BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P06761 (654 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5E84-A nrPDB 1208 0.0 5FPN-A nrPDB 807 0.0 5TKY-A nrPDB 620 e-178 4JN4-A nrPDB 565 e-161 4RTF-D nrPDB 561 e-160 4ANI-C nrPDB 550 e-157 5OBV-A nrPDB 507 e-144 2QXL-A nrPDB 241 6e-64 5MB9-A nrPDB 187 2e-47 1JCE-A nrPDB 62 6e-10 4CZI-A nrPDB 51 1e-06 3H1Q-A nrPDB 38 0.012 5EOY-A nrPDB 33 0.42 4TU3-X nrPDB 32 0.60 1NBW-A nrPDB 32 1.1 3LWT-X nrPDB 32 1.1 6IRV-A nrPDB 31 1.3 5LJV-A nrPDB 31 2.1 2G3M-A nrPDB 31 2.2 5SVC-B nrPDB 30 3.4 6IRX-A nrPDB 30 3.9 1H1Z-A nrPDB 29 5.9 3IA5-A nrPDB 29 6.4 >5E84-A nrPDB Length = 606 Score = 1208 bits (3126), Expect = 0.0, Method: Compositional matrix adjust. Identities = 599/609 (98%), Positives = 600/609 (98%), Gaps = 4/609 (0%) Query: 25 EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL 84 EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL Sbjct: 2 EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL 61 Query: 85 TSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEE 144 TSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEE Sbjct: 62 TSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEE 121 Query: 145 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA 204 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA Sbjct: 122 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA 181 Query: 205 AAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 264 AAIAYGLDKREGEKNILVFDLGGG FDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME Sbjct: 182 AAIAYGLDKREGEKNILVFDLGGGAFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 241 Query: 265 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTR 324 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESF+EGEDFSETLTR Sbjct: 242 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTR 301 Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 384 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP Sbjct: 302 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 361 Query: 385 SRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444 SRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP Sbjct: 362 SRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 421 Query: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504 TKKSQIFS TVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID Sbjct: 422 TKKSQIFSVGG----TVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 477 Query: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE Sbjct: 478 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 537 Query: 565 LESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 624 LESYAYSLKNQIGDKEKLGGKLS EDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE Sbjct: 538 LESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 597 Query: 625 EIVQPIISK 633 EIVQPIISK Sbjct: 598 EIVQPIISK 606 >5FPN-A nrPDB Length = 640 Score = 807 bits (2084), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/613 (64%), Positives = 494/613 (80%), Gaps = 8/613 (1%) Query: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 G +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+ N Sbjct: 6 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 64 Query: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147 P NT+FDAKRLIGR + D +VQ D+K PF+VV + KP +QV+ G +TKTF PEEIS+ Sbjct: 65 PTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKG-ETKTFFPEEISS 123 Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207 MVLTKMKE AEAYLG KV AV+TVPAYFND+QRQATKDAGTI GLNV+RIINEPTAAAI Sbjct: 124 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 183 Query: 208 AYGLDKRE---GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 264 AYGLDK+ GEKN+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ Sbjct: 184 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 243 Query: 265 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTR 324 H + +K+K KD+ + RAV++LR E+AKR LSS QA IEI+S +EG DF ++TR Sbjct: 244 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 303 Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 384 A+FEELN DLFR T++PV+K L D+ L K I EIVLVGGSTRIPKIQ+L+++FFNGKE Sbjct: 304 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 363 Query: 385 SRGINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTV 442 ++ INPDEAVAYGAAVQA +L GD ++ DL+LLDV PL+LGIET GGVMT LI RNT Sbjct: 364 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 423 Query: 443 VPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFE 502 +PTK++Q F+T SDNQ +V ++VYEGER +TKDN+LLG FDLTGIPPAPRGVPQIEVTF+ Sbjct: 424 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 483 Query: 503 IDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTR 562 ID NGIL VTA DK TG +NKITITND+ RL+ ++I+RMV +AE++ ED+ ++R+ + Sbjct: 484 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 543 Query: 563 NELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKE 622 N LESY Y++K + D EKL GK+S +DK + +E I WL+ +Q A+ ++++ K+KE Sbjct: 544 NALESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKE 602 Query: 623 LEEIVQPIISKLY 635 LE + PIISKLY Sbjct: 603 LERVCNPIISKLY 615 >5TKY-A nrPDB Length = 621 Score = 620 bits (1600), Expect = e-178, Method: Compositional matrix adjust. Identities = 333/602 (55%), Positives = 434/602 (72%), Gaps = 9/602 (1%) Query: 31 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90 +GIDLGTTYSCV V++ VEIIAN+QGN TPS+V+FT E RLIG+AAKNQ NP N Sbjct: 17 IGIDLGTTYSCVAVYEGTNVEIIANEQGNFTTPSFVSFT-ENCRLIGEAAKNQAAMNPAN 75 Query: 91 TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150 T+FD KRLIGR ++DP+V++D++ PFKVV+ P ++V G QT TF+P+EISAMVL Sbjct: 76 TIFDVKRLIGRRFDDPTVKKDMESWPFKVVDDNGNPKVEVQYLG-QTHTFSPQEISAMVL 134 Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210 TKMKE AE LGKKV AV+TVPAYFND QRQATKDAG IAGLNV+RIINEPTAAAIAYG Sbjct: 135 TKMKEIAETKLGKKVEKAVITVPAYFNDNQRQATKDAGAIAGLNVLRIINEPTAAAIAYG 194 Query: 211 LD--KREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIK 268 L K + E+N+L++DLGGG FDVSLL I GVF V AT GDTHLGG+DFD ++E+ K Sbjct: 195 LGSGKSDKERNVLIYDLGGGAFDVSLLNIQGGVFTVKATAGDTHLGGQDFDTNLLEYCKK 254 Query: 269 LYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFE 328 + +KT KD+ D RA+++LR E+AKR LSS Q IEI+S F+GEDF+ +TRA+FE Sbjct: 255 EFTRKTKKDLSGDARALRRLRTACERAKRTLSSGAQTTIEIDSLFDGEDFNIQITRARFE 314 Query: 329 ELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGI 388 +LN F T++PV +VL+D+ ++K +DEIVLVGGSTRIP+IQ+L+ EFF+GK+ + I Sbjct: 315 DLNAKAFAGTLEPVAQVLKDAGIEKHQVDEIVLVGGSTRIPRIQKLLSEFFDGKKLEKSI 374 Query: 389 NPDEAVAYGAAVQAGVLSG---DQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPT 445 NPDEAVAYGAAVQAG+LSG DT DL+LLDV PL+LG+ G + ++PR VPT Sbjct: 375 NPDEAVAYGAAVQAGILSGKATSADTSDLLLLDVVPLSLGVAMEGNIFAPVVPRGQTVPT 434 Query: 446 KKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDV 505 K + F+T +DNQ TV VY+GER +DN LLG F L IPP G P +EV FE+DV Sbjct: 435 IKKRTFTTVADNQQTVQFPVYQGERVNCEDNTLLGEFTLAPIPPMKAGEPVLEVVFEVDV 494 Query: 506 NGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNEL 565 NGIL+VTA +K +G ITI N +L+ +EIE+M++DAEKF + + +R + + +L Sbjct: 495 NGILKVTATEKTSGRSANITIANSVGKLSTDEIEKMISDAEKFKSKCEAFSKRFEAKQQL 554 Query: 566 ESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEE 625 ESY ++ I D L KL K+ +E+A+ E + LE +D+ ++ K K+ L+ Sbjct: 555 ESYISRVEEIISDP-TLSLKLKRGQKDKIEQALSEAMAQLE-IEDSTADELKKKELALKR 612 Query: 626 IV 627 +V Sbjct: 613 LV 614 >4JN4-A nrPDB Length = 608 Score = 565 bits (1456), Expect = e-161, Method: Compositional matrix adjust. Identities = 305/613 (49%), Positives = 409/613 (66%), Gaps = 28/613 (4%) Query: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 G ++GIDLGTT SCV + ++ N +G+R TPS +A+T +GE L+G AK Q +N Sbjct: 2 GKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTN 61 Query: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKT-KPYIQVDIGGGQTKTFAPEEIS 146 P+NT+F KRLIGR + D VQ+D+ +PFK++ +++V + + AP +IS Sbjct: 62 PQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEV-----KGQKMAPPQIS 116 Query: 147 AMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAA 206 A VL KMK+TAE YLG+ VT AV+TVPAYFNDAQRQATKDAG IAGL V RIINEPTAAA Sbjct: 117 AEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAA 176 Query: 207 IAYGLDKREGEKNILVFDLGGGTFDVSLLTID----NGVFEVVATNGDTHLGGEDFDQRV 262 +AYGLDK G + I V+DLGGG FD+S++ ID FEV+ATNGDTHLGGEDFD R+ Sbjct: 177 LAYGLDKGTGNRTIAVYDLGGGAFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236 Query: 263 MEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEG----EDF 318 + + ++ +KK G D+R D A+Q+L+ EKAK LSS Q + + + Sbjct: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHM 296 Query: 319 SETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEF 378 + +TRAK E L DL +++P++ L+D+ L SDID+++LVGG TR+P +Q+ V EF Sbjct: 297 NIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEF 356 Query: 379 FNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIP 438 F GKEP + +NPDEAVA GAAVQ GVL+G D D++LLDV PL+LGIET+GGVMT LI Sbjct: 357 F-GKEPRKDVNPDEAVAIGAAVQGGVLTG--DVKDVLLLDVTPLSLGIETMGGVMTTLIA 413 Query: 439 RNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIE 498 +NT +PTK SQ+FS VTI V +GER DN LG F+L GI PAPRG+PQIE Sbjct: 414 KNTTIPTKHSQVFSMGG----AVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIE 469 Query: 499 VTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKER 558 VTF+ID +GIL V+A+DK +G + KITI L +EI++MV DAE AE D+K +E Sbjct: 470 VTFDIDADGILHVSAKDKNSGKEQKITIKASSG-LNEDEIQKMVRDAEANAEADRKFEEL 528 Query: 559 IDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKA 618 + TRN+ + +S + Q+ E+ G KL +DK +E A+ L+ A IE A Sbjct: 529 VQTRNQGDHLLHSTRKQV---EEAGDKLPADDKTAIESALTALETALKGEDKAAIE---A 582 Query: 619 KKKELEEIVQPII 631 K +EL ++ Q ++ Sbjct: 583 KMQELAQVSQKLM 595 >4RTF-D nrPDB Length = 546 Score = 561 bits (1445), Expect = e-160, Method: Compositional matrix adjust. Identities = 294/541 (54%), Positives = 371/541 (68%), Gaps = 36/541 (6%) Query: 31 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90 VGIDLGTT S V V + G ++AN +G+R TPS VAF GE L+G AKNQ +N + Sbjct: 37 VGIDLGTTNSVVSVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVTNVDR 96 Query: 91 TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150 TV KR +G W+ I++D K + EISA +L Sbjct: 97 TVRSVKRHMGSDWS-----------------------IEID-----GKKYTAPEISARIL 128 Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210 K+K AEAYLG+ +T AV+T PAYFNDAQRQATKDAG IAGLNV+RI+NEPTAAA+AYG Sbjct: 129 MKLKRDAEAYLGEDITDAVITTPAYFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAYG 188 Query: 211 LDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLY 270 LDK E E+ ILVFDLGGGTFDVSLL I GV EV AT+GD HLGG+D+DQRV++ + + Sbjct: 189 LDKGEKEQRILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDQRVVDWLVDKF 248 Query: 271 KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGED-----FSETLTRA 325 K +G D+ KD A+Q+LR EKAK LSS I + D E LTRA Sbjct: 249 KGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRA 308 Query: 326 KFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPS 385 +F+ + DL T KP Q V+ D+ + S+ID +VLVGGSTR+P + LVKE GKEP+ Sbjct: 309 EFQRITQDLLDRTRKPFQSVIADTGISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKEPN 368 Query: 386 RGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPT 445 +G+NPDE VA GAA+QAGVL G + D++LLDV PL+LGIET GGVMT+LI RNT +PT Sbjct: 369 KGVNPDEVVAVGAALQAGVLKG--EVKDVLLLDVTPLSLGIETKGGVMTRLIERNTTIPT 426 Query: 446 KKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDV 505 K+S+ F+TA DNQP+V I+VY+GER + N LLG+F+LTGIPPAPRG+PQIEVTF+ID Sbjct: 427 KRSETFTTADDNQPSVQIQVYQGEREIAAHNKLLGSFELTGIPPAPRGIPQIEVTFDIDA 486 Query: 506 NGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNEL 565 NGI+ VTA+DKGTG +N I I + + L+ E+I+RM+ DAE AEED+K +E D RN+ Sbjct: 487 NGIVHVTAKDKGTGKENTIRI-QEGSGLSKEDIDRMIKDAEAHAEEDRKRREEADVRNQA 545 Query: 566 E 566 E Sbjct: 546 E 546 >4ANI-C nrPDB Length = 509 Score = 550 bits (1417), Expect = e-157, Method: Compositional matrix adjust. Identities = 292/539 (54%), Positives = 376/539 (69%), Gaps = 39/539 (7%) Query: 30 VVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPE 89 ++GIDLGTT SCV V + G V++I N +GNR TPS VAF GERL+G+ AK Q +NP Sbjct: 4 IIGIDLGTTNSCVAVLEGGEVKVIPNPEGNRTTPSVVAFK-NGERLVGEVAKRQAITNP- 61 Query: 90 NTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMV 149 NT+ KR +G + +V+I G K + P+EISA++ Sbjct: 62 NTIISIKRHMGTDY-------------------------KVEIEG---KQYTPQEISAII 93 Query: 150 LTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAY 209 L +K AE YLG+ VT AV+TVPAYFNDAQRQATKDAG IAGL V RIINEPTAAA+AY Sbjct: 94 LQYLKSYAEDYLGEPVTRAVITVPAYFNDAQRQATKDAGRIAGLEVERIINEPTAAALAY 153 Query: 210 GLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKL 269 GLDK E ++ ILV+DLGGGTFDVS+L + +GVFEV AT GD HLGG+DFDQ ++++ + Sbjct: 154 GLDKEE-DQTILVYDLGGGTFDVSILELGDGVFEVKATAGDNHLGGDDFDQVIIDYLVNQ 212 Query: 270 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGED----FSETLTRA 325 +K++ G D+ KD A+Q+L+ EKAK+ LS Q +I + E+ TLTRA Sbjct: 213 FKQEHGIDLSKDKMALQRLKDAAEKAKKELSGVTQTQISLPFISANENGPLHLEMTLTRA 272 Query: 326 KFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPS 385 KFEEL+ L TM PV++ L+D+ L +DID+++LVGGSTRIP +Q+ +K GKEP Sbjct: 273 KFEELSAHLVERTMGPVRQALQDAGLTPADIDKVILVGGSTRIPAVQEAIKREL-GKEPH 331 Query: 386 RGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPT 445 +G+NPDE VA GAA+Q GV++G+ D+VLLDV PL+LGIET+GGV TKLI RNT +PT Sbjct: 332 KGVNPDEVVAIGAAIQGGVIAGE--VKDVVLLDVTPLSLGIETMGGVFTKLIERNTTIPT 389 Query: 446 KKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDV 505 KSQ+F+TA+DNQ TV I V +GERP+ DN LG F LTGIPPAPRGVPQIEVTF+ID Sbjct: 390 SKSQVFTTAADNQTTVDIHVLQGERPMAADNKSLGRFQLTGIPPAPRGVPQIEVTFDIDA 449 Query: 506 NGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564 NGI+ V A+D GT + ITI + L+ EEI+RM+ +AE+ AE D+K KE + RNE Sbjct: 450 NGIVHVRAKDLGTNKEQSITIKSSSG-LSEEEIQRMIKEAEENAEADRKRKEAAELRNE 507 >5OBV-A nrPDB Length = 529 Score = 507 bits (1306), Expect = e-144, Method: Compositional matrix adjust. Identities = 273/547 (49%), Positives = 366/547 (66%), Gaps = 35/547 (6%) Query: 26 DVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLT 85 D G ++GIDLGTT SCV V + GR ++ N +G R TPS V++ E ++GDAAK Q+ Sbjct: 4 DNGLIIGIDLGTTNSCVSVMEGGRPVVLENPEGKRTTPSIVSYK-NNEIIVGDAAKRQMV 62 Query: 86 SNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEI 145 +NP NT+ KRL+G T ++V G TK +PE++ Sbjct: 63 TNP-NTIVSIKRLMG-----------------------TSNKVKVQNADGTTKELSPEQV 98 Query: 146 SAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAA 205 SA +L+ +K+ AE +GKK++ AV+TVPAYFNDA+R ATK AG IAGLNV RIINEPTAA Sbjct: 99 SAQILSYLKDFAEKKIGKKISRAVITVPAYFNDAERNATKTAGKIAGLNVERIINEPTAA 158 Query: 206 AIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEH 265 A+AYG+DK E +LV+DLGGGTFDVSLL I G FEV+AT GD LGG+D+D +++E Sbjct: 159 ALAYGIDKASREMKVLVYDLGGGTFDVSLLDIAEGTFEVLATAGDNRLGGDDWDNKIIE- 217 Query: 266 FIKLY--KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGE----DFS 319 +I Y K+ G ++ KD A+Q+L+ E+AK LS+Q + I + + + Sbjct: 218 YISAYIAKEHQGLNLSKDKMAMQRLKEAAERAKIELSAQLETIISLPFLTVTQKGPVNVE 277 Query: 320 ETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFF 379 LTRAKFEEL L T P+ V++++ +K +I+EI+LVGGSTR+P +Q+LV+ Sbjct: 278 LKLTRAKFEELTKPLLERTRNPISDVIKEAKIKPEEINEILLVGGSTRMPAVQKLVESMV 337 Query: 380 NGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPR 439 GK+P+R INPDE VA GAA+Q GVL G D D++LLDV PLTL IET+GGV T LI R Sbjct: 338 PGKKPNRSINPDEVVAIGAAIQGGVLRG--DVKDVLLLDVTPLTLSIETLGGVATPLIKR 395 Query: 440 NTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEV 499 NT +P KSQIFSTA DNQ +V + V +GERP+++DN LG F+L GI PAP+G PQIE+ Sbjct: 396 NTTIPVSKSQIFSTAQDNQESVDVVVCQGERPMSRDNKSLGRFNLGGIQPAPKGKPQIEI 455 Query: 500 TFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERI 559 TF +D NGIL V A+D T +N ITI+++ N L+ EEI++M+ DAE E D ++ERI Sbjct: 456 TFSLDANGILNVKAKDLTTQKENSITISDNGN-LSEEEIQKMIRDAEANKERDNIIRERI 514 Query: 560 DTRNELE 566 + RNE E Sbjct: 515 ELRNEGE 521 >2QXL-A nrPDB Length = 658 Score = 241 bits (615), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 182/635 (28%), Positives = 303/635 (47%), Gaps = 56/635 (8%) Query: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 T G+DLG S + V +N ++I+ N+ NR TPS V F P+ R +G+ KN+ TSN Sbjct: 1 STPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKN-RYLGETGKNKQTSN 59 Query: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVE---KKTKPYIQVDIGGGQTKTFAPEE 144 +NTV + KR+IG ++ P +Q+ K K+VE KKT ++ G+ F+ + Sbjct: 60 IKNTVANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRF---AGEKHVFSATQ 116 Query: 145 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA 204 ++AM + K+K+T + +T + VP ++ + QR DA IAGLN +RI+N+ TA Sbjct: 117 LAAMFIDKVKDTVKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTA 176 Query: 205 AAIAYGL---DKREGEK--NILVF-DLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDF 258 A ++YG+ D EGE+ I+ F D+G ++ S++ G +V+ T D H GG DF Sbjct: 177 AGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDF 236 Query: 259 DQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDF 318 D + EHF +K K D+R++ +A ++ EK K+ LS+ A +ES D Sbjct: 237 DLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDV 296 Query: 319 SETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEF 378 S L+R + EEL L +PV K L + L ++D + ++GG+TRIP ++Q + E Sbjct: 297 SSQLSREELEELVKPLLERVTEPVTKALAQAKLSAEEVDFVEIIGGTTRIPTLKQSISEA 356 Query: 379 FNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGV----MT 434 F GK S +N DEA+A GAA + S D+ P ++ V Sbjct: 357 F-GKPLSTTLNQDEAIAKGAAFICAIHSPTLRVRPFKFEDIHPYSVSYSWDKQVEDEDHM 415 Query: 435 KLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGI--PPAPR 492 ++ P + P+ K + D + P T + + +++TG+ P Sbjct: 416 EVFPAGSSFPSTKLITLNRTGDFSMAASYTDITQLPPNTPEQ--IANWEITGVQLPEGQD 473 Query: 493 GVPQIEVTFEIDVNGILRV----TAED------------------------KGTGNKNKI 524 VP +++ D +G+ + T ED T K+ + Sbjct: 474 SVP-VKLKLRCDPSGLHTIEEAYTIEDIEVEEPIPLPEDAPEDAEQEFKKVTKTVKKDDL 532 Query: 525 TITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGG 584 TI L +++ ++ + +DK + E D +N LE Y Y+L+ ++ +E+ Sbjct: 533 TIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETEDRKNTLEEYIYTLRGKL--EEEYAP 590 Query: 585 KLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAK 619 S +K ++ + + EWL D + KAK Sbjct: 591 FASDAEKTKLQGMLNKAEEWL---YDEGFDSIKAK 622 >5MB9-A nrPDB Length = 590 Score = 187 bits (474), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 128/399 (32%), Positives = 209/399 (52%), Gaps = 35/399 (8%) Query: 30 VVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPE 89 V+GI G + S + + + E+IAN+ G+R P+ +++ +G+ G AKN L NP+ Sbjct: 27 VIGITFGNSNSSIAHTVDDKAEVIANEDGDRQIPTILSYV-DGDEYYGQQAKNFLVRNPK 85 Query: 90 NTVFDAKRLIGR-------TWNDPSV--QQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTF 140 NTV + ++G+ T N S Q+ + F + +K + + T Sbjct: 86 NTVAYFRDILGQDFKSVDPTHNHASAHPQEAGDNVVFTIKDKAEE--------DAEPSTL 137 Query: 141 APEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIIN 200 EI+ L ++ A YLGKKVT AV+T+P F + Q+ A A A L V+++I+ Sbjct: 138 TVSEIATRYLRRLVGAASEYLGKKVTSAVITIPTNFTEKQKAALIAAAAAADLEVLQLIS 197 Query: 201 EPTAAAIAYGLDKRE----GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256 EP AA +AY D R +K I+V DLGG DV++L +G++ ++AT D G Sbjct: 198 EPAAAVLAY--DARPEATISDKIIVVADLGGSRSDVTVLASRSGMYTILATVHDYEYHGI 255 Query: 257 DFDQRVMEHFIKLYKKKT--GKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFE 314 D+ +++HF K + KK KD R++ R++ KLR E E KRALS A +ES + Sbjct: 256 ALDKVLIDHFSKEFLKKNPGAKDPRENPRSLAKLRLEAESTKRALSRSTNASFSVESLID 315 Query: 315 GEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQL 374 G DF+ T+ R ++E + +F + V+ ++ + L D+DE+++ GG++ P+I Sbjct: 316 GLDFASTINRLRYETIARTVFEGFNRLVESAVKKAGLDPLDVDEVIMSGGTSNTPRIAAN 375 Query: 375 VKEFF--------NGKEPSRGINPDEAVAYGAAVQAGVL 405 + F +PS +NP E A GAA+QA ++ Sbjct: 376 FRYIFPESTRILAPSTDPS-ALNPSELQARGAALQASLI 413 >1JCE-A nrPDB Length = 344 Score = 62.4 bits (150), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 92/379 (24%), Positives = 162/379 (42%), Gaps = 72/379 (18%) Query: 31 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90 +GIDLGT + V F G+ I+ N+ PS +A + T Sbjct: 6 IGIDLGTANTLV--FLRGK-GIVVNE------PSVIAI-------------DSTTGEILK 43 Query: 91 TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150 +AK +IG+T P+ + I+ + V+ T + + + F + M L Sbjct: 44 VGLEAKNMIGKT---PATIKAIRPMRDGVIADYTVALVML-------RYFINKAKGGMNL 93 Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210 K V+ VP D +R+A DAG AG + + +I EP AAAI Sbjct: 94 FK-------------PRVVIGVPIGITDVERRAILDAGLEAGASKVFLIEEPMAAAIGSN 140 Query: 211 LDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLY 270 L+ E N +V D+GGGT +V+++++ + + T + G++ D+ ++++ + Y Sbjct: 141 LNVEEPSGN-MVVDIGGGTTEVAVISLGS-----IVTWESIRIAGDEMDEAIVQYVRETY 194 Query: 271 KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTR------ 324 + G+ R ++++ E+ S+ E+E+ G D S L R Sbjct: 195 RVAIGE------RTAERVKIEI---GNVFPSKEND--ELETTVSGIDLSTGLPRKLTLKG 243 Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLK-KSDIDE--IVLVGGSTRIPKIQQLVKEFFNG 381 + E + + ++ V+ LE + + SDI E I L GG + + + L+++ G Sbjct: 244 GEVREALRSVVVAIVESVRTTLEKTPPELVSDIIERGIFLTGGGSLLRGLDTLLQK-ETG 302 Query: 382 KEPSRGINPDEAVAYGAAV 400 R P AVA GA + Sbjct: 303 ISVIRSEEPLTAVAKGAGM 321 >4CZI-A nrPDB Length = 348 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 33/128 (25%), Positives = 67/128 (52%), Gaps = 12/128 (9%) Query: 169 VVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGG 228 +V VP+ +R+A D+ AG + +I+EP AAAI GL E + +V D+GGG Sbjct: 101 IVCVPSGATAVERRAINDSCLNAGARRVGLIDEPMAAAIGAGLPIHEPTGS-MVVDIGGG 159 Query: 229 TFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKL 288 T +V++L++ V+ + +GG+ D+ ++ + + + G+ +++ Sbjct: 160 TTEVAVLSLSGIVY-----SRSVRVGGDKMDEAIISYMRRHHNLLIGETT------AERI 208 Query: 289 RREVEKAK 296 ++E+ A+ Sbjct: 209 KKEIGTAR 216 >3H1Q-A nrPDB Length = 272 Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 14/109 (12%) Query: 149 VLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIA 208 ++ ++K E LG ++ A +P +A AGL ++ +++EP AAA A Sbjct: 76 IVRELKAKVERLLGSELFQAATAIPPGTVGRNAEACGHVVAGAGLELVTLVDEPVAAARA 135 Query: 209 YGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVAT----NGDTHL 253 G++ +V D+GGGT +++ I+ G ++ AT G THL Sbjct: 136 LGINDG------IVVDIGGGTTGIAV--IEKG--KITATFDEPTGGTHL 174 >5EOY-A nrPDB Length = 357 Score = 33.1 bits (74), Expect = 0.42, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 6/71 (8%) Query: 354 SDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGD 413 +D+D IVL GG+ I + +L+++ P+ NP +A V AG L+ D Sbjct: 289 NDVDYIVLAGGTASIQDLDRLIQQKIG--TPTLVANPFADMALNGKVNAGALASDAPA-- 344 Query: 414 LVLLDVCPLTL 424 L+ C L L Sbjct: 345 --LMIACGLAL 353 >4TU3-X nrPDB Length = 623 Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 8/83 (9%) Query: 549 AEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESH 608 AE K L+ + SY Y L N + EK+G S K +E+ W + Sbjct: 109 AEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAAS-------WKTADERFFW-NHY 160 Query: 609 QDADIEDFKAKKKELEEIVQPII 631 D+ +F + ++ +QP+I Sbjct: 161 LTEDLRNFAHQDPRIDSFIQPVI 183 >1NBW-A nrPDB Length = 607 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 53/212 (25%), Positives = 91/212 (42%), Gaps = 29/212 (13%) Query: 206 AIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEV-VATNGD-------THLGGED 257 AIA L + + DLG G+ D +++ + + V +A G+ T LG ED Sbjct: 397 AIAGALTTPGCAAPLAILDLGAGSTDAAIVNAEGQITAVHLAGAGNMVSLLIKTELGLED 456 Query: 258 FDQRVMEHFIKLY---KKKTGKDVRKDNRAVQKLRREVEKA--KRALSSQHQARIEIESF 312 + IK Y K ++ +R +N AV+ R + A + + + + I++ Sbjct: 457 LS---LAEAIKKYPLAKVESLFSIRHENGAVEFFREALSPAVFAKVVYIKEGELVPIDNA 513 Query: 313 FEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQ 372 E +AK + + R+ +++V ++ DI +VLVGGS+ +I Sbjct: 514 SPLEKIRLVRRQAKEKVFVTNCLRA----LRQVSPGGSIR--DIAFVVLVGGSSLDFEIP 567 Query: 373 QLVKEFFN------GKEPSRGI-NPDEAVAYG 397 QL+ E + G+ RG P AVA G Sbjct: 568 QLITEALSHYGVVAGQGNIRGTEGPRNAVATG 599 >3LWT-X nrPDB Length = 505 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 9/88 (10%) Query: 544 DAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIE 603 D+E+ AE K L+ + SY Y L N + EK+G S K +E+ Sbjct: 106 DSEE-AEYIKLLELHLKNSTFYFSYTYDLTNSLQRNEKVGPAAS-------WKTADERFF 157 Query: 604 WLESHQDADIEDFKAKKKELEEIVQPII 631 W + D+ +F + ++ +QP+I Sbjct: 158 W-NHYLTEDLRNFAHQDPRIDSFIQPVI 184 >6IRV-A nrPDB Length = 508 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 23/124 (18%) Query: 515 DKGTGNKNKITITNDQNRLTPEEIERMVNDAE------KFAEEDKKLKERIDTRNELESY 568 DKG+ + + +N + ++P ++ND KF EE K+L L Y Sbjct: 80 DKGS---DPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRL---------LFKY 127 Query: 569 AYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQ 628 A + + I + SP+ ++ ++ VE+ WL A ED+ + + L Sbjct: 128 AEAARRLIESRSA-----SPDSRKVVKWNVEDTFSWLRKDHSASKEDYMDRLEHLRRQCG 182 Query: 629 PIIS 632 P +S Sbjct: 183 PHVS 186 >5LJV-A nrPDB Length = 347 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 9/93 (9%) Query: 144 EISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQAT-KDAGTIAGLNVMRIINEP 202 E++ +LT + ++AE ++ AV+ VPA + A + K A + ++ +++EP Sbjct: 88 EVARHLLTHVVKSAEPGPNDEIC-AVIGVPARASAANKALLLKMAQEV--VHTALVVSEP 144 Query: 203 TAAAIAYGLDKREGEKNILVFDLGGGTFDVSLL 235 + YGLDK N ++ D+G GT D+ L Sbjct: 145 FM--VGYGLDKL---INTIIVDIGAGTTDICAL 172 >2G3M-A nrPDB Length = 693 Score = 30.8 bits (68), Expect = 2.2, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 126 PYIQVDIGGGQTKTFAPEEISAMVLTKMKETA---EAYLGKKVTHAVVTVPAYFNDAQRQ 182 P++ DIGG Q + FA + S +L K A Y K T + T P + D ++ Sbjct: 440 PFVGCDIGGFQGRNFAEIDNSMDLLVKYYALALFFPFYRSHKATDGIDTEPVFLPDYYKE 499 Query: 183 ATKD 186 K+ Sbjct: 500 KVKE 503 >5SVC-B nrPDB Length = 727 Score = 30.0 bits (66), Expect = 3.4, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 198 IINEPTAAAI-AYGLDKREGEKNILVFDLGGGTFDVSLLT 236 I++ P I A L + G KNI D+GG +FDV+L+T Sbjct: 292 IVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALIT 331 >6IRX-A nrPDB Length = 496 Score = 29.6 bits (65), Expect = 3.9, Method: Compositional matrix adjust. Identities = 24/108 (22%), Positives = 47/108 (43%), Gaps = 20/108 (18%) Query: 533 LTPEEIERMVNDAE------KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKL 586 ++P ++ND K+ EE +KL L YA + K I + + Sbjct: 86 ISPSMFREIMNDIPIRLSRIKYKEEARKL---------LFKYAEAAKKMIDSR-----NV 131 Query: 587 SPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKL 634 +PE ++ ++ VE+ + WL A ED+ + + L + P ++ + Sbjct: 132 TPESRKVVKWNVEDTMNWLRRDHSASKEDYMDRLENLRKQCGPHVASV 179 >1H1Z-A nrPDB Length = 228 Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust. Identities = 39/160 (24%), Positives = 64/160 (40%), Gaps = 20/160 (12%) Query: 127 YIQVDIGGGQTKTFAPE-EISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATK 185 ++ +DI G F P I A V+ +++ +AYL H +VT P+ + + +A Sbjct: 35 WLHMDIMDGH---FVPNLTIGAPVIQSLRKHTKAYLD---CHLMVTNPSDYVEPLAKAGA 88 Query: 186 DAGT----IAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGV 241 T ++ N +I A + G+ R G VF L+ +N V Sbjct: 89 SGFTFHIEVSRDNWQELIQSIKAKGMRPGVSLRPGTPVEEVF---------PLVEAENPV 139 Query: 242 FEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKD 281 V+ + GG+ F +ME L KK D+ D Sbjct: 140 ELVLVMTVEPGFGGQKFMPEMMEKVRALRKKYPSLDIEVD 179 >3IA5-A nrPDB Length = 162 Score = 29.3 bits (64), Expect = 6.4, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 13/91 (14%) Query: 281 DNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRST-M 339 DN+ L E++ KRA + G + E++ R LN+ L R T Sbjct: 18 DNKMPWHLPAELQLFKRATLGK--------PIVMGRNTFESIGRPLPGRLNIVLSRQTDY 69 Query: 340 KP----VQKVLEDSDLKKSDIDEIVLVGGST 366 +P V LED+ + D++E++++GG+T Sbjct: 70 QPEGVTVVATLEDAVVAAGDVEELMIIGGAT 100 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5E84-A nrPDB 856 0.0 5FPN-A nrPDB 807 0.0 5TKY-A nrPDB 700 0.0 4JN4-A nrPDB 693 0.0 4RTF-D nrPDB 647 0.0 4ANI-C nrPDB 641 0.0 5OBV-A nrPDB 619 e-178 2QXL-A nrPDB 598 e-171 5MB9-A nrPDB 347 7e-96 1JCE-A nrPDB 250 2e-66 4CZI-A nrPDB 184 8e-47 Sequences not found previously or not previously below threshold: 3H1Q-A nrPDB 64 3e-10 5LJV-A nrPDB 52 6e-07 2YCH-A nrPDB 46 7e-05 3I8B-A nrPDB 41 0.002 2D0P-A nrPDB 37 0.027 5EOY-A nrPDB 37 0.030 3JAX-A nrPDB 35 0.096 1NBW-A nrPDB 35 0.098 3J9V-F nrPDB 34 0.20 1C0F-A nrPDB 33 0.45 4ZXZ-A nrPDB 33 0.51 5MLC-9 nrPDB 32 0.65 5NKS-A nrPDB 32 0.69 4B3J-A nrPDB 32 0.72 6IRV-A nrPDB 32 0.92 6IRX-A nrPDB 31 1.7 4N44-A nrPDB 31 1.8 4ISJ-A nrPDB 31 2.1 5SVC-B nrPDB 31 2.2 3B2Q-A nrPDB 30 3.3 1E4F-T nrPDB 30 3.8 2DKH-A nrPDB 30 4.0 1F1M-A nrPDB 29 6.2 >5E84-A nrPDB Length = 606 Score = 856 bits (2212), Expect = 0.0, Method: Composition-based stats. Identities = 599/609 (98%), Positives = 600/609 (98%), Gaps = 4/609 (0%) Query: 25 EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL 84 EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL Sbjct: 2 EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL 61 Query: 85 TSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEE 144 TSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEE Sbjct: 62 TSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEE 121 Query: 145 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA 204 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA Sbjct: 122 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA 181 Query: 205 AAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 264 AAIAYGLDKREGEKNILVFDLGGG FDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME Sbjct: 182 AAIAYGLDKREGEKNILVFDLGGGAFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 241 Query: 265 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTR 324 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESF+EGEDFSETLTR Sbjct: 242 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTR 301 Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 384 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP Sbjct: 302 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 361 Query: 385 SRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444 SRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP Sbjct: 362 SRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 421 Query: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504 TKKSQIFS TVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID Sbjct: 422 TKKSQIFSVGG----TVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 477 Query: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE Sbjct: 478 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 537 Query: 565 LESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 624 LESYAYSLKNQIGDKEKLGGKLS EDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE Sbjct: 538 LESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 597 Query: 625 EIVQPIISK 633 EIVQPIISK Sbjct: 598 EIVQPIISK 606 >5FPN-A nrPDB Length = 640 Score = 807 bits (2083), Expect = 0.0, Method: Composition-based stats. Identities = 397/613 (64%), Positives = 494/613 (80%), Gaps = 8/613 (1%) Query: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 G +GIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+ N Sbjct: 6 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 64 Query: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147 P NT+FDAKRLIGR + D +VQ D+K PF+VV + KP +QV+ G+TKTF PEEIS+ Sbjct: 65 PTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYK-GETKTFFPEEISS 123 Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207 MVLTKMKE AEAYLG KV AV+TVPAYFND+QRQATKDAGTI GLNV+RIINEPTAAAI Sbjct: 124 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 183 Query: 208 AYGLDKRE---GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVME 264 AYGLDK+ GEKN+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ Sbjct: 184 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 243 Query: 265 HFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTR 324 H + +K+K KD+ + RAV++LR E+AKR LSS QA IEI+S +EG DF ++TR Sbjct: 244 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 303 Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 384 A+FEELN DLFR T++PV+K L D+ L K I EIVLVGGSTRIPKIQ+L+++FFNGKE Sbjct: 304 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 363 Query: 385 SRGINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTV 442 ++ INPDEAVAYGAAVQA +L GD ++ DL+LLDV PL+LGIET GGVMT LI RNT Sbjct: 364 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 423 Query: 443 VPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFE 502 +PTK++Q F+T SDNQ +V ++VYEGER +TKDN+LLG FDLTGIPPAPRGVPQIEVTF+ Sbjct: 424 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFD 483 Query: 503 IDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTR 562 ID NGIL VTA DK TG +NKITITND+ RL+ ++I+RMV +AE++ ED+ ++R+ + Sbjct: 484 IDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAK 543 Query: 563 NELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKE 622 N LESY Y++K + D EKL GK+S +DK + +E I WL+ +Q A+ ++++ K+KE Sbjct: 544 NALESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKE 602 Query: 623 LEEIVQPIISKLY 635 LE + PIISKLY Sbjct: 603 LERVCNPIISKLY 615 >5TKY-A nrPDB Length = 621 Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats. Identities = 333/608 (54%), Positives = 436/608 (71%), Gaps = 9/608 (1%) Query: 30 VVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPE 89 +GIDLGTTYSCV V++ VEIIAN+QGN TPS+V+FT E RLIG+AAKNQ NP Sbjct: 16 AIGIDLGTTYSCVAVYEGTNVEIIANEQGNFTTPSFVSFT-ENCRLIGEAAKNQAAMNPA 74 Query: 90 NTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMV 149 NT+FD KRLIGR ++DP+V++D++ PFKVV+ P ++V GQT TF+P+EISAMV Sbjct: 75 NTIFDVKRLIGRRFDDPTVKKDMESWPFKVVDDNGNPKVEVQYL-GQTHTFSPQEISAMV 133 Query: 150 LTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAY 209 LTKMKE AE LGKKV AV+TVPAYFND QRQATKDAG IAGLNV+RIINEPTAAAIAY Sbjct: 134 LTKMKEIAETKLGKKVEKAVITVPAYFNDNQRQATKDAGAIAGLNVLRIINEPTAAAIAY 193 Query: 210 GLD--KREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFI 267 GL K + E+N+L++DLGGG FDVSLL I GVF V AT GDTHLGG+DFD ++E+ Sbjct: 194 GLGSGKSDKERNVLIYDLGGGAFDVSLLNIQGGVFTVKATAGDTHLGGQDFDTNLLEYCK 253 Query: 268 KLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKF 327 K + +KT KD+ D RA+++LR E+AKR LSS Q IEI+S F+GEDF+ +TRA+F Sbjct: 254 KEFTRKTKKDLSGDARALRRLRTACERAKRTLSSGAQTTIEIDSLFDGEDFNIQITRARF 313 Query: 328 EELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRG 387 E+LN F T++PV +VL+D+ ++K +DEIVLVGGSTRIP+IQ+L+ EFF+GK+ + Sbjct: 314 EDLNAKAFAGTLEPVAQVLKDAGIEKHQVDEIVLVGGSTRIPRIQKLLSEFFDGKKLEKS 373 Query: 388 INPDEAVAYGAAVQAGVLSG---DQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444 INPDEAVAYGAAVQAG+LSG DT DL+LLDV PL+LG+ G + ++PR VP Sbjct: 374 INPDEAVAYGAAVQAGILSGKATSADTSDLLLLDVVPLSLGVAMEGNIFAPVVPRGQTVP 433 Query: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504 T K + F+T +DNQ TV VY+GER +DN LLG F L IPP G P +EV FE+D Sbjct: 434 TIKKRTFTTVADNQQTVQFPVYQGERVNCEDNTLLGEFTLAPIPPMKAGEPVLEVVFEVD 493 Query: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564 VNGIL+VTA +K +G ITI N +L+ +EIE+M++DAEKF + + +R + + + Sbjct: 494 VNGILKVTATEKTSGRSANITIANSVGKLSTDEIEKMISDAEKFKSKCEAFSKRFEAKQQ 553 Query: 565 LESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELE 624 LESY ++ I D L KL K+ +E+A+ E + LE +D+ ++ K K+ L+ Sbjct: 554 LESYISRVEEIISDP-TLSLKLKRGQKDKIEQALSEAMAQLE-IEDSTADELKKKELALK 611 Query: 625 EIVQPIIS 632 +V ++ Sbjct: 612 RLVTKAMA 619 >4JN4-A nrPDB Length = 608 Score = 693 bits (1787), Expect = 0.0, Method: Composition-based stats. Identities = 304/613 (49%), Positives = 408/613 (66%), Gaps = 28/613 (4%) Query: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 G ++GIDLGTT SCV + ++ N +G+R TPS +A+T +GE L+G AK Q +N Sbjct: 2 GKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTN 61 Query: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVE-KKTKPYIQVDIGGGQTKTFAPEEIS 146 P+NT+F KRLIGR + D VQ+D+ +PFK++ +++V + + AP +IS Sbjct: 62 PQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEV-----KGQKMAPPQIS 116 Query: 147 AMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAA 206 A VL KMK+TAE YLG+ VT AV+TVPAYFNDAQRQATKDAG IAGL V RIINEPTAAA Sbjct: 117 AEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAA 176 Query: 207 IAYGLDKREGEKNILVFDLGGGTFDVSLLTI----DNGVFEVVATNGDTHLGGEDFDQRV 262 +AYGLDK G + I V+DLGGG FD+S++ I FEV+ATNGDTHLGGEDFD R+ Sbjct: 177 LAYGLDKGTGNRTIAVYDLGGGAFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236 Query: 263 MEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEG----EDF 318 + + ++ +KK G D+R D A+Q+L+ EKAK LSS Q + + + Sbjct: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHM 296 Query: 319 SETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEF 378 + +TRAK E L DL +++P++ L+D+ L SDID+++LVGG TR+P +Q+ V EF Sbjct: 297 NIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEF 356 Query: 379 FNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIP 438 F GKEP + +NPDEAVA GAAVQ GVL+G D D++LLDV PL+LGIET+GGVMT LI Sbjct: 357 F-GKEPRKDVNPDEAVAIGAAVQGGVLTG--DVKDVLLLDVTPLSLGIETMGGVMTTLIA 413 Query: 439 RNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIE 498 +NT +PTK SQ+FS VTI V +GER DN LG F+L GI PAPRG+PQIE Sbjct: 414 KNTTIPTKHSQVFSMGG----AVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIE 469 Query: 499 VTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKER 558 VTF+ID +GIL V+A+DK +G + KITI L +EI++MV DAE AE D+K +E Sbjct: 470 VTFDIDADGILHVSAKDKNSGKEQKITIKASSG-LNEDEIQKMVRDAEANAEADRKFEEL 528 Query: 559 IDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKA 618 + TRN+ + +S + Q+ E+ G KL +DK +E A+ L+ A IE A Sbjct: 529 VQTRNQGDHLLHSTRKQV---EEAGDKLPADDKTAIESALTALETALKGEDKAAIE---A 582 Query: 619 KKKELEEIVQPII 631 K +EL ++ Q ++ Sbjct: 583 KMQELAQVSQKLM 595 >4RTF-D nrPDB Length = 546 Score = 647 bits (1669), Expect = 0.0, Method: Composition-based stats. Identities = 294/542 (54%), Positives = 371/542 (68%), Gaps = 36/542 (6%) Query: 30 VVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPE 89 VGIDLGTT S V V + G ++AN +G+R TPS VAF GE L+G AKNQ +N + Sbjct: 36 AVGIDLGTTNSVVSVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVTNVD 95 Query: 90 NTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMV 149 TV KR +G W+ I++D K + EISA + Sbjct: 96 RTVRSVKRHMGSDWS-----------------------IEID-----GKKYTAPEISARI 127 Query: 150 LTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAY 209 L K+K AEAYLG+ +T AV+T PAYFNDAQRQATKDAG IAGLNV+RI+NEPTAAA+AY Sbjct: 128 LMKLKRDAEAYLGEDITDAVITTPAYFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAY 187 Query: 210 GLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKL 269 GLDK E E+ ILVFDLGGGTFDVSLL I GV EV AT+GD HLGG+D+DQRV++ + Sbjct: 188 GLDKGEKEQRILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDQRVVDWLVDK 247 Query: 270 YKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGED-----FSETLTR 324 +K +G D+ KD A+Q+LR EKAK LSS I + D E LTR Sbjct: 248 FKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTR 307 Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEP 384 A+F+ + DL T KP Q V+ D+ + S+ID +VLVGGSTR+P + LVKE GKEP Sbjct: 308 AEFQRITQDLLDRTRKPFQSVIADTGISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKEP 367 Query: 385 SRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444 ++G+NPDE VA GAA+QAGVL G + D++LLDV PL+LGIET GGVMT+LI RNT +P Sbjct: 368 NKGVNPDEVVAVGAALQAGVLKG--EVKDVLLLDVTPLSLGIETKGGVMTRLIERNTTIP 425 Query: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEID 504 TK+S+ F+TA DNQP+V I+VY+GER + N LLG+F+LTGIPPAPRG+PQIEVTF+ID Sbjct: 426 TKRSETFTTADDNQPSVQIQVYQGEREIAAHNKLLGSFELTGIPPAPRGIPQIEVTFDID 485 Query: 505 VNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNE 564 NGI+ VTA+DKGTG +N I I + + L+ E+I+RM+ DAE AEED+K +E D RN+ Sbjct: 486 ANGIVHVTAKDKGTGKENTIRI-QEGSGLSKEDIDRMIKDAEAHAEEDRKRREEADVRNQ 544 Query: 565 LE 566 E Sbjct: 545 AE 546 >4ANI-C nrPDB Length = 509 Score = 641 bits (1652), Expect = 0.0, Method: Composition-based stats. Identities = 289/543 (53%), Positives = 376/543 (69%), Gaps = 39/543 (7%) Query: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 ++GIDLGTT SCV V + G V++I N +GNR TPS VAF GERL+G+ AK Q +N Sbjct: 2 SKIIGIDLGTTNSCVAVLEGGEVKVIPNPEGNRTTPSVVAFK-NGERLVGEVAKRQAITN 60 Query: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147 P NT+ KR +G + +++ + K + P+EISA Sbjct: 61 P-NTIISIKRHMGTDY-----------------------KVEI-----EGKQYTPQEISA 91 Query: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207 ++L +K AE YLG+ VT AV+TVPAYFNDAQRQATKDAG IAGL V RIINEPTAAA+ Sbjct: 92 IILQYLKSYAEDYLGEPVTRAVITVPAYFNDAQRQATKDAGRIAGLEVERIINEPTAAAL 151 Query: 208 AYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFI 267 AYGLDK E ++ ILV+DLGGGTFDVS+L + +GVFEV AT GD HLGG+DFDQ ++++ + Sbjct: 152 AYGLDKEE-DQTILVYDLGGGTFDVSILELGDGVFEVKATAGDNHLGGDDFDQVIIDYLV 210 Query: 268 KLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGED----FSETLT 323 +K++ G D+ KD A+Q+L+ EKAK+ LS Q +I + E+ TLT Sbjct: 211 NQFKQEHGIDLSKDKMALQRLKDAAEKAKKELSGVTQTQISLPFISANENGPLHLEMTLT 270 Query: 324 RAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKE 383 RAKFEEL+ L TM PV++ L+D+ L +DID+++LVGGSTRIP +Q+ +K GKE Sbjct: 271 RAKFEELSAHLVERTMGPVRQALQDAGLTPADIDKVILVGGSTRIPAVQEAIKREL-GKE 329 Query: 384 PSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVV 443 P +G+NPDE VA GAA+Q GV++G + D+VLLDV PL+LGIET+GGV TKLI RNT + Sbjct: 330 PHKGVNPDEVVAIGAAIQGGVIAG--EVKDVVLLDVTPLSLGIETMGGVFTKLIERNTTI 387 Query: 444 PTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEI 503 PT KSQ+F+TA+DNQ TV I V +GERP+ DN LG F LTGIPPAPRGVPQIEVTF+I Sbjct: 388 PTSKSQVFTTAADNQTTVDIHVLQGERPMAADNKSLGRFQLTGIPPAPRGVPQIEVTFDI 447 Query: 504 DVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRN 563 D NGI+ V A+D GT + ITI + L+ EEI+RM+ +AE+ AE D+K KE + RN Sbjct: 448 DANGIVHVRAKDLGTNKEQSITIKSSSG-LSEEEIQRMIKEAEENAEADRKRKEAAELRN 506 Query: 564 ELE 566 E + Sbjct: 507 EAD 509 >5OBV-A nrPDB Length = 529 Score = 619 bits (1597), Expect = e-178, Method: Composition-based stats. Identities = 271/546 (49%), Positives = 363/546 (66%), Gaps = 33/546 (6%) Query: 26 DVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLT 85 D G ++GIDLGTT SCV V + GR ++ N +G R TPS V++ E ++GDAAK Q+ Sbjct: 4 DNGLIIGIDLGTTNSCVSVMEGGRPVVLENPEGKRTTPSIVSYK-NNEIIVGDAAKRQMV 62 Query: 86 SNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEI 145 +NP NT+ KRL+G T ++V G TK +PE++ Sbjct: 63 TNP-NTIVSIKRLMG-----------------------TSNKVKVQNADGTTKELSPEQV 98 Query: 146 SAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAA 205 SA +L+ +K+ AE +GKK++ AV+TVPAYFNDA+R ATK AG IAGLNV RIINEPTAA Sbjct: 99 SAQILSYLKDFAEKKIGKKISRAVITVPAYFNDAERNATKTAGKIAGLNVERIINEPTAA 158 Query: 206 AIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEH 265 A+AYG+DK E +LV+DLGGGTFDVSLL I G FEV+AT GD LGG+D+D +++E+ Sbjct: 159 ALAYGIDKASREMKVLVYDLGGGTFDVSLLDIAEGTFEVLATAGDNRLGGDDWDNKIIEY 218 Query: 266 FIKLY-KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEG----EDFSE 320 K+ G ++ KD A+Q+L+ E+AK LS+Q + I + + Sbjct: 219 ISAYIAKEHQGLNLSKDKMAMQRLKEAAERAKIELSAQLETIISLPFLTVTQKGPVNVEL 278 Query: 321 TLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFN 380 LTRAKFEEL L T P+ V++++ +K +I+EI+LVGGSTR+P +Q+LV+ Sbjct: 279 KLTRAKFEELTKPLLERTRNPISDVIKEAKIKPEEINEILLVGGSTRMPAVQKLVESMVP 338 Query: 381 GKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRN 440 GK+P+R INPDE VA GAA+Q GVL G D D++LLDV PLTL IET+GGV T LI RN Sbjct: 339 GKKPNRSINPDEVVAIGAAIQGGVLRG--DVKDVLLLDVTPLTLSIETLGGVATPLIKRN 396 Query: 441 TVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVT 500 T +P KSQIFSTA DNQ +V + V +GERP+++DN LG F+L GI PAP+G PQIE+T Sbjct: 397 TTIPVSKSQIFSTAQDNQESVDVVVCQGERPMSRDNKSLGRFNLGGIQPAPKGKPQIEIT 456 Query: 501 FEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERID 560 F +D NGIL V A+D T +N ITI+++ N L+ EEI++M+ DAE E D ++ERI+ Sbjct: 457 FSLDANGILNVKAKDLTTQKENSITISDNGN-LSEEEIQKMIRDAEANKERDNIIRERIE 515 Query: 561 TRNELE 566 RNE E Sbjct: 516 LRNEGE 521 >2QXL-A nrPDB Length = 658 Score = 598 bits (1541), Expect = e-171, Method: Composition-based stats. Identities = 179/635 (28%), Positives = 301/635 (47%), Gaps = 56/635 (8%) Query: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 T G+DLG S + V +N ++I+ N+ NR TPS V F P+ R +G+ KN+ TSN Sbjct: 1 STPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKN-RYLGETGKNKQTSN 59 Query: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV---EKKTKPYIQVDIGGGQTKTFAPEE 144 +NTV + KR+IG ++ P +Q+ K K+V +KKT ++ G+ F+ + Sbjct: 60 IKNTVANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRF---AGEKHVFSATQ 116 Query: 145 ISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTA 204 ++AM + K+K+T + +T + VP ++ + QR DA IAGLN +RI+N+ TA Sbjct: 117 LAAMFIDKVKDTVKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTA 176 Query: 205 AAIAYGL---DKREGEKN---ILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDF 258 A ++YG+ D EGE+ + D+G ++ S++ G +V+ T D H GG DF Sbjct: 177 AGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDF 236 Query: 259 DQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDF 318 D + EHF +K K D+R++ +A ++ EK K+ LS+ A +ES D Sbjct: 237 DLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDV 296 Query: 319 SETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEF 378 S L+R + EEL L +PV K L + L ++D + ++GG+TRIP ++Q + E Sbjct: 297 SSQLSREELEELVKPLLERVTEPVTKALAQAKLSAEEVDFVEIIGGTTRIPTLKQSISEA 356 Query: 379 FNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGV----MT 434 F GK S +N DEA+A GAA + S D+ P ++ V Sbjct: 357 F-GKPLSTTLNQDEAIAKGAAFICAIHSPTLRVRPFKFEDIHPYSVSYSWDKQVEDEDHM 415 Query: 435 KLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGI--PPAPR 492 ++ P + P+ K + D + P T + + +++TG+ P Sbjct: 416 EVFPAGSSFPSTKLITLNRTGDFSMAASYTDITQLPPNTPEQ--IANWEITGVQLPEGQD 473 Query: 493 GVPQIEVTFEIDVNGILRV----TAED------------------------KGTGNKNKI 524 VP +++ D +G+ + T ED T K+ + Sbjct: 474 SVP-VKLKLRCDPSGLHTIEEAYTIEDIEVEEPIPLPEDAPEDAEQEFKKVTKTVKKDDL 532 Query: 525 TITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGG 584 TI L +++ ++ + +DK + E D +N LE Y Y+L+ ++ +E+ Sbjct: 533 TIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETEDRKNTLEEYIYTLRGKL--EEEYAP 590 Query: 585 KLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAK 619 S +K ++ + + EWL D + KAK Sbjct: 591 FASDAEKTKLQGMLNKAEEWL---YDEGFDSIKAK 622 >5MB9-A nrPDB Length = 590 Score = 347 bits (891), Expect = 7e-96, Method: Composition-based stats. Identities = 127/399 (31%), Positives = 209/399 (52%), Gaps = 35/399 (8%) Query: 30 VVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPE 89 V+GI G + S + + + E+IAN+ G+R P+ +++ +G+ G AKN L NP+ Sbjct: 27 VIGITFGNSNSSIAHTVDDKAEVIANEDGDRQIPTILSYV-DGDEYYGQQAKNFLVRNPK 85 Query: 90 NTVFDAKRLIGRTW-------NDPSV--QQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTF 140 NTV + ++G+ + N S Q+ + F + +K + + T Sbjct: 86 NTVAYFRDILGQDFKSVDPTHNHASAHPQEAGDNVVFTIKDKAEE--------DAEPSTL 137 Query: 141 APEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIIN 200 EI+ L ++ A YLGKKVT AV+T+P F + Q+ A A A L V+++I+ Sbjct: 138 TVSEIATRYLRRLVGAASEYLGKKVTSAVITIPTNFTEKQKAALIAAAAAADLEVLQLIS 197 Query: 201 EPTAAAIAYGLDKRE----GEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256 EP AA +AY D R +K I+V DLGG DV++L +G++ ++AT D G Sbjct: 198 EPAAAVLAY--DARPEATISDKIIVVADLGGSRSDVTVLASRSGMYTILATVHDYEYHGI 255 Query: 257 DFDQRVMEHFIKLYKKKT--GKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFE 314 D+ +++HF K + KK KD R++ R++ KLR E E KRALS A +ES + Sbjct: 256 ALDKVLIDHFSKEFLKKNPGAKDPRENPRSLAKLRLEAESTKRALSRSTNASFSVESLID 315 Query: 315 GEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQL 374 G DF+ T+ R ++E + +F + V+ ++ + L D+DE+++ GG++ P+I Sbjct: 316 GLDFASTINRLRYETIARTVFEGFNRLVESAVKKAGLDPLDVDEVIMSGGTSNTPRIAAN 375 Query: 375 VKEFF--------NGKEPSRGINPDEAVAYGAAVQAGVL 405 + F +PS +NP E A GAA+QA ++ Sbjct: 376 FRYIFPESTRILAPSTDPS-ALNPSELQARGAALQASLI 413 >1JCE-A nrPDB Length = 344 Score = 250 bits (637), Expect = 2e-66, Method: Composition-based stats. Identities = 93/379 (24%), Positives = 162/379 (42%), Gaps = 72/379 (18%) Query: 31 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90 +GIDLGT + V F G+ I+ N+ PS +A + T Sbjct: 6 IGIDLGTANTLV--FLRGK-GIVVNE------PSVIAI-------------DSTTGEILK 43 Query: 91 TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150 +AK +IG+T P+ + I+ + V+ T + + + F + M L Sbjct: 44 VGLEAKNMIGKT---PATIKAIRPMRDGVIADYTVALVML-------RYFINKAKGGMNL 93 Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210 K V+ VP D +R+A DAG AG + + +I EP AAAI Sbjct: 94 FK-------------PRVVIGVPIGITDVERRAILDAGLEAGASKVFLIEEPMAAAIGSN 140 Query: 211 LDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLY 270 L+ E N +V D+GGGT +V+++++ + V T + G++ D+ ++++ + Y Sbjct: 141 LNVEEPSGN-MVVDIGGGTTEVAVISLGSIV-----TWESIRIAGDEMDEAIVQYVRETY 194 Query: 271 KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTR------ 324 + G+ R ++++ E+ S+ E+E+ G D S L R Sbjct: 195 RVAIGE------RTAERVKIEIG---NVFPSKEND--ELETTVSGIDLSTGLPRKLTLKG 243 Query: 325 AKFEELNMDLFRSTMKPVQKVLEDSDLK-KSDIDE--IVLVGGSTRIPKIQQLVKEFFNG 381 + E + + ++ V+ LE + + SDI E I L GG + + + L+++ G Sbjct: 244 GEVREALRSVVVAIVESVRTTLEKTPPELVSDIIERGIFLTGGGSLLRGLDTLLQK-ETG 302 Query: 382 KEPSRGINPDEAVAYGAAV 400 R P AVA GA + Sbjct: 303 ISVIRSEEPLTAVAKGAGM 321 >4CZI-A nrPDB Length = 348 Score = 184 bits (468), Expect = 8e-47, Method: Composition-based stats. Identities = 77/374 (20%), Positives = 155/374 (41%), Gaps = 62/374 (16%) Query: 31 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPEN 90 + IDLGT + + ++ G+ I+ N+ PS VA G R + A Sbjct: 6 IAIDLGTANTLI--YQKGK-GIVLNE------PSVVALRNVGGRKVVHA----------- 45 Query: 91 TVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVL 150 +AK+++GRT P + I+ + V+ E++ ++ Sbjct: 46 VGIEAKQMLGRT---PGHMEAIRPMRDGVIADF--------------------EVAEEMI 82 Query: 151 TKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYG 210 G +V VP+ +R+A D+ AG + +I+EP AAAI G Sbjct: 83 KYFIRKVHNRKGSGNPKVIVCVPSGATAVERRAINDSCLNAGARRVGLIDEPMAAAIGAG 142 Query: 211 LDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLY 270 L E + +V D+GGGT +V++L++ V+ + +GG+ D+ ++ + + + Sbjct: 143 LPIHEPTGS-MVVDIGGGTTEVAVLSLSGIVY-----SRSVRVGGDKMDEAIISYMRRHH 196 Query: 271 KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIE--SFFEGEDFSETLTRAKFE 328 G+ +++++E+ A RA + I+++ +G ++ + Sbjct: 197 NLLIGET------TAERIKKEIGTA-RAPADGEGLSIDVKGRDLMQGVPREVRISEKQAA 249 Query: 329 ELNMDLFRSTMKPVQKVLEDSDLK-KSDIDE--IVLVGGSTRIPKIQQLVKEFFNGKEPS 385 + + ++ V+ LE + + SDI + I+L GG + + +++ G + Sbjct: 250 DALAEPVGQIVEAVKVALEATPPELASDIADKGIMLTGGGALLRGLDAEIRDH-TGLPVT 308 Query: 386 RGINPDEAVAYGAA 399 +P VA G Sbjct: 309 VADDPLSCVALGCG 322 >3H1Q-A nrPDB Length = 272 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 44/257 (17%), Positives = 85/257 (33%), Gaps = 57/257 (22%) Query: 146 SAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAA 205 + ++ ++K E LG ++ A +P +A AGL ++ +++EP AA Sbjct: 73 AIQIVRELKAKVERLLGSELFQAATAIPPGTVGRNAEACGHVVAGAGLELVTLVDEPVAA 132 Query: 206 AIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEH 265 A A G++ +V D+GGGT ++++ D GG + Sbjct: 133 ARALGINDG------IVVDIGGGTTGIAVIEKGKITATF-----DEPTGGTHLSLVLAGS 181 Query: 266 FIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRA 325 + + E E K+ S Sbjct: 182 YKIPF-------------------EEAETIKKDFSRHR---------------------- 200 Query: 326 KFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPS 385 + + + V++V+++ D + +VGG+ + + F GKE Sbjct: 201 EIMRVVRPVIEKMALIVKEVIKNYD----QTLPVYVVGGTAYLTGFSEEFSRFL-GKEVQ 255 Query: 386 RGINPDEAVAYGAAVQA 402 I+P G A+ Sbjct: 256 VPIHPLLVTPLGIALFG 272 >5LJV-A nrPDB Length = 347 Score = 52.5 bits (124), Expect = 6e-07, Method: Composition-based stats. Identities = 58/360 (16%), Positives = 121/360 (33%), Gaps = 62/360 (17%) Query: 20 EEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDA 79 E + + +G+DLGT+++ V + + + S V + + Sbjct: 3 EGEGQAKNRLFLGVDLGTSHTAVMSSRGKK----------FLLKSVVGYPKD-------- 44 Query: 80 AKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKT 139 V K L+GR + +++ + ++ Sbjct: 45 ------------VIGLK-LLGRPYVVGDEAFEMRSYLDIRYPLQDGVLSEISDRDI---- 87 Query: 140 FAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRII 199 E++ +LT + ++AE ++ AV+ VPA + A + ++ ++ Sbjct: 88 ----EVARHLLTHVVKSAEPGPNDEIC-AVIGVPARASAANKALLLKMAQEV-VHTALVV 141 Query: 200 NEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFD 259 +EP + YGLDK N ++ D+G GT D+ L G G D Sbjct: 142 SEPF--MVGYGLDKL---INTIIVDIGAGTTDICAL---KGTVPGPEDQVTLTKAGNYVD 193 Query: 260 QRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFS 319 +R+ ++ + + + K + + E G+ Sbjct: 194 ERLQNAILERHPELQ----------MNVNVACAVKEQFSFVGTPTEVASFEFRAAGKPVR 243 Query: 320 ETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLK--KSDIDEIVLVGGSTRIPKIQQLVKE 377 +T + L ++ ++ +L + + + IV GG +RI + VKE Sbjct: 244 ADVT-EPVKIACEALMPDIIESIETLLRSFQPEYQATVLQNIVFAGGGSRIRGLAAYVKE 302 >2YCH-A nrPDB Length = 377 Score = 45.5 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 62/330 (18%), Positives = 116/330 (35%), Gaps = 70/330 (21%) Query: 100 GRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKET--- 156 G ++ Q+IK L ++E +T+ V P ++ M L +M+E Sbjct: 53 GMVAEPAALAQEIKEL---LLEARTRKRYVVTALSNLAVILRPIQVPKMPLKEMEEAVRW 109 Query: 157 -AEAYLGKKVTHAVVTVPAY--FNDAQR----------------QATKDAGTIAGLNVMR 197 AE Y+ + V+ ++ Q +A AGL + Sbjct: 110 EAERYIPFPIDEVVLDFAPLTPLSEVQEGEQVQVMVAAARQEAVAGVLEALRGAGLVPVV 169 Query: 198 IINEPTAAAIAYGLDKR---EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLG 254 + +P A Y L+ R E ++ LV D+G + + LL D + V T L Sbjct: 170 LDVKPFAGL--YPLEARLAEEPDRVFLVLDIGAESTSLVLLRGDKPLAVRVLT-----LS 222 Query: 255 GEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFE 314 G+DF + + R+ E+ KR + E + Sbjct: 223 GKDFTEAI-------------------ARSFNLDLLAAEEVKRTYGMATLPTEDEELLLD 263 Query: 315 GEDFSETLTRAKFEELNMDL-------FRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTR 367 + E + + + + R +++ + LE++ + L+GG ++ Sbjct: 264 FDAERERYSPGRIYDAIRPVLVELTQELRRSLEFFRIQLEEASPEVG-----YLLGGGSK 318 Query: 368 IPKIQQLVKEFFN-GKEPSRGINPDEAVAY 396 + + L+ + EP +NP EAVA Sbjct: 319 LRGLASLLTDTLGVNLEP---VNPWEAVAV 345 >3I8B-A nrPDB Length = 515 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 69/278 (24%), Positives = 99/278 (35%), Gaps = 31/278 (11%) Query: 147 AMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAA 206 AMVL E AE + + +P K IAG NV Sbjct: 218 AMVL----EAAEGAKAAQSHAEAIVLPTVLGPRDAAPVKADPAIAGKNVEG--------- 264 Query: 207 IAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQR-VMEH 265 L G+ + LG DVS+ +GV ++ N L G H Sbjct: 265 -GCLLAPGGGDNAMASLGLGMAVGDVSISLGTSGVAAAISENPTYDLTGAVSGFADCTGH 323 Query: 266 FIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQAR-IEIESFFEGEDF------ 318 ++ L G + RA + + E AK A +S+ A I + +F+GE Sbjct: 324 YLPLACTINGSRILDAGRAALGVDYD-ELAKLAFASKPGANGITLVPYFDGERTPNRPNA 382 Query: 319 -----SETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQ 373 TL E L + + LE + I I+L+GG + I+ Sbjct: 383 TATFSGMTLANTTRENLARAFVEGLLCSQRDCLELIRSLGASITRILLIGGGAKSEAIRT 442 Query: 374 LVKEFFNGKEPSRGINPDEAVAYGAAVQAG-VLSGDQD 410 L G + +R DE VA GAA QA VLSG+ + Sbjct: 443 LAPSIL-GMDVTRPAT-DEYVAIGAARQAAWVLSGETE 478 >2D0P-A nrPDB Length = 610 Score = 37.1 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 42/204 (20%), Positives = 71/204 (34%), Gaps = 11/204 (5%) Query: 205 AAIAYGLDKREGEKNILVFDLGGGTFDVSLLT-IDNGVFEVVATNGDTHLGGEDFDQRVM 263 AAI L + + + DLG G+ D S++ + + +A GD + + Sbjct: 394 AAILGALTTPGTTRPLAILDLGAGSTDASIINPKGDIIATHLAGAGDMVTMIIARELGLE 453 Query: 264 EHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLT 323 + ++ KK + ++ V+ L AR+ + E L Sbjct: 454 DRYLAEEIKKYPLAKVESLFHLRHEDGSVQFFSTPLPPAVFARVCVVKADELVPLPGDLA 513 Query: 324 RAKFEELNMDLFRS-TMKPVQKVLEDSDLK--KSDIDEIVLVGGSTRIPKIQQLVKE--- 377 K + + + L DI +VLVGGS+ ++ QLV + Sbjct: 514 LEKVRAIRRSAKERVFVTNALRALRQVSPTGNIRDIPFVVLVGGSSLDFEVPQLVTDALA 573 Query: 378 ---FFNGKEPSRGIN-PDEAVAYG 397 G+ RG P AVA G Sbjct: 574 HYRLVAGRGNIRGSEGPRNAVATG 597 >5EOY-A nrPDB Length = 357 Score = 36.7 bits (83), Expect = 0.030, Method: Composition-based stats. Identities = 37/211 (17%), Positives = 72/211 (34%), Gaps = 49/211 (23%) Query: 201 EPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQ 260 E + A ++ L + + V D+G +S+L ++ + GG Sbjct: 179 ERSYALLSSQLGADTDQLTVAVVDIGATMTTLSVLHNGRTIYT-----REQLFGGRQ--- 230 Query: 261 RVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSE 320 + +++ G V E AK+ Sbjct: 231 -----LTEEIQRRYGLSV-----------EEAGLAKK---------------------QG 253 Query: 321 TLTRAKFEELNMDLFRSTMKPVQKVLED--SDLKKSDIDEIVLVGGSTRIPKIQQLVKEF 378 L E+ + ++ V + L+ + + +D+D IVL GG+ I + +L+++ Sbjct: 254 GLPDDYDSEVLRPFKDAVVQQVSRSLQFFFAAGQFNDVDYIVLAGGTASIQDLDRLIQQK 313 Query: 379 FNGKEPSRGINPDEAVAYGAAVQAGVLSGDQ 409 P+ NP +A V AG L+ D Sbjct: 314 IG--TPTLVANPFADMALNGKVNAGALASDA 342 >3JAX-A nrPDB Length = 974 Score = 35.1 bits (79), Expect = 0.096, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 16/111 (14%) Query: 534 TPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSL--------------KNQIGDK 579 + E + M + E+F + L++ R ELE SL ++ + D Sbjct: 853 SAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADA 912 Query: 580 EKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPI 630 E+ +L +K +E V+E E LE ++ + E AKK++LE+ + Sbjct: 913 EERCDQLIK-NKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSEL 961 >1NBW-A nrPDB Length = 607 Score = 35.1 bits (79), Expect = 0.098, Method: Composition-based stats. Identities = 50/212 (23%), Positives = 84/212 (39%), Gaps = 29/212 (13%) Query: 206 AIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEV-VATNGD-------THLGGED 257 AIA L + + DLG G+ D +++ + + V +A G+ T LG ED Sbjct: 397 AIAGALTTPGCAAPLAILDLGAGSTDAAIVNAEGQITAVHLAGAGNMVSLLIKTELGLED 456 Query: 258 FDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEI--ESFFEG 315 KK + +++ VE + ALS A++ E Sbjct: 457 LSLA-------EAIKKYPLAKVESLFSIRHENGAVEFFREALSPAVFAKVVYIKEGELVP 509 Query: 316 EDFSETLTRAKF--EELNMDLFR-STMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQ 372 D + L + + + +F + ++ +++V DI +VLVGGS+ +I Sbjct: 510 IDNASPLEKIRLVRRQAKEKVFVTNCLRALRQV--SPGGSIRDIAFVVLVGGSSLDFEIP 567 Query: 373 QLVKEFFN------GKEPSRGIN-PDEAVAYG 397 QL+ E + G+ RG P AVA G Sbjct: 568 QLITEALSHYGVVAGQGNIRGTEGPRNAVATG 599 >3J9V-F nrPDB Length = 517 Score = 34.0 bits (76), Expect = 0.20, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 56/159 (35%), Gaps = 10/159 (6%) Query: 7 AAALLLLCAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEI-------IANDQGN 59 A AL + A R E ++ G + DL T Y G + I + ND Sbjct: 285 ADALREVSAAREEVPGRRGYPGYMY-TDLSTIYERAGRVEGRNGSITQIPILTMPNDDIT 343 Query: 60 RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV 119 P + EG+ + N+ P N + RL+ + ++D + ++ Sbjct: 344 HPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQL 403 Query: 120 VEKK--TKPYIQVDIGGGQTKTFAPEEISAMVLTKMKET 156 K K + G+ +++S L K ++T Sbjct: 404 YAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKT 442 >1C0F-A nrPDB Length = 368 Score = 32.8 bits (73), Expect = 0.45, Method: Composition-based stats. Identities = 41/207 (19%), Positives = 71/207 (34%), Gaps = 33/207 (15%) Query: 228 GTFDVSLLTIDNGV------FEVVATNGDT---HLGGEDFDQRVMEHFIK---LYKKKTG 275 G ++ +GV +E A L G D +M+ + + Sbjct: 139 GRTTGIVMDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAE 198 Query: 276 KDVRKD---NRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKF-EELN 331 +++ +D A L E E A SS + E+ +G+ + R + E L Sbjct: 199 REIVRDIKEKLAYVALDFEAEMQTAASSSALEKSYELP---DGQVITIGNERFRCPEALF 255 Query: 332 MDLFRSTMKPVQKVLEDSDLKKSDID-------EIVLVGGSTRIPKIQQLVKEFFNGKEP 384 F + + K D+D +VL GG+T P I + + P Sbjct: 256 QPSFLGMESAGIHETTYNSIMKCDVDIRKDLYGNVVLSGGTTMFPGIADRMNKELTALAP 315 Query: 385 S----RGINPDE---AVAYGAAVQAGV 404 S + I P E +V G ++ A + Sbjct: 316 STMKIKIIAPPERKYSVWIGGSILASL 342 >4ZXZ-A nrPDB Length = 447 Score = 32.8 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 328 EELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKE 383 +++ + R T + + +IDEI L GG P I + +++ + + Sbjct: 293 DDIVATVTRITAQSIVDAYRRYAPS-QEIDEIFLCGGGAYNPNIVEFIQQAYPNTK 347 >5MLC-9 nrPDB Length = 271 Score = 32.4 bits (72), Expect = 0.65, Method: Composition-based stats. Identities = 30/162 (18%), Positives = 62/162 (38%), Gaps = 9/162 (5%) Query: 470 RPLTKDNHLLGTFDLT--GIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITIT 527 R +L ++ G P + + + QI D + +L ++ DK + + I Sbjct: 114 RTNRASPTMLDRIEVEYYGTPVSLKSIAQISTP---DASSLL-ISPYDKSSLKAIEKAIV 169 Query: 528 NDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLS 587 Q ++P ++ + D++ + E +++N D K KL Sbjct: 170 TSQLGVSPNNDGEVIRLSLPPLTSDRRKELAKVVSKLAEEGKVAVRNIRRDALKSYEKLE 229 Query: 588 PEDK--ETMEKAVEEKIEWLESHQDADIED-FKAKKKELEEI 626 E K E K + ++ L +E +K K++EL ++ Sbjct: 230 KEKKLSEDNVKDLSADLQKLTDEYMKKVESIYKQKEQELMKV 271 >5NKS-A nrPDB Length = 573 Score = 32.4 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 35/91 (38%), Gaps = 11/91 (12%) Query: 119 VVEKKTKPYIQVDIGGGQTKTFA-PEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFN 177 +VE++ K +++ I G + + PEE+ A + + A+ P Y Sbjct: 205 IVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQ----------ANCPLYVT 254 Query: 178 DAQRQATKDAGTIAGLNVMRIINEPTAAAIA 208 + DA A + + EP A++ Sbjct: 255 KVMSKGAADAIAQAKRRGVVVFGEPITASLG 285 >4B3J-A nrPDB Length = 736 Score = 32.1 bits (71), Expect = 0.72, Method: Composition-based stats. Identities = 23/148 (15%), Positives = 52/148 (35%), Gaps = 32/148 (21%) Query: 491 PRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAE 550 P +P + ++ D +GI+ +T +D + N + IE M Sbjct: 14 PNSMPDNTIQWDKDADGIVTLTMDDP----------SGSTNVMNEAYIESM------GKA 57 Query: 551 EDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQD 610 D+ + E+ S+ + K + K ++ E+ Sbjct: 58 VDRLVAEKD-----------SITGVVVASAKKTFFAGGDVKTMIQARPEDA-----GDVF 101 Query: 611 ADIEDFKAKKKELEEIVQPIISKLYGSG 638 +E K + + LE + +P+++ + G+ Sbjct: 102 NTVETIKRQLRTLETLGKPVVAAINGAA 129 >6IRV-A nrPDB Length = 508 Score = 32.1 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 554 KLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADI 613 ++K R + + L YA + + I + SP+ ++ ++ VE+ WL A Sbjct: 113 RIKFREEAKRLLFKYAEAARRLIESRS-----ASPDSRKVVKWNVEDTFSWLRKDHSASK 167 Query: 614 EDFKAKKKELEEIVQPIIS 632 ED+ + + L P +S Sbjct: 168 EDYMDRLEHLRRQCGPHVS 186 >6IRX-A nrPDB Length = 496 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 39/81 (48%), Gaps = 5/81 (6%) Query: 554 KLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADI 613 ++K + + R L YA + K I + ++PE ++ ++ VE+ + WL A Sbjct: 104 RIKYKEEARKLLFKYAEAAKKMIDSRN-----VTPESRKVVKWNVEDTMNWLRRDHSASK 158 Query: 614 EDFKAKKKELEEIVQPIISKL 634 ED+ + + L + P ++ + Sbjct: 159 EDYMDRLENLRKQCGPHVASV 179 >4N44-A nrPDB Length = 400 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Query: 342 VQKVLEDSDLKKSDIDEIV----LVGGSTRIPKIQQLVKEFFNGKEPSRGIN 389 +++ ++ + +K D++E++ L G + P Q K + P+ IN Sbjct: 34 IKEAVKKAGIKPEDVNEVILGNVLQAGLGQNPARQASFKAGLPVEIPAMTIN 85 >4ISJ-A nrPDB Length = 481 Score = 30.5 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 50/151 (33%), Gaps = 3/151 (1%) Query: 99 IGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAE 158 +G + VQ K +V + QV + ++++ L M+ Sbjct: 198 LGSGNHFLEVQVVDKIFDPEVAKAYGLFEGQVVVMVHTGSRGLGHQVASDYLRIMERAIR 257 Query: 159 AYLGKKVTHAVVTVPAYFNDAQRQ--ATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREG 216 Y +V+VP + QR A K A A N I + + EG Sbjct: 258 KYRIPWPDRELVSVPFQSEEGQRYFSAMKAAANFAWANRQMITHWVRESFQEVFKQDPEG 317 Query: 217 E-KNILVFDLGGGTFDVSLLTIDNGVFEVVA 246 + +V+D+ V +D +V+ Sbjct: 318 DLGMDIVYDVAHNIGKVEEHEVDGKRVKVIV 348 >5SVC-B nrPDB Length = 727 Score = 30.5 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 198 IINEPTAAAIAYG-LDKREGEKNILVFDLGGGTFDVSLLTIDNGVFE 243 I++ P I L + G KNI D+GG +FDV+L+T + Sbjct: 292 IVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQGEMTIK 338 >3B2Q-A nrPDB Length = 469 Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 45/129 (34%), Gaps = 8/129 (6%) Query: 4 TVVAAALLLLCAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEI-------IAND 56 T A AL + A R E ++ G + DL T Y G+ K + + + D Sbjct: 259 TNYAEALRQMGAARNEVPGRRGYPGYMY-TDLATLYERAGIVKGAKGSVTQIPILSMPGD 317 Query: 57 QGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLP 116 P + EG+ ++ + P N + RL+ ++D K + Sbjct: 318 DITHPIPDLSGYITEGQIVVARELHRKGIYPPINVLPSLSRLMNSGIGAGKTREDHKAVS 377 Query: 117 FKVVEKKTK 125 ++ + Sbjct: 378 DQMYAGYAE 386 >1E4F-T nrPDB Length = 419 Score = 29.7 bits (65), Expect = 3.8, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 65/177 (36%), Gaps = 17/177 (9%) Query: 211 LDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLY 270 L E ++ ++V +LG L+ NGV ++ +G + + V + Sbjct: 199 LTTPEKDRGVVVVNLGYNFT--GLIAYKNGVPIKISY---VPVGMKHVIKDVSAVLDTSF 253 Query: 271 KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEEL 330 ++ + N L+ E E R L + + A+ E+ Sbjct: 254 EESERLIITHGNAVYNDLKEE-EIQYRGLDGNTIKTTTAKKLSV-------IIHARLREI 305 Query: 331 NMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRG 387 + + K++E+ ++ +VL GG +IP+I +L E F K P R Sbjct: 306 MSKSKKFFREVEAKIVEEGEIGIP--GGVVLTGGGAKIPRINELATEVF--KSPVRT 358 >2DKH-A nrPDB Length = 639 Score = 29.7 bits (65), Expect = 4.0, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 27/88 (30%) Query: 94 DAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKM 153 + +R IGR S Q + V +V I Q ++ Sbjct: 212 NVRRAIGRQLVGDSANQAWGVMDVLAVTDFPDVRYKVAIQSEQGNVLIIPREGGHLVRFY 271 Query: 154 KETAEAYLGKKVTHAVVTVPAYFNDAQR 181 E + ++V +TV AQR Sbjct: 272 VEMDKLDADERVASRNITVEQLIATAQR 299 >1F1M-A nrPDB Length = 164 Score = 29.0 bits (63), Expect = 6.2, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 39/122 (31%), Gaps = 12/122 (9%) Query: 502 EIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDT 561 E D NG L A T KI+ D L E E+ KK E Sbjct: 52 EADHNGSLMSGAYLISTLITKKISAIKDSGELKAE------------IEKAKKCSEEFTA 99 Query: 562 RNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKK 621 + + E + D K + DK +E+ E +++ A E K Sbjct: 100 KLKGEHTDLGKEGVTDDNAKKAILKTNNDKTKGADELEKLFESVKNLSKAAKEMLTNSVK 159 Query: 622 EL 623 EL Sbjct: 160 EL 161 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.125 0.295 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,302,403 Number of Sequences: 36641 Number of extensions: 847268 Number of successful extensions: 2804 Number of sequences better than 10.0: 46 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 75 Number of HSP's that attempted gapping in prelim test: 2642 Number of HSP's gapped (non-prelim): 127 length of query: 654 length of database: 10,336,785 effective HSP length: 103 effective length of query: 551 effective length of database: 6,562,762 effective search space: 3616081862 effective search space used: 3616081862 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 62 (28.6 bits)