BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P06281 (402 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5MKT-A nrPDB 784 0.0 5MLG-A nrPDB 665 0.0 1SMR-A nrPDB 651 0.0 4AMT-A nrPDB 566 e-162 3VCM-A nrPDB 513 e-146 5UX4-A nrPDB 342 1e-94 1TZS-A nrPDB 298 4e-81 5NFG-A nrPDB 286 1e-77 2PSG-A nrPDB 285 2e-77 4PEP-A nrPDB 281 3e-76 5N71-A nrPDB 276 1e-74 3OAD-B nrPDB 265 2e-71 1PSO-E nrPDB 265 3e-71 1AM5-A nrPDB 258 2e-69 3O9L-A nrPDB 256 1e-68 1FMX-A nrPDB 254 5e-68 4AA9-A nrPDB 246 1e-65 1AVF-A nrPDB 244 3e-65 4CMS-A nrPDB 239 1e-63 4OC6-B nrPDB 223 2e-58 1QDM-A nrPDB 211 4e-55 1B5F-A nrPDB 202 2e-52 3QS1-A nrPDB 189 1e-48 2ANL-A nrPDB 186 1e-47 1MIQ-A nrPDB 186 2e-47 1QS8-A nrPDB 182 2e-46 5BWY-A nrPDB 174 5e-44 2BJU-A nrPDB 174 5e-44 1XDH-A nrPDB 173 1e-43 5JOD-A nrPDB 171 5e-43 5I70-B nrPDB 170 8e-43 3QVI-A nrPDB 144 5e-35 3FNT-A nrPDB 142 2e-34 4OD9-A nrPDB 130 1e-30 3LIZ-A nrPDB 124 7e-29 1UH8-A nrPDB 123 1e-28 2ASI-A nrPDB 107 9e-24 1MPP-A nrPDB 103 1e-22 3ZKX-A nrPDB 102 3e-22 2QZW-A nrPDB 98 5e-21 3FV3-A nrPDB 93 2e-19 3PVK-A nrPDB 88 7e-18 1WKR-A nrPDB 88 7e-18 4Y9W-A nrPDB 86 2e-17 2H6T-A nrPDB 85 5e-17 1J71-A nrPDB 83 2e-16 2QZX-A nrPDB 80 1e-15 3TPL-A nrPDB 77 2e-14 4B1C-A nrPDB 67 9e-12 1B5F-B nrPDB 67 2e-11 1PPK-E nrPDB 66 3e-11 5HCT-A nrPDB 65 4e-11 3PI0-A nrPDB 64 1e-10 1IZE-A nrPDB 55 5e-08 1IBQ-A nrPDB 55 6e-08 4ZL4-A nrPDB 48 7e-06 3EMY-A nrPDB 43 2e-04 2QAE-A nrPDB 30 1.8 3RRA-A nrPDB 29 3.1 3UVA-A nrPDB 28 6.5 >5MKT-A nrPDB Length = 389 Score = 784 bits (2024), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/381 (100%), Positives = 381/381 (100%) Query: 22 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 81 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN Sbjct: 1 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 60 Query: 82 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 141 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS Sbjct: 61 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 120 Query: 142 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 201 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV Sbjct: 121 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 180 Query: 202 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS 261 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS Sbjct: 181 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS 240 Query: 262 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC 321 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC Sbjct: 241 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC 300 Query: 322 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF 381 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF Sbjct: 301 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF 360 Query: 382 IRKFYTEFDRHNNRIGFALAR 402 IRKFYTEFDRHNNRIGFALAR Sbjct: 361 IRKFYTEFDRHNNRIGFALAR 381 >5MLG-A nrPDB Length = 389 Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/381 (84%), Positives = 342/381 (89%) Query: 22 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 81 LPT TA+F RI LKKMPSVREILEERGVDMTR+SAEWG F K+ S TN+TSPVVLTNYL+ Sbjct: 1 LPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGEFIKKSSFTNVTSPVVLTNYLD 60 Query: 82 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 141 TQYYGEIGIGTP QTFKVIFDTGSANLWVPSTKC LY AC IH+LY+SS+SSSYMENG+ Sbjct: 61 TQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYMENGT 120 Query: 142 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 201 +FTIHYGSG+VKGFLSQD VTVGGI VTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV Sbjct: 121 EFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 180 Query: 202 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS 261 GV PVFDHILSQ VLKEEVFSVYY+R SHLLGGEVVLGGSDPQHYQGNFHYVSISK S Sbjct: 181 DGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLGGSDPQHYQGNFHYVSISKAGS 240 Query: 262 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC 321 WQITMKGVSVG +TLLCEEGC VVDTG+S+IS PTSSL+LIMQALG KEKR YVVNC Sbjct: 241 WQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVNC 300 Query: 322 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF 381 SQVPTLPDISF LGGR YTLS+ DYV + P R D LC LAL +DIPPPTGPVWVLGATF Sbjct: 301 SQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPPPTGPVWVLGATF 360 Query: 382 IRKFYTEFDRHNNRIGFALAR 402 IRKFYTEFDRHNNRIGFALAR Sbjct: 361 IRKFYTEFDRHNNRIGFALAR 381 >1SMR-A nrPDB Length = 335 Score = 651 bits (1680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/335 (95%), Positives = 330/335 (98%) Query: 68 TNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSL 127 T+L SPVVLTNYLN+QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSL Sbjct: 1 TDLISPVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSL 60 Query: 128 YESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAK 187 YESSDSSSYMENG DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVT+LPLIPFMLA+ Sbjct: 61 YESSDSSSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTQLPLIPFMLAQ 120 Query: 188 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHY 247 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKE+VFSVYYNRG HLLGGEVVLGGSDPQHY Sbjct: 121 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHLLGGEVVLGGSDPQHY 180 Query: 248 QGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQAL 307 QG+FHYVS+SKTDSWQITMKGVSVGSSTLLCEEGC VVVDTGSSFISAPTSSLKLIMQAL Sbjct: 181 QGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQAL 240 Query: 308 GAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDI 367 GAKEKR+ EYVV+CSQVPTLPDISF+LGGRAYTLSSTDYVLQYPNRRDKLCT+ALHAMDI Sbjct: 241 GAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDI 300 Query: 368 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR Sbjct: 301 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 335 >4AMT-A nrPDB Length = 383 Score = 566 bits (1459), Expect = e-162, Method: Compositional matrix adjust. Identities = 269/384 (70%), Positives = 319/384 (83%), Gaps = 4/384 (1%) Query: 22 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 81 LPT T TF+RI LK+MPS+RE L+ERGVDM RL EW KR +L N TS V+LTNY++ Sbjct: 1 LPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMD 60 Query: 82 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 141 TQYYGEIGIGTPPQTFKV+FDTGS+N+WVPS+KCSRLY AC H L+++SDSSSY NG+ Sbjct: 61 TQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGT 120 Query: 142 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 201 + T+ Y +G V GFLSQD +TVGGITVTQ FGEVTE+P +PFMLA+FDGV+GMGF QA+ Sbjct: 121 ELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAI 180 Query: 202 GGVTPVFDHILSQGVLKEEVFSVYYNR---GSHLLGGEVVLGGSDPQHYQGNFHYVSISK 258 G VTP+FD+I+SQGVLKE+VFS YYNR S LGG++VLGGSDPQHY+GNFHY+++ K Sbjct: 181 GRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 240 Query: 259 TDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYV 318 T WQI MKGVSVGSSTLLCE+GC +VDTG+S+IS TSS++ +M+ALGAK KR+ +YV Sbjct: 241 TGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAK-KRLFDYV 299 Query: 319 VNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLG 378 V C++ PTLPDISF LGG+ YTL+S DYV Q KLCTLA+HAMDIPPPTGP W LG Sbjct: 300 VKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALG 359 Query: 379 ATFIRKFYTEFDRHNNRIGFALAR 402 ATFIRKFYTEFDR NNRIGFALAR Sbjct: 360 ATFIRKFYTEFDRRNNRIGFALAR 383 >3VCM-A nrPDB Length = 335 Score = 513 bits (1320), Expect = e-146, Method: Compositional matrix adjust. Identities = 241/337 (71%), Positives = 287/337 (85%), Gaps = 3/337 (0%) Query: 66 SLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIH 125 +L N TS V+LTNY++TQYYGEIGIGTPPQTFKV+FDTGS+N+WVPS+KCSRLY AC H Sbjct: 2 TLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYH 61 Query: 126 SLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFML 185 L+++SDSSSY NG++ T+ Y +G V GFLSQD +TVGGITVTQ FGEVTE+P +PFML Sbjct: 62 KLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFML 121 Query: 186 AKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQ 245 A+FDGV+GMGF QA+G VTP+FD+I+SQGVLKE+VFS YYNR S LGG++VLGGSDPQ Sbjct: 122 AEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDS--LGGQIVLGGSDPQ 179 Query: 246 HYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQ 305 HY+GNFHY+++ KT WQI MKGVSVGSSTLLCE+GC +VDTG+S+IS TSS++ +M+ Sbjct: 180 HYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLME 239 Query: 306 ALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAM 365 ALGAK KR+ +YVV C++ PTLPDISF LGG+ YTL+S DYV Q KLCTLA+HAM Sbjct: 240 ALGAK-KRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAM 298 Query: 366 DIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 DIPPPTGP W LGATFIRKFYTEFDR NNRIGFALAR Sbjct: 299 DIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 335 >5UX4-A nrPDB Length = 420 Score = 342 bits (878), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 179/405 (44%), Positives = 252/405 (62%), Gaps = 16/405 (3%) Query: 9 WALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTK--RPS 66 W+ + L+ S+ T + RIPL+K S+R + E G + L + G TK S Sbjct: 3 WSWVFLF---FLSVTTGVHSLIRIPLRKFTSIRRTMTEVGGSVEDLILK-GPITKYSMQS 58 Query: 67 LTNLTSPV--VLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGI 124 PV +L NYL+ QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC + Sbjct: 59 SPRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWV 118 Query: 125 HSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTV------GGITV-TQTFGEVTE 177 H Y S SS+Y++NG+ F IHYGSG + G+LSQD+V+V GGI V Q FGE T+ Sbjct: 119 HHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATK 178 Query: 178 LPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRG-SHLLGGE 236 P + F+ AKFDG+LGMG+P +V V PVFD+++ Q ++++ +FS Y NR + GGE Sbjct: 179 QPGVVFIAAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGE 238 Query: 237 VVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAP 296 ++LGG+D ++Y G Y+++++ WQ+ M + VGS LC+ GC +VDTG+S + P Sbjct: 239 LMLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGP 298 Query: 297 TSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDK 356 +K + +A+GA EY++ C +V +LP I+F LGG+ Y L Y+L+ Sbjct: 299 VDEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKT 358 Query: 357 LCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 +C MDIPPP+GP+W+LG FI +YT FDR NR+GFA A Sbjct: 359 ICLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 403 >1TZS-A nrPDB Length = 351 Score = 298 bits (762), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 145/328 (44%), Positives = 208/328 (63%), Gaps = 5/328 (1%) Query: 76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 135 L NYL+ +Y+G I IG+PPQ F VIFDTGS+NLWVPS C+ AC HS ++ S SS+ Sbjct: 17 LINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSP--ACKTHSRFQPSQSST 74 Query: 136 YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGM 194 Y + G F+I YG+G + G + D V+V G+TV Q FGE P F+ A+FDG+LG+ Sbjct: 75 YSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGL 134 Query: 195 GFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHL-LGGEVVLGGSDPQHYQGNFHY 253 G+P+ AVGGVTPVFD++++Q ++ +FSVY + G E++ GG D H+ G+ ++ Sbjct: 135 GYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNW 194 Query: 254 VSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKR 313 V ++K WQI + + VG + + C EGC +VDTG+S I+ P+ +K + A+GA Sbjct: 195 VPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD 254 Query: 314 IEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGP 373 EY V C+ + +PD++F + G YTLS T Y L + C+ +DI PP GP Sbjct: 255 -GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGP 313 Query: 374 VWVLGATFIRKFYTEFDRHNNRIGFALA 401 +W+LG FIR+FY+ FDR NNR+G A A Sbjct: 314 LWILGDVFIRQFYSVFDRGNNRVGLAPA 341 >5NFG-A nrPDB Length = 383 Score = 286 bits (732), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 160/377 (42%), Positives = 227/377 (60%), Gaps = 9/377 (2%) Query: 31 RIPLKKMPSVR-EILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVV-LTNYLNTQYYGEI 88 R+ LKK R + L GV M L F R +L + S +V LTN +T YYGEI Sbjct: 9 RVGLKKRKVDRLDQLRAHGVHM--LGNARKDFGFRRTLRDSGSGIVALTNDRDTAYYGEI 66 Query: 89 GIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYG 148 GIGTPPQ F VIFDTGS++LWVPSTKC LAC IH Y+S DSS+Y NG+ +I YG Sbjct: 67 GIGTPPQNFAVIFDTGSSDLWVPSTKCD-TSLACVIHPRYDSGDSSTYKGNGTTASIQYG 125 Query: 149 SGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPV 207 +G + GF SQDSV VG + V Q F E TE F+ ++FDG+LG+GF + G PV Sbjct: 126 TGAIVGFYSQDSVEVGDLVVEHQDFIETTEEDDTVFLKSEFDGILGLGFQEISAGKAVPV 185 Query: 208 FDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITM 266 + ++++QG+++E VFS + NR GGE+V GG DP H++GN YV +++ WQ M Sbjct: 186 WYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNHFRGNHTYVPVTRKGYWQFEM 245 Query: 267 KGVSVGS-STLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK-EKRIEEYVVNCSQV 324 V +G S+ C GCA + D+G+SF + PT+ + I QA+GAK E +V+C+ + Sbjct: 246 GDVLIGDKSSGFCAGGCAAIADSGTSFFAGPTAIITQINQAIGAKGGGGSAESIVDCNGI 305 Query: 325 PTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRK 384 ++P+I+F +G + + ++ Y+ + C A+DI P GP+W+LG F+ Sbjct: 306 SSMPNIAFTIGSKLFEVTPEQYIYKVGEGEAATCISGFTALDIMSPQGPIWILGDMFMGP 365 Query: 385 FYTEFDRHNNRIGFALA 401 ++T FD R+GFA A Sbjct: 366 YHTVFDYGKLRVGFAEA 382 >2PSG-A nrPDB Length = 370 Score = 285 bits (730), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 150/372 (40%), Positives = 217/372 (58%), Gaps = 10/372 (2%) Query: 31 RIPLKKMPSVREILEERGV--DMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYGEI 88 ++PL + S+R+ L + G D + P L L NYL+T+Y+G I Sbjct: 3 KVPLVRKKSLRQNLIKDGKLKDFLKTHKHNPASKYFPEAAALIGDEPLENYLDTEYFGTI 62 Query: 89 GIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYG 148 GIGTP Q F VIFDTGS+NLWVPS CS L AC H+ + DSS++ + +I YG Sbjct: 63 GIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNPDDSSTFEATSQELSITYG 120 Query: 149 SGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPV 207 +G + G L D+V VGGI+ T Q FG P A FDG+LG+ +P+ + G TPV Sbjct: 121 TGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGATPV 180 Query: 208 FDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMK 267 FD++ QG++ +++FSVY + G V+LGG D +Y G+ ++V +S WQIT+ Sbjct: 181 FDNLWDQGLVSQDLFSVYLSSNDDS-GSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLD 239 Query: 268 GVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTL 327 +++ T+ C GC +VDTG+S ++ PTS++ I +GA E E V++CS + +L Sbjct: 240 SITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSIDSL 299 Query: 328 PDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYT 387 PDI F + G Y LS + Y+LQ D CT MD+P +G +W+LG FIR++YT Sbjct: 300 PDIVFTIDGVQYPLSPSAYILQ----DDDSCTSGFEGMDVPTSSGELWILGDVFIRQYYT 355 Query: 388 EFDRHNNRIGFA 399 FDR NN++G A Sbjct: 356 VFDRANNKVGLA 367 >4PEP-A nrPDB Length = 326 Score = 281 bits (720), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 141/325 (43%), Positives = 201/325 (61%), Gaps = 8/325 (2%) Query: 76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 135 L NYL+T+Y+G IGIGTP Q F VIFDTGS+NLWVPS CS L AC H+ + DSS+ Sbjct: 6 LENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNPDDSST 63 Query: 136 YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGM 194 + + +I YG+G + G L D+V VGGI+ T Q FG P A FDG+LG+ Sbjct: 64 FEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGL 123 Query: 195 GFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYV 254 +P+ + G TPVFD++ QG++ +++FSVY + G V+LGG D +Y G+ ++V Sbjct: 124 AYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDS-GSVVLLGGIDSSYYTGSLNWV 182 Query: 255 SISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRI 314 +S WQIT+ +++ T+ C GC +VDTG+S ++ PTS++ I +GA E Sbjct: 183 PVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSD 242 Query: 315 EEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPV 374 E V++CS + +LPDI F + G Y LS + Y+LQ D CT MD+P +G + Sbjct: 243 GEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQ----DDDSCTSGFEGMDVPTSSGEL 298 Query: 375 WVLGATFIRKFYTEFDRHNNRIGFA 399 W+LG FIR++YT FDR NN++G A Sbjct: 299 WILGDVFIRQYYTVFDRANNKVGLA 323 >5N71-A nrPDB Length = 345 Score = 276 bits (705), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 143/335 (42%), Positives = 210/335 (62%), Gaps = 13/335 (3%) Query: 73 PVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSD 132 P L N L+ YYG I IGTPPQ F+VIFDTGSANLW+PS+KC+ Y C H Y+SS Sbjct: 7 PEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTKY--CLHHHRYDSSK 64 Query: 133 SSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGV 191 SS+Y +G +FTI YGSG V+GF+S+D +G V+ Q GE + + A FDG+ Sbjct: 65 SSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKVSGQPLGEALVVGGESLLEAPFDGI 124 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVLKEE-VFSVYYNRG-SHLLGGEVVLGGSDPQHYQG 249 LG+ +P+ AV GV PVFD+++ QG+L E+ VFSVY NR S GGEV+ GG D HY+G Sbjct: 125 LGLAYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKG 184 Query: 250 NFHYVSISKTDSWQITMKGVSVGSST-----LLCEEGCAVVVDTGSSFISAPTSSLKLIM 304 + YV ++ WQ + GV S++ LLC++GC + +TG+S I+ P + + Sbjct: 185 SITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGPPEEVDSLN 244 Query: 305 QALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHA 364 Q LG + +Y+++C ++ +LP+++F + G+ ++L S DYVL+ + LC Sbjct: 245 QYLGGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVSGFMG 304 Query: 365 MDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399 +++P P+W+LG F+ +YT FDR +R+GFA Sbjct: 305 LEMPQ---PLWILGDVFLGPYYTIFDRDQDRVGFA 336 >3OAD-B nrPDB Length = 176 Score = 265 bits (677), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 123/170 (72%), Positives = 144/170 (84%), Gaps = 1/170 (0%) Query: 233 LGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSF 292 LGG++VLGGSDPQHY+GNFHY+++ KT WQI MKGVSVGSSTLLCE+GC +VDTG+S+ Sbjct: 2 LGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASY 61 Query: 293 ISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPN 352 IS TSS++ +M+ALGAK KR+ +YVV C++ PTLPDISF LGG+ YTL+S DYV Q Sbjct: 62 ISGSTSSIEKLMEALGAK-KRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESY 120 Query: 353 RRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 KLCTLA+HAMDIPPPTGP W LGATFIRKFYTEFDR NNRIGFALAR Sbjct: 121 SSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 170 >1PSO-E nrPDB Length = 326 Score = 265 bits (676), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 133/325 (40%), Positives = 196/325 (60%), Gaps = 8/325 (2%) Query: 76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 135 L NYL+ +Y+G IGIGTP Q F V+FDTGS+NLWVPS CS L AC H+ + DSS+ Sbjct: 6 LENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSL--ACTNHNRFNPEDSST 63 Query: 136 YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGM 194 Y +I YG+G + G L D+V VGGI+ T Q FG P A FDG+LG+ Sbjct: 64 YQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGL 123 Query: 195 GFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYV 254 +P+ + G TPVFD+I +QG++ +++FSVY + G V+ GG D +Y G+ ++V Sbjct: 124 AYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQS-GSVVIFGGIDSSYYTGSLNWV 182 Query: 255 SISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRI 314 ++ WQIT+ +++ + C EGC +VDTG+S ++ PTS + I +GA E Sbjct: 183 PVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSD 242 Query: 315 EEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPV 374 + VV+CS + +LPDI F + G Y + + Y+LQ + C M++P +G + Sbjct: 243 GDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPTESGEL 298 Query: 375 WVLGATFIRKFYTEFDRHNNRIGFA 399 W+LG FIR+++T FDR NN++G A Sbjct: 299 WILGDVFIRQYFTVFDRANNQVGLA 323 >1AM5-A nrPDB Length = 324 Score = 258 bits (660), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 137/328 (41%), Positives = 201/328 (61%), Gaps = 12/328 (3%) Query: 76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 135 + N +T+YYG I IGTPP++FKVIFDTGS+NLWV S+ CS AC H+ ++ SS+ Sbjct: 6 MKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCSA--QACSNHNKFKPRQSST 63 Query: 136 YMENGSDFTIHYGSGRVKGFLSQDSVTVGGIT-VTQTFGEVTELPLIPFMLAK-FDGVLG 193 Y+E G + YG+G ++G L QD+V+VGG + Q GE P PF A FDG+LG Sbjct: 64 YVETGKTVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTEPG-PFQAAAPFDGILG 122 Query: 194 MGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHY 253 + +P+ A G PVFD++ SQ ++++++FS +Y G G EV+LGG D HY G+ H+ Sbjct: 123 LAYPSIAAAGAVPVFDNMGSQSLVEKDLFS-FYLSGGGANGSEVMLGGVDNSHYTGSIHW 181 Query: 254 VSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKR 313 + ++ WQ+ + G++V T C EGC +VDTG+S I AP S+L IM+ +GA E + Sbjct: 182 IPVTAEKYWQVALDGITVNGQTAAC-EGCQAIVDTGTSKIVAPVSALANIMKDIGASENQ 240 Query: 314 IEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGP 373 E + NC+ V +LPDI+F + G L + Y+ CT L + +P T Sbjct: 241 -GEMMGNCASVQSLPDITFTINGVKQPLPPSAYI----EGDQAFCTSGLGSSGVPSNTSE 295 Query: 374 VWVLGATFIRKFYTEFDRHNNRIGFALA 401 +W+ G F+R +YT +DR NN++GFA A Sbjct: 296 LWIFGDVFLRNYYTIYDRTNNKVGFAPA 323 >3O9L-A nrPDB Length = 166 Score = 256 bits (654), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 118/165 (71%), Positives = 143/165 (86%) Query: 66 SLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIH 125 +L N TS V+LTNY++TQYYGEIGIGTPPQTFKV+FDTGS+N+WVPS+KCSRLY AC H Sbjct: 2 TLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYH 61 Query: 126 SLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFML 185 L+++SDSSSY NG++ T+ Y +G V GFLSQD +TVGGITVTQ FGEVTE+P +PFML Sbjct: 62 KLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFML 121 Query: 186 AKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGS 230 A+FDGV+GMGF QA+G VTP+FD+I+SQGVLKE+VFS YYNR S Sbjct: 122 AEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDS 166 >1FMX-A nrPDB Length = 329 Score = 254 bits (649), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 129/331 (38%), Positives = 196/331 (59%), Gaps = 10/331 (3%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 V LTNYLN QYY +I +GTPPQ FKVI DTGS+NLWVPS +C LAC +HS Y+ S Sbjct: 5 VPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGS--LACFLHSKYDHEAS 62 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVL 192 SSY NG++F I YG+G ++G++SQD++++G +T+ Q F E T P + F KFDG+L Sbjct: 63 SSYKANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTFAFGKFDGIL 122 Query: 193 GMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLL--GGEVVLGGSDPQHYQGN 250 G+G+ +V V P F + + Q +L E+ F+ Y S GGE GG D ++G+ Sbjct: 123 GLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESKFKGD 182 Query: 251 FHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK 310 ++ + + W++ +G+ +G E A +DTG+S I+ P+ ++I +GAK Sbjct: 183 ITWLPVRRKAYWEVKFEGIGLGDEYAELESHGA-AIDTGTSLITLPSGLAEMINAEIGAK 241 Query: 311 EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPP 370 + +Y ++C+ LPD+ F+ G +T+ DY L+ C A+ MD P P Sbjct: 242 KGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEVSGS----CISAITPMDFPEP 297 Query: 371 TGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 GP+ ++G F+RK+Y+ +D NN +G A A Sbjct: 298 VGPLAIVGDAFLRKYYSIYDLGNNAVGLAKA 328 >4AA9-A nrPDB Length = 320 Score = 246 bits (629), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 126/327 (38%), Positives = 192/327 (58%), Gaps = 13/327 (3%) Query: 76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 135 LT+YL++QY+G+I IGTPPQ F V+FDTGS++LWVPS C C H ++ SS+ Sbjct: 5 LTSYLDSQYFGKIYIGTPPQEFTVVFDTGSSDLWVPSIYCKSN--VCKNHHRFDPRKSST 62 Query: 136 YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGM 194 + G +IHYG+G ++GFL D+VTV I QT G TE P F ++FDG+LG+ Sbjct: 63 FRNLGKPLSIHYGTGSMEGFLGYDTVTVSNIVDPNQTVGLSTEQPGEVFTYSEFDGILGL 122 Query: 195 GFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYV 254 +P+ A PVFD+++ + ++ ++FSVY +R G + LG DP +Y G+ H+V Sbjct: 123 AYPSLASEYSVPVFDNMMDRHLVARDLFSVYMDRNGQ--GSMLTLGAIDPSYYTGSLHWV 180 Query: 255 SISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRI 314 ++ WQ T+ V++ + C GC ++DTG+S + P+S + I A+GA E R Sbjct: 181 PVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLFGPSSDILKIQMAIGATENRY 240 Query: 315 EEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPV 374 E+ VNC + ++P + F++ GR Y LS + Y ++ CT + + Sbjct: 241 GEFDVNCGNLRSMPTVVFEINGRDYPLSPS----AYTSKDQGFCTSGFQGDN----NSEL 292 Query: 375 WVLGATFIRKFYTEFDRHNNRIGFALA 401 W+LG FIR++Y+ FDR NNR+G A A Sbjct: 293 WILGDVFIREYYSVFDRANNRVGLAKA 319 >1AVF-A nrPDB Length = 329 Score = 244 bits (624), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 124/326 (38%), Positives = 188/326 (57%), Gaps = 9/326 (2%) Query: 79 YLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYME 138 Y++ Y+GEI IGTPPQ F V+FDTGS+NLWVPS C AC HS + S+SS+Y Sbjct: 9 YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQ--ACTSHSRFNPSESSTYST 66 Query: 139 NGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFP 197 NG F++ YGSG + GF D++TV I V Q FG P F+ A+FDG++G+ +P Sbjct: 67 NGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYP 126 Query: 198 AQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSIS 257 A +V T ++ +G L VFSVY + GG VV GG D Y G ++ ++ Sbjct: 127 ALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVT 186 Query: 258 KTDSWQITMKGVSV-GSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEE 316 + WQI ++ + G ++ C EGC +VDTG+S ++ P + ++QA GA+E + Sbjct: 187 QELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQ 246 Query: 317 YVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTG-PVW 375 ++VNC+ + LP ++F + G + L + Y+L + CT+ + + G P+W Sbjct: 247 FLVNCNSIQNLPSLTFIINGVEFPLPPSSYIL----SNNGYCTVGVEPTYLSSQNGQPLW 302 Query: 376 VLGATFIRKFYTEFDRHNNRIGFALA 401 +LG F+R +Y+ +D NNR+GFA A Sbjct: 303 ILGDVFLRSYYSVYDLGNNRVGFATA 328 >4CMS-A nrPDB Length = 323 Score = 239 bits (611), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 122/331 (36%), Positives = 194/331 (58%), Gaps = 13/331 (3%) Query: 72 SPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESS 131 + V LTNYL++QY+G+I +GTPPQ F V+FDTGS++ WVPS C AC H ++ Sbjct: 4 ASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCKSN--ACKNHQRFDPR 61 Query: 132 DSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGIT-VTQTFGEVTELPLIPFMLAKFDG 190 SS++ G +IHYG+G ++G L D+VTV I + QT G T+ P F A+FDG Sbjct: 62 KSSTFQNLGKPLSIHYGTGSMQGILGYDTVTVSNIVDIQQTVGLSTQEPGDVFTYAEFDG 121 Query: 191 VLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGN 250 +LGM +P+ A PVFD+++++ ++ +++FSVY +R + LG DP +Y G+ Sbjct: 122 ILGMAYPSLASEYSIPVFDNMMNRHLVAQDLFSVYMDRNGQ--ESMLTLGAIDPSYYTGS 179 Query: 251 FHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK 310 H+V ++ WQ T+ V++ + CE GC ++DTG+S + P+S + I QA+GA Sbjct: 180 LHWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDILNIQQAIGAT 239 Query: 311 EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPP 370 + + E+ ++C + +P + F++ G+ Y L+ + Y Q CT + + Sbjct: 240 QNQYGEFDIDCDNLSYMPTVVFEINGKMYPLTPSAYTSQ----DQGFCTSGFQSEN---- 291 Query: 371 TGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 W+LG FIR++Y+ FDR NN +G A A Sbjct: 292 HSQKWILGDVFIREYYSVFDRANNLVGLAKA 322 >4OC6-B nrPDB Length = 243 Score = 223 bits (567), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 104/240 (43%), Positives = 153/240 (63%), Gaps = 2/240 (0%) Query: 164 GGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVF 222 GG+ V Q FGE T+ P I F+ AKFDG+LGM +P +V V PVFD+++ Q ++ + +F Sbjct: 1 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIF 60 Query: 223 SVYYNRGSHLL-GGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEG 281 S Y +R GGE++LGG+D ++Y+G+ Y+++++ WQ+ + V V S LC+EG Sbjct: 61 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 120 Query: 282 CAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTL 341 C +VDTG+S + P ++ + +A+GA EY++ C +V TLP I+ LGG+ Y L Sbjct: 121 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 180 Query: 342 SSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 S DY L+ LC MDIPPP+GP+W+LG FI ++YT FDR NNR+GFA A Sbjct: 181 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEA 240 >1QDM-A nrPDB Length = 478 Score = 211 bits (538), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 114/239 (47%), Positives = 157/239 (65%), Gaps = 4/239 (1%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 V L NY+N QY+GEIG+GTPPQ F VIFDTGS+NLWVPS KC +AC +HS Y++ S Sbjct: 44 VALKNYMNAQYFGEIGVGTPPQKFTVIFDTGSSNLWVPSAKC-YFSIACYLHSRYKAGAS 102 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVL 192 S+Y +NG I YG+G + G+ S+DSVTVG + V Q F E T+ P I F++AKFDG+L Sbjct: 103 STYKKNGKPAAIQYGTGSIAGYFSEDSVTVGDLVVKDQEFIEATKEPGITFLVAKFDGIL 162 Query: 193 GMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQGNF 251 G+GF +VG PV+ ++ QG++ + VFS + NR GGE++ GG DP+HY G Sbjct: 163 GLGFKEISVGKAVPVWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDPKHYVGEH 222 Query: 252 HYVSISKTDSWQITMKGVSV-GSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA 309 YV +++ WQ M V V G ST C GCA + D+G+S ++ PT+ + I + +GA Sbjct: 223 TYVPVTQKGYWQFDMGDVLVGGKSTGFCAGGCAAIADSGTSLLAGPTAIITEINEKIGA 281 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 56/208 (26%), Positives = 94/208 (45%), Gaps = 12/208 (5%) Query: 204 VTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQ 263 +T + + I + GV+ +E ++ G +L +++L + P+ + T Sbjct: 272 ITEINEKIGAAGVVSQECKTIVSQYGQQIL--DLLLAETQPKKICSQVGLCTFDGTRGVS 329 Query: 264 ITMKGV----SVGSSTLLCEEGCAV----VVDTGSSFISAPTSSLKL--IMQALGAKEKR 313 ++ V V S+ L + C+ VV + T L L + Q Sbjct: 330 AGIRSVVDDEPVKSNGLRADPMCSACEMAVVWMQNQLAQNKTQDLILDYVNQLCNRLPSP 389 Query: 314 IEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGP 373 + E V+C + ++PDI F +GG+ + L +Y+L+ C AMDIPPP GP Sbjct: 390 MGESAVDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQCISGFTAMDIPPPRGP 449 Query: 374 VWVLGATFIRKFYTEFDRHNNRIGFALA 401 +W+LG F+ ++T FD RIGFA A Sbjct: 450 LWILGDVFMGPYHTVFDYGKLRIGFAKA 477 >1B5F-A nrPDB Length = 239 Score = 202 bits (514), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 114/243 (46%), Positives = 153/243 (62%), Gaps = 8/243 (3%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYES 130 ++ V LTN +T Y+GEIGIGTPPQ F VIFDTGS+ LWVPS+KC AC HS+YES Sbjct: 2 SAVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKCIN-SKACRAHSMYES 60 Query: 131 SDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFD 189 SDSS+Y ENG+ I YG+G + GF SQDSVT+G + V Q F E T+ F+ FD Sbjct: 61 SDSSTYKENGTFGAIIYGTGSITGFFSQDSVTIGDLVVKEQDFIEATDEADNVFLHRLFD 120 Query: 190 GVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQ 248 G+LG+ F +V PV+ ++L+QG++KE FS + NR GGE+V GG DP H++ Sbjct: 121 GILGLSFQTISV----PVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELVFGGLDPNHFR 176 Query: 249 GNFHYVSISKTDSWQITMKGVSVGS-STLLCEEGCAVVVDTGSSFISAPTSSLKLIMQAL 307 G+ YV ++ WQ + V +G ST C GC D+G+S +S PT+ + I A+ Sbjct: 177 GDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHAI 236 Query: 308 GAK 310 GA Sbjct: 237 GAN 239 >3QS1-A nrPDB Length = 336 Score = 189 bits (481), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 115/344 (33%), Positives = 185/344 (53%), Gaps = 14/344 (4%) Query: 62 TKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA 121 T++P L N V L + N YYGE IG Q F IFDTGSANLWVPS +C+ + Sbjct: 1 TQKPHLGNAGDSVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCNT--IG 58 Query: 122 CGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLI 181 C +LY+S+ S +Y ++G+ ++Y SG V GF S+D VT+ ++ F EVT+ Sbjct: 59 CKTKNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFPYKFIEVTDTNGF 118 Query: 182 --PFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVL 239 + L +FDG++G+G+ ++G V PV + +Q +++ VF+ Y G + + Sbjct: 119 EPAYTLGQFDGIVGLGWKDLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDK-HKGYLTI 177 Query: 240 GGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSS 299 GG + + Y+G Y ++ WQ+ + + G+ T+ E +VD+G+S I+APT Sbjct: 178 GGIEDRFYEGQLTYEKLNHDLYWQVDLD-LHFGNLTV---EKATAIVDSGTSSITAPTEF 233 Query: 300 LKLIMQALG-AKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLC 358 L + L K + Y+ C+ P LP + F YTL Y+ Q + LC Sbjct: 234 LNKFFEGLDVVKIPFLPLYITTCNN-PKLPTLEFRSATNVYTLEPEYYLQQIFDFGISLC 292 Query: 359 TLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 +++ +D+ T ++LG F+RK++T FD N+ +GFALA+ Sbjct: 293 MVSIIPVDLNKNT---FILGDPFMRKYFTVFDYDNHTVGFALAK 333 >2ANL-A nrPDB Length = 327 Score = 186 bits (473), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 113/335 (33%), Positives = 185/335 (55%), Gaps = 20/335 (5%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 + L + N +YGE +G Q F +IFDTGSANLWVPS KC+ + C LY+SS S Sbjct: 6 IELDDVANLMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSI--GCSTKHLYDSSKS 63 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FMLAKFDGV 191 SY ++G+ I YGSG V+GF S+D VT+G +++ F EVT+ + + A+FDG+ Sbjct: 64 KSYEKDGTKVEITYGSGTVRGFFSKDLVTLGYLSLPYKFIEVTDTDDLEPLYTAAEFDGI 123 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVY---YNRGSHLLGGEVVLGGSDPQHYQ 248 LG+G+ ++G + P+ + +Q + + +F+ Y +++ S G + +GG + + Y+ Sbjct: 124 LGLGWKDLSIGSIDPIVVELKNQNKIDQALFTFYLPVHDKHS----GYLTIGGIEEKFYE 179 Query: 249 GNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALG 308 G Y ++ WQ+ + V+ G +++ E V+VD+G+S I+APTS + + L Sbjct: 180 GELTYEKLNHDLFWQVDLD-VNFGKTSM---EKANVIVDSGTSTITAPTSFINKFFKDLN 235 Query: 309 A-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDI 367 K + Y+ C+ +P + F YTL Y+ + D LC L + +DI Sbjct: 236 VIKVPFLPFYITTCNN-KDMPTLEFKSANNTYTLEPEYYMEPLLDIDDTLCMLYILPVDI 294 Query: 368 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 T ++LG F+RK++T FD IGFA+A+ Sbjct: 295 DKNT---FILGDPFMRKYFTVFDYDKESIGFAVAK 326 >1MIQ-A nrPDB Length = 375 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 115/345 (33%), Positives = 182/345 (52%), Gaps = 14/345 (4%) Query: 61 FTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYL 120 + K+ L + + L + N +YGE +G Q F +IFDTGSANLWVPS KC+ Sbjct: 41 YMKQNYLGSENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSS-- 98 Query: 121 ACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPL 180 C I +LY+SS S SY ++G+ I YGSG VKGF S+D VT+G +++ F EVT+ Sbjct: 99 GCSIKNLYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVTLGHLSMPYKFIEVTDTDD 158 Query: 181 IP--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVV 238 + + +FDG+LG+G+ ++G + P+ + +Q + +F+ +Y + G + Sbjct: 159 LEPIYSSVEFDGILGLGWKDLSIGSIDPIVVELKNQNKIDNALFT-FYLPVHDVHAGYLT 217 Query: 239 LGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTS 298 +GG + + Y+GN Y ++ WQI + V G T+ E V+VD+G++ I+AP+ Sbjct: 218 IGGIEEKFYEGNITYEKLNHDLYWQIDL-DVHFGKQTM---EKANVIVDSGTTTITAPSE 273 Query: 299 SLKLIMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 L L K + YV C +P + F YTL Y+ D L Sbjct: 274 FLNKFFANLNVIKVPFLPFYVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTL 332 Query: 358 CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C + + +DI T ++LG F+RK++T FD +GFA+A+ Sbjct: 333 CMITMLPVDIDSNT---FILGDPFMRKYFTVFDYDKESVGFAIAK 374 >1QS8-A nrPDB Length = 329 Score = 182 bits (462), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 112/332 (33%), Positives = 176/332 (53%), Gaps = 14/332 (4%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 + L + N +YGE +G Q F +IFDTGSANLWVPS KC+ C I +LY+SS S Sbjct: 8 IELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSS--GCSIKNLYDSSKS 65 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FMLAKFDGV 191 SY ++G+ I YGSG VKGF S+D VT+G +++ F EV + + + +FDG+ Sbjct: 66 KSYEKDGTKVDITYGSGTVKGFFSKDLVTLGHLSMPYKFIEVIDTDDLEPIYSSVEFDGI 125 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNF 251 LG+G+ ++G + P+ + +Q + +F+ +Y + G + +GG + + Y+GN Sbjct: 126 LGLGWKDLSIGSIDPIVVELKNQNKIDNALFT-FYLPVHDVHAGYLTIGGIEEKFYEGNI 184 Query: 252 HYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA-K 310 Y ++ WQI + V G T+ E V+VD+G++ I+AP+ L L K Sbjct: 185 TYEKLNHDLYWQIDLD-VHFGKQTM---EKANVIVDSGTTTITAPSEFLNKFFANLNVIK 240 Query: 311 EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPP 370 + YV C +P + F YTL Y+ D LC + + +DI Sbjct: 241 VPFLPFYVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDIDSN 299 Query: 371 TGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 T ++LG F+RK++T FD +GFA+A+ Sbjct: 300 T---FILGDPFMRKYFTVFDYDKESVGFAIAK 328 >5BWY-A nrPDB Length = 376 Score = 174 bits (442), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 111/346 (32%), Positives = 178/346 (51%), Gaps = 18/346 (5%) Query: 62 TKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA 121 TK L + + L ++ N +YG+ +G Q F I DTGSANLWVPS KC+ Sbjct: 41 TKTNYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AG 98 Query: 122 CGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLI 181 C LY+SS S +Y ++G+ ++Y SG V GF S+D VTVG +++ F EV + Sbjct: 99 CLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGF 158 Query: 182 P--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVY---YNRGSHLLGGE 236 + + FDG+LG+G+ ++G V P+ + +Q ++ +F+ Y +++ + G Sbjct: 159 EPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHT----GF 214 Query: 237 VVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAP 296 + +GG + + Y+G Y ++ WQIT+ VG+ L E +VD+G+S I+ P Sbjct: 215 LTIGGIEERFYEGPLTYEKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITVP 270 Query: 297 TSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDK 356 T L ++Q L + + V LP F YTL Y+ + Sbjct: 271 TDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPG 330 Query: 357 LCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 LC L + +D P PT ++LG F+RK++T FD N+ +G ALA+ Sbjct: 331 LCMLNIIGLDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAK 373 >2BJU-A nrPDB Length = 453 Score = 174 bits (442), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 111/346 (32%), Positives = 178/346 (51%), Gaps = 18/346 (5%) Query: 62 TKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA 121 TK L + + L ++ N +YG+ +G Q F I DTGSANLWVPS KC+ Sbjct: 118 TKTNYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AG 175 Query: 122 CGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLI 181 C LY+SS S +Y ++G+ ++Y SG V GF S+D VTVG +++ F EV + Sbjct: 176 CLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGF 235 Query: 182 P--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVY---YNRGSHLLGGE 236 + + FDG+LG+G+ ++G V P+ + +Q ++ +F+ Y +++ + G Sbjct: 236 EPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHT----GF 291 Query: 237 VVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAP 296 + +GG + + Y+G Y ++ WQIT+ VG+ L E +VD+G+S I+ P Sbjct: 292 LTIGGIEERFYEGPLTYEKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITVP 347 Query: 297 TSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDK 356 T L ++Q L + + V LP F YTL Y+ + Sbjct: 348 TDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPG 407 Query: 357 LCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 LC L + +D P PT ++LG F+RK++T FD N+ +G ALA+ Sbjct: 408 LCMLNIIGLDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAK 450 >1XDH-A nrPDB Length = 331 Score = 173 bits (439), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 109/332 (32%), Positives = 171/332 (51%), Gaps = 14/332 (4%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 + L ++ N +YG+ +G Q F I DTGSANLWVPS KC+ C LY+SS S Sbjct: 8 IELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGCLTKHLYDSSKS 65 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FMLAKFDGV 191 +Y ++G+ ++Y SG V GF S+D VTVG +++ F EV + + + FDG+ Sbjct: 66 RTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYTASTFDGI 125 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYN-RGSHLLGGEVVLGGSDPQHYQGN 250 LG+G+ ++G V P+ + +Q ++ +F+ Y H G + +GG + + Y+G Sbjct: 126 LGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDKHT--GFLTIGGIEERFYEGP 183 Query: 251 FHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK 310 Y ++ WQIT+ VG+ L E +VD+G+S I+ PT L ++Q L Sbjct: 184 LTYEKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITVPTDFLNKMLQNLDVI 239 Query: 311 EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPP 370 + + V LP F YTL Y+ + LC L + +D P P Sbjct: 240 KVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIGLDFPVP 299 Query: 371 TGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 T ++LG F+RK++T FD N+ +G ALA+ Sbjct: 300 T---FILGDPFMRKYFTVFDYDNHSVGIALAK 328 >5JOD-A nrPDB Length = 375 Score = 171 bits (433), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 110/346 (31%), Positives = 177/346 (51%), Gaps = 16/346 (4%) Query: 61 FTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYL 120 + ++ L + + L + N +YGE IGT Q F IFDTGSANLWVPS C + Sbjct: 40 YAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDS--I 97 Query: 121 ACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPL 180 C LY++S S SY ++G+ I YGSG V+G+ S+D +++G +++ F EVT+ Sbjct: 98 GCSTKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADD 157 Query: 181 IP--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYN-RGSHLLGGEV 237 + + ++FDG+LG+G+ ++G + PV + Q + +F+ Y H+ G + Sbjct: 158 LEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHV--GYL 215 Query: 238 VLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPT 297 +GG + Y+G Y ++ WQI + + G + + VVD+G+S I+APT Sbjct: 216 TIGGIESDFYEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPT 271 Query: 298 SSLKLIMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDK 356 S L + + K + YV C LP + F YTL Y+ + Sbjct: 272 SFLNKFFRDMNVIKVPFLPLYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPA 330 Query: 357 LCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 LC L + +DI T ++LG F+RK++T FD +GFA+A+ Sbjct: 331 LCMLYILPVDIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVAK 373 >5I70-B nrPDB Length = 328 Score = 170 bits (431), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 109/333 (32%), Positives = 172/333 (51%), Gaps = 16/333 (4%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 + L + N +YGE IGT Q F IFDTGSANLWVPS C + C LY++S S Sbjct: 6 IELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDS--IGCSTKHLYDASAS 63 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FMLAKFDGV 191 SY ++G+ I YGSG V+G+ S+D +++G +++ F EVT+ + + ++FDG+ Sbjct: 64 KSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGSEFDGI 123 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYN-RGSHLLGGEVVLGGSDPQHYQGN 250 LG+G+ ++G + PV + Q + +F+ Y H+ G + +GG + Y+G Sbjct: 124 LGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHV--GYLTIGGIESDFYEGP 181 Query: 251 FHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA- 309 Y ++ WQI + + G + + VVD+G+S I+APTS L + + Sbjct: 182 LTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTSFLNKFFRDMNVI 237 Query: 310 KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPP 369 K + YV C LP + F YTL Y+ + LC L + +DI Sbjct: 238 KVPFLPLYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDD 296 Query: 370 PTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 T ++LG F+RK++T FD +GFA+A+ Sbjct: 297 NT---FILGDPFMRKYFTVFDYEKESVGFAVAK 326 >3QVI-A nrPDB Length = 451 Score = 144 bits (364), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 98/347 (28%), Positives = 174/347 (50%), Gaps = 20/347 (5%) Query: 62 TKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA 121 TK+ L + V L + N +GE +G Q F +F T S+N+WVPS KC+ + Sbjct: 117 TKKSYLGSEFDNVELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTS--ES 174 Query: 122 CGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELP-L 180 C + Y+SS S +Y ++ + + +G + G S+D VT+G ++V F E+TE+ Sbjct: 175 CESKNHYDSSKSKTYEKDDTPVKLTSKAGTISGIFSKDLVTIGKLSVPYKFIEMTEIVGF 234 Query: 181 IPFM-LAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYY---NRGSHLLGGE 236 PF + DGV G+G+ ++G + P + +Q +++ V+S+Y N+ G Sbjct: 235 EPFYSESDVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLPPENKNK----GY 290 Query: 237 VVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAP 296 + +GG + + + G +Y ++ WQ+ + V G+ + + V++D+ +S I+ P Sbjct: 291 LTIGGIEERFFDGPLNYEKLNHDLMWQVDL-DVHFGN---VSSKKANVILDSATSVITVP 346 Query: 297 TSSLKLIMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRD 355 T +++ K + YV C LP + + + YTL Y+ N Sbjct: 347 TEFFNQFVESASVFKVPFLSLYVTTCGNTK-LPTLEYRSPNKVYTLEPKQYLEPLENIFS 405 Query: 356 KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 LC L + +D+ T +VLG F+RK++T +D N+ +GFALA+ Sbjct: 406 ALCMLNIVPIDLEKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAK 449 >3FNT-A nrPDB Length = 332 Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 95/335 (28%), Positives = 169/335 (50%), Gaps = 20/335 (5%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 V L + N +GE +G Q F +F T S+N+WVPS KC+ +C + Y+SS S Sbjct: 10 VELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTS--ESCESKNHYDSSKS 67 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELP-LIPFM-LAKFDGV 191 +Y ++ + + +G + G S+D VT+G ++V F E+TE+ PF + DGV Sbjct: 68 KTYEKDDTPVKLTSKAGTISGIFSKDLVTIGKLSVPYKFIEMTEIVGFEPFYSESDVDGV 127 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYY---NRGSHLLGGEVVLGGSDPQHYQ 248 G+G+ ++G + P + +Q +++ V+S+Y N+ G + +GG + + + Sbjct: 128 FGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLPPENKNK----GYLTIGGIEERFFD 183 Query: 249 GNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALG 308 G +Y ++ WQ+ + V G+ + + V++D+ +S I+ PT +++ Sbjct: 184 GPLNYEKLNHDLMWQVDL-DVHFGN---VSSKKANVILDSATSVITVPTEFFNQFVESAS 239 Query: 309 A-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDI 367 K + YV C LP + + + YTL Y+ N LC L + +D+ Sbjct: 240 VFKVPFLSLYVTTCGNT-KLPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLNIVPIDL 298 Query: 368 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 T +VLG F+RK++T +D N+ +GFALA+ Sbjct: 299 EKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAK 330 >4OD9-A nrPDB Length = 103 Score = 130 bits (327), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 60/99 (60%), Positives = 75/99 (75%) Query: 65 PSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGI 124 P++T P VL NY++ QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC I Sbjct: 1 PAVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWI 60 Query: 125 HSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTV 163 H Y S SS+Y++NG+ F IHYGSG + G+LSQD+V+V Sbjct: 61 HHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 99 >3LIZ-A nrPDB Length = 334 Score = 124 bits (311), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 94/329 (28%), Positives = 161/329 (48%), Gaps = 24/329 (7%) Query: 79 YLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYME 138 ++NTQY G IG Q F +FD+ S N+ V S +C C YE Y+ Sbjct: 16 FINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKL-KPKYIS 72 Query: 139 NGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPA 198 +G+ + +G G +DS+T+ +T +Q + + + D V+G+ P Sbjct: 73 DGNVQVKFFDTGSAVGRGIEDSLTISQLTTSQQDIVLADELSQEVCILSADVVVGIAAPG 132 Query: 199 --QAVGGVTPVFDHILSQGVLKEEVFSVYYNR---GSHLLGGEVVLGGSDPQHYQGNFHY 253 A+ G T V ++ + + ++ VFS+++ R G H GE++ GGSD ++ G F Y Sbjct: 133 CPNALKGKT-VLENFVEENLIAP-VFSIHHARFQDGEHF--GEIIFGGSDWKYVDGEFTY 188 Query: 254 VSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA-KEK 312 V + DSW+ + GV +G +T + G ++DT + I P + + I +A+G EK Sbjct: 189 VPLVGDDSWKFRLDGVKIGDTT-VAPAGTQAIIDTSKAIIVGPKAYVNPINEAIGCVVEK 247 Query: 313 RIEEYV--VNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPP 370 + ++CS++P+LPD++F + GR + +SS Y+ Q N LC P Sbjct: 248 TTTRRICKLDCSKIPSLPDVTFVINGRNFNISSQYYIQQNGN----LCYSGFQ----PCG 299 Query: 371 TGPVWVLGATFIRKFYTEFDRHNNRIGFA 399 + +G F+ +Y+EF+ N +GF Sbjct: 300 HSDHFFIGDFFVDHYYSEFNWENKTMGFG 328 >1UH8-A nrPDB Length = 325 Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 94/324 (29%), Positives = 165/324 (50%), Gaps = 22/324 (6%) Query: 74 VVLTNYLNT-QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGI-HSLYESS 131 V +T+Y N +YYG++ IGTP + F + FDTGS++LW+ ST C+ CG + Y+ + Sbjct: 6 VPMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLCTN----CGSRQTKYDPN 61 Query: 132 DSSSYMENGSDFTIHYGSG-RVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDG 190 SS+Y +G ++I YG G G L++D+V +GG+ + E+ + F DG Sbjct: 62 QSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTIELAKREAASFASGPNDG 121 Query: 191 VLGMGFPA-QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQG 249 +LG+GF V GV D+++SQG++ +F VY + + GGE + GG D ++G Sbjct: 122 LLGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYLGKAKNGGGGEYIFGGYDSTKFKG 181 Query: 250 NFHYVSISKTDS-WQITMKGVSVGSSTLLCE-EGCAVVVDTGSSFISAPTSSLKLIMQAL 307 + V I + W IT+ +VG+ST+ +G ++DTG++ + P + + +A Sbjct: 182 SLTTVPIDNSRGWWGITVDRATVGTSTVASSFDG---ILDTGTTLLILPNNIAASVARAY 238 Query: 308 GAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDI 367 GA + Y ++C P + F + G ++ +S V + + + D Sbjct: 239 GASDNGDGTYTISCDTSRFKP-LVFSINGASFQVSPDSLVFE-EFQGQCIAGFGYGNWDF 296 Query: 368 PPPTGPVWVLGATFIRKFYTEFDR 391 ++G TF++ Y F++ Sbjct: 297 A-------IIGDTFLKNNYVVFNQ 313 >2ASI-A nrPDB Length = 361 Score = 107 bits (267), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 95/344 (27%), Positives = 155/344 (45%), Gaps = 37/344 (10%) Query: 83 QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSD 142 +Y + IGTP Q F ++FDTGS++ WVP C++ C ++ S SS++ + Sbjct: 19 EYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKS-EGCVGSRFFDPSASSTFKATNYN 77 Query: 143 FTIHYGSGRVKGFLSQDSVTVGGITVTQTF--------GEVTELPLIPFMLAKFDGVLGM 194 I YG+G G +DS+ +G ITVT+ G E P DG+ G Sbjct: 78 LNITYGTGGANGLYFEDSIAIGDITVTKQILAYVDNVRGPTAEQS--PNADIFLDGLFGA 135 Query: 195 GFP------AQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQ 248 +P A+ V ++ QG++ +FSVY N S GEVV GG + Sbjct: 136 AYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMNTNSGT--GEVVFGGVNNTLLG 193 Query: 249 GNFHYVSISKTDS----WQITMKGVSV-GSSTLLCEEGCAVVVDTGSSFISAPTSSL-KL 302 G+ Y + W + G++V GS+ + A +DTG++F P+S+ K+ Sbjct: 194 GDIAYTDVMSRYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTIDTGTNFFIMPSSAASKI 253 Query: 303 IMQALGAKEKRIEEYVVNCSQV----PTLPDISFDLGGRAYTLSST---DYVLQYPNRRD 355 + AL + + +VV C+ T+ + G + T+ + +L ++ + Sbjct: 254 VKAALPDATETQQGWVVPCASYQNSKSTISIVMQKSGSSSDTIEISVPVSKMLLPVDQSN 313 Query: 356 KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399 + C I P G +++G F+R F +D NNRIGFA Sbjct: 314 ETCMFI-----ILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGFA 352 >1MPP-A nrPDB Length = 361 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 97/351 (27%), Positives = 152/351 (43%), Gaps = 51/351 (14%) Query: 83 QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSD 142 +Y + IGTP Q F ++FDTGS++ WVP C C ++ S SS++ E + Sbjct: 19 EYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNS-EGCVGKRFFDPSSSSTFKETDYN 77 Query: 143 FTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTEL-----PLIPFMLAKFDGVLGMGF 196 I YG+G G +DS+TVGG TV QT V + P DG+ G + Sbjct: 78 LNITYGTGGANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSPDSELFLDGIFGAAY 137 Query: 197 P------AQAVGGVTPVFDHILSQGVLKEEVFSVYYN------------RGSHLLGGEVV 238 P A+ V ++ QG++ VFSVY N + LLGG++ Sbjct: 138 PDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVFGGVNNTLLGGDIQ 197 Query: 239 LGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGC-AVVVDTGSSFISAPT 297 +D +G + + W + GV + S + +G A +DTG++F AP+ Sbjct: 198 Y--TDVLKSRGGYFF--------WDAPVTGVKIDGSDAVSFDGAQAFTIDTGTNFFIAPS 247 Query: 298 S-SLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYP----- 351 S + K++ AL + + Y V CS+ +F L + SS + P Sbjct: 248 SFAEKVVKAALPDATESQQGYTVPCSKYQD-SKTTFSLVLQKSGSSSDTIDVSVPISKML 306 Query: 352 ---NRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399 ++ + C + P G +++G F+R F +D NRIGFA Sbjct: 307 LPVDKSGETCMFI-----VLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFA 352 >3ZKX-A nrPDB Length = 386 Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 100/348 (28%), Positives = 159/348 (45%), Gaps = 42/348 (12%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDF 143 YY E+ IGTPPQ +++ DTGS+N V T S I + +++ SS+Y G D Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 71 Query: 144 TIHYGSGRVKGFLSQDSVTV-GGITVTQTFGEVTELPLIPFML--AKFDGVLGMGFP--A 198 T+ Y G GF+ +D VT+ G + T F L K++G+LG+ + A Sbjct: 72 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 131 Query: 199 QAVGGVTPVFDHILSQGVLKEEVFSVYYN------RGSHLLGGEVVLGGSDPQHYQGNFH 252 + + FD +++Q + VFS+ GS GG +VLGG +P Y+G+ Sbjct: 132 KPSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIW 190 Query: 253 YVSISKTDSWQITMKGVSVG--SSTLLCEEGCA--VVVDTGSSFISAPTSSLKLIMQALG 308 Y I + +QI + + +G S L C E A +VD+G++ + P +++A+ Sbjct: 191 YTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAV- 249 Query: 309 AKEKRIEEYV--------VNC---SQVP--TLPDISFDL----GGRAYTLSSTDYVLQYP 351 A+ I + + C S+ P P IS L R++ ++ + P Sbjct: 250 ARASLIPAFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQP 309 Query: 352 NRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399 L + I P T + V+GAT + FY FDR R+GFA Sbjct: 310 MMGAGL-NYECYRFGISPSTNAL-VIGATVMEGFYVIFDRAQKRVGFA 355 >2QZW-A nrPDB Length = 341 Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 96/348 (27%), Positives = 163/348 (46%), Gaps = 39/348 (11%) Query: 73 PVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVP--STKCSRLYLA-----CGIH 125 PV L N + Y +I IG+ Q F VI DTGS++LWVP S C + C Sbjct: 4 PVTLNNE-HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 62 Query: 126 SLYESSDSSSYMENGSDFTIHYGSG-RVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPF 183 +Y S++ G+ F I YG G +G L +D+V GG ++T Q F ++T+ IP Sbjct: 63 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTS-IP- 120 Query: 184 MLAKFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGS 242 G+LG+G+ +A G V + +QGV+ + +S+Y N + G+++ GG Sbjct: 121 -----QGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATGQIIFGGV 174 Query: 243 DPQHYQGNFHYVSISKTDSWQITMKGV-SVGSSTLLCEEGCAVVVDTGSSFISAPTSSLK 301 D Y G+ V ++ +IT+ + +VG + V++D+G++ + Sbjct: 175 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKN---INGNIDVLLDSGTTITYLQQDVAQ 231 Query: 302 LIMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGRAYTLSSTDYV--LQYPNRRD 355 I+ A A+ K + YV +C T+ D +FD + ++ ++++ L Y N + Sbjct: 232 DIIDAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFDNNAK-ISVPASEFTAPLSYANGQP 289 Query: 356 -KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C L L D +LG F+R Y +D +++I A + Sbjct: 290 YPKCQLLLGISD-------ANILGDNFLRSAYLVYDLDDDKISLAQVK 330 >3FV3-A nrPDB Length = 339 Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 86/338 (25%), Positives = 155/338 (45%), Gaps = 41/338 (12%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWV--PSTKCSRLYLACGIHSLYESSDSSSYMENGS 141 Y ++ +G+ Q VI DTGS++ WV + +C + + C + S SSSY G+ Sbjct: 14 YASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKG-VDCKSSGTFTPSSSSSYKNLGA 72 Query: 142 DFTIHYGSGRV-KGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPA- 198 FTI YG G +G +D+VT+ G+++T Q +VT+ + G+LG+G+ + Sbjct: 73 AFTIRYGDGSTSQGTWGKDTVTINGVSITGQQIADVTQTSVDQ-------GILGIGYTSN 125 Query: 199 QAV-----GGVTPVFDHI----LSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQG 249 +AV TP +D++ QG ++ +S+Y N S G ++ GG D Y G Sbjct: 126 EAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYLNSPSAET-GTIIFGGVDNAKYSG 184 Query: 250 NFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA 309 ++ + + I++ V++ S+ +G ++D+G++ P+ + GA Sbjct: 185 KLVAEQVTSSQALTISLASVNLKGSSFSFGDGA--LLDSGTTLTYFPSDFAAQLADKAGA 242 Query: 310 KEKRIEE----YVVNCSQVPTLPDISFDLG-GRAYTLSSTDYVLQYPNRRDKLCTLALHA 364 + ++ Y ++C+ T F+ G G T+ +T+YV Q D C + Sbjct: 243 RLVQVARDQYLYFIDCN-TDTSGTTVFNFGNGAKITVPNTEYVYQ---NGDGTCLWGIQP 298 Query: 365 MDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 D +LG F+R Y ++ N I A + Sbjct: 299 SDDT-------ILGDNFLRHAYLLYNLDANTISIAQVK 329 >3PVK-A nrPDB Length = 342 Score = 88.2 bits (217), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 90/352 (25%), Positives = 155/352 (44%), Gaps = 46/352 (13%) Query: 73 PVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVP--STKCSRLYLA-----CGIH 125 PV L N T Y +I +G+ Q VI DTGS++LWVP + C Y C Sbjct: 4 PVTLHNEQVT-YAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQK 62 Query: 126 SLYESSDSSSYMENGSDFTIHYGSG-RVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPF 183 Y+ S SS+ + + F I YG G +G L +D+V GG+++ Q +V + Sbjct: 63 GTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSIDQ- 121 Query: 184 MLAKFDGVLGMGFPAQAVGGVTPVFDHI----LSQGVLKEEVFSVYYNRGSHLLGGEVVL 239 G+LG+G+ GG +D++ QGV+ + +S+Y N G+++ Sbjct: 122 ------GILGVGYKTNEAGG---SYDNVPVTLKKQGVIAKNAYSLYLNS-PDAATGQIIF 171 Query: 240 GGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSS 299 GG D Y G+ + ++ +I++ V V T+ + V++D+G++ Sbjct: 172 GGVDNAKYSGSLIALPVTSDRELRISLGSVEVSGKTINTDN-VDVLLDSGTTITYLQQDL 230 Query: 300 LKLIMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGRA-YTLSSTDYV--LQYPN 352 I++A K + Y V+C+ D+ F+ A ++ ++++ LQ + Sbjct: 231 ADQIIKAFNGKLTQDSNGNSFYEVDCN---LSGDVVFNFSKNAKISVPASEFAASLQGDD 287 Query: 353 RR--DKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 + DK C L D +LG F+R Y +D +N I A + Sbjct: 288 GQPYDK-CQLLFDVND-------ANILGDNFLRSAYIVYDLDDNEISLAQVK 331 >1WKR-A nrPDB Length = 340 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 84/339 (24%), Positives = 151/339 (44%), Gaps = 45/339 (13%) Query: 83 QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSD 142 Y +G+G+P T+ ++ DTGS+N W+ + K S ++S SS+ + Sbjct: 13 DYVVNVGVGSPATTYSLLVDTGSSNTWLGADK-----------SYVKTSTSSATSDK--- 58 Query: 143 FTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 201 ++ YGSG G D+VT+G +T+ Q+ G + DG+LG+G V Sbjct: 59 VSVTYGSGSFSGTEYTDTVTLGSLTIPKQSIGVASR----DSGFDGVDGILGVGPVDLTV 114 Query: 202 GGVTP--------VFDHILSQGVLKEEVFSVYY--NRGSHLLGGEVVLGGSDPQHYQGNF 251 G ++P V D++ SQG + + +V + GE+ G +D Y G+ Sbjct: 115 GTLSPHTSTSIPTVTDNLFSQGTIPTNLLAVSFEPTTSESSTNGELTFGATDSSKYTGSI 174 Query: 252 HYVSISKTDS----WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQAL 307 Y I+ T W I + + GSST + A +VDTG++ + + +A Sbjct: 175 TYTPITSTSPASAYWGIN-QSIRYGSSTSILSS-TAGIVDTGTTLTLIASDAFAKYKKAT 232 Query: 308 GA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRD-----KLCTLA 361 GA + + +Q L + F +GG+ + L++ + +P + ++ Sbjct: 233 GAVADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQI--WPRNLNTAIGGSASSVY 290 Query: 362 LHAMDIPPPTGP--VWVLGATFIRKFYTEFDRHNNRIGF 398 L D+ +G ++ G TF+ +FY+ +D N R+G Sbjct: 291 LIVGDLGSDSGEGLDFINGLTFLERFYSVYDTTNKRLGL 329 >4Y9W-A nrPDB Length = 334 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 84/339 (24%), Positives = 144/339 (42%), Gaps = 37/339 (10%) Query: 79 YLNTQYYG-EIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYM 137 Y YG + +G+ Q +V+ DTGS++ WV + S C + ++ S+S+ Sbjct: 8 YFEGPSYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYGTFDPHSSTSFK 67 Query: 138 ENGSDFTIHYGSGRVK-GFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMG 195 GS F+I YG G QD++ +GG ++T Q F +VT + G+LG+G Sbjct: 68 SLGSSFSIGYGDKSSSIGTWGQDTIYLGGTSITNQRFADVTSTSV-------NQGILGVG 120 Query: 196 FPAQAVGGVTPVFDHI----LSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNF 251 P +D++ QG +K +S+Y N G ++ GG D Y G Sbjct: 121 --RVETESANPPYDNVPITLKKQGKIKTNAYSLYLNSPGAAT-GTIIFGGVDNAKYSGKL 177 Query: 252 HYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKE 311 + + +K ++ G VVVD+G++ P S + + +GA Sbjct: 178 IEEPLVSDRYLAVNLKSLNYNGDN--SNAGFGVVVDSGTTISYLPDSIVDDLANKVGAYL 235 Query: 312 KRI----EEYVVNCSQVPT-LPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMD 366 + + E Y ++C+ P +FD G + T+ +++VLQ C L + D Sbjct: 236 EPVGLGNELYFIDCNANPQGSASFTFDNGAK-ITVPLSEFVLQ---STANACVWGLQSSD 291 Query: 367 ---IPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 +PP +LG F+R Y F+ + A + Sbjct: 292 RQNVPP------ILGDNFLRHAYVVFNLDKETVSLAQVK 324 >2H6T-A nrPDB Length = 340 Score = 85.1 bits (209), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 85/348 (24%), Positives = 153/348 (43%), Gaps = 36/348 (10%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA------CGI 124 T PV L N Y +I +G+ Q V+ DTGS++LWVP ++ S C Sbjct: 2 TVPVKLINE-QVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKN 60 Query: 125 HSLYESSDSSSYMENGSDFTIHYGSGRV-KGFLSQDSVTVGGITVT-QTFGEVTELPLIP 182 Y S SSS S F+I YG G +G +D++ GGI++T Q F +VT + Sbjct: 61 EGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVDQ 120 Query: 183 FMLAKFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGG 241 G+LG+G+ +A G V + +QG++ + +S+Y N G+++ GG Sbjct: 121 -------GILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNS-RQATSGQIIFGG 172 Query: 242 SDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLK 301 D Y G + ++ + +I + V V ++ + V++D+G++ Sbjct: 173 VDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSINAD--VDVLLDSGTTITYLQQGVAD 230 Query: 302 LIMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 ++ A +E Y+V+C+ ++ D +FD + ++ ++++ ++ Sbjct: 231 QVISAFNGQETYDANGNLFYLVDCNLSGSV-DFAFDKNAKI-SVPASEFTAPLYTEDGQV 288 Query: 358 ---CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C L D +LG F+R Y +D +N I A + Sbjct: 289 YDQCQLLFGTSDYN-------ILGDNFLRSAYIVYDLDDNEISLAQVK 329 >1J71-A nrPDB Length = 334 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 78/333 (23%), Positives = 148/333 (44%), Gaps = 36/333 (10%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPST--KCSRLYLA-----CGIHSLYESSDSSSY 136 Y +I +G+ Q V+ DTGS++LWV T +C Y C ++ S SSS Sbjct: 14 YAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFCKQEGTFDPSSSSSA 73 Query: 137 MENGSDFTIHYGS-GRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGM 194 DF+I YG +G +D+V GGI++ Q F +VT + G++G+ Sbjct: 74 QNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVTTTSVDQ-------GIMGI 126 Query: 195 GFPAQAVGGVTPVFDHI----LSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGN 250 GF A G ++D++ QG++ + +S+Y N G+++ GG D Y G Sbjct: 127 GFTADEAG--YNLYDNVPVTLKKQGIINKNAYSLYLNS-EDASTGKIIFGGVDNAKYTGT 183 Query: 251 FHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK 310 + ++ + ++ + ++ +++ VV+D+G++ S+ + +GA Sbjct: 184 LTALPVTSSVELRVHLGSINFDGTSV--STNADVVLDSGTTITYFSQSTADKFARIVGAT 241 Query: 311 -EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPP 369 + R E Y + + +FD G + T+ ++ +L+ + +C + D Sbjct: 242 WDSRNEIYRLPSCDLSGDAVFNFDQGVK-ITVPLSELILK--DSDSSICYFGISRNDAN- 297 Query: 370 PTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 +LG F+R+ Y +D + I A + Sbjct: 298 ------ILGDNFLRRAYIVYDLDDKTISLAQVK 324 >2QZX-A nrPDB Length = 342 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 81/339 (23%), Positives = 150/339 (44%), Gaps = 47/339 (13%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTK--CSRLYLA-----CGIHSLYESSDSSSY 136 Y +I +G+ Q VI DTGS++LW+P + C + C Y + S + Sbjct: 14 YTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIPKWRGDKGDFCKSAGSYSPASSRTS 73 Query: 137 MENGSDFTIHYGSGR-VKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGM 194 + F I YG G KG L +D+V +GG++V Q F V + + G+LG+ Sbjct: 74 QNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQLFANV-------WSTSARKGILGI 126 Query: 195 GFPAQAVGGVTPVFDH------ILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQ 248 GF + G FD+ + +QG++ + +S+Y N + G+++ GG D Y Sbjct: 127 GFQS----GEATEFDYDNLPISLRNQGIIGKAAYSLYLN-SAEASTGQIIFGGIDKAKYS 181 Query: 249 GNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALG 308 G+ + I+ + ++ V+V + + V++D+G++ S ++ I+ A+G Sbjct: 182 GSLVDLPITSEKKLTVGLRSVNVRGRNV--DANTNVLLDSGTTISYFTRSIVRNILYAIG 239 Query: 309 AKEK----RIEEYVVNCSQVPTLPDISFDLGGR-AYTLSSTDYVLQYPNRRDK---LCTL 360 A+ K + YV +C T I F G ++ ++++ Q K C + Sbjct: 240 AQMKFDSAGNKVYVADCKTSGT---IDFQFGNNLKISVPVSEFLFQTYYTSGKPFPKCEV 296 Query: 361 ALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399 + + +LG F+R Y ++ + +I A Sbjct: 297 RIRESEDN-------ILGDNFLRSAYVVYNLDDKKISMA 328 >3TPL-A nrPDB Length = 433 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 90/353 (25%), Positives = 151/353 (42%), Gaps = 44/353 (12%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDF 143 YY E+ +G+PPQT ++ DTGS+N V + L H Y+ SS+Y + Sbjct: 54 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 107 Query: 144 TIHYGSGRVKGFLSQDSVTV---GGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFP--A 198 + Y G G L D V++ +TV +TE + ++G+LG+ + A Sbjct: 108 YVPYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 167 Query: 199 QAVGGVTPVFDHILSQGVLKEEVFSVY-------YNRGSHL--LGGEVVLGGSDPQHYQG 249 + + P FD ++ Q + +FS+ N+ L +GG +++GG D Y G Sbjct: 168 RPDDSLEPFFDSLVKQTHVP-NLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTG 226 Query: 250 NFHYVSISKTDSWQITMKGVSVGSSTLL--CEEGC--AVVVDTGSSFISAPTSSLKLIMQ 305 + Y I + +++ + V + L C+E +VD+G++ + P + ++ Sbjct: 227 SLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVK 286 Query: 306 ALGAK---EKRIEEYVVN----CSQVPT-----LPDISFDLGGRAYTLSSTDYVL--QYP 351 ++ A EK + + + C Q T P IS L G S +L QY Sbjct: 287 SIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYL 346 Query: 352 NRRDKLCTLALHAMDIP---PPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 + + T TG V+GA + FY FDR RIGFA++ Sbjct: 347 RPVEDVATSQDDCYKFAISQSSTGT--VMGAVIMEGFYVVFDRARKRIGFAVS 397 >4B1C-A nrPDB Length = 375 Score = 67.4 bits (163), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 88/344 (25%), Positives = 149/344 (43%), Gaps = 40/344 (11%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDF 143 YY E+ +G+PPQT ++ DTGS+N V + L H Y+ SS+Y + Sbjct: 20 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 73 Query: 144 TIHYGSGRVKGFLSQDSVTV---GGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFP--A 198 + Y G+ +G L D V++ +TV +TE + ++G+LG+ + A Sbjct: 74 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 133 Query: 199 QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISK 258 + + P FD ++ Q + +FS+ GG +++GG D Y G+ Y I + Sbjct: 134 RPDDSLEPFFDSLVKQTHVP-NLFSL-----QLCGGGSMIIGGIDHSLYTGSLWYTPIRR 187 Query: 259 TDSWQITMKGVSVGSSTLL--CEEGC--AVVVDTGSSFISAPTSSLKLIMQALGAK---E 311 +++ + V + L C+E +VD+G++ + P + ++++ A E Sbjct: 188 EWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTE 247 Query: 312 KRIEEYVVN----CSQVPT-----LPDISFDLGGRAYTLSSTDYVL--QYPNRRDKLCTL 360 K + + + C Q T P IS L G S +L QY + + T Sbjct: 248 KFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATS 307 Query: 361 ALHAMDIP---PPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 TG V+GA + FY FDR RIGFA++ Sbjct: 308 QDDCYKFAISQSSTGT--VMGAVIMEGFYVVFDRARKRIGFAVS 349 >1B5F-B nrPDB Length = 87 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Query: 315 EEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPV 374 EE V+C+ + ++P++SF +GG+ + L+ Y+L+ C AMD GP+ Sbjct: 1 EELQVDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMD-ATLLGPL 59 Query: 375 WVLGATFIRKFYTEFDRHNNRIGFALA 401 W+LG F+R ++T FD N +GFA A Sbjct: 60 WILGDVFMRPYHTVFDYGNLLVGFAEA 86 >1PPK-E nrPDB Length = 323 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 86/315 (27%), Positives = 136/315 (43%), Gaps = 32/315 (10%) Query: 96 TFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSG-RVKG 154 T + FDTGSA+LWV ST+ + HS+Y S + + +G ++I YG G G Sbjct: 27 TLNLNFDTGSADLWVFSTELPASQQSG--HSVYNPSATGKEL-SGYTWSISYGDGSSASG 83 Query: 155 FLSQDSVTVGGITVTQTFGEVTELPLIPFML-AKFDGVLGMGFPAQAVGGVTP-----VF 208 + DSVTVGG+T + + F DG+LG+ F ++ V P F Sbjct: 84 NVFTDSVTVGGVTAHGQAVQAAQQISAQFQQDTNNDGLLGLAF--SSINTVQPQSQTTFF 141 Query: 209 DHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS-WQITMK 267 D + S L + +F+V H G G D Y G+ Y + + W + Sbjct: 142 DTVKSS--LAQPLFAVALK---HQQPGVYDFGFIDSSKYTGSLTYTGVDNSQGFWSFNVD 196 Query: 268 GVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSL-KLIMQALGA-KEKRIEEYVVNCSQVP 325 + GS + +G + + DTG++ + S + + Q GA ++ YV +CS Sbjct: 197 SYTAGSQS---GDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSNAGGYVFDCS--T 251 Query: 326 TLPDISFDLGGRAYTLSSTDYVLQY-PNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRK 384 LPD S + G YT + ++ Y P+ C L + G + G F++ Sbjct: 252 NLPDFSVSISG--YTATVPGSLINYGPSGDGSTC---LGGIQSNSGIG-FSIFGDIFLKS 305 Query: 385 FYTEFDRHNNRIGFA 399 Y FD ++GFA Sbjct: 306 QYVVFDSDGPQLGFA 320 >5HCT-A nrPDB Length = 419 Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 80/284 (28%), Positives = 131/284 (46%), Gaps = 26/284 (9%) Query: 63 KRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLAC 122 +R + + T+P+ + L+ Y + IGTP QT + FDTGS++LWV S++ + + Sbjct: 88 ERSTGSATTTPI---DSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDG 144 Query: 123 GIHSLYESSDSSS--YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPL 180 ++Y S S++ + + + G + D+V+VGG+TVT E + Sbjct: 145 --QTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVS 202 Query: 181 IPFML-AKFDGVLGMGFPAQAVGGVTPV-----FDHILSQGVLKEEVFSVYYNRGSHLLG 234 F + DG+LG+ F + V+P FD+ ++ L VF+ + G H Sbjct: 203 SSFTEDSTIDGLLGLAF--STLNTVSPTQQKTFFDN--AKASLDSPVFTA--DLGYHAP- 255 Query: 235 GEVVLGGSDPQHYQGNFHYVSIS-KTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFI 293 G G D Y G+ Y ++S K W+ T G +VGS T + DTG++ + Sbjct: 256 GTYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTS-IDGIADTGTTLL 314 Query: 294 SAPTSSLKLI-MQALGAK-EKRIEEYVVNCSQVPTLPDISFDLG 335 P + + Q GAK + YV CS TLP +F +G Sbjct: 315 YLPATVVSAYWAQVSGAKSSSSVGGYVFPCSA--TLPSFTFGVG 356 >3PI0-A nrPDB Length = 330 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 79/276 (28%), Positives = 127/276 (46%), Gaps = 26/276 (9%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYES 130 T+P+ + L+ Y + IGTP QT + FDTGS++LWV S++ + + ++Y Sbjct: 7 TTPI---DSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDG--QTIYTP 61 Query: 131 SDSSS--YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFML-AK 187 S S++ + + + G + D+V+VGG+TVT E + F + Sbjct: 62 SKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSSFTEDST 121 Query: 188 FDGVLGMGFPAQAVGGVTPV-----FDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGS 242 DG+LG+ F + V+P FD+ ++ L VF+ + G H G G Sbjct: 122 IDGLLGLAF--STLNTVSPTQQKTFFDN--AKASLDSPVFTA--DLGYHAP-GTYNFGFI 174 Query: 243 DPQHYQGNFHYVSIS-KTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLK 301 D Y G+ Y ++S K W+ T G +VGS T + DTG++ + P + + Sbjct: 175 DTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTS-IDGIADTGTTLLYLPATVVS 233 Query: 302 LI-MQALGAK-EKRIEEYVVNCSQVPTLPDISFDLG 335 Q GAK + YV CS TLP +F +G Sbjct: 234 AYWAQVSGAKSSSSVGGYVFPCSA--TLPSFTFGVG 267 >1IZE-A nrPDB Length = 323 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 84/330 (25%), Positives = 134/330 (40%), Gaps = 34/330 (10%) Query: 81 NTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENG 140 + +Y ++ +G T + FDTGSA+LWV S++ + H Y S+ ++ G Sbjct: 14 DEEYITQVTVG--DDTLGLDFDTGSADLWVFSSQTPSSERSG--HDYYTPGSSAQKID-G 68 Query: 141 SDFTIHYGSG-RVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFML-AKFDGVLGMGFPA 198 + ++I YG G G + +D VTVGG++ E E F DG+LG+ F + Sbjct: 69 ATWSISYGDGSSASGDVYKDKVTVGGVSYDSQAVESAEKVSSEFTQDTANDGLLGLAFSS 128 Query: 199 QAVGGVTP---VFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVS 255 TP FD++ S L E +F+V H G G +D Y G+ Y Sbjct: 129 INTVQPTPQKTFFDNVKSS--LSEPIFAVALK---HNAPGVYDFGYTDSSKYTGSITYTD 183 Query: 256 ISKTDS-WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRI 314 + + W T G S+GS + + DTG++ + S + + + Sbjct: 184 VDNSQGFWGFTADGYSIGSDSSSDS--ITGIADTGTTLLLLDDSIVDAYYEQVNGASYDS 241 Query: 315 EE--YVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAM--DIPPP 370 + YV S +LPD S +G DY P + I Sbjct: 242 SQGGYVFPSS--ASLPDFSVTIG---------DYTATVPGEYISFADVGNGQTFGGIQSN 290 Query: 371 TGPVW-VLGATFIRKFYTEFDRHNNRIGFA 399 +G + + G F++ Y FD R+GFA Sbjct: 291 SGIGFSIFGDVFLKSQYVVFDASGPRLGFA 320 >1IBQ-A nrPDB Length = 325 Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 80/323 (24%), Positives = 131/323 (40%), Gaps = 45/323 (13%) Query: 96 TFKVIFDTGSANLWV-----PSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSG 150 T + FDTGSA+LWV PS++ + H LY S S++ + +G + I YG G Sbjct: 26 TLHLDFDTGSADLWVFSDELPSSEQTG-------HDLYTPSSSATKL-SGYSWDISYGDG 77 Query: 151 R-VKGFLSQDSVTVGGITVTQTFGEVTELPLIPFML-AKFDGVLGMGFPAQAVGGVTP-- 206 G + +D+VTVGG+T + E F+ DG+LG+ F ++ V P Sbjct: 78 SSASGDVYRDTVTVGGVTTNKQAVEAASKISSEFVQDTANDGLLGLAF--SSINTVQPKA 135 Query: 207 ---VFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQ 263 FD + SQ L +F+V + H G G D Y G+ Y + + Sbjct: 136 QTTFFDTVKSQ--LDSPLFAV---QLKHDAPGVYDFGYIDDSKYTGSITYTDADSSQGYW 190 Query: 264 ITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEE--YVVNC 321 G + + DTG++ I + + + ++ E YV +C Sbjct: 191 GFSTDGYSIGDGSSSSSGFSAIADTGTTLILLDDEIVSAYYEQVSGAQESYEAGGYVFSC 250 Query: 322 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAM----DIPPPTG-PVWV 376 S LPD + +G DY P + ++ + I +G + + Sbjct: 251 S--TDLPDFTVVIG---------DYKAVVPGKYINYAPVSTGSSTCYGGIQSNSGLGLSI 299 Query: 377 LGATFIRKFYTEFDRHNNRIGFA 399 LG F++ Y F+ ++GFA Sbjct: 300 LGDVFLKSQYVVFNSEGPKLGFA 322 >4ZL4-A nrPDB Length = 444 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 52/188 (27%), Positives = 80/188 (42%), Gaps = 37/188 (19%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIH-----SLYESSDSSS-YM 137 Y+ +I IGTP Q +I DTGS++L P C CG+H +L S SS Y Sbjct: 30 YFLDIDIGTPEQRISLILDTGSSSLSFPCAGCKN----CGVHMENPFNLNNSKTSSILYC 85 Query: 138 EN------------GSDFTIHYGSG-RVKGFLSQDSVTVGG-----ITVTQTFG-EVTEL 178 EN ++ Y G ++ GF D V+V +T + G + E Sbjct: 86 ENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSVVSYNNERVTFRKLMGCHMHEE 145 Query: 179 PLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVV 238 L F+ + GVLGM G+ + + ++VF++ + GGE++ Sbjct: 146 SL--FLYQQATGVLGMSLSKPQ--GIPTFVNLLFDNAPQLKQVFTICISEN----GGELI 197 Query: 239 LGGSDPQH 246 GG DP + Sbjct: 198 AGGYDPAY 205 >3EMY-A nrPDB Length = 329 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 78/339 (23%), Positives = 135/339 (39%), Gaps = 25/339 (7%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLY-- 128 ++P ++ +++Y + IGTP Q + FDTGS++LWV S++ + A G H++Y Sbjct: 4 SAPNHPSDSADSEYITSVSIGTPAQVLPLDFDTGSSDLWVFSSETPK-SSATG-HAIYTP 61 Query: 129 ESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAK 187 S +S + S + G + D VT+GG +V TQ T + Sbjct: 62 SKSSTSKKVSGASWSISYGDGSSSSGDVYTDKVTIGGFSVNTQGVESATRVSTEFVQDTV 121 Query: 188 FDGVLGMGFPAQAVGGVTPV---FDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDP 244 G++G+ F + P F + S L E +F+ G + G G D Sbjct: 122 ISGLVGLAFDSGNQVRPHPQKTWFSNAASS--LAEPLFTADLRHGQN---GSYNFGYIDT 176 Query: 245 QHYQGNFHYVSISKTDS-WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLI 303 +G Y + + W+ T G SVG L + DTG++ + + + Sbjct: 177 SVAKGPVAYTPVDNSQGFWEFTASGYSVGGGK-LNRNSIDGIADTGTTLLLLDDNVVDAY 235 Query: 304 MQALGAK--EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLA 361 + + + + E V +C + LP SF +G T+ L C Sbjct: 236 YANVQSAQYDNQQEGVVFDCDE--DLPSFSFGVGSSTITIPGDLLNLTPLEEGSSTCFGG 293 Query: 362 LHAMDIPPPTG-PVWVLGATFIRKFYTEFDRHNNRIGFA 399 L + +G + + G ++ FD N R+G+A Sbjct: 294 LQSS-----SGIGINIFGDVALKAALVVFDLGNERLGWA 327 >2QAE-A nrPDB Length = 468 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Query: 120 LACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELP 179 L G+ L++ + + Y GS T H S RV G + + T+ T E TELP Sbjct: 95 LTGGVEYLFKKNKVTYYKGEGSFETAH--SIRVNGLDGKQEMLETKKTIIATGSEPTELP 152 Query: 180 LIPF 183 +PF Sbjct: 153 FLPF 156 >3RRA-A nrPDB Length = 405 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 24/112 (21%), Positives = 46/112 (41%), Gaps = 5/112 (4%) Query: 127 LYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQT----FGEVTELPLIP 182 L E +++ + + + I G F + + GG+++ Q G +TE I Sbjct: 214 LAEQAETYARLAAHTHLPIAAGERMFSRFDFKRVLEAGGVSILQPDLSHAGGITECVKIA 273 Query: 183 FMLAKFDGVLGMGFPAQAVGGVTPV-FDHILSQGVLKEEVFSVYYNRGSHLL 233 M +D L P + + D + L+E+ ++YN+G+ LL Sbjct: 274 AMAEAYDVALAPHCPLGPIALAACLHVDFVSWNATLQEQSMGIHYNKGAELL 325 >3UVA-A nrPDB Length = 424 Score = 28.1 bits (61), Expect = 6.5, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 332 FDLGGRAYTLSSTDYVLQYPNRRDKLCTL 360 F +G +Y + S ++ L Y + DKLC L Sbjct: 235 FGIGSESYVVGSHEFYLSYALKNDKLCLL 263 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5MKT-A nrPDB 552 e-157 5MLG-A nrPDB 523 e-149 4AMT-A nrPDB 507 e-144 5UX4-A nrPDB 494 e-140 1SMR-A nrPDB 459 e-129 2PSG-A nrPDB 440 e-124 3VCM-A nrPDB 439 e-123 5NFG-A nrPDB 436 e-123 1TZS-A nrPDB 420 e-118 1PSO-E nrPDB 400 e-112 4PEP-A nrPDB 397 e-111 4AA9-A nrPDB 396 e-111 4CMS-A nrPDB 395 e-110 5N71-A nrPDB 394 e-110 1AM5-A nrPDB 383 e-107 1MIQ-A nrPDB 374 e-104 1FMX-A nrPDB 373 e-104 1AVF-A nrPDB 371 e-103 2BJU-A nrPDB 371 e-103 3QS1-A nrPDB 368 e-102 5BWY-A nrPDB 368 e-102 2ANL-A nrPDB 363 e-101 1QS8-A nrPDB 363 e-101 5JOD-A nrPDB 360 e-100 1XDH-A nrPDB 359 1e-99 5I70-B nrPDB 352 2e-97 3QVI-A nrPDB 338 2e-93 3FNT-A nrPDB 330 9e-91 4OC6-B nrPDB 312 1e-85 1QDM-A nrPDB 310 9e-85 1B5F-A nrPDB 283 7e-77 1UH8-A nrPDB 273 8e-74 2QZW-A nrPDB 272 2e-73 3LIZ-A nrPDB 266 8e-72 2ASI-A nrPDB 265 3e-71 3PVK-A nrPDB 264 6e-71 2H6T-A nrPDB 262 2e-70 1J71-A nrPDB 256 1e-68 1MPP-A nrPDB 253 8e-68 4Y9W-A nrPDB 252 2e-67 3TPL-A nrPDB 247 6e-66 3FV3-A nrPDB 247 7e-66 2QZX-A nrPDB 246 2e-65 3ZKX-A nrPDB 240 9e-64 4B1C-A nrPDB 234 7e-62 1IBQ-A nrPDB 231 6e-61 3O9L-A nrPDB 229 2e-60 1PPK-E nrPDB 225 3e-59 5HCT-A nrPDB 222 2e-58 3OAD-B nrPDB 218 4e-57 3EMY-A nrPDB 218 4e-57 1IZE-A nrPDB 217 5e-57 3PI0-A nrPDB 211 4e-55 1WKR-A nrPDB 207 6e-54 4OD9-A nrPDB 147 1e-35 4ZL4-A nrPDB 142 3e-34 1B5F-B nrPDB 111 7e-25 Sequences not found previously or not previously below threshold: 4PPH-A nrPDB 53 2e-07 3AUP-A nrPDB 50 2e-06 1T6G-A nrPDB 42 3e-04 3HD8-A nrPDB 40 0.002 3Q31-A nrPDB 33 0.31 2BKL-A nrPDB 32 0.41 3VLB-A nrPDB 32 0.55 5U47-A nrPDB 32 0.58 3OS6-A nrPDB 32 0.69 2D81-A nrPDB 30 2.3 5B8F-A nrPDB 30 2.3 5OR1-A nrPDB 30 2.6 5I24-A nrPDB 30 2.6 3SOK-A nrPDB 29 3.5 1IGA-A nrPDB 28 5.1 4XVZ-A nrPDB 28 7.4 >5MKT-A nrPDB Length = 389 Score = 552 bits (1422), Expect = e-157, Method: Composition-based stats. Identities = 381/381 (100%), Positives = 381/381 (100%) Query: 22 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 81 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN Sbjct: 1 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 60 Query: 82 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 141 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS Sbjct: 61 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 120 Query: 142 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 201 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV Sbjct: 121 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 180 Query: 202 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS 261 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS Sbjct: 181 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS 240 Query: 262 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC 321 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC Sbjct: 241 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC 300 Query: 322 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF 381 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF Sbjct: 301 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF 360 Query: 382 IRKFYTEFDRHNNRIGFALAR 402 IRKFYTEFDRHNNRIGFALAR Sbjct: 361 IRKFYTEFDRHNNRIGFALAR 381 >5MLG-A nrPDB Length = 389 Score = 523 bits (1346), Expect = e-149, Method: Composition-based stats. Identities = 323/381 (84%), Positives = 342/381 (89%) Query: 22 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 81 LPT TA+F RI LKKMPSVREILEERGVDMTR+SAEWG F K+ S TN+TSPVVLTNYL+ Sbjct: 1 LPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGEFIKKSSFTNVTSPVVLTNYLD 60 Query: 82 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 141 TQYYGEIGIGTP QTFKVIFDTGSANLWVPSTKC LY AC IH+LY+SS+SSSYMENG+ Sbjct: 61 TQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYMENGT 120 Query: 142 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 201 +FTIHYGSG+VKGFLSQD VTVGGI VTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV Sbjct: 121 EFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 180 Query: 202 GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDS 261 GV PVFDHILSQ VLKEEVFSVYY+R SHLLGGEVVLGGSDPQHYQGNFHYVSISK S Sbjct: 181 DGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLGGSDPQHYQGNFHYVSISKAGS 240 Query: 262 WQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNC 321 WQITMKGVSVG +TLLCEEGC VVDTG+S+IS PTSSL+LIMQALG KEKR YVVNC Sbjct: 241 WQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVNC 300 Query: 322 SQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATF 381 SQVPTLPDISF LGGR YTLS+ DYV + P R D LC LAL +DIPPPTGPVWVLGATF Sbjct: 301 SQVPTLPDISFYLGGRTYTLSNMDYVQKNPFRNDDLCILALQGLDIPPPTGPVWVLGATF 360 Query: 382 IRKFYTEFDRHNNRIGFALAR 402 IRKFYTEFDRHNNRIGFALAR Sbjct: 361 IRKFYTEFDRHNNRIGFALAR 381 >4AMT-A nrPDB Length = 383 Score = 507 bits (1306), Expect = e-144, Method: Composition-based stats. Identities = 269/384 (70%), Positives = 319/384 (83%), Gaps = 4/384 (1%) Query: 22 LPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLN 81 LPT T TF+RI LK+MPS+RE L+ERGVDM RL EW KR +L N TS V+LTNY++ Sbjct: 1 LPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMD 60 Query: 82 TQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGS 141 TQYYGEIGIGTPPQTFKV+FDTGS+N+WVPS+KCSRLY AC H L+++SDSSSY NG+ Sbjct: 61 TQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGT 120 Query: 142 DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAV 201 + T+ Y +G V GFLSQD +TVGGITVTQ FGEVTE+P +PFMLA+FDGV+GMGF QA+ Sbjct: 121 ELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAI 180 Query: 202 GGVTPVFDHILSQGVLKEEVFSVYYNR---GSHLLGGEVVLGGSDPQHYQGNFHYVSISK 258 G VTP+FD+I+SQGVLKE+VFS YYNR S LGG++VLGGSDPQHY+GNFHY+++ K Sbjct: 181 GRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIK 240 Query: 259 TDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYV 318 T WQI MKGVSVGSSTLLCE+GC +VDTG+S+IS TSS++ +M+ALGAK KR+ +YV Sbjct: 241 TGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAK-KRLFDYV 299 Query: 319 VNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLG 378 V C++ PTLPDISF LGG+ YTL+S DYV Q KLCTLA+HAMDIPPPTGP W LG Sbjct: 300 VKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALG 359 Query: 379 ATFIRKFYTEFDRHNNRIGFALAR 402 ATFIRKFYTEFDR NNRIGFALAR Sbjct: 360 ATFIRKFYTEFDRRNNRIGFALAR 383 >5UX4-A nrPDB Length = 420 Score = 494 bits (1271), Expect = e-140, Method: Composition-based stats. Identities = 176/404 (43%), Positives = 248/404 (61%), Gaps = 14/404 (3%) Query: 9 WALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTK-RPSL 67 W+ + L+ S+ T + RIPL+K S+R + E G + L + + S Sbjct: 3 WSWVFLF---FLSVTTGVHSLIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSS 59 Query: 68 TNLTSPVV--LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIH 125 PV L NYL+ QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC +H Sbjct: 60 PRTKEPVSELLKNYLDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVH 119 Query: 126 SLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTV------GGITV-TQTFGEVTEL 178 Y S SS+Y++NG+ F IHYGSG + G+LSQD+V+V GGI V Q FGE T+ Sbjct: 120 HKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQ 179 Query: 179 PLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGS-HLLGGEV 237 P + F+ AKFDG+LGMG+P +V V PVFD+++ Q ++++ +FS Y NR GGE+ Sbjct: 180 PGVVFIAAKFDGILGMGYPFISVNNVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGEL 239 Query: 238 VLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPT 297 +LGG+D ++Y G Y+++++ WQ+ M + VGS LC+ GC +VDTG+S + P Sbjct: 240 MLGGTDSRYYHGELSYLNVTRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPV 299 Query: 298 SSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 +K + +A+GA EY++ C +V +LP I+F LGG+ Y L Y+L+ + Sbjct: 300 DEVKELQKAIGAVPLIQGEYMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTI 359 Query: 358 CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 C MDIPPP+GP+W+LG FI +YT FDR NR+GFA A Sbjct: 360 CLSGFMGMDIPPPSGPLWILGDVFIGCYYTVFDREYNRVGFAKA 403 >1SMR-A nrPDB Length = 335 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 319/335 (95%), Positives = 330/335 (98%) Query: 68 TNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSL 127 T+L SPVVLTNYLN+QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSL Sbjct: 1 TDLISPVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSL 60 Query: 128 YESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAK 187 YESSDSSSYMENG DFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVT+LPLIPFMLA+ Sbjct: 61 YESSDSSSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTQLPLIPFMLAQ 120 Query: 188 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHY 247 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKE+VFSVYYNRG HLLGGEVVLGGSDPQHY Sbjct: 121 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHLLGGEVVLGGSDPQHY 180 Query: 248 QGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQAL 307 QG+FHYVS+SKTDSWQITMKGVSVGSSTLLCEEGC VVVDTGSSFISAPTSSLKLIMQAL Sbjct: 181 QGDFHYVSLSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQAL 240 Query: 308 GAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDI 367 GAKEKR+ EYVV+CSQVPTLPDISF+LGGRAYTLSSTDYVLQYPNRRDKLCT+ALHAMDI Sbjct: 241 GAKEKRLHEYVVSCSQVPTLPDISFNLGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDI 300 Query: 368 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR Sbjct: 301 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 335 >2PSG-A nrPDB Length = 370 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 149/376 (39%), Positives = 216/376 (57%), Gaps = 10/376 (2%) Query: 29 FERIPLKKMPSVREILEERGV--DMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYG 86 ++PL + S+R+ L + G D + P L L NYL+T+Y+G Sbjct: 1 LVKVPLVRKKSLRQNLIKDGKLKDFLKTHKHNPASKYFPEAAALIGDEPLENYLDTEYFG 60 Query: 87 EIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIH 146 IGIGTP Q F VIFDTGS+NLWVPS CS L AC H+ + DSS++ + +I Sbjct: 61 TIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNPDDSSTFEATSQELSIT 118 Query: 147 YGSGRVKGFLSQDSVTVGGIT-VTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVT 205 YG+G + G L D+V VGGI+ Q FG P A FDG+LG+ +P+ + G T Sbjct: 119 YGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGAT 178 Query: 206 PVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQIT 265 PVFD++ QG++ +++FSVY + G V+LGG D +Y G+ ++V +S WQIT Sbjct: 179 PVFDNLWDQGLVSQDLFSVYLSSNDDS-GSVVLLGGIDSSYYTGSLNWVPVSVEGYWQIT 237 Query: 266 MKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVP 325 + +++ T+ C GC +VDTG+S ++ PTS++ I +GA E E V++CS + Sbjct: 238 LDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSID 297 Query: 326 TLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKF 385 +LPDI F + G Y LS + Y+LQ D CT MD+P +G +W+LG FIR++ Sbjct: 298 SLPDIVFTIDGVQYPLSPSAYILQ----DDDSCTSGFEGMDVPTSSGELWILGDVFIRQY 353 Query: 386 YTEFDRHNNRIGFALA 401 YT FDR NN++G A Sbjct: 354 YTVFDRANNKVGLAPV 369 >3VCM-A nrPDB Length = 335 Score = 439 bits (1128), Expect = e-123, Method: Composition-based stats. Identities = 241/337 (71%), Positives = 287/337 (85%), Gaps = 3/337 (0%) Query: 66 SLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIH 125 +L N TS V+LTNY++TQYYGEIGIGTPPQTFKV+FDTGS+N+WVPS+KCSRLY AC H Sbjct: 2 TLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYH 61 Query: 126 SLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFML 185 L+++SDSSSY NG++ T+ Y +G V GFLSQD +TVGGITVTQ FGEVTE+P +PFML Sbjct: 62 KLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFML 121 Query: 186 AKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQ 245 A+FDGV+GMGF QA+G VTP+FD+I+SQGVLKE+VFS YYNR S LGG++VLGGSDPQ Sbjct: 122 AEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDS--LGGQIVLGGSDPQ 179 Query: 246 HYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQ 305 HY+GNFHY+++ KT WQI MKGVSVGSSTLLCE+GC +VDTG+S+IS TSS++ +M+ Sbjct: 180 HYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLME 239 Query: 306 ALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAM 365 ALGAK KR+ +YVV C++ PTLPDISF LGG+ YTL+S DYV Q KLCTLA+HAM Sbjct: 240 ALGAK-KRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAM 298 Query: 366 DIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 DIPPPTGP W LGATFIRKFYTEFDR NNRIGFALAR Sbjct: 299 DIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 335 >5NFG-A nrPDB Length = 383 Score = 436 bits (1122), Expect = e-123, Method: Composition-based stats. Identities = 160/379 (42%), Positives = 226/379 (59%), Gaps = 9/379 (2%) Query: 29 FERIPLKKMPSVR-EILEERGVDMTRLSAEWGVFTKRPSLTNLTSP-VVLTNYLNTQYYG 86 R+ LKK R + L GV M L F R +L + S V LTN +T YYG Sbjct: 7 LLRVGLKKRKVDRLDQLRAHGVHM--LGNARKDFGFRRTLRDSGSGIVALTNDRDTAYYG 64 Query: 87 EIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIH 146 EIGIGTPPQ F VIFDTGS++LWVPSTKC LAC IH Y+S DSS+Y NG+ +I Sbjct: 65 EIGIGTPPQNFAVIFDTGSSDLWVPSTKCDTS-LACVIHPRYDSGDSSTYKGNGTTASIQ 123 Query: 147 YGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVT 205 YG+G + GF SQDSV VG + V Q F E TE F+ ++FDG+LG+GF + G Sbjct: 124 YGTGAIVGFYSQDSVEVGDLVVEHQDFIETTEEDDTVFLKSEFDGILGLGFQEISAGKAV 183 Query: 206 PVFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQI 264 PV+ ++++QG+++E VFS + NR GGE+V GG DP H++GN YV +++ WQ Sbjct: 184 PVWYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNHFRGNHTYVPVTRKGYWQF 243 Query: 265 TMKGVSVGS-STLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKR-IEEYVVNCS 322 M V +G S+ C GCA + D+G+SF + PT+ + I QA+GAK E +V+C+ Sbjct: 244 EMGDVLIGDKSSGFCAGGCAAIADSGTSFFAGPTAIITQINQAIGAKGGGGSAESIVDCN 303 Query: 323 QVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFI 382 + ++P+I+F +G + + ++ Y+ + C A+DI P GP+W+LG F+ Sbjct: 304 GISSMPNIAFTIGSKLFEVTPEQYIYKVGEGEAATCISGFTALDIMSPQGPIWILGDMFM 363 Query: 383 RKFYTEFDRHNNRIGFALA 401 ++T FD R+GFA A Sbjct: 364 GPYHTVFDYGKLRVGFAEA 382 >1TZS-A nrPDB Length = 351 Score = 420 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 145/335 (43%), Positives = 211/335 (62%), Gaps = 5/335 (1%) Query: 69 NLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLY 128 + ++ L NYL+ +Y+G I IG+PPQ F VIFDTGS+NLWVPS C+ AC HS + Sbjct: 10 DQSAKEPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYCTSP--ACKTHSRF 67 Query: 129 ESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAK 187 + S SS+Y + G F+I YG+G + G + D V+V G+TV Q FGE P F+ A+ Sbjct: 68 QPSQSSTYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAE 127 Query: 188 FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQH 246 FDG+LG+G+P+ AVGGVTPVFD++++Q ++ +FSVY + G E++ GG D H Sbjct: 128 FDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSH 187 Query: 247 YQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQA 306 + G+ ++V ++K WQI + + VG + + C EGC +VDTG+S I+ P+ +K + A Sbjct: 188 FSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNA 247 Query: 307 LGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMD 366 +GA EY V C+ + +PD++F + G YTLS T Y L + C+ +D Sbjct: 248 IGAAPV-DGEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLD 306 Query: 367 IPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 I PP GP+W+LG FIR+FY+ FDR NNR+G A A Sbjct: 307 IHPPAGPLWILGDVFIRQFYSVFDRGNNRVGLAPA 341 >1PSO-E nrPDB Length = 326 Score = 400 bits (1027), Expect = e-112, Method: Composition-based stats. Identities = 132/328 (40%), Positives = 195/328 (59%), Gaps = 8/328 (2%) Query: 75 VLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSS 134 L NYL+ +Y+G IGIGTP Q F V+FDTGS+NLWVPS CS L AC H+ + DSS Sbjct: 5 PLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSL--ACTNHNRFNPEDSS 62 Query: 135 SYMENGSDFTIHYGSGRVKGFLSQDSVTVGGIT-VTQTFGEVTELPLIPFMLAKFDGVLG 193 +Y +I YG+G + G L D+V VGGI+ Q FG P A FDG+LG Sbjct: 63 TYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILG 122 Query: 194 MGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHY 253 + +P+ + G TPVFD+I +QG++ +++FSVY + G V+ GG D +Y G+ ++ Sbjct: 123 LAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQS-GSVVIFGGIDSSYYTGSLNW 181 Query: 254 VSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKR 313 V ++ WQIT+ +++ + C EGC +VDTG+S ++ PTS + I +GA E Sbjct: 182 VPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENS 241 Query: 314 IEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGP 373 + VV+CS + +LPDI F + G Y + + Y+LQ + C M++P +G Sbjct: 242 DGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPTESGE 297 Query: 374 VWVLGATFIRKFYTEFDRHNNRIGFALA 401 +W+LG FIR+++T FDR NN++G A Sbjct: 298 LWILGDVFIRQYFTVFDRANNQVGLAPV 325 >4PEP-A nrPDB Length = 326 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 140/332 (42%), Positives = 200/332 (60%), Gaps = 8/332 (2%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYES 130 L NYL+T+Y+G IGIGTP Q F VIFDTGS+NLWVPS CS L AC H+ + Sbjct: 1 IGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSL--ACSDHNQFNP 58 Query: 131 SDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGIT-VTQTFGEVTELPLIPFMLAKFD 189 DSS++ + +I YG+G + G L D+V VGGI+ Q FG P A FD Sbjct: 59 DDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFD 118 Query: 190 GVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQG 249 G+LG+ +P+ + G TPVFD++ QG++ +++FSVY + G V+LGG D +Y G Sbjct: 119 GILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDS-GSVVLLGGIDSSYYTG 177 Query: 250 NFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA 309 + ++V +S WQIT+ +++ T+ C GC +VDTG+S ++ PTS++ I +GA Sbjct: 178 SLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGA 237 Query: 310 KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPP 369 E E V++CS + +LPDI F + G Y LS + Y+LQ D CT MD+P Sbjct: 238 SENSDGEMVISCSSIDSLPDIVFTIDGVQYPLSPSAYILQ----DDDSCTSGFEGMDVPT 293 Query: 370 PTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 +G +W+LG FIR++YT FDR NN++G A Sbjct: 294 SSGELWILGDVFIRQYYTVFDRANNKVGLAPV 325 >4AA9-A nrPDB Length = 320 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 126/329 (38%), Positives = 191/329 (58%), Gaps = 13/329 (3%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDS 133 LT+YL++QY+G+I IGTPPQ F V+FDTGS++LWVPS C C H ++ S Sbjct: 3 EPLTSYLDSQYFGKIYIGTPPQEFTVVFDTGSSDLWVPSIYCKSN--VCKNHHRFDPRKS 60 Query: 134 SSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVL 192 S++ G +IHYG+G ++GFL D+VTV I QT G TE P F ++FDG+L Sbjct: 61 STFRNLGKPLSIHYGTGSMEGFLGYDTVTVSNIVDPNQTVGLSTEQPGEVFTYSEFDGIL 120 Query: 193 GMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFH 252 G+ +P+ A PVFD+++ + ++ ++FSVY +R G + LG DP +Y G+ H Sbjct: 121 GLAYPSLASEYSVPVFDNMMDRHLVARDLFSVYMDRNGQ--GSMLTLGAIDPSYYTGSLH 178 Query: 253 YVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEK 312 +V ++ WQ T+ V++ + C GC ++DTG+S + P+S + I A+GA E Sbjct: 179 WVPVTLQQYWQFTVDSVTINGVAVACVGGCQAILDTGTSVLFGPSSDILKIQMAIGATEN 238 Query: 313 RIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTG 372 R E+ VNC + ++P + F++ GR Y LS + Y ++ CT Sbjct: 239 RYGEFDVNCGNLRSMPTVVFEINGRDYPLSPSAYT----SKDQGFCTSGFQG----DNNS 290 Query: 373 PVWVLGATFIRKFYTEFDRHNNRIGFALA 401 +W+LG FIR++Y+ FDR NNR+G A A Sbjct: 291 ELWILGDVFIREYYSVFDRANNRVGLAKA 319 >4CMS-A nrPDB Length = 323 Score = 395 bits (1015), Expect = e-110, Method: Composition-based stats. Identities = 122/333 (36%), Positives = 193/333 (57%), Gaps = 13/333 (3%) Query: 70 LTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYE 129 + V LTNYL++QY+G+I +GTPPQ F V+FDTGS++ WVPS C AC H ++ Sbjct: 2 EVASVPLTNYLDSQYFGKIYLGTPPQEFTVLFDTGSSDFWVPSIYCKSN--ACKNHQRFD 59 Query: 130 SSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGIT-VTQTFGEVTELPLIPFMLAKF 188 SS++ G +IHYG+G ++G L D+VTV I + QT G T+ P F A+F Sbjct: 60 PRKSSTFQNLGKPLSIHYGTGSMQGILGYDTVTVSNIVDIQQTVGLSTQEPGDVFTYAEF 119 Query: 189 DGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQ 248 DG+LGM +P+ A PVFD+++++ ++ +++FSVY +R + LG DP +Y Sbjct: 120 DGILGMAYPSLASEYSIPVFDNMMNRHLVAQDLFSVYMDRNGQE--SMLTLGAIDPSYYT 177 Query: 249 GNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALG 308 G+ H+V ++ WQ T+ V++ + CE GC ++DTG+S + P+S + I QA+G Sbjct: 178 GSLHWVPVTVQQYWQFTVDSVTISGVVVACEGGCQAILDTGTSKLVGPSSDILNIQQAIG 237 Query: 309 AKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIP 368 A + + E+ ++C + +P + F++ G+ Y L+ + Y Q CT + Sbjct: 238 ATQNQYGEFDIDCDNLSYMPTVVFEINGKMYPLTPSAYTSQ----DQGFCTSGFQS---- 289 Query: 369 PPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 W+LG FIR++Y+ FDR NN +G A A Sbjct: 290 ENHSQKWILGDVFIREYYSVFDRANNLVGLAKA 322 >5N71-A nrPDB Length = 345 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 141/337 (41%), Positives = 209/337 (62%), Gaps = 13/337 (3%) Query: 73 PVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSD 132 P L N L+ YYG I IGTPPQ F+VIFDTGSANLW+PS+KC+ Y C H Y+SS Sbjct: 7 PEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTKY--CLHHHRYDSSK 64 Query: 133 SSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGV 191 SS+Y +G +FTI YGSG V+GF+S+D +G V+ Q GE + + A FDG+ Sbjct: 65 SSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKVSGQPLGEALVVGGESLLEAPFDGI 124 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVL-KEEVFSVYYNRGSHL-LGGEVVLGGSDPQHYQG 249 LG+ +P+ AV GV PVFD+++ QG+L ++ VFSVY NR GGEV+ GG D HY+G Sbjct: 125 LGLAYPSIAVDGVVPVFDNMMKQGLLGEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKG 184 Query: 250 NFHYVSISKTDSWQITMKGVSVGSST-----LLCEEGCAVVVDTGSSFISAPTSSLKLIM 304 + YV ++ WQ + GV S++ LLC++GC + +TG+S I+ P + + Sbjct: 185 SITYVPVTAKGYWQFHVDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGPPEEVDSLN 244 Query: 305 QALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHA 364 Q LG + +Y+++C ++ +LP+++F + G+ ++L S DYVL+ + LC Sbjct: 245 QYLGGTKTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVSGFMG 304 Query: 365 MDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 +++P P+W+LG F+ +YT FDR +R+GFA Sbjct: 305 LEMPQ---PLWILGDVFLGPYYTIFDRDQDRVGFAEV 338 >1AM5-A nrPDB Length = 324 Score = 383 bits (984), Expect = e-107, Method: Composition-based stats. Identities = 135/327 (41%), Positives = 198/327 (60%), Gaps = 10/327 (3%) Query: 76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 135 + N +T+YYG I IGTPP++FKVIFDTGS+NLWV S+ CS AC H+ ++ SS+ Sbjct: 6 MKNEADTEYYGVISIGTPPESFKVIFDTGSSNLWVSSSHCS--AQACSNHNKFKPRQSST 63 Query: 136 YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGM 194 Y+E G + YG+G ++G L QD+V+VGG + Q GE P A FDG+LG+ Sbjct: 64 YVETGKTVDLTYGTGGMRGILGQDTVSVGGGSDPNQELGESQTEPGPFQAAAPFDGILGL 123 Query: 195 GFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYV 254 +P+ A G PVFD++ SQ ++++++FS Y + G G EV+LGG D HY G+ H++ Sbjct: 124 AYPSIAAAGAVPVFDNMGSQSLVEKDLFSFYLS-GGGANGSEVMLGGVDNSHYTGSIHWI 182 Query: 255 SISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRI 314 ++ WQ+ + G++V T C EGC +VDTG+S I AP S+L IM+ +GA E Sbjct: 183 PVTAEKYWQVALDGITVNGQTAAC-EGCQAIVDTGTSKIVAPVSALANIMKDIGASEN-Q 240 Query: 315 EEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPV 374 E + NC+ V +LPDI+F + G L + Y+ CT L + +P T + Sbjct: 241 GEMMGNCASVQSLPDITFTINGVKQPLPPSAYI----EGDQAFCTSGLGSSGVPSNTSEL 296 Query: 375 WVLGATFIRKFYTEFDRHNNRIGFALA 401 W+ G F+R +YT +DR NN++GFA A Sbjct: 297 WIFGDVFLRNYYTIYDRTNNKVGFAPA 323 >1MIQ-A nrPDB Length = 375 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 115/345 (33%), Positives = 181/345 (52%), Gaps = 14/345 (4%) Query: 61 FTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYL 120 + K+ L + + L + N +YGE +G Q F +IFDTGSANLWVPS KC+ Sbjct: 41 YMKQNYLGSENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSS-- 98 Query: 121 ACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPL 180 C I +LY+SS S SY ++G+ I YGSG VKGF S+D VT+G +++ F EVT+ Sbjct: 99 GCSIKNLYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVTLGHLSMPYKFIEVTDTDD 158 Query: 181 IP--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVV 238 + + +FDG+LG+G+ ++G + P+ + +Q + +F+ Y + G + Sbjct: 159 LEPIYSSVEFDGILGLGWKDLSIGSIDPIVVELKNQNKIDNALFTFYLPVHD-VHAGYLT 217 Query: 239 LGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTS 298 +GG + + Y+GN Y ++ WQI + V G T+ E V+VD+G++ I+AP+ Sbjct: 218 IGGIEEKFYEGNITYEKLNHDLYWQIDLD-VHFGKQTM---EKANVIVDSGTTTITAPSE 273 Query: 299 SLKLIMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 L L K + YV C +P + F YTL Y+ D L Sbjct: 274 FLNKFFANLNVIKVPFLPFYVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTL 332 Query: 358 CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C + + +DI T ++LG F+RK++T FD +GFA+A+ Sbjct: 333 CMITMLPVDIDSNT---FILGDPFMRKYFTVFDYDKESVGFAIAK 374 >1FMX-A nrPDB Length = 329 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 128/332 (38%), Positives = 195/332 (58%), Gaps = 10/332 (3%) Query: 73 PVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSD 132 V LTNYLN QYY +I +GTPPQ FKVI DTGS+NLWVPS +C L AC +HS Y+ Sbjct: 4 DVPLTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSNECGSL--ACFLHSKYDHEA 61 Query: 133 SSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGV 191 SSSY NG++F I YG+G ++G++SQD++++G +T+ Q F E T P + F KFDG+ Sbjct: 62 SSSYKANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATSEPGLTFAFGKFDGI 121 Query: 192 LGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYY--NRGSHLLGGEVVLGGSDPQHYQG 249 LG+G+ +V V P F + + Q +L E+ F+ Y GGE GG D ++G Sbjct: 122 LGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFGGIDESKFKG 181 Query: 250 NFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA 309 + ++ + + W++ +G+ +G E A + DTG+S I+ P+ ++I +GA Sbjct: 182 DITWLPVRRKAYWEVKFEGIGLGDEYAELESHGAAI-DTGTSLITLPSGLAEMINAEIGA 240 Query: 310 KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPP 369 K+ +Y ++C+ LPD+ F+ G +T+ DY L+ C A+ MD P Sbjct: 241 KKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGPYDYTLEVSGS----CISAITPMDFPE 296 Query: 370 PTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 P GP+ ++G F+RK+Y+ +D NN +G A A Sbjct: 297 PVGPLAIVGDAFLRKYYSIYDLGNNAVGLAKA 328 >1AVF-A nrPDB Length = 329 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 124/326 (38%), Positives = 187/326 (57%), Gaps = 9/326 (2%) Query: 79 YLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYME 138 Y++ Y+GEI IGTPPQ F V+FDTGS+NLWVPS C AC HS + S+SS+Y Sbjct: 9 YMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQ--ACTSHSRFNPSESSTYST 66 Query: 139 NGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFP 197 NG F++ YGSG + GF D++TV I V Q FG P F+ A+FDG++G+ +P Sbjct: 67 NGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYP 126 Query: 198 AQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSIS 257 A +V T ++ +G L VFSVY + GG VV GG D Y G ++ ++ Sbjct: 127 ALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVT 186 Query: 258 KTDSWQITMKGVSVGSS-TLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEE 316 + WQI ++ +G + C EGC +VDTG+S ++ P + ++QA GA+E + Sbjct: 187 QELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQ 246 Query: 317 YVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTG-PVW 375 ++VNC+ + LP ++F + G + L + Y+L + CT+ + + G P+W Sbjct: 247 FLVNCNSIQNLPSLTFIINGVEFPLPPSSYIL----SNNGYCTVGVEPTYLSSQNGQPLW 302 Query: 376 VLGATFIRKFYTEFDRHNNRIGFALA 401 +LG F+R +Y+ +D NNR+GFA A Sbjct: 303 ILGDVFLRSYYSVYDLGNNRVGFATA 328 >2BJU-A nrPDB Length = 453 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 111/347 (31%), Positives = 174/347 (50%), Gaps = 12/347 (3%) Query: 58 WGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSR 117 TK L + + L ++ N +YG+ +G Q F I DTGSANLWVPS KC+ Sbjct: 114 NSGLTKTNYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT 173 Query: 118 LYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTE 177 C LY+SS S +Y ++G+ ++Y SG V GF S+D VTVG +++ F EV + Sbjct: 174 --AGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVID 231 Query: 178 LPLIP--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGG 235 + + FDG+LG+G+ ++G V P+ + +Q ++ +F+ Y G Sbjct: 232 TNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDK-HTG 290 Query: 236 EVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISA 295 + +GG + + Y+G Y ++ WQIT+ VG+ L E +VD+G+S I+ Sbjct: 291 FLTIGGIEERFYEGPLTYEKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITV 346 Query: 296 PTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRD 355 PT L ++Q L + + V LP F YTL Y+ + Sbjct: 347 PTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGP 406 Query: 356 KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 LC L + +D P PT ++LG F+RK++T FD N+ +G ALA+ Sbjct: 407 GLCMLNIIGLDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAK 450 >3QS1-A nrPDB Length = 336 Score = 368 bits (945), Expect = e-102, Method: Composition-based stats. Identities = 115/344 (33%), Positives = 185/344 (53%), Gaps = 14/344 (4%) Query: 62 TKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA 121 T++P L N V L + N YYGE IG Q F IFDTGSANLWVPS +C+ + Sbjct: 1 TQKPHLGNAGDSVTLNDVANVMYYGEAQIGDNKQKFAFIFDTGSANLWVPSAQCNT--IG 58 Query: 122 CGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLI 181 C +LY+S+ S +Y ++G+ ++Y SG V GF S+D VT+ ++ F EVT+ Sbjct: 59 CKTKNLYDSNKSKTYEKDGTKVEMNYVSGTVSGFFSKDIVTIANLSFPYKFIEVTDTNGF 118 Query: 182 P--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVL 239 + L +FDG++G+G+ ++G V PV + +Q +++ VF+ Y G + + Sbjct: 119 EPAYTLGQFDGIVGLGWKDLSIGSVDPVVVELKNQNKIEQAVFTFYLPFDDK-HKGYLTI 177 Query: 240 GGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSS 299 GG + + Y+G Y ++ WQ+ + + G+ T+ E +VD+G+S I+APT Sbjct: 178 GGIEDRFYEGQLTYEKLNHDLYWQVDLD-LHFGNLTV---EKATAIVDSGTSSITAPTEF 233 Query: 300 LKLIMQALG-AKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLC 358 L + L K + Y+ C+ P LP + F YTL Y+ Q + LC Sbjct: 234 LNKFFEGLDVVKIPFLPLYITTCNN-PKLPTLEFRSATNVYTLEPEYYLQQIFDFGISLC 292 Query: 359 TLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 +++ +D+ T ++LG F+RK++T FD N+ +GFALA+ Sbjct: 293 MVSIIPVDLNKNT---FILGDPFMRKYFTVFDYDNHTVGFALAK 333 >5BWY-A nrPDB Length = 376 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 111/347 (31%), Positives = 174/347 (50%), Gaps = 12/347 (3%) Query: 58 WGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSR 117 TK L + + L ++ N +YG+ +G Q F I DTGSANLWVPS KC+ Sbjct: 37 NSGLTKTNYLGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT 96 Query: 118 LYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTE 177 C LY+SS S +Y ++G+ ++Y SG V GF S+D VTVG +++ F EV + Sbjct: 97 --AGCLTKHLYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVID 154 Query: 178 LPLIP--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGG 235 + + FDG+LG+G+ ++G V P+ + +Q ++ +F+ Y G Sbjct: 155 TNGFEPTYTASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDK-HTG 213 Query: 236 EVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISA 295 + +GG + + Y+G Y ++ WQIT+ VG+ L E +VD+G+S I+ Sbjct: 214 FLTIGGIEERFYEGPLTYEKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITV 269 Query: 296 PTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRD 355 PT L ++Q L + + V LP F YTL Y+ + Sbjct: 270 PTDFLNKMLQNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGP 329 Query: 356 KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 LC L + +D P PT ++LG F+RK++T FD N+ +G ALA+ Sbjct: 330 GLCMLNIIGLDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAK 373 >2ANL-A nrPDB Length = 327 Score = 363 bits (933), Expect = e-101, Method: Composition-based stats. Identities = 112/337 (33%), Positives = 182/337 (54%), Gaps = 14/337 (4%) Query: 69 NLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLY 128 + + L + N +YGE +G Q F +IFDTGSANLWVPS KC+ + C LY Sbjct: 1 SENDVIELDDVANLMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNS--IGCSTKHLY 58 Query: 129 ESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FMLA 186 +SS S SY ++G+ I YGSG V+GF S+D VT+G +++ F EVT+ + + A Sbjct: 59 DSSKSKSYEKDGTKVEITYGSGTVRGFFSKDLVTLGYLSLPYKFIEVTDTDDLEPLYTAA 118 Query: 187 KFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQH 246 +FDG+LG+G+ ++G + P+ + +Q + + +F+ Y G + +GG + + Sbjct: 119 EFDGILGLGWKDLSIGSIDPIVVELKNQNKIDQALFTFYLPVHDK-HSGYLTIGGIEEKF 177 Query: 247 YQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQA 306 Y+G Y ++ WQ+ + V+ G +++ E V+VD+G+S I+APTS + + Sbjct: 178 YEGELTYEKLNHDLFWQVDLD-VNFGKTSM---EKANVIVDSGTSTITAPTSFINKFFKD 233 Query: 307 LGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAM 365 L K + Y+ C+ +P + F YTL Y+ + D LC L + + Sbjct: 234 LNVIKVPFLPFYITTCNN-KDMPTLEFKSANNTYTLEPEYYMEPLLDIDDTLCMLYILPV 292 Query: 366 DIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 DI T ++LG F+RK++T FD IGFA+A+ Sbjct: 293 DIDKNT---FILGDPFMRKYFTVFDYDKESIGFAVAK 326 >1QS8-A nrPDB Length = 329 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 113/339 (33%), Positives = 177/339 (52%), Gaps = 14/339 (4%) Query: 67 LTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHS 126 L + + L + N +YGE +G Q F +IFDTGSANLWVPS KC+ C I + Sbjct: 1 LGSENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSS--GCSIKN 58 Query: 127 LYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FM 184 LY+SS S SY ++G+ I YGSG VKGF S+D VT+G +++ F EV + + + Sbjct: 59 LYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVTLGHLSMPYKFIEVIDTDDLEPIYS 118 Query: 185 LAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDP 244 +FDG+LG+G+ ++G + P+ + +Q + +F+ Y + G + +GG + Sbjct: 119 SVEFDGILGLGWKDLSIGSIDPIVVELKNQNKIDNALFTFYLPVHD-VHAGYLTIGGIEE 177 Query: 245 QHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIM 304 + Y+GN Y ++ WQI + V G T+ E V+VD+G++ I+AP+ L Sbjct: 178 KFYEGNITYEKLNHDLYWQIDLD-VHFGKQTM---EKANVIVDSGTTTITAPSEFLNKFF 233 Query: 305 QALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALH 363 L K + YV C +P + F YTL Y+ D LC + + Sbjct: 234 ANLNVIKVPFLPFYVTTCDN-KEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITML 292 Query: 364 AMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 +DI T ++LG F+RK++T FD +GFA+A+ Sbjct: 293 PVDIDSNT---FILGDPFMRKYFTVFDYDKESVGFAIAK 328 >5JOD-A nrPDB Length = 375 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 109/345 (31%), Positives = 175/345 (50%), Gaps = 14/345 (4%) Query: 61 FTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYL 120 + ++ L + + L + N +YGE IGT Q F IFDTGSANLWVPS C + Sbjct: 40 YAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDS--I 97 Query: 121 ACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPL 180 C LY++S S SY ++G+ I YGSG V+G+ S+D +++G +++ F EVT+ Sbjct: 98 GCSTKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADD 157 Query: 181 IP--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVV 238 + + ++FDG+LG+G+ ++G + PV + Q + +F+ Y G + Sbjct: 158 LEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDK-HVGYLT 216 Query: 239 LGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTS 298 +GG + Y+G Y ++ WQI + + G + + VVD+G+S I+APTS Sbjct: 217 IGGIESDFYEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTS 272 Query: 299 SLKLIMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 L + + K + YV C LP + F YTL Y+ + L Sbjct: 273 FLNKFFRDMNVIKVPFLPLYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPAL 331 Query: 358 CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C L + +DI T ++LG F+RK++T FD +GFA+A+ Sbjct: 332 CMLYILPVDIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVAK 373 >1XDH-A nrPDB Length = 331 Score = 359 bits (921), Expect = 1e-99, Method: Composition-based stats. Identities = 109/338 (32%), Positives = 172/338 (50%), Gaps = 12/338 (3%) Query: 67 LTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHS 126 L + + L ++ N +YG+ +G Q F I DTGSANLWVPS KC+ C Sbjct: 1 LGSSNDNIELVDFQNIMFYGDAEVGDNQQPFTFILDTGSANLWVPSVKCTT--AGCLTKH 58 Query: 127 LYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FM 184 LY+SS S +Y ++G+ ++Y SG V GF S+D VTVG +++ F EV + + Sbjct: 59 LYDSSKSRTYEKDGTKVEMNYVSGTVSGFFSKDLVTVGNLSLPYKFIEVIDTNGFEPTYT 118 Query: 185 LAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDP 244 + FDG+LG+G+ ++G V P+ + +Q ++ +F+ Y G + +GG + Sbjct: 119 ASTFDGILGLGWKDLSIGSVDPIVVELKNQNKIENALFTFYLPVHDK-HTGFLTIGGIEE 177 Query: 245 QHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIM 304 + Y+G Y ++ WQIT+ VG+ L E +VD+G+S I+ PT L ++ Sbjct: 178 RFYEGPLTYEKLNHDLYWQITLDA-HVGNIML---EKANCIVDSGTSAITVPTDFLNKML 233 Query: 305 QALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHA 364 Q L + + V LP F YTL Y+ + LC L + Sbjct: 234 QNLDVIKVPFLPFYVTLCNNSKLPTFEFTSENGKYTLEPEYYLQHIEDVGPGLCMLNIIG 293 Query: 365 MDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 +D P PT ++LG F+RK++T FD N+ +G ALA+ Sbjct: 294 LDFPVPT---FILGDPFMRKYFTVFDYDNHSVGIALAK 328 >5I70-B nrPDB Length = 328 Score = 352 bits (902), Expect = 2e-97, Method: Composition-based stats. Identities = 108/337 (32%), Positives = 171/337 (50%), Gaps = 14/337 (4%) Query: 69 NLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLY 128 + + L + N +YGE IGT Q F IFDTGSANLWVPS C + C LY Sbjct: 1 SENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDS--IGCSTKHLY 58 Query: 129 ESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP--FMLA 186 ++S S SY ++G+ I YGSG V+G+ S+D +++G +++ F EVT+ + + + Sbjct: 59 DASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGS 118 Query: 187 KFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQH 246 +FDG+LG+G+ ++G + PV + Q + +F+ Y G + +GG + Sbjct: 119 EFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDK-HVGYLTIGGIESDF 177 Query: 247 YQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQA 306 Y+G Y ++ WQI + + G + + VVD+G+S I+APTS L + Sbjct: 178 YEGPLTYEKLNHDLYWQIDLD-IHFGKYVM---QKANAVVDSGTSTITAPTSFLNKFFRD 233 Query: 307 LGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAM 365 + K + YV C LP + F YTL Y+ + LC L + + Sbjct: 234 MNVIKVPFLPLYVTTCDN-DDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPV 292 Query: 366 DIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 DI T ++LG F+RK++T FD +GFA+A+ Sbjct: 293 DIDDNT---FILGDPFMRKYFTVFDYEKESVGFAVAK 326 >3QVI-A nrPDB Length = 451 Score = 338 bits (868), Expect = 2e-93, Method: Composition-based stats. Identities = 95/348 (27%), Positives = 172/348 (49%), Gaps = 14/348 (4%) Query: 58 WGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSR 117 TK+ L + V L + N +GE +G Q F +F T S+N+WVPS KC+ Sbjct: 113 NKGLTKKSYLGSEFDNVELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTS 172 Query: 118 LYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTE 177 +C + Y+SS S +Y ++ + + +G + G S+D VT+G ++V F E+TE Sbjct: 173 --ESCESKNHYDSSKSKTYEKDDTPVKLTSKAGTISGIFSKDLVTIGKLSVPYKFIEMTE 230 Query: 178 LPLIP--FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGG 235 + + + DGV G+G+ ++G + P + +Q +++ V+S+Y + G Sbjct: 231 IVGFEPFYSESDVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLP-PENKNKG 289 Query: 236 EVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISA 295 + +GG + + + G +Y ++ WQ+ + V G+ + + V++D+ +S I+ Sbjct: 290 YLTIGGIEERFFDGPLNYEKLNHDLMWQVDLD-VHFGN---VSSKKANVILDSATSVITV 345 Query: 296 PTSSLKLIMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRR 354 PT +++ K + YV C LP + + + YTL Y+ N Sbjct: 346 PTEFFNQFVESASVFKVPFLSLYVTTCGNTK-LPTLEYRSPNKVYTLEPKQYLEPLENIF 404 Query: 355 DKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 LC L + +D+ T +VLG F+RK++T +D N+ +GFALA+ Sbjct: 405 SALCMLNIVPIDLEKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAK 449 >3FNT-A nrPDB Length = 332 Score = 330 bits (845), Expect = 9e-91, Method: Composition-based stats. Identities = 93/341 (27%), Positives = 169/341 (49%), Gaps = 14/341 (4%) Query: 65 PSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGI 124 L + V L + N +GE +G Q F +F T S+N+WVPS KC+ +C Sbjct: 1 SYLGSEFDNVELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTS--ESCES 58 Query: 125 HSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP-- 182 + Y+SS S +Y ++ + + +G + G S+D VT+G ++V F E+TE+ Sbjct: 59 KNHYDSSKSKTYEKDDTPVKLTSKAGTISGIFSKDLVTIGKLSVPYKFIEMTEIVGFEPF 118 Query: 183 FMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGS 242 + + DGV G+G+ ++G + P + +Q +++ V+S+Y + G + +GG Sbjct: 119 YSESDVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLP-PENKNKGYLTIGGI 177 Query: 243 DPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKL 302 + + + G +Y ++ WQ+ + V G+ + + V++D+ +S I+ PT Sbjct: 178 EERFFDGPLNYEKLNHDLMWQVDLD-VHFGN---VSSKKANVILDSATSVITVPTEFFNQ 233 Query: 303 IMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLA 361 +++ K + YV C LP + + + YTL Y+ N LC L Sbjct: 234 FVESASVFKVPFLSLYVTTCGNTK-LPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLN 292 Query: 362 LHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 + +D+ T +VLG F+RK++T +D N+ +GFALA+ Sbjct: 293 IVPIDLEKNT---FVLGDPFMRKYFTVYDYDNHTVGFALAK 330 >4OC6-B nrPDB Length = 243 Score = 312 bits (800), Expect = 1e-85, Method: Composition-based stats. Identities = 104/240 (43%), Positives = 153/240 (63%), Gaps = 2/240 (0%) Query: 164 GGITV-TQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVF 222 GG+ V Q FGE T+ P I F+ AKFDG+LGM +P +V V PVFD+++ Q ++ + +F Sbjct: 1 GGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIF 60 Query: 223 SVYYNRGSHL-LGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEG 281 S Y +R GGE++LGG+D ++Y+G+ Y+++++ WQ+ + V V S LC+EG Sbjct: 61 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 120 Query: 282 CAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTL 341 C +VDTG+S + P ++ + +A+GA EY++ C +V TLP I+ LGG+ Y L Sbjct: 121 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 180 Query: 342 SSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 S DY L+ LC MDIPPP+GP+W+LG FI ++YT FDR NNR+GFA A Sbjct: 181 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEA 240 >1QDM-A nrPDB Length = 478 Score = 310 bits (793), Expect = 9e-85, Method: Composition-based stats. Identities = 124/286 (43%), Positives = 171/286 (59%), Gaps = 9/286 (3%) Query: 30 ERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNL--TSPVVLTNYLNTQYYGE 87 RI LKK P R G+ E + + L + V L NY+N QY+GE Sbjct: 1 VRIALKKRPIDRNSRVATGLSG---GEEQPLLSGANPLRSEEEGDIVALKNYMNAQYFGE 57 Query: 88 IGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHY 147 IG+GTPPQ F VIFDTGS+NLWVPS KC +AC +HS Y++ SS+Y +NG I Y Sbjct: 58 IGVGTPPQKFTVIFDTGSSNLWVPSAKC-YFSIACYLHSRYKAGASSTYKKNGKPAAIQY 116 Query: 148 GSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTP 206 G+G + G+ S+DSVTVG + V Q F E T+ P I F++AKFDG+LG+GF +VG P Sbjct: 117 GTGSIAGYFSEDSVTVGDLVVKDQEFIEATKEPGITFLVAKFDGILGLGFKEISVGKAVP 176 Query: 207 VFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQIT 265 V+ ++ QG++ + VFS + NR GGE++ GG DP+HY G YV +++ WQ Sbjct: 177 VWYKMIEQGLVSDPVFSFWLNRHVDEGEGGEIIFGGMDPKHYVGEHTYVPVTQKGYWQFD 236 Query: 266 MKGVSVGS-STLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK 310 M V VG ST C GCA + D+G+S ++ PT+ + I + +GA Sbjct: 237 MGDVLVGGKSTGFCAGGCAAIADSGTSLLAGPTAIITEINEKIGAA 282 Score = 127 bits (318), Expect = 1e-29, Method: Composition-based stats. Identities = 37/103 (35%), Positives = 54/103 (52%) Query: 299 SLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLC 358 L + Q + E V+C + ++PDI F +GG+ + L +Y+L+ C Sbjct: 375 ILDYVNQLCNRLPSPMGESAVDCGSLGSMPDIEFTIGGKKFALKPEEYILKVGEGAAAQC 434 Query: 359 TLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 AMDIPPP GP+W+LG F+ ++T FD RIGFA A Sbjct: 435 ISGFTAMDIPPPRGPLWILGDVFMGPYHTVFDYGKLRIGFAKA 477 >1B5F-A nrPDB Length = 239 Score = 283 bits (725), Expect = 7e-77, Method: Composition-based stats. Identities = 114/242 (47%), Positives = 153/242 (63%), Gaps = 8/242 (3%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYES 130 ++ V LTN +T Y+GEIGIGTPPQ F VIFDTGS+ LWVPS+KC AC HS+YES Sbjct: 2 SAVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKCINSK-ACRAHSMYES 60 Query: 131 SDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFD 189 SDSS+Y ENG+ I YG+G + GF SQDSVT+G + V Q F E T+ F+ FD Sbjct: 61 SDSSTYKENGTFGAIIYGTGSITGFFSQDSVTIGDLVVKEQDFIEATDEADNVFLHRLFD 120 Query: 190 GVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRG-SHLLGGEVVLGGSDPQHYQ 248 G+LG+ F +V PV+ ++L+QG++KE FS + NR GGE+V GG DP H++ Sbjct: 121 GILGLSFQTISV----PVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELVFGGLDPNHFR 176 Query: 249 GNFHYVSISKTDSWQITMKGVSVGS-STLLCEEGCAVVVDTGSSFISAPTSSLKLIMQAL 307 G+ YV ++ WQ + V +G ST C GC D+G+S +S PT+ + I A+ Sbjct: 177 GDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHAI 236 Query: 308 GA 309 GA Sbjct: 237 GA 238 >1UH8-A nrPDB Length = 325 Score = 273 bits (699), Expect = 8e-74, Method: Composition-based stats. Identities = 93/333 (27%), Positives = 165/333 (49%), Gaps = 20/333 (6%) Query: 74 VVLTNYL-NTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGI-HSLYESS 131 V +T+Y + +YYG++ IGTP + F + FDTGS++LW+ ST C+ CG + Y+ + Sbjct: 6 VPMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLCTN----CGSRQTKYDPN 61 Query: 132 DSSSYMENGSDFTIHYGSGR-VKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDG 190 SS+Y +G ++I YG G G L++D+V +GG+ + E+ + F DG Sbjct: 62 QSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTIELAKREAASFASGPNDG 121 Query: 191 VLGMGFPAQA-VGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQG 249 +LG+GF V GV D+++SQG++ +F VY + + GGE + GG D ++G Sbjct: 122 LLGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYLGKAKNGGGGEYIFGGYDSTKFKG 181 Query: 250 NFHYVSISKTDSWQ-ITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALG 308 + V I + W IT+ +VG+ST+ ++DTG++ + P + + +A G Sbjct: 182 SLTTVPIDNSRGWWGITVDRATVGTSTVASS--FDGILDTGTTLLILPNNIAASVARAYG 239 Query: 309 AKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIP 368 A + Y ++C P + F + G ++ +S V + + + D Sbjct: 240 ASDNGDGTYTISCDTSRFKP-LVFSINGASFQVSPDSLVFE-EFQGQCIAGFGYGNWDFA 297 Query: 369 PPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 ++G TF++ Y F++ + A Sbjct: 298 -------IIGDTFLKNNYVVFNQGVPEVQIAPV 323 >2QZW-A nrPDB Length = 341 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 89/347 (25%), Positives = 154/347 (44%), Gaps = 37/347 (10%) Query: 73 PVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVP--STKCSRLYLA-----CGIH 125 PV L N + Y +I IG+ Q F VI DTGS++LWVP S C + C Sbjct: 4 PVTLNNE-HVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGK 62 Query: 126 SLYESSDSSSYMENGSDFTIHYGSGRVK-GFLSQDSVTVGGITVT-QTFGEVTELPLIPF 183 +Y S++ G+ F I YG G G L +D+V GG ++T Q F ++T+ + Sbjct: 63 GIYTPKSSTTSQNLGTPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQ- 121 Query: 184 MLAKFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGS 242 G+LG+G+ +A G V + +QGV+ + +S+Y N + G+++ GG Sbjct: 122 ------GILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNS-PNAATGQIIFGGV 174 Query: 243 DPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKL 302 D Y G+ V ++ +IT+ + + V++D+G++ + Sbjct: 175 DKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNI--NGNIDVLLDSGTTITYLQQDVAQD 232 Query: 303 IMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDK-- 356 I+ A A+ K + YV +C T+ D +FD ++ ++++ + Sbjct: 233 IIDAFQAELKSDGQGHTFYVTDCQTSGTV-DFNFD-NNAKISVPASEFTAPLSYANGQPY 290 Query: 357 -LCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C L L D +LG F+R Y +D +++I A + Sbjct: 291 PKCQLLLGISDAN-------ILGDNFLRSAYLVYDLDDDKISLAQVK 330 >3LIZ-A nrPDB Length = 334 Score = 266 bits (681), Expect = 8e-72, Method: Composition-based stats. Identities = 87/328 (26%), Positives = 155/328 (47%), Gaps = 18/328 (5%) Query: 79 YLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYME 138 ++NTQY G IG Q F +FD+ S N+ V S +C C YE Y+ Sbjct: 16 FINTQYAGITKIGN--QNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLK-PKYIS 72 Query: 139 NGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPA 198 +G+ + +G G +DS+T+ +T +Q + + + D V+G+ P Sbjct: 73 DGNVQVKFFDTGSAVGRGIEDSLTISQLTTSQQDIVLADELSQEVCILSADVVVGIAAPG 132 Query: 199 -QAVGGVTPVFDHILSQGVLKEEVFSVYYNR-GSHLLGGEVVLGGSDPQHYQGNFHYVSI 256 V ++ + + ++ VFS+++ R GE++ GGSD ++ G F YV + Sbjct: 133 CPNALKGKTVLENFVEENLIA-PVFSIHHARFQDGEHFGEIIFGGSDWKYVDGEFTYVPL 191 Query: 257 SKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEE 316 DSW+ + GV +G +T+ G ++DT + I P + + I +A+G ++ Sbjct: 192 VGDDSWKFRLDGVKIGDTTVA-PAGTQAIIDTSKAIIVGPKAYVNPINEAIGCVVEKTTT 250 Query: 317 YVV---NCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGP 373 + +CS++P+LPD++F + GR + +SS Y+ Q N LC P Sbjct: 251 RRICKLDCSKIPSLPDVTFVINGRNFNISSQYYIQQNGN----LCYSGFQ----PCGHSD 302 Query: 374 VWVLGATFIRKFYTEFDRHNNRIGFALA 401 + +G F+ +Y+EF+ N +GF + Sbjct: 303 HFFIGDFFVDHYYSEFNWENKTMGFGRS 330 >2ASI-A nrPDB Length = 361 Score = 265 bits (677), Expect = 3e-71, Method: Composition-based stats. Identities = 92/348 (26%), Positives = 151/348 (43%), Gaps = 33/348 (9%) Query: 78 NYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYM 137 ++ +Y + IGTP Q F ++FDTGS++ WVP C++ C ++ S SS++ Sbjct: 14 DFDLEEYAIPVSIGTPGQDFLLLFDTGSSDTWVPHKGCTKSE-GCVGSRFFDPSASSTFK 72 Query: 138 ENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTE------LPLIPFMLAKFDGV 191 + I YG+G G +DS+ +G ITVT+ + P DG+ Sbjct: 73 ATNYNLNITYGTGGANGLYFEDSIAIGDITVTKQILAYVDNVRGPTAEQSPNADIFLDGL 132 Query: 192 LGMGFPAQAV------GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQ 245 G +P V ++ QG++ +FSVY N S GEVV GG + Sbjct: 133 FGAAYPDNTAMEAEYGSTYNTVHVNLYKQGLISSPLFSVYMNTNSGT--GEVVFGGVNNT 190 Query: 246 HYQGNFHYVSISKTDS----WQITMKGVSV-GSSTLLCEEGCAVVVDTGSSFISAPTSSL 300 G+ Y + W + G++V GS+ + A +DTG++F P+S+ Sbjct: 191 LLGGDIAYTDVMSRYGGYYFWDAPVTGITVDGSAAVRFSRPQAFTIDTGTNFFIMPSSAA 250 Query: 301 KLI-MQALGAKEKRIEEYVVNCSQV----PTLPDISFDLGGRAYTLS---STDYVLQYPN 352 I AL + + +VV C+ T+ + G + T+ +L + Sbjct: 251 SKIVKAALPDATETQQGWVVPCASYQNSKSTISIVMQKSGSSSDTIEISVPVSKMLLPVD 310 Query: 353 RRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFAL 400 + ++ C I P G +++G F+R F +D NNRIGFA Sbjct: 311 QSNETCMFI-----ILPDGGNQYIVGNLFLRFFVNVYDFGNNRIGFAP 353 >3PVK-A nrPDB Length = 342 Score = 264 bits (674), Expect = 6e-71, Method: Composition-based stats. Identities = 85/349 (24%), Positives = 144/349 (41%), Gaps = 38/349 (10%) Query: 72 SPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTK--CSRLYLA-----CGI 124 PV L N T Y +I +G+ Q VI DTGS++LWVP C Y C Sbjct: 3 VPVTLHNEQVT-YAADITVGSNNQKLNVIVDTGSSDLWVPDVNVDCQVTYSDQTADFCKQ 61 Query: 125 HSLYESSDSSSYMENGSDFTIHYGSGRVK-GFLSQDSVTVGGITV-TQTFGEVTELPLIP 182 Y+ S SS+ + + F I YG G G L +D+V GG+++ Q +V + Sbjct: 62 KGTYDPSGSSASQDLNTPFKIGYGDGSSSQGTLYKDTVGFGGVSIKNQVLADVDSTSIDQ 121 Query: 183 FMLAKFDGVLGMGFPAQAVGG-VTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGG 241 G+LG+G+ GG V + QGV+ + +S+Y N G+++ GG Sbjct: 122 -------GILGVGYKTNEAGGSYDNVPVTLKKQGVIAKNAYSLYLNS-PDAATGQIIFGG 173 Query: 242 SDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLK 301 D Y G+ + ++ +I++ V V T+ + V++D+G++ Sbjct: 174 VDNAKYSGSLIALPVTSDRELRISLGSVEVSGKTIN-TDNVDVLLDSGTTITYLQQDLAD 232 Query: 302 LIMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLG-GRAYTLSSTDYVLQYPNRRD- 355 I++A K + Y V+C+ D+ F+ ++ ++++ Sbjct: 233 QIIKAFNGKLTQDSNGNSFYEVDCNLSG---DVVFNFSKNAKISVPASEFAASLQGDDGQ 289 Query: 356 --KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C L D +LG F+R Y +D +N I A + Sbjct: 290 PYDKCQLLFDVNDAN-------ILGDNFLRSAYIVYDLDDNEISLAQVK 331 >2H6T-A nrPDB Length = 340 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 85/348 (24%), Positives = 152/348 (43%), Gaps = 36/348 (10%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA------CGI 124 T PV L N Y +I +G+ Q V+ DTGS++LWVP ++ S C Sbjct: 2 TVPVKLINE-QVSYASDITVGSNKQKLTVVIDTGSSDLWVPDSQVSCQAGQGQDPNFCKN 60 Query: 125 HSLYESSDSSSYMENGSDFTIHYGSGRVK-GFLSQDSVTVGGITVT-QTFGEVTELPLIP 182 Y S SSS S F+I YG G G +D++ GGI++T Q F +VT + Sbjct: 61 EGTYSPSSSSSSQNLNSPFSIEYGDGTTSQGTWYKDTIGFGGISITKQQFADVTSTSVDQ 120 Query: 183 FMLAKFDGVLGMGFPA-QAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGG 241 G+LG+G+ +A G V + +QG++ + +S+Y N G+++ GG Sbjct: 121 -------GILGIGYKTHEAEGNYDNVPVTLKNQGIISKNAYSLYLNS-RQATSGQIIFGG 172 Query: 242 SDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLK 301 D Y G + ++ + +I + V V ++ + V++D+G++ Sbjct: 173 VDNAKYSGTLIALPVTSDNELRIHLNTVKVAGQSINAD--VDVLLDSGTTITYLQQGVAD 230 Query: 302 LIMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 ++ A +E Y+V+C+ ++ D +FD + ++ ++++ ++ Sbjct: 231 QVISAFNGQETYDANGNLFYLVDCNLSGSV-DFAFDKNAK-ISVPASEFTAPLYTEDGQV 288 Query: 358 ---CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C L D +LG F+R Y +D +N I A + Sbjct: 289 YDQCQLLFGTSDYN-------ILGDNFLRSAYIVYDLDDNEISLAQVK 329 >1J71-A nrPDB Length = 334 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 81/345 (23%), Positives = 147/345 (42%), Gaps = 33/345 (9%) Query: 70 LTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPST--KCSRLYLA-----C 122 P L N Y +I +G+ Q V+ DTGS++LWV T +C Y C Sbjct: 1 SDVPTTLINEG-PSYAADIVVGSNQQKQTVVIDTGSSDLWVVDTDAECQVTYSGQTNNFC 59 Query: 123 GIHSLYESSDSSSYMENGSDFTIHYGS-GRVKGFLSQDSVTVGGITV-TQTFGEVTELPL 180 ++ S SSS DF+I YG +G +D+V GGI++ Q F +VT + Sbjct: 60 KQEGTFDPSSSSSAQNLNQDFSIEYGDLTSSQGSFYKDTVGFGGISIKNQQFADVTTTSV 119 Query: 181 IPFMLAKFDGVLGMGFPAQAVGG--VTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVV 238 G++G+GF A G V + QG++ + +S+Y N G+++ Sbjct: 120 DQ-------GIMGIGFTADEAGYNLYDNVPVTLKKQGIINKNAYSLYLNS-EDASTGKII 171 Query: 239 LGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTS 298 GG D Y G + ++ + ++ + ++ +++ VV+D+G++ S Sbjct: 172 FGGVDNAKYTGTLTALPVTSSVELRVHLGSINFDGTSV--STNADVVLDSGTTITYFSQS 229 Query: 299 SLKLIMQALGAK-EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 + + +GA + R E Y + + +FD G T+ ++ +L+ + + Sbjct: 230 TADKFARIVGATWDSRNEIYRLPSCDLSGDAVFNFDQ-GVKITVPLSELILK--DSDSSI 286 Query: 358 CTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C + D +LG F+R+ Y +D + I A + Sbjct: 287 CYFGISRNDAN-------ILGDNFLRRAYIVYDLDDKTISLAQVK 324 >1MPP-A nrPDB Length = 361 Score = 253 bits (647), Expect = 8e-68, Method: Composition-based stats. Identities = 91/350 (26%), Positives = 144/350 (41%), Gaps = 33/350 (9%) Query: 76 LTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSS 135 L ++ +Y + IGTP Q F ++FDTGS++ WVP C C ++ S SS+ Sbjct: 12 LYDFDLEEYAIPVSIGTPGQDFYLLFDTGSSDTWVPHKGCDNSE-GCVGKRFFDPSSSST 70 Query: 136 YMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQT-FGEVTELPL-----IPFMLAKFD 189 + E + I YG+G G +DS+TVGG TV Q V + P D Sbjct: 71 FKETDYNLNITYGTGGANGIYFRDSITVGGATVKQQTLAYVDNVSGPTAEQSPDSELFLD 130 Query: 190 GVLGMGFPAQAV------GGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSD 243 G+ G +P V ++ QG++ VFSVY N G + Sbjct: 131 GIFGAAYPDNTAMEAEYGDTYNTVHVNLYKQGLISSPVFSVYMNTNDGGGQVVFG--GVN 188 Query: 244 PQHYQGNFHYVSISKTDS----WQITMKGVSVGSSTLLCEEGCAV-VVDTGSSFISAPTS 298 G+ Y + K+ W + GV + S + +G +DTG++F AP+S Sbjct: 189 NTLLGGDIQYTDVLKSRGGYFFWDAPVTGVKIDGSDAVSFDGAQAFTIDTGTNFFIAPSS 248 Query: 299 SLKL-IMQALGAKEKRIEEYVVNCSQVP----TLPDISFDLGGRAYTLS---STDYVLQY 350 + + AL + + Y V CS+ T + G + T+ +L Sbjct: 249 FAEKVVKAALPDATESQQGYTVPCSKYQDSKTTFSLVLQKSGSSSDTIDVSVPISKMLLP 308 Query: 351 PNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFAL 400 ++ + C + P G +++G F+R F +D NRIGFA Sbjct: 309 VDKSGETCMFI-----VLPDGGNQFIVGNLFLRFFVNVYDFGKNRIGFAP 353 >4Y9W-A nrPDB Length = 334 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 79/331 (23%), Positives = 137/331 (41%), Gaps = 30/331 (9%) Query: 83 QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSD 142 Y + +G+ Q +V+ DTGS++ WV + S C + ++ S+S+ GS Sbjct: 13 SYGIRVSVGSNKQEQQVVLDTGSSDFWVVDSSASCQKGNCKQYGTFDPHSSTSFKSLGSS 72 Query: 143 FTIHYGSGRVK-GFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQA 200 F+I YG G QD++ +GG ++T Q F +VT + G+LG+G Sbjct: 73 FSIGYGDKSSSIGTWGQDTIYLGGTSITNQRFADVTSTSV-------NQGILGVG--RVE 123 Query: 201 VGGVTPVFDH----ILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSI 256 P +D+ + QG +K +S+Y N G ++ GG D Y G + Sbjct: 124 TESANPPYDNVPITLKKQGKIKTNAYSLYLNS-PGAATGTIIFGGVDNAKYSGKLIEEPL 182 Query: 257 SKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIE- 315 + +K ++ G VVVD+G++ P S + + +GA + + Sbjct: 183 VSDRYLAVNLKSLNYNGDN--SNAGFGVVVDSGTTISYLPDSIVDDLANKVGAYLEPVGL 240 Query: 316 ---EYVVNCSQVPT-LPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPT 371 Y ++C+ P +FD G T+ +++VLQ C L + D Sbjct: 241 GNELYFIDCNANPQGSASFTFD-NGAKITVPLSEFVLQ---STANACVWGLQSSD---RQ 293 Query: 372 GPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 +LG F+R Y F+ + A + Sbjct: 294 NVPPILGDNFLRHAYVVFNLDKETVSLAQVK 324 >3TPL-A nrPDB Length = 433 Score = 247 bits (631), Expect = 6e-66, Method: Composition-based stats. Identities = 86/351 (24%), Positives = 146/351 (41%), Gaps = 40/351 (11%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDF 143 YY E+ +G+PPQT ++ DTGS+N V + L H Y+ SS+Y + Sbjct: 54 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 107 Query: 144 TIHYGSGRVKGFLSQDSVTVG---GITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQA 200 + Y G G L D V++ +TV +TE + ++G+LG+ + A Sbjct: 108 YVPYTQGAWAGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 167 Query: 201 --VGGVTPVFDHILSQGVLKEEVFSVYYNRGS---------HLLGGEVVLGGSDPQHYQG 249 + P FD ++ Q + +FS+ +GG +++GG D Y G Sbjct: 168 RPDDSLEPFFDSLVKQTHVP-NLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTG 226 Query: 250 NFHYVSISKTDSWQITMKGVSVGSSTLL--CEEGC--AVVVDTGSSFISAPTSSLKLIMQ 305 + Y I + +++ + V + L C+E +VD+G++ + P + ++ Sbjct: 227 SLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVK 286 Query: 306 ALGAK---EKRIEEYVVN----CSQVPT-----LPDISFDLGGRAYTLSSTDYVL--QYP 351 ++ A EK + + + C Q T P IS L G S +L QY Sbjct: 287 SIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYL 346 Query: 352 NRRDKLCTLALHAMDIP-PPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 + + T + V+GA + FY FDR RIGFA++ Sbjct: 347 RPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVS 397 >3FV3-A nrPDB Length = 339 Score = 247 bits (631), Expect = 7e-66, Method: Composition-based stats. Identities = 83/338 (24%), Positives = 149/338 (44%), Gaps = 39/338 (11%) Query: 83 QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLY-LACGIHSLYESSDSSSYMENGS 141 Y ++ +G+ Q VI DTGS++ WV + + C + S SSSY G+ Sbjct: 13 SYASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKGVDCKSSGTFTPSSSSSYKNLGA 72 Query: 142 DFTIHYGSGRVK-GFLSQDSVTVGGITVT-QTFGEVTELPLIPFMLAKFDGVLGMGFPAQ 199 FTI YG G G +D+VT+ G+++T Q +VT+ + G+LG+G+ + Sbjct: 73 AFTIRYGDGSTSQGTWGKDTVTINGVSITGQQIADVTQTSVDQ-------GILGIGYTSN 125 Query: 200 ------AVGGVTPVFDH----ILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQG 249 + TP +D+ + QG ++ +S+Y N S G ++ GG D Y G Sbjct: 126 EAVYDTSGRQTTPNYDNVPVTLKKQGKIRTNAYSLYLNSPS-AETGTIIFGGVDNAKYSG 184 Query: 250 NFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGA 309 ++ + + I++ V++ S+ +G ++D+G++ P+ + GA Sbjct: 185 KLVAEQVTSSQALTISLASVNLKGSSFSFGDG--ALLDSGTTLTYFPSDFAAQLADKAGA 242 Query: 310 KEKRIE----EYVVNCSQVPTLPDISFDLG-GRAYTLSSTDYVLQYPNRRDKLCTLALHA 364 + ++ Y ++C+ T F+ G G T+ +T+YV Q D C + Sbjct: 243 RLVQVARDQYLYFIDCNT-DTSGTTVFNFGNGAKITVPNTEYVYQ---NGDGTCLWGIQP 298 Query: 365 MDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 D +LG F+R Y ++ N I A + Sbjct: 299 SDDT-------ILGDNFLRHAYLLYNLDANTISIAQVK 329 >2QZX-A nrPDB Length = 342 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 82/348 (23%), Positives = 150/348 (43%), Gaps = 40/348 (11%) Query: 74 VVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTK--CSRLYLA-----CGIHS 126 V L N T Y +I +G+ Q VI DTGS++LW+P + C + C Sbjct: 5 VTLHNEAIT-YTADITVGSDNQKLNVIVDTGSSDLWIPDSNVICIPKWRGDKGDFCKSAG 63 Query: 127 LYESSDSSSYMENGSDFTIHYGSGR-VKGFLSQDSVTVGGITVT-QTFGEVTELPLIPFM 184 Y + S + + F I YG G KG L +D+V +GG++V Q F V + Sbjct: 64 SYSPASSRTSQNLNTRFDIKYGDGSYAKGKLYKDTVGIGGVSVRDQLFANV-------WS 116 Query: 185 LAKFDGVLGMGFPAQAVGG--VTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGS 242 + G+LG+GF + + + +QG++ + +S+Y N G+++ GG Sbjct: 117 TSARKGILGIGFQSGEATEFDYDNLPISLRNQGIIGKAAYSLYLNSAE-ASTGQIIFGGI 175 Query: 243 DPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKL 302 D Y G+ + I+ + ++ V+V + + V++D+G++ S ++ Sbjct: 176 DKAKYSGSLVDLPITSEKKLTVGLRSVNVRGRNV--DANTNVLLDSGTTISYFTRSIVRN 233 Query: 303 IMQALGAKEKRIEE----YVVNCSQVPTLPDISFDLGGR-AYTLSSTDYVLQYPNRRDK- 356 I+ A+GA+ K YV +C T I F G ++ ++++ Q K Sbjct: 234 ILYAIGAQMKFDSAGNKVYVADCKTSGT---IDFQFGNNLKISVPVSEFLFQTYYTSGKP 290 Query: 357 --LCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 C + + + +LG F+R Y ++ + +I A + Sbjct: 291 FPKCEVRIRESEDN-------ILGDNFLRSAYVVYNLDDKKISMAPVK 331 >3ZKX-A nrPDB Length = 386 Score = 240 bits (612), Expect = 9e-64, Method: Composition-based stats. Identities = 95/347 (27%), Positives = 152/347 (43%), Gaps = 40/347 (11%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDF 143 YY E+ IGTPPQ +++ DTGS+N V T S I + +++ SS+Y G D Sbjct: 18 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 71 Query: 144 TIHYGSGRVKGFLSQDSVTVG-GITVTQTFGEVTELPLIPFML--AKFDGVLGMGFPAQA 200 T+ Y G GF+ +D VT+ G + T F L K++G+LG+ + A Sbjct: 72 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLA 131 Query: 201 --VGGVTPVFDHILSQGVLKEEVFSVYYN------RGSHLLGGEVVLGGSDPQHYQGNFH 252 + FD +++Q + VFS+ GS GG +VLGG +P Y+G+ Sbjct: 132 KPSSSLETFFDSLVTQANIP-NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIW 190 Query: 253 YVSISKTDSWQITMKGVSVGSSTLL--CEEGCA--VVVDTGSSFISAPTSSLKLIMQALG 308 Y I + +QI + + +G +L C E A +VD+G++ + P +++A+ Sbjct: 191 YTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVA 250 Query: 309 AK-------EKRIEEYVVNCSQV-----PTLPDISFDL----GGRAYTLSSTDYVLQYPN 352 + + C P IS L R++ ++ + P Sbjct: 251 RASLIPAFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPM 310 Query: 353 RRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFA 399 L + I P T + V+GAT + FY FDR R+GFA Sbjct: 311 MGAGL-NYECYRFGISPSTNAL-VIGATVMEGFYVIFDRAQKRVGFA 355 >4B1C-A nrPDB Length = 375 Score = 234 bits (596), Expect = 7e-62, Method: Composition-based stats. Identities = 84/342 (24%), Positives = 144/342 (42%), Gaps = 36/342 (10%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDF 143 YY E+ +G+PPQT ++ DTGS+N V + L H Y+ SS+Y + Sbjct: 20 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFL------HRYYQRQLSSTYRDLRKGV 73 Query: 144 TIHYGSGRVKGFLSQDSVTVG---GITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQA 200 + Y G+ +G L D V++ +TV +TE + ++G+LG+ + A Sbjct: 74 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA 133 Query: 201 --VGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISK 258 + P FD ++ Q + +FS+ G ++ G D Y G+ Y I + Sbjct: 134 RPDDSLEPFFDSLVKQTHVP-NLFSLQLCGGGSMIIGG-----IDHSLYTGSLWYTPIRR 187 Query: 259 TDSWQITMKGVSVGSSTLL--CEEGC--AVVVDTGSSFISAPTSSLKLIMQALGAK---E 311 +++ + V + L C+E +VD+G++ + P + ++++ A E Sbjct: 188 EWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTE 247 Query: 312 KRIEEYVVN----CSQVPT-----LPDISFDLGGRAYTLSSTDYVL--QYPNRRDKLCTL 360 K + + + C Q T P IS L G S +L QY + + T Sbjct: 248 KFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATS 307 Query: 361 ALHAMDIP-PPTGPVWVLGATFIRKFYTEFDRHNNRIGFALA 401 + V+GA + FY FDR RIGFA++ Sbjct: 308 QDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVS 349 >1IBQ-A nrPDB Length = 325 Score = 231 bits (588), Expect = 6e-61, Method: Composition-based stats. Identities = 75/326 (23%), Positives = 123/326 (37%), Gaps = 23/326 (7%) Query: 81 NTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENG 140 + +Y + +G T + FDTGSA+LWV S + H LY S S++ + G Sbjct: 13 DEEYLTPVTVG--KSTLHLDFDTGSADLWVFSDELPSSEQ--TGHDLYTPSSSATKLS-G 67 Query: 141 SDFTIHYGSGR-VKGFLSQDSVTVGGITVTQTFGEVTELPLIPF-MLAKFDGVLGMGFPA 198 + I YG G G + +D+VTVGG+T + E F DG+LG+ F + Sbjct: 68 YSWDISYGDGSSASGDVYRDTVTVGGVTTNKQAVEAASKISSEFVQDTANDGLLGLAFSS 127 Query: 199 QAVGGV---TPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVS 255 T FD + SQ L +F+V H G G D Y G+ Y Sbjct: 128 INTVQPKAQTTFFDTVKSQ--LDSPLFAVQL---KHDAPGVYDFGYIDDSKYTGSITYTD 182 Query: 256 ISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRI- 314 + + G + + DTG++ I + + + ++ Sbjct: 183 ADSSQGYWGFSTDGYSIGDGSSSSSGFSAIADTGTTLILLDDEIVSAYYEQVSGAQESYE 242 Query: 315 -EEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGP 373 YV +CS LPD + +G + + C + + Sbjct: 243 AGGYVFSCST--DLPDFTVVIGDYKAVVPGKYINYAPVSTGSSTCYGGIQSN----SGLG 296 Query: 374 VWVLGATFIRKFYTEFDRHNNRIGFA 399 + +LG F++ Y F+ ++GFA Sbjct: 297 LSILGDVFLKSQYVVFNSEGPKLGFA 322 >3O9L-A nrPDB Length = 166 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 118/165 (71%), Positives = 143/165 (86%) Query: 66 SLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIH 125 +L N TS V+LTNY++TQYYGEIGIGTPPQTFKV+FDTGS+N+WVPS+KCSRLY AC H Sbjct: 2 TLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYH 61 Query: 126 SLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFML 185 L+++SDSSSY NG++ T+ Y +G V GFLSQD +TVGGITVTQ FGEVTE+P +PFML Sbjct: 62 KLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFML 121 Query: 186 AKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGS 230 A+FDGV+GMGF QA+G VTP+FD+I+SQGVLKE+VFS YYNR S Sbjct: 122 AEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDS 166 >1PPK-E nrPDB Length = 323 Score = 225 bits (573), Expect = 3e-59, Method: Composition-based stats. Identities = 81/328 (24%), Positives = 132/328 (40%), Gaps = 28/328 (8%) Query: 81 NTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENG 140 + +Y + IG T + FDTGSA+LWV ST+ + HS+Y S + + G Sbjct: 14 DEEYITPVTIG--GTTLNLNFDTGSADLWVFSTELPASQQSG--HSVYNPSATGKELS-G 68 Query: 141 SDFTIHYGSGR-VKGFLSQDSVTVGGITVTQTFGEVTELPLIPF-MLAKFDGVLGMGFPA 198 ++I YG G G + DSVTVGG+T + + F DG+LG+ F + Sbjct: 69 YTWSISYGDGSSASGNVFTDSVTVGGVTAHGQAVQAAQQISAQFQQDTNNDGLLGLAFSS 128 Query: 199 QAVGGV---TPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVS 255 T FD + S L + +F+V H G G D Y G+ Y Sbjct: 129 INTVQPQSQTTFFDTVKSS--LAQPLFAVAL---KHQQPGVYDFGFIDSSKYTGSLTYTG 183 Query: 256 I-SKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK--EK 312 + + W + + GS + +G + + DTG++ + S + + + Sbjct: 184 VDNSQGFWSFNVDSYTAGSQSG---DGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDS 240 Query: 313 RIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTG 372 YV +CS LPD S + G T+ + + P+ C + + Sbjct: 241 NAGGYVFDCST--NLPDFSVSISGYTATVPGS-LINYGPSGDGSTCLGGIQSN----SGI 293 Query: 373 PVWVLGATFIRKFYTEFDRHNNRIGFAL 400 + G F++ Y FD ++GFA Sbjct: 294 GFSIFGDIFLKSQYVVFDSDGPQLGFAP 321 >5HCT-A nrPDB Length = 419 Score = 222 bits (567), Expect = 2e-58, Method: Composition-based stats. Identities = 78/348 (22%), Positives = 138/348 (39%), Gaps = 27/348 (7%) Query: 62 TKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLA 121 +R + + T+P+ + L+ Y + IGTP QT + FDTGS++LWV S++ + + Sbjct: 87 AERSTGSATTTPI---DSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVD 143 Query: 122 CGIHSLYESSDSSSYM--ENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELP 179 ++Y S S++ + + G + D+V+VGG+TVT E + Sbjct: 144 G--QTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKV 201 Query: 180 LIPFML-AKFDGVLGMGFPAQAVGGVT---PVFDHILSQGVLKEEVFSVYYNRGSHLLGG 235 F + DG+LG+ F T FD+ + L VF+ G Sbjct: 202 SSSFTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKAS--LDSPVFTADLGYH---APG 256 Query: 236 EVVLGGSDPQHYQGNFHYVSI-SKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFIS 294 G D Y G+ Y ++ +K W+ T G +VGS T + DTG++ + Sbjct: 257 TYNFGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTS-IDGIADTGTTLLY 315 Query: 295 APTSSLKLIMQALGAKE--KRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPN 352 P + + + + + YV CS TLP +F +G + + Sbjct: 316 LPATVVSAYWAQVSGAKSSSSVGGYVFPCS--ATLPSFTFGVGSARIVIPGDYIDFGPIS 373 Query: 353 RRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFD-RHNNRIGFA 399 C + + + + G ++ + F+ +GFA Sbjct: 374 TGSSSCFGGIQS----SAGIGINIFGDVALKAAFVVFNGATTPTLGFA 417 >3OAD-B nrPDB Length = 176 Score = 218 bits (555), Expect = 4e-57, Method: Composition-based stats. Identities = 123/171 (71%), Positives = 144/171 (84%), Gaps = 1/171 (0%) Query: 232 LLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSS 291 LGG++VLGGSDPQHY+GNFHY+++ KT WQI MKGVSVGSSTLLCE+GC +VDTG+S Sbjct: 1 SLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGAS 60 Query: 292 FISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYP 351 +IS TSS++ +M+ALGAK KR+ +YVV C++ PTLPDISF LGG+ YTL+S DYV Q Sbjct: 61 YISGSTSSIEKLMEALGAK-KRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQES 119 Query: 352 NRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR 402 KLCTLA+HAMDIPPPTGP W LGATFIRKFYTEFDR NNRIGFALAR Sbjct: 120 YSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 170 >3EMY-A nrPDB Length = 329 Score = 218 bits (555), Expect = 4e-57, Method: Composition-based stats. Identities = 75/339 (22%), Positives = 131/339 (38%), Gaps = 23/339 (6%) Query: 71 TSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYES 130 ++P ++ +++Y + IGTP Q + FDTGS++LWV S++ + H++Y Sbjct: 4 SAPNHPSDSADSEYITSVSIGTPAQVLPLDFDTGSSDLWVFSSETPKSSA--TGHAIYTP 61 Query: 131 --SDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAK 187 S +S + S + G + D VT+GG +V TQ T + Sbjct: 62 SKSSTSKKVSGASWSISYGDGSSSSGDVYTDKVTIGGFSVNTQGVESATRVSTEFVQDTV 121 Query: 188 FDGVLGMGFPAQAVGGVTPV---FDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDP 244 G++G+ F + P F + S L E +F+ G + G G D Sbjct: 122 ISGLVGLAFDSGNQVRPHPQKTWFSNAASS--LAEPLFTADLRHGQN---GSYNFGYIDT 176 Query: 245 QHYQGNFHYVSI-SKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLI 303 +G Y + + W+ T G SVG L + DTG++ + + + Sbjct: 177 SVAKGPVAYTPVDNSQGFWEFTASGYSVGGGKLN-RNSIDGIADTGTTLLLLDDNVVDAY 235 Query: 304 MQALGAK--EKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLA 361 + + + + E V +C + LP SF +G T+ L C Sbjct: 236 YANVQSAQYDNQQEGVVFDCDE--DLPSFSFGVGSSTITIPGDLLNLTPLEEGSSTCFGG 293 Query: 362 LHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFAL 400 L + + + G ++ FD N R+G+A Sbjct: 294 LQS----SSGIGINIFGDVALKAALVVFDLGNERLGWAQ 328 >1IZE-A nrPDB Length = 323 Score = 217 bits (554), Expect = 5e-57, Method: Composition-based stats. Identities = 80/328 (24%), Positives = 130/328 (39%), Gaps = 30/328 (9%) Query: 81 NTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENG 140 + +Y ++ +G T + FDTGSA+LWV S++ + H Y S+ + +G Sbjct: 14 DEEYITQVTVGD--DTLGLDFDTGSADLWVFSSQTPSSERSG--HDYYTPGSSAQKI-DG 68 Query: 141 SDFTIHYGSGR-VKGFLSQDSVTVGGITVTQTFGEVTELPLIPFM-LAKFDGVLGMGFPA 198 + ++I YG G G + +D VTVGG++ E E F DG+LG+ F + Sbjct: 69 ATWSISYGDGSSASGDVYKDKVTVGGVSYDSQAVESAEKVSSEFTQDTANDGLLGLAFSS 128 Query: 199 QAVGGVTP---VFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVS 255 TP FD++ S L E +F+V H G G +D Y G+ Y Sbjct: 129 INTVQPTPQKTFFDNVKSS--LSEPIFAVAL---KHNAPGVYDFGYTDSSKYTGSITYTD 183 Query: 256 I-SKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAK--EK 312 + + W T G S + + + DTG++ + S + + + + Sbjct: 184 VDNSQGFWGFTADGYS--IGSDSSSDSITGIADTGTTLLLLDDSIVDAYYEQVNGASYDS 241 Query: 313 RIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTG 372 YV S +LPD S +G T+ I +G Sbjct: 242 SQGGYVFPSS--ASLPDFSVTIGDYTATVPGEYISFADVGNGQTF-------GGIQSNSG 292 Query: 373 PVW-VLGATFIRKFYTEFDRHNNRIGFA 399 + + G F++ Y FD R+GFA Sbjct: 293 IGFSIFGDVFLKSQYVVFDASGPRLGFA 320 >3PI0-A nrPDB Length = 330 Score = 211 bits (538), Expect = 4e-55, Method: Composition-based stats. Identities = 77/345 (22%), Positives = 136/345 (39%), Gaps = 27/345 (7%) Query: 65 PSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGI 124 + + T+P+ + L+ Y + IGTP QT + FDTGS++LWV S++ + + Sbjct: 1 STGSATTTPI---DSLDDAYITPVQIGTPAQTLNLDFDTGSSDLWVFSSETTASEVDG-- 55 Query: 125 HSLYESSDSSSYM--ENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIP 182 ++Y S S++ + + G + D+V+VGG+TVT E + Sbjct: 56 QTIYTPSKSTTAKLLSGATWSISYGDGSSSSGDVYTDTVSVGGLTVTGQAVESAKKVSSS 115 Query: 183 FML-AKFDGVLGMGFPAQAVGGVT---PVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVV 238 F + DG+LG+ F T FD+ + L VF+ G Sbjct: 116 FTEDSTIDGLLGLAFSTLNTVSPTQQKTFFDNAKAS--LDSPVFTADLGYH---APGTYN 170 Query: 239 LGGSDPQHYQGNFHYVSI-SKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPT 297 G D Y G+ Y ++ +K W+ T G +VGS T + DTG++ + P Sbjct: 171 FGFIDTTAYTGSITYTAVSTKQGFWEWTSTGYAVGSGTFKSTS-IDGIADTGTTLLYLPA 229 Query: 298 SSLKLIMQALGAKE--KRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRD 355 + + + + + YV CS TLP +F +G + + Sbjct: 230 TVVSAYWAQVSGAKSSSSVGGYVFPCS--ATLPSFTFGVGSARIVIPGDYIDFGPISTGS 287 Query: 356 KLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFD-RHNNRIGFA 399 C + + + + G ++ + F+ +GFA Sbjct: 288 SSCFGGIQS----SAGIGINIFGDVALKAAFVVFNGATTPTLGFA 328 >1WKR-A nrPDB Length = 340 Score = 207 bits (527), Expect = 6e-54, Method: Composition-based stats. Identities = 85/347 (24%), Positives = 150/347 (43%), Gaps = 40/347 (11%) Query: 72 SPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESS 131 V TN L Y +G+G+P T+ ++ DTGS+N W+ + K S ++S Sbjct: 3 GSVPATNQL-VDYVVNVGVGSPATTYSLLVDTGSSNTWLGADK-----------SYVKTS 50 Query: 132 DSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGV 191 SS+ + ++ YGSG G D+VT+G +T+ + V DG+ Sbjct: 51 TSSATSD---KVSVTYGSGSFSGTEYTDTVTLGSLTIPKQSIGVASRDS---GFDGVDGI 104 Query: 192 LGMGFPAQAVGGVTP--------VFDHILSQGVLKEEVFSVYY--NRGSHLLGGEVVLGG 241 LG+G VG ++P V D++ SQG + + +V + GE+ G Sbjct: 105 LGVGPVDLTVGTLSPHTSTSIPTVTDNLFSQGTIPTNLLAVSFEPTTSESSTNGELTFGA 164 Query: 242 SDPQHYQGNFHYVSISK----TDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPT 297 +D Y G+ Y I+ + W I + + GSST + A +VDTG++ + Sbjct: 165 TDSSKYTGSITYTPITSTSPASAYWGIN-QSIRYGSSTSILSS-TAGIVDTGTTLTLIAS 222 Query: 298 SSLKLIMQALGA-KEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQ---YPNR 353 + +A GA + + +Q L + F +GG+ + L++ + Sbjct: 223 DAFAKYKKATGAVADNNTGLLRLTTAQYANLQSLFFTIGGQTFELTANAQIWPRNLNTAI 282 Query: 354 RDKLCTLALHAMDIPPPTGP--VWVLGATFIRKFYTEFDRHNNRIGF 398 ++ L D+ +G ++ G TF+ +FY+ +D N R+G Sbjct: 283 GGSASSVYLIVGDLGSDSGEGLDFINGLTFLERFYSVYDTTNKRLGL 329 >4OD9-A nrPDB Length = 103 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 60/99 (60%), Positives = 75/99 (75%) Query: 65 PSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGI 124 P++T P VL NY++ QYYGEIGIGTPPQ F V+FDTGS+NLWVPS C L +AC I Sbjct: 1 PAVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWI 60 Query: 125 HSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTV 163 H Y S SS+Y++NG+ F IHYGSG + G+LSQD+V+V Sbjct: 61 HHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSV 99 >4ZL4-A nrPDB Length = 444 Score = 142 bits (358), Expect = 3e-34, Method: Composition-based stats. Identities = 84/424 (19%), Positives = 143/424 (33%), Gaps = 127/424 (29%) Query: 84 YYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIH-----SLYESSDSSS-YM 137 Y+ +I IGTP Q +I DTGS++L P C CG+H +L S SS Y Sbjct: 30 YFLDIDIGTPEQRISLILDTGSSSLSFPCAGCKN----CGVHMENPFNLNNSKTSSILYC 85 Query: 138 EN------------GSDFTIHYGSGR-VKGFLSQDSVTVGG-----ITVTQTFG-EVTEL 178 EN ++ Y G + GF D V+V +T + G + E Sbjct: 86 ENEECPFKLNCVKGKCEYMQSYCEGSQISGFYFSDVVSVVSYNNERVTFRKLMGCHMHEE 145 Query: 179 PLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVV 238 L F+ + GVLGM G+ + + ++VF++ + GGE++ Sbjct: 146 SL--FLYQQATGVLGMSLSKPQ--GIPTFVNLLFDNAPQLKQVFTICISEN----GGELI 197 Query: 239 LGGSDPQHY-----------QGN-----------------------FHYVSISKTDSWQI 264 GG DP + QG+ + ++++ + I Sbjct: 198 AGGYDPAYIVRRGGSKSVSGQGSGPVSESLSESGEDPQVALREAEKVVWENVTRKYYYYI 257 Query: 265 TMKGVS-VGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLI-------------------- 303 ++G+ G++ + +G ++VD+GS+F P + Sbjct: 258 KVRGLDMFGTNMMSSSKGLEMLVDSGSTFTHIPEDLYNKLNYFFDILCIQDMNNAYDVNK 317 Query: 304 -----MQALGAKEKRIEEYV-------------------VNCSQV-PTLPDISFDL-GGR 337 ++ + +++ V C + LPD+ L Sbjct: 318 RLKMTNESFNNPLVQFDDFRKSLKSIIAKENMCVKIVDGVQCWKYLEGLPDLFVTLSNNY 377 Query: 338 AYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIG 397 Y+ + + I +LG TF + FD NRIG Sbjct: 378 KMKWQPHSYLYKKES---------FWCKGIEKQVNNKPILGLTFFKNRQVIFDIQKNRIG 428 Query: 398 FALA 401 F A Sbjct: 429 FVDA 432 >1B5F-B nrPDB Length = 87 Score = 111 bits (277), Expect = 7e-25, Method: Composition-based stats. Identities = 31/87 (35%), Positives = 50/87 (57%), Gaps = 1/87 (1%) Query: 315 EEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPV 374 EE V+C+ + ++P++SF +GG+ + L+ Y+L+ C AMD GP+ Sbjct: 1 EELQVDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMD-ATLLGPL 59 Query: 375 WVLGATFIRKFYTEFDRHNNRIGFALA 401 W+LG F+R ++T FD N +GFA A Sbjct: 60 WILGDVFMRPYHTVFDYGNLLVGFAEA 86 >4PPH-A nrPDB Length = 417 Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 59/380 (15%), Positives = 113/380 (29%), Gaps = 92/380 (24%) Query: 92 TPPQTFKVIFDTGSANLWVPSTKCSRLYL---------ACG---IHSLYESSDSSSYMEN 139 TP ++ D +LWV ++ C H + +DS++ Sbjct: 36 TPLMQVPLLLDLNGKHLWVTCSQHYSSSTYQAPFCHSTQCSRANTHQCFTCTDSTTTRPG 95 Query: 140 ------GSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAK------ 187 G + G L+QD + + T G + ++P F A Sbjct: 96 CHNNTCGLLSSNPVTQESGLGELAQDVLAIHS-THGSKLGPMVKVPQFLFSCAPSFLAQK 154 Query: 188 -----FDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGS 242 G LG+G ++ + Q FSV +R G ++ G Sbjct: 155 GLPNNVQGALGLGQAPISLQNQLFSHFGLKRQ-------FSVCLSR-YSTSNGAILFGDI 206 Query: 243 -------------DPQHYQGNFHYVSIS--KTDSWQITMKGVSVGSSTLLCEEGCAVVVD 287 D H + Y ++ K + I + + V L+ + Sbjct: 207 NDPNNNNYIHNSLDVLH---DLVYTPLTISKQGEYFIQVNAIRVNKH-LVIPTKNPFISP 262 Query: 288 TGSSF-----------------ISAPTSSLKLIMQAL------GAKEKRIEEYVVNCSQV 324 + +S+ S ++ Q A+ K + + + C Sbjct: 263 SSTSYHGSGEIGGALITTTHPYTVLSHSIFEVFTQVFANNMPKQAQVKAVGPFGL-CYDS 321 Query: 325 PTLP------DISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLG 378 + D+ D + +SS ++++Q + L + G LG Sbjct: 322 RKISGGAPSVDLILDKNDAVWRISSENFMVQAQDGVSCL---GFVDGGVHARAGIA--LG 376 Query: 379 ATFIRKFYTEFDRHNNRIGF 398 A + + FD +R+GF Sbjct: 377 AHHLEENLVVFDLERSRVGF 396 >3AUP-A nrPDB Length = 403 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 62/369 (16%), Positives = 116/369 (31%), Gaps = 79/369 (21%) Query: 92 TPPQTFKVIFDTGSANLWVP----------------STKCSRLYL----ACGIHSLYESS 131 TP V+ D +LWV ST+CSR +C S Sbjct: 31 TPLMQVPVLVDLNGNHLWVNCEQQYSSKTYQAPFCHSTQCSRANTHQCLSCPAASR--PG 88 Query: 132 DSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGIT-VTQTFGEVTELPLIPFMLAKF-- 188 + S I +G G L +D + + TQ G + +P F A Sbjct: 89 CHKNTCGLMSTNPITQQTG--LGELGEDVLAIHATQGSTQQLGPLVTVPQFLFSCAPSFL 146 Query: 189 ---------DGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVL 239 GV G+G ++ + Q F+ +R G ++ Sbjct: 147 VQKGLPRNTQGVAGLGHAPISLPNQLASHFGLQRQ-------FTTCLSRYP-TSKGAIIF 198 Query: 240 GGSDPQHYQ-------GNFHYVS--ISKTDSWQITMKGVSVG----------SSTLLCEE 280 G + Q + + I+ + + + + + SST++ Sbjct: 199 GDAPNNMRQFQNQDIFHDLAFTPLTITLQGEYNVRVNSIRINQHSVFPLNKISSTIVGST 258 Query: 281 GCAVVVDTGSSFISAPTSSLKLIMQAL------GAKEKRIEEY--VVNCSQVPTLPDISF 332 ++ T + + S + Q A+ K + + N +++ P + Sbjct: 259 SGGTMISTSTPHMVLQQSVYQAFTQVFAQQLPKQAQVKSVAPFGLCFNSNKINAYPSVDL 318 Query: 333 DL---GGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEF 389 + G + +S D ++Q + C L + + P LGA + + F Sbjct: 319 VMDKPNGPVWRISGEDLMVQA--QPGVTC-LGVMNGGMQPRAEIT--LGARQLEENLVVF 373 Query: 390 DRHNNRIGF 398 D +R+GF Sbjct: 374 DLARSRVGF 382 >1T6G-A nrPDB Length = 381 Score = 42.3 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 30/211 (14%), Positives = 69/211 (32%), Gaps = 35/211 (16%) Query: 220 EVFSVYYNRGSHLLGGEVVLGG--SDPQHYQGNFHYVSISKTDS---WQITMKGVSVGSS 274 F + G G + GG + + Y + I+ + + VG + Sbjct: 162 NRFLLCLPTGG---PGVAIFGGGPVPWPQFTQSMPYTPLVTKGGSPAHYISARSIVVGDT 218 Query: 275 TLLCEEGCAV----------------------VVDTGSSFISAPTSSLKLIMQALGAKEK 312 + EG ++D + ++A ++ + +A+ A Sbjct: 219 RVPVPEGALATGGVMLSTRLPYVLLRPDVYRPLMDAFTKALAAQHANGAPVARAVEAVAP 278 Query: 313 RIEEYVVNC--SQVPT--LPDISFDL-GGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDI 367 Y + + +P++ L GG +T++ + ++ + + + + Sbjct: 279 FGVCYDTKTLGNNLGGYAVPNVQLGLDGGSDWTMTGKNSMVDVKQGTACVAFVEMKGVAA 338 Query: 368 PPPTGPVWVLGATFIRKFYTEFDRHNNRIGF 398 P +LG + F +FD R+GF Sbjct: 339 GDGRAPAVILGGAQMEDFVLDFDMEKKRLGF 369 >3HD8-A nrPDB Length = 389 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 45/324 (13%), Positives = 94/324 (29%), Gaps = 52/324 (16%) Query: 111 PSTKCSRLYLACGIHSL----YESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGI 166 P+ C H Y S+ + GS F + + G V + Sbjct: 64 PAPGCPAPSCGSDRHDKPCTAYPSNPVTGACAAGSLFHTRFAANTTDGNK-----PVSEV 118 Query: 167 TVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYY 226 V L GV G+ A+ ++ F + Sbjct: 119 NVRVLAACAPSKLLASLPRGS-TGVAGLAGSGLALPSQ-------VASAQKVPNKFLLCL 170 Query: 227 NRGSHLLGGEVVLGG--SDPQHYQGNFHYVSISKTDS---WQITMKGVSVGSSTLLCEEG 281 G G + GG + + Y + I+ + + V ++ + E Sbjct: 171 PTGG---PGVAIFGGGPLPWPQFTQSMDYTPLVAKGGSPAHYISARSIKVENTRVPISER 227 Query: 282 CAV----------------------VVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVV 319 +VD + ++A ++ + +A+ Y Sbjct: 228 ALATGGVMLSTRLPYVLLRRDVYRPLVDAFTKALAAQPANGAPVARAVKPVAPFELCYDT 287 Query: 320 -NCSQVPT---LPDISFDL-GGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPV 374 P +P++ +L GG + ++ + ++ + + + +D + P Sbjct: 288 KTLGNNPGGYWVPNVLLELDGGSDWAMTGKNSMVDVKPGTACVAFVEMKGVDAGDGSAPA 347 Query: 375 WVLGATFIRKFYTEFDRHNNRIGF 398 +LG + F +FD R+GF Sbjct: 348 VILGGAQMEDFVLDFDMEKKRLGF 371 >3Q31-A nrPDB Length = 244 Score = 32.7 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 28/86 (32%), Gaps = 14/86 (16%) Query: 184 MLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSD 243 AK V+G F VG P+FD + + + G+ G++ GG Sbjct: 121 TAAKETAVVGFFFQLSEVGDSVPLFDSVF--APIDN-----IPDAGTSTTTGQLDFGGLL 173 Query: 244 PQH-------YQGNFHYVSISKTDSW 262 Y G+ ++ W Sbjct: 174 DHFNRHGVYQYTGSLTTPPCTEEVMW 199 >2BKL-A nrPDB Length = 695 Score = 32.3 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 36/102 (35%), Gaps = 13/102 (12%) Query: 63 KRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLAC 122 + P + ++ + L + L+ YY TP Q +K TG + LW Sbjct: 358 QLPGVGAASNLMGLED-LDDAYYVFTSFTTPRQIYKTSVSTGKSELW-AKVDVPMNPEQY 415 Query: 123 GIHSLYESSDSSSY-----------MENGSDFTIHYGSGRVK 153 + ++ +S + +G+ T+ YG G Sbjct: 416 QVEQVFYASKDGTKVPMFVVHRKDLKRDGNAPTLLYGYGGFN 457 >3VLB-A nrPDB Length = 413 Score = 31.9 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 69/420 (16%), Positives = 124/420 (29%), Gaps = 110/420 (26%) Query: 64 RPSLTNLTSPVVLTNYLNT-QYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLAC 122 +PS V + +T QY I TP + ++ D G LWV C + Y+ Sbjct: 1 QPSFRPSALVVPVKKDASTLQYVTTINQRTPLVSENLVVDLGGRFLWV---DCDQNYV-- 55 Query: 123 GIHSLYESSDSSSYMENGSDFTIHYGSGRVK----------------------------- 153 SS+Y + SG + Sbjct: 56 ----------SSTYRPVRCRTSQCSLSGSIACGDCFNGPRPGCNNNTCGVFPENPVINTA 105 Query: 154 --GFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAK-------FDGVLGMGFPAQAVGGV 204 G +++D V+V T + G V +P F A GV+GM + + Sbjct: 106 TGGEVAEDVVSVES-TDGSSSGRVVTVPRFIFSCAPTSLLQNLASGVVGMAGLGRTRIAL 164 Query: 205 TPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHY-------QGNFHYVSI- 256 F S + F++ + GS ++ G DP + Y + Sbjct: 165 PSQFASAFS----FKRKFAMCLS-GSTSSNSVIIFGN-DPYTFLPNIIVSDKTLTYTPLL 218 Query: 257 --------SKTDS-----WQITMKGVSVGSSTLLCEEGCAVVVDTG---------SSFIS 294 + T + I +K + + S + + G + + Sbjct: 219 TNPVSTSATSTQGEPSVEYFIGVKSIKINSKIVALNTSLLSISSAGLGGTKISTINPYTV 278 Query: 295 APTSSLKLIMQAL---GAKEK-------------RIEEYVVNCSQVPTLPDISFDLGGRA 338 TS K + +A A + +++ P++P I L + Sbjct: 279 LETSIYKAVTEAFIKESAARNITRVASVAPFGACFSTDNILSTRLGPSVPSIDLVLQSES 338 Query: 339 YTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGF 398 + T + +C L +D V+G + +FD +R+GF Sbjct: 339 VVWTITGSNSMVYINDNVVC---LGVVDGGSNLRTSIVIGGHQLEDNLVQFDLATSRVGF 395 >5U47-A nrPDB Length = 707 Score = 31.5 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 57/171 (33%), Gaps = 15/171 (8%) Query: 150 GRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGV-LGMGFPAQAVGGVTPVF 208 G G +SQ+SV + + Q L F +G+ L F Q Sbjct: 390 GESSGIVSQNSVNIAQSSFGQGISVTQVQMLRAFTAISNNGIMLEPQFIKQVADTNKGTV 449 Query: 209 DHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKG 268 + V+ + V + + ++ G+DP+ G Y + Q+ Sbjct: 450 RTAKKE-VIGKPV----SKQAASETRNYMISVGTDPEF--GTL-YNKSEGSPIIQVGNND 501 Query: 269 VSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVV 319 V+V S T + G++ +L ++ + +++ YV Sbjct: 502 VTVKSGTAQVPDEKTGTYKVGTN------ETLNSVVAMVPSEDPEYIMYVT 546 >3OS6-A nrPDB Length = 399 Score = 31.5 bits (70), Expect = 0.69, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 1/75 (1%) Query: 243 DPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSS-LK 301 D + + G + ++ W +T++ V +TL G VV ++ A TS+ + Sbjct: 324 DREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSAKFQ 383 Query: 302 LIMQALGAKEKRIEE 316 +++ALG + + E Sbjct: 384 TMLKALGLNDSSLNE 398 >2D81-A nrPDB Length = 318 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 30/88 (34%), Gaps = 1/88 (1%) Query: 288 TGSSFISAPTSSLKLIMQALGAKEKRIEE-YVVNCSQVPTLPDISFDLGGRAYTLSSTDY 346 TGSS + + + + LG + YV V T P G + +LS++ Y Sbjct: 97 TGSSDTTVGPNVMNQLKAQLGNFDNSANVSYVTTTGAVHTFPTDFNGAGDNSCSLSTSPY 156 Query: 347 VLQYPNRRDKLCTLALHAMDIPPPTGPV 374 + ++ TG + Sbjct: 157 ISNCNYDGAGAALKWIYGSLNARNTGTL 184 >5B8F-A nrPDB Length = 164 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 16/37 (43%) Query: 159 DSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMG 195 D +T+GG+ + G V + A D +LG Sbjct: 23 DFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAA 59 >5OR1-A nrPDB Length = 804 Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 17/33 (51%), Gaps = 3/33 (9%) Query: 233 LGGEVVLGGSDPQHYQGNF---HYVSISKTDSW 262 L G+V + GSD ++Y+ + YV I W Sbjct: 591 LTGKVTIPGSDNEYYKVSLDTATYVPIDNDHKW 623 Score = 29.2 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 59/160 (36%), Gaps = 20/160 (12%) Query: 72 SPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYE-- 129 L++Y N Y ++ +G P + + A L K S + + E Sbjct: 497 DDADLSDYTNKSYGTDVTLGFPINEYNTL----RAGLGYVHNKLSNMQPQIAMDRYLESM 552 Query: 130 --SSDSSSYMENGSDFTIHYGSGRV-KGFLSQDSVTV---GGITVTQTFGEVTELPLIPF 183 S+D+SS+ + F + ++ +G+ D V G +T+ + E ++ L Sbjct: 553 GQSADTSSFAADDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVSLDTA 612 Query: 184 MLAKFD-----GVLG---MGFPAQAVGGVTPVFDHILSQG 215 D VLG G+ G P +++ + G Sbjct: 613 TYVPIDNDHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGG 652 >5I24-A nrPDB Length = 836 Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 35/225 (15%), Positives = 69/225 (30%), Gaps = 25/225 (11%) Query: 140 GSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQ 199 G + YG G +S+ T GG+ ++ L+ F D LG GF Sbjct: 442 GFVGSQRYGMIPWTGDVSR---TWGGLA--SQVELALQMSLLGFGYIHSD--LG-GFAD- 492 Query: 200 AVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFH-----YV 254 + Q + + V Y G + E V + + + Sbjct: 493 -GETLDKEMYIRWLQYGVFQPV---YRPHGQDHIPSEPVFQDEETKAILRPLVKLRYRML 548 Query: 255 SISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQA--LGAKEK 312 T ++Q T+ G+ + +E ++D +S+ + + I QA Sbjct: 549 PYIYTAAYQNTLTGMPLMRPLFFSDEKNPALIDNKTSYFWGDSLLVTPITQAGVESVSIP 608 Query: 313 RIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKL 357 + + + D + G TL + + + + Sbjct: 609 APKGVWFDFWK-----DTRYQTDGAPLTLPTDLHTIPVLVKAGAF 648 >3SOK-A nrPDB Length = 151 Score = 29.2 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 14/35 (40%) Query: 128 YESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVT 162 Y ++ +NG I YG G +S+ V Sbjct: 84 YNKDAKTADEKNGCKVVITYGQGTAGEKISKLIVG 118 >1IGA-A nrPDB Length = 475 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 93 PPQTFKVIFDTGSANLWVPSTKC-SRLYLACGIHSLYESSD 132 P Q T S+ L +P+T+C + + C + S Sbjct: 177 PSQDASGDLYTTSSQLTLPATQCLAGKSVTCHVKHYTNPSQ 217 >4XVZ-A nrPDB Length = 283 Score = 28.1 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 21/57 (36%), Gaps = 3/57 (5%) Query: 127 LYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPF 183 ++S+ S S G + + V F+ QD+ V G+ F E + Sbjct: 19 YFQSNASPS---TGVELYLDLLKRTVSNFIYQDATHVAGLITEAAFVEEARESGEDY 72 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.138 0.395 Lambda K H 0.267 0.0421 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,712,589 Number of Sequences: 36641 Number of extensions: 686722 Number of successful extensions: 2309 Number of sequences better than 10.0: 79 Number of HSP's better than 10.0 without gapping: 123 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1644 Number of HSP's gapped (non-prelim): 206 length of query: 402 length of database: 10,336,785 effective HSP length: 99 effective length of query: 303 effective length of database: 6,709,326 effective search space: 2032925778 effective search space used: 2032925778 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)