BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P06999 (309 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3N1C-A nrPDB 626 e-180 2JG5-A nrPDB 141 3e-34 2ABQ-A nrPDB 141 3e-34 2AWD-A nrPDB 122 3e-28 3JUL-A nrPDB 100 1e-21 2Q5R-A nrPDB 89 2e-18 2AJR-A nrPDB 72 3e-13 1VM7-A nrPDB 60 1e-09 6ILS-A nrPDB 55 5e-08 3KZH-A nrPDB 52 3e-07 5EYN-A nrPDB 52 3e-07 5C40-A nrPDB 47 9e-06 2NWH-A nrPDB 46 3e-05 3GBU-A nrPDB 44 1e-04 1TYY-A nrPDB 42 3e-04 3RY7-A nrPDB 40 0.001 3PL2-A nrPDB 40 0.001 5ZWY-A nrPDB 39 0.003 1RK2-A nrPDB 37 0.010 3H49-A nrPDB 35 0.029 4X8F-A nrPDB 35 0.049 2HW1-A nrPDB 35 0.058 3NCA-A nrPDB 35 0.060 3GO6-A nrPDB 34 0.065 3HJ6-A nrPDB 34 0.098 4WB0-B nrPDB 32 0.38 1TD2-A nrPDB 31 0.60 3A42-A nrPDB 31 0.71 5XV0-A nrPDB 31 0.81 3L73-B nrPDB 30 1.3 3RC8-A nrPDB 29 2.1 3KTN-A nrPDB 29 2.1 2QI2-A nrPDB 29 2.1 2VAR-A nrPDB 29 2.4 4N08-A nrPDB 28 3.6 2O1M-A nrPDB 28 4.1 4MKS-A nrPDB 28 5.0 4DU5-A nrPDB 28 5.2 4LC4-A nrPDB 28 5.5 3PB0-A nrPDB 28 7.3 3IQ0-A nrPDB 28 7.4 3LU2-A nrPDB 27 9.2 >3N1C-A nrPDB Length = 309 Score = 626 bits (1615), Expect = e-180, Method: Compositional matrix adjust. Identities = 309/309 (100%), Positives = 309/309 (100%) Query: 1 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP 60 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP Sbjct: 1 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP 60 Query: 61 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ 120 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ Sbjct: 61 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ 120 Query: 121 LEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN 180 LEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN Sbjct: 121 LEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN 180 Query: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ 240 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ Sbjct: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ 240 Query: 241 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDT 300 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDT Sbjct: 241 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDT 300 Query: 301 QKIYAYLSR 309 QKIYAYLSR Sbjct: 301 QKIYAYLSR 309 >2JG5-A nrPDB Length = 306 Score = 141 bits (356), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 93/300 (31%), Positives = 153/300 (51%), Gaps = 7/300 (2%) Query: 4 IYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGG 63 IYT+T PS+D T +G R TA GG GINV+R + L +TA+ AGG Sbjct: 2 IYTVTFNPSIDYVIFTNDFKIDGLNRATATYKFAGGKGINVSRVLKTLDVESTALGFAGG 61 Query: 64 ATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEE 123 G+ ++ L + + +E + TR N+ + +G++ PG + +F QL + Sbjct: 62 FPGKFIIDTLNNSAIQSNFIEVDEDTRINVKLK---TGQETEINAPGPHITSTQFEQLLQ 118 Query: 124 QVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIEL 183 Q+ S I++++GS+P + + Q+ + G + +VD+ E + L + Sbjct: 119 QIKNTTSEDIVIVAGSVPSSIPSDAYAQIAQITAQTGAKLVVDAEKELAESVLPYHPL-F 177 Query: 184 VKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVP 243 +KPN+ EL + N + DV K + +V+ G A+ V+VSLG GA+ +D E I+ V Sbjct: 178 IKPNKDELEVMFNTTVNSDADVIKYGRLLVDKG-AQSVIVSLGGDGAIYIDKEISIKAVN 236 Query: 244 PPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKI 303 P K +TVG+GDS V M +A S+E+ + VA G+A ++ L + D +KI Sbjct: 237 PQGKVVNTVGSGDSTVAGMVAGIASGLSIEKAFQQAVACGTATAFDE--DLATRDAIEKI 294 >2ABQ-A nrPDB Length = 306 Score = 141 bits (356), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 102/308 (33%), Positives = 163/308 (52%), Gaps = 11/308 (3%) Query: 4 IYTLTLAPSLDSATITPQIYPEGKL-RCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG 62 IYT+TL PS+D + + + +G + R +PGG GINV+R + LG A+ G Sbjct: 2 IYTVTLNPSIDY-IVQVENFQQGVVNRSERDRKQPGGKGINVSRVLKRLGHETKALGFLG 60 Query: 63 GATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ-L 121 G TG ++ + L E + ++ +E + TR ++V+ G+Q + A L + E Q L Sbjct: 61 GFTGAYVRNALEKEEIGLSFIEVEGDTR----INVKIKGKQETELNGTAPLIKKEHVQAL 116 Query: 122 EEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNI 181 EQ+ E+E G +LV++GS+P + + A+++G VD+SGEAL LA Sbjct: 117 LEQLTELEKGDVLVLAGSVPQAMPQTIYRSMTQIAKERGAFVAVDTSGEALHEVLA-AKP 175 Query: 182 ELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQV 241 +KPN ELS LV++ + +D Q ++ G + ++VS GAL +E V Sbjct: 176 SFIKPNHHELSELVSKPIASIEDAIPHVQRLIGEG-IESILVSFAGDGALFASAEGMFHV 234 Query: 242 VPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQ 301 P + +++VGAGDS+V L E SLE+ V F VAAGSA + G C+ ++ + Sbjct: 235 NVPSGEVRNSVGAGDSVVAGFLAALQEGKSLEDAVPFAVAAGSATAFSDG--FCTREEVE 292 Query: 302 KIYAYLSR 309 ++ L R Sbjct: 293 RLQQQLQR 300 >2AWD-A nrPDB Length = 323 Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 88/311 (28%), Positives = 159/311 (51%), Gaps = 10/311 (3%) Query: 1 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP 60 M I T+T+ PS+D + + + + R + PGG G+NV R I LGG A Sbjct: 1 MSLIVTVTMNPSIDISYLLDHLKLDTVNRTSQVTKTPGGKGLNVTRVIHDLGGDVIATGV 60 Query: 61 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ 120 GG G + + L N+P A K+ TR ++ + E G Q + G ++ +E Sbjct: 61 LGGFHGAFIANELKKANIPQAFTSIKEETRDSIAILHE--GNQTEILEAGPTVSPEEISN 118 Query: 121 LEEQVLE-IESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAAL-AI 178 E + I+ I+ ISGSL G+ + +L+ A Q ++ ++D+SG++L L Sbjct: 119 FLENFDQLIKQAEIVTISGSLAKGLPSDFYQELVQKAHAQEVKVLLDTSGDSLRQVLQGP 178 Query: 179 GNIELVKPNQKELSALVNRELTQPD--DVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSE 236 L+KPN +EL L+ ++ ++ V+ A + + +G + +V+SLG GA+ + Sbjct: 179 WKPYLIKPNLEELEGLLGQDFSENPLAAVQTALTKPMFAG-IEWIVISLGKDGAIAKHHD 237 Query: 237 NCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCS 296 +V P +++++ VG+GD+ + + LA++A E++++G+AAG A N R+ Sbjct: 238 QFYRVKIPTIQAKNPVGSGDATIAGLAYGLAKDAPAAELLKWGMAAGMA---NAQERMTG 294 Query: 297 HDDTQKIYAYL 307 H D + + +L Sbjct: 295 HVDVENVKKHL 305 >3JUL-A nrPDB Length = 320 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 80/291 (27%), Positives = 148/291 (50%), Gaps = 13/291 (4%) Query: 1 MVRIYTLTLAPSLDSAT-ITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIF 59 M IYT+TL P++D I ++ R F+ GG G++V+ ++ G A+ Sbjct: 1 MSLIYTITLNPAIDRLLFIRGELEKRKTNRVIKTEFDCGGKGLHVSGVLSKFGIKNEALG 60 Query: 60 PAGGATGEHLVSLLADENVPV-ATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEF 118 AG + L ++L ++++ VEA TR+ V + + G +++ Sbjct: 61 IAGSDNLDKLYAILKEKHINHDFLVEAGTSTRECFVVLSDDTNGSTMIPEAGFTVSQTNK 120 Query: 119 RQLEEQVLE-IESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALA 177 L +Q+ + ++ ++VI+GS PP L +L+ + G D+SGE L+ A+ Sbjct: 121 DNLLKQIAKKVKKEDMVVIAGSPPPHYTLSDFKELLRTVKATGAFLGCDNSGEYLNLAVE 180 Query: 178 IGNIELVKPNQKELSALVNRELTQ-PDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSE 236 +G ++ +KPN+ E+ A+++ + +++R A++I +VVSLG +G++ + Sbjct: 181 MG-VDFIKPNEDEVIAILDEKTNSLEENIRTLAEKI------PYLVVSLGAKGSICAHNG 233 Query: 237 NCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAAT 287 QV+PP V+ ++ GAGD VGA LA N + E ++ VA G +A+ Sbjct: 234 KLYQVIPPKVQERNDTGAGDVFVGAFIAGLAMNMPITETLK--VATGCSAS 282 >2Q5R-A nrPDB Length = 330 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 81/280 (28%), Positives = 135/280 (48%), Gaps = 12/280 (4%) Query: 4 IYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGG 63 I TLTL PS+D + + + R GG G+NV R +A +G A GG Sbjct: 22 ILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGG 81 Query: 64 ATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDE---FRQ 120 G+ + L ++ A K TR + + E G+Q + G ++ E F + Sbjct: 82 ELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHE--GQQTEILEQGPEIDNQEAAGFIK 139 Query: 121 LEEQVLE-IESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAI- 178 EQ+LE +E+ AI SGSLP G+ + Q+I Q +G+ I+D SG L L Sbjct: 140 HFEQLLEKVEAVAI---SGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENP 196 Query: 179 GNIELVKPNQKELSALVNRELTQP-DDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSEN 237 ++KPN EL L+N+ L + + +++A + + G + ++VSLG QGA + Sbjct: 197 YKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEG-IEWIIVSLGAQGAFAKHNHT 255 Query: 238 CIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVR 277 +V P + + VG+GDS V +T + + + ++++ Sbjct: 256 FYRVNIPTISVLNPVGSGDSTVAGITSAILNHENDHDLLK 295 >2AJR-A nrPDB Length = 331 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 80/317 (25%), Positives = 142/317 (44%), Gaps = 16/317 (5%) Query: 4 IYTLTLAPSLDSATITP-----QIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAI 58 + T+TL P+LD ++Y L T PGG GINV+ A++ LG + A Sbjct: 14 VLTVTLNPALDREIFIEDFQVNRLYRINDLSKTQ--MSPGGKGINVSIALSKLGVPSVAT 71 Query: 59 FPAGGATGEHLVSLLADENVPVAT--VEAKDWTRQNLHVHVEASGEQYRFVMPGAALNE- 115 GG G+ LV L + + T V + TR+N+ + E + PG + + Sbjct: 72 GFVGGYMGKILVEELRKISKLITTNFVYVEGETRENIEIIDEKNKTITAINFPGPDVTDM 131 Query: 116 DEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAA 175 D L + + +VISGS+PPGV +L+ A+++G+ V+ + L Sbjct: 132 DVNHFLRRYKMTLSKVDCVVISGSIPPGVNEGICNELVRLARERGVFVFVEQTPRLLERI 191 Query: 176 LAIGNI-ELVKPNQK-ELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGV 233 +VKP+ + ++ + +L DD K A+++ + K++ VVS + + Sbjct: 192 YEGPEFPNVVKPDLRGNHASFLGVDLKTFDDYVKLAEKL--AEKSQVSVVSYEVKNDIVA 249 Query: 234 DSENCIQV-VPPPVKSQSTVGAGDSMVGAMTLKLAEN-ASLEEMVRFGVAAGSAATLNQG 291 E + + + +GAGD+ V M ++ A+ EM +FG A+ AAT + Sbjct: 250 TREGVWLIRSKEEIDTSHLLGAGDAYVAGMVYYFIKHGANFLEMAKFGFASALAATRRKE 309 Query: 292 TRLCSHDDTQKIYAYLS 308 + + +K Y + + Sbjct: 310 KYMPDLEAIKKEYDHFT 326 >1VM7-A nrPDB Length = 311 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 64/271 (23%), Positives = 116/271 (42%), Gaps = 39/271 (14%) Query: 37 PGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKD------WTR 90 PGG G N A +A +G G V+ + +++ +E + + R Sbjct: 50 PGGKGANQAVTVAKIG-----------EKGCRFVTCIGNDDYSDLLIENYEKLGITGYIR 98 Query: 91 QNL-----HVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLE---IESGAILVISGSLPP 142 +L + V+ +G+ + PGA +L++++++ + IL++ +P Sbjct: 99 VSLPTGRAFIEVDKTGQNRIIIFPGAN------AELKKELIDWNTLSESDILLLQNEIPF 152 Query: 143 GVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQP 202 LE A + GI + + ++ + ++ + PN+KE+ AL + Sbjct: 153 ETTLE------CAKRFNGIVIFDPAPAQGINEEI-FQYLDYLTPNEKEIEALSKDFFGEF 205 Query: 203 DDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAM 262 V KAA++ + G K V+V LG +G L V+ VK+ T AGD GA Sbjct: 206 LTVEKAAEKFLELG-VKNVIVKLGDKGVLLVNKNEKKHFPTFKVKAVDTTAAGDVFNGAF 264 Query: 263 TLKLAENASLEEMVRFGVAAGSAATLNQGTR 293 + L+E + EE V FG AA + + G + Sbjct: 265 AVALSEGKNPEEAVIFGTAAAAISVTRLGAQ 295 >6ILS-A nrPDB Length = 313 Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 8/193 (4%) Query: 95 VHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLIS 154 V +++ G+ ++ GA + ++ + + + I+++ +P + + Q+ Sbjct: 100 VMLQSDGQNSIIIVGGANMKAWPEIMSDDDLEIVRNAGIVLLQREIPDSINI----QVAK 155 Query: 155 AAQKQGIRCIVDSSG-EALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIV 213 A +K G+ I+D G + + +I+++ PN+ ELS L + + +A + Sbjct: 156 AVKKAGVPVILDVGGMDTPIPNELLDSIDILSPNETELSRLTGMPTETFEQISQAVAKCH 215 Query: 214 NSGKAKRVVVSLGPQG-ALGVDSENCIQ-VVPPPVKSQSTVGAGDSMVGAMTLKLAENAS 271 G K+V+V LG +G AL + E IQ + P + T GAGD+ A + + E S Sbjct: 216 KLG-VKQVLVKLGSKGSALFIQGEKPIQQSIIPAAQVVDTTGAGDTFTAAFAVAMVEGKS 274 Query: 272 LEEMVRFGVAAGS 284 EE +RF AA S Sbjct: 275 HEECLRFAAAAAS 287 >3KZH-A nrPDB Length = 328 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 9/123 (7%) Query: 178 IGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSEN 237 I + +KPN+ E L +T DD+ KA+ + G K+V +SL G D + Sbjct: 180 IKDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLGLG-IKKVFISLDADGIFYNDGVS 238 Query: 238 CIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSH 297 C ++ V ++ GAGDS V + +E++V+F A T++ T SH Sbjct: 239 CGKIKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIEDIVKF------AMTMSNIT--ISH 290 Query: 298 DDT 300 ++T Sbjct: 291 EET 293 >5EYN-A nrPDB Length = 323 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 84/312 (26%), Positives = 145/312 (46%), Gaps = 46/312 (14%) Query: 22 IYPEGK---LRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGAT--GEHLVSLLADE 76 + P+G+ L+C PGG NVA AIA L G +A F G G + L DE Sbjct: 31 LIPDGQQHYLKC------PGGAPANVAVAIARLSGR-SAFFGRVGNDPFGRFMQQTLTDE 83 Query: 77 NVPVATVEAKDWTRQN-LHVHVEASGEQ-YRFVMPGAALNEDEFRQLEEQVLEIESGAIL 134 V + R + + V ++ GE+ + F++ +A D+F QL + + + G L Sbjct: 84 QVDCQHLHFDPVHRTSTVVVDLDEHGERSFTFMVKPSA---DQFLQLSD-IPSFQKGEWL 139 Query: 135 VISGSLPPGVKLEKLTQLISAAQKQ----------GIRCIVDSSGEALSAAL--AIGNIE 182 + S+ + + + + AQ + +R V S + L A + A+G + Sbjct: 140 HVC-SIALANQPSRSSTFAAIAQMKEVGGYVSFDPNLREEVWSEPQELQATVMRAVGLAD 198 Query: 183 LVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVV 242 +VK +++EL + LT + + Q I + + VVV+LG +GAL V + N Q+V Sbjct: 199 VVKFSEEEL-----QFLTGTQSIEEGLQAIADF-QIPLVVVTLGAKGAL-VATPNSQQIV 251 Query: 243 P-PPVKSQSTVGAGDSMVGAMTLKLA------ENASLEEMVRFGVAAGSAATLNQGTRLC 295 VK T GAGD+ VG + +L+ A++ + V++ G+ AT +G + Sbjct: 252 SGKAVKPIDTTGAGDAFVGGLLYRLSVAQDWHNQATILDAVKWANGCGALATTQKGA-MT 310 Query: 296 SHDDTQKIYAYL 307 + + +YA+L Sbjct: 311 ALPNQAALYAFL 322 >5C40-A nrPDB Length = 330 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 64/261 (24%), Positives = 106/261 (40%), Gaps = 41/261 (15%) Query: 38 GGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA-TVEAKDWTRQNLHV 95 GG G N A LG + + G + G + L ++ T + KD + Sbjct: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111 Query: 96 HVEASGEQYRFVMPGAAL--NEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLI 153 V G+ ++ GA L N ++ R I ++V + P LE LT Sbjct: 112 IVNNEGQNIIVIVAGANLLLNTEDLRAAANV---ISRAKVMVCQLEITPATSLEALTM-- 166 Query: 154 SAAQKQGIRCIVDSSGEALSAALAIGNIE--------LVKPNQKELSALVNRELTQPDDV 205 A++ G++ + + A AI +++ + N+ E L + D Sbjct: 167 --ARRSGVKTL-------FNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADA 217 Query: 206 RKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPP-------VKSQSTVGAGDSM 258 +AA ++ G + V+++LG +G + + Q P P VK+ T GAGDS Sbjct: 218 GEAALVLLKRG-CQVVIITLGAEGCVVLS-----QTEPEPKHIPTEKVKAVDTTGAGDSF 271 Query: 259 VGAMTLKLAE--NASLEEMVR 277 VGA+ LA N SLE+M+ Sbjct: 272 VGALAFYLAYYPNLSLEDMLN 292 >2NWH-A nrPDB Length = 317 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 67/263 (25%), Positives = 112/263 (42%), Gaps = 40/263 (15%) Query: 36 EPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLAD----ENVPVATVEAK--DWT 89 E GGGG N AR ++ LG I P GG +V+ A E+ P ++ + +T Sbjct: 37 EAGGGGFNAARNLSRLGFEVRIIAPRGGDVTGEVVAEAARQAGVEDTPFTFLDRRTPSYT 96 Query: 90 ----RQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVK 145 R V A + Y+ P + R + E ++ + L+ +LP Sbjct: 97 AILERDGNLVIALADMDLYKLFTP----RRLKVRAVREAII---ASDFLLCDANLPE--- 146 Query: 146 LEKLTQ--LISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQ-- 201 + LT LI+ A ++ + I S +A+ A+G+I+++ N+ E AL Sbjct: 147 -DTLTALGLIARACEKPLAAIAISPAKAVKLKAALGDIDILFMNEAEARALTGETAENVR 205 Query: 202 --PDDVRKAAQE--IVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKS-QSTVGAGD 256 P+ +RKA +V G A VV G + A+ + PP ++ + GAGD Sbjct: 206 DWPNILRKAGLSGGVVTRG-ASEVVAFNGTEKAI---------LHPPLIREVKDVTGAGD 255 Query: 257 SMVGAMTLKLAENASLEEMVRFG 279 +M +AE ++ E +R G Sbjct: 256 AMASGYLAAIAEGKTIREALRQG 278 >3GBU-A nrPDB Length = 313 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 57/254 (22%), Positives = 111/254 (43%), Gaps = 35/254 (13%) Query: 25 EGKLRCTAPVFE--PGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVA 81 EG L+ +FE PGG NVA ++ LG ++ I G GE+L+ L+ ENV Sbjct: 19 EGDLK-DVRLFEKHPGGAPANVAVGVSRLGVKSSLISKVGNDPFGEYLIEELSKENVDTR 77 Query: 82 TVEAKDWTRQNLHVHVEASGEQYRFVMP------GAALNEDEFRQLEEQVLEIESGAILV 135 + KD + V V+ G F++ LN+ + +EE + + G++++ Sbjct: 78 GI-VKDEKKHTGIVFVQLKGASPSFLLYDDVAYFNMTLNDINWDIVEEAKI-VNFGSVIL 135 Query: 136 ISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALV 195 + +++ ++ I G +L A ++L + ++E+ ++ Sbjct: 136 AR----------------NPSRETVMKVIKKIKGSSLIAFDVNLRLDLWRGQEEEMIKVL 179 Query: 196 NRELTQPDDVRKAAQEIV---NSGKAKR----VVVSLGPQGALGVDSENCIQVVPPPVKS 248 + D V+ + +E++ N G + ++LGP+G + +E + V V Sbjct: 180 EESIKLADIVKASEEEVLYLENQGVEVKGSMLTAITLGPKGFRLIKNETVVDVPSYNVNP 239 Query: 249 QSTVGAGDSMVGAM 262 T GAGD+ + A+ Sbjct: 240 LDTTGAGDAFMAAL 253 >1TYY-A nrPDB Length = 339 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 76/291 (26%), Positives = 109/291 (37%), Gaps = 63/291 (21%) Query: 37 PGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAK-DWTRQNLH 94 PGG NV +A LGG I G G L + D V V + D T L Sbjct: 49 PGGASANVGVCVARLGGECGFIGCLGDDDAGRFLRQVFQDNGVDVTFLRLDADLTSAVLI 108 Query: 95 VHVEASGEQ--YRFVMPGAAL-----NEDEFRQLE---------------EQVLE----- 127 V++ A GE+ V PGA + FRQ E E LE Sbjct: 109 VNLTADGERSFTYLVHPGADTYVSPQDLPPFRQYEWFYFSSIGLTDRPAREACLEGARRM 168 Query: 128 IESGAILVISGSLPPGV--KLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVK 185 E+G ++ +L + +++ +LI A SAALA + K Sbjct: 169 REAGGYVLFDVNLRSKMWGNTDEIPELI-----------------ARSAALA----SICK 207 Query: 186 PNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPP 245 + EL L Q D R +++ ++SLG GAL + +E P Sbjct: 208 VSADELCQLSGASHWQ--DARYYLRDL----GCDTTIISLGADGALLITAEGEFHFPAPR 261 Query: 246 VKSQSTVGAGDSMVGAMTLKLA-----ENASLEEMVRFGVAAGSAATLNQG 291 V T GAGD+ VG + L+ ++A L E + A G+ A +G Sbjct: 262 VDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEAISNANACGAMAVTAKG 312 >3RY7-A nrPDB Length = 304 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 2/114 (1%) Query: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ 240 I+++ PN+ E L ++T ++ A ++ G K V+++LG QG Sbjct: 180 IDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIG-IKTVLITLGKQGTYFATKNQSQH 238 Query: 241 VVPPPVKSQSTVGAGDSMVGAMTLKLAENA-SLEEMVRFGVAAGSAATLNQGTR 293 + V + T AGD+ +GA +L ++ +L + + FG A S G + Sbjct: 239 IEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQ 292 >3PL2-A nrPDB Length = 319 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 6/104 (5%) Query: 200 TQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMV 259 T+P+ +A + ++ G + +V GP+G + + + ++V P V + +GAGD+ Sbjct: 213 TEPE---RAGRALLERG-VELAIVKQGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFG 268 Query: 260 GAMTLKLAENASLEEMVRFGVAAGS--AATLNQGTRLCSHDDTQ 301 GA+ L LE+++RF AG+ A+ L T + + D+ + Sbjct: 269 GALCHGLLSEWPLEKVLRFANTAGALVASRLECSTAMPTTDEVE 312 >5ZWY-A nrPDB Length = 349 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 6/117 (5%) Query: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENC-- 238 + L PN+ E + + ++T + A + + G + VV++LG G V SEN Sbjct: 223 VSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLG-VRDVVITLGAAGF--VLSENGAE 279 Query: 239 -IQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRL 294 + V VK+ T GAGD VG+M ++ +L E + + + +GT+L Sbjct: 280 PVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQL 336 >1RK2-A nrPDB Length = 309 Score = 37.0 bits (84), Expect = 0.010, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 50/96 (52%), Gaps = 5/96 (5%) Query: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALG-VDSENCI 239 ++++ PN+ E L + +D KAAQ +++ + V+++LG +G V+ E Sbjct: 181 VDIITPNETEAEKLTGIRVENDEDAAKAAQ-VLHEKGIRTVLITLGSRGVWASVNGEG-- 237 Query: 240 QVVPP-PVKSQSTVGAGDSMVGAMTLKLAENASLEE 274 Q VP V++ T+ AGD+ GA+ L E L E Sbjct: 238 QRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPE 273 >3H49-A nrPDB Length = 325 Score = 35.4 bits (80), Expect = 0.029, Method: Compositional matrix adjust. Identities = 65/276 (23%), Positives = 112/276 (40%), Gaps = 43/276 (15%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGG--ATGEHLVSLLADENVPVATVEAKDWTRQNLHV 95 GG IN A I+ LG TA+ G A G+ ++ EN+ + +++ +++V Sbjct: 43 GGDAINEATIISRLG-HRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINV 101 Query: 96 HVEASGEQYRFVMPGAA----LNEDEF---RQLEEQVLEIESGAILVISGSLPPGVKLEK 148 + + FV LN D+ R + ++L + S + + L G + Sbjct: 102 GLVTEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLAS----IFNSPLLDG---KA 154 Query: 149 LTQLISAAQ-KQGIRC----------IVDSSGEALSAALAIGNIELVKPNQKELSALVNR 197 LT++ + A+ +Q I C +D EALS ++ + PN E L + Sbjct: 155 LTEIFTQAKARQMIICADMIKPRLNETLDDICEALSY------VDYLFPNFAEAKLLTGK 208 Query: 198 ELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPP--VKSQSTVGAG 255 E + + A + G K VV+ G G + + VP + + T+GAG Sbjct: 209 ET-----LDEIADCFLACG-VKTVVIKTGKDGCF-IKRGDMTMKVPAVAGITAIDTIGAG 261 Query: 256 DSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQG 291 D+ L E +L E RF A + + L+ G Sbjct: 262 DNFASGFIAALLEGKNLRECARFANATAAISVLSVG 297 >4X8F-A nrPDB Length = 309 Score = 34.7 bits (78), Expect = 0.049, Method: Compositional matrix adjust. Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Query: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ 240 ++L+ PN+ E L + ++AA + G + V+++LG +G + + Sbjct: 181 VDLITPNETEAEVLTGITVYDDSSAQQAADALHCKG-IEIVIITLGSKGVWLSQNGRGQR 239 Query: 241 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRF 278 + VK+ T AGD+ GA+ L + LE ++F Sbjct: 240 IPGFVVKATDTTAAGDTFNGALVTGLLQEMPLESAIKF 277 >2HW1-A nrPDB Length = 298 Score = 34.7 bits (78), Expect = 0.058, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 8/75 (10%) Query: 205 VRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTL 264 VRK A ++ A+ +LGP G L + S+ PPP + T+GAGD+ ++ Sbjct: 215 VRKGA--VLVCAWAEEGADALGPDGKL-LHSD----AFPPP-RVVDTLGAGDTFNASVIF 266 Query: 265 KLAENASLEEMVRFG 279 L++ S++E +RFG Sbjct: 267 SLSQGRSVQEALRFG 281 >3NCA-A nrPDB Length = 313 Score = 34.7 bits (78), Expect = 0.060, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 8/75 (10%) Query: 205 VRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTL 264 VRK A ++ A+ +LGP G L + S+ PPP + T+GAGD+ ++ Sbjct: 230 VRKGA--VLVCAWAEEGADALGPDGKL-LHSD----AFPPP-RVVDTLGAGDTFNASVIF 281 Query: 265 KLAENASLEEMVRFG 279 L++ S++E +RFG Sbjct: 282 SLSQGRSVQEALRFG 296 >3GO6-A nrPDB Length = 310 Score = 34.3 bits (77), Expect = 0.065, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 222 VVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAEN----ASLEEMVR 277 V++LG +GA V ++ +V P V T GAGD G + N A +R Sbjct: 214 VITLGVRGARYVGADGVFEVPAPTVTPVDTAGAGDVFAGVLAANWPRNPGSPAERLRALR 273 Query: 278 FGVAAGSAATLNQGTRLC 295 AAG+ ATL G C Sbjct: 274 RACAAGALATLVSGVGDC 291 >3HJ6-A nrPDB Length = 327 Score = 33.9 bits (76), Expect = 0.098, Method: Compositional matrix adjust. Identities = 52/255 (20%), Positives = 103/255 (40%), Gaps = 23/255 (9%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGG-ATGEHLVSLLADENVPVATVEAKDWTRQNLHVH 96 GG N+A ++ LG I G A G +L+ +L E + ++ +D R+ V+ Sbjct: 54 GGSPANIAVNLSRLGKKVALISRLGADAFGNYLLDVLKGEQIITDGIQ-QDKERRTTIVY 112 Query: 97 VEASGEQYRFVMPGAALNEDEFRQLEEQVLEI--ESGAILVISGSLPPGVKLEKLTQLIS 154 V S ++ A D + Q ++ + E+ S + + L + + + Sbjct: 113 VSKSTRTPDWLPYREA---DMYLQEDDIIFELIKRSKVFHLSTFILSRKPARDTAIKAFN 169 Query: 155 AAQKQG--------IRCIVDSSGEALSAALA--IGNIELVKPNQKELSALVNRELTQPDD 204 A++QG R ++ G+ + + I + VKP+ + R L PD Sbjct: 170 YAREQGKIVCFDPCYRKVLWPEGDDGAGVVEEIISRADFVKPSLDD-----ARHLFGPDS 224 Query: 205 VRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTL 264 + + G K V+++LG +G + D E I++ + GAGD+ Sbjct: 225 PENYVKRYLELG-VKAVILTLGEEGVIASDGEEIIRIPAFSEDAVDVTGAGDAFWSGFIC 283 Query: 265 KLAENASLEEMVRFG 279 L + +++ ++ G Sbjct: 284 GLLDGYTVKRSIKLG 298 >4WB0-B nrPDB Length = 414 Score = 32.0 bits (71), Expect = 0.38, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 29/65 (44%) Query: 174 AALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGV 233 A L + N EL K + ELSA+ R T V + G+ + V+ +G LG+ Sbjct: 307 AHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQTPGRWEHVINQIGMFSFLGL 366 Query: 234 DSENC 238 E C Sbjct: 367 SKEQC 371 >1TD2-A nrPDB Length = 287 Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust. Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 9/110 (8%) Query: 182 ELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQG-------ALGVD 234 +++ PN EL L + ++ AA+E++ G +V L G L V Sbjct: 141 DIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVT 200 Query: 235 SENCIQVVPPPVK--SQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAA 282 ++ + P V + VG GD G + +KL + A+L+E + AA Sbjct: 201 ADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQEALEHVTAA 250 >3A42-A nrPDB Length = 295 Score = 30.8 bits (68), Expect = 0.71, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 21/40 (52%) Query: 184 VKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVV 223 + P +KE LV R+ P+ + A +I+ SGK KR Sbjct: 241 IHPTEKEFDFLVYRKKKDPNGNKVIADKIIGSGKNKRTTY 280 >5XV0-A nrPDB Length = 240 Score = 30.8 bits (68), Expect = 0.81, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 39/87 (44%), Gaps = 12/87 (13%) Query: 90 RQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKL 149 R L+ + GE R + + E++ R LEE+ L I++GA V L Sbjct: 103 RTPLNADIFKKGEGLRIIAVSNSAPEEKIRMLEEKALVIKTGAFRV------------DL 150 Query: 150 TQLISAAQKQGIRCIVDSSGEALSAAL 176 T+L + ++ GI ++ G L+ + Sbjct: 151 TELAAKLKEMGINSLMVEGGATLNWGM 177 >3L73-B nrPDB Length = 441 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 22/44 (50%) Query: 89 TRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGA 132 T + LH V+ + R + G + + +Q+ EQ L I SGA Sbjct: 189 TSEQLHHFVQNNFTSARMALVGIGVKHSDLKQVAEQFLNIRSGA 232 >3RC8-A nrPDB Length = 677 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 5/112 (4%) Query: 83 VEAKDWTRQNLHVHVEASGEQYRFVMPG---AALNEDEFRQLEEQVLEIESGAILVISGS 139 VE +D+ R ++ + E + PG ++++ + Q+ EI VI GS Sbjct: 295 VEVRDYKRLTPISVLDHALESLDNLRPGDCIVCFSKNDIYSVSRQI-EIRGLESAVIYGS 353 Query: 140 LPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAAL-AIGNIELVKPNQKE 190 LPPG KL + + I D+ G L+ ++ I L+KP+ E Sbjct: 354 LPPGTKLAQAKKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINE 405 >3KTN-A nrPDB Length = 346 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 23/47 (48%) Query: 245 PVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQG 291 P+ + +GAGD+ + ++N SLE+ V F G A QG Sbjct: 269 PLLNLDRIGAGDAYAAGILYGYSQNWSLEKAVTFATVNGVLAHTIQG 315 >2QI2-A nrPDB Length = 347 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 5/53 (9%) Query: 66 GEHL-VSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDE 117 G+H +++ D + + K+W Q++ + EA+ E+Y V A++EDE Sbjct: 94 GKHQSITVTVDSEISIT----KEWDDQHIDLLKEATDEKYVTVYTAVAMDEDE 142 >2VAR-A nrPDB Length = 313 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 25/120 (20%), Positives = 53/120 (44%), Gaps = 6/120 (5%) Query: 165 VDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVS 224 ++ + E + + L +IE++ + + L+ ++T PD+ + +E+ K ++ Sbjct: 173 LEKAKETILSILKKYDIEVLITDPDDTKILL--DVTDPDEAYRKYKEL----GVKVLLYK 226 Query: 225 LGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGS 284 LG +GA+ V + GAGD+M G + +E + G+AA + Sbjct: 227 LGSKGAIAYKDNVKAFKDAYKVPVEDPTGAGDAMAGTFVSLYLQGKDIEYSLAHGIAAST 286 >4N08-A nrPDB Length = 348 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 8/89 (8%) Query: 182 ELVKPNQKELSALVNRELTQPDDV----RKAAQEIVNSGKAKRVVVSLGPQGALGVDSEN 237 +++ N+ E N D V R+A E+ +G RVVV + + +++ Sbjct: 220 DIIVANRHEAKEFANMMKWDTDCVEEIARRAVSEVPYTGTKGRVVVFTRDIESTVLATKD 279 Query: 238 CIQVVPPPVKSQSTV----GAGDSMVGAM 262 ++ VP P Q V GAGD+ +G Sbjct: 280 GVETVPVPQLDQDKVIDMNGAGDAFMGGF 308 >2O1M-A nrPDB Length = 258 Score = 28.5 bits (62), Expect = 4.1, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 3/45 (6%) Query: 177 AIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRV 221 +GN V N K E T DD+ KA QEI++ G KR+ Sbjct: 195 TVGN---VLSNAKVYFMFNKNEQTLSDDIDKALQEIIDDGTLKRL 236 >4MKS-A nrPDB Length = 440 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 16/31 (51%) Query: 45 ARAIAHLGGSATAIFPAGGATGEHLVSLLAD 75 A LGG AI P+G +TGEH L D Sbjct: 23 AEVYTELGGFGRAIVPSGASTGEHEAVELRD 53 >4DU5-A nrPDB Length = 336 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 7/106 (6%) Query: 182 ELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQV 241 + V P +E L T P+ V + +++ AK VVV LG +GA +V Sbjct: 216 DWVLPGMEEGRFLTGE--TTPEGVARFYRQL----GAKLVVVKLGAEGAYFDGEAGSGRV 269 Query: 242 VPPPV-KSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAA 286 PV + TVGAGD + L + + E V+ G G+ A Sbjct: 270 AGFPVAEVVDTVGAGDGFAVGVISALLDGLGVPEAVKRGAWIGARA 315 >4LC4-A nrPDB Length = 352 Score = 28.1 bits (61), Expect = 5.5, Method: Compositional matrix adjust. Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 10/123 (8%) Query: 163 CIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVV 222 C+ GE L + G +++V N++E AL L Q DD +A I + K Sbjct: 214 CVDRYRGEFLDL-MRSGKVDIVFANRQE--AL---SLYQTDDFEEALNRI--AADCKIAA 265 Query: 223 VSLGPQGALGVDSENCIQVVPPPVKSQ-STVGAGDSMVGAMTLKLAENASLEEMVRFG-V 280 V++ GA+ + V ++ T GAGD + SLE+ + G + Sbjct: 266 VTMSENGAVILKGRERYYVNAIRIREVVDTTGAGDLFASGFLYGYTQGRSLEDCGKLGCL 325 Query: 281 AAG 283 AAG Sbjct: 326 AAG 328 >3PB0-A nrPDB Length = 300 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 113 LNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQG 160 +NEDE +L + LEI G I VI G+ EK +L+ A+K G Sbjct: 56 VNEDEREKLVSRTLEIVDGKIPVIVGAGTNST--EKTLKLVKQAEKLG 101 >3IQ0-A nrPDB Length = 330 Score = 27.7 bits (60), Expect = 7.4, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 28/73 (38%) Query: 219 KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRF 278 K V+V G QGA + V PV+ GAGD GA +++ Sbjct: 223 KEVIVKRGNQGASYYSANEQFHVESYPVEEVDPTGAGDCFGGAWIACRQLGFDAHRALQY 282 Query: 279 GVAAGSAATLNQG 291 A G+ A +G Sbjct: 283 ANACGALAVTRRG 295 >3LU2-A nrPDB Length = 311 Score = 27.3 bits (59), Expect = 9.2, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 123 EQVLEIESGAILVISGSLPPGVKLEKLTQLIS 154 E + E + GA+L + G P G L+KLTQL+ Sbjct: 94 ENLPEDKIGAMLTLEGIEPIGRDLDKLTQLLD 125 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3N1C-A nrPDB 352 9e-98 2AWD-A nrPDB 294 3e-80 2ABQ-A nrPDB 285 1e-77 2JG5-A nrPDB 278 3e-75 2AJR-A nrPDB 271 2e-73 2Q5R-A nrPDB 271 3e-73 3JUL-A nrPDB 256 9e-69 5EYN-A nrPDB 196 1e-50 1VM7-A nrPDB 189 1e-48 6ILS-A nrPDB 186 1e-47 1TYY-A nrPDB 175 2e-44 5C40-A nrPDB 172 1e-43 3GBU-A nrPDB 159 1e-39 3RY7-A nrPDB 155 2e-38 2NWH-A nrPDB 143 1e-34 3KZH-A nrPDB 137 5e-33 3PL2-A nrPDB 117 7e-27 Sequences not found previously or not previously below threshold: 5ZWY-A nrPDB 141 3e-34 4X8F-A nrPDB 134 6e-32 1RK2-A nrPDB 132 2e-31 3HJ6-A nrPDB 116 1e-26 3H49-A nrPDB 115 3e-26 1V1S-A nrPDB 101 6e-22 3IQ0-A nrPDB 100 7e-22 2C4E-A nrPDB 98 3e-21 3I3Y-A nrPDB 98 5e-21 2QCV-A nrPDB 97 1e-20 6CW5-A nrPDB 95 4e-20 4E84-A nrPDB 89 2e-18 3LJS-A nrPDB 89 2e-18 3NCA-A nrPDB 88 3e-18 2QHP-A nrPDB 88 4e-18 5KB6-A nrPDB 85 5e-17 2I6B-A nrPDB 84 9e-17 4DU5-A nrPDB 83 1e-16 1WYE-A nrPDB 83 2e-16 4WJM-A nrPDB 83 2e-16 3KD6-A nrPDB 81 7e-16 2HW1-A nrPDB 81 8e-16 4N08-A nrPDB 80 1e-15 3UBO-A nrPDB 79 2e-15 2RBC-A nrPDB 78 6e-15 4LC4-A nrPDB 77 9e-15 6C9R-A nrPDB 76 1e-14 3B1N-A nrPDB 74 5e-14 3GO6-A nrPDB 73 2e-13 3LOO-A nrPDB 72 4e-13 2VAR-A nrPDB 72 4e-13 4GM6-A nrPDB 68 5e-12 2AFB-A nrPDB 66 2e-11 3LHX-A nrPDB 65 4e-11 3BF5-A nrPDB 63 2e-10 2AA0-A nrPDB 61 9e-10 3KTN-A nrPDB 60 1e-09 1TD2-A nrPDB 59 2e-09 3UQ9-A nrPDB 57 9e-09 3PZS-A nrPDB 57 1e-08 4C5N-A nrPDB 53 1e-07 4JJP-A nrPDB 53 2e-07 2I5B-A nrPDB 52 3e-07 5YSQ-A nrPDB 51 5e-07 4S1M-A nrPDB 49 2e-06 1JXH-A nrPDB 48 4e-06 5B6A-A nrPDB 48 5e-06 2DDM-A nrPDB 48 7e-06 4XF7-A nrPDB 43 2e-04 1UB0-A nrPDB 43 2e-04 1YGJ-A nrPDB 42 3e-04 5TRW-A nrPDB 41 5e-04 4E69-A nrPDB 41 8e-04 5ZWB-B nrPDB 39 0.002 3MBJ-A nrPDB 39 0.003 5TQI-A nrPDB 38 0.005 2F7K-A nrPDB 37 0.009 3ZS7-A nrPDB 35 0.051 3HYO-A nrPDB 32 0.30 1J3W-A nrPDB 31 0.47 3RMJ-A nrPDB 31 0.48 5EIY-B nrPDB 31 0.74 3IC9-A nrPDB 30 1.1 4YL5-A nrPDB 30 1.5 5JFQ-A nrPDB 29 2.3 4BJP-A nrPDB 29 3.0 4KXX-A nrPDB 28 6.1 4PR3-A nrPDB 27 8.8 >3N1C-A nrPDB Length = 309 Score = 352 bits (903), Expect = 9e-98, Method: Composition-based stats. Identities = 309/309 (100%), Positives = 309/309 (100%) Query: 1 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP 60 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP Sbjct: 1 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP 60 Query: 61 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ 120 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ Sbjct: 61 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ 120 Query: 121 LEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN 180 LEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN Sbjct: 121 LEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN 180 Query: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ 240 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ Sbjct: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ 240 Query: 241 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDT 300 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDT Sbjct: 241 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDT 300 Query: 301 QKIYAYLSR 309 QKIYAYLSR Sbjct: 301 QKIYAYLSR 309 >2AWD-A nrPDB Length = 323 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 88/311 (28%), Positives = 159/311 (51%), Gaps = 10/311 (3%) Query: 1 MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFP 60 M I T+T+ PS+D + + + + R + PGG G+NV R I LGG A Sbjct: 1 MSLIVTVTMNPSIDISYLLDHLKLDTVNRTSQVTKTPGGKGLNVTRVIHDLGGDVIATGV 60 Query: 61 AGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ 120 GG G + + L N+P A K+ TR ++ + E G Q + G ++ +E Sbjct: 61 LGGFHGAFIANELKKANIPQAFTSIKEETRDSIAILHE--GNQTEILEAGPTVSPEEISN 118 Query: 121 LEEQVLE-IESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAAL-AI 178 E + I+ I+ ISGSL G+ + +L+ A Q ++ ++D+SG++L L Sbjct: 119 FLENFDQLIKQAEIVTISGSLAKGLPSDFYQELVQKAHAQEVKVLLDTSGDSLRQVLQGP 178 Query: 179 GNIELVKPNQKELSALVNRELTQPD--DVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSE 236 L+KPN +EL L+ ++ ++ V+ A + + +G + +V+SLG GA+ + Sbjct: 179 WKPYLIKPNLEELEGLLGQDFSENPLAAVQTALTKPMFAG-IEWIVISLGKDGAIAKHHD 237 Query: 237 NCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCS 296 +V P +++++ VG+GD+ + + LA++A E++++G+AAG A N R+ Sbjct: 238 QFYRVKIPTIQAKNPVGSGDATIAGLAYGLAKDAPAAELLKWGMAAGMA---NAQERMTG 294 Query: 297 HDDTQKIYAYL 307 H D + + +L Sbjct: 295 HVDVENVKKHL 305 >2ABQ-A nrPDB Length = 306 Score = 285 bits (730), Expect = 1e-77, Method: Composition-based stats. Identities = 101/308 (32%), Positives = 157/308 (50%), Gaps = 9/308 (2%) Query: 3 RIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG 62 IYT+TL PS+D R +PGG GINV+R + LG A+ G Sbjct: 1 MIYTVTLNPSIDYIVQVENFQQGVVNRSERDRKQPGGKGINVSRVLKRLGHETKALGFLG 60 Query: 63 GATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQ-L 121 G TG ++ + L E + ++ +E + TR ++V+ G+Q + A L + E Q L Sbjct: 61 GFTGAYVRNALEKEEIGLSFIEVEGDTR----INVKIKGKQETELNGTAPLIKKEHVQAL 116 Query: 122 EEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNI 181 EQ+ E+E G +LV++GS+P + + A+++G VD+SGEAL LA Sbjct: 117 LEQLTELEKGDVLVLAGSVPQAMPQTIYRSMTQIAKERGAFVAVDTSGEALHEVLA-AKP 175 Query: 182 ELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQV 241 +KPN ELS LV++ + +D Q ++ G + ++VS GAL +E V Sbjct: 176 SFIKPNHHELSELVSKPIASIEDAIPHVQRLIGEG-IESILVSFAGDGALFASAEGMFHV 234 Query: 242 VPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQ 301 P + +++VGAGDS+V L E SLE+ V F VAAGSA + G C+ ++ + Sbjct: 235 NVPSGEVRNSVGAGDSVVAGFLAALQEGKSLEDAVPFAVAAGSATAFSDG--FCTREEVE 292 Query: 302 KIYAYLSR 309 ++ L R Sbjct: 293 RLQQQLQR 300 >2JG5-A nrPDB Length = 306 Score = 278 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 93/306 (30%), Positives = 155/306 (50%), Gaps = 7/306 (2%) Query: 3 RIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG 62 IYT+T PS+D T +G R TA GG GINV+R + L +TA+ AG Sbjct: 1 MIYTVTFNPSIDYVIFTNDFKIDGLNRATATYKFAGGKGINVSRVLKTLDVESTALGFAG 60 Query: 63 GATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLE 122 G G+ ++ L + + +E + TR N+ + +G++ PG + +F QL Sbjct: 61 GFPGKFIIDTLNNSAIQSNFIEVDEDTRINVKL---KTGQETEINAPGPHITSTQFEQLL 117 Query: 123 EQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIE 182 +Q+ S I++++GS+P + + Q+ + G + +VD+ E + L + Sbjct: 118 QQIKNTTSEDIVIVAGSVPSSIPSDAYAQIAQITAQTGAKLVVDAEKELAESVLPYHPL- 176 Query: 183 LVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVV 242 +KPN+ EL + N + DV K + +V+ G A+ V+VSLG GA+ +D E I+ V Sbjct: 177 FIKPNKDELEVMFNTTVNSDADVIKYGRLLVDKG-AQSVIVSLGGDGAIYIDKEISIKAV 235 Query: 243 PPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQK 302 P K +TVG+GDS V M +A S+E+ + VA G+A + L + D +K Sbjct: 236 NPQGKVVNTVGSGDSTVAGMVAGIASGLSIEKAFQQAVACGTATAFD--EDLATRDAIEK 293 Query: 303 IYAYLS 308 I + ++ Sbjct: 294 IKSQVT 299 >2AJR-A nrPDB Length = 331 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 79/318 (24%), Positives = 141/318 (44%), Gaps = 16/318 (5%) Query: 3 RIYTLTLAPSLDSATIT-----PQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATA 57 + T+TL P+LD ++Y L T PGG GINV+ A++ LG + A Sbjct: 13 MVLTVTLNPALDREIFIEDFQVNRLYRINDLSKTQ--MSPGGKGINVSIALSKLGVPSVA 70 Query: 58 IFPAGGATGEHLVSLLADEN--VPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNE 115 GG G+ LV L + + V + TR+N+ + E + PG + + Sbjct: 71 TGFVGGYMGKILVEELRKISKLITTNFVYVEGETRENIEIIDEKNKTITAINFPGPDVTD 130 Query: 116 -DEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSA 174 D L + + +VISGS+PPGV +L+ A+++G+ V+ + L Sbjct: 131 MDVNHFLRRYKMTLSKVDCVVISGSIPPGVNEGICNELVRLARERGVFVFVEQTPRLLER 190 Query: 175 ALAIGN-IELVKPNQK-ELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALG 232 +VKP+ + ++ + +L DD K A+++ + K++ VVS + + Sbjct: 191 IYEGPEFPNVVKPDLRGNHASFLGVDLKTFDDYVKLAEKL--AEKSQVSVVSYEVKNDIV 248 Query: 233 VDSENCIQV-VPPPVKSQSTVGAGDSMVGAMTLKLAEN-ASLEEMVRFGVAAGSAATLNQ 290 E + + + +GAGD+ V M ++ A+ EM +FG A+ AAT + Sbjct: 249 ATREGVWLIRSKEEIDTSHLLGAGDAYVAGMVYYFIKHGANFLEMAKFGFASALAATRRK 308 Query: 291 GTRLCSHDDTQKIYAYLS 308 + + +K Y + + Sbjct: 309 EKYMPDLEAIKKEYDHFT 326 >2Q5R-A nrPDB Length = 330 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 80/311 (25%), Positives = 140/311 (45%), Gaps = 10/311 (3%) Query: 3 RIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG 62 I TLTL PS+D + + + R GG G+NV R +A +G A G Sbjct: 21 MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIG 80 Query: 63 GATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDE---FR 119 G G+ + L ++ A K TR + + E G+Q + G ++ E F Sbjct: 81 GELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHE--GQQTEILEQGPEIDNQEAAGFI 138 Query: 120 QLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIG 179 + EQ+ +E + ISGSLP G+ + Q+I Q +G+ I+D SG L L Sbjct: 139 KHFEQL--LEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENP 196 Query: 180 -NIELVKPNQKELSALVNRELTQP-DDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSEN 237 ++KPN EL L+N+ L + + +++A + + G + ++VSLG QGA + Sbjct: 197 YKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEG-IEWIIVSLGAQGAFAKHNHT 255 Query: 238 CIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSH 297 +V P + + VG+GDS V +T + + + ++++ G T + Sbjct: 256 FYRVNIPTISVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNL 315 Query: 298 DDTQKIYAYLS 308 ++ ++ + Sbjct: 316 NNYDDLFNQIE 326 >3JUL-A nrPDB Length = 320 Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats. Identities = 77/312 (24%), Positives = 150/312 (48%), Gaps = 11/312 (3%) Query: 1 MVRIYTLTLAPSLDSATI-TPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIF 59 M IYT+TL P++D ++ R F+ GG G++V+ ++ G A+ Sbjct: 1 MSLIYTITLNPAIDRLLFIRGELEKRKTNRVIKTEFDCGGKGLHVSGVLSKFGIKNEALG 60 Query: 60 PAGGATGEHLVSLLADENVPVAT-VEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEF 118 AG + L ++L ++++ VEA TR+ V + + G +++ Sbjct: 61 IAGSDNLDKLYAILKEKHINHDFLVEAGTSTRECFVVLSDDTNGSTMIPEAGFTVSQTNK 120 Query: 119 RQLEEQV-LEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALA 177 L +Q+ +++ ++VI+GS PP L +L+ + G D+SGE L+ A+ Sbjct: 121 DNLLKQIAKKVKKEDMVVIAGSPPPHYTLSDFKELLRTVKATGAFLGCDNSGEYLNLAVE 180 Query: 178 IGNIELVKPNQKELSALVNRELTQ-PDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSE 236 +G ++ +KPN+ E+ A+++ + +++R A++ +VVSLG +G++ + Sbjct: 181 MG-VDFIKPNEDEVIAILDEKTNSLEENIRTLAEK------IPYLVVSLGAKGSICAHNG 233 Query: 237 NCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCS 296 QV+PP V+ ++ GAGD VGA LA N + E ++ ++ + Q + Sbjct: 234 KLYQVIPPKVQERNDTGAGDVFVGAFIAGLAMNMPITETLKVATGCSASKVMQQDSSSFD 293 Query: 297 HDDTQKIYAYLS 308 + K+ +S Sbjct: 294 LEAAGKLKNQVS 305 >5EYN-A nrPDB Length = 323 Score = 196 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 75/310 (24%), Positives = 131/310 (42%), Gaps = 34/310 (10%) Query: 19 TPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADEN 77 + P+G+ + PGG NVA AIA L G + G G + L DE Sbjct: 28 VVDLIPDGQ---QHYLKCPGGAPANVAVAIARLSGRSAFFGRVGNDPFGRFMQQTLTDEQ 84 Query: 78 VPVATVEAKDWTRQN-LHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVI 136 V + R + + V ++ GE+ M + D+F QL + + + G L + Sbjct: 85 VDCQHLHFDPVHRTSTVVVDLDEHGERSFTFMVKP--SADQFLQLSD-IPSFQKGEWLHV 141 Query: 137 SGSLPPGVKLEKLTQLISAAQKQGI----------RCIVDSSGEALSAAL--AIGNIELV 184 S+ + + + + AQ + + R V S + L A + A+G ++V Sbjct: 142 C-SIALANQPSRSSTFAAIAQMKEVGGYVSFDPNLREEVWSEPQELQATVMRAVGLADVV 200 Query: 185 KPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPP 244 K +++EL L + + Q I + + VVV+LG +GAL + V Sbjct: 201 KFSEEELQFLTG-----TQSIEEGLQAIADF-QIPLVVVTLGAKGALVATPNSQQIVSGK 254 Query: 245 PVKSQSTVGAGDSMVGAMTLKLA------ENASLEEMVRFGVAAGSAATLNQGTRLCSHD 298 VK T GAGD+ VG + +L+ A++ + V++ G+ AT +G + + Sbjct: 255 AVKPIDTTGAGDAFVGGLLYRLSVAQDWHNQATILDAVKWANGCGALATTQKGA-MTALP 313 Query: 299 DTQKIYAYLS 308 + +YA+L Sbjct: 314 NQAALYAFLE 323 >1VM7-A nrPDB Length = 311 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 67/321 (20%), Positives = 125/321 (38%), Gaps = 36/321 (11%) Query: 1 MVRIYTLTLAPSLDSATITPQI-YPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIF 59 M + ++ + ++D P + PGG G N A +A +G Sbjct: 13 MFLVISVVGSSNIDIVLKVDHFTKPGETQKAIEMNVFPGGKGANQAVTVAKIG------- 65 Query: 60 PAGGATGEHLVSLLADENVPVATVEAKD------WTRQNL-----HVHVEASGEQYRFVM 108 G V+ + +++ +E + + R +L + V+ +G+ + Sbjct: 66 ----EKGCRFVTCIGNDDYSDLLIENYEKLGITGYIRVSLPTGRAFIEVDKTGQNRIIIF 121 Query: 109 PGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSS 168 PGA + + IL++ +P LE A + GI + Sbjct: 122 PGANAELKKELI---DWNTLSESDILLLQNEIPFETTLE------CAKRFNGIVIFDPAP 172 Query: 169 GEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQ 228 + ++ + ++ + PN+KE+ AL + V KAA++ + G K V+V LG + Sbjct: 173 AQGINEEI-FQYLDYLTPNEKEIEALSKDFFGEFLTVEKAAEKFLELG-VKNVIVKLGDK 230 Query: 229 GALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATL 288 G L V+ VK+ T AGD GA + L+E + EE V FG AA + + Sbjct: 231 GVLLVNKNEKKHFPTFKVKAVDTTAAGDVFNGAFAVALSEGKNPEEAVIFGTAAAAISVT 290 Query: 289 NQGTR--LCSHDDTQKIYAYL 307 G + + + ++ + L Sbjct: 291 RLGAQSSIPAREEVEAFLKNL 311 >6ILS-A nrPDB Length = 313 Score = 186 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 66/303 (21%), Positives = 122/303 (40%), Gaps = 15/303 (4%) Query: 14 DSATITPQIYPEGKLRCTAPVFE-PGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVS 71 D ++ EG+ GG G N A A L + G G+ + Sbjct: 14 DIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGEDAHGKLIAE 73 Query: 72 LLADENVPVATVEAKD---WTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEI 128 L D+ V + + V +++ G+ ++ GA + ++ + + Sbjct: 74 ALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEIMSDDDLEIV 133 Query: 129 ESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSG-EALSAALAIGNIELVKPN 187 + I+++ +P + + Q+ A +K G+ I+D G + + +I+++ PN Sbjct: 134 RNAGIVLLQREIPDSINI----QVAKAVKKAGVPVILDVGGMDTPIPNELLDSIDILSPN 189 Query: 188 QKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQG-ALGVDSENCIQ-VVPPP 245 + ELS L + + +A + G K+V+V LG +G AL + E IQ + P Sbjct: 190 ETELSRLTGMPTETFEQISQAVAKCHKLG-VKQVLVKLGSKGSALFIQGEKPIQQSIIPA 248 Query: 246 VKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGT--RLCSHDDTQKI 303 + T GAGD+ A + + E S EE +RF AA S +G + K+ Sbjct: 249 AQVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPSMPDRKSVLKL 308 Query: 304 YAY 306 + Sbjct: 309 LKF 311 >1TYY-A nrPDB Length = 339 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 72/324 (22%), Positives = 115/324 (35%), Gaps = 67/324 (20%) Query: 21 QIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGAT-GEHLVSLLADENVP 79 + PE + + PGG NV +A LGG I G G L + D V Sbjct: 36 DLVPEKQNS---YLKCPGGASANVGVCVARLGGECGFIGCLGDDDAGRFLRQVFQDNGVD 92 Query: 80 VATVEAK-DWTRQNLHVHVEASGEQ--YRFVMPGAAL-----NEDEFRQL---------- 121 V + D T L V++ A GE+ V PGA + FRQ Sbjct: 93 VTFLRLDADLTSAVLIVNLTADGERSFTYLVHPGADTYVSPQDLPPFRQYEWFYFSSIGL 152 Query: 122 -----EEQVLE-----IESGAILVISGSLPPGV--KLEKLTQLISAAQKQGIRCIVDSSG 169 E LE E+G ++ +L + +++ +LI+ + Sbjct: 153 TDRPAREACLEGARRMREAGGYVLFDVNLRSKMWGNTDEIPELIARSAA----------- 201 Query: 170 EALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQG 229 + K + EL L D R +++ ++SLG G Sbjct: 202 ----------LASICKVSADELCQLSGASHW--QDARYYLRDL----GCDTTIISLGADG 245 Query: 230 ALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLA-----ENASLEEMVRFGVAAGS 284 AL + +E P V T GAGD+ VG + L+ ++A L E + A G+ Sbjct: 246 ALLITAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEAISNANACGA 305 Query: 285 AATLNQGTRLCSHDDTQKIYAYLS 308 A +G + + ++ +LS Sbjct: 306 MAVTAKGA-MTALPFPDQLNTFLS 328 >5C40-A nrPDB Length = 330 Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats. Identities = 58/263 (22%), Positives = 102/263 (38%), Gaps = 13/263 (4%) Query: 38 GGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVAT-VEAKDWTRQNLHV 95 GG G N A LG + + G + G + L ++ + KD + Sbjct: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111 Query: 96 HVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISA 155 V G+ ++ GA L L I ++V + P LE LT Sbjct: 112 IVNNEGQNIIVIVAGANL-LLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTM---- 166 Query: 156 AQKQGIRCIVDSSGEALSAALAIGNI-ELVKPNQKELSALVNRELTQPDDVRKAAQEIVN 214 A++ G++ + + + + ++ N+ E L + D +AA ++ Sbjct: 167 ARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLK 226 Query: 215 SGKAKRVVVSLGPQGALGV--DSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAE--NA 270 G + V+++LG +G + + + VK+ T GAGDS VGA+ LA N Sbjct: 227 RG-CQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNL 285 Query: 271 SLEEMVRFGVAAGSAATLNQGTR 293 SLE+M+ + + GT+ Sbjct: 286 SLEDMLNRSNFIAAVSVQAAGTQ 308 >3GBU-A nrPDB Length = 313 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 58/292 (19%), Positives = 120/292 (41%), Gaps = 35/292 (11%) Query: 25 EGKLRCTAP-VFEPGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVAT 82 EG L+ PGG NVA ++ LG ++ I G GE+L+ L+ ENV Sbjct: 19 EGDLKDVRLFEKHPGGAPANVAVGVSRLGVKSSLISKVGNDPFGEYLIEELSKENVDTRG 78 Query: 83 VEAKDWTRQNLHVHVEASGEQYRFVMP------GAALNEDEFRQLEEQVLEIESGAILVI 136 + KD + V V+ G F++ LN+ + +EE + + G++++ Sbjct: 79 I-VKDEKKHTGIVFVQLKGASPSFLLYDDVAYFNMTLNDINWDIVEEAKI-VNFGSVILA 136 Query: 137 SGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVN 196 + +++ ++ I G +L A ++L + ++E+ ++ Sbjct: 137 R----------------NPSRETVMKVIKKIKGSSLIAFDVNLRLDLWRGQEEEMIKVLE 180 Query: 197 RELTQPDDVRKAAQEIVNSG-------KAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQ 249 + D V+ + +E++ + ++LGP+G + +E + V V Sbjct: 181 ESIKLADIVKASEEEVLYLENQGVEVKGSMLTAITLGPKGFRLIKNETVVDVPSYNVNPL 240 Query: 250 STVGAGDSMVGAMTLKL--AENASLEEMVRFGVAAGSAATLNQGTRLCSHDD 299 T GAGD+ + A+ + + + L ++ +F + +T +G D Sbjct: 241 DTTGAGDAFMAALLVGILKLKGLDLLKLGKFANLVAALSTQKRGAWSTPRKD 292 >3RY7-A nrPDB Length = 304 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 49/271 (18%), Positives = 104/271 (38%), Gaps = 11/271 (4%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATV-EAKDWTRQNLHV 95 GG G N A A A + T I G + ++ ++ + + + + + Sbjct: 40 GGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFI 99 Query: 96 HVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISA 155 V A G+ +V GA + + I + +V +P + Sbjct: 100 TVNAEGQNTIYVYGGANMTMTPED-VINAKDAIINADFVVAQLEVPIPAIISAF----EI 154 Query: 156 AQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNS 215 A+ G+ +++ + + I+++ PN+ E L ++T ++ A ++ Sbjct: 155 AKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSI 214 Query: 216 GKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENA-SLEE 274 G K V+++LG QG + V + T AGD+ +GA +L ++ +L + Sbjct: 215 G-IKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLAD 273 Query: 275 MVRFGVAAGSAATLNQGTR--LCSHDDTQKI 303 + FG A S G + + ++ ++ Sbjct: 274 AIDFGNKASSLTVQKHGAQASIPLLEEVNQV 304 >2NWH-A nrPDB Length = 317 Score = 143 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 61/265 (23%), Positives = 107/265 (40%), Gaps = 24/265 (9%) Query: 36 EPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLAD----ENVPVATVEAKDWT-- 89 E GGGG N AR ++ LG I P GG +V+ A E+ P ++ + + Sbjct: 37 EAGGGGFNAARNLSRLGFEVRIIAPRGGDVTGEVVAEAARQAGVEDTPFTFLDRRTPSYT 96 Query: 90 ----RQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVK 145 R V A + Y+ P + R + E ++ + L+ +LP Sbjct: 97 AILERDGNLVIALADMDLYKLFTP----RRLKVRAVREAII---ASDFLLCDANLPEDTL 149 Query: 146 LEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDV 205 LI+ A ++ + I S +A+ A+G+I+++ N+ E AL D Sbjct: 150 TAL--GLIARACEKPLAAIAISPAKAVKLKAALGDIDILFMNEAEARALTGETAENVRDW 207 Query: 206 RKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVK-SQSTVGAGDSMVGAMTL 264 ++ SG VV+ G + + + PP ++ + GAGD+M Sbjct: 208 PNILRKAGLSGG----VVTRGASEVVAFNGTEKAILHPPLIREVKDVTGAGDAMASGYLA 263 Query: 265 KLAENASLEEMVRFGVAAGSAATLN 289 +AE ++ E +R G AA + + Sbjct: 264 AIAEGKTIREALRQGAAAAAITVQS 288 >5ZWY-A nrPDB Length = 349 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 58/296 (19%), Positives = 103/296 (34%), Gaps = 19/296 (6%) Query: 13 LDSATITPQIYPEG-KLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLV 70 LD + G + + GG G N A A LG + G G + Sbjct: 46 LDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMVSMVGTDGDGSDYI 105 Query: 71 SLLADENVPVATVEAKDWTRQNLH-VHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIE 129 L V A + + L + V+ V+ A N L Q E Sbjct: 106 KELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPELLRAQTNNYE 165 Query: 130 SG-----AILVISGSLPPGVKLEKLTQLISAAQKQGIRCI-----VDSSGEALSAALAIG 179 L+ +P L+ + + A +G+ + E + Sbjct: 166 RILHTGLKYLICQNEIPLPTTLDTIKE----AHSRGVYTVFNSAPAPKPAEVEQIKPFLP 221 Query: 180 NIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSE-NC 238 + L PN+ E + + ++T + A + + G + VV++LG G + ++ Sbjct: 222 YVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLG-VRDVVITLGAAGFVLSENGAEP 280 Query: 239 IQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRL 294 + V VK+ T GAGD VG+M ++ +L E + + + +GT+L Sbjct: 281 VHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAISVTRKGTQL 336 >3KZH-A nrPDB Length = 328 Score = 137 bits (345), Expect = 5e-33, Method: Composition-based stats. Identities = 48/262 (18%), Positives = 98/262 (37%), Gaps = 9/262 (3%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVP-VATVEAKDWTRQNLHV 95 GG N+A +A +G + + G G+ +V ++ + + Sbjct: 42 GGVCRNIAENMARVGVNTNFMSILGNDEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLA 101 Query: 96 HVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISA 155 ++ +GE + ++ ++ + E+ V+ E + L+ Sbjct: 102 ILDENGEMVSAIADMKSIGAMNTDFIDSKREIFENAEYTVLD-----SDNPEIMEYLLKN 156 Query: 156 AQKQGIRCIVDSSGEALS-AALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVN 214 + + + S E S I + +KPN+ E L +T DD+ KA+ + Sbjct: 157 FKDKTNFILDPVSAEKASWVKHLIKDFHTIKPNRHEAEILAGFPITDTDDLIKASNYFLG 216 Query: 215 SGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEE 274 G K+V +SL G D +C ++ V ++ GAGDS V + +E+ Sbjct: 217 LG-IKKVFISLDADGIFYNDGVSCGKIKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIED 275 Query: 275 MVRFGVAAGSAATLNQGTRLCS 296 +V+F + + ++ T Sbjct: 276 IVKFAMTMSNITISHEETIHPD 297 >4X8F-A nrPDB Length = 309 Score = 134 bits (336), Expect = 6e-32, Method: Composition-based stats. Identities = 52/270 (19%), Positives = 103/270 (38%), Gaps = 10/270 (3%) Query: 37 PGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKDWTRQNLH- 94 PGG G N A A A + I G G ++ + + A V+ + + Sbjct: 40 PGGKGANQAVAAARMQADVGFIACVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAM 99 Query: 95 VHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLIS 154 + V SGE + A +E + I L++ P L+ + + Sbjct: 100 IQVSDSGENSICISAEANAKLTA-AAIEPDLAAIRDARYLLMQLETP----LDGILKAAQ 154 Query: 155 AAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVN 214 A+ I++ + + ++L+ PN+ E L + ++AA + Sbjct: 155 EAKTAKTNVILNPAPARELPDELLKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHC 214 Query: 215 SGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEE 274 G + V+++LG +G + ++ VK+ T AGD+ GA+ L + LE Sbjct: 215 KG-IEIVIITLGSKGVWLSQNGRGQRIPGFVVKATDTTAAGDTFNGALVTGLLQEMPLES 273 Query: 275 MVRFGVAAGSAATLNQGTR--LCSHDDTQK 302 ++F AA + + G + + + + + Sbjct: 274 AIKFAHAAAAISVTRFGAQTSIPTRAEVEA 303 >1RK2-A nrPDB Length = 309 Score = 132 bits (332), Expect = 2e-31, Method: Composition-based stats. Identities = 66/274 (24%), Positives = 112/274 (40%), Gaps = 9/274 (3%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEA-KDWTRQNLHV 95 GG G N A A G + I G GE + LA +N+ + V K + + Sbjct: 41 GGKGANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALI 100 Query: 96 HVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISA 155 V GE + GA +E Q I + + L++ P LE + Sbjct: 101 FVNGEGENVIGIHAGANAALSP-ALVEAQRERIANASALLMQLESP----LESVMAAAKI 155 Query: 156 AQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNS 215 A + ++ + + ++++ PN+ E L + +D KAAQ + Sbjct: 156 AHQNKTIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEK 215 Query: 216 GKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEM 275 G + V+++LG +G + +V V++ T+ AGD+ GA+ L E L E Sbjct: 216 G-IRTVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEA 274 Query: 276 VRFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR 309 +RF AA + A +G + S ++I A+L R Sbjct: 275 IRFAHAAAAIAVTRKGAQ-PSVPWREEIDAFLDR 307 >3PL2-A nrPDB Length = 319 Score = 117 bits (292), Expect = 7e-27, Method: Composition-based stats. Identities = 60/281 (21%), Positives = 110/281 (39%), Gaps = 24/281 (8%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKDWTRQNL--- 93 GG NV+ A A G ++ + G GE+L++ L V V + + Sbjct: 41 GGSAANVSVAAARHGHNSALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFC 100 Query: 94 HVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVI-----SGSLPPGVKLEK 148 + Y + P A + + + ++ IL S G E Sbjct: 101 EIFPPDDFPLYFYREPKAP--DLNIESADVSLDDVREADILWFTLTGFSEEPSRGTHREI 158 Query: 149 LTQLISAAQ---KQGIRCIVDSSGEAL--SAALAIGNIELVKPNQKELSALVNRELTQPD 203 LT + R + S E A A+ + + N++E V T+P+ Sbjct: 159 LTTRANRRHTIFDLDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGE--TEPE 216 Query: 204 DVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMT 263 +A + ++ G + +V GP+G + + + ++V P V + +GAGD+ GA+ Sbjct: 217 ---RAGRALLERG-VELAIVKQGPKGVMAMTKDETVEVPPFFVDVINGLGAGDAFGGALC 272 Query: 264 LKLAENASLEEMVRFGVAAGS--AATLNQGTRLCSHDDTQK 302 L LE+++RF AG+ A+ L T + + D+ + Sbjct: 273 HGLLSEWPLEKVLRFANTAGALVASRLECSTAMPTTDEVEA 313 >3HJ6-A nrPDB Length = 327 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 51/306 (16%), Positives = 105/306 (34%), Gaps = 26/306 (8%) Query: 16 ATITPQIYPEGKLRCTAPVFEP---GGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVS 71 + I E + GG N+A ++ LG I G G +L+ Sbjct: 29 EILVDMISTEEVNSLSQSREYTRHFGGSPANIAVNLSRLGKKVALISRLGADAFGNYLLD 88 Query: 72 LLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESG 131 +L E + ++ R + +++ A + E + E I+ Sbjct: 89 VLKGEQIITDGIQQDKERRTTIVYVSKSTRTPDWLPYREADMYLQEDDIIFE---LIKRS 145 Query: 132 AILVISGSLPPGVKL-EKLTQLISAAQKQGIRC--------IVDSSGEALSAALA--IGN 180 + +S + + + + A++QG ++ G+ + + I Sbjct: 146 KVFHLSTFILSRKPARDTAIKAFNYAREQGKIVCFDPCYRKVLWPEGDDGAGVVEEIISR 205 Query: 181 IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ 240 + VKP+ + L PD + + G K V+++LG +G + D E I+ Sbjct: 206 ADFVKPSLDDARHLFG-----PDSPENYVKRYLELG-VKAVILTLGEEGVIASDGEEIIR 259 Query: 241 VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGT--RLCSHD 298 + + GAGD+ L + +++ ++ G + G + S + Sbjct: 260 IPAFSEDAVDVTGAGDAFWSGFICGLLDGYTVKRSIKLGNGVAAFKIRGVGALSPVPSKE 319 Query: 299 DTQKIY 304 D K Y Sbjct: 320 DIIKEY 325 >3H49-A nrPDB Length = 325 Score = 115 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 109/298 (36%), Gaps = 23/298 (7%) Query: 4 IYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGG 63 I + L P + YP GG IN A I+ LG + G Sbjct: 15 IVDIPLQP-VSKNIFDVDSYP-----LERIAMTTGGDAINEATIISRLGHRTALMSRIGK 68 Query: 64 AT-GEHLVSLLADENVPVATVEAKDWTRQNLHV-HVEASGEQYRFVMPGAALNEDEFRQL 121 G+ ++ EN+ + +++ +++V V GE+ +L + + Sbjct: 69 DAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGSLWKLNIDDV 128 Query: 122 EEQVLEIESGAIL-VISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAAL---- 176 +L + S P + + LT++ + A+ + + D L+ L Sbjct: 129 --DFARFSQAKLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKPRLNETLDDIC 186 Query: 177 -AIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDS 235 A+ ++ + PN E L + + + + A + G K VV+ G G Sbjct: 187 EALSYVDYLFPNFAEAKLLTGK-----ETLDEIADCFLACG-VKTVVIKTGKDGCFIKRG 240 Query: 236 ENCIQVVPPP-VKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGT 292 + ++V + + T+GAGD+ L E +L E RF A + + L+ G Sbjct: 241 DMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNLRECARFANATAAISVLSVGA 298 >1V1S-A nrPDB Length = 309 Score = 101 bits (250), Expect = 6e-22, Method: Composition-based stats. Identities = 59/284 (20%), Positives = 98/284 (34%), Gaps = 34/284 (11%) Query: 38 GGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVATVEAKDWTRQNLHVH 96 GG +NVA A+A LG + G G + L E V + Sbjct: 33 GGAEVNVAVALARLGVKVGFVGRVGEDELGAMVEERLRAEGVDLTHFRRAPGFTGLYLRE 92 Query: 97 VEASGEQYRFVM----PGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQL 152 G+ F G+AL F +E L +SG P + L Sbjct: 93 YLPLGQGRVFYYRKGSAGSALAPGAFDP-----DYLEGVRFLHLSGITPALSPEARAFSL 147 Query: 153 --ISAAQKQGIRCIVDS-------SGEALSAAL--AIGNIELVKPNQKELSALVNRELTQ 201 + A+++G+R +D S E L A+ ++L+ +++E L R Sbjct: 148 WAMEEAKRRGVRVSLDVNYRQTLWSPEEARGFLERALPGVDLLFLSEEEAELLFGR---- 203 Query: 202 PDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGA 261 V +A + + A VV+ G +GA ++ V++ VGAGD+ Sbjct: 204 ---VEEALRAL----SAPEVVLKRGAKGAWAFVDGRRVEGSAFAVEAVDPVGAGDAFAAG 256 Query: 262 MTLKLAENASLEEMVRFGV--AAGSAATLNQGTRLCSHDDTQKI 303 +EE +R A AA+ +D + + Sbjct: 257 YLAGAVWGLPVEERLRLANLLGASVAASRGDHEGAPYREDLEVL 300 >3IQ0-A nrPDB Length = 330 Score = 100 bits (249), Expect = 7e-22, Method: Composition-based stats. Identities = 54/287 (18%), Positives = 107/287 (37%), Gaps = 24/287 (8%) Query: 37 PGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKD-WTRQNLH 94 P G + LG I G G+ + LA + V + + + Sbjct: 36 PSGAPAIFIDQVTRLGVPCGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAF 95 Query: 95 VHVEASGEQ-YRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLI 153 V SG++ + F + AA + + ++E +L+ + ++ SL ++ + + + Sbjct: 96 VTYHNSGDRDFIFNIKNAACGKLSAQHVDENILK-DCTHFHIMGSSLFSFHMVDAVKKAV 154 Query: 154 SAAQKQG---------IRCIVDSSG--EALSAALAIGNIELVKPNQKELSALVNRELTQP 202 + + G + ++D +AL L + +I + P++ E+ L + P Sbjct: 155 TIVKANGGVISFDPNIRKEMLDIPEMRDALHFVLELTDIYM--PSEGEVLLLS--PHSTP 210 Query: 203 DDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAM 262 + +A + G K V+V G QGA + V PV+ GAGD GA Sbjct: 211 E---RAIAGFLEEG-VKEVIVKRGNQGASYYSANEQFHVESYPVEEVDPTGAGDCFGGAW 266 Query: 263 TLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR 309 +++ A G+ A +G + +I ++ R Sbjct: 267 IACRQLGFDAHRALQYANACGALAVTRRGP-MEGTSRLMEIETFIQR 312 >2C4E-A nrPDB Length = 302 Score = 98.4 bits (243), Expect = 3e-21, Method: Composition-based stats. Identities = 51/308 (16%), Positives = 100/308 (32%), Gaps = 35/308 (11%) Query: 12 SLDSATITPQI-YPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLV 70 +LD + P ++ + GG N A I LG ++ + G Sbjct: 15 ALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLSCVGYDFKNSGY 74 Query: 71 SL-LADENVPVA-TVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEI 128 L + ++ ++ +++ + + Q F + GAA + +E Sbjct: 75 ERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAA------KHYKELNPPN 128 Query: 129 ESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEAL------SAALAIGNIE 182 + I+ I+ P L A + G + G+ L I + Sbjct: 129 FNTEIVHIATGDPEFN-------LKCAKKAYGNNLVSFDPGQDLPQYSKEMLLEIIEHTN 181 Query: 183 LVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVV 242 + N+ E N + DD + ++V+ G +G++ + I++ Sbjct: 182 FLFMNKHEFERASNLLNFEIDDY---------LERVDALIVTKGSKGSVIYTKDKKIEIP 232 Query: 243 -PPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQG--TRLCSHDD 299 K GAGDS + LE+ G A S +G T L + D Sbjct: 233 CIKAGKVIDPTGAGDSYRAGFLSAYVKGYDLEKCGLIGAATASFVVEAKGCQTNLPTWDK 292 Query: 300 -TQKIYAY 306 +++ + Sbjct: 293 VVERLEKH 300 >3I3Y-A nrPDB Length = 299 Score = 98.0 bits (242), Expect = 5e-21, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 89/266 (33%), Gaps = 26/266 (9%) Query: 1 MVRIYTLTLAPSLDSATITPQIYPEG-KLRCTAPVFEPGGGGINVARAIAHLGGSATAIF 59 M +T ++D P I +G + + GG G N A ++ G I Sbjct: 1 MSLRVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIA 60 Query: 60 PAGGA-TGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEF 118 G G + + +E + + + + A G+ + AA + Sbjct: 61 ATGNDSNGAWIRQQIKNEPLMLLPDGHFNQHSDTSIILNSADGDN-AIITTTAAADTFSL 119 Query: 119 RQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAI 178 ++ + + +G IL+ G+ L+K L A+ +G+ + + S Sbjct: 120 DEMIPHMADAVAGDILLQQGN----FSLDKTRALFQYARSRGMTTVFNPSPVNPDFCHLW 175 Query: 179 GNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENC 238 I++ N+ E ++ K +V++ G GA V Sbjct: 176 PLIDIAVVNESEAE-------------------LLQPYGVKTLVITQGAAGAWLVQEGQR 216 Query: 239 IQVVPPPVKSQSTVGAGDSMVGAMTL 264 P ++ T GAGD+ + M Sbjct: 217 QFCPAVPAEALDTTGAGDTFLAVMLA 242 >2QCV-A nrPDB Length = 332 Score = 96.8 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 48/286 (16%), Positives = 96/286 (33%), Gaps = 19/286 (6%) Query: 34 VFEPGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKDW-TRQ 91 GG N+ + LG A I G + S + V + + + Sbjct: 40 SKYVGGSPANIVIGSSKLGLKAGFIGKIADDQHGRFIESYMRGVGVDTSNLVVDQEGHKT 99 Query: 92 NLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGS-LPPGVKLEKLT 150 L S E+ +M + + E I +L++SG+ L E + Sbjct: 100 GLAFTEIKSPEECSILMYRQDVADLYLSPEEVNEAYIRRSKLLLVSGTALSKSPSREAVL 159 Query: 151 QLISAAQKQGIRCIVDS-----SGEALSAALAIGNI-----ELVKPNQKELSALVNRELT 200 + I A++ ++ + + S E ++ ++V ++E L NR Sbjct: 160 KAIRLAKRNDVKVVFELDYRPYSWETPEETAVYYSLVAEQSDIVIGTREEFDVLENRTEK 219 Query: 201 QPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENC-IQVVPPPVKSQSTVGAGDSMV 259 +D + + +V+ G +G+ + K T GAGDS Sbjct: 220 GDND---ETIRYLFKHSPELIVIKHGVEGSFAYTKAGEAYRGYAYKTKVLKTFGAGDSYA 276 Query: 260 GAMTLKLAENASLEEMVRFGVAAGSAATLNQGT--RLCSHDDTQKI 303 A L +E +++G A+ S + + S ++ + + Sbjct: 277 SAFLYALISGKGIETALKYGSASASIVVSKHSSSDAMPSVEEIEAL 322 >6CW5-A nrPDB Length = 332 Score = 94.9 bits (234), Expect = 4e-20, Method: Composition-based stats. Identities = 58/319 (18%), Positives = 103/319 (32%), Gaps = 32/319 (10%) Query: 13 LDSATITPQIYPEG-KLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVS 71 +D P I G + T GG G N A A+A GG G G + Sbjct: 23 IDEFFHLPHIVRPGETISSTGLTKRAGGKGANQAFAVARAGGQVELDGAIGDD-GIWVKE 81 Query: 72 LLADENVPVATVE-AKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIES 130 +L V ++ KD + A GE + GA + + Sbjct: 82 MLESAGVGTDKLKIVKDEVTGRAVIQSAADGENSIVLHAGANYYLPS----PTPTTSLAT 137 Query: 131 GAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAA----LAIGNIELVKP 186 L++ +P L L +A Q V + L+ A ++ + Sbjct: 138 YTHLLVQNEVPLS---STLAYLTAAGQSSPPLTSVFNPSPMLTPAQLREFPWKHLSWLIV 194 Query: 187 NQKELSALV---NRELTQPDDVRKAAQEIVNSGKAKR-----------VVVSLGPQGALG 232 N+ EL L+ + Q ++G + ++ +LG +G L Sbjct: 195 NEGELGDLLLAFGSSANPGEAKEDELQAKASAGILELHENDYFSKNVGIICTLGAKGILC 254 Query: 233 VD-SENCIQVVPPPVK--SQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLN 289 + + + ++ + T GAGD G L SL++ ++ + A N Sbjct: 255 YEPGKEVGYLPAAKLQNPVKDTTGAGDCFAGYFVAGLMSGKSLQDALKTCLVACGICVEN 314 Query: 290 QGTRLCSHDDTQKIYAYLS 308 +G + S + L+ Sbjct: 315 EGA-MESVPTLNAVKERLA 332 >4E84-A nrPDB Length = 352 Score = 89.1 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 54/264 (20%), Positives = 95/264 (35%), Gaps = 9/264 (3%) Query: 39 GGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVATVEAKDWTRQNLHVHV 97 GG NVAR LGG A + G GE +V LL V +E + + V Sbjct: 94 GGAANVARNAVTLGGQAGLLCVVGCDEPGERIVELLGSSGV-TPHLERDPALPTTIKLRV 152 Query: 98 EASGEQY-RFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAA 156 A +Q R +E L + + ++++S G+ +T +I A Sbjct: 153 LARQQQLLRVDFEAMPTHEVLLAGLARFDVLLPQHDVVLMSDYAKGGLT--HVTTMIEKA 210 Query: 157 QKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSG 216 + G +VD G+ + L+ PN+ EL +V + DD+R + Sbjct: 211 RAAGKAVLVDPKGDDWAR---YRGASLITPNRAELREVVGQ-WKSEDDLRARVANLRAEL 266 Query: 217 KAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV 276 ++++ +G + + + GAGD+++ + L L + V Sbjct: 267 DIDALLLTRSEEGMTLFSAGGELHAPALAREVFDVSGAGDTVIATVATMLGAGVPLVDAV 326 Query: 277 RFGVAAGSAATLNQGTRLCSHDDT 300 A GT +D+ Sbjct: 327 VLANRAAGIVVGKLGTATVDYDEL 350 >3LJS-A nrPDB Length = 338 Score = 89.1 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 63/295 (21%), Positives = 107/295 (36%), Gaps = 38/295 (12%) Query: 37 PGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKDWTRQNL-H 94 GG NVA A+A LGG+ + G G+ L A+ V + + L Sbjct: 35 AGGAPANVAVAVARLGGAVQFVGMLGSDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAF 94 Query: 95 VHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILV---ISGSLPPGVKLEKLTQ 151 V ++A GE+ F + FR E + L+ S S+ E + Sbjct: 95 VALDAHGERS-FSFYRPPAADLLFRV--EHFQDASFSDALIFHACSNSMTDADIAEVTFE 151 Query: 152 LISAAQKQGIRC--------IVDSSGEALSAAL--AIGNIELVKPNQKELSALVNRELTQ 201 + AQ G ++ +GE ++ L + ++VK + +EL L N Sbjct: 152 GMRRAQAAGAIVSFDLNFRPMLWPNGENPASRLWKGLSLADVVKLSSEELDYLANTLAAD 211 Query: 202 PDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGA 261 + V + + G+A+ ++V+ +V V+ Q + AGD+ VG Sbjct: 212 ANAVIQQ----LWQGRAQLLLVTDAAGPVHWYTRTAGGEVPTFRVQVQDSNAAGDAFVGG 267 Query: 262 MTLKLAEN--------------ASLEEMVRFGVAAGSAATLNQG--TRLCSHDDT 300 M A+ S+ +RF A G+ A QG T + + Sbjct: 268 MLYTFAQQFDDAAALIDFCHDPESIVSTLRFAAAVGALAVTRQGAFTAMPMLSEV 322 >3NCA-A nrPDB Length = 313 Score = 88.4 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 47/272 (17%), Positives = 97/272 (35%), Gaps = 30/272 (11%) Query: 23 YPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA 81 + ++RC + ++ GG N ++ LG + G + LV+ V V+ Sbjct: 40 KEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVS 99 Query: 82 TV--EAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGS 139 V ++K T + + ++G + + + + + + +++ + I G Sbjct: 100 QVAWQSKGDTPSSCCIINNSNGNRTIVLH---DTSLPDVSATDFEKVDLTQFKWIHIEGR 156 Query: 140 LPPG---VKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVN 196 + +Q IR V+ G ++V ++ L Sbjct: 157 NASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHL-- 214 Query: 197 RELTQPDDVRKAAQEIVNSGKAKRVVV---------SLGPQGALGVDSENCIQVVPPPVK 247 +A + + + V+V +LGP G L PP V Sbjct: 215 ----GFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA----FPPPRV- 265 Query: 248 SQSTVGAGDSMVGAMTLKLAENASLEEMVRFG 279 T+GAGD+ ++ L++ S++E +RFG Sbjct: 266 -VDTLGAGDTFNASVIFSLSQGRSVQEALRFG 296 >2QHP-A nrPDB Length = 296 Score = 88.4 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 44/280 (15%), Positives = 90/280 (32%), Gaps = 26/280 (9%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKDWTRQNLHVH 96 GG N A ++ G + + G G+ ++ + ++ + +E D+ + V Sbjct: 24 GGAPANFAYHVSQFGFDSRVVSAVGNDELGDEIMEVFKEKQLKNQ-IERVDYPTGTVQVT 82 Query: 97 VEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAA 156 ++ G + G A + F +++ V GSL ++ A Sbjct: 83 LDDEGVPCYEIKEGVAWDNIPFTDELKRLALNTRA---VCFGSLAQR------NEVSRAT 133 Query: 157 QKQGIRCIVDSSGEALS--------------AALAIGNIELVKPNQKELSALVNRELTQP 202 + + + D G+ + ++K N +EL + Sbjct: 134 INRFLDTMPDIDGQLKIFDINLRQDFYTKEVLRESFKRCNILKINDEELVTISRMFGYPG 193 Query: 203 DDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAM 262 D++ ++ K ++++ G G+ P V TVGAGDS A Sbjct: 194 IDLQDKCWILLAKYNLKMLILTCGINGSYVFTPGVVSFQETPKVPVADTVGAGDSFTAAF 253 Query: 263 TLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQK 302 + S+ E + V + G + K Sbjct: 254 CASILNGKSVPEAHKLAVEVSAYVCTQSGA-MPELPVILK 292 >5KB6-A nrPDB Length = 363 Score = 84.5 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 51/294 (17%), Positives = 97/294 (32%), Gaps = 19/294 (6%) Query: 25 EGKLRCTAPVFEPGGGGINVARAIAHLGGS----ATAIFPAG-GATGEHLVSLLADENVP 79 + ++ + GG N + L AT G GE L AD +V Sbjct: 68 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVD 127 Query: 80 VATVEAKDWTRQNLHVHVEASGEQYRFVMPGAAL-NEDEFRQLEEQVLEIESGAILVISG 138 E + + + A +++ LE + +E + I+G Sbjct: 128 AHYYEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAG 187 Query: 139 SLPPGVKLEKLTQLISAAQKQGIRCIVDSSG---EALSAAL--AIGNIELVKPNQKELSA 193 L AA+ + + S+ + AL + ++++ N+ E + Sbjct: 188 FFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGNETEAAT 247 Query: 194 LVNRELTQPDDVRKAAQEI-----VNSGKAKRVVVSLGPQGALGVDSENCIQVVP---PP 245 + + D+++ A++ VNS + + V+ + G + + Sbjct: 248 FAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQ 307 Query: 246 VKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDD 299 + T GAGD+ VG +L + L E +R G A S G D Sbjct: 308 EEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTGCTFPEKPD 361 >2I6B-A nrPDB Length = 345 Score = 83.7 bits (205), Expect = 9e-17, Method: Composition-based stats. Identities = 48/295 (16%), Positives = 98/295 (33%), Gaps = 21/295 (7%) Query: 25 EGKLRCTAPVFEPGGGGINVARAIAHLGGS-----ATAIFPAG-GATGEHLVSLLADENV 78 + ++ + GG N + +A AT G GE L A+ +V Sbjct: 50 DELVKKFKVEYHAGGSTQN-SIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHV 108 Query: 79 PVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAAL-NEDEFRQLEEQVLEIESGAILVIS 137 E + + + A +++ LE+ + +E + I+ Sbjct: 109 DAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIA 168 Query: 138 GSLPPGVKLEKLTQLISAAQKQGIRCIVDSSG---EALSAAL--AIGNIELVKPNQKELS 192 G L A++ I + S+ + +L + ++++ N+ E + Sbjct: 169 GFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAA 228 Query: 193 ALVNRELTQPDDVRKAAQEI-----VNSGKAKRVVVSLGPQGALGVDSENCIQVVP---P 244 + + D+++ A++ +NS + + V+ + G + Sbjct: 229 TFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQD 288 Query: 245 PVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDD 299 + T GAGD+ VG +L + L E +R G A S G D Sbjct: 289 QKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD 343 >4DU5-A nrPDB Length = 336 Score = 83.4 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 62/328 (18%), Positives = 102/328 (31%), Gaps = 37/328 (11%) Query: 4 IYTLTLAPSLDSATITPQIYPEGKLR------CTAPVFEPGGGGINVARAIAHLGGSATA 57 +Y ++ +LD T + R A G NVA +A LG Sbjct: 18 LYFQSMTSALDVITFGEAMMLLVADRPGPLEHAEAFHKRTAGAETNVAIGLARLGLKVGW 77 Query: 58 IFPAGGA-TGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNED 116 G G +L++ +A E + + V + + G+ P + Sbjct: 78 ASRLGTDSMGRYLLAAMAAEGIDCSHVVCDATQKTGF----QFKGKVTDGSDPPVEYHRK 133 Query: 117 EFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQ---------------GI 161 V +I+ +L GV + AA+K + Sbjct: 134 GSAASHMGVADIDEAWLLSARHLHATGVFPAISATTLPAARKTMDLMRAAGRSVSFDPNL 193 Query: 162 RCIVDSSGEALSAAL--AIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAK 219 R + ++ E + A+ + V P +E L + AK Sbjct: 194 RPTLWATPELMRDAINDLATRADWVLPGMEEGRFLTGETTPE------GVARFYRQLGAK 247 Query: 220 RVVVSLGPQGALGVDSENCIQVVPPPV-KSQSTVGAGDSMVGAMTLKLAENASLEEMVRF 278 VVV LG +GA +V PV + TVGAGD + L + + E V+ Sbjct: 248 LVVVKLGAEGAYFDGEAGSGRVAGFPVAEVVDTVGAGDGFAVGVISALLDGLGVPEAVKR 307 Query: 279 GVAAGSAATLNQG--TRLCSHDDTQKIY 304 G G+ A G L + + Sbjct: 308 GAWIGARAVQVLGDSEGLPTRAELNAAK 335 >1WYE-A nrPDB Length = 311 Score = 83.0 bits (203), Expect = 2e-16, Method: Composition-based stats. Identities = 48/310 (15%), Positives = 99/310 (31%), Gaps = 21/310 (6%) Query: 14 DSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSL 72 + + P + G N A G I G G + + Sbjct: 9 EILIEFNALSPGPLRHVSYFEKHVAGSEANYCVAFIKQGNECGIIAKVGDDEFGYNAIEW 68 Query: 73 LADENVPVATVEAKDWTRQNLHVH-----VEASGEQYRFVMPGAALNEDEFRQLEEQVLE 127 L + V V+ ++ + V E + A EE V Sbjct: 69 LRGQGVDVSHMKIDPSAPTGIFFIQRHYPVPLKSESIYYRKGSAGSKLSPEDVDEEYVKS 128 Query: 128 ---IESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN---I 181 + S I + S + + + IR + S+ EA L + + + Sbjct: 129 ADLVHSSGITLAISSTAKEAVYKAFEIASNRSFDTNIRLKLWSAEEAKREILKLLSKFHL 188 Query: 182 ELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQV 241 + + + + ++ D KAA+ + A+ +V+ LGP+GA+ Sbjct: 189 KFLITDTDDSKIILGES-----DPDKAAKAFSD--YAEIIVMKLGPKGAIVYYDGKKYYS 241 Query: 242 VPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTR--LCSHDD 299 V + GAGD++ G + +E+ + + + A + + +G + L + D Sbjct: 242 SGYQVPVEDVTGAGDALGGTFLSLYYKGFEMEKALDYAIVASTLNVMIRGDQENLPTTKD 301 Query: 300 TQKIYAYLSR 309 + + + Sbjct: 302 IETFLREMKK 311 >4WJM-A nrPDB Length = 312 Score = 82.6 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 59/303 (19%), Positives = 98/303 (32%), Gaps = 35/303 (11%) Query: 18 ITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAI-FPAGGATGEHLVSLLADE 76 + + E TA GG N A A+ LG + G+ L LA Sbjct: 15 LIDMLPRETTGGETAFQPFAGGSVFNTAIALGRLGVPTGFFSGISSDFFGDVLRDTLARS 74 Query: 77 NVPVATVEAKDWTRQNLHVHVEASGEQYRF---VMPGAALNEDEFRQLEEQVLEIESGAI 133 NV + + V + +Y F G L+ ++ ++E + + G I Sbjct: 75 NVDYSFAAISNRPTTLAFVRLVDGQARYAFYDENTAGRMLSRNDMPYVDETISAMLFGCI 134 Query: 134 LVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEAL--------SAALAIGNIELVK 185 +I S P G E L L A + + + + I ++VK Sbjct: 135 SLI--SEPCGSVYETL--LAREAPNRVMFLDPNIRANLITVRKTHLTRMKRMIALADIVK 190 Query: 186 PNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPP 245 + ++L + + A E + G K VV++ G GA+ + + V Sbjct: 191 LSDEDL-----DWFGEKGSHDEIAAEWLKLGP-KLVVITKGAHGAVAYTNHATVPVPGVK 244 Query: 246 VKSQSTVGAGDSMVGAMTLKL-------------AENASLEEMVRFGVAAGSAATLNQGT 292 V TVGAGD++ + L + V GV A + G Sbjct: 245 VDVVDTVGAGDTVNAGILASLHSQGLLTKDALANLSEDQIHSAVALGVRAAAVTVSRAGA 304 Query: 293 RLC 295 Sbjct: 305 NPP 307 >3KD6-A nrPDB Length = 313 Score = 81.0 bits (198), Expect = 7e-16, Method: Composition-based stats. Identities = 47/263 (17%), Positives = 87/263 (33%), Gaps = 18/263 (6%) Query: 38 GGGGINVARAIAHL-GGSATAIFPAGGATGEHLVSLLADENVPVATVEA--KDWT-RQNL 93 GG +A + ++ + G G+ LL +N+ ++ T R Sbjct: 28 GGSSTYIALSASYFTDEPIRMVGVVGSDFGKEHFDLLHAKNIDTRGIQVIEDGKTFRWAG 87 Query: 94 HVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLI 153 H + + + F + + V + + V G++ P ++L+ L Q+ Sbjct: 88 RYHYDMNTRDTL------DTQLNVFAEFDPHVPQYYRDSKFVCLGNIDPELQLKVLDQID 141 Query: 154 SAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIV 213 G+ + +++ N E L ++ K A+ I Sbjct: 142 DPKLVVCDTMNFWIEGKPEELKKVLARVDVFIVNDSEARLLSGDP-----NLVKTARIIR 196 Query: 214 NSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQ-STVGAGDSMVGAMTLKLAENASL 272 G K +++ G GAL P++S GAGD+ G LA + Sbjct: 197 EMGP-KTLIIKKGEHGALLFTDNGIFAAPAFPLESIYDPTGAGDTFAGGFIGHLARCGNT 255 Query: 273 EEM-VRFGVAAGSAATLNQGTRL 294 E +R V GSA + Sbjct: 256 SEAEMRKAVLYGSAMASFCVEQF 278 >2HW1-A nrPDB Length = 298 Score = 80.7 bits (197), Expect = 8e-16, Method: Composition-based stats. Identities = 45/272 (16%), Positives = 92/272 (33%), Gaps = 30/272 (11%) Query: 23 YPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA 81 + ++RC + ++ GG N ++ LG + G + ++ L +V + Sbjct: 25 KEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFVLDDLRRYSVDLR 84 Query: 82 TV--EAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGS 139 + + EASG + + + + + +++ + I G Sbjct: 85 YTVFQTTGSVPIATVIINEASGSRTILYY---DRSLPDVSATDFEKVDLTQFKWIHIEGR 141 Query: 140 LPPG---VKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVN 196 + +Q IR V+ G ++V ++ L Sbjct: 142 NASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHL-- 199 Query: 197 RELTQPDDVRKAAQEIVNSGKAKRVVV---------SLGPQGALGVDSENCIQVVPPPVK 247 +A + + + V+V +LGP G L PP V Sbjct: 200 ----GFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA----FPPPRV- 250 Query: 248 SQSTVGAGDSMVGAMTLKLAENASLEEMVRFG 279 T+GAGD+ ++ L++ S++E +RFG Sbjct: 251 -VDTLGAGDTFNASVIFSLSQGRSVQEALRFG 281 >4N08-A nrPDB Length = 348 Score = 79.5 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 52/295 (17%), Positives = 88/295 (29%), Gaps = 21/295 (7%) Query: 25 EGKLRCTAPVFEPGGGGINVARAI-----AHLGGSATAIFPAGGA-TGEHLVSLLADENV 78 + + + PGG G+NVAR A+ G T + G+ L E + Sbjct: 52 DDIEKMPNVRYVPGGSGLNVARVAQWMQQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGI 111 Query: 79 PVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISG 138 +A V + + A E + V ++ I SG Sbjct: 112 VMAVEHTTKAGSGACAVCITGKERTLVADLGAANHLSSEHMRSPAVVRAMDESRIFYFSG 171 Query: 139 SLPPGVKLEKLTQLISAAQK-QGIRCIVDSSGEALSAALA-----IGNIELVKPNQKELS 192 V + + Q A++ G+ I S+ + A + +++ N+ E Sbjct: 172 -FTLTVDVNHVLQACRKAREVDGLFMINLSAPFIMQFFSAQLGEVLPYTDIIVANRHEAK 230 Query: 193 ALVNRELTQPD----DVRKAAQEIVNSGKAKRVVV-SLGPQGALGVDSENCIQVVPPPVK 247 N D R+A E+ +G RVVV + + + + V P + Sbjct: 231 EFANMMKWDTDCVEEIARRAVSEVPYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLD 290 Query: 248 ---SQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDD 299 GAGD+ +G A L G G Sbjct: 291 QDKVIDMNGAGDAFMGGFLSAYAVGKDLRRCCETGHYTAQEVIQRDGCSFPEKPS 345 >3UBO-A nrPDB Length = 354 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 56/282 (19%), Positives = 90/282 (31%), Gaps = 22/282 (7%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKDWT-RQNLHV 95 GG N A +A LGG A GE + + V T + Sbjct: 60 GGSAGNTAAGVASLGGRAAYFGKVADDQLGEIFTHDIRAQGVHFQTKPLDGHPPTARSMI 119 Query: 96 HVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSL-PPGVKLEKLTQLIS 154 V GE+ GA + ++ + + G L P + + + Sbjct: 120 FVTEDGERSMNTYLGACVELGPEDVEDDV---VAQSKVTYFEGYLWDPPRAKDAIREAAR 176 Query: 155 AAQKQGIRCIVDSSG-----EALSAALAI---GNIELVKPNQKELSALVNRELTQPDDVR 206 A G + S S L + G +++V N++E AL + +D Sbjct: 177 IAHAHGRETAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALALY-----ETEDFD 231 Query: 207 KAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPV-KSQSTVGAGDSMVGAMTLK 265 +A + + K V+L +G++ V ++V + + T GAGD Sbjct: 232 RALELLAR--DCKLAAVTLSEEGSVVVRGAERVRVGASVLEQVVDTTGAGDLYAAGFLFG 289 Query: 266 LAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKIYAYL 307 SLEE + G A G R T A L Sbjct: 290 YTSGRSLEECSKLGNLAAGIVIGQIGPRPLVSLATAARQAAL 331 >2RBC-A nrPDB Length = 343 Score = 77.6 bits (189), Expect = 6e-15, Method: Composition-based stats. Identities = 49/293 (16%), Positives = 102/293 (34%), Gaps = 21/293 (7%) Query: 25 EGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATV 83 EGK+ + G + A A+ +GG A+ G TG ++ L++ + + + Sbjct: 53 EGKVLPYEVLQIAEGMASSAAYAVHRMGGRASLWGAVGDDETGTRILRDLSESGIDTSGM 112 Query: 84 EAKDWTRQNLH-VHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPP 142 R L + ++ GE+ +L E+ I + L Sbjct: 113 TVAPGARSALSTIIIDNRGERLIVPFYD--------HRLHEKKRACTPEDIALFDAVLVD 164 Query: 143 GVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIEL-VKPNQKELSALVNRELTQ 201 E +++ A+ G I+D + + + ++ + L Sbjct: 165 VRWPELALDVLTVARALGKPAILDGDVAPVETLEGLAPAATHIVFSEPAATRLTGL---- 220 Query: 202 PDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENC-IQVVPP-PVKSQSTVGAGDSMV 259 + V+ + + V+ GP G ++++ + V++ T+ AGD Sbjct: 221 -ETVKDMLPVLHARYPQTFIAVTAGPAGCWWTEADDPTVHFQTTMQVEAVDTLAAGDIFH 279 Query: 260 GAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRL--CSHDDT-QKIYAYLSR 309 G L +AE VR A + G R+ + ++T + + +L R Sbjct: 280 GTFALAMAEGMQSRAAVRLSSVAAALKCTVFGGRIGAPTREETEEAMRQWLER 332 >4LC4-A nrPDB Length = 352 Score = 77.2 bits (188), Expect = 9e-15, Method: Composition-based stats. Identities = 55/283 (19%), Positives = 92/283 (32%), Gaps = 33/283 (11%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNL---- 93 GG N A +A+LGG A + + ++ V + + Sbjct: 80 GGSAGNTAAGVANLGGKAAYFGNVAADQLGDIFT----HDIRAQGVHYQTKPKGAFPPTA 135 Query: 94 --HVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSL-PPGVKLEKLT 150 + V GE+ GA + + V + + G L P E + Sbjct: 136 RSMIFVTEDGERSMNTYLGACVELGPEDVEADVVAD---AKVTYFEGYLWDPPRAKEAIL 192 Query: 151 QLISAAQKQG---------IRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQ 201 A + G C+ GE L + G +++V N++E +L Q Sbjct: 193 DCARIAHQHGREMSMTLSDSFCVDRYRGEFLDL-MRSGKVDIVFANRQEALSLY-----Q 246 Query: 202 PDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVK-SQSTVGAGDSMVG 260 DD +A I + K V++ GA+ + V ++ T GAGD Sbjct: 247 TDDFEEALNRI--AADCKIAAVTMSENGAVILKGRERYYVNAIRIREVVDTTGAGDLFAS 304 Query: 261 AMTLKLAENASLEEMVRFGVAAGSAATLNQGTR-LCSHDDTQK 302 + SLE+ + G A G R + S + K Sbjct: 305 GFLYGYTQGRSLEDCGKLGCLAAGIVIQQIGPRPMTSLSEAAK 347 >6C9R-A nrPDB Length = 337 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 57/287 (19%), Positives = 95/287 (33%), Gaps = 24/287 (8%) Query: 18 ITPQIYPEGKLRC------TAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVS 71 + Q+ PE + V GG N+A AI LGG + AG ++ Sbjct: 34 FSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADY-RD 92 Query: 72 LLADENVPVATVEA-KDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIES 130 L V V + + Q PGA ++E +L + V I Sbjct: 93 WLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGA-MSEARNIKLADVVSAIGK 151 Query: 131 GAILVISGSLPPGV--KLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQ 188 +++I + P + E+ +L A + + SGE + + + N Sbjct: 152 PELVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSGEEIRRLVNGAA--YLFTND 209 Query: 189 KELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENC-IQV-VPPPV 246 E L+++ DV + V +LGP+G V+ + I V V P Sbjct: 210 YEWDLLLSKTGWSEADV---------MAQIDLRVTTLGPKGVDLVEPDGTTIHVGVVPET 260 Query: 247 KSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTR 293 G GD+ + LE + G + GT+ Sbjct: 261 SQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQ 307 >3B1N-A nrPDB Length = 326 Score = 74.5 bits (181), Expect = 5e-14, Method: Composition-based stats. Identities = 45/304 (14%), Positives = 89/304 (29%), Gaps = 36/304 (11%) Query: 18 ITPQIYPEGKLRCTAPVFEP------GGGGINVARAIAHLGGSATAIFPAGGATGEHLVS 71 I P+ P GG N+A A+ LGG A + G + + Sbjct: 21 FREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGDARMMGTLGAVDAQPYLD 80 Query: 72 LLADENVPVATVEAKDWT-RQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIES 130 + + V T + + Q PGA + E + +++ Sbjct: 81 RMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFHPGAMMQSHVNHAGEAKDIKLAI 140 Query: 131 GAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALA------IGNIELV 184 P G + + Q + G+ I D G+ L I + Sbjct: 141 VG--------PDGFQ--GMVQHTEELAQAGVPFIFD-PGQGLPLFDGATLRRSIELATYI 189 Query: 185 KPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPP 244 N E + ++ D++ + + + ++++ G GA + Q+ Sbjct: 190 AVNDYEAKLVCDKTGWSEDEI---------ASRVQALIITRGEHGATIRHRDGTEQIPAV 240 Query: 245 PV-KSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQG--TRLCSHDDTQ 301 + G GD+ G + + R G+ +QG T + + Sbjct: 241 RAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQGPQTYAPTRAEID 300 Query: 302 KIYA 305 + Sbjct: 301 ARFE 304 >3GO6-A nrPDB Length = 310 Score = 72.6 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 58/290 (20%), Positives = 94/290 (32%), Gaps = 35/290 (12%) Query: 13 LDSATITPQIYPEG-KLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGE-HLV 70 +D + + G + + PGG G N A A A G G L Sbjct: 30 MDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGDDPAAAQLR 89 Query: 71 SLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIES 130 + L V + + V+AS E V PGA + + + Sbjct: 90 AHLRANAVGLDRTVTVPGPSGTAIIVVDASAENTVLVAPGANAHLTPVPSA------VAN 143 Query: 131 GAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNI-ELVKPNQK 189 +L+ +P V + + + +G+ S+ + I ++V N+ Sbjct: 144 CDVLLTQLEIP--VATALAAARAAQSADAVVMVNASPAGQDRSSLQDLAAIADVVIANEH 201 Query: 190 ELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQ 249 E + + V++LG +GA V ++ +V P V Sbjct: 202 EANDWPSPPT--------------------HFVITLGVRGARYVGADGVFEVPAPTVTPV 241 Query: 250 STVGAGDSMVGAMTLKLAEN----ASLEEMVRFGVAAGSAATLNQGTRLC 295 T GAGD G + N A +R AAG+ ATL G C Sbjct: 242 DTAGAGDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSGVGDC 291 >3LOO-A nrPDB Length = 365 Score = 71.8 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 42/287 (14%), Positives = 90/287 (31%), Gaps = 19/287 (6%) Query: 32 APVFEPGGGGIN---VARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVATVEAKD 87 + GG N VA+ I +A G L V V + Sbjct: 74 QAEYIAGGSVQNSLRVAQWILQRPRTAIFFGCVGQDEYARILEERATSNGVNVQYQRSAT 133 Query: 88 WTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISG---SLPPGV 144 V V + + A E + + ++ +SG ++ Sbjct: 134 SPTGTCAVLVTGTQRSLCANLAAANDFTPEHLRSDGNRAYLQGAQFFYVSGFFFTVSFES 193 Query: 145 KLEKLTQLISAAQKQGIRCIVDSSGEALSAALA--IGNIELVKPNQKELSALVNRELTQP 202 L + + + + + L ++++ N+ E AL Sbjct: 194 ALSVAKEAAATGRMFMMNLSAPFVPQFYKNNLEEIFPYVDVLFGNETEAIALAKEFNYGT 253 Query: 203 DDVRKAAQEIVNSGKA-----KRVVVSLGPQGALGVDS--ENCIQVVPPPV---KSQSTV 252 +D+R+ + I K + V+++ G L +++ +N + + + T Sbjct: 254 EDLREIGKRIAALPKENGKRKRIVIITQGSDPVLLIEAGTDNVREFPVQKLAPEQMVDTN 313 Query: 253 GAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDD 299 GAGD+ VG +L ++ +++ ++ G+ A G Sbjct: 314 GAGDAFVGGFLAQLLQSRTVDVCIKCGIWAAREIIQRSGCTFEGEPS 360 >2VAR-A nrPDB Length = 313 Score = 71.8 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 45/290 (15%), Positives = 103/290 (35%), Gaps = 21/290 (7%) Query: 34 VFEPGGGGINVARAIAHLGGSATAIFPAGGA-TGEHLVSLLADENVPVATVEAKDWTRQN 92 G +N A+ S + I G G++++ + + + ++ + + Sbjct: 29 EKHVAGSELNFCIAVVRNHLSCSLIARVGNDEFGKNIIEYSRAQGIDTSHIKVDNESFTG 88 Query: 93 LH-------VHVEASGEQYRFVMPGAALNEDE-FRQLEEQVLEIESGAILVISGSLPPGV 144 ++ + +++ YR G+ L+ ++ + S I + Sbjct: 89 IYFIQRGYPIPMKSELVYYRKGSAGSRLSPEDINENYVRNSRLVHSTGITLAISDNAKEA 148 Query: 145 KLEKLTQLISAAQKQGIRCIVDSS----GEALSAALAIGNIELVKPNQKELSALVNRELT 200 ++ S + IR + SS E + + L +IE++ + + L+ ++T Sbjct: 149 VIKAFELAKSRSLDTNIRPKLWSSLEKAKETILSILKKYDIEVLITDPDDTKILL--DVT 206 Query: 201 QPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVG 260 PD +A ++ G K ++ LG +GA+ V + GAGD+M G Sbjct: 207 DPD---EAYRKYKELG-VKVLLYKLGSKGAIAYKDNVKAFKDAYKVPVEDPTGAGDAMAG 262 Query: 261 AMTLKLAENASLEEMVRFGVAAGSA--ATLNQGTRLCSHDDTQKIYAYLS 308 + +E + G+AA + + +D ++ Sbjct: 263 TFVSLYLQGKDIEYSLAHGIAASTLVITVRGDNELTPTLEDAERFLNEFK 312 >4GM6-A nrPDB Length = 351 Score = 67.9 bits (164), Expect = 5e-12, Method: Composition-based stats. Identities = 49/274 (17%), Positives = 87/274 (31%), Gaps = 21/274 (7%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGAT-GEHLVSLLADENVPVATVEAKDWTRQNLHVH 96 GG NVA ++ LG G+ V L V A V ++ Sbjct: 56 GGAEANVAVNLSKLGHPTRIATVVPANPIGKMAVEHLWRHQVDTAFVVEAGDRLGTYYLE 115 Query: 97 VEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVK---LEKLTQLI 153 + + V + + ++ + E+ G ++ + + LE + ++I Sbjct: 116 SGTALKAPSVVYDRQHSSFARHKSMDWDLSELLKGIRVLHVSGITIALSTFWLEMVVKII 175 Query: 154 SAAQKQGIRCIVDSSGEALSAALA---------IGNIELVKPNQKELSALVNRELTQPDD 204 A++ GI+ D + A L + ++ Q + A D Sbjct: 176 REAKRNGIKISFDMNYRAKLWELEAAKRAYQQLLPLVDYCSAGQMDAVAFFEISSETTDY 235 Query: 205 VRKAAQEIVNSG---KAKRVVVSLGP---QGALGVDSENCIQVVPPPVKS-QSTVGAGDS 257 + + N KR V+S QG L E C + + VG GD+ Sbjct: 236 YQAMHDKYPNIELFYATKRTVISASHHLLQGHLWTQGE-CWESEEYAIYPIVDRVGGGDA 294 Query: 258 MVGAMTLKLAENASLEEMVRFGVAAGSAATLNQG 291 A+ + +E V+F AA G Sbjct: 295 YTAAVLHGILSEWRPDETVKFATAAAGLKHSIHG 328 >2AFB-A nrPDB Length = 351 Score = 66.0 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 46/298 (15%), Positives = 98/298 (32%), Gaps = 33/298 (11%) Query: 38 GGGGINVARAIAHLGGSATAIFPAGGAT-GEHLVSLLADENVPVATVEAKDWTRQNLHVH 96 GG NVA +A +G A + G+ L V + A+ R ++ Sbjct: 44 GGAEANVAAFLAQMGLDAYFVTKLPNNPLGDAAAGHLRKFGVKTDYI-ARGGNRIGIYFL 102 Query: 97 VEASGEQYRFVMPGAALN--EDEFRQLEEQVLEIESGAILVISGSLPP--GVKLEKLTQL 152 + ++ V+ A + + R+ + ++ SG PP L Sbjct: 103 EIGASQRPSKVVYDRAHSAISEAKREDFDWEKILDGARWFHFSGITPPLGKELPLILEDA 162 Query: 153 ISAAQKQGIRCIVDSSGEAL---------SAALAIGNIELVKPNQKELSALVNRELT--- 200 + A ++G+ D + A + ++++ N++++ ++ + Sbjct: 163 LKVANEKGVTVSCDLNYRARLWTKEEAQKVMIPFMEYVDVLIANEEDIEKVLGISVEGLD 222 Query: 201 ------QPDDVRKAAQEIVNSGKAKRVVVSLGPQ--------GALGVDSENCIQVVPPPV 246 + K A+E+ K V ++L + ++ + Sbjct: 223 LKTGKLNREAYAKIAEEVTRKYNFKTVGITLRESISATVNYWSVMVFENGQPHFSNRYEI 282 Query: 247 KSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLC-SHDDTQKI 303 VGAGDS GA+ ++ F AA G + S ++ +K+ Sbjct: 283 HIVDRVGAGDSFAGALIYGSLMGFDSQKKAEFAAAASCLKHTIPGDFVVLSIEEIEKL 340 >3LHX-A nrPDB Length = 319 Score = 65.2 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 52/287 (18%), Positives = 91/287 (31%), Gaps = 39/287 (13%) Query: 38 GGGGINVARAIAHLGGSATAI-----FPAGGATGEHLVSLLADENVPVATVEAKDWTRQN 92 GG +N + IA A + + ++ ENV + + + Sbjct: 29 GGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPG 88 Query: 93 LH-VHVEASGEQYRFVMPGAALNEDEFRQLEEQ----VLEIESGAILVISG---SLPPGV 144 L+ + +++GE+ +F EQ E+ + L +SG ++ Sbjct: 89 LYYIETDSTGERT--FYYWRNEAAAKFWLASEQSAAICEELANFDYLYLSGISLAILSPT 146 Query: 145 KLEKLTQLISAAQKQGIRCIVDS------------SGEALSAALAIGNIELVKPNQKELS 192 EKL L+ + +G + I D+ + + L +I + + ++ Sbjct: 147 SREKLLSLLRECRAKGGKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDA- 205 Query: 193 ALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALG-VDSENCIQVVP---PPVKS 248 L V N+G K VVV G L + E + V P K Sbjct: 206 ------LWGQQPVEDVIARTHNAG-VKEVVVKRGADSCLVSIAGEALVDVPAVKLPKEKV 258 Query: 249 QSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLC 295 T AGDS S E + G S +G + Sbjct: 259 IDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGAIIP 305 >3BF5-A nrPDB Length = 306 Score = 62.6 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 44/299 (14%), Positives = 84/299 (28%), Gaps = 31/299 (10%) Query: 13 LDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSL 72 +D I EG + GG N A G T +++ Sbjct: 31 IDVLISVDSIPREGSVNVKDLRPRFGGTAGNFAIVAQKFRIPFDLYSAVGMKTHREYLAM 90 Query: 73 LADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESG- 131 + + VE + + +Q F+ GA E + + +G Sbjct: 91 IESMGINTGHVEKFEDESGPICYIATDGKKQVSFMHQGAMAAWAPQLADEYEYVHFSTGP 150 Query: 132 AILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKEL 191 L ++ S+ + + ++ ++ + L I + + N E Sbjct: 151 NYLDMAKSIRSKIIFDPSQEIHKYSK------------DELKKFHEISYMSIF--NDHEY 196 Query: 192 SALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQST 251 V +V+ G +G+ P S T Sbjct: 197 RVFREMTGLSSPKV--------------TTIVTNGERGSSLFMDGKKYDFPAIP-SSGDT 241 Query: 252 VGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLC-SHDDTQKIYAYLSR 309 VGAGDS + L L S+E+ + +G + + +D ++ R Sbjct: 242 VGAGDSFRAGLYLALYNRRSIEKGMIYGTIIAHHVIDDGIENFSLNMEDLERETENYRR 300 >2AA0-A nrPDB Length = 383 Score = 60.6 bits (145), Expect = 9e-10, Method: Composition-based stats. Identities = 55/305 (18%), Positives = 101/305 (33%), Gaps = 50/305 (16%) Query: 20 PQIYPEGKLRCTAPVFEPGGGGINVARAIAHL---GGSATAIFPAGGAT-GEHLVSLLAD 75 Q+ L P PGG +N R + L GSA + G G+ L L Sbjct: 70 EQMRIYSTLDQFNPTSLPGGSALNSVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDK 129 Query: 76 ENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILV 135 E + + A + V + E+ GA + +L E SGA++ Sbjct: 130 EGLATRFMVAPGQSTGVCAVLINEK-ERTLCTHLGACGS----FRLPEDWTTFASGALIF 184 Query: 136 ISGSLPPGVKLEKLTQLISAAQKQGIRCI---------VDSSGEALSAALAIGNIELVKP 186 + + + ++ A V+ +A+ + L + ++ Sbjct: 185 YATAYTLTATPKNALEVAGYAHGIPNAIFTLNLSAPFCVELYKDAMQSLLL--HTNILFG 242 Query: 187 NQKELS--------------ALVNRELTQPDDVRKAAQEIVNSGK----AKRVVVSLG-- 226 N++E + AL +V A ++ +G+ K VV++ G Sbjct: 243 NEEEFAHLAKVHNLVAAEKTALSTANKEHAVEVCTGALRLLTAGQNTSATKLVVMTRGHN 302 Query: 227 --------PQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRF 278 G + V V + T GAGD+ VG L++ ++++ + Sbjct: 303 PVIAAEQTADGTVVVHEVGVPVVAAEKI--VDTNGAGDAFVGGFLYALSQGKTVKQCIMC 360 Query: 279 GVAAG 283 G A Sbjct: 361 GNACA 365 >3KTN-A nrPDB Length = 346 Score = 60.2 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 44/299 (14%), Positives = 89/299 (29%), Gaps = 33/299 (11%) Query: 39 GGGINVARAIAHLGGSATAIFPA-GGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHV 97 G G+N+ +AH I GE + L + V K + + Sbjct: 35 GTGVNLLANLAHFQLETALITKLPANRLGEAGKAALRKLGISDQWVGEKGDHIGSFFAEM 94 Query: 98 EASGEQYRFVMPGAALNEDEFRQLEEQVLE--IESGAILVISG---SLPPGVKLEKLTQL 152 + + + ++ E + ++ I G SL + + L Sbjct: 95 GYGIRPTQVTYQNRHQSAFGISEAKDYDFEAFLAEVDMVHICGISLSLTEKTR-DAALIL 153 Query: 153 ISAAQKQGIRCIVD----------SSGEALSAALA--IGNIELVKPNQKELSALVN---- 196 A + D +S + + ++V ++++L L+ Sbjct: 154 AQKAHAYQKKVCFDFNYRPSLNTANSALFMRQQYERILPYCDIVFGSRRDLVELLGFIPR 213 Query: 197 RELTQPDDVRKAAQEIVNSGKAKRVVVSLGP--------QGALGVDSENCIQVVPPPVKS 248 +L + Q ++ + + G L +E P + Sbjct: 214 EDLEGEAQETELIQRFMSQYNLEWFAGTTRSHSQNQNYLSGYLYTQNEYQQSEKRPLLN- 272 Query: 249 QSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGT-RLCSHDDTQKIYAY 306 +GAGD+ + ++N SLE+ V F G A QG L + + + Sbjct: 273 LDRIGAGDAYAAGILYGYSQNWSLEKAVTFATVNGVLAHTIQGDIPLTTVKQVNHVLEH 331 >1TD2-A nrPDB Length = 287 Score = 59.1 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 49/248 (19%), Positives = 89/248 (35%), Gaps = 36/248 (14%) Query: 59 FPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEF 118 AG + E + L P+ TV+ + G+ VMP + L E Sbjct: 15 GHAGNSAAEFPMRRLGANVWPLNTVQFS---------NHTQYGKWTGCVMPPSHLT--EI 63 Query: 119 RQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIR---------------C 163 Q + ++ + ++ SG L + E + ++ + + C Sbjct: 64 VQGIAAIDKLHTCDAVL-SGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHPEKGC 122 Query: 164 IVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVV 223 IV + +++ PN EL L + ++ AA+E++ G +V Sbjct: 123 IVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLVK 182 Query: 224 SLGPQG-------ALGVDSENCIQVVPPPVK--SQSTVGAGDSMVGAMTLKLAENASLEE 274 L G L V ++ + P V + VG GD G + +KL + A+L+E Sbjct: 183 HLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQE 242 Query: 275 MVRFGVAA 282 + AA Sbjct: 243 ALEHVTAA 250 >3UQ9-A nrPDB Length = 372 Score = 57.2 bits (136), Expect = 9e-09, Method: Composition-based stats. Identities = 40/297 (13%), Positives = 85/297 (28%), Gaps = 23/297 (7%) Query: 25 EGKLRCTAPVFEPGGGGINVARAIAHL---GGSATAIFPAGGAT-GEHLVSLLADENVPV 80 + + + GG +N + I + + + G G+++ + + ++ Sbjct: 70 DEIQKKKKLNYIAGGATLNTVKMIQWIIQKPFVCSYVGCIGADIQGKYIKNDCSALDLVT 129 Query: 81 AT-VEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGS 139 + + + V V + A + +E + I+G Sbjct: 130 EFQIAEEPLMTGKVAVLVSEKLRSMVTYLGAACDLSLAHIEQPHVWSLVEKAQVYYIAGF 189 Query: 140 LPPGVKLEKLTQLISAAQKQGIRCIVDSSG-----EALSAALAIGNIELVKPNQKELSAL 194 + L + + + + C S+ I +V N+ E A Sbjct: 190 VINTCYEGMLKIAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYSNIVFGNESEAEAY 249 Query: 195 VNRELTQPDDVRKAAQEIVNSGKAK------RVVVSLGPQGALGVDSENCIQVVPPPV-- 246 D V A+ I + A V+++ G + L + ++ V Sbjct: 250 GEVHGLLEDTVHATARYIADLPFADGKKRKRLVIITRG-KNPLLYTDSSDSEIHQFMVEQ 308 Query: 247 ----KSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDD 299 + T GAGD+ + + V A + G L S D Sbjct: 309 FKDDQIIDTNGAGDAFAAGFIADYIRGKPMITSLHAAVKAAAYIICRSGFSLGSRDS 365 >3PZS-A nrPDB Length = 289 Score = 57.2 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 45/117 (38%), Gaps = 9/117 (7%) Query: 175 ALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQG----- 229 A+ +++ PN EL L + + + A+ + G +V L G Sbjct: 136 NEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLVKHLSRAGYHADC 195 Query: 230 --ALGVDSENCIQVVPPPVK--SQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAA 282 L V +++ + P V + VG GD G + + L + L++ + AA Sbjct: 196 FEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLDKALEHVTAA 252 >4C5N-A nrPDB Length = 276 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 36/171 (21%), Positives = 62/171 (36%), Gaps = 10/171 (5%) Query: 131 GAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKE 190 I+ +G + + K + + EA+ + +V PN E Sbjct: 84 EEIIKRAGEVYEASNAQYFVVDPVMVCKGEDEVLNPGNTEAMI-KYLLPKATVVTPNLFE 142 Query: 191 LSALVNR-ELTQPDDVRKAAQEIVNSGKAKRVVVSLGP------QGALGVDSENCIQVVP 243 L +L +D++KAA I + G A+ V++ G L D + Q+ Sbjct: 143 AGQLSGLGKLNSIEDMKKAATIIFDKG-AQHVIIKGGKALDQDKSYDLYYDGQTFYQLTT 201 Query: 244 PPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRL 294 + GAG + A T LA S +E V A A+ + G ++ Sbjct: 202 DMFQQSYNHGAGCTFAAATTAYLANGKSPKEAVISA-KAFVASAIKNGWKM 251 >4JJP-A nrPDB Length = 267 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 70/201 (34%), Gaps = 17/201 (8%) Query: 92 NLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLE-----------IESGAILVISGSL 140 + V + + + V LN+ ++ E V E + S I++ Sbjct: 39 GMSVITAITAQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVEN 98 Query: 141 PPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELT 200 + L K G + + E L I ++ PN E + ++ Sbjct: 99 LKKYNPKYLVVDPVMISKSGYYLLKPEAKENLI-KYLIPLAYIITPNIPEAEEITGIKIH 157 Query: 201 QPDDVRKAAQEIVNSGKAKRVVVSLGP-QG---ALGVDSENCIQVVPPPVKSQSTVGAGD 256 DD+++ +EI+ G K V++ G G + V + ++T G G Sbjct: 158 NVDDMKRVGEEILQLGP-KFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGC 216 Query: 257 SMVGAMTLKLAENASLEEMVR 277 ++ A+T LA + E V Sbjct: 217 TLSSAITSYLALGYEITEAVN 237 >2I5B-A nrPDB Length = 271 Score = 52.2 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 9/121 (7%) Query: 163 CIVDSSGEALSAALAIGNIELVKPNQKELSALVNRE-LTQPDDVRKAAQEIVNSGKAKRV 221 + +AL LA ++ PN E S L + L DD+ +AA++I G A+ V Sbjct: 118 VLYPEHAQALREQLA-PLATVITPNLFEASQLSGMDELKTVDDMIEAAKKIHALG-AQYV 175 Query: 222 VVSLGPQ------GALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEM 275 V++ G + + D E + + + T GAG + A+T +LA+ A ++E Sbjct: 176 VITGGGKLKHEKAVDVLYDGETAEVLESEMIDTPYTHGAGCTFSAAVTAELAKGAEVKEA 235 Query: 276 V 276 + Sbjct: 236 I 236 >5YSQ-A nrPDB Length = 286 Score = 51.4 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 42/293 (14%), Positives = 94/293 (32%), Gaps = 21/293 (7%) Query: 17 TITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLADE 76 T + + + GGG + A + LG I S L D Sbjct: 3 TFIGHVSKDVNVVDGKREIAYGGGVVMGAITSSLLGVKTKVITKCTREDVSKF-SFLRDN 61 Query: 77 NVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVI 136 V V +++ T + + + E + +E + + I + Sbjct: 62 GVEVVFLKSPRTTSIENRYGSDPDTRESFLISAADPFTESDLAFIEGEAVHINP----LW 117 Query: 137 SGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGN-----IELVKPNQKEL 191 G P + +++ + V + + + + ++L K + +E Sbjct: 118 YGEFPEDLIPVLRRKVMFLSADAQGFVRVPENEKLVYRDWEMKEKYLKYLDLFKVDSREA 177 Query: 192 SALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQST 251 L +D+R++ + I + G +++++ G + D + + Sbjct: 178 ETLTG-----TNDLRESCRIIRSFGA--KIILATHASGVIVFDGN-FYEASFRSWSLEGR 229 Query: 252 VGAGDSMVGAMTLKLA-ENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKI 303 G GD+ A + + S+E+ +F A S + G +D + I Sbjct: 230 TGRGDTCTAAFLVGFVFKKMSIEKATKFAAAVTSVKMRHPGP--LRREDLEAI 280 >4S1M-A nrPDB Length = 287 Score = 49.5 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 42/113 (37%), Gaps = 10/113 (8%) Query: 178 IGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGV---- 233 I +++ PN ELS L E+ + KA + G ++V+ +G + Sbjct: 134 IKYADIITPNATELSFLTGLEVNSVSEAIKACHILHEQG-IPVILVTSIKEGNDIILLCS 192 Query: 234 ----DSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAA 282 + + P ++ G GD++ + + + LE V ++ Sbjct: 193 FKDTLNNKNFTIKIPRIEG-DFTGVGDTLTYILLSWIIKGIPLEHAVNRAIST 244 >1JXH-A nrPDB Length = 288 Score = 48.3 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 53/140 (37%), Gaps = 6/140 (4%) Query: 158 KQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGK 217 K G + S+ E L L + + L+ PN E +AL++ + + A + + Sbjct: 133 KSGDPLLSPSAIETLRVRL-LPQVSLITPNLPEAAALLDAPHARTEQEMLAQGRALLAMG 191 Query: 218 AKRVVVSLG-----PQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASL 272 + V++ G E + P V +++T G G ++ A+ + S Sbjct: 192 CEAVLMKGGHLEDAQSPDWLFTREGEQRFSAPRVNTKNTHGTGCTLSAALAALRPRHRSW 251 Query: 273 EEMVRFGVAAGSAATLNQGT 292 E V A SAA T Sbjct: 252 GETVNEAKAWLSAALAQADT 271 >5B6A-A nrPDB Length = 288 Score = 47.9 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 35/157 (22%), Positives = 59/157 (37%), Gaps = 12/157 (7%) Query: 158 KQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGK 217 ++G + S L A A+ + + PNQ EL + +R+ D + A+ ++ G Sbjct: 121 EKGCIVAPEVSDFLLEEAAAVA--DYLCPNQLELDSFCDRQPNSLADCVEMARSLLARGP 178 Query: 218 AKRVVVSL---GPQGA----LGVDSENCIQVVPPPVK-SQSTVGAGDSMVGAMTLKLAEN 269 +V L G G L V ++ + P + + VG GD G +L Sbjct: 179 RAILVKHLNYPGKAGDTFEMLLVAADQAWHLQRPLLAFPRQPVGVGDLASGLFLSRLLLG 238 Query: 270 ASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKIYAY 306 L F AA L T+ C + + + A Sbjct: 239 DDLRNAFEFTGAAVHEVLLE--TQACGSYELELVRAQ 273 >2DDM-A nrPDB Length = 283 Score = 47.5 bits (111), Expect = 7e-06, Method: Composition-based stats. Identities = 25/125 (20%), Positives = 43/125 (34%), Gaps = 11/125 (8%) Query: 159 QGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKA 218 GI D L + + PN EL L + D AA+ +++ Sbjct: 133 SGIYVKPDLPEAYRQYLLPLAQG--ITPNIFELEILTGKNCRDLDSAIAAAKSLLSD-TL 189 Query: 219 KRVVVSLGPQG-------ALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENAS 271 K VVV+ + V +++ + VK+ G GD + L + + Sbjct: 190 KWVVVTSASGNEENQEMQVVVVTADSVNVISHSRVKT-DLKGTGDLFCAQLISGLLKGKA 248 Query: 272 LEEMV 276 L + V Sbjct: 249 LTDAV 253 >4XF7-A nrPDB Length = 273 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 42/290 (14%), Positives = 93/290 (32%), Gaps = 32/290 (11%) Query: 17 TITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLADE 76 + + + + + GGG A A++ E + L Sbjct: 4 LVVGHVVRDIVKKGNKVLERLGGGAYYSALALSRFCDVEILTSF--SNLPEEWIKELE-- 59 Query: 77 NVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILV- 135 +A ++ + G + R L E E++ + E +L+ Sbjct: 60 --SMAKLQVVPSETTTTYELTYLDGNRRR-------LKLLERASPIEELPDGEY-DVLLM 109 Query: 136 --ISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSA 193 ++ +PP + L + VD G S++ + + + + Sbjct: 110 NPVAREVPPALVTSALKKFP--------FVAVDIQGFIRSSSPGEIQYQPIDGSFLKGVK 161 Query: 194 LVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVG 253 +++ +L + ++ + E V+ +++S GP+ P V + G Sbjct: 162 ILHADLGEYQYLQGFSPEFVD-----VLLLSNGPEPGKAFLHGREYTFEPVHVGVDESTG 216 Query: 254 AGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKI 303 AGD +GA T + ++ A + N+ S DD ++ Sbjct: 217 AGDVFLGAFT-GFYSQCPFVQALKRAAAFTALFLKNRSVDF-SMDDVNEL 264 >1UB0-A nrPDB Length = 258 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 6/109 (5%) Query: 178 IGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVS---LGPQGA--LG 232 +LV PN+ E AL+ R + + +AA+ ++ G K V++ L + A L Sbjct: 128 FPLADLVTPNRLEAEALLGRPIRTLKEAEEAAKALLALGP-KAVLLKGGHLEGEEAVDLL 186 Query: 233 VDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVA 281 ++ P V +++T G G ++ A+ LA+ L E V A Sbjct: 187 ATRGGVLRFSAPRVHTRNTHGTGCTLSAAIAALLAKGRPLAEAVAEAKA 235 >1YGJ-A nrPDB Length = 312 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 18/134 (13%), Positives = 43/134 (32%), Gaps = 18/134 (13%) Query: 154 SAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIV 213 + + D + + +++ PNQ E L R++ ++ + + Sbjct: 119 QRNGEGAMYVPDDLLPVYREKVVPVA--DIITPNQFEAELLTGRKIHSQEEALEVMDMLH 176 Query: 214 NSGKAKRVVVS---LGPQGALGVDSENCIQVVPPPVKSQST-------------VGAGDS 257 + G V+ S L P+G+ + + + P + VG GD Sbjct: 177 SMGPDTVVITSSNLLSPRGSDYLMALGSQRTRAPDGSVVTQRIRMEMHKVDAVFVGTGDL 236 Query: 258 MVGAMTLKLAENAS 271 + ++ + Sbjct: 237 FAAMLLAWTHKHPN 250 >5TRW-A nrPDB Length = 296 Score = 41.4 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 47/138 (34%), Gaps = 12/138 (8%) Query: 178 IGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQ--------G 229 G + + PN EL LV RE+ ++ A +E++ G K V+V Sbjct: 144 PGVADAMAPNHTELQRLVGREIETLEEAVTACRELIARGP-KLVLVKHLLDRNSPADRFN 202 Query: 230 ALGVDSENCIQVVPPPVK-SQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATL 288 L V P ++ VG GD + S+ +AA +A Sbjct: 203 MLVVTEREAWMGQRPLYPFARQPVGVGDLTSAVFVARTLLGDSIRAAFEHTLAAVNAVV- 261 Query: 289 NQGTRLCSHDDTQKIYAY 306 + T + + + A Sbjct: 262 -KATWQAGRYELELVAAQ 278 >4E69-A nrPDB Length = 328 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 38/252 (15%), Positives = 77/252 (30%), Gaps = 23/252 (9%) Query: 39 GGGINVARAIAHLGGSATAIFP--AGGA-TGEHLVSLLADENVPVATVEAKDWTRQNLHV 95 G N A +A L + + G + + + ++ + + L++ Sbjct: 51 GDTFNTAWYLARLRPESRISYFSAIGDDALSQQMRAAMSAAGIDGGGLRVIPGRTVGLYL 110 Query: 96 HVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISG---SLPPGVKLEKLTQL 152 GE+ G + + + + ++ SG ++ L + Sbjct: 111 ITLEQGERSFAYWRGQSAARELAGDADALAAAMARADVVYFSGITLAILDQCGRATLLRA 170 Query: 153 ISAAQKQGIRCIVD---------SSGEALSAALAIGNI-ELVKPNQKELSALVNRELTQP 202 ++ A+ G D +GE + + ++ P+ ++ +A Sbjct: 171 LAQARATGRTIAFDPNLRPRLWAGTGEMTETIMQGAAVSDIALPSFEDEAAWFGDAGPDA 230 Query: 203 DDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQ-STVGAGDSMVGA 261 R A + VVV GP + +V PPV T AGDS Sbjct: 231 TADRYA------RAGVRSVVVKNGPHAVHFLQDGRRGRVPVPPVAQVVDTTAAGDSFNAG 284 Query: 262 MTLKLAENASLE 273 + + LE Sbjct: 285 LLDSVLAGQPLE 296 >5ZWB-B nrPDB Length = 296 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 37/102 (36%), Gaps = 8/102 (7%) Query: 184 VKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGAL------GVDSEN 237 + PN EL L + ++ AAQ +++ K VV++ P +L V ++ Sbjct: 161 LTPNVFELEMLSGKPCRTLEEAVAAAQSLLSD-TLKWVVITSAPGESLETITVAVVTAQV 219 Query: 238 CIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFG 279 P V + G GD + + + L + Sbjct: 220 VEVFAHPRV-ATELKGTGDLFCAELVSGIVQGKKLTTAAKDA 260 >3MBJ-A nrPDB Length = 291 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 40/114 (35%), Gaps = 12/114 (10%) Query: 178 IGNIELVKPNQKELSALVNRELT---QPDDVRKAAQEIVNSGKAKRVVVSLGPQG----- 229 I +++ PN EL L++ +++++ + + + G ++ S+ Sbjct: 137 ITKADVITPNLTELFYLLDEPYKADSTDEELKEYLRLLSDKGPQVVIITSVPVHDEPHKT 196 Query: 230 ---ALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGV 280 A +V P + G GD+ +T L + SL + Sbjct: 197 SVYAYNRQGNRYWKVTCPYL-PAHYPGTGDTFTSVITGSLMQGDSLPMALDRAT 249 >5TQI-A nrPDB Length = 294 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 42/145 (28%), Gaps = 10/145 (6%) Query: 170 EALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQG 229 E + + PN EL L R + + A + ++ G +V L + Sbjct: 135 EEFIVNEMPALADGMSPNHTELQKLAGRRIETVAEAVDACRTLIARGPKIILVKHLHDRN 194 Query: 230 A-------LGVDSENCIQVVPPPVK-SQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVA 281 + L V P + VG GD + S+ +A Sbjct: 195 SPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAAFEHTLA 254 Query: 282 AGSAATLNQGTRLCSHDDTQKIYAY 306 A A + T + + I A Sbjct: 255 AVHAVV--KATYDARRYELELIAAQ 277 >2F7K-A nrPDB Length = 327 Score = 37.1 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 36/111 (32%), Gaps = 16/111 (14%) Query: 177 AIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLG---PQGALGV 233 + +++ PNQ E L R++ ++ + + + G V+ S PQG+ + Sbjct: 155 VVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYL 214 Query: 234 DSENCIQVVPPPVKSQST-------------VGAGDSMVGAMTLKLAENAS 271 + P VG GD + ++ + Sbjct: 215 IVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPN 265 >3ZS7-A nrPDB Length = 300 Score = 34.8 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 27/101 (26%), Gaps = 17/101 (16%) Query: 178 IGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLG----------- 226 + ++V PN E S L + AA N G A ++ S Sbjct: 140 VPLADIVTPNYFEASLLSGVTVNDLSSAILAADWFHNCGVAHVIIKSFREQENPTHLRFL 199 Query: 227 ---PQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTL 264 +G+ V + G GD + Sbjct: 200 YSVKEGSEAAVRRFSGVVPYHEGRY---TGTGDVFAACLLA 237 >3HYO-A nrPDB Length = 282 Score = 32.1 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 18/121 (14%), Positives = 34/121 (28%), Gaps = 5/121 (4%) Query: 178 IGNIELVKPNQKELSALVNRELTQPDDVR---KAAQEIVNSGKAKRVVVSLGPQ--GALG 232 I +++ PN E + L D+ A Q + +G + G Sbjct: 132 IQQADVILPNTTEAALLTGAPYQVTPDLEVILPALQAQLKTGAHAVITDVQRADQIGCAW 191 Query: 233 VDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGT 292 +D +Q G GD++ + L L + + A Sbjct: 192 LDEAGHVQYCGARRLPGHYNGTGDTLAAVIAGLLGRGYPLAPTLARANQWLNMAVAETIA 251 Query: 293 R 293 + Sbjct: 252 Q 252 >1J3W-A nrPDB Length = 163 Score = 31.4 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 24/57 (42%) Query: 228 QGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGS 284 +G + E PPP+ + +T+ AG++ KL A +E V G G Sbjct: 38 KGFVLAHKEALWAPKPPPLDTLATLVAGNAAATQALAKLLGEARFQEEVHQGERMGL 94 >3RMJ-A nrPDB Length = 370 Score = 31.4 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 33/237 (13%), Positives = 77/237 (32%), Gaps = 29/237 (12%) Query: 42 INVARAIAHLGGSATAIFPAGGATGEH-----LVSLLADENVPVATVEAKDWTRQNLHVH 96 I VAR + LG A + G+ + + V + + RQ Sbjct: 37 IRVARQLEKLGVDIIEAGFAAASPGDFEAVNAIAKTITKSTVCSLSRAIERDIRQAGEAV 96 Query: 97 VEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAA 156 A ++ + + ++ + +++ + + + + I+ T + + Sbjct: 97 APAPKKRIHTFIATSPIHMEYKLKMKPKQVIEAAVKAVKIARE---------YTDDVEFS 147 Query: 157 QKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSG 216 + +R +D E A + G + P+ + + + R+ + N G Sbjct: 148 CEDALRSEIDFLAEICGAVIEAGATTINIPD----TVGYSIPYKTEEFFRELIAKTPNGG 203 Query: 217 KAKRVV-----VSLGPQGALGVDSENCIQVVPPPVKSQSTVG--AGDSMVGAMTLKL 266 K + L +L QV + + +G AG++ V + + L Sbjct: 204 KVVWSAHCHNDLGLAVANSLAALKGGARQVEC----TVNGLGERAGNASVEEIVMAL 256 >5EIY-B nrPDB Length = 729 Score = 31.0 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 53/159 (33%), Gaps = 7/159 (4%) Query: 96 HVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISA 155 V + + GA D + ++ ++ + + + ++ G + ++A Sbjct: 154 LVTIEAQHRHRIYCGADAEFDLWTEV-----DLSQSGVALPAAAI--GTEPTSFIAALTA 206 Query: 156 AQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNS 215 + G + + A L L +P E L + + A+ + Sbjct: 207 QAESGRPVEIRTPTPPDEATLRTLAQALGRPLPDEALPLALSKPWSAETGPTYARITLLP 266 Query: 216 GKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGA 254 A RV + G GA+ + E+ + P +GA Sbjct: 267 SDADRVSIRRGGDGAVVLVLEHPPEGSPNASLVADLLGA 305 >3IC9-A nrPDB Length = 492 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 35/107 (32%), Gaps = 10/107 (9%) Query: 9 LAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGG----- 63 LA + ++ L + VF PG G+ + +A++ LG +G Sbjct: 154 LAAAGSRLLTNDNLFELNDLPKSVAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQ 213 Query: 64 --ATGEHLVSLLADE---NVPVATVEAKDWTRQNLHVHVEASGEQYR 105 + +E + + + ++ + SG++ Sbjct: 214 DEEMKRYAEKTFNEEFYFDAKARVISTIEKEDAVEVIYFDKSGQKTT 260 >4YL5-A nrPDB Length = 263 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 20/136 (14%) Query: 175 ALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLG-------P 227 I L+ PN EL AL D+ +A Q++ G AK V+V G Sbjct: 134 VELIPLATLITPNTVELRALTGVT-----DLDQATQKLFEMG-AKAVLVKGGHEDTPDFI 187 Query: 228 QGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVR------FGVA 281 + +L +D E P ++ G+G S+ + +LA SL+ V+ FGV Sbjct: 188 KNSLYIDGELAASSTCPRLEG-EYHGSGCSLASFIAGRLALGDSLKIAVQHAETWLFGVL 246 Query: 282 AGSAATLNQGTRLCSH 297 + + G ++ Sbjct: 247 KNAETPVLNGQKIPKR 262 >5JFQ-A nrPDB Length = 322 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 20/170 (11%), Positives = 46/170 (27%), Gaps = 20/170 (11%) Query: 15 SATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLA 74 + + PEG R + GG + + L A + + Sbjct: 20 IEELLKEQEPEGLYRAARHYLKAGGKRLRPVITL--LSAEALGEDYRKAIHAAIAIETVH 77 Query: 75 DENVPVATVEAKDWTRQNLHVHVEASGEQYRFVM----------------PGAALNEDEF 118 + + + +D R+ + G + Sbjct: 78 NFTLVHDDIMDEDEMRRGVKTVHTLFGIPTAILAGDTLYAEAFEILSMSDAPPENIVRAV 137 Query: 119 RQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSS 168 +L +EI G + +S V + +++ +K G+ + +S Sbjct: 138 SKLARVCVEICEGQFMDMSFEERDSVGESEYLEMVR--KKTGVLIGISAS 185 >4BJP-A nrPDB Length = 511 Score = 28.7 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 5/61 (8%) Query: 13 LDSATITPQIYPEGKLRCTAPVFE----PGGGGINVARAIAHLGGSATAIFPAGGATGEH 68 +D +++PE +R + E PGGGG+ A + G G + Sbjct: 383 VDPPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPD-GRY 441 Query: 69 L 69 + Sbjct: 442 I 442 >4KXX-A nrPDB Length = 637 Score = 27.9 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 40/254 (15%), Positives = 81/254 (31%), Gaps = 24/254 (9%) Query: 10 APSLDSATIT-PQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEH 68 APS+D A I P + A G +A+A LG ++ I G T Sbjct: 293 APSVDIANIRMPSLPSYKVGDKIATRKAYG-------QALAKLGHASDRIIALDGDTKNS 345 Query: 69 LVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPG--AALNEDEFRQLEEQVL 126 S + + P +E + + + V + AA F Q+ + Sbjct: 346 TFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIR--MA 403 Query: 127 EIESGAILVISGSLPPGVKLEKLTQLI--SAAQKQGIR---CIVDSSGEALSAALAIGN- 180 I I + + + +Q+ A + + S G A A+ + Sbjct: 404 AISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAAN 463 Query: 181 ---IELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSEN 237 I ++ ++ E + + N D A+ ++ S + V+ G + + Sbjct: 464 TKGICFIRTSRPENAIIYN---NNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAE 520 Query: 238 CIQVVPPPVKSQST 251 ++ ++ Sbjct: 521 LLKKEKINIRVLDP 534 >4PR3-A nrPDB Length = 233 Score = 27.1 bits (58), Expect = 8.8, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 41/108 (37%), Gaps = 4/108 (3%) Query: 198 ELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDS 257 + ++ A + +G +V+SLG G+ + QV + G Sbjct: 60 PVEAAVNLASALAHLKLAGDMPDLVISLGSAGSAKLPQAEVYQVSSVSYRDMDASPIG-- 117 Query: 258 MVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKIYA 305 +T L ++E + F VA A+L+ G + S ++I A Sbjct: 118 FEKGVTPFLDLPETVE--LPFRVAGIDTASLSTGGNIVSGKAYERIEA 163 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.119 0.260 Lambda K H 0.267 0.0365 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,412,938 Number of Sequences: 36641 Number of extensions: 290348 Number of successful extensions: 1075 Number of sequences better than 10.0: 88 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 48 Number of HSP's that attempted gapping in prelim test: 851 Number of HSP's gapped (non-prelim): 161 length of query: 309 length of database: 10,336,785 effective HSP length: 97 effective length of query: 212 effective length of database: 6,782,608 effective search space: 1437912896 effective search space used: 1437912896 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 58 (27.1 bits)