BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07257 (368 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3CX5-B nrPDB 705 0.0 3L73-B nrPDB 85 4e-17 2BCC-B nrPDB 67 1e-11 6HAW-B nrPDB 62 3e-10 5XTH-AK nrPDB 62 3e-10 3HDI-A nrPDB 60 1e-09 1HR7-A nrPDB 59 5e-09 1HR8-B nrPDB 57 2e-08 5GUP-v nrPDB 54 1e-07 3L72-A nrPDB 46 2e-05 6HAW-A nrPDB 44 8e-05 1BCC-A nrPDB 43 2e-04 5XTH-AL nrPDB 43 2e-04 2QNE-A nrPDB 34 0.081 1BXN-A nrPDB 30 1.3 1PIX-A nrPDB 30 1.4 1GPU-A nrPDB 29 3.2 5WYK-3E nrPDB 29 3.2 5EUF-A nrPDB 28 6.7 6MRO-A nrPDB 28 8.6 >3CX5-B nrPDB Length = 352 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/352 (100%), Positives = 352/352 (100%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGG 76 LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGG Sbjct: 1 LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGG 60 Query: 77 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ 136 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ Sbjct: 61 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ 120 Query: 137 CPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEAD 196 CPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEAD Sbjct: 121 CPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEAD 180 Query: 197 LKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVL 256 LKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVL Sbjct: 181 LKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVL 240 Query: 257 ANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSP 316 ANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSP Sbjct: 241 ANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSP 300 Query: 317 AINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL 368 AINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL Sbjct: 301 AINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL 352 >3L73-B nrPDB Length = 441 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 96/396 (24%), Positives = 163/396 (41%), Gaps = 57/396 (14%) Query: 29 STLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREY 86 S + V + GSRY T G AHLL + T S+ ++ R E +GG+ RE Sbjct: 47 SRIGVFIKAGSRYETTANLGTAHLLRLASPLTTKGASSFRITRGIEAVGGSLSVYSTREK 106 Query: 87 ITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQL 146 +T L+D + + L +V F+P E+T+ + P + D AVA Q P + L Sbjct: 107 MTYCVECLRDHVDTVMEYLLNVTTAPEFRPWEVTD-LQPQLKVDKAVAFQSPQVGVLENL 165 Query: 147 YAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDES 204 +A ++ L NPL + +++ + + F +T + + G V +DLK+ ++ Sbjct: 166 HAAAYKTALANPLYCPDYRIGKITSEQLHHFVQNNFTSARMALVGIGVKHSDLKQVAEQF 225 Query: 205 LLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVLANYL---- 260 L AG S + + E+N + +V G V A + VL + L Sbjct: 226 LNIRSGAGTSSAKATYWGGEIREQNGHSLVHAAVVTEGAAVGSAEANAFSVLQHVLGAGP 285 Query: 261 -----TSALSELSGLISSAKLDKF---------TDGGLFTLFVRDQDSA---VVSSNIKK 303 +S S+L ++ A F +D GLF + Q + V+ + + + Sbjct: 286 LIKRGSSVTSKLYQGVAKATTQPFDASAFNVNYSDSGLFGFYTISQAAHAGEVIRAAMNQ 345 Query: 304 IVADLKKG---KDLSPAINYTK------------LKNAVQNESVSSPIELN--------- 339 + A + G +D++ A N K L N + +E++ S Sbjct: 346 LKAAAQGGVTEEDVTKAKNQLKATYLMSVETAQGLLNEIGSEALLSGTHTAPSVVAQKID 405 Query: 340 -------FDAVKDFKLGKFNYVAVGDVSNLPYLDEL 368 +A K F GK + A GD+ + P+LDEL Sbjct: 406 SVTSADVVNAAKKFVSGKKSMAASGDLGSTPFLDEL 441 >2BCC-B nrPDB Length = 422 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 76/289 (26%), Positives = 122/289 (42%), Gaps = 29/289 (10%) Query: 29 STLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREY 86 ST+ V + GSRY G +HLL + T S+ K+ R E +GG RE Sbjct: 28 STIGVFIKAGSRYENSSNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVESTREN 87 Query: 87 ITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQL 146 + L+DD+ + L +V F+P E+ + + P + D AVA Q P + L Sbjct: 88 MAYTVECLRDDVEILMEFLLNVTTAPEFRPWEVAD-LQPQLKIDKAVAFQNPQTHVIENL 146 Query: 147 YAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDES 204 +A +R L + L + +V+ ++ DF +T + + G V LK V E Sbjct: 147 HAAAYRNALADSLYCPDYRIGKVTSVELHDFVQNHFTSARMALVGLGVSHPVLKN-VAEQ 205 Query: 205 LLSTLPAGKSLVSKSEPKFFLG---EEN-----RVRFIGDSVAAIGIPVNKASLAQYEVL 256 LL+ G +S ++ K+ G E+N + +S A G N S+ Q+ + Sbjct: 206 LLNI--RGGLGLSGAKAKYRGGEIREQNGDSLVHAAIVAESAAIGGAEANAFSVLQHVLG 263 Query: 257 AN-YLTSALSELSGLIS------------SAKLDKFTDGGLFTLFVRDQ 292 AN ++ L+ S L SA ++D GLF + Q Sbjct: 264 ANPHVKRGLNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGFYTISQ 312 >6HAW-B nrPDB Length = 413 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 90/396 (22%), Positives = 152/396 (38%), Gaps = 62/396 (15%) Query: 29 STLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREY 86 S + + + GSRY + G +HLL + T S+ K+ R E +GG T RE Sbjct: 24 SRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTREN 83 Query: 87 ITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQL 146 + L+DD+ + L +V F+ E+ ++ P R D AVA Q P + L Sbjct: 84 MAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVA-ALQPQLRIDKAVALQNPQAHVIENL 142 Query: 147 YAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDES 204 +A +R L N L + +V+ ++ D+ +T + + G V LK+ V E Sbjct: 143 HAAAYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQ-VAEQ 201 Query: 205 LLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVLANYL---- 260 L+ K+ E + E+N + ++ A + A + VL + L Sbjct: 202 FLNIRGGAKAKYHGGEIR----EQNGDSLVHAALVAESAAIGSAEANAFSVLQHVLGAGP 257 Query: 261 -----TSALSELSGLIS---------SAKLDKFTDGGLFTLFVRDQDSA------VVSSN 300 ++A S L ++ SA ++D GLF + Q ++ + Sbjct: 258 HVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGFYTISQAASAGDVIKAAYNQ 317 Query: 301 IKKIVADLKKGKDLSPAINYTKLKNAVQNESVS-------------------SPIELNFD 341 +K I D+ A N K + ES S + D Sbjct: 318 VKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQID 377 Query: 342 AVKD---------FKLGKFNYVAVGDVSNLPYLDEL 368 AV D F G+ + A G++ + P++DEL Sbjct: 378 AVADADVINAAKKFVSGRKSMAASGNLGHTPFIDEL 413 >5XTH-AK nrPDB Length = 419 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 92/411 (22%), Positives = 161/411 (39%), Gaps = 63/411 (15%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYA--TKDGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L +++ + + +S + + + GSRY + G HLL + T S+ K+ R E + Sbjct: 13 LVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAV 72 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG T RE + L+ D+ + L +V F+ E+ + + P + D AVA Sbjct: 73 GGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVAD-LQPQLKIDKAVA 131 Query: 135 EQCPVKSAEDQLYAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENV 192 Q P + L+A +R L NPL + +V+ +++ F +T + + G V Sbjct: 132 FQNPQTHVIENLHAAAYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGV 191 Query: 193 VEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLG---EEN-----RVRFIGDSVAAIGIP 244 LK+ ++ L + G L S ++ + G E+N F+ +S A Sbjct: 192 SHPVLKQVAEQFL--NMRGGLGL-SGAKANYRGGEIREQNGDSLVHAAFVAESAVAGSAE 248 Query: 245 VNKASLAQYEVLA-------NYLTSALSELSGLISSAKLD------KFTDGGLFTLFVRD 291 N S+ Q+ + A + TS L + + D ++D GLF ++ Sbjct: 249 ANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTIS 308 Query: 292 QDSA------VVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIE-------- 337 Q +A + +K I D+ A N K + ES +E Sbjct: 309 QATAAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALV 368 Query: 338 -----------------LNFD---AVKDFKLGKFNYVAVGDVSNLPYLDEL 368 N D A K F G+ + A G++ + P++DEL Sbjct: 369 AGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTPFVDEL 419 >3HDI-A nrPDB Length = 421 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 66/291 (22%), Positives = 126/291 (43%), Gaps = 26/291 (8%) Query: 19 VSARDAPTKISTLAVKVHGGSRY--ATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGG 76 ++ + + + ++ + V GSRY A ++G++H L F+ TNTRSA ++ + +GG Sbjct: 14 ITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNTRSAQEIAEFFDSIGG 73 Query: 77 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ 136 + +EY A L D ++ L+D+ + + F+ EL E + + + Sbjct: 74 QVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEEL-EKERKVVFEEIKMVDD 132 Query: 137 CPVKSAEDQLYAITFRK-GLGNPLL--YDGVERVSLQDIKDFADKVYTKENLEVSGENVV 193 P D L + T+ K LG P+L + + + ++ + D+ YT + + +S V Sbjct: 133 TPDDIVHDLLSSATYGKHSLGYPILGTVETLNSFNEGMLRHYMDRFYTGDYVVISVAGNV 192 Query: 194 EADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAI------GIPVNK 247 +L + E+ P + + E FL NR+ ++ A G+P+ Sbjct: 193 HDELIDKIKETFSQVKPTTYNY--QGEKPMFL--PNRIVRKKETEQAHLCLGYPGLPIGD 248 Query: 248 ASLAQYEVLANYLTSALS--------ELSGLISS--AKLDKFTDGGLFTLF 288 + +L N L ++S E GL S + F D G+ T++ Sbjct: 249 KDVYALVLLNNVLGGSMSSRLFQDIREKRGLCYSVFSYHSSFRDSGMLTIY 299 >1HR7-A nrPDB Length = 475 Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 6/173 (3%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V+ + P S L + + GSR+ ++ G H+L+R F++T + ELL Sbjct: 15 LKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELL 74 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG ++ T RE + +A+ D+ + +++ + EL E L +A Y+ Sbjct: 75 GGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL-SAEYEIDEV 133 Query: 135 EQCPVKSAEDQLYAITFR-KGLGNPLLYDG--VERVSLQDIKDFADKVYTKEN 184 P + L+ + + LG+PL+ + +S + D+ +K YT EN Sbjct: 134 WMKPELVLPELLHTAAYSGETLGSPLICPRGLIPSISKYYLLDYRNKFYTPEN 186 >1HR8-B nrPDB Length = 443 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 83/363 (22%), Positives = 145/363 (39%), Gaps = 77/363 (21%) Query: 17 LTVSARDAP-TKISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESEL 73 LT++ P T +T+ + V GSR +G AH L F+ T R + E E Sbjct: 16 LTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKGTQNRPQQGIELEIEN 75 Query: 74 LGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAV 133 +G + RE A L++D+P V+ L+D+L K+ L S + R D + Sbjct: 76 IGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSV-----LDNSAIERER-DVII 129 Query: 134 AEQCPVKSAEDQ-----LYAITFR-KGLGNPLL--YDGVERVSLQDIKDFADKVYTKENL 185 E V D+ L+ IT++ + LG +L ++ ++ D+KD+ K Y + + Sbjct: 130 RESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRM 189 Query: 186 EVSGENVVEADL----------------------------------KRFVDESLLSTLPA 211 ++G V+ + +RF+ E+ L T Sbjct: 190 VLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHI 249 Query: 212 GKSL--VSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKAS-----LAQYEVLAN-YLTSA 263 +L VS S P +F+ + +G+ AIG N S +Q LAN Y++ + Sbjct: 250 AIALEGVSWSAPDYFVALATQA-IVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFS 308 Query: 264 LSELSGLISSAKLDKFTDGGLFTLFV----RDQDSAVVSSNIKKIVADLKKGKDLSPAIN 319 S + D GL+ +++ + + ++ + I K +K GK +N Sbjct: 309 TS-------------YADSGLWGMYIVTDSNEHNVRLIVNEILKEWKRIKSGKISDAEVN 355 Query: 320 YTK 322 K Sbjct: 356 RAK 358 >5GUP-v nrPDB Length = 453 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 91/401 (22%), Positives = 157/401 (39%), Gaps = 67/401 (16%) Query: 29 STLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREY 86 S + + + GSRY + G +HLL + T S+ K+ R E +GG T RE Sbjct: 59 SRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRES 118 Query: 87 ITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQL 146 + L+DD+ + L +V F+ E+ ++ R D AVA Q P + L Sbjct: 119 MAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVA-ALQSQLRIDKAVAFQNPQAQVLENL 177 Query: 147 YAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDES 204 +A +R L N L + +V+ + + +T + + G V LK+ + Sbjct: 178 HAAAYRNALANSLYCPDYRIGKVTPDQLHYYVQNHFTSARMALIGLGVSHPVLKQVAERF 237 Query: 205 LLSTLPAGKSLVSKSEPKFFLGE---ENRVRFIGDSVAAIGIPVNKASLAQYEVLANYL- 260 L + G L S ++ K+ GE +N + ++ A A + VL + L Sbjct: 238 L--NMRGGLGL-SGAKAKYRGGEIRDQNGDSLVHAALVAESAATGSAEANAFSVLQHVLG 294 Query: 261 --------TSALSELSGLIS---------SAKLDKFTDGGLFTLFV-------------- 289 ++A S L ++ SA ++D GLF ++ Sbjct: 295 AGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGIYTISQAASAGDVIKSA 354 Query: 290 RDQDSAVVSSN-----IKKIVADLKKGKDLS----------------PAINYTKLKNAVQ 328 DQ A+ N ++ LK G +S A +Y + +Q Sbjct: 355 YDQVKAIAQGNLSNTDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGSYMQPSTVLQ 414 Query: 329 N-ESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL 368 +SV+ +N A K F G+ + A G++ + P++DEL Sbjct: 415 QIDSVADADVIN--AAKKFVSGRKSMAASGNLGHTPFVDEL 453 >3L72-A nrPDB Length = 446 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 2/105 (1%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V++ ++ T+ V + GSRY + +G + + F+ T R +E E + Sbjct: 23 LRVASEESSQPTCTVGVWIGAGSRYENEKNNGAGYFVEHLAFKGTKKRPCAAFEKEVESM 82 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHEL 119 G F RE L D+P V LADV+ A + ++ Sbjct: 83 GAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNCALEESQI 127 >6HAW-A nrPDB Length = 438 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 2/101 (1%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V++ + T+ V + GSRY ++ +G + + F+ T R L +E E + Sbjct: 22 LRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRPGNALEKEVESM 81 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFK 115 G + RE+ L DLP V LAD++ + + Sbjct: 82 GAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLE 122 >1BCC-A nrPDB Length = 446 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 2/99 (2%) Query: 19 VSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELLGG 76 V++ + T+ V + GSRY ++ +G + L F+ T R L +E E +G Sbjct: 25 VASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFLEHLAFKGTKNRPQNALEKEVESMGA 84 Query: 77 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFK 115 + RE+ L D+P V LAD++ + + Sbjct: 85 HLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNCSLE 123 >5XTH-AL nrPDB Length = 446 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 2/101 (1%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V++ + T+ V + GSR+ T+ +G + L F+ T R L +E E + Sbjct: 23 LRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPGSALEKEVESM 82 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFK 115 G + RE+ L DLP V L D++ + + Sbjct: 83 GAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLE 123 >2QNE-A nrPDB Length = 495 Score = 34.3 bits (77), Expect = 0.081, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 111 KTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQLYAITFRKGLGNPLLY--DGVER-V 167 K + E ES L +A ++ + + P + I F G G P +Y DG R Sbjct: 69 KRVYLTREFVESKLKSAPAEFTLHARNPENNVVIGGDNIVFMPGYGAPFIYELDGSRRKT 128 Query: 168 SLQDIKDFADKVYTKENLEVSGENVVE 194 +LQD ++FA +N+ +SG + E Sbjct: 129 TLQDYENFAKLAGASKNMHLSGGTMAE 155 >1BXN-A nrPDB Length = 485 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 41/144 (28%), Positives = 57/144 (39%), Gaps = 17/144 (11%) Query: 138 PVKSA--EDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEA 195 P+K+A ED + + + K P VER L TK L +SG N Sbjct: 131 PIKAARLEDMRFPVAYVKTFAGPSTGIIVERERLDKFGRPLLGATTKPKLGLSGRN---- 186 Query: 196 DLKRFVDESLLSTLPAGKSLVS-KSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYE 254 R V E L L K + S+P F+ +R F+ D+V NKAS A E Sbjct: 187 -YGRVVYEGLKGGLDFMKDDENINSQP--FMHWRDRFLFVMDAV-------NKASAATGE 236 Query: 255 VLANYLTSALSELSGLISSAKLDK 278 V +YL + + A+ K Sbjct: 237 VKGSYLNVTAGTMEEMYRRAEFAK 260 >1PIX-A nrPDB Length = 587 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 245 VNKASLAQYEVLANYLTSALSELSGLISSAKLDKFTDGGLFT-LFVRDQDSAVVSSNIKK 303 + + + Q+E+ T+A + G + F+ G T + V + ++A + ++ Sbjct: 440 IQTSHIPQFEITLRKGTAAAHYVLGGPQGNDTNAFSIGTAATEIAVMNGETAATAMYSRR 499 Query: 304 IVADLKKGKDLSPAINYTKLKNAVQ 328 + D K GKDL P I+ K+ N +Q Sbjct: 500 LAKDRKAGKDLQPTID--KMNNLIQ 522 >1GPU-A nrPDB Length = 680 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 21/97 (21%), Positives = 40/97 (41%), Gaps = 3/97 (3%) Query: 167 VSLQDIKDF---ADKVYTKENLEVSGENVVEADLKRFVDESLLSTLPAGKSLVSKSEPKF 223 +S++D+K F + E+ G V L + + ++ + + ++P F Sbjct: 85 LSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGF 144 Query: 224 FLGEENRVRFIGDSVAAIGIPVNKASLAQYEVLANYL 260 L + F+GD GI +SLA + L N + Sbjct: 145 TLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLI 181 >5WYK-3E nrPDB Length = 511 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 30/49 (61%), Gaps = 6/49 (12%) Query: 297 VSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELNFDAVKD 345 VSS ++K++ ++KK K + ++ TKL NA+ + + LNF+ V D Sbjct: 68 VSSQLEKLLEEIKKDKKSTLIVSETKLANAI------NKLGLNFNVVSD 110 >5EUF-A nrPDB Length = 419 Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust. Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 30/206 (14%) Query: 38 GSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKST----LDREYITLKA 91 GSR K G+AH+L NF++T A + + + GG ++ + R +I Sbjct: 40 GSRNEVMGKSGIAHMLEHLNFKSTKNLKAGEFDKIVKRFGGVSNASTSFDITRYFIKTSE 99 Query: 92 TFLKDDLPYYVNALADV-LYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQLY--A 148 L L + + + L + F P + V R+ + P+ + + A Sbjct: 100 ANLDKSLELFAETMGSLNLKEDEFLPER--QVVAEERRWR---TDNSPIGMLYFRFFNTA 154 Query: 149 ITFRKGLGNPL-LYDGVERVSLQDIKDFADKVYTKENL------EVSGENVVEADLKRFV 201 + P+ D ++ +L+DIK F Y +N +V+ + V E K F Sbjct: 155 YVYHPYHWTPIGFMDDIQNWTLKDIKKFHSLYYQPKNAIVLVVGDVNSQKVFELTKKHF- 213 Query: 202 DESLLSTLPAGKSLVSKSEPKFFLGE 227 ESL K+L K+ P ++ E Sbjct: 214 -ESL-------KNLDEKAIPTPYMKE 231 >6MRO-A nrPDB Length = 194 Score = 27.7 bits (60), Expect = 8.6, Method: Compositional matrix adjust. Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 4/84 (4%) Query: 228 ENRVRFIGDSVAAIGIPVNKASLAQYEVLANYLTSALSELSGLISSAKLDKFTDGGLFTL 287 +N G +A I KA + V N++ + E+ L + + D D GLF + Sbjct: 52 KNGCDVTGIDLAKRAISDAKAKAIERHVKVNFIVGNVLEMDQLFTEDEFDIVIDSGLFHV 111 Query: 288 FVRDQDSAVVSSNIKKIVADLKKG 311 + D++ + + ++ K+ LK+G Sbjct: 112 -ITDEERLLFTRHVHKV---LKEG 131 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3CX5-B nrPDB 421 e-118 5XTH-AK nrPDB 372 e-103 6HAW-B nrPDB 371 e-103 2BCC-B nrPDB 361 e-100 5GUP-v nrPDB 361 e-100 3L73-B nrPDB 352 1e-97 3HDI-A nrPDB 279 2e-75 1HR8-B nrPDB 267 4e-72 1HR7-A nrPDB 225 2e-59 1BCC-A nrPDB 196 8e-51 6HAW-A nrPDB 196 1e-50 3L72-A nrPDB 195 4e-50 5XTH-AL nrPDB 188 2e-48 Sequences not found previously or not previously below threshold: 3EOQ-A nrPDB 92 3e-19 4NNZ-A nrPDB 87 1e-17 6GIQ-A nrPDB 79 3e-15 5EUF-A nrPDB 79 4e-15 5CIO-A nrPDB 58 5e-09 1Q2L-A nrPDB 57 1e-08 3GO9-A nrPDB 39 0.004 3WKF-A nrPDB 34 0.15 1D0N-A nrPDB 32 0.48 4RJW-A nrPDB 31 0.82 4R86-A nrPDB 30 1.9 3QQ2-A nrPDB 29 2.8 1NPH-A nrPDB 29 4.2 4WAI-A nrPDB 29 4.2 1NL3-A nrPDB 29 4.7 >3CX5-B nrPDB Length = 352 Score = 421 bits (1082), Expect = e-118, Method: Composition-based stats. Identities = 352/352 (100%), Positives = 352/352 (100%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGG 76 LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGG Sbjct: 1 LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGG 60 Query: 77 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ 136 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ Sbjct: 61 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ 120 Query: 137 CPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEAD 196 CPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEAD Sbjct: 121 CPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEAD 180 Query: 197 LKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVL 256 LKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVL Sbjct: 181 LKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVL 240 Query: 257 ANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSP 316 ANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSP Sbjct: 241 ANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSP 300 Query: 317 AINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL 368 AINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL Sbjct: 301 AINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL 352 >5XTH-AK nrPDB Length = 419 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 86/408 (21%), Positives = 154/408 (37%), Gaps = 57/408 (13%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYA--TKDGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L +++ + + +S + + + GSRY + G HLL + T S+ K+ R E + Sbjct: 13 LVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAV 72 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG T RE + L+ D+ + L +V F+ E+ + + P + D AVA Sbjct: 73 GGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVAD-LQPQLKIDKAVA 131 Query: 135 EQCPVKSAEDQLYAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENV 192 Q P + L+A +R L NPL + +V+ +++ F +T + + G V Sbjct: 132 FQNPQTHVIENLHAAAYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGV 191 Query: 193 VEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQ 252 LK+ ++ L G S + + E+N + + A A Sbjct: 192 SHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAAFVAESAVAGSAEANA 251 Query: 253 YEVLANYL---------TSALSELSGLIS---------SAKLDKFTDGGLFTLFVRDQDS 294 + VL + L ++ S L ++ SA ++D GLF ++ Q + Sbjct: 252 FSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQAT 311 Query: 295 A------VVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELN--------- 339 A + +K I D+ A N K + ES +E Sbjct: 312 AAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGS 371 Query: 340 -------------------FDAVKDFKLGKFNYVAVGDVSNLPYLDEL 368 +A K F G+ + A G++ + P++DEL Sbjct: 372 YMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTPFVDEL 419 >6HAW-B nrPDB Length = 413 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 90/408 (22%), Positives = 156/408 (38%), Gaps = 62/408 (15%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELL 74 L +++ + S + + + GSRY + G +HLL + T S+ K+ R E + Sbjct: 12 LVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSFKITRGIEAV 71 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG T RE + L+DD+ + L +V F+ E+ ++ P R D AVA Sbjct: 72 GGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVA-ALQPQLRIDKAVA 130 Query: 135 EQCPVKSAEDQLYAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENV 192 Q P + L+A +R L N L + +V+ ++ D+ +T + + G V Sbjct: 131 LQNPQAHVIENLHAAAYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGV 190 Query: 193 VEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQ 252 LK+ V E L+ K+ E + E+N + ++ A + A Sbjct: 191 SHPVLKQ-VAEQFLNIRGGAKAKYHGGE----IREQNGDSLVHAALVAESAAIGSAEANA 245 Query: 253 YEVLANYL---------TSALSELSGLIS---------SAKLDKFTDGGLFTLFVRDQDS 294 + VL + L ++A S L ++ SA ++D GLF + Q + Sbjct: 246 FSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGFYTISQAA 305 Query: 295 A------VVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVS--------------- 333 + + +K I D+ A N K + ES Sbjct: 306 SAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALAAGS 365 Query: 334 ----SPIELNFD---------AVKDFKLGKFNYVAVGDVSNLPYLDEL 368 S + D A K F G+ + A G++ + P++DEL Sbjct: 366 YTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAASGNLGHTPFIDEL 413 >2BCC-B nrPDB Length = 422 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 88/408 (21%), Positives = 153/408 (37%), Gaps = 57/408 (13%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELL 74 L +++ + + ST+ V + GSRY G +HLL + T S+ K+ R E + Sbjct: 16 LVIASLENYSPGSTIGVFIKAGSRYENSSNLGTSHLLRLASSLTTKGASSFKITRGIEAV 75 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG RE + L+DD+ + L +V F+P E+ + + P + D AVA Sbjct: 76 GGKLSVESTRENMAYTVECLRDDVEILMEFLLNVTTAPEFRPWEVAD-LQPQLKIDKAVA 134 Query: 135 EQCPVKSAEDQLYAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENV 192 Q P + L+A +R L + L + +V+ ++ DF +T + + G V Sbjct: 135 FQNPQTHVIENLHAAAYRNALADSLYCPDYRIGKVTSVELHDFVQNHFTSARMALVGLGV 194 Query: 193 VEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQ 252 LK ++ L G S + E+N + ++ A + A Sbjct: 195 SHPVLKNVAEQLLNIRGGLGLSGAKAKYRGGEIREQNGDSLVHAAIVAESAAIGGAEANA 254 Query: 253 YEVLANYLT---------SALSELSGLIS---------SAKLDKFTDGGLFTLFVRDQDS 294 + VL + L +A S L ++ SA ++D GLF + Q + Sbjct: 255 FSVLQHVLGANPHVKRGLNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGFYTISQAA 314 Query: 295 ------AVVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVS--------------- 333 + +K I +++ A N K K + ES Sbjct: 315 YAGQVIKAAYNQVKTIAQGNVSNENVQAAKNKLKAKYLMSVESSEGFLEEVGSQALAAGS 374 Query: 334 ----SPIELNFD---------AVKDFKLGKFNYVAVGDVSNLPYLDEL 368 S + D A K F + + A G++ + P++DEL Sbjct: 375 YNPPSTVLQQIDAVADADVIKAAKKFVSRQKSMAASGNLGHTPFVDEL 422 >5GUP-v nrPDB Length = 453 Score = 361 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 85/408 (20%), Positives = 149/408 (36%), Gaps = 57/408 (13%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELL 74 L +++ + S + + + GSRY + G +HLL + T S+ K+ R E + Sbjct: 47 LVIASLENYAPASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAV 106 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG T RE + L+DD+ + L +V F+ E+ ++ R D AVA Sbjct: 107 GGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVA-ALQSQLRIDKAVA 165 Query: 135 EQCPVKSAEDQLYAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENV 192 Q P + L+A +R L N L + +V+ + + +T + + G V Sbjct: 166 FQNPQAQVLENLHAAAYRNALANSLYCPDYRIGKVTPDQLHYYVQNHFTSARMALIGLGV 225 Query: 193 VEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQ 252 LK+ + L G S + ++N + ++ A A Sbjct: 226 SHPVLKQVAERFLNMRGGLGLSGAKAKYRGGEIRDQNGDSLVHAALVAESAATGSAEANA 285 Query: 253 YEVLANYL---------TSALSELSGLIS---------SAKLDKFTDGGLFTLFVRDQDS 294 + VL + L ++A S L ++ SA ++D GLF ++ Q + Sbjct: 286 FSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGIYTISQAA 345 Query: 295 AV------VSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVS--------------- 333 + +K I D+ A N K + ES Sbjct: 346 SAGDVIKSAYDQVKAIAQGNLSNTDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGS 405 Query: 334 ----SPIELNFD---------AVKDFKLGKFNYVAVGDVSNLPYLDEL 368 S + D A K F G+ + A G++ + P++DEL Sbjct: 406 YMQPSTVLQQIDSVADADVINAAKKFVSGRKSMAASGNLGHTPFVDEL 453 >3L73-B nrPDB Length = 441 Score = 352 bits (903), Expect = 1e-97, Method: Composition-based stats. Identities = 95/408 (23%), Positives = 167/408 (40%), Gaps = 57/408 (13%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L +++ + + S + V + GSRY T G AHLL + T S+ ++ R E + Sbjct: 35 LIIASLENFSPASRIGVFIKAGSRYETTANLGTAHLLRLASPLTTKGASSFRITRGIEAV 94 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG+ RE +T L+D + + L +V F+P E+T+ + P + D AVA Sbjct: 95 GGSLSVYSTREKMTYCVECLRDHVDTVMEYLLNVTTAPEFRPWEVTD-LQPQLKVDKAVA 153 Query: 135 EQCPVKSAEDQLYAITFRKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGENV 192 Q P + L+A ++ L NPL + +++ + + F +T + + G V Sbjct: 154 FQSPQVGVLENLHAAAYKTALANPLYCPDYRIGKITSEQLHHFVQNNFTSARMALVGIGV 213 Query: 193 VEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQ 252 +DLK+ ++ L AG S + + E+N + +V G V A Sbjct: 214 KHSDLKQVAEQFLNIRSGAGTSSAKATYWGGEIREQNGHSLVHAAVVTEGAAVGSAEANA 273 Query: 253 YEVLANYL---------TSALSELSGLI---------SSAKLDKFTDGGLFTLFVRDQDS 294 + VL + L +S S+L + +SA ++D GLF + Q + Sbjct: 274 FSVLQHVLGAGPLIKRGSSVTSKLYQGVAKATTQPFDASAFNVNYSDSGLFGFYTISQAA 333 Query: 295 A---VVSSNIKKIVADLKKG---KDLSPAINYTKLKNAVQN------------ESVSSPI 336 V+ + + ++ A + G +D++ A N K + E++ S Sbjct: 334 HAGEVIRAAMNQLKAAAQGGVTEEDVTKAKNQLKATYLMSVETAQGLLNEIGSEALLSGT 393 Query: 337 ELN----------------FDAVKDFKLGKFNYVAVGDVSNLPYLDEL 368 +A K F GK + A GD+ + P+LDEL Sbjct: 394 HTAPSVVAQKIDSVTSADVVNAAKKFVSGKKSMAASGDLGSTPFLDEL 441 >3HDI-A nrPDB Length = 421 Score = 279 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 73/348 (20%), Positives = 140/348 (40%), Gaps = 32/348 (9%) Query: 19 VSARDAPTKISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESELLGG 76 ++ + + + ++ + V GSRY + ++G++H L F+ TNTRSA ++ + +GG Sbjct: 14 ITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNTRSAQEIAEFFDSIGG 73 Query: 77 TFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQ 136 + +EY A L D ++ L+D+ + + F+ EL E + + + Sbjct: 74 QVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEEL-EKERKVVFEEIKMVDD 132 Query: 137 CPVKSAEDQLYAITFRK-GLGNPLL--YDGVERVSLQDIKDFADKVYTKENLEVSGENVV 193 P D L + T+ K LG P+L + + + ++ + D+ YT + + +S V Sbjct: 133 TPDDIVHDLLSSATYGKHSLGYPILGTVETLNSFNEGMLRHYMDRFYTGDYVVISVAGNV 192 Query: 194 EADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAI------GIPVNK 247 +L + E+ P + + E FL NR+ ++ A G+P+ Sbjct: 193 HDELIDKIKETFSQVKPTTYNY--QGEKPMFL--PNRIVRKKETEQAHLCLGYPGLPIGD 248 Query: 248 ASLAQYEVLANYLTSALS--------ELSGLISS--AKLDKFTDGGLFTLFV------RD 291 + +L N L ++S E GL S + F D G+ T++ D Sbjct: 249 KDVYALVLLNNVLGGSMSSRLFQDIREKRGLCYSVFSYHSSFRDSGMLTIYAGTGHDQLD 308 Query: 292 QDSAVVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELN 339 + + K+L K + ES +S + N Sbjct: 309 DLVYSIQETTSALAEKGLTEKELENGKEQLKGSLMLSLESTNSRMSRN 356 >1HR8-B nrPDB Length = 443 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 83/364 (22%), Positives = 145/364 (39%), Gaps = 77/364 (21%) Query: 17 LTVSARDAP-TKISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESEL 73 LT++ P T +T+ + V GSR +G AH L F+ T R + E E Sbjct: 16 LTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKGTQNRPQQGIELEIEN 75 Query: 74 LGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAV 133 +G + RE A L++D+P V+ L+D+L K+ L S + R D + Sbjct: 76 IGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSV-----LDNSAIERER-DVII 129 Query: 134 AEQCPVKSAEDQ-----LYAITFR-KGLGNPLL--YDGVERVSLQDIKDFADKVYTKENL 185 E V D+ L+ IT++ + LG +L ++ ++ D+KD+ K Y + + Sbjct: 130 RESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSITRTDLKDYITKNYKGDRM 189 Query: 186 EVSGENVVEADL----------------------------------KRFVDESLLSTLPA 211 ++G V+ + +RF+ E+ L T Sbjct: 190 VLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKENTLPTTHI 249 Query: 212 GKSL--VSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKAS-----LAQYEVLAN-YLTSA 263 +L VS S P +F+ + +G+ AIG N S +Q LAN Y++ + Sbjct: 250 AIALEGVSWSAPDYFVALATQA-IVGNWDRAIGTGTNSPSPLAVAASQNGSLANSYMSFS 308 Query: 264 LSELSGLISSAKLDKFTDGGLFTLFV----RDQDSAVVSSNIKKIVADLKKGKDLSPAIN 319 S + D GL+ +++ + + ++ + I K +K GK +N Sbjct: 309 TS-------------YADSGLWGMYIVTDSNEHNVRLIVNEILKEWKRIKSGKISDAEVN 355 Query: 320 YTKL 323 K Sbjct: 356 RAKA 359 >1HR7-A nrPDB Length = 475 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 68/367 (18%), Positives = 128/367 (34%), Gaps = 50/367 (13%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKD--GVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V+ + P S L + + GSR+ ++ G H+L+R F++T + ELL Sbjct: 15 LKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELL 74 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 GG ++ T RE + +A+ D+ + +++ + EL E L +A Y+ Sbjct: 75 GGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKL-SAEYEIDEV 133 Query: 135 EQCPVKSAEDQLYAITF-RKGLGNPLLYDG--VERVSLQDIKDFADKVYTKENLEVSGEN 191 P + L+ + + LG+PL+ + +S + D+ +K YT EN + Sbjct: 134 WMKPELVLPELLHTAAYSGETLGSPLICPRGLIPSISKYYLLDYRNKFYTPENTVAAFVG 193 Query: 192 VVEADLKRFVD------ESLLSTLPAGKSLVSKSE-----PKFFLGEENRVRFIGDSVAA 240 V +S + + + E F + Sbjct: 194 VPHEKALELTGKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLP---ELFHIQIGF 250 Query: 241 IGIPVNKASLAQYEVLANYL------------TSALSELSGLISS---------AKLDKF 279 G+P++ + L L S L + + A + Sbjct: 251 EGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFNHSY 310 Query: 280 TDGGLFTLFV--RDQDSAVVSSNIKKIVADLKKGKD-------LSPAINYTKLKNAVQNE 330 +D G+F + + Q + I + + + KD +S A N K + E Sbjct: 311 SDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLMNLE 370 Query: 331 SVSSPIE 337 S +E Sbjct: 371 SKLVELE 377 >1BCC-A nrPDB Length = 446 Score = 196 bits (499), Expect = 8e-51, Method: Composition-based stats. Identities = 54/302 (17%), Positives = 111/302 (36%), Gaps = 31/302 (10%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELL 74 + V++ + T+ V + GSRY ++ +G + L F+ T R L +E E + Sbjct: 23 VRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFLEHLAFKGTKNRPQNALEKEVESM 82 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 G + RE+ L D+P V LAD++ + + ++ E + Sbjct: 83 GAHLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNCSLEDSQI-EKERDVIVRELQEN 141 Query: 135 EQCPVKSAEDQLYAITF-RKGLGNPLLYD--GVERVSLQDIKDFADKVYTKENLEVSGEN 191 + + + L+A F GL + + ++S D+ ++ YT + ++ Sbjct: 142 DTSMREVVFNYLHATAFQGTGLAQSVEGPSENIRKLSRADLTEYLSTHYTAPRMVLAAAG 201 Query: 192 VVEADLKRFVDESLLSTLPAGK---SLVSKSEPKFFLGE----ENRVRFIGDSVAAIGIP 244 VE + + +P ++ + S+ +F + E+ + ++A G Sbjct: 202 GVEHQQLLELAQKHFGGVPFTYDDDAVPTLSKCRFTGSQIRHREDGLPLAHVAIAVEGPG 261 Query: 245 VNKASLAQYEVLANYL-------TSALSELSGLISSAKLDK-----------FTDGGLFT 286 L +V + L S L S A +K +++ GLF Sbjct: 262 WAHPDLVALQVANAIIGHYDRTYGGGLHSSSPLASIAVTNKLCQSFQTFSICYSETGLFG 321 Query: 287 LF 288 + Sbjct: 322 FY 323 >6HAW-A nrPDB Length = 438 Score = 196 bits (499), Expect = 1e-50, Method: Composition-based stats. Identities = 45/294 (15%), Positives = 95/294 (32%), Gaps = 25/294 (8%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V++ + T+ V + GSRY ++ +G + + F+ T R L +E E + Sbjct: 22 LRVASEQSSQPTCTVGVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRPGNALEKEVESM 81 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 G + RE+ L DLP V LAD++ + + ++ E + Sbjct: 82 GAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQI-EKERDVILQELQEN 140 Query: 135 EQCPVKSAEDQLYAITF-RKGLGNPLLYD--GVERVSLQDIKDFADKVYTKENLEVSGE- 190 + + L+A F L + V ++S D+ ++ + Y + ++ Sbjct: 141 DTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAAG 200 Query: 191 NVVEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASL 250 + L + + E+ + ++A G Sbjct: 201 GLEHRQLLDLAQKHFSGLSGVPTLSPCRFTGSQICHREDGLPLAHVAIAVEGPGWAHPDN 260 Query: 251 AQYEVLANYLT----------------SALSELSGLISS--AKLDKFTDGGLFT 286 +V + ++++ + L S + D GL Sbjct: 261 VALQVANAIIGHYDCTYGGGAHLSSPLASIAATNKLCQSFQTFNICYADTGLLG 314 >3L72-A nrPDB Length = 446 Score = 195 bits (494), Expect = 4e-50, Method: Composition-based stats. Identities = 59/357 (16%), Positives = 112/357 (31%), Gaps = 36/357 (10%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V++ ++ T+ V + GSRY + +G + + F+ T R +E E + Sbjct: 23 LRVASEESSQPTCTVGVWIGAGSRYENEKNNGAGYFVEHLAFKGTKKRPCAAFEKEVESM 82 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 G F RE L D+P V LADV+ A + ++ E + Sbjct: 83 GAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNCALEESQI-EKERGVILQELKEM 141 Query: 135 EQCPVKSAEDQLYAITF-RKGLGNPL--LYDGVERVSLQDIKDFADKVYTKENLEVSGE- 190 + D L+A F L + + ++ ++ D+ + D + + ++ Sbjct: 142 DNDMTNVTFDYLHATAFQGTALARTVEGTTENIKHLTRADLASYIDTHFKAPRMVLAAAG 201 Query: 191 NVVEADLKRFVDESLLSTLPAGKSLVSKSEPK-FFLGEENRVR-----FIGDSVAAIGIP 244 + +L + K P+ F G E R R ++A G Sbjct: 202 GISHKELVDAARQHFSGVSFTYKEDAVPILPRCRFTGSEIRARDDALPVAHVALAVEGPG 261 Query: 245 VNKASLAQYEVLANYLTS----------------ALSELSGLISS--AKLDKFTDGGLFT 286 V + AL+ L S ++D GLF Sbjct: 262 WADPDNVVLHVANAIIGRYDRTFGGGKHLSSRLAALAVEHKLCHSFQTFNTSYSDTGLFG 321 Query: 287 LFVRDQDSAV--VSSNIKKIVADLKKGK---DLSPAINYTKLKNAVQNESVSSPIEL 338 ++ + + L ++ A N+ + Q + + E Sbjct: 322 FHFVADPLSIDDMMFCAQGEWMRLCTSTTESEVKRAKNHLRSAMVAQLDGTTPVCET 378 >5XTH-AL nrPDB Length = 446 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 53/300 (17%), Positives = 99/300 (33%), Gaps = 31/300 (10%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELL 74 L V++ + T+ V + GSR+ T+ +G + L F+ T R L +E E + Sbjct: 23 LRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPGSALEKEVESM 82 Query: 75 GGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVA 134 G + RE+ L DLP V L D++ + + ++ E + Sbjct: 83 GAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQI-EKERDVILREMQEN 141 Query: 135 EQCPVKSAEDQLYAITF-RKGLGNPLLYD--GVERVSLQDIKDFADKVYTKENLEVSGEN 191 + + L+A F L + V ++S D+ ++ Y + ++ Sbjct: 142 DASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTHYKAPRMVLAAAG 201 Query: 192 VVEADLKRFVDESLLSTLPAGKS--LVSKSEPKFFLGEENRVR-----FIGDSVAAIGIP 244 VE + + L +P + V P F G E R R F ++A G Sbjct: 202 GVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSEIRHRDDALPFAHVAIAVEGPG 261 Query: 245 VNKASLAQYEVLANYL------------------TSALSELSGLISSAKLDKFTDGGLFT 286 +V + + A++ + + GL Sbjct: 262 WASPDNVALQVANAIIGHYDCTYGGGVHLSSPLASGAVANKLCQSFQTFSICYAETGLLG 321 >3EOQ-A nrPDB Length = 406 Score = 92.2 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 43/213 (20%), Positives = 79/213 (37%), Gaps = 9/213 (4%) Query: 9 FAQGSVRR-LTVSARDAPT-KISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSA 64 F + +R L V A P + L V G+R T + GV+H L F+ A Sbjct: 2 FREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDA 61 Query: 65 LKLVRESELLGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVL 124 L + R + +G + + E L + + A +L A + + L Sbjct: 62 LAVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLLR-PALREEDFQTEKL 120 Query: 125 PAARYDYAVAEQCPVKSAEDQLYAITF-RKGLGNPLL--YDGVERVSLQDIKDFADKVYT 181 + A + P A + A F LGN +L + + ++ + + + + Y Sbjct: 121 VILE-EIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITALTREGMAAYHRRRYL 179 Query: 182 KENLEVSGENVVEADLKRFVDESLLSTLPAGKS 214 +N+ ++ V+ D E L P G++ Sbjct: 180 PKNMVLAATGRVDFDRLLAEAERLTEAWPEGEA 212 >4NNZ-A nrPDB Length = 439 Score = 87.2 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 49/352 (13%), Positives = 108/352 (30%), Gaps = 35/352 (9%) Query: 18 TVSARDAPTKISTLAVKVHGGSRYATK--DGVAHLLNRFNFQNTNTRSALKLVRESELLG 75 + D + + GS Y T G++H L F+ + + R LG Sbjct: 18 VIVREDHRAPVVVSQLWYRIGSSYETPGLTGLSHALEHMMFKGSRKLGPGEASRVLRDLG 77 Query: 76 GTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAE 135 + +Y +D LP + AD + + + + + Sbjct: 78 AEENAFTTDDYTAYYQVLARDRLPVALEMEADRMAHLSLPVDQFKSEIEVIKEERRLRTD 137 Query: 136 QCPVKSAEDQLYAITF-RKGLGNPLL--YDGVERVSLQDIKDFADKVYTKENLEVSGEN- 191 P A ++ A + G P + ++R+++ D++ + + Y N + Sbjct: 138 DNPNALAFERFKAAAYPASGYHTPTIGWMADLQRMTIDDLRHWYESWYAPNNATLVVVGD 197 Query: 192 VVEADLKRFVDESLLST----LPAGKSLVSKSEP-----KFFLGEENRVRFIGDSVAAIG 242 V ++K LP + + +EP K ++ + +G +V ++G Sbjct: 198 VTADEVKTLAKRYFGEIPWRQLPPARKPLELAEPGERRLKLYVRTQLPNLIMGFNVPSLG 257 Query: 243 IPVNKASLAQYEVLANYLTSALS-----------ELSGLISSAKLDKFTDGGLFTLF--- 288 N + ++ L S EL S+ LF L Sbjct: 258 SSENPREVNALRLIGALLDGGYSARLASRLERGEELVAGASTYYDAFNRGDSLFVLSATP 317 Query: 289 ------VRDQDSAVVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSS 334 +Q A + + + + ++ + +S+++ Sbjct: 318 NVQKGKTLEQVEAGLWKQLDDLKQNPPSAAEIERVRAQMIAGMVYEKDSIAA 369 >6GIQ-A nrPDB Length = 457 Score = 78.7 bits (192), Expect = 3e-15, Method: Composition-based stats. Identities = 58/377 (15%), Positives = 112/377 (29%), Gaps = 54/377 (14%) Query: 17 LTVSARDAPT-KISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLVRESEL 73 + V+ P+ +++ V G+ +GV++L N+ A K Sbjct: 36 IVVATEHNPSAHTASVGVVFGSGAANENPYNNGVSNLWKNIFLSKENSAVAAK------- 88 Query: 74 LGGTFKSTLDREYITLKATFLKDDLPYYVNALADVL---YKTAFKPHELTESVLPAARYD 130 G S + R++ + + L ++ L + + Sbjct: 89 EGLALSSNISRDFQSYIVSSLPGSTDKSLDFLNQSFIQQKANLLSSSNFEATKKSVLKQV 148 Query: 131 YAVAEQCPVKSAEDQLYAITFRKGLGNPLLYDGVERVSL------QDIKDFADKVYTKEN 184 E + L++ F+ PL + D++ FA+ + N Sbjct: 149 QDFEENDHPNRVLEHLHSTAFQNT---PLSLPTRGTLESLENLVVADLESFANNHFLNSN 205 Query: 185 LEVSGENVV-EADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENR---VRFIGDS--V 238 V G + DL ++ LS K ++ K FLG E R + Sbjct: 206 AVVVGTGNIKHEDLVNSIESKNLSLQTGTKPVLKKKAA--FLGSEVRLRDDTLPKAWISL 263 Query: 239 AAIGIPVNKASLAQYEVLANYLTSALS----------------ELSGLI--SSAKLDKFT 280 A G PVN + ++ A S + + L + + Sbjct: 264 AVEGEPVNSPNYFVAKLAAQIFGSYNAFEPASRLQGIKLLDNIQEYQLCDNFNHFSLSYK 323 Query: 281 DGGLFTLFVRDQDSAVVSSNI---KKIVADLK---KGKDLSPAINYTKLKNAVQNESVSS 334 D GL+ ++ ++ I K L ++ A + KL+ ES + Sbjct: 324 DSGLWGFSTATRNVTMIDDLIHFTLKQWNRLTISVTDTEVERAKSLLKLQLGQLYESGNP 383 Query: 335 PIELNFDAVKDFKLGKF 351 + N + G Sbjct: 384 VNDANLLGAEVLIKGSK 400 >5EUF-A nrPDB Length = 419 Score = 78.7 bits (192), Expect = 4e-15, Method: Composition-based stats. Identities = 63/357 (17%), Positives = 118/357 (33%), Gaps = 42/357 (11%) Query: 23 DAPTKISTLAVKVHGGSRYA--TKDGVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKS 80 + T + + V GSR K G+AH+L NF++T A + + + GG + Sbjct: 25 ENKTGVIEVDVLYKVGSRNEVMGKSGIAHMLEHLNFKSTKNLKAGEFDKIVKRFGGVSNA 84 Query: 81 TLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVK 140 + + + +L + A+ + K E A + P+ Sbjct: 85 STSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFLPERQVVAEERRWRTDNSPIG 144 Query: 141 SAEDQLYAITFR------KGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVE 194 + + + +G D ++ +L+DIK F Y +N V V Sbjct: 145 MLYFRFFNTAYVYHPYHWTPIG---FMDDIQNWTLKDIKKFHSLYYQPKNAIVLVVGDVN 201 Query: 195 ADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRF---------IGDSVAAIGIPV 245 + + V E + K+L K+ P ++ E + + A+G V Sbjct: 202 S---QKVFELTKKHFESLKNLDEKAIPTPYMKEPKQDGARTAVVHKDGVHLEWVALGYKV 258 Query: 246 NKASLAQYEVL-----------ANYLTSALSELSGLISSAK--LDKFTDGGLFTLFVRDQ 292 L +++L S L + L S A + D +F Sbjct: 259 PAFKHKDQVALDALSKLLGEGKSSWLQSELVDKKRLASQAFSHNMQLQDESVFLFIAGGN 318 Query: 293 ---DSAVVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELNFDAVKDF 346 + + I ++ LKKG+ ++ K+ Q S +E + D F Sbjct: 319 PNIKAEALQKEIVALLEKLKKGEITQAELDKIKIN---QKADFISNLESSSDVAGLF 372 >5CIO-A nrPDB Length = 793 Score = 58.3 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 49/251 (19%), Positives = 86/251 (34%), Gaps = 25/251 (9%) Query: 1 MLSAARLQFAQGSVRRLTVSARDAPTKISTLA-VKVHGGSRYATKD--GVAHLLNRFNFQ 57 M AA Q G L V A P + A V++ GS A G+AHLL F+ Sbjct: 24 MTLAASWQLDNG----LAVRAISTPGAEAAAALVRIEAGSFQAPAAWPGLAHLLEHMLFR 79 Query: 58 NTNTRSAL-KLVRESELLGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAF-- 114 + SA L+ ++ GG +T D L + L+D+L Sbjct: 80 GSANFSAQDGLMGWTQAAGGRLNATTQATQTAFFFEVGADPLAEGLARLSDMLAAPQLAA 139 Query: 115 ----KPHELTESVLPAARYDYAVAEQCPVKSA---EDQLYA--ITFRKGLGNPLLYDGVE 165 + E+ ++ R D + + D L+ I R G+ + Sbjct: 140 EAIAQEIEVIDAEYRLLRADGETRCEAAQRQMFSGFDALHRFHIGSRAAFGSDI------ 193 Query: 166 RVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDESLLSTLPAGKSLVSKSEPKFFL 225 Q ++ F Y N+ + + + + + LP+G + ++ P Sbjct: 194 SALQQALRQFHHHYYRAPNMTLWLQGPQSLEQLHALAQRYGGGLPSGSATPPETLPPLAA 253 Query: 226 GEENRVRFIGD 236 G++ + G Sbjct: 254 GQDYTLSLPGA 264 >1Q2L-A nrPDB Length = 939 Score = 56.8 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 37/197 (18%), Positives = 63/197 (31%), Gaps = 8/197 (4%) Query: 17 LTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSAL-KLVRESELLG 75 L VS A +S L V V G+AH L + + L ++ G Sbjct: 33 LLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLAEYLKMHG 92 Query: 76 GTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAF------KPHELTESVLPAARY 129 G+ ++ D LP V+ LAD + + + + L AR Sbjct: 93 GSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNAELTMART 152 Query: 130 DYAVAEQCPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENL-EVS 188 + + + + G L D Q +KDF +K Y+ + V Sbjct: 153 RDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVI 212 Query: 189 GENVVEADLKRFVDESL 205 N +L + ++ Sbjct: 213 YSNKPLPELAKMAADTF 229 >3GO9-A nrPDB Length = 492 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 67/192 (34%), Gaps = 24/192 (12%) Query: 19 VSARDAPTKISTLAVKVHGGSRYAT--KDGVAHLLNRFNFQNTNTRSALKLV----RESE 72 ++ P+ L + V+ GS + G AHLL R ++ + + +L + + Sbjct: 40 LATPQRPSDRIELRLIVNTGSLSENTQEVGFAHLLPRLALMSSASFTPAQLQSLWQQGID 99 Query: 73 LLGGTFKSTLDREYITLKATFLK---DDLPYYVNALADVLYKTAFKPHELTESVLPAARY 129 + ++ + D L + L+D A + ++ A Sbjct: 100 NERPLPPAITSYDFTLYSLSLPNNRPDLLKDALAWLSDTAGNLAVSEQTVNAALNTA--- 156 Query: 130 DYAVAEQCPVKSAEDQLYAITFRKGL-GNPLLYDGVER-----VSLQDIKDFADKVYTKE 183 P+ + + +R L G+ L+ + V ++ +K F + YT + Sbjct: 157 ------TDPIATFPQNIQEPWWRYRLKGSSLIGHDPGQPVTQPVDVEKLKQFYQQWYTPD 210 Query: 184 NLEVSGENVVEA 195 + + V++ Sbjct: 211 AMTLYVVGNVDS 222 >3WKF-A nrPDB Length = 412 Score = 33.7 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 28/96 (29%), Gaps = 2/96 (2%) Query: 148 AITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDESLLS 207 A +R+ LG PL + ER ++ F D + V+ + K +S Sbjct: 72 AAAYRQ-LGTPLYREMAERAYRYFVRHFVDAEHGGVYWMVAADGRPLDTRKHVYAQSFAI 130 Query: 208 TLPAGKSLVSKSEPKFFLGEENRVRF-IGDSVAAIG 242 + + E L + G Sbjct: 131 YALSEWHRATGGEAALALARSIYDLIETHCADRVHG 166 >1D0N-A nrPDB Length = 729 Score = 31.7 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 15/51 (29%) Query: 33 VKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLD 83 + V G+ A K G LL Q + E LGG Sbjct: 551 LWVGAGASEAEKTGAQELLRVLRAQPVQVAEGSEPDSFWEALGGKATYRTS 601 >4RJW-A nrPDB Length = 429 Score = 31.0 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 35/87 (40%), Gaps = 4/87 (4%) Query: 262 SALSELSGLISSAKLDKFTDGGLFTL---FVRDQDSAVVSSNIKKIVADLKKGKDLSPAI 318 + G +S++ + D ++ L + SA +K+ AD KD+ Sbjct: 255 NGNRATFGGVSNSPAGSYKDDSVWGLEGAWAMGPFSAQAEYLARKLKADDNAYKDIKAKG 314 Query: 319 NYTKLKNAVQNESVSSPIE-LNFDAVK 344 Y +L + ES +E FD+VK Sbjct: 315 YYAQLAYTLTGESRQYKLEGAKFDSVK 341 >4R86-A nrPDB Length = 304 Score = 29.8 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 28/187 (14%), Positives = 65/187 (34%), Gaps = 20/187 (10%) Query: 191 NVVEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASL 250 L+ V + + + +L+ S ++ G + + Sbjct: 20 GASAQTLENTVTQVIEQNMTGLDNLMYMS---------SQSSGTGQATITLSFIAGTDPD 70 Query: 251 AQYEVLANYLTSALSELSGLISSA--KLDKFTDGGLFTLFVRDQDSAV--------VSSN 300 + + N L SA+ +L + + K D + T+ D ++ V+SN Sbjct: 71 EAVQQVQNQLQSAMRKLPQAVQDQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASN 130 Query: 301 IKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVS 360 I+ ++ + D+ + ++ + ++S D V D + +AVG + Sbjct: 131 IQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKD-VTDAIESQNAQIAVGQLG 189 Query: 361 NLPYLDE 367 P +D+ Sbjct: 190 GTPSVDK 196 >3QQ2-A nrPDB Length = 284 Score = 29.4 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 22/64 (34%), Gaps = 2/64 (3%) Query: 15 RRLTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELL 74 RR + + + + G RY +G+ ++ T R L+ R L Sbjct: 146 RRFELPNDWFAEPQAEVMLWRTSGKRYRASNGLRVKVD--ANTATLGRLGLRFGRRIALA 203 Query: 75 GGTF 78 GG Sbjct: 204 GGNI 207 >1NPH-A nrPDB Length = 329 Score = 28.7 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 21/69 (30%), Gaps = 3/69 (4%) Query: 33 VKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREYITLKAT 92 + V G+ A K LL Q+ + E LGG T R LK Sbjct: 164 LWVGAGASEAEKTAAQELLKVLRSQHVQVEEGSEPDGFWEALGGK---TSYRTSPRLKDK 220 Query: 93 FLKDDLPYY 101 + P Sbjct: 221 KMDAHPPRL 229 >4WAI-A nrPDB Length = 121 Score = 28.7 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 22/56 (39%) Query: 131 YAVAEQCPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLE 186 + + + DQL+ + N +L + +VS + DF YTK L Sbjct: 29 KEIVMKELLDRYMDQLHMACTCQVCQNDVLALSLNKVSPSYVTDFKKIAYTKAELV 84 >1NL3-A nrPDB Length = 922 Score = 28.7 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 26/129 (20%), Positives = 45/129 (34%), Gaps = 12/129 (9%) Query: 20 SARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELL----G 75 ++++A I + V G R+ ++ L R Q S L EL+ G Sbjct: 567 ASKEAKEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDELMRRFNG 626 Query: 76 GTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFK-PHELTESVLPAARYDYAVA 134 ++ L R L DD+P + + + + E +YD + Sbjct: 627 AALETLLTRLN-------LPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRKNVLKYDEVMN 679 Query: 135 EQCPVKSAE 143 +Q V AE Sbjct: 680 QQRKVIYAE 688 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.120 0.272 Lambda K H 0.267 0.0369 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,180,442 Number of Sequences: 36641 Number of extensions: 350559 Number of successful extensions: 1214 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 36 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 1109 Number of HSP's gapped (non-prelim): 61 length of query: 368 length of database: 10,336,785 effective HSP length: 98 effective length of query: 270 effective length of database: 6,745,967 effective search space: 1821411090 effective search space used: 1821411090 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.5 bits)