BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P06802 (906 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4B56-A nrPDB 1709 0.0 6C01-A nrPDB 914 0.0 6G4G-A nrPDB 862 0.0 5GZ5-A nrPDB 848 0.0 5OLB-A nrPDB 732 0.0 5MHP-A nrPDB 731 0.0 4LR2-A nrPDB 244 8e-65 5VEN-A nrPDB 233 2e-61 5VEM-A nrPDB 228 7e-60 5EGE-A nrPDB 191 1e-48 5UDY-A nrPDB 184 2e-46 1EI6-A nrPDB 53 5e-07 3T02-A nrPDB 50 5e-06 3LGD-A nrPDB 35 0.15 5TOO-A nrPDB 35 0.21 5XWI-A nrPDB 34 0.22 1E2S-P nrPDB 33 0.66 5MI4-A nrPDB 30 4.3 >4B56-A nrPDB Length = 820 Score = 1709 bits (4425), Expect = 0.0, Method: Compositional matrix adjust. Identities = 820/820 (100%), Positives = 820/820 (100%) Query: 87 VKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVC 146 VKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVC Sbjct: 1 VKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVC 60 Query: 147 SCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEY 206 SCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEY Sbjct: 61 SCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEY 120 Query: 207 LHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKM 266 LHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKM Sbjct: 121 LHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKM 180 Query: 267 NASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSV 326 NASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSV Sbjct: 181 NASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSV 240 Query: 327 PFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLM 386 PFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLM Sbjct: 241 PFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLM 300 Query: 387 DGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPE 446 DGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPE Sbjct: 301 DGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPE 360 Query: 447 TYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNP 506 TYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNP Sbjct: 361 TYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNP 420 Query: 507 SERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPN 566 SERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPN Sbjct: 421 SERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPN 480 Query: 567 NGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPWIVPIKDFEKQLNLT 626 NGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPWIVPIKDFEKQLNLT Sbjct: 481 NGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPWIVPIKDFEKQLNLT 540 Query: 627 TEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLRNDQFSR 686 TEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLRNDQFSR Sbjct: 541 TEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLRNDQFSR 600 Query: 687 DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALLTSNIVPM 746 DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALLTSNIVPM Sbjct: 601 DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALLTSNIVPM 660 Query: 747 YQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEI 806 YQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEI Sbjct: 661 YQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEI 720 Query: 807 LIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLH 866 LIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLH Sbjct: 721 LIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLH 780 Query: 867 RARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED 906 RARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED Sbjct: 781 RARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED 820 >6C01-A nrPDB Length = 838 Score = 914 bits (2361), Expect = 0.0, Method: Compositional matrix adjust. Identities = 434/824 (52%), Positives = 577/824 (70%), Gaps = 15/824 (1%) Query: 89 SCKGRCFERTF---SNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFV 145 SC+ +CF+ +F NCRCD AC G+CC DF++TCVE T IW CNKFRCGE RL + Sbjct: 16 SCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASL 75 Query: 146 CSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAE 205 CSC+DDC DCC +Y SVCQ + SW+EE C++ +CP F+ PP +LFS+DGFRAE Sbjct: 76 CSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAE 135 Query: 206 YLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 265 YL+TW L+P I+KLK CG ++K MR MYPTKTFPNHY+IVTGLYPESHGIIDN MYD Sbjct: 136 YLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVN 195 Query: 266 MNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGS 325 +N +FSL SKE+ NP W+ GQP+W+TA +Q +K+ TYFWPGS+V I+G P IY YNGS Sbjct: 196 LNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGS 255 Query: 326 VPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGML 385 VPFEERI +L+WL LP ERP FYT+Y EEPDSSGH+ GPVS+ VIKALQ VD GML Sbjct: 256 VPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGML 315 Query: 386 MDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVP 445 M+GLK L C+N+IL++DHGM+Q C K Y+ Y +N + GPA R+R ++P Sbjct: 316 MEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIP 375 Query: 446 ETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALN 505 ++SFN E + +NLSCR+P+QHF+PYL P LPKRLH+AK+ RI+ + ++D QW LA+ Sbjct: 376 HDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW-LAVR 434 Query: 506 PSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAP 565 CG G HG +N F +M+A+F+ +GP+FK EV+ FENIEVYNLMCDLL + PAP Sbjct: 435 SKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAP 494 Query: 566 NNGSHGSLNHLLKKPIYNPSHPKEEGFLSQC----PIKSTSNDLGCTCDPWIVPIKDFEK 621 NNG+HGSLNHLLK P Y PSH +E S C P+ + S D C ++ + Sbjct: 495 NNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQ 554 Query: 622 QLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTF--L 679 LNLT E++ + +P+GRPR+L K CLL +++++G+ + MP+W+SYT L Sbjct: 555 MLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQL 614 Query: 680 RNDQFSRDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALL 739 + +CL D+R+P S KCS+Y ++ +++GFL PP NR S+ Y +AL+ Sbjct: 615 GDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQY-DALI 673 Query: 740 TSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSR 799 TSN+VPMY+ F+ +W Y H LL ++A ERNG+NVVSGP+FD++YDG +D+ + + ++ Sbjct: 674 TSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKH-- 731 Query: 800 VIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTHGKRESSW 858 + + ++ IPTH+F+VLTSCK S TP C L+ +I+PHRP N+ESC GK E+ W Sbjct: 732 -LANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALW 790 Query: 859 VEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIF 902 VEE T H ARV DVEL+TGL FYQD+ + VSE+L+LKT+LP F Sbjct: 791 VEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTF 834 >6G4G-A nrPDB Length = 840 Score = 862 bits (2227), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/828 (49%), Positives = 561/828 (67%), Gaps = 16/828 (1%) Query: 85 KEVKSCKGRCFE---RTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRL 141 + + SC+ +CF+ R CRCD+ C G+CC DF++TCV+ T IWTCN FRCGE RL Sbjct: 6 EHIGSCRKKCFDSSHRGLEGCRCDSGCTDRGDCCWDFEDTCVKSTQIWTCNSFRCGETRL 65 Query: 142 SRFVCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDG 201 +CSCADDC DCC +Y +VCQ + WV E C S P+CP F+ PP +LFS+DG Sbjct: 66 EAALCSCADDCLQRKDCCTDYKAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDG 125 Query: 202 FRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKM 261 FRAEYL TW LLP I+KLK CG ++K MR +YPTKTFPNHY+IVTGLYPESHGIIDN M Sbjct: 126 FRAEYLQTWSTLLPNINKLKTCGLHSKYMRAVYPTKTFPNHYTIVTGLYPESHGIIDNNM 185 Query: 262 YDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKV 321 YD +N +FSL S EK NP W+ GQPIW+TA +Q +K+ +Y+WPGSDV ++G P+IY+ Sbjct: 186 YDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRN 245 Query: 322 YNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRL 381 Y+ SVP+E RI +L+WL LP ERP FYT+Y+EEPDS+GH GPVS+ VIKALQ VD Sbjct: 246 YSNSVPYESRIATLLQWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDA 305 Query: 382 VGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRP 441 GMLM+GLK L C+N+I+++DHGM+Q SC + Y+ Y ++ N + GPA R+R Sbjct: 306 FGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEI-NFYMYQGPAPRIRT 364 Query: 442 TDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQ 501 ++P+ +++FN E + ++LSCR+ +QHF+PYL P LPKRLH+AK+ RI+ + +D QW Sbjct: 365 RNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLTPDLPKRLHYAKNVRIDKVHLMVDRQW- 423 Query: 502 LALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGL 561 LA C G HG +N F +M+A+F+ +GP+FK ++ FENIEVYNL+CDLL + Sbjct: 424 LAYRNKGSSNCEGGTHGYNNEFKSMEAIFLAHGPSFKEKTVIEPFENIEVYNLLCDLLHI 483 Query: 562 IPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKS--TSNDLGCTCDPWIVPIKD- 618 PAPNNGSHGSLNHLLK P Y PSH +E + C + + L C+C ++ Sbjct: 484 QPAPNNGSHGSLNHLLKAPFYQPSHAEELSKSAGCGFTTPLPKDSLNCSCLALQTSGQEE 543 Query: 619 -FEKQLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYT 677 ++LNL +V +P+GRPR++ K CLL +++++G+ + MP+W+SYT Sbjct: 544 QVNQRLNLNRGEVSATEKTNLPFGRPRVIQKNKDHCLLYHREYVSGFGKAMKMPMWSSYT 603 Query: 678 FLRNDQFSR--DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYS 735 + S +CL D+R+ S KCS+Y ++ + +GFL PP + + +N Sbjct: 604 VPKPGDTSSLPPTVPDCLRADVRVDPSESQKCSFYLADQNIDHGFLYPPAI-KGNNESQY 662 Query: 736 EALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILK 795 +AL+TSN+VPMY+ F+ +W Y H LL +YA ERNG+NVVSGP+FD++YDG +D+ + + Sbjct: 663 DALITSNLVPMYKEFKKMWDYFHKVLLIKYAIERNGVNVVSGPIFDYNYDGHFDAPDEI- 721 Query: 796 QNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTHGKR 854 + + ++ +PTH+F+VLTSCK + TP C L+ +++PHRP N+ESC K Sbjct: 722 --TNYVAGTDVPVPTHYFVVLTSCKNKTHTPDSCPGWLDVLPFVVPHRPTNVESCPENKA 779 Query: 855 ESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIF 902 E WVEE H ARV DVEL+TGL FYQ++ + VSE+L+LKT+LP F Sbjct: 780 EDLWVEERFKAHIARVRDVELLTGLDFYQEKTQPVSEILQLKTYLPTF 827 >5GZ5-A nrPDB Length = 830 Score = 848 bits (2192), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/827 (50%), Positives = 551/827 (66%), Gaps = 20/827 (2%) Query: 87 VKSCKGRC---FERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSR 143 ++SC+ RC F S C CD C CC D+Q+ CV PT W+CNK RCGEKR++ Sbjct: 8 LESCRNRCNETFSEELSYCSCDNKCTERKACCWDYQDICVLPTQSWSCNKLRCGEKRMAN 67 Query: 144 FVCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFR 203 +CSC++DC T DCC +Y S+C+ + SW+++ C S +CP F+ P +LFS+DGFR Sbjct: 68 VLCSCSEDCLTKKDCCTDYKSICKRETSWLKDQCASSSASQCPEGFDQSPLILFSMDGFR 127 Query: 204 AEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYD 263 AEYL TW L+P I+KLK CGT+ K MR +YPTKTF NHY+IVTGLY E+HGIIDN MYD Sbjct: 128 AEYLETWDTLMPNINKLKTCGTHAKYMRAVYPTKTFVNHYTIVTGLYAETHGIIDNNMYD 187 Query: 264 PKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYN 323 K+N +FSL N W+ GQPIW TA++Q +K+ TYFWPGS+V+I+G P IYKVYN Sbjct: 188 VKLNQNFSLSGSNMRNAAWWGGQPIWHTASYQGLKAATYFWPGSEVKINGSYPTIYKVYN 247 Query: 324 GSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVG 383 S PFE R++ VL+WL LP +RP F TLY+EEPD++GH GPVS +VIK+LQ DR +G Sbjct: 248 KSTPFEARVMEVLKWLDLPKAKRPDFSTLYIEEPDTTGHKFGPVSGQVIKSLQMADRTLG 307 Query: 384 MLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTD 443 MLM+GLK L C+NLIL++DHGME SC + Y+ Y V + + G A R+R + Sbjct: 308 MLMEGLKQRNLHNCVNLILLADHGMEAISCNRLEYMTDYFNTV-DFFMYEGAAPRIRSKN 366 Query: 444 VPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLA 503 VP+ +Y+F+ EA+ K L+CR+P QHF+ YL LPKRLHFA + RI+ + +D QW LA Sbjct: 367 VPKDFYTFDSEAIVKKLTCRKPKQHFKAYLAKDLPKRLHFANNIRIDKVNLMVDRQW-LA 425 Query: 504 LNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIP 563 + + KYC G HG DN F +M+A+F+ +GP FK EV SFENIEVYNLMCDLL L P Sbjct: 426 VRNKKYKYCSGGTHGYDNEFKSMEAIFLAHGPGFKEKTEVTSFENIEVYNLMCDLLKLKP 485 Query: 564 APNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQC---PIKSTSNDLGCTCDPWIVPIKDFE 620 APNNG+HGSLNHLLK P YNPS KE+ C P+ S GC C I ++ Sbjct: 486 APNNGTHGSLNHLLKNPFYNPSPAKEQSPPLYCLFGPVPSPDVS-GCKCSS-ITDLEAVN 543 Query: 621 KQLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTF-- 678 ++LNL + +PYGRP + L+ CLL Q ++++ YS D+LMPLW SYT Sbjct: 544 QRLNLIDQAKMQSEADNLPYGRPHV-LQHSKYCLLHQTKYISAYSQDILMPLWNSYTISK 602 Query: 679 -LRNDQFSRDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEA 737 L + S+CL D+RIP CS Y+ + ++ GFL PP + Y +A Sbjct: 603 SLVKPTSAPPSASDCLRLDVRIPTVQSQTCSNYQPDLAITPGFLYPPDFSSSGPEQY-DA 661 Query: 738 LLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQN 797 L+TSNIVPMY+ F +W+Y H TLL +YA ERNG+NV+SGP+FD++YDG +D + + Q Sbjct: 662 LITSNIVPMYKEFARLWNYFHSTLLPKYATERNGLNVISGPIFDYNYDGHFDPYDTIDQ- 720 Query: 798 SRVIRSQEILIPTHFFIVLTSCKQLSETPLEC--SALESSAYILPHRPDNIESCTHGKRE 855 + + +I IPTH+F+VLTSC+ ++TPL C +L+ ++ILPHRPDN ESC + Sbjct: 721 --YVNNTKIPIPTHYFVVLTSCENSTKTPLNCPPGSLKVLSFILPHRPDNSESCADKSPD 778 Query: 856 SSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIF 902 + WVEE + H ARV DVEL+TGL FY ++ +SE LRLKT LPIF Sbjct: 779 NLWVEERMQTHTARVRDVELLTGLDFYSALKQPLSETLRLKTFLPIF 825 >5OLB-A nrPDB Length = 844 Score = 732 bits (1889), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/833 (44%), Positives = 523/833 (62%), Gaps = 48/833 (5%) Query: 89 SCKGRCFERTF---SNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFV 145 SCKGRCFE +CRCD C S +CC DF E C++ W C K RCGE R Sbjct: 26 SCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 85 Query: 146 CSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAE 205 C C++DC + DCC NY VC+ + WV++ CE I PECPA F PP ++FS+DGFRA Sbjct: 86 CHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRAS 145 Query: 206 YLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 265 Y+ ++P I KL++CGT+ MRP+YPTKTFPN Y++ TGLYPESHGI+ N MYDP Sbjct: 146 YMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 205 Query: 266 MNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGS 325 +A+F L+ +EKFN W+ GQP+W+TA Q V++GT+FW + S Sbjct: 206 FDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFW------------------SVS 247 Query: 326 VPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGML 385 +P E RIL +L+WL LP +ERP Y Y E+PD SGH +GP E+ L+++D+ VG L Sbjct: 248 IPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQL 307 Query: 386 MDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVP 445 MDGLK L L +C+N+I + DHGME +C + +L+ YL +V+++ +V G R+RP +P Sbjct: 308 MDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPK-IP 366 Query: 446 ETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALN 505 ++ +A+ NL+C++P+QHF+PY+K LPKRLH+A + RIE L ++ +W +A Sbjct: 367 NN-LKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARK 425 Query: 506 PSE--RKYCGSGF----HGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLL 559 P + +K G F HG DN ++MQ +F+GYGP FK+ +V FENIE+YN+MCDLL Sbjct: 426 PLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLL 485 Query: 560 GLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIK--STSNDLGCTCDPWIVPIK 617 GL PAPNNG+HGSLNHLL+ + P+ P+E + I + DLGCTCD K Sbjct: 486 GLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDD-----K 540 Query: 618 DFEKQLN--LTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWAS 675 + ++LN L T+ + H+ YGRP +L + + +L F +GYS LMPLW S Sbjct: 541 NKLEELNKRLHTKGSTEERHLL--YGRPAVLYRTSYD-ILYHTDFESGYSEIFLMPLWTS 597 Query: 676 YTFLRNDQFSR--DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHI 733 YT + + S + +NC+ D+R+ C YK++ ++SYGFL PP L+ Sbjct: 598 YTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAK 657 Query: 734 YSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEI 793 Y +A L +N+VPMY +F+ +W Y L+++YA ERNG+NV+SGP+FD++Y+G D + Sbjct: 658 Y-DAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIEDE 716 Query: 794 LKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTHG 852 +KQ + I +PTH++ ++TSC ++ +C L S++ILPHRPDN ESC Sbjct: 717 IKQ---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNSS 773 Query: 853 KRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQE 905 + ES WVEEL+ +H ARV D+E +TGL FY+ S SE+L LKT+L + E Sbjct: 774 EDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYESE 826 >5MHP-A nrPDB Length = 871 Score = 731 bits (1887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/833 (44%), Positives = 521/833 (62%), Gaps = 48/833 (5%) Query: 89 SCKGRCFERTFS---NCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFV 145 SCKGRCFE + +CRCD C S +CC DF E C++ W C K RCGE R Sbjct: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117 Query: 146 CSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAE 205 C C++DC DCC NY VC+ + WV++ CE I ECPA F PP ++FS+DGFRA Sbjct: 118 CHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRAS 177 Query: 206 YLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 265 Y+ ++P I KL++CGT++ MRP+YPTKTFPN Y++ TGLYPESHGI+ N MYDP Sbjct: 178 YMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 237 Query: 266 MNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGS 325 +A+F L+ +EKFN W+ GQP+W+TA Q VK+GT+FW + Sbjct: 238 FDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SVV 279 Query: 326 VPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGML 385 +P E RIL +L+WL LP HERP Y Y E+PD SGH +GP E+ L+++D++VG L Sbjct: 280 IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQL 339 Query: 386 MDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVP 445 MDGLK L L +C+N+I + DHGME +C + +L+ YL +V+++ +V G R+R Sbjct: 340 MDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSN 399 Query: 446 ETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALN 505 Y + +A+ NL+C++P+QHF+PYLK LPKRLH+A + RIE + ++ +W +A Sbjct: 400 NAKY--DPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARK 457 Query: 506 PSE--RKYCGSGF----HGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLL 559 P + +K G F HG DN ++MQ +F+GYGP FK+ +V FENIE+YN+MCDLL Sbjct: 458 PLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLL 517 Query: 560 GLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIK--STSNDLGCTCDPWIVPIK 617 GL PAPNNG+HGSLNHLL+ + P+ P+E + I + DLGCTCD K Sbjct: 518 GLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDD-----K 572 Query: 618 DFEKQLN--LTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWAS 675 + +LN L T+ + H+ YGRP +L + + +L F +GYS LMPLW S Sbjct: 573 NKLDELNKRLHTKGSTEERHLL--YGRPAVLYRTRYD-ILYHTDFESGYSEIFLMPLWTS 629 Query: 676 YTFLRNDQFSR--DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHI 733 YT + + S D ++C+ D+R+ S C YK++ ++SYGFL PP L+ Sbjct: 630 YTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAK 689 Query: 734 YSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEI 793 Y +A L +N+VPMY +F+ +W+Y L+++YA ERNG+NV+SGP+FD+DYDG +D+ + Sbjct: 690 Y-DAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDK 748 Query: 794 LKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTHG 852 +KQ + I +PTH++ ++TSC ++ +C L S++ILPHRPDN ESC Sbjct: 749 IKQ---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSS 805 Query: 853 KRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQE 905 + ES WVEEL+ +H ARV D+E +T L F++ S E+L LKT+L + E Sbjct: 806 EDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESE 858 >4LR2-A nrPDB Length = 401 Score = 244 bits (624), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 151/389 (38%), Positives = 208/389 (53%), Gaps = 21/389 (5%) Query: 192 PPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYP 251 P LL S DGFRA+YL + P + G ++++ ++ TKTFPNHYSIVTGLY Sbjct: 11 PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 68 Query: 252 ESHGIIDNKMYDPKMNASFSLKSKEKFNPLWY-KGQPIWVTANHQEVK-SGTYFWPGSDV 309 ESHGI+ N MYD FS S +K +P W+ + PIWVT QE + S WPG+DV Sbjct: 69 ESHGIVANSMYDAVTKKHFS-DSNDK-DPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDV 126 Query: 310 EIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSS 369 I + + YN SV FEER+ + WL S+ F TLY EEPD+SGH +GP Sbjct: 127 PIHDTISSYFMNYNSSVSFEERLNNITMWLN-NSNPPVTFATLYWEEPDASGHKYGPEDK 185 Query: 370 EVI-KALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNN 428 E + + L+K+D L+G L+ LK LGL + LN+I+ SDHGM Q S + + L+ + Sbjct: 186 ENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYY 245 Query: 429 VKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDR 488 + P A + P N + L P H YLK +P R ++ +DR Sbjct: 246 TLIDLSPVAAILP--------KINRTEVYNKLKNCSP--HMNVYLKEDIPNRFYYQHNDR 295 Query: 489 IEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFEN 548 I+P+ D W + LN S +K G HG DN +M +GPAF G + + Sbjct: 296 IQPIILVADEGWTIVLNESSQKL---GDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINI 352 Query: 549 IEVYNLMCDLLGLIPAPNNGSHGSLNHLL 577 +++Y +MC +LGL P PNNG+ G LL Sbjct: 353 VDIYPMMCHILGLKPHPNNGTFGHTKCLL 381 >5VEN-A nrPDB Length = 416 Score = 233 bits (595), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 138/397 (34%), Positives = 212/397 (53%), Gaps = 20/397 (5%) Query: 190 ESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGL 249 E L+ S DGFR +YL+ P + G + + ++ TKT+PNHY++VTGL Sbjct: 12 EEQKVLVVSFDGFRWDYLYK--VPTPHFHYIMKNGVHVNQVTNVFITKTYPNHYTLVTGL 69 Query: 250 YPESHGIIDNKMYDPKMNASFSLKSKEKFNP-LWYKGQPIWVTANHQEVKSGTYFWPGSD 308 + E+HGI+ N M+DP +N SFSL+ + ++ W + PIW+T SG WPG+D Sbjct: 70 FAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEEATPIWITNQRAGHASGAAMWPGAD 129 Query: 309 VEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVS 368 V+I P Y YN SV FE+R+ ++EW + + + LY EEPD +GH GP S Sbjct: 130 VKIHDSFPTYYLPYNESVSFEDRVAKIIEWFT--AKDPINLGFLYWEEPDDTGHDVGPDS 187 Query: 369 SEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNN 428 + + VD +G L+ LK L +NLI+ SDHGM Q S ++ + L++YL + Sbjct: 188 PLMGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQRVIELDRYLDKEHY 247 Query: 429 VKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDR 488 + + P A + P E + Y+ALA PN Y K +P+R H+ +DR Sbjct: 248 TLIDHSPVAAILPK---EGKFDEVYDALA----GAHPN--LTVYKKEEIPERWHYKHNDR 298 Query: 489 IEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFEN 548 ++P+ D W + N S+ G+ HG DN + M +F+ +GPAF+ ++ + Sbjct: 299 VQPIVAVADEGWYILQNKSDDFLLGN--HGYDNALAEMHPIFLAHGPAFRKNFTKEAMNS 356 Query: 549 IEVYNLMCDLLGLIPAPNNGSHGSLNHLLK----KPI 581 ++Y+L+C LL L P+NGS ++ LL KPI Sbjct: 357 TDLYSLLCHLLNLTALPHNGSFWNVQDLLSSATPKPI 393 >5VEM-A nrPDB Length = 416 Score = 228 bits (582), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 136/385 (35%), Positives = 204/385 (52%), Gaps = 16/385 (4%) Query: 194 TLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPES 253 LL S DGFR +YL+ P + G + K + ++ TKT+PNHY++VTGL+ E+ Sbjct: 16 VLLVSFDGFRWDYLYK--VPTPHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAEN 73 Query: 254 HGIIDNKMYDPKMNASFSLKSKEKFN-PLWYKGQPIWVTANHQEVKSGTYFWPGSDVEID 312 HGI+ N M+DP N SFSL ++ W + PIW+T SG WPG+DV+I Sbjct: 74 HGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTDVKIH 133 Query: 313 GILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVI 372 P Y YN SV FE+R+ ++EW S E + LY E+PD GH GP S + Sbjct: 134 KRFPTHYMPYNESVSFEDRVAKIIEWFT--SKEPINLGLLYWEDPDDMGHHLGPDSPLMG 191 Query: 373 KALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVV 432 + +D+ +G L+ LK L LNLI+ SDHGM Q S ++ + L++YL + + Sbjct: 192 PVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDKDHYTLID 251 Query: 433 YGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPL 492 P A + P E + YEA L+ PN Y K +P+R H+ + RI+P+ Sbjct: 252 QSPVAAILPK---EGKFDEVYEA----LTHAHPN--LTVYKKEDVPERWHYKYNSRIQPI 302 Query: 493 TFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVY 552 D W + N S+ G+ HG DN ++M +F+ +GPAF+ ++ + ++Y Sbjct: 303 IAVADEGWHILQNKSDDFLLGN--HGYDNALADMHPIFLAHGPAFRKNFSKEAMNSTDLY 360 Query: 553 NLMCDLLGLIPAPNNGSHGSLNHLL 577 L+C LL + P+NGS ++ LL Sbjct: 361 PLLCHLLNITAMPHNGSFWNVQDLL 385 >5EGE-A nrPDB Length = 429 Score = 191 bits (484), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 126/403 (31%), Positives = 202/403 (50%), Gaps = 33/403 (8%) Query: 195 LLFSLDGFRAEYLHTWG-GLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPES 253 L+ LDGFR++Y+ LP ++ N G + P +P+ ++PN+Y+++TG + E Sbjct: 27 LVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEV 86 Query: 254 HGIIDNKMYDPKMNASFSLK-SKEKFNPLWYKG-QPIWVTANHQEVKSGTYFWPGSDVEI 311 H +I N M+DP+ N SF + +++ PLW+ G +P+W+T K Y+WPG +VEI Sbjct: 87 HQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEVEI 146 Query: 312 DGILPDI---YKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVS 368 G+ P YK + F + L+ L+ R +Y E D GH +GP S Sbjct: 147 LGVRPTYCLEYKTVPTDINFANAVSDALDSLK---SGRADLAAIYHERIDVEGHHYGPSS 203 Query: 369 SEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGM-EQGSCKKYVYLNKY--LGD 425 + AL+ VD ++ ++ ++D GL + LN+IL SDHGM + K + L+ Y L D Sbjct: 204 PQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDD 263 Query: 426 VNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAK 485 + VK GP L P VP + ++ +H Y K +P R ++ K Sbjct: 264 LQQVKD-RGPVVSLWP--VPGKHSEIYHKL--------RTVEHMTVYEKESIPNRFYYKK 312 Query: 486 SDRIEPLTFYLDPQWQLA---------LNPS-ERKYCGSGFHGSDNLFSNMQALFIGYGP 535 + PLT D W +A +N + +R+ G+HG DN +M+ +F+ GP Sbjct: 313 GKFVSPLTLVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGP 372 Query: 536 AFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLK 578 FK +++VYN+M + G+ P PNNGS + +LK Sbjct: 373 DFKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK 415 >5UDY-A nrPDB Length = 422 Score = 184 bits (467), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 122/392 (31%), Positives = 182/392 (46%), Gaps = 29/392 (7%) Query: 195 LLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESH 254 LL S DGFR Y P + + G + M P + T T P H+++VTG Y E+H Sbjct: 23 LLVSFDGFRWNYDQDVD--TPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENH 80 Query: 255 GIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQ-PIWVTANHQEVKSGTYFWPGSDVEIDG 313 G++ N Y+ + W G PIW+TA Q +++G++F+PG +V G Sbjct: 81 GVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQG 140 Query: 314 IL------PDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPV 367 + I Y + I V+ W + E TLY EPDS+GH +GP Sbjct: 141 VAVTRSRKEGIAHNYKNETEWRANIDTVMAWF---TEEDLDLVTLYFGEPDSTGHRYGPE 197 Query: 368 SSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKK------YVYLNK 421 S E + +++VDR VG L + + L LNLI+ SDHGM + + + N Sbjct: 198 SPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNF 257 Query: 422 YLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRL 481 D+ + YGP L P + E + L P H Y K P+ Sbjct: 258 TFRDIEFELLDYGPNGMLLPKEG-------RLEKVYDALKDAHPKLHV--YKKEAFPEAF 308 Query: 482 HFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGA 541 H+A + R+ PL Y D + ++ +G HG DN +M+ +F GP+F+ G Sbjct: 309 HYANNPRVTPLLMYSDLGY--VIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGL 366 Query: 542 EVDSFENIEVYNLMCDLLGLIPAPNNGSHGSL 573 EV+ FE++ VY LMC LLG++P N+G +L Sbjct: 367 EVEPFESVHVYELMCRLLGIVPEANDGHLATL 398 >1EI6-A nrPDB Length = 406 Score = 53.1 bits (126), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 55/211 (26%), Positives = 87/211 (41%), Gaps = 39/211 (18%) Query: 189 FESPPTLLFSLDGFRAEYLH--TWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIV 246 S PT++ +DG EY++ G P +++L GT + P+ T PN+ SIV Sbjct: 13 LSSAPTIVICVDGCEQEYINQAIQAGQAPFLAELTGFGTVLTG-DCVVPSFTNPNNLSIV 71 Query: 247 TGLYPESHGIIDNKMYDPK------MNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKS- 299 TG P HGI N +D + MN + L++ + GQ + V ++++ Sbjct: 72 TGAPPSVHGICGNFFFDQETQEEVLMNDAKYLRAPTILAEMAKAGQLVAVVTAKDKLRNL 131 Query: 300 ------GTYFWPGS----DVEIDGI----------LPDIYKVYNGSVPFEERILAVLEWL 339 G F ++E G+ +P +Y S E + A L Sbjct: 132 LGHQLKGICFSAEKADQVNLEEHGVENILARVGMPVPSVY-----SADLSEFVFAA--GL 184 Query: 340 QLPSHERPHFYTLYLEEPDSSGHSHGPVSSE 370 L ++ERP F +YL D H H P + E Sbjct: 185 SLLTNERPDF--MYLSTTDYVQHKHAPGTPE 213 >3T02-A nrPDB Length = 427 Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 61/244 (25%), Positives = 94/244 (38%), Gaps = 38/244 (15%) Query: 193 PTLLFSLDGFRAEYLHTW--GGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLY 250 P + LDG YL GL+P + ++K G + + P+ PN+ SI TG Sbjct: 25 PAIAVCLDGCEPAYLDAAIDAGLMPALKRIKERGA-VRLAHSVIPSFANPNNLSIATGSP 83 Query: 251 PESHGIIDNKMYDPK------MNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKS----G 300 P HGI N +Y+P MN L++ F + G + V ++++ G Sbjct: 84 PAVHGICGNYLYEPSTGEEVMMNDPKFLRAPTIFQAFYDAGARVAVVTAKDKLRALLGKG 143 Query: 301 TYFWPGSDV-----EIDGILPDIYKVYNGSV----PFEERILAVLE------WLQLPSHE 345 F G V + D + + N S P E A L ++L Sbjct: 144 LRFDEGRAVCFSSEKSDKATRAEHGIDNASAWLGRPVPEVYSAALSEFVFAAGVKLLREF 203 Query: 346 RPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISD 405 RP +YL D H + P E + DR + L DGL +++ +D Sbjct: 204 RPDI--MYLTTTDYVQHKYAPGVPEANSFYEMFDRYLAEL-DGLG-------AAIVVTAD 253 Query: 406 HGME 409 HGM+ Sbjct: 254 HGMK 257 >3LGD-A nrPDB Length = 508 Score = 35.0 bits (79), Expect = 0.15, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 6/102 (5%) Query: 609 CDPWIVPIKDFEKQL-NLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQ-QQQFLTGYSL 666 C WI+ ++D+ K++ N+T D + + T+ P ++ +V + + F T L Sbjct: 133 CSKWIL-LEDYRKRVQNVTEFDDSLLRNFTLVTQHPEVIYTNQNVVWSKFETIFFTISGL 191 Query: 667 DLLMPLWASYTFLRNDQFSRDDFSNCLYQDLRIPLSPVHKCS 708 P++ Y F +F D N LY ++R L PV++ S Sbjct: 192 IHYAPVFRDYVFRSMQEFYED---NVLYMEIRARLLPVYELS 230 >5TOO-A nrPDB Length = 549 Score = 34.7 bits (78), Expect = 0.21, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 41/98 (41%), Gaps = 13/98 (13%) Query: 193 PTLLFSL--DGFRAEYLHTW------GGLLPVISKLKNCGTYTKNMRPMY-PTKTFPNHY 243 P L+ L D R +YL+ + GG ++ N G N+ Y PT + H Sbjct: 18 PKLVVGLVVDQMRWDYLYRYYSKYGEGGF----KRMLNTGYSLNNVHIDYVPTVSAIGHT 73 Query: 244 SIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPL 281 SI TG P HGI YD ++ S S E P+ Sbjct: 74 SIFTGSVPSIHGIAGADWYDKELGKSVYCTSDETVQPV 111 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Query: 334 AVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGL-KDL 392 A ++ Q+ + F T+ L D GH+ GP S EV ++DR + + L K + Sbjct: 270 AAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKKV 329 Query: 393 GLDKCLNLILISDHG 407 G L + L +DHG Sbjct: 330 GKGNYL-VFLSADHG 343 >5XWI-A nrPDB Length = 567 Score = 34.3 bits (77), Expect = 0.22, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 10/80 (12%) Query: 191 SPPTLL--FSLDGFRAEYLHTW-----GGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHY 243 +PP L+ S+D F A+ + GGL + S+ + + + T+T P H Sbjct: 38 TPPKLIVAISVDQFSADLFSEYRQYYTGGLKRLTSE---GAVFPRGYQSHAATETCPGHS 94 Query: 244 SIVTGLYPESHGIIDNKMYD 263 +I+TG P GII N +D Sbjct: 95 TILTGSRPSRTGIIANNWFD 114 Score = 33.1 bits (74), Expect = 0.57, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Query: 336 LEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLD 395 +E +QL + ++ L D GH+ G +E + ++D +G D L G+D Sbjct: 278 IENMQLGKQAQTDIISIGLSATDYVGHTFGTEGTESCIQVDRLDTELGAFFDKLDKDGID 337 Query: 396 KCLNLILISDHG 407 ++L +DHG Sbjct: 338 YV--VVLTADHG 347 >1E2S-P nrPDB Length = 489 Score = 32.7 bits (73), Expect = 0.66, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 374 ALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG-----MEQGSCKKYVYLNK---YLGD 425 +L ++D VG LM + DLGL + +I +D+G M +G C + K Y G Sbjct: 232 SLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGG 291 Query: 426 VNNVKVVYGPA 436 V + + P Sbjct: 292 VREPALAFWPG 302 >5MI4-A nrPDB Length = 727 Score = 30.0 bits (66), Expect = 4.3, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 24/56 (42%) Query: 605 LGCTCDPWIVPIKDFEKQLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQF 660 + P IV I + Q LT E +++ M L K +HV LQQQ F Sbjct: 495 MNTENKPLIVEITPWVHQFKLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMF 550 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6C01-A nrPDB 1335 0.0 4B56-A nrPDB 1318 0.0 6G4G-A nrPDB 1318 0.0 5GZ5-A nrPDB 1256 0.0 5OLB-A nrPDB 1177 0.0 5MHP-A nrPDB 1155 0.0 5VEN-A nrPDB 532 e-151 5VEM-A nrPDB 531 e-151 4LR2-A nrPDB 487 e-138 5UDY-A nrPDB 466 e-131 5EGE-A nrPDB 465 e-131 3T02-A nrPDB 212 6e-55 1EI6-A nrPDB 191 1e-48 Sequences not found previously or not previously below threshold: 5TOO-A nrPDB 56 7e-08 5XWI-A nrPDB 44 4e-04 2QZU-A nrPDB 43 7e-04 4UPH-A nrPDB 41 0.003 4QAX-A nrPDB 40 0.004 4UOP-A nrPDB 39 0.007 4UPI-A nrPDB 39 0.007 1E2S-P nrPDB 39 0.008 2CQW-A nrPDB 39 0.014 4FDJ-A nrPDB 38 0.024 4UPL-A nrPDB 37 0.040 2VQR-A nrPDB 35 0.15 6BIA-A nrPDB 33 0.56 3LXQ-A nrPDB 33 0.76 1FSU-A nrPDB 32 0.94 1LGN-A nrPDB 32 1.3 4UPK-A nrPDB 32 1.7 4X5S-A nrPDB 32 1.7 2W8S-A nrPDB 31 1.9 2ISN-A nrPDB 31 2.4 4UG4-A nrPDB 30 4.5 5Y1X-A nrPDB 30 4.6 1Q78-A nrPDB 30 5.4 2H32-A nrPDB 29 8.9 >6C01-A nrPDB Length = 838 Score = 1335 bits (3456), Expect = 0.0, Method: Composition-based stats. Identities = 433/830 (52%), Positives = 577/830 (69%), Gaps = 15/830 (1%) Query: 85 KEVKSCKGRCFE---RTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRL 141 ++ SC+ +CF+ R NCRCD AC G+CC DF++TCVE T IW CNKFRCGE RL Sbjct: 12 EKQGSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRL 71 Query: 142 SRFVCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDG 201 +CSC+DDC DCC +Y SVCQ + SW+EE C++ +CP F+ PP +LFS+DG Sbjct: 72 EASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDG 131 Query: 202 FRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKM 261 FRAEYL+TW L+P I+KLK CG ++K MR MYPTKTFPNHY+IVTGLYPESHGIIDN M Sbjct: 132 FRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNM 191 Query: 262 YDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKV 321 YD +N +FSL SKE+ NP W+ GQP+W+TA +Q +K+ TYFWPGS+V I+G P IY Sbjct: 192 YDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMP 251 Query: 322 YNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRL 381 YNGSVPFEERI +L+WL LP ERP FYT+Y EEPDSSGH+ GPVS+ VIKALQ VD Sbjct: 252 YNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHA 311 Query: 382 VGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRP 441 GMLM+GLK L C+N+IL++DHGM+Q C K Y+ Y +N + GPA R+R Sbjct: 312 FGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRA 371 Query: 442 TDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQ 501 ++P ++SFN E + +NLSCR+P+QHF+PYL P LPKRLH+AK+ RI+ + ++D QW Sbjct: 372 HNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW- 430 Query: 502 LALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGL 561 LA+ CG G HG +N F +M+A+F+ +GP+FK EV+ FENIEVYNLMCDLL + Sbjct: 431 LAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRI 490 Query: 562 IPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQC----PIKSTSNDLGCTCDPWIVPIK 617 PAPNNG+HGSLNHLLK P Y PSH +E S C P+ + S D C ++ Sbjct: 491 QPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLE 550 Query: 618 DFEKQLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYT 677 + LNLT E++ + +P+GRPR+L K CLL +++++G+ + MP+W+SYT Sbjct: 551 QVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYT 610 Query: 678 FL--RNDQFSRDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYS 735 + +CL D+R+P S KCS+Y ++ +++GFL PP NR S+ Y Sbjct: 611 VPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQY- 669 Query: 736 EALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILK 795 +AL+TSN+VPMY+ F+ +W Y H LL ++A ERNG+NVVSGP+FD++YDG +D+ + + Sbjct: 670 DALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEIT 729 Query: 796 QNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTHGKR 854 ++ + + ++ IPTH+F+VLTSCK S TP C L+ +I+PHRP N+ESC GK Sbjct: 730 KH---LANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKP 786 Query: 855 ESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQ 904 E+ WVEE T H ARV DVEL+TGL FYQD+ + VSE+L+LKT+LP F Sbjct: 787 EALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFET 836 >4B56-A nrPDB Length = 820 Score = 1318 bits (3410), Expect = 0.0, Method: Composition-based stats. Identities = 820/820 (100%), Positives = 820/820 (100%) Query: 87 VKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVC 146 VKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVC Sbjct: 1 VKSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRFVC 60 Query: 147 SCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEY 206 SCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEY Sbjct: 61 SCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEY 120 Query: 207 LHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKM 266 LHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKM Sbjct: 121 LHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKM 180 Query: 267 NASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSV 326 NASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSV Sbjct: 181 NASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSV 240 Query: 327 PFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLM 386 PFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLM Sbjct: 241 PFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLM 300 Query: 387 DGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPE 446 DGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPE Sbjct: 301 DGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPE 360 Query: 447 TYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNP 506 TYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNP Sbjct: 361 TYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNP 420 Query: 507 SERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPN 566 SERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPN Sbjct: 421 SERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPN 480 Query: 567 NGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPWIVPIKDFEKQLNLT 626 NGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPWIVPIKDFEKQLNLT Sbjct: 481 NGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPWIVPIKDFEKQLNLT 540 Query: 627 TEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLRNDQFSR 686 TEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLRNDQFSR Sbjct: 541 TEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLRNDQFSR 600 Query: 687 DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALLTSNIVPM 746 DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALLTSNIVPM Sbjct: 601 DDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEALLTSNIVPM 660 Query: 747 YQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEI 806 YQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEI Sbjct: 661 YQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQEI 720 Query: 807 LIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLH 866 LIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLH Sbjct: 721 LIPTHFFIVLTSCKQLSETPLECSALESSAYILPHRPDNIESCTHGKRESSWVEELLTLH 780 Query: 867 RARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED 906 RARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED Sbjct: 781 RARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQED 820 >6G4G-A nrPDB Length = 840 Score = 1318 bits (3410), Expect = 0.0, Method: Composition-based stats. Identities = 406/830 (48%), Positives = 560/830 (67%), Gaps = 16/830 (1%) Query: 85 KEVKSCKGRCFE---RTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRL 141 + + SC+ +CF+ R CRCD+ C G+CC DF++TCV+ T IWTCN FRCGE RL Sbjct: 6 EHIGSCRKKCFDSSHRGLEGCRCDSGCTDRGDCCWDFEDTCVKSTQIWTCNSFRCGETRL 65 Query: 142 SRFVCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDG 201 +CSCADDC DCC +Y +VCQ + WV E C S P+CP F+ PP +LFS+DG Sbjct: 66 EAALCSCADDCLQRKDCCTDYKAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDG 125 Query: 202 FRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKM 261 FRAEYL TW LLP I+KLK CG ++K MR +YPTKTFPNHY+IVTGLYPESHGIIDN M Sbjct: 126 FRAEYLQTWSTLLPNINKLKTCGLHSKYMRAVYPTKTFPNHYTIVTGLYPESHGIIDNNM 185 Query: 262 YDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKV 321 YD +N +FSL S EK NP W+ GQPIW+TA +Q +K+ +Y+WPGSDV ++G P+IY+ Sbjct: 186 YDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRN 245 Query: 322 YNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRL 381 Y+ SVP+E RI +L+WL LP ERP FYT+Y+EEPDS+GH GPVS+ VIKALQ VD Sbjct: 246 YSNSVPYESRIATLLQWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDA 305 Query: 382 VGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRP 441 GMLM+GLK L C+N+I+++DHGM+Q SC + Y+ Y ++N + GPA R+R Sbjct: 306 FGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEINF-YMYQGPAPRIRT 364 Query: 442 TDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQ 501 ++P+ +++FN E + ++LSCR+ +QHF+PYL P LPKRLH+AK+ RI+ + +D QW Sbjct: 365 RNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLTPDLPKRLHYAKNVRIDKVHLMVDRQW- 423 Query: 502 LALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGL 561 LA C G HG +N F +M+A+F+ +GP+FK ++ FENIEVYNL+CDLL + Sbjct: 424 LAYRNKGSSNCEGGTHGYNNEFKSMEAIFLAHGPSFKEKTVIEPFENIEVYNLLCDLLHI 483 Query: 562 IPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIKS--TSNDLGCTCDPWIVPI--K 617 PAPNNGSHGSLNHLLK P Y PSH +E + C + + L C+C + Sbjct: 484 QPAPNNGSHGSLNHLLKAPFYQPSHAEELSKSAGCGFTTPLPKDSLNCSCLALQTSGQEE 543 Query: 618 DFEKQLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYT 677 ++LNL +V +P+GRPR++ K CLL +++++G+ + MP+W+SYT Sbjct: 544 QVNQRLNLNRGEVSATEKTNLPFGRPRVIQKNKDHCLLYHREYVSGFGKAMKMPMWSSYT 603 Query: 678 FLRNDQFS--RDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYS 735 + S +CL D+R+ S KCS+Y ++ + +GFL PP + + +N Sbjct: 604 VPKPGDTSSLPPTVPDCLRADVRVDPSESQKCSFYLADQNIDHGFLYPPAI-KGNNESQY 662 Query: 736 EALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILK 795 +AL+TSN+VPMY+ F+ +W Y H LL +YA ERNG+NVVSGP+FD++YDG +D+ + + Sbjct: 663 DALITSNLVPMYKEFKKMWDYFHKVLLIKYAIERNGVNVVSGPIFDYNYDGHFDAPDEI- 721 Query: 796 QNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTHGKR 854 + + ++ +PTH+F+VLTSCK + TP C L+ +++PHRP N+ESC K Sbjct: 722 --TNYVAGTDVPVPTHYFVVLTSCKNKTHTPDSCPGWLDVLPFVVPHRPTNVESCPENKA 779 Query: 855 ESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQ 904 E WVEE H ARV DVEL+TGL FYQ++ + VSE+L+LKT+LP F Sbjct: 780 EDLWVEERFKAHIARVRDVELLTGLDFYQEKTQPVSEILQLKTYLPTFET 829 >5GZ5-A nrPDB Length = 830 Score = 1256 bits (3249), Expect = 0.0, Method: Composition-based stats. Identities = 416/827 (50%), Positives = 550/827 (66%), Gaps = 20/827 (2%) Query: 87 VKSCKGRC---FERTFSNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSR 143 ++SC+ RC F S C CD C CC D+Q+ CV PT W+CNK RCGEKR++ Sbjct: 8 LESCRNRCNETFSEELSYCSCDNKCTERKACCWDYQDICVLPTQSWSCNKLRCGEKRMAN 67 Query: 144 FVCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFR 203 +CSC++DC T DCC +Y S+C+ + SW+++ C S +CP F+ P +LFS+DGFR Sbjct: 68 VLCSCSEDCLTKKDCCTDYKSICKRETSWLKDQCASSSASQCPEGFDQSPLILFSMDGFR 127 Query: 204 AEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYD 263 AEYL TW L+P I+KLK CGT+ K MR +YPTKTF NHY+IVTGLY E+HGIIDN MYD Sbjct: 128 AEYLETWDTLMPNINKLKTCGTHAKYMRAVYPTKTFVNHYTIVTGLYAETHGIIDNNMYD 187 Query: 264 PKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYN 323 K+N +FSL N W+ GQPIW TA++Q +K+ TYFWPGS+V+I+G P IYKVYN Sbjct: 188 VKLNQNFSLSGSNMRNAAWWGGQPIWHTASYQGLKAATYFWPGSEVKINGSYPTIYKVYN 247 Query: 324 GSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVG 383 S PFE R++ VL+WL LP +RP F TLY+EEPD++GH GPVS +VIK+LQ DR +G Sbjct: 248 KSTPFEARVMEVLKWLDLPKAKRPDFSTLYIEEPDTTGHKFGPVSGQVIKSLQMADRTLG 307 Query: 384 MLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTD 443 MLM+GLK L C+NLIL++DHGME SC + Y+ Y V+ + G A R+R + Sbjct: 308 MLMEGLKQRNLHNCVNLILLADHGMEAISCNRLEYMTDYFNTVDFF-MYEGAAPRIRSKN 366 Query: 444 VPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLA 503 VP+ +Y+F+ EA+ K L+CR+P QHF+ YL LPKRLHFA + RI+ + +D QW LA Sbjct: 367 VPKDFYTFDSEAIVKKLTCRKPKQHFKAYLAKDLPKRLHFANNIRIDKVNLMVDRQW-LA 425 Query: 504 LNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDLLGLIP 563 + + KYC G HG DN F +M+A+F+ +GP FK EV SFENIEVYNLMCDLL L P Sbjct: 426 VRNKKYKYCSGGTHGYDNEFKSMEAIFLAHGPGFKEKTEVTSFENIEVYNLMCDLLKLKP 485 Query: 564 APNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQC---PIKSTSNDLGCTCDPWIVPIKDFE 620 APNNG+HGSLNHLLK P YNPS KE+ C P+ S GC C I ++ Sbjct: 486 APNNGTHGSLNHLLKNPFYNPSPAKEQSPPLYCLFGPVPSPDVS-GCKCSS-ITDLEAVN 543 Query: 621 KQLNLTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWASYTFLR 680 ++LNL + +PYGRP +L CLL Q ++++ YS D+LMPLW SYT + Sbjct: 544 QRLNLIDQAKMQSEADNLPYGRPHVLQ-HSKYCLLHQTKYISAYSQDILMPLWNSYTISK 602 Query: 681 ---NDQFSRDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNHIYSEA 737 + S+CL D+RIP CS Y+ + ++ GFL PP + Y +A Sbjct: 603 SLVKPTSAPPSASDCLRLDVRIPTVQSQTCSNYQPDLAITPGFLYPPDFSSSGPEQY-DA 661 Query: 738 LLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQN 797 L+TSNIVPMY+ F +W+Y H TLL +YA ERNG+NV+SGP+FD++YDG +D + + Q Sbjct: 662 LITSNIVPMYKEFARLWNYFHSTLLPKYATERNGLNVISGPIFDYNYDGHFDPYDTIDQ- 720 Query: 798 SRVIRSQEILIPTHFFIVLTSCKQLSETPLECS--ALESSAYILPHRPDNIESCTHGKRE 855 + + +I IPTH+F+VLTSC+ ++TPL C +L+ ++ILPHRPDN ESC + Sbjct: 721 --YVNNTKIPIPTHYFVVLTSCENSTKTPLNCPPGSLKVLSFILPHRPDNSESCADKSPD 778 Query: 856 SSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIF 902 + WVEE + H ARV DVEL+TGL FY ++ +SE LRLKT LPIF Sbjct: 779 NLWVEERMQTHTARVRDVELLTGLDFYSALKQPLSETLRLKTFLPIF 825 >5OLB-A nrPDB Length = 844 Score = 1177 bits (3044), Expect = 0.0, Method: Composition-based stats. Identities = 369/834 (44%), Positives = 523/834 (62%), Gaps = 48/834 (5%) Query: 88 KSCKGRCFERTF---SNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRF 144 SCKGRCFE +CRCD C S +CC DF E C++ W C K RCGE R Sbjct: 25 GSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 84 Query: 145 VCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRA 204 C C++DC + DCC NY VC+ + WV++ CE I PECPA F PP ++FS+DGFRA Sbjct: 85 ACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRA 144 Query: 205 EYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDP 264 Y+ ++P I KL++CGT+ MRP+YPTKTFPN Y++ TGLYPESHGI+ N MYDP Sbjct: 145 SYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 204 Query: 265 KMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNG 324 +A+F L+ +EKFN W+ GQP+W+TA Q V++GT+FW + Sbjct: 205 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFW------------------SV 246 Query: 325 SVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGM 384 S+P E RIL +L+WL LP +ERP Y Y E+PD SGH +GP E+ L+++D+ VG Sbjct: 247 SIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQ 306 Query: 385 LMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDV 444 LMDGLK L L +C+N+I + DHGME +C + +L+ YL +V+++ +V G R+RP + Sbjct: 307 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPK-I 365 Query: 445 PETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLAL 504 P ++ +A+ NL+C++P+QHF+PY+K LPKRLH+A + RIE L ++ +W +A Sbjct: 366 PNN-LKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVAR 424 Query: 505 NPSE--RKYCGS----GFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDL 558 P + +K G G HG DN ++MQ +F+GYGP FK+ +V FENIE+YN+MCDL Sbjct: 425 KPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDL 484 Query: 559 LGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIK--STSNDLGCTCDPWIVPI 616 LGL PAPNNG+HGSLNHLL+ + P+ P+E + I + DLGCTCD Sbjct: 485 LGLKPAPNNGTHGSLNHLLRTNTFRPTLPEEVSRPNYPGIMYLQSDFDLGCTCDD----- 539 Query: 617 KDFEKQLN--LTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWA 674 K+ ++LN L T+ + H+ YGRP +L + + +L F +GYS LMPLW Sbjct: 540 KNKLEELNKRLHTKGSTEERHLL--YGRPAVLYRTSYD-ILYHTDFESGYSEIFLMPLWT 596 Query: 675 SYTFLRNDQFS--RDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNH 732 SYT + + S + +NC+ D+R+ C YK++ ++SYGFL PP L+ Sbjct: 597 SYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEA 656 Query: 733 IYSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLE 792 Y +A L +N+VPMY +F+ +W Y L+++YA ERNG+NV+SGP+FD++Y+G D + Sbjct: 657 KY-DAFLVTNMVPMYPAFKRVWTYFQRVLVKKYASERNGVNVISGPIFDYNYNGLRDIED 715 Query: 793 ILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTH 851 +KQ + I +PTH++ ++TSC ++ +C L S++ILPHRPDN ESC Sbjct: 716 EIKQ---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNDESCNS 772 Query: 852 GKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQE 905 + ES WVEEL+ +H ARV D+E +TGL FY+ S SE+L LKT+L + E Sbjct: 773 SEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYESE 826 >5MHP-A nrPDB Length = 871 Score = 1155 bits (2987), Expect = 0.0, Method: Composition-based stats. Identities = 367/834 (44%), Positives = 520/834 (62%), Gaps = 48/834 (5%) Query: 88 KSCKGRCFERTF---SNCRCDAACVSLGNCCLDFQETCVEPTHIWTCNKFRCGEKRLSRF 144 SCKGRCFE +CRCD C S +CC DF E C++ W C K RCGE R Sbjct: 57 GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116 Query: 145 VCSCADDCKTHNDCCINYSSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRA 204 C C++DC DCC NY VC+ + WV++ CE I ECPA F PP ++FS+DGFRA Sbjct: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176 Query: 205 EYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDP 264 Y+ ++P I KL++CGT++ MRP+YPTKTFPN Y++ TGLYPESHGI+ N MYDP Sbjct: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236 Query: 265 KMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNG 324 +A+F L+ +EKFN W+ GQP+W+TA Q VK+GT+FW + Sbjct: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278 Query: 325 SVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGM 384 +P E RIL +L+WL LP HERP Y Y E+PD SGH +GP E+ L+++D++VG Sbjct: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQ 338 Query: 385 LMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDV 444 LMDGLK L L +C+N+I + DHGME +C + +L+ YL +V+++ +V G R+R Sbjct: 339 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKF- 397 Query: 445 PETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQLAL 504 ++ +A+ NL+C++P+QHF+PYLK LPKRLH+A + RIE + ++ +W +A Sbjct: 398 -SNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVAR 456 Query: 505 NPSE--RKYCGS----GFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFENIEVYNLMCDL 558 P + +K G G HG DN ++MQ +F+GYGP FK+ +V FENIE+YN+MCDL Sbjct: 457 KPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDL 516 Query: 559 LGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQCPIK--STSNDLGCTCDPWIVPI 616 LGL PAPNNG+HGSLNHLL+ + P+ P+E + I + DLGCTCD Sbjct: 517 LGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDD----- 571 Query: 617 KDFEKQLN--LTTEDVDDIYHMTVPYGRPRILLKQHHVCLLQQQQFLTGYSLDLLMPLWA 674 K+ +LN L T+ + H+ YGRP +L + + +L F +GYS LMPLW Sbjct: 572 KNKLDELNKRLHTKGSTEERHLL--YGRPAVLYRTRYD-ILYHTDFESGYSEIFLMPLWT 628 Query: 675 SYTFLRNDQFS--RDDFSNCLYQDLRIPLSPVHKCSYYKSNSKLSYGFLTPPRLNRVSNH 732 SYT + + S D ++C+ D+R+ S C YK++ ++SYGFL PP L+ Sbjct: 629 SYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEA 688 Query: 733 IYSEALLTSNIVPMYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLE 792 Y +A L +N+VPMY +F+ +W+Y L+++YA ERNG+NV+SGP+FD+DYDG +D+ + Sbjct: 689 KY-DAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTED 747 Query: 793 ILKQNSRVIRSQEILIPTHFFIVLTSCKQLSETPLECSA-LESSAYILPHRPDNIESCTH 851 +KQ + I +PTH++ ++TSC ++ +C L S++ILPHRPDN ESC Sbjct: 748 KIKQ---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNS 804 Query: 852 GKRESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHLPIFSQE 905 + ES WVEEL+ +H ARV D+E +T L F++ S E+L LKT+L + E Sbjct: 805 SEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESE 858 >5VEN-A nrPDB Length = 416 Score = 532 bits (1370), Expect = e-151, Method: Composition-based stats. Identities = 132/398 (33%), Positives = 209/398 (52%), Gaps = 16/398 (4%) Query: 190 ESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGL 249 E L+ S DGFR +YL+ P + G + + ++ TKT+PNHY++VTGL Sbjct: 12 EEQKVLVVSFDGFRWDYLYK--VPTPHFHYIMKNGVHVNQVTNVFITKTYPNHYTLVTGL 69 Query: 250 YPESHGIIDNKMYDPKMNASFSLKSKEKFN-PLWYKGQPIWVTANHQEVKSGTYFWPGSD 308 + E+HGI+ N M+DP +N SFSL+ + ++ W + PIW+T SG WPG+D Sbjct: 70 FAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEEATPIWITNQRAGHASGAAMWPGAD 129 Query: 309 VEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVS 368 V+I P Y YN SV FE+R+ ++EW + + + LY EEPD +GH GP S Sbjct: 130 VKIHDSFPTYYLPYNESVSFEDRVAKIIEWFT--AKDPINLGFLYWEEPDDTGHDVGPDS 187 Query: 369 SEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNN 428 + + VD +G L+ LK L +NLI+ SDHGM Q S ++ + L++YL + Sbjct: 188 PLMGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQRVIELDRYLDKEHY 247 Query: 429 VKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDR 488 + + P A + P + ++ + L+ PN Y K +P+R H+ +DR Sbjct: 248 TLIDHSPVAAILPKEG-------KFDEVYDALAGAHPN--LTVYKKEEIPERWHYKHNDR 298 Query: 489 IEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFEN 548 ++P+ D W + N S+ G+ HG DN + M +F+ +GPAF+ ++ + Sbjct: 299 VQPIVAVADEGWYILQNKSDDFLLGN--HGYDNALAEMHPIFLAHGPAFRKNFTKEAMNS 356 Query: 549 IEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSH 586 ++Y+L+C LL L P+NGS ++ LL P Sbjct: 357 TDLYSLLCHLLNLTALPHNGSFWNVQDLLSSATPKPIP 394 >5VEM-A nrPDB Length = 416 Score = 531 bits (1369), Expect = e-151, Method: Composition-based stats. Identities = 132/391 (33%), Positives = 205/391 (52%), Gaps = 16/391 (4%) Query: 190 ESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGL 249 + LL S DGFR +YL+ P + G + K + ++ TKT+PNHY++VTGL Sbjct: 12 DQQKVLLVSFDGFRWDYLYK--VPTPHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGL 69 Query: 250 YPESHGIIDNKMYDPKMNASFSLKSKEKFN-PLWYKGQPIWVTANHQEVKSGTYFWPGSD 308 + E+HGI+ N M+DP N SFSL ++ W + PIW+T SG WPG+D Sbjct: 70 FAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTD 129 Query: 309 VEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVS 368 V+I P Y YN SV FE+R+ ++EW S E + LY E+PD GH GP S Sbjct: 130 VKIHKRFPTHYMPYNESVSFEDRVAKIIEWFT--SKEPINLGLLYWEDPDDMGHHLGPDS 187 Query: 369 SEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNN 428 + + +D+ +G L+ LK L LNLI+ SDHGM Q S ++ + L++YL + Sbjct: 188 PLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDKDHY 247 Query: 429 VKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDR 488 + P A + P + ++ + + L+ PN Y K +P+R H+ + R Sbjct: 248 TLIDQSPVAAILPKEG-------KFDEVYEALTHAHPN--LTVYKKEDVPERWHYKYNSR 298 Query: 489 IEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFEN 548 I+P+ D W + N S+ G+ HG DN ++M +F+ +GPAF+ ++ + Sbjct: 299 IQPIIAVADEGWHILQNKSDDFLLGN--HGYDNALADMHPIFLAHGPAFRKNFSKEAMNS 356 Query: 549 IEVYNLMCDLLGLIPAPNNGSHGSLNHLLKK 579 ++Y L+C LL + P+NGS ++ LL Sbjct: 357 TDLYPLLCHLLNITAMPHNGSFWNVQDLLNS 387 >4LR2-A nrPDB Length = 401 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 151/389 (38%), Positives = 207/389 (53%), Gaps = 21/389 (5%) Query: 192 PPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYP 251 P LL S DGFRA+YL + P + G ++++ ++ TKTFPNHYSIVTGLY Sbjct: 11 PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 68 Query: 252 ESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYK-GQPIWVTANHQEVKS-GTYFWPGSDV 309 ESHGI+ N MYD FS S +K +P W+ PIWVT QE +S WPG+DV Sbjct: 69 ESHGIVANSMYDAVTKKHFS-DSNDK-DPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDV 126 Query: 310 EIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSS 369 I + + YN SV FEER+ + WL S+ F TLY EEPD+SGH +GP Sbjct: 127 PIHDTISSYFMNYNSSVSFEERLNNITMWLN-NSNPPVTFATLYWEEPDASGHKYGPEDK 185 Query: 370 E-VIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNN 428 E + + L+K+D L+G L+ LK LGL + LN+I+ SDHGM Q S + + L+ + Sbjct: 186 ENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSYY 245 Query: 429 VKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDR 488 + P A + P N + L P H YLK +P R ++ +DR Sbjct: 246 TLIDLSPVAAILPK--------INRTEVYNKLKNCSP--HMNVYLKEDIPNRFYYQHNDR 295 Query: 489 IEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVDSFEN 548 I+P+ D W + LN S +K G HG DN +M +GPAF G + + Sbjct: 296 IQPIILVADEGWTIVLNESSQKL---GDHGYDNSLPSMHPFLAAHGPAFHKGYKHSTINI 352 Query: 549 IEVYNLMCDLLGLIPAPNNGSHGSLNHLL 577 +++Y +MC +LGL P PNNG+ G LL Sbjct: 353 VDIYPMMCHILGLKPHPNNGTFGHTKCLL 381 >5UDY-A nrPDB Length = 422 Score = 466 bits (1198), Expect = e-131, Method: Composition-based stats. Identities = 125/426 (29%), Positives = 187/426 (43%), Gaps = 37/426 (8%) Query: 190 ESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGL 249 LL S DGFR Y P + + G + M P + T T P H+++VTG Sbjct: 18 SQNKLLLVSFDGFRWNYDQDVD--TPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGK 75 Query: 250 YPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQ-PIWVTANHQEVKSGTYFWPGSD 308 Y E+HG++ N Y+ + W G PIW+TA Q +++G++F+PG + Sbjct: 76 YIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGN 135 Query: 309 VEIDGIL------PDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGH 362 V G+ I Y + I V+ W + E TLY EPDS+GH Sbjct: 136 VTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWF---TEEDLDLVTLYFGEPDSTGH 192 Query: 363 SHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKK------Y 416 +GP S E + +++VDR VG L + + L LNLI+ SDHGM + + Sbjct: 193 RYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFH 252 Query: 417 VYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPF 476 + N D+ + YGP L P + E + L P H Y K Sbjct: 253 KFPNFTFRDIEFELLDYGPNGMLLPKEG-------RLEKVYDALKDAHPKLH--VYKKEA 303 Query: 477 LPKRLHFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPA 536 P+ H+A + R+ PL Y D + ++ +G HG DN +M+ +F GP+ Sbjct: 304 FPEAFHYANNPRVTPLLMYSDLGY--VIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPS 361 Query: 537 FKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQC 596 F+ G EV+ FE++ VY LMC LLG++P N+G +L +L H + Sbjct: 362 FRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPML--------HTESALPPDGR 413 Query: 597 PIKSTS 602 P Sbjct: 414 PTLLPK 419 >5EGE-A nrPDB Length = 429 Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats. Identities = 126/405 (31%), Positives = 201/405 (49%), Gaps = 33/405 (8%) Query: 193 PTLLFSLDGFRAEYLHTWG-GLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLYP 251 L+ LDGFR++Y+ LP ++ N G + P +P+ ++PN+Y+++TG + Sbjct: 25 KLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHC 84 Query: 252 ESHGIIDNKMYDPKMNASFSLK-SKEKFNPLWYKG-QPIWVTANHQEVKSGTYFWPGSDV 309 E H +I N M+DP+ N SF + +++ PLW+ G +P+W+T K Y+WPG +V Sbjct: 85 EVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPLWITLMKARRKVYMYYWPGCEV 144 Query: 310 EIDGILPDI---YKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGP 366 EI G+ P YK + F + L+ L+ R +Y E D GH +GP Sbjct: 145 EILGVRPTYCLEYKTVPTDINFANAVSDALDSLK---SGRADLAAIYHERIDVEGHHYGP 201 Query: 367 VSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQ-GSCKKYVYLNKY--L 423 S + AL+ VD ++ ++ ++D GL + LN+IL SDHGM K + L+ Y L Sbjct: 202 SSPQRKDALRAVDTVLKYMIQWIQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISL 261 Query: 424 GDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHF 483 D+ VK GP L P VP + ++ +H Y K +P R ++ Sbjct: 262 DDLQQVK-DRGPVVSLWP--VPGKHSEIYHKL--------RTVEHMTVYEKESIPNRFYY 310 Query: 484 AKSDRIEPLTFYLDPQWQLA---------LNPS-ERKYCGSGFHGSDNLFSNMQALFIGY 533 K + PLT D W +A +N + +R+ G+HG DN +M+ +F+ Sbjct: 311 KKGKFVSPLTLVADEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAI 370 Query: 534 GPAFKHGAEVDSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLK 578 GP FK +++VYN+M + G+ P PNNGS + +LK Sbjct: 371 GPDFKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK 415 >3T02-A nrPDB Length = 427 Score = 212 bits (540), Expect = 6e-55, Method: Composition-based stats. Identities = 82/388 (21%), Positives = 133/388 (34%), Gaps = 77/388 (19%) Query: 193 PTLLFSLDGFRAEYLHT--WGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIVTGLY 250 P + LDG YL GL+P + ++K G + + P+ PN+ SI TG Sbjct: 25 PAIAVCLDGCEPAYLDAAIDAGLMPALKRIKERGA-VRLAHSVIPSFANPNNLSIATGSP 83 Query: 251 PESHGIIDNKMYDPK------MNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKS----G 300 P HGI N +Y+P MN L++ F + G + V ++++ G Sbjct: 84 PAVHGICGNYLYEPSTGEEVMMNDPKFLRAPTIFQAFYDAGARVAVVTAKDKLRALLGKG 143 Query: 301 TYFWPGSDV-----EIDGILPDIYKVYNGSV----PFEERILAVLE------WLQLPSHE 345 F G V + D + + N S P E A L ++L Sbjct: 144 LRFDEGRAVCFSSEKSDKATRAEHGIDNASAWLGRPVPEVYSAALSEFVFAAGVKLLREF 203 Query: 346 RPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISD 405 RP +YL D H + P E + DR + L DGL +++ +D Sbjct: 204 RPDI--MYLTTTDYVQHKYAPGVPEANSFYEMFDRYLAEL-DGLG-------AAIVVTAD 253 Query: 406 HGME-----QGSCKKYVYLNKYLGD-------------VNNVKVVYGPAARLRPTDVPET 447 HGM+ GS +Y+ L + + V +G +P+ Sbjct: 254 HGMKPKHKADGSPD-VIYVQDLLDEWLGKDAARVILPITDPYVVHHGALGSFATAYLPDG 312 Query: 448 YYSFNYEALAKNLSCREPNQHFRPYL-KPFLPKRLHFAKSDRIEPLTFYLDPQWQLALNP 506 + + L + Q L + +R + DRI + Sbjct: 313 C---DRSEIMARL---KAIQGVDVVLGREEACRRFELPE-DRIGDIVLV----------S 355 Query: 507 SERKYCGSGFHGSDNLFSNMQALFIGYG 534 SE K G+ H D + + +G Sbjct: 356 SENKTLGTSEHRHD--LAALDEPLRSHG 381 >1EI6-A nrPDB Length = 406 Score = 191 bits (484), Expect = 1e-48, Method: Composition-based stats. Identities = 71/321 (22%), Positives = 119/321 (37%), Gaps = 59/321 (18%) Query: 189 FESPPTLLFSLDGFRAEYLH--TWGGLLPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIV 246 S PT++ +DG EY++ G P +++L GT + P+ T PN+ SIV Sbjct: 13 LSSAPTIVICVDGCEQEYINQAIQAGQAPFLAELTGFGTVLTG-DCVVPSFTNPNNLSIV 71 Query: 247 TGLYPESHGIIDNKMYDPK------MNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKS- 299 TG P HGI N +D + MN + L++ + GQ + V ++++ Sbjct: 72 TGAPPSVHGICGNFFFDQETQEEVLMNDAKYLRAPTILAEMAKAGQLVAVVTAKDKLRNL 131 Query: 300 ------GTYFWPGS----DVEIDGI----------LPDIYKVYNGSVPFEERILAVLEWL 339 G F ++E G+ +P +Y S E + A L Sbjct: 132 LGHQLKGICFSAEKADQVNLEEHGVENILARVGMPVPSVY-----SADLSEFVFAA--GL 184 Query: 340 QLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLN 399 L ++ERP F +YL D H H P + E +D ++ Sbjct: 185 SLLTNERPDF--MYLSTTDYVQHKHAPGTPEANAFYAMMDSYF--------KRYHEQGAI 234 Query: 400 LILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKN 459 + + +DHGM + N + ++ A R R Y ++ AL Sbjct: 235 VAITADHGMNAKT-DAIGRPNILF--LQDLLDAQYGAQRTRVLLPITDPYVVHHGALGS- 290 Query: 460 LSCREPNQHFRPYLKPFLPKR 480 + YL+ +P+R Sbjct: 291 --------YATVYLRDAVPQR 303 >5TOO-A nrPDB Length = 549 Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 40/104 (38%), Gaps = 4/104 (3%) Query: 181 DTPECPAEFESPPTLL-FSLDGFRAEYLHTWGGLLP--VISKLKNCGTYTKNMRPMY-PT 236 P+ P ++ +D R +YL+ + ++ N G N+ Y PT Sbjct: 7 SDPQKTNAVPRPKLVVGLVVDQMRWDYLYRYYSKYGEGGFKRMLNTGYSLNNVHIDYVPT 66 Query: 237 KTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNP 280 + H SI TG P HGI YD ++ S S E P Sbjct: 67 VSAIGHTSIFTGSVPSIHGIAGADWYDKELGKSVYCTSDETVQP 110 Score = 49.3 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 39/258 (15%), Positives = 77/258 (29%), Gaps = 35/258 (13%) Query: 333 LAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDL 392 A ++ Q+ + F T+ L D GH+ GP S EV ++DR + + L Sbjct: 269 DAAIDGNQMGVDDITDFLTVNLASTDYVGHNFGPNSIEVEDTYLRLDRDLADFFNNLDKK 328 Query: 393 GLDKCLNLILISDHGM--EQGSCKKYVYLNKYLGDV------------------------ 426 + L +DHG G + + + + Sbjct: 329 VGKGNYLVFLSADHGAAHSVGFMQAHKMPTGFFVEDMKKEMNAKLKQKFGADNIIAAAMN 388 Query: 427 NNVKVVYGPAA-RLRPTDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAK 485 V A D Y + L ++ + + + R+ Sbjct: 389 YQVYFDRKVLADSKLELDDVRDYVMTELKKEPSVLYVLSTDEIWESSIPEPIKSRVINGY 448 Query: 486 S-DRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEVD 544 + R + + A + + S ++ D+ LF+G+G K G Sbjct: 449 NWKRSGDIQIISKDGYLSAYSKKGTTH--SVWNSYDSHIP---LLFMGWG--IKQGESNQ 501 Query: 545 SFENIEVYNLMCDLLGLI 562 + ++ + LL + Sbjct: 502 PYHMTDIAPTVSSLLKIQ 519 >5XWI-A nrPDB Length = 567 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 4/76 (5%) Query: 192 PPTLLF--SLDGFRAEYLHTWGGL-LPVISKLKNCG-TYTKNMRPMYPTKTFPNHYSIVT 247 PP L+ S+D F A+ + + +L + G + + + T+T P H +I+T Sbjct: 39 PPKLIVAISVDQFSADLFSEYRQYYTGGLKRLTSEGAVFPRGYQSHAATETCPGHSTILT 98 Query: 248 GLYPESHGIIDNKMYD 263 G P GII N +D Sbjct: 99 GSRPSRTGIIANNWFD 114 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 2/72 (2%) Query: 336 LEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLD 395 +E +QL + ++ L D GH+ G +E + ++D +G D L G+ Sbjct: 278 IENMQLGKQAQTDIISIGLSATDYVGHTFGTEGTESCIQVDRLDTELGAFFDKLDKDGI- 336 Query: 396 KCLNLILISDHG 407 ++L +DHG Sbjct: 337 -DYVVVLTADHG 347 >2QZU-A nrPDB Length = 491 Score = 42.8 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 47/340 (13%), Positives = 93/340 (27%), Gaps = 80/340 (23%) Query: 184 ECPAEFESPPTLLFSLDGFRAEYLH---TWGGLLPVISKLKNCGTYTKNMRPMYPTKTFP 240 + + +P + D +R + + P + KL + G N YP + P Sbjct: 20 QAQEKQPTPNLVFIMADQYRGDAIGCIGKEPVKTPHLDKLASEGINFTNAISSYPV-SSP 78 Query: 241 NHYSIVTGLYPESHGIIDN----------------KMYDPKMNA---------SFSLKSK 275 ++TG+YP + N + + + + L + Sbjct: 79 ARGMLMTGMYPIGSKVTGNCNSETAPYGVELSQNARCWSDVLKDQGYNMGYIGKWHLDAP 138 Query: 276 EK--FNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPF----- 328 K + +G+ W E + G W + P + F Sbjct: 139 YKPYVDTYNNRGKVAWNEWCPPERRHGFDHWIAYGTYDYHLKPMYWNTTAPRDSFYYVNQ 198 Query: 329 ---EERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPV------------------ 367 E +E++ ++ F + P +G+ P Sbjct: 199 WGPEYEASKAIEYINGQKDQKQPFALVVSMNPPHTGYELVPDRYKEIYKDLDVEALCKGR 258 Query: 368 ------SSEVIKALQK-----------VDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQ 410 +E+ + VD VG +++ LK L ++ SDHG Sbjct: 259 PDIPAKGTEMGDYFRNNIRNYYACITGVDENVGRIIEALKQNNLFDNTIVVFTSDHG--- 315 Query: 411 GSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYS 450 + K D+ + + P P + Sbjct: 316 ICMGAHENAGK---DIFYEESMRIPMILSWPDQIKPRKSD 352 >4UPH-A nrPDB Length = 547 Score = 40.9 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Query: 186 PAEFESPPTLLFSLDGFRAEYLHT---WGGLLPVISKLKNCGTY-TKNMRPMYPTKTFPN 241 P+ + P LL S D +R + L P + L G T++ P P Sbjct: 40 PSG-KRPNVLLISADQWRGDCLSAVGHASVKTPNVDALAQDGVLFTRHFAGTAP--ASPA 96 Query: 242 HYSIVTGLYPESHGIIDN 259 ++ TGLY +H + N Sbjct: 97 RATLYTGLYQMNHRVCRN 114 Score = 33.9 bits (76), Expect = 0.32, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%) Query: 374 ALQKVDRLVGMLMDGLKDLGLDKCLNLILISDH 406 + +VD +G + LK++G +I SDH Sbjct: 326 MIAEVDTQLGRIWQALKNVGAWDDTLIIFTSDH 358 >4QAX-A nrPDB Length = 513 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 41/108 (37%), Gaps = 18/108 (16%) Query: 339 LQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCL 398 L+ + L PD GHS G + IKA++ VD +G ++D + LD Sbjct: 386 LEELNKGDLDLIILNFANPDMVGHS-GMLEP-TIKAIEAVDECLGEVVDKI----LDMDG 439 Query: 399 NLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVY--GPAARLRPTDV 444 I+ +DHG ++ L D + + P + + Sbjct: 440 YAIITADHG----------NSDQVLTDDDQPMTTHTTNPVPVIVTKEG 477 >4UOP-A nrPDB Length = 442 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 47/143 (32%), Gaps = 20/143 (13%) Query: 303 FWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEW--LQLPSHERPHFYTLYLEEPDSS 360 F P +V + P + + Y + F ++++V +P + +E D Sbjct: 189 FSPSDEVLYNKAFPILEEQYKNNQKFYAQLISVSSHMPFDIPKDK---------QEIDLP 239 Query: 361 GHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLN 420 +A+ D+ +G + LKD G+ ++ DH ++ Sbjct: 240 SDLKDTELGNYFEAVHYADKQLGEFIQKLKDSGIWDDSVVVFYGDH---------HIIKT 290 Query: 421 KYLGDVNNVKVVYGPAARLRPTD 443 L + V + P D Sbjct: 291 DQLPEEQKKYVNRSTQLKAEPAD 313 >4UPI-A nrPDB Length = 576 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 31/98 (31%), Gaps = 9/98 (9%) Query: 170 KSWVEETCESIDTPECPAEFESP-----PTLLFSLDGFRAEYLHTWGGL---LPVISKLK 221 SW E P P L D R +YL +G P I KL Sbjct: 2 ASWSHPQFEKGAETAVPNSSSVPMTQNRNILWIMCDQLRFDYLSCYGHERLNTPNIDKLA 61 Query: 222 NCGTYTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDN 259 G N + T P+ S TG Y SHG N Sbjct: 62 KRGVRFTNAY-VQATVAGPSRMSAYTGRYVRSHGSTQN 98 Score = 38.2 bits (87), Expect = 0.018, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 22/39 (56%) Query: 369 SEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG 407 + ++++D +G L +++ GLD+ ++ +DHG Sbjct: 316 PAYMGLIKQIDDQLGQLFAFMQERGLDENTMIVFTADHG 354 >1E2S-P nrPDB Length = 489 Score = 39.3 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 54/261 (20%), Positives = 77/261 (29%), Gaps = 30/261 (11%) Query: 328 FEERILAVLEWL--QLPSHERPHFYTLYLEE----PDSSGHSHGPVSSE--VIKALQKVD 379 E R +A L +RP F+ Y P SG S S +L ++D Sbjct: 179 LEARYMAFAHDLMADAQRQDRP-FFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELD 237 Query: 380 RLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKK--YVYLNKYLGDVNNVKVVYGPAA 437 VG LM + DLGL + +I +D+G E + L + V PA Sbjct: 238 AAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPAL 297 Query: 438 RLRPTDVPET-----YYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPL 492 P + S + L+ P + P L KS R + L Sbjct: 298 AFWPGHIAPGVTHELASSLDLLPTLAALAGA-PLPNVTLDGFDLSPLLLGTGKSPR-QSL 355 Query: 493 TFYLD-----PQWQLALNP--SERKYCGSGFHGSDNLFSNMQA--LFIGYGPAFKHGAEV 543 FY + H A + P + Sbjct: 356 FFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLYDLSK 415 Query: 544 DSFENIEVYNLMCDLLGLIPA 564 D EN YNL+ + G P Sbjct: 416 DPGEN---YNLLGGVAGATPE 433 >2CQW-A nrPDB Length = 84 Score = 38.6 bits (88), Expect = 0.014, Method: Composition-based stats. Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%) Query: 88 KSCKGRCFERTFSNCRCDAACVSLGNCCLDFQETCVE 124 SC RC C C C LG CC DF + C+E Sbjct: 19 GSCSLRC-GAQDGLCSCHPTCSGLGTCCEDFLDYCLE 54 >4FDJ-A nrPDB Length = 502 Score = 37.8 bits (86), Expect = 0.024, Method: Composition-based stats. Identities = 49/274 (17%), Positives = 85/274 (31%), Gaps = 59/274 (21%) Query: 191 SPP-TLLFSLDGFRAEYLHTWGGL---LPVISKLKNCGTYTKNMRPMYPTKTFPNHYSIV 246 PP LL +D L +G P + ++ G N P P+ +++ Sbjct: 3 QPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANP-LXSPSRAALL 61 Query: 247 TGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTY---- 302 TG P I N Y +A + +E + Q + S Sbjct: 62 TGRLP-----IRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWH 116 Query: 303 ------FWP---GSDVEIDGILPDIYKVYNGSV--------PFEERILAVLEWLQLPSHE 345 F P G D E G + Y+ +E E+ Sbjct: 117 LGHRPQFHPLKHGFD-EWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTG 175 Query: 346 RPHFYTLYLEEP-DS----SGHS-----------HGP--------VSSEVI---KALQKV 378 + +YL+E D + H H P +S+ A++++ Sbjct: 176 EANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREI 235 Query: 379 DRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGS 412 D +G +++ L+DL + + SD+G S Sbjct: 236 DDSIGKILELLQDLHVADNTFVFFTSDNGAALIS 269 >4UPL-A nrPDB Length = 569 Score = 37.0 bits (84), Expect = 0.040, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 35/119 (29%), Gaps = 13/119 (10%) Query: 178 ESIDTPECPAEFESP--PTLLFSLDGFRAEYLHTWGGL---LPVISKLKNCGTYTKNMRP 232 S P+ E+ L D R +YL +G P I +L G Sbjct: 2 ASWSHPQFEKGAETAVMNILFIMFDQLRWDYLSCYGHKTLNTPHIDRLAAKGVRFDRAYI 61 Query: 233 MYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVT 291 P + S TG Y SHG N + + + L G W+ Sbjct: 62 QSPICGS-SRMSTYTGRYVHSHGASWNGI-------PLKVGEMTMGDHLRAAGMGCWLV 112 Score = 36.6 bits (83), Expect = 0.055, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 36/104 (34%), Gaps = 3/104 (2%) Query: 369 SEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG--MEQGSCKKYVYLNKYLGDV 426 + +++ D +G L L+D G + ++L SDHG + + + + V Sbjct: 307 PAYMGLIKQADDQMGRLFKWLEDTGRMQDTMIVLTSDHGDFLGDHWMGEKTFFHDASTRV 366 Query: 427 NNVKVVYGPAA-RLRPTDVPETYYSFNYEALAKNLSCREPNQHF 469 + P A R + S + + +P H Sbjct: 367 PLIIYDPRPEADATRGSVCDALVESIDLAPTFVEAAGGKPAMHI 410 >2VQR-A nrPDB Length = 543 Score = 35.1 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 42/232 (18%), Positives = 70/232 (30%), Gaps = 22/232 (9%) Query: 375 LQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCK---KYVYLNKYLGDVNNVKV 431 + +VD +G + L + G +I SDHG + G K Y + + V Sbjct: 323 ITEVDDCLGRVFSYLDETGQWDDTLIIFTSDHGEQLGDHHLLGKIGYNDPSFR-IPLVIK 381 Query: 432 VYGPAARLRPTDVPETYYSFNYEALAKNLSCREPN----QHFRPYLKPFLPKRL----HF 483 G AR + T + L + P+ P+L P+ H+ Sbjct: 382 DAGENARAGAIESGFTESIDVMPTILDWLGGKIPHACDGLSLLPFLSEGRPQDWRTELHY 441 Query: 484 AKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNLFSNMQALFIGYGPAFKHGAEV 543 R +Y +PQ L L ++ C D + + F P F Sbjct: 442 EYDFRD---VYYSEPQSFLGLGMNDCSLCVIQ----DERYKYVH--FAALPPLF-FDLRH 491 Query: 544 DSFENIEVYNLMCDLLGLIPAPNNGSHGSLNHLLKKPIYNPSHPKEEGFLSQ 595 D E + + + L H + + S P+ S Sbjct: 492 DPNEFTNLADDPAYAALVRDYAQKALSWRLKHADRTLTHYRSGPEGLSERSH 543 >6BIA-A nrPDB Length = 477 Score = 33.2 bits (74), Expect = 0.56, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 26/75 (34%), Gaps = 1/75 (1%) Query: 374 ALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVY 433 + VDR VG L++ LK ++ +SD+G + S + K Sbjct: 257 MVYAVDRGVGKLVEALKKNNQYDNTLIVFMSDNG-GKLSKGANNFPLKAGKGSTQEGGFR 315 Query: 434 GPAARLRPTDVPETY 448 P P VP Sbjct: 316 VPMLFHWPKHVPAGK 330 >3LXQ-A nrPDB Length = 450 Score = 32.8 bits (73), Expect = 0.76, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 29/89 (32%), Gaps = 8/89 (8%) Query: 326 VPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSE--------VIKALQK 377 V E+ E + S F++L + S + + E A++ Sbjct: 218 VSDEDLYNKADEEFERLSKGDKPFFSLVFTSSNHSPYEYPEGKIEQYDSEHMTRNNAVKY 277 Query: 378 VDRLVGMLMDGLKDLGLDKCLNLILISDH 406 D +G D K I+I+DH Sbjct: 278 SDYALGTFFDKAKKSSYWDDTIFIVIADH 306 >1FSU-A nrPDB Length = 492 Score = 32.4 bits (72), Expect = 0.94, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 29/92 (31%), Gaps = 7/92 (7%) Query: 316 PDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKAL 375 I + N + L+ + P + Y D + H + + Sbjct: 177 RAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYA-------GMV 229 Query: 376 QKVDRLVGMLMDGLKDLGLDKCLNLILISDHG 407 +D VG + LK GL I +D+G Sbjct: 230 SLMDEAVGNVTAALKSSGLWNNTVFIFSTDNG 261 >1LGN-A nrPDB Length = 204 Score = 32.0 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 38/115 (33%), Gaps = 8/115 (6%) Query: 243 YSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQEVKSGTY 302 YS+ G + + +I+ + ++ S +S W G P+ + ++ G + Sbjct: 71 YSLYIGRHKVTSKVIEK--FPAPVHICVSWESSSGIAEFWINGTPL----VKKGLRQGYF 124 Query: 303 FWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERPHFYTLYLEEP 357 + + ++ S F I + W + + + Y P Sbjct: 125 VEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYMWDSVL--PPENILSAYQGTP 177 >4UPK-A nrPDB Length = 538 Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 26/59 (44%) Query: 377 KVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGP 435 +VD +G ++ LK+ G +++ +DHG G + + Y + ++ P Sbjct: 319 EVDTHIGRVIAHLKETGQYDDTLIVVTADHGEMLGDRHSWGKMTVYDAAYHTPLIIRAP 377 >4X5S-A nrPDB Length = 232 Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 24/72 (33%), Gaps = 2/72 (2%) Query: 442 TDVPETYYSFNYEALAKNLSCREPNQHFRPYLKPFLPKRLHFAKSDRIEPLTFYLDPQWQ 501 + PE + N E NL + P Y ++LH + + P ++ Sbjct: 15 ENGPENWAKLNPEYFWCNLKNQSPVDISDNYKVHAKLEKLHINYNKAVNP--EIVNNGHT 72 Query: 502 LALNPSERKYCG 513 + +N E Sbjct: 73 IQVNVLEDFKLN 84 >2W8S-A nrPDB Length = 543 Score = 31.2 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 375 LQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG 407 + ++D +G + L + G +I SDHG Sbjct: 323 ITEIDDCLGRVFAYLDETGQWDDTLIIFTSDHG 355 >2ISN-A nrPDB Length = 364 Score = 30.9 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 33/79 (41%), Gaps = 2/79 (2%) Query: 746 MYQSFQVIWHYLHDTLLQRYAHERNGINVVSGPVFDFDYDGRYDSLEILKQNSRVIRSQE 805 +Y+ + W Y+ D + + + V+ V D+ YD +S + + +QE Sbjct: 279 VYEPSGMDWAYVRDLTVAEMQRSKGDLEEVAARVMDYAYD--MNSQDNISVMLVAFHNQE 336 Query: 806 ILIPTHFFIVLTSCKQLSE 824 + PT + V++ E Sbjct: 337 VEHPTAVYKVVSGQVDKVE 355 >4UG4-A nrPDB Length = 515 Score = 30.1 bits (66), Expect = 4.5, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%) Query: 375 LQKVDRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYG 434 + +D VG L+D L + ++ SDHG G + +N + G ++ G Sbjct: 269 ISYLDEKVGELIDTLTRTRMLDDTLILFCSDHGDMLGERGLWFKMNFFEGSARVPLMIAG 328 Query: 435 P 435 P Sbjct: 329 P 329 >5Y1X-A nrPDB Length = 914 Score = 30.1 bits (66), Expect = 4.6, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Query: 854 RESSWVEELLTLHRARVTDVELITGLSFYQDRQESVSELLRLKTHL 899 RE+ + EE+ R++ V+L+ + F +D +S +R ++++ Sbjct: 354 RENLFSEEMTKTVTTRLSHVDLLRSVQFLEDSS-PLSHPIRPESYV 398 >1Q78-A nrPDB Length = 514 Score = 29.7 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 32/84 (38%) Query: 572 SLNHLLKKPIYNPSHPKEEGFLSQCPIKSTSNDLGCTCDPWIVPIKDFEKQLNLTTEDVD 631 +LN + P NPS + ++ + +V +++F++ L +T E + Sbjct: 294 NLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTRMVMVEEFKQGLAITDEILL 353 Query: 632 DIYHMTVPYGRPRILLKQHHVCLL 655 + + P K H +L Sbjct: 354 SKAEWSKLFEAPNFFQKYKHYIVL 377 >2H32-A nrPDB Length = 126 Score = 28.9 bits (63), Expect = 8.9, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 15/48 (31%), Gaps = 3/48 (6%) Query: 338 WLQLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGML 385 W Q P F Y + D S GP + V R G L Sbjct: 37 WYQQRPGHPPRFLLRYFSQSDKSQ---GPQVPPRFSGSKDVARNRGYL 81 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.129 0.382 Lambda K H 0.267 0.0407 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,502,711 Number of Sequences: 36641 Number of extensions: 1507256 Number of successful extensions: 3543 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 3289 Number of HSP's gapped (non-prelim): 81 length of query: 906 length of database: 10,336,785 effective HSP length: 106 effective length of query: 800 effective length of database: 6,452,839 effective search space: 5162271200 effective search space used: 5162271200 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 64 (29.3 bits)