FL L +QC+ Sbjct: 187 EDVIRILSTRSKAQINATFNRYQDDHGEEILKSLE---EGDDDDKFLALLRSTIQCLTRP 243 Query: 267 PLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGD 326 LYF D L ++ GT + L RI+ +R+E+D+ I E++R+ L I +DT+GD Sbjct: 244 ELYFVDVLRSAINKTGTDEGALTRIVTTRAEIDLKVIGEEYQRRNSIPLEKAITKDTRGD 303 Query: 327 YQKALLYLCGGDD 339 Y+K L+ L G DD Sbjct: 304 YEKMLVALLGEDD 316 >1DK5-A nrPDB Length = 322 Score = 336 bits (863), Expect = 5e-93, Method: Composition-based stats. Identities = 89/312 (28%), Positives = 149/312 (47%), Gaps = 6/312 (1%) Query: 29 PYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALK 88 P A D + +A K G +E I++IL +R+ QR+ I Y ++L L Sbjct: 15 PAHVPSAAEDCEQLRSAFKGWGTNEKLIISILAHRTAAQRKLIRQTYAETFGEDLLKELD 74 Query: 89 SALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYK 148 L+ E ++L P++ DA K + K L+E+ C+R+ +EL Y Sbjct: 75 RELTHDFEKLVLVWTLDPSERDAHLAKEATKRWTKSNFVLVELACTRSPKELVLAREAYH 134 Query: 149 EMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGT 208 YK LE+D+ T+GD RKL+V L R G +D L +++ L++ + K Sbjct: 135 ARYKKSLEEDVAYHTTGDHRKLLVPLVSSYRY-GGEEVDLRLAKAESKILHEK-ISDKAY 192 Query: 209 DVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFL-NLVQCIQNKP 267 + I I+ RS L YK D+L+ ++ GD A L ++ + Sbjct: 193 SDDEVIRILATRSKAQLNATLNHYKDEHGEDILKQLED---GDEFVALLRATIKGLVYPE 249 Query: 268 LYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDY 327 YF + L D++ +GT + L R++ +R+EVD+ I E++++ L I +DT+GDY Sbjct: 250 HYFVEVLRDAINRRGTEEDHLTRVIATRAEVDLKIIADEYQKRDSIPLGRAIAKDTRGDY 309 Query: 328 QKALLYLCGGDD 339 + LL L G ++ Sbjct: 310 ESMLLALLGQEE 321 >3CHK-A nrPDB Length = 337 Score = 250 bits (638), Expect = 7e-67, Method: Composition-based stats. Identities = 67/287 (23%), Positives = 127/287 (44%), Gaps = 16/287 (5%) Query: 56 IVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELK 115 ++ I + Q +++ +Q T L + LK LS E+++L L K AQ ++ Sbjct: 32 LIEIARSYPPNQLRNMQRTFQAITGTFLDAFLKKHLSKDFESLVLMLYKPRAQLLCELIR 91 Query: 116 ASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGD---FRKLMV 172 + KG GTDE L++++ + E++EI ++Y ++Y L D++ GD + KL+ Sbjct: 92 GATKGAGTDEKCLVDVLLTIETHEVREIRQLYYQLYNDSL-GDVVRKDCGDKYMWAKLIN 150 Query: 173 ALAKGRR-AEDGSVIDYELIDQDARELYDAGVKRKGT---DVPKWISIMTERSVCHLQKV 228 A+A G R D ++ +L+ L ++ KG +V WI I + +++ Sbjct: 151 AVATGDRIPRDTHELEEDLV------LVRKAIETKGVKKDEVSTWIRIFATYTRADFRQL 204 Query: 229 FERYK-SYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKV 287 + Y Y+ + ++ E +G E AF + + A + + G G+ Sbjct: 205 HKMYSAKYNGDSLRAGVEDEFQGLDEYAFKLAHDFLYDPCCAAAFSMNVAFAGSGSDSNR 264 Query: 288 LIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYL 334 L RI + + +K+ YG++ + KG Y A+ L Sbjct: 265 LNRITAMHFR-ECKGCKYYYKKVYGQAFDERCATELKGVYGDAIKLL 310 Score = 54.6 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 56/129 (43%), Gaps = 5/129 (3%) Query: 212 KWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFA 271 I I L+ + +++ + + +KK + D E+ L L + + Sbjct: 31 DLIEIARSYPPNQLRNMQRTFQAITGTFLDAFLKKHLSKDFESLVLMLYK---PRAQLLC 87 Query: 272 DRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDY--QK 329 + + + KG GT +K L+ ++++ ++ +IR + + Y SL +++D Y K Sbjct: 88 ELIRGATKGAGTDEKCLVDVLLTIETHEVREIRQLYYQLYNDSLGDVVRKDCGDKYMWAK 147 Query: 330 ALLYLCGGD 338 + + GD Sbjct: 148 LINAVATGD 156 Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 43/237 (18%), Positives = 77/237 (32%), Gaps = 29/237 (12%) Query: 39 ALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHL--E 96 I A K G DE +V++L + ++I Y + L ++ Sbjct: 87 CELIRGATKGAGTDEKCLVDVLLTIETHEVREIRQLYYQLYNDSLGDVVRKDCGDKYMWA 146 Query: 97 TVILGLLK-TPAQYDASELKA---------SMKGLGTDE-DSLIEIICSRTNQELQEINR 145 +I + D EL+ KG+ DE + I I + T + +++++ Sbjct: 147 KLINAVATGDRIPRDTHELEEDLVLVRKAIETKGVKKDEVSTWIRIFATYTRADFRQLHK 206 Query: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKR 205 +Y Y D + + D + LA D + + AG Sbjct: 207 MYSAKYNGDSLRAGVEDEFQGLDEYAFKLAHDFLY------DPCCAAAFSMNVAFAGS-- 258 Query: 206 KGTDVPKWISIMTERSVCHLQKVFE---RYKSYSPYDMLESIKKEVKGDLENAFLNL 259 G+D + I + H ++ YK E E+KG +A L Sbjct: 259 -GSDSNRLNRI----TAMHFRECKGCKYYYKKVYGQAFDERCATELKGVYGDAIKLL 310 Score = 42.3 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 61/177 (34%), Gaps = 16/177 (9%) Query: 23 AYGSVKPYTNFDAERDALNIETAVKTKGVDEVTI---VNILTNRSNVQRQDIAFAYQRRT 79 A G P + E D + + A++TKGV + + + I + + + Y + Sbjct: 153 ATGDRIPRDTHELEEDLVLVRKAIETKGVKKDEVSTWIRIFATYTRADFRQLHKMYSAKY 212 Query: 80 -KKELPSALKSALSGHLE---TVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSR 135 L + ++ G E + L P A + + G G+D + L I Sbjct: 213 NGDSLRAGVEDEFQGLDEYAFKLAHDFLYDPCCAAAFSMNVAFAGSGSDSNRLNRITAMH 272 Query: 136 TNQELQEINRVYKEMYKTDLEKDIISDTSG--------DFRKLMVALAKGRRAEDGS 184 +E + YK++Y ++ ++ G + + V L + Sbjct: 273 F-RECKGCKYYYKKVYGQAFDERCATELKGVYGDAIKLLWEPVTVPLLSMDDYQGSE 328 >4EVF-A nrPDB Length = 295 Score = 128 bits (322), Expect = 3e-30, Method: Composition-based stats. Identities = 56/275 (20%), Positives = 103/275 (37%), Gaps = 13/275 (4%) Query: 39 ALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSAL-SGHLET 97 A ++ A+ K DEV I I + S R+ IA AY KELP +K AL G E+ Sbjct: 8 ANELKQAIDAK--DEVQIAFIASEYSAESREKIAKAYVASYGKELPDDIKKALKGGSEES 65 Query: 98 VILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEK 157 +++ L + A ++ ++ G D + + + T ++ E Y M+K L + Sbjct: 66 LLMDLFSDRHEVRAQHIRDALSGR-NDHMAFFDTVILCTPEDWHETVAAYTRMFKKPLVE 124 Query: 158 DIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIM 217 D + D RK L + V + +A+ L A ++ + I Sbjct: 125 DFMKDVG---RKEDWCLLMEKWMAHERVSRPGSPEDEAQRLDQAFDQK---NTAYLIDFF 178 Query: 218 TERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDS 277 + + E +K+ + + ++I F + A + + Sbjct: 179 GTVPSAEYRPIAEAFKAQNGKSIEQAIATIYTKTDYYTFYCAHFALLGMHRLAAYLINCA 238 Query: 278 MKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYG 312 KG +K + RI + L + + + YG Sbjct: 239 CNDKG-DEKRMRRITGMMVD-KCLGAKHAY-KIYG 270 >1BO9-A nrPDB Length = 73 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 37/73 (50%), Positives = 46/73 (63%) Query: 32 NFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSAL 91 F+ D + A+ KGVDE TI++ILT R+N QRQ I AY + T K L LK AL Sbjct: 1 TFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKAL 60 Query: 92 SGHLETVILGLLK 104 +GHLE V+L LLK Sbjct: 61 TGHLEEVVLALLK 73 Score = 48.8 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 35/67 (52%) Query: 110 DASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRK 169 D + L ++ G DE ++I+I+ R N + Q+I Y + L++ + +G + Sbjct: 7 DVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEE 66 Query: 170 LMVALAK 176 +++AL K Sbjct: 67 VVLALLK 73 Score = 48.1 bits (113), Expect = 5e-06, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 193 QDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDL 252 D L+ A + KG D I I+T+R+ Q++ Y + + E++KK + G L Sbjct: 6 SDVAALHKA-IMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHL 64 Query: 253 ENAFLNLVQ 261 E L L++ Sbjct: 65 EEVVLALLK 73 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 32/62 (51%) Query: 274 LYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLY 333 L+ ++ KG + +I I+ R+ +I++ + ++ GK L +++ G ++ +L Sbjct: 11 LHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLA 70 Query: 334 LC 335 L Sbjct: 71 LL 72 >2IIC-A nrPDB Length = 310 Score = 63.5 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 82/207 (39%), Gaps = 11/207 (5%) Query: 52 DEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSAL-SGHLETVILGLLKTPAQYD 110 +E +V + S +R+++ +Q T E + LK + +G E V+ Sbjct: 21 NEEELVTFTSRWSAEERKELRTQFQDTTGLEFIAFLKKCIKNGPYEDVMALGWDCNISAR 80 Query: 111 ASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDT--SGDFR 168 + +K +MK + D ++ +++ T E ++ + YKE DL +D + + Sbjct: 81 VNVIKKAMKNV-NDFRAIHDVVLIATPDERLKLAQAYKEKTGNDLLQDFVDQIPLTSAAS 139 Query: 169 KLMVALAKGRRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKV 228 L + R GS + DA L + D + ++ + +++ Sbjct: 140 YLCHLAIRENRTPRGS------VASDAEVLKHNLIDADEPDHEAVVRLIITSTADEYKEI 193 Query: 229 FERYKSYSPYDMLESIKKEVKGDLENA 255 R++ + + E+I+ D ENA Sbjct: 194 NHRFEVLTGKSVQEAIETRY-ADKENA 219 >1IHU-A nrPDB Length = 589 Score = 34.6 bits (78), Expect = 0.062, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 50/167 (29%), Gaps = 27/167 (16%) Query: 66 VQRQDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDA--SELKASMKGLGT 123 + + KEL A K L L + + A + A ++ + K Sbjct: 389 EETERYRQHVLETKGKELDEAGKRLLEEDLRS---PCTEEIAVFQAFSRVIREAGKR--- 442 Query: 124 DEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRR---- 179 +++ + L + Y + + G F M+ L R Sbjct: 443 --FVVMDTAPTGHTLLLLDATGAYHREIAKKMGEK------GHFTTPMMLLQDPERTKVL 494 Query: 180 ----AEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSV 222 E V++ + D L AG+ G + +SI RS Sbjct: 495 LVTLPETTPVLEAANLQAD---LERAGIHPWGWIINNSLSIADTRSP 538 >5V8F-D nrPDB Length = 529 Score = 31.9 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 54/139 (38%), Gaps = 19/139 (13%) Query: 69 QDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQYDASELKASMK--------- 119 + I F Y + ++E+ +K ++ E+ + L+ Y L + Sbjct: 68 EKIIFTYLQDCQQEIDRIIKQSIIQK-ESHSVILVGPRQSYKTYLLDYELSLLQQSYKEQ 126 Query: 120 -------GLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMV 172 G E + I I ++ Q+LQ+I+ +++ T LE + F K+++ Sbjct: 127 FITIRLNGFIHSEQTAINGIATQLEQQLQKIHGSEEKIDDTSLETISSGSLTEVFEKILL 186 Query: 173 AL--AKGRRAEDGSVIDYE 189 L R ED +D E Sbjct: 187 LLDSTTKTRNEDSGEVDRE 205 >3OCE-A nrPDB Length = 474 Score = 30.7 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 44/111 (39%), Gaps = 9/111 (8%) Query: 184 SVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYD---M 240 +ID L++Q +++ G + ++ R++ HL + Y++ P D M Sbjct: 83 DIIDGLLMEQFVVDVFQGGAGT--SSNMNANEVIANRALEHLGRPRGDYQTIHPNDDVNM 140 Query: 241 LESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRI 291 +S + A L QN+ RL + + KG +I+I Sbjct: 141 SQSTNDVYPTAVRLALLL----SQNQVQTALHRLIAAFEAKGREFATVIKI 187 >3DO5-A nrPDB Length = 327 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 40/110 (36%), Gaps = 7/110 (6%) Query: 42 IETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLETVILG 101 I+ A+ G + +L + R++I A K + KS++SG V Sbjct: 3 IKIAIVGFGTVGQGVAELLIRK----REEIEKA-IGEFKVTAVADSKSSISGDFSLVEAL 57 Query: 102 LLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTN--QELQEINRVYKE 149 +K + KA D D LIE +R + + + I K Sbjct: 58 RMKRETGMLRDDAKAIEVVRSADYDVLIEASVTRVDGGEGVNYIREALKR 107 >2ZQJ-A nrPDB Length = 417 Score = 29.6 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 53/153 (34%), Gaps = 10/153 (6%) Query: 53 EVTIVNILTNRSNVQRQDIAFAYQRRTKKELPSALKSALSGHLETVILGLLKTPAQ-YDA 111 E V T+R Q + + + H + + L L+ P Q A Sbjct: 53 EAAKVFYDTDRFQRQNALPKRVQKSLFGVNAIQGMDGSAHIHRKMLFLSLMTPPHQKRLA 112 Query: 112 SELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLM 171 + K T + E++ +E+ Y L++ + + + DF ++ Sbjct: 113 ELMTEEWKAAVTRWEKADEVVLFEEAKEILCRVACYWA--GVPLKETEVKERADDFIDMV 170 Query: 172 VALA-------KGRRAEDGSVIDYELIDQDARE 197 A KGRRA + E++ +DAR Sbjct: 171 DAFGAVGPRHWKGRRARPRAEEWIEVMIEDARA 203 >3IYJ-F nrPDB Length = 495 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 25 GSVKPYTNFDAERDALNIETAVKTKGVDE 53 G+V + F+A DA N+ V T+ D+ Sbjct: 111 GTVTGHPTFNALLDAENVNRKVTTQTTDD 139 >3AMU-A nrPDB Length = 440 Score = 28.4 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 35/108 (32%), Gaps = 9/108 (8%) Query: 207 GTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNK 266 G ++ + + Y S +DM + + +++ +V CI N Sbjct: 170 GAELEDFTLELIAYRYPERFGTEREYDEESFFDMDYELYPQTFDNVDWCNDVVV-CIPNT 228 Query: 267 PLYF--------ADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSE 306 P + LY +M+ T I V+ DM I E Sbjct: 229 PCPVLYGIRGESVEALYKAMESVKTEPVDRRMIFVTNHATDMHLIGEE 276 >3AU7-A nrPDB Length = 402 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 35/108 (32%), Gaps = 9/108 (8%) Query: 207 GTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNK 266 G ++ + + Y S +DM + + +++ +V CI N Sbjct: 170 GAELEDFTLELIAYRYPERFGTEREYDEESFFDMDYELYPQTFDNVDWCNDVVV-CIPNT 228 Query: 267 PLYF--------ADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSE 306 P + LY +M+ T I V+ DM I E Sbjct: 229 PCPVLYGIRGESVEALYKAMESVKTEPVDRRMIFVTNHATDMHLIGEE 276 >4WXH-A nrPDB Length = 367 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 24/76 (31%), Gaps = 10/76 (13%) Query: 105 TPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTS 164 AQ +L ++ +I +R ++ Y+ +Y +D+ Sbjct: 110 PAAQRAWHDLTQAVARA--------DISFTRLPDAIRTGRPTYESIYGKPFYEDLAGRP- 160 Query: 165 GDFRKLMVALAKGRRA 180 D R +L + Sbjct: 161 -DLRASFDSLLACDQD 175 >6CNF-S nrPDB Length = 594 Score = 27.7 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 6/72 (8%) Query: 29 PYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKE---LPS 85 YT+ + + A+ G D I + RS R+ + + KK + Sbjct: 415 SYTDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRS---RKQVKAKFVNEEKKRPILIEL 471 Query: 86 ALKSALSGHLET 97 AL+S L + + Sbjct: 472 ALRSKLPPNFDE 483 >6F41-W nrPDB Length = 594 Score = 27.7 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 6/72 (8%) Query: 29 PYTNFDAERDALNIETAVKTKGVDEVTIVNILTNRSNVQRQDIAFAYQRRTKKE---LPS 85 YT+ + + A+ G D I + RS R+ + + KK + Sbjct: 415 SYTDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRS---RKQVKAKFVNEEKKRPILIEL 471 Query: 86 ALKSALSGHLET 97 AL+S L + + Sbjct: 472 ALRSKLPPNFDE 483 >2J41-A nrPDB Length = 207 Score = 27.7 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 4/72 (5%) Query: 237 PYDMLESIKKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGT--RDKVLIRIMVS 294 +D+ I+ E + F + + P + L + + G+GT +K+ RI + Sbjct: 97 GHDVFLEIEVEGAKQVRKKFPDALFIFLAPPSL--EHLRERLVGRGTESDEKIQSRINEA 154 Query: 295 RSEVDMLKIRSE 306 R EV+M+ + Sbjct: 155 RKEVEMMNLYDY 166 >2EJ9-A nrPDB Length = 237 Score = 27.7 bits (60), Expect = 8.6, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 51 VDEVTIVNILTNRSNVQRQDIAF---AYQRRTKKELPS-ALKSALSGHLETVI 99 D+ I+ I N +N R +I + + T KEL + S E+ + Sbjct: 115 TDDYMIIGIGINVNNQIRNEIREIAISLKEITGKELDKVEILSNFLKTFESYL 167 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.141 0.365 Lambda K H 0.267 0.0430 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,630,628 Number of Sequences: 36641 Number of extensions: 498286 Number of successful extensions: 2129 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 52 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 1557 Number of HSP's gapped (non-prelim): 130 length of query: 339 length of database: 10,336,785 effective HSP length: 98 effective length of query: 241 effective length of database: 6,745,967 effective search space: 1625778047 effective search space used: 1625778047 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.7 bits)