BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07327 (375 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1HSO-A nrPDB 761 0.0 1HSZ-A nrPDB 720 0.0 1U3W-A nrPDB 712 0.0 1EE2-A nrPDB 665 0.0 1D1T-A nrPDB 545 e-155 1MC5-A nrPDB 478 e-135 3COS-A nrPDB 461 e-130 1P0F-A nrPDB 443 e-125 1CDO-A nrPDB 424 e-119 1E3E-A nrPDB 414 e-116 4DLA-A nrPDB 400 e-112 4JJI-A nrPDB 393 e-110 4RQU-A nrPDB 383 e-107 5TNX-A nrPDB 205 2e-53 1F8F-A nrPDB 190 8e-49 3PII-A nrPDB 130 1e-30 5YLN-A nrPDB 120 9e-28 4CPD-A nrPDB 116 1e-26 4Z6K-A nrPDB 115 2e-26 3MEQ-A nrPDB 114 5e-26 2DFV-A nrPDB 108 4e-24 5VM2-A nrPDB 107 1e-23 3S2F-A nrPDB 103 8e-23 4EEZ-A nrPDB 103 8e-23 1LLU-A nrPDB 103 2e-22 2DQ4-A nrPDB 102 2e-22 3GFB-A nrPDB 100 1e-21 3QE3-A nrPDB 97 8e-21 1PL8-A nrPDB 97 8e-21 1H2B-A nrPDB 97 9e-21 2EER-A nrPDB 95 4e-20 6N7L-A nrPDB 94 8e-20 6FG0-A nrPDB 94 8e-20 4EJ6-A nrPDB 94 1e-19 4GKV-A nrPDB 90 2e-18 5K1S-A nrPDB 89 3e-18 4UEJ-A nrPDB 89 3e-18 5KIA-A nrPDB 88 5e-18 4ILK-A nrPDB 88 6e-18 2H6E-A nrPDB 88 7e-18 1YKF-A nrPDB 86 3e-17 3TWO-A nrPDB 86 4e-17 5ENV-A nrPDB 85 5e-17 3FPL-A nrPDB 85 5e-17 1R37-A nrPDB 84 8e-17 4OH1-A nrPDB 84 1e-16 4JLW-A nrPDB 81 7e-16 5YAT-A nrPDB 75 3e-14 3IP1-A nrPDB 74 1e-13 1KOL-A nrPDB 73 2e-13 3FSR-A nrPDB 72 4e-13 1KEV-A nrPDB 72 4e-13 3FPC-A nrPDB 71 7e-13 5H82-A nrPDB 70 1e-12 1E3J-A nrPDB 70 1e-12 2DPH-A nrPDB 70 1e-12 1UUF-A nrPDB 68 7e-12 3WLE-A nrPDB 68 7e-12 4OAQ-A nrPDB 66 2e-11 5VKT-A nrPDB 65 6e-11 5Z0C-A nrPDB 62 3e-10 2OUI-A nrPDB 62 3e-10 3M6I-A nrPDB 62 4e-10 5FI5-A nrPDB 61 8e-10 6DKH-A nrPDB 59 2e-09 3UOG-A nrPDB 59 4e-09 2VCY-A nrPDB 57 1e-08 1WLY-A nrPDB 56 3e-08 1YQX-A nrPDB 55 4e-08 1QOR-A nrPDB 53 3e-07 2CDC-A nrPDB 52 5e-07 3QWB-A nrPDB 52 6e-07 1YB5-A nrPDB 51 9e-07 1Q1N-A nrPDB 50 1e-06 3SLK-A nrPDB 49 4e-06 3WID-A nrPDB 48 9e-06 5H83-A nrPDB 47 1e-05 3JYN-A nrPDB 47 1e-05 3B70-A nrPDB 47 2e-05 3FBG-A nrPDB 43 3e-04 4A27-A nrPDB 41 7e-04 4RVS-A nrPDB 40 0.001 4Y1B-A nrPDB 40 0.002 4DVJ-A nrPDB 39 0.005 2WEK-A nrPDB 38 0.006 6C49-A nrPDB 38 0.009 3HZZ-A nrPDB 37 0.014 4IDE-A nrPDB 36 0.023 3TQH-A nrPDB 35 0.040 5A3V-A nrPDB 35 0.047 2VWH-A nrPDB 34 0.087 2OBY-A nrPDB 34 0.099 4J6F-A nrPDB 33 0.21 6HRH-B nrPDB 30 1.3 4KPA-A nrPDB 30 1.4 2CF5-A nrPDB 30 1.5 6ACF-A nrPDB 30 2.1 2B25-A nrPDB 28 5.0 1V9L-A nrPDB 28 5.1 5ILO-A nrPDB 28 6.0 2VN8-A nrPDB 28 6.9 1V3V-A nrPDB 28 7.7 4A10-A nrPDB 28 9.1 >1HSO-A nrPDB Length = 374 Score = 761 bits (1966), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 120 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTILMF 375 LLHSGKSIRTILMF Sbjct: 361 LLHSGKSIRTILMF 374 >1HSZ-A nrPDB Length = 374 Score = 720 bits (1858), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/374 (93%), Positives = 362/374 (96%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVAVGIC TDDHVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCR+CKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTCR KPIHHFLG STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSA+MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 300 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLLTGRTWKGA+ GGFKSKE +PKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTILMF 375 LLHSGKSIRT+L F Sbjct: 361 LLHSGKSIRTVLTF 374 >1U3W-A nrPDB Length = 374 Score = 712 bits (1837), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/374 (92%), Positives = 359/374 (95%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVA GIC +D+HVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCRICKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTC KPIHHF+G+STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS +MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIG+LDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLLTGRTWKGAI GGFKSKE VPKLVADFMAKKFSLDALIT+VLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTILMF 375 LL SGKSIRT+L F Sbjct: 361 LLRSGKSIRTVLTF 374 >1EE2-A nrPDB Length = 373 Score = 665 bits (1716), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/374 (87%), Positives = 346/374 (92%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWE KKPFSIEEVEVAPPKAHEVRIKMVA GIC +DDHVVSGT+V P Sbjct: 1 STAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVI GHEAAGIVES+GEGVTTV+PGDKVIPL IPQCGKC +CK+PE N CLKN +S P+ Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKN-LSMPR 119 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GT+QDGTSRFTCR KPIHHFLG STFSQYTVVDE +VAKIDAASPLEKVCL+GCGFSTGY Sbjct: 120 GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY 179 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVT GSTCAVFGLGGVGLS IMGCKAAGAARII VDINKDKFAKAKE+GATEC Sbjct: 180 GSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 +NPQDYKKPIQEVL EM++GGVDFSFEVIGRLDTM+A+L CC EA G SVIVGVPPDSQN Sbjct: 240 VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQN 299 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSMNPMLLL+GRTWKGAI GGFKSK+ VPKLVADFMAKKF+LD LITHVLPFEKINEGFD Sbjct: 300 LSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD 359 Query: 362 LLHSGKSIRTILMF 375 LL SGKSIRTIL F Sbjct: 360 LLRSGKSIRTILTF 373 >1D1T-A nrPDB Length = 373 Score = 545 bits (1404), Expect = e-155, Method: Compositional matrix adjust. Identities = 257/373 (68%), Positives = 312/373 (83%), Gaps = 1/373 (0%) Query: 3 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL 62 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GIC TDDHV+ GTMV+ Sbjct: 2 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQG 122 PVI+GHEA GIVES+GEGVTTVKPGDKVIPL +PQC +C C+NP+ N C+++D++ +G Sbjct: 62 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 120 Query: 123 TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 L DGT+RFTC+ KP+HHFL STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 121 VLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 180 Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AV KV PGSTC VFGLGGVGLS IMGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 181 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 240 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ L Sbjct: 241 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 300 Query: 303 SMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 + +PMLL TGRTWKG + GG KS++ VPKLV +F+AKKF LD LITHVLPF+KI+EGF+L Sbjct: 301 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 360 Query: 363 LHSGKSIRTILMF 375 L+SG+SIRT+L F Sbjct: 361 LNSGQSIRTVLTF 373 >1MC5-A nrPDB Length = 374 Score = 478 bits (1230), Expect = e-135, Method: Compositional matrix adjust. Identities = 238/373 (63%), Positives = 291/373 (78%), Gaps = 5/373 (1%) Query: 4 AGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP-- 61 A +VIKCKAAV WE KP SIEE+EVAPPKAHEVRIK++A +C TD + +SG P Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGA--DPEG 59 Query: 62 -LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 PVILGHE AGIVESVGEGVT +K GD VIPL IPQCG+C+ C NP++N C K V+ Sbjct: 60 CFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQG 119 Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 +G + DGTSRFTC+ K I H++G STFS+YTVV + +VAKID +PL+KVCL+GCG STG Sbjct: 120 KGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTG 179 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 YG+AVN AK+ PGS CAVFGLGGVGL+ IMGCK AGA+RII VDINKDKFA+AKE GATE Sbjct: 180 YGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATE 239 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 CINPQD+ KPIQEVL EMTDGGVD+SFE IG + M A+L CH+ G SV+VGV + Sbjct: 240 CINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGE 299 Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 ++ P L+TGRTWKG GG+KS E VPKLV+++M+KK +D +TH L F++IN+ F Sbjct: 300 EIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAF 359 Query: 361 DLLHSGKSIRTIL 373 +L+HSGKSIRT++ Sbjct: 360 ELMHSGKSIRTVV 372 >3COS-A nrPDB Length = 381 Score = 461 bits (1187), Expect = e-130, Method: Compositional matrix adjust. Identities = 230/381 (60%), Positives = 285/381 (74%), Gaps = 7/381 (1%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV- 59 M T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C TD V+ Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 60 TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYC-----LK 114 PVI+GHEAAGIVES+G GVT VKPGDKVIPL P C KC+ C +P +N C LK Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 115 NDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIG 174 + S+ Q ++D TSRFTC+ KP++HF G STFSQYTVV + +AKID + LE+VCL+G Sbjct: 122 SPASDQQ-LMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLG 180 Query: 175 CGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK 234 CGFSTGYG+A+N AKVTPGSTCAVFGLGGVGLSA+MGCKAAGA+RII +DIN +KF KAK Sbjct: 181 CGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK 240 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 LGAT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +G Sbjct: 241 ALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIG 300 Query: 295 VPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFE 354 V S+ L++ P L+ GRT G GG+KS + +PKLV D+ KKF+LDAL+TH LPF+ Sbjct: 301 VAAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFD 360 Query: 355 KINEGFDLLHSGKSIRTILMF 375 KI+E FDL++ GKSIRTIL+F Sbjct: 361 KISEAFDLMNQGKSIRTILIF 381 >1P0F-A nrPDB Length = 373 Score = 443 bits (1139), Expect = e-125, Method: Compositional matrix adjust. Identities = 222/375 (59%), Positives = 289/375 (77%), Gaps = 2/375 (0%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60 M TAGK I CKAAV WE KP S+E + VAPPKAHEVRIK++A GICG+D V+ + + Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 PVILGHEA G+VES+G GVT VKPGDKVIPL +PQCG CR CK+ SN+C KND+ Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + D TSRFTCR KPI++ +G STF++YTVV + AVAKID +PLE CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 YG+AVN AKVTPGSTCAVFGLGGVG SAI+GCKAAGA+RII V +KDKF KA ELGATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 C+NP+DY KPI EV+ E T+GGVD++ E GR++TMM +L + G +V++G+ ++ Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 L ++P+LLLTGR+ KG++ GGFK +E V +LV D+M KK +++ L++ L ++IN+ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKGEE-VSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 361 DLLHSGKSIRTILMF 375 +LL SG+ +R+I+++ Sbjct: 359 ELLSSGQGVRSIMIY 373 >1CDO-A nrPDB Length = 374 Score = 424 bits (1089), Expect = e-119, Method: Compositional matrix adjust. Identities = 206/373 (55%), Positives = 269/373 (72%), Gaps = 2/373 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTD-DHVVSGTMVT 60 +T GKVIKCKAAV WE KP IEE+EV P A+E+RIK++A G+C TD H+ G Sbjct: 1 ATVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 PV+LGHE AGIVESVG GVT +PG+KVIPL I QCG+CR C++P++N C+K + Sbjct: 61 GFPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANES 120 Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 + +RFTC+ + + FLG STFSQYTVV++ AVAKID ++PL+ VCL+GCG STG Sbjct: 121 PDVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTG 180 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 +G+AVN AKV PGSTCAVFGLG VGL+A+MGC +AGA RIIAVD+N DKF KAK GAT+ Sbjct: 181 FGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATD 240 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 +NP D+ +PI +VL +MT+GGVDFS E +G + M +L C + G SV+VG D Sbjct: 241 FVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGW-TDLH 299 Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 +++ P+ L+ GRTWKG++ GGFK K+ VPK+V ++ KK LD ITH +P E +N+ Sbjct: 300 DVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAI 359 Query: 361 DLLHSGKSIRTIL 373 DL+ GK IRT+L Sbjct: 360 DLMKHGKCIRTVL 372 >1E3E-A nrPDB Length = 376 Score = 414 bits (1065), Expect = e-116, Method: Compositional matrix adjust. Identities = 206/377 (54%), Positives = 268/377 (71%), Gaps = 6/377 (1%) Query: 3 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL 62 T GKVIKCKAA+ W+ P IEE+EV+PPKA EVRI+++A +C TD + Sbjct: 2 TQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKALF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLK-NDVSNP- 120 PV+LGHE AGIVESVG GVT KPGDKVIP PQC +C++C +P +N C K + P Sbjct: 62 PVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPT 121 Query: 121 --QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFS 178 Q ++D TSRFTC+ + I+HF+G+S+FSQYTVV E +A++D + LE+VCLIGCGFS Sbjct: 122 IDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFS 181 Query: 179 TGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGA 238 +GYG+A+N AKVTPGSTCAVFGLG VGLSAI+GCK AGA+RIIA+DIN +KF KAK LGA Sbjct: 182 SGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGA 241 Query: 239 TECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298 T+C+NP++ KP+Q+V+ E+T GGVD+S + G T+ A++ C G+ +VG D Sbjct: 242 TDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKVD 301 Query: 299 SQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINE 358 + ++L GR+ G GG+KS + VP LV+D+ KKF LD L+TH LPFE IN+ Sbjct: 302 EMTIPTVDVIL--GRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIND 359 Query: 359 GFDLLHSGKSIRTILMF 375 DL+ GKSIRTIL F Sbjct: 360 AIDLMKEGKSIRTILTF 376 >4DLA-A nrPDB Length = 396 Score = 400 bits (1028), Expect = e-112, Method: Compositional matrix adjust. Identities = 201/377 (53%), Positives = 260/377 (68%), Gaps = 3/377 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 +T G+VI CKAAV WE KP IE+V+VAPP+A EVR+K++ +C TD + SG Sbjct: 19 ATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEG 78 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 L P +LGHEAAGIVESVGEGVT V+PGD VIP +C +C+ CK+ ++N C K + Sbjct: 79 LFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATG 138 Query: 121 QGTL-QDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D SRF+ KPI+HF+G STFSQYTVV + +VAKID +PLEKVCL+GCG T Sbjct: 139 VGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPT 198 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS AVFGLG VGL+ G KAAGA+RII +DI+ KF +AK G T Sbjct: 199 GLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVT 258 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E INP+++++PIQ+V+ ++TDGGVD+SFE IG + M ++L CCH+ GTSVIVGV Sbjct: 259 EFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASG 318 Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG GGFKS+ VP LV ++ K+ +D ITH + IN+ Sbjct: 319 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKA 378 Query: 360 FDLLHSGKSIRTIL-MF 375 FDL+H G +R +L MF Sbjct: 379 FDLMHDGDCLRVVLDMF 395 >4JJI-A nrPDB Length = 378 Score = 393 bits (1009), Expect = e-110, Method: Compositional matrix adjust. Identities = 200/374 (53%), Positives = 255/374 (68%), Gaps = 2/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 +T G+VI CKAAV +E KP IE+V+VAPP+A EVRIK++ +C TD + SG Sbjct: 1 ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEG 60 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 L P ILGHEAAGIVESVGEGVT V+ GD VIP +C +C+ CK+ ++N C K + Sbjct: 61 LFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATG 120 Query: 121 QG-TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D SRF+ KPI+HF+G STFSQYTVV + +VAKID +PL+KVCL+GCG T Sbjct: 121 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 180 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS A+FGLG VGL+ G K AGA+RII +DI+ K+ AK+ G Sbjct: 181 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 240 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E +NP+D+ KPIQEV+ ++TDGGVD+SFE IG + M A+L CCH+ GTSVIVGV Sbjct: 241 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 300 Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG GGFKS+ VP LV +M K+ +D ITH L +IN+ Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 360 Query: 360 FDLLHSGKSIRTIL 373 FDLLH G +R +L Sbjct: 361 FDLLHEGTCLRCVL 374 >4RQU-A nrPDB Length = 375 Score = 383 bits (984), Expect = e-107, Method: Compositional matrix adjust. Identities = 187/370 (50%), Positives = 246/370 (66%), Gaps = 2/370 (0%) Query: 6 KVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL-PV 64 ++I+CKAAV WE KP IEEVEVAPP+ HEVRIK++ +C TD + TPL P Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQG-T 123 I GHEA GIVESVGEGVT ++PGD V+P+ +CG+CR C + ESN C ++ +G Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 124 LQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + DG SRF+ KPI+HFLG STFS+YTVV VAKI+ +PL+KVC++ CG STG G+ Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 +NVAK G + A+FGLG VGL A G + AGA+RII VD N +F +AKE G TEC+N Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 P+D+ KPIQ+V+ EMTDGGVD S E G + M+ + C H+ G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 304 MNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 +PM L RT KG G +K K +P +V +M K+ L+ ITH +PF +IN+ FD + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 364 HSGKSIRTIL 373 G+SIR I+ Sbjct: 362 LKGESIRCII 371 >5TNX-A nrPDB Length = 383 Score = 205 bits (522), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 130/356 (36%), Positives = 188/356 (52%), Gaps = 8/356 (2%) Query: 21 PFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEG 80 PFSIE + P+ EV +++VA G+C TD V PLP +LGHE AG+VE+VG Sbjct: 29 PFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVGPN 88 Query: 81 VTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG-TSRFTCRRKPIH 139 V T+ GD V+ L CG C C YC + N G DG T+ +P+H Sbjct: 89 VKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEPLH 147 Query: 140 -HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAV 198 HF S+F+ Y + EN K+ +PLE + +GCG TG G+ +N V GS+ A Sbjct: 148 DHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSFAS 207 Query: 199 FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 FG G VG+SA+M + AGA IIAVDI + A A ELGAT IN ++ + + ++E+ Sbjct: 208 FGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIREI 265 Query: 259 TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN-PMLLLTGRTWKG 317 T GGVD++ E G L +++ + + GT +VG P + LLL G T +G Sbjct: 266 TGGGVDYALESTG-LPAVLSQGIDALGSRGTMGVVGAPKLGTKAEFDVNSLLLGGHTIRG 324 Query: 318 AILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTIL 373 + G + +P+LV + +F D L+ P E+IN+ SG +++ IL Sbjct: 325 IVEGDSVPQTFIPQLVQLHLQGRFPFDRLVK-FYPLEQINQAAADSSSGITLKPIL 379 >1F8F-A nrPDB Length = 371 Score = 190 bits (483), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 121/356 (33%), Positives = 187/356 (52%), Gaps = 10/356 (2%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGV 81 F ++ +++ P+ EV +K+VA G+C TD V PLP +LGHE +GI+E++G V Sbjct: 19 FELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGSGIIEAIGPNV 78 Query: 82 TTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPI--H 139 T ++ GD V+ L+ CGKC C YC + N G +G + + Sbjct: 79 TELQVGDHVV-LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHALCTHDQGVVND 137 Query: 140 HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF 199 HF S+F+ Y + EN K+ P+E + +GCG TG G+ +N KVTP S+ + Sbjct: 138 HFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALKVTPASSFVTW 197 Query: 200 GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G G VGLSA++ K GA+ IIAVDI + + AK+LGAT IN + + P+ + KE+T Sbjct: 198 GAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKT-QDPVAAI-KEIT 255 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--DSQNLSMNPMLLLTGRTWKG 317 DGGV+F+ E G + + + G +VG P + +N LLL G+T G Sbjct: 256 DGGVNFALESTGSPEILKQGVDALG-ILGKIAVVGAPQLGTTAQFDVND-LLLGGKTILG 313 Query: 318 AILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTIL 373 + G K+ +P+LV + KF D L+ F++IN+ G +++ I+ Sbjct: 314 VVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQAAIDSRKGITLKPII 368 >3PII-A nrPDB Length = 339 Score = 130 bits (327), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 120/360 (33%), Positives = 165/360 (45%), Gaps = 37/360 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTP-LPVILGH 68 KAAV+ + K+P I+EVE EV +++ A G+C TD H G V P LP+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E GIVE VG GVT +K GD+V IP CG C +YCL Q TL Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHC--------DYCLSG-----QETL--- 105 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 C + + +++Y + V KI E+ I C T Y A+ V Sbjct: 106 -----CEHQKNAGYSVDGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-KALKV 159 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A++G+GG G A+ KA G ++AVDI +K AKELGA +NP Sbjct: 160 TGAKPGEWVAIYGIGGFGHVAVQYAKAMG-LNVVAVDIGDEKLELAKELGADLVVNP--L 216 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 K+ + +KE GGV + V S G V+VG+PP+ + + Sbjct: 217 KEDAAKFMKEKV-GGVHAAV-VTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFDT 274 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G G+I+G K + + A+ K I V P EKINE FD + G+ Sbjct: 275 -VLNGIKIIGSIVGTRKDLQEALQFAAEGKVKT------IIEVQPLEKINEVFDRMLKGQ 327 >5YLN-A nrPDB Length = 356 Score = 120 bits (301), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 105/353 (29%), Positives = 161/353 (45%), Gaps = 37/353 (10%) Query: 20 KPFSIEEVEVAPP---KAHEVRIKMVAVGICGTDDHVVSGTMVT-PLPVILGHEAAGIVE 75 KP V+V P K + +++V ICGTD H++ G + T ILGHE GIVE Sbjct: 12 KPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEGIGIVE 71 Query: 76 SVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRR 135 VGEGV+ K GDKV+ + CGKC CK +C +++ G L DG R Sbjct: 72 EVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHC-EDEGGWIFGHLIDGMQAEYLR- 129 Query: 136 KPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGST 195 + H + + DE V D TGY V KV PG + Sbjct: 130 --VPHADNTLYHTPEDLSDEALVMLSDI-------------LPTGYEIGVLKGKVEPGCS 174 Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 A+ G G VGL+A++ + A++I VD++ ++ A GAT +N D +K I+E+ Sbjct: 175 VAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEKAIKEIY 234 Query: 256 KEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN--PMLLLTG 312 ++TDG GVD + E +G + A+ C + I+GV N ++ P+ Sbjct: 235 -DLTDGRGVDVAIEAVG----IPATFDFCQK------IIGVDGTVANCGVHGKPVEFDLD 283 Query: 313 RTWKGAI--LGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 + W I G S P+L+ + K + L+TH +I + +++ Sbjct: 284 KLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVF 336 >4CPD-A nrPDB Length = 347 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 105/369 (28%), Positives = 167/369 (45%), Gaps = 34/369 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAH--EVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEA 70 AV++E K+ +++EV AP H + +++ GICG+D H+ G + +LGHE Sbjct: 3 AVVFENKERVAVKEVN-APRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVLGHEF 61 Query: 71 AGIVESVGEGVTTVKPGDKVI-PLAIPQCGKCRICKNPESNYCLKNDVSN--PQ-GTLQD 126 G VE+VGEG+ ++PGD V+ P I CG C C+ + N C + V P G LQ Sbjct: 62 VGQVEAVGEGIQDLQPGDWVVGPFHI-ACGTCPYCRRHQYNLCERGGVYGYGPMFGNLQG 120 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 + R P FS + K+ E+ G ST YG + Sbjct: 121 AQAEIL--RVP---------FSNVNL------RKLPPNLSPERAIFAGDILSTAYGGLIQ 163 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 ++ PG + AV G G VGL AI + GA++I+A+D ++ +A LGA IN + Sbjct: 164 -GQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INAEQ 221 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 + P++ V E D G D E +G T+ +L G VGV N P Sbjct: 222 -ENPVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPG-GRVSAVGV----DNAPSFP 275 Query: 307 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAK-KFSLDALITHVLPFEKINEGFDLLHS 365 L +G G + V +A + + +++H LP E+ G++L Sbjct: 276 FPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDR 335 Query: 366 GKSIRTILM 374 ++++ +L+ Sbjct: 336 KEALKVLLV 344 >4Z6K-A nrPDB Length = 346 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 110/361 (30%), Positives = 164/361 (45%), Gaps = 39/361 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTPL-PVILGH 68 KAAVL E + IEEV++ P A E+ +KM A G+C TD H V G V P P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E G++ +VGEGVT VK GD+V + CG C +CL G Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHC--------THCL-------------G 100 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 C + + +F++Y + + N V I + ++ + C T Y + + Sbjct: 101 GWETLCESQQNSGYSVNGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKM 159 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G A+ A G + AVDI+ DK A AK+LGA +N ++ Sbjct: 160 TDTKPGDWVVISGIGGLGHMAVQYAIAMG-LNVAAVDIDDDKLAFAKKLGAKVTVNAKN- 217 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 P + + KE+ V + S+L GT V G+PP +S+ Sbjct: 218 TDPAEYLQKEIGGAHGALVTAVSAKAFDQALSML---RRGGTLVCNGLPPGDFPVSIFDT 274 Query: 308 LLLTGRTWKGAILGG-FKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 +L G T +G+I+G +E + MA + A +T P E IN+ F+ + G Sbjct: 275 -VLNGITIRGSIVGTRLDLQESLD------MAAAGKVKATVT-AEPLENINDIFERMRQG 326 Query: 367 K 367 K Sbjct: 327 K 327 >3MEQ-A nrPDB Length = 365 Score = 114 bits (286), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 110/367 (29%), Positives = 151/367 (41%), Gaps = 35/367 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTP-LPVILGH 68 KAAV+ KP +I+EV + P ++++ + A G+C TD H G V P P I GH Sbjct: 27 KAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGH 86 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E G V +VG GV VK GD+V IP CG CR C C + L G Sbjct: 87 EGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQ--------LNTG 138 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 S F++Y V D N V + ++ + C T Y + V Sbjct: 139 YSVN-------------GGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGLKV 184 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G A+ +A G + AVDI+ K A+ LGAT +N + Sbjct: 185 TDTKPGDWVVISGIGGLGHMAVQYARAMG-LNVAAVDIDDRKLDLARRLGATVTVNAKTV 243 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 P + KE TDGG V L GT + G+PP LS+ M Sbjct: 244 ADPAAYIRKE-TDGGAQGVL-VTAVSPKAFEQALGMVARGGTVSLNGLPPGDFPLSIFNM 301 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G T +G+I+G + AD K E IN FD + G Sbjct: 302 -VLNGVTVRGSIVGTRLDLQESLDFAADGKVKA------TIQTGKLEDINAIFDDMRQGN 354 Query: 368 SIRTILM 374 I+M Sbjct: 355 IEGRIVM 361 >2DFV-A nrPDB Length = 347 Score = 108 bits (270), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 101/359 (28%), Positives = 160/359 (44%), Gaps = 41/359 (11%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVV-----SGTMVTPLPVILGHEAAGIVESVGEG 80 EV+V P EV IK++A ICGTD H+ + + + P P I+GHE AG V +G G Sbjct: 20 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP-PQIMGHEVAGEVVEIGPG 78 Query: 81 VTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHH 140 V ++ GD V CGKC C+ + + C + G DG Sbjct: 79 VEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIF---GVDTDG------------- 122 Query: 141 FLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP--GSTCAV 198 F++Y VV + K + P E L G+AV+ P G + + Sbjct: 123 -----VFAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNAVDTVLAGPISGKSVLI 172 Query: 199 FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G G +GL I KA+GA +I + + + AK++GA INP +++ + + + ++ Sbjct: 173 TGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINP--FEEDVVKEVMDI 230 Query: 259 TDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKG 317 TDG GVD E G + L A G ++G+ P + N +++ T G Sbjct: 231 TDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGKVTIDFNNLIIFKALTIYG 289 Query: 318 AILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSGKSIRTILMF 375 + G E + + K +LD +ITH F+K E F+L+ +GK+ + + M Sbjct: 290 --ITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFML 346 >5VM2-A nrPDB Length = 347 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 96/355 (27%), Positives = 149/355 (41%), Gaps = 40/355 (11%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDH-VVSGTMVTP----LPVILGHE 69 + ++ I E+ PK EV IK+ VGICG+D H SG + P + LGHE Sbjct: 7 ILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHE 66 Query: 70 AAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGT 128 AG V +VG V KPGD+V I +P CG CR C + N C D Q + Sbjct: 67 CAGTVVAVGSRVRKFKPGDRVNIEPGVP-CGHCRYCLEGKYNICPDVDFMATQPNYRGAL 125 Query: 129 SRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 + + C + + L + + + E A + AA +A Sbjct: 126 THYLCHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAM---------------------LA 164 Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN--PQD 246 V PG + G G +GL + CK GA I VD+ + + A A++LGAT IN +D Sbjct: 165 DVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKED 224 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 Q+ ++M G D FE G T+ + G +IVG P + ++ Sbjct: 225 TIARCQQFTEDM---GADIVFETAGSAVTVKQAPYLVMRG-GKIMIVGTVPGASAIN--- 277 Query: 307 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 L R I F+ P + + +F + +++TH+ + + + F+ Sbjct: 278 -FLKINREV--TIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >3S2F-A nrPDB Length = 340 Score = 103 bits (258), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 108/369 (29%), Positives = 156/369 (42%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTP-LPVILGH 68 KAAV+ P +I+EV V P +V++K+ A G+C TD H G V P LP I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E G V +VG GV+ VK GD+V +P CG C C C K N ++ G Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQ--QNTGYSVNGG 121 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + +Y V D N V + ++ I C T Y + V Sbjct: 122 -------------------YGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKV 161 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G A+ +A G R+ AVDI+ K A+ LGA +N +D Sbjct: 162 TDTRPGQWVVISGIGGLGHVAVQYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVNARD- 219 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 P + KE+ G V + + GT + G+PP + Sbjct: 220 TDPAAWLQKEI---GGAHGVLVTAVSPKAFSQAIGMVRRGGTIALNGLPPGDFGTPIFD- 275 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 ++L G T +G+I+G + L DF A + T L + +N+ F L GK Sbjct: 276 VVLKGITIRGSIVG--TRSDLQESL--DFAAHGDVKATVSTAKL--DDVNDVFGRLREGK 329 Query: 368 -SIRTILMF 375 R +L F Sbjct: 330 VEGRVVLDF 338 >4EEZ-A nrPDB Length = 348 Score = 103 bits (258), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 108/368 (29%), Positives = 166/368 (45%), Gaps = 51/368 (13%) Query: 11 KAAVLWELKKPFS-IEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHE 69 KAAV+ ++ + E E+ K +E + M G+C TD HV +G +LGHE Sbjct: 2 KAAVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHE 61 Query: 70 AAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGT 128 GIV+ +G V++++ GD+V + CG C C + +C +V N ++ G Sbjct: 62 GIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFC--REVKNAGYSVDGGM 119 Query: 129 SRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 + + VV + AV D P+E I C T Y A+ V+ Sbjct: 120 AE------------------EAIVVADYAVKVPDGLDPIE-ASSITCAGVTTY-KAIKVS 159 Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 V PG +FG GG+G AI K A++IAVDIN+DK AK++GA IN D Sbjct: 160 GVKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDV- 218 Query: 249 KPIQEVLKEMTDG-GVDFSFE-VIGRL--DTMMASLLCCHEACGTSVIVGVPPDSQNLSM 304 P+ E+ K++T G GV + + R+ + +ASL + G V V VP LS+ Sbjct: 219 NPVDEI-KKITGGLGVQSAIVCAVARIAFEQAVASL----KPMGKMVAVAVPNTEMTLSV 273 Query: 305 NPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDAL-----ITHVLPFEKINEG 359 P ++ G G+++G +A+ F A I E+IN+ Sbjct: 274 -PTVVFDGVEVAGSLVGTRLD-----------LAEAFQFGAEGKVKPIVATRKLEEINDI 321 Query: 360 FDLLHSGK 367 D + +GK Sbjct: 322 IDEMKAGK 329 >1LLU-A nrPDB Length = 342 Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 84/290 (28%), Positives = 127/290 (43%), Gaps = 30/290 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT--PLPVILGH 68 KAAV+ P IEEV+V P +V +K+ A G+C TD H G PLP I GH Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGH 67 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E G V +VG GVT VK GD+V IP CG C C C N ++ G Sbjct: 68 EGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQ--QNTGYSVNGG 125 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 +++Y + D N V + ++ I C T Y + Sbjct: 126 -------------------YAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-KGLKQ 165 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A+ G+GG+G A+ +A G + A+DI+ K A++LGA+ +N + Sbjct: 166 TNARPGQWVAISGIGGLGHVAVQYARAMG-LHVAAIDIDDAKLELARKLGASLTVNARQ- 223 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 + P++ + +++ G V ++ + GT +VG+PP Sbjct: 224 EDPVEAIQRDI---GGAHGVLVTAVSNSAFGQAIGMARRGGTIALVGLPP 270 >2DQ4-A nrPDB Length = 343 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 100/357 (28%), Positives = 158/357 (44%), Gaps = 49/357 (13%) Query: 29 VAPPKAHEVRIKMVAVGICGTDDHVVSGT-----MVTPLPVILGHEAAGIVESVGEGVTT 83 V P E+ +++ A ICGTD H+ + P P++ GHE +G+VE+VG GV Sbjct: 20 VPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRP-PLVTGHEFSGVVEAVGPGVRR 78 Query: 84 VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143 + GD V + C C C+ + CL + G +DG Sbjct: 79 PQVGDHVSLESHIVCHACPACRTGNYHVCLNTQI---LGVDRDG---------------- 119 Query: 144 ISTFSQYTVVD-ENAVAK-----IDAASPLEKVCLIGCGFSTGY-GSAVNVAKVTPGSTC 196 F++Y VV ENA + A+ LE G T Y GS V+ G + Sbjct: 120 --GFAEYVVVPAENAWVNPKDLPFEVAAILEP---FGNAVHTVYAGSGVS------GKSV 168 Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 + G G +GL A M +A+GA I+ D N + A A+ A +NP ++ + EV++ Sbjct: 169 LITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNP--LEEDLLEVVR 225 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWK 316 +T GV+ E G + L+ G + I+G+P D + L++ G T Sbjct: 226 RVTGSGVEVLLEFSGNEAAIHQGLMALIPG-GEARILGIPSDPIRFDLAGELVMRGITAF 284 Query: 317 GAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTIL 373 G + G + + + A + + L L+TH LP + E F LL SG++++ IL Sbjct: 285 G--IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASGQAVKVIL 339 >3GFB-A nrPDB Length = 350 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 98/358 (27%), Positives = 157/358 (43%), Gaps = 41/358 (11%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVV-----SGTMVTPLPVILGHEAAGIVESVGEG 80 EV+V P EV IK++A ICGTD H+ + + + P P I+GHE AG V VG G Sbjct: 21 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP-PQIMGHEVAGEVVEVGPG 79 Query: 81 VTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHH 140 V ++ GD + CGKC CK+ + C + G DG Sbjct: 80 VEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIF---GVDMDG------------- 123 Query: 141 FLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP--GSTCAV 198 F+ Y +V K P E L G+AV+ P G + + Sbjct: 124 -----VFAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGNAVDTVLAGPIAGRSTLI 173 Query: 199 FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G G +GL I KA+GA +I + ++ + AK++GA +NP + + P++ V+ ++ Sbjct: 174 TGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFE-EDPVKFVM-DI 231 Query: 259 TDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKG 317 TDG GV+ E G + L G ++G+ P + N +++ G Sbjct: 232 TDGAGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLFPREVTIDFNNLIIFKALEVHG 290 Query: 318 AILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSGKSIRTILM 374 + G E + + + K +LD +ITH F+K E F+L+ +GK+ + + Sbjct: 291 --ITGRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTGKVVFF 346 >3QE3-A nrPDB Length = 355 Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 98/361 (27%), Positives = 159/361 (44%), Gaps = 41/361 (11%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESV 77 +E + P +EV +KM +VGICG+D H G V P++LGHEA+G V V Sbjct: 18 LRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKV 77 Query: 78 GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP 137 G V ++PGD+V AI Q G R + D G + F C P Sbjct: 78 GSLVRHLQPGDRV---AI-QPGAPR-----------QTDEFCKIGRYNLSPTIFFCATPP 122 Query: 138 IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 ++ + N K+ E+ LI S G A A VT G+ Sbjct: 123 DD-----GNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGI-HACRRAGVTLGNKVL 175 Query: 198 VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-----NPQDYKKPIQ 252 V G G +GL ++ KA GAA+++ D++ + +KAKE+GA + +P++ K ++ Sbjct: 176 VCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVE 235 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTG 312 +L + + E G ++ A + H GT V+VG+ + M + L+ Sbjct: 236 GLLGSKP----EVTIECTGVETSIQAGIYATHSG-GTLVLVGLGSE-----MTSVPLVHA 285 Query: 313 RTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTI 372 T + I G F+ P ++ +K ++ L+TH P EK E F+ G ++ + Sbjct: 286 ATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVM 345 Query: 373 L 373 + Sbjct: 346 I 346 >1PL8-A nrPDB Length = 356 Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 98/364 (26%), Positives = 157/364 (43%), Gaps = 47/364 (12%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESV 77 +E + P +EV ++M +VGICG+D H G + P++LGHEA+G VE V Sbjct: 19 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 78 Query: 78 GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP 137 G V +KPGD+V AI E +ND G S F C P Sbjct: 79 GSSVKHLKPGDRV---AI------------EPGAPRENDEFCKMGRYNLSPSIFFCATPP 123 Query: 138 ----IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 193 + F + Y + D + PL S G A VT G Sbjct: 124 DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLG 172 Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ QE Sbjct: 173 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQE 230 Query: 254 VLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL 309 + +++ +G + + + E G ++ A + GT V+VG+ + M + L Sbjct: 231 IARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GTLVLVGLGSE-----MTTVPL 283 Query: 310 LTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSI 369 L + I G F+ P ++ +K ++ L+TH P EK E F+ G + Sbjct: 284 LHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 343 Query: 370 RTIL 373 + +L Sbjct: 344 KIML 347 >1H2B-A nrPDB Length = 359 Score = 97.4 bits (241), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 79/276 (28%), Positives = 132/276 (47%), Gaps = 36/276 (13%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAH-EVRIKMVAVGICGTDDHVVSGT---MVTP- 61 V + KAA L E KP IE+V+ + +V +++ G+C TD H+V G ++ P Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LP LGHE G +E V EGV ++ GD VI G C C+ E +C ++ P Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHC--ENLEFPG 130 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVC----LIGCGF 177 + G F+++ +V K+ EK+ L G Sbjct: 131 LNIDGG-------------------FAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGI 171 Query: 178 STGYGSAVNVAK-VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKEL 236 T Y + A+ + PG+ A+ G+GG+G A+ K A +IA+D+ ++K A+ L Sbjct: 172 -TAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERL 230 Query: 237 GATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIG 271 GA ++ + + P+++V+ E+T G GV+ + + +G Sbjct: 231 GADHVVDAR--RDPVKQVM-ELTRGRGVNVAMDFVG 263 >2EER-A nrPDB Length = 347 Score = 95.1 bits (235), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 101/382 (26%), Positives = 161/382 (42%), Gaps = 55/382 (14%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT---------MVTP 61 +A L E+ KP +E++ + PK +V IK+ A G+C +D H+ G + Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C D Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC---DSPRWL 118 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTG 180 G DG +++Y +V + K+ S +E L G +T Sbjct: 119 GINYDG------------------AYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSGVTT- 159 Query: 181 YGSAVNVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 AV A + P T V G GG+G AI KA A II VD+ ++ AK GA Sbjct: 160 -YRAVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGAD 218 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 IN + P+ E+ + G D ++ T+ + G V+VG+ Sbjct: 219 YVINASS-QDPVSEIRRITQGKGADAVIDLNNSEKTLSIYPYVLAKQ-GKYVMVGL--FG 274 Query: 300 QNLSMN-PMLLLTGRTWKGAILGGFKSKECVPKLVADF-----MAKKFSLDALITHVLPF 353 +L + P++ L + G+++G +DF +A+ + ++T + Sbjct: 275 ADLKYHAPLITLNEVQFIGSLVGN----------QSDFLGIMSLAEAGKVKPMVTKTMKL 324 Query: 354 EKINEGFDLLHSGKSI-RTILM 374 E+ NE D L + K++ R +L+ Sbjct: 325 EEANEAIDNLENFKAVGRQVLV 346 >6N7L-A nrPDB Length = 353 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 103/368 (27%), Positives = 154/368 (41%), Gaps = 54/368 (14%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT--PLPVILGH 68 KAAV+ +P I+EV V P +EV +K++A G+C TD H V G +P+I GH Sbjct: 15 KAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGH 74 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E GIV + G VK GD V +P CG C C C + G DG Sbjct: 75 EGVGIVVACGPD-AMVKEGDAVGVPWLYSACGCCDYCITGWETLC---EAQQNGGYSVDG 130 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 F++Y + D V + + ++ I C T Y + Sbjct: 131 ------------------GFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-KGLKE 171 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 + PG A+ G+GG+G A+ KA G + A+D+ DK AK+LGA +N + Sbjct: 172 TETKPGEWVAISGIGGLGHVAVQYAKAMG-MHVAAIDVADDKLELAKKLGADLTVNAK-- 228 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL--------LCCHEACGTSVIVGVPPDS 299 TD G EV G ++ ++ + GT + G+PP S Sbjct: 229 ----------TTDPGTYLHKEVGGMHGALITAVSPIAFKQGIDVLRRKGTIALNGLPPGS 278 Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359 L + +L T +G+I+G K + DF A + + A +T E IN+ Sbjct: 279 FELPIFETVLKR-ITVRGSIVGTRKDLQ----EALDF-ANEGLVKATVTSA-KLEDINDV 331 Query: 360 FDLLHSGK 367 FD + G+ Sbjct: 332 FDKMKKGQ 339 >6FG0-A nrPDB Length = 352 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 76/273 (27%), Positives = 119/273 (43%), Gaps = 28/273 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVV---SGTMVTPLPVILG 67 KA E+ + ++ P E+ +K+ A G+C +D V+ + LP+ LG Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKN-DVS-NPQGTLQ 125 HE G V +GEGVT GD V CG C C NYC + D+ P G Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPPGYGS 121 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTGYGSA 184 G+ ++Y +VD + I P+ L G + + + Sbjct: 122 PGS------------------MAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAIS 163 Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 + + PGST V G+GG+G I +A AAR+IAVD++ D+ A A+E+GA + Sbjct: 164 RVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKS 223 Query: 245 QDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM 276 + ++E+T G G F+ +G T+ Sbjct: 224 ---GAGAADAIRELTGGQGATAVFDFVGAQSTI 253 >4EJ6-A nrPDB Length = 370 Score = 94.0 bits (232), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 97/346 (28%), Positives = 152/346 (43%), Gaps = 32/346 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAG 72 AV E S+ V + P ++ +K+ A GICGTD H++ G + PV LGHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 73 IVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 IV G V + PG ++ CG+C C+ N C +N Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLC-RN----------------- 127 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 R IH G F++Y +V +I L+ V C V+++ + Sbjct: 128 LRAIGIHRDGG---FAEYVLVPRKQAFEIPLT--LDPVHGAFCEPLACCLHGVDLSGIKA 182 Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ--DYKKP 250 GST A+ G G +GL + + AGA +I K A+E+GAT ++P D + Sbjct: 183 GSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEA 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 310 I + + GGVD E G +T+ S +A GT VI+GV P + + + P +L Sbjct: 243 IAGPVG-LVPGGVDVVIECAGVAETVKQSTRLA-KAGGTVVILGVLPQGEKVEIEPFDIL 300 Query: 311 TGRTWKGAILGGFKSKECVPKLVADFMAK-KFSLDALITHVLPFEK 355 R + +LG F + V + AD +A +D +I+ + ++ Sbjct: 301 F-RELR--VLGSFINP-FVHRRAADLVATGAIEIDRMISRRISLDE 342 >4GKV-A nrPDB Length = 336 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 90/290 (31%), Positives = 133/290 (45%), Gaps = 28/290 (9%) Query: 33 KAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-I 91 K E +KM G+C TD HV +G VILGHE G+V VG GVT++KPGD+ + Sbjct: 23 KHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASV 82 Query: 92 PLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYT 151 CG C C + C V N G DG C + Y Sbjct: 83 AWFYEGCGHCEYCNSGNETLC--RSVKNA-GYSVDGGMAEEC-----------IVVADYA 128 Query: 152 VVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMG 211 V + + A+S I C T Y AV ++K+ PG A++GLGG+G A+ Sbjct: 129 VKVPDGLDSAAASS-------ITCAGVTTY-KAVKLSKIRPGQWIAIYGLGGLGNLALQY 180 Query: 212 CKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIG 271 K A++IA+D+N ++ A E+GA IN + + ++++E T G + Sbjct: 181 AKNVFNAKVIAIDVNDEQLKLATEMGADLAINS--HTEDAAKIVQEKTGGAHAAVVTAV- 237 Query: 272 RLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILG 321 S + A G V VG+PP+S +L + P L+L G G+++G Sbjct: 238 -AKAAFNSAVDAVRAGGRVVAVGLPPESMSLDI-PRLVLDGIEVVGSLVG 285 >5K1S-A nrPDB Length = 362 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 96/348 (27%), Positives = 151/348 (43%), Gaps = 44/348 (12%) Query: 11 KAAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILG 67 KA VL + +E + + P EV +++ A G+C D G + T +P ILG Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 HEAAG V VG K GD+ L CG C +C++ ++ C K D Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLC-KTD----------- 126 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 +RF P ++Q+ V + ++ A+ P + + C T + Sbjct: 127 -NRFFGEELP-------GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTR 178 Query: 188 AKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ- 245 KV G T + G GGVGLS++ + G AR+IAV ++ K KE GA E I + Sbjct: 179 GKVRAGETVLITGASGGVGLSSVQLARLDG-ARVIAVTSSEAKVQALKEAGADEVIVSRG 237 Query: 246 -DYKKPIQEVLKEMTDGGVDFSFEVIGR--LDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 D+ +V K GVD + E++G D + S+ A G V+V +S + Sbjct: 238 LDFAS---DVRKRTQGAGVDVAVEIVGSATFDQTLKSM-----APGGRVVVVGNLESGMV 289 Query: 303 SMNPMLLLTGRTWKGAILGGFKSKEC----VPKLVADFMAKKFSLDAL 346 +NP L++ ILG + + + +L A ++F DA+ Sbjct: 290 QLNPGLVIVKEL---EILGAYATTQAELDEALRLTATGGVRQFVTDAV 334 >4UEJ-A nrPDB Length = 346 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 66/224 (29%), Positives = 102/224 (45%), Gaps = 24/224 (10%) Query: 36 EVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAI 95 EVR+K+ + G+CG+D + P+ LGHE +G +++VG GV + PGD V + + Sbjct: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 Query: 96 PQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDE 155 C C C + C K D G+ +DG F++Y VV Sbjct: 87 LPCFTCPECLKGFYSQCAKYDFI---GSRRDG------------------GFAEYIVVKR 125 Query: 156 NAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAA 215 V + P+E I + G A ++A+ + G G +GL AI A Sbjct: 126 KNVFALPTDMPIEDGAFIE-PITVGL-HAFHLAQGCENKNVIIIGAGTIGLLAIQCAVAL 183 Query: 216 GAARIIAVDINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 258 GA + A+DI+ +K A AK GA + N + P +Q VL+E+ Sbjct: 184 GAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLREL 227 >5KIA-A nrPDB Length = 351 Score = 88.2 bits (217), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 87/351 (24%), Positives = 150/351 (42%), Gaps = 50/351 (14%) Query: 35 HEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV 90 ++V IK+ ICGTD H+ P+P+ +GHE G + +G+ V GD+V Sbjct: 34 NDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFSIGDRV 93 Query: 91 IPLAIPQCGKCRICKNPESNYCLKNDVS---NPQGTLQDGTSRFTCRRKPIHHFLGISTF 147 CG CR C+ + C +N V N +G + +L I F Sbjct: 94 SGEGHITCGFCRNCRAGRRHLC-RNTVGVGVNREGAFAE--------------YLAIPAF 138 Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLS 207 + + + E + + + I F +A++ V G + G G +G+ Sbjct: 139 NAFKIPPEIS----------DDLAAIFDPFGNATHTALSFNLV--GEDVLITGAGPIGVM 186 Query: 208 AIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE--MTDGGVDF 265 A+ K GA ++ DIN + A+ +GAT +N ++ +++V+ + MT+ G D Sbjct: 187 AVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVS--RESLRDVMADLHMTE-GFDV 243 Query: 266 SFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKS 325 E+ G + + SLL G ++G+PP + N ++ KG + G Sbjct: 244 GLEMSG-VPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVIF------KGLEIKGIYG 296 Query: 326 KECVP---KLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTIL 373 +E K+VA + L +ITH + +GF + SG+S + IL Sbjct: 297 REMFETWYKMVA-MLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVIL 346 >4ILK-A nrPDB Length = 359 Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 96/363 (26%), Positives = 144/363 (39%), Gaps = 54/363 (14%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSG-TMVTPLPVILGHEAA 71 ++L E SI E E+ P A EVR+K+ GICG+D H+ G P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 72 GIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRF 131 G++++VGEGV + + G++V + CG C C + N C V G DG Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAV---LGVHADG---- 135 Query: 132 TCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIG----CGFSTGYGSAVNV 187 FS+Y VV KI A + +I TG+G Sbjct: 136 --------------GFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQP--- 178 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAA-GAARIIAVDINKDKFAKAKELGATECINPQD 246 T T V+G G +GL+ + K +I D ++ KAKE GA IN + Sbjct: 179 ---TENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--N 233 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS---QNLS 303 + P+ E SF G T++ C +V + P S Sbjct: 234 SQTPLGE------------SFAEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFS 281 Query: 304 MNPMLLLTGRTWKGAILGGFKSKECVPKL--VADFMAKKF-SLDALITHVLPFEKINEGF 360 P ++ + G L F S+ K V D+++K + LITH F+ + + Sbjct: 282 SEPSEVIQ-QGITGKELSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAI 340 Query: 361 DLL 363 L Sbjct: 341 SLF 343 >2H6E-A nrPDB Length = 344 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 102/374 (27%), Positives = 166/374 (44%), Gaps = 52/374 (13%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP---LP 63 ++K KAA+L + +P SIE+V + P+ EV I++ G+C TD V G LP Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGT 123 +ILGHE AG + VGE + VK GD V+ A CR C+ + N C KN + P T Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNIC-KNQII-PGQT 117 Query: 124 LQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENA-VAKIDAASPLEKVCLIGCGFSTGYG 182 G FS+Y +V + + K+++ SP+E L G +T G Sbjct: 118 TNGG-------------------FSEYMLVKSSRWLVKLNSLSPVEAAPLADAG-TTSMG 157 Query: 183 S---AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAK--AKELG 237 + A+ V G+GG+ + I KA I V I++ K + A ELG Sbjct: 158 AIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKAL-MKNITIVGISRSKKHRDFALELG 216 Query: 238 ATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM--MASLLCCHEACGTSVIVG 294 A +D + ++ ++TDG G + +++G +T + LL G ++VG Sbjct: 217 ADYVSEMKD----AESLINKLTDGLGASIAIDLVGTEETTYNLGKLLAQE---GAIILVG 269 Query: 295 VPPDSQNLSMNPM-LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPF 353 + + + +S+ + + G+ G E V +L K + + +P Sbjct: 270 M--EGKRVSLEAFDTAVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYIIK------VPL 321 Query: 354 EKINEGFDLLHSGK 367 + IN+ F L G+ Sbjct: 322 DDINKAFTNLDEGR 335 >1YKF-A nrPDB Length = 352 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 98/345 (28%), Positives = 154/345 (44%), Gaps = 30/345 (8%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVTTV 84 E E P + ++ +AV C +D H V G + +ILGHEA G V VG V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 85 KPGDKVI-PLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143 KPGD+V+ P P + + + G + G +F+ + + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW-KFSNVKDGV----- 119 Query: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 F D N +A + PLE +I +TG+ A +A + G+T AV G+G Sbjct: 120 FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAVLGIGP 177 Query: 204 VGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-G 262 VGL A+ G K GA RIIAV AK GAT+ +N +D PI+ + +T+G G Sbjct: 178 VGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEGKG 235 Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL---LTGRTWKGAI 319 VD + G D +MA+ + + GT V + + L + + + +T KG + Sbjct: 236 VDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGL 294 Query: 320 LGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLL 363 G + + + +L+ K+ L+THV F+ I + F L+ Sbjct: 295 CPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >3TWO-A nrPDB Length = 348 Score = 85.5 bits (210), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 85/316 (26%), Positives = 135/316 (42%), Gaps = 35/316 (11%) Query: 17 ELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL-PVILGHEAAGIVE 75 E KP V P +V I ++ GIC +D H + P+I GHE AGI++ Sbjct: 15 EHFKPHDFSRHAVGP---RDVLIDILYAGICHSDIHSAYSEWKEGIYPMIPGHEIAGIIK 71 Query: 76 SVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCR 134 VG+GV K GD V + + C C+ CK + +C K + C Sbjct: 72 EVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKV------------VFTYDCL 119 Query: 135 RKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194 + + +S VVDEN V +D +PLEKV + C T Y S + +KVT G+ Sbjct: 120 DSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTY-SPLKFSKVTKGT 178 Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQE 253 V G GG+G A+ A G A + N+ K A +G +P+ K+ + Sbjct: 179 KVGVAGFGGLGSMAVKYAVAMG-AEVSVFARNEHKKQDALSMGVKHFYTDPKQCKEELDF 237 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--DSQNLSMNPMLLLT 311 ++ + +++ L + + G +VG+PP + LS+ + L Sbjct: 238 IISTIPT-----HYDLKDYLKLLTYN--------GDLALVGLPPVEVAPVLSVFDFIHLG 284 Query: 312 GRTWKGAILGGFKSKE 327 R G+++GG K + Sbjct: 285 NRKVYGSLIGGIKETQ 300 >5ENV-A nrPDB Length = 347 Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 86/294 (29%), Positives = 124/294 (42%), Gaps = 29/294 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGH 68 K + +E +++ V PKA+E+ I + G+C TD H G P LP++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E AG+V +GE V K GD I C C C+ + C D+S G DG Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLS---GYTHDG 123 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 +F QY D A I + L +V I C T Y A+ Sbjct: 124 ------------------SFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKS 164 Query: 188 AKVTPGSTCAVFG-LGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG+G A+ KA G R++ +D + K + +G I+ Sbjct: 165 ANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTK 223 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 K + VLK TDGG V + AS A GT+V+VG+P ++ Sbjct: 224 EKDIVGAVLK-ATDGGAHGVINVSVSEAAIEASTRYV-RANGTTVLVGMPAGAK 275 >3FPL-A nrPDB Length = 351 Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 102/340 (30%), Positives = 156/340 (45%), Gaps = 36/340 (10%) Query: 34 AHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIP 92 +++ ++ +AV C +D H V G + +ILGHEA G V VG V KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVI- 82 Query: 93 LAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTV 152 +P C P+ Q Q ++ K + G+ F +Y Sbjct: 83 --VP-------CTTPDWRSL------EVQAGFQQHSNGMLAGWKFSNFKDGV--FGEYFH 125 Query: 153 VDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIM 210 V++ +A + PLE +I +TG+ A +A + G+T AV G+G VGL A+ Sbjct: 126 VNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAVLGIGPVGLMAVA 184 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDFSFEV 269 G K GA RIIAV AK GAT+ +N +D PI+ + +T+G GVD + Sbjct: 185 GAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEGKGVDAAIIA 242 Query: 270 IGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL----LTGRTWKGAIL-GGFK 324 G D +MA+ + + GT V + + L + P L + +T KG + GG Sbjct: 243 GGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPV-PRLEWGCGMAHKTIKGGLCPGGRL 300 Query: 325 SKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLL 363 E + +V + + L L+THV F+ I E L+ Sbjct: 301 RAEMLRDMV---VYNRVDLSKLVTHVYHGFDHIEEALLLM 337 >1R37-A nrPDB Length = 347 Score = 84.3 bits (207), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 101/379 (26%), Positives = 164/379 (43%), Gaps = 49/379 (12%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT---------MVTP 61 +A L E+ KP S++E+ V PK +V IK+ A G+C +D H+ G + Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C +P+ Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC-----DSPR 116 Query: 122 GTLQDGTSRFTCRRKPIHHFLGIS---TFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGF 177 +LGI+ +++Y +V + K+ + +E L G Sbjct: 117 -------------------WLGINFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGI 157 Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVGLS-AIMGCKAAGAARIIAVDINKDKFAKAKEL 236 +T AV A + P T V G GG + A+ KA A II VD+ ++ AK Sbjct: 158 TT--YRAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRA 215 Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 GA IN + P+ E+ + GVD ++ T+ + G V+VG+ Sbjct: 216 GADYVINA-SMQDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQ-GKYVMVGLF 273 Query: 297 PDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKI 356 + P++ L+ + G+++G + +L A+ + +IT + E+ Sbjct: 274 GADLHYHA-PLITLSEIQFVGSLVGNQSDFLGIMRL-----AEAGKVKPMITKTMKLEEA 327 Query: 357 NEGFDLLHSGKSI-RTILM 374 NE D L + K+I R +L+ Sbjct: 328 NEAIDNLENFKAIGRQVLI 346 >4OH1-A nrPDB Length = 351 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 72/255 (28%), Positives = 113/255 (44%), Gaps = 38/255 (14%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVVSG-------TMVTPLPVILGHEAAGIVESVG 78 E + PK E+RIK+V ICG+D H+++G T + LP+ GHE +G+++ VG Sbjct: 25 EAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVIDKVG 84 Query: 79 EGVTTV--KPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRK 136 + K G KV+ CG C C+ + N C SN G +G S + Sbjct: 85 STAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLC-----SN-MGYRMNGFSEYA---- 134 Query: 137 PIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTC 196 ++H I + + D+ + PL V L S+ AK++ G + Sbjct: 135 -VYHMSQI-----FPIPDDADLKDYALVEPL-TVAL----------SSAEQAKISYGKSV 177 Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 A+ G GG+G+ + + AGA+ I DI +K A E GA +N + + + E Sbjct: 178 AIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EGVAERAI 235 Query: 257 EMTDGGVDFSFEVIG 271 E+ G D E G Sbjct: 236 ELAGGRYDCVLEGTG 250 >4JLW-A nrPDB Length = 399 Score = 81.3 bits (199), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 71/214 (33%), Positives = 105/214 (49%), Gaps = 28/214 (13%) Query: 35 HEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 H V +++V+ ICG+D H+V G P ++LGHE G V +G GV T+K GD V +P Sbjct: 35 HGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEITGEVVEIGRGVETMKIGDLVSVPF 94 Query: 94 AIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTF----SQ 149 + CG CR CK + CL NP R + ++ + + ++ Sbjct: 95 NV-ACGHCRTCKEQHTGVCL---TVNP------------ARAGGAYGYVDMGGWVGGQAE 138 Query: 150 YTVV---DENAVAKIDAASPLEKVCLIGCG---FSTGYGSAVNVAKVTPGSTCAVFGLGG 203 Y +V D N + + + +EK+ + C TGY AV A V PGST + G G Sbjct: 139 YVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGAVT-AGVGPGSTVYIAGAGP 197 Query: 204 VGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 VGL+A + GAA +I D+N + A AK+ G Sbjct: 198 VGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQG 231 >5YAT-A nrPDB Length = 350 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 76/256 (29%), Positives = 111/256 (43%), Gaps = 27/256 (10%) Query: 11 KAAVLWELKK-PFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT--MVTPLPVILG 67 + AV++E P +++ V PK++E+ I + G+C TD H G + LP++ G Sbjct: 9 QKAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGG 68 Query: 68 HEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 HE AG+V + GE VT + GD I C C C + C K D+S G D Sbjct: 69 HEGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLS---GFTHD 125 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 G +F QY D A+I + L +V I C T Y A+ Sbjct: 126 G------------------SFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALK 166 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG S + A R++ +D DK K LGA ++ Sbjct: 167 TADLRIGQWVAISGAGGGLGSLAVQYAKALGLRVLGIDGGADKGEFVKSLGAEVFVDFTK 226 Query: 247 YKKPIQEVLKEMTDGG 262 K + EV K +T+GG Sbjct: 227 TKDVVAEVQK-LTNGG 241 >3IP1-A nrPDB Length = 404 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 95/381 (24%), Positives = 159/381 (41%), Gaps = 58/381 (15%) Query: 24 IEEV-EVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTP----LPVILGHEAAGIV 74 +EEV E K E+ IK+ A GICG+D H+ G ++ P PV LGHE +G+V Sbjct: 44 VEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFSGVV 103 Query: 75 ESVGEGVTTVKP------GDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGT 128 G + G+ V + CG CR C N+C + N G DG Sbjct: 104 VEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHC---ENLNELGFNVDGA 160 Query: 129 SRFTCRRKPIHHFLGISTFSQYTVVDEN---AVAKIDAASPLEKVCLIGCGF---STGYG 182 F++Y VD ++ +++ +++ L G S Y Sbjct: 161 ------------------FAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYN 202 Query: 183 SA-VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 + V + PG + G G +GL+A+ K AGA+++I + ++ + AKELGA Sbjct: 203 AVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHV 262 Query: 242 INPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASL-LCCHEACGTSVIVGVPPDS 299 I+P K+ E + + T+G G E G + + A G + V + + Sbjct: 263 IDPT--KENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINATVAIVARA 320 Query: 300 QNLSMNPMLLLTGRTW---KGAILG--GFKSKECVPKLVADFMAKKFSLDALITHVLPFE 354 + + LTG + + I+G G P++++ MA + +I+ + E Sbjct: 321 -----DAKIPLTGEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTVSME 374 Query: 355 KINEGFDLLHSGKSIRTILMF 375 +I E L + KS+ + M Sbjct: 375 EIPEYIKRLQTDKSLVKVTML 395 >1KOL-A nrPDB Length = 398 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 70/214 (32%), Positives = 101/214 (47%), Gaps = 28/214 (13%) Query: 35 HEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 H V +K+V+ ICG+D H+V G + ++LGHE G V G V ++ GD V +P Sbjct: 34 HGVILKVVSTNICGSDQHMVRGRTTAQVGLVLGHEITGEVIEKGRDVENLQIGDLVSVPF 93 Query: 94 AIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFS----Q 149 + CG+CR CK + CL NP R + ++ + ++ + Sbjct: 94 NV-ACGRCRSCKEMHTGVCL---TVNP------------ARAGGAYGYVDMGDWTGGQAE 137 Query: 150 YTVV---DENAVAKIDAASPLEKVCLIGCG---FSTGYGSAVNVAKVTPGSTCAVFGLGG 203 Y +V D N + D +EK+ + C TGY AV A V PGST V G G Sbjct: 138 YVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAVT-AGVGPGSTVYVAGAGP 196 Query: 204 VGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 VGL+A + GAA +I D+N + A AK G Sbjct: 197 VGLAAAASARLLGAAVVIVGDLNPARLAHAKAQG 230 >3FSR-A nrPDB Length = 352 Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 91/349 (26%), Positives = 146/349 (41%), Gaps = 38/349 (10%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVTTV 84 E E P + ++ +AV C +D H V G + +ILGHEA G V VG V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 85 KPGDKVI-PLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143 KPGD+V+ P P + + + G + G +F+ + + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW-KFSNVKDGV----- 119 Query: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 F D N +A + PLE +I +TG+ A +A + GS+ V G+G Sbjct: 120 FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVVIGIGA 177 Query: 204 VGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGV 263 VGL I G K GA RII V AK GAT+ +N ++ + +V+K GV Sbjct: 178 VGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTNGKGV 236 Query: 264 DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL--------LTGRTW 315 D G +T+ ++ S I + + S + +L+ + +T Sbjct: 237 DRVIMAGGGSETLSQAVSMVKPGGIISNI------NYHGSGDALLIPRVEWGCGMAHKTI 290 Query: 316 KGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLL 363 KG + G + + + +L+ K+ L+THV F+ I + F L+ Sbjct: 291 KGGLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >1KEV-A nrPDB Length = 351 Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 71/234 (30%), Positives = 106/234 (45%), Gaps = 23/234 (9%) Query: 34 AHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIP 92 +++ ++ +AV C +D H V G + +ILGHEA G V VG V KPGD+VI Sbjct: 24 SYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVI- 82 Query: 93 LAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTV 152 +P C P+ Q Q ++ K + G+ F +Y Sbjct: 83 --VP-------CTTPDWRSL------EVQAGFQQHSNGMLAGWKFSNFKDGV--FGEYFH 125 Query: 153 VDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIM 210 V++ +A + PLE +I +TG+ A +A + GS+ V G+G VGL I Sbjct: 126 VNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVVVIGIGAVGLMGIA 184 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 G K GA RII V AK GAT+ +N ++ + +V+K GVD Sbjct: 185 GAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTNGKGVD 237 >3FPC-A nrPDB Length = 352 Score = 71.2 bits (173), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 105/243 (43%), Gaps = 25/243 (10%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVTTV 84 E E P + ++ +AV C +D H V G + +ILGHEA G V VG V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 85 KPGDKVI-PLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG 143 KPGD+V+ P P + + + G + G +F+ + + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW-KFSNVKDGV----- 119 Query: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 F D N +A + PLE +I +TG+ A +A + G T V G+G Sbjct: 120 FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDTVCVIGIGP 177 Query: 204 VGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDG 261 VGL ++ G GA RI AV K A E GAT+ IN YK ++++LK Sbjct: 178 VGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIIN---YKNGDIVEQILKATDGK 234 Query: 262 GVD 264 GVD Sbjct: 235 GVD 237 >5H82-A nrPDB Length = 389 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 91/343 (26%), Positives = 144/343 (41%), Gaps = 33/343 (9%) Query: 35 HEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 H+V+ K++ G+C D T T P + GHE GIV +G V K GDKV + Sbjct: 54 HDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVGVG 113 Query: 93 LAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLG-------IS 145 I CGKC C YC P+ DGT+ F+ ++ + Sbjct: 114 NFIGSCGKCERCNEGLEPYC-------PKVIYTDGTA-FSDENNTVYGDVSGDGEDRIYG 165 Query: 146 TFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVG 205 +S V +E V + PL I CG Y + PG + V G G +G Sbjct: 166 GYSNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIG 225 Query: 206 LSAIMGCKAAGA-ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 A+ KA GA +I+ I+K + A K I+ K+P + E T G+ Sbjct: 226 KLAVKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLIS----KEPEEMKAAESTLDGI- 280 Query: 265 FSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFK 324 F+ + + + LL + GT V++GV ++ L ++P LL+ R + G+I G K Sbjct: 281 --FDCVPSV-HPLHPLLNLLKFEGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMK 336 Query: 325 SKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 + + DF AK + + ++P + +N + + G Sbjct: 337 ETQ----EMLDFAAKHNIVSDI--ELIPMDYVNTALERIAKGN 373 >1E3J-A nrPDB Length = 352 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 63/211 (29%), Positives = 97/211 (45%), Gaps = 29/211 (13%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILG 67 +AVL++ + +E+ + PK EV ++M VGICG+D H + P+++G Sbjct: 7 SAVLYK-QNDLRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 68 HEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 HEA+G V VG+ V +K GD+V + +P C +C+ CK + N C P T Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVP-CRRCQFCKEGKYNLC-------PDLTF-- 115 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 C P ++Y V + K+ LE+ L+ S G A Sbjct: 116 ------CATPPDD-----GNLARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGV-HACR 162 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGA 217 A V G+T V G G +GL +++ KA GA Sbjct: 163 RAGVQLGTTVLVIGAGPIGLVSVLAAKAYGA 193 >2DPH-A nrPDB Length = 398 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 89/307 (28%), Positives = 130/307 (42%), Gaps = 31/307 (10%) Query: 35 HEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 H V +K+V+ ICG+D H+ G + P +LGHE G V G V + GD V +P Sbjct: 33 HAVILKVVSTNICGSDQHIYRGRFIVPKGHVLGHEITGEVVEKGSDVELMDIGDLVSVPF 92 Query: 94 AIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVV 153 + CG+CR CK S+ C +N++ NP L G F + G + + Sbjct: 93 NV-ACGRCRNCKEARSDVC-ENNLVNPDADL--GAFGFDLKGWS----GGQAEYVLVPYA 144 Query: 154 DENAVAKIDAASPLEKV---CLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIM 210 D + D +EK+ LI TG+ V+ A V PGS + G G VG A Sbjct: 145 DYMLLKFGDKEQAMEKIKDLTLISDILPTGFHGCVS-AGVKPGSHVYIAGAGPVGRCAAA 203 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELG--ATECINPQDYKKPIQEVL-KEMTDGGVD-FS 266 G + GAA +I D N ++ + G + N + I ++L K D GVD Sbjct: 204 GARLLGAACVIVGDQNPERLKLLSDAGFETIDLRNSAPLRDQIDQILGKPEVDCGVDAVG 263 Query: 267 FEVIGRLDT--------MMASLLCCHEACGT----SVIVGVPPD--SQNLSMNPMLLLTG 312 FE G D + SL A G + VG PD +++ + L G Sbjct: 264 FEAHGLGDEANTETPNGALNSLFDVVRAGGAIGIPGIYVGSDPDPVNKDAGSGRLHLDFG 323 Query: 313 RTWKGAI 319 + W +I Sbjct: 324 KMWTKSI 330 >1UUF-A nrPDB Length = 369 Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 96/369 (26%), Positives = 154/369 (41%), Gaps = 45/369 (12%) Query: 8 IKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TPLPVIL 66 +K KA + K+P ++ P ++V+I++ G+C +D H V T P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 GHE G V +VG+ V PGD V + + C C C++ NYC + GT Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYC-----DHMTGTYN 135 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIG---CGFSTGYG 182 T +P H G +SQ VV E V +I P E++ + C T Y Sbjct: 136 SPTP-----DEPGHTLGG---YSQQIVVHERYVLRI--RHPQEQLAAVAPLLCAGITTY- 184 Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGA--ARIIAVDINKDKFAKAKELGATE 240 S + + PG V G+G MG K A A A ++A ++ K AK LGA E Sbjct: 185 SPLRHWQAGPGKKVGVV---GIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADE 241 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIG---RLDTMMASLLCCHEACGTSVIVGVPP 297 +N ++ + + LK DF + LD L + GT +VG P Sbjct: 242 VVNSRNADE-MAAHLKSF-----DFILNTVAAPHNLDDFTTLL----KRDGTMTLVGAPA 291 Query: 298 DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKIN 357 L++ R G+++GG + + DF A+ + + ++ ++IN Sbjct: 292 TPHKSPEVFNLIMKRRAIAGSMIGGIPETQ----EMLDFCAEHGIVADI--EMIRADQIN 345 Query: 358 EGFDLLHSG 366 E ++ + G Sbjct: 346 EAYERMLRG 354 >3WLE-A nrPDB Length = 341 Score = 67.8 bits (164), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 81/282 (28%), Positives = 128/282 (45%), Gaps = 34/282 (12%) Query: 25 EEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTV 84 ++ V PKA ++ +K+ AVG+C +D HV+ + ++GHE AG V +VG+ V Sbjct: 27 NDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGTVAAVGDDVINY 86 Query: 85 KPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGI 144 K GD+V + CG C+ C+ N C KN + G DG +L + Sbjct: 87 KVGDRVACVGPNGCGGCKYCRGAIDNVC-KNAFGDWFGLGYDGG---------YQQYLLV 136 Query: 145 STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGV 204 + + + +N A + AAS + T Y A+ +A+V+P S + G GG+ Sbjct: 137 TRPRNLSRIPDNVSADVAAASTDAVL--------TPY-HAIKMAQVSPTSNILLIGAGGL 187 Query: 205 GLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 G +AI KA G A++ +D K+ +AK+LGA + E L E G Sbjct: 188 GGNAIQVAKAFG-AKVTVLDKKKEARDQAKKLGADA----------VYETLPESISPG-- 234 Query: 265 FSFEVIGRLDTMMASLLCCHEACG-TSVIVGVPPDSQNLSMN 305 SF ++ A+ C + VI+ V + NLS N Sbjct: 235 -SFSACFDFVSVQATFDVCQKYVEPKGVIMPVGLGAPNLSFN 275 >4OAQ-A nrPDB Length = 367 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 89/368 (24%), Positives = 156/368 (42%), Gaps = 36/368 (9%) Query: 16 WELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLP---VILGHEAAG 72 W K S E ++ P H+V +K G+C +D H +S PL +++GHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGW-QPLQRDNLVVGHEIIG 75 Query: 73 IVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRF 131 V +VG+ VT K GD+V I A C C+ C + YC + G + + Sbjct: 76 EVIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYC------------KQGAATY 123 Query: 132 TCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV-NVAKV 190 + ++++ +S +++ DE V I P + C T + + N+ Sbjct: 124 NSKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLD 183 Query: 191 TPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 G + G+GG+G A+ A G A + A + K +A +LGA + + + K Sbjct: 184 ARGKNVGIIGIGGLGHLALQFANAMG-ANVTAFSRSSSKKEQAMKLGAHDFVATGEDKTW 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTM-MASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL 309 + D DF +D + ++ L + V VG+PP ++P Sbjct: 243 YKNY-----DDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPFTF 297 Query: 310 L-TGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHV-LPFEKINEGFDLLHSGK 367 L G ++ ++LG SK V +++ +A K ++ +I V + E + D H+G Sbjct: 298 LQQGASFGSSLLG---SKTEVKEMLN--LAAKHNVRPMIEEVPISEENCAKALDRCHAG- 351 Query: 368 SIRTILMF 375 +R +F Sbjct: 352 DVRYRFVF 359 >5VKT-A nrPDB Length = 362 Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 52/164 (31%), Positives = 70/164 (42%), Gaps = 22/164 (13%) Query: 36 EVRIKMVAVGICGTDDHVVSGTMVTPL-PVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +V IK++ GIC TD HV+ + PV+ GHE G+V VG GVT K GD V + Sbjct: 36 DVTIKVLFCGICHTDLHVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAGDTVGVGY 95 Query: 94 AIPQCGKCRICKNPESNYCLKNDVSNPQGTL-QDGTSRFTCRRKPIHHFLGIST---FSQ 149 + C C C NYC P L +G HH G +T FS Sbjct: 96 FVDSCRTCESCSTGHENYC-------PDLVLTSNGVD---------HHHHGATTKGGFSD 139 Query: 150 YTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 193 VV ++ V ++ + PL+ + C T Y A PG Sbjct: 140 VLVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPG 183 >5Z0C-A nrPDB Length = 374 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 95/330 (28%), Positives = 134/330 (40%), Gaps = 42/330 (12%) Query: 36 EVRIKMVAVGICGTDDHVVSGTMV-TPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +V K++ GIC +D H + T P + GHE G V VG V K GDKV + Sbjct: 40 DVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGC 99 Query: 94 AIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVV 153 + C C C N NYC N + DGT L +S VV Sbjct: 100 IVGSCHSCPNCNNHLENYC-PNRILTFGSRYYDGT-------------LNHGGYSDLMVV 145 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCK 213 E+ +I A PL+ + C T Y PG V GLGG+G A+ K Sbjct: 146 QEHFAVRIPDALPLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAK 205 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 A G + K LGA I D ++ +Q + M G + Sbjct: 206 AFGVKVTVVSTSPAKKEDAISGLGAHSFILSTDAEQ-MQAAVGTMD-----------GII 253 Query: 274 DTMMAS-----LLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTW-KGAILGGFKSKE 327 DT+ AS L+ ++ G V+VG PP L + P+LL GR G+ +GG K + Sbjct: 254 DTVSASHPLPPLISLLKSHGKLVMVGDPPKPLELPVFPLLL--GRKMVAGSAIGGMKETQ 311 Query: 328 CVPKLVADFMAKKFSLDALITHVLPFEKIN 357 + DF AK+ + A + V+P + +N Sbjct: 312 ----EMIDFAAKE-GVRADV-EVIPMDYVN 335 >2OUI-A nrPDB Length = 360 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 69/230 (30%), Positives = 102/230 (44%), Gaps = 25/230 (10%) Query: 39 IKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVI-PLAIP 96 ++ +A+ C +D H V +G + +ILGHEA G + VG V +K GDKVI P P Sbjct: 29 VRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRLKVGDKVIVPAITP 88 Query: 97 QCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDEN 156 G+ + + Y + + G L G +F+ + + S D N Sbjct: 89 DWGE----EESQRGYPM-----HSGGML--GGWKFSNFKDGV-----FSEVFHVNEADAN 132 Query: 157 AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAG 216 P E ++ +TG+ A +A + G T V G+G VGL ++ G G Sbjct: 133 LALLPRDIKP-EDAVMLSDMVTTGFHGA-ELANIKLGDTVCVIGIGPVGLMSVAGANHLG 190 Query: 217 AARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264 A RI AV K A E GAT+ IN YK ++++LK GVD Sbjct: 191 AGRIFAVGSRKHCCDIALEYGATDIIN---YKNGDIVEQILKATDGKGVD 237 >3M6I-A nrPDB Length = 363 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 85/361 (23%), Positives = 153/361 (42%), Gaps = 49/361 (13%) Query: 15 LWELKKPFSIEEVEVAPP-KAHEVRIKMVAVGICGTDDHVVSGTMVTPLPV----ILGHE 69 LW + S+E V+ K EV + + + GICG+D H + P+ V +LGHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKND-VSNP--QGTLQD 126 +AG V +V V ++K GD+V C C C N C + D +S P G L+ Sbjct: 80 SAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLLR- 138 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 R+ H +G ++ +++ +VA + + Sbjct: 139 ---RYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQ 173 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A V G + G G +GL ++ KAAGA ++ DI++ + AKE+ E + + Sbjct: 174 RAGVRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEI-CPEVVTHKV 232 Query: 247 YKKPIQEVLKEMTD--GGVD--FSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 + +E K++ + GG++ + E G +++ +A+ + + G ++GV +N Sbjct: 233 ERLSAEESAKKIVESFGGIEPAVALECTG-VESSIAAAIWAVKFGGKVFVIGV---GKNE 288 Query: 303 SMNPMLLLTGRTWKGAILGGFKSKEC--VPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 P + + R + F+ + C P+ + L L+TH P E + F Sbjct: 289 IQIPFMRASVRE----VDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAF 344 Query: 361 D 361 + Sbjct: 345 E 345 >5FI5-A nrPDB Length = 357 Score = 60.8 bits (146), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 81/311 (26%), Positives = 123/311 (39%), Gaps = 48/311 (15%) Query: 35 HEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 H+V++K++ G C D + T P +LGHE G V VG V K GDKV + Sbjct: 43 HDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVGVA 102 Query: 93 LAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTV 152 I CGKC +C N NYC P+ D ++ C S V Sbjct: 103 SIIETCGKCEMCTNEVENYC-------PEAGSID-SNYGAC--------------SNIAV 140 Query: 153 VDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGC 212 ++EN V + PL+ + C T Y PG + GLGG+G A+ Sbjct: 141 INENFVIRWPENLPLDSGVPLLCAGITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALRFA 200 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECI---NPQDYKKPIQEVLKEMTDGGVDFSFEV 269 KA GA + K K ++ GA + NP++ + G +D Sbjct: 201 KAFGAKVTVISSSLKKKREAFEKFGADSFLVSSNPEEMQG---------AAGTLD----- 246 Query: 270 IGRLDTM-----MASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFK 324 G +DT+ + LL + G +I+G P + P LL+ G+ + G K Sbjct: 247 -GIIDTIPGNHSLEPLLALLKPLGKLIILGAPEMPFEVPA-PSLLMGGKVMAASTAGSMK 304 Query: 325 SKECVPKLVAD 335 + + + A+ Sbjct: 305 EIQEMIEFAAE 315 >6DKH-A nrPDB Length = 346 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 69/279 (24%), Positives = 109/279 (39%), Gaps = 32/279 (11%) Query: 39 IKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLA 94 +++ GICG+D H G + P++LGHE G V + + + G V Sbjct: 35 VQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINP 92 Query: 95 IPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVD 154 CG C+ C N C RF H G F++Y +V+ Sbjct: 93 SKPCGHCKYCIEHNENQCTD--------------MRFFGSAMYFPHVDG--GFTRYKMVE 136 Query: 155 ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKA 214 + A + EKV + +A ++ G + G+G +G + K Sbjct: 137 TSQCVPYPAKAD-EKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVKT 194 Query: 215 AGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLD 274 GAA I+ D++ + KE+GA +NPQ+ + K G D SFEV G Sbjct: 195 LGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEK----GYFDVSFEVSGHPS 250 Query: 275 TMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGR 313 ++ L A G V VG+ ++ PM+ L G+ Sbjct: 251 SVNTCLEVT-RARGVMVQVGM---GGAMAEFPMMTLIGK 285 >3UOG-A nrPDB Length = 363 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 70/268 (26%), Positives = 110/268 (41%), Gaps = 48/268 (17%) Query: 17 ELKKPFSIEEVEVAPPKA--HEVRIKMVAVGICGTDDHVVSGTMVTPL--PVILGHEAAG 72 E P ++ E P+A H++ ++ +AV + D V+ M L P + + +G Sbjct: 34 ETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSG 93 Query: 73 IVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 +VE+VG+ VT +PGD+VI P L+ GT Sbjct: 94 VVEAVGKSVTRFRPGDRVISTFAPGW----------------------LDGLRPGTG--- 128 Query: 133 CRRKPIHHFLGIS---TFSQYTVVDEN----AVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 R P + LG + S+Y V+ E A +DAA + + C T + + V Sbjct: 129 --RTPAYETLGGAHPGVLSEYVVLPEGWFVAAPKSLDAA----EASTLPCAGLTAWFALV 182 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-- 243 + G V G GGV L + KA G A +I +++K +A LGA IN Sbjct: 183 EKGHLRAGDRVVVQGTGGVALFGLQIAKATG-AEVIVTSSSREKLDRAFALGADHGINRL 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIG 271 +D+ ++ V D G D E+ G Sbjct: 242 EEDW---VERVYALTGDRGADHILEIAG 266 >2VCY-A nrPDB Length = 344 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 62/250 (24%) Query: 20 KPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT--MVTPLPVILGHEAAGIVESV 77 K ++ +E+A + +VR+KM+A I +D +++ G ++ LP + G+E V +V Sbjct: 27 KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAV 86 Query: 78 GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP 137 G VT +KPGD VIP Sbjct: 87 GSNVTGLKPGDWVIPANA------------------------------------------ 104 Query: 138 IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STC 196 G+ T+ V E A+ ++ + PL+ +G T Y ++ ++ PG S Sbjct: 105 -----GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 159 Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAV-----DINK--DKFAKAKELGATECINPQDYKK 249 GVG A++ AA R I V DI K D+ K LGA I ++ ++ Sbjct: 160 QNASNSGVG-QAVIQIAAALGLRTINVVRDRPDIQKLSDRL---KSLGAEHVITEEELRR 215 Query: 250 P-IQEVLKEM 258 P ++ K+M Sbjct: 216 PEMKNFFKDM 225 >1WLY-A nrPDB Length = 333 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 76/284 (26%), Positives = 117/284 (41%), Gaps = 67/284 (23%) Query: 12 AAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT----MVTPLPVI 65 AAV+ + P F EEV+V P +VR++ A+G+ D + +G +V P++ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPPIV 63 Query: 66 LGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 +G EAA +VE VG GVT G+ R+C CL Sbjct: 64 VGFEAAAVVEEVGPGVTDFTVGE-------------RVCT------CLPP---------- 94 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGC---GFSTGYG 182 + +SQ + + K+ L+ V L G G + Y Sbjct: 95 ------------------LGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQY- 135 Query: 183 SAVNVAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 KV PG + GG+G + + GA +I ++K A++LG Sbjct: 136 LLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGAT-VIGTVSTEEKAETARKLGCHHT 194 Query: 242 IN--PQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLC 282 IN QD+ EV++E+T G GVD ++ IG+ DT+ SL C Sbjct: 195 INYSTQDFA----EVVREITGGKGVDVVYDSIGK-DTLQKSLDC 233 >1YQX-A nrPDB Length = 366 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 77/307 (25%), Positives = 124/307 (40%), Gaps = 30/307 (9%) Query: 36 EVRIKMVAVGICGTDDHVVSGTM-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IPL 93 +VR K++ G+C +D H + + P++ GHE G V VG V V GDKV + Sbjct: 43 DVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVGVGC 102 Query: 94 AIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVV 153 + C C C N NYC K ++ DGT + +S + V Sbjct: 103 LVGACHSCESCANDLENYCPKMILTYAS-IYHDGTITY-------------GGYSNHMVA 148 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCK 213 +E + + PL+ + C T Y PG + GLGG+G A+ K Sbjct: 149 NERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVAVKFAK 208 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 A G+ + K K GA + +D QE ++ G +D + + + Sbjct: 209 AFGSKVTVISTSPSKKEEALKNFGADSFLVSRD-----QEQMQAAA-GTLDGIIDTVSAV 262 Query: 274 DTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTW-KGAILGGFKSKECVPKL 332 ++ L ++ G ++VG P + L + L+ GR G+ +GG K + Sbjct: 263 HPLLP-LFGLLKSHGKLILVGAP--EKPLELPAFSLIAGRKIVAGSGIGGMKETQ----E 315 Query: 333 VADFMAK 339 + DF AK Sbjct: 316 MIDFAAK 322 >1QOR-A nrPDB Length = 327 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 31/74 (41%), Positives = 44/74 (59%), Gaps = 3/74 (4%) Query: 21 PFSIEEVEVAP--PKAHEVRIKMVAVGICGTDDHVVSGTMVTP-LPVILGHEAAGIVESV 77 P ++ VE P P +E++++ A+GI D ++ SG P LP LG EAAGIV V Sbjct: 13 PEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGIVSKV 72 Query: 78 GEGVTTVKPGDKVI 91 G GV +K GD+V+ Sbjct: 73 GSGVKHIKAGDRVV 86 Score = 34.3 bits (77), Expect = 0.083, Method: Compositional matrix adjust. Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Query: 202 GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 GGVGL A KA G A++I K A + GA + IN ++ + + E LKE+T G Sbjct: 151 GGVGLIACQWAKALG-AKLIGTVGTAQKAQSALKAGAWQVINYRE--EDLVERLKEITGG 207 Query: 262 -GVDFSFEVIGRLDTMMASLLCCHE 285 V ++ +GR DT SL C Sbjct: 208 KKVRVVYDSVGR-DTWERSLDCLQR 231 >2CDC-A nrPDB Length = 366 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 9/83 (10%) Query: 36 EVRIKMVAVGICGTDDHVVSGTM-VTPLP-----VILGHEAAGIVESVGEGVTTVKPGDK 89 +++I+ + GICG D +V+G + ++ LP ++LGHEA G+VE G + GD Sbjct: 28 KIKIRTIYNGICGADREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYHGFSQ---GDL 84 Query: 90 VIPLAIPQCGKCRICKNPESNYC 112 V+P+ CG CR C ++C Sbjct: 85 VMPVNRRGCGICRNCLVGRPDFC 107 >3QWB-A nrPDB Length = 334 Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 97/261 (37%), Gaps = 57/261 (21%) Query: 25 EEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTV 84 E+ V E+ IK G+ + + G P +LG EA+G V + G+GVT Sbjct: 26 EDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGVTNF 85 Query: 85 KPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGI 144 + GD+V ++ Sbjct: 86 EVGDQV-------------------------------------------------AYISN 96 Query: 145 STFSQYT-VVDENAVAKIDAASPLEKVCLIGCGFS---TGYGSAVNVAKVTPGSTCAVFG 200 STF+QY+ + + V K+ + E++ L G T V G +F Sbjct: 97 STFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFA 156 Query: 201 L-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 GGVGL K GA IAV +K AKE GA IN + +++VLK Sbjct: 157 AAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINASK-EDILRQVLKFTN 214 Query: 260 DGGVDFSFEVIGRLDTMMASL 280 GVD SF+ +G+ DT SL Sbjct: 215 GKGVDASFDSVGK-DTFEISL 234 >1YB5-A nrPDB Length = 351 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 85/385 (22%), Positives = 155/385 (40%), Gaps = 66/385 (17%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIE---EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT 57 M+T K+++ A ++E P ++ ++ V PK H+V IK+ A G+ + ++ SGT Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 58 MVTP--LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKN 115 LP G + AG++E+VG+ + K GD+V + G + Y L Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGY--------AEYALAA 132 Query: 116 DVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 D + V K+ ++ IG Sbjct: 133 D---------------------------------------HTVYKLPEKLDFKQGAAIGI 153 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK 234 + T Y + ++ A V G + V G GGVGL+A +A G +I+ ++ Sbjct: 154 PYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVL 212 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + GA E N ++ I ++ K + + G+D E++ ++ L H G ++VG Sbjct: 213 QNGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSH--GGRVIVVG 269 Query: 295 VPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMA--KKFSLDALITHVLP 352 + +NP + + + +KE + A A + L +I P Sbjct: 270 ---SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYP 326 Query: 353 FEKINEGFD-LLH-SGKSIRTILMF 375 EK+ E + ++H SG + + IL+ Sbjct: 327 LEKVAEAHENIIHGSGATGKMILLL 351 >1Q1N-A nrPDB Length = 360 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 43/159 (27%), Positives = 69/159 (43%), Gaps = 17/159 (10%) Query: 31 PPKAHEVRIKMVAVGICGTDDHVVSGTMVT-PLPVILGHEAAGIVESVG-EGVTTVKPGD 88 P H++ IK+ A G+CG+D H +G +P+++GHE G V +G + + +K G Sbjct: 30 PFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKVGQ 89 Query: 89 KV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTF 147 +V + + C +C CKN YC K + Q +DG ++ + Sbjct: 90 RVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQ-PYEDG-------------YVSQGGY 135 Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 + Y V E+ V I P + CG T Y V Sbjct: 136 ANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVR 174 >3SLK-A nrPDB Length = 795 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 58/237 (24%), Positives = 89/237 (37%), Gaps = 69/237 (29%) Query: 16 WELK--KPFSI-------EEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVIL 66 W L+ +P S+ E AP EVRI M A G+ D + G + P L Sbjct: 211 WRLEATRPGSLDGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALG--MYPGVASL 268 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 G E AG+V G GVT + PGD+V+ + IP+ Sbjct: 269 GSEGAGVVVETGPGVTGLAPGDRVMGM-IPKA---------------------------- 299 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 F V D V +I A + + F T Y + V+ Sbjct: 300 --------------------FGPLAVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVD 339 Query: 187 VAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAA--------RIIAVDINKDKFAKAK 234 +A + PG + V GGVG++AI + GA + AV+++++ A ++ Sbjct: 340 LAGLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATASEDKWQAVELSREHLASSR 396 >3WID-A nrPDB Length = 369 Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 8/93 (8%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTPLP-----VILGHEAAGIVESVGE 79 ++++ P+ +E ++K V +GICGTD V+G + T P ++LGHEA V V + Sbjct: 20 KIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLQVLDVSD 79 Query: 80 GVTTVKPGDKVIPLAIPQCGKCRICKNPESNYC 112 +K GD V+PL + + GKC C+ + C Sbjct: 80 N-NYIKRGDFVVPL-VRRPGKCVNCRIGRQDNC 110 >5H83-A nrPDB Length = 360 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 35 HEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILGHEAAGIVESVGEGVTTVKPGDKV-IP 92 ++V+ K++ G C D + + +T P ++GHE G+V +G V K GDKV + Sbjct: 40 NDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVGVG 99 Query: 93 LAIPQCGKCRICKNPESNYCLK 114 + C KC +C N N C K Sbjct: 100 GFVGACEKCEMCVNGVENNCSK 121 >3JYN-A nrPDB Length = 325 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 40/122 (32%), Positives = 58/122 (47%), Gaps = 7/122 (5%) Query: 21 PFSIEEVEVAP--PKAHEVRIKMVAVGICGTDDHVVSGTMVTP-LPVILGHEAAGIVESV 77 P +E V+ P P V ++ A+G+ D + SG P LP LG E AG+VE+V Sbjct: 13 PEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVVEAV 72 Query: 78 GEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYC-LKNDVSNPQGT---LQDGTSRFTC 133 G+ VT K GD+V P + PE+N L + VS Q L+ T ++ Sbjct: 73 GDEVTRFKVGDRVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQYLL 132 Query: 134 RR 135 R+ Sbjct: 133 RQ 134 >3B70-A nrPDB Length = 371 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 78/357 (21%), Positives = 130/357 (36%), Gaps = 72/357 (20%) Query: 36 EVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAI 95 +V +++ AV I +D + G TP LG + AG V +VG VT ++ GD+V Sbjct: 38 QVYVRVEAVAINPSDTKM-RGQFATPW-AFLGTDYAGTVVAVGSDVTHIQVGDRV----- 90 Query: 96 PQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDE 155 Y +N++ C R P FSQYTV Sbjct: 91 ---------------YGAQNEM---------------CPRTPDQ-----GAFSQYTVTRG 115 Query: 156 NAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV---------AKVTPGSTCAVFGL--GGV 204 AKI E+ + G ST G A+ + A P + V+ L GG Sbjct: 116 RVWAKIPKGLSFEQAAALPAGISTA-GLAMKLLGLPLPSPSADQPPTHSKPVYVLVYGGS 174 Query: 205 GLSAIMGCKAAGAARIIAVDI-NKDKFAKAKELGATECINPQDYKKP-IQEVLKEMTDGG 262 +A + + + I + + F AK GA E DY+ P + + ++ T Sbjct: 175 TATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVF---DYRAPNLAQTIRTYTKNN 231 Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD--------SQNLSMNPMLLLTGRT 314 + ++ + I +++ A G V + P+ + + ++ P + G T Sbjct: 232 LRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMVTTDWTLGPTIFGEGST 291 Query: 315 WKGAILGGFKSKECVPKLVADF--MAKKFSLDALITHVLPFEKINEGFDLLHSGKSI 369 W G E + D +A + D + H P + GFD + G + Sbjct: 292 WPAPY--GRPGSEEERQFGEDLWRIAGQLVEDGRLVH-HPLRVVQGGFDHIKQGMEL 345 >3FBG-A nrPDB Length = 346 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 54/234 (23%), Positives = 89/234 (38%), Gaps = 58/234 (24%) Query: 22 FSIEEVEVAPPKAHE--VRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGE 79 F +++ PK HE V+I+ ++V T ++ V+ P +LG +A G+VESVG Sbjct: 20 FKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMD---VSKAPRVLGFDAIGVVESVGN 76 Query: 80 GVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIH 139 VT GD V P Q+G++ Sbjct: 77 EVTMFNQGDIVYYSGSPD---------------------------QNGSN---------- 99 Query: 140 HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT------PG 193 ++Y +++E VAK E+ + T Y + +V ++ G Sbjct: 100 --------AEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFGISRNRNENEG 151 Query: 194 STCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 T + G GGVG A KA G R+I + K++GA +N ++ Sbjct: 152 KTLLIINGAGGVGSIATQIAKAYG-LRVITTASRNETIEWTKKMGADIVLNHKE 204 >4A27-A nrPDB Length = 349 Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Query: 32 PKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGHEAAGIVESVGEGVTTVKPGDK 89 P+ E++I++ A G+ D V G + P P++ G E +GIVE++G+ V + GD+ Sbjct: 28 PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 87 Query: 90 VIPLAIPQCGKCRICKNPESNYCLKNDVS 118 V+ +C E Y + +D+S Sbjct: 88 VMAFVNYNAWAEVVCTPVEFVYKIPDDMS 116 >4RVS-A nrPDB Length = 329 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Query: 32 PKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGV----TTVKPG 87 P E+ IK A+G+ D + SG LP ++G E G VE+VG GV T + G Sbjct: 26 PGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVG 85 Query: 88 DKVIPLAIPQCGKCRICKNPES 109 D+V+ A C P S Sbjct: 86 DRVVS-ASANGAYAEFCTAPAS 106 >4Y1B-A nrPDB Length = 425 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 83/386 (21%), Positives = 148/386 (38%), Gaps = 71/386 (18%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVIL--------------G 67 F E V+V P +V +K++A G+ + V + PL VI G Sbjct: 58 FRTEVVDVPPVGPGQVLVKVMAAGVNYNN---VWAALGEPLDVIAARQKQGATEDFHIGG 114 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 + +GIV +VG+GV +KPG +V+ LA C+ ES D+ + Sbjct: 115 SDLSGIVWAVGDGV-RLKPGAEVVVLA---------CRWDES----AQDIRLGADPVTSS 160 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAV-AKIDAASPLEKVCLIGCGFSTGYGSAVN 186 T R + +F+Q+ VVDE K S C + +T Y Sbjct: 161 TQRVWGYEE------NYGSFAQFAVVDEYMCHPKPQRLSWAAASCYMATA-ATAYRQLFG 213 Query: 187 VA--KVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 V PG ++ G GG+G AI + G +AV ++++ LGA I+ Sbjct: 214 WEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGI-PVAVVSSEERGEFCMRLGAKGWID 272 Query: 244 PQDYKK-------PIQEVLKEMTDGGVDFS---FEVIGR------------LDTMMASLL 281 +++ +E +K+ DG F +EV+G DT+ S+ Sbjct: 273 RREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLGERRAPRIVLEHSGADTIPTSIY 332 Query: 282 CCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKF 341 A + G + ++ + + + R +G+ + + +L+ + Sbjct: 333 MADNAGMVVICGGTTGYNGDVDLRFLWMRQKRL-QGSHAASAREAREITRLI-----DQG 386 Query: 342 SLDALITHVLPFEKINEGFDLLHSGK 367 ++D ++ FE+I L+H + Sbjct: 387 AIDPCLSRTFGFEEIGLAHQLIHDNQ 412 >4DVJ-A nrPDB Length = 363 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 61/249 (24%), Positives = 94/249 (37%), Gaps = 67/249 (26%) Query: 32 PKAHEVRIKMVAVGICGTDDHVVSGTMV--TPLPVILGHEAAGIVESVGEGVTTVKPGDK 89 P H++ +++ AV + D V T T VI G++AAGIV +VG VT +PGD+ Sbjct: 50 PAGHDILVEVKAVSVNPVDYKVRRSTPPDGTDWKVI-GYDAAGIVSAVGPDVTLFRPGDE 108 Query: 90 VIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQ 149 V G ++ GT+ ++ Sbjct: 109 VF-----YAGSI----------------------IRPGTN------------------AE 123 Query: 150 YTVVDENAVAK----ID----AASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-- 199 + +VDE V + +D AA PL + F ++V K PG+ A+ Sbjct: 124 FHLVDERIVGRKPKTLDWAEAAALPLTSITAWEAFFDR-----LDVNKPVPGAAPAILIV 178 Query: 200 -GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEM 258 G GGVG A+ + +IA + K LGA I D+ KP+ + + Sbjct: 179 GGAGGVGSIAVQIARQRTDLTVIATASRPETQEWVKSLGAHHVI---DHSKPLAAEVAAL 235 Query: 259 TDGGVDFSF 267 G F F Sbjct: 236 GLGAPAFVF 244 >2WEK-A nrPDB Length = 341 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 8/133 (6%) Query: 141 FLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFG 200 ++ +F++YTVV + + + P E + L+ G +T Y S + ++ G V Sbjct: 93 YMAPGSFAEYTVVPASIATPVPSVKP-EYLTLLVSG-TTAYISLKELGGLSEGKKVLVTA 150 Query: 201 L-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK-KPIQEVLKEM 258 GG G A+ K A +I + +K A K LG C P +YK +P+ VLK+ Sbjct: 151 AAGGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLG---CDRPINYKTEPVGTVLKQE 206 Query: 259 TDGGVDFSFEVIG 271 GVD +E +G Sbjct: 207 YPEGVDVVYESVG 219 >6C49-A nrPDB Length = 350 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 5/100 (5%) Query: 21 PFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILGHEAAGIVESVGE 79 P+ + E+ P H+V +K+ G+C +D V++ T PV+ GHE G + ++G Sbjct: 28 PYKFDAGELQP---HQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHEIIGRIVALGS 84 Query: 80 GVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVS 118 ++ G +V I C C C + C +++ Sbjct: 85 EAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIA 124 >3HZZ-A nrPDB Length = 467 Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust. Identities = 68/313 (21%), Positives = 117/313 (37%), Gaps = 66/313 (21%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTL 124 I+G + AG+V G GV +PGD+V+ +CL ++ +P G Sbjct: 138 IIGSDLAGVVLRTGPGVNAWQPGDEVVA------------------HCLSVELESPDG-- 177 Query: 125 QDGTSRFTCRRKPIHHFLGIST----FSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 D T P G T ++ +V N + E+ G ST Sbjct: 178 HDDTM-----LDPEQRIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTA 232 Query: 181 YGSAV--NVAKVTPGSTCAVFGL-GGVGLSAIMG--------------------CKAAGA 217 Y V N A + G ++G GG+G A C++ GA Sbjct: 233 YRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSPQKAEICRSMGA 292 Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTM 276 II + KF K + +P+++K+ + ++E+T G +D FE GR +T Sbjct: 293 EAIIDRNAEGYKFWKDE-----HTQDPKEWKR-FGKRIRELTGGEDIDIVFEHPGR-ETF 345 Query: 277 MASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVAD- 335 AS+ + GT + N L ++ + G+ ++ +L+A Sbjct: 346 GASVYVTRKG-GTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAYEANRLIAKG 404 Query: 336 ----FMAKKFSLD 344 ++K +SL+ Sbjct: 405 KIHPTLSKTYSLE 417 >4IDE-A nrPDB Length = 332 Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust. Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Query: 33 KAHEVRIKMVAVGICGTDDHVVSGTMV---TPLPVILGHEAAGIVESVGEGVTTVKPGDK 89 K +V IK+VA + D G +PLP I G++ AG+V VG VT K GD+ Sbjct: 51 KEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVTKFKVGDE 110 Query: 90 V 90 V Sbjct: 111 V 111 >3TQH-A nrPDB Length = 321 Score = 35.4 bits (80), Expect = 0.040, Method: Compositional matrix adjust. Identities = 61/248 (24%), Positives = 92/248 (37%), Gaps = 66/248 (26%) Query: 54 VSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLA----IPQCGKCRICKNPES 109 V+ + LP LG++ +G V +G V V GDKV+ +A P C +C +P++ Sbjct: 59 VAKKLKNNLPSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPCCYAEYVCASPDT 118 Query: 110 NYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEK 169 + K++ S L+ Sbjct: 119 -----------------------------------------------IIQKLEKLSFLQA 131 Query: 170 VCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKD 228 L G + A+N A+V G + G GGVG AI K G I Sbjct: 132 ASLPTAGLTAL--QALNQAEVKQGDVVLIHAGAGGVGHLAIQLAKQKGTTVITTASKRNH 189 Query: 229 KFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACG 288 F KA LGA +CIN + ++ L ++ VD +++G D + S+ C E Sbjct: 190 AFLKA--LGAEQCINYHE-----EDFLLAIST-PVDAVIDLVGG-DVGIQSIDCLKE--- 237 Query: 289 TSVIVGVP 296 T IV VP Sbjct: 238 TGCIVSVP 245 >5A3V-A nrPDB Length = 329 Score = 35.0 bits (79), Expect = 0.047, Method: Compositional matrix adjust. Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 6/71 (8%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL-----PVILGHEAAGIVESVGEG 80 +V V PK++EV +K+ A + D + G M+ P P I + AG V VG G Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKG-MIRPFLPRKFPCIPATDVAGEVVEVGSG 83 Query: 81 VTTVKPGDKVI 91 V K GDKV+ Sbjct: 84 VKNFKAGDKVV 94 >2VWH-A nrPDB Length = 357 Score = 34.3 bits (77), Expect = 0.087, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 8/66 (12%) Query: 32 PKAHEVRIKMVAVGICGTDDHVVSGTMVTPLP-----VILGHEAAGIVESVGEGVTTVKP 86 P++ E ++ + VG+ GTD V++G P ++LGHEA G+V V T ++ Sbjct: 23 PESGEALVRTLRVGVDGTDHEVIAGGH-GGFPEGEDHLVLGHEAVGVV--VDPNDTELEE 79 Query: 87 GDKVIP 92 GD V+P Sbjct: 80 GDIVVP 85 >2OBY-A nrPDB Length = 338 Score = 34.3 bits (77), Expect = 0.099, Method: Compositional matrix adjust. Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 7/127 (5%) Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206 +QY V E + I L + I + T + V V G + GL GVG Sbjct: 102 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 161 Query: 207 SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264 +AI + AGA ++ K K A++LGA N YKK + LK GV+ Sbjct: 162 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 217 Query: 265 FSFEVIG 271 + IG Sbjct: 218 LILDCIG 224 >4J6F-A nrPDB Length = 382 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 17/91 (18%) Query: 18 LKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP---------------- 61 L+K +V V P A EV IK+ A G+ TD V G T Sbjct: 45 LEKLVYSRDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTL 104 Query: 62 -LPVILGHEAAGIVESVGEGVTTVKPGDKVI 91 P I G + G + +VGEGV + G++V+ Sbjct: 105 TFPRIQGTDTVGHIVAVGEGVDRARIGERVM 135 >6HRH-B nrPDB Length = 469 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 5/92 (5%) Query: 144 ISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 IS S++ V E +A++ + L F + +AK+ PG C ++ G Sbjct: 111 ISGTSKFHVELEQELAELHQK---DSALLFSSCFVANDSTLFTLAKILPG--CEIYSDAG 165 Query: 204 VGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 S I G + +GAA+ + + D K E Sbjct: 166 NHASMIQGIRNSGAAKFVFRHNDPDHLKKLLE 197 >4KPA-A nrPDB Length = 494 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 22/42 (52%) Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 KP+Q ++K + G F FE GR+ ++S EAC S Sbjct: 48 KPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDES 89 >2CF5-A nrPDB Length = 357 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 84/350 (24%), Positives = 142/350 (40%), Gaps = 43/350 (12%) Query: 21 PFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILGHEAAGIVESVGE 79 P++ E P +V I+++ GIC TD H + ++ P++ GHE G V VG Sbjct: 24 PYTYTLRETGP---EDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGEVVEVGS 80 Query: 80 GVTTVKPGD-KVIPLAIPQCGKCRICKNPESNYCLK-----NDVSNPQGTLQDGTSRFTC 133 V+ GD + + CG C C+ YC K NDV Q G Sbjct: 81 DVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVYINGQPTQGG------ 134 Query: 134 RRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 193 F++ TVV + V KI +E+ + C T Y + PG Sbjct: 135 -------------FAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQPG 181 Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + GLGGVG + KA G + NK + ++LGA + + D K Sbjct: 182 LRGGILGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSDQAK---- 237 Query: 254 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGR 313 + E+ D +D+ + + + + L + G +++GV + + P+L+L + Sbjct: 238 -MSELAD-SLDYVIDTVP-VHHALEPYLSLLKLDGKLILMGVINNPLQF-LTPLLMLGRK 293 Query: 314 TWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 G+ +G K E + + K+ L ++I V+ + +N F+ L Sbjct: 294 VITGSFIGSMKETEEMLEF-----CKEKGLSSII-EVVKMDYVNTAFERL 337 >6ACF-A nrPDB Length = 367 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 G AV G+G V GA ++I DINK+ A+A E + ++P D Sbjct: 173 GKVVAVQGVGNVAYHLCRHLHEEGA-KLIVTDINKEAVARAVEEFGAKAVDPND 225 >2B25-A nrPDB Length = 336 Score = 28.5 bits (62), Expect = 5.0, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 24/51 (47%) Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 +++ + PG T G G G+S + R+I+ ++ KD AK+ Sbjct: 98 LSMMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK 148 >1V9L-A nrPDB Length = 421 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 7/63 (11%) Query: 177 FSTGYGSAVNVAKVT-------PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDK 229 ++TG+G AV ++ G T A+ G+G VG + GA I DIN Sbjct: 187 YATGFGVAVATREMAKKLWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVA 246 Query: 230 FAK 232 + K Sbjct: 247 YRK 249 >5ILO-A nrPDB Length = 271 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 12/82 (14%) Query: 200 GLGGVGLSAIMGCKAAGAARIIAVDI--NKDKFAKAKELGATECI--------NPQDYKK 249 G GG+GL AAGAA++ +D+ N ++F K + T+ + N + + Sbjct: 23 GAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEA 82 Query: 250 PIQEVLKEMTDGGVDFSFEVIG 271 +E+ K T G +D V G Sbjct: 83 TYEEIAK--TFGNIDIVVNVAG 102 >2VN8-A nrPDB Length = 375 Score = 28.1 bits (61), Expect = 6.9, Method: Compositional matrix adjust. Identities = 79/320 (24%), Positives = 110/320 (34%), Gaps = 76/320 (23%) Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 P+ LG + +G+V G V KPGD+V A+P Q Sbjct: 94 FPLTLGRDVSGVVMECGLDVKYFKPGDEVWA-AVPPW---------------------KQ 131 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKI------DAASPLEKVCLIGC 175 GTL S++ VV N V+ A+ L V L Sbjct: 132 GTL-----------------------SEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAW 168 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 G +N T + GGVG AI KA A + AV ++D ++ Sbjct: 169 SAINKVG-GLNDKNCTGKRVLILGASGGVGTFAIQVMKAWD-AHVTAV-CSQDASELVRK 225 Query: 236 LGATECINPQDYKK-PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 LGA + I DYK ++E LK + DF + +G A + T V + Sbjct: 226 LGADDVI---DYKSGSVEEQLKSLKP--FDFILDNVGGSTETWAPDFLKKWSGATYVTLV 280 Query: 295 VP--PDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDAL------ 346 P + L + +L TG T L F + V A FMA LD + Sbjct: 281 TPFLLNMDRLGIADGMLQTGVTVGSKALKHF--WKGVHYRWAFFMASGPCLDDIAELVDA 338 Query: 347 ------ITHVLPFEKINEGF 360 I PF K+ E F Sbjct: 339 GKIRPVIEQTFPFSKVPEAF 358 >1V3V-A nrPDB Length = 333 Score = 27.7 bits (60), Expect = 7.7, Method: Compositional matrix adjust. Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 19/118 (16%) Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAIMGCKAAGAARIIAVDIN 226 IG T Y + V V G T V G VG ++ + GCK GAA + Sbjct: 126 IGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIAKLKGCKVVGAAG------S 179 Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG--RLDTMMASL 280 +K A K++G N YK ++E LK+ + G D F+ +G L+T+++ + Sbjct: 180 DEKIAYLKQIGFDAAFN---YKTVNSLEEALKKASPDGYDCYFDNVGGEFLNTVLSQM 234 >4A10-A nrPDB Length = 447 Score = 27.7 bits (60), Expect = 9.1, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 17/27 (62%) Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVI 91 +LG + +G+V G GV KPGD VI Sbjct: 112 VLGSDCSGVVVRTGIGVRRWKPGDHVI 138 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1HSO-A nrPDB 500 e-142 1HSZ-A nrPDB 494 e-140 1U3W-A nrPDB 489 e-139 1EE2-A nrPDB 464 e-131 3COS-A nrPDB 434 e-122 1D1T-A nrPDB 433 e-122 1MC5-A nrPDB 425 e-119 4DLA-A nrPDB 419 e-118 1CDO-A nrPDB 416 e-117 4JJI-A nrPDB 416 e-116 1E3E-A nrPDB 409 e-114 4RQU-A nrPDB 406 e-114 1P0F-A nrPDB 394 e-110 3PII-A nrPDB 304 4e-83 5TNX-A nrPDB 297 7e-81 1F8F-A nrPDB 296 9e-81 3MEQ-A nrPDB 295 3e-80 4Z6K-A nrPDB 287 4e-78 1LLU-A nrPDB 283 9e-77 3S2F-A nrPDB 281 4e-76 2DFV-A nrPDB 280 7e-76 2EER-A nrPDB 271 3e-73 3GFB-A nrPDB 270 6e-73 1PL8-A nrPDB 266 1e-71 6N7L-A nrPDB 264 4e-71 3QE3-A nrPDB 264 5e-71 2DQ4-A nrPDB 259 2e-69 4CPD-A nrPDB 256 1e-68 5KIA-A nrPDB 251 3e-67 1R37-A nrPDB 248 3e-66 4EEZ-A nrPDB 248 4e-66 5YLN-A nrPDB 245 3e-65 1H2B-A nrPDB 244 4e-65 5VM2-A nrPDB 243 7e-65 5ENV-A nrPDB 241 4e-64 1YKF-A nrPDB 240 8e-64 1UUF-A nrPDB 236 9e-63 4EJ6-A nrPDB 236 9e-63 5H82-A nrPDB 236 2e-62 3FSR-A nrPDB 234 4e-62 1E3J-A nrPDB 234 6e-62 3FPC-A nrPDB 231 5e-61 3FPL-A nrPDB 229 1e-60 5YAT-A nrPDB 227 6e-60 1KEV-A nrPDB 224 6e-59 4OAQ-A nrPDB 223 1e-58 4GKV-A nrPDB 222 2e-58 5K1S-A nrPDB 221 4e-58 3TWO-A nrPDB 219 2e-57 1YQX-A nrPDB 218 3e-57 4OH1-A nrPDB 218 4e-57 3M6I-A nrPDB 217 6e-57 5Z0C-A nrPDB 217 6e-57 2H6E-A nrPDB 214 6e-56 4ILK-A nrPDB 209 1e-54 4UEJ-A nrPDB 208 4e-54 3IP1-A nrPDB 208 4e-54 2OUI-A nrPDB 206 2e-53 6FG0-A nrPDB 205 2e-53 5FI5-A nrPDB 204 6e-53 6DKH-A nrPDB 201 3e-52 1YB5-A nrPDB 200 8e-52 5VKT-A nrPDB 193 2e-49 5H83-A nrPDB 192 2e-49 3UOG-A nrPDB 187 9e-48 1Q1N-A nrPDB 179 1e-45 4Y1B-A nrPDB 178 3e-45 2DPH-A nrPDB 177 6e-45 3QWB-A nrPDB 171 3e-43 3WLE-A nrPDB 171 5e-43 1WLY-A nrPDB 170 1e-42 4JLW-A nrPDB 170 1e-42 1KOL-A nrPDB 159 1e-39 3B70-A nrPDB 151 5e-37 3FBG-A nrPDB 150 8e-37 2VCY-A nrPDB 150 9e-37 4RVS-A nrPDB 150 1e-36 1QOR-A nrPDB 145 3e-35 3JYN-A nrPDB 135 3e-32 4A27-A nrPDB 123 1e-28 3SLK-A nrPDB 122 2e-28 2CDC-A nrPDB 103 1e-22 3WID-A nrPDB 96 2e-20 Sequences not found previously or not previously below threshold: 6C49-A nrPDB 162 3e-40 2CF5-A nrPDB 151 7e-37 3HZZ-A nrPDB 144 4e-35 2OBY-A nrPDB 134 4e-32 4J6F-A nrPDB 129 2e-30 4A10-A nrPDB 128 4e-30 3TQH-A nrPDB 121 4e-28 4IDE-A nrPDB 116 2e-26 2VN8-A nrPDB 116 2e-26 4DVJ-A nrPDB 115 3e-26 5A3V-A nrPDB 110 1e-24 2WEK-A nrPDB 110 1e-24 4EYE-A nrPDB 104 1e-22 2VWH-A nrPDB 99 4e-21 5LB9-A nrPDB 82 5e-16 1V3V-A nrPDB 80 2e-15 5GXF-A nrPDB 77 2e-14 2Y05-A nrPDB 73 2e-13 1O89-A nrPDB 71 1e-12 2J3K-A nrPDB 62 3e-10 2VNA-A nrPDB 58 6e-09 2ZB3-A nrPDB 54 1e-07 1ZCJ-A nrPDB 44 9e-05 3ZWA-A nrPDB 43 2e-04 4DIO-A nrPDB 42 4e-04 5ILO-A nrPDB 42 5e-04 2EGU-A nrPDB 41 0.001 3MGG-A nrPDB 40 0.001 1X14-A nrPDB 40 0.002 2B25-A nrPDB 39 0.003 2VHY-A nrPDB 38 0.006 1XLT-A nrPDB 38 0.006 3X2F-A nrPDB 37 0.016 6BII-A nrPDB 36 0.021 5JE5-A nrPDB 36 0.025 5EKU-A nrPDB 36 0.029 4M36-A nrPDB 36 0.029 6ACF-A nrPDB 36 0.031 1VH3-A nrPDB 36 0.034 4XIJ-A nrPDB 35 0.035 5VMT-A nrPDB 35 0.036 5X7F-A nrPDB 35 0.054 1W1U-A nrPDB 35 0.060 4K2X-A nrPDB 35 0.061 1BW9-B nrPDB 35 0.069 1V8B-A nrPDB 35 0.069 5Z1Z-A nrPDB 35 0.076 1V9L-A nrPDB 34 0.091 3D2L-A nrPDB 34 0.11 3VPX-A nrPDB 34 0.12 4COO-A nrPDB 34 0.13 4CUK-A nrPDB 34 0.13 1DXY-A nrPDB 34 0.14 1M54-A nrPDB 34 0.14 5MMS-A nrPDB 34 0.15 5F8E-A nrPDB 34 0.16 2YVG-A nrPDB 34 0.16 4N7R-A nrPDB 34 0.16 1EUF-A nrPDB 34 0.17 2ZJ1-A nrPDB 33 0.19 4AEC-A nrPDB 33 0.20 6GME-A nrPDB 33 0.22 3EGI-A nrPDB 33 0.22 3GDH-A nrPDB 33 0.22 5JXW-A nrPDB 33 0.22 4OM8-A nrPDB 33 0.22 1JWB-B nrPDB 33 0.22 2O23-A nrPDB 33 0.24 2EKL-A nrPDB 33 0.26 1E3W-A nrPDB 33 0.28 6C55-A nrPDB 33 0.29 6IQV-A nrPDB 32 0.34 2ISQ-A nrPDB 32 0.35 5AOV-A nrPDB 32 0.36 3KYD-B nrPDB 32 0.37 3KYC-B nrPDB 32 0.37 2EEZ-A nrPDB 32 0.38 5MH6-A nrPDB 32 0.40 6BQ5-A nrPDB 32 0.41 1CYD-A nrPDB 32 0.42 3D3W-A nrPDB 32 0.44 6FZI-A nrPDB 32 0.46 1XDW-A nrPDB 32 0.47 3G1U-A nrPDB 32 0.48 4FS8-A nrPDB 32 0.48 5UYY-A nrPDB 32 0.50 1I9G-A nrPDB 32 0.53 5D84-A nrPDB 32 0.55 1ZFN-A nrPDB 32 0.57 4DIB-A nrPDB 32 0.60 5M0P-A nrPDB 32 0.61 3OAM-A nrPDB 31 0.69 4XGI-A nrPDB 31 0.73 5U9P-A nrPDB 31 0.77 5JJC-A nrPDB 31 0.79 3AOE-A nrPDB 31 0.81 1GPJ-A nrPDB 31 0.94 1W7I-A nrPDB 31 0.98 2HMT-A nrPDB 31 0.98 4WJI-A nrPDB 31 1.0 4PZE-A nrPDB 31 1.0 5BUT-A nrPDB 31 1.0 5FUB-A nrPDB 31 1.1 4MOP-A nrPDB 30 1.1 4K28-A nrPDB 30 1.2 5UJU-A nrPDB 30 1.3 6DLL-A nrPDB 30 1.3 1QO8-A nrPDB 30 1.3 6J0Z-C nrPDB 30 1.3 3F9I-A nrPDB 30 1.5 5NMX-A nrPDB 30 1.5 3BKX-A nrPDB 30 1.5 4YRY-B nrPDB 30 1.5 3EMK-A nrPDB 30 1.6 4RS3-A nrPDB 30 1.6 2WMH-A nrPDB 30 1.7 1NVM-B nrPDB 30 1.7 5OHX-A nrPDB 30 1.7 3NJ4-A nrPDB 30 1.7 2AS0-A nrPDB 30 1.8 6GBN-A nrPDB 30 1.8 3HM2-A nrPDB 30 1.8 1VE9-A nrPDB 30 1.8 3FBT-A nrPDB 30 1.9 2EFY-A nrPDB 30 2.0 1DOD-A nrPDB 30 2.1 2BRY-A nrPDB 30 2.1 4TXK-A nrPDB 30 2.2 4J90-A nrPDB 30 2.2 1LTH-T nrPDB 30 2.2 3X43-A nrPDB 30 2.3 4XWI-A nrPDB 30 2.3 5TQV-A nrPDB 30 2.4 3DC2-A nrPDB 30 2.4 2WWR-A nrPDB 30 2.5 3ZZN-A nrPDB 29 2.5 3WGE-A nrPDB 29 2.5 6HNS-A nrPDB 29 2.6 3GDF-A nrPDB 29 2.6 1ZVF-A nrPDB 29 2.6 1FI8-A nrPDB 29 2.6 5ZBK-A nrPDB 29 2.7 5XJ2-A nrPDB 29 2.8 4LMA-A nrPDB 29 2.8 2E28-A nrPDB 29 2.9 1WG8-A nrPDB 29 2.9 1HL3-A nrPDB 29 2.9 3HDH-A nrPDB 29 3.0 3JTJ-A nrPDB 29 3.0 6APH-A nrPDB 29 3.1 3TNL-A nrPDB 29 3.1 3OC4-A nrPDB 29 3.2 5J9G-A nrPDB 29 3.2 3OJO-A nrPDB 29 3.2 4ZV2-A nrPDB 29 3.5 3OND-A nrPDB 29 3.6 6ABI-A nrPDB 29 3.7 4DIM-A nrPDB 29 3.7 1F14-A nrPDB 29 3.7 3JTM-A nrPDB 29 3.7 5VJ7-A nrPDB 29 4.0 3H9U-A nrPDB 29 4.2 4P8R-A nrPDB 29 4.3 5B37-A nrPDB 29 4.5 3LLV-A nrPDB 29 4.6 3LP6-A nrPDB 29 4.7 1G6Q-1 nrPDB 29 4.7 2RIR-A nrPDB 29 4.7 4IZO-A nrPDB 29 4.8 1AHH-A nrPDB 29 4.8 3DOC-A nrPDB 29 4.8 1WY7-A nrPDB 29 5.1 3HWR-A nrPDB 29 5.3 1YPF-A nrPDB 29 5.4 2QHR-L nrPDB 29 5.4 2X36-A nrPDB 29 5.5 1V9C-A nrPDB 29 5.5 5J46-A nrPDB 28 5.6 2GMH-A nrPDB 28 5.7 5JFC-L nrPDB 28 6.0 4GCM-A nrPDB 28 6.0 3NNK-A nrPDB 28 6.1 3T4P-A nrPDB 28 6.2 1LSS-A nrPDB 28 6.2 4P4L-A nrPDB 28 6.5 3RHA-A nrPDB 28 6.7 3GG9-A nrPDB 28 7.2 4FHN-X nrPDB 28 7.3 4F86-A nrPDB 28 7.3 4KIC-A nrPDB 28 7.5 1S4D-A nrPDB 28 7.9 3AOE-E nrPDB 28 8.4 3T5Y-A nrPDB 28 8.5 3PPI-A nrPDB 28 8.5 4DZR-A nrPDB 28 8.9 3A26-A nrPDB 28 8.9 1MV8-A nrPDB 28 9.4 >1HSO-A nrPDB Length = 374 Score = 500 bits (1287), Expect = e-142, Method: Composition-based stats. Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 120 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTILMF 375 LLHSGKSIRTILMF Sbjct: 361 LLHSGKSIRTILMF 374 >1HSZ-A nrPDB Length = 374 Score = 494 bits (1272), Expect = e-140, Method: Composition-based stats. Identities = 350/374 (93%), Positives = 362/374 (96%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVAVGIC TDDHVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCR+CKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTCR KPIHHFLG STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAVNVAKVTPGSTCAVFGLGGVGLSA+MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQN 300 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLLTGRTWKGA+ GGFKSKE +PKLVADFMAKKFSLDALITHVLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTILMF 375 LLHSGKSIRT+L F Sbjct: 361 LLHSGKSIRTVLTF 374 >1U3W-A nrPDB Length = 374 Score = 489 bits (1260), Expect = e-139, Method: Composition-based stats. Identities = 347/374 (92%), Positives = 359/374 (95%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVA GIC +D+HVVSG +VTP Sbjct: 1 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPL PQCGKCRICKNPESNYCLKND+ NP+ Sbjct: 61 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPR 120 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GTLQDGT RFTC KPIHHF+G+STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY Sbjct: 121 GTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 180 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVTPGSTCAVFGLGGVGLS +MGCKAAGAARIIAVDINKDKFAKAKELGATEC Sbjct: 181 GSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATEC 240 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 INPQDYKKPIQEVLKEMTDGGVDFSFEVIG+LDTMMASLLCCHEACGTSVIVGVPPDSQN Sbjct: 241 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQN 300 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LS+NPMLLLTGRTWKGAI GGFKSKE VPKLVADFMAKKFSLDALIT+VLPFEKINEGFD Sbjct: 301 LSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFD 360 Query: 362 LLHSGKSIRTILMF 375 LL SGKSIRT+L F Sbjct: 361 LLRSGKSIRTVLTF 374 >1EE2-A nrPDB Length = 373 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 326/374 (87%), Positives = 346/374 (92%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 STAGKVIKCKAAVLWE KKPFSIEEVEVAPPKAHEVRIKMVA GIC +DDHVVSGT+V P Sbjct: 1 STAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPVI GHEAAGIVES+GEGVTTV+PGDKVIPL IPQCGKC +CK+PE N CLKN +S P+ Sbjct: 61 LPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKN-LSMPR 119 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 GT+QDGTSRFTCR KPIHHFLG STFSQYTVVDE +VAKIDAASPLEKVCL+GCGFSTGY Sbjct: 120 GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY 179 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 GSAV VAKVT GSTCAVFGLGGVGLS IMGCKAAGAARII VDINKDKFAKAKE+GATEC Sbjct: 180 GSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 +NPQDYKKPIQEVL EM++GGVDFSFEVIGRLDTM+A+L CC EA G SVIVGVPPDSQN Sbjct: 240 VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQN 299 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 LSMNPMLLL+GRTWKGAI GGFKSK+ VPKLVADFMAKKF+LD LITHVLPFEKINEGFD Sbjct: 300 LSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD 359 Query: 362 LLHSGKSIRTILMF 375 LL SGKSIRTIL F Sbjct: 360 LLRSGKSIRTILTF 373 >3COS-A nrPDB Length = 381 Score = 434 bits (1115), Expect = e-122, Method: Composition-based stats. Identities = 227/380 (59%), Positives = 280/380 (73%), Gaps = 5/380 (1%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-V 59 M T GKVIKCKAA+ WE KP IEEVEVAPPKAHEVRI+++A +C TD V+ Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 60 TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSN 119 PVI+GHEAAGIVES+G GVT VKPGDKVIPL P C KC+ C +P +N C K Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 120 PQG----TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 ++D TSRFTC+ KP++HF G STFSQYTVV + +AKID + LE+VCL+GC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 GFSTGYG+A+N AKVTPGSTCAVFGLGGVGLSA+MGCKAAGA+RII +DIN +KF KAK Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 LGAT+C+NP+D KPIQEV+ E+T GGVDF+ + G +TM A+L C G+ +GV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 296 PPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEK 355 S+ L++ P L+ GRT G GG+KS + +PKLV D+ KKF+LDAL+TH LPF+K Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 356 INEGFDLLHSGKSIRTILMF 375 I+E FDL++ GKSIRTIL+F Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1D1T-A nrPDB Length = 373 Score = 433 bits (1113), Expect = e-122, Method: Composition-based stats. Identities = 257/374 (68%), Positives = 311/374 (83%), Gaps = 1/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GIC TDDHV+ GTMV+ Sbjct: 1 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 PVI+GHEA GIVES+GEGVTTVKPGDKVIPL +PQC +C C+NP+ N C+++D+ + Sbjct: 61 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDI-TGR 119 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGY 181 G L DGT+RFTC+ KP+HHFL STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGY Sbjct: 120 GVLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGY 179 Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G+AV KV PGSTC VFGLGGVGLS IMGCK+AGA+RII +D+NKDKF KA +GATEC Sbjct: 180 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 239 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 I+P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ Sbjct: 240 ISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKM 299 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 L+ +PMLL TGRTWKG + GG KS++ VPKLV +F+AKKF LD LITHVLPF+KI+EGF+ Sbjct: 300 LTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 359 Query: 362 LLHSGKSIRTILMF 375 LL+SG+SIRT+L F Sbjct: 360 LLNSGQSIRTVLTF 373 >1MC5-A nrPDB Length = 374 Score = 425 bits (1092), Expect = e-119, Method: Composition-based stats. Identities = 237/371 (63%), Positives = 290/371 (78%), Gaps = 1/371 (0%) Query: 4 AGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP-L 62 A +VIKCKAAV WE KP SIEE+EVAPPKAHEVRIK++A +C TD + +SG Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQG 122 PVILGHE AGIVESVGEGVT +K GD VIPL IPQCG+C+ C NP++N C K V+ +G Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121 Query: 123 TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + DGTSRFTC+ K I H++G STFS+YTVV + +VAKID +PL+KVCL+GCG STGYG Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181 Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 +AVN AK+ PGS CAVFGLGGVGL+ IMGCK AGA+RII VDINKDKFA+AKE GATECI Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 NPQD+ KPIQEVL EMTDGGVD+SFE IG + M A+L CH+ G SV+VGV + + Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301 Query: 303 SMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 + P L+TGRTWKG GG+KS E VPKLV+++M+KK +D +TH L F++IN+ F+L Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361 Query: 363 LHSGKSIRTIL 373 +HSGKSIRT++ Sbjct: 362 MHSGKSIRTVV 372 >4DLA-A nrPDB Length = 396 Score = 419 bits (1078), Expect = e-118, Method: Composition-based stats. Identities = 199/374 (53%), Positives = 258/374 (68%), Gaps = 2/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 +T G+VI CKAAV WE KP IE+V+VAPP+A EVR+K++ +C TD + SG Sbjct: 19 ATQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEG 78 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 L P +LGHEAAGIVESVGEGVT V+PGD VIP +C +C+ CK+ ++N C K + Sbjct: 79 LFPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATG 138 Query: 121 QG-TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D SRF+ KPI+HF+G STFSQYTVV + +VAKID +PLEKVCL+GCG T Sbjct: 139 VGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPT 198 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS AVFGLG VGL+ G KAAGA+RII +DI+ KF +AK G T Sbjct: 199 GLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVT 258 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E INP+++++PIQ+V+ ++TDGGVD+SFE IG + M ++L CCH+ GTSVIVGV Sbjct: 259 EFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASG 318 Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG GGFKS+ VP LV ++ K+ +D ITH + IN+ Sbjct: 319 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKA 378 Query: 360 FDLLHSGKSIRTIL 373 FDL+H G +R +L Sbjct: 379 FDLMHDGDCLRVVL 392 >1CDO-A nrPDB Length = 374 Score = 416 bits (1069), Expect = e-117, Method: Composition-based stats. Identities = 206/375 (54%), Positives = 269/375 (71%), Gaps = 2/375 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDD-HVVSGTMVT 60 +T GKVIKCKAAV WE KP IEE+EV P A+E+RIK++A G+C TD H+ G Sbjct: 1 ATVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 PV+LGHE AGIVESVG GVT +PG+KVIPL I QCG+CR C++P++N C+K + Sbjct: 61 GFPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANES 120 Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 + +RFTC+ + + FLG STFSQYTVV++ AVAKID ++PL+ VCL+GCG STG Sbjct: 121 PDVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTG 180 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 +G+AVN AKV PGSTCAVFGLG VGL+A+MGC +AGA RIIAVD+N DKF KAK GAT+ Sbjct: 181 FGAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATD 240 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 +NP D+ +PI +VL +MT+GGVDFS E +G + M +L C + G SV+VG D Sbjct: 241 FVNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWT-DLH 299 Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 +++ P+ L+ GRTWKG++ GGFK K+ VPK+V ++ KK LD ITH +P E +N+ Sbjct: 300 DVATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAI 359 Query: 361 DLLHSGKSIRTILMF 375 DL+ GK IRT+L Sbjct: 360 DLMKHGKCIRTVLSL 374 >4JJI-A nrPDB Length = 378 Score = 416 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 200/374 (53%), Positives = 255/374 (68%), Gaps = 2/374 (0%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 +T G+VI CKAAV +E KP IE+V+VAPP+A EVRIK++ +C TD + SG Sbjct: 1 ATQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEG 60 Query: 62 L-PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 L P ILGHEAAGIVESVGEGVT V+ GD VIP +C +C+ CK+ ++N C K + Sbjct: 61 LFPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATG 120 Query: 121 QG-TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179 G + D SRF+ KPI+HF+G STFSQYTVV + +VAKID +PL+KVCL+GCG T Sbjct: 121 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 180 Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 G G+ N AKV PGS A+FGLG VGL+ G K AGA+RII +DI+ K+ AK+ G Sbjct: 181 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 240 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 E +NP+D+ KPIQEV+ ++TDGGVD+SFE IG + M A+L CCH+ GTSVIVGV Sbjct: 241 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 300 Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359 Q +S P L+TGR WKG GGFKS+ VP LV +M K+ +D ITH L +IN+ Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 360 Query: 360 FDLLHSGKSIRTIL 373 FDLLH G +R +L Sbjct: 361 FDLLHEGTCLRCVL 374 >1E3E-A nrPDB Length = 376 Score = 409 bits (1050), Expect = e-114, Method: Composition-based stats. Identities = 205/378 (54%), Positives = 266/378 (70%), Gaps = 6/378 (1%) Query: 2 STAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP 61 T GKVIKCKAA+ W+ P IEE+EV+PPKA EVRI+++A +C TD + Sbjct: 1 GTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKAL 60 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSN-- 119 PV+LGHE AGIVESVG GVT KPGDKVIP PQC +C++C +P +N C K Sbjct: 61 FPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYP 120 Query: 120 --PQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGF 177 Q ++D TSRFTC+ + I+HF+G+S+FSQYTVV E +A++D + LE+VCLIGCGF Sbjct: 121 TIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGF 180 Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 S+GYG+A+N AKVTPGSTCAVFGLG VGLSAI+GCK AGA+RIIA+DIN +KF KAK LG Sbjct: 181 SSGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALG 240 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 AT+C+NP++ KP+Q+V+ E+T GGVD+S + G T+ A++ C G+ +VG Sbjct: 241 ATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKV 300 Query: 298 DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKIN 357 D + ++L GR+ G GG+KS + VP LV+D+ KKF LD L+TH LPFE IN Sbjct: 301 DEMTIPTVDVIL--GRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIN 358 Query: 358 EGFDLLHSGKSIRTILMF 375 + DL+ GKSIRTIL F Sbjct: 359 DAIDLMKEGKSIRTILTF 376 >4RQU-A nrPDB Length = 375 Score = 406 bits (1043), Expect = e-114, Method: Composition-based stats. Identities = 187/372 (50%), Positives = 246/372 (66%), Gaps = 2/372 (0%) Query: 6 KVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL-PV 64 ++I+CKAAV WE KP IEEVEVAPP+ HEVRIK++ +C TD + TPL P Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTL 124 I GHEA GIVESVGEGVT ++PGD V+P+ +CG+CR C + ESN C ++ +G + Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 125 -QDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 DG SRF+ KPI+HFLG STFS+YTVV VAKI+ +PL+KVC++ CG STG G+ Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN 243 +NVAK G + A+FGLG VGL A G + AGA+RII VD N +F +AKE G TEC+N Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 P+D+ KPIQ+V+ EMTDGGVD S E G + M+ + C H+ G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 304 MNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL 363 +PM L RT KG G +K K +P +V +M K+ L+ ITH +PF +IN+ FD + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 364 HSGKSIRTILMF 375 G+SIR I+ Sbjct: 362 LKGESIRCIITM 373 >1P0F-A nrPDB Length = 373 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 222/375 (59%), Positives = 288/375 (76%), Gaps = 2/375 (0%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60 M TAGK I CKAAV WE KP S+E + VAPPKAHEVRIK++A GICG+D V+ + + Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 61 PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 PVILGHEA G+VES+G GVT VKPGDKVIPL +PQCG CR CK+ SN+C KND+ Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + D TSRFTCR KPI++ +G STF++YTVV + AVAKID +PLE CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 YG+AVN AKVTPGSTCAVFGLGGVG SAI+GCKAAGA+RII V +KDKF KA ELGATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 C+NP+DY KPI EV+ E T+GGVD++ E GR++TMM +L + G +V++G+ ++ Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360 L ++P+LLLTGR+ KG++ GGFK E V +LV D+M KK +++ L++ L ++IN+ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 361 DLLHSGKSIRTILMF 375 +LL SG+ +R+I+++ Sbjct: 359 ELLSSGQGVRSIMIY 373 >3PII-A nrPDB Length = 339 Score = 304 bits (778), Expect = 4e-83, Method: Composition-based stats. Identities = 115/369 (31%), Positives = 162/369 (43%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV--TPLPVILGH 68 KAAV+ + K+P I+EVE EV +++ A G+C TD H G LP+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E GIVE VG GVT +K GD+V IP CG C C + + C Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQK----------- 110 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + +++Y + V KI E+ I C T Y A+ V Sbjct: 111 ----------NAGYSVDGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-KALKV 159 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG A++G+GG G A+ KA G ++AVDI +K AKELGA +NP Sbjct: 160 TGAKPGEWVAIYGIGGFGHVAVQYAKAMG-LNVVAVDIGDEKLELAKELGADLVVNP--L 216 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 K+ + +KE GGV + V S G V+VG+PP+ + + Sbjct: 217 KEDAAKFMKEKV-GGVHAAV-VTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFDT 274 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G G+I+G K + + A+ K I V P EKINE FD + G+ Sbjct: 275 -VLNGIKIIGSIVGTRKDLQEALQFAAEGKVK------TIIEVQPLEKINEVFDRMLKGQ 327 Query: 368 -SIRTILMF 375 + R +L Sbjct: 328 INGRVVLTL 336 >5TNX-A nrPDB Length = 383 Score = 297 bits (759), Expect = 7e-81, Method: Composition-based stats. Identities = 127/360 (35%), Positives = 180/360 (50%), Gaps = 8/360 (2%) Query: 19 KKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVG 78 PFSIE + P+ EV +++VA G+C TD V PLP +LGHE AG+VE+VG Sbjct: 27 GAPFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVG 86 Query: 79 EGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTS--RFTCRRK 136 V T+ GD V+ L CG C C YC + N G DG + R Sbjct: 87 PNVKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEP 145 Query: 137 PIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTC 196 HF S+F+ Y + EN K+ +PLE + +GCG TG G+ +N V GS+ Sbjct: 146 LHDHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSF 205 Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 A FG G VG+SA+M + AGA IIAVDI + A A ELGAT IN ++ + + ++ Sbjct: 206 ASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIR 263 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN-PMLLLTGRTW 315 E+T GGVD++ E G + + GT +VG P + LLL G T Sbjct: 264 EITGGGVDYALESTGLPAVLSQGIDALGSR-GTMGVVGAPKLGTKAEFDVNSLLLGGHTI 322 Query: 316 KGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMF 375 +G + G + +P+LV + +F D L+ P E+IN+ SG +++ IL Sbjct: 323 RGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLV-KFYPLEQINQAAADSSSGITLKPILRL 381 >1F8F-A nrPDB Length = 371 Score = 296 bits (758), Expect = 9e-81, Method: Composition-based stats. Identities = 123/365 (33%), Positives = 188/365 (51%), Gaps = 8/365 (2%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAA 71 AAV F ++ +++ P+ EV +K+VA G+C TD V PLP +LGHE + Sbjct: 9 AAVTPCKGADFELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGS 68 Query: 72 GIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRF 131 GI+E++G VT ++ GD V+ L+ CGKC C YC + N G +G Sbjct: 69 GIIEAIGPNVTELQVGDHVV-LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHAL 127 Query: 132 TCRRKPI--HHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 + + HF S+F+ Y + EN K+ P+E + +GCG TG G+ +N K Sbjct: 128 CTHDQGVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALK 187 Query: 190 VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 VTP S+ +G G VGLSA++ K GA+ IIAVDI + + AK+LGAT IN + + Sbjct: 188 VTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSK-TQD 246 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN-PML 308 P+ +KE+TDGGV+F+ E G + + + G +VG P + L Sbjct: 247 PVA-AIKEITDGGVNFALESTGSPEILKQGVDALG-ILGKIAVVGAPQLGTTAQFDVNDL 304 Query: 309 LLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKS 368 LL G+T G + G K+ +P+LV + KF D L+ F++IN+ G + Sbjct: 305 LLGGKTILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQAAIDSRKGIT 363 Query: 369 IRTIL 373 ++ I+ Sbjct: 364 LKPII 368 >3MEQ-A nrPDB Length = 365 Score = 295 bits (754), Expect = 3e-80, Method: Composition-based stats. Identities = 104/369 (28%), Positives = 148/369 (40%), Gaps = 35/369 (9%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVIL 66 KAAV+ KP +I+EV + P ++++ + A G+C TD H G P I Sbjct: 25 TMKAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIP 84 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 GHE G V +VG GV VK GD+V IP CG CR C C + Sbjct: 85 GHEGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEE----------- 133 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + + F++Y V D N V + ++ + C T Y + Sbjct: 134 ----------QLNTGYSVNGGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGL 182 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 V PG + G+GG+G A+ +A G + AVDI+ K A+ LGAT +N + Sbjct: 183 KVTDTKPGDWVVISGIGGLGHMAVQYARAMG-LNVAAVDIDDRKLDLARRLGATVTVNAK 241 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN 305 P + KE TDGG +L GT + G+PP LS+ Sbjct: 242 TVADPAAYIRKE-TDGGAQGVLVTAVSPKAFEQALGMVAR-GGTVSLNGLPPGDFPLSIF 299 Query: 306 PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 M +L G T +G+I+G + AD K E IN FD + Sbjct: 300 NM-VLNGVTVRGSIVGTRLDLQESLDFAADGKVKA------TIQTGKLEDINAIFDDMRQ 352 Query: 366 GKSIRTILM 374 G I+M Sbjct: 353 GNIEGRIVM 361 >4Z6K-A nrPDB Length = 346 Score = 287 bits (735), Expect = 4e-78, Method: Composition-based stats. Identities = 108/369 (29%), Positives = 162/369 (43%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGH 68 KAAVL E + IEEV++ P A E+ +KM A G+C TD H V G P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E G++ +VGEGVT VK GD+V + CG C C C S Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNS--------- 112 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + +F++Y + + N V I + ++ + C T Y + + Sbjct: 113 ------------GYSVNGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKM 159 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G A+ A G + AVDI+ DK A AK+LGA +N ++ Sbjct: 160 TDTKPGDWVVISGIGGLGHMAVQYAIAMG-LNVAAVDIDDDKLAFAKKLGAKVTVNAKNT 218 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 P + + KE+ GG + V L GT V G+PP +S+ Sbjct: 219 -DPAEYLQKEI--GGAHGAL-VTAVSAKAFDQALSMLRRGGTLVCNGLPPGDFPVSIFDT 274 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G T +G+I+G + + MA + A +T P E IN+ F+ + GK Sbjct: 275 -VLNGITIRGSIVGTRLDLQE-----SLDMAAAGKVKATVT-AEPLENINDIFERMRQGK 327 Query: 368 -SIRTILMF 375 R ++ + Sbjct: 328 IEGRIVIDY 336 >1LLU-A nrPDB Length = 342 Score = 283 bits (724), Expect = 9e-77, Method: Composition-based stats. Identities = 98/369 (26%), Positives = 155/369 (42%), Gaps = 38/369 (10%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV--TPLPVIL 66 KAAV+ P IEEV+V P +V +K+ A G+C TD H G PLP I Sbjct: 6 TMKAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIP 65 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 GHE G V +VG GVT VK GD+V IP CG C C C + Sbjct: 66 GHEGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNT------- 118 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + +++Y + D N V + ++ I C T Y + Sbjct: 119 --------------GYSVNGGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-KGL 163 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 PG A+ G+GG+G A+ +A G + A+DI+ K A++LGA+ +N + Sbjct: 164 KQTNARPGQWVAISGIGGLGHVAVQYARAMG-LHVAAIDIDDAKLELARKLGASLTVNAR 222 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN 305 + P++ + +++ GG V ++ + GT +VG+PP + Sbjct: 223 Q-EDPVEAIQRDI--GGAHGVL-VTAVSNSAFGQAIGMARRGGTIALVGLPPGDFPTPIF 278 Query: 306 PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 + +L G G+I+G + A + + A I H + IN+ D + + Sbjct: 279 DV-VLKGLHIAGSIVGTRADLQEALDF-----AGEGLVKATI-HPGKLDDINQILDQMRA 331 Query: 366 GK-SIRTIL 373 G+ R +L Sbjct: 332 GQIEGRIVL 340 >3S2F-A nrPDB Length = 340 Score = 281 bits (718), Expect = 4e-76, Method: Composition-based stats. Identities = 101/369 (27%), Positives = 151/369 (40%), Gaps = 38/369 (10%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGH 68 KAAV+ P +I+EV V P +V++K+ A G+C TD H G LP I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E G V +VG GV+ VK GD+V +P CG C C C K + Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNT--------- 114 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + + +Y V D N V + ++ I C T Y + V Sbjct: 115 ------------GYSVNGGYGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKV 161 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY 247 PG + G+GG+G A+ +A G R+ AVDI+ K A+ LGA +N +D Sbjct: 162 TDTRPGQWVVISGIGGLGHVAVQYARAMG-LRVAAVDIDDAKLNLARRLGAEVAVNARDT 220 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 P + KE+ GG V + + GT + G+PP + + Sbjct: 221 -DPAAWLQKEI--GGAHGVL-VTAVSPKAFSQAIGMVRRGGTIALNGLPPGDFGTPIFDV 276 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 +L G T +G+I+G + A + A ++ + +N+ F L GK Sbjct: 277 -VLKGITIRGSIVGTRSDLQESLDF-----AAHGDVKATVS-TAKLDDVNDVFGRLREGK 329 Query: 368 -SIRTILMF 375 R +L F Sbjct: 330 VEGRVVLDF 338 >2DFV-A nrPDB Length = 347 Score = 280 bits (716), Expect = 7e-76, Method: Composition-based stats. Identities = 101/374 (27%), Positives = 157/374 (41%), Gaps = 37/374 (9%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM----VTPLPV 64 K A + + + EV+V P EV IK++A ICGTD H+ P Sbjct: 3 KMVAIMKTKPGYGAELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQ 62 Query: 65 ILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTL 124 I+GHE AG V +G GV ++ GD V CGKC C+ + + C + G Sbjct: 63 IMGHEVAGEVVEIGPGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIF---GVD 119 Query: 125 QDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSA 184 DG F++Y VV + K + P E L G+A Sbjct: 120 TDG------------------VFAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNA 156 Query: 185 VNVAKVTP--GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 V+ P G + + G G +GL I KA+GA +I + + + AK++GA I Sbjct: 157 VDTVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVI 216 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 NP + + ++EV+ GVD E G + L A G ++G+ P + Sbjct: 217 NPFE-EDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGKVTI 274 Query: 303 SMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFD 361 N +++ T G + G E + + K +LD +ITH F+K E F+ Sbjct: 275 DFNNLIIFKALTIYG--ITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFE 332 Query: 362 LLHSGKSIRTILMF 375 L+ +GK+ + + M Sbjct: 333 LMRAGKTGKVVFML 346 >2EER-A nrPDB Length = 347 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 99/376 (26%), Positives = 155/376 (41%), Gaps = 43/376 (11%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT---------P 61 +A L E+ KP +E++ + PK +V IK+ A G+C +D H+ G Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C D Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC---DSPRWL 118 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTG 180 G DG +++Y +V + K+ S +E + C T Sbjct: 119 GINYDG------------------AYAEYVLVPHYKYLYKLRRLSAVE-AAPLTCSGVTT 159 Query: 181 YGSAVNVAKVTPGSTCAVFGLGG-VGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 Y AV A + P T V G GG +G AI KA A II VD+ ++ AK GA Sbjct: 160 YR-AVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGAD 218 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 IN + P+ E+ + G D ++ T+ + G V+VG+ Sbjct: 219 YVINAS-SQDPVSEIRRITQGKGADAVIDLNNSEKTLSIYPYVLAKQ-GKYVMVGLFGAD 276 Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359 P++ L + G+++G + L A+ + ++T + E+ NE Sbjct: 277 LKYHA-PLITLNEVQFIGSLVGNQSDFLGIMSL-----AEAGKVKPMVTKTMKLEEANEA 330 Query: 360 FDLLHSGKSI-RTILM 374 D L + K++ R +L+ Sbjct: 331 IDNLENFKAVGRQVLV 346 >3GFB-A nrPDB Length = 350 Score = 270 bits (691), Expect = 6e-73, Method: Composition-based stats. Identities = 91/360 (25%), Positives = 146/360 (40%), Gaps = 39/360 (10%) Query: 23 SIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM----VTPLPVILGHEAAGIVESVG 78 + EV+V P EV IK++A ICGTD H+ P I+GHE AG V VG Sbjct: 18 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVG 77 Query: 79 EGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPI 138 GV ++ GD + CGKC CK+ + C + G DG Sbjct: 78 PGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIF---GVDMDG----------- 123 Query: 139 HHFLGISTFSQYTVVDENAVAKIDAASPLEKVC---LIGCGFSTGYGSAVNVAKVTPGST 195 F+ Y +V K P E +G T + G + Sbjct: 124 -------VFAHYAIVPAKNAWKNPKDMPPEYAALQEPLGNAVDTVLAGPI------AGRS 170 Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 + G G +GL I KA+GA +I + ++ + AK++GA +NP + + P++ V+ Sbjct: 171 TLITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFE-EDPVKFVM 229 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTW 315 GV+ E G + L G ++G+ P + N +++ Sbjct: 230 DITDGAGVEVFLEFSGAPKALEQGLKAVTP-GGRVSLLGLFPREVTIDFNNLIIFKALEV 288 Query: 316 KGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHSGKSIRTILM 374 G + G E + + + K +LD +ITH F+K E F+L+ +GK+ + + Sbjct: 289 HG--ITGRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTGKVVFF 346 >1PL8-A nrPDB Length = 356 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 89/366 (24%), Positives = 150/366 (40%), Gaps = 33/366 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGH 68 +++ +E + P +EV ++M +VGICG+D H G + P++LGH Sbjct: 10 SLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGH 69 Query: 69 EAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGT 128 EA+G VE VG V +KPGD+V CK N Sbjct: 70 EASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNL---------------SP 114 Query: 129 SRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 S F C P ++ + K+ E+ LI S G A Sbjct: 115 SIFFCATPPDD-----GNLCRFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGIH-ACRRG 167 Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-PQDY 247 VT G V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + ++ Sbjct: 168 GVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKES 227 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 + I ++ + + E G ++ A + + GT V+VG+ + + Sbjct: 228 PQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT-RSGGTLVLVGLGSEMTTVP---- 282 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 LL + I G F+ P ++ +K ++ L+TH P EK E F+ G Sbjct: 283 -LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGL 341 Query: 368 SIRTIL 373 ++ +L Sbjct: 342 GLKIML 347 >6N7L-A nrPDB Length = 353 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 99/369 (26%), Positives = 152/369 (41%), Gaps = 39/369 (10%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT--PLPVIL 66 KAAV+ +P I+EV V P +EV +K++A G+C TD H V G +P+I Sbjct: 13 TMKAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIP 72 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 GHE GIV + G VK GD V +P CG C C C Sbjct: 73 GHEGVGIVVACGPDA-MVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNG------- 124 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + F++Y + D V + + ++ I C T Y + Sbjct: 125 --------------GYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-KGL 169 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + PG A+ G+GG+G A+ KA G + A+D+ DK AK+LGA +N + Sbjct: 170 KETETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKLELAKKLGADLTVNAK 228 Query: 246 DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN 305 P + KE+ GG+ + + + GT + G+PP S L + Sbjct: 229 -TTDPGTYLHKEV--GGMHGAL-ITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELPIF 284 Query: 306 PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 +L T +G+I+G K + A + + A +T E IN+ FD + Sbjct: 285 ET-VLKRITVRGSIVGTRKDLQEALDF-----ANEGLVKATVTSA-KLEDINDVFDKMKK 337 Query: 366 GK-SIRTIL 373 G+ R +L Sbjct: 338 GQIDGRIVL 346 >3QE3-A nrPDB Length = 355 Score = 264 bits (674), Expect = 5e-71, Method: Composition-based stats. Identities = 91/366 (24%), Positives = 155/366 (42%), Gaps = 33/366 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGH 68 +++ +E + P +EV +KM +VGICG+D H G V P++LGH Sbjct: 9 SLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGH 68 Query: 69 EAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGT 128 EA+G V VG V ++PGD+V CK N Sbjct: 69 EASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNL---------------SP 113 Query: 129 SRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 + F C P ++ + N K+ E+ LI S G A A Sbjct: 114 TIFFCATPPDD-----GNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGIH-ACRRA 166 Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN-PQDY 247 VT G+ V G G +GL ++ KA GAA+++ D++ + +KAKE+GA + + Sbjct: 167 GVTLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNES 226 Query: 248 KKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 + I + ++ + + + E G ++ A + H GT V+VG+ + ++ Sbjct: 227 PEEIAKKVEGLLGSKPEVTIECTGVETSIQAGIYATHS-GGTLVLVGLGSEMTSVP---- 281 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 L+ T + I G F+ P ++ +K ++ L+TH P EK E F+ G Sbjct: 282 -LVHAATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGL 340 Query: 368 SIRTIL 373 ++ ++ Sbjct: 341 GLKVMI 346 >2DQ4-A nrPDB Length = 343 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 94/367 (25%), Positives = 157/367 (42%), Gaps = 33/367 (8%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT----MVTPLPVIL 66 +A ++ ++ + V P E+ +++ A ICGTD H+ P++ Sbjct: 2 RALAKLAPEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVT 61 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 GHE +G+VE+VG GV + GD V + C C C+ + CL + G +D Sbjct: 62 GHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQI---LGVDRD 118 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 G F++Y VV P E V I F + Sbjct: 119 G------------------GFAEYVVVPAENAWVNPKDLPFE-VAAILEPFGNAVHTVYA 159 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 + V+ G + + G G +GL A M +A+GA I+ D N + A A+ A +NP Sbjct: 160 GSGVS-GKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNP-- 215 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 ++ + EV++ +T GV+ E G + L+ G + I+G+P D + Sbjct: 216 LEEDLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIP-GGEARILGIPSDPIRFDLAG 274 Query: 307 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 L++ G T G + G + + + A + + L L+TH LP + E F LL SG Sbjct: 275 ELVMRGITAFG--IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASG 332 Query: 367 KSIRTIL 373 ++++ IL Sbjct: 333 QAVKVIL 339 >4CPD-A nrPDB Length = 347 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 95/364 (26%), Positives = 159/364 (43%), Gaps = 24/364 (6%) Query: 13 AVLWELKKPFSIEEVEVAPPK-AHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAA 71 AV++E K+ +++EV + + +++ GICG+D H+ G + +LGHE Sbjct: 3 AVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVLGHEFV 62 Query: 72 GIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRF 131 G VE+VGEG+ ++PGD V+ CG C C+ + N C + V G Sbjct: 63 GQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVY--------GYGPM 114 Query: 132 TCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 191 + + FS + K+ E+ G ST YG + ++ Sbjct: 115 FGNLQGAQAEILRVPFSNV------NLRKLPPNLSPERAIFAGDILSTAYGGLIQ-GQLR 167 Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 PG + AV G G VGL AI + GA++I+A+D ++ +A LGA IN + + P+ Sbjct: 168 PGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INAEQ-ENPV 225 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLT 311 + V E D G D E +G T+ +L G VGV N P L + Sbjct: 226 RRVRSETNDEGPDLVLEAVGGAATLSLALEMV-RPGGRVSAVGV----DNAPSFPFPLAS 280 Query: 312 GRTWKGAILGGFKSKECVPKLVADFMA-KKFSLDALITHVLPFEKINEGFDLLHSGKSIR 370 G G + V +A + + +++H LP E+ G++L ++++ Sbjct: 281 GLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDRKEALK 340 Query: 371 TILM 374 +L+ Sbjct: 341 VLLV 344 >5KIA-A nrPDB Length = 351 Score = 251 bits (642), Expect = 3e-67, Method: Composition-based stats. Identities = 87/368 (23%), Positives = 147/368 (39%), Gaps = 36/368 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT----MVTPLPVIL 66 KA E ++ V+ ++V IK+ ICGTD H+ P+P+ + Sbjct: 10 KALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHV 69 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 GHE G + +G+ V GD+V CG CR C+ + C Sbjct: 70 GHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLC-------------- 115 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 R F++Y + KI + + I F +A++ Sbjct: 116 -------RNTVGVGVNREGAFAEYLAIPAFNAFKIPPEIS-DDLAAIFDPFGNATHTALS 167 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 V G + G G +G+ A+ K GA ++ DIN + A+ +GAT +N Sbjct: 168 FNLV--GEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVS- 224 Query: 247 YKKPIQEVLKEM-TDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN 305 ++ +++V+ ++ G D E+ G + + SLL G ++G+PP + N Sbjct: 225 -RESLRDVMADLHMTEGFDVGLEMSG-VPSAFTSLLESMNHGGKVALLGIPPAQTAIDWN 282 Query: 306 PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 ++ G KG G + E K+VA + L +ITH + +GF + S Sbjct: 283 QVIF-KGLEIKGIY--GREMFETWYKMVAMLQSG-LDLSPIITHRFAVDDYEKGFAAMLS 338 Query: 366 GKSIRTIL 373 G+S + IL Sbjct: 339 GESGKVIL 346 >1R37-A nrPDB Length = 347 Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats. Identities = 101/376 (26%), Positives = 158/376 (42%), Gaps = 43/376 (11%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT---------P 61 +A L E+ KP S++E+ V PK +V IK+ A G+C +D H+ G Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LPV LGHE AG +E VG+ V GD V G C C+ E + C D Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC---DSPRWL 118 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDE-NAVAKIDAASPLEKVCLIGCGFSTG 180 G DG +++Y +V + K+ + +E + C T Sbjct: 119 GINFDG------------------AYAEYVIVPHYKYMYKLRRLNAVE-AAPLTCSGITT 159 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGL-SAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 Y AV A + P T V G GG A+ KA A II VD+ ++ AK GA Sbjct: 160 YR-AVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGAD 218 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 IN + P+ E+ + GVD ++ T+ + G V+VG+ Sbjct: 219 YVINAS-MQDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQ-GKYVMVGLFGAD 276 Query: 300 QNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEG 359 + P++ L+ + G+++G + +L A+ + +IT + E+ NE Sbjct: 277 LHYHA-PLITLSEIQFVGSLVGNQSDFLGIMRL-----AEAGKVKPMITKTMKLEEANEA 330 Query: 360 FDLLHSGKSI-RTILM 374 D L + K+I R +L+ Sbjct: 331 IDNLENFKAIGRQVLI 346 >4EEZ-A nrPDB Length = 348 Score = 248 bits (632), Expect = 4e-66, Method: Composition-based stats. Identities = 96/368 (26%), Positives = 150/368 (40%), Gaps = 34/368 (9%) Query: 11 KAAVLWELKKPF-SIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHE 69 KAAV+ + + E E+ K +E + M G+C TD HV +G +LGHE Sbjct: 2 KAAVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHE 61 Query: 70 AAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGT 128 GIV+ +G V++++ GD+V + CG C C + +C Sbjct: 62 GIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFC---------------- 105 Query: 129 SRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 R + ++ +V + K+ + I C T Y A+ V+ Sbjct: 106 -----REVKNAGYSVDGGMAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTY-KAIKVS 159 Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 V PG +FG GG+G AI K A++IAVDIN+DK AK++GA IN D Sbjct: 160 GVKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDV- 218 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPML 308 P+ E+ K GV + + + G V V VP LS+ P + Sbjct: 219 NPVDEIKKITGGLGVQSAIVC-AVARIAFEQAVASLKPMGKMVAVAVPNTEMTLSV-PTV 276 Query: 309 LLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK- 367 + G G+++G + A+ K I E+IN+ D + +GK Sbjct: 277 VFDGVEVAGSLVGTRLDLAEAFQFGAEGKVKP------IVATRKLEEINDIIDEMKAGKI 330 Query: 368 SIRTILMF 375 R ++ F Sbjct: 331 EGRMVIDF 338 >5YLN-A nrPDB Length = 356 Score = 245 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 98/368 (26%), Positives = 157/368 (42%), Gaps = 34/368 (9%) Query: 15 LWELKKPFSIEEVEVAPP---KAHEVRIKMVAVGICGTDDHVVSGTMVT-PLPVILGHEA 70 + KP V+V P K + +++V ICGTD H++ G + T ILGHE Sbjct: 7 AYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEG 66 Query: 71 AGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSR 130 GIVE VGEGV+ K GDKV+ + CGKC CK +C +++ G L DG Sbjct: 67 IGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHC-EDEGGWIFGHLIDGMQ- 124 Query: 131 FTCRRKPIHHFLGISTFSQYTVVD--ENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 ++Y V +N + E + ++ TGY V Sbjct: 125 -----------------AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKG 167 Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 KV PG + A+ G G VGL+A++ + A++I VD++ ++ A GAT +N D + Sbjct: 168 KVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPE 227 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPML 308 K I+E+ GVD + E +G T GT GV ++ + Sbjct: 228 KAIKEIYDLTDGRGVDVAIEAVGIPATFDFC-QKIIGVDGTVANCGVHGKPVEFDLDKLW 286 Query: 309 LLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK- 367 + + G S P+L+ + K + L+TH +I + +++ Sbjct: 287 IRN-----INVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSKAAD 341 Query: 368 --SIRTIL 373 +I+ I+ Sbjct: 342 HHAIKVII 349 >1H2B-A nrPDB Length = 359 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 91/378 (24%), Positives = 164/378 (43%), Gaps = 42/378 (11%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAP-PKAHEVRIKMVAVGICGTDDHVVSGTM----VTP 61 V + KAA L E KP IE+V+ +V +++ G+C TD H+V G Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 62 LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQ 121 LP LGHE G +E V EGV ++ GD VI G C C+ E +C + Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEF---P 129 Query: 122 GTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKV---CLIGCGFS 178 G DG F+++ +V K+ EK+ + Sbjct: 130 GLNIDG------------------GFAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGI 171 Query: 179 TGYGSAVNVAK-VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 T Y + A+ + PG+ A+ G+GG+G A+ K A +IA+D+ ++K A+ LG Sbjct: 172 TAYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERLG 231 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 A ++ + + P+++V++ GV+ + + +G T+ + G +IVG Sbjct: 232 ADHVVDAR--RDPVKQVMELTRGRGVNVAMDFVGSQATVDYTPYLLGR-MGRLIIVGY-G 287 Query: 298 DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKIN 357 ++ + +++G+++G + LV + K ++ I ++IN Sbjct: 288 GELRFPTIRVI-SSEVSFEGSLVGNYVELHE---LVTLALQGKVRVEVDI---HKLDEIN 340 Query: 358 EGFDLLHSGKSI-RTILM 374 + + L G+ + R +L+ Sbjct: 341 DVLERLEKGEVLGRAVLI 358 >5VM2-A nrPDB Length = 347 Score = 243 bits (621), Expect = 7e-65, Method: Composition-based stats. Identities = 94/358 (26%), Positives = 146/358 (40%), Gaps = 34/358 (9%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDH-VVSGTMVTPLP----VILGHE 69 + ++ I E+ PK EV IK+ VGICG+D H SG + P + LGHE Sbjct: 7 ILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHE 66 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTS 129 AG V +VG V KPGD+V CG CR C + N C D Q + + Sbjct: 67 CAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALT 126 Query: 130 RFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 + C E+ K+ + L+ + G +A+ +A Sbjct: 127 HYLCH-------------------PESFTYKLPDNMDTMEGTLVE-PAAVGMHAAM-LAD 165 Query: 190 VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 V PG + G G +GL + CK GA I VD+ + + A A++LGAT IN + Sbjct: 166 VKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAK-ED 224 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL 309 I + D G D FE G T+ + G +IVG P + ++ L Sbjct: 225 TIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMR-GGKIMIVGTVPGASAINF----L 279 Query: 310 LTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 R I F+ P + + +F + +++TH+ + + + F+ + K Sbjct: 280 KINREV--TIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNK 335 >5ENV-A nrPDB Length = 347 Score = 241 bits (615), Expect = 4e-64, Method: Composition-based stats. Identities = 92/363 (25%), Positives = 146/363 (40%), Gaps = 35/363 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGH 68 K + +E +++ V PKA+E+ I + G+C TD H G P LP++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E AG+V +GE V K GD I C C C+ + C D+S Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLS--------- 117 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 + +F QY D A I + L +V I C T Y A+ Sbjct: 118 ------------GYTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKS 164 Query: 188 AKVTPGSTCAVFG-LGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ G GG+G A+ KA G R++ +D + K + +G I+ Sbjct: 165 ANLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTK 223 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 K + VLK TDGG V + AS A GT+V+VG+P ++ S Sbjct: 224 EKDIVGAVLKA-TDGGAHGVINVSVSEAAIEASTRYV-RANGTTVLVGMPAGAKCCSDVF 281 Query: 307 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 ++ + G+ +G + DF A+ + V+ + E ++ + G Sbjct: 282 NQVVKSISIVGSYVGNRADT----REALDFFARGLVKSPI--KVVGLSTLPEIYEKMEKG 335 Query: 367 KSI 369 + + Sbjct: 336 QIV 338 >1YKF-A nrPDB Length = 352 Score = 240 bits (612), Expect = 8e-64, Method: Composition-based stats. Identities = 98/349 (28%), Positives = 154/349 (44%), Gaps = 30/349 (8%) Query: 24 IEEVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVT 82 E E P + ++ +AV C +D H V G + +ILGHEA G V VG V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 83 TVKPGDKVI-PLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHF 141 KPGD+V+ P P + + + G + G +F+ + + Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW-KFSNVKDGV--- 119 Query: 142 LGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL 201 F D N +A + PLE +I +TG+ A +A + G+T AV G+ Sbjct: 120 --FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAVLGI 175 Query: 202 GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 G VGL A+ G K GA RIIAV AK GAT+ +N +D PI+ + +T+G Sbjct: 176 GPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMNLTEG 233 Query: 262 -GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL---LTGRTWKG 317 GVD + G D +MA+ + + GT V + + L + + + +T KG Sbjct: 234 KGVDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKG 292 Query: 318 AILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHS 365 + G + + + +L+ K+ L+THV F+ I + F L+ Sbjct: 293 GLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >1UUF-A nrPDB Length = 369 Score = 236 bits (603), Expect = 9e-63, Method: Composition-based stats. Identities = 86/362 (23%), Positives = 144/362 (39%), Gaps = 31/362 (8%) Query: 8 IKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTPLPVIL 66 +K KA + K+P ++ P ++V+I++ G+C +D H V T P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 GHE G V +VG+ V PGD V + + C C C++ NYC Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYC------------- 127 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKI-DAASPLEKVCLIGCGFSTGYGSA 184 D + P + +SQ VV E V +I L V + C T Y Sbjct: 128 DHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPL 187 Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 + + PG V G+GG+G I A GA ++A ++ K AK LGA E +N Sbjct: 188 RHW-QAGPGKKVGVVGIGGLGHMGIKLAHAMGA-HVVAFTTSEAKREAAKALGADEVVNS 245 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSM 304 ++ + + DF + + + GT +VG P Sbjct: 246 RNADEMAAHL------KSFDFILNTVAAPHNL-DDFTTLLKRDGTMTLVGAPATPHKSPE 298 Query: 305 NPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLH 364 L++ R G+++GG + + DF A+ + + ++ ++INE ++ + Sbjct: 299 VFNLIMKRRAIAGSMIGGIPETQE----MLDFCAEHGIVADI--EMIRADQINEAYERML 352 Query: 365 SG 366 G Sbjct: 353 RG 354 >4EJ6-A nrPDB Length = 370 Score = 236 bits (603), Expect = 9e-63, Method: Composition-based stats. Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 30/364 (8%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAG 72 AV E S+ V + P ++ +K+ A GICGTD H++ G + PV LGHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 73 IVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 IV G V + PG ++ CG+C C+ N C G +DG Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAI---GIHRDG----- 137 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 F++Y +V +I L+ V C V+++ + Sbjct: 138 -------------GFAEYVLVPRKQAFEIP--LTLDPVHGAFCEPLACCLHGVDLSGIKA 182 Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ--DYKKP 250 GST A+ G G +GL + + AGA +I K A+E+GAT ++P D + Sbjct: 183 GSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEA 242 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 310 I + + GGVD E G +T+ S +A GT VI+GV P + + + P +L Sbjct: 243 IAGPVG-LVPGGVDVVIECAGVAETVKQSTR-LAKAGGTVVILGVLPQGEKVEIEPFDIL 300 Query: 311 TGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIR 370 +LG F + + +D +I+ + ++ + + ++ Sbjct: 301 FRELR---VLGSFINPFVHRRAADLVATGAIEIDRMISRRISLDEAPDVISNPAAAGEVK 357 Query: 371 TILM 374 +++ Sbjct: 358 VLVI 361 >5H82-A nrPDB Length = 389 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 80/337 (23%), Positives = 132/337 (39%), Gaps = 17/337 (5%) Query: 33 KAHEVRIKMVAVGICGTDDHVVSGTMVT-PLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 H+V+ K++ G+C D T T P + GHE GIV +G V K GDKV Sbjct: 52 GEHDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVG 111 Query: 91 IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQY 150 + I CGKC C YC K + D + +S Sbjct: 112 VGNFIGSCGKCERCNEGLEPYCPKV-IYTDGTAFSDENNTVYGDVSGDGEDRIYGGYSNI 170 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIM 210 V +E V + PL I CG Y + PG + V G G +G A+ Sbjct: 171 MVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKLAVK 230 Query: 211 GCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI 270 KA GA + K ++ G + ++ ++ + + +D F+ + Sbjct: 231 FAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKEPEE------MKAAESTLDGIFDCV 284 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVP 330 + + LL + GT V++GV ++ L ++P LL+ R + G+I G K + Sbjct: 285 PSVHP-LHPLLNLLKFEGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMKETQE-- 340 Query: 331 KLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 + DF AK + + ++P + +N + + G Sbjct: 341 --MLDFAAKHNIVSDI--ELIPMDYVNTALERIAKGN 373 >3FSR-A nrPDB Length = 352 Score = 234 bits (598), Expect = 4e-62, Method: Composition-based stats. Identities = 89/348 (25%), Positives = 143/348 (41%), Gaps = 28/348 (8%) Query: 24 IEEVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVT 82 E E P + ++ +AV C +D H V G + +ILGHEA G V VG V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 83 TVKPGDKVI-PLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHF 141 KPGD+V+ P P + + + G + G +F+ + + Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW-KFSNVKDGV--- 119 Query: 142 LGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL 201 F D N +A + PLE +I +TG+ A +A + GS+ V G+ Sbjct: 120 --FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVVIGI 175 Query: 202 GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 G VGL I G K GA RII V AK GAT+ +N ++ + +V+K Sbjct: 176 GAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKLTNGK 234 Query: 262 GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL---LTGRTWKGA 318 GVD G +T+ ++ + G + L + + + +T KG Sbjct: 235 GVDRVIMAGGGSETLSQAVSMV-KPGGIISNINYHGSGDALLIPRVEWGCGMAHKTIKGG 293 Query: 319 ILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHS 365 + G + + + +L+ K+ L+THV F+ I + F L+ Sbjct: 294 LCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >1E3J-A nrPDB Length = 352 Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats. Identities = 82/371 (22%), Positives = 150/371 (40%), Gaps = 39/371 (10%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILG 67 +AVL++ +E+ + PK EV ++M VGICG+D H + P+++G Sbjct: 7 SAVLYKQND-LRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 HEA+G V VG+ V +K GD+V C +C+ CK + N C Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLT----------- 114 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 C P ++Y V + K+ LE+ L+ S G A Sbjct: 115 ----FCATPPDD-----GNLARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGVH-ACRR 163 Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE--CINP- 244 A V G+T V G G +GL +++ KA GA ++ + + AK GA ++P Sbjct: 164 AGVQLGTTVLVIGAGPIGLVSVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVVDPA 222 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSM 304 ++ + I E ++ + + + G + + GT ++VG+ + Sbjct: 223 KEEESSIIERIRSAIGDLPNVTIDCSGNEKCITIGI-NITRTGGTLMLVGMGSQMVTVP- 280 Query: 305 NPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD--L 362 L+ + I F+ P + + + ++ L+TH E+ + F+ Sbjct: 281 ----LVNACAREIDIKSVFRYCNDYPIALEMVASGRCNVKQLVTHSFKLEQTVDAFEAAR 336 Query: 363 LHSGKSIRTIL 373 + +I+ ++ Sbjct: 337 KKADNTIKVMI 347 >3FPC-A nrPDB Length = 352 Score = 231 bits (588), Expect = 5e-61, Method: Composition-based stats. Identities = 87/348 (25%), Positives = 141/348 (40%), Gaps = 28/348 (8%) Query: 24 IEEVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEGVT 82 E E P + ++ +AV C +D H V G + +ILGHEA G V VG V Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVK 73 Query: 83 TVKPGDKVI-PLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHF 141 KPGD+V+ P P + + + G + G +F+ + + Sbjct: 74 DFKPGDRVVVPAITPDWRTSEVQRGYHQH----------SGGMLAGW-KFSNVKDGV--- 119 Query: 142 LGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL 201 F D N +A + PLE +I +TG+ A +A + G T V G+ Sbjct: 120 --FGEFFHVNDADMN-LAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDTVCVIGI 175 Query: 202 GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 G VGL ++ G GA RI AV K A E GAT+ IN ++ ++++LK Sbjct: 176 GPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN-GDIVEQILKATDGK 234 Query: 262 GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL---LTGRTWKGA 318 GVD G + T ++ + V + N+ + + + G Sbjct: 235 GVDKVVIAGGDVHTFAQAVKMI-KPGSDIGNVNYLGEGDNIDIPRSEWGVGMGHKHIHGG 293 Query: 319 ILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHS 365 + G + + + +L+ K+ L+THV F+ I + F L+ Sbjct: 294 LCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >3FPL-A nrPDB Length = 351 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 97/353 (27%), Positives = 154/353 (43%), Gaps = 34/353 (9%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEG 80 E E +++ ++ +AV C +D H V G + +ILGHEA G V VG Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 81 VTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIH 139 V KPGD+V +P P + Q Q ++ K + Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEV-----------------QAGFQQHSNGMLAGWKFSN 114 Query: 140 HFLGISTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 G+ F +Y V++ +A + PLE +I +TG+ A +A + G+T A Sbjct: 115 FKDGV--FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVA 171 Query: 198 VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 257 V G+G VGL A+ G K GA RIIAV AK GAT+ +N +D PI+ + Sbjct: 172 VLGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKD--GPIESQIMN 229 Query: 258 MTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL---LTGR 313 +T+G GVD + G D +MA+ + + GT V + + L + + + + Sbjct: 230 LTEGKGVDAAIIAGGNAD-IMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHK 288 Query: 314 TWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHS 365 T KG + G + + + + + + L L+THV F+ I E L+ Sbjct: 289 TIKGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKD 339 >5YAT-A nrPDB Length = 350 Score = 227 bits (579), Expect = 6e-60, Method: Composition-based stats. Identities = 91/363 (25%), Positives = 143/363 (39%), Gaps = 35/363 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV--TPLPVILGH 68 KA + P +++ V PK++E+ I + G+C TD H G LP++ GH Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGGH 69 Query: 69 EAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 E AG+V + GE VT + GD I C C C + C K D+S Sbjct: 70 EGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLS--------- 120 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 F +F QY D A+I + L +V I C T Y A+ Sbjct: 121 ------------GFTHDGSFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALKT 167 Query: 188 AKVTPGSTCAV-FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 A + G A+ GG+G A+ KA G R++ +D DK K LGA ++ Sbjct: 168 ADLRIGQWVAISGAGGGLGSLAVQYAKALG-LRVLGIDGGADKGEFVKSLGAEVFVDFTK 226 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 K + EV K +T+GG V + S+ G V+VG+P + S Sbjct: 227 TKDVVAEVQK-LTNGGPHGVINVSVSPHAINQSVQYV-RTLGKVVLVGLPSGAVVNSDVF 284 Query: 307 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 +L KG+ +G + L + K ++ ++ + ++ + +G Sbjct: 285 WHVLKSIEIKGSYVGNREDSAEAIDLFTRGLVKAPI------KIIGLSELAKVYEQMEAG 338 Query: 367 KSI 369 I Sbjct: 339 AII 341 >1KEV-A nrPDB Length = 351 Score = 224 bits (570), Expect = 6e-59, Method: Composition-based stats. Identities = 88/352 (25%), Positives = 143/352 (40%), Gaps = 32/352 (9%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVV-SGTMVTPLPVILGHEAAGIVESVGEG 80 E E +++ ++ +AV C +D H V G + +ILGHEA G V VG Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 81 VTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIH 139 V KPGD+V +P P + Q Q ++ K + Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEV-----------------QAGFQQHSNGMLAGWKFSN 114 Query: 140 HFLGISTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCA 197 G+ F +Y V++ +A + PLE +I +TG+ A +A + GS+ Sbjct: 115 FKDGV--FGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVV 171 Query: 198 VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKE 257 V G+G VGL I G K GA RII V AK GAT+ +N ++ + +V+K Sbjct: 172 VIGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKN-GHIVDQVMKL 230 Query: 258 MTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL---LTGRT 314 GVD G +T+ ++ + G + L + + + +T Sbjct: 231 TNGKGVDRVIMAGGGSETLSQAVSMV-KPGGIISNINYHGSGDALLIPRVEWGCGMAHKT 289 Query: 315 WKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLP-FEKINEGFDLLHS 365 KG + G + + + + + + L L+THV F+ I E L+ Sbjct: 290 IKGGLCPGGRLRAEMLR--DMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKD 339 >4OAQ-A nrPDB Length = 367 Score = 223 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 86/367 (23%), Positives = 150/367 (40%), Gaps = 34/367 (9%) Query: 16 WELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM--VTPLPVILGHEAAGI 73 W K S E ++ P H+V +K G+C +D H +S + +++GHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGE 76 Query: 74 VESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 V +VG+ VT K GD+V I A C C+ C + YC + G + + Sbjct: 77 VIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYC------------KQGAATYN 124 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV-NVAKVT 191 + ++++ +S +++ DE V I P + C T + + N+ Sbjct: 125 SKDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLDA 184 Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G + G+GG+G A+ A GA + A + K +A +LGA + + + K Sbjct: 185 RGKNVGIIGIGGLGHLALQFANAMGA-NVTAFSRSSSKKEQAMKLGAHDFVATGEDKTWY 243 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMAS-LLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 310 + D DF +D + S L + V VG+PP ++P L Sbjct: 244 KNY-----DDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPFTFL 298 Query: 311 -TGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHV-LPFEKINEGFDLLHSGKS 368 G ++ ++LG + + L A K ++ +I V + E + D H+G Sbjct: 299 QQGASFGSSLLGSKTEVKEMLNL-----AAKHNVRPMIEEVPISEENCAKALDRCHAG-D 352 Query: 369 IRTILMF 375 +R +F Sbjct: 353 VRYRFVF 359 >4GKV-A nrPDB Length = 336 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 98/367 (26%), Positives = 153/367 (41%), Gaps = 36/367 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEA 70 KAAV+ + + + K E +KM G+C TD HV +G VILGHE Sbjct: 2 KAAVVTKDHH-VDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEG 60 Query: 71 AGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTS 129 G+V VG GVT++KPGD+ + CG C C + C Sbjct: 61 IGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLC----------------- 103 Query: 130 RFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 R + ++ +V + K+ I C T Y AV ++K Sbjct: 104 ----RSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTY-KAVKLSK 158 Query: 190 VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 + PG A++GLGG+G A+ K A++IA+D+N ++ A E+GA IN + + Sbjct: 159 IRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINS--HTE 216 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL 309 ++++E T G V S + A G V VG+PP+S +L + P L+ Sbjct: 217 DAAKIVQEKTGGAHAAV--VTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDI-PRLV 273 Query: 310 LTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKS- 368 L G G+++G + + A+ K + P IN F + GK Sbjct: 274 LDGIEVVGSLVGTRQDLTEAFQFAAE---GKVVPK---VALRPLADINTIFTEMEEGKIR 327 Query: 369 IRTILMF 375 R ++ F Sbjct: 328 GRMVIDF 334 >5K1S-A nrPDB Length = 362 Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats. Identities = 93/370 (25%), Positives = 150/370 (40%), Gaps = 36/370 (9%) Query: 11 KAAVLWELK--KPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TPLPVILG 67 KA VL +E + + P EV +++ A G+C D G + T +P ILG Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 HEAAG V VG K GD+ L CG C +C++ ++ C + Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTD------------ 126 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNV 187 +RF P ++Q+ V + ++ A+ P + + C T + Sbjct: 127 -NRFFGEELP-------GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTR 178 Query: 188 AKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 KV G T + G GGVGLS++ + GA R+IAV ++ K KE GA E I + Sbjct: 179 GKVRAGETVLITGASGGVGLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVIVSRG 237 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 +V K GVD + E++G L G V+VG +S + +NP Sbjct: 238 L-DFASDVRKRTQGAGVDVAVEIVGSA--TFDQTLKSMAPGGRVVVVG-NLESGMVQLNP 293 Query: 307 MLLLTGR-TWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 L++ GA + +L A + +T +P + + L + Sbjct: 294 GLVIVKELEILGAYATTQAELDEALRLTAT-----GGVRQFVTDAVPLAEAAKAHFRLEN 348 Query: 366 GK-SIRTILM 374 + + R +L+ Sbjct: 349 REVAGRLVLV 358 >3TWO-A nrPDB Length = 348 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 91/366 (24%), Positives = 148/366 (40%), Gaps = 38/366 (10%) Query: 8 IKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP-LPVIL 66 ++ K ++ + F + +V I ++ GIC +D H P+I Sbjct: 3 VQSKGFAIFSKDEHFKPHDFSRHAVGPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIP 62 Query: 67 GHEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 GHE AGI++ VG+GV K GD V + + C C+ CK + +C K + Sbjct: 63 GHEIAGIIKEVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKVVFT------- 115 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 + C + + +S VVDEN V +D +PLEKV + C T Y + Sbjct: 116 -----YDCLDSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTYSP-L 169 Query: 186 NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NP 244 +KVT G+ V G GG+G A+ A GA + N+ K A +G +P Sbjct: 170 KFSKVTKGTKVGVAGFGGLGSMAVKYAVAMGA-EVSVFARNEHKKQDALSMGVKHFYTDP 228 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP--DSQNL 302 + K+ + DF I + L G +VG+PP + L Sbjct: 229 KQCKEEL------------DFIISTIPTHYDLKDYLKLLT-YNGDLALVGLPPVEVAPVL 275 Query: 303 SMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362 S+ + L R G+++GG K + + K ++ I +L + I+ + Sbjct: 276 SVFDFIHLGNRKVYGSLIGGIKETQEMVDFSI-----KHNIYPEIDLILG-KDIDTAYHN 329 Query: 363 LHSGKS 368 L GK+ Sbjct: 330 LTHGKA 335 >1YQX-A nrPDB Length = 366 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 78/363 (21%), Positives = 133/363 (36%), Gaps = 31/363 (8%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TPLPVILGHEAAGI 73 + S +VR K++ G+C +D H + + P++ GHE G Sbjct: 22 ARDQSGHLSPFNFSRRATGEEDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGE 81 Query: 74 VESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 V VG V V GDKV + + C C C N NYC K ++ DGT + Sbjct: 82 VTEVGSKVKKVNVGDKVGVGCLVGACHSCESCANDLENYCPKMILTYAS-IYHDGTITY- 139 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 +S + V +E + + PL+ + C T Y P Sbjct: 140 ------------GGYSNHMVANERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEP 187 Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + GLGG+G A+ KA G+ + K K GA + +D ++ Sbjct: 188 GKHIGIVGLGGLGHVAVKFAKAFGSKVTVISTSPSKKEEALKNFGADSFLVSRDQEQ--- 244 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTG 312 + G +D + + + ++ L ++ G ++VG P L L+ Sbjct: 245 ---MQAAAGTLDGIIDTVSAVHPLL-PLFGLLKSHGKLILVGAPEKPLELPAF-SLIAGR 299 Query: 313 RTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTI 372 + G+ +GG K + + DF AK + V+ + +N + L +R Sbjct: 300 KIVAGSGIGGMKETQE----MIDFAAKHNITADI--EVISTDYLNTAMERLAK-NDVRYR 352 Query: 373 LMF 375 + Sbjct: 353 FVI 355 >4OH1-A nrPDB Length = 351 Score = 218 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 82/365 (22%), Positives = 140/365 (38%), Gaps = 47/365 (12%) Query: 20 KPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-------TPLPVILGHEAAG 72 + E + PK E+RIK+V ICG+D H+++G + + LP+ GHE +G Sbjct: 19 GTVDMMEAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSG 78 Query: 73 IVESVGEGVT--TVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSR 130 +++ VG K G KV+ CG C C+ + N C Sbjct: 79 VIDKVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMGYR------------ 126 Query: 131 FTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKV 190 ++ FS+Y V + + I + L+ L+ T S+ AK+ Sbjct: 127 -------------MNGFSEYAVYHMSQIFPIPDDADLKDYALVE--PLTVALSSAEQAKI 171 Query: 191 TPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 + G + A+ G GG+G+ + + AGA+ I DI +K A E GA +N + + Sbjct: 172 SYGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EG 229 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN--PML 308 + E E+ G D E G L G +V + L +N L Sbjct: 230 VAERAIELAGGRYDCVLEGTGATAAAKLGLQLLAR-DGDAVYFAMYGKDPILPVNLQSDL 288 Query: 309 LLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKS 368 + G I G ++ + + M + +I + F+ L+S K Sbjct: 289 YWDQKHIHGMIQGAWQFPKSIR------MIPRMDFSKIIQKEHTLTNYKQAFEDLYSKKY 342 Query: 369 IRTIL 373 + ++ Sbjct: 343 AKIVI 347 >3M6I-A nrPDB Length = 363 Score = 217 bits (553), Expect = 6e-57, Method: Composition-based stats. Identities = 77/364 (21%), Positives = 145/364 (39%), Gaps = 39/364 (10%) Query: 15 LWELKKPFSIEEVEVAPP-KAHEVRIKMVAVGICGTDDHVVSGTMVTPLPV----ILGHE 69 LW + S+E V+ K EV + + + GICG+D H + P+ V +LGHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 70 AAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTS 129 +AG V +V V ++K GD+V C C C N C + D + + Sbjct: 80 SAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTP-PVPGLLR 138 Query: 130 RFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAK 189 R+ H +G ++ +++ +VA + + A Sbjct: 139 RYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQRAG 176 Query: 190 VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK 249 V G + G G +GL ++ KAAGA ++ DI++ + AKE+ E + + + Sbjct: 177 VRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEI-CPEVVTHKVERL 235 Query: 250 PIQEVLKEMTD--GGVD--FSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN 305 +E K++ + GG++ + E G ++ A+ + + G ++GV + + Sbjct: 236 SAEESAKKIVESFGGIEPAVALECTGVESSI-AAAIWAVKFGGKVFVIGVGKNEIQIP-- 292 Query: 306 PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 + + + ++ P+ + L L+TH P E + F+ Sbjct: 293 ---FMRASVREVDLQFQYRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFETASD 349 Query: 366 GKSI 369 K+ Sbjct: 350 PKTG 353 >5Z0C-A nrPDB Length = 374 Score = 217 bits (553), Expect = 6e-57, Method: Composition-based stats. Identities = 95/370 (25%), Positives = 136/370 (36%), Gaps = 34/370 (9%) Query: 1 MSTAGKVIKCKAAVLWELKKP---FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT 57 M + KA V W + P S +V K++ GIC +D H + Sbjct: 3 MGNGTEEHTVKA-VGWAARDPSGHLSPFTFSRRATGELDVTFKVLYCGICHSDLHYIKNE 61 Query: 58 MVTP-LPVILGHEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKN 115 P + GHE G V VG V K GDKV + + C C C N NYC N Sbjct: 62 WSNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGCIVGSCHSCPNCNNHLENYC-PN 120 Query: 116 DVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 + DGT L +S VV E+ +I A PL+ + C Sbjct: 121 RILTFGSRYYDGT-------------LNHGGYSDLMVVQEHFAVRIPDALPLDSAAPLLC 167 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 T Y PG V GLGG+G A+ KA G + K Sbjct: 168 AGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAKAFGVKVTVVSTSPAKKEDAISG 227 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 LGA I D ++ V G +D + + + L+ ++ G V+VG Sbjct: 228 LGAHSFILSTDAEQMQAAV------GTMDGIIDTV-SASHPLPPLISLLKSHGKLVMVGD 280 Query: 296 PPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEK 355 PP L + P LLL + G+ +GG K + + DF AK+ + V+P + Sbjct: 281 PPKPLELPVFP-LLLGRKMVAGSAIGGMKETQE----MIDFAAKEGVRADV--EVIPMDY 333 Query: 356 INEGFDLLHS 365 +N + Sbjct: 334 VNTAMQRVSK 343 >2H6E-A nrPDB Length = 344 Score = 214 bits (544), Expect = 6e-56, Method: Composition-based stats. Identities = 95/378 (25%), Positives = 158/378 (41%), Gaps = 45/378 (11%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSG---TMVTPLP 63 ++K KAA+L + +P SIE+V + P+ EV I++ G+C TD V G LP Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGT 123 +ILGHE AG + VGE + VK GD V+ A CR C+ + N C Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNIC----------- 108 Query: 124 LQDGTSRFTCRRKPIHHFLGISTFSQYTVV-DENAVAKIDAASPLEKVCLIGCGFSTGYG 182 + + I FS+Y +V + K+++ SP+E + +T G Sbjct: 109 ----------KNQIIPGQTTNGGFSEYMLVKSSRWLVKLNSLSPVE-AAPLADAGTTSMG 157 Query: 183 S---AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKA-AGAARIIAVDINKDKFAKAKELGA 238 + A+ V G+GG+ + I KA I+ + +K A ELGA Sbjct: 158 AIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFALELGA 217 Query: 239 TECINPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 +D + ++ ++TDG G + +++G +T L G ++VG+ Sbjct: 218 DYVSEMKD----AESLINKLTDGLGASIAIDLVGTEETTYN-LGKLLAQEGAIILVGMEG 272 Query: 298 DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKIN 357 +L + + G+ G E V +L ++ + I V P + IN Sbjct: 273 KRVSLEAFDTAV-WNKKLLGSNYGSLNDLEDVVRL-----SESGKIKPYIIKV-PLDDIN 325 Query: 358 EGFDLLHSGK-SIRTILM 374 + F L G+ R ++ Sbjct: 326 KAFTNLDEGRVDGRQVIT 343 >4ILK-A nrPDB Length = 359 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 87/367 (23%), Positives = 141/367 (38%), Gaps = 36/367 (9%) Query: 13 AVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSG-TMVTPLPVILGHEAA 71 ++L E SI E E+ P A EVR+K+ GICG+D H+ G P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 72 GIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRF 131 G++++VGEGV + + G++V + CG C C + N C V G DG Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAV---LGVHADG---- 135 Query: 132 TCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 191 FS+Y VV KI A + +I T + + T Sbjct: 136 --------------GFSEYAVVPAKNAWKIPEAVADQYAVMIE--PFTIAANVTGHGQPT 179 Query: 192 PGSTCAVFGLGGVGLSAIMGCK-AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 T V+G G +GL+ + K +I D ++ KAKE GA IN + + P Sbjct: 180 ENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--NSQTP 237 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 310 + E E + + ++ A V++G + + + Sbjct: 238 LGESFAEKGIK-PTLIIDAACHPSILKEAVTLASPAA-RIVLMGFSSEPSEVIQQG---I 292 Query: 311 TGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLL--HSGKS 368 TG+ +I + P ++ + LITH F+ + + L Sbjct: 293 TGKEL--SIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFELDQKHC 350 Query: 369 IRTILMF 375 + +L F Sbjct: 351 CKVLLTF 357 >4UEJ-A nrPDB Length = 346 Score = 208 bits (529), Expect = 4e-54, Method: Composition-based stats. Identities = 88/369 (23%), Positives = 146/369 (39%), Gaps = 33/369 (8%) Query: 13 AVLWELKKPFSIEEVEVAPPKA-HEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAA 71 +V+ + + E + K EVR+K+ + G+CG+D + P+ LGHE + Sbjct: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 Query: 72 GIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRF 131 G +++VG GV + PGD V + + C C C + C K D G+ +DG Sbjct: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFI---GSRRDG---- 115 Query: 132 TCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT 191 F++Y VV V + P+E I T A ++A+ Sbjct: 116 --------------GFAEYIVVKRKNVFALPTDMPIEDGAFIE--PITVGLHAFHLAQGC 159 Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP- 250 + G G +GL AI A GA + A+DI+ +K A AK GA + N + P Sbjct: 160 ENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQ 219 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM--L 308 +Q VL+E+ E G T+ ++ +VG +L+ + Sbjct: 220 MQSVLRELRFN--QLILETAGVPQTVELAVEIAGPHA-QLALVGTLHQDLHLTSATFGKI 276 Query: 309 LLTGRTWKGAILGGFKSK--ECVPKLVADFMAKKFSLDALITHVLPFEKINEGF-DLLHS 365 L T G+ + + +K SL+ LI H FE + D+ + Sbjct: 277 LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARN 336 Query: 366 GKSIRTILM 374 + +L+ Sbjct: 337 AMPGKVLLI 345 >3IP1-A nrPDB Length = 404 Score = 208 bits (529), Expect = 4e-54, Method: Composition-based stats. Identities = 86/384 (22%), Positives = 142/384 (36%), Gaps = 47/384 (12%) Query: 15 LWELKKPFSIEEVEVAPP-KAHEVRIKMVAVGICGTDDHVVSGT--------MVTPLPVI 65 +W + +EEV K E+ IK+ A GICG+D H+ +T PV Sbjct: 36 VWRYPE-VRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVT 94 Query: 66 LGHEAAGIVESVGEGV------TTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSN 119 LGHE +G+V G + G+ V + CG CR C N+C N Sbjct: 95 LGHEFSGVVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCEN---LN 151 Query: 120 PQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFS- 178 G DG F++Y VD + + + + S Sbjct: 152 ELGFNVDG------------------AFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSL 193 Query: 179 -----TGYGSA-VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAK 232 Y + V + PG + G G +GL+A+ K AGA+++I + ++ + Sbjct: 194 VEPTSVAYNAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNL 253 Query: 233 AKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL-LCCHEACGTSV 291 AKELGA I+P + ++ VL G E G + + A G + Sbjct: 254 AKELGADHVIDPTK-ENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINA 312 Query: 292 IVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVL 351 V + + + R + G P++++ MA + +I+ + Sbjct: 313 TVAIVARADAKIPLTGEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTV 371 Query: 352 PFEKINEGFDLLHSGKSIRTILMF 375 E+I E L + KS+ + M Sbjct: 372 SMEEIPEYIKRLQTDKSLVKVTML 395 >2OUI-A nrPDB Length = 360 Score = 206 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 81/350 (23%), Positives = 137/350 (39%), Gaps = 32/350 (9%) Query: 24 IEEVEVAPPKAHEVRIKMVAVGICGTDDH-VVSGTMVTPLPVILGHEAAGIVESVGEGVT 82 E ++ + ++ +A+ C +D H V +G + +ILGHEA G + VG V Sbjct: 14 WIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVK 73 Query: 83 TVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHF 141 +K GDKV +P P G+ + + G + G Sbjct: 74 RLKVGDKVIVPAITPDWGEEESQRGYPMH----------SGGMLGGWK---------FSN 114 Query: 142 LGISTFSQYTVVDEN--AVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF 199 FS+ V+E +A + E ++ +TG+ A +A + G T V Sbjct: 115 FKDGVFSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDTVCVI 173 Query: 200 GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 G+G VGL ++ G GA RI AV K A E GAT+ IN ++ ++++LK Sbjct: 174 GIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKN-GDIVEQILKATD 232 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL---LTGRTWK 316 GVD G + T ++ + V + N+ + + + Sbjct: 233 GKGVDKVVIAGGDVHTFAQAVKMI-KPGSDIGNVNYLGEGDNIPIPRSEWGVGMGHKHIH 291 Query: 317 GAILGGFKSKECVPKLVADFMAKKFSLDALITHVL-PFEKINEGFDLLHS 365 G + G + + + KL + K LITH EK+ + L+ + Sbjct: 292 GGLTPGGRVR--MEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKN 339 >6FG0-A nrPDB Length = 352 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 82/361 (22%), Positives = 136/361 (37%), Gaps = 32/361 (8%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS---GTMVTPLPVILG 67 KA E+ + ++ P E+ +K+ A G+C +D V+ LP+ LG Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 68 HEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127 HE G V +GEGVT GD V CG C C NYC Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYCT-------------- 107 Query: 128 TSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN- 186 R + + ++Y +VD + T Y + Sbjct: 108 --RAADLGITPPGYGSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAISRV 165 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 + + PGST V G+GG+G I +A AAR+IAVD++ D+ A A+E+GA + Sbjct: 166 LPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKS-- 223 Query: 247 YKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMN 305 + ++E+T G G F+ +G T+ + G +VG+ + + Sbjct: 224 -GAGAADAIRELTGGQGATAVFDFVGAQSTIDTA-QQVVAVDGHISVVGIHAGAHA-KVG 280 Query: 306 PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 ++ G + G + ++VA A + + T ++ + L Sbjct: 281 FWMIPFGASVVTPYWGTRS---ELMEVVALARAGRLDIH---TETFTLDEGPAAYRRLRE 334 Query: 366 G 366 G Sbjct: 335 G 335 >5FI5-A nrPDB Length = 357 Score = 204 bits (518), Expect = 6e-53, Method: Composition-based stats. Identities = 80/346 (23%), Positives = 129/346 (37%), Gaps = 38/346 (10%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TPLPVILGHEAAGIVESVGEG 80 FS H+V++K++ G C D + T P +LGHE G V VG Sbjct: 30 FSPFNFSRRATGEHDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSK 89 Query: 81 VTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIH 139 V K GDKV + I CGKC +C N NYC + + Sbjct: 90 VQKFKVGDKVGVASIIETCGKCEMCTNEVENYCPEAGSIDS------------------- 130 Query: 140 HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF 199 S V++EN V + PL+ + C T Y PG + Sbjct: 131 ---NYGACSNIAVINENFVIRWPENLPLDSGVPLLCAGITAYSPMKRYGLDKPGKRIGIA 187 Query: 200 GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMT 259 GLGG+G A+ KA GA + K K ++ GA + + ++ + Sbjct: 188 GLGGLGHVALRFAKAFGAKVTVISSSLKKKREAFEKFGADSFLVSSNPEE------MQGA 241 Query: 260 DGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAI 319 G +D + I ++ LL + G +I+G P + P LL+ G+ + Sbjct: 242 AGTLDGIIDTIPGNHSLE-PLLALLKPLGKLIILGAPEMPFEVPA-PSLLMGGKVMAAST 299 Query: 320 LGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 G K + + +F A+ + + V+ + +N + L + Sbjct: 300 AGSMKEIQE----MIEFAAEHNIVADV--EVISIDYVNTAMERLDN 339 >6DKH-A nrPDB Length = 346 Score = 201 bits (512), Expect = 3e-52, Method: Composition-based stats. Identities = 77/343 (22%), Positives = 129/343 (37%), Gaps = 35/343 (10%) Query: 38 RIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPL 93 +++ GICG+D H G + P++LGHE G V + + + G V Sbjct: 34 LVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAIN 91 Query: 94 AIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVV 153 CG C+ C N C RF H F++Y +V Sbjct: 92 PSKPCGHCKYCIEHNENQCTD--------------MRFFGSAMYFPHVD--GGFTRYKMV 135 Query: 154 DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCK 213 + + A + EKV + +A ++ G + G+G +G + K Sbjct: 136 ETSQCVPYPAKAD-EKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVK 193 Query: 214 AAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRL 273 GAA I+ D++ + KE+GA +NPQ+ + K G D SFEV G Sbjct: 194 TLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEK----GYFDVSFEVSGHP 249 Query: 274 DTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLV 333 ++ L A G V VG+ ++ PM+ L G+ ++ G F+ V Sbjct: 250 SSVNTCLEVT-RARGVMVQVGM---GGAMAEFPMMTLIGKEI--SLRGSFRFTSEFNTAV 303 Query: 334 ADFMAKKFSLDALITHVLPFEKINEGFDLL-HSGKSIRTILMF 375 + + L++ PF + E ++ + L+F Sbjct: 304 SWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF 346 >1YB5-A nrPDB Length = 351 Score = 200 bits (508), Expect = 8e-52, Method: Composition-based stats. Identities = 79/385 (20%), Positives = 148/385 (38%), Gaps = 66/385 (17%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSIE---EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT 57 M+T K+++ A ++E P ++ ++ V PK H+V IK+ A G+ + ++ SGT Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 58 MVTP--LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKN 115 LP G + AG++E+VG Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVG------------------------------------- 103 Query: 116 DVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175 D S F + +++Y + ++ V K+ ++ IG Sbjct: 104 ----------DNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGAAIGI 153 Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK 234 + T Y + ++ A V G + V G GGVGL+A +A G +I+ ++ Sbjct: 154 PYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYG-LKILGTAGTEEGQKIVL 212 Query: 235 ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 + GA E N ++ I ++ K + + G+D E++ ++ L G ++VG Sbjct: 213 QNGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANVNLSKD--LSLLSHGGRVIVVG 269 Query: 295 VPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAK--KFSLDALITHVLP 352 + +NP + + + +KE + A A L +I P Sbjct: 270 ---SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYP 326 Query: 353 FEKINEGFDLL--HSGKSIRTILMF 375 EK+ E + + SG + + IL+ Sbjct: 327 LEKVAEAHENIIHGSGATGKMILLL 351 >5VKT-A nrPDB Length = 362 Score = 193 bits (489), Expect = 2e-49, Method: Composition-based stats. Identities = 82/346 (23%), Positives = 126/346 (36%), Gaps = 31/346 (8%) Query: 33 KAHEVRIKMVAVGICGTDDHVVSGTMVT-PLPVILGHEAAGIVESVGEGVTTVKPGDKV- 90 +V IK++ GIC TD HV+ PV+ GHE G+V VG GVT K GD V Sbjct: 33 GDADVTIKVLFCGICHTDLHVIKNEWGNAMYPVVPGHEVVGVVTDVGHGVTKFKAGDTVG 92 Query: 91 IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQY 150 + + C C C NYC D H FS Sbjct: 93 VGYFVDSCRTCESCSTGHENYCP------------DLVLTSNGVDHHHHGATTKGGFSDV 140 Query: 151 TVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIM 210 VV ++ V ++ + PL+ + C T Y A PG V GLGG+G A+ Sbjct: 141 LVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMAQYALNEPGKHLGVVGLGGLGHMAVK 200 Query: 211 GCKAAGAARIIAVDINKDKFAKAK-ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV 269 KA G + + + K +A LGA + D + +D + Sbjct: 201 FAKAFGM-TVTVISSSPGKRDEALGRLGADAFLVSHDAAQMKAAAAT------LDGIIDT 253 Query: 270 IGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECV 329 + ++ LL + G V+VG P L ++ G+ G +G + + Sbjct: 254 VSAGHQIV-PLLALLKPMGQMVVVGAPSTPLELPAYAIIT-GGKRVAGNGVGSVADCQAM 311 Query: 330 PKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMF 375 A + + A I V+ + +N + L +R + Sbjct: 312 LDF-----AGEHGVTADI-EVVQMDYVNTAIERLEK-NDVRYRFVI 350 >5H83-A nrPDB Length = 360 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 78/349 (22%), Positives = 130/349 (37%), Gaps = 40/349 (11%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TPLPVILGHEAAGIVESVGEG 80 FS ++V+ K++ G C D + + T P ++GHE G+V +G Sbjct: 27 FSPFNFSRRATGENDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSK 86 Query: 81 VTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIH 139 V K GDKV + + C KC +C N N C K + ++ H Sbjct: 87 VQKFKVGDKVGVGGFVGACEKCEMCVNGVENNCSKVESTDG------------------H 128 Query: 140 HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF 199 VV+E PL + C T Y PG + Sbjct: 129 FGNNFGGCCNIMVVNEKYAVVWPENLPLHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIA 188 Query: 200 GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI---NPQDYKKPIQEVLK 256 GLGG+G AI KA GA + K K ++ G + NP++ + Sbjct: 189 GLGGLGHLAIRFAKAFGAKVTLISSSVKKKREALEKFGVDSFLLNSNPEEMQGAY----- 243 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWK 316 G +D + + +++ L + G +I+GVP + + P LL+ G+ Sbjct: 244 ----GTLDGIIDTMPVAHSIV-PFLALLKPLGKLIILGVPEEPFEVPA-PALLMGGKLIA 297 Query: 317 GAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 G+ G K + + DF AK + + V+P + +N + + + Sbjct: 298 GSAAGSMKETQE----MIDFAAKHNIVADV--EVIPIDYLNTAMERIKN 340 >3UOG-A nrPDB Length = 363 Score = 187 bits (474), Expect = 9e-48, Method: Composition-based stats. Identities = 80/363 (22%), Positives = 134/363 (36%), Gaps = 37/363 (10%) Query: 17 ELKKPFSIE--EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL--PVILGHEAAG 72 E P ++ E V H++ ++ +AV + D V+ M L P + + +G Sbjct: 34 ETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSG 93 Query: 73 IVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 +VE+VG+ VT +PGD+VI P L+ GT R Sbjct: 94 VVEAVGKSVTRFRPGDRVISTFAPGW----------------------LDGLRPGTGRTP 131 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 G+ S+Y V+ E + + + C T + + V + Sbjct: 132 AYETLGGAHPGV--LSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRA 189 Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G V G GGV L + KA GA +I +++K +A LGA IN + + ++ Sbjct: 190 GDRVVVQGTGGVALFGLQIAKATGA-EVIVTSSSREKLDRAFALGADHGINRLE-EDWVE 247 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTG 312 V D G D E+ G + L G ++GV + LLL Sbjct: 248 RVYALTGDRGADHILEIAGGAG--LGQSLKAVAPDGRISVIGVLEGFEVSGPVGPLLLKS 305 Query: 313 RTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTI 372 +G +G ++ E + V + L +I F ++ E L G + + Sbjct: 306 PVVQGISVGHRRALEDLVGAVD-----RLGLKPVIDMRYKFTEVPEALAHLDRGPFGKVV 360 Query: 373 LMF 375 + F Sbjct: 361 IEF 363 >1Q1N-A nrPDB Length = 360 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 84/370 (22%), Positives = 143/370 (38%), Gaps = 35/370 (9%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT-PLPVILGHEA 70 A E K + + P H++ IK+ A G+CG+D H +G +P+++GHE Sbjct: 11 AIQSHEDWKNPKKTKYDPKPFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEI 70 Query: 71 AGIVESVGEGV-TTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGT 128 G V +G + +K G +V + + C +C CKN YC K + Q +DG Sbjct: 71 VGKVVKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQ-PYEDG- 128 Query: 129 SRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA 188 ++ ++ Y V E+ V I P + CG T Y V Sbjct: 129 ------------YVSQGGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNG 176 Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK 248 PG + GLGG+G + KA GA + + + K A ++GA I + Sbjct: 177 C-GPGKKVGIVGLGGIGSMGTLISKAMGAETYV-ISRSSRKREDAMKMGADHYIATLEEG 234 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL-CCHEACGTSVIVGVPPDSQNLSMNPM 307 ++ D L + +++ + G V + +P + LS+ P Sbjct: 235 DWGEKYF-----DTFDLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPY 289 Query: 308 LLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEK--INEGFDLLHS 365 L + + LG K + KLV++ K + LP + ++E F+ + Sbjct: 290 GL-KAVSISYSALGSIKELNQLLKLVSEKDIK------IWVETLPVGEAGVHEAFERMEK 342 Query: 366 GKSIRTILMF 375 G +R Sbjct: 343 G-DVRYRFTL 351 >4Y1B-A nrPDB Length = 425 Score = 178 bits (452), Expect = 3e-45, Method: Composition-based stats. Identities = 83/409 (20%), Positives = 150/409 (36%), Gaps = 72/409 (17%) Query: 1 MSTAGKVIKCKAAVLWELKKP---FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT 57 + TA K + +P F E V+V P +V +K++A G+ + V Sbjct: 34 LGTAPKQMYASLIRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNN---VWAA 90 Query: 58 MVTPLPVIL--------------GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRI 103 + PL VI G + +GIV +VG+GV +KPG +V+ LA Sbjct: 91 LGEPLDVIAARQKQGATEDFHIGGSDLSGIVWAVGDGV-RLKPGAEVVVLA--------- 140 Query: 104 CKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDA 163 C+ ES D+ + T R + +F+Q+ VVDE Sbjct: 141 CRWDES----AQDIRLGADPVTSSTQRVWGYEE------NYGSFAQFAVVDEYMCHPKPQ 190 Query: 164 ASPLEKVCLIGCGFSTGYGSAVNV--AKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARI 220 +T Y V PG ++ G GG+G AI + G + Sbjct: 191 RLSWAAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPV 250 Query: 221 IAVDINKDKFAKAKELGATECINPQDYKKP-------IQEVLKEMTDGGVDFS---FEVI 270 V ++++ LGA I+ +++ +E +K+ DG F +EV+ Sbjct: 251 AVV-SSEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFWEVL 309 Query: 271 G------------RLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGA 318 G DT+ S+ A + G + ++ + + + R +G+ Sbjct: 310 GERRAPRIVLEHSGADTIPTSIYMADNAGMVVICGGTTGYNGDVDLRFLWMRQKR-LQGS 368 Query: 319 ILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 + + +L+ + ++D ++ FE+I L+H + Sbjct: 369 HAASAREAREITRLID-----QGAIDPCLSRTFGFEEIGLAHQLIHDNQ 412 >2DPH-A nrPDB Length = 398 Score = 177 bits (449), Expect = 6e-45, Method: Composition-based stats. Identities = 93/396 (23%), Positives = 151/396 (38%), Gaps = 46/396 (11%) Query: 13 AVLWELKKPFSIEEVEVAPPK------AHEVRIKMVAVGICGTDDHVVSGTMVTPLPVIL 66 +V++ + +E V + H V +K+V+ ICG+D H+ G + P +L Sbjct: 5 SVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPKGHVL 64 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 GHE G V G V + GD V CG+CR CK S+ C N V+ Sbjct: 65 GHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPDADL--- 121 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVV---DENAVAKIDAASPLEKV---CLIGCGFSTG 180 G F + ++Y +V D + D +EK+ LI TG Sbjct: 122 GAFGFDLKGWS-------GGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPTG 174 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG--A 238 + V+ A V PGS + G G VG A G + GAA +I D N ++ + G Sbjct: 175 FHGCVS-AGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFET 233 Query: 239 TECINPQDYKKPIQEVL-KEMTDGGVD-FSFEVIG--------RLDTMMASLLCCHEACG 288 + N + I ++L K D GVD FE G + + SL A G Sbjct: 234 IDLRNSAPLRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAGG 293 Query: 289 TS----VIVGVPPD--SQNLSMNPMLLLTGRTWKGA--ILGGFKSKECVPK---LVADFM 337 + VG PD +++ + L G+ W + I+ G + + Sbjct: 294 AIGIPGIYVGSDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYNRHLTEAILWD 353 Query: 338 AKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTIL 373 + + V+ ++ +G+ G + ++ Sbjct: 354 QMPYLSKVMNIEVITLDQAPDGYAKFDKGSPAKFVI 389 >3QWB-A nrPDB Length = 334 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 80/363 (22%), Positives = 125/363 (34%), Gaps = 65/363 (17%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGV 81 E+ V E+ IK G+ + + G P +LG EA+G V + G+GV Sbjct: 23 IKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGV 82 Query: 82 TTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHF 141 T + GD+V + Sbjct: 83 TNFEVGDQVA-------------------------------------------------Y 93 Query: 142 LGISTFSQYT-VVDENAVAKIDAASPLEKVCLIGCGFS---TGYGSAVNVAKVTPGSTCA 197 + STF+QY+ + + V K+ + E++ L G T V G Sbjct: 94 ISNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVL 153 Query: 198 VFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 +F GGVGL K GA IAV +K AKE GA IN + +++VLK Sbjct: 154 LFAAAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINASK-EDILRQVLK 211 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS-QNLSMNPMLLLTGRTW 315 GVD SF+ +G+ DT SL + G V G S+ + Sbjct: 212 FTNGKGVDASFDSVGK-DTFEISL-AALKRKGVFVSFGNASGLIPPFSITRLSPKNITLV 269 Query: 316 KGAILGGFKSKECVPKLVADFM----AKKFSLDALITHVLPFEKINEGFDLLHSGKSIRT 371 + + G E +F +KK ++ I P + S K++ Sbjct: 270 RPQLYGYIADPEEWKYYSDEFFGLVNSKKLNIK--IYKTYPLRDYRTAAADIESRKTVGK 327 Query: 372 ILM 374 +++ Sbjct: 328 LVL 330 >3WLE-A nrPDB Length = 341 Score = 171 bits (433), Expect = 5e-43, Method: Composition-based stats. Identities = 87/353 (24%), Positives = 147/353 (41%), Gaps = 46/353 (13%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVK 85 ++ V PKA ++ +K+ AVG+C +D HV+ + ++GHE AG V +VG+ V K Sbjct: 28 DLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGTVAAVGDDVINYK 87 Query: 86 PGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGIS 145 GD+V + CG C+ C+ N C KN + G DG Sbjct: 88 VGDRVACVGPNGCGGCKYCRGAIDNVC-KNAFGDWFGLGYDG------------------ 128 Query: 146 TFSQYTVV-DENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGV 204 + QY +V +++I + T Y A+ +A+V+P S + G GG+ Sbjct: 129 GYQQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPYH-AIKMAQVSPTSNILLIGAGGL 187 Query: 205 GLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVD 264 G +AI KA GA ++ +D K+ +AK+LGA + E L E G Sbjct: 188 GGNAIQVAKAFGA-KVTVLDKKKEARDQAKKLGAD----------AVYETLPESISPG-- 234 Query: 265 FSFEVIGRLDTMMASLLCCHE---ACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILG 321 SF ++ A+ C + G + VG+ + + ++ L L G+ G Sbjct: 235 -SFSACFDFVSVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLGD-LALREIRILGSFWG 292 Query: 322 GFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGK-SIRTIL 373 + V KLV++ K + +++ E + L + R + Sbjct: 293 TTNDLDDVLKLVSEGKVKP------VVRSAKLKELPEYIEKLRNNAYEGRVVF 339 >1WLY-A nrPDB Length = 333 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 81/383 (21%), Positives = 140/383 (36%), Gaps = 75/383 (19%) Query: 12 AAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT----MVTPLPVI 65 AAV+ + P F EEV+V P +VR++ A+G+ D + +G +V P++ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPPIV 63 Query: 66 LGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 +G EAA +VE VG GVT G++V C P Sbjct: 64 VGFEAAAVVEEVGPGVTDFTVGERVCT-----------CLPP------------------ 94 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCG--FSTGYGS 183 + +SQ + + K+ L+ V L G T Sbjct: 95 ------------------LGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQYL 136 Query: 184 AVNVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 KV PG + GG+G + + GA +I ++K A++LG I Sbjct: 137 LHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGA-TVIGTVSTEEKAETARKLGCHHTI 195 Query: 243 NPQDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 N + EV++E+T G GVD ++ IG+ DT+ SL C G G + Sbjct: 196 NYS--TQDFAEVVREITGGKGVDVVYDSIGK-DTLQKSLDCL-RPRGMCAAYGHASGVAD 251 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADF---------MAKKFSLDALITHVLP 352 P+ ++ +G++ + ++ K L + + P Sbjct: 252 ----PIRVVEDLGVRGSLFITRPALWHYMSNRSEIDEGSKCLFDAVKAGVLHSSVAKTFP 307 Query: 353 FEKINEGFDLLHSGKSIRTILMF 375 + + ++I +I++ Sbjct: 308 LREAAAAHKYMGGRQTIGSIVLL 330 >4JLW-A nrPDB Length = 399 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 90/393 (22%), Positives = 157/393 (39%), Gaps = 52/393 (13%) Query: 20 KPFSIEEVEVAPPK---------AHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEA 70 P +E + PK H V +++V+ ICG+D H+V G P ++LGHE Sbjct: 11 GPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEI 70 Query: 71 AGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSR 130 G V +G GV T+K GD V CG CR CK + CL + + G Sbjct: 71 TGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPARAGGAY------ 124 Query: 131 FTCRRKPIHHFLGISTFSQYTVV---DENAVAKIDAASPLEKVCLIGC---GFSTGYGSA 184 + + ++Y +V D N + + + +EK+ + C TGY A Sbjct: 125 -----GYVDMGGWVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGA 179 Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 V A V PGST + G G VGL+A + GAA +I D+N + A AK+ G Sbjct: 180 V-TAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLS 238 Query: 245 QDYKKPIQEVLKEMTDGGVDFSFEVIG--------------RLDTMMASLLCCHEACGTS 290 +D +++ + + VD + + +G T++ SL+ G Sbjct: 239 KDTPL-HEQIAALLGEPEVDCAVDAVGFEARGHGHSGSQQEAPATVLNSLMGITRVAGKI 297 Query: 291 VIVGVPPDSQNLSMN------PMLLLTGRTWKGA---ILGGFKSKECVPKLVADFMAKKF 341 I G+ +++ + + G W + G + +L+ M + Sbjct: 298 GIPGLYVTEDPGAVDAAAKHGALSIRFGLGWAKSHSFHTGQTPVMKYNRQLMQAIMWDRI 357 Query: 342 SLDALI-THVLPFEKINEGFDLLHSGKSIRTIL 373 + ++ V+ + +G+ +G + ++ Sbjct: 358 KIADIVGVEVITLDDAPKGYGEFDAGVPKKFVI 390 >6C49-A nrPDB Length = 350 Score = 162 bits (409), Expect = 3e-40, Method: Composition-based stats. Identities = 69/369 (18%), Positives = 133/369 (36%), Gaps = 39/369 (10%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM-VTPLPVILG 67 +A + + + + + H+V +K+ G+C +D V++ T PV+ G Sbjct: 13 TIQAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAG 72 Query: 68 HEAAGIVESVGEGVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 HE G + ++G ++ G +V I C C C + C +++ G Sbjct: 73 HEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIATIVG---- 128 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 F+ + E + CG T + + Sbjct: 129 ----------------HAGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLK 172 Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246 K+ V G+GG+G AI KA G I A N DK + K +GA +N +D Sbjct: 173 H-KIQATHHVGVIGIGGLGHIAIKLLKAWG-CEITAFSSNPDKTEELKAMGADHVVNSRD 230 Query: 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 + + G D + + + + G+ +G+ + +S+ Sbjct: 231 TEAVKAQ------KGKFDLLLSTV-NVTLNWRAFISTLAPNGSLHFLGLTLEPVPVSVG- 282 Query: 307 MLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 366 L+ ++ G+ G + + K A + + I + P ++NE + LHSG Sbjct: 283 SLIDGAKSVTGSPTGSPAALRQLLKF-----AARKKIAPQI-ELFPMSQLNEAIERLHSG 336 Query: 367 KSIRTILMF 375 ++ R ++ Sbjct: 337 QA-RYRIVL 344 >1KOL-A nrPDB Length = 398 Score = 159 bits (403), Expect = 1e-39, Method: Composition-based stats. Identities = 89/396 (22%), Positives = 155/396 (39%), Gaps = 48/396 (12%) Query: 14 VLWELKKPFSIEEVEVAPPKA-------HEVRIKMVAVGICGTDDHVVSGTMVTPLPVIL 66 V++ +++++ + H V +K+V+ ICG+D H+V G + ++L Sbjct: 6 VVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGLVL 65 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 GHE G V G V ++ GD V CG+CR CK + CL + + G Sbjct: 66 GHEITGEVIEKGRDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPARAGGAY-- 123 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVV---DENAVAKIDAASPLEKVCLIGC---GFSTG 180 + ++Y +V D N + D +EK+ + C TG Sbjct: 124 ---------GYVDMGDWTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTG 174 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG--- 237 Y AV A V PGST V G G VGL+A + GAA +I D+N + A AK G Sbjct: 175 YHGAV-TAGVGPGSTVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEI 233 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVD-FSFEVIGR---------LDTMMASLLCCHEAC 287 A ++ +++ + + D VD FE G T++ SL+ Sbjct: 234 ADLSLDTPLHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVA 293 Query: 288 GTSVIVGVPPDSQNLSMNP------MLLLTGRTWKGA---ILGGFKSKECVPKLVADFMA 338 G I G+ +++ + + G W + G + L+ M Sbjct: 294 GKIGIPGLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMW 353 Query: 339 KKFSLDALI-THVLPFEKINEGFDLLHSGKSIRTIL 373 + ++ ++ V+ + G+ +G + ++ Sbjct: 354 DRINIAEVVGVQVISLDDAPRGYGEFDAGVPKKFVI 389 >3B70-A nrPDB Length = 371 Score = 151 bits (381), Expect = 5e-37, Method: Composition-based stats. Identities = 67/368 (18%), Positives = 115/368 (31%), Gaps = 68/368 (18%) Query: 23 SIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVT 82 +V +++ AV I +D + G TP LG + AG V +VG VT Sbjct: 25 VWNAAPCPMLPRDQVYVRVEAVAINPSDTKMR-GQFATPW-AFLGTDYAGTVVAVGSDVT 82 Query: 83 TVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFL 142 ++ GD+V C Sbjct: 83 HIQVGDRVYGAQNEMC----------------------------------------PRTP 102 Query: 143 GISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP---------- 192 FSQYTV AKI E+ + G ST + + P Sbjct: 103 DQGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTAGLAMKLLGLPLPSPSADQPPTH 162 Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDI-NKDKFAKAKELGATECINPQDYKKPI 251 V GG +A + + + I + + F AK GA E + + + Sbjct: 163 SKPVYVLVYGGSTATATVTMQMLRLSGYIPIATCSPHNFDLAKSRGAEEVFDYRAPN--L 220 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD--------SQNLS 303 + ++ T + ++ + I +++ A G V + P+ + + + Sbjct: 221 AQTIRTYTKNNLRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMVTTDWT 280 Query: 304 MNPMLLLTGRTWKGAILGGFKSKECVPKLVADF--MAKKFSLDALITHVLPFEKINEGFD 361 + P + G TW G E + D +A + D + H P + GFD Sbjct: 281 LGPTIFGEGSTWPAPY--GRPGSEEERQFGEDLWRIAGQLVEDGRLVH-HPLRVVQGGFD 337 Query: 362 LLHSGKSI 369 + G + Sbjct: 338 HIKQGMEL 345 >2CF5-A nrPDB Length = 357 Score = 151 bits (380), Expect = 7e-37, Method: Composition-based stats. Identities = 79/362 (21%), Positives = 135/362 (37%), Gaps = 31/362 (8%) Query: 15 LWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV-TPLPVILGHEAAGI 73 + S + +V I+++ GIC TD H + + P++ GHE G Sbjct: 15 ARDPSGILSPYTYTLRETGPEDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVVGE 74 Query: 74 VESVGEGVTTVKPGDKVIPLAIPQCGKCR-ICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 V VG V+ GD V + C C+ YC K S Sbjct: 75 VVEVGSDVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSY------------- 121 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 I+ F++ TVV + V KI +E+ + C T Y + P Sbjct: 122 -NDVYINGQPTQGGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQP 180 Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + GLGGVG + KA G + NK + ++LGA + + D Q Sbjct: 181 GLRGGILGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYVIGSD-----Q 235 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTG 312 + E+ D +D+ + + + L + G +++GV + + P+L+L Sbjct: 236 AKMSELADS-LDYVIDTVPVHHALEPYL-SLLKLDGKLILMGVINNPLQF-LTPLLMLGR 292 Query: 313 RTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTI 372 + G+ +G K E + +F +K I V+ + +N F+ L +R Sbjct: 293 KVITGSFIGSMKETEE----MLEFCKEKGLSS--IIEVVKMDYVNTAFERLEK-NDVRYR 345 Query: 373 LM 374 + Sbjct: 346 FV 347 >3FBG-A nrPDB Length = 346 Score = 150 bits (379), Expect = 8e-37, Method: Composition-based stats. Identities = 58/291 (19%), Positives = 99/291 (34%), Gaps = 58/291 (19%) Query: 19 KKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVG 78 F +++ PK HE+ +K+ ++ + D V+ P +LG +A G+VESVG Sbjct: 17 GNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMD-VSKAPRVLGFDAIGVVESVG 75 Query: 79 EGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPI 138 VT GD V P Sbjct: 76 NEVTMFNQGDIVYYSGSPD----------------------------------------- 94 Query: 139 HHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVT------P 192 + ++Y +++E VAK E+ + T Y + +V ++ Sbjct: 95 ----QNGSNAEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFGISRNRNENE 150 Query: 193 GSTCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G T + G GGVG A KA G R+I + K++GA +N ++ + Sbjct: 151 GKTLLIINGAGGVGSIATQIAKAYG-LRVITTASRNETIEWTKKMGADIVLNHKE---SL 206 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 K VD+ F D ++ + G + + Q+L Sbjct: 207 LNQFKTQGIELVDYVF-CTFNTDMYYDDMIQLVKPRGHIATIVAFENDQDL 256 >2VCY-A nrPDB Length = 344 Score = 150 bits (379), Expect = 9e-37, Method: Composition-based stats. Identities = 78/383 (20%), Positives = 138/383 (36%), Gaps = 67/383 (17%) Query: 9 KCKAAVLWELKKP---FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV--TPLP 63 + +A V P ++ +E+A + +VR+KM+A I +D +++ G LP Sbjct: 13 RVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELP 72 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGT 123 + G+E V +VG VT +KPGD VIP Sbjct: 73 AVGGNEGVAQVVAVGSNVTGLKPGDWVIPANA---------------------------- 104 Query: 124 LQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 G+ T+ V E A+ ++ + PL+ +G T Y Sbjct: 105 -------------------GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRM 145 Query: 184 AVNVAKVTPGSTCA-VFGLGGVGLSAIMGCKAAGAARIIAVDINKD--KF-AKAKELGAT 239 ++ ++ PG + GVG + I A G I V D K + K LGA Sbjct: 146 LMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAE 205 Query: 240 ECINPQDYKKP-IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD 298 I ++ ++P ++ K+M + +G + LL GT V G Sbjct: 206 HVITEEELRRPEMKNFFKDMPQP--RLALNCVGGKSSTE--LLRQLARGGTMVTYGGMAK 261 Query: 299 SQNLSMNPMLLLTGRTWKGAILGGFK---SKECVPKLVADF--MAKKFSLDALITHVLPF 353 ++ +L+ +G L +K S + +L+ + ++ L A +P Sbjct: 262 QPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPL 321 Query: 354 EKINEGFDL-LHSGKSIRTILMF 375 + + + S + IL Sbjct: 322 QDYQSALEASMKPFISSKQILTM 344 >4RVS-A nrPDB Length = 329 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 70/381 (18%), Positives = 123/381 (32%), Gaps = 73/381 (19%) Query: 12 AAVLWELKKPFSIEEVEVAPPKAH--EVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHE 69 A + E P + V+ P+ E+ IK A+G+ D + SG LP ++G E Sbjct: 4 AIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSE 63 Query: 70 AAGIVESVGEGVTT----VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 G VE+VG GVT + GD+V+ Sbjct: 64 VCGTVEAVGPGVTAADTAISVGDRVVSA-------------------------------- 91 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 185 ++++ + AK+ E T + Sbjct: 92 ----------------SANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLK 135 Query: 186 NVAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 244 +V V G T V G GGVGL G R+I +K +K+ GA ++ Sbjct: 136 SVYPVKRGDTVLVHAGAGGVGLILTQWATHLGV-RVITTVSTAEKAKLSKDAGADVVLDY 194 Query: 245 QDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLS 303 + ++E+T G GV ++ +G T + L GT + G Sbjct: 195 PEDAWQFAGRVRELTGGTGVQAVYDGVGA--TTFDASLASLAVRGTLALFGAASGPVP-P 251 Query: 304 MNPMLLLTGRTWKGAILGGFKSKECVPKLVADF---MAKKFS------LDALITHVLPFE 354 ++P G++ S + +F A+ F + + P Sbjct: 252 VDP----QRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGNEAITVAVGGRYPLA 307 Query: 355 KINEGFDLLHSGKSIRTILMF 375 L + K++ ++++ Sbjct: 308 DALRAHQDLEARKTVGSVVLL 328 >1QOR-A nrPDB Length = 327 Score = 145 bits (365), Expect = 3e-35, Method: Composition-based stats. Identities = 84/361 (23%), Positives = 132/361 (36%), Gaps = 63/361 (17%) Query: 16 WELKKPFSIEEVEVAP--PKAHEVRIKMVAVGICGTDDHVVSGTMVTP-LPVILGHEAAG 72 + P ++ VE P P +E++++ A+GI D ++ SG P LP LG EAAG Sbjct: 8 HKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAG 67 Query: 73 IVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 IV VG GV +K GD+V+ Sbjct: 68 IVSKVGSGVKHIKAGDRVV----------------------------------------- 86 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192 + + +S + + A + AA E+ T Y ++ P Sbjct: 87 ------YAQSALGAYSSVHNIIADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKP 140 Query: 193 GSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 GGVGL A KA GA ++I K A + GA + IN ++ + + Sbjct: 141 DEQFLFHAAAGGVGLIACQWAKALGA-KLIGTVGTAQKAQSALKAGAWQVINYRE--EDL 197 Query: 252 QEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN------LSM 304 E LKE+T G V ++ +GR DT SL C G V G + L+ Sbjct: 198 VERLKEITGGKKVRVVYDSVGR-DTWERSLDCLQRR-GLMVSFGNSSGAVTGVNLGILNQ 255 Query: 305 NPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLH 364 L +T + +G I + E +L + + +D P + ++L Sbjct: 256 KGSLYVTRPSLQGYITTREELTEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILE 315 Query: 365 S 365 S Sbjct: 316 S 316 >3HZZ-A nrPDB Length = 467 Score = 144 bits (364), Expect = 4e-35, Method: Composition-based stats. Identities = 73/392 (18%), Positives = 131/392 (33%), Gaps = 71/392 (18%) Query: 20 KPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHV-------------VSGTMVT-----P 61 K ++EV V E + ++A + G + Sbjct: 74 KSIHLDEVPVPELGPGEALVAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTKRHD 133 Query: 62 LPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 LP I+G + AG+V G GV +PGD+V+ +CL ++ +P Sbjct: 134 LPYHIIGSDLAGVVLRTGPGVNAWQPGDEVVA------------------HCLSVELESP 175 Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180 G + ++ ++ +V N + E+ G ST Sbjct: 176 DGHDD---TMLDPEQRIWGFETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTA 232 Query: 181 YGSAV--NVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 Y V N A + G ++G GG+G A AG A I V + K + +G Sbjct: 233 YRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFA-LAGGANPICVVSSPQKAEICRSMG 291 Query: 238 ATECI----------------NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL 281 A I +P+++K+ + + + +D FE GR +T AS+ Sbjct: 292 AEAIIDRNAEGYKFWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPGR-ETFGASVY 350 Query: 282 CCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKF 341 + GT + N L ++ + G+ ++ +L+A K Sbjct: 351 VTRK-GGTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAYEANRLIA-----KG 404 Query: 342 SLDALITHVLPFEKINEG----FDLLHSGKSI 369 + ++ E+ + LH GK Sbjct: 405 KIHPTLSKTYSLEETGQAAYDVHRNLHQGKVG 436 >3JYN-A nrPDB Length = 325 Score = 135 bits (339), Expect = 3e-32, Method: Composition-based stats. Identities = 71/366 (19%), Positives = 122/366 (33%), Gaps = 62/366 (16%) Query: 19 KKPFSIEEVEVAP--PKAHEVRIKMVAVGICGTDDHVVSGTMVTP-LPVILGHEAAGIVE 75 P +E V+ P P V ++ A+G+ D + SG P LP LG E AG+VE Sbjct: 11 GGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVVE 70 Query: 76 SVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRR 135 +VG+ VT RF Sbjct: 71 AVGDEVT-----------------------------------------------RFKVGD 83 Query: 136 KPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGST 195 + + + +S+ V+ E + K+ + E+ + T +V PG Sbjct: 84 RVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQYLLRQTYQVKPGEI 143 Query: 196 CAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 GGVG A KA GA ++I + +K A AK LGA E I+ ++ + V Sbjct: 144 ILFHAAAGGVGSLACQWAKALGA-KLIGTVSSPEKAAHAKALGAWETIDYS-HEDVAKRV 201 Query: 255 LKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRT 314 L+ ++ +G DT + SL +++ + Sbjct: 202 LELTDGKKCPVVYDGVG-QDTWLTSLDSVAPRGLVVSFGNASGPVSGVNLGILAQKDSVY 260 Query: 315 WKGAILGGFKS-----KECVPKLVADFMAKKFSLDALITHVLPFEKINEG-FDLLHSGKS 368 LG + + + +L + K +D + + + +L + Sbjct: 261 VTRPTLGSYANNAQNLQTMADELFDMLASGKLKVDGI--EQYALKDAAKAQIELSARRTT 318 Query: 369 IRTILM 374 TIL+ Sbjct: 319 GSTILI 324 >2OBY-A nrPDB Length = 338 Score = 134 bits (338), Expect = 4e-32, Method: Composition-based stats. Identities = 75/369 (20%), Positives = 124/369 (33%), Gaps = 65/369 (17%) Query: 19 KKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPV--ILGHEAAGIVES 76 + ++EV P EV +K+ A + D G P ILG EA+G V Sbjct: 18 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAE 77 Query: 77 VGEGVT-TVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRR 135 +G G K GD + L Sbjct: 78 LGPGCQGHWKIGDTAMAL------------------------------------------ 95 Query: 136 KPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGST 195 L +QY V E + I L + I + T + V V G Sbjct: 96 ------LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDY 149 Query: 196 CAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + GL GVG +AI + AGA + ++ K A++LGA N + + + Sbjct: 150 VLIHAGLSGVGTAAIQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKK-EDFSEAT 207 Query: 255 LKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ-NLSMNPMLLLTGR 313 LK GV+ + IG + + C G V+ G+ N + LL Sbjct: 208 LKFTKGAGVNLILDCIGG--SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRG 265 Query: 314 TWKGAILGGF--KSKECVPKLVADFMAKKFSLD------ALITHVLPFEKINEGFDLLHS 365 + ++L K K+ + + + FS + ++ + P +I E + + Sbjct: 266 SLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 325 Query: 366 GKSIRTILM 374 K+I I++ Sbjct: 326 NKNIGKIVL 334 >4J6F-A nrPDB Length = 382 Score = 129 bits (324), Expect = 2e-30, Method: Composition-based stats. Identities = 67/385 (17%), Positives = 120/385 (31%), Gaps = 62/385 (16%) Query: 12 AAVLWELKKPFSI---EEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP------- 61 A +L + +V V P A EV IK+ A G+ TD V G T Sbjct: 36 AVLLTGHGGLEKLVYSRDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVS 95 Query: 62 ----------LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNY 111 P I G + G + +VGEGV + G++V+ Y Sbjct: 96 TWRRHGNTLTFPRIQGTDTVGHIVAVGEGVDRARIGERVMVDFSI--------------Y 141 Query: 112 CLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVC 171 +D + G +++Y + + ++ Sbjct: 142 NRDDDSLADIDYMGHGR---------------DGGYAEYMALPAENAHVVATDLTDIELA 186 Query: 172 LIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKF 230 C + TG + A++ G T V G GGVG + I +A GA I K Sbjct: 187 TFCCAYLTG-ERMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAG--PGKE 243 Query: 231 AKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 A ++GA + + + V +D +++G + LL G Sbjct: 244 AAMLDIGAQAVV-TRGQGDLAEAVEAASGGRPIDVVADLVGGP--LFNDLLKILRPEGRY 300 Query: 291 VIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHV 350 G + L G+ G + + + ++ + L+ V Sbjct: 301 TTAGAIAGPVVQLDLRTMYLKQLELHGSSQGSRADFRRLVRYI-----EEKKIRPLVGGV 355 Query: 351 LPFEKINEG-FDLLHSGKSIRTILM 374 P + + D + + +++ Sbjct: 356 YPLSEFHRAQTDFMAKNFVGKLVVV 380 >4A10-A nrPDB Length = 447 Score = 128 bits (322), Expect = 4e-30, Method: Composition-based stats. Identities = 68/387 (17%), Positives = 119/387 (30%), Gaps = 67/387 (17%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGT----------------DDHVV 54 K +++K + EV + EV + ++A I + Sbjct: 39 KGVADKDVRKSLRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNAR 98 Query: 55 SGTMVTPLP---VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNY 111 G T +LG + +G+V G GV KPGD VI Sbjct: 99 QGGWATRHDQPYHVLGSDCSGVVVRTGIGVRRWKPGDHVIVHPA---------------- 142 Query: 112 CLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVC 171 + Q G ++ ++Y VV + + A E+ Sbjct: 143 -----HVDEQEPATHGDGMLGTEQRAWGFETNFGGLAEYGVVRASQLLPKPAHLTWEEAA 197 Query: 172 LIGCGFSTGYGSAV--NVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKD 228 + T Y V A++ G ++G GG+G AI K G + V + Sbjct: 198 VSPLCAGTAYRMLVSDRGAQMKQGDIVLIWGASGGLGSYAIQFVKNGGGIPVAVV-SSAQ 256 Query: 229 KFAKAKELGATECINPQDY-------KKP---------IQEVLKEMTDGGVDFSFEVIGR 272 K A + LG IN + P + +++ E D FE GR Sbjct: 257 KEAAVRALGCDLVINRAELGITDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGR 316 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKL 332 + + GT V G + N L + + G+ + ++ +L Sbjct: 317 V--TFGLSVIVARRGGTVVTCGSSSGYLHTFDNRYLWMKLKKIVGSHGANHEEQQATNRL 374 Query: 333 VADFMAKKFSLDALITHVLPFEKINEG 359 + ++ ++ V P + E Sbjct: 375 F-----ESGAVVPAMSAVYPLAEAAEA 396 >4A27-A nrPDB Length = 349 Score = 123 bits (309), Expect = 1e-28, Method: Composition-based stats. Identities = 70/396 (17%), Positives = 128/396 (32%), Gaps = 87/396 (21%) Query: 8 IKCKAAVLWELKK--PFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL--P 63 ++ +A VL + + P+ E++I++ A G+ D V G + P P Sbjct: 2 MEMRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTP 61 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGT 123 ++ G E +GIVE++G+ V + GD+V+ +C E Y + +D Sbjct: 62 LVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDD------- 114 Query: 124 LQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + F T Y Sbjct: 115 -----------------------------------------MSFSEAAAFPMNFVTAYVM 133 Query: 184 AVNVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 VA + G + V GGVG + C + K K Sbjct: 134 LFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTAST-FKHEAIK----DSVT 188 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG----VPPD 298 + D + +K ++ GVD + + +T L + GT ++ G V + Sbjct: 189 HLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKG--LSLLKPLGTYILYGSSNMVTGE 246 Query: 299 SQNL-----------SMNPMLLL-TGRTWKGAILGGFKSKEC--------VPKLVADFMA 338 +++ +NP+ L + G L K+ V KL+ + Sbjct: 247 TKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQ 306 Query: 339 KKFSLDALITHVLPFEKINEGFDLLH-SGKSIRTIL 373 KK + ++ + E++ E +H G + IL Sbjct: 307 KK--IKPVVDSLWALEEVKEAMQRIHDRGNIGKLIL 340 >3SLK-A nrPDB Length = 795 Score = 122 bits (306), Expect = 2e-28, Method: Composition-based stats. Identities = 66/354 (18%), Positives = 108/354 (30%), Gaps = 59/354 (16%) Query: 22 FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGV 81 E AP EVRI M A G+ D + G P LG E AG+V G GV Sbjct: 226 LVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMY--PGVASLGSEGAGVVVETGPGV 283 Query: 82 TTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHF 141 T + PGD+V+ + Sbjct: 284 TGLAPGDRVMGMIPKA-------------------------------------------- 299 Query: 142 LGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-G 200 F V D V +I A + + F T Y + V++A + PG + V Sbjct: 300 -----FGPLAVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVDLAGLRPGESLLVHSA 354 Query: 201 LGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTD 260 GGVG++AI + GA + A +A EL + + Q+ L Sbjct: 355 AGGVGMAAIQLARHLGA-EVYATASEDK--WQAVELSREHLASSRTCDFE-QQFLGATGG 410 Query: 261 GGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAIL 320 GVD + + L G + +G + + + Sbjct: 411 RGVDVVLNSLAGE--FADASLRMLPRGGRFLELGKTDVRDPVEVADAHPGVSYQAFDTVE 468 Query: 321 GGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILM 374 G + + + + + L+ L + E L + + +++ Sbjct: 469 AGPQRIGEMLHELVELFEGRV-LEPLPVTAWDVRQAPEALRHLSQARHVGKLVL 521 >3TQH-A nrPDB Length = 321 Score = 121 bits (304), Expect = 4e-28, Method: Composition-based stats. Identities = 70/374 (18%), Positives = 124/374 (33%), Gaps = 72/374 (19%) Query: 11 KAAVLWELKKPFSIEEVEVAPPK--AHEVRIKMVAVGICGTDDHVVSG------TMVTPL 62 KA + P ++ V+ P+ +++ IK+ A + D +G + L Sbjct: 8 KAIQFDQFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVAKKLKNNL 67 Query: 63 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQG 122 P LG++ +G V +G V V GDKV+ +A C C Sbjct: 68 PSGLGYDFSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--C------------------ 107 Query: 123 TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 182 +++Y + + + + + T Sbjct: 108 ------------------------YAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTAL- 142 Query: 183 SAVNVAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A+N A+V G + G GGVG AI K G + +K A K LGA +C Sbjct: 143 QALNQAEVKQGDVVLIHAGAGGVGHLAIQLAKQKG--TTVITTASKRNHAFLKALGAEQC 200 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 IN + +L T VD +++G + + + C + G V V + Sbjct: 201 INYHEED----FLLAISTP--VDAVIDLVGGDVGIQS--IDCLKETGCIVSVPTITAGRV 252 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 + + + G K + + L I+ + + + Sbjct: 253 IEV-------AKQKHRRAFGLLKQFNIEELHYLGKLVSEDKLRIEISRIFQLSEAVTAHE 305 Query: 362 LLHSGKSIRTILMF 375 LL +G +R L+F Sbjct: 306 LLETGH-VRGKLVF 318 >4IDE-A nrPDB Length = 332 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 78/374 (20%), Positives = 127/374 (33%), Gaps = 77/374 (20%) Query: 11 KAAVLWELKKPFSI----EEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMV---TPLP 63 KA V E K + V V K +V IK+VA + D G +PLP Sbjct: 25 KAWVYSEYGKTSDVLKFDPSVAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLP 84 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGT 123 I G++ AG+V VG VT K GD+V Sbjct: 85 TIPGYDVAGVVVKVGSQVTKFKVGDEVYG------------------------------- 113 Query: 124 LQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + + + ++YT DE +A + + T Sbjct: 114 --------DLNETALVNPTRFGSLAEYTAADERVLAHKPKNLSFIEAASLPLAIETA-HE 164 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLS-AIMGCKA-AGAARIIAVDINKDKFAKAKELGATEC 241 + A+++ G + V G G + I K GA+++ A K K + LGA Sbjct: 165 GLERAELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKVAATASTK-KLDLLRTLGADLA 223 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQN 301 I+ +E +++ + D ++ +G D ++ E IVG Sbjct: 224 IDYT------KENFEDLPEK-FDVVYDAVGETD---KAVKAVKEGGKVVTIVG------- 266 Query: 302 LSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFD 361 P +L T KG++L KL + K T PF K+ E F Sbjct: 267 -PATPPAILFVLTSKGSVL---------EKLKPYLESGKVKPVLDPTSPYPFTKVVEAFG 316 Query: 362 LLHSGKSIRTILMF 375 L S ++ ++++ Sbjct: 317 YLESSRATGKVVVY 330 >2VN8-A nrPDB Length = 375 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 73/414 (17%), Positives = 131/414 (31%), Gaps = 95/414 (22%) Query: 1 MSTAGKVIKCKAAVLWELKKPFSI---EEVEVAPPK-AHEVRIKMVAVGICGTDDHVVSG 56 + T + A V+ + K + + + + +EV +K+ A + D ++ SG Sbjct: 13 LGTENLYFQSMAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSG 72 Query: 57 ----------------TMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGK 100 P+ LG + +G+V G V KPGD+V P Sbjct: 73 YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPW--- 129 Query: 101 CRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAK 160 T S++ VV N V+ Sbjct: 130 ------------------------------------------KQGTLSEFVVVSGNEVSH 147 Query: 161 IDAASPLEKVCLIGCGFSTGYGSAVNVAKV----TPGSTCAVFGL-GGVGLSAIMGCKAA 215 + + + T + + V + G + G GGVG AI KA Sbjct: 148 KPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAW 207 Query: 216 GAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDT 275 A + AV ++LGA + I+ + ++E LK + DF + +G Sbjct: 208 DA-HVTAVCSQDAS-ELVRKLGADDVIDYK--SGSVEEQLKSL--KPFDFILDNVGGSTE 261 Query: 276 MMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVAD 335 A + T V + P L+M+ + + G G +G K + Sbjct: 262 TWAPDFLKKWSGATYVTLVTP---FLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYR 318 Query: 336 F---------------MAKKFSLDALITHVLPFEKINEGFDLLHSGKS-IRTIL 373 + + + +I PF K+ E F + G + +T++ Sbjct: 319 WAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 372 >4DVJ-A nrPDB Length = 363 Score = 115 bits (289), Expect = 3e-26, Method: Composition-based stats. Identities = 61/311 (19%), Positives = 107/311 (34%), Gaps = 62/311 (19%) Query: 1 MSTAGKVIKCKAAVLWELKKPF----SIEEVEVAPPKA--HEVRIKMVAVGICGTDDHVV 54 + T + AV + P S+ ++E+ P H++ +++ AV + D V Sbjct: 13 LGTENLYFQSMKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVR 72 Query: 55 SGTMVTPLPV-ILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCL 113 T ++G++AAGIV +VG VT +PGD+V Sbjct: 73 RSTPPDGTDWKVIGYDAAGIVSAVGPDVTLFRPGDEV----------------------- 109 Query: 114 KNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLI 173 ++ GT+ +++ +VDE V + + + Sbjct: 110 ----FYAGSIIRPGTN------------------AEFHLVDERIVGRKPKTLDWAEAAAL 147 Query: 174 GCGFSTGYGSAVNVAKVT---PGSTCAVF---GLGGVGLSAIMGCKAAGAARIIAVDINK 227 T + + + V PG+ A+ G GGVG A+ + +IA Sbjct: 148 PLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTVIATASRP 207 Query: 228 DKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEAC 287 + K LGA I D+ KP+ + + G F F D A + Sbjct: 208 ETQEWVKSLGAHHVI---DHSKPLAAEVAALGLGAPAFVFSTT-HTDKHAAEIADLIAPQ 263 Query: 288 GTSVIVGVPPD 298 G ++ P Sbjct: 264 GRFCLIDDPSA 274 >5A3V-A nrPDB Length = 329 Score = 110 bits (275), Expect = 1e-24, Method: Composition-based stats. Identities = 66/359 (18%), Positives = 109/359 (30%), Gaps = 66/359 (18%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGT----MVTPLPVILGHEAAGIVESVGEGV 81 +V V PK++EV +K+ A + D + G + P I + AG V VG GV Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGV 84 Query: 82 TTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHF 141 K GDKV+ + Sbjct: 85 KNFKAGDKVVAVLS---------------------------------------------H 99 Query: 142 LGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP---GS--TC 196 LG +++ V E K + + T + N A + G Sbjct: 100 LGGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLDGTGKKANI 159 Query: 197 AVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 V GGVG A+ K A A + A K LGA E + DYK P L Sbjct: 160 LVTAASGGVGHYAVQLAKLANA-HVTAT-CGARNIEFVKSLGADEVL---DYKTPEGAAL 214 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTW 315 K + D + + G + + P++ + ++ + Sbjct: 215 KSPSGKKYDAVVHCANGIP--FSVFEPNLSENGKVIDITPGPNAMWTYAVKKITMSKKQL 272 Query: 316 KGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILM 374 +L E + +V K+ + +I P K + + G + I++ Sbjct: 273 VPLLL--IPKAENLEFMVNLV--KEGKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIV 327 >2WEK-A nrPDB Length = 341 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 51/273 (18%), Positives = 91/273 (33%), Gaps = 60/273 (21%) Query: 26 EVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT--PLPVILGHEAAGIVESVG-EGVT 82 + V P ++ ++ VG+ +D + +G P +G E G V ++G Sbjct: 24 DCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASA 83 Query: 83 TVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFL 142 G V ++ Sbjct: 84 RYTVGQAVA-------------------------------------------------YM 94 Query: 143 GISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GL 201 +F++YTVV + + + P + + +T Y S + ++ G V Sbjct: 95 APGSFAEYTVVPASIATPVPSVKP--EYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAA 152 Query: 202 GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 GG G A+ K A +I + +K A K LG IN + +P+ VLK+ Sbjct: 153 GGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLGCDRPINYK--TEPVGTVLKQEYPE 209 Query: 262 GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 GVD +E +G M + G +++G Sbjct: 210 GVDVVYESVGGA--MFDLAVDALATKGRLIVIG 240 >4EYE-A nrPDB Length = 342 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 69/374 (18%), Positives = 123/374 (32%), Gaps = 65/374 (17%) Query: 11 KAAVLWELKKP--FSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL--PVIL 66 KA L P +VE + V + + A G+C D + G + P + Sbjct: 23 KAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFVP 82 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 G E AG+V S EG + +KPGD+V+ Sbjct: 83 GIETAGVVRSAPEG-SGIKPGDRVMAFNF------------------------------- 110 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186 I +++ V + + + + + T Y + Sbjct: 111 -----------------IGGYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMYFAYAR 153 Query: 187 VAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 ++ G T V GG+G +AI K GA ++IAV K +GA + Sbjct: 154 RGQLRAGETVLVLGAAGGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADIVL--- 209 Query: 246 DYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSM 304 ++ + ++E T G GVD + IG + + G ++VG Sbjct: 210 PLEEGWAKAVREATGGAGVDMVVDPIGGP--AFDDAVRTLASEGRLLVVGFAAGGIPTIK 267 Query: 305 NPMLLLTGRTWKGAILGGF-KSKECVPKLVADFMAKKFS--LDALITHVLPFEKINEGFD 361 LLL + G G F ++ + K + + ++ +P + + Sbjct: 268 VNRLLLRNASLIGVAWGEFLRTHADYLYETQAGLEKLVAEGMRPPVSARIPLSEGRQALQ 327 Query: 362 LLHSGKS-IRTILM 374 GK + +L+ Sbjct: 328 DFADGKVYGKMVLV 341 >2CDC-A nrPDB Length = 366 Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats. Identities = 69/369 (18%), Positives = 135/369 (36%), Gaps = 36/369 (9%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKA-HEVRIKMVAVGICGTDDHVVSGTM-VTPLP----- 63 KA ++ +++V+ + +++I+ + GICG D +V+G + ++ LP Sbjct: 2 KAIIVKPPNAGVQVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKGKDF 61 Query: 64 VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGT 123 ++LGHEA G+VE G GD V+P+ CG CR C ++C + Sbjct: 62 LVLGHEAIGVVEESYHG---FSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIH 118 Query: 124 LQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 DG R P + + ++ +A I+ + T Sbjct: 119 KMDGFMREWWYDDPKYLVKIPKSIEDIGIL-AQPLADIEKSIEEILEVQKRVPVWTCDDG 177 Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAK-AKELGATECI 242 +N V G G +G+ + + G +A + + E T Sbjct: 178 TLNC------RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQTVIEETKTNYY 231 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 N + +++ + G D + G ++ +++ G + G S ++ Sbjct: 232 NSSNGYDKLKDSV-----GKFDVIIDATGADVNILGNVIPLLGRNGVLGLFG-FSTSGSV 285 Query: 303 SMN----PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDA---LITHVLPFEK 355 ++ ++ T +T G + G + +A + K A LIT + Sbjct: 286 PLDYKTLQEIVHTNKTIIGLVNGQKPHFQQAVVHLASW--KTLYPKAAKMLITKTVS--- 340 Query: 356 INEGFDLLH 364 IN+ +LL Sbjct: 341 INDEKELLK 349 >2VWH-A nrPDB Length = 357 Score = 98.6 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 74/384 (19%), Positives = 141/384 (36%), Gaps = 50/384 (13%) Query: 11 KAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLP-----VI 65 KA + + + E P++ E ++ + VG+ GTD V++G P ++ Sbjct: 2 KAIAVKRGEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHGG-FPEGEDHLV 60 Query: 66 LGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQ 125 LGHEA G+V T ++ GD V+P R + + Y ++ + Sbjct: 61 LGHEAVGVVVD--PNDTELEEGDIVVPTVR------RPPASGTNEYFERDQPDMAPDGM- 111 Query: 126 DGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASP-----LEKVCLIGCGFSTG 180 + R H S++ E + +I + +E + + Sbjct: 112 -----YFERGIVGAH----GYMSEFFTSPEKYLVRIPRSQAELGFLIEPISITEKALEHA 162 Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKA--AGAARIIAV---DINKDKFAKAKE 235 Y ++ + P S+ V G G +GL + K G + + D +E Sbjct: 163 Y-ASRSAFDWDP-SSAFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEE 220 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 L AT + Q + + +V ++M DF +E G + S+ G ++GV Sbjct: 221 LDATYVDSRQTPVEDVPDVYEQM-----DFIYEATGFPKHAIQSVQALAP-NGVGALLGV 274 Query: 296 PP----DSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVL 351 P + + + ++L + G++ + V K+ L+ L+T V Sbjct: 275 PSDWAFEVDAGAFHREMVLHNKALVGSV--NSHVEHFEAATVTFTKLPKWFLEDLVTGVH 332 Query: 352 PFEKINEGFDLLHSGKSIRTILMF 375 P + FD +I+T + F Sbjct: 333 PLSEFEAAFD--DDDTTIKTAIEF 354 >3WID-A nrPDB Length = 369 Score = 96.3 bits (238), Expect = 2e-20, Method: Composition-based stats. Identities = 69/369 (18%), Positives = 127/369 (34%), Gaps = 35/369 (9%) Query: 7 VIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLP--- 63 + A V K ++++ P+ +E ++K V +GICGTD V+G + Sbjct: 1 MSTINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEG 60 Query: 64 ---VILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120 ++LGHEA V V + +K GD V+PL + + GKC C+ + C D Sbjct: 61 ENFLVLGHEALLQVLDVSDN-NYIKRGDFVVPL-VRRPGKCVNCRIGRQDNCSIGDPDKH 118 Query: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKID-AASPLEKVCLIGCGFST 179 + + + V++ + KI PL+ V F Sbjct: 119 EAGITG--------LHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDV 170 Query: 180 GYGSAVNVAKVTP--GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 ++ + G V G G K G + V+ + + K K + Sbjct: 171 VSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRG-FDVTMVNRHDETENKMKMM- 228 Query: 238 ATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP 297 D+ LK+M D +D + G T+ + G ++ G Sbjct: 229 -------DDFGVGFSNYLKDMPDK-IDLLVDTSGDPSTIFK-FVKKVNNNGVVILFGFNG 279 Query: 298 DSQNLSMN----PMLLLTGRTWKGAILGG-FKSKECVPKLVADFMAKKFSLDALITHVLP 352 + +N ++ T G++ + + L + ++ +IT+ Sbjct: 280 KAPGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAK 339 Query: 353 FEKINEGFD 361 E+ N F Sbjct: 340 PEETNIFFQ 348 >5LB9-A nrPDB Length = 385 Score = 81.7 bits (200), Expect = 5e-16, Method: Composition-based stats. Identities = 49/299 (16%), Positives = 91/299 (30%), Gaps = 63/299 (21%) Query: 4 AGKVIKCKAAVLWELKKPFSI-----EEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTM 58 +I +A + + +P + E++ +EV +K + + +D + + G Sbjct: 19 GRHMITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVY 78 Query: 59 VTPL----------PVIL-GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNP 107 + P G+E V VG V++++ GD VIP + Sbjct: 79 PSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPSHV------------ 126 Query: 108 ESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPL 167 + + F P + Sbjct: 127 --------NFGTWRTHALGNDDDFIKLPNPAQSKANGK----------------PNGLTI 162 Query: 168 EKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF--GLGGVGLSAIMGCKAAGAARIIAVDI 225 + I Y + K+TPG + G VG A K I + Sbjct: 163 NQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIRD 222 Query: 226 NK---DKFAKAKELGATECI-----NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTM 276 + A KELGAT+ I N +++ I+E +K+ + G + +G + Sbjct: 223 RPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQ-SGGEAKLALNCVGGKSST 280 >1V3V-A nrPDB Length = 333 Score = 80.1 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 88/249 (35%), Gaps = 23/249 (9%) Query: 142 LGISTFSQYTVVD----ENAVAKIDAASPLEKV-CLIGCGFSTGYGSAVNVAKVTPGSTC 196 L S ++ + + D E + + PL IG T Y + V V G T Sbjct: 90 LAQSGWTTHFISDGKGLEKLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETV 149 Query: 197 AVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 V G VG K G +++ + +K A K++G N + ++E L Sbjct: 150 LVSAAAGAVGSVVGQIAKLKG-CKVVGAAGSDEKIAYLKQIGFDAAFNYKTV-NSLEEAL 207 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG----------VPPDSQNLSMN 305 K+ + G D F+ +G + ++L + G I G +PP S+ Sbjct: 208 KKASPDGYDCYFDNVGGE--FLNTVLSQMKDFGKIAICGAISVYNRMDQLPPGPSPESII 265 Query: 306 PMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS 365 L G + K + L+ + K +T FE + F + + Sbjct: 266 YKQLRIEGFIVYRWQGDVREK-ALRDLMKWVLEGKIQYHEHVTK--GFENMPAAFIEMLN 322 Query: 366 GKSIRTILM 374 G ++ ++ Sbjct: 323 GANLGKAVV 331 >5GXF-A nrPDB Length = 330 Score = 76.7 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 53/265 (20%), Positives = 88/265 (33%), Gaps = 62/265 (23%) Query: 9 KCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS--GTMVTPLPVIL 66 K +AAV K S+ ++ V EV + + + D + G +V P + Sbjct: 15 KTQAAV-----KQLSLTDLPV-----GEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVP 64 Query: 67 GHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQD 126 G + AG VE+ + KPGDKV+ + E++ Sbjct: 65 GIDFAGTVENSSDE--RYKPGDKVVLTGW---------RVGEAH---------------- 97 Query: 127 GTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS--A 184 +SQ V + + + + +G T + A Sbjct: 98 -----------------WGGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAMLAVMA 140 Query: 185 VNVAKVTPGS-TCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 + +TPG V G GGVG A G + AV + LGAT+ + Sbjct: 141 LEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLG-YEVAAVTGRPETADYLTSLGATQIV 199 Query: 243 NPQDYKKPIQEVL-KEMTDGGVDFS 266 + + ++ L E+ G VD Sbjct: 200 ARDEINETVKRPLESEIWAGCVDAV 224 >2Y05-A nrPDB Length = 328 Score = 72.8 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 39/231 (16%), Positives = 76/231 (32%), Gaps = 17/231 (7%) Query: 155 ENAVAKIDAASPLE-KVCLIGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVGLSAIMGC 212 E + + PL + +G T Y + + V G T V G VG Sbjct: 102 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 161 Query: 213 KAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 K G +++ + +K A ++LG N + + ++E LK+ + G D F+ +G Sbjct: 162 KLKG-CKVVGAVGSDEKVAYLQKLGFDVVFNYKTV-ESLEETLKKASPDGYDCYFDNVGG 219 Query: 273 LDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAIL---------GGF 323 +++ + G I G P + G Sbjct: 220 E--FSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGD 277 Query: 324 KSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILM 374 ++ + L+ + K I FE + F + G ++ ++ Sbjct: 278 ARQKALKDLLKWVLEGKIQYKEYIIE--GFENMPAAFMGMLKGDNLGKTIV 326 >1O89-A nrPDB Length = 345 Score = 70.5 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 53/323 (16%), Positives = 107/323 (33%), Gaps = 61/323 (18%) Query: 23 SIEEVEVAPPKAHEVRIKMVAVGICGTDDHVV--SGTMVTPLPVILGHEAAGIVESVGEG 80 S++ ++ + +V + + + D + G ++ P+I G + AG V + Sbjct: 37 SVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRT--SE 94 Query: 81 VTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHH 140 G +V+ T +H Sbjct: 95 DPRFHAGQEVL---------------------------------------LTGWGVGENH 115 Query: 141 FLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG--SAVNVAKVTP--GSTC 196 + ++ V + + + K +IG T A+ A V P G Sbjct: 116 W---GGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIV 172 Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 GGVG +A+ G +++AV + K LGA+ + P+D + + K Sbjct: 173 VTGASGGVGSTAVALLHKLG-YQVVAVSGRESTHEYLKSLGASRVL-PRDEFAESRPLEK 230 Query: 257 EMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPD-SQNLSMNPMLLLTGRT- 314 ++ G + + +G D ++A +L G G+ + ++ P +L R Sbjct: 231 QVWAG----AIDTVG--DKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQ 284 Query: 315 -WKGAILGGFKSKECVPKLVADF 336 + + + +LVAD Sbjct: 285 GVDSVMTPPERRAQAWQRLVADL 307 >2J3K-A nrPDB Length = 345 Score = 62.4 bits (150), Expect = 3e-10, Method: Composition-based stats. Identities = 50/264 (18%), Positives = 86/264 (32%), Gaps = 20/264 (7%) Query: 127 GTSRFTCRRKPIHHFL----GISTFSQYTVVDENAVAKI---DAASPLEK-VCLIGCGFS 178 G SR P + GI + +Y+V+ A PL L+G Sbjct: 82 GVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGM 141 Query: 179 TGYGSAVNVAKVTPGSTCAVFGL-GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK-EL 236 T Y V G T V G VG K G ++ +K+K K + Sbjct: 142 TAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCY-VVGSAGSKEKVDLLKTKF 200 Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 G + N ++ + LK G+D FE +G M+ ++L G + G+ Sbjct: 201 GFDDAFNYKEESD-LTAALKRCFPNGIDIYFENVGG--KMLDAVLVNMNMHGRIAVCGMI 257 Query: 297 PDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFM-----AKKFSLDALITHVL 351 + + L+ +K + GF + K ++ + + Sbjct: 258 SQYNLENQEGVHNLSNIIYKRNRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVAD 317 Query: 352 PFEKINEGF-DLLHSGKSIRTILM 374 EK E L H + +++ Sbjct: 318 GLEKAPEALVGLFHGKNVGKQVVV 341 >2VNA-A nrPDB Length = 357 Score = 58.2 bits (139), Expect = 6e-09, Method: Composition-based stats. Identities = 44/243 (18%), Positives = 84/243 (34%), Gaps = 26/243 (10%) Query: 151 TVVDENAVAKIDAASPLEKVC----LIGCGFSTGYGSAVNVAKVTPGS--TCAVFGL-GG 203 ++D N++ K+D + IG T +T GS T V G G Sbjct: 108 VILDGNSLEKVDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGA 167 Query: 204 VGLSAIMGCKAAGAARIIAV-DINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGG 262 G A G +R++ + ++ ELG IN + K + E L+E G Sbjct: 168 CGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYK--KDNVAEQLRESCPAG 225 Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVG-VPPDSQNLSMNPML------LLTGRTW 315 VD F+ +G + +++ ++ G + ++++ P L + R Sbjct: 226 VDVYFDNVGG--NISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNI 283 Query: 316 KGAILGGFKSKECVP----KLVADFMAKKFSLDALITHVLPFEKINEGFDLLHS-GKSIR 370 K+ +L F K + + + E + F + + G + Sbjct: 284 TRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKETVIN--GLENMGAAFQSMMTGGNIGK 341 Query: 371 TIL 373 I+ Sbjct: 342 QIV 344 >2ZB3-A nrPDB Length = 353 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 38/210 (18%), Positives = 69/210 (32%), Gaps = 21/210 (10%) Query: 172 LIGCGFSTGYGSAVNVAKVTPGS--TCAVFGL-GGVGLSAIMGCKAAGAARIIAV-DINK 227 IG T ++ GS T V G G G A G +R++ + + Sbjct: 134 AIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHLLGCSRVVGICGTQE 193 Query: 228 DKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEAC 287 ELG +N + + E L+E GGVD F+ +G + +++ Sbjct: 194 KCLFLTSELGFDAAVNYK--TGNVAEQLREACPGGVDVYFDNVGG--DISNAVISQMNEN 249 Query: 288 GTSVIVG---------VPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKEC--VPKLVADF 336 ++ G P ++ + T + + +K K + +L F Sbjct: 250 SHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVLNYKDKFEPGILQLSQWF 309 Query: 337 MAKKFSLDALITHVLPFEKINEGFDLLHSG 366 K + T E + F + +G Sbjct: 310 KEGKLKVKE--TMAKGLENMGVAFQSMMTG 337 >1ZCJ-A nrPDB Length = 463 Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVG-LSAIMGCKAAGAARIIAVDINKDKFAKAKEL 236 ST G++ A P S+ V GLG +G AI + ++AV+ + + AK++ Sbjct: 22 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 79 >3ZWA-A nrPDB Length = 742 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVG-LSAIMGCKAAGAARIIAVDINKDKFAKAKEL 236 ST G++ A P S+ V GLG +G AI + ++AV+ + + AK++ Sbjct: 301 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 358 >4DIO-A nrPDB Length = 405 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 34/143 (23%), Positives = 51/143 (35%), Gaps = 14/143 (9%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 + A P + V G G GL AI + GA + A D+ + LGA Sbjct: 177 ALPMMMTAAGTVPAAKIFVMGAGVAGLQAIATARRLGA-VVSATDVRPAAKEQVASLGAK 235 Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299 I +D +E T GG ++ E+ G A+L+ H A VI + Sbjct: 236 -FIAVED-----EEFKAAETAGG--YAKEMSGEYQVKQAALVAEHIAKQDIVI-----TT 282 Query: 300 QNLSMNPMLLLTGRTWKGAILGG 322 + P L R ++ G Sbjct: 283 ALIPGRPAPRLVTREMLDSMKPG 305 >5ILO-A nrPDB Length = 271 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 37/109 (33%), Gaps = 13/109 (11%) Query: 193 GSTCAVFG-LGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT----------EC 241 G V G GG+GL AAGAA++ +D+ + K A + Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDV 74 Query: 242 INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 N + + +E+ K T G +D V G + G Sbjct: 75 ANKKGVEATYEEIAK--TFGNIDIVVNVAGIFNDKDVQRTLLVNLGGII 121 >2EGU-A nrPDB Length = 308 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 181 YGSAVNVAKVTPGSTCA--VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGA 238 +A K+ PG T G G+GL+ + K A ++ ++ ++ + GA Sbjct: 53 IEAAEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGA 112 Query: 239 TECINP 244 + P Sbjct: 113 ELVLTP 118 >3MGG-A nrPDB Length = 276 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 41/108 (37%), Gaps = 9/108 (8%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKP 250 PG+ G G +G ++ K A I ++DI+ + KA+E I N + + Sbjct: 37 PGAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKARENTEKNGIKNVKFLQAN 95 Query: 251 IQEVLKEMTDGGVDFSFEV-----IGRLDTMMASLLCCHEACGTSVIV 293 I + D D F + + + SL + GT ++ Sbjct: 96 IFSL--PFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >1X14-A nrPDB Length = 401 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 30/136 (22%), Positives = 51/136 (37%), Gaps = 20/136 (14%) Query: 149 QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVA---------------KVTPG 193 TV+ ++V +I A L+ + + GY + V A KV P Sbjct: 116 NVTVMAMDSVPRISRAQSLDALSSM--ANIAGYRAIVEAAHEFGRFFTGQITAAGKVPPA 173 Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC-INPQDYKKPIQ 252 V G G GL+AI + GA + A D + + + +GA ++ ++ Sbjct: 174 K-VMVIGAGVAGLAAIGAANSLGAI-VRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGD 231 Query: 253 EVLKEMTDGGVDFSFE 268 K M+D + E Sbjct: 232 GYAKVMSDAFIKAEME 247 >2B25-A nrPDB Length = 336 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 43/118 (36%), Gaps = 16/118 (13%) Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGA-ARIIAVDINKDKFAKAKELGATECINP--- 244 + PG T G G G ++ KA G+ R+I+ ++ KD AK+ + Sbjct: 102 DINPGDTVLEAGSG-SGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKN-YKHWRDSWKL 159 Query: 245 ---QDYKKPIQEVLKEMTDGGVDF---SFEVIG----RLDTMMASLLCCHEACGTSVI 292 +++ + + K+++ D +F+ + + + G + Sbjct: 160 SHVEEWPDNVDFIHKDISGATEDIKSLTFDAVALDMLNPHVTLPVFYPHLKHGGVCAV 217 >2VHY-A nrPDB Length = 377 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 43/159 (27%), Gaps = 16/159 (10%) Query: 161 IDAASPLEKVCLIGCGFSTGYGSAVNVAK----------VTPGSTCAVFGLGGVGLSAIM 210 + +P+ +V Y V P V G G G +A Sbjct: 127 LPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPAD-VVVIGAGTAGYNAAR 185 Query: 211 GCKAAGAARIIAVDINKDKFAK--AKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFE 268 GA + +DIN DK + A+ G Y+ ++ G V Sbjct: 186 IANGMGA-TVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAV--LVP 242 Query: 269 VIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 + SL+ + V + + P Sbjct: 243 GAKAPKLVSNSLVAHMKPGAVLVDIAIDQGGCFEGSRPT 281 >1XLT-A nrPDB Length = 384 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 + + A P + VFG+G GL AI K GA ++A D+ + + LG Sbjct: 159 AFPMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLG 215 >3X2F-A nrPDB Length = 411 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 27/148 (18%), Positives = 45/148 (30%), Gaps = 14/148 (9%) Query: 174 GCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKA 233 G G ST N + G V G G G + GA R+I +++ K Sbjct: 178 GTGQSTWDAIMRNTNLLVAGKNVVVAGYGWCGRGIALRAAGLGA-RVIVTEVDPVK---- 232 Query: 234 KELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV 293 A E I P++E +K DF G D + + + Sbjct: 233 ----AVEAIMDGFTVMPMKEAVKI-----ADFVITASGNTDVLSKEDILSLKDGAVLANA 283 Query: 294 GVPPDSQNLSMNPMLLLTGRTWKGAILG 321 G + + + + + + G Sbjct: 284 GHFNVEIPVRVLEEIAVEKFEARPNVTG 311 >6BII-A nrPDB Length = 333 Score = 36.2 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 29/78 (37%), Gaps = 10/78 (12%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 + + + G T + G G +G + K G I K KELGA Sbjct: 137 AWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGMR--ILYTARSRKPEAEKELGAE 194 Query: 240 ECINPQDYKKPIQEVLKE 257 KP++E+L+E Sbjct: 195 F--------KPLEELLRE 204 >5JE5-A nrPDB Length = 247 Score = 36.2 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 49/139 (35%), Gaps = 25/139 (17%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G + GAA+++ VDI++ A+E + Y P++ Sbjct: 42 GKSVLDLACG-FGFFGREIYR-RGAAKVVGVDISEKMIELARE-------ESRKYGDPLE 92 Query: 253 EVLKEMTD----GGVDFS--------FEVIGRLDTMMASLLCCHEACGTSVIVGVPPD-- 298 ++++ + G D + + L M + + G V V PD Sbjct: 93 FHVRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAYTVDPDFS 152 Query: 299 --SQNLSMNPMLLLTGRTW 315 N + + +L R W Sbjct: 153 LAKGNFAKYGVNVLNERAW 171 >5EKU-A nrPDB Length = 390 Score = 35.8 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 VTP + G G GL ++M K GA ++AV+ +++ A+E Sbjct: 92 HVTPETGVLEIGAG-SGLLSLMAAK-LGAKWVVAVEGSEELAKLARE 136 >4M36-A nrPDB Length = 343 Score = 35.8 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 189 KVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 VTP + G G GL ++M K GA ++AV+ +++ A+E Sbjct: 57 HVTPETGVLEIGAG-SGLLSLMAAK-LGAKWVVAVEGSEELAKLARE 101 >6ACF-A nrPDB Length = 367 Score = 35.8 bits (81), Expect = 0.031, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAG--AARIIAVDINKDKFAKA-KELGATECINPQDYKK 249 G AV G VG A C+ A++I DINK+ A+A +E GA ++P D Sbjct: 173 GKVVAVQG---VGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAK-AVDPNDIYG 228 Query: 250 PIQEVLKEMTDGGV 263 ++ GG+ Sbjct: 229 VECDIFAPCALGGI 242 >1VH3-A nrPDB Length = 262 Score = 35.8 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 28/65 (43%), Gaps = 3/65 (4%) Query: 216 GAARIIAVDINKDKFAKAKELGATEC---INPQDYKKPIQEVLKEMTDGGVDFSFEVIGR 272 GA+R+I N++ AK GA C +N + + EV++++ + + G Sbjct: 41 GASRVIIATDNENVADVAKSFGAEVCMTSVNHNSGTERLAEVVEKLAIPDNEIIVNIQGD 100 Query: 273 LDTMM 277 + Sbjct: 101 EPLIP 105 >4XIJ-A nrPDB Length = 275 Score = 35.5 bits (80), Expect = 0.035, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDK----FAKAKELGA 238 V A T G + V G GG +A++ G RI V ++ K A+ GA Sbjct: 117 GVTGALGTAGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARRCGA 175 >5VMT-A nrPDB Length = 342 Score = 35.5 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 40/124 (32%), Gaps = 19/124 (15%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAV---------------DINKDKFAKAKELGAT 239 A+ G G +G A+ + A + AV D + +F EL Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDD 71 Query: 240 E-CINPQDYKKPIQEVLKEMTDG--GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 +N ++ K +E+ G GVD E G T A V++ P Sbjct: 72 AIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFF-TNKTKAEAHIRAGARKVVISAP 130 Query: 297 PDSQ 300 + Sbjct: 131 GGND 134 >5X7F-A nrPDB Length = 235 Score = 35.1 bits (79), Expect = 0.054, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 48/134 (35%), Gaps = 11/134 (8%) Query: 168 EKVCLIGCGFSTGYGSAVN--VAKVTPGSTCAVFG--LGGVGLSAIMGCKAAGAARIIAV 223 E+ IG G T A+ +AK++ G A G G GL + G + G I Sbjct: 52 ERATDIGAGAVTPAVGALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTI-- 109 Query: 224 DINKDKFAKAKELGATECINPQDYK---KPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL 280 DI + A++ A I P + QEVL + D D F +D Sbjct: 110 DIEPEHLRLARQAFAEAGIGPSRTRLISGRAQEVLTRLADASYDLVFIDADPIDQPDYVA 169 Query: 281 LCC--HEACGTSVI 292 + G V+ Sbjct: 170 EGVRLLRSGGVIVV 183 >1W1U-A nrPDB Length = 557 Score = 34.7 bits (78), Expect = 0.060, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 36/98 (36%), Gaps = 7/98 (7%) Query: 186 NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + G GLGG+G + + AGA + ++ + + E T ++ Q Sbjct: 160 HYGGSLKGKWVLTAGLGGMGGAQPLAATLAGACS-LNIESQQSRIDFRLE---TRYVDEQ 215 Query: 246 --DYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL 281 D + + K T G S + G ++ L+ Sbjct: 216 ATDLDDALVRIAK-YTAEGKAISIALHGNAAEILPELV 252 >4K2X-A nrPDB Length = 523 Score = 34.7 bits (78), Expect = 0.061, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 27/72 (37%), Gaps = 5/72 (6%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT----ECINPQDYKKPI 251 + G G GL + AGA R + ++ + +K LG E ++ + + Sbjct: 25 VVIAGAGPTGLMLACELRLAGA-RTLVLERLAEPVDFSKALGVHARTVELLDMRGLGEGF 83 Query: 252 QEVLKEMTDGGV 263 Q ++ G Sbjct: 84 QAEAPKLRGGNF 95 >1BW9-B nrPDB Length = 356 Score = 34.7 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T V GLG VG S AGA +++ D + ++ A A LG T Sbjct: 176 GLTVLVQGLGAVGGSLASLAAEAGA-QLLVADTDTERVAHAVALGHTAV 223 >1V8B-A nrPDB Length = 479 Score = 34.7 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 34/110 (30%), Gaps = 14/110 (12%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G VG K GA R+ +I+ +A G Sbjct: 257 GKIVVICGYGDVGKGCASSMKGLGA-RVYITEIDPICAIQAVMEGFNVV----------- 304 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 L E+ D G DF G +D + L + +G D + Sbjct: 305 -TLDEIVDKG-DFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQV 352 >5Z1Z-A nrPDB Length = 329 Score = 34.7 bits (78), Expect = 0.076, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T V G G +G++ + K G R++A D A A ELG Sbjct: 144 GKTAGVIGTGKIGVAMLRILKGFGM-RLLAFDPYPS--AAALELGVEYV 189 >1V9L-A nrPDB Length = 421 Score = 34.3 bits (77), Expect = 0.091, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 7/85 (8%) Query: 149 QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV-------NVAKVTPGSTCAVFGL 201 +Y+ + V + + P E ++TG+G AV + G T A+ G+ Sbjct: 159 EYSKIKGYNVPGVFTSKPPELWGNPVREYATGFGVAVATREMAKKLWGGIEGKTVAIQGM 218 Query: 202 GGVGLSAIMGCKAAGAARIIAVDIN 226 G VG + GA I DIN Sbjct: 219 GNVGRWTAYWLEKMGAKVIAVSDIN 243 >3D2L-A nrPDB Length = 243 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 23/52 (44%), Gaps = 4/52 (7%) Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 A + +V PG A G G G + ++ + VD++++ A+E Sbjct: 25 AWVLEQVEPGKRIADIGCGT-GTATLLLADHY---EVTGVDLSEEMLEIAQE 72 >3VPX-A nrPDB Length = 364 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKA-KELGATEC 241 G T AV G+G V + GA ++I DIN++ +A GAT Sbjct: 172 AGKTVAVQGVGNVAYALCEYLHEEGA-KLIITDINEEAVQRAVDAFGATAV 221 >4COO-A nrPDB Length = 563 Score = 33.9 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A + PG T G G+GL+ + ++ ++ +K + LGA Sbjct: 152 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 211 Query: 242 INPQDYK 248 P + + Sbjct: 212 RTPTNAR 218 >4CUK-A nrPDB Length = 338 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T V G G +G++A+ K G R++A D A +LG Sbjct: 144 GKTAGVIGTGKIGVAALRILKGFGM-RLLAFDPYPST--AALDLGVEYV 189 >1DXY-A nrPDB Length = 333 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 20/52 (38%), Gaps = 2/52 (3%) Query: 181 YGSAVNVAKVTPGS-TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFA 231 Y A G T V G G +G AI K GA ++IA D K Sbjct: 132 YEKAGTFIGKELGQQTVGVMGTGHIGQVAIKLFKGFGA-KVIAYDPYPMKGD 182 >1M54-A nrPDB Length = 363 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A + PG T G G+GL+ + ++ ++ +K + LGA Sbjct: 87 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 146 Query: 242 INPQDYK 248 P + + Sbjct: 147 RTPTNAR 153 >5MMS-A nrPDB Length = 408 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 2/67 (2%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A + PG T G G+GL+ + ++ ++ +K + LGA Sbjct: 130 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 189 Query: 242 INPQDYK 248 P + + Sbjct: 190 RTPTNAR 196 >5F8E-A nrPDB Length = 377 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 44/110 (40%), Gaps = 10/110 (9%) Query: 190 VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYK 248 + G+ A FG G G + + +A GA+R +D + + A E A + N + Sbjct: 185 LRSGADVADFGCG-SGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFER 243 Query: 249 KPIQEVLKEMTDGGVDF--SFEVI---GRLDTMMASLLCCHEACGTSVIV 293 + E+ K G D F+ I + ++ ++ G ++V Sbjct: 244 HDLAELDKV---GAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMV 290 >2YVG-A nrPDB Length = 408 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 45/138 (32%), Gaps = 17/138 (12%) Query: 162 DAASPLEKVCLIGCGFSTGYGSAVN-VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARI 220 A P + + A A + P S + G G +GL + AG + Sbjct: 113 PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGV-HV 171 Query: 221 IAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFE--VIGRLDTMMA 278 V+ ++A A + V + GVD FE V G +D ++ Sbjct: 172 SLVETQPRLMSRA----APATL--------ADFVARYHAAQGVDLRFERSVTGSVDGVVL 219 Query: 279 SLLCCHEACGTSVIVGVP 296 L V+VG+ Sbjct: 220 -LDDGTRIAADMVVVGIG 236 >4N7R-A nrPDB Length = 472 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 6/69 (8%) Query: 173 IGCGFSTGYGSAVNVAKVTPGST------CAVFGLGGVGLSAIMGCKAAGAARIIAVDIN 226 I G + +AV +A + + V G G +G I A G +++ V+ + Sbjct: 181 IASGAVSVSSAAVELALMKLPQSSNVSARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRS 240 Query: 227 KDKFAKAKE 235 +++ + +E Sbjct: 241 EERVSAIRE 249 >1EUF-A nrPDB Length = 227 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 41/96 (42%), Gaps = 9/96 (9%) Query: 111 YCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPL-EK 169 +CL + ++ G T + P+ + ++ T+ ++ + K+ + + +K Sbjct: 44 HCLGSSINVTLGAHNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDK 103 Query: 170 VCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVG 205 V I ++A+V PG C+V G G +G Sbjct: 104 VSPINLP--------RSLAEVKPGMMCSVAGWGRLG 131 >2ZJ1-A nrPDB Length = 495 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 31/102 (30%), Gaps = 14/102 (13%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G + G G VG K GA R+ +I+ +A G ++ Sbjct: 275 GKKVLICGYGDVGKGCAEAMKGQGA-RVSVTEIDPINALQAMMEGFDVV--------TVE 325 Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVG 294 E + G D G D +M + + +G Sbjct: 326 EAI-----GDADIVVTATGNKDIIMLEHIKAMKDHAILGNIG 362 >4AEC-A nrPDB Length = 430 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 31/85 (36%), Gaps = 8/85 (9%) Query: 184 AVNVAKVTPGSTCAV---FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 A ++PG + V G G+GL+ I + + ++ ++ K GA Sbjct: 165 AEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAEL 224 Query: 241 CIN-----PQDYKKPIQEVLKEMTD 260 + + +E+LK D Sbjct: 225 VLTDPAKGMTGAVQKAEEILKNTPD 249 >6GME-A nrPDB Length = 201 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 223 VDINKDKFAKAKELGATECINPQDYKKPIQEVLK 256 VD+ ++ A LGAT IN ++++ + V + Sbjct: 62 VDVREEGKENAFSLGATLWINSEEFEDLDEIVAR 95 >3EGI-A nrPDB Length = 206 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK 234 V GVG + I R+IA+DI+ K A A+ Sbjct: 46 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 82 >3GDH-A nrPDB Length = 241 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK 234 V GVG + I R+IA+DI+ K A A+ Sbjct: 81 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 117 >5JXW-A nrPDB Length = 498 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 36/111 (32%), Gaps = 14/111 (12%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G G VG G GA R+I +I+ +A G + + Sbjct: 270 AGKKIVVLGYGEVGKGCAQGLSGVGA-RVIVTEIDPICALQASMEGYQVSV--------L 320 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 302 ++V+ E D G D + + + +G D ++ Sbjct: 321 EDVVSE-----ADIFITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDV 366 >4OM8-A nrPDB Length = 309 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 42/120 (35%), Gaps = 13/120 (10%) Query: 195 TCAVFGLGGVG-LSAIMGCKAAGAARIIAVDINKDKFAKAKEL--GATECINPQDYKKPI 251 A+ GLG +G A + G +++A D+ +A+ + A ++ P Sbjct: 4 NIAIIGLGTMGPGMAARLAR--GGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPS 61 Query: 252 QEV--LKEMTD-----GGVDFSFEVIGRLDTMMASLLCCHEAC-GTSVIVGVPPDSQNLS 303 V ++ D G D E + ++ A + + G IV ++ Sbjct: 62 AGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPIT 121 >1JWB-B nrPDB Length = 249 Score = 32.8 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDIN 226 S + GLGG+G +A +AG + +D + Sbjct: 32 SRVLIVGLGGLGCAASQYLASAGVGNLTLLDFD 64 >2O23-A nrPDB Length = 265 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY--KKPIQE 253 G G+GL+ GA+ ++ N A+AK+LG P D +K +Q Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 254 VLKEMTD--GGVDFSFEVIGRLDTMMA 278 L G VD + G Sbjct: 76 ALALAKGKFGRVDVAVNCAGIAVASKT 102 >2EKL-A nrPDB Length = 313 Score = 32.8 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T + G G +G + A G +++A DI + KA+++ A Sbjct: 141 AGKTIGIVGFGRIGTKVGIIANAMGM-KVLAYDILDIR-EKAEKINAKAV 188 >1E3W-A nrPDB Length = 261 Score = 32.8 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 6/88 (6%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 G G+GLS GA ++ N + +AK+LG P + +EV Sbjct: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE-KEVQ 72 Query: 256 KEMTD-----GGVDFSFEVIGRLDTMMA 278 +T G +D + G + Sbjct: 73 AALTLAKEKFGRIDVAVNCAGIAVAIKT 100 >6C55-A nrPDB Length = 340 Score = 32.8 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 28/81 (34%), Gaps = 9/81 (11%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKEL 236 +T Y G AV G G G + K G +I + + F KAKE Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRS-FDKAKED 59 Query: 237 GATECINPQDYKKPIQEVLKE 257 G P+ E +K+ Sbjct: 60 GFDVF--------PVAEAVKQ 72 >6IQV-A nrPDB Length = 340 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 N + Y +P + + + + GVDF E G T A +A V++ P S Sbjct: 75 NYRVYAEPQAQNIPWVKNDGVDFVLECTG-FYTSKAKSQAHLDAGAKRVLISAPAGSD 131 >2ISQ-A nrPDB Length = 320 Score = 32.4 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 31/99 (31%), Gaps = 8/99 (8%) Query: 184 AVNVAKVTPGSTCAV---FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240 A + PG + + G GVGL+ K + ++ ++ G Sbjct: 55 AEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVEL 114 Query: 241 CIN-----PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLD 274 + + +E+L + +G + FE Sbjct: 115 VLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPK 153 >5AOV-A nrPDB Length = 336 Score = 32.4 bits (72), Expect = 0.36, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 25/65 (38%), Gaps = 10/65 (15%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G T + G G +G + K I K KELGA +P++ Sbjct: 150 GKTIGIVGFGRIGQAIARRAKGFNMR--ILYYSRTRKSQAEKELGAEY--------RPLE 199 Query: 253 EVLKE 257 EVLKE Sbjct: 200 EVLKE 204 >3KYD-B nrPDB Length = 551 Score = 32.4 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 19/45 (42%) Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDIN 226 G +A+ G V G GG+G + G + I +D++ Sbjct: 8 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 52 >3KYC-B nrPDB Length = 660 Score = 32.4 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 19/45 (42%) Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDIN 226 G +A+ G V G GG+G + G + I +D++ Sbjct: 26 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 70 >2EEZ-A nrPDB Length = 369 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 36/113 (31%), Gaps = 1/113 (0%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + + G G VG +A GA ++ +D+N + ++ I + I++ Sbjct: 168 SVVILGGGTVGTNAAKIALGMGA-QVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKS 226 Query: 255 LKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPM 307 ++ + +L + V V V ++ P Sbjct: 227 VQHADLLIGAVLVPGAKAPKLVTRDMLSLMKEGAVIVDVAVDQGGCVETIRPT 279 >5MH6-A nrPDB Length = 308 Score = 32.0 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 24/147 (16%), Positives = 42/147 (28%), Gaps = 16/147 (10%) Query: 74 VESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTC 133 VE GE PGD V G + + +C++ + + + Sbjct: 32 VEFAGED-EQFGPGDAVASF-----GHRDAFLDADWVHCIRAGYDEFPVGVYEEAGTYLT 85 Query: 134 RRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG 193 IH T + Y + + + + + Y +A G Sbjct: 86 NSTGIHGTTVGETVAGYMLTFARRLHAY-RDAQHDHAWDLP-----RYEEPFTLA----G 135 Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARI 220 V GLG +G + A G + Sbjct: 136 ERVCVVGLGTLGRGVVDRAAALGMEVV 162 >6BQ5-A nrPDB Length = 331 Score = 32.0 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 24/62 (38%), Gaps = 4/62 (6%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + G GG G +A + +++ DI+++ K +N + + E Sbjct: 103 KNVFIMG-GGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSY---LVVNKEAFHDSRLE 158 Query: 254 VL 255 V+ Sbjct: 159 VV 160 >1CYD-A nrPDB Length = 244 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 193 GSTCAVFGLG-GVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 G V G G G+G + A+GA + N D + AKE Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKE 50 >3D3W-A nrPDB Length = 244 Score = 32.0 bits (71), Expect = 0.44, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 192 PGSTCAVFGLG-GVGLSAIMGCKAAGAARIIAVDINKDKFA 231 G V G G G+G + A GA R++AV + Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGA-RVVAVSRTQADLD 45 >6FZI-A nrPDB Length = 332 Score = 32.0 bits (71), Expect = 0.46, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 39/129 (30%), Gaps = 22/129 (17%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAV-DINKDK----------------FAKAKELG 237 A+ G G +G A+ ++A+ D+ K + G Sbjct: 3 KVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVKEG 62 Query: 238 ATECINPQDYKKPIQEVLKEMTDG--GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 A +N ++ K + E+ G GVD E G + + VI Sbjct: 63 A-FVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAGAKKVVI--S 119 Query: 296 PPDSQNLSM 304 P +L Sbjct: 120 APAGNDLPT 128 >1XDW-A nrPDB Length = 331 Score = 32.0 bits (71), Expect = 0.47, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 24/65 (36%), Gaps = 3/65 (4%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDK--FAKAKELGATECINPQDYKKPIQ 252 T V GLG +G A GA +I D+ + K ++ E + D Sbjct: 148 TVGVVGLGRIGRVAAQIFHGMGA-TVIGEDVFEIKGIEDYCTQVSLDEVLEKSDIITIHA 206 Query: 253 EVLKE 257 +KE Sbjct: 207 PYIKE 211 >3G1U-A nrPDB Length = 437 Score = 32.0 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINK 227 G TC V G G VG +A GA R++ +++ Sbjct: 211 AGKTCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDP 245 >4FS8-A nrPDB Length = 383 Score = 32.0 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 29/177 (16%), Positives = 60/177 (33%), Gaps = 21/177 (11%) Query: 104 CKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDA 163 C + C K+ +++D + + + L S V E+ + Sbjct: 5 CASG----CQKSKNGGSTPSIRDHVADYYGKTLQSSADLKTSACKLAAAVPESHRKILAD 60 Query: 164 ASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGA-ARIIA 222 + GCG + ++ G+T G G G + K G ++I Sbjct: 61 IADEVLEKFYGCGSTLPADGSLE------GATVLDLGCGT-GRDVYLASKLVGEHGKVIG 113 Query: 223 VDINKDKFAKAKE---------LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVI 270 VD+ ++ A++ G+ N + K I+ + +G D S +++ Sbjct: 114 VDMLDNQLEVARKYVEYHAEKFFGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIV 170 >5UYY-A nrPDB Length = 381 Score = 32.0 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 25/63 (39%), Gaps = 5/63 (7%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECIN--PQDYKKPI 251 + G G +G S + K I DI +++ +AKEL ++ D + Sbjct: 18 KKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKEL---HVVDEIAVDLQHAC 74 Query: 252 QEV 254 +E Sbjct: 75 EEA 77 >1I9G-A nrPDB Length = 280 Score = 31.6 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 44/116 (37%), Gaps = 7/116 (6%) Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAG-AARIIAVDINKDKFAKAKEL--GATEC 241 V+ + PG+ G G G + +A G A ++I+ + D A+ G Sbjct: 92 VHEGDIFPGARVLEAGAG-SGALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGC-YG 149 Query: 242 INPQDYKKPIQEVL-KEMTDGGVD-FSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295 P +++ + ++ E+ DG VD +++ + + A V V Sbjct: 150 QPPDNWRLVVSDLADSELPDGSVDRAVLDMLAPWEVLDAVSRLLVAGGVLMVYVAT 205 >5D84-A nrPDB Length = 326 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 19/60 (31%), Gaps = 2/60 (3%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVD--INKDKFAKAKELGA 238 + +T + G +G++ M K G VD I+ K GA Sbjct: 55 IEHGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGA 114 >1ZFN-A nrPDB Length = 253 Score = 31.6 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFA 231 S + GLGG+G A + AG ++ D + + Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLS 68 >4DIB-A nrPDB Length = 345 Score = 31.6 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 46/134 (34%), Gaps = 31/134 (23%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAV---------------DINKDKFAKAKELGAT 239 A+ G G +G A I+A+ D KF E Sbjct: 6 RVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAFED 65 Query: 240 ECI---------NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTS 290 + N +D K+ TD GV+ E G+ ++ ++L EA Sbjct: 66 HLLVDGKMIRLLNNRDPKE------LPWTDLGVEVVIEATGKFNSKEKAIL-HVEAGAKK 118 Query: 291 VIVGVPPDSQNLSM 304 VI+ P ++++++ Sbjct: 119 VILTAPGKNEDVTI 132 >5M0P-A nrPDB Length = 428 Score = 31.6 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 16/124 (12%), Positives = 42/124 (33%), Gaps = 15/124 (12%) Query: 237 GATECINPQDYKKPIQEVLKEMTDGGVDFS--------------FEVIGRLDTMMASLLC 282 GA ++ + + + MT+G +++ E + ++ S++ Sbjct: 88 GAIHTVDGKKHVDRKALFMSLMTEGNLNYVRELTRTLWHANTQRMESMDEVNIYRESIVL 147 Query: 283 CHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWK-GAILGGFKSKECVPKLVADFMAKKF 341 + V PP+ M ++ G G+K+ + + V D++ ++ Sbjct: 148 LTKVGTRWAGVQAPPEDIERIATDMDIMIDSFRALGGAFKGYKASKEARRRVEDWLEEQI 207 Query: 342 SLDA 345 Sbjct: 208 IETR 211 >3OAM-A nrPDB Length = 252 Score = 31.2 bits (69), Expect = 0.69, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 39/107 (36%), Gaps = 5/107 (4%) Query: 179 TGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKA-KELG 237 T A + PG A G + AGA R+I + + ++ +A + G Sbjct: 4 TVVIPARYQSTRLPGKPLADIGGKPMIQWVYEQAMQAGADRVI-IATDDERVEQAVQAFG 62 Query: 238 ATECI---NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLL 281 C+ N Q + + EV+ +M V G + +++ Sbjct: 63 GVVCMTSPNHQSGTERLAEVVAKMAIPADHIVVNVQGDEPLIPPAII 109 >4XGI-A nrPDB Length = 436 Score = 31.2 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 19/48 (39%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVD 224 F G +A G+ AV G G VG A + AGA I D Sbjct: 215 FVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQD 262 >5U9P-A nrPDB Length = 265 Score = 31.2 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 34/90 (37%), Gaps = 14/90 (15%) Query: 193 GSTCAVFGLG-GVGLSAIMGCKAAGAARIIAVDINKDKFA-KAKE-----LGATECI--- 242 G + G G G+GL+ G AGAA +I D N++K A A+ A + Sbjct: 20 GRRALITGSGRGIGLTLARGLAEAGAAIVIN-DRNEEKAATLARRFRDEGFAADHAVFDV 78 Query: 243 -NPQDYKKPIQEVLKEMTDGGVDFSFEVIG 271 + I E + G +D G Sbjct: 79 AEHAQVRAAIDEFEARV--GAIDILVNNAG 106 >5JJC-A nrPDB Length = 342 Score = 31.2 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 24/62 (38%), Gaps = 6/62 (9%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAIMGCKAAGAARIIAV--DINKDKFAKAKELGAT 239 A + PG G G+GL+ M KA G I + +++K + LGA Sbjct: 53 AEKRGLLRPGGVIVEGTAGNTGIGLT--MVAKALGYRTAIVIPETASQEKKDALRLLGAE 110 Query: 240 EC 241 Sbjct: 111 LI 112 >3AOE-A nrPDB Length = 424 Score = 31.2 bits (69), Expect = 0.81, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 1/47 (2%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAV 223 F T +A + G+ A+ G G VG +A AR++AV Sbjct: 203 FITAAAAAEKIGLQVEGARVAIQGFGNVGNAAAR-AFHDHGARVVAV 248 >1GPJ-A nrPDB Length = 404 Score = 30.8 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 26/65 (40%), Gaps = 5/65 (7%) Query: 182 GSAVNVAKVTPGS----TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDK-FAKAKEL 236 +AV +A+ GS T V G G +G + G ++ + ++ A++L Sbjct: 152 SAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDL 211 Query: 237 GATEC 241 G Sbjct: 212 GGEAV 216 >1W7I-A nrPDB Length = 795 Score = 30.8 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 39/111 (35%), Gaps = 1/111 (0%) Query: 73 IVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFT 132 V E + KPGDKV+ L + + C +P++ + D T+ Sbjct: 20 EVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDPKTKELPPLRNPDILVGENDLTALSY 79 Query: 133 CRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGS 183 + H L + F ++ + A +P E++ + G Y Sbjct: 80 LHEPAVLHNLKV-RFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129 >2HMT-A nrPDB Length = 144 Score = 30.8 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKK 249 AV GLG G S + G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE 62 >4WJI-A nrPDB Length = 293 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 42/132 (31%), Gaps = 13/132 (9%) Query: 194 STCAVFGLGGVGLSAIMGCK-AAGAARIIAVDINKDKFAKAKE--LGATECINPQDYKKP 250 T A+ G+G +G S + A I+ ++ +A E LG ++ + + Sbjct: 5 QTIALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELGLGDRYTLSAAEAVEG 64 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 310 V+ + +G + A + + VG S M P L Sbjct: 65 ADLVVVSVP----------VGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPK 114 Query: 311 TGRTWKGAILGG 322 G + G Sbjct: 115 DVHFVPGHPIAG 126 >4PZE-A nrPDB Length = 284 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 15/38 (39%), Gaps = 1/38 (2%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAK 232 T + G G +G C G ++ VDI+ K Sbjct: 5 TVGIVGAGTMGNGIAQACAVVG-LNVVMVDISDAAVQK 41 >5BUT-A nrPDB Length = 288 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKK 249 AV GLG G S + G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE 62 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKK 249 AV GLG G S + G ++AVDIN++K I N + + Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE 204 >5FUB-A nrPDB Length = 337 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 16/44 (36%) Query: 199 FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 242 G G + L + K AG + A + + K+ G + Sbjct: 53 CGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVV 96 >4MOP-A nrPDB Length = 633 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 196 CAVFGLGGVGLSAIMGCK-AAGAA-RIIAVDINKDKFAKAKELGATECINPQDYKKPIQE 253 + G G +G + + GA ++ DI + ++GA + N +Y+K I + Sbjct: 49 VVIVGSGPIGCT---YARELVGAGYKVAMFDIGE--IDSGLKIGAHKK-NTVEYQKNIDK 102 Query: 254 VLKEMTD 260 + + Sbjct: 103 FVNVIQG 109 >4K28-A nrPDB Length = 269 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 18/49 (36%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDK 229 G+A G V G GGVG + AG A I D + + Sbjct: 113 LGAAHKHGFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTAR 161 >5UJU-A nrPDB Length = 576 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 25/99 (25%), Gaps = 4/99 (4%) Query: 220 IIAVDINKDKFAKAKELGATE----CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDT 275 +IA D A E+ A I + GGV S + G + Sbjct: 463 VIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFV 522 Query: 276 MMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRT 314 ++ G + N ++ R Sbjct: 523 NQSAAFSDFHGTGANPAANAALADAAFVANRFRVVQSRV 561 >6DLL-A nrPDB Length = 398 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 10/27 (37%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIA 222 A+ G G GL AG II Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIV 34 >1QO8-A nrPDB Length = 566 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 188 AKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINK 227 A + + V G G G +A + K AGA +I VD Sbjct: 116 AGPSETTQVLVVGAGSAGFNASLAAKKAGA-NVILVDKAP 154 >6J0Z-C nrPDB Length = 491 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 S V G G GL + AG + ++ +D + +++ LG Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVS-VVVLDKLAEPIKESRALG 48 >3F9I-A nrPDB Length = 249 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 20/46 (43%), Gaps = 5/46 (10%) Query: 193 GSTCAVFGLG-GVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 G T + G G+G + G +++I N++K K LG Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLG-SKVIISGSNEEKL---KSLG 55 >5NMX-A nrPDB Length = 425 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/22 (45%), Positives = 11/22 (50%) Query: 195 TCAVFGLGGVGLSAIMGCKAAG 216 AV G G GL+A K AG Sbjct: 3 RVAVLGAGPSGLTAARYLKQAG 24 >3BKX-A nrPDB Length = 275 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 21/49 (42%), Gaps = 1/49 (2%) Query: 178 STGYGSAV-NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDI 225 T + A+ +V PG G G LSA++ + + + +DI Sbjct: 28 QTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDI 76 >4YRY-B nrPDB Length = 468 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 17/46 (36%) Query: 190 VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 + G AV G G + A GA ++ V ++ A+ Sbjct: 276 IRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARR 321 >3EMK-A nrPDB Length = 246 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 31/89 (34%), Gaps = 15/89 (16%) Query: 193 GSTCAVFGL-GGVGLSAIMGCKAAGAARIIAV--DINKDKF-AKAKELGATECINPQDYK 248 G V G GG+G +A A I ++K A ELG + P + Sbjct: 7 GRKALVTGATGGLGE---AIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLS 63 Query: 249 KPIQEVLKEMTD------GGVDFSFEVIG 271 +E +K + GGVD G Sbjct: 64 D--REAVKALGQKAEEEMGGVDILVNNAG 90 >4RS3-A nrPDB Length = 327 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 30/86 (34%), Gaps = 21/86 (24%) Query: 204 VGLSAIMGCKAAG--AARIIAVDINKDKFAKAKE---LG----------------ATECI 242 +GL A+ K AG I+ +D +D K +G A + Sbjct: 205 MGLGALQALKEAGRTGVPIVGIDGIEDGLNAVKSGDFIGTSLQNGTVELSAGLAVADALV 264 Query: 243 NPQDYKKPIQEVLKEMTDGGVDFSFE 268 +D K V+ +T VD + E Sbjct: 265 KGEDVKTDPVYVMPAITKDNVDVAIE 290 >2WMH-A nrPDB Length = 581 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/122 (12%), Positives = 39/122 (31%), Gaps = 5/122 (4%) Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIG-----RLDTMMASLLCCHEACGTSVIVGVPPD 298 + E++ T GG ++FE A ++ P Sbjct: 269 SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAPSK 328 Query: 299 SQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINE 358 + ++ + G ++ G ++ + + + ++ + +I + EKI+ Sbjct: 329 EEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKEKISS 388 Query: 359 GF 360 F Sbjct: 389 IF 390 >1NVM-B nrPDB Length = 312 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 34/98 (34%), Gaps = 10/98 (10%) Query: 195 TCAVFGLGGVG--LS--AIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 A+ G G +G L + K ++ +D D A+A+ +G T Sbjct: 6 KVAIIGSGNIGTDLMIKVLRNAKYLEMGAMVGIDAASDGLARAQRMGVTTTY------AG 59 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACG 288 ++ ++K +DF F+ + L G Sbjct: 60 VEGLIKLPEFADIDFVFDATSASAHVQNEALLRQAKPG 97 >5OHX-A nrPDB Length = 504 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 25/65 (38%), Gaps = 2/65 (3%) Query: 184 AVNVAKVTPGSTCA--VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 A + + PG T G G+GL+ + ++ ++ +K + LGA Sbjct: 89 AEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKII 148 Query: 242 INPQD 246 P + Sbjct: 149 RTPTE 153 >3NJ4-A nrPDB Length = 435 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 18/45 (40%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINK-DKFAKAKE 235 G V G G VG + GA R+I +I+ + A E Sbjct: 215 AGKVAVVAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAME 258 >2AS0-A nrPDB Length = 396 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 19/47 (40%), Gaps = 4/47 (8%) Query: 190 VTPGSTCA-VFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 V PG VF G AI AGA +I +D + AKE Sbjct: 215 VQPGDRVLDVFTY--TGGFAIHAA-IAGADEVIGIDKSPRAIETAKE 258 >6GBN-A nrPDB Length = 438 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 28/94 (29%), Gaps = 14/94 (14%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G V G G VG + + AGA R+I +I+ +A A + + + Sbjct: 218 AGKVAVVAGYGDVGKGSAASLRGAGA-RVIVTEIDPICALQA----AMDGYEVKKMADAV 272 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHE 285 + D G + + Sbjct: 273 KR---------ADIVVTATGNKNIITGEHFKAMR 297 >3HM2-A nrPDB Length = 178 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 36/119 (30%), Gaps = 6/119 (5%) Query: 202 GGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 GG G AI ++ + +I++++ + ++ + + + Sbjct: 34 GGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVSDRIAVQQGAPRAFDDVPD 93 Query: 262 GVDFSFEVIG-RLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAI 319 D F G + A+ G V V + ML + + G I Sbjct: 94 NPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAV-----TVESEQMLWALRKQFGGTI 147 >1VE9-A nrPDB Length = 347 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 14/44 (31%) Query: 253 EVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 E +E+ GG D G ++ G + V P Sbjct: 165 ESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAP 208 >3FBT-A nrPDB Length = 282 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 3/84 (3%) Query: 180 GYGSAVNVAKVT-PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGA 238 G+G ++ +V + C V G GG + + K A I V N +K ++ G Sbjct: 108 GFGKMLSKFRVEIKNNICVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEK--TSEIYGE 165 Query: 239 TECINPQDYKKPIQEVLKEMTDGG 262 + I+ + +V+ T G Sbjct: 166 FKVISYDELSNLKGDVIINCTPKG 189 >2EFY-A nrPDB Length = 304 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 26/69 (37%), Gaps = 4/69 (5%) Query: 184 AVNVAKVTPGSTCAVF----GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 A + PGS + G G+GL+ I + + +++++ K GA Sbjct: 51 AEERGILRPGSGQVIVEPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAE 110 Query: 240 ECINPQDYK 248 + + + Sbjct: 111 LVLTDPERR 119 >1DOD-A nrPDB Length = 394 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 10/26 (38%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARII 221 A+ G G GL AG +I Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVI 30 >2BRY-A nrPDB Length = 497 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%) Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIA 222 + + C V G G GL A + GA ++ Sbjct: 82 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 121 >4TXK-A nrPDB Length = 615 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%) Query: 183 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIA 222 + + C V G G GL A + GA ++ Sbjct: 74 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 113 >4J90-A nrPDB Length = 222 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 22/57 (38%), Gaps = 2/57 (3%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKK 249 AV GLG G S G ++AVDIN++K I N + + Sbjct: 7 KQFAVIGLGRFGGSICKELHRMG-HEVLAVDINEEKVNAYASYATHAVIANATEENE 62 >1LTH-T nrPDB Length = 319 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 190 VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAV-DINKDKFAK 232 V P AV G G VG + G AR I + DI K++ Sbjct: 5 VKPTK-LAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >3X43-A nrPDB Length = 332 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 21/60 (35%), Gaps = 2/60 (3%) Query: 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVD--INKDKFAKAKELGATECINP 244 + PG T G VG++ M A G + + + ++ + G + P Sbjct: 57 KGLLKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFP 116 >4XWI-A nrPDB Length = 262 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 28/78 (35%), Gaps = 3/78 (3%) Query: 212 CKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK---KPIQEVLKEMTDGGVDFSFE 268 + + A+R++ ++ A + GA + ++ ++EV + Sbjct: 47 ARKSAASRVVVATDDERILAACQGFGAEALLTRAEHNSGTDRLEEVASRLGLASDAIVVN 106 Query: 269 VIGRLDTMMASLLCCHEA 286 V G + +L+ A Sbjct: 107 VQGDEPLIPPALIDQVAA 124 >5TQV-A nrPDB Length = 233 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 194 STCAVFGLG-GVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT-ECINPQDYKKPI 251 T + G G+G + + G +IA + A + LGA ++ + I Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGW-NVIATARDDASLAALRALGAHAHALDITQP-EQI 67 Query: 252 QEVLKEMTDGGVDFSFEVIGR 272 + ++ +D + V G Sbjct: 68 AALGWKLDGERLDVAVVVSGV 88 >3DC2-A nrPDB Length = 529 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 12/28 (42%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARI 220 G T V GLG +G A GA + Sbjct: 142 GKTVGVVGLGRIGQLVAQRIAAFGAYVV 169 >2WWR-A nrPDB Length = 330 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 20/52 (38%), Gaps = 1/52 (1%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 ST + GLG +G + K G R + + +A E A P+ Sbjct: 156 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP-RPEEAAEFQAEFVSTPE 206 >3ZZN-A nrPDB Length = 310 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 25/81 (30%), Gaps = 4/81 (4%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254 + G G VG + G AR + + K A+A A + ++ + P+ Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAH---AEDILHATPFAHPVWVW 58 Query: 255 LKEMTD-GGVDFSFEVIGRLD 274 D G G Sbjct: 59 AGSYGDLEGARAVVLAAGVAQ 79 >3WGE-A nrPDB Length = 113 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 22/76 (28%), Gaps = 2/76 (2%) Query: 83 TVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSN--PQGTLQDGTSRFTCRRKPIHH 140 V GD I P CG C+ L + S G + C + Sbjct: 17 HVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRG 76 Query: 141 FLGISTFSQYTVVDEN 156 + + F VD+ Sbjct: 77 YPTLLWFRDGKKVDQY 92 >6HNS-A nrPDB Length = 454 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 12/27 (44%), Gaps = 3/27 (11%) Query: 195 TCAVFGLGGVGLS---AIMGCKAAGAA 218 A+ G G GL+ A A GAA Sbjct: 4 RVAIIGAGPCGLAQLRAFQSAAAKGAA 30 >3GDF-A nrPDB Length = 267 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 46/128 (35%), Gaps = 14/128 (10%) Query: 178 STGYGSAVNVAKVTPGSTCAVFGLG---GVGLSAIMGCKAAGAARIIAVDINKD-KFAKA 233 +T + S ++ + G V G G+G+ A GC GAA I Sbjct: 6 ATKHESLLDQLSLK-GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENV 64 Query: 234 KELGATECINPQDYK------KPIQEVLKEMTD--GGVDFSFEVIGRLDTMMASLLCCHE 285 KEL T I + YK + ++++K++ G +D G L E Sbjct: 65 KELEKTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATAD-SGILDGSVE 123 Query: 286 ACGTSVIV 293 A V V Sbjct: 124 AWNHVVQV 131 >1ZVF-A nrPDB Length = 176 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 23/60 (38%) Query: 281 LCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKK 340 C H+ T +IVG P + + +NP + +L + PK + + + Sbjct: 28 YCLHKGGFTVMIVGGPNERTDYHINPTPEWFYQKKGSMLLKVVDETDAEPKFIDIIINEG 87 >1FI8-A nrPDB Length = 228 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 14/98 (14%), Positives = 30/98 (30%), Gaps = 7/98 (7%) Query: 111 YCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKV 170 +C + + G + P+ + ++ T+ ++ + K+ + + Sbjct: 45 HCSGSKIQVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSA 104 Query: 171 CLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSA 208 KV PG C V G G +G Sbjct: 105 VK-------PLNLPRRNVKVKPGDVCYVAGWGKLGPMG 135 >5ZBK-A nrPDB Length = 203 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 21/58 (36%), Gaps = 7/58 (12%) Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCA------VFGLGGVGLS-AIMGCKAAGAARIIAV 223 + CG S G A V G A V+G G VGL + A +I + Sbjct: 8 VFCGASPGASPVYQEAAVALGRHLAERGLTLVYGGGAVGLMGTVADAALAAGGEVIGI 65 >5XJ2-A nrPDB Length = 454 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 11/84 (13%), Positives = 29/84 (34%), Gaps = 4/84 (4%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKA-KELGAT 239 Y +A++ A++ + G+G + K + V++ + + K Sbjct: 293 YQTAIDFAELKK-DDVIIDAYSGIGTIGLSVAKHV--KEVYGVELIPEAVENSQKNASLN 349 Query: 240 ECINPQDYKKPIQEVLKEMTDGGV 263 + N + +K+ G+ Sbjct: 350 KITNAHYVCDTAENAMKKWLKEGI 373 >4LMA-A nrPDB Length = 326 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 25/65 (38%), Gaps = 3/65 (4%) Query: 183 SAVNVAKVTPGSTCAV---FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGAT 239 SA + P +T V G G+ L+ K + ++ ++ A K GAT Sbjct: 63 SAEKAGLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGAT 122 Query: 240 ECINP 244 + P Sbjct: 123 LELTP 127 >2E28-A nrPDB Length = 587 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 50/153 (32%), Gaps = 13/153 (8%) Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 +AV V G + VG + G+ ++ V + D AK + Sbjct: 432 MLDVAVDAAVRSGLVKHGDLVVITAGVPVGET--------GSTNLMKVHVISDLLAKGQG 483 Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEV-IGRLDTMMASLLCCHEACG---TSV 291 +G K +E ++M DGG+ + + + + E G + Sbjct: 484 IGRKSAFGKAVVAKTAEEARQKMVDGGILVTVSTDADMMPAIEKAAAIITEEGGLTSHAA 543 Query: 292 IVGVPPD-SQNLSMNPMLLLTGRTWKGAILGGF 323 +VG+ + + L + + GGF Sbjct: 544 VVGLSLGIPVIVGVENATTLFKDGQEITVDGGF 576 >1WG8-A nrPDB Length = 285 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 3/60 (5%) Query: 177 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKEL 236 Y A+++ V PG LGG G + + + R+I +D + + A+AK L Sbjct: 7 VPVLYQEALDLLAVRPGGVYVDATLGGAGHARGILER---GGRVIGLDQDPEAVARAKGL 63 >1HL3-A nrPDB Length = 358 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 13/24 (54%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAG 216 G T + GLG VG + + KA G Sbjct: 171 GETLGIIGLGRVGQAVALRAKAFG 194 >3HDH-A nrPDB Length = 302 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 V G G +G A G ++ VD +D AK+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >3JTJ-A nrPDB Length = 253 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 39/123 (31%), Gaps = 8/123 (6%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK--- 248 PG A + + + A+GA R+I + D + G C+ D++ Sbjct: 20 PGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGT 79 Query: 249 KPIQEVLKEMTDGGVDFSFEVIGRLDT-----MMASLLCCHEACGTSVIVGVPPDSQNLS 303 + + EV++ D V G + + VP S + Sbjct: 80 ERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEA 139 Query: 304 MNP 306 NP Sbjct: 140 FNP 142 >6APH-A nrPDB Length = 445 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 16/45 (35%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDK-FAKAKE 235 G V G G VG + AG + + +I+ A E Sbjct: 225 AGKRVVVCGFGDVGKGTAASFRGAG-SIVTVTEIDPICALQAAME 268 >3TNL-A nrPDB Length = 315 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 34/90 (37%), Gaps = 10/90 (11%) Query: 179 TGYGSAVNVAK-VTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 TGY A+ A G + G GG + + G I + D +A A++ Sbjct: 139 TGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFNRKDDFYANAEK-- 196 Query: 238 ATECINPQD-------YKKPIQEVLKEMTD 260 E IN + + +++ KE+ + Sbjct: 197 TVEKINSKTDCKAQLFDIEDHEQLRKEIAE 226 >3OC4-A nrPDB Length = 452 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 14/28 (50%) Query: 182 GSAVNVAKVTPGSTCAVFGLGGVGLSAI 209 G+ V + T AV G G +G+ AI Sbjct: 136 GALAAVPLLENSQTVAVIGAGPIGMEAI 163 >5J9G-A nrPDB Length = 338 Score = 28.9 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 23/57 (40%), Gaps = 1/57 (1%) Query: 244 PQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300 + Y +P + + + + GVDF E G T A +A V++ P + Sbjct: 76 YRVYAEPQAQNIPWVKNDGVDFVLECTG-FYTSKAKSQAHLDAGVKRVLISAPAGND 131 >3OJO-A nrPDB Length = 431 Score = 28.9 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%) Query: 193 GSTCAVFGLGGVGL-SAIMGCKAAGAARIIAVDINKDKFAK 232 GS V GLG +GL ++IM K ++ VDIN+ K Sbjct: 11 GSKLTVVGLGYIGLPTSIMFAKH--GVDVLGVDINQQTIDK 49 >4ZV2-A nrPDB Length = 233 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 57/152 (37%), Gaps = 23/152 (15%) Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMM 277 +++ DI+ K A AK+LG P D+ ++ + G +D + + Sbjct: 30 GKLVGFDIDLAK-AIAKKLGVKVEFKPMDFDG----IIPALQSGKIDVVIAGMTITEERK 84 Query: 278 ASLLCCHEA--CGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVAD 335 + G +++V N S+ + L G+ + G S++ V K+ D Sbjct: 85 KQVDFSDPYFEAGQAIVV----KKGNDSIKSLEDLKGKKV--GVQLGSTSEQHVKKVAKD 138 Query: 336 FMAKKFSLDALITHVLPFEKINEGFDLLHSGK 367 K V F+ +E F L SG+ Sbjct: 139 AGVK----------VKKFDNFSEAFQELKSGR 160 >3OND-A nrPDB Length = 488 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKA 233 G V G G VG K AGA R+I +I+ +A Sbjct: 264 AGKVAVVAGYGDVGKGCAAALKQAGA-RVIVTEIDPICALQA 304 >6ABI-A nrPDB Length = 358 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 16/49 (32%), Gaps = 1/49 (2%) Query: 218 ARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFS 266 +II DI K+ GA K + E +T G D Sbjct: 27 TKIIFFDIKDYDKEFFKKYGADYNFEMTFLKVRLTEETANLT-KGYDVV 74 >4DIM-A nrPDB Length = 403 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 23/72 (31%), Gaps = 6/72 (8%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDK--FAKAKELGATECINPQDYKKPI 251 + G G L K G I N K A E+ + NP + Sbjct: 8 KRLLILGAGRGQLGLYKAAKELGIHTIAGTMPNAHKPCLNLADEISYMDISNP----DEV 63 Query: 252 QEVLKEMTDGGV 263 ++ +K++ G Sbjct: 64 EQKVKDLNLDGA 75 >1F14-A nrPDB Length = 310 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 194 STCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKE 235 V G G +G A G ++ VD +D AK+K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >3JTM-A nrPDB Length = 351 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 17/49 (34%), Gaps = 1/49 (2%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATEC 241 G T G G +G + K G ++ D + KE GA Sbjct: 164 GKTIGTVGAGRIGKLLLQRLKPFG-CNLLYHDRLQMAPELEKETGAKFV 211 >5VJ7-A nrPDB Length = 476 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 47/122 (38%), Gaps = 11/122 (9%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252 G A+ G G GL+ G I +++ G E P++ ++ Sbjct: 154 GKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLT--YGIPEFRLPKEI---LR 208 Query: 253 EVLKEMTDGGVDFSFE-VIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLT 311 + LK+++ GV+ + ++G+ T+ L +V +G + L P + L Sbjct: 209 KELKKLSLLGVEIKTDHIVGKTITIQELLQEYD-----AVFIGTGAGTPKLPNIPGINLN 263 Query: 312 GR 313 G Sbjct: 264 GI 265 >3H9U-A nrPDB Length = 436 Score = 28.9 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 19/45 (42%), Gaps = 2/45 (4%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINK-DKFAKAKE 235 G T V G G VG + GA R++ +++ + A E Sbjct: 210 AGKTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAME 253 >4P8R-A nrPDB Length = 339 Score = 28.5 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 29/177 (16%), Positives = 54/177 (30%), Gaps = 23/177 (12%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAV---------------DINKDKFAKAKEL-GA 238 + G G +G + I+ + D +F A E+ G Sbjct: 12 RVGINGFGRIGRVVFRAAQRRNDIEIVGINDLLDADYMAYMLKYDSTHGRFEGAVEVQGG 71 Query: 239 TECINPQDYKKPIQE--VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP 296 +N + + + + + VD E G + + VI G Sbjct: 72 ALVVNGKKIRVTSERDPANLKWNEINVDVVVESTGLFLSDDTARKHIQAGAKKVVITG-- 129 Query: 297 PDSQNLSMNPMLLLTGRTWKGAILGGFKS--KECVPKLVADFMAKKFSLDALITHVL 351 P + M ++ + T+KG + S C+ L K ++ L+T V Sbjct: 130 PSKDDTPMF-VMGVNHTTYKGEAIVSNASCTTNCLAPLAKVLNDKFGIVEGLMTTVH 185 >5B37-A nrPDB Length = 361 Score = 28.5 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 7/74 (9%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARI--IAVDINKDKFAKAKEL-GATECINPQDYKK 249 G AV GLG VG + C+ + D++ K + K L GAT + P + Sbjct: 169 GMKVAVQGLGNVGKN---LCRHLHEHDVQLFVSDVDPIKAEEVKRLFGAT-VVEPTEIYS 224 Query: 250 PIQEVLKEMTDGGV 263 ++ GG+ Sbjct: 225 LDVDIFAPCALGGI 238 >3LLV-A nrPDB Length = 141 Score = 28.5 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 36/91 (39%), Gaps = 8/91 (8%) Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI-NPQDYKKPIQEVL 255 V G G+ + AAG +++AVD +K+K ++ G I +P D + Sbjct: 10 IVIGSEAAGVGLVRELTAAG-KKVLAVDKSKEKIELLEDEGFDAVIADPTD-----ESFY 63 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEA 286 + + GV + G D +L + Sbjct: 64 RSLDLEGVSAVL-ITGSDDEFNLKILKALRS 93 >3LP6-A nrPDB Length = 174 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 12/76 (15%), Positives = 26/76 (34%), Gaps = 5/76 (6%) Query: 149 QYTVVDENAVAKIDAASPLEK-----VCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGG 203 + + A + + G G S +++ ++ G A +GG Sbjct: 64 EVIIAGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGG 123 Query: 204 VGLSAIMGCKAAGAAR 219 G + ++ + GAA Sbjct: 124 AGNAGLLAVRMLGAAN 139 >1G6Q-1 nrPDB Length = 328 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 18/34 (52%), Gaps = 2/34 (5%) Query: 203 GVGLSAIMGCKAAGAARIIAVDINKDKFAKAKEL 236 G G+ ++ K GA +I VD++ AKEL Sbjct: 48 GTGILSMFAAKH-GAKHVIGVDMSSI-IEMAKEL 79 >2RIR-A nrPDB Length = 300 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 GS AV GLG G++ A GA + + A+ E+G Sbjct: 157 GSQVAVLGLGRTGMTIARTFAALGA-NVKVGARSSAHLARITEMG 200 >4IZO-A nrPDB Length = 419 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 16/36 (44%), Gaps = 1/36 (2%) Query: 192 PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINK 227 PG+ + G G +G +A G R+ +D + Sbjct: 34 PGAWLGMVGGGQLGRMFCFAAQAMG-YRVAVLDPDP 68 >1AHH-A nrPDB Length = 255 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 18/144 (12%), Positives = 42/144 (29%), Gaps = 22/144 (15%) Query: 193 GSTCAVFGLG-GVGL-SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP 250 G + G G G+G AI A A ++ DIN D A ++ Sbjct: 11 GKCAIITGAGAGIGKEIAITFATA--GASVVVSDINADA--------ANHVVDE------ 54 Query: 251 IQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 310 ++++ ++ + + + ++V + + Sbjct: 55 ----IQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMAD 110 Query: 311 TGRTWKGAILGGFKSKECVPKLVA 334 R ++ + F + V + Sbjct: 111 FRRAYELNVFSFFHLSQLVAPEME 134 >3DOC-A nrPDB Length = 335 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 42/133 (31%), Gaps = 27/133 (20%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINK-----------------DKFAKAKELG 237 A+ G G +G + + +G I V IN +F K E+ Sbjct: 4 RVAINGFGRIGRNILRAIVESGRTDIQVVAINDLGPVETNAHLLRYDSVHGRFPKEVEVA 63 Query: 238 ATEC------INPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSV 291 I + P + KE VD + E G T EA V Sbjct: 64 GDTIDVGYGPIKVHAVRNPAELPWKEEN---VDIALECTGIF-TSRDKAALHLEAGAKRV 119 Query: 292 IVGVPPDSQNLSM 304 IV P D +L++ Sbjct: 120 IVSAPADGADLTV 132 >1WY7-A nrPDB Length = 207 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 3/70 (4%) Query: 162 DAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARII 221 + LE+ G S A ++ + G A G G G+ + G GA +I Sbjct: 20 NPKVWLEQYRTPGNAASELLWLAYSLGDIE-GKVVADLGAGT-GVLSY-GALLLGAKEVI 76 Query: 222 AVDINKDKFA 231 V+++K+ Sbjct: 77 CVEVDKEAVD 86 >3HWR-A nrPDB Length = 318 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 30/102 (29%), Gaps = 5/102 (4%) Query: 193 GSTCAVFGLGGVGL-SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPI 251 G A+ G G VG M +A +I + + G D + + Sbjct: 19 GMKVAIMGAGAVGCYYGGMLARA--GHEVILIA-RPQHVQAIEATGLRLETQSFDEQVKV 75 Query: 252 QEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV 293 G D + DT A+L A S +V Sbjct: 76 SASSDPSAVQGADLVLFCVKSTDTQSAAL-AMKPALAKSALV 116 >1YPF-A nrPDB Length = 336 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 7/60 (11%) Query: 189 KVTPGSTCAV-----FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK--ELGATEC 241 + PG C FG GG L+A+ C A + IIA + AK GAT Sbjct: 177 GIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTNGDVAKSIRFGATMV 236 >2QHR-L nrPDB Length = 218 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 17/43 (39%) Query: 264 DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNP 306 D + + G DT+ + ++G P + L++ P Sbjct: 86 DEAIYICGVGDTIKEQFVYVFGGGTKVTVLGQPKSTPTLTVFP 128 >2X36-A nrPDB Length = 207 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 41/113 (36%), Gaps = 15/113 (13%) Query: 149 QYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSA 208 Y V + + + + GC T +++A P V + Sbjct: 81 DYLVTSHIHL-HVPEGATPKDGPSAGCTIVTA---LLSLAMGRP-----------VRQNL 125 Query: 209 IMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDG 261 M + + +I+ V K+K AK G T + P + KK ++ +T+G Sbjct: 126 AMTGEVSLTGKILPVGGIKEKTIAAKRAGVTCIVLPAENKKDFYDLAAFITEG 178 >1V9C-A nrPDB Length = 218 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 37/104 (35%), Gaps = 10/104 (9%) Query: 205 GLSAIM-GCKAAGAARIIAVDINKDKFAK----AKELGATECINPQDYKKP----IQEVL 255 GL AI G + AR+IA +N ++ EL A + + V Sbjct: 59 GLKAIQAGARILVDARMIACGLNPERLRLFGNEVVELLAHPEVVARAKATGGTRAEAAVA 118 Query: 256 KEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIV-GVPPD 298 G +D + +G T + +L+ +V G+P Sbjct: 119 YAWEKGLLDGAIVGVGNAPTFLLALVEAIRQGARPALVLGMPVG 162 >5J46-A nrPDB Length = 189 Score = 28.1 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 21/47 (44%), Gaps = 9/47 (19%) Query: 199 FGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 245 + G+GL+A R+I +D+++DK INP+ Sbjct: 62 YAAPGIGLAATQVDVH---ERVIVIDVSEDKNEL------RAFINPE 99 >2GMH-A nrPDB Length = 584 Score = 28.1 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 23/68 (33%), Gaps = 2/68 (2%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255 + G G GLSA K A D+ KA +GA + +E+ Sbjct: 38 VVIVGAGPAGLSAATRLKQLAAQH--EKDLRVCLVEKAAHIGAHTLSGACLDPRAFEELF 95 Query: 256 KEMTDGGV 263 + + G Sbjct: 96 PDWKEKGA 103 >5JFC-L nrPDB Length = 474 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 10/29 (34%) Query: 193 GSTCAVFGLGGVGLSAIMGCKAAGAARII 221 G A+ G G GL+ G I Sbjct: 154 GKKVAIIGAGPAGLTCAADLAKMGYEVTI 182 >4GCM-A nrPDB Length = 312 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 37/224 (16%), Positives = 61/224 (27%), Gaps = 57/224 (25%) Query: 196 CAVFGLGGVGLSAIMGCKAA--------------------------GAARIIAVDINKDK 229 A+ G G G++A + A G I D++ Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKM 68 Query: 230 FAKAKELGATE---------------CINPQDYKKPIQEVL----KEMTDGGVDFSFEVI 270 F AK+ GA IN + + + V+ E GV E+ Sbjct: 69 FEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELG 128 Query: 271 GRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVP 330 GR + A ++G + T + + Sbjct: 129 GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIV-----HRRDELRAQ 183 Query: 331 KLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILM 374 +++ D K +D + +H L INE GK L Sbjct: 184 RILQDRAFKNDKIDFIWSHTLK--SINE-----KDGKVGSVTLT 220 >3NNK-A nrPDB Length = 411 Score = 28.1 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 15/42 (35%) Query: 172 LIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCK 213 ++ G S A+ V+ + PG V G G + Sbjct: 67 MLVDGTSRAGIEAILVSAIRPGDKVLVPVFGRFGHLLCEIAR 108 >3T4P-A nrPDB Length = 334 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 24/67 (35%), Gaps = 3/67 (4%) Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAV---DINKDKFAKAKELG 237 Y A K+ PG + V G ++ A ++I ++ ++ + G Sbjct: 59 YDKAEKEGKLIPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFG 118 Query: 238 ATECINP 244 A + P Sbjct: 119 AEVILTP 125 >1LSS-A nrPDB Length = 140 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 29/83 (34%) Query: 163 AASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIA 222 + E L+ G T + + AV G V L + + K+ G + IA Sbjct: 41 KKASAEIDALVINGDCTKIKTLEDAGIEDADMYIAVTGKEEVNLMSSLLAKSYGINKTIA 100 Query: 223 VDINKDKFAKAKELGATECINPQ 245 + + LG ++P+ Sbjct: 101 RISEIEYKDVFERLGVDVVVSPE 123 >4P4L-A nrPDB Length = 277 Score = 28.1 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 44/141 (31%), Gaps = 7/141 (4%) Query: 197 AVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG-----ATEC--INPQDYKK 249 V G GG +A++G G I V N DK A+ +LG AT + Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATRFCAFDSGGLAD 180 Query: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLL 309 + ++ + + G L + L ++ T + V + +L Sbjct: 181 AVAAAEVLVSTIPAEVAAGYAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGGRVISGLQML 240 Query: 310 LTGRTWKGAILGGFKSKECVP 330 L + G + Sbjct: 241 LHQAFAQVEQFTGLPAPREAM 261 >3RHA-A nrPDB Length = 482 Score = 28.1 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 11/23 (47%) Query: 196 CAVFGLGGVGLSAIMGCKAAGAA 218 + G G GL+A K AG + Sbjct: 10 VVIVGAGPSGLTAARELKKAGLS 32 >3GG9-A nrPDB Length = 352 Score = 28.1 bits (61), Expect = 7.2, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 24/60 (40%), Gaps = 2/60 (3%) Query: 178 STGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG 237 ST + +V G T +FG G +G +A G + V ++ +A+ G Sbjct: 145 STTMPPNFGIGRVLKGQTLGIFGYGKIGQLVAGYGRAFGMN--VLVWGRENSKERARADG 202 >4FHN-X nrPDB Length = 450 Score = 27.8 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 22/56 (39%), Gaps = 7/56 (12%) Query: 178 STGYG------SAVNVAKVT-PGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDIN 226 +TGYG + + + G +V G G V AI GA I A D + Sbjct: 213 ATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSS 268 >4F86-A nrPDB Length = 320 Score = 27.8 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 24/64 (37%), Gaps = 6/64 (9%) Query: 186 NVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAK----AKELGATEC 241 ++ V PG T G G G + ++ V ++ + A+ELG + Sbjct: 119 HLGPVGPGDTLVDAGCGRGGSMVM--AHQRFGCKVEGVTLSAAQAEFGNRRARELGIDDH 176 Query: 242 INPQ 245 + + Sbjct: 177 VRSR 180 >4KIC-A nrPDB Length = 357 Score = 27.8 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 38/195 (19%), Positives = 67/195 (34%), Gaps = 24/195 (12%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKA-KELGA 238 + +AV+ TP +T A G G G I + R + VDI A A KE+ A Sbjct: 167 AFWAAVDGLGYTP-TTVADLGSG-SGERLIQIARRFPGVRGLGVDIADGAIAMAEKEVAA 224 Query: 239 TECINPQDYKKPIQEVLKEMTDGG----VDFSF------------EVIGRLDTMMASLLC 282 + + + + +++ G VD + L + A+ Sbjct: 225 KGFGDQISFVRGDARTIDQVSARGEFAEVDLLTCFMMGHDFWPRENCVQTLRKLRAAFPN 284 Query: 283 CHEA--CGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKK 340 + VG+P + L + + G G L + V + KK Sbjct: 285 VRRFLLGDATRTVGIP--DRELPVFTLGFEFGHDMMGVYLPTLDEWDGVFEEGGWRCVKK 342 Query: 341 FSLDAL-ITHVLPFE 354 ++D+L ++ V E Sbjct: 343 HAIDSLSVSVVFELE 357 >1S4D-A nrPDB Length = 280 Score = 27.8 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 18/44 (40%), Gaps = 4/44 (9%) Query: 195 TCAVFGLGGV--GLSAIMGCKAAGAARIIAVD--INKDKFAKAK 234 + + G G GL + A A +I D +N+D A+ Sbjct: 16 SVWLVGAGPGDPGLLTLHAANALRQADVIVHDALVNEDCLKLAR 59 >3AOE-E nrPDB Length = 419 Score = 27.8 bits (60), Expect = 8.4, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 24/61 (39%), Gaps = 7/61 (11%) Query: 184 AVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDIN------KDKFAKAKELG 237 A G+ V GLG VG + + + G R++AV + + A+ L Sbjct: 209 AKRRGLDLRGARVVVQGLGQVGAAVALHAERLGM-RVVAVATSMGGMYAPEGLDVAEVLS 267 Query: 238 A 238 A Sbjct: 268 A 268 >3T5Y-A nrPDB Length = 357 Score = 27.8 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 10/24 (41%) Query: 180 GYGSAVNVAKVTPGSTCAVFGLGG 203 G V A V PG +FG G Sbjct: 304 GLAHLVENALVQPGDRVLLFGGGA 327 >3PPI-A nrPDB Length = 281 Score = 27.8 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 27/81 (33%), Gaps = 3/81 (3%) Query: 200 GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELG--ATEC-INPQDYKKPIQEVLK 256 G GG+G + + A G +IA + A A ELG A N + + Sbjct: 38 GAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSVLAAIEA 97 Query: 257 EMTDGGVDFSFEVIGRLDTMM 277 G + ++ G Sbjct: 98 ANQLGRLRYAVVAHGGFGVAQ 118 >4DZR-A nrPDB Length = 215 Score = 27.8 bits (60), Expect = 8.9, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 24/60 (40%), Gaps = 6/60 (10%) Query: 184 AVNVAKVTP-GSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK----ELGA 238 A+ K P G+ G G G A+ A + AVD++ D A A+ GA Sbjct: 21 AIRFLKRMPSGTRVIDVGTG-SGCIAVSIALACPGVSVTAVDLSMDALAVARRNAERFGA 79 >3A26-A nrPDB Length = 301 Score = 27.8 bits (60), Expect = 8.9, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 21/48 (43%), Gaps = 1/48 (2%) Query: 185 VNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAK 232 V +AKV V G+G ++ G A++IA++ + F Sbjct: 140 VRMAKVAKPDELVVDMFAGIGHLSLPIA-VYGKAKVIAIEKDPYTFKF 186 >1MV8-A nrPDB Length = 436 Score = 27.8 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAK 232 ++FGLG VG + GC +A +I VD++ K Sbjct: 2 RISIFGLGYVG-AVCAGCLSARGHEVIGVDVSSTKIDL 38 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.131 0.358 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,186,156 Number of Sequences: 36641 Number of extensions: 599413 Number of successful extensions: 3489 Number of sequences better than 10.0: 350 Number of HSP's better than 10.0 without gapping: 281 Number of HSP's successfully gapped in prelim test: 181 Number of HSP's that attempted gapping in prelim test: 2558 Number of HSP's gapped (non-prelim): 545 length of query: 375 length of database: 10,336,785 effective HSP length: 99 effective length of query: 276 effective length of database: 6,709,326 effective search space: 1851773976 effective search space used: 1851773976 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.8 bits)