BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07275 (575 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4OE4-A nrPDB 1133 0.0 4IDS-A nrPDB 452 e-127 4LGZ-A nrPDB 444 e-125 3V9H-A nrPDB 441 e-124 3QAN-A nrPDB 273 1e-73 3RJL-A nrPDB 269 3e-72 5UR2-A nrPDB 240 1e-63 2J5N-A nrPDB 224 9e-59 5FHZ-A nrPDB 165 6e-41 5AC2-A nrPDB 164 1e-40 5GT6-A nrPDB 162 3e-40 5J77-A nrPDB 160 2e-39 4X2Q-A nrPDB 157 1e-38 5AC0-A nrPDB 155 3e-38 1AG8-A nrPDB 151 7e-37 1O9J-A nrPDB 151 8e-37 5L13-A nrPDB 150 1e-36 4O6R-A nrPDB 146 3e-35 4JZ6-A nrPDB 142 3e-34 4V3F-A nrPDB 141 7e-34 3IWJ-A nrPDB 140 1e-33 5KLK-A nrPDB 139 2e-33 4DNG-A nrPDB 139 4e-33 1BPW-A nrPDB 137 9e-33 4CAZ-A nrPDB 137 1e-32 2D4E-A nrPDB 134 1e-31 4I8P-A nrPDB 133 2e-31 4GO4-A nrPDB 133 2e-31 3PRL-A nrPDB 133 2e-31 4MPY-A nrPDB 132 4e-31 4QYJ-A nrPDB 129 3e-30 3R64-A nrPDB 127 1e-29 4ZZ7-A nrPDB 127 1e-29 6QAO-A nrPDB 126 2e-29 1T90-A nrPDB 126 3e-29 2HG2-A nrPDB 126 3e-29 3I44-A nrPDB 126 3e-29 4PXL-B nrPDB 126 3e-29 3RHD-A nrPDB 125 4e-29 3RHO-A nrPDB 125 4e-29 3R31-A nrPDB 125 5e-29 4F3X-A nrPDB 124 1e-28 4PZ2-A nrPDB 124 1e-28 1WNB-A nrPDB 123 2e-28 3IWK-A nrPDB 123 3e-28 5U0M-A nrPDB 122 3e-28 2QE0-A nrPDB 122 4e-28 4U3W-A nrPDB 122 4e-28 3JZ4-A nrPDB 119 3e-27 4PXN-A nrPDB 118 6e-27 4I8Q-A nrPDB 117 1e-26 6MVR-A nrPDB 116 2e-26 3TY7-A nrPDB 116 3e-26 2JG7-A nrPDB 114 1e-25 5TJR-A nrPDB 113 3e-25 4O5H-A nrPDB 112 5e-25 4X0T-A nrPDB 112 5e-25 3RH9-A nrPDB 111 9e-25 6B4R-B nrPDB 111 1e-24 6FK3-A nrPDB 110 2e-24 5EUY-A nrPDB 109 4e-24 4KNA-A nrPDB 106 2e-23 6C43-A nrPDB 105 5e-23 3JU8-A nrPDB 103 3e-22 3VZ0-A nrPDB 102 4e-22 4V6H-A nrPDB 102 6e-22 3K2W-A nrPDB 100 1e-21 5X5U-A nrPDB 100 2e-21 6DBB-A nrPDB 100 2e-21 3EK1-A nrPDB 99 4e-21 3U4J-A nrPDB 99 5e-21 5IUV-A nrPDB 98 1e-20 4E4G-A nrPDB 98 1e-20 4LIH-A nrPDB 93 3e-19 1UXV-A nrPDB 92 4e-19 3B4W-A nrPDB 92 6e-19 4H7N-A nrPDB 92 8e-19 5VBF-A nrPDB 91 1e-18 3EFV-A nrPDB 89 5e-18 4OGD-A nrPDB 88 9e-18 5N5S-A nrPDB 87 2e-17 4YWE-A nrPDB 87 2e-17 4I3V-A nrPDB 84 1e-16 3VZ3-A nrPDB 82 5e-16 5UCD-A nrPDB 81 1e-15 2W8P-A nrPDB 79 6e-15 3ROS-A nrPDB 79 8e-15 3SZA-A nrPDB 75 1e-13 5JRY-A nrPDB 74 2e-13 5KF0-A nrPDB 70 2e-12 1AD3-A nrPDB 70 3e-12 4QGK-A nrPDB 66 5e-11 5J6B-A nrPDB 65 6e-11 2Y53-A nrPDB 59 5e-09 6D97-A nrPDB 55 7e-08 5NNO-A nrPDB 52 9e-07 5J7I-A nrPDB 46 5e-05 3K9D-A nrPDB 42 5e-04 5UJU-A nrPDB 39 0.009 1O20-A nrPDB 35 0.12 1J39-A nrPDB 33 0.30 4D3Y-A nrPDB 32 0.72 4NOM-A nrPDB 32 0.79 3MY7-A nrPDB 32 0.80 4FGU-A nrPDB 30 2.1 4USR-A nrPDB 30 2.1 5YKB-A nrPDB 30 2.3 5L9W-B nrPDB 28 9.1 >4OE4-A nrPDB Length = 580 Score = 1133 bits (2931), Expect = 0.0, Method: Compositional matrix adjust. Identities = 555/556 (99%), Positives = 556/556 (100%) Query: 20 GHIKPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALF 79 GH+KPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALF Sbjct: 19 GHMKPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALF 78 Query: 80 PQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKY 139 PQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKY Sbjct: 79 PQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKY 138 Query: 140 RYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYR 199 RYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYR Sbjct: 139 RYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYR 198 Query: 200 PLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGV 259 PLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGV Sbjct: 199 PLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGV 258 Query: 260 INFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETG 319 INFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETG Sbjct: 259 INFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETG 318 Query: 320 GKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQN 379 GKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQN Sbjct: 319 GKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQN 378 Query: 380 VVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWF 439 VVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWF Sbjct: 379 VVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWF 438 Query: 440 VGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRK 499 VGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRK Sbjct: 439 VGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRK 498 Query: 500 AIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTK 559 AIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTK Sbjct: 499 AIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTK 558 Query: 560 ENFYELTDFKYPSNYE 575 ENFYELTDFKYPSNYE Sbjct: 559 ENFYELTDFKYPSNYE 574 >4IDS-A nrPDB Length = 563 Score = 452 bits (1162), Expect = e-127, Method: Compositional matrix adjust. Identities = 244/528 (46%), Positives = 329/528 (62%), Gaps = 20/528 (3%) Query: 47 LRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAV 106 LR L +++P VI G + ER Q P H L +T AT D AV Sbjct: 48 LRTELASLADHPIDLPHVIGGRHRMGDGERIDVVQ--PHRHAARLGTLTNATHADAAAAV 105 Query: 107 KAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITEL 166 +AA AK DW LPF +R+A+FL+AADL++ +R + AATMLGQ K+VYQAEID + EL Sbjct: 106 EAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATMLGQSKSVYQAEIDAVCEL 165 Query: 167 SDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL 226 DF+R+ V +A + QQP+ S G WN+ +YRPL+GFVYA++PFNFT+IA NL APAL Sbjct: 166 IDFWRFNVAFARQILEQQPI-SGPGEWNRIDYRPLDGFVYAITPFNFTSIAGNLPTAPAL 224 Query: 227 MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFT 286 MGNTV+WKPS T L+ YL M +LE AGLP GVIN + GD V+D LAD +HFT Sbjct: 225 MGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGFAVSDVALADPRLAGIHFT 284 Query: 287 GSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF 346 GST F L+ + + + G+Y YPR++GETGGK+F + H SA + IRG F++ Sbjct: 285 GSTATFGHLWQWVGTNI--GRYHSYPRLVGETGGKDFVVAHASARPDVLRTALIRGAFDY 342 Query: 347 QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGN---LRGFMGPVI 403 QGQKCSA SR ++ S + ++ A+ + G+ L + G +I Sbjct: 343 QGQKCSAVSRAFIAHSVWQRMGDELL------------AKAAELRYGDITDLSNYGGALI 390 Query: 404 HEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI 463 +++F K V IE AK + + GG+YD S+G+FV PTV+ + P E+FGP+ Sbjct: 391 DQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEYFGPL 450 Query: 464 LTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTG 523 L+V+ YPD + +I D+ID S+YALTGA+ A DR+A+ A ++L+F+AGNFY+NDK TG Sbjct: 451 LSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVNDKPTG 510 Query: 524 AVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELTDFKYP 571 AVV +Q FGGAR S T+DKAG P L R+ S R+ KE F TD YP Sbjct: 511 AVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDHIYP 558 >4LGZ-A nrPDB Length = 563 Score = 444 bits (1141), Expect = e-125, Method: Compositional matrix adjust. Identities = 231/543 (42%), Positives = 331/543 (60%), Gaps = 15/543 (2%) Query: 28 IRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANH 87 + NEP+ F + D L+ +L K + +P V+ E ++ ++ + Q +P NH Sbjct: 32 VANEPILAFSQ-GSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQY---QLSPFNH 87 Query: 88 QQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAAT 147 +A A + + A+ AA A+K+W P DR+ +FLKAAD++S R ++LA T Sbjct: 88 AHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAKT 147 Query: 148 MLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYA 207 M+GQGK V QAEID EL DFFR+ K+A +L +QP+ T N YR LEGFV A Sbjct: 148 MVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPST-NHTVYRGLEGFVAA 206 Query: 208 VSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDP 267 +SPFNFTAI NL GAPALMGN V+WKPS TA L++Y + +L EAGLP +I F+P D Sbjct: 207 ISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266 Query: 268 VQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVH 327 D V + + ++FTGS FK L+ ++ + ++R +PR+ GE GGKNFH VH Sbjct: 267 PTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNL--DRFRTFPRLAGECGGKNFHFVH 324 Query: 328 PSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSA 387 SA++ V T+R FE+ GQKCSA SRLY+P+S + + L+ + + + A Sbjct: 325 SSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRL---LEEHSRIKVGDPA 381 Query: 388 SPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKA 447 + F VI ++F ++ K +E A+ P L IL GGQ ++S G++V P +I++ Sbjct: 382 E-----DFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIES 436 Query: 448 KRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEK 507 K P P M E FGP+LTVY YPD ++ E ++D+T+ Y LTGA+FA+D+ ++ A Sbjct: 437 KDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRM 496 Query: 508 LKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELTD 567 L+ +AGNFYINDK TG+VV QQ FGGAR SGT+DK GGP+ + R+ S + KE L D Sbjct: 497 LRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGD 556 Query: 568 FKY 570 ++Y Sbjct: 557 WRY 559 >3V9H-A nrPDB Length = 566 Score = 441 bits (1134), Expect = e-124, Method: Compositional matrix adjust. Identities = 231/543 (42%), Positives = 328/543 (60%), Gaps = 15/543 (2%) Query: 28 IRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANH 87 + NEPV F + D L+ +L K +P V+ E ++ ++ + Q +P NH Sbjct: 35 VANEPVLAFTQ-GSPERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQY---QVSPFNH 90 Query: 88 QQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAAT 147 +A A + + A++AA A+K+W P DR+ IFLKAAD++S R ++LA T Sbjct: 91 GHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKT 150 Query: 148 MLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYA 207 M+GQGK V QAEID EL DFFR+ KYA +L QQP+ T N YR LEGFV A Sbjct: 151 MVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPST-NSTVYRGLEGFVAA 209 Query: 208 VSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDP 267 +SPFNFTAI NL GAPALMGN V+WKPS TA L++Y + +L EAGLP +I F+P D Sbjct: 210 ISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 269 Query: 268 VQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVH 327 D V + + ++FTGS FK L+ ++ + ++ +PR+ GE GGKNFH VH Sbjct: 270 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNL--DRFHTFPRLAGECGGKNFHFVH 327 Query: 328 PSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSA 387 SA++ V T+R FE+ GQKCSA +RLY+P S + + L+ + + + A Sbjct: 328 RSADVESVVSGTLRSAFEYGGQKCSACARLYVPHSLWPQIKGRL---LEEHSRIKVGDPA 384 Query: 388 SPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKA 447 + F VI +SF ++ K +E A+ P L IL GG+ D S G+FV P ++++ Sbjct: 385 E-----DFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVES 439 Query: 448 KRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEK 507 K P P M E FGP+L+VY YPD ++ E ++D+T+ Y LTGA+F++D+ ++ A + Sbjct: 440 KDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKV 499 Query: 508 LKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELTD 567 L+ +AGNFYINDK TG++V QQ FGGAR SGT+DK GGP+ + R+ S + KE L D Sbjct: 500 LRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGD 559 Query: 568 FKY 570 + Y Sbjct: 560 WSY 562 >3QAN-A nrPDB Length = 538 Score = 273 bits (698), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 177/506 (34%), Positives = 270/506 (53%), Gaps = 25/506 (4%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119 E PL+INGER+ ++ NPA Q++ +V++A + A+++A +A + W N+ Sbjct: 37 EYPLIINGERVTTEDK---IQSWNPARKDQLVGSVSKANQDLAEKAIQSADEAFQTWRNV 93 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 +R+ I +KAA +I + +++ A + GK +A+ D E DF YY + + Sbjct: 94 NPEERANILVKAAAIIRRR-KHEFSAWLVHEAGKPWKEADADT-AEAIDFLEYYARQMIE 151 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFT-AIAANLIGAPALMGNTVVWKPSQT 238 L + + S G N+ Y P+ G +SP+NF AI AP + GNTVV KP+ T Sbjct: 152 LNRGKEILSRPGEQNRYFYTPM-GVTVTISPWNFALAIMVGTAVAPIVTGNTVVLKPAST 210 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 + + VLE+AGLPKGVIN++PG +V D ++ + FTGS +V LY + Sbjct: 211 TPVVAAKFVEVLEDAGLPKGVINYVPGSGAEVGDYLVDHPKTSLITFTGSKDVGVRLYER 270 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 + VV R+I E GGK+ +V A++ A S + F F GQKCSA SR Sbjct: 271 --AAVVRPGQNHLKRVIVEMGGKDTVVVDRDADLDLAAESILVSAFGFSGQKCSAGSRAV 328 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + + +E L + ++ V P + N +MGPVI E++F+K++ IE Sbjct: 329 IHKDVYDEVLEKTVALAKNLTV------GDPTNRDN---YMGPVIDEKAFEKIMSYIEIG 379 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 KK+ L + GG+ D S G+F+ PT+I P+ M E FGP++ + D F+ Sbjct: 380 KKEGRL--MTGGEGDSSTGFFIQPTIIADLDPEAVIMQEEIFGPVVAFSKAND--FDHAL 435 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 +I +NT +Y LTGA+ ++R IE A K +F GN Y N CTGA+V FGG +MSG Sbjct: 436 EIANNT-EYGLTGAVITRNRAHIEQA--KREFHVGNLYFNRNCTGAIVGYHPFGGFKMSG 492 Query: 539 TDDKAGGPNILSRFVSIRNTKENFYE 564 TD KAGGP+ L+ + + E + E Sbjct: 493 TDSKAGGPDYLALHMQAKTVSEMYAE 518 >3RJL-A nrPDB Length = 538 Score = 269 bits (687), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 177/507 (34%), Positives = 264/507 (52%), Gaps = 31/507 (6%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPF 121 PLVI+GER N+ NPAN ++V+ V++AT+ A++AA A + W Sbjct: 39 PLVIDGERYETENK---IVSINPANKEEVVGTVSKATQDHAEKAIQAAAKAFETWRYTDP 95 Query: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY 181 +R+A+ +A + K +++ A + GK +A+ D E DF YY + +L Sbjct: 96 EERAAVLFRAVAKVRRK-KHEFSALLVKEAGKPWNEADADT-AEAIDFMEYYARQMIELA 153 Query: 182 AQQPVESADGTWNKAEYRPLEGFVYAVSPFNFT-AIAANLIGAPALMGNTVVWKPSQTAA 240 +PV S +G N+ Y P G + P+NF AI A AP + GNTVV KP+ A Sbjct: 154 KGKPVNSREGERNQYVYTPT-GVTVVIPPWNFLFAIMAGTTVAPIVTGNTVVLKPASAAP 212 Query: 241 LSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY---G 297 + + VLEE+GLPKGV+NF+PG +V D ++ + FTGS V ++ Sbjct: 213 VIAAKFVEVLEESGLPKGVVNFVPGSGAEVGDYLVDHPKTSIITFTGSREVGTRIFERAA 272 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 K+Q G K ++I E GGK+ +V +I A S F F GQKCSA SR Sbjct: 273 KVQPGQTHLK-----QVIAEMGGKDTVVVDEDCDIELAAQSIFTSAFGFAGQKCSAGSRA 327 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 + E +E L + I +S+ V +++ +MGPVI + SF+K++ IE Sbjct: 328 VVHEKVYDEVLKRVIEITESKKVGEPDSADV---------YMGPVIDQASFNKIMDYIEI 378 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 K++ L + GG+ D S+G+F+ PT+ P M E FGP++ + + F+E Sbjct: 379 GKEEGRL--VSGGKGDDSKGYFIEPTIFADLDPKARLMQEEIFGPVVAFSKV--SSFDEA 434 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 ++ +NT +Y LTGA+ K+R I A K +F GN Y N CTGA+V FGG +MS Sbjct: 435 LEVANNT-EYGLTGAVITKNRDHINRA--KQEFHVGNLYFNRNCTGAIVGYHPFGGFKMS 491 Query: 538 GTDDKAGGPNILSRFVSIRNTKENFYE 564 GTD KAGGP+ L+ + + E F E Sbjct: 492 GTDSKAGGPDYLALHMQAKTISEMFAE 518 >5UR2-A nrPDB Length = 984 Score = 240 bits (613), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 170/540 (31%), Positives = 281/540 (52%), Gaps = 27/540 (5%) Query: 23 KPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQT 82 K P NEP+ F + +L+A S + V +VIN + + +F + Sbjct: 460 KKPGKFYNEPLLDFA-VKADREKMLKALAEAKASLPVNVNIVINNKELQSGK---IFDRV 515 Query: 83 NPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYD 142 NP+ Q++ + AT + A++AA+ A K W N+P R+A+ K AD++ T+ R+ Sbjct: 516 NPSQSDQIVGKIQMATTEQAEQAMQAAQTAYKTWKNVPCEQRAALVDKLADIM-TRDRFK 574 Query: 143 MLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLE 202 ++A +L GK +A+ D I E DF RYY ++ +L V G + Y+ Sbjct: 575 LIATQVLEVGKPWAEADGD-IGEAIDFCRYYARHMRELQKPLRVGGLPGELSHYIYKS-R 632 Query: 203 GFVYAVSPFNF-TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVIN 261 G ++P+NF AI A ++ A A+ GNTVV KP++ + + + LM +++EAG P+GVIN Sbjct: 633 GVTAVIAPWNFPLAILAGMVTAAAVAGNTVVMKPAEQSTVVAWGLMKMIQEAGFPQGVIN 692 Query: 262 FIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGK 321 F+PG +V + ++ K + FTGS V L+ ++ VV+ + R I E GGK Sbjct: 693 FLPGYGEEVGEYIVNHKYTTTIAFTGSKAV--GLHIMNRAAVVQPGQQHVKRCIIEMGGK 750 Query: 322 NFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV 381 N ++ A++ AV I F F GQKCSAASR+ + + + F+ + +S + Sbjct: 751 NAVIIDNDADLDEAVDGVIYSAFGFSGQKCSAASRVIVLDEVYDRFVDRLVETAKSIEIH 810 Query: 382 PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVG 441 P N + +MGPV+ ++++D+++ I +A+K+ +L L+ G G+F Sbjct: 811 PAE---------NPKAYMGPVVDKEAYDRILGTIAEAEKNHKL--LFKGSV-PGGGFFAP 858 Query: 442 PTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAI 501 PT+ D E FGP++ V + ++ DI N+++YALTG +F++ I Sbjct: 859 PTIFGDVPGDAKLAQAEIFGPVVAVIRAKN--LDQALDIA-NSTEYALTGGVFSRSPANI 915 Query: 502 EYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKEN 561 E+L+ GN Y+N TGA+V + FGG +MSG K GGP+ L +++ EN Sbjct: 916 NRVKEELE--VGNLYVNRGITGAMVDRHPFGGFKMSGIGSKTGGPDYLKQYMEPACVTEN 973 >2J5N-A nrPDB Length = 516 Score = 224 bits (570), Expect = 9e-59, Method: Compositional matrix adjust. Identities = 170/540 (31%), Positives = 270/540 (50%), Gaps = 36/540 (6%) Query: 29 RNEPVKPFRNIDLKDWDLLRASLMKFKSS-SLEVPLVINGERIYDNNERALFPQTNPANH 87 RNEP++ F+ + + +R +L + + PL I GE + D ER + NP+ Sbjct: 7 RNEPIETFQTEEARR--AMREALRRVREEFGRHYPLYIGGEWV-DTKERMV--SLNPSAP 61 Query: 88 QQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAAT 147 +V+ +A + + A++AA A K W + P DRS + LKAA L+ + R ++ A Sbjct: 62 SEVVGTTAKAGKAEAEAALEAAWKAFKTWKDWPQEDRSRLLLKAAALMRRRKR-ELEATL 120 Query: 148 MLGQGKNVYQAEIDCITELSDFFRYYVKYASDL-YAQQPVESADGTWNKAEYRPLEGFVY 206 + GKN +A D + E DF YY + A Y V G N++ Y PL G Sbjct: 121 VYEVGKNWVEASAD-VAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYVPL-GAGV 178 Query: 207 AVSPFNF-TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPG 265 ++P+NF AI +I P +GNTV+ KP++ A + + + EAG P GV+NF+PG Sbjct: 179 VIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPG 238 Query: 266 DPVQVTDQVLADKDFGALHFTGSTNVFKSLY---GKIQSGVVEGKYRDYPRIIGETGGKN 322 +V ++ ++FTGS V +Y G++ G + R ETGGK+ Sbjct: 239 VGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAAGRLAPGQTW-----FKRAYVETGGKD 293 Query: 323 FHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVP 382 +V +A+ A + + FQGQKCSAASRL L + E L + + +V P Sbjct: 294 AIIVDETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVGP 353 Query: 383 MNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGP 442 + +GPV+ + K++ IE K + +L + GG+ + +G+F+ P Sbjct: 354 AEENPD----------LGPVVSAEQERKVLSYIEIGKNEGQL--VLGGKRLEGEGYFIAP 401 Query: 443 TVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIE 502 TV P E FGP+L+V D F E ++ ++T Y LTG ++++ R+ +E Sbjct: 402 TVFTEVPPKARIAQEEIFGPVLSVIRVKD--FAEALEVANDTP-YGLTGGVYSRKREHLE 458 Query: 503 YADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENF 562 +A + +F GN Y N K TGA+V Q FGG ++SGT+ K G + L F+ ++ E F Sbjct: 459 WA--RREFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMKAVAERF 516 >5FHZ-A nrPDB Length = 529 Score = 165 bits (417), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 150/495 (30%), Positives = 234/495 (47%), Gaps = 56/495 (11%) Query: 69 RIYDNNE------RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA---KKDWYNL 119 +I+ NNE F NP+ +Q+ V + + DV AV+AA+ A W L Sbjct: 50 KIFINNEWHESKSGKKFATCNPSTREQI-CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 108 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAE-ID---CITELSDFFRYYVK 175 R + + ADL+ + R + A + GK A ID CI L RY+ Sbjct: 109 DALSRGRLLHQLADLVE-RDRATLAALETMDTGKPFLHAFFIDLEGCIRTL----RYFAG 163 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWK 234 +A + + + + D + P+ G A++P+NF + APAL GNT+V K Sbjct: 164 WADKIQGKT-IPTDDNVVCFTRHEPI-GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 221 Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKS 294 P++ L+ L ++++EAG P GV+N +PG V + + + FTGST V Sbjct: 222 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEV--- 278 Query: 295 LYGKIQSGVVEGKYR-DYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 GK+ V E R + R+ E GGKN +V A++ AV +G F QGQ C+A Sbjct: 279 --GKL---VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTA 333 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 ASR+++ E EF + +S P +++ GP I ++ FDK+++ Sbjct: 334 ASRVFVEEQVYSEF------VRRSVEYAKKRPVGDPF---DVKTEQGPQIDQKQFDKILE 384 Query: 414 VIEDAKKD-PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 +IE KK+ +LE GG + +G F+ PTV + E FGP+ P Sbjct: 385 LIESGKKEGAKLEC--GGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPV-----QPIL 437 Query: 473 EFNEICDIID--NTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVVSQQ 529 +F I ++I N++ Y LT A+F K+ KA++ A +G +IN C A+ +Q Sbjct: 438 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLAS---ALESGTVWIN--CYNALYAQA 492 Query: 530 WFGGARMSGTDDKAG 544 FGG +MSG + G Sbjct: 493 PFGGFKMSGNGRELG 507 >5AC2-A nrPDB Length = 501 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 152/499 (30%), Positives = 237/499 (47%), Gaps = 52/499 (10%) Query: 63 LVINGERIYDNNE------RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA---K 113 L I +I+ NNE FP NPA ++ L V + ++DV AVKAA+ A Sbjct: 16 LKIQYTKIFINNEWHDSVSGKKFPVFNPATEEE-LCQVEEGDKEDVDKAVKAARQAFQIG 74 Query: 114 KDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM--LGQGKNVYQAEIDCITELSDFFR 171 W + +R + K ADLI R +L ATM + GK A ++ + R Sbjct: 75 SPWRTMDASERGRLLYKLADLIE---RDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLR 131 Query: 172 YYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGN 229 Y +A + + P++ T+ + E P+ G + P+NF + PAL GN Sbjct: 132 YCAGWADKIQGRTIPIDGNFFTYTRHE--PI-GVCGQIIPWNFPLVMLIWKIGPALSCGN 188 Query: 230 TVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGST 289 TVV KP++ L+ + ++++EAG P GV+N +PG + + D + FTGST Sbjct: 189 TVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGST 248 Query: 290 NVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQ 349 V K + K +G + R+ E GGK+ +V A++ +AV G F QGQ Sbjct: 249 EVGKLI--KEAAG-----KSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQ 301 Query: 350 KCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFD 409 C AASR+++ ES +EF + +S +P++ G + GP I ++ +D Sbjct: 302 CCIAASRIFVEESIYDEF------VRRSVERAKKYILGNPLTPGVTQ---GPQIDKEQYD 352 Query: 410 KLVKVIEDAKKD-PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYE 468 K++ +IE KK+ +LE GG ++G+FV PTV + E FGP+ + Sbjct: 353 KILDLIESGKKEGAKLEC--GGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIM- 409 Query: 469 YPDTEFNEICDIID--NTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAV 525 +F + D+I N + Y L+ +F KD KAI + AG ++N C G V Sbjct: 410 ----KFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISS---ALQAGTVWVN--CYGVV 460 Query: 526 VSQQWFGGARMSGTDDKAG 544 +Q FGG +MSG + G Sbjct: 461 SAQCPFGGFKMSGNGRELG 479 >5GT6-A nrPDB Length = 508 Score = 162 bits (411), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 141/494 (28%), Positives = 229/494 (46%), Gaps = 45/494 (9%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD--WY 117 E+ + INGE + + F NPA + VLA V +A E+D+ AVKAA+ A + W Sbjct: 33 EIKMFINGEFVSAIGGKT-FETYNPAT-EDVLAVVCEAQEEDIDAAVKAARSAFESGPWA 90 Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA 177 + +R+ + K ADLI ++R ++ L GK A D I+ + +RYY + Sbjct: 91 EMTTAERAHLIYKLADLIE-EHREELAQLEALDNGKPYQVALDDDISATVENYRYYAGWT 149 Query: 178 SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANL-IGAPALMGNTVVWKPS 236 + + Q S D N + P+ G V + P+NF + ++ +GA G T+V KP+ Sbjct: 150 TKIIGQTIPISKD-YLNYTRHEPV-GVVGQIIPWNFPLVMSSWKMGAALATGCTIVLKPA 207 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + LS + +EAG P GV+NF+PG + ++ D + FTGST Sbjct: 208 EQTPLSLLYAAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDKVAFTGST------- 260 Query: 297 GKIQSGVVEGKY--RDYPRIIG----ETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQK 350 V GKY R +I E GGK+ +++ A++ A+ +G GQ Sbjct: 261 -------VTGKYIMRQSAEMIKHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQN 313 Query: 351 CSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDK 410 CSA SR+++ E + + V M + +G MGP++ ++ ++ Sbjct: 314 CSAGSRVFVHRKHYETVVDAL---------VKMANNVKLGAGMEKETEMGPLVSKKQQER 364 Query: 411 LVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP 470 ++ IE KK+ + GG+ +G+FV PTV D + E FGP++ V + Sbjct: 365 VLNYIEQGKKEGAT-VAAGGERALEKGYFVKPTVFTDVTDDMTIVKEEIFGPVVVVLPFD 423 Query: 471 DTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW 530 TE E+ + +N+S Y L ++ ++ K KLK AG +IND + Sbjct: 424 STE--EVIERANNSS-YGLAAGVWTQNIKTGHQVANKLK--AGTVWINDYNLENAAAP-- 476 Query: 531 FGGARMSGTDDKAG 544 FGG + SG + G Sbjct: 477 FGGYKQSGIGRELG 490 >5J77-A nrPDB Length = 508 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 140/478 (29%), Positives = 225/478 (47%), Gaps = 43/478 (8%) Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM 148 QV+ + AT DV A+ AA+DA W +L +RS I +A +LI K R ++ M Sbjct: 29 QVIGRMEAATRDDVDRAIDAAEDAFWAWNDLGSVERSKIIYRAKELIE-KNRAELENIIM 87 Query: 149 LGQGKNVYQA--EIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVY 206 GK V +A E+D + D +YY ++A L + VE +Y+ G V Sbjct: 88 EENGKPVKEAKEEVDGVI---DQIQYYAEWARKLNGEV-VEGTSSHRKIFQYKVPYGIVV 143 Query: 207 AVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPG 265 A++P+NF A APAL+ GNTVV KPS S ++ EAG+PKGV+NFI G Sbjct: 144 ALTPWNFPAGMVARKLAPALLTGNTVVLKPSSDTPGSAEWIVRKFVEAGVPKGVLNFITG 203 Query: 266 DPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHL 325 ++ D ++ K + TGST + + K + + ++I E GGK + Sbjct: 204 RGSEIGDYIVEHKKVNLITMTGSTATGQRIMQKASANMA--------KLILELGGKAPFM 255 Query: 326 VHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV-PMN 384 V A++ +A+ + + + GQ C AA RLY+ E + F+S + + + P N Sbjct: 256 VWKDADMDNALKTLLWAKYWNAGQSCIAAERLYVHEDIYDTFMSRFVELSRKLALGDPKN 315 Query: 385 TSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDK-----SQGWF 439 MGP+I++ + +++E+A K+ +IL+GG G+F Sbjct: 316 AD------------MGPLINKGALQATSEIVEEA-KESGAKILFGGSQPSLSGPYRNGYF 362 Query: 440 VGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRK 499 PT+I E F P++ + E E+ D+ N ++Y L +F KD Sbjct: 363 FLPTIIGNADQKSKIFQEEIFAPVIGARKISSVE--EMYDLA-NDNKYGLASYLFTKDPN 419 Query: 500 AIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRN 557 I A E+++F G Y+N G SQ + G RM+G + G +S ++ ++N Sbjct: 420 IIFEASERIRF--GELYVN--MPGPEASQGYHTGFRMTGQAGE-GSKYGISEYLKLKN 472 >4X2Q-A nrPDB Length = 504 Score = 157 bits (397), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 151/500 (30%), Positives = 236/500 (47%), Gaps = 54/500 (10%) Query: 63 LVINGERIYDNNE------RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA---K 113 L I +I+ NNE +FP NPA +QV V +A + D+ AV+AA+ A Sbjct: 19 LEIKYTKIFINNEWQNSESGRVFPVYNPATGEQV-CEVQEADKADIDKAVQAARLAFSLG 77 Query: 114 KDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM--LGQGKNVYQAEIDCITELSDFFR 171 W + +R + K ADL+ R + ATM L GK QA + + FR Sbjct: 78 SVWRRMDASERGRLLDKLADLVE---RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFR 134 Query: 172 YYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GN 229 YY +A ++ PV+ T+ + E P+ G + P+NF + APAL GN Sbjct: 135 YYAGWADKIHGMTIPVDGDYFTFTRHE--PI-GVCGQIIPWNFPLLMFAWKIAPALCCGN 191 Query: 230 TVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGST 289 TVV KP++ LS + +++EAG P GVIN +PG + + + FTGST Sbjct: 192 TVVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGST 251 Query: 290 NVFKSLYGKIQSGVVEGKYR-DYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQG 348 V GK+ + E R + R+ E GGK+ +++ A++ +AV +G F QG Sbjct: 252 EV-----GKL---IQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQG 303 Query: 349 QKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSF 408 Q C+A SR+++ ES EEF + +S SP + GP I ++ + Sbjct: 304 QCCTAGSRIFVEESIYEEF------VRRSVERAKRRVVGSPFDPTTEQ---GPQIDKKQY 354 Query: 409 DKLVKVIEDA-KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVY 467 +K++++I+ + +LE GG+ +G+F+ PTV D E FGP+ + Sbjct: 355 NKILELIQSGVAEGAKLEC--GGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEIL 412 Query: 468 EYPDTEFNEICDIID--NTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGA 524 F + ++I+ N S + L A+F D KA+ + AG +IN C A Sbjct: 413 -----RFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSS---AMQAGTVWIN--CYNA 462 Query: 525 VVSQQWFGGARMSGTDDKAG 544 + +Q FGG +MSG + G Sbjct: 463 LNAQSPFGGFKMSGNGREMG 482 >5AC0-A nrPDB Length = 501 Score = 155 bits (393), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 152/497 (30%), Positives = 238/497 (47%), Gaps = 60/497 (12%) Query: 69 RIYDNNE------RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA---KKDWYNL 119 +I+ NNE FP NPA ++ L V + ++DV AVKAA+ A W + Sbjct: 22 KIFINNEWHSSVSGKKFPVFNPATEEK-LCEVEEGDKEDVDKAVKAARQAFQIGSPWRTM 80 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATM--LGQGK---NVYQAEID-CITELSDFFRYY 173 +R + K ADLI R +L ATM + GK N Y ++ CI L RY Sbjct: 81 DASERGRLLNKLADLIE---RDRLLLATMEAMNGGKLFSNAYLMDLGGCIKTL----RYC 133 Query: 174 VKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTV 231 +A + + P++ T+ ++E P+ G + P+NF + PAL GNTV Sbjct: 134 AGWADKIQGRTIPMDGNFFTYTRSE--PV-GVCGQIIPWNFPLLMFLWKIGPALSCGNTV 190 Query: 232 VWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNV 291 V KP++ L+ + ++++EAG P GV+N +PG + + D + FTGST V Sbjct: 191 VVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEV 250 Query: 292 FKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKC 351 K + K +G + R+ E GGK+ +V A++ +AV +G F QGQ C Sbjct: 251 GKLI--KEAAG-----KSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCC 303 Query: 352 SAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKL 411 AASRL++ ES +EF+ + +++ V N +S GP I ++ ++K+ Sbjct: 304 IAASRLFVEESIYDEFVRR--SVERAKKYVLGNPLTPGVS-------QGPQIDKEQYEKI 354 Query: 412 VKVIEDAKKD-PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP 470 + +IE KK+ +LE GG ++G+F+ PTV D E FGP+ + Sbjct: 355 LDLIESGKKEGAKLEC--GGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIM--- 409 Query: 471 DTEFNEICDIID--NTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVVS 527 +F + D+I N + Y L+ IF D KAI + +G ++N C V + Sbjct: 410 --KFKSLDDVIKRANNTFYGLSAGIFTNDIDKAITVSS---ALQSGTVWVN--CYSVVSA 462 Query: 528 QQWFGGARMSGTDDKAG 544 Q FGG +MSG + G Sbjct: 463 QCPFGGFKMSGNGRELG 479 >1AG8-A nrPDB Length = 499 Score = 151 bits (382), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 137/489 (28%), Positives = 223/489 (45%), Gaps = 44/489 (8%) Query: 69 RIYDNNE------RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA---KKDWYNL 119 +I+ NNE + FP NP+ V+ +V + + DV AVKAA+ A W + Sbjct: 20 QIFINNEWHDAVSKKTFPTVNPSTGD-VICHVAEGDKADVDRAVKAARAAFQLGSPWRRM 78 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNV---YQAEIDCITELSDFFRYYVKY 176 +R + + ADLI Y + A L GK Y ++D + + RYY + Sbjct: 79 DASERGRLLNRLADLIERDRTY-LAALETLDNGKPYIISYLVDLDMVLKC---LRYYAGW 134 Query: 177 ASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKP 235 A D Y + + ++ + P+ G + P+NF + PAL GN VV K Sbjct: 135 A-DKYHGKTIPIDGDYFSYTRHEPV-GVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKV 192 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 ++ L+ + +++EAG P GV+N IPG + + +D + FTGST V + Sbjct: 193 AEQTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLI 252 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAAS 355 V GK + R+ E GGK+ +++ A++ AV F QGQ C A S Sbjct: 253 Q------VAAGK-SNLKRVTLEIGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGS 305 Query: 356 RLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415 R ++ E EF+ +S+ V +P + R GP + E F K++ I Sbjct: 306 RTFVQEDIYAEFVERSVARAKSRVV------GNPF---DSRTEQGPQVDETQFKKVLGYI 356 Query: 416 EDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 + K++ L++L GG +G+F+ PTV + E FGP++ + ++ E Sbjct: 357 KSGKEE-GLKLLCGGGAAADRGYFIQPTVFGDLQDGMTIAKEEIFGPVMQILKFKSME-- 413 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 E+ +N S+Y L A+F KD Y + L+ AG ++N C +Q FGG + Sbjct: 414 EVVGRANN-SKYGLAAAVFTKDLDKANYLSQALQ--AGTVWVN--CYDVFGAQSPFGGYK 468 Query: 536 MSGTDDKAG 544 +SG+ + G Sbjct: 469 LSGSGRELG 477 >1O9J-A nrPDB Length = 501 Score = 151 bits (381), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 148/508 (29%), Positives = 238/508 (46%), Gaps = 59/508 (11%) Query: 59 LEVPLV---INGERIYDNNE------RALFPQTNPANHQQVLANVTQATEKDVMNAVKAA 109 L PL I +++ NNE FP NPA +++ V +A ++DV AVKAA Sbjct: 9 LPAPLTNIKIQHTKLFINNEWHESVSGKTFPVFNPATEEKI-CEVEEADKEDVDKAVKAA 67 Query: 110 KDA---KKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM--LGQGK---NVYQAEID 161 ++A W + +R + K ADLI R +L AT+ + GK + Y ++D Sbjct: 68 REAFQMGSPWRTMDASERGQLIYKLADLIE---RDRLLLATLESINAGKVFASAYLMDLD 124 Query: 162 -CITELSDFFRYYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIA-A 218 CI L RY +A + + PV+ ++ + E + G ++ P+N I A Sbjct: 125 YCIKAL----RYCAGWADKIQGRTIPVDGEFFSYTRHEPIGVCGLIF---PWNAPMILLA 177 Query: 219 NLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK 278 IG GNTV+ KP++ L+ + ++++EAG P GV+N +PG + + Sbjct: 178 CKIGPALCCGNTVIVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHM 237 Query: 279 DFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLS 338 D + FTGST V K IQ + + R+ E G KN +V A++ AV Sbjct: 238 DVDKVAFTGSTEVGK----MIQEAAAKSNLK---RVTLELGAKNPCIVFADADLDSAVEF 290 Query: 339 TIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGF 398 +G F QGQ C AAS+L++ E+ +EF+ +S +P++ G Sbjct: 291 AHQGVFTNQGQSCIAASKLFVEEAIYDEFVQ------RSVERAKKYVFGNPLTPGVNH-- 342 Query: 399 MGPVIHEQSFDKLVKVIEDAKKD-PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMST 457 GP I++ +K++++IE KK+ +LE GG ++G+F+ PTV D Sbjct: 343 -GPQINKAQHNKIMELIESGKKEGAKLEC--GGGPWGNKGYFIQPTVFSNVTDDMRIAKE 399 Query: 458 EFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFY 516 E FGP+ + ++ +E+ +NT Y L +F KD KA+ + AG + Sbjct: 400 EIFGPVQQIMKF--KSLDEVIKRANNT-YYGLVAGVFTKDLDKAVTVSS---ALQAGTVW 453 Query: 517 INDKCTGAVVSQQWFGGARMSGTDDKAG 544 +N C A +Q GG +MSG + G Sbjct: 454 VN--CYLAASAQSPAGGFKMSGHGREMG 479 >5L13-A nrPDB Length = 517 Score = 150 bits (379), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 133/490 (27%), Positives = 219/490 (44%), Gaps = 46/490 (9%) Query: 69 RIYDNNE------RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA---KKDWYNL 119 +I+ NNE R FP NP+ + V+ V + ++DV AVKAA+ A W + Sbjct: 38 QIFINNEWHDAVSRKTFPTVNPSTGE-VICQVAEGDKEDVDKAVKAARAAFQLGSPWRRM 96 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNV---YQAEIDCITELSDFFRYYVKY 176 R + + ADLI Y + A L GK Y ++D + + RYY + Sbjct: 97 DASHRGRLLNRLADLIERDRTY-LAALETLDNGKPYVISYLVDLDMVLKC---LRYYAGW 152 Query: 177 ASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKP 235 A D Y + + ++ + P+ G + P+NF + PAL GN VV K Sbjct: 153 A-DKYHGKTIPIDGDFFSYTRHEPV-GVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKV 210 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 ++ L+ + +++EAG P GV+N +PG + + +D + FTGST + + + Sbjct: 211 AEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVI 270 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAAS 355 V + R+ E GGK+ +++ A++ AV F QGQ C A S Sbjct: 271 Q-------VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGS 323 Query: 356 RLYLPESKSEEFLSDMFGILQSQNVV-PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKV 414 R ++ E +EF+ +S+ V P ++ GP + E F K++ Sbjct: 324 RTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTE----------QGPQVDETQFKKILGY 373 Query: 415 IEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEF 474 I K++ ++L GG +G+F+ PTV + E FGP++ + ++ E Sbjct: 374 INTGKQEGA-KLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIE- 431 Query: 475 NEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGA 534 E+ +N S Y L A+F KD Y + L+ AG ++N C +Q FGG Sbjct: 432 -EVVGRANN-STYGLAAAVFTKDLDKANYLSQALQ--AGTVWVN--CYDVFGAQSPFGGY 485 Query: 535 RMSGTDDKAG 544 +MSG+ + G Sbjct: 486 KMSGSGRELG 495 >4O6R-A nrPDB Length = 496 Score = 146 bits (368), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 135/494 (27%), Positives = 213/494 (43%), Gaps = 41/494 (8%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 ++ L I+G R D +R NP + V+ + AT DV AV AA A W Sbjct: 9 MQTQLFIDG-RFVDAVDRGTIDVLNP-HDGSVITKIAAATAADVDLAVDAATRAFPAWSA 66 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 +P +R + L+ AD I + L G + + + + FRY+ A Sbjct: 67 MPAAERGRLLLRLADAIEANTEA-LAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMAD 125 Query: 179 DLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPS 236 L PV++ G N + P+ G V + P+NF + + PAL GNTVV KPS Sbjct: 126 KLQGSVIPVDT--GFLNYVQRAPI-GVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPS 182 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + LS ++ ++ E G P GV+N +PG ++ G + FTGST + Sbjct: 183 EITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRR-- 240 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 +VE + R+ E GGK ++V AN+ A+ F QGQ C A SR Sbjct: 241 ------IVEASQGNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSR 294 Query: 357 LYLPESKSEEFLSDMFGILQSQNVV-PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415 L L E ++ FL + S + P++ + MGP+ +Q D+++ + Sbjct: 295 LVLHERIADAFLERFVALASSIRIGNPLDPNTE----------MGPLTSKQHLDRVLSYV 344 Query: 416 EDAKKDPELEILYGGQYDK----SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPD 471 D ++ +L GG + + G++V PT+++AK E FGP +TV + Sbjct: 345 -DVAREQGGRVLTGGSAPQDPALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGS 403 Query: 472 TEFNEICDIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW 530 ++ I N ++Y L ++ D +A A + AG +IN C V Sbjct: 404 ---DDEALAIANATEYGLGSGLWTNDLSRAHRMA---ARIDAGMCWIN--CYKRVNPGSP 455 Query: 531 FGGARMSGTDDKAG 544 FGG SG + G Sbjct: 456 FGGVGKSGYGREMG 469 >4JZ6-A nrPDB Length = 500 Score = 142 bits (359), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 133/495 (26%), Positives = 246/495 (49%), Gaps = 57/495 (11%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 ++ L IN I D++++ F + +P + +V+ AT D + A +AA++A K W + Sbjct: 18 MKTKLFINNAWI-DSSDQQTFERKHPVS-SEVMTESANATVTDAIKAAQAAEEAFKTWKD 75 Query: 119 LPFYDRSAIFLKAADLISTKYR--YDMLA----ATMLGQGKNVYQAEIDCITELSDFFRY 172 + +R + LK AD++ +K +++A A+ L G NV+ + ++ FR Sbjct: 76 VGPSERRRLLLKVADVMESKTPKFIEVMAMEVGASALWAGFNVHAS--------ANVFRE 127 Query: 173 YVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAI-AANLIGAPALMGNT 230 A+ + + P + A+ T + +P+ G + ++ P+N TA+ AA I P + GNT Sbjct: 128 AASLATQIQGETIPTDKAE-TLSMTLRQPV-GPILSIVPWNGTAVLAARAIAYPLVCGNT 185 Query: 231 VVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDP---VQVTDQVLADKDFGALHFTG 287 VV+K S+ + ++ L+ ++EAGLP GV+N++ P ++ D +++ K+ ++FTG Sbjct: 186 VVFKGSEFSPATHALITQCVQEAGLPAGVLNYLNSSPDRSPEIADALISAKEIRRINFTG 245 Query: 288 STNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQ 347 ST ++ S + + + R + E GGK+ +V A+I+ AV + + G+F FQ Sbjct: 246 ST--------RVGSIIAQKAAQHLKRCLLELGGKSPLIVLDDADINAAVKAAVFGSFLFQ 297 Query: 348 GQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQS 407 GQ C + RL + E ++EF++ + +V P G+ +GP++ S Sbjct: 298 GQICMSTERLVVDEKIADEFVARFVEKTERLSV------GDPCLTGDC--IIGPMVSPNS 349 Query: 408 FDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVY 467 +++ + +DA D +++ GG +QG + T++ + D E FGPI TV Sbjct: 350 GERINGLFKDA-IDKGAKVVCGGM---AQGAVMPATILDHVKSDMRIYDEETFGPI-TVV 404 Query: 468 EYPDTEFNEICDIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVV 526 E I I N S Y L+ +F +D +A+ + G +IN G+ V Sbjct: 405 IRCKGEAEAI--RIANDSVYGLSSGVFGRDINRALRVG---MSIEYGCVHIN----GSTV 455 Query: 527 ---SQQWFGGARMSG 538 +Q +GG + +G Sbjct: 456 QNEAQAPYGGTKNTG 470 >4V3F-A nrPDB Length = 497 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 135/483 (27%), Positives = 222/483 (45%), Gaps = 36/483 (7%) Query: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA--KKDWYNLP 120 L I+GE + ++ P NP+ ++++ ++ AT +DV AV AA+ A + +W Sbjct: 10 LFIDGEW-REPIKKNRIPVINPST-EEIIGDIPAATAEDVEVAVVAARRAFRRNNWSATS 67 Query: 121 FYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 R A +L+A T+ + + + GK +A +D I +++ F Y+ A L Sbjct: 68 GAHR-ATYLRAIAAKITEKKDHFVKLETIDSGKPFDEAVLD-IDDVASCFEYFAGQAEAL 125 Query: 181 YAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 +Q PV + R G V +SP+N+ + A APAL G T V KPS+ Sbjct: 126 DGKQKAPVTLPMERFKSHVLRQPLGVVGLISPWNYPLLMATWKIAPALAAGCTAVLKPSE 185 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 A+++ V E GLP GV+N + G +++ D + FTGS+ Sbjct: 186 LASVTCLEFGEVCNEVGLPPGVLNILTGLGPDAGAPLVSHPDVDKIAFTGSSAT------ 239 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 S V+ + + E GGK+ +V +I V TI G F GQ CSA SRL Sbjct: 240 --GSKVMASAAQLVKPVTLELGGKSPIVVFEDVDIDKVVEWTIFGCFWTNGQICSATSRL 297 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 + ES + EF+ + ++ + + P G +GPVI + +DK++K I Sbjct: 298 LVHESIAAEFVDKLVKWTKNIKI------SDPFEEGCR---LGPVISKGQYDKIMKFIST 348 Query: 418 AKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 AK + ILYGG + +G+++ PT++ E FGP+L V + +E Sbjct: 349 AKSE-GATILYGGSRPEHLKKGYYIEPTIVTDISTSMQIWKEEVFGPVLCVKTF-SSEDE 406 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 I + N ++Y L A+F+ D + E + L+ G ++N C+ Q +GG + Sbjct: 407 AIA--LANDTEYGLAAAVFSNDLERCERITKALE--VGAVWVN--CSQPCFVQAPWGGIK 460 Query: 536 MSG 538 SG Sbjct: 461 RSG 463 >3IWJ-A nrPDB Length = 503 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 141/513 (27%), Positives = 235/513 (45%), Gaps = 42/513 (8%) Query: 63 LVINGE-RIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA-----KKDW 116 L ING+ + N+R P NPA Q ++ ++ AT++DV AV AAK A DW Sbjct: 10 LFINGDWKAPVLNKR--IPVINPAT-QNIIGDIPAATKEDVDVAVAAAKTALTRNKGADW 66 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 R A +L+A T+ + ++ + GK + +A D I +++ F YY Sbjct: 67 ATASGAVR-ARYLRAIAAKVTEKKPELAKLESIDCGKPLDEAAWD-IDDVAGCFEYYADL 124 Query: 177 ASDLYAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANL-IGAPALMGNTVVW 233 A L A+Q PV T+ R G V ++P+N+ + A + G + Sbjct: 125 AEKLDARQKAPVSLPMDTFKSHVLREPIGVVGLITPWNYPMLMATWKVAPALAAGCAAIL 184 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KPS+ A+L+ L + +E GLP GV+N + G + + D + FTGS+ Sbjct: 185 KPSELASLTCLELGEICKEVGLPPGVLNILTGLGPEAGAPLATHPDVDKVAFTGSSAT-- 242 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 S ++ + + E GGK+ +V ++ A I G F GQ CSA Sbjct: 243 ------GSKIMTAAAQLVKPVSLELGGKSPLVVFEDVDLDKAAEWAIFGCFWTNGQICSA 296 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 SRL L ES + EFL+ + +++ + + P+ G +GPV+ E ++K++K Sbjct: 297 TSRLILHESIATEFLNRIVKWIKNIKI------SDPLEEGCR---LGPVVSEGQYEKILK 347 Query: 414 VIEDAKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPD 471 + +AK + IL GG + +G+F+ PT+I + E FGP+L V + Sbjct: 348 FVSNAKSE-GATILTGGSRPEHLKKGFFIEPTIITDVTTNMQIWREEVFGPVLCVKTFST 406 Query: 472 TEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWF 531 E E D+ ++T Y L A+ + D + E + F AG ++N C+ +Q + Sbjct: 407 EE--EAIDLANDTV-YGLGAAVISNDLERCERVTK--AFKAGIVWVN--CSQPCFTQAPW 459 Query: 532 GGARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 GG + SG + G L ++S++ + E Sbjct: 460 GGVKRSGFGRELGEWG-LDNYLSVKQVTQYISE 491 >5KLK-A nrPDB Length = 520 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 130/480 (27%), Positives = 214/480 (44%), Gaps = 45/480 (9%) Query: 79 FPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA-KKDWYNLPFYDRSAIFLKAADLIST 137 F NP N +++++V +A K V AV AA++A K W L DR+A+ K AD I Sbjct: 55 FANINPVN-GKLISDVFEADAKQVNEAVVAAQNALKGPWGKLSVQDRAALIHKIADGIQA 113 Query: 138 KYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA----SDLYAQQPVESADGTW 193 ++ + +AA + G+ V+QA I FR + A +DL+ + G Sbjct: 114 RFE-EFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHTDLF-EMSTSDGSGAL 171 Query: 194 NKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEE 252 N +PL G + +SP++ + APAL GNTVV KPS+ + S LL V+ + Sbjct: 172 NYTVRKPL-GVIGVISPWDLPLLLFTWKVAPALACGNTVVAKPSEESPSSATLLAEVMHD 230 Query: 253 AGLPKGVINFIPGDPVQVTDQVLADK-DFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDY 311 AG+P GV N I G + L AL FTG + ++ + GV E + Sbjct: 231 AGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVADGVKEVSF--- 287 Query: 312 PRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDM 371 E GGKN +V A++ A+ +R +F GQ C + R+Y+ S +EF+S + Sbjct: 288 -----ELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGL 342 Query: 372 FGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGG- 430 ++++ +V ++ MGP+I DK++ A + + GG Sbjct: 343 --KVEAERLVVGYPDQDGVN-------MGPLISHGHRDKVLSYYRLAVDEGATVVTGGGV 393 Query: 431 ---QYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQY 487 ++ QG +V PT+ ++ E FGP+ + + D + E+ + + N S Y Sbjct: 394 PKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDED--EVINRV-NDSNY 450 Query: 488 ALTGAIFAKDRKAIEYADEKLKFS---AGNFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544 L AI+ + ++ +Y+ D T FGG ++SG + G Sbjct: 451 GLACAIWTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTP-------FGGVKLSGLGREGG 503 >4DNG-A nrPDB Length = 485 Score = 139 bits (349), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 131/469 (27%), Positives = 219/469 (46%), Gaps = 36/469 (7%) Query: 88 QQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAAT 147 Q V+ + AT K + +A A+ A+K+W DR A+ KA + + R D++ Sbjct: 32 QSVITTASLATGKQLEDAFDIAQKAQKEWAKSTTEDRKAVLQKARGYLH-ENRDDIIMMI 90 Query: 148 MLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVES-ADGTWNKAEYRPLEGFVY 206 G + ++ I+ ++ + Y +L + V S +G NK PL G + Sbjct: 91 ARETGGTIIKSTIELEQTIA-ILDEAMTYTGELGGVKEVPSDIEGKTNKIYRLPL-GVIS 148 Query: 207 AVSPFNFTAIAANLIGAPAL-MGNTVVWKPS-QTAALSNYLLMTVLEEAGLPKGVINFIP 264 ++SPFNF + APA+ +GN+VV KP QTA ++ E AGLP GV+N + Sbjct: 149 SISPFNFPMNLSMRSIAPAIALGNSVVHKPDIQTAISGGTIIAKAFEHAGLPAGVLNVML 208 Query: 265 GDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFH 324 D ++ D +L + + FTGST V + + G + G R + R+ E GG N Sbjct: 209 TDVKEIGDGMLTNPIPRLISFTGSTAVGRHI------GEIAG--RAFKRMALELGGNNPF 260 Query: 325 LVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMN 384 V A++ AV + I G F QGQ C +R+ + + +EF+ ++ +P Sbjct: 261 AVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHQDVYDEFVEKFTARVKQ---LPYG 317 Query: 385 TSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTV 444 P + +GP+I+E+ +K +++IE AK D +E+ G K G + P V Sbjct: 318 DQTDP------KTVVGPLINERQIEKALEIIEQAKTDG-IELAVEG---KRVGNVLTPYV 367 Query: 445 IKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKD-RKAIEY 503 + TE F PI T+ + + E D+ ++T +Y L+ A+F D K ++ Sbjct: 368 FVGADNNSKIAQTELFAPIATIIKAGSDQ--EAIDMANDT-EYGLSSAVFTSDLEKGEKF 424 Query: 504 ADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRF 552 A L+ +G ++ND+ FGG + SG + G P ++ F Sbjct: 425 A---LQIDSGMTHVNDQSVND-SPNIAFGGNKASGV-GRFGNPWVVEEF 468 >1BPW-A nrPDB Length = 503 Score = 137 bits (346), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 126/483 (26%), Positives = 213/483 (44%), Gaps = 44/483 (9%) Query: 66 NGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRS 125 G RI + P PA + VL + ++V AV++A+ A W + +RS Sbjct: 25 GGRRIKSKDGATTEPVFEPATGR-VLCQMVPCGAEEVDQAVQSAQAAYLKWSKMAGIERS 83 Query: 126 AIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQP 185 + L+AA +I + R ++ ++ GK + +AE D I YY A L Q Sbjct: 84 RVMLEAARIIRER-RDNIAKLEVINNGKTITEAEYD-IDAAWQCIEYYAGLAPTLSGQH- 140 Query: 186 VESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNY 244 ++ G + PL G + +N+ + A APAL GN VV+KPS ++ Sbjct: 141 IQLPGGAFAYTRREPL-GVCAGILAWNYPFMIAAWKCAPALACGNAVVFKPSPMTPVTGV 199 Query: 245 LLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVV 304 +L + EAG+P G++N + G + + + + FTGS K V+ Sbjct: 200 ILAEIFHEAGVPVGLVNVVQGG-AETGSLLCHHPNVAKVSFTGSVPTGKK--------VM 250 Query: 305 EGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKS 364 E + + E GGK+ L+ + +AV + F QGQ C+ +R+++ Sbjct: 251 EMSAKTVKHVTLELGGKSPLLIFKDCELENAVRGALMANFLTQGQVCTNGTRVFVQREIM 310 Query: 365 EEFLSDMFGILQSQNVV---PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKD 421 +FL ++ + +++ +V P+ T MG +I + DK++ + AKK+ Sbjct: 311 PQFLEEV--VKRTKAIVVGDPLLTETR----------MGGLISKPQLDKVLGFVAQAKKE 358 Query: 422 PELEILYGGQ------YDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 +L GG+ G+F+ P V+ R D + E FGP+++V + DTE Sbjct: 359 GA-RVLCGGEPLTPSDPKLKNGYFMSPCVLDNCRDDMTCVKEEIFGPVMSVLPF-DTE-E 415 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 E+ +NT+ + L +F +D L+ AG YIN V + FGG + Sbjct: 416 EVLQRANNTT-FGLASGVFTRDISRAHRVAANLE--AGTCYINTYSISPV--EVPFGGYK 470 Query: 536 MSG 538 MSG Sbjct: 471 MSG 473 >4CAZ-A nrPDB Length = 490 Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 132/510 (25%), Positives = 225/510 (44%), Gaps = 43/510 (8%) Query: 67 GERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSA 126 G R + + A F NPAN + VLA V +A+ +DV AV++A + +K W + RS Sbjct: 12 GGRYVEASSGATFETINPANGE-VLAKVQRASREDVERAVQSAVEGQKVWAAMTAMQRSR 70 Query: 127 IFLKAADLISTKYRYDMLAA-TMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQ- 184 I +A D++ + R D LAA L GK + + I +D YY + +Q Sbjct: 71 ILRRAVDIL--RERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIEGEQI 128 Query: 185 PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSN 243 P+ + + E PL G V + +N+ A APAL GN +++KPS+ L+ Sbjct: 129 PLRETSFVYTRRE--PL-GVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPLTA 185 Query: 244 YLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGV 303 L + EAG+P GV N + G +V + + FTG T+ K + S Sbjct: 186 LKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASSSS 245 Query: 304 VEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESK 363 ++ + E GGK+ ++ P A++ A + F GQ C+ +R+++ S+ Sbjct: 246 LK-------EVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQ 298 Query: 364 SEEFLSDMFGILQSQNVV-PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDP 422 F + + +Q + P + + + GP++ + ++ IE K Sbjct: 299 QARFEAKVLERVQRIRLGDPQDENTN----------FGPLVSFPHMESVLGYIESGKAQ- 347 Query: 423 ELEILYGGQYDK----SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 + +L GG+ +G +V PTV R D + E FGP++++ Y D E I Sbjct: 348 KARLLCGGERVTDGAFGKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVY-DDEDEAIR 406 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 N ++Y L + +D A +L+ AG +IN G ++ GG + SG Sbjct: 407 RA--NDTEYGLAAGVVTQDLARAHRAIHRLE--AGICWIN--TWGESPAEMPVGGYKQSG 460 Query: 539 TDDKAGGPNILSRFVSIRNTKENFYELTDF 568 + G L+ + I++ + EL D+ Sbjct: 461 V-GRENGLTTLAHYTRIKSVQ---VELGDY 486 >2D4E-A nrPDB Length = 515 Score = 134 bits (337), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 132/492 (26%), Positives = 221/492 (44%), Gaps = 48/492 (9%) Query: 79 FPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTK 138 FP +PA ++ VL + E++V A KAA +A + W +R L+ A+LI Sbjct: 44 FPSLDPATNE-VLGVAARGGEREVDRAAKAAHEAFQRWSRTKAKERKRYLLRIAELIEKH 102 Query: 139 YRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQ--PVESADGTWNKA 196 D LA V + + ++ F +Y +YA + PV D W Sbjct: 103 A--DELAVMECLDAGQVLRIVRAQVARAAENFAFYAEYAEHAMEDRTFPV---DRDWLYY 157 Query: 197 EYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGL 255 R G V ++P+N + + APAL GNTVV KP++ + + L +L+EA L Sbjct: 158 TVRVPAGPVGIITPWNAPLMLSTWRIAPALAFGNTVVLKPAEWSPFTATKLAEILKEADL 217 Query: 256 PKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRII 315 P GV N + G + ++A L TG T GKI V+ R+ Sbjct: 218 PPGVFNLVQGFGEEAGAALVAHPLVPLLTLTGETET-----GKI---VMRNAADHLKRLS 269 Query: 316 GETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGIL 375 E GGK+ LV A++ A+ + + F F G++C+A+SRL + E E+F+ ++ Sbjct: 270 PELGGKSPALVFADADLERALDAVVFQIFSFNGERCTASSRLLVEEKIFEDFVGK---VV 326 Query: 376 QSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQY--- 432 + + + P + +GP+IH + +++ +E K++ +L GG+ Sbjct: 327 ERARAIRVGHPLDPETE------VGPLIHPEHLQRVLGYVEAGKREGA-RLLVGGERAKT 379 Query: 433 -----DKSQGWFVGPTVIKAKRPDHPYMST-EFFGPILTVYEYPDTEFNEICDIIDNTSQ 486 D S+G ++ PTV + +H ++ E FGP+L + D E E ++T + Sbjct: 380 SFRGEDLSRGNYLLPTVFVGE--NHMKIAQEEIFGPVLVAIPFKDEE--EALRKANDT-K 434 Query: 487 YALTGAIFAKDRKAIEYADE-KLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGG 545 Y L +F +D +E A L+ AG Y+N + + FGG + SG D + GG Sbjct: 435 YGLAAYVFTRD---LERAHRLALELEAGMVYLNSHNVRHLPTP--FGGVKGSG-DRREGG 488 Query: 546 PNILSRFVSIRN 557 L + ++ Sbjct: 489 TYALDFYTDLKT 500 >4I8P-A nrPDB Length = 520 Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 128/456 (28%), Positives = 204/456 (44%), Gaps = 33/456 (7%) Query: 110 KDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDF 169 ++ +DW P R A +L+A + + ++ L GK +A D + +++ Sbjct: 77 RNRGRDWARAPGAVR-AKYLRAIAAKVIERKPELAKLEALDCGKPYDEAAWD-MDDVAGC 134 Query: 170 FRYYVKYASDLYAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM 227 F Y+ A L +Q PV T+ R G V ++P+N+ + A APAL Sbjct: 135 FEYFADQAEALDKRQNSPVSLPMETFKCHLRREPIGVVGLITPWNYPLLMATWKIAPALA 194 Query: 228 -GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFT 286 G T V KPS+ A+++ L + +E GLP GV+N + G + A D + FT Sbjct: 195 AGCTAVLKPSELASVTCLELADICKEVGLPSGVLNIVTGLGPDAGAPLSAHPDVDKVAFT 254 Query: 287 GSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF 346 GS K + V + E GGK+ +V +I AV T+ G F Sbjct: 255 GSFETGKKIMASAAPMVKP--------VTLELGGKSPIVVFDDVDIDKAVEWTLFGCFWT 306 Query: 347 QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQ 406 GQ CSA SRL + +++F M ++ V + P+ G +GPV+ E Sbjct: 307 NGQICSATSRLLIHTKIAKKFNERMVAWAKNIKV------SDPLEEGCR---LGPVVSEG 357 Query: 407 SFDKLVKVIEDAKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPIL 464 ++K+ K I +AK IL GG +G+F+ PT+I E FGP+L Sbjct: 358 QYEKIKKFISNAKSQ-GATILTGGVRPAHLEKGFFIEPTIITDITTSMEIWREEVFGPVL 416 Query: 465 TVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGA 524 V E+ TE I + N +QY L GA+ + DR+ + E++ AG ++N C+ Sbjct: 417 CVKEF-STEDEAI--ELANDTQYGLAGAVISGDRERCQRLSEEI--DAGCIWVN--CSQP 469 Query: 525 VVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKE 560 Q +GG + SG + G I ++S++ E Sbjct: 470 CFCQAPWGGNKRSGFGRELGEGGI-DNYLSVKQVTE 504 >4GO4-A nrPDB Length = 495 Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 132/444 (29%), Positives = 201/444 (45%), Gaps = 42/444 (9%) Query: 110 KDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDF 169 K A W L +R + LK AD I + ++ L G + + + + Sbjct: 50 KRAFPAWSALGAAERGRLLLKLADRIE-ECSEELAQLESLNTGHPIRDSRGLDVPRTAAC 108 Query: 170 FRYYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM- 227 FRY+ A + PV++ G N + +P+ G V + P+NF + + PAL Sbjct: 109 FRYFGGMADKIEGSVIPVDA--GFLNYVQRKPI-GVVAQIVPWNFPLMFTSWKMGPALAA 165 Query: 228 GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK-DFGALHFT 286 GNT+V KPS+ LS ++ ++ E G PKGV+N +PG Q LA+ D G + FT Sbjct: 166 GNTIVIKPSEITPLSTLRIVELMTEVGFPKGVVNVVPGYG-HTAGQALAEHLDVGKIAFT 224 Query: 287 GSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF 346 GST + +VE + RI E GGK ++V ANI AV F Sbjct: 225 GSTATGRR--------IVEASKSNLKRIQLELGGKGANIVFEDANIEAAVNGAAWAIFHN 276 Query: 347 QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV-PMNTSASPISGGNLRGFMGPVIHE 405 QGQ C A SRL L + +++FL + +S + PM+ MGP+ Sbjct: 277 QGQACIAGSRLILHKDIADQFLERFIALAKSIRLGDPMDPETE----------MGPLTSA 326 Query: 406 QSFDKLVKVIEDAKKDPELEILYGGQY--DK--SQGWFVGPTVIKAKRPDHPYMSTEFFG 461 D+++ I+ A + ++L GG+ DK + G++V PTV++AK P E FG Sbjct: 327 LRRDRVLSYIDIAIEQGG-KVLAGGKAPDDKALANGFYVEPTVVEAK-PQDRVCQEEVFG 384 Query: 462 PILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDK 520 P +TV + E E I +NT +Y L ++ ++ +A + A AG +IN Sbjct: 385 PFVTVVRFSSDE--EALAIANNT-EYGLGSGLWTQNLARAHKMAH---AIHAGMCWIN-- 436 Query: 521 CTGAVVSQQWFGGARMSGTDDKAG 544 C V FGG SG + G Sbjct: 437 CYKRVSPGSPFGGVGQSGYGREMG 460 >3PRL-A nrPDB Length = 505 Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 129/483 (26%), Positives = 227/483 (46%), Gaps = 44/483 (9%) Query: 91 LANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLG 150 L ++ ++++V +A++ AKDA+K W P ++R + ADL+ + R +++ ++ Sbjct: 40 LGSIPALSQEEVNDAIQGAKDAQKIWKIRPIHERVDLLYAWADLL--EERKEIIGELIMH 97 Query: 151 QGKNVYQAEIDCITELSDFFRYYVKYASDLYAQ--QPVESADGTWNK---AEYRPLEGFV 205 + ++ I ++ +D R+ A L + + + G+ K E PL G V Sbjct: 98 EVAKPKKSAIGEVSRTADIIRHTADEALRLNGETLKGDQFKGGSSKKIALVEREPL-GVV 156 Query: 206 YAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIP 264 A+SPFN+ A APAL+ GNTVV+KP+ +LS ++ L +AG P+G+I + Sbjct: 157 LAISPFNYPVNLAAAKIAPALVTGNTVVFKPATQGSLSGIKMVEALADAGAPEGIIQVVT 216 Query: 265 GDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFH 324 G + D ++ + FTG T + + K + P ++ E GGK+ Sbjct: 217 GRGSVIGDHLVEHPGIDMITFTGGTTTGER---------ISEKAKMIPVVL-ELGGKDPA 266 Query: 325 LVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMN 384 +V A++ + G F + GQ+C+A R+++ +S +++ ++++ + +V Sbjct: 267 IVLDDADLKLTASQIVSGAFSYSGQRCTAIKRVFVQDSVADQLVANI------KELVEQL 320 Query: 385 TSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTV 444 T SP ++ PVI E+S + +I+DA ++ +L G +K QG + PT+ Sbjct: 321 TVGSPEDDADIT----PVIDEKSAAFIQGLIDDALENGA-TLLSG---NKRQGNLLSPTL 372 Query: 445 IKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDR-KAIEY 503 + P E FGP+L + D NE + N S Y L +IF KD +AI Sbjct: 373 LDDVTPAMRVAWEEPFGPVLPIIRVKDA--NEAIS-LSNQSDYGLQASIFTKDTDRAINI 429 Query: 504 ADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILS---RFVSIRNTKE 560 G +IN K T F G + SG + P++LS V++ N E Sbjct: 430 GKH---LEVGTVHINAK-TERGPDHFPFLGVKKSGLGVQGIKPSLLSMTRERVTVLNLAE 485 Query: 561 NFY 563 N Y Sbjct: 486 NLY 488 >4MPY-A nrPDB Length = 520 Score = 132 bits (332), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 141/502 (28%), Positives = 221/502 (44%), Gaps = 47/502 (9%) Query: 65 INGERI--YDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA--KKDWYNLP 120 I+GE + + N R + NP N Q+V+ V++ T++D A+ AA+ A +W Sbjct: 37 IDGEWVESANKNTRDII---NPYN-QEVIFTVSEGTKEDAERAILAARRAFESGEWSQET 92 Query: 121 FYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 R AD I ++R + L GK + ++ D + ++ + F Y+ A Sbjct: 93 AETRGKKVRAIADKIK-EHREALARLETLDTGKTLEESYAD-MDDIHNVFMYFAGLADKD 150 Query: 181 YAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTA 239 + T +K P+ G V ++P+N+ + A+ APAL G ++V KPS+ Sbjct: 151 GGEMIDSPIPDTESKIVKEPV-GVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEIT 209 Query: 240 ALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKI 299 L+ + ++EE G PKG IN I G +V D + K+ + FTG K + Sbjct: 210 PLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNA 269 Query: 300 QSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYL 359 + V I E GGKN +++ A+ AV + G + GQ CSA SR+ + Sbjct: 270 ANNVT--------NIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILV 321 Query: 360 PES---KSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 S K E+ L D ++ N +T MGPVI + +K+ ++ Sbjct: 322 QNSIKDKFEQALIDRVKKIKLGNGFDADTE------------MGPVISTEHRNKIESYMD 369 Query: 417 DAKKDPELEILYGGQY----DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 AK + I GG+ D G F PTVI + E FGP++TV + +T Sbjct: 370 VAKAEGAT-IAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGF-ET 427 Query: 473 EFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFG 532 E I + N S Y L GA+F+KD + KLK G +IND +Q +G Sbjct: 428 EQEAIQ--LANDSIYGLAGAVFSKDIGKAQRVANKLKL--GTVWIND--FHPYFAQAPWG 481 Query: 533 GARMSGTDDKAGGPNILSRFVS 554 G + SG + G + VS Sbjct: 482 GYKQSGIGRELGKEGLEEYLVS 503 >4QYJ-A nrPDB Length = 516 Score = 129 bits (324), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 137/513 (26%), Positives = 226/513 (44%), Gaps = 41/513 (7%) Query: 47 LRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAV 106 + +SL L ++I G+ + + + L NPA +L V +DV AV Sbjct: 21 MNSSLSAIDGLRLPHQMLIGGQWVSAQSGKTLN-VYNPAT-GDILTEVPDGDVEDVNAAV 78 Query: 107 K-AAKDAKKD-WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCIT 164 + AA + D W +P R I L+ ADL+ + ++ L GK + +++ + Sbjct: 79 ESAAATLRSDTWRRMPPSARERILLRLADLLEV-HGDELARLETLNNGKLLIYSKLMEVG 137 Query: 165 ELSDFFRYYVKYASDLYAQQ-----PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAAN 219 + + RY +A+ L P+ + + P+ G V A+ P+NF + A Sbjct: 138 ASAQWLRYMAGWATKLTGSTLDLSLPLPPEVRSRASTQRVPV-GVVAAIIPWNFPLLMAV 196 Query: 220 LIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK 278 APAL GNTVV KP++ L+ L + EAGLP G +N + G D ++ Sbjct: 197 WKIAPALACGNTVVLKPAEETPLTALRLAELAMEAGLPAGALNVVTGRGETAGDALVRHP 256 Query: 279 DFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLS 338 + FTGST V G+I + R + E GGK+ +V + A Sbjct: 257 KVAKVAFTGSTEV-----GRI---IGSACGRSLKAVSLELGGKSPVIVLADCDPQEAAEG 308 Query: 339 TIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGF 398 F GQ C+A SRLY+ ES E+ + Q + + S SG Sbjct: 309 AAAAIFFNHGQVCTAGSRLYVHESIYEDVI---------QRLAVIGESIVVGSGLEQGVH 359 Query: 399 MGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAK-RPDHPYMST 457 MGP++ ++ + +++ I + +D I G + +QG+FV PT+ + + D +S Sbjct: 360 MGPMVSKKHHENVLRHIRNGIEDGADLICGGTEAPCAQGFFVKPTIFANREKKDIRLLSQ 419 Query: 458 EFFGPILTVYEYPDTEFNEICDIID--NTSQYALTGAIFAKDRKAIEYADEKLKFSAGNF 515 E FGP+L T F++I ++++ N S Y L +I+ D A +++L+ AG Sbjct: 420 EVFGPVLVA-----TPFSDIAEVVNEANRSVYGLGASIWTNDLSAALRINDELE--AGTV 472 Query: 516 YINDKCTGAVVSQQWFGGARMSGTDDKAGGPNI 548 ++N V FGG + SG + G I Sbjct: 473 WVNTH--NMVDPNLPFGGFKDSGVGREHGAAAI 503 >3R64-A nrPDB Length = 508 Score = 127 bits (320), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 140/507 (27%), Positives = 236/507 (46%), Gaps = 38/507 (7%) Query: 64 VINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYD 123 +I G+ + N++R + NP + V+A QA+ DV A +AAK A+ +W P + Sbjct: 16 LIGGQWVEGNSDR-ISTNINPYD-DSVIAESKQASIADVDAAYEAAKKAQAEWAATPAAE 73 Query: 124 RSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQ 183 RSAI +AA+L+ ++R +++ + G +A ++ IT + + + ++ + Sbjct: 74 RSAIIYRAAELLE-EHREEIVEWLIKESGSTRSKANLE-ITLAGNITKESASFPGRVHGR 131 Query: 184 QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKP-SQTAAL 241 + G N+ YR +G V +SP+NF + APAL +GN VV KP S T Sbjct: 132 ISPSNTPGKENRV-YRVAKGVVGVISPWNFPLNLSIRSVAPALAVGNAVVIKPASDTPVT 190 Query: 242 SNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQS 301 + + EEAG+P GVI+ + G ++ D + + FTGST V + + + Sbjct: 191 GGVIPARIFEEAGVPAGVISTVAGAGSEIGDHFVTHAVPKLISFTGSTPVGRRVGELAIN 250 Query: 302 GVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPE 361 G G + + E GG +V A+I A + G F QGQ C + +R+ + Sbjct: 251 G---GPMK---TVALELGGNAPFVVLADADIDAAAQAAAVGAFLHQGQICMSINRVIVDA 304 Query: 362 SKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKD 421 + +EFL +++ +P + P + G L +GPVI++ L + IE AKK+ Sbjct: 305 AVHDEFLEKF---VEAVKNIP---TGDPSAEGTL---VGPVINDSQLSGLKEKIELAKKE 355 Query: 422 PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII 481 + G +G V P V D E FGP+++V + D + Sbjct: 356 GATVQVEG----PIEGRLVHPHVFSDVTSDMEIAREEIFGPLISVLKADDEAH---AAEL 408 Query: 482 DNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTD 540 N S + L+ A+++KD +A ++A L+ +G +IND T FGG++ SG Sbjct: 409 ANASDFGLSAAVWSKDIDRAAQFA---LQIDSGMVHIND-LTVNDEPHVMFGGSKNSGLG 464 Query: 541 DKAGGPNI----LSRFVSIRNTKENFY 563 G I R++ I+ + EN Y Sbjct: 465 RFNGDWAIEEFTTDRWIGIKRSAENLY 491 >4ZZ7-A nrPDB Length = 501 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 134/505 (26%), Positives = 223/505 (44%), Gaps = 45/505 (8%) Query: 64 VINGERIYDNNE-RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFY 122 +ING+ + +N + +F NPA ++ + A+ K V A+ AA+ A W N P Sbjct: 10 LINGQLVTENTRSQNVF---NPAT-GEIGKQLDLASTKTVEQAISAAQHAFPTWRNTPPL 65 Query: 123 DRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD--- 179 R+ + + +L+ ++ ++ GK + D + EL V+YA Sbjct: 66 KRARVMFRFKELLE-QHADEICRLIGEEHGKIAH----DAMGELQRGIEN-VEYACGAPE 119 Query: 180 -LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 L + G + +E++P+ G V ++PFNF + + A++ GN V KPS+ Sbjct: 120 LLKGEHSRNVGPGIDSWSEFQPM-GVVAGITPFNFPVMVPLWMFPMAIVCGNCFVLKPSE 178 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 S + +L+EAGLP GV+N + GD + D +L D A+ F GST + + +Y Sbjct: 179 RDPSSTLYIAQLLQEAGLPDGVMNVVNGDK-EAVDALLHDDRVKAVSFVGSTPIAEYIY- 236 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAAS-R 356 ++ GK R G KN +V P A++ +AV + F G++C A S Sbjct: 237 --RTASANGK-----RCQALGGAKNHAIVMPDADMDNAVNQLLGAAFGSSGERCMALSVA 289 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 + + ++ + +S M +Q V P S + GPVI Q +K++ I Sbjct: 290 VAVGDAAGDALVSKMTQAMQKLKVGPSTDSGNDF---------GPVITRQHQEKVIGYIN 340 Query: 417 DAKKDPELEILYGGQ---YDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 A++ ++ G Q + G+FVG T+I P+ E FGP+L V Sbjct: 341 SAEQQGATIVVDGRQPKVPNHENGFFVGGTLIDHVTPEMTSYQEEIFGPVLQVVRV--AT 398 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 + D+ID +Y IF +D +A Y + ++ G IN V + G Sbjct: 399 MQDAMDLID-AHEYGNGTCIFTRDGEAARYFSDNIQV--GMVGINIPLPVPVAYHSFGGW 455 Query: 534 ARMSGTDDKAGGPNILSRFVSIRNT 558 R D A GP+ + RF + R T Sbjct: 456 KRSLFGDLHAYGPDAV-RFYTKRKT 479 >6QAO-A nrPDB Length = 508 Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 124/477 (25%), Positives = 223/477 (46%), Gaps = 50/477 (10%) Query: 73 NNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAA 132 E+A P T +V+A T + EK+V AV+ AK A K W +R I L+AA Sbjct: 41 GTEKAFEPATG-----RVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERCRILLEAA 95 Query: 133 DLISTKYRYDMLAAT-MLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADG 191 +I + R D +A + GK++++A +D I YY A+ + A + ++ G Sbjct: 96 RII--REREDEIATMECINNGKSIFEARLD-IDISWQCLEYYAGLAASM-AGEHIQLPGG 151 Query: 192 TWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVL 250 ++ PL G + +N+ A+ APAL GN +V+KPS +S LL + Sbjct: 152 SFGYTRREPL-GVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIY 210 Query: 251 EEAGLPKGVINFIPGDPVQVTDQVLADK-DFGALHFTGSTNVFKSLYGKIQSG--VVEGK 307 EAG+P G+ N + G T Q L D + FTGS + +G ++E Sbjct: 211 SEAGVPPGLFNVVQGG--AATGQFLCQHPDVAKVSFTGS----------VPTGMKIMEMS 258 Query: 308 YRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEF 367 + + E GGK+ ++ ++++AV + F QGQ C +R+++ + ++F Sbjct: 259 AKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKF 318 Query: 368 LSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEIL 427 ++ + Q+Q + P+ MGP+I+ ++++ ++ AK+ ++L Sbjct: 319 TEEV--VKQTQRI----KIGDPLLEDTR---MGPLINRPHLERVLGFVKVAKEQGA-KVL 368 Query: 428 YGGQY------DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII 481 GG G+++ P V+ R D + E FGP++++ + DTE E+ + Sbjct: 369 CGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSF-DTE-AEVLERA 426 Query: 482 DNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 ++T+ + L +F +D + +L+ AG +IN+ V + FGG + SG Sbjct: 427 NDTT-FGLAAGVFTRDIQRAHRVVAELQ--AGTCFINNYNVSPV--ELPFGGYKKSG 478 >1T90-A nrPDB Length = 486 Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 121/460 (26%), Positives = 202/460 (43%), Gaps = 39/460 (8%) Query: 65 INGERI---YDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPF 121 INGE + D E + P T ++VL V +T++D+ A + A +A K W + Sbjct: 10 INGEWVESKTDQYEDVVNPAT-----KEVLCQVPISTKEDIDYAAQTAAEAFKTWSKVAV 64 Query: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQA--EIDCITELSDFFRYYVKYASD 179 R+ I L+S +++ ++ + GKN +A E+ E +F A Sbjct: 65 PRRARILFNFQQLLS-QHKEELAHLITIENGKNTKEALGEVGRGIENVEF----AAGAPS 119 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQT 238 L + S A YR G V ++PFNF + + A+ +GNT + KPS+ Sbjct: 120 LMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPSER 179 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 L L+ + E+AGLPKGV N + G V + +L + A+ F GS V + +Y K Sbjct: 180 TPLLTEKLVELFEKAGLPKGVFNVVYGAH-DVVNGILEHPEIKAISFVGSKPVGEYVYKK 238 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 + R+ TG KN +V AN+ V + + F G++C A + + Sbjct: 239 --------GSENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVT 290 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + E ++EF++ + + V + +G + F+GPVI E + + + IE Sbjct: 291 VEEGIADEFMAKL-----QEKVADIKIG----NGLDDGVFLGPVIREDNKKRTLSYIEKG 341 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 ++ + G + G+FVGPT+ + E F P+L+V + E Sbjct: 342 LEEGARLVCDGRENVSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKN--LKEAI 399 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYIN 518 +I N S++A +F + AI Y E + AG IN Sbjct: 400 EIA-NKSEFANGACLFTSNSNAIRYFRENI--DAGMLGIN 436 >2HG2-A nrPDB Length = 479 Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 118/493 (23%), Positives = 229/493 (46%), Gaps = 36/493 (7%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 S ++ P+ I+G+ + + A NPA + V++ + +D A+ AA+ A+ + Sbjct: 2 SVPVQHPMYIDGQFVTWRGD-AWIDVVNPAT-EAVISRIPDGQAEDARKAIDAAERAQPE 59 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQ-AEIDCITELSDFFRYYV 174 W LP +R++ K + I + R ++A ++ +G + Q AE++ + +D+ Y Sbjct: 60 WEALPAIERASWLRKISAGI--RERASEISALIVEEGGKIQQLAEVE-VAFTADYIDYMA 116 Query: 175 KYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVW 233 ++A Y + ++S N ++ G + P+NF APAL+ GNT+V Sbjct: 117 EWARR-YEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVI 175 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KPS+ + +++E GLP+GV N + G V ++ + + TGS + + Sbjct: 176 KPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGE 235 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 + ++ ++ E GGK +V A++ AV + + GQ C+ Sbjct: 236 KIMAT--------AAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNC 287 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 A R+Y+ + ++F++ + +Q+ +P ++ MGP+I+ + +++ + Sbjct: 288 AERVYVQKGIYDQFVNRLGEAMQAVQF------GNPAERNDIA--MGPLINAAALERVEQ 339 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 + A ++ + +GG+ + +G++ PT++ R + M E FGP+L P Sbjct: 340 KVARAVEEGA-RVAFGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVL-----PVVA 393 Query: 474 FNEICDIID--NTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWF 531 F+ + D I N S Y LT +I+ ++ A + LKF G YIN + A+ Q + Sbjct: 394 FDTLEDAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKF--GETYINRENFEAM--QGFH 449 Query: 532 GGARMSGTDDKAG 544 G R SG G Sbjct: 450 AGWRKSGIGGADG 462 >3I44-A nrPDB Length = 497 Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 115/461 (24%), Positives = 201/461 (43%), Gaps = 34/461 (7%) Query: 88 QQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAAT 147 ++ A ++ + +D A+ AAK A + W ++R K + I K DM Sbjct: 51 EEACAVISLGSTRDADKAINAAKKAFQTWKTTSPHERLGFVEKILE-IYEKRSSDMAKTI 109 Query: 148 MLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYA 207 + G + A S R ++K + Q+ + +G + G V Sbjct: 110 SMEMGAPIDMALNAQTATGSSHIRNFIKAYKEFSFQEAL--IEGNEQAILHYDAIGVVGL 167 Query: 208 VSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGD 266 ++P+N+ L PAL+ G T+V KPS+ A LS L +L+EA LP GV N I GD Sbjct: 168 ITPWNWPMNQVTLKVIPALLAGCTMVLKPSEIAPLSAMLFAEILDEAALPSGVFNLINGD 227 Query: 267 PVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLV 326 V + A D + FTGST K + + R+ E GGK +++ Sbjct: 228 GANVGSYLSAHPDLEMISFTGSTRAGKD--------ISKNASNTLKRVCLELGGKGANII 279 Query: 327 HPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTS 386 A+I A+ +R F GQ C+A +R+ + ++ ++ + I + V P + + Sbjct: 280 FADADID-ALQRGVRHCFYNSGQSCNAPTRMLVEQAIYDKAIKTAKDIAEKTQVGPGHQT 338 Query: 387 ASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQ---YDKSQGWFVGPT 443 + I GPV+ ++ +DK+ +I+ D ++ GG +G++V PT Sbjct: 339 GNHI---------GPVVSKEQYDKIQDLIQSG-IDEGATLVTGGTGLPMGMERGYYVRPT 388 Query: 444 VIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEY 503 V +P E FGP+L++ + +TE + + N ++Y LT I ++DR Sbjct: 389 VFADVKPHMRIFREEIFGPVLSLLPF-NTEDEAVT--LANDTEYGLTNYIQSQDRSKCRR 445 Query: 504 ADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544 +++ +G +N + +FGG + SG + G Sbjct: 446 IAAQVR--SGMVEVNGH---ELPGGSYFGGVKFSGRAREGG 481 >4PXL-B nrPDB Length = 517 Score = 126 bits (316), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 135/520 (25%), Positives = 227/520 (43%), Gaps = 45/520 (8%) Query: 57 SSLEVP--------LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKA 108 S EVP L I+G + D F +P +V+A++ + + DV AVKA Sbjct: 25 GSFEVPKVEVRFTKLFIDG-KFVDAVSGKTFETRDP-RTGEVIASIAEGDKADVDLAVKA 82 Query: 109 AKDAKKD--WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITEL 166 A++A + W + Y+R I + ADLI ++ ++ A + GK + I Sbjct: 83 AREAFDNGPWPRMTGYERGRILHRFADLID-EHVEELAALDTVDAGKLFAVGKARDIPGA 141 Query: 167 SDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL 226 + RYY A ++ ++ A P+ G V + P+N+ PAL Sbjct: 142 AHLLRYYAGAADKVHGAT-LKMAQRMHGYTLKEPV-GVVGHIVPWNYPTTMFFFKVGPAL 199 Query: 227 M-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHF 285 G VV KP++ LS + EAG+P GV+N +PG V A D + F Sbjct: 200 AAGCAVVVKPAEQTPLSALFYAHLAREAGVPAGVLNVVPGFGPTAGAAVAAHMDVDKVSF 259 Query: 286 TGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFE 345 TGST V + + E + + E GGK+ +V A++ AV T+ Sbjct: 260 TGSTEVGRL----VMRAAAESNLKP---VSLELGGKSPVIVFDDADLDMAVNLVNFATYT 312 Query: 346 FQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV--PMNTSASPISGGNLRGFMGPVI 403 +G+ C A +R+Y+ E +EF+ L S++VV P N S S GP + Sbjct: 313 NKGEICVAGTRIYVQEGIYDEFVKKA-AELASKSVVGDPFNPSVS----------QGPQV 361 Query: 404 HEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI 463 + ++K+++ I+ K++ ++ GG+ +G+++ PT+ + D E FGP+ Sbjct: 362 DKDQYEKVLRYIDIGKRE-GATLVTGGKPCGDKGYYIEPTIFTDVKDDMTIAQDEIFGPV 420 Query: 464 LTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTG 523 + + ++ E E+ +NT +Y L I K+ ++ AG +IN C Sbjct: 421 MALMKFKTVE--EVIQKANNT-RYGLAAGIVTKNIDVANTVSRSIR--AGAIWIN--CYF 473 Query: 524 AVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFY 563 A FGG +MSG K G + L +++ + Y Sbjct: 474 AFDPDAPFGGYKMSGF-GKDMGMDALDKYLQTKTVVTPLY 512 >3RHD-A nrPDB Length = 486 Score = 125 bits (315), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 122/458 (26%), Positives = 213/458 (46%), Gaps = 47/458 (10%) Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM 148 +V+ + + ++ A+ A+ K+ NLP R I + A I K + ++ Sbjct: 23 EVIKKIPALSREEAKEAIDTAEKYKEVMKNLPITKRYNILMNIAKQIKEK-KEELAKILA 81 Query: 149 LGQGKNVYQAEIDCITELSDF--FRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVY 206 + GK + QA ++ + F +YVK D V +D P+ G V Sbjct: 82 IDAGKPIKQARVEVERSIGTFKLAAFYVKEHRD-----EVIPSDDRLIFTRREPV-GIVG 135 Query: 207 AVSPFNF-TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEA----GLPKGVIN 261 A++PFNF ++A+ I GN +V PS A L L ++E A +P GV N Sbjct: 136 AITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVCIELAKIIENALKKYNVPLGVYN 195 Query: 262 FIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGK 321 + G V D+++ ++ + FTGS+ V G + K + +I E GG Sbjct: 196 LLTGAGEVVGDEIVVNEKVNMISFTGSSKV----------GELITKKAGFKKIALELGGV 245 Query: 322 NFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV 381 N ++V A+++ AV + I+G+F + GQ C + + + ES +++F+ + NV Sbjct: 246 NPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADKFIEMFVNKAKVLNV- 304 Query: 382 PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVG 441 +P+ + + +GP+I + + + KV+E A D ++L GG+ DK+ + Sbjct: 305 -----GNPL---DEKTDVGPLISVEHAEWVEKVVEKA-IDEGGKLLLGGKRDKALFY--- 352 Query: 442 PTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKD-RKA 500 PT+++ R D+ TE F P++ + + E +I N+++Y L AIF D K+ Sbjct: 353 PTILEVDR-DNILCKTETFAPVIPIIRTNEEEMIDIA----NSTEYGLHSAIFTNDINKS 407 Query: 501 IEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 +++A E L+F G IND FGG + SG Sbjct: 408 LKFA-ENLEF--GGVVINDSSLFR-QDNMPFGGVKKSG 441 >3RHO-A nrPDB Length = 517 Score = 125 bits (314), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 128/492 (26%), Positives = 219/492 (44%), Gaps = 40/492 (8%) Query: 58 SLEVP--LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 +L++P L I GE + D + NP + V+ V+ A DV AV AAK+A ++ Sbjct: 32 TLQMPYQLFIGGEFV-DAEGSKTYNTINPTDGS-VICQVSLAQVSDVDKAVAAAKEAFEN 89 Query: 116 --WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELS-DFFRY 172 W + DR + + AD++ +++ ++ L G VY + +S FRY Sbjct: 90 GLWGKINARDRGRLLYRLADVME-QHQEELATIEALDAGA-VYTLALKTHVGMSIQTFRY 147 Query: 173 YVKYASDLY-AQQPVESADGTWNKA--EYRPLEGFVYAVSPFNFTAIAANLIGAPALM-G 228 + + + A P+ A N + P+ G V P+N+ + + A L G Sbjct: 148 FAGWCDKIQGATIPINQARPNRNLTLTKKEPV-GVCGIVIPWNYPLMMLSWKTAACLAAG 206 Query: 229 NTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGS 288 NTVV KP+Q L+ + +AG+PKGV+N +PG V ++ D + FTGS Sbjct: 207 NTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGS 266 Query: 289 TNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQG 348 T V K + + ++ + GGK+ ++ +++ AV + F +G Sbjct: 267 TEVGKHIMKSC-------ALSNVKKVSLQLGGKSPLIIFADCDLNKAVQMGMSSVFFNKG 319 Query: 349 QKCSAASRLYLPESKSEEFLSDMFGILQSQNVV-PMNTSASPISGGNLRGFMGPVIHEQS 407 + C AA RL++ ES +F+ + ++ + P+ + GP HE Sbjct: 320 ENCIAAGRLFVEESIHNQFVQKVVEEVEKMKIGNPLERDTN----------HGPQNHEAH 369 Query: 408 FDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMST-EFFGPILTV 466 KLV+ + K+ + G Q + G+F PTV DH Y++ E FGPI+ + Sbjct: 370 LRKLVEYCQRGVKEGATLVCGGNQVPRP-GFFFQPTVF-TDVEDHMYIAKEESFGPIMII 427 Query: 467 YEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVV 526 + D + + + N +++ L +F +D Y +KL+ AG +IN V Sbjct: 428 SRFADGDVDAVLSRA-NATEFGLASGVFTRDINKALYVSDKLQ--AGTVFINTYNKTDVA 484 Query: 527 SQQWFGGARMSG 538 + FGG + SG Sbjct: 485 AP--FGGFKQSG 494 >3R31-A nrPDB Length = 517 Score = 125 bits (314), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 128/484 (26%), Positives = 211/484 (43%), Gaps = 47/484 (9%) Query: 65 INGERIYDNNE---RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPF 121 I+G+ + DN ++FP T +++A + AT V A+ +AK A+K+W + Sbjct: 19 IDGDYVEDNTGTPFESIFPATG-----EMIAKLHAATPAIVERAIASAKRAQKEWAAMSP 73 Query: 122 YDRSAIFLKAADLISTKYRYDMLAA-TMLGQGKNVYQAEIDCITELSDFFRYYVKYA-SD 179 R I +AAD++ + R D L+ L GK + + + T +D F ++ A S Sbjct: 74 MARGRILKRAADIM--RERNDALSTLETLDTGKPIQETIVADPTSGADAFEFFGGIAPSA 131 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQT 238 L D + K R G + +N+ A APAL+ GN +V+KPS+ Sbjct: 132 LNGDYIPLGGDFAYTK---RVPLGVCVGIGAWNYPQQIACWKAAPALVAGNAMVFKPSEN 188 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 L + +L EAGLPKG+ N I G D+D G L SL G Sbjct: 189 TPLGALKIAEILIEAGLPKGLFNVIQG-----------DRDTGPLLVNHPDVAKVSLTGS 237 Query: 299 IQSG--VVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + +G V + E GGK+ +V A+I AV + G F GQ CS +R Sbjct: 238 VPTGRKVAAAAAGHLKHVTMELGGKSPMIVFDDADIESAVGGAMLGNFYSSGQVCSNGTR 297 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 +++ + FL ++ ++ + P+ + +GP++ + +K++ IE Sbjct: 298 VFVQKKAKARFLENLKRRTEAMIL------GDPL---DYATHLGPLVSKAQQEKVLSYIE 348 Query: 417 DAKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEF 474 K + I GG + +G +V PTV D E FGP++ V ++ D Sbjct: 349 KGKAEGATLITGGGIPNNVAGEGAYVQPTVFADVTDDMTIAREEIFGPVMCVLDFDDE-- 406 Query: 475 NEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGA 534 +E+ N +++ L G +F D + L+ AG +IN V + FGG+ Sbjct: 407 DEVL-ARANATEFGLAGGVFTADLARAHRVVDGLE--AGTLWINTYNLCPV--EIPFGGS 461 Query: 535 RMSG 538 + SG Sbjct: 462 KQSG 465 >4F3X-A nrPDB Length = 498 Score = 124 bits (312), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 126/473 (26%), Positives = 209/473 (44%), Gaps = 49/473 (10%) Query: 75 ERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADL 134 E L P+T + ++ +A+ + AV AA+ A W +RS LK AD Sbjct: 42 EHILNPRTGAG-----IIDLAEASHAQIDAAVDAAERAFVGWSQTTPAERSNALLKIADA 96 Query: 135 ISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWN 194 I K + A L GK + + D + + D +R++ +L+A E G + Sbjct: 97 IE-KEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTS 155 Query: 195 KAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMG-NTVVWKPSQTAALSNYLLMTVLEEA 253 P+ G V +++P+N+ + APA+ G NTVV+KPS+ L+ L ++ + Sbjct: 156 MIRRDPI-GIVGSIAPWNYPLMMMAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADI 214 Query: 254 GLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPR 313 LP+GV+N I G V + ++ G + TG K V+ + R Sbjct: 215 -LPEGVVNVITGRGETVGNALINHPKVGMVSITGDIATGKK--------VLAAAAKTVKR 265 Query: 314 IIGETGGKNFHLVHPSANISHAVLSTIRGTFEF--QGQKCSAASRLYLPESKSEEFLSDM 371 E GGK +V+ A++ AV++ IR TF + GQ C+AA R+Y E+ ++D+ Sbjct: 266 THLELGGKAPVIVYGDADL-EAVVNGIR-TFGYYNAGQDCTAACRIYAEAGIYEKLVADL 323 Query: 372 FGILQSQNVVPMNTSASPISGGNL----RGFMGPVIHEQSFDKLVKVIEDAKKDPELEIL 427 TSA NL +GP+I + D++ +E A +EI Sbjct: 324 -------------TSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEIT 370 Query: 428 YGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII--DNTS 485 GG+ +G+F PTV+ + + E FGP+++V T F D + N S Sbjct: 371 TGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSV-----TRFTGKDDAVAWANDS 425 Query: 486 QYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 Y L +++ KD A +L++ G +IN + ++ GG + SG Sbjct: 426 DYGLASSVWTKDISKAMRAASRLQY--GCTWINTHFM--LTNEMPHGGIKQSG 474 >4PZ2-A nrPDB Length = 534 Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 119/475 (25%), Positives = 221/475 (46%), Gaps = 34/475 (7%) Query: 90 VLANVTQATEKDVMNAVKAAKDA--KKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAAT 147 V+A+V +A ++DV AV+AA+ A +W + +R I + ADL+ ++ ++ A Sbjct: 78 VIASVAEADKEDVDLAVRAARAAFDHGEWPRMSGSERGRIMARLADLVE-EHAGELAALE 136 Query: 148 MLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYA 207 L GK+ + + RY+ A ++ + G + R G Sbjct: 137 SLDAGKHPAVTRAVDVGNAAGSLRYFAGAADKIHGE--TLKMPGQFQGHTLREPLGVAGV 194 Query: 208 VSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGD 266 + P+NF + + APAL G +V KP++ LS L + ++AG+P GVIN +PG Sbjct: 195 IIPWNFPSTMFAVKVAPALAAGCALVVKPAEQTPLSALYLAQLAKQAGVPDGVINVVPGF 254 Query: 267 PVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLV 326 + + D + FTGST V + + ++ Y E GGK+ +V Sbjct: 255 GPTAGAALASHMDVDMVSFTGSTEVGRLIMKASAESNLKPVYL-------ELGGKSPLIV 307 Query: 327 HPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTS 386 A++ AV + +F +G+ C AASR+Y+ E + F + ++S V Sbjct: 308 FDDADLDMAVELAVGASFFNKGEACVAASRVYVQERVYDRFEERLAERMRSWVV------ 361 Query: 387 ASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQ--YDKSQGWFVGPTV 444 P S + R GP + + +++++ I+ K++ +L GG+ + +G+++ PTV Sbjct: 362 GDPFS--DPRADQGPQVDKAQYERVLSYIDHGKREGAT-LLTGGRPCAPEGKGYYIEPTV 418 Query: 445 IKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYA 504 + D E FGP++ + ++ E I N ++Y L + +D ++ A Sbjct: 419 FTNVKEDMIIAKEEIFGPVMCLMKFKTVE-EAIARA--NDTRYGLGAGVVTRD---LDVA 472 Query: 505 DEKLK-FSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 + ++ AG ++N C A+ S FGG +MSG K G + L +++++++ Sbjct: 473 NRVVRSVRAGVVWVN--CYFAMGSDCPFGGRKMSGF-GKDEGMHALDKYLAVKSV 524 >1WNB-A nrPDB Length = 495 Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 131/497 (26%), Positives = 222/497 (44%), Gaps = 48/497 (9%) Query: 48 RASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVK 107 +A LM+ K L+INGE + E+ P NPA VL + +A+ + V AV+ Sbjct: 18 KAGLMQHK-------LLINGELVSGEGEKQ--PVYNPAT-GDVLLEIAEASAEQVDAAVR 67 Query: 108 AAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELS 167 AA A +W R+ LK AD+I + GK ++ A D I + Sbjct: 68 AADAAFAEWGQTTPKVRAECLLKLADVIEENGQV-FAELESRNCGKPLHSAFNDEIPAIV 126 Query: 168 DFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM 227 D FR++ A L E +G + PL G V +++P+N+ + A APAL Sbjct: 127 DVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPL-GVVASIAPWNYPLMMAAWKLAPALA 185 Query: 228 -GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFT 286 GN VV KPS+ L+ L + ++ P GV+N + G V D + + T Sbjct: 186 AGNCVVLKPSEITPLTALKLAELAKDI-FPAGVVNILFGRGKTVGDPLTGHPKVRMVSLT 244 Query: 287 GSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF 346 GS + + S + R E GGK +V A+I AV+ +R TF + Sbjct: 245 GSIATGEHIISHTASSI--------KRTHMELGGKAPVIVFDDADIE-AVVEGVR-TFGY 294 Query: 347 --QGQKCSAASRLYLPESKSEEFLSDMFGILQS-QNVVPMNTSASPISGGNLRGFMGPVI 403 GQ C+AA R+Y + + + + + + ++ P + S +GP+ Sbjct: 295 YNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTE----------LGPLS 344 Query: 404 HEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI 463 +++ K +E+AK ++++ GG+ K G++ PT++ D + E FGP+ Sbjct: 345 SLAHLERVGKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPV 404 Query: 464 LTVYEYPDTEFNEICDIID--NTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKC 521 ++V T F+ +++ N SQY L +++ KD +L++ G ++N Sbjct: 405 VSV-----TPFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQY--GCTWVNTHF 457 Query: 522 TGAVVSQQWFGGARMSG 538 +VS+ GG ++SG Sbjct: 458 M--LVSEMPHGGQKLSG 472 >3IWK-A nrPDB Length = 503 Score = 123 bits (308), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 128/487 (26%), Positives = 222/487 (45%), Gaps = 41/487 (8%) Query: 63 LVINGE-RIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA-----KKDW 116 L I+GE R+ N+R P NP+ + ++ ++ AT++DV AV AAK A +DW Sbjct: 10 LFIDGEWRVPILNKR--IPNINPST-ENIIGDIPAATKEDVDLAVDAAKRAISRKNGRDW 66 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 R A +L+A + + ++ + GK + +A D + ++ F YY Sbjct: 67 SAASGSLR-ARYLRAIAAKIKEKKDELGKLESIDCGKPLEEALAD-LDDVVACFEYYAGL 124 Query: 177 ASDLYAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANL-IGAPALMGNTVVW 233 A +L ++Q P+ T+ + G V ++P+N+ + A I G + Sbjct: 125 AEELDSKQKAPISLPMDTFKSYILKEPIGVVALITPWNYPFLMATWKIAPALAAGCAAIL 184 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KPS+ A+++ L + +E GLP+GV+N + G + + + D + FTGS+ Sbjct: 185 KPSELASVTCLELGEICKEVGLPRGVLNIVTGLGHEAGASLASHPDVDKISFTGSSAT-- 242 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 S ++ + + E GGK+ +V ++ T+ G F GQ CSA Sbjct: 243 ------GSKIMTTAAQLVKPVSLELGGKSPIVVFEDVDLDKVAEWTVFGCFFTNGQICSA 296 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 SRL + ES + EF+ + ++ + + P+ G +GP++ E + K++ Sbjct: 297 TSRLIVHESIAVEFVDKLVKWAENIKI------SDPLEEGCR---LGPIVSEAQYKKVLN 347 Query: 414 VIEDAKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPD 471 I AK + IL GG+ + +G+FV PT+I E FGP+L V + Sbjct: 348 CISSAKSEGA-TILTGGRRPEHLKKGYFVEPTIITDVTTSMQIWREEVFGPVLAVKTFST 406 Query: 472 TEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWF 531 E E ++ ++T Y L A+ + D + E + L+ AG +IN C Q + Sbjct: 407 EE--EAINLANDT-HYGLGSAVMSNDLERCERLSKALQ--AGIVWIN--CAQPSFIQAPW 459 Query: 532 GGARMSG 538 GG + SG Sbjct: 460 GGIKRSG 466 >5U0M-A nrPDB Length = 497 Score = 122 bits (307), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 127/446 (28%), Positives = 200/446 (44%), Gaps = 35/446 (7%) Query: 97 ATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVY 156 A+ +DV AV+ A+ A W +R A+ +L+ + ++ L GK ++ Sbjct: 45 ASLEDVDAAVREARKAFLAWRRKSLAERQAVIEAFGELLEAN-KEELAHQIGLETGKPLW 103 Query: 157 QAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAI 216 ++ + + + VK ++ + A G +RP G V P+NF Sbjct: 104 ESRTE-VAAMMGKIPISVKAYNERTGHTESDVAGGH-AVLRHRP-HGVVAVFGPYNFPGH 160 Query: 217 AANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVL 275 N PAL+ GNTVV+KPS+ L + + E+AGLP GVIN + G T + L Sbjct: 161 LPNGHIVPALLAGNTVVFKPSELTPGVAELTVRLWEKAGLPDGVINLVQGG--SDTGKCL 218 Query: 276 ADKDF-GALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIG-ETGGKNFHLVHPSANIS 333 A L FTGS+ V L+ + G E +I+ E GG N +V +++ Sbjct: 219 ARHSLIDGLFFTGSSTVGHLLHEQF-GGQPE-------KILALEMGGNNPLIVQNVSDLD 270 Query: 334 HAVLSTIRGTFEFQGQKCSAASRLYLPES-KSEEFLSDMFGILQSQNVVPMNTSASPISG 392 AV ++ F GQ+C+ A RL +P+ K +EFL+ + + V + P Sbjct: 271 GAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEFLARLVEVAARITVAEFDADPQP--- 327 Query: 393 GNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDH 452 FMG VI ++ ++L+K + +L Q G + P ++ A + Sbjct: 328 -----FMGSVISAEAANQLLKAQAAMLEKGATSLLEMKQLKPDTG-LLSPGIVDATGIE- 380 Query: 453 PYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSA 512 EFFGP+LTVY Y F+E ++ +NT +Y L+ I + DRK E+++ A Sbjct: 381 -LEDQEFFGPLLTVYRYKG--FDEALELANNT-RYGLSAGILSDDRKLYNRLVEEVR--A 434 Query: 513 GNFYINDKCTGAVVSQQWFGGARMSG 538 G N TGA S FGG SG Sbjct: 435 GIVNWNRPLTGA-SSAAPFGGVGASG 459 >2QE0-A nrPDB Length = 475 Score = 122 bits (307), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 117/464 (25%), Positives = 204/464 (43%), Gaps = 44/464 (9%) Query: 65 INGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDR 124 +NGE NE ++ PA+ + L +V + ++V +AK A+ W L + +R Sbjct: 9 VNGEWKLSENEIKIY---EPASGAE-LGSVPAMSTEEVDYVYASAKKAQPAWRALSYIER 64 Query: 125 SAIFLKAAD-LISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYY----VKYASD 179 +A K AD L+ K + + + + +G Y++ + + ++ Y ++ + Sbjct: 65 AAYLHKVADILMRDKEKIGAILSKEVAKG---YKSAVSEVVRTAEIINYAAEEGLRMEGE 121 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQT 238 + E+A R G V A+SPFN+ A APAL+ GN + +KP Sbjct: 122 VLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAFKPPTQ 181 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 ++S LL EAGLP GV N I G ++ D ++ + ++FTGST + + + Sbjct: 182 GSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIGERI--- 238 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 GK I+ GGK+ +V A++ + I G F + GQ+C+A R+ Sbjct: 239 -------GKMAGMRPIMLALGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVKRVL 291 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + ES ++E + + + V+ + T +P ++ P+I +S D + +I DA Sbjct: 292 VMESVADELVEKI-----REKVLAL-TIGNPEDDADIT----PLIDTKSADYVEGLINDA 341 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 + K +G + P + D E FGP+L + T E Sbjct: 342 NDKGATAL----TEIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRV--TSVEEAI 395 Query: 479 DIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKC 521 + I N S+Y L +IF D +A A++ G +IN+K Sbjct: 396 E-ISNKSEYGLQASIFTNDFPRAFGIAEQ---LEVGTVHINNKT 435 >4U3W-A nrPDB Length = 505 Score = 122 bits (306), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 138/500 (27%), Positives = 213/500 (42%), Gaps = 60/500 (12%) Query: 65 INGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKK-DWYNLPFYD 123 INGE + FP +P + ++ LA+V +A V +AV+AA A+K W + Sbjct: 28 INGEFVASGTT---FPNLSPVDGRK-LADVCEADAALVDSAVQAAHAAQKAGWRDTTPAQ 83 Query: 124 RSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAE-IDCITELSDF--FRYYVKYASDL 180 R+A K AD I ++ + +AA + G+ V QA +D +++F F V+ AS Sbjct: 84 RAAWLHKIADGIEARFD-EFVAAEVADTGRPVAQARTLDIARGIANFRTFADLVRTASGE 142 Query: 181 YAQQPVESADGT--WNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQ 237 Y + +ADG+ N +PL G + +SP+N + APAL MGN VV KPS+ Sbjct: 143 YFE--THAADGSELINYVTRKPL-GVIGIISPWNLPLLLFTWKVAPALAMGNCVVAKPSE 199 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK-DFGALHFTGSTNVFKSLY 296 S LL V+ + GLP GV N I G + L D A+ FTG + ++ Sbjct: 200 ETPSSATLLAEVMHDVGLPPGVFNLIHGHGQNAAGEFLTRHPDISAITFTGESRTGSTIM 259 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + GV E + E GGKN +V A+ AV +R +F GQ C + R Sbjct: 260 KAVADGVKEVSF--------ELGGKNAAVVFADADFDAAVAGVLRSSFTNAGQVCLCSER 311 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 +Y+ E F++ + Q+ V A+ MGP+I DK++ Sbjct: 312 VYVERPIFERFVAALKEQAQALRVGAPEDPATT---------MGPLISRGHRDKVLSYFR 362 Query: 417 DAKKDPELEILYGGQYD----KSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 A ++ + GG + G FV PT+ + E FGP+ + + D Sbjct: 363 LAVEEGATVVTGGGAPSFGDARDDGAFVMPTIWTGLPDSARCVREEIFGPVCHIAPFDDE 422 Query: 473 EFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW-- 530 E+ + N S Y L +I+ + + G+ TG V W Sbjct: 423 A--EVVKRV-NDSAYGLAASIWTT------------QLARGHRVAKQIETGIVWVNAWFV 467 Query: 531 ------FGGARMSGTDDKAG 544 FGG ++SG + G Sbjct: 468 RDLRTPFGGTKLSGLGREGG 487 >3JZ4-A nrPDB Length = 481 Score = 119 bits (299), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 124/480 (25%), Positives = 216/480 (45%), Gaps = 39/480 (8%) Query: 64 VINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYD 123 +INGE + NN A+ TNPAN + L +V + + A+ AA A W L + Sbjct: 13 LINGEWLDANNGEAI-DVTNPANGDK-LGSVPKMGADETRAAIDAANRALPAWRALTAKE 70 Query: 124 RSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQ 183 R+ I +L+ +++ D+ L QGK + +A+ + I+ + F ++ + +Y Sbjct: 71 RATILRNWFNLM-MEHQDDLARLMTLEQGKPLAEAKGE-ISYAASFIEWFAEEGKRIYGD 128 Query: 184 Q-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAAL 241 P AD + +P+ G A++P+NF A PAL G T+V KP+ Sbjct: 129 TIPGHQADKRLIVIK-QPI-GVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPF 186 Query: 242 SNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQS 301 S L + AG+P GV N + G V +++ ++ L FTGST + + L Sbjct: 187 SALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQL------ 240 Query: 302 GVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPE 361 +E +D ++ E GG +V A++ AV + F GQ C A+RLY+ + Sbjct: 241 --MEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQD 298 Query: 362 SKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKD 421 + F + Q + ++ +G + GP+I E++ K+ + I DA + Sbjct: 299 GVYDRFAEKL-----QQAMSKLHIGDGLDNGVTI----GPLIDEKAVAKVEEHIADA-LE 348 Query: 422 PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII 481 ++ GG+ + G F PT++ + E FGP+ ++ + D D+I Sbjct: 349 KGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDE-----ADVI 403 Query: 482 --DNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW-FGGARMSG 538 N +++ L +A+D + E L++ G IN TG + ++ FGG + SG Sbjct: 404 AQANDTEFGLAAYFYARDLSRVFRVGEALEY--GIVGIN---TGIISNEVAPFGGIKASG 458 >4PXN-A nrPDB Length = 525 Score = 118 bits (296), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 122/474 (25%), Positives = 201/474 (42%), Gaps = 45/474 (9%) Query: 82 TNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTK-YR 140 T+P N+Q V+A V +A+ D ++A DA K W +P R I + D + K + Sbjct: 56 TSPTNNQ-VIAEVVEASVHDYEEGMRACFDAAKTWMAIPAPKRGEIVRQIGDALRAKLHH 114 Query: 141 YDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY-----AQQPVESADGTWNK 195 L + +G+ + I + E+ D Y V + L +++P WN Sbjct: 115 LGRLVSLEMGK---ILPEGIGEVQEIIDMCDYAVGLSRQLNGSIIPSERPNHMMMEVWN- 170 Query: 196 AEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNY----LLMTVL 250 PL G V ++ FNF AL+ GN VVWK + T L ++ +VL Sbjct: 171 ----PL-GVVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKIVASVL 225 Query: 251 EEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRD 310 E+ LP + G ++ + D + FTGST + ++ + Sbjct: 226 EKNNLPGAIFTSFCGG-TEIGQAIALDIRIPLVSFTGSTRAGLMVQQQVSA--------R 276 Query: 311 YPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSD 370 + + + E G N +V A+I AV S + GQ+C+ RL L E+ + FL Sbjct: 277 FGKCLLELSGNNAIIVMDDADIQLAVRSVLFAAVGTAGQRCTTCRRLILHENIYQTFLDQ 336 Query: 371 MFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGG 430 + + + + P+ G L +GP+ S + +K I+ K +IL+GG Sbjct: 337 LVEVYKQVRI------GDPLEKGTL---LGPLHTPASKENFLKGIQTIKSQGG-KILFGG 386 Query: 431 QYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALT 490 +S+G FV PT+++ P P + E FGP+L V ++ E + I+N+ L+ Sbjct: 387 SAIESEGNFVQPTIVEIT-PSAPVVKEELFGPVLYVMKF--QTLKEAIE-INNSVPQGLS 442 Query: 491 GAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544 +IF K I G +N GA + FGG + +G +AG Sbjct: 443 SSIFTKRPDIIFKWLGPHGSDCGIVNVNIPTNGAEIGGA-FGGEKATGGGREAG 495 >4I8Q-A nrPDB Length = 514 Score = 117 bits (294), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 124/491 (25%), Positives = 218/491 (44%), Gaps = 39/491 (7%) Query: 79 FPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA--KKDWYNLPFYDRSAIFLKAADLIS 136 P NPA ++++ ++ AT +DV AV+AA+ A + DW + R A +L+A Sbjct: 41 IPIINPAT-EEIIGDIPAATAEDVDIAVEAARKAIARDDWGSTTGAQR-AKYLRAIAAKV 98 Query: 137 TKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQ--PVESADGTWN 194 + + + L GK +Y++ D + +++ F YY A L +++ PV ++ Sbjct: 99 LEKKSVLATLESLDSGKTLYESAAD-MDDVAGCFEYYAGLAEALDSRRMTPVNLNSDSYK 157 Query: 195 KAEYRPLEGFVYAVSPFNFTAIAANL-IGAPALMGNTVVWKPSQTAALSNYLLMTVLEEA 253 R G V ++P+N+ + A + G + KPS+ A+++ L + E Sbjct: 158 SYVLREPLGVVGLITPWNYPLLMAIWKVAPALAAGCAAILKPSELASITCLELGEICREI 217 Query: 254 GLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPR 313 GLP G +N + G + + + + FTGS G S ++ + Sbjct: 218 GLPSGALNILTGLGPEAGGPLASHPHVDKISFTGS--------GPTGSKIMTAAAQLVKP 269 Query: 314 IIGETGGKNFHLVHPSA-NISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMF 372 + GGK+ +V N+ A T+ G F GQ CSA SRL + E+ + F+ + Sbjct: 270 VSLALGGKSPIVVFDDIDNLDIAAEWTLFGIFANTGQVCSATSRLIVQENIASAFMDRLL 329 Query: 373 GILQSQNVV-PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQ 431 ++ + P+ +GPV+ ++K++K I +AK + IL GG+ Sbjct: 330 KWTKNIKISDPLEEDCK----------LGPVVSAGQYEKVLKFISNAKSEGA-TILCGGE 378 Query: 432 YDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYAL 489 + +G++V PT+I E FGP+L V + TE I + N ++Y L Sbjct: 379 RPQHLKKGYYVQPTIITDVNTSMEIWKEEVFGPVLCVKTF-KTEEQAI--ELANDTKYGL 435 Query: 490 TGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNIL 549 A+ +KD K E + F G +IN C+ ++ +GG + SG G L Sbjct: 436 GAAVMSKDVKRCERFTK--AFQTGIIWIN--CSQPTFNELPWGGKKRSGFGRDLGKWG-L 490 Query: 550 SRFVSIRNTKE 560 F++I+ E Sbjct: 491 ENFLNIKQVTE 501 >6MVR-A nrPDB Length = 767 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 134/472 (28%), Positives = 210/472 (44%), Gaps = 56/472 (11%) Query: 78 LFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLIST 137 LF NPA Q LA V+QAT+ DV AVKAA+ A+ W R+ + A L+ Sbjct: 47 LFATVNPAT-GQTLAQVSQATQADVDAAVKAARKAQPAWAK-DGAARARVLYALARLLQK 104 Query: 138 KYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAE 197 R + T L GK + +A + F ++ YA + + P + Sbjct: 105 HARLFAVLET-LDNGKPIREARDIDVPLAQRHFYHHAGYAQLMGTEMP-----------D 152 Query: 198 YRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLP 256 PL G V P+NF + APAL MGNTVV KP++ L+ L + +AG+P Sbjct: 153 RAPL-GVCGQVIPWNFPLLMLAWKIAPALAMGNTVVLKPAEWTPLTALLFADICGQAGVP 211 Query: 257 KGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIG 316 GV+N + GD +++ + FTGST V + + ++ GK Sbjct: 212 AGVVNIVTGD--GAVGEMIVTAQVDKVAFTGSTAVGRRIR---EATAGTGKALSL----- 261 Query: 317 ETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQ 376 E GGK ++V A+I AV + + QGQ C A SRL + E ++ F + + + Sbjct: 262 ELGGKGPYVVCDDADIDSAVEGLVDAIWFNQGQVCCAGSRLLVQEGIADVFHAKLRARMD 321 Query: 377 SQNVV-PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKS 435 S + P++ +G ++H D+L +V + + + E+ Q Sbjct: 322 SLRIGDPLDKCID----------IGAMVHP---DQLARVRDMVAANTDGEVY---QTAVP 365 Query: 436 QGWFVGPTVIKAKRPDHPYMSTEFFGPIL--TVYEYPDTEFNEICDIIDNTSQYALTGAI 493 G + PT+I P P M E FGP+L T + P E +I +NT+ Y L ++ Sbjct: 366 AGCYYPPTLISGLAPASPLMQQEIFGPVLVSTTFRTP----AEAVEIANNTA-YGLAASV 420 Query: 494 FAKDRK-AIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544 ++++ A++ A K AG +IN T + + FGG R SG + G Sbjct: 421 WSENVNLALDLAP---KLVAGIVWING--TNMMDAAAPFGGVRESGFGREGG 467 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 55/222 (24%), Positives = 90/222 (40%), Gaps = 38/222 (17%) Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLA--- 145 ++L + + + KD+ NAV+A +A W + R+ I + +S R D A Sbjct: 528 KLLGHASLSNRKDLRNAVEA-MNAASGWSRTTGHLRAQILYFIGENLSA--RADEFANRI 584 Query: 146 ATMLGQ-GKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGF 204 M G+ GK A ID + + + Y DG + + PL G Sbjct: 585 KDMTGKDGKAEVAASIDRLFSAAAWADKY----------------DG---QVKGVPLRGV 625 Query: 205 VYAV-SPFNFTAI----AANLIG-----APAL-MGNTVVWKPSQTAALSNYLLMTVLEEA 253 A+ P I AA L+G APA+ MGN V S+ L+ VL+ + Sbjct: 626 ALAMKEPVGKIGILCPDAAPLLGLVSLMAPAIAMGNRVTLAASEAFPLAATDFYQVLDTS 685 Query: 254 GLPKGVINFIPGDPVQVTDQVLADKDFGAL-HFTGSTNVFKS 294 +P GV+N + G + + + D A+ +G V ++ Sbjct: 686 DVPAGVVNILTGAHADLAEPMARHLDLDAVWGLSGHAQVIEA 727 >3TY7-A nrPDB Length = 478 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 119/494 (24%), Positives = 209/494 (42%), Gaps = 71/494 (14%) Query: 65 INGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDR 124 INGE + ++N NPA ++V+ V + + DV AV+AA D ++ + +R Sbjct: 12 INGEWV-ESNSNETIEVINPAT-EEVIGKVAKGNKADVDKAVEAADDVYLEFRHTSVKER 69 Query: 125 SAIFLKAADLISTKYR----------YDMLAATMLGQGKNVYQAEID---CITELSDFFR 171 A+ D I +Y D L A + + YQ ++ + D + Sbjct: 70 QALL----DKIVKEYENRKDDIVQAITDELGAPLSLSERVHYQMGLNHFVAARDALDNYE 125 Query: 172 YYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNT 230 + + DL ++ + G ++P+NF +L A A G+ Sbjct: 126 FEERRGDDLVVKEAI----------------GVSGLITPWNFPTNQTSLKLAAAFAAGSP 169 Query: 231 VVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTN 290 VV KPS+ + +L + ++ G+PKGV N + GD V + + + FTGS Sbjct: 170 VVLKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGS-- 227 Query: 291 VFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQK 350 G S ++E +D+ ++ E GGK+ ++V +I A +T GQ Sbjct: 228 ------GPTGSKIMEKAAKDFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQV 281 Query: 351 CSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLR---GFMGPVIHEQS 407 C+A +R+ +P + FL++ + S + GN R +GP+I ++ Sbjct: 282 CTAGTRVLVPNKIKDAFLAE------------LKEQFSQVRVGNPREDGTQVGPIISKKQ 329 Query: 408 FDKLVKVIEDAKKDPELEILYGGQYDK---SQGWFVGPTVIKAKRPDHPYMSTEFFGPIL 464 FD++ I ++ E+ YGG +G+F PT+ E FGP++ Sbjct: 330 FDQVQNYINKGIEEG-AELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVM 388 Query: 465 TVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGA 524 +V Y D +E I ++T +Y L G + KD++ + ++ AG IN+ Sbjct: 389 SVITYND--LDEAIQIANDT-KYGLAGYVIGKDKETLHKVARSIE--AGTVEINEAGRKP 443 Query: 525 VVSQQWFGGARMSG 538 + FGG + SG Sbjct: 444 DLP---FGGYKQSG 454 >2JG7-A nrPDB Length = 510 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 122/472 (25%), Positives = 202/472 (42%), Gaps = 46/472 (9%) Query: 84 PANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDM 143 PAN++ + A VTQAT + V+ ++A K W ++P R I + D + K + + Sbjct: 42 PANNEPI-ARVTQATLAEYEETVQKTREAWKMWADIPAPKRGEIVRQIGDALRKKIKV-L 99 Query: 144 LAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD-----LYAQQPVESADGTWNKAEY 198 + L GK +Y + + E D Y V + L +++P + WN Sbjct: 100 GSLVSLEMGK-IYVEGVGEVQEYVDVCDYAVGLSRMIGGPVLPSERPGHALIEQWNPV-- 156 Query: 199 RPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNY----LLMTVLEEA 253 G V ++ FNF A AL GN +WK + T L++ ++ VLE+ Sbjct: 157 ----GLVGIITAFNFPVAVYGWNNAIALTCGNVCLWKGAPTTPLTSVAVTKIVAEVLEQN 212 Query: 254 GLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPR 313 LP + + G + + D+ L FTGST+V K + +Q + R Sbjct: 213 NLPGAICSMTCGG-ADIGTAMAKDERVDLLSFTGSTHVGKMVAMMVQ--------ERFGR 263 Query: 314 IIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFG 373 + E GG N +V A+++ V S + + GQ+C+ RL L ES + + Sbjct: 264 KLLELGGNNAIIVFEDADLNLVVPSAVFASVGTAGQRCTTTRRLMLHESVHDAVVER--- 320 Query: 374 ILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYD 433 I ++ V + P + GP+ +Q+ D+ + IE AK+ ++ GG+ Sbjct: 321 IAKAYKQVRIGDPWDPST------LYGPLHTKQAVDQYLAAIEQAKQQGG-TLVCGGKVM 373 Query: 434 KSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAI 493 G +V PT+I D P + TE F PIL V ++ + E +N Q L+ +I Sbjct: 374 DRPGNYVEPTIITGLAHDAPIVHTETFVPILYVLKF---KTEEEAFAWNNEVQQGLSSSI 430 Query: 494 FAKDRKAIEYADEKLKFSAGNFYINDKCTGAVV-----SQQWFGGARMSGTD 540 F KD + G +N +GA + ++ GG R SG+D Sbjct: 431 FTKDLGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSD 482 >5TJR-A nrPDB Length = 531 Score = 113 bits (282), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 137/533 (25%), Positives = 221/533 (41%), Gaps = 47/533 (8%) Query: 55 KSSSLEVPLVINGERIYDNNERA-LFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK 113 K S + +I GE I D A +F NP+ + V V A + + A+ AAK A Sbjct: 31 KGSMTLIKHLIGGELIADTGRTADVF---NPSTGEAV-RKVPLADRETMQQAIDAAKAAF 86 Query: 114 KDWYNLPFYDRSAIFLKAADLI-STKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRY 172 W N P R+ + + L+ + + R L + G+ E+ E ++ Sbjct: 87 PAWRNTPPAKRAQVLFRFKQLLEANEERIVKLISEEHGKTIEDAAGELKRGIENVEYATA 146 Query: 173 YVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTV 231 + Y++ + D W+ +++P+ G V ++PFNF A+ + A+ GNT Sbjct: 147 APEILKGEYSRNVGPNID-AWS--DFQPI-GVVAGITPFNFPAMVPLWMYPLAIACGNTF 202 Query: 232 VWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNV 291 + KPS+ S L+ + EAGLPKGV+N + GD V D ++ + AL F GST + Sbjct: 203 ILKPSERDPSSTLLIAELFHEAGLPKGVLNVVHGDKGAV-DALIEAPEVKALSFVGSTPI 261 Query: 292 FKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKC 351 + +Y G GK R+ G KN ++ P A++ +AV + + + G++C Sbjct: 262 AEYIY---SEGTKRGK-----RVQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERC 313 Query: 352 SAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGF-MGPVIHEQSFDK 410 A S + D Q +VP I G G MGP++ + DK Sbjct: 314 MAISVAVC--------VGDQIADALVQKLVP-QIKGLKIGAGTSCGLDMGPLVTGAARDK 364 Query: 411 LVKVIEDAKKDPELEILYGGQYD---KSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVY 467 + I+ ++ G Y G+F+G T+ P+ E FGP+L + Sbjct: 365 VTGYIDTGVAQGAELVVDGRGYKVAGHENGFFLGGTLFDRVTPEMTIYKEEIFGPVLCIV 424 Query: 468 EYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIE-YADEKLKFSAGNFYINDKCTGAVV 526 E E +I N +Y IF +D +A + DE G +N V Sbjct: 425 RVNSLE--EAMQLI-NDHEYGNGTCIFTRDGEAARLFCDE---IEVGMVGVNVPLPVPVA 478 Query: 527 SQQWFGGARMSGTDDKAGGPNILSRFVSIRNT------KENFYELTDFKYPSN 573 + G R D A GP+ + RF + R + +E F +PSN Sbjct: 479 YHSFGGWKRSLFGDLHAYGPDGV-RFYTKRKAITQRWPQRKSHEAAQFAFPSN 530 >4O5H-A nrPDB Length = 511 Score = 112 bits (280), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 128/468 (27%), Positives = 197/468 (42%), Gaps = 42/468 (8%) Query: 82 TNPANHQQVLANVTQATEKDVMNAVKAAK---DAKKDWYNLPFYDRSAIFLKAADLISTK 138 NPA+ V+A V +A E+DV AV AA+ DA W DR + L ADLI Sbjct: 51 VNPADGT-VIARVPEADERDVQQAVAAARRAFDAGP-WRTAKTTDRERLMLVLADLIEAN 108 Query: 139 YRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY-----AQQPVESADGTW 193 R ++ L GK V A+ + + FRY +A+ + A P + Sbjct: 109 AR-ELAEIESLDNGKPVMVAQGLDVAMAAQCFRYMAGWATKIEGSVIDAGMPYLPDSEIF 167 Query: 194 NKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEE 252 P+ G V A+ P+NF + A APAL G TVV KP++ LS L +++ Sbjct: 168 AYTRKEPV-GVVGAIIPWNFPLLMAAWKIAPALATGCTVVLKPAEDTPLSALRLGELIQA 226 Query: 253 AGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYP 312 AG P GV+N + G + D + FTGST K++ + Sbjct: 227 AGFPDGVVNIVTGYGHTAGAALSRDPRIDKIAFTGSTQTGKTIG--------HAALDNMT 278 Query: 313 RIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMF 372 R+ E GGK+ +V P ++ A F QGQ C+A SR Y+ + + + Sbjct: 279 RMSLELGGKSPVIVLPDVDLDKAAQGVANAIFFNQGQVCTAGSRAYIHSKVFDGVIERVA 338 Query: 373 GILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQY 432 I S + P A+ I GP++ + +++ I+ + G Sbjct: 339 KIAASLKIGPGMDPATQI---------GPLVSAKQRERVCGYIDSGFGEGARAAAGGRAI 389 Query: 433 DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGA 492 D G+FV PTV+ + E FGP+L + D + + N + Y L + Sbjct: 390 D-GPGFFVEPTVLVDTTQAMRVVREEIFGPVLVAMPFDDV---DTAVQLANDTPYGLGAS 445 Query: 493 IFAKDRKAIEYADEKL--KFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 I++ D AI KL + +AG ++N C + + FGG + SG Sbjct: 446 IWSNDLSAI----HKLVPRIAAGTVWVN--CHSLLDNALPFGGMKQSG 487 >4X0T-A nrPDB Length = 513 Score = 112 bits (279), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 118/470 (25%), Positives = 203/470 (43%), Gaps = 42/470 (8%) Query: 84 PANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDM 143 PAN++ + A V QA+ D VK A++A K W ++P R I + D + K + + Sbjct: 45 PANNEPI-ARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQV-L 102 Query: 144 LAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEG 203 + L GK + + + + E D Y V + + G ++ P+ G Sbjct: 103 GSLVSLEMGKILVEG-VGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPV-G 160 Query: 204 FVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNY----LLMTVLEEAGLPKG 258 V ++ FNF A A++ GN +WK + T +L + ++ VLE+ LP Sbjct: 161 LVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGA 220 Query: 259 VINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGET 318 + + G + + D+ L FTGST V K + +Q + R + E Sbjct: 221 ICSLTCGG-ADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQ--------ERFGRSLLEL 271 Query: 319 GGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDM---FGIL 375 GG N + A++S V S + GQ+C+ A RL++ ES +E ++ + + + Sbjct: 272 GGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQI 331 Query: 376 QSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKS 435 + N N GP+ +Q+ + +E+AKK+ ++YGG+ Sbjct: 332 RVGNPWDPNV------------LYGPLHTKQAVSMFLGAVEEAKKEGG-TVVYGGKVMDR 378 Query: 436 QGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFA 495 G +V PT++ D TE F PIL V+++ + E E+ +N + L+ +IF Sbjct: 379 PGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEE--EVFA-WNNEVKQGLSSSIFT 435 Query: 496 KDRKAIEYADEKLKFSAGNFYINDKCTGAVV-----SQQWFGGARMSGTD 540 KD I G +N +GA + ++ GG R SG+D Sbjct: 436 KDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSD 485 >3RH9-A nrPDB Length = 506 Score = 111 bits (277), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 132/517 (25%), Positives = 215/517 (41%), Gaps = 45/517 (8%) Query: 59 LEVPLVIN-----GERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK 113 +E PL+ N G R D+ A F NPA V+A V E+DV+ AV+A + A Sbjct: 4 IESPLLENLTGYIGGRWKDSAGGATFDVYNPATGS-VIAKVPSMPEEDVVAAVEAGQSAL 62 Query: 114 KDWYNLPFYDRSAIFLKAAD-LISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRY 172 + P R D L + + G+ Q E+D + FF Y Sbjct: 63 RLTNPWPIETRRKWLEDIRDGLKENREEIGRILCMEHGKPWKEAQGEVD---YAAGFFDY 119 Query: 173 YVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNF-TAIAANLIGAPALMGNT 230 K+ S L + P + D TW YRP+ G + P+NF + A + A G Sbjct: 120 CAKHISALDSHTIPEKPKDCTWT-VHYRPV-GVTGLIVPWNFPIGMIAKKLSAALAAGCP 177 Query: 231 VVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTN 290 V KP+ L+ +V+++ LP G++N + G + + KD L FTGST Sbjct: 178 SVIKPASETPLTMIAFFSVMDKLDLPDGMVNLVMGKASVIGKVLCEHKDVPMLSFTGSTE 237 Query: 291 VFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQK 350 V + L + ++ E GG +V A++ A + I F GQ Sbjct: 238 VGRKL--------IVDTAEQVKKLALELGGNAPFIVFDDADLEAAADNLIANKFRGGGQT 289 Query: 351 CSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDK 410 C A+R+++ E ++D FG ++ V M G ++ GP+I++Q FDK Sbjct: 290 CVCANRIFVHEK-----VADAFGQKLAERVNKMTVGDGMNDGIDI----GPLINKQGFDK 340 Query: 411 LVKVIEDAKKDPELEILYGGQ-YDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEY 469 + + ++DA D ++ G Q + G F PTV++ + E FGP++ + + Sbjct: 341 VKRHLQDA-LDKGASLVAGKQPAELGDGLFFPPTVVQGVDREMCCYQEETFGPLVPMALF 399 Query: 470 PDTEFNEICDIID--NTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVS 527 E ++ID N +++ L +F D + + L+F ++ Sbjct: 400 RTEE-----EVIDAGNDTEFGLASYVFTADAERAQRVAAGLRFG----HVGWNTGTGPTP 450 Query: 528 QQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 + FGG + SG + GG L FV + F E Sbjct: 451 EAPFGGMKASGI-GREGGLEGLFEFVEAQTVPRGFAE 486 >6B4R-B nrPDB Length = 497 Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 132/503 (26%), Positives = 217/503 (43%), Gaps = 43/503 (8%) Query: 43 DWDLLRASLMKFKSSSLEVPLVINGERIYDNNERA-LFPQTNPANHQQVLANVTQATEKD 101 DW+ RA +K + + +NGE Y N F +P + + LA V D Sbjct: 8 DWEA-RAKDLKIEGRAF-----VNGE--YSNAASGETFDCLSPVDGR-FLAKVASCDLAD 58 Query: 102 VMNAVKAAKDA--KKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAE 159 AVK A++A W L R ++ ADL+ L T L GK + + Sbjct: 59 AEQAVKVARNAFDSGAWSRLAPAKRKQTMIRFADLLLENAEELALLET-LDMGKPISDSL 117 Query: 160 IDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAAN 219 + ++ R+ + +Y + + P+ G V A+ P+NF + + Sbjct: 118 HIDVASAANSLRWSAEAIDKIY-DEVAATPHAELGLVTREPV-GVVAAIVPWNFPLLMSC 175 Query: 220 LIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK 278 PAL GN+V+ KPS+ + L+ + + EAG+PKGV N +PG V + Sbjct: 176 WKLGPALATGNSVILKPSEKSPLTAIRIAQLAVEAGIPKGVFNVLPGYGHTVGKALALHM 235 Query: 279 DFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLS 338 D L FTGST + K L +V + R+ E GGK+ ++V A A Sbjct: 236 DVDTLVFTGSTKIAKQL-------MVYAGESNMKRVWLEAGGKSPNIVFADAPDLKAAAE 288 Query: 339 TIRGTFEF-QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRG 397 G F QG+ C+A SRL + S ++FL + L+ P N P+ + Sbjct: 289 AAAGAIAFNQGEVCTAGSRLLVERSIKDKFLPLVIEALKGWK--PGN----PL---DPET 339 Query: 398 FMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQ--YDKSQGWFVGPTVIKAKRPDHPYM 455 +G ++ Q + ++ IE D +++ GG+ +++ G +V PT+ Sbjct: 340 NVGALVDTQQMNTVLSYIEAGHNDGA-KLVAGGKRTLEETGGTYVEPTIFDGVTNAMKIA 398 Query: 456 STEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNF 515 E FGP+L+V E+ D E E I ++T Y L A++ + + L+ AG+ Sbjct: 399 REEIFGPVLSVIEFEDAE--EAVRIANDTP-YGLAAAVWTSNLSKAHLTAKALR--AGSV 453 Query: 516 YINDKCTGAVVSQQWFGGARMSG 538 ++N G + + FGG + SG Sbjct: 454 WVNQYDGGDMTAP--FGGFKQSG 474 >6FK3-A nrPDB Length = 536 Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 134/528 (25%), Positives = 217/528 (41%), Gaps = 55/528 (10%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 ++LE ++ GE + E L + NP++ + V+A +A + V A A++A + Sbjct: 15 GNTLEFGHLVGGEEVL---EGPLLERRNPSDREDVVARFPEADKDLVRKAALKAREAFAE 71 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQ-GKNVYQAEIDCITELSDFFRYYV 174 W P R + ++ + L M+ + GK +A D + E D ++ Sbjct: 72 WSRTPAPIRGQVLFNLVKILEREK--PTLTRLMVREVGKTPKEAAGD-VQEAIDTALFFA 128 Query: 175 KYASDLYAQQ-PVESADGTWNKAEY---RPLEGFVYAVSPFNFTAIAANLIGAPA-LMGN 229 LY Q P E D K + RPL G V ++ NF + PA L GN Sbjct: 129 SEGRRLYGQTVPSEMRD----KELFTFRRPL-GVVGIITAGNFPIAVPSWKLIPAVLTGN 183 Query: 230 TVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQ----VLADKDFGALHF 285 TVVWKPS+ A +++ + EEAGLP GV+N + G T Q ++ + F F Sbjct: 184 TVVWKPSEDAPTLSFVFAKLFEEAGLPPGVLNVVFGGGKGSTGQWMVELMDEGLFQKFAF 243 Query: 286 TGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFE 345 TGST V + + G V G+ P + E GGKN +V A++ AV F Sbjct: 244 TGSTQVGRWI------GEVAGRNLIRPTL--ELGGKNPLVVMRDADLDLAVEGAWWSAFA 295 Query: 346 FQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHE 405 GQ+C++A + + EEF +++ V +P+ + GP I+E Sbjct: 296 TGGQRCTSAGNILVDAPIYEEFKRRFLERVEATLV------GNPLLHPEVT--YGPFINE 347 Query: 406 QSFDKLVKVIEDAKKDPELEILYGGQY-----------DKSQGWFVGPTVIKAKRPDHPY 454 + F + + + + + G+ D G + PTV + RP Sbjct: 348 RFFARWQEHYRVGEAEGARLLFGRGRITRENPYPRFLGDPEAGLYGWPTVWEV-RPGTRL 406 Query: 455 MSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGN 514 + E FGP + + + E + N++ Y L+ AI+ R K+ AG Sbjct: 407 FTEEVFGPTINLVKVDGI---EEAIAVANSTPYGLSSAIYTNHRHWAYLF--KVGIRAGM 461 Query: 515 FYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENF 562 IN+ GA FGG + SG + G +L + E + Sbjct: 462 TSINNATVGAEAHLP-FGGVKASGNGGRESGIWVLEEYTYWHAVNEEY 508 >5EUY-A nrPDB Length = 491 Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 115/495 (23%), Positives = 225/495 (45%), Gaps = 48/495 (9%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 ++V INGE + + A +T+P + ++ A V ++ +D A+ +A +A K W N Sbjct: 7 MKVANYINGE-FKEPSTGAFQVKTSPVDGSKI-AEVPRSGREDAREAIDSAFEALKAWAN 64 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQG--KNVYQAEIDCITELSDFFRYYVKY 176 +P R+ K ++ M T+ G G + V+ + F ++ Sbjct: 65 IPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRKVWGEVV--------FTERLIQN 116 Query: 177 ASDL---YAQQPVESADGTWNKAEYRPLEGFVYAVSPFNF-TAIAANLIGAPALMGNTVV 232 A++L Y + ++S + ++ +G V ++P+N+ +I+ I +GNTVV Sbjct: 117 AAELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVV 176 Query: 233 WKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVF 292 +KP+ ++ +L+ ++ +AGLPKGV N + G V ++++ K + FTG ++ Sbjct: 177 YKPASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTG 236 Query: 293 KSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCS 352 + + K +G ++ + E GG + ++ ++ +A + + QGQ C+ Sbjct: 237 REIAAK-AAGTLK-------TVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICT 288 Query: 353 AASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLV 412 +A R+ + ++ +++F+ + + V M P + +GP+I+E+ + Sbjct: 289 SAKRIIVHKAVADKFIE------RYVHYVKMLRIDDPRKDEKVD--LGPLINERQVALMK 340 Query: 413 KVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI--LTVYEYP 470 + ++DA +L GG +S G F P + + M E FGP+ + V E Sbjct: 341 EFVDDAVSRGG-RLLIGG---RSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVEND 396 Query: 471 DTEFNEICDIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVVSQQ 529 D + N + Y L+GA+ + +A A+ +G F+IND T S Sbjct: 397 DQAVE-----VANDTDYGLSGAVLTNNVNRAFRIAE---AVESGMFHIND-VTFLEESHV 447 Query: 530 WFGGARMSGTDDKAG 544 FGG + SG + G Sbjct: 448 PFGGIKASGVGREGG 462 >4KNA-A nrPDB Length = 495 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 123/482 (25%), Positives = 202/482 (41%), Gaps = 69/482 (14%) Query: 78 LFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLIST 137 +F NP +++V + A+ DV AV +A+ A W L R I + A L+ Sbjct: 25 VFASRNPGTNERVWEGAS-ASADDVERAVASARRAFAAWSALDLDARCTIVKRFAALLVE 83 Query: 138 KYRYDMLAATMLGQ--GKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNK 195 R + LA TM+G+ GK +++A + + ++ + + ++ ADG Sbjct: 84 --RKEALA-TMIGRETGKPLWEARTE-VASMAAKVDISITAYHERTGEKRAPMADGV-AV 138 Query: 196 AEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAG 254 +RP G V P+NF N PAL+ GNTVV+KPS+ A + + +AG Sbjct: 139 LRHRP-HGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPGVARATVEIWRDAG 197 Query: 255 LPKGVINFIPGDPVQVTDQVLAD-KDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPR 313 LP GV+N + G+ + T LA+ + L FTGS++ L+ ++ P Sbjct: 198 LPAGVLNLVQGE--KDTGVALANHRQIDGLFFTGSSDTGTLLH---------KQFGGRPE 246 Query: 314 II--GETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESK-SEEFLSD 370 I+ E GG N +V +I AV I+ F GQ+C+ A R+ +P + F++ Sbjct: 247 IVLALEMGGNNPLVVAEVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPRGAFGDRFVAR 306 Query: 371 MFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK------------VIEDA 418 + + + P FMG VI ++ +LV +IE Sbjct: 307 LADVASKITASVFDADPQP--------FMGAVISARAASRLVAAQARLVGLGASPIIEMK 358 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 ++DP L + D + + PD E FGP+ + Y D + Sbjct: 359 QRDPALGFVNAAILDVTN---------VRELPDE-----EHFGPLAQIVRYTDLD----- 399 Query: 479 DII--DNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 536 D I N + + L+ + A D +A ++ N+ ++ T S FGGA Sbjct: 400 DAIARANDTAFGLSAGLLADDEQAWHTFRRAIRAGIVNW---NRPTNGASSAAPFGGAGR 456 Query: 537 SG 538 SG Sbjct: 457 SG 458 >6C43-A nrPDB Length = 477 Score = 105 bits (262), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 122/490 (24%), Positives = 215/490 (43%), Gaps = 43/490 (8%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 S++++ L+ING + ER NPA + +L + +A+ V AV+AA +A + Sbjct: 1 SNAMQYQLLINGVLVDGEGERQSV--YNPATGEVIL-EIAEASPAQVDAAVQAADNAFAE 57 Query: 116 WYNLPFYDRSAIFLKAADLIS-TKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYV 174 W R+ LK AD I + L + G K ++ D I + D FR++ Sbjct: 58 WGQTTPKARAECLLKLADSIEQNALEFARLESQNCG--KPLHCVINDEIPAIVDVFRFFA 115 Query: 175 KYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVW 233 A L E +G + P+ G V +++P+N+ + A APAL GN VV Sbjct: 116 GAARCLSGLAAGEYLEGHTSMIRRDPI-GVVASIAPWNYPLMMAAWKLAPALAAGNCVVI 174 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KPS+ L+ L + VL + P GV+N + G V D + + + TGS + Sbjct: 175 KPSEITPLTA-LKLAVLAKDIFPPGVLNVLFGRGQTVGDVLTGHEKVRMVSLTGSIATGE 233 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF--QGQKC 351 + + R E GGK +V A++ AV +R TF F GQ C Sbjct: 234 HILRHTAPAI--------KRTHMELGGKAPVIVFDDADLD-AVAQGVR-TFGFYNAGQDC 283 Query: 352 SAASRLYLPESKSEEFLSDMFGILQSQNV-VPMNTSASPISGGNLRGFMGPVIHEQSFDK 410 +AA R+Y + + + + S + P + S +GP+ + Sbjct: 284 TAACRIYAQRGIYDALVEKLGNAVSSLKMGAPEDESTE----------LGPLSSLAHLKR 333 Query: 411 LVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP 470 + +E+AK + ++ GG + +G++ PT++ + + + E FGP++++ Sbjct: 334 VTAAVEEAKALSHIRVITGGSQTEGKGYYFAPTLLADAKQEDAIVQREVFGPVVSI---- 389 Query: 471 DTEFNEICDIID--NTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQ 528 T F++ ++ N S+Y L +++ +D +L++ G +IN +VS+ Sbjct: 390 -TVFDDEDQVLRWANDSRYGLASSVWTQDVGRAHRLSARLQY--GCTWINTHFM--LVSE 444 Query: 529 QWFGGARMSG 538 GG + SG Sbjct: 445 MPHGGQKQSG 454 >3JU8-A nrPDB Length = 490 Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 124/455 (27%), Positives = 196/455 (43%), Gaps = 54/455 (11%) Query: 97 ATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQ--GKN 154 AT+ D AV AA++A W P R + + A + K R D LA ++G+ GK Sbjct: 41 ATQVDA--AVCAAREAFPAWARRPLEQRIELLERFAATL--KSRADELA-RVIGEETGKP 95 Query: 155 VYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFT 214 ++++ + +T + + V+ + ++ AD T ++P G V P+NF Sbjct: 96 LWESATE-VTSMVNKVAISVQAFRERTGEKSGPLADAT-AVLRHKP-HGVVAVFGPYNFP 152 Query: 215 AIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQ 273 N PAL+ GN VV+KPS+ L + +AGLP GV+N + G + Sbjct: 153 GHLPNGHIVPALLAGNCVVFKPSELTPKVAELTLKAWIQAGLPAGVLNLVQGG-RETGVA 211 Query: 274 VLADKDFGALHFTGST---NVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA 330 + A + L FTGS+ N+ S +G G+ + + E GG N +V A Sbjct: 212 LAAHRGLDGLFFTGSSRTGNLLHSQFG--------GQPQKILAL--EMGGNNPLVVEEVA 261 Query: 331 NISHAVLSTIRGTFEFQGQKCSAASRLYLPESK-SEEFLSDMFGILQSQNVVPMNTSASP 389 ++ AV + I+ F GQ+C+ A RL +P+ + L+ + + + V + +P Sbjct: 262 DLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDALLARLVAVSATLRVGRFDEQPAP 321 Query: 390 ISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIK--- 446 FMG VI + + L+K E +L Q + P ++ Sbjct: 322 --------FMGAVISLSAAEHLLKAQEHLIGKGAQPLLAMTQPIDGAA-LLTPGILDVSA 372 Query: 447 -AKRPDHPYMSTEFFGPILTVYEYPD--TEFNEICDIIDNTSQYALTGAIFAKDRKAIEY 503 A+RPD EFFGP+L V Y D E N +QY L + + R+ E Sbjct: 373 VAERPDE-----EFFGPLLQVIRYSDFAAAIREA-----NATQYGLAAGLLSDSRERFE- 421 Query: 504 ADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 ++ AG N + TGA S FGG SG Sbjct: 422 -QFLVESRAGIVNWNKQLTGAASSAP-FGGIGASG 454 >3VZ0-A nrPDB Length = 459 Score = 102 bits (254), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 111/449 (24%), Positives = 191/449 (42%), Gaps = 41/449 (9%) Query: 95 TQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLIST-KYRYDMLAATMLGQGK 153 T A KD+ + +A K DW R I +AADL+ + + L AT +G+ Sbjct: 25 TPAQMKDITD--RAEHVWKTDWKLRSIAQRKEIVSRAADLLRRDRQHHASLIATEMGKAL 82 Query: 154 NVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNF 213 EID +D +Y A + A P++ G K +PL G +Y + P+NF Sbjct: 83 PDALEEIDVT---ADILSFYANGAEEFLAPTPLKVKTGQ-AKIINQPL-GIIYCIEPWNF 137 Query: 214 TAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTD 272 + P LM GN V+ K + + +AG P G I D Q + Sbjct: 138 PYYQLARVAGPNLMAGNVVIAKHAPNVPQCALAFEKLFHDAGAPVGAYANIFLDNDQ-SA 196 Query: 273 QVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANI 332 +++ D+ + TGS +++ + + + + E GG + +V A++ Sbjct: 197 ELIKDERIRGVALTGSERAGQAVAAQAGAALKKDTM--------ELGGSDAFIVLDDADL 248 Query: 333 SHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDM---FGILQSQNVVPMNTSASP 389 AV + G F GQ C+AA R+ + E + FL + + N + +T+ P Sbjct: 249 DLAVKWAVWGRFANNGQVCTAAKRMIVHEKVYDAFLDGLKTAITRFRIGNPLDRDTTHGP 308 Query: 390 ISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKR 449 +S +LR E + D+ + ++ ++ GG+ +G+F+ PT++ Sbjct: 309 MS--SLRAM------ELALDQTAEAVKGGAT-----LVAGGKRMDRKGFFMEPTILTDVS 355 Query: 450 PDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLK 509 D+P E FGP+ V++ + + N S Y L GA+F++D E E+++ Sbjct: 356 KDNPVFYQEIFGPVAVVHKVAS---EQAAIDLANDSPYGLGGAVFSRDIARAEKVAEQVE 412 Query: 510 FSAGNFYINDKCTGAVVSQQWFGGARMSG 538 G +IN A + FGG + SG Sbjct: 413 --TGMVFINTATAAA--PELPFGGIKNSG 437 >4V6H-A nrPDB Length = 484 Score = 102 bits (253), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 115/464 (24%), Positives = 204/464 (43%), Gaps = 32/464 (6%) Query: 77 ALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLIS 136 A F +PA + L V + + A++AA+ A W +R+AI + DL+ Sbjct: 28 ATFEVFDPATGES-LGTVPKMGAAETARAIEAAQAAWAGWRMKTAKERAAILRRWFDLVI 86 Query: 137 TKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKA 196 D+ QGK + +A+ + I + F ++ + + A + + D Sbjct: 87 ANSD-DLALILTTEQGKPLAEAKGE-IAYAASFIEWFAEEGKRV-AGDTLPTPDANKRIV 143 Query: 197 EYRPLEGFVYAVSPFNF-TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGL 255 + G A++P+NF A+ A +G G +V KP+++ S + + E AG+ Sbjct: 144 VVKEPIGVCAAITPWNFPAAMIARKVGPALAAGCPIVVKPAESTPFSALAMAFLAERAGV 203 Query: 256 PKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRII 315 PKGV++ + GDP + ++ ++ L FTGST V + L + V ++ Sbjct: 204 PKGVLSVVIGDPKAIGTEITSNPIVRKLSFTGSTAVGRLLMAQSAPTV--------KKLT 255 Query: 316 GETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGIL 375 E GG +V A++ AV I + GQ C +R ++ E + F +D Sbjct: 256 LELGGNAPFIVFDDADLDAAVEGAIASKYRNNGQTCVCTNRFFVHERVYDAF-ADKLAAA 314 Query: 376 QSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKS 435 S+ V T SG L GP+I+E + K+ I DA + G ++ Sbjct: 315 VSKLKVGRGTE----SGATL----GPLINEAAVKKVESHIADALAKGASLMTGGKRHALG 366 Query: 436 QGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFA 495 G+F PTV+ +PD E FGP+ ++ + E E+ + ++T ++ L +++ Sbjct: 367 HGFFE-PTVLTGVKPDMDVAKEETFGPLAPLFRFASEE--ELVRLANDT-EFGLAAYLYS 422 Query: 496 KDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW-FGGARMSG 538 +D + E L++ G IN TG + ++ FGG + SG Sbjct: 423 RDIGRVWRVAEALEY--GMVGIN---TGLISNEVAPFGGVKQSG 461 >3K2W-A nrPDB Length = 497 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 115/441 (26%), Positives = 190/441 (43%), Gaps = 43/441 (9%) Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM 148 +V+ + + D NA++ A+ A+K W L R + A+ I + +LA + Sbjct: 39 KVIGEIPAGCKADAENALEVAQAAQKAWAKLTARTRQNMLRTFANKI--RENKHILAPML 96 Query: 149 LG-QGKNVYQAEIDCITELSDFFRYYVKYASD--LYAQQPVESADGTWNKAEYRPL-EGF 204 + QGK + AE++ D ++ Y D L + + +D K + G Sbjct: 97 VAEQGKLLSVAEMEV-----DVTATFIDYGCDNALTIEGDILPSDNQDEKIYIHKVPRGV 151 Query: 205 VYAVSPFNF-TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFI 263 V ++ +NF A+A IG + GNT+V KP+Q L+ L + +EAGLP GV+N I Sbjct: 152 VVGITAWNFPLALAGRKIGPALITGNTMVLKPTQETPLATTELGRIAKEAGLPDGVLNVI 211 Query: 264 PGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNF 323 G V + + TGST K +Y +Y ++ E GGK Sbjct: 212 NGTGSVVGQTLCESPITKMITMTGSTVAGKQIYK------TSAEY--MTPVMLELGGKAP 263 Query: 324 HLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV-P 382 +V A++ A + G F GQ C+ RLY+ S +EF++ +++ V P Sbjct: 264 MVVMDDADLDKAAEDALWGRFANCGQVCTCVERLYVHASVYDEFMAKFLPLVKGLKVGDP 323 Query: 383 MNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVG- 441 M+ + MGP +++ D + ++ +A K + GG+ +G+ G Sbjct: 324 MDADSQ----------MGPKCNQREIDNIDHIVHEAIKQGAT-VATGGKTATVEGFEGGC 372 Query: 442 ---PTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN-EICDIIDNTSQYALTGAIFAKD 497 PTV+ + D+ + E FGPIL + + E E C N S Y L+ + + Sbjct: 373 WYEPTVLVDVKQDNIVVHEETFGPILPIVKVSSMEQAIEFC----NDSIYGLSAYVHTQS 428 Query: 498 RKAIEYADEKLKFSAGNFYIN 518 I A L+ G YIN Sbjct: 429 FANINQAISDLEV--GEVYIN 447 >5X5U-A nrPDB Length = 505 Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 127/504 (25%), Positives = 212/504 (42%), Gaps = 48/504 (9%) Query: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFY 122 L+I+GE + D NPA + + V A D+ A+ AA+ + W +P + Sbjct: 35 LLIDGEWV-DAASGKTIDVVNPATGKPI-GRVAHAGIADLDRALAAAQSGFEAWRKVPAH 92 Query: 123 DRSAIFLKAADLISTKYRYDMLAATMLG-QGKNVYQAEIDCITELSDFFRYYVKYASDLY 181 +R+A KAA L+ + R D +A M QGK + +A ++ ++ +D ++ +Y Sbjct: 93 ERAATMRKAAALV--RERADAIAQLMTQEQGKPLTEARVEVLSA-ADIIEWFADEGRRVY 149 Query: 182 AQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTA--IAANLIGAPALMGNTVVWKPSQTA 239 + G P+ G V A +P+NF + L A A + +V P +T Sbjct: 150 GRIVPPRNLGAQQTVVKEPV-GPVAAFTPWNFPVNQVVRKLSAALATGCSFLVKAPEETP 208 Query: 240 ALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKI 299 A S L+ +AG+P GVI + GDP +++ ++ + FTGST V K L Sbjct: 209 A-SPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGKQLAS-- 265 Query: 300 QSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYL 359 + G + R E GG +V A+++ AV + F GQ C + +R + Sbjct: 266 ----LAGLHMK--RATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFLV 319 Query: 360 PESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLR--GFMGPVIHEQSFDKLVKVIED 417 S +EF + + V G L +G + + + + VI++ Sbjct: 320 HNSIRDEFTRALVKHAEGLKV-----------GNGLEEGTTLGALANPRRLTAMASVIDN 368 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 A+K I GG+ S+G F PTVI D + E FGP+ + + E I Sbjct: 369 ARKV-GASIETGGERIGSEGNFFAPTVIANVPLDADVFNNEPFGPVAAIRGFDKLE-EAI 426 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW----FGG 533 + N + L G F + + ++L+ G +IN T W FGG Sbjct: 427 AEA--NRLPFGLAGYAFTRSFANVHLLTQRLEV--GMLWINQPAT------PWPEMPFGG 476 Query: 534 ARMSGTDDKAGGPNILSRFVSIRN 557 + SG + GGP L ++ ++ Sbjct: 477 VKDSGYGSE-GGPEALEPYLVTKS 499 >6DBB-A nrPDB Length = 511 Score = 100 bits (248), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 115/462 (24%), Positives = 194/462 (41%), Gaps = 32/462 (6%) Query: 91 LANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLG 150 LA + T D + AA DA W +P R + +++ +++ ++ L Sbjct: 41 LATLAVDTPADAERKIDAAHDAFLKWRTVPAPVRGELVRVFGNVLR-EHKAELGRLVTLE 99 Query: 151 QGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSP 210 GK + + + E+ D + V + LY G + P+ G +S Sbjct: 100 AGK-ITSEGLGEVQEMIDICDFAVGLSRQLYGLTIASERPGHRMMETWHPI-GVCGVISA 157 Query: 211 FNF-TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPG-DPV 268 FNF A+ A + G++VVWKPS+ L+ +L++A + PG P Sbjct: 158 FNFPVAVWAWNAALAFVCGDSVVWKPSEKTPLTAIACHVLLQKA--LREFEKTHPGVAPA 215 Query: 269 QVTDQVLADKDFGALHFTGSTNV-FKSLYGKIQSG--VVEGKYRDYPRIIGETGGKNFHL 325 ++ VL +D G + T S V S G ++ G V + + R I E GG N + Sbjct: 216 ELGQLVLGMRDVGEV-LTASKKVPVVSATGSVRMGQEVAKVLSQRLARGILELGGNNGMI 274 Query: 326 VHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNT 385 V PSA++ V + GQ+C+ RL + S E+ L + S V Sbjct: 275 VAPSADLDLVVRAVTFAAVGTAGQRCTTLRRLIVHRSLVEQLLPRIEKAYASVKV----- 329 Query: 386 SASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYD--KSQGWFVGPT 443 +P+ G L +GP++ SFD + K + DA++ E+ G + D + ++V P Sbjct: 330 -GNPLEEGTL---VGPLVDRASFDAMQKALADAREQGG-EVKGGERVDVGHADAYYVRPA 384 Query: 444 VIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEY 503 +++ + + E F PIL V Y + F++ D + N L+ AIF D + E Sbjct: 385 IVRMPK-QSAVVERETFAPILYVMVYDN--FDDAID-VHNAVPQGLSSAIFTNDMREAEQ 440 Query: 504 ADEKLKFSAGNFYINDKCTGAVV-----SQQWFGGARMSGTD 540 G +N +GA + ++ GG R SG+D Sbjct: 441 FMSAAGSDCGIVNVNIGTSGAEIGGAFGGEKETGGGRESGSD 482 >3EK1-A nrPDB Length = 504 Score = 99.4 bits (246), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 110/438 (25%), Positives = 187/438 (42%), Gaps = 32/438 (7%) Query: 50 SLMKFKSSSL-EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKA 108 S++ K SL + ++NG R D + TNPA+ V+ V + + A+ A Sbjct: 21 SMLALKDPSLLKSQCLVNG-RWIDAADGTTIKVTNPADGS-VIGTVPSLSVATIKEAIDA 78 Query: 109 AKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLG-QGKNVYQAEIDCITELS 167 + A W +R+ I K DLI D +A M QGK + +A + + S Sbjct: 79 SAKALSGWAAKTAKERAGILRKWFDLIIANA--DDIALIMTSEQGKPLAEARGEVLYAAS 136 Query: 168 DFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM 227 F ++ + A +Y +G +P+ G A++P+NF A APAL Sbjct: 137 -FIEWFAEEAKRVYGDTIPAPQNGQRLTVIRQPV-GVTAAITPWNFPAAMITRKAAPALA 194 Query: 228 -GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFT 286 G T++ +P+ L+ L + E+AG+P GV+ + G ++ ++ ++ L FT Sbjct: 195 AGCTMIVRPADLTPLTALALGVLAEKAGIPAGVLQIVTGKAREIGAELTSNDTVRKLSFT 254 Query: 287 GSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF 346 GST V + L + + RI E GG +V A++ AV + + Sbjct: 255 GSTEVGRLLMAQCAPTI--------KRISLELGGNAPFIVFDDADLDAAVDGAMVSKYRN 306 Query: 347 QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRG-FMGPVIHE 405 GQ C A+R+Y+ ++F + ++ V G G +GP+I E Sbjct: 307 AGQTCVCANRIYVQRGVYDKFAEKLAAKVKELKV----------GNGTEPGVVIGPMIEE 356 Query: 406 QSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILT 465 ++ K+ IEDA +++ GG+ + G F P ++ D E FGP+ Sbjct: 357 KAITKVKAHIEDAVSKGA-KLITGGK--ELGGLFFEPGILTGVTSDMLVAKEETFGPLAP 413 Query: 466 VYEYPDTEFNEICDIIDN 483 ++ + DTE I D Sbjct: 414 LFAF-DTEEEVIAQANDT 430 >3U4J-A nrPDB Length = 528 Score = 99.0 bits (245), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 130/497 (26%), Positives = 216/497 (43%), Gaps = 55/497 (11%) Query: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA--KKDWYNLP 120 ++++G+ + D + + +P + +V+ +A+ DV AV AA+ A W + Sbjct: 25 MLVDGKSV-DAASGSTIDRVSPGHAGEVVGTWPEASADDVRKAVAAARKAFDAGPWPRMS 83 Query: 121 FYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 +RS + K ADLI + + ++ L GK + QA + I +D + Y A L Sbjct: 84 GAERSRLMFKVADLILAR-QEELALIESLEVGKPIAQARGE-IGFCADLWSYAAGQARAL 141 Query: 181 YAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAAN-----LIGAPALMGNTVVWKP 235 Q D P+ G V ++P+NF I A+ IG+ G TVV KP Sbjct: 142 EGQTHNNIGDDRLGLVLREPV-GVVGIITPWNFPFIIASERVPWAIGS----GCTVVLKP 196 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIP--GDPVQVTDQVLA-DKDFGALHFTGSTNVF 292 S+ + ++ L + EAG+P GV N + GDP QVLA D + + FTGS V Sbjct: 197 SEFTSGTSIRLAELAREAGIPDGVFNVVTGYGDP---AGQVLAEDPNVDMVAFTGSVRVG 253 Query: 293 KSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCS 352 L G+I + R R+ E GGK +V A++ A G + GQ C Sbjct: 254 TKL-GEIAA-------RTVKRVGLELGGKGPQIVFADADLDAAADGIAYGVYHNAGQCCI 305 Query: 353 AASRLYLPESKSEEFLSDMFGILQSQNVV---PMNTSASPISGGNLRGFMGPVIHEQSFD 409 + SRL + E + + + I S+ V P+N R +G +I E + Sbjct: 306 SGSRLLVQEGIRDALMERLLDI--SRKVAFGDPLNE----------RTKIGAMISEAHAE 353 Query: 410 KLVKVIEDAKKDPELEILYGGQ-YDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYE 468 K+ + A E+L GG+ + G + PTV PD E FGP+L+ Sbjct: 354 KVHSYV-TAGITSGAELLLGGERIGREAGLYYAPTVFAGVTPDMSIAREEIFGPVLSTLT 412 Query: 469 YPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKL-KFSAGNFYINDKCTGAVVS 527 + + + N +++ L+ ++++ + +E A + + + AG +IN G Sbjct: 413 FKTADE---AVALANATEFGLSASVWSTN---LETALQTIRRIRAGRCWINSVIDG--TP 464 Query: 528 QQWFGGARMSGTDDKAG 544 + GG + SG + G Sbjct: 465 ELPIGGYKKSGLGRELG 481 >5IUV-A nrPDB Length = 497 Score = 98.2 bits (243), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 116/458 (25%), Positives = 189/458 (41%), Gaps = 37/458 (8%) Query: 89 QVLANVTQATEKDVMNAVKAAKDA--KKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAA 146 ++LA V D AV++A+ A W L R A ++ A L+ L Sbjct: 46 RLLAKVASCDAADAQRAVESARSAFDSGAWSRLAPAKRKATMIRFAGLLEQNAEELALLE 105 Query: 147 TMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVY 206 T L GK + + I + + + LY + D P+ G V Sbjct: 106 T-LDMGKPISDSLGVDIPGGARALSWSGEAIDKLYDEVAATPHD-QLGLVTREPV-GVVA 162 Query: 207 AVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPG 265 A+ P+NF + A PAL GN+VV KPS+ + L+ + + EAG+P GV+N +PG Sbjct: 163 AIVPWNFPLMMACWKLGPALSTGNSVVLKPSEKSPLTAIRIAQLAIEAGIPAGVLNVLPG 222 Query: 266 DPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHL 325 V + D + FTGST + K L ++ + R+ E GGK+ ++ Sbjct: 223 YGHTVGKALALHMDVDTVVFTGSTKIAKQL-------MIYAGESNMKRVWLEAGGKSPNI 275 Query: 326 VHPSANISHAVLSTIRGTFEF-QGQKCSAASRLYLPESKSEEFLS---DMFGILQSQNVV 381 V A A + F QG+ C+A SRL + S + FL + G + N Sbjct: 276 VFADAPDLQAAADSAASAIAFNQGEVCTAGSRLLVERSIKDRFLPMVIEALGTWKPGN-- 333 Query: 382 PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQ-YDKSQGWFV 440 P++ + + +G ++ Q + ++ I D + G Q ++ G +V Sbjct: 334 PLDPATN----------VGALVDTQQMNTVLSYIAAGHTDGARLVAGGKQILQETGGTYV 383 Query: 441 GPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKA 500 PT+ E FGP+L+V + DT I I N + Y L A++ + Sbjct: 384 EPTIFDGVNNAMRIAQEEIFGPVLSVLTF-DTAEEAIQ--IANDTPYGLAAAVWTANLSK 440 Query: 501 IEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 L+ AG+ ++N G + + FGG + SG Sbjct: 441 AHLTARALR--AGSVWVNQYDGGDMTAP--FGGFKQSG 474 >4E4G-A nrPDB Length = 521 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 110/423 (26%), Positives = 191/423 (45%), Gaps = 38/423 (8%) Query: 54 FKSSSLEVPLVINGERIYDNNERA--LFPQTNPANHQQVLANVTQATEKDVMNAVKAAKD 111 F+S E+ I+G+R+ + R +F NPA +V V A++ D+ AV++AK Sbjct: 20 FQSMMYELGHFIDGKRVAGTSGRVSNIF---NPAT-GEVQGTVALASDADLAAAVESAKA 75 Query: 112 AKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQ--GKNVYQAEIDCITELSDF 169 A+ W R+ +F+K L++ A ML + GK + A+ D + L Sbjct: 76 AQPKWAATNPQRRARVFMKFVQLLNDNMNE---LAEMLSREHGKTIDDAKGDIVRGLE-- 130 Query: 170 FRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MG 228 +V L + E A + R G ++PFNF + + APA+ G Sbjct: 131 VCEFVIGIPHLQKSEFTEGAGPGIDMYSIRQPVGIGAGITPFNFPGMIPMWMFAPAIACG 190 Query: 229 NTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGS 288 N + KPS+ L ++ EAGLP G++N + GD V D +L D A+ F GS Sbjct: 191 NAFILKPSERDPSVPIRLAELMIEAGLPAGILNVVNGDKGAV-DAILTHPDIAAVSFVGS 249 Query: 289 TNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQG 348 T + + +YG + + GK R G KN ++ P A++ A + I + G Sbjct: 250 TPIARYVYG---TAAMNGK-----RAQCFGGAKNHMIIMPDADLDQAANALIGAGYGSAG 301 Query: 349 QKCSAAS-RLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQS 407 ++C A S + + E + + + +++S + P + MGPV+ +++ Sbjct: 302 ERCMAISVAVPVGEETANRLIDKLVPMVESLRIGPYTDE---------KADMGPVVTKEA 352 Query: 408 FDKLVKVIEDAKKDPELEILYGGQYDKSQGW----FVGPTVIKAKRPDHPYMSTEFFGPI 463 ++ +I D+ + +++ G+ K QG+ F+G + PD TE FGP+ Sbjct: 353 EQRIRSLI-DSGIEQGAKLVVDGRDFKLQGYENGHFIGGCLFDDVTPDMDIYKTEIFGPV 411 Query: 464 LTV 466 L+V Sbjct: 412 LSV 414 >4LIH-A nrPDB Length = 504 Score = 93.2 bits (230), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 93/354 (26%), Positives = 168/354 (47%), Gaps = 35/354 (9%) Query: 211 FNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIP--GDP 267 +NF + A PAL GN+VV KPS+ + L+ + + EAG+P GV N +P G+P Sbjct: 175 WNFPILMAAWKFGPALAAGNSVVLKPSEKSPLTAIRVAQLAFEAGIPAGVFNVVPGAGEP 234 Query: 268 VQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVH 327 ++ + +D + FTGST V K + + + R E GGK+ ++V Sbjct: 235 GKL---LALHRDVDCIAFTGSTAVGKLI-------MQYAAQSNLKRAWLELGGKSPNIVL 284 Query: 328 PSA-NISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTS 386 P ++ A + F G+ C+A SRL + + F+ + + ++ VP N Sbjct: 285 PDCPDLDRAAQTAAGAIFYNMGEMCTAGSRLLVHRDIKDAFIEKL--VAAARAYVPGNPL 342 Query: 387 ASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYD-KSQGWFVGPTVI 445 +S MG ++ ++++ IE + + L + G + + ++ G++V PTV Sbjct: 343 DPSVS-------MGAIVDGIQLERVLGYIEAGRGEGRL-VTGGARVNAETGGFYVEPTVF 394 Query: 446 KAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYAD 505 + K PD E FGP+L+V + D +E I ++T +Y L A++ + Sbjct: 395 EVK-PDAKIAREEIFGPVLSVIVFDDV--DEAVRIANDT-EYGLAAAVWTSNLTTAHDVS 450 Query: 506 EKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTD-DKAGGPNILSRFVSIRNT 558 +L+ AG ++N G ++ FGG + SG DK+ + L ++ +++T Sbjct: 451 RRLR--AGTVWVNCYDEGGDMNFP-FGGYKQSGNGRDKS--LHALEKYTELKST 499 >1UXV-A nrPDB Length = 501 Score = 92.4 bits (228), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 110/435 (25%), Positives = 183/435 (42%), Gaps = 50/435 (11%) Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATML---GQGKNVYQAEIDCITELSDFFRYYV 174 ++P +R A+ KAAD+I D+ A ++ G+ K+ E+ + + Sbjct: 73 DMPGTERLAVLRKAADIIERNL--DVFAEVLVMNAGKPKSAAVGEVKAAVDRLRLAELDL 130 Query: 175 KYASDLYAQQPVESADGTWNKAEYRPLE-----GFVYAVSPFNFTAI-AANLIGAPALMG 228 K Y D T++ E L G V A++PFN+ A N I + G Sbjct: 131 KKIGGDYI-----PGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYG 185 Query: 229 NTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGS 288 N VV KPS + L + + L +AG P I + P + ++++AD A+ FTGS Sbjct: 186 NAVVVKPSISDPLPAAMAVKALLDAGFPPDAIALL-NLPGKEAEKIVADDRVAAVSFTGS 244 Query: 289 TNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQG 348 T V + + V G + Y + E GG + +V A++ A RG + + G Sbjct: 245 TEVGERV-------VKVGGVKQY---VMELGGGDPAIVLEDADLDLAADKIARGIYSYAG 294 Query: 349 QKCSAASRLYLPESKSEEFLSDMFGILQSQNVV-PMNTSASPISGGNLRGFMGPVIHEQS 407 Q+C A + + + ++ L S V P + + +GP+I + Sbjct: 295 QRCDAIKLVLAERPVYGKLVEEVAKRLSSLRVGDPRDPTVD----------VGPLISPSA 344 Query: 408 FDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKA---KRPDHPYMSTEFFGPIL 464 D+++ IEDA + +L GG+ + +V PT+++A + D E F P+ Sbjct: 345 VDEMMAAIEDAVEKGG-RVLAGGR--RLGPTYVQPTLVEAPADRVKDMVLYKREVFAPVA 401 Query: 465 TVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGA 524 E D ++ ++ N Y L A+F +D I A L+ G YIND Sbjct: 402 LAVEVKD--LDQAIELA-NGRPYGLDAAVFGRDVVKIRRAVRLLEV--GAIYINDMPRHG 456 Query: 525 VVSQQWFGGARMSGT 539 + FGG + SG Sbjct: 457 -IGYYPFGGRKKSGV 470 >3B4W-A nrPDB Length = 495 Score = 92.0 bits (227), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 107/445 (24%), Positives = 196/445 (44%), Gaps = 44/445 (9%) Query: 116 WYNLPFYDRSAIFLKAADLIST-KYRYDMLAATMLGQGKNVYQAEIDCITELSDF--FRY 172 W + P ++R+A+ A +++ K + L A GQ + I+ + + Y Sbjct: 64 WPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPPTI----IETMHWMGSMGAMNY 119 Query: 173 YVKYASDLYAQQPVESADGTWNKAEY-RPLEGFVYAVSPFNFTA-IAANLIGAPALMGNT 230 + A + E+ G++ ++ R G V A+ +N +A N I L G T Sbjct: 120 FAGAADKVTW---TETRTGSYGQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCT 176 Query: 231 VVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTN 290 +V KP+ L+ L V E GLP+GV++ +PG ++ + ++ D FTGS+ Sbjct: 177 IVLKPAAETPLTANALAEVFAEVGLPEGVLSVVPGG-IETGQALTSNPDIDMFTFTGSSA 235 Query: 291 VFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQK 350 V + + G+ + +++ P + E GGK+ ++ +++ A+ + GQ Sbjct: 236 VGREV-GRRAAEMLK------PCTL-ELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQG 287 Query: 351 CSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDK 410 C +R+ P S+ +E ++ + + + V P + A+ I GP+I E+ + Sbjct: 288 CVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQI---------GPLISEKQRTR 338 Query: 411 LVKVIEDAKKDPELEILYGGQYDK-SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEY 469 + I ++ + GG+ + G+F+ PTV E FGP+L + Y Sbjct: 339 VEGYIAKGIEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKMTIAQEEIFGPVLAIIPY 398 Query: 470 PDTEFNEICDIIDNTSQYALTGAIFAKD-RKAIEYADEKLKFSAG-NFYINDKCTGAVVS 527 DTE + I I N S Y L G+++ D K I+ + + + G N+Y D + Sbjct: 399 -DTEEDAIA--IANDSVYGLAGSVWTTDVPKGIKISQQIRTGTYGINWYAFDPGSP---- 451 Query: 528 QQWFGGARMSGTDDKAGGPNILSRF 552 FGG + SG + GP + F Sbjct: 452 ---FGGYKNSGI-GRENGPEGVEHF 472 >4H7N-A nrPDB Length = 474 Score = 91.7 bits (226), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 100/356 (28%), Positives = 150/356 (42%), Gaps = 36/356 (10%) Query: 204 FVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINF 262 V +SP+NF + + PAL+ G VV KPS+ A L+ L + V+ F Sbjct: 129 LVGVISPWNFPLTLSMIDTIPALLAGCAVVVKPSEIAPRFVAPLLMALNTVPELRDVLIF 188 Query: 263 IPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKN 322 + G + ++ DF + FTGS + V E R + E GGK+ Sbjct: 189 VEGGG-ETGANLINYVDF--VCFTGSVATGRE--------VAETAARRFIPAYLELGGKD 237 Query: 323 FHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVP 382 +V SAN+ A + + G GQ C + R+Y+ ESK EEF + + Sbjct: 238 PAIVLESANLELATSAILWGAVVNTGQSCLSIERIYVAESKFEEFYHQLIAKAHRLQL-- 295 Query: 383 MNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDK-SQGWFVG 441 A P+ G +GP+I E+ + I DA + + I GG+ ++ GW+ Sbjct: 296 ----AYPLVED---GAIGPIIAEKQAGIINDHILDAVEKGAV-IHCGGKVEELGGGWWCR 347 Query: 442 PTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAI 501 PTV+ M+ E FGPI+ V +PD E + N + Y L+ A+FA Sbjct: 348 PTVMTNVNHSMKVMTEETFGPIMPVMPFPDVEE---AVYLANDTIYGLSAAVFAGSE--- 401 Query: 502 EYADEKLK----FSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFV 553 DE LK +AG IND A++ + SG G L RF+ Sbjct: 402 ---DEALKVARQLNAGAISINDAALTAMMHEGEKNAFNFSGLGGSRVGAAGLKRFL 454 >5VBF-A nrPDB Length = 478 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 125/489 (25%), Positives = 199/489 (40%), Gaps = 43/489 (8%) Query: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFY 122 L I+G R +D + R P +P +VL + AT D+ AV+AA A W + Sbjct: 9 LYIDG-RFHDADGRRTQPVVDPGT-TRVLGELPHATAHDIDAAVQAAHRAFVTWRHESPL 66 Query: 123 DRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYA 182 RS + +AA L + TM QGK + +A I + ++ ++ + Y Sbjct: 67 VRSDLLRRAAALARERAETIGRHITM-DQGKPLREA-IAEVVSAAEQLEWHAEEGRRTYG 124 Query: 183 QQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFT-AIAANLIGAPALMGNTVVWKPSQTAA 240 + P S D P+ G A SP+NF + A + I A G T+V K + + Sbjct: 125 RVVPARSPD-VMQTVLREPI-GVCAAFSPWNFPFSQAMHKIAAALASGCTLVLKGPEESP 182 Query: 241 LSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQ 300 + L + +AGLP G +N + G P V+ Q++ + FTGS V K L Sbjct: 183 SAIVALAQLFHDAGLPPGCLNIVWGVPGDVSKQLIEAPQVRKISFTGSVPVGKQLAALAA 242 Query: 301 SGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLP 360 S + R+ E GG LV A++ A F GQ C + +R ++ Sbjct: 243 SLM--------KRMTMELGGHAPVLVCADADVERAAAMLAAYKFRNAGQVCVSPTRFFVQ 294 Query: 361 ESKSEEFLS---DMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 + + F+ D G ++ + + MGP+ H + D++ + D Sbjct: 295 RAAFDRFVCAYLDAVGTIRVGYGLDAGVT------------MGPLAHARRVDEIDAFVAD 342 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE--FN 475 A +I GG G + PTV+ D M+ E FGPI+ + + D + Sbjct: 343 ATAK-GAQIATGGMRLPGPGHYFAPTVVLGPTRDTRLMNDEPFGPIVGIVPFDDLDDALA 401 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 E + + YA T + A++ I A E AG IN G ++ FGG + Sbjct: 402 EANRLPFGLASYAFTTS--ARNAHRISRALE-----AGMVNINHFGMGP--AEIPFGGVK 452 Query: 536 MSGTDDKAG 544 SG + G Sbjct: 453 DSGFGSEGG 461 >3EFV-A nrPDB Length = 462 Score = 89.0 bits (219), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 109/462 (23%), Positives = 193/462 (41%), Gaps = 40/462 (8%) Query: 82 TNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRY 141 NPA Q LA + A +++ +A+ A K W R+ + + Sbjct: 12 VNPATGQ-TLAAMPWANAQEIEHALSLAASGFKKWKMTSVAQRAQTLRDIGQALRA-HAE 69 Query: 142 DMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQP--VESADGTWNKAEYR 199 +M GK + QA + +T+ + +Y ++ + +P VE+ EYR Sbjct: 70 EMAQCITREMGKPIKQARAE-VTKSAALCDWYAEHGPAMLNPEPTLVENQQAV---IEYR 125 Query: 200 PLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKG 258 PL G + A+ P+NF P L+ GN+ + K + ++ +L EAG P G Sbjct: 126 PL-GVILAIMPWNFPLWQVLRGAVPILLAGNSYLLKHAPNVTGCAQMIARILAEAGTPAG 184 Query: 259 VINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGET 318 V ++ + V+ Q++ D A+ TGS + + + + + E Sbjct: 185 VYGWVNANNEGVS-QMINDPRIAAVTVTGSV--------RAGAAIGAQAGAALKKCVLEL 235 Query: 319 GGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQ 378 GG + +V A++ AV + + G ++ GQ C+AA R + E ++ F +D F + + Sbjct: 236 GGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFIVEEGIAQAF-TDRF--VAAA 292 Query: 379 NVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGW 438 + M P+ N +GP+ D+L + ++ + + +L GG+ +G Sbjct: 293 AALKMG---DPLVEEN---DLGPMARFDLRDELHQQVQASVAEGA-RLLLGGEKIAGEGN 345 Query: 439 FVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIF-AKD 497 + TV+ PD E FGP+ + D + N S++ L+ IF A D Sbjct: 346 YYAATVLADVTPDMTAFRQELFGPVAAITVAKDAAH---ALALANDSEFGLSATIFTADD 402 Query: 498 RKAIEYADEKLKFSAGNFYIND-KCTGAVVSQQWFGGARMSG 538 A E A + G +IN + A V+ FGG + SG Sbjct: 403 TLAAEMAA---RLECGGVFINGYSASDARVA---FGGVKKSG 438 >4OGD-A nrPDB Length = 465 Score = 88.2 bits (217), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 109/472 (23%), Positives = 199/472 (42%), Gaps = 51/472 (10%) Query: 76 RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLP-FYDRSAIFLKAADL 134 + ++P TN +VL T++ + + ++ A K W +R A + A++ Sbjct: 4 QTIYPYTN-----EVLHTFDNMTDQGLADVLERAHLLYKKWRKEDHLEERKAQLHQVANI 58 Query: 135 IST-KYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTW 193 + + +Y + +G+ Q E+D +++D YY A + P+E+ G Sbjct: 59 LRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIAD---YYADKADEFLMSTPLETDSG-- 113 Query: 194 NKAEY-RPLEGFVYAVSPFNFTAIAANLIGAPA-LMGNTVVWKPSQTAALSNYLLMTVLE 251 +A Y + G + AV P+NF + AP ++GN +V K + S ++ Sbjct: 114 -QAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVL 172 Query: 252 EAGLPKGVIN--FIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYR 309 EAG G I FI D V QV+ADK + TGS + + + E + Sbjct: 173 EAGAEAGSITNLFISYDQVS---QVIADKRVVGVCLTGSE--------RGGASIAEEAGK 221 Query: 310 DYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPE---SKSEE 366 + + E GG + ++ A+ GQ C+++ R + + + +E Sbjct: 222 NLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKE 281 Query: 367 FLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEI 426 L+ +F + + + T+ +P+S + D++ + D E+ Sbjct: 282 LLTKVFKTAKWGDPMDPETTLAPLSSAQAKA--------DVLDQIKLAL-----DHGAEL 328 Query: 427 LYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQ 486 +YGG+ G FV PT+I D+P E FGP+ +Y+ E E ++ N S Sbjct: 329 VYGGEAIDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEE--EAIEVA-NDSN 385 Query: 487 YALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 Y L G IF+ +++ + K++ G +IN T + + FGG + SG Sbjct: 386 YGLGGTIFSSNQEHAKAVAAKIE--TGMSFINSGWTS--LPELPFGGIKHSG 433 >5N5S-A nrPDB Length = 515 Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 129/466 (27%), Positives = 203/466 (43%), Gaps = 60/466 (12%) Query: 90 VLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM- 148 V A V QAT KD+ +A+ AA A + Y+R A+ K + K R++ +A T+ Sbjct: 66 VAAKVPQATHKDIDDAIDAAVAAAPAMAAMGAYERKAVLEKV--VAELKNRFEEIAQTLT 123 Query: 149 LGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQ-PVESA---DGTWNKAEYRPLEGF 204 + GK + A + +T D F+ + + +Y + P++ + G + P+ G Sbjct: 124 MESGKPIKDARGE-VTRTIDTFQVAAEESVRIYGEHIPLDISARNKGLQGIVKKFPI-GP 181 Query: 205 VYAVSPFNFTAIAANLIG---APAL-MGNTVVWKPSQTAALSNYLLMTVLEE-AGLPKGV 259 V VSP+NF NL+ APA+ +G V KP+ LS +L +L + LP G Sbjct: 182 VSMVSPWNF---PLNLVAHKVAPAIAVGCPFVLKPASRTPLSALILGEILHKIEELPLGA 238 Query: 260 INFIPGDPVQVTDQVLADKDFGALHFTGSTNV---FKSLYGKIQSGVVEGKYRDYPRIIG 316 + +P + D D+ F L FTGS + K+ GK +++ Sbjct: 239 FSILPVSR-EDADMFTVDERFKLLTFTGSGPIGWDMKARAGK-------------KKVVM 284 Query: 317 ETGGKNFHLVHPSA-NISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGIL 375 E GG +V ++ + + I G F GQ C RLY+ E +E + Sbjct: 285 ELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYVHERLYDEVKEGFVAAV 344 Query: 376 QSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPEL---EILYGGQY 432 + + +P ++GP+I E + K IED K+ ++L GG Sbjct: 345 KKLKM------GNPFEEDT---YLGPMISESA----AKGIEDWVKEAVAKGGKLLTGGN- 390 Query: 433 DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGA 492 +G F+ PTVI+ + E FGP++ +Y+Y D F E +NT Y L Sbjct: 391 --RKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSD--FKEAVKECNNT-HYGLQSG 445 Query: 493 IFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 IF KD YA E ++ G +ND V SQ +GG + SG Sbjct: 446 IFTKDLNKAFYAFEHME--VGGVILNDSPALRVDSQP-YGGLKDSG 488 >4YWE-A nrPDB Length = 487 Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 88/381 (23%), Positives = 152/381 (39%), Gaps = 33/381 (8%) Query: 169 FFRYYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNF-TAIAANLIGAPAL 226 +F +Y A L+ + P ++ + R G + P+N+ I +GA Sbjct: 117 YFEFYAGAADKLHGETLPYQAG---YTVLTVREPHGVTGHIVPWNYPMQIFGRSVGAALA 173 Query: 227 MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFT 286 GN V KP++ A LS + + EAGLP G +N + G + + + FT Sbjct: 174 AGNACVVKPAEDACLSVLRVAELAAEAGLPAGALNIVTGYGHEAGAALARHPGIDHISFT 233 Query: 287 GSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF 346 GS GK+ V + ++ + E GGK+ +V A++ A+ + + Sbjct: 234 GSPAT-----GKL---VTQMAAENHVPVTLELGGKSPQIVFADADLDAALPVLVSAIVQN 285 Query: 347 QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQ 406 GQ CSA SR+ + + E + + V P GP+I+ + Sbjct: 286 GGQTCSAGSRVLIERAVYEPLVERLATAFNGLRVGPSRADLD----------CGPLINAK 335 Query: 407 SFDKLVKVIEDAKKDPELEILYGGQY---DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI 463 ++ + DA+ D + + GQ G++ P +++ P H E FGP+ Sbjct: 336 QQQRVWDFLSDAQHD-GIPMAAHGQVVADAPESGFYQAPALLRDVPPSHRLAQEEVFGPV 394 Query: 464 LTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTG 523 L + D + + N + Y L I+ +D +L+ AG +IN+ G Sbjct: 395 LAAMRFVD---EDEAVALANGTPYGLVAGIWTRDGARQMRLARRLR--AGQVFINNYGAG 449 Query: 524 AVVSQQWFGGARMSGTDDKAG 544 V + FGG SG + G Sbjct: 450 GGV-ELPFGGVGHSGHGREKG 469 >4I3V-A nrPDB Length = 488 Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 82/365 (22%), Positives = 155/365 (42%), Gaps = 48/365 (13%) Query: 205 VYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFI 263 + A++PFN APA+ N VV KP++ ++ LL +L EAGLP +++ + Sbjct: 154 ISAITPFNHPLNMVAHKVAPAIATNNCVVVKPTELTPMTALLLADILYEAGLPPEMLSVV 213 Query: 264 PGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNF 323 G P + +++ + + FTGS V K + Y R + E GG + Sbjct: 214 TGWPADIGMEMITNPHVDLVTFTGSVPVGKLIAANAH----------YKRQVLELGGNDP 263 Query: 324 HLV---HPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNV 380 ++ +++ A + G + GQ+C+A R+ ES ++ F+ +L+ Sbjct: 264 LIILNDLSDDDLARAADLAVAGATKNSGQRCTAVKRILCQESVADRFVP---LVLERAKR 320 Query: 381 V----PMNTSASPISGGNLRGFMGPVIHEQSF----DKLVKVIEDAKKDPELEILYGGQY 432 + PM+ S +G VIHE++ +++++ E+ +ILY + Sbjct: 321 LRFGDPMDRSTD----------LGTVIHEKAAALFEERVMRAAEEGA-----DILY---H 362 Query: 433 DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGA 492 G + P V+ + E FGPI+ + PD + I + N++ + L+ Sbjct: 363 PGRSGALLPPIVVDRVPHQSDLVLEETFGPIIPIVRVPDDDDATIT--LSNSTAFGLSSG 420 Query: 493 IFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRF 552 + D + ++ LK N + + G + FGG + SG K G + F Sbjct: 421 VCTNDYRRMQKYIAGLKVGTVNIW---EVPGYRIEMSPFGGIKDSGNGYKEGVIEAMKSF 477 Query: 553 VSIRN 557 +++ Sbjct: 478 TNVKT 482 >3VZ3-A nrPDB Length = 457 Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 96/378 (25%), Positives = 156/378 (41%), Gaps = 30/378 (7%) Query: 98 TEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLIST-KYRYDMLAATMLGQGKNVY 156 T ++ + A++A + + F R AA ++ ++ + T +G+ + Sbjct: 24 TPAEIDAKLAKAQEAFQAYRRTSFSQRRQWLENAAAILERDTSKFAEIMTTEMGK---TH 80 Query: 157 QAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAI 216 Q+ I + + RYY ++ A + E+ T + Y+PL G + AV P+NF Sbjct: 81 QSAIAEAEKSALVCRYYAEHGEQFLANEYTET-QATESYVCYQPL-GILLAVMPWNFPFW 138 Query: 217 AANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVL 275 APALM GN V K + + +LE AG P+GV + QV +QV+ Sbjct: 139 QVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEAAGFPEGVFQTLLIGASQV-EQVI 197 Query: 276 ADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHA 335 D A TGS SL + P ++ E GG + +V PSA++ A Sbjct: 198 KDPRVKAATLTGSEPAGASLASLAGQEI-------KPTLL-ELGGSDPFVVFPSADLDEA 249 Query: 336 V-LSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV-PMNTSASPISGG 393 V + T+ T GQ AA R L E+ + EFL + S + PM Sbjct: 250 VEVGTVARTMN-NGQSAIAAKRFILHEAIAAEFLEKLHLKFASLKIGDPMAPETD----- 303 Query: 394 NLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHP 453 +GP+ E + + ++ A +IL GG+ G+F PT++ P Sbjct: 304 -----IGPLATEGILQDISRQVDQAVAAGA-KILLGGRPLDRAGYFYPPTILTEIPPGAK 357 Query: 454 YMSTEFFGPILTVYEYPD 471 + E F P+ V+ D Sbjct: 358 ILQEELFAPVAMVFTVKD 375 >5UCD-A nrPDB Length = 457 Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 116/452 (25%), Positives = 191/452 (42%), Gaps = 50/452 (11%) Query: 101 DVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQ-AE 159 D + + + A A + ++ F +S LK A + + + Y LA LG+ K+V AE Sbjct: 31 DSLFSAQKAYFATRATADVGFRKQSLERLKEAVINNKEALYSALAED-LGKPKDVVDLAE 89 Query: 160 IDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLE--GFVYAVSPFNFTA-- 215 I + DF + + + A V S D Y E G Y + PFN+ Sbjct: 90 IGAVLHEIDF---ALAHLDEWVAPVSVPSPDIIAPSECYVVQEPYGVTYIIGPFNYPVNL 146 Query: 216 IAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVL 275 LIGA + GNT + KPS+T ++ ++ ++ EA P+ V G + + L Sbjct: 147 TLTPLIGA-IIGGNTCIIKPSETTPETSAVIEKIIAEAFAPEYVAVIQGG---RDENSHL 202 Query: 276 ADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHA 335 F + FTGS NV GK+ V++ + ++ E GGK +V P A++ Sbjct: 203 LSLPFDFIFFTGSPNV-----GKV---VMQAAAKHLTPVVLELGGKCPLIVLPDADLDQT 254 Query: 336 VLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNL 395 V + G F GQ A LY+ S + L + ++++ +P S Sbjct: 255 VNQLMFGKFINSGQTXIAPDYLYVHYSVKDALLERLVERVKTE--LPEINST-------- 304 Query: 396 RGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYM 455 G ++ E+ +LV ++E + ++L G Q D S+ TV+ + P M Sbjct: 305 ----GKLVTERQVQRLVSLLEATQG----QVLVGSQADVSKRAL-SATVVDGVEWNDPLM 355 Query: 456 STEFFGPILTVYEYPDTEFNEICDIIDNTSQY---ALTGAIFAKDRKAIEYADEKLKFSA 512 S E FGPIL P EF+ + ID +++ L +F KD + +++ + Sbjct: 356 SEELFGPIL-----PVLEFDSVRTAIDQVNKHHPKPLAVYVFGKDMDVAKGIINQIQ--S 408 Query: 513 GNFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544 G+ +N A FGG SG + G Sbjct: 409 GDAQVNGVMLHAFSPYLPFGGIGASGMGEYHG 440 >2W8P-A nrPDB Length = 487 Score = 79.0 bits (193), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 103/427 (24%), Positives = 179/427 (41%), Gaps = 31/427 (7%) Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W + +RS++ K +L+ + + D+ GK + +A + I + F ++ + Sbjct: 64 WREVSAKERSSLLRKWYNLM-IQNKDDLARIITAESGKPLKEAHGE-ILYSAFFLEWFSE 121 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNF-TAIAANLIGAPALMGNTVVWK 234 A +Y A +P+ G ++P+NF +A+ +GA G TVV K Sbjct: 122 EARRVYGDIIHTPAKDRRALVLKQPI-GVAAVITPWNFPSAMITRKVGAALAAGCTVVVK 180 Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPG---DPVQVTDQVLADKDFGALHFTGSTNV 291 P++ S L + +AG+P GV N IP + +V + + D + FTGST Sbjct: 181 PAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTT 240 Query: 292 FKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKC 351 K L + V R+ E GG +V SAN+ AV + F GQ Sbjct: 241 GKILLHHAANSV--------KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTA 292 Query: 352 SAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKL 411 +++ + + F+ F +N+ N + GP+I+E++ +K+ Sbjct: 293 VCSNQFLVQRGIHDAFV-KAFAEAMKKNLRVGNGFEEGTT-------QGPLINEKAVEKV 344 Query: 412 VKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPD 471 K + DA ++ GG+ + F PT++ D E FGP+ V ++ D Sbjct: 345 EKQVNDAVSKGA-TVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKF-D 402 Query: 472 TEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWF 531 TE I N + L G +++D I E+L+ G +N+ +V + F Sbjct: 403 TEEEA--IAIANAADVGLAGYFYSQDPAQIWRVAEQLEV--GMVGVNEGLISSV--ECPF 456 Query: 532 GGARMSG 538 GG + SG Sbjct: 457 GGVKQSG 463 >3ROS-A nrPDB Length = 484 Score = 78.6 bits (192), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 120/510 (23%), Positives = 211/510 (41%), Gaps = 71/510 (13%) Query: 76 RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLI 135 +++ P TN A A+ T K + A+ A K W + R+ I A+ + Sbjct: 7 QSVNPYTNEA-----FASYDNPTSKQIDEAINLAHALYKKWRHEEPASRAEILHDIANAL 61 Query: 136 STKYRYDMLAATM-LGQGKNVYQAEID---CITELSDFFRYYVKYASDLYAQQPVESADG 191 K D LA M L GK + +++ + C++ YY + ++ +P + Sbjct: 62 --KEHEDELAKMMTLEMGKLLSESKEEVELCVS----ICNYYADHGPEML--KPTKLNSD 113 Query: 192 TWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPA-LMGNTVVWKPSQTAALSNYLLMTVL 250 N + G + A P+NF + AP ++GN ++ K + S L ++ Sbjct: 114 LGNAYYLKQSTGVIMACEPWNFPLYQVIRVFAPNFIVGNPILLKHAHNVPGSAALTAKII 173 Query: 251 EEAGLPKG-VINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYR 309 + AG P+G +IN P Q+ D ++AD + TGS + S V E + Sbjct: 174 KRAGAPEGSLINLYPSYD-QLAD-IIADPRIQGVALTGSE--------RGGSAVAEAAGK 223 Query: 310 DYPRIIGETGGKNFHLVHPSAN--ISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEF 367 + + E GG + +V A+ + VL+ R T+ GQ C+++ R+ + +S+ +E Sbjct: 224 NLKKSTMELGGNDAFIVLDDADPQVLRNVLNDAR-TYN-DGQVCTSSKRIIVEKSRYDEV 281 Query: 368 LSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEIL 427 L ++ +NV + P+ + P+ E++ +KL +++A D ++ Sbjct: 282 LHEL------KNVFSNLKAGDPLEADTT---LPPMNSEKAKEKLEAQVKEAI-DAGAKVF 331 Query: 428 YGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQY 487 Y S+G F PT++ D+P E FGPI V+ D + + N S Y Sbjct: 332 YQYPEIDSKGAFFRPTILTDIAKDNPVFDKEVFGPIAEVFVVED---DNAAIQLANDSSY 388 Query: 488 ALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW-------FGGARMSGTD 540 L ++ D D K SA I T V++ +W FGG + SG Sbjct: 389 GLGSSVIGSD------IDRAKKVSA---QIETGMT--VINGRWITSGELPFGGIKKSGYG 437 Query: 541 DKAGGPNILSRF-------VSIRNTKENFY 563 + G +++ V+ N EN Y Sbjct: 438 RELSGLGLMAFVNEHLVIDVTKNNQAENLY 467 >3SZA-A nrPDB Length = 469 Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 112/452 (24%), Positives = 179/452 (39%), Gaps = 49/452 (10%) Query: 102 VMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEID 161 + AVK A+ A P R L+A + + +++ A KN + A + Sbjct: 20 ISEAVKRARAAFSSGRTRPLQFRIQ-QLEALQRLIQEQEQELVGALAADLHKNEWNAYYE 78 Query: 162 CITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEY---RPLEGFVYAVS----PFNFT 214 + + + Y ++ + A +PVE T Y PL G V + PFN T Sbjct: 79 EVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPL-GVVLVIGTWNYPFNLT 137 Query: 215 AIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQV 274 ++GA A GN VV KPS+ + LL T++ + L K + I G + T+ Sbjct: 138 I--QPMVGAIA-AGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTE-- 191 Query: 275 LADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISH 334 L + F + +TGST V GKI ++ + + E GGK+ V + ++ Sbjct: 192 LLKERFDHILYTGSTGV-----GKI---IMTAAAKHLTPVTLELGGKSPCYVDKNCDLDV 243 Query: 335 AVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGN 394 A G F GQ C A + S +Q+Q V + S G + Sbjct: 244 ACRRIAWGKFMNSGQTCVAPDYILCDPS------------IQNQIVEKLKKSLKEFYGED 291 Query: 395 LRGFM--GPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDH 452 + G +I + F +++ +IE K + YGG D + ++ PT++ P Sbjct: 292 AKKSRDYGRIISARHFQRVMGLIEGQK------VAYGGTGDAAT-RYIAPTILTDVDPQS 344 Query: 453 PYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSA 512 P M E FGP+L + E E I N + L +F+ + K I+ + S+ Sbjct: 345 PVMQEEIFGPVLPIVCVRSLE--EAIQFI-NQREKPLALYMFSSNDKVIKKMIAET--SS 399 Query: 513 GNFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544 G ND + FGG SG G Sbjct: 400 GGVAANDVIVHITLHSLPFGGVGNSGMGSYHG 431 >5JRY-A nrPDB Length = 485 Score = 73.9 bits (180), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 115/439 (26%), Positives = 174/439 (39%), Gaps = 42/439 (9%) Query: 108 AAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLA-ATMLGQGKNVYQAEIDCITEL 166 AA DA K LP Y R A+ + + R+D LA A + GK + A+ + +T L Sbjct: 57 AAVDATKPMRELPAYKRQAVLDHC--VARFRERFDELAEALCIEAGKPINDAKGE-VTRL 113 Query: 167 SDFFRYY----VKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIG 222 D FR V+ ++ + A G P+ G +SPFNF A Sbjct: 114 IDTFRVASEEAVRIDGEVLNLEISARAQGYTGYTRRVPI-GPCSFISPFNFPLNLAAHKV 172 Query: 223 APALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFG 281 APAL G V KP+ + ++ VL E LPKG + +P D D F Sbjct: 173 APALAAGCPFVLKPASRTPVGALIIGEVLAETDLPKGAFSVLPAHR-DGADLFTTDDRFR 231 Query: 282 ALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA--NISHAVLST 339 L FTGS V +L K GK +++ E GG +V + + V Sbjct: 232 LLSFTGSPAVGWALKEK------AGK----KKVVLELGGNAAAIVDADQLDRLDYVVDRL 281 Query: 340 IRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFM 399 G F GQ C R+ L + + L D ++ + M P + F+ Sbjct: 282 AFGAFYQSGQSCIGVQRI-LAHADIYDALRDK--LIAKTRSLKMGDPKDPST------FV 332 Query: 400 GPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEF 459 GP+I E +L + DA +I+ GG+ D G T+++ D E Sbjct: 333 GPMISESESRRLSGWM-DAAVAAGAKIVAGGKVD---GAMFEATLLENVGRDQDLYRKEA 388 Query: 460 FGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYIND 519 FGPI + ++ F++ + N S + L +F + A ++L+ G IND Sbjct: 389 FGPIAILEKF--DRFDDALARV-NDSDFGLQAGVFTDSLAHTQQAWDELEV--GGVVIND 443 Query: 520 KCTGAVVSQQWFGGARMSG 538 V +GG + SG Sbjct: 444 -VPSFRVDNMPYGGVKDSG 461 >5KF0-A nrPDB Length = 485 Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 110/439 (25%), Positives = 173/439 (39%), Gaps = 42/439 (9%) Query: 108 AAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLA-ATMLGQGKNVYQAEIDCITEL 166 AA DA K LP Y R A+ + + R+D LA A + GK + + + +T L Sbjct: 57 AAVDAVKPMRELPAYRRQAVLDHC--VARFRERFDELAEALCIEAGKPINDSRGE-VTRL 113 Query: 167 SDFFRYY----VKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIG 222 D FR V+ ++ + A G P+ G +SPFNF A Sbjct: 114 IDTFRVASEEAVRIDGEVLNLEISARAQGYTGYTRRVPI-GPCSFISPFNFPLNLAAHKV 172 Query: 223 APALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFG 281 APAL G V KP+ + ++ VL E LPKG + +P D D+ F Sbjct: 173 APALAAGCPFVLKPASRTPVGALIIAEVLAETNLPKGAFSVLPAHR-DGADLFTTDERFR 231 Query: 282 ALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPS--ANISHAVLST 339 L FTGS V +L K GK +++ E GG +V + + V Sbjct: 232 LLSFTGSPAVGWALKEK------AGK----KKVVLELGGNAAAIVDADQFEQLDYVVDRL 281 Query: 340 IRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFM 399 G + GQ C R+ + S + + +S + M P + F+ Sbjct: 282 AFGAYYQSGQSCIGVQRILVHASLYDTLRDKLVAKTRS---LKMGDPKDPST------FV 332 Query: 400 GPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEF 459 GP+I E +L + DA +I+ GG+ D G T+++ + E Sbjct: 333 GPMISESESRRLSGWM-DAAVAAGAKIIAGGKVD---GAMFEATLLEDVGREQDLYRKEA 388 Query: 460 FGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYIND 519 FGP+ + ++ F++ + N S + L +F + A ++L+ G IND Sbjct: 389 FGPVAILEKF--DRFDDALARV-NDSDFGLQAGVFTDSLTHAQRAWDELEV--GGVVIND 443 Query: 520 KCTGAVVSQQWFGGARMSG 538 V +GG + SG Sbjct: 444 -VPSFRVDNMPYGGVKDSG 461 >1AD3-A nrPDB Length = 452 Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 96/396 (24%), Positives = 161/396 (40%), Gaps = 48/396 (12%) Query: 152 GKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEY---RPLEGFVYAV 208 GKN + + + + + + +K D +PV T Y PL G V + Sbjct: 52 GKNEWTSYYEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDLYIHSEPL-GVVLVI 110 Query: 209 S----PFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIP 264 PFN T ++GA A GN V+ KPS+ + LL T++ + + + + + Sbjct: 111 GAWNYPFNLTI--QPMVGAVA-AGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVK 166 Query: 265 GDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFH 324 G + T+ L + F + +TGST V GKI V+ + + E GGK+ Sbjct: 167 GGVPETTE--LLKERFDHIMYTGSTAV-----GKI---VMAAAAKHLTPVTLELGGKSPC 216 Query: 325 LVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMN 384 V ++ A G F GQ C A + S +Q+Q V + Sbjct: 217 YVDKDCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPS------------IQNQIVEKLK 264 Query: 385 TSASPISGGNLRGFM--GPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGP 442 S G + + G +I+++ F ++ +I++ K + +GG +D+S ++ P Sbjct: 265 KSLKDFYGEDAKQSRDYGRIINDRHFQRVKGLIDNQK------VAHGGTWDQS-SRYIAP 317 Query: 443 TVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIE 502 T++ P P M E FGP++ + E E I N + L +F+ + K I+ Sbjct: 318 TILVDVDPQSPVMQEEIFGPVMPIVCVRSLE--EAIQFI-NQREKPLALYVFSNNEKVIK 374 Query: 503 YADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + S+G ND V FGG SG Sbjct: 375 KMIAET--SSGGVTANDVIVHITVPTLPFGGVGNSG 408 >4QGK-A nrPDB Length = 461 Score = 65.9 bits (159), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 101/405 (24%), Positives = 168/405 (41%), Gaps = 53/405 (13%) Query: 144 LAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEY---RP 200 +AA + NVY E+ + DF ++ + +PV+ T Y +P Sbjct: 46 IAADLCKSEFNVYSQEVITVLGEIDFM---LENLPEWVTAKPVKKNVLTMLDEAYIQPQP 102 Query: 201 LEGFVYAVSPFN--FTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKG 258 L G V + +N F LIGA A GN V+ KPS+ + + +L +L + L + Sbjct: 103 L-GVVLIIGAWNYPFVLTIQPLIGAIA-AGNAVIIKPSELSENTAKILAKLLPQY-LDQD 159 Query: 259 VINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGET 318 + I G + T+ L + F + +TG+T V GKI V+E + + E Sbjct: 160 LYIVINGGVEETTE--LLKQRFDHIFYTGNTAV-----GKI---VMEAAAKHLTPVTLEL 209 Query: 319 GGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQ 378 GGK+ + ++ G + GQ C A + S LQ+Q Sbjct: 210 GGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEAS------------LQNQ 257 Query: 379 NVVPMNTSASPISGGNLRGFMGP----VIHEQSFDKLVKVIEDAKKDPELEILYGGQYDK 434 V + + G N++ P +I+ + F +++ ++E K I +GG+ D+ Sbjct: 258 IVWKIKETVKEFYGENIKE--SPDYERIINLRHFKRILSLLEGQK------IAFGGETDE 309 Query: 435 SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIF 494 + ++ PTV+ P M E FGPIL + P +E + I N + L +F Sbjct: 310 ATR-YIAPTVLTDVDPKTKVMQEEIFGPILPI--VPVKNVDEAINFI-NEREKPLALYVF 365 Query: 495 AKDRKAIE-YADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + + K I+ DE S+G ND ++ FGG SG Sbjct: 366 SHNHKLIKRMIDET---SSGGVTGNDVIMHFTLNSFPFGGVGSSG 407 >5J6B-A nrPDB Length = 485 Score = 65.5 bits (158), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 108/435 (24%), Positives = 166/435 (38%), Gaps = 42/435 (9%) Query: 112 AKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLA-ATMLGQGKNVYQAEIDCITELSDFF 170 A+K LP + R AI + + R+D LA A + GK + ++ + +T L D F Sbjct: 61 AQKPLRALPAFRRQAILEHC--VARFRERFDELAQALCIEAGKPINDSKGE-VTRLIDTF 117 Query: 171 RYY----VKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL 226 R V+ L + A G + P+ G +SPFNF A APAL Sbjct: 118 RVAAEESVRIEGGLVNLEISPRAQGYSGYYKRVPI-GPCSFISPFNFPLNLAAHKVAPAL 176 Query: 227 M-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHF 285 G V KP+ + ++ VL E LPKG + +P D D+ F L F Sbjct: 177 AAGCPFVLKPASRTPIGALIIGEVLAETDLPKGAFSILPAHR-DGADLFTTDERFKLLSF 235 Query: 286 TGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSAN--ISHAVLSTIRGT 343 TGS V L K V + E GG +V + + V G Sbjct: 236 TGSPTVGWELKKKAGKKKV----------VLELGGNAAAIVDADQREVLDYVVERLAFGA 285 Query: 344 FEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVI 403 + GQ C R+ + + +S + M P + F+GP+I Sbjct: 286 YYQSGQSCIGVQRIIAHADVYDALREKLIAKTRS---LKMGDPKDPAT------FVGPMI 336 Query: 404 HEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI 463 E +L +E A +I+ GG+ D G T+++ D E FGP+ Sbjct: 337 SESEARRLAGWME-AAVAAGAKIVAGGKVD---GAMFEATLLEGVGRDQDLYRKEAFGPV 392 Query: 464 LTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTG 523 + + D F++ + N S + L +F + A ++L+ G IND Sbjct: 393 ALLERFSD--FDDALARV-NDSDFGLQAGVFTDSLSHAQRAWDELEV--GGVVIND-VPS 446 Query: 524 AVVSQQWFGGARMSG 538 V +GG + SG Sbjct: 447 FRVDNMPYGGVKDSG 461 >2Y53-A nrPDB Length = 534 Score = 59.3 bits (142), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 82/363 (22%), Positives = 141/363 (38%), Gaps = 73/363 (20%) Query: 200 PLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKP-SQTAALSNYLLMTVLEEAGLPK 257 P G ++ FNF + APAL+ G V+ KP + TA L+ ++ V++ LP Sbjct: 150 PTRGVALFINAFNFPSWGLWEKAAPALLSGVPVIVKPATATAWLTQRMVADVVDAGILPP 209 Query: 258 GVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGE 317 G ++ I G + DQ+ + F + FTGS + +L R +P + Sbjct: 210 GALSIICGSSAGLLDQI---RSFDVVSFTGSADTAATL-------------RAHPAFVQR 253 Query: 318 TGGKNFHLVHPSANISHA------------VLSTIRGTFEFQGQKCSAASRLYLPESKSE 365 N ++ I A + +R GQKC+A R ++PE+ E Sbjct: 254 GARLNVQADSLNSAILCADATPDTPAFDLFIKEVVREMTVKSGQKCTAIRRAFVPEAALE 313 Query: 366 EFLSDMFGILQSQNVVPMNTSASPISGGNLRG---FMGPVIHEQSFDKLVKVIEDAKKDP 422 L + L + I+ GN R MG ++ + ++ ++ I +++ Sbjct: 314 PVLEALKAKL------------AKITVGNPRNDAVRMGSLVSREQYENVLAGIAALREEA 361 Query: 423 ELEILYGGQYDKSQ----------GWFVGPTVIKAKRPDHPYM--STEFFGPILTVYEYP 470 L YD S V P + PD+ + E FGP+ +V Y Sbjct: 362 VL------AYDSSAVPLIDADANIAACVAPHLFVVNDPDNATLLHDVEVFGPVASVAPYR 415 Query: 471 -DTEFNEICD----IIDNTSQYALTGAIFAKD-----RKAIEYADEKLKFSAGNFYINDK 520 T+ N + + + Q +L +I++ D R A+E AD + A + + Sbjct: 416 VTTDTNALPEAHAVALARRGQGSLVASIYSNDDAHLGRLALELADSHGRVHAISPSVQHS 475 Query: 521 CTG 523 TG Sbjct: 476 QTG 478 >6D97-A nrPDB Length = 547 Score = 55.1 bits (131), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 80/356 (22%), Positives = 147/356 (41%), Gaps = 53/356 (14%) Query: 198 YRPLEGFVYAVSPFNF--TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGL 255 YR G V ++PFNF L+GA MGN V K ++ ++ +L + GL Sbjct: 185 YRWPYGPVAIITPFNFPLEIPLLQLMGA-LYMGNKPVLKVDSKVSIVMEQMIRLLHDCGL 243 Query: 256 PKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRII 315 P ++FI D V +++L + + FTGS+ V + L ++ R+ Sbjct: 244 PAEDMDFINSDGA-VMNKLLLEANPKMTLFTGSSRVAEKLAADLKG-----------RVK 291 Query: 316 GETGGKNFHLVHPSAN-ISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGI 374 E G ++ ++ P + + + + GQKCSA S L++ ++ S L + Sbjct: 292 LEDAGFDWKILGPDVQEVDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKK 351 Query: 375 LQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDK 434 L + + T +GPV+ + + +++ + + K ++L+GG+ Sbjct: 352 LSERRKLEDLT-------------IGPVLTVTT-EAMIEHMNNLLKIRGSKVLFGGEPLA 397 Query: 435 SQGWFVGPTVIKAKRPDHPY--------------MSTEFFGPILTVYEYPDTEFNEICDI 480 + P + A +P + ++ E FGP V EY + + + + Sbjct: 398 NHSI---PKIYGAMKPTAVFVPLEEILKSGNFELVTKEIFGPFQVVTEYSEDQLELVLEA 454 Query: 481 IDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFY--INDKCTGAVVSQQWFGGA 534 + + + LT AI + D ++ D + G Y I + TGA WFG A Sbjct: 455 CERMNAH-LTAAIVSNDPLFLQ--DVLGRSVNGTTYAGIRARTTGA-PQNHWFGPA 506 >5NNO-A nrPDB Length = 546 Score = 51.6 bits (122), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 83/354 (23%), Positives = 146/354 (41%), Gaps = 39/354 (11%) Query: 197 EYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGL 255 +Y PL G V + +N+ + AL GNT V KPS+ A + LL +L + + Sbjct: 114 QYEPL-GVVLVIGTWNYPLLLILQPLLGALAAGNTAVIKPSELAPATAELLTKLLPKY-V 171 Query: 256 PKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRII 315 V+ + G V T VL ++ F + +TGS ++ V+ + + Sbjct: 172 SSDVVGIVNGG-VSETTAVLKER-FDHILYTGS--------ARVAEIVMAAAAKHLTPVT 221 Query: 316 GETGGKNFHLVHPSA--NISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFG 373 E GGK+ +V + N+ + G GQ S A + E E L D Sbjct: 222 LELGGKSPVVVDDTCADNMKVVAERIMWGKIINAGQ-TSIAPDYVVVEKSMESVLVD--A 278 Query: 374 ILQSQNVVPMNTSASPISGGNL----RGFMGP-----VIHEQSFDKLVKVIEDAKKDPEL 424 + +++ + + + G L + F+ +++ F +L++ ++ K Sbjct: 279 LAEARKAMLGDKFLKVLKGELLVKQKQQFLEESDYPRIVNASHFQRLMEFMKGGK----- 333 Query: 425 EILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNT 484 + GG+ D++ + PT++ P HP M E FGPIL V Y + + +I II N+ Sbjct: 334 -VAVGGEADEAT-LTIAPTILTNIDPTHPVMQEEIFGPILPVLTYENEK--DILKII-NS 388 Query: 485 SQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + L +F+ +++ I + + A GA FGG SG Sbjct: 389 REKPLALYVFSNNKRFIRGVESRTSSGAVVVNDVVVHAGA--DGLPFGGVGRSG 440 >5J7I-A nrPDB Length = 488 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 41/150 (27%), Positives = 69/150 (46%), Gaps = 22/150 (14%) Query: 229 NTVVWKPSQTAALSN----YLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALH 284 N +V+ P +AA ++ E AG PKG+I+ I + T++++ K + Sbjct: 159 NAIVFSPHPSAAKCTAEAARIMQEAAERAGAPKGLISCITQPTMAATNELMKHKLTDVIL 218 Query: 285 FTGSTNVFKSLY--GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRG 342 TG + K+ Y GK GV G Y +H SANI+ AV I+ Sbjct: 219 ATGGPGLVKAAYSSGKPAYGVGPGNVPVY--------------IHESANIAKAVQLIIQS 264 Query: 343 -TFEFQGQKCSAASRLYLPESKSEEFLSDM 371 TF++ G C++ L + ES E+ ++++ Sbjct: 265 KTFDY-GTICASEQALLVDESIKEKVVAEL 293 >3K9D-A nrPDB Length = 464 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 48/177 (27%), Positives = 77/177 (43%), Gaps = 25/177 (14%) Query: 201 LEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTV------LEEAG 254 + G + + +P + T I LI A GN++V+ P A +L TV E+AG Sbjct: 112 VAGLIPSTNPTS-TVIYKTLISIKA--GNSIVFSPHPNAL--KAILETVRIISEAAEKAG 166 Query: 255 LPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRI 314 PKG I+ + +Q TDQ++ KD + TG + + K+ Y SG P I Sbjct: 167 CPKGAISCMTVPTIQGTDQLMKHKDTAVILATGGSAMVKAAY---SSGT--------PAI 215 Query: 315 -IGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSD 370 +G G F + SANI AV + G C++ + + E +++ Sbjct: 216 GVGPGNGPAF--IERSANIPRAVKHILDSKTFDNGTICASEQSVVVERVNKEAVIAE 270 >5UJU-A nrPDB Length = 576 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 18/141 (12%) Query: 228 GNTVVWKPSQTA----ALSNYLLMTVLEEAGLPKGVINFI---PGDPVQVTDQVLADKDF 280 GNTV+ KP A A++ + VL EAG V+ + P D V D L + Sbjct: 232 GNTVIVKPHPGAILPLAITVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLAL-RPEI 290 Query: 281 GALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTI 340 + FTGST Q+G ++ ++ E G N ++ + ++ A + Sbjct: 291 KLIDFTGST----------QNGTWLERHAHQAQVYTEKAGVNQIVIDSTDDLKAAAKNIA 340 Query: 341 RGTFEFQGQKCSAASRLYLPE 361 + GQ C+A +Y+P Sbjct: 341 FSLALYSGQMCTAPQNIYVPR 361 >1O20-A nrPDB Length = 427 Score = 34.7 bits (78), Expect = 0.12, Method: Compositional matrix adjust. Identities = 39/159 (24%), Positives = 71/159 (44%), Gaps = 19/159 (11%) Query: 228 GNTVVWKPSQTAALSNYLLMTVLEEA----GLPKGVINFIPGDPVQVTDQVLADKDFGAL 283 GNT++ + A SN +++ + EA +P+ + FI + +++ +++ +L Sbjct: 151 GNTILLRGGSDALNSNKAIVSAIREALKETEIPESSVEFIENTDRSLVLEMIRLREYLSL 210 Query: 284 HFTGSTNVFKSLYGKIQSGVVEGKYRDYPRI-IGETGGKNFHL-VHPSANISHAVLSTIR 341 + YG I RD + + ETG N H+ V SA++ AV I Sbjct: 211 VIP------RGGYGLISF------VRDNATVPVLETGVGNCHIFVDESADLKKAVPVIIN 258 Query: 342 GTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNV 380 + G C+AA +L + E ++EFL + L+ V Sbjct: 259 AKTQRPGT-CNAAEKLLVHEKIAKEFLPVIVEELRKHGV 296 >1J39-A nrPDB Length = 351 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Query: 39 IDLKDWDLLRASLMKFKSSSLEVP-LVINGERIYDNNERALFPQTNPANHQQVLANVTQA 97 I L+ W+ + + + + +IN R Y NN L + N H VL + Sbjct: 266 ITLRVWETMASDAVMLIDEEFDTKHRIINDARFYVNNRAELIDRVNELKHSDVLRKEMLS 325 Query: 98 TEKDVMNAVKAAKDAKKD 115 + D++N +A K +D Sbjct: 326 IQHDILNKTRAKKAEWQD 343 >4D3Y-A nrPDB Length = 408 Score = 32.0 bits (71), Expect = 0.72, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%) Query: 310 DYPRIIGETGGKNFHLVHPSANISHAV------LSTIRGTFEFQGQKCSAASRLYLP 360 D + ET K +HLV N SH + +ST++ +FQG K S +S + LP Sbjct: 217 DVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMK-VMQFQGMKHSTSSPISLP 272 >4NOM-A nrPDB Length = 441 Score = 32.0 bits (71), Expect = 0.79, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%) Query: 310 DYPRIIGETGGKNFHLVHPSANISHAV------LSTIRGTFEFQGQKCSAASRLYLP 360 D + ET K +HLV N SH + +ST++ +FQG K A+S + LP Sbjct: 244 DVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMK-VMQFQGMKHRASSPISLP 299 >3MY7-A nrPDB Length = 452 Score = 32.0 bits (71), Expect = 0.80, Method: Compositional matrix adjust. Identities = 67/269 (24%), Positives = 109/269 (40%), Gaps = 32/269 (11%) Query: 94 VTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGK 153 VT E D M + K A++++ IF +AA L + + R + + G Sbjct: 3 VTNMAELDAM--IARVKKAQEEFATYSQEQVDKIF-RAASLAANQARIPLAQQAVEESGM 59 Query: 154 NVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESAD--GTWNKAE-YRPLEGFVYAVSP 210 + + ++ S+F Y KY D +E D GT AE + G V +P Sbjct: 60 GIVEDKVIKNHFASEFI--YNKY-KDEQTCGILEEDDNLGTMTIAEPVGIICGIVPTTNP 116 Query: 211 FNFTAIAANLIGAPALMGNTVVWKPSQTAALSN----YLLMTVLEEAGLPKGVINFIPGD 266 + TAI +LI N +++ P A S L++ AG PK +I +I Sbjct: 117 TS-TAIFKSLISLKTR--NGIIFSPHPRAKNSTNDAAKLVLDAAVAAGAPKDIIGWIDQP 173 Query: 267 PVQVTDQVLADKDFGALHFTGSTNVFKSLY--GKIQSGVVEGKYRDYPRIIGETGGKNFH 324 V++++ ++ D + TG + K+ Y GK GV G + P +I ET Sbjct: 174 SVELSNALMKHDDIALILATGGPGMVKAAYSSGKPAIGVGAG---NVPVVIDET------ 224 Query: 325 LVHPSANISHAVLSTIRGTFEFQGQKCSA 353 A+I AV S + G C++ Sbjct: 225 -----ADIKRAVASVLMSKTFDNGVVCAS 248 >4FGU-A nrPDB Length = 429 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 7/57 (12%) Query: 310 DYPRIIGETGGKNFHLVHPSANISHAV------LSTIRGTFEFQGQKCSAASRLYLP 360 D + ET K +HLV N SH + +ST++ +FQG K A+S + LP Sbjct: 230 DVEDLTKETLHKQYHLVKSHTNTSHVMQYGQKTISTMK-VMQFQGMKRKASSPVPLP 285 >4USR-A nrPDB Length = 361 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 159 EIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEG 203 +D +T L D +R V+ + + V SA GTW+K P EG Sbjct: 103 RVDTVTRLDDLWR--VQAGDQQWLARAVISATGTWSKPFIPPYEG 145 >5YKB-A nrPDB Length = 571 Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust. Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 12/82 (14%) Query: 438 WFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII---DNTSQYALTGAIF 494 W +G V DHP+ GP L PD NE D D +YA T IF Sbjct: 99 WVIGDLVTNHTSSDHPWFQAARRGPTL-----PDGSPNEYHDYYVWSDEGKEYADTRIIF 153 Query: 495 AKDRKAIEYADEKLKFSAGNFY 516 E ++ L AG +Y Sbjct: 154 TD----TEVSNWTLDEQAGKYY 171 >5L9W-B nrPDB Length = 732 Score = 28.5 bits (62), Expect = 9.1, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 13/62 (20%) Query: 415 IEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEF 474 ++DA EL++LYGGQ + KR P + L VY+ +TEF Sbjct: 557 VDDASFGLELDMLYGGQ-------------VNLKRMSSPLLHIRTAEDALKVYQAFETEF 603 Query: 475 NE 476 +E Sbjct: 604 SE 605 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4OE4-A nrPDB 728 0.0 5AC2-A nrPDB 551 e-157 5AC0-A nrPDB 546 e-155 4X2Q-A nrPDB 543 e-155 4LGZ-A nrPDB 543 e-154 3V9H-A nrPDB 541 e-154 5L13-A nrPDB 537 e-153 5FHZ-A nrPDB 536 e-152 1AG8-A nrPDB 531 e-151 5GT6-A nrPDB 528 e-150 1O9J-A nrPDB 524 e-149 3QAN-A nrPDB 524 e-149 3RJL-A nrPDB 516 e-146 4V3F-A nrPDB 512 e-145 5UR2-A nrPDB 508 e-144 4CAZ-A nrPDB 504 e-143 4PZ2-A nrPDB 500 e-142 4O6R-A nrPDB 497 e-141 4PXL-B nrPDB 497 e-141 4QYJ-A nrPDB 492 e-139 3IWK-A nrPDB 488 e-138 3IWJ-A nrPDB 488 e-138 4MPY-A nrPDB 487 e-138 1BPW-A nrPDB 484 e-137 3RHO-A nrPDB 483 e-137 3JZ4-A nrPDB 482 e-136 3R31-A nrPDB 477 e-135 4IDS-A nrPDB 476 e-134 6QAO-A nrPDB 473 e-134 4I8P-A nrPDB 471 e-133 4I8Q-A nrPDB 470 e-133 4GO4-A nrPDB 468 e-132 1WNB-A nrPDB 464 e-131 4O5H-A nrPDB 462 e-130 2D4E-A nrPDB 461 e-130 6C43-A nrPDB 460 e-130 6B4R-B nrPDB 458 e-129 4F3X-A nrPDB 457 e-129 5J77-A nrPDB 457 e-129 2J5N-A nrPDB 456 e-128 5IUV-A nrPDB 451 e-127 4V6H-A nrPDB 450 e-126 5KLK-A nrPDB 449 e-126 2HG2-A nrPDB 448 e-126 3I44-A nrPDB 439 e-123 3EK1-A nrPDB 437 e-123 3TY7-A nrPDB 432 e-121 6FK3-A nrPDB 429 e-120 4U3W-A nrPDB 428 e-120 3U4J-A nrPDB 425 e-119 1T90-A nrPDB 424 e-119 5TJR-A nrPDB 422 e-118 5EUY-A nrPDB 421 e-118 4ZZ7-A nrPDB 419 e-117 5X5U-A nrPDB 417 e-117 2JG7-A nrPDB 417 e-117 4LIH-A nrPDB 414 e-116 3RH9-A nrPDB 412 e-115 5VBF-A nrPDB 410 e-115 4JZ6-A nrPDB 410 e-114 3R64-A nrPDB 407 e-114 4X0T-A nrPDB 406 e-113 3K2W-A nrPDB 406 e-113 2W8P-A nrPDB 402 e-112 4DNG-A nrPDB 400 e-112 3RHD-A nrPDB 398 e-111 4PXN-A nrPDB 397 e-111 2QE0-A nrPDB 393 e-110 4YWE-A nrPDB 392 e-109 3B4W-A nrPDB 391 e-109 3PRL-A nrPDB 390 e-108 6MVR-A nrPDB 385 e-107 3ROS-A nrPDB 375 e-104 3VZ0-A nrPDB 373 e-104 5U0M-A nrPDB 373 e-103 3EFV-A nrPDB 370 e-102 5KF0-A nrPDB 367 e-101 4E4G-A nrPDB 366 e-101 3VZ3-A nrPDB 365 e-101 4OGD-A nrPDB 361 e-100 5JRY-A nrPDB 360 1e-99 3JU8-A nrPDB 359 2e-99 4KNA-A nrPDB 357 8e-99 6DBB-A nrPDB 356 1e-98 5N5S-A nrPDB 356 2e-98 5J6B-A nrPDB 353 1e-97 3SZA-A nrPDB 350 1e-96 1AD3-A nrPDB 330 1e-90 1UXV-A nrPDB 327 1e-89 4I3V-A nrPDB 325 3e-89 4H7N-A nrPDB 310 1e-84 5UCD-A nrPDB 306 1e-83 4QGK-A nrPDB 305 4e-83 5NNO-A nrPDB 261 6e-70 2Y53-A nrPDB 207 1e-53 6D97-A nrPDB 204 1e-52 3K9D-A nrPDB 120 1e-27 5J7I-A nrPDB 117 1e-26 Sequences not found previously or not previously below threshold: 3V4C-A nrPDB 161 8e-40 1EZ0-A nrPDB 128 8e-30 5UJU-A nrPDB 117 1e-26 3MY7-A nrPDB 113 2e-25 5DBV-A nrPDB 103 1e-22 5JFN-A nrPDB 99 4e-21 1O20-A nrPDB 78 1e-14 4GHK-A nrPDB 70 2e-12 4JBE-A nrPDB 63 2e-10 1VLU-A nrPDB 57 2e-08 2H5G-A nrPDB 55 6e-08 1PDZ-A nrPDB 37 0.016 4YIF-A nrPDB 36 0.045 3BA0-A nrPDB 33 0.48 1JIZ-A nrPDB 33 0.50 3QTP-A nrPDB 32 0.54 5MMM-i nrPDB 32 0.83 3UJR-A nrPDB 32 0.85 4UYA-A nrPDB 32 0.87 2LKU-A nrPDB 31 1.6 1EAK-A nrPDB 31 1.6 1CK7-A nrPDB 31 1.6 1QIB-A nrPDB 31 1.9 1CXV-A nrPDB 30 2.4 6IJO-6 nrPDB 30 2.7 1FBL-A nrPDB 30 2.7 5AYP-A nrPDB 30 3.0 2DQ3-A nrPDB 30 3.0 5HM5-A nrPDB 30 3.2 2IPH-A nrPDB 30 3.3 3B97-A nrPDB 30 3.3 1WQS-A nrPDB 29 5.1 3SVK-A nrPDB 29 5.7 6DX7-A nrPDB 29 6.7 3A2Q-A nrPDB 29 7.5 2MMA-A nrPDB 28 8.3 3CZP-A nrPDB 28 10.0 >4OE4-A nrPDB Length = 580 Score = 728 bits (1879), Expect = 0.0, Method: Composition-based stats. Identities = 557/568 (98%), Positives = 562/568 (98%), Gaps = 6/568 (1%) Query: 8 KSIYFKRSFSQLGHIKPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVING 67 +++YF+ GH+KPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVING Sbjct: 13 ENLYFQ------GHMKPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVING 66 Query: 68 ERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAI 127 ERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAI Sbjct: 67 ERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAI 126 Query: 128 FLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVE 187 FLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVE Sbjct: 127 FLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVE 186 Query: 188 SADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLM 247 SADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLM Sbjct: 187 SADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLM 246 Query: 248 TVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGK 307 TVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGK Sbjct: 247 TVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGK 306 Query: 308 YRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEF 367 YRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEF Sbjct: 307 YRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEF 366 Query: 368 LSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEIL 427 LSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEIL Sbjct: 367 LSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEIL 426 Query: 428 YGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQY 487 YGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQY Sbjct: 427 YGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQY 486 Query: 488 ALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPN 547 ALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPN Sbjct: 487 ALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPN 546 Query: 548 ILSRFVSIRNTKENFYELTDFKYPSNYE 575 ILSRFVSIRNTKENFYELTDFKYPSNYE Sbjct: 547 ILSRFVSIRNTKENFYELTDFKYPSNYE 574 >5AC2-A nrPDB Length = 501 Score = 551 bits (1419), Expect = e-157, Method: Composition-based stats. Identities = 133/503 (26%), Positives = 219/503 (43%), Gaps = 34/503 (6%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK---KDWY 117 + IN E +D+ FP NPA ++ L V + ++DV AVKAA+ A W Sbjct: 21 TKIFINNEW-HDSVSGKKFPVFNPATEEE-LCQVEEGDKEDVDKAVKAARQAFQIGSPWR 78 Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA 177 + +R + K ADLI + R + + GK A ++ + RY +A Sbjct: 79 TMDASERGRLLYKLADLIE-RDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWA 137 Query: 178 SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPS 236 + + DG + G + P+NF + PAL GNTVV KP+ Sbjct: 138 DKIQGRTI--PIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPA 195 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + L+ + ++++EAG P GV+N +PG + + D + FTGST V K + Sbjct: 196 EQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIK 255 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + R+ E GGK+ +V A++ +AV G F QGQ C AASR Sbjct: 256 E-------AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASR 308 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 +++ ES +EF+ + + T GP I ++ +DK++ +IE Sbjct: 309 IFVEESIYDEFVRRSVERAKKYILGNPLTPG---------VTQGPQIDKEQYDKILDLIE 359 Query: 417 DAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNE 476 KK+ ++ GG ++G+FV PTV + E FGP+ + ++ ++ Sbjct: 360 SGKKEGA-KLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKS--LDD 416 Query: 477 ICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 536 + +N + Y L+ +F KD L+ AG ++N C G V +Q FGG +M Sbjct: 417 VIKRANN-TFYGLSAGVFTKDIDKAITISSALQ--AGTVWVN--CYGVVSAQCPFGGFKM 471 Query: 537 SGTDDKAGGPNILSRFVSIRNTK 559 SG + G + ++ Sbjct: 472 SGNGRELGE-YGFHEYTEVKTVT 493 >5AC0-A nrPDB Length = 501 Score = 546 bits (1406), Expect = e-155, Method: Composition-based stats. Identities = 130/503 (25%), Positives = 216/503 (42%), Gaps = 34/503 (6%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK---KDWY 117 + IN E + + FP NPA ++ L V + ++DV AVKAA+ A W Sbjct: 21 TKIFINNEW-HSSVSGKKFPVFNPAT-EEKLCEVEEGDKEDVDKAVKAARQAFQIGSPWR 78 Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA 177 + +R + K ADLI + R + + GK A + + RY +A Sbjct: 79 TMDASERGRLLNKLADLIE-RDRLLLATMEAMNGGKLFSNAYLMDLGGCIKTLRYCAGWA 137 Query: 178 SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPS 236 + + DG + G + P+NF + PAL GNTVV KP+ Sbjct: 138 DKIQGRTI--PMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPA 195 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + L+ + ++++EAG P GV+N +PG + + D + FTGST V K + Sbjct: 196 EQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKLIK 255 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + R+ E GGK+ +V A++ +AV +G F QGQ C AASR Sbjct: 256 E-------AAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASR 308 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 L++ ES +EF+ + + T GP I ++ ++K++ +IE Sbjct: 309 LFVEESIYDEFVRRSVERAKKYVLGNPLTPG---------VSQGPQIDKEQYEKILDLIE 359 Query: 417 DAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNE 476 KK+ ++ GG ++G+F+ PTV D E FGP+ + ++ ++ Sbjct: 360 SGKKEGA-KLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKS--LDD 416 Query: 477 ICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 536 + +N + Y L+ IF D L+ +G ++N C V +Q FGG +M Sbjct: 417 VIKRANN-TFYGLSAGIFTNDIDKAITVSSALQ--SGTVWVN--CYSVVSAQCPFGGFKM 471 Query: 537 SGTDDKAGGPNILSRFVSIRNTK 559 SG + G + ++ Sbjct: 472 SGNGRELGE-YGFHEYTEVKTVT 493 >4X2Q-A nrPDB Length = 504 Score = 543 bits (1400), Expect = e-155, Method: Composition-based stats. Identities = 134/503 (26%), Positives = 225/503 (44%), Gaps = 34/503 (6%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKK---DWY 117 + IN E + R +FP NPA +QV V +A + D+ AV+AA+ A W Sbjct: 24 TKIFINNEWQNSESGR-VFPVYNPATGEQV-CEVQEADKADIDKAVQAARLAFSLGSVWR 81 Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA 177 + +R + K ADL+ + R + L GK QA + + FRYY +A Sbjct: 82 RMDASERGRLLDKLADLVE-RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWA 140 Query: 178 SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPS 236 ++ + + + P+ G + P+NF + APAL GNTVV KP+ Sbjct: 141 DKIHGMT-IPVDGDYFTFTRHEPI-GVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPA 198 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + LS + +++EAG P GVIN +PG + + + FTGST V K + Sbjct: 199 EQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQ 258 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + R+ E GGK+ +++ A++ +AV +G F QGQ C+A SR Sbjct: 259 E-------AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 311 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 +++ ES EEF+ + + V S + GP I ++ ++K++++I+ Sbjct: 312 IFVEESIYEEFVRRSVERAKRRVVG---------SPFDPTTEQGPQIDKKQYNKILELIQ 362 Query: 417 DAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNE 476 + ++ GG+ +G+F+ PTV D E FGP+ + + +E Sbjct: 363 SGVAEGA-KLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKT--MDE 419 Query: 477 ICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 536 + + +N S + L A+F D ++ AG +IN C A+ +Q FGG +M Sbjct: 420 VIERANN-SDFGLVAAVFTNDINKALTVSSAMQ--AGTVWIN--CYNALNAQSPFGGFKM 474 Query: 537 SGTDDKAGGPNILSRFVSIRNTK 559 SG + G L + ++ Sbjct: 475 SGNGREMGE-FGLREYSEVKTVT 496 >4LGZ-A nrPDB Length = 563 Score = 543 bits (1398), Expect = e-154, Method: Composition-based stats. Identities = 230/544 (42%), Positives = 326/544 (59%), Gaps = 15/544 (2%) Query: 27 HIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPAN 86 + NEP+ F + D L+ +L K + +P V+ E ++ ++ + Q +P N Sbjct: 31 KVANEPILAFSQ-GSPERDALQKALKDLKGQTEAIPCVVGDEEVWTSDIQY---QLSPFN 86 Query: 87 HQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAA 146 H +A A + + A+ AA A+K+W P DR+ +FLKAAD++S R ++LA Sbjct: 87 HAHKVAKFCYADKALLNRAIDAALAARKEWDLKPMADRAQVFLKAADMLSGPRRAEVLAK 146 Query: 147 TMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVY 206 TM+GQGK V QAEID EL DFFR+ K+A +L +QP+ T N YR LEGFV Sbjct: 147 TMVGQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPST-NHTVYRGLEGFVA 205 Query: 207 AVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGD 266 A+SPFNFTAI NL GAPALMGN V+WKPS TA L++Y + +L EAGLP +I F+P D Sbjct: 206 AISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPAD 265 Query: 267 PVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLV 326 D V + + ++FTGS FK L+ ++ + ++R +PR+ GE GGKNFH V Sbjct: 266 GPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNL--DRFRTFPRLAGECGGKNFHFV 323 Query: 327 HPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTS 386 H SA++ V T+R FE+ GQKCSA SRLY+P+S + + V Sbjct: 324 HSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDP--- 380 Query: 387 ASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIK 446 + F VI ++F ++ K +E A+ P L IL GGQ ++S G++V P +I+ Sbjct: 381 -----AEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIE 435 Query: 447 AKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADE 506 +K P P M E FGP+LTVY YPD ++ E ++D+T+ Y LTGA+FA+D+ ++ A Sbjct: 436 SKDPQEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATR 495 Query: 507 KLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELT 566 L+ +AGNFYINDK TG+VV QQ FGGAR SGT+DK GGP+ + R+ S + KE L Sbjct: 496 MLRNAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLG 555 Query: 567 DFKY 570 D++Y Sbjct: 556 DWRY 559 >3V9H-A nrPDB Length = 566 Score = 541 bits (1395), Expect = e-154, Method: Composition-based stats. Identities = 230/544 (42%), Positives = 323/544 (59%), Gaps = 15/544 (2%) Query: 27 HIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPAN 86 + NEPV F + D L+ +L K +P V+ E ++ ++ + Q +P N Sbjct: 34 KVANEPVLAFTQ-GSPERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQY---QVSPFN 89 Query: 87 HQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAA 146 H +A A + + A++AA A+K+W P DR+ IFLKAAD++S R ++LA Sbjct: 90 HGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAK 149 Query: 147 TMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVY 206 TM+GQGK V QAEID EL DFFR+ KYA +L QQP+ T N YR LEGFV Sbjct: 150 TMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPST-NSTVYRGLEGFVA 208 Query: 207 AVSPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGD 266 A+SPFNFTAI NL GAPALMGN V+WKPS TA L++Y + +L EAGLP +I F+P D Sbjct: 209 AISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPAD 268 Query: 267 PVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLV 326 D V + + ++FTGS FK L+ ++ + ++ +PR+ GE GGKNFH V Sbjct: 269 GPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNL--DRFHTFPRLAGECGGKNFHFV 326 Query: 327 HPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTS 386 H SA++ V T+R FE+ GQKCSA +RLY+P S + + V Sbjct: 327 HRSADVESVVSGTLRSAFEYGGQKCSACARLYVPHSLWPQIKGRLLEEHSRIKVGDP--- 383 Query: 387 ASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIK 446 + F VI +SF ++ K +E A+ P L IL GG+ D S G+FV P +++ Sbjct: 384 -----AEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVE 438 Query: 447 AKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADE 506 +K P P M E FGP+L+VY YPD ++ E ++D+T+ Y LTGA+F++D+ ++ A + Sbjct: 439 SKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATK 498 Query: 507 KLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELT 566 L+ +AGNFYINDK TG++V QQ FGGAR SGT+DK GGP+ + R+ S + KE L Sbjct: 499 VLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLG 558 Query: 567 DFKY 570 D+ Y Sbjct: 559 DWSY 562 >5L13-A nrPDB Length = 517 Score = 537 bits (1384), Expect = e-153, Method: Composition-based stats. Identities = 129/502 (25%), Positives = 223/502 (44%), Gaps = 34/502 (6%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK---KDWYN 118 + IN E +D R FP NP+ + V+ V + ++DV AVKAA+ A W Sbjct: 38 QIFINNEW-HDAVSRKTFPTVNPSTGE-VICQVAEGDKEDVDKAVKAARAAFQLGSPWRR 95 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 + R + + ADLI + R + A L GK + + + + RYY +A Sbjct: 96 MDASHRGRLLNRLADLIE-RDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWAD 154 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 + + + ++ + P+ G + P+NF + PAL GN VV K ++ Sbjct: 155 KYHGKT-IPIDGDFFSYTRHEPV-GVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAE 212 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 L+ + +++EAG P GV+N +PG + + +D + FTGST + + + Sbjct: 213 QTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ- 271 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 V + R+ E GGK+ +++ A++ AV F QGQ C A SR Sbjct: 272 ------VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRT 325 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 ++ E +EF+ +S+ V +P + + GP + E F K++ I Sbjct: 326 FVQEDIYDEFVERSVARAKSRVV------GNPF---DSKTEQGPQVDETQFKKILGYINT 376 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 K++ ++L GG +G+F+ PTV + E FGP++ + ++ E E+ Sbjct: 377 GKQEGA-KLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIE--EV 433 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 +N++ Y L A+F KD Y + L+ AG ++N C +Q FGG +MS Sbjct: 434 VGRANNST-YGLAAAVFTKDLDKANYLSQALQ--AGTVWVN--CYDVFGAQSPFGGYKMS 488 Query: 538 GTDDKAGGPNILSRFVSIRNTK 559 G+ + G L + ++ Sbjct: 489 GSGRELGE-YGLQAYTEVKTVT 509 >5FHZ-A nrPDB Length = 529 Score = 536 bits (1380), Expect = e-152, Method: Composition-based stats. Identities = 135/503 (26%), Positives = 228/503 (45%), Gaps = 34/503 (6%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK---KDWY 117 + IN E +++ F NP+ +Q + V + + DV AV+AA+ A W Sbjct: 49 TKIFINNEW-HESKSGKKFATCNPSTREQ-ICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 106 Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA 177 L R + + ADL+ + R + A + GK A + RY+ +A Sbjct: 107 RLDALSRGRLLHQLADLVE-RDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWA 165 Query: 178 SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPS 236 + + + + D + P+ G A++P+NF + APAL GNT+V KP+ Sbjct: 166 DKIQGKT-IPTDDNVVCFTRHEPI-GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA 223 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + L+ L ++++EAG P GV+N +PG V + + + FTGST V K + Sbjct: 224 EQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVK 283 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + R+ E GGKN +V A++ AV +G F QGQ C+AASR Sbjct: 284 E-------AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 336 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 +++ E EF+ + + V P +++ GP I ++ FDK++++IE Sbjct: 337 VFVEEQVYSEFVRRSVEYAKKRPV------GDPF---DVKTEQGPQIDQKQFDKILELIE 387 Query: 417 DAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNE 476 KK+ ++ GG + +G F+ PTV + E FGP+ + ++ E E Sbjct: 388 SGKKEGA-KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIE--E 444 Query: 477 ICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 536 + N++ Y LT A+F K+ L+ +G +IN C A+ +Q FGG +M Sbjct: 445 VIKR-ANSTDYGLTAAVFTKNLDKALKLASALE--SGTVWIN--CYNALYAQAPFGGFKM 499 Query: 537 SGTDDKAGGPNILSRFVSIRNTK 559 SG + G L+ + ++ Sbjct: 500 SGNGRELGE-YALAEYTEVKTVT 521 >1AG8-A nrPDB Length = 499 Score = 531 bits (1367), Expect = e-151, Method: Composition-based stats. Identities = 132/502 (26%), Positives = 223/502 (44%), Gaps = 34/502 (6%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK---KDWYN 118 + IN E +D + FP NP+ V+ +V + + DV AVKAA+ A W Sbjct: 20 QIFINNEW-HDAVSKKTFPTVNPSTGD-VICHVAEGDKADVDRAVKAARAAFQLGSPWRR 77 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 + +R + + ADLI + R + A L GK + + + + RYY +A Sbjct: 78 MDASERGRLLNRLADLIE-RDRTYLAALETLDNGKPYIISYLVDLDMVLKCLRYYAGWAD 136 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 + + + ++ + P+ G + P+NF + PAL GN VV K ++ Sbjct: 137 KYHGKT-IPIDGDYFSYTRHEPV-GVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAE 194 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 L+ + +++EAG P GV+N IPG + + +D + FTGST V + Sbjct: 195 QTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQ- 253 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 V + R+ E GGK+ +++ A++ AV F QGQ C A SR Sbjct: 254 ------VAAGKSNLKRVTLEIGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRT 307 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 ++ E EF+ +S+ V +P + R GP + E F K++ I+ Sbjct: 308 FVQEDIYAEFVERSVARAKSRVV------GNPF---DSRTEQGPQVDETQFKKVLGYIKS 358 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 K++ L++L GG +G+F+ PTV + E FGP++ + ++ E E+ Sbjct: 359 GKEEG-LKLLCGGGAAADRGYFIQPTVFGDLQDGMTIAKEEIFGPVMQILKFKSME--EV 415 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 +N S+Y L A+F KD Y + L+ AG ++N C +Q FGG ++S Sbjct: 416 VGRANN-SKYGLAAAVFTKDLDKANYLSQALQ--AGTVWVN--CYDVFGAQSPFGGYKLS 470 Query: 538 GTDDKAGGPNILSRFVSIRNTK 559 G+ + G L + ++ Sbjct: 471 GSGRELGE-YGLQAYTEVKTVT 491 >5GT6-A nrPDB Length = 508 Score = 528 bits (1360), Expect = e-150, Method: Composition-based stats. Identities = 135/502 (26%), Positives = 230/502 (45%), Gaps = 34/502 (6%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKK--DWY 117 E+ + INGE + F NPA + VLA V +A E+D+ AVKAA+ A + W Sbjct: 33 EIKMFINGEFV-SAIGGKTFETYNPAT-EDVLAVVCEAQEEDIDAAVKAARSAFESGPWA 90 Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYA 177 + +R+ + K ADLI ++R ++ L GK A D I+ + +RYY + Sbjct: 91 EMTTAERAHLIYKLADLIE-EHREELAQLEALDNGKPYQVALDDDISATVENYRYYAGWT 149 Query: 178 SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPS 236 + + Q S D N + P+ G V + P+NF + ++ AL G T+V KP+ Sbjct: 150 TKIIGQTIPISKD-YLNYTRHEPV-GVVGQIIPWNFPLVMSSWKMGAALATGCTIVLKPA 207 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + LS + +EAG P GV+NF+PG + ++ D + FTGST K + Sbjct: 208 EQTPLSLLYAAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDKVAFTGSTVTGKYIM 267 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + + + E GGK+ +++ A++ A+ +G GQ CSA SR Sbjct: 268 RQSAEMI--------KHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQNCSAGSR 319 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 +++ E + + + + + +G MGP++ ++ ++++ IE Sbjct: 320 VFVHRKHYETVVDALVKMANNVKLG---------AGMEKETEMGPLVSKKQQERVLNYIE 370 Query: 417 DAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNE 476 KK+ + GG+ +G+FV PTV D + E FGP++ V + TE E Sbjct: 371 QGKKEGAT-VAAGGERALEKGYFVKPTVFTDVTDDMTIVKEEIFGPVVVVLPFDSTE--E 427 Query: 477 ICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 536 + + +N+S Y L ++ ++ K KLK AG +IND + FGG + Sbjct: 428 VIERANNSS-YGLAAGVWTQNIKTGHQVANKLK--AGTVWINDYNL--ENAAAPFGGYKQ 482 Query: 537 SGTDDKAGGPNILSRFVSIRNT 558 SG + G L + +++ Sbjct: 483 SGIGRELGS-YALDNYTEVKSV 503 >1O9J-A nrPDB Length = 501 Score = 524 bits (1350), Expect = e-149, Method: Composition-based stats. Identities = 131/509 (25%), Positives = 220/509 (43%), Gaps = 34/509 (6%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK---KDW 116 L IN E +++ FP NPA ++ + V +A ++DV AVKAA++A W Sbjct: 20 HTKLFINNEW-HESVSGKTFPVFNPAT-EEKICEVEEADKEDVDKAVKAAREAFQMGSPW 77 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 + +R + K ADLI + R + + GK A + + RY + Sbjct: 78 RTMDASERGQLIYKLADLIE-RDRLLLATLESINAGKVFASAYLMDLDYCIKALRYCAGW 136 Query: 177 ASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKP 235 A + + DG + G + P+N I PAL GNTV+ KP Sbjct: 137 ADKIQGRTI--PVDGEFFSYTRHEPIGVCGLIFPWNAPMILLACKIGPALCCGNTVIVKP 194 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 ++ L+ + ++++EAG P GV+N +PG + + D + FTGST V K + Sbjct: 195 AEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKMI 254 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAAS 355 + R+ E G KN +V A++ AV +G F QGQ C AAS Sbjct: 255 QE-------AAAKSNLKRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAAS 307 Query: 356 RLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415 +L++ E+ +EF+ + +P++ G GP I++ +K++++I Sbjct: 308 KLFVEEAIYDEFVQRSVERAKK------YVFGNPLTPG---VNHGPQINKAQHNKIMELI 358 Query: 416 EDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 E KK+ ++ GG ++G+F+ PTV D E FGP+ + ++ + Sbjct: 359 ESGKKEGA-KLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKS--LD 415 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 E+ +N + Y L +F KD L+ AG ++N C A +Q GG + Sbjct: 416 EVIKRANN-TYYGLVAGVFTKDLDKAVTVSSALQ--AGTVWVN--CYLAASAQSPAGGFK 470 Query: 536 MSGTDDKAGGPNILSRFVSIRNTKENFYE 564 MSG + G + + ++ E Sbjct: 471 MSGHGREMGE-YGIHEYTEVKTVTMKISE 498 >3QAN-A nrPDB Length = 538 Score = 524 bits (1350), Expect = e-149, Method: Composition-based stats. Identities = 180/544 (33%), Positives = 278/544 (51%), Gaps = 29/544 (5%) Query: 22 IKPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQ 81 ++P KH EP F ++ A + K E PL+INGER+ ++ Sbjct: 3 LQPYKH---EPFTDF-TVEANRKAFEEALGLVEKELGKEYPLIINGERVTTEDK---IQS 55 Query: 82 TNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRY 141 NPA Q++ +V++A + A+++A +A + W N+ +R+ I +KAA +I + ++ Sbjct: 56 WNPARKDQLVGSVSKANQDLAEKAIQSADEAFQTWRNVNPEERANILVKAAAIIRRR-KH 114 Query: 142 DMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPL 201 + A + GK +A+ D E DF YY + +L + + S G N+ Y P+ Sbjct: 115 EFSAWLVHEAGKPWKEADADT-AEAIDFLEYYARQMIELNRGKEILSRPGEQNRYFYTPM 173 Query: 202 EGFVYAVSPFNFTA-IAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVI 260 G +SP+NF I AP + GNTVV KP+ T + + VLE+AGLPKGVI Sbjct: 174 -GVTVTISPWNFALAIMVGTAVAPIVTGNTVVLKPASTTPVVAAKFVEVLEDAGLPKGVI 232 Query: 261 NFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGG 320 N++PG +V D ++ + FTGS +V LY + VV R+I E GG Sbjct: 233 NYVPGSGAEVGDYLVDHPKTSLITFTGSKDVGVRLYERAA--VVRPGQNHLKRVIVEMGG 290 Query: 321 KNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNV 380 K+ +V A++ A S + F F GQKCSA SR + + +E L + ++ V Sbjct: 291 KDTVVVDRDADLDLAAESILVSAFGFSGQKCSAGSRAVIHKDVYDEVLEKTVALAKNLTV 350 Query: 381 VPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFV 440 N +MGPVI E++F+K++ IE KK+ ++ GG+ D S G+F+ Sbjct: 351 GDPT---------NRDNYMGPVIDEKAFEKIMSYIEIGKKEG--RLMTGGEGDSSTGFFI 399 Query: 441 GPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKA 500 PT+I P+ M E FGP++ + D F+ +I +N ++Y LTGA+ ++R Sbjct: 400 QPTIIADLDPEAVIMQEEIFGPVVAFSKAND--FDHALEIANN-TEYGLTGAVITRNRAH 456 Query: 501 IEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKE 560 IE A +F GN Y N CTGA+V FGG +MSGTD KAGGP+ L+ + + E Sbjct: 457 IEQAKR--EFHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAGGPDYLALHMQAKTVSE 514 Query: 561 NFYE 564 + E Sbjct: 515 MYAE 518 >3RJL-A nrPDB Length = 538 Score = 516 bits (1328), Expect = e-146, Method: Composition-based stats. Identities = 176/535 (32%), Positives = 271/535 (50%), Gaps = 28/535 (5%) Query: 34 KPFRNIDLKD-WDLLRASLMKFKSSSL--EVPLVINGERIYDNNERALFPQTNPANHQQV 90 +PF N +++ +L + L PLVI+GER N+ NPAN ++V Sbjct: 8 EPFTNFGIEENRKAFEKALETVNNEWLGQSYPLVIDGERYETENK---IVSINPANKEEV 64 Query: 91 LANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLG 150 + V++AT+ A++AA A + W +R+A+ +A + K +++ A + Sbjct: 65 VGTVSKATQDHAEKAIQAAAKAFETWRYTDPEERAAVLFRAVAKVRRK-KHEFSALLVKE 123 Query: 151 QGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSP 210 GK +A+ D E DF YY + +L +PV S +G N+ Y P G + P Sbjct: 124 AGKPWNEADADT-AEAIDFMEYYARQMIELAKGKPVNSREGERNQYVYTP-TGVTVVIPP 181 Query: 211 FNFT-AIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQ 269 +NF AI A AP + GNTVV KP+ A + + VLEE+GLPKGV+NF+PG + Sbjct: 182 WNFLFAIMAGTTVAPIVTGNTVVLKPASAAPVIAAKFVEVLEESGLPKGVVNFVPGSGAE 241 Query: 270 VTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPS 329 V D ++ + FTGS V ++ + V+ ++I E GGK+ +V Sbjct: 242 VGDYLVDHPKTSIITFTGSREVGTRIFERAAK--VQPGQTHLKQVIAEMGGKDTVVVDED 299 Query: 330 ANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASP 389 +I A S F F GQKCSA SR + E +E L + I +S+ V + Sbjct: 300 CDIELAAQSIFTSAFGFAGQKCSAGSRAVVHEKVYDEVLKRVIEITESKKVGEPD----- 354 Query: 390 ISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKR 449 + +MGPVI + SF+K++ IE K++ ++ GG+ D S+G+F+ PT+ Sbjct: 355 ----SADVYMGPVIDQASFNKIMDYIEIGKEEG--RLVSGGKGDDSKGYFIEPTIFADLD 408 Query: 450 PDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLK 509 P M E FGP++ + F+E ++ +N ++Y LTGA+ K+R I A + + Sbjct: 409 PKARLMQEEIFGPVVAFSKVSS--FDEALEVANN-TEYGLTGAVITKNRDHINRAKQ--E 463 Query: 510 FSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 F GN Y N CTGA+V FGG +MSGTD KAGGP+ L+ + + E F E Sbjct: 464 FHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAGGPDYLALHMQAKTISEMFAE 518 >4V3F-A nrPDB Length = 497 Score = 512 bits (1319), Expect = e-145, Method: Composition-based stats. Identities = 134/510 (26%), Positives = 229/510 (44%), Gaps = 37/510 (7%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKK--DWYNL 119 L I+GE + ++ P NP+ ++++ ++ AT +DV AV AA+ A + +W Sbjct: 9 QLFIDGEW-REPIKKNRIPVINPST-EEIIGDIPAATAEDVEVAVVAARRAFRRNNWSAT 66 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 R+ A I T+ + + + GK +A +D I +++ F Y+ A Sbjct: 67 SGAHRATYLRAIAAKI-TEKKDHFVKLETIDSGKPFDEAVLD-IDDVASCFEYFAGQAEA 124 Query: 180 LYAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPS 236 L +Q PV + R G V +SP+N+ + A APAL G T V KPS Sbjct: 125 LDGKQKAPVTLPMERFKSHVLRQPLGVVGLISPWNYPLLMATWKIAPALAAGCTAVLKPS 184 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + A+++ V E GLP GV+N + G +++ D + FTGS+ Sbjct: 185 ELASVTCLEFGEVCNEVGLPPGVLNILTGLGPDAGAPLVSHPDVDKIAFTGSSATG---- 240 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 S V+ + + E GGK+ +V +I V TI G F GQ CSA SR Sbjct: 241 ----SKVMASAAQLVKPVTLELGGKSPIVVFEDVDIDKVVEWTIFGCFWTNGQICSATSR 296 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 L + ES + EF+ + ++ + + P G +GPVI + +DK++K I Sbjct: 297 LLVHESIAAEFVDKLVKWTKNIKI------SDPFEEGCR---LGPVISKGQYDKIMKFIS 347 Query: 417 DAKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEF 474 AK + ILYGG + +G+++ PT++ E FGP+L V + Sbjct: 348 TAKSEGAT-ILYGGSRPEHLKKGYYIEPTIVTDISTSMQIWKEEVFGPVLCVKTFSS--- 403 Query: 475 NEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGA 534 + + N ++Y L A+F+ D + E + L+ G ++N C+ Q +GG Sbjct: 404 EDEAIALANDTEYGLAAAVFSNDLERCERITKALEV--GAVWVN--CSQPCFVQAPWGGI 459 Query: 535 RMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 + SG + G + +++I+ ++ + Sbjct: 460 KRSGFGRELGEW-GIQNYLNIKQVTQDISD 488 >5UR2-A nrPDB Length = 984 Score = 508 bits (1308), Expect = e-144, Method: Composition-based stats. Identities = 167/540 (30%), Positives = 278/540 (51%), Gaps = 27/540 (5%) Query: 23 KPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQT 82 K P NEP+ F + +L+A S + V +VIN + + +F + Sbjct: 460 KKPGKFYNEPLLDFA-VKADREKMLKALAEAKASLPVNVNIVINNKELQS---GKIFDRV 515 Query: 83 NPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYD 142 NP+ Q++ + AT + A++AA+ A K W N+P R+A+ K AD++ T+ R+ Sbjct: 516 NPSQSDQIVGKIQMATTEQAEQAMQAAQTAYKTWKNVPCEQRAALVDKLADIM-TRDRFK 574 Query: 143 MLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLE 202 ++A +L GK +A+ D I E DF RYY ++ +L V G + Y+ Sbjct: 575 LIATQVLEVGKPWAEADGD-IGEAIDFCRYYARHMRELQKPLRVGGLPGELSHYIYK-SR 632 Query: 203 GFVYAVSPFNFTA-IAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVIN 261 G ++P+NF I A ++ A A+ GNTVV KP++ + + + LM +++EAG P+GVIN Sbjct: 633 GVTAVIAPWNFPLAILAGMVTAAAVAGNTVVMKPAEQSTVVAWGLMKMIQEAGFPQGVIN 692 Query: 262 FIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGK 321 F+PG +V + ++ K + FTGS V + + VV+ + R I E GGK Sbjct: 693 FLPGYGEEVGEYIVNHKYTTTIAFTGSKAVGLHIMNRAA--VVQPGQQHVKRCIIEMGGK 750 Query: 322 NFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVV 381 N ++ A++ AV I F F GQKCSAASR+ + + + F+ + +S + Sbjct: 751 NAVIIDNDADLDEAVDGVIYSAFGFSGQKCSAASRVIVLDEVYDRFVDRLVETAKSIEIH 810 Query: 382 PMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVG 441 P N + +MGPV+ ++++D+++ I +A+K+ ++L+ G G+F Sbjct: 811 P---------AENPKAYMGPVVDKEAYDRILGTIAEAEKNH--KLLFKGSVP-GGGFFAP 858 Query: 442 PTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAI 501 PT+ D E FGP++ V + ++ D I N+++YALTG +F++ I Sbjct: 859 PTIFGDVPGDAKLAQAEIFGPVVAVIRAKN--LDQALD-IANSTEYALTGGVFSRSPANI 915 Query: 502 EYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKEN 561 E+L+ GN Y+N TGA+V + FGG +MSG K GGP+ L +++ EN Sbjct: 916 NRVKEELEV--GNLYVNRGITGAMVDRHPFGGFKMSGIGSKTGGPDYLKQYMEPACVTEN 973 >4CAZ-A nrPDB Length = 490 Score = 504 bits (1299), Expect = e-143, Method: Composition-based stats. Identities = 124/514 (24%), Positives = 217/514 (42%), Gaps = 36/514 (7%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119 E L I G + + + A F NPAN + VLA V +A+ +DV AV++A + +K W + Sbjct: 6 EQKLYIGGRYV-EASSGATFETINPANGE-VLAKVQRASREDVERAVQSAVEGQKVWAAM 63 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 RS I +A D++ + ++ A L GK + + I +D YY Sbjct: 64 TAMQRSRILRRAVDILRERN-DELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPA 122 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQT 238 + +Q + + ++ PL G V + +N+ A APAL GN +++KPS+ Sbjct: 123 IEGEQ-IPLRETSFVYTRREPL-GVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEV 180 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 L+ L + EAG+P GV N + G +V + + FTG T+ K + Sbjct: 181 TPLTALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMAS 240 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 S + E GGK+ ++ P A++ A + F GQ C+ +R++ Sbjct: 241 ASSS-------SLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVF 293 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + S+ F + + +Q + + GP++ + ++ IE Sbjct: 294 IHRSQQARFEAKVLERVQRIRLGDPQ---------DENTNFGPLVSFPHMESVLGYIESG 344 Query: 419 KKDPELEILYGGQYDK---SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 K + G + +G +V PTV R D + E FGP++++ Y D + Sbjct: 345 KAQKARLLCGGERVTDGAFGKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDE--D 402 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 E N ++Y L + +D A +L+ AG +IN G ++ GG + Sbjct: 403 EAIRR-ANDTEYGLAAGVVTQDLARAHRAIHRLE--AGICWIN--TWGESPAEMPVGGYK 457 Query: 536 MSGTDDKAGGPNILSRFVSIRNTKENFYELTDFK 569 SG + G L+ + I++ + EL D+ Sbjct: 458 QSGVGRENG-LTTLAHYTRIKSVQ---VELGDYA 487 >4PZ2-A nrPDB Length = 534 Score = 500 bits (1287), Expect = e-142, Method: Composition-based stats. Identities = 122/507 (24%), Positives = 223/507 (43%), Gaps = 34/507 (6%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK--KDWYN 118 L ING + D F +P V+A+V +A ++DV AV+AA+ A +W Sbjct: 51 TKLFINGSFV-DAVSGRTFDTRDPRTGG-VIASVAEADKEDVDLAVRAARAAFDHGEWPR 108 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 + +R I + ADL+ ++ ++ A L GK+ + + RY+ A Sbjct: 109 MSGSERGRIMARLADLVE-EHAGELAALESLDAGKHPAVTRAVDVGNAAGSLRYFAGAAD 167 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 ++ + G + R G + P+NF + + APAL G +V KP++ Sbjct: 168 KIHGET--LKMPGQFQGHTLREPLGVAGVIIPWNFPSTMFAVKVAPALAAGCALVVKPAE 225 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 LS L + ++AG+P GVIN +PG + + D + FTGST V + + Sbjct: 226 QTPLSALYLAQLAKQAGVPDGVINVVPGFGPTAGAALASHMDVDMVSFTGSTEVGRLIMK 285 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 + + E GGK+ +V A++ AV + +F +G+ C AASR+ Sbjct: 286 -------ASAESNLKPVYLELGGKSPLIVFDDADLDMAVELAVGASFFNKGEACVAASRV 338 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 Y+ E + F + ++S V P S + R GP + + +++++ I+ Sbjct: 339 YVQERVYDRFEERLAERMRSWVV------GDPFS--DPRADQGPQVDKAQYERVLSYIDH 390 Query: 418 AKKDPELEILYGGQY--DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 K++ +L GG+ + +G+++ PTV + D E FGP++ + ++ Sbjct: 391 GKREGAT-LLTGGRPCAPEGKGYYIEPTVFTNVKEDMIIAKEEIFGPVMCLMKFKTV--- 446 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 E N ++Y L + +D ++ AG ++N C A+ S FGG + Sbjct: 447 EEAIARANDTRYGLGAGVVTRDLDVANRVVRSVR--AGVVWVN--CYFAMGSDCPFGGRK 502 Query: 536 MSGTDDKAGGPNILSRFVSIRNTKENF 562 MSG G + L +++++++ Sbjct: 503 MSGFGKDEG-MHALDKYLAVKSVVTPL 528 >4O6R-A nrPDB Length = 496 Score = 497 bits (1281), Expect = e-141, Method: Composition-based stats. Identities = 130/505 (25%), Positives = 209/505 (41%), Gaps = 36/505 (7%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 ++ L I+G + D +R NP + V+ + AT DV AV AA A W Sbjct: 9 MQTQLFIDGRFV-DAVDRGTIDVLNPHDGS-VITKIAAATAADVDLAVDAATRAFPAWSA 66 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 +P +R + L+ AD I + L G + + + + FRY+ A Sbjct: 67 MPAAERGRLLLRLADAIEANTEA-LAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMAD 125 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 L + G N + P+ G V + P+NF + + PAL GNTVV KPS+ Sbjct: 126 KLQGSV-IPVDTGFLNYVQRAPI-GVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSE 183 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 LS ++ ++ E G P GV+N +PG ++ G + FTGST + + Sbjct: 184 ITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRI-- 241 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 VE + R+ E GGK ++V AN+ A+ F QGQ C A SRL Sbjct: 242 ------VEASQGNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRL 295 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 L E ++ FL + S + + + MGP+ +Q D+++ ++ Sbjct: 296 VLHERIADAFLERFVALASSIRIG---------NPLDPNTEMGPLTSKQHLDRVLSYVDV 346 Query: 418 AKKDPELEILYGGQYDKS----QGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 A++ +L GG + G++V PT+++AK E FGP +TV + Sbjct: 347 AREQGG-RVLTGGSAPQDPALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGS-- 403 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 ++ I N ++Y L ++ D + AG +IN C V FGG Sbjct: 404 -DDEALAIANATEYGLGSGLWTNDLSRAHRMAA--RIDAGMCWIN--CYKRVNPGSPFGG 458 Query: 534 ARMSGTDDKAGGPNILSRFVSIRNT 558 SG + G + + R+ Sbjct: 459 VGKSGYGREMG-FEAMHDYTEARSV 482 >4PXL-B nrPDB Length = 517 Score = 497 bits (1280), Expect = e-141, Method: Composition-based stats. Identities = 124/506 (24%), Positives = 216/506 (42%), Gaps = 33/506 (6%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK--KDWYN 118 L I+G+ + D F +P + V+A++ + + DV AVKAA++A W Sbjct: 37 TKLFIDGKFV-DAVSGKTFETRDPRTGE-VIASIAEGDKADVDLAVKAAREAFDNGPWPR 94 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 + Y+R I + ADLI ++ ++ A + GK + I + RYY A Sbjct: 95 MTGYERGRILHRFADLI-DEHVEELAALDTVDAGKLFAVGKARDIPGAAHLLRYYAGAAD 153 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 ++ ++ A P+ G V + P+N+ PAL G VV KP++ Sbjct: 154 KVHGAT-LKMAQRMHGYTLKEPV-GVVGHIVPWNYPTTMFFFKVGPALAAGCAVVVKPAE 211 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 LS + EAG+P GV+N +PG V A D + FTGST V + + Sbjct: 212 QTPLSALFYAHLAREAGVPAGVLNVVPGFGPTAGAAVAAHMDVDKVSFTGSTEVGRLVMR 271 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 + + E GGK+ +V A++ AV T+ +G+ C A +R+ Sbjct: 272 -------AAAESNLKPVSLELGGKSPVIVFDDADLDMAVNLVNFATYTNKGEICVAGTRI 324 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 Y+ E +EF+ + V P N GP + + ++K+++ I+ Sbjct: 325 YVQEGIYDEFVKKAAELASKSVV------GDPF---NPSVSQGPQVDKDQYEKVLRYIDI 375 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 K++ ++ GG+ +G+++ PT+ + D E FGP++ + ++ E E+ Sbjct: 376 GKREGAT-LVTGGKPCGDKGYYIEPTIFTDVKDDMTIAQDEIFGPVMALMKFKTVE--EV 432 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 +N ++Y L I K+ ++ AG +IN C A FGG +MS Sbjct: 433 IQKANN-TRYGLAAGIVTKNIDVANTVSRSIR--AGAIWIN--CYFAFDPDAPFGGYKMS 487 Query: 538 GTDDKAGGPNILSRFVSIRNTKENFY 563 G K G + L +++ + Y Sbjct: 488 GFG-KDMGMDALDKYLQTKTVVTPLY 512 >4QYJ-A nrPDB Length = 516 Score = 492 bits (1267), Expect = e-139, Method: Composition-based stats. Identities = 130/528 (24%), Positives = 222/528 (42%), Gaps = 42/528 (7%) Query: 42 KDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKD 101 + +SL L ++I G+ + + NPA +L V +D Sbjct: 16 PRGSHMNSSLSAIDGLRLPHQMLIGGQWVSAQS-GKTLNVYNPATGD-ILTEVPDGDVED 73 Query: 102 VMNAVKAAKDAKK--DWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAE 159 V AV++A + W +P R I L+ ADL+ + ++ L GK + ++ Sbjct: 74 VNAAVESAAATLRSDTWRRMPPSARERILLRLADLLEV-HGDELARLETLNNGKLLIYSK 132 Query: 160 IDCITELSDFFRYYVKYASDLYAQQ-----PVESADGTWNKAEYRPLEGFVYAVSPFNFT 214 + + + + RY +A+ L P+ + + P+ G V A+ P+NF Sbjct: 133 LMEVGASAQWLRYMAGWATKLTGSTLDLSLPLPPEVRSRASTQRVPV-GVVAAIIPWNFP 191 Query: 215 AIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQ 273 + A APAL GNTVV KP++ L+ L + EAGLP G +N + G D Sbjct: 192 LLMAVWKIAPALACGNTVVLKPAEETPLTALRLAELAMEAGLPAGALNVVTGRGETAGDA 251 Query: 274 VLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANIS 333 ++ + FTGST V + + R + E GGK+ +V + Sbjct: 252 LVRHPKVAKVAFTGSTEVGRII--------GSACGRSLKAVSLELGGKSPVIVLADCDPQ 303 Query: 334 HAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGG 393 A F GQ C+A SRLY+ ES E+ + + I +S V Sbjct: 304 EAAEGAAAAIFFNHGQVCTAGSRLYVHESIYEDVIQRLAVIGESIVVGSGLEQG------ 357 Query: 394 NLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKA-KRPDH 452 MGP++ ++ + +++ I + +D I G + +QG+FV PT+ ++ D Sbjct: 358 ---VHMGPMVSKKHHENVLRHIRNGIEDGADLICGGTEAPCAQGFFVKPTIFANREKKDI 414 Query: 453 PYMSTEFFGPILTVYEYPDTEFNEICDIID--NTSQYALTGAIFAKDRKAIEYADEKLKF 510 +S E FGP+L + D I ++++ N S Y L +I+ D A +++L+ Sbjct: 415 RLLSQEVFGPVLVATPFSD-----IAEVVNEANRSVYGLGASIWTNDLSAALRINDELE- 468 Query: 511 SAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 AG ++N V FGG + SG + G + + + R+ Sbjct: 469 -AGTVWVNTHNM--VDPNLPFGGFKDSGVGREHGA-AAIEHYTTTRSL 512 >3IWK-A nrPDB Length = 503 Score = 488 bits (1257), Expect = e-138, Method: Composition-based stats. Identities = 130/511 (25%), Positives = 226/511 (44%), Gaps = 42/511 (8%) Query: 62 PLVINGER-IYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA-----KKD 115 L I+GE + N+R P NP+ + ++ ++ AT++DV AV AAK A +D Sbjct: 9 QLFIDGEWRVPILNKR--IPNINPST-ENIIGDIPAATKEDVDLAVDAAKRAISRKNGRD 65 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W R+ A I + + ++ + GK + +A D + ++ F YY Sbjct: 66 WSAASGSLRARYLRAIAAKI-KEKKDELGKLESIDCGKPLEEALAD-LDDVVACFEYYAG 123 Query: 176 YASDLYAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTV-V 232 A +L ++Q P+ T+ + G V ++P+N+ + A APAL + Sbjct: 124 LAEELDSKQKAPISLPMDTFKSYILKEPIGVVALITPWNYPFLMATWKIAPALAAGCAAI 183 Query: 233 WKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVF 292 KPS+ A+++ L + +E GLP+GV+N + G + + + D + FTGS+ Sbjct: 184 LKPSELASVTCLELGEICKEVGLPRGVLNIVTGLGHEAGASLASHPDVDKISFTGSSATG 243 Query: 293 KSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCS 352 S ++ + + E GGK+ +V ++ T+ G F GQ CS Sbjct: 244 --------SKIMTTAAQLVKPVSLELGGKSPIVVFEDVDLDKVAEWTVFGCFFTNGQICS 295 Query: 353 AASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLV 412 A SRL + ES + EF+ + ++ + + P+ G +GP++ E + K++ Sbjct: 296 ATSRLIVHESIAVEFVDKLVKWAENIKI------SDPLEEGCR---LGPIVSEAQYKKVL 346 Query: 413 KVIEDAKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP 470 I AK + IL GG+ + +G+FV PT+I E FGP+L V + Sbjct: 347 NCISSAKSEGAT-ILTGGRRPEHLKKGYFVEPTIITDVTTSMQIWREEVFGPVLAVKTFS 405 Query: 471 DTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW 530 E + N + Y L A+ + D + E + L+ AG +IN C Q Sbjct: 406 T---EEEAINLANDTHYGLGSAVMSNDLERCERLSKALQ--AGIVWIN--CAQPSFIQAP 458 Query: 531 FGGARMSGTDDKAGGPNILSRFVSIRNTKEN 561 +GG + SG + G L ++S++ Sbjct: 459 WGGIKRSGFGRELGEW-GLENYLSVKQVTRY 488 >3IWJ-A nrPDB Length = 503 Score = 488 bits (1256), Expect = e-138, Method: Composition-based stats. Identities = 137/512 (26%), Positives = 229/512 (44%), Gaps = 38/512 (7%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA-----KKDW 116 L ING+ P NPA Q ++ ++ AT++DV AV AAK A DW Sbjct: 9 QLFINGDW-KAPVLNKRIPVINPAT-QNIIGDIPAATKEDVDVAVAAAKTALTRNKGADW 66 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 R+ A + T+ + ++ + GK + +A D I +++ F YY Sbjct: 67 ATASGAVRARYLRAIAAKV-TEKKPELAKLESIDCGKPLDEAAWD-IDDVAGCFEYYADL 124 Query: 177 ASDLYAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTV-VW 233 A L A+Q PV T+ R G V ++P+N+ + A APAL + Sbjct: 125 AEKLDARQKAPVSLPMDTFKSHVLREPIGVVGLITPWNYPMLMATWKVAPALAAGCAAIL 184 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KPS+ A+L+ L + +E GLP GV+N + G + + D + FTGS+ Sbjct: 185 KPSELASLTCLELGEICKEVGLPPGVLNILTGLGPEAGAPLATHPDVDKVAFTGSSATG- 243 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 S ++ + + E GGK+ +V ++ A I G F GQ CSA Sbjct: 244 -------SKIMTAAAQLVKPVSLELGGKSPLVVFEDVDLDKAAEWAIFGCFWTNGQICSA 296 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 SRL L ES + EFL+ + +++ + + P+ G +GPV+ E ++K++K Sbjct: 297 TSRLILHESIATEFLNRIVKWIKNIKI------SDPLEEGCR---LGPVVSEGQYEKILK 347 Query: 414 VIEDAKKDPELEILYGGQYDK-SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 + +AK + + G + + +G+F+ PT+I + E FGP+L V + Sbjct: 348 FVSNAKSEGATILTGGSRPEHLKKGFFIEPTIITDVTTNMQIWREEVFGPVLCVKTFSTE 407 Query: 473 EFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFG 532 E E D + N + Y L A+ + D + E + F AG ++N C+ +Q +G Sbjct: 408 E--EAID-LANDTVYGLGAAVISNDLERCERVTKA--FKAGIVWVN--CSQPCFTQAPWG 460 Query: 533 GARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 G + SG + G L ++S++ + E Sbjct: 461 GVKRSGFGRELGEW-GLDNYLSVKQVTQYISE 491 >4MPY-A nrPDB Length = 520 Score = 487 bits (1253), Expect = e-138, Method: Composition-based stats. Identities = 131/504 (25%), Positives = 222/504 (44%), Gaps = 36/504 (7%) Query: 64 VINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKK--DWYNLPF 121 I+GE + N + NP N Q+V+ V++ T++D A+ AA+ A + +W Sbjct: 36 YIDGEWVESAN-KNTRDIINPYN-QEVIFTVSEGTKEDAERAILAARRAFESGEWSQETA 93 Query: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY 181 R AD I ++R + L GK + ++ D + ++ + F Y+ A Sbjct: 94 ETRGKKVRAIADKI-KEHREALARLETLDTGKTLEESYAD-MDDIHNVFMYFAGLADKDG 151 Query: 182 AQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAA 240 + T +K P+ G V ++P+N+ + A+ APAL G ++V KPS+ Sbjct: 152 GEMIDSPIPDTESKIVKEPV-GVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITP 210 Query: 241 LSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQ 300 L+ + ++EE G PKG IN I G +V D + K+ + FTG K + Sbjct: 211 LTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHI----- 265 Query: 301 SGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLP 360 ++ + I E GGKN +++ A+ AV + G + GQ CSA SR+ + Sbjct: 266 ---MKNAANNVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQ 322 Query: 361 ESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKK 420 S ++F + ++ + +G + MGPVI + +K+ ++ AK Sbjct: 323 NSIKDKFEQALIDRVKKIKLG---------NGFDADTEMGPVISTEHRNKIESYMDVAKA 373 Query: 421 DPELEILYGGQYDKS---QGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 + + G + D+ G F PTVI + E FGP++TV + E + Sbjct: 374 EGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGF---ETEQE 430 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 + N S Y L GA+F+KD + KLK G +IND +Q +GG + S Sbjct: 431 AIQLANDSIYGLAGAVFSKDIGKAQRVANKLKL--GTVWINDF--HPYFAQAPWGGYKQS 486 Query: 538 GTDDKAGGPNILSRFVSIRNTKEN 561 G + G L ++ ++ N Sbjct: 487 GIGRELGK-EGLEEYLVSKHILTN 509 >1BPW-A nrPDB Length = 503 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 126/509 (24%), Positives = 216/509 (42%), Gaps = 42/509 (8%) Query: 66 NGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRS 125 G RI + P PA +VL + ++V AV++A+ A W + +RS Sbjct: 25 GGRRIKSKDGATTEPVFEPATG-RVLCQMVPCGAEEVDQAVQSAQAAYLKWSKMAGIERS 83 Query: 126 AIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQP 185 + L+AA +I + R ++ ++ GK + +AE D I YY A L Q Sbjct: 84 RVMLEAARIIRER-RDNIAKLEVINNGKTITEAEYD-IDAAWQCIEYYAGLAPTLSGQH- 140 Query: 186 VESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNY 244 ++ G + PL G + +N+ + A APAL GN VV+KPS ++ Sbjct: 141 IQLPGGAFAYTRREPL-GVCAGILAWNYPFMIAAWKCAPALACGNAVVFKPSPMTPVTGV 199 Query: 245 LLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVV 304 +L + EAG+P G++N + G + + + + FTGS K V+ Sbjct: 200 ILAEIFHEAGVPVGLVNVVQG-GAETGSLLCHHPNVAKVSFTGSVPTGKK--------VM 250 Query: 305 EGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKS 364 E + + E GGK+ L+ + +AV + F QGQ C+ +R+++ Sbjct: 251 EMSAKTVKHVTLELGGKSPLLIFKDCELENAVRGALMANFLTQGQVCTNGTRVFVQREIM 310 Query: 365 EEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPEL 424 +FL ++ ++ V P+ MG +I + DK++ + AKK+ Sbjct: 311 PQFLEEVVKRTKAIVV------GDPLLTETR---MGGLISKPQLDKVLGFVAQAKKEGA- 360 Query: 425 EILYGGQ------YDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 +L GG+ G+F+ P V+ R D + E FGP+++V + E E+ Sbjct: 361 RVLCGGEPLTPSDPKLKNGYFMSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEE--EVL 418 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 +NT+ + L +F +D L+ AG YIN V + FGG +MSG Sbjct: 419 QRANNTT-FGLASGVFTRDISRAHRVAANLE--AGTCYINTYSISPV--EVPFGGYKMSG 473 Query: 539 TDDKAGGPNILSRFVSIRNTKENFYELTD 567 + G + + ++ E+ D Sbjct: 474 FGRENGQ-ATVDYYSQLKTV---IVEMGD 498 >3RHO-A nrPDB Length = 517 Score = 483 bits (1244), Expect = e-137, Method: Composition-based stats. Identities = 119/506 (23%), Positives = 209/506 (41%), Gaps = 31/506 (6%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD--W 116 + L I GE + D + NP + V+ V+ A DV AV AAK+A ++ W Sbjct: 35 MPYQLFIGGEFV-DAEGSKTYNTINPTDGS-VICQVSLAQVSDVDKAVAAAKEAFENGLW 92 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 + DR + + AD++ +++ ++ L G A + FRY+ + Sbjct: 93 GKINARDRGRLLYRLADVME-QHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGW 151 Query: 177 ASDLYAQQPV--ESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVW 233 + ++ + G V P+N+ + + A L GNTVV Sbjct: 152 CDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVI 211 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KP+Q L+ + +AG+PKGV+N +PG V ++ D + FTGST V K Sbjct: 212 KPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGK 271 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 + + ++ + GGK+ ++ +++ AV + F +G+ C A Sbjct: 272 HIMKSC-------ALSNVKKVSLQLGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIA 324 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 A RL++ ES +F+ + ++ + +P+ GP HE KLV+ Sbjct: 325 AGRLFVEESIHNQFVQKVVEEVEKMKI------GNPLERDTNH---GPQNHEAHLRKLVE 375 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 + K+ ++ GG G+F PTV E FGPI+ + + D + Sbjct: 376 YCQRGVKEGAT-LVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGD 434 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 + + N +++ L +F +D Y +KL+ AG +IN V + FGG Sbjct: 435 VDAVLSR-ANATEFGLASGVFTRDINKALYVSDKLQ--AGTVFINTYNKTDVAA--PFGG 489 Query: 534 ARMSGTDDKAGGPNILSRFVSIRNTK 559 + SG G L+ ++ I+ Sbjct: 490 FKQSGFGKDLGE-AALNEYLRIKTVT 514 >3JZ4-A nrPDB Length = 481 Score = 482 bits (1242), Expect = e-136, Method: Composition-based stats. Identities = 119/503 (23%), Positives = 212/503 (42%), Gaps = 32/503 (6%) Query: 55 KSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKK 114 S+ +INGE + NN A TNPAN + L +V + + A+ AA A Sbjct: 4 DSNLFRQQALINGEWLDANNGEA-IDVTNPANGDK-LGSVPKMGADETRAAIDAANRALP 61 Query: 115 DWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYV 174 W L +R+ I +L+ +++ D+ L QGK + +A+ + I+ + F ++ Sbjct: 62 AWRALTAKERATILRNWFNLM-MEHQDDLARLMTLEQGKPLAEAKGE-ISYAASFIEWFA 119 Query: 175 KYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVW 233 + +Y +P+ G A++P+NF A PAL G T+V Sbjct: 120 EEGKRIYGDTIPGHQADKRLIVIKQPI-GVTAAITPWNFPAAMITRKAGPALAAGCTMVL 178 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KP+ S L + AG+P GV N + G V +++ ++ L FTGST + + Sbjct: 179 KPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGR 238 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 L +E +D ++ E GG +V A++ AV + F GQ C Sbjct: 239 QL--------MEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVC 290 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 A+RLY+ + + F + + ++ + +GP+I E++ K+ + Sbjct: 291 ANRLYVQDGVYDRFAEKLQQAMSKLHIGDGLDNG---------VTIGPLIDEKAVAKVEE 341 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 I DA + ++ GG+ + G F PT++ + E FGP+ ++ + D Sbjct: 342 HIADALEKGA-RVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEA 400 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 N +++ L +A+D + E L++ G IN V+ FGG Sbjct: 401 D---VIAQANDTEFGLAAYFYARDLSRVFRVGEALEY--GIVGINTGIISNEVA--PFGG 453 Query: 534 ARMSGTDDKAGGPNILSRFVSIR 556 + SG + G + ++ I+ Sbjct: 454 IKASGLGRE-GSKYGIEDYLEIK 475 >3R31-A nrPDB Length = 517 Score = 477 bits (1227), Expect = e-135, Method: Composition-based stats. Identities = 119/502 (23%), Positives = 205/502 (40%), Gaps = 34/502 (6%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119 + I+G+ + DN F PA + ++A + AT V A+ +AK A+K+W + Sbjct: 14 KASHFIDGDYVEDNT-GTPFESIFPATGE-MIAKLHAATPAIVERAIASAKRAQKEWAAM 71 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 R I +AAD++ + + L GK + + + T +D F ++ A Sbjct: 72 SPMARGRILKRAADIMRERN-DALSTLETLDTGKPIQETIVADPTSGADAFEFFGGIAPS 130 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQT 238 + G + + PL G + +N+ A APAL GN +V+KPS+ Sbjct: 131 ALNGDYIPLG-GDFAYTKRVPL-GVCVGIGAWNYPQQIACWKAAPALVAGNAMVFKPSEN 188 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 L + +L EAGLPKG+ N I GD ++ D + TGS + Sbjct: 189 TPLGALKIAEILIEAGLPKGLFNVIQGDR-DTGPLLVNHPDVAKVSLTGSVPTGRK---- 243 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 V + E GGK+ +V A+I AV + G F GQ CS +R++ Sbjct: 244 ----VAAAAAGHLKHVTMELGGKSPMIVFDDADIESAVGGAMLGNFYSSGQVCSNGTRVF 299 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + + FL ++ ++ + + +GP++ + +K++ IE Sbjct: 300 VQKKAKARFLENLKRRTEAMILGDPL---------DYATHLGPLVSKAQQEKVLSYIEKG 350 Query: 419 KKDPELEILYGGQYD--KSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNE 476 K + I GG + +G +V PTV D E FGP++ V ++ D + Sbjct: 351 KAEGATLITGGGIPNNVAGEGAYVQPTVFADVTDDMTIAREEIFGPVMCVLDFDD---ED 407 Query: 477 ICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 536 N +++ L G +F D + L+ AG +IN V + FGG++ Sbjct: 408 EVLARANATEFGLAGGVFTADLARAHRVVDGLE--AGTLWINTYNLCPV--EIPFGGSKQ 463 Query: 537 SGTDDKAGGPNILSRFVSIRNT 558 SG + L + ++ Sbjct: 464 SGFGRE-NSAAALEHYSELKTV 484 >4IDS-A nrPDB Length = 563 Score = 476 bits (1224), Expect = e-134, Method: Composition-based stats. Identities = 245/543 (45%), Positives = 331/543 (60%), Gaps = 15/543 (2%) Query: 29 RNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQ 88 NEPV + + LR L +++P VI G + ER P H Sbjct: 31 ANEPVHDYAP-KSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGER--IDVVQPHRHA 87 Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATM 148 L +T AT D AV+AA AK DW LPF +R+A+FL+AADL++ +R + AATM Sbjct: 88 ARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATM 147 Query: 149 LGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAV 208 LGQ K+VYQAEID + EL DF+R+ V +A + QQP+ S G WN+ +YRPL+GFVYA+ Sbjct: 148 LGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPI-SGPGEWNRIDYRPLDGFVYAI 206 Query: 209 SPFNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPV 268 +PFNFT+IA NL APALMGNTV+WKPS T L+ YL M +LE AGLP GVIN + GD Sbjct: 207 TPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGF 266 Query: 269 QVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHP 328 V+D LAD +HFTGST F L+ + + + G+Y YPR++GETGGK+F + H Sbjct: 267 AVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNI--GRYHSYPRLVGETGGKDFVVAHA 324 Query: 329 SANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSAS 388 SA + IRG F++QGQKCSA SR ++ S + ++ + Sbjct: 325 SARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDIT---- 380 Query: 389 PISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAK 448 +L + G +I +++F K V IE AK + + GG+YD S+G+FV PTV+ + Sbjct: 381 -----DLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSD 435 Query: 449 RPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKL 508 P E+FGP+L+V+ YPD + +I D+ID S+YALTGA+ A DR+A+ A ++L Sbjct: 436 DPTDESFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRL 495 Query: 509 KFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELTDF 568 +F+AGNFY+NDK TGAVV +Q FGGAR S T+DKAG P L R+ S R+ KE F TD Sbjct: 496 RFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSIKETFVAATDH 555 Query: 569 KYP 571 YP Sbjct: 556 IYP 558 >6QAO-A nrPDB Length = 508 Score = 473 bits (1218), Expect = e-134, Method: Composition-based stats. Identities = 115/509 (22%), Positives = 217/509 (42%), Gaps = 42/509 (8%) Query: 66 NGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRS 125 G R+ + PA +V+A T + EK+V AV+ AK A K W +R Sbjct: 30 GGARVEPADASGTEKAFEPATG-RVIATFTCSGEKEVNLAVQNAKAAFKIWSQKSGMERC 88 Query: 126 AIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQP 185 I L+AA +I + ++ + GK++++A +D I YY A+ + + Sbjct: 89 RILLEAARIIRERE-DEIATMECINNGKSIFEARLD-IDISWQCLEYYAGLAASMAGEH- 145 Query: 186 VESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNY 244 ++ G++ PL G + +N+ A+ APAL GN +V+KPS +S Sbjct: 146 IQLPGGSFGYTRREPL-GVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSAL 204 Query: 245 LLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVV 304 LL + EAG+P G+ N + G + D + FTGS + + Sbjct: 205 LLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKI--------M 255 Query: 305 EGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKS 364 E + + E GGK+ ++ ++++AV + F QGQ C +R+++ + Sbjct: 256 EMSAKGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEIL 315 Query: 365 EEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPEL 424 ++F ++ Q + P+ MGP+I+ ++++ ++ AK+ Sbjct: 316 DKFTEEVVKQTQRIKI------GDPLLEDTR---MGPLINRPHLERVLGFVKVAKEQGA- 365 Query: 425 EILYGG------QYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 ++L GG G+++ P V+ R D + E FGP++++ + E+ Sbjct: 366 KVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEA--EVL 423 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + N + + L +F +D + +L+ AG +IN+ V + FGG + SG Sbjct: 424 ER-ANDTTFGLAAGVFTRDIQRAHRVVAELQ--AGTCFINNYNVSPV--ELPFGGYKKSG 478 Query: 539 TDDKAGGPNILSRFVSIRNTKENFYELTD 567 + G + + ++ E+ D Sbjct: 479 FGRENGRV-TIEYYSQLKTVC---VEMGD 503 >4I8P-A nrPDB Length = 520 Score = 471 bits (1213), Expect = e-133, Method: Composition-based stats. Identities = 137/522 (26%), Positives = 224/522 (42%), Gaps = 40/522 (7%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAA-----KDAKKDW 116 L ++GE R L P NP + + T +DV AV AA ++ +DW Sbjct: 26 QLFVDGEWRPPAQGRRL-PVVNPTTEAH-IGEIPAGTAEDVDAAVAAARAALKRNRGRDW 83 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 P R+ A + + + ++ L GK +A D + +++ F Y+ Sbjct: 84 ARAPGAVRAKYLRAIAAKVIER-KPELAKLEALDCGKPYDEAAWD-MDDVAGCFEYFADQ 141 Query: 177 ASDLYAQQ--PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVW 233 A L +Q PV T+ R G V ++P+N+ + A APAL G T V Sbjct: 142 AEALDKRQNSPVSLPMETFKCHLRREPIGVVGLITPWNYPLLMATWKIAPALAAGCTAVL 201 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KPS+ A+++ L + +E GLP GV+N + G + A D + FTGS K Sbjct: 202 KPSELASVTCLELADICKEVGLPSGVLNIVTGLGPDAGAPLSAHPDVDKVAFTGSFETGK 261 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 + V + E GGK+ +V +I AV T+ G F GQ CSA Sbjct: 262 KIMASAAPMV--------KPVTLELGGKSPIVVFDDVDIDKAVEWTLFGCFWTNGQICSA 313 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 SRL + +++F M ++ V + P+ G +GPV+ E ++K+ K Sbjct: 314 TSRLLIHTKIAKKFNERMVAWAKNIKV------SDPLEEGCR---LGPVVSEGQYEKIKK 364 Query: 414 VIEDAKKDPELEILYGGQYDK-SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 I +AK + G + +G+F+ PT+I E FGP+L V E+ Sbjct: 365 FISNAKSQGATILTGGVRPAHLEKGFFIEPTIITDITTSMEIWREEVFGPVLCVKEFSTE 424 Query: 473 EFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFG 532 +E + + N +QY L GA+ + DR+ + E + AG ++N C+ Q +G Sbjct: 425 --DEAIE-LANDTQYGLAGAVISGDRERCQRLSE--EIDAGCIWVN--CSQPCFCQAPWG 477 Query: 533 GARMSGTDDKAGGPNILSRFVSIRNTKENFY--ELTDFKYPS 572 G + SG + G + ++S++ E ++ PS Sbjct: 478 GNKRSGFGRELGE-GGIDNYLSVKQVTEYISDEPWGWYQSPS 518 >4I8Q-A nrPDB Length = 514 Score = 470 bits (1209), Expect = e-133, Method: Composition-based stats. Identities = 128/520 (24%), Positives = 226/520 (43%), Gaps = 40/520 (7%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA--KKDWYNL 119 L I GE + ++ P NPA ++++ ++ AT +DV AV+AA+ A + DW + Sbjct: 25 QLYIGGEW-REPVKKNRIPIINPAT-EEIIGDIPAATAEDVDIAVEAARKAIARDDWGST 82 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 R+ A + + + + L GK +Y++ D + +++ F YY A Sbjct: 83 TGAQRAKYLRAIAAKV-LEKKSVLATLESLDSGKTLYESAAD-MDDVAGCFEYYAGLAEA 140 Query: 180 LYAQ--QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMGNTV-VWKPS 236 L ++ PV ++ R G V ++P+N+ + A APAL + KPS Sbjct: 141 LDSRRMTPVNLNSDSYKSYVLREPLGVVGLITPWNYPLLMAIWKVAPALAAGCAAILKPS 200 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + A+++ L + E GLP G +N + G + + + + FTGS Sbjct: 201 ELASITCLELGEICREIGLPSGALNILTGLGPEAGGPLASHPHVDKISFTGSGPTG---- 256 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSAN-ISHAVLSTIRGTFEFQGQKCSAAS 355 S ++ + + GGK+ +V + + A T+ G F GQ CSA S Sbjct: 257 ----SKIMTAAAQLVKPVSLALGGKSPIVVFDDIDNLDIAAEWTLFGIFANTGQVCSATS 312 Query: 356 RLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415 RL + E+ + F+ + ++ + + P+ +GPV+ ++K++K I Sbjct: 313 RLIVQENIASAFMDRLLKWTKNIKI------SDPLEEDC---KLGPVVSAGQYEKVLKFI 363 Query: 416 EDAKKDPELEILYGGQYDK--SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 +AK + IL GG+ + +G++V PT+I E FGP+L V + E Sbjct: 364 SNAKSEGAT-ILCGGERPQHLKKGYYVQPTIITDVNTSMEIWKEEVFGPVLCVKTFKTEE 422 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 + N ++Y L A+ +KD K E + F G +IN C+ ++ +GG Sbjct: 423 Q---AIELANDTKYGLGAAVMSKDVKRCERFTKA--FQTGIIWIN--CSQPTFNELPWGG 475 Query: 534 ARMSGTDDKAGGPNILSRFVSIRNTKENFY--ELTDFKYP 571 + SG G L F++I+ E L +K P Sbjct: 476 KKRSGFGRDLGKW-GLENFLNIKQVTEYTSAEPLAFYKSP 514 >4GO4-A nrPDB Length = 495 Score = 468 bits (1205), Expect = e-132, Method: Composition-based stats. Identities = 131/505 (25%), Positives = 212/505 (41%), Gaps = 37/505 (7%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 ++ L I+G + D +P + ++ + A DV AV AAK A W Sbjct: 1 MQNQLYIDGRFV-DAVAGGTIDVVSPHDGS-LITRIAAAEAADVDLAVAAAKRAFPAWSA 58 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 L +R + LK AD I + ++ L G + + + + FRY+ A Sbjct: 59 LGAAERGRLLLKLADRIE-ECSEELAQLESLNTGHPIRDSRGLDVPRTAACFRYFGGMAD 117 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 + + G N + +P+ G V + P+NF + + PAL GNT+V KPS+ Sbjct: 118 KIEGSV-IPVDAGFLNYVQRKPI-GVVAQIVPWNFPLMFTSWKMGPALAAGNTIVIKPSE 175 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 LS ++ ++ E G PKGV+N +PG + D G + FTGST + + Sbjct: 176 ITPLSTLRIVELMTEVGFPKGVVNVVPGYGHTAGQALAEHLDVGKIAFTGSTATGRRI-- 233 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 VE + RI E GGK ++V ANI AV F QGQ C A SRL Sbjct: 234 ------VEASKSNLKRIQLELGGKGANIVFEDANIEAAVNGAAWAIFHNQGQACIAGSRL 287 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 L + +++FL + +S + + MGP+ D+++ I+ Sbjct: 288 ILHKDIADQFLERFIALAKSIRLGDP---------MDPETEMGPLTSALRRDRVLSYIDI 338 Query: 418 AKKDPELEILYGGQYDKSQ----GWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 A + ++L GG+ + G++V PTV++A +P E FGP +TV + Sbjct: 339 AIEQGG-KVLAGGKAPDDKALANGFYVEPTVVEA-KPQDRVCQEEVFGPFVTVVRFSS-- 394 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 +E I N ++Y L ++ ++ + AG +IN C V FGG Sbjct: 395 -DEEALAIANNTEYGLGSGLWTQNLARAHKMAHAI--HAGMCWIN--CYKRVSPGSPFGG 449 Query: 534 ARMSGTDDKAGGPNILSRFVSIRNT 558 SG + G + + R+ Sbjct: 450 VGQSGYGREMG-FEAIHDYTEARSV 473 >1WNB-A nrPDB Length = 495 Score = 464 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 125/513 (24%), Positives = 218/513 (42%), Gaps = 32/513 (6%) Query: 47 LRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAV 106 L ++ + K+ ++ L+INGE + E+ P NPA VL + +A+ + V AV Sbjct: 10 LESTSLYKKAGLMQHKLLINGELVSGEGEKQ--PVYNPATGD-VLLEIAEASAEQVDAAV 66 Query: 107 KAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITEL 166 +AA A +W R+ LK AD+I + GK ++ A D I + Sbjct: 67 RAADAAFAEWGQTTPKVRAECLLKLADVIEENGQV-FAELESRNCGKPLHSAFNDEIPAI 125 Query: 167 SDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL 226 D FR++ A L E +G + PL G V +++P+N+ + A APAL Sbjct: 126 VDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPL-GVVASIAPWNYPLMMAAWKLAPAL 184 Query: 227 M-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHF 285 GN VV KPS+ L+ L + ++ P GV+N + G V D + + Sbjct: 185 AAGNCVVLKPSEITPLTALKLAELAKDI-FPAGVVNILFGRGKTVGDPLTGHPKVRMVSL 243 Query: 286 TGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFE 345 TGS + + S + R E GGK +V A+I V + Sbjct: 244 TGSIATGEHIISHTASSI--------KRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYY 295 Query: 346 FQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHE 405 GQ C+AA R+Y + + + + + + + + +GP+ Sbjct: 296 NAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPD---------DESTELGPLSSL 346 Query: 406 QSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILT 465 +++ K +E+AK ++++ GG+ K G++ PT++ D + E FGP+++ Sbjct: 347 AHLERVGKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVS 406 Query: 466 VYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAV 525 V + + E N SQY L +++ KD +L++ G ++N + Sbjct: 407 VTPFDNEEQ---VVNWANDSQYGLASSVWTKDVGRAHRVSARLQY--GCTWVNTHFM--L 459 Query: 526 VSQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 VS+ GG ++SG K L + +R+ Sbjct: 460 VSEMPHGGQKLSGYG-KDMSLYGLEDYTVVRHV 491 >4O5H-A nrPDB Length = 511 Score = 462 bits (1190), Expect = e-130, Method: Composition-based stats. Identities = 133/527 (25%), Positives = 214/527 (40%), Gaps = 44/527 (8%) Query: 45 DLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMN 104 D RA L K K ++I E D NPA+ V+A V +A E+DV Sbjct: 21 DATRAFLAKPK------QMLIGAEW-SDAASGRQLDVVNPADGT-VIARVPEADERDVQQ 72 Query: 105 AVKAAKDAK--KDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDC 162 AV AA+ A W DR + L ADLI R ++ L GK V A+ Sbjct: 73 AVAAARRAFDAGPWRTAKTTDRERLMLVLADLIEANAR-ELAEIESLDNGKPVMVAQGLD 131 Query: 163 ITELSDFFRYYVKYASDLYA-----QQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIA 217 + + FRY +A+ + P + P+ G V A+ P+NF + Sbjct: 132 VAMAAQCFRYMAGWATKIEGSVIDAGMPYLPDSEIFAYTRKEPV-GVVGAIIPWNFPLLM 190 Query: 218 ANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLA 276 A APAL G TVV KP++ LS L +++ AG P GV+N + G + Sbjct: 191 AAWKIAPALATGCTVVLKPAEDTPLSALRLGELIQAAGFPDGVVNIVTGYGHTAGAALSR 250 Query: 277 DKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAV 336 D + FTGST K++ + R+ E GGK+ +V P ++ A Sbjct: 251 DPRIDKIAFTGSTQTGKTI--------GHAALDNMTRMSLELGGKSPVIVLPDVDLDKAA 302 Query: 337 LSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLR 396 F QGQ C+A SR Y+ + + + I S + P G + Sbjct: 303 QGVANAIFFNQGQVCTAGSRAYIHSKVFDGVIERVAKIAASLKIGP---------GMDPA 353 Query: 397 GFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMS 456 +GP++ + +++ I+ + G+ G+FV PTV+ + Sbjct: 354 TQIGPLVSAKQRERVCGYIDSGFGEGARAAAG-GRAIDGPGFFVEPTVLVDTTQAMRVVR 412 Query: 457 TEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFY 516 E FGP+L + D + + N + Y L +I++ D AI + +AG + Sbjct: 413 EEIFGPVLVAMPFDDV---DTAVQLANDTPYGLGASIWSNDLSAIHKLVP--RIAAGTVW 467 Query: 517 INDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFY 563 +N C + + FGG + SG + G ++ ++ ++ N+ Sbjct: 468 VN--CHSLLDNALPFGGMKQSGFGRELGR-AVIDQYTESKSVMMNYA 511 >2D4E-A nrPDB Length = 515 Score = 461 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 126/529 (23%), Positives = 219/529 (41%), Gaps = 41/529 (7%) Query: 44 WDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVM 103 W+ + + K I GE + + FP +PA ++ VL + E++V Sbjct: 12 WETIEEVRRRLKERPAL--HFIAGEFVPSES-GETFPSLDPATNE-VLGVAARGGEREVD 67 Query: 104 NAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCI 163 A KAA +A + W +R L+ A+LI K+ ++ L G+ + + Sbjct: 68 RAAKAAHEAFQRWSRTKAKERKRYLLRIAELIE-KHADELAVMECLDAGQVLRIVRA-QV 125 Query: 164 TELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGA 223 ++ F +Y +YA + D W R G V ++P+N + + A Sbjct: 126 ARAAENFAFYAEYAEHAMEDRTFPV-DRDWLYYTVRVPAGPVGIITPWNAPLMLSTWRIA 184 Query: 224 PALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGA 282 PAL GNTVV KP++ + + L +L+EA LP GV N + G + ++A Sbjct: 185 PALAFGNTVVLKPAEWSPFTATKLAEILKEADLPPGVFNLVQGFGEEAGAALVAHPLVPL 244 Query: 283 LHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRG 342 L TG T K V+ R+ E GGK+ LV A++ A+ + + Sbjct: 245 LTLTGETETGK--------IVMRNAADHLKRLSPELGGKSPALVFADADLERALDAVVFQ 296 Query: 343 TFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPV 402 F F G++C+A+SRL + E E+F+ + ++ V + +GP+ Sbjct: 297 IFSFNGERCTASSRLLVEEKIFEDFVGKVVERARAIRVG---------HPLDPETEVGPL 347 Query: 403 IHEQSFDKLVKVIEDAKKDPELEILYGGQY-------DKSQGWFVGPTVIKAKRPDHPYM 455 IH + +++ +E K++ ++ G + D S+G ++ PTV + Sbjct: 348 IHPEHLQRVLGYVEAGKREGARLLVGGERAKTSFRGEDLSRGNYLLPTVFVGENH-MKIA 406 Query: 456 STEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNF 515 E FGP+L + D E N ++Y L +F +D + L+ AG Sbjct: 407 QEEIFGPVLVAIPFKD---EEEALRKANDTKYGLAAYVFTRDLERAHRLA--LELEAGMV 461 Query: 516 YINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 Y+N + + FGG + SG D + GG L + ++ Sbjct: 462 YLNSHNVRHLPT--PFGGVKGSG-DRREGGTYALDFYTDLKTIALPLRP 507 >6C43-A nrPDB Length = 477 Score = 460 bits (1184), Expect = e-130, Method: Composition-based stats. Identities = 114/504 (22%), Positives = 208/504 (41%), Gaps = 32/504 (6%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 S++++ L+ING + ER NPA + V+ + +A+ V AV+AA +A + Sbjct: 1 SNAMQYQLLINGVLVDGEGERQS--VYNPATGE-VILEIAEASPAQVDAAVQAADNAFAE 57 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W R+ LK AD I + GK ++ D I + D FR++ Sbjct: 58 WGQTTPKARAECLLKLADSIEQNA-LEFARLESQNCGKPLHCVINDEIPAIVDVFRFFAG 116 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWK 234 A L E +G + P+ G V +++P+N+ + A APAL GN VV K Sbjct: 117 AARCLSGLAAGEYLEGHTSMIRRDPI-GVVASIAPWNYPLMMAAWKLAPALAAGNCVVIK 175 Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKS 294 PS+ L+ L + ++ P GV+N + G V D + + + TGS + Sbjct: 176 PSEITPLTALKLAVLAKDI-FPPGVLNVLFGRGQTVGDVLTGHEKVRMVSLTGSIATGEH 234 Query: 295 LYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAA 354 + + R E GGK +V A++ F GQ C+AA Sbjct: 235 ILRHTAPAI--------KRTHMELGGKAPVIVFDDADLDAVAQGVRTFGFYNAGQDCTAA 286 Query: 355 SRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKV 414 R+Y + + + + S + + + +GP+ ++ Sbjct: 287 CRIYAQRGIYDALVEKLGNAVSSLKMG---------APEDESTELGPLSSLAHLKRVTAA 337 Query: 415 IEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEF 474 +E+AK + ++ GG + +G++ PT++ + + + E FGP++++ + D + Sbjct: 338 VEEAKALSHIRVITGGSQTEGKGYYFAPTLLADAKQEDAIVQREVFGPVVSITVFDDEDQ 397 Query: 475 NEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGA 534 N S+Y L +++ +D +L++ G +IN +VS+ GG Sbjct: 398 ---VLRWANDSRYGLASSVWTQDVGRAHRLSARLQY--GCTWINTHFM--LVSEMPHGGQ 450 Query: 535 RMSGTDDKAGGPNILSRFVSIRNT 558 + SG K L + +R+ Sbjct: 451 KQSGYG-KDMSLYGLEDYTLVRHI 473 >6B4R-B nrPDB Length = 497 Score = 458 bits (1178), Expect = e-129, Method: Composition-based stats. Identities = 123/521 (23%), Positives = 216/521 (41%), Gaps = 40/521 (7%) Query: 43 DWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDV 102 DW+ RA +K + + +NGE + F +P + + LA V D Sbjct: 8 DWEA-RAKDLKIEGRA-----FVNGEY-SNAASGETFDCLSPVDG-RFLAKVASCDLADA 59 Query: 103 MNAVKAAKDAK--KDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEI 160 AVK A++A W L R ++ ADL+ + ++ L GK + + Sbjct: 60 EQAVKVARNAFDSGAWSRLAPAKRKQTMIRFADLL-LENAEELALLETLDMGKPISDSLH 118 Query: 161 DCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANL 220 + ++ R+ + +Y + + P+ G V A+ P+NF + + Sbjct: 119 IDVASAANSLRWSAEAIDKIY-DEVAATPHAELGLVTREPV-GVVAAIVPWNFPLLMSCW 176 Query: 221 IGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKD 279 PAL GN+V+ KPS+ + L+ + + EAG+PKGV N +PG V + D Sbjct: 177 KLGPALATGNSVILKPSEKSPLTAIRIAQLAVEAGIPKGVFNVLPGYGHTVGKALALHMD 236 Query: 280 FGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA-NISHAVLS 338 L FTGST + K L V + R+ E GGK+ ++V A ++ A + Sbjct: 237 VDTLVFTGSTKIAKQLM-------VYAGESNMKRVWLEAGGKSPNIVFADAPDLKAAAEA 289 Query: 339 TIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGF 398 QG+ C+A SRL + S ++FL + L+ P + + Sbjct: 290 AAGAIAFNQGEVCTAGSRLLVERSIKDKFLPLVIEALKGWK---------PGNPLDPETN 340 Query: 399 MGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQY-DKSQGWFVGPTVIKAKRPDHPYMST 457 +G ++ Q + ++ IE D + G + +++ G +V PT+ Sbjct: 341 VGALVDTQQMNTVLSYIEAGHNDGAKLVAGGKRTLEETGGTYVEPTIFDGVTNAMKIARE 400 Query: 458 EFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYI 517 E FGP+L+V E+ D E I N + Y L A++ + + L+ AG+ ++ Sbjct: 401 EIFGPVLSVIEFED---AEEAVRIANDTPYGLAAAVWTSNLSKAHLTAKALR--AGSVWV 455 Query: 518 NDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 N G + + FGG + SG + ++ ++ T Sbjct: 456 NQYDGGDMTA--PFGGFKQSGNGRDK-SLHAFDKYTELKAT 493 >4F3X-A nrPDB Length = 498 Score = 457 bits (1177), Expect = e-129, Method: Composition-based stats. Identities = 118/507 (23%), Positives = 212/507 (41%), Gaps = 32/507 (6%) Query: 57 SSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDW 116 S ++ L+I + A NP ++ ++ +A+ + AV AA+ A W Sbjct: 22 SMMDTQLLIGSRF--EAGTEAEEHILNPRTGAGII-DLAEASHAQIDAAVDAAERAFVGW 78 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 +RS LK AD I + + A L GK + + D + + D +R++ Sbjct: 79 SQTTPAERSNALLKIADAIEKEA-DEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGA 137 Query: 177 ASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALMG-NTVVWKP 235 +L+A E G + P+ G V +++P+N+ + APA+ G NTVV+KP Sbjct: 138 VRNLHAPAAGEYLPGHTSMIRRDPI-GIVGSIAPWNYPLMMMAWKLAPAIGGGNTVVFKP 196 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 S+ L+ L ++ + LP+GV+N I G V + ++ G + TG K Sbjct: 197 SEQTPLTALKLARLIADI-LPEGVVNVITGRGETVGNALINHPKVGMVSITGDIATGKK- 254 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAAS 355 V+ + R E GGK +V+ A++ V + GQ C+AA Sbjct: 255 -------VLAAAAKTVKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAAC 307 Query: 356 RLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415 R+Y E+ ++D+ + + + +GP+I + D++ + Sbjct: 308 RIYAEAGIYEKLVADLTSAVSTIRY---------NLDDDTENEIGPLISRRQRDRVASFV 358 Query: 416 EDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 E A +EI GG+ +G+F PTV+ + + E FGP+++V + + Sbjct: 359 ERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDD- 417 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 N S Y L +++ KD A +L++ G +IN + ++ GG + Sbjct: 418 --AVAWANDSDYGLASSVWTKDISKAMRAASRLQY--GCTWINTHFM--LTNEMPHGGIK 471 Query: 536 MSGTDDKAGGPNILSRFVSIRNTKENF 562 SG K L + ++R+ N Sbjct: 472 QSGYG-KDMSVYALEDYTAVRHIMINH 497 >5J77-A nrPDB Length = 508 Score = 457 bits (1176), Expect = e-129, Method: Composition-based stats. Identities = 138/506 (27%), Positives = 233/506 (46%), Gaps = 39/506 (7%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 ++ L I+G+ + +++ + +P Q V+ + AT DV A+ AA+DA W + Sbjct: 1 MDTKLYIDGQWV-NSSSGKTVDKYSPVTGQ-VIGRMEAATRDDVDRAIDAAEDAFWAWND 58 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 L +RS I +A +LI K R ++ M GK V +A+ + + + D +YY ++A Sbjct: 59 LGSVERSKIIYRAKELIE-KNRAELENIIMEENGKPVKEAK-EEVDGVIDQIQYYAEWAR 116 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQ 237 L + VE +Y+ G V A++P+NF A APAL GNTVV KPS Sbjct: 117 KLNGEV-VEGTSSHRKIFQYKVPYGIVVALTPWNFPAGMVARKLAPALLTGNTVVLKPSS 175 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 S ++ EAG+PKGV+NFI G ++ D ++ K + TGST + + Sbjct: 176 DTPGSAEWIVRKFVEAGVPKGVLNFITGRGSEIGDYIVEHKKVNLITMTGSTATGQRIMQ 235 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 K + + ++I E GGK +V A++ +A+ + + + GQ C AA RL Sbjct: 236 KASANMA--------KLILELGGKAPFMVWKDADMDNALKTLLWAKYWNAGQSCIAAERL 287 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 Y+ E + F+S + + + MGP+I++ + +++E+ Sbjct: 288 YVHEDIYDTFMSRFVELSRKLALGDPKN-----------ADMGPLINKGALQATSEIVEE 336 Query: 418 AKKDPELEILYGGQYDK-----SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 AK+ +IL+GG G+F PT+I E F P++ + Sbjct: 337 AKESGA-KILFGGSQPSLSGPYRNGYFFLPTIIGNADQKSKIFQEEIFAPVIGARKISSV 395 Query: 473 EFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFG 532 E + N ++Y L +F KD I A E+++F G Y+N G SQ + Sbjct: 396 ---EEMYDLANDNKYGLASYLFTKDPNIIFEASERIRF--GELYVN--MPGPEASQGYHT 448 Query: 533 GARMSGTDDKAGGPNILSRFVSIRNT 558 G RM+G + G +S ++ ++N Sbjct: 449 GFRMTGQAGE-GSKYGISEYLKLKNI 473 >2J5N-A nrPDB Length = 516 Score = 456 bits (1174), Expect = e-128, Method: Composition-based stats. Identities = 168/539 (31%), Positives = 267/539 (49%), Gaps = 32/539 (5%) Query: 28 IRNEPVKPFRNIDLKDWDLLRASLMKFKSS-SLEVPLVINGERIYDNNERALFPQTNPAN 86 RNEP++ F+ + + +R +L + + PL I GE + D ER + NP+ Sbjct: 6 FRNEPIETFQTEEARR--AMREALRRVREEFGRHYPLYIGGEWV-DTKERMV--SLNPSA 60 Query: 87 HQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAA 146 +V+ +A + + A++AA A K W + P DRS + LKAA L+ + R ++ A Sbjct: 61 PSEVVGTTAKAGKAEAEAALEAAWKAFKTWKDWPQEDRSRLLLKAAALMRRRKR-ELEAT 119 Query: 147 TMLGQGKNVYQAEIDCITELSDFFRYYVKYASD-LYAQQPVESADGTWNKAEYRPL-EGF 204 + GKN +A D + E DF YY + A Y V G N++ Y PL G Sbjct: 120 LVYEVGKNWVEASAD-VAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYVPLGAGV 178 Query: 205 VYAVSPFNFTA-IAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFI 263 V ++P+NF I +I P +GNTV+ KP++ A + + + EAG P GV+NF+ Sbjct: 179 V--IAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFL 236 Query: 264 PGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNF 323 PG +V ++ ++FTGS V +Y +G + + R ETGGK+ Sbjct: 237 PGVGEEVGAYLVEHPRIRFINFTGSLEVGLKIYE--AAGRLAPGQTWFKRAYVETGGKDA 294 Query: 324 HLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPM 383 +V +A+ A + + FQGQKCSAASRL L + E L + + +V P Sbjct: 295 IIVDETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVGPA 354 Query: 384 NTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPT 443 + +GPV+ + K++ IE K + +++ GG+ + +G+F+ PT Sbjct: 355 EENPD----------LGPVVSAEQERKVLSYIEIGKNEG--QLVLGGKRLEGEGYFIAPT 402 Query: 444 VIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEY 503 V P E FGP+L+V D F E + + N + Y LTG ++++ R+ +E+ Sbjct: 403 VFTEVPPKARIAQEEIFGPVLSVIRVKD--FAEALE-VANDTPYGLTGGVYSRKREHLEW 459 Query: 504 ADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENF 562 A +F GN Y N K TGA+V Q FGG ++SGT+ K G + L F+ ++ E F Sbjct: 460 ARR--EFHVGNLYFNRKITGALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMKAVAERF 516 >5IUV-A nrPDB Length = 497 Score = 451 bits (1160), Expect = e-127, Method: Composition-based stats. Identities = 122/521 (23%), Positives = 208/521 (39%), Gaps = 40/521 (7%) Query: 43 DWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDV 102 DW+ RA +K + + I GE F +P + ++LA V D Sbjct: 8 DWEQ-RAQNLKIEGRA-----FIQGEY-TAAASGETFDCISPVDG-RLLAKVASCDAADA 59 Query: 103 MNAVKAAKDAK--KDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEI 160 AV++A+ A W L R A ++ A L+ ++ L GK + + Sbjct: 60 QRAVESARSAFDSGAWSRLAPAKRKATMIRFAGLLEQNA-EELALLETLDMGKPISDSLG 118 Query: 161 DCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANL 220 I + + + LY + + P+ G V A+ P+NF + A Sbjct: 119 VDIPGGARALSWSGEAIDKLY-DEVAATPHDQLGLVTREPV-GVVAAIVPWNFPLMMACW 176 Query: 221 IGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKD 279 PAL GN+VV KPS+ + L+ + + EAG+P GV+N +PG V + D Sbjct: 177 KLGPALSTGNSVVLKPSEKSPLTAIRIAQLAIEAGIPAGVLNVLPGYGHTVGKALALHMD 236 Query: 280 FGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA-NISHAVLS 338 + FTGST + K L + + R+ E GGK+ ++V A ++ A S Sbjct: 237 VDTVVFTGSTKIAKQLM-------IYAGESNMKRVWLEAGGKSPNIVFADAPDLQAAADS 289 Query: 339 TIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGF 398 QG+ C+A SRL + S + FL + L + P + + Sbjct: 290 AASAIAFNQGEVCTAGSRLLVERSIKDRFLPMVIEALGTWK---------PGNPLDPATN 340 Query: 399 MGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYD-KSQGWFVGPTVIKAKRPDHPYMST 457 +G ++ Q + ++ I D + G Q ++ G +V PT+ Sbjct: 341 VGALVDTQQMNTVLSYIAAGHTDGARLVAGGKQILQETGGTYVEPTIFDGVNNAMRIAQE 400 Query: 458 EFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYI 517 E FGP+L+V + E E I N + Y L A++ + L+ AG+ ++ Sbjct: 401 EIFGPVLSVLTFDTAE--EAIQ-IANDTPYGLAAAVWTANLSKAHLTARALR--AGSVWV 455 Query: 518 NDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 N G + + FGG + SG + ++ +++T Sbjct: 456 NQYDGGDMTA--PFGGFKQSGNGRDK-SLHAFDKYTELKST 493 >4V6H-A nrPDB Length = 484 Score = 450 bits (1157), Expect = e-126, Method: Composition-based stats. Identities = 115/499 (23%), Positives = 204/499 (40%), Gaps = 32/499 (6%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 L I GE + A F +PA + L V + + A++AA+ A W Sbjct: 11 LRHQAYIGGEW-QAADSDATFEVFDPATGES-LGTVPKMGAAETARAIEAAQAAWAGWRM 68 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 +R+AI + DL+ D+ QGK + +A+ + I + F ++ + Sbjct: 69 KTAKERAAILRRWFDLVIANS-DDLALILTTEQGKPLAEAKGE-IAYAASFIEWFAEEGK 126 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 + + + D + G A++P+NF A PAL G +V KP++ Sbjct: 127 RVAGDT-LPTPDANKRIVVVKEPIGVCAAITPWNFPAAMIARKVGPALAAGCPIVVKPAE 185 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 + S + + E AG+PKGV++ + GDP + ++ ++ L FTGST V + L Sbjct: 186 STPFSALAMAFLAERAGVPKGVLSVVIGDPKAIGTEITSNPIVRKLSFTGSTAVGRLLMA 245 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 + V ++ E GG +V A++ AV I + GQ C +R Sbjct: 246 QSAPTV--------KKLTLELGGNAPFIVFDDADLDAAVEGAIASKYRNNGQTCVCTNRF 297 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 ++ E + F + + V S +GP+I+E + K+ I D Sbjct: 298 FVHERVYDAFADKLAAAVSKLKVGRGTESG---------ATLGPLINEAAVKKVESHIAD 348 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 A + G ++ G+F PTV+ +PD E FGP+ ++ + E Sbjct: 349 ALAKGASLMTGGKRHALGHGFF-EPTVLTGVKPDMDVAKEETFGPLAPLFRFAS---EEE 404 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 + N +++ L ++++D + E L++ G IN V+ FGG + S Sbjct: 405 LVRLANDTEFGLAAYLYSRDIGRVWRVAEALEY--GMVGINTGLISNEVA--PFGGVKQS 460 Query: 538 GTDDKAGGPNILSRFVSIR 556 G + G + +V I+ Sbjct: 461 GLGRE-GSHYGIDDYVVIK 478 >5KLK-A nrPDB Length = 520 Score = 449 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 131/515 (25%), Positives = 219/515 (42%), Gaps = 41/515 (7%) Query: 54 FKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK 113 S+ ++ I+G + + F NP N +++++V +A K V AV AA++A Sbjct: 33 IGSAPSQLLNYIDGNFVTSASS---FANINPVNG-KLISDVFEADAKQVNEAVVAAQNAL 88 Query: 114 K-DWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRY 172 K W L DR+A+ K AD I ++ + +AA + G+ V+QA I FR Sbjct: 89 KGPWGKLSVQDRAALIHKIADGIQARF-EEFVAAEVADTGRPVHQARTLDIPRAIANFRT 147 Query: 173 YVKYASDLYA---QQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MG 228 + A + + G N +PL G + +SP++ + APAL G Sbjct: 148 FADLAKTSHTDLFEMSTSDGSGALNYTVRKPL-GVIGVISPWDLPLLLFTWKVAPALACG 206 Query: 229 NTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQ-VTDQVLADKDFGALHFTG 287 NTVV KPS+ + S LL V+ +AG+P GV N I G + + AL FTG Sbjct: 207 NTVVAKPSEESPSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTG 266 Query: 288 STNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQ 347 + ++ + GV + E GGKN +V A++ A+ +R +F Sbjct: 267 ESKTGSTIMKAVADGV--------KEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNS 318 Query: 348 GQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQS 407 GQ C + R+Y+ S +EF+S + + V + MGP+I Sbjct: 319 GQVCLCSERVYVHRSIFDEFVSGLKVEAERLVVGYPDQDG---------VNMGPLISHGH 369 Query: 408 FDKLVKVIEDAKKDPELEILYGGQY----DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI 463 DK++ A + + GG ++ QG +V PT+ ++ E FGP+ Sbjct: 370 RDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQGAYVQPTIWTGLSDKARCVTEEIFGPV 429 Query: 464 LTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTG 523 + + D +E+ + + N S Y L AI+ + + G ++N Sbjct: 430 CHISPFDDE--DEVINRV-NDSNYGLACAIWTTNLSRAHRVSR--QIHVGLVWVNTWYLR 484 Query: 524 AVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 + + FGG ++SG + GG + + I N Sbjct: 485 DL--RTPFGGVKLSGLGRE-GGRFSMDFYSDIANI 516 >2HG2-A nrPDB Length = 479 Score = 448 bits (1152), Expect = e-126, Method: Composition-based stats. Identities = 114/504 (22%), Positives = 225/504 (44%), Gaps = 31/504 (6%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 S ++ P+ I+G+ + + A NPA + V++ + +D A+ AA+ A+ + Sbjct: 2 SVPVQHPMYIDGQFVTWRGD-AWIDVVNPAT-EAVISRIPDGQAEDARKAIDAAERAQPE 59 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W LP +R++ K + I + R ++A ++ +G + Q + +D+ Y + Sbjct: 60 WEALPAIERASWLRKISAGI--RERASEISALIVEEGGKIQQLAEVEVAFTADYIDYMAE 117 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWK 234 +A + G N ++ G + P+NF APAL GNT+V K Sbjct: 118 WARRYEGEIIQSDRPGE-NILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIK 176 Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKS 294 PS+ + +++E GLP+GV N + G V ++ + + TGS + + Sbjct: 177 PSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEK 236 Query: 295 LYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAA 354 + + ++ ++ E GGK +V A++ AV + + GQ C+ A Sbjct: 237 I--------MATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCA 288 Query: 355 SRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKV 414 R+Y+ + ++F++ + +Q+ +P ++ MGP+I+ + +++ + Sbjct: 289 ERVYVQKGIYDQFVNRLGEAMQAVQ------FGNPAERNDIA--MGPLINAAALERVEQK 340 Query: 415 IEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEF 474 + A ++ + +GG+ + +G++ PT++ R + M E FGP+L V + E Sbjct: 341 VARAVEEGA-RVAFGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLED 399 Query: 475 NEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGA 534 + N S Y LT +I+ ++ A + LKF G YIN + A+ Q + G Sbjct: 400 ---AISMANDSDYGLTSSIYTQNLNVAMKAIKGLKF--GETYINRENFEAM--QGFHAGW 452 Query: 535 RMSGTDDKAGGPNILSRFVSIRNT 558 R SG G + L ++ + Sbjct: 453 RKSGIGGADGK-HGLHEYLQTQVV 475 >3I44-A nrPDB Length = 497 Score = 439 bits (1130), Expect = e-123, Method: Composition-based stats. Identities = 115/501 (22%), Positives = 208/501 (41%), Gaps = 35/501 (6%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPF 121 ING D + +P+ ++ A ++ + +D A+ AAK A + W Sbjct: 27 KFYINGLW-DDPSTPHDLYVIDPST-EEACAVISLGSTRDADKAINAAKKAFQTWKTTSP 84 Query: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY 181 ++R K ++ + DM + G + A S R ++K + Sbjct: 85 HERLGFVEKILEIYEKRS-SDMAKTISMEMGAPIDMALNAQTATGSSHIRNFIKAYKEFS 143 Query: 182 AQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAA 240 Q+ + +G + G V ++P+N+ L PAL G T+V KPS+ A Sbjct: 144 FQEAL--IEGNEQAILHYDAIGVVGLITPWNWPMNQVTLKVIPALLAGCTMVLKPSEIAP 201 Query: 241 LSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQ 300 LS L +L+EA LP GV N I GD V + A D + FTGST K + Sbjct: 202 LSAMLFAEILDEAALPSGVFNLINGDGANVGSYLSAHPDLEMISFTGSTRAGKDI----- 256 Query: 301 SGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLP 360 + R+ E GGK +++ A+I A+ +R F GQ C+A +R+ + Sbjct: 257 ---SKNASNTLKRVCLELGGKGANIIFADADID-ALQRGVRHCFYNSGQSCNAPTRMLVE 312 Query: 361 ESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKK 420 ++ ++ + I + V P + + + +GPV+ ++ +DK+ +I+ Sbjct: 313 QAIYDKAIKTAKDIAEKTQVGPGHQTGN---------HIGPVVSKEQYDKIQDLIQSGID 363 Query: 421 DPELEILYGGQYDKS--QGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 + + G +G++V PTV +P E FGP+L++ + + Sbjct: 364 EGATLVTGGTGLPMGMERGYYVRPTVFADVKPHMRIFREEIFGPVLSLLPFNT---EDEA 420 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + N ++Y LT I ++DR +++ +G +N + +FGG + SG Sbjct: 421 VTLANDTEYGLTNYIQSQDRSKCRRIAAQVR--SGMVEVNG---HELPGGSYFGGVKFSG 475 Query: 539 TDDKAGGPNILSRFVSIRNTK 559 + GG + F+ + Sbjct: 476 RARE-GGLWGIKEFLDTKAIS 495 >3EK1-A nrPDB Length = 504 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 114/511 (22%), Positives = 206/511 (40%), Gaps = 35/511 (6%) Query: 50 SLMKFKSSSL-EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKA 108 S++ K SL + ++NG I D + TNPA+ V+ V + + A+ A Sbjct: 21 SMLALKDPSLLKSQCLVNGRWI-DAADGTTIKVTNPADGS-VIGTVPSLSVATIKEAIDA 78 Query: 109 AKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSD 168 + A W +R+ I K DLI D+ QGK + +A + + + Sbjct: 79 SAKALSGWAAKTAKERAGILRKWFDLIIANA-DDIALIMTSEQGKPLAEARGE-VLYAAS 136 Query: 169 FFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-M 227 F ++ + A +Y +G +P+ G A++P+NF A APAL Sbjct: 137 FIEWFAEEAKRVYGDTIPAPQNGQRLTVIRQPV-GVTAAITPWNFPAAMITRKAAPALAA 195 Query: 228 GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTG 287 G T++ +P+ L+ L + E+AG+P GV+ + G ++ ++ ++ L FTG Sbjct: 196 GCTMIVRPADLTPLTALALGVLAEKAGIPAGVLQIVTGKAREIGAELTSNDTVRKLSFTG 255 Query: 288 STNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQ 347 ST V + L + + RI E GG +V A++ AV + + Sbjct: 256 STEVGRLLMAQCAPTI--------KRISLELGGNAPFIVFDDADLDAAVDGAMVSKYRNA 307 Query: 348 GQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQS 407 GQ C A+R+Y+ ++F + ++ V +GP+I E++ Sbjct: 308 GQTCVCANRIYVQRGVYDKFAEKLAAKVKELKVGNGTEPG---------VVIGPMIEEKA 358 Query: 408 FDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVY 467 K+ IEDA +++ GG+ + G F P ++ D E FGP+ ++ Sbjct: 359 ITKVKAHIEDAVSKGA-KLITGGK--ELGGLFFEPGILTGVTSDMLVAKEETFGPLAPLF 415 Query: 468 EYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVS 527 + E N + + L + ++ E L++ G N V+ Sbjct: 416 AFDT---EEEVIAQANDTIFGLAAYFYTENFSRAIRVSEALEY--GMVGHNTGLISNEVA 470 Query: 528 QQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 FGG + SG + G + ++ + Sbjct: 471 --PFGGVKQSGLGRE-GSKYGIEEYLETKYI 498 >3TY7-A nrPDB Length = 478 Score = 432 bits (1111), Expect = e-121, Method: Composition-based stats. Identities = 117/504 (23%), Positives = 208/504 (41%), Gaps = 40/504 (7%) Query: 64 VINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYD 123 INGE + ++N NPA ++V+ V + + DV AV+AA D ++ + + Sbjct: 11 YINGEWV-ESNSNETIEVINPAT-EEVIGKVAKGNKADVDKAVEAADDVYLEFRHTSVKE 68 Query: 124 RSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQ 183 R A+ K + + D++ A G + +E + F + A D Y Sbjct: 69 RQALLDKIVKEYENR-KDDIVQAITDELGAPLSLSERVHYQMGLNHF-VAARDALDNYEF 126 Query: 184 QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPA-LMGNTVVWKPSQTAALS 242 + D + G ++P+NF +L A A G+ VV KPS+ + Sbjct: 127 EERRGDD-----LVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKPSEETPFA 181 Query: 243 NYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSG 302 +L + ++ G+PKGV N + GD V + + + FTGS S Sbjct: 182 AVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTG--------SK 233 Query: 303 VVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPES 362 ++E +D+ ++ E GGK+ ++V +I A +T GQ C+A +R+ +P Sbjct: 234 IMEKAAKDFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNK 293 Query: 363 KSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDP 422 + FL+++ V +GP+I ++ FD++ I ++ Sbjct: 294 IKDAFLAELKEQFSQVRVGNPREDG---------TQVGPIISKKQFDQVQNYINKGIEEG 344 Query: 423 ELEILYGGQYDK---SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICD 479 E+ YGG +G+F PT+ E FGP+++V Y D +E Sbjct: 345 A-ELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYND--LDEAIQ 401 Query: 480 IIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGT 539 I N ++Y L G + KD++ + ++ AG IN+ FGG + SG Sbjct: 402 -IANDTKYGLAGYVIGKDKETLHKVARSIE--AGTVEINEA---GRKPDLPFGGYKQSGL 455 Query: 540 DDKAGGPNILSRFVSIRNTKENFY 563 + G + F+ +++ F Sbjct: 456 GREWGD-YGIEEFLEVKSIAGYFK 478 >6FK3-A nrPDB Length = 536 Score = 429 bits (1103), Expect = e-120, Method: Composition-based stats. Identities = 127/524 (24%), Positives = 209/524 (39%), Gaps = 45/524 (8%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 ++LE ++ GE + E L + NP++ + V+A +A + V A A++A + Sbjct: 15 GNTLEFGHLVGGEEVL---EGPLLERRNPSDREDVVARFPEADKDLVRKAALKAREAFAE 71 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W P R + ++ + + + + GK +A D + E D ++ Sbjct: 72 WSRTPAPIRGQVLFNLVKILE-REKPTLTRLMVREVGKTPKEAAGD-VQEAIDTALFFAS 129 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPA-LMGNTVVWK 234 LY Q RPL G V ++ NF + PA L GNTVVWK Sbjct: 130 EGRRLYGQTVPSEMRDKELFTFRRPL-GVVGIITAGNFPIAVPSWKLIPAVLTGNTVVWK 188 Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQ----VLADKDFGALHFTGSTN 290 PS+ A +++ + EEAGLP GV+N + G T Q ++ + F FTGST Sbjct: 189 PSEDAPTLSFVFAKLFEEAGLPPGVLNVVFGGGKGSTGQWMVELMDEGLFQKFAFTGSTQ 248 Query: 291 VFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQK 350 V + + E R+ R E GGKN +V A++ AV F GQ+ Sbjct: 249 VGRWI--------GEVAGRNLIRPTLELGGKNPLVVMRDADLDLAVEGAWWSAFATGGQR 300 Query: 351 CSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDK 410 C++A + + EEF +++ V +P+ GP I+E+ F + Sbjct: 301 CTSAGNILVDAPIYEEFKRRFLERVEATLV------GNPLLH--PEVTYGPFINERFFAR 352 Query: 411 LVKVIEDAKKDPELEILYGGQY-----------DKSQGWFVGPTVIKAKRPDHPYMSTEF 459 + + + + G+ D G + PTV + RP + E Sbjct: 353 WQEHYRVGEAEGARLLFGRGRITRENPYPRFLGDPEAGLYGWPTVWE-VRPGTRLFTEEV 411 Query: 460 FGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYIND 519 FGP + + + E + N++ Y L+ AI+ R K+ AG IN+ Sbjct: 412 FGPTINLVKVDGI---EEAIAVANSTPYGLSSAIYTNHRHWAYLF--KVGIRAGMTSINN 466 Query: 520 KCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFY 563 GA + FGG + SG + G +L + E + Sbjct: 467 ATVGAE-AHLPFGGVKASGNGGRESGIWVLEEYTYWHAVNEEYS 509 >4U3W-A nrPDB Length = 505 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 132/506 (26%), Positives = 209/506 (41%), Gaps = 41/506 (8%) Query: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD-WYNLPF 121 INGE + FP +P + ++ LA+V +A V +AV+AA A+K W + Sbjct: 26 HYINGEFV---ASGTTFPNLSPVDGRK-LADVCEADAALVDSAVQAAHAAQKAGWRDTTP 81 Query: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY---AS 178 R+A K AD I ++ + +AA + G+ V QA I FR + AS Sbjct: 82 AQRAAWLHKIADGIEARF-DEFVAAEVADTGRPVAQARTLDIARGIANFRTFADLVRTAS 140 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQ 237 Y + N +PL G + +SP+N + APAL MGN VV KPS+ Sbjct: 141 GEYFETHAADGSELINYVTRKPL-GVIGIISPWNLPLLLFTWKVAPALAMGNCVVAKPSE 199 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPV-QVTDQVLADKDFGALHFTGSTNVFKSLY 296 S LL V+ + GLP GV N I G + + D A+ FTG + ++ Sbjct: 200 ETPSSATLLAEVMHDVGLPPGVFNLIHGHGQNAAGEFLTRHPDISAITFTGESRTGSTIM 259 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASR 356 + GV + E GGKN +V A+ AV +R +F GQ C + R Sbjct: 260 KAVADGV--------KEVSFELGGKNAAVVFADADFDAAVAGVLRSSFTNAGQVCLCSER 311 Query: 357 LYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIE 416 +Y+ E F++ + Q+ V A MGP+I DK++ Sbjct: 312 VYVERPIFERFVAALKEQAQALRVGAPEDPA---------TTMGPLISRGHRDKVLSYFR 362 Query: 417 DAKKDPELEILYGGQY----DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 A ++ + GG + G FV PT+ + E FGP+ + + D Sbjct: 363 LAVEEGATVVTGGGAPSFGDARDDGAFVMPTIWTGLPDSARCVREEIFGPVCHIAPFDDE 422 Query: 473 EFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFG 532 E+ + N S Y L +I+ ++++ G ++N + + FG Sbjct: 423 A--EVVKRV-NDSAYGLAASIWTTQLARGHRVAKQIE--TGIVWVNAWFVRDL--RTPFG 475 Query: 533 GARMSGTDDKAGGPNILSRFVSIRNT 558 G ++SG + GG + L + + N Sbjct: 476 GTKLSGLGRE-GGRHSLDFYSELTNV 500 >3U4J-A nrPDB Length = 528 Score = 425 bits (1092), Expect = e-119, Method: Composition-based stats. Identities = 115/516 (22%), Positives = 204/516 (39%), Gaps = 32/516 (6%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK--KDWYN 118 ++++G+ + D + + +P + +V+ +A+ DV AV AA+ A W Sbjct: 23 YQMLVDGKSV-DAASGSTIDRVSPGHAGEVVGTWPEASADDVRKAVAAARKAFDAGPWPR 81 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 + +RS + K ADLI + + ++ L GK + QA + I +D + Y A Sbjct: 82 MSGAERSRLMFKVADLILAR-QEELALIESLEVGKPIAQARGE-IGFCADLWSYAAGQAR 139 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQ 237 L Q D P+ G V ++P+NF I A+ A+ G TVV KPS+ Sbjct: 140 ALEGQTHNNIGDDRLGLVLREPV-GVVGIITPWNFPFIIASERVPWAIGSGCTVVLKPSE 198 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 + ++ L + EAG+P GV N + G + D + + FTGS V L Sbjct: 199 FTSGTSIRLAELAREAGIPDGVFNVVTGYGDPAGQVLAEDPNVDMVAFTGSVRVGTKL-- 256 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 E R R+ E GGK +V A++ A G + GQ C + SRL Sbjct: 257 ------GEIAARTVKRVGLELGGKGPQIVFADADLDAAADGIAYGVYHNAGQCCISGSRL 310 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 + E + + + I + P++ R +G +I E +K+ + Sbjct: 311 LVQEGIRDALMERLLDISRKV------AFGDPLNE---RTKIGAMISEAHAEKVHSYVTA 361 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 +L G + + G + PTV PD E FGP+L+ + + Sbjct: 362 GITSGAELLLGGERIGREAGLYYAPTVFAGVTPDMSIAREEIFGPVLSTLTFKTADE--- 418 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 + N +++ L+ ++++ + + +++ AG +IN G + GG + S Sbjct: 419 AVALANATEFGLSASVWSTNLETALQTIRRIR--AGRCWINSVIDG--TPELPIGGYKKS 474 Query: 538 GTDDKAGGPNILSRFVSIRNTKENFYELTDFKYPSN 573 G + G + + + N Sbjct: 475 GLGRELGR-YGFDEYSQFKGVHVTLGRPAPWFTAEN 509 >1T90-A nrPDB Length = 486 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 124/511 (24%), Positives = 215/511 (42%), Gaps = 32/511 (6%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119 ++ INGE + ++ NPA + VL V +T++D+ A + A +A K W + Sbjct: 5 KLKNYINGEWVESKTDQY-EDVVNPATKE-VLCQVPISTKEDIDYAAQTAAEAFKTWSKV 62 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 R+ I L+S +++ ++ + GKN +A + + + + A Sbjct: 63 AVPRRARILFNFQQLLS-QHKEELAHLITIENGKNTKEA-LGEVGRGIENVEFAAG-APS 119 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQT 238 L + S A YR G V ++PFNF + + A+ GNT + KPS+ Sbjct: 120 LMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPSER 179 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 L L+ + E+AGLPKGV N + G V + +L + A+ F GS V + +Y K Sbjct: 180 TPLLTEKLVELFEKAGLPKGVFNVVYG-AHDVVNGILEHPEIKAISFVGSKPVGEYVYKK 238 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 + R+ TG KN +V AN+ V + + F G++C A + + Sbjct: 239 --------GSENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVT 290 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + E ++EF++ + + + +G + F+GPVI E + + + IE Sbjct: 291 VEEGIADEFMAKLQEKVADIKIG---------NGLDDGVFLGPVIREDNKKRTLSYIEKG 341 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 ++ + G + G+FVGPT+ + E F P+L+V + E Sbjct: 342 LEEGARLVCDGRENVSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKN--LKEAI 399 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + I N S++A +F + AI Y E + AG IN + + F G + S Sbjct: 400 E-IANKSEFANGACLFTSNSNAIRYFRENI--DAGMLGINLGVPAPM-AFFPFSGWKSSF 455 Query: 539 TD-DKAGGPNILSRFVSIRNTKENFYELTDF 568 A G + + + + Y DF Sbjct: 456 FGTLHANGKDSVDFYTRKKVVTAR-YPAPDF 485 >5TJR-A nrPDB Length = 531 Score = 422 bits (1086), Expect = e-118, Method: Composition-based stats. Identities = 119/530 (22%), Positives = 212/530 (40%), Gaps = 41/530 (7%) Query: 55 KSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKK 114 K S + +I GE I D NP+ + V V A + + A+ AAK A Sbjct: 31 KGSMTLIKHLIGGELIADT--GRTADVFNPSTGEAV-RKVPLADRETMQQAIDAAKAAFP 87 Query: 115 DWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYV 174 W N P R+ + + L+ ++ GK + A + + + Y Sbjct: 88 AWRNTPPAKRAQVLFRFKQLLEANE-ERIVKLISEEHGKTIEDAAGE-LKRGIENVEYAT 145 Query: 175 KYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVW 233 L + ++++P+ G V ++PFNF A+ + A+ GNT + Sbjct: 146 AAPEILKGEYSRNVGPNIDAWSDFQPI-GVVAGITPFNFPAMVPLWMYPLAIACGNTFIL 204 Query: 234 KPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFK 293 KPS+ S L+ + EAGLPKGV+N + GD V D ++ + AL F GST + + Sbjct: 205 KPSERDPSSTLLIAELFHEAGLPKGVLNVVHGDKGAV-DALIEAPEVKALSFVGSTPIAE 263 Query: 294 SLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 353 +Y + + R+ G KN ++ P A++ +AV + + + G++C A Sbjct: 264 YIYSE--------GTKRGKRVQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMA 315 Query: 354 ASRLY-LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLV 412 S + + ++ + + ++ + + MGP++ + DK+ Sbjct: 316 ISVAVCVGDQIADALVQKLVPQIKGLKIGAGTSCG---------LDMGPLVTGAARDKVT 366 Query: 413 KVIEDAKKDPELEILYGGQYD---KSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEY 469 I+ ++ G Y G+F+G T+ P+ E FGP+L + Sbjct: 367 GYIDTGVAQGAELVVDGRGYKVAGHENGFFLGGTLFDRVTPEMTIYKEEIFGPVLCIVRV 426 Query: 470 PDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQ 529 E E +I N +Y IF +D +A ++++ G +N V Sbjct: 427 NSLE--EAMQLI-NDHEYGNGTCIFTRDGEAARLFCDEIEV--GMVGVNVPLPVPVAYHS 481 Query: 530 WFGGARMSGTDD-KAGGPNILSRFVSIRNT-----KENFYELTDFKYPSN 573 FGG + S D A GP+ + + + + +E F +PSN Sbjct: 482 -FGGWKRSLFGDLHAYGPDGVRFYTKRKAITQRWPQRKSHEAAQFAFPSN 530 >5EUY-A nrPDB Length = 491 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 102/511 (19%), Positives = 218/511 (42%), Gaps = 36/511 (7%) Query: 57 SSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDW 116 + ++V INGE + + A +T+P + + +A V ++ +D A+ +A +A K W Sbjct: 5 NIMKVANYINGE-FKEPSTGAFQVKTSPVDGSK-IAEVPRSGREDAREAIDSAFEALKAW 62 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 N+P R+ K ++ + + D + + G + + + + Sbjct: 63 ANIPAIRRAEYLYKMLEVFR-QMKEDFMKILTVEGGGTYRKV-WGEVVFTERLIQNAAEL 120 Query: 177 ASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGA-PALMGNTVVWKP 235 A + ++S + ++ +G V ++P+N+ + A +GNTVV+KP Sbjct: 121 ARHYQGRV-LQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKP 179 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 + ++ +L+ ++ +AGLPKGV N + G V ++++ K + FTG ++ + + Sbjct: 180 ASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREI 239 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAAS 355 K + E GG + ++ ++ +A + + QGQ C++A Sbjct: 240 AAK--------AAGTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAK 291 Query: 356 RLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415 R+ + ++ +++F+ ++ + + + +GP+I+E+ + + + Sbjct: 292 RIIVHKAVADKFIERYVHYVKMLRIDDPRK--------DEKVDLGPLINERQVALMKEFV 343 Query: 416 EDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFN 475 +DA ++ G +S G F P + + M E FGP+ + E + Sbjct: 344 DDAVSRGGRLLIGG----RSWGNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVV---END 396 Query: 476 EICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGAR 535 + + N + Y L+GA+ + E ++ +G F+IND T S FGG + Sbjct: 397 DQAVEVANDTDYGLSGAVLTNNVNRAFRIAEAVE--SGMFHIND-VTFLEESHVPFGGIK 453 Query: 536 MSGTDDKAGGPN----ILSRFVSIRNTKENF 562 SG + G + R+V++ F Sbjct: 454 ASGVGREGGEWSFHETTYDRWVTVTLRTRRF 484 >4ZZ7-A nrPDB Length = 501 Score = 419 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 129/528 (24%), Positives = 220/528 (41%), Gaps = 41/528 (7%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 S + +ING+ + +N NPA + + + A+ K V A+ AA+ A Sbjct: 2 SHMTTIGHLINGQLVTENTRSQ--NVFNPATGE-IGKQLDLASTKTVEQAISAAQHAFPT 58 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W N P R+ + + +L+ ++ ++ GK + A + + + Y Sbjct: 59 WRNTPPLKRARVMFRFKELLE-QHADEICRLIGEEHGKIAHDAMGE-LQRGIENVEYACG 116 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWK 234 L + G + +E++P+ G V ++PFNF + + A+ GN V K Sbjct: 117 APELLKGEHSRNVGPGIDSWSEFQPM-GVVAGITPFNFPVMVPLWMFPMAIVCGNCFVLK 175 Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKS 294 PS+ S + +L+EAGLP GV+N + GD + D +L D A+ F GST + + Sbjct: 176 PSERDPSSTLYIAQLLQEAGLPDGVMNVVNGD-KEAVDALLHDDRVKAVSFVGSTPIAEY 234 Query: 295 LYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAA 354 +Y + R G KN +V P A++ +AV + F G++C A Sbjct: 235 IY--------RTASANGKRCQALGGAKNHAIVMPDADMDNAVNQLLGAAFGSSGERCMAL 286 Query: 355 SRLY-LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 S + ++ + +S M +Q V P S + GPVI Q +K++ Sbjct: 287 SVAVAVGDAAGDALVSKMTQAMQKLKVGPSTDSGNDF---------GPVITRQHQEKVIG 337 Query: 414 VIEDAKKDPELEILYGGQ---YDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP 470 I A++ ++ G Q + G+FVG T+I P+ E FGP+L V Sbjct: 338 YINSAEQQGATIVVDGRQPKVPNHENGFFVGGTLIDHVTPEMTSYQEEIFGPVLQVVRVA 397 Query: 471 DTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW 530 + D+ID +Y IF +D +A Y + ++ G IN V Sbjct: 398 T--MQDAMDLID-AHEYGNGTCIFTRDGEAARYFSDNIQV--GMVGINIPLPVPVAYHS- 451 Query: 531 FGGARMSGTDD-KAGGPNILSRFVSIRNTKENF-----YELTDFKYPS 572 FGG + S D A GP+ + + + + + E +F P+ Sbjct: 452 FGGWKRSLFGDLHAYGPDAVRFYTKRKTVTQRWPSAGVREGAEFSMPT 499 >5X5U-A nrPDB Length = 505 Score = 417 bits (1071), Expect = e-117, Method: Composition-based stats. Identities = 115/501 (22%), Positives = 198/501 (39%), Gaps = 32/501 (6%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119 + L+I+GE + D NPA + + V A D+ A+ AA+ + W + Sbjct: 32 DTQLLIDGEWV-DAASGKTIDVVNPATGKP-IGRVAHAGIADLDRALAAAQSGFEAWRKV 89 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 P ++R+A KAA L+ + + QGK + +A ++ + +D ++ Sbjct: 90 PAHERAATMRKAAALVRERA-DAIAQLMTQEQGKPLTEARVE-VLSAADIIEWFADEGRR 147 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQT 238 +Y + G P+ G V A +P+NF + AL G + + K + Sbjct: 148 VYGRIVPPRNLGAQQTVVKEPV-GPVAAFTPWNFPVNQVVRKLSAALATGCSFLVKAPEE 206 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 S L+ +AG+P GVI + GDP +++ ++ + FTGST V K L Sbjct: 207 TPASPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGKQLASL 266 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 R E GG +V A+++ AV + F GQ C + +R Sbjct: 267 AG--------LHMKRATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFL 318 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + S +EF + + V +G + + + + VI++A Sbjct: 319 VHNSIRDEFTRALVKHAEGLKVGNGLEEG---------TTLGALANPRRLTAMASVIDNA 369 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 +K I GG+ S+G F PTVI D + E FGP+ + + E Sbjct: 370 RKVGAS-IETGGERIGSEGNFFAPTVIANVPLDADVFNNEPFGPVAAIRGFDKL---EEA 425 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 N + L G F + + ++L+ G +IN T + FGG + SG Sbjct: 426 IAEANRLPFGLAGYAFTRSFANVHLLTQRLEV--GMLWINQPATP--WPEMPFGGVKDSG 481 Query: 539 TDDKAGGPNILSRFVSIRNTK 559 + GGP L ++ ++ Sbjct: 482 YGSE-GGPEALEPYLVTKSVT 501 >2JG7-A nrPDB Length = 510 Score = 417 bits (1071), Expect = e-117, Method: Composition-based stats. Identities = 122/514 (23%), Positives = 210/514 (40%), Gaps = 36/514 (7%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 S + P V NG + PAN++ +A VTQAT + V+ ++A K Sbjct: 17 GLSEDNPGVYNGSW---GGSGEVITSYCPANNEP-IARVTQATLAEYEETVQKTREAWKM 72 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W ++P R I + D + K + + + L GK +Y + + E D Y V Sbjct: 73 WADIPAPKRGEIVRQIGDALRKKIKV-LGSLVSLEMGK-IYVEGVGEVQEYVDVCDYAVG 130 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWK 234 + + G ++ P+ G V ++ FNF A AL GN +WK Sbjct: 131 LSRMIGGPVLPSERPGHALIEQWNPV-GLVGIITAFNFPVAVYGWNNAIALTCGNVCLWK 189 Query: 235 PSQTAALSNY----LLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTN 290 + T L++ ++ VLE+ LP + + G + + D+ L FTGST+ Sbjct: 190 GAPTTPLTSVAVTKIVAEVLEQNNLPGAICSMTCG-GADIGTAMAKDERVDLLSFTGSTH 248 Query: 291 VFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQK 350 V K + +Q + R + E GG N +V A+++ V S + + GQ+ Sbjct: 249 VGKMVAMMVQ--------ERFGRKLLELGGNNAIIVFEDADLNLVVPSAVFASVGTAGQR 300 Query: 351 CSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDK 410 C+ RL L ES + + + + + + GP+ +Q+ D+ Sbjct: 301 CTTTRRLMLHESVHDAVVERIAKAYKQVRIGDP---------WDPSTLYGPLHTKQAVDQ 351 Query: 411 LVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP 470 + IE AK+ ++ GG+ G +V PT+I D P + TE F PIL V ++ Sbjct: 352 YLAAIEQAKQQGGT-LVCGGKVMDRPGNYVEPTIITGLAHDAPIVHTETFVPILYVLKFK 410 Query: 471 DTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW 530 E +N Q L+ +IF KD + G +N +GA + Sbjct: 411 T---EEEAFAWNNEVQQGLSSSIFTKDLGRVFRWLGPKGSDCGIVNVNIPTSGAEIGGA- 466 Query: 531 FGGARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 FGG + +G ++G + +++ N+ + Sbjct: 467 FGGEKHTGGGRESGS-DSWKQYMRRSTCTINYSK 499 >4LIH-A nrPDB Length = 504 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 124/512 (24%), Positives = 216/512 (42%), Gaps = 38/512 (7%) Query: 53 KFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA 112 K S +E I+G D + F +P + +VLA V E DV AV AA+ A Sbjct: 20 KAASLEIEGRAFIDGAS-RDAHGGRTFDCVSPIDG-RVLAKVADCGEADVNAAVAAARRA 77 Query: 113 KKD--WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFF 170 W L R A+ L+ A L+ ++ ++ L GK + + + Sbjct: 78 FDAGVWAGLNPRARKAVLLRWAALMR-EHLDELSLLETLDAGKPIGDTTTVDVPGAAYCV 136 Query: 171 RYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GN 229 ++ + + + V AD R G V AV P+NF + A PAL GN Sbjct: 137 EWFAEAIDKVGGE--VAPADHHLVGLVTREPVGVVAAVVPWNFPILMAAWKFGPALAAGN 194 Query: 230 TVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGST 289 +VV KPS+ + L+ + + EAG+P GV N +PG + + +D + FTGST Sbjct: 195 SVVLKPSEKSPLTAIRVAQLAFEAGIPAGVFNVVPGAG-EPGKLLALHRDVDCIAFTGST 253 Query: 290 NVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA-NISHAVLSTIRGTFEFQG 348 V K + + R E GGK+ ++V P ++ A + F G Sbjct: 254 AVGKLIMQ-------YAAQSNLKRAWLELGGKSPNIVLPDCPDLDRAAQTAAGAIFYNMG 306 Query: 349 QKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSF 408 + C+A SRL + + F+ + ++ +P+ + MG ++ Sbjct: 307 EMCTAGSRLLVHRDIKDAFIEKLVAAARA------YVPGNPL---DPSVSMGAIVDGIQL 357 Query: 409 DKLVKVIEDAKKDPELEILYGGQY--DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTV 466 ++++ IE + + ++ GG ++ G++V PTV + +PD E FGP+L+V Sbjct: 358 ERVLGYIEAGRGEG--RLVTGGARVNAETGGFYVEPTVFE-VKPDAKIAREEIFGPVLSV 414 Query: 467 YEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVV 526 + D + I N ++Y L A++ + +L+ AG ++N G + Sbjct: 415 IVFDDVDE---AVRIANDTEYGLAAAVWTSNLTTAHDVSRRLR--AGTVWVNCYDEGGDM 469 Query: 527 SQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 FGG + SG + L ++ +++T Sbjct: 470 -NFPFGGYKQSGNGRDK-SLHALEKYTELKST 499 >3RH9-A nrPDB Length = 506 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 123/513 (23%), Positives = 206/513 (40%), Gaps = 35/513 (6%) Query: 58 SLEVPLVIN-----GERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDA 112 +E PL+ N G R D+ A F NPA V+A V E+DV+ AV+A + A Sbjct: 3 MIESPLLENLTGYIGGRWKDSAGGATFDVYNPATGS-VIAKVPSMPEEDVVAAVEAGQSA 61 Query: 113 KKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRY 172 + P R D + + R ++ + GK +A+ + + + FF Y Sbjct: 62 LRLTNPWPIETRRKWLEDIRDGL-KENREEIGRILCMEHGKPWKEAQGE-VDYAAGFFDY 119 Query: 173 YVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTA-IAANLIGAPALMGNTV 231 K+ S L + E YRP+ G + P+NF + A + A G Sbjct: 120 CAKHISALDSHTIPEKPKDCTWTVHYRPV-GVTGLIVPWNFPIGMIAKKLSAALAAGCPS 178 Query: 232 VWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNV 291 V KP+ L+ +V+++ LP G++N + G + + KD L FTGST V Sbjct: 179 VIKPASETPLTMIAFFSVMDKLDLPDGMVNLVMGKASVIGKVLCEHKDVPMLSFTGSTEV 238 Query: 292 FKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKC 351 + L + ++ E GG +V A++ A + I F GQ C Sbjct: 239 GRKL--------IVDTAEQVKKLALELGGNAPFIVFDDADLEAAADNLIANKFRGGGQTC 290 Query: 352 SAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKL 411 A+R+++ E ++ F + + V +GP+I++Q FDK+ Sbjct: 291 VCANRIFVHEKVADAFGQKLAERVNKMTVGDGMNDG---------IDIGPLINKQGFDKV 341 Query: 412 VKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPD 471 + ++DA + + G F PTV++ + E FGP++ + + Sbjct: 342 KRHLQDALDKGASLVAGKQPAELGDGLFFPPTVVQGVDREMCCYQEETFGPLVPMALFRT 401 Query: 472 TEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWF 531 E E+ D N +++ L +F D + + L+F G+ N + F Sbjct: 402 EE--EVID-AGNDTEFGLASYVFTADAERAQRVAAGLRF--GHVGWNTGT--GPTPEAPF 454 Query: 532 GGARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 GG + SG + GG L FV + F E Sbjct: 455 GGMKASGIGRE-GGLEGLFEFVEAQTVPRGFAE 486 >5VBF-A nrPDB Length = 478 Score = 410 bits (1055), Expect = e-115, Method: Composition-based stats. Identities = 116/503 (23%), Positives = 194/503 (38%), Gaps = 32/503 (6%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119 + L I+G R +D + R P +P +VL + AT D+ AV+AA A W + Sbjct: 6 PLRLYIDG-RFHDADGRRTQPVVDPGT-TRVLGELPHATAHDIDAAVQAAHRAFVTWRHE 63 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 RS + L+ A ++ + + + QGK + +A I + ++ ++ + Sbjct: 64 SPLVRSDL-LRRAAALARERAETIGRHITMDQGKPLREA-IAEVVSAAEQLEWHAEEGRR 121 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQT 238 Y + + P+ G A SP+NF A A AL G T+V K + Sbjct: 122 TYGRVVPARSPDVMQTVLREPI-GVCAAFSPWNFPFSQAMHKIAAALASGCTLVLKGPEE 180 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 + + L + +AGLP G +N + G P V+ Q++ + FTGS V K L Sbjct: 181 SPSAIVALAQLFHDAGLPPGCLNIVWGVPGDVSKQLIEAPQVRKISFTGSVPVGKQLAAL 240 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 R+ E GG LV A++ A F GQ C + +R + Sbjct: 241 --------AASLMKRMTMELGGHAPVLVCADADVERAAAMLAAYKFRNAGQVCVSPTRFF 292 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + + + F+ + + V G + MGP+ H + D++ + DA Sbjct: 293 VQRAAFDRFVCAYLDAVGTIRVG---------YGLDAGVTMGPLAHARRVDEIDAFVADA 343 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 +I GG G + PTV+ D M+ E FGPI+ + + D + Sbjct: 344 TAKGA-QIATGGMRLPGPGHYFAPTVVLGPTRDTRLMNDEPFGPIVGIVPFDDLDDALAE 402 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 N + L F + L+ AG IN G ++ FGG + SG Sbjct: 403 ---ANRLPFGLASYAFTTSARNAHRISRALE--AGMVNINHFGMGP--AEIPFGGVKDSG 455 Query: 539 TDDKAGGPNILSRFVSIRNTKEN 561 + GG ++ + + Sbjct: 456 FGSE-GGMEAFDGYLVTKFVTQM 477 >4JZ6-A nrPDB Length = 500 Score = 410 bits (1053), Expect = e-114, Method: Composition-based stats. Identities = 120/502 (23%), Positives = 229/502 (45%), Gaps = 36/502 (7%) Query: 59 LEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYN 118 ++ L IN I D++++ F + +P + +V+ AT D + A +AA++A K W + Sbjct: 18 MKTKLFINNAWI-DSSDQQTFERKHPVS-SEVMTESANATVTDAIKAAQAAEEAFKTWKD 75 Query: 119 LPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYAS 178 + +R + LK AD++ +K + + G + A + + ++ FR A+ Sbjct: 76 VGPSERRRLLLKVADVMESKT-PKFIEVMAMEVGASALWAGFN-VHASANVFREAASLAT 133 Query: 179 DLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGA-PALMGNTVVWKPSQ 237 + + T + +P+ G + ++ P+N TA+ A A P + GNTVV+K S+ Sbjct: 134 QIQGETIPTDKAETLSMTLRQPV-GPILSIVPWNGTAVLAARAIAYPLVCGNTVVFKGSE 192 Query: 238 TAALSNYLLMTVLEEAGLPKGVINFIPGDP---VQVTDQVLADKDFGALHFTGSTNVFKS 294 + ++ L+ ++EAGLP GV+N++ P ++ D +++ K+ ++FTGST V Sbjct: 193 FSPATHALITQCVQEAGLPAGVLNYLNSSPDRSPEIADALISAKEIRRINFTGSTRVGSI 252 Query: 295 LYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAA 354 + K + R + E GGK+ +V A+I+ AV + + G+F FQGQ C + Sbjct: 253 IAQK--------AAQHLKRCLLELGGKSPLIVLDDADINAAVKAAVFGSFLFQGQICMST 304 Query: 355 SRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKV 414 RL + E ++EF++ + +V + +GP++ S +++ + Sbjct: 305 ERLVVDEKIADEFVARFVEKTERLSVGDPCLTGD--------CIIGPMVSPNSGERINGL 356 Query: 415 IEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEF 474 +DA +++ GG QG + T++ + D E FGPI V Sbjct: 357 FKDAIDKGA-KVVCGGMA---QGAVMPATILDHVKSDMRIYDEETFGPITVVIRCKG--- 409 Query: 475 NEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGA 534 I N S Y L+ +F +D +++ G +IN +Q +GG Sbjct: 410 EAEAIRIANDSVYGLSSGVFGRDINRALRVGMSIEY--GCVHINGSTVQNE-AQAPYGGT 466 Query: 535 RMSGTDDKAGGPNILSRFVSIR 556 + +G G ++ F ++ Sbjct: 467 KNTGYGRFDGR-AVIDEFTELK 487 >3R64-A nrPDB Length = 508 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 134/509 (26%), Positives = 227/509 (44%), Gaps = 36/509 (7%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLP 120 +I G+ + N++R + NP + V+A QA+ DV A +AAK A+ +W P Sbjct: 13 TKHLIGGQWVEGNSDR-ISTNINPYD-DSVIAESKQASIADVDAAYEAAKKAQAEWAATP 70 Query: 121 FYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 +RSAI +AA+L+ ++R +++ + G +A ++ IT + + + + Sbjct: 71 AAERSAIIYRAAELLE-EHREEIVEWLIKESGSTRSKANLE-ITLAGNITKESASFPGRV 128 Query: 181 YAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTA 239 + + + G N+ YR +G V +SP+NF + APAL GN VV KP+ Sbjct: 129 HGRISPSNTPGKENRV-YRVAKGVVGVISPWNFPLNLSIRSVAPALAVGNAVVIKPASDT 187 Query: 240 ALSN-YLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 ++ + + EEAG+P GVI+ + G ++ D + + FTGST V + + Sbjct: 188 PVTGGVIPARIFEEAGVPAGVISTVAGAGSEIGDHFVTHAVPKLISFTGSTPVGRRV--- 244 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 G + + E GG +V A+I A + G F QGQ C + +R+ Sbjct: 245 ---GELAINGGPMKTVALELGGNAPFVVLADADIDAAAQAAAVGAFLHQGQICMSINRVI 301 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + + +EFL +++ + P + G L +GPVI++ L + IE A Sbjct: 302 VDAAVHDEFLEKFVEAVKNI------PTGDPSAEGTL---VGPVINDSQLSGLKEKIELA 352 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 KK+ + G +G V P V D E FGP+++V + D Sbjct: 353 KKEGATVQVEG----PIEGRLVHPHVFSDVTSDMEIAREEIFGPLISVLKADDEAHAAE- 407 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + N S + L+ A+++KD A L+ +G +IND FGG++ SG Sbjct: 408 --LANASDFGLSAAVWSKDIDRA--AQFALQIDSGMVHINDLTVNDE-PHVMFGGSKNSG 462 Query: 539 TDDKAGGPNI----LSRFVSIRNTKENFY 563 G I R++ I+ + EN Y Sbjct: 463 LGRFNGDWAIEEFTTDRWIGIKRSAENLY 491 >4X0T-A nrPDB Length = 513 Score = 406 bits (1044), Expect = e-113, Method: Composition-based stats. Identities = 118/504 (23%), Positives = 208/504 (41%), Gaps = 36/504 (7%) Query: 66 NGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRS 125 NG + PAN++ +A V QA+ D VK A++A K W ++P R Sbjct: 30 NGSW---GGRGEVITTYCPANNEP-IARVRQASVADYEETVKKAREAWKIWADIPAPKRG 85 Query: 126 AIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQP 185 I + D + K + + + L GK + + + + E D Y V + + Sbjct: 86 EIVRQIGDALREKIQV-LGSLVSLEMGKILVEG-VGEVQEYVDICDYAVGLSRMIGGPIL 143 Query: 186 VESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPA-LMGNTVVWKPSQTAALSNY 244 G ++ P+ G V ++ FNF A A + GN +WK + T +L + Sbjct: 144 PSERSGHALIEQWNPV-GLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISV 202 Query: 245 ----LLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQ 300 ++ VLE+ LP + + G + + D+ L FTGST V K + +Q Sbjct: 203 AVTKIIAKVLEDNKLPGAICSLTCG-GADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQ 261 Query: 301 SGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLP 360 + R + E GG N + A++S V S + GQ+C+ A RL++ Sbjct: 262 --------ERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIH 313 Query: 361 ESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKK 420 ES +E ++ + V + + GP+ +Q+ + +E+AKK Sbjct: 314 ESIHDEVVNRLKKAYAQIRVG---------NPWDPNVLYGPLHTKQAVSMFLGAVEEAKK 364 Query: 421 DPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDI 480 + ++YGG+ G +V PT++ D TE F PIL V+++ + E Sbjct: 365 EGGT-VVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKN---EEEVFA 420 Query: 481 IDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTD 540 +N + L+ +IF KD I G +N +GA + FGG + +G Sbjct: 421 WNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGA-FGGEKHTGGG 479 Query: 541 DKAGGPNILSRFVSIRNTKENFYE 564 ++G + +++ N+ + Sbjct: 480 RESGS-DAWKQYMRRSTCTINYSK 502 >3K2W-A nrPDB Length = 497 Score = 406 bits (1044), Expect = e-113, Method: Composition-based stats. Identities = 118/506 (23%), Positives = 204/506 (40%), Gaps = 36/506 (7%) Query: 64 VINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYD 123 I G+ + +NE +P+ +V+ + + D NA++ A+ A+K W L Sbjct: 16 FIGGQYVP-SNESDTIDILSPSTG-KVIGEIPAGCKADAENALEVAQAAQKAWAKLTART 73 Query: 124 RSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQ 183 R + A+ I + + QGK + AE++ + + F Y A + Sbjct: 74 RQNMLRTFANKIRENKHI-LAPMLVAEQGKLLSVAEME-VDVTATFIDYGCDNALTIEGD 131 Query: 184 QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALS 242 + S + ++ G V ++ +NF A PAL GNT+V KP+Q L+ Sbjct: 132 -ILPSDNQDEKIYIHKVPRGVVVGITAWNFPLALAGRKIGPALITGNTMVLKPTQETPLA 190 Query: 243 NYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSG 302 L + +EAGLP GV+N I G V + + TGST K +Y Sbjct: 191 TTELGRIAKEAGLPDGVLNVINGTGSVVGQTLCESPITKMITMTGSTVAGKQIY------ 244 Query: 303 VVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPES 362 + ++ E GGK +V A++ A + G F GQ C+ RLY+ S Sbjct: 245 --KTSAEYMTPVMLELGGKAPMVVMDDADLDKAAEDALWGRFANCGQVCTCVERLYVHAS 302 Query: 363 KSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDP 422 +EF++ +++ V + MGP +++ D + ++ +A K Sbjct: 303 VYDEFMAKFLPLVKGLKVGDP---------MDADSQMGPKCNQREIDNIDHIVHEAIKQG 353 Query: 423 ELEILYGGQYDKSQGW----FVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 + GG+ +G+ + PTV+ + D+ + E FGPIL + + E + Sbjct: 354 AT-VATGGKTATVEGFEGGCWYEPTVLVDVKQDNIVVHEETFGPILPIVKVSSME--QAI 410 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 + N S Y L+ + + I A L+ G YIN Q + G + SG Sbjct: 411 EFC-NDSIYGLSAYVHTQSFANINQAISDLEV--GEVYINRGM--GEQHQGFHNGWKQSG 465 Query: 539 TDDKAGGPNILSRFVSIRNTKENFYE 564 + G L +++ + N E Sbjct: 466 FGGEDGK-FGLEQYLEKKTVYINEAE 490 >2W8P-A nrPDB Length = 487 Score = 402 bits (1033), Expect = e-112, Method: Composition-based stats. Identities = 112/512 (21%), Positives = 201/512 (39%), Gaps = 36/512 (7%) Query: 51 LMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAK 110 L ++ L + G + A FP +PA+ L V ++ AV+AA Sbjct: 3 LAGLSAALLRTDSFVGGRWLPAA---ATFPVQDPASGAA-LGMVADCGVREARAAVRAAY 58 Query: 111 DAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFF 170 +A W + +RS++ K +L+ + D+ GK + +A + I + F Sbjct: 59 EAFCRWREVSAKERSSLLRKWYNLMIQN-KDDLARIITAESGKPLKEAHGE-ILYSAFFL 116 Query: 171 RYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GN 229 ++ + A +Y A +P+ G ++P+NF + AL G Sbjct: 117 EWFSEEARRVYGDIIHTPAKDRRALVLKQPI-GVAAVITPWNFPSAMITRKVGAALAAGC 175 Query: 230 TVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGD---PVQVTDQVLADKDFGALHFT 286 TVV KP++ S L + +AG+P GV N IP +V + + D + FT Sbjct: 176 TVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFT 235 Query: 287 GSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEF 346 GST K L + V R+ E GG +V SAN+ AV + F Sbjct: 236 GSTTTGKILLHHAANSV--------KRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRN 287 Query: 347 QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQ 406 GQ +++ + + F+ ++ + G + GP+I+E+ Sbjct: 288 TGQTAVCSNQFLVQRGIHDAFVKAFAEAMK-----KNLRVGNGFEEGTTQ---GPLINEK 339 Query: 407 SFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTV 466 + +K+ K + DA ++ GG+ + F PT++ D E FGP+ V Sbjct: 340 AVEKVEKQVNDAVSKGAT-VVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPV 398 Query: 467 YEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVV 526 ++ E + L G +++D I E+L+ G +N+ +V Sbjct: 399 IKFDTEEEAIAIANAADV---GLAGYFYSQDPAQIWRVAEQLEV--GMVGVNEGLISSV- 452 Query: 527 SQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 + FGG + SG + G + ++ ++ Sbjct: 453 -ECPFGGVKQSGLGRE-GSKYGIDEYLELKYV 482 >4DNG-A nrPDB Length = 485 Score = 400 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 129/495 (26%), Positives = 215/495 (43%), Gaps = 34/495 (6%) Query: 64 VINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYD 123 ING+ + R NP + Q V+ + AT K + +A A+ A+K+W D Sbjct: 10 FINGKWTGGESGR-TEDILNPYD-QSVITTASLATGKQLEDAFDIAQKAQKEWAKSTTED 67 Query: 124 RSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQ 183 R A+ KA + + R D++ G + ++ I+ ++ + Y +L Sbjct: 68 RKAVLQKARGYLH-ENRDDIIMMIARETGGTIIKSTIELEQTIA-ILDEAMTYTGELGGV 125 Query: 184 QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALS 242 + V S YR G + ++SPFNF + APA+ GN+VV KP A+S Sbjct: 126 KEVPSDIEGKTNKIYRLPLGVISSISPFNFPMNLSMRSIAPAIALGNSVVHKPDIQTAIS 185 Query: 243 N-YLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQS 301 ++ E AGLP GV+N + D ++ D +L + + FTGST V + + Sbjct: 186 GGTIIAKAFEHAGLPAGVLNVMLTDVKEIGDGMLTNPIPRLISFTGSTAVGRHI------ 239 Query: 302 GVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPE 361 E R + R+ E GG N V A++ AV + I G F QGQ C +R+ + + Sbjct: 240 --GEIAGRAFKRMALELGGNNPFAVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHQ 297 Query: 362 SKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKD 421 +EF+ ++ P P + +GP+I+E+ +K +++IE AK D Sbjct: 298 DVYDEFVEKFTARVKQL---PYGDQTDP------KTVVGPLINERQIEKALEIIEQAKTD 348 Query: 422 PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII 481 + G + G + P V + TE F PI T+ + + E D+ Sbjct: 349 GIELAVEGKRV----GNVLTPYVFVGADNNSKIAQTELFAPIATIIKAGSDQ--EAIDM- 401 Query: 482 DNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDD 541 N ++Y L+ A+F D + E L+ +G ++ND+ FGG + SG Sbjct: 402 ANDTEYGLSSAVFTSDLEKGEKFA--LQIDSGMTHVNDQSVND-SPNIAFGGNKASGVGR 458 Query: 542 KAGGPNILSRFVSIR 556 G P ++ F + Sbjct: 459 -FGNPWVVEEFTVTK 472 >3RHD-A nrPDB Length = 486 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 124/510 (24%), Positives = 220/510 (43%), Gaps = 51/510 (10%) Query: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFY 122 + I+G+ I R NP + + V+ + + ++ A+ A+ K+ NLP Sbjct: 2 MFIDGKWI----NREDMDVINPYSLE-VIKKIPALSREEAKEAIDTAEKYKEVMKNLPIT 56 Query: 123 DRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYA 182 R I + A I + + ++ + GK + QA ++ + F+ Y + Sbjct: 57 KRYNILMNIAKQI-KEKKEELAKILAIDAGKPIKQARVE-VERSIGTFKLAAFYVKE--H 112 Query: 183 QQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAAL 241 + V +D P+ G V A++PFNF + APA+ GN +V PS A L Sbjct: 113 RDEVIPSDDRLIFTRREPV-GIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPL 171 Query: 242 SNYLLMTVLEEA----GLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYG 297 L ++E A +P GV N + G V D+++ ++ + FTGS+ V + + Sbjct: 172 VCIELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITK 231 Query: 298 KIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRL 357 K + +I E GG N ++V A+++ AV + I+G+F + GQ C + + Sbjct: 232 KAG----------FKKIALELGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMI 281 Query: 358 YLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIED 417 + ES +++F+ + NV + + + +GP+I + + + KV+E Sbjct: 282 LVDESIADKFIEMFVNKAKVLNVG---------NPLDEKTDVGPLISVEHAEWVEKVVEK 332 Query: 418 AKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 A + ++L GG+ DK PT+++ D+ TE F P++ + + E + Sbjct: 333 AIDEGG-KLLLGGKRDK---ALFYPTILE-VDRDNILCKTETFAPVIPIIRTNEEEMID- 386 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 I N+++Y L AIF D E L+F G IND FGG + S Sbjct: 387 ---IANSTEYGLHSAIFTNDINKSLKFAENLEF--GGVVINDSSL-FRQDNMPFGGVKKS 440 Query: 538 GTDDKAGGPNILSRFVSIRNT----KENFY 563 G + G + +I+ EN Y Sbjct: 441 GLGRE-GVKYAMEEMSNIKTIIISKAENLY 469 >4PXN-A nrPDB Length = 525 Score = 397 bits (1019), Expect = e-111, Method: Composition-based stats. Identities = 120/497 (24%), Positives = 200/497 (40%), Gaps = 34/497 (6%) Query: 71 YDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLK 130 T+P + QV+A V +A+ D ++A DA K W +P R I + Sbjct: 45 AWGGSGPTVTSTSP-TNNQVIAEVVEASVHDYEEGMRACFDAAKTWMAIPAPKRGEIVRQ 103 Query: 131 AADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESAD 190 D + K + + L GK + + I + E+ D Y V + L Sbjct: 104 IGDALRAKLHH-LGRLVSLEMGKILPEG-IGEVQEIIDMCDYAVGLSRQLNGSIIPSERP 161 Query: 191 GTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNY----L 245 + PL G V ++ FNF AL GN VVWK + T L + Sbjct: 162 NHMMMEVWNPL-GVVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKI 220 Query: 246 LMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVE 305 + +VLE+ LP + G ++ + D + FTGST + ++ + Sbjct: 221 VASVLEKNNLPGAIFTSFCG-GTEIGQAIALDIRIPLVSFTGSTRAGLMVQQQVSA---- 275 Query: 306 GKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSE 365 + + + E G N +V A+I AV S + GQ+C+ RL L E+ + Sbjct: 276 ----RFGKCLLELSGNNAIIVMDDADIQLAVRSVLFAAVGTAGQRCTTCRRLILHENIYQ 331 Query: 366 EFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELE 425 FL + + + + P+ G L +GP+ S + +K I+ K + Sbjct: 332 TFLDQLVEVYKQVRI------GDPLEKGTL---LGPLHTPASKENFLKGIQTIKSQGG-K 381 Query: 426 ILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTS 485 IL+GG +S+G FV PT+++ P P + E FGP+L V ++ E + I+N+ Sbjct: 382 ILFGGSAIESEGNFVQPTIVE-ITPSAPVVKEELFGPVLYVMKFQT--LKEAIE-INNSV 437 Query: 486 QYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGG 545 L+ +IF K I G +N GA + FGG + +G +AG Sbjct: 438 PQGLSSSIFTKRPDIIFKWLGPHGSDCGIVNVNIPTNGAEIGGA-FGGEKATGGGREAGS 496 Query: 546 PNILSRFVSIRNTKENF 562 + +++ N+ Sbjct: 497 -DSWKQYMRRATCTINY 512 >2QE0-A nrPDB Length = 475 Score = 393 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 122/508 (24%), Positives = 213/508 (41%), Gaps = 44/508 (8%) Query: 57 SSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDW 116 + + +NGE NE ++ PA+ + L +V + ++V +AK A+ W Sbjct: 1 MTKQYKNYVNGEWKLSENEIKIYE---PASGAE-LGSVPAMSTEEVDYVYASAKKAQPAW 56 Query: 117 YNLPFYDRSAIFLKAAD-LISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 L + +R+A K AD L+ K + + + + +G Y++ + + ++ Y + Sbjct: 57 RALSYIERAAYLHKVADILMRDKEKIGAILSKEVAKG---YKSAVSEVVRTAEIINYAAE 113 Query: 176 YASDLYAQQ----PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNT 230 + + E+A R G V A+SPFN+ A APAL GN Sbjct: 114 EGLRMEGEVLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNV 173 Query: 231 VVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTN 290 + +KP ++S LL EAGLP GV N I G ++ D ++ + ++FTGST Sbjct: 174 IAFKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTG 233 Query: 291 VFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQK 350 + + + GK I+ GGK+ +V A++ + I G F + GQ+ Sbjct: 234 IGERI----------GKMAGMRPIMLALGGKDSAIVLEDADLELTAKNIIAGAFGYSGQR 283 Query: 351 CSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDK 410 C+A R+ + ES ++E + + + + + A + P+I +S D Sbjct: 284 CTAVKRVLVMESVADELVEKIREKVLALTIGNPEDDAD----------ITPLIDTKSADY 333 Query: 411 LVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP 470 + +I DA + K +G + P + D E FGP+L + Sbjct: 334 VEGLINDANDKGATALT----EIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVT 389 Query: 471 DTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW 530 E E + I N S+Y L +IF D E+L+ G +IN+K T Sbjct: 390 SVE--EAIE-ISNKSEYGLQASIFTNDFPRAFGIAEQLEV--GTVHINNK-TQRGTDNFP 443 Query: 531 FGGARMSGTDDKAGGPNILSRFVSIRNT 558 F GA+ SG + G + ++++ Sbjct: 444 FLGAKKSGAGIQ-GVKYSIEAMTTVKSV 470 >4YWE-A nrPDB Length = 487 Score = 392 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 113/507 (22%), Positives = 193/507 (38%), Gaps = 37/507 (7%) Query: 58 SLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK-KDW 116 E I GE + P +P++ Q A + + T D+ AV AA+DA W Sbjct: 9 MEEAKHFIAGEWTL-PAQLETIPVVDPSDGQP-FATIARGTAPDIERAVAAARDAFAGPW 66 Query: 117 YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKY 176 +R + ++ + + T ++ A GK + QA D +F +Y Sbjct: 67 GAASAAERGRVLMRLSARV-TDSIEELAAIEARDTGKPLKQARADAAALAR-YFEFYAGA 124 Query: 177 ASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKP 235 A L+ + + G P G + P+N+ AL GN V KP Sbjct: 125 ADKLHGET-LPYQAGYTVLTVREP-HGVTGHIVPWNYPMQIFGRSVGAALAAGNACVVKP 182 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 ++ A LS + + EAGLP G +N + G + + + FTGS K Sbjct: 183 AEDACLSVLRVAELAAEAGLPAGALNIVTGYGHEAGAALARHPGIDHISFTGSPATGKL- 241 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAAS 355 V + ++ + E GGK+ +V A++ A+ + + GQ CSA S Sbjct: 242 -------VTQMAAENHVPVTLELGGKSPQIVFADADLDAALPVLVSAIVQNGGQTCSAGS 294 Query: 356 RLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI 415 R+ + + E + + V P GP+I+ + ++ + Sbjct: 295 RVLIERAVYEPLVERLATAFNGLRVGPSRADLD----------CGPLINAKQQQRVWDFL 344 Query: 416 EDAKKDPELEILYGGQY---DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 472 DA+ D + + GQ G++ P +++ P H E FGP+L + D Sbjct: 345 SDAQHDG-IPMAAHGQVVADAPESGFYQAPALLRDVPPSHRLAQEEVFGPVLAAMRFVD- 402 Query: 473 EFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFG 532 + + N + Y L I+ +D +L+ AG +IN+ G V + FG Sbjct: 403 --EDEAVALANGTPYGLVAGIWTRDGARQMRLARRLR--AGQVFINNYGAGGGV-ELPFG 457 Query: 533 GARMSGTDDKAGGPNILSRFVSIRNTK 559 G SG + G L F +++ Sbjct: 458 GVGHSGHGREKG-FEALYGFTALKTIA 483 >3B4W-A nrPDB Length = 495 Score = 391 bits (1005), Expect = e-109, Method: Composition-based stats. Identities = 109/501 (21%), Positives = 193/501 (38%), Gaps = 36/501 (7%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAK--KDWYNL 119 L I G+ + + PA + V V A DV AV AA+ A W + Sbjct: 10 KLFIGGKW-TKPSTSDVIEVRCPATGEYV-GKVPMAAAADVDAAVAAARAAFDNGPWPST 67 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 P ++R+A+ A +++ + + G+ E Y+ A Sbjct: 68 PPHERAAVIAAAVKMLAER-KDLFTKLLAAETGQPPTIIETMHWMGSMGAMNYFAGAADK 126 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQT 238 + + + P+ G V A+ +N A APAL G T+V KP+ Sbjct: 127 VTW-TETRTGSYGQSIVSREPV-GVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAE 184 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 L+ L V E GLP+GV++ +PG ++ + ++ D FTGS+ V + + + Sbjct: 185 TPLTANALAEVFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGREVGRR 243 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 E GGK+ ++ +++ A+ + GQ C +R+ Sbjct: 244 --------AAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQGCVNQTRIL 295 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 P S+ +E ++ + + + V P + A +GP+I E+ ++ I Sbjct: 296 APRSRYDEIVAAVTNFVTALPVGPPSDPA---------AQIGPLISEKQRTRVEGYIAKG 346 Query: 419 KKDPELEILYGGQYDK-SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEI 477 ++ + GG+ + G+F+ PTV E FGP+L + Y E Sbjct: 347 IEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKMTIAQEEIFGPVLAIIPYDTEED--- 403 Query: 478 CDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 I N S Y L G+++ D ++++ G + IN A FGG + S Sbjct: 404 AIAIANDSVYGLAGSVWTTDVPKGIKISQQIR--TGTYGINWY---AFDPGSPFGGYKNS 458 Query: 538 GTDDKAGGPNILSRFVSIRNT 558 G + G P + F ++ Sbjct: 459 GIGRENG-PEGVEHFTQQKSV 478 >3PRL-A nrPDB Length = 505 Score = 390 bits (1001), Expect = e-108, Method: Composition-based stats. Identities = 121/521 (23%), Positives = 222/521 (42%), Gaps = 42/521 (8%) Query: 51 LMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAK 110 +M ++ ++ NGE + + PA+ L ++ ++++V +A++ AK Sbjct: 2 VMALQTEQFNANILRNGEWVESRTGERISISA-PASGVA-LGSIPALSQEEVNDAIQGAK 59 Query: 111 DAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFF 170 DA+K W P ++R + ADL+ + + + M K ++ I ++ +D Sbjct: 60 DAQKIWKIRPIHERVDLLYAWADLLEER-KEIIGELIMHEVAKP-KKSAIGEVSRTADII 117 Query: 171 RYYVKYASDLYAQQP----VESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL 226 R+ A L + + R G V A+SPFN+ A APAL Sbjct: 118 RHTADEALRLNGETLKGDQFKGGSSKKIALVEREPLGVVLAISPFNYPVNLAAAKIAPAL 177 Query: 227 M-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHF 285 + GNTVV+KP+ +LS ++ L +AG P+G+I + G + D ++ + Sbjct: 178 VTGNTVVFKPATQGSLSGIKMVEALADAGAPEGIIQVVTGRGSVIGDHLVEHPGIDMI-- 235 Query: 286 TGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFE 345 + G +G + ++ E GGK+ +V A++ + G F Sbjct: 236 --------TFTGGTTTGERISEKAKMIPVVLELGGKDPAIVLDDADLKLTASQIVSGAFS 287 Query: 346 FQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHE 405 + GQ+C+A R+++ +S +++ ++++ +++ V A + PVI E Sbjct: 288 YSGQRCTAIKRVFVQDSVADQLVANIKELVEQLTVGSPEDDAD----------ITPVIDE 337 Query: 406 QSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILT 465 +S + +I+DA ++ + +K QG + PT++ P E FGP+L Sbjct: 338 KSAAFIQGLIDDALENGATLL----SGNKRQGNLLSPTLLDDVTPAMRVAWEEPFGPVLP 393 Query: 466 VYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAV 525 + D + N S Y L +IF KD + L+ G +IN K T Sbjct: 394 IIRVKDANE---AISLSNQSDYGLQASIFTKDTDRAINIGKHLEV--GTVHINAK-TERG 447 Query: 526 VSQQWFGGARMSGTDDKAGGPNILS---RFVSIRNTKENFY 563 F G + SG + P++LS V++ N EN Y Sbjct: 448 PDHFPFLGVKKSGLGVQGIKPSLLSMTRERVTVLNLAENLY 488 >6MVR-A nrPDB Length = 767 Score = 385 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 130/510 (25%), Positives = 206/510 (40%), Gaps = 52/510 (10%) Query: 60 EVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNL 119 + I G LF NPA Q LA V+QAT+ DV AVKAA+ A+ W Sbjct: 32 DFGHFIGGAW---TAPGDLFATVNPATGQ-TLAQVSQATQADVDAAVKAARKAQPAWAK- 86 Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 R+ + A L+ R L GK + +A + F ++ YA Sbjct: 87 DGAARARVLYALARLLQKHARL-FAVLETLDNGKPIREARDIDVPLAQRHFYHHAGYAQL 145 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQT 238 + + P R G V P+NF + APAL MGNTVV KP++ Sbjct: 146 MGTEMPD------------RAPLGVCGQVIPWNFPLLMLAWKIAPALAMGNTVVLKPAEW 193 Query: 239 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 298 L+ L + +AG+P GV+N + GD V + ++ + FTGST V + + Sbjct: 194 TPLTALLFADICGQAGVPAGVVNIVTGDGA-VGEMIVT-AQVDKVAFTGSTAVGRRIR-- 249 Query: 299 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 358 E + E GGK ++V A+I AV + + QGQ C A SRL Sbjct: 250 ------EATAGTGKALSLELGGKGPYVVCDDADIDSAVEGLVDAIWFNQGQVCCAGSRLL 303 Query: 359 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 418 + E ++ F + + + S + + +G ++H ++ ++ A Sbjct: 304 VQEGIADVFHAKLRARMDSLRIGDPL---------DKCIDIGAMVHPDQLARVRDMVA-A 353 Query: 419 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 478 D E+ Q G + PT+I P P M E FGP+L + E Sbjct: 354 NTDGEV-----YQTAVPAGCYYPPTLISGLAPASPLMQQEIFGPVLVSTTFRT--PAEAV 406 Query: 479 DIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSG 538 +I +N + Y L ++++++ KL AG +IN T + + FGG R SG Sbjct: 407 EIANN-TAYGLAASVWSENVNLALDLAPKL--VAGIVWING--TNMMDAAAPFGGVRESG 461 Query: 539 TDDKAGGPNILSRFVSIRNTKENFYELTDF 568 + GG L+ + ++ + + Sbjct: 462 FGRE-GGWEGLAGYTRPAIATKSPAAVAAY 490 Score = 94.3 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 42/245 (17%), Positives = 79/245 (32%), Gaps = 12/245 (4%) Query: 40 DLKDWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATE 99 L I G++ + P ++L + + + Sbjct: 482 KSPAAVAAYTGDGAADGLDRTAKLYIGGKQ-TRPDGGYSRAVYGP--KGKLLGHASLSNR 538 Query: 100 KDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAE 159 KD+ NAV+ A +A W + R+ I + +S + + GK+ Sbjct: 539 KDLRNAVE-AMNAASGWSRTTGHLRAQILYFIGENLSARADEFANRIKDM-TGKD----G 592 Query: 160 IDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAAN 219 + D +A Q G + G + + P + Sbjct: 593 KAEVAASIDRLFSAAAWADKYDGQVKGVPLRGV--ALAMKEPVGKIGILCPDAAPLLGLV 650 Query: 220 LIGAPAL-MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK 278 + APA+ MGN V S+ L+ VL+ + +P GV+N + G + + + Sbjct: 651 SLMAPAIAMGNRVTLAASEAFPLAATDFYQVLDTSDVPAGVVNILTGAHADLAEPMARHL 710 Query: 279 DFGAL 283 D A+ Sbjct: 711 DLDAV 715 >3ROS-A nrPDB Length = 484 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 99/494 (20%), Positives = 193/494 (39%), Gaps = 41/494 (8%) Query: 79 FPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTK 138 + NP ++ A+ T K + A+ A K W + R+ I A+ + + Sbjct: 6 YQSVNPYTNEA-FASYDNPTSKQIDEAINLAHALYKKWRHEEPASRAEILHDIANAL-KE 63 Query: 139 YRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEY 198 + ++ L GK + +++ + + YY + ++ +P + N Sbjct: 64 HEDELAKMMTLEMGKLLSESK-EEVELCVSICNYYADHGPEML--KPTKLNSDLGNAYYL 120 Query: 199 RPLEGFVYAVSPFNFTAIAANLIGAP-ALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPK 257 + G + A P+NF + AP ++GN ++ K + S L +++ AG P+ Sbjct: 121 KQSTGVIMACEPWNFPLYQVIRVFAPNFIVGNPILLKHAHNVPGSAALTAKIIKRAGAPE 180 Query: 258 G-VINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIG 316 G +IN P ++AD + TGS + S V E ++ + Sbjct: 181 GSLINLYPSY--DQLADIIADPRIQGVALTGS--------ERGGSAVAEAAGKNLKKSTM 230 Query: 317 ETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQ 376 E GG + +V A+ GQ C+++ R+ + +S+ +E L ++ + Sbjct: 231 ELGGNDAFIVLDDADPQVLRNVLNDARTYNDGQVCTSSKRIIVEKSRYDEVLHELKNVFS 290 Query: 377 SQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQ 436 + + P+ + P+ E++ +KL +++A D ++ Y S+ Sbjct: 291 NLK------AGDPLEADTT---LPPMNSEKAKEKLEAQVKEAI-DAGAKVFYQYPEIDSK 340 Query: 437 GWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAK 496 G F PT++ D+P E FGPI V+ D + + N S Y L ++ Sbjct: 341 GAFFRPTILTDIAKDNPVFDKEVFGPIAEVFVVED---DNAAIQLANDSSYGLGSSVIGS 397 Query: 497 DRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRF---- 552 D + +++ G IN + + FGG + SG + G +++ Sbjct: 398 DIDRAKKVSAQIE--TGMTVINGRW--ITSGELPFGGIKKSGYGRELSGLGLMAFVNEHL 453 Query: 553 ---VSIRNTKENFY 563 V+ N EN Y Sbjct: 454 VIDVTKNNQAENLY 467 >3VZ0-A nrPDB Length = 459 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 103/483 (21%), Positives = 184/483 (38%), Gaps = 34/483 (7%) Query: 78 LFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD-WYNLPFYDRSAIFLKAADLIS 136 ++ NP + V + T + + A+ K W R I +AADL+ Sbjct: 6 VYQTLNPTT-ETVERSFDLHTPAQMKDITDRAEHVWKTDWKLRSIAQRKEIVSRAADLLR 64 Query: 137 TKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKA 196 + R + GK + A ++ I +D +Y A + A P++ G Sbjct: 65 -RDRQHHASLIATEMGKALPDA-LEEIDVTADILSFYANGAEEFLAPTPLKVKTGQAKII 122 Query: 197 EYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEEAGL 255 G +Y + P+NF + P LM GN V+ K + + +AG Sbjct: 123 --NQPLGIIYCIEPWNFPYYQLARVAGPNLMAGNVVIAKHAPNVPQCALAFEKLFHDAGA 180 Query: 256 PKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRII 315 P G I D Q + +++ D+ + TGS + V + Sbjct: 181 PVGAYANIFLDNDQ-SAELIKDERIRGVALTGS--------ERAGQAVAAQAGAALKKDT 231 Query: 316 GETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGIL 375 E GG + +V A++ AV + G F GQ C+AA R+ + E + FL + + Sbjct: 232 MELGGSDAFIVLDDADLDLAVKWAVWGRFANNGQVCTAAKRMIVHEKVYDAFLDGLKTAI 291 Query: 376 QSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKS 435 + + + GP+ ++ + + +A K ++ GG+ Sbjct: 292 TRFRIG---------NPLDRDTTHGPMSSLRAMELALDQTAEAVK-GGATLVAGGKRMDR 341 Query: 436 QGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFA 495 +G+F+ PT++ D+P E FGP+ V++ + + N S Y L GA+F+ Sbjct: 342 KGFFMEPTILTDVSKDNPVFYQEIFGPVAVVHKVAS---EQAAIDLANDSPYGLGGAVFS 398 Query: 496 KDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSI 555 +D E E + G +IN A + FGG + SG + + F++ Sbjct: 399 RDIARAEKVAE--QVETGMVFINTAT--AAAPELPFGGIKNSGFGRELSFL-GIEEFINR 453 Query: 556 RNT 558 + Sbjct: 454 KLV 456 >5U0M-A nrPDB Length = 497 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 124/480 (25%), Positives = 200/480 (41%), Gaps = 34/480 (7%) Query: 64 VINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYD 123 I+G + A F P + V + A+ +DV AV+ A+ A W + Sbjct: 15 YIDGLWL--PGHGAPFESVQPVTGETVW-DGNAASLEDVDAAVREARKAFLAWRRKSLAE 71 Query: 124 RSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQ 183 R A+ +L+ + ++ L GK ++++ + + + VK ++ Sbjct: 72 RQAVIEAFGELLEAN-KEELAHQIGLETGKPLWESRTE-VAAMMGKIPISVKAYNERTGH 129 Query: 184 QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALS 242 + A G G V P+NF N PAL GNTVV+KPS+ Sbjct: 130 TESDVAGGH--AVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPGV 187 Query: 243 NYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSG 302 L + + E+AGLP GVIN + G + L FTGS+ V L+ + Sbjct: 188 AELTVRLWEKAGLPDGVINLVQG-GSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFG-- 244 Query: 303 VVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPES 362 + + E GG N +V +++ AV ++ F GQ+C+ A RL +P+ Sbjct: 245 -----GQPEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKG 299 Query: 363 KS-EEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKD 421 K +EFL+ + + V + P FMG VI ++ ++L+K + Sbjct: 300 KKGDEFLARLVEVAARITVAEFDADPQP--------FMGSVISAEAANQLLKAQAAMLEK 351 Query: 422 PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII 481 +L Q G + P ++ A + EFFGP+LTVY Y F+E ++ Sbjct: 352 GATSLLEMKQLKPDTG-LLSPGIVDATGIE--LEDQEFFGPLLTVYRYKG--FDEALELA 406 Query: 482 DNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDD 541 +N ++Y L+ I + DRK E+++ AG N TGA S FGG SG Sbjct: 407 NN-TRYGLSAGILSDDRKLYNRLVEEVR--AGIVNWNRPLTGA-SSAAPFGGVGASGNHR 462 >3EFV-A nrPDB Length = 462 Score = 370 bits (949), Expect = e-102, Method: Composition-based stats. Identities = 103/482 (21%), Positives = 190/482 (39%), Gaps = 33/482 (6%) Query: 81 QTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYR 140 NPA Q LA + A +++ +A+ A K W R+ + + Sbjct: 11 SVNPATGQ-TLAAMPWANAQEIEHALSLAASGFKKWKMTSVAQRAQTLRDIGQALRA-HA 68 Query: 141 YDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRP 200 +M GK + QA + +T+ + +Y ++ + +P + EYRP Sbjct: 69 EEMAQCITREMGKPIKQARAE-VTKSAALCDWYAEHGPAMLNPEPTLV-ENQQAVIEYRP 126 Query: 201 LEGFVYAVSPFNFTAIAANLIGAP-ALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGV 259 L G + A+ P+NF P L GN+ + K + ++ +L EAG P GV Sbjct: 127 L-GVILAIMPWNFPLWQVLRGAVPILLAGNSYLLKHAPNVTGCAQMIARILAEAGTPAGV 185 Query: 260 INFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETG 319 ++ + V+ Q++ D A+ TGS + + + + + E G Sbjct: 186 YGWVNANNEGVS-QMINDPRIAAVTVTGSV--------RAGAAIGAQAGAALKKCVLELG 236 Query: 320 GKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQN 379 G + +V A++ AV + + G ++ GQ C+AA R + E ++ F + Sbjct: 237 GSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFIVEEGIAQAFTDRFVAAAAALK 296 Query: 380 VVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWF 439 + P+ N +GP+ D+L + ++ + + +L GG+ +G + Sbjct: 297 M------GDPLVEEN---DLGPMARFDLRDELHQQVQASVAEGA-RLLLGGEKIAGEGNY 346 Query: 440 VGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRK 499 TV+ PD E FGP+ + D + N S++ L+ IF D Sbjct: 347 YAATVLADVTPDMTAFRQELFGPVAAITVAKDAAH---ALALANDSEFGLSATIFTADDT 403 Query: 500 AIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTK 559 +L+ G +IN A ++ FGG + SG + L F +++ Sbjct: 404 LAAEMAARLE--CGGVFINGY--SASDARVAFGGVKKSGFGRELSH-FGLHEFCNVQTVW 458 Query: 560 EN 561 +N Sbjct: 459 KN 460 >5KF0-A nrPDB Length = 485 Score = 367 bits (941), Expect = e-101, Method: Composition-based stats. Identities = 111/503 (22%), Positives = 188/503 (37%), Gaps = 45/503 (8%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLP 120 P + E +Y N + + + + +V V A + + A+ AA DA K LP Sbjct: 14 YPYYLANEAVYANTDLEVTDKFS----GKVATRVALADAQAIDAAIGAAVDAVKPMRELP 69 Query: 121 FYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 Y R A+ ++ ++ A + GK + + + +T L D FR + A + Sbjct: 70 AYRRQAVLDHCVARFRERF-DELAEALCIEAGKPINDSRGE-VTRLIDTFRVASEEAVRI 127 Query: 181 YAQ----QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKP 235 + + A G P+ G +SPFNF A APAL G V KP Sbjct: 128 DGEVLNLEISARAQGYTGYTRRVPI-GPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKP 186 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 + + ++ VL E LPKG + +P D D+ F L FTGS V +L Sbjct: 187 ASRTPVGALIIAEVLAETNLPKGAFSVLPAHR-DGADLFTTDERFRLLSFTGSPAVGWAL 245 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA--NISHAVLSTIRGTFEFQGQKCSA 353 K +++ E GG +V + + V G + GQ C Sbjct: 246 KEKAGK----------KKVVLELGGNAAAIVDADQFEQLDYVVDRLAFGAYYQSGQSCIG 295 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 R+ + S + + +S + + F+GP+I E +L Sbjct: 296 VQRILVHASLYDTLRDKLVAKTRSLKMGDPK---------DPSTFVGPMISESESRRLSG 346 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 ++ A +I+ GG+ D G T+++ + E FGP+ + ++ Sbjct: 347 WMDAAVAAGA-KIIAGGKVD---GAMFEATLLEDVGREQDLYRKEAFGPVAILEKFD--R 400 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 F++ + N S + L +F + A ++L+ G IND V +GG Sbjct: 401 FDDALARV-NDSDFGLQAGVFTDSLTHAQRAWDELEV--GGVVIND-VPSFRVDNMPYGG 456 Query: 534 ARMSGTDDKAGGPNILSRFVSIR 556 + SG + G + R Sbjct: 457 VKDSGLGRE-GIRYAIEDMTEPR 478 >4E4G-A nrPDB Length = 521 Score = 366 bits (940), Expect = e-101, Method: Composition-based stats. Identities = 117/536 (21%), Positives = 216/536 (40%), Gaps = 39/536 (7%) Query: 47 LRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAV 106 L + F+S E+ I+G+R+ + R NPA + V V A++ D+ AV Sbjct: 13 LGTENLYFQSMMYELGHFIDGKRVAGTSGRVSN-IFNPATGE-VQGTVALASDADLAAAV 70 Query: 107 KAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITEL 166 ++AK A+ W R+ +F+K L++ ++ GK + A+ D + L Sbjct: 71 ESAKAAQPKWAATNPQRRARVFMKFVQLLNDNMN-ELAEMLSREHGKTIDDAKGDIVRGL 129 Query: 167 SDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL 226 + + + L + E A + R G ++PFNF + + APA+ Sbjct: 130 -EVCEFVIG-IPHLQKSEFTEGAGPGIDMYSIRQPVGIGAGITPFNFPGMIPMWMFAPAI 187 Query: 227 -MGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHF 285 GN + KPS+ L ++ EAGLP G++N + GD V D +L D A+ F Sbjct: 188 ACGNAFILKPSERDPSVPIRLAELMIEAGLPAGILNVVNGDKGAV-DAILTHPDIAAVSF 246 Query: 286 TGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFE 345 GST + + +YG + R G KN ++ P A++ A + I + Sbjct: 247 VGSTPIARYVYG--------TAAMNGKRAQCFGGAKNHMIIMPDADLDQAANALIGAGYG 298 Query: 346 FQGQKCSAASRLY-LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIH 404 G++C A S + E + + + +++S + P + + MGPV+ Sbjct: 299 SAGERCMAISVAVPVGEETANRLIDKLVPMVESLRIGPYT---------DEKADMGPVVT 349 Query: 405 EQSFDKLVKVIEDAKKDPELEILYGGQYDK---SQGWFVGPTVIKAKRPDHPYMSTEFFG 461 +++ ++ +I+ + ++ G + G F+G + PD TE FG Sbjct: 350 KEAEQRIRSLIDSGIEQGAKLVVDGRDFKLQGYENGHFIGGCLFDDVTPDMDIYKTEIFG 409 Query: 462 PILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKC 521 P+L+V + + E + +Y AI+ +D A + + G +N Sbjct: 410 PVLSVVRARN--YEEALSLPM-KHEYGNGVAIYTRDGDAARDFAS--RINIGMVGVNVPI 464 Query: 522 TGAVVSQQWFGGARMSGTDD-KAGGPNILSRFVSIRNTKEN----FYELTDFKYPS 572 + FGG + S D G + + + + + +F P+ Sbjct: 465 PVPLAYHS-FGGWKSSSFGDLNQHGTDSIKFWTRTKTITSRWPSGIKDGAEFSIPT 519 >3VZ3-A nrPDB Length = 457 Score = 365 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 109/486 (22%), Positives = 179/486 (36%), Gaps = 33/486 (6%) Query: 74 NERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAAD 133 NP + + T ++ + A++A + + F R AA Sbjct: 1 GSHMAIATINPTTGE-ICQRFKALTPAEIDAKLAKAQEAFQAYRRTSFSQRRQWLENAAA 59 Query: 134 LISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTW 193 ++ + GK +Q+ I + + RYY ++ A + E+ T Sbjct: 60 ILE-RDTSKFAEIMTTEMGKT-HQSAIAEAEKSALVCRYYAEHGEQFLANEYTET-QATE 116 Query: 194 NKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLMTVLEE 252 + Y+PL G + AV P+NF APALM GN V K + + +LE Sbjct: 117 SYVCYQPL-GILLAVMPWNFPFWQVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEA 175 Query: 253 AGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYP 312 AG P+GV + QV +QV+ D A TGS SL + Sbjct: 176 AGFPEGVFQTLLIGASQV-EQVIKDPRVKAATLTGSEPAGASLASLAGQEI--------K 226 Query: 313 RIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMF 372 + E GG + +V PSA++ AV GQ AA R L E+ + EFL + Sbjct: 227 PTLLELGGSDPFVVFPSADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLH 286 Query: 373 GILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQY 432 S + +GP+ E + + ++ A +IL GG+ Sbjct: 287 LKFASLKIGDPMAP---------ETDIGPLATEGILQDISRQVDQAVAAGA-KILLGGRP 336 Query: 433 DKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGA 492 G+F PT++ P + E F P+ V+ D + + N + L + Sbjct: 337 LDRAGYFYPPTILTEIPPGAKILQEELFAPVAMVFTVKDLDQ---AIALANDIPFGLGAS 393 Query: 493 IFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRF 552 + D + ++L AG +IN + FGG + SG + G + F Sbjct: 394 AWTNDPAEQQRFIQEL--DAGAVFINGMVKS--DPRLPFGGTKRSGYGRELG-LAGIRTF 448 Query: 553 VSIRNT 558 V+ + Sbjct: 449 VNAKTV 454 >4OGD-A nrPDB Length = 465 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 103/478 (21%), Positives = 190/478 (39%), Gaps = 37/478 (7%) Query: 76 RALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLP-FYDRSAIFLKAADL 134 + ++P TN +VL T++ + + ++ A K W +R A + A++ Sbjct: 4 QTIYPYTN-----EVLHTFDNMTDQGLADVLERAHLLYKKWRKEDHLEERKAQLHQVANI 58 Query: 135 ISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWN 194 + + R GK +A+ + + +D YY A + P+E+ G Sbjct: 59 LR-RDRDKYAEIMTKDMGKLFTEAQGE-VDLCADIADYYADKADEFLMSTPLETDSG--Q 114 Query: 195 KAEYRPLEGFVYAVSPFNFTAIAANLIGAP-ALMGNTVVWKPSQTAALSNYLLMTVLEEA 253 + G + AV P+NF + AP ++GN +V K + S ++ EA Sbjct: 115 AYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVLEA 174 Query: 254 GLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPR 313 G G I + QV+ QV+ADK + TGS + + + E ++ + Sbjct: 175 GAEAGSITNLFISYDQVS-QVIADKRVVGVCLTGS--------ERGGASIAEEAGKNLKK 225 Query: 314 IIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFG 373 E GG + ++ A+ GQ C+++ R + + + F + Sbjct: 226 TTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKELLTK 285 Query: 374 ILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYD 433 + ++ + + P+ Q+ ++ I+ A D E++YGG+ Sbjct: 286 VFKTAKWGDP---------MDPETTLAPLSSAQAKADVLDQIKLAL-DHGAELVYGGEAI 335 Query: 434 KSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAI 493 G FV PT+I D+P E FGP+ +Y+ E E + + N S Y L G I Sbjct: 336 DHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEE--EAIE-VANDSNYGLGGTI 392 Query: 494 FAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSR 551 F+ +++ + K++ G +IN T + + FGG + SG + S Sbjct: 393 FSSNQEHAKAVAAKIE--TGMSFINSGWTS--LPELPFGGIKHSGYGRELSELGFTSF 446 >5JRY-A nrPDB Length = 485 Score = 360 bits (923), Expect = 1e-99, Method: Composition-based stats. Identities = 114/503 (22%), Positives = 185/503 (36%), Gaps = 45/503 (8%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLP 120 P + +Y N + + + + +V V A K + A+ AA DA K LP Sbjct: 14 YPYYLANAAVYANTDLEVTDKYS----GKVATRVALADAKAIDAAIGAAVDATKPMRELP 69 Query: 121 FYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 Y R A+ ++ ++ A + GK + A+ + +T L D FR + A + Sbjct: 70 AYKRQAVLDHCVARFRERF-DELAEALCIEAGKPINDAKGE-VTRLIDTFRVASEEAVRI 127 Query: 181 YAQ----QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKP 235 + + A G P+ G +SPFNF A APAL G V KP Sbjct: 128 DGEVLNLEISARAQGYTGYTRRVPI-GPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKP 186 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 + + ++ VL E LPKG + +P D D F L FTGS V +L Sbjct: 187 ASRTPVGALIIGEVLAETDLPKGAFSVLPAHR-DGADLFTTDDRFRLLSFTGSPAVGWAL 245 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA--NISHAVLSTIRGTFEFQGQKCSA 353 K +++ E GG +V + + V G F GQ C Sbjct: 246 KEKAGK----------KKVVLELGGNAAAIVDADQLDRLDYVVDRLAFGAFYQSGQSCIG 295 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 R+ + + +S + + F+GP+I E +L Sbjct: 296 VQRILAHADIYDALRDKLIAKTRSLKMGDPK---------DPSTFVGPMISESESRRLSG 346 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 ++ A +I+ GG+ D G T+++ D E FGPI + ++ Sbjct: 347 WMDAAVAAGA-KIVAGGKVD---GAMFEATLLENVGRDQDLYRKEAFGPIAILEKFD--R 400 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 F++ + N S + L +F + A ++L+ G IND V +GG Sbjct: 401 FDDALARV-NDSDFGLQAGVFTDSLAHTQQAWDELEV--GGVVIND-VPSFRVDNMPYGG 456 Query: 534 ARMSGTDDKAGGPNILSRFVSIR 556 + SG + G + R Sbjct: 457 VKDSGLGRE-GIRYAIEDMTEPR 478 >3JU8-A nrPDB Length = 490 Score = 359 bits (921), Expect = 2e-99, Method: Composition-based stats. Identities = 115/488 (23%), Positives = 190/488 (38%), Gaps = 33/488 (6%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 S+++ I G+ + E +P Q V+ + A V AV AA++A Sbjct: 1 SNAMMSTHYIAGQWLAGQGE--TLESLDPV-GQGVVWSGRGADATQVDAAVCAAREAFPA 57 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 W P R + + A + ++ ++ GK ++++ + +T + + V+ Sbjct: 58 WARRPLEQRIELLERFAATLKSRA-DELARVIGEETGKPLWESATE-VTSMVNKVAISVQ 115 Query: 176 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWK 234 + ++ AD T G V P+NF N PAL GN VV+K Sbjct: 116 AFRERTGEKSGPLADAT--AVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFK 173 Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKS 294 PS+ L + +AGLP GV+N + G + + A + L FTGS+ Sbjct: 174 PSELTPKVAELTLKAWIQAGLPAGVLNLVQG-GRETGVALAAHRGLDGLFFTGSSRTGNL 232 Query: 295 LYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAA 354 L+ + + + E GG N +V A++ AV + I+ F GQ+C+ A Sbjct: 233 LHSQFG-------GQPQKILALEMGGNNPLVVEEVADLDAAVYTIIQSAFISAGQRCTCA 285 Query: 355 SRLYLPESKS-EEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 RL +P+ + L+ + + + V + +P FMG VI + + L+K Sbjct: 286 RRLLVPQGAWGDALLARLVAVSATLRVGRFDEQPAP--------FMGAVISLSAAEHLLK 337 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 E +L Q + P ++ EFFGP+L V Y D Sbjct: 338 AQEHLIGKGAQPLLAMTQPIDGA-ALLTPGIL-DVSAVAERPDEEFFGPLLQVIRYSDF- 394 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 N +QY L + + R+ E ++ AG N + TGA S FGG Sbjct: 395 --AAAIREANATQYGLAAGLLSDSRERFEQFL--VESRAGIVNWNKQLTGAASS-APFGG 449 Query: 534 ARMSGTDD 541 SG Sbjct: 450 IGASGNHR 457 >4KNA-A nrPDB Length = 495 Score = 357 bits (916), Expect = 8e-99, Method: Composition-based stats. Identities = 113/481 (23%), Positives = 184/481 (38%), Gaps = 33/481 (6%) Query: 63 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFY 122 L I+G + +F NP +++V A+ DV AV +A+ A W L Sbjct: 12 LFIDGAWVDGA--GPVFASRNPGTNERVW-EGASASADDVERAVASARRAFAAWSALDLD 68 Query: 123 DRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYA 182 R I + A L+ + + + GK +++A + + ++ + + Sbjct: 69 ARCTIVKRFAALLVER-KEALATMIGRETGKPLWEARTE-VASMAAKVDISITAYHERTG 126 Query: 183 QQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAAL 241 ++ ADG G V P+NF N PAL GNTVV+KPS+ A Sbjct: 127 EKRAPMADGV--AVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPG 184 Query: 242 SNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQS 301 + + +AGLP GV+N + G+ + + L FTGS++ L+ + Sbjct: 185 VARATVEIWRDAGLPAGVLNLVQGE-KDTGVALANHRQIDGLFFTGSSDTGTLLHKQFG- 242 Query: 302 GVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPE 361 R + E GG N +V +I AV I+ F GQ+C+ A R+ +P Sbjct: 243 ------GRPEIVLALEMGGNNPLVVAEVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPR 296 Query: 362 SKS-EEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKK 420 + F++ + + + P FMG VI ++ +LV Sbjct: 297 GAFGDRFVARLADVASKITASVFDADPQP--------FMGAVISARAASRLVAAQARLVG 348 Query: 421 DPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDI 480 I+ Q D + G FV ++ E FGP+ + Y D + Sbjct: 349 LGASPIIEMKQRDPALG-FVNAAIL-DVTNVRELPDEEHFGPLAQIVRYTDLDD---AIA 403 Query: 481 IDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTD 540 N + + L+ + A D +A ++ AG N GA S FGGA SG Sbjct: 404 RANDTAFGLSAGLLADDEQAWHTFRRAIR--AGIVNWNRPTNGA-SSAAPFGGAGRSGNH 460 Query: 541 D 541 Sbjct: 461 R 461 >6DBB-A nrPDB Length = 511 Score = 356 bits (914), Expect = 1e-98, Method: Composition-based stats. Identities = 112/502 (22%), Positives = 197/502 (39%), Gaps = 42/502 (8%) Query: 75 ERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADL 134 + +P + LA + T D + AA DA W +P R + ++ Sbjct: 26 KGNALTARSPLDGA-TLATLAVDTPADAERKIDAAHDAFLKWRTVPAPVRGELVRVFGNV 84 Query: 135 ISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWN 194 + +++ ++ L GK + + + E+ D + V + LY G Sbjct: 85 LR-EHKAELGRLVTLEAGK-ITSEGLGEVQEMIDICDFAVGLSRQLYGLTIASERPGHRM 142 Query: 195 KAEYRPLEGFVYAVSPFNFTAIAANLIGAPA-LMGNTVVWKPSQTAALSNYLLMTVLEEA 253 + P+ G +S FNF A A + G++VVWKPS+ L+ +L++A Sbjct: 143 METWHPI-GVCGVISAFNFPVAVWAWNAALAFVCGDSVVWKPSEKTPLTAIACHVLLQKA 201 Query: 254 ---------GL-PKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGV 303 G+ P + + G V + + A K + TGS + + V Sbjct: 202 LREFEKTHPGVAPAELGQLVLGMR-DVGEVLTASKKVPVVSATGSVRMGQE--------V 252 Query: 304 VEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESK 363 + + R I E GG N +V PSA++ V + GQ+C+ RL + S Sbjct: 253 AKVLSQRLARGILELGGNNGMIVAPSADLDLVVRAVTFAAVGTAGQRCTTLRRLIVHRSL 312 Query: 364 SEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPE 423 E+ L + S V +P+ G L +GP++ SFD + K + DA++ Sbjct: 313 VEQLLPRIEKAYASVKV------GNPLEEGTL---VGPLVDRASFDAMQKALADAREQGG 363 Query: 424 LEILYGGQYD--KSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDII 481 E+ G + D + ++V P ++ + E F PIL V Y + F++ D + Sbjct: 364 -EVKGGERVDVGHADAYYVRPAIV-RMPKQSAVVERETFAPILYVMVYDN--FDDAID-V 418 Query: 482 DNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDD 541 N L+ AIF D + E G +N +GA + FGG + +G Sbjct: 419 HNAVPQGLSSAIFTNDMREAEQFMSAAGSDCGIVNVNIGTSGAEIGGA-FGGEKETGGGR 477 Query: 542 KAGGPNILSRFVSIRNTKENFY 563 ++G + ++ N+ Sbjct: 478 ESGS-DAWKAYMRRATNTINYS 498 >5N5S-A nrPDB Length = 515 Score = 356 bits (913), Expect = 2e-98, Method: Composition-based stats. Identities = 118/491 (24%), Positives = 199/491 (40%), Gaps = 42/491 (8%) Query: 73 NNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAA 132 + +R TN + V A V QAT KD+ +A+ AA A + Y+R A+ K Sbjct: 50 DGDRKWLDVTNKYTND-VAAKVPQATHKDIDDAIDAAVAAAPAMAAMGAYERKAVLEKVV 108 Query: 133 DLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPV----ES 188 + ++ ++ + GK + A + +T D F+ + + +Y + Sbjct: 109 AELKNRF-EEIAQTLTMESGKPIKDARGE-VTRTIDTFQVAAEESVRIYGEHIPLDISAR 166 Query: 189 ADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQTAALSNYLLM 247 G + P+ G V VSP+NF APA+ G V KP+ LS +L Sbjct: 167 NKGLQGIVKKFPI-GPVSMVSPWNFPLNLVAHKVAPAIAVGCPFVLKPASRTPLSALILG 225 Query: 248 TVLEEA-GLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEG 306 +L + LP G + +P + D D+ F L FTGS + + + Sbjct: 226 EILHKIEELPLGAFSILPVSR-EDADMFTVDERFKLLTFTGSGPIGWDMKARAGK----- 279 Query: 307 KYRDYPRIIGETGGKNFHLVHPSA-NISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSE 365 +++ E GG +V ++ + + I G F GQ C RLY+ E + Sbjct: 280 -----KKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYVHERLYD 334 Query: 366 EFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELE 425 E ++ + +P ++GP+I E + + +++A + Sbjct: 335 EVKEGFVAAVKKLKM------GNPFEEDT---YLGPMISESAAKGIEDWVKEAVAKGG-K 384 Query: 426 ILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTS 485 +L GG +G F+ PTVI+ + E FGP++ +Y+Y D F E +N + Sbjct: 385 LLTGGN---RKGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSD--FKEAVKECNN-T 438 Query: 486 QYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGG 545 Y L IF KD YA E ++ G +ND V SQ +GG + SG + G Sbjct: 439 HYGLQSGIFTKDLNKAFYAFEHMEV--GGVILNDSPALRVDSQ-PYGGLKDSGIQRE-GV 494 Query: 546 PNILSRFVSIR 556 + + + Sbjct: 495 KYAMDDMLETK 505 >5J6B-A nrPDB Length = 485 Score = 353 bits (906), Expect = 1e-97, Method: Composition-based stats. Identities = 111/490 (22%), Positives = 180/490 (36%), Gaps = 44/490 (8%) Query: 61 VPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLP 120 P + E +Y N E + + +V V A + A+ AA A+K LP Sbjct: 14 YPYYLANEAVYANAELEVTDKY----TGKVATRVALADASAIDAAIAAAVGAQKPLRALP 69 Query: 121 FYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 + R AI ++ ++ A + GK + ++ + +T L D FR + + + Sbjct: 70 AFRRQAILEHCVARFRERF-DELAQALCIEAGKPINDSKGE-VTRLIDTFRVAAEESVRI 127 Query: 181 YAQ----QPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKP 235 + A G + P+ G +SPFNF A APAL G V KP Sbjct: 128 EGGLVNLEISPRAQGYSGYYKRVPI-GPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKP 186 Query: 236 SQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSL 295 + + ++ VL E LPKG + +P D D+ F L FTGS V L Sbjct: 187 ASRTPIGALIIGEVLAETDLPKGAFSILPAHR-DGADLFTTDERFKLLSFTGSPTVGWEL 245 Query: 296 YGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSAN--ISHAVLSTIRGTFEFQGQKCSA 353 K ++ E GG +V + + V G + GQ C Sbjct: 246 KKKAGKKK----------VVLELGGNAAAIVDADQREVLDYVVERLAFGAYYQSGQSCIG 295 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 R+ + + +S + A F+GP+I E +L Sbjct: 296 VQRIIAHADVYDALREKLIAKTRSLKMGDPKDPA---------TFVGPMISESEARRLAG 346 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 +E A +I+ GG+ D G T+++ D E FGP+ + + D Sbjct: 347 WMEAAVAAGA-KIVAGGKVD---GAMFEATLLEGVGRDQDLYRKEAFGPVALLERFSD-- 400 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 F++ + N S + L +F + A ++L+ G IND V +GG Sbjct: 401 FDDALARV-NDSDFGLQAGVFTDSLSHAQRAWDELEV--GGVVIND-VPSFRVDNMPYGG 456 Query: 534 ARMSGTDDKA 543 + SG + Sbjct: 457 VKDSGLGREG 466 >3SZA-A nrPDB Length = 469 Score = 350 bits (897), Expect = 1e-96, Method: Composition-based stats. Identities = 98/458 (21%), Positives = 168/458 (36%), Gaps = 38/458 (8%) Query: 92 ANVTQATE-KDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLG 150 V + + + AVK A+ A P R LI + + +++ A Sbjct: 9 GLVPRGSHMSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQ-ELVGALAAD 67 Query: 151 QGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEY--RPLEGFVYAV 208 KN + A + + + + Y ++ + A +PVE T Y G V + Sbjct: 68 LHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVI 127 Query: 209 SPFNFTAIAANL-IGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDP 267 +N+ + GN VV KPS+ + LL T++ + L K + I G Sbjct: 128 GTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGV 186 Query: 268 VQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVH 327 + T+ + + F + +TGST V K + + + + E GGK+ V Sbjct: 187 PETTELL--KERFDHILYTGSTGVGKII--------MTAAAKHLTPVTLELGGKSPCYVD 236 Query: 328 PSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSA 387 + ++ A G F GQ C A + S + + + L+ S Sbjct: 237 KNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSR 296 Query: 388 SPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKA 447 G +I + F +++ +IE ++ YGG D + ++ PT++ Sbjct: 297 D----------YGRIISARHFQRVMGLIE------GQKVAYGGTGDAAT-RYIAPTILTD 339 Query: 448 KRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEK 507 P P M E FGP+L + E E I N + L +F+ + K I+ Sbjct: 340 VDPQSPVMQEEIFGPVLPIVCVRSLE--EAIQFI-NQREKPLALYMFSSNDKVIKKMIA- 395 Query: 508 LKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGG 545 + S+G ND + FGG SG G Sbjct: 396 -ETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGK 432 >1AD3-A nrPDB Length = 452 Score = 330 bits (845), Expect = 1e-90, Method: Composition-based stats. Identities = 89/447 (19%), Positives = 164/447 (36%), Gaps = 37/447 (8%) Query: 102 VMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEID 161 + + VK A++A R +I+ + + A GKN + + + Sbjct: 3 ISDTVKRAREAFNSGKTRSLQFRIQQLEALQRMINENLK-SISGALASDLGKNEWTSYYE 61 Query: 162 CITELSDFFRYYVKYASDLYAQQPVESADGTWN--KAEYRPLEGFVYAVSPFNFTAIAAN 219 + + + +K D +PV T + G V + +N+ Sbjct: 62 EVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTI 121 Query: 220 L-IGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADK 278 + GN V+ KPS+ + LL T++ + + + + + G + T+ + + Sbjct: 122 QPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELL--KE 178 Query: 279 DFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLS 338 F + +TGST V K V+ + + E GGK+ V ++ A Sbjct: 179 RFDHIMYTGSTAVGK--------IVMAAAAKHLTPVTLELGGKSPCYVDKDCDLDVACRR 230 Query: 339 TIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGF 398 G F GQ C A + S + + + L+ S Sbjct: 231 IAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRD---------- 280 Query: 399 MGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTE 458 G +I+++ F ++ +I++ K + +GG +D+S ++ PT++ P P M E Sbjct: 281 YGRIINDRHFQRVKGLIDNQK------VAHGGTWDQSS-RYIAPTILVDVDPQSPVMQEE 333 Query: 459 FFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYIN 518 FGP++ + E E I N + L +F+ + K I+ + S+G N Sbjct: 334 IFGPVMPIVCVRSLE--EAIQFI-NQREKPLALYVFSNNEKVIKKMIA--ETSSGGVTAN 388 Query: 519 DKCTGAVVSQQWFGGARMSGTDDKAGG 545 D V FGG SG G Sbjct: 389 DVIVHITVPTLPFGGVGNSGMGAYHGK 415 >1UXV-A nrPDB Length = 501 Score = 327 bits (838), Expect = 1e-89, Method: Composition-based stats. Identities = 115/536 (21%), Positives = 198/536 (36%), Gaps = 46/536 (8%) Query: 44 WDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVM 103 L ++K K P + GE +P + +A V + ++V Sbjct: 2 RAGLLEGVIKEKGGVPVYPSYLAGEW---GGSGQEIEVKSPIDLA-TIAKVISPSREEVE 57 Query: 104 NAVKAAKDAKKDW--YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEID 161 + + W ++P +R A+ KAAD+I + ++ GK A + Sbjct: 58 RTLDVLFK-RGRWSARDMPGTERLAVLRKAADIIE-RNLDVFAEVLVMNAGKP-KSAAVG 114 Query: 162 CITELSDFFRYYVKYASDLYAQQPV---ESADGTWNKAEYRPLEGFVYAVSPFNFTAI-A 217 + D R + R G V A++PFN+ A Sbjct: 115 EVKAAVDRLRLAELDLKKIGGDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDA 174 Query: 218 ANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLAD 277 N I + GN VV KPS + L + + L +AG P I + + ++++AD Sbjct: 175 VNKITYSFIYGNAVVVKPSISDPLPAAMAVKALLDAGFPPDAIALLNLPGKEA-EKIVAD 233 Query: 278 KDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVL 337 A+ FTGST V + + K + + E GG + +V A++ A Sbjct: 234 DRVAAVSFTGSTEVGERV----------VKVGGVKQYVMELGGGDPAIVLEDADLDLAAD 283 Query: 338 STIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRG 397 RG + + GQ+C A + + + ++ L S V Sbjct: 284 KIARGIYSYAGQRCDAIKLVLAERPVYGKLVEEVAKRLSSLRVGDPRDPT---------V 334 Query: 398 FMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIK---AKRPDHPY 454 +GP+I + D+++ IEDA + +L GG+ +V PT+++ + D Sbjct: 335 DVGPLISPSAVDEMMAAIEDAVEKGG-RVLAGGRRLGPT--YVQPTLVEAPADRVKDMVL 391 Query: 455 MSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGN 514 E F P+ E D ++ + + N Y L A+F +D I A L+ G Sbjct: 392 YKREVFAPVALAVEVKD--LDQAIE-LANGRPYGLDAAVFGRDVVKIRRAVRLLEV--GA 446 Query: 515 FYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELTDFKY 570 YIND + FGG + SG + G + + + N+ +KY Sbjct: 447 IYINDMPRHG-IGYYPFGGRKKSGVFREGIG-YAVEAVTAYKTIVFNYKGKGVWKY 500 >4I3V-A nrPDB Length = 488 Score = 325 bits (834), Expect = 3e-89, Method: Composition-based stats. Identities = 95/504 (18%), Positives = 189/504 (37%), Gaps = 46/504 (9%) Query: 62 PLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPF 121 P+ I G + ++ + N V+ V + A A + L Sbjct: 17 PMRIAGRLVDTDDRVEVRYPWN----DTVVGTVPAGRAEHAREAFAIAAAYQP---KLTR 69 Query: 122 YDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLY 181 Y+R I L A+ ++ + + ++ L G + + + + D F + Sbjct: 70 YERQKILLATAEALAAR-KEEISDVITLELGISKADSLYE-VGRAFDVFTLAGQMCIRDD 127 Query: 182 AQQP----VESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPS 236 + PL + A++PFN APA+ N VV KP+ Sbjct: 128 GEIFSCDLTPHGKARKIFTMREPLT-AISAITPFNHPLNMVAHKVAPAIATNNCVVVKPT 186 Query: 237 QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLY 296 + ++ LL +L EAGLP +++ + G P + +++ + + FTGS V K + Sbjct: 187 ELTPMTALLLADILYEAGLPPEMLSVVTGWPADIGMEMITNPHVDLVTFTGSVPVGKLI- 245 Query: 297 GKIQSGVVEGKYRDYPRIIGETGGKNFHLVHP---SANISHAVLSTIRGTFEFQGQKCSA 353 Y R + E GG + ++ +++ A + G + GQ+C+A Sbjct: 246 ---------AANAHYKRQVLELGGNDPLIILNDLSDDDLARAADLAVAGATKNSGQRCTA 296 Query: 354 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 413 R+ ES ++ F+ + + + +G VIHE++ + Sbjct: 297 VKRILCQESVADRFVPLVLERAKRLRFGDP---------MDRSTDLGTVIHEKAAALFEE 347 Query: 414 VIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTE 473 + A ++ + + G+ G + P V+ + E FGPI+ + PD Sbjct: 348 RVMRAAEEGADILYHPGR----SGALLPPIVVDRVPHQSDLVLEETFGPIIPIVRVPDD- 402 Query: 474 FNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGG 533 ++ + N++ + L+ + D + ++ LK N + + G + FGG Sbjct: 403 -DDATITLSNSTAFGLSSGVCTNDYRRMQKYIAGLKVGTVNIW---EVPGYRIEMSPFGG 458 Query: 534 ARMSGTDDKAGGPNILSRFVSIRN 557 + SG K G + F +++ Sbjct: 459 IKDSGNGYKEGVIEAMKSFTNVKT 482 >4H7N-A nrPDB Length = 474 Score = 310 bits (794), Expect = 1e-84, Method: Composition-based stats. Identities = 112/489 (22%), Positives = 179/489 (36%), Gaps = 34/489 (6%) Query: 72 DNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKA 131 N NP + + A+ A+ W L R + Sbjct: 1 SNAMTKTIEVRNPRTGKFDYVIIPPPPRLLAQQ-CNRARRAQSRWQELGVEGRITTLQQW 59 Query: 132 ADLISTKYRYDMLAATMLGQGK-NVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESAD 190 I ++ R + A + G+ ++ EID D R+ A +L ++ Sbjct: 60 KQAILSR-REQLTEALVNDTGRLSITVLEIDSFLASID--RWC-GLAPELLQTSAKNTSI 115 Query: 191 GTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-MGNTVVWKPSQTAALSNYLLMTV 249 + V +SP+NF + + PAL G VV KPS+ A L+ Sbjct: 116 PFIALQQSLVPYPLVGVISPWNFPLTLSMIDTIPALLAGCAVVVKPSEIAPRFVAPLLMA 175 Query: 250 LEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYR 309 L + V+ F+ G + ++ + FTGS + V E R Sbjct: 176 LNTVPELRDVLIFVEGGG-ETGANLINY--VDFVCFTGSVATGRE--------VAETAAR 224 Query: 310 DYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLS 369 + E GGK+ +V SAN+ A + + G GQ C + R+Y+ ESK EEF Sbjct: 225 RFIPAYLELGGKDPAIVLESANLELATSAILWGAVVNTGQSCLSIERIYVAESKFEEFYH 284 Query: 370 DMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYG 429 + + G +GP+I E+ + I DA + + I G Sbjct: 285 QLIAKAHRLQLA---------YPLVEDGAIGPIIAEKQAGIINDHILDAVEKGAV-IHCG 334 Query: 430 GQYDK-SQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYA 488 G+ ++ GW+ PTV+ M+ E FGPI+ V +PD E + N + Y Sbjct: 335 GKVEELGGGWWCRPTVMTNVNHSMKVMTEETFGPIMPVMPFPDV---EEAVYLANDTIYG 391 Query: 489 LTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMSGTDDKAGGPNI 548 L+ A+FA +L +AG IND A++ + SG G Sbjct: 392 LSAAVFAGSEDEALKVARQL--NAGAISINDAALTAMMHEGEKNAFNFSGLGGSRVGAAG 449 Query: 549 LSRFVSIRN 557 L RF+ + Sbjct: 450 LKRFLRKQA 458 >5UCD-A nrPDB Length = 457 Score = 306 bits (785), Expect = 1e-83, Method: Composition-based stats. Identities = 97/455 (21%), Positives = 172/455 (37%), Gaps = 40/455 (8%) Query: 108 AAKDAKKDWYNL-PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITEL 166 +A+ A R + + + + + +A GK ++ I + Sbjct: 35 SAQKAYFATRATADVGFRKQSLERLKEAVI-NNKEALYSALAEDLGKPKDVVDLAEIGAV 93 Query: 167 SDFFRYYVKYASDLYAQQPVESADGTWNKAEY--RPLEGFVYAVSPFNFTAIAANLIGAP 224 + + + + A V S D Y + G Y + PFN+ Sbjct: 94 LHEIDFALAHLDEWVAPVSVPSPDIIAPSECYVVQEPYGVTYIIGPFNYPVNLTLTPLIG 153 Query: 225 ALMG-NTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGAL 283 A++G NT + KPS+T ++ ++ ++ EA P+ V I G + + L F + Sbjct: 154 AIIGGNTCIIKPSETTPETSAVIEKIIAEAFAPEYV-AVIQGGRDE--NSHLLSLPFDFI 210 Query: 284 HFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGT 343 FTGS NV K V++ + ++ E GGK +V P A++ V + G Sbjct: 211 FFTGSPNVGK--------VVMQAAAKHLTPVVLELGGKCPLIVLPDADLDQTVNQLMFGK 262 Query: 344 FEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVI 403 F GQ A LY+ S + L + ++ + G ++ Sbjct: 263 FINSGQTXIAPDYLYVHYSVKDALLERLVERVK--------------TELPEINSTGKLV 308 Query: 404 HEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPI 463 E+ +LV ++E + +L G Q D S+ + TV+ + P MS E FGPI Sbjct: 309 TERQVQRLVSLLEATQGQ----VLVGSQADVSKRA-LSATVVDGVEWNDPLMSEELFGPI 363 Query: 464 LTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTG 523 L V E+ D ++ L +F KD + +++ +G+ +N Sbjct: 364 LPVLEFDSVRT--AIDQVNKHHPKPLAVYVFGKDMDVAKGIINQIQ--SGDAQVNGVMLH 419 Query: 524 AVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNT 558 A FGG SG + G + L+ F ++ Sbjct: 420 AFSPYLPFGGIGASGMGEYHGHFSYLT-FTHKKSV 453 >4QGK-A nrPDB Length = 461 Score = 305 bits (780), Expect = 4e-83, Method: Composition-based stats. Identities = 87/444 (19%), Positives = 170/444 (38%), Gaps = 39/444 (8%) Query: 106 VKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITE 165 V+ + A + P R ++ + + D+L A K+ + + Sbjct: 6 VRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREK-DILTAIAADLCKSEFNVYSQEVIT 64 Query: 166 LSDFFRYYVKYASDLYAQQPVESADGTWNKAEY-RP-LEGFVYAVSPFNFT--AIAANLI 221 + + ++ + +PV+ T Y +P G V + +N+ LI Sbjct: 65 VLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLI 124 Query: 222 GAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFG 281 GA A GN V+ KPS+ + + +L +L + L + + I G + T+ + + F Sbjct: 125 GAIA-AGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELL--KQRFD 180 Query: 282 ALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIR 341 + +TG+T V K V+E + + E GGK+ + ++ Sbjct: 181 HIFYTGNTAVGK--------IVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITW 232 Query: 342 GTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGP 401 G + GQ C A + S + + + ++ + S Sbjct: 233 GKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYER---------- 282 Query: 402 VIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFG 461 +I+ + F +++ ++E +I +GG+ D++ ++ PTV+ P M E FG Sbjct: 283 IINLRHFKRILSLLE------GQKIAFGGETDEAT-RYIAPTVLTDVDPKTKVMQEEIFG 335 Query: 462 PILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKC 521 PIL + + +E + I N + L +F+ + K I+ + + S+G ND Sbjct: 336 PILPIVPVKNV--DEAINFI-NEREKPLALYVFSHNHKLIKRMID--ETSSGGVTGNDVI 390 Query: 522 TGAVVSQQWFGGARMSGTDDKAGG 545 ++ FGG SG G Sbjct: 391 MHFTLNSFPFGGVGSSGMGAYHGK 414 >5NNO-A nrPDB Length = 546 Score = 261 bits (667), Expect = 6e-70, Method: Composition-based stats. Identities = 87/451 (19%), Positives = 167/451 (37%), Gaps = 37/451 (8%) Query: 106 VKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITE 165 V ++A D N R + +L+ + A + ++ + + I Sbjct: 21 VSKCREAFNDDANRDLKKRKQVLRSLLNLVEENT-DEFCKAIHRDRRRHRDETVVMEILP 79 Query: 166 LSDFFRYYVKYASDLYAQQPVESADGTWNK---AEYRPLEGFVYAVSPFNFTAIAANLIG 222 L + + +++ + +Y PL G V + +N+ + Sbjct: 80 LRNEVWHLIEHMDEYVKPVKPTMEGAAALDDCELQYEPL-GVVLVIGTWNYPLLLILQPL 138 Query: 223 APALM-GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFG 281 AL GNT V KPS+ A + LL +L + + V+ + G + T + + F Sbjct: 139 LGALAAGNTAVIKPSELAPATAELLTKLLPKY-VSSDVVGIVNGGVSETTAVL--KERFD 195 Query: 282 ALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA--NISHAVLST 339 + +TGS V + V+ + + E GGK+ +V + N+ Sbjct: 196 HILYTGSARVAE--------IVMAAAAKHLTPVTLELGGKSPVVVDDTCADNMKVVAERI 247 Query: 340 IRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQS------QNVVPMNTSASPISGG 393 + G GQ A + + +S + + ++ V+ Sbjct: 248 MWGKIINAGQTSIAPDYVVVEKSMESVLVDALAEARKAMLGDKFLKVLKGELLVKQKQQF 307 Query: 394 NLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHP 453 +++ F +L++ ++ K + GG+ D++ + PT++ P HP Sbjct: 308 LEESDYPRIVNASHFQRLMEFMKGGK------VAVGGEADEAT-LTIAPTILTNIDPTHP 360 Query: 454 YMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAG 513 M E FGPIL V Y + + +I II N+ + L +F+ +++ I + + S+G Sbjct: 361 VMQEEIFGPILPVLTYENEK--DILKII-NSREKPLALYVFSNNKRFIRGVES--RTSSG 415 Query: 514 NFYINDKCTGAVVSQQWFGGARMSGTDDKAG 544 +ND A FGG SG G Sbjct: 416 AVVVNDVVVHAGADGLPFGGVGRSGMGAYHG 446 >2Y53-A nrPDB Length = 534 Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats. Identities = 92/490 (18%), Positives = 170/490 (34%), Gaps = 57/490 (11%) Query: 57 SSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKD-AKKD 115 + + + G+ I T+P ++ ++ D+ A A++ Sbjct: 4 MTELLKNHVAGQWIAGTGAGITL--TDPVTGVALVRVSSEG--LDLARAFSFAREDGGAA 59 Query: 116 WYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVK 175 L + R+A L+ K R D A G + +D I YY K Sbjct: 60 LRALTYAQRAARLADIVKLLQAK-RGDYYAIATANSGTTRNDSAVD-IDGGIFTLSYYAK 117 Query: 176 --------YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM 227 +A + + + + P G ++ FNF + APAL+ Sbjct: 118 LGASLGEVHALRDGSAESLSKDRSFSAQHVLSPTRGVALFINAFNFPSWGLWEKAAPALL 177 Query: 228 -GNTVVWKPS-QTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHF 285 G V+ KP+ TA L+ ++ V++ LP G ++ I G + DQ+ + F + F Sbjct: 178 SGVPVIVKPATATAWLTQRMVADVVDAGILPPGALSIICGSSAGLLDQI---RSFDVVSF 234 Query: 286 TGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSA-----NISHAVLSTI 340 TGS + +L V G + N ++ A + + Sbjct: 235 TGSADTAATLRAHPAF-VQRGARLNVQADSL-----NSAILCADATPDTPAFDLFIKEVV 288 Query: 341 RGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMG 400 R GQKC+A R ++PE+ E L + L V + N MG Sbjct: 289 REMTVKSGQKCTAIRRAFVPEAALEPVLEALKAKLAKITVG---------NPRNDAVRMG 339 Query: 401 PVIHEQSFDKLVKVIEDAKKDP-------ELEILYGGQYDKSQGWFVGPTVIKAKRPDHP 453 ++ + ++ ++ I +++ + ++ D + V P + PD+ Sbjct: 340 SLVSREQYENVLAGIAALREEAVLAYDSSAVPLID---ADANIAACVAPHLFVVNDPDNA 396 Query: 454 --YMSTEFFGPILTVYEYPDTEFNEIC-----DIIDNTSQYALTGAIFAKDRKAIEYADE 506 E FGP+ +V Y T + Q +L +I++ D + Sbjct: 397 TLLHDVEVFGPVASVAPYRVTTDTNALPEAHAVALARRGQGSLVASIYSNDDAHLGRLAL 456 Query: 507 KLKFSAGNFY 516 +L S G + Sbjct: 457 ELADSHGRVH 466 >6D97-A nrPDB Length = 547 Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats. Identities = 108/546 (19%), Positives = 199/546 (36%), Gaps = 69/546 (12%) Query: 56 SSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKD 115 SS EV + G N +P N + + V + ++ + +++ K Sbjct: 40 SSPAEVQNFVQGSWTASAN---WNWIVDPLNGDKFI-KVAEVQGTEIKSFMESLSKCPKH 95 Query: 116 WYNLP--FYDR----SAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDF 169 + P +R I KAA ++ D A + YQ + + F Sbjct: 96 GLHNPLKAPERYLMYGDISAKAAHMLGQPTVLDFFAKLIQRVSPKSYQQALAEVQVSQKF 155 Query: 170 FRYYVKYASDLYAQQ-PVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPAL-M 227 + A+ V YR G V ++PFNF L AL M Sbjct: 156 LENFCGDQVRFLARSFAVPGNHLGQRSNGYRWPYGPVAIITPFNFPLEIPLLQLMGALYM 215 Query: 228 GNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTG 287 GN V K ++ ++ +L + GLP ++FI D V +++L + + FTG Sbjct: 216 GNKPVLKVDSKVSIVMEQMIRLLHDCGLPAEDMDFINSDGA-VMNKLLLEANPKMTLFTG 274 Query: 288 STNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSAN-ISHAVLSTIRGTFEF 346 S+ V + L ++ R+ E G ++ ++ P + + + + Sbjct: 275 SSRVAEKLAADLKG-----------RVKLEDAGFDWKILGPDVQEVDYVAWVCDQDAYAC 323 Query: 347 QGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQ 406 GQKCSA S L++ ++ S L + L + + T +GPV+ Sbjct: 324 SGQKCSAQSVLFMHKNWSSSGLLEKMKKLSERRKLEDLT-------------IGPVLTVT 370 Query: 407 SFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDH-------------- 452 + + +++ + + K ++L+GG+ + P + A +P Sbjct: 371 T-EAMIEHMNNLLKIRGSKVLFGGEPLANHSI---PKIYGAMKPTAVFVPLEEILKSGNF 426 Query: 453 PYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSA 512 ++ E FGP V EY + + + + + + + LT AI + D ++ + Sbjct: 427 ELVTKEIFGPFQVVTEYSEDQLELVLEACERMNAH-LTAAIVSNDPLFLQDVLG--RSVN 483 Query: 513 GNFY--INDKCTGAVVSQQWFGGARMSGTDDKAGGPNILSRFVSIRNTKENFYELT---- 566 G Y I + TGA WFG A G P + + +E Y++ Sbjct: 484 GTTYAGIRARTTGA-PQNHWFGPAGDP-RGAGIGTPEAIK--LVWSCHREIIYDVGPVPE 539 Query: 567 DFKYPS 572 + PS Sbjct: 540 SWALPS 545 >3V4C-A nrPDB Length = 528 Score = 161 bits (407), Expect = 8e-40, Method: Composition-based stats. Identities = 89/519 (17%), Positives = 147/519 (28%), Gaps = 76/519 (14%) Query: 47 LRASLMKFKSSSLEVP---LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVM 103 L + F+S + P ++ GE + A P PA+ + T + V Sbjct: 13 LGTENLYFQSMMIFTPKGKHLVAGEWLDGAGTFASAPAHGPAH------DFAVGTVELVN 66 Query: 104 NAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCI 163 A +AA++A + +R+A AD I + + G + + Sbjct: 67 RACEAAEEAFWTYGYSSRKERAAFLRAIADEIEARAEA-ITEIGSQETGLPEARLNGER- 124 Query: 164 TELSDFFRYYVKYA-------SDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAI 216 + R + + + A P + G V NF Sbjct: 125 GRTTGQLRLFADHIEKGDYLDRRVDAAMPERQPAPRQEIRLVQRPVGPVAVFGASNFPLA 184 Query: 217 AANL---IGAPALMGNTVVWKPSQTAALSNYLLMTVLEEA----GLPKGVINFIPGDPVQ 269 + A G VV K + ++ ++ A G+ GV + I G Sbjct: 185 FSTAGGDTAAALAAGCPVVVKGHSAHPGTGEIVAEAVDAAIRKTGVHPGVFSLIQGGSRD 244 Query: 270 VTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPS 329 V ++ A+ FTGS ++L+ + GE G N + P Sbjct: 245 VGHALVQHPHIKAVGFTGSLAGGRALFDLCA------ARPEPIPFFGELGSVNPMFLLPE 298 Query: 330 ANISHAV---LSTIRGTFEFQGQKCSAASRLYLPESK-SEEFLSDMFGILQSQNVVPMNT 385 A + A GQ C+ + E ++ F + L M T Sbjct: 299 ALKARAETLGQGWAGSLTMGAGQFCTNPGIAVVIEGADADRFTTAAVEALAKVAPQTMLT 358 Query: 386 SASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYD-----KSQGWFV 440 I A +D + +S G Sbjct: 359 DG---------------------------IAKAYRDGQARFATRNAVKPLLATESSGRDA 391 Query: 441 GPTVIKAKRPD---HPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYALTGAIF--A 495 P + + + E FGP+ V + + Q LT I A Sbjct: 392 SPNLFETTGAQFLADHALGEEVFGPLGLVVRVGS---PAEMEELARGFQGQLTATIHMDA 448 Query: 496 KDRKAIEYADEKLKFSAGNFYINDKCTGA-VVSQQWFGG 533 D + L+ AG +N TG VV GG Sbjct: 449 GDLETARRLRPVLERKAGRVLVNGFPTGVEVVDSMVHGG 487 >1EZ0-A nrPDB Length = 510 Score = 128 bits (321), Expect = 8e-30, Method: Composition-based stats. Identities = 80/478 (16%), Positives = 158/478 (33%), Gaps = 53/478 (11%) Query: 77 ALFPQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLIS 136 +F TN + + TE +V A AA +D+ L R+++ A + Sbjct: 7 NVFYATNAFTGEALPLAFPVHTEVEVNQAATAAAKVARDFRRLNNSKRASLLRTIASELE 66 Query: 137 TKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD-------LYAQQPVESA 189 + D++A L + I ++ R + + L P + Sbjct: 67 ARS-DDIIARAHLETALPEVR-LTGEIARTANQLRLFADVVNSGSYHQAILDTPNPTRAP 124 Query: 190 DGTWNKAEYRPLEGFVYAVSPFNFTAIAANL---IGAPALMGNTVVWKPSQTAALSNYLL 246 + + G V NF + + G V+ K ++ ++ Sbjct: 125 LPKPDIRRQQIALGPVAVFGASNFPLAFSAAGGDTASALAAGCPVIVKGHTAHPGTSQIV 184 Query: 247 MTVLEEA----GLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSG 302 +E+A LP+ + + G+ + +++ + A+ FTGS ++L+ Sbjct: 185 AECIEQALKQEQLPQAIFTLLQGNQRALGQALVSHPEIKAVGFTGSVGGGRALFNLAHER 244 Query: 303 VVEGKYRDYPRIIGETGGKNFHLVHPSANISHA--VLSTIRGTFEFQGQKCSAASRLYLP 360 + GE G N + PSA + A + GQ C+ ++ Sbjct: 245 ------PEPIPFYGELGAINPTFIFPSAMRAKADLADQFVASMTMGCGQFCTKPGVVFAL 298 Query: 361 E-SKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDAK 419 +++ F+ +Q+++ + ++ ++ G + V+ S D I+ Sbjct: 299 NTPETQAFIE------TAQSLIRQQSPSTLLTPGIRDSYQSQVVSRGSDD----GIDVTF 348 Query: 420 KDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGP-ILTVYEYPDTEFNEIC 478 E + + S + HP E FGP L V + + Sbjct: 349 SQAESPCVASALFVTSSENW----------RKHPAWEEEIFGPQSLIVVCENVADMLSLS 398 Query: 479 DIIDNTSQYALTGAIFAK--DRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW-FGG 533 +++ + LT I A D + +L+ AG N TG V GG Sbjct: 399 EMLAGS----LTATIHATEEDYPQVSQLIPRLEEIAGRLVFNGWPTGVEVGYAMVHGG 452 >3K9D-A nrPDB Length = 464 Score = 120 bits (302), Expect = 1e-27, Method: Composition-based stats. Identities = 54/282 (19%), Positives = 99/282 (35%), Gaps = 22/282 (7%) Query: 98 TEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQ 157 + ++V N +++A A+K+ + I AD R + G ++Q Sbjct: 10 SIQEVRNLIESANKAQKELAAMSQQQIDTIVKAIADAGYG-AREKLAKMAHEETGFGIWQ 68 Query: 158 AEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSP-FNFTAI 216 ++ S Y+K + + D E G V + P N T+ Sbjct: 69 DKVIKNVFASKHVYNYIKDMKTIGMLKE----DNEKKVMEVAVPLGVVAGLIPSTNPTST 124 Query: 217 AANLIGAPALMGNTVVWKPSQTAAL----SNYLLMTVLEEAGLPKGVINFIPGDPVQVTD 272 GN++V+ P A + ++ E+AG PKG I+ + +Q TD Sbjct: 125 VIYKTLISIKAGNSIVFSPHPNALKAILETVRIISEAAEKAGCPKGAISCMTVPTIQGTD 184 Query: 273 QVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANI 332 Q++ KD + TG + + K+ Y + G G + SANI Sbjct: 185 QLMKHKDTAVILATGGSAMVKAAYSSGTPAIGVGP------------GNGPAFIERSANI 232 Query: 333 SHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGI 374 AV + G C++ + + E +++ Sbjct: 233 PRAVKHILDSKTFDNGTICASEQSVVVERVNKEAVIAEFRKQ 274 >5UJU-A nrPDB Length = 576 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 90/551 (16%), Positives = 177/551 (32%), Gaps = 95/551 (17%) Query: 41 LKDWDLLRASLMKFKSSSLEVPLVI-------------NGERIYDNNERALFPQTNPANH 87 K D L+ +L +S P +GE + ++ F PA+ Sbjct: 15 TKHEDTLKRALAAIESRGYWSPFAEMPSPKVYGESGNADGEAAFKSHLGKTFELDQPASG 74 Query: 88 QQVLAN-VTQATEKDV-------MNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKY 139 + V A D+ + AA A++ W + L+ + + Sbjct: 75 ETVGAERSPYGVALDIRYPKSTPDALIAAAAAAQRTWREAGPSAWIGVSLEILARL-NRA 133 Query: 140 RYDMLAATMLGQGKNVYQA-----------EIDCITELSDFFRYYVKYASDLYAQQPVES 188 +++ + M G+ A ++ + D R + +D + ++P Sbjct: 134 SFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDQLR---RIPADAHWEKPQGK 190 Query: 189 ADGTWNKAEYRPL---EGFVYA---VSPFN-FTAIAANLIGAPALMGNTVVWKPSQTAAL 241 + Y + G V +N + + A GNTV+ KP A L Sbjct: 191 NPPLAMQKRYTIVPRGTGLVLGCCTFPTWNGYPGL-----FADLATGNTVIVKPHPGAIL 245 Query: 242 SNYLLMTV----LEEAGLPKGVINFI---PGDPVQVTDQVLADKDFGALHFTGSTNVFKS 294 + + + L EAG V+ + P D V D + + + FTGST Sbjct: 246 PLAITVRIARDVLREAGFDPNVVTLLATEPNDGALVQD-LALRPEIKLIDFTGSTQNGTW 304 Query: 295 LYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAA 354 L ++ E G N ++ + ++ A + + GQ C+A Sbjct: 305 LERHA----------HQAQVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLALYSGQMCTAP 354 Query: 355 SRLYLPES--KSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLV 412 +Y+P ++ + + + Q+ + P +I D + Sbjct: 355 QNIYVPRDGIRTADGHASFDEVAQAIAGAVQKLTGDPARSVE-------LIGAIQNDGVT 407 Query: 413 KVIEDAKKDPELEILYGGQYDKSQGW----FVGPTVIKAKRPDHPYMSTEFFGPILTVYE 468 I+ A+ +L Q + + P V++ D + E+FGPI V Sbjct: 408 ARIDAARAVG--RVLLDSQTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIA 465 Query: 469 YPDTE--FNEICDIIDNTSQYA-LTGAIFA--KD-RKAIEYADEKLKFS-----AGNFYI 517 T + +I ++ LT ++++ D A A + + G ++ Sbjct: 466 TDSTAQSLDLAGEIAA---EHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFV 522 Query: 518 NDKCTGAVVSQ 528 N + Sbjct: 523 NQSAAFSDFHG 533 >5J7I-A nrPDB Length = 488 Score = 117 bits (293), Expect = 1e-26, Method: Composition-based stats. Identities = 86/470 (18%), Positives = 159/470 (33%), Gaps = 73/470 (15%) Query: 85 ANHQQVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKY-RYDM 143 ++ +L ++ + ++V N ++ AK A+K + + I A+ + R Sbjct: 19 SHMASMLRDIDLQSIQEVRNYLEEAKAAQKILEKMTQSEIDKIVESMANAAREEAGRLAA 78 Query: 144 LAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEG 203 +A G G NV + + +D + D+ + + +P+ G Sbjct: 79 MAVEETGFG-NVEDKTLKNLFAANDVYN----SIKDVKTVGIIRRDEENRVWEIAQPV-G 132 Query: 204 FVYAVSP-FNFTAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEA----GLPKG 258 V + P N T+ N +V+ P +AA +++EA G PKG Sbjct: 133 IVAGIIPSTNPTSTVIFKALIAVKARNAIVFSPHPSAAKCTAEAARIMQEAAERAGAPKG 192 Query: 259 VINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGET 318 +I+ I + T++++ K + TG + K+ Y + G Sbjct: 193 LISCITQPTMAATNELMKHKLTDVILATGGPGLVKAAYSSGKPAYGVGP----------- 241 Query: 319 GGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQ 378 G +H SANI+ AV I+ G C++ L + ES E+ ++++ Sbjct: 242 -GNVPVYIHESANIAKAVQLIIQSKTFDYGTICASEQALLVDESIKEKVVAELKQQGAY- 299 Query: 379 NVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVI-----EDAKKDPELEILYGGQYD 433 ++E+ K+ +I +AK + + Sbjct: 300 -----------------------FLNEEEKQKVASIIMVNGSLNAKIVGKAPQV----IA 332 Query: 434 KSQGWFVGPTVIKAKRPDHPYMSTEFF-----GPILTVYEYPD-TEFNEICDIIDNTSQY 487 + G + V + F PIL Y E +E+ + Sbjct: 333 EMAGIEIPSDVKLLVAEETEVGKEYPFSIEKLSPILAFYIVKGMEEASELAQKLLEVGGL 392 Query: 488 ALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARMS 537 T I A+D K IE + AG +N T FGG + Sbjct: 393 GHTVGIHAEDEKVIE--AYTIDKPAGRIVVNAGTT--------FGGIGAT 432 >3MY7-A nrPDB Length = 452 Score = 113 bits (284), Expect = 2e-25, Method: Composition-based stats. Identities = 64/447 (14%), Positives = 145/447 (32%), Gaps = 49/447 (10%) Query: 94 VTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGK 153 + ++ + K A++++ ++ +AA L + + R + + G Sbjct: 1 MPVTNMAELDAMIARVKKAQEEFATYS-QEQVDKIFRAASLAANQARIPLAQQAVEESGM 59 Query: 154 NVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNF 213 + + ++ S+F Y KY + +E D P+ V N Sbjct: 60 GIVEDKVIKNHFASEFI--YNKYKDE-QTCGILEEDDNLGTMTIAEPVGIICGIVPTTNP 116 Query: 214 TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEA----GLPKGVINFIPGDPVQ 269 T+ A N +++ P A S ++ +A G PK +I +I V+ Sbjct: 117 TSTAIFKSLISLKTRNGIIFSPHPRAKNSTNDAAKLVLDAAVAAGAPKDIIGWIDQPSVE 176 Query: 270 VTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPS 329 +++ ++ D + TG + K+ Y + + G G ++ + Sbjct: 177 LSNALMKHDDIALILATGGPGMVKAAYSSGKPAIGVGA------------GNVPVVIDET 224 Query: 330 ANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASP 389 A+I AV S + G C++ + + + +E S ++ + + Sbjct: 225 ADIKRAVASVLMSKTFDNGVVCASEQAVIVVDEVYDEVKERF----ASHKAHVLSKTDAD 280 Query: 390 ISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKD-PELEILYGGQYDKSQGWFVGPTVIKAK 448 L +I K+V A + +++ + +G + Sbjct: 281 KVRKVL------LIDGALNAKIVGQPATAIAEMAGVKVPADTKVLIGEG-------LGKV 327 Query: 449 RPDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQ---YALTGAIFAK---DRKAIE 502 D + + P L ++ + F + + T ++ + I Sbjct: 328 SYDDAFAHEKL-SPTLGMFRADN--FEDAVAQAVTMVEIGGIGHTSGLYTNQDVNADRIR 384 Query: 503 YADEKLKFSAGNFYINDKCTGAVVSQQ 529 Y +K+K + IN T + Sbjct: 385 YFGDKMKTAR--ILINIPTTHGGIGDL 409 >5DBV-A nrPDB Length = 445 Score = 103 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 68/444 (15%), Positives = 135/444 (30%), Gaps = 61/444 (13%) Query: 100 KDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTK--YRYDMLAATMLGQGKNVYQ 157 D+ A++AAK+A+ + R K I K + LA + + Sbjct: 16 DDMNQAIEAAKEAQLVVKKMSMDQR----EKIISAIRKKTIEHAETLARMAVE------E 65 Query: 158 AEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSP-FNFTAI 216 + + + + + G + A++P N + Sbjct: 66 TGMGNVGHKILKHQLVAEKTPGTEDITTTAWSGDRGLTLVEMGPFGVIGAITPCTNPSET 125 Query: 217 AANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKG-VINFIPGDPVQVTDQ-- 273 GNTVV+ P A ++ + ++ EA L G +N D Sbjct: 126 IICNTIGMLAGGNTVVFNPHPAAIKTSNFAVQLINEASLSAGGPVNIACSVRKPTLDSSK 185 Query: 274 -VLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANI 332 +++ +D + TG V ++ + G+ G G LV +A+I Sbjct: 186 IMMSHQDIPLIAATGGPGVVTAVLQSGKRGIGAGA------------GNPPVLVDETADI 233 Query: 333 SHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISG 392 A I G A + ++ + E ++ M I+ Sbjct: 234 RKAAEDIINGCTFDNNLPAIAEKEVVAIDAIANELMNYMVK----------EQGCYAITK 283 Query: 393 GNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYG-GQYDKSQGWFVGPTVIKAKRPD 451 VI + ++ + +L G S + + + ++ + Sbjct: 284 EQQEKLTNLVITPKGLNR------NCVGKDARTLLGMIGIDVPSN---IRCIIFEGEK-E 333 Query: 452 HPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYAL--TGAIFAKDRKAIEYADEKLK 509 HP +S E PIL + F++ + ++ + I +K+ I + + Sbjct: 334 HPLISEELMMPILGIVRAKS--FDDAVEKAV-WLEHGNRHSAHIHSKNVDRITTYAKAI- 389 Query: 510 FSAGNFYINDKCTGAVVSQQWFGG 533 N A+ FGG Sbjct: 390 -DTAILVKNAPSYAAIG----FGG 408 >5JFN-A nrPDB Length = 524 Score = 99.3 bits (246), Expect = 4e-21, Method: Composition-based stats. Identities = 57/427 (13%), Positives = 131/427 (30%), Gaps = 56/427 (13%) Query: 120 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 179 DR+ D+I + + ++ + + + R + Sbjct: 112 SMSDRARFVQGIRDVILNQDTLEKMSRMAVE------ETGMGNYEHKLIKNRLAGEKTPG 165 Query: 180 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPF-NFTAIAANLIGAPALMGNTVVWKPSQT 238 + + G + A++P N T GN+VV+ P Sbjct: 166 IEDLTTDAFSGDNGLTLVEYSPFGVIGAITPTTNPTETIVCNSIGMLAAGNSVVFSPHPR 225 Query: 239 AALSNYLLMTVLEE----AGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKS 294 A + LL+ ++ + G P+ ++ + ++ T+ ++A L TG + K+ Sbjct: 226 ARQVSLLLVRLINQKLAALGAPENLVVTVEKPSIENTNAMMAHPKVRMLVATGGPAIVKA 285 Query: 295 LYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAA 354 + + + G G +V +ANI A + G A Sbjct: 286 VLSTGKKAIGAGA------------GNPPVVVDETANIEKAACDIVNGCSFDNNLPXVAE 333 Query: 355 SRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIH--EQSFDKLV 412 + ++ + ++ + P + L GP +S L+ Sbjct: 334 KEIIAVAQIADYLIFNLKKNGAYEIKDP--AVLQQLQDLVLTAKGGPQTKCVGKSAVWLL 391 Query: 413 KVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYP-- 470 I + D ++I ++ +HP++ E PIL + Sbjct: 392 SQIGISV-DASIKI-----------------ILMEVPREHPFVQEELMMPILPLVRVETV 433 Query: 471 DTEFNEICDIIDNTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQW 530 D + ++ + T + + D + + + ++ ++ + + A + Sbjct: 434 DDAIDLAIEVEHDNRH---TAIMHSTDVRKLTKMAKLIQT---TIFVKNGPSYAGLGA-- 485 Query: 531 FGGARMS 537 GG S Sbjct: 486 -GGEGYS 491 >1O20-A nrPDB Length = 427 Score = 77.7 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 58/351 (16%), Positives = 119/351 (33%), Gaps = 50/351 (14%) Query: 102 VMNAVKAAKDAKKDW---YNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKN---- 154 + ++ AK ++ W N +++ K A+ + + R ++L A + K Sbjct: 13 MDELLEKAKKVREAWDVLRNATTREKNKAIKKIAEKLDER-RKEILEANRIDVEKARERG 71 Query: 155 VYQAEIDC-------ITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYA 207 V ++ +D I E+ + + + A R G + Sbjct: 72 VKESLVDRLALNDKRIDEMIKACETVIGLKDPVGEVIDSWVREDGLRIARVRVPIGPIGI 131 Query: 208 VSPFNF---TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLM----TVLEEAGLPKGVI 260 + + + GNT++ + A SN ++ L+E +P+ + Sbjct: 132 I----YESRPNVTVETTILALKSGNTILLRGGSDALNSNKAIVSAIREALKETEIPESSV 187 Query: 261 NFI-PGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETG 319 FI D V + + + + + G++ + + ETG Sbjct: 188 EFIENTDRSLVLEMIRLREYLSLV------------IPRGGYGLISFVRDNATVPVLETG 235 Query: 320 -GKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQ 378 G V SA++ AV I + G C+AA +L + E ++EFL + L+ Sbjct: 236 VGNCHIFVDESADLKKAVPVIINAKTQRPG-TCNAAEKLLVHEKIAKEFLPVIVEELRKH 294 Query: 379 NVVPMN--------TSASPISGGN-LRGFMGPVIHEQSFDKLVKVIEDAKK 420 V P + + ++ +I + + + IE KK Sbjct: 295 GVEVRGCEKTREIVPDVVPATEDDWPTEYLDLIIAIKVVKNVDEAIEHIKK 345 >4GHK-A nrPDB Length = 444 Score = 70.4 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 74/480 (15%), Positives = 134/480 (27%), Gaps = 109/480 (22%) Query: 108 AAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELS 167 AAK+A L R+ I A L + R A K + A +D +T Sbjct: 48 AAKNA-----ALEAVARA-IERDAGALKAANARDVARAKD-----KGLDAAFVDRLTLSD 96 Query: 168 DFFRYYVKYASDLYAQQPVESADGTWNKAEYRP----------LEGFVYAVSPFNFTAIA 217 + V+ + + G + +YRP G + + + + Sbjct: 97 KALKTMVEGLRQVAT---LPDPIGEMSNLKYRPSGIQVGQMRVPLGVIGII----YESRP 149 Query: 218 ANLIGAPALM---GNTVVWKPSQTAALSNYLLMTV----LEEAGLPKGVINFI-PGDPVQ 269 I A AL GN + + A SN L + L EAGLP+ + + D Sbjct: 150 NVTIDAAALCLKSGNATILRGGSEALESNTALAKLIGEGLAEAGLPQDTVQVVETADRAA 209 Query: 270 VTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNFHLVHPS 329 V + + + KSL ++ + + G V Sbjct: 210 VGRLITMTEYVDVIV----PRGGKSLIERLINEARVPMIKH-------LDGICHVYVDDR 258 Query: 330 ANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASP 389 A+++ A+ G C+ L + + LS + + + + + Sbjct: 259 ASVTKALTVCDNAKTHRYG-TCNTMETLLVARGIAPAVLSPLGRLYREK--GVELRVDAD 315 Query: 390 ISGGNLRGFMGPVIHEQSFDKLVKVIEDAKKDPELEILYGGQYDKSQGWFVGPTVIKAKR 449 +GP++ D Sbjct: 316 ARAVLEAAGVGPLVDATDED---------------------------------------- 335 Query: 450 PDHPYMSTEFFGPILTVYEYPDTEFNEICDIIDNTSQYAL--TGAIFAKDRKAIEYADEK 507 TE+ P+L + + + I+ +Y T AI +D + Sbjct: 336 -----WRTEYLAPVLAIKIVDG--IDAAIEHIN---EYGSHHTDAIVTEDHDRAMRFLRE 385 Query: 508 LKFSAGNFYINDKCTGAVVSQQWFG-G--ARMSGTDDKAGGPNILSRFVSIRNTKENFYE 564 + ++ + FG G +S A GP L S++ E Sbjct: 386 VDSASVMVN----ASTRFADGFEFGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGHGE 441 >4JBE-A nrPDB Length = 445 Score = 63.5 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 64/356 (17%), Positives = 115/356 (32%), Gaps = 48/356 (13%) Query: 95 TQATEKDVMNAVK----AAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLG 150 + A +V AV+ AAK A P A AD + +R +LAA Sbjct: 30 SNAMTNEVAKAVEECARAAKSAAPSLSGAPDTAIDAALESMADRLLA-HRDAVLAANAED 88 Query: 151 QGK--------------NVYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKA 196 K + ++ + T+++D R A + + DG Sbjct: 89 IAKAEAGGMSAGLLDRLTITESRL---TDMADQLRLLAG-APHPQRTVELSTLDGGLRLV 144 Query: 197 EYRPLEGFVYAVSPFNFTA-IAANLIGAPALMG--NTVVWKPSQTAALSNYLLMTV---- 249 E R G + A N+ A + A L+ N V + A S L+ V Sbjct: 145 ERRRPVGVIGA----NYEARPNVTVDVASQLVKSRNAGVLRTGSAALKSAQRLLEVVIRP 200 Query: 250 -LEEAGLPKGVINFIPGDPVQVTDQVLADKD-FGALHFTGSTNVFKSLYGKIQSGVVEGK 307 L ++G+ V+ +P + ++ D + GS G+ + Sbjct: 201 ALTDSGIDANVVQLVPRPEREAAGALVRLPDLVPLVILRGS--------GESTRALALEA 252 Query: 308 YRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPESKSEEF 367 + R + G V A+ V S + + + G C+ + L + ++ EEF Sbjct: 253 AQHGVRTLAHADGGGVLYVDEKADRD-TVRSLVVNSLDRLG-VCNRLNLLLIHDAVYEEF 310 Query: 368 LSDMFGILQSQNVVPMNTSASPISGGN--LRGFMGPVIHEQSFDKLVKVIEDAKKD 421 + L + V P G L + D + + + A ++ Sbjct: 311 WPVVSEALAERGVSPSLPPYDHPIGYEWALDSEREATVTVARVDGVAEAVRIANEE 366 >1VLU-A nrPDB Length = 468 Score = 56.9 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 43/291 (14%), Positives = 86/291 (29%), Gaps = 43/291 (14%) Query: 106 VKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLA-----ATMLGQG------KN 154 K A+ A + RS I K D + A A G K Sbjct: 20 AKNARKAGNILKTISNEGRSDILYKIHDALKANAHAIEEANKIDLAVAKETGLADSLLKR 79 Query: 155 VYQAEIDCITELSDFFRYYVKYASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNF- 213 + + D + + + + + D + G + + F Sbjct: 80 LDLFKGDKFEVMLQGIKDVAELEDPVGKVKMARELDDGLTLYQVTAPVGVLLVI----FE 135 Query: 214 --TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLE--------EAGLPKGVINFI 263 + AN+ GN + K + + + + ++ E G+P G + I Sbjct: 136 SRPEVIANITALSIKSGNAAILKGGKESVNTFREMAKIVNDTIAQFQSETGVPVGSVQLI 195 Query: 264 PGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETGGKNF 323 V+D + D+ + GS + + + + V+ G Sbjct: 196 E-TRQDVSDLLDQDEYIDLVVPRGSNALVRKIKDTTKIPVLGHAD-----------GICS 243 Query: 324 HLVHPSANISHAVLSTIRGTFEF-QGQKCSAASRLYLPE--SKSEEFLSDM 371 + A++ A ++ + G C+A L + SK E L ++ Sbjct: 244 IYLDEDADLIKAKRISLDAKTNYPAG--CNAMETLLINPKFSKWWEVLENL 292 >2H5G-A nrPDB Length = 463 Score = 55.4 bits (132), Expect = 6e-08, Method: Composition-based stats. Identities = 60/352 (17%), Positives = 111/352 (31%), Gaps = 53/352 (15%) Query: 102 VMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEID 161 V + A+ + L R+ I ADL++ + +LA K++ +AE Sbjct: 31 VEQQGEMARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLA-----NKKDLEEAEGR 85 Query: 162 CITELSDFFRYYVKYASDLYA--QQPVESADGTWNKAEYR-------------PLEGFVY 206 L + L +Q S+ + + R G + Sbjct: 86 LAAPLLKRLSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLL 145 Query: 207 AVSPFNFTAIAANLIGAPALM---GNTVVWKPSQTAALSNYLLMTVLEEA----GLPKGV 259 + F + L AL GN ++ K + AA SN +L + +EA G+ K Sbjct: 146 VI----FESRPDCLPQVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGV-KEA 200 Query: 260 INFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGKIQSGVVEGKYRDYPRIIGETG 319 + + +V D DK + GS+ + + + + V G Sbjct: 201 VQLVN-TREEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKGIPVMGHSE---------- 249 Query: 320 GKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLYLPES-----KSEEFLSDMFGI 374 G V A++ E+ C+A L + ++ + + Sbjct: 250 GICHMYVDSEASVDKVTRLVRDSKCEYPA-ACNALETLLIHRDLLRTPLFDQIIDMLRVE 308 Query: 375 LQSQNVVPMNTS---ASPISGGNLRGFMGPV-IHEQSFDKLVKVIEDAKKDP 422 + P S SP +LR G + + + D + I+ K Sbjct: 309 QVKIHAGPKFASYLTFSPSEVKSLRTEYGDLELCIEVVDNVQDAIDHIHKYG 360 >1PDZ-A nrPDB Length = 434 Score = 37.3 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 19/121 (15%), Positives = 44/121 (36%), Gaps = 8/121 (6%) Query: 251 EEAGLPKGVINFIPGDPVQVTDQVLADK----DFGALHFTGSTNVFKSLYGKIQSGVVEG 306 +E LP N I G +++ + GA FT + + +Y +++ + Sbjct: 141 DEVILPVPAFNVING-GSHAGNKLAMQEFMILPTGATSFTEAMRMGTEVYHHLKAVIKAR 199 Query: 307 KYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCS--AASRLYLPESKS 364 D + E GG ++++ + + + + + + AAS Y + Sbjct: 200 FGLDATAVGDE-GGFAPNILNNKDALDLIQEAIKKAGYTGKIEIGMDVAASEFYKQNNIY 258 Query: 365 E 365 + Sbjct: 259 D 259 >4YIF-A nrPDB Length = 164 Score = 36.1 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 10/58 (17%) Query: 83 NPANHQQVLANVTQATEKDVMNAVKAAKDAKKDW-----YNLPFYDRSAIFLKAADLI 135 +P + +QVL +V+++ + VKAA+ A+++W L +R I AADL+ Sbjct: 104 HPIDGRQVLVSVSESGAEL----VKAARRARQEWLAERLATLNRSER-DILRSAADLM 156 >3BA0-A nrPDB Length = 365 Score = 32.7 bits (73), Expect = 0.48, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 17/41 (41%), Gaps = 3/41 (7%) Query: 95 TQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLI 135 +DV A+ + A + W N+ S I AD++ Sbjct: 18 PDMNREDVDYAI---RKAFQVWSNVTPLKFSKINTGMADIL 55 >1JIZ-A nrPDB Length = 166 Score = 32.7 bits (73), Expect = 0.50, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 17/41 (41%), Gaps = 3/41 (7%) Query: 95 TQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLI 135 +DV A+ + A + W N+ S I AD++ Sbjct: 25 PDMNREDVDYAI---RKAFQVWSNVTPLKFSKINTGMADIL 62 >3QTP-A nrPDB Length = 441 Score = 32.3 bits (72), Expect = 0.54, Method: Composition-based stats. Identities = 22/136 (16%), Positives = 51/136 (37%), Gaps = 13/136 (9%) Query: 219 NLIGAPALMGNTVVW---KPSQTAALSNYLLMTVL--EEAGLPKGVINFIPGDPVQVTDQ 273 +GA A++G ++ ++ L + +E +P N I G + Sbjct: 107 GKLGANAILGCSMSICRAAAAEKGLPLYKYLAELTGHKEMTMPVPCFNVING-GAHAGNA 165 Query: 274 VLADKDFGALHFTGSTNVFKSLYGKIQS-----GVVEGKYRDYPRIIGETGGKNFHLVHP 328 + + + TG+TN ++L ++ V++ KY +G+ GG ++ Sbjct: 166 LAMQEF--MICPTGATNFHEALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGA 223 Query: 329 SANISHAVLSTIRGTF 344 + V + + + Sbjct: 224 REALDLLVEAIAKAGY 239 >5MMM-i nrPDB Length = 208 Score = 31.9 bits (71), Expect = 0.83, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 19/53 (35%) Query: 214 TAIAANLIGAPALMGNTVVWKPSQTAALSNYLLMTVLEEAGLPKGVINFIPGD 266 P + N V KP A S + V E A L K V + +PG Sbjct: 25 PQTLPMARTKPFSLSNPAVVKPLVITATSATAPVEVAETADLEKFVKSRLPGG 77 >3UJR-A nrPDB Length = 443 Score = 31.9 bits (71), Expect = 0.85, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 34/94 (36%), Gaps = 6/94 (6%) Query: 255 LPKGVINFIPGDPVQVTDQVLADK----DFGALHFTGSTNVFKSLYGKIQSGVVEGKYRD 310 LP N I G +++ + GA F + + +Y ++ + + +D Sbjct: 144 LPVPAFNVING-GSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKD 202 Query: 311 YPRIIGETGGKNFHLVHPSANISHAVLSTIRGTF 344 + E GG +++ S + + + + Sbjct: 203 ATNVGDE-GGFAPNILENSEALELVKEAIDKAGY 235 >4UYA-A nrPDB Length = 340 Score = 31.9 bits (71), Expect = 0.87, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 29/79 (36%), Gaps = 12/79 (15%) Query: 424 LEILYGGQYDKS-QGWFVGPTVIKA----KRPDHPYMSTEFFGPILT-------VYEYPD 471 LE GG +++ G + P V+ Y+ E F PIL + Sbjct: 104 LEFARGGALNRALAGRRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEK 163 Query: 472 TEFNEICDIIDNTSQYALT 490 E ++IC+ + + L Sbjct: 164 IEHDDICNKTLKITDFGLA 182 >2LKU-A nrPDB Length = 109 Score = 30.7 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%) Query: 14 RSFSQLGHIKPPKHIRNEPVKPFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERI 70 + F Q G + I PF ++++ + +LLR L ++ S L I+GE Sbjct: 28 KDFPQCGFSQTVVQILKSLNAPFESVNILENELLRQGLKEYSSWPTFPQLYIDGEFF 84 >1EAK-A nrPDB Length = 421 Score = 30.7 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 21/54 (38%), Gaps = 3/54 (5%) Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYD 142 +++ + V +A A + W ++ S I AD++ R++ Sbjct: 96 RIIGYTPDLDPETVDDAFA---RAFQVWSDVTPLRFSRIHDGEADIMINFGRWE 146 >1CK7-A nrPDB Length = 631 Score = 30.7 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 21/54 (38%), Gaps = 3/54 (5%) Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYD 142 +++ + V +A A + W ++ S I AD++ R++ Sbjct: 98 RIIGYTPDLDPETVDDAFA---RAFQVWSDVTPLRFSRIHDGEADIMINFGRWE 148 >1QIB-A nrPDB Length = 161 Score = 30.7 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 21/54 (38%), Gaps = 3/54 (5%) Query: 89 QVLANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYD 142 +++ + V +A A + W ++ S I AD++ R++ Sbjct: 13 RIIGYTPDLDPETVDDAFA---RAFQVWSDVTPLRFSRIHDGEADIMINFGRWE 63 >1CXV-A nrPDB Length = 164 Score = 30.4 bits (67), Expect = 2.4, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 18/41 (43%), Gaps = 3/41 (7%) Query: 95 TQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLI 135 + +V A + A K W ++ + + I+ AD++ Sbjct: 24 PDMSHSEVEKAF---RKAFKVWSDVTPLNFTRIYDGTADIM 61 >6IJO-6 nrPDB Length = 318 Score = 30.0 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Query: 251 EEAGLPKGVIN-FIPGDPVQVTDQVLADKDFGALHFTG 287 E G P GV FIPGD ++ + + + L F G Sbjct: 213 HEVGYPGGVFAPFIPGDLAELKVKEIKNGRLAMLAFVG 250 >1FBL-A nrPDB Length = 370 Score = 30.0 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 12/27 (44%), Gaps = 3/27 (11%) Query: 95 TQATEKDVMNAVKAAKDAKKDWYNLPF 121 + +DV A++ A + W N+ Sbjct: 24 PDLSREDVDRAIE---KAFQLWSNVSP 47 >5AYP-A nrPDB Length = 297 Score = 30.0 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 26/68 (38%), Gaps = 3/68 (4%) Query: 118 NLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITE--LSDFFRYYVK 175 +P R + + A + AA M G+GK + +E++ I +Y V Sbjct: 134 RIPPSVRLRLIERLAKAAGPEGMVAGQAADMEGEGKTLTLSELEYIHRHKTGKMLQYSV- 192 Query: 176 YASDLYAQ 183 +A L Sbjct: 193 HAGALIGG 200 >2DQ3-A nrPDB Length = 425 Score = 30.0 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 30/91 (32%), Gaps = 12/91 (13%) Query: 235 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQ------VLADKDFGALHFTGS 288 P+ L+N +L+E LP + + P + ++ F + Sbjct: 230 PTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGAYGKDIRGIIRQHQFDKV----- 284 Query: 289 TNVFKSLYGKIQSGVVEGKYRDYPRIIGETG 319 + K ++ +E +D ++ G Sbjct: 285 -ELVKIVHPDTSYDELEKLVKDAEEVLQLLG 314 >5HM5-A nrPDB Length = 854 Score = 30.0 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 48/149 (32%), Gaps = 19/149 (12%) Query: 40 DLKDWDLLRASLMKFKSSSLEVPLVING------ERIYDNNERAL--FPQTNPANHQQVL 91 DL + + + K + L I G ERI + + L NP +++ Sbjct: 602 DLLELGATPKAAAEIKGPEFKFLLNIEGVGPKLAERILEAVDYDLERLASLNP---EELA 658 Query: 92 ANVTQATEKDVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATML-- 149 V E+ V AA++ + +RS + + + K + Sbjct: 659 EKVEGLGEELAERVVYAARERVESRRKSGRQERSE--EEWKEWLERKVGEGRARRLIEYF 716 Query: 150 ----GQGKNVYQAEIDCITELSDFFRYYV 174 GK V AE+ + E+ V Sbjct: 717 GSAGEVGKLVENAEVSKLLEVPGIGDEAV 745 >2IPH-A nrPDB Length = 181 Score = 30.0 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 434 KSQGWFVGPTVIKAKRPDHPYMSTEFFG-PILTVYEYPDTEF 474 G++V PTV P + EFFG P+ ++ + EF Sbjct: 14 SGWGFWVSPTVFITTTHVIPTSAKEFFGEPLTSIAIHRAGEF 55 >3B97-A nrPDB Length = 433 Score = 30.0 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 31/78 (39%), Gaps = 6/78 (7%) Query: 252 EAGLPKGVINFIPGDPVQVTDQVLADK----DFGALHFTGSTNVFKSLYGKIQSGVVEGK 307 E LP N I G +++ + GA +F + + +Y +++ + E Sbjct: 141 EVILPVPAFNVING-GSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKY 199 Query: 308 YRDYPRIIGETGGKNFHL 325 +D + E GG ++ Sbjct: 200 GKDATNVGDE-GGFAPNI 216 >1WQS-A nrPDB Length = 173 Score = 29.2 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 434 KSQGWFVGPTVIKAKRPDHPYMSTEFFG-PILTVYEYPDTEFNE 476 G++V PTV P EFFG PI ++ + EF + Sbjct: 14 SGWGFWVSPTVFITTTHVIPTGVREFFGEPIESIAIHRAGEFTQ 57 >3SVK-A nrPDB Length = 407 Score = 29.2 bits (64), Expect = 5.7, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 17/53 (32%), Gaps = 1/53 (1%) Query: 66 NGERIYDNNERALFPQTNPANHQQVLANVTQATEKDVMN-AVKAAKDAKKDWY 117 G D ++A + + +DV A+++ + A W Sbjct: 135 GGAWATDPETNYRIGFVPQGIGADLIATLEGFSREDVDAYALRSQQKAAAAWS 187 >6DX7-A nrPDB Length = 397 Score = 28.8 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 38/104 (36%), Gaps = 14/104 (13%) Query: 19 LGHIKPPKHIRNE--PVKPFRNIDLKDWDLLRASLMKF--KSSSLEVPLVINGERIYDNN 74 +G PP P F + + + L+A + KS + + + E + N Sbjct: 28 IGTAVPPAEFLQSEYPEFFFNITNCGEKEALKAKFKRICDKSGIRKRHMFLTEEVLKANP 87 Query: 75 ERALF--PQTNPANHQQVLANVTQATEKDVMNAVKAAKDAKKDW 116 + P N H V+ V + A +AA+ A K+W Sbjct: 88 GICTYMEPSLN-VRHDIVVVQVPKL-------AAEAAQKAIKEW 123 >3A2Q-A nrPDB Length = 493 Score = 28.8 bits (63), Expect = 7.5, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 14/56 (25%) Query: 125 SAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASDL 180 + + +LI D + T K Q D RYY Sbjct: 321 AREIERNGELIGRPLTEDDVEWTSWEMVKRADQVTGRAFAACVDELRYYAGKVERW 376 >2MMA-A nrPDB Length = 109 Score = 28.4 bits (62), Expect = 8.3, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 19/36 (52%) Query: 35 PFRNIDLKDWDLLRASLMKFKSSSLEVPLVINGERI 70 PF ++++ + ++LR L ++ + L I GE Sbjct: 49 PFEDVNILENEMLRQGLKEYSNWPTFPQLYIGGEFF 84 >3CZP-A nrPDB Length = 500 Score = 28.0 bits (61), Expect = 10.0, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 49/131 (37%), Gaps = 19/131 (14%) Query: 43 DWDLLRASLMKFKSSSLEVPLVINGERIYDNNERALFPQTNPANHQQVLA--NVTQATEK 100 LL A + + V ++ING I + N +++ + + +++ Sbjct: 26 REALLEAQFELKQQARFPVIILING--IEGAGKGETVKLLNEWMDPRLIEVQSFLRPSDE 83 Query: 101 DVMNAVKAAKDAKKDWYNLPFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEI 160 ++ + + W LP R+ IF + ML A + G + +A++ Sbjct: 84 ELERPPQ-----WRFWRRLPPKGRTGIFF-------GNWYSQMLYARVEGH---IKEAKL 128 Query: 161 DCITELSDFFR 171 D + ++ F Sbjct: 129 DQAIDAAERFE 139 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.139 0.394 Lambda K H 0.267 0.0427 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,965,260 Number of Sequences: 36641 Number of extensions: 957854 Number of successful extensions: 4477 Number of sequences better than 10.0: 148 Number of HSP's better than 10.0 without gapping: 205 Number of HSP's successfully gapped in prelim test: 55 Number of HSP's that attempted gapping in prelim test: 2991 Number of HSP's gapped (non-prelim): 277 length of query: 575 length of database: 10,336,785 effective HSP length: 102 effective length of query: 473 effective length of database: 6,599,403 effective search space: 3121517619 effective search space used: 3121517619 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.4 bits)