BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P06746 (335 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4RQ2-A nrPDB 694 0.0 3K75-D nrPDB 491 e-139 3LQC-B nrPDB 392 e-109 3PMN-A nrPDB 210 8e-55 4P4M-A nrPDB 151 5e-37 4LZG-A nrPDB 122 2e-28 2IHM-A nrPDB 117 6e-27 4QZD-A nrPDB 94 9e-20 3B0X-A nrPDB 93 2e-19 5HRB-A nrPDB 40 0.002 5FOI-A nrPDB 33 0.18 2VA8-A nrPDB 32 0.34 3ZIF-A nrPDB 31 0.60 3CCJ-Y nrPDB 30 1.1 6B11-A nrPDB 30 1.4 2OBE-A nrPDB 30 1.6 6A9U-A nrPDB 28 4.2 5XE0-A nrPDB 28 5.0 5ZZ6-A nrPDB 28 5.4 1R6B-X nrPDB 28 7.1 5MLM-A nrPDB 28 7.9 >4RQ2-A nrPDB Length = 343 Score = 694 bits (1792), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK 60 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK Sbjct: 3 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK 62 Query: 61 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK 120 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK Sbjct: 63 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK 122 Query: 121 TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS 180 TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS Sbjct: 123 TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS 182 Query: 181 FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ 240 FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ Sbjct: 183 FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ 242 Query: 241 LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP 300 LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP Sbjct: 243 LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP 302 Query: 301 LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 335 LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE Sbjct: 303 LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 337 >3K75-D nrPDB Length = 252 Score = 491 bits (1264), Expect = e-139, Method: Compositional matrix adjust. Identities = 232/245 (94%), Positives = 240/245 (97%) Query: 91 DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRI 150 DDTSSSINFLTRV+GIGPSAARK VDEGIKTLEDLRKNEDKLNHHQRIGLKYF DFEKRI Sbjct: 2 DDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRI 61 Query: 151 PREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKL 210 PREEMLQMQDIVLNEVKK+D EYIATVCGSFRRGAESSGDMDVLLTHP+FTSES+KQPKL Sbjct: 62 PREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKL 121 Query: 211 LHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVL 270 LH+VVEQLQKV FITDTLSKGETKFMGVCQLPS+NDE EYPHRRIDIRLIPKDQYYCGVL Sbjct: 122 LHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVL 181 Query: 271 YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREP 330 YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSE+DIFDYIQW+YREP Sbjct: 182 YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREP 241 Query: 331 KDRSE 335 KDRSE Sbjct: 242 KDRSE 246 >3LQC-B nrPDB Length = 200 Score = 392 bits (1006), Expect = e-109, Method: Compositional matrix adjust. Identities = 183/194 (94%), Positives = 190/194 (97%) Query: 142 YFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFT 201 YF DFEKRIPREEMLQMQDIVLNEVKK+D EYIATVCGSFRRGAESSGDMDVLLTHP+FT Sbjct: 1 YFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFT 60 Query: 202 SESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIP 261 SES+KQPKLLH+VVEQLQKV FITDTLSKGETKFMGVCQLPS+NDE EYPHRRIDIRLIP Sbjct: 61 SESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIP 120 Query: 262 KDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFD 321 KDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSE+DIFD Sbjct: 121 KDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFD 180 Query: 322 YIQWKYREPKDRSE 335 YIQW+YREPKDRSE Sbjct: 181 YIQWRYREPKDRSE 194 >3PMN-A nrPDB Length = 329 Score = 210 bits (534), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 122/340 (35%), Positives = 191/340 (56%), Gaps = 24/340 (7%) Query: 2 SKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNA--YRKAASVIAKYPHKIKSGAEA 59 S +KA L+ IT+ L LA K S K+ A Y KA + + + + S EA Sbjct: 4 SSQKATNHNLH--ITEKLEVLA---KAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEA 58 Query: 60 KKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGI 119 +PG+G ++AEKI E L +G LRKL+ I ++ + + + G G A+ + +G Sbjct: 59 CSIPGIGKRMAEKIIEILESGHLRKLDHI--SESVPVLELFSNIWGAGTKTAQMWYQQGF 116 Query: 120 KTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCG 179 ++LED+R ++ L Q IGLK++ DF +R+PREE +++ V + +S + CG Sbjct: 117 RSLEDIR-SQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACG 175 Query: 180 SFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVC 239 S+RRG + GD+DVL+THP S + ++++ L++ F+TD L KGETK++GVC Sbjct: 176 SYRRGKATCGDVDVLITHPDGRSHR----GIFSRLLDSLRQEGFLTDDLVKGETKYLGVC 231 Query: 240 QLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIR 299 +LP HRR+DI ++P ++ C +LYFTGS FN++MRA A KG +++E+ + Sbjct: 232 RLPGPGRR----HRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS 287 Query: 300 PL------GVTGVAGEPLPVDSEKDIFDYIQWKYREPKDR 333 G G LP +EKD+F + YREP +R Sbjct: 288 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAER 327 >4P4M-A nrPDB Length = 378 Score = 151 bits (381), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 113/376 (30%), Positives = 182/376 (48%), Gaps = 45/376 (11%) Query: 1 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK 60 M +RK + I + E+A+ + + + +R S+ + + + K Sbjct: 3 MLRRKFLRRDHRENIIRIFQEMADLNNALGEKYKVSSYHRSIESLKTNLDKPLNTPQDLK 62 Query: 61 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVD-EGI 119 G G K+ +K +E +ATGKL +LE + +I LT+V G GP AA D EGI Sbjct: 63 AFSGFGAKLLKKAEEIMATGKLEELES-KTKPKLKAIQELTQVHGFGPRAAAALFDREGI 121 Query: 120 KTLEDLRKNEDK---LNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKV-DSEYIA 175 T+++L + D L QR+G+KYF D ++IP +E + ++ + + +V ++ Sbjct: 122 FTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSI 181 Query: 176 TVCGSFRRGAESSGDMDVLLTH----PSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKG 231 +CGS+RR SGD+D +L+ P SE +L VE L+ + ++ T+++G Sbjct: 182 LICGSYRRRHPFSGDVDAILSRTLDAPPL-SEPVAATGVLGHFVEFLESLKYLEATMAQG 240 Query: 232 ETKFMGVCQLP--------SKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMR 283 K+MG+ +LP + + K Y RR+DIRLI +L FTGS FN MR Sbjct: 241 PLKYMGMGRLPPRIVRDKAGRENTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMR 300 Query: 284 AHALEKGFTINEYTIRPLGV----------TGV----AGEPL------------PVDSEK 317 A+ KG+ +NEY + LG G+ AGE L V SE+ Sbjct: 301 QAAISKGYLLNEYGLFKLGTPEEARALYERIGIRGKNAGEELGVPKDELEDKRVEVRSEQ 360 Query: 318 DIFDYIQWKYREPKDR 333 D+FD + Y +P++R Sbjct: 361 DVFDVLGMPYAKPENR 376 >4LZG-A nrPDB Length = 356 Score = 122 bits (306), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 88/351 (25%), Positives = 166/351 (47%), Gaps = 30/351 (8%) Query: 2 SKRKAPQETLNGGITD---MLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAE 58 +R P N G+++ +L E A FE + + + + +AASV+ P + + ++ Sbjct: 17 CQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLL----TFCRAASVLKALPSPVTTLSQ 72 Query: 59 AKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEG 118 + LP G + + E L G ++E++R+ + ++ T++ G+G A ++ EG Sbjct: 73 LQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREG 132 Query: 119 IKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVC 178 ++TL+DLR+ KL Q+ GL++ D + R ++ +Q +V V + T+ Sbjct: 133 LRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLT 192 Query: 179 GSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQ-LQKVHFITDTLSKGETKF-- 235 G FRRG D+D L+THP E+ P+++ ++ +Q L H + + T+ Sbjct: 193 GGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSCCESPTRLAQ 252 Query: 236 ----------MGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAH 285 + +LP K R+D+ + P Q+ +L +TGS +F + +R Sbjct: 253 QSHMDAFERSFCIFRLPQPGSWKAV---RVDLVVAPVSQFPFALLGWTGSKLFQRELRRF 309 Query: 286 AL-EKGFTINEYTI-RPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRS 334 + EKG +N + + P T SE+DIF ++ +Y P+ R+ Sbjct: 310 SRKEKGLWLNSHGLFDPEQKTFFQAA-----SEEDIFRHLGLEYLPPEQRN 355 >2IHM-A nrPDB Length = 360 Score = 117 bits (294), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 90/353 (25%), Positives = 156/353 (44%), Gaps = 39/353 (11%) Query: 10 TLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKI 69 TL + L E A FE N + + ++ +AASV+ P + S ++ LP G Sbjct: 18 TLLSEALETLAEAAGFEANEGRLL----SFSRAASVLKSLPCPVASLSQLHGLPYFGEHS 73 Query: 70 AEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNE 129 I E L G +++++R + ++ T+V G+G A ++ EG++TL++LR+ Sbjct: 74 TRVIQELLEHGTCEEVKQVRCSERYQTMKLFTQVFGVGVKTANRWYQEGLRTLDELREQP 133 Query: 130 DKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSG 189 +L Q+ GL+Y+ D + R + +Q ++ V++ T+ G FRRG Sbjct: 134 QRLTQQQKAGLQYYQDLSTPVRRADAEALQQLIEAAVRQTLPGATVTLTGGFRRGKLQGH 193 Query: 190 DMDVLLTHPSFTSESTKQPKLLHQ-------VVEQLQKVHFI---------TDTLSKGET 233 D+D L+THP E PK++ + Q + H + T+ E Sbjct: 194 DVDFLITHPEEGQEVGLLPKVMSCLQSQGLVLYHQYHRSHLADSAHNLRQRSSTMDVFER 253 Query: 234 KF--MGVCQ---------LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNM 282 F +G+ Q LP K R+D+ + P Q+ +L +TGS F + + Sbjct: 254 SFCILGLPQPQQAALAGALPPCPTWKAV---RVDLVVTPSSQFPFALLGWTGSQFFEREL 310 Query: 283 RAHA-LEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRS 334 R + EKG +N + + V SE+D+F + KY P+ R+ Sbjct: 311 RRFSRQEKGLWLNSHGLFDPEQKRV----FHATSEEDVFRLLGLKYLPPEQRN 359 >4QZD-A nrPDB Length = 400 Score = 94.0 bits (232), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 85/349 (24%), Positives = 152/349 (43%), Gaps = 43/349 (12%) Query: 17 DMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEF 76 D+L E +N + A+ +A+SV+ P I S + + +P +G K+ I+ Sbjct: 63 DILAENDELRENEGSCL----AFMRASSVLKSLPFPITSMKDTEGIPCLGDKVKSIIEGI 118 Query: 77 LATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNED-KLNHH 135 + G+ + + + D+ S T V G+G A K+ G +TL ++ ++ + Sbjct: 119 IEDGESSEAKAVLNDERYKSFKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQM 178 Query: 136 QRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLL 195 Q+ G Y+ D + R E + +V V + + T+ G FRRG + D+D L+ Sbjct: 179 QKAGFLYYEDLVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFLI 238 Query: 196 THPSFTSESTKQPKLLHQVVE--QLQKVHFITDTLSKGETKF------------MGVCQL 241 T P T + +Q LLH+V + + Q + D L KF C L Sbjct: 239 TSPEATEDEEQQ--LLHKVTDFWKQQGLLLYCDILESTFEKFKQPSRKVDALDHFQKCAL 296 Query: 242 PSKNDE-------------KEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHAL- 287 K D K + R+D+ + P D+ +L +TGS F +++R +A Sbjct: 297 ILKLDHGRVHSEKSGQQEGKGWKAIRVDLVMCPYDRRAFALLGWTGSRQFERDLRRYATH 356 Query: 288 EKGFTINEYTI--RPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRS 334 E+ ++ + + R V L +SE++IF ++ Y EP +R+ Sbjct: 357 ERKMMLDNHALYDRTKRVF------LEAESEEEIFAHLGLDYIEPWERN 399 >3B0X-A nrPDB Length = 575 Score = 92.8 bits (229), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 81/282 (28%), Positives = 132/282 (46%), Gaps = 40/282 (14%) Query: 35 KYNAYRKAASVIAKYPHKIKSGAEAKK-----LPGVGTKIAEKIDEFLATGKLRKLEKIR 89 + AY +AA + I+ AE K LPGVG +AEKI EFL TGK+RK E++ Sbjct: 26 RVRAYHQAARTLYDLDTPIEEIAEKGKEALMELPGVGPDLAEKILEFLRTGKVRKHEELS 85 Query: 90 QDDTSSSINFLTRVSGIGPSAARKFVDE-GIKTLEDLRKNEDKLN----------HHQRI 138 + + + V G+GP AR + GI +LE L+ D+ + +RI Sbjct: 86 RKVPRGVLEVM-EVPGVGPKTARLLYEGLGIDSLEKLKAALDRGDLTRLKGFGPKRAERI 144 Query: 139 --GLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLT 196 GL KR P +L + +L ++ + A +CGS RR ++ GD+D L+ Sbjct: 145 REGLALAQAAGKRRPLGAVLSLARSLLEAIRALPGVERAELCGSARRYKDTVGDLDFLVA 204 Query: 197 HPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRID 256 + E + VE ++ + + +KG+ + + KN + +D Sbjct: 205 ----SREGER-------AVEGFVRLPQVKEVYAKGKER----ATVFLKNGLQ------VD 243 Query: 257 IRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTI 298 +R++P + Y G+ Y TGS + +RA A EKG ++EY + Sbjct: 244 LRVVPPESYGAGLQYLTGSAAHSIRLRALAQEKGLKLSEYGV 285 >5HRB-A nrPDB Length = 178 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 41/169 (24%), Positives = 76/169 (44%), Gaps = 20/169 (11%) Query: 165 EVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFI 224 ++ K+ S+ I V GS RR + D+D+L+ P + KLL V+ ++ Sbjct: 29 QLIKILSKNIVAV-GSLRREEKMLNDVDLLIIVP--------EKKLLKHVLPNIRIKGLS 79 Query: 225 TDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRA 284 GE K C L + ++K Y ++D+ ++ + +FTG + +RA Sbjct: 80 FSVKVCGERK----CVLFIEWEKKTY---QLDLFTALAEEKPYAIFHFTGPVSYLIRIRA 132 Query: 285 HALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDR 333 +K + +N+Y + PL + +EK++ + + YR PK R Sbjct: 133 ALKKKNYKLNQYGL----FKNQTLVPLKITTEKELIKELGFTYRIPKKR 177 >5FOI-A nrPDB Length = 408 Score = 33.1 bits (74), Expect = 0.18, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 23/40 (57%) Query: 194 LLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGET 233 LL HP +E +QP+L+ V++L + H I D L + T Sbjct: 263 LLRHPETAAELREQPELMPNAVDELLRYHSIADGLRRAAT 302 >2VA8-A nrPDB Length = 715 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 2/63 (3%) Query: 81 KLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNH--HQRI 138 KLR L +D + L ++SG+G AR + GIK L D+ N DK+ + Q++ Sbjct: 640 KLRILNLRVRDGIKEELLELVQISGVGRKRARLLYNNGIKELGDVVMNPDKVKNLLGQKL 699 Query: 139 GLK 141 G K Sbjct: 700 GEK 702 >3ZIF-A nrPDB Length = 911 Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 31/59 (52%), Gaps = 10/59 (16%) Query: 114 FVDEGIKTLEDLRKNEDKLNHHQRIGLKY---------FGDFEKRIPREEMLQMQDIVL 163 +V+ G + D+ N + NHH+ GL+Y F DF ++P ++ +++++L Sbjct: 479 YVNIGTRWSPDVMDNVNPFNHHRNSGLRYRSQLLGNGRFCDFHIQVP-QKFFAIRNLLL 536 >3CCJ-Y nrPDB Length = 241 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 19/27 (70%) Query: 100 LTRVSGIGPSAARKFVDEGIKTLEDLR 126 LT +SG+GPS A + G +++ED+R Sbjct: 17 LTDISGVGPSKAESLREAGFESVEDVR 43 >6B11-A nrPDB Length = 440 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 21/41 (51%) Query: 193 VLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGET 233 VLL HP+ E T P LL V++L + I D L + T Sbjct: 294 VLLQHPTAWRELTVNPGLLPGAVDELLRYLSIADGLRRSAT 334 >2OBE-A nrPDB Length = 932 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 11/37 (29%), Positives = 19/37 (51%) Query: 106 IGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKY 142 + PS +++ G + D N + NHH+ GL+Y Sbjct: 489 VAPSLVDSYINIGARWSLDPMDNVNPFNHHRNAGLRY 525 >6A9U-A nrPDB Length = 455 Score = 28.5 bits (62), Expect = 4.2, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 5/54 (9%) Query: 218 LQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHR-----RIDIRLIPKDQYY 266 L +H + TL K E K +G+ ++ N EK YPH +D+ +PK Y Sbjct: 323 LHDIHEKSITLMKQELKNLGIDKVSGWNVEKLYPHYIGHNLGLDVHDVPKVSRY 376 >5XE0-A nrPDB Length = 468 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 42/93 (45%), Gaps = 13/93 (13%) Query: 45 VIAKYPHKIKSG--AEAKKLPGVGTKIAEKIDEFLATG--KLRKLEK-IRQDDTSSSINF 99 VIA YPHKI AEA K G+ A+K F+ T + L++ R DD F Sbjct: 327 VIASYPHKIDPALLAEAGKHYGLVMTPADKGTSFVDTNWENVTFLKRYFRADD---QYPF 383 Query: 100 LTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKL 132 L I P K + E I+ +D R +D + Sbjct: 384 L-----IHPVMPMKEIHESIRWTKDPRNTQDHV 411 >5ZZ6-A nrPDB Length = 208 Score = 28.1 bits (61), Expect = 5.4, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 113 KFVDEGIKTL--EDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVD 170 + +DEG++ + E+L + D R L YFG+F KR + + D + E+ V Sbjct: 22 RLLDEGVEVVSSEELARRLDLKASQIRKDLSYFGEFGKRGVGYNVEHLYD-AIGEILGVK 80 Query: 171 SEYIATVCGS 180 E+ V G+ Sbjct: 81 KEWKLVVVGA 90 >1R6B-X nrPDB Length = 758 Score = 27.7 bits (60), Expect = 7.1, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 8/65 (12%) Query: 139 GLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVL-LTH 197 G KY GDFEKR + +L+ + N + +D I T+ G+ GA S G +D L Sbjct: 256 GTKYRGDFEKRF--KALLKQLEQDTNSILFIDE--IHTIIGA---GAASGGQVDAANLIK 308 Query: 198 PSFTS 202 P +S Sbjct: 309 PLLSS 313 >5MLM-A nrPDB Length = 411 Score = 27.7 bits (60), Expect = 7.9, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 19/36 (52%) Query: 300 PLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 335 P V GVA P P +E + +YI+ +PKD E Sbjct: 77 PWKVYGVARRPRPAWNEDNPINYIRCDISDPKDTQE 112 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4RQ2-A nrPDB 468 e-132 4LZG-A nrPDB 390 e-109 2IHM-A nrPDB 376 e-105 3PMN-A nrPDB 374 e-104 3K75-D nrPDB 358 2e-99 4QZD-A nrPDB 344 3e-95 4P4M-A nrPDB 333 8e-92 3LQC-B nrPDB 288 2e-78 3B0X-A nrPDB 249 1e-66 5HRB-A nrPDB 147 5e-36 Sequences not found previously or not previously below threshold: 2W9M-A nrPDB 71 1e-12 2VA8-A nrPDB 39 0.002 2ZJ8-A nrPDB 37 0.011 1XX6-A nrPDB 32 0.35 1PZN-A nrPDB 31 0.53 3EWA-A nrPDB 31 0.65 4DEZ-A nrPDB 31 0.84 4FVM-A nrPDB 30 1.3 2DUY-A nrPDB 30 1.5 4EYH-B nrPDB 30 1.6 3VDP-A nrPDB 29 2.8 3IG8-A nrPDB 29 3.9 2V1C-A nrPDB 29 4.0 1BGX-T nrPDB 29 4.0 2CSB-A nrPDB 28 4.9 4GFJ-A nrPDB 27 8.1 5HM5-A nrPDB 27 8.8 >4RQ2-A nrPDB Length = 343 Score = 468 bits (1204), Expect = e-132, Method: Composition-based stats. Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK 60 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK Sbjct: 3 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK 62 Query: 61 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK 120 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK Sbjct: 63 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK 122 Query: 121 TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS 180 TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS Sbjct: 123 TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS 182 Query: 181 FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ 240 FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ Sbjct: 183 FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ 242 Query: 241 LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP 300 LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP Sbjct: 243 LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP 302 Query: 301 LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 335 LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE Sbjct: 303 LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 337 >4LZG-A nrPDB Length = 356 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 86/350 (24%), Positives = 164/350 (46%), Gaps = 28/350 (8%) Query: 2 SKRKAPQETLNGGITD---MLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAE 58 +R P N G+++ +L E A FE + + + + +AASV+ P + + ++ Sbjct: 17 CQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLL----TFCRAASVLKALPSPVTTLSQ 72 Query: 59 AKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEG 118 + LP G + + E L G ++E++R+ + ++ T++ G+G A ++ EG Sbjct: 73 LQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREG 132 Query: 119 IKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVC 178 ++TL+DLR+ KL Q+ GL++ D + R ++ +Q +V V + T+ Sbjct: 133 LRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLT 192 Query: 179 GSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQ-LQKVHFITDTLSKGETKF-- 235 G FRRG D+D L+THP E+ P+++ ++ +Q L H + + T+ Sbjct: 193 GGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSCCESPTRLAQ 252 Query: 236 ----------MGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAH 285 + +LP K R+D+ + P Q+ +L +TGS +F + +R Sbjct: 253 QSHMDAFERSFCIFRLPQPGSWKAV---RVDLVVAPVSQFPFALLGWTGSKLFQRELRRF 309 Query: 286 A-LEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRS 334 + EKG +N + + SE+DIF ++ +Y P+ R+ Sbjct: 310 SRKEKGLWLNSHGLFDPEQKTF----FQAASEEDIFRHLGLEYLPPEQRN 355 >2IHM-A nrPDB Length = 360 Score = 376 bits (965), Expect = e-105, Method: Composition-based stats. Identities = 91/364 (25%), Positives = 159/364 (43%), Gaps = 42/364 (11%) Query: 2 SKRKAPQETLNG---GITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAE 58 +R +P N + L E A FE N + + ++ +AASV+ P + S ++ Sbjct: 7 CQRPSPLTHHNTLLSEALETLAEAAGFEANEGRLL----SFSRAASVLKSLPCPVASLSQ 62 Query: 59 AKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEG 118 LP G I E L G +++++R + ++ T+V G+G A ++ EG Sbjct: 63 LHGLPYFGEHSTRVIQELLEHGTCEEVKQVRCSERYQTMKLFTQVFGVGVKTANRWYQEG 122 Query: 119 IKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVC 178 ++TL++LR+ +L Q+ GL+Y+ D + R + +Q ++ V++ T+ Sbjct: 123 LRTLDELREQPQRLTQQQKAGLQYYQDLSTPVRRADAEALQQLIEAAVRQTLPGATVTLT 182 Query: 179 GSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQ-------VVEQLQKVHFI------- 224 G FRRG D+D L+THP E PK++ + Q + H Sbjct: 183 GGFRRGKLQGHDVDFLITHPEEGQEVGLLPKVMSCLQSQGLVLYHQYHRSHLADSAHNLR 242 Query: 225 --TDTLSKGETKF--MGVCQ---------LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLY 271 + T+ E F +G+ Q LP K R+D+ + P Q+ +L Sbjct: 243 QRSSTMDVFERSFCILGLPQPQQAALAGALPPCPTWKAV---RVDLVVTPSSQFPFALLG 299 Query: 272 FTGSDIFNKNMRAHA-LEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREP 330 +TGS F + +R + EKG +N + + V SE+D+F + KY P Sbjct: 300 WTGSQFFERELRRFSRQEKGLWLNSHGLFDPEQKRV----FHATSEEDVFRLLGLKYLPP 355 Query: 331 KDRS 334 + R+ Sbjct: 356 EQRN 359 >3PMN-A nrPDB Length = 329 Score = 374 bits (961), Expect = e-104, Method: Composition-based stats. Identities = 122/341 (35%), Positives = 189/341 (55%), Gaps = 24/341 (7%) Query: 2 SKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNA--YRKAASVIAKYPHKIKSGAEA 59 S +KA L+ IT+ L LA K S K+ A Y KA + + + + S EA Sbjct: 4 SSQKATNHNLH--ITEKLEVLA---KAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEA 58 Query: 60 KKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGI 119 +PG+G ++AEKI E L +G LRKL+ I ++ + + + G G A+ + +G Sbjct: 59 CSIPGIGKRMAEKIIEILESGHLRKLDHI--SESVPVLELFSNIWGAGTKTAQMWYQQGF 116 Query: 120 KTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCG 179 ++LED+R L Q IGLK++ DF +R+PREE +++ V + +S + CG Sbjct: 117 RSLEDIRSQA-SLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACG 175 Query: 180 SFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVC 239 S+RRG + GD+DVL+THP S + ++++ L++ F+TD L KGETK++GVC Sbjct: 176 SYRRGKATCGDVDVLITHPDGRSHR----GIFSRLLDSLRQEGFLTDDLVKGETKYLGVC 231 Query: 240 QLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIR 299 +LP HRR+DI ++P ++ C +LYFTGS FN++MRA A KG +++E+ + Sbjct: 232 RLPGPGRR----HRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALS 287 Query: 300 PL------GVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRS 334 G G LP +EKD+F + YREP +R Sbjct: 288 TAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERD 328 >3K75-D nrPDB Length = 252 Score = 358 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 232/245 (94%), Positives = 240/245 (97%) Query: 91 DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRI 150 DDTSSSINFLTRV+GIGPSAARK VDEGIKTLEDLRKNEDKLNHHQRIGLKYF DFEKRI Sbjct: 2 DDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRI 61 Query: 151 PREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKL 210 PREEMLQMQDIVLNEVKK+D EYIATVCGSFRRGAESSGDMDVLLTHP+FTSES+KQPKL Sbjct: 62 PREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKL 121 Query: 211 LHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVL 270 LH+VVEQLQKV FITDTLSKGETKFMGVCQLPS+NDE EYPHRRIDIRLIPKDQYYCGVL Sbjct: 122 LHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVL 181 Query: 271 YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREP 330 YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSE+DIFDYIQW+YREP Sbjct: 182 YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREP 241 Query: 331 KDRSE 335 KDRSE Sbjct: 242 KDRSE 246 >4QZD-A nrPDB Length = 400 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 85/365 (23%), Positives = 154/365 (42%), Gaps = 42/365 (11%) Query: 2 SKRKAPQETLN---GGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAE 58 +R+ N D+L E +N + A+ +A+SV+ P I S + Sbjct: 45 CQRRTTLNNYNQLFTDALDILAENDELRENEGSCL----AFMRASSVLKSLPFPITSMKD 100 Query: 59 AKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEG 118 + +P +G K+ I+ + G+ + + + D+ S T V G+G A K+ G Sbjct: 101 TEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYKSFKLFTSVFGVGLKTAEKWFRMG 160 Query: 119 IKTLEDLRKNED-KLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATV 177 +TL ++ ++ + Q+ G Y+ D + R E + +V V + + T+ Sbjct: 161 FRTLSKIQSDKSLRFTQMQKAGFLYYEDLVSCVNRPEAEAVSMLVKEAVVTFLPDALVTM 220 Query: 178 CGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVE--QLQKVHFITDTLSKGETKF 235 G FRRG + D+D L+T P T + +Q LLH+V + + Q + D L KF Sbjct: 221 TGGFRRGKMTGHDVDFLITSPEATEDEEQQ--LLHKVTDFWKQQGLLLYCDILESTFEKF 278 Query: 236 ------------MGVCQLPSKNDE-------------KEYPHRRIDIRLIPKDQYYCGVL 270 C L K D K + R+D+ + P D+ +L Sbjct: 279 KQPSRKVDALDHFQKCALILKLDHGRVHSEKSGQQEGKGWKAIRVDLVMCPYDRRAFALL 338 Query: 271 YFTGSDIFNKNMRAHAL-EKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYRE 329 +TGS F +++R +A E+ ++ + + L +SE++IF ++ Y E Sbjct: 339 GWTGSRQFERDLRRYATHERKMMLDNHALYDRTKRVF----LEAESEEEIFAHLGLDYIE 394 Query: 330 PKDRS 334 P +R+ Sbjct: 395 PWERN 399 >4P4M-A nrPDB Length = 378 Score = 333 bits (853), Expect = 8e-92, Method: Composition-based stats. Identities = 110/376 (29%), Positives = 179/376 (47%), Gaps = 43/376 (11%) Query: 1 MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK 60 M +RK + I + E+A+ + + + +R S+ + + + K Sbjct: 3 MLRRKFLRRDHRENIIRIFQEMADLNNALGEKYKVSSYHRSIESLKTNLDKPLNTPQDLK 62 Query: 61 KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVD-EGI 119 G G K+ +K +E +ATGKL +LE + +I LT+V G GP AA D EGI Sbjct: 63 AFSGFGAKLLKKAEEIMATGKLEELES-KTKPKLKAIQELTQVHGFGPRAAAALFDREGI 121 Query: 120 KTLEDLRKNED---KLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDS-EYIA 175 T+++L + D L QR+G+KYF D ++IP +E + ++ + + +V ++ Sbjct: 122 FTVDELLQKADSIPSLTDQQRVGIKYFYDINEKIPMQESVLHENYLREKCMEVLGKDFSI 181 Query: 176 TVCGSFRRGAESSGDMDVLLTH---PSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGE 232 +CGS+RR SGD+D +L+ SE +L VE L+ + ++ T+++G Sbjct: 182 LICGSYRRRHPFSGDVDAILSRTLDAPPLSEPVAATGVLGHFVEFLESLKYLEATMAQGP 241 Query: 233 TKFMGVCQLP--------SKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRA 284 K+MG+ +LP + + K Y RR+DIRLI +L FTGS FN MR Sbjct: 242 LKYMGMGRLPPRIVRDKAGRENTKVYKARRVDIRLIETKSVPTAMLTFTGSKNFNVIMRQ 301 Query: 285 HALEKGFTINEYTIRPLGV---------------------TGVAGEPL-----PVDSEKD 318 A+ KG+ +NEY + LG GV + L V SE+D Sbjct: 302 AAISKGYLLNEYGLFKLGTPEEARALYERIGIRGKNAGEELGVPKDELEDKRVEVRSEQD 361 Query: 319 IFDYIQWKYREPKDRS 334 +FD + Y +P++R Sbjct: 362 VFDVLGMPYAKPENRD 377 >3LQC-B nrPDB Length = 200 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 183/194 (94%), Positives = 190/194 (97%) Query: 142 YFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFT 201 YF DFEKRIPREEMLQMQDIVLNEVKK+D EYIATVCGSFRRGAESSGDMDVLLTHP+FT Sbjct: 1 YFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFT 60 Query: 202 SESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIP 261 SES+KQPKLLH+VVEQLQKV FITDTLSKGETKFMGVCQLPS+NDE EYPHRRIDIRLIP Sbjct: 61 SESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIP 120 Query: 262 KDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFD 321 KDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSE+DIFD Sbjct: 121 KDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFD 180 Query: 322 YIQWKYREPKDRSE 335 YIQW+YREPKDRSE Sbjct: 181 YIQWRYREPKDRSE 194 >3B0X-A nrPDB Length = 575 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 89/342 (26%), Positives = 153/342 (44%), Gaps = 46/342 (13%) Query: 12 NGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKK-----LPGVG 66 N + + E+ + + + AY +AA + I+ AE K LPGVG Sbjct: 3 NQELARIFEEIGLMSEFLGDNPFRVRAYHQAARTLYDLDTPIEEIAEKGKEALMELPGVG 62 Query: 67 TKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDE-GIKTLEDL 125 +AEKI EFL TGK+RK E++ + + + V G+GP AR + GI +LE L Sbjct: 63 PDLAEKILEFLRTGKVRKHEELSRKVPRGVLEVM-EVPGVGPKTARLLYEGLGIDSLEKL 121 Query: 126 RKNEDKLN----------HHQRI--GLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEY 173 + D+ + +RI GL KR P +L + +L ++ + Sbjct: 122 KAALDRGDLTRLKGFGPKRAERIREGLALAQAAGKRRPLGAVLSLARSLLEAIRALPGVE 181 Query: 174 IATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGET 233 A +CGS RR ++ GD+D L+ + VE ++ + + +KG+ Sbjct: 182 RAELCGSARRYKDTVGDLDFLVASREG-----------ERAVEGFVRLPQVKEVYAKGKE 230 Query: 234 KFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTI 293 + + KN ++D+R++P + Y G+ Y TGS + +RA A EKG + Sbjct: 231 R----ATVFLKNGL------QVDLRVVPPESYGAGLQYLTGSAAHSIRLRALAQEKGLKL 280 Query: 294 NEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE 335 +EY + G +AGE +E++++ + + P R + Sbjct: 281 SEYGVF-RGEKRIAGE-----TEEEVYAALGLPWIPPPLRED 316 >5HRB-A nrPDB Length = 178 Score = 147 bits (371), Expect = 5e-36, Method: Composition-based stats. Identities = 41/169 (24%), Positives = 75/169 (44%), Gaps = 20/169 (11%) Query: 165 EVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFI 224 ++ K+ S+ I V GS RR + D+D+L+ P KLL V+ ++ Sbjct: 29 QLIKILSKNIVAV-GSLRREEKMLNDVDLLIIVPE--------KKLLKHVLPNIRIKGLS 79 Query: 225 TDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRA 284 GE K C L + ++K Y ++D+ ++ + +FTG + +RA Sbjct: 80 FSVKVCGERK----CVLFIEWEKKTY---QLDLFTALAEEKPYAIFHFTGPVSYLIRIRA 132 Query: 285 HALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDR 333 +K + +N+Y + PL + +EK++ + + YR PK R Sbjct: 133 ALKKKNYKLNQYGLF----KNQTLVPLKITTEKELIKELGFTYRIPKKR 177 >2W9M-A nrPDB Length = 578 Score = 70.6 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 69/340 (20%), Positives = 113/340 (33%), Gaps = 53/340 (15%) Query: 7 PQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKY--PHKIKSGAEAKKLPG 64 P + L A+ + K AYR AA + + E +P Sbjct: 5 PDAPSRHRLVHALERTADLLDILGGEDFKSRAYRSAARSLEELNEETPELLAREFTGIPK 64 Query: 65 VGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLED 124 VG IA ++ +F +G LE ++ V G+GP R GI +LE Sbjct: 65 VGKGIAAELSDFARSGTFAPLEAAAGQLPPGLLDL-LGVRGLGPKKIRSLWLAGIDSLER 123 Query: 125 LRKNEDKLNHHQRIGLKYFGD------FEKRIPREEMLQMQDI-----VLNEVKKVDSEY 173 LR+ + + GLK FG E + E Q Q + V E+ ++ Sbjct: 124 LREAAESG---ELAGLKGFGAKSAATILENVVFLFEARQRQSLRAGLAVAEELAGALTDL 180 Query: 174 IATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGET 233 G RRG E+ ++ +T + L ++ E Sbjct: 181 SPAPAGDVRRGLETVRAAELTVTGTPD---------------DVLARLP---------EL 216 Query: 234 KFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTI 293 G L Y ++I P + L +G + F ++A A +GFT+ Sbjct: 217 TVQGDGVLSGD-----YEGVPVEIACAPAEARGALDLLRSG-EHFAGQVQAAAQARGFTL 270 Query: 294 NEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDR 333 + E LP +E +F + +R + R Sbjct: 271 TAGGLSR------GDEVLPTPTEAVVFHALDLPFRPAEYR 304 >2VA8-A nrPDB Length = 715 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 81 KLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHH--QRI 138 KLR L +D + L ++SG+G AR + GIK L D+ N DK+ + Q++ Sbjct: 640 KLRILNLRVRDGIKEELLELVQISGVGRKRARLLYNNGIKELGDVVMNPDKVKNLLGQKL 699 Query: 139 GLKYFGDFEKRIPR 152 G K + + + R Sbjct: 700 GEKVVQEAARLLNR 713 >2ZJ8-A nrPDB Length = 720 Score = 37.1 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 33/84 (39%), Gaps = 4/84 (4%) Query: 69 IAEKIDEFLATGKLRKLEKIRQDDTSSSINFL---TRVSGIGPSAARKFVDEGIKTLEDL 125 + E A + LE +R L ++ +G AR + G +++ED+ Sbjct: 614 LKEIAKVLGAYEIVDYLETLRVRVKYGIREELIPLMQLPLVGRRRARALYNSGFRSIEDI 673 Query: 126 -RKNEDKLNHHQRIGLKYFGDFEK 148 + ++L + IG+K K Sbjct: 674 SQARPEELLKIEGIGVKTVEAIFK 697 >1XX6-A nrPDB Length = 191 Score = 32.1 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 46/121 (38%), Gaps = 8/121 (6%) Query: 71 EKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNED 130 E I + +GK +L IR+ + +V P ++ E + + ++ Sbjct: 11 EVIVGPMYSGKSEEL--IRRIRRAKIAKQKIQVFK--PEIDNRYSKEDVVSHMGEKEQAV 66 Query: 131 KLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFR---RGAES 187 + + + I LKYF + + I +E+ D ++ V K+ +C RG Sbjct: 67 AIKNSREI-LKYFEEDTEVIAIDEVQFFDDEIVEIVNKIAESGRRVICAGLDMDFRGKPF 125 Query: 188 S 188 Sbjct: 126 G 126 >1PZN-A nrPDB Length = 349 Score = 31.3 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Query: 66 GTKIAEKIDEFLATG-KLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLED 124 G ++ E IDEF G + E ++ I + + G+GP+ A K + G TLE Sbjct: 3 GEEVKE-IDEFEELGFEPATEETPKKKKKEKIIRSIEDLPGVGPATAEKLREAGYDTLEA 61 Query: 125 L 125 + Sbjct: 62 I 62 >3EWA-A nrPDB Length = 322 Score = 31.3 bits (69), Expect = 0.65, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 14/22 (63%) Query: 98 NFLTRVSGIGPSAARKFVDEGI 119 + LT + G+GPS A K ++ G Sbjct: 3 DVLTELPGVGPSTADKLIEGGY 24 >4DEZ-A nrPDB Length = 356 Score = 30.9 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 103 VSGIGPSAARKFVDEGIKTLEDLR-KNEDKLNHH 135 + G+GP +K GI T+ DL + L Sbjct: 183 LWGVGPKTTKKLAAMGITTVADLAVTDPSVLTTA 216 >4FVM-A nrPDB Length = 910 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 37/101 (36%), Gaps = 15/101 (14%) Query: 190 DMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKE 249 D+D L + P + P+LL +V++ ++V + T + + Sbjct: 541 DIDELPSVPPSEVDQGVLPRLLANLVDRRREVKKVMKTETDPHKRVQC------------ 588 Query: 250 YPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKG 290 R+ ++L Y C L + S + K + KG Sbjct: 589 -DIRQQALKLTANSMYGC--LGYVNSRFYAKPLAMLVTNKG 626 >2DUY-A nrPDB Length = 75 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 23/61 (37%), Gaps = 15/61 (24%) Query: 54 KSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARK 113 S E LPG+G +A +I E + + L +V GIGP+ + Sbjct: 24 ASLEELMALPGIGPVLARRIVE---------------GRPYARVEDLLKVKGIGPATLER 68 Query: 114 F 114 Sbjct: 69 L 69 >4EYH-B nrPDB Length = 420 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 57/145 (39%), Gaps = 26/145 (17%) Query: 96 SINFLTRVSGIGPSAARKFVDEGIKTLEDLR-------KNEDKLNHHQRIGLKYFGDFEK 148 S+N + + GIG A+ GI ++ DL+ + E ++ QRI FG+ Sbjct: 232 SLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNS 291 Query: 149 RIPR---EEMLQMQDIV---------LNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLT 196 + + +D N+++++ + + VC R+ + +++ Sbjct: 292 PVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQDGRK----PHTVRLIIR 347 Query: 197 HPSFTSESTKQPK---LLHQVVEQL 218 S ++ + + V+++L Sbjct: 348 RYSSEKHYGRESRQCPIPSHVIQKL 372 >3VDP-A nrPDB Length = 212 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 7/20 (35%), Positives = 12/20 (60%) Query: 95 SSINFLTRVSGIGPSAARKF 114 I L+++ GIGP A++ Sbjct: 23 KLIEELSKLPGIGPKTAQRL 42 >3IG8-A nrPDB Length = 692 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 5/94 (5%) Query: 192 DVLLT-HPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEY 250 D L+ P + S P + +Q + + I+ + K GV L K ++ + Sbjct: 284 DALVNFAPIMLAFSAAAPAFKGWLADQDVRWNVISGAVDDRTPKERGVAPLLPKYNKNGF 343 Query: 251 PHRRIDI----RLIPKDQYYCGVLYFTGSDIFNK 280 D+ IPK +Y L+ GS FN+ Sbjct: 344 GGIAKDVQDKVLEIPKSRYSSVDLFLGGSKFFNR 377 >2V1C-A nrPDB Length = 220 Score = 28.6 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 3/39 (7%) Query: 94 SSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKL 132 S I L+R+ GIGP +A++ E R++ ++L Sbjct: 8 VSLIRELSRLPGIGPKSAQRL---AFHLFEQPREDIERL 43 >1BGX-T nrPDB Length = 832 Score = 28.6 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 103 VSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGD 145 V GIG ARK ++E +LE L KN D+L R + D Sbjct: 196 VKGIGEKTARKLLEE-WGSLEALLKNLDRLKPAIREKILAHMD 237 >2CSB-A nrPDB Length = 519 Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 40/112 (35%), Gaps = 12/112 (10%) Query: 6 APQETLNGGITD-MLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPG 64 P TL D L E + + ++ I ++ AA + + + G Sbjct: 329 TPYRTLKDVCPDLTLEEAKSVNRTLATLIDEHGLSPDAADEL---------IEHFESIAG 379 Query: 65 VGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVD 116 + E+I+ G+L + E R + LT+ G+G A + + Sbjct: 380 ILATDLEEIERMYEEGRLSE-EAYRAAVEIQ-LAELTKKEGVGRKTAERLLR 429 >4GFJ-A nrPDB Length = 685 Score = 27.4 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 40/112 (35%), Gaps = 12/112 (10%) Query: 6 APQETLNGGITD-MLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPG 64 P TL D L E + + ++ I ++ AA + + + G Sbjct: 329 TPYRTLKDVCPDLTLEEAKSVNRTLATLIDEHGLSPDAADEL---------IEHFESIAG 379 Query: 65 VGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVD 116 + E+I+ G+L + E R + LT+ G+G A + + Sbjct: 380 ILATDLEEIERMYEEGRLSE-EAYRAAVEIQ-LAELTKKEGVGRKTAERLLR 429 >5HM5-A nrPDB Length = 854 Score = 27.4 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 40/112 (35%), Gaps = 12/112 (10%) Query: 6 APQETLNGGITD-MLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPG 64 P TL D L E + + ++ I ++ AA + + + G Sbjct: 329 TPYRTLKDVCPDLTLEEAKSVNRTLATLIDEHGLSPDAADEL---------IEHFESIAG 379 Query: 65 VGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVD 116 + E+I+ G+L + E R + LT+ G+G A + + Sbjct: 380 ILATDLEEIERMYEEGRLSE-EAYRAAVEIQ-LAELTKKEGVGRKTAERLLR 429 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.124 0.291 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,563,016 Number of Sequences: 36641 Number of extensions: 378919 Number of successful extensions: 1404 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 1309 Number of HSP's gapped (non-prelim): 76 length of query: 335 length of database: 10,336,785 effective HSP length: 98 effective length of query: 237 effective length of database: 6,745,967 effective search space: 1598794179 effective search space used: 1598794179 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.4 bits)