BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P06709 (321 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2EWN-A nrPDB 642 0.0 3V7C-A nrPDB 95 4e-20 3FJP-A nrPDB 83 1e-16 2EJ9-A nrPDB 77 8e-15 4XU2-A nrPDB 76 2e-14 2FYK-A nrPDB 73 1e-13 6CK0-A nrPDB 57 9e-09 5JP0-A nrPDB 38 0.006 2B3Z-A nrPDB 30 0.98 1JX7-A nrPDB 28 4.1 1JPH-A nrPDB 28 4.6 1CD1-A nrPDB 28 6.3 4V83-BQ nrPDB 28 6.8 2Y4O-A nrPDB 27 9.0 5HCE-A nrPDB 27 9.9 >2EWN-A nrPDB Length = 321 Score = 642 bits (1656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/321 (100%), Positives = 321/321 (100%) Query: 1 MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL 60 MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL Sbjct: 1 MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL 60 Query: 61 PEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG 120 PEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG Sbjct: 61 PEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG 120 Query: 121 RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ 180 RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ Sbjct: 121 RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ 180 Query: 181 DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA 240 DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA Sbjct: 181 DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA 240 Query: 241 MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL 300 MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL Sbjct: 241 MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL 300 Query: 301 EQDGIIKPWMGGEISLRSAEK 321 EQDGIIKPWMGGEISLRSAEK Sbjct: 301 EQDGIIKPWMGGEISLRSAEK 321 >3V7C-A nrPDB Length = 329 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 73/291 (25%), Positives = 127/291 (43%), Gaps = 8/291 (2%) Query: 21 SGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGS 80 SG+ + E+L +SR A+ K I L+ G + +V KG+ L + + + I+ Q S Sbjct: 21 SGQSIAESLNISRTAVKKVIDQLKLEGCKIDSVNHKGHLLQQLPDIW-YQGIIDQYTKSS 79 Query: 81 V-----AVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSM 135 V IDST + +S +++ Q GRGR R W S G L++S+ Sbjct: 80 ALFDFSEVYDSIDSTQLAAKKSLVGNQSSFFILSDEQTKGRGRFNRHWSSSKGQGLWMSV 139 Query: 136 FWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKT 195 R + +L I + + + ++ D+V+VKWPND+Y+ + K+ G L E+ Sbjct: 140 VLRPNVAFSMISKFNLFIALGIRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANN 199 Query: 196 GDAAQIVIGAGINMA--MRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELF 253 I+ G GIN+ + +ES+ ++ LDR L++E+ F Sbjct: 200 DGIEAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLDRYQFLERLLQEIEKRYNQF 259 Query: 254 EQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDG 304 + + N NR + DK+ G + +D G L++ + Sbjct: 260 LTLPFSEIREEYIAASNIWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEA 310 >3FJP-A nrPDB Length = 233 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 124/237 (52%), Gaps = 12/237 (5%) Query: 84 LPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGP 143 L +DST + L + + G A +A+ Q GRGR GRKW S G LY S ++ Sbjct: 8 LKEVDSTQERLKE--WNVSYGTALVADRQTKGRGRLGRKWLSQEGG-LYFSFLLNPKEFE 64 Query: 144 AAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVI 203 ++ V +E L ++ +KWPND+Y Q++K++G+L EL+ ++++ Sbjct: 65 NLLQLPLVLGLSV-SEALEEITEIPFSLKWPNDVYFQEKKVSGVLRELS-----KDKLIV 118 Query: 204 GAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLS 263 G GIN+ R + E + ++ + G + DR + +++ + L+ F+++ + Sbjct: 119 GIGINVNQREIPEEIKDRATTLYEITGKDWDRKEVLLKVLKRISENLKKFKEKSFKEFKG 178 Query: 264 RWEKLDNFINRPVKLIIGDKEIFGISRGI-DKQGALLLEQDGIIKPWMGGEISLRSA 319 + E ++ VKL +G+ +I G G+ +K GAL+L ++G IK + GE SLR + Sbjct: 179 KIESKMLYLGEEVKL-LGEGKITGKLVGLSEKGGALILTEEG-IKEILSGEFSLRRS 233 >2EJ9-A nrPDB Length = 237 Score = 77.4 bits (189), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 73/242 (30%), Positives = 122/242 (50%), Gaps = 18/242 (7%) Query: 84 LPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGP 143 L IDSTN Y + E K +A+ Q G+GR GR W+S G LY SM L+ Sbjct: 6 LSEIDSTNDYAKELAKEGKRNFIVLADKQNNGKGRWGRVWYSDEGG-LYFSMV--LDSKL 62 Query: 144 AAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ----DRKLAGILVELTGKTGDAA 199 ++L++ I + EVL+ ++ +K+PND+ ++ +KL GIL ELT Sbjct: 63 YNPKVINLLVPICIIEVLKNYVDKELGLKFPNDIMVKVNDNYKKLGGILTELTD-----D 117 Query: 200 QIVIGAGINMAMRRVEESVVNQGWITLQE-AGINLDRNTLAAMLIRELRAALELFEQEGL 258 ++IG GIN+ + E + + I+L+E G LD+ + + ++ + LE + + + Sbjct: 118 YMIIGIGINVNNQIRNE--IREIAISLKEITGKELDKVEILSNFLKTFESYLEKLKNKEI 175 Query: 259 APY--LSRWEKLDNFINRPVKLIIGDKEIF-GISRGIDKQGALLLEQDGIIKPWMGGEIS 315 Y L +++K I + VK+++ + EI G ID G +L + GI + G I Sbjct: 176 DDYEILKKYKKYSITIGKQVKILLSNNEIITGKVYDIDFDGIVLGTEKGIERIPSGICIH 235 Query: 316 LR 317 +R Sbjct: 236 VR 237 >4XU2-A nrPDB Length = 270 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 84/249 (33%), Positives = 124/249 (49%), Gaps = 24/249 (9%) Query: 65 QLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRI--GELKSGDACIAEYQQAGRGRRGRK 122 QL+ A QLD V+ STN LL R G G IAE+Q AGRGR GR Sbjct: 23 QLIGAGSGWRQLD-----VVAQTGSTNADLLARAASGADIDGVVLIAEHQTAGRGRHGRG 77 Query: 123 WFSPFGANLYLSMFWRLEQGPAAAIG-LSLVIGIVMAEVLRKLGA---DKVRVKWPNDLY 178 W + A + LS+ R+ P A G LSL G+ + + + L A + +KWPND+ Sbjct: 78 WAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAETGLKWPNDVL 137 Query: 179 LQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINL-DRNT 237 + KLAGIL E+ +V+G G+N+ E V+ +L + G+ DRN Sbjct: 138 ARGGKLAGILAEVAQPF-----VVLGVGLNVTQAPEE---VDPDATSLLDLGVAAPDRNR 189 Query: 238 LAAMLIRELRAALELFEQEGLAPYLSRWEKLDNF-INRPVKL-IIGDKEIFGISRGIDKQ 295 +A+ L+REL A + + P L+ + + I V++ + G +++ GI+R ID Q Sbjct: 190 IASRLLRELEA--RIIQWRNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIARDIDDQ 247 Query: 296 GALLLEQDG 304 G L L+ G Sbjct: 248 GRLCLDVGG 256 >2FYK-A nrPDB Length = 235 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 76/235 (32%), Positives = 111/235 (47%), Gaps = 24/235 (10%) Query: 87 IDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFW--RLEQGPA 144 I STN++ + L+ G +A+ Q G GR RKW SP G L+LS+ ++ Q Sbjct: 19 ITSTNEFA--KTSYLEEGTVIVADKQTMGHGRLNRKWESPEGG-LWLSIVLSPKVPQKDL 75 Query: 145 AAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIG 204 I +G+V E L++ D R+KWPND+ + +K+AG+LVE G +IV+G Sbjct: 76 PKIVFLGAVGVV--ETLKEFSIDG-RIKWPNDVLVNYKKIAGVLVE-----GKGDKIVLG 127 Query: 205 AGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIREL-RAALELFEQEGLAPYLS 263 G+N V V N E G + ++ LI L R L + L Sbjct: 128 IGLN-----VNNKVPNGATSMKLELGSEVPLLSVFRSLITNLDRLYLNFLKNPMDILNLV 182 Query: 264 RWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQD-GIIKPWMGGEISLR 317 R DN I I+GD GI+ ID G L++ D G +K + G++SLR Sbjct: 183 R----DNMILGVRVKILGDGSFEGIAEDIDDFGRLIIRLDSGEVKKVIYGDVSLR 233 >6CK0-A nrPDB Length = 220 Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 11/135 (8%) Query: 83 VLPVIDSTNQYLLDRI--GELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLE 140 V + ST YLL+++ ELK+ +A+ Q G G RG W A L S+ Sbjct: 16 VFDSLPSTQTYLLEKLKNNELKAPILIVAKNQSTGIGSRGNIWEGTKSA-LTFSLALNAS 74 Query: 141 QGPA--AAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDA 198 P +L +G + EVL++LG+ + +KWPNDLYL D+K+ G+LV + Sbjct: 75 DLPKDLPMQANALYLGFLFKEVLKELGS-QTWLKWPNDLYLGDQKIGGVLVNVY-----K 128 Query: 199 AQIVIGAGINMAMRR 213 V G G+N ++ Sbjct: 129 GMRVCGIGVNRVSKK 143 >5JP0-A nrPDB Length = 772 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 18/114 (15%) Query: 197 DAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQE 256 +A +IVI AGI+M+M E S + ++E ++++R A + L+ L LF+ Sbjct: 311 EAVKIVINAGIDMSMVPYEVSFCDYLKELVEEGEVSMERIDDAVARVLRLKYRLGLFDH- 369 Query: 257 GLAPYLSRWE--KLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKP 308 PY W+ K D F G KE ++ ++ +LL+ DG I P Sbjct: 370 ---PY---WDIKKYDKF---------GSKEFAAVALQAAEESEVLLKNDGNILP 408 >2B3Z-A nrPDB Length = 373 Score = 30.4 bits (67), Expect = 0.98, Method: Compositional matrix adjust. Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%) Query: 193 GKTGDAAQIVIGAGIN---MAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAA 249 GKT A+++I +GI +AMR V +G ++EAGI + LA R L Sbjct: 90 GKTPPCAELIINSGIKRVFVAMRDPNPLVAGRGISMMKEAGIEVREGILADQAER-LNEK 148 Query: 250 LELFEQEGLAPYLS 263 F + GL PY++ Sbjct: 149 FLHFMRTGL-PYVT 161 >1JX7-A nrPDB Length = 117 Score = 28.5 bits (62), Expect = 4.1, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 26/40 (65%), Gaps = 5/40 (12%) Query: 54 PGKGYSLPEPIQLLNAKQILGQL-----DGGSVAVLPVID 88 PG+GY++ + +++L A+ + +L DG ++ LP+ID Sbjct: 55 PGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLID 94 >1JPH-A nrPDB Length = 388 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 11/19 (57%), Positives = 15/19 (78%) Query: 47 GVDVFTVPGKGYSLPEPIQ 65 G++V VPGKG S PEP++ Sbjct: 116 GMEVTMVPGKGPSFPEPLR 134 >1CD1-A nrPDB Length = 315 Score = 27.7 bits (60), Expect = 6.3, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 17/29 (58%) Query: 43 LRDWGVDVFTVPGKGYSLPEPIQLLNAKQ 71 +R WG TVPG L PI++LNA Q Sbjct: 123 VRFWGTSWQTVPGAPSWLDLPIKVLNADQ 151 >4V83-BQ nrPDB Length = 116 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 21/34 (61%) Query: 226 LQEAGINLDRNTLAAMLIRELRAALELFEQEGLA 259 L++AGI +DR LA + +RE + EL E+ A Sbjct: 81 LKKAGIEVDRKNLADLAVREPQVFAELVERAKAA 114 >2Y4O-A nrPDB Length = 443 Score = 27.3 bits (59), Expect = 9.0, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 10/78 (12%) Query: 188 LVELTGKTGDAAQIVIGAGINMAMRRVEESVV------NQGWITLQEAGINLDRNTLAAM 241 L ++TG++ D ++I G+N+ ++EE VV Q ITL G ++DR LA Sbjct: 327 LAKITGRSDD---MLIVRGVNVFPSQIEEIVVALPLLSGQFQITLSRDG-HMDRLDLAVE 382 Query: 242 LIRELRAALELFEQEGLA 259 L E A++ E+ LA Sbjct: 383 LRSEAAASVTDGERAALA 400 >5HCE-A nrPDB Length = 998 Score = 27.3 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 43/81 (53%), Gaps = 7/81 (8%) Query: 215 EESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALEL---FEQEGLAPYLSRWEKLD-N 270 EE G+ + Q+ ++ T ++L+++LR ++++ ++ +G L ++ D N Sbjct: 598 EEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGA---LHNYKMTDKN 654 Query: 271 FINRPVKLIIGDKEIFGISRG 291 F+ RPV++++ D I G Sbjct: 655 FLGRPVEVLLNDDLIVSTGFG 675 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2EWN-A nrPDB 423 e-119 3V7C-A nrPDB 344 3e-95 2EJ9-A nrPDB 217 4e-57 4XU2-A nrPDB 203 1e-52 2FYK-A nrPDB 197 7e-51 3FJP-A nrPDB 194 6e-50 6CK0-A nrPDB 131 3e-31 Sequences not found previously or not previously below threshold: 5KZW-A nrPDB 31 0.86 5T8U-A nrPDB 30 1.1 5TH7-A nrPDB 30 1.4 2O0B-A nrPDB 30 1.8 6C43-A nrPDB 29 2.5 4N0B-A nrPDB 28 4.5 1J5Y-A nrPDB 28 4.6 1R85-A nrPDB 28 5.5 5VO2-A nrPDB 28 6.4 5EVM-A nrPDB 28 6.4 1MM8-A nrPDB 28 6.5 4P8I-A nrPDB 27 8.6 CONVERGED! >2EWN-A nrPDB Length = 321 Score = 423 bits (1087), Expect = e-119, Method: Composition-based stats. Identities = 321/321 (100%), Positives = 321/321 (100%) Query: 1 MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL 60 MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL Sbjct: 1 MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL 60 Query: 61 PEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG 120 PEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG Sbjct: 61 PEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRG 120 Query: 121 RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ 180 RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ Sbjct: 121 RKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQ 180 Query: 181 DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA 240 DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA Sbjct: 181 DRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA 240 Query: 241 MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL 300 MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL Sbjct: 241 MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLL 300 Query: 301 EQDGIIKPWMGGEISLRSAEK 321 EQDGIIKPWMGGEISLRSAEK Sbjct: 301 EQDGIIKPWMGGEISLRSAEK 321 >3V7C-A nrPDB Length = 329 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 75/302 (24%), Positives = 131/302 (43%), Gaps = 9/302 (2%) Query: 21 SGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGS 80 SG+ + E+L +SR A+ K I L+ G + +V KG+ L + + + I+ Q S Sbjct: 21 SGQSIAESLNISRTAVKKVIDQLKLEGCKIDSVNHKGHLLQQLPDIW-YQGIIDQYTKSS 79 Query: 81 V-----AVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSM 135 V IDST + +S +++ Q GRGR R W S G L++S+ Sbjct: 80 ALFDFSEVYDSIDSTQLAAKKSLVGNQSSFFILSDEQTKGRGRFNRHWSSSKGQGLWMSV 139 Query: 136 FWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKT 195 R + +L I + + + ++ D+V+VKWPND+Y+ + K+ G L E+ Sbjct: 140 VLRPNVAFSMISKFNLFIALGIRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANN 199 Query: 196 GDAAQIVIGAGINMAMR--RVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELF 253 I+ G GIN+ + +ES+ ++ LDR L++E+ F Sbjct: 200 DGIEAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLDRYQFLERLLQEIEKRYNQF 259 Query: 254 EQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQD-GIIKPWMGG 312 + + N NR + DK+ G + +D G L++ + G + Sbjct: 260 LTLPFSEIREEYIAASNIWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEAGESHRLISA 319 Query: 313 EI 314 +I Sbjct: 320 DI 321 >2EJ9-A nrPDB Length = 237 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 69/241 (28%), Positives = 115/241 (47%), Gaps = 16/241 (6%) Query: 84 LPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGP 143 L IDSTN Y + E K +A+ Q G+GR GR W+S G LY SM + Sbjct: 6 LSEIDSTNDYAKELAKEGKRNFIVLADKQNNGKGRWGRVWYSDEGG-LYFSMVL--DSKL 62 Query: 144 AAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYL----QDRKLAGILVELTGKTGDAA 199 ++L++ I + EVL+ ++ +K+PND+ + +KL GIL ELT Sbjct: 63 YNPKVINLLVPICIIEVLKNYVDKELGLKFPNDIMVKVNDNYKKLGGILTELTD-----D 117 Query: 200 QIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLA 259 ++IG GIN+ + E + + G LD+ + + ++ + LE + + + Sbjct: 118 YMIIGIGINVNNQIRNE-IREIAISLKEITGKELDKVEILSNFLKTFESYLEKLKNKEID 176 Query: 260 PY--LSRWEKLDNFINRPVKLIIGDKEIF-GISRGIDKQGALLLEQDGIIKPWMGGEISL 316 Y L +++K I + VK+++ + EI G ID G +L + GI + G I + Sbjct: 177 DYEILKKYKKYSITIGKQVKILLSNNEIITGKVYDIDFDGIVLGTEKGIERIPSGICIHV 236 Query: 317 R 317 R Sbjct: 237 R 237 >4XU2-A nrPDB Length = 270 Score = 203 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 87/263 (33%), Positives = 129/263 (49%), Gaps = 25/263 (9%) Query: 65 QLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRI--GELKSGDACIAEYQQAGRGRRGRK 122 QL+ A QLD V+ STN LL R G G IAE+Q AGRGR GR Sbjct: 23 QLIGAGSGWRQLD-----VVAQTGSTNADLLARAASGADIDGVVLIAEHQTAGRGRHGRG 77 Query: 123 WFSPFGANLYLSMFWRLEQGPAAAIG-LSLVIGIVMAEVLRKLGA---DKVRVKWPNDLY 178 W + A + LS+ R+ P A G LSL G+ + + + L A + +KWPND+ Sbjct: 78 WAATARAQIILSVGVRVVDVPVQAWGWLSLAAGLAVLDSVAPLIAVPPAETGLKWPNDVL 137 Query: 179 LQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINL-DRNT 237 + KLAGIL E+ +V+G G+N+ E V+ +L + G+ DRN Sbjct: 138 ARGGKLAGILAEVAQPF-----VVLGVGLNVTQAPEE---VDPDATSLLDLGVAAPDRNR 189 Query: 238 LAAMLIRELRAALELFEQEGLAPYLSRWEKLDNF-INRPVKL-IIGDKEIFGISRGIDKQ 295 +A+ L+REL A + + P L+ + + I V++ + G +++ GI+R ID Q Sbjct: 190 IASRLLRELEA--RIIQWRNANPQLAADYRARSLTIGSRVRVELPGGQDVVGIARDIDDQ 247 Query: 296 GALLLEQDGIIKPWMGGE-ISLR 317 G L L+ G G+ + LR Sbjct: 248 GRLCLDVGGRTVVVSAGDVVHLR 270 >2FYK-A nrPDB Length = 235 Score = 197 bits (500), Expect = 7e-51, Method: Composition-based stats. Identities = 77/244 (31%), Positives = 110/244 (45%), Gaps = 24/244 (9%) Query: 78 GGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFW 137 G V I STN++ L+ G +A+ Q G GR RKW SP G L+LS+ Sbjct: 10 GRRVIYFQEITSTNEFAK--TSYLEEGTVIVADKQTMGHGRLNRKWESPEGG-LWLSIVL 66 Query: 138 RL--EQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKT 195 Q I +G+V E L++ D R+KWPND+ + +K+AG+LVE Sbjct: 67 SPKVPQKDLPKIVFLGAVGVV--ETLKEFSIDG-RIKWPNDVLVNYKKIAGVLVE----- 118 Query: 196 GDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIREL-RAALELFE 254 G +IV+G G+N+ V N E G + ++ LI L R L + Sbjct: 119 GKGDKIVLGIGLNV-----NNKVPNGATSMKLELGSEVPLLSVFRSLITNLDRLYLNFLK 173 Query: 255 QEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQD-GIIKPWMGGE 313 L R DN I I+GD GI+ ID G L++ D G +K + G+ Sbjct: 174 NPMDILNLVR----DNMILGVRVKILGDGSFEGIAEDIDDFGRLIIRLDSGEVKKVIYGD 229 Query: 314 ISLR 317 +SLR Sbjct: 230 VSLR 233 >3FJP-A nrPDB Length = 233 Score = 194 bits (492), Expect = 6e-50, Method: Composition-based stats. Identities = 68/237 (28%), Positives = 124/237 (52%), Gaps = 12/237 (5%) Query: 84 LPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGP 143 L +DST + L + + G A +A+ Q GRGR GRKW S G LY S ++ Sbjct: 8 LKEVDSTQERLKE--WNVSYGTALVADRQTKGRGRLGRKWLSQEGG-LYFSFLLNPKEFE 64 Query: 144 AAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVI 203 ++ V +E L ++ +KWPND+Y Q++K++G+L EL+ ++++ Sbjct: 65 NLLQLPLVLGLSV-SEALEEITEIPFSLKWPNDVYFQEKKVSGVLRELS-----KDKLIV 118 Query: 204 GAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLS 263 G GIN+ R + E + ++ + G + DR + +++ + L+ F+++ + Sbjct: 119 GIGINVNQREIPEEIKDRATTLYEITGKDWDRKEVLLKVLKRISENLKKFKEKSFKEFKG 178 Query: 264 RWEKLDNFINRPVKLIIGDKEIFGISRGI-DKQGALLLEQDGIIKPWMGGEISLRSA 319 + E ++ VK ++G+ +I G G+ +K GAL+L ++G IK + GE SLR + Sbjct: 179 KIESKMLYLGEEVK-LLGEGKITGKLVGLSEKGGALILTEEG-IKEILSGEFSLRRS 233 >6CK0-A nrPDB Length = 220 Score = 131 bits (330), Expect = 3e-31, Method: Composition-based stats. Identities = 56/222 (25%), Positives = 91/222 (40%), Gaps = 32/222 (14%) Query: 83 VLPVIDSTNQYLLDRI--GELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLE 140 V + ST YLL+++ ELK+ +A+ Q G G RG W A L S+ Sbjct: 16 VFDSLPSTQTYLLEKLKNNELKAPILIVAKNQSTGIGSRGNIWEGTKSA-LTFSLALNAS 74 Query: 141 QGPA--AAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDA 198 P +L +G + EVL++LG+ + +KWPNDLYL D+K+ G+LV + Sbjct: 75 DLPKDLPMQANALYLGFLFKEVLKELGS-QTWLKWPNDLYLGDQKIGGVLVNVY-----K 128 Query: 199 AQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAAL---ELFEQ 255 V G G+N ++ + G + D + ++++ L E+ + Sbjct: 129 GMRVCGIGVNRVSKKW----------ACLDIGASDDL--IIEGFLKKIEENLFWGEVLSK 176 Query: 256 EGLAPYLSRWEKLDNFINRPVKL----IIGDKE--IFGISRG 291 L + S N V L ++ D I G Sbjct: 177 YALEFHRSNSFSFHNDWGELVSLKDAELLEDGRICIKGKIYD 218 >5KZW-A nrPDB Length = 874 Score = 30.9 bits (68), Expect = 0.86, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 106 ACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLG 165 I+ AG GR W +++ S P L + +V A+V LG Sbjct: 518 FVISRSTFAGHGRYAGHWT----GDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLG 573 Query: 166 --ADKVRVKW 173 ++++ V+W Sbjct: 574 NTSEELCVRW 583 >5T8U-A nrPDB Length = 360 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 42/118 (35%), Gaps = 11/118 (9%) Query: 155 IVMAEVLRKLGADKVRVKWPNDLYLQDRKLAG-ILVELTGKTGDAAQIVIGAGINMAMRR 213 +++ L+ + + + ND+ + D+K +G ++ I+I N+ + Sbjct: 122 LIILNTLKNHFNIEAKTQGRNDITVNDQKCSGSAFKKIKDVFLHHGTILINLEKNILNKY 181 Query: 214 VEE----------SVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPY 261 + S VN I L E N+ L LI+E E + P Sbjct: 182 LTPDKIKYIKHGVSSVNARTINLSEINNNITCENLCIALIKEFTKFYEQNYNTNIIPN 239 >5TH7-A nrPDB Length = 148 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 37/109 (33%), Gaps = 9/109 (8%) Query: 22 GEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQ------LLNAKQILGQ 75 G+ E R I++ I++ ++ G+ + + GKG + Q ++ L + Sbjct: 1 GKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIE 60 Query: 76 LD--GGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRK 122 + A+ ST Y+ L A + GR Sbjct: 61 ITDAKKREALYAQDPSTGCYMY-YFQYLSKTYCVDATRETNRLGRLINH 108 >2O0B-A nrPDB Length = 450 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 19/46 (41%), Gaps = 4/46 (8%) Query: 33 RAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLL----NAKQILG 74 R A+ I LR GV+V + +LPE +L Q G Sbjct: 385 RMAMAGAIIGLRVAGVEVDDIAATTKTLPEFPRLWAEMVGPGQGWG 430 >6C43-A nrPDB Length = 477 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 24/138 (17%), Positives = 41/138 (29%), Gaps = 9/138 (6%) Query: 46 WGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVI-------DSTNQYLLDRI 98 GV F G ++ + I L + + +ST L + Sbjct: 269 QGVRTFGFYNAGQDCTAACRIYAQRGIYDALVEKLGNAVSSLKMGAPEDESTELGPLSSL 328 Query: 99 GELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMA 158 LK A + E + R G Y + + AI V G V++ Sbjct: 329 AHLKRVTAAVEEAKALSHIRVITGGSQTEGKGYYFAPTLLADAKQEDAIVQREVFGPVVS 388 Query: 159 EVLRKLGADKVRVKWPND 176 + + ++W ND Sbjct: 389 ITV--FDDEDQVLRWAND 404 >4N0B-A nrPDB Length = 479 Score = 28.2 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 13 LLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEP 63 LL + + S +L E L +S ++N Q L G ++ + KG+ + E Sbjct: 33 LLPHSKVPSKRELAENLKVSVNSVNSAYQQLLAEGY-LYAIERKGFFVEEL 82 >1J5Y-A nrPDB Length = 187 Score = 28.2 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 21 SGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSL 60 SG QL E L +SR I + I LR G ++ P +GY L Sbjct: 38 SGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATP-RGYVL 76 >1R85-A nrPDB Length = 379 Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 9/61 (14%), Positives = 25/61 (40%), Gaps = 9/61 (14%) Query: 33 RAAINKHIQTLRDWGVDVFTVPGKGYS---------LPEPIQLLNAKQILGQLDGGSVAV 83 R A+ ++ L++ GV + + + + + + I + A + Q+ V++ Sbjct: 211 RTALYNLVKQLKEEGVPIDGIGHQSHIQIGWPSEAEIEKTINMFAALGLDNQITELDVSM 270 Query: 84 L 84 Sbjct: 271 Y 271 >5VO2-A nrPDB Length = 300 Score = 27.8 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 36/89 (40%), Gaps = 3/89 (3%) Query: 190 ELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAA 249 E+ K D++ I+ G G N V S + I L++ + RN + R++ Sbjct: 196 EIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPS---FRQILLH 252 Query: 250 LELFEQEGLAPYLSRWEKLDNFINRPVKL 278 L++ + L+ + K VKL Sbjct: 253 LDIASADVLSTPQETYFKSQAEWREEVKL 281 >5EVM-A nrPDB Length = 529 Score = 27.8 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 37/98 (37%), Gaps = 2/98 (2%) Query: 184 LAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLI 243 L +++ L G G I + + + +Q Q + D A L+ Sbjct: 422 LGNVIISLGKYLGSVNYNSEGIAIGPPVFTDKVDISSQISSMNQSLQQSKDYIKEAQRLL 481 Query: 244 RELRAALELFEQEGLA--PYLSRWEKLDNFINRPVKLI 279 + +L+L +Q LS+ ++N I R KLI Sbjct: 482 DTVNPSLKLMKQIEDKIEEILSKIYHIENEIARIKKLI 519 >1MM8-A nrPDB Length = 481 Score = 27.8 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 18/105 (17%) Query: 63 PIQLLNAKQILGQ------------LDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIA- 109 P Q L A+ +L + L +L +D + ++ G L+ IA Sbjct: 376 PPQALRAQGLLKEAEHVESQSAETVLTPDECQLLGYLDKGKRKRKEKAGSLQWAYMAIAR 435 Query: 110 -----EYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGL 149 + ++ G G W L F + A I + Sbjct: 436 LGGFMDSKRTGIASWGALWEGWEALQSKLDGFLAAKDLMAQGIKI 480 >4P8I-A nrPDB Length = 260 Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 19/52 (36%), Gaps = 6/52 (11%) Query: 253 FEQEGLAPYLSRWEKLDNFINRPVKL------IIGDKEIFGISRGIDKQGAL 298 F+ P ++W + + K I+ K+I K+GAL Sbjct: 172 FKNPEFDPQKAQWRGENVILLGEDKYFAHGLGILNGKQIIDKLNSFRKKGAL 223 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.128 0.308 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,219,809 Number of Sequences: 36641 Number of extensions: 369955 Number of successful extensions: 1234 Number of sequences better than 10.0: 22 Number of HSP's better than 10.0 without gapping: 26 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1168 Number of HSP's gapped (non-prelim): 47 length of query: 321 length of database: 10,336,785 effective HSP length: 97 effective length of query: 224 effective length of database: 6,782,608 effective search space: 1519304192 effective search space used: 1519304192 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 59 (27.4 bits)