BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07288 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3QUM-P nrPDB 490 e-139 4NFE-A nrPDB 398 e-111 1SPJ-A nrPDB 308 2e-84 1GVZ-A nrPDB 288 2e-78 1SGF-G nrPDB 269 8e-73 1TON-A nrPDB 266 6e-72 1AO5-A nrPDB 261 2e-70 1SGF-A nrPDB 256 5e-69 1NPM-A nrPDB 213 8e-56 2PKA-B nrPDB 198 2e-51 4WWY-A nrPDB 196 6e-51 2PSX-A nrPDB 195 1e-50 5MS3-A nrPDB 192 9e-50 5C67-A nrPDB 192 2e-49 1A0J-A nrPDB 192 2e-49 1F7Z-A nrPDB 191 3e-49 4AN7-A nrPDB 188 2e-48 5FXL-A nrPDB 186 6e-48 3BSQ-A nrPDB 182 2e-46 6QHB-A nrPDB 180 5e-46 1UTJ-A nrPDB 177 3e-45 5ZFH-A nrPDB 177 3e-45 2EEK-A nrPDB 177 6e-45 2BDH-A nrPDB 173 6e-44 2TLD-E nrPDB 172 2e-43 1FXY-A nrPDB 171 2e-43 4E7N-A nrPDB 159 1e-39 2AIQ-A nrPDB 157 4e-39 1FDP-A nrPDB 152 2e-37 4GSO-A nrPDB 149 9e-37 1EUF-A nrPDB 148 2e-36 1OP0-A nrPDB 147 3e-36 1BQY-A nrPDB 146 7e-36 1MZD-A nrPDB 145 2e-35 3S9B-A nrPDB 144 4e-35 5LPF-A nrPDB 143 8e-35 3S69-A nrPDB 141 3e-34 1ORF-A nrPDB 141 3e-34 1NN6-A nrPDB 140 4e-34 2CGA-A nrPDB 139 1e-33 3G01-A nrPDB 138 3e-33 5UGG-A nrPDB 135 3e-32 3E0N-B nrPDB 134 3e-32 3DFJ-A nrPDB 134 4e-32 5TJX-A nrPDB 134 5e-32 5FCR-A nrPDB 132 1e-31 4DUR-A nrPDB 131 2e-31 1FI8-A nrPDB 130 6e-31 2RDL-A nrPDB 129 1e-30 3RP2-A nrPDB 128 3e-30 1AZZ-A nrPDB 127 4e-30 3T2N-A nrPDB 127 5e-30 6I44-A nrPDB 126 8e-30 1FUJ-A nrPDB 126 8e-30 1BRU-P nrPDB 125 2e-29 5XRF-A nrPDB 125 2e-29 3TK9-A nrPDB 124 3e-29 1X7A-C nrPDB 123 6e-29 1P57-B nrPDB 123 7e-29 2F83-A nrPDB 123 8e-29 4MPW-A nrPDB 123 1e-28 1LTO-A nrPDB 122 1e-28 1SC8-U nrPDB 122 1e-28 3LC3-A nrPDB 122 1e-28 4Q7Y-A nrPDB 122 1e-28 6AOD-C nrPDB 122 1e-28 4DGJ-A nrPDB 119 9e-28 2ZKS-A nrPDB 119 1e-27 4Z6A-H nrPDB 119 2e-27 1IAU-A nrPDB 117 4e-27 1YC0-A nrPDB 117 5e-27 1KYN-A nrPDB 116 8e-27 1EKB-B nrPDB 115 1e-26 2R0L-A nrPDB 115 2e-26 3W94-A nrPDB 115 3e-26 3F6U-H nrPDB 114 4e-26 1AE5-A nrPDB 114 4e-26 4H4F-A nrPDB 112 2e-25 5GVT-A nrPDB 111 3e-25 2V35-A nrPDB 110 4e-25 4IGD-A nrPDB 110 6e-25 1PYT-D nrPDB 110 6e-25 5LHN-A nrPDB 109 1e-24 4DJZ-B nrPDB 108 3e-24 4XDE-A nrPDB 108 3e-24 3P8G-A nrPDB 106 9e-24 1A5I-A nrPDB 106 1e-23 1BDA-A nrPDB 106 1e-23 2OCV-B nrPDB 105 2e-23 2OQ5-A nrPDB 104 3e-23 2XRC-A nrPDB 104 4e-23 5KWM-A nrPDB 104 4e-23 1PPF-E nrPDB 104 4e-23 2F91-A nrPDB 104 4e-23 1ELT-A nrPDB 103 5e-23 5O32-I nrPDB 103 7e-23 1FON-A nrPDB 102 1e-22 1EQ9-A nrPDB 102 1e-22 1SI5-H nrPDB 102 2e-22 1MKW-K nrPDB 101 3e-22 1AKS-B nrPDB 101 4e-22 3K65-B nrPDB 101 4e-22 3NXP-A nrPDB 101 4e-22 4NZQ-A nrPDB 100 7e-22 1ETT-H nrPDB 99 1e-21 1PQ7-A nrPDB 98 3e-21 2KAI-A nrPDB 98 4e-21 1FIZ-A nrPDB 98 5e-21 1VR1-H nrPDB 97 6e-21 1FIW-A nrPDB 97 8e-21 5XW8-A nrPDB 96 1e-20 1Q3X-A nrPDB 96 2e-20 1KIG-H nrPDB 95 2e-20 1C5M-D nrPDB 95 3e-20 1YM0-A nrPDB 95 3e-20 4FXG-H nrPDB 93 1e-19 1ZJK-A nrPDB 93 1e-19 2XXL-A nrPDB 92 2e-19 2OLG-A nrPDB 92 3e-19 5TO3-B nrPDB 90 9e-19 4KKD-A nrPDB 87 6e-18 4LK4-A nrPDB 86 1e-17 4IW4-E nrPDB 86 1e-17 2HLC-A nrPDB 84 5e-17 4BXW-A nrPDB 80 8e-16 6BQM-A nrPDB 77 5e-15 2B9L-A nrPDB 77 8e-15 2ASU-B nrPDB 76 2e-14 2JET-B nrPDB 76 2e-14 5UBM-A nrPDB 74 8e-14 1MD7-A nrPDB 72 2e-13 1ELV-A nrPDB 72 2e-13 2QY0-B nrPDB 72 2e-13 3RU4-E nrPDB 72 3e-13 1GPZ-A nrPDB 71 4e-13 4J1Y-A nrPDB 71 6e-13 3VGC-B nrPDB 70 6e-13 3H7T-A nrPDB 69 2e-12 1M9U-A nrPDB 68 4e-12 2JET-C nrPDB 67 6e-12 2FMJ-A nrPDB 67 7e-12 3H7O-A nrPDB 67 8e-12 4X0L-C nrPDB 66 1e-11 3I77-A nrPDB 65 2e-11 4WJG-C nrPDB 65 3e-11 2I6S-A nrPDB 62 2e-10 4F4O-C nrPDB 62 2e-10 1RIW-B nrPDB 60 1e-09 3BEU-A nrPDB 59 1e-09 1BBR-H nrPDB 59 3e-09 1BBR-E nrPDB 54 7e-08 2HNT-F nrPDB 53 1e-07 1EPT-B nrPDB 49 2e-06 2WIN-I nrPDB 49 2e-06 1DLE-A nrPDB 49 2e-06 2OK5-A nrPDB 49 2e-06 3F1S-B nrPDB 47 9e-06 3H5C-B nrPDB 45 3e-05 2HNT-C nrPDB 42 3e-04 1P3E-A nrPDB 29 2.4 3ARQ-A nrPDB 28 5.5 2EA3-A nrPDB 28 5.8 6BXJ-A nrPDB 27 9.2 >3QUM-P nrPDB Length = 237 Score = 490 bits (1262), Expect = e-139, Method: Compositional matrix adjust. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 237 >4NFE-A nrPDB Length = 237 Score = 398 bits (1023), Expect = e-111, Method: Compositional matrix adjust. Identities = 188/237 (79%), Positives = 210/237 (88%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGGWECEKHSQPWQV V S G A CGGVLVHPQWVLTAAHC++ S + LGRH+LF PE Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 DTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHDLMLLRLSEPA++TD VKV+ LPTQ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EPALGTTCYASGWGSIEPEEFL P+ LQCV LH++SND+CA+ + +KVT+FMLCAG WTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P++YTKVVHYRKWIKDTI ANP Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 237 >1SPJ-A nrPDB Length = 238 Score = 308 bits (788), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 145/237 (61%), Positives = 176/237 (74%), Gaps = 1/237 (0%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGGWECE+HSQPWQ + CGG+LVH QWVLTAAHCI + + LGRH+LF E Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE-LTDAVKVMDLPT 143 +T Q VS SFPHP ++MSLL+N + +D SHDLMLLRL+EPA+ +TDAVKV++LPT Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203 +EP +G+TC ASGWGSIEPE F P LQCVDL ++ ND C + H QKVT FMLC G Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK TC GDSGGPL+C+GVLQG+TSWG PC P +PS+ +V+ Y KWI+DTI N Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 237 >1GVZ-A nrPDB Length = 237 Score = 288 bits (736), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 138/236 (58%), Positives = 171/236 (72%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+GGWECEKHS+PWQV V +G CGGVLVHPQWVLTAAHC+ + I LGRH+L E Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 DT Q QVS SF P +D+SLLK ++LRP DD SHDLMLLRL++PA +TDAVK++DLPTQ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EP LG+TCY SGWG I LQCV+L + SN+ CA+ +P+K+T+F+LCA Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 S C GDSGG L+C+GV QGITSWG CA ++TKV+ ++KWIK+TI N Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >1SGF-G nrPDB Length = 237 Score = 269 bits (688), Expect = 8e-73, Method: Compositional matrix adjust. Identities = 131/239 (54%), Positives = 169/239 (70%), Gaps = 4/239 (1%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG++CEK+SQPW V V + +CGGVL+ P WVLTAAHC + + LG+++LF E Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKN--RFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 + Q VS + PHP ++MSL++ RFL D S+DLMLLRLS+PA++TD VK + LP Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEY--DYSNDLMLLRLSKPADITDTVKPITLP 118 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 T+EP LG+TC ASGWGSI P +F L CV+L ++ N+ CA+ H +KVT MLCAG Sbjct: 119 TEEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEM 178 Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GGK TC GDSGGPL+C+GVLQGITSWG PC P+ P +YTK+ + WIKDT+ NP Sbjct: 179 DGGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKNP 237 >1TON-A nrPDB Length = 235 Score = 266 bits (680), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 126/237 (53%), Positives = 165/237 (69%), Gaps = 2/237 (0%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG++CEK+SQPWQV V + +CGGVL+ P WV+TAAHC N +LLGR++LF E Sbjct: 1 IVGGYKCEKNSQPWQVAVINE--YLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q V SF HP Y ++ N +P D S+DLMLL LSEPA++T VKV+DLPT+ Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EP +G+TC ASGWGS P E + LQCV++H++SN+ C + + VT MLCAG G Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GK TC+GDSGGPL+C+GVLQGITS G+ PCA P+ P++Y K++ + WIK + NP Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP 235 >1AO5-A nrPDB Length = 237 Score = 261 bits (668), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 125/236 (52%), Positives = 165/236 (69%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 +VGG+ CEK+SQPWQV V + +CGGVL+ WVLTAAHC ++ + LG++ LF E Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q VS SFPHP ++MSLL + + PG D S DLMLLRLS+PA++TD VK + LPT+ Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EP G+ C ASGWGSI P + P LQCV + ++ N+ CA+V+ QKVT MLCAG G Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK TC DSGGPL+C+G+LQG TS+G PC P P++YT ++ + WIKDT++ N Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >1SGF-A nrPDB Length = 240 Score = 256 bits (655), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 125/245 (51%), Positives = 165/245 (67%), Gaps = 5/245 (2%) Query: 17 AAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLG 76 AAP + S++ +CE +SQPW V V + CGGVL+ WVLTAAHC +K + LG Sbjct: 1 AAPPVQSQV----DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLG 55 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 +++ E + Q VS + PHP ++MSLL +P DD S+DLMLLRLS+PA++TD V Sbjct: 56 KNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVV 115 Query: 137 KVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 K + LPT+EP LG+TC ASGWGS P +F P LQCV+L ++ N+ C + H KVT M Sbjct: 116 KPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAM 175 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 LCAG GG TC DSGGPL+C+G+LQGITSWG EPC P PS+YTK++ + WI++T Sbjct: 176 LCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRET 235 Query: 257 IVANP 261 + NP Sbjct: 236 MANNP 240 >1NPM-A nrPDB Length = 225 Score = 213 bits (541), Expect = 8e-56, Method: Compositional matrix adjust. Identities = 108/233 (46%), Positives = 142/233 (60%), Gaps = 9/233 (3%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G EC HSQPWQ + R +CGGVLV +WVLTAAHC + K + LG HSL + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q QV+ S HP Y+ S P +D SHD+ML+RL A L D VK + L Sbjct: 61 QPEQEIQVAQSIQHPCYNNS-------NP-EDHSHDIMLIRLQNSANLGDKVKPVQLANL 112 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 P +G C SGWG++ + P L C ++ + S + C + +P K+T+ M+CAG + Sbjct: 113 CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS-SN 171 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G TC GDSGGPLVC+G+LQGITSWGS+PC PE+P +YTK+ Y WIK T+ Sbjct: 172 GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >2PKA-B nrPDB Length = 152 Score = 198 bits (504), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 94/150 (62%), Positives = 112/150 (74%), Gaps = 2/150 (1%) Query: 114 GDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEP--EEFLTPKKL 171 G D SHDLMLLRL PA++TDAVKV++LPTQEP LG+TC ASGWGSIEP ++F P ++ Sbjct: 3 GKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDEI 62 Query: 172 QCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS 231 QCV L ++ N CA HP KVT+ MLCAG GGK TC GDSGGPL+CNG+ QGITSWG Sbjct: 63 QCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGH 122 Query: 232 EPCALPERPSLYTKVVHYRKWIKDTIVANP 261 PC +PS+YTK++ Y WI DTI NP Sbjct: 123 TPCGSANKPSIYTKLIFYLDWIDDTITENP 152 >4WWY-A nrPDB Length = 224 Score = 196 bits (499), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 101/236 (42%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ CE++S P+QV + S G CGG L++ QWV++A HC +++ + LG H++ E Sbjct: 1 IVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + HP YD L N D+ML++LS A + V + LPT Sbjct: 60 GNEQFINAAKIIRHPQYDRKTLNN-----------DIMLIKLSSRAVINAHVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 PA GT C SGWG+ P +LQC+D V+S C +P K+T M C G G Sbjct: 109 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEG 168 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C DSGGP+VCNG LQG+ SWG + CA +P +YTKV +Y KWIK+TI AN Sbjct: 169 GKDSCQRDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >2PSX-A nrPDB Length = 227 Score = 195 bits (496), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 101/238 (42%), Positives = 144/238 (60%), Gaps = 14/238 (5%) Query: 25 IVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 I+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 84 EDTGQ-VFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 ++GQ +FQ S PHP Y PG S+DLML++L+ T V+ +++ Sbjct: 61 YESGQQMFQGVKSIPHPGYS---------HPGH--SNDLMLIKLNRRIRPTKDVRPINVS 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 + P+ GT C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG Sbjct: 110 SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD- 168 Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 G+ +C GDSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN Sbjct: 169 KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >5MS3-A nrPDB Length = 228 Score = 192 bits (489), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 99/233 (42%), Positives = 132/233 (56%), Gaps = 9/233 (3%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC + K + LG HSL + + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q V S PHP Y+ S + +D +HDLMLL+L + A L VK + L Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLADH 112 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 G C SGWG++ P L C ++ + C +P ++T M+CAG + Sbjct: 113 CTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SK 171 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK I Sbjct: 172 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >5C67-A nrPDB Length = 224 Score = 192 bits (487), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 100/236 (42%), Positives = 134/236 (56%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ CE++S P+QV + S G CGG L+ QWV++AAHC + + + LG H++ E Sbjct: 1 IVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + HP Y+ L N D+ML++LS PA + V + LPT Sbjct: 60 GNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIKLSSPAVINARVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 PA GT C SGWG+ P +L+C+D V++ C +P K+T M C G G Sbjct: 109 PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEG 168 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C D+GGP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDTI AN Sbjct: 169 GKDSCQRDAGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >1A0J-A nrPDB Length = 223 Score = 192 bits (487), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 96/236 (40%), Positives = 135/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+EC K+S +Q + S G CGG L+ WV++AAHC +++ + LG H++ E Sbjct: 1 IVGGYECRKNSASYQASLQS-GYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 T Q HP Y+ L N D+ML++LS+PA L V + LP+ Sbjct: 60 GTEQFIDSVKVIMHPSYNSRNLDN-----------DIMLIKLSKPASLNSYVSTVALPSS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 + GT C SGWG++ P L+C+DL ++S+ C +P ++T M CAG G Sbjct: 109 CASSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEG 168 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C GDSGGP+VCNG LQG+ SWG CA +P +YTKV +YR WI T+ +N Sbjct: 169 GKDSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1F7Z-A nrPDB Length = 233 Score = 191 bits (484), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 99/236 (41%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ C+++S P+QV + S G CGG L++ QWV++AAHC +++ + LG H++ E Sbjct: 11 IVGGYTCQENSVPYQVSLNS-GYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLE 69 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + HP +D L N D+ML++LS P +L V + LP+ Sbjct: 70 GNEQFVNAAKIIKHPNFDRKTLNN-----------DIMLIKLSSPVKLNARVATVALPSS 118 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 GT C SGWG+ P LQC+D ++ C +P K+T M+C G G Sbjct: 119 CAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEG 178 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C GDSGGP+VCNG LQGI SWG CALP+ P +YTKV +Y WI+DTI AN Sbjct: 179 GKDSCQGDSGGPVVCNGELQGIVSWGYG-CALPDNPGVYTKVCNYVDWIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 97/237 (40%), Positives = 135/237 (56%), Gaps = 13/237 (5%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +IVGG+ C +S P+QV + S G CGG L++ QWV++AAHC +++ + LG H++ Sbjct: 8 KIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVL 66 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 E Q + HP ++ + L N D+ML++LS PA L V + LP Sbjct: 67 EGNEQFINAAKIITHPNFNGNTLDN-----------DIMLIKLSSPATLNSRVATVSLPR 115 Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203 A GT C SGWG+ + P LQC+ V+S+ C +P ++T M+C G Sbjct: 116 SCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLE 175 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK +C GDSGGP+VCNG LQGI SWG CA +P +YTKV +Y WI+ TI AN Sbjct: 176 GGKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >5FXL-A nrPDB Length = 246 Score = 186 bits (473), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 95/237 (40%), Positives = 134/237 (56%), Gaps = 13/237 (5%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +IVGG+ C ++ P+QV + S G CGG L++ QWV++AAHC ++ + LG ++ Sbjct: 23 KIVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVV 81 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 E Q S S HP Y+ + L N D+ML++L A L V + LPT Sbjct: 82 EGNEQFISASKSIVHPSYNSNTLNN-----------DIMLIKLKSAASLNSRVASISLPT 130 Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203 + GT C SGWG+ + P L+C+ ++S+ C +P ++T M CAG Sbjct: 131 SCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLE 190 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK +C GDSGGP+VC+G LQGI SWGS CA +P +YTKV +Y WIK TI +N Sbjct: 191 GGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >3BSQ-A nrPDB Length = 227 Score = 182 bits (461), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 98/233 (42%), Positives = 131/233 (56%), Gaps = 13/233 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + S SF HP Y N DLML++L+ A L+ VK + LP++ Sbjct: 59 RRAQRIKASKSFRHPGYSTQTHVN-----------DLMLVKLNSQARLSSMVKKVRLPSR 107 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 GTTC SGWG+ + P L CVD+ +IS C +V+ + MLCAG Sbjct: 108 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 167 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 K+ C+GDSGGPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+ Sbjct: 168 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 220 >6QHB-A nrPDB Length = 223 Score = 180 bits (457), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 93/236 (39%), Positives = 135/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 +V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L E Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + + V + HP YD + D+MLLRL+ PA+L++ ++ + L Sbjct: 61 SSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPLERD 109 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 A T+C+ GWG +F P +QC +H++S + C +P ++T+ MLCAG Sbjct: 110 CSAQTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKY 167 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C GDSGGPLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A Sbjct: 168 GKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >1UTJ-A nrPDB Length = 242 Score = 177 bits (450), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 101/258 (39%), Positives = 142/258 (55%), Gaps = 19/258 (7%) Query: 3 VPVVFLTLSVTWIGAAPLILS-RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVL 61 + +VF+ L IGAA +IVGG+EC+ +SQP QV + S G CGG LV+ WV+ Sbjct: 2 ISLVFVLL----IGAAFATEDDKIVGGYECKPYSQPHQVSLNS-GYHFCGGSLVNENWVV 56 Query: 62 TAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDL 121 +AAHC +++ + LG H++ E + Q S HP Y + N D+ Sbjct: 57 SAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDN-----------DI 105 Query: 122 MLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISN 181 ML++LS+PA L V+ + LPT GT C SGWG+ KLQC+++ ++S Sbjct: 106 MLIKLSKPATLNTYVQPVALPTSCAPAGTMCTVSGWGNTMSST-ADSNKLQCLNIPILSY 164 Query: 182 DVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPS 241 C +P +T M CAG GGK +C GDSGGP+VCNG LQG+ SWG CA P P Sbjct: 165 SDCNNSYPGMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPG 223 Query: 242 LYTKVVHYRKWIKDTIVA 259 +Y KV + W+ T+ + Sbjct: 224 VYAKVCIFNDWLTSTMAS 241 >5ZFH-A nrPDB Length = 224 Score = 177 bits (450), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 90/233 (38%), Positives = 131/233 (56%), Gaps = 13/233 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G++C++ S PWQV + + CGGVLV WVLTAAHC + + LG + + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIG--D 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q + + SF HP Y N D+ML+RL EP +++ V+ + LP Sbjct: 59 QSAQKIKATKSFRHPGYSTKTHVN-----------DIMLVRLDEPVKMSSKVEAVQLPEH 107 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 GT+C SGWG+ + P L C D+ +IS+ C +V+ + K MLCAG Sbjct: 108 CEPPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS 167 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 +TC+GDSGGPLVCN LQG+ SWG+ PC P P +YT+V Y++W+ +T+ Sbjct: 168 KTNTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETM 220 >2EEK-A nrPDB Length = 220 Score = 177 bits (448), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 98/233 (42%), Positives = 130/233 (55%), Gaps = 14/233 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+EC KHSQ QV + S G CGG LV WV++AAHC ++ + LG H + E Sbjct: 1 IVGGYECTKHSQAHQVSLNS-GYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 T Q S HP Y + N D+ML++L++PA L V + LPT+ Sbjct: 60 GTEQYISSSSVIRHPNYSSYNINN-----------DIMLIKLTKPATLNQYVHAVALPTE 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 A T C SGWG+ KLQC+ L ++S+ CA +P +T+ M CAG G Sbjct: 109 CAADATMCTVSGWGNTM-SSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEG 167 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 GK +C GDSGGP+VCNGVLQG+ SWG CA + P +Y KV W++DT+ Sbjct: 168 GKDSCQGDSGGPVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTM 219 >2BDH-A nrPDB Length = 223 Score = 173 bits (439), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 95/236 (40%), Positives = 134/236 (56%), Gaps = 14/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL + Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 85 DTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 + G Q+ + S S HP Y+ LL N DLML++L E +D ++ + + + Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESVSESDTIRSISIAS 109 Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203 Q P G +C SGWG + P LQCV++ V+S +VC++++ M CAG Sbjct: 110 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQ 167 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 K +C+GDSGGPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A Sbjct: 168 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >2TLD-E nrPDB Length = 220 Score = 172 bits (435), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 93/236 (39%), Positives = 131/236 (55%), Gaps = 16/236 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ C ++ P+QV + S G CGG L++ QWV++AAHC ++ + LG ++ E Sbjct: 1 IVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q S S HP Y+ + L N D+ML++L A L V + LPT Sbjct: 60 GNEQFISASKSIVHPSYNSNTLNN-----------DIMLIKLKSAASLNSRVASISLPTS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 + GT C SGWG+ + P L+C+ ++S+ C +P ++T M CAG Sbjct: 109 CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLE-- 166 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 G +C GDSGGP+VC+G LQGI SWGS CA +P +YTKV +Y WIK TI +N Sbjct: 167 GGDSCQGDSGGPVVCSGKLQGIVSWGS-GCA-KNKPGVYTKVCNYVSWIKQTIASN 220 >1FXY-A nrPDB Length = 228 Score = 171 bits (434), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 95/239 (39%), Positives = 126/239 (52%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPWQ-VLVASRGRAVCGGVLVHPQWVLTAAHCI--RNKSVILLGRHSLF 81 IVGG+ C+ PWQ +L+ CGG ++ ++LTAAHC+ + + +G + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E V +V H NRF + D D+ +LRL P V L Sbjct: 61 QEEGGEAVHEVEVVIKH---------NRFTKETYD--FDIAVLRLKTPITFRMNVAPASL 109 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGR 201 PT PA GT C SGWG+ P +LQC+D V+S C +P K+T M C G Sbjct: 110 PTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGF 169 Query: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK +C GDSGGP+VCNG LQG+ SWG + CA +P +YTKV +Y KWIK+TI AN Sbjct: 170 LEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >4E7N-A nrPDB Length = 238 Score = 159 bits (403), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 95/241 (39%), Positives = 129/241 (53%), Gaps = 15/241 (6%) Query: 25 IVGGWECEKHSQPWQV-LVASRGRAV-CGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 I+GG EC + + V L SR R + CGG L++ +WVLTAAHC R I LG HS Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 P + Q P + KN L D+ML+RL P + + + LP Sbjct: 61 PNEDEQT-----RVPKEKFFCLSSKNYTLW-----DKDIMLIRLDSPVKNSKHIAPFSLP 110 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ---KVTKFMLCA 199 + P++G+ C GWG I P E P CV+++++ ++C +P+ T LCA Sbjct: 111 SSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCA 170 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 G GGK TC GDSGGPL+CNG QGI SWG +PCA P +P+ YTKV + WI++ I Sbjct: 171 GILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAG 230 Query: 260 N 260 N Sbjct: 231 N 231 >2AIQ-A nrPDB Length = 231 Score = 157 bits (397), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 87/238 (36%), Positives = 123/238 (51%), Gaps = 16/238 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC + + LV + G ++CGG L++ +WVLTA HC R I LG H+L Sbjct: 1 VIGGDECNINEHRFLALVYANG-SLCGGTLINQEWVLTARHCDRGNMRIYLGMHNL---- 55 Query: 85 DTGQVFQVS--HSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 +V FP Y +N + D+ML+RL+ P + + + LP Sbjct: 56 ---KVLNKDALRRFPKEKYFCLNTRNDTIW-----DKDIMLIRLNRPVRNSAHIAPLSLP 107 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 + P++G+ C GWG+I P C +++++ VC Q + + LCAG Sbjct: 108 SNPPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVC-QAAYKGLAATTLCAGIL 166 Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK TC GDSGGPL+CNG QGI S G PCA P +P +YTKV Y WI+ I N Sbjct: 167 EGGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >1FDP-A nrPDB Length = 235 Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 94/244 (38%), Positives = 135/244 (55%), Gaps = 23/244 (9%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN----KSVILLGRHS 79 RI+GG E E H++P+ V G +CGGVLV QWVL+AAHC+ + K +LLG HS Sbjct: 7 RILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHS 66 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L PE + +++ V + PHP D HDL+LL+LSE A L AV+ + Sbjct: 67 LSQPEPSKRLYDVLRAVPHPDSQP-----------DTIDHDLLLLQLSEKATLGPAVRPL 115 Query: 140 --DLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV--HPQKVTKF 195 ++ A GT C +GWG + P LQ V L V+ C + H +T+ Sbjct: 116 PWQRVDRDVAPGTLCDVAGWGIVN-HAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITER 174 Query: 196 MLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255 ++CA + + +C GDSGGPLVC GVL+G+ + GS C ++P +YT+V Y WI D Sbjct: 175 LMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI-D 231 Query: 256 TIVA 259 +++A Sbjct: 232 SVLA 235 >4GSO-A nrPDB Length = 232 Score = 149 bits (377), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 80/236 (33%), Positives = 120/236 (50%), Gaps = 11/236 (4%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC+ + P+ + S G CG L++ +WV+TAAHC + LG HS Sbjct: 1 VLGGDECDINEHPFLAFLYSHGY-FCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q F P +MS + ++ D+ML++L +P + + + LP+ Sbjct: 60 EDEQTRNPKEKFICPNKNMSEVLDK----------DIMLIKLDKPISNSKHIAPLSLPSN 109 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 P++G+ C GWGSI P C +++++ +VC + K LCAG G Sbjct: 110 PPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEG 169 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK TC GDSGGPL+CNG QGI S+G+ C +P +YT V Y WI+ I N Sbjct: 170 GKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >1EUF-A nrPDB Length = 227 Score = 148 bits (373), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 89/238 (37%), Positives = 128/238 (53%), Gaps = 20/238 (8%) Query: 25 IVGGWECEKHSQPWQ--VLVASRGRA-VCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E + HS+P+ +L + G++ +CGG LV +VLTAAHC+ + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E T QV V PHP Y+ L N D+MLL+L+ A++TD V ++L Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETLAN-----------DIMLLKLTRKADITDKVSPINL 109 Query: 142 PTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCA 199 P E G C +GWG + + KLQ VDL V S + C + +CA Sbjct: 110 PRSLAEVKPGMMCSVAGWGRLG-VNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICA 168 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G + K++ SGDSGGPLVCNGV QGI S+G P+ +YT++ + WI T+ Sbjct: 169 GDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGRNDGTTPD---VYTRISSFLSWIHSTM 223 >1OP0-A nrPDB Length = 234 Score = 147 bits (372), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 82/241 (34%), Positives = 129/241 (53%), Gaps = 19/241 (7%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC+ + + V + CGG L++P+WV+TAAHC + LG HS Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSK---- 56 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSH----DLMLLRLSEPAELTDAVKVMD 140 +V +P K +F+ P +++ D+ML++L +P + + + Sbjct: 57 ---KVLNEDEQTRNP-------KEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS 106 Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKF-MLCA 199 LP+ P++G+ C GWGSI P + P C +++++ + VC +P+ + ++ LCA Sbjct: 107 LPSSPPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCA 166 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 G GGK TC GDSGGPL+CNG QGI S+G+ PC +P +YT V Y WI+ I Sbjct: 167 GIVQGGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAG 226 Query: 260 N 260 N Sbjct: 227 N 227 >1BQY-A nrPDB Length = 234 Score = 146 bits (369), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 82/237 (34%), Positives = 121/237 (51%), Gaps = 11/237 (4%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 + GG EC + V++ + +CGG L++ WV+TAAHC N +L G HS Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q F P NR + D+ D+ML++L ++ + + LP+ Sbjct: 61 EDEQTRDPKEKFFCP--------NR--KKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSS 110 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP-QKVTKFMLCAGRWT 203 P++G+ C GWG P + + P C +++++ + VC + ++V LCAG Sbjct: 111 PPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQ 170 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GG+ TC DSGGPL+CNG+ QGI SWG PC P P +YTKV Y WIK I N Sbjct: 171 GGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >1MZD-A nrPDB Length = 240 Score = 145 bits (366), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 89/247 (36%), Positives = 132/247 (53%), Gaps = 25/247 (10%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----IRNKS-VILLGRH 78 I+GG E HS+P+ + G VCGGVL+ PQWVLTAAHC + +S ++LG H Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLR-PGDDSSHDLMLLRLSEPAELTDAVK 137 SL E + Q ++ P F R D S+D+ML++L A+L VK Sbjct: 62 SLSKNEASKQTLEIKKFIP------------FSRVTSDPQSNDIMLVKLQTAAKLNKHVK 109 Query: 138 VMDLPTQEPAL-GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-AQVHPQK---V 192 ++ + ++ GT C +GWG+ +P+ L+ V + V+S +C +Q + + Sbjct: 110 MLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFI 169 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV-HYRK 251 TK M+CAG G K +C GD+GGPL+C GV I S G E C + +P +YT + Y+ Sbjct: 170 TKDMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQT 228 Query: 252 WIKDTIV 258 WIK +V Sbjct: 229 WIKSNLV 235 >3S9B-A nrPDB Length = 234 Score = 144 bits (363), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 122/246 (49%), Gaps = 29/246 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAV--CGGVLVHPQWVLTAAHCIRNKSVILLGRHSL-F 81 +VGG EC + P+ V + + + C G L++ +WVLTAAHC R I LG HS Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 82 HPEDT------GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 ED G+ F ++ FP+ L D+ML+RL P + Sbjct: 61 RNEDEQIRVPRGKYFCLNTKFPNGL-----------------DKDIMLIRLRRPVTYSTH 103 Query: 136 VKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP-QKVTK 194 + + LP++ +G+ C GWG I + P C ++ ++ + C ++P Sbjct: 104 IAPVSLPSRSRGVGSRCRIMGWGKISTTTY--PDVPHCTNIFIVKHKWCEPLYPWVPADS 161 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254 LCAG GG+ TC GDSGGPL+CNG + GI + GSEPC +P++YTKV Y WI+ Sbjct: 162 RTLCAGILKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQ 221 Query: 255 DTIVAN 260 I N Sbjct: 222 SIIAGN 227 >5LPF-A nrPDB Length = 234 Score = 143 bits (360), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 85/233 (36%), Positives = 115/233 (49%), Gaps = 5/233 (2%) Query: 28 GWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTG 87 G C + SQPWQV + + C GVLV WVLTAAHC +G L + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGE- 65 Query: 88 QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPA 147 Q+ + + S HP Y + + P HDLMLL+L+ P L V+ + LP + Sbjct: 66 QLRRTTRSVVHPKYHQG---SGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 148 LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKS 207 G C +GWG+ K L C + ++S C +P VT M+CAG G+ Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQD 181 Query: 208 TCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 C DSGGPLVC+ LQGI SWG PC + P++YT++ Y WI I +N Sbjct: 182 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >3S69-A nrPDB Length = 234 Score = 141 bits (356), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 82/241 (34%), Positives = 124/241 (51%), Gaps = 19/241 (7%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC + V + C G L++ +WVLTAAHC + LG HS Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHS----- 55 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSH----DLMLLRLSEPAELTDAVKVMD 140 +V +P K +F+ P + D+ML++L ++ + + Sbjct: 56 --KKVLNEDEQTRNP-------KEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLS 106 Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKF-MLCA 199 LP+ P++G+ C+ GWGSI P + P C ++++ + VC +P+ +T++ LCA Sbjct: 107 LPSSPPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCA 166 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 G GGK TC GDSGGPL+CNG QGI S+G+ PC +P +YTKV Y WI+ I Sbjct: 167 GILEGGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAG 226 Query: 260 N 260 N Sbjct: 227 N 227 >1ORF-A nrPDB Length = 234 Score = 141 bits (355), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 84/227 (37%), Positives = 123/227 (54%), Gaps = 20/227 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK-SVILLGRHSLFHP 83 I+GG E HS+P+ VL++ + +C G L+ WVLTAAHC NK S ++LG HS+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 E T Q+ V FP+P YD + R GD L LL+L+E A++ V ++ LP Sbjct: 61 EPTKQIMLVKKEFPYPCYDPAT------REGD-----LKLLQLTEKAKINKYVTILHLPK 109 Query: 144 QEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK----VTKFML 197 + + GT C +GWG + L+ V++ +I VC + + M+ Sbjct: 110 KGDDVKPGTMCQVAGWGRTHNSASWS-DTLREVEITIIDRKVCNDRNHYNFNPVIGMNMV 168 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSE-PCALPERPSLY 243 CAG GG+ +C+GDSG PL+C GV +G+TS+G E C P P +Y Sbjct: 169 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVY 215 >1NN6-A nrPDB Length = 228 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 91/244 (37%), Positives = 121/244 (49%), Gaps = 26/244 (10%) Query: 25 IVGGWECEKHSQPWQV---LVASRG-RAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG EC+ HS+P+ +V S G CGG L+ +VLTAAHC + LG H++ Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 62 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 EDT Q +V F HP Y+ S L HD+MLL+L E A LT AV + Sbjct: 63 TEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKASLTLAVGTLP 111 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLTP--KKLQCVDLHVISNDVCAQVHPQKVTKFM 196 P+Q + G C +GWG L P LQ V L ++ C+ Sbjct: 112 FPSQFNFVPPGRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQACSHFRDFD-HNLQ 167 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 LC G KS GDSGGPL+C GV QGI S+G + P+++T++ HYR WI Sbjct: 168 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDA---KPPAVFTRISHYRPWINQI 224 Query: 257 IVAN 260 + AN Sbjct: 225 LQAN 228 >2CGA-A nrPDB Length = 245 Score = 139 bits (351), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 89/247 (36%), Positives = 124/247 (50%), Gaps = 22/247 (8%) Query: 22 LSRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHC-IRNKSVILLGRHS 79 LSRIV G E S PWQV + + G CGG L++ WV+TAAHC + V++ G Sbjct: 13 LSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFD 72 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 + Q +++ F + Y+ + N D+ LL+LS A + V + Sbjct: 73 QGSSSEKIQKLKIAKVFKNSKYNSLTINN-----------DITLLKLSTAASFSQTVSAV 121 Query: 140 DLPT--QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 LP+ + A GTTC +GWG TP +LQ L ++SN C + K+ M+ Sbjct: 122 CLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMI 181 Query: 198 CAGRWTGGKSTCSGDSGGPLVC--NG--VLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 CAG G S+C GDSGGPLVC NG L GI SWGS C+ P +Y +V W+ Sbjct: 182 CAG--ASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCS-TSTPGVYARVTALVNWV 238 Query: 254 KDTIVAN 260 + T+ AN Sbjct: 239 QQTLAAN 245 >3G01-A nrPDB Length = 227 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 85/241 (35%), Positives = 126/241 (52%), Gaps = 24/241 (9%) Query: 25 IVGGWECEKHSQPW----QVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG E HS+P+ + L + CGG LV ++VLTAAHC + LG H++ Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E+T Q+ V+ + PHP Y+ DD S+D+MLL+L A+ T AV+ ++ Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNP-----------DDRSNDIMLLKLVRNAKRTRAVRPLN 109 Query: 141 LPTQEPAL--GTTCYASGWGSIEPE-EFLTPKKLQCVDLHVISNDVC-AQVHPQKVTKFM 196 LP + + G CY +GWG + P+ EF PK L V L V + VC +Q Sbjct: 110 LPRRNAHVKPGDECYVAGWGKVTPDGEF--PKTLHEVKLTVQKDQVCESQFQSSYNRANE 167 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 +C G ++ GDSGGPLVC GI S+G + P+ ++T+V+ + WIK T Sbjct: 168 ICVGDSKIKGASFRGDSGGPLVCKRAAAGIVSYGQTDGSAPQ---VFTRVLSFVSWIKKT 224 Query: 257 I 257 + Sbjct: 225 M 225 >5UGG-A nrPDB Length = 251 Score = 135 bits (339), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 92/251 (36%), Positives = 124/251 (49%), Gaps = 34/251 (13%) Query: 24 RIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLGR 77 R+VGG HS PWQV + +R G CGG L+ P+WVLTAAHC+ + ++LG Sbjct: 21 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 80 Query: 78 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 H + E Q +VS F P + D+ LL+LS PA +TD V Sbjct: 81 HQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKVI 123 Query: 138 VMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVT 193 LP+ + T C+ +GWG E + L+ L VI N VC + +V Sbjct: 124 PACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQ 181 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHY 249 LCAG GG +C GDSGGPLVC +LQG+TSWG CA P +P +Y +V + Sbjct: 182 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRF 240 Query: 250 RKWIKDTIVAN 260 WI+ + N Sbjct: 241 VTWIEGVMRNN 251 >3E0N-B nrPDB Length = 271 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 90/254 (35%), Positives = 122/254 (48%), Gaps = 32/254 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI-----RNKSVILLGRHS 79 I GG PWQV + G VCGG LV QWVL+AAHC + + LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L + +V + PHP Y L+ G S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY---------LQEG--SQGDIALLQLSRPITFSRYIRPI 109 Query: 140 DLPTQEPAL--GTTCYASGWGSIEPE-EFLTPKKLQCVDLHVISNDVCAQVH-------- 188 LP + + G C +GWG + P LTPK LQ +++ +IS + C ++ Sbjct: 110 SLPAAQASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEE 169 Query: 189 PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYT 244 P V + M+CAG GGK C GDSGGPL C G+ L GI SWG + C RP +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTIV 258 Y WI+ + Sbjct: 229 LASSYASWIQSKVT 242 >3DFJ-A nrPDB Length = 263 Score = 134 bits (337), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 90/254 (35%), Positives = 121/254 (47%), Gaps = 32/254 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI-----RNKSVILLGRHS 79 I GG PWQV + G VCGG LV QWVL+AAHC + + LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L + +V + PHP Y L+ G S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY---------LQEG--SQGDIALLQLSRPITFSRYIRPI 109 Query: 140 DLPTQEPAL--GTTCYASGWGSIEPE-EFLTPKKLQCVDLHVISNDVCAQVH-------- 188 LP + G C +GWG + P LTPK LQ +++ +IS + C ++ Sbjct: 110 SLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEE 169 Query: 189 PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYT 244 P V + M+CAG GGK C GDSGGPL C G+ L GI SWG + C RP +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTIV 258 Y WI+ + Sbjct: 229 LASSYASWIQSKVT 242 >5TJX-A nrPDB Length = 263 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 92/246 (37%), Positives = 129/246 (52%), Gaps = 28/246 (11%) Query: 23 SRIVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHC-----IRNKSVIL 74 +RIVGG E PWQV + + R +CGG L+ QWVLTAAHC +++ I Sbjct: 14 TRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 73 Query: 75 LGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTD 134 G L Q+ H Y +S + +HD+ L++L P E T+ Sbjct: 74 SGILELSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLEYTE 122 Query: 135 AVKVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-K 191 K + LP++ + T C+ +GWG E+ LQ V++ +++N+ C + + K Sbjct: 123 FQKPISLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK 181 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYTKVV 247 +T+ M+CAG GGK C GDSGGPLVC NG+ L GITSWG E CA E+P +YTKV Sbjct: 182 ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVA 240 Query: 248 HYRKWI 253 Y WI Sbjct: 241 EYMDWI 246 >5FCR-A nrPDB Length = 234 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 86/245 (35%), Positives = 125/245 (51%), Gaps = 23/245 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSV-ILLGRHS 79 I+GG E H++P+ V G VCGG L+ QWVL+AAHC+ + SV +LLG HS Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L PE + + V PHP RP D DL+L +LS+ A L V+ + Sbjct: 61 LSAPEPYKRWYDVQSVVPHP----------GSRP-DSLEDDLILFKLSQNASLGPHVRPL 109 Query: 140 DLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQKVTKF 195 L ++ + GT C +GWG + P L + + +++ C H VT Sbjct: 110 PLQYEDKEVEPGTLCDVAGWGVVT-HAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTIN 168 Query: 196 MLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255 M+CA + + TC GDSG PLVC ++G+ +WGS C ++P +YT+V YR WI++ Sbjct: 169 MMCA--ESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 Query: 256 TIVAN 260 N Sbjct: 227 ITNGN 231 >4DUR-A nrPDB Length = 791 Score = 131 bits (330), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 92/251 (36%), Positives = 124/251 (49%), Gaps = 34/251 (13%) Query: 24 RIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLGR 77 R+VGG HS PWQV + +R G CGG L+ P+WVLTAAHC+ + ++LG Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 620 Query: 78 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 H + E Q +VS F P + D+ LL+LS PA +TD V Sbjct: 621 HQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKVI 663 Query: 138 VMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVT 193 LP+ + T C+ +GWG E + L+ L VI N VC + +V Sbjct: 664 PACLPSPNYVVADRTECFITGWG--ETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQ 721 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHY 249 LCAG GG +C GDSGGPLVC +LQG+TSWG CA P +P +Y +V + Sbjct: 722 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRF 780 Query: 250 RKWIKDTIVAN 260 WI+ + N Sbjct: 781 VTWIEGVMRNN 791 >1FI8-A nrPDB Length = 228 Score = 130 bits (327), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 82/240 (34%), Positives = 119/240 (49%), Gaps = 22/240 (9%) Query: 25 IVGGWECEKHSQPW----QVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG E + HS+P+ Q++ G CGG L+ +VLTAAHC +K + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E Q+ V PHP Y+ + N D+MLL+L A+ + AVK ++ Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISN-----------DIMLLKLKSKAKRSSAVKPLN 109 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM-L 197 LP + + G CY +GWG + P + LQ V+L V + C K + Sbjct: 110 LPRRNVKVKPGDVCYVAGWGKLGPMGKYS-DTLQEVELTVQEDQKCESYLKNYFDKANEI 168 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 CAG +++ GDSGGPLVC V GI S+G + P +TKV + WIK T+ Sbjct: 169 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 225 >2RDL-A nrPDB Length = 226 Score = 129 bits (323), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 81/249 (32%), Positives = 120/249 (48%), Gaps = 36/249 (14%) Query: 25 IVGGWECEKHSQPW----QVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG EC H++P+ +++ + C G L+ +V+TAAHC +LLG H+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 EDT Q +V FPHP YD L+ N D+MLL+L E A LT V + Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLN-----------DIMLLKLKEKANLTLGVGTLP 109 Query: 141 LPTQEPAL--GTTCYASGWGSIE----PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 194 + + ++ G C A GWG P + L K++ +D + PQ Sbjct: 110 ISAKSNSIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQ---- 165 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSW---GSEPCALPERPSLYTKVVHYRK 251 LC G ++ GDSGGPL+C G+ QGI S+ ++P PS++T++ HYR Sbjct: 166 --LCVGNPKKIRNVYKGDSGGPLLCAGIAQGIASYVLRNAKP------PSVFTRISHYRP 217 Query: 252 WIKDTIVAN 260 WI + N Sbjct: 218 WINKILREN 226 >3RP2-A nrPDB Length = 224 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 85/239 (35%), Positives = 123/239 (51%), Gaps = 22/239 (9%) Query: 25 IVGGWECEKHSQPWQV---LVASRG-RAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG E HS+P+ +V +G R +CGG L+ Q+VLTAAHC + ++LG H + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E T Q +V H Y+ + HD+MLL+L + ELT AV V+ Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSV-----------PNLHDIMLLKLEKKVELTPAVNVVP 109 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 198 LP+ + G C+A+GWG + T L+ V+L ++ C + KF +C Sbjct: 110 LPSPSDFIHPGAMCWAAGWGKTGVRD-PTSYTLREVELRIMDEKACVDYRYYEY-KFQVC 167 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G T ++ GDSGGPL+C GV GI S+G P A P P+++T+V Y WI I Sbjct: 168 VGSPTTLRAAFMGDSGGPLLCAGVAHGIVSYG-HPDAKP--PAIFTRVSTYVPWINAVI 223 >1AZZ-A nrPDB Length = 226 Score = 127 bits (320), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 116/232 (50%), Gaps = 15/232 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVI--LLGRHSLFH 82 IVGG E +S P Q + CGG L+ P+W+LTAAHC+ + +LG H++ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E T Q + H Y+ ++ N D+ ++RL P LT A+ + LP Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVISN-----------DIAVIRLPVPVTLTAAIATVGLP 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 + + +GT +GWG L+ VD+ ++SN C V+ VT +C Sbjct: 110 STDVGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNICIDS- 167 Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254 TGGK TC+GDSGGPL NG+ GITS+G+ P +T+V ++ WI+ Sbjct: 168 TGGKGTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >3T2N-A nrPDB Length = 372 Score = 127 bits (319), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 98/272 (36%), Positives = 132/272 (48%), Gaps = 33/272 (12%) Query: 7 FLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC 66 FL G L + RIVGG + PWQV + G +CGG L+ WVLTAAHC Sbjct: 100 FLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC 159 Query: 67 IRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPL--------YDMSLLKNRFLRPG-DDS 117 ++ + L R +F G V Q S PH L Y L F P +++ Sbjct: 160 FPERNRV-LSRWRVF----AGAVAQAS---PHGLQLGVQAVVYHGGYLP--FRDPNSEEN 209 Query: 118 SHDLMLLRLSEPAELTDAVKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVD 175 S+D+ L+ LS P LT+ ++ + LP AL G C +GWG+ + LQ Sbjct: 210 SNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEAR 268 Query: 176 LHVISNDVC--AQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQ--------G 225 + +ISNDVC A + ++ M CAG GG C GDSGGP VC + G Sbjct: 269 VPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCG 328 Query: 226 ITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 I SWG+ CAL ++P +YTKV +R+WI I Sbjct: 329 IVSWGTG-CALAQKPGVYTKVSDFREWIFQAI 359 >6I44-A nrPDB Length = 627 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 89/246 (36%), Positives = 128/246 (52%), Gaps = 28/246 (11%) Query: 23 SRIVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHC-----IRNKSVIL 74 +RIVGG + PWQV + + R +CGG L+ QWVLTAAHC +++ I Sbjct: 378 TRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 437 Query: 75 LGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTD 134 G L Q+ H Y +S + +HD+ L++L P + T+ Sbjct: 438 SGILQLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLQYTE 486 Query: 135 AVKVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-K 191 K + LP++ + T C+ +GWG E LQ V++ +++N+ C + + K Sbjct: 487 FQKPICLPSKGDTSTIYTNCWVTGWG-FSAEAGEIQNILQKVNIPLVTNEECQKRYQDYK 545 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYTKVV 247 +T+ M+CAG GGK C GD+GGPLVC NG+ L GITSWG E CA E+P +YTKV Sbjct: 546 ITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTKVA 604 Query: 248 HYRKWI 253 Y WI Sbjct: 605 EYMDWI 610 >1FUJ-A nrPDB Length = 221 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 82/246 (33%), Positives = 124/246 (50%), Gaps = 39/246 (15%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA---VCGGVLVHPQWVLTAAHCIRNKSV----ILLGR 77 IVGG E + HS+P+ + RG CGG L+HP +VLTAAHC+R+ ++LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 78 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 H++ E T Q F V+ F + YD ++ +D++L++LS PA L+ +V Sbjct: 61 HNVRTQEPTQQHFSVAQVFLNN-YD-----------AENKLNDILLIQLSSPANLSASVA 108 Query: 138 VMDLPTQEPAL--GTTCYASGWGSI----EPEEFLTPKKLQCVDLHVISNDVCAQVHPQK 191 + LP Q+ + GT C A GWG + P + L + V +++C V +K Sbjct: 109 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRK 168 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 251 C GDSGGPL+C+G++QGI S+ CA P +T+V Y Sbjct: 169 A--------------GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 214 Query: 252 WIKDTI 257 WI+ T+ Sbjct: 215 WIRSTL 220 >1BRU-P nrPDB Length = 241 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 89/252 (35%), Positives = 126/252 (50%), Gaps = 27/252 (10%) Query: 25 IVGGWECEKHSQPWQVLV----ASRGRAVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 78 +VGG + +S PWQV + + + R CGG LV WVLTAAHCI + ++LGRH Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 SL E +VS H ++ + L N +D+ LL+L+ P LTD +++ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSN---------GNDIALLKLASPVSLTDKIQL 111 Query: 139 MDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVTK 194 LP L CY +GWG ++ +P LQ L V+ C++ V Sbjct: 112 GCLPAAGTILPNNYVCYVTGWGRLQTNG-ASPDILQQGQLLVVDYATCSKPGWWGSTVKT 170 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNGV-----LQGITSWGSE-PCALPERPSLYTKVVH 248 M+CAG G S+C+GDSGGPL C G + GI S+GS C +PS++T+V + Sbjct: 171 NMICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSN 229 Query: 249 YRKWIKDTIVAN 260 Y WI I N Sbjct: 230 YIDWINSVIANN 241 >5XRF-A nrPDB Length = 242 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 76/239 (31%), Positives = 122/239 (51%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPW-QVLVASRGRAV-CGGVLVHPQWVLTAAHCIRNKSVILLGRHSL-F 81 ++GG EC+ + + SR C G L+H +WVL AAHC + I LG H+ Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 +D + + + + D L K D++LL+L++P + + + L Sbjct: 67 QFDDEQRRYAIEEHYYRC--DEKLTK---------WEKDVVLLKLNKPVSNSTHIAPLSL 115 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVTKFMLCAG 200 P+ P++G+ C GWG + + + P C ++++++ C +P T +LCAG Sbjct: 116 PSSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAG 175 Query: 201 RWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 GG TC+ DSGGPL+C+G QGI +G PCA P +P LYT+V +Y WI++ I Sbjct: 176 VLEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAG 234 >3TK9-A nrPDB Length = 226 Score = 124 bits (312), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 83/239 (34%), Positives = 120/239 (50%), Gaps = 22/239 (9%) Query: 25 IVGGWECEKHSQPWQVLVA---SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E + HS+P+ V + R CGG+LV +VLTAAHC + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E T Q V PHP Y+ + S+++MLL+L A+ T AV+ + L Sbjct: 61 EQERTQQFIPVKRPIPHPAYN-----------PKNFSNNIMLLQLERKAKWTTAVRPLRL 109 Query: 142 PTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV-HPQKVTKFMLC 198 P+ + + G C +GWG + T LQ V L V + C ++ H +C Sbjct: 110 PSSKAQVKPGQLCSVAGWGYVSMSTLAT--TLQEVLLTVQKDCQCERLFHGNYSRATEIC 167 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G ++ GDSGGPLVC V QGI S+G++ P P +Y KV H+ WIK T+ Sbjct: 168 VGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK-GTP--PGVYIKVSHFLPWIKRTM 223 >1X7A-C nrPDB Length = 235 Score = 123 bits (309), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 83/242 (34%), Positives = 119/242 (49%), Gaps = 23/242 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR--NKSVILLGRHSLFH 82 IVGG + PWQVL+ + A CGG +++ +WV+TAAHCI K ++ G ++ Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E T Q V + PH Y+ ++ N++ SHD+ LL L EP L V + + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATV--NKY-------SHDIALLELDEPLTLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 +E G+ Y SGWG + + LQ + + ++ C + + M Sbjct: 112 DKEYTNIFLKFGSG-YVSGWGRV-FNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMF 169 Query: 198 CAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 CAG GGK +C GDSGGP V L GI SWG E CA+ + +YTKV Y WI Sbjct: 170 CAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >1P57-B nrPDB Length = 255 Score = 123 bits (309), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 93/254 (36%), Positives = 126/254 (49%), Gaps = 33/254 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG + PWQV + G +CGG L+ WVLTAAHC ++ + L R +F Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRV-LSRWRVF--- 56 Query: 85 DTGQVFQVSHSFPHPL--------YDMSLLKNRFLRPG-DDSSHDLMLLRLSEPAELTDA 135 G V Q S PH L Y L F P +++S+D+ L+ LS P LT+ Sbjct: 57 -AGAVAQAS---PHGLQLGVQAVVYHGGYLP--FRDPNSEENSNDIALVHLSSPLPLTEY 110 Query: 136 VKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC--AQVHPQK 191 ++ + LP AL G C +GWG+ + LQ + +ISNDVC A + + Sbjct: 111 IQPVCLPAAGQALVDGKICTVTGWGNTQ-YYGQQAGVLQEARVPIISNDVCNGADFYGNQ 169 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQ--------GITSWGSEPCALPERPSLY 243 + M CAG GG C GDSGGP VC + GI SWG+ CAL ++P +Y Sbjct: 170 IKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG-CALAQKPGVY 228 Query: 244 TKVVHYRKWIKDTI 257 TKV +R+WI I Sbjct: 229 TKVSDFREWIFQAI 242 >2F83-A nrPDB Length = 625 Score = 123 bits (308), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 88/254 (34%), Positives = 128/254 (50%), Gaps = 28/254 (11%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHC---IRNKSVIL 74 I RIVGG + PWQV + + R +CGG ++ QW+LTAAHC + + ++ Sbjct: 384 IKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILR 443 Query: 75 LGRHSLFHPE--DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 + L E + F V H Y M+ +S +D+ LL+L Sbjct: 444 VYSGILNQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVNY 492 Query: 133 TDAVKVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP- 189 TD+ + + LP++ + T C+ +GWG + + + LQ + +++N+ C + + Sbjct: 493 TDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKI-QNTLQKAKIPLVTNEECQKRYRG 551 Query: 190 QKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYTK 245 K+T M+CAG GGK C GDSGGPL C N V L GITSWG E CA ERP +YT Sbjct: 552 HKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTN 610 Query: 246 VVHYRKWIKDTIVA 259 VV Y WI + A Sbjct: 611 VVEYVDWILEKTQA 624 >4MPW-A nrPDB Length = 245 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 91/261 (34%), Positives = 126/261 (48%), Gaps = 40/261 (15%) Query: 25 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCIRNKSVILLG----- 76 IVGG E + PWQV + G CGG L+HPQWVLTAAHC+ L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 R + +D Q+ VS HP + + + D+ LL L EP +++ V Sbjct: 61 REQHLYYQD--QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVKVSSHV 107 Query: 137 KVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPK-KLQCVDLHVISNDVC-AQVH---- 188 + LP G C+ +GWG ++ +E L P L+ V + ++ N +C A+ H Sbjct: 108 HTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 167 Query: 189 ----PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NG--VLQGITSWGSEPCALPERP 240 + V MLCAG + +C GDSGGPLVC NG + G+ SWG E CA P RP Sbjct: 168 TGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNRP 224 Query: 241 SLYTKVVHYRKWIKDTIVANP 261 +YT+V +Y WI + P Sbjct: 225 GIYTRVTYYLDWIHHYVPKKP 245 >1LTO-A nrPDB Length = 245 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 90/262 (34%), Positives = 128/262 (48%), Gaps = 42/262 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA---VCGGVLVHPQWVLTAAHC----IRNKSV--ILL 75 IVGG E + PWQV + R R CGG L+HPQWVLTAAHC +++ + + L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 L++ + Q+ VS HP + + + D+ LL L EP ++ Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYII-----------QTGADIALLELEEPVNISSR 106 Query: 136 VKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPK-KLQCVDLHVISNDVC-AQVHPQK 191 V + LP G C+ +GWG ++ +E L P L+ V + ++ N +C A+ H Sbjct: 107 VHTVMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGA 166 Query: 192 VT--------KFMLCAGRWTGGKSTCSGDSGGPLVC--NG--VLQGITSWGSEPCALPER 239 T MLCAG + +C GDSGGPLVC NG + G+ SW E CA P R Sbjct: 167 YTGDDVRIIRDDMLCAG--NSQRDSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNR 223 Query: 240 PSLYTKVVHYRKWIKDTIVANP 261 P +YT+V +Y WI + P Sbjct: 224 PGIYTRVTYYLDWIHHYVPKKP 245 >1SC8-U nrPDB Length = 262 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 124/253 (49%), Gaps = 32/253 (12%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRA-----VCGGVLVHPQWVLTAAHCI-----RNKSVI 73 +I+GG +QPW + R R VCGG L+ P WV++A HC + ++ Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 74 LLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEP---- 129 LGR L F+V + H Y L + +D+ LL++ Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHH---------NDIALLKIRSKEGRC 125 Query: 130 AELTDAVKVMDLPT--QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV 187 A+ + ++ + LP+ +P GT+C +G+G ++L P++L+ + +IS+ C Q Sbjct: 126 AQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQP 185 Query: 188 H--PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPS 241 H +VT MLCA +C GDSGGPLVC+ L GI SWG CAL ++P Sbjct: 186 HYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWG-RGCALKDKPG 244 Query: 242 LYTKVVHYRKWIK 254 +YT+V H+ WI+ Sbjct: 245 VYTRVSHFLPWIR 257 >3LC3-A nrPDB Length = 235 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 79/242 (32%), Positives = 121/242 (50%), Gaps = 23/242 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRHSLFH 82 +VGG + + PWQV++ + A CGG +V+ +W++TAAHC+ K ++ G H++ Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E T Q V PH Y+ ++ N++ +HD+ LL L EP L V + + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAI--NKY-------NHDIALLELDEPLVLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 +E G+ Y SGWG + + + LQ + + ++ C + + M Sbjct: 112 DKEYTNIFLKFGSG-YVSGWGRV-FHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMF 169 Query: 198 CAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 CAG GG+ +C GDSGGP V L GI SWG E CA+ + +YTKV Y WI Sbjct: 170 CAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAMKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >4Q7Y-A nrPDB Length = 250 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 82/241 (34%), Positives = 117/241 (48%), Gaps = 20/241 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV----ILLGRHSL 80 I+GG E HS+P+ V G+ CGG L+ +WV++AAHC ++ + ++LG H L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E T QVF + HP Y N D+ LLRL+ A L AV ++ Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHAN-----------DICLLRLNGSAVLGPAVGLLR 109 Query: 141 LPTQE---PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 LP + P GT C +GWG + E L P ++ + V+ DVC +T ML Sbjct: 110 LPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLTML 168 Query: 198 CAGRW-TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 C + + CS DSGGPLVC G+ S+ C P+ P +YT+V + WI D Sbjct: 169 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 228 Query: 257 I 257 + Sbjct: 229 V 229 >6AOD-C nrPDB Length = 245 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 85/250 (34%), Positives = 127/250 (50%), Gaps = 28/250 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHC---IRNKSVILLGRH 78 IVGG + PWQV + + R +CGG ++ QW+LTAAHC + + ++ + Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 79 SLFHPE--DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 L E + F V H Y M+ +S +D+ LL+L + TD+ Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVQYTDSQ 109 Query: 137 KVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP-QKVT 193 + + LP++ + T C+ +GWG + + + LQ + +++N+ C + + K+T Sbjct: 110 RPISLPSKGDRNVIYTDCWVTGWGYRKLRDKI-QNTLQKAKIPLVTNEECQKRYRGHKIT 168 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYTKVVHY 249 M+CAG GGK C GD+GGPL C N V L GITSWG E CA ERP +YT VV Y Sbjct: 169 HKMICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTNVVEY 227 Query: 250 RKWIKDTIVA 259 WI + A Sbjct: 228 VDWILEKTQA 237 >4DGJ-A nrPDB Length = 235 Score = 119 bits (299), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 31/246 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV------ILLGRH 78 IVGG + ++ + PW V + R +CG LV W+++AAHC+ +++ +LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 79 ---SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 +L P+ + L D ++ + R D +D+ ++ L TD Sbjct: 61 MKSNLTSPQTVPR-----------LIDEIVINPHYNRRRKD--NDIAMMHLEFKVNYTDY 107 Query: 136 VKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KV 192 ++ + LP + G C +GWG++ + T LQ D+ ++SN+ C Q P+ + Sbjct: 108 IQPISLPEENQVFPPGRNCSIAGWGTV-VYQGTTADILQEADVPLLSNERCQQQMPEYNI 166 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCNG----VLQGITSWGSEPCALPERPSLYTKVVH 248 T+ M+CAG GG +C GDSGGPL+C L G+TS+G E CALP RP +Y +V Sbjct: 167 TENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYE-CALPNRPGVYARVSR 225 Query: 249 YRKWIK 254 + +WI+ Sbjct: 226 FTEWIQ 231 >2ZKS-A nrPDB Length = 240 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 120/239 (50%), Gaps = 23/239 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV---ILLGRHSLF 81 I+GG E HS+P+ + G +CGGVLVHP+WVLTAAHC+ + ++LG H+L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 P G F + + HP Y +P +DL LL+L + + ++ + L Sbjct: 61 SP---GLTFHIKAAIQHPRY----------KPVPALENDLALLQLDGKVKPSRTIRPLAL 107 Query: 142 PTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVTKFML 197 P++ A GT C +GWG L+ + L+ +DL V+ +C ++ M+ Sbjct: 108 PSKRQVVAAGTRCSMAGWGLTHQGGRLS-RVLRELDLQVLDTRMCNNSRFWNGSLSPSMV 166 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNG--VLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254 C + ++ C GDSGGPLVC VL G+ S+ S C +P + T V Y WI+ Sbjct: 167 CLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIR 225 >4Z6A-H nrPDB Length = 249 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 84/251 (33%), Positives = 125/251 (49%), Gaps = 27/251 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC---IRN--KSVILLGRHS 79 IVGG C K PWQVL+ G +CGG L++ WV++AAHC I+N + +LG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L + Q +V+ Y PG ++HD+ LLRL +P LTD V + Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTY----------VPG-TTNHDIALLRLHQPVVLTDHVVPL 109 Query: 140 DLPTQEPALGTTCY-----ASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 194 LP + + T + SGWG + + T +L +++ + C +P K+T+ Sbjct: 110 CLPERTFSERTLAFVRFSLVSGWGQLL-DRGATALELMVLNVPRLMTQDCEASYPGKITE 168 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNG----VLQGITSWGSEPCALPERPSLYTKVVHYR 250 +M CAG G K +C GDSGGP + L GI SWG + CA +YT+V Y Sbjct: 169 YMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG-QGCATVGHFGVYTRVSQYI 227 Query: 251 KWIKDTIVANP 261 +W++ + + P Sbjct: 228 EWLQKLMRSEP 238 >1IAU-A nrPDB Length = 227 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 118/239 (49%), Gaps = 21/239 (8%) Query: 25 IVGGWECEKHSQPWQVLVA---SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E + HS+P+ + + CGG L+ +VLTAAHC + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E T Q V PHP Y+ + S+D+MLL+L A+ T AV+ + L Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPK-----------NFSNDIMLLQLERKAKRTRAVQPLRL 109 Query: 142 PTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-AQVHPQKVTKFMLC 198 P+ + + G TC +GWG P + LQ V + V + C + + + LC Sbjct: 110 PSNKAQVKPGQTCSVAGWGQTAPLGKHS-HTLQEVKMTVQEDRKCESDLRHYYDSTIELC 168 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G K++ GDSGGPLVCN V QGI S+G +P P TKV + WIK T+ Sbjct: 169 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKTM 224 >1YC0-A nrPDB Length = 283 Score = 117 bits (293), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 81/255 (31%), Positives = 119/255 (46%), Gaps = 29/255 (11%) Query: 20 LILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI-----RNKSVIL 74 + RI+GG S PW + G + C G LVH WV++AAHC R+ ++ Sbjct: 31 FLRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVV 89 Query: 75 LGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTD 134 LG+H D Q F + P+ LY + P D HDL+L+RL + + Sbjct: 90 LGQHFFNRTTDVTQTFGIEKYIPYTLYSV-------FNPSD---HDLVLIRLKKKGDRCA 139 Query: 135 AVKVMDLPTQEPALGTT------CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--Q 186 P P G+T C +GWG ++ L+ + ++++ C+ + Sbjct: 140 TRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPE 199 Query: 187 VHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSL 242 V+ ++ MLCAG + C GDSGGPL C NGV L GI SWG + C +P + Sbjct: 200 VYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHKPGV 258 Query: 243 YTKVVHYRKWIKDTI 257 YT+V +Y WI D I Sbjct: 259 YTRVANYVDWINDRI 273 >1KYN-A nrPDB Length = 235 Score = 116 bits (291), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 75/238 (31%), Positives = 113/238 (47%), Gaps = 21/238 (8%) Query: 25 IVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E HS+P+ + + G++ CGG LV +VLTAAHC + + LG H++ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E+T Q + HP Y+ ++N D+MLL+LS V + L Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQN-----------DIMLLQLSRRVRRNRNVNPVAL 109 Query: 142 PTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCA 199 P + L GT C +GWG + L+ V L V + C ++ + +C Sbjct: 110 PRAQEGLRPGTLCTVAGWGRVSMRR--GTDTLREVQLRVQRDRQCLRIFGSYDPRRQICV 167 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G K+ GDSGGPL+CN V GI S+G PE ++T+V + WI+ T+ Sbjct: 168 GDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPE---VFTRVSSFLPWIRTTM 222 >1EKB-B nrPDB Length = 235 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 74/246 (30%), Positives = 126/246 (51%), Gaps = 31/246 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV------ILLGRH 78 IVGG + + + PW V + + VCG LV W+++AAHC+ +++ +LG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS---SHDLMLLRLSEPAELTDA 135 ++ + P + L+ + P + ++D+ ++ L TD Sbjct: 61 -------------MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDY 107 Query: 136 VKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KV 192 ++ + LP + G C +GWG++ + T LQ D+ ++SN+ C Q P+ + Sbjct: 108 IQPICLPEENQVFPPGRICSIAGWGAL-IYQGSTADVLQEADVPLLSNEKCQQQMPEYNI 166 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCNG----VLQGITSWGSEPCALPERPSLYTKVVH 248 T+ M+CAG GG +C GDSGGPL+C +L G+TS+G + CALP RP +Y +V Sbjct: 167 TENMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQ-CALPNRPGVYARVPR 225 Query: 249 YRKWIK 254 + +WI+ Sbjct: 226 FTEWIQ 231 >2R0L-A nrPDB Length = 248 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 80/250 (32%), Positives = 117/250 (46%), Gaps = 29/250 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI-----RNKSVILLGRHS 79 I+GG S PW + G + C G LVH WV++AAHC R+ ++LG+H Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 D Q F + P+ LY + P D HDL+L+RL + + Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSV-------FNPSD---HDLVLIRLKKKGDRCATRSQF 109 Query: 140 DLPTQEPALGTT------CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQK 191 P P G+T C +GWG ++ L+ + ++++ C+ +V+ Sbjct: 110 VQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD 169 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV--LQGITSWGSEPCALPERPSLYTKVV 247 ++ MLCAG + C GDSGGPL C NGV L GI SWG + C +P +YT+V Sbjct: 170 ISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHKPGVYTRVA 228 Query: 248 HYRKWIKDTI 257 +Y WI D I Sbjct: 229 NYVDWINDRI 238 >3W94-A nrPDB Length = 235 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 120/245 (48%), Gaps = 25/245 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVIL------LGRH 78 +VGG EK + PW V + RGR CG L+ W+LTAAHC+ K+ L LG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 + Q Q+ D ++ + R ++ D+ ++ L +P T+ V Sbjct: 61 A--QSSMNSQEVQIRQ------VDRIIINKNYNRRTKEA--DIAMMHLQQPVNFTEWVLP 110 Query: 139 MDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVTKF 195 + L +++ G C+ +GWG + E P LQ ++ ++ D C ++ P+ T Sbjct: 111 VCLASEDQHFPAGRRCFIAGWGR-DAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSS 169 Query: 196 MLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHYRK 251 MLCAG GG +C GDSGGPL+C L G+TS+G C PERP Y +V + Sbjct: 170 MLCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTS 228 Query: 252 WIKDT 256 WI +T Sbjct: 229 WIAET 233 >3F6U-H nrPDB Length = 240 Score = 114 bits (286), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 115/250 (46%), Gaps = 29/250 (11%) Query: 25 IVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCI--RNKSVILLGRHSLF 81 ++ G + PWQV L+ S+ + CG VL+HP WVLTAAHC+ K ++ LG + L Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLR 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E + F HP Y S N D+ LL L++PA L+ + + L Sbjct: 61 RWEKWELDLDIKEVFVHPNYSKSTTDN-----------DIALLHLAQPATLSQTIVPICL 109 Query: 142 PTQEPA------LGTTCYASGWGSIEPEEFLTPKK----LQCVDLHVISNDVCAQVHPQK 191 P A G +GWG E + L + + V+ ++ C++V Sbjct: 110 PDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNM 169 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG----VLQGITSWGSEPCALPERPSLYTKVV 247 V++ MLCAG + C GDSGGP+V + L G+ SWG E C L +YTKV Sbjct: 170 VSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVS 228 Query: 248 HYRKWIKDTI 257 Y WI I Sbjct: 229 RYLDWIHGHI 238 >1AE5-A nrPDB Length = 225 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 80/244 (32%), Positives = 119/244 (48%), Gaps = 31/244 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRHSL 80 IVGG + P+ + ++GR CGG L+H ++V+TAA C +++ S ++LG + L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 81 FHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 E + Q F +S S YD + +DLMLL+L A LT +V ++ Sbjct: 61 RRRERQSRQTFSIS-SMSENGYDP-----------QQNLNDLMLLQLDREANLTSSVTIL 108 Query: 140 DLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 LP Q + GT C +GWGS L+ + + V++ V D C P V Sbjct: 109 PLPLQNATVEAGTRCQVAGWGSQRSGGRLS-RFPRFVNVTVTPEDQC---RPNNV----- 159 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 C G T C+GD G PLVC G+ G+ S+ PC P +T+V +R WI D + Sbjct: 160 CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWI-DGV 216 Query: 258 VANP 261 + NP Sbjct: 217 LNNP 220 >4H4F-A nrPDB Length = 249 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 129/250 (51%), Gaps = 30/250 (12%) Query: 25 IVGGWECEKHSQPWQV----LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 78 +VGG + HS PWQ+ L R CGG L+ +VLTAAHCI N + +G++ Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 SLFHPEDTGQVF-QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 +L ++ G +F V H ++ LL+N D+ L++L+E EL+D ++ Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-----------DIALIKLAEHVELSDTIQ 109 Query: 138 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVT 193 V LP ++ L CY +GWG + + K Q + V+ + C+++ +V Sbjct: 110 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ-PVVDHATCSRIDWWGFRVK 168 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVC---NGVLQ--GITSWGSEP-CALPERPSLYTKVV 247 K M+CAG G S C+GDSGGPL C NG + GI S+GS C ++P +YT+V Sbjct: 169 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 227 Query: 248 HYRKWIKDTI 257 Y WI + + Sbjct: 228 AYIDWINEKM 237 >5GVT-A nrPDB Length = 250 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 82/244 (33%), Positives = 115/244 (47%), Gaps = 28/244 (11%) Query: 25 IVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHCIRNKSV-----ILLG 76 IVGG PWQV + + +CGG ++ QWVLTAAHC I G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 SL ++ H Y +S + ++D+ L++L P T+ Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVS-----------EGNYDIALIKLQTPLNYTEFQ 109 Query: 137 KVMDLPTQEPA--LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKV-T 193 K + LP++ + T C+ +GWG + E+ T LQ + ++ N+ C + + V Sbjct: 110 KPISLPSKADTNTIYTNCWVTGWGYTK-EQGETQNILQKATIPLVPNEECQKKYRDYVIN 168 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVCNGV----LQGITSWGSEPCALPERPSLYTKVVHY 249 K M+CAG GG C GDSGGPLVC L GITSWG E CA ++P +YTKV Y Sbjct: 169 KQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWG-EGCARKDQPGVYTKVSEY 227 Query: 250 RKWI 253 WI Sbjct: 228 MDWI 231 >2V35-A nrPDB Length = 240 Score = 110 bits (276), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 123/253 (48%), Gaps = 30/253 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA----VCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 78 +VGG E +++S P Q+ + R + CGG L+ WV+TAAHC+ + +++G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDD--SSHDLMLLRLSEPAELTDAV 136 +L + T Q V HP ++ DD + +D+ LLRL++ L V Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNT-----------DDVAAGYDIALLRLAQSVTLNSYV 109 Query: 137 KVMDLPTQEPALGTT--CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKV 192 ++ LP L CY +GWG L + LQ L + +C+ V Sbjct: 110 QLGVLPRAGTILANNSPCYITGWGLTRTNGQL-AQTLQQAYLPTVDYAICSSSSYWGSTV 168 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVC--NG--VLQGITSWGSE-PCALPERPSLYTKVV 247 M+CAG G +S C GDSGGPL C NG + G+TS+ S C + +P+++T+V Sbjct: 169 KNSMVCAGG-DGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVS 227 Query: 248 HYRKWIKDTIVAN 260 Y WI + I +N Sbjct: 228 AYISWINNVIASN 240 >4IGD-A nrPDB Length = 406 Score = 110 bits (275), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 75/262 (28%), Positives = 123/262 (46%), Gaps = 42/262 (16%) Query: 21 ILSRIVGGWECEKHSQPWQVLVAS-RGRAVCGGVLVHPQWVLTAAHCI-----------R 68 ++++I G +K + PW +++ G+ CGG L+ W++TAAHC+ R Sbjct: 152 LMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLR 211 Query: 69 NKSV-------ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDL 121 + + I+LG+H ++ Q V H+ HP YD + +N D+ Sbjct: 212 DSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFEN-----------DV 260 Query: 122 MLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISN 181 L+ L E L V + LP G SGWG + F P+ L +++ ++ + Sbjct: 261 ALVELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDH 318 Query: 182 DVCAQVH---PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG------VLQGITSWGSE 232 C + + +KVT+ M+CAG GGK C+GDSGGP+V L G SWG + Sbjct: 319 STCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD 378 Query: 233 PCALPERPSLYTKVVHYRKWIK 254 C +R +Y+ + H + WI+ Sbjct: 379 -CGKKDRYGVYSYIHHNKDWIQ 399 >1PYT-D nrPDB Length = 251 Score = 110 bits (275), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 129/255 (50%), Gaps = 29/255 (11%) Query: 19 PLILSRIVGGWECEKHSQPWQV----LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV-- 72 P + +R+VGG + HS PWQ+ L + R CGG L+ P VLTAAHCI N Sbjct: 8 PNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYR 67 Query: 73 ILLGRHSLFHPEDTGQVF-QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + LG+++L ++ G ++ V F H ++ L++N D+ L++L+E E Sbjct: 68 VALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRN-----------DIALIKLAETVE 116 Query: 132 LTDAVKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH- 188 L D ++V LP++ L C+ +GWG + + + Q + V+ C+Q Sbjct: 117 LGDTIQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQ-PVVDYATCSQRDW 175 Query: 189 -PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQ----GITSWGSE-PCALPERPSL 242 V + M+CAG G S C+GDSGGPL C Q GI S+GS C ++P++ Sbjct: 176 WGTTVKETMVCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTV 234 Query: 243 YTKVVHYRKWIKDTI 257 +T+V Y WI + Sbjct: 235 FTRVSAYIDWINQKL 249 >5LHN-A nrPDB Length = 247 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 77/258 (29%), Positives = 123/258 (47%), Gaps = 37/258 (14%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA------VCGGVLVHPQWVLTAAHCI-----RNKSVI 73 IVGG E +QPW + + + CGG L+ P WV +AAHC + V+ Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 LLG--RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRL----S 127 LG + S ++P + F+V H Y L +D+ LL++ Sbjct: 61 YLGQSKESSYNPGEMK--FEVEQLILHEYYREDSLAYH---------NDIALLKIRTSTG 109 Query: 128 EPAELTDAVKVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185 + A+ + +++ + LP + + G+ C +G+G ++L PK L+ + ++S++ C Sbjct: 110 QCAQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCM 169 Query: 186 QVH--PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPER 239 Q H ++ MLCA +C GDSGGPL+CN L GI SWG CA + Sbjct: 170 QPHYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG-RGCAEKNK 228 Query: 240 PSLYTKVVHYRKWIKDTI 257 P +YT+V H+ WI+ I Sbjct: 229 PGVYTRVSHFLDWIQSHI 246 >4DJZ-B nrPDB Length = 251 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 119/258 (46%), Gaps = 42/258 (16%) Query: 25 IVGGWECEKHSQPWQVLVAS-RGRAVCGGVLVHPQWVLTAAHCI-----------RNKSV 72 I G +K + PW +++ G+ CGG L+ W++TAAHC+ R+ + Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 73 -------ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125 I+LG+H ++ Q V H+ HP YD + +N D+ L+ Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFEN-----------DVALVE 109 Query: 126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185 L E L V + LP G SGWG + F P+ L +++ ++ + C Sbjct: 110 LLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDHSTCQ 167 Query: 186 QVH---PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG------VLQGITSWGSEPCAL 236 + + +KVT+ M+CAG GGK C+GDSGGP+V L G SWG + C Sbjct: 168 KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD-CGK 226 Query: 237 PERPSLYTKVVHYRKWIK 254 +R +Y+ + H + WI+ Sbjct: 227 KDRYGVYSYIHHNKDWIQ 244 >4XDE-A nrPDB Length = 257 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 82/256 (32%), Positives = 117/256 (45%), Gaps = 34/256 (13%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV-----ILLGRHS 79 +VGG + + P+ + G + C G L+ P WVLTAAHC++++ ++LG+ Sbjct: 3 VVGGLVALRGAHPY-IAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE-----LTD 134 H + Q V H + + HDL LLRL E A+ L+ Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQ-----------HDLALLRLQEDADGSCALLSP 110 Query: 135 AVKVMDLPT--QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQ 190 V+ + LP+ P+ T C +GWG LQ + +S + C+ VH Sbjct: 111 YVQPVSLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS 170 Query: 191 KVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPERPSLY 243 + MLCAG GG C GDSGGPLVC LQGI SWGS C +P +Y Sbjct: 171 SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSG-CGDRNKPGVY 229 Query: 244 TKVVHYRKWIKDTIVA 259 T V +Y WI++ V+ Sbjct: 230 TDVAYYLAWIREHTVS 245 >3P8G-A nrPDB Length = 241 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 75/251 (29%), Positives = 118/251 (47%), Gaps = 32/251 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA-VCGGVLVHPQWVLTAAHCIRNKS----------VI 73 +VGG + ++ PWQV + + G+ +CG L+ P W+++AAHC + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 74 LLGRHSLFHPEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 LG H G Q ++ HP + N F +D+ LL L +PAE Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFF------NDFT-----FDYDIALLELEKPAEY 109 Query: 133 TDAVKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190 + V+ + LP G + +GWG + LQ ++ VI C + PQ Sbjct: 110 SSMVRPICLPDASHVFPAGKAIWVTGWGHTQ-YGGTGALILQKGEIRVIQQTTCENLLPQ 168 Query: 191 KVTKFMLCAGRWTGGKSTCSGDSGGPLV---CNGVL--QGITSWGSEPCALPERPSLYTK 245 ++T M+C G +GG +C GDSGGPL +G + G+ SWG + CA +P +YT+ Sbjct: 169 QITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG-DGCAQRNKPGVYTR 227 Query: 246 VVHYRKWIKDT 256 + +R WIK+ Sbjct: 228 LPLFRDWIKEN 238 >1A5I-A nrPDB Length = 265 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 81/261 (31%), Positives = 121/261 (46%), Gaps = 41/261 (15%) Query: 26 VGGWECEKHSQPWQVLVASRGRA------VCGGVLVHPQWVLTAAHCIRNKSV-----IL 74 GG + S PWQ + ++ R +CGG+L+ WVLTAAHC + + ++ Sbjct: 15 TGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVV 74 Query: 75 LGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS----EPA 130 LGR P + Q F+V H +D D ++D+ LL+L + A Sbjct: 75 LGRTYRVKPGEEEQTFKVKKYIVHKEFD-----------DDTYNNDIALLQLKSDSPQCA 123 Query: 131 ELTDAVKVMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ-- 186 + +D+V+ + LP L T C SG+G + ++L+ + + + CA Sbjct: 124 QESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKF 183 Query: 187 VHPQKVTKFMLCAGRWTGGK------STCSGDSGGPLVCNG----VLQGITSWGSEPCAL 236 + + VT MLCAG G+ C GDSGGPLVC L GI SWG C Sbjct: 184 LFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGE 242 Query: 237 PERPSLYTKVVHYRKWIKDTI 257 + P +YTKV +Y WI+D + Sbjct: 243 KDVPGVYTKVTNYLGWIRDNM 263 >1BDA-A nrPDB Length = 265 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 82/263 (31%), Positives = 119/263 (45%), Gaps = 41/263 (15%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRA------VCGGVLVHPQWVLTAAHCIRNKS-----V 72 RI GG + S PWQ + ++ R +CGG+L+ W+L+AAHC + + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 73 ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRL----SE 128 ++LGR P + Q F+V H +D D +D+ LL+L S Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFD-----------DDTYDNDIALLQLKSDSSR 121 Query: 129 PAELTDAVKVMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ 186 A+ + V+ + LP + L T C SG+G E ++L+ + + + C Sbjct: 122 CAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTS 181 Query: 187 VH--PQKVTKFMLCAGRWTGG------KSTCSGDSGGPLVC----NGVLQGITSWGSEPC 234 H + VT MLCAG G C GDSGGPLVC L GI SWG C Sbjct: 182 QHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGL-GC 240 Query: 235 ALPERPSLYTKVVHYRKWIKDTI 257 + P +YTKV +Y WI+D + Sbjct: 241 GQKDVPGVYTKVTNYLDWIRDNM 263 >2OCV-B nrPDB Length = 259 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 76/265 (28%), Positives = 115/265 (43%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV GW+ EK PWQV++ + +CG L+ +WVLTAAHCI N + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E + ++ + + HP Y+ ++ D+ LL+L +P Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWR----------ENLDRDIALLKLKKPVP 110 Query: 132 LTDAVKVMDLPTQEPAL-----GTTCYASGWGSIEPE-----EFLTPKKLQCVDLHVISN 181 +D + + LP ++ G +GWG++ + P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVER 170 Query: 182 DVCAQVHPQKVTKFMLCAG---RWTGGKSTCSGDSGGPLVCNGVLQ------GITSWGSE 232 VC ++T M CAG T C GDSGGP V GI SWG E Sbjct: 171 PVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-E 229 Query: 233 PCALPERPSLYTKVVHYRKWIKDTI 257 C + YT V + WI+ I Sbjct: 230 GCDRKGKYGFYTHVFRLKAWIQKVI 254 >2OQ5-A nrPDB Length = 232 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 75/244 (30%), Positives = 111/244 (45%), Gaps = 33/244 (13%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI---RNKSVILLGRHSLF 81 IVGG E E+ PWQ + G CG L++ W+++AAHC +N + Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 82 HPEDTGQVFQ---VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 P + + V + HP +D +D+ L LS P T+AV Sbjct: 61 KPSKMKRGLRRIIVHEKYKHPSHD----------------YDISLAELSSPVPYTNAVHR 104 Query: 139 MDLP--TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQKVTK 194 + LP + E G + +G+G+++ + + + L+ + +I C Q + +T Sbjct: 105 VCLPDASYEFQPGDVMFVTGFGALKNDGY-SQNHLRQAQVTLIDATTCNEPQAYNDAITP 163 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNGV-----LQGITSWGSEPCALPERPSLYTKVVHY 249 MLCAG G C GDSGGPLV + L GI SWG E CA P +P +YT+V Sbjct: 164 RMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTAL 222 Query: 250 RKWI 253 R WI Sbjct: 223 RDWI 226 >2XRC-A nrPDB Length = 565 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 82/251 (32%), Positives = 112/251 (44%), Gaps = 41/251 (16%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSVILLGRHS 79 RIVGG + PWQV + CGG+ + W+LTAAHC+R ++ I Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 380 Query: 80 LFHPEDTGQVFQ-VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 HP+ V + V H Y+ +N D+ L+ + + D Sbjct: 381 WIHPDLKRIVIEYVDRIIFHENYNAGTYQN-----------DIALIEMKKDGNKKDC--- 426 Query: 139 MDLPTQEPAL----------GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH 188 +LP PA TC SGWG + E + LQ ++ +ISN C++ + Sbjct: 427 -ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFY 481 Query: 189 PQKV-TKFMLCAGRWTGGKSTCSGDSGGPLVC---NGVLQ--GITSWGSEPCALPERPSL 242 + K M CAG + G C GDSGGPLVC N V G+ SWG E C PE P + Sbjct: 482 GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGV 540 Query: 243 YTKVVHYRKWI 253 YTKV +Y WI Sbjct: 541 YTKVANYFDWI 551 >5KWM-A nrPDB Length = 230 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 78/240 (32%), Positives = 109/240 (45%), Gaps = 21/240 (8%) Query: 25 IVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCIRNKS----VILLGRHS 79 IVGG + P+ V LV G+ CGG L P V+TAAHC ++ GR Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 + E G V +V++ + HP Y + D+ +L L P + +++ Sbjct: 61 MSSNE--GTVSKVTNVWVHPEYQDAA-----------KGFDVSVLTLEAPVKEA-PIELA 106 Query: 140 DLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCA 199 A T GWG+ E LQ + V S+D C Q + + M+CA Sbjct: 107 KADDAGYAPDTAATILGWGNTS-EGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCA 165 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 G GG TC GDSGGP+V N L G+TSWG E CA P +P +Y +V Y + + I A Sbjct: 166 GVPEGGVDTCQGDSGGPMVVNNKLIGVTSWG-EGCARPGKPGVYARVGAYYDVLMEQINA 224 >1PPF-E nrPDB Length = 218 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 76/239 (31%), Positives = 112/239 (46%), Gaps = 28/239 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC----IRNKSVILLGRHSL 80 IVGG H+ P+ V + RG CG L+ P +V++AAHC ++LG H+L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E T QVF V F + ++LL +D+++L+L+ A + V+V Sbjct: 61 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSATINANVQVAQ 108 Query: 141 LPTQEPALGT--TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 198 LP Q LG C A GWG + + LQ +++ V++ +C ++ L Sbjct: 109 LPAQGRRLGNGVQCLAMGWGLLGRNRGIA-SVLQELNVTVVT-SLC-----RRSNVCTLV 161 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 GR G C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 162 RGRQAG---VCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 217 >2F91-A nrPDB Length = 237 Score = 104 bits (259), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 110/250 (44%), Gaps = 29/250 (11%) Query: 25 IVGGWECEKHSQPWQVLVASR----GRAVCGGVLVHPQWVLTAAHCIRNKSV-------I 73 IVGG + P+Q+ CG + + + +TA HC+ I Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 74 LLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELT 133 + G + E + Q+ VS H +D +LL N D+ LL+LS Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDN-----------DISLLKLSGSLTFN 109 Query: 134 DAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-AQVHPQKV 192 D V + LP Q +GWG+ E TP LQ V + ++S++ C A ++ Sbjct: 110 DNVAPIALPEQGHTATGDVIVTGWGTTS-EGGNTPDVLQKVTVPLVSDEDCRADYGADEI 168 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCNGV----LQGITSWGSEPCALPERPSLYTKVVH 248 M+CAG GGK +C GDSGGPL + L GI SWG CA P P +YT+V + Sbjct: 169 LDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGY-GCARPGYPGVYTEVSY 227 Query: 249 YRKWIKDTIV 258 + WIK V Sbjct: 228 HVDWIKANAV 237 >1ELT-A nrPDB Length = 236 Score = 103 bits (258), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 118/245 (48%), Gaps = 27/245 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA----VCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 78 +VGG + +S PWQ+ + + + CGG L+ WV+TAAHC+ + ++LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 +L E Q+ V+ F H ++ + + D+ LLRL+ A L AV++ Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGY---------DIALLRLNTQASLNSAVQL 111 Query: 139 MDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH--PQKVTK 194 LP L CY +GWG L+ L+ L + + C+ V Sbjct: 112 AALPPSNQILPNNNPCYITGWGKTSTGGPLS-DSLKQAWLPSVDHATCSSSGWWGSTVKT 170 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVC--NG--VLQGITSW-GSEPCALPERPSLYTKVVHY 249 M+CAG G S C+GDSGGPL C NG + G+TS+ S C ++P+++T+V Y Sbjct: 171 TMVCAGG--GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAY 228 Query: 250 RKWIK 254 W+ Sbjct: 229 ISWMN 233 >5O32-I nrPDB Length = 244 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 112/250 (44%), Gaps = 41/250 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSVILLGRHSL 80 IVGG + PWQV + CGG+ + W+LTAAHC+R ++ I Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 81 FHPEDTGQVFQ-VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 HP+ V + V H Y+ +N D+ L+ + + D Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQN-----------DIALIEMKKDGNKKDC---- 105 Query: 140 DLPTQEPAL----------GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP 189 +LP PA TC SGWG + E + LQ ++ +ISN C++ + Sbjct: 106 ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLISN--CSKFYG 161 Query: 190 QKV-TKFMLCAGRWTGGKSTCSGDSGGPLVC---NGV--LQGITSWGSEPCALPERPSLY 243 + K M CAG + G C GDSGGPLVC N V + G+ SWG E C PE P +Y Sbjct: 162 NRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVY 220 Query: 244 TKVVHYRKWI 253 TKV +Y WI Sbjct: 221 TKVANYFDWI 230 >1FON-A nrPDB Length = 240 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 80/245 (32%), Positives = 122/245 (49%), Gaps = 30/245 (12%) Query: 34 HSQPWQVLVASRGRAV----CGGVLVHPQWVLTAAHCIRNKSV--ILLGRHSLFHPEDTG 87 +S WQV + CGG L+ P WV+TA HCI ++LG + E + Sbjct: 8 YSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRSVLEGSE 67 Query: 88 QVFQVSHS--FPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQE 145 QV ++ F HPL++ + + +D+ L++LS A+L D V++ +LP Sbjct: 68 QVIPINAGDLFVHPLWNSNCVA---------CGNDIALVKLSRSAQLGDKVQLANLPPAG 118 Query: 146 PALGTT--CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVT--KFMLCAGR 201 L CY SGWG + L P KLQ L + + C+Q +T K M+CAG Sbjct: 119 DILPNEAPCYISGWGRLYTGGPL-PDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGG 177 Query: 202 WTGGKSTCSGDSGGPLVCNGV-----LQGITSWGSE-PCALPERPSLYTKVVHYRKWIKD 255 T +S C+GDSGGPL C + G+TS+ S C ++P+++T+V + WI + Sbjct: 178 DT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDE 235 Query: 256 TIVAN 260 TI +N Sbjct: 236 TIASN 240 >1EQ9-A nrPDB Length = 222 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 82/244 (33%), Positives = 115/244 (47%), Gaps = 41/244 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLGRHS 79 IVGG + P+QV + G CG ++ VLTAAHC+ N+ + +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L ++G V+ V + + YD LL+N D+ L+ L+ P + D V+ + Sbjct: 61 L---SESGDVYDVEDAVVNKNYDDFLLRN-----------DVALVHLTNPIKFNDLVQPI 106 Query: 140 DLPTQEPALGTT-CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK------- 191 L T + L + C +GWGS TP LQ ++L VHPQK Sbjct: 107 KLSTNDEDLESNPCTLTGWGSTRLGGN-TPNALQEIEL---------IVHPQKQCERDQW 156 Query: 192 -VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYR 250 V +C G+ C GDSGGPLV NG GI S+GS PCAL E P +YT+V + Sbjct: 157 RVIDSHICT-LTKRGEGACHGDSGGPLVANGAQIGIVSFGS-PCALGE-PDVYTRVSSFV 213 Query: 251 KWIK 254 WI Sbjct: 214 SWIN 217 >1SI5-H nrPDB Length = 240 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 74/236 (31%), Positives = 107/236 (45%), Gaps = 34/236 (14%) Query: 38 WQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV----ILLGRHSLF--HPEDTGQVFQ 91 W V + R + +CGG L+ WVLTA C ++ + LG H + E QV Sbjct: 13 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 72 Query: 92 VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL--G 149 VS P DL+L++L+ PA L D V +DLP + Sbjct: 73 VSQLVYGP-----------------EGSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEK 115 Query: 150 TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVT--KFMLCAGRWTGGKS 207 T+C GWG + L+ L+++ N+ C+Q H KVT + +CAG G Sbjct: 116 TSCSVYGWGYTGLINY--DGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSG 173 Query: 208 TCSGDSGGPLVCNG----VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 C GD GGPLVC ++ G+ G CA+P RP ++ +V +Y KWI I+ Sbjct: 174 PCEGDYGGPLVCEQHKMRMVLGVIVPG-RGCAIPNRPGIFVRVAYYAKWIHKIILT 228 >1MKW-K nrPDB Length = 308 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 84/270 (31%), Positives = 122/270 (45%), Gaps = 45/270 (16%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI------RNKSV 72 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ +N +V Sbjct: 46 IEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTV 105 Query: 73 ----ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127 + +G+HS E ++ + + HP Y+ ++ D+ LL+L Sbjct: 106 DDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLK 155 Query: 128 EPAELTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPEEFLT------PKKLQCVDL 176 P EL+D + + LP ++ A G +GWG+ E + T P LQ V+L Sbjct: 156 RPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGN-RRETWTTSVAEVQPSVLQVVNL 214 Query: 177 HVISNDVCAQVHPQKVTKFMLCAGRWTG-GK--STCSGDSGGPLVCNG------VLQGIT 227 ++ VC ++T M CAG G GK C GDSGGP V GI Sbjct: 215 PLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIV 274 Query: 228 SWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 SWG E C + YT V +KWI+ I Sbjct: 275 SWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >1AKS-B nrPDB Length = 98 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 48/93 (51%), Positives = 60/93 (64%), Gaps = 1/93 (1%) Query: 168 PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGIT 227 P LQC+ V+SN C +P ++T M+C G GGK +C GDSGGP+VCNG LQGI Sbjct: 7 PSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNGQLQGIV 66 Query: 228 SWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 SWG CA +P +YTKV +Y WI+ TI AN Sbjct: 67 SWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >3K65-B nrPDB Length = 308 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 77/269 (28%), Positives = 119/269 (44%), Gaps = 43/269 (15%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------R 68 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ Sbjct: 46 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 105 Query: 69 NKSVILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127 N ++ +G+HS E + ++ + + HP Y+ ++ D+ L++L Sbjct: 106 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 155 Query: 128 EPAELTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPEEFLT-----PKKLQCVDLH 177 +P +D + + LP +E A G +GWG+++ P LQ V+L Sbjct: 156 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 215 Query: 178 VISNDVCAQVHPQKVTKFMLCAG-RWTGGK--STCSGDSGGPLVCNGVLQ------GITS 228 ++ VC ++T M CAG + GK C GD+GGP V GI S Sbjct: 216 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVS 275 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTI 257 WG E C + YT V +KWI+ I Sbjct: 276 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >3NXP-A nrPDB Length = 424 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 78/269 (28%), Positives = 119/269 (44%), Gaps = 43/269 (15%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------R 68 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ Sbjct: 162 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 221 Query: 69 NKSVILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127 N ++ +G+HS E + ++ + + HP Y+ ++ D+ L++L Sbjct: 222 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 271 Query: 128 EPAELTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPEEFLT-----PKKLQCVDLH 177 +P +D + + LP +E A G +GWG+++ P LQ V+L Sbjct: 272 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 331 Query: 178 VISNDVCAQVHPQKVTKFMLCAG-RWTGGK--STCSGDSGGPLVCNGVLQ------GITS 228 ++ VC ++T M CAG + GK C GDSGGP V GI S Sbjct: 332 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 391 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTI 257 WG E C + YT V +KWI+ I Sbjct: 392 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 419 >4NZQ-A nrPDB Length = 557 Score = 100 bits (248), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 78/269 (28%), Positives = 119/269 (44%), Gaps = 43/269 (15%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------R 68 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ Sbjct: 295 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 354 Query: 69 NKSVILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127 N ++ +G+HS E + ++ + + HP Y+ ++ D+ L++L Sbjct: 355 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 404 Query: 128 EPAELTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPEEFLT-----PKKLQCVDLH 177 +P +D + + LP +E A G +GWG+++ P LQ V+L Sbjct: 405 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 464 Query: 178 VISNDVCAQVHPQKVTKFMLCAG-RWTGGK--STCSGDSGGPLVCNGVLQ------GITS 228 ++ VC ++T M CAG + GK C GDSGGP V GI S Sbjct: 465 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 524 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTI 257 WG E C + YT V +KWI+ I Sbjct: 525 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 552 >1ETT-H nrPDB Length = 259 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 82/266 (30%), Positives = 120/266 (45%), Gaps = 45/266 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI------RNKSV---- 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ +N +V Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E ++ + + HP Y+ ++ D+ LL+L P E Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 LTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPEEFLT------PKKLQCVDLHVIS 180 L+D + + LP ++ A G +GWG+ E + T P LQ V+L ++ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGN-RRETWTTSVAEVQPSVLQVVNLPLVE 169 Query: 181 NDVCAQVHPQKVTKFMLCAGRWTG-GK--STCSGDSGGPLVCNG------VLQGITSWGS 231 VC ++T M CAG G GK C GDSGGP V GI SWG Sbjct: 170 RPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG- 228 Query: 232 EPCALPERPSLYTKVVHYRKWIKDTI 257 E C + YT V +KWI+ I Sbjct: 229 EGCDRDGKYGFYTHVFRLKKWIQKVI 254 >1PQ7-A nrPDB Length = 224 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 72/235 (30%), Positives = 103/235 (43%), Gaps = 21/235 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRHSLFH 82 IVGG P+ V ++ G CGG L++ VLTAAHC+ +S + R Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQI-RAGSLS 59 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSE--PAELTDAVKVMD 140 G +S HP Y +++DL +L+LS P+ + Sbjct: 60 RTSGGITSSLSSVRVHPSYS-------------GNNNDLAILKLSTSIPSGGNIGYARLA 106 Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-AQVHPQKVTKFMLCA 199 +P G++ +GWG+ TP L V + ++S C AQ +T M CA Sbjct: 107 ASGSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCA 166 Query: 200 GRWTGGKSTCSGDSGGPLV-CNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 G +GGK +C GDSGGP+V + L G SWG CA P +Y V R +I Sbjct: 167 GVSSGGKDSCQGDSGGPIVDSSNTLIGAVSWG-NGCARPNYSGVYASVGALRSFI 220 >2KAI-A nrPDB Length = 80 Score = 97.8 bits (242), Expect = 4e-21, Method: Composition-based stats. Identities = 43/80 (53%), Positives = 56/80 (70%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+GG ECEK+S PWQV + CGGVLV+P+WVLTAAHC + + LGRH+LF E Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 85 DTGQVFQVSHSFPHPLYDMS 104 +T Q F V+ FPHP +++S Sbjct: 61 NTAQFFGVTADFPHPGFNLS 80 >1FIZ-A nrPDB Length = 263 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 74/254 (29%), Positives = 115/254 (45%), Gaps = 21/254 (8%) Query: 25 IVGGWECEKHSQPWQVLVA------SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRH 78 +VGG E + PW V + +R CGG+L++ WVLTAAHC +NK + R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 SLFHPEDT-GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 E G V + ++ +++ +D+ L++++ P + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYV--SGLEINDIALIKITPPVPCGPFIG 118 Query: 138 VMDLPTQE---PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV--HPQKV 192 LP + P TC+ +GWG ++ + T LQ + +I ++C + ++ Sbjct: 119 PGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRI 178 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCNG------VLQGITSWGSEPCALPERPSLYTKV 246 +CAG G TC GDSGGPL+C V+ GITSWG CA +RP +YT Sbjct: 179 RSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVG-CARAKRPGVYTST 237 Query: 247 VHYRKWIKDTIVAN 260 Y WI I +N Sbjct: 238 WPYLNWIASKIGSN 251 >1VR1-H nrPDB Length = 261 Score = 97.4 bits (241), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 76/269 (28%), Positives = 118/269 (43%), Gaps = 47/269 (17%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA------VCGGVLVHPQWVLTAAHCI----------R 68 IV G + E PWQV++ ++ R +CG L+ +WVLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 NKSVILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127 N ++ +G+HS E + ++ + + HP Y+ ++ D+ L++L Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 110 Query: 128 EPAELTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPEEFLT-----PKKLQCVDLH 177 +P +D + + LP +E A G +GWG+++ P LQ V+L Sbjct: 111 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 170 Query: 178 VISNDVCAQVHPQKVTKFMLCA-GRWTGGK--STCSGDSGGPLVCNGVLQ------GITS 228 ++ VC ++T M CA + GK C GDSGGP V GI S Sbjct: 171 IVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 230 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTI 257 WG E C + YT V +KWI+ I Sbjct: 231 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 258 >1FIW-A nrPDB Length = 290 Score = 96.7 bits (239), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 112/251 (44%), Gaps = 21/251 (8%) Query: 25 IVGGWECEKHSQPWQVLVA------SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRH 78 I+GG + + PW V + +R VCGG L++ QW+LTAAHC R K + R Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 SLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 E + G V + ++ ++ ++D+ L++++ P + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKY--SASSEANDIALMKITPPVTCGHFIG 118 Query: 138 VMDLP---TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV--HPQKV 192 LP P + TC+ +GWG ++ T LQ + +I +C + ++ Sbjct: 119 PGCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRI 178 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCNG------VLQGITSWGSEPCALPERPSLYTKV 246 +CAG G TC GDSGGPL+C V+ GITSWG CA +RP +YT Sbjct: 179 RSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVG-CARAKRPGVYTST 237 Query: 247 VHYRKWIKDTI 257 Y WI I Sbjct: 238 WSYLNWIASKI 248 >5XW8-A nrPDB Length = 133 Score = 95.9 bits (237), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 50/138 (36%), Positives = 75/138 (54%), Gaps = 12/138 (8%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +IVGG+ C +S P+QV + S G CGG L++ QWV++AAHC +++ + LG H++ Sbjct: 8 KIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVL 66 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 E Q + HP ++ + L N D+ML++LS PA L V + LP Sbjct: 67 EGNEQFINAAKIITHPNFNGNTLDN-----------DIMLIKLSSPATLNSRVATVSLPR 115 Query: 144 QEPALGTTCYASGWGSIE 161 A GT C SGWG+ + Sbjct: 116 SCAAAGTECLISGWGNTK 133 >1Q3X-A nrPDB Length = 328 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 76/257 (29%), Positives = 115/257 (44%), Gaps = 40/257 (15%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 RI GG + + PWQVL+ G G L++ WVLTAAH + + H Sbjct: 86 RIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQK----------HD 133 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPG----DDSSHDLMLLRLSEPAELTDAVKVM 139 + + P Y + + F+ G +D+ L++L+ + + + Sbjct: 134 ASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPI 193 Query: 140 DLPTQEPA-------LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-- 190 LP +E +GT ASGWG + FL + L VD+ ++ + C + + Sbjct: 194 CLPRKEAESFMRTDDIGT---ASGWG-LTQRGFLA-RNLMYVDIPIVDHQKCTAAYEKPP 248 Query: 191 ----KVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCALPERP 240 VT MLCAG +GGK +C GDSGG LV + GI SWGS C + Sbjct: 249 YPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQY 308 Query: 241 SLYTKVVHYRKWIKDTI 257 +YTKV++Y WI++ I Sbjct: 309 GVYTKVINYIPWIENII 325 >1KIG-H nrPDB Length = 241 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 74/247 (29%), Positives = 113/247 (45%), Gaps = 25/247 (10%) Query: 25 IVGGWECEKHSQPWQ-VLVASRGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRHSLF 81 IVGG +C + PWQ +LV CGG +++ +VLTAAHC+ + + +G + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E +V +M++ +RF++ D D+ +LRL P V L Sbjct: 61 QEEGNEMAHEV---------EMTVKHSRFVKETYD--FDIAVLRLKTPIRFRRNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 P ++ A T T SG+G + L+ L+ +++ + C +T M Sbjct: 110 PEKDWAEATLMTQKTGIVSGFGRTHEKGRLSST-LKMLEVPYVDRSTCKLSSSFTITPNM 168 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKW 252 CAG T + C GDSGGP V + GI SWG E CA + +YTKV ++ KW Sbjct: 169 FCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKFGVYTKVSNFLKW 227 Query: 253 IKDTIVA 259 I + A Sbjct: 228 IDKIMKA 234 >1C5M-D nrPDB Length = 255 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 74/245 (30%), Positives = 110/245 (44%), Gaps = 25/245 (10%) Query: 25 IVGGWECEKHSQPWQ-VLVASRGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRHSLF 81 IVGG EC+ PWQ +L+ CGG ++ ++LTAAHC+ + + +G + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E V +V H NRF + D D+ +LRL P V L Sbjct: 61 QEEGGEAVHEVEVVIKH---------NRFTKETYD--FDIAVLRLKTPITFRMNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 P ++ A T T SG+G E+ +L+ +++ + + C +T+ M Sbjct: 110 PERDWAESTLMTQKTGIVSGFGRTH-EKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNM 168 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKW 252 CAG T + C GDSGGP V + GI SWG E CA + +YTKV + KW Sbjct: 169 FCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKW 227 Query: 253 IKDTI 257 I ++ Sbjct: 228 IDRSM 232 >1YM0-A nrPDB Length = 238 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 78/253 (30%), Positives = 119/253 (47%), Gaps = 32/253 (12%) Query: 25 IVGGWECEKHSQPWQVLV--ASRGRAVCGGVLVHPQWVLTAAHCIRNKS----VILLGRH 78 IVGG E + PWQV V S CGG +++ +WV+ AAHC++ ++ +++G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 Q V F + YD + L+N D+ +++ + +T + V Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLEN-----------DVSVIKTA--VAITFDINV 107 Query: 139 MDLPTQEPA---LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-PQKVTK 194 + +PA + SGWG+I P L+ V L++ +N C V+ + Sbjct: 108 GPICAPDPANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYD 167 Query: 195 FMLCAGRWTG--GKSTCSGDSGGPL-VCNG----VLQGITSWGSEPCALPERPSLYTKVV 247 M+CA TG + +C GDSGGPL V +G L GI SWG CA P +Y++V Sbjct: 168 DMICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGI-GCA-SGYPGVYSRVG 225 Query: 248 HYRKWIKDTIVAN 260 + WI DTI N Sbjct: 226 FHAGWITDTITNN 238 >4FXG-H nrPDB Length = 242 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 74/256 (28%), Positives = 114/256 (44%), Gaps = 40/256 (15%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I GG + + PWQVL+ G G L++ WVLTAAH + + H Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQK----------HDA 48 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPG----DDSSHDLMLLRLSEPAELTDAVKVMD 140 + + P Y + + F+ G +D+ L++L+ + + + Sbjct: 49 SALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPIC 108 Query: 141 LPTQEPA-------LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ--- 190 LP +E +GT ASGWG + FL + L VD+ ++ + C + + Sbjct: 109 LPRKEAESFMRTDDIGT---ASGWG-LTQRGFLA-RNLMYVDIPIVDHQKCTAAYEKPPY 163 Query: 191 ---KVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCALPERPS 241 VT MLCAG +GGK +C GD+GG LV + GI SWGS C + Sbjct: 164 PRGSVTANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYG 223 Query: 242 LYTKVVHYRKWIKDTI 257 +YTKV++Y WI++ I Sbjct: 224 VYTKVINYIPWIENII 239 >1ZJK-A nrPDB Length = 403 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 75/257 (29%), Positives = 115/257 (44%), Gaps = 40/257 (15%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +I GG + + PWQVL+ G G L++ WVLTAAH + + H Sbjct: 161 QIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQK----------HD 208 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPG----DDSSHDLMLLRLSEPAELTDAVKVM 139 + + P Y + + F+ G +D+ L++L+ + + + Sbjct: 209 ASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPI 268 Query: 140 DLPTQEPA-------LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-- 190 LP +E +GT ASGWG + FL + L VD+ ++ + C + + Sbjct: 269 CLPRKEAESFMRTDDIGT---ASGWG-LTQRGFLA-RNLMYVDIPIVDHQKCTAAYEKPP 323 Query: 191 ----KVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCALPERP 240 VT MLCAG +GGK +C GDSGG LV + GI SWGS C + Sbjct: 324 YPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQY 383 Query: 241 SLYTKVVHYRKWIKDTI 257 +YTKV++Y WI++ I Sbjct: 384 GVYTKVINYIPWIENII 400 >2XXL-A nrPDB Length = 408 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 75/268 (27%), Positives = 119/268 (44%), Gaps = 33/268 (12%) Query: 20 LILSRIVGGWECEKHSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCI----RNKS 71 + R+ G+E + S+PW L+ R +CGG ++ +++LTAAHC+ + Sbjct: 114 FLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLY 173 Query: 72 VILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS--HDLMLLRLSEP 129 I LG H + ED Q + P P+ ++ + K+ D HD+ LL+L+ Sbjct: 174 EIRLGEHRISTEEDCRQQGRKKKCAP-PVVNVGIEKHLIHEKYDARHIMHDIALLKLNRS 232 Query: 130 AELTDAVKVMDLP-----TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC 184 +K + LP ++ +T + +GWG+ E + L ++ + C Sbjct: 233 VPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTTENGS--SSDVLLQANVPLQPRSAC 290 Query: 185 AQVHPQKVTKFMLCAGRWTGG--KSTCSGDSGGPLVCNG----------VLQGITSWGSE 232 +Q + + V LC G GG + +C GDSGGPL V GI S G Sbjct: 291 SQAYRRAVPLSQLCVG---GGDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVV 347 Query: 233 PCALPERPSLYTKVVHYRKWIKDTIVAN 260 C P LYT V Y +WI DT+ +N Sbjct: 348 TCGQISLPGLYTNVGEYVQWITDTMASN 375 >2OLG-A nrPDB Length = 278 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 72/269 (26%), Positives = 123/269 (45%), Gaps = 47/269 (17%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRA-----VCGGVLVHPQWVLTAAHCIRNKSVILLGR 77 +I+ G + PW ++ + + CGG L++ ++++TAAHC+ + + ++G Sbjct: 21 DKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGA 80 Query: 78 ---------HSLFHPEDTGQV----------FQVSHSFPHPLYDMSLLKNRFLRPGDDSS 118 ++ P+ G V + + HP Y + K+R+ Sbjct: 81 LNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDY-VDGSKDRY-------- 131 Query: 119 HDLMLLRLSEPAELTDAVKVMDL--PTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDL 176 HD+ L+RL+ E T+ ++ + L P +E +G GWG E ++ T K Q + + Sbjct: 132 HDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIK--QKLAV 189 Query: 177 HVISNDVCAQVHPQ---KVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGV-----LQGITS 228 V+ + CA+ +V LCAG K +C GDSGGPL+ L+G+ S Sbjct: 190 PVVHAEQCAKTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVS 248 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTI 257 +G+ C P +YTKV YR WI+ I Sbjct: 249 FGA-TCGTEGWPGIYTKVGKYRDWIEGNI 276 >5TO3-B nrPDB Length = 409 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 74/265 (27%), Positives = 116/265 (43%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E + ++ + + HP Y+ ++ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 LTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPEEFLT-----PKKLQCVDLHVISN 181 +D + + LP +E A G +GWG+++ P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 170 Query: 182 DVCAQVHPQKVTKFMLCAG-RWTGGK--STCSGDSGGPLVCNGVLQ------GITSWGSE 232 VC ++T M CAG + GK C GDSGGP V GI S G+ Sbjct: 171 PVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAG 230 Query: 233 PCALPERPSLYTKVVHYRKWIKDTI 257 C + YT V +KWI+ I Sbjct: 231 -CDRDGKYGFYTHVFRLKKWIQKVI 254 >4KKD-A nrPDB Length = 433 Score = 87.4 bits (215), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 80/281 (28%), Positives = 120/281 (42%), Gaps = 59/281 (20%) Query: 19 PLILSRIVGGWECEKHSQPWQVLVASRGRA-------VCGGVLVHPQWVLTAAHCIRNKS 71 P ++ RI+GG E PWQ L+ + G L+ W+LTAAH +R++ Sbjct: 149 PSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQR 208 Query: 72 -------------VILLGRHSLFHPEDTGQV-FQVSHSFPHPLYDMSLLKNRFLRPGDDS 117 + LG H + + +G V + HP +++ + Sbjct: 209 RDTTVIPVSKEHVTVYLGLHDVR--DKSGAVNSSAARVVLHPDFNIQ-----------NY 255 Query: 118 SHDLMLLRLSEPAELTDAVKVMDLPTQEP---ALGTTCYASGWGSIEP----EEFLTPKK 170 +HD+ L++L EP L V + LP EP A +GWG P +E ++ Sbjct: 256 NHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGT 315 Query: 171 ------LQCVDLHVISNDVCAQVHPQK-----VTKFMLCAGRWTGGKSTCSGDSGGPLVC 219 LQ V L V+ + C + + VT+ M CAG + GGK TC GDSG V Sbjct: 316 RTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVI 375 Query: 220 NG------VLQGITSWGS-EPCALPERPSLYTKVVHYRKWI 253 V+QG+ SWG E C + +YTKV +Y W+ Sbjct: 376 FDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV 416 >4LK4-A nrPDB Length = 357 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 117/253 (46%), Gaps = 38/253 (15%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRGR-----AVCGGVLVHPQWVLTAAHCIRNKSV--- 72 I SRI+ G P V + RG CGG + ++VLTAAHC ++S Sbjct: 7 ISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASV 66 Query: 73 -ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 +++G + L + G+ + H Y S L N D+ ++ L++ + Sbjct: 67 DVIIGAYDL-NNSSQGERIAAQKIYRHLSYSPSNLLN-----------DIAIVELAQTSS 114 Query: 132 LTDAVKVMDLPTQE--PALGTTCYASGWG---SIEPEEFLTPKKLQCVDLHVISNDVCAQ 186 L A+ + T+ PAL T +GWG +P +F TP LQ VD+ ++S +C Sbjct: 115 LP-AITLAGPATRTSLPAL-TPLTVAGWGITVQSKPPQF-TPI-LQEVDVDLVSQSLCQI 170 Query: 187 VHPQKVTK----FMLCAGRWTGGKSTCSGDSGGPLVCN-GVLQ-GITSWGSEPCALPERP 240 V ++ CA R T K +C GD+GGP+V G Q GI SWG E CA Sbjct: 171 VMQHGISSDPNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTY 228 Query: 241 SLYTKVVHYRKWI 253 +YT V ++R WI Sbjct: 229 GVYTNVSYFRDWI 241 >4IW4-E nrPDB Length = 279 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 79/275 (28%), Positives = 117/275 (42%), Gaps = 59/275 (21%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA-------VCGGVLVHPQWVLTAAHCIRNKS------ 71 I+GG E PWQ L+ + G L+ W+LTAAH +R++ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 72 -------VILLGRHSLFHPEDTGQVFQ-VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLML 123 + LG H + + +G V + HP +++ + +HD+ L Sbjct: 61 PVSKEHVTVYLGLHDVR--DKSGAVNSSAARVVLHPDFNIQ-----------NYNHDIAL 107 Query: 124 LRLSEPAELTDAVKVMDLPTQEP---ALGTTCYASGWGSIEP----EEFLTPKK------ 170 ++L EP L V + LP EP A +GWG P +E ++ Sbjct: 108 VQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDV 167 Query: 171 LQCVDLHVISNDVCAQVHPQK-----VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG---- 221 LQ V L V+ + C + + VT+ M CAG + GGK TC GDSGG V Sbjct: 168 LQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQ 227 Query: 222 --VLQGITSWGS-EPCALPERPSLYTKVVHYRKWI 253 V+QG+ SWG E C + +YTKV +Y W+ Sbjct: 228 RWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV 262 >2HLC-A nrPDB Length = 230 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 68/243 (27%), Positives = 107/243 (44%), Gaps = 33/243 (13%) Query: 25 IVGGWECEKHSQPWQ----VLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+ G+E P+Q + + + R CGG L+ +W+LTAAHC+ + +++ S Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 81 FHPEDTGQVFQ---VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 E V +SHS +P D +D+ L+++ E TD ++ Sbjct: 61 VQYEGEAVVNSERIISHSMFNP---------------DTYLNDVALIKIPH-VEYTDNIQ 104 Query: 138 VMDLPTQEPALGTT----CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVT 193 + LP+ E SGWG + + LQ VI ND CAQ +P + Sbjct: 105 PIRLPSGEELNNKFENIWATVSGWGQSNTDTVI----LQYTYNLVIDNDRCAQEYPPGII 160 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVCN--GVLQGITSWGSEPCALPERPSLYTKVVHYRK 251 G + GKS C GDSGGP V + +L G+ S+ S +P +++V Y Sbjct: 161 VESTICGDTSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMD 220 Query: 252 WIK 254 WI+ Sbjct: 221 WIQ 223 >4BXW-A nrPDB Length = 423 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 72/243 (29%), Positives = 106/243 (43%), Gaps = 17/243 (6%) Query: 24 RIVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVI--LLGRHSL 80 RIV G +C+ PWQ LV + CGG ++ P +VLTAAHCI I ++G Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDK 228 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E TG + V + H + +F D +D+ ++++ P + ++ V Sbjct: 229 SRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYD--YDIAIIQMKTPIQFSENVVPAC 285 Query: 141 LPTQEPALGTTC-----YASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKF 195 LPT + A SG+G I E+ K L+ + + + C +T Sbjct: 286 LPTADFANQVLMKQDFGIVSGFGRI-VEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPN 344 Query: 196 MLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHYRK 251 M CAG T + C GDSGGP + GI S G E CA + YTK+ + Sbjct: 345 MFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSG-EGCARNGKYGNYTKLSKFIP 403 Query: 252 WIK 254 WIK Sbjct: 404 WIK 406 >6BQM-A nrPDB Length = 506 Score = 77.4 bits (189), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 69/263 (26%), Positives = 112/263 (42%), Gaps = 39/263 (14%) Query: 16 GAAPLILSRIVGGWECEKHSQPWQVLVASRGRA--VCGGVLVHPQWVLTAAHCIRN---- 69 G + SRI+GG + P+ V + +R + CGG + ++VLTAAHC+ Sbjct: 2 GTESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPA 61 Query: 70 KSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS-- 127 K +LLG + + +T + V + H Y + + N D+ +L L Sbjct: 62 KGDVLLGAFDM-NDVNTAERIHVRQIYVHNSYITASMGN-----------DIAVLELERD 109 Query: 128 ----EPAELTDAVKVMDLPTQEP----ALGTTCYASGWGSIEPEEFLTPKKLQCVDL--- 176 +++D+ +L P G G S +P L ++ V L Sbjct: 110 PLPRRSVQISDSSDFNELTKDSPMTVIGFGNRKEVDGEKS-DPATILHQVQVPFVPLPEC 168 Query: 177 HVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLV---CNGVLQ-GITSWGSE 232 +D A+ + ++T CAG + GK CSGD+GGP+ NG Q G+ SWG + Sbjct: 169 KTKGSDQDAKNNYSQLTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWG-D 225 Query: 233 PCALPERPSLYTKVVHYRKWIKD 255 C P +YT + + W+ D Sbjct: 226 GCGRANSPGVYTNLSVFNDWLDD 248 >2B9L-A nrPDB Length = 394 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 76/265 (28%), Positives = 107/265 (40%), Gaps = 51/265 (19%) Query: 30 ECEKHSQPWQVLV--------ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 E E PW V V + + VCGG L+ P VLT AHC+ + L Sbjct: 136 EAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRA 195 Query: 82 HPEDT--------GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELT 133 DT Q ++ H ++ + N D+ LL L P Sbjct: 196 GEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVN-----------DVALLLLDRPLVQA 244 Query: 134 DAVKVMDLPTQEPALGTT-CYASGWGSIEPEEFLTPKK----LQCVDLHVISNDVC-AQV 187 D + + LP Q +T C+ASGWG +EF + + L+ + L + D C A + Sbjct: 245 DNIGTICLPQQSQIFDSTECFASGWGK---KEFGSRHRYSNILKKIQLPTVDRDKCQADL 301 Query: 188 HPQKVT-KFML-----CAGRWTGGKSTCSGDSGGPLVC-------NGVLQGITSWGSEPC 234 ++ KF+L CAG GK TC+GD G PL C + GI +WG C Sbjct: 302 RNTRLGLKFVLDQTFVCAG-GEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI-GC 359 Query: 235 ALPERPSLYTKVVHYRKWIKDTIVA 259 P +Y V H+R WI + A Sbjct: 360 GDENVPGVYANVAHFRNWIDQEMQA 384 >2ASU-B nrPDB Length = 234 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 68/230 (29%), Positives = 99/230 (43%), Gaps = 19/230 (8%) Query: 35 SQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVS 93 + PW V + +R G+ CGG LV QW+LTA C + + L G G +FQ Sbjct: 8 NSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL-----GTLFQNP 62 Query: 94 HSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL--GTT 151 L + + K S L+LL+L L V ++ LP + + GT Sbjct: 63 QHGEPSLQRVPVAKMVC----GPSGSQLVLLKLERSVTLNQRVALICLPPEWYVVPPGTK 118 Query: 152 CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 211 C +GWG E + L L+VISN C H +V + +C C G Sbjct: 119 CEIAGWG--ETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPVGACEG 176 Query: 212 DSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 D GGPL C + VL+GI + CA P+++T+V + WI + Sbjct: 177 DYGGPLACFTHNSWVLEGIII-PNRVCARSRWPAVFTRVSVFVDWIHKVM 225 >2JET-B nrPDB Length = 128 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 15/131 (11%) Query: 35 SQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHC-IRNKSVILLGRHSLFHPEDTGQVFQV 92 S PWQV + + G CGG L+ WV+TAAHC ++ V++ G E+ QV ++ Sbjct: 8 SWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEENIQVLKI 67 Query: 93 SHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL--GT 150 + F +P ++M ++N D+ LL+L+ PA+ ++ V + LP + GT Sbjct: 68 AQVFKNPKFNMFTVRN-----------DITLLKLATPAQFSETVSAVCLPNVDDDFPPGT 116 Query: 151 TCYASGWGSIE 161 C +GWG + Sbjct: 117 VCATTGWGKTK 127 >5UBM-A nrPDB Length = 252 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 74/260 (28%), Positives = 108/260 (41%), Gaps = 37/260 (14%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKS--VILLGRHSLF 81 RI+GG + + + PWQV + GG L++ WVLTAAH + + +G S+ Sbjct: 1 RIIGGSDADIKNFPWQVFFDN---PWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 82 HPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 ++ H F HP + LL+ R D +D+ L+RL +P ++ V + Sbjct: 58 TSRLAKSKMLTPEHVFIHPGW--KLLEVPEGRTNFD--NDIALVRLKDPVKMGPTVSPIC 113 Query: 141 LPTQEPAL----GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK----- 191 LP G SGWG E + +L+ L V C +V +K Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRDRAV--RLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 192 ----VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPERP 240 T M+CAG G +C GDSGG G+ SWG + C Sbjct: 172 EAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---Y 226 Query: 241 SLYTKVVHYRKWIKDTIVAN 260 LYT+V +Y WI T+ N Sbjct: 227 GLYTRVKNYVDWIMKTMQEN 246 >1MD7-A nrPDB Length = 328 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 69/248 (27%), Positives = 102/248 (41%), Gaps = 21/248 (8%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 RI+GG + + + PWQV GR GG L+ +W+LTAAH + K SL Sbjct: 88 QRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDV 145 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 V ++ HP+ +S+ + + D+ LL L L + + LP Sbjct: 146 FLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLP 205 Query: 143 TQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-----AQVHPQKVTKF 195 + LG Y SG+G +E + L+ V L V + C + ++ Sbjct: 206 DNDTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQN 262 Query: 196 MLCAGRWTGGKSTCSGDSGG------PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHY 249 M CAG + + C GD+GG P V GI SWG YTKV++Y Sbjct: 263 MFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKVLNY 319 Query: 250 RKWIKDTI 257 WIK + Sbjct: 320 VDWIKKEM 327 >1ELV-A nrPDB Length = 333 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 71/261 (27%), Positives = 110/261 (42%), Gaps = 39/261 (14%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRHSLF 81 RI+GG + + + PWQV + GG L++ WVLTAAH + + + +G S+ Sbjct: 82 RIIGGSDADIKNFPWQVFFDN---PWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 138 Query: 82 HPE-DTGQVFQVSHSFPHPLYD-MSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 ++ H F HP + +++ + R + +D+ L+RL +P ++ V + Sbjct: 139 TSRLAKSKMLTPEHVFIHPGWKLLAVPEGR-----TNFDNDIALVRLKDPVKMGPTVSPI 193 Query: 140 DLPTQEPAL----GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK---- 191 LP G SGWG E + +L+ L V C +V +K Sbjct: 194 CLPGTSSDYNLMDGDLGLISGWGRTEKRDRAV--RLKAARLPVAPLRKCKEVKVEKPTAD 251 Query: 192 -----VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPER 239 T M+CAG G +C GDSGG G+ SWG + C Sbjct: 252 AEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT--- 306 Query: 240 PSLYTKVVHYRKWIKDTIVAN 260 LYT+V +Y WI T+ N Sbjct: 307 YGLYTRVKNYVDWIMKTMQEN 327 >2QY0-B nrPDB Length = 242 Score = 72.0 bits (175), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 101/246 (41%), Gaps = 21/246 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+GG + + + PWQV GR GG L+ +W+LTAAH + K SL Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 V ++ HP+ +S+ + + D+ LL L L + + LP Sbjct: 59 GHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDN 118 Query: 145 EP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-----AQVHPQKVTKFML 197 + LG Y SG+G +E + L+ V L V + C + ++ M Sbjct: 119 DTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 198 CAGRWTGGKSTCSGDSGG------PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 251 CAG + + C GDSGG P V GI SWG YTKV++Y Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKVLNYVD 232 Query: 252 WIKDTI 257 WIK + Sbjct: 233 WIKKEM 238 >3RU4-E nrPDB Length = 96 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 42/98 (42%), Positives = 55/98 (56%), Gaps = 7/98 (7%) Query: 167 TPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV-- 222 TP +LQ L ++SN C + K+ M+CAG G S+C GDSGGPLVC NG Sbjct: 2 TPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWT 59 Query: 223 LQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 L GI SWGS C+ P +Y +V W++ T+ AN Sbjct: 60 LVGIVSWGSSTCS-TSTPGVYARVTALVNWVQQTLAAN 96 >1GPZ-A nrPDB Length = 399 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 69/248 (27%), Positives = 102/248 (41%), Gaps = 21/248 (8%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +I+GG + + + PWQV GR GG L+ +W+LTAAH + K SL Sbjct: 156 QQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDV 213 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 V ++ HP+ +S+ + + D+ LL L L + + LP Sbjct: 214 FLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLP 273 Query: 143 TQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-----AQVHPQKVTKF 195 + LG Y SG+G +E + L+ V L V + C + ++ Sbjct: 274 DNDTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQN 330 Query: 196 MLCAGRWTGGKSTCSGDSGG------PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHY 249 M CAG + + C GDSGG P V GI SWG YTKV++Y Sbjct: 331 MFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKVLNY 387 Query: 250 RKWIKDTI 257 WIK + Sbjct: 388 VDWIKKEM 395 >4J1Y-A nrPDB Length = 397 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 73/261 (27%), Positives = 109/261 (41%), Gaps = 37/261 (14%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR--NKSVILLGRHSL 80 +R +GG + + + PWQV + GG L++ WVLTAAH + + + +G S+ Sbjct: 145 ARAIGGSDADIKNFPWQVFFDN---PWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSV 201 Query: 81 FHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 ++ H F HP + LL+ R D +D+ L+RL +P ++ V + Sbjct: 202 QTSRLAKSKMLTPEHVFIHPGW--KLLEVPEGRTNFD--NDIALVRLKDPVKMGPTVSPI 257 Query: 140 DLPTQEPAL----GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK---- 191 LP G SGWG E + +L+ L V C +V +K Sbjct: 258 CLPGTSSDYNLMDGDLGLISGWGRTEKRDRAV--RLKAARLPVAPLRKCKEVKVEKPTAD 315 Query: 192 -----VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPER 239 T M+CAG G +C GDSGG G+ SWG + C Sbjct: 316 AEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT--- 370 Query: 240 PSLYTKVVHYRKWIKDTIVAN 260 LYT+V +Y WI T+ N Sbjct: 371 YGLYTRVKNYVDWIMKTMQEN 391 >3VGC-B nrPDB Length = 131 Score = 70.5 bits (171), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 44/138 (31%), Positives = 66/138 (47%), Gaps = 15/138 (10%) Query: 25 IVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHC-IRNKSVILLGRHSLFH 82 IV G E S PWQV + + G CGG L++ WV+TAAHC + V++ G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 + Q +++ F + Y+ + N D+ LL+LS A + V + LP Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTINN-----------DITLLKLSTAASFSQTVSAVCLP 109 Query: 143 --TQEPALGTTCYASGWG 158 + + A GTTC +GWG Sbjct: 110 SASDDFAAGTTCVTTGWG 127 >3H7T-A nrPDB Length = 235 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 65/246 (26%), Positives = 107/246 (43%), Gaps = 31/246 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK--SVILLGRHSLFH 82 I+GG + + +PW V V + CGG ++ +V+TAA C+ S I + S + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGSSYR 60 Query: 83 PEDTGQVF--QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTD-AVKVM 139 V ++ HPL ++N + ++ P +L D K + Sbjct: 61 TTKGTSVMAKKIYIVRYHPL----TMQNNY-----------AVIETEMPIKLDDKTTKKI 105 Query: 140 DLPT--QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVTKFM 196 +LP+ +P T+ SGWGS + L + V+ C + + Q + K++ Sbjct: 106 ELPSLLYDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYI 165 Query: 197 ----LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALP-ERPSLYTKVVHYRK 251 CAG GD+G P V NG L G+ S+ S ++P E PS++ +V +Y Sbjct: 166 YDGVFCAGGEYDETYIGYGDAGDPAVQNGTLVGVASYIS---SMPSEFPSVFLRVGYYVL 222 Query: 252 WIKDTI 257 IKD I Sbjct: 223 DIKDII 228 >1M9U-A nrPDB Length = 241 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 52/152 (34%), Positives = 70/152 (46%), Gaps = 15/152 (9%) Query: 118 SHDLMLLRLSEPAELTDAVKVMDLP--TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVD 175 S+D+ +L L+ L ++ LP GTTC SGWG + L P LQ Sbjct: 91 SNDIAILHLATSISLGGNIQAAVLPANNNNDYAGTTCVISGWGRTDGTNNL-PDILQKSS 149 Query: 176 LHVISNDVCAQ----VHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC-NGVLQ--GITS 228 + VI+ C V + +C G C+GDSGGPL C +G + G+TS Sbjct: 150 IPVITTAQCTAAMVGVGGANIWDNHICVQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTS 209 Query: 229 W----GSEPCALPERPSLYTKVVHYRKWIKDT 256 W G C LP+ PS+YT+V Y WI D Sbjct: 210 WVVSSGLGAC-LPDYPSVYTRVSAYLGWIGDN 240 >2JET-C nrPDB Length = 99 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 41/98 (41%), Positives = 55/98 (56%), Gaps = 7/98 (7%) Query: 167 TPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC--NGV-- 222 TP+KLQ L ++S C + K+T M CAG G +C GDSGGPLVC +GV Sbjct: 5 TPEKLQQAALPIVSEADCKKSWGSKITDVMTCAG--ASGVDSCMGDSGGPLVCQKDGVWT 62 Query: 223 LQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 L GI SWGS C+ P +Y++V W++ + AN Sbjct: 63 LAGIVSWGSGVCST-STPGVYSRVTALMPWVQQILEAN 99 >2FMJ-A nrPDB Length = 222 Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 68/242 (28%), Positives = 104/242 (42%), Gaps = 40/242 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 +VGG + P+ V ++ CGG L VLTAAHC+ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPG-DDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 TG V + S + +L+ PG + + D L++L++P ++ PT Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQ----APGYNGTGKDWALIKLAQP---------INQPT 96 Query: 144 QEPALGTTCY------ASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VTKFM 196 + A TT Y +GWG+ E + L ++ +S+ C + + V Sbjct: 97 LKIAT-TTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEE 154 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNG-----VLQGITSWGSEPCALPERPSLYTKVVHYRK 251 +CAG TGG TC GDSGGP+ + GI SWG E CA + +YT+V + Sbjct: 155 ICAGYDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-EGCARKGKYGVYTEVSTFAS 213 Query: 252 WI 253 I Sbjct: 214 AI 215 >3H7O-A nrPDB Length = 228 Score = 67.0 bits (162), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 110/247 (44%), Gaps = 39/247 (15%) Query: 27 GGWECEKHSQPWQVLVAS---RGRAVCGGVLVHPQWVLTAAHCIRNK--SVILLGRHSLF 81 GG + + PW V V + CGG ++ +VLTAAHC+ ++ I++ S Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 82 HPEDTGQVF-QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTD-AVKVM 139 ED G+ VSH + +S + + +D+ +L LS P +L K Sbjct: 62 LWEDPGKSDPYVSHVY------LSFYRQETME------NDIAILELSRPLKLDGLKSKPA 109 Query: 140 DLPTQE--PALGTTCYASGWGSIEPEEFLTPK--KLQCVDLHVISNDVC-AQVHPQKVTK 194 LP E P G+ SG+G + + PK L+ L V+ D C + P ++ Sbjct: 110 KLPDIEFRPKTGSDVLVSGYGD---GQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSL 166 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER----PSLYTKVVHYR 250 + CA + G S SGD+G P V L G+ ++ P+R P ++TKV Y Sbjct: 167 QVFCAQKV--GVSLESGDAGDPTVQQDTLVGVAAY------FPKRPEGAPEVFTKVGSYV 218 Query: 251 KWIKDTI 257 WI+D I Sbjct: 219 SWIQDII 225 >4X0L-C nrPDB Length = 259 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 69/267 (25%), Positives = 109/267 (40%), Gaps = 47/267 (17%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA-HCIRNKSVILLGRH-- 78 + RI+GG K S PWQ + S G L++ QW+LT A + N S + Sbjct: 12 VQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIA 71 Query: 79 -SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 +L Q+ ++ HP Y S D+ L++L + + + V Sbjct: 72 PTLTLYVGKKQLVEIEKVVLHPNY---------------SQVDIGLIKLKQKVSVNERVM 116 Query: 138 VMDLPTQEPA-LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-----PQK 191 + LP+++ A +G Y SGWG F L+ V L V D C + + P+K Sbjct: 117 PICLPSKDYAEVGRVGYVSGWG--RNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEK 174 Query: 192 VT------------KFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQ------GITSWGSEP 233 T + CAG + TC GD+G + + + GI S+ + Sbjct: 175 KTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF-DKS 233 Query: 234 CALPERPSLYTKVVHYRKWIKDTIVAN 260 CA+ E +Y KV + W++ TI N Sbjct: 234 CAVAEY-GVYVKVTSIQDWVQKTIAEN 259 >3I77-A nrPDB Length = 230 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 71/246 (28%), Positives = 102/246 (41%), Gaps = 40/246 (16%) Query: 25 IVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +VGG + P+ V L+ CGG L VLTAAHC+ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVS-------GSGNNTSI 53 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPG---DDSSHDLMLLRLSEPAELTDAVKVMD 140 TG V + S + +L+ PG + D L++L++P ++ Sbjct: 54 TATGGVVDLQSSSAVKVRSTKVLQ----APGFTKETYGKDWALIKLAQP---------IN 100 Query: 141 LPTQEPALGTTCY------ASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VT 193 PT + A TT Y +GWG+ E + L ++ +S+ C V Sbjct: 101 QPTLKIAT-TTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVA 158 Query: 194 KFMLCAGR-WTGGKSTCSGDSGGPLVCNG-----VLQGITSWGSEPCALPERPSLYTKVV 247 M+CAG TGG TC GDSGGP+ + GI SWG CA P P +YT+V Sbjct: 159 NEMICAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVS 217 Query: 248 HYRKWI 253 + I Sbjct: 218 TFASAI 223 >4WJG-C nrPDB Length = 315 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 69/267 (25%), Positives = 109/267 (40%), Gaps = 47/267 (17%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA-HCIRNKSVILLGRH-- 78 + RI+GG K S PWQ + S G L++ QW+LT A + N S + Sbjct: 68 VQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIA 127 Query: 79 -SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 +L Q+ ++ HP Y S D+ L++L + + + V Sbjct: 128 PTLTLYVGKKQLVEIEKVVLHPNY---------------SQVDIGLIKLKQKVSVNERVM 172 Query: 138 VMDLPTQEPA-LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-----PQK 191 + LP+++ A +G Y SGWG F L+ V L V D C + + P+K Sbjct: 173 PICLPSKDYAEVGRVGYVSGWG--RNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEK 230 Query: 192 VT------------KFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQ------GITSWGSEP 233 T + CAG + TC GD+G + + + GI S+ + Sbjct: 231 KTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF-DKS 289 Query: 234 CALPERPSLYTKVVHYRKWIKDTIVAN 260 CA+ E +Y KV + W++ TI N Sbjct: 290 CAVAEY-GVYVKVTSIQDWVQKTIAEN 315 >2I6S-A nrPDB Length = 517 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 65/237 (27%), Positives = 103/237 (43%), Gaps = 39/237 (16%) Query: 32 EKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT-GQVF 90 ++ PW V + + + C G L+ QWVLTAAHC R+ + L R ++ P+ G+ F Sbjct: 239 DQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEF 298 Query: 91 QVSHSFPHPLYDMSLLKNRFLRP--GDDSSHDLMLLRLSEPAELTDAVKVMDLP-TQEPA 147 + + P +D+ KN+ + GD D+ LL+L++ +++ + + LP T E Sbjct: 299 LIEKAVISPGFDVFAKKNQGILEFYGD----DIALLKLAQKVKMSTHARPICLPCTMEAN 354 Query: 148 L------GTTCYASGWGSIE----PEEF--LTPKKLQCVDLHVISNDVCAQVHPQKVTKF 195 L G+TC + P F L KL + CA+V Q+ T F Sbjct: 355 LALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMF 414 Query: 196 -------------MLCAGRWTGGKSTCSGDSGGPLVCNGVLQ----GITSWG-SEPC 234 LC+G +S C G+SGG + + G+ SWG PC Sbjct: 415 PNLTDVREVVTDQFLCSGTQE-DESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPC 470 >4F4O-C nrPDB Length = 347 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 66/263 (25%), Positives = 107/263 (40%), Gaps = 39/263 (14%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 + RI+GG K S PWQ + S G L++ QW+LT A +R LG + Sbjct: 100 VQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLR------LGHKNDT 153 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 +D ++ + ++ P D+S+ D+ L++L + + + V + L Sbjct: 154 KAKDIAPTLRLYVGKKQEVE----IEKVIFHP-DNSTVDIGLIKLKQKVPVNERVMPICL 208 Query: 142 PTQEPA-LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-----PQKVT-- 193 P+++ +G Y SGWG F + L+ V L V + C Q + P+K T Sbjct: 209 PSKDYVNVGLVGYVSGWGRNANLNFT--EHLKYVMLPVADQEKCVQYYEGSTVPEKKTPK 266 Query: 194 ----------KFMLCAGRWTGGKSTCSGDSGGPLVCNG------VLQGITSWGSEPCALP 237 + CAG + TC GD+G + GI S+ + C Sbjct: 267 SPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSF-DKSCRTA 325 Query: 238 ERPSLYTKVVHYRKWIKDTIVAN 260 E +Y +V WI+ TI N Sbjct: 326 EY-GVYVRVTSILDWIQTTIADN 347 >1RIW-B nrPDB Length = 147 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 28/155 (18%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E + ++ + + HP Y+ ++ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 LTDAVKVMDLPTQEPA-----LGTTCYASGWGSIE 161 +D + + LP +E A G +GWG+++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLK 145 >3BEU-A nrPDB Length = 224 Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 70/244 (28%), Positives = 102/244 (41%), Gaps = 42/244 (17%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 +VGG + P+ V + S G CGG L VLTAAHC+ G + Sbjct: 1 VVGGTRAAQGEFPFMVRL-SMG---CGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPG---DDSSHDLMLLRLSEPAELTDAVKVMDL 141 TG V + S + +L+ PG + D L++L++P ++ Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQ----APGFTKETYGKDWALIKLAQP---------INQ 96 Query: 142 PTQEPALGTTCY------ASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VTK 194 PT + A TT Y +GWG+ E + L ++ +S+ C V Sbjct: 97 PTLKIAT-TTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVAN 154 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNG-----VLQGITSWGSEPCALPERPSLYTKVVHY 249 M+CAG T + TC GDSGGP+ V GI SWG E CA + +YT+V + Sbjct: 155 EMICAGYDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWG-EGCARKGKYGVYTEVSTF 213 Query: 250 RKWI 253 I Sbjct: 214 ASAI 217 >1BBR-H nrPDB Length = 150 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 43/153 (28%), Positives = 72/153 (47%), Gaps = 28/153 (18%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI------RNKSV---- 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ +N +V Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E ++ + + HP Y+ ++ D+ LL+L P E Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 LTDAVKVMDLPTQEPA-----LGTTCYASGWGS 159 L+D + + LP ++ A G +GWG+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGN 143 >1BBR-E nrPDB Length = 109 Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 37/101 (36%), Positives = 46/101 (45%), Gaps = 10/101 (9%) Query: 166 LTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG-GK--STCSGDSGGPLVCNGV 222 + P LQ V+L ++ VC ++T M CAG G GK C GDSGGP V Sbjct: 5 VQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSP 64 Query: 223 LQ------GITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 GI SWG E C + YT V +KWI+ I Sbjct: 65 YNNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 104 >2HNT-F nrPDB Length = 105 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 36/99 (36%), Positives = 45/99 (45%), Gaps = 10/99 (10%) Query: 168 PKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAG-RWTGGK--STCSGDSGGPLVCNGVLQ 224 P LQ V+L ++ VC ++T M CAG + GK C GDSGGP V Sbjct: 3 PSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFN 62 Query: 225 ------GITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 GI SWG E C + YT V +KWI+ I Sbjct: 63 NRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 100 >1EPT-B nrPDB Length = 82 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 11/89 (12%) Query: 73 ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 + LG H++ E Q + HP ++ + L N D+ML++LS PA L Sbjct: 5 VRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDN-----------DIMLIKLSSPATL 53 Query: 133 TDAVKVMDLPTQEPALGTTCYASGWGSIE 161 V + LP A GT C SGWG+ + Sbjct: 54 NSRVATVSLPRSCAAAGTECLISGWGNTK 82 >2WIN-I nrPDB Length = 507 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 63/245 (25%), Positives = 102/245 (41%), Gaps = 49/245 (20%) Query: 29 WECEK----HSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 WE K H QPWQ ++ S+G C G +V +VLTAAHC + HS+ Sbjct: 223 WEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSI 278 Query: 81 -FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 + ++ HP Y+++ K + D +D+ L++L + ++ + Sbjct: 279 KVSVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYD--YDVALIKLKNKLKYGQTIRPI 336 Query: 140 DLPTQEPAL-------GTTCYASGWGSIEPEE----FLT--PKKLQCVDLHVISND---V 183 LP E TTC + ++ F++ KKL ++++ + D Sbjct: 337 CLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 396 Query: 184 C---AQVHP---------QKVTKFMLCAGRWT--GGKSTCSGDSGGPLVCNG----VLQG 225 C AQ P + VT LC G + +TC GDSGGPL+ + + G Sbjct: 397 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 456 Query: 226 ITSWG 230 + SWG Sbjct: 457 VISWG 461 >1DLE-A nrPDB Length = 298 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 63/245 (25%), Positives = 99/245 (40%), Gaps = 49/245 (20%) Query: 29 WECEK----HSQPWQ----VLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 WE K H QPWQ V+ S+G C G +V +VLTAAHC + HS+ Sbjct: 16 WEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSI 71 Query: 81 -FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 + ++ HP Y+++ K + D +D+ L++L + ++ + Sbjct: 72 KVSVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYD--YDVALIKLKNKLKYGQTIRPI 129 Query: 140 DLPTQEPAL-------GTTCYASGWGSIEPEEFLT------PKKLQCVDLHVISND---V 183 LP E TTC + ++ KKL ++++ + D Sbjct: 130 CLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGS 189 Query: 184 C---AQVHP---------QKVTKFMLCAGRWT--GGKSTCSGDSGGPLVCNG----VLQG 225 C AQ P + VT LC G + +TC GDSGGPL+ + + G Sbjct: 190 CERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVG 249 Query: 226 ITSWG 230 + SWG Sbjct: 250 VISWG 254 >2OK5-A nrPDB Length = 752 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 65/251 (25%), Positives = 100/251 (39%), Gaps = 61/251 (24%) Query: 29 WECEK----HSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 WE K H QPWQ ++ S+G C G +V +VLTAAHC + HS+ Sbjct: 467 WEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSI 522 Query: 81 -FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 + ++ HP Y+++ K + D +D+ L++L + ++ + Sbjct: 523 KVSVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYD--YDVALIKLKNKLKYGQTIRPI 580 Query: 140 DLPTQEPAL-------GTTCYASGWGSIEPEEFL------------TPKKLQCVDLHVIS 180 LP E TTC + EE L KKL ++++ + Sbjct: 581 CLPCTEGTTRALRLPPTTTCQQ------QKEELLPAQDIKALFVSEEEKKLTRKEVYIKN 634 Query: 181 ND---VC---AQVHP---------QKVTKFMLCAGRWT--GGKSTCSGDSGGPLVCNG-- 221 D C AQ P + VT LC G + +TC GDSGGPL+ + Sbjct: 635 GDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS 694 Query: 222 --VLQGITSWG 230 + G+ SWG Sbjct: 695 RFIQVGVISWG 705 >3F1S-B nrPDB Length = 283 Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 64/238 (26%), Positives = 88/238 (36%), Gaps = 40/238 (16%) Query: 37 PWQV-LVASRGRAVCGGVLVHPQWVLTAAHCI---RNKSVILLGRHSLFHPEDTGQVFQV 92 PWQV L S G+ CGGV++ +VLT A C RN +V + P + ++ Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP----LMIKI 120 Query: 93 SHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL---- 148 +H H YD D +DL LL L P + A + P ++ A Sbjct: 121 THVHVHMRYD-----------ADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLI 169 Query: 149 -GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC------AGR 201 T SGW + L + ++ + C QV VT C A Sbjct: 170 PRTRGLLSGWARNGTD---LGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMH 226 Query: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 W G S + + G GVL GS+P L TKV Y W K + A Sbjct: 227 WMDG-SVVTREHRGSWFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIMNA 277 >3H5C-B nrPDB Length = 317 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 63/236 (26%), Positives = 87/236 (36%), Gaps = 40/236 (16%) Query: 37 PWQV-LVASRGRAVCGGVLVHPQWVLTAAHCI---RNKSVILLGRHSLFHPEDTGQVFQV 92 PWQV L S G+ CGGV++ +VLT A C RN +V + P + ++ Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP----LMIKI 161 Query: 93 SHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPAL---- 148 +H H YD D +DL LL L P + A + P ++ A Sbjct: 162 THVHVHMRYD-----------ADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLI 210 Query: 149 -GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC------AGR 201 T SGW + L + ++ + C QV VT C A Sbjct: 211 PRTRGLLSGWARNGTD---LGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMH 267 Query: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 W G S + + G GVL GS+P L TKV Y W K + Sbjct: 268 WMDG-SVVTREHRGSWFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >2HNT-C nrPDB Length = 70 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 12/67 (17%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 ILLGRHS 79 + +G+HS Sbjct: 61 VRIGKHS 67 >1P3E-A nrPDB Length = 215 Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust. Identities = 10/24 (41%), Positives = 14/24 (58%) Query: 46 GRAVCGGVLVHPQWVLTAAHCIRN 69 G + C G L+ P +LT HC+ N Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYN 51 >3ARQ-A nrPDB Length = 584 Score = 27.7 bits (60), Expect = 5.5, Method: Compositional matrix adjust. Identities = 22/92 (23%), Positives = 34/92 (36%), Gaps = 11/92 (11%) Query: 89 VFQVSHSFPH-----PLYDMSLLKNRFLRPG--DDSSHDLMLLRLSEPAELTDA----VK 137 +F +++ F P + +L F+RPG D D PA D + Sbjct: 365 IFAMTYDFYGGWNNVPGHQTALYCGSFMRPGQCDGGGVDENGEPYKGPAYTADNGIQLLL 424 Query: 138 VMDLPTQEPALGTTCYASGWGSIEPEEFLTPK 169 +P + LGT Y GW + P+ P Sbjct: 425 AQGVPANKLVLGTAMYGRGWEGVTPDTLTDPN 456 >2EA3-A nrPDB Length = 189 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 15/24 (62%) Query: 211 GDSGGPLVCNGVLQGITSWGSEPC 234 GDSGG L+ QG+TS GS C Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNC 158 >6BXJ-A nrPDB Length = 625 Score = 26.9 bits (58), Expect = 9.2, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 12/91 (13%) Query: 152 CYASGWGSIEPEEFLTPKKLQCVDLHVI--SNDVCAQVHPQKVTKFMLCAGRWTGGKSTC 209 C++S +G I T K +C D + ++C+ H Q LC WTG C Sbjct: 445 CHSSDFGKI------TGKYCECDDFSCVRYKGEMCSG-HGQCSCGDCLCDSDWTGYYCNC 497 Query: 210 SGDSGGPLVCNGVL---QGITSWGSEPCALP 237 + + + NG+L +G GS C P Sbjct: 498 TTRTDTCMSSNGLLCSGRGKCECGSCVCIQP 528 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3QUM-P nrPDB 361 e-100 4NFE-A nrPDB 356 5e-99 1SGF-G nrPDB 336 7e-93 1SPJ-A nrPDB 331 2e-91 1F7Z-A nrPDB 321 3e-88 4AN7-A nrPDB 320 3e-88 4WWY-A nrPDB 320 4e-88 1SGF-A nrPDB 319 8e-88 5FXL-A nrPDB 318 1e-87 1UTJ-A nrPDB 316 5e-87 5C67-A nrPDB 316 5e-87 1AO5-A nrPDB 314 3e-86 1TON-A nrPDB 312 8e-86 1A0J-A nrPDB 312 1e-85 1GVZ-A nrPDB 304 3e-83 1NPM-A nrPDB 300 4e-82 1FXY-A nrPDB 298 2e-81 5MS3-A nrPDB 297 2e-81 2TLD-E nrPDB 292 7e-80 2EEK-A nrPDB 288 1e-78 3T2N-A nrPDB 284 2e-77 3BSQ-A nrPDB 284 3e-77 2PSX-A nrPDB 284 3e-77 4GSO-A nrPDB 281 2e-76 6QHB-A nrPDB 280 3e-76 5ZFH-A nrPDB 279 1e-75 1EUF-A nrPDB 274 2e-74 2AIQ-A nrPDB 270 5e-73 4E7N-A nrPDB 270 6e-73 6I44-A nrPDB 269 6e-73 5TJX-A nrPDB 269 8e-73 1FI8-A nrPDB 268 2e-72 1BQY-A nrPDB 266 7e-72 1OP0-A nrPDB 266 7e-72 1X7A-C nrPDB 265 1e-71 3LC3-A nrPDB 265 1e-71 2BDH-A nrPDB 264 3e-71 2F83-A nrPDB 264 4e-71 3S69-A nrPDB 262 7e-71 5GVT-A nrPDB 262 8e-71 2CGA-A nrPDB 262 1e-70 3K65-B nrPDB 261 2e-70 5UGG-A nrPDB 261 2e-70 5LPF-A nrPDB 261 2e-70 4DUR-A nrPDB 260 3e-70 3NXP-A nrPDB 260 3e-70 1MKW-K nrPDB 259 9e-70 1P57-B nrPDB 259 1e-69 4NZQ-A nrPDB 259 1e-69 3W94-A nrPDB 257 3e-69 3E0N-B nrPDB 257 3e-69 3DFJ-A nrPDB 257 4e-69 1BRU-P nrPDB 256 6e-69 1KIG-H nrPDB 256 9e-69 3S9B-A nrPDB 255 1e-68 1FDP-A nrPDB 254 3e-68 1NN6-A nrPDB 254 4e-68 1IAU-A nrPDB 254 4e-68 2F91-A nrPDB 251 2e-67 2OCV-B nrPDB 250 3e-67 4DGJ-A nrPDB 250 3e-67 1C5M-D nrPDB 250 4e-67 6AOD-C nrPDB 250 4e-67 1YC0-A nrPDB 250 4e-67 4Z6A-H nrPDB 250 5e-67 1VR1-H nrPDB 249 9e-67 1ETT-H nrPDB 249 1e-66 1SC8-U nrPDB 249 1e-66 4MPW-A nrPDB 248 2e-66 3TK9-A nrPDB 248 2e-66 1MZD-A nrPDB 247 2e-66 3G01-A nrPDB 247 3e-66 5FCR-A nrPDB 246 6e-66 1EKB-B nrPDB 246 8e-66 3F6U-H nrPDB 245 1e-65 1LTO-A nrPDB 244 4e-65 4H4F-A nrPDB 243 5e-65 1BDA-A nrPDB 243 5e-65 2V35-A nrPDB 243 8e-65 5LHN-A nrPDB 242 1e-64 1FIZ-A nrPDB 242 1e-64 2R0L-A nrPDB 241 2e-64 1ORF-A nrPDB 240 5e-64 2OQ5-A nrPDB 240 5e-64 1PYT-D nrPDB 240 5e-64 3P8G-A nrPDB 239 1e-63 4XDE-A nrPDB 239 1e-63 1KYN-A nrPDB 239 1e-63 4Q7Y-A nrPDB 239 1e-63 1FIW-A nrPDB 238 2e-63 5TO3-B nrPDB 238 2e-63 5XRF-A nrPDB 237 4e-63 1AZZ-A nrPDB 236 7e-63 1A5I-A nrPDB 235 1e-62 2RDL-A nrPDB 232 2e-61 1FUJ-A nrPDB 231 2e-61 3RP2-A nrPDB 231 2e-61 4BXW-A nrPDB 230 5e-61 4KKD-A nrPDB 230 5e-61 2XXL-A nrPDB 229 1e-60 1ELT-A nrPDB 228 2e-60 1FON-A nrPDB 228 2e-60 4IGD-A nrPDB 227 3e-60 1Q3X-A nrPDB 227 5e-60 2ZKS-A nrPDB 225 1e-59 4FXG-H nrPDB 224 2e-59 4DJZ-B nrPDB 224 3e-59 4IW4-E nrPDB 224 3e-59 1GPZ-A nrPDB 224 4e-59 2QY0-B nrPDB 223 4e-59 1ZJK-A nrPDB 223 5e-59 1MD7-A nrPDB 223 6e-59 5UBM-A nrPDB 222 1e-58 1ELV-A nrPDB 221 3e-58 1YM0-A nrPDB 214 4e-56 4J1Y-A nrPDB 213 4e-56 5KWM-A nrPDB 213 4e-56 2PKA-B nrPDB 212 2e-55 1EQ9-A nrPDB 211 2e-55 2XRC-A nrPDB 211 2e-55 1AE5-A nrPDB 208 2e-54 2OLG-A nrPDB 207 4e-54 5O32-I nrPDB 206 8e-54 1PQ7-A nrPDB 205 1e-53 1PPF-E nrPDB 205 1e-53 4X0L-C nrPDB 204 4e-53 4WJG-C nrPDB 203 7e-53 2B9L-A nrPDB 198 2e-51 2HLC-A nrPDB 198 3e-51 4F4O-C nrPDB 196 7e-51 6BQM-A nrPDB 195 1e-50 1SI5-H nrPDB 193 6e-50 3I77-A nrPDB 193 9e-50 2ASU-B nrPDB 190 5e-49 4LK4-A nrPDB 189 9e-49 3BEU-A nrPDB 187 6e-48 2FMJ-A nrPDB 185 1e-47 3H7T-A nrPDB 178 2e-45 5XW8-A nrPDB 171 2e-43 1M9U-A nrPDB 162 1e-40 3H7O-A nrPDB 158 2e-39 2I6S-A nrPDB 157 4e-39 2WIN-I nrPDB 155 3e-38 3F1S-B nrPDB 155 3e-38 1DLE-A nrPDB 152 1e-37 1AKS-B nrPDB 152 1e-37 2OK5-A nrPDB 151 4e-37 3H5C-B nrPDB 150 5e-37 2JET-B nrPDB 148 3e-36 1RIW-B nrPDB 148 3e-36 3VGC-B nrPDB 148 3e-36 1BBR-H nrPDB 142 1e-34 2KAI-A nrPDB 119 2e-27 2HNT-F nrPDB 116 1e-26 1BBR-E nrPDB 116 1e-26 3RU4-E nrPDB 116 1e-26 2JET-C nrPDB 114 4e-26 1EPT-B nrPDB 98 2e-21 2HNT-C nrPDB 78 4e-15 Sequences not found previously or not previously below threshold: 2HNT-E nrPDB 75 3e-14 1P3E-A nrPDB 39 0.002 2PFE-A nrPDB 37 0.009 3LT3-A nrPDB 37 0.011 2EA3-A nrPDB 36 0.016 2SFA-A nrPDB 34 0.075 2SGA-A nrPDB 34 0.085 2OUA-A nrPDB 33 0.098 1DUE-A nrPDB 33 0.20 5ILB-A nrPDB 31 0.39 4FLN-A nrPDB 31 0.39 1HPG-A nrPDB 31 0.49 2M5T-A nrPDB 31 0.62 5JYK-A nrPDB 31 0.63 5MRT-A nrPDB 30 0.80 5ILA-A nrPDB 30 0.90 3W95-A nrPDB 30 1.1 4FVB-A nrPDB 30 1.1 2HRV-A nrPDB 30 1.1 5MRR-A nrPDB 29 1.4 1GBE-A nrPDB 28 4.1 6HQB-A nrPDB 28 6.2 4FE1-A nrPDB 27 7.2 >3QUM-P nrPDB Length = 237 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 237 >4NFE-A nrPDB Length = 237 Score = 356 bits (914), Expect = 5e-99, Method: Composition-based stats. Identities = 188/237 (79%), Positives = 210/237 (88%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGGWECEKHSQPWQV V S G A CGGVLVHPQWVLTAAHC++ S + LGRH+LF PE Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 DTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHDLMLLRLSEPA++TD VKV+ LPTQ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EPALGTTCYASGWGSIEPEEFL P+ LQCV LH++SND+CA+ + +KVT+FMLCAG WTG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P++YTKVVHYRKWIKDTI ANP Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAANP 237 >1SGF-G nrPDB Length = 237 Score = 336 bits (862), Expect = 7e-93, Method: Composition-based stats. Identities = 128/237 (54%), Positives = 166/237 (70%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG++CEK+SQPW V V + +CGGVL+ P WVLTAAHC + + LG+++LF E Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q VS + PHP ++MSL++ D S+DLMLLRLS+PA++TD VK + LPT+ Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTE 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EP LG+TC ASGWGSI P +F L CV+L ++ N+ CA+ H +KVT MLCAG G Sbjct: 121 EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMDG 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GK TC GDSGGPL+C+GVLQGITSWG PC P+ P +YTK+ + WIKDT+ NP Sbjct: 181 GKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKNP 237 >1SPJ-A nrPDB Length = 238 Score = 331 bits (849), Expect = 2e-91, Method: Composition-based stats. Identities = 145/237 (61%), Positives = 175/237 (73%), Gaps = 1/237 (0%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGGWECE+HSQPWQ + CGG+LVH QWVLTAAHCI + + LGRH+LF E Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPA-ELTDAVKVMDLPT 143 +T Q VS SFPHP ++MSLL+N + +D SHDLMLLRL+EPA +TDAVKV++LPT Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203 +EP +G+TC ASGWGSIEPE F P LQCVDL ++ ND C + H QKVT FMLC G Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK TC GDSGGPL+C+GVLQG+TSWG PC P +PS+ +V+ Y KWI+DTI N Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 237 >1F7Z-A nrPDB Length = 233 Score = 321 bits (822), Expect = 3e-88, Method: Composition-based stats. Identities = 99/236 (41%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ C+++S P+QV + S G CGG L++ QWV++AAHC +++ + LG H++ E Sbjct: 11 IVGGYTCQENSVPYQVSLNS-GYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLE 69 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + HP +D L N D+ML++LS P +L V + LP+ Sbjct: 70 GNEQFVNAAKIIKHPNFDRKTLNN-----------DIMLIKLSSPVKLNARVATVALPSS 118 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 GT C SGWG+ P LQC+D ++ C +P K+T M+C G G Sbjct: 119 CAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEG 178 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C GDSGGP+VCNG LQGI SWG CALP+ P +YTKV +Y WI+DTI AN Sbjct: 179 GKDSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 320 bits (821), Expect = 3e-88, Method: Composition-based stats. Identities = 96/238 (40%), Positives = 135/238 (56%), Gaps = 13/238 (5%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +IVGG+ C +S P+QV + S G CGG L++ QWV++AAHC +++ + LG H++ Sbjct: 7 DKIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV 65 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E Q + HP ++ + L +D+ML++LS PA L V + LP Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTL-----------DNDIMLIKLSSPATLNSRVATVSLP 114 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 A GT C SGWG+ + P LQC+ V+S+ C +P ++T M+C G Sbjct: 115 RSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFL 174 Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK +C GDSGGP+VCNG LQGI SWG CA +P +YTKV +Y WI+ TI AN Sbjct: 175 EGGKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >4WWY-A nrPDB Length = 224 Score = 320 bits (821), Expect = 4e-88, Method: Composition-based stats. Identities = 101/236 (42%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ CE++S P+QV + S G CGG L++ QWV++A HC +++ + LG H++ E Sbjct: 1 IVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + HP YD L N D+ML++LS A + V + LPT Sbjct: 60 GNEQFINAAKIIRHPQYDRKTLNN-----------DIMLIKLSSRAVINAHVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 PA GT C SGWG+ P +LQC+D V+S C +P K+T M C G G Sbjct: 109 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEG 168 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C DSGGP+VCNG LQG+ SWG + CA +P +YTKV +Y KWIK+TI AN Sbjct: 169 GKDSCQRDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >1SGF-A nrPDB Length = 240 Score = 319 bits (818), Expect = 8e-88, Method: Composition-based stats. Identities = 125/245 (51%), Positives = 165/245 (67%), Gaps = 5/245 (2%) Query: 17 AAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLG 76 AAP + S++ +CE +SQPW V V + CGGVL+ WVLTAAHC +K + LG Sbjct: 1 AAPPVQSQV----DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLG 55 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 +++ E + Q VS + PHP ++MSLL +P DD S+DLMLLRLS+PA++TD V Sbjct: 56 KNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVV 115 Query: 137 KVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 K + LPT+EP LG+TC ASGWGS P +F P LQCV+L ++ N+ C + H KVT M Sbjct: 116 KPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAM 175 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 LCAG GG TC DSGGPL+C+G+LQGITSWG EPC P PS+YTK++ + WI++T Sbjct: 176 LCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRET 235 Query: 257 IVANP 261 + NP Sbjct: 236 MANNP 240 >5FXL-A nrPDB Length = 246 Score = 318 bits (816), Expect = 1e-87, Method: Composition-based stats. Identities = 98/257 (38%), Positives = 139/257 (54%), Gaps = 13/257 (5%) Query: 4 PVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63 +FL L + +IVGG+ C ++ P+QV + S G CGG L++ QWV++A Sbjct: 3 TFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSA 61 Query: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLML 123 AHC ++ + LG ++ E Q S S HP Y+ + L N D+ML Sbjct: 62 AHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNN-----------DIML 110 Query: 124 LRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDV 183 ++L A L V + LPT + GT C SGWG+ + P L+C+ ++S+ Sbjct: 111 IKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSS 170 Query: 184 CAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLY 243 C +P ++T M CAG GGK +C GDSGGP+VC+G LQGI SWGS CA +P +Y Sbjct: 171 CKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVY 229 Query: 244 TKVVHYRKWIKDTIVAN 260 TKV +Y WIK TI +N Sbjct: 230 TKVCNYVSWIKQTIASN 246 >1UTJ-A nrPDB Length = 242 Score = 316 bits (811), Expect = 5e-87, Method: Composition-based stats. Identities = 100/258 (38%), Positives = 142/258 (55%), Gaps = 19/258 (7%) Query: 3 VPVVFLTLSVTWIGAAPLILS-RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVL 61 + +VF+ L IGAA +IVGG+EC+ +SQP QV + S G CGG LV+ WV+ Sbjct: 2 ISLVFVLL----IGAAFATEDDKIVGGYECKPYSQPHQVSLNS-GYHFCGGSLVNENWVV 56 Query: 62 TAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDL 121 +AAHC +++ + LG H++ E + Q S HP Y + +D+ Sbjct: 57 SAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYS-----------SYNIDNDI 105 Query: 122 MLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISN 181 ML++LS+PA L V+ + LPT GT C SGWG+ KLQC+++ ++S Sbjct: 106 MLIKLSKPATLNTYVQPVALPTSCAPAGTMCTVSGWGNTMSST-ADSNKLQCLNIPILSY 164 Query: 182 DVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPS 241 C +P +T M CAG GGK +C GDSGGP+VCNG LQG+ SWG CA P P Sbjct: 165 SDCNNSYPGMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPG 223 Query: 242 LYTKVVHYRKWIKDTIVA 259 +Y KV + W+ T+ + Sbjct: 224 VYAKVCIFNDWLTSTMAS 241 >5C67-A nrPDB Length = 224 Score = 316 bits (811), Expect = 5e-87, Method: Composition-based stats. Identities = 99/236 (41%), Positives = 134/236 (56%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ CE++S P+QV + S G CGG L+ QWV++AAHC + + + LG H++ E Sbjct: 1 IVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + HP Y+ D +D+ML++LS PA + V + LPT Sbjct: 60 GNEQFINAAKIIRHPKYN-----------RDTLDNDIMLIKLSSPAVINARVSTISLPTA 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 PA GT C SGWG+ P +L+C+D V++ C +P K+T M C G G Sbjct: 109 PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEG 168 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C D+GGP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDTI AN Sbjct: 169 GKDSCQRDAGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >1AO5-A nrPDB Length = 237 Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats. Identities = 125/236 (52%), Positives = 165/236 (69%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 +VGG+ CEK+SQPWQV V + +CGGVL+ WVLTAAHC ++ + LG++ LF E Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q VS SFPHP ++MSLL + + PG D S DLMLLRLS+PA++TD VK + LPT+ Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EP G+ C ASGWGSI P + P LQCV + ++ N+ CA+V+ QKVT MLCAG G Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK TC DSGGPL+C+G+LQG TS+G PC P P++YT ++ + WIKDT++ N Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >1TON-A nrPDB Length = 235 Score = 312 bits (801), Expect = 8e-86, Method: Composition-based stats. Identities = 126/237 (53%), Positives = 165/237 (69%), Gaps = 2/237 (0%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG++CEK+SQPWQV V + +CGGVL+ P WV+TAAHC N +LLGR++LF E Sbjct: 1 IVGGYKCEKNSQPWQVAVINE--YLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q V SF HP Y ++ N +P D S+DLMLL LSEPA++T VKV+DLPT+ Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EP +G+TC ASGWGS P E + LQCV++H++SN+ C + + VT MLCAG G Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP 261 GK TC+GDSGGPL+C+GVLQGITS G+ PCA P+ P++Y K++ + WIK + NP Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP 235 >1A0J-A nrPDB Length = 223 Score = 312 bits (800), Expect = 1e-85, Method: Composition-based stats. Identities = 95/236 (40%), Positives = 135/236 (57%), Gaps = 13/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+EC K+S +Q + S G CGG L+ WV++AAHC +++ + LG H++ E Sbjct: 1 IVGGYECRKNSASYQASLQS-GYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 T Q HP Y+ L +D+ML++LS+PA L V + LP+ Sbjct: 60 GTEQFIDSVKVIMHPSYNSRNL-----------DNDIMLIKLSKPASLNSYVSTVALPSS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 + GT C SGWG++ P L+C+DL ++S+ C +P ++T M CAG G Sbjct: 109 CASSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEG 168 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK +C GDSGGP+VCNG LQG+ SWG CA +P +YTKV +YR WI T+ +N Sbjct: 169 GKDSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1GVZ-A nrPDB Length = 237 Score = 304 bits (778), Expect = 3e-83, Method: Composition-based stats. Identities = 138/236 (58%), Positives = 171/236 (72%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+GGWECEKHS+PWQV V +G CGGVLVHPQWVLTAAHC+ + I LGRH+L E Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 DT Q QVS SF P +D+SLLK ++LRP DD SHDLMLLRL++PA +TDAVK++DLPTQ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 EP LG+TCY SGWG I LQCV+L + SN+ CA+ +P+K+T+F+LCA Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 S C GDSGG L+C+GV QGITSWG CA ++TKV+ ++KWIK+TI N Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >1NPM-A nrPDB Length = 225 Score = 300 bits (769), Expect = 4e-82, Method: Composition-based stats. Identities = 107/233 (45%), Positives = 141/233 (60%), Gaps = 9/233 (3%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G EC HSQPWQ + R +CGGVLV +WVLTAAHC + K + LG HSL + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q QV+ S HP Y+ S +D SHD+ML+RL A L D VK + L Sbjct: 61 QPEQEIQVAQSIQHPCYNNSN--------PEDHSHDIMLIRLQNSANLGDKVKPVQLANL 112 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 P +G C SGWG++ + P L C ++ + S + C + +P K+T+ M+CAG + Sbjct: 113 CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS-SN 171 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G TC GDSGGPLVC+G+LQGITSWGS+PC PE+P +YTK+ Y WIK T+ Sbjct: 172 GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1FXY-A nrPDB Length = 228 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 91/239 (38%), Positives = 122/239 (51%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPWQVLV-ASRGRAVCGGVLVHPQWVLTAAHCIR--NKSVILLGRHSLF 81 IVGG+ C+ PWQ L+ CGG ++ ++LTAAHC+ + + +G + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E V +V H + + D+ +LRL P V L Sbjct: 61 QEEGGEAVHEVEVVIKHNRF-----------TKETYDFDIAVLRLKTPITFRMNVAPASL 109 Query: 142 PTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGR 201 PT PA GT C SGWG+ P +LQC+D V+S C +P K+T M C G Sbjct: 110 PTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGF 169 Query: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK +C GDSGGP+VCNG LQG+ SWG + CA +P +YTKV +Y KWIK+TI AN Sbjct: 170 LEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >5MS3-A nrPDB Length = 228 Score = 297 bits (762), Expect = 2e-81, Method: Composition-based stats. Identities = 99/236 (41%), Positives = 133/236 (56%), Gaps = 9/236 (3%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC + K + LG HSL + + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q V S PHP Y+ S + +D +HDLMLL+L + A L VK + L Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLADH 112 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 G C SGWG++ P L C ++ + C +P ++T M+CAG + Sbjct: 113 CTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-SK 171 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK I + Sbjct: 172 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 227 >2TLD-E nrPDB Length = 220 Score = 292 bits (749), Expect = 7e-80, Method: Composition-based stats. Identities = 93/236 (39%), Positives = 131/236 (55%), Gaps = 16/236 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+ C ++ P+QV + S G CGG L++ QWV++AAHC ++ + LG ++ E Sbjct: 1 IVGGYTCGANTVPYQVSLNS-GYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q S S HP Y+ + L N D+ML++L A L V + LPT Sbjct: 60 GNEQFISASKSIVHPSYNSNTLNN-----------DIMLIKLKSAASLNSRVASISLPTS 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 + GT C SGWG+ + P L+C+ ++S+ C +P ++T M CAG Sbjct: 109 CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLE-- 166 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 G +C GDSGGP+VC+G LQGI SWGS CA +P +YTKV +Y WIK TI +N Sbjct: 167 GGDSCQGDSGGPVVCSGKLQGIVSWGS-GCA-KNKPGVYTKVCNYVSWIKQTIASN 220 >2EEK-A nrPDB Length = 220 Score = 288 bits (738), Expect = 1e-78, Method: Composition-based stats. Identities = 97/234 (41%), Positives = 131/234 (55%), Gaps = 14/234 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 IVGG+EC KHSQ QV + S G CGG LV WV++AAHC ++ + LG H + E Sbjct: 1 IVGGYECTKHSQAHQVSLNS-GYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 T Q S HP Y + ++D+ML++L++PA L V + LPT+ Sbjct: 60 GTEQYISSSSVIRHPNYS-----------SYNINNDIMLIKLTKPATLNQYVHAVALPTE 108 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 A T C SGWG+ KLQC+ L ++S+ CA +P +T+ M CAG G Sbjct: 109 CAADATMCTVSGWGNT-MSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEG 167 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 GK +C GDSGGP+VCNGVLQG+ SWG CA + P +Y KV W++DT+ Sbjct: 168 GKDSCQGDSGGPVVCNGVLQGVVSWGY-GCAERDHPGVYAKVCVLSGWVRDTMA 220 >3T2N-A nrPDB Length = 372 Score = 284 bits (727), Expect = 2e-77, Method: Composition-based stats. Identities = 89/267 (33%), Positives = 124/267 (46%), Gaps = 23/267 (8%) Query: 7 FLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC 66 FL G L + RIVGG + PWQV + G +CGG L+ WVLTAAHC Sbjct: 100 FLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC 159 Query: 67 IRNKSVI----LLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLM 122 ++ + + ++ G V H Y N +++S+D+ Sbjct: 160 FPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPN-----SEENSNDIA 214 Query: 123 LLRLSEPAELTDAVKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180 L+ LS P LT+ ++ + LP AL G C +GWG+ + LQ + +IS Sbjct: 215 LVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG-QQAGVLQEARVPIIS 273 Query: 181 NDVCA--QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN--------GVLQGITSWG 230 NDVC + ++ M CAG GG C GDSGGP VC L GI SWG Sbjct: 274 NDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG 333 Query: 231 SEPCALPERPSLYTKVVHYRKWIKDTI 257 + CAL ++P +YTKV +R+WI I Sbjct: 334 T-GCALAQKPGVYTKVSDFREWIFQAI 359 >3BSQ-A nrPDB Length = 227 Score = 284 bits (727), Expect = 3e-77, Method: Composition-based stats. Identities = 98/233 (42%), Positives = 131/233 (56%), Gaps = 13/233 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 Q + S SF HP Y N DLML++L+ A L+ VK + LP++ Sbjct: 59 RRAQRIKASKSFRHPGYSTQTHVN-----------DLMLVKLNSQARLSSMVKKVRLPSR 107 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 GTTC SGWG+ + P L CVD+ +IS C +V+ + MLCAG Sbjct: 108 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 167 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 K+ C+GDSGGPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+ Sbjct: 168 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 220 >2PSX-A nrPDB Length = 227 Score = 284 bits (726), Expect = 3e-77, Method: Composition-based stats. Identities = 99/238 (41%), Positives = 140/238 (58%), Gaps = 14/238 (5%) Query: 25 IVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF-H 82 I+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E Q+FQ S PHP Y S+DLML++L+ T V+ +++ Sbjct: 61 YESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPINVS 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 + P+ GT C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG Sbjct: 110 SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD- 168 Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 G+ +C GDSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN Sbjct: 169 KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >4GSO-A nrPDB Length = 232 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 80/236 (33%), Positives = 118/236 (50%), Gaps = 11/236 (4%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC+ + P+ + S G CG L++ +WV+TAAHC + LG HS Sbjct: 1 VLGGDECDINEHPFLAFLYSHGY-FCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q F P +MS + D+ML++L +P + + + LP+ Sbjct: 60 EDEQTRNPKEKFICPNKNMS----------EVLDKDIMLIKLDKPISNSKHIAPLSLPSN 109 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 P++G+ C GWGSI P C +++++ +VC + K LCAG G Sbjct: 110 PPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEG 169 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK TC GDSGGPL+CNG QGI S+G+ C +P +YT V Y WI+ I N Sbjct: 170 GKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >6QHB-A nrPDB Length = 223 Score = 280 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 93/235 (39%), Positives = 134/235 (57%), Gaps = 13/235 (5%) Query: 26 VGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPED 85 V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L E Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQES 61 Query: 86 TGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQE 145 + + V + HP YD + D+MLLRL+ PA+L++ ++ + L Sbjct: 62 SQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPLERDC 110 Query: 146 PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGG 205 A T+C+ GWG +F P +QC +H++S + C +P ++T+ MLCAG G Sbjct: 111 SAQTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYG 168 Query: 206 KSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 K +C GDSGGPLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A Sbjct: 169 KDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >5ZFH-A nrPDB Length = 224 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 90/233 (38%), Positives = 131/233 (56%), Gaps = 13/233 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G++C++ S PWQV + + CGGVLV WVLTAAHC + + LG + + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIG--D 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q + + SF HP Y N D+ML+RL EP +++ V+ + LP Sbjct: 59 QSAQKIKATKSFRHPGYSTKTHVN-----------DIMLVRLDEPVKMSSKVEAVQLPEH 107 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 GT+C SGWG+ + P L C D+ +IS+ C +V+ + K MLCAG Sbjct: 108 CEPPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS 167 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 +TC+GDSGGPLVCN LQG+ SWG+ PC P P +YT+V Y++W+ +T+ Sbjct: 168 KTNTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETM 220 >1EUF-A nrPDB Length = 227 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 88/239 (36%), Positives = 123/239 (51%), Gaps = 20/239 (8%) Query: 25 IVGGWECEKHSQPWQVLV---ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E + HS+P+ + S +CGG LV +VLTAAHC+ + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E T QV V PHP Y+ L N D+MLL+L+ A++TD V ++L Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETLAN-----------DIMLLKLTRKADITDKVSPINL 109 Query: 142 PTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCA 199 P E G C +GWG + + KLQ VDL V S + C + +CA Sbjct: 110 PRSLAEVKPGMMCSVAGWGRLGVN-MPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICA 168 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 G + K++ SGDSGGPLVCNGV QGI S+G P +YT++ + WI T+ Sbjct: 169 GDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGRNDGTT---PDVYTRISSFLSWIHSTMR 224 >2AIQ-A nrPDB Length = 231 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 85/236 (36%), Positives = 119/236 (50%), Gaps = 12/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC + + LV + G +CGG L++ +WVLTA HC R I LG H+L Sbjct: 1 VIGGDECNINEHRFLALVYANGS-LCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 FP Y +N + D+ML+RL+ P + + + LP+ Sbjct: 60 KDALRR-----FPKEKYFCLNTRNDTIW-----DKDIMLIRLNRPVRNSAHIAPLSLPSN 109 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 204 P++G+ C GWG+I P C +++++ VC + + LCAG G Sbjct: 110 PPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-LAATTLCAGILEG 168 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GK TC GDSGGPL+CNG QGI S G PCA P +P +YTKV Y WI+ I N Sbjct: 169 GKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >4E7N-A nrPDB Length = 238 Score = 270 bits (690), Expect = 6e-73, Method: Composition-based stats. Identities = 91/241 (37%), Positives = 126/241 (52%), Gaps = 15/241 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGR--AVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 I+GG EC + + V + + CGG L++ +WVLTAAHC R I LG HS Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 P + Q P + KN L D+ML+RL P + + + LP Sbjct: 61 PNEDEQTR-----VPKEKFFCLSSKNYTLW-----DKDIMLIRLDSPVKNSKHIAPFSLP 110 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ---KVTKFMLCA 199 + P++G+ C GWG I P E P CV+++++ ++C +P+ T LCA Sbjct: 111 SSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCA 170 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 G GGK TC GDSGGPL+CNG QGI SWG +PCA P +P+ YTKV + WI++ I Sbjct: 171 GILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAG 230 Query: 260 N 260 N Sbjct: 231 N 231 >6I44-A nrPDB Length = 627 Score = 269 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 86/254 (33%), Positives = 126/254 (49%), Gaps = 28/254 (11%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHCI-----RNKSV 72 +RIVGG + PWQV + + R +CGG L+ QWVLTAAHC ++ Sbjct: 376 TSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 435 Query: 73 ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 I G L Q+ H Y +S + +HD+ L++L P + Sbjct: 436 IYSGILQLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLQY 484 Query: 133 TDAVKVMDLPTQE--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190 T+ K + LP++ + T C+ +GWG + LQ V++ +++N+ C + + Sbjct: 485 TEFQKPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQ-NILQKVNIPLVTNEECQKRYQD 543 Query: 191 -KVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTK 245 K+T+ M+CAG GGK C GD+GGPLVC L GITSWG E CA E+P +YTK Sbjct: 544 YKITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTK 602 Query: 246 VVHYRKWIKDTIVA 259 V Y WI + + Sbjct: 603 VAEYMDWILEKTQS 616 >5TJX-A nrPDB Length = 263 Score = 269 bits (688), Expect = 8e-73, Method: Composition-based stats. Identities = 89/254 (35%), Positives = 128/254 (50%), Gaps = 28/254 (11%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHCI-----RNKSV 72 +RIVGG E PWQV + + R +CGG L+ QWVLTAAHC ++ Sbjct: 12 TSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 71 Query: 73 ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 I G L Q+ H Y +S + +HD+ L++L P E Sbjct: 72 IYSGILELSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLEY 120 Query: 133 TDAVKVMDLPTQE--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190 T+ K + LP++ + T C+ +GWG + + + LQ V++ +++N+ C + + Sbjct: 121 TEFQKPISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQ-NILQKVNIPLVTNEECQKRYQD 179 Query: 191 -KVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTK 245 K+T+ M+CAG GGK C GDSGGPLVC L GITSWG E CA E+P +YTK Sbjct: 180 YKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWG-EGCARREQPGVYTK 238 Query: 246 VVHYRKWIKDTIVA 259 V Y WI + + Sbjct: 239 VAEYMDWILEKTQS 252 >1FI8-A nrPDB Length = 228 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 116/242 (47%), Gaps = 22/242 (9%) Query: 25 IVGGWECEKHSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG E + HS+P+ + G CGG L+ +VLTAAHC +K + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E Q+ V PHP Y+ + S+D+MLL+L A+ + AVK ++ Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 109 Query: 141 LPTQE--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK-FML 197 LP + G CY +GWG + P LQ V+L V + C K + Sbjct: 110 LPRRNVKVKPGDVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 168 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 CAG +++ GDSGGPLVC V GI S+G + P +TKV + WIK T+ Sbjct: 169 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPR---AFTKVSTFLSWIKKTM 225 Query: 258 VA 259 Sbjct: 226 KK 227 >1BQY-A nrPDB Length = 234 Score = 266 bits (680), Expect = 7e-72, Method: Composition-based stats. Identities = 80/237 (33%), Positives = 119/237 (50%), Gaps = 11/237 (4%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 + GG EC + V++ + +CGG L++ WV+TAAHC N +L G HS Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q F P + D+ D+ML++L ++ + + LP+ Sbjct: 61 EDEQTRDPKEKFFCPNR----------KKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSS 110 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP-QKVTKFMLCAGRWT 203 P++G+ C GWG P + + P C +++++ + VC + ++V LCAG Sbjct: 111 PPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQ 170 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GG+ TC DSGGPL+CNG+ QGI SWG PC P P +YTKV Y WIK I N Sbjct: 171 GGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >1OP0-A nrPDB Length = 234 Score = 266 bits (680), Expect = 7e-72, Method: Composition-based stats. Identities = 80/237 (33%), Positives = 123/237 (51%), Gaps = 11/237 (4%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC+ + + V + CGG L++P+WV+TAAHC + LG HS Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q F P + + + D+ML++L +P + + + LP+ Sbjct: 61 EDEQTRNPKEKFICPNKNNN----------EVLDKDIMLIKLDKPISNSKHIAPLSLPSS 110 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK-FMLCAGRWT 203 P++G+ C GWGSI P + P C +++++ + VC +P+ + + LCAG Sbjct: 111 PPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQ 170 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK TC GDSGGPL+CNG QGI S+G+ PC +P +YT V Y WI+ I N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >1X7A-C nrPDB Length = 235 Score = 265 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 83/242 (34%), Positives = 117/242 (48%), Gaps = 23/242 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRHSLFH 82 IVGG + PWQVL+ + A CGG +++ +WV+TAAHCI K ++ G ++ Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E T Q V + PH Y+ ++ K SHD+ LL L EP L V + + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNK---------YSHDIALLELDEPLTLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 +E G+ Y SGWG + + LQ + + ++ C + + M Sbjct: 112 DKEYTNIFLKFGS-GYVSGWGRV-FNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMF 169 Query: 198 CAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 CAG GGK +C GDSGGP V L GI SWG E CA+ + +YTKV Y WI Sbjct: 170 CAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >3LC3-A nrPDB Length = 235 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 79/242 (32%), Positives = 119/242 (49%), Gaps = 23/242 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRHSLFH 82 +VGG + + PWQV++ + A CGG +V+ +W++TAAHC+ K ++ G H++ Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E T Q V PH Y+ ++ K +HD+ LL L EP L V + + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAINK---------YNHDIALLELDEPLVLNSYVTPICIA 111 Query: 143 TQEPA-----LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 +E G+ Y SGWG + + + LQ + + ++ C + + M Sbjct: 112 DKEYTNIFLKFGS-GYVSGWGRV-FHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMF 169 Query: 198 CAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 CAG GG+ +C GDSGGP V L GI SWG E CA+ + +YTKV Y WI Sbjct: 170 CAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAMKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >2BDH-A nrPDB Length = 223 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 95/236 (40%), Positives = 134/236 (56%), Gaps = 14/236 (5%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL + Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 85 DTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 + G Q+ + S S HP Y+ LL N DLML++L E +D ++ + + + Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESVSESDTIRSISIAS 109 Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203 Q P G +C SGWG + P LQCV++ V+S +VC++++ M CAG Sbjct: 110 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQ 167 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 K +C+GDSGGPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A Sbjct: 168 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >2F83-A nrPDB Length = 625 Score = 264 bits (674), Expect = 4e-71, Method: Composition-based stats. Identities = 85/254 (33%), Positives = 123/254 (48%), Gaps = 28/254 (11%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCIRN-----KSV 72 I RIVGG + PWQV + + R +CGG ++ QW+LTAAHC Sbjct: 384 IKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILR 443 Query: 73 ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 + G + ++ F V H Y M+ +S +D+ LL+L Sbjct: 444 VYSGILNQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVNY 492 Query: 133 TDAVKVMDLPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190 TD+ + + LP++ + T C+ +GWG + + + LQ + +++N+ C + + Sbjct: 493 TDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ-NTLQKAKIPLVTNEECQKRYRG 551 Query: 191 -KVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTK 245 K+T M+CAG GGK C GDSGGPL C L GITSWG E CA ERP +YT Sbjct: 552 HKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTN 610 Query: 246 VVHYRKWIKDTIVA 259 VV Y WI + A Sbjct: 611 VVEYVDWILEKTQA 624 >3S69-A nrPDB Length = 234 Score = 262 bits (671), Expect = 7e-71, Method: Composition-based stats. Identities = 80/237 (33%), Positives = 119/237 (50%), Gaps = 11/237 (4%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 ++GG EC + V + C G L++ +WVLTAAHC + LG HS Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 + Q F P + + D+ML++L ++ + + LP+ Sbjct: 61 EDEQTRNPKEKFICPN----------KKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSS 110 Query: 145 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK-FMLCAGRWT 203 P++G+ C+ GWGSI P + P C ++++ + VC +P+ +T+ LCAG Sbjct: 111 PPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GGK TC GDSGGPL+CNG QGI S+G+ PC +P +YTKV Y WI+ I N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >5GVT-A nrPDB Length = 250 Score = 262 bits (671), Expect = 8e-71, Method: Composition-based stats. Identities = 82/250 (32%), Positives = 118/250 (47%), Gaps = 28/250 (11%) Query: 25 IVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLG 76 IVGG PWQV + + +CGG ++ QWVLTAAHC + I G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 SL ++ H Y +S + ++D+ L++L P T+ Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVS-----------EGNYDIALIKLQTPLNYTEFQ 109 Query: 137 KVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKV-T 193 K + LP++ + T C+ +GWG + E+ T LQ + ++ N+ C + + V Sbjct: 110 KPISLPSKADTNTIYTNCWVTGWGYTK-EQGETQNILQKATIPLVPNEECQKKYRDYVIN 168 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHY 249 K M+CAG GG C GDSGGPLVC L GITSWG E CA ++P +YTKV Y Sbjct: 169 KQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWG-EGCARKDQPGVYTKVSEY 227 Query: 250 RKWIKDTIVA 259 WI + + Sbjct: 228 MDWILEKTQS 237 >2CGA-A nrPDB Length = 245 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 87/247 (35%), Positives = 122/247 (49%), Gaps = 22/247 (8%) Query: 22 LSRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHC-IRNKSVILLGRHS 79 LSRIV G E S PWQV + + G CGG L++ WV+TAAHC + V++ G Sbjct: 13 LSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFD 72 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 + Q +++ F + Y+ + N D+ LL+LS A + V + Sbjct: 73 QGSSSEKIQKLKIAKVFKNSKYNSLTINN-----------DITLLKLSTAASFSQTVSAV 121 Query: 140 DLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 LP+ + A GTTC +GWG TP +LQ L ++SN C + K+ M+ Sbjct: 122 CLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMI 181 Query: 198 CAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 CAG G S+C GDSGGPLVC L GI SWGS C+ P +Y +V W+ Sbjct: 182 CAG--ASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTS-TPGVYARVTALVNWV 238 Query: 254 KDTIVAN 260 + T+ AN Sbjct: 239 QQTLAAN 245 >3K65-B nrPDB Length = 308 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 77/272 (28%), Positives = 117/272 (43%), Gaps = 43/272 (15%) Query: 18 APLILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI-------- 67 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ Sbjct: 43 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 102 Query: 68 --RNKSVILLGRHSLFHPEDT-GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124 N ++ +G+HS E ++ + + HP Y+ ++ D+ L+ Sbjct: 103 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALM 152 Query: 125 RLSEPAELTDAVKVMDLPTQEPAL-----GTTCYASGWGSIEPE-----EFLTPKKLQCV 174 +L +P +D + + LP +E A G +GWG+++ P LQ V Sbjct: 153 KLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVV 212 Query: 175 DLHVISNDVCAQVHPQKVTKFMLCAGR-WTGGK--STCSGDSGGPLVCN------GVLQG 225 +L ++ VC ++T M CAG GK C GD+GGP V G Sbjct: 213 NLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMG 272 Query: 226 ITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 I SWG E C + YT V +KWI+ I Sbjct: 273 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >5UGG-A nrPDB Length = 251 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 91/252 (36%), Positives = 123/252 (48%), Gaps = 34/252 (13%) Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLG 76 R+VGG HS PWQV + +R G CGG L+ P+WVLTAAHC+ + ++LG Sbjct: 20 GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 79 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 H + E Q +VS F P + D+ LL+LS PA +TD V Sbjct: 80 AHQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKV 122 Query: 137 KVMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV--HPQKV 192 LP+ + T C+ +GWG + L+ L VI N VC + +V Sbjct: 123 IPACLPSPNYVVADRTECFITGWGETQ--GTFGAGLLKEAQLPVIENKVCNRYEFLNGRV 180 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVH 248 LCAG GG +C GDSGGPLVC +LQG+TSWG CA P +P +Y +V Sbjct: 181 QSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSR 239 Query: 249 YRKWIKDTIVAN 260 + WI+ + N Sbjct: 240 FVTWIEGVMRNN 251 >5LPF-A nrPDB Length = 234 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 85/233 (36%), Positives = 114/233 (48%), Gaps = 5/233 (2%) Query: 28 GWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTG 87 G C + SQPWQV + + C GVLV WVLTAAHC +G L + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 65 Query: 88 QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPA 147 Q+ + + S HP Y + P HDLMLL+L+ P L V+ + LP + Sbjct: 66 QLRRTTRSVVHPKYHQGS---GPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 148 LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKS 207 G C +GWG+ K L C + ++S C +P VT M+CAG G+ Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQD 181 Query: 208 TCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 C DSGGPLVC+ LQGI SWG PC + P++YT++ Y WI I +N Sbjct: 182 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >4DUR-A nrPDB Length = 791 Score = 260 bits (666), Expect = 3e-70, Method: Composition-based stats. Identities = 91/252 (36%), Positives = 123/252 (48%), Gaps = 34/252 (13%) Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLG 76 R+VGG HS PWQV + +R G CGG L+ P+WVLTAAHC+ + ++LG Sbjct: 560 GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 619 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 H + E Q +VS F P + D+ LL+LS PA +TD V Sbjct: 620 AHQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKV 662 Query: 137 KVMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV--HPQKV 192 LP+ + T C+ +GWG + L+ L VI N VC + +V Sbjct: 663 IPACLPSPNYVVADRTECFITGWGETQ--GTFGAGLLKEAQLPVIENKVCNRYEFLNGRV 720 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVH 248 LCAG GG +C GDSGGPLVC +LQG+TSWG CA P +P +Y +V Sbjct: 721 QSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGL-GCARPNKPGVYVRVSR 779 Query: 249 YRKWIKDTIVAN 260 + WI+ + N Sbjct: 780 FVTWIEGVMRNN 791 >3NXP-A nrPDB Length = 424 Score = 260 bits (666), Expect = 3e-70, Method: Composition-based stats. Identities = 78/272 (28%), Positives = 117/272 (43%), Gaps = 43/272 (15%) Query: 18 APLILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI-------- 67 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ Sbjct: 159 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 218 Query: 68 --RNKSVILLGRHSLFHPEDT-GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124 N ++ +G+HS E ++ + + HP Y+ ++ D+ L+ Sbjct: 219 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALM 268 Query: 125 RLSEPAELTDAVKVMDLPTQEPAL-----GTTCYASGWGSIEPE-----EFLTPKKLQCV 174 +L +P +D + + LP +E A G +GWG+++ P LQ V Sbjct: 269 KLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVV 328 Query: 175 DLHVISNDVCAQVHPQKVTKFMLCAGR-WTGGK--STCSGDSGGPLVCN------GVLQG 225 +L ++ VC ++T M CAG GK C GDSGGP V G Sbjct: 329 NLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMG 388 Query: 226 ITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 I SWG E C + YT V +KWI+ I Sbjct: 389 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 419 >1MKW-K nrPDB Length = 308 Score = 259 bits (662), Expect = 9e-70, Method: Composition-based stats. Identities = 78/272 (28%), Positives = 116/272 (42%), Gaps = 43/272 (15%) Query: 18 APLILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI-------- 67 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ Sbjct: 43 ESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 102 Query: 68 --RNKSVILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124 + ++ +G+HS E ++ + + HP Y+ ++ D+ LL Sbjct: 103 FTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALL 152 Query: 125 RLSEPAELTDAVKVMDLPTQEPAL-----GTTCYASGWGS-----IEPEEFLTPKKLQCV 174 +L P EL+D + + LP ++ A G +GWG+ + P LQ V Sbjct: 153 KLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVV 212 Query: 175 DLHVISNDVCAQVHPQKVTKFMLCAGRWTG---GKSTCSGDSGGPLVCN------GVLQG 225 +L ++ VC ++T M CAG G C GDSGGP V G Sbjct: 213 NLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMG 272 Query: 226 ITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 I SWG E C + YT V +KWI+ I Sbjct: 273 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 303 >1P57-B nrPDB Length = 255 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 84/249 (33%), Positives = 118/249 (47%), Gaps = 23/249 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVI----LLGRHSL 80 IVGG + PWQV + G +CGG L+ WVLTAAHC ++ + + ++ Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 G V H Y N +++S+D+ L+ LS P LT+ ++ + Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPN-----SEENSNDIALVHLSSPLPLTEYIQPVC 115 Query: 141 LPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQKVTKFM 196 LP AL G C +GWG+ + LQ + +ISNDVC + ++ M Sbjct: 116 LPAAGQALVDGKICTVTGWGNTQYYG-QQAGVLQEARVPIISNDVCNGADFYGNQIKPKM 174 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCN--------GVLQGITSWGSEPCALPERPSLYTKVVH 248 CAG GG C GDSGGP VC L GI SWG+ CAL ++P +YTKV Sbjct: 175 FCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSD 233 Query: 249 YRKWIKDTI 257 +R+WI I Sbjct: 234 FREWIFQAI 242 >4NZQ-A nrPDB Length = 557 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 78/272 (28%), Positives = 117/272 (43%), Gaps = 43/272 (15%) Query: 18 APLILSRIVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI-------- 67 I RIV G + E PWQV++ + +CG L+ +WVLTAAHC+ Sbjct: 292 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 351 Query: 68 --RNKSVILLGRHSLFHPEDT-GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124 N ++ +G+HS E ++ + + HP Y+ ++ D+ L+ Sbjct: 352 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALM 401 Query: 125 RLSEPAELTDAVKVMDLPTQEPAL-----GTTCYASGWGSIEPE-----EFLTPKKLQCV 174 +L +P +D + + LP +E A G +GWG+++ P LQ V Sbjct: 402 KLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVV 461 Query: 175 DLHVISNDVCAQVHPQKVTKFMLCAGR-WTGGK--STCSGDSGGPLVCN------GVLQG 225 +L ++ VC ++T M CAG GK C GDSGGP V G Sbjct: 462 NLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMG 521 Query: 226 ITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 I SWG E C + YT V +KWI+ I Sbjct: 522 IVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 552 >3W94-A nrPDB Length = 235 Score = 257 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 79/246 (32%), Positives = 118/246 (47%), Gaps = 27/246 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVI------LLGRH 78 +VGG EK + PW V + RGR CG L+ W+LTAAHC+ K+ +LG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 79 SLFHPEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 + Q+ QV + Y+ + D+ ++ L +P T+ V Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEA-----------DIAMMHLQQPVNFTEWVL 109 Query: 138 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVTK 194 + L +++ G C+ +GWG + E P LQ ++ ++ D C ++ P+ T Sbjct: 110 PVCLASEDQHFPAGRRCFIAGWGR-DAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTS 168 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHYR 250 MLCAG GG +C GDSGGPL+C L G+TS+G C PERP Y +V + Sbjct: 169 SMLCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFT 227 Query: 251 KWIKDT 256 WI +T Sbjct: 228 SWIAET 233 >3E0N-B nrPDB Length = 271 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 87/255 (34%), Positives = 118/255 (46%), Gaps = 32/255 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI-----RNKSVILLGRHS 79 I GG PWQV + G VCGG LV QWVL+AAHC + + LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L + +V + PHP Y + S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY-----------LQEGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 DLPTQEPAL--GTTCYASGWGSIEPE-EFLTPKKLQCVDLHVISNDVCAQVH-------- 188 LP + + G C +GWG + P LTPK LQ +++ +IS + C ++ Sbjct: 110 SLPAAQASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEE 169 Query: 189 PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYT 244 P V + M+CAG GGK C GDSGGPL C L GI SWG + C RP +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTIVA 259 Y WI+ + Sbjct: 229 LASSYASWIQSKVTE 243 >3DFJ-A nrPDB Length = 263 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 87/255 (34%), Positives = 117/255 (45%), Gaps = 32/255 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI-----RNKSVILLGRHS 79 I GG PWQV + G VCGG LV QWVL+AAHC + + LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L + +V + PHP Y + S D+ LL+LS P + ++ + Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY-----------LQEGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 DLPTQEPAL--GTTCYASGWGSIEPE-EFLTPKKLQCVDLHVISNDVCAQVH-------- 188 LP + G C +GWG + P LTPK LQ +++ +IS + C ++ Sbjct: 110 SLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEE 169 Query: 189 PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYT 244 P V + M+CAG GGK C GDSGGPL C L GI SWG + C RP +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWG-DACGARNRPGVYT 228 Query: 245 KVVHYRKWIKDTIVA 259 Y WI+ + Sbjct: 229 LASSYASWIQSKVTE 243 >1BRU-P nrPDB Length = 241 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 89/252 (35%), Positives = 124/252 (49%), Gaps = 27/252 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRG----RAVCGGVLVHPQWVLTAAHCIRNK--SVILLGRH 78 +VGG + +S PWQV + R CGG LV WVLTAAHCI + ++LGRH Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 SL E +VS H ++ + L N +D+ LL+L+ P LTD +++ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSN---------GNDIALLKLASPVSLTDKIQL 111 Query: 139 MDLPTQEPALGT--TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ--VHPQKVTK 194 LP L CY +GWG ++ +P LQ L V+ C++ V Sbjct: 112 GCLPAAGTILPNNYVCYVTGWGRLQTNG-ASPDILQQGQLLVVDYATCSKPGWWGSTVKT 170 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNG-----VLQGITSWGSE-PCALPERPSLYTKVVH 248 M+CAG G S+C+GDSGGPL C G + GI S+GS C +PS++T+V + Sbjct: 171 NMICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSN 229 Query: 249 YRKWIKDTIVAN 260 Y WI I N Sbjct: 230 YIDWINSVIANN 241 >1KIG-H nrPDB Length = 241 Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats. Identities = 70/247 (28%), Positives = 106/247 (42%), Gaps = 25/247 (10%) Query: 25 IVGGWECEKHSQPWQVLV-ASRGRAVCGGVLVHPQWVLTAAHCIR--NKSVILLGRHSLF 81 IVGG +C + PWQ L+ CGG +++ +VLTAAHC+ + + +G + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E +V + H + + D+ +LRL P V L Sbjct: 61 QEEGNEMAHEVEMTVKHSRF-----------VKETYDFDIAVLRLKTPIRFRRNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 P ++ A T T SG+G + L+ L+ +++ + C +T M Sbjct: 110 PEKDWAEATLMTQKTGIVSGFGRTHEKGRLSS-TLKMLEVPYVDRSTCKLSSSFTITPNM 168 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKW 252 CAG T + C GDSGGP V + GI SWG E CA + +YTKV ++ KW Sbjct: 169 FCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKFGVYTKVSNFLKW 227 Query: 253 IKDTIVA 259 I + A Sbjct: 228 IDKIMKA 234 >3S9B-A nrPDB Length = 234 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 81/239 (33%), Positives = 117/239 (48%), Gaps = 15/239 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAV--CGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +VGG EC + P+ V + + + C G L++ +WVLTAAHC R I LG HS Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 + Q+ P Y K + D+ML+RL P + + + LP Sbjct: 61 RNEDEQIR-----VPRGKYFCLNTK-----FPNGLDKDIMLIRLRRPVTYSTHIAPVSLP 110 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP-QKVTKFMLCAGR 201 ++ +G+ C GWG I P C ++ ++ + C ++P LCAG Sbjct: 111 SRSRGVGSRCRIMGWGKISTTT--YPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGI 168 Query: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GG+ TC GDSGGPL+CNG + GI + GSEPC +P++YTKV Y WI+ I N Sbjct: 169 LKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >1FDP-A nrPDB Length = 235 Score = 254 bits (648), Expect = 3e-68, Method: Composition-based stats. Identities = 95/251 (37%), Positives = 132/251 (52%), Gaps = 26/251 (10%) Query: 18 APLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI----RNKSVI 73 A RI+GG E E H++P+ V G +CGGVLV QWVL+AAHC+ K + Sbjct: 1 AAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQV 60 Query: 74 LLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELT 133 LLG HSL PE + +++ V + PHP D HDL+LL+LSE A L Sbjct: 61 LLGAHSLSQPEPSKRLYDVLRAVPHPD-----------SQPDTIDHDLLLLQLSEKATLG 109 Query: 134 DAVKVMDLP----TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ--V 187 AV+ LP ++ A GT C +GWG + P LQ V L V+ C + Sbjct: 110 PAVRP--LPWQRVDRDVAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRTH 166 Query: 188 HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV 247 H +T+ ++CA + + +C GDSGGPLVC GVL+G+ + GS C ++P +YT+V Sbjct: 167 HDGAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVA 224 Query: 248 HYRKWIKDTIV 258 Y WI + Sbjct: 225 SYAAWIDSVLA 235 >1NN6-A nrPDB Length = 228 Score = 254 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 86/244 (35%), Positives = 119/244 (48%), Gaps = 22/244 (9%) Query: 23 SRIVGGWECEKHSQPWQVLV----ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRH 78 I+GG EC+ HS+P+ + ++ CGG L+ +VLTAAHC + LG H Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 ++ EDT Q +V F HP Y+ S L HD+MLL+L E A LT AV Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLH-----------HDIMLLKLKEKASLTLAVGT 109 Query: 139 MDLPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 + P+Q G C +GWG + LQ V L ++ C+ Sbjct: 110 LPFPSQFNFVPPGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACSH-FRDFDHNLQ 167 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 LC G KS GDSGGPL+C GV QGI S+G + + P+++T++ HYR WI Sbjct: 168 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQI 224 Query: 257 IVAN 260 + AN Sbjct: 225 LQAN 228 >1IAU-A nrPDB Length = 227 Score = 254 bits (648), Expect = 4e-68, Method: Composition-based stats. Identities = 82/239 (34%), Positives = 113/239 (47%), Gaps = 21/239 (8%) Query: 25 IVGGWECEKHSQPWQVLV---ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E + HS+P+ + + CGG L+ +VLTAAHC + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E T Q V PHP Y+ + S+D+MLL+L A+ T AV+ + L Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPK-----------NFSNDIMLLQLERKAKRTRAVQPLRL 109 Query: 142 PTQEPA--LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKF-MLC 198 P+ + G TC +GWG P LQ V + V + C LC Sbjct: 110 PSNKAQVKPGQTCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 168 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G K++ GDSGGPLVCN V QGI S+G +P P TKV + WIK T+ Sbjct: 169 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN-GMP--PRACTKVSSFVHWIKKTM 224 >2F91-A nrPDB Length = 237 Score = 251 bits (641), Expect = 2e-67, Method: Composition-based stats. Identities = 74/246 (30%), Positives = 109/246 (44%), Gaps = 29/246 (11%) Query: 25 IVGGWECEKHSQPWQVLVASR----GRAVCGGVLVHPQWVLTAAHCIRNK-------SVI 73 IVGG + P+Q+ CG + + + +TA HC+ I Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 74 LLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELT 133 + G + E + Q+ VS H +D +LL +D+ LL+LS Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLL-----------DNDISLLKLSGSLTFN 109 Query: 134 DAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP-QKV 192 D V + LP Q +GWG+ E TP LQ V + ++S++ C + ++ Sbjct: 110 DNVAPIALPEQGHTATGDVIVTGWGTTS-EGGNTPDVLQKVTVPLVSDEDCRADYGADEI 168 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCNGV----LQGITSWGSEPCALPERPSLYTKVVH 248 M+CAG GGK +C GDSGGPL + L GI SWG CA P P +YT+V + Sbjct: 169 LDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWGY-GCARPGYPGVYTEVSY 227 Query: 249 YRKWIK 254 + WIK Sbjct: 228 HVDWIK 233 >2OCV-B nrPDB Length = 259 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 76/265 (28%), Positives = 114/265 (43%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV GW+ EK PWQV++ + +CG L+ +WVLTAAHCI N + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E + ++ + + HP Y+ ++ D+ LL+L +P Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWR----------ENLDRDIALLKLKKPVP 110 Query: 132 LTDAVKVMDLPTQEPAL-----GTTCYASGWGS-----IEPEEFLTPKKLQCVDLHVISN 181 +D + + LP ++ G +GWG+ + P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVER 170 Query: 182 DVCAQVHPQKVTKFMLCAGR---WTGGKSTCSGDSGGPLVCN------GVLQGITSWGSE 232 VC ++T M CAG T C GDSGGP V GI SWG E Sbjct: 171 PVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWG-E 229 Query: 233 PCALPERPSLYTKVVHYRKWIKDTI 257 C + YT V + WI+ I Sbjct: 230 GCDRKGKYGFYTHVFRLKAWIQKVI 254 >4DGJ-A nrPDB Length = 235 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 121/245 (49%), Gaps = 27/245 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKS------VILLGRH 78 IVGG + ++ + PW V + R +CG LV W+++AAHC+ ++ +LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 79 SLFHPEDTGQV-FQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 + V + +P Y+ +D+ ++ L TD ++ Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRR-----------RKDNDIAMMHLEFKVNYTDYIQ 109 Query: 138 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VTK 194 + LP + G C +GWG++ + T LQ D+ ++SN+ C Q P+ +T+ Sbjct: 110 PISLPEENQVFPPGRNCSIAGWGTV-VYQGTTADILQEADVPLLSNERCQQQMPEYNITE 168 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHYR 250 M+CAG GG +C GDSGGPL+C L G+TS+G E CALP RP +Y +V + Sbjct: 169 NMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYE-CALPNRPGVYARVSRFT 227 Query: 251 KWIKD 255 +WI+ Sbjct: 228 EWIQS 232 >1C5M-D nrPDB Length = 255 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 69/245 (28%), Positives = 105/245 (42%), Gaps = 25/245 (10%) Query: 25 IVGGWECEKHSQPWQVLV-ASRGRAVCGGVLVHPQWVLTAAHCIR--NKSVILLGRHSLF 81 IVGG EC+ PWQ L+ CGG ++ ++LTAAHC+ + + +G + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E V +V H + + D+ +LRL P V L Sbjct: 61 QEEGGEAVHEVEVVIKHNRF-----------TKETYDFDIAVLRLKTPITFRMNVAPACL 109 Query: 142 PTQEPALGT-----TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 P ++ A T T SG+G + +L+ +++ + + C +T+ M Sbjct: 110 PERDWAESTLMTQKTGIVSGFGRTHEKG-RQSTRLKMLEVPYVDRNSCKLSSSFIITQNM 168 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYRKW 252 CAG T + C GDSGGP V + GI SWG E CA + +YTKV + KW Sbjct: 169 FCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKW 227 Query: 253 IKDTI 257 I ++ Sbjct: 228 IDRSM 232 >6AOD-C nrPDB Length = 245 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 82/250 (32%), Positives = 121/250 (48%), Gaps = 28/250 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCIRN-----KSVILLG 76 IVGG + PWQV + + R +CGG ++ QW+LTAAHC + G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 77 RHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 ++ F V H Y M+ +S +D+ LL+L + TD+ Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMA-----------ESGYDIALLKLETTVQYTDSQ 109 Query: 137 KVMDLPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVT 193 + + LP++ + T C+ +GWG + + + LQ + +++N+ C + + K+T Sbjct: 110 RPISLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ-NTLQKAKIPLVTNEECQKRYRGHKIT 168 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHY 249 M+CAG GGK C GD+GGPL C L GITSWG E CA ERP +YT VV Y Sbjct: 169 HKMICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWG-EGCAQRERPGVYTNVVEY 227 Query: 250 RKWIKDTIVA 259 WI + A Sbjct: 228 VDWILEKTQA 237 >1YC0-A nrPDB Length = 283 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 79/267 (29%), Positives = 119/267 (44%), Gaps = 33/267 (12%) Query: 13 TWIGAA----PLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI- 67 G + RI+GG S PW + G + C G LVH WV++AAHC Sbjct: 20 QACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFS 78 Query: 68 ----RNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLML 123 R+ ++LG+H D Q F + P+ LY + + S HDL+L Sbjct: 79 HSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSV----------FNPSDHDLVL 128 Query: 124 LRLSEP----AELTDAVKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLH 177 +RL + A + V+ + LP G C +GWG ++ L+ + Sbjct: 129 IRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVP 188 Query: 178 VISNDVCA--QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG----VLQGITSWGS 231 ++++ C+ +V+ ++ MLCAG + C GDSGGPL C L GI SWG Sbjct: 189 LVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG- 247 Query: 232 EPCALPERPSLYTKVVHYRKWIKDTIV 258 + C +P +YT+V +Y WI D I Sbjct: 248 DGCGRLHKPGVYTRVANYVDWINDRIR 274 >4Z6A-H nrPDB Length = 249 Score = 250 bits (639), Expect = 5e-67, Method: Composition-based stats. Identities = 80/251 (31%), Positives = 120/251 (47%), Gaps = 27/251 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLGRHS 79 IVGG C K PWQVL+ G +CGG L++ WV++AAHC + +LG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L + Q +V+ Y ++HD+ LLRL +P LTD V + Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGT-----------TNHDIALLRLHQPVVLTDHVVPL 109 Query: 140 DLPTQEPALGTTCY-----ASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTK 194 LP + + T + SGWG + + T +L +++ + C +P K+T+ Sbjct: 110 CLPERTFSERTLAFVRFSLVSGWGQL-LDRGATALELMVLNVPRLMTQDCEASYPGKITE 168 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVHYR 250 +M CAG G K +C GDSGGP + L GI SWG + CA +YT+V Y Sbjct: 169 YMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG-QGCATVGHFGVYTRVSQYI 227 Query: 251 KWIKDTIVANP 261 +W++ + + P Sbjct: 228 EWLQKLMRSEP 238 >1VR1-H nrPDB Length = 261 Score = 249 bits (636), Expect = 9e-67, Method: Composition-based stats. Identities = 76/269 (28%), Positives = 116/269 (43%), Gaps = 47/269 (17%) Query: 25 IVGGWECEKHSQPWQVLVASRGR------AVCGGVLVHPQWVLTAAHCI----------R 68 IV G + E PWQV++ ++ R +CG L+ +WVLTAAHC+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 NKSVILLGRHSLFHPEDT-GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127 N ++ +G+HS E ++ + + HP Y+ ++ D+ L++L Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 110 Query: 128 EPAELTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPE-----EFLTPKKLQCVDLH 177 +P +D + + LP +E A G +GWG+++ P LQ V+L Sbjct: 111 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 170 Query: 178 VISNDVCAQVHPQKVTKFMLCAGR-WTGGK--STCSGDSGGPLVCN------GVLQGITS 228 ++ VC ++T M CA GK C GDSGGP V GI S Sbjct: 171 IVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 230 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTI 257 WG E C + YT V +KWI+ I Sbjct: 231 WG-EGCDRDGKYGFYTHVFRLKKWIQKVI 258 >1ETT-H nrPDB Length = 259 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 76/265 (28%), Positives = 114/265 (43%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ + + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E ++ + + HP Y+ ++ D+ LL+L P E Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 LTDAVKVMDLPTQEPAL-----GTTCYASGWGS-----IEPEEFLTPKKLQCVDLHVISN 181 L+D + + LP ++ A G +GWG+ + P LQ V+L ++ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVER 170 Query: 182 DVCAQVHPQKVTKFMLCAGRWTG---GKSTCSGDSGGPLVCN------GVLQGITSWGSE 232 VC ++T M CAG G C GDSGGP V GI SWG E Sbjct: 171 PVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG-E 229 Query: 233 PCALPERPSLYTKVVHYRKWIKDTI 257 C + YT V +KWI+ I Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVI 254 >1SC8-U nrPDB Length = 262 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 79/258 (30%), Positives = 123/258 (47%), Gaps = 32/258 (12%) Query: 24 RIVGGWECEKHSQPWQVLVASRGR-----AVCGGVLVHPQWVLTAAHCI-----RNKSVI 73 +I+GG +QPW + R R VCGG L+ P WV++A HC + ++ Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 74 LLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEP---- 129 LGR L F+V + H Y L + +D+ LL++ Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHH---------NDIALLKIRSKEGRC 125 Query: 130 AELTDAVKVMDLPT--QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ- 186 A+ + ++ + LP+ +P GT+C +G+G ++L P++L+ + +IS+ C Q Sbjct: 126 AQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQP 185 Query: 187 -VHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPS 241 + +VT MLCA +C GDSGGPLVC L GI SWG CAL ++P Sbjct: 186 HYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWG-RGCALKDKPG 244 Query: 242 LYTKVVHYRKWIKDTIVA 259 +YT+V H+ WI+ Sbjct: 245 VYTRVSHFLPWIRSHTKE 262 >4MPW-A nrPDB Length = 245 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 86/262 (32%), Positives = 125/262 (47%), Gaps = 42/262 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCIRNK------SVILL 75 IVGG E + PWQV + G CGG L+HPQWVLTAAHC+ + L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 L++ + Q+ VS HP + + + D+ LL L EP +++ Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQI-----------GADIALLELEEPVKVSSH 106 Query: 136 VKVMDLP--TQEPALGTTCYASGWGSIEPEEFLTPKK-LQCVDLHVISNDVCAQVHP--- 189 V + LP ++ G C+ +GWG ++ +E L P L+ V + ++ N +C + Sbjct: 107 VHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGA 166 Query: 190 ------QKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPER 239 + V MLCAG + +C GDSGGPLVC + G+ SWG E CA P R Sbjct: 167 YTGDDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWG-EGCAQPNR 223 Query: 240 PSLYTKVVHYRKWIKDTIVANP 261 P +YT+V +Y WI + P Sbjct: 224 PGIYTRVTYYLDWIHHYVPKKP 245 >3TK9-A nrPDB Length = 226 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 82/239 (34%), Positives = 118/239 (49%), Gaps = 22/239 (9%) Query: 25 IVGGWECEKHSQPWQVL---VASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E + HS+P+ + + R CGG+LV +VLTAAHC + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E T Q V PHP Y+ + S+++MLL+L A+ T AV+ + L Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPK-----------NFSNNIMLLQLERKAKWTTAVRPLRL 109 Query: 142 PTQEPA--LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ-VHPQKVTKFMLC 198 P+ + G C +GWG + T LQ V L V + C + H +C Sbjct: 110 PSSKAQVKPGQLCSVAGWGYVSMSTLAT--TLQEVLLTVQKDCQCERLFHGNYSRATEIC 167 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 G ++ GDSGGPLVC V QGI S+G++ P P +Y KV H+ WIK T+ Sbjct: 168 VGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKK-GTP--PGVYIKVSHFLPWIKRTM 223 >1MZD-A nrPDB Length = 240 Score = 247 bits (632), Expect = 2e-66, Method: Composition-based stats. Identities = 85/244 (34%), Positives = 125/244 (51%), Gaps = 23/244 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRN-----KSVILLGRHS 79 I+GG E HS+P+ + G VCGGVL+ PQWVLTAAHC ++LG HS Sbjct: 3 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 62 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L E + Q ++ P D S+D+ML++L A+L VK++ Sbjct: 63 LSKNEASKQTLEIKKFIP-----------FSRVTSDPQSNDIMLVKLQTAAKLNKHVKML 111 Query: 140 DLPTQEP-ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA-QVHPQK---VTK 194 + ++ GT C +GWG+ +P+ L+ V + V+S +C Q + +TK Sbjct: 112 HIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITK 171 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV-HYRKWI 253 M+CAG G K +C GD+GGPL+C GV I S G E C + +P +YT + Y+ WI Sbjct: 172 DMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWI 230 Query: 254 KDTI 257 K + Sbjct: 231 KSNL 234 >3G01-A nrPDB Length = 227 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 83/240 (34%), Positives = 123/240 (51%), Gaps = 22/240 (9%) Query: 25 IVGGWECEKHSQPWQV---LVASRGR-AVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG E HS+P+ + G+ CGG LV ++VLTAAHC + LG H++ Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E+T Q+ V+ + PHP Y+ DD S+D+MLL+L A+ T AV+ ++ Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNP-----------DDRSNDIMLLKLVRNAKRTRAVRPLN 109 Query: 141 LPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-AQVHPQKVTKFML 197 LP + G CY +GWG + P+ PK L V L V + VC +Q + Sbjct: 110 LPRRNAHVKPGDECYVAGWGKVTPDG-EFPKTLHEVKLTVQKDQVCESQFQSSYNRANEI 168 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 C G ++ GDSGGPLVC GI S+G + P+ ++T+V+ + WIK T+ Sbjct: 169 CVGDSKIKGASFRGDSGGPLVCKRAAAGIVSYGQTDGSAPQ---VFTRVLSFVSWIKKTM 225 >5FCR-A nrPDB Length = 234 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 83/245 (33%), Positives = 120/245 (48%), Gaps = 23/245 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLGRHS 79 I+GG E H++P+ V G VCGG L+ QWVL+AAHC+ + +LLG HS Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L PE + + V PHP D DL+L +LS+ A L V+ + Sbjct: 61 LSAPEPYKRWYDVQSVVPHPG-----------SRPDSLEDDLILFKLSQNASLGPHVRPL 109 Query: 140 DLP--TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQKVTKF 195 L +E GT C +GWG + P L + + +++ C H VT Sbjct: 110 PLQYEDKEVEPGTLCDVAGWGVV-THAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTIN 168 Query: 196 MLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255 M+CA + + TC GDSG PLVC ++G+ +WGS C ++P +YT+V YR WI++ Sbjct: 169 MMCA--ESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 Query: 256 TIVAN 260 N Sbjct: 227 ITNGN 231 >1EKB-B nrPDB Length = 235 Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats. Identities = 73/245 (29%), Positives = 122/245 (49%), Gaps = 27/245 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKS------VILLGRH 78 IVGG + + + PW V + + VCG LV W+++AAHC+ ++ +LG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 79 SLFHPEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 + + + +P Y+ ++D+ ++ L TD ++ Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKR-----------RKNNDIAMMHLEMKVNYTDYIQ 109 Query: 138 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VTK 194 + LP + G C +GWG++ + T LQ D+ ++SN+ C Q P+ +T+ Sbjct: 110 PICLPEENQVFPPGRICSIAGWGAL-IYQGSTADVLQEADVPLLSNEKCQQQMPEYNITE 168 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHYR 250 M+CAG GG +C GDSGGPL+C +L G+TS+G + CALP RP +Y +V + Sbjct: 169 NMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQ-CALPNRPGVYARVPRFT 227 Query: 251 KWIKD 255 +WI+ Sbjct: 228 EWIQS 232 >3F6U-H nrPDB Length = 240 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 79/250 (31%), Positives = 113/250 (45%), Gaps = 29/250 (11%) Query: 26 VGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRHSLFH 82 + G + PWQV L+ S+ + CG VL+HP WVLTAAHC+ + LG + L Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRR 61 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E + F HP Y S + +D+ LL L++PA L+ + + LP Sbjct: 62 WEKWELDLDIKEVFVHPNYSKST-----------TDNDIALLHLAQPATLSQTIVPICLP 110 Query: 143 TQEPA------LGTTCYASGWGSIEPEEFLTPK----KLQCVDLHVISNDVCAQVHPQKV 192 A G +GWG E + L + + V+ ++ C++V V Sbjct: 111 DSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMV 170 Query: 193 TKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVH 248 ++ MLCAG + C GDSGGP+V + L G+ SWG E C L +YTKV Sbjct: 171 SENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVSR 229 Query: 249 YRKWIKDTIV 258 Y WI I Sbjct: 230 YLDWIHGHIR 239 >1LTO-A nrPDB Length = 245 Score = 244 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 85/262 (32%), Positives = 124/262 (47%), Gaps = 42/262 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRGR---AVCGGVLVHPQWVLTAAHCIRNK------SVILL 75 IVGG E + PWQV + R R CGG L+HPQWVLTAAHC+ + L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 L++ + Q+ VS HP + + + D+ LL L EP ++ Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYII-----------QTGADIALLELEEPVNISSR 106 Query: 136 VKVMDLP--TQEPALGTTCYASGWGSIEPEEFLTPKK-LQCVDLHVISNDVCAQVHP--- 189 V + LP ++ G C+ +GWG ++ +E L P L+ V + ++ N +C + Sbjct: 107 VHTVMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGA 166 Query: 190 ------QKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPER 239 + + MLCAG + +C GDSGGPLVC + G+ SW E CA P R Sbjct: 167 YTGDDVRIIRDDMLCAGN--SQRDSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNR 223 Query: 240 PSLYTKVVHYRKWIKDTIVANP 261 P +YT+V +Y WI + P Sbjct: 224 PGIYTRVTYYLDWIHHYVPKKP 245 >4H4F-A nrPDB Length = 249 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 82/251 (32%), Positives = 126/251 (50%), Gaps = 30/251 (11%) Query: 25 IVGGWECEKHSQPWQVLVAS----RGRAVCGGVLVHPQWVLTAAHCIRN--KSVILLGRH 78 +VGG + HS PWQ+ + R CGG L+ +VLTAAHCI N + +G++ Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 SLFHPEDTGQVF-QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 +L ++ G +F V H ++ LL+N D+ L++L+E EL+D ++ Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRN-----------DIALIKLAEHVELSDTIQ 109 Query: 138 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ--VHPQKVT 193 V LP ++ L CY +GWG + + KLQ V+ + C++ +V Sbjct: 110 VACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHATCSRIDWWGFRVK 168 Query: 194 KFMLCAGRWTGGKSTCSGDSGGPLVCN-----GVLQGITSWGS-EPCALPERPSLYTKVV 247 K M+CAG G S C+GDSGGPL C + GI S+GS C ++P +YT+V Sbjct: 169 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 227 Query: 248 HYRKWIKDTIV 258 Y WI + + Sbjct: 228 AYIDWINEKMQ 238 >1BDA-A nrPDB Length = 265 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 81/264 (30%), Positives = 118/264 (44%), Gaps = 41/264 (15%) Query: 24 RIVGGWECEKHSQPWQVLVASRGR------AVCGGVLVHPQWVLTAAHCIRNKS-----V 72 RI GG + S PWQ + ++ R +CGG+L+ W+L+AAHC + + Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 73 ILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS----E 128 ++LGR P + Q F+V H +D D +D+ LL+L Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFD-----------DDTYDNDIALLQLKSDSSR 121 Query: 129 PAELTDAVKVMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ 186 A+ + V+ + LP + L T C SG+G E ++L+ + + + C Sbjct: 122 CAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTS 181 Query: 187 VH--PQKVTKFMLCAGRWTGGK------STCSGDSGGPLVC----NGVLQGITSWGSEPC 234 H + VT MLCAG G C GDSGGPLVC L GI SWG C Sbjct: 182 QHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGL-GC 240 Query: 235 ALPERPSLYTKVVHYRKWIKDTIV 258 + P +YTKV +Y WI+D + Sbjct: 241 GQKDVPGVYTKVTNYLDWIRDNMR 264 >2V35-A nrPDB Length = 240 Score = 243 bits (620), Expect = 8e-65, Method: Composition-based stats. Identities = 76/251 (30%), Positives = 119/251 (47%), Gaps = 26/251 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRGR----AVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 78 +VGG E +++S P Q+ + R CGG L+ WV+TAAHC+ + +++G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 +L + T Q V HP ++ + + +D+ LLRL++ L V++ Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVA---------AGYDIALLRLAQSVTLNSYVQL 111 Query: 139 MDLPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC--AQVHPQKVTK 194 LP A + CY +GWG L LQ L + +C + V Sbjct: 112 GVLPRAGTILANNSPCYITGWGLTRTNGQLAQ-TLQQAYLPTVDYAICSSSSYWGSTVKN 170 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSE-PCALPERPSLYTKVVHY 249 M+CAG G +S C GDSGGPL C + G+TS+ S C + +P+++T+V Y Sbjct: 171 SMVCAGG-DGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAY 229 Query: 250 RKWIKDTIVAN 260 WI + I +N Sbjct: 230 ISWINNVIASN 240 >5LHN-A nrPDB Length = 247 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 74/256 (28%), Positives = 118/256 (46%), Gaps = 33/256 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGR------AVCGGVLVHPQWVLTAAHCI-----RNKSVI 73 IVGG E +QPW + + + CGG L+ P WV +AAHC + V+ Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 LLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS----EP 129 LG+ F+V H Y L +D+ LL++ + Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLA---------YHNDIALLKIRTSTGQC 111 Query: 130 AELTDAVKVMDLPTQ--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ- 186 A+ + +++ + LP + + G+ C +G+G ++L PK L+ + ++S++ C Q Sbjct: 112 AQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQP 171 Query: 187 -VHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPS 241 + ++ MLCA +C GDSGGPL+CN L GI SWG CA +P Sbjct: 172 HYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG-RGCAEKNKPG 230 Query: 242 LYTKVVHYRKWIKDTI 257 +YT+V H+ WI+ I Sbjct: 231 VYTRVSHFLDWIQSHI 246 >1FIZ-A nrPDB Length = 263 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 77/263 (29%), Positives = 112/263 (42%), Gaps = 39/263 (14%) Query: 25 IVGGWECEKHSQPWQVLVA------SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRH 78 +VGG E + PW V + +R CGG+L++ WVLTAAHC +NK + R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 SLFHPE----------DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSE 128 E Q V H Y L +D+ L++++ Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGL-----------EINDIALIKITP 109 Query: 129 PAELTDAVKVMDLP---TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185 P + LP P TC+ +GWG ++ + T LQ + +I ++C Sbjct: 110 PVPCGPFIGPGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCN 169 Query: 186 --QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG------VLQGITSWGSEPCALP 237 + + ++ +CAG G TC GDSGGPL+C V+ GITSWG CA Sbjct: 170 STRWYNGRIRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV-GCARA 228 Query: 238 ERPSLYTKVVHYRKWIKDTIVAN 260 +RP +YT Y WI I +N Sbjct: 229 KRPGVYTSTWPYLNWIASKIGSN 251 >2R0L-A nrPDB Length = 248 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 77/251 (30%), Positives = 116/251 (46%), Gaps = 29/251 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI-----RNKSVILLGRHS 79 I+GG S PW + G + C G LVH WV++AAHC R+ ++LG+H Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEP----AELTDA 135 D Q F + P+ LY + + S HDL+L+RL + A + Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSV----------FNPSDHDLVLIRLKKKGDRCATRSQF 109 Query: 136 VKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQK 191 V+ + LP G C +GWG ++ L+ + ++++ C+ +V+ Sbjct: 110 VQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD 169 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG----VLQGITSWGSEPCALPERPSLYTKVV 247 ++ MLCAG + C GDSGGPL C L GI SWG + C +P +YT+V Sbjct: 170 ISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWG-DGCGRLHKPGVYTRVA 228 Query: 248 HYRKWIKDTIV 258 +Y WI D I Sbjct: 229 NYVDWINDRIR 239 >1ORF-A nrPDB Length = 234 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 84/244 (34%), Positives = 125/244 (51%), Gaps = 21/244 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHC-IRNKSVILLGRHSLFHP 83 I+GG E HS+P+ VL++ + +C G L+ WVLTAAHC + +S ++LG HS+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 E T Q+ V FP+P YD + DL LL+L+E A++ V ++ LP Sbjct: 61 EPTKQIMLVKKEFPYPCYDPAT-----------REGDLKLLQLTEKAKINKYVTILHLPK 109 Query: 144 Q--EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV----HPQKVTKFML 197 + + GT C +GWG L+ V++ +I VC + M+ Sbjct: 110 KGDDVKPGTMCQVAGWGRTHNSASW-SDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMV 168 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEP-CALPERPSLYTKVV-HYRKWIKD 255 CAG GG+ +C+GDSG PL+C GV +G+TS+G E C P P +Y + + WI Sbjct: 169 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 228 Query: 256 TIVA 259 TI Sbjct: 229 TIKG 232 >2OQ5-A nrPDB Length = 232 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 72/241 (29%), Positives = 105/241 (43%), Gaps = 23/241 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP- 83 IVGG E E+ PWQ + G CG L++ W+++AAHC S Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP- 142 + + + H Y +D+ L LS P T+AV + LP Sbjct: 61 KPSKMKRGLRRIIVHEKY-----------KHPSHDYDISLAELSSPVPYTNAVHRVCLPD 109 Query: 143 -TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQKVTKFMLCA 199 + E G + +G+G+++ + + + L+ + +I C Q + +T MLCA Sbjct: 110 ASYEFQPGDVMFVTGFGALKNDGY-SQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCA 168 Query: 200 GRWTGGKSTCSGDSGGPLVCN-----GVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254 G G C GDSGGPLV + L GI SWG E CA P +P +YT+V R WI Sbjct: 169 GSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTALRDWIT 227 Query: 255 D 255 Sbjct: 228 S 228 >1PYT-D nrPDB Length = 251 Score = 240 bits (612), Expect = 5e-64, Method: Composition-based stats. Identities = 84/263 (31%), Positives = 131/263 (49%), Gaps = 32/263 (12%) Query: 15 IGA---APLILSRIVGGWECEKHSQPWQVLVAS----RGRAVCGGVLVHPQWVLTAAHCI 67 GA P + +R+VGG + HS PWQ+ + R CGG L+ P VLTAAHCI Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 68 RN--KSVILLGRHSLFHPEDTGQVF-QVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124 N + LG+++L ++ G ++ V F H ++ L++N D+ L+ Sbjct: 61 SNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRN-----------DIALI 109 Query: 125 RLSEPAELTDAVKVMDLPTQEPALGT--TCYASGWGSIEPEEFLTPKKLQCVDLHVISND 182 +L+E EL D ++V LP++ L C+ +GWG + + + LQ V+ Sbjct: 110 KLAETVELGDTIQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAE-LQQGLQPVVDYA 168 Query: 183 VCAQ--VHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSE-PCA 235 C+Q V + M+CAG G S C+GDSGGPL C ++GI S+GS C Sbjct: 169 TCSQRDWWGTTVKETMVCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCN 227 Query: 236 LPERPSLYTKVVHYRKWIKDTIV 258 ++P+++T+V Y WI + Sbjct: 228 TFKKPTVFTRVSAYIDWINQKLQ 250 >3P8G-A nrPDB Length = 241 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 73/251 (29%), Positives = 117/251 (46%), Gaps = 32/251 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGR-AVCGGVLVHPQWVLTAAHCIRN----------KSVI 73 +VGG + ++ PWQV + + G+ +CG L+ P W+++AAHC + + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 74 LLGRHSLFHPEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 LG H G Q ++ HP ++ +D+ LL L +PAE Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFT-----------FDYDIALLELEKPAEY 109 Query: 133 TDAVKVMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190 + V+ + LP G + +GWG + LQ ++ VI C + PQ Sbjct: 110 SSMVRPICLPDASHVFPAGKAIWVTGWGHTQ-YGGTGALILQKGEIRVIQQTTCENLLPQ 168 Query: 191 KVTKFMLCAGRWTGGKSTCSGDSGGPLV---CNG--VLQGITSWGSEPCALPERPSLYTK 245 ++T M+C G +GG +C GDSGGPL +G G+ SWG + CA +P +YT+ Sbjct: 169 QITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG-DGCAQRNKPGVYTR 227 Query: 246 VVHYRKWIKDT 256 + +R WIK+ Sbjct: 228 LPLFRDWIKEN 238 >4XDE-A nrPDB Length = 257 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 82/256 (32%), Positives = 117/256 (45%), Gaps = 34/256 (13%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK-----SVILLGRHS 79 +VGG + + P+ + G + C G L+ P WVLTAAHC++++ ++LG+ Sbjct: 3 VVGGLVALRGAHPYIAALYW-GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE-----LTD 134 H + Q V H + + HDL LLRL E A+ L+ Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQ-----------HDLALLRLQEDADGSCALLSP 110 Query: 135 AVKVMDLPT--QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQ 190 V+ + LP+ P+ T C +GWG LQ + +S + C+ VH Sbjct: 111 YVQPVSLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS 170 Query: 191 KVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPERPSLY 243 + MLCAG GG C GDSGGPLVC LQGI SWGS C +P +Y Sbjct: 171 SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVY 229 Query: 244 TKVVHYRKWIKDTIVA 259 T V +Y WI++ V+ Sbjct: 230 TDVAYYLAWIREHTVS 245 >1KYN-A nrPDB Length = 235 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 74/240 (30%), Positives = 114/240 (47%), Gaps = 21/240 (8%) Query: 25 IVGGWECEKHSQPWQVLVASR---GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 I+GG E HS+P+ + + G++ CGG LV +VLTAAHC + + LG H++ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 E+T Q + HP Y+ ++N D+MLL+LS V + L Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQN-----------DIMLLQLSRRVRRNRNVNPVAL 109 Query: 142 PTQEPA--LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCA 199 P + GT C +GWG + L+ V L V + C ++ + +C Sbjct: 110 PRAQEGLRPGTLCTVAGWGRVSMRRGT--DTLREVQLRVQRDRQCLRIFGSYDPRRQICV 167 Query: 200 GRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 G K+ GDSGGPL+CN V GI S+G +P P ++T+V + WI+ T+ + Sbjct: 168 GDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSS-GVP--PEVFTRVSSFLPWIRTTMRS 224 >4Q7Y-A nrPDB Length = 250 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 83/242 (34%), Positives = 116/242 (47%), Gaps = 20/242 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV----ILLGRHSL 80 I+GG E HS+P+ V G+ CGG L+ +WV++AAHC ++ + ++LG H L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E T QVF + HP Y N D+ LLRL+ A L AV ++ Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHAN-----------DICLLRLNGSAVLGPAVGLLR 109 Query: 141 LP---TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 LP + P GT C +GWG + E L P L + V+ DVC +T ML Sbjct: 110 LPGRRARPPTAGTRCRVAGWGFVSDFEELPPG-LMEAKVRVLDPDVCNSSWKGHLTLTML 168 Query: 198 CAG-RWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 C + + CS DSGGPLVC G+ S+ C P+ P +YT+V + WI D Sbjct: 169 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 228 Query: 257 IV 258 + Sbjct: 229 VR 230 >1FIW-A nrPDB Length = 290 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 76/262 (29%), Positives = 111/262 (42%), Gaps = 39/262 (14%) Query: 25 IVGGWECEKHSQPWQVLVA------SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRH 78 I+GG + + PW V + +R VCGG L++ QW+LTAAHC R K + R Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 SLFHPE----------DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSE 128 E Q V H Y S ++D+ L++++ Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSAS-----------SEANDIALMKITP 109 Query: 129 PAELTDAVKVMDLP---TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185 P + LP P + TC+ +GWG ++ T LQ + +I +C Sbjct: 110 PVTCGHFIGPGCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCN 169 Query: 186 --QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG------VLQGITSWGSEPCALP 237 + + ++ +CAG G TC GDSGGPL+C V+ GITSWG CA Sbjct: 170 STRWYNGRIRSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARA 228 Query: 238 ERPSLYTKVVHYRKWIKDTIVA 259 +RP +YT Y WI I + Sbjct: 229 KRPGVYTSTWSYLNWIASKIGS 250 >5TO3-B nrPDB Length = 409 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 74/265 (27%), Positives = 114/265 (43%), Gaps = 43/265 (16%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 ILLGRHSLFHPEDT-GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E ++ + + HP Y+ ++ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 LTDAVKVMDLPTQEPAL-----GTTCYASGWGSIEPE-----EFLTPKKLQCVDLHVISN 181 +D + + LP +E A G +GWG+++ P LQ V+L ++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 170 Query: 182 DVCAQVHPQKVTKFMLCAGR-WTGGK--STCSGDSGGPLVCN------GVLQGITSWGSE 232 VC ++T M CAG GK C GDSGGP V GI S G+ Sbjct: 171 PVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA- 229 Query: 233 PCALPERPSLYTKVVHYRKWIKDTI 257 C + YT V +KWI+ I Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVI 254 >5XRF-A nrPDB Length = 242 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 74/239 (30%), Positives = 117/239 (48%), Gaps = 13/239 (5%) Query: 25 IVGGWECEKHSQPWQVLVASR--GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 ++GG EC+ + + + C G L+H +WVL AAHC + I LG H+ Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 D Q Y + R D++LL+L++P + + + LP Sbjct: 67 QFDDEQRR----------YAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLP 116 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-KVTKFMLCAGR 201 + P++G+ C GWG + + + P C ++++++ C +P T +LCAG Sbjct: 117 SSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGV 176 Query: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 GG TC+ DSGGPL+C+G QGI +G PCA P +P LYT+V +Y WI++ I Sbjct: 177 LEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAGK 235 >1AZZ-A nrPDB Length = 226 Score = 236 bits (603), Expect = 7e-63, Method: Composition-based stats. Identities = 78/232 (33%), Positives = 117/232 (50%), Gaps = 15/232 (6%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK--SVILLGRHSLFH 82 IVGG E +S P Q + CGG L+ P+W+LTAAHC+ ++LG H++ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E T Q + H Y+ ++ S+D+ ++RL P LT A+ + LP Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVI-----------SNDIAVIRLPVPVTLTAAIATVGLP 109 Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202 + + +GT +GWG L+ VD+ ++SN C V+ VT +C Sbjct: 110 STDVGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNICI-DS 167 Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254 TGGK TC+GDSGGPL NG+ GITS+G+ P +T+V ++ WI+ Sbjct: 168 TGGKGTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >1A5I-A nrPDB Length = 265 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 81/260 (31%), Positives = 121/260 (46%), Gaps = 41/260 (15%) Query: 27 GGWECEKHSQPWQVLVASRGR------AVCGGVLVHPQWVLTAAHCIRNKS-----VILL 75 GG + S PWQ + ++ R +CGG+L+ WVLTAAHC + ++L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS----EPAE 131 GR P + Q F+V H +D D ++D+ LL+L + A+ Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFD-----------DDTYNNDIALLQLKSDSPQCAQ 124 Query: 132 LTDAVKVMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ--V 187 +D+V+ + LP L T C SG+G + ++L+ + + + CA + Sbjct: 125 ESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFL 184 Query: 188 HPQKVTKFMLCAGRWTGGK------STCSGDSGGPLVC----NGVLQGITSWGSEPCALP 237 + VT MLCAG G+ C GDSGGPLVC + L GI SWG C Sbjct: 185 FNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEK 243 Query: 238 ERPSLYTKVVHYRKWIKDTI 257 + P +YTKV +Y WI+D + Sbjct: 244 DVPGVYTKVTNYLGWIRDNM 263 >2RDL-A nrPDB Length = 226 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 79/242 (32%), Positives = 111/242 (45%), Gaps = 22/242 (9%) Query: 25 IVGGWECEKHSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG EC H++P+ + + C G L+ +V+TAAHC +LLG H+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK--V 138 EDT Q +V FPHP YD L+ N D+MLL+L E A LT V Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLN-----------DIMLLKLKEKANLTLGVGTLP 109 Query: 139 MDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 198 + + G C A GWG E LQ V + ++ C + LC Sbjct: 110 ISAKSNSIPPGRVCRAVGWGRTNVNEP-PSDTLQEVKMRILDPQACKHFEDFH-QEPQLC 167 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 G ++ GDSGGPL+C G+ QGI S+ + PS++T++ HYR WI + Sbjct: 168 VGNPKKIRNVYKGDSGGPLLCAGIAQGIASYVLR---NAKPPSVFTRISHYRPWINKILR 224 Query: 259 AN 260 N Sbjct: 225 EN 226 >1FUJ-A nrPDB Length = 221 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 81/243 (33%), Positives = 124/243 (51%), Gaps = 31/243 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCIRNKSV----ILLGR 77 IVGG E + HS+P+ + RG CGG L+HP +VLTAAHC+R+ ++LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 78 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 H++ E T Q F V+ F + YD ++ +D++L++LS PA L+ +V Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYD-----------AENKLNDILLIQLSSPANLSASVA 108 Query: 138 VMDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKF 195 + LP Q+ + GT C A GWG + + LQ +++ V++ C Sbjct: 109 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQ-VLQELNVTVVT-FFC--------RPH 158 Query: 196 MLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255 +C C GDSGGPL+C+G++QGI S+ CA P +T+V Y WI+ Sbjct: 159 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 218 Query: 256 TIV 258 T+ Sbjct: 219 TLR 221 >3RP2-A nrPDB Length = 224 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 84/240 (35%), Positives = 121/240 (50%), Gaps = 22/240 (9%) Query: 25 IVGGWECEKHSQPWQVLV---ASRG-RAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+GG E HS+P+ + +G R +CGG L+ Q+VLTAAHC + ++LG H + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E T Q +V H Y+ + HD+MLL+L + ELT AV V+ Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSV-----------PNLHDIMLLKLEKKVELTPAVNVVP 109 Query: 141 LPTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 198 LP+ G C+A+GWG + T L+ V+L ++ C + KF +C Sbjct: 110 LPSPSDFIHPGAMCWAAGWGKTGVRDP-TSYTLREVELRIMDEKACVD-YRYYEYKFQVC 167 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 G T ++ GDSGGPL+C GV GI S+G P A P P+++T+V Y WI I Sbjct: 168 VGSPTTLRAAFMGDSGGPLLCAGVAHGIVSYG-HPDAKP--PAIFTRVSTYVPWINAVIN 224 >4BXW-A nrPDB Length = 423 Score = 230 bits (587), Expect = 5e-61, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 106/252 (42%), Gaps = 17/252 (6%) Query: 19 PLILSRIVGGWECEKHSQPWQVLVA-SRGRAVCGGVLVHPQWVLTAAHCIRNKSV--ILL 75 P RIV G +C+ PWQ + + CGG ++ P +VLTAAHCI +++ Sbjct: 164 PSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVV 223 Query: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 G E TG + V + H + +F D +D+ ++++ P + ++ Sbjct: 224 GEIDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFDLAAYD--YDIAIIQMKTPIQFSEN 280 Query: 136 VKVMDLPTQEPALG-----TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190 V LPT + A SG+G I + K L+ + + + C Sbjct: 281 VVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPK-SKTLKVLKVPYVDRHTCMVSSET 339 Query: 191 KVTKFMLCAGRWTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKV 246 +T M CAG T + C GDSGGP + GI S G E CA + YTK+ Sbjct: 340 PITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSG-EGCARNGKYGNYTKL 398 Query: 247 VHYRKWIKDTIV 258 + WIK + Sbjct: 399 SKFIPWIKRIMR 410 >4KKD-A nrPDB Length = 433 Score = 230 bits (586), Expect = 5e-61, Method: Composition-based stats. Identities = 76/284 (26%), Positives = 115/284 (40%), Gaps = 57/284 (20%) Query: 19 PLILSRIVGGWECEKHSQPWQVLVASRGRA-------VCGGVLVHPQWVLTAAHCIRNKS 71 P ++ RI+GG E PWQ L+ + G L+ W+LTAAH +R++ Sbjct: 149 PSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQR 208 Query: 72 -------------VILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS 118 + LG H + + + HP +++ + + Sbjct: 209 RDTTVIPVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNI-----------QNYN 256 Query: 119 HDLMLLRLSEPAELTDAVKVMDLPT---QEPALGTTCYASGWGSIEPE----------EF 165 HD+ L++L EP L V + LP + PA +GWG P Sbjct: 257 HDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTR 316 Query: 166 LTPKKLQCVDLHVISNDVCAQVHPQK-----VTKFMLCAGRWTGGKSTCSGDSGGPLV-- 218 LQ V L V+ + C + + VT+ M CAG + GGK TC GDSG V Sbjct: 317 TLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIF 376 Query: 219 ----CNGVLQGITSW-GSEPCALPERPSLYTKVVHYRKWIKDTI 257 V+QG+ SW G E C + +YTKV +Y W+ + + Sbjct: 377 DDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >2XXL-A nrPDB Length = 408 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 74/272 (27%), Positives = 118/272 (43%), Gaps = 31/272 (11%) Query: 14 WIGAAPLILSRIVGGWECEKHSQPWQVLVAS----RGRAVCGGVLVHPQWVLTAAHCI-- 67 G + R+ G+E + S+PW L+ R +CGG ++ +++LTAAHC+ Sbjct: 110 DCGN--FLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHG 167 Query: 68 --RNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSS--HDLML 123 + I LG H + ED Q + P P+ ++ + K+ D HD+ L Sbjct: 168 LQNDLYEIRLGEHRISTEEDCRQQGRKKKCAP-PVVNVGIEKHLIHEKYDARHIMHDIAL 226 Query: 124 LRLSEPAELTDAVKVMDLP-----TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHV 178 L+L+ +K + LP ++ +T + +GWG+ E + L ++ + Sbjct: 227 LKLNRSVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTT--ENGSSSDVLLQANVPL 284 Query: 179 ISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC----------NGVLQGITS 228 C+Q + + V LC G + +C GDSGGPL V GI S Sbjct: 285 QPRSACSQAYRRAVPLSQLCVGGGDL-QDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVS 343 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 G C P LYT V Y +WI DT+ +N Sbjct: 344 QGVVTCGQISLPGLYTNVGEYVQWITDTMASN 375 >1ELT-A nrPDB Length = 236 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 74/248 (29%), Positives = 115/248 (46%), Gaps = 27/248 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRG----RAVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRH 78 +VGG + +S PWQ+ + + CGG L+ WV+TAAHC+ + ++LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 +L E Q+ V+ F H ++ + +D+ LLRL+ A L AV++ Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVA---------GGYDIALLRLNTQASLNSAVQL 111 Query: 139 MDLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV--HPQKVTK 194 LP L CY +GWG L L+ L + + C+ V Sbjct: 112 AALPPSNQILPNNNPCYITGWGKTSTGGPL-SDSLKQAWLPSVDHATCSSSGWWGSTVKT 170 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWG-SEPCALPERPSLYTKVVHY 249 M+CAG G S C+GDSGGPL C + G+TS+ S C ++P+++T+V Y Sbjct: 171 TMVCAGG--GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAY 228 Query: 250 RKWIKDTI 257 W+ + Sbjct: 229 ISWMNGIM 236 >1FON-A nrPDB Length = 240 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 81/252 (32%), Positives = 124/252 (49%), Gaps = 30/252 (11%) Query: 27 GGWECEKHSQPWQVLVASRG----RAVCGGVLVHPQWVLTAAHCIRNK--SVILLGRHSL 80 G + +S WQV + CGG L+ P WV+TA HCI ++LG + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 81 FHPEDTGQVFQVS--HSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 E + QV ++ F HPL++ + + +D+ L++LS A+L D V++ Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVA---------CGNDIALVKLSRSAQLGDKVQL 111 Query: 139 MDLPTQEPALGT--TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV--HPQKVTK 194 +LP L CY SGWG + L P KLQ L + + C+Q V K Sbjct: 112 ANLPPAGDILPNEAPCYISGWGRLYTGGPL-PDKLQQALLPTVDYEHCSQWDWWGITVKK 170 Query: 195 FMLCAGRWTGGKSTCSGDSGGPLVC-----NGVLQGITSWGSE-PCALPERPSLYTKVVH 248 M+CAG T +S C+GDSGGPL C + + G+TS+ S C ++P+++T+V Sbjct: 171 TMVCAGGDT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSA 228 Query: 249 YRKWIKDTIVAN 260 + WI +TI +N Sbjct: 229 FIDWIDETIASN 240 >4IGD-A nrPDB Length = 406 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 73/264 (27%), Positives = 120/264 (45%), Gaps = 42/264 (15%) Query: 21 ILSRIVGGWECEKHSQPWQVLVAS-RGRAVCGGVLVHPQWVLTAAHCIR----------- 68 ++++I G +K + PW +++ G+ CGG L+ W++TAAHC+ Sbjct: 152 LMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLR 211 Query: 69 -------NKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDL 121 + I+LG+H ++ Q V H+ HP YD + +D+ Sbjct: 212 DSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNT-----------FENDV 260 Query: 122 MLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISN 181 L+ L E L V + LP G SGWG + F P+ L +++ ++ + Sbjct: 261 ALVELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDH 318 Query: 182 DVCAQVH---PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSE 232 C + + +KVT+ M+CAG GGK C+GDSGGP+V L G SWG + Sbjct: 319 STCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD 378 Query: 233 PCALPERPSLYTKVVHYRKWIKDT 256 C +R +Y+ + H + WI+ Sbjct: 379 -CGKKDRYGVYSYIHHNKDWIQRV 401 >1Q3X-A nrPDB Length = 328 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 72/255 (28%), Positives = 111/255 (43%), Gaps = 34/255 (13%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 RI GG + + PWQVL+ G G L++ WVLTAAH + + +H Sbjct: 85 GRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQ------KHDASA 136 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDD----SSHDLMLLRLSEPAELTDAVKV 138 + + + P Y + + F+ G +D+ L++L+ + + Sbjct: 137 LD----IRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 192 Query: 139 MDLPTQEPA----LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH------ 188 + LP +E ASGWG + + L VD+ ++ + C + Sbjct: 193 ICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTAAYEKPPYP 250 Query: 189 PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCALPERPSL 242 VT MLCAG +GGK +C GDSGG LV + GI SWGS C + + Sbjct: 251 RGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGV 310 Query: 243 YTKVVHYRKWIKDTI 257 YTKV++Y WI++ I Sbjct: 311 YTKVINYIPWIENII 325 >2ZKS-A nrPDB Length = 240 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 23/241 (9%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKS---VILLGRHSLF 81 I+GG E HS+P+ + G +CGGVLVHP+WVLTAAHC+ + ++LG H+L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 P G F + + HP Y +P +DL LL+L + + ++ + L Sbjct: 61 SP---GLTFHIKAAIQHPRY----------KPVPALENDLALLQLDGKVKPSRTIRPLAL 107 Query: 142 PTQEP--ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA--QVHPQKVTKFML 197 P++ A GT C +GWG L + L+ +DL V+ +C + ++ M+ Sbjct: 108 PSKRQVVAAGTRCSMAGWGLTHQGGRL-SRVLRELDLQVLDTRMCNNSRFWNGSLSPSMV 166 Query: 198 CAGRWTGGKSTCSGDSGGPLVC--NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255 C + ++ C GDSGGPLVC VL G+ S+ S C +P + T V Y WI+ Sbjct: 167 CLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRK 226 Query: 256 T 256 Sbjct: 227 V 227 >4FXG-H nrPDB Length = 242 Score = 224 bits (572), Expect = 2e-59, Method: Composition-based stats. Identities = 70/253 (27%), Positives = 110/253 (43%), Gaps = 34/253 (13%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I GG + + PWQVL+ G G L++ WVLTAAH + + +H + Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQ------KHDASALD 52 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDD----SSHDLMLLRLSEPAELTDAVKVMD 140 + + P Y + + F+ G +D+ L++L+ + + + Sbjct: 53 ----IRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPIC 108 Query: 141 LPTQEPA----LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH------PQ 190 LP +E ASGWG + + L VD+ ++ + C + Sbjct: 109 LPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRG 166 Query: 191 KVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCALPERPSLYT 244 VT MLCAG +GGK +C GD+GG LV + GI SWGS C + +YT Sbjct: 167 SVTANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYT 226 Query: 245 KVVHYRKWIKDTI 257 KV++Y WI++ I Sbjct: 227 KVINYIPWIENII 239 >4DJZ-B nrPDB Length = 251 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 73/260 (28%), Positives = 116/260 (44%), Gaps = 42/260 (16%) Query: 25 IVGGWECEKHSQPWQVLVAS-RGRAVCGGVLVHPQWVLTAAHCIR--------------- 68 I G +K + PW +++ G+ CGG L+ W++TAAHC+ Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 69 ---NKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125 + I+LG+H ++ Q V H+ HP YD + +D+ L+ Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNT-----------FENDVALVE 109 Query: 126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185 L E L V + LP G SGWG + F P+ L +++ ++ + C Sbjct: 110 LLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDHSTCQ 167 Query: 186 QVH---PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCAL 236 + + +KVT+ M+CAG GGK C+GDSGGP+V L G SWG + C Sbjct: 168 KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD-CGK 226 Query: 237 PERPSLYTKVVHYRKWIKDT 256 +R +Y+ + H + WI+ Sbjct: 227 KDRYGVYSYIHHNKDWIQRV 246 >4IW4-E nrPDB Length = 279 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 75/278 (26%), Positives = 112/278 (40%), Gaps = 57/278 (20%) Query: 25 IVGGWECEKHSQPWQVLVASRGRA-------VCGGVLVHPQWVLTAAHCIRNKS------ 71 I+GG E PWQ L+ + G L+ W+LTAAH +R++ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 72 -------VILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124 + LG H + + + HP +++ + +HD+ L+ Sbjct: 61 PVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNI-----------QNYNHDIALV 108 Query: 125 RLSEPAELTDAVKVMDLPT---QEPALGTTCYASGWGSIEPE----------EFLTPKKL 171 +L EP L V + LP + PA +GWG P L Sbjct: 109 QLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVL 168 Query: 172 QCVDLHVISNDVCAQVHPQK-----VTKFMLCAGRWTGGKSTCSGDSGGPLV------CN 220 Q V L V+ + C + + VT+ M CAG + GGK TC GDSGG V Sbjct: 169 QYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQR 228 Query: 221 GVLQGITSW-GSEPCALPERPSLYTKVVHYRKWIKDTI 257 V+QG+ SW G E C + +YTKV +Y W+ + + Sbjct: 229 WVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQM 266 >1GPZ-A nrPDB Length = 399 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 71/251 (28%), Positives = 104/251 (41%), Gaps = 21/251 (8%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 +I+GG + + + PWQV GR GG L+ +W+LTAAH + K SL Sbjct: 155 RQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLD 212 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 V ++ HP+ +S+ + + D+ LL L L + + L Sbjct: 213 VFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 272 Query: 142 PTQE--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-----VTK 194 P + LG Y SG+G +E + L+ V L V + C K ++ Sbjct: 273 PDNDTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 329 Query: 195 FMLCAGRWTGGKSTCSGDSGG------PLVCNGVLQGITSWGSEPCALPERPSLYTKVVH 248 M CAG + + C GDSGG P V GI SWG C+ YTKV++ Sbjct: 330 NMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI-GCSRG--YGFYTKVLN 386 Query: 249 YRKWIKDTIVA 259 Y WIK + Sbjct: 387 YVDWIKKEMEE 397 >2QY0-B nrPDB Length = 242 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 71/248 (28%), Positives = 103/248 (41%), Gaps = 21/248 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+GG + + + PWQV GR GG L+ +W+LTAAH + K SL Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 V ++ HP+ +S+ + + D+ LL L L + + LP Sbjct: 59 GHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDN 118 Query: 145 E--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-----VTKFML 197 + LG Y SG+G +E + L+ V L V + C K ++ M Sbjct: 119 DTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 198 CAGRWTGGKSTCSGDSGG------PLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRK 251 CAG + + C GDSGG P V GI SWG C+ YTKV++Y Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI-GCSRG--YGFYTKVLNYVD 232 Query: 252 WIKDTIVA 259 WIK + Sbjct: 233 WIKKEMEE 240 >1ZJK-A nrPDB Length = 403 Score = 223 bits (570), Expect = 5e-59, Method: Composition-based stats. Identities = 71/255 (27%), Positives = 111/255 (43%), Gaps = 34/255 (13%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +I GG + + PWQVL+ G G L++ WVLTAAH + + +H Sbjct: 160 GQIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQ------KHDASA 211 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDD----SSHDLMLLRLSEPAELTDAVKV 138 + + + P Y + + F+ G +D+ L++L+ + + Sbjct: 212 LD----IRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP 267 Query: 139 MDLPTQEPA----LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH------ 188 + LP +E ASGWG + + L VD+ ++ + C + Sbjct: 268 ICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTAAYEKPPYP 325 Query: 189 PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVC------NGVLQGITSWGSEPCALPERPSL 242 VT MLCAG +GGK +C GDSGG LV + GI SWGS C + + Sbjct: 326 RGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGV 385 Query: 243 YTKVVHYRKWIKDTI 257 YTKV++Y WI++ I Sbjct: 386 YTKVINYIPWIENII 400 >1MD7-A nrPDB Length = 328 Score = 223 bits (569), Expect = 6e-59, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 104/249 (41%), Gaps = 21/249 (8%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 RI+GG + + + PWQV GR GG L+ +W+LTAAH + K SL Sbjct: 87 RQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLD 144 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141 V ++ HP+ +S+ + + D+ LL L L + + L Sbjct: 145 VFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 204 Query: 142 PTQE--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-----VTK 194 P + LG Y SG+G +E + L+ V L V + C K ++ Sbjct: 205 PDNDTFYDLGLMGYVSGFGVMEEK---IAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 261 Query: 195 FMLCAGRWTGGKSTCSGDSGG------PLVCNGVLQGITSWGSEPCALPERPSLYTKVVH 248 M CAG + + C GD+GG P V GI SWG C+ YTKV++ Sbjct: 262 NMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGI-GCSRG--YGFYTKVLN 318 Query: 249 YRKWIKDTI 257 Y WIK + Sbjct: 319 YVDWIKKEM 327 >5UBM-A nrPDB Length = 252 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 69/260 (26%), Positives = 103/260 (39%), Gaps = 37/260 (14%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 RI+GG + + + PWQV + GG L++ WVLTAAH + + S Sbjct: 1 RIIGGSDADIKNFPWQVFFDN---PWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 84 ED---TGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 ++ H F HP + + + + +D+ L+RL +P ++ V + Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRT----NFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 141 LPTQEPAL----GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK----- 191 LP G SGWG E + +L+ L V C +V +K Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRTEKRDR--AVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 192 ----VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPERP 240 T M+CAG G +C GDSGG G+ SWG + C Sbjct: 172 EAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---Y 226 Query: 241 SLYTKVVHYRKWIKDTIVAN 260 LYT+V +Y WI T+ N Sbjct: 227 GLYTRVKNYVDWIMKTMQEN 246 >1ELV-A nrPDB Length = 333 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 69/262 (26%), Positives = 103/262 (39%), Gaps = 37/262 (14%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 RI+GG + + + PWQV + GG L++ WVLTAAH + + S Sbjct: 80 KQRIIGGSDADIKNFPWQVFFDN---PWAGGALINEYWVLTAAHVVEGNREPTMYVGSTS 136 Query: 82 HPED---TGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 ++ H F HP + + + + +D+ L+RL +P ++ V Sbjct: 137 VQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRT----NFDNDIALVRLKDPVKMGPTVSP 192 Query: 139 MDLPTQEPAL----GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK--- 191 + LP G SGWG E + +L+ L V C +V +K Sbjct: 193 ICLPGTSSDYNLMDGDLGLISGWGRTEKRDR--AVRLKAARLPVAPLRKCKEVKVEKPTA 250 Query: 192 ------VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPE 238 T M+CAG G +C GDSGG G+ SWG + C Sbjct: 251 DAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT-- 306 Query: 239 RPSLYTKVVHYRKWIKDTIVAN 260 LYT+V +Y WI T+ N Sbjct: 307 -YGLYTRVKNYVDWIMKTMQEN 327 >1YM0-A nrPDB Length = 238 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 73/251 (29%), Positives = 110/251 (43%), Gaps = 28/251 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGR--AVCGGVLVHPQWVLTAAHCIRNK----SVILLGRH 78 IVGG E + PWQV V + CGG +++ +WV+ AAHC++ + +++G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 79 SLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 Q V F + YD + L+N D+ +++ + V Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLEN-----------DVSVIKTAVAITFDINVGP 109 Query: 139 MDLPT-QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-PQKVTKFM 196 + P + SGWG+I P L+ V L++ +N C V+ + M Sbjct: 110 ICAPDPANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDM 169 Query: 197 LCAGRWTG--GKSTCSGDSGGPLVCNG-----VLQGITSWGSEPCALPERPSLYTKVVHY 249 +CA TG + +C GDSGGPL L GI SWG CA P +Y++V + Sbjct: 170 ICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGI-GCA-SGYPGVYSRVGFH 227 Query: 250 RKWIKDTIVAN 260 WI DTI N Sbjct: 228 AGWITDTITNN 238 >4J1Y-A nrPDB Length = 397 Score = 213 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 37/262 (14%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81 +R +GG + + + PWQV + GG L++ WVLTAAH + + S Sbjct: 144 KARAIGGSDADIKNFPWQVFFDN---PWAGGALINEYWVLTAAHVVEGNREPTMYVGSTS 200 Query: 82 HPED---TGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 ++ H F HP + + + + +D+ L+RL +P ++ V Sbjct: 201 VQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRT----NFDNDIALVRLKDPVKMGPTVSP 256 Query: 139 MDLPTQEPAL----GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK--- 191 + LP G SGWG E + +L+ L V C +V +K Sbjct: 257 ICLPGTSSDYNLMDGDLGLISGWGRTEKRDR--AVRLKAARLPVAPLRKCKEVKVEKPTA 314 Query: 192 ------VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-------VLQGITSWGSEPCALPE 238 T M+CAG G +C GDSGG G+ SWG + C Sbjct: 315 DAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT-- 370 Query: 239 RPSLYTKVVHYRKWIKDTIVAN 260 LYT+V +Y WI T+ N Sbjct: 371 -YGLYTRVKNYVDWIMKTMQEN 391 >5KWM-A nrPDB Length = 230 Score = 213 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 77/243 (31%), Positives = 110/243 (45%), Gaps = 27/243 (11%) Query: 25 IVGGWECEKHSQPWQVLVAS-RGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRHS 79 IVGG + P+ V + + G+ CGG L P V+TAAHC ++ GR Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 + E T V +V++ + HP Y + D+ +L L P + + Sbjct: 61 MSSNEGT--VSKVTNVWVHPEYQDAAK-----------GFDVSVLTLEAPVKE----API 103 Query: 140 DLPTQE---PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM 196 +L + A T GWG+ E LQ + V S+D C Q + + M Sbjct: 104 ELAKADDAGYAPDTAATILGWGNTS-EGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAM 162 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 +CAG GG TC GDSGGP+V N L G+TSWG E CA P +P +Y +V Y + + Sbjct: 163 VCAGVPEGGVDTCQGDSGGPMVVNNKLIGVTSWG-EGCARPGKPGVYARVGAYYDVLMEQ 221 Query: 257 IVA 259 I A Sbjct: 222 INA 224 >2PKA-B nrPDB Length = 152 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 94/150 (62%), Positives = 112/150 (74%), Gaps = 2/150 (1%) Query: 114 GDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEP--EEFLTPKKL 171 G D SHDLMLLRL PA++TDAVKV++LPTQEP LG+TC ASGWGSIEP ++F P ++ Sbjct: 3 GKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDEI 62 Query: 172 QCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS 231 QCV L ++ N CA HP KVT+ MLCAG GGK TC GDSGGPL+CNG+ QGITSWG Sbjct: 63 QCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGH 122 Query: 232 EPCALPERPSLYTKVVHYRKWIKDTIVANP 261 PC +PS+YTK++ Y WI DTI NP Sbjct: 123 TPCGSANKPSIYTKLIFYLDWIDDTITENP 152 >1EQ9-A nrPDB Length = 222 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 78/241 (32%), Positives = 114/241 (47%), Gaps = 25/241 (10%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR-----NKSVILLGRHS 79 IVGG + P+QV + G CG ++ VLTAAHC+ N+ + +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 80 LFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 L ++G V+ V + + YD LL+N D+ L+ L+ P + D V+ + Sbjct: 61 LS---ESGDVYDVEDAVVNKNYDDFLLRN-----------DVALVHLTNPIKFNDLVQPI 106 Query: 140 DLPTQEPALGT-TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 198 L T + L + C +GWGS TP LQ ++L V C + +V +C Sbjct: 107 KLSTNDEDLESNPCTLTGWGSTRL-GGNTPNALQEIELIVHPQKQCER-DQWRVIDSHIC 164 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 G+ C GDSGGPLV NG GI S+GS PCAL P +YT+V + WI + Sbjct: 165 T-LTKRGEGACHGDSGGPLVANGAQIGIVSFGS-PCAL-GEPDVYTRVSSFVSWINANLK 221 Query: 259 A 259 Sbjct: 222 K 222 >2XRC-A nrPDB Length = 565 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 77/247 (31%), Positives = 109/247 (44%), Gaps = 33/247 (13%) Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSVILLGRHS 79 RIVGG + PWQV + CGG+ + W+LTAAHC+R ++ I Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 380 Query: 80 LFHPEDTGQVFQ-VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKV 138 HP+ V + V H Y+ +N D+ L+ + + D Sbjct: 381 WIHPDLKRIVIEYVDRIIFHENYNAGTYQN-----------DIALIEMKKDGNKKDCELP 429 Query: 139 MDLPTQEP------ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKV 192 +P P TC SGWG + E + LQ ++ +ISN C++ + + Sbjct: 430 RSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRF 485 Query: 193 TK-FMLCAGRWTGGKSTCSGDSGGPLVCNG-----VLQGITSWGSEPCALPERPSLYTKV 246 + M CAG + G C GDSGGPLVC + G+ SWG E C PE P +YTKV Sbjct: 486 YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKV 544 Query: 247 VHYRKWI 253 +Y WI Sbjct: 545 ANYFDWI 551 >1AE5-A nrPDB Length = 225 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 76/244 (31%), Positives = 115/244 (47%), Gaps = 31/244 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRHSL 80 IVGG + P+ + ++GR CGG L+H ++V+TAA C +++ S ++LG + L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 81 FHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 E + Q F +S + YD + +DLMLL+L A LT +V ++ Sbjct: 61 RRRERQSRQTFSISSMSEN-GYDP-----------QQNLNDLMLLQLDREANLTSSVTIL 108 Query: 140 DLPTQEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 197 LP Q + GT C +GWGS L + + V++ V D C + Sbjct: 109 PLPLQNATVEAGTRCQVAGWGSQRSGGRL-SRFPRFVNVTVTPEDQC--------RPNNV 159 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 C G T C+GD G PLVC G+ G+ S+ PC P +T+V +R WI + Sbjct: 160 CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 217 Query: 258 VANP 261 NP Sbjct: 218 -NNP 220 >2OLG-A nrPDB Length = 278 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 72/270 (26%), Positives = 119/270 (44%), Gaps = 47/270 (17%) Query: 23 SRIVGGWECEKHSQPWQVLVASRG-----RAVCGGVLVHPQWVLTAAHCIRNK------- 70 +I+ G + PW ++ + + CGG L++ ++++TAAHC+ + Sbjct: 21 DKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGA 80 Query: 71 -SVILLGRHSL-FHPEDTGQV----------FQVSHSFPHPLYDMSLLKNRFLRPGDDSS 118 + + LG + P+ G V + + HP Y + D Sbjct: 81 LNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDY---------VDGSKDRY 131 Query: 119 HDLMLLRLSEPAELTDAVKVMDL--PTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDL 176 HD+ L+RL+ E T+ ++ + L P +E +G GWG E ++ T K Q + + Sbjct: 132 HDIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIK--QKLAV 189 Query: 177 HVISNDVCAQVH---PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG-----VLQGITS 228 V+ + CA+ +V LCAG K +C GDSGGPL+ L+G+ S Sbjct: 190 PVVHAEQCAKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGLVS 248 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 +G+ C P +YTKV YR WI+ I Sbjct: 249 FGAT-CGTEGWPGIYTKVGKYRDWIEGNIR 277 >5O32-I nrPDB Length = 244 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 76/246 (30%), Positives = 108/246 (43%), Gaps = 33/246 (13%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSVILLGRHSL 80 IVGG + PWQV + CGG+ + W+LTAAHC+R ++ I Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 81 FHPEDTGQVFQ-VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 139 HP+ V + V H Y+ +N D+ L+ + + D Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQN-----------DIALIEMKKDGNKKDCELPR 109 Query: 140 DLPTQEP------ALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVT 193 +P P TC SGWG + E + LQ ++ +ISN C++ + + Sbjct: 110 SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFY 165 Query: 194 K-FMLCAGRWTGGKSTCSGDSGGPLVCNG-----VLQGITSWGSEPCALPERPSLYTKVV 247 + M CAG + G C GDSGGPLVC + G+ SWG E C PE P +YTKV Sbjct: 166 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVA 224 Query: 248 HYRKWI 253 +Y WI Sbjct: 225 NYFDWI 230 >1PQ7-A nrPDB Length = 224 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 70/236 (29%), Positives = 101/236 (42%), Gaps = 21/236 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSV--ILLGRHSLFH 82 IVGG P+ V ++ G CGG L++ VLTAAHC+ + + SL Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 G +S HP Y +++DL +L+LS + L Sbjct: 61 TSG-GITSSLSSVRVHPSYS-------------GNNNDLAILKLSTSIPSGGNIGYARLA 106 Query: 143 T--QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP-QKVTKFMLCA 199 +P G++ +GWG+ TP L V + ++S C + +T M CA Sbjct: 107 ASGSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCA 166 Query: 200 GRWTGGKSTCSGDSGGPLV-CNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIK 254 G +GGK +C GDSGGP+V + L G SWG CA P +Y V R +I Sbjct: 167 GVSSGGKDSCQGDSGGPIVDSSNTLIGAVSWG-NGCARPNYSGVYASVGALRSFID 221 >1PPF-E nrPDB Length = 218 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 77/240 (32%), Positives = 110/240 (45%), Gaps = 28/240 (11%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVIL----LGRHSL 80 IVGG H+ P+ V + RG CG L+ P +V++AAHC+ N +V LG H+L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E T QVF V F + YD L N D+++L+L+ A + V+V Sbjct: 61 SRREPTRQVFAVQRIFEN-GYDPVNLLN-----------DIVILQLNGSATINANVQVAQ 108 Query: 141 LPTQEPALGT--TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 198 LP Q LG C A GWG + + LQ +++ V++ +C + +C Sbjct: 109 LPAQGRRLGNGVQCLAMGWGLLGRNRGIAS-VLQELNVTVVT-SLCRRS--------NVC 158 Query: 199 AGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 C GDSG PLVCNG++ GI S+ CA P + V + WI I Sbjct: 159 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >4X0L-C nrPDB Length = 259 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 66/269 (24%), Positives = 104/269 (38%), Gaps = 47/269 (17%) Query: 20 LILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI----RNKSVILL 75 + RI+GG K S PWQ + S G L++ QW+LT A + + Sbjct: 10 NPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKD 69 Query: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 +L Q+ ++ HP Y D+ L++L + + + Sbjct: 70 IAPTLTLYVGKKQLVEIEKVVLHPNYSQV---------------DIGLIKLKQKVSVNER 114 Query: 136 VKVMDLPTQEPA-LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-----P 189 V + LP+++ A +G Y SGWG F L+ V L V D C + + P Sbjct: 115 VMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVP 172 Query: 190 QKVT------------KFMLCAGRWTGGKSTCSGDSGGPLVCN------GVLQGITSWGS 231 +K T + CAG + TC GD+G + GI S+ Sbjct: 173 EKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF-D 231 Query: 232 EPCALPERPSLYTKVVHYRKWIKDTIVAN 260 + CA+ E +Y KV + W++ TI N Sbjct: 232 KSCAVAE-YGVYVKVTSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 203 bits (517), Expect = 7e-53, Method: Composition-based stats. Identities = 66/269 (24%), Positives = 104/269 (38%), Gaps = 47/269 (17%) Query: 20 LILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI----RNKSVILL 75 + RI+GG K S PWQ + S G L++ QW+LT A + + Sbjct: 66 NPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKD 125 Query: 76 GRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDA 135 +L Q+ ++ HP Y D+ L++L + + + Sbjct: 126 IAPTLTLYVGKKQLVEIEKVVLHPNYSQV---------------DIGLIKLKQKVSVNER 170 Query: 136 VKVMDLPTQEPA-LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-----P 189 V + LP+++ A +G Y SGWG F L+ V L V D C + + P Sbjct: 171 VMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVP 228 Query: 190 QKVT------------KFMLCAGRWTGGKSTCSGDSGGPLVCN------GVLQGITSWGS 231 +K T + CAG + TC GD+G + GI S+ Sbjct: 229 EKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF-D 287 Query: 232 EPCALPERPSLYTKVVHYRKWIKDTIVAN 260 + CA+ E +Y KV + W++ TI N Sbjct: 288 KSCAVAE-YGVYVKVTSIQDWVQKTIAEN 315 >2B9L-A nrPDB Length = 394 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 70/264 (26%), Positives = 99/264 (37%), Gaps = 45/264 (17%) Query: 29 WECEKHSQPWQVLV--------ASRGRAVCGGVLVHPQWVLTAAHCIR------NKSVIL 74 E E PW V V + + VCGG L+ P VLT AHC+ + I Sbjct: 135 NEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIR 194 Query: 75 LGRHSLFHPED--TGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL 132 G ++ Q ++ H ++ + N D+ LL L P Sbjct: 195 AGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVN-----------DVALLLLDRPLVQ 243 Query: 133 TDAVKVMDLPTQEPALGTT-CYASGWGSIEPEEF-LTPKKLQCVDLHVISNDVCAQVHPQ 190 D + + LP Q +T C+ASGWG E L+ + L + D C Sbjct: 244 ADNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRN 303 Query: 191 K-------VTKFMLCAGRWTGGKSTCSGDSGGPLVC-------NGVLQGITSWGSEPCAL 236 + + +CAG GK TC+GD G PL C + GI +WG C Sbjct: 304 TRLGLKFVLDQTFVCAGG-EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGI-GCGD 361 Query: 237 PERPSLYTKVVHYRKWIKDTIVAN 260 P +Y V H+R WI + A Sbjct: 362 ENVPGVYANVAHFRNWIDQEMQAK 385 >2HLC-A nrPDB Length = 230 Score = 198 bits (503), Expect = 3e-51, Method: Composition-based stats. Identities = 66/243 (27%), Positives = 106/243 (43%), Gaps = 29/243 (11%) Query: 25 IVGGWECEKHSQPWQV----LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL 80 I+ G+E P+Q + + R CGG L+ +W+LTAAHC+ + +++ S Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 81 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140 E V H +++ D +D+ L+++ E TD ++ + Sbjct: 61 VQYEG-EAVVNSERIISHSMFNP-----------DTYLNDVALIKIPH-VEYTDNIQPIR 107 Query: 141 LPTQEPALGTT----CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-PQKVTKF 195 LP+ E SGWG + + LQ VI ND CAQ + P + + Sbjct: 108 LPSGEELNNKFENIWATVSGWGQSNTDTVI----LQYTYNLVIDNDRCAQEYPPGIIVES 163 Query: 196 MLCAGRWTGGKSTCSGDSGGPLVC--NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 +C G + GKS C GDSGGP V +L G+ S+ S +P +++V Y WI Sbjct: 164 TIC-GDTSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWI 222 Query: 254 KDT 256 + Sbjct: 223 QQN 225 >4F4O-C nrPDB Length = 347 Score = 196 bits (499), Expect = 7e-51, Method: Composition-based stats. Identities = 66/267 (24%), Positives = 104/267 (38%), Gaps = 47/267 (17%) Query: 22 LSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSVILLGR 77 + RI+GG K S PWQ + S G L++ QW+LT A +R N + Sbjct: 100 VQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDIA 159 Query: 78 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 +L Q ++ HP D+S+ D+ L++L + + + V Sbjct: 160 PTLRLYVGKKQEVEIEKVIFHP---------------DNSTVDIGLIKLKQKVPVNERVM 204 Query: 138 VMDLPTQEPA-LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVH-----PQK 191 + LP+++ +G Y SGWG + L+ V L V + C Q + P+K Sbjct: 205 PICLPSKDYVNVGLVGYVSGWGR--NANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEK 262 Query: 192 VT------------KFMLCAGRWTGGKSTCSGDSGGPLVCN------GVLQGITSWGSEP 233 T + CAG + TC GD+G + GI S+ + Sbjct: 263 KTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSF-DKS 321 Query: 234 CALPERPSLYTKVVHYRKWIKDTIVAN 260 C E +Y +V WI+ TI N Sbjct: 322 CRTAE-YGVYVRVTSILDWIQTTIADN 347 >6BQM-A nrPDB Length = 506 Score = 195 bits (496), Expect = 1e-50, Method: Composition-based stats. Identities = 63/267 (23%), Positives = 108/267 (40%), Gaps = 47/267 (17%) Query: 16 GAAPLILSRIVGGWECEKHSQPWQVLVASRGRA--VCGGVLVHPQWVLTAAHCIRNKS-- 71 G + SRI+GG + P+ V + +R + CGG + ++VLTAAHC+ + Sbjct: 2 GTESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPA 61 Query: 72 --VILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS-- 127 +LLG + + V + H Y + + +D+ +L L Sbjct: 62 KGDVLLGAFDMNDVNTAER-IHVRQIYVHNSYITASM-----------GNDIAVLELERD 109 Query: 128 ----EPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPK---KLQCVDLHVIS 180 +++D+ +L P G+G+ + + L V + + Sbjct: 110 PLPRRSVQISDSSDFNELTKDSP-----MTVIGFGNRKEVDGEKSDPATILHQVQVPFVP 164 Query: 181 NDVC--------AQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLV---CNGVLQ-GITS 228 C A+ + ++T CAG + GK CSGD+GGP+ NG Q G+ S Sbjct: 165 LPECKTKGSDQDAKNNYSQLTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVS 222 Query: 229 WGSEPCALPERPSLYTKVVHYRKWIKD 255 WG + C P +YT + + W+ D Sbjct: 223 WG-DGCGRANSPGVYTNLSVFNDWLDD 248 >1SI5-H nrPDB Length = 240 Score = 193 bits (491), Expect = 6e-50, Method: Composition-based stats. Identities = 76/249 (30%), Positives = 107/249 (42%), Gaps = 39/249 (15%) Query: 25 IVGG--WECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRH 78 +V G W V + R + +CGG L+ WVLTA C ++ LG H Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 79 SL--FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAV 136 + E QV VS P DL+L++L+ PA L D V Sbjct: 58 DVHGRGDEKCKQVLNVSQLVYGP-----------------EGSDLVLMKLARPAVLDDFV 100 Query: 137 KVMDLPTQEPALG--TTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVT- 193 +DLP + T+C GWG L+ L+++ N+ C+Q H KVT Sbjct: 101 STIDLPNYGSTIPEKTSCSVYGWGYTGLIN--YDGLLRVAHLYIMGNEKCSQHHRGKVTL 158 Query: 194 -KFMLCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGSEPCALPERPSLYTKVVH 248 + +CAG G C GD GGPLVC ++ G+ G CA+P RP ++ +V + Sbjct: 159 NESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPG-RGCAIPNRPGIFVRVAY 217 Query: 249 YRKWIKDTI 257 Y KWI I Sbjct: 218 YAKWIHKII 226 >3I77-A nrPDB Length = 230 Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats. Identities = 66/242 (27%), Positives = 97/242 (40%), Gaps = 32/242 (13%) Query: 25 IVGGWECEKHSQPWQV-LVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +VGG + P+ V L+ CGG L VLTAAHC+ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVS-------GSGNNTSI 53 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 TG V + S + +L+ + D L++L++ ++ PT Sbjct: 54 TATGGVVDLQSSSAVKVRSTKVLQAPGFTK-ETYGKDWALIKLAQ---------PINQPT 103 Query: 144 QEPALGT-----TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VTKFML 197 + A T T +GWG+ E + L ++ +S+ C V M+ Sbjct: 104 LKIATTTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMI 162 Query: 198 CAGRWT-GGKSTCSGDSGGPLVC-----NGVLQGITSWGSEPCALPERPSLYTKVVHYRK 251 CAG GG TC GDSGGP+ + GI SWG CA P P +YT+V + Sbjct: 163 CAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFAS 221 Query: 252 WI 253 I Sbjct: 222 AI 223 >2ASU-B nrPDB Length = 234 Score = 190 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 70/241 (29%), Positives = 102/241 (42%), Gaps = 22/241 (9%) Query: 25 IVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83 +VGG + PW V + +R G+ CGG LV QW+LTA C + + L G Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWL-- 55 Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143 G +FQ L + + K G L+LL+L L V ++ LP Sbjct: 56 ---GTLFQNPQHGEPSLQRVPVAKMVCGPSGSQ----LVLLKLERSVTLNQRVALICLPP 108 Query: 144 QEPAL--GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGR 201 + + GT C +GWG + L L+VISN C H +V + +C Sbjct: 109 EWYVVPPGTKCEIAGWGETK--GTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEG 166 Query: 202 WTGGKSTCSGDSGGPLVC----NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 C GD GGPL C + VL+GI + CA P+++T+V + WI + Sbjct: 167 LLAPVGACEGDYGGPLACFTHNSWVLEGIII-PNRVCARSRWPAVFTRVSVFVDWIHKVM 225 Query: 258 V 258 Sbjct: 226 R 226 >4LK4-A nrPDB Length = 357 Score = 189 bits (481), Expect = 9e-49, Method: Composition-based stats. Identities = 69/254 (27%), Positives = 104/254 (40%), Gaps = 30/254 (11%) Query: 21 ILSRIVGGWECEKHSQPWQVLVASRG-----RAVCGGVLVHPQWVLTAAHCIRNKS---- 71 I SRI+ G P V + RG CGG + ++VLTAAHC ++S Sbjct: 7 ISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASV 66 Query: 72 VILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 +++G + L + + + H Y S L N D+ ++ L++ + Sbjct: 67 DVIIGAYDLNNSSQGER-IAAQKIYRHLSYSPSNLLN-----------DIAIVELAQTSS 114 Query: 132 LTDAVKVMDLPTQEPALGTTCYASGWGSI-EPEEFLTPKKLQCVDLHVISNDVCAQVHPQ 190 L T +GWG + + LQ VD+ ++S +C V Sbjct: 115 LPAITLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQH 174 Query: 191 KVTK----FMLCAGRWTGGKSTCSGDSGGPLVCN-GVLQ-GITSWGSEPCALPERPSLYT 244 ++ CA R T K +C GD+GGP+V G Q GI SWG E CA +YT Sbjct: 175 GISSDPNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYT 232 Query: 245 KVVHYRKWIKDTIV 258 V ++R WI Sbjct: 233 NVSYFRDWITKHTN 246 >3BEU-A nrPDB Length = 224 Score = 187 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 64/240 (26%), Positives = 97/240 (40%), Gaps = 34/240 (14%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 +VGG + P+ V ++ CGG L VLTAAHC+ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 TG V + S + +L+ + D L++L++ ++ PT Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQAPGFTK-ETYGKDWALIKLAQ---------PINQPTL 99 Query: 145 EPALGT-----TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VTKFMLC 198 + A T T +GWG+ E + L ++ +S+ C V M+C Sbjct: 100 KIATTTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMIC 158 Query: 199 AGRWTGGKSTCSGDSGGPLVC-----NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 AG T + TC GDSGGP+ V GI SWG E CA + +YT+V + I Sbjct: 159 AGYDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWG-EGCARKGKYGVYTEVSTFASAI 217 >2FMJ-A nrPDB Length = 222 Score = 185 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 64/240 (26%), Positives = 100/240 (41%), Gaps = 36/240 (15%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 +VGG + P+ V ++ CGG L VLTAAHC+ G + Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVS-------GSGNNTSIT 49 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144 TG V + S + +L+ + + D L++L++ ++ PT Sbjct: 50 ATGGVVDLQSSSAVKVRSTKVLQ---APGYNGTGKDWALIKLAQ---------PINQPTL 97 Query: 145 EPALGT-----TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQK-VTKFMLC 198 + A T T +GWG+ E + L ++ +S+ C + + V +C Sbjct: 98 KIATTTAYNQGTFTVAGWGA-NREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEIC 156 Query: 199 AGRWTGGKSTCSGDSGGPLVC-----NGVLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253 AG TGG TC GDSGGP+ + GI SWG E CA + +YT+V + I Sbjct: 157 AGYDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-EGCARKGKYGVYTEVSTFASAI 215 >3H7T-A nrPDB Length = 235 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 59/244 (24%), Positives = 97/244 (39%), Gaps = 21/244 (8%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+GG + + +PW V V + CGG ++ +V+TAA C+ + H Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGSSYR 60 Query: 85 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTD-AVKVMDLPT 143 T ++ Y ++N + ++ P +L D K ++LP+ Sbjct: 61 TTKGTSVMAKKIYIVRYHPLTMQNNY-----------AVIETEMPIKLDDKTTKKIELPS 109 Query: 144 --QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQ-----KVTKFM 196 +P T+ SGWGS + L + V+ C + + Q + + Sbjct: 110 LLYDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGV 169 Query: 197 LCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 256 CAG GD+G P V NG L G+ S+ S E PS++ +V +Y IKD Sbjct: 170 FCAGGEYDETYIGYGDAGDPAVQNGTLVGVASYISSM--PSEFPSVFLRVGYYVLDIKDI 227 Query: 257 IVAN 260 I Sbjct: 228 ISGK 231 >5XW8-A nrPDB Length = 133 Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats. Identities = 49/139 (35%), Positives = 75/139 (53%), Gaps = 12/139 (8%) Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82 +IVGG+ C +S P+QV + S G CGG L++ QWV++AAHC +++ + LG H++ Sbjct: 7 DKIVGGYTCAANSIPYQVSLNS-GSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV 65 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 E Q + HP ++ + L +D+ML++LS PA L V + LP Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTL-----------DNDIMLIKLSSPATLNSRVATVSLP 114 Query: 143 TQEPALGTTCYASGWGSIE 161 A GT C SGWG+ + Sbjct: 115 RSCAAAGTECLISGWGNTK 133 >1M9U-A nrPDB Length = 241 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 70/252 (27%), Positives = 97/252 (38%), Gaps = 32/252 (12%) Query: 25 IVGGWECEKHSQPWQVLVASRG---RAVCGGVLVHPQWVLTAAHCIR----NKSVILLGR 77 ++GG PWQ+ + CG L+ L+A+HC+ N ++ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 78 HSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK 137 T Q V H Y S+D+ +L L+ L ++ Sbjct: 61 WQQSDTSGT-QTANVDSYTMHENYGAGTA---------SYSNDIAILHLATSISLGGNIQ 110 Query: 138 VMDLPTQEPA--LGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQ----VHPQK 191 LP GTTC SGWG + L P LQ + VI+ C V Sbjct: 111 AAVLPANNNNDYAGTTCVISGWGRTDGTNNL-PDILQKSSIPVITTAQCTAAMVGVGGAN 169 Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNG---VLQGITSW----GSEPCALPERPSLYT 244 + +C G C+GDSGGPL C + G+TSW G C LP+ PS+YT Sbjct: 170 IWDNHICVQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSVYT 228 Query: 245 KVVHYRKWIKDT 256 +V Y WI D Sbjct: 229 RVSAYLGWIGDN 240 >3H7O-A nrPDB Length = 228 Score = 158 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 66/243 (27%), Positives = 100/243 (41%), Gaps = 25/243 (10%) Query: 27 GGWECEKHSQPWQVLVAS---RGRAVCGGVLVHPQWVLTAAHCIRNKS--VILLGRHSLF 81 GG + + PW V V + CGG ++ +VLTAAHC+ ++ I++ S Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 82 HPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAEL-TDAVKVMD 140 ED G+ Y ++N D+ +L LS P +L K Sbjct: 62 LWEDPGKSDPYVSHVYLSFYRQETMEN-----------DIAILELSRPLKLDGLKSKPAK 110 Query: 141 LPTQE--PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC-AQVHPQKVTKFML 197 LP E P G+ SG+G + + L+ L V+ D C + P ++ + Sbjct: 111 LPDIEFRPKTGSDVLVSGYGDGQTMDPK-DHDLKSAQLTVVDLDECRTKYGPIFLSLQVF 169 Query: 198 CAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 CA G S SGD+G P V L G+ ++ P P ++TKV Y WI+D I Sbjct: 170 CA--QKVGVSLESGDAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDII 225 Query: 258 VAN 260 Sbjct: 226 KKK 228 >2I6S-A nrPDB Length = 517 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 59/230 (25%), Positives = 94/230 (40%), Gaps = 35/230 (15%) Query: 37 PWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP-EDTGQVFQVSHS 95 PW V + + + C G L+ QWVLTAAHC R+ + L R ++ P G+ F + + Sbjct: 244 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKA 303 Query: 96 FPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPA-------L 148 P +D+ KN+ + D+ LL+L++ +++ + + LP A Sbjct: 304 VISPGFDVFAKKNQGILEFY--GDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQ 361 Query: 149 GTTCYASGWGSIEPEEF------LTPKKLQCVDLHVISNDVCAQVHPQK----------- 191 G+TC + + L KL + CA+V Q+ Sbjct: 362 GSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVR 421 Query: 192 --VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVL----QGITSWG-SEPC 234 VT LC+G +S C G+SGG + G+ SWG PC Sbjct: 422 EVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPC 470 >2WIN-I nrPDB Length = 507 Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 59/248 (23%), Positives = 97/248 (39%), Gaps = 45/248 (18%) Query: 31 CEKHSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT 86 + H QPWQ ++ S+G C G +V +VLTAAHC + HS+ Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGG 284 Query: 87 GQV-FQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQE 145 + ++ HP Y+++ K + D +D+ L++L + ++ + LP E Sbjct: 285 EKRDLEIEVVLFHPNYNINGKKEAGIPEFYD--YDVALIKLKNKLKYGQTIRPICLPCTE 342 Query: 146 PA-------LGTTCYASGWGSIEPEEFLT------PKKLQCVDLHVISNDV---C---AQ 186 TTC + ++ KKL ++++ + D C AQ Sbjct: 343 GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 402 Query: 187 VHPQK---------VTKFMLCAGR--WTGGKSTCSGDSGGPLVCNG----VLQGITSWGS 231 P VT LC G +TC GDSGGPL+ + + G+ SWG Sbjct: 403 YAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGV 462 Query: 232 EPCALPER 239 ++ Sbjct: 463 VDVCKNQK 470 >3F1S-B nrPDB Length = 283 Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 60/235 (25%), Positives = 84/235 (35%), Gaps = 34/235 (14%) Query: 37 PWQVLV-ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHS 95 PWQV + S G+ CGGV++ +VLT A C I + + + +++H Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV-KTYFNRTSQDPLMIKITHV 123 Query: 96 FPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPA-----LGT 150 H YD D +DL LL L P + A + P ++ A T Sbjct: 124 HVHMRYD-----------ADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRT 172 Query: 151 TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC------AGRWTG 204 SGW L + ++ + C QV VT C A W Sbjct: 173 RGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMD 229 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259 G S + + G GVL GS+P L TKV Y W K + A Sbjct: 230 G-SVVTREHRGSWFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIMNA 277 >1DLE-A nrPDB Length = 298 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 59/248 (23%), Positives = 97/248 (39%), Gaps = 45/248 (18%) Query: 31 CEKHSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT 86 + H QPWQ ++ S+G C G +V +VLTAAHC + HS+ Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGG 77 Query: 87 GQV-FQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQE 145 + ++ HP Y+++ K + D +D+ L++L + ++ + LP E Sbjct: 78 EKRDLEIEVVLFHPNYNINGKKEAGIPEFYD--YDVALIKLKNKLKYGQTIRPICLPCTE 135 Query: 146 PA-------LGTTCYASGWGSIEPEEFLT------PKKLQCVDLHVISNDV---C---AQ 186 TTC + ++ KKL ++++ + D C AQ Sbjct: 136 GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 195 Query: 187 VHPQK---------VTKFMLCAGR--WTGGKSTCSGDSGGPLVCNG----VLQGITSWGS 231 P VT LC G +TC GDSGGPL+ + + G+ SWG Sbjct: 196 YAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGV 255 Query: 232 EPCALPER 239 ++ Sbjct: 256 VDVCKNQK 263 >1AKS-B nrPDB Length = 98 Score = 152 bits (384), Expect = 1e-37, Method: Composition-based stats. Identities = 48/99 (48%), Positives = 60/99 (60%), Gaps = 1/99 (1%) Query: 162 PEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNG 221 P LQC+ V+SN C +P ++T M+C G GGK +C GDSGGP+VCNG Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 222 VLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 LQGI SWG CA +P +YTKV +Y WI+ TI AN Sbjct: 61 QLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >2OK5-A nrPDB Length = 752 Score = 151 bits (381), Expect = 4e-37, Method: Composition-based stats. Identities = 59/248 (23%), Positives = 97/248 (39%), Gaps = 45/248 (18%) Query: 31 CEKHSQPWQVLVA----SRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT 86 + H QPWQ ++ S+G C G +V +VLTAAHC + HS+ Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGG 528 Query: 87 GQV-FQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQE 145 + ++ HP Y+++ K + D +D+ L++L + ++ + LP E Sbjct: 529 EKRDLEIEVVLFHPNYNINGKKEAGIPEFYD--YDVALIKLKNKLKYGQTIRPICLPCTE 586 Query: 146 PA-------LGTTCYASGWGSIEPEEFLT------PKKLQCVDLHVISNDV---C---AQ 186 TTC + ++ KKL ++++ + D C AQ Sbjct: 587 GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQ 646 Query: 187 VHPQK---------VTKFMLCAGR--WTGGKSTCSGDSGGPLVCNG----VLQGITSWGS 231 P VT LC G +TC GDSGGPL+ + + G+ SWG Sbjct: 647 YAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGV 706 Query: 232 EPCALPER 239 ++ Sbjct: 707 VDVCKNQK 714 >3H5C-B nrPDB Length = 317 Score = 150 bits (380), Expect = 5e-37, Method: Composition-based stats. Identities = 59/234 (25%), Positives = 83/234 (35%), Gaps = 34/234 (14%) Query: 37 PWQVLV-ASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHS 95 PWQV + S G+ CGGV++ +VLT A C I + + + +++H Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV-KTYFNRTSQDPLMIKITHV 164 Query: 96 FPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPA-----LGT 150 H YD D +DL LL L P + A + P ++ A T Sbjct: 165 HVHMRYD-----------ADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRT 213 Query: 151 TCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC------AGRWTG 204 SGW L + ++ + C QV VT C A W Sbjct: 214 RGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMD 270 Query: 205 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIV 258 G S + + G GVL GS+P L TKV Y W K + Sbjct: 271 G-SVVTREHRGSWFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIMN 317 >2JET-B nrPDB Length = 128 Score = 148 bits (374), Expect = 3e-36, Method: Composition-based stats. Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 15/138 (10%) Query: 28 GWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHC-IRNKSVILLGRHSLFHPED 85 G + S PWQV + + G CGG L+ WV+TAAHC ++ V++ G E+ Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEE 60 Query: 86 TGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP--T 143 QV +++ F +P ++M ++N D+ LL+L+ PA+ ++ V + LP Sbjct: 61 NIQVLKIAQVFKNPKFNMFTVRN-----------DITLLKLATPAQFSETVSAVCLPNVD 109 Query: 144 QEPALGTTCYASGWGSIE 161 + GT C +GWG + Sbjct: 110 DDFPPGTVCATTGWGKTK 127 >1RIW-B nrPDB Length = 147 Score = 148 bits (373), Expect = 3e-36, Method: Composition-based stats. Identities = 40/157 (25%), Positives = 71/157 (45%), Gaps = 28/157 (17%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 ILLGRHSLFHPEDT-GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E ++ + + HP Y+ ++ D+ L++L +P Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 LTDAVKVMDLPTQEPA-----LGTTCYASGWGSIEPE 163 +D + + LP +E A G +GWG+++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET 147 >3VGC-B nrPDB Length = 131 Score = 148 bits (373), Expect = 3e-36, Method: Composition-based stats. Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 15/141 (10%) Query: 25 IVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHC-IRNKSVILLGRHSLFH 82 IV G E S PWQV + + G CGG L++ WV+TAAHC + V++ G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142 + Q +++ F + Y+ + N D+ LL+LS A + V + LP Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTINN-----------DITLLKLSTAASFSQTVSAVCLP 109 Query: 143 TQ--EPALGTTCYASGWGSIE 161 + + A GTTC +GWG Sbjct: 110 SASDDFAAGTTCVTTGWGLTR 130 >1BBR-H nrPDB Length = 150 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 28/153 (18%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ + + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 ILLGRHSLFHPE-DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAE 131 + +G+HS E ++ + + HP Y+ ++ D+ LL+L P E Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 LTDAVKVMDLPTQEPA-----LGTTCYASGWGS 159 L+D + + LP ++ A G +GWG+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGN 143 >2KAI-A nrPDB Length = 80 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 43/80 (53%), Positives = 56/80 (70%) Query: 25 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 84 I+GG ECEK+S PWQV + CGGVLV+P+WVLTAAHC + + LGRH+LF E Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 85 DTGQVFQVSHSFPHPLYDMS 104 +T Q F V+ FPHP +++S Sbjct: 61 NTAQFFGVTADFPHPGFNLS 80 >2HNT-F nrPDB Length = 105 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 36/100 (36%), Positives = 44/100 (44%), Gaps = 10/100 (10%) Query: 167 TPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGR-WTGGK--STCSGDSGGPLVCN--- 220 P LQ V+L ++ VC ++T M CAG GK C GDSGGP V Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 221 ---GVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 GI SWG E C + YT V +KWI+ I Sbjct: 62 NNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 100 >1BBR-E nrPDB Length = 109 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 10/100 (10%) Query: 167 TPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG---GKSTCSGDSGGPLVCN--- 220 P LQ V+L ++ VC ++T M CAG G C GDSGGP V Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 221 ---GVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257 GI SWG E C + YT V +KWI+ I Sbjct: 66 NNRWYQMGIVSWG-EGCDRDGKYGFYTHVFRLKKWIQKVI 104 >3RU4-E nrPDB Length = 96 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 40/98 (40%), Positives = 53/98 (54%), Gaps = 7/98 (7%) Query: 167 TPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN----GV 222 TP +LQ L ++SN C + K+ M+CAG G S+C GDSGGPLVC Sbjct: 2 TPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAG--ASGVSSCMGDSGGPLVCKKNGAWT 59 Query: 223 LQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 L GI SWGS C+ P +Y +V W++ T+ AN Sbjct: 60 LVGIVSWGSSTCSTS-TPGVYARVTALVNWVQQTLAAN 96 >2JET-C nrPDB Length = 99 Score = 114 bits (286), Expect = 4e-26, Method: Composition-based stats. Identities = 39/102 (38%), Positives = 52/102 (50%), Gaps = 7/102 (6%) Query: 163 EEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN-- 220 TP+KLQ L ++S C + K+T M CAG G +C GDSGGPLVC Sbjct: 1 NALKTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAG--ASGVDSCMGDSGGPLVCQKD 58 Query: 221 --GVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260 L GI SWGS C+ P +Y++V W++ + AN Sbjct: 59 GVWTLAGIVSWGSGVCSTS-TPGVYSRVTALMPWVQQILEAN 99 >1EPT-B nrPDB Length = 82 Score = 98.4 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 11/93 (11%) Query: 69 NKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSE 128 ++ + LG H++ E Q + HP ++ + L +D+ML++LS Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTL-----------DNDIMLIKLSS 49 Query: 129 PAELTDAVKVMDLPTQEPALGTTCYASGWGSIE 161 PA L V + LP A GT C SGWG+ + Sbjct: 50 PATLNSRVATVSLPRSCAAAGTECLISGWGNTK 82 >2HNT-C nrPDB Length = 70 Score = 77.6 bits (190), Expect = 4e-15, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 12/70 (17%) Query: 25 IVGGWECEKHSQPWQVLVASRG--RAVCGGVLVHPQWVLTAAHCI----------RNKSV 72 IV G + E PWQV++ + +CG L+ +WVLTAAHC+ N + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 ILLGRHSLFH 82 + +G+HS Sbjct: 61 VRIGKHSRTR 70 >2HNT-E nrPDB Length = 81 Score = 75.3 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 35/82 (42%), Gaps = 15/82 (18%) Query: 87 GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEP 146 ++ + + HP Y+ ++ D+ L++L +P +D + + LP +E Sbjct: 3 EKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVAFSDYIHPVCLPDRET 52 Query: 147 A-----LGTTCYASGWGSIEPE 163 A G +GWG+++ Sbjct: 53 AASLLQAGYKGRVTGWGNLKET 74 >1P3E-A nrPDB Length = 215 Score = 38.7 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 37/112 (33%), Gaps = 7/112 (6%) Query: 46 GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSL 105 G + C G L+ P +LT HC+ N + +P + Y S Sbjct: 28 GGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANMTEFYVPSG 87 Query: 106 LKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGW 157 N S +D +++ T + + T GTT SG+ Sbjct: 88 YINTG-----ASQYDFAVIKTDTNIGNTVGYRSIRQVTN--LTGTTIKISGY 132 >2PFE-A nrPDB Length = 186 Score = 36.8 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 20/43 (46%), Gaps = 9/43 (20%) Query: 192 VTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPC 234 +T+ CA GDSGGP + QG+TS G+ C Sbjct: 128 LTRTTACAEG---------GDSGGPWLTGSQAQGVTSGGTGDC 161 >3LT3-A nrPDB Length = 217 Score = 36.8 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 60/181 (33%), Gaps = 42/181 (23%) Query: 52 GVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFL 111 G ++ P V+T AH + + + + + F+ + P D+++L L Sbjct: 42 GFVISPDRVMTNAHVVAGSNNVTVYAGD--------KPFEATVVSYDPSVDVAILAVPHL 93 Query: 112 RPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKL 171 P +EPA+ V V+ P T E P Sbjct: 94 PPPPLVFA-------AEPAKTGADVVVLGYPGGGNFTATPARI-----REAIRLSGPDI- 140 Query: 172 QCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLV-CNGVLQGITSWG 230 P+ VT+ + T GD+GGPL+ NG + G+ +G Sbjct: 141 --------------YGDPEPVTRDVY-----TIRADVEQGDAGGPLIDLNGQVLGVV-FG 180 Query: 231 S 231 + Sbjct: 181 A 181 >2EA3-A nrPDB Length = 189 Score = 36.0 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 13/28 (46%), Positives = 15/28 (53%) Query: 211 GDSGGPLVCNGVLQGITSWGSEPCALPE 238 GDSGG L+ QG+TS GS C Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >2SFA-A nrPDB Length = 191 Score = 33.7 bits (76), Expect = 0.075, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 13/28 (46%) Query: 211 GDSGGPLVCNGVLQGITSWGSEPCALPE 238 GDSGG L G+TS GS C Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGG 172 >2SGA-A nrPDB Length = 181 Score = 33.7 bits (76), Expect = 0.085, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 16/40 (40%), Gaps = 2/40 (5%) Query: 201 RWTGGKSTCS--GDSGGPLVCNGVLQGITSWGSEPCALPE 238 + C+ GDSGG L G+TS GS C Sbjct: 123 YGMIQTNVCAQPGDSGGSLFAGSTALGLTSGGSGNCRTGG 162 >2OUA-A nrPDB Length = 188 Score = 33.3 bits (75), Expect = 0.098, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 2/36 (5%) Query: 205 GKSTCS--GDSGGPLVCNGVLQGITSWGSEPCALPE 238 S C+ GDSGG + QG+TS GS C Sbjct: 133 RTSVCAEPGDSGGSFISGTQAQGVTSGGSGNCRTGG 168 >1DUE-A nrPDB Length = 242 Score = 32.5 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 41/194 (21%), Positives = 67/194 (34%), Gaps = 38/194 (19%) Query: 42 VASRGRAVCGGVLVHPQWVLTAAHCIR---NKSVILLGRHSLFHPEDTGQVFQVSHSFPH 98 V +G+ GVL+ VLT H + + R S+ ++ P+ Sbjct: 49 VFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTE------TPY 102 Query: 99 PLYDMSLLKNRFLRPGDDSSHDLMLLRLSEP---AELTDAVKVMDLPTQEPALGTTCYAS 155 Y++ + L+ + DL L+RL L D + +GT Sbjct: 103 GEYEVKEI----LQEPFGAGVDLALIRLKPDQNGVSLGDKISP-------AKIGT----- 146 Query: 156 GWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSG- 214 + KL+ + + V Q+H ++ L G G T G++G Sbjct: 147 ------SNDLKDGDKLELIGYPF-DHKV-NQMHRSEIELTTLSRGLRYYGF-TVPGNAGS 197 Query: 215 GPLVCNGVLQGITS 228 G NG L GI S Sbjct: 198 GIFNSNGELVGIHS 211 >5ILB-A nrPDB Length = 474 Score = 31.4 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 21/50 (42%), Gaps = 2/50 (4%) Query: 29 WECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRH 78 +S PWQ + + ++ +LT AHC+ + + + + R Sbjct: 17 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKRR 64 >4FLN-A nrPDB Length = 539 Score = 31.4 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 21/50 (42%), Gaps = 2/50 (4%) Query: 29 WECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRH 78 +S PWQ + + ++ +LT AHC+ + + + + R Sbjct: 57 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKRR 104 >1HPG-A nrPDB Length = 187 Score = 31.0 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 47/181 (25%), Gaps = 43/181 (23%) Query: 56 HPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGD 115 ++ +TA HC + G F + Y + + Sbjct: 24 GARYFVTAGHCTNISANWSASSGGSVVGVREGTSFPTNDYGIV-RYTDGSSPAGTVDLYN 82 Query: 116 DSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVD 175 S+ D+ +G SG +T + V+ Sbjct: 83 GSTQDIS-------------------SAANAVVGQAIKKSG-----STTKVTSGTVTAVN 118 Query: 176 LHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCS--GDSGGPLVCNGVLQGITSWGSEP 233 + V + M+ + CS GDSGG V GI S GS Sbjct: 119 VTV--------NYGDGPVYNMV-------RTTACSAGGDSGGAHFAGSVALGIHS-GSSG 162 Query: 234 C 234 C Sbjct: 163 C 163 >2M5T-A nrPDB Length = 142 Score = 30.6 bits (68), Expect = 0.62, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 24/50 (48%), Gaps = 7/50 (14%) Query: 185 AQVHPQKVTKFMLCAGRWTGGKSTCS-GDSGGPLVCNGVLQGITSWGSEP 233 Q +P+ + +L G+ C GD+GG L+C + GI + G + Sbjct: 82 TQYYPKHIQYNLL------IGEGPCVPGDAGGKLLCRHGVIGIITAGGDG 125 >5JYK-A nrPDB Length = 566 Score = 30.6 bits (68), Expect = 0.63, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Query: 35 SQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILL 75 S PWQ + G ++ + VLT AH + + + + L Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKL 153 >5MRT-A nrPDB Length = 205 Score = 30.2 bits (67), Expect = 0.80, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 15/28 (53%), Gaps = 1/28 (3%) Query: 210 SGDSGGPLV-CNGVLQGITSWGSEPCAL 236 GDSGG + G QG+TS G+ P Sbjct: 146 RGDSGGSWITAAGQAQGLTSGGNLPAGQ 173 >5ILA-A nrPDB Length = 301 Score = 30.2 bits (67), Expect = 0.90, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Query: 35 SQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILL 75 S PWQ + G ++ + VLT AH + + + + L Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKL 153 >3W95-A nrPDB Length = 171 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 12/23 (52%) Query: 211 GDSGGPLVCNGVLQGITSWGSEP 233 GD+GG L C + GI S G Sbjct: 129 GDAGGILRCQHGVVGIVSTGGNG 151 >4FVB-A nrPDB Length = 152 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 12/23 (52%) Query: 211 GDSGGPLVCNGVLQGITSWGSEP 233 GD+GG L C + GI S G Sbjct: 110 GDAGGILRCQHGVVGIVSTGGNG 132 >2HRV-A nrPDB Length = 142 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 24/49 (48%), Gaps = 7/49 (14%) Query: 185 AQVHPQKVTKFMLCAGRWTGGKSTCS-GDSGGPLVCNGVLQGITSWGSE 232 ++ +P+ + +L G+ C GD GG L+C + GI + G + Sbjct: 83 SEYYPKHIQYNLL------IGEGPCEPGDCGGKLLCKHGVIGIVTAGGD 125 >5MRR-A nrPDB Length = 199 Score = 29.5 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 10/55 (18%) Query: 207 STC--SGDSGGPLVCN-GVLQGITSWGS-----EPCALP--ERPSLYTKVVHYRK 251 + C GDSGG + G QG+ S G+ C +P +R SL+ +V Sbjct: 136 NACMGRGDSGGSWFTSAGQAQGVMSGGNVQSNGNNCGIPASQRSSLFERVGPILS 190 >1GBE-A nrPDB Length = 198 Score = 27.9 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 19/40 (47%), Gaps = 10/40 (25%) Query: 190 QKVTKFMLCAGRWTGGKSTCSGDSGGPLVCN-GVLQGITS 228 + +T+ CAG GDSGG + + G QG+ S Sbjct: 129 RGLTQGNACAG---------RGDSGGSWITSAGQAQGVMS 159 >6HQB-A nrPDB Length = 751 Score = 27.5 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 8/16 (50%), Positives = 8/16 (50%) Query: 142 PTQEPALGTTCYASGW 157 P P G TC SGW Sbjct: 573 PCDGPGRGGTCQVSGW 588 >4FE1-A nrPDB Length = 755 Score = 27.1 bits (59), Expect = 7.2, Method: Composition-based stats. Identities = 8/16 (50%), Positives = 8/16 (50%) Query: 142 PTQEPALGTTCYASGW 157 P P G TC SGW Sbjct: 577 PCDGPGRGGTCQVSGW 592 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.153 0.565 Lambda K H 0.267 0.0470 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,115,312 Number of Sequences: 36641 Number of extensions: 529112 Number of successful extensions: 2643 Number of sequences better than 10.0: 186 Number of HSP's better than 10.0 without gapping: 332 Number of HSP's successfully gapped in prelim test: 23 Number of HSP's that attempted gapping in prelim test: 1085 Number of HSP's gapped (non-prelim): 370 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.1 bits)