BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P06865 (529 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2GJX-A nrPDB 1051 0.0 2GK1-I nrPDB 910 0.0 1O7A-A nrPDB 608 e-174 2GK1-N nrPDB 327 6e-90 1NP0-C nrPDB 244 8e-65 5Y0V-A nrPDB 211 5e-55 5OAR-B nrPDB 209 3e-54 6EZS-A nrPDB 164 9e-41 6JEB-A nrPDB 153 2e-37 6Q63-A nrPDB 140 1e-33 3RCN-A nrPDB 133 2e-31 4PYS-A nrPDB 125 4e-29 3SUR-A nrPDB 119 2e-27 4C7D-A nrPDB 108 7e-24 1HP5-A nrPDB 104 1e-22 1QBA-A nrPDB 86 4e-17 5BXR-A nrPDB 60 2e-09 1YHT-A nrPDB 57 3e-08 5MI4-A nrPDB 42 5e-04 3EMC-A nrPDB 37 0.025 2YL9-A nrPDB 31 1.2 6BSV-A nrPDB 29 4.6 3PNU-A nrPDB 29 5.1 4BT1-A nrPDB 28 7.0 4FGM-A nrPDB 28 8.8 3IF8-A nrPDB 28 9.0 >2GJX-A nrPDB Length = 507 Score = 1051 bits (2718), Expect = 0.0, Method: Compositional matrix adjust. Identities = 506/507 (99%), Positives = 507/507 (100%) Query: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPY 82 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPY Sbjct: 1 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPY 60 Query: 83 LTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETF 142 LTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETF Sbjct: 61 LTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETF 120 Query: 143 SQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFH 202 SQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFH Sbjct: 121 SQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFH 180 Query: 203 WHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGH 262 WHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGH Sbjct: 181 WHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGH 240 Query: 263 TLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGD 322 TLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGD Sbjct: 241 TLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGD 300 Query: 323 EVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVK 382 EVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVK Sbjct: 301 EVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVK 360 Query: 383 IQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAF 442 IQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFY+VEPLAF Sbjct: 361 IQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAF 420 Query: 443 EGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSH 502 EGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSH Sbjct: 421 EGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSH 480 Query: 503 FRCELLRRGVQAQPLNVGFCEQEFEQT 529 FRCELLRRGVQAQPLNVGFCEQEFEQT Sbjct: 481 FRCELLRRGVQAQPLNVGFCEQEFEQT 507 >2GK1-I nrPDB Length = 440 Score = 910 bits (2351), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/440 (99%), Positives = 440/440 (100%) Query: 89 TLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWK 148 TLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWK Sbjct: 1 TLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWK 60 Query: 149 SAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD 208 SAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD Sbjct: 61 SAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD 120 Query: 209 PSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP 268 PSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP Sbjct: 121 PSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP 180 Query: 269 GIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTC 328 GIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTC Sbjct: 181 GIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTC 240 Query: 329 WKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTI 388 WKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTI Sbjct: 241 WKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTI 300 Query: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAFEGTPEQ 448 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFY+VEPLAFEGTPEQ Sbjct: 301 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQ 360 Query: 449 KALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL 508 KALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL Sbjct: 361 KALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL 420 Query: 509 RRGVQAQPLNVGFCEQEFEQ 528 RRGVQAQPLNVGFCEQEFEQ Sbjct: 421 RRGVQAQPLNVGFCEQEFEQ 440 >1O7A-A nrPDB Length = 515 Score = 608 bits (1567), Expect = e-174, Method: Compositional matrix adjust. Identities = 287/504 (56%), Positives = 364/504 (72%), Gaps = 4/504 (0%) Query: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRP 81 ALWP P + + + L P NF + +S A P C++L+EAF+RY +FG W Sbjct: 14 ALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHE 73 Query: 82 YLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLET 141 + T + +LV + C+ P + S E+YTL + + +L + VWGALRGLET Sbjct: 74 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLET 133 Query: 142 FSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVF 201 FSQLV++ + GTF IN++ I D PRF HRG+L+DTSRHYLP+ IL TLD MA+NK NV Sbjct: 134 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVL 193 Query: 202 HWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPG 261 HWH+VDD SFPY+S TFPEL KGSY+ ++H+YT DV+ VIEYARLRGIRVL EFDTPG Sbjct: 194 HWHIVDDQSFPYQSITFPELSNKGSYS-LSHVYTPNDVRMVIEYARLRGIRVLPEFDTPG 252 Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGG 321 HTLSWG G LLTPCYS +FGP+NP+LN TY F++TFF E+S VFPD ++HLGG Sbjct: 253 HTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGG 312 Query: 322 DEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKV 381 DEV+F CW+SNP+IQDFMR+KGFG DFK+LESFYIQ +LDI+++ KG +VWQEVFD+K Sbjct: 313 DEVEFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKA 372 Query: 382 KIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLA 441 K+ P TI++VW++ Y +EL VT +GF +LSAPWYL+ ISYG DW+ +Y VEPL Sbjct: 373 KLAPGTIVEVWKDSA---YPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 429 Query: 442 FEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLS 501 F GT +QK L IGGEAC+WGEYVD TNL PRLWPRA AV ERLWS+K D+ AY+RL+ Sbjct: 430 FGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLT 489 Query: 502 HFRCELLRRGVQAQPLNVGFCEQE 525 RC ++ RG+ AQPL G+C E Sbjct: 490 RHRCRMVERGIAAQPLYAGYCNHE 513 >2GK1-N nrPDB Length = 237 Score = 327 bits (839), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 147/237 (62%), Positives = 187/237 (78%), Gaps = 3/237 (1%) Query: 286 TFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFG 345 +FGP+NP+LN TY F++TFF E+S VFPD ++HLGGDEV+F CW+SNP+IQDFMR+KGFG Sbjct: 3 SFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFG 62 Query: 346 EDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELE 405 DFK+LESFYIQ +LDI+++ KG +VWQEVFD+K K+ P TI++VW++ Y +EL Sbjct: 63 TDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSA---YPEELS 119 Query: 406 LVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVD 465 VT +GF +LSAPWYL+ ISYG DW+ +Y VEPL F GT +QK L IGGEAC+WGEYVD Sbjct: 120 RVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTQKQKQLFIGGEACLWGEYVD 179 Query: 466 NTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFC 522 TNL PRLWPRA AV ERLWS+K D+ AY+RL+ RC ++ RG+ AQPL G+C Sbjct: 180 ATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLTRHRCRMVERGIAAQPLYAGYC 236 >1NP0-C nrPDB Length = 190 Score = 244 bits (623), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 116/188 (61%), Positives = 142/188 (75%), Gaps = 1/188 (0%) Query: 92 KNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE 151 + +LV + C+ P + S E+YTL + + +L + VWGALRGLETFSQLV++ + Sbjct: 4 QQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQDSY 63 Query: 152 GTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSF 211 GTF IN++ I D PRF HRG+L+DTSRHYLP+ IL TLD MA+NK NV HWH+VDD SF Sbjct: 64 GTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSF 123 Query: 212 PYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIP 271 PY+S TFPEL KGSY+ ++H+YT DV+ VIEYARLRGIRVL EFDTPGHTLSWG G Sbjct: 124 PYQSITFPELSNKGSYS-LSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQK 182 Query: 272 GLLTPCYS 279 LLTPCYS Sbjct: 183 DLLTPCYS 190 >5Y0V-A nrPDB Length = 578 Score = 211 bits (538), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 160/504 (31%), Positives = 250/504 (49%), Gaps = 55/504 (10%) Query: 60 VLDEAFQRYRD---LLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLP-TLESVEN 115 +++ A +R+++ L GS P+ LTGK + V +V N+ +LE E+ Sbjct: 78 LMEAAAKRFKEQVSLAIPRGSTPK--LTGK-------AVDVYLVNENPNEKAFSLEMDES 128 Query: 116 YTLTINDDQCLLLSETV-----WGALRGLETFSQLVW--KSAEGTFFINKTEIEDFPRFP 168 Y L ++ ++ T+ +G GLET SQL + + I D P +P Sbjct: 129 YGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYP 188 Query: 169 HRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYN 228 +RG+LLDT+R+Y + SI T++ MA KLN HWH+ D SFP+ + P L + G+ + Sbjct: 189 YRGILLDTARNYYSIESIKRTIEAMAAVKLNTDHWHITDSQSFPFVTTKRPNLYKFGALS 248 Query: 229 PVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGL-LTPCYSGSEPSGTF 287 P +YT ++EV+ + RG+RVL EFD P H G G LT C+ +EP ++ Sbjct: 249 P-QKVYTKAAIREVVRFGLERGVRVLPEFDAPAHV---GEGWQDTDLTVCFK-AEPWKSY 303 Query: 288 ------GPVNPSLNNTYEFMSTFFLEVSSVF--PDFYLHLGGDEVDFTCWKSNPEIQDFM 339 G +NP+ + Y+++ + +++ VF D + H+GGDEV CW S+ IQ+FM Sbjct: 304 CVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIF-HMGGDEVSEACWNSSDSIQNFM 362 Query: 340 RKKGFG---EDFKQLESFYIQTLLDIV-SSYGKG--YVVWQEVFDNKVKI-----QPDTI 388 + + E F +L +++ Q D ++GK ++W N I + D I Sbjct: 363 MQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYI 422 Query: 389 IQVWREDIPVNYMKELE---LVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAFEGT 445 IQVW + LE + + + AL Y + G +W YI ++ + Sbjct: 423 IQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNS 482 Query: 446 P-----EQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERL 500 P E + V+GGEA +W E D + L RLWPRA A+AERLW+ TS Y R+ Sbjct: 483 PAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEY-RM 541 Query: 501 SHFRCELLRRGVQAQPLNVGFCEQ 524 H R +R G+QA+ L +C Q Sbjct: 542 LHIRERFVRMGIQAESLQPEWCYQ 565 >5OAR-B nrPDB Length = 499 Score = 209 bits (531), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 145/479 (30%), Positives = 232/479 (48%), Gaps = 85/479 (17%) Query: 114 ENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKSAEGTFFINK-TEIEDFPRFPHR 170 E+YTL + +D + +ETVWGAL T QLV G I + I+D P +P+R Sbjct: 25 ESYTLDVEEDSDTITINAETVWGALHAFTTLQQLVISDGHGGLIIEEPVNIKDSPLYPYR 84 Query: 171 GLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPV 230 G++LDT R+++ L I + L+ M+ +KLNV HWH+ D S+P +PE M K +Y+P Sbjct: 85 GIMLDTGRNFVSLPKIFEQLEGMSLSKLNVLHWHIDDAQSWPIWVDVYPE-MVKDAYSP- 142 Query: 231 THIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLS-WGPGIPGLLT-----------PCY 278 IY+ DV+ ++ YAR RGIRV+ E D P H+ S W P ++T P + Sbjct: 143 HEIYSRNDVRNIVNYARARGIRVIPEIDMPSHSSSGWKQVDPEMVTCTDSWWSNDDWPLH 202 Query: 279 SGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDF 338 + EP+ G ++ N TYE + + E+S +FPD + H+GGDE+ C+ + + Sbjct: 203 TAVEPNP--GQLDIIYNKTYEVVGNVYKELSDIFPDHWFHVGGDEIQPNCFNFSTHV--- 257 Query: 339 MRKKGFGED----FKQLESFYIQTLLDIVSSYG--KGYVVWQEV---FDNKVKIQPDTII 389 K F ED + L +++ + I +Y + V+W+++ DN + + ++ Sbjct: 258 --TKWFAEDPSRTYHDLAQYWVDHAVPIFQNYSQERRLVMWEDIALSADNAHDVPKNIVM 315 Query: 390 QVWREDIPVNYMKELELVTKAGFRALLSAPWYL---------------NRISYGPD---- 430 Q W N ++ + +T G+ ++S+ +L + PD Sbjct: 316 QSWN-----NGLEYISNLTARGYDVIVSSSDFLYLDCGHGGFVTNDPRYNVMANPDANTP 370 Query: 431 -----------------WKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRL 473 W+ Y + T Q +IG A +WGE VD+ N+ Sbjct: 371 NFNYGGNGGSWCAPYKTWQRIYDYD-FTLNLTETQAKHIIGATAPLWGEQVDDINVSSMF 429 Query: 474 WPRAGAVAERLWS-------NKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCEQE 525 WPRA A+AE +WS NK T+++T +R+ +FR L+ GVQAQ L +C Q Sbjct: 430 WPRAAALAELVWSGNRDANGNKRTTEMT---QRILNFREYLVANGVQAQALVPKYCLQH 485 >6EZS-A nrPDB Length = 652 Score = 164 bits (415), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 120/430 (27%), Positives = 204/430 (47%), Gaps = 47/430 (10%) Query: 108 PTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKS-AEGTFFINKTEIEDFPR 166 PTL+ Y L ++++ + + + G T QL+ + A T I D PR Sbjct: 204 PTLDE-GAYKLKVSEESIKIEAGSSSGFTHACATLLQLLKRDEATKTMEAVCCSIIDSPR 262 Query: 167 FPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGS 226 F +RG++LD +RH+ + + ++++A+ KLN FHWHL DD + E + P+L G+ Sbjct: 263 FRYRGMMLDCARHFHSVEQVKRLINLLAHYKLNTFHWHLTDDEGWRVEIKSLPQLTEIGA 322 Query: 227 YNPV--------THI-------YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIP 271 + + TH+ YT +++++VI +A RGI ++ E D PGH + +P Sbjct: 323 WRGIDETIEPQYTHLSQRYGGFYTQEEIRDVIAFAEQRGITIIPEIDVPGHCRAAIKSLP 382 Query: 272 GLLTPCYSGSEPSG----TFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFT 327 LL +E +NP+L +YEF+ E++++FP Y+H+G DEV Sbjct: 383 HLLIEAEDTTEYRSIQHYNDNVINPALPGSYEFIDKVLEEIAALFPAPYVHIGADEVPNG 442 Query: 328 CWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDT 387 W +P Q M + G+ D+K+L+ +++ D + GK + W+E + K+ DT Sbjct: 443 VWSKSPACQALMEQLGY-TDYKELQGHFLRHAEDKLRKLGKRMLGWEEA-QHGNKVSKDT 500 Query: 388 IIQVW-REDIPVNYMKELELVTKAGFRALL--SAPWYLNRIS-YGP-----DWKD----- 433 +I W E+ +N + GF +L + YL+ Y P DW + Sbjct: 501 VIYSWLSEEAALN-------CARQGFDVVLQPAQTTYLDMTQDYAPEEPGVDWANPLPLE 553 Query: 434 -FYIVEPLA-FEGTPEQKALVIGGEACMWGEYVDN-TNLVPRLWPRAGAVAERLWSNKLT 490 Y EPLA + + G + +W E ++N + + ++PR A+AE W+ K Sbjct: 554 KAYNYEPLAEVPADDPIRKRIWGIQTALWCEIINNPSRMDYMIFPRLTAMAEACWTEKQH 613 Query: 491 SDLTFAYERL 500 D T RL Sbjct: 614 RDWTDYLSRL 623 >6JEB-A nrPDB Length = 469 Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 128/458 (27%), Positives = 212/458 (46%), Gaps = 40/458 (8%) Query: 79 PRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRG 138 P P T R K + ++S ++PTLE+ + Y LT+ L S G + G Sbjct: 8 PEPSRTELRQETAKTLQLLSD-----QEVPTLET-DAYRLTVTPQGAHLASGGREGRIYG 61 Query: 139 LETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKL 198 L T QL + A I I D PR+P RGL++D +RH++P + + +D+MAY K Sbjct: 62 LATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARHFIPAADLKKFVDMMAYYKF 121 Query: 199 NVFHWHLVDDPSFPYESFTFPELM-----RKGSYN---PVTHIYTAQDVKEVIEYARLRG 250 N H HL D+ + +P+L R+ S+ P +YT Q++KE++ Y RG Sbjct: 122 NRLHLHLTDNQGWRLPVPGYPKLKSVASRREESFGDGIPHEGMYTKQELKELVAYCAARG 181 Query: 251 IRVLAEFDTPGHTLSWGPGIPGLL---TPCYSGSEPSGTFGP-VNPSLNNTYEFMSTFFL 306 I V+ E D PGH + P P + +G V P ++F ++ F Sbjct: 182 IDVIPEIDMPGHNQALHAAYPEFFCFPKPDMNVRTTAGNSKELVCPQKPEVWKFYASVFN 241 Query: 307 EVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSY 366 E+ +FP +HLGGDE W+ P ++ + ++ +Q+++F+ +T +++ Sbjct: 242 ELKDIFPSGIVHLGGDEAPTELWEKCPLCREARTRAAMKDEQEQMKAFFAKTAA-LLAKN 300 Query: 367 GKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWY----L 422 G+ W E N P + WR+ ++ +E KAG ++++ Y Sbjct: 301 GQTPQFWYE--GNAGIYHPGETVYAWRQG---QALQSIEKTKKAGLNLIMASSEYCYLDF 355 Query: 423 NRISYGPDW--------KDFYIVEPLAFEGTPEQKALVIGG-EACMWGEYVDNTN-LVPR 472 +I +W + Y ++P AF G PE++A I G A +W E + + N L+ R Sbjct: 356 PQIQGQRNWGWMKTTTLQKCYDLDP-AF-GKPEKEAGHIRGVHAPVWAERLPDLNHLLYR 413 Query: 473 LWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRR 510 +PRA A+AE WS +L+ R +L+R Sbjct: 414 AYPRACAIAEAGWSPMGVRSWENFRRKLADHRQFILKR 451 >6Q63-A nrPDB Length = 774 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 112/445 (25%), Positives = 200/445 (44%), Gaps = 56/445 (12%) Query: 84 TGKRHTLE-----KNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRG 138 TGK ++E KN +V+++ + +E+ E+Y L + D + + T G G Sbjct: 78 TGKDFSIEAGTEGKNAIVLALGS-------EVENPESYQLKVTDQGVTITAPTEAGVFYG 130 Query: 139 LETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKL 198 ++T + + + + EI+D PRF +RG D SRH+ + + +D++A + + Sbjct: 131 IQTLRKSLPIALGADVALPAVEIKDAPRFGYRGAHFDVSRHFFTIDEVKTYIDMLALHNM 190 Query: 199 NVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHI---------------YTAQDVKEVI 243 N HWH+ DD + E +P+L GS T I YT + KE++ Sbjct: 191 NRLHWHITDDQGWRLEIKKYPKLTEIGSQRSGTVIGRNSGEYDNTPYGGFYTQEQAKEIV 250 Query: 244 EYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGS-EPSGTFGPVNPSL----NNTY 298 +YA R I V+ E D PGH L+ P L C G E +G + L + Sbjct: 251 DYAAERYITVVPEIDLPGHMLAALAAYPEL--GCTGGPYEVWRQWGVADDVLCAGNDQVL 308 Query: 299 EFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDF-----KQLES 353 +F+ + E+ +FP Y+H+GGDE W+ P+ Q ++ G D ++L+S Sbjct: 309 KFLEDVYGELIEIFPSEYIHVGGDECPKVRWEKCPKCQARIKALGLKSDKNHSKEERLQS 368 Query: 354 FYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWRED---IPVNYMKELELVTKA 410 F I + ++ +G+ + W E+ + + P+ + WR + I K ++T Sbjct: 369 FVINHIEKFLNDHGRQIIGWDEILEG--GLAPNATVMSWRGESGGIEAAKQKHDVIMTPN 426 Query: 411 GF--------RALLSAPWYLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGEACMWGE 462 + + + P+ + Y P + Y EP+ TP+++ + G +A +W E Sbjct: 427 TYLYFDYYQAKDTENEPFGIG--GYLP-MERVYSYEPMPASLTPDEQQYIKGVQANLWTE 483 Query: 463 YVDN-TNLVPRLWPRAGAVAERLWS 486 Y+ ++ + PR A+ E WS Sbjct: 484 YIATFSHAQYMVLPRWAALCEVQWS 508 >3RCN-A nrPDB Length = 543 Score = 133 bits (335), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 113/402 (28%), Positives = 184/402 (45%), Gaps = 50/402 (12%) Query: 156 INKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYES 215 + + +ED PRF +RG +LD +RH++P ++L ++VMA +KLNV H HL DD + + Sbjct: 127 VPRVSVEDKPRFGYRGTMLDVARHFMPKDNVLRFIEVMAMHKLNVLHLHLTDDQGWRMQI 186 Query: 216 FTFPELMRKGSY----------------NPVTHIYTAQDVKEVIEYARLRGIRVLAEFDT 259 +P+L G++ P YT D++E++ +A R I V+ E D Sbjct: 187 NRYPKLTETGAWRRESSLGSWRAGVFDGRPHGGFYTQDDLREIVAFAADRHITVIPEIDV 246 Query: 260 PGHTLSWGPGIPGLLTPCYSGSEPS------GTFGPVNPSLNNTYEFMSTFFLEVSSVFP 313 PGH+ + P L GS P G V + EF EV +FP Sbjct: 247 PGHSQAAIAAYPELGAGPADGSSPVEVWTRWGINETVLEVSETSLEFYRNVLDEVVEIFP 306 Query: 314 DFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVW 373 ++ LGGDEV T W+++ + Q + G +D L S+++ L + +G+ VW Sbjct: 307 SPWISLGGDEVPLTQWQASAQAQAKAAELGL-DDVSGLHSWFVGQLALHLKHHGRATSVW 365 Query: 374 QEVFDNKVKIQPD-TIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYL---NRISYGP 429 E+ D + PD ++ WR Y ++ + K G+ ++ L +R + G Sbjct: 366 DEIGDGGL---PDGALVASWR-----GYEGGIDALRK-GYDVVMCPEHKLYLDHRQADGD 416 Query: 430 D----------WKDFYIVEPL-AFEGTPEQKALVIGGEACMWGEYVDNTNLVP-RLWPRA 477 D + Y EPL EGT + ++G +A +W E++D+ V +PR Sbjct: 417 DEPVPVGFVTTLQAVYEFEPLPGVEGT-DFPGRLLGAQANIWSEHLDSPRRVQFAAFPRL 475 Query: 478 GAVAERLWSNKLTSDLTFAYERLSHFRCELLRR-GVQAQPLN 518 A++E WSN D RL+ L GV+ +PL+ Sbjct: 476 SAISEVFWSNPAGRDYDEFLTRLTGAHLARLEAMGVEYRPLS 517 >4PYS-A nrPDB Length = 506 Score = 125 bits (315), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 103/399 (25%), Positives = 179/399 (44%), Gaps = 27/399 (6%) Query: 107 LPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINK-TEIEDFP 165 LPT E Y + + ++ ++ + G + +++ Q W + E I EI DFP Sbjct: 75 LPT----EGYRIRVTPERIIVEAADDAGFIYAIQSLRQ--WNTGEERGLIFPCVEITDFP 128 Query: 166 RFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKG 225 R R +LD+ R Y +S+I +D+ + K+N FHWHL + + E +P L R G Sbjct: 129 RVKWRSFMLDSGRQYQKVSTIKKYIDMASMLKMNYFHWHLTEGLGWRIEIKRYPFLTRIG 188 Query: 226 SY---NPVTH-IYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGS 281 ++ P Y+ ++VKE+I YA RGI V+ E D PGH + P L + Sbjct: 189 AFVGQGPEQQGFYSQEEVKEIIGYAADRGITVVPEIDMPGHAEAALNAYPRLGCFNVAVK 248 Query: 282 EPSGTF--GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFM 339 P F ++T F+ EV +FP Y+HLGGDE W P+ + + Sbjct: 249 VPQSGFTQNIFCAGKDSTLIFLKNVLDEVCRMFPSAYIHLGGDEAPKGNWDKCPDCRSRI 308 Query: 340 RKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVW------R 393 K+ +D L+ ++ + D + G+ + W +V PD ++ W R Sbjct: 309 EKEKL-KDSHDLQLWFSARMADYLKQKGRKAIFWGDVIYKDGYSLPDNVVIQWWNWRGHR 367 Query: 394 EDIPVNYMKE-LELVTKAGFRALLS---APWYLNRISYGPDWKDFYIVEPLAFEGTPEQK 449 + N ++ ++ + L+ PW + D +D Y+ P E+ Sbjct: 368 DLALKNAVRHNYPVICGTNYYTYLNFPLTPWKGYTQARTFDLEDVYLRNPSY--RPREEN 425 Query: 450 ALVIGGEACMW-GEYVDNTNLVPRLWPRAGAVAERLWSN 487 L++G + +W + V + + R++PR A+AE++W + Sbjct: 426 PLILGMSSALWTDDGVTESMIDRRVFPRILALAEQMWHS 464 >3SUR-A nrPDB Length = 525 Score = 119 bits (299), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 111/431 (25%), Positives = 184/431 (42%), Gaps = 55/431 (12%) Query: 114 ENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFIN-------KTEIEDFPR 166 E Y L +Q L + G RG +T QL+ E ++ + I D P Sbjct: 122 EGYDLITTSNQVTLTANKPEGVFRGNQTLLQLLPAGIEKNTVVSGVQWVIPHSNISDKPE 181 Query: 167 FPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGS 226 + +RGL+LD +RH+ + + +D+ + K+N FH HL DD + E ++P+L+ GS Sbjct: 182 YEYRGLMLDVARHFFTVDEVKRQIDLASQYKINKFHMHLSDDQGWRIEIKSWPDLIEIGS 241 Query: 227 YNPVTHI----YTAQDVKEVIEYARLRGIRVLAEFDTPGHT----LSWGPGIPGLLTPCY 278 V YT + K+++ YA R I V+ E D PGHT S+G P Sbjct: 242 KGQVGGGPGGYYTQEQFKDIVSYAAERYIEVIPEIDMPGHTNAALASYGELNPDGKRKAM 301 Query: 279 SGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDF 338 G + + P TY+F+ E++++ P Y+HLGGDE + T Sbjct: 302 RTDTAVG-YSTLMPRAEITYQFVEDVISELAAISPSPYIHLGGDESNATS---------- 350 Query: 339 MRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPV 398 D+ ++ + I +SYGK V W + D D+++Q W Sbjct: 351 ------AADY----DYFFGRVTAIANSYGKKVVGW-DPSDTSSGATSDSVLQNWTCSAST 399 Query: 399 NYMKELELVTKAGFRALLS-APWYLNRISY-----GPDWKDFYIVEPLAFEGTPE---QK 449 + + G + ++S A YL+ Y G W+ F + A+ P + Sbjct: 400 GTAAKAK-----GMKVIVSPANAYLDMKYYSDSPIGLQWRGF-VNTNRAYNWDPTDCIKG 453 Query: 450 ALVIGGEACMWGE-YVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL 508 A + G E+ +W E +V +L L+P+ + AE W+ + + ERL L Sbjct: 454 ANIYGVESTLWTETFVTQDHLDYMLYPKLLSNAEVGWTARGDRNWDDFKERLIEHTPRLQ 513 Query: 509 RRGVQ--AQPL 517 +G++ A P+ Sbjct: 514 NKGIKFFADPI 524 >4C7D-A nrPDB Length = 494 Score = 108 bits (269), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 106/411 (25%), Positives = 171/411 (41%), Gaps = 59/411 (14%) Query: 114 ENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE------GTFFINKTEIEDFPRF 167 E Y L + + + G G++T QL+ + E G + + IED PR+ Sbjct: 80 EGYRLDSGREGVTITARKAAGLFHGVQTLRQLLPAAVEKDSAQPGPWLVAGGTIEDTPRY 139 Query: 168 PHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSY 227 R +LD SRH+ + + +D +A K N H H+ DD + ++P L G Sbjct: 140 AWRSAMLDVSRHFFSVDEVKRYIDRVALYKYNKLHLHISDDQGWRLAIDSWPRLATYGGS 199 Query: 228 -----NPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHT----LSWGP-GIPGLLTPC 277 P H YT D +E++ YA R + V+ E D PGHT S+ G+ P Sbjct: 200 TEVGGGPGGH-YTKADYEEIVRYAASRHLEVVPEIDMPGHTNAALASYAELNCDGVAPPL 258 Query: 278 YSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQD 337 Y+G++ F + + TY+F+ E++++ P YLH+GGDE S P+ D Sbjct: 259 YTGTKVG--FSTLCVDKDVTYDFVDDVLGELAALTPGRYLHIGGDEA-----HSTPQ-AD 310 Query: 338 FMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIP 397 F+ +++ + IV+ YGK V W ++ + ++Q W D Sbjct: 311 FV--------------AFMKRVQPIVAKYGKTVVGWHQL--AGAEPVEGALVQYWGLDRT 354 Query: 398 VNYMKELELVTKAGFRALLSAPW--------YLNRISYGPDWKDFYIV------EPLAF- 442 + K L+ +P Y G W + V +P A+ Sbjct: 355 SDAEKAQVAAAARNGTGLILSPADRTYLDMKYTKDTPLGLSWAGYVEVRRSYDWDPAAYL 414 Query: 443 EGTPEQKALVIGGEACMWGEYVDNTNLVPRL-WPRAGAVAERLWSNKLTSD 492 G P + V G EA +W E + + + + + +PR VAE WS T D Sbjct: 415 PGAPAEA--VRGVEAPLWTETLSDPDQLDFMAFPRLPGVAELGWSPASTHD 463 >1HP5-A nrPDB Length = 512 Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 105/410 (25%), Positives = 167/410 (40%), Gaps = 57/410 (13%) Query: 114 ENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE------GTFFINKTEIEDFPRF 167 E Y L + + G G++T QL+ + E G + + IED PR+ Sbjct: 98 EGYRLDSGPAGVTITARKAAGLFHGVQTLRQLLPPAVEKDSAQPGPWLVAGGTIEDTPRY 157 Query: 168 PHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSY 227 R +LD SRH+ + + +D +A K N H HL DD + ++P L G Sbjct: 158 AWRSAMLDVSRHFFGVDEVKRYIDRVARYKYNKLHLHLSDDQGWRIAIDSWPRLATYGGS 217 Query: 228 NPV----THIYTAQDVKEVIEYARLRGIRVLAEFDTPGHT----LSWGP-GIPGLLTPCY 278 V YT + KE++ YA R + V+ E D PGHT S+ G+ P Y Sbjct: 218 TEVGGGPGGYYTKAEYKEIVRYAASRHLEVVPEIDMPGHTNAALASYAELNCDGVAPPLY 277 Query: 279 SGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDF 338 +G++ F + + TY+F+ E++++ P YLH+GGDE S P+ DF Sbjct: 278 TGTKVG--FSSLCVDKDVTYDFVDDVIGELAALTPGRYLHIGGDEA-----HSTPK-ADF 329 Query: 339 MRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPV 398 + +++ + IV+ YGK V W ++ + ++Q W D Sbjct: 330 V--------------AFMKRVQPIVAKYGKTVVGWHQL--AGAEPVEGALVQYWGLDRTG 373 Query: 399 NYMKELELVTKAGFRALLSAPW--------YLNRISYGPDWKDFYIVE------PLAF-E 443 + K L+ +P Y G W + V+ P + Sbjct: 374 DAEKAEVAEAARNGTGLILSPADRTYLDMKYTKDTPLGLSWAGYVEVQRSYDWDPAGYLP 433 Query: 444 GTPEQKALVIGGEACMWGEYVDNTNLVPRL-WPRAGAVAERLWSNKLTSD 492 G P V G EA +W E + + + + + +PR VAE WS T D Sbjct: 434 GAPADA--VRGVEAPLWTETLSDPDQLDYMAFPRLPGVAELGWSPASTHD 481 >1QBA-A nrPDB Length = 858 Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 82/332 (24%), Positives = 132/332 (39%), Gaps = 74/332 (22%) Query: 116 YTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLD 175 Y L I + ++ G GL++ LV ++G+ I + D PRFP+RG+ LD Sbjct: 262 YELKIGKKEAQVIGFDQAGVFYGLQSILSLV--PSDGSGKIATLDASDAPRFPYRGIFLD 319 Query: 176 TSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGS--------- 226 +R++ ++L LD MA KLN FH+HL DD + E PEL G Sbjct: 320 VARNFHKKDAVLRLLDQMAAYKLNKFHFHLSDDEGWRIEIPGLPELTEVGGQRCHDLSET 379 Query: 227 ------YNPVTHIY----TAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPG---- 272 Y +Y + QD ++I+YA+ R I V+ E D P H + + Sbjct: 380 TCLLPQYGQGPDVYGGFFSRQDYIDIIKYAQARQIEVIPEIDMPAHARAAVVSMEARYKK 439 Query: 273 --------------LLTPCYSGSEPSGTF----GPVNPSLNNTYEFMSTFFLEVSSVF-- 312 L+ P + + S F +NP L+++ F+ E++ + Sbjct: 440 LHAAGKEQEANEFRLVDPTDTSNTTSVQFFNRQSYLNPCLDSSQRFVDKVIGEIAQMHKE 499 Query: 313 ---PDFYLHLGGDEVDFT------CWKSNPE-------------------IQDFMRKKGF 344 P H GGDE K+ PE + M K+G Sbjct: 500 AGQPIKTWHFGGDEAKNIRLGAGYTDKAKPEPGKGIIDQGNEDKPWAKSQVCQTMIKEGK 559 Query: 345 GEDFKQLESFYIQTLLDIVSSYGKGYV-VWQE 375 D + L S++ Q + +V ++G + WQ+ Sbjct: 560 VADMEHLPSYFGQEVSKLVKAHGIDRMQAWQD 591 >5BXR-A nrPDB Length = 644 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 68/283 (24%), Positives = 111/283 (39%), Gaps = 21/283 (7%) Query: 114 ENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLL 173 E + L I ++ T G G + SQ++ +G + + P++ RG Sbjct: 110 EGFKLNIGSKGLEVIGATDIGVFYGTRSVSQML---RQGQLTLPAGTVATKPKYKERGAT 166 Query: 174 LDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHI 233 L + + I L MA +LN + L++ P E T +K + Sbjct: 167 LCACQINISTDWIDRFLSDMADLRLN---YVLLEMKLKPEEDNT-----KKAA---TWSY 215 Query: 234 YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPS 293 YT DVK+ ++ A GI V+ E ++PGH W P SG + NP Sbjct: 216 YTRDDVKKFVKKANNYGIDVIPEINSPGHMNVWLENYPEYQLADNSGRKDPNKLDISNPE 275 Query: 294 LNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDF-TCWKSNPEIQDFMRKK-GFGEDFKQL 351 +F T E VF Y H+G DE T + + +++ F K+ G G Sbjct: 276 ---AVKFYKTLIDEYDGVFTTKYWHMGADEYMIGTSFDNYSKLKTFAEKQYGAGATPNDA 332 Query: 352 ESFYIQTLLDIVSSYGKGYVVWQE--VFDNKVKIQPDTIIQVW 392 + +I + V + GK +W + V V + D +I+ W Sbjct: 333 FTGFINDIDKYVKAKGKQLRIWNDGIVNTKNVSLNKDIVIEYW 375 >1YHT-A nrPDB Length = 367 Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 85/193 (44%), Gaps = 20/193 (10%) Query: 171 GLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELM------RK 224 GL+LD +RH+ I +D ++ + N H H D ++ ES + + Sbjct: 20 GLMLDIARHFYSPEVIKSFIDTISLSGGNFLHLHFSDHENYAIESHLLNQRAENAVQGKD 79 Query: 225 GSY-NPVTH--IYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCY-SG 280 G Y NP T + + + ++ YA+ +GI ++ E D+P H + + Y G Sbjct: 80 GIYINPYTGKPFLSYRQLDDIKAYAKAKGIELIPELDSPNHMTAIFKLVQKDRGVKYLQG 139 Query: 281 SEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDF--YLHLGGDEVDFTCWKSNPE---- 334 + ++ + ++ FM + EV +F D + H+GGDE ++ +SN E Sbjct: 140 LKSRQVDDEIDITNADSITFMQSLMSEVIDIFGDTSQHFHIGGDEFGYSV-ESNHEFITY 198 Query: 335 ---IQDFMRKKGF 344 + F+ KKG Sbjct: 199 ANKLSYFLEKKGL 211 >5MI4-A nrPDB Length = 727 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 29/178 (16%) Query: 83 LTGKRHTLEKNVLVVSVVTPG-------CNQLPTLESVENYTLTINDDQCLLLSETVWGA 135 L+GK+ + K +++S+ G Q+P + E Y L++N+ + +L G Sbjct: 56 LSGKQSS--KKGMLISIGEKGDKSVRKYSRQIP--DHKEGYYLSVNEKEIVLAGNDERGT 111 Query: 136 LRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAY 195 L+TF+QL+ +G + + EI+D+P +RG++ + L L Sbjct: 112 YYALQTFAQLL---KDGK--LPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGK 166 Query: 196 NKLNVFHWHLVDDP-------SFPY---ESFTFPELMRKGSYNPVT---HIYTAQDVK 240 NK+N + + DDP PY E+ EL+ + N V I+ QD+K Sbjct: 167 NKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDIK 224 >3EMC-A nrPDB Length = 331 Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 6/72 (8%) Query: 213 YESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPG 272 Y S T M+ +P H YT + E++++A RGI V GHTL W P Sbjct: 37 YNSVTAENQMKFEEVHPREHEYTFEAADEIVDFAVARGIGV------RGHTLVWHNQTPA 90 Query: 273 LLTPCYSGSEPS 284 + SG S Sbjct: 91 WMFEDASGGTAS 102 >2YL9-A nrPDB Length = 457 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 28/122 (22%), Positives = 51/122 (41%), Gaps = 24/122 (19%) Query: 165 PRFPH-------RGLLLDTSRHYLPLSS---ILDTLDVMAYNKLNVFHWH-----LVDDP 209 PR H + + +D R Y L+ I+D + Y+ +++ + L+DD Sbjct: 16 PRGSHMEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDM 75 Query: 210 SFPYESFTFPELMRKGSYNPVTHIY---------TAQDVKEVIEYARLRGIRVLAEFDTP 260 + T+ K + T Y T +V E+IEYA+ + I ++ ++P Sbjct: 76 TITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP 135 Query: 261 GH 262 GH Sbjct: 136 GH 137 >6BSV-A nrPDB Length = 338 Score = 29.3 bits (64), Expect = 4.6, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 11/59 (18%) Query: 205 LVDDPSFPYESFTFPELMR---------KGSYNPVTHIYTAQDVKEVIEYARLRGIRVL 254 L +PSFP +F P R K NPV Y + +K I+Y R+ GI + Sbjct: 19 LKQNPSFP--NFVAPNKPRVLLVTGSAPKPCENPVGDHYLLKSIKNKIDYCRIHGIEIF 75 >3PNU-A nrPDB Length = 359 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 30/83 (36%), Gaps = 13/83 (15%) Query: 64 AFQRYRDLLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVEN-------- 115 AF Y ++FGS S P P T + V V+ P +L S E Sbjct: 249 AFSGYEKVMFGSDSAPHPKDTKECCGCAAGVFSAPVILPVLAELFKQNSSEENLQKFLSD 308 Query: 116 -----YTLTINDDQCLLLSETVW 133 Y L +D+ L L E W Sbjct: 309 NTCKIYDLKFKEDKILTLEEKEW 331 >4BT1-A nrPDB Length = 73 Score = 28.5 bits (62), Expect = 7.0, Method: Composition-based stats. Identities = 13/24 (54%), Positives = 15/24 (62%) Query: 400 YMKELELVTKAGFRALLSAPWYLN 423 Y KE+E TK+ LLS PWY N Sbjct: 21 YAKEVEGFTKSAQELLLSYPWYGN 44 >4FGM-A nrPDB Length = 597 Score = 28.1 bits (61), Expect = 8.8, Method: Compositional matrix adjust. Identities = 22/100 (22%), Positives = 42/100 (42%), Gaps = 12/100 (12%) Query: 133 WGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDV 192 WG R + + L+ + F I IE+F + L+ + RHY S I L Sbjct: 152 WGCFRA-DNYDALI----DYPFLIGDLTIEEFIAHGIKHSLVLSGRHYADTSRITADLAK 206 Query: 193 MAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTH 232 + ++++F P++S+TF ++ + + H Sbjct: 207 ICETQISLFE-------EAPFQSYTFLTMVVGNGFGGLEH 239 >3IF8-A nrPDB Length = 339 Score = 28.1 bits (61), Expect = 9.0, Method: Compositional matrix adjust. Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 20/161 (12%) Query: 182 PLSSILDTLDVMAYN-------KLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIY 234 PL S+ + L+ A + K N + DP F YE+ +L+ KG NP+ +I Sbjct: 2 PLGSMWERLNCAAEDFYSRLLQKFNEEKKGIRKDP-FLYEADVQVQLISKGQPNPLKNIL 60 Query: 235 TAQDVKEVIEYARLRG-----IRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGP 289 D+ ++E L I L +T S G + L P + G + Sbjct: 61 NENDIVFIVEKVPLEKEETSHIEELQSEETAISDFSTGENVGPLALPVGKARQLIGLYTM 120 Query: 290 V-NPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCW 329 NP++ + L V++ P ++ + + TCW Sbjct: 121 AHNPNMTHL-----KINLPVTA-LPPLWVRCDSSDPEGTCW 155 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2GJX-A nrPDB 765 0.0 1O7A-A nrPDB 673 0.0 2GK1-I nrPDB 642 0.0 5Y0V-A nrPDB 443 e-125 6JEB-A nrPDB 434 e-122 6Q63-A nrPDB 432 e-121 6EZS-A nrPDB 417 e-117 4PYS-A nrPDB 398 e-111 5OAR-B nrPDB 394 e-110 3SUR-A nrPDB 392 e-109 1HP5-A nrPDB 378 e-105 4C7D-A nrPDB 378 e-105 3RCN-A nrPDB 367 e-102 2GK1-N nrPDB 319 2e-87 1QBA-A nrPDB 287 7e-78 5BXR-A nrPDB 273 1e-73 1NP0-C nrPDB 255 3e-68 1YHT-A nrPDB 180 1e-45 5MI4-A nrPDB 138 6e-33 Sequences not found previously or not previously below threshold: 2YLL-A nrPDB 102 4e-22 2YL9-A nrPDB 84 1e-16 2EPK-X nrPDB 61 9e-10 5A6B-D nrPDB 60 3e-09 3EMC-A nrPDB 38 0.011 6FHE-A nrPDB 36 0.057 1L8N-A nrPDB 34 0.18 2D73-A nrPDB 34 0.24 1LQS-L nrPDB 33 0.25 4DIK-A nrPDB 33 0.39 5M7S-A nrPDB 32 0.44 3W26-A nrPDB 32 0.57 2XSA-A nrPDB 32 0.60 5OT1-A nrPDB 31 1.0 4ML9-A nrPDB 31 1.0 5GNE-A nrPDB 31 1.1 1WZ2-A nrPDB 31 1.1 2A1L-A nrPDB 31 1.2 1WKB-A nrPDB 31 1.2 1TJ7-A nrPDB 31 1.4 3QQQ-A nrPDB 31 1.5 4W8I-A nrPDB 30 2.5 1YKN-B nrPDB 30 2.5 5H2T-A nrPDB 30 3.0 1SVV-A nrPDB 29 4.9 5C70-A nrPDB 29 5.3 1B5E-A nrPDB 29 7.5 >2GJX-A nrPDB Length = 507 Score = 765 bits (1975), Expect = 0.0, Method: Composition-based stats. Identities = 506/507 (99%), Positives = 507/507 (100%) Query: 23 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPY 82 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPY Sbjct: 1 LWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPY 60 Query: 83 LTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETF 142 LTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETF Sbjct: 61 LTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETF 120 Query: 143 SQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFH 202 SQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFH Sbjct: 121 SQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFH 180 Query: 203 WHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGH 262 WHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGH Sbjct: 181 WHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGH 240 Query: 263 TLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGD 322 TLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGD Sbjct: 241 TLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGD 300 Query: 323 EVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVK 382 EVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVK Sbjct: 301 EVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVK 360 Query: 383 IQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAF 442 IQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFY+VEPLAF Sbjct: 361 IQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAF 420 Query: 443 EGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSH 502 EGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSH Sbjct: 421 EGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSH 480 Query: 503 FRCELLRRGVQAQPLNVGFCEQEFEQT 529 FRCELLRRGVQAQPLNVGFCEQEFEQT Sbjct: 481 FRCELLRRGVQAQPLNVGFCEQEFEQT 507 >1O7A-A nrPDB Length = 515 Score = 673 bits (1737), Expect = 0.0, Method: Composition-based stats. Identities = 287/504 (56%), Positives = 364/504 (72%), Gaps = 4/504 (0%) Query: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRP 81 ALWP P + + + L P NF + +S A P C++L+EAF+RY +FG W Sbjct: 14 ALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHE 73 Query: 82 YLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLET 141 + T + +LV + C+ P + S E+YTL + + +L + VWGALRGLET Sbjct: 74 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLET 133 Query: 142 FSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVF 201 FSQLV++ + GTF IN++ I D PRF HRG+L+DTSRHYLP+ IL TLD MA+NK NV Sbjct: 134 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVL 193 Query: 202 HWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPG 261 HWH+VDD SFPY+S TFPEL KGSY+ ++H+YT DV+ VIEYARLRGIRVL EFDTPG Sbjct: 194 HWHIVDDQSFPYQSITFPELSNKGSYS-LSHVYTPNDVRMVIEYARLRGIRVLPEFDTPG 252 Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGG 321 HTLSWG G LLTPCYS +FGP+NP+LN TY F++TFF E+S VFPD ++HLGG Sbjct: 253 HTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGG 312 Query: 322 DEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKV 381 DEV+F CW+SNP+IQDFMR+KGFG DFK+LESFYIQ +LDI+++ KG +VWQEVFD+K Sbjct: 313 DEVEFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKA 372 Query: 382 KIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLA 441 K+ P TI++VW++ Y +EL VT +GF +LSAPWYL+ ISYG DW+ +Y VEPL Sbjct: 373 KLAPGTIVEVWKDSA---YPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 429 Query: 442 FEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLS 501 F GT +QK L IGGEAC+WGEYVD TNL PRLWPRA AV ERLWS+K D+ AY+RL+ Sbjct: 430 FGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLT 489 Query: 502 HFRCELLRRGVQAQPLNVGFCEQE 525 RC ++ RG+ AQPL G+C E Sbjct: 490 RHRCRMVERGIAAQPLYAGYCNHE 513 >2GK1-I nrPDB Length = 440 Score = 642 bits (1657), Expect = 0.0, Method: Composition-based stats. Identities = 439/440 (99%), Positives = 440/440 (100%) Query: 89 TLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWK 148 TLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWK Sbjct: 1 TLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWK 60 Query: 149 SAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD 208 SAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD Sbjct: 61 SAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD 120 Query: 209 PSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP 268 PSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP Sbjct: 121 PSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP 180 Query: 269 GIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTC 328 GIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTC Sbjct: 181 GIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTC 240 Query: 329 WKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTI 388 WKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTI Sbjct: 241 WKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTI 300 Query: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAFEGTPEQ 448 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFY+VEPLAFEGTPEQ Sbjct: 301 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYVVEPLAFEGTPEQ 360 Query: 449 KALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL 508 KALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL Sbjct: 361 KALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL 420 Query: 509 RRGVQAQPLNVGFCEQEFEQ 528 RRGVQAQPLNVGFCEQEFEQ Sbjct: 421 RRGVQAQPLNVGFCEQEFEQ 440 >5Y0V-A nrPDB Length = 578 Score = 443 bits (1139), Expect = e-125, Method: Composition-based stats. Identities = 171/566 (30%), Positives = 264/566 (46%), Gaps = 67/566 (11%) Query: 3 SSRLWFSLLLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNFQFQYDVSS------AAQP 56 SS SL F LWP P T + NF + +++S Sbjct: 23 SSEPALSLEACKMFCNEYGLLWPRP----TGEADL----GNFLSKINLNSIEVKILKKGA 74 Query: 57 GCSVLDEAFQRYRD---LLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLP-TLES 112 +++ A +R+++ L GS P+ LTGK + V +V N+ +LE Sbjct: 75 TDDLMEAAAKRFKEQVSLAIPRGSTPK--LTGK-------AVDVYLVNENPNEKAFSLEM 125 Query: 113 VENYTLTINDDQC-----LLLSETVWGALRGLETFSQLV--WKSAEGTFFINKTEIEDFP 165 E+Y L ++ + + + +G GLET SQL + + I D P Sbjct: 126 DESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKP 185 Query: 166 RFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKG 225 +P+RG+LLDT+R+Y + SI T++ MA KLN HWH+ D SFP+ + P L + G Sbjct: 186 VYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTDHWHITDSQSFPFVTTKRPNLYKFG 245 Query: 226 SYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPG-LLTPCYSGSEPS 284 + +P +YT ++EV+ + RG+RVL EFD P H G G LT C+ EP Sbjct: 246 ALSP-QKVYTKAAIREVVRFGLERGVRVLPEFDAPAHV---GEGWQDTDLTVCFKA-EPW 300 Query: 285 GTF------GPVNPSLNNTYEFMSTFFLEVSSVF-PDFYLHLGGDEVDFTCWKSNPEIQD 337 ++ G +NP+ + Y+++ + +++ VF H+GGDEV CW S+ IQ+ Sbjct: 301 KSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQN 360 Query: 338 FMRKKGF---GEDFKQLESFYIQTLLDIV-SSYGKG--YVVWQEVFDNKVKI-----QPD 386 FM + + E F +L +++ Q D ++GK ++W N I + D Sbjct: 361 FMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDD 420 Query: 387 TIIQVWREDIPVNYMKELE---LVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAFE 443 IIQVW + LE + + + AL Y + G +W YI ++ Sbjct: 421 YIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYD 480 Query: 444 GTP-----EQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYE 498 +P E + V+GGEA +W E D + L RLWPRA A+AERLW+ TS Y Sbjct: 481 NSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEY- 539 Query: 499 RLSHFRCELLRRGVQAQPLNVGFCEQ 524 R+ H R +R G+QA+ L +C Q Sbjct: 540 RMLHIRERFVRMGIQAESLQPEWCYQ 565 >6JEB-A nrPDB Length = 469 Score = 434 bits (1115), Expect = e-122, Method: Composition-based stats. Identities = 120/457 (26%), Positives = 204/457 (44%), Gaps = 38/457 (8%) Query: 79 PRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRG 138 P P T R K + ++S ++PTLE+ Y LT+ L S G + G Sbjct: 8 PEPSRTELRQETAKTLQLLSD-----QEVPTLETD-AYRLTVTPQGAHLASGGREGRIYG 61 Query: 139 LETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKL 198 L T QL + A I I D PR+P RGL++D +RH++P + + +D+MAY K Sbjct: 62 LATLRQLRDQLAGQPEGIPCGVITDKPRYPWRGLMVDPARHFIPAADLKKFVDMMAYYKF 121 Query: 199 NVFHWHLVDDPSFPYESFTFPELMRKGSYN--------PVTHIYTAQDVKEVIEYARLRG 250 N H HL D+ + +P+L S P +YT Q++KE++ Y RG Sbjct: 122 NRLHLHLTDNQGWRLPVPGYPKLKSVASRREESFGDGIPHEGMYTKQELKELVAYCAARG 181 Query: 251 IRVLAEFDTPGHTLSWGPGIPGLLT---PCYSGSEPSGTFGPV-NPSLNNTYEFMSTFFL 306 I V+ E D PGH + P P + +G + P ++F ++ F Sbjct: 182 IDVIPEIDMPGHNQALHAAYPEFFCFPKPDMNVRTTAGNSKELVCPQKPEVWKFYASVFN 241 Query: 307 EVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSY 366 E+ +FP +HLGGDE W+ P ++ + ++ +Q+++F+ +T +++ Sbjct: 242 ELKDIFPSGIVHLGGDEAPTELWEKCPLCREARTRAAMKDEQEQMKAFFAKTAA-LLAKN 300 Query: 367 GKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWY----L 422 G+ W E N P + WR+ ++ +E KAG ++++ Y Sbjct: 301 GQTPQFWYE--GNAGIYHPGETVYAWRQG---QALQSIEKTKKAGLNLIMASSEYCYLDF 355 Query: 423 NRISYGPDW--------KDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNT-NLVPRL 473 +I +W + Y ++P AF ++ + G A +W E + + +L+ R Sbjct: 356 PQIQGQRNWGWMKTTTLQKCYDLDP-AFGKPEKEAGHIRGVHAPVWAERLPDLNHLLYRA 414 Query: 474 WPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRR 510 +PRA A+AE WS +L+ R +L+R Sbjct: 415 YPRACAIAEAGWSPMGVRSWENFRRKLADHRQFILKR 451 >6Q63-A nrPDB Length = 774 Score = 432 bits (1111), Expect = e-121, Method: Composition-based stats. Identities = 122/516 (23%), Positives = 209/516 (40%), Gaps = 66/516 (12%) Query: 25 PWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPYLT 84 P PQ TS N F + V G + Q D L T Sbjct: 33 PLPQEIVTSQ------VNPFILKSGVKILYPEGNEKMQRNAQFLADYL--------KTAT 78 Query: 85 GKRHTLE-----KNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGL 139 GK ++E KN +V+++ + +E+ E+Y L + D + + T G G+ Sbjct: 79 GKDFSIEAGTEGKNAIVLALGSE-------VENPESYQLKVTDQGVTITAPTEAGVFYGI 131 Query: 140 ETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLN 199 +T + + + + EI+D PRF +RG D SRH+ + + +D++A + +N Sbjct: 132 QTLRKSLPIALGADVALPAVEIKDAPRFGYRGAHFDVSRHFFTIDEVKTYIDMLALHNMN 191 Query: 200 VFHWHLVDDPSFPYESFTFPELMRKGSYN---------------PVTHIYTAQDVKEVIE 244 HWH+ DD + E +P+L GS P YT + KE+++ Sbjct: 192 RLHWHITDDQGWRLEIKKYPKLTEIGSQRSGTVIGRNSGEYDNTPYGGFYTQEQAKEIVD 251 Query: 245 YARLRGIRVLAEFDTPGHTLSWGPGIPGLLT--PCYSGSEPSGT-FGPVNPSLNNTYEFM 301 YA R I V+ E D PGH L+ P L Y G + + +F+ Sbjct: 252 YAAERYITVVPEIDLPGHMLAALAAYPELGCTGGPYEVWRQWGVADDVLCAGNDQVLKFL 311 Query: 302 STFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQ-----LESFYI 356 + E+ +FP Y+H+GGDE W+ P+ Q ++ G D L+SF I Sbjct: 312 EDVYGELIEIFPSEYIHVGGDECPKVRWEKCPKCQARIKALGLKSDKNHSKEERLQSFVI 371 Query: 357 QTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWR---EDIPVNYMKELELVTKAGF- 412 + ++ +G+ + W E+ + + P+ + WR I K ++T + Sbjct: 372 NHIEKFLNDHGRQIIGWDEILEGG--LAPNATVMSWRGESGGIEAAKQKHDVIMTPNTYL 429 Query: 413 -------RALLSAPWYLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVD 465 + + P+ + Y P + Y EP+ TP+++ + G +A +W EY+ Sbjct: 430 YFDYYQAKDTENEPFGIG--GYLP-MERVYSYEPMPASLTPDEQQYIKGVQANLWTEYIA 486 Query: 466 N-TNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERL 500 ++ + PR A+ E WS + RL Sbjct: 487 TFSHAQYMVLPRWAALCEVQWSTPDKKNYEDFLSRL 522 >6EZS-A nrPDB Length = 652 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 129/521 (24%), Positives = 224/521 (42%), Gaps = 56/521 (10%) Query: 32 TSDQRYVLYPNNFQFQ-YDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRPYLTGKRHTL 90 T Q + PN+ + + + Q G ++ Y DL + +W L + Sbjct: 137 THAQPLLPKPNHIEVSDHSFTFDEQAGVAI-------YTDLANSAKAW---LLEELQRIH 186 Query: 91 EKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKS- 149 + + + PTL+ Y L ++++ + + + G T QL+ + Sbjct: 187 QFTLSSSNSGKIIFKSNPTLDE-GAYKLKVSEESIKIEAGSSSGFTHACATLLQLLKRDE 245 Query: 150 AEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDP 209 A T I D PRF +RG++LD +RH+ + + ++++A+ KLN FHWHL DD Sbjct: 246 ATKTMEAVCCSIIDSPRFRYRGMMLDCARHFHSVEQVKRLINLLAHYKLNTFHWHLTDDE 305 Query: 210 SFPYESFTFPELMRKGSYNP---------------VTHIYTAQDVKEVIEYARLRGIRVL 254 + E + P+L G++ YT +++++VI +A RGI ++ Sbjct: 306 GWRVEIKSLPQLTEIGAWRGIDETIEPQYTHLSQRYGGFYTQEEIRDVIAFAEQRGITII 365 Query: 255 AEFDTPGHTLSWGPGIPGLLTPCYSGSEPSG----TFGPVNPSLNNTYEFMSTFFLEVSS 310 E D PGH + +P LL +E +NP+L +YEF+ E+++ Sbjct: 366 PEIDVPGHCRAAIKSLPHLLIEAEDTTEYRSIQHYNDNVINPALPGSYEFIDKVLEEIAA 425 Query: 311 VFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGY 370 +FP Y+H+G DEV W +P Q M + G+ D+K+L+ +++ D + GK Sbjct: 426 LFPAPYVHIGADEVPNGVWSKSPACQALMEQLGY-TDYKELQGHFLRHAEDKLRKLGKRM 484 Query: 371 VVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALL--SAPWYLNRISY- 427 + W+E + K+ DT+I W + + GF +L + YL+ Sbjct: 485 LGWEE-AQHGNKVSKDTVIYSWL------SEEAALNCARQGFDVVLQPAQTTYLDMTQDY 537 Query: 428 -----GPDWKDF------YIVEPLA-FEGTPEQKALVIGGEACMWGEYVDNT-NLVPRLW 474 G DW + Y EPLA + + G + +W E ++N + ++ Sbjct: 538 APEEPGVDWANPLPLEKAYNYEPLAEVPADDPIRKRIWGIQTALWCEIINNPSRMDYMIF 597 Query: 475 PRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQ 515 PR A+AE W+ K D T RL L +GV + Sbjct: 598 PRLTAMAEACWTEKQHRDWTDYLSRLKGHLPLLDLQGVNYR 638 >4PYS-A nrPDB Length = 506 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 102/421 (24%), Positives = 183/421 (43%), Gaps = 23/421 (5%) Query: 114 ENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFI-NKTEIEDFPRFPHRGL 172 E Y + + ++ ++ + G + +++ Q W + E I EI DFPR R Sbjct: 78 EGYRIRVTPERIIVEAADDAGFIYAIQSLRQ--WNTGEERGLIFPCVEITDFPRVKWRSF 135 Query: 173 LLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSY----N 228 +LD+ R Y +S+I +D+ + K+N FHWHL + + E +P L R G++ Sbjct: 136 MLDSGRQYQKVSTIKKYIDMASMLKMNYFHWHLTEGLGWRIEIKRYPFLTRIGAFVGQGP 195 Query: 229 PVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTF- 287 Y+ ++VKE+I YA RGI V+ E D PGH + P L + P F Sbjct: 196 EQQGFYSQEEVKEIIGYAADRGITVVPEIDMPGHAEAALNAYPRLGCFNVAVKVPQSGFT 255 Query: 288 -GPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGE 346 ++T F+ EV +FP Y+HLGGDE W P+ + + K+ Sbjct: 256 QNIFCAGKDSTLIFLKNVLDEVCRMFPSAYIHLGGDEAPKGNWDKCPDCRSRIEKEKLK- 314 Query: 347 DFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVW------REDIPVNY 400 D L+ ++ + D + G+ + W +V PD ++ W R+ N Sbjct: 315 DSHDLQLWFSARMADYLKQKGRKAIFWGDVIYKDGYSLPDNVVIQWWNWRGHRDLALKNA 374 Query: 401 MKE-LELVTKAGFRALLS---APWYLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGE 456 ++ ++ + L+ PW + D +D Y+ P E+ L++G Sbjct: 375 VRHNYPVICGTNYYTYLNFPLTPWKGYTQARTFDLEDVYLRNPSY--RPREENPLILGMS 432 Query: 457 ACMWG-EYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQ 515 + +W + V + + R++PR A+AE++W + + Y ++ + ++G Sbjct: 433 SALWTDDGVTESMIDRRVFPRILALAEQMWHSGNPENFDEFYGKVLSKQLWFEQQGYSFG 492 Query: 516 P 516 P Sbjct: 493 P 493 >5OAR-B nrPDB Length = 499 Score = 394 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 143/480 (29%), Positives = 233/480 (48%), Gaps = 85/480 (17%) Query: 113 VENYTLTINDDQ--CLLLSETVWGALRGLETFSQLVWKSAEGTFFINK-TEIEDFPRFPH 169 E+YTL + +D + +ETVWGAL T QLV G I + I+D P +P+ Sbjct: 24 DESYTLDVEEDSDTITINAETVWGALHAFTTLQQLVISDGHGGLIIEEPVNIKDSPLYPY 83 Query: 170 RGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNP 229 RG++LDT R+++ L I + L+ M+ +KLNV HWH+ D S+P +PE+++ +Y+P Sbjct: 84 RGIMLDTGRNFVSLPKIFEQLEGMSLSKLNVLHWHIDDAQSWPIWVDVYPEMVKD-AYSP 142 Query: 230 VTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLS-WGPGIPGLLT-----------PC 277 IY+ DV+ ++ YAR RGIRV+ E D P H+ S W P ++T P Sbjct: 143 HE-IYSRNDVRNIVNYARARGIRVIPEIDMPSHSSSGWKQVDPEMVTCTDSWWSNDDWPL 201 Query: 278 YSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQD 337 ++ EP+ G ++ N TYE + + E+S +FPD + H+GGDE+ C+ + + Sbjct: 202 HTAVEPNP--GQLDIIYNKTYEVVGNVYKELSDIFPDHWFHVGGDEIQPNCFNFSTHV-- 257 Query: 338 FMRKKGFGED----FKQLESFYIQTLLDIVSSYG--KGYVVWQEV---FDNKVKIQPDTI 388 K F ED + L +++ + I +Y + V+W+++ DN + + + Sbjct: 258 ---TKWFAEDPSRTYHDLAQYWVDHAVPIFQNYSQERRLVMWEDIALSADNAHDVPKNIV 314 Query: 389 IQVWREDIPVNYMKELELVTKAGFRALLSAPWYL---------------NRISYGPD--- 430 +Q W N ++ + +T G+ ++S+ +L + PD Sbjct: 315 MQSWN-----NGLEYISNLTARGYDVIVSSSDFLYLDCGHGGFVTNDPRYNVMANPDANT 369 Query: 431 ------------------WKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPR 472 W+ Y + T Q +IG A +WGE VD+ N+ Sbjct: 370 PNFNYGGNGGSWCAPYKTWQRIYDYD-FTLNLTETQAKHIIGATAPLWGEQVDDINVSSM 428 Query: 473 LWPRAGAVAERLWS-------NKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCEQE 525 WPRA A+AE +WS NK T+++T +R+ +FR L+ GVQAQ L +C Q Sbjct: 429 FWPRAAALAELVWSGNRDANGNKRTTEMT---QRILNFREYLVANGVQAQALVPKYCLQH 485 >3SUR-A nrPDB Length = 525 Score = 392 bits (1008), Expect = e-109, Method: Composition-based stats. Identities = 109/432 (25%), Positives = 178/432 (41%), Gaps = 55/432 (12%) Query: 114 ENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEG-------TFFINKTEIEDFPR 166 E Y L +Q L + G RG +T QL+ E + I + I D P Sbjct: 122 EGYDLITTSNQVTLTANKPEGVFRGNQTLLQLLPAGIEKNTVVSGVQWVIPHSNISDKPE 181 Query: 167 FPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGS 226 + +RGL+LD +RH+ + + +D+ + K+N FH HL DD + E ++P+L+ GS Sbjct: 182 YEYRGLMLDVARHFFTVDEVKRQIDLASQYKINKFHMHLSDDQGWRIEIKSWPDLIEIGS 241 Query: 227 Y----NPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGI----PGLLTPCY 278 YT + K+++ YA R I V+ E D PGHT + P Sbjct: 242 KGQVGGGPGGYYTQEQFKDIVSYAAERYIEVIPEIDMPGHTNAALASYGELNPDGKRKAM 301 Query: 279 SGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDF 338 G + + P TY+F+ E++++ P Y+HLGGDE + T Sbjct: 302 RTDTAVG-YSTLMPRAEITYQFVEDVISELAAISPSPYIHLGGDESNATS---------- 350 Query: 339 MRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPV 398 D+ ++ + I +SYGK V W + D D+++Q W Sbjct: 351 ------AADY----DYFFGRVTAIANSYGKKVVGW-DPSDTSSGATSDSVLQNWTCSAST 399 Query: 399 NYMKELELVTKAGFRALLS-APWYLNRISY-----GPDWKDFYIVEPLAFEGTPE---QK 449 G + ++S A YL+ Y G W+ F A+ P + Sbjct: 400 GT-----AAKAKGMKVIVSPANAYLDMKYYSDSPIGLQWRGFVN-TNRAYNWDPTDCIKG 453 Query: 450 ALVIGGEACMWGE-YVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELL 508 A + G E+ +W E +V +L L+P+ + AE W+ + + ERL L Sbjct: 454 ANIYGVESTLWTETFVTQDHLDYMLYPKLLSNAEVGWTARGDRNWDDFKERLIEHTPRLQ 513 Query: 509 RRGVQ--AQPLN 518 +G++ A P+ Sbjct: 514 NKGIKFFADPIV 525 >1HP5-A nrPDB Length = 512 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 108/431 (25%), Positives = 169/431 (39%), Gaps = 57/431 (13%) Query: 113 VENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE------GTFFINKTEIEDFPR 166 E Y L + + G G++T QL+ + E G + + IED PR Sbjct: 97 DEGYRLDSGPAGVTITARKAAGLFHGVQTLRQLLPPAVEKDSAQPGPWLVAGGTIEDTPR 156 Query: 167 FPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGS 226 + R +LD SRH+ + + +D +A K N H HL DD + ++P L G Sbjct: 157 YAWRSAMLDVSRHFFGVDEVKRYIDRVARYKYNKLHLHLSDDQGWRIAIDSWPRLATYGG 216 Query: 227 YNPV----THIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGL-----LTPC 277 V YT + KE++ YA R + V+ E D PGHT + L P Sbjct: 217 STEVGGGPGGYYTKAEYKEIVRYAASRHLEVVPEIDMPGHTNAALASYAELNCDGVAPPL 276 Query: 278 YSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQD 337 Y+G++ F + + TY+F+ E++++ P YLH+GGDE S P+ D Sbjct: 277 YTGTKVG--FSSLCVDKDVTYDFVDDVIGELAALTPGRYLHIGGDEA-----HSTPK-AD 328 Query: 338 FMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIP 397 F+ +++ + IV+ YGK V W ++ + ++Q W D Sbjct: 329 FVA--------------FMKRVQPIVAKYGKTVVGWHQL--AGAEPVEGALVQYWGLDRT 372 Query: 398 VNYMKELELVTKAGFRALLSAPW--------YLNRISYGPDWKDF------YIVEPLAF- 442 + K L+ +P Y G W + Y +P + Sbjct: 373 GDAEKAEVAEAARNGTGLILSPADRTYLDMKYTKDTPLGLSWAGYVEVQRSYDWDPAGYL 432 Query: 443 EGTPEQKALVIGGEACMWGEYVDNTN-LVPRLWPRAGAVAERLWSNKLTSDLTFAYERLS 501 G P V G EA +W E + + + L +PR VAE WS T D RL+ Sbjct: 433 PGAPADA--VRGVEAPLWTETLSDPDQLDYMAFPRLPGVAELGWSPASTHDWDTYKVRLA 490 Query: 502 HFRCELLRRGV 512 G+ Sbjct: 491 AQAPYWEAAGI 501 >4C7D-A nrPDB Length = 494 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 108/433 (24%), Positives = 172/433 (39%), Gaps = 57/433 (13%) Query: 113 VENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE------GTFFINKTEIEDFPR 166 E Y L + + + G G++T QL+ + E G + + IED PR Sbjct: 79 DEGYRLDSGREGVTITARKAAGLFHGVQTLRQLLPAAVEKDSAQPGPWLVAGGTIEDTPR 138 Query: 167 FPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGS 226 + R +LD SRH+ + + +D +A K N H H+ DD + ++P L G Sbjct: 139 YAWRSAMLDVSRHFFSVDEVKRYIDRVALYKYNKLHLHISDDQGWRLAIDSWPRLATYGG 198 Query: 227 YNPVTHI----YTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGL-----LTPC 277 V YT D +E++ YA R + V+ E D PGHT + L P Sbjct: 199 STEVGGGPGGHYTKADYEEIVRYAASRHLEVVPEIDMPGHTNAALASYAELNCDGVAPPL 258 Query: 278 YSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQD 337 Y+G++ F + + TY+F+ E++++ P YLH+GGDE S P+ D Sbjct: 259 YTGTKVG--FSTLCVDKDVTYDFVDDVLGELAALTPGRYLHIGGDEA-----HSTPQ-AD 310 Query: 338 FMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIP 397 F+ +++ + IV+ YGK V W ++ + ++Q W D Sbjct: 311 FVA--------------FMKRVQPIVAKYGKTVVGWHQL--AGAEPVEGALVQYWGLDRT 354 Query: 398 VNYMKELELVTKAGFRALLSAPW--------YLNRISYGPDWKDF------YIVEPLAF- 442 + K L+ +P Y G W + Y +P A+ Sbjct: 355 SDAEKAQVAAAARNGTGLILSPADRTYLDMKYTKDTPLGLSWAGYVEVRRSYDWDPAAYL 414 Query: 443 EGTPEQKALVIGGEACMWGEYVDNTN-LVPRLWPRAGAVAERLWSNKLTSDLTFAYERLS 501 G P + V G EA +W E + + + L +PR VAE WS T D RL+ Sbjct: 415 PGAPAEA--VRGVEAPLWTETLSDPDQLDFMAFPRLPGVAELGWSPASTHDWDTYKVRLA 472 Query: 502 HFRCELLRRGVQA 514 G+ Sbjct: 473 GQAPHWEAMGIDY 485 >3RCN-A nrPDB Length = 543 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 121/456 (26%), Positives = 202/456 (44%), Gaps = 56/456 (12%) Query: 108 PTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLV--------WKSAEGTFFINKT 159 P+L++ E Y L ++D ++ + GA G +T QL+ A + + + Sbjct: 73 PSLDA-EAYRLEVSDA-VVISAGGAAGAFYGAQTLLQLLGPAALRQAPVVAVEGWSVPRV 130 Query: 160 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 219 +ED PRF +RG +LD +RH++P ++L ++VMA +KLNV H HL DD + + +P Sbjct: 131 SVEDKPRFGYRGTMLDVARHFMPKDNVLRFIEVMAMHKLNVLHLHLTDDQGWRMQINRYP 190 Query: 220 ELMRKGSY----------------NPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHT 263 +L G++ P YT D++E++ +A R I V+ E D PGH+ Sbjct: 191 KLTETGAWRRESSLGSWRAGVFDGRPHGGFYTQDDLREIVAFAADRHITVIPEIDVPGHS 250 Query: 264 LSWGPGIPGLLTPCYSGSEP------SGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYL 317 + P L GS P G V + EF EV +FP ++ Sbjct: 251 QAAIAAYPELGAGPADGSSPVEVWTRWGINETVLEVSETSLEFYRNVLDEVVEIFPSPWI 310 Query: 318 HLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVF 377 LGGDEV T W+++ + Q + G +D L S+++ L + +G+ VW E+ Sbjct: 311 SLGGDEVPLTQWQASAQAQAKAAELGL-DDVSGLHSWFVGQLALHLKHHGRATSVWDEIG 369 Query: 378 DNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLN---RISYGPD---- 430 D + ++ WR Y ++ + K G+ ++ L R + G D Sbjct: 370 DGG--LPDGALVASWR-----GYEGGIDALRK-GYDVVMCPEHKLYLDHRQADGDDEPVP 421 Query: 431 ------WKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPR-LWPRAGAVAER 483 + Y EPL + ++G +A +W E++D+ V +PR A++E Sbjct: 422 VGFVTTLQAVYEFEPLPGVEGTDFPGRLLGAQANIWSEHLDSPRRVQFAAFPRLSAISEV 481 Query: 484 LWSNKLTSDLTFAYERLSHFRCELLR-RGVQAQPLN 518 WSN D RL+ L GV+ +PL+ Sbjct: 482 FWSNPAGRDYDEFLTRLTGAHLARLEAMGVEYRPLS 517 >2GK1-N nrPDB Length = 237 Score = 319 bits (816), Expect = 2e-87, Method: Composition-based stats. Identities = 147/239 (61%), Positives = 187/239 (78%), Gaps = 3/239 (1%) Query: 285 GTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGF 344 +FGP+NP+LN TY F++TFF E+S VFPD ++HLGGDEV+F CW+SNP+IQDFMR+KGF Sbjct: 2 DSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGF 61 Query: 345 GEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKEL 404 G DFK+LESFYIQ +LDI+++ KG +VWQEVFD+K K+ P TI++VW++ Y +EL Sbjct: 62 GTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSA---YPEEL 118 Query: 405 ELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYV 464 VT +GF +LSAPWYL+ ISYG DW+ +Y VEPL F GT +QK L IGGEAC+WGEYV Sbjct: 119 SRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTQKQKQLFIGGEACLWGEYV 178 Query: 465 DNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCE 523 D TNL PRLWPRA AV ERLWS+K D+ AY+RL+ RC ++ RG+ AQPL G+C Sbjct: 179 DATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLTRHRCRMVERGIAAQPLYAGYCN 237 >1QBA-A nrPDB Length = 858 Score = 287 bits (734), Expect = 7e-78, Method: Composition-based stats. Identities = 120/597 (20%), Positives = 201/597 (33%), Gaps = 140/597 (23%) Query: 11 LLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRD 70 L A A G+ P P + Q L D+S+ +P V+ QR+ Sbjct: 181 LPAGALRGKIV---PTPMQVKVHAQDADLRKG---VALDLSTLVKPAADVVS---QRFAL 231 Query: 71 LLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSE 130 L + P T + K + VS Y L I + ++ Sbjct: 232 LGVPVQTNGYPIKTDIQPGKFKGAMAVS---------------GAYELKIGKKEAQVIGF 276 Query: 131 TVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTL 190 G GL++ LV ++G+ I + D PRFP+RG+ LD +R++ ++L L Sbjct: 277 DQAGVFYGLQSILSLVP--SDGSGKIATLDASDAPRFPYRGIFLDVARNFHKKDAVLRLL 334 Query: 191 DVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPV-------------------T 231 D MA KLN FH+HL DD + E PEL G Sbjct: 335 DQMAAYKLNKFHFHLSDDEGWRIEIPGLPELTEVGGQRCHDLSETTCLLPQYGQGPDVYG 394 Query: 232 HIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIP------------------GL 273 ++ QD ++I+YA+ R I V+ E D P H + + L Sbjct: 395 GFFSRQDYIDIIKYAQARQIEVIPEIDMPAHARAAVVSMEARYKKLHAAGKEQEANEFRL 454 Query: 274 LTPCYSGSEPSGTF----GPVNPSLNNTYEFMSTFFLEVSSVF-----PDFYLHLGGDEV 324 + P + + S F +NP L+++ F+ E++ + P H GGDE Sbjct: 455 VDPTDTSNTTSVQFFNRQSYLNPCLDSSQRFVDKVIGEIAQMHKEAGQPIKTWHFGGDEA 514 Query: 325 DFTC--------------------------WKSNPEIQDFMRKKGFGEDFKQLESFYIQT 358 W + ++ M K+G D + L S++ Q Sbjct: 515 KNIRLGAGYTDKAKPEPGKGIIDQGNEDKPWAKS-QVCQTMIKEGKVADMEHLPSYFGQE 573 Query: 359 LLDIVSSYGK-GYVVWQEVFDNKVKIQPDTI----IQVWREDIPVNYMKELELVTKAGFR 413 + +V ++G WQ+ + + + W + + + G+ Sbjct: 574 VSKLVKAHGIDRMQAWQDGLKDAESSKAFATSRVGVNFW-DTLYWGGFDSVNDWANKGYE 632 Query: 414 ALLSAPWYLNR---ISYGPDWKDFY---------------------------IVEPLAFE 443 ++S P Y+ PD + +Y + F Sbjct: 633 VVVSNPDYVYMDFPYEVNPDERGYYWGTRFSDERKVFSFAPDNMPQNAETSVDRDGNHFN 692 Query: 444 GTPEQK-ALVIGGEACMWGE-YVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYE 498 ++ G A +W E + + ++PRA +VAER W Y Sbjct: 693 AKSDKPWPGAYGLSAQLWSETQRTDPQMEYMIFPRALSVAERSWHRAG---WEQDYR 746 >5BXR-A nrPDB Length = 644 Score = 273 bits (698), Expect = 1e-73, Method: Composition-based stats. Identities = 80/393 (20%), Positives = 146/393 (37%), Gaps = 39/393 (9%) Query: 113 VENYTLTINDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGL 172 E + L I ++ T G G + SQ++ +G + + P++ RG Sbjct: 109 DEGFKLNIGSKGLEVIGATDIGVFYGTRSVSQML---RQGQLTLPAGTVATKPKYKERGA 165 Query: 173 LLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTH 232 L + + I L MA +LN + L++ P E T +K + Sbjct: 166 TLCACQINISTDWIDRFLSDMADLRLN---YVLLEMKLKPEEDNT-----KKAA---TWS 214 Query: 233 IYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNP 292 YT DVK+ ++ A GI V+ E ++PGH W P SG + NP Sbjct: 215 YYTRDDVKKFVKKANNYGIDVIPEINSPGHMNVWLENYPEYQLADNSGRKDPNKLDISNP 274 Query: 293 SLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDF-TCWKSNPEIQDFMRKK-GFGEDFKQ 350 +F T E VF Y H+G DE T + + +++ F K+ G G Sbjct: 275 ---EAVKFYKTLIDEYDGVFTTKYWHMGADEYMIGTSFDNYSKLKTFAEKQYGAGATPND 331 Query: 351 LESFYIQTLLDIVSSYGKGYVVWQE--VFDNKVKIQPDTIIQVWREDIPVNYMKELELVT 408 + +I + V + GK +W + V V + D +I+ W ++ + + Sbjct: 332 AFTGFINDIDKYVKAKGKQLRIWNDGIVNTKNVSLNKDIVIEYW-----YGAGRKPQELV 386 Query: 409 KAGFRALLSAPWYLNR----ISYGPDWKDFYIV--EPLAFEGTPEQKAL---VIGGEACM 459 + G+ L++A L Y + Y F+G + + G + + Sbjct: 387 QDGYT-LMNATQALYWSRSAQVYKVNAARLYNNNWNVGTFDGGRQIDKNYDKLTGAKVSI 445 Query: 460 WGE---YVDNTNLVPRLWPRAGAVAERLWSNKL 489 W + + + ++ +++ WS+ Sbjct: 446 WPDSSYFQTENEVEKEIFDGMRFISQMTWSDSR 478 >1NP0-C nrPDB Length = 190 Score = 255 bits (651), Expect = 3e-68, Method: Composition-based stats. Identities = 117/191 (61%), Positives = 143/191 (74%), Gaps = 1/191 (0%) Query: 89 TLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLETFSQLVWK 148 T + +LV + C+ P + S E+YTL + + +L + VWGALRGLETFSQLV++ Sbjct: 1 TQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQ 60 Query: 149 SAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD 208 + GTF IN++ I D PRF HRG+L+DTSRHYLP+ IL TLD MA+NK NV HWH+VDD Sbjct: 61 DSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDD 120 Query: 209 PSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP 268 SFPY+S TFPEL KGSY+ ++H+YT DV+ VIEYARLRGIRVL EFDTPGHTLSWG Sbjct: 121 QSFPYQSITFPELSNKGSYS-LSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGK 179 Query: 269 GIPGLLTPCYS 279 G LLTPCYS Sbjct: 180 GQKDLLTPCYS 190 >1YHT-A nrPDB Length = 367 Score = 180 bits (457), Expect = 1e-45, Method: Composition-based stats. Identities = 64/331 (19%), Positives = 113/331 (34%), Gaps = 57/331 (17%) Query: 171 GLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELM------RK 224 GL+LD +RH+ I +D ++ + N H H D ++ ES + + Sbjct: 20 GLMLDIARHFYSPEVIKSFIDTISLSGGNFLHLHFSDHENYAIESHLLNQRAENAVQGKD 79 Query: 225 GSY-NPVTH--IYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCY-SG 280 G Y NP T + + + ++ YA+ +GI ++ E D+P H + + Y G Sbjct: 80 GIYINPYTGKPFLSYRQLDDIKAYAKAKGIELIPELDSPNHMTAIFKLVQKDRGVKYLQG 139 Query: 281 SEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVF--PDFYLHLGGDEVDFTCWKSNPEIQDF 338 + ++ + ++ FM + EV +F + H+GGDE Sbjct: 140 LKSRQVDDEIDITNADSITFMQSLMSEVIDIFGDTSQHFHIGGDEF-------------- 185 Query: 339 MRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQE--VFDNKVKIQPDTIIQVWREDI 396 G+ + Y L + G +W + + + +I P+ I W D Sbjct: 186 ----GYSVESNHEFITYANKLSYFLEKKGLKTRMWNDGLIKNTFEQINPNIEITYWSYDG 241 Query: 397 PVNYMKE----------LELVTKAGFRALLSAPWYLNRIS---------YGPDWKDFYIV 437 E L + GF L +YL + KD Sbjct: 242 DTQDKNEAAERRDMRVSLPELLAKGFTVLNYNSYYLYIVPKASPTFSQDAAFAAKDVIKN 301 Query: 438 EPLAF-EGTPEQKA-----LVIGGEACMWGE 462 L +G + + G +WGE Sbjct: 302 WDLGVWDGRNTKNRVQNTHEIAGAALSIWGE 332 >5MI4-A nrPDB Length = 727 Score = 138 bits (347), Expect = 6e-33, Method: Composition-based stats. Identities = 42/181 (23%), Positives = 78/181 (43%), Gaps = 29/181 (16%) Query: 80 RPYLTGKRHTLEKNVLVVSVVTPG-------CNQLPTLESVENYTLTINDDQCLLLSETV 132 + L+GK+ + K +++S+ G Q+P + E Y L++N+ + +L Sbjct: 53 KELLSGKQSS--KKGMLISIGEKGDKSVRKYSRQIP--DHKEGYYLSVNEKEIVLAGNDE 108 Query: 133 WGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDV 192 G L+TF+QL+ + + EI+D+P +RG++ + L L Sbjct: 109 RGTYYALQTFAQLLKDGK-----LPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKF 163 Query: 193 MAYNKLNVFHWHLVDD-----PSFPY-----ESFTFPELMRKGSYNP---VTHIYTAQDV 239 NK+N + + DD P++ E+ EL+ + N V I+ QD+ Sbjct: 164 YGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDI 223 Query: 240 K 240 K Sbjct: 224 K 224 >2YLL-A nrPDB Length = 454 Score = 102 bits (254), Expect = 4e-22, Method: Composition-based stats. Identities = 53/343 (15%), Positives = 110/343 (32%), Gaps = 45/343 (13%) Query: 174 LDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD-------------PSFPYESFTFPE 220 +D R Y + + +D + H + +D Y S Sbjct: 32 IDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKR 91 Query: 221 LMRKGS---YN-PVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLT- 275 + KG+ YN P + T + ++I YA+ +GI ++ ++PGH + + L Sbjct: 92 AIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQ 151 Query: 276 ---PCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFP--DFYLHLGGDEVDFTCWK 330 Y G + + V+ F + ++ F ++G DE Sbjct: 152 NPNFSYFGKKSAR---TVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATD 208 Query: 331 SNP----EIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQ-- 384 + + + +G+ + Y L IV S+G + + + Sbjct: 209 AKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFG 268 Query: 385 ---PDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEP-- 439 D I+ +W + +L+ + G + L + + + D + +Y ++ Sbjct: 269 SFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGL 328 Query: 440 --------LAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLW 474 + T +IGG W + RL+ Sbjct: 329 NGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSRLF 371 >2YL9-A nrPDB Length = 457 Score = 84.5 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 56/372 (15%), Positives = 112/372 (30%), Gaps = 48/372 (12%) Query: 172 LLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD-------------PSFPYESFTF 218 + +D R Y L+ + +D + + H L +D Y S Sbjct: 30 ISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDV 89 Query: 219 PELMRKGSY----NPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLL 274 + + +G+ +P T +V E+IEYA+ + I ++ ++PGH + + L Sbjct: 90 KKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLG 149 Query: 275 TPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFP--DFYLHLGGDEVDFTCWKSN 332 + ++ F+ + F + G D+ Sbjct: 150 IKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDQYA----NDA 205 Query: 333 PEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFD----NKVKIQPDTI 388 Q + K + + Y TL + G + + + F + V+ D + Sbjct: 206 TSAQGWYYLKWYQ--LYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVL 263 Query: 389 IQVWREDIPVNYMKELELVTKAGFRAL-LSAPWYLNRISYGPDWKDFYI----------V 437 I W + + + + G++ L + WY D F Sbjct: 264 ISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPF 323 Query: 438 EPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAY 497 LA PE +G +W + ++ A A + + Sbjct: 324 NQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA--------DHNKDYFR 375 Query: 498 ERLSHFRCELLR 509 + R EL + Sbjct: 376 ANYNALREELAK 387 >2EPK-X nrPDB Length = 627 Score = 61.3 bits (147), Expect = 9e-10, Method: Composition-based stats. Identities = 41/222 (18%), Positives = 83/222 (37%), Gaps = 27/222 (12%) Query: 158 KTEIEDFPRFPHRGLLLDTSRH-YLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESF 216 + +IE+ + + D SR+ L LSS ++V+A + F ++ D YE Sbjct: 75 EVQIEEEAAYEDLAYMADCSRNAVLNLSSAKKMIEVLALMGYSTFELYMEDT----YEIE 130 Query: 217 TFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP-GIPGLLT 275 P + YT +++E+ +YA + + T H ++ GI + Sbjct: 131 NQPY------FGYFRGRYTVAELQEIEDYAADFDMSFVPCIQTLAHLSAFVKWGIKEVQ- 183 Query: 276 PCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEI 335 E + Y+ + F ++ + +++G DE + Sbjct: 184 ------ELRDVEDILLIGEEKVYDLIEGMFQTMAHLHTRK-INIGMDEAHLV------GL 230 Query: 336 QDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVF 377 ++ K GF + ++ +LDI YG +W ++F Sbjct: 231 GRYLIKHGFQNRSLLMCQH-LERVLDIADKYGFNCQMWSDMF 271 >5A6B-D nrPDB Length = 648 Score = 59.8 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 37/222 (16%), Positives = 85/222 (38%), Gaps = 27/222 (12%) Query: 158 KTEIEDFPRFPHRGLLLDTSRH-YLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESF 216 K EIE+ + ++D SR+ L ++S ++++A + F ++ D Y+ Sbjct: 97 KVEIEEQAAYEDLAYMVDCSRNAVLNVASAKQMIEILALMGYSTFELYMEDT----YQIE 152 Query: 217 TFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGP-GIPGLLT 275 P + Y+A++++E+ YA+ + + T H ++ G+ + Sbjct: 153 GQPY------FGYFRGAYSAEELQEIEAYAQQFDVTFVPCIQTLAHLSAFVKWGVKEVQ- 205 Query: 276 PCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEI 335 E + Y+ + F +S + +++G DE + Sbjct: 206 ------ELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRK-VNIGMDEAHLV------GL 252 Query: 336 QDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVF 377 ++ G + + ++ +LDI YG +W ++F Sbjct: 253 GRYLILNGVVDRSLLMCQH-LERVLDIADKYGFHCQMWSDMF 293 >3EMC-A nrPDB Length = 331 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 6/73 (8%) Query: 213 YESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPG 272 Y S T M+ +P H YT + E++++A RGI V GHTL W P Sbjct: 37 YNSVTAENQMKFEEVHPREHEYTFEAADEIVDFAVARGIGV------RGHTLVWHNQTPA 90 Query: 273 LLTPCYSGSEPSG 285 + SG S Sbjct: 91 WMFEDASGGTASR 103 >6FHE-A nrPDB Length = 339 Score = 35.5 bits (80), Expect = 0.057, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 27/74 (36%), Gaps = 6/74 (8%) Query: 222 MRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGS 281 M+ S P Y +D ++ +A G++ GHTL W +P +G+ Sbjct: 55 MKPESLEPEEGRYNFEDADRIVAFAEKHGMK------MRGHTLVWHQQVPDWFFLDENGN 108 Query: 282 EPSGTFGPVNPSLN 295 P N N Sbjct: 109 PMVDETDPKNREAN 122 >1L8N-A nrPDB Length = 679 Score = 34.0 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 11/85 (12%) Query: 93 NVLVVSVVTPGCNQLP---TLESVENYTLTI----NDDQCLLLSETVWGALRGLETFSQL 145 N + + + + P TL E Y + + ++ +T G L G+ F +L Sbjct: 65 NSIWLGTLEDEEFERPLEGTLVHPEGYVIRSDVDDGPFRIYIIGKTDAGVLYGVFHFLRL 124 Query: 146 VWKSAEGTFFINKTEIEDFPRFPHR 170 + + I + I + P+ R Sbjct: 125 L----QMGENIAQLSIIEQPKNRLR 145 >2D73-A nrPDB Length = 738 Score = 33.6 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 37/113 (32%), Gaps = 10/113 (8%) Query: 177 SRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTA 236 +H +++ +D A + + + + + ++ VT Y Sbjct: 364 GKHSANTANVKRYIDFAAAHGFDAVLV-----EGWNEGWEDWFGNSKDYVFDFVTP-YPD 417 Query: 237 QDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGP 289 DVKE+ YA +GI+++ T + + Y +G Sbjct: 418 FDVKEIHRYAARKGIKMM----MHHETSASVRNYERHMDKAYQFMADNGYNSV 466 >1LQS-L nrPDB Length = 157 Score = 33.2 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 5/95 (5%) Query: 57 GCSVLDEAFQRYRDLLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENY 116 GCSV+D +RY +++F +G P L + H++ + + Q P L + Sbjct: 62 GCSVMDWLLRRYLEIVFPAGDHVYPGLKTELHSMRSTLESIY---KDMRQCPLLGCGDKS 118 Query: 117 TLTINDDQCLLLSETVWGALRGLETFSQLVWKSAE 151 ++ + S G +GL L + E Sbjct: 119 VISRLSQEAERKS--DNGTRKGLSELDTLFSRLEE 151 >4DIK-A nrPDB Length = 410 Score = 32.8 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 18/52 (34%) Query: 259 TPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSS 310 PGH L W LL S ++ G V ++ Y F+ + Sbjct: 237 LPGHGLIWKKDPQRLLNHYVSVAKGDPKKGKVTVIYDSMYGFVENVMKKAID 288 >5M7S-A nrPDB Length = 916 Score = 32.4 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 12/91 (13%), Positives = 28/91 (30%), Gaps = 13/91 (14%) Query: 171 GLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPV 230 G++ + + + +LN + + DD + + Sbjct: 63 GVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRM------------FWREM 110 Query: 231 THIYTAQDVKEVIEYARLRGIRVLAEFDTPG 261 + A+ + +I AR I + +PG Sbjct: 111 YSVEEAEQLMTLISAAREYEIEFIYAI-SPG 140 >3W26-A nrPDB Length = 336 Score = 32.1 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 36/113 (31%), Gaps = 25/113 (22%) Query: 222 MRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGS 281 M+ S P +T + ++++YA ++ GHTL W +P Sbjct: 51 MKPESLQPTEGNFTFDNADKIVDYAIAHNMK------MRGHTLLWHNQVPD--------- 95 Query: 282 EPSGTFGPVNPSLNNT----YEFMSTFFLEVSSVFPDFYLHLGGDEVDFTCWK 330 P +PS + + + T V F Y G + W Sbjct: 96 --WFFQDPSDPSKPASRDLLLQRLRTHITTVLDHFKTKY----GSQNPIIGWD 142 >2XSA-A nrPDB Length = 447 Score = 32.1 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 19/59 (32%), Gaps = 6/59 (10%) Query: 171 GLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDD----PSF--PYESFTFPELMR 223 G++ +D +A +N + + DD + PY++ L Sbjct: 4 GVIEGFYGRDWRRDERATVMDWIAAAGMNTYIYGPKDDVHVRARWRVPYDAAGLARLTE 62 >5OT1-A nrPDB Length = 765 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 4/58 (6%) Query: 227 YNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPS 284 Y T +++E ++ A RG+RV+ +F P H G G P L G+E Sbjct: 389 YRLDPKFGTEDELREFLDEAHRRGMRVIFDF-VPNHC---GIGNPAFLDVWEKGNESP 442 >4ML9-A nrPDB Length = 286 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 43/119 (36%), Gaps = 10/119 (8%) Query: 178 RHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPS-----FPYESFT--FPELMRKGSYNPV 230 RH +PL +L + N + + V P P E F ++ G+ Sbjct: 82 RHEIPLDEMLKVTQGV-RNVVGEDIYITVGVPGGFTEILPLELKEEDFFKIAMSGADGVH 140 Query: 231 THIYTAQDVKEVIEYARLRGIRVLAEFDTPG--HTLSWGPGIPGLLTPCYSGSEPSGTF 287 H T +D+K+V++YA G+ V A P HT P + E G Sbjct: 141 IHKSTLEDLKDVVKYAHKYGLLVDAYIGHPDDLHTFGISARTPEEVAEAAKEMEKIGVD 199 >5GNE-A nrPDB Length = 375 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 22/64 (34%) Query: 325 DFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQ 384 W++N + ++ + + ++ Q + YG+ V V IQ Sbjct: 111 PAKIWQTNQHLTSYINRSAKSRTGVEAAQWFKQQFDTLAQDYGRKDVESYFVKTGNKFIQ 170 Query: 385 PDTI 388 P + Sbjct: 171 PSVV 174 >1WZ2-A nrPDB Length = 967 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 39/116 (33%), Gaps = 17/116 (14%) Query: 147 WKSAEGTFFINKTEIEDFPR---------FPHRG--LLLDTSRHYLPLSSILDTLDVMAY 195 W+ I + I D P+ FP+ L + +R Y I + Y Sbjct: 13 WQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGY 72 Query: 196 NKLNVFHWHLVDDP--SFPYESFTF-PE---LMRKGSYNPVTHIYTAQDVKEVIEY 245 N L WH+ P P+ + R P ++T +D +++Y Sbjct: 73 NVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEILWTFEDPINIVKY 128 >2A1L-A nrPDB Length = 270 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 38/112 (33%), Gaps = 15/112 (13%) Query: 329 WKSNPEIQDFMRKKGFGED-FKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDT 387 W + P + + + +D F ++E+++ L + + +G W+ V + I + Sbjct: 87 WNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNTWKTVEIVHIDIADRS 146 Query: 388 IIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEP 439 ++ KA L R GP+WK P Sbjct: 147 QVE--------------PADYKADEDPALFQSVKTKRGPLGPNWKKELANTP 184 >1WKB-A nrPDB Length = 810 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 39/116 (33%), Gaps = 17/116 (14%) Query: 147 WKSAEGTFFINKTEIEDFPR---------FPHRG--LLLDTSRHYLPLSSILDTLDVMAY 195 W+ I + I D P+ FP+ L + +R Y I + Y Sbjct: 13 WQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGY 72 Query: 196 NKLNVFHWHLVDDP--SFPYESFTF-PE---LMRKGSYNPVTHIYTAQDVKEVIEY 245 N L WH+ P P+ + R P ++T +D +++Y Sbjct: 73 NVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEILWTFEDPINIVKY 128 >1TJ7-A nrPDB Length = 457 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 33/104 (31%), Gaps = 12/104 (11%) Query: 341 KKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVW----QEVFDNKVKIQPDTIIQVWREDI 396 ++ D + + S+ L+D V GK +V + DT+ ++ Sbjct: 74 QQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSEL--LTA 131 Query: 397 PVNYMKELELVTKAGFRALLSAPWYLNRISYGP----DWKDFYI 436 L + A++ P Y + P W Y+ Sbjct: 132 NRQLQSALVETAQNNQDAVM--PGYTHLQRAQPVTFAHWCLAYV 173 >3QQQ-A nrPDB Length = 168 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 20/47 (42%), Gaps = 1/47 (2%) Query: 241 EVIEYARLRGI-RVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGT 286 EV +A L I + E +P +WG L+ S +PS T Sbjct: 122 EVTRFALLETIKEAVPEMWSPEMKNAWGEAYDQLVAAIKSEMKPSST 168 >4W8I-A nrPDB Length = 551 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 28/78 (35%), Gaps = 4/78 (5%) Query: 224 KGSYNPVTHIYTAQDVKEVIEY---ARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSG 280 K Y +TH T ++ + Y AR +GI E P + L Sbjct: 156 KEGYGLLTHGGTTSIIEAMAAYVIRARAKGID-YPEIVVPETAHAAFKKAAELTGAILIT 214 Query: 281 SEPSGTFGPVNPSLNNTY 298 G VNP++ ++Y Sbjct: 215 VPVDKKTGAVNPNVMSSY 232 >1YKN-B nrPDB Length = 238 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 34/106 (32%), Gaps = 13/106 (12%) Query: 342 KGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYM 401 GFG L + L I G+ +V V D K P+T++++W+ + Sbjct: 54 LGFGAHDHDLLLNFNNGGLPI----GERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRER 109 Query: 402 KELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIV---EPLAFEG 444 + + P + D +Y +P + Sbjct: 110 HKNDRYLAP------LDPNFGGVGRCLTDSDGYYSFRTIKPGPYPW 149 >5H2T-A nrPDB Length = 601 Score = 29.8 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 53/155 (34%), Gaps = 14/155 (9%) Query: 196 NKLNVFHWHLVDDPSFPYESFTFPELMRKGSY--NPVTHIYTA----QDVKEVIEYARLR 249 N+L+ W L D + + P +R G Y + T I D E+++ A R Sbjct: 52 NRLDYLQW-LGIDCIWLLPIYQSP--LRDGGYDISDYTKILPEFGDLGDFVELVDEAHRR 108 Query: 250 GIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNT-YEFMSTFFLE- 307 GIRV+A+ HT P T + + + F+ T Sbjct: 109 GIRVIADLVM-NHTSDQHPWFQASRTDPDGPYGDFYMWSDTDDKYPDARIIFVDTEVSNW 167 Query: 308 -VSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 341 V +Y H + NP +Q+ M + Sbjct: 168 TYDPVRGQYYWHRFFSHQPDLNYD-NPAVQEAMLE 201 >1SVV-A nrPDB Length = 359 Score = 29.0 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 35/95 (36%), Gaps = 7/95 (7%) Query: 212 PYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGI-------RVLAEFDTPGHTL 264 E P+L+ + V YT Q+++++ + G+ R+ + +P + L Sbjct: 139 RSEHMVIPKLVYISNTTEVGTQYTKQELEDISASCKEHGLYLFLDGARLASALSSPVNDL 198 Query: 265 SWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYE 299 + ++ G FG LN+ + Sbjct: 199 TLADIARLTDMFYIGATKAGGMFGEALIILNDALK 233 >5C70-A nrPDB Length = 612 Score = 29.0 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 11/97 (11%) Query: 213 YESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWGPGIPG 272 Y F L G+ + T Y + EV+EYA +GI V+ E G S G G Sbjct: 320 YMVHDFQLLHWMGANSFRTSHYPYAE--EVMEYADRQGIVVIDETPAVGLAFSIGAGAQ- 376 Query: 273 LLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVS 309 S P TF P + N T E + E+ Sbjct: 377 -------TSNPPATFSP-DRINNKTREAHAQAIRELI 405 >1B5E-A nrPDB Length = 246 Score = 28.6 bits (62), Expect = 7.5, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 26/59 (44%), Gaps = 1/59 (1%) Query: 343 GFGEDFKQLESFYIQTLLDIVSSY-GKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNY 400 +++ Q E + ++ V G+ +WQ+V +K +I + +W ED Y Sbjct: 51 ALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAIWSEDNYAQY 109 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.124 0.336 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,824,860 Number of Sequences: 36641 Number of extensions: 781461 Number of successful extensions: 2405 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 53 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 2208 Number of HSP's gapped (non-prelim): 87 length of query: 529 length of database: 10,336,785 effective HSP length: 102 effective length of query: 427 effective length of database: 6,599,403 effective search space: 2817945081 effective search space used: 2817945081 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)