BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07342 (687 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1T9B-A nrPDB 1301 0.0 6DEO-A nrPDB 963 0.0 5WJ1-A nrPDB 455 e-128 2PAN-A nrPDB 266 2e-71 5AHK-A nrPDB 243 2e-64 4RJK-A nrPDB 214 9e-56 5D6R-B nrPDB 187 1e-47 3EYA-A nrPDB 174 1e-43 1V5E-A nrPDB 169 4e-42 2EZ4-A nrPDB 164 1e-40 6A50-A nrPDB 156 3e-38 2PGN-A nrPDB 139 4e-33 4QQ8-A nrPDB 137 2e-32 1UPC-A nrPDB 132 4e-31 2Q28-A nrPDB 125 8e-29 2JI6-A nrPDB 118 7e-27 4Q9D-A nrPDB 105 6e-23 2VBF-A nrPDB 99 6e-21 1OVM-A nrPDB 91 1e-18 2Q5O-A nrPDB 90 4e-18 4K9Q-A nrPDB 89 5e-18 1QPB-A nrPDB 86 5e-17 6EFG-A nrPDB 83 5e-16 5NPU-A nrPDB 77 2e-14 4ZP1-A nrPDB 57 3e-08 4COK-A nrPDB 55 1e-07 5EUJ-A nrPDB 52 9e-07 2VBI-A nrPDB 50 2e-06 3LQ1-A nrPDB 47 2e-05 2JLA-A nrPDB 47 3e-05 5ESS-A nrPDB 46 5e-05 2X7J-A nrPDB 38 0.013 1MJG-A nrPDB 31 1.4 4ZEN-A nrPDB 30 2.4 1CJS-A nrPDB 30 4.0 3DC2-A nrPDB 29 5.8 2O6L-A nrPDB 29 6.8 2I2W-A nrPDB 29 8.3 >1T9B-A nrPDB Length = 677 Score = 1301 bits (3368), Expect = 0.0, Method: Compositional matrix adjust. Identities = 630/630 (100%), Positives = 630/630 (100%) Query: 58 APSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGA 117 APSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGA Sbjct: 48 APSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGA 107 Query: 118 ILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADA 177 ILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADA Sbjct: 108 ILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADA 167 Query: 178 FADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIA 237 FADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIA Sbjct: 168 FADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIA 227 Query: 238 TSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLIN 297 TSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLIN Sbjct: 228 TSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLIN 287 Query: 298 LAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGC 357 LAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGC Sbjct: 288 LAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGC 347 Query: 358 ATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVV 417 ATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVV Sbjct: 348 ATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVV 407 Query: 418 QTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVI 477 QTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVI Sbjct: 408 QTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVI 467 Query: 478 KKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQV 537 KKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQV Sbjct: 468 KKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQV 527 Query: 538 AKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSH 597 AKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSH Sbjct: 528 AKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSH 587 Query: 598 THQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAG 657 THQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAG Sbjct: 588 THQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAG 647 Query: 658 GSGLDEFINFDPEVERQQTELRHKRTGGKH 687 GSGLDEFINFDPEVERQQTELRHKRTGGKH Sbjct: 648 GSGLDEFINFDPEVERQQTELRHKRTGGKH 677 >6DEO-A nrPDB Length = 682 Score = 963 bits (2490), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/656 (69%), Positives = 542/656 (82%), Gaps = 11/656 (1%) Query: 42 RYYSASPLPASKRPEPAPSFNV----------DPLEQPAEPSKLAKKLRAEPDMDTSFVG 91 R + SP + + A +FN DP + S +++K + E MD SF+G Sbjct: 28 RQHMDSPDLGTDDDDKAMAFNTADTSTQPIINDPTLNKHQSSAISRK-KKEQLMDDSFIG 86 Query: 92 LTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYAR 151 LTGG+IF+EMM R VDTVFGY GGAILPV+DAI+NSDKF FVLP+HEQGAGHMAEGYAR Sbjct: 87 LTGGEIFHEMMLRHKVDTVFGYAGGAILPVFDAIYNSDKFKFVLPRHEQGAGHMAEGYAR 146 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISR 211 ASGKPGVVLVTSGPGATNV+TPMADA DG+P+VVF+GQVPT+AIGTDAFQEAD+VGISR Sbjct: 147 ASGKPGVVLVTSGPGATNVITPMADALMDGVPLVVFSGQVPTTAIGTDAFQEADIVGISR 206 Query: 212 SCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSN 271 SCTKWNVMVK+V ELP RINEAFEIAT+GRPGPVLVDLPKDVTA+ILR IP TTLPSN Sbjct: 207 SCTKWNVMVKNVAELPRRINEAFEIATTGRPGPVLVDLPKDVTASILRESIPINTTLPSN 266 Query: 272 ALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPV 331 AL+Q+T +A EF ++I +AA+++N AKKP++Y GAGILN+ GP+LLKEL+D+A IPV Sbjct: 267 ALSQITKKAVSEFTSEAIKRAANILNKAKKPIIYAGAGILNNEQGPKLLKELADKANIPV 326 Query: 332 TTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPE 391 TTTLQGLG+FDQ DPKSLDMLGMHG A AN A+QNAD IIA+GARFDDRVTGNISKFAPE Sbjct: 327 TTTLQGLGAFDQRDPKSLDMLGMHGSAAANTAIQNADCIIALGARFDDRVTGNISKFAPE 386 Query: 392 ARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQI 451 A+ AA+EGRGGI+HFE+SPKNINKVV+ A+EGD T NL + + ++ R EWF +I Sbjct: 387 AKLAASEGRGGILHFEISPKNINKVVEATEAIEGDVTANLQSFIPLVDSIENRPEWFNKI 446 Query: 452 NKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWR 511 N+WKK+YPY+Y ETPGS IKPQT+IK++S A + VIVTTGVGQHQMWAAQH+TW Sbjct: 447 NEWKKKYPYSYQLETPGSLIKPQTLIKEISDQAQTYNKEVIVTTGVGQHQMWAAQHFTWT 506 Query: 512 NPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVK 571 P T ITSGGLGTMGYGLPAAIGAQVAKP+++VIDIDGDASFNMTLTELSSAVQAG P+K Sbjct: 507 QPRTMITSGGLGTMGYGLPAAIGAQVAKPDAIVIDIDGDASFNMTLTELSSAVQAGAPIK 566 Query: 572 ILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKE 631 + +LNNEEQGMVTQWQSLFYEHRYSHTHQ NPDF+KLAE+M +KG+R+ Q+EL + +KE Sbjct: 567 VCVLNNEEQGMVTQWQSLFYEHRYSHTHQSNPDFMKLAESMNVKGIRITNQQELKSGVKE 626 Query: 632 FVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRTGGKH 687 F+ PVLLEV V+KKVPVLPMV G LD+FI +D EVE+QQ +LR +RTGGK+ Sbjct: 627 FLDATEPVLLEVIVEKKVPVLPMVPAGKALDDFILWDAEVEKQQNDLRKERTGGKY 682 >5WJ1-A nrPDB Length = 590 Score = 455 bits (1171), Expect = e-128, Method: Compositional matrix adjust. Identities = 252/588 (42%), Positives = 356/588 (60%), Gaps = 41/588 (6%) Query: 94 GGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARAS 153 G I E + RQ V+TVF YPGGA + ++ A+ S VLP+HEQG AEGYAR+S Sbjct: 14 GADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSS 73 Query: 154 GKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSC 213 GKPG+ + TSGPGATN+V+ +ADA D +P+V TGQVP IGTDAFQE +V ++RS Sbjct: 74 GKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSI 133 Query: 214 TKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNAL 273 TK N +V VE++P I EAF +ATSGRPGPVLVD+PKD+ + LP + Sbjct: 134 TKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLP-GYM 192 Query: 274 NQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTT 333 +++ +D + Q + LI+ +KKPVLYVG G LN +D EL+ IPV + Sbjct: 193 SRMPKPPEDSHLEQIVR----LISESKKPVLYVGGGCLNSSDELGRFVELTG---IPVAS 245 Query: 334 TLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEAR 393 TL GLGS+ +D SL MLGMHG AN AV+++DL++A G RFDDRVTG + FA A+ Sbjct: 246 TLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFASRAK 305 Query: 394 RAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSE------- 446 I+H ++ I K ++V GD L + M+K+ ++ R+E Sbjct: 306 ---------IVHIDIDSAEIGKNKTPHVSVCGDVKLAL-QGMNKV--LENRAEELKLDFG 353 Query: 447 -WFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAA 505 W ++N K+++P ++ +T G I PQ IK L ++ T I++TGVGQHQMWAA Sbjct: 354 VWRNELNVQKQKFPLSF--KTFGEAIPPQYAIKVLDEL---TDGKAIISTGVGQHQMWAA 408 Query: 506 QHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQ 565 Q + ++ P +++SGGLG MG+GLPAAIGA VA P+++V+DIDGD SF M + EL++ Sbjct: 409 QFYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRV 468 Query: 566 AGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTH--------QLNPDFIKLAEAMGLKGL 617 PVK+L+LNN+ GMV QW+ FY+ +HT ++ P+ + A A G+ Sbjct: 469 ENLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAA 528 Query: 618 RVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFI 665 RV K+ +L ++ + T GP LL+V + VLPM+ G ++ I Sbjct: 529 RVTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVI 576 >2PAN-A nrPDB Length = 616 Score = 266 bits (681), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 186/594 (31%), Positives = 293/594 (49%), Gaps = 58/594 (9%) Query: 101 MMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARAS-GKPGVV 159 ++ ++ + T FG PG AI P Y A+ +L +H +GA HMAEGY RA+ G GV Sbjct: 36 VLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVC 95 Query: 160 LVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVM 219 L TSGP T+++T + A AD IP++ TGQ P + + + FQ D+ I++ +K V Sbjct: 96 LGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVT 155 Query: 220 VKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSR 279 V+ +P + +AF + SGRPGPVLVDLP DV A + LP SR Sbjct: 156 VREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEPLP--VYKPAASR 213 Query: 280 AQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLG 339 Q I KA +++ A++PV+ G G++N AD LL++ ++ +PV TL G G Sbjct: 214 MQ-------IEKAVEMLIQAERPVIVAGGGVIN-ADAAALLQQFAELTSVPVIPTLMGWG 265 Query: 340 SFDQEDPKSLDMLGMHGCATA----NLAVQNADLIIAVGARFDDRVTGNISKFAPEARRA 395 D L M GM G TA N + +D++ +G RF +R TG++ K+ Sbjct: 266 CI--PDDHEL-MAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKY------- 315 Query: 396 AAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNL------GKMMSKIFPVKERSEWFA 449 EGR I+H ++ P I +V+ + + DA L + M K + R EW A Sbjct: 316 -TEGR-KIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVA 373 Query: 450 QINKWKKE-YPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHW 508 + K+ + + P +KPQ V ++++K GR V T +G Q+ AAQ Sbjct: 374 DCQQRKRTLLRKTHFDNVP---VKPQRVYEEMNKA---FGRDVCYVTTIGLSQIAAAQML 427 Query: 509 TWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGT 568 +I G G +G+ +PAA+G A P+ V+ I GD F + EL+ Q Sbjct: 428 HVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNI 487 Query: 569 PVKILILNNEEQGMVTQWQSLF---------YEH-RYSHTHQLNPDFIKLAEAMGLKGLR 618 P +++NN G++ Q Q F +E+ S + D +K+AE +G K +R Sbjct: 488 PYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIR 547 Query: 619 VKKQEELDAKLKE----FVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFD 668 V K E++ ++ + PV++EV +++ + ++ GS LD + F+ Sbjct: 548 VFKPEDIAPAFEQAKALMAQYRVPVVVEVILER----VTNISMGSELDNVMEFE 597 >5AHK-A nrPDB Length = 588 Score = 243 bits (619), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 178/581 (30%), Positives = 281/581 (48%), Gaps = 45/581 (7%) Query: 100 EMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKP--G 157 ++++ NV F GG I + D+I+ K V HEQGA A +R + G Sbjct: 29 KILADNNVLYGFELIGGMITHLVDSINLLGKTKLVSMHHEQGAAFAASAVSRVTHHKTLG 88 Query: 158 VVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSA------IGTDAFQEADVVGISR 211 + L TSGPGATN++T +AD + D P + TGQV T I FQE D V + Sbjct: 89 LALATSGPGATNLITGIADCWLDSHPCIFLTGQVNTHELKGKRDIRQQGFQELDSVALVT 148 Query: 212 SCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLP-----KDVTAAILRNPI--PT 264 S TK+ +KS +EL + +A +IA GRPGPVL+D+P D+ A+L NP+ Sbjct: 149 SITKYAYQIKSADELVPCLRKAIQIAKEGRPGPVLLDIPMDIQRADIDEALLNNPMTPEP 208 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 K PS A++ L +F+ INK + AKKP+L +G G +N + + L+++ Sbjct: 209 KVQRPSIAMSDL------DFI---INKLQN----AKKPLLLIGGGAVNSSGFQKWLEQIE 255 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGN 384 R IP +L+G D L MLG +G AN AVQN DL++ +G+R D R TG Sbjct: 256 LRG-IPYVASLKGAEKIKASD-LYLGMLGAYGTRAANHAVQNCDLLLVLGSRMDVRQTGA 313 Query: 385 ISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKER 444 PE AE II ++ +N V + + + + + PV Sbjct: 314 ----QPEDFARNAE----IIQIDLQEGQLNNRVIADFSYQIELSEYFSRFSPLQIPVN-- 363 Query: 445 SEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWA 504 ++W K+++ +++E + P + +L+K+ I+ VG +QMWA Sbjct: 364 NDWSVWTALLKEKFRVTFIDEYTTWNLSPFGLFTQLNKLTERVALDYILD--VGNNQMWA 421 Query: 505 AQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAV 564 A SGGLG+MG+ +PAAIGA A + +++ I GD + + EL Sbjct: 422 AHTLRLNAQQAMHHSGGLGSMGFAIPAAIGACYAGKKPIIV-ITGDGGAQLNIQELDIIA 480 Query: 565 QAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQ--LNPDFIKLAEAMGLKGLRVKKQ 622 + P+ +++NN GMV +Q +++E R S T+ F K+ EA ++ + Sbjct: 481 RDKLPILTIVMNNHSLGMVRGFQEMYFEGRNSSTYWNGYTSQFKKIGEAYRVESKTIISM 540 Query: 623 EELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDE 663 + + L+ F+ + P+LLEV + P + G +D+ Sbjct: 541 QAFSSALESFLESPRPLLLEVSMSDARECRPRLEYGRAIDQ 581 >4RJK-A nrPDB Length = 571 Score = 214 bits (545), Expect = 9e-56, Method: Compositional matrix adjust. Identities = 165/568 (29%), Positives = 273/568 (48%), Gaps = 41/568 (7%) Query: 88 SFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAE 147 S V G ++ + + Q V VFG PG I V+DA+ + ++ +HEQ A MA+ Sbjct: 11 SLVKNRGAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKGP-EIIVARHEQNAAFMAQ 69 Query: 148 GYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVV 207 R +GKPGVVLVTSGPGA+N+ T + A +G P+V G V + Q D Sbjct: 70 AVGRLTGKPGVVLVTSGPGASNLATGLLTANTEGDPVVALAGNVIRADRLKRTHQSLDNA 129 Query: 208 GISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTT 267 + + TK++V V+ V+ +P + AF IA++G+ G V P+DV N + Sbjct: 130 ALFQPITKYSVEVQDVKNIPEAVTNAFRIASAGQAGAAFVSFPQDVV-----NEVTNTKN 184 Query: 268 LPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRA 327 + + A +L A D I AK PV+ VG + + +++L + Sbjct: 185 VRAVAAPKLGPAADDAISAAIAK-----IQTAKLPVVLVGMK-GGRPEAIKAVRKLLKKV 238 Query: 328 QIPVTTTLQGLGSF--DQEDPKSLDMLGMHGCATANLAVQNADLIIAVG---ARFDDRVT 382 Q+P T Q G+ D ED + +G+ +L ++ AD+++ +G +D + Sbjct: 239 QLPFVETYQAAGTLSRDLED-QYFGRIGLFRNQPGDLLLEQADVVLTIGYDPIEYDPKFW 297 Query: 383 GNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVK 442 NI+ G IIH + +I+ Q + + GD + + + V Sbjct: 298 -NIN------------GDRTIIHLDEIIADIDHAYQPDLELIGDIPSTINHIEHDAVKV- 343 Query: 443 ERSEWFAQINKWKKEYPYAYMEETPGS----KIKPQTVIKKLSKVANDTGRHVIVTTGVG 498 E +E +I K+Y + E+ P + P ++K+L +D HV VT +G Sbjct: 344 EFAEREQKILSDLKQYMHE-GEQVPADWKSDRAHPLEIVKELRNAVDD---HVTVTCDIG 399 Query: 499 QHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLT 558 H +W ++++ P T + S G+ T+G LP AIGA + KP V+ + GD F + Sbjct: 400 SHAIWMSRYFRSYEPLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDGGFLFSAM 459 Query: 559 ELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLR 618 EL +AV+ P+ ++ N+ MV +Q L +R S N D +K AE+ G GLR Sbjct: 460 ELETAVRLKAPIVHIVWNDSTYDMVA-FQQLKKYNRTSAVDFGNIDIVKYAESFGATGLR 518 Query: 619 VKKQEELDAKLKEFVSTKGPVLLEVEVD 646 V+ ++L L++ ++ +GPV+++V VD Sbjct: 519 VESPDQLADVLRQGMNAEGPVIIDVPVD 546 >5D6R-B nrPDB Length = 579 Score = 187 bits (476), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 155/561 (27%), Positives = 253/561 (45%), Gaps = 35/561 (6%) Query: 94 GGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARAS 153 G + + Q V VFG PG I V+D++ +S + +HE A MA R + Sbjct: 33 GADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDS-SIRIIPVRHEANAAFMAAAVGRIT 91 Query: 154 GKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSC 213 GK GV LVTSGPG +N++T MA A ++G P+V G V + Q D V + Sbjct: 92 GKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPV 151 Query: 214 TKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNAL 273 TK+ + V + + L ++ AF A GRPG V LP+DV + P+ K LP++ Sbjct: 152 TKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDV----VDGPVSGK-VLPASGA 206 Query: 274 NQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTT 333 Q+ + D +I++ A LI AK P+ +G + + + + L+ L + + IPVT+ Sbjct: 207 PQMGAAPDD-----AIDQVAKLIAQAKNPIFLLGL-MASQPENSKALRRLLETSHIPVTS 260 Query: 334 TLQGLGSFDQED-PKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEA 392 T Q G+ +Q++ + +G+ + +Q ADL+I +G ++P Sbjct: 261 TYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIG-------------YSPVE 307 Query: 393 RRAAA--EGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQ 450 A G ++H +V P + + + GD L K+ I S A+ Sbjct: 308 YEPAMWNSGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAE 367 Query: 451 I---NKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQH 507 I + ++E + + P +++ + + N V +T +G +W A++ Sbjct: 368 ILRDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSD---VTLTVDMGSFHIWIARY 424 Query: 508 WTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAG 567 + S G TMG LP AIGA + PE V+ + GD F + EL +AV+ Sbjct: 425 LYSFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLK 484 Query: 568 TPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDA 627 V LI + MV + Y+ R S DF AE+ G KG V+ E L+ Sbjct: 485 ANVLHLIWVDNGYNMVAIQEEKKYQ-RLSGVEFGPMDFKAYAESFGAKGFAVESAEALEP 543 Query: 628 KLKEFVSTKGPVLLEVEVDKK 648 L+ + GP ++ + VD + Sbjct: 544 TLRAAMDVDGPAVVAIPVDYR 564 >3EYA-A nrPDB Length = 549 Score = 174 bits (441), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 144/558 (25%), Positives = 255/558 (45%), Gaps = 41/558 (7%) Query: 102 MSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLV 161 + V ++G G ++ + D+++ ++ +HE+ A A A+ SG+ V Sbjct: 13 LESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELAVCAG 72 Query: 162 TSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVK 221 + GPG +++ + D + +P++ +P+S IG+ FQE + R C+ + +V Sbjct: 73 SCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVS 132 Query: 222 SVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQ 281 S E++P + A A R G +V LP DV P P T+ Q + Sbjct: 133 SPEQIPQVLAIAMRKAVLNR-GVSVVVLPGDVAL----KPAPEGATMHWYHAPQPVVTPE 187 Query: 282 DEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSF 341 +E + K A L+ + L G+G A + L E + + + P+ L+G Sbjct: 188 EE----ELRKLAQLLRYSSNIALMCGSGC---AGAHKELVEFAGKIKAPIVHALRGKEHV 240 Query: 342 DQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRG 401 + ++P + M G+ G ++ + NAD ++ +G +F R F P + Sbjct: 241 EYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRA------FYPTDAK------- 287 Query: 402 GIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYA 461 II +++P +I + +A+ GD + L + P+ E ++K ++Y A Sbjct: 288 -IIQIDINPASIGAHSKVDMALVGDIKSTL----RALLPLVEEKADRKFLDKALEDYRDA 342 Query: 462 Y-----MEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTF 516 + + I PQ + +++S A D I T VG +WAA++ Sbjct: 343 RKGLDDLAKPSEKAIHPQYLAQQISHFAADDA---IFTCDVGTPTVWAARYLKMNGKRRL 399 Query: 517 ITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILN 576 + S G+M +P A+GAQ +PE V+ + GD F+M + + S VQ PVKI++ N Sbjct: 400 LGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMKLPVKIVVFN 459 Query: 577 NEEQGMVT-QWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVST 635 N G V + ++ Y + H N F ++AEA G+ G+RV+K E+D L+ S Sbjct: 460 NSVLGFVAMEMKAGGYLTDGTELHDTN--FARIAEACGITGIRVEKASEVDEALQRAFSI 517 Query: 636 KGPVLLEVEVDKKVPVLP 653 GPVL++V V K+ +P Sbjct: 518 DGPVLVDVVVAKEELAIP 535 >1V5E-A nrPDB Length = 590 Score = 169 bits (428), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 142/569 (24%), Positives = 259/569 (45%), Gaps = 52/569 (9%) Query: 100 EMMSRQNVDTVFGYPGGAILPVYDAI-HNSDKFNFVLPKHEQGAGHMAEGYARASGKPGV 158 +++ DT++G P G + + DA+ + F+ KHE+ A ++ G GV Sbjct: 12 KILESWGADTIYGIPSGTLSSLMDAMGEEENNVKFLQVKHEEVGAMAAVMQSKFGGNLGV 71 Query: 159 VLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNV 218 + + GPGA++++ + DA D IP+V G P + DAFQE + + +N Sbjct: 72 TVGSGGPGASHLINGLYDAAMDNIPVVAILGSRPQRELNMDAFQELNQNPMYDHIAVYNR 131 Query: 219 MVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTS 278 V E+LP ++EA +A + R G ++++P D + N + +N+L + Sbjct: 132 RVAYAEQLPKLVDEAARMAIAKR-GVAVLEVPGDFAKVEIDN---DQWYSSANSLRKYAP 187 Query: 279 RAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGL 338 A Q I+ A +L+N +K+PV+Y G G + H GP ++EL+ + + PV TT + Sbjct: 188 IAP---AAQDIDAAVELLNNSKRPVIYAGIGTMGH--GPA-VQELARKIKAPVITTGKNF 241 Query: 339 GSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFD-DRVTG---NISKFAPEARR 394 +F+ + G AN + AD ++ G+ F V G N+ F Sbjct: 242 ETFEWDFEALTGSTYRVGWKPANETILEADTVLFAGSNFPFSEVEGTFRNVDNF------ 295 Query: 395 AAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKW 454 I ++ P + K +A+ GDA + ++++K+ V+E + W A + Sbjct: 296 ---------IQIDIDPAMLGKRHHADVAILGDAALAIDEILNKVDAVEESAWWTANLKNI 346 Query: 455 KKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPH 514 Y M ET + + + + N I + VG + +H + Sbjct: 347 ANWREYINMLET--KEEGDLQFYQVYNAINNHADEDAIYSIDVGNSTQTSIRHLHMTPKN 404 Query: 515 TFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILI 574 + TS TMG +P +GA+ P+ V +I GD +F+MT ++ + V+ PV ++ Sbjct: 405 MWRTSPLFATMGIAIPGGLGAKNTYPDRQVWNIIGDGAFSMTYPDVVTNVRYNMPVINVV 464 Query: 575 LNNEEQGMVTQWQSLFYEHRYSHTHQ-------LNPDFIKLAEAMGLKGLRVKKQEELDA 627 +N E F +++Y T++ + D+ K+AEA G KG V + E++D Sbjct: 465 FSNTEYA--------FIKNKYEDTNKNLFGVDFTDVDYAKIAEAQGAKGFTVSRIEDMDR 516 Query: 628 KLKEFVSTKGP---VLLEVEV--DKKVPV 651 + E V+ V+++ ++ D+ +PV Sbjct: 517 VMAEAVAANKAGHTVVIDCKITQDRPIPV 545 >2EZ4-A nrPDB Length = 603 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 143/573 (24%), Positives = 264/573 (46%), Gaps = 36/573 (6%) Query: 87 TSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIH-NSDKFNFVLPKHEQGAGHM 145 T + G +++ VD ++G PGG+I + DA+ D+ +++ +HE+ Sbjct: 6 TKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALSAERDRIHYIQVRHEEVGAMA 65 Query: 146 AEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEAD 205 A A+ +GK GV ++GPG T+++ + DA D +P++ GQ T+ + D FQE + Sbjct: 66 AAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPVLALIGQFGTTGMNMDTFQEMN 125 Query: 206 VVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTK 265 I +NV + LP I+EA A + + G +V +P D+ IP + Sbjct: 126 ENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQ-GVAVVQIPVDLP----WQQIPAE 180 Query: 266 TTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSD 325 S N + E +Q++ + + A++P++Y G G + L++LS Sbjct: 181 DWYAS--ANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIGARKAG---KELEQLSK 235 Query: 326 RAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNI 385 +IP+ +T G P L AN A+ AD+++ VG + Sbjct: 236 TLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVLFVGNNY-------- 287 Query: 386 SKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERS 445 FA E +A R + ++ P + K +T IAV DA L +++++ +E + Sbjct: 288 -PFA-EVSKAFKNTR-YFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSE-REST 343 Query: 446 EWF----AQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQ 501 W+ A + W+ A +E+ ++ V++ ++K+A I + VG Sbjct: 344 PWWQANLANVKNWRAY--LASLEDKQEGPLQAYQVLRAVNKIAEPDA---IYSIDVGDIN 398 Query: 502 MWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELS 561 + A +H + ITS TMG G+P AI A++ PE V ++ GD +MT+ +L+ Sbjct: 399 LNANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA 458 Query: 562 SAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKK 621 + VQ PV ++ N + G + Q ++ + + DF K+A+ + ++ RV K Sbjct: 459 TQVQYHLPVINVVFTNCQYGWIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVNK 518 Query: 622 QEELDAKLKE--FVSTKGPVLLEVEV--DKKVP 650 E+L ++ ++ PVL++ + D+ +P Sbjct: 519 IEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLP 551 >6A50-A nrPDB Length = 549 Score = 156 bits (395), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 147/553 (26%), Positives = 244/553 (44%), Gaps = 50/553 (9%) Query: 100 EMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVV 159 E++ RQ +DTVFG PG LP + F ++L E +A+GYA+AS KP + Sbjct: 31 ELLRRQGIDTVFGNPGSNELPFLKDF--PEDFRYILALQEACVVGIADGYAQASRKPAFI 88 Query: 160 LVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQ-EADVVGISRSCTKWNV 218 + S G N + +++A P++V GQ + IG +A + D + R KW+ Sbjct: 89 NLHSAAGTGNAMGALSNARTSHSPLIVTAGQQTRAMIGVEAGETNVDAANLPRPLVKWSY 148 Query: 219 MVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTS 278 S E+P ++ A +A+ GPV + +P D ++ P L ++ + Sbjct: 149 EPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWD---KDADPQSHHLFDRHVSS-SV 204 Query: 279 RAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQG- 337 R D Q ++ +N A P + +G + + A+ L++R + PV Sbjct: 205 RLND----QDLDILVKALNSASNPAIVLGPDV-DAANANADCVMLAERLKAPVWVAPSAP 259 Query: 338 LGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAA 397 F P L G A + ++ D+++ +GA V + ++ R Sbjct: 260 RCPFPTRHP-CFRGLMPAGIAAISQLLEGHDVVLVIGAPVFRYVFYDPGQYLKPGTR--- 315 Query: 398 EGRGGIIHFEVSPKNINKVVQTQIAVEGDA-TTNLGKMMSKIFPVKERSEWFAQINKWKK 456 +I P ++ A GDA ++G M S + + E S + Sbjct: 316 -----LISVTCDP------LEAARAPMGDAIVADIGAMASALANLVEES---------SR 355 Query: 457 EYPYAYME----ETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRN 512 + P A E + ++ P+TV L+ +A + ++ +T QMW Q RN Sbjct: 356 QLPTAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTST-TAQMW--QRLNMRN 412 Query: 513 P--HTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPV 570 P + F +GGLG + LPAAIG Q+A+PE VI + GD S N +++ L +A Q P Sbjct: 413 PGSYYFCAAGGLG---FALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPT 469 Query: 571 KILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLK 630 +I+NN GM+ + + DF LA+ G++ L+ E+L L+ Sbjct: 470 IFVIMNNGTYGMLRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQ 529 Query: 631 EFVSTKGPVLLEV 643 E +S KGPVL+EV Sbjct: 530 EALSAKGPVLIEV 542 >2PGN-A nrPDB Length = 589 Score = 139 bits (350), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 145/594 (24%), Positives = 247/594 (41%), Gaps = 66/594 (11%) Query: 94 GGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVL-PKHEQGAGHMAEGYARA 152 G + E + + V G+ G V DA S V+ P E G M GY Sbjct: 6 GADLIVEALEEYGTEQVVGFIGHTSHFVADAFSKSHLGKRVINPATELGGAWMVNGYNYV 65 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRS 212 + V G + M +A TG++P IG ++ + + G S + Sbjct: 66 KDRSAAVGAWHCVGNLLLHAAMQEAR---------TGRIPAVHIGLNS--DGRLAGRSEA 114 Query: 213 CTK--WNVM---------VKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNP 261 + W V+ ++++ I+EAF +A GP VD+P D+TA + Sbjct: 115 AQQVPWQSFTPIARSTQRVERLDKVGEAIHEAFRVAEGHPAGPAYVDIPFDLTA----DQ 170 Query: 262 IPTKTTLPSNALNQLTSRAQDEFVM--QSINKAADLINLAKKPVLYVGAGILNHADGPRL 319 I K +P A +RA+ + + +AA + AK PV+ G G+ L Sbjct: 171 IDDKALVPRGA-----TRAKSVLHAPNEDVREAAAQLVAAKNPVILAGGGVARSGGSEAL 225 Query: 320 LKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDD 379 LK L++ +PV TT G G F + ++ G G +AN + AD ++ +G+R D Sbjct: 226 LK-LAEMVGVPVVTTSTGAGVFPETHALAMGSAGFCGWKSANDMMAAADFVLVLGSRLSD 284 Query: 380 R--VTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMS- 436 G I+K P+ +H + P + ++V DA T + +++ Sbjct: 285 WGIAQGYITKM-PK-----------FVHVDTDPAVLGTFYFPLLSVVADAKTFMEQLIEV 332 Query: 437 -------KIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGR 489 K +ER E F Q +++ + E+ G + P ++ + +++V Sbjct: 333 LPGTSGFKAVRYQER-ENFRQATEFRAAWDGWVREQESGDGM-PASMFRAMAEVRKVQRP 390 Query: 490 HVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDG 549 I+ T +G H + + P +TS G +G G P A+GAQ+A+P S V G Sbjct: 391 EDIIVTDIGNHTLPMFGGAILQRPRRLVTSMAEGILGCGFPMALGAQLAEPNSRVFLGTG 450 Query: 550 DASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSH---THQLNPDFI 606 D + E AV+ PV ++ NE G W + H++ T +NPD++ Sbjct: 451 DGALYYHFNEFRVAVEHKLPVITMVFTNESYG--ANWTLM--NHQFGQNNWTEFMNPDWV 506 Query: 607 KLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSG 660 +A+A G G V++ ++ L+ + + P L+E+ V K + GG G Sbjct: 507 GIAKAFGAYGESVRETGDIAGALQRAIDSGKPALIEIPVSKTQGLASDPVGGVG 560 >4QQ8-A nrPDB Length = 583 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 150/572 (26%), Positives = 251/572 (43%), Gaps = 49/572 (8%) Query: 92 LTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYAR 151 +TGG++ + + V+ +FG G I ++ A + D + +HE AGH AEGYAR Sbjct: 4 ITGGELVVRTLIKAGVEHLFGLHGIHIDTIFQACLDHD-VPIIDTRHEAAAGHAAEGYAR 62 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEA-DVVGIS 210 A K GV LVT+G G TN VTP+A+A D P++ TG T+ Q D V ++ Sbjct: 63 AGAKLGVALVTAGGGFTNAVTPIANARTDRTPVLFLTGSGALRDDETNTLQAGIDQVAMA 122 Query: 211 RSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPS 270 TKW V + E +P + +A A S GPVL+DLP D IL N I + + Sbjct: 123 APITKWAHRVMATEHIPRLVMQAIRAALSAPRGPVLLDLPWD----ILMNQIDEDSVIIP 178 Query: 271 NALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIP 330 + + D +++A L+ A++PV+ +G ++ R ++ + A + Sbjct: 179 DLVLSAHGAHPDP---ADLDQALALLRKAERPVIVLG------SEASRTARKTALSAFVA 229 Query: 331 VTTTLQGLGSFDQEDPKSLDML-----GMHGCATANL-----AVQNADLIIAVGARFDDR 380 T G+ F D + L ML M G NL A DL++ +GARF Sbjct: 230 AT----GVPVF--ADYEGLSMLSGLPDAMRGGLVQNLYSFAKADAAPDLVLMLGARFGLN 283 Query: 381 VTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTN---LGKMMSK 437 + P + + +I + + ++ + + D L + ++ Sbjct: 284 TGHGSGQLIPHSAQ--------VIQVDPDACELGRLQGIALGIVADVGGTIEALAQATAQ 335 Query: 438 IFPVKERSEWFAQINKWKKE-YPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTG 496 +R +W A++ +E Y + + + P + ++K D G V+ G Sbjct: 336 DAAWPDRGDWCAKVTDLAQERYASIAAKSSSEHALHPFHASQVIAKHV-DAGVTVVADGG 394 Query: 497 VGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPES--LVIDIDGDASFN 554 + +W ++ + P F+ G L +MG G A+GAQVA E+ I + GD S Sbjct: 395 L--TYLWLSEVMSRVKPGGFLCHGYLNSMGVGFGTALGAQVADLEAGRRTILVTGDGSVG 452 Query: 555 MTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFY-EHRYSHTHQLNPDFIKLAEAMG 613 ++ E + V+ P+ ++I+NN+ G +Q L +R + T N + +A A G Sbjct: 453 YSIGEFDTLVRKQLPLIVIIMNNQSWGWTLHFQQLAVGPNRVTGTRLENGSYHGVAAAFG 512 Query: 614 LKGLRVKKQEELDAKLKEFVSTKGPVLLEVEV 645 G V E A L + ++ P + V V Sbjct: 513 ADGYHVDSVESFSAALAQALAHNRPACINVAV 544 >1UPC-A nrPDB Length = 573 Score = 132 bits (333), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 146/544 (26%), Positives = 238/544 (43%), Gaps = 56/544 (10%) Query: 129 DKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFT 188 + +FVL +HE AG A+ AR +G+P T GPG TN+ T +A + D P++ Sbjct: 47 EGIDFVLTRHEFTAGVAADVLARITGRPQACWATLGPGMTNLSTGIATSVLDRSPVIALA 106 Query: 189 GQVPTSAI-GTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLV 247 Q + I D Q D V I +K+ V ++ E+ ++ A A + GP + Sbjct: 107 AQSESHDIFPNDTHQCLDSVAIVAPMSKYAVELQRPHEITDLVDSAVNAAMTEPVGPSFI 166 Query: 248 DLPKDVTAAI--LRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLY 305 LP D+ + + +P P+N + D + + AA L+ AK PVL Sbjct: 167 SLPVDLLGSSEGIDTTVPNP---PANTPAKPVGVVADGWQKAADQAAA-LLAEAKHPVLV 222 Query: 306 VGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANL-AV 364 VGA + P + + L++R IPV TT G + + + N A+ Sbjct: 223 VGAAAIRSGAVPAI-RALAERLNIPVITTYIAKGVLPVGHELNYGAVTGYMDGILNFPAL 281 Query: 365 QN----ADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQ 420 Q DL++ VG + + P + E + I V+P I +V + Sbjct: 282 QTMFAPVDLVLTVGYDYAE-------DLRPSMWQKGIEKKTVRISPTVNP--IPRVYRPD 332 Query: 421 IAVEGD----------ATTNLG-KMMSKIFPVKER-SEWFAQINKWKKEYPYAYMEETPG 468 + V D AT + G K I P++ R +E+ A ET Sbjct: 333 VDVVTDVLAFVEHFETATASFGAKQRHDIEPLRARIAEFLAD-------------PETYE 379 Query: 469 SKIKPQTVIKKLSKV---ANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTM 525 ++ VI ++ V A + G IV+ +G + + P F+TS G + Sbjct: 380 DGMRVHQVIDSMNTVMEEAAEPGEGTIVSD-IGFFRHYGVLFARADQPFGFLTSAGCSSF 438 Query: 526 GYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQ 585 GYG+PAAIGAQ+A+P+ I GD F+ ++L + + P+ +++NN+ G++ Sbjct: 439 GYGIPAAIGAQMARPDQPTFLIAGDGGFHSNSSDLETIARLNLPIVTVVVNNDTNGLIEL 498 Query: 586 WQSLFYEHRYSHTHQL---NPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLE 642 +Q++ H SH + DF+ LAEA G+ R +EEL A L++ P L+E Sbjct: 499 YQNI--GHHRSHDPAVKFGGVDFVALAEANGVDATRATNREELLAALRKGAELGRPFLIE 556 Query: 643 VEVD 646 V V+ Sbjct: 557 VPVN 560 >2Q28-A nrPDB Length = 564 Score = 125 bits (313), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 141/583 (24%), Positives = 246/583 (42%), Gaps = 79/583 (13%) Query: 94 GGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNS--DKFNFVLPKHEQGAGHMAEGYAR 151 G I E + + N+DT++G G +PV D ++ + ++ +HEQ AG+ A Sbjct: 10 GMHIIVEALKQNNIDTIYGVVG---IPVTDMARHAQAEGIRYIGFRHEQSAGYAAAASGF 66 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDA--FQEADVVGI 209 + KPG+ L S PG N +T +A+A +G PM++ +G + + ++E D + Sbjct: 67 LTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMISGSSDRAIVDLQQGDYEELDQMNA 126 Query: 210 SRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTL- 268 ++ K V ++L + + A ++ SGRPG V +DLP +V AA + T + Sbjct: 127 AKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPGGVYLDLPANVLAATMEKDEALTTIVK 186 Query: 269 ---PSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSD 325 PS AL +S+ A L+ A++P++ +G G ++ L+E + Sbjct: 187 VENPSPALLPCP---------KSVTSAISLLAKAERPLIILGKGAA-YSQADEQLREFIE 236 Query: 326 RAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNI 385 AQIP G + P S A + A+ NAD+++ VGAR + + Sbjct: 237 SAQIPFLPMSMAKGILEDTHPLSA-------AAARSFALANADVVMLVGARLNWLLAHGK 289 Query: 386 SKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERS 445 +A + + I ++ P+ I+ + V GD +++ M++++ + Sbjct: 290 KGWAADTQ---------FIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAEL-----KQ 335 Query: 446 EWFAQINKWK------KEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGR--HVIVTTGV 497 F W+ K+ M E + +P LS V D R I Sbjct: 336 NTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAV-RDVLRENQDIYLVNE 394 Query: 498 GQHQMWAAQHWT-WRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMT 556 G + + A++ P + G G MG G+ AIGA V S V+ I+GD++F + Sbjct: 395 GANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTS-GSPVVAIEGDSAFGFS 453 Query: 557 LTELSSAVQAGTPVKILILNNEEQGMVTQWQ-------------SLFYEHRYSHTHQLNP 603 E+ + + PV I+I NN G + + L + RY Sbjct: 454 GMEIETICRYNLPVTIVIFNN---GGIYRGDGVDLSGAGAPSPTDLLHHARYD------- 503 Query: 604 DFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVD 646 KL +A G V +EL L + ++ P ++ V +D Sbjct: 504 ---KLMDAFRGVGYNVTTTDELRHALTTGIQSRKPTIINVVID 543 >2JI6-A nrPDB Length = 568 Score = 118 bits (296), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 141/577 (24%), Positives = 238/577 (41%), Gaps = 57/577 (9%) Query: 90 VGLTGG-QIFNEMMSRQNVDTVFGYPGGAILPVYDA--IHNSDKFNFVLPKHEQGAGHMA 146 V LT G + + + ++DT++G G +P+ + + D F +HEQ AG+ A Sbjct: 7 VELTDGFHVLIDALKMNDIDTMYGVVG---IPITNLARMWQDDGQRFYSFRHEQHAGYAA 63 Query: 147 EGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDA--FQEA 204 GKPGV L S PG N VT +A A + PM++ +G + ++E Sbjct: 64 SIAGYIEGKPGVCLTVSAPGFLNGVTSLAHATTNCFPMILLSGSSEREIVDLQQGDYEEM 123 Query: 205 DVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 D + ++R K + + S++++P+ I A A SGRPG V VDLP + Sbjct: 124 DQMNVARPHCKASFRINSIKDIPIGIARAVRTAVSGRPGGVYVDLPAKLFG--------- 174 Query: 265 KTTLPSNALNQLTSRAQDEFVMQ-----SINKAADLINLAKKPVLYVGAGILNHADGPRL 319 T+ N+L + D Q +I +AADLI AK+PV+ +G G +A Sbjct: 175 -QTISVEEANKLLFKPIDPAPAQIPAEDAIARAADLIKNAKRPVIMLGKGAA-YAQCDDE 232 Query: 320 LKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDD 379 ++ L + IP G P+S AT A+ D+ + +GAR + Sbjct: 233 IRALVEETGIPFLPMGMAKGLLPDNHPQSAA-------ATRAFALAQCDVCVLIGARLNW 285 Query: 380 RVT-GNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKI 438 + G + E ++ I + + + N+ + + + + +L + K Sbjct: 286 LMQHGKGKTWGDELKKYVQ------IDIQANEMDSNQPIAAPVVGDIKSAVSLLRKALKG 339 Query: 439 FPVKERSEWF----AQINKWKKEYPYAYMEETPGSKIKPQT---VIKKLSKVANDTGRHV 491 P K +EW A+++ K + ETP + V++ D Sbjct: 340 AP-KADAEWTGALKAKVDGNKAKLAGKMTAETPSGMMNYSNSLGVVRDFMLANPDISLVN 398 Query: 492 IVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQ--VAKPESLVIDIDG 549 + +M P + SG G MG G+ + A KP VI ++G Sbjct: 399 EGANALDNTRMIV----DMLKPRKRLDSGTWGVMGIGMGYCVAAAAVTGKP---VIAVEG 451 Query: 550 DASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLA 609 D++F + EL + + PV ++I+NN G+ ++ S T + + Sbjct: 452 DSAFGFSGMELETICRYNLPVTVIIMNN--GGIYKGNEADPQPGVISCTRLTRGRYDMMM 509 Query: 610 EAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVD 646 EA G KG EL A L+E V++ P L+ +D Sbjct: 510 EAFGGKGYVANTPAELKAALEEAVASGKPCLINAMID 546 >4Q9D-A nrPDB Length = 545 Score = 105 bits (262), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 127/565 (22%), Positives = 229/565 (40%), Gaps = 53/565 (9%) Query: 100 EMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVV 159 +++ + + TVFG PG + F +VL E A MA+G+A+A+GKP +V Sbjct: 13 DLLRKLGLTTVFGNPGSTEESFLRDF--PEDFTYVLSLQEASALAMADGFAQATGKPALV 70 Query: 160 LVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAF-QEADVVGISRSCTKWNV 218 + + G N + + A+ P+++ GQ D + D + + KW+ Sbjct: 71 NLHTAAGTGNAMGSLVAAYRANTPLIITAGQQTREMSVVDPYLNNPDATTMPKPWVKWSY 130 Query: 219 MVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTS 278 E++P +A+ +A GPV + +P D K L A+ +++ Sbjct: 131 EPARAEDVPAAFMQAYAVAMQPPMGPVFLSIPLDDW---------DKPALGPAAVRSVST 181 Query: 279 RAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPV-TTTLQG 337 R + + + + A+ IN AK P+L +G + + A E +++ PV + L Sbjct: 182 RVAPD--AERLAQFAERINAAKHPMLVLGPEV-DRAGAWDAGIEFAEKLGAPVHASALPD 238 Query: 338 LGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGA---RFDDRVTGNISKFAPEARR 394 SF ++ P L M A AV DL++ VGA R+ V G ++ PE Sbjct: 239 RMSFPEDHPLYAGPLPMT-IAGVEQAVSAYDLVVVVGAEVFRYYPYVPG---EYLPEGTD 294 Query: 395 AAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKW 454 ++ P + V ++ GD L ++ I +R + + Sbjct: 295 --------LLQITADPHR-SAVAPVGDSLVGDVGIALSRLTELIDTPDDRVPPKPLVRQR 345 Query: 455 KKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTW---R 511 + P + + V + LS V D V+ +T +TW Sbjct: 346 HSDIPST-------APMTSNAVYEVLSNVKPDDAAVVMESTST------MLDLFTWLPTT 392 Query: 512 NPHTFITSGGLGTMGYGLPAAIGAQVAKP----ESLVIDIDGDASFNMTLTELSSAVQAG 567 +P +F +G G +G+G+PAA+G + + V+ GD SF ++ + +A Q Sbjct: 393 HPASFFATGS-GGIGWGVPAAVGIALGDRARGVDRTVVATIGDGSFQYSIQAIWTAAQHK 451 Query: 568 TPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDA 627 P+ ++L N E ++ + L D +A G + V+ + L+A Sbjct: 452 LPIVFVVLRNGEYAILKSFADLEKTPNVPGLQLPGLDISSIAAGFGCRTATVESTDMLEA 511 Query: 628 KLKEFVSTKGPVLLEVEVDKKVPVL 652 +LK + GP +L V ++P L Sbjct: 512 ELKTALQADGPTVLVVPTLPQLPQL 536 >2VBF-A nrPDB Length = 570 Score = 99.0 bits (245), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 113/497 (22%), Positives = 212/497 (42%), Gaps = 53/497 (10%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G + + ++ +FG PG L D I + + ++ +E A +MA+GYAR Sbjct: 26 TVGDYLLDRLHELGIEEIFGVPGDYNLQFLDQIISREDMKWIGNANELNASYMADGYAR- 84 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDA--FQEADVVGIS 210 + K L T G G + + +A ++A+ +P+V G PTS + D G Sbjct: 85 TKKAAAFLTTFGVGELSAINGLAGSYAENLPVVEIVGS-PTSKVQNDGKFVHHTLADGDF 143 Query: 211 RSCTKWNVMVKSVEELPLRINEAFEI-----ATSGRPGPVLVDLPKDVTAAILRNPIPTK 265 + K + V + L N +EI PV ++LP DV AA P + Sbjct: 144 KHFMKMHEPVTAARTLLTAENATYEIDRVLSQLLKERKPVYINLPVDVAAAKAEKPALSL 203 Query: 266 TTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSD 325 S T+ ++ ++ I ++ + A+KPV+ G +++ + + + Sbjct: 204 EKESS------TTNTTEQVILSKIEES---LKNAQKPVVIAGHEVISFG-LEKTVTQFVS 253 Query: 326 RAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQN----ADLIIAVGARFDDRV 381 ++P+TT G + D+ P LG++ + ++++N AD I+ +G + D Sbjct: 254 ETKLPITTLNFGKSAVDESLPS---FLGIYNGKLSEISLKNFVESADFILMLGVKLTDSS 310 Query: 382 TGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPV 441 TG + E + + GII NKVV+ + ++S + + Sbjct: 311 TGAFTHHLDENKMISLNIDEGII--------FNKVVED---------FDFRAVVSSLSEL 353 Query: 442 KERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQ 501 K I+K +E+ + P S+ + ++ L++ +N+T ++ G Sbjct: 354 KGIEYEGQYIDKQYEEFIPS---SAPLSQDRLWQAVESLTQ-SNET---IVAEQGTS--- 403 Query: 502 MWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELS 561 + A ++ FI G++GY PAA+G+Q+A ES + GD S +T+ EL Sbjct: 404 FFGASTIFLKSNSRFIGQPLWGSIGYTFPAALGSQIADKESRHLLFIGDGSLQLTVQELG 463 Query: 562 SAVQAGTPVKILILNNE 578 +++ I+NN+ Sbjct: 464 LSIREKLNPICFIINND 480 >1OVM-A nrPDB Length = 552 Score = 91.3 bits (225), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 137/574 (23%), Positives = 226/574 (39%), Gaps = 80/574 (13%) Query: 100 EMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVV 159 + ++ D +FG PG L D + +S +V +E A + A+GYAR G + Sbjct: 13 DRLTDCGADHLFGVPGDYNLQFLDHVIDSPDICWVGCANELNASYAADGYARCKGF-AAL 71 Query: 160 LVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVV------GISRSC 213 L T G G + + +A ++A+ +P++ G A GT A Q +++ G R Sbjct: 72 LTTFGVGELSAMNGIAGSYAEHVPVLHIVG-----APGTAAQQRGELLHHTLGDGEFRHF 126 Query: 214 TKWNVMVKSVEELPLRINEAFEI-------ATSGRPGPVLVDLPKDVTAAILRNPIPTKT 266 + + + + N +EI RPG ++ LP DV Sbjct: 127 YHMSEPITVAQAVLTEQNACYEIDRVLTTMLRERRPGYLM--LPADVA--------KKAA 176 Query: 267 TLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDR 326 T P NAL + A + + A + + ++K+ L +L H L K + Sbjct: 177 TPPVNALTHKQAHADSACLKAFRDAAENKLAMSKRTALLADFLVLRHGLKHALQKWVK-- 234 Query: 327 AQIPV--TTTLQGLGSFDQEDPKSLDML-GMHGCATANLAVQNADLIIAVGARFDDRVTG 383 ++P+ T L G G FD+ G A++ AD ++ VG RF D +T Sbjct: 235 -EVPMAHATMLMGKGIFDERQAGFYGTYSGSASTGAVKEAIEGADTVLCVGTRFTDTLTA 293 Query: 384 NISKFAPEARRAAAE---GRGGIIHFEVSPKNINKVVQTQIAV-EGDATTNLGKMMSKIF 439 + A+ + R G + F P +N+ ++T + + + L S Sbjct: 294 GFTHQLTPAQTIEVQPHAARVGDVWFTGIP--MNQAIETLVELCKQHVHAGLMSSSSGAI 351 Query: 440 PVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQ 499 P + Q N W+ QT I+ + D G T+ G Sbjct: 352 PFPQPDGSLTQENFWRTL----------------QTFIRPGDIILADQG-----TSAFGA 390 Query: 500 HQMWAAQHWTWRNPH--TFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTL 557 + R P FI G++GY L AA GAQ A P VI + GD + +T+ Sbjct: 391 IDL--------RLPADVNFIVQPLWGSIGYTLAAAFGAQTACPNRRVIVLTGDGAAQLTI 442 Query: 558 TELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGL--- 614 EL S ++ IL+LNNE G + E RY+ N + + +A+ L Sbjct: 443 QELGSMLRDKQHPIILVLNNE--GYTVERAIHGAEQRYNDIALWN--WTHIPQALSLDPQ 498 Query: 615 -KGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDK 647 + RV + E+L L++ + L+EV + K Sbjct: 499 SECWRVSEAEQLADVLEKVAHHERLSLIEVMLPK 532 >2Q5O-A nrPDB Length = 565 Score = 89.7 bits (221), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 124/558 (22%), Positives = 215/558 (38%), Gaps = 54/558 (9%) Query: 102 MSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLV 161 + + +FG PG LP + + HE G A+ AR S GV V Sbjct: 31 LKDRGAQAMFGIPGDFALPFFKVAEETQILPLHTLSHEPAVGFAADAAARYSSTLGVAAV 90 Query: 162 TSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAF------QEADV-VGISRSCT 214 T G GA N+V +A A+A+ P+VV +G P + G + D + + T Sbjct: 91 TYGAGAFNMVNAVAGAYAEKSPVVVISG-APGTTEGNAGLLLHHQGRTLDTQFQVFKEIT 149 Query: 215 KWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALN 274 + + P I A + PV +++P+++ A + P+ P + Sbjct: 150 VAQARLDDPAKAPAEIARVLG-AARAQSRPVYLEIPRNMVNAEV-EPVGDDPAWPVD--R 205 Query: 275 QLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTT 334 + DE V+ ++ A PVL V + + ++ EL+ R +PV TT Sbjct: 206 DALAACADE-VLAAMRSA-------TSPVLMVCVEVRRYGLEAKV-AELAQRLGVPVVTT 256 Query: 335 LQGLGSF-DQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEAR 393 G G D P +G+ G A V+ +D + +GA D + FA R Sbjct: 257 FMGRGLLADAPTPPLGTYIGVAGDAEITRLVEESDGLFLLGAILSD------TNFAVSQR 310 Query: 394 RAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDA-TTNLGKMMSKIFPVKERSEWFAQIN 452 + I + ++ V D L + + P +R+ Sbjct: 311 K---------IDLRKTIHAFDRAVTLGYHTYADIPLAGLVDALLERLPPSDRT------T 355 Query: 453 KWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRN 512 + K+ + Y + G I P + + ++ +++ +G A Sbjct: 356 RGKEPHAYPTGLQADGEPIAPMDIARAVNDRVRAGQEPLLIAADMGDCLFTAMDMID--- 412 Query: 513 PHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKI 572 + G MG+G+PA IGAQ ++ + GD +F MT EL + + G + Sbjct: 413 -AGLMAPGYYAGMGFGVPAGIGAQCVSGGKRILTVVGDGAFQMTGWELGNCRRLGIDPIV 471 Query: 573 LILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEF 632 ++ NN M+ +Q E ++ F +A MG G+RV+ + EL A L + Sbjct: 472 ILFNNASWEMLRTFQP---ESAFNDLDDWR--FADMAAGMGGDGVRVRTRAELKAALDKA 526 Query: 633 VSTKGPV-LLEVEVDKKV 649 +T+G L+E + + V Sbjct: 527 FATRGRFQLIEAMIPRGV 544 >4K9Q-A nrPDB Length = 539 Score = 89.4 bits (220), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 128/577 (22%), Positives = 234/577 (40%), Gaps = 71/577 (12%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T +I +++ + V TV G PG + + SD FN+VL E +A+G +++ Sbjct: 3 TVKEITFDLLRKLQVTTVVGNPG-STEETFLKDFPSD-FNYVLALQEASVVAIADGLSQS 60 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAF-QEADVVGISR 211 KP +V + +G G N + + A+ + P+++ GQ + + + + + + Sbjct: 61 LRKPVIVNIHTGAGLGNAMGCLLTAYQNKTPLIITAGQQTREMLLNEPLLTNIEAINMPK 120 Query: 212 SCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSN 271 KW+ E++P A+ A GPV + LP D ++ +T Sbjct: 121 PWVKWSYEPARPEDVPGAFMRAYATAMQQPQGPVFLSLPLDDWEKLIPEVDVARTVS--- 177 Query: 272 ALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNH---ADGPRLLKELSDRAQ 328 T + D + + A I +K P+L G+ I +DG ++R Sbjct: 178 -----TRQGPDP---DKVKEFAQRITASKNPLLIYGSDIARSQAWSDG----IAFAERLN 225 Query: 329 IPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLA-----VQNADLIIAVGA---RFDDR 380 PV F + P D G T+ + +Q DLI+ +GA R+ Sbjct: 226 APVWA-----APFAERTPFPEDHPLFQGALTSGIGSLEKQIQGHDLIVVIGAPVFRYYPW 280 Query: 381 VTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKM--MSKI 438 + G +F PE ++ P +K AV GD+ + K+ + + Sbjct: 281 IAG---QFIPEGST--------LLQVSDDPNMTSK------AVVGDSLVSDSKLFLIEAL 323 Query: 439 FPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVG 498 + +R + N + P + T ++P V++ L + ++ + +++ Sbjct: 324 KLIDQREK-----NNTPQRSPMTKEDRT-AMPLRPHAVLEVLKE---NSPKEIVLVEECP 374 Query: 499 QHQMWAAQHWTWRNPHTFIT--SGGLGTMGYGLPAAIG----AQVAKPESLVIDIDGDAS 552 + P TF T SGGLG + LPAA+G +V+ V+ + GD S Sbjct: 375 SIVPLMQDVFRINQPDTFYTFASGGLG---WDLPAAVGLALGEEVSGRNRPVVTLMGDGS 431 Query: 553 FNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAM 612 F ++ + + VQ T V ++ NEE G++ Q+ L D + +A Sbjct: 432 FQYSVQGIYTGVQQKTHVIYVVFQNEEYGILKQFAELEQTPNVPGLDLPGLDIVAQGKAY 491 Query: 613 GLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 649 G K L+V+ +EL E +S KG ++ V + K++ Sbjct: 492 GAKSLKVETLDELKTAYLEALSFKGTSVIVVPITKEL 528 >1QPB-A nrPDB Length = 563 Score = 85.9 bits (211), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 128/513 (24%), Positives = 206/513 (40%), Gaps = 70/513 (13%) Query: 92 LTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYAR 151 +T G+ E + + NV+TVFG PG L + D I+ + + +E A + A+GYAR Sbjct: 4 ITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYAR 63 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSA----------IGTDAF 201 G ++ T G G + + +A ++A+ + ++ G SA +G F Sbjct: 64 IKGM-SCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISAQAKQLLLHHTLGNGDF 122 Query: 202 QEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPK-----DVTAA 256 +S + ++ M+ + P I+ T PV + LP +V A Sbjct: 123 TVFH--RMSANISETTAMITDIATAPAEIDRCIR-TTYVTQRPVYLGLPANLVDLNVPAK 179 Query: 257 ILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADG 316 +L+ PI P++A E + I+ LI AK PV+ A H D Sbjct: 180 LLQTPIDMSLK-PNDA----------ESEKEVIDTILVLIKDAKNPVILADACCSRH-DV 227 Query: 317 PRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDM-LGMHGCATANLAVQNADLIIAVGA 375 K+L D Q P T G GS D++ P+ + +G AV++ADLI++VGA Sbjct: 228 KAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAVESADLILSVGA 287 Query: 376 RFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMM 435 D TG+ S + KNI + + + T G M Sbjct: 288 LLSDFNTGSFS-------------------YSYKTKNIVEFHSDHMKIRN--ATFPGVQM 326 Query: 436 SKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRH----- 490 F +++ A K K P A TP + P + K + N G Sbjct: 327 K--FVLQKLLTAIADAAKGYK--PVAVPARTPANAAVPASTPLKQEWMWNQLGNFLQEGD 382 Query: 491 -VIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVA----KPESLVI 545 VI TG + T+ N I+ G++G+ A +GA A P+ VI Sbjct: 383 VVIAETGTSA---FGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVI 439 Query: 546 DIDGDASFNMTLTELSSAVQAGTPVKILILNNE 578 GD S +T+ E+S+ ++ G + +LNN+ Sbjct: 440 LFIGDGSLQLTVQEISTMIRWGLKPYLFVLNND 472 >6EFG-A nrPDB Length = 563 Score = 82.8 bits (203), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 122/508 (24%), Positives = 206/508 (40%), Gaps = 60/508 (11%) Query: 92 LTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYAR 151 +T G+ E + + V T+FG PG L + D I+ + +E A + A+GYAR Sbjct: 4 ITLGRYLFERLKQVEVQTIFGLPGDFNLSLLDNIYEVPGMRWAGNANELNAAYAADGYAR 63 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVG--- 208 G ++ T G G + + +A ++A+ + ++ VP+ + +G Sbjct: 64 LKGM-SCIITTFGVGELSALNGIAGSYAEHVGVLH-VVGVPSVSSQAKQLLLHHTLGNGD 121 Query: 209 ------ISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKD-----VTAAI 257 +S + ++ M+ + P I+ T PV + LP + V A++ Sbjct: 122 FTVFHRMSSNISETTAMITDINTAPAEIDRCIR-TTYVSQRPVYLGLPANLVDLTVPASL 180 Query: 258 LRNPIPTKTTLPSNALNQLTSRAQD-EFVMQSINKAADLINLAKKPVLYVGAGILNHADG 316 L PI L+ + D E + I LI AK PV+ A H D Sbjct: 181 LDTPI------------DLSLKPNDPEAEEEVIENVLQLIKEAKNPVILADACCSRH-DA 227 Query: 317 PRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDM-LGMHGCATANLAVQNADLIIAVGA 375 K+L D Q P T G GS D++ P+ + +G AV++ADL+++VGA Sbjct: 228 KAETKKLIDLTQFPAFVTPMGKGSIDEKHPRFGGVYVGTLSSPAVKEAVESADLVLSVGA 287 Query: 376 RFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKV----VQTQIAVEGDATTNL 431 D TG+ S ++ + + I+ F I VQ + A++ T + Sbjct: 288 LLSDFNTGSFS-YSYKTKN--------IVEFHSDYTKIRSATFPGVQMKFALQ-KLLTKV 337 Query: 432 GKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHV 491 PV SE E+ A + TP +K + V ++ + + G V Sbjct: 338 ADAAKGYKPVPVPSE---------PEHNEAVADSTP---LKQEWVWTQVGEFLRE-GDVV 384 Query: 492 IVTTGVGQHQMWAAQHWTWRNPHTFITSGGLG-TMGYGLPAAIGAQVAKPESLVIDIDGD 550 I TG + + + G +G T G L AA A+ P+ VI GD Sbjct: 385 ITETGTSAFGINQTHFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILFIGD 444 Query: 551 ASFNMTLTELSSAVQAGTPVKILILNNE 578 S +T+ E+S+ ++ G + +LNN+ Sbjct: 445 GSLQLTVQEISTMIRWGLKPYLFVLNND 472 >5NPU-A nrPDB Length = 563 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 132/590 (22%), Positives = 225/590 (38%), Gaps = 90/590 (15%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G +++ + F G L + D + + V +E G AEGYARA Sbjct: 4 TVGHYLATRLAQIGLKHHFAVAGDYNLVLLDQLLKNKDLEQVYCCNELNCGFSAEGYARA 63 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADV------ 206 +G G +VT GA + + A+A+ +P+++ +G T+ G+ + Sbjct: 64 NGV-GAAVVTFSVGALSAFNAIGGAYAENLPVILISGAPNTNDHGSGHILHHTIGTTDYG 122 Query: 207 --VGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 + +++ T V + E+ P I+ A A + P +++ +V A P P Sbjct: 123 YQLEMAKQITCAAVSITHAEDAPALIDHAIRTALREKK-PAYIEIACNVAAQPCARPGPV 181 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 S LN+ TS +E + ++ A D I +KPVL VG G L A + EL+ Sbjct: 182 -----SALLNEPTS--DEETLKAAVEAALDFIEKREKPVLLVG-GKLRAAGAEEAVVELA 233 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQN----ADLIIAVGARFDDR 380 D V T F ++ P +G + ++ V+ AD II +G F+D Sbjct: 234 DALGCAVATMAAAKSFFPEDHP---GYVGTYWGEVSSPGVEEIVDWADGIICLGPVFNDY 290 Query: 381 VT---------GNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNL 431 T N+ P E G IH + + + V + A + Sbjct: 291 STVGWTAWPKGENVVLVDPHHITVGGEEFTG-IHLKDFLTALTERVPKKDATLDQFKARV 349 Query: 432 GKMMSKIFPVKE------RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVAN 485 GK ++ P + R+E QI + P T + + + Sbjct: 350 GKPAAEKVPAADPNAPLTRAELCRQIQ----------------GLLNPNTTLIAETGDSW 393 Query: 486 DTGRHVIVTTG--VGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESL 543 + + G V W H W P TF G VA+PE Sbjct: 394 FNAMRMKLPHGARVELEMQWG--HIGWSVPATF-----------------GYAVAEPERR 434 Query: 544 VIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNP 603 + + GD SF +T E++ V+ P+ I ++NN +G + + H + + N Sbjct: 435 NVLMVGDGSFQLTAQEVAQMVRRKLPIIIFLINN--RGYTIEVKI----HDGPYNNIKNW 488 Query: 604 DFIKLAEAMGLK-----GLRVKKQEELDAKLKEFVSTK-GPVLLEVEVDK 647 D+ L E + GL+ EL +K+ ++ + GP L+E +D+ Sbjct: 489 DYAGLMEVFNAEDGKGLGLKATTGGELAEAIKKALAHREGPTLIECVIDR 538 >4ZP1-A nrPDB Length = 568 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 123/542 (22%), Positives = 217/542 (40%), Gaps = 71/542 (13%) Query: 134 VLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTG---- 189 V +E G AEGYARA G V VT GA + + A+A+ +P+++ +G Sbjct: 45 VYCCNELNCGFSAEGYARAKGAAAAV-VTYSVGALSAFDAIGGAYAENLPVILISGAPNN 103 Query: 190 ------QVPTSAIG-TDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRP 242 V A+G TD + + ++++ T + + EE P +I+ + A + Sbjct: 104 NDHAAGHVLHHALGKTDYHYQLE---MAKNITAAAEAIYTPEEAPAKIDHVIKTALREKK 160 Query: 243 GPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQS-INKAADLINLAKK 301 PV +++ ++ + +P P++AL A DE + + + + I K Sbjct: 161 -PVYLEIACNIAS------MPCAAPGPASAL--FNDEASDEASLNAAVEETLKFIANRDK 211 Query: 302 PVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDM-LGMHGCATA 360 + VG+ L A + +D V T F +E+P + G Sbjct: 212 VAVLVGSK-LRAAGAEEAAVKFADALGGAVATMAAAKSFFPEENPHYIGTSWGEVSYPGV 270 Query: 361 NLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQ 420 ++ AD +IA+ F+D T + + AE R ++ N + Sbjct: 271 EKTMKEADAVIALAPVFNDYSTTGWTDIPDPKKLVLAEPRSVVV---------NGIRFPS 321 Query: 421 IAVEGDATTNLGKMMSKIFPVKERSEWFAQIN--KWKKEYPYAYMEETPGSKIKPQTVIK 478 + ++ D T L + +SK ++F +N + KK P P + + + + Sbjct: 322 VHLK-DYLTRLAQKVSK---KTGALDFFKSLNAGELKKAAP-----ADPSAPLVNAEIAR 372 Query: 479 KLSKVA--NDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQ 536 ++ + N T VI TG + AQ N G +G+ +PAA G Sbjct: 373 QVEALLTPNTT---VIAETG---DSWFNAQRMKLPNGARVEYEMQWGHIGWSVPAAFGYA 426 Query: 537 VAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYS 596 V PE I + GD SF +T E++ V+ PV I ++NN + + ++ Y+ Sbjct: 427 VGAPERRNILMVGDGSFQLTAQEVAQMVRLKLPVIIFLINNYGYTIAV----MIHDGPYN 482 Query: 597 HTHQLNPDFIKLAEAM---------GLKGLRVKKQEELDAKLK-EFVSTKGPVLLEVEVD 646 + N D+ L E KGL+ K EL +K +T GP L+E + Sbjct: 483 NIK--NWDYAGLMEVFNGNGGYDSGAGKGLKAKTGGELAEAIKVALANTDGPTLIECFIG 540 Query: 647 KK 648 ++ Sbjct: 541 RE 542 >4COK-A nrPDB Length = 558 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 14/132 (10%) Query: 523 GTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGM 582 G +G+ +PAA G +A PE + + GD SF +T E++ ++ PV I ++NN + Sbjct: 409 GHIGWSVPAAFGNALAAPERQHVLMVGDGSFQLTAQEVAQMIRHDLPVIIFLINNHGYTI 468 Query: 583 VTQWQSLFYEHRYSHTHQLNPDFIKLAEAM------GLKGLRVKKQEELDAKLKEFVSTK 636 + + ++ Y++ N D+ L E GL GLR + EL A +++ + + Sbjct: 469 ----EVMIHDGPYNNVK--NWDYAGLMEVFNAGEGNGL-GLRARTGGELAAAIEQARANR 521 Query: 637 -GPVLLEVEVDK 647 GP L+E +D+ Sbjct: 522 NGPTLIECTLDR 533 >5EUJ-A nrPDB Length = 573 Score = 52.0 bits (123), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 38/141 (26%), Positives = 68/141 (48%), Gaps = 10/141 (7%) Query: 523 GTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGM 582 G +G+ +P+A G V PE I + GD SF +T E++ ++ PV I ++NN +G Sbjct: 408 GHIGWSVPSAFGNAVGSPERRHIMMVGDGSFQLTAQEVAQMIRYEIPVIIFLINN--RGY 465 Query: 583 VTQWQSLFYEHRYSHTHQLNP----DFIKLAEAMGLKGLRVKKQEELDAKLKEFVST-KG 637 V + ++ Y++ N D + GL GL+ EL+ +K+ + +G Sbjct: 466 VI--EIAIHDGPYNYIKNWNYAGLIDVFNDEDGHGL-GLKASTGAELEGAIKKALDNRRG 522 Query: 638 PVLLEVEVDKKVPVLPMVAGG 658 P L+E + + ++A G Sbjct: 523 PTLIECNIAQDDCTETLIAWG 543 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 66/263 (25%), Positives = 110/263 (41%), Gaps = 29/263 (11%) Query: 134 VLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPT 193 V +E G AEGYARA G + VT GA + + + A+A+ +P+++ +G T Sbjct: 44 VYCCNELNCGFSAEGYARARGAAAAI-VTFSVGAISAMNAIGGAYAENLPVILISGSPNT 102 Query: 194 SAIGTDAFQEADVVGISRSCTKWNV---MVK----------SVEELPLRINEAFEIATSG 240 + GT ++ + T +N MVK S EE P +I+ A Sbjct: 103 NDYGT-----GHILHHTIGTTDYNYQLEMVKHVTCAAESIVSAEEAPAKIDHVIRTALRE 157 Query: 241 RPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAK 300 R P +++ +V A P P + L ++Q + V +++ A + + + Sbjct: 158 RK-PAYLEIACNVAGAECVRPGPINSLLRELEVDQTS-------VTAAVDAAVEWLQDRQ 209 Query: 301 KPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDML-GMHGCAT 359 V+ VG+ L A + L+DR VT G F ++ P + G Sbjct: 210 NVVMLVGSK-LRAAAAEKQAVALADRLGCAVTIMAAAKGFFPEDHPNFRGLYWGEVSSEG 268 Query: 360 ANLAVQNADLIIAVGARFDDRVT 382 A V+NAD I+ + F+D T Sbjct: 269 AQELVENADAILCLAPVFNDYAT 291 >2VBI-A nrPDB Length = 566 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 37/133 (27%), Positives = 65/133 (48%), Gaps = 16/133 (12%) Query: 523 GTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGM 582 G +G+ +P+A G + + + + GD SF +T E++ V+ PV I ++NN +G Sbjct: 409 GHIGWSVPSAFGNAMGSQDRQHVVMVGDGSFQLTAQEVAQMVRYELPVIIFLINN--RGY 466 Query: 583 VTQWQSLFYEHRYSHTHQLNPDFIKLAE--------AMGLKGLRVKKQEELDAKLKEFVS 634 V + H + + N D+ L E +GLK K+ E A+ K + Sbjct: 467 VIE----IAIHDGPYNYIKNWDYAGLMEVFNAGEGHGLGLKATTPKELTEAIARAK--AN 520 Query: 635 TKGPVLLEVEVDK 647 T+GP L+E ++D+ Sbjct: 521 TRGPTLIECQIDR 533 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 53/257 (20%), Positives = 107/257 (41%), Gaps = 25/257 (9%) Query: 138 HEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIG 197 +E G AEGYAR++G V VT GA + + + A+A+ +P+++ +G ++ G Sbjct: 49 NELNCGFSAEGYARSNGAAAAV-VTFSVGAISAMNALGGAYAENLPVILISGAPNSNDQG 107 Query: 198 TDAFQEADV--------VGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDL 249 T + + ++R T + P +I+ A R P +D+ Sbjct: 108 TGHILHHTIGKTDYSYQLEMARQVTCAAESITDAHSAPAKIDHVIRTALRERK-PAYLDI 166 Query: 250 PKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAG 309 ++ + P P + L ++ + +A +++ L+ + PV+ +G+ Sbjct: 167 ACNIASEPCVRPGPVSSLLSEPEIDHTSLKA-------AVDATVALLEKSASPVMLLGSK 219 Query: 310 ILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQ---- 365 L A+ + L+D+ Q VT G F ++ G++ +N VQ Sbjct: 220 -LRAANALAATETLADKLQCAVTIMAAAKGFFPEDHA---GFRGLYWGEVSNPGVQELVE 275 Query: 366 NADLIIAVGARFDDRVT 382 +D ++ + F+D T Sbjct: 276 TSDALLCIAPVFNDYST 292 >3LQ1-A nrPDB Length = 578 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 41/131 (31%), Positives = 59/131 (45%), Gaps = 14/131 (10%) Query: 139 EQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGT 198 E+ AG A G A+AS +P V+L TSG A N +A+A IP++V T P Sbjct: 58 ERSAGFFALGLAKASKRPVVLLCTSGTAAANYFPAVAEANLSQIPLIVLTADRPHELRNV 117 Query: 199 DAFQEADVVGISRSCTK--WNVMVKSVEELPLRI-----NEAFEIATSGRPGPVLVDLPK 251 A Q D + + S K ++ + E LR + A +IA GPV ++ P Sbjct: 118 GAPQAMDQLHLYGSHVKDFTDMALPENSEEMLRYAKWHGSRAVDIAMKTPRGPVHLNFP- 176 Query: 252 DVTAAILRNPI 262 LR P+ Sbjct: 177 ------LREPL 181 >2JLA-A nrPDB Length = 558 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 49/118 (41%) Query: 85 MDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGH 144 M S + E ++R V + PG P+ A + F E+G GH Sbjct: 3 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGH 62 Query: 145 MAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQ 202 +A G A+ S +P V+VTSG N+ + +A G +++ T P I A Q Sbjct: 63 LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQ 120 >5ESS-A nrPDB Length = 574 Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 24/187 (12%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFV---LPKHEQGAGHMAEGY 149 T ++ + + R V V PG P+ A+ ++D+ + + E+ AG++A G Sbjct: 26 TQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGYLAIGL 85 Query: 150 ARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGI 209 A +G P V +TSG N+ + +A +P++V + P +GT A Q + +G Sbjct: 86 AIGAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTMEQLGY 145 Query: 210 SRSCTKWNVMVKSVEELPLR---INEAFEIAT-----------SGRPGPVLVDLPKDVTA 255 + + ++ + E+ P R +N + AT + GPV D+P Sbjct: 146 FGTQVRASISLGLAEDAPERTSALNATWRSATCRVLAAATGARTANAGPVHFDIP----- 200 Query: 256 AILRNPI 262 LR P+ Sbjct: 201 --LREPL 205 >2X7J-A nrPDB Length = 604 Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 29/54 (53%) Query: 139 EQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVP 192 E+ AG A G A+A +P +++ TSG A N + +A +P++V T P Sbjct: 78 ERSAGFFALGLAKAKQRPVLLICTSGTAAANFYPAVVEAHYSRVPIIVLTADRP 131 Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 3/45 (6%) Query: 540 PESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVT 584 P +LVI GD SF L L +A + G P+ ++++NN+ G+ + Sbjct: 474 PVTLVI---GDLSFYHDLNGLLAAKKLGIPLTVILVNNDGGGIFS 515 >1MJG-A nrPDB Length = 674 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 23/162 (14%) Query: 54 RPEPAPSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLTGGQI-------FNEMMSRQN 106 R E + NV P A S+L + A MD V L I E ++ Sbjct: 194 RKEKFRTHNVVPFGIHASISELVNQ--AHMGMDNDPVNLVFSAIRVALADYTGEHIATDF 251 Query: 107 VDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHE--------QGAGHMAEGYARASGKPGV 158 D +FG P + + + D+ NFVL H Q A M EG A+A+G G+ Sbjct: 252 SDILFGTPQPVVSEANMGVLDPDQVNFVLHGHNPLLSEIIVQAAREM-EGEAKAAGAKGI 310 Query: 159 VLVTSGPGATNVV----TPMADAFADGIPMVVFTGQVPTSAI 196 LV V+ P+ +FA + + TG + + Sbjct: 311 NLVGICCTGNEVLMRQGIPLVTSFASQ-ELAICTGAIDAMCV 351 >4ZEN-A nrPDB Length = 485 Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust. Identities = 11/30 (36%), Positives = 19/30 (63%) Query: 320 LKELSDRAQIPVTTTLQGLGSFDQEDPKSL 349 L+ +++R Q+P+ T GLG FD +P + Sbjct: 370 LRRIANRYQLPILITENGLGEFDTLEPGDI 399 >1CJS-A nrPDB Length = 219 Score = 29.6 bits (65), Expect = 4.0, Method: Compositional matrix adjust. Identities = 33/143 (23%), Positives = 56/143 (39%), Gaps = 33/143 (23%) Query: 22 RNTPAMRSVALAQRFYSSSS-------RYYSASPLPASKRPEPAPS-FNVDPLEQPAEPS 73 +N +R +A A F+ + + RY P K P+P P+ N+ PL + Sbjct: 90 KNKRKLRKIAKAHDFFIAQADLMPLIGRYMGVILGPRGKMPKPVPANANIKPLVE----- 144 Query: 74 KLAKKLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNF 133 +L K + F L G + +M Q VD + +A+ N Sbjct: 145 RLKKTVVINTRDKPYFQVLVGNE---KMTDEQIVDNI------------EAV-----LNV 184 Query: 134 VLPKHEQGAGHMAEGYARASGKP 156 V K+E+G H+ + Y + + P Sbjct: 185 VAKKYEKGLYHIKDAYVKLTMGP 207 >3DC2-A nrPDB Length = 529 Score = 29.3 bits (64), Expect = 5.8, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 118 ILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADA 177 +L + D + +D + LPK + AG + + A A KPGV++V + G +ADA Sbjct: 187 LLSLDDLLARADFISVHLPKTPETAG-LIDKEALAKTKPGVIIVNAARGGLVDEAALADA 245 Query: 178 FADG 181 G Sbjct: 246 ITGG 249 >2O6L-A nrPDB Length = 170 Score = 28.9 bits (63), Expect = 6.8, Method: Compositional matrix adjust. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 6/70 (8%) Query: 147 EGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADV 206 E + ++SG+ GVV+ + G +N+ A+ A + Q+P + + D Sbjct: 12 EDFVQSSGENGVVVFSLGSMVSNMTEERANVIASAL------AQIPQKVLWRFDGNKPDT 65 Query: 207 VGISRSCTKW 216 +G++ KW Sbjct: 66 LGLNTRLYKW 75 >2I2W-A nrPDB Length = 212 Score = 28.9 bits (63), Expect = 8.3, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Query: 120 PVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLV---TSGPGATNVVTPMAD 176 P Y AI SD + ++ G + Y A G+ G VL+ TSG A NV+ +A Sbjct: 95 PGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSA-NVIKAIAA 153 Query: 177 AFADGIPMVVFTGQVPTSAIGT 198 A G+ ++ TG+ GT Sbjct: 154 AREKGMKVITLTGKDGGKMAGT 175 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1T9B-A nrPDB 811 0.0 6DEO-A nrPDB 766 0.0 5WJ1-A nrPDB 533 e-151 2PAN-A nrPDB 477 e-134 5AHK-A nrPDB 449 e-126 4RJK-A nrPDB 448 e-126 2EZ4-A nrPDB 447 e-126 1V5E-A nrPDB 445 e-125 2PGN-A nrPDB 443 e-124 5NPU-A nrPDB 431 e-121 5D6R-B nrPDB 429 e-120 3EYA-A nrPDB 428 e-120 2JI6-A nrPDB 403 e-112 6A50-A nrPDB 401 e-112 2VBI-A nrPDB 393 e-109 4K9Q-A nrPDB 391 e-109 4Q9D-A nrPDB 391 e-109 4QQ8-A nrPDB 388 e-108 2Q28-A nrPDB 385 e-107 5EUJ-A nrPDB 382 e-106 1OVM-A nrPDB 382 e-106 4ZP1-A nrPDB 378 e-105 4COK-A nrPDB 368 e-102 6EFG-A nrPDB 363 e-100 2VBF-A nrPDB 361 e-100 1UPC-A nrPDB 361 e-100 1QPB-A nrPDB 357 1e-98 2Q5O-A nrPDB 348 4e-96 2JLA-A nrPDB 188 9e-48 3LQ1-A nrPDB 185 7e-47 5ESS-A nrPDB 145 8e-35 Sequences not found previously or not previously below threshold: 2X7J-A nrPDB 173 3e-43 5B47-B nrPDB 56 4e-08 3I9V-3 nrPDB 46 7e-05 3CF4-G nrPDB 45 1e-04 6N2O-B nrPDB 44 3e-04 5B48-A nrPDB 42 7e-04 5W21-B nrPDB 41 0.002 4MZD-A nrPDB 41 0.002 1E1H-A nrPDB 41 0.002 3KIA-A nrPDB 41 0.002 6G72-G nrPDB 41 0.002 2DGA-A nrPDB 40 0.003 2OG2-A nrPDB 40 0.003 3PK1-A nrPDB 40 0.003 3AIW-A nrPDB 40 0.004 3KCC-A nrPDB 39 0.004 5ZVL-A nrPDB 39 0.006 5XTU-A nrPDB 39 0.008 2AKJ-A nrPDB 39 0.009 3DVA-A nrPDB 39 0.010 3LY9-A nrPDB 38 0.010 5M85-A nrPDB 38 0.011 6C7N-A nrPDB 38 0.011 4EM2-A nrPDB 38 0.011 4B8O-A nrPDB 38 0.011 5B48-B nrPDB 38 0.012 2G0Y-A nrPDB 38 0.012 5XJN-A nrPDB 38 0.012 5YPT-A nrPDB 38 0.013 5ER0-A nrPDB 38 0.014 6MRG-A nrPDB 38 0.015 3E46-A nrPDB 38 0.017 4PHT-A nrPDB 38 0.021 1YTL-A nrPDB 37 0.022 2YAD-A nrPDB 37 0.023 3QRQ-A nrPDB 37 0.023 3ZHS-A nrPDB 37 0.024 5B46-A nrPDB 37 0.028 3HMP-A nrPDB 36 0.045 2ZMD-A nrPDB 36 0.045 5GPN-Y nrPDB 36 0.061 1X7Z-A nrPDB 36 0.076 3N6R-B nrPDB 35 0.092 5YNL-A nrPDB 35 0.10 1IK6-A nrPDB 35 0.11 1UM9-A nrPDB 35 0.12 5LUC-A nrPDB 35 0.13 5T5M-B nrPDB 34 0.18 4LZZ-A nrPDB 34 0.19 1NY5-A nrPDB 34 0.19 2A1T-A nrPDB 34 0.21 4B7O-A nrPDB 34 0.21 4AIP-A nrPDB 34 0.21 4QRX-A nrPDB 34 0.24 6IBP-A nrPDB 34 0.25 6N2O-A nrPDB 34 0.25 3DC2-A nrPDB 34 0.30 1M93-B nrPDB 33 0.33 1C8O-A nrPDB 33 0.33 5CFZ-A nrPDB 33 0.36 3BC1-A nrPDB 33 0.64 5J7Z-A nrPDB 33 0.66 5IHS-A nrPDB 33 0.66 2FQ1-A nrPDB 32 0.78 5BTR-A nrPDB 32 1.0 4MB2-A nrPDB 31 1.3 1E5X-A nrPDB 31 1.5 6GCS-A nrPDB 31 1.8 1G3Q-A nrPDB 31 2.1 6GUA-A nrPDB 31 2.3 3WDK-A nrPDB 30 3.2 1RVG-A nrPDB 30 4.2 3CZB-A nrPDB 29 5.9 >1T9B-A nrPDB Length = 677 Score = 811 bits (2094), Expect = 0.0, Method: Composition-based stats. Identities = 634/664 (95%), Positives = 640/664 (96%), Gaps = 4/664 (0%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPA----PSFNVDPLEQPAEPSKLAKKLRAEP 83 R + + + R + SP + + A PSFNVDPLEQPAEPSKLAKKLRAEP Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMGSAPSFNVDPLEQPAEPSKLAKKLRAEP 73 Query: 84 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAG 143 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAG Sbjct: 74 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAG 133 Query: 144 HMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQE 203 HMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQE Sbjct: 134 HMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQE 193 Query: 204 ADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIP 263 ADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIP Sbjct: 194 ADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIP 253 Query: 264 TKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKEL 323 TKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKEL Sbjct: 254 TKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKEL 313 Query: 324 SDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTG 383 SDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTG Sbjct: 314 SDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTG 373 Query: 384 NISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKE 443 NISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKE Sbjct: 374 NISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKE 433 Query: 444 RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMW 503 RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMW Sbjct: 434 RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMW 493 Query: 504 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA 563 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA Sbjct: 494 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA 553 Query: 564 VQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQE 623 VQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQE Sbjct: 554 VQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQE 613 Query: 624 ELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRT 683 ELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRT Sbjct: 614 ELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTELRHKRT 673 Query: 684 GGKH 687 GGKH Sbjct: 674 GGKH 677 >6DEO-A nrPDB Length = 682 Score = 766 bits (1977), Expect = 0.0, Method: Composition-based stats. Identities = 460/670 (68%), Positives = 546/670 (81%), Gaps = 11/670 (1%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNV----------DPLEQPAEPSKLAK 77 R + + + R + SP + + A +FN DP + S +++ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMAFNTADTSTQPIINDPTLNKHQSSAISR 73 Query: 78 KLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPK 137 K + E MD SF+GLTGG+IF+EMM R VDTVFGY GGAILPV+DAI+NSDKF FVLP+ Sbjct: 74 K-KKEQLMDDSFIGLTGGEIFHEMMLRHKVDTVFGYAGGAILPVFDAIYNSDKFKFVLPR 132 Query: 138 HEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIG 197 HEQGAGHMAEGYARASGKPGVVLVTSGPGATNV+TPMADA DG+P+VVF+GQVPT+AIG Sbjct: 133 HEQGAGHMAEGYARASGKPGVVLVTSGPGATNVITPMADALMDGVPLVVFSGQVPTTAIG 192 Query: 198 TDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAI 257 TDAFQEAD+VGISRSCTKWNVMVK+V ELP RINEAFEIAT+GRPGPVLVDLPKDVTA+I Sbjct: 193 TDAFQEADIVGISRSCTKWNVMVKNVAELPRRINEAFEIATTGRPGPVLVDLPKDVTASI 252 Query: 258 LRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGP 317 LR IP TTLPSNAL+Q+T +A EF ++I +AA+++N AKKP++Y GAGILN+ GP Sbjct: 253 LRESIPINTTLPSNALSQITKKAVSEFTSEAIKRAANILNKAKKPIIYAGAGILNNEQGP 312 Query: 318 RLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARF 377 +LLKEL+D+A IPVTTTLQGLG+FDQ DPKSLDMLGMHG A AN A+QNAD IIA+GARF Sbjct: 313 KLLKELADKANIPVTTTLQGLGAFDQRDPKSLDMLGMHGSAAANTAIQNADCIIALGARF 372 Query: 378 DDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSK 437 DDRVTGNISKFAPEA+ AA+EGRGGI+HFE+SPKNINKVV+ A+EGD T NL + Sbjct: 373 DDRVTGNISKFAPEAKLAASEGRGGILHFEISPKNINKVVEATEAIEGDVTANLQSFIPL 432 Query: 438 IFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGV 497 + ++ R EWF +IN+WKK+YPY+Y ETPGS IKPQT+IK++S A + VIVTTGV Sbjct: 433 VDSIENRPEWFNKINEWKKKYPYSYQLETPGSLIKPQTLIKEISDQAQTYNKEVIVTTGV 492 Query: 498 GQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTL 557 GQHQMWAAQH+TW P T ITSGGLGTMGYGLPAAIGAQVAKP+++VIDIDGDASFNMTL Sbjct: 493 GQHQMWAAQHFTWTQPRTMITSGGLGTMGYGLPAAIGAQVAKPDAIVIDIDGDASFNMTL 552 Query: 558 TELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGL 617 TELSSAVQAG P+K+ +LNNEEQGMVTQWQSLFYEHRYSHTHQ NPDF+KLAE+M +KG+ Sbjct: 553 TELSSAVQAGAPIKVCVLNNEEQGMVTQWQSLFYEHRYSHTHQSNPDFMKLAESMNVKGI 612 Query: 618 RVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVERQQTE 677 R+ Q+EL + +KEF+ PVLLEV V+KKVPVLPMV G LD+FI +D EVE+QQ + Sbjct: 613 RITNQQELKSGVKEFLDATEPVLLEVIVEKKVPVLPMVPAGKALDDFILWDAEVEKQQND 672 Query: 678 LRHKRTGGKH 687 LR +RTGGK+ Sbjct: 673 LRKERTGGKY 682 >5WJ1-A nrPDB Length = 590 Score = 533 bits (1372), Expect = e-151, Method: Composition-based stats. Identities = 249/587 (42%), Positives = 347/587 (59%), Gaps = 35/587 (5%) Query: 92 LTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYAR 151 G I E + RQ V+TVF YPGGA + ++ A+ S VLP+HEQG AEGYAR Sbjct: 12 RKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYAR 71 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISR 211 +SGKPG+ + TSGPGATN+V+ +ADA D +P+V TGQVP IGTDAFQE +V ++R Sbjct: 72 SSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTR 131 Query: 212 SCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSN 271 S TK N +V VE++P I EAF +ATSGRPGPVLVD+PKD+ + LP Sbjct: 132 SITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLP-G 190 Query: 272 ALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPV 331 ++++ +D + Q + LI+ +KKPVLYVG G LN +D L + IPV Sbjct: 191 YMSRMPKPPEDSHLEQIVR----LISESKKPVLYVGGGCLNSSD---ELGRFVELTGIPV 243 Query: 332 TTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPE 391 +TL GLGS+ +D SL MLGMHG AN AV+++DL++A G RFDDRVTG + FA Sbjct: 244 ASTLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFA-- 301 Query: 392 ARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSE----- 446 R I+H ++ I K ++V GD L M + E + Sbjct: 302 -------SRAKIVHIDIDSAEIGKNKTPHVSVCGDVKLALQGMNKVLENRAEELKLDFGV 354 Query: 447 WFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQ 506 W ++N K+++P ++ +T G I PQ IK L ++ T I++TGVGQHQMWAAQ Sbjct: 355 WRNELNVQKQKFPLSF--KTFGEAIPPQYAIKVLDEL---TDGKAIISTGVGQHQMWAAQ 409 Query: 507 HWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQA 566 + ++ P +++SGGLG MG+GLPAAIGA VA P+++V+DIDGD SF M + EL++ Sbjct: 410 FYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVE 469 Query: 567 GTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLN--------PDFIKLAEAMGLKGLR 618 PVK+L+LNN+ GMV QW+ FY+ +HT + P+ + A A G+ R Sbjct: 470 NLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAAR 529 Query: 619 VKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFI 665 V K+ +L ++ + T GP LL+V + VLPM+ G ++ I Sbjct: 530 VTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVI 576 >2PAN-A nrPDB Length = 616 Score = 477 bits (1226), Expect = e-134, Method: Composition-based stats. Identities = 174/604 (28%), Positives = 284/604 (47%), Gaps = 52/604 (8%) Query: 88 SFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAE 147 S + ++ ++ + T FG PG AI P Y A+ +L +H +GA HMAE Sbjct: 23 SMAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAE 82 Query: 148 GYARAS-GKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADV 206 GY RA+ G GV L TSGP T+++T + A AD IP++ TGQ P + + + FQ D+ Sbjct: 83 GYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDI 142 Query: 207 VGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKT 266 I++ +K V V+ +P + +AF + SGRPGPVLVDLP DV A + Sbjct: 143 EAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYE 202 Query: 267 TLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDR 326 LP + I KA +++ A++PV+ G G++N AD LL++ ++ Sbjct: 203 PLPVY---------KPAASRMQIEKAVEMLIQAERPVIVAGGGVIN-ADAAALLQQFAEL 252 Query: 327 AQIPVTTTLQGLGSFDQEDPKSLDMLGMHGC-ATANLAVQNADLIIAVGARFDDRVTGNI 385 +PV TL G G + M+G+ N + +D++ +G RF +R TG++ Sbjct: 253 TSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSV 312 Query: 386 SKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNL------GKMMSKIF 439 K+ I+H ++ P I +V+ + + DA L + M K Sbjct: 313 EKY---------TEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAG 363 Query: 440 PVKERSEWFAQINKWKKE-YPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVG 498 + R EW A + K+ + + P +KPQ V ++++K GR V T +G Sbjct: 364 RLPCRKEWVADCQQRKRTLLRKTHFDNVP---VKPQRVYEEMNKA---FGRDVCYVTTIG 417 Query: 499 QHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLT 558 Q+ AAQ +I G G +G+ +PAA+G A P+ V+ I GD F + Sbjct: 418 LSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIE 477 Query: 559 ELSSAVQAGTPVKILILNNEEQGMVTQWQS----------LFYEHRYSHTHQLNPDFIKL 608 EL+ Q P +++NN G++ Q Q F S + D +K+ Sbjct: 478 ELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKV 537 Query: 609 AEAMGLKGLRVKKQEELDAKLKEF----VSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEF 664 AE +G K +RV K E++ ++ + PV++EV +++ + ++ GS LD Sbjct: 538 AEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILER----VTNISMGSELDNV 593 Query: 665 INFD 668 + F+ Sbjct: 594 MEFE 597 >5AHK-A nrPDB Length = 588 Score = 449 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 169/578 (29%), Positives = 271/578 (46%), Gaps = 31/578 (5%) Query: 96 QIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGK 155 ++++ NV F GG I + D+I+ K V HEQGA A +R + Sbjct: 25 DAVAKILADNNVLYGFELIGGMITHLVDSINLLGKTKLVSMHHEQGAAFAASAVSRVTHH 84 Query: 156 --PGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTS------AIGTDAFQEADVV 207 G+ L TSGPGATN++T +AD + D P + TGQV T I FQE D V Sbjct: 85 KTLGLALATSGPGATNLITGIADCWLDSHPCIFLTGQVNTHELKGKRDIRQQGFQELDSV 144 Query: 208 GISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTT 267 + S TK+ +KS +EL + +A +IA GRPGPVL+D+P D+ A + + Sbjct: 145 ALVTSITKYAYQIKSADELVPCLRKAIQIAKEGRPGPVLLDIPMDIQRADIDEALLNNPM 204 Query: 268 LPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRA 327 P + + + D ++ + + AKKP+L +G G +N + + L+++ R Sbjct: 205 TPEPKVQRPSIAMSD------LDFIINKLQNAKKPLLLIGGGAVNSSGFQKWLEQIELR- 257 Query: 328 QIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISK 387 IP +L+G D L MLG +G AN AVQN DL++ +G+R D R TG Sbjct: 258 GIPYVASLKGAEKIKASD-LYLGMLGAYGTRAANHAVQNCDLLLVLGSRMDVRQTGA--- 313 Query: 388 FAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEW 447 PE AE II ++ +N V + + + + + PV +W Sbjct: 314 -QPEDFARNAE----IIQIDLQEGQLNNRVIADFSYQIELSEYFSRFSPLQIPVNN--DW 366 Query: 448 FAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQH 507 K+++ +++E + P + +L+K+ I+ VG +QMWAA Sbjct: 367 SVWTALLKEKFRVTFIDEYTTWNLSPFGLFTQLNKLTERVALDYIL--DVGNNQMWAAHT 424 Query: 508 WTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAG 567 SGGLG+MG+ +PAAIGA A + +I I GD + + EL + Sbjct: 425 LRLNAQQAMHHSGGLGSMGFAIPAAIGACYAG-KKPIIVITGDGGAQLNIQELDIIARDK 483 Query: 568 TPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNP--DFIKLAEAMGLKGLRVKKQEEL 625 P+ +++NN GMV +Q +++E R S T+ F K+ EA ++ + + Sbjct: 484 LPILTIVMNNHSLGMVRGFQEMYFEGRNSSTYWNGYTSQFKKIGEAYRVESKTIISMQAF 543 Query: 626 DAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDE 663 + L+ F+ + P+LLEV + P + G +D+ Sbjct: 544 SSALESFLESPRPLLLEVSMSDARECRPRLEYGRAIDQ 581 >4RJK-A nrPDB Length = 571 Score = 448 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 160/576 (27%), Positives = 271/576 (47%), Gaps = 34/576 (5%) Query: 78 KLRAEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPK 137 K E S V G ++ + + Q V VFG PG I V+DA+ + ++ + Sbjct: 4 KATKEQ---KSLVKNRGAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKGP-EIIVAR 59 Query: 138 HEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIG 197 HEQ A MA+ R +GKPGVVLVTSGPGA+N+ T + A +G P+V G V + Sbjct: 60 HEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNLATGLLTANTEGDPVVALAGNVIRADRL 119 Query: 198 TDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAI 257 Q D + + TK++V V+ V+ +P + AF IA++G+ G V P+DV Sbjct: 120 KRTHQSLDNAALFQPITKYSVEVQDVKNIPEAVTNAFRIASAGQAGAAFVSFPQDVV--- 176 Query: 258 LRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGP 317 N + + + A +L A D I AK PV+ VG + Sbjct: 177 --NEVTNTKNVRAVAAPKLGPAADDAISAAIAK-----IQTAKLPVVLVGMKGGR-PEAI 228 Query: 318 RLLKELSDRAQIPVTTTLQGLGSFDQEDP-KSLDMLGMHGCATANLAVQNADLIIAVGAR 376 + +++L + Q+P T Q G+ ++ + +G+ +L ++ AD+++ +G Sbjct: 229 KAVRKLLKKVQLPFVETYQAAGTLSRDLEDQYFGRIGLFRNQPGDLLLEQADVVLTIG-- 286 Query: 377 FDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMS 436 + ++ P+ G IIH + +I+ Q + + GD + + + Sbjct: 287 ------YDPIEYDPKFWNI--NGDRTIIHLDEIIADIDHAYQPDLELIGDIPSTINHIEH 338 Query: 437 KIFPVKERSEWFAQINKWKKEYPY---AYMEETPGSKIKPQTVIKKLSKVANDTGRHVIV 493 V E +E +I K+Y + + + P ++K+L +D HV V Sbjct: 339 DAVKV-EFAEREQKILSDLKQYMHEGEQVPADWKSDRAHPLEIVKELRNAVDD---HVTV 394 Query: 494 TTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASF 553 T +G H +W ++++ P T + S G+ T+G LP AIGA + KP V+ + GD F Sbjct: 395 TCDIGSHAIWMSRYFRSYEPLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDGGF 454 Query: 554 NMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMG 613 + EL +AV+ P+ ++ N+ MV +Q L +R S N D +K AE+ G Sbjct: 455 LFSAMELETAVRLKAPIVHIVWNDSTYDMVA-FQQLKKYNRTSAVDFGNIDIVKYAESFG 513 Query: 614 LKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 649 GLRV+ ++L L++ ++ +GPV+++V VD Sbjct: 514 ATGLRVESPDQLADVLRQGMNAEGPVIIDVPVDYSD 549 >2EZ4-A nrPDB Length = 603 Score = 447 bits (1150), Expect = e-126, Method: Composition-based stats. Identities = 144/590 (24%), Positives = 264/590 (44%), Gaps = 31/590 (5%) Query: 87 TSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIH-NSDKFNFVLPKHEQGAGHM 145 T + G +++ VD ++G PGG+I + DA+ D+ +++ +HE+ Sbjct: 6 TKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALSAERDRIHYIQVRHEEVGAMA 65 Query: 146 AEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEAD 205 A A+ +GK GV ++GPG T+++ + DA D +P++ GQ T+ + D FQE + Sbjct: 66 AAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPVLALIGQFGTTGMNMDTFQEMN 125 Query: 206 VVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTK 265 I +NV + LP I+EA A + G +V +P D+ IP + Sbjct: 126 ENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAH-QGVAVVQIPVDLP----WQQIPAE 180 Query: 266 TTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSD 325 S N + E +Q++ + + A++P++Y G G + L++LS Sbjct: 181 DWYAS--ANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIGARKAG---KELEQLSK 235 Query: 326 RAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNI 385 +IP+ +T G P L AN A+ AD+++ VG + Sbjct: 236 TLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVLFVGNNYP------- 288 Query: 386 SKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERS 445 E +A R + ++ P + K +T IAV DA L +++++ + Sbjct: 289 ---FAEVSKAFKNTR-YFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSERESTP 344 Query: 446 EWFAQINKWKKEYPY-AYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWA 504 W A + K Y A +E+ ++ V++ ++K+A I + VG + A Sbjct: 345 WWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDA---IYSIDVGDINLNA 401 Query: 505 AQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAV 564 +H + ITS TMG G+P AI A++ PE V ++ GD +MT+ +L++ V Sbjct: 402 NRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLATQV 461 Query: 565 QAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEE 624 Q PV ++ N + G + Q ++ + + DF K+A+ + ++ RV K E+ Sbjct: 462 QYHLPVINVVFTNCQYGWIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVNKIEQ 521 Query: 625 LDAKLKE--FVSTKGPVLLEVEVDKKVPVLPMVAGGSGLDEFINFDPEVE 672 L ++ ++ PVL++ + P+ A LD ++ ++E Sbjct: 522 LPDVFEQAKAIAQHEPVLIDAVIT---GDRPLPAEKLRLDSAMSSAADIE 568 >1V5E-A nrPDB Length = 590 Score = 445 bits (1143), Expect = e-125, Method: Composition-based stats. Identities = 136/571 (23%), Positives = 252/571 (44%), Gaps = 32/571 (5%) Query: 91 GLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAI-HNSDKFNFVLPKHEQGAGHMAEGY 149 + G +++ DT++G P G + + DA+ + F+ KHE+ A Sbjct: 3 KINIGLAVMKILESWGADTIYGIPSGTLSSLMDAMGEEENNVKFLQVKHEEVGAMAAVMQ 62 Query: 150 ARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGI 209 ++ G GV + + GPGA++++ + DA D IP+V G P + DAFQE + + Sbjct: 63 SKFGGNLGVTVGSGGPGASHLINGLYDAAMDNIPVVAILGSRPQRELNMDAFQELNQNPM 122 Query: 210 SRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLP 269 +N V E+LP ++EA +A + R G ++++P D + N + Sbjct: 123 YDHIAVYNRRVAYAEQLPKLVDEAARMAIAKR-GVAVLEVPGDFAKVEIDN---DQWYSS 178 Query: 270 SNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQI 329 +N+L + A Q I+ A +L+N +K+PV+Y G G + H ++EL+ + + Sbjct: 179 ANSLRKYAPIAP---AAQDIDAAVELLNNSKRPVIYAGIGTMGHGPA---VQELARKIKA 232 Query: 330 PVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFD-DRVTGNISKF 388 PV TT + +F+ + G AN + AD ++ G+ F V G Sbjct: 233 PVITTGKNFETFEWDFEALTGSTYRVGWKPANETILEADTVLFAGSNFPFSEVEGTFRNV 292 Query: 389 APEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWF 448 I ++ P + K +A+ GDA + ++++K+ V+E + W Sbjct: 293 D------------NFIQIDIDPAMLGKRHHADVAILGDAALAIDEILNKVDAVEESAWWT 340 Query: 449 AQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHW 508 A + Y M ET + + + N I + VG + +H Sbjct: 341 ANLKNIANWREYINMLETKEEG--DLQFYQVYNAINNHADEDAIYSIDVGNSTQTSIRHL 398 Query: 509 TWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGT 568 + + TS TMG +P +GA+ P+ V +I GD +F+MT ++ + V+ Sbjct: 399 HMTPKNMWRTSPLFATMGIAIPGGLGAKNTYPDRQVWNIIGDGAFSMTYPDVVTNVRYNM 458 Query: 569 PVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAK 628 PV ++ +N E + ++ + + D+ K+AEA G KG V + E++D Sbjct: 459 PVINVVFSNTEYAFIKNKYEDTNKNLF-GVDFTDVDYAKIAEAQGAKGFTVSRIEDMDRV 517 Query: 629 LKEFVSTKG---PVLLEVEV--DKKVPVLPM 654 + E V+ V+++ ++ D+ +PV + Sbjct: 518 MAEAVAANKAGHTVVIDCKITQDRPIPVETL 548 >2PGN-A nrPDB Length = 589 Score = 443 bits (1138), Expect = e-124, Method: Composition-based stats. Identities = 137/580 (23%), Positives = 233/580 (40%), Gaps = 36/580 (6%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVL-PKHEQGAGHMAEGYAR 151 G + E + + V G+ G V DA S V+ P E G M GY Sbjct: 5 RGADLIVEALEEYGTEQVVGFIGHTSHFVADAFSKSHLGKRVINPATELGGAWMVNGYNY 64 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISR 211 + V G + M +A IP V G + Sbjct: 65 VKDRSAAVGAWHCVGNLLLHAAMQEARTGRIPAVHIGLNSDGRLAGRSEAAQQVPWQSFT 124 Query: 212 SCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSN 271 + V+ ++++ I+EAF +A GP VD+P D+TA + I K +P Sbjct: 125 PIARSTQRVERLDKVGEAIHEAFRVAEGHPAGPAYVDIPFDLTA----DQIDDKALVPRG 180 Query: 272 ALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPV 331 A + + + +AA + AK PV+ G G+ LLK L++ +PV Sbjct: 181 ATRAKSVLHAPN---EDVREAAAQLVAAKNPVILAGGGVARSGGSEALLK-LAEMVGVPV 236 Query: 332 TTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDR--VTGNISKFA 389 TT G G F + ++ G G +AN + AD ++ +G+R D G I+K Sbjct: 237 VTTSTGAGVFPETHALAMGSAGFCGWKSANDMMAAADFVLVLGSRLSDWGIAQGYITKMP 296 Query: 390 PEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMS--------KIFPV 441 +H + P + ++V DA T + +++ K Sbjct: 297 ------------KFVHVDTDPAVLGTFYFPLLSVVADAKTFMEQLIEVLPGTSGFKAVRY 344 Query: 442 KERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQ 501 +ER E F Q +++ + E+ G + P ++ + +++V I+ T +G H Sbjct: 345 QER-ENFRQATEFRAAWDGWVREQESGDGM-PASMFRAMAEVRKVQRPEDIIVTDIGNHT 402 Query: 502 MWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELS 561 + + P +TS G +G G P A+GAQ+A+P S V GD + E Sbjct: 403 LPMFGGAILQRPRRLVTSMAEGILGCGFPMALGAQLAEPNSRVFLGTGDGALYYHFNEFR 462 Query: 562 SAVQAGTPVKILILNNEEQGMVTQWQSLFYE-HRYSHTHQLNPDFIKLAEAMGLKGLRVK 620 AV+ PV ++ NE G W + ++ + + T +NPD++ +A+A G G V+ Sbjct: 463 VAVEHKLPVITMVFTNESYG--ANWTLMNHQFGQNNWTEFMNPDWVGIAKAFGAYGESVR 520 Query: 621 KQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGSG 660 + ++ L+ + + P L+E+ V K + GG G Sbjct: 521 ETGDIAGALQRAIDSGKPALIEIPVSKTQGLASDPVGGVG 560 >5NPU-A nrPDB Length = 563 Score = 431 bits (1107), Expect = e-121, Method: Composition-based stats. Identities = 124/593 (20%), Positives = 219/593 (36%), Gaps = 68/593 (11%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G +++ + F G L + D + + V +E G AEGYARA Sbjct: 4 TVGHYLATRLAQIGLKHHFAVAGDYNLVLLDQLLKNKDLEQVYCCNELNCGFSAEGYARA 63 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEAD------- 205 +G G +VT GA + + A+A+ +P+++ +G T+ G+ Sbjct: 64 NG-VGAAVVTFSVGALSAFNAIGGAYAENLPVILISGAPNTNDHGSGHILHHTIGTTDYG 122 Query: 206 -VVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 + +++ T V + E+ P I+ A A + P +++ +V A P P Sbjct: 123 YQLEMAKQITCAAVSITHAEDAPALIDHAIRTALREKK-PAYIEIACNVAAQPCARPGPV 181 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 L + +E + ++ A D I +KPVL VG G L A + EL+ Sbjct: 182 SALLNE-------PTSDEETLKAAVEAALDFIEKREKPVLLVG-GKLRAAGAEEAVVELA 233 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLD-MLGMHGCATANLAVQNADLIIAVGARFDDRVTG 383 D V T F ++ P + G V AD II +G F+D T Sbjct: 234 DALGCAVATMAAAKSFFPEDHPGYVGTYWGEVSSPGVEEIVDWADGIICLGPVFNDYSTV 293 Query: 384 NISKFA---------PEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKM 434 + + P E G IH + + + V + A +GK Sbjct: 294 GWTAWPKGENVVLVDPHHITVGGEEFTG-IHLKDFLTALTERVPKKDATLDQFKARVGKP 352 Query: 435 MSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVT 494 ++ P + P + + + +++ + N +I Sbjct: 353 AAEKVPAAD-----------------------PNAPLTRAELCRQIQGLLNPN-TTLIAE 388 Query: 495 TGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFN 554 TG + A + G +G+ +PA G VA+PE + + GD SF Sbjct: 389 TG---DSWFNAMRMKLPHGARVELEMQWGHIGWSVPATFGYAVAEPERRNVLMVGDGSFQ 445 Query: 555 MTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGL 614 +T E++ V+ P+ I ++NN + H + + N D+ L E Sbjct: 446 LTAQEVAQMVRRKLPIIIFLINNRGYTI------EVKIHDGPYNNIKNWDYAGLMEVFNA 499 Query: 615 K-----GLRVKKQEELDAKLKEFVSTK-GPVLLEVEVDKKVPVLPMVAGGSGL 661 + GL+ EL +K+ ++ + GP L+E +D+ +V G + Sbjct: 500 EDGKGLGLKATTGGELAEAIKKALAHREGPTLIECVIDRDDCTPELVTWGKKV 552 >5D6R-B nrPDB Length = 579 Score = 429 bits (1103), Expect = e-120, Method: Composition-based stats. Identities = 154/565 (27%), Positives = 253/565 (44%), Gaps = 31/565 (5%) Query: 94 GGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARAS 153 G + + Q V VFG PG I V+D++ +S + +HE A MA R + Sbjct: 33 GADLVVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSS-IRIIPVRHEANAAFMAAAVGRIT 91 Query: 154 GKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSC 213 GK GV LVTSGPG +N++T MA A ++G P+V G V + Q D V + Sbjct: 92 GKAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKQVHQSMDTVAMFSPV 151 Query: 214 TKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNAL 273 TK+ + V + + L ++ AF A GRPG V LP+DV + + LP++ Sbjct: 152 TKYAIEVTAPDALAEVVSNAFRAAEQGRPGSAFVSLPQDVVDGPV-----SGKVLPASGA 206 Query: 274 NQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTT 333 Q+ + D +I++ A LI AK P+ +G + + + + L+ L + + IPVT+ Sbjct: 207 PQMGAAPDD-----AIDQVAKLIAQAKNPIFLLGL-MASQPENSKALRRLLETSHIPVTS 260 Query: 334 TLQGLGSFDQED-PKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEA 392 T Q G+ +Q++ + +G+ + +Q ADL+I +G + ++ P Sbjct: 261 TYQAAGAVNQDNFSRFAGRVGLFNNQAGDRLLQLADLVICIG--------YSPVEYEPAM 312 Query: 393 RRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQI- 451 G ++H +V P + + + GD L K+ I S A+I Sbjct: 313 WN---SGNATLVHIDVLPAYEERNYTPDVELVGDIAGTLNKLAQNIDHRLVLSPQAAEIL 369 Query: 452 --NKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWT 509 + ++E + + P +++ + + N V +T +G +W A++ Sbjct: 370 RDRQHQRELLDRRGAQLNQFALHPLRIVRAMQDIVNSD---VTLTVDMGSFHIWIARYLY 426 Query: 510 WRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTP 569 + S G TMG LP AIGA + PE V+ + GD F + EL +AV+ Sbjct: 427 SFRARQVMISNGQQTMGVALPWAIGAWLVNPERKVVSVSGDGGFLQSSMELETAVRLKAN 486 Query: 570 VKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKL 629 V LI + MV + Y+ R S DF AE+ G KG V+ E L+ L Sbjct: 487 VLHLIWVDNGYNMVAIQEEKKYQ-RLSGVEFGPMDFKAYAESFGAKGFAVESAEALEPTL 545 Query: 630 KEFVSTKGPVLLEVEVDKKVPVLPM 654 + + GP ++ + VD + L M Sbjct: 546 RAAMDVDGPAVVAIPVDYRDNPLLM 570 >3EYA-A nrPDB Length = 549 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 145/570 (25%), Positives = 259/570 (45%), Gaps = 41/570 (7%) Query: 90 VGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGY 149 + T + + V ++G G ++ + D+++ ++ +HE+ A A Sbjct: 1 MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAE 60 Query: 150 ARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGI 209 A+ SG+ V + GPG +++ + D + +P++ +P+S IG+ FQE + Sbjct: 61 AQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQEL 120 Query: 210 SRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLP 269 R C+ + +V S E++P + A A R G +V LP DV P P T+ Sbjct: 121 FRECSHYCELVSSPEQIPQVLAIAMRKAVLNR-GVSVVVLPGDVAL----KPAPEGATMH 175 Query: 270 SNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQI 329 Q ++E + K A L+ + L G+G A + L E + + + Sbjct: 176 WYHAPQPVVTPEEE----ELRKLAQLLRYSSNIALMCGSGC---AGAHKELVEFAGKIKA 228 Query: 330 PVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFA 389 P+ L+G + ++P + M G+ G ++ + NAD ++ +G +F R F Sbjct: 229 PIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRA------FY 282 Query: 390 PEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFA 449 P + II +++P +I + +A+ GD + L ++ P+ E Sbjct: 283 PTDAK--------IIQIDINPASIGAHSKVDMALVGDIKSTLRALL----PLVEEKADRK 330 Query: 450 QINKWKKEYPYAY-----MEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWA 504 ++K ++Y A + + I PQ + +++S A D I T VG +WA Sbjct: 331 FLDKALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDA---IFTCDVGTPTVWA 387 Query: 505 AQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAV 564 A++ + S G+M +P A+GAQ +PE V+ + GD F+M + + S V Sbjct: 388 ARYLKMNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVV 447 Query: 565 QAGTPVKILILNNEEQGMVT-QWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQE 623 Q PVKI++ NN G V + ++ Y + H N F ++AEA G+ G+RV+K Sbjct: 448 QMKLPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTN--FARIAEACGITGIRVEKAS 505 Query: 624 ELDAKLKEFVSTKGPVLLEVEVDKKVPVLP 653 E+D L+ S GPVL++V V K+ +P Sbjct: 506 EVDEALQRAFSIDGPVLVDVVVAKEELAIP 535 >2JI6-A nrPDB Length = 568 Score = 403 bits (1035), Expect = e-112, Method: Composition-based stats. Identities = 135/578 (23%), Positives = 230/578 (39%), Gaps = 37/578 (6%) Query: 86 DTSFVGLTGG-QIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGH 144 + V LT G + + + ++DT++G G I + + D F +HEQ AG+ Sbjct: 3 NDDNVELTDGFHVLIDALKMNDIDTMYGVVGIPITNLAR-MWQDDGQRFYSFRHEQHAGY 61 Query: 145 MAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTS--AIGTDAFQ 202 A GKPGV L S PG N VT +A A + PM++ +G + ++ Sbjct: 62 AASIAGYIEGKPGVCLTVSAPGFLNGVTSLAHATTNCFPMILLSGSSEREIVDLQQGDYE 121 Query: 203 EADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPI 262 E D + ++R K + + S++++P+ I A A SGRPG V VDLP + + Sbjct: 122 EMDQMNVARPHCKASFRINSIKDIPIGIARAVRTAVSGRPGGVYVDLPAKLFGQTISVEE 181 Query: 263 PTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKE 322 K A+D +I +AADLI AK+PV+ +G G +A ++ Sbjct: 182 ANKLLFKPIDPAPAQIPAED-----AIARAADLIKNAKRPVIMLGKGAA-YAQCDDEIRA 235 Query: 323 LSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVT 382 L + IP G P+S AT A+ D+ + +GAR + + Sbjct: 236 LVEETGIPFLPMGMAKGLLPDNHPQSA-------AATRAFALAQCDVCVLIGARLNWLMQ 288 Query: 383 GNISK-FAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIF-P 440 K + E ++ + ++ ++ V GD + + + + Sbjct: 289 HGKGKTWGDELKKY--------VQIDIQANEMDSNQPIAAPVVGDIKSAVSLLRKALKGA 340 Query: 441 VKERSEWF----AQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTG 496 K +EW A+++ K + ETP + + + I Sbjct: 341 PKADAEWTGALKAKVDGNKAKLAGKMTAETPSGMMNYSNSLGVVRDFM--LANPDISLVN 398 Query: 497 VGQHQMWAAQHW-TWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNM 555 G + + + P + SG G MG G+ + A VI ++GD++F Sbjct: 399 EGANALDNTRMIVDMLKPRKRLDSGTWGVMGIGMGYCVAAAAVT-GKPVIAVEGDSAFGF 457 Query: 556 TLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLK 615 + EL + + PV ++I+NN G+ ++ S T + + EA G K Sbjct: 458 SGMELETICRYNLPVTVIIMNNG--GIYKGNEADPQPGVISCTRLTRGRYDMMMEAFGGK 515 Query: 616 GLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLP 653 G EL A L+E V++ P L+ +D V Sbjct: 516 GYVANTPAELKAALEEAVASGKPCLINAMIDPDAGVES 553 >6A50-A nrPDB Length = 549 Score = 401 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 140/548 (25%), Positives = 233/548 (42%), Gaps = 36/548 (6%) Query: 98 FNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPG 157 E++ RQ +DTVFG PG LP + F ++L E +A+GYA+AS KP Sbjct: 29 TYELLRRQGIDTVFGNPGSNELPFLKDF--PEDFRYILALQEACVVGIADGYAQASRKPA 86 Query: 158 VVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQ-EADVVGISRSCTKW 216 + + S G N + +++A P++V GQ + IG +A + D + R KW Sbjct: 87 FINLHSAAGTGNAMGALSNARTSHSPLIVTAGQQTRAMIGVEAGETNVDAANLPRPLVKW 146 Query: 217 NVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQL 276 + S E+P ++ A +A+ GPV + +P D P L ++ Sbjct: 147 SYEPASAAEVPHAMSRAIHMASMAPQGPVYLSVPYDDWDKDAD---PQSHHLFDRHVSS- 202 Query: 277 TSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQ 336 + R D Q ++ +N A P + +G + + A+ L++R + PV Sbjct: 203 SVRLND----QDLDILVKALNSASNPAIVLGPDV-DAANANADCVMLAERLKAPVWVAPS 257 Query: 337 G-LGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRA 395 F P L G A + ++ D+++ +GA V + ++ R Sbjct: 258 APRCPFPTRHPCFRG-LMPAGIAAISQLLEGHDVVLVIGAPVFRYVFYDPGQYLKPGTR- 315 Query: 396 AAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWK 455 +I P + A+ D G M S + + E S + Sbjct: 316 -------LISVTCDPLEAARA-PMGDAIVADI----GAMASALANLVEESS-----RQLP 358 Query: 456 KEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHT 515 P + ++ P+TV L+ +A + ++ +T QMW Q RNP + Sbjct: 359 TAAPEPAKVDQDAGRLHPETVFDTLNDMAPENAIYLNESTST-TAQMW--QRLNMRNPGS 415 Query: 516 FITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILIL 575 + G +G+ LPAAIG Q+A+PE VI + GD S N +++ L +A Q P +I+ Sbjct: 416 YYFCAA-GGLGFALPAAIGVQLAEPERQVIAVIGDGSANYSISALWTAAQYNIPTIFVIM 474 Query: 576 NNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVST 635 NN GM+ + + DF LA+ G++ L+ E+L L+E +S Sbjct: 475 NNGTYGMLRWFAGVLEAENVPGLDVPGIDFRALAKGYGVQALKADNLEQLKGSLQEALSA 534 Query: 636 KGPVLLEV 643 KGPVL+EV Sbjct: 535 KGPVLIEV 542 >2VBI-A nrPDB Length = 566 Score = 393 bits (1008), Expect = e-109, Method: Composition-based stats. Identities = 104/584 (17%), Positives = 213/584 (36%), Gaps = 55/584 (9%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G E + + + F G L + D + + + +E G AEGYAR+ Sbjct: 4 TVGMYLAERLVQIGLKHHFAVAGDYNLVLLDQLLLNKDMKQIYCCNELNCGFSAEGYARS 63 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEAD------- 205 +G V VT GA + + + A+A+ +P+++ +G ++ GT Sbjct: 64 NGAAAAV-VTFSVGAISAMNALGGAYAENLPVILISGAPNSNDQGTGHILHHTIGKTDYS 122 Query: 206 -VVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 + ++R T + P +I+ A R P +D+ ++ + P P Sbjct: 123 YQLEMARQVTCAAESITDAHSAPAKIDHVIRTALRERK-PAYLDIACNIASEPCVRPGPV 181 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 + L ++ + + +++ L+ + PV+ +G+ L A+ + L+ Sbjct: 182 SSLLSEPEIDHTS-------LKAAVDATVALLEKSASPVMLLGSK-LRAANALAATETLA 233 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLD-MLGMHGCATANLAVQNADLIIAVGARFDDRVTG 383 D+ Q VT G F ++ G V+ +D ++ + F+D T Sbjct: 234 DKLQCAVTIMAAAKGFFPEDHAGFRGLYWGEVSNPGVQELVETSDALLCIAPVFNDYSTV 293 Query: 384 NISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKE 443 S + AE + A +G + +++ P + Sbjct: 294 GWSAWPKGPNVILAEPDRVTVD--------------GRAYDGFTLRAFLQALAEKAPARP 339 Query: 444 RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMW 503 S + + + + + + +++ ++ + V T + Sbjct: 340 ASAQKSSVPT------CSLTATSDEAGLTNDEIVRHINALLTSNTTLVAETGD----SWF 389 Query: 504 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA 563 A T G +G+ +P+A G + + + + GD SF +T E++ Sbjct: 390 NAMRMTLPRGARVELEMQWGHIGWSVPSAFGNAMGSQDRQHVVMVGDGSFQLTAQEVAQM 449 Query: 564 VQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLK-----GLR 618 V+ PV I ++NN +G V + H + + N D+ L E GL+ Sbjct: 450 VRYELPVIIFLINN--RGYVIEIAI----HDGPYNYIKNWDYAGLMEVFNAGEGHGLGLK 503 Query: 619 VKKQEELDAKLKEF-VSTKGPVLLEVEVDKKVPVLPMVAGGSGL 661 +EL + +T+GP L+E ++D+ +V G + Sbjct: 504 ATTPKELTEAIARAKANTRGPTLIECQIDRTDCTDMLVQWGRKV 547 >4K9Q-A nrPDB Length = 539 Score = 391 bits (1004), Expect = e-109, Method: Composition-based stats. Identities = 115/564 (20%), Positives = 217/564 (38%), Gaps = 43/564 (7%) Query: 92 LTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYAR 151 T +I +++ + V TV G PG FN+VL E +A+G ++ Sbjct: 2 RTVKEITFDLLRKLQVTTVVGNPGSTEETFLKDF--PSDFNYVLALQEASVVAIADGLSQ 59 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAF-QEADVVGIS 210 + KP +V + +G G N + + A+ + P+++ GQ + + + + + Sbjct: 60 SLRKPVIVNIHTGAGLGNAMGCLLTAYQNKTPLIITAGQQTREMLLNEPLLTNIEAINMP 119 Query: 211 RSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPS 270 + KW+ E++P A+ A GPV + LP D ++ +T Sbjct: 120 KPWVKWSYEPARPEDVPGAFMRAYATAMQQPQGPVFLSLPLDDWEKLIPEVDVARTVS-- 177 Query: 271 NALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIP 330 T + D + + A I +K P+L G+ I + ++R P Sbjct: 178 ------TRQGPDP---DKVKEFAQRITASKNPLLIYGSDIAR-SQAWSDGIAFAERLNAP 227 Query: 331 VTTTLQG-LGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFA 389 V F ++ P L G + +Q DLI+ +GA +F Sbjct: 228 VWAAPFAERTPFPEDHPLFQGAL-TSGIGSLEKQIQGHDLIVVIGAPVFRYYPWIAGQFI 286 Query: 390 PEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFA 449 PE ++ P +K V ++ D+ L + + I ++ Sbjct: 287 PEGST--------LLQVSDDPNMTSKAV-VGDSLVSDSKLFLIEALKLIDQREK------ 331 Query: 450 QINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWT 509 N + P + T ++P V++ L + ++ + +++ + Sbjct: 332 --NNTPQRSPMTKEDRT-AMPLRPHAVLEVLKE---NSPKEIVLVEECPSIVPLMQDVFR 385 Query: 510 WRNPHTFITSGGLGTMGYGLPAAIGAQVAK----PESLVIDIDGDASFNMTLTELSSAVQ 565 P TF T G +G+ LPAA+G + + V+ + GD SF ++ + + VQ Sbjct: 386 INQPDTFYT-FASGGLGWDLPAAVGLALGEEVSGRNRPVVTLMGDGSFQYSVQGIYTGVQ 444 Query: 566 AGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEEL 625 T V ++ NEE G++ Q+ L D + +A G K L+V+ +EL Sbjct: 445 QKTHVIYVVFQNEEYGILKQFAELEQTPNVPGLDLPGLDIVAQGKAYGAKSLKVETLDEL 504 Query: 626 DAKLKEFVSTKGPVLLEVEVDKKV 649 E +S KG ++ V + K++ Sbjct: 505 KTAYLEALSFKGTSVIVVPITKEL 528 >4Q9D-A nrPDB Length = 545 Score = 391 bits (1003), Expect = e-109, Method: Composition-based stats. Identities = 123/566 (21%), Positives = 223/566 (39%), Gaps = 41/566 (7%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T + +++ + + TVFG PG + F +VL E A MA+G+A+A Sbjct: 6 TVHDVTYDLLRKLGLTTVFGNPGSTEESFLRDF--PEDFTYVLSLQEASALAMADGFAQA 63 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAF-QEADVVGISR 211 +GKP +V + + G N + + A+ P+++ GQ D + D + + Sbjct: 64 TGKPALVNLHTAAGTGNAMGSLVAAYRANTPLIITAGQQTREMSVVDPYLNNPDATTMPK 123 Query: 212 SCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSN 271 KW+ E++P +A+ +A GPV + +P D K L Sbjct: 124 PWVKWSYEPARAEDVPAAFMQAYAVAMQPPMGPVFLSIPLDDW---------DKPALGPA 174 Query: 272 ALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPV 331 A+ +++R + + + + A+ IN AK P+L +G + A E +++ PV Sbjct: 175 AVRSVSTRVAPD--AERLAQFAERINAAKHPMLVLGPEVDR-AGAWDAGIEFAEKLGAPV 231 Query: 332 -TTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAP 390 + L SF ++ P L M A AV DL++ VGA ++ P Sbjct: 232 HASALPDRMSFPEDHPLYAGPLPMT-IAGVEQAVSAYDLVVVVGAEVFRYYPYVPGEYLP 290 Query: 391 EARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQ 450 E ++ P + V ++ GD L ++ I +R Sbjct: 291 EGTD--------LLQITADPHR-SAVAPVGDSLVGDVGIALSRLTELIDTPDDRVPPKPL 341 Query: 451 INKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTW 510 + + + P + V + LS V D V+ +T + Sbjct: 342 VRQRHSDIPSTA-------PMTSNAVYEVLSNVKPDDAAVVMESTST---MLDLFTWLPT 391 Query: 511 RNPHTFITSGGLGTMGYGLPAAIGAQVAKP----ESLVIDIDGDASFNMTLTELSSAVQA 566 +P +F +G G +G+G+PAA+G + + V+ GD SF ++ + +A Q Sbjct: 392 THPASFFATGS-GGIGWGVPAAVGIALGDRARGVDRTVVATIGDGSFQYSIQAIWTAAQH 450 Query: 567 GTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELD 626 P+ ++L N E ++ + L D +A G + V+ + L+ Sbjct: 451 KLPIVFVVLRNGEYAILKSFADLEKTPNVPGLQLPGLDISSIAAGFGCRTATVESTDMLE 510 Query: 627 AKLKEFVSTKGPVLLEVEVDKKVPVL 652 A+LK + GP +L V ++P L Sbjct: 511 AELKTALQADGPTVLVVPTLPQLPQL 536 >4QQ8-A nrPDB Length = 583 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 144/576 (25%), Positives = 245/576 (42%), Gaps = 30/576 (5%) Query: 92 LTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYAR 151 +TGG++ + + V+ +FG G I ++ A + D + +HE AGH AEGYAR Sbjct: 4 ITGGELVVRTLIKAGVEHLFGLHGIHIDTIFQACLDHD-VPIIDTRHEAAAGHAAEGYAR 62 Query: 152 ASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEA-DVVGIS 210 A K GV LVT+G G TN VTP+A+A D P++ TG T+ Q D V ++ Sbjct: 63 AGAKLGVALVTAGGGFTNAVTPIANARTDRTPVLFLTGSGALRDDETNTLQAGIDQVAMA 122 Query: 211 RSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPS 270 TKW V + E +P + +A A S GPVL+DLP D+ L N I + + Sbjct: 123 APITKWAHRVMATEHIPRLVMQAIRAALSAPRGPVLLDLPWDI----LMNQIDEDSVIIP 178 Query: 271 NALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIP 330 + + D +++A L+ A++PV+ +G+ A L +P Sbjct: 179 DLVLSAHGAHPDP---ADLDQALALLRKAERPVIVLGSEASRTARKTA-LSAFVAATGVP 234 Query: 331 VTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAP 390 V +GL P ++ + + A DL++ +GARF + P Sbjct: 235 VFADYEGLSML-SGLPDAMRGGLVQNLYSFAKADAAPDLVLMLGARFGLNTGHGSGQLIP 293 Query: 391 EARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTN---LGKMMSKIFPVKERSEW 447 + + +I + + ++ + + D L + ++ +R +W Sbjct: 294 HSAQ--------VIQVDPDACELGRLQGIALGIVADVGGTIEALAQATAQDAAWPDRGDW 345 Query: 448 FAQINKWKKE-YPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQ 506 A++ +E Y + + + P + ++K V V G +W ++ Sbjct: 346 CAKVTDLAQERYASIAAKSSSEHALHPFHASQVIAKHV---DAGVTVVADGGLTYLWLSE 402 Query: 507 HWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPE--SLVIDIDGDASFNMTLTELSSAV 564 + P F+ G L +MG G A+GAQVA E I + GD S ++ E + V Sbjct: 403 VMSRVKPGGFLCHGYLNSMGVGFGTALGAQVADLEAGRRTILVTGDGSVGYSIGEFDTLV 462 Query: 565 QAGTPVKILILNNEEQGMVTQWQSLFY-EHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQE 623 + P+ ++I+NN+ G +Q L +R + T N + +A A G G V E Sbjct: 463 RKQLPLIVIIMNNQSWGWTLHFQQLAVGPNRVTGTRLENGSYHGVAAAFGADGYHVDSVE 522 Query: 624 ELDAKLKEFVSTKGPVLLEVEVD-KKVPVLPMVAGG 658 A L + ++ P + V V +P ++ G Sbjct: 523 SFSAALAQALAHNRPACINVAVALDPIPPEELILIG 558 >2Q28-A nrPDB Length = 564 Score = 385 bits (989), Expect = e-107, Method: Composition-based stats. Identities = 131/576 (22%), Positives = 234/576 (40%), Gaps = 33/576 (5%) Query: 85 MDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIH--NSDKFNFVLPKHEQGA 142 M G I E + + N+DT++G G +PV D ++ ++ +HEQ A Sbjct: 1 MSDQLQMTDGMHIIVEALKQNNIDTIYGVVG---IPVTDMARHAQAEGIRYIGFRHEQSA 57 Query: 143 GHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTS--AIGTDA 200 G+ A + KPG+ L S PG N +T +A+A +G PM++ +G + + Sbjct: 58 GYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMISGSSDRAIVDLQQGD 117 Query: 201 FQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRN 260 ++E D + ++ K V ++L + + A ++ SGRPG V +DLP +V AA + Sbjct: 118 YEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPGGVYLDLPANVLAATMEK 177 Query: 261 PIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLL 320 T + + +S+ A L+ A++P++ +G G ++ L Sbjct: 178 DEALTTIVKVENPSPALLPCP-----KSVTSAISLLAKAERPLIILGKGAA-YSQADEQL 231 Query: 321 KELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDR 380 +E + AQIP G + P S A + A+ NAD+++ VGAR + Sbjct: 232 REFIESAQIPFLPMSMAKGILEDTHPLSA-------AAARSFALANADVVMLVGARLNWL 284 Query: 381 VTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFP 440 + +A I ++ P+ I+ + V GD +++ M++++ Sbjct: 285 LAHGKKGWA---------ADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELKQ 335 Query: 441 VKERSEW-FAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGR-HVIVTTGVG 498 + + I K+ M E + +P LS V + I G Sbjct: 336 NTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLVNEG 395 Query: 499 QHQMWAAQH-WTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTL 557 + + A++ P + G G MG G+ AIGA V S V+ I+GD++F + Sbjct: 396 ANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTS-GSPVVAIEGDSAFGFSG 454 Query: 558 TELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGL 617 E+ + + PV I+I NN + + KL +A G Sbjct: 455 MEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDAFRGVGY 514 Query: 618 RVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLP 653 V +EL L + ++ P ++ V +D Sbjct: 515 NVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTES 550 >5EUJ-A nrPDB Length = 573 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 114/582 (19%), Positives = 220/582 (37%), Gaps = 55/582 (9%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G E +++ + F G L + D + + V +E G AEGYARA Sbjct: 3 TVGMYLAERLAQIGLKHHFAVAGDYNLVLLDQLLLNKDMEQVYCCNELNCGFSAEGYARA 62 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEAD------- 205 G + VT GA + + + A+A+ +P+++ +G T+ GT Sbjct: 63 RGAAAAI-VTFSVGAISAMNAIGGAYAENLPVILISGSPNTNDYGTGHILHHTIGTTDYN 121 Query: 206 -VVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 + + + T + S EE P +I+ A R P +++ +V A P P Sbjct: 122 YQLEMVKHVTCAAESIVSAEEAPAKIDHVIRTALRERK-PAYLEIACNVAGAECVRPGPI 180 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 + L ++Q + V +++ A + + + V+ VG+ L A + L+ Sbjct: 181 NSLLRELEVDQTS-------VTAAVDAAVEWLQDRQNVVMLVGSK-LRAAAAEKQAVALA 232 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLD-MLGMHGCATANLAVQNADLIIAVGARFDDRVTG 383 DR VT G F ++ P G A V+NAD I+ + F+D T Sbjct: 233 DRLGCAVTIMAAAKGFFPEDHPNFRGLYWGEVSSEGAQELVENADAILCLAPVFNDYATV 292 Query: 384 NISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKE 443 + + +G ++ + ++V + EG + + ++ E Sbjct: 293 GWNSWP--------KGDNVMV------MDTDRVTFAGQSFEGLSLSTFAAALA------E 332 Query: 444 RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMW 503 ++ + + P + + + +++ + +T G + Sbjct: 333 KAPSRPATTQGTQAPVLGIEAAEPNAPLTNDEMTRQIQSLITSD---TTLTAETGDS-WF 388 Query: 504 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA 563 A G +G+ +P+A G V PE I + GD SF +T E++ Sbjct: 389 NASRMPIPGGARVELEMQWGHIGWSVPSAFGNAVGSPERRHIMMVGDGSFQLTAQEVAQM 448 Query: 564 VQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAM-----GLKGLR 618 ++ PV I ++NN +G V + H + + N ++ L + GL+ Sbjct: 449 IRYEIPVIIFLINN--RGYVIEIAI----HDGPYNYIKNWNYAGLIDVFNDEDGHGLGLK 502 Query: 619 VKKQEELDAKLKEFVST-KGPVLLEVEVDKKVPVLPMVAGGS 659 EL+ +K+ + +GP L+E + + ++A G Sbjct: 503 ASTGAELEGAIKKALDNRRGPTLIECNIAQDDCTETLIAWGK 544 >1OVM-A nrPDB Length = 552 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 129/573 (22%), Positives = 212/573 (36%), Gaps = 62/573 (10%) Query: 94 GGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARAS 153 + ++ D +FG PG L D + +S +V +E A + A+GYAR Sbjct: 7 VADYLLDRLTDCGADHLFGVPGDYNLQFLDHVIDSPDICWVGCANELNASYAADGYARCK 66 Query: 154 GKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADV-VGISRS 212 G +L T G G + + +A ++A+ +P++ G T+A + G R Sbjct: 67 GF-AALLTTFGVGELSAMNGIAGSYAEHVPVLHIVGAPGTAAQQRGELLHHTLGDGEFRH 125 Query: 213 CTKWNVMVKSVEELPLRINEAFEI-----ATSGRPGPVLVDLPKDVTAAILRNPIPTKTT 267 + + + + N +EI P + LP DV T Sbjct: 126 FYHMSEPITVAQAVLTEQNACYEIDRVLTTMLRERRPGYLMLPADVAKK--------AAT 177 Query: 268 LPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRA 327 P NAL + A + + A + + ++K+ L +L H L K + + Sbjct: 178 PPVNALTHKQAHADSACLKAFRDAAENKLAMSKRTALLADFLVLRHGLKHALQKWVKE-- 235 Query: 328 QIPVT--TTLQGLGSFDQEDPKSLDML-GMHGCATANLAVQNADLIIAVGARFDDRVTGN 384 +P+ T L G G FD+ G A++ AD ++ VG RF D +T Sbjct: 236 -VPMAHATMLMGKGIFDERQAGFYGTYSGSASTGAVKEAIEGADTVLCVGTRFTDTLTAG 294 Query: 385 ISKFAPEARRAAAEG---RGGIIHFEVSPKNINKVVQTQIAVE-GDATTNLGKMMSKIFP 440 + A+ + R G + F P +N+ ++T + + L S P Sbjct: 295 FTHQLTPAQTIEVQPHAARVGDVWFTGIP--MNQAIETLVELCKQHVHAGLMSSSSGAIP 352 Query: 441 VKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQH 500 + Q N W+ QT I+ + D G Sbjct: 353 FPQPDGSLTQENFWRTL----------------QTFIRPGDIILADQG-----------T 385 Query: 501 QMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTEL 560 + A FI G++GY L AA GAQ A P VI + GD + +T+ EL Sbjct: 386 SAFGAIDLRLPADVNFIVQPLWGSIGYTLAAAFGAQTACPNRRVIVLTGDGAAQLTIQEL 445 Query: 561 SSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLK----G 616 S ++ IL+LNNE G + E RY+ N + +A+ L Sbjct: 446 GSMLRDKQHPIILVLNNE--GYTVERAIHGAEQRYNDIALWNW--THIPQALSLDPQSEC 501 Query: 617 LRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 649 RV + E+L L++ + L+EV + K Sbjct: 502 WRVSEAEQLADVLEKVAHHERLSLIEVMLPKAD 534 >4ZP1-A nrPDB Length = 568 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 115/586 (19%), Positives = 214/586 (36%), Gaps = 55/586 (9%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G E + + + F G L + D + + V +E G AEGYARA Sbjct: 4 TVGTYLAERLVQIGLKHHFAVAGDYNLVLLDNLLLNKNMEQVYCCNELNCGFSAEGYARA 63 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEAD------- 205 G V VT GA + + A+A+ +P+++ +G + Sbjct: 64 KGAAAAV-VTYSVGALSAFDAIGGAYAENLPVILISGAPNNNDHAAGHVLHHALGKTDYH 122 Query: 206 -VVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 + ++++ T + + EE P +I+ + A + PV +++ ++ + P P Sbjct: 123 YQLEMAKNITAAAEAIYTPEEAPAKIDHVIKTALREKK-PVYLEIACNIASMPCAAPGPA 181 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 A + + + ++ + I K + VG+ L A + + Sbjct: 182 SALFNDEA-------SDEASLNAAVEETLKFIANRDKVAVLVGSK-LRAAGAEEAAVKFA 233 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLD-MLGMHGCATANLAVQNADLIIAVGARFDDRVTG 383 D V T F +E+P + G ++ AD +IA+ F+D T Sbjct: 234 DALGGAVATMAAAKSFFPEENPHYIGTSWGEVSYPGVEKTMKEADAVIALAPVFNDYSTT 293 Query: 384 NISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKE 443 + + AE R ++ N + + ++ L ++ K+ Sbjct: 294 GWTDIPDPKKLVLAEPRSVVV---------NGIRFPSVHLKD----YLTRLAQKVSKKTG 340 Query: 444 RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMW 503 ++F +N + + P + + + +++ + VI TG + Sbjct: 341 ALDFFKSLNAGELK---KAAPADPSAPLVNAEIARQVEALL-TPNTTVIAETG---DSWF 393 Query: 504 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA 563 AQ N G +G+ +PAA G V PE I + GD SF +T E++ Sbjct: 394 NAQRMKLPNGARVEYEMQWGHIGWSVPAAFGYAVGAPERRNILMVGDGSFQLTAQEVAQM 453 Query: 564 VQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMG---------L 614 V+ PV I ++NN + H + + N D+ L E Sbjct: 454 VRLKLPVIIFLINNYGYTIAV------MIHDGPYNNIKNWDYAGLMEVFNGNGGYDSGAG 507 Query: 615 KGLRVKKQEELDAKLKEFVS-TKGPVLLEVEVDKKVPVLPMVAGGS 659 KGL+ K EL +K ++ T GP L+E + ++ +V G Sbjct: 508 KGLKAKTGGELAEAIKVALANTDGPTLIECFIGREDCTEELVKWGK 553 >4COK-A nrPDB Length = 558 Score = 368 bits (943), Expect = e-102, Method: Composition-based stats. Identities = 107/582 (18%), Positives = 211/582 (36%), Gaps = 55/582 (9%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G+ + +++ + F G L + D + + + +E G AEGYARA Sbjct: 4 TVGRYLADRLAQIGLKHHFAVAGDYNLVLLDQLLLNTDMQQIYCSNELNCGFSAEGYARA 63 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEAD------- 205 +G + VT GA + + A+A+ +P+++ +G + GT Sbjct: 64 NGAAAAI-VTFSVGALSAFNALGGAYAENLPVILISGAPNANDHGTGHILHHTLGTTDYG 122 Query: 206 -VVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 + ++R T + + E+ P +I+ A + P +++ +V A P Sbjct: 123 YQLEMARHITCAAESIVAAEDAPAKIDHVIRTALREKK-PAYLEIACNVAGAPCVRPGGI 181 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 L A + + +++ A I + VG+ I A L+ Sbjct: 182 DALLSPPA-------PDEASLKAAVDAALAFIEQRGSVTMLVGSRI-RAAGAQAQAVALA 233 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLD-MLGMHGCATANLAVQNADLIIAVGARFDDRVTG 383 D VTT F ++ P G A AV+ AD +I + F+D T Sbjct: 234 DALGCAVTTMAAAKSFFPEDHPGYRGHYWGEVSSPGAQQAVEGADGVICLAPVFNDYATV 293 Query: 384 NISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKE 443 S + + + + + A ++ ++++ Sbjct: 294 GWSAWP-----------------KGDNVMLVERHAVTVGGVAYAGIDMRDFLTRLAAHTV 336 Query: 444 RSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMW 503 R + A + P + + + +++ + +T G + Sbjct: 337 RRDATA---RGGAYVTPQTPAAAPTAPLNNAEMARQIGALL---TPRTTLTAETGDS-WF 389 Query: 504 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA 563 A + G +G+ +PAA G +A PE + + GD SF +T E++ Sbjct: 390 NAVRMKLPHGARVELEMQWGHIGWSVPAAFGNALAAPERQHVLMVGDGSFQLTAQEVAQM 449 Query: 564 VQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLK-----GLR 618 ++ PV I ++NN + + + ++ Y++ N D+ L E GLR Sbjct: 450 IRHDLPVIIFLINNHGYTI----EVMIHDGPYNNVK--NWDYAGLMEVFNAGEGNGLGLR 503 Query: 619 VKKQEELDAKLKEFVSTK-GPVLLEVEVDKKVPVLPMVAGGS 659 + EL A +++ + + GP L+E +D+ +V G Sbjct: 504 ARTGGELAAAIEQARANRNGPTLIECTLDRDDCTQELVTWGK 545 >6EFG-A nrPDB Length = 563 Score = 363 bits (932), Expect = e-100, Method: Composition-based stats. Identities = 132/584 (22%), Positives = 221/584 (37%), Gaps = 73/584 (12%) Query: 91 GLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYA 150 +T G+ E + + V T+FG PG L + D I+ + +E A + A+GYA Sbjct: 3 EITLGRYLFERLKQVEVQTIFGLPGDFNLSLLDNIYEVPGMRWAGNANELNAAYAADGYA 62 Query: 151 RASGKPGVVLVTSGPGATNVVTPMADAFAD--------GIPMVVFTGQV--PTSAIGTDA 200 R G ++ T G G + + +A ++A+ G+P V + +G Sbjct: 63 RLKGM-SCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSVSSQAKQLLLHHTLGNGD 121 Query: 201 FQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKD-----VTA 255 F +S + ++ M+ + P I+ T PV + LP + V A Sbjct: 122 FTVFH--RMSSNISETTAMITDINTAPAEIDRCIRT-TYVSQRPVYLGLPANLVDLTVPA 178 Query: 256 AILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHAD 315 ++L PI E + I LI AK PV+ A H D Sbjct: 179 SLLDTPIDLS-----------LKPNDPEAEEEVIENVLQLIKEAKNPVILADACCSRH-D 226 Query: 316 GPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLD-MLGMHGCATANLAVQNADLIIAVG 374 K+L D Q P T G GS D++ P+ +G AV++ADL+++VG Sbjct: 227 AKAETKKLIDLTQFPAFVTPMGKGSIDEKHPRFGGVYVGTLSSPAVKEAVESADLVLSVG 286 Query: 375 ARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAV---EGDATTNL 431 A D TG+ S ++ + + I+ F I + + T + Sbjct: 287 ALLSDFNTGSFS-YSYKTKN--------IVEFHSDYTKIRSATFPGVQMKFALQKLLTKV 337 Query: 432 GKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHV 491 PV SE E+ A + TP +K + V ++ + + G V Sbjct: 338 ADAAKGYKPVPVPSE---------PEHNEAVADSTP---LKQEWVWTQVGEFLRE-GDVV 384 Query: 492 IVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVA----KPESLVIDI 547 I TG + N I+ G++G+ A +GA A P+ VI Sbjct: 385 ITETGTSAFGINQTHF---PNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILF 441 Query: 548 DGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIK 607 GD S +T+ E+S+ ++ G + +LNN+ G + +Y+ N ++ Sbjct: 442 IGDGSLQLTVQEISTMIRWGLKPYLFVLNND--GYTIERLIHGETAQYNCIQ--NWQHLE 497 Query: 608 LAEAMGLK---GLRVKKQEELD--AKLKEFVSTKGPVLLEVEVD 646 L G K +RV E + ++F L+EV + Sbjct: 498 LLPTFGAKDYEAVRVSTTGEWNKLTTDEKFQDNTRIRLIEVMLP 541 >2VBF-A nrPDB Length = 570 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 124/584 (21%), Positives = 234/584 (40%), Gaps = 55/584 (9%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T G + + ++ +FG PG L D I + + ++ +E A +MA+GYAR Sbjct: 26 TVGDYLLDRLHELGIEEIFGVPGDYNLQFLDQIISREDMKWIGNANELNASYMADGYAR- 84 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVV-GISR 211 + K L T G G + + +A ++A+ +P+V G + F + G + Sbjct: 85 TKKAAAFLTTFGVGELSAINGLAGSYAENLPVVEIVGSPTSKVQNDGKFVHHTLADGDFK 144 Query: 212 SCTKWNVMVKSVEELPLRINEAFEI-----ATSGRPGPVLVDLPKDVTAAILRNPIPTKT 266 K + V + L N +EI PV ++LP DV AA P + Sbjct: 145 HFMKMHEPVTAARTLLTAENATYEIDRVLSQLLKERKPVYINLPVDVAAAKAEKPALSLE 204 Query: 267 TLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDR 326 S T+ ++ ++ I ++ + A+KPV+ G +++ + + + Sbjct: 205 KESS------TTNTTEQVILSKIEES---LKNAQKPVVIAGHEVISFGL-EKTVTQFVSE 254 Query: 327 AQIPVTTTLQGLGSFDQEDPKSLDML-GMHGCATANLAVQNADLIIAVGARFDDRVTGNI 385 ++P+TT G + D+ P L + G + V++AD I+ +G + D TG Sbjct: 255 TKLPITTLNFGKSAVDESLPSFLGIYNGKLSEISLKNFVESADFILMLGVKLTDSSTGAF 314 Query: 386 SKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERS 445 + E + + GII NKVV+ + ++S + +K Sbjct: 315 THHLDENKMISLNIDEGII--------FNKVVED---------FDFRAVVSSLSELKGIE 357 Query: 446 EWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAA 505 I+K +E+ + P S+ + ++ L++ + ++ G + A Sbjct: 358 YEGQYIDKQYEEFIPS---SAPLSQDRLWQAVESLTQ----SNETIVAEQGTS---FFGA 407 Query: 506 QHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQ 565 ++ FI G++GY PAA+G+Q+A ES + GD S +T+ EL +++ Sbjct: 408 STIFLKSNSRFIGQPLWGSIGYTFPAALGSQIADKESRHLLFIGDGSLQLTVQELGLSIR 467 Query: 566 AGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLR-----VK 620 I+NN+ G + + Y+ N + KL E G R V+ Sbjct: 468 EKLNPICFIINND--GYTVEREIHGPTQSYNDIPMWN--YSKLPETFGATEDRVVSKIVR 523 Query: 621 KQEELDAKLKEF-VSTKGPVLLEVEVDKKVPVLPMVAGGSGLDE 663 + E + +KE +E+ ++K+ + G E Sbjct: 524 TENEFVSVMKEAQADVNRMYWIELVLEKEDAPKLLKKMGKLFAE 567 >1UPC-A nrPDB Length = 573 Score = 361 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 135/566 (23%), Positives = 226/566 (39%), Gaps = 26/566 (4%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARA 152 T + V VFG G + + +FVL +HE AG A+ AR Sbjct: 13 TAAHALLSRLRDHGVGKVFGVVGREAASIL--FDEVEGIDFVLTRHEFTAGVAADVLARI 70 Query: 153 SGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAI-GTDAFQEADVVGISR 211 +G+P T GPG TN+ T +A + D P++ Q + I D Q D V I Sbjct: 71 TGRPQACWATLGPGMTNLSTGIATSVLDRSPVIALAAQSESHDIFPNDTHQCLDSVAIVA 130 Query: 212 SCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSN 271 +K+ V ++ E+ ++ A A + GP + LP D+ + T P+N Sbjct: 131 PMSKYAVELQRPHEITDLVDSAVNAAMTEPVGPSFISLPVDLLGSS-EGIDTTVPNPPAN 189 Query: 272 ALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPV 331 + D + + AA L AK PVL VGA + P ++ L++R IPV Sbjct: 190 TPAKPVGVVADGWQKAADQAAALL-AEAKHPVLVVGAAAIRSGAVPA-IRALAERLNIPV 247 Query: 332 TTTLQGLGSFDQEDPKSLDML-----GMHGCATANLAVQNADLIIAVGARFDDRVTGNIS 386 TT G + + G+ DL++ VG + Sbjct: 248 ITTYIAKGVLPVGHELNYGAVTGYMDGILNFPALQTMFAPVDLVLTVGYDYA-------E 300 Query: 387 KFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSE 446 P + E + I V+P I +V + + V D + + ++ Sbjct: 301 DLRPSMWQKGIEKKTVRISPTVNP--IPRVYRPDVDVVTDVLAFVEHFETATASFG--AK 356 Query: 447 WFAQINKWKKEYPYAYME-ETPGSKIKPQTVIKKLSKVANDTGR--HVIVTTGVGQHQMW 503 I + + ET ++ VI ++ V + + + +G + + Sbjct: 357 QRHDIEPLRARIAEFLADPETYEDGMRVHQVIDSMNTVMEEAAEPGEGTIVSDIGFFRHY 416 Query: 504 AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSA 563 P F+TS G + GYG+PAAIGAQ+A+P+ I GD F+ ++L + Sbjct: 417 GVLFARADQPFGFLTSAGCSSFGYGIPAAIGAQMARPDQPTFLIAGDGGFHSNSSDLETI 476 Query: 564 VQAGTPVKILILNNEEQGMVTQWQSLFYE-HRYSHTHQLNPDFIKLAEAMGLKGLRVKKQ 622 + P+ +++NN+ G++ +Q++ + DF+ LAEA G+ R + Sbjct: 477 ARLNLPIVTVVVNNDTNGLIELYQNIGHHRSHDPAVKFGGVDFVALAEANGVDATRATNR 536 Query: 623 EELDAKLKEFVSTKGPVLLEVEVDKK 648 EEL A L++ P L+EV V+ Sbjct: 537 EELLAALRKGAELGRPFLIEVPVNYD 562 >1QPB-A nrPDB Length = 563 Score = 357 bits (915), Expect = 1e-98, Method: Composition-based stats. Identities = 131/584 (22%), Positives = 221/584 (37%), Gaps = 73/584 (12%) Query: 91 GLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYA 150 +T G+ E + + NV+TVFG PG L + D I+ + + +E A + A+GYA Sbjct: 3 EITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYA 62 Query: 151 RASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVV------FTGQVP----TSAIGTDA 200 R G ++ T G G + + +A ++A+ + ++ + Q +G Sbjct: 63 RIKGM-SCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISAQAKQLLLHHTLGNGD 121 Query: 201 FQEADVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPK-----DVTA 255 F +S + ++ M+ + P I+ T PV + LP +V A Sbjct: 122 FTVFH--RMSANISETTAMITDIATAPAEIDRCIRT-TYVTQRPVYLGLPANLVDLNVPA 178 Query: 256 AILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHAD 315 +L+ PI E + I+ LI AK PV+ A H D Sbjct: 179 KLLQTPIDMS-----------LKPNDAESEKEVIDTILVLIKDAKNPVILADACCSRH-D 226 Query: 316 GPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLD-MLGMHGCATANLAVQNADLIIAVG 374 K+L D Q P T G GS D++ P+ +G AV++ADLI++VG Sbjct: 227 VKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRYGGVYVGTLSKPEVKEAVESADLILSVG 286 Query: 375 ARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIA---VEGDATTNL 431 A D TG+ S ++ + + I+ F I + V T + Sbjct: 287 ALLSDFNTGSFS-YSYKTKN--------IVEFHSDHMKIRNATFPGVQMKFVLQKLLTAI 337 Query: 432 GKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHV 491 PV + + A TP +K + + +L + G V Sbjct: 338 ADAAKGYKPVAVPA---------RTPANAAVPASTP---LKQEWMWNQLGNFLQE-GDVV 384 Query: 492 IVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVA----KPESLVIDI 547 I TG + T+ N I+ G++G+ A +GA A P+ VI Sbjct: 385 IAETGTSA---FGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILF 441 Query: 548 DGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIK 607 GD S +T+ E+S+ ++ G + +LNN+ + + L + + + D + Sbjct: 442 IGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTI----EKLIHGPKAQYNEIQGWDHLS 497 Query: 608 LAEAMGLKGL---RVKKQEELDAKLK--EFVSTKGPVLLEVEVD 646 L G K RV E D + F ++EV + Sbjct: 498 LLPTFGAKDYETHRVATTGEWDKLTQDKSFNDNSKIRMIEVMLP 541 >2Q5O-A nrPDB Length = 565 Score = 348 bits (893), Expect = 4e-96, Method: Composition-based stats. Identities = 118/568 (20%), Positives = 210/568 (36%), Gaps = 50/568 (8%) Query: 95 GQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASG 154 + + + +FG PG LP + + HE G A+ AR S Sbjct: 24 AEALLRALKDRGAQAMFGIPGDFALPFFKVAEETQILPLHTLSHEPAVGFAADAAARYSS 83 Query: 155 KPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEA------DVVG 208 GV VT G GA N+V +A A+A+ P+VV +G T+ Sbjct: 84 TLGVAAVTYGAGAFNMVNAVAGAYAEKSPVVVISGAPGTTEGNAGLLLHHQGRTLDTQFQ 143 Query: 209 ISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTL 268 + + T + + P I A + PV +++P+++ A + P+ Sbjct: 144 VFKEITVAQARLDDPAKAPAEIARVLGAA-RAQSRPVYLEIPRNMVNAEV-EPVGDDPAW 201 Query: 269 PSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQ 328 P + + ++ + A PVL V + + + EL+ R Sbjct: 202 PV----------DRDALAACADEVLAAMRSATSPVLMVCVEVRRYGL-EAKVAELAQRLG 250 Query: 329 IPVTTTLQGLGSF-DQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISK 387 +PV TT G G D P +G+ G A V+ +D + +GA D + Sbjct: 251 VPVVTTFMGRGLLADAPTPPLGTYIGVAGDAEITRLVEESDGLFLLGAILSD------TN 304 Query: 388 FAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEW 447 FA R+ I + ++ V D + + + ER Sbjct: 305 FAVSQRK---------IDLRKTIHAFDRAVTLGYHTYADIP-----LAGLVDALLERLPP 350 Query: 448 FAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQH 507 + + K+ + Y + G I P + + ++ +++ +G A Sbjct: 351 SDRTTRGKEPHAYPTGLQADGEPIAPMDIARAVNDRVRAGQEPLLIAADMGDCLFTAMDM 410 Query: 508 WTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAG 567 + G MG+G+PA IGAQ ++ + GD +F MT EL + + G Sbjct: 411 ID----AGLMAPGYYAGMGFGVPAGIGAQCVSGGKRILTVVGDGAFQMTGWELGNCRRLG 466 Query: 568 TPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEELDA 627 +++ NN M+ +Q E ++ + F +A MG G+RV+ + EL A Sbjct: 467 IDPIVILFNNASWEMLRTFQP---ESAFNDLD--DWRFADMAAGMGGDGVRVRTRAELKA 521 Query: 628 KLKEFVSTKGPV-LLEVEVDKKVPVLPM 654 L + +T+G L+E + + V + Sbjct: 522 ALDKAFATRGRFQLIEAMIPRGVLSDTL 549 >2JLA-A nrPDB Length = 558 Score = 188 bits (476), Expect = 9e-48, Method: Composition-based stats. Identities = 97/581 (16%), Positives = 193/581 (33%), Gaps = 46/581 (7%) Query: 85 MDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGH 144 M S + E ++R V + PG P+ A + F E+G GH Sbjct: 3 MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGH 62 Query: 145 MAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEA 204 +A G A+ S +P V+VTSG N+ + +A G +++ T P I A Q Sbjct: 63 LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAI 122 Query: 205 DVVGISRSCTKWNVMVKSV-EELPLR-----INEAFEIATSGRPGPVLVDLPKDVTA-AI 257 G+ S ++ + +++P R I+ A G V ++ P Sbjct: 123 RQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTL---HAGGVHINCPFAEPLYGE 179 Query: 258 LRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGP 317 + + + + ++ ++S + K+ V+ G A+ Sbjct: 180 MDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAG---RMSAEEG 236 Query: 318 RLLKELSDRAQIPVT--TTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGA 375 + + + P+ Q D G A A +Q A +++ +G+ Sbjct: 237 KKVALWAQTLGWPLIGDVLSQTGQPLPCAD-------LWLGNAKATSELQQAQIVVQLGS 289 Query: 376 RFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMM 435 +++ +A+ E I + ++ + + L Sbjct: 290 --------SLTGKRLLQWQASCEPEEYWI-VDDIEGRLDPAHHRGRRLIANIADWL---- 336 Query: 436 SKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTT 495 ++ P ++R W +I + ++ A + + ++ + G+ Sbjct: 337 -ELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGE--AQLAHRICDYLPEQGQLF---- 389 Query: 496 GVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYG--LPAAIGAQVAKPESLVIDIDGDASF 553 VG + + P + G G L A G Q A + I GD S Sbjct: 390 -VGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRAS-GKPTLAIVGDLSA 447 Query: 554 NMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMG 613 L L+ Q P+ ++++NN + + + E + N F A Sbjct: 448 LYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFE 507 Query: 614 LKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVLPM 654 LK R + +EL+ + T ++E+ V+ + Sbjct: 508 LKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTL 548 >3LQ1-A nrPDB Length = 578 Score = 185 bits (468), Expect = 7e-47, Method: Composition-based stats. Identities = 101/577 (17%), Positives = 189/577 (32%), Gaps = 52/577 (9%) Query: 96 QIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGK 155 F E + + V PG P+ + + E+ AG A G A+AS + Sbjct: 15 AAFIEELVQAGVKEAIISPGSRSTPLALMMAEHPILKIYVDVDERSAGFFALGLAKASKR 74 Query: 156 PGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTK 215 P V+L TSG A N +A+A IP++V T P A Q D + + S K Sbjct: 75 PVVLLCTSGTAAANYFPAVAEANLSQIPLIVLTADRPHELRNVGAPQAMDQLHLYGSHVK 134 Query: 216 --WNVMVKSVEELPLRI-----NEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTL 268 ++ + E LR + A +IA GPV ++ P + P P T Sbjct: 135 DFTDMALPENSEEMLRYAKWHGSRAVDIAMKTPRGPVHLNFPLREPLVPILEPSPFTATG 194 Query: 269 ---PSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSD 325 + D + + + + KK V VG ++ + + + +L+ Sbjct: 195 KKHHHVHIYYTHEVLDDSSIQKMVTECT-----GKKGVFVVGP--IDKKELEQPMVDLAK 247 Query: 326 RAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAV-QNADLIIAVGARFDDRVTGN 384 + P+ DP S G+ + V D + D Sbjct: 248 KLGWPILA-----------DPLS----GLRSYGALDEVVIDQYDAFLKEAEIIDKLTPEV 292 Query: 385 ISKFAP-EARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIF--PV 441 + +F + + + + I D + + I + Sbjct: 293 VIRFGSMPVSKPLKNWLEQLSDIRFYVVDPGAAWKDPIKAVTDMIHCDERFLLDIMQQNM 352 Query: 442 KERSEWFAQINKWKKEYPYAY----MEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGV 497 + ++ A +N W A E + ++ ++ +L ++ D I Sbjct: 353 PDDAKDAAWLNGWTSYNKVAREIVLAEMANTTILEEGKIVAELRRLLPDKAGLFI----- 407 Query: 498 GQHQMW---AAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFN 554 G + + G + + +A+GA V + + GD SF Sbjct: 408 GNSMPIRDVDTYFSQIDKKIKMLANRGANGIDGVVSSALGASVVF--QPMFLLIGDLSFY 465 Query: 555 MTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQLN--PDFIKLAEAM 612 + L A + + I+I+NN+ G+ + + + DF A Sbjct: 466 HDMNGLLMAKKYKMNLTIVIVNNDGGGIFSFLPQANEPKYFESLFGTSTELDFRFAAAFY 525 Query: 613 GLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKV 649 K +EL+ + + KG ++EV+ ++ Sbjct: 526 DADYHEAKSVDELEEAIDKASYHKGLDIIEVKTNRHE 562 >2X7J-A nrPDB Length = 604 Score = 173 bits (438), Expect = 3e-43, Method: Composition-based stats. Identities = 95/578 (16%), Positives = 192/578 (33%), Gaps = 60/578 (10%) Query: 98 FNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPG 157 F + + + PG P+ + + E+ AG A G A+A +P Sbjct: 37 FIDEFALSGITDAVVCPGSRSTPLAVLCAAHPDISVHVQIDERSAGFFALGLAKAKQRPV 96 Query: 158 VVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWN 217 +++ TSG A N + +A +P++V T P A Q + + + K+ Sbjct: 97 LLICTSGTAAANFYPAVVEAHYSRVPIIVLTADRPHELREVGAPQAINQHFLFGNFVKFF 156 Query: 218 VMVKSVEELPLRI-------NEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPS 270 EE P + + A A GPV V++P L + + Sbjct: 157 TDSALPEESPQMLRYIRTLASRAAGEAQKRPMGPVHVNVPL---REPLMPDLSDEPFGRM 213 Query: 271 NALNQLTSRA-QDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRL-LKELSDRAQ 328 ++ + +S++ A+++ A+K ++ G H+D + + LS Q Sbjct: 214 RTGRHVSVKTGTQSVDRESLSDVAEMLAEAEKGMIVCGEL---HSDADKENIIALSKALQ 270 Query: 329 IPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQN------------ADLIIAVGAR 376 P+ DP S G+H +T A + D++I G Sbjct: 271 YPILA-----------DPLSNLRNGVHDKSTVIDAYDSFLKDDELKRKLRPDVVIRFGPM 319 Query: 377 FDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMS 436 + K P ++ + GG P + + + +A+ ++M+ Sbjct: 320 PVSKPVFLWLKDDPTIQQIVIDEDGGW----RDPTQASAHM-----IHCNASVFAEEIMA 370 Query: 437 KIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTT- 495 + SEW + + + + + L + + + + Sbjct: 371 GLTAATRSSEWLEKWQFVNGRFREHLQTISSEDVSFEGNLYRILQHLVPENSSLFVGNSM 430 Query: 496 ---GVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDAS 552 V P ++ G + + +A+G ++ V + GD S Sbjct: 431 PIRDVDTF------FEKQDRPFRIYSNRGANGIDGVVSSAMGVCEGT-KAPVTLVIGDLS 483 Query: 553 FNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHTHQ--LNPDFIKLAE 610 F L L +A + G P+ ++++NN+ G+ + + + DF A Sbjct: 484 FYHDLNGLLAAKKLGIPLTVILVNNDGGGIFSFLPQASEKTHFEDLFGTPTGLDFKHAAA 543 Query: 611 AMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKK 648 G +E G L+E++ D++ Sbjct: 544 LYGGTYSCPASWDEFKTAYAPQADKPGLHLIEIKTDRQ 581 >5ESS-A nrPDB Length = 574 Score = 145 bits (364), Expect = 8e-35, Method: Composition-based stats. Identities = 103/590 (17%), Positives = 194/590 (32%), Gaps = 90/590 (15%) Query: 93 TGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDK---FNFVLPKHEQGAGHMAEGY 149 T ++ + + R V V PG P+ A+ ++D+ + E+ AG++A G Sbjct: 26 TQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGYLAIGL 85 Query: 150 ARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGI 209 A +G P V +TSG N+ + +A +P++V + P +GT A Q + +G Sbjct: 86 AIGAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTMEQLGY 145 Query: 210 SRSCTKWNVMVKSVEELPL---RINEAFEIAT-----------SGRPGPVLVDLPKDVTA 255 + + ++ + E+ P +N + AT + GPV D+P Sbjct: 146 FGTQVRASISLGLAEDAPERTSALNATWRSATCRVLAAATGARTANAGPVHFDIPLREPL 205 Query: 256 AILRNPIPTKTTLPSNALNQLTSRAQDEFVMQ-SINKAADLINLAKKPVLYVGAGILNHA 314 P+ T A T F I+ + D V+ G G H Sbjct: 206 VPDPEPLGAVTPPGRPAGKPWTYTPPVTFDQPLDIDLSVDT-------VVISGHGAGVHP 258 Query: 315 DGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVG 374 + L L + + +H A L Q +I +G Sbjct: 259 N-------------------LAALPTVAEPTAPRSGDNPLHPLALPLLRPQQ---VIMLG 296 Query: 375 ARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKM 434 + P + A ++ G++ + Sbjct: 297 ---------RPTLHRPVSVLLADAEVPVF-------ALTTGPRWPDVS--GNSQATGTRA 338 Query: 435 MSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKP-QTVIKKLSKVANDTGRHVI- 492 ++ P + A +N+ A E+ + V +S + V+ Sbjct: 339 VTTGAPRPAWLDRCAAMNRHA---IAAVREQLAAHPLTTGLHVAAAVSHALRPGDQLVLG 395 Query: 493 VTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQ-----VAKPES--LVI 545 + V + R +G GT+ + AA+ + P+S I Sbjct: 396 ASNPVRDVALAGLDTRGIRVRSNRGVAGIDGTVSTAIGAALAYEGAHERTGSPDSPPRTI 455 Query: 546 DIDGDASFNMTLTELSSAVQAGTP--VKILILNNEEQGMVTQWQSLFYEHRYSHTHQ--- 600 + GD +F + L P + I++ N+ G+ + + R+S Sbjct: 456 ALIGDLTFVHDSSGLLIGPTEPIPRSLTIVVSNDNGGGIFELLEQG--DPRFSDVSSRIF 513 Query: 601 ---LNPDFIKLAEAMGLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDK 647 + D L A ++ R + +EL L + + G +LEV+ D+ Sbjct: 514 GTPHDVDVGALCRAYHVES-RQIEVDELGPTLDQPGA--GMRVLEVKADR 560 >5B47-B nrPDB Length = 304 Score = 56.4 bits (134), Expect = 4e-08, Method: Composition-based stats. Identities = 38/215 (17%), Positives = 71/215 (33%), Gaps = 34/215 (15%) Query: 487 TGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAAIGAQVAKPESLVID 546 + V++ +G+G SG G + A G +++ P VI Sbjct: 34 NPKSVVIVSGIGCSGK-IPHFMNLP------ISGVHTLHGRSIAFATGIKLSNPSLEVIV 86 Query: 547 IDGDA-SFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYEHRYSHT------- 598 GD + + + + +L+ NN G+ Q+ HR T Sbjct: 87 NVGDGDGLGIGMGHFVHLGRRNIDIAVLVHNNGVYGLTKG-QASPTLHRGEKTKSLPKPN 145 Query: 599 --HQLNPDFIKLAEAM----GLKGLRVKKQEELDAKLKEFVSTKGPVLLEVEVDKKVPVL 652 +NP + LA V +EL +K+ + KG L++ + + P Sbjct: 146 IMDAVNPLAVALAAGYTFVARGYAYDVMHLKEL---IKKAILHKGSALVD--ILQPCPTY 200 Query: 653 PMVAGGS-------GLDEFINFDPEVERQQTELRH 680 + LD +DP V +++ + Sbjct: 201 NDINTKEWYDKRVYKLDNVPGWDPVVRKEEEAQKK 235 >3I9V-3 nrPDB Length = 783 Score = 45.6 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 61/204 (29%), Gaps = 36/204 (17%) Query: 282 DEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGL--- 338 D+ + + KA + AK PVL +GAG+L + L++R V Sbjct: 483 DKEGSEMVAKAKEAWEKAKNPVLILGAGVLQDTVAAERARLLAERKGAKVLAMTPAANAR 542 Query: 339 -----GSFD------QEDPKSLDMLGMHGCATANLAVQNADLIIA-------VGARFDDR 380 G ++P +L +G A++ ++ + R+ Sbjct: 543 GLEAMGVLPGAKGASWDEPGAL--YAYYGFVPPEEALKGKRFVVMHLSHLHPLAERYAHV 600 Query: 381 VTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFP 440 V + + EGR +SP I G+A L + Sbjct: 601 VLPAPTFYEKRGHLVNLEGRV----LPLSPAPIEN---------GEAEGALQVLALLAEA 647 Query: 441 VKERSEWFAQINKWKKEYPYAYME 464 + R + + K E Sbjct: 648 LGVRPPFRLHLEAQKALKARKVPE 671 >3CF4-G nrPDB Length = 170 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 8/92 (8%) Query: 290 NKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQED---- 345 AA +I+ AK+P+L VG L+ + + ++S A IP+ T L +D Sbjct: 25 EMAAKIISKAKRPLLMVGTLALD-PELLDRVVKISKAANIPIAATGSSLAVLADKDVDAK 83 Query: 346 PKSLDMLGMHGCATANLAVQ---NADLIIAVG 374 + MLG + + N D+II +G Sbjct: 84 YINAHMLGFYLTDPKWPGLDGNGNYDMIITIG 115 >6N2O-B nrPDB Length = 292 Score = 43.7 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 23/182 (12%), Positives = 58/182 (31%), Gaps = 24/182 (13%) Query: 474 QTVIKKLSKVANDTGRHVIVT-TGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPAA 532 V + ++++ D+ + ++ G + + G G A Sbjct: 36 NGVYRAMAELGIDSTKFAAISGIGCSSRMPYFVDSYKM--------HTLHGRAG---AVA 84 Query: 533 IGAQVAKPESLVIDIDGDA-SFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQW----- 586 G QVA+P+ V+ GD F++ + + + ++++N G+ Sbjct: 85 TGTQVARPDLCVVVAGGDGDGFSIGGGHMPHMARKNVNMTYVLMDNGIYGLTKGQYSPTS 144 Query: 587 --QSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLR---VKKQEELDAKLKEFVSTKGPVLL 641 + Y Y + + G + K ++ +K + +G + Sbjct: 145 RPEMTAYTTPYGGPENP-MNPLLYMLTYGATYVAQAFAGKPKDCAELIKGAMEHEGFAYV 203 Query: 642 EV 643 + Sbjct: 204 NI 205 >5B48-A nrPDB Length = 627 Score = 42.2 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 43/110 (39%), Gaps = 4/110 (3%) Query: 127 NSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVV 186 V + E A +MA G A +G TSGPG + +V + A + +P+V+ Sbjct: 282 KKGTIVVVQAEDELAAINMAIGAA-LTGVRAAT-ATSGPGFSLMVEGLGWAGMNEVPVVI 339 Query: 187 F--TGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAF 234 P++ + T Q + I ++ +V + + +A Sbjct: 340 TYYIRGGPSTGLPTRTAQSDLIFPIFAGHGEFPKIVLASGDHAEAFKDAI 389 >5W21-B nrPDB Length = 226 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 27/213 (12%), Positives = 56/213 (26%), Gaps = 19/213 (8%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSF-NVDPLEQP------AEPSKLAKKLR 80 R + + + R + SP + + A + N PL + A+ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMGYPNASPLLGSSWGGLIHLYTATARNSY 73 Query: 81 AEPDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQ 140 V Q + ++ D F G + Y + + Sbjct: 74 HLQIHKNGHVDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPE 133 Query: 141 GAGH----MAEGYARASGKPGVVLVTSGPGATNVVTPM-------ADAFADGIPMVVFTG 189 + GY LV+ G + M + + IP++ F Sbjct: 134 NCRFQHQTLENGYDVYHSPQYHFLVSLGAAKAAFLPGMNPPPYSQFLSRRNEIPLIHFNT 193 Query: 190 QVPTSAIGT-DAFQEADVVGISRSCTKWNVMVK 221 +P + + E D + + + + Sbjct: 194 PIPRQHTQSAEDDSERDPLNVLKPRARMTPAPA 226 >4MZD-A nrPDB Length = 488 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 17/45 (37%), Gaps = 4/45 (8%) Query: 42 RYYSASPLPASKRPEPAPS-FNVDPLEQP---AEPSKLAKKLRAE 82 R + SP + + A + PL+ A+P ++ + Sbjct: 14 RQHMDSPDLGTDDDDKAMADIGSQPLKNQKVEAQPLLISNSSEKK 58 >1E1H-A nrPDB Length = 287 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 7/39 (17%), Positives = 16/39 (41%), Gaps = 1/39 (2%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNVDPL 66 R + + + R + SP + + A ++ DP+ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMAYK-DPV 51 >3KIA-A nrPDB Length = 387 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 46/140 (32%), Gaps = 17/140 (12%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS-----FNVDPLEQPAEPSKLAKKLRAE 82 R + + + R + SP + + A + F E+P P+ A+ R Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMADIGSEFMSTYHERPLGPASAAEWFRQR 73 Query: 83 -------PDMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVL 135 P D + G + ++ +NV G I + + D+ V Sbjct: 74 SYDYGQFPPEDLARRKRELGLTVSAVLPSRNVADTVGGIIDEIHALNERAPLIDQILVVD 133 Query: 136 PKHEQG-----AGHMAEGYA 150 E G A H AE Y+ Sbjct: 134 ADSEDGTAGVAASHGAEVYS 153 >6G72-G nrPDB Length = 727 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 63/395 (15%), Positives = 124/395 (31%), Gaps = 49/395 (12%) Query: 108 DTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGA 167 T F Y G + + + ++K E + +R +G Sbjct: 289 KTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWE-------DALSRVAGMLQNF-------E 334 Query: 168 TNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELP 227 N V +A D +V + +E + + + N ++ + Sbjct: 335 GNAVAAIAGGLVDAEALVALKDLLNKVDSDNLCTEEIFPTEGAGTDLRSNYLLNTTIAGV 394 Query: 228 LRINEAFEIATSGRPGPVLVD-------LPKDVTAAILRNPIPTKTTLPSNALNQLTSRA 280 + + T+ R L + L D+ A++ +P+ T + L Sbjct: 395 EEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDL--TYRYDHLGDSPKIL 452 Query: 281 QDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGS 340 QD + + +++ AKKP++ +G+ L DG +L +S+ Q TT Sbjct: 453 QD--IASGRHSFCEVLKDAKKPMVVLGSSALQRDDGAAILVAVSNMVQKIRVTTGVAAE- 509 Query: 341 FDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGR 400 N+ + A + A+ + V P Sbjct: 510 ----------------WKVMNILHRIASQVAALDLGYKPGVEAIRKN--PPKMLFLLGAD 551 Query: 401 GGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPY 460 GG I + PK+ V Q GD + ++ E+S + ++ Sbjct: 552 GGCITRQDLPKDCFIVYQGH---HGDVGAPMADVILPGAAYTEKSATYVNTEGRAQQTKV 608 Query: 461 AYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTT 495 A PG + +I+ LS++A T + + Sbjct: 609 AVTP--PGLAREDWKIIRALSEIAGITLPYDTLDQ 641 >2DGA-A nrPDB Length = 565 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 27/79 (34%), Gaps = 11/79 (13%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFN-------VDPLEQPAEPSKLAKKLR 80 R + + + R + SP + + A + + P+ +P ++ K+ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMAGTPSKPAEPIGPVFTKLKPWQIPKRDW 73 Query: 81 AEPDM----DTSFVGLTGG 95 + D TS + G Sbjct: 74 FDKDFLFGASTSAYQIEGA 92 >2OG2-A nrPDB Length = 359 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 5/25 (20%), Positives = 10/25 (40%) Query: 42 RYYSASPLPASKRPEPAPSFNVDPL 66 R + SP + + A + + P Sbjct: 15 RQHMDSPDLGTDDDDKAMACSAGPS 39 >3PK1-A nrPDB Length = 189 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 24/70 (34%), Gaps = 8/70 (11%) Query: 42 RYYSASPLPASKRPEPAPSFNVDPLEQPAEPSKLAKKLRAEPDM---DTSFVGLTGG--Q 96 R + SP + + A + D + ++ + E DT +G +G + Sbjct: 14 RQHMDSPDLGTDDDDKAMA---DIGSLYRQSLEIISRYLREQATGAKDTKPMGRSGATSR 70 Query: 97 IFNEMMSRQN 106 E + R Sbjct: 71 KALETLRRVG 80 >3AIW-A nrPDB Length = 564 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 26/79 (32%), Gaps = 11/79 (13%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFN-------VDPLEQPAEPSKLAKKLR 80 R + + + R + SP + + A + + P+ +P ++ K+ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMAGTPSKPSEPIGPVFTKLKPWQIPKRDW 73 Query: 81 AEPDM----DTSFVGLTGG 95 D TS + G Sbjct: 74 FSKDFLFGASTSAYQIEGA 92 >3KCC-A nrPDB Length = 260 Score = 39.5 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 10/77 (12%), Positives = 24/77 (31%), Gaps = 20/77 (25%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSF---------NVDPLEQ---------- 68 R + + + R + SP + + A + DP + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMADIGSMVLGKPQTDPTLEWFLSHCHIHK 73 Query: 69 -PAEPSKLAKKLRAEPD 84 P++ + + + +AE Sbjct: 74 YPSKSTLIHQGEKAETL 90 >5ZVL-A nrPDB Length = 171 Score = 39.5 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 7/39 (17%), Positives = 16/39 (41%), Gaps = 1/39 (2%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNVDPL 66 R + + + R + SP + + A + + DP+ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMAIS-DPM 51 >5XTU-A nrPDB Length = 360 Score = 38.7 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 19/54 (35%), Gaps = 1/54 (1%) Query: 42 RYYSASPLPASKRPEPAPSFNVDPLEQPAEP-SKLAKKLRAEPDMDTSFVGLTG 94 R + SP + + A D + + S + K DM+ + G G Sbjct: 14 RQHMDSPDLGTDDDDKAMVAEFDRITNFGDSLSDIGNKHMITVDMNQATSGKIG 67 >2AKJ-A nrPDB Length = 608 Score = 38.7 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 19/58 (32%), Gaps = 2/58 (3%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFN--VDPLEQPAEPSKLAKKLRAEP 83 R + + + R + SP + + A V P + A S R EP Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMGCQKAVSPAAETAAVSPSVDAARLEP 71 >3DVA-A nrPDB Length = 369 Score = 38.7 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 45/131 (34%), Gaps = 19/131 (14%) Query: 528 GLPAAIGAQVAKPESLVIDIDGDASFNMT--LTELSSAVQAGTPVKILILNNEEQGMVTQ 585 A+G ++ +++ I GD + ++ A P ++ NN Sbjct: 152 AAGVALGLKMRGKKAVAITYTGDGGTSQGDFYEGINFAGAFKAPAIFVVQNNRFAASTPV 211 Query: 586 WQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEEL------DAKLKEFVSTKGPV 639 + + + A A G+ G++V + L A + ++ +GP Sbjct: 212 EKQTVAKT-----------LAQKAVAAGIPGIQVDGMDPLAVYAAVKAARERAINGEGPT 260 Query: 640 LLEVEVDKKVP 650 L+E + P Sbjct: 261 LIETLCFRYGP 271 >3LY9-A nrPDB Length = 372 Score = 38.3 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 20/55 (36%), Gaps = 8/55 (14%) Query: 42 RYYSASPLPASKRPEPAPS-----FNVDPLEQPAEPSKLAKKLRAEPDMDTSFVG 91 R + SP + + A + + +E S++ R D+D + V Sbjct: 14 RQHMDSPDLGTDDDDKAMAHHHHHHSSGHIEGRHSKSRILLNPR---DIDINMVN 65 >5M85-A nrPDB Length = 215 Score = 38.3 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 5/33 (15%), Positives = 12/33 (36%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS 60 R + + + R + SP + + A + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMA 46 >6C7N-A nrPDB Length = 613 Score = 38.3 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 8/19 (42%) Query: 42 RYYSASPLPASKRPEPAPS 60 R + SP + + A + Sbjct: 14 RQHMDSPDLGTDDDDKAMA 32 >4EM2-A nrPDB Length = 178 Score = 38.3 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 8/19 (42%) Query: 42 RYYSASPLPASKRPEPAPS 60 R + SP + + A + Sbjct: 8 RQHMDSPDLGTDDDDKAMA 26 >4B8O-A nrPDB Length = 490 Score = 38.3 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 8/19 (42%) Query: 42 RYYSASPLPASKRPEPAPS 60 R + SP + + A + Sbjct: 14 RQHMDSPDLGTDDDDKAMA 32 >5B48-B nrPDB Length = 305 Score = 38.3 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 29/178 (16%), Positives = 64/178 (35%), Gaps = 25/178 (14%) Query: 518 TSGGLGTMGYGLPAAIGAQVAKPESLV-IDIDGDASFNMTLTELSSAVQAGTPVKILILN 576 SG G + A G +++ P+ +V ++ + +A + + +++ + Sbjct: 58 ISGVHTLHGRAIAFATGIKLSNPDLVVIVNGGDGDLLGIGAGHFVAAGRRNVDMVVILHD 117 Query: 577 NEEQGMVTQWQSLFYE--------HRYSHTHQLNPDFIKLAEAM----GLKGLRVKKQEE 624 N G+ S + R + +NP + ++ VK +E Sbjct: 118 NGVYGLTKGQASPTLKRGEKPKSLPRPNINDAVNPIALAISSGYTFVARGYAYDVKHLKE 177 Query: 625 LDAKLKEFVSTKGPVLLEVEVDKKVPVLPMVAGGS-------GLDEFINFDPEVERQQ 675 L +K + KG L++V + P + LD ++DP V++ + Sbjct: 178 L---IKSAIKHKGLALIDVL--QPCPTYNDINTKEWYDKRIYKLDTLPDWDPVVKKPE 230 >2G0Y-A nrPDB Length = 184 Score = 38.3 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 4/22 (18%), Positives = 8/22 (36%) Query: 42 RYYSASPLPASKRPEPAPSFNV 63 R + SP + + A + Sbjct: 27 RQHMDSPDLGTDDDDKAMAMVT 48 >5XJN-A nrPDB Length = 455 Score = 38.3 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 5/33 (15%), Positives = 12/33 (36%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS 60 R + + + R + SP + + A + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMA 46 >5YPT-A nrPDB Length = 429 Score = 38.3 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 8/19 (42%) Query: 42 RYYSASPLPASKRPEPAPS 60 R + SP + + A + Sbjct: 14 RQHMDSPDLGTDDDDKAMA 32 >5ER0-A nrPDB Length = 518 Score = 37.9 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 5/33 (15%), Positives = 12/33 (36%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS 60 R + + + R + SP + + A + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMA 46 >6MRG-A nrPDB Length = 580 Score = 37.9 bits (86), Expect = 0.015, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 16/46 (34%), Gaps = 4/46 (8%) Query: 42 RYYSASPLPASKRPEPAPSFNVDPLEQPAEPSKLAKKLRAEPDMDT 87 R + SP + + A + Q A + + + ++T Sbjct: 14 RQHMDSPDLGTDDDDKAM----ETGRQKARGAATRARQKQRASLET 55 >3E46-A nrPDB Length = 253 Score = 37.5 bits (85), Expect = 0.017, Method: Composition-based stats. Identities = 5/33 (15%), Positives = 12/33 (36%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS 60 R + + + R + SP + + A + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMA 46 >4PHT-A nrPDB Length = 500 Score = 37.5 bits (85), Expect = 0.021, Method: Composition-based stats. Identities = 32/218 (14%), Positives = 70/218 (32%), Gaps = 27/218 (12%) Query: 157 GVVLVTSGPGA---TNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSC 213 G++LVT G+ T + + + ++ + + + E D+ GI ++ Sbjct: 255 GIILVTGPTGSGKSTTLYAGLQELNSN-----------ERNILTVEDPIEFDIDGIGQTQ 303 Query: 214 TKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPTK-----TTL 268 V + P V+V +D+ A + +TL Sbjct: 304 VNPKVDMT--------FARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTL 355 Query: 269 PSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQ 328 +N +R +D + + ++ L LA++ V + + + ++L + Sbjct: 356 HTNTAVGAITRLRDMGIEPFLISSSLLGVLAQRLVRTLCQDCKEPYEADKEQRKLFGAKK 415 Query: 329 IPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQN 366 T + G G+H + VQ Sbjct: 416 KDALTLYRAKGCEKCNHKGYRGRTGIHELLMVDDKVQE 453 >1YTL-A nrPDB Length = 174 Score = 37.2 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 49/135 (36%), Gaps = 24/135 (17%) Query: 280 AQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLG 339 + +++ A++I AK+P+L VG + + + +K+ ++ I V T + Sbjct: 16 PKMATLLEKGKPVANMIKKAKRPLLIVGPDMTD--EMFERVKKFVEK-DITVVATGSAIT 72 Query: 340 SFDQEDPKSLDMLGMHGCATANLAVQ--------------NADLIIAVGARFDDRVT--G 383 F + A + Q N DL++ +G+ + Sbjct: 73 RF-----IDAGLGEKVNYAVLHELTQFLLDPDWKGFDGQGNYDLVLMLGSIYYHGSQMLA 127 Query: 384 NISKFAPEARRAAAE 398 I FAP R A + Sbjct: 128 AIKNFAPHIRALAID 142 >2YAD-A nrPDB Length = 171 Score = 37.2 bits (84), Expect = 0.023, Method: Composition-based stats. Identities = 4/19 (21%), Positives = 8/19 (42%) Query: 42 RYYSASPLPASKRPEPAPS 60 R + SP + + A + Sbjct: 14 RQHMDSPDLGTDDDDKAMA 32 >3QRQ-A nrPDB Length = 267 Score = 37.2 bits (84), Expect = 0.023, Method: Composition-based stats. Identities = 5/33 (15%), Positives = 12/33 (36%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS 60 R + + + R + SP + + A + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKAMA 46 >3ZHS-A nrPDB Length = 868 Score = 37.2 bits (84), Expect = 0.024, Method: Composition-based stats. Identities = 34/191 (17%), Positives = 66/191 (34%), Gaps = 19/191 (9%) Query: 205 DVVGISRSCTKWNVMVKSVEELPLRINEAFEIATSGRPGPVLVDLPKDVTAAILRNPIPT 264 +V + + + + V++ +++P ++ A + A R G + LP+ T P+ Sbjct: 447 EVRELEKHEIEPSESVEADQQIPSKLATAVDKAMLQRIGDAHLALPEGFTVHPRVRPVLE 506 Query: 265 KTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 K ++ + ++ + LI K V G R + Sbjct: 507 KR-------REMAYEGRIDWAFAELLALGSLIAEGKL-VRLSGQDTQRGTFTQRHAVIVD 558 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLA---------VQNADLIIAVGA 375 + T LQ L + P + ++ A + A V N D ++ A Sbjct: 559 RKTGEEFTP-LQLLATNPDGTP-TGGKFLVYNSALSEFAAVGFEYGYSVGNPDAMVLWEA 616 Query: 376 RFDDRVTGNIS 386 +F D V G S Sbjct: 617 QFGDFVNGAQS 627 >5B46-A nrPDB Length = 628 Score = 37.2 bits (84), Expect = 0.028, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 126 HNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMV 185 V + E A +MA G A +G TSGPG + + ++ A + +P+V Sbjct: 281 LRKGGVVVVQAEDELAAINMAVGAA-LTGVRSAT-ATSGPGFSLMSEGISWAGMNEVPVV 338 Query: 186 VF 187 + Sbjct: 339 IT 340 >3HMP-A nrPDB Length = 342 Score = 36.4 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 12/33 (36%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS 60 R + + + R + SP + + A S Sbjct: 13 RGSGMKETAAAKFERQHMDSPDLGTDDDDKASS 45 >2ZMD-A nrPDB Length = 390 Score = 36.4 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 12/33 (36%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPS 60 R + + + R + SP + + A S Sbjct: 13 RGSGMKETAAAKFERQHMDSPDLGTDDDDKASS 45 >5GPN-Y nrPDB Length = 727 Score = 36.0 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 38/231 (16%), Positives = 76/231 (32%), Gaps = 28/231 (12%) Query: 269 PSNALNQLTSRAQDEFVMQSINK----AADLINLAKKPVLYVGAGILNHADGPRLLKELS 324 P + + ++Q I + ++ AKKP++ +G+ L +DG +L Sbjct: 435 PVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGSSALQRSDGTAIL---- 490 Query: 325 DRAQIPVTTTLQGLGSFDQEDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGN 384 + + Q S + G N+ + A + A+ + V Sbjct: 491 -----------AAVSNIAQNIRLSSGVTG--DWKVMNILHRIASQVAALDLGYKPGVEAI 537 Query: 385 ISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIAVEGDATTNLGKMMSKIFPVKER 444 P GG I + PK+ + Q GD + ++ E+ Sbjct: 538 RKN--PPKVLFLLGADGGCITRQDLPKDCFIIYQGH---HGDVGAPMADVILPGAAYTEK 592 Query: 445 SEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTT 495 S + ++ A PG + +I+ LS++A T + + Sbjct: 593 SATYVNTEGRAQQTKVAVTP--PGLAREDWKIIRALSEIAGMTLPYDTLDQ 641 >1X7Z-A nrPDB Length = 400 Score = 35.6 bits (80), Expect = 0.076, Method: Composition-based stats. Identities = 27/166 (16%), Positives = 50/166 (30%), Gaps = 26/166 (15%) Query: 529 LPAAIGAQVAKP----ESLVIDIDGDASFNM--TLTELSSAVQAGTPVKILILNNEEQGM 582 +P A+GA A +VI G+ + + + A P+ NN Sbjct: 168 IPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNG---- 223 Query: 583 VTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEEL------DAKLKEFVSTK 636 ++R P G+ +RV + + V+ Sbjct: 224 YAISTPTSEQYRGDGIAARGP-------GYGIMSIRVDGNDVFAVYNATKEARRRAVAEN 276 Query: 637 GPVLLEVEVDKKVPVLP--MVAGGSGLDEFINFDPEVERQQTELRH 680 P L+E + + +DE +D + + + LRH Sbjct: 277 QPFLIEAMTYRIGHHDTSDDSSAYRSVDEVNYWDKQ-DHPISRLRH 321 >3N6R-B nrPDB Length = 531 Score = 35.2 bits (79), Expect = 0.092, Method: Composition-based stats. Identities = 29/217 (13%), Positives = 61/217 (28%), Gaps = 26/217 (11%) Query: 156 PGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTK 215 P P T+ + + D+ + TG + + ++ G + K Sbjct: 187 PCAGGAVYSPAMTDFIFMVKDSSY-----MFVTGPDVVKTVTNEQVSAEELGGATTHTRK 241 Query: 216 WNVMVKSVEELPLRINEAFEIA-------TSGRPGPVLVDLPKDVTAAILRNPIPTKTTL 268 +V + E + E + P D P D L +P Sbjct: 242 SSVADAAFENDVEALAEVRRLVDFLPLNNREKPPVRPFFDDP-DRIEPSLDTLVPDNPNT 300 Query: 269 PSNALNQLTSRAQDEFVMQSINKAADLINL-------------AKKPVLYVGAGILNHAD 315 P + + A + + + A I A +P++ G ++ + Sbjct: 301 PYDMKELIHKLADEGDFYEIQEEFAKNIITGFIRLEGRTVGVVANQPLVLAGCLDIDSSR 360 Query: 316 GPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDML 352 D +IP+ T + G + ++ Sbjct: 361 KAARFVRFCDAFEIPLLTLIDVPGFLPGTSQEYGGVI 397 >5YNL-A nrPDB Length = 362 Score = 35.2 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 6/48 (12%), Positives = 14/48 (29%), Gaps = 1/48 (2%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNVDPLEQPAEPSKL 75 R + + + R + SP + + S P + + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDK-MSPATSPFLATPRTAGI 60 >1IK6-A nrPDB Length = 369 Score = 34.8 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 49/345 (14%), Positives = 97/345 (28%), Gaps = 58/345 (16%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNVDPLEQPAEPSKLAKKLRAEPDMDT 87 R + + + R + SP + + + V + A+ +A E D Sbjct: 13 RGSGMKETAAAKFERNHMDSPDLGTDDDDKMVA-GVVMMANMAKAINMALHEEMERDERV 71 Query: 88 SFVGLTGGQ-----IFNEMM-SRQN----VDT------VFGYPGGAILPVYDAIHNSDKF 131 +G G+ + E + R +DT + G+ G + + Sbjct: 72 VVLGEDVGKKGGVFLVTEGLYERFGPERVIDTPLNEGGILGFAMGMAMAGLKPVAEIQFV 131 Query: 132 NFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFAD-----GIPMVV 186 +F+ ++ H+A+ R+ G LV P + + + + P +V Sbjct: 132 DFIWLGADELLNHIAKLRYRSGGNYKAPLVVRTPVGSGTRGGLYHSNSPEAIFVHTPGLV 191 Query: 187 FT---------GQVPTSAIGTDAFQEADVVGISR------SCTKWNVMVKSVEEL----- 226 G + + G D + + R + V + Sbjct: 192 VVMPSTPYNAKGLLKAAIRGDDPVVFLEPKILYRAPREEVPEGDYVVEIGKARVAREGDD 251 Query: 227 ------PLRINEAFEIATSGRPGPVLVDL----PKDVTAAILRNPIPTKTTLPSNALNQL 276 +++A E A + +VDL P D + + L + Sbjct: 252 VTLVTYGAVVHKALEAAERVKASVEVVDLQTLNPLDFDTVL--KSVSKTGRLIIAHDSPK 309 Query: 277 TSRAQDEFVMQSINKAADLINLAKKPVL-YVGAGILNHADGPRLL 320 T E KA D + PV+ G + Sbjct: 310 TGGLGAEVRALVAEKALDRLTA---PVIRLAGPDVPQSPIAADAA 351 >1UM9-A nrPDB Length = 367 Score = 34.8 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 48/142 (33%), Gaps = 19/142 (13%) Query: 517 ITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLT--ELSSAVQAGTPVKILI 574 + S + AAI ++ + + + GD + + ++ A G P + Sbjct: 142 VASPIASHVPPAAGAAISMKLLRTGQVAVCTFGDGATSEGDWYAGINFAAVQGAPAVFIA 201 Query: 575 LNNEEQGMVTQWQSLFYEHRYSHTHQLNPDFIKLAEAMGLKGLRVKKQEEL------DAK 628 NN + ++ + P A A G+ G V + L Sbjct: 202 ENN-FYAISVDYRHQTHS----------PTIADKAHAFGIPGYLVDGMDVLASYYVVKEA 250 Query: 629 LKEFVSTKGPVLLEVEVDKKVP 650 ++ +GP L+E+ V + P Sbjct: 251 VERARRGEGPSLVELRVYRYGP 272 >5LUC-A nrPDB Length = 403 Score = 34.8 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 46/132 (34%), Gaps = 11/132 (8%) Query: 475 TVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFI--TSGGLGTMGYGLPAA 532 + + + V +V +G G + AA +F+ +G G + Sbjct: 70 EIKEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGER 129 Query: 533 IGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILNNEEQGMVTQWQSLFYE 592 IGA V + D + TL E+ + PV + + + E V Q F E Sbjct: 130 IGA-------RVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGE 182 Query: 593 --HRYSHTHQLN 602 HRY +N Sbjct: 183 LCHRYKCLLLVN 194 >5T5M-B nrPDB Length = 432 Score = 34.5 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 25/144 (17%), Positives = 49/144 (34%), Gaps = 12/144 (8%) Query: 287 QSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQ---GLGSFDQ 343 ++I+KAA ++ +K+P L G + + EL++ A + T G Sbjct: 69 EAIDKAAKILAESKRP-LMYGWSCTE-CEAQAVGVELAEEAGAVIDNTASVCHGPSVLAL 126 Query: 344 EDPKSLDMLGMHGCATANLAVQNADLIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGI 403 +D + N AD+++ G ++S+ GR Sbjct: 127 QD---VGYPICTFGEVKNR----ADVVVYWGCNPMHAHPRHMSRNVFARGFFRERGRSDR 179 Query: 404 IHFEVSPKNINKVVQTQIAVEGDA 427 V P+ + I ++ D Sbjct: 180 TLIVVDPRKTDSAKLADIHLQLDF 203 >4LZZ-A nrPDB Length = 268 Score = 34.1 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 39/227 (17%), Positives = 73/227 (32%), Gaps = 12/227 (5%) Query: 282 DEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQG---L 338 + M+ I + I+ A+ PVL G + RL+ +LSDR++ P Sbjct: 23 ESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPR 82 Query: 339 GSFDQEDPKS--LDMLGMHGCATANLAVQNADLIIA--VGARFDDRVTGNISKFAPEARR 394 F+ E G + + + +G + + + Sbjct: 83 DIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIG-ELSLEAQAKLLRVIESGKF 141 Query: 395 AAAEGRGGIIHFEVSPKNINKVVQTQI---AVEGDATTNLGKMMSKIFPVKERSEW-FAQ 450 GR I N+ ++ + D LG + +I P++ER E Sbjct: 142 YRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPL 201 Query: 451 INKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGV 497 N + K++ Y +E G Q ++ N ++ V Sbjct: 202 ANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAV 248 >1NY5-A nrPDB Length = 387 Score = 34.1 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 39/227 (17%), Positives = 73/227 (32%), Gaps = 12/227 (5%) Query: 282 DEFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQG---L 338 + M+ I + I+ A+ PVL G + RL+ +LSDR++ P Sbjct: 142 ESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPR 201 Query: 339 GSFDQEDPKS--LDMLGMHGCATANLAVQNADLIIA--VGARFDDRVTGNISKFAPEARR 394 F+ E G + + + +G + + + Sbjct: 202 DIFEAELFGYEKGAFTGAVSSKEGFFELADGGTLFLDEIG-ELSLEAQAKLLRVIESGKF 260 Query: 395 AAAEGRGGIIHFEVSPKNINKVVQTQI---AVEGDATTNLGKMMSKIFPVKERSEW-FAQ 450 GR I N+ ++ + D LG + +I P++ER E Sbjct: 261 YRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPL 320 Query: 451 INKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRHVIVTTGV 497 N + K++ Y +E G Q ++ N ++ V Sbjct: 321 ANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAV 367 >2A1T-A nrPDB Length = 421 Score = 34.1 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 40/105 (38%), Gaps = 6/105 (5%) Query: 35 RFYSSSSRYYSASPLPASKRP-EPAPSFNVDPLEQPAEPSKLAKKLRAEPDMDTSFVGLT 93 R S SR++ S + R EP F+ + EQ E A+K E + + Sbjct: 10 RVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDK 69 Query: 94 GGQIFNEMMSR---QNV--DTVFGYPGGAILPVYDAIHNSDKFNF 133 G+ ++ R + + GG L +DA S++ + Sbjct: 70 TGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAY 114 >4B7O-A nrPDB Length = 745 Score = 34.1 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 31/105 (29%), Gaps = 24/105 (22%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEP----------------------APSFNVDP 65 R + + + R + SP + + N+ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKMAENNAKVVLDTVTVKGDRQGSKIRTNIVT 73 Query: 66 LEQPAEPSKLAKK--LRAEPDMDTSFVGLTGGQIFNEMMSRQNVD 108 L+Q E + + L+ EP +D T + M + +VD Sbjct: 74 LQQKDESTATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVD 118 >4AIP-A nrPDB Length = 742 Score = 34.1 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 31/105 (29%), Gaps = 24/105 (22%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEP----------------------APSFNVDP 65 R + + + R + SP + + N+ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDKMAENNAKVVLDTVTVKGDRQGSKIRTNIVT 73 Query: 66 LEQPAEPSKLAKK--LRAEPDMDTSFVGLTGGQIFNEMMSRQNVD 108 L+Q E + + L+ EP +D T + M + +VD Sbjct: 74 LQQKDESTATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVD 118 >4QRX-A nrPDB Length = 363 Score = 34.1 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 5/36 (13%), Positives = 13/36 (36%), Gaps = 1/36 (2%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEPAPSFNV 63 R + + + R + SP + + F++ Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDK-MDFSI 48 >6IBP-A nrPDB Length = 420 Score = 33.7 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 4/30 (13%), Positives = 10/30 (33%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEP 57 R + + + R + SP + + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDK 43 >6N2O-A nrPDB Length = 573 Score = 33.7 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 39/107 (36%), Gaps = 4/107 (3%) Query: 130 KFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTG 189 + V + E + G + A K + TSGPG + + A P +V Sbjct: 244 GGDLVQAEDEIASIAQVLGASYAGKKS--MTATSGPGLALMSEMLGMAHMSETPCLVVDV 301 Query: 190 QV--PTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAF 234 Q P++ + T Q + I +V SVE++ I+ Sbjct: 302 QRGGPSTGLPTKHEQSDLFLAIHGGHGDSPRIVLSVEDVKDCISMTV 348 >3DC2-A nrPDB Length = 529 Score = 33.7 bits (75), Expect = 0.30, Method: Composition-based stats. Identities = 51/304 (16%), Positives = 98/304 (32%), Gaps = 18/304 (5%) Query: 115 GGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGYARASGKPGVVLVTSGPGATNVVTPM 174 G +L + D + +D + LPK + AG + + A A KPGV++V + G + Sbjct: 184 GIELLSLDDLLARADFISVHLPKTPETAGLI-DKEALAKTKPGVIIVNAARGGLVDEAAL 242 Query: 175 ADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGISRSCTKWNVMVKSVEELPLRINEAF 234 ADA G T E V ++ + + E+ Sbjct: 243 ADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQD--RAGTDVAESV 300 Query: 235 EIATSGRPGPVLVDLPKDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQSINKAAD 294 +A +G P V++ V + + L L DE + + Sbjct: 301 RLALAGEFVPDAVNVGGGVVNEEVAPWLDLVRKLGV-----LAGVLSDELPVSLSVQVRG 355 Query: 295 LINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLGM 354 + + VL + A + P +G+ + + +S + + Sbjct: 356 ELAAEEVEVLRLSALRGLFSAVIEDAVTF---VNAPALAAERGVTAEICKASESPNHRSV 412 Query: 355 HGCATANLAVQNAD--LIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKN 412 AD ++ G + +++ I + A+G IIH+ P Sbjct: 413 VDVRAV-----GADGSVVTVSGTLYGPQLSQKIVQINGRHFDLRAQGINLIIHYVDRPGA 467 Query: 413 INKV 416 + K+ Sbjct: 468 LGKI 471 >1M93-B nrPDB Length = 245 Score = 33.3 bits (74), Expect = 0.33, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 21/68 (30%), Gaps = 5/68 (7%) Query: 84 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAIL-----PVYDAIHNSDKFNFVLPKH 138 D+ +TG + + + + VFG G DA+ + + Sbjct: 177 DVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNSDVSVDAMIHKTYIDVNEEYT 236 Query: 139 EQGAGHMA 146 E A A Sbjct: 237 EAAAATSA 244 >1C8O-A nrPDB Length = 300 Score = 33.3 bits (74), Expect = 0.33, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 21/68 (30%), Gaps = 5/68 (7%) Query: 84 DMDTSFVGLTGGQIFNEMMSRQNVDTVFGYPGGAIL-----PVYDAIHNSDKFNFVLPKH 138 D+ +TG + + + + VFG G DA+ + + Sbjct: 232 DVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNSDVSVDAMIHKTYIDVNEEYT 291 Query: 139 EQGAGHMA 146 E A A Sbjct: 292 EAAAATSA 299 >5CFZ-A nrPDB Length = 305 Score = 33.3 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 4/30 (13%), Positives = 10/30 (33%) Query: 28 RSVALAQRFYSSSSRYYSASPLPASKRPEP 57 R + + + R + SP + + Sbjct: 14 RGSGMKETAAAKFERQHMDSPDLGTDDDDK 43 >3BC1-A nrPDB Length = 195 Score = 32.5 bits (72), Expect = 0.64, Method: Composition-based stats. Identities = 8/52 (15%), Positives = 19/52 (36%), Gaps = 4/52 (7%) Query: 293 ADLINLAKKPVLYVGAGILN----HADGPRLLKELSDRAQIPVTTTLQGLGS 340 + ++ P + + + A +EL+++ IP T G+ Sbjct: 119 LQMHAYSENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGT 170 >5J7Z-A nrPDB Length = 500 Score = 32.5 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 27/201 (13%), Positives = 55/201 (27%), Gaps = 20/201 (9%) Query: 357 CATANLAVQNADLII-----AVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPK 411 A+ AD++ + ++ + P+A R + + + Sbjct: 282 APPVTPALTTADVVFAPHDYCIPSQLAIYLG------LPQALRGLCVPQQDLTWSNIDAI 335 Query: 412 NINKVVQTQIAVEGDATTNLGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKI 471 V T I GD + K + + ER W+ + A P Sbjct: 336 TERANVPTVITSFGDGDPTVLK--NTLARADER------FIGWQYWHFGAGNATDPFLGE 387 Query: 472 KPQTVIKKLSKVANDTGRHVIVTTGVGQHQMWAAQHWTWRNPHTFITSGGLGTMGYGLPA 531 + +++ + +I G P S GY + Sbjct: 388 VGRQLVRTYPQATAGEPGRMIFDADNGDFAYRFTPRA-ATRPTEIFVSDLHYPDGYAVQV 446 Query: 532 AIGAQVAKPESLVIDIDGDAS 552 G + P + ++ + D S Sbjct: 447 DGGQVTSAPGARIVTVVADGS 467 >5IHS-A nrPDB Length = 347 Score = 32.5 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 12/132 (9%) Query: 19 IAYRNTPAMRSVALAQRFYSSSSRYYSASPLP---ASKRPEPAPSFNVDPLEQPAEPSKL 75 I Y + A ++ A AQRF+S ++ Y P P A S+N D +P + Sbjct: 122 IDYHSHEAQKNPAAAQRFFSEMAKKYGNIPNIIYEVYNEPLQATSWNKD--IKPYAEGVI 179 Query: 76 AKKLRAEPDMDTSFVGLT-GGQIFNEM----MSRQNVD-TVFGYPGGAILPVYDAIHNSD 129 K+R + VG Q+ E ++RQN+ T+ YPG + + + Sbjct: 180 T-KIRVYDTTNIIVVGTRQWSQLVTEAAANPITRQNIMYTLHFYPGTHKQELRNEAQKAL 238 Query: 130 KFNFVLPKHEQG 141 L E G Sbjct: 239 DMGIALFVTEYG 250 >2FQ1-A nrPDB Length = 287 Score = 32.1 bits (71), Expect = 0.78, Method: Composition-based stats. Identities = 28/202 (13%), Positives = 61/202 (30%), Gaps = 12/202 (5%) Query: 318 RLLKELSDRAQIPVTTTLQGLGSFDQEDPKSLDMLG------MHGCATANLAVQNADLII 371 L++ + IPV T Q D++ DM G + +AD + Sbjct: 63 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 122 Query: 372 AVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIA-VEGDATTN 430 V R+ + + E+ R G H + ++ + DA + Sbjct: 123 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 182 Query: 431 LGKMMSKIFPVKERSEWFAQINKWKKEYPYAYMEETPGSKIKPQTVIKKLSKVANDTGRH 490 + + +K + ++ ++ P + ++ L + Sbjct: 183 FSRDEH-LMSLKYVAGRSGRVVMTEELLPAPIPASKAALREV---ILPLLDESDEPFDDD 238 Query: 491 VIVTTGVGQHQMWAAQHWTWRN 512 ++ G+ +M A WR Sbjct: 239 NLIDYGLDSVRM-MALAARWRK 259 >5BTR-A nrPDB Length = 397 Score = 31.8 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 2/70 (2%) Query: 251 KDVTAAILRNPIPTKTTLPSNALNQLTSRAQDEFVMQS--INKAADLINLAKKPVLYVGA 308 KD+ + P TL +N L+ + + I A L+ +KK ++ GA Sbjct: 63 KDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQESKKIIVLTGA 122 Query: 309 GILNHADGPR 318 G+ + P Sbjct: 123 GVSVSSGIPD 132 >4MB2-A nrPDB Length = 261 Score = 31.4 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 20/47 (42%), Gaps = 2/47 (4%) Query: 283 EFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQI 329 E +++ A + LA+ PV+ V + A P+ EL+ Sbjct: 53 EPAERAMRAAVAKLLLAENPVVSVNGNV--AALVPKETIELARALNA 97 >1E5X-A nrPDB Length = 486 Score = 31.4 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 16/45 (35%), Gaps = 2/45 (4%) Query: 293 ADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQIPVTTTLQG 337 + + K+PV VG G + D L A IP L Sbjct: 174 VNRLRKMKRPV--VGVGCASTGDTSAALSAYCASAGIPSIVFLPA 216 >6GCS-A nrPDB Length = 728 Score = 31.0 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 16/28 (57%) Query: 291 KAADLINLAKKPVLYVGAGILNHADGPR 318 + +++ AK P++ VG+GI + D Sbjct: 469 EFGEVLKNAKNPLIIVGSGITDREDAGA 496 >1G3Q-A nrPDB Length = 237 Score = 30.6 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 53/146 (36%), Gaps = 18/146 (12%) Query: 517 ITSGGLGTMGYGLPAAIGAQVAKPESLVIDIDGDASFNMTLTELSSAVQAGTPVKILILN 576 I SG GT + A + + V+ +DGD +T+ LS + P L Sbjct: 7 IVSGKGGTGKTTVTANLSVALGDRGRKVLAVDGD----LTMANLSLVLGVDDPDVTL--- 59 Query: 577 NEEQGMVTQWQSLFYEHRYSHTHQLN--PDFIKLAEAMGLKGLRVKKQEELDAKLKEFVS 634 ++ + Y ++ + + L D+ + +A +K E+ LK+ Sbjct: 60 HDVLAGEANVEDAIYMTQFDNVYVLPGAVDWEHVLKA------DPRKLPEVIKSLKDKFD 113 Query: 635 TKGPVLLEVEVDKKVPVLPMVAGGSG 660 +L++ ++ + + G Sbjct: 114 F---ILIDCPAGLQLDAMSAMLSGEE 136 >6GUA-A nrPDB Length = 822 Score = 30.6 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 16/29 (55%) Query: 523 GTMGYGLPAAIGAQVAKPESLVIDIDGDA 551 G +GY L A GA + +PE + + GD Sbjct: 146 GELGYVLSHATGAILDQPEQIAFAVVGDG 174 >3WDK-A nrPDB Length = 261 Score = 30.2 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 19/47 (40%), Gaps = 2/47 (4%) Query: 283 EFVMQSINKAADLINLAKKPVLYVGAGILNHADGPRLLKELSDRAQI 329 E +++ A LA+ PV+ V + A P+ EL+ Sbjct: 53 EPAERAMRAAVAKFLLAEHPVISVNGNV--AALVPKETIELAKALNA 97 >1RVG-A nrPDB Length = 305 Score = 29.8 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 14/32 (43%) Query: 610 EAMGLKGLRVKKQEELDAKLKEFVSTKGPVLL 641 E G+ V E L A L+ + PV+L Sbjct: 15 EGYGVGAFNVNNMEFLQAVLEAAEEQRSPVIL 46 >3CZB-A nrPDB Length = 351 Score = 29.4 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 32/234 (13%), Positives = 64/234 (27%), Gaps = 31/234 (13%) Query: 210 SRSCTKWNVMVKSVEELPLRINEAF-------EIATSGRPGPVLVDLPKDVTAAILRNPI 262 +++ + N V++V+ + A+ ++ + L LP D+ + Sbjct: 60 AKAFIEANFRVEAVDGGGDGLLTAYFAPQYEARMSRNAEFSAPLRGLPADLVV------L 113 Query: 263 PTKTTLPSNALNQLTSRAQDEFVMQSINKAADLINLAKKPVL-----------YVGAGIL 311 P+ ++T + + ++A + KP+ G+G+L Sbjct: 114 DLGPFEPALVGKKITGHVEGSTFVPYPDRAEIEATPSDKPLAWMRPEELFFLQIQGSGVL 173 Query: 312 NHADGPRLLKELSDRAQIPVTTTLQG---LGSFDQEDPKSLDMLGMHGCATANLAVQNAD 368 DG R+ + P G + A AD Sbjct: 174 VLPDGRRVRAVFAGTNGKPFVGIAIAMRDKGLLPDNN----TSADAIRTWLAEHRGPEAD 229 Query: 369 LIIAVGARFDDRVTGNISKFAPEARRAAAEGRGGIIHFEVSPKNINKVVQTQIA 422 I+ + R+ T P A G I + A Sbjct: 230 AIMRLNPRYVFFRTVPDDGKEPAGAAGVALPPGRAIAVDPGYHAYGGFYWLDAA 283 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.118 0.276 Lambda K H 0.267 0.0360 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,147,988 Number of Sequences: 36641 Number of extensions: 795342 Number of successful extensions: 3218 Number of sequences better than 10.0: 108 Number of HSP's better than 10.0 without gapping: 111 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 2800 Number of HSP's gapped (non-prelim): 177 length of query: 687 length of database: 10,336,785 effective HSP length: 104 effective length of query: 583 effective length of database: 6,526,121 effective search space: 3804728543 effective search space used: 3804728543 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.7 bits)