BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P07236 (462 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4YYE-A nrPDB 912 0.0 4P3N-A nrPDB 365 e-101 1QF6-A nrPDB 295 4e-80 4HWO-A nrPDB 293 1e-79 1NYR-A nrPDB 267 8e-72 3A31-A nrPDB 163 1e-40 5UCM-A nrPDB 52 4e-07 2J3M-A nrPDB 52 8e-07 3IAL-A nrPDB 49 6e-06 2I4O-A nrPDB 47 1e-05 6NAB-A nrPDB 47 2e-05 2ZR2-A nrPDB 46 3e-05 6H9X-A nrPDB 40 0.001 3ERR-A nrPDB 40 0.002 1SER-A nrPDB 39 0.004 2DQ3-A nrPDB 38 0.012 2CIM-A nrPDB 37 0.016 4NCX-A nrPDB 37 0.017 6GIR-A nrPDB 33 0.18 4F3Y-A nrPDB 32 0.62 5F9Y-A nrPDB 30 2.0 4KRY-A nrPDB 30 2.4 6BLJ-A nrPDB 30 2.5 3Q6N-A nrPDB 30 2.7 4RQF-A nrPDB 30 3.0 3QO8-A nrPDB 29 3.9 3LSS-A nrPDB 29 5.6 3ADF-A nrPDB 28 7.3 >4YYE-A nrPDB Length = 460 Score = 912 bits (2357), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/437 (100%), Positives = 437/437 (100%) Query: 26 ATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFG 85 ATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFG Sbjct: 24 ATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFG 83 Query: 86 FNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDR 145 FNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDR Sbjct: 84 FNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDR 143 Query: 146 SYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDI 205 SYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDI Sbjct: 144 SYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDI 203 Query: 206 VYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPG 265 VYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPG Sbjct: 204 VYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPG 263 Query: 266 DGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGS 325 DGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGS Sbjct: 264 DGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGS 323 Query: 326 IERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPV 385 IERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPV Sbjct: 324 IERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPV 383 Query: 386 PLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKL 445 PLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKL Sbjct: 384 PLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKL 443 Query: 446 TMSQIWEKFIELEKNYK 462 TMSQIWEKFIELEKNYK Sbjct: 444 TMSQIWEKFIELEKNYK 460 >4P3N-A nrPDB Length = 415 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 186/420 (44%), Positives = 271/420 (64%), Gaps = 34/420 (8%) Query: 42 VSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE 101 + + Q+L+ LSPGS FFLP GA I+N LIEF++ + + K GF EVVTP I+ LW Sbjct: 18 IGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYR-KRGFQEVVTPNIFNSRLWM 76 Query: 102 KSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLH 161 SGHW++Y+++MF E EKE + LKPMNCPGHCL+F + RS+ ELPLR +DF LH Sbjct: 77 TSGHWQHYSENMFSFEV---EKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLH 133 Query: 162 RNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAE 221 RNE SGAL+GLTR+R+F QDD HIFC Q++ EI L + VY+ +F F Sbjct: 134 RNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYS-VFGF-------- 184 Query: 222 SNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDH 281 ++ +N STRP+ F+GD++VW+ AE+ L+ L E G+ W+LN GDGAFYGPK+DI + D Sbjct: 185 -SFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDA 243 Query: 282 LRKTHQVATIQLDFQLPERFDLKFKDQD-NSYKRPIMIHRATFGSIERFMALLIDSNEGR 340 + + HQ ATIQLDFQLP RF+L + D + KRP+++HRA GS+ER +A+L ++ G+ Sbjct: 244 IGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGK 303 Query: 341 WPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIR- 399 WPFWL+P Q +++PV C +K+R + +D F D+D+ Sbjct: 304 WPFWLSPRQVMVVPVGP-------TCDEYAQKVRQQ----------FHDAKFMADIDLDP 346 Query: 400 NEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEK 459 + +I++A L Y+++++VG++E NIR RDN+ E+ T+S+ E+ +L++ Sbjct: 347 GCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGER-TISETIERLQQLKE 405 >1QF6-A nrPDB Length = 642 Score = 295 bits (754), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 166/461 (36%), Positives = 248/461 (53%), Gaps = 38/461 (8%) Query: 1 MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTSM-------VSQRQDLFMTDP 53 MK W N + Y T A K A +A + + ++ DL+ Sbjct: 199 MKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQE 258 Query: 54 LSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDM 113 +PG +F+ +G IF +L F++ + K ++ + EV P + + LWEK+GHW+NY D M Sbjct: 259 EAPGMVFWHNDGWTIFRELEVFVRSKLK-EYQYQEVKGPFMMDRVLWEKTGHWDNYKDAM 317 Query: 114 FKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 F TT E EY +KPMNCPGH IF + +SY +LPLR ++F HRNE SG+L GL Sbjct: 318 F---TTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLM 374 Query: 174 RLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPD 233 R+R F QDD HIFCT Q++ E+ ++L+ +Y+ F F K + STRP+ Sbjct: 375 RVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYS-TFGFEK--------IVVKLSTRPE 425 Query: 234 HFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQL 293 IG ++W+ AE L LEE+ P++ G+GAFYGPK++ + D L + Q T+QL Sbjct: 426 KRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQL 485 Query: 294 DFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVII 353 DF LP R + +DN K P+MIHRA GS+ERF+ +L + G +P WL P Q VI+ Sbjct: 486 DFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIM 545 Query: 354 PVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILK 413 + T Q + NEL L++ V D+RNE +G++I+ L+ Sbjct: 546 NI-----------TDSQSEYVNELTQ------KLSNAGIRVKADLRNEKIGFKIREHTLR 588 Query: 414 NYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKF 454 Y+++ GD+EV+ K +R R K + ++++ EK Sbjct: 589 RVPYMLVCGDKEVESGKVAVRTRRG-KDLGSMDVNEVIEKL 628 >4HWO-A nrPDB Length = 411 Score = 293 bits (750), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 156/413 (37%), Positives = 235/413 (56%), Gaps = 31/413 (7%) Query: 42 VSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE 101 + ++ DL+ +PG +F+ +G IF +L F++ + K ++ + EV P + + LWE Sbjct: 8 IGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLK-EYQYQEVKGPFMMDRVLWE 66 Query: 102 KSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLH 161 K+GHW+NY D MF TT E EY +KPMNCPGH IF + +SY +LPLR ++F H Sbjct: 67 KTGHWDNYKDAMF---TTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCH 123 Query: 162 RNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAE 221 RNE SG+L GL R+R F QDD HIFCT Q++ E+ ++L+ +Y+ F F K Sbjct: 124 RNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYS-TFGFEK------ 176 Query: 222 SNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDH 281 + STRP+ IG ++W+ AE L LEE+ P++ G+GAFYGPK++ + D Sbjct: 177 --IVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDC 234 Query: 282 LRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRW 341 L + Q T+QLDF LP R + +DN K P+MIHRA GS+ERF+ +L + G + Sbjct: 235 LDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFF 294 Query: 342 PFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE 401 P WL P Q VI+ + T Q + NEL L++ V D+RNE Sbjct: 295 PTWLAPVQVVIMNI-----------TDSQSEYVNELTQ------KLSNAGIRVKADLRNE 337 Query: 402 PVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKF 454 +G++I+ L+ Y+++ GD+EV+ K +R R K + ++++ EK Sbjct: 338 KIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRG-KDLGSMDVNEVIEKL 389 >1NYR-A nrPDB Length = 645 Score = 267 bits (682), Expect = 8e-72, Method: Compositional matrix adjust. Identities = 150/399 (37%), Positives = 224/399 (56%), Gaps = 32/399 (8%) Query: 42 VSQRQDLFMTDPL-SPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLW 100 + + +LF L G +LPNGA I + IE + ++ G++ V TP++ L+ Sbjct: 246 IGKELELFTNSQLVGAGLPLWLPNGATI-RREIERYIVDKEVSMGYDHVYTPVLANVDLY 304 Query: 101 EKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPL 160 + SGHW++Y +DMF DE E L+PMNCP H +I+ K SY ELP+R ++ + Sbjct: 305 KTSGHWDHYQEDMFPPMQLDE-TESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTM 363 Query: 161 HRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGA 220 HR EASGA+SGL R+R +D HIF P Q+K E + +I VY K F F Sbjct: 364 HRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVY-KDFGF------- 415 Query: 221 ESNYFINFSTR----PDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDI 276 +Y S R + + D +WN AE +LKE +E G ++ G+ AFYGPKLD+ Sbjct: 416 -EDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDV 474 Query: 277 MVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDS 336 V + K ++T QLDF LPERFDL + QD + RP++IHR ++ERF+A L + Sbjct: 475 QVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEE 534 Query: 337 NEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDL 396 +G +P WL P Q IIPVN +D+ ++L++EL++ + V + Sbjct: 535 TKGAFPTWLAPKQVQIIPVN------VDLHYDYARQLQDELKSQGV----------RVSI 578 Query: 397 DIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRE 435 D RNE +GY+I+ A ++ Y I+VGD+EV+ + N+R+ Sbjct: 579 DDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQ 617 >3A31-A nrPDB Length = 471 Score = 163 bits (413), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 105/309 (33%), Positives = 161/309 (52%), Gaps = 28/309 (9%) Query: 85 GFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIF---G 141 G+ V TP+I L++ SGH E Y ++M+ D E E+ +KPMNCP H L+F Sbjct: 67 GYYVVETPIIASTELFKVSGHIEFYRNNMY---LFDIEGHEFAVKPMNCPYHILLFLNEV 123 Query: 142 KKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLK 201 K RS LP + +F +HR E SG++ GL R+R F QDD HI +V +++ + Sbjct: 124 AKHRSKLPLPFKVFEFGRVHRYEPSGSIYGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFE 183 Query: 202 LIDIVYNKIFPFVKGGSGAESNYF---INFSTRP---DHFIGDLKVWNHAEQVLKEILEE 255 + +V ++F G S F ++ S + F+G + W AE+ L+E Sbjct: 184 EMKLVLERLFKL-----GVSSETFKVRLSMSDKSLIGKEFMGSKEEWEGAEEALREAASR 238 Query: 256 SGKPWKLN----PGDGAFYGPKLD-IMVTDH--LRKTHQVATIQLDFQLPERFDL-KFKD 307 + + ++ G+ AFYGPKLD IM+ + + K Q+ TIQ DF LP RF L Sbjct: 239 INEKYGIDIVELEGEAAFYGPKLDFIMMVEESGVSKEWQMGTIQFDFNLPRRFRLYDVVR 298 Query: 308 QDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTK---NVQQLD 364 ++ + +IHRA GSIERF+ + ++ GR PF L P Q +I V T + + D Sbjct: 299 EEFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLAPIQFAVIAVKTGGEVDREIED 358 Query: 365 MCTALQKKL 373 + +++ K L Sbjct: 359 LASSIAKGL 367 >5UCM-A nrPDB Length = 579 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 7/162 (4%) Query: 50 MTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENY 109 M L+ G +LP G ++ K +E + ++ G EV+ P + LW++SG WE Y Sbjct: 39 MIRRLASGLYTWLPMGLRVLRK-VETIVREEMNAAGALEVLMPAVQPAELWQESGRWEQY 97 Query: 110 ADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGAL 169 ++ +++ D + E+ + P + + + SY +LP+ F R+E Sbjct: 98 GPELLRLK--DRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRF 155 Query: 170 SGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIF 211 GL R R+F D + F + ++ + Y+KIF Sbjct: 156 -GLMRGREFIMKDAYSFHLSQDSLQQTYDGMYQ---AYSKIF 193 >2J3M-A nrPDB Length = 572 Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 39/158 (24%), Positives = 75/158 (47%), Gaps = 7/158 (4%) Query: 54 LSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDM 113 ++ G +LP ++ KL M+ ++ K E++ P + LW++SG +E Y ++ Sbjct: 35 VAAGIYSYLPLANRVLEKLKTIMR-EEFEKIDAVEMLMPALLPAELWKESGRYETYGPNL 93 Query: 114 FKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 ++++ D +Y L P + + + SY LPL +R+E + SGL Sbjct: 94 YRLK--DRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKR-SRSGLL 150 Query: 174 RLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIF 211 R R+F DG+ F ++ + S + + Y++IF Sbjct: 151 RGREFIMKDGYSFHAD---EASLDQSYRDYEKAYSRIF 185 >3IAL-A nrPDB Length = 518 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 71/319 (22%), Positives = 126/319 (39%), Gaps = 57/319 (17%) Query: 57 GSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEK-SGHWENYADDMFK 115 G + F P G + N ++ + ++ K G ++++ P + ++ +K S H + + + F Sbjct: 46 GCVVFRPYGFFMENAIMRLCE-EEYAKVGISQILFPTVIPESFLKKESDHIKGFEAECFW 104 Query: 116 VETTDEE--KEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 VE + +E L+P + +F K RSY +LPL+ + R+E L Sbjct: 105 VEKGGLQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKNT-KPLI 163 Query: 174 RLRKFHQDDGHIF-CTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRP 232 R+R+ H ++ H T S++ + K+ID +++ F KG Sbjct: 164 RVREIHWNEAHCCHATAEDAVSQLSDYWKVIDTIFSDELCF-KG---------------- 206 Query: 233 DHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQ 292 Q L+ + W P GA Y D+++ + Q A I Sbjct: 207 --------------QKLRRVC------WDRFP--GADYSEVSDVVMP--CGRVLQTAGIH 242 Query: 293 -LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPFWLNP 347 L + FD+ + ++ N P + G R +A + DS P + P Sbjct: 243 NLGQRFSSTFDILYANKANESVHPYL---TCAGISTRVLACALSIHGDSGGLVLPPLIAP 299 Query: 348 YQAVIIPVNT--KNVQQLD 364 VIIP+ KN Q+ D Sbjct: 300 IHVVIIPIGCGKKNNQESD 318 >2I4O-A nrPDB Length = 458 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 4/146 (2%) Query: 55 SPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMF 114 + G +LP G ++ K+ + ++ +Q + G E++ P + LW +SG ++ Y +M Sbjct: 56 AAGIYAWLPLGHRVLKKIEQIVREEQN-RAGAIELLMPTLQLADLWRESGRYDAYGPEML 114 Query: 115 KVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTR 174 ++ D K E P N IF +SY LPL R+E G+ R Sbjct: 115 RI--ADRHKRELLYGPTNEEMITEIFRAYIKSYKSLPLNLYHIQWKFRDEQRPRF-GVMR 171 Query: 175 LRKFHQDDGHIFCTPSQVKSEIFNSL 200 R+F D + F + +N + Sbjct: 172 GREFLMKDAYSFDVDEAGARKSYNKM 197 >6NAB-A nrPDB Length = 513 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/189 (24%), Positives = 90/189 (47%), Gaps = 11/189 (5%) Query: 57 GSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPL-IYKKTLWEKSGHWENYADDMFK 115 G F PN ++ + +F + K K G V+ PL + K+ L + H E ++ ++ Sbjct: 43 GCYIFRPNCWFVWESVQKFFDAEIK-KLGVQNVMFPLFVTKRALETEKDHVEGFSPEVAW 101 Query: 116 VETTDEE--KEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 V + +E L+P + + K +S+ +LPL+ + ++ + R E A+ Sbjct: 102 VTKSGNSDLQEPIALRPTSETIMYPSYAKWIQSHRDLPLKLNQWTNVVRWEFKHAVP-FI 160 Query: 174 RLRKFHQDDGH-IFCTPSQVKSEIFNSLKLIDIVYNKIF--PFVKGGSGAESNYF--INF 228 R R+F+ +GH F + + E+F L+L VY ++ P +K G+ E+ F ++ Sbjct: 161 RSREFYWQEGHSAFKSKEEADEEVFTILELYKRVYEELLAVPVIK-GTKTENEKFAGADY 219 Query: 229 STRPDHFIG 237 +T + FI Sbjct: 220 TTTVETFIA 228 >2ZR2-A nrPDB Length = 455 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Query: 47 DLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHW 106 D +S ++L N I + + L + + GF V+ P + ++ + E S + Sbjct: 173 DFARAAKVSGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSF 232 Query: 107 ENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEAS 166 E++ D ++KVE D P+ I KD LPL + SP R EA Sbjct: 233 EDFEDVIYKVEDEDLYLIPTAEHPLAGMHANEILDGKD-----LPLLYVGVSPCFRKEAG 287 Query: 167 GA---LSGLTRLRKFHQDDGHIFCTPSQ 191 A G+ R+ +FH+ + ++ P + Sbjct: 288 TAGKDTKGIFRVHQFHKVEQFVYSRPEE 315 >6H9X-A nrPDB Length = 430 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 32/213 (15%) Query: 57 GSMFFLPNG--AKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMF 114 GS F + G A++ L +FM + G++E P + + +G +A D+F Sbjct: 159 GSRFVVMKGQLARLHRALAQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF 218 Query: 115 KVETTDEEKEE--YGLKP-MNCPGHCLIFGKKDRSYNE--LPLRFSDFSPLHRNEASG-- 167 +EE + Y L P P L+ +D +E LP++ + +P R+EA Sbjct: 219 HTRPLEEEADSSNYALIPTAEVPLTNLV---RDEIIDEDDLPIKMTAHTPCFRSEAGSYG 275 Query: 168 -ALSGLTRLRKFHQDDGHIFCTP-------SQVKSEIFNSLKLIDIVYNKIFPFVKGGSG 219 GL R+ +F + + P ++ L+L+ + Y K+ G G Sbjct: 276 RDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKV-ALCTGDMG 334 Query: 220 AESNYFINFSTRPDHFIGDLKVWNHAEQVLKEI 252 FS + DL+VW A+ +EI Sbjct: 335 --------FSACKTY---DLEVWVPAQNTYREI 356 >3ERR-A nrPDB Length = 536 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 14/112 (12%) Query: 85 GFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTD---EEKEEYGLKPMNCPGHCLIFG 141 GF + P ++ + +GH+ Y D ++ + TD E L ++ G L Sbjct: 293 GFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHS-GEIL--- 348 Query: 142 KKDRSYNELPLRFSDFSPLHRNEASG---ALSGLTRLRKFHQDDGHIFCTPS 190 Y LPLR++ ++P R+EA + GL R+ +FH+ + ++ S Sbjct: 349 ----PYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEAS 396 >1SER-A nrPDB Length = 421 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 14/112 (12%) Query: 85 GFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTD---EEKEEYGLKPMNCPGHCLIFG 141 GF + P ++ + +GH+ Y D ++ + TD E L ++ G L Sbjct: 184 GFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVLNALHS-GEIL--- 239 Query: 142 KKDRSYNELPLRFSDFSPLHRNEASG---ALSGLTRLRKFHQDDGHIFCTPS 190 Y LPLR++ ++P R+EA + GL R+ +FH+ + ++ S Sbjct: 240 ----PYEALPLRYAGYAPAFRSEAGSFGKDVRGLMRVHQFHKVEQYVLTEAS 287 >2DQ3-A nrPDB Length = 425 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 59/281 (20%), Positives = 111/281 (39%), Gaps = 61/281 (21%) Query: 65 GAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKE 124 GA++ LI FM L K G+ E+ P + K + +G + +D++K E ++ Sbjct: 171 GARLERALINFM-LDLHTKKGYKEICPPHLVKPEILIGTGQLPKFEEDLYKCE-----RD 224 Query: 125 EYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGH 184 L P ++ ++ LP+ + ++P +R EA + + + HQ Sbjct: 225 NLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGAYGKDIRGIIRQHQ---- 280 Query: 185 IFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDL-KVWN 243 F+ ++L+ IV+ PD +L K+ Sbjct: 281 ------------FDKVELVKIVH------------------------PDTSYDELEKLVK 304 Query: 244 HAEQVLKEILEESGKPWK---LNPGDGAFYGPKL-DIMV----TDHLRKTHQVATIQLDF 295 AE+VL+ + G P++ L GD F K DI V + R+ + + DF Sbjct: 305 DAEEVLQLL----GLPYRVVELCTGDLGFSAAKTYDIEVWFPSQNKYREISSCSNCE-DF 359 Query: 296 QLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDS 336 Q R + +FKD R + + ++ R +A ++++ Sbjct: 360 Q-ARRMNTRFKDSKTGKNRFVHTLNGSGLAVGRTLAAILEN 399 >2CIM-A nrPDB Length = 522 Score = 37.4 bits (85), Expect = 0.016, Method: Compositional matrix adjust. Identities = 33/154 (21%), Positives = 59/154 (38%), Gaps = 28/154 (18%) Query: 55 SPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMF 114 S G P A+IF + + + G+ E++ P + +W KSGH + +++ Sbjct: 220 SRGQWIHGPQSARIFRTFEKIVLEELLEPLGYREMIFPKLVTWEVWMKSGHAKGVYPEIY 279 Query: 115 KV---ETTD----EEKEEY---------------------GLKPMNCPGHCLIFGKKDRS 146 V +T D EE +Y G+ CP + + Sbjct: 280 YVCPPQTRDPDYWEEVADYYKVTHEVPTKLIKEKIAEPIGGMCYAQCPPFWMYVAGETLP 339 Query: 147 YNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQ 180 E+P++ D S SG + G+ R+ +FH+ Sbjct: 340 NEEIPVKVFDRSGTSHRYESGGIHGIERVDEFHR 373 >4NCX-A nrPDB Length = 506 Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust. Identities = 89/434 (20%), Positives = 162/434 (37%), Gaps = 88/434 (20%) Query: 23 TRKATKNASS-ATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQK 81 T K +N S T + S + + D+ L P + + FNK I+ + ++ Sbjct: 15 TSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENS 74 Query: 82 FKFGFNEVVTPLIYKKTLWEKS-GHWENYADDMFKVETTDEEK--EEYGLKPMNCPGHCL 138 + PL K EK H E ++ ++ V + EE ++P + Sbjct: 75 Y--------FPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYS 126 Query: 139 IFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSE--- 195 +F K RSY +LPL+ + ++ + R E + R R+F +GH T + + E Sbjct: 127 VFPKWIRSYRDLPLKLNQWNTVVRWEFKQP-TPFIRTREFLWQEGH---TAHKNEEEAVK 182 Query: 196 -IFNSLKLIDIVYNKIF--PFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEI 252 +F+ L L Y + P +KG +K Sbjct: 183 LVFDILDLYRRWYEEYLAVPIIKG--------------------------------IKSE 210 Query: 253 LEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSY 312 E+ G GA + + ++++ R + L + F ++F+D+ N Sbjct: 211 GEKFG---------GANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDE-NEV 260 Query: 313 KRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNP----YQAVIIPVNTKNVQQLDM--- 365 K+ +H+ ++G R + ++I ++ L P Y+ VI+P+ K + + Sbjct: 261 KQ--YVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSY 318 Query: 366 CTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE-PVGYRIKSAILKNYSYLIIVGDE 424 C ++K L+N N D R GY+ L+ I VG + Sbjct: 319 CKDIEKILKNA--------------QINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPK 364 Query: 425 EVQLQKYNIRERDN 438 ++Q I RDN Sbjct: 365 DLQNNSCVIVRRDN 378 >6GIR-A nrPDB Length = 456 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 6/138 (4%) Query: 60 FFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETT 119 FFL + N+ + L K GF + P +K + K + ++++KV T Sbjct: 170 FFLKGDGLMLNQALINFGLTFLKKRGFTGLQPPFFMRKDVMAKCAQLAQFDEELYKV--T 227 Query: 120 DEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGA---LSGLTRLR 176 E ++Y + P C + ELPLR++ +S R EA G+ R+ Sbjct: 228 GEGDDKYLIATAEQP-LCAYHIDEWIHPTELPLRYAGYSSCFRKEAGSHGRDTLGIFRVH 286 Query: 177 KFHQDDGHIFCTPSQVKS 194 +F + + P++ S Sbjct: 287 QFEKIEQFCITGPNENAS 304 >4F3Y-A nrPDB Length = 272 Score = 32.0 bits (71), Expect = 0.62, Method: Compositional matrix adjust. Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 11/85 (12%) Query: 241 VWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPE- 299 V + L L+ +G P +L GAF G + + +TD + + A +DF LPE Sbjct: 27 VLAAPDATLVGALDRTGSP-QLGQDAGAFLGKQTGVALTDDIERVCAEADYLIDFTLPEG 85 Query: 300 ---------RFDLKFKDQDNSYKRP 315 R D+K + P Sbjct: 86 TLVHLDAALRHDVKLVIGTTGFSEP 110 >5F9Y-A nrPDB Length = 511 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 35/158 (22%), Positives = 69/158 (43%), Gaps = 16/158 (10%) Query: 54 LSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDM 113 L P S F +F++ I+ +Q N + +K L + H E ++ ++ Sbjct: 51 LRPWSYFIWETIQSVFDQKIKQHDVQ-------NAYFPIFVTQKKLETEKDHVEGFSPEV 103 Query: 114 FKVETTDEE--KEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSG 171 V + + E ++P + F K RS+ +LPL+ + ++ + R E + Sbjct: 104 AWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHP-TP 162 Query: 172 LTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNK 209 R R+F +GH T + E +L+++DI+ N+ Sbjct: 163 FIRTREFLWQEGH---TAHSTRKE---ALEMVDIILNE 194 >4KRY-A nrPDB Length = 333 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 5/70 (7%) Query: 8 WHCSRNALWNRAFYSTRKATKNASSATPATMTSMVSQRQD-----LFMTDPLSPGSMFFL 62 W + R +Y+ + NA + AT MV + LF P SP ++F+L Sbjct: 45 WPATGTIAEQRQYYTLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYL 104 Query: 63 PNGAKIFNKL 72 G I L Sbjct: 105 HGGGFILGNL 114 >6BLJ-A nrPDB Length = 485 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 11/124 (8%) Query: 83 KFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGK 142 K G+ + TP K +K + ++++ V T E +++Y + P K Sbjct: 238 KKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTV--TGEGEDKYLIATSEQPIAAFHLEK 295 Query: 143 K-DRSYNELPLRFSDFSPLHRNEASGALS----GLTRLRKFHQDDGHIFCTPSQVKS-EI 196 + D S ELP+++ S R E GA G+ R+ +F + + + +P KS E+ Sbjct: 296 RFDES--ELPIKYCGMSTCFRKEV-GAHGKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEM 352 Query: 197 FNSL 200 F+ + Sbjct: 353 FDEM 356 >3Q6N-A nrPDB Length = 448 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 57/218 (26%), Positives = 92/218 (42%), Gaps = 41/218 (18%) Query: 256 SGKP-WKLNPGD------GAFYGPKLDIMVTDHLRKTHQVATIQLDFQ----LPER--FD 302 + KP W NP D G FY L DHL H QL+F+ +P R FD Sbjct: 2 ATKPIWTRNPDDITNEEYGEFYKS-LTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFD 60 Query: 303 LKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVI----IPVNTK 358 L F+++ + + R ++D+ E P +LN + V+ +P+N Sbjct: 61 L-FENRKKKNNIKLYVRRV----------FIMDNCEELIPEYLNFIRGVVDSEDLPLNIS 109 Query: 359 N--VQQLDMCTALQKKL-RNELE-----ADDMEPVP--LNDWHFNVDLDIRNEPVGYRIK 408 +QQ + ++K L + LE A+D E + N+ L I + + Sbjct: 110 REMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKL 169 Query: 409 SAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLT 446 S +L+ Y+ GDE V L+ Y R ++N+K +T Sbjct: 170 SELLRYYTS--ASGDEMVSLKDYCTRMKENQKHIYYIT 205 >4RQF-A nrPDB Length = 522 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 33/157 (21%), Positives = 67/157 (42%), Gaps = 15/157 (9%) Query: 57 GSMFFLPNGAKIF--NKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMF 114 GS + G +F LI++ L+ G+ + TP +K + ++ + ++++ Sbjct: 190 GSRGYFLKGVLVFLEQALIQYA-LRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELY 248 Query: 115 KVETTDEEK-------EEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASG 167 KV EK E+Y + P L + R +LP++++ S R E Sbjct: 249 KVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRP-EDLPIKYAGLSTCFRQEVGS 307 Query: 168 A---LSGLTRLRKFHQDDGHIFCTPSQVKS-EIFNSL 200 G+ R+ +F + + ++ +P KS E+F + Sbjct: 308 HGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEM 344 >3QO8-A nrPDB Length = 485 Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust. Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 6/136 (4%) Query: 60 FFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETT 119 +FL N N+ + L G+ + P++ K + K+ + ++++KV Sbjct: 178 YFLRNYGVFLNQALINYGLSFLSSKGYVPLQAPVMMNKEVMAKTAQLSQFDEELYKVIDG 237 Query: 120 DEEKEEYGLKPMNCPGHCLIFGKKDRSYNE-LPLRFSDFSPLHRNEASGALS---GLTRL 175 ++EK Y + P G+ S E LP+R++ +S R EA G+ R+ Sbjct: 238 EDEK--YLIATSEQPISAYHAGEWFESPAEQLPVRYAGYSSCFRREAGSHGKDAWGIFRV 295 Query: 176 RKFHQDDGHIFCTPSQ 191 F + + + P + Sbjct: 296 HAFEKIEQFVLTEPEK 311 >3LSS-A nrPDB Length = 484 Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust. Identities = 28/147 (19%), Positives = 58/147 (39%), Gaps = 12/147 (8%) Query: 54 LSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDM 113 ++ G + L G + L K G+ P + + + + +++ Sbjct: 195 MAGGRSYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVMGEVAQLSQFDEEL 254 Query: 114 FKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNEL--PLRFSDFSPLHRNEASGALS- 170 ++V ++K M + + R + EL PL+++ S R EA GA Sbjct: 255 YQVSGDGDKKYLIATSEMPIAAY-----HRGRWFTELKEPLKYAGMSTCFRKEA-GAHGR 308 Query: 171 ---GLTRLRKFHQDDGHIFCTPSQVKS 194 G+ R+ +F + + + C+P Q +S Sbjct: 309 DTLGIFRVHQFDKIEQFVVCSPRQEES 335 >3ADF-A nrPDB Length = 228 Score = 28.5 bits (62), Expect = 7.3, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 8/117 (6%) Query: 36 ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIY 95 T TS +S R D F D G+ F PNG + K +++ +K + + V+ + Sbjct: 104 CTATSNISMRGDCFFYDIRFDGTNF-PPNGPVMQKKTLKWEPSTEKM-YVEDGVLKGDVN 161 Query: 96 KKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPL 152 + L E GH+ +TT + K+E L + H + K D+ YN++ L Sbjct: 162 MRLLLEGGGHYR------CDFKTTYKAKKEVRLPDAHKIDHRIEILKHDKDYNKVKL 212 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4YYE-A nrPDB 624 e-179 1QF6-A nrPDB 574 e-164 4HWO-A nrPDB 508 e-144 4P3N-A nrPDB 484 e-137 1NYR-A nrPDB 477 e-135 3A31-A nrPDB 298 3e-81 3IAL-A nrPDB 272 2e-73 6NAB-A nrPDB 199 2e-51 2I4O-A nrPDB 181 5e-46 5UCM-A nrPDB 171 5e-43 2J3M-A nrPDB 159 2e-39 6H9X-A nrPDB 157 8e-39 2ZR2-A nrPDB 145 4e-35 3ERR-A nrPDB 121 7e-28 Sequences not found previously or not previously below threshold: 1NJ2-A nrPDB 168 6e-42 4K87-A nrPDB 167 1e-41 1NJ8-A nrPDB 165 3e-41 4NCX-A nrPDB 162 4e-40 5F9Y-A nrPDB 161 7e-40 6MN8-A nrPDB 161 8e-40 5XIG-A nrPDB 160 9e-40 5XIP-A nrPDB 160 9e-40 5XIL-A nrPDB 156 2e-38 1H4S-A nrPDB 155 4e-38 1SER-A nrPDB 119 3e-27 2DQ3-A nrPDB 107 8e-24 3LSS-A nrPDB 91 1e-18 6OTE-A nrPDB 88 8e-18 4RQF-A nrPDB 88 9e-18 6GIR-A nrPDB 87 2e-17 3QO8-A nrPDB 85 5e-17 6BLJ-A nrPDB 81 1e-15 1WLE-A nrPDB 68 9e-12 2CIM-A nrPDB 67 1e-11 5Z5E-A nrPDB 62 4e-10 3W3S-A nrPDB 60 2e-09 1B76-A nrPDB 53 4e-07 1TKG-A nrPDB 52 5e-07 1ATI-A nrPDB 52 5e-07 3VQX-A nrPDB 49 4e-06 2PME-A nrPDB 48 9e-06 6JP2-A nrPDB 45 6e-05 1QE0-A nrPDB 44 9e-05 4E51-A nrPDB 44 1e-04 2ZNJ-A nrPDB 44 2e-04 1ADJ-A nrPDB 41 0.001 5XIX-A nrPDB 34 0.096 4UJ3-B nrPDB 34 0.13 3NET-A nrPDB 34 0.17 2OC2-A nrPDB 33 0.27 4AH6-A nrPDB 33 0.28 3NEM-A nrPDB 32 0.73 4WJ3-M nrPDB 31 1.0 2DU7-A nrPDB 31 1.2 5SWI-B nrPDB 31 1.3 1EFW-A nrPDB 31 1.4 3RWL-A nrPDB 31 1.5 4BGV-A nrPDB 30 2.0 2PVQ-A nrPDB 30 2.6 2ODR-C nrPDB 30 2.7 5MLQ-A nrPDB 29 3.5 5JNF-C nrPDB 29 3.5 5ES6-A nrPDB 29 3.5 5ES8-A nrPDB 29 3.8 5Y7F-A nrPDB 29 5.9 5MPB-R nrPDB 29 6.3 2D1L-A nrPDB 28 8.2 5ZG8-A nrPDB 28 8.3 2XGT-A nrPDB 28 9.5 >4YYE-A nrPDB Length = 460 Score = 624 bits (1610), Expect = e-179, Method: Composition-based stats. Identities = 437/439 (99%), Positives = 437/439 (99%) Query: 24 RKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFK 83 ATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFK Sbjct: 22 ASATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFK 81 Query: 84 FGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKK 143 FGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKK Sbjct: 82 FGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKK 141 Query: 144 DRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLI 203 DRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLI Sbjct: 142 DRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLI 201 Query: 204 DIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLN 263 DIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLN Sbjct: 202 DIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLN 261 Query: 264 PGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATF 323 PGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATF Sbjct: 262 PGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATF 321 Query: 324 GSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDME 383 GSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDME Sbjct: 322 GSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDME 381 Query: 384 PVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFE 443 PVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFE Sbjct: 382 PVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFE 441 Query: 444 KLTMSQIWEKFIELEKNYK 462 KLTMSQIWEKFIELEKNYK Sbjct: 442 KLTMSQIWEKFIELEKNYK 460 >1QF6-A nrPDB Length = 642 Score = 574 bits (1479), Expect = e-164, Method: Composition-based stats. Identities = 166/463 (35%), Positives = 249/463 (53%), Gaps = 38/463 (8%) Query: 1 MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTSM-------VSQRQDLFMTDP 53 MK W N + Y T A K A +A + + ++ DL+ Sbjct: 199 MKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQE 258 Query: 54 LSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDM 113 +PG +F+ +G IF +L F++ + K ++ + EV P + + LWEK+GHW+NY D M Sbjct: 259 EAPGMVFWHNDGWTIFRELEVFVRSKLK-EYQYQEVKGPFMMDRVLWEKTGHWDNYKDAM 317 Query: 114 FKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 F TT E EY +KPMNCPGH IF + +SY +LPLR ++F HRNE SG+L GL Sbjct: 318 F---TTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLM 374 Query: 174 RLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPD 233 R+R F QDD HIFCT Q++ E+ ++L+ +Y+ F F K + STRP+ Sbjct: 375 RVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYS-TFGFEK--------IVVKLSTRPE 425 Query: 234 HFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQL 293 IG ++W+ AE L LEE+ P++ G+GAFYGPK++ + D L + Q T+QL Sbjct: 426 KRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQL 485 Query: 294 DFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVII 353 DF LP R + +DN K P+MIHRA GS+ERF+ +L + G +P WL P Q VI+ Sbjct: 486 DFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIM 545 Query: 354 PVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILK 413 + T Q + NEL L++ V D+RNE +G++I+ L+ Sbjct: 546 NI-----------TDSQSEYVNELTQ------KLSNAGIRVKADLRNEKIGFKIREHTLR 588 Query: 414 NYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIE 456 Y+++ GD+EV+ K +R R K + ++++ EK + Sbjct: 589 RVPYMLVCGDKEVESGKVAVRTRRG-KDLGSMDVNEVIEKLQQ 630 >4HWO-A nrPDB Length = 411 Score = 508 bits (1309), Expect = e-144, Method: Composition-based stats. Identities = 157/422 (37%), Positives = 237/422 (56%), Gaps = 31/422 (7%) Query: 35 PATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLI 94 A + ++ DL+ +PG +F+ +G IF +L F++ + K ++ + EV P + Sbjct: 1 MARDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLK-EYQYQEVKGPFM 59 Query: 95 YKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRF 154 + LWEK+GHW+NY D MF TT E EY +KPMNCPGH IF + +SY +LPLR Sbjct: 60 MDRVLWEKTGHWDNYKDAMF---TTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRM 116 Query: 155 SDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFV 214 ++F HRNE SG+L GL R+R F QDD HIFCT Q++ E+ ++L+ +Y+ F F Sbjct: 117 AEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYS-TFGFE 175 Query: 215 KGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKL 274 K + STRP+ IG ++W+ AE L LEE+ P++ G+GAFYGPK+ Sbjct: 176 K--------IVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKI 227 Query: 275 DIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI 334 + + D L + Q T+QLDF LP R + +DN K P+MIHRA GS+ERF+ +L Sbjct: 228 EFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILT 287 Query: 335 DSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNV 394 + G +P WL P Q VI+ + T Q + NEL L++ V Sbjct: 288 EEFAGFFPTWLAPVQVVIMNI-----------TDSQSEYVNELTQ------KLSNAGIRV 330 Query: 395 DLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKF 454 D+RNE +G++I+ L+ Y+++ GD+EV+ K +R R K + ++++ EK Sbjct: 331 KADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRG-KDLGSMDVNEVIEKL 389 Query: 455 IE 456 + Sbjct: 390 QQ 391 >4P3N-A nrPDB Length = 415 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 186/420 (44%), Positives = 271/420 (64%), Gaps = 34/420 (8%) Query: 42 VSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE 101 + + Q+L+ LSPGS FFLP GA I+N LIEF++ + + K GF EVVTP I+ LW Sbjct: 18 IGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYR-KRGFQEVVTPNIFNSRLWM 76 Query: 102 KSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLH 161 SGHW++Y+++MF E EKE + LKPMNCPGHCL+F + RS+ ELPLR +DF LH Sbjct: 77 TSGHWQHYSENMFSFEV---EKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLH 133 Query: 162 RNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAE 221 RNE SGAL+GLTR+R+F QDD HIFC Q++ EI L + VY+ +F F Sbjct: 134 RNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYS-VFGF-------- 184 Query: 222 SNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDH 281 ++ +N STRP+ F+GD++VW+ AE+ L+ L E G+ W+LN GDGAFYGPK+DI + D Sbjct: 185 -SFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDA 243 Query: 282 LRKTHQVATIQLDFQLPERFDLKFKDQD-NSYKRPIMIHRATFGSIERFMALLIDSNEGR 340 + + HQ ATIQLDFQLP RF+L + D + KRP+++HRA GS+ER +A+L ++ G+ Sbjct: 244 IGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGK 303 Query: 341 WPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIR- 399 WPFWL+P Q +++PV C +K+R + +D F D+D+ Sbjct: 304 WPFWLSPRQVMVVPVGP-------TCDEYAQKVRQQ----------FHDAKFMADIDLDP 346 Query: 400 NEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEK 459 + +I++A L Y+++++VG++E NIR RDN+ E+ T+S+ E+ +L++ Sbjct: 347 GCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGER-TISETIERLQQLKE 405 >1NYR-A nrPDB Length = 645 Score = 477 bits (1227), Expect = e-135, Method: Composition-based stats. Identities = 157/468 (33%), Positives = 239/468 (51%), Gaps = 40/468 (8%) Query: 1 MKIQLVRWHCSRNALWNRAFYSTRKATKNASSATPATMTS-------MVSQRQDLFMTDP 53 + W N + Y T K A + + + +LF Sbjct: 198 LSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQ 257 Query: 54 L-SPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADD 112 L G +LPNGA I + IE + ++ G++ V TP++ L++ SGHW++Y +D Sbjct: 258 LVGAGLPLWLPNGATI-RREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQED 316 Query: 113 MFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGL 172 MF D E E L+PMNCP H +I+ K SY ELP+R ++ +HR EASGA+SGL Sbjct: 317 MFPPMQLD-ETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGL 375 Query: 173 TRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTR- 231 R+R +D HIF P Q+K E + +I VY K F F +Y S R Sbjct: 376 QRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVY-KDFGF--------EDYSFRLSYRD 426 Query: 232 ---PDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQV 288 + + D +WN AE +LKE +E G ++ G+ AFYGPKLD+ V + K + Sbjct: 427 PEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETL 486 Query: 289 ATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPY 348 +T QLDF LPERFDL + QD + RP++IHR ++ERF+A L + +G +P WL P Sbjct: 487 STAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPK 546 Query: 349 QAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIK 408 Q IIPVN +D+ ++L++EL++ + V +D RNE +GY+I+ Sbjct: 547 QVQIIPVN------VDLHYDYARQLQDELKSQGV----------RVSIDDRNEKMGYKIR 590 Query: 409 SAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIE 456 A ++ Y I+VGD+EV+ + N+R+ + E + + ++ Sbjct: 591 EAQMQKIPYQIVVGDKEVENNQVNVRQY-GSQDQETVEKDEFIWNLVD 637 >3A31-A nrPDB Length = 471 Score = 298 bits (763), Expect = 3e-81, Method: Composition-based stats. Identities = 117/400 (29%), Positives = 190/400 (47%), Gaps = 35/400 (8%) Query: 55 SPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMF 114 G F G I L E + + + G+ V TP+I L++ SGH E Y ++M+ Sbjct: 38 GAGVPLFSLGGGPIRYALAE-VLAKFHARRGYYVVETPIIASTELFKVSGHIEFYRNNMY 96 Query: 115 KVETTDEEKEEYGLKPMNCPGHCLIF---GKKDRSYNELPLRFSDFSPLHRNEASGALSG 171 D E E+ +KPMNCP H L+F K RS LP + +F +HR E SG++ G Sbjct: 97 ---LFDIEGHEFAVKPMNCPYHILLFLNEVAKHRSKLPLPFKVFEFGRVHRYEPSGSIYG 153 Query: 172 LTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTR 231 L R+R F QDD HI +V +++ + + +V ++F G S ++ S + Sbjct: 154 LLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKL--GVSSETFKVRLSMSDK 211 Query: 232 P---DHFIGDLKVWNHAEQVLKEILEESGKPWKLN----PGDGAFYGPKLDIMVTDH--- 281 F+G + W AE+ L+E + + ++ G+ AFYGPKLD ++ Sbjct: 212 SLIGKEFMGSKEEWEGAEEALREAASRINEKYGIDIVELEGEAAFYGPKLDFIMMVEESG 271 Query: 282 LRKTHQVATIQLDFQLPERFDL-KFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGR 340 + K Q+ TIQ DF LP RF L ++ + +IHRA GSIERF+ + ++ GR Sbjct: 272 VSKEWQMGTIQFDFNLPRRFRLYDVVREEFGIEEVYIIHRALLGSIERFLGVYLEHRRGR 331 Query: 341 WPFWLNPYQAVIIPVNTK---NVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLD 397 PF L P Q +I V T + + D+ +++ K L ++ + D Sbjct: 332 MPFTLAPIQFAVIAVKTGGEVDREIEDLASSIAKGLLDK----GFRVAVKGSSKTGLSSD 387 Query: 398 IRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERD 437 +R+ I+S + + +G +EV+ + ++R D Sbjct: 388 VRH------IESTAKPAVN--VFIGAKEVREKVLDVRVFD 419 >3IAL-A nrPDB Length = 518 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 85/419 (20%), Positives = 163/419 (38%), Gaps = 67/419 (15%) Query: 57 GSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWE-KSGHWENYADDMFK 115 G + F P G + N ++ + ++ K G ++++ P + ++ + +S H + + + F Sbjct: 46 GCVVFRPYGFFMENAIMRLCE-EEYAKVGISQILFPTVIPESFLKKESDHIKGFEAECFW 104 Query: 116 VETTDEE--KEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 VE + +E L+P + +F K RSY +LPL+ + R+E L Sbjct: 105 VEKGGLQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKN-TKPLI 163 Query: 174 RLRKFHQDDGHIFC-TPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRP 232 R+R+ H ++ H T S++ + K+ID +++ F Sbjct: 164 RVREIHWNEAHCCHATAEDAVSQLSDYWKVIDTIFSDELCFKG----------------- 206 Query: 233 DHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQ 292 Q L+ + W PG A Y D+++ + Q A I Sbjct: 207 --------------QKLRRVC------WDRFPG--ADYSEVSDVVMP--CGRVLQTAGIH 242 Query: 293 -LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPFWLNP 347 L + FD+ + ++ N P + G R +A + DS P + P Sbjct: 243 NLGQRFSSTFDILYANKANESVHPYL---TCAGISTRVLACALSIHGDSGGLVLPPLIAP 299 Query: 348 YQAVIIPVNT--KNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIR-NEPVG 404 VIIP+ KN Q+ D Q+ L E D L V +D ++ +G Sbjct: 300 IHVVIIPIGCGKKNNQESD-----QQVLGKVNEIADTLKSKL---GLRVSIDDDFSKSMG 351 Query: 405 YRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEK-LTMSQIWEKFIELEKNYK 462 ++ LK I VG ++ + + RD K ++ + ++++ + +N++ Sbjct: 352 DKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDVGKDQKRVIPITEVMKVSSHTTENHE 410 >6NAB-A nrPDB Length = 513 Score = 199 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 82/405 (20%), Positives = 155/405 (38%), Gaps = 75/405 (18%) Query: 56 PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTP-LIYKKTLWEKSGHWENYADDMF 114 G F PN ++ + +F + K K G V+ P + K+ L + H E ++ ++ Sbjct: 42 SGCYIFRPNCWFVWESVQKFFDAEIK-KLGVQNVMFPLFVTKRALETEKDHVEGFSPEVA 100 Query: 115 KVETTDEE--KEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGL 172 V + +E L+P + + K +S+ +LPL+ + ++ + R E A+ Sbjct: 101 WVTKSGNSDLQEPIALRPTSETIMYPSYAKWIQSHRDLPLKLNQWTNVVRWEFKHAVP-F 159 Query: 173 TRLRKFHQDDGHI-FCTPSQVKSEIFNSLKLIDIVYNKIFPF-VKGGSGAESNYF--INF 228 R R+F+ +GH F + + E+F L+L VY ++ V G+ E+ F ++ Sbjct: 160 IRSREFYWQEGHSAFKSKEEADEEVFTILELYKRVYEELLAVPVIKGTKTENEKFAGADY 219 Query: 229 STRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQV 288 +T + FI + Q Sbjct: 220 TTTVETFIATN-------------------------------------------GRAVQG 236 Query: 289 ATI-QLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPF 343 T L + F ++F+ ++ + + ++G R + ++I D P Sbjct: 237 GTSHHLGQNFSKMFKIQFEAENKETQFAY---QNSWGLSTRTLGVMIMVHGDDKGMVLPP 293 Query: 344 WLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPV 403 + Q V+IP+ K+ + K++ NELE V LD R E Sbjct: 294 RVAFCQVVVIPLIFKDKDNATLV-EKTKEIYNELEK----------AGIRVKLDDRLERT 342 Query: 404 -GYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTM 447 G++ L+ I VG ++++ Q+ + RD + EK TM Sbjct: 343 PGWKYNYWELRGVPLRIEVGPKDLEKQQIMLCRRD---TGEKWTM 384 >2I4O-A nrPDB Length = 458 Score = 181 bits (459), Expect = 5e-46, Method: Composition-based stats. Identities = 71/432 (16%), Positives = 145/432 (33%), Gaps = 52/432 (12%) Query: 50 MTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENY 109 M + G +LP G ++ K+ + ++ +Q + G E++ P + LW +SG ++ Y Sbjct: 51 MLRQEAAGIYAWLPLGHRVLKKIEQIVREEQ-NRAGAIELLMPTLQLADLWRESGRYDAY 109 Query: 110 ADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGAL 169 +M ++ D K E P N IF +SY LPL R+E Sbjct: 110 GPEMLRIA--DRHKRELLYGPTNEEMITEIFRAYIKSYKSLPLNLYHIQWKFRDEQRPRF 167 Query: 170 SGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFP-FVKGGSGAESNYFINF 228 G+ R R+F D + F + +N + + Y + F + Sbjct: 168 -GVMRGREFLMKDAYSFDVDEAGARKSYNKMFV---AYLRTFARMGLKAIPMRAETGPIG 223 Query: 229 STRPDHFIGDLKVWNHAEQVLKEILE----ESGKPWKLNPGD-----GAFYGPKLDIMVT 279 FI + + +++L + + + + Y D+ Sbjct: 224 GDLSHEFIVLAETGESGVYIDRDVLNLPVPDENVDYDGDLTPIIKQWTSVYAATEDVHEP 283 Query: 280 DHLRKT------HQVATIQLDFQL------PERFDLKFKDQDNSYKRPIMIHRATFGS-I 326 I++ + D + IH ++G + Sbjct: 284 ARYESEVPEANRLNTRGIEVGQIFYFGTKYSDSMKANVTGPDGTDAP---IHGGSYGVGV 340 Query: 327 ERFMALLID----SNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDM 382 R + +I+ N WP + P++ I+ + + C L ++L Sbjct: 341 SRLLGAIIEACHDDNGIIWPEAVAPFRVTILNLKQGDAATDAACDQLYREL--------- 391 Query: 383 EPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSF 442 + +V D ++ G + +A L + I VG + K ++ R + + Sbjct: 392 -----SAKGVDVLYDDTDQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELK-RRSDGAR 445 Query: 443 EKLTMSQIWEKF 454 E L ++ + + Sbjct: 446 ENLALADVVARL 457 >5UCM-A nrPDB Length = 579 Score = 171 bits (434), Expect = 5e-43, Method: Composition-based stats. Identities = 39/162 (24%), Positives = 73/162 (45%), Gaps = 7/162 (4%) Query: 50 MTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENY 109 M L+ G +LP G ++ K+ ++ ++ G EV+ P + LW++SG WE Y Sbjct: 39 MIRRLASGLYTWLPMGLRVLRKVETIVR-EEMNAAGALEVLMPAVQPAELWQESGRWEQY 97 Query: 110 ADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGAL 169 ++ +++ D + E+ + P + + + SY +LP+ F R+E Sbjct: 98 GPELLRLK--DRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRF 155 Query: 170 SGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIF 211 GL R R+F D + F + ++ + Y+KIF Sbjct: 156 -GLMRGREFIMKDAYSFHLSQDSLQQTYDGMYQ---AYSKIF 193 Score = 55.2 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 59/157 (37%), Gaps = 24/157 (15%) Query: 292 QLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGS-IERFMALLID----SNEGRWPFWLN 346 QL + E L + +P+ + +G + R +A I+ WP L Sbjct: 422 QLGTKYSEAMKLSVLSEQG---KPVNLIMGCYGIGVSRVVAAAIEQNHDERGILWPSALA 478 Query: 347 PYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPV--G 404 P+Q ++P+ + T K+ ++L A+ L F V LD R++ G Sbjct: 479 PFQIALVPLKYE--------TESVKQATDKLYAE------LTAAGFEVLLDDRDKKTSPG 524 Query: 405 YRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKS 441 + L + I++ D + + R + +S Sbjct: 525 VKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSES 561 >1NJ2-A nrPDB Length = 501 Score = 168 bits (424), Expect = 6e-42, Method: Composition-based stats. Identities = 81/414 (19%), Positives = 159/414 (38%), Gaps = 71/414 (17%) Query: 57 GSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKT-LWEKSGHWENYADDMFK 115 G ++P+G I ++ ++ + EV+ PL+ + L +++ H + + D+++ Sbjct: 62 GMHVWMPHGFMIRKNTLKILR--RILDRDHEEVLFPLLVPEDELAKEAIHVKGFEDEVYW 119 Query: 116 VETTDEEK--EEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 V K + L+P + +F RS+ +LP+RF R E L Sbjct: 120 VTHGGLSKLQRKLALRPTSETVMYPMFALWVRSHTDLPMRFYQVVNTFRYETKH-TRPLI 178 Query: 174 RLRKFHQ-DDGHIFC-TPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTR 231 R+R+ + H T S+ + ++ ++++ +N + + R Sbjct: 179 RVREITTFKEAHTIHATASEAEEQVERAVEIYKEFFNSL------------GIPYLITRR 226 Query: 232 PDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATI 291 P PW PG + Y D ++ D KT Q+ T+ Sbjct: 227 P--------------------------PWDKFPG--SEYTVAFDTLMPD--GKTLQIGTV 256 Query: 292 Q-LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPFWLN 346 L F++KF+ + ++ +H+ +G +R +A +I D + P + Sbjct: 257 HNLGQTFARTFEIKFETPEGDHEY---VHQTCYGLSDRVIASVIAIHGDESGLCLPPDVA 313 Query: 347 PYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYR 406 +Q VI+P+ K + M ++LR+ LEA F V LD R+ G + Sbjct: 314 AHQVVIVPIIFKKAAEEVM--EACRELRSRLEA----------AGFRVHLDDRDIRAGRK 361 Query: 407 IKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKN 460 ++ + +G +++ I RD + + I E EL K+ Sbjct: 362 YYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKV-TADLQGIEETLRELMKD 414 >4K87-A nrPDB Length = 535 Score = 167 bits (422), Expect = 1e-41, Method: Composition-based stats. Identities = 75/420 (17%), Positives = 147/420 (35%), Gaps = 71/420 (16%) Query: 56 PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTP-LIYKKTLWEKSGHWENYADDMF 114 G P I+ + +F + K K G P + + L ++ H ++A ++ Sbjct: 67 SGCYILRPWAYAIWEAIKDFFDAEIK-KLGVENCYFPMFVSQSALEKEKTHVADFAPEVA 125 Query: 115 KVETTDEEK--EEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGL 172 V + + + E ++P + + K +S+ +LP++ + + + R E Sbjct: 126 WVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPF 184 Query: 173 TRLRKFHQDDGHI-FCTPSQVKSEIFNSLKLIDIVYNKIFPF-VKGGSGAESNYFI--NF 228 R R+F +GH F T + E+ L L VY ++ V G E F ++ Sbjct: 185 LRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDY 244 Query: 229 STRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQV 288 +T + FI + Q Sbjct: 245 TTTIEAFI-------------------------------------------SASGRAIQG 261 Query: 289 ATI-QLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPF 343 T L + F++ F+D ++ ++ ++G R + ++ D+ P Sbjct: 262 GTSHHLGQNFSKMFEIVFEDPKIPGEKQF-AYQNSWGLTTRTIGVMTMVHGDNMGLVLPP 320 Query: 344 WLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIR-NEP 402 + Q VIIP N + AL K + L + V D+R N Sbjct: 321 RVACVQVVIIPCGITNALSEEDKEALIAKCND-------YRRRLLSVNIRVRADLRDNYS 373 Query: 403 VGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTM--SQIWEKFIELEKN 460 G++ LK + VG +++ ++ RD + EKLT+ ++ K + ++ Sbjct: 374 PGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRD---TGEKLTVAENEAETKLQAILED 430 >1NJ8-A nrPDB Length = 459 Score = 165 bits (418), Expect = 3e-41, Method: Composition-based stats. Identities = 83/435 (19%), Positives = 162/435 (37%), Gaps = 71/435 (16%) Query: 40 SMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTL 99 S + ++ +++ G +LP G KI E ++ + G +E + P++ + L Sbjct: 12 SDILEKAEIYDVRYPIKGCGVYLPYGFKIRRYTFEIIR-NLLDESGHDEALFPMLIPEDL 70 Query: 100 W-EKSGHWENYADDMFKVETTDEEKEE--YGLKPMNCPGHCLIFGKKDRSYNELPLRFSD 156 +++ H + + D+++ V + + + L+P + + + + +LP++ Sbjct: 71 LAKEAEHIKGFEDEVYWVTHGGKTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQ 130 Query: 157 FSPLHRNEASGALSGLTRLRK-FHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVK 215 R E L RLR+ + H T K E N +K +Y K F Sbjct: 131 IVNTFRYETKH-TRPLIRLREIMTFKEAH---TAHSTKEEAENQVKEAISIYKKFF---- 182 Query: 216 GGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLD 275 S RP+ W PG A Y D Sbjct: 183 ----DTLGIPYLISKRPE--------------------------WDKFPG--AEYTMAFD 210 Query: 276 IMVTDHLRKTHQVATIQ-LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI 334 + D +T Q+AT+ L + F++ F+ + +G +R +A +I Sbjct: 211 TIFPD--GRTMQIATVHNLGQNFSKTFEIIFETPTGDKDYAY---QTCYGISDRVIASII 265 Query: 335 ----DSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDW 390 D P + P Q VI+P+ K + D+ K++ +L+ Sbjct: 266 AIHGDEKGLILPPIVAPIQVVIVPLIFKGKE--DIVMEKAKEIYEKLK-----------G 312 Query: 391 HFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFE--KLTMS 448 F V +D R+ G + +K I VG ++++ +K + RD + F+ + + Sbjct: 313 KFRVHIDDRDIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKFQVDETQLM 372 Query: 449 QIWEK-FIELEKNYK 462 ++ EK + +N K Sbjct: 373 EVVEKTLNNIMENIK 387 >4NCX-A nrPDB Length = 506 Score = 162 bits (409), Expect = 4e-40, Method: Composition-based stats. Identities = 78/420 (18%), Positives = 144/420 (34%), Gaps = 72/420 (17%) Query: 56 PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTP-LIYKKTLWEKSGHWENYADDMF 114 G P I+ + F + K K P + K L ++ H E ++ ++ Sbjct: 42 SGCYILRPAAYYIWECVQAFFNKEIK-KLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVA 100 Query: 115 KVETTDEEK--EEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGL 172 V + EE ++P + +F K RSY +LPL+ + ++ + R E Sbjct: 101 WVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTP-F 159 Query: 173 TRLRKFHQDDGHIFCT-PSQVKSEIFNSLKLIDIVYNKIFPF-VKGGSGAESNYF--INF 228 R R+F +GH + +F+ L L Y + + G +E F NF Sbjct: 160 IRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANF 219 Query: 229 STRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQV 288 ++ + FI + + Q Sbjct: 220 TSTAEAFISEN-------------------------------------------GRAIQA 236 Query: 289 ATIQ-LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPF 343 AT L + F ++F ++ + +H+ ++G R + ++I D P Sbjct: 237 ATSHYLGTNFAKMFKIEF---EDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPP 293 Query: 344 WLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE-P 402 ++ Y+ VI+P+ K + + + K + L+ + N D R Sbjct: 294 NVSKYKVVIVPIFYKTTDENAIHS-YCKDIEKILK----------NAQINCVYDDRASYS 342 Query: 403 VGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK 462 GY+ L+ I VG +++Q I RDN + S + E L +K Sbjct: 343 PGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHK 402 >5F9Y-A nrPDB Length = 511 Score = 161 bits (406), Expect = 7e-40, Method: Composition-based stats. Identities = 74/420 (17%), Positives = 148/420 (35%), Gaps = 73/420 (17%) Query: 56 PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTP-LIYKKTLWEKSGHWENYADDMF 114 G P I+ + + K + P + +K L + H E ++ ++ Sbjct: 46 SGCYILRPWSYFIWETIQSVFDQKIK-QHDVQNAYFPIFVTQKKLETEKDHVEGFSPEVA 104 Query: 115 KVETTDEEK--EEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGL 172 V + + E ++P + F K RS+ +LPL+ + ++ + R E Sbjct: 105 WVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTP-F 163 Query: 173 TRLRKFHQDDGHIFC-TPSQVKSEIFNSLKLIDIVYNKIFPF-VKGGSGAESNYFINFST 230 R R+F +GH T + + L +Y + V G+ +E+ F Sbjct: 164 IRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKF----- 218 Query: 231 RPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVAT 290 G ++ + + + + Q AT Sbjct: 219 -----------------------------------PGGDITKSIEGFIPE-IGRAVQAAT 242 Query: 291 IQ-LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPFWL 345 L + F ++F+D+ + + H+ ++G R + ++I D+ P + Sbjct: 243 SHLLGQNFSKMFGVEFEDEKGNKEY---AHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKV 299 Query: 346 NPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIR-NEPVG 404 P Q V + + T QKK+ NE+E L V +D R N G Sbjct: 300 APVQ-----VIIIPIIFKTVITEEQKKICNEVE------CILKKAGVRVKIDDRSNYTPG 348 Query: 405 YRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLT--MSQIWEKFIELEKNYK 462 ++ +K VG +++ + + RDN EK+ +S++ K +L + ++ Sbjct: 349 WKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDN---MEKMDIPISELESKIPKLLEEFQ 405 >6MN8-A nrPDB Length = 505 Score = 161 bits (406), Expect = 8e-40, Method: Composition-based stats. Identities = 78/432 (18%), Positives = 149/432 (34%), Gaps = 72/432 (16%) Query: 27 TKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGF 86 +N S +T + + + G P I+ + E+ + K K G Sbjct: 14 DENYSEWYVQVITKA--EMIEYYDIS----GCYVLRPWSYAIWEFIQEWFDEEIK-KLGV 66 Query: 87 NEVVTPLIYKKT-LWEKSGHWENYADDMFKVETTDEEK--EEYGLKPMNCPGHCLIFGKK 143 PL ++ L ++ H ++A ++ + + E ++P + + K Sbjct: 67 KNCYFPLFVSQSALEKEKTHISDFAPEVAWITRAGQSDLAEAIAIRPTSETVMYPSYAKW 126 Query: 144 DRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGH-IFCTPSQVKSEIFNSLKL 202 +S+ +LP++ + + + R E R R+F +GH F + + + E+F L L Sbjct: 127 VQSHRDLPIKLNQWCNVVRWEFKHPTP-FLRTREFLWQEGHTAFQSKDEAEDEVFKILDL 185 Query: 203 IDIVYNKIFPF-VKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWK 261 +Y + V G E F Sbjct: 186 YAQIYIDLLAIPVIKGRKTEKENFA----------------------------------- 210 Query: 262 LNPGDGAFYGPKLDIMVTDHLRKTHQVATI-QLDFQLPERFDLKFKDQDNSYKRPIMIHR 320 G + ++ V + + Q AT L + F++ F+D + K I + Sbjct: 211 -----GGDFTATVEAYVPVN-GRGIQGATSHHLGQNFSKMFNISFEDPNGGGK--IYAWQ 262 Query: 321 ATFGSIERFMALLI----DSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNE 376 ++G R + L+ D+ P + Q +I+PV + + TAL Sbjct: 263 NSWGISTRTIGALVMIHGDNCGLVLPPRVATIQMIIVPVGINAQTKDEQKTAL------- 315 Query: 377 LEADDMEPVPLNDWHFNVDLDIRNE-PVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRE 435 +E L D +LDIR+ G++ LK I +G +++ + Sbjct: 316 IEKAKEINNKLMDASIRAELDIRDHISPGWKFNHWELKGVPVRIEIGPKDLANNQVTCVI 375 Query: 436 RDNRKSFEKLTM 447 R S EK T+ Sbjct: 376 R---YSGEKRTI 384 >5XIG-A nrPDB Length = 500 Score = 160 bits (405), Expect = 9e-40, Method: Composition-based stats. Identities = 77/450 (17%), Positives = 158/450 (35%), Gaps = 79/450 (17%) Query: 23 TRKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKF 82 T K +N S + S+ + + G P I+ K+ F + K Sbjct: 5 TAKKDENFSEWYTQAIVR--SEMIEYYDIS----GCYIMRPWAFHIWEKVQRFFDDEIK- 57 Query: 83 KFGFNEVVTP-LIYKKTLWEKSGHWENYADDMFKVETTDEEK--EEYGLKPMNCPGHCLI 139 K G P + + L ++ H E ++ ++ V + E+ ++P + Sbjct: 58 KMGVENSYFPMFVSRHKLEKEKDHVEGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPA 117 Query: 140 FGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFC-TPSQVKSEIFN 198 + K RS+ +LPL+ + + + R E R R+F +GH T + + + Sbjct: 118 YAKWIRSHRDLPLKLNQWCSVVRWEFKQPTP-FLRTREFLWQEGHTAHATEEEAWELVLD 176 Query: 199 SLKLIDIVYNKIFPF-VKGGSGAESNYFI--NFSTRPDHFIGDLKVWNHAEQVLKEILEE 255 L+L Y + V G +E F +T + FI + Sbjct: 177 ILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPEN---------------- 220 Query: 256 SGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQ-LDFQLPERFDLKFKDQDNSYKR 314 + Q AT L + F+++F+D++ + Sbjct: 221 ---------------------------GRGIQAATSHLLGTNFAKMFEIEFEDEEGHKR- 252 Query: 315 PIMIHRATFGSIERFMALLI----DSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQ 370 ++H+ ++G R + ++I D P + Q VIIP+ K+ ++ Sbjct: 253 --LVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEI----- 305 Query: 371 KKLRNELEADDMEPVPLNDWHFNVDLDIR-NEPVGYRIKSAILKNYSYLIIVGDEEVQLQ 429 L L V +D R N G++ +K + +G +++ Sbjct: 306 ------LGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKG 359 Query: 430 KYNIRERDNRKSFEKLTMSQIWEKFIELEK 459 + RD ++++ ++ + + K +EL + Sbjct: 360 TARVVRRDTGEAYQ-ISWADLAPKLLELME 388 >5XIP-A nrPDB Length = 498 Score = 160 bits (405), Expect = 9e-40, Method: Composition-based stats. Identities = 73/428 (17%), Positives = 147/428 (34%), Gaps = 78/428 (18%) Query: 23 TRKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKF 82 T K + N + + + + + G P +I+ + +F K Sbjct: 6 TAKKSTNFADWYTQVIVR--GELVEYYDIS----GCYIIRPWAYRIWEAVQKFFDDGIK- 58 Query: 83 KFGFNEVVTP-LIYKKTLWEKSGHWENYADDMFKVETTDEEK--EEYGLKPMNCPGHCLI 139 + G P + + L ++ H E + ++ V + + E+ ++P + Sbjct: 59 RLGVENCYFPMFVSQAKLEKEKDHVEGFKPEVAWVTHYGDSELPEKVAIRPTSETIMYPA 118 Query: 140 FGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFC-TPSQVKSEIFN 198 + K RS+ +LPL+ + ++ + R E R R+F +GH T + + + Sbjct: 119 YAKWIRSHRDLPLKLNQWNNVVRWEFKQPTP-FLRTREFLWQEGHTAHATEEEAYTLVLE 177 Query: 199 SLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGK 258 L+L Y N + F G K Sbjct: 178 ILELYRQWYEDYLAVPVIKGEKSEN---------EKFAGGKKT----------------- 211 Query: 259 PWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQ-LDFQLPERFDLKFKDQDNSYKRPIM 317 ++ ++ D + Q AT L F ++F+D+ + + + Sbjct: 212 -------------TTIEGIIPDT-GRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQ---L 254 Query: 318 IHRATFGSIERFMALLI----DSNEGRWPFWLNPYQAVIIPV---NTKNVQQLDMCTALQ 370 +H+ ++G R + ++I D P + QAVIIP+ T ++ + C L+ Sbjct: 255 VHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFKETGGMEIVAKCRELE 314 Query: 371 KKLRNELEADDMEPVPLNDWHFNVDLDIR-NEPVGYRIKSAILKNYSYLIIVGDEEVQLQ 429 + LN V +D R N G++ LK + +G +V+ Sbjct: 315 R--------------LLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESC 360 Query: 430 KYNIRERD 437 + + RD Sbjct: 361 QTRVVRRD 368 >2J3M-A nrPDB Length = 572 Score = 159 bits (403), Expect = 2e-39, Method: Composition-based stats. Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 7/162 (4%) Query: 50 MTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENY 109 ++ G +LP ++ KL M+ ++ K E++ P + LW++SG +E Y Sbjct: 31 YIRQVAAGIYSYLPLANRVLEKLKTIMR-EEFEKIDAVEMLMPALLPAELWKESGRYETY 89 Query: 110 ADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGAL 169 ++++++ D +Y L P + + + SY LPL +R+E Sbjct: 90 GPNLYRLK--DRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSR- 146 Query: 170 SGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIF 211 SGL R R+F DG+ F + + + + Y++IF Sbjct: 147 SGLLRGREFIMKDGYSFHADEASLDQSY---RDYEKAYSRIF 185 Score = 54.1 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 60/157 (38%), Gaps = 23/157 (14%) Query: 292 QLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGS-IERFMALLID----SNEGRWPFWLN 346 +L + + D++ K IM +G + R ++ +++ WP + Sbjct: 413 KLGTRYSDAMGATVLDENGREKSVIM---GCYGIGVSRLLSAIVEQNADERGINWPTGIA 469 Query: 347 PYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYR 406 P+ ++ +N K+ Q KL E+EA + + + V +D RNE G + Sbjct: 470 PFDLHVVQMNVKD--------EYQTKLSQEVEAM------MTEAGYEVLVDDRNERAGVK 515 Query: 407 IKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFE 443 A L I VG + V ++ + + E Sbjct: 516 FADADLIGCPIRITVGKKAVD-GVVEVKIKRTGEMLE 551 >6H9X-A nrPDB Length = 430 Score = 157 bits (397), Expect = 8e-39, Method: Composition-based stats. Identities = 52/241 (21%), Positives = 91/241 (37%), Gaps = 29/241 (12%) Query: 37 TMTSMVSQRQDLFMTDPLSPGSMFFLPNG--AKIFNKLIEFMKLQQKFKFGFNEVVTPLI 94 T+ M D L+ GS F + G A++ L +FM + G++E P + Sbjct: 141 TLGEMHGG-LDFAAAVKLT-GSRFVVMKGQLARLHRALAQFMLDLHTEQHGYSENYVPYL 198 Query: 95 YKKTLWEKSGHWENYADDMFKVETTDEEKEE--YGLKPMNCPGHCLIFGKKDRSYNELPL 152 + +G +A D+F +EE + Y L P + + ++LP+ Sbjct: 199 VNQDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDDLPI 258 Query: 153 RFSDFSPLHRNEASG---ALSGLTRLRKFHQDDGHIFCTP-------SQVKSEIFNSLKL 202 + + +P R+EA GL R+ +F + + P ++ L+L Sbjct: 259 KMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQL 318 Query: 203 IDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKL 262 + + Y K+ G G FS + DL+VW A+ +EI S W Sbjct: 319 LGLPYRKV-ALCTGDMG--------FSACKTY---DLEVWVPAQNTYREISSCSNV-WDF 365 Query: 263 N 263 Sbjct: 366 Q 366 >5XIL-A nrPDB Length = 512 Score = 156 bits (394), Expect = 2e-38, Method: Composition-based stats. Identities = 71/395 (17%), Positives = 143/395 (36%), Gaps = 68/395 (17%) Query: 56 PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKT-LWEKSGHWENYADDMF 114 G P ++ + F+ + K G + P+ ++ L + H E +A ++ Sbjct: 33 SGCYIIRPWAYYVWKCVQRFLGGKI-EKLGVEDCYFPMFVSRSCLEREKDHIEGFAPEVA 91 Query: 115 KVETTD--EEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGL 172 V E ++ ++P + + K RS+ +LP+R + ++ + R E S Sbjct: 92 WVTRAGDTELEQPVAVRPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEFSHPTP-F 150 Query: 173 TRLRKFHQDDGHI-FCTPSQVKSEIFNSLKLIDIVYNKIFPF-VKGGSGAESNYFI--NF 228 R R+F +GH + + E+ L+ VY ++ V G E F ++ Sbjct: 151 IRTREFLWQEGHCAWAKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDY 210 Query: 229 STRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQV 288 +T + FI + + + Q Sbjct: 211 TTTVETFI-------------------------------------------EAVGRGCQG 227 Query: 289 ATIQ-LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPF 343 AT L + FD++F+D +N+ ++ ++ + ++G R + ++I D+ P Sbjct: 228 ATSHNLGQNFGKMFDIRFQDPENN-EQTLIPWQNSWGLSTRVIGVMIMVHGDNRGMVMPP 286 Query: 344 WLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDME-PVPLNDWHFNVDLDIR-NE 401 + Q +IIPV + ++ R EL A L + D+R N Sbjct: 287 RVASTQVIIIPVG--------ITKDTTEEARQELLASCWRLESELCEGGVRARCDLRDNY 338 Query: 402 PVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRER 436 G+R +K + +G E+ + + R Sbjct: 339 SPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVR 373 >1H4S-A nrPDB Length = 477 Score = 155 bits (391), Expect = 4e-38, Method: Composition-based stats. Identities = 73/394 (18%), Positives = 137/394 (34%), Gaps = 67/394 (17%) Query: 57 GSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYK-KTLWEKSGHWENYADDMFK 115 G++ P G I+ + + + + + G PL L +++ H E ++ ++ Sbjct: 35 GTIVVRPYGYAIWENIQQ-VLDRMFKETGHQNAYFPLFIPMSFLRKEAEHVEGFSPELAV 93 Query: 116 VETTDEEK--EEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLT 173 V E+ E ++P + ++ K RS+ +LP + + + R E Sbjct: 94 VTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMR--TRPFL 151 Query: 174 RLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPD 233 R +F +GH + E + I + + + G T + Sbjct: 152 RTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEG--------LKTEKE 203 Query: 234 HFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQ- 292 F GA Y ++ ++ D K Q T Sbjct: 204 KF------------------------------AGAVYTTTIEALMKD--GKALQAGTSHY 231 Query: 293 LDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLI----DSNEGRWPFWLNPY 348 L FD+KF+D+D K +H ++G RF+ +I D P L P Sbjct: 232 LGENFARAFDIKFQDRDLQVKY---VHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPI 288 Query: 349 QAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNE-PVGYRI 407 Q VI+P+ ++ + + LR L A V LD R++ GY+ Sbjct: 289 QVVIVPIYKDESRERVL--EAAQGLRQALLAQ----------GLRVHLDDRDQHTPGYKF 336 Query: 408 KSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKS 441 LK + + +G ++++ + + R K Sbjct: 337 HEWELKGVPFRVELGPKDLEGGQAVLASRLGGKE 370 >2ZR2-A nrPDB Length = 455 Score = 145 bits (365), Expect = 4e-35, Method: Composition-based stats. Identities = 42/221 (19%), Positives = 83/221 (37%), Gaps = 27/221 (12%) Query: 47 DLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHW 106 D +S ++L N I + + L + + GF V+ P + ++ + E S + Sbjct: 173 DFARAAKVSGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSF 232 Query: 107 ENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEAS 166 E++ D ++KVE D P+ I +LPL + SP R EA Sbjct: 233 EDFEDVIYKVEDEDLYLIPTAEHPLAGMHANEILDG-----KDLPLLYVGVSPCFRKEAG 287 Query: 167 GA---LSGLTRLRKFHQDDGHIFCTPSQ-------VKSEIFNSLKLIDIVYNKIFPFVKG 216 A G+ R+ +FH+ + ++ P + + + ++I Y ++ G Sbjct: 288 TAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPY-RVVNICTG 346 Query: 217 GSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESG 257 G + D++ W + +E++ S Sbjct: 347 DLGYVAAKKY-----------DIEAWMPGQGKFREVVSASN 376 >3ERR-A nrPDB Length = 536 Score = 121 bits (303), Expect = 7e-28, Method: Composition-based stats. Identities = 40/251 (15%), Positives = 87/251 (34%), Gaps = 26/251 (10%) Query: 50 MTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENY 109 +S + L ++ + + + GF + P ++ + +GH+ Y Sbjct: 258 RISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAY 317 Query: 110 ADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASG-- 167 D ++ + TD L + + Y LPLR++ ++P R+EA Sbjct: 318 RDQVWAIAETDLY-----LTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFG 372 Query: 168 -ALSGLTRLRKFHQDDGHIFCTP---------SQVKSEIFNSLKLIDIVYNKIFPFVKGG 217 + GL R+ +FH+ + ++ ++ L+L+++ Y ++ G Sbjct: 373 KDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPY-RLVEVATGD 431 Query: 218 SGAESNYFINFS--------TRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAF 269 G ++ R H L W L+ E + + A Sbjct: 432 MGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTAL 491 Query: 270 YGPKLDIMVTD 280 P++ M+ + Sbjct: 492 ATPRILAMLLE 502 >1SER-A nrPDB Length = 421 Score = 119 bits (298), Expect = 3e-27, Method: Composition-based stats. Identities = 40/251 (15%), Positives = 87/251 (34%), Gaps = 26/251 (10%) Query: 50 MTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENY 109 +S + L ++ + + + GF + P ++ + +GH+ Y Sbjct: 149 RISQVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAY 208 Query: 110 ADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASG-- 167 D ++ + TD L + + Y LPLR++ ++P R+EA Sbjct: 209 RDQVWAIAETDLY-----LTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSFG 263 Query: 168 -ALSGLTRLRKFHQDDGHIFCTP---------SQVKSEIFNSLKLIDIVYNKIFPFVKGG 217 + GL R+ +FH+ + ++ ++ L+L+++ Y ++ G Sbjct: 264 KDVRGLMRVHQFHKVEQYVLTEASLEASDRAFQELLENAEEILRLLELPY-RLVEVATGD 322 Query: 218 SGAESNYFINFS--------TRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAF 269 G ++ R H L W L+ E + + A Sbjct: 323 MGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLNNTAL 382 Query: 270 YGPKLDIMVTD 280 P++ M+ + Sbjct: 383 ATPRILAMLLE 393 >2DQ3-A nrPDB Length = 425 Score = 107 bits (268), Expect = 8e-24, Method: Composition-based stats. Identities = 43/223 (19%), Positives = 83/223 (37%), Gaps = 29/223 (13%) Query: 46 QDLFMTDPLSPGSMFFLPN-GAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSG 104 D LS + GA++ LI FM K G+ E+ P + K + +G Sbjct: 151 LDFKRGAKLSGSRFTVIAGWGARLERALINFMLDLHT-KKGYKEICPPHLVKPEILIGTG 209 Query: 105 HWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNE 164 + +D++K E + P+ ++ ++ LP+ + ++P +R E Sbjct: 210 QLPKFEEDLYKCERDNLYLIPTAEVPL-----TNLYREEILKEENLPIYLTAYTPCYRRE 264 Query: 165 ASG---ALSGLTRLRKFHQDDGHIFCTPSQVKSEIFN-------SLKLIDIVYNKIFPFV 214 A + G+ R +F + + P E+ L+L+ + Y ++ Sbjct: 265 AGAYGKDIRGIIRQHQFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGLPY-RVVELC 323 Query: 215 KGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESG 257 G G FS + D++VW ++ +EI S Sbjct: 324 TGDLG--------FSAAKTY---DIEVWFPSQNKYREISSCSN 355 >3LSS-A nrPDB Length = 484 Score = 90.7 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 40/227 (17%), Positives = 81/227 (35%), Gaps = 15/227 (6%) Query: 54 LSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDM 113 ++ G + L G + L K G+ P + + + + +++ Sbjct: 195 MAGGRSYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVMGEVAQLSQFDEEL 254 Query: 114 FKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASG---ALS 170 ++V + + ++Y + P G+ E PL+++ S R EA Sbjct: 255 YQV--SGDGDKKYLIATSEMPIAAYHRGRWFTELKE-PLKYAGMSTCFRKEAGAHGRDTL 311 Query: 171 GLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIV---YNKIFPFVKGGSGAESNYFIN 227 G+ R+ +F + + + C+P Q E + L+ + +NK S N Sbjct: 312 GIFRVHQFDKIEQFVVCSPRQ--EESWRHLEDMITTSEEFNKSLGLPYRVVNICSGALNN 369 Query: 228 FSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKL 274 + + DL+ W A +E++ S + YGP L Sbjct: 370 AAAKK----YDLEAWFPASGAFRELVSCSNCTDYQSQSVNCRYGPNL 412 >6OTE-A nrPDB Length = 572 Score = 88.0 bits (216), Expect = 8e-18, Method: Composition-based stats. Identities = 45/319 (14%), Positives = 103/319 (32%), Gaps = 71/319 (22%) Query: 52 DPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYAD 111 L+ +FL + I + + + K G+ + P K+ L K+ +++ + Sbjct: 285 AELAGHRGYFLKDYGVIMSMALSHYAMGFLLKKGYLAIQPPYFMKRDLMGKAAELQDFEE 344 Query: 112 DMFKV----ETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASG 167 ++ + + + L + + +LP++++ S R EA Sbjct: 345 TLYHIPSDNSKGEVDSNSLFLIATSEQPIAAMHHNVTLEDKDLPIKYAGISTCFRKEAGA 404 Query: 168 ---ALSGLTRLRKFHQDDGHIFCTPSQ----------VKSEIFNSLKLIDIVYNKIFPFV 214 G+ R+ +F + + P + E + SL+L V + + Sbjct: 405 HGKDTWGIFRIHQFEKVEQFCVTLPEDSQKIHEEMISISEEFYQSLELPYRVISIVSG-- 462 Query: 215 KGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKL 274 +N + + DL+ W +E++ S Sbjct: 463 ----------ALNDAASKKY---DLEAWFPGYNSYRELVSCSN----------------- 492 Query: 275 DIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIM-IHRATFGSIERFMALL 333 TD+ + + +L F+ ++ ++ T +I+R M + Sbjct: 493 ---CTDYQSRALEC---RLGFR-----------KEGEREKHYCHFLNGTLCAIQRTMCCI 535 Query: 334 IDSN----EGRWPFWLNPY 348 +++ R P L PY Sbjct: 536 VENYQTPDGLRIPKVLQPY 554 >4RQF-A nrPDB Length = 522 Score = 88.0 bits (216), Expect = 9e-18, Method: Composition-based stats. Identities = 30/215 (13%), Positives = 80/215 (37%), Gaps = 15/215 (6%) Query: 54 LSPGSMFFLPNGAKIF-NKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADD 112 + GS + G +F + + L+ G+ + TP +K + ++ + ++ Sbjct: 187 VVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEE 246 Query: 113 MFKV-------ETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEA 165 ++KV + E+Y + P L + R +LP++++ S R E Sbjct: 247 LYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRP-EDLPIKYAGLSTCFRQEV 305 Query: 166 SG---ALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAES 222 G+ R+ +F + + ++ +P ++ + + + + + + + Sbjct: 306 GSHGRDTRGIFRVHQFEKIEQFVYSSPHD--NKSWEMFEEMITTAEEFYQSLGIPYHIVN 363 Query: 223 NYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESG 257 + + + DL+ W +E++ S Sbjct: 364 IVSGSLNHAASKKL-DLEAWFPGSGAFRELVSCSN 397 >6GIR-A nrPDB Length = 456 Score = 87.2 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 40/223 (17%), Positives = 79/223 (35%), Gaps = 27/223 (12%) Query: 47 DLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHW 106 D ++ FFL + N+ + L K GF + P +K + K Sbjct: 157 DTKRGAEIAGARGFFLKGDGLMLNQALINFGLTFLKKRGFTGLQPPFFMRKDVMAKCAQL 216 Query: 107 ENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEAS 166 + ++++KV T E ++Y + P + ELPLR++ +S R EA Sbjct: 217 AQFDEELYKV--TGEGDDKYLIATAEQPLCAYHIDEWIHP-TELPLRYAGYSSCFRKEAG 273 Query: 167 G---ALSGLTRLRKFHQDDGHIFCTP---------SQVKSEIFNSLKLIDIVYNKIFPFV 214 G+ R+ +F + + P ++ + + + + Y +I V Sbjct: 274 SHGRDTLGIFRVHQFEKIEQFCITGPNENASWEMLDEMMKNSEDFYQALKLPY-QIVSIV 332 Query: 215 KGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESG 257 G + DL+ W + + +E++ S Sbjct: 333 SGALNDAAAKKY-----------DLEAWFPSSETFRELVSCSN 364 >3QO8-A nrPDB Length = 485 Score = 85.3 bits (209), Expect = 5e-17, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 75/203 (36%), Gaps = 12/203 (5%) Query: 59 MFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVET 118 F G + LI L G+ + P++ K + K+ + ++++KV Sbjct: 178 YFLRNYGVFLNQALIN-YGLSFLSSKGYVPLQAPVMMNKEVMAKTAQLSQFDEELYKV-- 234 Query: 119 TDEEKEEYGLKPMNCPGHCLIFGKKDRS-YNELPLRFSDFSPLHRNEASG---ALSGLTR 174 D E E+Y + P G+ S +LP+R++ +S R EA G+ R Sbjct: 235 IDGEDEKYLIATSEQPISAYHAGEWFESPAEQLPVRYAGYSSCFRREAGSHGKDAWGIFR 294 Query: 175 LRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDH 234 + F + + + P + E + + Y G S N + + Sbjct: 295 VHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEFYQS-LGLPYRVVGIVSGELNNAAAKK-- 351 Query: 235 FIGDLKVWNHAEQVLKEILEESG 257 DL+ W +Q KE++ S Sbjct: 352 --YDLEAWFPFQQEYKELVSCSN 372 >6BLJ-A nrPDB Length = 485 Score = 81.0 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 37/212 (17%), Positives = 77/212 (36%), Gaps = 14/212 (6%) Query: 53 PLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADD 112 + G +FL N ++ + K G+ + TP K +K + ++ Sbjct: 208 QVGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEE 267 Query: 113 MFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASG---AL 169 ++ V T E +++Y + P K+ +ELP+++ S R E Sbjct: 268 LYTV--TGEGEDKYLIATSEQPIAAFHLEKRFDE-SELPIKYCGMSTCFRKEVGAHGKDT 324 Query: 170 SGLTRLRKFHQDDGHIFCTPSQVKS-EIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINF 228 G+ R+ +F + + + +P KS E+F+ + + + S N Sbjct: 325 LGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNA 384 Query: 229 STRPDHFIGDLKVWNHAE---QVLKEILEESG 257 + + DL+ W +E++ S Sbjct: 385 AAKK----FDLEAWFPGADEGNEYRELVSCSN 412 >1WLE-A nrPDB Length = 501 Score = 67.9 bits (164), Expect = 9e-12, Method: Composition-based stats. Identities = 41/241 (17%), Positives = 78/241 (32%), Gaps = 18/241 (7%) Query: 26 ATKNASSATPATMTSMVSQRQDLFMTDPLS--PGSMFFLPNGA-KIFNKLIEFMKLQQKF 82 K A S P ++++ D+ LS G + GA + + L + Sbjct: 176 GDKPAFSFQPRGHLE-IAEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTLNKLI 234 Query: 83 KFGFNEVVTPLIYKKTLWEKSGHWENYAD-DMFKVETTDEEKEEYGLKPMNCPGHCLIFG 141 GF + P + + ++E G N ++ ++ + E+ L G F Sbjct: 235 HRGFTPMTVPDLLRGVVFEGCGMTPNAKPSQIYNIDPS--RFEDLNLAGTAEVGLAGYFM 292 Query: 142 KKDRSYNELPLRFSDFSPLHRNE--ASGALSGLTRLRKFHQDDGHIFCTP--SQVKSEIF 197 ++ +LP+R S +R E GL R+ F + + P Q + Sbjct: 293 DHSVAFRDLPIRMVCSSTCYRAETDTGKEPWGLYRVHHFTKVEMFGVTGPGLEQSSELLE 352 Query: 198 NSLKLIDIVYNKI-FPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEES 256 L L + ++ F + P + D++ W E+ S Sbjct: 353 EFLSLQMEILTELGLHFRVLDMPTQELGL------PAYRKFDIEAWMPGRGRFGEVTSAS 406 Query: 257 G 257 Sbjct: 407 N 407 >2CIM-A nrPDB Length = 522 Score = 67.2 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 34/186 (18%), Positives = 64/186 (34%), Gaps = 30/186 (16%) Query: 55 SPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMF 114 S G P A+IF + + + G+ E++ P + +W KSGH + +++ Sbjct: 220 SRGQWIHGPQSARIFRTFEKIVLEELLEPLGYREMIFPKLVTWEVWMKSGHAKGVYPEIY 279 Query: 115 KVETTDEEKEEYGLK-----------PM-----------------NCPGHCLIFGKKDRS 146 V +Y + P CP + + Sbjct: 280 YVCPPQTRDPDYWEEVADYYKVTHEVPTKLIKEKIAEPIGGMCYAQCPPFWMYVAGETLP 339 Query: 147 YNELPLRFSD-FSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDI 205 E+P++ D HR E+ G + G+ R+ +FH+ + T +V Sbjct: 340 NEEIPVKVFDRSGTSHRYESGG-IHGIERVDEFHRIEIVWIGTKEEVLKCAEELHDRYMH 398 Query: 206 VYNKIF 211 ++N I Sbjct: 399 IFNDIL 404 >5Z5E-A nrPDB Length = 534 Score = 62.1 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 69/364 (18%), Positives = 122/364 (33%), Gaps = 61/364 (16%) Query: 107 ENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNE-LPLRFSDFSPLHRNEA 165 E Y D+ + E E Y L+P G ++F ++ + + LPL + RNE Sbjct: 184 EQYIKDIIERVKKMVENEAY-LRPETAQGPYVMFKREFILHRQKLPLGLAVVGKAFRNEI 242 Query: 166 SGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKI--FPFVKGGSGAESN 223 S L RLR+F Q + IF P + +I + +K + +K Sbjct: 243 SPR-QLLLRLREFTQAELQIFFDPEDNEFDINEVKDVELNFLDKEGNYKRIKVKDLPFPE 301 Query: 224 YFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGP-KLDIMVTDHL 282 ++ F + F L + E+ L+ +L+ + AFY +DI + Sbjct: 302 FYAYFVGKVKQFYERLGI---PEERLRFR--------ELSEKEKAFYNKYHVDIEINFPT 350 Query: 283 RKTHQVATIQL--DFQLPERFDLK----FKDQDNSYKRPIM------IHRATFGSIERFM 330 +V I D L + +DN P + + R I+ F+ Sbjct: 351 YGWKEVGGIHYRTDHDLSGHMKVSGKDLTVQKDNKKFIPHVLELSFGVDRNVLALIDLFL 410 Query: 331 ALLIDSNE--------------GRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNE 376 + E + P L P + + P+ K K++ N Sbjct: 411 T--EEEYEIERDNQKVKEKRVVLKIPKHLAPIKVAVFPLLKKPELIEK-----AKEVYNM 463 Query: 377 LEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRER 436 L+ +F + +G R + Y I + + ++ IR+R Sbjct: 464 LKN-----------YFYPIIYDEQGSIGRRYRRVDEIGVPYAITIDYQTLEDNTVTIRDR 512 Query: 437 DNRK 440 D K Sbjct: 513 DTMK 516 >3W3S-A nrPDB Length = 527 Score = 60.2 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 35/185 (18%), Positives = 59/185 (31%), Gaps = 32/185 (17%) Query: 57 GSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKV 116 G + P A +F L +F+ + K GF + P + + + D M+ V Sbjct: 213 GQWIYTPPMAALFEVLRDFLLERVTRKLGFEPALFPKLIPLETMFRMRYLHGLPDGMYYV 272 Query: 117 -------ETTDEEKEE-----------------------YGLKPMNCPGHCLIFGKKDRS 146 E D+ K E Y L P C + + Sbjct: 273 CPPKRDPELFDDFKRELYVWGELNERTLGSLKEKLRDPGYVLAPAQCEPFYELLRDEVVD 332 Query: 147 YNELPLRFSD-FSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDI 205 LP++ D +R E GA GL R+ +F + + P + L+ Sbjct: 333 PERLPIKLYDCSGWTYRWE-GGAAKGLERVNEFQRIEHVWIAEPEEAYRIRRELLEATKR 391 Query: 206 VYNKI 210 V ++ Sbjct: 392 VAEEL 396 >1B76-A nrPDB Length = 442 Score = 52.5 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 76/474 (16%), Positives = 152/474 (32%), Gaps = 87/474 (18%) Query: 31 SSATPATMTSMVSQRQDLFMTDPLSPGS---MFFLPNGAKIFNKLIE-FMKLQQKFKFGF 86 ++++ + ++ +R +F + + G + P G ++ N L + + + + Sbjct: 1 AASSLDELVALCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDM 60 Query: 87 NEVVTPLIYKKTLWEKSGHWENYADDM-------FKVET--------------TDEEKEE 125 + ++ + + SGH +AD M + Sbjct: 61 EGLDASVLTHRLVLHYSGHEATFADPMVDNAKARYWTPPRYFNMMFQDLRGPRGGRGLLA 120 Query: 126 YGLKPMNCPGHCLIFGK-KDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGH 184 Y L+P G + F D + +L + RNE + + R+R+F Q + Sbjct: 121 Y-LRPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFRNEITPRNF-IFRVREFEQMEIE 178 Query: 185 IFCTPSQVK-------SEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIG 237 F P + + E + + + + P+ + + G Sbjct: 179 YFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKATVDILYRFPHG 238 Query: 238 DLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQL 297 L++ A++ + G L I LR H +T +L ++ Sbjct: 239 SLELEGIAQRT------------DFDLGSHTKDQEALGITAR-VLRNEH--STQRLAYRD 283 Query: 298 PERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNE------------GRWPFWL 345 PE + P +I + G +ALL ++ + L Sbjct: 284 PET---------GKWFVPYVIEPS-AGVDRGVLALLAEAFTREELPNGEERIVLKLKPQL 333 Query: 346 NPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGY 405 P + +IP+ KN ++ T K+L+ L A + V D +G Sbjct: 334 APIKVAVIPL-VKNRPEI---TEYAKRLKARLLALGLGRVLYEDTG----------NIGK 379 Query: 406 RIKSAILKNYSYLIIVG-DEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELE 458 + + + V D Q + R +D ++ TM QI ELE Sbjct: 380 AYRRHDEVGTPFAVTVDYDTIGQSKDGTTRLKDTVTVRDRDTMEQIRLHVDELE 433 >1TKG-A nrPDB Length = 224 Score = 52.1 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 8/26 (30%) Query: 1 MKIQLVRWHCSRNALWNRAFYSTRKA 26 MK W N + Y T A Sbjct: 199 MKTAGAYWRGDSNNKMLQRIYGTAWA 224 >1ATI-A nrPDB Length = 505 Score = 52.1 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 67/382 (17%), Positives = 121/382 (31%), Gaps = 65/382 (17%) Query: 102 KSGHW--ENYADDMFKVETTDEEKEEYG--LKPMNCPGHCLIFGK-KDRSYNELPLRFSD 156 + G W Y + MF+ L+P G + F D + +L + Sbjct: 155 EPGDWTPPRYFNMMFQDLRGPRGGRGLLAYLRPETAQGIFVNFKNVLDATSRKLGFGIAQ 214 Query: 157 FSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVK-------SEIFNSLKLIDIVYNK 209 RNE + + R+R+F Q + F P + + E + + + Sbjct: 215 IGKAFRNEITPRNF-IFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSREN 273 Query: 210 IFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAF 269 + P+ + + G L++ A++ + G Sbjct: 274 LVPYQQPPESSAHYAKATVDILYRFPHGSLELEGIAQRT------------DFDLGSHTK 321 Query: 270 YGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERF 329 L I LR H +T +L ++ PE + P +I + G Sbjct: 322 DQEALGITAR-VLRNEH--STQRLAYRDPET---------GKWFVPYVIEPS-AGVDRGV 368 Query: 330 MALLIDSNE------------GRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNEL 377 +ALL ++ + L P + +IP+ KN ++ T K+L+ L Sbjct: 369 LALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPL-VKNRPEI---TEYAKRLKARL 424 Query: 378 EADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVG-DEEVQLQKYNIRER 436 A + V D +G + + + V D Q + R + Sbjct: 425 LALGLGRVLYEDTG----------NIGKAYRRHDEVGTPFAVTVDYDTIGQSKDGTTRLK 474 Query: 437 DNRKSFEKLTMSQIWEKFIELE 458 D ++ TM QI ELE Sbjct: 475 DTVTVRDRDTMEQIRLHVDELE 496 >3VQX-A nrPDB Length = 291 Score = 49.1 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 73/204 (35%), Gaps = 35/204 (17%) Query: 67 KIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWEN---YADDMFKVETTDEEK 123 K+ ++ F GF E+ +P++ E+ G +N + +F+V+ Sbjct: 82 KLEREITRFFVD-----RGFLEIKSPILIPLEYIERMG-IDNDTELSKQIFRVDKN---- 131 Query: 124 EEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQD-- 181 + L+PM P K DR+ + P++ + P +R E+ G L +F Sbjct: 132 --FCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGKEH----LEEFTMLNF 184 Query: 182 -DGHIFCTPSQVKSEIFNSLKLIDI----------VYNKIFPFVKGGSGAESNYFINFST 230 CT ++S I + L + I VY + G S Sbjct: 185 CQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPL 244 Query: 231 RPDHFIGDLKVWNHAEQVLKEILE 254 + G K W A L+ +L+ Sbjct: 245 DREW--GIDKPWIGAGFGLERLLK 266 >2PME-A nrPDB Length = 693 Score = 47.9 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 3/98 (3%) Query: 113 MFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDR-SYNELPLRFSDFSPLHRNEASGALSG 171 MFK L+P G L F + + +LP + RNE S SG Sbjct: 227 MFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPR-SG 285 Query: 172 LTRLRKFHQDDGHIFCTPSQVKS-EIFNSLKLIDIVYN 208 L R+R+F + F PS+ + N L +Y+ Sbjct: 286 LIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYS 323 Score = 36.0 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 35/91 (38%), Gaps = 7/91 (7%) Query: 36 ATMTSMVSQRQDLFMTDPLS-----PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVV 90 A M + +R F + G F P G + N +I+ + + E+ Sbjct: 68 AKMEDTLKRR--FFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEID 125 Query: 91 TPLIYKKTLWEKSGHWENYADDMFKVETTDE 121 ++ + + + SGH + +AD M K E Sbjct: 126 CTMLTPEPVLKTSGHVDKFADFMVKDVKNGE 156 >6JP2-A nrPDB Length = 278 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 41/132 (31%), Gaps = 13/132 (9%) Query: 77 KLQQKFKFGFNEVVTPLIYKKTLWEKSGHWEN--YADDMFKVETTDEEKEEYGLKPMNCP 134 GF EV TP+ K + E+ +F + E+ L+PM P Sbjct: 73 IADALVAEGFIEVRTPIFISKDALARMTITEDKPLFKQVFWI------DEKRALRPMLAP 126 Query: 135 GHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKS 194 + R + + P++ + R E+ L +F + Sbjct: 127 NLYSVMRD-LRDHTDGPVKIFEMGSCFRKESHSG----MHLEEFTMLNLVDMGPRGDATE 181 Query: 195 EIFNSLKLIDIV 206 + N + ++ Sbjct: 182 VLKNYISVVMKA 193 >1QE0-A nrPDB Length = 420 Score = 44.4 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 63/427 (14%), Positives = 137/427 (32%), Gaps = 52/427 (12%) Query: 53 PLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKS--GHWENYA 110 + G+ LP +K + + + + + + E+ TP+ L+ + + Sbjct: 3 KIPRGTQDILPEDSKKWRYIENQL-DELMTFYNYKEIRTPIFESTDLFARGVGDSTDVVQ 61 Query: 111 DDMFKVETTDEEKEEYGLKPMNCPGHCLIF-GKKDRSYNELPLRFSDFSPLHRNEASGAL 169 +M+ + D+ L+P + K + P++ P+ R E Sbjct: 62 KEMYTFK--DKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQ-- 117 Query: 170 SGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFS 229 G R R+F+Q + L ++ +Y F N + + Sbjct: 118 KG--RYRQFNQFGVEAIGAENPSVDA--EVLAMVMHIYQ---SFGLKHLKLVINSVGDMA 170 Query: 230 TRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNP-----------GDGAFYGPKL-DIM 277 +R ++ + + H E V+ E + +P + P++ D + Sbjct: 171 SRKEY---NEALVKHFEPVIHEFCSDCQSRLHTDPMRILDCKVDRDKEAIKTAPRITDFL 227 Query: 278 VTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRP----IMIHRATFGSIERFMALL 333 + QV D +P D + Y +M + G+I Sbjct: 228 NEESKAYYEQVKAYLDDLGIPYTEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTL--CG 285 Query: 334 IDSNEGRWPFWLNPYQAVI-----IPVNTKNVQQLDMCTALQKKL----RNELEADDMEP 384 G P + I I +++ + +++ L + D Sbjct: 286 GGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYA 345 Query: 385 VPLNDW----HFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRK 440 V L + D D + ++K A + I++GD+E++ K +++ N Sbjct: 346 VKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVK---NMT 402 Query: 441 SFEKLTM 447 + E T+ Sbjct: 403 TGESETI 409 >4E51-A nrPDB Length = 467 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 34/185 (18%), Positives = 63/185 (34%), Gaps = 15/185 (8%) Query: 26 ATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFG 85 T A + P +MT + + L G LP A ++ +K + +G Sbjct: 10 GTLEAQTQGPGSMTEQKRKLEKLTGVK----GMNDILPQDAGLWEFFEATVKSLLRA-YG 64 Query: 86 FNEVVTPLIYKKTLW-EKSGHW-ENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKK 143 + + TP++ L+ G + +M+ E L+P N + + Sbjct: 65 YQNIRTPIVEHTPLFTRGIGEVTDIVEKEMYSFVDA-LNGENLTLRPEN-TAAVVRAAIE 122 Query: 144 DRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQ--DDGHIFCTPSQVKSEIFNSLK 201 + P R P+ R+E R R+FHQ + F P + + Sbjct: 123 HNMLYDGPKRLWYIGPMFRHERPQRG----RYRQFHQVGVEALGFAGPDADAEIVMMCQR 178 Query: 202 LIDIV 206 L + + Sbjct: 179 LWEDL 183 >2ZNJ-A nrPDB Length = 308 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 66/165 (40%), Gaps = 18/165 (10%) Query: 83 KFGFNEVVTPLIYKKTLWEKSGHWENYA--DDMFKVETTDEEKEEYGLKPMNCPGHCLIF 140 + GF +VVTP I K+ K E++ +F ++ L+PM P ++ Sbjct: 106 QQGFVQVVTPTIITKSALAKMTIGEDHPLFSQVFWLDGKK------CLRPMLAPNLYTLW 159 Query: 141 GKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSL 200 + +R +++ P+R + +R E+ GA L +F + TP E L Sbjct: 160 RELERLWDK-PIRIFEIGTCYRKESQGAQH----LNEFTMLNLTELGTP---LEERHQRL 211 Query: 201 KLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHA 245 + + + + ES+ + D GDL++ + A Sbjct: 212 EDMARWVLEAAGIREFELVTESSVV--YGDTVDVMKGDLELASGA 254 >1ADJ-A nrPDB Length = 421 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 52/405 (12%), Positives = 125/405 (30%), Gaps = 28/405 (6%) Query: 50 MTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKS--GHWE 107 MT G+ ++ +++ + + G E+VTP+ + ++EK + Sbjct: 1 MTARAVRGTKDLFGKELRMHQRIVATAR-KVLEAAGALELVTPIFEETQVFEKGVGAATD 59 Query: 108 NYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASG 167 +MF + D L+P + + P+R P+ R E Sbjct: 60 IVRKEMFTFQ--DRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAE--- 114 Query: 168 ALSGLTRLRKFHQDDGHIFCTPSQVKSE-----IFNSLKLID--IVYNKIFPFVKGGSGA 220 R R+FHQ + + + + ++ LK + + K+ A Sbjct: 115 -RPQKGRYRQFHQVNYEALGSENPILDAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRA 173 Query: 221 ESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGA------FYGPKL 274 N ++ P E+ IL+ + + + F G + Sbjct: 174 RYNAYLREVLSPHREALSEDSKERLEENPMRILDSKSERDQALLKELGVRPMLDFLGEEA 233 Query: 275 DIMVTDHLRKTHQVAT-IQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALL 333 + + R +++ +L+ L D + + ++ G R+ L Sbjct: 234 RAHLKEVERHLERLSVPYELEPALVRGLDY-YVRTAFEVHHEEIGAQSALGGGGRYDGLS 292 Query: 334 IDSNEGRWP---FWLNPYQAVI-IPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLND 389 R P F + + + + + L E A+ Sbjct: 293 ELLGGPRVPGVGFAFGVERVALALEAEGFGLPEEKGPDLYLIPLTEEAVAEAFYLAEALR 352 Query: 390 WHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIR 434 + + ++ A+ + ++ +G++E++ + ++ Sbjct: 353 PRLRAEYALAPRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLK 397 >5XIX-A nrPDB Length = 472 Score = 34.4 bits (77), Expect = 0.096, Method: Composition-based stats. Identities = 30/187 (16%), Positives = 57/187 (30%), Gaps = 32/187 (17%) Query: 70 NKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSG--HWENYADDMFKVETTDEEKEEYG 127 ++ F G+ EV P + + + + + + ++ F +++ E Sbjct: 173 RSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYL-ETC 231 Query: 128 LKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHI-F 186 L P C + +R E S L ++ + F Sbjct: 232 L-PALGDVFC-------------------IAQSYRAEQSRTRRHLA---EYTHVEAECPF 268 Query: 187 CTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFI--GDLKVWNH 244 T + + + + L+ V ++I G E N RP + D VW Sbjct: 269 LTFDDLLNRLED---LVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLK 325 Query: 245 AEQVLKE 251 V KE Sbjct: 326 EHDVKKE 332 >4UJ3-B nrPDB Length = 195 Score = 34.0 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 26/190 (13%), Positives = 52/190 (27%), Gaps = 14/190 (7%) Query: 36 ATMTSMVSQRQDLFMTDPLSPGSM---FFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTP 92 +T ++M QDL + P+ L N +++ + + E + P Sbjct: 7 STSSAMSGSHQDLSVIQPIVKDCKEADLSLYNEFRLWKDEPTMDRTCPFLDKIYQEDIFP 66 Query: 93 LIYKKTLWEKSGHWENYADDMFKVETTDEEKEEY-------GLKPMNCPGHCLIFGKKDR 145 + S E ++ +E + + P C K R Sbjct: 67 CLTFSKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKSCKHR 126 Query: 146 SYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDI 205 + SP R + + T +R Q V + ++L Sbjct: 127 IKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQG----LVKQQDVDQMFWEVMQLRKE 182 Query: 206 VYNKIFPFVK 215 + + K Sbjct: 183 MSLAKLGYFK 192 >3NET-A nrPDB Length = 465 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 50/140 (35%), Gaps = 21/140 (15%) Query: 56 PGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMF- 114 G FLP+ ++ L++ ++ +GF + TP + + + + G N D++ Sbjct: 16 SGFPEFLPSEKRLELYLLDTIRR-VYESYGFTPIETPAVERLEVLQAKG---NQGDNIIY 71 Query: 115 ---KVETTDEEKEEYGLKPMNCPGHCLIFGKKD-------RSYNEL--PLRFSDFSPLHR 162 + + + E+ L F + R N+L P + R Sbjct: 72 GLEPILPPNRQAEKDKSGDTGSEARALKFDQTVPLAAYIARHLNDLTFPFARYQMDVVFR 131 Query: 163 NEASGALSGLTRLRKFHQDD 182 E + R R+F Q D Sbjct: 132 GERAKDG----RFRQFRQCD 147 >2OC2-A nrPDB Length = 591 Score = 33.3 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 36/120 (30%), Gaps = 15/120 (12%) Query: 62 LPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSG---------HWENYADD 112 L G E G V K L + + W+ Y Sbjct: 270 LKQGWTPRRMFKE--ADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGK 327 Query: 113 MFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGL 172 F+++ E + + GH F + Y +LP+ + + +EA G + L Sbjct: 328 DFRIKQCTTVNLEDLVVAHHEMGHIQYFMQ----YKDLPVALREGANPGFHEAIGDVLAL 383 >4AH6-A nrPDB Length = 617 Score = 32.9 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 33/215 (15%), Positives = 71/215 (33%), Gaps = 32/215 (14%) Query: 29 NASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNE 88 NA P + + V + + L + F + ++ ++++ M+ GF + Sbjct: 111 NACKKLPFEIKNFVKKTEALRLQYRYLDLRSFQMQYNLRLRSQMVMKMREYLCNLHGFVD 170 Query: 89 VVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYN 148 + TP ++K+ T +E+ L P PG + + + Sbjct: 171 IETPTLFKR---------------------TPGGAKEF-LVPSREPGKFYSLPQSPQQFK 208 Query: 149 ELPL-----RFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLI 203 +L + R+ + +R+E S R +F Q D + + L Sbjct: 209 QLLMVGGLDRYFQVARCYRDEGSRPD----RQPEFTQIDIEMSFVDQTGIQSLIEGLLQY 264 Query: 204 DIVYNKIFPFVKGGSGAESNYFINF-STRPDHFIG 237 +K V + + + + +PD G Sbjct: 265 SWPNDKDPVVVPFPTMTFAEVLATYGTDKPDTRFG 299 >3NEM-A nrPDB Length = 438 Score = 31.7 bits (70), Expect = 0.73, Method: Composition-based stats. Identities = 21/173 (12%), Positives = 57/173 (32%), Gaps = 20/173 (11%) Query: 97 KTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPL---- 152 + + ++G E + + T + L PM + + Y ++ + Sbjct: 148 RDFFHENGFIEIHTPKIIATATEGGTE----LFPMKYFEEDAFLAQSPQLYKQIMMASGL 203 Query: 153 -RFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIF 211 R + +P+ R E H ++ + + + ++ + Sbjct: 204 DRVYEIAPIFRAEEHNTTR--------HLNEAWSIDSEMAFIEDEEEVMSFLERLVAHAI 255 Query: 212 PFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNP 264 +V+ + E + +NF ++ A ++L ++ +E PW + Sbjct: 256 NYVREHNAKELDI-LNFELEEPKLPFPRVSYDKALEILGDLGKE--IPWGEDI 305 >4WJ3-M nrPDB Length = 599 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 44/254 (17%), Positives = 85/254 (33%), Gaps = 32/254 (12%) Query: 24 RKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIE--------- 74 KA + S +T V R + ++ GS+ L ++ N+ Sbjct: 67 AKADR-VRSEFVVKITGKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYS 125 Query: 75 FMKLQQKFKFGFNEVVTPLIYKKTLWEK--SGHWENYADDMFKV--------ETTDEEKE 124 + + + ++ F ++ P + K + Y DD + T E Sbjct: 126 DVGEETRLRYRFIDLRRPEMAAKLKLRARITSSIRRYLDDNGFLDVETPILGRPTPEGAR 185 Query: 125 EYGLKPMNCPGHCLIFGKKDRSYNELPL-----RFSDFSPLHRNEASGALSGLTRLRKFH 179 +Y + PGH + + + +L + R+ + R+E A R +F Sbjct: 186 DYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRAD----RQPEFT 241 Query: 180 QDD-GHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGD 238 Q D F S + ++ + + E S +PD I Sbjct: 242 QIDIETSFLDESDIIGITEKMVRQLFKEVLDVEFDEFPHMPFEEAMRRYGSDKPDLRIP- 300 Query: 239 LKVWNHAEQVLKEI 252 L++ + A+Q LKE+ Sbjct: 301 LELVDVADQ-LKEV 313 >2DU7-A nrPDB Length = 549 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 9/29 (31%) Query: 148 NELPLRFSDFSPLHRNEASGALSGLTRLR 176 +LPL+ R E S L Sbjct: 214 RKLPLKLFSIDRCFRREQREDRSHLMSYH 242 >5SWI-B nrPDB Length = 717 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 26/66 (39%), Gaps = 3/66 (4%) Query: 327 ERFMALLIDSNE--GRWPFWLNPYQAVIIPVNTKNVQQLDM-CTALQKKLRNELEADDME 383 +RF+ ++S G P WL P + ++P + D C + L EL +E Sbjct: 349 QRFLEGFLNSYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLE 408 Query: 384 PVPLND 389 D Sbjct: 409 TASKAD 414 >1EFW-A nrPDB Length = 580 Score = 30.6 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 27/179 (15%), Positives = 51/179 (28%), Gaps = 37/179 (20%) Query: 66 AKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEE 125 ++ + +F+ + GF +V TP + K T E + Sbjct: 148 HRVIKAIWDFLDRE-----GFVQVETPFLTKS---------------------TPEGARD 181 Query: 126 YGLKPMNCPGHCLIFGKKDRSYNELPL-----RFSDFSPLHRNEASGALSGLTRLRKFHQ 180 + + + PG + + + ++ + R+ + R+E A R F Q Sbjct: 182 FLVPYRHEPGLFYALPQSPQLFKQMLMVAGLDRYFQIARCFRDEDLRAD----RQPDFTQ 237 Query: 181 DD-GHIFCTPSQVKSEIFNSL-KLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIG 237 D F V + + P E S +PD G Sbjct: 238 LDLEMSFVEVEDVLELNERLMAHVFREALGVELPLPFPRLSYEEAMERYGSDKPDLRFG 296 >3RWL-A nrPDB Length = 426 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 32/112 (28%), Gaps = 16/112 (14%) Query: 151 PLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKI 210 P + R S L GL +F D +Q+ + +F+ Sbjct: 132 PANLAALEGTIRERVSKTLDGLPVGEEFDWVDRVSIEITTQMLATLFD------------ 179 Query: 211 FPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKL 262 FPF + + T G ++ W+ + L E W Sbjct: 180 FPFEERRKLTRWSDV----TTAAPGGGVVESWDQRKTELLECAAYFQVLWNE 227 >4BGV-A nrPDB Length = 323 Score = 30.2 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 34/78 (43%) Query: 201 KLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPW 260 + +++ + + FV GG G + FI +S I DL ++++K G+ Sbjct: 163 QELNVSFEDVNAFVIGGHGDDMVPFIRYSNVSGIPIEDLLPREKIDEIVKRTRFGGGEIV 222 Query: 261 KLNPGDGAFYGPKLDIMV 278 L AFY P + I V Sbjct: 223 NLYKTGSAFYAPGISIAV 240 >2PVQ-A nrPDB Length = 201 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 44/127 (34%), Gaps = 15/127 (11%) Query: 303 LKFKDQDNSYKRPIMIHRATFGSIER--------FMALLIDSNEGRWPFWLN--PYQAVI 352 L++ + + + +GSIER F + L + G + L+ VI Sbjct: 70 LQYIGDHSD----VAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVI 125 Query: 353 IPVNTKNVQQLDMCTA-LQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAI 411 +N + Q M + L ++ D + W LD+ P +++ + Sbjct: 126 ANINRRLGQLEAMLSDKNAYWLGDDFTQPDAYASVIIGWGVGQKLDLSAYPKALKLRERV 185 Query: 412 LKNYSYL 418 L + Sbjct: 186 LARPNVQ 192 >2ODR-C nrPDB Length = 701 Score = 29.8 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 6/29 (20%), Positives = 7/29 (24%) Query: 148 NELPLRFSDFSPLHRNEASGALSGLTRLR 176 LP + R E S L Sbjct: 221 KPLPFKLFSIDRCFRREQKEDKSHLMTYH 249 >5MLQ-A nrPDB Length = 248 Score = 29.4 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 23/48 (47%), Gaps = 1/48 (2%) Query: 34 TPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQK 81 P +++ + + ++LF+ P P + +LP K + + +Q+ Sbjct: 195 YPQRISAAMGRTRELFVV-PEHPDRVAWLPLRFKKRKSALHGAREEQR 241 >5JNF-C nrPDB Length = 587 Score = 29.4 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 42/141 (29%), Gaps = 14/141 (9%) Query: 16 WNRAFYSTRKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEF 75 W R ++ A K A + S D+F L+ ++ +P+ K Sbjct: 376 WYRPYFGVTPADK----ALVYSSFSFDGSALDIFT-HLLAGAALHIVPSE----RKYDLD 426 Query: 76 MKLQQKFKFGFNEVVTPLIYKKTLWEKSGH----WENYADDMFKVETTDEEKEEYGLKPM 131 + G P + + D + K+E K G P Sbjct: 427 ALNDYCNQEGITISYLPTGAAEQFMQMDNQSFRVVITGGDVLKKIERNGTYKLYNGYGPT 486 Query: 132 NCPGHCLIFGKKDRSYNELPL 152 C +F D+ Y +P+ Sbjct: 487 ECTIMVTMFEV-DKPYANIPI 506 >5ES6-A nrPDB Length = 685 Score = 29.4 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 42/141 (29%), Gaps = 14/141 (9%) Query: 16 WNRAFYSTRKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEF 75 W R ++ A K A + S D+F L+ ++ +P+ K Sbjct: 374 WYRPYFGVTPADK----ALVYSSFSFDGSALDIFT-HLLAGAALHIVPSE----RKYDLD 424 Query: 76 MKLQQKFKFGFNEVVTPLIYKKTLWEKSGH----WENYADDMFKVETTDEEKEEYGLKPM 131 + G P + + D + K+E K G P Sbjct: 425 ALNDYCNQEGITISYLPTGAAEQFMQMDNQSFRVVITGGDVLKKIERNGTYKLYNGYGPT 484 Query: 132 NCPGHCLIFGKKDRSYNELPL 152 C +F D+ Y +P+ Sbjct: 485 ECTIMVTMFEV-DKPYANIPI 504 >5ES8-A nrPDB Length = 776 Score = 29.4 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 42/141 (29%), Gaps = 14/141 (9%) Query: 16 WNRAFYSTRKATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEF 75 W R ++ A K A + S D+F L+ ++ +P+ K Sbjct: 374 WYRPYFGVTPADK----ALVYSSFSFDGSALDIFT-HLLAGAALHIVPSE----RKYDLD 424 Query: 76 MKLQQKFKFGFNEVVTPLIYKKTLWEKSGH----WENYADDMFKVETTDEEKEEYGLKPM 131 + G P + + D + K+E K G P Sbjct: 425 ALNDYCNQEGITISYLPTGAAEQFMQMDNQSFRVVITGGDVLKKIERNGTYKLYNGYGPT 484 Query: 132 NCPGHCLIFGKKDRSYNELPL 152 C +F D+ Y +P+ Sbjct: 485 ECTIMVTMFEV-DKPYANIPI 504 >5Y7F-A nrPDB Length = 293 Score = 28.6 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 24/63 (38%), Gaps = 3/63 (4%) Query: 86 FNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPM-NCPGHCLIFGKKD 144 F +V+ PL K ++ + DM+ + D E YG PM + F Sbjct: 91 FLDVLFPLSLDKVIFVDADQI--VRTDMYDLVQLDLEGAPYGFTPMCDSRKEMEGFRFWK 148 Query: 145 RSY 147 + Y Sbjct: 149 QGY 151 >5MPB-R nrPDB Length = 429 Score = 28.6 bits (62), Expect = 6.3, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 31/93 (33%), Gaps = 1/93 (1%) Query: 321 ATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKK-LRNELEA 379 A ++L +P+ L Y V+IP N +++K LE+ Sbjct: 285 ALQSISSLTISLYASDYASYFPYLLETYANVLIPCKYLNRHADFFVREMRRKVYAQLLES 344 Query: 380 DDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAIL 412 + F V + + +G I + L Sbjct: 345 YKTLSLKSMASAFGVSVAFLDNDLGKFIPNKQL 377 >2D1L-A nrPDB Length = 253 Score = 28.3 bits (61), Expect = 8.2, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 47/126 (37%), Gaps = 8/126 (6%) Query: 314 RPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKL 373 R M HR+ + +F + LID +NP Q + Q KK Sbjct: 84 RMCMRHRSIEAKLRQFSSALID-------CLINPLQEQMEEWKKVANQLDKDHAKEYKKA 136 Query: 374 RNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNI 433 R E++ + + L VD R + + ++ SA+ +++ + E Q + + Sbjct: 137 RQEIKKKSSDTLKLQKKAKKVDAQGRGD-IQPQLDSALQDVNDKYLLLEETEKQAVRKAL 195 Query: 434 RERDNR 439 E R Sbjct: 196 IEERGR 201 >5ZG8-A nrPDB Length = 438 Score = 28.3 bits (61), Expect = 8.3, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 37/132 (28%), Gaps = 24/132 (18%) Query: 62 LPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDE 121 P +E + + GF P++ + + ++F+VE D Sbjct: 126 RPFAVMRIRDELERAIHEFFGERGFLRFDAPILTPSAVEGTT--------ELFEVELFDG 177 Query: 122 EKEEYGL-KPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQ 180 EK + L F + F P R E S L +F Sbjct: 178 EKAYLSQSGQLYAEAGALAFA-----------KVYTFGPTFRAERSKTRRHLL---EFWM 223 Query: 181 DD-GHIFCTPSQ 191 + F T + Sbjct: 224 VEPEVAFMTHEE 235 >2XGT-A nrPDB Length = 435 Score = 27.9 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 7/49 (14%), Positives = 20/49 (40%), Gaps = 2/49 (4%) Query: 78 LQQKFKFGFNEVVTPLIYKKTLWEKSG--HWENYADDMFKVETTDEEKE 124 + + G+ EV P + + + S + + + + F +++ E Sbjct: 143 REHFYNAGYVEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQLYLE 191 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.121 0.298 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,411,056 Number of Sequences: 36641 Number of extensions: 576878 Number of successful extensions: 1695 Number of sequences better than 10.0: 69 Number of HSP's better than 10.0 without gapping: 54 Number of HSP's successfully gapped in prelim test: 45 Number of HSP's that attempted gapping in prelim test: 1473 Number of HSP's gapped (non-prelim): 119 length of query: 462 length of database: 10,336,785 effective HSP length: 100 effective length of query: 362 effective length of database: 6,672,685 effective search space: 2415511970 effective search space used: 2415511970 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.9 bits)