BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05937 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2G9B-A nrPDB 521 e-148 2Q4U-A nrPDB 182 1e-46 5UKG-A nrPDB 51 4e-07 5A2H-A nrPDB 51 6e-07 1GGZ-A nrPDB 50 8e-07 6HCS-A nrPDB 49 2e-06 6O20-F nrPDB 48 4e-06 4I2Y-A nrPDB 47 7e-06 1CLM-A nrPDB 47 8e-06 3WFN-B nrPDB 47 9e-06 2F2P-A nrPDB 47 9e-06 3U0K-A nrPDB 47 9e-06 3K21-A nrPDB 47 1e-05 4E53-A nrPDB 47 1e-05 2N6A-A nrPDB 46 1e-05 4OY4-A nrPDB 46 2e-05 2TN4-A nrPDB 46 2e-05 3EK4-A nrPDB 46 2e-05 5XND-A nrPDB 45 2e-05 1TOP-A nrPDB 45 3e-05 4IL1-A nrPDB 45 3e-05 4JWQ-A nrPDB 44 6e-05 5I0I-E nrPDB 44 7e-05 2LMV-A nrPDB 43 2e-04 5E37-A nrPDB 42 2e-04 3O4Y-A nrPDB 42 2e-04 1BJF-A nrPDB 42 3e-04 2L1W-A nrPDB 42 4e-04 6EPA-A nrPDB 41 4e-04 2LCP-A nrPDB 41 5e-04 2R2I-A nrPDB 41 6e-04 2LC5-A nrPDB 41 6e-04 3QRX-A nrPDB 41 6e-04 5CPV-A nrPDB 40 9e-04 5T7C-A nrPDB 40 0.001 2NLN-A nrPDB 40 0.001 3KF9-A nrPDB 40 0.001 1BU3-A nrPDB 39 0.002 4DS7-A nrPDB 39 0.003 5ZGM-A nrPDB 38 0.003 2LHI-A nrPDB 38 0.004 5M6C-E nrPDB 38 0.004 5D43-A nrPDB 38 0.004 1LKJ-A nrPDB 38 0.005 4RGJ-A nrPDB 38 0.005 2I94-A nrPDB 38 0.005 2D8N-A nrPDB 37 0.006 1S6I-A nrPDB 37 0.006 2LHH-A nrPDB 37 0.006 5PAL-A nrPDB 37 0.006 3PAT-A nrPDB 37 0.006 5ZH6-A nrPDB 37 0.007 1A75-A nrPDB 37 0.008 1JBA-A nrPDB 37 0.008 2OBH-A nrPDB 37 0.010 2GGM-A nrPDB 37 0.010 2MBX-A nrPDB 37 0.011 2GGZ-A nrPDB 36 0.017 2LAP-A nrPDB 36 0.017 1Y1X-A nrPDB 36 0.017 1G33-A nrPDB 36 0.018 2NA0-A nrPDB 36 0.018 2RO9-A nrPDB 35 0.022 5B8I-B nrPDB 35 0.025 1GGW-A nrPDB 35 0.025 3NCG-A nrPDB 35 0.029 2KQY-A nrPDB 35 0.030 2KYF-A nrPDB 35 0.032 2BL0-C nrPDB 35 0.037 1JC2-A nrPDB 35 0.037 1RTP-1 nrPDB 35 0.038 3KHE-A nrPDB 35 0.044 1FW4-A nrPDB 35 0.044 1V1G-A nrPDB 35 0.045 4PAL-A nrPDB 35 0.046 3I5H-B nrPDB 35 0.047 4OKH-A nrPDB 34 0.053 3L19-A nrPDB 34 0.056 1RK9-A nrPDB 34 0.057 2JNF-A nrPDB 34 0.064 3HZT-A nrPDB 34 0.069 5JOJ-A nrPDB 34 0.075 3LIJ-A nrPDB 34 0.082 5JOL-A nrPDB 33 0.088 2K2A-A nrPDB 33 0.099 2I08-A nrPDB 33 0.099 1DTL-A nrPDB 33 0.10 5COC-A nrPDB 33 0.10 4ORC-B nrPDB 33 0.11 5ZOR-A nrPDB 33 0.13 2ZFD-A nrPDB 33 0.13 2LV7-A nrPDB 33 0.15 3I5I-C nrPDB 33 0.16 5MKE-A nrPDB 33 0.17 5OTJ-D nrPDB 33 0.17 2KZ2-A nrPDB 32 0.19 1YX7-A nrPDB 32 0.21 2NCO-A nrPDB 32 0.23 1OZS-A nrPDB 32 0.23 1F55-A nrPDB 32 0.23 2HF5-A nrPDB 32 0.25 2KN2-A nrPDB 32 0.25 3AAJ-A nrPDB 32 0.26 1UHN-A nrPDB 32 0.26 2M5E-A nrPDB 32 0.27 4Q57-A nrPDB 32 0.29 3IFK-A nrPDB 32 0.31 2AMI-A nrPDB 32 0.32 5JN2-A nrPDB 32 0.35 2LVK-A nrPDB 32 0.38 2ROB-A nrPDB 32 0.39 3Q5I-A nrPDB 31 0.46 5YPX-A nrPDB 31 0.49 2RO8-A nrPDB 31 0.54 3DTP-E nrPDB 31 0.56 1ZMZ-A nrPDB 31 0.59 5H7D-E nrPDB 31 0.68 3FWC-A nrPDB 30 0.71 1TRF-A nrPDB 30 0.77 1SR6-C nrPDB 30 0.80 3DD4-A nrPDB 30 0.85 1TNP-A nrPDB 30 0.89 2K7C-A nrPDB 30 1.0 1OQP-A nrPDB 30 1.0 2JU0-A nrPDB 30 1.3 1C7W-A nrPDB 30 1.3 2M97-A nrPDB 30 1.5 2B1U-A nrPDB 30 1.5 2AAO-A nrPDB 29 1.6 5MWC-D nrPDB 29 1.7 5TBY-E nrPDB 29 1.8 3AKA-A nrPDB 29 2.0 1TTX-A nrPDB 29 2.1 6DU8-A nrPDB 29 2.2 5VE9-A nrPDB 29 2.4 2M8U-A nrPDB 28 2.9 4WPX-A nrPDB 28 3.0 5XXB-F nrPDB 28 3.0 4YZB-A nrPDB 28 3.1 2FGE-A nrPDB 28 3.1 5XJC-J nrPDB 28 3.5 3J04-B nrPDB 28 3.5 4N5X-A nrPDB 28 3.5 1P2Z-A nrPDB 28 3.6 4ZCV-A nrPDB 28 3.9 2KLD-A nrPDB 28 4.1 1S1E-A nrPDB 28 4.1 2KQ6-A nrPDB 28 4.3 1S6C-A nrPDB 28 4.3 2L2E-A nrPDB 28 4.4 2M29-A nrPDB 28 4.4 6D1W-A nrPDB 28 4.7 2KSZ-A nrPDB 28 4.7 1R9Q-A nrPDB 27 6.0 4OCI-A nrPDB 27 6.4 3JBH-C nrPDB 27 6.7 6IIE-A nrPDB 27 7.1 3MZL-B nrPDB 27 7.2 3BOW-B nrPDB 27 7.4 1QXP-A nrPDB 27 8.1 3VF1-A nrPDB 27 8.8 2E6W-A nrPDB 27 9.0 1NP8-A nrPDB 27 9.0 1KFU-L nrPDB 27 9.5 6HLX-A nrPDB 27 9.6 >2G9B-A nrPDB Length = 263 Score = 521 bits (1341), Expect = e-148, Method: Compositional matrix adjust. Identities = 257/261 (98%), Positives = 259/261 (99%) Query: 1 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKT 60 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQEL QARKKAGLELSPEMKT Sbjct: 3 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKT 62 Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET Sbjct: 63 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 122 Query: 121 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 180 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK Sbjct: 123 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 182 Query: 181 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMA 240 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQ+LDINNI+TYKKNIMA Sbjct: 183 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQELDINNISTYKKNIMA 242 Query: 241 LSDGGKLYRTDLALILCAGDN 261 LSDGGKLYRTDLALIL AGDN Sbjct: 243 LSDGGKLYRTDLALILSAGDN 263 >2Q4U-A nrPDB Length = 272 Score = 182 bits (462), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 105/259 (40%), Positives = 159/259 (61%), Gaps = 13/259 (5%) Query: 11 ITASQFFEIWLHFDADGSGYLEGKEL----QNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + A+ F +IW HFDAD +GY+EGKEL ++++++LQ K + K+F+ Y Sbjct: 8 LDAAGFLQIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYD 67 Query: 67 QRDDGKIGIVELAH-VLPTEENFLLLFRCQ-QLKSCEEFMKTWRKYDTDHSGFIETEELK 124 DG++ I ELA+ +LP EENFLL+FR + L + EFMK WRKYD D SG+I ELK Sbjct: 68 ATFDGRLQIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELK 127 Query: 125 NFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGI 184 NFLKDL + K + KL EYTD M+K+FD N DG+L+L ++AR+L +QENFLL+F+ Sbjct: 128 NFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMD 187 Query: 185 KMC----GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMA 240 ++F K F YD G ++ E+D +KD+ E + + ++ +++ ++ Sbjct: 188 ASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDMMELVRPSISGGDLDKFRECLLT 247 Query: 241 LSD---GGKLYRTDLALIL 256 D GK+ +++LAL L Sbjct: 248 HCDMNKDGKIQKSELALCL 266 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 49/167 (29%), Positives = 92/167 (55%), Gaps = 5/167 (2%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQE--LQQARKKAGLELSPEMKTFVDQ 64 ++ L + +F +IW +DAD SGY+ EL+N +++ LQ +K +L + Sbjct: 97 EAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKI 156 Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFR---CQQLKSCEEFMKTWRKYDTDHSGFIETE 121 + + DG++ + +LA +L +ENFLL F+ Q++ +F K + YD +G +E Sbjct: 157 FDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGP 216 Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMA 168 E+ F+KD++E ++ L ++ + +L D N DGK++ +E+A Sbjct: 217 EVDGFVKDMMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSELA 263 >5UKG-A nrPDB Length = 419 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 60/120 (50%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ DG Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGDGT 333 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 + E ++ + ++ ++ +E +AF ++D+DGNGYI EL ++ DL EK Sbjct: 334 FDFPEFLTMMARKMSY-------RVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEK 386 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 38/158 (24%), Positives = 74/158 (46%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A E++ +++ DG Sbjct: 281 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGDGTF 334 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E ++ + + +R + EE + +R +D D +G+I EL++ + DL EK Sbjct: 335 DFPEFLTMMARK----MSYRVTE----EEIREAFRVFDKDGNGYIGAAELRHVMTDLGEK 386 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M+++ D + DG++ E +++ Sbjct: 387 LTD--------EEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 27.7 bits (60), Expect = 5.2, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 23/38 (60%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQ 45 S +T + E + FD DG+GY+ EL++++ +L + Sbjct: 348 SYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGE 385 >5A2H-A nrPDB Length = 149 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 S+F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 11 SEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 61 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L L+ + + S EE + +R +D D +GFI EL++ + +L EK Sbjct: 62 GTIDFPEFLN-----LMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEK 116 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M++ D + DG++ E +++ Sbjct: 117 LTD--------EEVDEMIREADVDGDGQINYEEFVKVM 146 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 12 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 63 Query: 162 LELTE----MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ E MAR + ++ +E +AF ++D+D NG+I EL ++ + Sbjct: 64 IDFPEFLNLMARKMKDTDS-----------EEELKEAFRVFDKDQNGFISAAELRHVMTN 112 Query: 218 LCEK 221 L EK Sbjct: 113 LGEK 116 >1GGZ-A nrPDB Length = 148 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 40/159 (25%), Positives = 75/159 (47%), Gaps = 22/159 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + +EL +++ L Q +A L +M + +D+ G Sbjct: 9 VTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELR---DMMSEIDRDGN----- 60 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 G V+ L ++ + + + EE + +R +D D +GF+ EL++ + L E Sbjct: 61 -GTVDFPEFLG-----MMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGE 114 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 K + E D M++ D++ DG++ E R+L Sbjct: 115 KLSD--------EEVDEMIRAADTDGDGQVNYEEFVRVL 145 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T EL ++ L + + AE D+M ++ D + +G Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTE-------AELRDMMSEI-DRDGNGT 62 Query: 162 LELTE----MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ E MAR + +N +E +AF ++D+DGNG++ EL ++ Sbjct: 63 VDFPEFLGMMARKMKDTDN-----------EEEIREAFRVFDKDGNGFVSAAELRHVMTR 111 Query: 218 LCEK 221 L EK Sbjct: 112 LGEK 115 >6HCS-A nrPDB Length = 167 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 41/161 (25%), Positives = 75/161 (46%), Gaps = 22/161 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 61 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++F+ +L EK Sbjct: 62 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEK 116 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 E D M++ D + DG++ E +++ + Sbjct: 117 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 149 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 63 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL + + Sbjct: 64 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHFMTN 112 Query: 218 LCEK 221 L EK Sbjct: 113 LGEK 116 >6O20-F nrPDB Length = 169 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 43/173 (24%), Positives = 78/173 (45%), Gaps = 24/173 (13%) Query: 4 SHLQSSLI--TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTF 61 SH+ L ++F E + FD DG G + KEL +++ L Q +A L+ +M Sbjct: 19 SHMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINE 75 Query: 62 VDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETE 121 VD G G ++ L ++ + + S EE + +R +D D +G+I Sbjct: 76 VDADGN------GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAA 124 Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 EL++ + +L EK E D M++ D + DG++ E +++ + Sbjct: 125 ELRHVMTNLGEKLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 169 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 32 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 83 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL ++ + Sbjct: 84 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHVMTN 132 Query: 218 LCEK 221 L EK Sbjct: 133 LGEK 136 >4I2Y-A nrPDB Length = 421 Score = 47.4 bits (111), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ DG Sbjct: 284 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGDGT 335 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 + E ++ + N +E +AF ++D+DGNGYI EL ++ DL EK Sbjct: 336 FDFPEFLTMMARKMN-------DTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEK 388 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A E++ +++ DG Sbjct: 283 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGDGTF 336 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E ++ + N S EE + +R +D D +G+I EL++ + DL EK Sbjct: 337 DFPEFLTMMARKMN--------DTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEK 388 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M+++ D + DG++ E +++ Sbjct: 389 LTD--------EEVDEMIRVADIDGDGQVNYEEFVQMM 418 >1CLM-A nrPDB Length = 148 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 10 AEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 60 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L L+ + ++ S EE ++ ++ +D D +G I EL++ + +L E Sbjct: 61 GTIDFPEFLS-----LMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGE- 114 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 K DD D M++ D + DG + E R++ Sbjct: 115 --KLTDDE-----VDEMIREADIDGDGHINYEEFVRMM 145 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 62 Query: 162 LELTE----MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ E MAR + Q+ +E +AF+++D+DGNG I EL ++ + Sbjct: 63 IDFPEFLSLMARKMKEQD-----------SEEELIEAFKVFDRDGNGLISAAELRHVMTN 111 Query: 218 LCEK 221 L EK Sbjct: 112 LGEK 115 >3WFN-B nrPDB Length = 182 Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 22/161 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 17 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 67 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 68 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 122 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 E D M++ D + DG++ E +++ + Sbjct: 123 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 155 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 18 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 69 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL ++ + Sbjct: 70 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHVMTN 118 Query: 218 LCEK 221 L EK Sbjct: 119 LGEK 122 >2F2P-A nrPDB Length = 179 Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 22/161 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 61 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 62 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 116 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 E D M++ D + DG++ E +++ + Sbjct: 117 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 149 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 63 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL ++ + Sbjct: 64 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHVMTN 112 Query: 218 LCEK 221 L EK Sbjct: 113 LGEK 116 >3U0K-A nrPDB Length = 442 Score = 46.6 bits (109), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 40/160 (25%), Positives = 74/160 (46%), Gaps = 26/160 (16%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A E++ +++ DG I Sbjct: 304 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGDGTI 357 Query: 74 GIVELAHVLPTEENFLLLF--RCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 E FL++ + + S EE + +R +D D +G+I EL++ + +L Sbjct: 358 DFPE----------FLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 407 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 EK E D M++ D + DG++ E +++ Sbjct: 408 EKLTD--------EEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ DG Sbjct: 305 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGDGT 356 Query: 162 LELTE----MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ E MAR + ++ +E +AF ++D+DGNGYI EL ++ + Sbjct: 357 IDFPEFLIMMARKMKDTDS-----------EEEIREAFRVFDKDGNGYISAAELRHVMTN 405 Query: 218 LCEK 221 L EK Sbjct: 406 LGEK 409 >3K21-A nrPDB Length = 191 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 42/155 (27%), Positives = 69/155 (44%), Gaps = 22/155 (14%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE-L 78 +L D DG GY+ ++L++ +K GL+L +DQ GKI E + Sbjct: 58 FLVLDEDGKGYITK-------EQLKKGLEKDGLKLPYNFDLLLDQIDSDGSGKIDYTEFI 110 Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV 138 A L ++ L C +R +D D+ G I T EL + L + +K N T Sbjct: 111 AAALDRKQLSKKLIYC-----------AFRVFDVDNDGEITTAELAHILYNGNKKGNITQ 159 Query: 139 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 D + M++ D NNDGK++ E + ++ + Sbjct: 160 RDVNRVKR---MIRDVDKNNDGKIDFHEFSEMMKL 191 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 48/178 (26%), Positives = 77/178 (43%), Gaps = 32/178 (17%) Query: 80 HVLPTEENFLLLFRCQQLK-----------SCEEFMKTWRKYDTDHSGFIETEELKNFLK 128 HVL +N+ LL + Q+L E+ T+ D D G+I E+LK L+ Sbjct: 20 HVLENFKNYGLLLKFQKLAMTIIAQQSNDYDVEKLKSTFLVLDEDGKGYITKEQLKKGLE 79 Query: 129 DLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE-MARLLPVQENFLLKFQGIKMC 187 D KL DL+L DS+ GK++ TE +A L ++ + Sbjct: 80 K---------DGLKLPYNFDLLLDQIDSDGSGKIDYTEFIAAALDRKQ----------LS 120 Query: 188 GKEFNKAFELYDQDGNGYIDENELDALLKDLCEK-NKQDLDINNITTYKKNIMALSDG 244 K AF ++D D +G I EL +L + +K N D+N + +++ +DG Sbjct: 121 KKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGNITQRDVNRVKRMIRDVDKNNDG 178 >4E53-A nrPDB Length = 185 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 18 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 68 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 69 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 123 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M++ D + DG++ E +++ Sbjct: 124 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 70 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL ++ + Sbjct: 71 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHVMTN 119 Query: 218 LCEK 221 L EK Sbjct: 120 LGEK 123 >2N6A-A nrPDB Length = 173 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 12 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 62 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 63 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 117 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M++ D + DG++ E +++ Sbjct: 118 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMM 147 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 64 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL ++ + Sbjct: 65 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHVMTN 113 Query: 218 LCEK 221 L EK Sbjct: 114 LGEK 117 >4OY4-A nrPDB Length = 415 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 22/161 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A E++ +++ DG I Sbjct: 18 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGDGTI 71 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 72 DFPEFLT--------MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 123 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 E D M++ D + DG++ E +++ + Sbjct: 124 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 156 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ DG Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGDGT 70 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + ++ +E +AF ++D+DGNGYI EL ++ + Sbjct: 71 IDFPEFLTMMARKMKDTDS-----------EEEIREAFRVFDKDGNGYISAAELRHVMTN 119 Query: 218 LCEK 221 L EK Sbjct: 120 LGEK 123 >2TN4-A nrPDB Length = 159 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 44/175 (25%), Positives = 81/175 (46%), Gaps = 31/175 (17%) Query: 2 AESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTF 61 A S+L +I ++F + FDADG G + KEL +++ L Q K E+ Sbjct: 7 ARSYLSEEMI--AEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTK------EELDAI 58 Query: 62 VDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQ-----QLKSCEEFMKTWRKYDTDHSG 116 +++ + G I E FL++ Q + KS EE + +R +D + G Sbjct: 59 IEEVDEDGSGTIDF----------EEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADG 108 Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +I+ EEL + + + V D ++ + ++K D NNDG+++ E +++ Sbjct: 109 YIDAEELAEIFR----ASGEHVTDEEI----ESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 26/115 (22%), Positives = 50/115 (43%), Gaps = 12/115 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + +D D G I +EL ++ L + K E D +++ D + G Sbjct: 18 EFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTK--------EELDAIIEEVDEDGSGT 69 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 ++ E ++ Q +K +E + F ++D++ +GYID EL + + Sbjct: 70 IDFEEFLVMMVRQ----MKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFR 120 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCE-KNKQDLD 227 EF AF+++D DG G I EL +++ L + K++LD Sbjct: 18 EFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELD 56 >3EK4-A nrPDB Length = 451 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 22/161 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 313 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 363 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 364 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 418 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 E D M++ D + DG++ E +++ + Sbjct: 419 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 451 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 314 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 365 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL ++ + Sbjct: 366 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHVMTN 414 Query: 218 LCEK 221 L EK Sbjct: 415 LGEK 418 >5XND-A nrPDB Length = 114 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 39/117 (33%), Positives = 51/117 (43%), Gaps = 21/117 (17%) Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQL----------------KSCEEFMKTWRKYDTDH 114 G +G + A VL E L C+ KS +E K + D D Sbjct: 1 GPLGSMAFASVLKDAEVTAALDGCKAAGSFDHKKFFKACGLSGKSTDEVKKAFAIIDQDK 60 Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 SGFIE EELK FL++ A D AE T LK DS+ DGK+ + E A ++ Sbjct: 61 SGFIEEEELKLFLQNFKAGARALSD----AE-TKAFLKAGDSDGDGKIGIDEFAAMI 112 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 3/41 (7%) Query: 181 FQGIKMCGK---EFNKAFELYDQDGNGYIDENELDALLKDL 218 F+ + GK E KAF + DQD +G+I+E EL L++ Sbjct: 36 FKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNF 76 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Query: 24 DADGSGYLEGKELQNLIQELQQARKKAGLELS-PEMKTFVDQYGQRDDGKIGIVELAHVL 82 D D SG++E +EL+ +Q + + LS E K F+ DGKIGI E A ++ Sbjct: 57 DQDKSGFIEEEELKLFLQNFKAGAR----ALSDAETKAFLKAGDSDGDGKIGIDEFAAMI 112 >1TOP-A nrPDB Length = 162 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 47/175 (26%), Positives = 77/175 (44%), Gaps = 31/175 (17%) Query: 2 AESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTF 61 A + L +I ++F + FDADG G + KEL +++ L Q K E+ Sbjct: 10 ARAFLSEEMI--AEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK------EELDAI 61 Query: 62 VDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQ-----QLKSCEEFMKTWRKYDTDHSG 116 +++ + G I E FL++ Q + KS EE +R +D + G Sbjct: 62 IEEVDEDGSGTIDF----------EEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADG 111 Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 FI+ EEL L+ E + + DLM K D NNDG+++ E +++ Sbjct: 112 FIDIEELGEILRATGEHVTEE-------DIEDLM-KDSDKNNDGRIDFDEFLKMM 158 Score = 33.9 bits (76), Expect = 0.073, Method: Compositional matrix adjust. Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 12/115 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + +D D G I T+EL ++ L + K E D +++ D + G Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK--------EELDAIIEEVDEDGSGT 72 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 ++ E ++ Q +K +E F ++D++ +G+ID EL +L+ Sbjct: 73 IDFEEFLVMMVRQ----MKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILR 123 Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCE-KNKQDLD 227 EF AF+++D DG G I EL +++ L + K++LD Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELD 59 >4IL1-A nrPDB Length = 823 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 40/158 (25%), Positives = 73/158 (46%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + FD DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 11 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 61 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 62 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 116 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M++ D + DG++ E +++ Sbjct: 117 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 63 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + ++ +E +AF ++D+DGNGYI EL ++ + Sbjct: 64 IDFPEFLTMMARKMKDTDS-----------EEEIREAFRVFDKDGNGYISAAELRHVMTN 112 Query: 218 LCEK 221 L EK Sbjct: 113 LGEK 116 Score = 30.4 bits (67), Expect = 0.73, Method: Compositional matrix adjust. Identities = 41/174 (23%), Positives = 69/174 (39%), Gaps = 36/174 (20%) Query: 13 ASQFFEIWLHFDAD---------------GSGYLEGKELQNLIQELQQARKKAGLELSPE 57 AS E+ HFDAD SG L +E +L ELQQ +P Sbjct: 162 ASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQ---------NPL 211 Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGF 117 ++ +D + +G++ E + F + K ++ +R YD D G+ Sbjct: 212 VQRVIDIFDTDGNGEVDFKEFIEGVSQ-------FSVKGDKE-QKLRFAFRIYDMDKDGY 263 Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 I EL LK ++ + DT+L + D + D + DG++ E ++ Sbjct: 264 ISNGELFQVLKMMV---GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 314 >4JWQ-A nrPDB Length = 199 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 42/169 (24%), Positives = 72/169 (42%), Gaps = 22/169 (13%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 QS+ Q ++L+ D DG G + +L++ + +GL+L +DQ Sbjct: 51 QSNDYDLQQLKTVFLYLDEDGKGNITK-------NQLKKGLENSGLKLPQNFDVLLDQID 103 Query: 67 QRDDGKIGIVE-LAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 G+I E LA L + L C +R +D D+ G I T EL + Sbjct: 104 SDGSGRIDYTEFLAAALDRKHLSKKLIYC-----------AFRVFDVDNDGEITTAELAH 152 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 L + +K + T D + M++ D NNDGK++ E ++ ++ Sbjct: 153 ILYNGNKKGSITQKDVNQVKK---MIQEVDKNNDGKIDFYEFCEMMKLK 198 >5I0I-E nrPDB Length = 145 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F E + D DG G + KEL +++ L Q +A L+ +M VD G Sbjct: 9 AEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQ---DMINEVDADGN------ 59 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 G ++ L ++ + + S EE + +R +D D +G+I EL++ + +L EK Sbjct: 60 GTIDFPEFLT-----MMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 114 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M++ D + DG++ E +++ Sbjct: 115 LTD--------EEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 23/124 (18%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 61 Query: 162 LE----LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ LT MAR + + +E +AF ++D+DGNGYI EL ++ + Sbjct: 62 IDFPEFLTMMARKMKDTD-----------SEEEIREAFRVFDKDGNGYISAAELRHVMTN 110 Query: 218 LCEK 221 L EK Sbjct: 111 LGEK 114 >2LMV-A nrPDB Length = 148 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 33/120 (27%), Positives = 64/120 (53%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + ++D + +G I T EL ++ L + + AE DL+ + ++NN+G+ Sbjct: 11 EFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTE-------AELQDLIAEA-ENNNNGQ 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 L TE ++ Q ++ + +E +AF+++D+DG+G+I EL ++ +L EK Sbjct: 63 LNFTEFCGIMAKQ----MRETDTE---EEMREAFKIFDRDGDGFISPAELRFVMINLGEK 115 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 33/158 (20%), Positives = 72/158 (45%), Gaps = 22/158 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++F + ++ FD +G+G + +EL L++ L Q +A E++ + + ++G++ Sbjct: 10 AEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEA------ELQDLIAEAENNNNGQL 63 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E ++ + ++ + EE + ++ +D D GFI EL+ + +L EK Sbjct: 64 NFTEFCGIMAK--------QMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEK 115 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E D M++ D + DG + E ++ Sbjct: 116 VTD--------EEIDEMIREADFDGDGMINYEEFVWMI 145 >5E37-A nrPDB Length = 356 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 12/143 (8%) Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV 138 V+P F L EE + ++ D D +G I+ EEL+N L+ + + Sbjct: 7 VRVVPRAATFEGLMDDASKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMM 66 Query: 139 DDTKLAE-YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCG--KEFNKAF 195 L E + ++ +D N DG + E +++ + G+ + G E+ AF Sbjct: 67 SQHWLPEDELERCMEQYDVNKDGVISFEEFKQII---------YDGLLLEGTLAEYESAF 117 Query: 196 ELYDQDGNGYIDENELDALLKDL 218 + D+ GNG I EL L L Sbjct: 118 KAVDKSGNGTIGATELSKLFASL 140 Score = 37.0 bits (84), Expect = 0.009, Method: Compositional matrix adjust. Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 71/224 (31%) Query: 24 DADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLP 83 D DG+G+++ +EL+NL++ ++ G++ ++ H LP Sbjct: 39 DVDGNGHIDREELRNLLESMES-------------------------GEVYMMS-QHWLP 72 Query: 84 TEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD--LLEKANKTVDDT 141 +E L RC + +YD + G I EE K + D LLE Sbjct: 73 EDE----LERCME------------QYDVNKDGVISFEEFKQIIYDGLLLEGT------- 109 Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 LAEY + K D + +G + TE+++L N + ++ ++YD+D Sbjct: 110 -LAEY-ESAFKAVDKSGNGTIGATELSKLFASLGN--------PVSLEKLVDLMQMYDKD 159 Query: 202 GNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGG 245 +G I+ E + ++ LD+ ++TTY M L + G Sbjct: 160 DSGQIEFPEFLLMFRNSL------LDLKDMTTY----MTLDEAG 193 >3O4Y-A nrPDB Length = 196 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 22/155 (14%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE-L 78 +LH D +G G + +LQ L++ +++GL L P +DQ G I E L Sbjct: 61 FLHLDEEGKGNI--TKLQ-----LRKGLERSGLMLPPNFDLLLDQIDSDGSGNIDYTEFL 113 Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV 138 A + + L C +R +D D+ G I T EL + L + ++ N T Sbjct: 114 AAAIDRRQLSKKLIYC-----------AFRVFDVDNDGEITTAELAHVLFNGNKRGNITE 162 Query: 139 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 D + M++ D N DGK++ E + ++ + Sbjct: 163 RDVNQVKK---MIREVDKNGDGKIDFYEFSEMMKL 194 >1BJF-A nrPDB Length = 193 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 15/97 (15%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 SG + EE K + D +K AE+ + + FD+N DG ++ E L V Sbjct: 40 SGHLSMEEFKKIYGNFFPYG----DASKFAEH---VFRTFDANGDGTIDFREFIIALSVT 92 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 L+ ++ AF +YD DGNGYI + E+ Sbjct: 93 SRGKLE--------QKLKWAFSMYDLDGNGYISKAEM 121 Score = 31.6 bits (70), Expect = 0.38, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELT 165 YD D +G+I E+ ++ + + + + D++ + T+ + + D+N DGKL L Sbjct: 108 YDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLE 167 Query: 166 EMAR 169 E R Sbjct: 168 EFIR 171 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Query: 23 FDADGSGYLEGKELQNLIQEL----QQARKKAGLELSPEMKT--FVDQYGQRDDGKIGIV 76 +D DG+GY+ E+ ++Q + K E +PE +T Q DGK+ + Sbjct: 108 YDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLE 167 Query: 77 ELAHVLPTEENFLLLFRC 94 E ++ + + L +C Sbjct: 168 EFIRGAKSDPSIVRLLQC 185 >2L1W-A nrPDB Length = 149 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 37/156 (23%), Positives = 68/156 (43%), Gaps = 22/156 (14%) Query: 16 FFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGI 75 F E + FD DG G + +EL +I+ L Q +P + D + D G Sbjct: 12 FKEAFGLFDKDGDGCITVEELATVIRSLDQ---------NPTEEELQDMISEVDADGNGT 62 Query: 76 VELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKAN 135 +E L L+ + + + EE + ++ +D D +G+I EL++ + +L EK Sbjct: 63 IEFDEFLS-----LMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLT 117 Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E + M+K D + DG++ E +++ Sbjct: 118 D--------EEVEQMIKEADLDGDGQVNYEEFVKMM 145 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 +F + + +D D G I EEL ++ L D E M+ D++ +G Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSL--------DQNPTEEELQDMISEVDADGNGT 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E E L+ K +E +AF+++D+D NGYI +EL ++ +L EK Sbjct: 63 IEFDEFLSLMA-------KKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEK 115 >6EPA-A nrPDB Length = 187 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 8/72 (11%) Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD 199 D +++ L+ ++FD NNDG +E E R L + L ++ + AF LYD Sbjct: 58 DGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLD--------EKLHWAFRLYD 109 Query: 200 QDGNGYIDENEL 211 D +GYI E+ Sbjct: 110 VDNDGYITREEM 121 Score = 30.4 bits (67), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLE---KANKTVDDTKLAEYTDLMLKLFDSN 157 E+ +R YD D+ G+I EE+ N + + + + +T D+ + D + D N Sbjct: 99 EKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKN 158 Query: 158 NDGKLELTEM 167 +D +L L E Sbjct: 159 HDDRLTLEEF 168 >2LCP-A nrPDB Length = 190 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 11/73 (15%) Query: 139 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELY 198 D TK A + + +FD N DG++E +E + L V L ++ AF+LY Sbjct: 60 DPTKFATF---VFNVFDENKDGRIEFSEFIQALSVTSRGTLD--------EKLRWAFKLY 108 Query: 199 DQDGNGYIDENEL 211 D D +GYI NE+ Sbjct: 109 DLDNDGYITRNEM 121 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 14/113 (12%) Query: 60 TFV-DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 TFV + + + DG+I E L L E+ ++ YD D+ G+I Sbjct: 66 TFVFNVFDENKDGRIEFSEFIQALSVTSRGTL---------DEKLRWAFKLYDLDNDGYI 116 Query: 119 ETEELKNFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 E+ + + + + TV ++ + D + + D N DGKL L E Sbjct: 117 TRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEF 169 >2R2I-A nrPDB Length = 198 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 20/128 (15%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNF--LKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 S E + ++K+ T+ SG + E K F LK+L ANK Y + M + FD Sbjct: 12 SATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANK---------YVEQMFETFD 62 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 N DG ++ E L + +LK + ++ F+LYD DGNG ID EL ++ Sbjct: 63 FNKDGYIDFMEYVAALSL----VLKGK----VDQKLRWYFKLYDVDGNGCIDRGELLNII 114 Query: 216 KDLCEKNK 223 K + N+ Sbjct: 115 KAIRAINR 122 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 14/117 (11%) Query: 54 LSPEMKTFVDQ----YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRK 109 LSP +V+Q + DG I +E L L+L + K ++ ++ Sbjct: 46 LSPSANKYVEQMFETFDFNKDGYIDFMEYVAALS-----LVL----KGKVDQKLRWYFKL 96 Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 YD D +G I+ EL N +K + N+ + E+T+++ D N DG+L L E Sbjct: 97 YDVDGNGCIDRGELLNIIK-AIRAINRCNEAMTAEEFTNMVFDKIDINGDGELSLEE 152 >2LC5-A nrPDB Length = 151 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 22/131 (16%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 +E+ + ++ +D D+ + EEL ++ L AN T K++E ++K +D +N G Sbjct: 14 QEYKEAFQLFDKDNDNKLTAEELGTVMRAL--GANPT--KQKISE----IVKDYDKDNSG 65 Query: 161 KLELTEMARLLPVQENFL---LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 K + QE FL L++ ++ KAFE++D++ NGYI +EL +L Sbjct: 66 KFD----------QETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTT 115 Query: 218 LCEK-NKQDLD 227 L EK +Q++D Sbjct: 116 LGEKLTEQEVD 126 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 22/140 (15%) Query: 7 QSSLITA---SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVD 63 Q ++TA ++ E + FD D L +EL +++ L K ++ V Sbjct: 4 QKKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTK------QKISEIVK 57 Query: 64 QYGQRDDGKIGIVELAHVLPTEENFL--LLFRCQQLKSCEEFMKTWRKYDTDHSGFIETE 121 Y + + GK +E FL +L Q++ S E+ K + +D + +G+I Sbjct: 58 DYDKDNSGKFD----------QETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISAS 107 Query: 122 ELKNFLKDLLEK-ANKTVDD 140 ELK+ L L EK + VDD Sbjct: 108 ELKHVLTTLGEKLTEQEVDD 127 >3QRX-A nrPDB Length = 169 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 41/151 (27%), Positives = 71/151 (47%), Gaps = 26/151 (17%) Query: 23 FDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 82 FD DGSG ++ KEL+ ++ L KK E+K + + + G I Sbjct: 37 FDTDGSGTIDAKELKVAMRALGFEPKK------EEIKKMISEIDKDGSGTIDF------- 83 Query: 83 PTEENFLLLFRCQ--QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDD 140 E FL + + + S EE +K +R +D D+SG I ++L+ K+L E + + Sbjct: 84 ---EEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGE----NLTE 136 Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +L E M+ D N+D +++ E R++ Sbjct: 137 EELQE----MIAEADRNDDNEIDEDEFIRIM 163 Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust. Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 15/111 (13%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 +DTD SG I+ +ELK ++ L + K E M+ D + G ++ E Sbjct: 37 FDTDGSGTIDAKELKVAMRALGFEPKK--------EEIKKMISEIDKDGSGTIDFEEFLT 88 Query: 170 LLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ + G + +E KAF L+D D +G I +L + K+L E Sbjct: 89 MMTAK-------MGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGE 132 Score = 30.8 bits (68), Expect = 0.66, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 20/30 (66%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+L+D DG+G ID EL ++ L Sbjct: 28 QEIREAFDLFDTDGSGTIDAKELKVAMRAL 57 >5CPV-A nrPDB Length = 109 Score = 40.4 bits (93), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS ++ K + D D SGFIE +ELK FL++ A D T LK DS+ Sbjct: 39 KSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGE-----TKTFLKAGDSD 93 Query: 158 NDGKLELTEMARLLPV 173 DGK+ + E L+ Sbjct: 94 GDGKIGVDEFTALVKA 109 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 16/52 (30%) Query: 193 KAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 KAF + DQD +G+I+E+EL L++ +K + AL+DG Sbjct: 46 KAFAIIDQDKSGFIEEDELKLFLQN----------------FKADARALTDG 81 Score = 27.3 bits (59), Expect = 6.8, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 3/61 (4%) Query: 24 DADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLP 83 D D SG++E EL+ +Q + A E KTF+ DGKIG+ E ++ Sbjct: 52 DQDKSGFIEEDELKLFLQNF---KADARALTDGETKTFLKAGDSDGDGKIGVDEFTALVK 108 Query: 84 T 84 Sbjct: 109 A 109 >5T7C-A nrPDB Length = 193 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 15/97 (15%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 +G + +E K + D +K AE+ + + FD+N DG ++ E L V Sbjct: 40 TGHLTVDEFKKIYANFFPYG----DASKFAEH---VFRTFDTNGDGTIDFREFIIALSVT 92 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 L+ Q +K AF +YD DGNGYI +E+ Sbjct: 93 SRGKLE-QKLKW-------AFSMYDLDGNGYISRSEM 121 Score = 35.4 bits (80), Expect = 0.027, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 4/64 (6%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELT 165 YD D +G+I E+ ++ + + + + D++ + TD + + D+NNDGKL L Sbjct: 108 YDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLE 167 Query: 166 EMAR 169 E R Sbjct: 168 EFIR 171 Score = 30.4 bits (67), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 23 FDADGSGYLEGKELQNLIQEL----QQARKKAGLELSPEMKT--FVDQYGQRDDGKIGIV 76 +D DG+GY+ E+ ++Q + K E +PE +T Q +DGK+ + Sbjct: 108 YDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLE 167 Query: 77 ELAHVLPTEENFLLLFRC 94 E ++ + + L +C Sbjct: 168 EFIRGAKSDPSIVRLLQC 185 >2NLN-A nrPDB Length = 108 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 5/75 (6%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELS-PEMKTFVDQYGQ 67 S ++ASQ +I+ D D SGYL+G EL+ +Q+ Q + EL+ E K+ +D Sbjct: 36 SKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDAR----ELTESETKSLMDAADN 91 Query: 68 RDDGKIGIVELAHVL 82 DGKIG E ++ Sbjct: 92 DGDGKIGADEFQEMV 106 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S + +R D D SG+++ +ELK FL+ A + + T ++ D++ Sbjct: 39 SASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTE-----SETKSLMDAADNDG 93 Query: 159 DGKLELTEMARLL 171 DGK+ E ++ Sbjct: 94 DGKIGADEFQEMV 106 >3KF9-A nrPDB Length = 149 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 22/149 (14%) Query: 23 FDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 82 FD DGSG ++ KEL+ ++ L KK E+K + + G I E ++ Sbjct: 17 FDTDGSGTIDAKELKVAMRALGFEPKK------EEIKKMIADIDKDGSGTIDFEEFLQMM 70 Query: 83 PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTK 142 + + S EE MK +R +D D +G I + LK K+L E + D + Sbjct: 71 TA--------KMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGE----NMTDEE 118 Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLL 171 L E M+ D + DG++ E R++ Sbjct: 119 LQE----MIDEADRDGDGEVNEEEFFRIM 143 Score = 32.0 bits (71), Expect = 0.28, Method: Compositional matrix adjust. Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 15/111 (13%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 +DTD SG I+ +ELK ++ L + K E M+ D + G ++ E + Sbjct: 17 FDTDGSGTIDAKELKVAMRALGFEPKK--------EEIKKMIADIDKDGSGTIDFEEFLQ 68 Query: 170 LLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ + G + +E KAF L+D D G I L + K+L E Sbjct: 69 MMTAK-------MGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGE 112 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 20/30 (66%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+L+D DG+G ID EL ++ L Sbjct: 8 QEIREAFDLFDTDGSGTIDAKELKVAMRAL 37 >1BU3-A nrPDB Length = 109 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS ++ K + D D SGFIE +ELK FL+ A D AE T LK DS+ Sbjct: 39 KSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTD----AE-TKAFLKAGDSD 93 Query: 158 NDGKLELTEMARLL 171 DG + + E A L+ Sbjct: 94 GDGAIGVDEWAALV 107 >4DS7-A nrPDB Length = 147 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 60/120 (50%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D+SG I EL ++ L ++ AE DLM ++ D + + Sbjct: 12 EFKEAFALFDKDNSGSISASELATVMRSLGLSPSE-------AEVADLMNEI-DVDGNHA 63 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q LK + +E +AF+++D++G+G I EL +L + EK Sbjct: 64 IEFSEFLALMSRQ----LKCNDSE---QELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 116 >5ZGM-A nrPDB Length = 110 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 5/74 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS + + + D D SGFIE EELK+ LK + + DT+ T +L DS+ Sbjct: 39 KSEAQVKEVFEILDKDQSGFIEEEELKSVLKG-FSAHGRDLSDTE----TKALLAAGDSD 93 Query: 158 NDGKLELTEMARLL 171 +DGK+ E A+++ Sbjct: 94 HDGKIGADEFAKMV 107 Score = 30.4 bits (67), Expect = 0.82, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 11/83 (13%) Query: 181 FQGIKMCGK---EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKN 237 FQ + + GK + + FE+ D+D +G+I+E EL ++LK + D+++ T K Sbjct: 31 FQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGR---DLSDTET--KA 85 Query: 238 IMALSDG---GKLYRTDLALILC 257 ++A D GK+ + A ++ Sbjct: 86 LLAAGDSDHDGKIGADEFAKMVA 108 Score = 26.9 bits (58), Expect = 9.7, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELS-PEMKTFVDQYGQRDDGK 72 +Q E++ D D SG++E +EL+++++ G +LS E K + DGK Sbjct: 42 AQVKEVFEILDKDQSGFIEEEELKSVLKGFSA----HGRDLSDTETKALLAAGDSDHDGK 97 Query: 73 IGIVELAHVL 82 IG E A ++ Sbjct: 98 IGADEFAKMV 107 >2LHI-A nrPDB Length = 176 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 33/120 (27%), Positives = 62/120 (51%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D++G I + EL ++ L ++ AE DLM ++ D + + + Sbjct: 12 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSE-------AEVNDLMNEI-DVDGNHQ 63 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q LK + +E +AF+++D++G+G I EL +L + EK Sbjct: 64 IEFSEFLALMSRQ----LKSNDSE---QELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 116 >5M6C-E nrPDB Length = 193 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 15/97 (15%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 +G + +E K + D +K AE+ + + FD+N+DG ++ E L V Sbjct: 40 TGILNVDEFKKIYANFFPYG----DASKFAEH---VFRNFDTNSDGTIDFREFIIALSVT 92 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 L+ ++ AF +YD DGNGYI E+ Sbjct: 93 SRGRLE--------QKLMWAFSMYDLDGNGYISREEM 121 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDS 156 ++ M + YD D +G+I EE+ ++ + + + + D++ + T+ + + D+ Sbjct: 99 QKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDT 158 Query: 157 NNDGKLELTEMAR 169 NNDGKL L E R Sbjct: 159 NNDGKLSLEEFIR 171 Score = 30.8 bits (68), Expect = 0.68, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query: 23 FDADGSGYLEGKELQNLIQEL----QQARKKAGLELSPEMKT--FVDQYGQRDDGKIGIV 76 +D DG+GY+ +E+ ++Q + K E +PE +T Q +DGK+ + Sbjct: 108 YDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLE 167 Query: 77 ELAHVLPTEENFLLLFRC 94 E ++ + + L +C Sbjct: 168 EFIRGAKSDPSIVRLLQC 185 >5D43-A nrPDB Length = 178 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 71/150 (47%), Gaps = 24/150 (16%) Query: 23 FDADGSGYLEGKELQNLIQELQ-QARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHV 81 FD+DGSG ++ KEL+ ++ L + RK+ EMK + + + GKI + V Sbjct: 40 FDSDGSGTIDVKELKVAMRALGFEPRKE-------EMKKMISEVDKEATGKISFNDFLAV 92 Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 141 + + + + EE +K +R +D D +G I + LK +L E ++ D Sbjct: 93 MTQ--------KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE----SLTDE 140 Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +L E M+ D + DG++ E +++ Sbjct: 141 ELQE----MIDEADRDGDGEVNEEEFLKIM 166 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 20/30 (66%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+L+D DG+G ID EL ++ L Sbjct: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 >1LKJ-A nrPDB Length = 146 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 33/120 (27%), Positives = 62/120 (51%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D++G I + EL ++ L ++ AE DLM ++ D + + + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSE-------AEVNDLMNEI-DVDGNHQ 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q LK + +E +AF+++D++G+G I EL +L + EK Sbjct: 63 IEFSEFLALMSRQ----LKSNDSE---QELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 115 >4RGJ-A nrPDB Length = 520 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 14/132 (10%) Query: 90 LLFRCQQLKSCEE---FMKTWRKYDTDHSGFIETEELKNFLKDLLE-KANKTVD-DTKLA 144 LL+ +L + +E K ++K D + G ++ EL K+LL+ K T D D Sbjct: 357 LLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAI 416 Query: 145 EY-TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGN 203 EY D +L D + +G +E +E + + LL + KAF+L+D+DG+ Sbjct: 417 EYEVDQILNSIDLDQNGYIEYSEFLTV-SIDRKLLLSTE-------RLEKAFKLFDKDGS 468 Query: 204 GYIDENELDALL 215 G I NEL L Sbjct: 469 GKISANELAQLF 480 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 26/113 (23%) Query: 111 DTDHSGFIETEELKNFLKDLLEKANKTVD-DTKL---AEYTDLMLKLFDSNNDGKLELTE 166 D D +G+IE E FL TV D KL E + KLFD + GK+ E Sbjct: 428 DLDQNGYIEYSE---FL---------TVSIDRKLLLSTERLEKAFKLFDKDGSGKISANE 475 Query: 167 MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 +A+L + + + + + + DQ+ +G ID E +L LC Sbjct: 476 LAQLFGLSD----------VSSECWKTVLKEVDQNNDGEIDFKEFRDMLVKLC 518 >2I94-A nrPDB Length = 202 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 39/97 (40%), Gaps = 15/97 (15%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 SG I +E + +A+ Y + + FD+N+DG L+ E Sbjct: 41 SGRITRQEFQTIYSKFFPEADPKA-------YAQHVFRSFDANSDGTLDFKEYV------ 87 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 L ++ AF LYD DGNG I +NE+ Sbjct: 88 --IALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEV 122 >2D8N-A nrPDB Length = 207 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 14/79 (17%) Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNK-- 193 K DT Y + + FDSN DG L+ E L + GK K Sbjct: 62 KFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIAL-----------HMTTAGKTNQKLE 110 Query: 194 -AFELYDQDGNGYIDENEL 211 AF LYD DGNG I +NE+ Sbjct: 111 WAFSLYDVDGNGTISKNEV 129 >1S6I-A nrPDB Length = 188 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 27/155 (17%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLEL-SPEMKTFVDQYGQRDDGKIGIV 76 E++ D D SG + EL+ K+ G EL E+K +D D K G + Sbjct: 14 ELFKMIDTDNSGTI-------TFDELKDGLKRVGSELMESEIKDLMDAA---DIDKSGTI 63 Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 + + +L+ E + + +D D SG+I +E++ KD Sbjct: 64 DYGEFIAA------TVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDF------ 111 Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +DD + D M+K D +NDG+++ E A ++ Sbjct: 112 GLDDI----HIDDMIKEIDQDNDGQIDYGEFAAMM 142 Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 40/124 (32%) Query: 107 WRKYDTDHSGFIETEELKNFLK------------DLLEKANKTVDDTKLAEYTDLMLKLF 154 ++ DTD+SG I +ELK+ LK DL++ A+ +D + +Y + + Sbjct: 16 FKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAAD--IDKSGTIDYGEFIAATV 73 Query: 155 DSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 N L +EN + AF +D+DG+GYI +E+ Sbjct: 74 HLNK------------LEREENLV--------------SAFSYFDKDGSGYITLDEIQQA 107 Query: 215 LKDL 218 KD Sbjct: 108 CKDF 111 >2LHH-A nrPDB Length = 128 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 33/120 (27%), Positives = 61/120 (50%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D++G I + EL ++ L ++ AE DLM ++ D + + + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSE-------AEVNDLMNEI-DVDGNHQ 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q LK +E +AF+++D++G+G I EL +L + EK Sbjct: 63 IEFSEFLALMSRQ----LKSND---SEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 115 >5PAL-A nrPDB Length = 109 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 5/61 (8%) Query: 111 DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 D D SGFIE EELK LK + ++DT+ T +L DS++DGK+ E A++ Sbjct: 51 DKDQSGFIEEEELKGVLKG-FSAHGRDLNDTE----TKALLAAGDSDHDGKIGADEFAKM 105 Query: 171 L 171 + Sbjct: 106 V 106 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 8/71 (11%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG---GK 246 + + FE+ D+D +G+I+E EL +LK + D+N+ T K ++A D GK Sbjct: 42 QVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGR---DLNDTET--KALLAAGDSDHDGK 96 Query: 247 LYRTDLALILC 257 + + A ++ Sbjct: 97 IGADEFAKMVA 107 >3PAT-A nrPDB Length = 110 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S + K ++ D D SGFIE EELK LK D AE T LK D + Sbjct: 40 SANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTD----AE-TKAFLKAADKDG 94 Query: 159 DGKLELTEMARLL 171 DGK+ + E L+ Sbjct: 95 DGKIGIDEFETLV 107 Score = 32.3 bits (72), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 5/69 (7%) Query: 11 ITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELS-PEMKTFVDQYGQRD 69 ++A+ +++ DAD SG++E +EL+ +++ G +L+ E K F+ + Sbjct: 39 MSANDVKKVFKAIDADASGFIEEEELKFVLKSFAA----DGRDLTDAETKAFLKAADKDG 94 Query: 70 DGKIGIVEL 78 DGKIGI E Sbjct: 95 DGKIGIDEF 103 Score = 27.7 bits (60), Expect = 5.5, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 186 MCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 M + K F+ D D +G+I+E EL +LK Sbjct: 39 MSANDVKKVFKAIDADASGFIEEEELKFVLKSFA 72 >5ZH6-A nrPDB Length = 107 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 5/76 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS K + D D SGFIE +ELK FL++ A + +D+T+ T+ L DS+ Sbjct: 37 KSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATA-RELDETE----TNAFLAAGDSD 91 Query: 158 NDGKLELTEMARLLPV 173 +DGK+ + E ++ Sbjct: 92 HDGKIGVDEFKAMVKA 107 >1A75-A nrPDB Length = 108 Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 5/76 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS ++ K + D D SGFIE +ELK FL+ + + + + D + T LK DS+ Sbjct: 38 KSADDIKKAFVFIDQDKSGFIEEDELKLFLQ-VFKAGARALTDAE----TKAFLKAGDSD 92 Query: 158 NDGKLELTEMARLLPV 173 DG + + E L+ Sbjct: 93 GDGAIGVEEWVALVKA 108 >1JBA-A nrPDB Length = 204 Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 16/97 (16%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 SG + E K F K D+ + +Y + M + FD+N D ++ E L Sbjct: 37 SGTLFMHEFKRFFK--------VPDNEEATQYVEAMFRAFDTNGDNTIDFLEYVAAL--- 85 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 N +L+ + F++YD+D NG ID EL Sbjct: 86 -NLVLR----GTLEHKLKWTFKIYDKDRNGCIDRQEL 117 Score = 26.9 bits (58), Expect = 8.4, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 9/72 (12%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDL--LEKANKTVDDTK-------LAEYTDLMLKLFDS 156 T++ YD D +G I+ +EL + ++ + L+KA + + E D + L D Sbjct: 100 TFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDE 159 Query: 157 NNDGKLELTEMA 168 N DG+L L E Sbjct: 160 NGDGQLSLNEFV 171 >2OBH-A nrPDB Length = 143 Score = 36.6 bits (83), Expect = 0.010, Method: Compositional matrix adjust. Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 22/149 (14%) Query: 23 FDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 82 FDADG+G ++ KEL+ ++ L KK E+K + + + GK+ + V+ Sbjct: 15 FDADGTGTIDVKELKVAMRALGFEPKK------EEIKKMISEIDKEGTGKMNFGDFLTVM 68 Query: 83 PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTK 142 + + + EE +K ++ +D D +G I + LK K+L E + D + Sbjct: 69 TQ--------KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGE----NLTDEE 116 Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLL 171 L E M+ D + DG++ E R++ Sbjct: 117 LQE----MIDEADRDGDGEVSEQEFLRIM 141 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+L+D DG G ID EL ++ L Sbjct: 6 QEIREAFDLFDADGTGTIDVKELKVAMRAL 35 >2GGM-A nrPDB Length = 172 Score = 36.6 bits (83), Expect = 0.010, Method: Compositional matrix adjust. Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 22/149 (14%) Query: 23 FDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 82 FDADG+G ++ KEL+ ++ L KK E+K + + + GK+ + V+ Sbjct: 40 FDADGTGTIDVKELKVAMRALGFEPKKE------EIKKMISEIDKEGTGKMNFGDFLTVM 93 Query: 83 PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTK 142 + + + EE +K ++ +D D +G I + LK K+L E + D + Sbjct: 94 TQ--------KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGE----NLTDEE 141 Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLL 171 L E M+ D + DG++ E R++ Sbjct: 142 LQE----MIDEADRDGDGEVSEQEFLRIM 166 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+L+D DG G ID EL ++ L Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRAL 60 >2MBX-A nrPDB Length = 109 Score = 36.6 bits (83), Expect = 0.011, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS + K + D D S F+E +ELK FL++ A D AE T + LK DS+ Sbjct: 39 KSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSD----AE-TKVFLKAGDSD 93 Query: 158 NDGKLELTEMARLL 171 DGK+ + E ++ Sbjct: 94 GDGKIGVDEFGAMI 107 >2GGZ-A nrPDB Length = 211 Score = 36.2 bits (82), Expect = 0.017, Method: Compositional matrix adjust. Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 23/101 (22%) Query: 115 SGFIETEELKNFL--KDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM--ARL 170 SG E K L + L +KANK +D + FD+N DG ++ E A Sbjct: 34 SGLQTLHEFKTLLGLQGLNQKANKHIDQ---------VYNTFDTNKDGFVDFLEFIAAVN 84 Query: 171 LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 L +QE K + F+LYD DGNG ID+NEL Sbjct: 85 LIMQEKMEQKLKWY----------FKLYDADGNGSIDKNEL 115 >2LAP-A nrPDB Length = 167 Score = 35.8 bits (81), Expect = 0.017, Method: Compositional matrix adjust. Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 19/155 (12%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGL-ELSPEMKTFVDQYGQRDDGKIGIV 76 E + FD D GY+ ++L N ++ + + L ELS ++ + + DD V Sbjct: 29 EAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDD----FV 84 Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 EL P LL + +E +R++DT+ G I T EL+ ++ LL Sbjct: 85 ELMG--PK-----LLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVG 137 Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 D ++ DL N DG+++ E R++ Sbjct: 138 HRDIEEIIRDVDL-------NGDGRVDFEEFVRMM 165 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 32/140 (22%), Positives = 60/140 (42%), Gaps = 13/140 (9%) Query: 93 RCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLK 152 R + + EE + +R++D D G+I +L N ++ + + +L E + + Sbjct: 17 RSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTM----GYMPTEMELIELS----Q 68 Query: 153 LFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCG-KEFNKAFELYDQDGNGYIDENEL 211 + N G ++ + L+ + L + M G KE AF +D +G+G I +EL Sbjct: 69 QINMNLGGHVDFDDFVELMGPK----LLAETADMIGVKELRDAFREFDTNGDGEISTSEL 124 Query: 212 DALLKDLCEKNKQDLDINNI 231 ++ L DI I Sbjct: 125 REAMRKLLGHQVGHRDIEEI 144 >1Y1X-A nrPDB Length = 191 Score = 35.8 bits (81), Expect = 0.017, Method: Compositional matrix adjust. Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 22/122 (18%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 + + +E M+ +R DTD SG I EL L A LA T+ +L + Sbjct: 20 ARHMNDNQELMEWFRAVDTDGSGAISVPELNA----ALSSAGVPF---SLAT-TEKLLHM 71 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 +D N+ G++ E L +F+L + + F D G+G +D NE+ A Sbjct: 72 YDKNHSGEITFDEFKDL----HHFILSMR----------EGFRKRDSSGDGRLDSNEVRA 117 Query: 214 LL 215 L Sbjct: 118 AL 119 >1G33-A nrPDB Length = 73 Score = 35.8 bits (81), Expect = 0.018, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 +KS ++ K + D D SGFIE +EL + LK A A+ T ++ D Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLS-----AKETKTLMAAGDK 55 Query: 157 NNDGKLELTEMARLLP 172 + DGK+ + E + L+ Sbjct: 56 DGDGKIGVEEFSTLVA 71 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 5/54 (9%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 + K F + D+D +G+I+E+EL ++LK + +DL K +MA D Sbjct: 6 DVKKVFHILDKDKSGFIEEDELGSILKGFSS-DARDLSAKET----KTLMAAGD 54 >2NA0-A nrPDB Length = 205 Score = 35.8 bits (81), Expect = 0.018, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 25/129 (19%) Query: 98 KSCEEFMKT-----WRKYDTD-HSGFIETEELKNF--LKDLLEKANKTVDDTKLAEYTDL 149 KS EE T ++K+ T+ SG + E + F LK+L A ++Y + Sbjct: 8 KSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWA---------SQYVEQ 58 Query: 150 MLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDEN 209 M + FD N DG ++ E L + +LK + ++ F+LYD DGNG ID + Sbjct: 59 MFETFDFNKDGYIDFMEYEAAL----SLVLKGK----VEQKLRWYFKLYDVDGNGCIDRD 110 Query: 210 ELDALLKDL 218 EL +++ + Sbjct: 111 ELLTIIRAI 119 Score = 33.5 bits (75), Expect = 0.10, Method: Compositional matrix adjust. Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE-YTDLMLKLFDSNNDGKLELTE 166 YD D +G I+ +EL ++ + N D T AE +TD + D N DG+L L E Sbjct: 99 YDVDGNGCIDRDELLTIIR-AIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEE 155 >2RO9-A nrPDB Length = 69 Score = 35.4 bits (80), Expect = 0.022, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 8/73 (10%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S EE + +R +D D +GFI EL++ + +L EK E D M++ D + Sbjct: 2 SEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTD--------EEVDEMIREADVDG 53 Query: 159 DGKLELTEMARLL 171 DG++ E +++ Sbjct: 54 DGQINYEEFVKVM 66 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 22/33 (66%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +AF ++D+D NG+I EL ++ +L EK Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHVMTNLGEK 36 >5B8I-B nrPDB Length = 171 Score = 35.4 bits (80), Expect = 0.025, Method: Compositional matrix adjust. Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 36/148 (24%) Query: 101 EEFMKTWRKY---DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 EE + W+++ D D SG IE +E FL L + + T+ M+ +FD + Sbjct: 18 EEVDRLWKRFMKLDRDKSGTIERDE---FLS--LPQVSSNPLSTR-------MIAIFDED 65 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNK------AFELYDQDGNGYIDENEL 211 G ++ E G+ + NK AF++YD D +G+I EL Sbjct: 66 GGGDVDFQEFV-------------SGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGEL 112 Query: 212 DALLKDLCEKNKQDLDINNITTYKKNIM 239 +LK + N +D+ + I K IM Sbjct: 113 FIVLKMMVGSNLKDMQLQQIV--DKTIM 138 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 3/66 (4%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 165 ++ YD D GFI EL LK ++ + D +L + D + D + DG++ Sbjct: 95 AFKVYDIDRDGFISNGELFIVLKMMV---GSNLKDMQLQQIVDKTIMEADLDGDGRISFE 151 Query: 166 EMARLL 171 E R++ Sbjct: 152 EFTRMV 157 >1GGW-A nrPDB Length = 140 Score = 35.4 bits (80), Expect = 0.025, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 8/67 (11%) Query: 163 ELTEMARLLPVQ---ENFLL---KFQGIKMCG--KEFNKAFELYDQDGNGYIDENELDAL 214 E+TE+ LP + E FL + G M G +EF K F+++D+D G I EL + Sbjct: 42 EITEIESTLPAEVDMEQFLQVLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYV 101 Query: 215 LKDLCEK 221 L L EK Sbjct: 102 LTSLGEK 108 Score = 30.8 bits (68), Expect = 0.54, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 8/74 (10%) Query: 75 IVELAHVLPTE---ENFL-LLFRCQQL---KSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 I E+ LP E E FL +L R EEF+K ++ +D D +G I EL+ L Sbjct: 43 ITEIESTLPAEVDMEQFLQVLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVL 102 Query: 128 KDLLEK-ANKTVDD 140 L EK +N+ +D+ Sbjct: 103 TSLGEKLSNEEMDE 116 >3NCG-A nrPDB Length = 486 Score = 35.0 bits (79), Expect = 0.029, Method: Compositional matrix adjust. Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 29/137 (21%) Query: 90 LLFRCQQLKSCEE---FMKTWRKYDTDHSGFIETEEL----KNFLK-------DLLEKAN 135 LL+ +L + +E + +RK DT++ G ++ +EL F++ L++ Sbjct: 317 LLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEG 376 Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTE-MARLLPVQENFLLKFQGIKMCGKEFNKA 194 T++D D ++ L D + G +E +E +A + + I + + +A Sbjct: 377 STIEDQ-----IDSLMPLLDMDGSGSIEYSEFIASAID---------RTILLSRERMERA 422 Query: 195 FELYDQDGNGYIDENEL 211 F+++D+DG+G I EL Sbjct: 423 FKMFDKDGSGKISTKEL 439 Score = 28.1 bits (61), Expect = 3.8, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 9/67 (13%) Query: 23 FDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 82 FD DGSG + KEL L QA +E E+++ ++Q DG++ E +L Sbjct: 426 FDKDGSGKISTKELFKL---FSQADSSIQME---ELESIIEQVDNNKDGEVDFNEFVEML 479 Query: 83 PTEENFL 89 +NF+ Sbjct: 480 ---QNFV 483 Score = 27.3 bits (59), Expect = 7.6, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 11/82 (13%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 L S E + ++ +D D SG I T+EL L +A+ ++ E + +++ D+ Sbjct: 413 LLSRERMERAFKMFDKDGSGKISTKELFK----LFSQADSSIQ----MEELESIIEQVDN 464 Query: 157 NNDGKLELTEMARLLPVQENFL 178 N DG+++ E +L +NF+ Sbjct: 465 NKDGEVDFNEFVEML---QNFV 483 >2KQY-A nrPDB Length = 108 Score = 35.0 bits (79), Expect = 0.030, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 K+ ++ K + D D SGFIE EEL+ FLK+ A + T L D++ Sbjct: 38 KTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLT-----SAETKAFLAAGDTD 92 Query: 158 NDGKLELTEMARLL 171 DGK+ + E L+ Sbjct: 93 GDGKIGVEEFQSLV 106 Score = 30.8 bits (68), Expect = 0.55, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T Q +++ D D SG++E +ELQ ++ + + + S E K F+ DG Sbjct: 39 TPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSAR---VLTSAETKAFLAAGDTDGDG 95 Query: 72 KIGIVELAHVL 82 KIG+ E ++ Sbjct: 96 KIGVEEFQSLV 106 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 19/34 (55%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNK 223 + K F + DQD +G+I+E EL LK+ + Sbjct: 42 QIKKVFGILDQDKSGFIEEEELQLFLKNFSSSAR 75 >2KYF-A nrPDB Length = 108 Score = 35.0 bits (79), Expect = 0.032, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 5/74 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS + + +R D D SGFIE +ELK FL+ A A T L D + Sbjct: 38 KSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLT-----ASETKTFLAAADHD 92 Query: 158 NDGKLELTEMARLL 171 DGK+ E ++ Sbjct: 93 GDGKIGAEEFQEMV 106 Score = 35.0 bits (79), Expect = 0.033, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++SQ EI+ D D SG++E EL+ +Q + A + + E KTF+ DG Sbjct: 39 SSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESG---ARVLTASETKTFLAAADHDGDG 95 Query: 72 KIGIVELAHVL 82 KIG E ++ Sbjct: 96 KIGAEEFQEMV 106 >2BL0-C nrPDB Length = 142 Score = 34.7 bits (78), Expect = 0.037, Method: Compositional matrix adjust. Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 20/119 (16%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 EF + + +D++ +GFI E L+ LK V+ E M D+ + Sbjct: 5 VSEFKEAFELFDSERTGFITKEGLQTVLKQF----GVRVEPAAFNE----MFNEADATGN 56 Query: 160 GKLELTEMARLLPVQENFLLKFQGIKMCGKE--FNKAFELYDQDGNGYIDENEL-DALL 215 GK++ E ++ + +K E +AF +D +G GYI + L DALL Sbjct: 57 GKIQFPEFLSMMGRR---------MKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALL 106 Score = 30.4 bits (67), Expect = 0.71, Method: Compositional matrix adjust. Identities = 25/118 (21%), Positives = 56/118 (47%), Gaps = 14/118 (11%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 S+F E + FD++ +G++ + LQ ++ K+ G+ + P F + + + D Sbjct: 5 VSEFKEAFELFDSERTGFITKEGLQTVL-------KQFGVRVEP--AAFNEMFNEADATG 55 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 G ++ L ++ R +Q S + + +R +D + +G+I L++ L +L Sbjct: 56 NGKIQFPEFLS-----MMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNL 108 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDL 218 EF +AFEL+D + G+I + L +LK Sbjct: 7 EFKEAFELFDSERTGFITKEGLQTVLKQF 35 >1JC2-A nrPDB Length = 76 Score = 34.7 bits (78), Expect = 0.037, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 8/74 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS EE +R +D + GFI+ EEL L+ E + E + ++K D N Sbjct: 7 KSEEELANCFRIFDKNADGFIDIEELGEILRATGEHV--------IEEDIEDLMKDSDKN 58 Query: 158 NDGKLELTEMARLL 171 NDG+++ E +++ Sbjct: 59 NDGRIDFDEFLKMM 72 >1RTP-1 nrPDB Length = 109 Score = 34.7 bits (78), Expect = 0.038, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 5/75 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS ++ K + D D SGFIE +EL + LK A A+ T ++ D + Sbjct: 38 KSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLS-----AKETKTLMAAGDKD 92 Query: 158 NDGKLELTEMARLLP 172 DGK+ + E + L+ Sbjct: 93 GDGKIGVEEFSTLVA 107 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 5/59 (8%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 K + K F + D+D +G+I+E+EL ++LK + +DL K +MA D Sbjct: 37 KKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSS-DARDLSAKET----KTLMAAGD 90 >3KHE-A nrPDB Length = 191 Score = 34.7 bits (78), Expect = 0.044, Method: Compositional matrix adjust. Identities = 42/167 (25%), Positives = 74/167 (44%), Gaps = 18/167 (10%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLEL-SPEMKTFVDQYG 66 ++L + +I+ D +G G L+ KEL ++L Q + +L S +++ VD Sbjct: 34 TTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHIL 93 Query: 67 QRDD-GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 Q D + G +E + + + Q L S E + ++++D+D SG I EEL Sbjct: 94 QSVDFDRNGYIEYSEFVT------VCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGR 147 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 VDD E +L+ D NNDG+++ E ++ Sbjct: 148 LF------GVTEVDD----ETWHQVLQECDKNNDGEVDFEEFVEMMQ 184 Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust. Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 11/122 (9%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDD---TKLAEYTDLMLKL 153 L+ +E + +R+ D + G ++ +EL + L++ TV D +++ D +L+ Sbjct: 36 LEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQS 95 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 D + +G +E +E + ++ L + + AF+ +D DG+G I EL Sbjct: 96 VDFDRNGYIEYSEFVTVCMDKQLLLSR--------ERLLAAFQQFDSDGSGKITNEELGR 147 Query: 214 LL 215 L Sbjct: 148 LF 149 >1FW4-A nrPDB Length = 71 Score = 34.7 bits (78), Expect = 0.044, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 23/33 (69%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 6 EEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 38 Score = 33.5 bits (75), Expect = 0.092, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 8/76 (10%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S EE + +R +D D +G+I EL++ + +L EK E D M++ D + Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREADIDG 55 Query: 159 DGKLELTEMARLLPVQ 174 DG++ E +++ + Sbjct: 56 DGQVNYEEFVQMMTAK 71 >1V1G-A nrPDB Length = 222 Score = 34.7 bits (78), Expect = 0.045, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 31/61 (50%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 165 ++ YD +GFIE EELK + LL ++ + + + D D NDGK+++ Sbjct: 116 AFKLYDLRQTGFIEREELKEMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDID 175 Query: 166 E 166 E Sbjct: 176 E 176 Score = 31.2 bits (69), Expect = 0.52, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 7/70 (10%) Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 + D + +FD +G +E E R L V F ++ AF+LYD G+ Sbjct: 75 FADRIFDVFDVKRNGVIEFGEFVRSLGV-------FHPSAPVHEKVKFAFKLYDLRQTGF 127 Query: 206 IDENELDALL 215 I+ EL ++ Sbjct: 128 IEREELKEMV 137 >4PAL-A nrPDB Length = 108 Score = 34.7 bits (78), Expect = 0.046, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 5/74 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS ++ K + D D SGFIE +ELK FL++ A D AE T L D + Sbjct: 38 KSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTD----AE-TKAFLADGDKD 92 Query: 158 NDGKLELTEMARLL 171 DG + + E A ++ Sbjct: 93 GDGMIGVDEFAAMI 106 Score = 27.7 bits (60), Expect = 5.4, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 20/31 (64%) Query: 193 KAFELYDQDGNGYIDENELDALLKDLCEKNK 223 KAF + DQD +G+I+E+EL L++ + Sbjct: 45 KAFYVIDQDKSGFIEEDELKLFLQNFSPSAR 75 >3I5H-B nrPDB Length = 153 Score = 34.7 bits (78), Expect = 0.047, Method: Compositional matrix adjust. Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 31/127 (24%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + D D GFI E+LK+ L DD Sbjct: 13 RQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSL---GRVPPDD----------------- 52 Query: 158 NDGKLELTEMARLLPVQENF--LLKFQGIKMCGKE----FNKAFELYDQDGNGYIDENEL 211 EL M + P Q NF L G K+ G + AF ++D+DG G+I E+ L Sbjct: 53 -----ELNAMLKECPGQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYL 107 Query: 212 DALLKDL 218 LL+++ Sbjct: 108 KDLLENM 114 >4OKH-A nrPDB Length = 189 Score = 34.3 bits (77), Expect = 0.053, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 29/116 (25%) Query: 104 MKTWRK----YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL-FDSNN 158 +K W+K YDTD SG I + E++N + D N + D Y D + + FDS Sbjct: 84 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDS-- 141 Query: 159 DGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 F+ F +++ G +AF +D+DG+G I N L+ L Sbjct: 142 ------------------FICCF--VRLEG--MFRAFHAFDKDGDGIIKLNVLEWL 175 >3L19-A nrPDB Length = 214 Score = 34.3 bits (77), Expect = 0.056, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 76/156 (48%), Gaps = 21/156 (13%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQY-GQRDDGKIGIV 76 +I+ H D +G G L+ +EL + +L + A +L P++++ VD G D + G + Sbjct: 67 DIFRHIDKNGDGQLDRQELIDGYSKLS-GEEVAVFDL-PQIESEVDAILGAADFDRNGYI 124 Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN-FLKDLLEKAN 135 + + + + L +L+S ++K+D D +G I +EL + F D LE + Sbjct: 125 DYSEFVTVAMDRKSLLSKDKLESA------FQKFDQDGNGKISVDELASVFGLDHLE--S 176 Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 KT + M+ DSNNDG ++ E +++ Sbjct: 177 KTWKE---------MISGIDSNNDGDVDFEEFCKMI 203 Score = 33.9 bits (76), Expect = 0.073, Method: Compositional matrix adjust. Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 11/129 (8%) Query: 90 LLFRCQQLKSCEE---FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY 146 LL+ +L S EE +R D + G ++ +EL + L + D ++ Sbjct: 49 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE 108 Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 D +L D + +G ++ +E + +++ L K + AF+ +DQDGNG I Sbjct: 109 VDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSK--------DKLESAFQKFDQDGNGKI 160 Query: 207 DENELDALL 215 +EL ++ Sbjct: 161 SVDELASVF 169 >1RK9-A nrPDB Length = 110 Score = 34.3 bits (77), Expect = 0.057, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 5/75 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS ++ K + D D SGFIE +EL LK A A+ T +++ D + Sbjct: 39 KSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLS-----AKETKMLMAAGDKD 93 Query: 158 NDGKLELTEMARLLP 172 DGK+ + E + L+ Sbjct: 94 GDGKIGVDEFSTLVA 108 Score = 27.3 bits (59), Expect = 7.0, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 20/32 (62%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 K + K F + D+D +G+I+E+EL +LK Sbjct: 38 KKSADDVKKVFHMLDKDKSGFIEEDELGFILK 69 >2JNF-A nrPDB Length = 158 Score = 33.9 bits (76), Expect = 0.064, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 10/59 (16%) Query: 179 LKFQGIKMCGKEFN---------KAFELYDQDGNGYIDENELDALLKDLCEK-NKQDLD 227 K G + G+E N +AF LYD++GNGYI + + +L +L E + +DLD Sbjct: 72 FKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLD 130 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/71 (23%), Positives = 36/71 (50%), Gaps = 8/71 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 +E + +R YD + +G+I T+ ++ L +L D+T +E D M+ D++ G Sbjct: 91 QELREAFRLYDKEGNGYISTDVMREILAEL--------DETLSSEDLDAMIDEIDADGSG 142 Query: 161 KLELTEMARLL 171 ++ E ++ Sbjct: 143 TVDFEEFMGVM 153 >3HZT-A nrPDB Length = 467 Score = 33.9 bits (76), Expect = 0.069, Method: Compositional matrix adjust. Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 18/166 (10%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLEL-SPEMKTFVDQYG 66 ++L + +I+ D +G G L+ KEL ++L Q + +L S +++ VD Sbjct: 308 TTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHIL 367 Query: 67 QRDD-GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 Q D + G +E + E + Q L S E + ++++D+D SG I EEL Sbjct: 368 QSVDFDRNGYIEYS------EFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGR 421 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 VDD E +L+ D NNDG+++ E ++ Sbjct: 422 LF------GVTEVDD----ETWHQVLQECDKNNDGEVDFEEFVEMM 457 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 14/132 (10%) Query: 90 LLFRCQQLKSCEE---FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDD---TKL 143 +LF +L + EE + +R+ D + G ++ +EL + L++ TV D +++ Sbjct: 300 MLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQI 359 Query: 144 AEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGN 203 D +L+ D + +G +E +E + ++ L + + AF+ +D DG+ Sbjct: 360 EAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLSR--------ERLLAAFQQFDSDGS 411 Query: 204 GYIDENELDALL 215 G I EL L Sbjct: 412 GKITNEELGRLF 423 >5JOJ-A nrPDB Length = 97 Score = 33.9 bits (76), Expect = 0.075, Method: Compositional matrix adjust. Identities = 16/30 (53%), Positives = 18/30 (60%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLC 219 E +AF D DGNGYI NEL+ L K C Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC 42 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 16/95 (16%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 E + + K DTD +G+I E L DL + A + ++ E T+ ++ D + DG+ Sbjct: 13 ELREAFAKVDTDGNGYISFNE----LNDLFKAACLPLPGYRVREITENLMATGDLDQDGR 68 Query: 162 LELTEMARLLPVQENFLLKFQGIKM--CGKEFNKA 194 + E F+ F G+K K F KA Sbjct: 69 ISFDE----------FIKIFHGLKSTDVAKTFRKA 93 >3LIJ-A nrPDB Length = 494 Score = 33.9 bits (76), Expect = 0.082, Method: Compositional matrix adjust. Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 11/129 (8%) Query: 90 LLFRCQQLKSCEE---FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY 146 LL+ +L S EE +R D + G ++ +EL + L + D ++ Sbjct: 332 LLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESE 391 Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 D +L D + +G ++ +E + +++ L K + AF+ +DQDGNG I Sbjct: 392 VDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSK--------DKLESAFQKFDQDGNGKI 443 Query: 207 DENELDALL 215 +EL ++ Sbjct: 444 SVDELASVF 452 Score = 32.7 bits (73), Expect = 0.18, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 76/156 (48%), Gaps = 21/156 (13%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQY-GQRDDGKIGIV 76 +I+ H D +G G L+ +EL + +L + A +L P++++ VD G D + G + Sbjct: 350 DIFRHIDKNGDGQLDRQELIDGYSKLS-GEEVAVFDL-PQIESEVDAILGAADFDRNGYI 407 Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN-FLKDLLEKAN 135 + + + + L +L+S ++K+D D +G I +EL + F D LE + Sbjct: 408 DYSEFVTVAMDRKSLLSKDKLESA------FQKFDQDGNGKISVDELASVFGLDHLE--S 459 Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 KT + M+ DSNNDG ++ E +++ Sbjct: 460 KTWKE---------MISGIDSNNDGDVDFEEFCKMI 486 >5JOL-A nrPDB Length = 82 Score = 33.5 bits (75), Expect = 0.088, Method: Compositional matrix adjust. Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 4/54 (7%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 E +AF D DGNGYI NEL+ L K C L + +N+MA D Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC----LPLPGYRVREITENLMATGD 62 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 E + + K DTD +G+I E L DL + A + ++ E T+ ++ D + DG+ Sbjct: 13 ELREAFAKVDTDGNGYISFNE----LNDLFKAACLPLPGYRVREITENLMATGDLDQDGR 68 Query: 162 LELTEMARLL 171 + E ++ Sbjct: 69 ISFDEFIKIF 78 >2K2A-A nrPDB Length = 70 Score = 33.5 bits (75), Expect = 0.099, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK-NKQDLD 227 +E +AF LYD++GNGYI + + +L +L E + +DLD Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLD 42 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 8/72 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 +E + +R YD + +G+I T+ ++ L +L D+T +E D M+ D++ G Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAEL--------DETLSSEDLDAMIDEIDADGSG 54 Query: 161 KLELTEMARLLP 172 ++ E ++ Sbjct: 55 TVDFEEFMGVMT 66 >2I08-A nrPDB Length = 78 Score = 33.5 bits (75), Expect = 0.099, Method: Compositional matrix adjust. Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 5/46 (10%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDL----CEKNKQDLDINNI 231 EF +AF LYD+DG+G I EL +++ L E QD+ IN + Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDM-INEV 55 >1DTL-A nrPDB Length = 161 Score = 33.5 bits (75), Expect = 0.10, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 73/159 (45%), Gaps = 29/159 (18%) Query: 17 FEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIV 76 F+I++ DGS + KEL +++ L Q L+ EM VD+ G G V Sbjct: 24 FDIFVLGAEDGS--ISTKELGKVMRMLGQNPTPEELQ---EMIDEVDEDGS------GTV 72 Query: 77 ELAHVLPTEENFLLLFRC----QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + L +++ R + KS EE +R +D + G+I+ EELK +L+ Sbjct: 73 DFDEFL------VMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKI----MLQ 122 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +T+ + + E ++K D NNDG+++ E + Sbjct: 123 ATGETITEDDIEE----LMKDGDKNNDGRIDYDEFLEFM 157 >5COC-A nrPDB Length = 130 Score = 33.5 bits (75), Expect = 0.10, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 21/32 (65%) Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLKDL 218 C EF +AF L+D+DG+G I EL +++ L Sbjct: 61 CIAEFKEAFSLFDKDGDGTITTKELGTVMRSL 92 Score = 26.9 bits (58), Expect = 8.9, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLE 53 ++F E + FD DG G + KEL +++ L Q +A L+ Sbjct: 63 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ 102 >4ORC-B nrPDB Length = 170 Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust. Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 20/140 (14%) Query: 105 KTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 164 K ++K D D+SG + EE ++ + + ++ +FD++ +G+++ Sbjct: 25 KRFKKLDLDNSGSLSVEEFM------------SLPELQQNPLVQRVIDIFDTDGNGEVDF 72 Query: 165 TEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQ 224 E + F +K G K F AF +YD D +GYI EL +LK + N + Sbjct: 73 KEFIEGVS---QFSVK--GDKEQKLRF--AFRIYDMDKDGYISNGELFQVLKMMVGNNLK 125 Query: 225 DLDINNITTYKKNIMALSDG 244 D + I K I A DG Sbjct: 126 DTQLQQIVD-KTIINADKDG 144 Score = 31.2 bits (69), Expect = 0.44, Method: Compositional matrix adjust. Identities = 41/174 (23%), Positives = 69/174 (39%), Gaps = 36/174 (20%) Query: 13 ASQFFEIWLHFDAD---------------GSGYLEGKELQNLIQELQQARKKAGLELSPE 57 AS E+ HFDAD SG L +E +L ELQQ +P Sbjct: 5 ASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSL-PELQQ---------NPL 54 Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGF 117 ++ +D + +G++ E + F + K ++ +R YD D G+ Sbjct: 55 VQRVIDIFDTDGNGEVDFKEFIEGVSQ-------FSVKGDKE-QKLRFAFRIYDMDKDGY 106 Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 I EL LK ++ + DT+L + D + D + DG++ E ++ Sbjct: 107 ISNGELFQVLKMMV---GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 >5ZOR-A nrPDB Length = 149 Score = 33.1 bits (74), Expect = 0.13, Method: Compositional matrix adjust. Identities = 42/165 (25%), Positives = 65/165 (39%), Gaps = 25/165 (15%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSP--EMKTFVDQYG 66 + +T Q E + FDADGSG ++ +E+ A K G P E++ V Sbjct: 2 AALTDEQIREAFNLFDADGSGAIDA-------EEMALAMKGLGFGDLPRDEVERTVRSMN 54 Query: 67 QRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 126 +G I E ++ + R Q S EE +K ++ +D D G I LK Sbjct: 55 TNANGLIEYGEFERMVKS--------RMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEV 106 Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 K L E V +AE D + DG++ E ++ Sbjct: 107 AKLLGENPGDDVLQEMIAEA--------DEDGDGEVSFEEFKSVM 143 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 14/126 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E+ + + +D D SG I+ EE+ +K L D E + ++ ++N +G Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGL------GFGDLPRDE-VERTVRSMNTNANG 59 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 +E E R++ + K +E KAF+L+D D G I L + K L E Sbjct: 60 LIEYGEFERMVKSR-------MAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGE 112 Query: 221 KNKQDL 226 D+ Sbjct: 113 NPGDDV 118 >2ZFD-A nrPDB Length = 226 Score = 33.1 bits (74), Expect = 0.13, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 1/75 (1%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 165 +++ YD GFIE +E+K + L ++ + DT + + D + D+ +DGK++ Sbjct: 127 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 186 Query: 166 EMARLLPVQENFLLK 180 E R L ++ LLK Sbjct: 187 EW-RSLVLRHPSLLK 200 Score = 31.6 bits (70), Expect = 0.33, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 7/70 (10%) Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 + D + LFD+ ++G L E AR L V F + + +F+LYD G+ Sbjct: 86 FADRVFDLFDTKHNGILGFEEFARALSV-------FHPNAPIDDKIHFSFQLYDLKQQGF 138 Query: 206 IDENELDALL 215 I+ E+ ++ Sbjct: 139 IERQEVKQMV 148 >2LV7-A nrPDB Length = 100 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 22/30 (73%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+++D+DGNG+I + EL ++ L Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSL 65 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 17/72 (23%), Positives = 35/72 (48%), Gaps = 8/72 (11%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 EE + ++ +D D +GFI +EL ++ L N+ +++++ D + D Sbjct: 35 LEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEV--------ELEVIIQRLDMDGD 86 Query: 160 GKLELTEMARLL 171 G+++ E LL Sbjct: 87 GQVDFEEFVTLL 98 >3I5I-C nrPDB Length = 159 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Query: 170 LLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDIN 229 +LP+ E K G EF +AF+ +D++G G I E+ +LK L E+ +D N Sbjct: 68 ILPIYEEMSSKDTGT--AADEFMEAFKTFDREGQGLISSAEIRNVLKMLGERITED-QCN 124 Query: 230 NITTY 234 +I T+ Sbjct: 125 DIFTF 129 >5MKE-A nrPDB Length = 968 Score = 32.7 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINN 230 E F YDQDG+ + E+E + DL EK ++DLD+++ Sbjct: 754 EIEAIFTKYDQDGDQELTEHEHQQMRDDL-EKEREDLDLDH 793 >5OTJ-D nrPDB Length = 110 Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 16/92 (17%) Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDG 202 +A+ + + K FD+N DGK+ L+E+ L + E + D DG Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALRTLGS---------TSADEVQRMMAEIDTDG 51 Query: 203 NGYIDENEL-------DALLKDLCEKNKQDLD 227 +G+ID NE L+KD+ + K +L+ Sbjct: 52 DGFIDFNEFISFCNANPGLMKDVAKVFKGELN 83 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 10/73 (13%) Query: 54 LSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTD 113 ++ +M+ ++ DGKI + EL L R S +E + + DTD Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDAL----------RTLGSTSADEVQRMMAEIDTD 50 Query: 114 HSGFIETEELKNF 126 GFI+ E +F Sbjct: 51 GDGFIDFNEFISF 63 >2KZ2-A nrPDB Length = 94 Score = 32.3 bits (72), Expect = 0.19, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 22/33 (66%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +AF + D+DGNGYI EL ++ +L EK Sbjct: 29 EEIREAFRVEDKDGNGYISAAELRHVMTNLGEK 61 Score = 31.6 bits (70), Expect = 0.40, Method: Compositional matrix adjust. Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 8/89 (8%) Query: 86 ENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE 145 EN + S EE + +R D D +G+I EL++ + +L EK E Sbjct: 14 ENLYFQSLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTD--------E 65 Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 D M++ D + DG++ E +++ + Sbjct: 66 EVDEMIREADIDGDGQVNYEEFVQMMTAK 94 >1YX7-A nrPDB Length = 83 Score = 32.3 bits (72), Expect = 0.21, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 E ++K D + G++ EL+ F+ L A K + K+ E + ++K+ D N+DGK Sbjct: 8 ELEAAFKKLDANGDGYVTALELQTFMVTL--DAYKALSKDKVKEASAKLIKMADKNSDGK 65 Query: 162 L 162 + Sbjct: 66 I 66 >2NCO-A nrPDB Length = 102 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Query: 105 KTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 164 + +++YD D SG ++ +E+ LKD + + + T E + L++ D+N+DG + L Sbjct: 19 RLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMS-NFTPTKEDVKIWLQMADTNSDGSVSL 77 Query: 165 TEMARLL 171 E L+ Sbjct: 78 EEYEDLI 84 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 29/47 (61%), Gaps = 4/47 (8%) Query: 192 NKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNI 238 + F+ YD+DG+G + ++E+ LLKD ++ ++N T K+++ Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTY----AEMGMSNFTPTKEDV 60 >1OZS-A nrPDB Length = 73 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 8/74 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS EE +R +D + G+I+ EELK +L+ +T+ + + E ++K D N Sbjct: 4 KSEEELSDLFRMFDKNADGYIDLEELKI----MLQATGETITEDDIEE----LMKDGDKN 55 Query: 158 NDGKLELTEMARLL 171 NDG+++ E + Sbjct: 56 NDGRIDYDEFLEFM 69 >1F55-A nrPDB Length = 77 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 20/29 (68%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDL 218 EF +AF L+D+D NG I +EL +++ L Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSL 39 Score = 27.7 bits (60), Expect = 5.7, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 36/75 (48%), Gaps = 9/75 (12%) Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 ++AE+ + LFD +N+G + +E+A +++ G+ E N D D Sbjct: 8 QIAEFKE-AFALFDKDNNGSISSSELAT--------VMRSLGLSPSEAEVNDLMNEIDVD 58 Query: 202 GNGYIDENELDALLK 216 GN I+ +E AL+ Sbjct: 59 GNHQIEFSEFLALMS 73 >2HF5-A nrPDB Length = 68 Score = 32.0 bits (71), Expect = 0.25, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 21/30 (70%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF ++D+DGNGYI EL ++ +L Sbjct: 38 EEIREAFRVFDKDGNGYISAAELRHVMTNL 67 >2KN2-A nrPDB Length = 92 Score = 32.0 bits (71), Expect = 0.25, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 24/33 (72%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +AF+++D+D NGYI +EL ++ +L EK Sbjct: 9 EELKEAFKVFDKDQNGYISASELRHVMINLGEK 41 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 8/71 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EE + ++ +D D +G+I EL++ + +L EK E + M+K D + DG Sbjct: 9 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEADLDGDG 60 Query: 161 KLELTEMARLL 171 ++ E +++ Sbjct: 61 QVNYEEFVKMM 71 >3AAJ-A nrPDB Length = 167 Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust. Identities = 26/109 (23%), Positives = 41/109 (37%), Gaps = 21/109 (19%) Query: 108 RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 ++ D D SG I EL+ L + V + + +FD N + +E Sbjct: 11 QRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSI-------ISMFDRENKAGVNFSE- 62 Query: 168 ARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 F G+ ++ F YD+D +G ID+NEL L Sbjct: 63 -------------FTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALS 98 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 26/110 (23%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLA-EYTDLMLKLFDS 156 K ++ +R YD D+SG I+ ELK L +L+ ++ D++++ FD Sbjct: 68 KYITDWQNVFRTYDRDNSGMIDKNELKQALSGY-----------RLSDQFHDILIRKFDR 116 Query: 157 NNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 G++ + +Q +L + F YD D +G+I Sbjct: 117 QGRGQIAFDDF-----IQGCIVL---------QRLTDIFRRYDTDQDGWI 152 >1UHN-A nrPDB Length = 189 Score = 32.0 bits (71), Expect = 0.26, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 7/70 (10%) Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 + D + LFD+ ++G L E AR L V F + + +F+LYD G+ Sbjct: 55 FADRVFDLFDTKHNGILGFEEFARALSV-------FHPNAPIDDKIHFSFQLYDLKQQGF 107 Query: 206 IDENELDALL 215 I+ E+ ++ Sbjct: 108 IERQEVKQMV 117 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 35/66 (53%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 165 +++ YD GFIE +E+K + L ++ + DT + + D + D+ +DGK++ Sbjct: 96 SFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKE 155 Query: 166 EMARLL 171 E L+ Sbjct: 156 EWRSLV 161 >2M5E-A nrPDB Length = 73 Score = 32.0 bits (71), Expect = 0.27, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 8/73 (10%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S EE ++ ++ +D D +G I EL++ + +L E K DD D M++ D + Sbjct: 6 SEEELIEAFKVFDRDGNGLISAAELRHVMTNLGE---KLTDDE-----VDEMIREADIDG 57 Query: 159 DGKLELTEMARLL 171 DG + E R++ Sbjct: 58 DGHINYEEFVRMM 70 Score = 30.4 bits (67), Expect = 0.76, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 23/33 (69%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +AF+++D+DGNG I EL ++ +L EK Sbjct: 8 EELIEAFKVFDRDGNGLISAAELRHVMTNLGEK 40 >4Q57-A nrPDB Length = 65 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 22/35 (62%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQ 224 EF +AF L+D+DG+G I EL +++ L + + Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE 37 Score = 27.3 bits (59), Expect = 7.1, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLE 53 ++F E + FD DG G + KEL +++ L Q +A L+ Sbjct: 2 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ 41 >3IFK-A nrPDB Length = 90 Score = 32.0 bits (71), Expect = 0.31, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 5/46 (10%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDL----CEKNKQDLDINNI 231 EF +AF L+D+DG+G I EL +++ L E QD+ IN + Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM-INEV 55 Score = 26.9 bits (58), Expect = 8.9, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLE 53 ++F E + FD DG G + KEL +++ L Q +A L+ Sbjct: 10 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ 49 >2AMI-A nrPDB Length = 96 Score = 31.6 bits (70), Expect = 0.32, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 20/30 (66%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+L+D DG+G ID EL ++ L Sbjct: 30 QEIREAFDLFDTDGSGTIDAKELKVAMRAL 59 >5JN2-A nrPDB Length = 525 Score = 31.6 bits (70), Expect = 0.35, Method: Compositional matrix adjust. Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 18/109 (16%) Query: 111 DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 D D +G+IE E D KT+ E + ++FDS+N GK+ TE+A + Sbjct: 433 DFDKNGYIEYSEFVTVAMD-----RKTLLSR---ERLERAFRMFDSDNSGKISSTELATI 484 Query: 171 LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 V + + + + D++ +G +D +E +L LC Sbjct: 485 FGVSD----------VDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLC 523 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 22/92 (23%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 L S E + +R +D+D+SG I + EL V D +E +L D Sbjct: 455 LLSRERLERAFRMFDSDNSGKISSTELATIF---------GVSDVD-SETWKSVLSEVDK 504 Query: 157 NNDGKLELTEMARLLPVQENFLLKFQGIKMCG 188 NNDG+++ E ++L +K+CG Sbjct: 505 NNDGEVDFDEFQQML------------LKLCG 524 >2LVK-A nrPDB Length = 77 Score = 31.6 bits (70), Expect = 0.38, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 9/62 (14%) Query: 150 MLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDEN 209 + K FD+N DGK+ L+E+ L + E + D DG+G+ID N Sbjct: 7 IFKRFDTNGDGKISLSELTDALRTLGS---------TSADEVQRMMAEIDTDGDGFIDFN 57 Query: 210 EL 211 E Sbjct: 58 EF 59 Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 10/70 (14%) Query: 57 EMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116 +M+ ++ DGKI + EL L R S +E + + DTD G Sbjct: 3 DMERIFKRFDTNGDGKISLSELTDAL----------RTLGSTSADEVQRMMAEIDTDGDG 52 Query: 117 FIETEELKNF 126 FI+ E +F Sbjct: 53 FIDFNEFISF 62 >2ROB-A nrPDB Length = 70 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 24/33 (72%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +AF+++D+D NGYI +EL ++ +L EK Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVMINLGEK 36 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 8/71 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EE + ++ +D D +G+I EL++ + +L EK E + M+K D + DG Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEADLDGDG 55 Query: 161 KLELTEMARLL 171 ++ E +++ Sbjct: 56 QVNYEEFVKMM 66 >3Q5I-A nrPDB Length = 504 Score = 31.2 bits (69), Expect = 0.46, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 145 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 E TD+ KL D N DG+L+ E+ V NF + +K +E + + D D NG Sbjct: 356 ELTDIFKKL-DKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDFDKNG 414 Query: 205 YIDENELDALLKD 217 YI+ +E ++ D Sbjct: 415 YIEYSEFISVCMD 427 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 38/159 (23%), Positives = 70/159 (44%), Gaps = 18/159 (11%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 ++L + +I+ D +G G L+ KEL L+ + + G EL + + + Sbjct: 349 TTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELG-ELKNVEEEVDNILKE 407 Query: 68 RDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 D K G +E + + + +LF ++L+ + + +DTD SG I EEL N Sbjct: 408 VDFDKNGYIEYSEFISVCMDKQILFSEERLR------RAFNLFDTDKSGKITKEELANLF 461 Query: 128 ----------KDLLEKANKTVDD-TKLAEYTDLMLKLFD 155 D+L +A++ D+ E+ +M K+ D Sbjct: 462 GLTSISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKICD 500 >5YPX-A nrPDB Length = 223 Score = 31.2 bits (69), Expect = 0.49, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 12/93 (12%) Query: 124 KNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQG 183 +N +D+L + +D + D + + FD ++D + LTE L V FL Sbjct: 64 RNLFRDILHQKFNMTEDLLM----DRVFRAFDKDSDSYISLTEWVEGLSV---FLRGTLD 116 Query: 184 IKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 KM F ++D +G+GYI E+ +LK Sbjct: 117 EKM-----EYTFTVFDLNGDGYISREEMFQMLK 144 >2RO8-A nrPDB Length = 79 Score = 30.8 bits (68), Expect = 0.54, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 20/29 (68%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDL 218 EF +AF L+D+DG+G I EL +++ L Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSL 39 Score = 28.1 bits (61), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 23/40 (57%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLE 53 S+F E + FD DG G + KEL +++ L Q +A L+ Sbjct: 10 SEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQ 49 >3DTP-E nrPDB Length = 196 Score = 30.8 bits (68), Expect = 0.56, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 28/42 (66%), Gaps = 5/42 (11%) Query: 189 KEFNKAFELYDQDGNGYIDENELDAL---LKDLCEKNKQDLD 227 +EF +AF+L DQD +G+I +N++ A L LC +Q+LD Sbjct: 57 QEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLC--TEQELD 96 >1ZMZ-A nrPDB Length = 98 Score = 30.8 bits (68), Expect = 0.59, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDL 218 +E +AF+L+D DG G ID EL ++ L Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRAL 60 >5H7D-E nrPDB Length = 120 Score = 30.8 bits (68), Expect = 0.68, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 21/32 (65%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + F +AF L+D+DG+G I EL +++ L + Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 87 Score = 28.1 bits (61), Expect = 3.8, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 12/84 (14%) Query: 90 LLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDL 149 LL ++L + F + + +D D G I T+EL ++ L + + AE D Sbjct: 45 LLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD- 96 Query: 150 MLKLFDSNNDGKLE----LTEMAR 169 M+ D++ +G ++ LT MAR Sbjct: 97 MINEVDADGNGTIDFPEFLTMMAR 120 >3FWC-A nrPDB Length = 161 Score = 30.4 bits (67), Expect = 0.71, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 8/67 (11%) Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 +LFD ++ GK+ + + R+ K G + +E E +D DG+G I+ENE Sbjct: 102 FQLFDDDHTGKISIKNLRRVA--------KELGETLTDEELRAMIEEFDLDGDGEINENE 153 Query: 211 LDALLKD 217 A+ D Sbjct: 154 FIAICTD 160 >1TRF-A nrPDB Length = 76 Score = 30.4 bits (67), Expect = 0.77, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCE-KNKQDLD 227 EF AF+++D DG G I EL +++ L + K++LD Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELD 48 >1SR6-C nrPDB Length = 156 Score = 30.4 bits (67), Expect = 0.80, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 6/65 (9%) Query: 171 LPVQENFLLKFQGIKMCGK----EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDL 226 LP +E FL ++G+ C + ++ +AF+ +D++G G+I EL +L L E+ D Sbjct: 63 LPFEE-FLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGER-LSDE 120 Query: 227 DINNI 231 D++ I Sbjct: 121 DVDEI 125 Score = 27.7 bits (60), Expect = 5.9, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 11/74 (14%) Query: 82 LPTEENFLLLFRCQQLKSCEE-----FMKTWRKYDTDHSGFIETEELKNFLKDLLEK-AN 135 LP EE FL + + L CE+ +M+ ++ +D + GFI EL++ L L E+ ++ Sbjct: 63 LPFEE-FLPAY--EGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLSD 119 Query: 136 KTVDDTKLAEYTDL 149 + VD ++ + TDL Sbjct: 120 EDVD--EIIKLTDL 131 >3DD4-A nrPDB Length = 229 Score = 30.4 bits (67), Expect = 0.85, Method: Compositional matrix adjust. Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 15/104 (14%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 SG + E K + + T Y + FD++++G + + + L + Sbjct: 79 SGVVNEETFKEIYSQFFPQGDSTT-------YAHFLFNAFDTDHNGAVSFEDFIKGLSI- 130 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL 218 LL+ ++ N AF LYD + +GYI + E+ ++K + Sbjct: 131 ---LLR----GTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAI 167 >1TNP-A nrPDB Length = 90 Score = 30.4 bits (67), Expect = 0.89, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCE-KNKQDLD 227 EF AF+++D DG G I EL +++ L + K++LD Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELD 59 >2K7C-A nrPDB Length = 72 Score = 30.0 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 7/71 (9%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 +E +R++DT+ G I T EL+ ++ LL D ++ DL N DG Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDL-------NGDG 59 Query: 161 KLELTEMARLL 171 +++ E R++ Sbjct: 60 RVDFEEFVRMM 70 >1OQP-A nrPDB Length = 77 Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 40/73 (54%), Gaps = 8/73 (10%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S EE +K +R +D D+SG I ++L+ K+L E + + +L E M+ D N+ Sbjct: 7 SREEILKAFRLFDDDNSGTITIKDLRRVAKELGE----NLTEEELQE----MIAEADRND 58 Query: 159 DGKLELTEMARLL 171 D +++ E R++ Sbjct: 59 DNEIDEDEFIRIM 71 >2JU0-A nrPDB Length = 190 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 20/110 (18%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 +D D++GFI EE L T L E +L+D N+DG + EM Sbjct: 72 FDKDNNGFIHFEEFITVLS--------TTSRGTLEEKLSWAFELYDLNHDGYITFDEMLT 123 Query: 170 LLPVQENFLLKFQGIKMCGKE--------FNKAFELYDQDGNGYIDENEL 211 ++ + K G + E K F+L D++ +GYI +E Sbjct: 124 IVAS----VYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 8/67 (11%) Query: 145 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 ++ + + +FD +N+G + E +L L+ ++ + AFELYD + +G Sbjct: 63 DFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLE--------EKLSWAFELYDLNHDG 114 Query: 205 YIDENEL 211 YI +E+ Sbjct: 115 YITFDEM 121 >1C7W-A nrPDB Length = 81 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 9/67 (13%) Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIK-MCGKEFNKAFELYDQDGNGYIDEN 209 K+FD+N DG ++ E F+++ G + + E +A + D+DGNG ID Sbjct: 14 FKVFDANGDGVIDFDEF--------KFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIP 65 Query: 210 ELDALLK 216 E L+K Sbjct: 66 EFMDLIK 72 >2M97-A nrPDB Length = 69 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 10/28 (35%), Positives = 20/28 (71%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLK 216 +E ++ F ++D+DGNG+ID E +++ Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIR 30 >2B1U-A nrPDB Length = 71 Score = 29.6 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E+ +R +D D G I +EL+ + L + + E D M++ D + DG Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQ--------EELDAMIREADVDQDG 57 Query: 161 KLELTEMARLL 171 ++ E AR+L Sbjct: 58 RVNYEEFARML 68 >2AAO-A nrPDB Length = 166 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 26/106 (24%) Query: 111 DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE-MAR 169 D D SG I EELK LK + + K +E DLM + D +N G ++ E +A Sbjct: 37 DADKSGQITFEELKAGLK-------RVGANLKESEILDLM-QAADVDNSGTIDYKEFIAA 88 Query: 170 LLPV----QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 L + +E+ L AF +D+DG+GYI +EL Sbjct: 89 TLHLNKIEREDHLFA-------------AFTYFDKDGSGYITPDEL 121 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQEL 43 F + +FD DGSGY+ ELQ +E Sbjct: 100 HLFAAFTYFDKDGSGYITPDELQQACEEF 128 >5MWC-D nrPDB Length = 311 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 13/58 (22%), Positives = 27/58 (46%), Gaps = 14/58 (24%) Query: 159 DGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 DG + + ++P +E E ++ F +D+DG+G+ID E +++ Sbjct: 135 DGPVMANSLTAMVPSEE--------------ELSECFRTFDKDGDGFIDREEFGGIIR 178 >5TBY-E nrPDB Length = 166 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 27/43 (62%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNI 231 +EF +AF + DQ+ +G+ID+N+L L N ++ +I+ + Sbjct: 27 QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEM 69 >3AKA-A nrPDB Length = 166 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 15/24 (62%) Query: 195 FELYDQDGNGYIDENELDALLKDL 218 F +DQDGNG+ID ++ K L Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKAL 33 >1TTX-A nrPDB Length = 109 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S + +R D D SG+++ EELK FL+ A + + T ++ D++ Sbjct: 40 SANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESE-----TKSLMAAADNDG 94 Query: 159 DGKLELTEMARLL 171 DGK+ E ++ Sbjct: 95 DGKIGAEEFQEMV 107 Score = 27.3 bits (59), Expect = 7.4, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 5/59 (8%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 KM + F D D +GY+DE EL L+ E ++L + K++MA +D Sbjct: 38 KMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKF-ESGAREL----TESETKSLMAAAD 91 >6DU8-A nrPDB Length = 805 Score = 28.9 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 E F +D+DGN +DE E + + +DL E+ Sbjct: 637 ELTATFTKFDRDGNRILDEKEQEKMRQDLEEE 668 >5VE9-A nrPDB Length = 91 Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 9/94 (9%) Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKF 181 + NF D+ K + K + D ++ D + DGK+ E + KF Sbjct: 5 HMANFDFDVWRKKYMRWMNHKKSRVMDFFRRI-DKDQDGKITRQEF-----IDGILASKF 58 Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 K+ E +++D+DG+GYID E A L Sbjct: 59 PTTKL---EMTAVADIFDRDGDGYIDYYEFVAAL 89 >2M8U-A nrPDB Length = 77 Score = 28.5 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 11/26 (42%), Positives = 20/26 (76%) Query: 193 KAFELYDQDGNGYIDENELDALLKDL 218 +AF+++D+DGNGY+ + L +L +L Sbjct: 15 EAFKVFDRDGNGYVTVDYLRKVLNEL 40 >4WPX-A nrPDB Length = 177 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 38/165 (23%), Positives = 74/165 (44%), Gaps = 27/165 (16%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTF--VDQYGQRD-- 69 S+ FE+ FD++ G L +E + +++ L G +L P+ +T+ + ++GQR Sbjct: 29 SEAFEL---FDSNKDGLLSYEEFRFVLRAL-------GFDL-PKQQTYDMLVRHGQRPAN 77 Query: 70 ---DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 126 D + V L T + +Q +E + +R +D D G I ++L+ Sbjct: 78 WPHDQECPPVYRQFNLATAQALAGTL-IRQRDPRDELRRAFRLFDVDGKGMITEDDLRK- 135 Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + ++ + D + M++ FDSN G ++ E RL+ Sbjct: 136 ---VCQQVGNNIPDADIQ----AMIEEFDSNGKGGVDEDEFLRLM 173 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 7/42 (16%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEK---NKQDLDI 228 E +AF L+D DG G I E++ L+ +C++ N D DI Sbjct: 112 ELRRAFRLFDVDGKGMITEDD----LRKVCQQVGNNIPDADI 149 >5XXB-F nrPDB Length = 258 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 9/67 (13%) Query: 34 KELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFR 93 KE +NLI+ ++A+ K G PE K + + GI +LA P + L LFR Sbjct: 67 KERENLIKLKREAKAKGGFYKEPEAKVILATRIK------GINKLA---PKPKMILRLFR 117 Query: 94 CQQLKSC 100 +QL + Sbjct: 118 LRQLHNA 124 >4YZB-A nrPDB Length = 491 Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust. Identities = 28/132 (21%), Positives = 62/132 (46%), Gaps = 14/132 (10%) Query: 90 LLFRCQQLKSCEEFM---KTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV---DDTKL 143 LL+ +L + EE + K +++ D + G ++ +EL +L++ + V D + + Sbjct: 325 LLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAI 384 Query: 144 AEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGN 203 + +L D + +G +E +E + ++ L + + +AF ++D DG+ Sbjct: 385 EFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLSR--------QRLERAFGMFDADGS 436 Query: 204 GYIDENELDALL 215 G I +EL + Sbjct: 437 GKISSSELATIF 448 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 26/109 (23%), Positives = 45/109 (41%), Gaps = 18/109 (16%) Query: 111 DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 D D +GFIE E D KT+ + E +FD++ GK+ +E+A + Sbjct: 396 DFDKNGFIEYSEFVTVAMD-----RKTLLSRQRLERA---FGMFDADGSGKISSSELATI 447 Query: 171 LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 V E + + + + D++ +G +D E +L LC Sbjct: 448 FGVSE----------VDSETWRRVLAEVDRNNDGEVDFEEFRQMLLKLC 486 >2FGE-A nrPDB Length = 995 Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust. Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 26/120 (21%) Query: 102 EFMKTW-RKYDTDHSGFIETEELKNFLKDLLEK----ANKTVDDTKLAEYTDLMLKLFD- 155 EF+ T +K D D G + L+ + LL + N T D L + K D Sbjct: 725 EFLHTLEKKVDEDWEGI--SSSLEEIRRSLLARNGCIVNMTADGKSLTNVEKSVAKFLDL 782 Query: 156 ---------SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 DG+L L A ++P Q N++ K I G Y+ DG+ Y+ Sbjct: 783 LPENPSGGLVTWDGRLPLRNEAIVIPTQVNYVGKAGNIYSTG---------YELDGSAYV 833 >5XJC-J nrPDB Length = 848 Score = 28.1 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 9/90 (10%) Query: 95 QQLKSCEE------FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT-VDDTKLAEYT 147 + +++CEE +++WR ++ + + E + + + ++K K DD A + Sbjct: 740 KTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVDKLMPEKVKKRRKVQTDDGSDAGWE 799 Query: 148 DLMLKLF--DSNNDGKLELTEMARLLPVQE 175 + +F D+ N L+L MA+L Q+ Sbjct: 800 EYFDYIFPEDAANQPNLKLLAMAKLWKKQQ 829 >3J04-B nrPDB Length = 143 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 31/126 (24%), Positives = 52/126 (41%), Gaps = 27/126 (21%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 +EF + + D + GFI+ E+ L D+L K D EY + M+ S Sbjct: 6 IQEFKEAFNMIDQNRDGFIDKED----LHDMLASMGKNPTD----EYLEGMM----SEAP 53 Query: 160 GKLELTEMARLLPVQENFLLKFQGIKMCGKE----FNKAFELYDQDGNGYIDENELDALL 215 G P+ L G K+ G + AF +D++ +G+I E+ L LL Sbjct: 54 G-----------PINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELL 102 Query: 216 KDLCEK 221 + ++ Sbjct: 103 TTMGDR 108 Score = 27.7 bits (60), Expect = 5.4, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQD 225 +EF +AF + DQ+ +G+ID+ +L +L + KN D Sbjct: 7 QEFKEAFNMIDQNRDGFIDKEDLHDMLASMG-KNPTD 42 >4N5X-A nrPDB Length = 199 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 21/100 (21%) Query: 111 DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 D + G ++ EE +LKD +K L K D NNDGK+E +E+ + Sbjct: 68 DVNKDGKLDFEEFMKYLKDHEKKMK-------------LAFKSLDKNNDGKIEASEIVQ- 113 Query: 171 LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 L+ G+ + ++ + D DG +D NE Sbjct: 114 -------SLQTLGLTISEQQAELILQSIDVDGTMTVDWNE 146 >1P2Z-A nrPDB Length = 967 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%) Query: 110 YDTDHSGFIETEELKN----FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 Y+ + GF E K+ F ++ + + VDDTK EY + + L NN G Sbjct: 789 YNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKEYQQVGI-LHQHNNSG 842 >4ZCV-A nrPDB Length = 165 Score = 28.1 bits (61), Expect = 3.9, Method: Compositional matrix adjust. Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 21/100 (21%) Query: 111 DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 D + G ++ EE +LKD +K L K D NNDGK+E +E+ + Sbjct: 59 DVNKDGKLDFEEFMKYLKDHEKKMK-------------LAFKSLDKNNDGKIEASEIVQ- 104 Query: 171 LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 L+ G+ + ++ + D DG +D NE Sbjct: 105 -------SLQTLGLTISEQQAELILQSIDVDGTMTVDWNE 137 >2KLD-A nrPDB Length = 123 Score = 28.1 bits (61), Expect = 4.1, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 181 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNIT 232 +G E F YDQDG+ + E+E + DL EK ++DLD+++ + Sbjct: 72 LKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDL-EKEREDLDLDHSS 122 >1S1E-A nrPDB Length = 224 Score = 28.1 bits (61), Expect = 4.1, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Query: 106 TWRKYDTDHSGFIETEELKNFLK---DLLEKANKTV--DDTKLAEYTDLMLKLFDSNNDG 160 T+ YD + G+I EE+ + +K D++ K V +DT ++ D+ + D N DG Sbjct: 130 TFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTP-RQHVDVFFQKMDKNKDG 188 Query: 161 KLELTE 166 + L E Sbjct: 189 IVTLDE 194 >2KQ6-A nrPDB Length = 78 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 181 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNIT 232 +G E F YDQDG+ + E+E + DL EK ++DLD+++ + Sbjct: 26 LKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDL-EKEREDLDLDHSS 76 >1S6C-A nrPDB Length = 183 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLK---DLLEKANKTV--DDTKLAEYTDLMLKLFD 155 E+ T+ YD + G+I EE+ + +K D++ K V +DT ++ D+ + D Sbjct: 92 EKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTP-RQHVDVFFQKMD 150 Query: 156 SNNDGKLELTEM 167 N DG + L E Sbjct: 151 KNKDGIVTLDEF 162 >2L2E-A nrPDB Length = 190 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 15/82 (18%) Query: 139 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELY 198 D + AEY + +FD++ +G ++ E L V L + I AF+LY Sbjct: 60 DPSAFAEY---VFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIW--------AFQLY 108 Query: 199 DQDGNGYIDENEL----DALLK 216 D D NG I +E+ DA+ K Sbjct: 109 DLDNNGLISYDEMLRIVDAIYK 130 >2M29-A nrPDB Length = 171 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 40/144 (27%) Query: 106 TWRKYDTDHSGFIETEELKNFLK---------DLLEKANKT-------VD--------DT 141 + ++DTD G+I EL + ++ +LLE + VD Sbjct: 33 AFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISP 92 Query: 142 KLAEYTDLMLKL---------FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 KL E T ML + FD + DG++ + E+ + P G + G E + Sbjct: 93 KLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPA-------LLGEPLEGTELD 145 Query: 193 KAFELYDQDGNGYIDENELDALLK 216 + D +G+G ID +E +L Sbjct: 146 EMLREMDLNGDGTIDFDEFVMMLS 169 >6D1W-A nrPDB Length = 740 Score = 27.7 bits (60), Expect = 4.7, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDIN 229 E F YDQDG+ + E+E + DL EK ++DLD++ Sbjct: 702 EIEAIFTKYDQDGDQELTEHEHQQMRDDL-EKEREDLDLD 740 >2KSZ-A nrPDB Length = 76 Score = 27.7 bits (60), Expect = 4.7, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 20/29 (68%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDL 218 +F +AF L+D+DG+G I EL +++ L Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSL 39 >1R9Q-A nrPDB Length = 309 Score = 27.3 bits (59), Expect = 6.0, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 4/34 (11%) Query: 136 KTVDDTKLAEYTDL----MLKLFDSNNDGKLELT 165 KT D K+ L + KLFD+N DGK +LT Sbjct: 101 KTADQYKITNIAQLKDPKIAKLFDTNGDGKADLT 134 >4OCI-A nrPDB Length = 146 Score = 27.3 bits (59), Expect = 6.4, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 20/26 (76%) Query: 193 KAFELYDQDGNGYIDENELDALLKDL 218 ++F L+D DG+GY+ NE ++L++ L Sbjct: 10 ESFLLFDGDGDGYLTLNEFESLVRVL 35 Score = 27.3 bits (59), Expect = 7.6, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 17/26 (65%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQEL 43 E +L FD DG GYL E ++L++ L Sbjct: 10 ESFLLFDGDGDGYLTLNEFESLVRVL 35 >3JBH-C nrPDB Length = 156 Score = 27.3 bits (59), Expect = 6.7, Method: Compositional matrix adjust. Identities = 34/148 (22%), Positives = 69/148 (46%), Gaps = 24/148 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 A + FEI +D +G G ++ ++L +L++ L+ P + V + G D Sbjct: 12 AREHFEI---YDWEGEGKIDARDLGDLLR---------SLDCKPTL-AMVKKNGGSDKRG 58 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + L LP F + + +++ + E+FM+ + YD +G + EL + L L E Sbjct: 59 EKKLTLEEFLPI---FSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGE 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDG 160 + + D + E ++++ D ++DG Sbjct: 116 R----LTDIECEE----IMRVCDEDDDG 135 >6IIE-A nrPDB Length = 93 Score = 27.3 bits (59), Expect = 7.1, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 194 AFELYDQDGNGYIDENELDALLKDLCEKNKQ-DLDINNITTYKKNIM 239 F+LYD D NG +D +E+D ++ + + D D++ + + +M Sbjct: 14 TFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMM 60 >3MZL-B nrPDB Length = 345 Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 85 EENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLA 144 EE++ LL + + EEF+K +D D SG IE KN + ++ A K + L Sbjct: 77 EEDWNLLEKLS-MDGTEEFLKEALAFDNDESGNIEQTISKNLVSGNIKSAVKNSLENDL- 134 Query: 145 EYTDLMLKLFDSNND 159 + M+ DSNN+ Sbjct: 135 -LMEAMVIALDSNNE 148 >3BOW-B nrPDB Length = 184 Score = 27.3 bits (59), Expect = 7.4, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 14/94 (14%) Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 + EL N L ++ + D + M+ + DS+ GKL E L N Sbjct: 31 VSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLW----NN 86 Query: 178 LLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 + K+QGI ++ +D D +G I NEL Sbjct: 87 IKKWQGI----------YKRFDTDRSGTIGSNEL 110 >1QXP-A nrPDB Length = 900 Score = 26.9 bits (58), Expect = 8.1, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 23/96 (23%) Query: 34 KELQNLIQELQQARKKA-----GLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENF 88 KELQ ++ + K LE M +D+ G +GK+G+VE + N+ Sbjct: 553 KELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDG---NGKLGLVEFNILWNRIRNY 609 Query: 89 LLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 L +F RK+D D SG + E++ Sbjct: 610 LTIF---------------RKFDLDKSGSMSAYEMR 630 >3VF1-A nrPDB Length = 698 Score = 26.9 bits (58), Expect = 8.8, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWR-----KYDTDHSGFIETEELKNFLKD 129 + E +LP ++ + Q+ K E K ++ +Y D GF++ EE K+ KD Sbjct: 133 VYEGKAILPNSKDNVKTIAEQRTKEVSENKKLYKWGTDPRYVQDLPGFVDAEEPKSLPKD 192 Query: 130 L--LEKANKTVDDTKLAEYTDLML 151 + ++A ++ LA++ +L L Sbjct: 193 VQFTDEATSSLFRVGLADFANLGL 216 >2E6W-A nrPDB Length = 100 Score = 26.9 bits (58), Expect = 9.0, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 18/25 (72%) Query: 194 AFELYDQDGNGYIDENELDALLKDL 218 AF LYD + +GYI + E+ A++K + Sbjct: 14 AFNLYDINKDGYITKEEMLAIMKSI 38 >1NP8-A nrPDB Length = 159 Score = 26.9 bits (58), Expect = 9.0, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 14/94 (14%) Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 + EL N L ++ + D + M+ + DS+ GKL E L N Sbjct: 27 VSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLW----NN 82 Query: 178 LLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 + K+QGI ++ +D D +G I NEL Sbjct: 83 IKKWQGI----------YKRFDTDRSGTIGSNEL 106 >1KFU-L nrPDB Length = 699 Score = 26.9 bits (58), Expect = 9.5, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 23/50 (46%) Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 I EL+ L+ +L K D E +M+ + DS+ GKL L E Sbjct: 547 ISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 596 >6HLX-A nrPDB Length = 492 Score = 26.9 bits (58), Expect = 9.6, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 7/54 (12%) Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 180 + DLL+K TVD + +K++D+ D LEL+ + + ++N+ +K Sbjct: 413 INDLLDKGRATVDKAE-------RVKIYDAFVDRALELSPLVYFMWREQNYAVK 459 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2G9B-A nrPDB 294 3e-80 2Q4U-A nrPDB 208 2e-54 4IL1-A nrPDB 175 2e-44 3U0K-A nrPDB 169 1e-42 4OY4-A nrPDB 169 1e-42 3EK4-A nrPDB 163 6e-41 5UKG-A nrPDB 161 3e-40 4I2Y-A nrPDB 160 4e-40 3WFN-B nrPDB 146 8e-36 2N6A-A nrPDB 143 9e-35 2F2P-A nrPDB 143 9e-35 6O20-F nrPDB 141 3e-34 6HCS-A nrPDB 138 4e-33 4E53-A nrPDB 137 4e-33 5A2H-A nrPDB 133 1e-31 1GGZ-A nrPDB 131 2e-31 5I0I-E nrPDB 131 3e-31 1CLM-A nrPDB 130 6e-31 4JWQ-A nrPDB 128 3e-30 3O4Y-A nrPDB 127 4e-30 3K21-A nrPDB 125 2e-29 2L1W-A nrPDB 118 4e-27 2LMV-A nrPDB 117 5e-27 1TOP-A nrPDB 117 6e-27 2TN4-A nrPDB 116 1e-26 5E37-A nrPDB 113 1e-25 3QRX-A nrPDB 107 5e-24 3KF9-A nrPDB 99 8e-22 5T7C-A nrPDB 92 2e-19 2LC5-A nrPDB 92 3e-19 1BJF-A nrPDB 91 4e-19 2R2I-A nrPDB 88 6e-18 2LCP-A nrPDB 82 2e-16 6EPA-A nrPDB 80 7e-16 5XND-A nrPDB 70 8e-13 2NLN-A nrPDB 58 4e-09 5CPV-A nrPDB 56 1e-08 Sequences not found previously or not previously below threshold: 2LHI-A nrPDB 105 2e-23 5D43-A nrPDB 99 2e-21 4DS7-A nrPDB 98 4e-21 1LKJ-A nrPDB 98 5e-21 2GGM-A nrPDB 98 5e-21 2LAP-A nrPDB 93 2e-19 1DTL-A nrPDB 91 5e-19 2OBH-A nrPDB 90 7e-19 2LHH-A nrPDB 88 3e-18 3HZT-A nrPDB 87 8e-18 5JN2-A nrPDB 86 2e-17 3LIJ-A nrPDB 84 4e-17 5M6C-E nrPDB 84 6e-17 4MVF-A nrPDB 84 6e-17 1S6I-A nrPDB 82 2e-16 3FWC-A nrPDB 81 6e-16 2M29-A nrPDB 80 1e-15 3PM8-A nrPDB 79 1e-15 4YZB-A nrPDB 79 1e-15 5ZOR-A nrPDB 79 1e-15 3IFK-A nrPDB 79 2e-15 3NCG-A nrPDB 79 2e-15 2NA0-A nrPDB 79 2e-15 5H7D-E nrPDB 79 2e-15 2BL0-B nrPDB 78 5e-15 4RGJ-A nrPDB 78 6e-15 5COC-A nrPDB 77 7e-15 3L19-A nrPDB 76 1e-14 3KHE-A nrPDB 76 1e-14 3Q5I-A nrPDB 76 1e-14 1GGW-A nrPDB 76 1e-14 2AAO-A nrPDB 76 2e-14 2BL0-C nrPDB 76 2e-14 1W7I-B nrPDB 75 3e-14 4Q57-A nrPDB 74 6e-14 2I94-A nrPDB 73 1e-13 3JAX-C nrPDB 73 1e-13 2RO8-A nrPDB 73 2e-13 2KN2-A nrPDB 72 2e-13 1FW4-A nrPDB 72 2e-13 2HF5-A nrPDB 72 2e-13 2KZ2-A nrPDB 71 4e-13 2I08-A nrPDB 71 5e-13 4ORC-B nrPDB 71 7e-13 4WPX-A nrPDB 70 8e-13 2M5E-A nrPDB 70 9e-13 2JNF-A nrPDB 70 1e-12 5MWC-D nrPDB 69 1e-12 1JBA-A nrPDB 69 2e-12 2JUL-A nrPDB 69 2e-12 2RO9-A nrPDB 69 2e-12 2W4G-C nrPDB 68 3e-12 2D8N-A nrPDB 68 3e-12 2JU0-A nrPDB 68 4e-12 3J04-B nrPDB 68 5e-12 1TNP-A nrPDB 68 5e-12 2L2E-A nrPDB 68 6e-12 1TRF-A nrPDB 67 8e-12 2LV7-A nrPDB 67 9e-12 5H53-C nrPDB 67 9e-12 2ROB-A nrPDB 66 1e-11 2GGZ-A nrPDB 65 2e-11 5B8I-B nrPDB 65 3e-11 1N2D-A nrPDB 65 3e-11 6FSA-D nrPDB 63 1e-10 3DD4-A nrPDB 63 2e-10 2KSZ-A nrPDB 62 2e-10 5TBY-C nrPDB 61 5e-10 3JBH-C nrPDB 61 7e-10 2AMI-A nrPDB 60 8e-10 3AAJ-A nrPDB 60 9e-10 2B1U-A nrPDB 60 1e-09 5B7X-A nrPDB 59 2e-09 1JC2-A nrPDB 59 2e-09 4ZCV-A nrPDB 58 3e-09 1OQP-A nrPDB 58 4e-09 2BEC-A nrPDB 58 5e-09 4N5X-A nrPDB 57 9e-09 2K7C-A nrPDB 57 1e-08 1M39-A nrPDB 56 1e-08 1F55-A nrPDB 56 1e-08 4PAL-A nrPDB 56 2e-08 1ZMZ-A nrPDB 56 2e-08 1A75-A nrPDB 55 3e-08 1Y1X-A nrPDB 54 4e-08 3DTP-E nrPDB 54 5e-08 1QXP-A nrPDB 54 6e-08 2N7L-C nrPDB 54 6e-08 1I84-U nrPDB 54 6e-08 2KYF-A nrPDB 54 6e-08 1S1E-A nrPDB 54 7e-08 1BU3-A nrPDB 54 7e-08 5ZGM-A nrPDB 54 8e-08 2KQY-A nrPDB 53 1e-07 2K2I-A nrPDB 53 1e-07 5VLN-A nrPDB 53 1e-07 1S6C-A nrPDB 53 1e-07 5TBY-E nrPDB 53 1e-07 1TTX-A nrPDB 53 1e-07 3E3R-A nrPDB 53 1e-07 4GJF-A nrPDB 53 1e-07 2M97-A nrPDB 53 2e-07 1O1A-B nrPDB 53 2e-07 2MBX-A nrPDB 53 2e-07 2E30-A nrPDB 53 2e-07 1V1G-A nrPDB 52 2e-07 2JNX-A nrPDB 52 2e-07 4OKH-A nrPDB 52 3e-07 3DF0-A nrPDB 52 3e-07 1KFU-L nrPDB 52 3e-07 2M8U-A nrPDB 51 4e-07 1RTP-1 nrPDB 51 4e-07 1RK9-A nrPDB 51 4e-07 5JOL-A nrPDB 51 4e-07 3I5I-C nrPDB 51 5e-07 5PAL-A nrPDB 51 5e-07 5ZH6-A nrPDB 51 5e-07 5JOJ-A nrPDB 51 5e-07 2E6W-A nrPDB 51 5e-07 1OZS-A nrPDB 51 6e-07 4P5X-A nrPDB 51 6e-07 2ZFD-A nrPDB 50 8e-07 5YPX-A nrPDB 50 8e-07 3I5H-B nrPDB 50 1e-06 5H53-B nrPDB 50 1e-06 1DGU-A nrPDB 50 1e-06 2N8Y-A nrPDB 49 2e-06 1G33-A nrPDB 49 2e-06 3PAT-A nrPDB 49 2e-06 1QX2-A nrPDB 49 2e-06 1UHN-A nrPDB 49 2e-06 5OTJ-D nrPDB 49 2e-06 2LM5-A nrPDB 49 2e-06 3KPX-A nrPDB 49 2e-06 2K2A-A nrPDB 49 3e-06 1DFK-Y nrPDB 49 3e-06 5Z1Q-A nrPDB 48 3e-06 2HPS-A nrPDB 48 3e-06 1B7T-Y nrPDB 48 3e-06 1C7W-A nrPDB 48 4e-06 1JUO-A nrPDB 48 4e-06 2EC6-B nrPDB 48 5e-06 1YX7-A nrPDB 48 5e-06 1JFJ-A nrPDB 47 7e-06 5MRA-A nrPDB 47 8e-06 1SR6-C nrPDB 46 1e-05 2LVK-A nrPDB 46 1e-05 1NYA-A nrPDB 46 1e-05 2OS8-B nrPDB 46 1e-05 1S36-A nrPDB 46 2e-05 3MSE-B nrPDB 46 2e-05 1JF0-A nrPDB 46 2e-05 3TS5-B nrPDB 46 2e-05 1GJY-A nrPDB 46 2e-05 4D1E-A nrPDB 46 2e-05 2JOJ-A nrPDB 46 2e-05 2K7B-A nrPDB 45 3e-05 1KFX-S nrPDB 45 3e-05 5I2L-A nrPDB 45 3e-05 1H4B-A nrPDB 45 3e-05 3SIA-A nrPDB 45 3e-05 1F4Q-A nrPDB 45 3e-05 4OCI-A nrPDB 45 3e-05 1SJJ-A nrPDB 44 7e-05 2OPO-A nrPDB 43 1e-04 4I5K-A nrPDB 43 1e-04 1Q80-A nrPDB 43 1e-04 2VRG-A nrPDB 43 2e-04 3BOW-B nrPDB 43 2e-04 3A4U-B nrPDB 43 2e-04 1SL8-A nrPDB 43 2e-04 2M1U-A nrPDB 43 2e-04 3LCP-C nrPDB 43 2e-04 6EAZ-A nrPDB 42 2e-04 3AKA-A nrPDB 42 3e-04 3TZ1-A nrPDB 42 3e-04 5VT9-A nrPDB 42 3e-04 5VE9-A nrPDB 42 3e-04 2FCE-A nrPDB 41 4e-04 5E1J-A nrPDB 41 4e-04 4YGB-B nrPDB 41 4e-04 1NP8-A nrPDB 41 4e-04 1UHK-A nrPDB 41 6e-04 5W1A-B nrPDB 41 7e-04 1S6J-A nrPDB 41 8e-04 4L9M-A nrPDB 40 0.001 2LVV-A nrPDB 40 0.001 6IIE-A nrPDB 40 0.001 4P5W-A nrPDB 40 0.001 4I5L-B nrPDB 39 0.002 6AGH-A nrPDB 39 0.002 4MSP-A nrPDB 39 0.002 4NQG-A nrPDB 38 0.004 4MEW-A nrPDB 38 0.004 3A8R-A nrPDB 38 0.007 1NSH-A nrPDB 37 0.007 1TIZ-A nrPDB 37 0.007 4NSC-A nrPDB 37 0.007 5XOP-A nrPDB 37 0.009 2G2B-A nrPDB 37 0.009 1ZFS-A nrPDB 36 0.012 2M7M-A nrPDB 36 0.014 2SAS-A nrPDB 36 0.014 2LUC-A nrPDB 36 0.015 6D1W-A nrPDB 36 0.016 1BOD-A nrPDB 36 0.016 5MKE-A nrPDB 36 0.017 2NCO-A nrPDB 36 0.017 2L0P-A nrPDB 36 0.025 2VTG-A nrPDB 35 0.032 3H4S-E nrPDB 35 0.037 6MI5-X nrPDB 34 0.048 3POC-A nrPDB 34 0.055 1CB1-A nrPDB 34 0.055 5HYD-A nrPDB 34 0.060 2MA2-A nrPDB 34 0.061 2KGR-A nrPDB 34 0.063 2AUC-A nrPDB 34 0.068 6AGI-A nrPDB 34 0.069 2D58-A nrPDB 34 0.087 1IJ5-A nrPDB 34 0.088 2PMY-A nrPDB 33 0.11 1DJX-A nrPDB 33 0.12 1WY9-A nrPDB 33 0.12 1QLS-A nrPDB 33 0.13 3CS1-A nrPDB 33 0.16 2KHN-A nrPDB 32 0.21 2I18-A nrPDB 32 0.23 2L50-A nrPDB 32 0.24 2Y5I-A nrPDB 32 0.29 4AOM-A nrPDB 32 0.32 3MZL-B nrPDB 31 0.41 6DU8-A nrPDB 31 0.42 5CSF-A nrPDB 31 0.42 2MJW-B nrPDB 31 0.47 5X2E-A nrPDB 31 0.48 1IQ3-A nrPDB 31 0.51 3NSO-A nrPDB 31 0.56 4GFT-A nrPDB 31 0.57 2WCE-A nrPDB 31 0.58 2M7L-A nrPDB 31 0.72 6DS2-B nrPDB 30 1.1 5CUU-A nrPDB 29 1.5 5HLO-A nrPDB 29 1.8 6QAA-A nrPDB 29 2.5 2MHH-A nrPDB 29 2.5 3AHE-A nrPDB 29 2.6 2IXN-A nrPDB 29 2.6 2JMM-A nrPDB 29 2.7 5ZCR-A nrPDB 28 3.5 1KQV-A nrPDB 28 3.9 1J37-A nrPDB 28 4.1 4WNZ-A nrPDB 28 4.2 4BHK-A nrPDB 27 5.8 6EMI-A nrPDB 27 6.1 4YBH-B nrPDB 27 6.1 4A0K-A nrPDB 27 6.4 5VP3-A nrPDB 27 7.6 6MZL-S nrPDB 27 9.7 3ABB-A nrPDB 27 9.8 >2G9B-A nrPDB Length = 263 Score = 294 bits (752), Expect = 3e-80, Method: Composition-based stats. Identities = 257/261 (98%), Positives = 259/261 (99%) Query: 1 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKT 60 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQEL QARKKAGLELSPEMKT Sbjct: 3 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKT 62 Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET Sbjct: 63 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 122 Query: 121 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 180 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK Sbjct: 123 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 182 Query: 181 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMA 240 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQ+LDINNI+TYKKNIMA Sbjct: 183 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQELDINNISTYKKNIMA 242 Query: 241 LSDGGKLYRTDLALILCAGDN 261 LSDGGKLYRTDLALIL AGDN Sbjct: 243 LSDGGKLYRTDLALILSAGDN 263 >2Q4U-A nrPDB Length = 272 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 105/259 (40%), Positives = 159/259 (61%), Gaps = 13/259 (5%) Query: 11 ITASQFFEIWLHFDADGSGYLEGKEL----QNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + A+ F +IW HFDAD +GY+EGKEL ++++++LQ K + K+F+ Y Sbjct: 8 LDAAGFLQIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYD 67 Query: 67 QRDDGKIGIVELAHV-LPTEENFLLLFRCQ-QLKSCEEFMKTWRKYDTDHSGFIETEELK 124 DG++ I ELA++ LP EENFLL+FR + L + EFMK WRKYD D SG+I ELK Sbjct: 68 ATFDGRLQIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELK 127 Query: 125 NFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGI 184 NFLKDL + K + KL EYTD M+K+FD N DG+L+L ++AR+L +QENFLL+F+ Sbjct: 128 NFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMD 187 Query: 185 KMC----GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMA 240 ++F K F YD G ++ E+D +KD+ E + + ++ +++ ++ Sbjct: 188 ASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDMMELVRPSISGGDLDKFRECLLT 247 Query: 241 LSD---GGKLYRTDLALIL 256 D GK+ +++LAL L Sbjct: 248 HCDMNKDGKIQKSELALCL 266 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 50/173 (28%), Positives = 93/173 (53%), Gaps = 5/173 (2%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQEL--QQARKKAGLELSPEMKTFVDQ 64 ++ L + +F +IW +DAD SGY+ EL+N +++L Q +K +L + Sbjct: 97 EAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKI 156 Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCE---EFMKTWRKYDTDHSGFIETE 121 + + DG++ + +LA +L +ENFLL F+ E +F K + YD +G +E Sbjct: 157 FDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGP 216 Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 E+ F+KD++E ++ L ++ + +L D N DGK++ +E+A L ++ Sbjct: 217 EVDGFVKDMMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSELALCLGLK 269 >4IL1-A nrPDB Length = 823 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 45/212 (21%), Positives = 84/212 (39%), Gaps = 36/212 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 63 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 64 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQG--------- 183 K E D M++ D + DG++ E +++ + G Sbjct: 116 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLE 167 Query: 184 -----IKMCGKEFNKAFELYDQDGNGYIDENE 210 K K F+ D D +G + E Sbjct: 168 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEE 199 Score = 129 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGT 63 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 64 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 116 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 117 LTDE----EVDEMIREADIDGDG 135 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 47/247 (19%), Positives = 93/247 (37%), Gaps = 39/247 (15%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + E + FD DG+GY+ EL++++ L + E+ + + DG Sbjct: 82 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD------EEVDEMIREADIDGDG 135 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKS----------CEEFM---KTWRKYDTDHSGFI 118 ++ E ++ + S +E K ++K D D+SG + Sbjct: 136 QVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSL 195 Query: 119 ETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 EE ++ + + ++ +FD++ +G+++ E + Sbjct: 196 SVEEF------------MSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIE-------GV 236 Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNI-TTYKKN 237 +F ++ AF +YD D +GYI EL +LK + N +D + I N Sbjct: 237 SQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIN 296 Query: 238 IMALSDG 244 DG Sbjct: 297 ADKDGDG 303 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 62/166 (37%), Gaps = 24/166 (14%) Query: 9 SLITASQFFEI---WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQY 65 S A + + + D D SG L +E + + ELQQ ++ +D + Sbjct: 170 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-LPELQQNPL---------VQRVIDIF 219 Query: 66 GQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 +G++ E + + ++ +R YD D G+I EL Sbjct: 220 DTDGNGEVDFKEFIEGVSQFSV--------KGDKEQKLRFAFRIYDMDKDGYISNGELFQ 271 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 LK + + DT+L + D + D + DG++ E ++ Sbjct: 272 VLKMM---VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 314 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 29/81 (35%), Gaps = 1/81 (1%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + + +D D GY+ EL +++ + K +L + + + DG+I Sbjct: 247 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK-DTQLQQIVDKTIINADKDGDGRI 305 Query: 74 GIVELAHVLPTEENFLLLFRC 94 E V+ + + Sbjct: 306 SFEEFCAVVGGLDIHKKMVVD 326 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 4/66 (6%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNI 238 + Q + EF +AF L+D+DG+G I EL +++ L + N + ++ + + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ-NPTEAELQD---MINEV 56 Query: 239 MALSDG 244 A +G Sbjct: 57 DADGNG 62 >3U0K-A nrPDB Length = 442 Score = 169 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 24/172 (13%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 L I ++F E + FD DG G + KEL +++ L Q +A E++ + Sbjct: 295 RDQLTEEQI--AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMI 346 Query: 63 DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEE 122 ++ DG I E ++ + + S EE + +R +D D +G+I E Sbjct: 347 NEVDADGDGTIDFPEFLIMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAE 398 Query: 123 LKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 L++ + +L EK E D M++ D + DG++ E +++ + Sbjct: 399 LRHVMTNLGEKLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 442 Score = 130 bits (326), Expect = 7e-31, Method: Composition-based stats. Identities = 35/143 (24%), Positives = 62/143 (43%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ DG Sbjct: 305 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGDGT 356 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 357 IDFPEFLIMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 409 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 410 LTDE----EVDEMIREADIDGDG 428 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 36/85 (42%), Gaps = 6/85 (7%) Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGK--EFNKAFELYDQDGNGYIDENELDALLKDLC 219 + ++ + + + EF +AF L+D+DG+G I EL +++ L Sbjct: 275 VNFPSNGAVMQKKTKGWEPTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLG 334 Query: 220 EKNKQDLDINNITTYKKNIMALSDG 244 + N + ++ + + A DG Sbjct: 335 Q-NPTEAELQD---MINEVDADGDG 355 >4OY4-A nrPDB Length = 415 Score = 169 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 39/182 (21%), Positives = 78/182 (42%), Gaps = 22/182 (12%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ DG Sbjct: 17 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGDGT 70 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 71 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 122 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 K E D M++ D + DG++ E +++ + + + + + Sbjct: 123 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAKLECEKMYVRDGVLTGDIH 174 Query: 193 KA 194 A Sbjct: 175 MA 176 Score = 128 bits (322), Expect = 2e-30, Method: Composition-based stats. Identities = 35/143 (24%), Positives = 62/143 (43%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ DG Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGDGT 70 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 71 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 123 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 124 LTDE----EVDEMIREADIDGDG 142 Score = 62.5 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 34/83 (40%), Gaps = 6/83 (7%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + E + FD DG+GY+ EL++++ L + E+ + + DG Sbjct: 89 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD------EEVDEMIREADIDGDG 142 Query: 72 KIGIVELAHVLPTEENFLLLFRC 94 ++ E ++ + ++ Sbjct: 143 QVNYEEFVQMMTAKLECEKMYVR 165 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 14/132 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG G ++ E ++ ARK + E++ + + +G Sbjct: 52 TEAELQDMINEVDADGDGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNG 106 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I EL HV+ L + EE + R+ D D G + EE + L Sbjct: 107 YISAAELRHVMTNLGEKL---------TDEEVDEMIREADIDGDGQVNYEEFVQMMTAKL 157 Query: 132 EKANKTVDDTKL 143 E V D L Sbjct: 158 ECEKMYVRDGVL 169 Score = 42.1 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMAL 241 Q + EF +AF L+D+DG+G I EL +++ L + N + ++ + + A Sbjct: 11 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ-NPTEAELQD---MINEVDAD 66 Query: 242 SDG 244 DG Sbjct: 67 GDG 69 >3EK4-A nrPDB Length = 451 Score = 163 bits (413), Expect = 6e-41, Method: Composition-based stats. Identities = 39/172 (22%), Positives = 75/172 (43%), Gaps = 24/172 (13%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 L I ++F E + FD DG G + KEL +++ L Q +A E++ + Sbjct: 304 RDQLTEEQI--AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMI 355 Query: 63 DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEE 122 ++ +G I E ++ + + S EE + +R +D D +G+I E Sbjct: 356 NEVDADGNGTIDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAE 407 Query: 123 LKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 L++ + +L EK E D M++ D + DG++ E +++ + Sbjct: 408 LRHVMTNLGEKLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 451 Score = 128 bits (321), Expect = 2e-30, Method: Composition-based stats. Identities = 42/196 (21%), Positives = 81/196 (41%), Gaps = 23/196 (11%) Query: 49 KAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWR 108 K E+ E T V++ + I E ++L + + + + + EF + + Sbjct: 265 KTRAEVKFEGDTLVNRIELKG---IDFKEDGNILGHKLEYNTRDQLTEEQIA-EFKEAFS 320 Query: 109 KYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMA 168 +D D G I T+EL ++ L + + AE D M+ D++ +G ++ E Sbjct: 321 LFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGNGTIDFPEFL 372 Query: 169 RLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDI 228 ++ + +E +AF ++D+DGNGYI EL ++ +L EK + Sbjct: 373 TMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE--- 422 Query: 229 NNITTYKKNIMALSDG 244 + + DG Sbjct: 423 -EVDEMIREADIDGDG 437 >5UKG-A nrPDB Length = 419 Score = 161 bits (407), Expect = 3e-40, Method: Composition-based stats. Identities = 37/162 (22%), Positives = 75/162 (46%), Gaps = 22/162 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ DG Sbjct: 280 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGDGT 333 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 E ++ + ++ + + EE + +R +D D +G+I EL++ + DL E Sbjct: 334 FDFPEFLTMMARKMSYRV--------TEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGE 385 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 K E D M+++ D + DG++ E +++ + Sbjct: 386 KLTD--------EEVDEMIRVADIDGDGQVNYEEFVQMMTAK 419 Score = 129 bits (324), Expect = 1e-30, Method: Composition-based stats. Identities = 36/143 (25%), Positives = 65/143 (45%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + AE D M+ D++ DG Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE-------AELQD-MINEVDADGDGT 333 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 + E ++ + ++ ++ +E +AF ++D+DGNGYI EL ++ DL EK Sbjct: 334 FDFPEFLTMMARKMSY-------RVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEK 386 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 387 LTDE----EVDEMIRVADIDGDG 405 Score = 59.8 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 33/75 (44%), Gaps = 6/75 (8%) Query: 11 ITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 +T + E + FD DG+GY+ EL++++ +L + E+ + D Sbjct: 351 VTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTD------EEVDEMIRVADIDGD 404 Query: 71 GKIGIVELAHVLPTE 85 G++ E ++ + Sbjct: 405 GQVNYEEFVQMMTAK 419 Score = 50.6 bits (119), Expect = 6e-07, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG G + E ++ ARK + E++ + + +G Sbjct: 315 TEAELQDMINEVDADGDGTFDFPEFLTMM-----ARKMSYRVTEEEIREAFRVFDKDGNG 369 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 IG EL HV+ L + EE + R D D G + EE + Sbjct: 370 YIGAAELRHVMTDLGEKL---------TDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 418 Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 36/85 (42%), Gaps = 6/85 (7%) Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGK--EFNKAFELYDQDGNGYIDENELDALLKDLC 219 + ++ + G + EF +AF L+D+DG+G I EL +++ L Sbjct: 252 MNFPANGPVMQKKTLGWEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLG 311 Query: 220 EKNKQDLDINNITTYKKNIMALSDG 244 + N + ++ + + A DG Sbjct: 312 Q-NPTEAELQD---MINEVDADGDG 332 >4I2Y-A nrPDB Length = 421 Score = 160 bits (405), Expect = 4e-40, Method: Composition-based stats. Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 24/172 (13%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 L I ++F E + FD DG G + KEL +++ L Q +A E++ + Sbjct: 274 RDQLTEEQI--AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMI 325 Query: 63 DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEE 122 ++ DG E ++ + S EE + +R +D D +G+I E Sbjct: 326 NEVDADGDGTFDFPEFLTMMAR--------KMNDTDSEEEIREAFRVFDKDGNGYIGAAE 377 Query: 123 LKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 L++ + DL EK E D M+++ D + DG++ E +++ + Sbjct: 378 LRHVMTDLGEKLTD--------EEVDEMIRVADIDGDGQVNYEEFVQMMTAK 421 Score = 126 bits (317), Expect = 8e-30, Method: Composition-based stats. Identities = 38/174 (21%), Positives = 67/174 (38%), Gaps = 19/174 (10%) Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 G + + + + EF + + +D D G I T+EL ++ L Sbjct: 253 GTNFPPDGPVMQKKTMGWEATRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL 312 Query: 131 LEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKE 190 + + AE D M+ D++ DG + E ++ + N +E Sbjct: 313 GQNPTE-------AELQD-MINEVDADGDGTFDFPEFLTMMARKMN-------DTDSEEE 357 Query: 191 FNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +AF ++D+DGNGYI EL ++ DL EK + + + DG Sbjct: 358 IREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDE----EVDEMIRVADIDGDG 407 >3WFN-B nrPDB Length = 182 Score = 146 bits (368), Expect = 8e-36, Method: Composition-based stats. Identities = 37/180 (20%), Positives = 77/180 (42%), Gaps = 22/180 (12%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 16 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 69 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 70 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 121 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 K E D M++ D + DG++ E +++ + + + + + Sbjct: 122 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGEEVSAVVLQRAYR 173 Score = 110 bits (274), Expect = 8e-25, Method: Composition-based stats. Identities = 33/158 (20%), Positives = 64/158 (40%), Gaps = 19/158 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 18 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 69 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 70 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 122 Query: 222 NKQDLDINNITTYKKNIMALSDGGKLYRTDLALILCAG 259 + + + DG Y + ++ G Sbjct: 123 LTDE----EVDEMIREADIDGDGQVNYEEFVQMMTAKG 156 Score = 43.7 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 50/133 (37%), Gaps = 14/133 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E ++ ARK + E++ + + +G Sbjct: 51 TEAELQDMINEVDADGNGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNG 105 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I EL HV+ L + EE + R+ D D G + EE + Sbjct: 106 YISAAELRHVMTNLGEKL---------TDEEVDEMIREADIDGDGQVNYEEFVQMMTAKG 156 Query: 132 EKANKTVDDTKLA 144 + V L Sbjct: 157 GGGGEEVSAVVLQ 169 Score = 36.0 bits (81), Expect = 0.019, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 24/42 (57%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + Q + EF +AF L+D+DG+G I EL +++ L + Sbjct: 7 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 48 >2N6A-A nrPDB Length = 173 Score = 143 bits (360), Expect = 9e-35, Method: Composition-based stats. Identities = 37/160 (23%), Positives = 72/160 (45%), Gaps = 22/160 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 11 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 64 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 65 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 116 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 K E D M++ D + DG++ E +++ Sbjct: 117 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMT 148 Score = 109 bits (271), Expect = 2e-24, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 64 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 65 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 117 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 118 LTDE----EVDEMIREADIDGDG 136 Score = 52.1 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 31/81 (38%), Gaps = 6/81 (7%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + E + FD DG+GY+ EL++++ L + E+ + + DG++ Sbjct: 86 EIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD------EEVDEMIREADIDGDGQVN 139 Query: 75 IVELAHVLPTEENFLLLFRCQ 95 E ++ + Sbjct: 140 YEEFVQMMTGASTAAGSGWRK 160 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 30/133 (22%), Positives = 51/133 (38%), Gaps = 14/133 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E ++ ARK + E++ + + +G Sbjct: 46 TEAELQDMINEVDADGNGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNG 100 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I EL HV+ L + EE + R+ D D G + EE + Sbjct: 101 YISAAELRHVMTNLGEKL---------TDEEVDEMIREADIDGDGQVNYEEFVQMMTGAS 151 Query: 132 EKANKTVDDTKLA 144 A KLA Sbjct: 152 TAAGSGWRKIKLA 164 >2F2P-A nrPDB Length = 179 Score = 143 bits (359), Expect = 9e-35, Method: Composition-based stats. Identities = 37/185 (20%), Positives = 78/185 (42%), Gaps = 22/185 (11%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 63 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 64 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 K E D M++ D + DG++ E +++ + ++ + Sbjct: 116 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGAAARKEVIRNKIR 167 Query: 193 KAFEL 197 ++ Sbjct: 168 AIGKM 172 Score = 106 bits (265), Expect = 8e-24, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 63 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 64 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 116 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 117 LTDE----EVDEMIREADIDGDG 135 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 51/143 (35%), Gaps = 14/143 (9%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E ++ ARK + E++ + + +G Sbjct: 45 TEAELQDMINEVDADGNGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNG 99 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I EL HV+ L + EE + R+ D D G + EE + Sbjct: 100 YISAAELRHVMTNLGEKL---------TDEEVDEMIREADIDGDGQVNYEEFVQMMTAKG 150 Query: 132 EKANKTVDDTKLAEYTDLMLKLF 154 + + K+ Sbjct: 151 GGGGAAARKEVIRNKIRAIGKMA 173 Score = 35.2 bits (79), Expect = 0.032, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 24/42 (57%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + Q + EF +AF L+D+DG+G I EL +++ L + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 42 >6O20-F nrPDB Length = 169 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 37/162 (22%), Positives = 73/162 (45%), Gaps = 22/162 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 30 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 83 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 84 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 135 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 K E D M++ D + DG++ E +++ + Sbjct: 136 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAK 169 Score = 106 bits (265), Expect = 7e-24, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 32 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 83 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 84 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 136 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 137 LTDE----EVDEMIREADIDGDG 155 Score = 35.2 bits (79), Expect = 0.032, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 24/42 (57%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + Q + EF +AF L+D+DG+G I EL +++ L + Sbjct: 21 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 62 >6HCS-A nrPDB Length = 167 Score = 138 bits (346), Expect = 4e-33, Method: Composition-based stats. Identities = 38/166 (22%), Positives = 74/166 (44%), Gaps = 22/166 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 10 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 63 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++F+ +L E Sbjct: 64 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGE 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 K E D M++ D + DG++ E +++ + Sbjct: 116 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAKLEGT 153 Score = 103 bits (257), Expect = 7e-23, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 63 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL + +L EK Sbjct: 64 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEK 116 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 117 LTDE----EVDEMIREADIDGDG 135 Score = 50.2 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 31/77 (40%), Gaps = 6/77 (7%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + E + FD DG+GY+ EL++ + L + E+ + + DG++ Sbjct: 85 EIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTD------EEVDEMIREADIDGDGQVN 138 Query: 75 IVELAHVLPTEENFLLL 91 E ++ + L Sbjct: 139 YEEFVQMMTAKLEGTGL 155 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 48/122 (39%), Gaps = 14/122 (11%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E ++ ARK + E++ + + +G Sbjct: 45 TEAELQDMINEVDADGNGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNG 99 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I EL H + L + EE + R+ D D G + EE + L Sbjct: 100 YISAAELRHFMTNLGEKL---------TDEEVDEMIREADIDGDGQVNYEEFVQMMTAKL 150 Query: 132 EK 133 E Sbjct: 151 EG 152 Score = 34.4 bits (77), Expect = 0.053, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 24/42 (57%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + Q + EF +AF L+D+DG+G I EL +++ L + Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 42 >4E53-A nrPDB Length = 185 Score = 137 bits (345), Expect = 4e-33, Method: Composition-based stats. Identities = 38/175 (21%), Positives = 75/175 (42%), Gaps = 22/175 (12%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 17 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 70 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 71 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 122 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMC 187 K E D M++ D + DG++ E +++ + I+ Sbjct: 123 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGAATKIQAS 169 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 70 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 71 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 123 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 124 LTDE----EVDEMIREADIDGDG 142 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 14/116 (12%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E ++ ARK + E++ + + +G Sbjct: 52 TEAELQDMINEVDADGNGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNG 106 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 I EL HV+ L + EE + R+ D D G + EE + Sbjct: 107 YISAAELRHVMTNLGEKL---------TDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 34.4 bits (77), Expect = 0.046, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 24/42 (57%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + Q + EF +AF L+D+DG+G I EL +++ L + Sbjct: 8 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 49 >5A2H-A nrPDB Length = 149 Score = 133 bits (333), Expect = 1e-31, Method: Composition-based stats. Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 22/162 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 S+F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 10 ISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 63 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E +++ + + S EE + +R +D D +GFI EL++ + +L E Sbjct: 64 IDFPEFLNLMAR--------KMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGE 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 K E D M++ D + DG++ E +++ + Sbjct: 116 KLTD--------EEVDEMIREADVDGDGQINYEEFVKVMMAK 149 Score = 96.8 bits (239), Expect = 8e-21, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 58/147 (39%), Gaps = 19/147 (12%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 EF + + +D D G I T+EL ++ L + + M+ D++ Sbjct: 8 DQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEA--------ELQDMINEVDAD 59 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 +G ++ E L+ + +E +AF ++D+D NG+I EL ++ + Sbjct: 60 GNGTIDFPEFLNLMARKM-------KDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTN 112 Query: 218 LCEKNKQDLDINNITTYKKNIMALSDG 244 L EK + + + DG Sbjct: 113 LGEKLTDE----EVDEMIREADVDGDG 135 Score = 47.5 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + E + FD D +G++ EL++++ L + E+ + + DG Sbjct: 82 SEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTD------EEVDEMIREADVDGDG 135 Query: 72 KIGIVELAHVL 82 +I E V+ Sbjct: 136 QINYEEFVKVM 146 Score = 38.3 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 14/116 (12%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E NL+ ARK + E+K + + +G Sbjct: 45 TEAELQDMINEVDADGNGTIDFPEFLNLM-----ARKMKDTDSEEELKEAFRVFDKDQNG 99 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 I EL HV+ L + EE + R+ D D G I EE + Sbjct: 100 FISAAELRHVMTNLGEKL---------TDEEVDEMIREADVDGDGQINYEEFVKVM 146 Score = 34.4 bits (77), Expect = 0.052, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 23/42 (54%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + Q EF +AF L+D+DG+G I EL +++ L + Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQ 42 >1GGZ-A nrPDB Length = 148 Score = 131 bits (330), Expect = 2e-31, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 74/162 (45%), Gaps = 22/162 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + +EL +++ L Q +A E++ + + + +G Sbjct: 9 VTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEA------ELRDMMSEIDRDGNGT 62 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + E ++ + + + EE + +R +D D +GF+ EL++ + L E Sbjct: 63 VDFPEFLGMMAR--------KMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGE 114 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 K + E D M++ D++ DG++ E R+L + Sbjct: 115 KLSD--------EEVDEMIRAADTDGDGQVNYEEFVRVLVSK 148 Score = 100 bits (248), Expect = 6e-22, Method: Composition-based stats. Identities = 30/144 (20%), Positives = 56/144 (38%), Gaps = 19/144 (13%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EF + + +D D G I T EL ++ L + + M+ D + +G Sbjct: 10 TEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEA--------ELRDMMSEIDRDGNG 61 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ E ++ + +E +AF ++D+DGNG++ EL ++ L E Sbjct: 62 TVDFPEFLGMMARKM-------KDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGE 114 Query: 221 KNKQDLDINNITTYKKNIMALSDG 244 K L + + DG Sbjct: 115 K----LSDEEVDEMIRAADTDGDG 134 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 14/116 (12%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ D DG+G ++ E ++ ARK + E++ + + +G Sbjct: 44 TEAELRDMMSEIDRDGNGTVDFPEFLGMM-----ARKMKDTDNEEEIREAFRVFDKDGNG 98 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 + EL HV+ L S EE + R DTD G + EE L Sbjct: 99 FVSAAELRHVMTRLGEKL---------SDEEVDEMIRAADTDGDGQVNYEEFVRVL 145 >5I0I-E nrPDB Length = 145 Score = 131 bits (329), Expect = 3e-31, Method: Composition-based stats. Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 22/160 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + D DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 8 IAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 61 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S EE + +R +D D +G+I EL++ + +L E Sbjct: 62 IDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGE 113 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 K E D M++ D + DG++ E +++ Sbjct: 114 KLTD--------EEVDEMIREADIDGDGQVNYEEFVQMMT 145 Score = 99 bits (247), Expect = 1e-21, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + D D G I T+EL ++ L + + M+ D++ +G Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 61 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ + +E +AF ++D+DGNGYI EL ++ +L EK Sbjct: 62 IDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEK 114 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + + DG Sbjct: 115 LTDE----EVDEMIREADIDGDG 133 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 31/72 (43%), Gaps = 6/72 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + E + FD DG+GY+ EL++++ L + E+ + + DG Sbjct: 80 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD------EEVDEMIREADIDGDG 133 Query: 72 KIGIVELAHVLP 83 ++ E ++ Sbjct: 134 QVNYEEFVQMMT 145 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 47/117 (40%), Gaps = 14/117 (11%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E ++ ARK + E++ + + +G Sbjct: 43 TEAELQDMINEVDADGNGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNG 97 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLK 128 I EL HV+ L + EE + R+ D D G + EE + Sbjct: 98 YISAAELRHVMTNLGEKL---------TDEEVDEMIREADIDGDGQVNYEEFVQMMT 145 Score = 31.3 bits (69), Expect = 0.46, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 Q + EF +AF L D+DG+G I EL +++ L + Sbjct: 2 QLTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQ 40 >1CLM-A nrPDB Length = 148 Score = 130 bits (326), Expect = 6e-31, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 22/162 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 9 IAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 62 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + ++ S EE ++ ++ +D D +G I EL++ + +L E Sbjct: 63 IDFPEFLSLMAR--------KMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGE 114 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 K + D M++ D + DG + E R++ + Sbjct: 115 KLTD--------DEVDEMIREADIDGDGHINYEEFVRMMVSK 148 Score = 98.0 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 32/143 (22%), Positives = 61/143 (42%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E L+ + + +E +AF+++D+DGNG I EL ++ +L EK Sbjct: 63 IDFPEFLSLMARKM-------KEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEK 115 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 L + + + DG Sbjct: 116 ----LTDDEVDEMIREADIDGDG 134 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 14/116 (12%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T ++ ++ DADG+G ++ E +L+ ARK + E+ + + +G Sbjct: 44 TEAELQDMINEVDADGNGTIDFPEFLSLM-----ARKMKEQDSEEELIEAFKVFDRDGNG 98 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 I EL HV+ L + +E + R+ D D G I EE + Sbjct: 99 LISAAELRHVMTNLGEKL---------TDDEVDEMIREADIDGDGHINYEEFVRMM 145 >4JWQ-A nrPDB Length = 199 Score = 128 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 22/169 (13%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 QS+ Q ++L+ D DG G + +L++ + +GL+L +DQ Sbjct: 51 QSNDYDLQQLKTVFLYLDEDGKGNITK-------NQLKKGLENSGLKLPQNFDVLLDQID 103 Query: 67 QRDDGKIGIVEL-AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 G+I E A L + L C +R +D D+ G I T EL + Sbjct: 104 SDGSGRIDYTEFLAAALDRKHLSKKLIYC-----------AFRVFDVDNDGEITTAELAH 152 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 L + +K + T D + M++ D NNDGK++ E ++ ++ Sbjct: 153 ILYNGNKKGSITQKDVNQVKK---MIQEVDKNNDGKIDFYEFCEMMKLK 198 Score = 80.6 bits (197), Expect = 5e-16, Method: Composition-based stats. Identities = 31/145 (21%), Positives = 57/145 (39%), Gaps = 19/145 (13%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 ++ + D D G I +LK L++ KL + D++L DS+ G Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQLKKGLENSGL---------KLPQNFDVLLDQIDSDGSG 108 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 +++ TE + K AF ++D D +G I EL +L + + Sbjct: 109 RIDYTEFLAA---------ALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNK 159 Query: 221 K-NKQDLDINNITTYKKNIMALSDG 244 K + D+N + + + +DG Sbjct: 160 KGSITQKDVNQVKKMIQEVDKNNDG 184 >3O4Y-A nrPDB Length = 196 Score = 127 bits (319), Expect = 4e-30, Method: Composition-based stats. Identities = 39/169 (23%), Positives = 69/169 (40%), Gaps = 22/169 (13%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 QS+ + +LH D +G G + +L++ +++GL L P +DQ Sbjct: 48 QSNDYDVQKLKAAFLHLDEEGKGNITKL-------QLRKGLERSGLMLPPNFDLLLDQID 100 Query: 67 QRDDGKIGIVEL-AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 G I E A + + L C +R +D D+ G I T EL + Sbjct: 101 SDGSGNIDYTEFLAAAIDRRQLSKKLIYC-----------AFRVFDVDNDGEITTAELAH 149 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 L + ++ N T D + M++ D N DGK++ E + ++ + Sbjct: 150 VLFNGNKRGNITERDVNQVKK---MIREVDKNGDGKIDFYEFSEMMKLT 195 Score = 78.3 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 61/173 (35%), Gaps = 20/173 (11%) Query: 74 GIVELAHVLPTEENFLLLFRCQQLK-SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 A +L ++ + + Q ++ + D + G I +L+ L+ Sbjct: 27 NFKNYALMLRFQKLAMTIIAQQSNDYDVQKLKAAFLHLDEEGKGNITKLQLRKGLERSGL 86 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 DL+L DS+ G ++ TE ++ K Sbjct: 87 MLPPNF---------DLLLDQIDSDGSGNIDYTEFLAA---------AIDRRQLSKKLIY 128 Query: 193 KAFELYDQDGNGYIDENELDALLKDLCEK-NKQDLDINNITTYKKNIMALSDG 244 AF ++D D +G I EL +L + ++ N + D+N + + + DG Sbjct: 129 CAFRVFDVDNDGEITTAELAHVLFNGNKRGNITERDVNQVKKMIREVDKNGDG 181 >3K21-A nrPDB Length = 191 Score = 125 bits (313), Expect = 2e-29, Method: Composition-based stats. Identities = 44/168 (26%), Positives = 71/168 (42%), Gaps = 22/168 (13%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 QS+ + +L D DG GY+ + +L++ +K GL+L +DQ Sbjct: 45 QSNDYDVEKLKSTFLVLDEDGKGYITKE-------QLKKGLEKDGLKLPYNFDLLLDQID 97 Query: 67 QRDDGKIGIVEL-AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 GKI E A L ++ L C +R +D D+ G I T EL + Sbjct: 98 SDGSGKIDYTEFIAAALDRKQLSKKLIYC-----------AFRVFDVDNDGEITTAELAH 146 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 L + +K N T D M++ D NNDGK++ E + ++ + Sbjct: 147 ILYNGNKKGNITQRDVN---RVKRMIRDVDKNNDGKIDFHEFSEMMKL 191 Score = 91.0 bits (224), Expect = 5e-19, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 61/145 (42%), Gaps = 19/145 (13%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E+ T+ D D G+I E+LK L+ D KL DL+L DS+ G Sbjct: 52 EKLKSTFLVLDEDGKGYITKEQLKKGLE---------KDGLKLPYNFDLLLDQIDSDGSG 102 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 K++ TE ++ K AF ++D D +G I EL +L + + Sbjct: 103 KIDYTEFIAA---------ALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNK 153 Query: 221 K-NKQDLDINNITTYKKNIMALSDG 244 K N D+N + +++ +DG Sbjct: 154 KGNITQRDVNRVKRMIRDVDKNNDG 178 >2L1W-A nrPDB Length = 149 Score = 118 bits (294), Expect = 4e-27, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 68/157 (43%), Gaps = 22/157 (14%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 F E + FD DG G + +EL +I+ L Q + E++ + + +G I Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE------EELQDMISEVDADGNGTIE 64 Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKA 134 E ++ + + + EE + ++ +D D +G+I EL++ + +L EK Sbjct: 65 FDEFLSLMAK--------KVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKL 116 Query: 135 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E + M+K D + DG++ E +++ Sbjct: 117 TD--------EEVEQMIKEADLDGDGQVNYEEFVKMM 145 Score = 88.7 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 +F + + +D D G I EEL ++ L + + E M+ D++ +G Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE--------EELQDMISEVDADGNGT 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E E L+ + +E +AF+++D+D NGYI +EL ++ +L EK Sbjct: 63 IEFDEFLSLMAKK-------VKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEK 115 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + + K DG Sbjct: 116 LTDE----EVEQMIKEADLDGDG 134 Score = 35.2 bits (79), Expect = 0.027, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 14/116 (12%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T + ++ DADG+G +E E +L+ + K + E+K + + +G Sbjct: 44 TEEELQDMISEVDADGNGTIEFDEFLSLMAK-----KVKDTDAEEELKEAFKVFDKDQNG 98 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 I EL HV+ + + EE + ++ D D G + EE + Sbjct: 99 YISASELRHVM---------INLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMM 145 >2LMV-A nrPDB Length = 148 Score = 117 bits (293), Expect = 5e-27, Method: Composition-based stats. Identities = 33/162 (20%), Positives = 73/162 (45%), Gaps = 22/162 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F + ++ FD +G+G + +EL L++ L Q +A E++ + + ++G+ Sbjct: 9 IAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEA------ELQDLIAEAENNNNGQ 62 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + E ++ + ++ + EE + ++ +D D GFI EL+ + +L E Sbjct: 63 LNFTEFCGIMAK--------QMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGE 114 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 K E D M++ D + DG + E ++ + Sbjct: 115 KVTD--------EEIDEMIREADFDGDGMINYEEFVWMISQK 148 Score = 93.0 bits (229), Expect = 1e-19, Method: Composition-based stats. Identities = 32/143 (22%), Positives = 62/143 (43%), Gaps = 19/143 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + ++D + +G I T EL ++ L + + ++ ++NN+G+ Sbjct: 11 EFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEA--------ELQDLIAEAENNNNGQ 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 L TE ++ Q +E +AF+++D+DG+G+I EL ++ +L EK Sbjct: 63 LNFTEFCGIMAKQMR-------ETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEK 115 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + I + DG Sbjct: 116 VTDE----EIDEMIREADFDGDG 134 >1TOP-A nrPDB Length = 162 Score = 117 bits (292), Expect = 6e-27, Method: Composition-based stats. Identities = 42/170 (24%), Positives = 76/170 (44%), Gaps = 21/170 (12%) Query: 2 AESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTF 61 A + L +I ++F + FDADG G + KEL +++ L Q K E+ Sbjct: 10 ARAFLSEEMI--AEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK------EELDAI 61 Query: 62 VDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETE 121 +++ + G I E ++ + + + KS EE +R +D + GFI+ E Sbjct: 62 IEEVDEDGSGTIDFEEFLVMMVRQ-----MKEDAKGKSEEELANCFRIFDKNADGFIDIE 116 Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 EL L+ E + E + ++K D NNDG+++ E +++ Sbjct: 117 ELGEILRATGEHVTE--------EDIEDLMKDSDKNNDGRIDFDEFLKMM 158 Score = 76.8 bits (187), Expect = 8e-15, Method: Composition-based stats. Identities = 32/143 (22%), Positives = 61/143 (42%), Gaps = 16/143 (11%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + +D D G I T+EL ++ L + K E D +++ D + G Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK--------EELDAIIEEVDEDGSGT 72 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ Q +K +E F ++D++ +G+ID EL +L+ E Sbjct: 73 IDFEEFLVMMVRQ----MKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEH 128 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 ++ +I K+ +DG Sbjct: 129 VTEE----DIEDLMKDSDKNNDG 147 >2TN4-A nrPDB Length = 159 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 21/170 (12%) Query: 2 AESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTF 61 A S+L +I ++F + FDADG G + KEL +++ L Q K E+ Sbjct: 7 ARSYLSEEMI--AEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTK------EELDAI 58 Query: 62 VDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETE 121 +++ + G I E ++ + + + KS EE + +R +D + G+I+ E Sbjct: 59 IEEVDEDGSGTIDFEEFLVMMVRQ-----MKEDAKGKSEEELAELFRIFDRNADGYIDAE 113 Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 EL + E E + ++K D NNDG+++ E +++ Sbjct: 114 ELAEIFRASGEHVTD--------EEIESLMKDGDKNNDGRIDFDEFLKMM 155 Score = 77.9 bits (190), Expect = 4e-15, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 59/143 (41%), Gaps = 16/143 (11%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + +D D G I +EL ++ L + K E D +++ D + G Sbjct: 18 EFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTK--------EELDAIIEEVDEDGSGT 69 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ E ++ Q +K +E + F ++D++ +GYID EL + + E Sbjct: 70 IDFEEFLVMMVRQ----MKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRASGEH 125 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 + I + K+ +DG Sbjct: 126 VTDE----EIESLMKDGDKNNDG 144 >5E37-A nrPDB Length = 356 Score = 113 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 13/179 (7%) Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV 138 V+P F L EE + ++ D D +G I+ EEL+N L+ + + Sbjct: 7 VRVVPRAATFEGLMDDASKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMM 66 Query: 139 DDTKLAE-YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFEL 197 L E + ++ +D N DG + E +++ ++ E+ AF+ Sbjct: 67 SQHWLPEDELERCMEQYDVNKDGVISFEEFKQII-------YDGLLLEGTLAEYESAFKA 119 Query: 198 YDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDLALIL 256 D+ GNG I EL L L + ++ + Y K+ D G++ + L+ Sbjct: 120 VDKSGNGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKD-----DSGQIEFPEFLLMF 173 Score = 73.3 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 66/167 (39%), Gaps = 19/167 (11%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLE---LSPEMKTFVD 63 +S + + D DG+G+++ +EL+NL++ ++ + E++ ++ Sbjct: 22 DASKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCME 81 Query: 64 QYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL 123 QY DG I E ++ + E+ ++ D +G I EL Sbjct: 82 QYDVNKDGVISFEEFKQIIYDGLLLEG--------TLAEYESAFKAVDKSGNGTIGATEL 133 Query: 124 KNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 L + L + DLM +++D ++ G++E E + Sbjct: 134 SKLFASLG-------NPVSLEKLVDLM-QMYDKDDSGQIEFPEFLLM 172 Score = 64.9 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 39/179 (21%), Positives = 74/179 (41%), Gaps = 21/179 (11%) Query: 56 PEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHS 115 E++ +G I EL ++L + E+ + Q +E + +YD + Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKD 88 Query: 116 GFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQE 175 G I EE K + D + + LAEY K D + +G + TE+++L Sbjct: 89 GVISFEEFKQIIYDG------LLLEGTLAEYESA-FKAVDKSGNGTIGATELSKLFA--- 138 Query: 176 NFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTY 234 G + ++ ++YD+D +G I+ E + ++ LD+ ++TTY Sbjct: 139 -----SLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRN------SLLDLKDMTTY 186 >3QRX-A nrPDB Length = 169 Score = 107 bits (266), Expect = 5e-24, Method: Composition-based stats. Identities = 40/164 (24%), Positives = 71/164 (43%), Gaps = 22/164 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FD DGSG ++ KEL+ ++ L KK E+K + + + G I Sbjct: 28 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK------EEIKKMISEIDKDGSGTI 81 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E ++ + + S EE +K +R +D D+SG I ++L+ K+L E Sbjct: 82 DFEEFLTMMTA--------KMGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGEN 133 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 + E M+ D N+D +++ E R++ F Sbjct: 134 LTE--------EELQEMIAEADRNDDNEIDEDEFIRIMKKTSLF 169 Score = 73.3 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 57/128 (44%), Gaps = 15/128 (11%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +DTD SG I+ +ELK ++ L + K E M+ D + Sbjct: 25 EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK--------EEIKKMISEIDKD 76 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 G ++ E ++ + G + +E KAF L+D D +G I +L + K+ Sbjct: 77 GSGTIDFEEFLTMMTAKM-------GERDSREEILKAFRLFDDDNSGTITIKDLRRVAKE 129 Query: 218 LCEKNKQD 225 L E ++ Sbjct: 130 LGENLTEE 137 Score = 44.4 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 35/184 (19%), Positives = 67/184 (36%), Gaps = 24/184 (13%) Query: 33 GKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLF 92 K + + ++ ++ R E E++ D + G I EL + + Sbjct: 5 AKTVVSARRDQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELK---------VAMR 55 Query: 93 RCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLK 152 EE K + D D SG I+ EE + + + E + Sbjct: 56 ALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMM-------TAKMGERDSREEILKAFR 108 Query: 153 LFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELD 212 LFD +N G + + ++ R+ K G + +E + D++ + IDE+E Sbjct: 109 LFDDDNSGTITIKDLRRV--------AKELGENLTEEELQEMIAEADRNDDNEIDEDEFI 160 Query: 213 ALLK 216 ++K Sbjct: 161 RIMK 164 Score = 34.0 bits (76), Expect = 0.060, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Query: 172 PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNI 231 ++ + + +E +AF+L+D DG+G ID EL ++ L + K++ I Sbjct: 11 ARRDQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKE----EI 66 Query: 232 TTYKKNIMALSDG 244 I G Sbjct: 67 KKMISEIDKDGSG 79 >2LHI-A nrPDB Length = 176 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 33/188 (17%), Positives = 75/188 (39%), Gaps = 23/188 (12%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD D +G + EL +++ L + +A E+ +++ + + Sbjct: 10 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA------EVNDLMNEIDVDGNHQ 63 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S +E ++ ++ +D + G I ELK+ L + E Sbjct: 64 IEFSEFLALMSR--------QLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 K D ML+ S+ G++ + + A LL + + + ++ Sbjct: 116 KLTDA--------EVDDMLREV-SDGSGEINIQQFAALLSKGSSTGTRRKALRNKILAIA 166 Query: 193 KAFELYDQ 200 K ++ Sbjct: 167 KVSRMFSV 174 Score = 91.4 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 23/161 (14%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D++G I + EL ++ L ++ + ++ D + + + Sbjct: 12 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA--------EVNDLMNEIDVDGNHQ 63 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q +E +AF+++D++G+G I EL +L + EK Sbjct: 64 IEFSEFLALMSRQLKSN-------DSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 116 Query: 222 NKQDLDINNITTYKKNIMALSDG-GKLYRTDLALILCAGDN 261 L + + + SDG G++ A +L G + Sbjct: 117 ----LTDAEVDDMLREV---SDGSGEINIQQFAALLSKGSS 150 >3KF9-A nrPDB Length = 149 Score = 99 bits (247), Expect = 8e-22, Method: Composition-based stats. Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 22/164 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FD DGSG ++ KEL+ ++ L KK E+K + + G I Sbjct: 8 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK------EEIKKMIADIDKDGSGTI 61 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E ++ + + S EE MK +R +D D +G I + LK K+L E Sbjct: 62 DFEEFLQMMTA--------KMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGEN 113 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 E M+ D + DG++ E R++ F Sbjct: 114 MTD--------EELQEMIDEADRDGDGEVNEEEFFRIMKKTSLF 149 Score = 67.5 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 15/123 (12%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +DTD SG I+ +ELK ++ L + K E M+ D + Sbjct: 5 EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK--------EEIKKMIADIDKD 56 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 G ++ E +++ + G + +E KAF L+D D G I L + K+ Sbjct: 57 GSGTIDFEEFLQMMTAKM-------GERDSREEIMKAFRLFDDDETGKISFKNLKRVAKE 109 Query: 218 LCE 220 L E Sbjct: 110 LGE 112 Score = 32.5 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 29/63 (46%), Gaps = 4/63 (6%) Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMAL 241 + +E +AF+L+D DG+G ID EL ++ L + K++ I +I Sbjct: 1 GLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKE----EIKKMIADIDKD 56 Query: 242 SDG 244 G Sbjct: 57 GSG 59 Score = 28.3 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 30/77 (38%), Gaps = 8/77 (10%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 + + LFD++ G ++ E+ + + G + +E K D+ Sbjct: 4 EEQKQEIREAFDLFDTDGSGTIDAKELKVAM--------RALGFEPKKEEIKKMIADIDK 55 Query: 201 DGNGYIDENELDALLKD 217 DG+G ID E ++ Sbjct: 56 DGSGTIDFEEFLQMMTA 72 >5D43-A nrPDB Length = 178 Score = 98.7 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 22/164 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FD+DGSG ++ KEL+ ++ L +K EMK + + + GKI Sbjct: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRK------EEMKKMISEVDKEATGKI 84 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 + V+ + + + EE +K +R +D D +G I + LK +L E Sbjct: 85 SFNDFLAVMTQ--------KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES 136 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 E M+ D + DG++ E +++ + Sbjct: 137 LTD--------EELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 Score = 64.1 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 32/147 (21%), Positives = 53/147 (36%), Gaps = 19/147 (12%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 +E + + +D+D SG I+ +ELK ++ L + K E M+ D Sbjct: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRK--------EEMKKMISEVDKE 79 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 GK+ + ++ + K +E KAF L+D D G I L + + Sbjct: 80 ATGKISFNDFLAVMTQKM-------AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 Query: 218 LCEKNKQDLDINNITTYKKNIMALSDG 244 L E L + DG Sbjct: 133 LGE----SLTDEELQEMIDEADRDGDG 155 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 34/81 (41%), Gaps = 6/81 (7%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 + T + + + FD D +G + K L+ + EL ++ E++ +D+ + Sbjct: 98 AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD------EELQEMIDEADR 151 Query: 68 RDDGKIGIVELAHVLPTEENF 88 DG++ E ++ + Sbjct: 152 DGDGEVNEEEFLKIMKKTNLY 172 Score = 32.5 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 4/65 (6%) Query: 180 KFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIM 239 K + + +E +AF+L+D DG+G ID EL ++ L + +++ + + Sbjct: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE----EMKKMISEVD 77 Query: 240 ALSDG 244 + G Sbjct: 78 KEATG 82 Score = 28.6 bits (62), Expect = 2.5, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 32/88 (36%), Gaps = 8/88 (9%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 + LFDS+ G +++ E+ + + G + +E K D+ Sbjct: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAM--------RALGFEPRKEEMKKMISEVDK 78 Query: 201 DGNGYIDENELDALLKDLCEKNKQDLDI 228 + G I N+ A++ + +I Sbjct: 79 EATGKISFNDFLAVMTQKMAEKDTKEEI 106 >4DS7-A nrPDB Length = 147 Score = 98.0 bits (242), Expect = 4e-21, Method: Composition-based stats. Identities = 33/161 (20%), Positives = 66/161 (40%), Gaps = 23/161 (14%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD D SG + EL +++ L + +A E+ +++ + Sbjct: 10 IAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEA------EVADLMNEIDVDGNHA 63 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S +E ++ ++ +D + G I ELK+ L + E Sbjct: 64 IEFSEFLALMSR--------QLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 K D ML+ S+ G++ + + A LL Sbjct: 116 KLTDA--------EVDEMLREV-SDGSGEINIKQFAALLSK 147 Score = 86.8 bits (213), Expect = 8e-18, Method: Composition-based stats. Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D+SG I EL ++ L ++ AE DLM D + + Sbjct: 12 EFKEAFALFDKDNSGSISASELATVMRSLGLSPSE-------AEVADLM-NEIDVDGNHA 63 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q +E +AF+++D++G+G I EL +L + EK Sbjct: 64 IEFSEFLALMSRQLKCN-------DSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 116 Score = 41.0 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 31/73 (42%), Gaps = 7/73 (9%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + E + FD +G G + EL++++ + + A E+ + + G Sbjct: 82 SEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDA------EVDEMLREV-SDGSG 134 Query: 72 KIGIVELAHVLPT 84 +I I + A +L Sbjct: 135 EINIKQFAALLSK 147 Score = 35.6 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 20/31 (64%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLC 219 EF +AF L+D+D +G I +EL +++ L Sbjct: 11 AEFKEAFALFDKDNSGSISASELATVMRSLG 41 >1LKJ-A nrPDB Length = 146 Score = 97.6 bits (241), Expect = 5e-21, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 67/161 (41%), Gaps = 23/161 (14%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD D +G + EL +++ L + +A E+ +++ + + Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA------EVNDLMNEIDVDGNHQ 62 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S +E ++ ++ +D + G I ELK+ L + E Sbjct: 63 IEFSEFLALMSR--------QLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 114 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 K D ML+ S+ G++ + + A LL Sbjct: 115 KLTDA--------EVDDMLREV-SDGSGEINIQQFAALLSK 146 Score = 86.4 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D++G I + EL ++ L ++ + ++ D + + + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA--------EVNDLMNEIDVDGNHQ 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q +E +AF+++D++G+G I EL +L + EK Sbjct: 63 IEFSEFLALMSRQLKSN-------DSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 115 >2GGM-A nrPDB Length = 172 Score = 97.6 bits (241), Expect = 5e-21, Method: Composition-based stats. Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 22/164 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FDADG+G ++ KEL+ ++ L KK E+K + + + GK+ Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK------EEIKKMISEIDKEGTGKM 84 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 + V+ + + + EE +K ++ +D D +G I + LK K+L E Sbjct: 85 NFGDFLTVMTQ--------KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGEN 136 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 E M+ D + DG++ E R++ + Sbjct: 137 LTD--------EELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172 Score = 62.2 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 15/123 (12%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +D D +G I+ +ELK ++ L + K E M+ D Sbjct: 28 EQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK--------EEIKKMISEIDKE 79 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 GK+ + ++ + + K +E KAF+L+D D G I L + K+ Sbjct: 80 GTGKMNFGDFLTVMTQKMS-------EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKE 132 Query: 218 LCE 220 L E Sbjct: 133 LGE 135 Score = 40.6 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 34/81 (41%), Gaps = 6/81 (7%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 S T + + + FD D +G + K L+ + +EL + E++ +D+ + Sbjct: 98 SEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD------EELQEMIDEADR 151 Query: 68 RDDGKIGIVELAHVLPTEENF 88 DG++ E ++ + Sbjct: 152 DGDGEVSEQEFLRIMKKTSLY 172 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Query: 172 PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNI 231 ++ K + + +E +AF+L+D DG G ID EL ++ L + K++ I Sbjct: 14 SQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKE----EI 69 Query: 232 TTYKKNIMALSDG 244 I G Sbjct: 70 KKMISEIDKEGTG 82 >2LAP-A nrPDB Length = 167 Score = 92.6 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 64/162 (39%), Gaps = 17/162 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + E + FD D GY+ ++L N ++ + + E+ Q G Sbjct: 23 EIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEM------ELIELSQQINMNLGG 76 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 + + ++ + LL + +E +R++DT+ G I T EL+ ++ LL Sbjct: 77 HVDFDDFVELMGPK----LLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLL 132 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 D + +++ D N DG+++ E R++ Sbjct: 133 GHQVGHRD-------IEEIIRDVDLNGDGRVDFEEFVRMMSR 167 Score = 74.1 bits (180), Expect = 6e-14, Method: Composition-based stats. Identities = 30/144 (20%), Positives = 58/144 (40%), Gaps = 14/144 (9%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EE + +R++D D G+I +L N ++ + + + + + N G Sbjct: 25 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEM--------ELIELSQQINMNLGG 76 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ + L+ + LL + KE AF +D +G+G I +EL ++ L Sbjct: 77 HVDFDDFVELMGPK---LLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLG 133 Query: 221 KNKQDLDINNITTYKKNIMALSDG 244 DI I +++ DG Sbjct: 134 HQVGHRDIEEI---IRDVDLNGDG 154 Score = 48.7 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 30/78 (38%), Gaps = 5/78 (6%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + +I + + + FD +G G + EL+ +++L +++ + Sbjct: 95 TADMIGVKELRDAFREFDTNGDGEISTSELREAMRKL-----LGHQVGHRDIEEIIRDVD 149 Query: 67 QRDDGKIGIVELAHVLPT 84 DG++ E ++ Sbjct: 150 LNGDGRVDFEEFVRMMSR 167 >5T7C-A nrPDB Length = 193 Score = 92.2 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 61/155 (39%), Gaps = 24/155 (15%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + E + ++ + D +G + +E K + +++ + + + FD+N Sbjct: 23 TDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYG-------DASKFAEHVFRTFDTN 75 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 DG ++ E L V L+ ++ AF +YD DGNGYI +E+ +++ Sbjct: 76 GDGTIDFREFIIALSVTSRGKLE--------QKLKWAFSMYDLDGNGYISRSEMLEIVQA 127 Query: 218 LCEKNKQDLDI--------NNITTYKKNIMALSDG 244 + + + + + + +DG Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDG 162 Score = 61.8 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 50/131 (38%), Gaps = 13/131 (9%) Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + DG I E L + K ++ + YD D +G+I E+ Sbjct: 72 FDTNGDGTIDFREFIIALS---------VTSRGKLEQKLKWAFSMYDLDGNGYISRSEML 122 Query: 125 NFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 180 ++ + + + + D++ + TD + + D+NNDGKL L E R + + Sbjct: 123 EIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRL 182 Query: 181 FQGIKMCGKEF 191 Q +F Sbjct: 183 LQCDPSSASQF 193 Score = 47.9 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 50/116 (43%), Gaps = 10/116 (8%) Query: 12 TASQFFE-IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 AS+F E ++ FD +G G ++ +E + + +L ++K Y + Sbjct: 60 DASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRG------KLEQKLKWAFSMYDLDGN 113 Query: 71 GKIGIVELAHVLPT-EENFLLLFRCQQLKSCEEFM--KTWRKYDTDHSGFIETEEL 123 G I E+ ++ + + + + +S E K +R+ DT++ G + EE Sbjct: 114 GYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEF 169 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 27/176 (15%), Positives = 61/176 (34%), Gaps = 23/176 (13%) Query: 39 LIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLK 98 ++Q+L++ + EL K F+ G + + E + + Sbjct: 12 VLQDLRENTEFTDHELQEWYKGFLKDC---PTGHLTVDEFKKIYANFFPY--------GD 60 Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 + + +R +DT+ G I+ E L KL + ++D + Sbjct: 61 ASKFAEHVFRTFDTNGDGTIDFREFIIAL--------SVTSRGKLEQKLKWAFSMYDLDG 112 Query: 159 DGKLELTEMARLL----PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 +G + +EM ++ + + + + K +K F D + +G + E Sbjct: 113 NGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEE 168 Score = 37.9 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 35/94 (37%), Gaps = 6/94 (6%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQ------ARKKAGLELSPEMKTFVDQYGQ 67 + + +D DG+GY+ E+ ++Q + + + Q Sbjct: 99 QKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDT 158 Query: 68 RDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCE 101 +DGK+ + E ++ + + L +C + + Sbjct: 159 NNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQ 192 >2LC5-A nrPDB Length = 151 Score = 91.8 bits (226), Expect = 3e-19, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 16/132 (12%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 + +E+ + ++ +D D+ + EEL ++ L K + ++K +D Sbjct: 10 AEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTK--------QKISEIVKDYDK 61 Query: 157 NNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 +N GK + ++ L++ ++ KAFE++D++ NGYI +EL +L Sbjct: 62 DNSGKFDQETFLTIM-------LEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLT 114 Query: 217 DLCEK-NKQDLD 227 L EK +Q++D Sbjct: 115 TLGEKLTEQEVD 126 Score = 82.6 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 33/161 (20%), Positives = 63/161 (39%), Gaps = 23/161 (14%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++ E + FD D L +EL +++ L K ++ V Y + + GK Sbjct: 14 QEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTK------QKISEIVKDYDKDNSGKF 67 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 ++ L Q++ S E+ K + +D + +G+I ELK+ L L EK Sbjct: 68 DQETFLTIM--------LEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTLGEK 119 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 + D L E +G + + + +L+ + Sbjct: 120 LTEQEVDDLLKEIGVE---------EGLINVDDFVKLITSK 151 Score = 34.4 bits (77), Expect = 0.051, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 4/76 (5%) Query: 184 IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 +E+ +AF+L+D+D + + EL +++ L + I+ K+ + Sbjct: 9 TAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQ----KISEIVKDYDKDNS 64 Query: 244 GGKLYRTDLALILCAG 259 G T L ++L G Sbjct: 65 GKFDQETFLTIMLEYG 80 Score = 33.6 bits (75), Expect = 0.090, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + + FD + +GY+ EL++++ L + + E+ + + G ++G Sbjct: 85 STEDIKKAFEIFDKEKNGYISASELKHVLTTLGEKLTE------QEVDDLLKEIG-VEEG 137 Query: 72 KIGIVELAHVLPTE 85 I + + ++ ++ Sbjct: 138 LINVDDFVKLITSK 151 >1BJF-A nrPDB Length = 193 Score = 91.0 bits (224), Expect = 4e-19, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 60/155 (38%), Gaps = 24/155 (15%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + E + ++ + D SG + EE K + +++ + + + FD+N Sbjct: 23 TEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYG-------DASKFAEHVFRTFDAN 75 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 DG ++ E L V L+ ++ AF +YD DGNGYI + E+ +++ Sbjct: 76 GDGTIDFREFIIALSVTSRGKLE--------QKLKWAFSMYDLDGNGYISKAEMLEIVQA 127 Query: 218 LCEKNKQDLDI--------NNITTYKKNIMALSDG 244 + + + + + + DG Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDG 162 Score = 60.2 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 33/169 (19%), Positives = 64/169 (37%), Gaps = 19/169 (11%) Query: 6 LQSSLITASQFFEIWLHFDAD-GSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQ 64 L+S+ T + E + F D SG+L +E + + + + Sbjct: 17 LESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFA-----EHVFRT 71 Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + DG I E L + K ++ + YD D +G+I E+ Sbjct: 72 FDANGDGTIDFREFIIALS---------VTSRGKLEQKLKWAFSMYDLDGNGYISKAEML 122 Query: 125 NFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 ++ + + + + D++ + T+ + + D+N DGKL L E R Sbjct: 123 EIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIR 171 >1DTL-A nrPDB Length = 161 Score = 90.7 bits (223), Expect = 5e-19, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 64/159 (40%), Gaps = 20/159 (12%) Query: 15 QFFEIWLHFD-ADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 +F + F G + KEL +++ L Q E++ +D+ + G + Sbjct: 19 EFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPT------PEELQEMIDEVDEDGSGTV 72 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E ++ + + KS EE +R +D + G+I+ EELK L+ E Sbjct: 73 DFDEFLVMMVRS-----MKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGET 127 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 + + + ++K D NNDG+++ E + Sbjct: 128 ITE--------DDIEELMKDGDKNNDGRIDYDEFLEFMK 158 Score = 63.3 bits (152), Expect = 9e-11, Method: Composition-based stats. Identities = 30/144 (20%), Positives = 56/144 (38%), Gaps = 17/144 (11%) Query: 102 EFMKTWRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EF + + G I T+EL ++ L + E M+ D + G Sbjct: 19 EFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPT--------PEELQEMIDEVDEDGSG 70 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ E ++ +K +E + F ++D++ +GYID EL +L+ E Sbjct: 71 TVDFDEFLVMMVRS----MKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGE 126 Query: 221 KNKQDLDINNITTYKKNIMALSDG 244 +D +I K+ +DG Sbjct: 127 TITED----DIEELMKDGDKNNDG 146 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 12/135 (8%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 141 + T+E ++ Q + EE + + D D SG ++ +E + ++ K Sbjct: 36 ISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMM----VRSMKDDSKG 91 Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 K E + ++FD N DG ++L E+ +L G + + + + D++ Sbjct: 92 KSEEELSDLFRMFDKNADGYIDLEELKIMLQAT--------GETITEDDIEELMKDGDKN 143 Query: 202 GNGYIDENELDALLK 216 +G ID +E +K Sbjct: 144 NDGRIDYDEFLEFMK 158 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + +++ FD + GY++ +EL+ ++Q + + +++ + + +DG+I Sbjct: 96 ELSDLFRMFDKNADGYIDLEELKIMLQATGETITED------DIEELMKDGDKNNDGRID 149 Query: 75 IVELAHVLPTEE 86 E + E Sbjct: 150 YDEFLEFMKGVE 161 Score = 37.1 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 46/117 (39%), Gaps = 11/117 (9%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T + E+ D DGSG ++ E ++ + K E E+ + + DG Sbjct: 53 TPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKSE--EELSDLFRMFDKNADG 110 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLK 128 I + EL +L + + ++ + + D ++ G I+ +E F+K Sbjct: 111 YIDLEELKIMLQAT---------GETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK 158 >2OBH-A nrPDB Length = 143 Score = 90.3 bits (222), Expect = 7e-19, Method: Composition-based stats. Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 22/160 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FDADG+G ++ KEL+ ++ L KK E+K + + + GK+ Sbjct: 6 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK------EEIKKMISEIDKEGTGKM 59 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 + V+ + + + EE +K ++ +D D +G I + LK K+L E Sbjct: 60 NFGDFLTVMTQ--------KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGEN 111 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 E M+ D + DG++ E R++ Sbjct: 112 LTD--------EELQEMIDEADRDGDGEVSEQEFLRIMKK 143 Score = 58.7 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 15/123 (12%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +D D +G I+ +ELK ++ L + K E M+ D Sbjct: 3 EQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK--------EEIKKMISEIDKE 54 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 GK+ + ++ + + K +E KAF+L+D D G I L + K+ Sbjct: 55 GTGKMNFGDFLTVMTQKMS-------EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKE 107 Query: 218 LCE 220 L E Sbjct: 108 LGE 110 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 33/77 (42%), Gaps = 6/77 (7%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 S T + + + FD D +G + K L+ + +EL + E++ +D+ + Sbjct: 73 SEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD------EELQEMIDEADR 126 Query: 68 RDDGKIGIVELAHVLPT 84 DG++ E ++ Sbjct: 127 DGDGEVSEQEFLRIMKK 143 Score = 30.2 bits (66), Expect = 0.91, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 184 IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 + +E +AF+L+D DG G ID EL ++ L + K++ I I Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKE----EIKKMISEIDKEGT 56 Query: 244 G 244 G Sbjct: 57 G 57 >2LHH-A nrPDB Length = 128 Score = 88.3 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 14/124 (11%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD D +G + EL +++ L + +A E+ +++ + + Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA------EVNDLMNEIDVDGNHQ 62 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ + + S +E ++ ++ +D + G I ELK+ L + E Sbjct: 63 IEFSEFLALMSR--------QLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 114 Query: 133 KANK 136 K Sbjct: 115 KLTD 118 Score = 85.3 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 15/120 (12%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D++G I + EL ++ L ++ + ++ D + + + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA--------EVNDLMNEIDVDGNHQ 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E +E L+ Q +E +AF+++D++G+G I EL +L + EK Sbjct: 63 IEFSEFLALMSRQLKSN-------DSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEK 115 Score = 35.2 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 21/42 (50%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLE 53 + + E + FD +G G + EL++++ + + A LE Sbjct: 81 SEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAELE 122 >2R2I-A nrPDB Length = 198 Score = 87.6 bits (215), Expect = 6e-18, Method: Composition-based stats. Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 22/159 (13%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNF--LKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 S E + ++K+ T+ SG + E K F LK+L AN +Y + M + FD Sbjct: 12 SATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSAN---------KYVEQMFETFD 62 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 N DG ++ E L + + ++ F+LYD DGNG ID EL ++ Sbjct: 63 FNKDGYIDFMEYVAALSLVLKGKVD--------QKLRWYFKLYDVDGNGCIDRGELLNII 114 Query: 216 KDLCEKNK--QDLDINNITTYKKNIMALSDGGKLYRTDL 252 K + N+ + + T + + ++ G+L + Sbjct: 115 KAIRAINRCNEAMTAEEFTNMVFDKIDINGDGELSLEEF 153 Score = 52.1 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 50/131 (38%), Gaps = 10/131 (7%) Query: 45 QARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFM 104 K + ++ + + DG I +E L + K ++ Sbjct: 41 FGLKNLSPSANKYVEQMFETFDFNKDGYIDFMEYVAALSL---------VLKGKVDQKLR 91 Query: 105 KTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 164 ++ YD D +G I+ EL N +K + N+ + E+T+++ D N DG+L L Sbjct: 92 WYFKLYDVDGNGCIDRGELLNIIKAI-RAINRCNEAMTAEEFTNMVFDKIDINGDGELSL 150 Query: 165 TEMARLLPVQE 175 E + E Sbjct: 151 EEFMEGVQKDE 161 Score = 42.1 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV-DQYGQRDDGKIGIVEL 78 + +D DG+G ++ EL N+I+ ++ + + E V D+ DG++ + E Sbjct: 94 FKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGELSLEEF 153 Query: 79 AHVLPTEENFLLLFRC 94 + +E L + Sbjct: 154 MEGVQKDEVLLDILTR 169 >3HZT-A nrPDB Length = 467 Score = 86.8 bits (213), Expect = 8e-18, Method: Composition-based stats. Identities = 41/180 (22%), Positives = 71/180 (39%), Gaps = 27/180 (15%) Query: 2 AESHLQSSLITASQFFE---IWLHFDADGSGYLEGKELQNLIQELQQ--ARKKAGL---E 53 A + S L T + E I+ D +G G L+ KEL ++L Q + L + Sbjct: 299 AMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQ 358 Query: 54 LSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTD 113 + E+ + +G I E V ++ L S E + ++++D+D Sbjct: 359 IEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLL---------SRERLLAAFQQFDSD 409 Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 SG I EEL + D+T +L+ D NNDG+++ E ++ Sbjct: 410 GSGKITNEELGRLF-----GVTEVDDETW-----HQVLQECDKNNDGEVDFEEFVEMMQK 459 Score = 67.2 bits (162), Expect = 6e-12, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 66/166 (39%), Gaps = 17/166 (10%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 141 L + + L+ +E + +R+ D + G ++ +EL + L++ TV D Sbjct: 295 LAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDL 354 Query: 142 KLAE---YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELY 198 ++ D +L+ D + +G +E +E + ++ + + + AF+ + Sbjct: 355 DSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQ--------LLLSRERLLAAFQQF 406 Query: 199 DQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 D DG+G I EL L ++D + +DG Sbjct: 407 DSDGSGKITNEELGRLF------GVTEVDDETWHQVLQECDKNNDG 446 >5JN2-A nrPDB Length = 525 Score = 86.0 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 35/162 (21%), Positives = 60/162 (37%), Gaps = 24/162 (14%) Query: 15 QFFEIWLHFDADGSGYLEGKEL----QNLIQELQQARKKAGLE-LSPEMKTFVDQYGQRD 69 + I+ D +G G L+ EL + L++ Q + E+ +D Sbjct: 377 ELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDK 436 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 +G I E V + L S E + +R +D+D+SG I + EL Sbjct: 437 NGYIEYSEFVTV---------AMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFG- 486 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +E +L D NNDG+++ E ++L Sbjct: 487 ---------VSDVDSETWKSVLSEVDKNNDGEVDFDEFQQML 519 Score = 74.9 bits (182), Expect = 4e-14, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 61/167 (36%), Gaps = 19/167 (11%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL----KNFLKDLLEKANKT 137 L + + +E + K D + G ++ EL K ++ + A+ Sbjct: 357 LAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDAS-M 415 Query: 138 VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFEL 197 +D + + D +L D + +G +E +E + ++ L + +AF + Sbjct: 416 LDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLL--------SRERLERAFRM 467 Query: 198 YDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +D D +G I EL + D+D + + +DG Sbjct: 468 FDSDNSGKISSTELATIF------GVSDVDSETWKSVLSEVDKNNDG 508 >3LIJ-A nrPDB Length = 494 Score = 84.5 bits (207), Expect = 4e-17, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 64/162 (39%), Gaps = 23/162 (14%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSP---EMKTFVDQYGQRDDG 71 + +I+ H D +G G L+ +EL + +L + A +L E+ + +G Sbjct: 347 ELTDIFRHIDKNGDGQLDRQELIDGYSKL-SGEEVAVFDLPQIESEVDAILGAADFDRNG 405 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I E V + L S ++ ++K+D D +G I +EL + Sbjct: 406 YIDYSEFVTV---------AMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG--- 453 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 D ++ M+ DSNNDG ++ E +++ Sbjct: 454 -------LDHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 488 Score = 72.6 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 62/163 (38%), Gaps = 14/163 (8%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 141 L + + + +E +R D + G ++ +EL + L + D Sbjct: 327 LAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLP 386 Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 ++ D +L D + +G ++ +E + +++ L + AF+ +DQD Sbjct: 387 QIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLL--------SKDKLESAFQKFDQD 438 Query: 202 GNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 GNG I +EL ++ L+ I + +DG Sbjct: 439 GNGKISVDELASVF------GLDHLESKTWKEMISGIDSNNDG 475 Score = 43.7 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 8/78 (10%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + SL++ + + FD DG+G + EL ++ S K + Sbjct: 419 RKSLLSKDKLESAFQKFDQDGNGKISVDELASVF--------GLDHLESKTWKEMISGID 470 Query: 67 QRDDGKIGIVELAHVLPT 84 +DG + E ++ Sbjct: 471 SNNDGDVDFEEFCKMIQK 488 >5M6C-E nrPDB Length = 193 Score = 84.1 bits (206), Expect = 6e-17, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 61/155 (39%), Gaps = 24/155 (15%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 S E + ++ + D +G + +E K + +++ + + + FD+N Sbjct: 23 SELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYG-------DASKFAEHVFRNFDTN 75 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 +DG ++ E L V L+ ++ AF +YD DGNGYI E+ +++ Sbjct: 76 SDGTIDFREFIIALSVTSRGRLE--------QKLMWAFSMYDLDGNGYISREEMLEIVQA 127 Query: 218 LCEKNKQDLDI--------NNITTYKKNIMALSDG 244 + + + + + + +DG Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDG 162 Score = 59.1 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 51/131 (38%), Gaps = 13/131 (9%) Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + DG I E L L ++ M + YD D +G+I EE+ Sbjct: 72 FDTNSDGTIDFREFIIALSVTSRGRL---------EQKLMWAFSMYDLDGNGYISREEML 122 Query: 125 NFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 180 ++ + + + + D++ + T+ + + D+NNDGKL L E R + + Sbjct: 123 EIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRL 182 Query: 181 FQGIKMCGKEF 191 Q +F Sbjct: 183 LQCDPSSTSQF 193 Score = 44.4 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 12 TASQFFE-IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 AS+F E ++ +FD + G ++ +E + + L ++ Y + Sbjct: 60 DASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRG------RLEQKLMWAFSMYDLDGN 113 Query: 71 GKIGIVELAHVLPT-EENFLLLFRCQQLKSCEE--FMKTWRKYDTDHSGFIETEEL 123 G I E+ ++ + + + + +S E K +R+ DT++ G + EE Sbjct: 114 GYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEF 169 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 27/176 (15%), Positives = 61/176 (34%), Gaps = 23/176 (13%) Query: 39 LIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLK 98 ++Q+L++ + + LEL K F+ G + + E + + Sbjct: 12 MLQDLRENTEFSELELQEWYKGFLKDC---PTGILNVDEFKKIYANFFPY--------GD 60 Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 + + +R +DT+ G I+ E L +L + ++D + Sbjct: 61 ASKFAEHVFRNFDTNSDGTIDFREFIIAL--------SVTSRGRLEQKLMWAFSMYDLDG 112 Query: 159 DGKLELTEMARLL----PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 +G + EM ++ + + + + K K F D + +G + E Sbjct: 113 NGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEE 168 Score = 36.0 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 36/89 (40%), Gaps = 6/89 (6%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQ------ARKKAGLELSPEMKTFVDQYGQRDDGK 72 + +D DG+GY+ +E+ ++Q + + + + Q +DGK Sbjct: 104 AFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGK 163 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCE 101 + + E ++ + + L +C + + Sbjct: 164 LSLEEFIRGAKSDPSIVRLLQCDPSSTSQ 192 >4MVF-A nrPDB Length = 506 Score = 84.1 bits (206), Expect = 6e-17, Method: Composition-based stats. Identities = 28/166 (16%), Positives = 66/166 (39%), Gaps = 21/166 (12%) Query: 10 LITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 + + I++ D D SG L +E+ + ++++ ++ P++ + Sbjct: 356 DVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQ------KIPPDIHQVLRDIDSNA 409 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 G+I + ++ +L E + ++ +D D +G I EELK Sbjct: 410 SGQIHYTDFLAATIDKQTYL---------KKEVCLIPFKFFDIDGNGKISVEELKRIF-- 458 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQE 175 +++ + + D +L+ D N DG+++ E ++ E Sbjct: 459 ----GRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKLE 500 Score = 55.2 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 55/142 (38%), Gaps = 18/142 (12%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 + D D+SG + ++E+ + LK + K+ +L+ DSN G++ Sbjct: 362 LRNIFIALDVDNSGTLSSQEILDGLKKIG--------YQKIPPDIHQVLRDIDSNASGQI 413 Query: 163 ELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKN 222 T+ ++ +L K + F+ +D DGNG I EL + + Sbjct: 414 HYTDFLAATIDKQTYLKKEVCLIP--------FKFFDIDGNGKISVEELKRIF--GRDDI 463 Query: 223 KQDLDINNITTYKKNIMALSDG 244 + L I + + + DG Sbjct: 464 ENPLIDKAIDSLLQEVDLNGDG 485 >2LCP-A nrPDB Length = 190 Score = 82.2 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 63/162 (38%), Gaps = 24/162 (14%) Query: 92 FRCQQLKSCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLM 150 + + +E + ++ + D SG ++ + K + T ++ + Sbjct: 16 LTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPT-------KFATFV 68 Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 +FD N DG++E +E + L V L ++ AF+LYD D +GYI NE Sbjct: 69 FNVFDENKDGRIEFSEFIQALSVTSRGTLD--------EKLRWAFKLYDLDNDGYITRNE 120 Query: 211 LDALLKDLCEKNKQDLDI--------NNITTYKKNIMALSDG 244 + ++ + + +++ + + +DG Sbjct: 121 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADG 162 Score = 49.4 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 43/109 (39%), Gaps = 13/109 (11%) Query: 63 DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEE 122 + + + DG+I E L L E+ ++ YD D+ G+I E Sbjct: 70 NVFDENKDGRIEFSEFIQALSVTSRGTL---------DEKLRWAFKLYDLDNDGYITRNE 120 Query: 123 LKNFLKDLLEKANKTV----DDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 + + + + + TV ++ + D + + D N DGKL L E Sbjct: 121 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEF 169 Score = 32.1 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 14/110 (12%), Positives = 38/110 (34%), Gaps = 9/110 (8%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 ++ FD + G +E E + + L + ++ Y +DG I E+ Sbjct: 68 VFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKL------YDLDNDGYITRNEM 121 Query: 79 AHVLPTEENFL---LLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 ++ + + ++ + + + D + G + +E + Sbjct: 122 LDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQE 171 >1S6I-A nrPDB Length = 188 Score = 82.2 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 37/197 (18%), Positives = 70/197 (35%), Gaps = 25/197 (12%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 E++ D D SG + EL++ ++ + ++ E+K +D G Sbjct: 8 EIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMES------EIKDLMDAADIDKSG 61 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I E +L+ E + + +D D SG+I +E++ KD Sbjct: 62 TIDYGEFIAA---------TVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFG 112 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEF 191 + D M+K D +NDG+++ E A ++ ++ + Sbjct: 113 LDDI----------HIDDMIKEIDQDNDGQIDYGEFAAMMRKRKGNGGIGRRTMRKTLNL 162 Query: 192 NKAFELYDQDGNGYIDE 208 A L D N I+ Sbjct: 163 RDALGLVDNGSNQVIEG 179 Score = 60.6 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 35/153 (22%), Positives = 59/153 (38%), Gaps = 25/153 (16%) Query: 95 QQLKSCEE---FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 151 + S EE + ++ DTD+SG I +ELK+ LK + + ++ ++ Sbjct: 1 AERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMES--------EIKDLM 52 Query: 152 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 D + G ++ E + AF +D+DG+GYI +E+ Sbjct: 53 DAADIDKSGTIDYGEFIAA--------TVHLNKLEREENLVSAFSYFDKDGSGYITLDEI 104 Query: 212 DALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 KD LD +I K I +DG Sbjct: 105 QQACKDFG------LDDIHIDDMIKEIDQDNDG 131 >3FWC-A nrPDB Length = 161 Score = 80.6 bits (197), Expect = 6e-16, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 62/157 (39%), Gaps = 22/157 (14%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + +E + FD + G+L+ EL+ ++ L K E+ +D+Y + Sbjct: 23 QEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPK------REILDLIDEYDSEGRHLM 76 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 + V+ + + +E + ++ +D DH+G I + L+ K+L E Sbjct: 77 KYDDFYIVMGEKIL--------KRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGET 128 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 E M++ FD + DG++ E + Sbjct: 129 LTD--------EELRAMIEEFDLDGDGEINENEFIAI 157 Score = 50.2 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 26/158 (16%), Positives = 56/158 (35%), Gaps = 19/158 (12%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +D ++ GF++ ELK +K L ++ +DS Sbjct: 20 EQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALG--------FELPKREILDLIDEYDSE 71 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 ++ + ++ + + E +AF+L+D D G I L + K+ Sbjct: 72 GRHLMKYDDFYIVMGEK-------ILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKE 124 Query: 218 LCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDLALI 255 L E + + + DG +A+ Sbjct: 125 LGETLTDE----ELRAMIEEFDLDGDGEINENEFIAIC 158 Score = 32.5 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 26/45 (57%) Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 ++ L + ++ +E +AF L+D + +G++D +EL +K L Sbjct: 9 QSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALG 53 >6EPA-A nrPDB Length = 187 Score = 80.3 bits (196), Expect = 7e-16, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 60/146 (41%), Gaps = 16/146 (10%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + + D +G + + K D +++ L+ ++FD N Sbjct: 23 TEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFP-------DGDPSKFASLVFRVFDEN 75 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 NDG +E E R L + L ++ + AF LYD D +GYI E+ ++ Sbjct: 76 NDGAIEFEEFIRALSITSRGNLD--------EKLHWAFRLYDVDNDGYITREEMYNIVDA 127 Query: 218 LCEKNKQDLDINNITTYKKNIMALSD 243 + + Q + T +K + + D Sbjct: 128 IYQMVGQQPQTEDENTPQKRVDKIFD 153 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 43/106 (40%), Gaps = 12/106 (11%) Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + + +DG I E L + E+ +R YD D+ G+I EE+ Sbjct: 72 FDENNDGAIEFEEFIRALSITS---------RGNLDEKLHWAFRLYDVDNDGYITREEMY 122 Query: 125 NFLKDLLE---KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 N + + + + +T D+ + D + D N+D +L L E Sbjct: 123 NIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEF 168 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 41/109 (37%), Gaps = 11/109 (10%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 +R +D ++ G IE EE L L E +L+D +NDG + E Sbjct: 69 FRVFDENNDGAIEFEEFIRAL--------SITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 Query: 167 MARLLPVQENFLLKFQGIKMC---GKEFNKAFELYDQDGNGYIDENELD 212 M ++ + + + K +K F+ D++ + + E Sbjct: 121 MYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFR 169 Score = 34.8 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 27/67 (40%), Gaps = 5/67 (7%) Query: 19 IWLHFDADGSGYLEGKELQNLI----QELQQARKKAGLELSPE-MKTFVDQYGQRDDGKI 73 + +D D GY+ +E+ N++ Q + Q + + + DQ + D ++ Sbjct: 104 AFRLYDVDNDGYITREEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRL 163 Query: 74 GIVELAH 80 + E Sbjct: 164 TLEEFRE 170 Score = 29.4 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 16/109 (14%), Positives = 40/109 (36%), Gaps = 8/109 (7%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 ++ FD + G +E +E + + L + + Y +DG I E+ Sbjct: 68 VFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRL------YDVDNDGYITREEM 121 Query: 79 AHVLPTEENFLLLFRCQQLKSCEE--FMKTWRKYDTDHSGFIETEELKN 125 +++ + + ++ + K + + D +H + EE + Sbjct: 122 YNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFRE 170 >2M29-A nrPDB Length = 171 Score = 79.9 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 53/156 (33%), Gaps = 17/156 (10%) Query: 17 FEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIV 76 + FD D GY+ +EL + ++ L + L + R G + Sbjct: 31 QAAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKM------RMGGFVDFE 84 Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 E ++ + E +R++D D G I EL+ LL + + Sbjct: 85 EFVELISPKLREETAHMLGVR----ELRIAFREFDKDRDGRITVAELRQAAPALLGEPLE 140 Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 D ML+ D N DG ++ E +L Sbjct: 141 GT-------ELDEMLREMDLNGDGTIDFDEFVMMLS 169 Score = 63.3 bits (152), Expect = 9e-11, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 54/154 (35%), Gaps = 15/154 (9%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 165 + ++DTD G+I EL + ++ L + M G ++ Sbjct: 33 AFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRM--------GGFVDFE 84 Query: 166 EMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQD 225 E L+ + + + +E AF +D+D +G I EL L + Sbjct: 85 EFVELISPKLR---EETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLG---EP 138 Query: 226 LDINNITTYKKNIMALSDGGKLYRTDLALILCAG 259 L+ + + + D G + + ++L G Sbjct: 139 LEGTELDEMLREMDLNGD-GTIDFDEFVMMLSTG 171 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 26/78 (33%), Gaps = 5/78 (6%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + ++ + + FD D G + EL+ L + E+ + + Sbjct: 98 TAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEG-----TELDEMLREMD 152 Query: 67 QRDDGKIGIVELAHVLPT 84 DG I E +L T Sbjct: 153 LNGDGTIDFDEFVMMLST 170 >3PM8-A nrPDB Length = 197 Score = 79.5 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 66/165 (40%), Gaps = 21/165 (12%) Query: 10 LITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 + + I++ D D SG L +E+ + ++++ ++ P++ + Sbjct: 53 DVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQ------KIPPDIHQVLRDIDSNA 106 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 G+I + ++ +L E + ++ +D D +G I EELK Sbjct: 107 SGQIHYTDFLAATIDKQTYL---------KKEVCLIPFKFFDIDGNGKISVEELKRIF-- 155 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 +++ + + D +L+ D N DG+++ E ++ + Sbjct: 156 ----GRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKK 196 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 55/142 (38%), Gaps = 18/142 (12%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 + D D+SG + ++E+ + LK + K+ +L+ DSN G++ Sbjct: 59 LRNIFIALDVDNSGTLSSQEILDGLKKIG--------YQKIPPDIHQVLRDIDSNASGQI 110 Query: 163 ELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKN 222 T+ ++ +L K + F+ +D DGNG I EL + + Sbjct: 111 HYTDFLAATIDKQTYLKKEVCLIP--------FKFFDIDGNGKISVEELKRIF--GRDDI 160 Query: 223 KQDLDINNITTYKKNIMALSDG 244 + L I + + + DG Sbjct: 161 ENPLIDKAIDSLLQEVDLNGDG 182 >4YZB-A nrPDB Length = 491 Score = 79.5 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 60/162 (37%), Gaps = 24/162 (14%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSP-----EMKTFVDQYGQRD 69 + +I+ D +G G L+ +EL EL + + + L E++ +D Sbjct: 340 ELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDK 399 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 +G I E V + L S + + + +D D SG I + EL Sbjct: 400 NGFIEYSEFVTV---------AMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFG- 449 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +E +L D NNDG+++ E ++L Sbjct: 450 ---------VSEVDSETWRRVLAEVDRNNDGEVDFEEFRQML 482 Score = 67.5 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 68/177 (38%), Gaps = 19/177 (10%) Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCE--EFMKTWRKYDTDHSGFIETEELKNFLKDL 130 + I + LL + + E E K +++ D + G ++ +EL +L Sbjct: 309 LNIRQFQGTQKLAAAALLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQELMEGYVEL 368 Query: 131 LEKANKTV---DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMC 187 ++ + V D + + + +L D + +G +E +E + ++ L Sbjct: 369 MKLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLL--------S 420 Query: 188 GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 + +AF ++D DG+G I +EL + ++D + +DG Sbjct: 421 RQRLERAFGMFDADGSGKISSSELATIF------GVSEVDSETWRRVLAEVDRNNDG 471 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 31/76 (40%), Gaps = 8/76 (10%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + +L++ + + FDADGSG + EL + S + + + Sbjct: 415 RKTLLSRQRLERAFGMFDADGSGKISSSELATIF--------GVSEVDSETWRRVLAEVD 466 Query: 67 QRDDGKIGIVELAHVL 82 + +DG++ E +L Sbjct: 467 RNNDGEVDFEEFRQML 482 >5ZOR-A nrPDB Length = 149 Score = 79.5 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 38/161 (23%), Positives = 62/161 (38%), Gaps = 21/161 (13%) Query: 11 ITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 +T Q E + FDADGSG ++ +E+ ++ L E++ V + Sbjct: 4 LTDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGD-----LPRDEVERTVRSMNTNAN 58 Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 G I E ++ + R Q S EE +K ++ +D D G I LK K L Sbjct: 59 GLIEYGEFERMVKS--------RMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLL 110 Query: 131 LEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E V M+ D + DG++ E ++ Sbjct: 111 GENPGDDVLQE--------MIAEADEDGDGEVSFEEFKSVM 143 Score = 58.7 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 14/122 (11%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 + E+ + + +D D SG I+ EE+ +K L + + ++ ++N Sbjct: 5 TDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFG-------DLPRDEVERTVRSMNTNA 57 Query: 159 DGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL 218 +G +E E R++ + K +E KAF+L+D D G I L + K L Sbjct: 58 NGLIEYGEFERMVKSRM-------AQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLL 110 Query: 219 CE 220 E Sbjct: 111 GE 112 Score = 34.4 bits (77), Expect = 0.046, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 29/62 (46%), Gaps = 3/62 (4%) Query: 183 GIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALS 242 + ++ +AF L+D DG+G ID E+ +K L + + + +++ + Sbjct: 1 MAALTDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPR---DEVERTVRSMNTNA 57 Query: 243 DG 244 +G Sbjct: 58 NG 59 >3IFK-A nrPDB Length = 90 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 14/96 (14%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 9 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 62 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWR 108 I E ++ + + S EE + +R Sbjct: 63 IDFPEFLTMMAR--------KMKDTDSEEEIREAFR 90 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 36/95 (37%), Gaps = 15/95 (15%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 62 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFE 196 ++ E ++ + +E +AF Sbjct: 63 IDFPEFLTMMARKM-------KDTDSEEEIREAFR 90 Score = 33.3 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 23/39 (58%) Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 Q + EF +AF L+D+DG+G I EL +++ L + Sbjct: 3 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 41 Score = 29.8 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 36/93 (38%), Gaps = 9/93 (9%) Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAF 195 + + ++AE+ + LFD + DG + E+ ++ + G E Sbjct: 2 DQLTEEQIAEFKEA-FSLFDKDGDGTITTKELGTVM--------RSLGQNPTEAELQDMI 52 Query: 196 ELYDQDGNGYIDENELDALLKDLCEKNKQDLDI 228 D DGNG ID E ++ + + +I Sbjct: 53 NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEI 85 Score = 27.1 bits (58), Expect = 7.6, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 24/76 (31%), Gaps = 9/76 (11%) Query: 52 LELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYD 111 E E K + + DG I EL V+ Q + E + D Sbjct: 6 EEQIAEFKEAFSLFDKDGDGTITTKELGTVM---------RSLGQNPTEAELQDMINEVD 56 Query: 112 TDHSGFIETEELKNFL 127 D +G I+ E + Sbjct: 57 ADGNGTIDFPEFLTMM 72 >3NCG-A nrPDB Length = 486 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 57/165 (34%), Gaps = 25/165 (15%) Query: 15 QFFEIWLHFDADGSGYLEGKEL----QNLIQELQQAR----KKAGLELSPEMKTFVDQYG 66 Q EI+ D + G L+ EL ++ + G + ++ + + Sbjct: 332 QLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLD 391 Query: 67 QRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 126 G I E L S E + ++ +D D SG I T+EL Sbjct: 392 MDGSGSIEYSEFIA---------SAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKL 442 Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 D + E + +++ D+N DG+++ E +L Sbjct: 443 F--------SQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEML 479 Score = 68.7 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 30/169 (17%), Positives = 69/169 (40%), Gaps = 18/169 (10%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL----KNFLKDLLEKANKT 137 L + + L ++ + +RK DT++ G ++ +EL F++ +N Sbjct: 312 LAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSL 371 Query: 138 VDDT--KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAF 195 + + + + D ++ L D + G +E +E + I + + +AF Sbjct: 372 IQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIA--------SAIDRTILLSRERMERAF 423 Query: 196 ELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +++D+DG+G I EL L + + + + + + + DG Sbjct: 424 KMFDKDGSGKISTKELFKLFS----QADSSIQMEELESIIEQVDNNKDG 468 Score = 48.3 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%) Query: 10 LITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 L++ + + FD DGSG + KEL L + + + E+++ ++Q Sbjct: 413 LLSRERMERAFKMFDKDGSGKISTKELFKLFSQADSSIQ------MEELESIIEQVDNNK 466 Query: 70 DGKIGIVELAHVL 82 DG++ E +L Sbjct: 467 DGEVDFNEFVEML 479 >2NA0-A nrPDB Length = 205 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 20/127 (15%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNF--LKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 S E + ++K+ T+ SG + E + F LK+L ++Y + M + FD Sbjct: 14 SSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSP---------WASQYVEQMFETFD 64 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 N DG ++ E L + ++ ++ F+LYD DGNG ID +EL ++ Sbjct: 65 FNKDGYIDFMEYEAALSLVLKGKVE--------QKLRWYFKLYDVDGNGCIDRDELLTII 116 Query: 216 KDLCEKN 222 + + N Sbjct: 117 RAIRAIN 123 Score = 56.0 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 26/148 (17%), Positives = 49/148 (33%), Gaps = 9/148 (6%) Query: 45 QARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFM 104 K S ++ + + DG I +E L + K ++ Sbjct: 43 FGLKNLSPWASQYVEQMFETFDFNKDGYIDFMEYEAALSL---------VLKGKVEQKLR 93 Query: 105 KTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 164 ++ YD D +G I+ +EL ++ + + E+TD + D N DG+L L Sbjct: 94 WYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSL 153 Query: 165 TEMARLLPVQENFLLKFQGIKMCGKEFN 192 E + + L + Sbjct: 154 EEFMEGVQKDQMLLDTLTRSLDLTRIVR 181 Score = 40.2 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQ-ARKKAGLELSPEM-KTFVDQYGQRDDGKIGIVE 77 + +D DG+G ++ EL +I+ ++ + E T + DG++ + E Sbjct: 96 FKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEE 155 Query: 78 LAHVLPTEENFL 89 + ++ L Sbjct: 156 FMEGVQKDQMLL 167 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 42/109 (38%), Gaps = 9/109 (8%) Query: 16 FFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGI 75 +++ FD + GY++ E + + + + + + L ++ Y +G I Sbjct: 56 VEQMFETFDFNKDGYIDFMEYEAALSLVLKGKVEQKLRWYFKL------YDVDGNGCIDR 109 Query: 76 VELAHVLPTEENFLLLFRCQQLKSCEEFMKT-WRKYDTDHSGFIETEEL 123 EL ++ + + EEF T + K D + G + EE Sbjct: 110 DELLTII--RAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEF 156 >5H7D-E nrPDB Length = 120 Score = 78.7 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 6/72 (8%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 55 IQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 108 Query: 73 IGIVELAHVLPT 84 I E ++ Sbjct: 109 IDFPEFLTMMAR 120 Score = 69.1 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 40/91 (43%), Gaps = 8/91 (8%) Query: 83 PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTK 142 ++ LL ++L + F + + +D D G I T+EL ++ L + + Sbjct: 38 DPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTE------ 91 Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 AE D M+ D++ +G ++ E ++ Sbjct: 92 -AELQD-MINEVDADGNGTIDFPEFLTMMAR 120 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Query: 172 PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNI 231 P Q LL + F +AF L+D+DG+G I EL +++ L + N + ++ + Sbjct: 39 PSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQ-NPTEAELQD- 96 Query: 232 TTYKKNIMALSDG 244 + A +G Sbjct: 97 --MINEVDADGNG 107 Score = 33.3 bits (74), Expect = 0.10, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 43/121 (35%), Gaps = 11/121 (9%) Query: 99 SCEEFMKTWRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYT--DLMLKLFD 155 + E +W + + +G + + L D + AN + KL + LFD Sbjct: 7 NKETQEASWEIFTLPNLNGRQVAAFISSLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFD 66 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 + DG + E+ ++ + G E D DGNG ID E ++ Sbjct: 67 KDGDGTITTKELGTVM--------RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 118 Query: 216 K 216 Sbjct: 119 A 119 Score = 32.9 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 33/106 (31%), Gaps = 17/106 (16%) Query: 30 YLEGKELQNLIQELQQARKKAGLELS--------PEMKTFVDQYGQRDDGKIGIVELAHV 81 L G+++ I L ++ L+ K + + DG I EL V Sbjct: 22 NLNGRQVAAFISSLLDDPSQSANLLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTV 81 Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 + Q + E + D D +G I+ E + Sbjct: 82 M---------RSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 118 >2BL0-B nrPDB Length = 145 Score = 77.6 bits (189), Expect = 5e-15, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 57/160 (35%), Gaps = 24/160 (15%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 +A Q E + FD D G + +EL + ++ L + A L G Sbjct: 3 SADQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAEL--------------NTIKG 48 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 ++ E L T + + +E + +R D + +G I+ EL+ L +L Sbjct: 49 QLNAKEFD--LATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLG 106 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + + + ++K + DG + +L Sbjct: 107 DALT--------SSEVEELMKEVSVSGDGAINYESFVDML 138 Score = 65.6 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 34/154 (22%), Positives = 58/154 (37%), Gaps = 21/154 (13%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 S ++ + ++ +D D+ G + EEL + L+ L + +T Sbjct: 1 TASADQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIK------------- 47 Query: 157 NNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 G+L E L + + + KE AF D++GNG I E EL LL Sbjct: 48 ---GQLNAKEF-DLATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLL 103 Query: 217 DLCEKNKQDLDINNITTYKKNIMALSDGGKLYRT 250 +L + L + + K + DG Y + Sbjct: 104 NLGD----ALTSSEVEELMKEVSVSGDGAINYES 133 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 32/80 (40%), Gaps = 6/80 (7%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 +++ + + + + D +G+G ++ EL+ L+ L A S E++ + Sbjct: 65 RKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALT------SSEVEELM 118 Query: 63 DQYGQRDDGKIGIVELAHVL 82 + DG I +L Sbjct: 119 KEVSVSGDGAINYESFVDML 138 >4RGJ-A nrPDB Length = 520 Score = 77.6 bits (189), Expect = 6e-15, Method: Composition-based stats. Identities = 40/175 (22%), Positives = 65/175 (37%), Gaps = 27/175 (15%) Query: 5 HLQSSLITASQFFE---IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLEL-----SP 56 ++ S L T + E I+ D +G G L+ EL +EL + + + +L Sbjct: 359 YMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEY 418 Query: 57 EMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116 E+ ++ +G I E V + L S E K ++ +D D SG Sbjct: 419 EVDQILNSIDLDQNGYIEYSEFLTV---------SIDRKLLLSTERLEKAFKLFDKDGSG 469 Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 I EL +E +LK D NNDG+++ E +L Sbjct: 470 KISANELAQLFG----------LSDVSSECWKTVLKEVDQNNDGEIDFKEFRDML 514 Score = 71.8 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 37/167 (22%), Positives = 67/167 (40%), Gaps = 19/167 (11%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL----KNFLKDLLEKANKT 137 L + + + +E K ++K D + G ++ EL K LK E + Sbjct: 352 LAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSD- 410 Query: 138 VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFEL 197 +D+ + D +L D + +G +E +E + + + + + KAF+L Sbjct: 411 LDNAAIEYEVDQILNSIDLDQNGYIEYSEFLTV--------SIDRKLLLSTERLEKAFKL 462 Query: 198 YDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +D+DG+G I NEL L D+ T K + +DG Sbjct: 463 FDKDGSGKISANELAQLF------GLSDVSSECWKTVLKEVDQNNDG 503 >5COC-A nrPDB Length = 130 Score = 77.2 bits (188), Expect = 7e-15, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 6/74 (8%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 62 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 115 Query: 73 IGIVELAHVLPTEE 86 I E ++ + Sbjct: 116 IDFPEFLTMMARKM 129 Score = 66.4 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 31/75 (41%), Gaps = 8/75 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 115 Query: 162 LELTEMARLLPVQEN 176 ++ E ++ + Sbjct: 116 IDFPEFLTMMARKMK 130 Score = 36.7 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 23/36 (63%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + C EF +AF L+D+DG+G I EL +++ L + Sbjct: 59 EECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 94 Score = 31.3 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 33/96 (34%), Gaps = 12/96 (12%) Query: 129 DLLEKANKTVDDTKLAEYTDLMLKL----FDSNNDGKLELTEMARLLPVQENFLLKFQGI 184 +LL +A D AE K FD + DG + E+ ++ + G Sbjct: 43 NLLAEAKCLNDAQAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVM--------RSLGQ 94 Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 E D DGNG ID E ++ + Sbjct: 95 NPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMK 130 Score = 31.3 bits (69), Expect = 0.38, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 26/82 (31%), Gaps = 9/82 (10%) Query: 46 ARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMK 105 + A E E K + + DG I EL V+ Q + E Sbjct: 53 DAQAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVM---------RSLGQNPTEAELQD 103 Query: 106 TWRKYDTDHSGFIETEELKNFL 127 + D D +G I+ E + Sbjct: 104 MINEVDADGNGTIDFPEFLTMM 125 >3L19-A nrPDB Length = 214 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 64/162 (39%), Gaps = 23/162 (14%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSP---EMKTFVDQYGQRDDG 71 + +I+ H D +G G L+ +EL + +L + A +L E+ + +G Sbjct: 64 ELTDIFRHIDKNGDGQLDRQELIDGYSKL-SGEEVAVFDLPQIESEVDAILGAADFDRNG 122 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I E V + L S ++ ++K+D D +G I +EL + Sbjct: 123 YIDYSEFVTV---------AMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVFG--- 170 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 D ++ M+ DSNNDG ++ E +++ Sbjct: 171 -------LDHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 205 Score = 66.0 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 62/163 (38%), Gaps = 14/163 (8%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 141 L + + + +E +R D + G ++ +EL + L + D Sbjct: 44 LAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLP 103 Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 ++ D +L D + +G ++ +E + +++ L + AF+ +DQD Sbjct: 104 QIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLL--------SKDKLESAFQKFDQD 155 Query: 202 GNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 GNG I +EL ++ L+ I + +DG Sbjct: 156 GNGKISVDELASVF------GLDHLESKTWKEMISGIDSNNDG 192 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 28/78 (35%), Gaps = 8/78 (10%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + SL++ + + FD DG+G + EL ++ S K + Sbjct: 136 RKSLLSKDKLESAFQKFDQDGNGKISVDELASVF--------GLDHLESKTWKEMISGID 187 Query: 67 QRDDGKIGIVELAHVLPT 84 +DG + E ++ Sbjct: 188 SNNDGDVDFEEFCKMIQK 205 >3KHE-A nrPDB Length = 191 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 36/164 (21%), Positives = 66/164 (40%), Gaps = 24/164 (14%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQ--ARKKAGL---ELSPEMKTFVDQYGQRD 69 + +I+ D +G G L+ KEL ++L Q + L ++ E+ + Sbjct: 41 ELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVDFDR 100 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 +G I E V ++ L S E + ++++D+D SG I EEL Sbjct: 101 NGYIEYSEFVTVCMDKQLLL---------SRERLLAAFQQFDSDGSGKITNEELGRLF-- 149 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 + D+T +L+ D NNDG+++ E ++ Sbjct: 150 ---GVTEVDDETW-----HQVLQECDKNNDGEVDFEEFVEMMQK 185 Score = 59.8 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 66/166 (39%), Gaps = 17/166 (10%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 141 L + + L+ +E + +R+ D + G ++ +EL + L++ TV D Sbjct: 21 LAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDL 80 Query: 142 KLAE---YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELY 198 ++ D +L+ D + +G +E +E + ++ + + + AF+ + Sbjct: 81 DSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQ--------LLLSRERLLAAFQQF 132 Query: 199 DQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 D DG+G I EL L ++D + +DG Sbjct: 133 DSDGSGKITNEELGRLF------GVTEVDDETWHQVLQECDKNNDG 172 >3Q5I-A nrPDB Length = 504 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 35/159 (22%), Positives = 58/159 (36%), Gaps = 21/159 (13%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGL--ELSPEMKTFVDQYGQRDDGK 72 + +I+ D +G G L+ KEL L+ + + G + E+ + + +G Sbjct: 356 ELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDFDKNGY 415 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E V Q L S E + + +DTD SG I EEL N Sbjct: 416 IEYSEFISV---------CMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLF----- 461 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + T + +L D N D ++ E ++ Sbjct: 462 GLTSISEKTW-----NDVLGEADQNKDNMIDFDEFVSMM 495 Score = 72.2 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 63/152 (41%), Gaps = 10/152 (6%) Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 E + L + + L+ +E ++K D + G ++ +EL L N+ Sbjct: 331 EGSQKLAQAAILFIGSKLTTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNE 390 Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFE 196 + + E D +LK D + +G +E +E + ++ I + +AF Sbjct: 391 LGELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQ--------ILFSEERLRRAFN 442 Query: 197 LYDQDGNGYIDENELDAL--LKDLCEKNKQDL 226 L+D D +G I + EL L L + EK D+ Sbjct: 443 LFDTDKSGKITKEELANLFGLTSISEKTWNDV 474 >1GGW-A nrPDB Length = 140 Score = 76.0 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 60/160 (37%), Gaps = 25/160 (15%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 S + + + FD G+G + + +L++ Q A + + Sbjct: 3 DDSPYKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAE----------ITEIESTLPA 52 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 ++ + + VL F + EEF+K ++ +D D +G I EL+ L L Sbjct: 53 EVDMEQFLQVLNRPNGFDM------PGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSLG 106 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 EK + E D +LK DG + + +++ Sbjct: 107 EKLS--------NEEMDELLKGVPV-KDGMVNYHDFVQMI 137 Score = 58.7 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 47/123 (38%), Gaps = 17/123 (13%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 + + + +D +G I + + L+ + + +S ++ Sbjct: 7 YKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAE------------ITEIESTLPAEV 54 Query: 163 ELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKN 222 ++ + ++L F + +EF K F+++D+D G I EL +L L EK Sbjct: 55 DMEQFLQVLNRPNGFDMPGDP-----EEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKL 109 Query: 223 KQD 225 + Sbjct: 110 SNE 112 >2AAO-A nrPDB Length = 166 Score = 75.6 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 25/162 (15%), Positives = 61/162 (37%), Gaps = 25/162 (15%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + E++ DAD SG + +EL+ ++ + K++ E+ + + G Sbjct: 25 EIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKES------EILDLMQAADVDNSG 78 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I E +++ + + +D D SG+I +EL+ ++ Sbjct: 79 TIDYKEFIAA---------TLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFG 129 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 + + +++ D +NDG+++ E ++ Sbjct: 130 VEDV----------RIEELMRDVDQDNDGRIDYNEFVAMMQK 161 Score = 59.8 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 25/159 (15%) Query: 89 LLLFRCQQLKSCEE---FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE 145 + L + S EE + + D D SG I EELK LK + + +E Sbjct: 12 MALRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKE-------SE 64 Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 DLM + D +N G ++ E AF +D+DG+GY Sbjct: 65 ILDLM-QAADVDNSGTIDYKEFIAA--------TLHLNKIEREDHLFAAFTYFDKDGSGY 115 Query: 206 IDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 I +EL ++ ++ I +++ +DG Sbjct: 116 ITPDELQQACEEFG------VEDVRIEELMRDVDQDNDG 148 >2BL0-C nrPDB Length = 142 Score = 75.6 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 62/159 (38%), Gaps = 23/159 (14%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 S+F E + FD++ +G++ + LQ ++++ + ++ +GK Sbjct: 5 VSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVE------PAAFNEMFNEADATGNGK 58 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I E ++ R +Q S + + +R +D + +G+I L++ L +L Sbjct: 59 IQFPEFLSMMGR--------RMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLG- 109 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + + AE+ + + G++ + Sbjct: 110 ---DRLKPHEFAEFLG--ITETEK---GQIRYDNFINTM 140 Score = 72.6 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 26/127 (20%), Positives = 49/127 (38%), Gaps = 15/127 (11%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 EF + + +D++ +GFI E L+ LK + + M D+ Sbjct: 3 DQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNE--------MFNEADAT 54 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 +GK++ E ++ + +AF +D +G GYI + L L + Sbjct: 55 GNGKIQFPEFLSMMGRRM-------KQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLN 107 Query: 218 LCEKNKQ 224 L ++ K Sbjct: 108 LGDRLKP 114 >1W7I-B nrPDB Length = 151 Score = 74.9 bits (182), Expect = 3e-14, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 66/165 (40%), Gaps = 21/165 (12%) Query: 6 LQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAG-LELSPEMKTFVDQ 64 ++ + +F E + FD G G + + ++++ L Q A L++ K+ Sbjct: 2 IEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKS---- 57 Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + ++ +L + + + E++++ +R +D + +G + EL+ Sbjct: 58 -DELKSRRVDFETFLPMLQAVA------KNRGQGTYEDYLEGFRVFDKEGNGKVMGAELR 110 Query: 125 NFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + L L EK + +T LA + +++G + + Sbjct: 111 HVLTTLGEKMTEEEVETVLAGH---------EDSNGCINYEAFLK 146 Score = 70.6 bits (171), Expect = 6e-13, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 46/129 (35%), Gaps = 11/129 (8%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 EEF + + +D G I + + ++ L + L D Sbjct: 6 KDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKS------DE 59 Query: 157 NNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 +++ +L + +++ + F ++D++GNG + EL +L Sbjct: 60 LKSRRVDFETFLPMLQAVAKNRGQGTY-----EDYLEGFRVFDKEGNGKVMGAELRHVLT 114 Query: 217 DLCEKNKQD 225 L EK ++ Sbjct: 115 TLGEKMTEE 123 >4Q57-A nrPDB Length = 65 Score = 74.1 bits (180), Expect = 6e-14, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 33/71 (46%), Gaps = 6/71 (8%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD DG G + KEL +++ L Q +A E++ +++ +G Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA------ELQDMINEVDADGNGT 54 Query: 73 IGIVELAHVLP 83 I E ++ Sbjct: 55 IDFPEFLTMMA 65 Score = 63.7 bits (153), Expect = 7e-11, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 54 Query: 162 LELTEMARLLP 172 ++ E ++ Sbjct: 55 IDFPEFLTMMA 65 Score = 35.6 bits (80), Expect = 0.022, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 21/32 (65%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 EF +AF L+D+DG+G I EL +++ L + Sbjct: 2 AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQ 33 Score = 29.8 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 24/71 (33%), Gaps = 8/71 (11%) Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 LFD + DG + E+ ++ + G E D DGNG Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVM--------RSLGQNPTEAELQDMINEVDADGNGT 54 Query: 206 IDENELDALLK 216 ID E ++ Sbjct: 55 IDFPEFLTMMA 65 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 23/71 (32%), Gaps = 9/71 (12%) Query: 57 EMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116 E K + + DG I EL V+ Q + E + D D +G Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVM---------RSLGQNPTEAELQDMINEVDADGNG 53 Query: 117 FIETEELKNFL 127 I+ E + Sbjct: 54 TIDFPEFLTMM 64 >2I94-A nrPDB Length = 202 Score = 73.3 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 28/128 (21%), Positives = 52/128 (40%), Gaps = 16/128 (12%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + EE ++ + + SG I +E + +A+ Y + + FD+N Sbjct: 24 TEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEADPKA-------YAQHVFRSFDAN 76 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 +DG L+ E L + ++ AF LYD DGNG I +NE+ ++ Sbjct: 77 SDGTLDFKEYVIALHMTSAGK--------TNQKLEWAFSLYDVDGNGTISKNEVLEIVTA 128 Query: 218 LCEKNKQD 225 + + + Sbjct: 129 IFKMISPE 136 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 21/148 (14%), Positives = 44/148 (29%), Gaps = 20/148 (13%) Query: 28 SGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEEN 87 SG + +E Q + + + + DG + E Sbjct: 41 SGRITRQEFQTIYSKFFPEADPKAYA-----QHVFRSFDANSDGTLDFKEYV-------- 87 Query: 88 FLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT------VDDT 141 + L K+ ++ + YD D +G I E+ + + + + D+ Sbjct: 88 -IALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTAIFKMISPEDTKHLPEDEN 146 Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + + + F +D KL E Sbjct: 147 TPEKRAEKIWGFFGKKDDDKLTEKEFIE 174 Score = 31.7 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 35/110 (31%), Gaps = 11/110 (10%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 ++ FDA+ G L+ KE + + LE + + Y +G I E+ Sbjct: 69 VFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSL------YDVDGNGTISKNEV 122 Query: 79 AHVLPTEENFLLLFRCQ-----QLKSCEEFMKTWRKYDTDHSGFIETEEL 123 ++ + + + + K W + + +E Sbjct: 123 LEIVTAIFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEF 172 Score = 27.5 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 40/101 (39%), Gaps = 8/101 (7%) Query: 5 HLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQ 64 H+ S+ T + + +D DG+G + E+ ++ + + + PE + ++ Sbjct: 91 HMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTAIFKMISPEDTKHLPEDENTPEK 150 Query: 65 --------YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQL 97 +G++DD K+ E + L L + + Sbjct: 151 RAEKIWGFFGKKDDDKLTEKEFIEGTLANKEILRLIQFEPQ 191 >3JAX-C nrPDB Length = 151 Score = 73.3 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 68/159 (42%), Gaps = 21/159 (13%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVD-QYGQRDDGK 72 ++F E + FD G G + + ++++ L Q A + MK + + + + Sbjct: 10 AEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEV-----MKVLGNPKSDEMNLKT 64 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + ++ T + + + E++++ R +D + +G + E+++ L L E Sbjct: 65 LKFEQFLPMMQT------IAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGE 118 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 K + + +A + +++G + E+ R++ Sbjct: 119 KMTEEEVEQLVAGH---------EDSNGCINYEELVRMV 148 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 48/124 (38%), Gaps = 11/124 (8%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + ++ +D G I + + ++ L + L D N Sbjct: 11 EFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKS------DEMNLKT 64 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 L+ + ++ + + C +++ + ++D++GNG + E+ +L L EK Sbjct: 65 LKFEQFLPMMQ-----TIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEK 119 Query: 222 NKQD 225 ++ Sbjct: 120 MTEE 123 Score = 29.4 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 22/36 (61%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + EF +AF+L+D+ G+G I ++ +++ L + Sbjct: 6 EEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQ 41 >2RO8-A nrPDB Length = 79 Score = 72.6 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 6/80 (7%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 Q + S+F E + FD DG G + KEL +++ L Q +A E++ +++ Sbjct: 3 QLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEA------ELQDMINEVD 56 Query: 67 QRDDGKIGIVELAHVLPTEE 86 +G I E +++ + Sbjct: 57 ADGNGTIDFPEFLNLMARKM 76 Score = 60.2 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 31/75 (41%), Gaps = 8/75 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D G I T+EL ++ L + + M+ D++ +G Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEA--------ELQDMINEVDADGNGT 62 Query: 162 LELTEMARLLPVQEN 176 ++ E L+ + Sbjct: 63 IDFPEFLNLMARKMK 77 Score = 35.2 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 21/31 (67%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCE 220 EF +AF L+D+DG+G I EL +++ L + Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQ 41 Score = 31.0 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 33/87 (37%), Gaps = 9/87 (10%) Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAF 195 + D +++E+ + LFD + DG + E+ ++ + G E Sbjct: 2 DQLTDEQISEFKEA-FSLFDKDGDGCITTKELGTVM--------RSLGQNPTEAELQDMI 52 Query: 196 ELYDQDGNGYIDENELDALLKDLCEKN 222 D DGNG ID E L+ + Sbjct: 53 NEVDADGNGTIDFPEFLNLMARKMKDT 79 Score = 28.3 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 24/72 (33%), Gaps = 9/72 (12%) Query: 56 PEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHS 115 E K + + DG I EL V+ Q + E + D D + Sbjct: 10 SEFKEAFSLFDKDGDGCITTKELGTVM---------RSLGQNPTEAELQDMINEVDADGN 60 Query: 116 GFIETEELKNFL 127 G I+ E N + Sbjct: 61 GTIDFPEFLNLM 72 >2KN2-A nrPDB Length = 92 Score = 72.2 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 8/76 (10%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + EE + ++ +D D +G+I EL++ + +L EK E + M+K D Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEAD 55 Query: 156 SNNDGKLELTEMARLL 171 + DG++ E +++ Sbjct: 56 LDGDGQVNYEEFVKMM 71 Score = 50.2 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 183 GIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALS 242 +E +AF+++D+D NGYI +EL ++ +L EK + + K Sbjct: 3 MDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDE----EVEQMIKEADLDG 58 Query: 243 DG 244 DG Sbjct: 59 DG 60 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 30/68 (44%), Gaps = 6/68 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + E + FD D +GY+ EL++++ L + E++ + + DG++ Sbjct: 10 ELKEAFKVFDKDQNGYISASELRHVMINLGEKLTD------EEVEQMIKEADLDGDGQVN 63 Query: 75 IVELAHVL 82 E ++ Sbjct: 64 YEEFVKMM 71 Score = 31.0 bits (68), Expect = 0.50, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 34/80 (42%), Gaps = 8/80 (10%) Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD 199 DT E K+FD + +G + +E+ ++ G K+ +E + + D Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVM--------INLGEKLTDEEVEQMIKEAD 55 Query: 200 QDGNGYIDENELDALLKDLC 219 DG+G ++ E ++ + Sbjct: 56 LDGDGQVNYEEFVKMMMTVR 75 >1FW4-A nrPDB Length = 71 Score = 72.2 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 8/79 (10%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 S EE + +R +D D +G+I EL++ + +L EK E D M++ D Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIREAD 52 Query: 156 SNNDGKLELTEMARLLPVQ 174 + DG++ E +++ + Sbjct: 53 IDGDGQVNYEEFVQMMTAK 71 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 184 IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 +E +AF ++D+DGNGYI EL ++ +L EK + + + D Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDE----EVDEMIREADIDGD 56 Query: 244 G 244 G Sbjct: 57 G 57 Score = 47.9 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 32/74 (43%), Gaps = 6/74 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + E + FD DG+GY+ EL++++ L + E+ + + DG Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD------EEVDEMIREADIDGDG 57 Query: 72 KIGIVELAHVLPTE 85 ++ E ++ + Sbjct: 58 QVNYEEFVQMMTAK 71 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 32/78 (41%), Gaps = 8/78 (10%) Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD 199 DT E ++FD + +G + E+ ++ G K+ +E ++ D Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMT--------NLGEKLTDEEVDEMIREAD 52 Query: 200 QDGNGYIDENELDALLKD 217 DG+G ++ E ++ Sbjct: 53 IDGDGQVNYEEFVQMMTA 70 >2HF5-A nrPDB Length = 68 Score = 72.2 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 34/75 (45%), Gaps = 8/75 (10%) Query: 57 EMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116 E++ +++ +G I E ++ + + S EE + +R +D D +G Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMAR--------KMKDTDSEEEIREAFRVFDKDGNG 53 Query: 117 FIETEELKNFLKDLL 131 +I EL++ + +L Sbjct: 54 YISAAELRHVMTNLG 68 Score = 70.6 bits (171), Expect = 7e-13, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 M+ D++ +G ++ E ++ + +E +AF ++D+DGNGY Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKM-------KDTDSEEEIREAFRVFDKDGNGY 54 Query: 206 IDENELDALLKDLC 219 I EL ++ +L Sbjct: 55 ISAAELRHVMTNLG 68 Score = 34.8 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 18/30 (60%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQ 44 + E + FD DG+GY+ EL++++ L Sbjct: 39 EIREAFRVFDKDGNGYISAAELRHVMTNLG 68 Score = 31.7 bits (70), Expect = 0.28, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 26/71 (36%), Gaps = 7/71 (9%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 E + D D +G I+ E + + DT E ++FD + +G Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMAR-------KMKDTDSEEEIREAFRVFDKDGNGY 54 Query: 162 LELTEMARLLP 172 + E+ ++ Sbjct: 55 ISAAELRHVMT 65 Score = 29.0 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 5/70 (7%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++ ++ DADG+G ++ E ++ ARK + E++ + + +G I Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMM-----ARKMKDTDSEEEIREAFRVFDKDGNGYI 55 Query: 74 GIVELAHVLP 83 EL HV+ Sbjct: 56 SAAELRHVMT 65 >2KZ2-A nrPDB Length = 94 Score = 71.4 bits (173), Expect = 4e-13, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 8/81 (9%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 + S EE + +R D D +G+I EL++ + +L EK E D M++ Sbjct: 22 MKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTD--------EEVDEMIRE 73 Query: 154 FDSNNDGKLELTEMARLLPVQ 174 D + DG++ E +++ + Sbjct: 74 ADIDGDGQVNYEEFVQMMTAK 94 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 4/62 (6%) Query: 183 GIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALS 242 +E +AF + D+DGNGYI EL ++ +L EK + + + Sbjct: 23 KDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDE----EVDEMIREADIDG 78 Query: 243 DG 244 DG Sbjct: 79 DG 80 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 31/74 (41%), Gaps = 6/74 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + E + D DG+GY+ EL++++ L + E+ + + DG Sbjct: 27 SEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTD------EEVDEMIREADIDGDG 80 Query: 72 KIGIVELAHVLPTE 85 ++ E ++ + Sbjct: 81 QVNYEEFVQMMTAK 94 Score = 29.0 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 32/81 (39%), Gaps = 8/81 (9%) Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFE 196 + DT E ++ D + +G + E+ ++ G K+ +E ++ Sbjct: 21 LMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMT--------NLGEKLTDEEVDEMIR 72 Query: 197 LYDQDGNGYIDENELDALLKD 217 D DG+G ++ E ++ Sbjct: 73 EADIDGDGQVNYEEFVQMMTA 93 >2I08-A nrPDB Length = 78 Score = 71.0 bits (172), Expect = 5e-13, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + +D DG G + KEL +++ L +A E++ +++ +G Sbjct: 9 IAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEA------ELQDMINEVDADGNGT 62 Query: 73 IGIVELAHVLPT 84 I E ++ Sbjct: 63 IDFPEFLTMMAR 74 Score = 61.8 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 8/76 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + YD D G I T+EL ++ L + M+ D++ +G Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEA--------ELQDMINEVDADGNGT 62 Query: 162 LELTEMARLLPVQENF 177 ++ E ++ + Sbjct: 63 IDFPEFLTMMARIMKY 78 Score = 35.2 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 22/38 (57%) Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 Q + EF +AF LYD+DG+G I EL +++ L Sbjct: 3 QLTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLG 40 Score = 32.9 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 35/85 (41%), Gaps = 9/85 (10%) Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAF 195 + + ++AE+ + L+D + DG + E+ ++ + G+ E Sbjct: 2 DQLTEEQIAEFKEA-FSLYDKDGDGTITTKELGTVM--------RSLGLNPTEAELQDMI 52 Query: 196 ELYDQDGNGYIDENELDALLKDLCE 220 D DGNG ID E ++ + + Sbjct: 53 NEVDADGNGTIDFPEFLTMMARIMK 77 Score = 29.4 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 26/82 (31%), Gaps = 9/82 (10%) Query: 52 LELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYD 111 E E K Y + DG I EL V+ + E + D Sbjct: 6 EEQIAEFKEAFSLYDKDGDGTITTKELGTVM---------RSLGLNPTEAELQDMINEVD 56 Query: 112 TDHSGFIETEELKNFLKDLLEK 133 D +G I+ E + +++ Sbjct: 57 ADGNGTIDFPEFLTMMARIMKY 78 >4ORC-B nrPDB Length = 170 Score = 70.6 bits (171), Expect = 7e-13, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 58/152 (38%), Gaps = 21/152 (13%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELA 79 + D D SG L +E +L L+ +P ++ +D + +G++ E Sbjct: 27 FKKLDLDNSGSLSVEEFMSL----------PELQQNPLVQRVIDIFDTDGNGEVDFKEFI 76 Query: 80 HVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD 139 + + ++ +R YD D G+I EL LK + + Sbjct: 77 EGVSQFSV--------KGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMM---VGNNLK 125 Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 DT+L + D + D + DG++ E ++ Sbjct: 126 DTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 Score = 65.6 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 59/150 (39%), Gaps = 20/150 (13%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + K ++K D D+SG + EE ++ + + ++ +FD Sbjct: 16 DADEIKRLGKRFKKLDLDNSGSLSVEEF------------MSLPELQQNPLVQRVIDIFD 63 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 ++ +G+++ E + +F ++ AF +YD D +GYI EL +L Sbjct: 64 TDGNGEVDFKEFIE-------GVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVL 116 Query: 216 KDLCEKNKQDLDINNI-TTYKKNIMALSDG 244 K + N +D + I N DG Sbjct: 117 KMMVGNNLKDTQLQQIVDKTIINADKDGDG 146 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 28/165 (16%), Positives = 63/165 (38%), Gaps = 23/165 (13%) Query: 64 QYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL 123 + + G + + E + ++N L + +DTD +G ++ +E Sbjct: 29 KLDLDNSGSLSVEEFMSLPELQQNPL-------------VQRVIDIFDTDGNGEVDFKE- 74 Query: 124 KNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQG 183 +E ++ + +++D + DG + E+ ++L + LK Sbjct: 75 ------FIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 128 Query: 184 IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDI 228 + + +K D+DG+G I E A++ L K +D+ Sbjct: 129 L---QQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV 170 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 29/81 (35%), Gaps = 1/81 (1%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + + +D D GY+ EL +++ + K +L + + + DG+I Sbjct: 90 QKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLK-DTQLQQIVDKTIINADKDGDGRI 148 Query: 74 GIVELAHVLPTEENFLLLFRC 94 E V+ + + Sbjct: 149 SFEEFCAVVGGLDIHKKMVVD 169 >4WPX-A nrPDB Length = 177 Score = 70.2 bits (170), Expect = 8e-13, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 59/175 (33%), Gaps = 16/175 (9%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 E + + S ++ E + FD++ G L +E + +++ L K V Sbjct: 15 EDYNKLSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPK-----QQTYDMLV 69 Query: 63 DQYGQRDDGKIGI---VELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIE 119 + + L +Q +E + +R +D D G I Sbjct: 70 RHGQRPANWPHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMIT 129 Query: 120 TEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 ++L+ + + M++ FDSN G ++ E RL+ + Sbjct: 130 EDDLRKVCQQVGNNI--------PDADIQAMIEEFDSNGKGGVDEDEFLRLMMSK 176 Score = 54.8 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 66/183 (36%), Gaps = 11/183 (6%) Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKA 134 ++ + +P E++ L Q+ + + + +D++ G + EE + L+ L Sbjct: 4 TRQIQYTIPPREDYNKLSDEQKTR----ISEAFELFDSNKDGLLSYEEFRFVLRALGFDL 59 Query: 135 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKA 194 K L + + + + + L Q + E +A Sbjct: 60 PKQQTYDMLVRHGQRPAN-WPHDQECPPVYRQFNLATAQALAGTLIRQ--RDPRDELRRA 116 Query: 195 FELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDLAL 254 F L+D DG G I E++L + + + N D D I + + GG L L Sbjct: 117 FRLFDVDGKGMITEDDLRKVCQQVGN-NIPDAD---IQAMIEEFDSNGKGGVDEDEFLRL 172 Query: 255 ILC 257 ++ Sbjct: 173 MMS 175 >5XND-A nrPDB Length = 114 Score = 70.2 bits (170), Expect = 8e-13, Method: Composition-based stats. Identities = 37/118 (31%), Positives = 49/118 (41%), Gaps = 21/118 (17%) Query: 71 GKIGIVELAHVLPTEENFLLLFRCQ----------------QLKSCEEFMKTWRKYDTDH 114 G +G + A VL E L C+ KS +E K + D D Sbjct: 1 GPLGSMAFASVLKDAEVTAALDGCKAAGSFDHKKFFKACGLSGKSTDEVKKAFAIIDQDK 60 Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 SGFIE EELK FL++ A D T LK DS+ DGK+ + E A ++ Sbjct: 61 SGFIEEEELKLFLQNFKAGARALSDAE-----TKAFLKAGDSDGDGKIGIDEFAAMIK 113 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + + + D D SG++E +EL+ +Q + + E K F+ DGKIG Sbjct: 48 EVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALS---DAETKAFLKAGDSDGDGKIG 104 Query: 75 IVELAHVLP 83 I E A ++ Sbjct: 105 IDEFAAMIK 113 Score = 31.3 bits (69), Expect = 0.43, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 26/58 (44%), Gaps = 1/58 (1%) Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 E KAF + DQD +G+I+E EL L++ + D + K + DG Sbjct: 45 STDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDA-ETKAFLKAGDSDGDG 101 >2M5E-A nrPDB Length = 73 Score = 70.2 bits (170), Expect = 9e-13, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 8/81 (9%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 ++ S EE ++ ++ +D D +G I EL++ + +L EK + D M++ Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTD--------DEVDEMIRE 52 Query: 154 FDSNNDGKLELTEMARLLPVQ 174 D + DG + E R++ + Sbjct: 53 ADIDGDGHINYEEFVRMMVSK 73 Score = 47.9 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 4/62 (6%) Query: 183 GIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALS 242 + +E +AF+++D+DGNG I EL ++ +L EK L + + + Sbjct: 2 KEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEK----LTDDEVDEMIREADIDG 57 Query: 243 DG 244 DG Sbjct: 58 DG 59 Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + E + FD DG+G + EL++++ L + E+ + + DG I Sbjct: 9 ELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDD------EVDEMIREADIDGDGHIN 62 Query: 75 IVELAHVLPTE 85 E ++ ++ Sbjct: 63 YEEFVRMMVSK 73 Score = 28.6 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 32/80 (40%), Gaps = 8/80 (10%) Query: 138 VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFEL 197 + + E K+FD + +G + E+ ++ G K+ E ++ Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMT--------NLGEKLTDDEVDEMIRE 52 Query: 198 YDQDGNGYIDENELDALLKD 217 D DG+G+I+ E ++ Sbjct: 53 ADIDGDGHINYEEFVRMMVS 72 Score = 26.7 bits (57), Expect = 9.5, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 27/77 (35%), Gaps = 9/77 (11%) Query: 51 GLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKY 110 + E+ + + +G I EL HV+ L + +E + R+ Sbjct: 3 EQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKL---------TDDEVDEMIREA 53 Query: 111 DTDHSGFIETEELKNFL 127 D D G I EE + Sbjct: 54 DIDGDGHINYEEFVRMM 70 >2JNF-A nrPDB Length = 158 Score = 69.9 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 30/170 (17%), Positives = 70/170 (41%), Gaps = 21/170 (12%) Query: 4 SHLQSSLITASQFFEIWLHFDA-DGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 S L S+ + + + F+ +GSG + ++ +++ L + K+ + + Sbjct: 5 SKLSSNQVKLLE--TAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIR------QLI 56 Query: 63 DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEE 122 D++ +G I + L + +E + +R YD + +G+I T+ Sbjct: 57 DEFDPFGNGDIDFDSFKIIGAR----FLGEEVNPEQMQQELREAFRLYDKEGNGYISTDV 112 Query: 123 LKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 ++ L +L D+T +E D M+ D++ G ++ E ++ Sbjct: 113 MREILAEL--------DETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMT 154 Score = 59.5 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 16/143 (11%) Query: 103 FMKTWRKYDT-DHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 +R ++T + SG + T+++ L+ L + K+ ++ FD +G Sbjct: 15 LETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKST--------IRQLIDEFDPFGNGD 66 Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ + FL + + +E +AF LYD++GNGYI + + +L +L E Sbjct: 67 IDFDSFKIIGA---RFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAELDE- 122 Query: 222 NKQDLDINNITTYKKNIMALSDG 244 L ++ I A G Sbjct: 123 ---TLSSEDLDAMIDEIDADGSG 142 Score = 37.9 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 22/148 (14%), Positives = 52/148 (35%), Gaps = 11/148 (7%) Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 E + + T++ ++L ++ + ++D +G I+ + K Sbjct: 22 FETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFDPFGNGDIDFDSFKIIGARF-- 79 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 + V+ ++ + +L+D +G + M +L + L M + Sbjct: 80 -LGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDE--- 135 Query: 193 KAFELYDQDGNGYIDENELDALLKDLCE 220 D DG+G +D E ++ E Sbjct: 136 -----IDADGSGTVDFEEFMGVMTGGDE 158 Score = 33.3 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 43/121 (35%), Gaps = 10/121 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T S ++ FD G+G ++ + + + ++ E++ Y + +G Sbjct: 48 TKSTIRQLIDEFDPFGNGDIDFDSFKIIGARFL-GEEVNPEQMQQELREAFRLYDKEGNG 106 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I + +L + L S E+ + D D SG ++ EE + Sbjct: 107 YISTDVMREILAELDETL---------SSEDLDAMIDEIDADGSGTVDFEEFMGVMTGGD 157 Query: 132 E 132 E Sbjct: 158 E 158 >5MWC-D nrPDB Length = 311 Score = 69.5 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 40/103 (38%), Gaps = 12/103 (11%) Query: 69 DDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLK 128 + ++ P N L S EE + +R +D D GFI+ EE ++ Sbjct: 123 GEAQVKGTGFPADGPVMANSLTAMV----PSEEELSECFRTFDKDGDGFIDREEFGGIIR 178 Query: 129 DLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 E+ E D + D++ +G+++ E +++ Sbjct: 179 LTGEQLTD--------EDPDEIFGDSDTDKNGRIDFDEFLKMV 213 Score = 49.4 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 34/90 (37%), Gaps = 7/90 (7%) Query: 1 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKT 60 MA S L + + + + E + FD DG G+++ +E +I+ + + Sbjct: 139 MANS-LTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTD------EDPDE 191 Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLL 90 +G+I E ++ + + Sbjct: 192 IFGDSDTDKNGRIDFDEFLKMVENVQLSMA 221 Score = 47.5 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 36/85 (42%), Gaps = 8/85 (9%) Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNK 193 AN E + FD + DG ++ E ++ + G ++ ++ ++ Sbjct: 140 ANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIRLT--------GEQLTDEDPDE 191 Query: 194 AFELYDQDGNGYIDENELDALLKDL 218 F D D NG ID +E +++++ Sbjct: 192 IFGDSDTDKNGRIDFDEFLKMVENV 216 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 21/35 (60%) Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E ++ F +D+DG+G+ID E +++ E+ Sbjct: 149 SEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQ 183 Score = 33.3 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 28/74 (37%), Gaps = 9/74 (12%) Query: 56 PEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHS 115 E+ + + DG I E ++ L + E+ + + DTD + Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGIIRLTGEQL---------TDEDPDEIFGDSDTDKN 201 Query: 116 GFIETEELKNFLKD 129 G I+ +E +++ Sbjct: 202 GRIDFDEFLKMVEN 215 >1JBA-A nrPDB Length = 204 Score = 69.5 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 17/123 (13%) Query: 102 EFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 + + ++K+ + SG + E K F K D+ + +Y + M + FD+N D Sbjct: 23 QLQEWYKKFLEECPSGTLFMHEFKRFFK--------VPDNEEATQYVEAMFRAFDTNGDN 74 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ E L + L+ + F++YD+D NG ID EL +++ + + Sbjct: 75 TIDFLEYVAALNLVLRGTLEH--------KLKWTFKIYDKDRNGCIDRQELLDIVESIYK 126 Query: 221 KNK 223 K Sbjct: 127 LKK 129 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 57/168 (33%), Gaps = 25/168 (14%) Query: 12 TASQFFEIWLHFDAD-GSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 A+Q E + F + SG L E + + E + ++ + D Sbjct: 20 DAAQLQEWYKKFLEECPSGTLFMHEFKRFFKV------PDNEEATQYVEAMFRAFDTNGD 73 Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 I +E L L + T++ YD D +G I+ +EL + ++ + Sbjct: 74 NTIDFLEYVAALNLVLRGTL---------EHKLKWTFKIYDKDRNGCIDRQELLDIVESI 124 Query: 131 LEKANKTVDDTK---------LAEYTDLMLKLFDSNNDGKLELTEMAR 169 + + + E D + L D N DG+L L E Sbjct: 125 YKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVE 172 Score = 34.4 bits (77), Expect = 0.050, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 40/91 (43%), Gaps = 11/91 (12%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMK-------TFVDQY-- 65 + + +D D +G ++ +EL ++++ + + +K +E+ E + VD+ Sbjct: 96 KLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFL 155 Query: 66 --GQRDDGKIGIVELAHVLPTEENFLLLFRC 94 + DG++ + E ++ + + + Sbjct: 156 LVDENGDGQLSLNEFVEGARRDKWVMKMLQM 186 >2JUL-A nrPDB Length = 256 Score = 68.7 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 27/210 (12%), Positives = 72/210 (34%), Gaps = 24/210 (11%) Query: 44 QQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEF 103 + + L +K + + + + L + Q + +E Sbjct: 34 RPRFTRQALMRCCLIKWILSSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKEL 93 Query: 104 MKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 +R + + +G ++ + K + + T Y + FD++ +G + Sbjct: 94 QSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATT-------YAHFLFNAFDADGNGAI 146 Query: 163 ELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE-- 220 + L + + ++ AF LYD + +G I + E+ A++K + + Sbjct: 147 HFEDFVVGLSILLRGTVH--------EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 Query: 221 ------KNKQDLDINNITTYKKNIMALSDG 244 ++D + ++ + + + DG Sbjct: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDG 228 Score = 56.0 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 38/120 (31%), Gaps = 13/120 (10%) Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 + + +G I + + L + E+ + YD + G I Sbjct: 134 LFNAFDADGNGAIHFEDFV---------VGLSILLRGTVHEKLKWAFNLYDINKDGCITK 184 Query: 121 EELKNFLKD----LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 EE+ +K + + + E+ + + D N DG + + E EN Sbjct: 185 EEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDEN 244 Score = 37.1 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 42/107 (39%), Gaps = 9/107 (8%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELA 79 + FDADG+G + ++ + L + L+ + + Y DG I E+ Sbjct: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNL------YDINKDGCITKEEML 188 Query: 80 HVLPTEENFLLLFR---CQQLKSCEEFMKTWRKYDTDHSGFIETEEL 123 ++ + + + ++ E + ++K D + G + +E Sbjct: 189 AIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 Score = 33.3 bits (74), Expect = 0.098, Method: Composition-based stats. Identities = 10/85 (11%), Positives = 29/85 (34%), Gaps = 6/85 (7%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQEL------QQARKKAGLELSPEMKTFVDQYGQR 68 + + +D + G + +E+ +++ + ++ F + + Sbjct: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 Query: 69 DDGKIGIVELAHVLPTEENFLLLFR 93 DG + I E +EN + + Sbjct: 226 QDGVVTIDEFLETCQKDENIMNSMQ 250 >2RO9-A nrPDB Length = 69 Score = 68.7 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 8/77 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 S EE + +R +D D +GFI EL++ + +L EK E D M++ D + Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTD--------EEVDEMIREADVD 52 Query: 158 NDGKLELTEMARLLPVQ 174 DG++ E +++ + Sbjct: 53 GDGQINYEEFVKVMMAK 69 Score = 47.1 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 186 MCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +E +AF ++D+D NG+I EL ++ +L EK + + + DG Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDE----EVDEMIREADVDGDG 55 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 29/68 (42%), Gaps = 6/68 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + E + FD D +G++ EL++++ L + E+ + + DG+I Sbjct: 5 ELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTD------EEVDEMIREADVDGDGQIN 58 Query: 75 IVELAHVL 82 E V+ Sbjct: 59 YEEFVKVM 66 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 8/71 (11%) Query: 145 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 E ++FD + +G + E+ ++ G K+ +E ++ D DG+G Sbjct: 4 EELKEAFRVFDKDQNGFISAAELRHVMT--------NLGEKLTDEEVDEMIREADVDGDG 55 Query: 205 YIDENELDALL 215 I+ E ++ Sbjct: 56 QINYEEFVKVM 66 >2W4G-C nrPDB Length = 145 Score = 68.3 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 58/158 (36%), Gaps = 19/158 (12%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + F E +L FD G + ++ ++++ L Q A + + + Sbjct: 2 EINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEI----NKILGNPSKEEMNAK 57 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 KI E +L N + + E+F++ R +D + +G + EL++ L L Sbjct: 58 KITFEEFLPMLQAAANN------KDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLG 111 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 EK + + L +++G + + Sbjct: 112 EKMTEEEVEE---------LMKGQEDSNGCINYEAFVK 140 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 45/124 (36%), Gaps = 11/124 (8%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 +F + + +D I ++ + ++ L + + L + + Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAK--- 57 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 K+ E +L N + ++F + ++D++GNG + EL +L Sbjct: 58 ---KITFEEFLPMLQAAAN-----NKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLAT 109 Query: 218 LCEK 221 L EK Sbjct: 110 LGEK 113 >2D8N-A nrPDB Length = 207 Score = 68.3 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 51/128 (39%), Gaps = 16/128 (12%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 S EE ++ + D +G I ++ ++ DT Y + + FDSN Sbjct: 31 SEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFP-------DTDPKAYAQHVFRSFDSN 83 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 DG L+ E L + ++ AF LYD DGNG I +NE+ ++ Sbjct: 84 LDGTLDFKEYVIALHMTTAGK--------TNQKLEWAFSLYDVDGNGTISKNEVLEIVMA 135 Query: 218 LCEKNKQD 225 + + + Sbjct: 136 IFKMITPE 143 Score = 43.7 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 44/137 (32%), Gaps = 16/137 (11%) Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + DG + E + L K+ ++ + YD D +G I E+ Sbjct: 80 FDSNLDGTLDFKEYV---------IALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVL 130 Query: 125 NFLKDLLEKANKT------VDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR-LLPVQENF 177 + + + D+ + + + K F N+D KL E L +E Sbjct: 131 EIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEIL 190 Query: 178 LLKFQGIKMCGKEFNKA 194 L + ++ A Sbjct: 191 RLIQFEPQKVKEKMKNA 207 Score = 34.0 bits (76), Expect = 0.073, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 44/110 (40%), Gaps = 8/110 (7%) Query: 5 HLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQ 64 H+ ++ T + + +D DG+G + E+ ++ + + ++L P+ + ++ Sbjct: 98 HMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDENTPEK 157 Query: 65 --------YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKT 106 +G+ DD K+ E + L L + + K E+ Sbjct: 158 RAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKMKNA 207 Score = 33.3 bits (74), Expect = 0.10, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 37/110 (33%), Gaps = 11/110 (10%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 ++ FD++ G L+ KE + + LE + + Y +G I E+ Sbjct: 76 VFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSL------YDVDGNGTISKNEV 129 Query: 79 AHVLPT-----EENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL 123 ++ + L + + K W+ + + + +E Sbjct: 130 LEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEF 179 >2JU0-A nrPDB Length = 190 Score = 67.9 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 58/154 (37%), Gaps = 24/154 (15%) Query: 100 CEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 E + + + D SG + E+ K + ++ + + +FD +N Sbjct: 24 RREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPE-------DFANHLFTVFDKDN 76 Query: 159 DGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL 218 +G + E +L L+ ++ + AFELYD + +GYI +E+ ++ + Sbjct: 77 NGFIHFEEFITVLSTTSRGTLE--------EKLSWAFELYDLNHDGYITFDEMLTIVASV 128 Query: 219 CEKNKQDLDIN--------NITTYKKNIMALSDG 244 + + +N + K + DG Sbjct: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDG 162 Score = 59.5 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 31/136 (22%), Positives = 54/136 (39%), Gaps = 13/136 (9%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMK-TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDD 140 L E+ + + S E+F + +D D++GFI EE L T Sbjct: 43 LAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVL--------STTSR 94 Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLL----PVQENFLLKFQGIKMCGKEFNKAFE 196 L E +L+D N+DG + EM ++ + + + + K F+ Sbjct: 95 GTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFK 154 Query: 197 LYDQDGNGYIDENELD 212 L D++ +GYI +E Sbjct: 155 LMDKNEDGYITLDEFR 170 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 39/111 (35%), Gaps = 13/111 (11%) Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 + + ++G I E VL T L E+ + YD +H G+I Sbjct: 68 LFTVFDKDNNGFIHFEEFITVLSTTSRGTL---------EEKLSWAFELYDLNHDGYITF 118 Query: 121 EEL----KNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 +E+ + K + D+ + KL D N DG + L E Sbjct: 119 DEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEF 169 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 39/109 (35%), Gaps = 9/109 (8%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELA 79 + FD D +G++ +E ++ + + L + E+ Y DG I E+ Sbjct: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFEL------YDLNHDGYITFDEML 122 Query: 80 HVLPTEENFLLLFRCQQLKSCE---EFMKTWRKYDTDHSGFIETEELKN 125 ++ + + K ++ D + G+I +E + Sbjct: 123 TIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 Score = 29.0 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 26/68 (38%), Gaps = 6/68 (8%) Query: 19 IWLHFDADGSGYLEGKELQNLI----QELQQARKKAGLELSPEM--KTFVDQYGQRDDGK 72 + +D + GY+ E+ ++ + + E +PEM K + +DG Sbjct: 104 AFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGY 163 Query: 73 IGIVELAH 80 I + E Sbjct: 164 ITLDEFRE 171 >3J04-B nrPDB Length = 143 Score = 67.5 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 22/160 (13%), Positives = 52/160 (32%), Gaps = 26/160 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 +F E + D + G+++ ++L +++ + + +++ G Sbjct: 6 IQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPT----------DEYLEGMMSEAPGP 55 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I + + N + + +D + SGFI + L+ L + + Sbjct: 56 INFTMFLTMFGEKLN--------GTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGD 107 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 + E D M + + G E R+L Sbjct: 108 RFTD--------EEVDEMYREAPIDKKGNFNYVEFTRILK 139 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 47/126 (37%), Gaps = 19/126 (15%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 +EF + + D + GFI+ E+L + L + + EY + M+ Sbjct: 2 DQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTD--------EYLEGMMSEA- 52 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 G + T + + N AF +D++ +G+I E+ L LL Sbjct: 53 ---PGPINFTMFLTMFGEKLNGT-------DPEDVIRNAFACFDEEASGFIHEDHLRELL 102 Query: 216 KDLCEK 221 + ++ Sbjct: 103 TTMGDR 108 >1TNP-A nrPDB Length = 90 Score = 67.5 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 8/85 (9%) Query: 2 AESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTF 61 A + L +I ++F + FDADG G + KEL +++ L Q K E+ Sbjct: 10 ARAFLSEEMI--AEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK------EELDAI 61 Query: 62 VDQYGQRDDGKIGIVELAHVLPTEE 86 +++ + G I E ++ + Sbjct: 62 IEEVDEDGSGTIDFEEFLVMMVRQM 86 Score = 55.6 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 8/75 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + +D D G I T+EL ++ L + K E D +++ D + G Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK--------EELDAIIEEVDEDGSGT 72 Query: 162 LELTEMARLLPVQEN 176 ++ E ++ Q Sbjct: 73 IDFEEFLVMMVRQMK 87 Score = 27.9 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 26/76 (34%), Gaps = 9/76 (11%) Query: 52 LELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYD 111 E+ E K D + G I EL V+ Q + EE + D Sbjct: 16 EEMIAEFKAAFDMFDADGGGDISTKELGTVM---------RMLGQNPTKEELDAIIEEVD 66 Query: 112 TDHSGFIETEELKNFL 127 D SG I+ EE + Sbjct: 67 EDGSGTIDFEEFLVMM 82 Score = 27.5 bits (59), Expect = 6.1, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 EF AF+++D DG G I EL +++ L + Sbjct: 20 AEFKAAFDMFDADGGGDISTKELGTVMRMLGQ 51 >2L2E-A nrPDB Length = 190 Score = 67.5 bits (163), Expect = 6e-12, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 53/152 (34%), Gaps = 24/152 (15%) Query: 102 EFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E + ++ + D SG + E + K + + + + +FD++ +G Sbjct: 26 ELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFG-------DPSAFAEYVFNVFDADKNG 78 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ E L V L + AF+LYD D NG I +E+ ++ + + Sbjct: 79 YIDFKEFICALSVTSRGELN--------DKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 Query: 221 KNKQDLDI--------NNITTYKKNIMALSDG 244 + + + + DG Sbjct: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDG 162 Score = 50.6 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 59/169 (34%), Gaps = 19/169 (11%) Query: 6 LQSSLITASQFFEIWLHFDAD-GSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQ 64 ++S+ + + + F D SG+L E Q + ++ + + + Sbjct: 17 VRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFA-----EYVFNV 71 Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + +G I E L L ++ + ++ YD D++G I +E+ Sbjct: 72 FDADKNGYIDFKEFICALSVTSRGEL---------NDKLIWAFQLYDLDNNGLISYDEML 122 Query: 125 NF----LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 K + D+ + + + + D N DG+L L E Sbjct: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 45/108 (41%), Gaps = 12/108 (11%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 + +D D +G+I+ +E A +L + +L+D +N+G + E Sbjct: 69 FNVFDADKNGYIDFKEF--------ICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDE 120 Query: 167 MARLL----PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 M R++ + + + + K NK F + D++ +G + E Sbjct: 121 MLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEE 168 >1TRF-A nrPDB Length = 76 Score = 66.8 bits (161), Expect = 8e-12, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 8/83 (9%) Query: 4 SHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVD 63 + L +I ++F + FDADG G + KEL +++ L Q K E+ ++ Sbjct: 1 AFLSEEMI--AEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK------EELDAIIE 52 Query: 64 QYGQRDDGKIGIVELAHVLPTEE 86 + + G I E ++ + Sbjct: 53 EVDEDGSGTIDFEEFLVMMVRQM 75 Score = 57.1 bits (136), Expect = 8e-09, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 8/75 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + +D D G I T+EL ++ L + K E D +++ D + G Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTK--------EELDAIIEEVDEDGSGT 61 Query: 162 LELTEMARLLPVQEN 176 ++ E ++ Q Sbjct: 62 IDFEEFLVMMVRQMK 76 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 26/76 (34%), Gaps = 9/76 (11%) Query: 52 LELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYD 111 E+ E K D + G I EL V+ Q + EE + D Sbjct: 5 EEMIAEFKAAFDMFDADGGGDISTKELGTVM---------RMLGQNPTKEELDAIIEEVD 55 Query: 112 TDHSGFIETEELKNFL 127 D SG I+ EE + Sbjct: 56 EDGSGTIDFEEFLVMM 71 Score = 28.3 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 EF AF+++D DG G I EL +++ L + Sbjct: 9 AEFKAAFDMFDADGGGDISTKELGTVMRMLGQ 40 >2LV7-A nrPDB Length = 100 Score = 66.8 bits (161), Expect = 9e-12, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 35/76 (46%), Gaps = 8/76 (10%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 EE + ++ +D D +GFI +EL ++ L N+ +++++ D Sbjct: 31 PEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEV--------ELEVIIQRLD 82 Query: 156 SNNDGKLELTEMARLL 171 + DG+++ E LL Sbjct: 83 MDGDGQVDFEEFVTLL 98 Score = 58.7 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + E + FD DG+G++ +EL ++ L + LE+ + + DG Sbjct: 34 ELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEV------IIQRLDMDGDG 87 Query: 72 KIGIVELAHVL 82 ++ E +L Sbjct: 88 QVDFEEFVTLL 98 Score = 43.7 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 23/35 (65%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 + +E +AF+++D+DGNG+I + EL ++ L Sbjct: 32 EDELEEIREAFKVFDRDGNGFISKQELGTAMRSLG 66 Score = 34.0 bits (76), Expect = 0.066, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 30/87 (34%), Gaps = 8/87 (9%) Query: 129 DLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCG 188 +LL + E K+FD + +G + E+ + + G Sbjct: 20 NLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAM--------RSLGYMPNE 71 Query: 189 KEFNKAFELYDQDGNGYIDENELDALL 215 E + D DG+G +D E LL Sbjct: 72 VELEVIIQRLDMDGDGQVDFEEFVTLL 98 Score = 31.3 bits (69), Expect = 0.43, Method: Composition-based stats. Identities = 11/83 (13%), Positives = 26/83 (31%), Gaps = 9/83 (10%) Query: 45 QARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFM 104 Q + E++ + + +G + +E + + + E Sbjct: 25 QRPVDIPEDELEEIREAFKVFDRDGNG---------FISKQELGTAMRSLGYMPNEVELE 75 Query: 105 KTWRKYDTDHSGFIETEELKNFL 127 ++ D D G ++ EE L Sbjct: 76 VIIQRLDMDGDGQVDFEEFVTLL 98 >5H53-C nrPDB Length = 153 Score = 66.8 bits (161), Expect = 9e-12, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 50/130 (38%), Gaps = 11/130 (8%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + +EF + + YD I ++ + L+ L L ++ + Sbjct: 6 SKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAK- 64 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 K+E + +L N + ++F + ++D++GNG + EL +L Sbjct: 65 -----KIEFEQFLPMLQAISN-----NKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVL 114 Query: 216 KDLCEKNKQD 225 L EK K++ Sbjct: 115 ATLGEKMKEE 124 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 59/155 (38%), Gaps = 19/155 (12%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 +F E +L +D G + ++ ++++ L A ++ + + + KI Sbjct: 12 EFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPS----NEEMNAKKIE 67 Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKA 134 + +L N + + E+F++ R +D + +G + EL++ L L E Sbjct: 68 FEQFLPMLQAISNN------KDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE-- 119 Query: 135 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 K+ E L +++G + + Sbjct: 120 -------KMKEEEVEALMAGQEDSNGCINYEAFVK 147 Score = 33.3 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 7/69 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T F E FD +G+G + G EL++++ L + K+ +E + + +G Sbjct: 86 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEA-------LMAGQEDSNG 138 Query: 72 KIGIVELAH 80 I Sbjct: 139 CINYEAFVK 147 Score = 27.1 bits (58), Expect = 8.1, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 23/41 (56%) Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 +K + K EF +AF LYD+ G+ I +++ +L+ L Sbjct: 1 IKIEFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALG 41 >2ROB-A nrPDB Length = 70 Score = 66.0 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 37/74 (50%), Gaps = 8/74 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + EE + ++ +D D +G+I EL++ + +L EK E + M+K D + Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTD--------EEVEQMIKEADLD 52 Query: 158 NDGKLELTEMARLL 171 DG++ E +++ Sbjct: 53 GDGQVNYEEFVKMM 66 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 4/59 (6%) Query: 186 MCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +E +AF+++D+D NGYI +EL ++ +L EK + + K DG Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDE----EVEQMIKEADLDGDG 55 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 30/68 (44%), Gaps = 6/68 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + E + FD D +GY+ EL++++ L + E++ + + DG++ Sbjct: 5 ELKEAFKVFDKDQNGYISASELRHVMINLGEKLTD------EEVEQMIKEADLDGDGQVN 58 Query: 75 IVELAHVL 82 E ++ Sbjct: 59 YEEFVKMM 66 Score = 27.9 bits (60), Expect = 4.8, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 32/75 (42%), Gaps = 8/75 (10%) Query: 145 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 E K+FD + +G + +E+ ++ G K+ +E + + D DG+G Sbjct: 4 EELKEAFKVFDKDQNGYISASELRHVM--------INLGEKLTDEEVEQMIKEADLDGDG 55 Query: 205 YIDENELDALLKDLC 219 ++ E ++ + Sbjct: 56 QVNYEEFVKMMMTVR 70 >2GGZ-A nrPDB Length = 211 Score = 65.2 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 16/140 (11%) Query: 87 NFLLLFRCQQLKSCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAE 145 N + Q+ +E +R + + SG E K L K + Sbjct: 5 NGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLN-------QKANK 57 Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 + D + FD+N DG ++ E + + ++ ++ F+LYD DGNG Sbjct: 58 HIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKME--------QKLKWYFKLYDADGNGS 109 Query: 206 IDENELDALLKDLCEKNKQD 225 ID+NEL + + N Q Sbjct: 110 IDKNELLDMFMAVQALNGQQ 129 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 26/151 (17%), Positives = 54/151 (35%), Gaps = 16/151 (10%) Query: 28 SGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEEN 87 SG E + L+ + + + + + + DG + +E + Sbjct: 34 SGLQTLHEFKTLL-----GLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQ 88 Query: 88 FLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYT 147 + ++ ++ YD D +G I+ EL + + +A E+ Sbjct: 89 EKM---------EQKLKWYFKLYDADGNGSIDKNELLDMF--MAVQALNGQQTLSPEEFI 137 Query: 148 DLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 +L+ D NNDG+L L E + ++ L Sbjct: 138 NLVFHKIDINNDGELTLEEFINGMAKDQDLL 168 Score = 37.1 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 35/80 (43%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + + +DADG+G ++ EL ++ +Q + L + + +DG++ Sbjct: 93 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 152 Query: 74 GIVELAHVLPTEENFLLLFR 93 + E + + +++ L + Sbjct: 153 TLEEFINGMAKDQDLLEIVY 172 >5B8I-B nrPDB Length = 171 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 57/156 (36%), Gaps = 21/156 (13%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELA 79 ++ D D SG +E E +L Q + +P + + + G + E Sbjct: 27 FMKLDRDKSGTIERDEFLSLPQ----------VSSNPLSTRMIAIFDEDGGGDVDFQEFV 76 Query: 80 HVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD 139 L + + E+ ++ YD D GFI EL LK + + Sbjct: 77 SGLSAFSS--------KGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMM---VGSNLK 125 Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQE 175 D +L + D + D + DG++ E R++ + Sbjct: 126 DMQLQQIVDKTIMEADLDGDGRISFEEFTRMVENTD 161 Score = 56.8 bits (135), Expect = 8e-09, Method: Composition-based stats. Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 20/145 (13%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 + K + K D D SG IE +E ++ + M+ +FD + G Sbjct: 21 DRLWKRFMKLDRDKSGTIERDEF------------LSLPQVSSNPLSTRMIAIFDEDGGG 68 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ E + L F ++ AF++YD D +G+I EL +LK + Sbjct: 69 DVDFQEFV-------SGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVG 121 Query: 221 KNKQDLDINNI-TTYKKNIMALSDG 244 N +D+ + I DG Sbjct: 122 SNLKDMQLQQIVDKTIMEADLDGDG 146 Score = 37.5 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 30/77 (38%), Gaps = 1/77 (1%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 + +D D G++ EL +++ + ++L + + + DG+I E Sbjct: 95 AFKVYDIDRDGFISNGELFIVLKMM-VGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEF 153 Query: 79 AHVLPTEENFLLLFRCQ 95 ++ + + + Q Sbjct: 154 TRMVENTDVSMSMTLDQ 170 Score = 30.2 bits (66), Expect = 0.97, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 41/118 (34%), Gaps = 9/118 (7%) Query: 23 FDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 82 FD DG G ++ +E + + K +++ Y DG I EL VL Sbjct: 62 FDEDGGGDVDFQEFVSGLSAFSSKGNK-----EEKLRFAFKVYDIDRDGFISNGELFIVL 116 Query: 83 PTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDD 140 L Q + M+ D D G I EE +++ + T+D Sbjct: 117 KMMVGSNLKDMQLQQIVDKTIMEA----DLDGDGRISFEEFTRMVENTDVSMSMTLDQ 170 >1N2D-A nrPDB Length = 148 Score = 64.9 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 23/158 (14%), Positives = 56/158 (35%), Gaps = 16/158 (10%) Query: 17 FEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIV 76 +I+ FD G G + L + ++ + ++ + + + Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASS--------L 58 Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 L + E E+F+K ++ +D + +G + +L+ L L EK Sbjct: 59 TLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTD 118 Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 D +LK + +++G+++ + + Q Sbjct: 119 A--------EVDELLKGVEVDSNGEIDYKKFIEDVLRQ 148 Score = 44.0 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 48/118 (40%), Gaps = 9/118 (7%) Query: 104 MKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLE 163 + +D G I + L ++L+ + + D++ + L Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQL-------VQDIINADSSLRDASSLT 59 Query: 164 LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 L ++ L+ V E L K ++F KAF+++D++ G + +L +L L EK Sbjct: 60 LDQITGLIEVNEKEL--DATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEK 115 Score = 34.4 bits (77), Expect = 0.046, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 27/71 (38%), Gaps = 6/71 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 F + + FD + +G + +L+ ++ L + A E+ + +G+I Sbjct: 84 DFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDA------EVDELLKGVEVDSNGEID 137 Query: 75 IVELAHVLPTE 85 + + + Sbjct: 138 YKKFIEDVLRQ 148 >6FSA-D nrPDB Length = 199 Score = 62.9 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 56/159 (35%), Gaps = 21/159 (13%) Query: 13 ASQFFEIWLHFDADGSG--YLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 +F E + FD + + ++++ L Q +A + + + Sbjct: 55 IEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQ----EELNS 110 Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 + +L + + + + E+F++ R +D + +G + EL++ L L Sbjct: 111 KMMDFDTFLPMLQH------ISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 164 Query: 131 LEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 EK + E LM DSN G + + Sbjct: 165 GEKLTE-------DEVEKLMAGQEDSN--GCINYEAFVK 194 Score = 57.9 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 46/127 (36%), Gaps = 13/127 (10%) Query: 101 EEFMKTWRKYDTDH--SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 EEF + + +D I + + L+ L + + L + L N Sbjct: 56 EEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEEL------N 109 Query: 159 DGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL 218 ++ +L + ++F + ++D++GNG + EL +L L Sbjct: 110 SKMMDFDTFLPMLQ-----HISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 164 Query: 219 CEKNKQD 225 EK +D Sbjct: 165 GEKLTED 171 Score = 36.0 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 27/69 (39%), Gaps = 7/69 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T F E FD +G+G + G EL++++ L + + +E + + +G Sbjct: 133 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKLTEDEVEK-------LMAGQEDSNG 185 Query: 72 KIGIVELAH 80 I Sbjct: 186 CINYEAFVK 194 >3DD4-A nrPDB Length = 229 Score = 62.5 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 77/199 (38%), Gaps = 27/199 (13%) Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPT---EENFLLLFRCQQLKSCEEFMKTWRKYDTD- 113 ++Q+G + G VE + T L L Q + +E +R + + Sbjct: 18 FVKLLEQFGLIEAGLEDSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNEC 77 Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 SG + E K + + T Y + FD++++G + + + L + Sbjct: 78 PSGVVNEETFKEIYSQFFPQGDSTT-------YAHFLFNAFDTDHNGAVSFEDFIKGLSI 130 Query: 174 QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKN--------KQD 225 ++ ++ N AF LYD + +GYI + E+ ++K + + K+D Sbjct: 131 LLRGTVQ--------EKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKED 182 Query: 226 LDINNITTYKKNIMALSDG 244 ++ T+ + + DG Sbjct: 183 APRQHVETFFQKMDKNKDG 201 Score = 50.2 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 17/120 (14%), Positives = 40/120 (33%), Gaps = 13/120 (10%) Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 + + +G + + L + E+ + YD + G+I Sbjct: 107 LFNAFDTDHNGAVSFEDFI---------KGLSILLRGTVQEKLNWAFNLYDINKDGYITK 157 Query: 121 EELKNFLKD----LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 EE+ + +K + + + + ++ + + D N DG + + E EN Sbjct: 158 EEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDEN 217 Score = 31.0 bits (68), Expect = 0.49, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 31/81 (38%), Gaps = 6/81 (7%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQA------RKKAGLELSPEMKTFVDQYGQRDDGK 72 + +D + GY+ +E+ ++++ + ++TF + + DG Sbjct: 143 AFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGV 202 Query: 73 IGIVELAHVLPTEENFLLLFR 93 + I E +EN + + Sbjct: 203 VTIDEFIESCQKDENIMRSMQ 223 >2KSZ-A nrPDB Length = 76 Score = 62.2 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 30/71 (42%), Gaps = 6/71 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 F E + FD DG G + +EL +I+ L Q + E++ + + +G I Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE------EELQDMISEVDADGNGTIE 64 Query: 75 IVELAHVLPTE 85 E ++ + Sbjct: 65 FDEFLSLMAKK 75 Score = 54.8 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 +F + + +D D G I EEL ++ L + + E M+ D++ +G Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTE--------EELQDMISEVDADGNGT 62 Query: 162 LELTEMARLLPVQ 174 +E E L+ + Sbjct: 63 IEFDEFLSLMAKK 75 Score = 31.7 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +F +AF L+D+DG+G I EL +++ L + ++ + + A +G Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEE----ELQDMISEVDADGNG 61 Score = 28.6 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 28/69 (40%), Gaps = 8/69 (11%) Query: 148 DLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYID 207 LFD + DG + + E+A ++ + +E D DGNG I+ Sbjct: 13 KEAFGLFDKDGDGCITVEELATVI--------RSLDQNPTEEELQDMISEVDADGNGTIE 64 Query: 208 ENELDALLK 216 +E +L+ Sbjct: 65 FDEFLSLMA 73 Score = 28.3 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 28/71 (39%), Gaps = 9/71 (12%) Query: 57 EMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116 + K + + DG I + ELA V+ Q + EE + D D +G Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVI---------RSLDQNPTEEELQDMISEVDADGNG 61 Query: 117 FIETEELKNFL 127 IE +E + + Sbjct: 62 TIEFDEFLSLM 72 >5TBY-C nrPDB Length = 195 Score = 61.0 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 31/163 (19%), Positives = 60/163 (36%), Gaps = 29/163 (17%) Query: 13 ASQFFEIWLHFDADGSG--YLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 +F E ++ FD + + ++++ L Q +A + Sbjct: 51 IEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVL-------------- 96 Query: 71 GKIGIVELAHVLPTEENFLLLF----RCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 126 GK EL + E FL + + + + E+F++ R +D + +G + EL++ Sbjct: 97 GKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHV 156 Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 L L E+ + E LM DSN G + + Sbjct: 157 LATLGERLTE-------DEVEKLMAGQEDSN--GCINYEAFVK 190 Score = 55.2 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 46/127 (36%), Gaps = 13/127 (10%) Query: 101 EEFMKTWRKYDTDH--SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 EEF + + +D I + + L+ L + + L + L N Sbjct: 52 EEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEEL------N 105 Query: 159 DGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL 218 ++ +L + ++F + ++D++GNG + EL +L L Sbjct: 106 TKMMDFETFLPMLQ-----HISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATL 160 Query: 219 CEKNKQD 225 E+ +D Sbjct: 161 GERLTED 167 Score = 35.2 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 27/69 (39%), Gaps = 7/69 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T F E FD +G+G + G EL++++ L + + +E + + +G Sbjct: 129 TYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEK-------LMAGQEDSNG 181 Query: 72 KIGIVELAH 80 I Sbjct: 182 CINYEAFVK 190 >3JBH-C nrPDB Length = 156 Score = 60.6 bits (145), Expect = 7e-10, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 68/155 (43%), Gaps = 21/155 (13%) Query: 17 FEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIV 76 E + +D +G G ++ ++L +L++ L A ++ + +R + K+ + Sbjct: 13 REHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKNG-------GSDKRGEKKLTLE 65 Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 E + F + + +++ + E+FM+ + YD +G + EL + L L E+ Sbjct: 66 EFLPI------FSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTD 119 Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + ++++ D ++DG L+ + + Sbjct: 120 I--------ECEEIMRVCDEDDDGFLKYEPFVKTI 146 Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 48/130 (36%), Gaps = 14/130 (10%) Query: 92 FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 151 + E+ + + YD + G I+ +L + L+ L K + Sbjct: 1 MADLKAAEVEKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKNGG------- 53 Query: 152 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 D + KL L E + +K + ++F + ++YD+ NG + EL Sbjct: 54 --SDKRGEKKLTLEEFLPIFS-----QIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAEL 106 Query: 212 DALLKDLCEK 221 +L L E+ Sbjct: 107 AHVLLSLGER 116 Score = 28.6 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 12/76 (15%), Positives = 26/76 (34%), Gaps = 6/76 (7%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + + T F E +D +G + EL +++ L + E + + Sbjct: 77 EKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDI------ECEEIMRVCD 130 Query: 67 QRDDGKIGIVELAHVL 82 + DDG + + Sbjct: 131 EDDDGFLKYEPFVKTI 146 >2AMI-A nrPDB Length = 96 Score = 60.2 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 6/73 (8%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FD DGSG ++ KEL+ ++ L KK E+K + + + G I Sbjct: 30 QEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK------EEIKKMISEIDKDGSGTI 83 Query: 74 GIVELAHVLPTEE 86 E ++ + Sbjct: 84 DFEEFLTMMTAKM 96 Score = 57.1 bits (136), Expect = 8e-09, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 34/78 (43%), Gaps = 8/78 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +DTD SG I+ +ELK ++ L + K E M+ D + Sbjct: 27 EQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKK--------EEIKKMISEIDKD 78 Query: 158 NDGKLELTEMARLLPVQE 175 G ++ E ++ + Sbjct: 79 GSGTIDFEEFLTMMTAKM 96 Score = 37.5 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 34/85 (40%), Gaps = 4/85 (4%) Query: 160 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 G + + ++ + + +E +AF+L+D DG+G ID EL ++ L Sbjct: 1 GSMSYKAKTVVSARRDQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALG 60 Query: 220 EKNKQDLDINNITTYKKNIMALSDG 244 + K++ I I G Sbjct: 61 FEPKKE----EIKKMISEIDKDGSG 81 Score = 34.8 bits (78), Expect = 0.037, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 35/103 (33%), Gaps = 9/103 (8%) Query: 27 GSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEE 86 GS + K + + ++ ++ R E E++ D + G I EL + Sbjct: 1 GSMSYKAKTVVSARRDQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAM---- 56 Query: 87 NFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 EE K + D D SG I+ EE + Sbjct: 57 -----RALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTA 94 Score = 32.1 bits (71), Expect = 0.25, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 30/77 (38%), Gaps = 8/77 (10%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 + + LFD++ G ++ E+ + + G + +E K D+ Sbjct: 26 EEQKQEIREAFDLFDTDGSGTIDAKELKVAM--------RALGFEPKKEEIKKMISEIDK 77 Query: 201 DGNGYIDENELDALLKD 217 DG+G ID E ++ Sbjct: 78 DGSGTIDFEEFLTMMTA 94 >3AAJ-A nrPDB Length = 167 Score = 60.2 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 32/195 (16%), Positives = 64/195 (32%), Gaps = 44/195 (22%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 S + ++ D D SG + ELQ + +++ + + + + Sbjct: 2 DQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFN-----PVTVRSIISMFDRENKA 56 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 + E V K ++ +R YD D+SG I+ ELK L Sbjct: 57 GVNFSEFTGVW---------------KYITDWQNVFRTYDRDNSGMIDKNELKQALSGYR 101 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEF 191 ++ D++++ FD G++ + + + + Sbjct: 102 LS----------DQFHDILIRKFDRQGRGQIAFDDFIQ--------------GCIVLQRL 137 Query: 192 NKAFELYDQDGNGYI 206 F YD D +G+I Sbjct: 138 TDIFRRYDTDQDGWI 152 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 40/110 (36%), Gaps = 21/110 (19%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 +++ D D SG I EL+ L + V ++ +FD N + +E Sbjct: 10 FQRVDKDRSGVISDTELQQALSNGTWTPFNPVT-------VRSIISMFDRENKAGVNFSE 62 Query: 167 MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 + ++ F YD+D +G ID+NEL L Sbjct: 63 FTGVWKYIT--------------DWQNVFRTYDRDNSGMIDKNELKQALS 98 >2B1U-A nrPDB Length = 71 Score = 59.8 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E+ +R +D D G I +EL+ + L + E D M++ D + DG Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPL--------PQEELDAMIREADVDQDG 57 Query: 161 KLELTEMARLLP 172 ++ E AR+L Sbjct: 58 RVNYEEFARMLA 69 Score = 47.1 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 27/73 (36%), Gaps = 6/73 (8%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + FD DG G++ EL+ + L Q E+ + + DG+ Sbjct: 5 LEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPL------PQEELDAMIREADVDQDGR 58 Query: 73 IGIVELAHVLPTE 85 + E A +L E Sbjct: 59 VNYEEFARMLAQE 71 Score = 36.7 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 25/56 (44%), Gaps = 4/56 (7%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 ++ AF +DQDG+G+I +EL + L + Q+ + + DG Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQE----ELDAMIREADVDQDG 57 Score = 31.3 bits (69), Expect = 0.41, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 28/72 (38%), Gaps = 8/72 (11%) Query: 145 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 E + + FD + DG + + E+ R + G + +E + D D +G Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMA--------GLGQPLPQEELDAMIREADVDQDG 57 Query: 205 YIDENELDALLK 216 ++ E +L Sbjct: 58 RVNYEEFARMLA 69 Score = 28.3 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 24/72 (33%), Gaps = 9/72 (12%) Query: 56 PEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHS 115 +++ + Q DG I + EL + L EE R+ D D Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPL---------PQEELDAMIREADVDQD 56 Query: 116 GFIETEELKNFL 127 G + EE L Sbjct: 57 GRVNYEEFARML 68 >5B7X-A nrPDB Length = 156 Score = 59.1 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 23/150 (15%), Positives = 58/150 (38%), Gaps = 14/150 (9%) Query: 6 LQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQY 65 +++ + + + +D D G ++ K+L LI+ L A + E+ +++ ++ Sbjct: 5 IEAPNANTQKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTED------EVNSYIKEF 58 Query: 66 GQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 + I + ++ E++ + + K + +D D G I+ +L + Sbjct: 59 AIEGE-TFQIEQFELIMEREQS-------KPDTREIKLRKAFEVFDQDKDGKIKASDLAH 110 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 L + +K K + + M D Sbjct: 111 NLTTVGDKMTKEEVEKVFSILGITMESDID 140 Score = 55.6 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 54/131 (41%), Gaps = 15/131 (11%) Query: 95 QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLF 154 + ++ + YD D+ G I+ ++L ++ L + + + +K F Sbjct: 7 APNANTQKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTE--------DEVNSYIKEF 58 Query: 155 DSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 + ++ + ++ +++ + KAFE++DQD +G I ++L Sbjct: 59 AIEGE-TFQIEQFELIMEREQS------KPDTREIKLRKAFEVFDQDKDGKIKASDLAHN 111 Query: 215 LKDLCEKNKQD 225 L + +K ++ Sbjct: 112 LTTVGDKMTKE 122 >1JC2-A nrPDB Length = 76 Score = 59.1 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 8/80 (10%) Query: 92 FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 151 + KS EE +R +D + GFI+ EEL L+ E + E + ++ Sbjct: 1 MEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHV--------IEEDIEDLM 52 Query: 152 KLFDSNNDGKLELTEMARLL 171 K D NNDG+++ E +++ Sbjct: 53 KDSDKNNDGRIDFDEFLKMM 72 Score = 35.2 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 9/68 (13%), Positives = 29/68 (42%), Gaps = 6/68 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + + FD + G+++ +EL +++ + +++ + + +DG+I Sbjct: 11 ELANCFRIFDKNADGFIDIEELGEILRATG------EHVIEEDIEDLMKDSDKNNDGRID 64 Query: 75 IVELAHVL 82 E ++ Sbjct: 65 FDEFLKMM 72 Score = 31.7 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 4/58 (6%) Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +E F ++D++ +G+ID EL +L+ E ++ +I K+ +DG Sbjct: 8 SEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEE----DIEDLMKDSDKNNDG 61 Score = 30.2 bits (66), Expect = 0.86, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 8/76 (10%) Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD 199 K E ++FD N DG +++ E+ +L G + ++ + D Sbjct: 5 KGKSEEELANCFRIFDKNADGFIDIEELGEILRAT--------GEHVIEEDIEDLMKDSD 56 Query: 200 QDGNGYIDENELDALL 215 ++ +G ID +E ++ Sbjct: 57 KNNDGRIDFDEFLKMM 72 >4ZCV-A nrPDB Length = 165 Score = 58.3 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 49/126 (38%), Gaps = 21/126 (16%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 CQ + + ++ D + G ++ EL+ L++L + + + Sbjct: 6 CQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLG--------QDAEEKIFTT 57 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 D N DGKL+ E + L K+ AF+ D++ +G I+ +E+ Sbjct: 58 GDVNKDGKLDFEEFMKYLK-------------DHEKKMKLAFKSLDKNNDGKIEASEIVQ 104 Query: 214 LLKDLC 219 L+ L Sbjct: 105 SLQTLG 110 Score = 47.9 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 24/153 (15%), Positives = 53/153 (34%), Gaps = 28/153 (18%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 +++ ++ D +G G ++ ELQ ++ L + E DGK+ Sbjct: 13 TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEE------KIFTTGDVNKDGKL 66 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E L ++ ++ D ++ G IE E+ L+ L Sbjct: 67 DFEEFMKYL--------------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLT 112 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 ++ + +L+L+ D + ++ E Sbjct: 113 ISE--------QQAELILQSIDVDGTMTVDWNE 137 >1OQP-A nrPDB Length = 77 Score = 58.3 bits (139), Expect = 4e-09, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + S EE +K +R +D D+SG I ++L+ K+L E + E M+ D Sbjct: 4 ERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTE--------EELQEMIAEAD 55 Query: 156 SNNDGKLELTEMARLLPVQENF 177 N+D +++ E R++ F Sbjct: 56 RNDDNEIDEDEFIRIMKKTSLF 77 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + + + FD D SG + K+L+ + +EL + + E++ + + + DD +I Sbjct: 10 EILKAFRLFDDDNSGTITIKDLRRVAKELGENLTE------EELQEMIAEADRNDDNEID 63 Query: 75 IVELAHVLPTEENF 88 E ++ F Sbjct: 64 EDEFIRIMKKTSLF 77 Score = 30.2 bits (66), Expect = 0.90, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 23/45 (51%) Query: 181 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQD 225 G + +E KAF L+D D +G I +L + K+L E ++ Sbjct: 1 GSGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEE 45 >2NLN-A nrPDB Length = 108 Score = 58.3 bits (139), Expect = 4e-09, Method: Composition-based stats. Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQR 68 S ++ASQ +I+ D D SGYL+G EL+ +Q+ Q ++ E K+ +D Sbjct: 36 SKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTE---SETKSLMDAADND 92 Query: 69 DDGKIGIVELAHVL 82 DGKIG E ++ Sbjct: 93 GDGKIGADEFQEMV 106 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S + +R D D SG+++ +ELK FL+ A + + T ++ D++ Sbjct: 39 SASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESE-----TKSLMDAADNDG 93 Query: 159 DGKLELTEMARLL 171 DGK+ E ++ Sbjct: 94 DGKIGADEFQEMV 106 >2BEC-A nrPDB Length = 202 Score = 57.5 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 51/164 (31%), Gaps = 21/164 (12%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELA 79 + D + GYL +LQ + L ++P ++ + ++ Sbjct: 35 FRALDRNKKGYLSRMDLQQI----------GALAVNPLGDRIIESFFPDGSQRVDFPGFV 84 Query: 80 HVLPTEENFLLLFRCQQLKSCEE--------FMKTWRKYDTDHSGFIETEELKNFLKDLL 131 VL Q E ++ YD D G I E+ L+ + Sbjct: 85 RVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLM- 143 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQE 175 V + +L D ++ D + DG + E + L + Sbjct: 144 --VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLEKMD 185 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 53/160 (33%), Gaps = 22/160 (13%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 S +R D + G++ +L+ + D +++ F Sbjct: 24 SQASLLRLHHRFRALDRNKKGYLSRMDLQQI------------GALAVNPLGDRIIESFF 71 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGK---------EFNKAFELYDQDGNGYI 206 + +++ R+L + + K + + AF+LYD D +G I Sbjct: 72 PDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDGKI 131 Query: 207 DENELDALLKDLCEKNKQDLDINNI-TTYKKNIMALSDGG 245 +E+ +L+ + + + NI + DG Sbjct: 132 SRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGA 171 Score = 39.4 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 26/73 (35%), Gaps = 1/73 (1%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 + +D D G + E+ +++ L + +L V + + DG + VE Sbjct: 119 AFQLYDLDRDGKISRHEMLQVLR-LMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEF 177 Query: 79 AHVLPTEENFLLL 91 L + + Sbjct: 178 TKSLEKMDVEQKM 190 >4N5X-A nrPDB Length = 199 Score = 56.8 bits (135), Expect = 9e-09, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 48/125 (38%), Gaps = 21/125 (16%) Query: 95 QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLF 154 Q + + ++ D + G ++ EL+ L++L + + + Sbjct: 16 QDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLG--------QDAEEKIFTTG 67 Query: 155 DSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 D N DGKL+ E + L K+ AF+ D++ +G I+ +E+ Sbjct: 68 DVNKDGKLDFEEFMKYLK-------------DHEKKMKLAFKSLDKNNDGKIEASEIVQS 114 Query: 215 LKDLC 219 L+ L Sbjct: 115 LQTLG 119 Score = 48.3 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 24/153 (15%), Positives = 53/153 (34%), Gaps = 28/153 (18%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 +++ ++ D +G G ++ ELQ ++ L + E DGK+ Sbjct: 22 TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEE------KIFTTGDVNKDGKL 75 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 E L ++ ++ D ++ G IE E+ L+ L Sbjct: 76 DFEEFMKYL--------------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLT 121 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 ++ + +L+L+ D + ++ E Sbjct: 122 ISE--------QQAELILQSIDVDGTMTVDWNE 146 >2K7C-A nrPDB Length = 72 Score = 56.8 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 7/72 (9%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 E +R++DT+ G I T EL+ ++ LL D + +++ D N DG+ Sbjct: 8 ELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRD-------IEEIIRDVDLNGDGR 60 Query: 162 LELTEMARLLPV 173 ++ E R++ Sbjct: 61 VDFEEFVRMMSR 72 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 30/77 (38%), Gaps = 5/77 (6%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 + +I + + + FD +G G + EL+ +++L +++ + Sbjct: 1 ADMIGVKELRDAFREFDTNGDGEISTSELREAMRKL-----LGHQVGHRDIEEIIRDVDL 55 Query: 68 RDDGKIGIVELAHVLPT 84 DG++ E ++ Sbjct: 56 NGDGRVDFEEFVRMMSR 72 Score = 35.2 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 3/56 (5%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 KE AF +D +G+G I +EL ++ L DI I +++ DG Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEI---IRDVDLNGDG 59 Score = 31.3 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 31/73 (42%), Gaps = 7/73 (9%) Query: 144 AEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGN 203 + + FD+N DG++ +E+ + K G ++ ++ + D +G+ Sbjct: 6 VKELRDAFREFDTNGDGEISTSELREAMR-------KLLGHQVGHRDIEEIIRDVDLNGD 58 Query: 204 GYIDENELDALLK 216 G +D E ++ Sbjct: 59 GRVDFEEFVRMMS 71 >1M39-A nrPDB Length = 89 Score = 56.4 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 38/91 (41%), Gaps = 8/91 (8%) Query: 87 NFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY 146 ++ + + + EE +K ++ +D D +G I + LK K+L E E Sbjct: 7 LTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD--------EE 58 Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 M+ D + DG++ E R++ + Sbjct: 59 LQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 89 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 34/81 (41%), Gaps = 6/81 (7%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 S T + + + FD D +G + K L+ + +EL + E++ +D+ + Sbjct: 15 SEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD------EELQEMIDEADR 68 Query: 68 RDDGKIGIVELAHVLPTEENF 88 DG++ E ++ + Sbjct: 69 DGDGEVSEQEFLRIMKKTSLY 89 Score = 28.6 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 8/90 (8%) Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKM 186 D L + + + E KLFD + GK+ + R+ K G + Sbjct: 3 FGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRV--------AKELGENL 54 Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLK 216 +E + + D+DG+G + E E ++K Sbjct: 55 TDEELQEMIDEADRDGDGEVSEQEFLRIMK 84 Score = 28.3 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 25/59 (42%), Gaps = 7/59 (11%) Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + + ++ + + K +E KAF+L+D D G I L + K+L E Sbjct: 1 MNFGDFLTVMTQKMS-------EKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGE 52 >5CPV-A nrPDB Length = 109 Score = 56.4 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 KS ++ K + D D SGFIE +ELK FL++ A D T LK DS Sbjct: 38 SKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGE-----TKTFLKAGDS 92 Query: 157 NNDGKLELTEMARLLPV 173 + DGK+ + E L+ Sbjct: 93 DGDGKIGVDEFTALVKA 109 Score = 39.4 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 3/72 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 +A + + D D SG++E EL+ +Q + A E KTF+ DG Sbjct: 40 SADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKAD---ARALTDGETKTFLKAGDSDGDG 96 Query: 72 KIGIVELAHVLP 83 KIG+ E ++ Sbjct: 97 KIGVDEFTALVK 108 Score = 32.1 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 1/68 (1%) Query: 177 FLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKK 236 F K + KAF + DQD +G+I+E+EL L++ + D T+ K Sbjct: 30 FFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTD-GETKTFLK 88 Query: 237 NIMALSDG 244 + DG Sbjct: 89 AGDSDGDG 96 >1F55-A nrPDB Length = 77 Score = 56.0 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 32/73 (43%), Gaps = 6/73 (8%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 ++F E + FD D +G + EL +++ L + +A E+ +++ + + Sbjct: 9 IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA------EVNDLMNEIDVDGNHQ 62 Query: 73 IGIVELAHVLPTE 85 I E ++ + Sbjct: 63 IEFSEFLALMSRQ 75 Score = 55.2 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 33/73 (45%), Gaps = 8/73 (10%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 EF + + +D D++G I + EL ++ L ++ + ++ D + + + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEA--------EVNDLMNEIDVDGNHQ 62 Query: 162 LELTEMARLLPVQ 174 +E +E L+ Q Sbjct: 63 IEFSEFLALMSRQ 75 Score = 37.1 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNI 231 EF +AF L+D+D NG I +EL +++ L + + ++N++ Sbjct: 10 AEFKEAFALFDKDNNGSISSSELATVMRSLG-LSPSEAEVNDL 51 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Query: 135 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKA 194 + + + ++AE+ + LFD +N+G + +E+A ++ + G+ E N Sbjct: 1 SSNLTEEQIAEFKEA-FALFDKDNNGSISSSELATVM--------RSLGLSPSEAEVNDL 51 Query: 195 FELYDQDGNGYIDENELDALLK 216 D DGN I+ +E AL+ Sbjct: 52 MNEIDVDGNHQIEFSEFLALMS 73 >4PAL-A nrPDB Length = 108 Score = 55.6 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 5/78 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 KS ++ K + D D SGFIE +ELK FL++ A D T L D Sbjct: 36 ASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAE-----TKAFLADGD 90 Query: 156 SNNDGKLELTEMARLLPV 173 + DG + + E A ++ Sbjct: 91 KDGDGMIGVDEFAAMIKA 108 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 3/72 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + + D D SG++E EL+ +Q + A E K F+ + DG Sbjct: 39 SLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPS---ARALTDAETKAFLADGDKDGDG 95 Query: 72 KIGIVELAHVLP 83 IG+ E A ++ Sbjct: 96 MIGVDEFAAMIK 107 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 177 FLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKK 236 F K + KAF + DQD +G+I+E+EL L++ + D + Sbjct: 29 FFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDA-ETKAFLA 87 Query: 237 NIMALSDG 244 + DG Sbjct: 88 DGDKDGDG 95 >1ZMZ-A nrPDB Length = 98 Score = 55.6 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 6/73 (8%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FDADG+G ++ KEL+ ++ L KK E+K + + + GK+ Sbjct: 31 QEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK------EEIKKMISEIDKEGTGKM 84 Query: 74 GIVELAHVLPTEE 86 + V+ + Sbjct: 85 NFGDFLTVMTQKM 97 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 33/79 (41%), Gaps = 8/79 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +D D +G I+ +ELK ++ L + K E M+ D Sbjct: 28 EQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKK--------EEIKKMISEIDKE 79 Query: 158 NDGKLELTEMARLLPVQEN 176 GK+ + ++ + + Sbjct: 80 GTGKMNFGDFLTVMTQKMS 98 Score = 35.2 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Query: 172 PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNI 231 ++ K + + +E +AF+L+D DG G ID EL ++ L + K++ I Sbjct: 14 SQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKE----EI 69 Query: 232 TTYKKNIMALSDG 244 I G Sbjct: 70 KKMISEIDKEGTG 82 Score = 27.9 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 30/76 (39%), Gaps = 8/76 (10%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 + + LFD++ G +++ E+ + + G + +E K D+ Sbjct: 27 EEQKQEIREAFDLFDADGTGTIDVKELKVAM--------RALGFEPKKEEIKKMISEIDK 78 Query: 201 DGNGYIDENELDALLK 216 +G G ++ + ++ Sbjct: 79 EGTGKMNFGDFLTVMT 94 Score = 27.9 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 24/80 (30%), Gaps = 9/80 (11%) Query: 49 KAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWR 108 + E E++ D + G I + EL + EE K Sbjct: 24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAM---------RALGFEPKKEEIKKMIS 74 Query: 109 KYDTDHSGFIETEELKNFLK 128 + D + +G + + + Sbjct: 75 EIDKEGTGKMNFGDFLTVMT 94 >1A75-A nrPDB Length = 108 Score = 54.8 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 5/78 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 KS ++ K + D D SGFIE +ELK FL+ A D T LK D Sbjct: 36 SGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAE-----TKAFLKAGD 90 Query: 156 SNNDGKLELTEMARLLPV 173 S+ DG + + E L+ Sbjct: 91 SDGDGAIGVEEWVALVKA 108 Score = 40.6 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 3/72 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 +A + ++ D D SG++E EL+ +Q + A E K F+ DG Sbjct: 39 SADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAG---ARALTDAETKAFLKAGDSDGDG 95 Query: 72 KIGIVELAHVLP 83 IG+ E ++ Sbjct: 96 AIGVEEWVALVK 107 Score = 27.9 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 1/69 (1%) Query: 177 FLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKK 236 F K + KAF DQD +G+I+E+EL L+ + D + K Sbjct: 29 FFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDA-ETKAFLK 87 Query: 237 NIMALSDGG 245 + DG Sbjct: 88 AGDSDGDGA 96 >1Y1X-A nrPDB Length = 191 Score = 54.5 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 48/125 (38%), Gaps = 22/125 (17%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 +E M+ +R DTD SG I EL L + T+ +L ++D N+ G Sbjct: 27 QELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLAT--------TEKLLHMYDKNHSG 78 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 ++ E +F+L + F D G+G +D NE+ A L Sbjct: 79 EITFDEF----KDLHHFILS----------MREGFRKRDSSGDGRLDSNEVRAALLSSGY 124 Query: 221 KNKQD 225 + + Sbjct: 125 QVSEQ 129 Score = 54.5 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 31/198 (15%), Positives = 60/198 (30%), Gaps = 43/198 (21%) Query: 10 LITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 + + E + D DGSG + EL + A + + Y + Sbjct: 23 MNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLA------TTEKLLHMYDKNH 76 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 G+I E +F+L R + +RK D+ G +++ E++ L Sbjct: 77 SGEITFDEF----KDLHHFILSMR-----------EGFRKRDSSGDGRLDSNEVRAALLS 121 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGK 189 + ++ +++ FD G L + L Sbjct: 122 SGYQVSEQTFQ--------ALMRKFDRQRRGSLGFDDYVELSIFVCR------------- 160 Query: 190 EFNKAFELYDQDGNGYID 207 F YD++ G + Sbjct: 161 -VRNVFAFYDRERTGQVT 177 >3DTP-E nrPDB Length = 196 Score = 54.5 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 24/161 (14%), Positives = 53/161 (32%), Gaps = 27/161 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 +F E + D D G++ +++ L + + E+ + V + G Sbjct: 56 VQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTE------QELDSMVAEA----PGP 105 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I + R + + + +D + G + E LK L E Sbjct: 106 INFTMFLTIFGD--------RIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTWGE 156 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 K + + D L + +G +++ + A++L Sbjct: 157 KFS--------QDEVDQALSEAPIDGNGLIDIKKFAQILTK 189 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 42/125 (33%), Gaps = 20/125 (16%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 +EF + ++ D D GFI +++ L + D+ +AE G Sbjct: 57 QEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVAEAP------------G 104 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + T + + AF L+D +G+G E L L E Sbjct: 105 PINFTMFLTIFGDRIAGT-------DEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTWGE 156 Query: 221 KNKQD 225 K QD Sbjct: 157 KFSQD 161 >1QXP-A nrPDB Length = 900 Score = 54.1 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 69/206 (33%), Gaps = 42/206 (20%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQEL--QQARKKAGLELSPEMKT 60 E L I F ++ D + KELQ ++ + + + ++ Sbjct: 524 EKVLSEEEID-DNFKTLFSKLAGD-DMEISVKELQTILNRIISKHKDLRTNGFSLESCRS 581 Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 V+ + +GK+G+VE + N+L + +RK+D D SG + Sbjct: 582 MVNLMDRDGNGKLGLVEFNILWNRIRNYLTI---------------FRKFDLDKSGSMSA 626 Query: 121 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 180 E++ ++ K + +A + D L ++ R L Sbjct: 627 YEMRMAIEAAGFKLPCQLHQVIVARFADDEL---------IIDFDNFVRCL--------- 668 Query: 181 FQGIKMCGKEFNKAFELYDQDGNGYI 206 + + K F+ D + G I Sbjct: 669 -----VRLEILFKIFKQLDPENTGTI 689 Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 48/142 (33%), Gaps = 17/142 (11%) Query: 99 SCEEFMKTWR-KYDT--DHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 S EE ++ + I +EL+ L ++ K + E M+ L D Sbjct: 528 SEEEIDDNFKTLFSKLAGDDMEISVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMD 587 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 + +GKL L E L N+L F +D D +G + E+ + Sbjct: 588 RDGNGKLGLVEFNILWNRIRNYLT--------------IFRKFDLDKSGSMSAYEMRMAI 633 Query: 216 KDLCEKNKQDLDINNITTYKKN 237 + K L + + + Sbjct: 634 EAAGFKLPCQLHQVIVARFADD 655 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 41/248 (16%), Positives = 76/248 (30%), Gaps = 66/248 (26%) Query: 16 FFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGI 75 + I+ FD D SG + E++ I+ AG +L ++ + D+ I Sbjct: 609 YLTIFRKFDLDKSGSMSAYEMRMAIEA-------AGFKLPCQLHQVIVARFADDELIIDF 661 Query: 76 VELAHVLPTEENFLLLFR------------------------------------------ 93 L E +F+ Sbjct: 662 DNFVRCLVRLEILFKIFKQLDPENTGTIQLDLISWLSFSVLGKLAAAIEHHHHHHMHYSN 721 Query: 94 CQQLKSCEE--FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 151 + +S EE F K + + D + EL N L ++ + D + M+ Sbjct: 722 IEANESEEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMV 780 Query: 152 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 + DS+ GKL E + + K++ ++ ++ D +G I NEL Sbjct: 781 AVMDSDTTGKLGFEEF--------------KYLWNNIKKWQGIYKRFETDRSGTIGSNEL 826 Query: 212 DALLKDLC 219 + Sbjct: 827 PGAFEAAG 834 Score = 33.3 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 32/100 (32%), Gaps = 22/100 (22%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 I+ F+ D SG + EL + AG L+ + + + + + G + Sbjct: 809 IYKRFETDRSGTIGSNELPGAFEA-------AGFHLNQHIYSMIIRRYSDETGNMDFDNF 861 Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 L + + +R D + +G I Sbjct: 862 ISCLVRL---------------DAMFRAFRSLDKNGTGQI 886 >2N7L-C nrPDB Length = 141 Score = 54.1 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 26/73 (35%), Gaps = 7/73 (9%) Query: 15 QFFEIWLHFD-ADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 +F + F G + KEL +++ L Q E++ +D+ + G + Sbjct: 34 EFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPT------PEELQEMIDEVDEDGSGTV 87 Query: 74 GIVELAHVLPTEE 86 E ++ Sbjct: 88 DFDEFLVMMVRXM 100 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 102 EFMKTWRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EF + + G I T+EL ++ L + E M+ D + G Sbjct: 34 EFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPT--------PEELQEMIDEVDEDGSG 85 Query: 161 KLELTEMARLL 171 ++ E ++ Sbjct: 86 TVDFDEFLVMM 96 >1I84-U nrPDB Length = 166 Score = 54.1 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 51/159 (32%), Gaps = 18/159 (11%) Query: 85 EENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLA 144 E +F E+F + + D + G I+ ++L+ + K Sbjct: 9 AEGSSNVFSMFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN------- 61 Query: 145 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 E D M+K G + T + + AF++ D DG G Sbjct: 62 EELDAMIKEA----SGPINFTVFLTMFGEKLKG-------ADPEDVIMGAFKVLDPDGKG 110 Query: 205 YIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 I ++ L+ LL + + N + ++ D Sbjct: 111 SIKKSFLEELLTTGGGRFTPEEIKNMWAAFPPDVAGNVD 149 Score = 46.7 bits (109), Expect = 9e-06, Method: Composition-based stats. Identities = 20/161 (12%), Positives = 47/161 (29%), Gaps = 25/161 (15%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 F E + D + G ++ +L+ + + K + E+ + + G Sbjct: 23 EIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVK-----NEELDAMIKEA----SG 73 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I + + + + M ++ D D G I+ L+ L Sbjct: 74 PINFTVFLTMFGE--------KLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGG 125 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 + E M F + G ++ + ++ Sbjct: 126 GRFT--------PEEIKNMWAAFPPDVAGNVDYKNICYVIT 158 >2KYF-A nrPDB Length = 108 Score = 54.1 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 5/76 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 KS + + +R D D SGFIE +ELK FL+ A A T L D Sbjct: 36 SKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLT-----ASETKTFLAAAD 90 Query: 156 SNNDGKLELTEMARLL 171 + DGK+ E ++ Sbjct: 91 HDGDGKIGAEEFQEMV 106 Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQR 68 S ++SQ EI+ D D SG++E EL+ +Q + A + + E KTF+ Sbjct: 36 SKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESG---ARVLTASETKTFLAAADHD 92 Query: 69 DDGKIGIVELAHVL 82 DGKIG E ++ Sbjct: 93 GDGKIGAEEFQEMV 106 Score = 29.4 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 182 QGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMAL 241 K + + F + D D +G+I+E+EL L+ E + L + T+ Sbjct: 34 GMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRF-ESGARVLTASETKTFLAAADHD 92 Query: 242 SDG 244 DG Sbjct: 93 GDG 95 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 28/76 (36%), Gaps = 5/76 (6%) Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 K + + ++ D++ G +E E+ L E+ + E D D Sbjct: 38 KSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESG-----ARVLTASETKTFLAAADHD 92 Query: 202 GNGYIDENELDALLKD 217 G+G I E +++ Sbjct: 93 GDGKIGAEEFQEMVQS 108 Score = 29.0 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 26/77 (33%), Gaps = 6/77 (7%) Query: 53 ELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDT 112 + S ++K G I EL + L E+ + + K+ D Sbjct: 38 KSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKT------FLAAADH 91 Query: 113 DHSGFIETEELKNFLKD 129 D G I EE + ++ Sbjct: 92 DGDGKIGAEEFQEMVQS 108 >1S1E-A nrPDB Length = 224 Score = 54.1 bits (128), Expect = 7e-08, Method: Composition-based stats. Identities = 26/174 (14%), Positives = 58/174 (33%), Gaps = 24/174 (13%) Query: 80 HVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTV 138 ++ L Q + E +R + + SG + E K Sbjct: 30 TMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHG---- 85 Query: 139 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELY 198 + Y + FD+ G ++ + L + + ++ F LY Sbjct: 86 ---DASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVH--------EKLRWTFNLY 134 Query: 199 DQDGNGYIDENELDALLKDLCEKN--------KQDLDINNITTYKKNIMALSDG 244 D + +GYI++ E+ ++K + + K+D ++ + + + DG Sbjct: 135 DINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDG 188 Score = 47.9 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 41/120 (34%), Gaps = 13/120 (10%) Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 + + G + + L + E+ T+ YD + G+I Sbjct: 94 LFNAFDTTQTGSVKFEDFVTALS---------ILLRGTVHEKLRWTFNLYDINKDGYINK 144 Query: 121 EELKNFLKD----LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 EE+ + +K + + + + ++ D+ + D N DG + L E +N Sbjct: 145 EEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 204 >1BU3-A nrPDB Length = 109 Score = 53.7 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 KS ++ K + D D SGFIE +ELK FL+ A D T LK DS Sbjct: 38 AKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAE-----TKAFLKAGDS 92 Query: 157 NNDGKLELTEMARLLPV 173 + DG + + E A L+ Sbjct: 93 DGDGAIGVDEWAALVKA 109 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 +A + + D D SG++E EL+ +Q A E K F+ DG Sbjct: 40 SADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAG---ARALTDAETKAFLKAGDSDGDG 96 Query: 72 KIGIVELAHVLP 83 IG+ E A ++ Sbjct: 97 AIGVDEWAALVK 108 Score = 29.4 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 177 FLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKK 236 F K + KAF + DQD +G+I+E+EL L+ + D + K Sbjct: 30 FFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDA-ETKAFLK 88 Query: 237 NIMALSDGG 245 + DG Sbjct: 89 AGDSDGDGA 97 >5ZGM-A nrPDB Length = 110 Score = 53.7 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + KS + + + D D SGFIE EELK+ LK D T +L D Sbjct: 37 KGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTE-----TKALLAAGD 91 Query: 156 SNNDGKLELTEMARLLP 172 S++DGK+ E A+++ Sbjct: 92 SDHDGKIGADEFAKMVA 108 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + +Q E++ D D SG++E +EL+++++ + E K + DG Sbjct: 40 SEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLS---DTETKALLAAGDSDHDG 96 Query: 72 KIGIVELAHVLPTE 85 KIG E A ++ Sbjct: 97 KIGADEFAKMVAQA 110 Score = 30.6 bits (67), Expect = 0.65, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 27/57 (47%), Gaps = 10/57 (17%) Query: 160 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 G + +L+ ++ + + FE+ D+D +G+I+E EL ++LK Sbjct: 23 GTFDYKRFFQLVGLKGK----------SEAQVKEVFEILDKDQSGFIEEEELKSVLK 69 >2KQY-A nrPDB Length = 108 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 5/78 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 K+ ++ K + D D SGFIE EEL+ FLK+ A T L D Sbjct: 36 SSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAE-----TKAFLAAGD 90 Query: 156 SNNDGKLELTEMARLLPV 173 ++ DGK+ + E L+ Sbjct: 91 TDGDGKIGVEEFQSLVKA 108 Score = 43.7 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 3/69 (4%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 Q +++ D D SG++E +ELQ ++ + A + S E K F+ DGKIG Sbjct: 42 QIKKVFGILDQDKSGFIEEEELQLFLKNFSSS---ARVLTSAETKAFLAAGDTDGDGKIG 98 Query: 75 IVELAHVLP 83 + E ++ Sbjct: 99 VEEFQSLVK 107 Score = 27.9 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 21/48 (43%) Query: 176 NFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNK 223 +F + K F + DQD +G+I+E EL LK+ + Sbjct: 28 SFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSAR 75 Score = 26.7 bits (57), Expect = 9.1, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 26/77 (33%), Gaps = 6/77 (7%) Query: 53 ELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDT 112 + ++K Q G I EL L + + + K+ DT Sbjct: 38 KTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKA------FLAAGDT 91 Query: 113 DHSGFIETEELKNFLKD 129 D G I EE ++ +K Sbjct: 92 DGDGKIGVEEFQSLVKA 108 >2K2I-A nrPDB Length = 79 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 8/85 (9%) Query: 93 RCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLK 152 + + + EE +K ++ +D D +G I + LK K+L E E M+ Sbjct: 3 KMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD--------EELQEMID 54 Query: 153 LFDSNNDGKLELTEMARLLPVQENF 177 D + DG++ E R++ + Sbjct: 55 EADRDGDGEVSEQEFLRIMKKTSLY 79 Score = 37.1 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 34/81 (41%), Gaps = 6/81 (7%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 S T + + + FD D +G + K L+ + +EL + E++ +D+ + Sbjct: 5 SEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD------EELQEMIDEADR 58 Query: 68 RDDGKIGIVELAHVLPTEENF 88 DG++ E ++ + Sbjct: 59 DGDGEVSEQEFLRIMKKTSLY 79 Score = 27.1 bits (58), Expect = 7.2, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 34/82 (41%), Gaps = 8/82 (9%) Query: 135 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKA 194 + + + E KLFD + GK+ + R+ K G + +E + Sbjct: 1 TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRV--------AKELGENLTDEELQEM 52 Query: 195 FELYDQDGNGYIDENELDALLK 216 + D+DG+G + E E ++K Sbjct: 53 IDEADRDGDGEVSEQEFLRIMK 74 >5VLN-A nrPDB Length = 120 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 26/73 (35%), Gaps = 7/73 (9%) Query: 15 QFFEIWLHFD-ADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 +F + F G + KEL +++ L Q E++ +D+ + G + Sbjct: 19 EFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPT------PEELQEMIDEVDEDGSGTV 72 Query: 74 GIVELAHVLPTEE 86 E ++ Sbjct: 73 DFDEFLVMMVRSM 85 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 29/92 (31%), Gaps = 9/92 (9%) Query: 102 EFMKTWRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EF + + G I T+EL ++ L + E M+ D + G Sbjct: 19 EFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPT--------PEELQEMIDEVDEDGSG 70 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 ++ E ++ K + + + Sbjct: 71 TVDFDEFLVMMVRSMKDDSKGKFKRPTLRRVR 102 >1S6C-A nrPDB Length = 183 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 24/155 (15%), Positives = 54/155 (34%), Gaps = 24/155 (15%) Query: 99 SCEEFMKTWRKYDTD-HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + E +R + + SG + E K + Y + FD+ Sbjct: 16 TKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHG-------DASTYAHYLFNAFDTT 68 Query: 158 NDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 G ++ + L + + ++ F LYD + +GYI++ E+ ++K Sbjct: 69 QTGSVKFEDFVTALSILLRGTVH--------EKLRWTFNLYDINKDGYINKEEMMDIVKA 120 Query: 218 LCEKN--------KQDLDINNITTYKKNIMALSDG 244 + + K+D ++ + + + DG Sbjct: 121 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDG 155 Score = 48.3 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 41/120 (34%), Gaps = 13/120 (10%) Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 + + G + + L + E+ T+ YD + G+I Sbjct: 61 LFNAFDTTQTGSVKFEDFVTALS---------ILLRGTVHEKLRWTFNLYDINKDGYINK 111 Query: 121 EELKNFLKD----LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 EE+ + +K + + + + ++ D+ + D N DG + L E +N Sbjct: 112 EEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 171 >5TBY-E nrPDB Length = 166 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 22/164 (13%), Positives = 55/164 (33%), Gaps = 25/164 (15%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQR 68 +F E + D + G+++ +L++ L + K +D+ + Sbjct: 22 EQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEE---------IDEMIKE 72 Query: 69 DDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLK 128 G I + + + E + ++ +D + G ++ + ++ L Sbjct: 73 APGPINFTVFLTMFGE--------KLKGADPEETILNAFKVFDPEGKGVLKADYVREMLT 124 Query: 129 DLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 E+ +K E D M F + G L+ + ++ Sbjct: 125 TQAERFSK--------EEVDQMFAAFPPDVTGNLDYKNLVHIIT 160 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 53/138 (38%), Gaps = 19/138 (13%) Query: 91 LFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLM 150 +F + +EF + + D + GFI+ +L++ L K E D M Sbjct: 17 VFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKN-------EEIDEM 69 Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 +K G + T + + + AF+++D +G G + + Sbjct: 70 IKEA----PGPINFTVFLTMFGEKLKG-------ADPEETILNAFKVFDPEGKGVLKADY 118 Query: 211 LDALLKDLCEK-NKQDLD 227 + +L E+ +K+++D Sbjct: 119 VREMLTTQAERFSKEEVD 136 Score = 34.0 bits (76), Expect = 0.073, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 27/45 (60%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITT 233 +EF +AF + DQ+ +G+ID+N+L L N ++ +I+ + Sbjct: 27 QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIK 71 >1TTX-A nrPDB Length = 109 Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQR 68 S ++A+Q +++ D D SGYL+ +EL+ +Q+ + ++ E K+ + Sbjct: 37 SKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTE---SETKSLMAAADND 93 Query: 69 DDGKIGIVELAHVL 82 DGKIG E ++ Sbjct: 94 GDGKIGAEEFQEMV 107 Score = 47.5 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S + +R D D SG+++ EELK FL+ A + + T ++ D++ Sbjct: 40 SANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESE-----TKSLMAAADNDG 94 Query: 159 DGKLELTEMARLL 171 DGK+ E ++ Sbjct: 95 DGKIGAEEFQEMV 107 Score = 27.5 bits (59), Expect = 5.6, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 5/72 (6%) Query: 144 AEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGN 203 A + + D++ G L+ E+ L E+ + + E D DG+ Sbjct: 41 ANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARE-----LTESETKSLMAAADNDGD 95 Query: 204 GYIDENELDALL 215 G I E ++ Sbjct: 96 GKIGAEEFQEMV 107 >3E3R-A nrPDB Length = 204 Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 24/157 (15%), Positives = 54/157 (34%), Gaps = 27/157 (17%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 + +R+ D D S ++ +E + L L + + + + +D N G L Sbjct: 39 LARFFRQLDRDGSRSLDADEFRQGLAKLGLVLD--------QAEAEGVCRKWDRNGSGTL 90 Query: 163 ELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK------ 216 +L E R L+ + AF D+ G+G + ++L + Sbjct: 91 DLEEFLRA--------LRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPK 142 Query: 217 -DLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDL 252 E + ++ + + N + G++ + Sbjct: 143 VRSGEWTEDEV----LRRFLDNFDSSEKDGQVTLAEF 175 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 25/156 (16%), Positives = 45/156 (28%), Gaps = 17/156 (10%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + D DGS L+ E + + +L +A E + ++ + G Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQA------EAEGVCRKWDRNGSGT 89 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + E L + K D G + ++L+ Sbjct: 90 LDLEEFLRALRPPM---------SQAREAVIAAAFAKLDRSGDGVVTVDDLRGVY-SGRA 139 Query: 133 KANKTVDDTKLAEYTDLMLKLFD-SNNDGKLELTEM 167 + E L FD S DG++ L E Sbjct: 140 HPKVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLAEF 175 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 26/172 (15%), Positives = 59/172 (34%), Gaps = 19/172 (11%) Query: 40 IQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKS 99 +++L+ G + F Q + + E L L Sbjct: 21 MEKLRAQCLSRGASGIQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVL---------D 71 Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 E RK+D + SG ++ EE L+ + +A + V A+ D + D Sbjct: 72 QAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKL--------DRSGD 123 Query: 160 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD-QDGNGYIDENE 210 G + + ++ + + + ++ G + + + +D + +G + E Sbjct: 124 GVVTVDDLRGVYSGRAHPKVR-SGEWTEDEVLRRFLDNFDSSEKDGQVTLAE 174 >4GJF-A nrPDB Length = 89 Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 26/71 (36%), Gaps = 7/71 (9%) Query: 15 QFFEIWLHF-DADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 +F + F G + KEL +++ L Q E++ +D+ + G + Sbjct: 19 EFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPT------PEELQEMIDEVDEDGSGTV 72 Query: 74 GIVELAHVLPT 84 E ++ Sbjct: 73 DFDEFLVMMVR 83 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 25/71 (35%), Gaps = 9/71 (12%) Query: 102 EFMKTWRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EF + + G I T+EL ++ L + E M+ D + G Sbjct: 19 EFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPT--------PEELQEMIDEVDEDGSG 70 Query: 161 KLELTEMARLL 171 ++ E ++ Sbjct: 71 TVDFDEFLVMM 81 >2M97-A nrPDB Length = 69 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 36/73 (49%), Gaps = 8/73 (10%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S EE + +R +D D +GFI+ EE + ++ E+ E D + D++ Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTD--------EDVDEIFGDSDTDK 52 Query: 159 DGKLELTEMARLL 171 +G+++ E +++ Sbjct: 53 NGRIDFDEFLKMM 65 Score = 36.0 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 29/72 (40%), Gaps = 6/72 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + E + FD DG+G+++ +E ++I+ + ++ +G+I Sbjct: 4 ELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTD------EDVDEIFGDSDTDKNGRID 57 Query: 75 IVELAHVLPTEE 86 E ++ + Sbjct: 58 FDEFLKMMENVQ 69 Score = 33.6 bits (75), Expect = 0.076, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 35/74 (47%), Gaps = 8/74 (10%) Query: 145 EYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 E ++FD + +G ++ E ++ + G ++ ++ ++ F D D NG Sbjct: 3 EELSECFRIFDKDGNGFIDREEFGDIIRLT--------GEQLTDEDVDEIFGDSDTDKNG 54 Query: 205 YIDENELDALLKDL 218 ID +E +++++ Sbjct: 55 RIDFDEFLKMMENV 68 Score = 31.0 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 22/35 (62%) Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 +E ++ F ++D+DGNG+ID E +++ E+ Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQ 35 >1O1A-B nrPDB Length = 145 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 48/143 (33%), Gaps = 18/143 (12%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E+F + + D + G I+ ++L+ + K E D M+K G Sbjct: 7 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN-------EELDAMIKEA----SG 55 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + T + + AF++ D DG G I ++ L+ LL Sbjct: 56 PINFTVFLTMFGEKLKG-------ADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGG 108 Query: 221 KNKQDLDINNITTYKKNIMALSD 243 + + N + ++ D Sbjct: 109 RFTPEEIKNMWAAFPPDVAGNVD 131 Score = 46.7 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 20/161 (12%), Positives = 47/161 (29%), Gaps = 25/161 (15%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 F E + D + G ++ +L+ + + K + E+ + + G Sbjct: 5 EIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVK-----NEELDAMIKEA----SG 55 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 I + + + + M ++ D D G I+ L+ L Sbjct: 56 PINFTVFLTMFGE--------KLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGG 107 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 + E M F + G ++ + ++ Sbjct: 108 GRFT--------PEEIKNMWAAFPPDVAGNVDYKNICYVIT 140 >2MBX-A nrPDB Length = 109 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 KS + K + D D S F+E +ELK FL++ A D T + LK D Sbjct: 37 AAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAE-----TKVFLKAGD 91 Query: 156 SNNDGKLELTEMARLLPV 173 S+ DGK+ + E ++ Sbjct: 92 SDGDGKIGVDEFGAMIKA 109 Score = 37.5 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + +++ D D S ++E EL+ +Q + E K F+ DG Sbjct: 40 SPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALS---DAETKVFLKAGDSDGDG 96 Query: 72 KIGIVELAHVLP 83 KIG+ E ++ Sbjct: 97 KIGVDEFGAMIK 108 >2E30-A nrPDB Length = 195 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 24/163 (14%), Positives = 54/163 (33%), Gaps = 20/163 (12%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELA 79 + D +G L ++ Q + L ++P ++ + + ++ Sbjct: 35 FTSLDKGENGTLSREDFQ----------RIPELAINPLGDRIINAFFPEGEDQVNFRGFM 84 Query: 80 HVLPTEENFLLLFRCQQLKSCE-------EFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 L + + + E + +R YD D I +EL L+ + Sbjct: 85 RTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDELLQVLRMM-- 142 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQE 175 + D +L D ++ D + D + TE ++L + Sbjct: 143 -VGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVD 184 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 21/150 (14%), Positives = 47/150 (31%), Gaps = 21/150 (14%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 + D +G + E+ + + + D ++ F + ++ Sbjct: 31 LYSRFTSLDKGENGTLSREDFQRI------------PELAINPLGDRIINAFFPEGEDQV 78 Query: 163 ELTEMARLLP--------VQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 R L + + + + + + AF LYD D + I +EL + Sbjct: 79 NFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEKISRDELLQV 138 Query: 215 LKDLCEKNKQDLDINNI-TTYKKNIMALSD 243 L+ + N D + +I + D Sbjct: 139 LRMMVGVNISDEQLGSIADRTIQEADQDGD 168 Score = 36.7 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 24/73 (32%), Gaps = 1/73 (1%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 + +D D + EL +++ + + +L + + Q D I E Sbjct: 118 AFRLYDLDKDEKISRDELLQVLRMM-VGVNISDEQLGSIADRTIQEADQDGDSAISFTEF 176 Query: 79 AHVLPTEENFLLL 91 VL + + Sbjct: 177 VKVLEKVDVEQKM 189 >1V1G-A nrPDB Length = 222 Score = 52.1 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 52/140 (37%), Gaps = 10/140 (7%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 D + + +G I E L + E+ ++ YD +GFI Sbjct: 77 DRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPV--------HEKVKFAFKLYDLRQTGFI 128 Query: 119 ETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 E EELK + LL ++ + + + D D NDGK+++ E + + N Sbjct: 129 EREELKEMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSL--NPS 186 Query: 179 LKFQGIKMCGKEFNKAFELY 198 L K+ N+ F + Sbjct: 187 LIKNMTLPYLKDINRTFPSF 206 Score = 47.9 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 55/155 (35%), Gaps = 24/155 (15%) Query: 101 EEFMKTWRKYDTDH-----SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 EE + + G I EE + L + + + D + +FD Sbjct: 34 EEVEALYELFKKLSSSIIDDGLIHKEEFQLALFR---------NRNRRNLFADRIFDVFD 84 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 +G +E E R L V F ++ AF+LYD G+I+ EL ++ Sbjct: 85 VKRNGVIEFGEFVRSLGV-------FHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMV 137 Query: 216 KDLCEKNKQDLDINNITTYKKNIMALSD---GGKL 247 L +++ L + I +D GK+ Sbjct: 138 VALLHESELVLSEDMIEVMVDKAFVQADRKNDGKI 172 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 32/186 (17%), Positives = 66/186 (35%), Gaps = 8/186 (4%) Query: 31 LEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLL 90 + K+ +N ++ + ++P V+ + + ++ EE L Sbjct: 5 VSKKKKKNAMRPPGYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLA 64 Query: 91 LFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLM 150 LFR + ++ + + +D +G I E F++ L + E Sbjct: 65 LFRNRNRRNLFA-DRIFDVFDVKRNGVI---EFGEFVRSLGVFH----PSAPVHEKVKFA 116 Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 KL+D G +E E+ ++ + M +KAF D+ +G ID +E Sbjct: 117 FKLYDLRQTGFIEREELKEMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDE 176 Query: 211 LDALLK 216 + Sbjct: 177 WKDFVS 182 Score = 31.7 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 35/74 (47%), Gaps = 8/74 (10%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV-----DQYGQRD 69 + + +D +G++E +EL+ ++ L ++ L LS +M + Q +++ Sbjct: 112 KVKFAFKLYDLRQTGFIEREELKEMVVAL---LHESELVLSEDMIEVMVDKAFVQADRKN 168 Query: 70 DGKIGIVELAHVLP 83 DGKI I E + Sbjct: 169 DGKIDIDEWKDFVS 182 >2JNX-A nrPDB Length = 134 Score = 52.1 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 50/152 (32%), Gaps = 24/152 (15%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE 77 ++ DA+G G + +E++ + K ++ ++ +G+I + E Sbjct: 4 ALFKQLDANGDGSVSYEEVKAFVSS------KRPIKNEQLLQLIFKAIDIDGNGEIDLAE 57 Query: 78 LAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT 137 + L ++ D D G + EE+ F K Sbjct: 58 FTKFAAAVKEQDL------SDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFG------ 105 Query: 138 VDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + D ++K D+N DG + L E Sbjct: 106 -----YEKVVDQIMK-ADANGDGYITLEEFLA 131 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 45/113 (39%), Gaps = 13/113 (11%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 +++ D + G + EE+K F+ K + L+ K D + +G+++L E Sbjct: 6 FKQLDANGDGSVSYEEVKAFVSS--------KRPIKNEQLLQLIFKAIDIDGNGEIDLAE 57 Query: 167 MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 + +K Q + ++L D DG+G + + E+ K Sbjct: 58 FTKFAAA-----VKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFG 105 Score = 44.4 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 33/156 (21%), Positives = 57/156 (36%), Gaps = 26/156 (16%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 + Q DG + E+ + ++ + +K+ + ++ D D +G I Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSK---------RPIKNEQLLQLIFKAIDIDGNGEI 53 Query: 119 ETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 + E F A K D + ++ KL D++ DGKL E+ F Sbjct: 54 DLAEFTKF-----AAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVT-------TFF 101 Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 KF K+ + D +G+GYI E A Sbjct: 102 KKFGYEKVVDQIMKA-----DANGDGYITLEEFLAF 132 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 40/106 (37%), Gaps = 10/106 (9%) Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 + + K D+N DG + E+ + + + F+ D DGNG I Sbjct: 2 AEALFKQLDANGDGSVSYEEVKAFVSSKRPIK--------NEQLLQLIFKAIDIDGNGEI 53 Query: 207 DENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDL 252 D E + E++ D + YK +M GKL + ++ Sbjct: 54 DLAEFTKFAAAVKEQDLSDEKVGLKILYK--LMDADGDGKLTKEEV 97 Score = 29.8 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 22/67 (32%), Gaps = 10/67 (14%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 ++ DADG G L +E+ ++ ++ + + DG I Sbjct: 76 GLKILYKLMDADGDGKLTKEEVTTFFKKFG----------YEKVVDQIMKADANGDGYIT 125 Query: 75 IVELAHV 81 + E Sbjct: 126 LEEFLAF 132 >4OKH-A nrPDB Length = 189 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 48/126 (38%), Gaps = 15/126 (11%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 Q+ + ++F +++ D I +ELK L ++ K E M+ L Sbjct: 5 DQESEEQQQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIAL 63 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 D++ GKL L E + K + K F+ YD D +G I+ E+ Sbjct: 64 MDTDGSGKLNLQEF--------------HHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 109 Query: 214 LLKDLC 219 + D Sbjct: 110 AVNDAG 115 Score = 49.4 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 33/195 (16%), Positives = 64/195 (32%), Gaps = 41/195 (21%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQEL--QQARKKAGLELSPEMKTFVDQYGQRDDG 71 QF I+ D + EL+ ++ + + K ++ + G Sbjct: 12 QQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSG 70 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLL 131 K+ + E H+ + + K ++ YDTD SG I + E++N + D Sbjct: 71 KLNLQEFHHLWNKIKAW---------------QKIFKHYDTDQSGTINSYEMRNAVNDAG 115 Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEF 191 N + D Y D + ++ + + Sbjct: 116 FHLNNQLYDIITMRYADKHMN---------IDFDSFI--------------CCFVRLEGM 152 Query: 192 NKAFELYDQDGNGYI 206 +AF +D+DG+G I Sbjct: 153 FRAFHAFDKDGDGII 167 Score = 29.4 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 37/133 (27%), Gaps = 32/133 (24%) Query: 6 LQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQY 65 L++ T + D DGSG L +E +L +++ + Y Sbjct: 47 LKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKA------------WQKIFKHY 94 Query: 66 GQRDDGKIGIVELAHVLPTEENFLL-----LFRCQQLKSC---------------EEFMK 105 G I E+ + + L + + E + Sbjct: 95 DTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFR 154 Query: 106 TWRKYDTDHSGFI 118 + +D D G I Sbjct: 155 AFHAFDKDGDGII 167 >3DF0-A nrPDB Length = 714 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 31/194 (15%), Positives = 66/194 (34%), Gaps = 41/194 (21%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQEL--QQARKKAGLELSPEMKTFVDQYGQRDDGK 72 F ++ + + ELQ +++ + ++ K+ K VD + GK Sbjct: 533 GFRRLFAQLAGE-DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGK 591 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 +G+ E + + ++ K +R+ D D SG + + E++ L++ Sbjct: 592 LGLKEFYILWTKIQ---------------KYQKIYREIDVDRSGTMNSYEMRKALEEAGF 636 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 K + +A + D L ++ R L + + Sbjct: 637 KLPCQLHQVIVARFADDEL---------IIDFDNFVRCL--------------VRLEILF 673 Query: 193 KAFELYDQDGNGYI 206 K F+ D + G I Sbjct: 674 KIFKQLDPENTGTI 687 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 44/123 (35%), Gaps = 14/123 (11%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 I EL+ L+ +L K D E +M+ + D + GKL L E L Sbjct: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTK- 603 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTY 234 +++ K + D D +G ++ E+ L++ K L + + Sbjct: 604 -------------IQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARF 650 Query: 235 KKN 237 + Sbjct: 651 ADD 653 Score = 33.6 bits (75), Expect = 0.093, Method: Composition-based stats. Identities = 27/127 (21%), Positives = 52/127 (40%), Gaps = 8/127 (6%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKE---LQNLIQELQQ-----ARKKAGLEL 54 ++S + + D DGSG L KE L IQ+ Q+ ++G Sbjct: 564 REDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMN 623 Query: 55 SPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDH 114 S EM+ +++ G + ++ V +A E + L E K +++ D ++ Sbjct: 624 SYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFDNFVRCLVRLEILFKIFKQLDPEN 683 Query: 115 SGFIETE 121 +G I+ + Sbjct: 684 TGTIQLD 690 >1KFU-L nrPDB Length = 699 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 63/185 (34%), Gaps = 27/185 (14%) Query: 77 ELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 + V E L F + + + + + I EL+ L+ +L K Sbjct: 507 DYQAVDDEIEANLEEFDISEDDIDDGVRRLFAQL-AGEDAEISAFELQTILRRVLAKRQD 565 Query: 137 TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFE 196 D E +M+ + DS+ GKL L E L +++ K + Sbjct: 566 IKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTK--------------IQKYQKIYR 611 Query: 197 LYDQDGNGYIDENELDALLKDLCEKNKQDLD------------INNITTYKKNIMALSDG 244 D D +G ++ E+ L++ K L I + + + ++ L Sbjct: 612 EIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETL 671 Query: 245 GKLYR 249 K+++ Sbjct: 672 FKIFK 676 Score = 50.6 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 31/182 (17%), Positives = 61/182 (33%), Gaps = 40/182 (21%) Query: 28 SGYLEGKELQNLIQEL--QQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTE 85 + ELQ +++ + ++ K+ K VD GK+G+ E + Sbjct: 544 DAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKI 603 Query: 86 ENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE 145 + ++ K +R+ D D SG + + E++ L++ K + +A Sbjct: 604 Q---------------KYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVAR 648 Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 + D L ++ R L E K F+ D + G Sbjct: 649 FADDQL---------IIDFDNFVRCLVRLET--------------LFKIFKQLDPENTGT 685 Query: 206 ID 207 I+ Sbjct: 686 IE 687 Score = 33.6 bits (75), Expect = 0.090, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 52/127 (40%), Gaps = 8/127 (6%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQ--------ARKKAGLEL 54 ++S + + D+DGSG L KE L ++Q+ ++G Sbjct: 563 RQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMN 622 Query: 55 SPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDH 114 S EM+ +++ G + ++ V +A + + L E K +++ D ++ Sbjct: 623 SYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPEN 682 Query: 115 SGFIETE 121 +G IE + Sbjct: 683 TGTIELD 689 >2M8U-A nrPDB Length = 77 Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 33/78 (42%), Gaps = 8/78 (10%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 + + + ++ ++ +D D +G++ + L+ L +L D A+ + M+ Sbjct: 4 MNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELG--------DMMPADEIEEMIYE 55 Query: 154 FDSNNDGKLELTEMARLL 171 D N G ++ +L Sbjct: 56 ADPQNSGYVQYETFVGML 73 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 32/71 (45%), Gaps = 6/71 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T +Q E + FD DG+GY+ L+ ++ EL + + E++ + + ++ G Sbjct: 9 TKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELG------DMMPADEIEEMIYEADPQNSG 62 Query: 72 KIGIVELAHVL 82 + +L Sbjct: 63 YVQYETFVGML 73 Score = 37.5 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGK 246 + +AF+++D+DGNGY+ + L +L +L + + + I + G Sbjct: 9 TKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDM----MPADEIEEMIYEADPQNSGYV 64 Query: 247 LYRTDLALIL 256 Y T + ++ Sbjct: 65 QYETFVGMLF 74 >1RTP-1 nrPDB Length = 109 Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + KS ++ K + D D SGFIE +EL + LK A A+ T ++ D Sbjct: 36 KKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLS-----AKETKTLMAAGD 90 Query: 156 SNNDGKLELTEMARLLP 172 + DGK+ + E + L+ Sbjct: 91 KDGDGKIGVEEFSTLVA 107 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 35/74 (47%), Gaps = 3/74 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 +A +++ D D SG++E EL ++++ + + E KT + + DG Sbjct: 39 SADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAK---ETKTLMAAGDKDGDG 95 Query: 72 KIGIVELAHVLPTE 85 KIG+ E + ++ Sbjct: 96 KIGVEEFSTLVAES 109 Score = 28.6 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 28/78 (35%), Gaps = 5/78 (6%) Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD 199 K A+ + + D + G +E E+ +L + KE D Sbjct: 36 KKKSADDVKKVFHILDKDKSGFIEEDELGSILK-----GFSSDARDLSAKETKTLMAAGD 90 Query: 200 QDGNGYIDENELDALLKD 217 +DG+G I E L+ + Sbjct: 91 KDGDGKIGVEEFSTLVAE 108 Score = 26.7 bits (57), Expect = 10.0, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 176 NFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYK 235 F K + K F + D+D +G+I+E+EL ++LK + DL T Sbjct: 28 KFFQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDAR-DLSAKETKTLM 86 Query: 236 KNIMALSDG 244 DG Sbjct: 87 AAGDKDGDG 95 >1RK9-A nrPDB Length = 110 Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + KS ++ K + D D SGFIE +EL LK A A+ T +++ D Sbjct: 37 KKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLS-----AKETKMLMAAGD 91 Query: 156 SNNDGKLELTEMARLLP 172 + DGK+ + E + L+ Sbjct: 92 KDGDGKIGVDEFSTLVA 108 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 33/74 (44%), Gaps = 3/74 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 +A +++ D D SG++E EL +++ + + E K + + DG Sbjct: 40 SADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAK---ETKMLMAAGDKDGDG 96 Query: 72 KIGIVELAHVLPTE 85 KIG+ E + ++ Sbjct: 97 KIGVDEFSTLVAES 110 Score = 27.1 bits (58), Expect = 8.0, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 29/78 (37%), Gaps = 5/78 (6%) Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD 199 K A+ + + D + G +E E+ +L + KE D Sbjct: 37 KKKSADDVKKVFHMLDKDKSGFIEEDELGFILK-----GFSPDARDLSAKETKMLMAAGD 91 Query: 200 QDGNGYIDENELDALLKD 217 +DG+G I +E L+ + Sbjct: 92 KDGDGKIGVDEFSTLVAE 109 >5JOL-A nrPDB Length = 82 Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 4/81 (4%) Query: 90 LLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDL 149 + + E + + K DTD +G+I EL DL + A + ++ E T+ Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNEL----NDLFKAACLPLPGYRVREITEN 56 Query: 150 MLKLFDSNNDGKLELTEMARL 170 ++ D + DG++ E ++ Sbjct: 57 LMATGDLDQDGRISFDEFIKI 77 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 29/81 (35%), Gaps = 4/81 (4%) Query: 1 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKT 60 MA + + + E + D DG+GY+ EL +L + G + + Sbjct: 1 MARGSVSDEEM--MELREAFAKVDTDGNGYISFNELNDLFKA--ACLPLPGYRVREITEN 56 Query: 61 FVDQYGQRDDGKIGIVELAHV 81 + DG+I E + Sbjct: 57 LMATGDLDQDGRISFDEFIKI 77 Score = 35.2 bits (79), Expect = 0.033, Method: Composition-based stats. Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 4/54 (7%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 E +AF D DGNGYI NEL+ L K C L + +N+MA D Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC----LPLPGYRVREITENLMATGD 62 Score = 27.9 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 5/85 (5%) Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNK 193 A +V D ++ E + K D++ +G + E+ L L ++ ++ Sbjct: 2 ARGSVSDEEMMELREAFAK-VDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60 Query: 194 AFELYDQDGNGYIDENELDALLKDL 218 D D +G I +E + L Sbjct: 61 G----DLDQDGRISFDEFIKIFHGL 81 >3I5I-C nrPDB Length = 159 Score = 51.0 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 64/160 (40%), Gaps = 21/160 (13%) Query: 12 TASQFFEIWLHFDA-DG-SGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 + E++ FD DG G ++ ++ +L++ L +A + K ++ Sbjct: 7 EIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQHGGTKKMGEKA---- 62 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 +L +LP E + + +EFM+ ++ +D + G I + E++N LK Sbjct: 63 ------YKLEEILPIYEE---MSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKM 113 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 L E+ + + + DG ++ ++ + Sbjct: 114 LGERITEDQCNDIFT------FCDIREDIDGNIKYEDLMK 147 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 59/165 (35%), Gaps = 19/165 (11%) Query: 97 LKSCEEFMKTWRKYD--TDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLF 154 EE + + +D G ++ ++ + L+ L + Sbjct: 5 KDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQHGGTK-------- 56 Query: 155 DSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 + +L E+ + + + EF +AF+ +D++G G I E+ + Sbjct: 57 -KMGEKAYKLEEILPIYEE-----MSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNV 110 Query: 215 LKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDLALILCAG 259 LK L E+ + N+I T+ + G + DL + AG Sbjct: 111 LKMLGER-ITEDQCNDIFTF--CDIREDIDGNIKYEDLMKKVMAG 152 >5PAL-A nrPDB Length = 109 Score = 51.0 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + K+ + + + D D SGFIE EELK LK D T +L D Sbjct: 36 KGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTE-----TKALLAAGD 90 Query: 156 SNNDGKLELTEMARLLP 172 S++DGK+ E A+++ Sbjct: 91 SDHDGKIGADEFAKMVA 107 Score = 44.4 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 3/74 (4%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 T +Q E++ D D SG++E +EL+ +++ + E K + DG Sbjct: 39 TDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLN---DTETKALLAAGDSDHDG 95 Query: 72 KIGIVELAHVLPTE 85 KIG E A ++ Sbjct: 96 KIGADEFAKMVAQA 109 Score = 30.2 bits (66), Expect = 0.87, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 14/95 (14%) Query: 160 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 G + L+ ++ + + FE+ D+D +G+I+E EL +LK Sbjct: 22 GTFDYKRFFHLVGLKGK----------TDAQVKEVFEILDKDQSGFIEEEELKGVLKGFS 71 Query: 220 EKNKQDLDINNITTYKKNIMALSD-GGKLYRTDLA 253 + D+N+ T SD GK+ + A Sbjct: 72 AHGR---DLNDTETKALLAAGDSDHDGKIGADEFA 103 >5ZH6-A nrPDB Length = 107 Score = 51.0 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS K + D D SGFIE +ELK FL++ A + + T+ L DS+ Sbjct: 37 KSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDE-----TETNAFLAAGDSD 91 Query: 158 NDGKLELTEMARLLPV 173 +DGK+ + E ++ Sbjct: 92 HDGKIGVDEFKAMVKA 107 Score = 40.6 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 3/70 (4%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + +++ D D SG++E EL+ +Q ++ E F+ DGKI Sbjct: 40 ANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDE---TETNAFLAAGDSDHDGKI 96 Query: 74 GIVELAHVLP 83 G+ E ++ Sbjct: 97 GVDEFKAMVK 106 Score = 29.0 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 176 NFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYK 235 F + K F++ DQD +G+I+ +EL L++ + +LD + Sbjct: 27 TFFVTSGLTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATAR-ELDETETNAFL 85 Query: 236 KNIMALSDG 244 + DG Sbjct: 86 AAGDSDHDG 94 >5JOJ-A nrPDB Length = 97 Score = 51.0 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 4/81 (4%) Query: 90 LLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDL 149 + + E + + K DTD +G+I EL DL + A + ++ E T+ Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNEL----NDLFKAACLPLPGYRVREITEN 56 Query: 150 MLKLFDSNNDGKLELTEMARL 170 ++ D + DG++ E ++ Sbjct: 57 LMATGDLDQDGRISFDEFIKI 77 Score = 38.7 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 29/81 (35%), Gaps = 4/81 (4%) Query: 1 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKT 60 MA + + + E + D DG+GY+ EL +L + G + + Sbjct: 1 MARGSVSDEEM--MELREAFAKVDTDGNGYISFNELNDLFKA--ACLPLPGYRVREITEN 56 Query: 61 FVDQYGQRDDGKIGIVELAHV 81 + DG+I E + Sbjct: 57 LMATGDLDQDGRISFDEFIKI 77 Score = 34.8 bits (78), Expect = 0.037, Method: Composition-based stats. Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 4/54 (7%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 E +AF D DGNGYI NEL+ L K C L + +N+MA D Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC----LPLPGYRVREITENLMATGD 62 Score = 27.5 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 5/85 (5%) Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNK 193 A +V D ++ E + K D++ +G + E+ L L ++ ++ Sbjct: 2 ARGSVSDEEMMELREAFAK-VDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60 Query: 194 AFELYDQDGNGYIDENELDALLKDL 218 D D +G I +E + L Sbjct: 61 G----DLDQDGRISFDEFIKIFHGL 81 >2E6W-A nrPDB Length = 100 Score = 51.0 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 31/80 (38%), Gaps = 4/80 (5%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKD----LLEKANKTVDDTKLAEYTDLMLKLFDS 156 E+ + YD + G+I EE+ +K + + + AE+ + + D Sbjct: 9 EKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDR 68 Query: 157 NNDGKLELTEMARLLPVQEN 176 N DG + + E EN Sbjct: 69 NQDGVVTIEEFLEACQKDEN 88 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 31/64 (48%), Gaps = 8/64 (12%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCE--------KNKQDLDINNITTYKKNIMA 240 ++ AF LYD + +GYI + E+ A++K + + ++D ++ + + + Sbjct: 9 EKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDR 68 Query: 241 LSDG 244 DG Sbjct: 69 NQDG 72 Score = 33.6 bits (75), Expect = 0.083, Method: Composition-based stats. Identities = 11/85 (12%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQEL------QQARKKAGLELSPEMKTFVDQYGQR 68 + + +D + GY+ +E+ +++ + + ++ F ++ + Sbjct: 10 KLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRN 69 Query: 69 DDGKIGIVELAHVLPTEENFLLLFR 93 DG + I E +EN + + Sbjct: 70 QDGVVTIEEFLEACQKDENIMSSMQ 94 >1OZS-A nrPDB Length = 73 Score = 51.0 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 8/77 (10%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + KS EE +R +D + G+I+ EELK L+ E + + + ++K D Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITE--------DDIEELMKDGD 53 Query: 156 SNNDGKLELTEMARLLP 172 NNDG+++ E + Sbjct: 54 KNNDGRIDYDEFLEFMK 70 Score = 36.7 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 + +++ FD + GY++ +EL+ ++Q + + +++ + + +DG+I Sbjct: 8 ELSDLFRMFDKNADGYIDLEELKIMLQATGETITED------DIEELMKDGDKNNDGRID 61 Query: 75 IVELAHVLPTEE 86 E + E Sbjct: 62 YDEFLEFMKGVE 73 Score = 31.3 bits (69), Expect = 0.44, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 33/77 (42%), Gaps = 8/77 (10%) Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYD 199 K E + ++FD N DG ++L E+ +L G + + + + D Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT--------GETITEDDIEELMKDGD 53 Query: 200 QDGNGYIDENELDALLK 216 ++ +G ID +E +K Sbjct: 54 KNNDGRIDYDEFLEFMK 70 Score = 30.2 bits (66), Expect = 0.83, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 4/58 (6%) Query: 187 CGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +E + F ++D++ +GYID EL +L+ E +D +I K+ +DG Sbjct: 5 SEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITED----DIEELMKDGDKNNDG 58 >4P5X-A nrPDB Length = 315 Score = 50.6 bits (119), Expect = 6e-07, Method: Composition-based stats. Identities = 30/211 (14%), Positives = 62/211 (29%), Gaps = 35/211 (16%) Query: 12 TASQFFEIWLHF---DADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQR 68 + I+L + + DG Y+ ++ + + L ++ Q Sbjct: 16 DPHELRNIFLQYASTEVDGERYMTPEDF--VQRYLG--LYNDPNSNPKIVQLLAGVADQT 71 Query: 69 DDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLK 128 DG I E +F ++ +D +G + E +K Sbjct: 72 KDGLISYQEFLAFESVLCAPDSMFIV-----------AFQLFDKSGNGEVTFENVKEIFG 120 Query: 129 DLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCG 188 + + E+ L F N L TE + L ++ Sbjct: 121 QTIIHH--HIPFNWDCEFIRL---HFGHNRKKHLNYTEFTQFLQ------------ELQL 163 Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLC 219 + +AF L D+ +G I + ++ + Sbjct: 164 EHARQAFALKDKSKSGMISGLDFSDIMVTIR 194 >2ZFD-A nrPDB Length = 226 Score = 50.2 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 68/165 (41%), Gaps = 10/165 (6%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + ++ + S+ ++ F S ++ + +E Q A K + S D + Sbjct: 38 RDTVFSVSEIEALYELFKKISSAVIDDGLINK--EEFQLALFKTNKKESLFADRVFDLFD 95 Query: 67 QRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 126 + +G +G E A L + ++ +++ YD GFIE +E+K Sbjct: 96 TKHNGILGFEEFARALSVFHPNAPID--------DKIHFSFQLYDLKQQGFIERQEVKQM 147 Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + L ++ + DT + + D + D+ +DGK++ E L+ Sbjct: 148 VVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 192 Score = 44.0 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 58/162 (35%), Gaps = 26/162 (16%) Query: 99 SCEEFMKTWRKYDTDH-----SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 S E + + G I EE + L +K + + D + L Sbjct: 43 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESL---------FADRVFDL 93 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 FD+ ++G L E AR L V F + + +F+LYD G+I+ E+ Sbjct: 94 FDTKHNGILGFEEFARALSV-------FHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 146 Query: 214 -LLKDLCEKNKQDLDI---NNITTYKKNIMALSDGGKLYRTD 251 ++ L E D + I + D GK+ + + Sbjct: 147 MVVATLAESGMNLKDTVIEDIIDKTFEEADTKHD-GKIDKEE 187 >5YPX-A nrPDB Length = 223 Score = 50.2 bits (118), Expect = 8e-07, Method: Composition-based stats. Identities = 26/129 (20%), Positives = 47/129 (36%), Gaps = 12/129 (9%) Query: 128 KDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMC 187 ++L + D + + FD ++D + LTE L V L Sbjct: 64 RNLFRDILHQKFNMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLD------- 116 Query: 188 GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLD----INNITTYKKNIMALSD 243 ++ F ++D +G+GYI E+ +LK K + D I ++ M Sbjct: 117 -EKMEYTFTVFDLNGDGYISREEMFQMLKTCLVKQPTEEDPDEGIKDLVEIALKKMDHDH 175 Query: 244 GGKLYRTDL 252 +L + D Sbjct: 176 DSRLSKKDF 184 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 59/140 (42%), Gaps = 11/140 (7%) Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGF 117 M + + D I + E L +F L E+ T+ +D + G+ Sbjct: 83 MDRVFRAFDKDSDSYISLTEWVEGLS-------VFLRGTLDEKMEY--TFTVFDLNGDGY 133 Query: 118 IETEELKNFLKD-LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 I EE+ LK L+++ + D + + ++ LK D ++D +L + + + E Sbjct: 134 ISREEMFQMLKTCLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAV-LIEP 192 Query: 177 FLLKFQGIKMCGKEFNKAFE 196 LL+ G + ++ ++ FE Sbjct: 193 LLLEAFGKCLPDEKSSEIFE 212 Score = 32.1 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 33/106 (31%), Gaps = 6/106 (5%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 ++ FD D Y+ E + + L +M+ + DG I E+ Sbjct: 86 VFRAFDKDSDSYISLTEWVEGLSVFLRG------TLDEKMEYTFTVFDLNGDGYISREEM 139 Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 +L T + +K D DH + ++ K Sbjct: 140 FQMLKTCLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFK 185 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 34/90 (37%), Gaps = 4/90 (4%) Query: 20 WLHFDADGSGYLEGKELQNLIQEL---QQARKKAGLELSPEMKTFVDQYGQRDDGKIGIV 76 + FD +G GY+ +E+ +++ Q + + ++ + + D ++ Sbjct: 123 FTVFDLNGDGYISREEMFQMLKTCLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKK 182 Query: 77 ELAHVLPTEENFLLLF-RCQQLKSCEEFMK 105 + + E L F +C + E + Sbjct: 183 DFKDAVLIEPLLLEAFGKCLPDEKSSEIFE 212 >3I5H-B nrPDB Length = 153 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 48/125 (38%), Gaps = 19/125 (15%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + +E + + D D GFI E+LK+ L + + MLK Sbjct: 11 SQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVP--------PDDELNAMLKEC- 61 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 G+L T L + + AF ++D+DG G+I E+ L LL Sbjct: 62 ---PGQLNFTAFLTLFGEKVSGT-------DPEDALRNAFSMFDEDGQGFIPEDYLKDLL 111 Query: 216 KDLCE 220 +++ + Sbjct: 112 ENMGD 116 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 16/129 (12%), Positives = 43/129 (33%), Gaps = 18/129 (13%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + E + D D G++ ++L+++ L + ++ + G+ Sbjct: 15 MQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPP----------DDELNAMLKECPGQ 64 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + + + + +D D GFI + LK+ L+++ + Sbjct: 65 LNFTAFLTLFGE--------KVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGD 116 Query: 133 KANKTVDDT 141 +K Sbjct: 117 NFSKEEIKN 125 >5H53-B nrPDB Length = 146 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 30/160 (18%), Positives = 59/160 (36%), Gaps = 23/160 (14%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 +EF + + D + G I+ E+L++ + K E D M+K G Sbjct: 5 QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKN-------EELDAMMKEA----SG 53 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + T + + AF++ D +G G I + L+ LL C+ Sbjct: 54 PINFTVFLTMFGEKLKG-------ADPEDVITGAFKVLDPEGKGTIKKQFLEELLITQCD 106 Query: 221 KNKQDLDINNITTYKKNIMALSDGGKLYRTDLALILCAGD 260 + Q+ N + ++ GG + ++ ++ GD Sbjct: 107 RFSQEEIKNMWAAFSPDV-----GGNVDYKNICYVITHGD 141 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 21/160 (13%), Positives = 51/160 (31%), Gaps = 25/160 (15%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 +F E + D + G ++ ++L++ + + K + E+ + + G Sbjct: 4 IQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVK-----NEELDAMMKEA----SGP 54 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 I + + + + ++ D + G I+ K LE Sbjct: 55 INFTVFLTMFGE--------KLKGADPEDVITGAFKVLDPEGKGTIK--------KQFLE 98 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 + T D E M F + G ++ + ++ Sbjct: 99 ELLITQCDRFSQEEIKNMWAAFSPDVGGNVDYKNICYVIT 138 >1DGU-A nrPDB Length = 183 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDL-LEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 164 +R +D D G + E+L + L E + + +++ + D +L+ D + DG + L Sbjct: 103 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 162 Query: 165 TEMARLLPVQENFLLKFQ 182 +E ++ +F F+ Sbjct: 163 SEFQHVISRSPDFASSFK 180 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 3/78 (3%) Query: 19 IWLHFDADGSGYLEGKELQNLIQEL---QQARKKAGLELSPEMKTFVDQYGQRDDGKIGI 75 + FD D G L ++L L+ L + + + E+ + +++ DG I + Sbjct: 103 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 162 Query: 76 VELAHVLPTEENFLLLFR 93 E HV+ +F F+ Sbjct: 163 SEFQHVISRSPDFASSFK 180 Score = 37.1 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 38/100 (38%), Gaps = 11/100 (11%) Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL-CE 220 L + LL V F + + AF ++D D +G ++ +L L+ L E Sbjct: 78 LSFEDFLDLLSV-------FSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 130 Query: 221 KNKQDLDINNITTYKKNIMALSD---GGKLYRTDLALILC 257 L + + NI+ SD G + ++ ++ Sbjct: 131 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 170 >2N8Y-A nrPDB Length = 153 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 37/111 (33%), Gaps = 10/111 (9%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 +F + HFD D SG L +E + + L + E + G + Sbjct: 11 EFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGN-DPQGEAEFARIMSIVDPNRLGVVT 69 Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 + E + ++ M +++ D + +I +EL+ Sbjct: 70 FQAFIDFMSRET--------ADTDTADQVMASFKILAGDKN-YITMDELRR 111 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 42/117 (35%), Gaps = 11/117 (9%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 + EF ++ +D DHSG + EE K L L D AE+ ++ + D Sbjct: 5 SQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIG--NDPQGEAEFA-RIMSIVD 61 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELD 212 N G + + + + +F++ D N YI +EL Sbjct: 62 PNRLGVVTFQAFIDFMS-------RETADTDTADQVMASFKILAGDKN-YITMDELR 110 Score = 29.8 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 15/30 (50%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLC 219 EF +F +D+D +G + E A L L Sbjct: 11 EFRASFNHFDRDHSGTLGPEEFKACLISLG 40 >1G33-A nrPDB Length = 73 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 5/75 (6%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS ++ K + D D SGFIE +EL + LK A A+ T ++ D + Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLS-----AKETKTLMAAGDKD 56 Query: 158 NDGKLELTEMARLLP 172 DGK+ + E + L+ Sbjct: 57 GDGKIGVEEFSTLVA 71 Score = 40.6 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 10 LITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 + +A +++ D D SG++E EL ++++ + + E KT + + Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAK---ETKTLMAAGDKDG 57 Query: 70 DGKIGIVELAHVLPTE 85 DGKIG+ E + ++ Sbjct: 58 DGKIGVEEFSTLVAES 73 Score = 27.5 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 28/76 (36%), Gaps = 5/76 (6%) Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 K A+ + + D + G +E E+ +L + KE D+D Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILK-----GFSSDARDLSAKETKTLMAAGDKD 56 Query: 202 GNGYIDENELDALLKD 217 G+G I E L+ + Sbjct: 57 GDGKIGVEEFSTLVAE 72 >3PAT-A nrPDB Length = 110 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 5/73 (6%) Query: 99 SCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNN 158 S + K ++ D D SGFIE EELK LK D T LK D + Sbjct: 40 SANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAE-----TKAFLKAADKDG 94 Query: 159 DGKLELTEMARLL 171 DGK+ + E L+ Sbjct: 95 DGKIGIDEFETLV 107 Score = 40.2 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 11 ITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 ++A+ +++ DAD SG++E +EL+ +++ + E K F+ + D Sbjct: 39 MSANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRD---LTDAETKAFLKAADKDGD 95 Query: 71 GKIGIVELAHVLPTE 85 GKIGI E ++ Sbjct: 96 GKIGIDEFETLVHEA 110 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 24/60 (40%), Gaps = 1/60 (1%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 M + K F+ D D +G+I+E EL +LK + D + K DG Sbjct: 38 AMSANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDA-ETKAFLKAADKDGDG 96 Score = 27.1 bits (58), Expect = 8.4, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 29/72 (40%), Gaps = 5/72 (6%) Query: 144 AEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGN 203 A + K D++ G +E E+ +L G + E + D+DG+ Sbjct: 41 ANDVKKVFKAIDADASGFIEEEELKFVLK-----SFAADGRDLTDAETKAFLKAADKDGD 95 Query: 204 GYIDENELDALL 215 G I +E + L+ Sbjct: 96 GKIGIDEFETLV 107 >1QX2-A nrPDB Length = 76 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 30/78 (38%), Gaps = 8/78 (10%) Query: 98 KSCEEFMKTWRKYD-TDHS-GFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 KS EE + + + I EELK ++ L K + D M++ D Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMST------LDEMIEEVD 55 Query: 156 SNNDGKLELTEMARLLPV 173 N DG++ E ++ Sbjct: 56 KNGDGEVSFEEFLVMMKK 73 Score = 36.0 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 10/77 (12%), Positives = 31/77 (40%), Gaps = 6/77 (7%) Query: 10 LITASQFFEIWLHFD-ADGSGY-LEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 + + + + F +G + +EL+ ++Q L + L+ + +++ + Sbjct: 1 MKSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSL----LKGMSTLDEMIEEVDK 56 Query: 68 RDDGKIGIVELAHVLPT 84 DG++ E ++ Sbjct: 57 NGDGEVSFEEFLVMMKK 73 >1UHN-A nrPDB Length = 189 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 68/165 (41%), Gaps = 10/165 (6%) Query: 7 QSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYG 66 + ++ + S+ ++ F S ++ + +E Q A K + S D + Sbjct: 7 RDTVFSVSEIEALYELFKKISSAVIDDGLINK--EEFQLALFKTNKKESLFADRVFDLFD 64 Query: 67 QRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 126 + +G +G E A L + ++ +++ YD GFIE +E+K Sbjct: 65 TKHNGILGFEEFARALSVFHPNAPID--------DKIHFSFQLYDLKQQGFIERQEVKQM 116 Query: 127 LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + L ++ + DT + + D + D+ +DGK++ E L+ Sbjct: 117 VVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLV 161 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 58/161 (36%), Gaps = 24/161 (14%) Query: 99 SCEEFMKTWRKYDTDH-----SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 S E + + G I EE + L +K + + D + L Sbjct: 12 SVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESL---------FADRVFDL 62 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 FD+ ++G L E AR L V F + + +F+LYD G+I+ E+ Sbjct: 63 FDTKHNGILGFEEFARALSV-------FHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQ 115 Query: 214 LLKDLCEKNKQDLDINNITTYKKNIMALSD---GGKLYRTD 251 ++ ++ +L I +D GK+ + + Sbjct: 116 MVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEE 156 >5OTJ-D nrPDB Length = 110 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 31/69 (44%), Gaps = 9/69 (13%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 ++ + ++++DT+ G I EL + L+ L + A+ M+ D++ D Sbjct: 2 ADDMERIFKRFDTNGDGKISLSELTDALRTLGSTS---------ADEVQRMMAEIDTDGD 52 Query: 160 GKLELTEMA 168 G ++ E Sbjct: 53 GFIDFNEFI 61 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 7/69 (10%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 A I+ FD +G G + EL + ++ L + E++ + + DG Sbjct: 2 ADDMERIFKRFDTNGDGKISLSELTDALRTLGST-------SADEVQRMMAEIDTDGDGF 54 Query: 73 IGIVELAHV 81 I E Sbjct: 55 IDFNEFISF 63 Score = 34.8 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 9/68 (13%) Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDG 202 +A+ + + K FD+N DGK+ L+E+ L E + D DG Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALR---------TLGSTSADEVQRMMAEIDTDG 51 Query: 203 NGYIDENE 210 +G+ID NE Sbjct: 52 DGFIDFNE 59 Score = 31.3 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 22/56 (39%), Gaps = 5/56 (8%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 + + F+ +D +G+G I +EL L+ L + + I DG Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLG-----STSADEVQRMMAEIDTDGDG 53 Score = 30.2 bits (66), Expect = 0.94, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 10/70 (14%) Query: 54 LSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTD 113 ++ +M+ ++ DGKI + EL L T + S +E + + DTD Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALRTLGST----------SADEVQRMMAEIDTD 50 Query: 114 HSGFIETEEL 123 GFI+ E Sbjct: 51 GDGFIDFNEF 60 >2LM5-A nrPDB Length = 214 Score = 49.1 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 106 TWRKYDTDHSGFIETEELKNFLKDL-LEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLEL 164 +R +D D G + E+L + L E + + +++ + D +L+ D + DG + L Sbjct: 134 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 193 Query: 165 TEMARLLPVQENFLLKFQ 182 +E ++ +F F+ Sbjct: 194 SEFQHVISRSPDFASSFK 211 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 3/78 (3%) Query: 19 IWLHFDADGSGYLEGKELQNLIQEL---QQARKKAGLELSPEMKTFVDQYGQRDDGKIGI 75 + FD D G L ++L L+ L + + + E+ + +++ DG I + Sbjct: 134 AFRIFDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINL 193 Query: 76 VELAHVLPTEENFLLLFR 93 E HV+ +F F+ Sbjct: 194 SEFQHVISRSPDFASSFK 211 Score = 36.3 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 38/100 (38%), Gaps = 11/100 (11%) Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL-CE 220 L + LL V F + + AF ++D D +G ++ +L L+ L E Sbjct: 109 LSFEDFLDLLSV-------FSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGE 161 Query: 221 KNKQDLDINNITTYKKNIMALSD---GGKLYRTDLALILC 257 L + + NI+ SD G + ++ ++ Sbjct: 162 GEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVIS 201 >3KPX-A nrPDB Length = 198 Score = 48.7 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 53/160 (33%), Gaps = 16/160 (10%) Query: 17 FEIWLHFDADGSGYLEGKELQN-----LIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ D +G+G + E+ + + +L + ++ F + G Sbjct: 26 KFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQ-RHQEAVEAFFKKIGLDYGK 84 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKS--CEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 ++ + L Q KS + +D D SG I +E K + Sbjct: 85 EVEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEWKTYGGI 144 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + E + K D +N GKL++ EM R Sbjct: 145 SGICPSD--------EDAEKTFKHCDLDNSGKLDVDEMTR 176 Score = 42.9 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 59/157 (37%), Gaps = 12/157 (7%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTW-RKYDTDHSGF 117 K + +GKI + E+ + L Q + +E ++ + +K D+ Sbjct: 26 KFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKE 85 Query: 118 IETEELKNFLKDLLEKANKTVDDTKLA---EYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 +E N K+L + K K + + + + +FD + G + L E Sbjct: 86 VEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEWKT----- 140 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 GI ++ K F+ D D +G +D +E+ Sbjct: 141 ---YGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEM 174 >2K2A-A nrPDB Length = 70 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 36/73 (49%), Gaps = 8/73 (10%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 +E + +R YD + +G+I T+ ++ L +L D+T +E D M+ D++ Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAEL--------DETLSSEDLDAMIDEIDADGS 53 Query: 160 GKLELTEMARLLP 172 G ++ E ++ Sbjct: 54 GTVDFEEFMGVMT 66 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 30/74 (40%), Gaps = 6/74 (8%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + +D +G+GY+ ++ ++ EL + S ++ +D+ G + Sbjct: 3 QELREAFRLYDKEGNGYISTDVMREILAELDETLS------SEDLDAMIDEIDADGSGTV 56 Query: 74 GIVELAHVLPTEEN 87 E V+ + Sbjct: 57 DFEEFMGVMTGGDE 70 Score = 35.6 bits (80), Expect = 0.022, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%) Query: 188 GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 +E +AF LYD++GNGYI + + +L +L E L ++ I A G Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAELDE----TLSSEDLDAMIDEIDADGSG 54 >1DFK-Y nrPDB Length = 139 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 18/160 (11%), Positives = 51/160 (31%), Gaps = 27/160 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + E + D D G++ ++++ + ++L +A + + G Sbjct: 6 IQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPD----------DKELTAMLKEAPGP 55 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + + S E + +D + + E +K+ L+++ + Sbjct: 56 LNFTMFLSIFSD--------KLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGD 107 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 NK + + K GK + + ++ Sbjct: 108 NFNK--------DEMRMTFKEAPVEG-GKFDYVKFTAMIK 138 Score = 41.4 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 43/125 (34%), Gaps = 19/125 (15%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 K +E + + D D GF+ E++K + L + + MLK Sbjct: 2 PQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDD--------KELTAMLKEA- 52 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 G L T + + + + AF ++D+ ++ + LL Sbjct: 53 ---PGPLNFTMFLSIFSDKLSGT-------DSEETIRNAFAMFDEQETKKLNIEYIKDLL 102 Query: 216 KDLCE 220 +++ + Sbjct: 103 ENMGD 107 >5Z1Q-A nrPDB Length = 95 Score = 48.3 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FD + +G ++ EL+ ++ L KK PE+ +++Y + +G I Sbjct: 27 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKK------PEILELMNEYDREGNGYI 80 Query: 74 GIVELAHVLPTE 85 G + ++ + Sbjct: 81 GFDDFLDIMTEK 92 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +DT+ +G I+ ELK ++ L D K E +LM +D Sbjct: 24 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALG-------FDVKKPEILELM-NEYDRE 75 Query: 158 NDGKLELTEMARLLPVQ 174 +G + + ++ + Sbjct: 76 GNGYIGFDDFLDIMTEK 92 Score = 33.6 bits (75), Expect = 0.078, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 32/77 (41%), Gaps = 8/77 (10%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 + + LFD+N G ++ E+ + + G + E + YD+ Sbjct: 23 EEQKQEIKEAFDLFDTNKTGSIDYHELKVAM--------RALGFDVKKPEILELMNEYDR 74 Query: 201 DGNGYIDENELDALLKD 217 +GNGYI ++ ++ + Sbjct: 75 EGNGYIGFDDFLDIMTE 91 Score = 29.8 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 162 LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 ++ E + P ++ ++ + + +E +AF+L+D + G ID +EL ++ L Sbjct: 2 IKKPEFGLMQPPKKR--VRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALG 57 >2HPS-A nrPDB Length = 186 Score = 48.3 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 22/169 (13%), Positives = 52/169 (30%), Gaps = 9/169 (5%) Query: 1 MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKT 60 M E + D G G++ ++ + + + + K + + + Sbjct: 1 MPEITESERAYHLRKMKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQE 60 Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCE-EFMKTWRKYDTDHSGFIE 119 F+ Q + + + LL + ++ + + + DTD G++ Sbjct: 61 FLRVADQLGLAPGVRISVEEAAVNATDSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVS 120 Query: 120 TEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMA 168 E K FL+ + + D N +G++ E Sbjct: 121 LPEFKAFLQAVGPDLTD--------DKAITCFNTLDFNKNGQISRDEFL 161 Score = 36.7 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 51/153 (33%), Gaps = 9/153 (5%) Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGF 117 MKT + + DG I + + L + ++ +EF++ + Sbjct: 16 MKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVR 75 Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 I EE D L K + + +M D++ DG + L E Sbjct: 76 ISVEEAAVNATDSLLKMKGEEKAMAVIQSL-IMYDCIDTDKDGYVSLPEFKA-------- 126 Query: 178 LLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 L+ G + + F D + NG I +E Sbjct: 127 FLQAVGPDLTDDKAITCFNTLDFNKNGQISRDE 159 Score = 30.6 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 43/120 (35%), Gaps = 6/120 (5%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG-- 160 ++ D GFI E+ + + + A + K E L++ D Sbjct: 16 MKTRMQRVDVTGDGFISREDYELIAVRIAKIAK--LSAEKAEETRQEFLRVADQLGLAPG 73 Query: 161 -KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 ++ + E A + +K + M + ++ D D +GY+ E A L+ + Sbjct: 74 VRISVEE-AAVNATDSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVG 132 >1B7T-Y nrPDB Length = 156 Score = 48.3 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 18/160 (11%), Positives = 51/160 (31%), Gaps = 27/160 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + E + D D G++ ++++ + ++L +A + + G Sbjct: 17 IQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPD----------DKELTAMLKEAPGP 66 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + + S E + +D + + E +K+ L+++ + Sbjct: 67 LNFTMFLSIFSD--------KLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGD 118 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 NK + + K GK + + ++ Sbjct: 119 NFNK--------DEMRMTFKEAPVEG-GKFDYVKFTAMIK 149 Score = 41.0 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 43/125 (34%), Gaps = 19/125 (15%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 K +E + + D D GF+ E++K + L + + MLK Sbjct: 13 PQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDD--------KELTAMLKEA- 63 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 G L T + + + + AF ++D+ ++ + LL Sbjct: 64 ---PGPLNFTMFLSIFSDKLSGT-------DSEETIRNAFAMFDEQETKKLNIEYIKDLL 113 Query: 216 KDLCE 220 +++ + Sbjct: 114 ENMGD 118 >1C7W-A nrPDB Length = 81 Score = 48.3 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 EE ++ ++ +D + G I+ +E K ++ + E+ + +K D Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEP-------LTDAEVEEAMKEADE 56 Query: 157 NNDGKLELTEMARLLPVQENFLLK 180 + +G +++ E L+ +N L + Sbjct: 57 DGNGVIDIPEFMDLIKKSKNALKE 80 Score = 40.6 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 7/76 (9%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 E K+FD+N DG ++ E ++ K + E +A + D+ Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQ-------KVGEEPLTDAEVEEAMKEADE 56 Query: 201 DGNGYIDENELDALLK 216 DGNG ID E L+K Sbjct: 57 DGNGVIDIPEFMDLIK 72 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 34/79 (43%), Gaps = 5/79 (6%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + + FDA+G G ++ E + ++Q++ + E++ + + + +G Sbjct: 6 DEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEP-----LTDAEVEEAMKEADEDGNG 60 Query: 72 KIGIVELAHVLPTEENFLL 90 I I E ++ +N L Sbjct: 61 VIDIPEFMDLIKKSKNALK 79 Score = 30.6 bits (67), Expect = 0.69, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 27/44 (61%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDI 228 + +E +AF+++D +G+G ID +E +++ + E+ D ++ Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEV 47 Score = 27.9 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 25/64 (39%), Gaps = 8/64 (12%) Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + DG I E F++ ++ + E + ++ D D +G I+ E Sbjct: 17 FDANGDGVIDFDEF--------KFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEFM 68 Query: 125 NFLK 128 + +K Sbjct: 69 DLIK 72 >1JUO-A nrPDB Length = 198 Score = 47.9 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 39/124 (31%), Gaps = 17/124 (13%) Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 G I+ +EL+ L + E LM+ + D + G + E L V Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFN---LETCRLMVSMLDRDMSGTMGFNEFKELWAV 101 Query: 174 QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITT 233 + + F +D D +G +D EL L + + + Sbjct: 102 LNGW--------------RQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKR 147 Query: 234 YKKN 237 Y N Sbjct: 148 YSTN 151 Score = 44.4 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 54/146 (36%), Gaps = 32/146 (21%) Query: 27 GSGYLEGKELQNLIQELQQARKKAGLELSPEMKT---FVDQYGQRDDGKIGIVELAHVLP 83 G ++ ELQ + + AG ++T V + G +G E Sbjct: 45 QDGQIDADELQRCLTQSG----IAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF----- 95 Query: 84 TEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKL 143 +E + +L + + + +DTD SG ++ +EL+ L + + + Sbjct: 96 -KELWAVLNG---------WRQHFISFDTDRSGTVDPQELQKALTTMGFRLS-------- 137 Query: 144 AEYTDLMLKLFDSNNDGKLELTEMAR 169 + + + K + +N GK+ + Sbjct: 138 PQAVNSIAKRYSTN--GKITFDDYIA 161 Score = 29.4 bits (64), Expect = 1.4, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 33/101 (32%), Gaps = 18/101 (17%) Query: 8 SSLITASQFFEIWLH----------FDADGSGYLEGKELQNLIQELQQARKKAGLELSPE 57 S + ++F E+W FD D SG ++ +ELQ + + Sbjct: 87 SGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLS------PQA 140 Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLK 98 + + +Y +GKI + FR + Sbjct: 141 VNSIAKRYST--NGKITFDDYIACCVKLRALTDSFRRRDTA 179 >2EC6-B nrPDB Length = 133 Score = 47.5 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 18/160 (11%), Positives = 47/160 (29%), Gaps = 27/160 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + E + D + G+++ +L+ L + + + G Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPD----------DKELTAMLKEAPGP 50 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + + S E + +D D + + E +K+ L+++ + Sbjct: 51 LNFTMFLSIFSD--------KLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGD 102 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 NK + + K GK + ++ Sbjct: 103 NFNK--------DEMRMTFKEAPVEG-GKFDYVRFVAMIK 133 Score = 41.0 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 42/121 (34%), Gaps = 19/121 (15%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 +E + + D + GFI+ +LK L + + MLK Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDD--------KELTAMLKEA----P 48 Query: 160 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 G L T + + + + AF ++D+D ++ + LL+++ Sbjct: 49 GPLNFTMFLSIFSDKLSGT-------DSEETIRNAFGMFDEDATKKLNIEYIKDLLENMG 101 Query: 220 E 220 + Sbjct: 102 D 102 >1YX7-A nrPDB Length = 83 Score = 47.5 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 E ++K D + G++ EL+ F+ L K + K+ E + ++K+ D N+DGK Sbjct: 8 ELEAAFKKLDANGDGYVTALELQTFMVTLDAY--KALSKDKVKEASAKLIKMADKNSDGK 65 Query: 162 LELTEMARL 170 + E Sbjct: 66 ISKEEFLNA 74 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 27/68 (39%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 ++ + DA+G GY+ ELQ + L + + ++ + + DGKI Sbjct: 7 AELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKI 66 Query: 74 GIVELAHV 81 E + Sbjct: 67 SKEEFLNA 74 Score = 31.7 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 29/71 (40%), Gaps = 3/71 (4%) Query: 53 ELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDT 112 ++ E++ + DG + +EL + T + + L + + ++ K + D Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEAS---AKLIKMADK 60 Query: 113 DHSGFIETEEL 123 + G I EE Sbjct: 61 NSDGKISKEEF 71 Score = 30.6 bits (67), Expect = 0.77, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 24/67 (35%), Gaps = 3/67 (4%) Query: 188 GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLD--INNITTYKKNIMALSDGG 245 E AF+ D +G+GY+ EL + L D K SD G Sbjct: 6 KAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSD-G 64 Query: 246 KLYRTDL 252 K+ + + Sbjct: 65 KISKEEF 71 Score = 27.1 bits (58), Expect = 8.8, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQD 201 K+ + K D+N DG + E+ + + + + + K ++ D++ Sbjct: 4 KVKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKV--KEASAKLIKMADKN 61 Query: 202 GNGYIDENELDA 213 +G I + E Sbjct: 62 SDGKISKEEFLN 73 >1JFJ-A nrPDB Length = 134 Score = 47.1 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 53/152 (34%), Gaps = 24/152 (15%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE 77 ++ D +G G + +E++ + KK ++ ++ +G+I E Sbjct: 4 ALFKEIDVNGDGAVSYEEVKAFVS------KKRAIKNEQLLQLIFKSIDADGNGEIDQNE 57 Query: 78 LAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKT 137 A + + L ++ D D G + EE+ +F K Sbjct: 58 FAKFYGSIQGQDL------SDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFK--------- 102 Query: 138 VDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + + + ++K D+N DG + L E Sbjct: 103 --KHGIEKVAEQVMK-ADANGDGYITLEEFLE 131 Score = 44.0 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 51/121 (42%), Gaps = 14/121 (11%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 +++ D + G + EE+K F+ K + L+ K D++ +G+++ E Sbjct: 6 FKEIDVNGDGAVSYEEVKAFV--------SKKRAIKNEQLLQLIFKSIDADGNGEIDQNE 57 Query: 167 MARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC-EKNKQD 225 A+ ++ Q + ++L D DG+G + + E+ + K EK + Sbjct: 58 FAKF-----YGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQ 112 Query: 226 L 226 + Sbjct: 113 V 113 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 55/156 (35%), Gaps = 26/156 (16%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 + + DG + E+ + + + +K+ + ++ D D +G I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKK---------RAIKNEQLLQLIFKSIDADGNGEI 53 Query: 119 ETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 + E F + + D + ++ KL D + DGKL E+ Sbjct: 54 DQNEFAKFY-----GSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKK----- 103 Query: 179 LKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDAL 214 GI+ ++ KA D +G+GYI E Sbjct: 104 ---HGIEKVAEQVMKA----DANGDGYITLEEFLEF 132 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 41/106 (38%), Gaps = 10/106 (9%) Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 + + K D N DG + E+ + + + F+ D DGNG I Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIK--------NEQLLQLIFKSIDADGNGEI 53 Query: 207 DENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDL 252 D+NE + ++ D I YK +M + GKL + ++ Sbjct: 54 DQNEFAKFYGSIQGQDLSDDKIGLKVLYK--LMDVDGDGKLTKEEV 97 Score = 32.5 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 36/108 (33%), Gaps = 16/108 (14%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 I+ DADG+G ++ E +Q + +D DGK Sbjct: 41 IFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDV---DGDGK------ 91 Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNF 126 L EE + K E+ MK D + G+I EE F Sbjct: 92 ---LTKEEVTSFFKKHGIEKVAEQVMKA----DANGDGYITLEEFLEF 132 >5MRA-A nrPDB Length = 167 Score = 47.1 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 39/124 (31%), Gaps = 17/124 (13%) Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 G I+ +EL+ L + E LM+ + D + G + E L V Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFN---LETCRLMVSMLDRDMSGTMGFNEFKELWAV 70 Query: 174 QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITT 233 + + F +D D +G +D EL L + + + Sbjct: 71 LNGW--------------RQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKR 116 Query: 234 YKKN 237 Y N Sbjct: 117 YSTN 120 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 23/146 (15%), Positives = 50/146 (34%), Gaps = 32/146 (21%) Query: 27 GSGYLEGKELQNLIQELQQARKKAGLELSPEMKT---FVDQYGQRDDGKIGIVELAHVLP 83 G ++ ELQ + + AG ++T V + G +G E + Sbjct: 14 QDGQIDADELQRCLTQSG----IAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWA 69 Query: 84 TEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKL 143 + + + +DTD SG ++ +EL+ L + + + Sbjct: 70 VLNGW---------------RQHFISFDTDRSGTVDPQELQKALTTMGFRLS-------- 106 Query: 144 AEYTDLMLKLFDSNNDGKLELTEMAR 169 + + + K + +N GK+ + Sbjct: 107 PQAVNSIAKRYSTN--GKITFDDYIA 130 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 30/86 (34%), Gaps = 8/86 (9%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + + + ++ FD D SG ++ +ELQ + + + + +Y +GK Sbjct: 71 LNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLS------PQAVNSIAKRYST--NGK 122 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLK 98 I + FR + Sbjct: 123 ITFDDYIACCVKLRALTDSFRRRDTA 148 >1SR6-C nrPDB Length = 156 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 44/128 (34%), Gaps = 17/128 (13%) Query: 96 QLKSCEEFMKTWRKYD--TDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 ++ + +D G ++ +L + + L N +D T M Sbjct: 4 SQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLG--INPRNEDVFAVGGTHKM--- 58 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 + L E + + ++ +AF+ +D++G G+I EL Sbjct: 59 ----GEKSLPFEEFLPA------YEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRH 108 Query: 214 LLKDLCEK 221 +L L E+ Sbjct: 109 VLTALGER 116 Score = 35.2 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 32/78 (41%), Gaps = 4/78 (5%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 E + T + + E + FD +G G++ G EL++++ L + ++ ++ Sbjct: 73 EGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLSDEDVDEIIKLTDLQ 132 Query: 63 DQYGQRDDGKIGIVELAH 80 + +G + + Sbjct: 133 ----EDLEGNVKYEDFVK 146 >2LVK-A nrPDB Length = 77 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 31/69 (44%), Gaps = 9/69 (13%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 ++ + ++++DT+ G I EL + L+ L + A+ M+ D++ D Sbjct: 1 ADDMERIFKRFDTNGDGKISLSELTDALRTLGSTS---------ADEVQRMMAEIDTDGD 51 Query: 160 GKLELTEMA 168 G ++ E Sbjct: 52 GFIDFNEFI 60 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 7/69 (10%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 A I+ FD +G G + EL + ++ L + E++ + + DG Sbjct: 1 ADDMERIFKRFDTNGDGKISLSELTDALRTLGST-------SADEVQRMMAEIDTDGDGF 53 Query: 73 IGIVELAHV 81 I E Sbjct: 54 IDFNEFISF 62 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 9/67 (13%) Query: 144 AEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGN 203 A+ + + K FD+N DGK+ L+E+ L E + D DG+ Sbjct: 1 ADDMERIFKRFDTNGDGKISLSELTDALR---------TLGSTSADEVQRMMAEIDTDGD 51 Query: 204 GYIDENE 210 G+ID NE Sbjct: 52 GFIDFNE 58 Score = 29.8 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 22/56 (39%), Gaps = 5/56 (8%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 + + F+ +D +G+G I +EL L+ L + + I DG Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLG-----STSADEVQRMMAEIDTDGDG 52 Score = 28.3 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 10/67 (14%) Query: 57 EMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116 +M+ ++ DGKI + EL L T + S +E + + DTD G Sbjct: 3 DMERIFKRFDTNGDGKISLSELTDALRTLGST----------SADEVQRMMAEIDTDGDG 52 Query: 117 FIETEEL 123 FI+ E Sbjct: 53 FIDFNEF 59 >1NYA-A nrPDB Length = 176 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 26/168 (15%), Positives = 57/168 (33%), Gaps = 20/168 (11%) Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWR-KYD----- 111 +K D++ +G + + + + + + +D Sbjct: 9 LKKRFDRWDFDGNGALERADFEK--EAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKE 66 Query: 112 --TDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 G + E+ ++L+ + + + L ++ + D N DG++ E A Sbjct: 67 AGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAA 126 Query: 170 LLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 L + M E +AF D +GNG + +EL ++D Sbjct: 127 WLTA----------LGMSKAEAAEAFNQVDTNGNGELSLDELLTAVRD 164 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 29/179 (16%), Positives = 54/179 (30%), Gaps = 20/179 (11%) Query: 11 ITASQFFEIWLHFDADGSGYLEG----KELQNLIQELQQARKKAGLELSPE-----MKTF 61 I + + + + +D DG+G LE KE Q++ + + A ++ Sbjct: 4 IASDRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYL 63 Query: 62 VDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETE 121 + G DG + + V F D + G I + Sbjct: 64 AKEAGVGSDGSLTEEQFIRV-TENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINAD 122 Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 180 E +L L + + D+N +G+L L E+ + L Sbjct: 123 EFAAWLTALGMSKAEAAEA----------FNQVDTNGNGELSLDELLTAVRDFHFGRLD 171 Score = 27.9 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 22/49 (44%) Query: 4 SHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGL 52 + L + ++ ++ E + D +G+G L EL +++ R L Sbjct: 126 AWLTALGMSKAEAAEAFNQVDTNGNGELSLDELLTAVRDFHFGRLDVEL 174 >2OS8-B nrPDB Length = 157 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 17/160 (10%), Positives = 47/160 (29%), Gaps = 27/160 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + E + D + G+++ +L+ + L + + + G Sbjct: 18 IQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPD----------DKELTAMLKEAPGP 67 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + + S E + +D + + E +K+ L+++ + Sbjct: 68 LNFTMFLSIFSD--------KLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGD 119 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 NK + + K GK + ++ Sbjct: 120 NFNK--------DEMRMTFKEAPVEG-GKFDYVRFVAMIK 150 Score = 40.2 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 42/125 (33%), Gaps = 19/125 (15%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 K +E + + D + GFI+ +LK L + + MLK Sbjct: 14 PQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDD--------KELTAMLKEA- 64 Query: 156 SNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 G L T + + + + AF ++D+ ++ + LL Sbjct: 65 ---PGPLNFTMFLSIFSDKLSGT-------DSEETIRNAFGMFDELDTKKLNIEYIKDLL 114 Query: 216 KDLCE 220 +++ + Sbjct: 115 ENMGD 119 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 24/49 (48%) Query: 171 LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 + + + + + +E +AF + DQ+ +G+ID N+L + L Sbjct: 1 MADKAASGVLTKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLG 49 >1S36-A nrPDB Length = 195 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 54/160 (33%), Gaps = 16/160 (10%) Query: 17 FEIWLHFDADGSGYLEGKELQN-----LIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ D +G+G + E+ + + +L+ ++ ++ F G Sbjct: 23 KHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTK-RHQVCVEAFFRGCGMEYGK 81 Query: 72 KIGIVELAHVLPTEENFLLLF--RCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 +I + L R + E + +D D SG I +E K + K Sbjct: 82 EIAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGKI 141 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + E + + D +N G L++ EM R Sbjct: 142 SGISPS--------QEDCEATFRHCDLDNSGDLDVDEMTR 173 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 59/166 (35%), Gaps = 30/166 (18%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTW----------- 107 K D +GKI + E+ + L +Q K + ++ + Sbjct: 23 KHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKE 82 Query: 108 RKYDTDHSGF--IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 165 + GF + T ELK + ++ + T + E+ D + +FD + G + L Sbjct: 83 IAFPQFLDGFKQLATSELKKWARN---------EPTLIREWGDAVFDIFDKDGSGTITLD 133 Query: 166 EMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 E + GI ++ F D D +G +D +E+ Sbjct: 134 EWKAYGKI--------SGISPSQEDCEATFRHCDLDNSGDLDVDEM 171 >3MSE-B nrPDB Length = 180 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 53/132 (40%), Gaps = 25/132 (18%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 + + K DT+H+G + E+ L + K + +L+ D N+ G + Sbjct: 41 INELFYKLDTNHNGSLSHREIYTVLASVGIKKWD----------INRILQALDINDRGNI 90 Query: 163 ELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKN 222 TE +N F AF D+D +GYI ++++ +L+ D Sbjct: 91 TYTEFMAGCYRWKNIESTF---------LKAAFNKIDKDEDGYISKSDIVSLVHD----- 136 Query: 223 KQDLDINNITTY 234 + LD N+I + Sbjct: 137 -KVLDNNDIDNF 147 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 16/106 (15%), Positives = 33/106 (31%), Gaps = 18/106 (16%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE 77 E++ D + +G L +E+ ++ + ++ + D G I E Sbjct: 43 ELFYKLDTNHNGSLSHREIYTVLASVGIK--------KWDINRILQALDINDRGNITYTE 94 Query: 78 LAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL 123 +N F + K D D G+I ++ Sbjct: 95 FMAGCYRWKNIESTF----------LKAAFNKIDKDEDGYISKSDI 130 >1JF0-A nrPDB Length = 195 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 55/160 (34%), Gaps = 16/160 (10%) Query: 17 FEIWLHFDADGSGYLEGKELQN-----LIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ + D +G+G + E+ + + + L + ++ F G Sbjct: 23 KFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQ-RHQDCVEAFFRGCGLEYGK 81 Query: 72 KIGIVELAHVLPTEENFLLLF--RCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 + E N L R + E + +D D SG I +E K + + Sbjct: 82 ETKFPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGRI 141 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 ++ E + + D +N G+L++ EM R Sbjct: 142 SGISPSE--------EDCEKTFQHCDLDNSGELDVDEMTR 173 Score = 42.1 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 60/159 (37%), Gaps = 16/159 (10%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 K D +G+I + E+ + L Q + ++ ++ + + + Sbjct: 23 KFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAF--FRGCGLEYG 80 Query: 119 ETEELKNFLKDLLEKANKTV------DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 + + FL+ AN + + T + E+ D + +FD + G + L E Sbjct: 81 KETKFPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKA--- 137 Query: 173 VQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 + GI ++ K F+ D D +G +D +E+ Sbjct: 138 -----YGRISGISPSEEDCEKTFQHCDLDNSGELDVDEM 171 >3TS5-B nrPDB Length = 161 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 17/160 (10%), Positives = 47/160 (29%), Gaps = 27/160 (16%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + E + D + G+++ +L+ + L + + + G Sbjct: 22 MQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPD----------DKELTAMLKEAPGP 71 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 + + + S E + +D + + E +K+ L+++ + Sbjct: 72 LNFTMFLSIFSD--------KLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGD 123 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLP 172 NK + + K GK + ++ Sbjct: 124 NFNK--------DEMRMTFKEAPVEG-GKFDYVRFVAMIK 154 Score = 41.0 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 44/130 (33%), Gaps = 19/130 (14%) Query: 91 LFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLM 150 +F K +E + + D + GFI+ +LK L + + M Sbjct: 13 VFARLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDD--------KELTAM 64 Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 LK G L T + + + + AF ++D+ ++ Sbjct: 65 LKEA----PGPLNFTMFLSIFSDKLSGT-------DSEETIRNAFGMFDELDTKKLNIEY 113 Query: 211 LDALLKDLCE 220 + LL+++ + Sbjct: 114 IKDLLENMGD 123 >1GJY-A nrPDB Length = 167 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 45/142 (31%), Gaps = 24/142 (16%) Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 G I+ +EL+ L + E LM+ + D + G + E L V Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFN---LETCRLMVSMLDRDMSGTMGFNEFKELWAV 70 Query: 174 QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITT 233 + + F +D D +G +D EL L + + +N+I Sbjct: 71 LNGW--------------RQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQ-TVNSIAK 115 Query: 234 YKKNIMALSDGGKLYRTDLALI 255 S GK+ D Sbjct: 116 ------RYSTSGKITFDDYIAC 131 Score = 41.0 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 22/146 (15%), Positives = 47/146 (32%), Gaps = 32/146 (21%) Query: 27 GSGYLEGKELQNLIQELQQARKKAGLELSPEMKT---FVDQYGQRDDGKIGIVELAHVLP 83 G ++ ELQ + + AG ++T V + G +G E + Sbjct: 14 QDGQIDADELQRCLTQSG----IAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWA 69 Query: 84 TEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKL 143 + + + +D+D SG ++ +EL+ L + + N ++ Sbjct: 70 VLNGW---------------RQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIA 114 Query: 144 AEYTDLMLKLFDSNNDGKLELTEMAR 169 Y+ GK+ + Sbjct: 115 KRYST----------SGKITFDDYIA 130 Score = 28.3 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 30/88 (34%), Gaps = 8/88 (9%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + + + ++ FD+D SG ++ +ELQ + + + + +Y GK Sbjct: 71 LNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLN------PQTVNSIAKRYST--SGK 122 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSC 100 I + FR + Sbjct: 123 ITFDDYIACCVKLRALTDSFRRRDSAQQ 150 >4D1E-A nrPDB Length = 876 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 16/111 (14%), Positives = 38/111 (34%), Gaps = 15/111 (13%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 +F + HFD +G ++ ++ + + + +A E + G + Sbjct: 739 EFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEA------EFARIMTLVDPNGQGTVT 792 Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 + E + E+ + ++R +D +I EEL+ Sbjct: 793 FQSFIDFMTRET--------ADTDTAEQVIASFRILASDKP-YILAEELRR 834 Score = 27.1 bits (58), Expect = 8.3, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 15/30 (50%) Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLC 219 EF +F +D+ NG +D + A L + Sbjct: 739 EFRASFNHFDRRKNGLMDHEDFRACLISMG 768 >2JOJ-A nrPDB Length = 77 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + E + FD + +G ++ EL+ ++ L KK PE+ +++Y + +G I Sbjct: 7 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKK------PEILELMNEYDREGNGYI 60 Query: 74 GIVELAHVLPTE 85 G + ++ + Sbjct: 61 GFDDFLDIMTEK 72 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + +E + + +DT+ +G I+ ELK ++ L D K E +LM +D Sbjct: 4 EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALG-------FDVKKPEILELM-NEYDRE 55 Query: 158 NDGKLELTEMARLLPVQ 174 +G + + ++ + Sbjct: 56 GNGYIGFDDFLDIMTEK 72 Score = 31.7 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 32/77 (41%), Gaps = 8/77 (10%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 + + LFD+N G ++ E+ + + G + E + YD+ Sbjct: 3 EEQKQEIKEAFDLFDTNKTGSIDYHELKVAM--------RALGFDVKKPEILELMNEYDR 54 Query: 201 DGNGYIDENELDALLKD 217 +GNGYI ++ ++ + Sbjct: 55 EGNGYIGFDDFLDIMTE 71 Score = 27.1 bits (58), Expect = 8.4, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 20/35 (57%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 + +E +AF+L+D + G ID +EL ++ L Sbjct: 3 EEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALG 37 >2K7B-A nrPDB Length = 76 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 30/74 (40%), Gaps = 8/74 (10%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 EE + +R++D D G+I +L N ++ + + + + + N G Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEM--------ELIELSQQINMNLGG 61 Query: 161 KLELTEMARLLPVQ 174 ++ + L+ + Sbjct: 62 HVDFDDFVELMGPK 75 Score = 42.9 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 26/74 (35%), Gaps = 6/74 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + E + FD D GY+ ++L N ++ + + E+ Q G Sbjct: 8 EIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEM------ELIELSQQINMNLGG 61 Query: 72 KIGIVELAHVLPTE 85 + + ++ + Sbjct: 62 HVDFDDFVELMGPK 75 Score = 33.6 bits (75), Expect = 0.087, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 19/31 (61%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLC 219 +E +AF +D+D +GYI+ +L ++ + Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMG 40 >1KFX-S nrPDB Length = 184 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 32/197 (16%), Positives = 65/197 (32%), Gaps = 41/197 (20%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQEL--QQARKKAGLELSPEMKTFVDQYGQRD 69 QF ++ D + EL N++ ++ + K ++ V Sbjct: 13 EVRQFRRLFAQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDT 71 Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 GK+G E ++ + + + ++++DTD SG I + EL + Sbjct: 72 TGKLGFEEFKYLWNNIKRWQAI---------------YKQFDTDRSGTICSSELPGAFEA 116 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGK 189 N+ + + + Y+D G ++ L + Sbjct: 117 AGFHLNEHLYNMIIRRYSDE---------SGNMDFDNFISCLVRLDA------------- 154 Query: 190 EFNKAFELYDQDGNGYI 206 +AF+ D+DG G I Sbjct: 155 -MFRAFKSLDKDGTGQI 170 Score = 41.0 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 42/126 (33%), Gaps = 16/126 (12%) Query: 96 QLKSCEEFMKTWRKYDT--DHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 + EE + R + + EL N L ++ + D + M+ + Sbjct: 7 EANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAV 66 Query: 154 FDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDA 213 DS+ GKL E + + K + ++ +D D +G I +EL Sbjct: 67 MDSDTTGKLGFEEF--------------KYLWNNIKRWQAIYKQFDTDRSGTICSSELPG 112 Query: 214 LLKDLC 219 + Sbjct: 113 AFEAAG 118 >5I2L-A nrPDB Length = 120 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 40/124 (32%), Gaps = 8/124 (6%) Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 G +G E N F+ K ++ K +++YD GFI+ ELK ++ L Sbjct: 1 GAMGSGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKL 60 Query: 131 LEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKE 190 M+K D + D KL E + L+ Sbjct: 61 GAPQTHLG--------LKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLCVLAR 112 Query: 191 FNKA 194 ++ Sbjct: 113 LSEI 116 Score = 35.2 bits (79), Expect = 0.027, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 +++ +DA G+++ EL+ ++++L + GL K + + + D K+ Sbjct: 32 DMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGL------KNMIKEVDEDFDSKLS 85 Query: 75 IVELAHVLPTEE 86 E + Sbjct: 86 FREFLLIFRKAA 97 Score = 28.3 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 23/55 (41%), Gaps = 4/55 (7%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSD 243 K+ K F+ YD +G+ID EL +++ L + + K + D Sbjct: 31 KDMEKMFKQYDAGRDGFIDLMELKLMMEKLGA---PQTHLG-LKNMIKEVDEDFD 81 >1H4B-A nrPDB Length = 84 Score = 45.2 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 26/67 (38%), Gaps = 9/67 (13%) Query: 102 EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGK 161 E + ++++D + G I EL LK L + + M+ D++ DG Sbjct: 10 ERERIFKRFDANGDGKISAAELGEALKTLG---------SITPDEVKHMMAEIDTDGDGF 60 Query: 162 LELTEMA 168 + E Sbjct: 61 ISFQEFT 67 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 7/70 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ I+ FDA+G G + EL ++ L E+K + + DG Sbjct: 7 DKAERERIFKRFDANGDGKISAAELGEALKTLGS-------ITPDEVKHMMAEIDTDGDG 59 Query: 72 KIGIVELAHV 81 I E Sbjct: 60 FISFQEFTDF 69 Score = 31.0 bits (68), Expect = 0.50, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 21/57 (36%), Gaps = 5/57 (8%) Query: 188 GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 E + F+ +D +G+G I EL LK L + + I DG Sbjct: 8 KAERERIFKRFDANGDGKISAAELGEALKTLGSITPDE-----VKHMMAEIDTDGDG 59 Score = 31.0 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 27/78 (34%), Gaps = 13/78 (16%) Query: 146 YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGY 205 + + K FD+N DGK+ E+ L + E D DG+G+ Sbjct: 10 ERERIFKRFDANGDGKISAAELGEALK---------TLGSITPDEVKHMMAEIDTDGDGF 60 Query: 206 IDENELDALLKDLCEKNK 223 I E D N+ Sbjct: 61 ISFQE----FTDFGRANR 74 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 10/73 (13%) Query: 57 EMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG 116 E + ++ DGKI EL L T + + +E + DTD G Sbjct: 10 ERERIFKRFDANGDGKISAAELGEALKTLGSI----------TPDEVKHMMAEIDTDGDG 59 Query: 117 FIETEELKNFLKD 129 FI +E +F + Sbjct: 60 FISFQEFTDFGRA 72 >3SIA-A nrPDB Length = 220 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 29/80 (36%), Gaps = 8/80 (10%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 L + + D D SG +E EL + + T L M+++FD Sbjct: 46 PLDQYTRIYQWFMGVDRDRSGTLEINEL---MMGQFPGGIRLSPQTAL-----RMMRIFD 97 Query: 156 SNNDGKLELTEMARLLPVQE 175 ++ +G + E + E Sbjct: 98 TDFNGHISFYEFMAMYKFME 117 Score = 30.2 bits (66), Expect = 0.83, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 24/64 (37%), Gaps = 9/64 (14%) Query: 65 YGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 + G + I EL ++ + L S + ++ R +DTD +G I E Sbjct: 60 VDRDRSGTLEINEL--MMGQFPGGIRL-------SPQTALRMMRIFDTDFNGHISFYEFM 110 Query: 125 NFLK 128 K Sbjct: 111 AMYK 114 >1F4Q-A nrPDB Length = 165 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 42/124 (33%), Gaps = 17/124 (13%) Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 G ++ EEL+ L + E +M+ + D ++ GK+ L Sbjct: 12 QDGEVDAEELQRCLTQSGINGTYSPFS---LETCRIMIAMLDRDHTGKMGFNAFKELWAA 68 Query: 174 QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITT 233 + + F DQDG+G ++ +EL + + + + Sbjct: 69 LNAW--------------KENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKR 114 Query: 234 YKKN 237 Y KN Sbjct: 115 YSKN 118 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 21/173 (12%), Positives = 52/173 (30%), Gaps = 30/173 (17%) Query: 27 GSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEE 86 G ++ +ELQ + + + L + + + GK+G + Sbjct: 12 QDGEVDAEELQRCLTQSGINGTYSPFSL-ETCRIMIAMLDRDHTGKMGFNAFKELWAALN 70 Query: 87 NFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY 146 + + + D D SG +E EL+ + + + + Sbjct: 71 AW---------------KENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQT-------- 107 Query: 147 TDLMLKLFDSNNDGKLELTEM----ARLLPVQENFLLKFQGIKMCGKEFNKAF 195 ++K + N G++ + +L + + F + + F Sbjct: 108 LTTIVKRYSKN--GRIFFDDYVACCVKLRALTDFFKKRDHLQQGSADFIYDDF 158 Score = 27.9 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 38/129 (29%), Gaps = 19/129 (14%) Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 DG++ EL L + S E D DH+G + K Sbjct: 13 DGEVDAEELQRCLTQS----GINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA 68 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGK 189 L D + G +E E+ + + + + L Q + K Sbjct: 69 LNA--------------WKENFMTVDQDGSGTVEHHELRQAIGL-MGYRLSPQTLTTIVK 113 Query: 190 EFNKAFELY 198 ++K ++ Sbjct: 114 RYSKNGRIF 122 Score = 27.9 bits (60), Expect = 4.7, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 22/54 (40%), Gaps = 6/54 (11%) Query: 16 FFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 + E ++ D DGSG +E EL+ I + + T V +Y + Sbjct: 72 WKENFMTVDQDGSGTVEHHELRQAIGLMGYRLS------PQTLTTIVKRYSKNG 119 >4OCI-A nrPDB Length = 146 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 22/139 (15%), Positives = 53/139 (38%), Gaps = 20/139 (14%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 K E+ +++ +D D G++ E ++ ++ L + T + ++S Sbjct: 2 QKHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLG-----------VVMETSAIASTYNS 50 Query: 157 NNDGK-LELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 N+ + + + + E A + D+D G+I EL +L Sbjct: 51 NSKVRGMSYELFTSCFS-------QLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRIL 103 Query: 216 KDLCEKNKQDLDINNITTY 234 + + N + +I ++ T+ Sbjct: 104 STIGD-NMEQKEITDLFTF 121 Score = 44.4 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 50/156 (32%), Gaps = 28/156 (17%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 E +L FD DG GYL E ++L++ L + + + + + V Sbjct: 7 DLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSKVRGMS-------- 58 Query: 75 IVELAHVLPTEENFLLLFRCQQLKS--CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 E F F + KS +E D D GFI EL+ L + Sbjct: 59 ----------YELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIG- 107 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMA 168 D + + + G +++ + Sbjct: 108 -------DNMEQKEITDLFTFMGIDEQGVVKVDDFI 136 Score = 27.9 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 7/49 (14%), Positives = 19/49 (38%) Query: 4 SHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGL 52 S L++ + D D G++ EL+ ++ + ++ + Sbjct: 67 SQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEI 115 >1SJJ-A nrPDB Length = 863 Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 14/111 (12%), Positives = 38/111 (34%), Gaps = 15/111 (13%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 +F + HFD +G ++ ++ + + + +A E + G + Sbjct: 726 EFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEA------EFARIMSIVDPNRMGVVT 779 Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKN 125 + E + ++ M +++ D + +I +EL+ Sbjct: 780 FQAFIDFMSRET--------ADTDTADQVMASFKILAGDKN-YITVDELRR 821 >2OPO-A nrPDB Length = 86 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 28/65 (43%), Gaps = 9/65 (13%) Query: 104 MKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLE 163 + ++++DT+ G I + EL + LK L + + M+ D++ DG + Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLG---------SVTPDEVRRMMAEIDTDGDGFIS 64 Query: 164 LTEMA 168 E Sbjct: 65 FDEFT 69 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 24/70 (34%), Gaps = 7/70 (10%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 + I+ FD +G G + EL + ++ L E++ + + DG Sbjct: 9 DIADRERIFKRFDTNGDGKISSSELGDALKTLGS-------VTPDEVRRMMAEIDTDGDG 61 Query: 72 KIGIVELAHV 81 I E Sbjct: 62 FISFDEFTDF 71 Score = 30.6 bits (67), Expect = 0.74, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 9/67 (13%) Query: 148 DLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYID 207 + + K FD+N DGK+ +E+ L + E + D DG+G+I Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALK---------TLGSVTPDEVRRMMAEIDTDGDGFIS 64 Query: 208 ENELDAL 214 +E Sbjct: 65 FDEFTDF 71 Score = 29.0 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 23/56 (41%), Gaps = 5/56 (8%) Query: 189 KEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDG 244 + + F+ +D +G+G I +EL LK L + + + I DG Sbjct: 11 ADRERIFKRFDTNGDGKISSSELGDALKTLG-----SVTPDEVRRMMAEIDTDGDG 61 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 10/81 (12%) Query: 49 KAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWR 108 + + + + ++ DGKI EL L T + + +E + Sbjct: 4 EDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLGSV----------TPDEVRRMMA 53 Query: 109 KYDTDHSGFIETEELKNFLKD 129 + DTD GFI +E +F + Sbjct: 54 EIDTDGDGFISFDEFTDFARA 74 >4I5K-A nrPDB Length = 285 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 38/230 (16%), Positives = 81/230 (35%), Gaps = 30/230 (13%) Query: 43 LQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE-----LAHVLPTEENFLLLFRCQQL 97 L+ A + ++ ++ + GKI E L E + + Sbjct: 50 LKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDY 109 Query: 98 KSCEEFMKTWRKY---DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE--YTDLMLK 152 S E F + K+ DTDH +I +L + N +++ E ++ + + Sbjct: 110 FSYEHFYVIYCKFWELDTDHDLYISQADLSRY--------NDQASSSRIIERIFSGAVTR 161 Query: 153 LFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELD 212 +G++ + + L + K F D DG+G + EL+ Sbjct: 162 GKTIQKEGRMSYADFV--------WFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELE 213 Query: 213 ALLKDLCEKNK----QDLDINNITTYKKNIMALSDGGKLYRTDLALILCA 258 ++ CE+ + + L +++ +++ + GK+ DL A Sbjct: 214 YFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMA 263 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 44/127 (34%), Gaps = 10/127 (7%) Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 +G++ + L +EE ++ +R D D G + EL+ F ++ Sbjct: 168 EGRMSYADFVWFLISEE---------DKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEE 218 Query: 130 LLEKANKT-VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCG 188 E+ ++ + ML L DGK+ L ++ R + F K Sbjct: 219 QCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLD 278 Query: 189 KEFNKAF 195 E F Sbjct: 279 HEQRDPF 285 >1Q80-A nrPDB Length = 174 Score = 42.9 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 24/169 (14%), Positives = 46/169 (27%), Gaps = 23/169 (13%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ- 67 S + + + D D G + + +++ + + + M + + Sbjct: 1 SDLWVQKMKTYFNRIDFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNF 60 Query: 68 ----RDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEE--FMKTWRKYDTDHSGFIETE 121 I + + + + + KS E +R DT+ I + Sbjct: 61 LTAVAGGKGIDETTFINSMKE------MVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRD 114 Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL 170 E F L D+NNDG L L E Sbjct: 115 EYGIFFGMLGLDKT----------MAPASFDAIDTNNDGLLSLEEFVIA 153 >2VRG-A nrPDB Length = 124 Score = 42.9 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 107 WRKYDTDHSGFIETEELK----NFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 ++ +D D + ++ EL + K+ + + + +L D +L+ D NNDG + Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 114 Query: 163 ELTEMARLL 171 + E A+ L Sbjct: 115 DYAEFAKSL 123 Score = 32.1 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 20 WLHFDADGSGYLEGKELQNLIQEL------QQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + D DG+ L+G EL I + +QA + EL + + + +DG I Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 114 Query: 74 GIVELAHVL 82 E A L Sbjct: 115 DYAEFAKSL 123 Score = 31.3 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 35/101 (34%), Gaps = 4/101 (3%) Query: 119 ETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 + ++ ++ L NK + E K+ D + + L+ E++ + Sbjct: 23 TVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEE 82 Query: 179 LKFQGIKMCGKE----FNKAFELYDQDGNGYIDENELDALL 215 Q M E + D++ +GYID E L Sbjct: 83 GSEQAPLMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSL 123 Score = 27.1 bits (58), Expect = 7.6, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 32/83 (38%), Gaps = 8/83 (9%) Query: 170 LLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLD-- 227 ++ E + K + + F+++D DGN +D EL + + ++ + Sbjct: 30 IMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPL 89 Query: 228 ------INNITTYKKNIMALSDG 244 IN I ++ +DG Sbjct: 90 MSEDELINIIDGVLRDDDKNNDG 112 >3BOW-B nrPDB Length = 184 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 45/128 (35%), Gaps = 15/128 (11%) Query: 92 FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 151 + + +F K + + D + EL N L ++ + D + M+ Sbjct: 6 IEANESEEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMV 64 Query: 152 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 + DS+ GKL E + + K++ ++ +D D +G I NEL Sbjct: 65 AVMDSDTTGKLGFEEF--------------KYLWNNIKKWQGIYKRFDTDRSGTIGSNEL 110 Query: 212 DALLKDLC 219 + Sbjct: 111 PGAFEAAG 118 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 31/194 (15%), Positives = 65/194 (33%), Gaps = 41/194 (21%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQEL--QQARKKAGLELSPEMKTFVDQYGQRDDGK 72 QF ++++ D + EL N++ ++ + K ++ V GK Sbjct: 16 QFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGK 74 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 +G E ++ + + + ++++DTD SG I + EL + Sbjct: 75 LGFEEFKYLWNNIKKWQGI---------------YKRFDTDRSGTIGSNELPGAFEAAGF 119 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN 192 N+ + + Y+D G ++ L + Sbjct: 120 HLNQHIYSMIIRRYSDET---------GNMDFDNFISCLVRLDA--------------MF 156 Query: 193 KAFELYDQDGNGYI 206 +AF D++G G I Sbjct: 157 RAFRSLDKNGTGQI 170 >3A4U-B nrPDB Length = 143 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 107 WRKYDTDHSGFIETEELK----NFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 ++ +D D + ++ EL + K+ + + + +L D +L+ D NNDG + Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 133 Query: 163 ELTEMARLL 171 + E A+ L Sbjct: 134 DYAEFAKSL 142 Score = 32.1 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 20 WLHFDADGSGYLEGKELQNLIQEL------QQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + D DG+ L+G EL I + +QA + EL + + + +DG I Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 133 Query: 74 GIVELAHVL 82 E A L Sbjct: 134 DYAEFAKSL 142 Score = 31.3 bits (69), Expect = 0.39, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 35/101 (34%), Gaps = 4/101 (3%) Query: 119 ETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 + ++ ++ L NK + E K+ D + + L+ E++ + Sbjct: 42 TVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEE 101 Query: 179 LKFQGIKMCGKE----FNKAFELYDQDGNGYIDENELDALL 215 Q M E + D++ +GYID E L Sbjct: 102 GSEQAPLMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSL 142 Score = 27.1 bits (58), Expect = 7.8, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 32/83 (38%), Gaps = 8/83 (9%) Query: 170 LLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLD-- 227 ++ E + K + + F+++D DGN +D EL + + ++ + Sbjct: 49 IMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPL 108 Query: 228 ------INNITTYKKNIMALSDG 244 IN I ++ +DG Sbjct: 109 MSEDELINIIDGVLRDDDKNNDG 131 >1SL8-A nrPDB Length = 191 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 53/160 (33%), Gaps = 16/160 (10%) Query: 17 FEIWLHFDADGSGYLEGKELQN-----LIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ D + +G + E+ +I L ++A ++ F G + Sbjct: 19 KHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAK-RHKDAVEAFFGGAGMKYGV 77 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEF--MKTWRKYDTDHSGFIETEELKNFLKD 129 + E + L + + + D D +G I +E K + K Sbjct: 78 ETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTKS 137 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + +E + ++ D + G+L++ EM R Sbjct: 138 AG--------IIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 33.6 bits (75), Expect = 0.082, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 39/94 (41%), Gaps = 17/94 (18%) Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 + +EELK + K+ T + + D + + D + +G + L E Sbjct: 91 LASEELKRYSKN---------QITLIRLWGDALFDIIDKDQNGAISLDEWKA-------- 133 Query: 178 LLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 K GI ++ + F + D D +G +D +E+ Sbjct: 134 YTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEM 167 Score = 27.5 bits (59), Expect = 5.8, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 38/124 (30%), Gaps = 11/124 (8%) Query: 104 MKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG--- 160 + D +H+G I +E+ K N + A+ ++ F G Sbjct: 19 KHMFNFLDVNHNGRISLDEM--VYKASDIVINNLGATPEQAKRHKDAVEAF-FGGAGMKY 75 Query: 161 --KLELTEMARLLPVQENFLLKFQGIKMCGKEFNKA---FELYDQDGNGYIDENELDALL 215 + E E + LK F++ D+D NG I +E A Sbjct: 76 GVETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYT 135 Query: 216 KDLC 219 K Sbjct: 136 KSAG 139 >2M1U-A nrPDB Length = 93 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 30/75 (40%), Gaps = 9/75 (12%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 + ++ + +D D+ GF+ EE + ++D L + + + D Sbjct: 22 SDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPMTEAEITE---------FFEAADP 72 Query: 157 NNDGKLELTEMARLL 171 NN G ++ A +L Sbjct: 73 NNTGFIDYKAFAAML 87 Score = 34.0 bits (76), Expect = 0.067, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 30/79 (37%), Gaps = 10/79 (12%) Query: 4 SHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVD 63 SH+ +Q E + +FD D G++ +E + +I+ E+ F + Sbjct: 19 SHMSDEK---TQLIEAFYNFDGDYDGFVSVEEFRGIIR-------DGLPMTEAEITEFFE 68 Query: 64 QYGQRDDGKIGIVELAHVL 82 + G I A +L Sbjct: 69 AADPNNTGFIDYKAFAAML 87 Score = 30.2 bits (66), Expect = 1.00, Method: Composition-based stats. Identities = 12/82 (14%), Positives = 33/82 (40%), Gaps = 5/82 (6%) Query: 180 KFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIM 239 + + + +AF +D D +G++ E +++D + + IT + + Sbjct: 17 RGSHMSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPMTEAE-----ITEFFEAAD 71 Query: 240 ALSDGGKLYRTDLALILCAGDN 261 + G Y+ A++ ++ Sbjct: 72 PNNTGFIDYKAFAAMLYSVDES 93 Score = 27.1 bits (58), Expect = 7.9, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 31/83 (37%), Gaps = 7/83 (8%) Query: 51 GLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKY 110 G +S E ++ + D G V + E F + R + E + + Sbjct: 18 GSHMSDEKTQLIEAFYNFDGDYDGFVSV-------EEFRGIIRDGLPMTEAEITEFFEAA 70 Query: 111 DTDHSGFIETEELKNFLKDLLEK 133 D +++GFI+ + L + E Sbjct: 71 DPNNTGFIDYKAFAAMLYSVDES 93 >3LCP-C nrPDB Length = 93 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 107 WRKYDTDHSGFIETEELK----NFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 ++ +D D + ++ EL + K+ + + + +L D +L+ D NNDG + Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 83 Query: 163 ELTEMARLL 171 + E A+ L Sbjct: 84 DYAEFAKSL 92 Score = 31.7 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 20 WLHFDADGSGYLEGKELQNLIQEL------QQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + D DG+ L+G EL I + +QA + EL + + + +DG I Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 83 Query: 74 GIVELAHVL 82 E A L Sbjct: 84 DYAEFAKSL 92 Score = 27.1 bits (58), Expect = 7.8, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 29/85 (34%), Gaps = 4/85 (4%) Query: 135 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKE---- 190 NK + E K+ D + + L+ E++ + Q M E Sbjct: 8 NKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINI 67 Query: 191 FNKAFELYDQDGNGYIDENELDALL 215 + D++ +GYID E L Sbjct: 68 IDGVLRDDDKNNDGYIDYAEFAKSL 92 >6EAZ-A nrPDB Length = 379 Score = 42.1 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 40/258 (15%), Positives = 86/258 (33%), Gaps = 37/258 (14%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQ---------------QARKKAGLELSPEM 58 S F + D DG+ +E KE L + + Q ++ + Sbjct: 119 SGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQDGFKTVKTNETEYQDPTVKEPGVNTTL 178 Query: 59 KTFVDQYGQRDDGKIGIVELAHVLP------TEENFLLLFRCQQLKSCEEFMKTWRKYDT 112 + V +G+R + K+ E + E FL + E+F + + Sbjct: 179 Q--VRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEFLQFSKGLNFMRKEDFAEWLLFFTN 236 Query: 113 DHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL-- 170 + I +N + L + ++D+ K + L+ F + + + Sbjct: 237 TENKDIY---WRNVREKLSVGESISLDEFKSFCHFTTHLEDF------AIAMQMFSLAHR 287 Query: 171 ---LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLD 227 L + + G ++ + F+++D DG+ + E +LK+ + Sbjct: 288 PVRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKNRMHRGLWVSQ 347 Query: 228 INNITTYKKNIMALSDGG 245 ++ Y K + S G Sbjct: 348 QQSVQEYWKCVKKESIKG 365 >3AKA-A nrPDB Length = 166 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 17/127 (13%), Positives = 37/127 (29%), Gaps = 8/127 (6%) Query: 100 CEEFMKTWRKYDTDHSGFIETEEL----KNFLKDLLEKANKTVDD---TKLAEYTDLMLK 152 + +D D +G I+ + K L + A + Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAG 62 Query: 153 LFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELD 212 + D + D ++ E V+ + ++ + A + D DG+G + + Sbjct: 63 IADRDGDQRITREEFVTG-AVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTA 121 Query: 213 ALLKDLC 219 L Sbjct: 122 RALTAFG 128 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 22/163 (13%), Positives = 44/163 (26%), Gaps = 21/163 (12%) Query: 20 WLHFDADGSGYLEGKELQNLIQEL--------QQARKKAGLELSPEM-KTFVDQYGQRDD 70 + FD DG+G+++ + + L + R +A + + + + D Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIADRDGD 69 Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 +I E + DTD G + + L Sbjct: 70 QRITREEFVTGAVKRLRDKP--DRFAEIARPFLHAALGVADTDGDGAVTVADTARALTAF 127 Query: 131 LEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 + D++ DGK+ TE+ Sbjct: 128 G----------VPEDLARQAAAALDTDGDGKVGETEIVPAFAR 160 >3TZ1-A nrPDB Length = 74 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 32/76 (42%), Gaps = 8/76 (10%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 E + +R D + G I+ + L+ LK L ++ + + + M+ D++ Sbjct: 6 ERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTE--------DEIENMIAETDTDGS 57 Query: 160 GKLELTEMARLLPVQE 175 G ++ E L+ + Sbjct: 58 GTVDYEEFKCLMMSSD 73 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 8/74 (10%), Positives = 26/74 (35%), Gaps = 6/74 (8%) Query: 9 SLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQR 68 + + E + D + G ++ L+ +++ L + E++ + + Sbjct: 2 EDLDERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTED------EIENMIAETDTD 55 Query: 69 DDGKIGIVELAHVL 82 G + E ++ Sbjct: 56 GSGTVDYEEFKCLM 69 >5VT9-A nrPDB Length = 152 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 22/171 (12%), Positives = 58/171 (33%), Gaps = 29/171 (16%) Query: 2 AESHLQSSLITASQFFEIWLHFDADGSG-YLEGKELQNLIQELQQARKKAGLELSPEMKT 60 A+ +Q +L + E++ F+A SG + + L ++L A A + Sbjct: 5 ADEDMQEALEEMVEADEMYARFNARASGGKVSTGDAMILARQLGLAPSYADKQ------- 57 Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 + ++ + + T + + E+ ++ + +D G++ Sbjct: 58 ---AFEEKSGDNLDYASFQKFVGTSTH--------PEDNIEDLVEAFAYFDVSKHGYLTR 106 Query: 121 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +++ N L E + AEY +++ + + + Sbjct: 107 KQMGNILMTYGEPLTTEEFNALAAEYFT----------SDQIDYRQFCKAM 147 Score = 31.0 bits (68), Expect = 0.52, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 21/51 (41%) Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQD 225 + F+ + ++ +AF +D +GY+ ++ +L E + Sbjct: 73 QKFVGTSTHPEDNIEDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTTE 123 >5VE9-A nrPDB Length = 91 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 26/82 (31%), Gaps = 12/82 (14%) Query: 91 LFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL-KNFLKDLLEKANKTVDDTKLAEYTDL 149 + KS M +R+ D D G I +E L + Sbjct: 19 MRWMNHKKSR--VMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMT---------A 67 Query: 150 MLKLFDSNNDGKLELTEMARLL 171 + +FD + DG ++ E L Sbjct: 68 VADIFDRDGDGYIDYYEFVAAL 89 Score = 34.8 bits (78), Expect = 0.038, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 8/61 (13%) Query: 150 MLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDEN 209 + D + DGK+ E + + K + + ++D+DG+GYID Sbjct: 32 FFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVAD--------IFDRDGDGYIDYY 83 Query: 210 E 210 E Sbjct: 84 E 84 Score = 34.8 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 24/69 (34%), Gaps = 6/69 (8%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 S+ + + D D G + +E + I + K EM D + + DG I Sbjct: 27 SRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKL------EMTAVADIFDRDGDGYI 80 Query: 74 GIVELAHVL 82 E L Sbjct: 81 DYYEFVAAL 89 Score = 28.3 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 19/64 (29%), Gaps = 9/64 (14%) Query: 60 TFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIE 119 F + + DGKI E + + + +D D G+I+ Sbjct: 31 DFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVAD---------IFDRDGDGYID 81 Query: 120 TEEL 123 E Sbjct: 82 YYEF 85 >2FCE-A nrPDB Length = 70 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 35/78 (44%), Gaps = 8/78 (10%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 E+F+K ++ +D + +G + +L+ L L EK D +LK + Sbjct: 1 KAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDA--------EVDELLKGVEV 52 Query: 157 NNDGKLELTEMARLLPVQ 174 +++G+++ + + Q Sbjct: 53 DSNGEIDYKKFIEDVLRQ 70 Score = 32.9 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 10/71 (14%), Positives = 27/71 (38%), Gaps = 6/71 (8%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIG 74 F + + FD + +G + +L+ ++ L + A E+ + +G+I Sbjct: 6 DFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDA------EVDELLKGVEVDSNGEID 59 Query: 75 IVELAHVLPTE 85 + + + Sbjct: 60 YKKFIEDVLRQ 70 Score = 31.7 bits (70), Expect = 0.31, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 22/37 (59%) Query: 185 KMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEK 221 K ++F KAF+++D++ G + +L +L L EK Sbjct: 1 KAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEK 37 >5E1J-A nrPDB Length = 741 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 37/124 (29%), Gaps = 17/124 (13%) Query: 75 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKA 134 L + + + + + K + D+D +G I+ + + L Sbjct: 305 YDSFKEQLAKQVSGMDQMKRRM------LEKAFGLIDSDKNGEIDKNQCIKLFEQL---T 355 Query: 135 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKA 194 N E L+ D D K+ E A L + ++ +E Sbjct: 356 NYRTLPKISKEEFGLIFDELDDTRDFKINKDEFA--------DLCQAIALRFQKEEVPSL 407 Query: 195 FELY 198 FE + Sbjct: 408 FEHF 411 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 31/91 (34%), Gaps = 7/91 (7%) Query: 164 LTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDL-CEKN 222 L Q + +M + KAF L D D NG ID+N+ L + L + Sbjct: 305 YDSFKEQLAKQVSG-----MDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRT 359 Query: 223 KQDLDINNITTYKKNIMALSDGGKLYRTDLA 253 + + D K+ + + A Sbjct: 360 LPKISKEEFGLIFDELDDTRD-FKINKDEFA 389 >4YGB-B nrPDB Length = 104 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 37/84 (44%), Gaps = 4/84 (4%) Query: 92 FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK----NFLKDLLEKANKTVDDTKLAEYT 147 ++ E + ++ +D D + ++ EL + K+ + + + +L Sbjct: 20 RHMLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 79 Query: 148 DLMLKLFDSNNDGKLELTEMARLL 171 D +L+ D NNDG ++ E A+ L Sbjct: 80 DGVLRDDDKNNDGYIDYAEFAKSL 103 Score = 31.0 bits (68), Expect = 0.56, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 20 WLHFDADGSGYLEGKELQNLIQEL------QQARKKAGLELSPEMKTFVDQYGQRDDGKI 73 + D DG+ L+G EL I + +QA + EL + + + +DG I Sbjct: 35 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 94 Query: 74 GIVELAHVL 82 E A L Sbjct: 95 DYAEFAKSL 103 >1NP8-A nrPDB Length = 159 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 45/128 (35%), Gaps = 15/128 (11%) Query: 92 FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 151 + + +F K + + D + EL N L ++ + D + M+ Sbjct: 2 IEANESEEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMV 60 Query: 152 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 + DS+ GKL E + + K++ ++ +D D +G I NEL Sbjct: 61 AVMDSDTTGKLGFEEF--------------KYLWNNIKKWQGIYKRFDTDRSGTIGSNEL 106 Query: 212 DALLKDLC 219 + Sbjct: 107 PGAFEAAG 114 Score = 35.2 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 55/159 (34%), Gaps = 27/159 (16%) Query: 15 QFFEIWLHFDADGSGYLEGKELQNLIQEL--QQARKKAGLELSPEMKTFVDQYGQRDDGK 72 QF ++++ D + EL N++ ++ + K ++ V GK Sbjct: 12 QFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGK 70 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 +G E ++ + + + ++++DTD SG I + EL + Sbjct: 71 LGFEEFKYLWNNIKKWQGI---------------YKRFDTDRSGTIGSNELPGAFEAAGF 115 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 N+ + + Y+D G ++ L Sbjct: 116 HLNQHIYSMIIRRYSDET---------GNMDFDNFISCL 145 >1UHK-A nrPDB Length = 191 Score = 40.6 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 23/160 (14%), Positives = 51/160 (31%), Gaps = 16/160 (10%) Query: 17 FEIWLHFDADGSGYLEGKELQN-----LIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ D + +G + E+ +I L ++A ++ F G + Sbjct: 19 KHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAK-RHKDAVEAFFGGAGMKYGV 77 Query: 72 KIGIVELAHVLPTEENFLLLFRCQQLKSCEEF--MKTWRKYDTDHSGFIETEELKNFLKD 129 + L + + + D D +G I +E K + K Sbjct: 78 ETDWPAYIEGWKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKA 137 Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + +E + ++ D + G+L++ EM R Sbjct: 138 AG--------IIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 34.4 bits (77), Expect = 0.046, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 39/95 (41%), Gaps = 17/95 (17%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 + T+EL+ + K+ + T + + D + + D + +G + L E Sbjct: 90 KLATDELEKYAKN---------EPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKA--- 137 Query: 177 FLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 GI ++ + F + D D +G +D +E+ Sbjct: 138 -----AGIIQSSEDCEETFRVCDIDESGQLDVDEM 167 >5W1A-B nrPDB Length = 155 Score = 40.6 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 25/153 (16%), Positives = 62/153 (40%), Gaps = 20/153 (13%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 ++ + G G ++ +L + ++ L A +E K +R++ KI + E Sbjct: 15 VFEVMGSPGEG-IDAVDLGDALRALNLNPTLALIEKLGGTK-------KRNEKKIKLDEF 66 Query: 79 AHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV 138 + + + ++ E+F++ + YD + +G + EL++ L L E + Sbjct: 67 LPIYSQ------VKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQ 120 Query: 139 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 +T A+ D +++G + + + Sbjct: 121 VETLFADCMDP------EDDEGFIPYSPFLARM 147 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 58/167 (34%), Gaps = 20/167 (11%) Query: 92 FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLML 151 + E + + G I+ +L + L+ L + + Sbjct: 1 MADVPKREVENVEFVFEVMGSPGEG-IDAVDLGDALRALNLNPTLALIEKLGGTK----- 54 Query: 152 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 N+ K++L E + +K + + C ++F + +LYD++ NG + EL Sbjct: 55 ----KRNEKKIKLDEFLPIYS-----QVKKEKEQGCYEDFIECLKLYDKEENGTMLLAEL 105 Query: 212 DALLKDLCEKNKQDLDINNITT-YKKNIMALSDGGKLYRTDLALILC 257 L L E LD + T + + D G + + +C Sbjct: 106 QHALLALGE----SLDDEQVETLFADCMDPEDDEGFIPYSPFLARMC 148 >1S6J-A nrPDB Length = 87 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 33/80 (41%), Gaps = 11/80 (13%) Query: 94 CQQLKSCEE---FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLM 150 + S EE + ++ DTD+SG I +ELK+ LK + + ++ + Sbjct: 13 MAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMES--------EIKDL 64 Query: 151 LKLFDSNNDGKLELTEMARL 170 + D + G ++ E Sbjct: 65 MDAADIDKSGTIDYGEFIAA 84 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 25/70 (35%), Gaps = 6/70 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 E++ D D SG + EL++ ++ + ++ E+K +D G Sbjct: 21 EIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMES------EIKDLMDAADIDKSG 74 Query: 72 KIGIVELAHV 81 I E Sbjct: 75 TIDYGEFIAA 84 >4L9M-A nrPDB Length = 559 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 28/84 (33%), Gaps = 17/84 (20%) Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEF 191 K + + D + K +D + DG + E ++ F Sbjct: 412 PKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAA-----------------SF 454 Query: 192 NKAFELYDQDGNGYIDENELDALL 215 +F + D+D G I +E+ A Sbjct: 455 PFSFCVMDKDREGLISRDEITAYF 478 Score = 32.1 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 23/93 (24%), Gaps = 21/93 (22%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 ++ YD D G+I EE + + D + +G + E Sbjct: 431 FKNYDHDQDGYISQEEFEKIAASF-----------------PFSFCVMDKDREGLISRDE 473 Query: 167 ----MARLLPVQENFLLKFQGIKMCGKEFNKAF 195 R + L F F Sbjct: 474 ITAYFMRASSIYSKLGLGFPHNFQETTYLKPTF 506 >2LVV-A nrPDB Length = 226 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 50/154 (32%), Gaps = 20/154 (12%) Query: 18 EIWLHFDADGSGYLEGKEL---QNLIQELQQARKKAGLELSPEMKTFVDQYGQ-RDDGKI 73 E++ FD +G+G L +E+ I +L + + D + + G+ Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEE 114 Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 +VE L C E + D D S +E +E K L L E Sbjct: 115 DLVEFLEF--------RLMLCYIYDIF-ELTVMFDTMDKDGSLLLELQEFKEALPKLKEW 165 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 D T + D+N G + E Sbjct: 166 GVDITDAT-------TVFNEIDTNGSGVVTFDEF 192 Score = 35.2 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 64/182 (35%), Gaps = 25/182 (13%) Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 GK G + E + R + +S ++ ++++DT+ +G + E+ L Sbjct: 21 GKDGKTTADRKVAWERIRCAIPRDKDAESKSRRIELFKQFDTNGTGKLGFREV------L 74 Query: 131 LEKANKTVDDTKLAEYTDLMLKLFDSNND--------GKLELTEMARLLPVQENFLLKFQ 182 D D++ + FD D G+ +L E +L + Sbjct: 75 DGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEEDLVEFLEF-----RLMLCYI 129 Query: 183 GIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALS 242 E F+ D+DG+ + EL + L + + +DI + TT I Sbjct: 130 YDIF---ELTVMFDTMDKDGSLLL---ELQEFKEALPKLKEWGVDITDATTVFNEIDTNG 183 Query: 243 DG 244 G Sbjct: 184 SG 185 >6IIE-A nrPDB Length = 93 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 35/82 (42%), Gaps = 1/82 (1%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEEL-KNFLKDLLEKANKTVDDTKLAEYTDLMLK 152 + + ++ T++ YDTD +G +++ E+ K L+ + D ++L M+K Sbjct: 2 MEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 153 LFDSNNDGKLELTEMARLLPVQ 174 D + G + E R Sbjct: 62 EIDYDGSGSVSQAEWVRAGATT 83 Score = 33.3 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 188 GKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQ-DLDINNITTYKKNIMALSD 243 + F+LYD D NG +D +E+D ++ + + D D++ + + +M D Sbjct: 8 EDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEID 64 Score = 32.1 bits (71), Expect = 0.27, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 31/79 (39%), Gaps = 3/79 (3%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAG---LELSPEMKTFVDQYGQRDDGKIGIV 76 + +D D +G L+ E+ +I ++ + + EL P ++ + + G + Sbjct: 15 FKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQA 74 Query: 77 ELAHVLPTEENFLLLFRCQ 95 E T L+L + Sbjct: 75 EWVRAGATTVPLLVLLGLE 93 >4P5W-A nrPDB Length = 411 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 22/165 (13%), Positives = 45/165 (27%), Gaps = 28/165 (16%) Query: 55 SPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDH 114 ++ Q DG I E L FM ++ +D Sbjct: 77 PKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDAL-----------FMVAFQLFDKAG 125 Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 G + E++K + + +E+ L F L E + L Sbjct: 126 KGEVTFEDVKQVFGQTTIH--QHIPFNWDSEFVQL---HFGKERKRHLTYAEFTQFL--- 177 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 219 +++ + +AF D G + + ++ + Sbjct: 178 ---------LEIQLEHAKQAFVQRDNARTGRVTAIDFRDIMVTIR 213 Score = 35.6 bits (80), Expect = 0.020, Method: Composition-based stats. Identities = 16/140 (11%), Positives = 41/140 (29%), Gaps = 16/140 (11%) Query: 76 VELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKAN 135 +E + L + + + + F+ + ++ ++ Sbjct: 15 IEGRTATSEAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQ 74 Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAF 195 + +L+ + D DG + E V + F AF Sbjct: 75 PN------PKTVELLSGVVDQTKDGLISFQEFVAFESV----------LCAPDALFMVAF 118 Query: 196 ELYDQDGNGYIDENELDALL 215 +L+D+ G G + ++ + Sbjct: 119 QLFDKAGKGEVTFEDVKQVF 138 Score = 35.6 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 15/131 (11%), Positives = 42/131 (32%), Gaps = 19/131 (14%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 ES L + + F + FD G G + ++++ + Q + + + + Sbjct: 104 ESVLCAPD---ALFMVAFQLFDKAGKGEVTFEDVKQV---FGQTTIHQHIPFNWDSEFVQ 157 Query: 63 DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEE 122 +G+ + E L + E + + + D +G + + Sbjct: 158 LHFGKERKRHLTYAEFTQFLLEIQL-------------EHAKQAFVQRDNARTGRVTAID 204 Query: 123 LKNFLKDLLEK 133 ++ + + Sbjct: 205 FRDIMVTIRPH 215 >4I5L-B nrPDB Length = 413 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 36/227 (15%), Positives = 77/227 (33%), Gaps = 30/227 (13%) Query: 43 LQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE-----LAHVLPTEENFLLLFRCQQL 97 L++A + ++ ++ + G+I E + E + + + Sbjct: 132 LKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEF 191 Query: 98 KSCEEFMKTWRKY---DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE--YTDLMLK 152 S E F + K+ DTDH I+ ++L N TK+ + ++ + + Sbjct: 192 FSYEHFYVIYCKFWELDTDHDLLIDADDLAR--------HNDHALSTKMIDRIFSGAVTR 243 Query: 153 LFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELD 212 +GK+ + + L + K F D DG+G + EL+ Sbjct: 244 GRKVQKEGKISYADFV--------WFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELE 295 Query: 213 ALLKDLCEK----NKQDLDINNITTYKKNIMALSDGGKLYRTDLALI 255 ++ C + + L + +++ GK+ DL Sbjct: 296 YFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRC 342 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 28/135 (20%), Positives = 47/135 (34%), Gaps = 10/135 (7%) Query: 70 DGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129 +GKI + L +EE K+ +R D D G + EL+ F ++ Sbjct: 250 EGKISYADFVWFLISEE---------DKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEE 300 Query: 130 LLEKANKT-VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCG 188 + + ++ + ML L +GK+ L ++ R F F K Sbjct: 301 QCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLD 360 Query: 189 KEFNKAFELYDQDGN 203 E + L GN Sbjct: 361 HEQKEQISLLRSTGN 375 >6AGH-A nrPDB Length = 339 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 34/228 (14%), Positives = 76/228 (33%), Gaps = 33/228 (14%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSP-------------EMKT 60 S F + D DG+ +E +E L + + + ++ + Sbjct: 116 SGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQDDLMTVKTNETGYQEAIVKEPEINTTL 175 Query: 61 FVDQYGQRDDGKIGIVELAHVLP------TEENFLLLFRCQQLKSCEEFMKTWRKYDTDH 114 + +G+R K+ E + E FL + E+F + + Sbjct: 176 QMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEFLQFSKGLSFMRKEDFAEWLLFFTNTE 235 Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARL---- 170 + I KN + L + ++D+ K + L+ F + + + Sbjct: 236 NKDIY---WKNVREKLSAGESISLDEFKSFCHFTTHLEDF------AIAMQMFSLAHRPV 286 Query: 171 -LPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKD 217 L + + G ++ + F+++D DG+ + E +LK+ Sbjct: 287 RLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKN 334 Score = 36.0 bits (81), Expect = 0.019, Method: Composition-based stats. Identities = 25/196 (12%), Positives = 64/196 (32%), Gaps = 13/196 (6%) Query: 5 HLQSSLITASQFFEIWLHFDADGSGYLEGKE-LQNLIQELQQARKKAGLELSPEMKTFVD 63 ++ + +F + + + +G Y+ ++ L +++ E + + +++ + Sbjct: 20 YIGKPSLRKQRFMQ-FSSLEHEGEYYMTPRDFLFSVMFEQMERKTSVKKLTKKDIEDTLS 78 Query: 64 QYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL 123 G +L L K F ++ DTD + IE E Sbjct: 79 GIQTAGCGSTFFRDLGDKGLISYTEYLFLLTILTKPHSGFHVAFKMLDTDGNEMIEKREF 138 Query: 124 KNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN-----------NDGKLELTEMARLLP 172 K + ++ + T Y + ++K + N KL E R + Sbjct: 139 FKLQKIISKQDDLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFME 198 Query: 173 VQENFLLKFQGIKMCG 188 + + + + ++ Sbjct: 199 NLQTEIQEMEFLQFSK 214 >4MSP-A nrPDB Length = 200 Score = 38.7 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 37/87 (42%) Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 141 +P E + ++++ +++++ D + + +E+K +LK EK V+++ Sbjct: 108 IPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNES 167 Query: 142 KLAEYTDLMLKLFDSNNDGKLELTEMA 168 + + D + DG + E Sbjct: 168 HHDALVEDIFDKEDEDKDGFISAREFT 194 Score = 31.3 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 21/60 (35%) Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 + D N+D KL E+ L + F+ D+D +G+I E Sbjct: 133 FQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISARE 192 >4NQG-A nrPDB Length = 197 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 61/158 (38%), Gaps = 14/158 (8%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTW-----RKYDTD 113 K + +G+I + E+ H L +Q + ++ ++ + +YD D Sbjct: 24 KHMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFFGGAGLEYDKD 83 Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 + E K K LE+ +K T + + D + + D + +G + L E + Sbjct: 84 TTWPEYIEGWKRLAKTELERHSKN-RVTLIRLWGDALFDIIDKDGNGSVSLDEWIQ---- 138 Query: 174 QENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 GI+ + F D DG+G +D +E+ Sbjct: 139 ----YTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEM 172 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 23/164 (14%), Positives = 53/164 (32%), Gaps = 16/164 (9%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQN-----LIQELQQARKKAGLELSPEMKTFVDQYGQ 67 ++ ++ D + +G + E+ + + ++L A ++ ++ F G Sbjct: 20 IARHKHMFNFLDINSNGQINLNEMVHKASNIICKKLG-ATEEQTRRHQKCVEDFFGGAGL 78 Query: 68 RDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEF--MKTWRKYDTDHSGFIETEELKN 125 D E L + + + D D +G + +E Sbjct: 79 EYDKDTTWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQ 138 Query: 126 FLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 + + ++ + A D + DGKL++ EM R Sbjct: 139 YTHCAGIQQSRGQCEATFAHC--------DLDGDGKLDVDEMTR 174 >4MEW-A nrPDB Length = 356 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 36/227 (15%), Positives = 77/227 (33%), Gaps = 30/227 (13%) Query: 43 LQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE-----LAHVLPTEENFLLLFRCQQL 97 L++A + ++ ++ + G+I E + E + + + Sbjct: 124 LKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEF 183 Query: 98 KSCEEFMKTWRKY---DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE--YTDLMLK 152 S E F + K+ DTDH I+ ++L N TK+ + ++ + + Sbjct: 184 FSYEHFYVIYCKFWELDTDHDLLIDADDLAR--------HNDHALSTKMIDRIFSGAVTR 235 Query: 153 LFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELD 212 +GK+ + + L + K F D DG+G + EL+ Sbjct: 236 GRKVQKEGKISYADFV--------WFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELE 287 Query: 213 ALLKDLCEK----NKQDLDINNITTYKKNIMALSDGGKLYRTDLALI 255 ++ C + + L + +++ GK+ DL Sbjct: 288 YFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRC 334 >3A8R-A nrPDB Length = 179 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 34/92 (36%) Query: 80 HVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD 139 VL +E + + D + G + EE+K + + Sbjct: 77 QVLTKDELKDFYEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKI 136 Query: 140 DTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + EYT L+++ D N G +E+ ++ LL Sbjct: 137 KERADEYTALIMEELDPTNLGYIEMEDLEALL 168 Score = 34.8 bits (78), Expect = 0.043, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 38/98 (38%), Gaps = 8/98 (8%) Query: 118 IETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENF 177 + +ELK+F + L D + D N DG+L E+ ++ + + Sbjct: 79 LTKDELKDFYEQL--------TDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIALSASA 130 Query: 178 LLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALL 215 + + + E D GYI+ +L+ALL Sbjct: 131 NKLSKIKERADEYTALIMEELDPTNLGYIEMEDLEALL 168 >1NSH-A nrPDB Length = 101 Score = 37.1 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 1/71 (1%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E + ++KY G T FL + + + K D M+K D N+DG Sbjct: 11 ESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDG 69 Query: 161 KLELTEMARLL 171 +L+ E L+ Sbjct: 70 QLDFQEFLNLI 80 >1TIZ-A nrPDB Length = 67 Score = 37.1 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 9/65 (13%), Positives = 20/65 (30%), Gaps = 8/65 (12%) Query: 104 MKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLE 163 + + K+D + G + +E + E + D + +G+L Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFT--------QEDIVKFFEEIDVDGNGELN 55 Query: 164 LTEMA 168 E Sbjct: 56 ADEFT 60 Score = 34.8 bits (78), Expect = 0.037, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 8/72 (11%) Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 + + FD N DGKL L E + + ++ K FE D DGNG + Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYF--------TQEDIVKFFEEIDVDGNGEL 54 Query: 207 DENELDALLKDL 218 + +E + ++ + Sbjct: 55 NADEFTSCIEKM 66 Score = 27.9 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 8/68 (11%), Positives = 21/68 (30%), Gaps = 6/68 (8%) Query: 17 FEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIV 76 ++ FD + G L E + + ++ F ++ +G++ Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFT------QEDIVKFFEEIDVDGNGELNAD 57 Query: 77 ELAHVLPT 84 E + Sbjct: 58 EFTSCIEK 65 >4NSC-A nrPDB Length = 401 Score = 37.1 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 18/127 (14%), Positives = 47/127 (37%), Gaps = 6/127 (4%) Query: 31 LEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLL 90 ++ K+L + ++L++ K+ E++ F +D + H+ + + Sbjct: 262 VQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVDT-ALSFYHMAGASLDKVT 320 Query: 91 LFRCQQLKSCEEFMK-----TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAE 145 + + + + E + +D D +G + +E + +K L + + D Sbjct: 321 MQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDMGFTR 380 Query: 146 YTDLMLK 152 M K Sbjct: 381 LMQAMWK 387 Score = 31.0 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 109 KYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMA 168 K+ + S F E + T + ++ K+FD N DG++++ E Sbjct: 112 KFADEGSIFYTLGECGLI--SFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFE 169 Query: 169 RLLPV 173 ++ + Sbjct: 170 QVQSI 174 Score = 30.2 bits (66), Expect = 0.86, Method: Composition-based stats. Identities = 35/230 (15%), Positives = 69/230 (30%), Gaps = 43/230 (18%) Query: 16 FFEIWLHFDADGSGYLEGKEL---------QNLIQELQQARKKAGLELSPEMKTFVDQY- 65 F + FD +G G ++ +E Q + + R G L + + + Y Sbjct: 148 FEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYF 207 Query: 66 -GQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELK 124 G GK+ I ++ +L ++ G I + Sbjct: 208 FGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPV--------------DGRITERQFG 253 Query: 125 NFL------KDLLEKANKTVDDTKLAEYTDLMLKLFDS---------NNDGKLELTEMAR 169 L + A + E L + ++ + D L MA Sbjct: 254 GMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAG 313 Query: 170 LLPVQ---ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLK 216 + + +++ + F L+D DGNG + E +++K Sbjct: 314 ASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMK 363 Score = 29.8 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 59/192 (30%), Gaps = 28/192 (14%) Query: 22 HFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHV 81 F AD G L K ++LQ K E + DG+I + + Sbjct: 207 FFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPV-----------DGRITERQFGGM 255 Query: 82 L----PTEENFLLLFRCQQLKSCEEFM-------KTWRKYDTDHSGFIETEELKNFLKDL 130 L + L + Q K +E + + + + + + Sbjct: 256 LLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGAS 315 Query: 131 LEKANKTVDDTKLAEYT------DLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGI 184 L+K +A+ D++ LFD + +G+L E ++ + L+ Sbjct: 316 LDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKD 375 Query: 185 KMCGKEFNKAFE 196 + ++ Sbjct: 376 MGFTRLMQAMWK 387 Score = 27.5 bits (59), Expect = 6.3, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 23/48 (47%) Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKN 222 +++ + + F AF+++D +G+G +D E + + + + Sbjct: 132 SDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQT 179 Score = 27.1 bits (58), Expect = 8.3, Method: Composition-based stats. Identities = 8/24 (33%), Positives = 16/24 (66%) Query: 19 IWLHFDADGSGYLEGKELQNLIQE 42 ++ FD DG+G L KE +++++ Sbjct: 341 VFALFDCDGNGELSNKEFVSIMKQ 364 >5XOP-A nrPDB Length = 66 Score = 37.1 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 27/63 (42%), Gaps = 8/63 (12%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 +++ D + G + EE+K F+ K + L+ K D + DG ++ E Sbjct: 6 FKEIDVNGDGAVSYEEVKAFV--------SKKRAIKNEQLLQLIFKSIDKDGDGFIDFEE 57 Query: 167 MAR 169 A+ Sbjct: 58 FAK 60 Score = 36.0 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 8/72 (11%) Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 + + K D N DG + E+ + + + F+ D+DG+G+I Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIK--------NEQLLQLIFKSIDKDGDGFI 53 Query: 207 DENELDALLKDL 218 D E + Sbjct: 54 DFEEFAKFYGSI 65 Score = 36.0 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 26/72 (36%), Gaps = 9/72 (12%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 + + DG + E+ + + + +K+ + ++ D D GFI Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKK---------RAIKNEQLLQLIFKSIDKDGDGFI 53 Query: 119 ETEELKNFLKDL 130 + EE F + Sbjct: 54 DFEEFAKFYGSI 65 Score = 30.2 bits (66), Expect = 0.92, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 24/64 (37%), Gaps = 6/64 (9%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE 77 ++ D +G G + +E++ + KK ++ ++ + DG I E Sbjct: 4 ALFKEIDVNGDGAVSYEEVKAFVS------KKRAIKNEQLLQLIFKSIDKDGDGFIDFEE 57 Query: 78 LAHV 81 A Sbjct: 58 FAKF 61 >2G2B-A nrPDB Length = 150 Score = 36.7 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 35/93 (37%), Gaps = 7/93 (7%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 F E ++ FD +G+G ++ L+ ++++L + E+K + + Sbjct: 50 LEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLG------VPKTHLELKKLIGEVSSGSGET 103 Query: 73 IGIVELAHVL-PTEENFLLLFRCQQLKSCEEFM 104 + ++ L + + K+ E+ Sbjct: 104 FSYPDFLRMMLGKRSAILKMILMYEEKAREKEK 136 Score = 30.2 bits (66), Expect = 0.84, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 35/93 (37%), Gaps = 10/93 (10%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E F + + ++D + +G I+ LK L+ L ++ S + Sbjct: 51 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL--------ELKKLIGEVSSGSGE 102 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNK 193 + R++ + + +LK I M ++ + Sbjct: 103 TFSYPDFLRMMLGKRSAILK--MILMYEEKARE 133 >1ZFS-A nrPDB Length = 93 Score = 36.3 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 + +ELK+ L+ + + +D K A+ D ++K D N DG+++ E L+ Sbjct: 27 KLSKKELKDLLQT---ELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAA 80 >2M7M-A nrPDB Length = 66 Score = 36.3 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 26/72 (36%), Gaps = 8/72 (11%) Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYI 206 + + K D N DG + E+ + + + F+ D DGNG I Sbjct: 2 AEALFKEIDVNGDGAVSYEEVKAFVSKKRAIK--------NEQLLQLIFKSIDADGNGEI 53 Query: 207 DENELDALLKDL 218 D+NE + Sbjct: 54 DQNEFAKFYGSI 65 Score = 32.9 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 29/63 (46%), Gaps = 8/63 (12%) Query: 107 WRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTE 166 +++ D + G + EE+K F+ K + L+ K D++ +G+++ E Sbjct: 6 FKEIDVNGDGAVSYEEVKAFV--------SKKRAIKNEQLLQLIFKSIDADGNGEIDQNE 57 Query: 167 MAR 169 A+ Sbjct: 58 FAK 60 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 10/72 (13%), Positives = 25/72 (34%), Gaps = 9/72 (12%) Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 + + DG + E+ + + + +K+ + ++ D D +G I Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKK---------RAIKNEQLLQLIFKSIDADGNGEI 53 Query: 119 ETEELKNFLKDL 130 + E F + Sbjct: 54 DQNEFAKFYGSI 65 Score = 27.9 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 24/64 (37%), Gaps = 6/64 (9%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVE 77 ++ D +G G + +E++ + KK ++ ++ +G+I E Sbjct: 4 ALFKEIDVNGDGAVSYEEVKAFVS------KKRAIKNEQLLQLIFKSIDADGNGEIDQNE 57 Query: 78 LAHV 81 A Sbjct: 58 FAKF 61 >2SAS-A nrPDB Length = 185 Score = 36.3 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 38/126 (30%), Gaps = 9/126 (7%) Query: 101 EEFMKTWRKY-DTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL------ 153 ++ T+ + D +H G I+ + ++ + E ++ D + Sbjct: 8 QKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDLKG 67 Query: 154 -FDSNNDGKLELTEMARLLPVQ-ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 211 D N D + E + C F+ D G+G +D E Sbjct: 68 RADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDGIVDLEEF 127 Query: 212 DALLKD 217 K+ Sbjct: 128 QNYCKN 133 Score = 31.7 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 34/109 (31%), Gaps = 7/109 (6%) Query: 66 GQRDDGKIGIVELAHVLPT-EENFLLLFRCQQLKS-----CEEFMKTWRKYDTDHSGFIE 119 DG I + ++ +E KS +E+ + D + + Sbjct: 19 DMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDLKGRADINKDDVVS 78 Query: 120 TEE-LKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 EE L + K + + + K D + DG ++L E Sbjct: 79 WEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDGIVDLEEF 127 Score = 31.0 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 14/132 (10%), Positives = 38/132 (28%), Gaps = 10/132 (7%) Query: 9 SLITASQFFEIWLHF-DADGSGYLEGKELQNLIQELQQ---------ARKKAGLELSPEM 58 + + + F D + G ++ + ++++ ++ K L E Sbjct: 3 NDFQKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEW 62 Query: 59 KTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFI 118 + + D + E + ++ D G + Sbjct: 63 RDLKGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDGIV 122 Query: 119 ETEELKNFLKDL 130 + EE +N+ K+ Sbjct: 123 DLEEFQNYCKNF 134 >2LUC-A nrPDB Length = 105 Score = 36.0 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 1/71 (1%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E + ++KY G+ T FL + + + K D M+K D+N+DG Sbjct: 15 ESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDG 73 Query: 161 KLELTEMARLL 171 +L+ +E L+ Sbjct: 74 QLDFSEFLNLI 84 >6D1W-A nrPDB Length = 740 Score = 36.0 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 11/79 (13%) Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 + GKL E+ + +G E F YDQDG+ + E+E Sbjct: 673 ISESLRQGGGKLNFDELRQ----------DLKGKGHTDAEIEAIFTKYDQDGDQELTEHE 722 Query: 211 LDALLKDLCEKNKQDLDIN 229 + DL EK ++DLD++ Sbjct: 723 HQQMRDDL-EKEREDLDLD 740 >1BOD-A nrPDB Length = 74 Score = 36.0 bits (81), Expect = 0.016, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 KS EE + KYD + G + EELK L+ K + D + + D N Sbjct: 2 KSPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMST------LDELFEELDKN 55 Query: 158 NDGKLELTEMARLLPV 173 DG++ E L+ Sbjct: 56 GDGEVSFEEFQVLVKK 71 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 10/75 (13%), Positives = 30/75 (40%), Gaps = 4/75 (5%) Query: 10 LITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRD 69 + + + I+ +D +G G + + ++ L Q + L+ + ++ + Sbjct: 1 MKSPEELKGIFEKYDKEGDG----QLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNG 56 Query: 70 DGKIGIVELAHVLPT 84 DG++ E ++ Sbjct: 57 DGEVSFEEFQVLVKK 71 >5MKE-A nrPDB Length = 968 Score = 36.0 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 11/79 (13%) Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 210 + GKL E+ + +G E F YDQDG+ + E+E Sbjct: 725 ISESLRQGGGKLNFDELRQ----------DLKGKGHTDAEIEAIFTKYDQDGDQELTEHE 774 Query: 211 LDALLKDLCEKNKQDLDIN 229 + DL EK ++DLD++ Sbjct: 775 HQQMRDDL-EKEREDLDLD 792 Score = 31.7 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 41/105 (39%), Gaps = 13/105 (12%) Query: 35 ELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRC 94 EL +LI++ + L+L + + ++ GK+ EL L Sbjct: 699 ELSDLIRK-GYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLK----------- 746 Query: 95 QQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVD 139 + + E + KYD D + E + ++D LEK + +D Sbjct: 747 GKGHTDAEIEAIFTKYDQDGDQELTEHEHQQ-MRDDLEKEREDLD 790 >2NCO-A nrPDB Length = 102 Score = 36.0 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Query: 104 MKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLE 163 + +++YD D SG ++ +E+ LKD + + T E + L++ D+N+DG + Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMG-MSNFTPTKEDVKIWLQMADTNSDGSVS 76 Query: 164 LTEMARLL 171 L E L+ Sbjct: 77 LEEYEDLI 84 Score = 34.0 bits (76), Expect = 0.071, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 34/84 (40%), Gaps = 2/84 (2%) Query: 61 FVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIET 120 +Y + G++ E+A +L + + K E+ + DT+ G + Sbjct: 20 LFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTK--EDVKIWLQMADTNSDGSVSL 77 Query: 121 EELKNFLKDLLEKANKTVDDTKLA 144 EE ++ + L+KA V+ L Sbjct: 78 EEYEDLIIKSLQKAGIRVEKQSLV 101 Score = 31.0 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 33/90 (36%), Gaps = 1/90 (1%) Query: 132 EKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEF 191 K + + + K +D + G+L+ E+A LL + ++ Sbjct: 2 SKPKYNPEVEAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDT-YAEMGMSNFTPTKEDV 60 Query: 192 NKAFELYDQDGNGYIDENELDALLKDLCEK 221 ++ D + +G + E + L+ +K Sbjct: 61 KIWLQMADTNSDGSVSLEEYEDLIIKSLQK 90 >2L0P-A nrPDB Length = 94 Score = 35.6 bits (80), Expect = 0.025, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 + +ELK L+ + + +D K + D ++K D N DG+++ E L+ Sbjct: 28 KLSKKELKELLQT---ELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAA 81 >2VTG-A nrPDB Length = 150 Score = 35.2 bits (79), Expect = 0.032, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 35/90 (38%), Gaps = 7/90 (7%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 + F E ++ FD + G ++ L+ ++++L + EMK + + Sbjct: 49 LTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLG------VPKTHLEMKKMISEVTGGVSDT 102 Query: 73 IGIVELAHVL-PTEENFLLLFRCQQLKSCE 101 I + +++ L L + K+ E Sbjct: 103 ISYRDFVNMMLGKRSAVLKLVMMFEGKANE 132 Score = 31.3 bits (69), Expect = 0.38, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 30/78 (38%), Gaps = 8/78 (10%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 F + + ++D ++ G I+ LK ++ L ++E T + + Sbjct: 52 FKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGV--------SDTI 103 Query: 163 ELTEMARLLPVQENFLLK 180 + ++ + + +LK Sbjct: 104 SYRDFVNMMLGKRSAVLK 121 >3H4S-E nrPDB Length = 135 Score = 34.8 bits (78), Expect = 0.037, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 36/115 (31%), Gaps = 10/115 (8%) Query: 82 LPTEENFLLLFRCQQLKSCE---EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV 138 + T+ +L +++ E E K + I E L+ + Sbjct: 18 METKYEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAESLRR-------NSGILG 70 Query: 139 DDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNK 193 + E M++ D + DG L TE L+ +++ + + Sbjct: 71 IEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEMMEDAETWLEKALTQE 125 >6MI5-X nrPDB Length = 117 Score = 34.4 bits (77), Expect = 0.048, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 106 TWRKYDTDHSGFIETEELKNF-----LKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 + K D D G ++ +ELK LK L + T+D + + K + +NDG Sbjct: 32 AFDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDG 91 Query: 161 KLELTEMA 168 ++ E+A Sbjct: 92 TIDARELA 99 Score = 31.3 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 36/108 (33%), Gaps = 25/108 (23%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS-----NNDGKLEL 164 +D D G I+ +E +K + D T A+ + D +NDG L+ Sbjct: 12 FDPDKDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGTLDK 71 Query: 165 TEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELD 212 E + Q F+ + D +G ID EL Sbjct: 72 KEYLAAVEAQ--------------------FKAANPDNDGTIDARELA 99 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 32/106 (30%), Gaps = 22/106 (20%) Query: 23 FDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVL 82 FD D G ++ KE D+ DG + EL + Sbjct: 12 FDPDKDGTIDLKEALAAGSA------------------AFDKLDPDKDGTLDAKELKGRV 53 Query: 83 PTEENFLLLFRCQQLKSCEEFMKT----WRKYDTDHSGFIETEELK 124 + L +E++ ++ + D+ G I+ EL Sbjct: 54 SEADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTIDARELA 99 Score = 27.5 bits (59), Expect = 5.9, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 26/70 (37%), Gaps = 7/70 (10%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ-------RDD 70 + D D G L+ KEL+ + E + + + + K ++ +D Sbjct: 31 AAFDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDND 90 Query: 71 GKIGIVELAH 80 G I ELA Sbjct: 91 GTIDARELAS 100 Score = 27.1 bits (58), Expect = 7.2, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 31/83 (37%), Gaps = 5/83 (6%) Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFN-----KAFELYDQDGNGY 205 + FD + DG ++L E + L + + KE + D D +G Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSAAFDKLDPDKDGTLDAKELKGRVSEADLKKLDPDNDGT 68 Query: 206 IDENELDALLKDLCEKNKQDLDI 228 +D+ E A ++ + D D Sbjct: 69 LDKKEYLAAVEAQFKAANPDNDG 91 >3POC-A nrPDB Length = 666 Score = 34.4 bits (77), Expect = 0.055, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 47/141 (33%), Gaps = 18/141 (12%) Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRK--------------YDTDHSGFI 118 IG + + + EN L + ++ + +K +R+ + G+ Sbjct: 116 IGYTRMDTLKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFGQSRWGYT 175 Query: 119 ETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFL 178 E+ + K E +Y K F N + E + + QE Sbjct: 176 TKEDFRAVAKGYRENHIPIDMIYMDIDYMQD-FKDFTVNEKNFPDFPEFVKEMKDQE--- 231 Query: 179 LKFQGIKMCGKEFNKAFELYD 199 L+ I G + K +E+Y+ Sbjct: 232 LRLIPIIDAGVKVEKGYEVYE 252 >1CB1-A nrPDB Length = 78 Score = 34.4 bits (77), Expect = 0.055, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 27/80 (33%), Gaps = 8/80 (10%) Query: 96 QLKSCEEFMKTWRKYD-TDHS-GFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKL 153 KS E + KY + + EELK ++ K D + + Sbjct: 2 AQKSPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSL------LKGPRTLDDLFQE 55 Query: 154 FDSNNDGKLELTEMARLLPV 173 D N DG++ E L+ Sbjct: 56 LDKNGDGEVSFEEFQVLVKK 75 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 29/74 (39%), Gaps = 4/74 (5%) Query: 12 TASQFFEIWLHFD-ADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 + ++ I+ + +G KE +++L QA + L+ + + + D Sbjct: 5 SPAELKSIFEKYAAKEGDPNQLSKE---ELKQLIQAEFPSLLKGPRTLDDLFQELDKNGD 61 Query: 71 GKIGIVELAHVLPT 84 G++ E ++ Sbjct: 62 GEVSFEEFQVLVKK 75 >5HYD-A nrPDB Length = 99 Score = 34.0 bits (76), Expect = 0.060, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 29/73 (39%), Gaps = 3/73 (4%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 + ELK L+ + + + K + D +++ D+N D +++ E ++ Sbjct: 28 KLSKGELKLLLQR---ELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAALTV 84 Query: 177 FLLKFQGIKMCGK 189 + ++ K Sbjct: 85 ACNDYFVEQLKKK 97 >2MA2-A nrPDB Length = 81 Score = 34.0 bits (76), Expect = 0.061, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 24/71 (33%), Gaps = 15/71 (21%) Query: 141 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQ 200 + + + + + FD + DG + E + + AF DQ Sbjct: 9 EHIEKMVESVFRNFDVDGDGHISQEEFQII-----RGNFPYL----------SAFGDLDQ 53 Query: 201 DGNGYIDENEL 211 + +G I E+ Sbjct: 54 NQDGCISREEM 64 Score = 33.3 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 19/69 (27%), Gaps = 15/69 (21%) Query: 100 CEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNND 159 + +R +D D G I EE + + D N D Sbjct: 12 EKMVESVFRNFDVDGDGHISQEEFQIIRGNF---------------PYLSAFGDLDQNQD 56 Query: 160 GKLELTEMA 168 G + EM Sbjct: 57 GCISREEMV 65 >2KGR-A nrPDB Length = 111 Score = 34.0 bits (76), Expect = 0.063, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 27/80 (33%), Gaps = 10/80 (12%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFD 155 S ++ + + +D SG + + + L + + + L D Sbjct: 9 PQSSRLKYRQLFNSHDKTMSGHLTGPQARTIL----------MQSSLPQAQLASIWNLSD 58 Query: 156 SNNDGKLELTEMARLLPVQE 175 + DGKL E + + + Sbjct: 59 IDQDGKLTAEEFILAMHLID 78 >2AUC-A nrPDB Length = 126 Score = 34.0 bits (76), Expect = 0.068, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 25/60 (41%) Query: 90 LLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDL 149 L + EE +K + +D + SGF+ ++KN L + + + L ++ Sbjct: 54 LTMCVHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSSE 113 Score = 28.3 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 19/37 (51%) Query: 184 IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCE 220 + +E K F +D + +G++ +N++ +L + Sbjct: 60 DRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGD 96 >6AGI-A nrPDB Length = 382 Score = 34.0 bits (76), Expect = 0.069, Method: Composition-based stats. Identities = 38/267 (14%), Positives = 77/267 (28%), Gaps = 63/267 (23%) Query: 14 SQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV----------- 62 + F + FD DG+ ++ KE L + ++ +K ++ E + + Sbjct: 105 AGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPT 164 Query: 63 ----------------------DQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSC 100 + + L T+ L+ F ++ K+ Sbjct: 165 NSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAE 224 Query: 101 EEFMKTWRKYD--------------TDHSGFIETEELKNFLKDLLEKANKTVDDTK---- 142 F +R D ++ I E+ + L N +V Sbjct: 225 LNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYS 284 Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLLPVQE------------NFLLKFQGIKMCGKE 190 + E + F S L + A L + + G+K Sbjct: 285 IPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHL 344 Query: 191 FNKAFELYDQDGNGYIDENELDALLKD 217 N F+++D D + + E ++KD Sbjct: 345 VNTVFKIFDVDKDDQLSYKEFIGIMKD 371 Score = 29.8 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 19/158 (12%), Positives = 50/158 (31%), Gaps = 6/158 (3%) Query: 22 HFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHV 81 F G L ++ + LQ + + + + + + Sbjct: 216 FFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEED-FAHILLRYTNVENT 274 Query: 82 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEEL----KNFLKDLLEKANKT 137 EN ++ + +EF ++ + I ++ +D ++A Sbjct: 275 SVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYV 334 Query: 138 VDDTKLAEY-TDLMLKLFDSNNDGKLELTEMARLLPVQ 174 K + + + + K+FD + D +L E ++ + Sbjct: 335 ATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDR 372 Score = 27.5 bits (59), Expect = 6.3, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 94 CQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLK 152 C K F + +DTD + ++ +E L+++ K N+ + K E ML+ Sbjct: 98 CILTKPHAGFRIAFNMFDTDGNEMVDKKEF-LVLQEIFRKKNEK-REIKGDEEKRAMLR 154 >2D58-A nrPDB Length = 107 Score = 33.6 bits (75), Expect = 0.087, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 32/80 (40%), Gaps = 6/80 (7%) Query: 13 ASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGK 72 F E ++ FD +G+G ++ L+ ++++L + E+K + + Sbjct: 31 LEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLG------VPKTHLELKKLIGEVSSGSGET 84 Query: 73 IGIVELAHVLPTEENFLLLF 92 + ++ + + +L Sbjct: 85 FSYPDFLRMMLGKRSAILKM 104 Score = 28.6 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 30/80 (37%), Gaps = 8/80 (10%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E F + + ++D + +G I+ LK L+ L ++ S + Sbjct: 32 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL--------ELKKLIGEVSSGSGE 83 Query: 161 KLELTEMARLLPVQENFLLK 180 + R++ + + +LK Sbjct: 84 TFSYPDFLRMMLGKRSAILK 103 >1IJ5-A nrPDB Length = 323 Score = 33.6 bits (75), Expect = 0.088, Method: Composition-based stats. Identities = 30/202 (14%), Positives = 63/202 (31%), Gaps = 44/202 (21%) Query: 16 FFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGI 75 +++L GSG ++L+ ++ K A +K G++ Sbjct: 124 LRQLFLSSAVSGSGKFSFQDLKQVL------AKYADTIPEGPLKKLFVMVENDTKGRMSY 177 Query: 76 VELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKAN 135 + L V + +RK DT+ +G + +E + L Sbjct: 178 ITLVAVANDLAALVAD---------------FRKIDTNSNGTLSRKEFREHFVRLG---- 218 Query: 136 KTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAF 195 D + + D + + +E L G+ + AF Sbjct: 219 -----FDKKSVQDALFRYADEDESDDVGFSEYVHL------------GLCLLVLRILYAF 261 Query: 196 ELYDQDGNGYIDENELDALLKD 217 +D+ G + + E+ +L+D Sbjct: 262 ADFDKS--GQLSKEEVQKVLED 281 >2PMY-A nrPDB Length = 91 Score = 33.3 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 28/80 (35%), Gaps = 12/80 (15%) Query: 92 FRCQQLKSCE--EFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDL 149 F+ E + D + SG +E EE + +L + + Sbjct: 16 FQGADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPAD----------AEA 65 Query: 150 MLKLFDSNNDGKLELTEMAR 169 + + D++ DG + E AR Sbjct: 66 VFQRLDADRDGAITFQEFAR 85 Score = 27.5 bits (59), Expect = 6.2, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 26/69 (37%), Gaps = 8/69 (11%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ ++ DA+ SG LE +E + L EL+ A + + DG Sbjct: 25 ELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADA--------EAVFQRLDADRDG 76 Query: 72 KIGIVELAH 80 I E A Sbjct: 77 AITFQEFAR 85 >1DJX-A nrPDB Length = 624 Score = 33.3 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 34/92 (36%), Gaps = 11/92 (11%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 RK D + + +ELK+FLK+L N VDD Y + + D + L Sbjct: 13 IHSCLRKADKNKDNKMNFKELKDFLKEL----NIQVDDG----YARKIFRECDHSQTDSL 64 Query: 163 ELTE---MARLLPVQENFLLKFQGIKMCGKEF 191 E E ++L + F+ + Sbjct: 65 EDEEIETFYKMLTQRAEIDRAFEEAAGSAETL 96 >1WY9-A nrPDB Length = 147 Score = 33.3 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 34/87 (39%), Gaps = 7/87 (8%) Query: 16 FFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGI 75 F ++ FD +G+G ++ L+ ++++L + E+K + + + Sbjct: 50 FKVKYMEFDLNGNGDIDIMSLKRMLEKLG------VPKTHLELKRLIREVSSGSEETFSY 103 Query: 76 VELAHVL-PTEENFLLLFRCQQLKSCE 101 + ++ L + + K+ E Sbjct: 104 SDFLRMMLGKRSAILRMILMYEEKNKE 130 Score = 32.1 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 36/93 (38%), Gaps = 8/93 (8%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 E F + ++D + +G I+ LK L+ L +++ S ++ Sbjct: 48 EAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL--------ELKRLIREVSSGSEE 99 Query: 161 KLELTEMARLLPVQENFLLKFQGIKMCGKEFNK 193 ++ R++ + + +L+ + + +K Sbjct: 100 TFSYSDFLRMMLGKRSAILRMILMYEEKNKEHK 132 >1QLS-A nrPDB Length = 99 Score = 32.9 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 24/58 (41%), Gaps = 3/58 (5%) Query: 114 HSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 ++ I E F+ L + D D M+K D ++DG+L+ E L+ Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKD---PGVLDRMMKKLDLDSDGQLDFQEFLNLI 82 >3CS1-A nrPDB Length = 219 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 47/157 (29%), Gaps = 22/157 (14%) Query: 18 EIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD-----GK 72 E++ FD + +G L E+ + E+ + + + K D+ G Sbjct: 52 ELFKKFDKNETGKLCYDEVYSGCLEVLK-LDEFTSRVRDITKRAFDKSRTLGSKLENKGS 110 Query: 73 IGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLE 132 VE L C E + + D + ++ EE K + L Sbjct: 111 EDFVEFLEF--------RLMLCYIYDFF-ELTVMFDEIDASGNMLVDEEEFKRAVPKLEA 161 Query: 133 KANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR 169 K D + K D N G + E A Sbjct: 162 WGAKVEDPA-------ALFKELDKNGTGSVTFDEFAA 191 >2KHN-A nrPDB Length = 121 Score = 32.5 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 27/68 (39%), Gaps = 10/68 (14%) Query: 115 SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQ 174 SGFI ++ +NF + L D NNDG+++ E + + + Sbjct: 46 SGFITGDQARNFFFQSGL----------PQPVLAQIWALADMNNDGRMDQVEFSIAMKLI 95 Query: 175 ENFLLKFQ 182 + L +Q Sbjct: 96 KLKLQGYQ 103 >2I18-A nrPDB Length = 64 Score = 32.1 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 22/67 (32%), Gaps = 12/67 (17%) Query: 103 FMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKL 162 ++ D D G + EE+ +F K E + D+N DG + Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHG------------IEKVAEQVMKADANGDGYI 54 Query: 163 ELTEMAR 169 L E Sbjct: 55 TLEEFLE 61 >2L50-A nrPDB Length = 102 Score = 32.1 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 116 GFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 I + L+ ++ N + DT + D +++ D+N+DG++ E L+ Sbjct: 30 NKISKSSFREMLQ---KELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLI 82 >2Y5I-A nrPDB Length = 99 Score = 31.7 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 24/73 (32%), Gaps = 3/73 (4%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 + ELK L + + K + ++ DSN D +++ E L+ Sbjct: 28 KLSKGELKEL---LNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAALTV 84 Query: 177 FLLKFQGIKMCGK 189 F + + Sbjct: 85 ACNDFFQEQQKKR 97 >4AOM-A nrPDB Length = 146 Score = 31.7 bits (70), Expect = 0.32, Method: Composition-based stats. Identities = 14/129 (10%), Positives = 35/129 (27%), Gaps = 20/129 (15%) Query: 8 SSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQ 67 + S + + G + ++L A + E+ Sbjct: 11 EEKVDESDVRIYFN--EKSSGGKISIDNASYNARKLGLAPSSIDEKKIKEL--------- 59 Query: 68 RDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 + + L + EE +K + +D + +G++ ++KN L Sbjct: 60 -YGDNLTYEQYLEYLS--------ICVHDKDNVEELIKMFAHFDNNCTGYLTKSQMKNIL 110 Query: 128 KDLLEKANK 136 + Sbjct: 111 TTWGDALTD 119 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 9/51 (17%), Positives = 22/51 (43%) Query: 184 IKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTY 234 K +E K F +D + GY+ ++++ +L + I+ + + Sbjct: 79 DKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAF 129 >3MZL-B nrPDB Length = 345 Score = 31.3 bits (69), Expect = 0.41, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 67/185 (36%), Gaps = 4/185 (2%) Query: 46 ARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMK 105 K +GLE + + + + I + + E L + EEF+K Sbjct: 39 NPKISGLESNTTLSEALKT--KDFKPLINQRLVKVIDDVNEEDWNLLEKLSMDGTEEFLK 96 Query: 106 TWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELT 165 +D D SG IE KN + ++ A K + L + M+ DSNN+ E Sbjct: 97 EALAFDNDESGNIEQTISKNLVSGNIKSAVKNSLENDL--LMEAMVIALDSNNERLKESV 154 Query: 166 EMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQD 225 + A L + +E + E D +I + + D+ ++N+ Sbjct: 155 KNAYFAKYGSKSSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEML 214 Query: 226 LDINN 230 + + + Sbjct: 215 IKLGD 219 >6DU8-A nrPDB Length = 805 Score = 31.3 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 38/91 (41%), Gaps = 7/91 (7%) Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGK 189 L + NKT+ +L + ++ + +++ + N L + + Sbjct: 584 LKQGYNKTLLRLRLRKERVSDVQKVLQGGEQEIQFEDFT-------NTLRELGHAEHEIT 636 Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDLCE 220 E F +D+DGN +DE E + + +DL E Sbjct: 637 ELTATFTKFDRDGNRILDEKEQEKMRQDLEE 667 Score = 31.0 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 50/132 (37%), Gaps = 9/132 (6%) Query: 11 ITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDD 70 + + + + + +G + +L +L+++ + L L E + V + Q + Sbjct: 555 MFLAIINDTYSEVKEELAGQKDELQLSDLLKQ-GYNKTLLRLRLRKERVSDVQKVLQGGE 613 Query: 71 GKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDL 130 +I + + L + E T+ K+D D + ++ +E + +DL Sbjct: 614 QEIQFEDFTNTLRELGHAEHEI--------TELTATFTKFDRDGNRILDEKEQEKMRQDL 665 Query: 131 LEKANKTVDDTK 142 E+ + + Sbjct: 666 EEERVALNTEIE 677 Score = 30.2 bits (66), Expect = 0.87, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 42/94 (44%), Gaps = 8/94 (8%) Query: 12 TASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDG 71 ++ + FD DG+ L+ KE ++++Q ++ + L+ E++ G Sbjct: 634 EITELTATFTKFDRDGNRILDEKE----QEKMRQDLEEERVALNTEIEKLGRSIVSSPQG 689 Query: 72 KIGIVELAHV---LPTEENFLLLFRCQQLKSCEE 102 K G E A + EE ++L R QL++ E Sbjct: 690 KSG-PEAARAGGWVSGEEFYMLTRRVLQLETVLE 722 >5CSF-A nrPDB Length = 95 Score = 31.3 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 ++ ELK + + + + +++ K E D +++ D++ DG+ + E + + Sbjct: 30 KLKKSELKELINN---ELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTT 86 Query: 177 FLLKF 181 +F Sbjct: 87 ACHEF 91 >2MJW-B nrPDB Length = 94 Score = 31.3 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 3/65 (4%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 + ELK ++ L + K + D +LK D+N D +++ +E + + Sbjct: 27 TLTKGELKVLMEKELPG---FLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAITS 83 Query: 177 FLLKF 181 K+ Sbjct: 84 ACHKY 88 >5X2E-A nrPDB Length = 80 Score = 31.3 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 31/85 (36%), Gaps = 10/85 (11%) Query: 101 EEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDG 160 + F+ + D D + I EL + + D + E + FD +N G Sbjct: 1 DSFINIFVSIDKDGTNVISYPEL-------EQYVAENNLDPSMVEKWKQL---FDPDNTG 50 Query: 161 KLELTEMARLLPVQENFLLKFQGIK 185 + L L ++ ++ F+ K Sbjct: 51 SITLETFCSKLGLKPAEIIDFREQK 75 Score = 28.3 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 23/82 (28%), Gaps = 14/82 (17%) Query: 58 MKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGF 117 + I EL + + K + +D D++G Sbjct: 3 FINIFVSIDKDGTNVISYPELEQYVAENNLDPSM-----------VEKWKQLFDPDNTGS 51 Query: 118 IETEELKNFLKDLLEKANKTVD 139 I L+ F L K + +D Sbjct: 52 IT---LETFCSKLGLKPAEIID 70 >1IQ3-A nrPDB Length = 110 Score = 31.0 bits (68), Expect = 0.51, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 28/73 (38%), Gaps = 10/73 (13%) Query: 98 KSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSN 157 + E ++ +R D S FI + K+ K+ ++ + +L D++ Sbjct: 19 EQREYYVNQFRSLQPDPSSFIS----GSVAKNFFTKSKLSIP------ELSYIWELSDAD 68 Query: 158 NDGKLELTEMARL 170 DG L L E Sbjct: 69 CDGALTLPEFCAA 81 >3NSO-A nrPDB Length = 101 Score = 31.0 bits (68), Expect = 0.56, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 127 LKDLLEKANKTVDDTKLAE-YTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIK 185 LK+LL+K T T+ E + + + D+N D +++ E R L + ++ Sbjct: 34 LKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDC 93 Query: 186 MCG 188 Sbjct: 94 PSE 96 >4GFT-A nrPDB Length = 69 Score = 31.0 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 19/41 (46%) Query: 96 QLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 + EE +K + +D + +G++ ++KN L + Sbjct: 2 DKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTD 42 Score = 30.6 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 23/52 (44%) Query: 183 GIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTY 234 G K +E K F +D + GY+ ++++ +L + I+ + + Sbjct: 1 GDKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQEAIDALNAF 52 >2WCE-A nrPDB Length = 95 Score = 31.0 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 24/57 (42%), Gaps = 3/57 (5%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 + ELK L L K + D + D + + D+N D +++ E ++ + Sbjct: 30 TLSKGELKQLLTKELANTIKNIKDKAV---IDEIFQGLDANQDEQVDFQEFISMVAI 83 >2M7L-A nrPDB Length = 144 Score = 30.6 bits (67), Expect = 0.72, Method: Composition-based stats. Identities = 11/100 (11%), Positives = 32/100 (32%), Gaps = 10/100 (10%) Query: 97 LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDS 156 + +EF +++ +D +H G ++ E ++ L + D + Sbjct: 8 AEQMQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQ--YDAIYNNVTK 65 Query: 157 NNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFE 196 +G + + + + ++ N+ F Sbjct: 66 GENG-VSFDNYVQYMKEK-------NDENPSPEQLNEIFS 97 >6DS2-B nrPDB Length = 114 Score = 29.8 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 23/52 (44%), Gaps = 2/52 (3%) Query: 122 ELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPV 173 E K ++ L+ N + K + + +++ D+N D +L E L+ Sbjct: 36 EFKELVRKDLQ--NFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMAR 85 >5CUU-A nrPDB Length = 414 Score = 29.4 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 6/79 (7%) Query: 163 ELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKN 222 +TE + ++ F L M + + F +D GY++E +++ + K L + Sbjct: 57 NVTEFDLVAYGKDEFTL-----SMEKRVMARMFSAFDVTQLGYLEERKIEHMCKYLG-RV 110 Query: 223 KQDLDINNITTYKKNIMAL 241 + D+ + + I Sbjct: 111 MNEDDVKQMKSEINAIDGH 129 Score = 29.0 bits (63), Expect = 1.8, Method: Composition-based stats. Identities = 13/94 (13%), Positives = 31/94 (32%), Gaps = 15/94 (15%) Query: 74 GIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEK 133 + E V ++ F L + + + +D G++E ++++ K L Sbjct: 57 NVTEFDLVAYGKDEFTLSMEKRV------MARMFSAFDVTQLGYLEERKIEHMCKYLGRV 110 Query: 134 ANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 167 N+ +E + DG + + Sbjct: 111 MNEDDVKQMKSEINAI---------DGHITFEKF 135 Score = 29.0 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 28/59 (47%), Gaps = 7/59 (11%) Query: 20 WLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVEL 78 + FD GYLE ++++++ + L + + ++ +MK+ ++ G I + Sbjct: 84 FSAFDVTQLGYLEERKIEHMCKYLGRVMNEDDVK---QMKSEINAID----GHITFEKF 135 >5HLO-A nrPDB Length = 94 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 25/73 (34%), Gaps = 2/73 (2%) Query: 101 EEFMKTW-RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEY-TDLMLKLFDSNN 158 E K D H + +D L+K +T + + D+ K D N Sbjct: 4 TELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKGADVWFKELDINT 63 Query: 159 DGKLELTEMARLL 171 DG + E L+ Sbjct: 64 DGAVNFQEFLILV 76 >6QAA-A nrPDB Length = 557 Score = 28.6 bits (62), Expect = 2.5, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 37/115 (32%), Gaps = 5/115 (4%) Query: 68 RDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFL 127 D + ++ L + +L + + + + D++ I +E + L Sbjct: 323 DGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGL 382 Query: 128 KDLLEKANKTVDDTKLAEYTDLMLKLFDSN-----NDGKLELTEMARLLPVQENF 177 K ++ ++ L YTD + N D + + L + F Sbjct: 383 KIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKF 437 >2MHH-A nrPDB Length = 96 Score = 28.6 bits (62), Expect = 2.5, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 29/89 (32%), Gaps = 10/89 (11%) Query: 130 LLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGK 189 L+ + + L D+N D L+ E + L + + Sbjct: 3 LVPRGSHMASKRDKIADIQEALAHADANADQHLDFDEWRQELKCRGH----------ADA 52 Query: 190 EFNKAFELYDQDGNGYIDENELDALLKDL 218 + F YD DG+ +D E + DL Sbjct: 53 DIEAVFAKYDVDGDRVLDAEEQMKMAHDL 81 >3AHE-A nrPDB Length = 845 Score = 28.6 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 55/158 (34%), Gaps = 11/158 (6%) Query: 60 TFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIE 119 F+D + V LA TEE+F +L + EE D + F+ Sbjct: 326 KFIDGKKTEGSWRAHQVPLASARDTEEHFEVLKGWMESYKPEELFNADGSIKDDVTAFMP 385 Query: 120 TEELKNFLKDLLEKANKTVDDTKLAE---YTDLMLKLFDSNNDGKLELTE----MAR-LL 171 EL+ + +D KL E Y +K + + G++E R ++ Sbjct: 386 KGELR-IGANPNANGGVIREDLKLPELDQYEVTGVKEY-GHGWGQVEAPRALGAYCRDII 443 Query: 172 PVQENFLLKFQGIKMCGKEFNKAFELYDQD-GNGYIDE 208 + F + N +E+ D+ NGY+ Sbjct: 444 KNNPDSFRIFGPDETASNRLNATYEVTDKQWDNGYLSG 481 >2IXN-A nrPDB Length = 310 Score = 28.6 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 7/44 (15%), Positives = 20/44 (45%) Query: 150 MLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNK 193 ++K DS+ GK+E + + +L+ + + ++ + Sbjct: 71 VIKDADSSRFGKVEFRDFYDEVSRNSRKILRSEFPSLTDEQLEQ 114 >2JMM-A nrPDB Length = 156 Score = 28.6 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 8/12 (66%), Positives = 9/12 (75%) Query: 199 DQDGNGYIDENE 210 D+DGNGYI E Sbjct: 90 DKDGNGYISAAE 101 >5ZCR-A nrPDB Length = 728 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 40/127 (31%), Gaps = 11/127 (8%) Query: 125 NFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMAR----------LLPVQ 174 +++ + + + + N+ + + + L+ Sbjct: 527 KVIREAKVHTTWENPNLEYEKKVLGFIDEVFENSSFRNDFDNFEKKIVYFGYMKSLVATT 586 Query: 175 ENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTY 234 FL G E F L D D +D +L LL +L EKN + D Y Sbjct: 587 LKFLSPGVPDIYQGTEV-WRFLLTDPDNRMAVDFRKLRELLNNLTEKNLELSDPRTKMLY 645 Query: 235 KKNIMAL 241 K ++ L Sbjct: 646 VKKLLQL 652 >1KQV-A nrPDB Length = 79 Score = 28.3 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 12/27 (44%) Query: 147 TDLMLKLFDSNNDGKLELTEMARLLPV 173 D + + D N DG++ E L+ Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKK 76 >1J37-A nrPDB Length = 607 Score = 27.9 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 32/100 (32%), Gaps = 5/100 (5%) Query: 95 QQLKSCEEFMKTWRKYDTDHS----GFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLM 150 ++ E +R TD + I EL F+K++ K + +E Sbjct: 25 KRTNVETEAAWAYRSAITDENEKKKNEISA-ELAKFMKEVASDTTKFQWRSYQSEDLKRQ 83 Query: 151 LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKE 190 K L + A LL F +K+C + Sbjct: 84 FKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYK 123 >4WNZ-A nrPDB Length = 301 Score = 27.9 bits (60), Expect = 4.2, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 30/73 (41%), Gaps = 6/73 (8%) Query: 123 LKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQ 182 L F +DL K T++ E TD + + D K+ L E A L+ + +L+ Sbjct: 110 LNRFKRDLELAGVKNF-QTEIPELTDTAIASEEITVDNKVILEEFAILIQKDDKGILE-- 166 Query: 183 GIKMCGKEFNKAF 195 K +AF Sbjct: 167 ---SVVKAIEQAF 176 >4BHK-A nrPDB Length = 171 Score = 27.5 bits (59), Expect = 5.8, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 28/85 (32%), Gaps = 1/85 (1%) Query: 129 DLLEKANKTVDDTKLAEYTDLMLKLFDSNN-DGKLELTEMARLLPVQENFLLKFQGIKMC 187 ++ E + + N D +L E + + K +G K Sbjct: 4 EVGEDGEERPREHPFIVTEPGEPAKGKKNGLDYLFDLYEQCGKFLEEVQHIAKEKGEKCP 63 Query: 188 GKEFNKAFELYDQDGNGYIDENELD 212 K N+ F G GYI++ ++ Sbjct: 64 SKVTNEVFRHAKLTGAGYINKPKMR 88 >6EMI-A nrPDB Length = 532 Score = 27.5 bits (59), Expect = 6.1, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 17/39 (43%) Query: 110 YDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTD 148 + D+ I +E + LK ++ ++ L YTD Sbjct: 340 FSKDNDSIITRKEFQEGLKVFFPNVSEFGKESILFHYTD 378 >4YBH-B nrPDB Length = 92 Score = 27.5 bits (59), Expect = 6.1, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 21/55 (38%), Gaps = 5/55 (9%) Query: 117 FIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 171 + +ELK ++ L +K D +++ D N D ++ E L Sbjct: 30 TLSKKELKELIQKELTIGSKLQDAE-----IARLMEDLDRNKDQEVNFQEYVTFL 79 >4A0K-A nrPDB Length = 742 Score = 27.5 bits (59), Expect = 6.4, Method: Composition-based stats. Identities = 27/176 (15%), Positives = 56/176 (31%), Gaps = 8/176 (4%) Query: 3 ESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFV 62 E HL +I + F+ + G L + + + + K ++S +T V Sbjct: 523 EVHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSL-FQTLV 581 Query: 63 DQYGQRDDG-KIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETE 121 DG +++A + E L K+ K D FI Sbjct: 582 LLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNG 641 Query: 122 ELKNFLKDLLEKANKT-VDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQEN 176 E K+ L + + + T+ + + D + R++ +++ Sbjct: 642 EFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAI-----VRIMKMRKT 692 >5VP3-A nrPDB Length = 206 Score = 27.1 bits (58), Expect = 7.6, Method: Composition-based stats. Identities = 26/207 (12%), Positives = 68/207 (32%), Gaps = 14/207 (6%) Query: 26 DGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTE 85 D + + L+++ + + ++ + D + DGK+ + E+ + Sbjct: 4 DETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDRM 63 Query: 86 ENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETE---ELKNFLKDLLEKANKTVDDTK 142 + Q K + D ++ E E + + + + + Sbjct: 64 RQLVNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEPSL 123 Query: 143 LAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDG 202 +A ++ + D + DG +++ E+ ++ + + + F+ D D Sbjct: 124 IALLSNAYYDVLDDDGDGTVDVEELKTMMKAFD----------VPQEAAYTFFQKADTDK 173 Query: 203 NGYIDENELDALLKDL-CEKNKQDLDI 228 G ++ EL L + E D Sbjct: 174 TGKLERPELVHLFRKFWMEPYDPQWDG 200 >6MZL-S nrPDB Length = 124 Score = 26.7 bits (57), Expect = 9.7, Method: Composition-based stats. Identities = 12/91 (13%), Positives = 36/91 (39%), Gaps = 6/91 (6%) Query: 120 TEELKNFLKDLLEKANKTVDDTKLAE------YTDLMLKLFDSNNDGKLELTEMARLLPV 173 ++EL+ + + N + + E T++ K G++++ ++ L+ Sbjct: 33 SKELRCMMYGFGDDQNPYTESVDILEDLVIEFITEMTHKAMSIGRQGRVQVEDIVFLIRK 92 Query: 174 QENFLLKFQGIKMCGKEFNKAFELYDQDGNG 204 + + + +E +A + +D+ G Sbjct: 93 DPRKFARVKDLLTMNEELKRARKAFDEANYG 123 >3ABB-A nrPDB Length = 408 Score = 26.7 bits (57), Expect = 9.8, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 45/143 (31%), Gaps = 4/143 (2%) Query: 19 IWLHFDADGSGYLEGKELQNLIQELQQARKKA-GLELSPEMKTFVDQYGQRDDGKIGIVE 77 + D + ++ + LI R A L + +D + G + Sbjct: 91 AFPLIGVDDP--VHARQRRMLIPSFGVKRMNAIRPRLQSLVDRLLDDMLAKGPGADLVSA 148 Query: 78 LAHVLPTEENFLLL-FRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANK 136 A +P+ LL EE + + T EL +L L+ + Sbjct: 149 FALPVPSVAICELLGVPYGDHDFFEECSRNFVGAATSAEADAAFGELYTYLHGLVGRKQA 208 Query: 137 TVDDTKLAEYTDLMLKLFDSNND 159 +D L E L+ D ++D Sbjct: 209 EPEDGLLDELIARQLEEGDLDHD 231 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.121 0.286 Lambda K H 0.267 0.0369 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,595,062 Number of Sequences: 36641 Number of extensions: 313325 Number of successful extensions: 4678 Number of sequences better than 10.0: 321 Number of HSP's better than 10.0 without gapping: 421 Number of HSP's successfully gapped in prelim test: 109 Number of HSP's that attempted gapping in prelim test: 1605 Number of HSP's gapped (non-prelim): 1693 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.1 bits)