BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05825 (746 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1FEP-A nrPDB 1489 0.0 5M9B-A nrPDB 896 0.0 5FP2-A nrPDB 786 0.0 5FR8-A nrPDB 626 e-179 2HDF-A nrPDB 267 1e-71 1NQH-A nrPDB 88 2e-17 3FHH-A nrPDB 70 5e-12 4EPA-A nrPDB 53 4e-07 1FCP-A nrPDB 51 1e-06 5FOK-A nrPDB 50 4e-06 3QLB-A nrPDB 49 9e-06 6BPM-C nrPDB 48 2e-05 5FQ8-B nrPDB 47 3e-05 1KMO-A nrPDB 45 1e-04 6FOK-A nrPDB 44 3e-04 5NEC-A nrPDB 43 6e-04 5FP1-A nrPDB 42 8e-04 6E4V-A nrPDB 41 0.002 6H7F-A nrPDB 39 0.006 4ZGV-A nrPDB 39 0.011 2W78-A nrPDB 38 0.013 1XKH-A nrPDB 38 0.013 3EFM-A nrPDB 35 0.16 3V8X-A nrPDB 34 0.24 1XKW-A nrPDB 33 0.39 4B7O-A nrPDB 33 0.63 4AIP-A nrPDB 33 0.65 1ICX-A nrPDB 32 1.2 4RDT-A nrPDB 30 3.9 >1FEP-A nrPDB Length = 724 Score = 1489 bits (3856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 724/724 (100%), Positives = 724/724 (100%) Query: 23 QEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGN 82 QEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGN Sbjct: 1 QEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGN 60 Query: 83 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE 142 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE Sbjct: 61 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE 120 Query: 143 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT 202 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT Sbjct: 121 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT 180 Query: 203 GPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWD 262 GPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWD Sbjct: 181 GPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWD 240 Query: 263 FAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNG 322 FAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNG Sbjct: 241 FAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNG 300 Query: 323 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN 382 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN Sbjct: 301 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN 360 Query: 383 QTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMEL 442 QTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMEL Sbjct: 361 QTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMEL 420 Query: 443 TDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYIL 502 TDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYIL Sbjct: 421 TDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYIL 480 Query: 503 YSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGY 562 YSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGY Sbjct: 481 YSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGY 540 Query: 563 VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLS 622 VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLS Sbjct: 541 VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLS 600 Query: 623 IIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS 682 IIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS Sbjct: 601 IIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS 660 Query: 683 ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSV 742 ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSV Sbjct: 661 ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSV 720 Query: 743 NTHF 746 NTHF Sbjct: 721 NTHF 724 >5M9B-A nrPDB Length = 724 Score = 896 bits (2316), Expect = 0.0, Method: Compositional matrix adjust. Identities = 440/720 (61%), Positives = 547/720 (75%), Gaps = 17/720 (2%) Query: 33 DDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNR 92 + T+V TA E+ QAPGVS ITA++I K P + D+S+IIRTMPGVNLTGNS+SGQRGNNR Sbjct: 16 EQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNR 75 Query: 93 QIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAA 152 QIDIRGMGPENTLIL+DGKPVSSRNSVR GWRGERD+RGDT+WVP + +ERIEV+RGPAA Sbjct: 76 QIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAA 135 Query: 153 ARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFR 212 ARYGNGAAGGVVNIITK+ E HG+ Y N P+HK EGA++R +F L GPL + S+R Sbjct: 136 ARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYR 195 Query: 213 LYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELE 272 +YGN+ KT +D WDIN GH+S R G A TLPAGREGV NKDI+G++ W P Q+LE E Sbjct: 196 VYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFE 255 Query: 273 AGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYE 332 AG+SRQGN+Y GDTQNTNS++Y + G ETNR+YR+ Y++T G WD G + + ++QYE Sbjct: 256 AGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLA-YLQYE 314 Query: 333 HTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN 392 TRNSRI EGLAGGTEG F+ F L D+ H EVNLP+ QTLTLG+EW Sbjct: 315 KTRNSRINEGLAGGTEGIFDPN-NAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEWT 373 Query: 393 QQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGL 452 +Q++ D SSNTQ T GG+I G++ +RS S A IFSLFAE+N+EL T++TPGL Sbjct: 374 EQKLDDPSSNTQ---NTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGL 430 Query: 453 RFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYAS 512 R+DHH IVG+NWSP+LN+S L + TLK GIARAYKAP+LYQ NP+Y+LYS+GQGCY Sbjct: 431 RWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQ 490 Query: 513 AGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVG- 571 + CYL+GND LKAETS+NKE+G+E+ DG +AG+T+FRNDY+NKIE+G V + G Sbjct: 491 STSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGK 550 Query: 572 -----TDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPE 626 +YQW+NVPKAVVEGLEG+L +P+++ + W+NN+TYML+S+NK TGD LS+ P Sbjct: 551 GDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPR 610 Query: 627 YTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWD 686 YTLNS L WQA +DLS+Q T TWYGKQ+PKKY+Y G G ++SPY+I GL T+ Sbjct: 611 YTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYR 670 Query: 687 VTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 746 ++KN+SL GVDNLFDKRL+RAGNAQ G I GAGA TYNEPGRT+Y S+ F Sbjct: 671 LSKNLSLGAGVDNLFDKRLFRAGNAQ------GVVGIDGAGAATYNEPGRTFYTSLTASF 724 >5FP2-A nrPDB Length = 725 Score = 786 bits (2030), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/727 (56%), Positives = 523/727 (71%), Gaps = 32/727 (4%) Query: 27 DTPVSHDDTIVVTAAEQNL-QAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTS 85 ++ V D +V+ AEQ L QAPGVS ITA++IRK P D+S+IIRTMPGVNLTGNS+S Sbjct: 16 ESVVQLGDEVVLGTAEQELKQAPGVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTGNSSS 75 Query: 86 GQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIE 145 GQRGNNRQIDIRGMGPENTLIL+DGKPVSSRNSVR GWRGERDTRGD++WVPPE +ERIE Sbjct: 76 GQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDTRGDSNWVPPEEVERIE 135 Query: 146 VLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPL 205 VLRGPAAARYG+GAAGGVVNIITK+ + GS + N PE ++GAT+R NFSL+GPL Sbjct: 136 VLRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPL 195 Query: 206 GDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAP 265 + SFR YG+ +KT +D DIN GH + T AGREGV N+D++G++ W P Sbjct: 196 TEALSFRAYGSANKTDSDDTDINLGHTVNPSRTV-----AGREGVRNRDLSGMLSWQVTP 250 Query: 266 LQSLELEAGYSRQGNLYAGDTQNTNSDSYTR--SKYGDETNRLYRQNYALTWNGGWDNGV 323 Q ++ EAG+SRQGN+YAGDTQN N + T+ + G ETNR+YR+NYA+T NG W G Sbjct: 251 DQVVDFEAGFSRQGNIYAGDTQNNNGTANTQGLADDGAETNRMYRENYAITHNGTWSFG- 309 Query: 324 TTSNWV-QYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN 382 TS +V QY+ TRN+R+ EGLAG EG+ A + F L++ L E+NLP+ L Sbjct: 310 -TSRFVAQYDSTRNNRLEEGLAGSVEGQIG--ADRSFSASKLENYRLSGELNLPLHALFE 366 Query: 383 QTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMEL 442 Q LT+G EWN++ + D SS Q G+++ + RSP SKAEI +L+ E+N+EL Sbjct: 367 QVLTVGAEWNKETLNDPSSLKQGFVGSDSLPGTPAAGS--RSPKSKAEIRALYVEDNIEL 424 Query: 443 TDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYIL 502 T++TPGLR D HS G NWSP+LN SQ LG+ FT+K GIARA+KAP+LYQ+NPNY+L Sbjct: 425 RPGTMLTPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAPNLYQSNPNYLL 484 Query: 503 YSKGQGC--YASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEA 560 Y++G GC S+GGCYL GN++L AETS+NKE+G+EF+RDGW+AG+T+FRNDY+NKI A Sbjct: 485 YTRGNGCPIQTSSGGCYLVGNENLDAETSVNKELGIEFRRDGWVAGLTYFRNDYKNKIVA 544 Query: 561 GYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDR 620 +GQ G ++ QW N KAVVEGLEG+L VP+ E + W+ N+TYML+S++K TG+ Sbjct: 545 PLDVMGQTGTGNNILQWSNAKKAVVEGLEGNLLVPLHEDLSWSTNLTYMLQSKDKDTGNP 604 Query: 621 LSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKY-NYKGQPAVGPETKEISPYSIV 679 LS+IPEYTLNSTL WQA E LS Q T T YG+Q+P K+ + P V KE+ Y I Sbjct: 605 LSVIPEYTLNSTLDWQASERLSTQLTSTIYGRQEPPKHGTSRNTPVV--SRKEVGTYGIW 662 Query: 680 GLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWY 739 G+SA + ++N+S+ GGV NLFDKRL+R GN+ AGA TYNEPGR +Y Sbjct: 663 GVSAGYTFSENLSVRGGVSNLFDKRLYRQGNS------------FDAGAATYNEPGRAYY 710 Query: 740 MSVNTHF 746 +S+ T F Sbjct: 711 VSMTTSF 717 >5FR8-A nrPDB Length = 733 Score = 626 bits (1614), Expect = e-179, Method: Compositional matrix adjust. Identities = 351/759 (46%), Positives = 476/759 (62%), Gaps = 68/759 (8%) Query: 21 QAQEPTDTPVS--HDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVN 78 QA++ + P +TI VTA EQ Q+ GVS IT +++ K PV D+S +R MPGVN Sbjct: 10 QAEQTLEKPAEPVKLETIFVTAEEQVKQSLGVSVITKEDLEKLPVRNDISDYVRRMPGVN 69 Query: 79 LTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPP 138 LTGNS +GQRGNNRQIDIRGMGPENTLIL+DGKP++SRNSVR GW+GERDTRGD++WVP Sbjct: 70 LTGNSATGQRGNNRQIDIRGMGPENTLILVDGKPINSRNSVRYGWKGERDTRGDSNWVPA 129 Query: 139 EMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTN 198 E IE IEVLRGPAAARYG+GAAGGVVNIITKK + E HGS + Y + PE +EG++ R Sbjct: 130 EAIESIEVLRGPAAARYGSGAAGGVVNIITKKVTNETHGSVEFYTSQPEDSKEGSSNRVG 189 Query: 199 FSLTGPL-GDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDING 257 F+++GPL D S+RLYGN +KT+AD DIN+ S AGREGV NKDI+G Sbjct: 190 FNVSGPLIKDVLSYRLYGNYNKTEADDVDINKSIGST---------AAGREGVKNKDISG 240 Query: 258 VVRWDFAPLQSLELEAGYSRQGNLYAGDTQ---NTNSDSYTRSKYGDETNRLYRQNYALT 314 + W Q++ L+ S+QGN+Y+GD+Q N +D+ G ETN +YR +YALT Sbjct: 241 RLAWQATDQQTVLLDISSSKQGNIYSGDSQLNANAEADAILSQLIGKETNTMYRDSYALT 300 Query: 315 WNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFN---EKATQDFVDIDLDDVMLHS 371 G W G + QY+ T N R+PEGLAG EGK N +KAT L+ + + Sbjct: 301 HEGDWSWG-KSKLVAQYDKTHNKRLPEGLAGSVEGKINNLDDKATS-----RLETLRFNG 354 Query: 372 EVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEI 431 E N+P ++ + Q LT+GTEW + R KD S TQ + +G D ++ DRS ++ I Sbjct: 355 EANIPFEYYLPQVLTVGTEWVEDRFKDNVSTTQGKDSSGSGYG-DQLAKGDRSKM-ESRI 412 Query: 432 FSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAP 491 S + E+N+++TDST V GLRFD HS G+NWSP+LNI+Q L D FTLK G+A+AYKAP Sbjct: 413 ASAYIEDNLKVTDSTDVVLGLRFDDHSKSGSNWSPSLNITQKLNDYFTLKGGVAKAYKAP 472 Query: 492 SLYQTNPNYILYSKGQGCYAS-AGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWF 550 ++YQ Y+L + G GC A+ C LQGN DLK ETS+NKE+G++F++D A +TWF Sbjct: 473 NMYQNAEGYLLSTNGNGCPANIESRCLLQGNGDLKPETSVNKELGIQFQKDIVNASLTWF 532 Query: 551 RNDYRNKIEAGYVAVG----------QNAVGT---DLYQWDNVPKAVVEGLEGSLNVPVS 597 RNDY++KI AG VG AV ++ +W+N PKA+++G EGSL + Sbjct: 533 RNDYKDKIVAGTHVVGTVDGSSTNANTGAVTNTKWNILRWENTPKALIQGFEGSLGLDFG 592 Query: 598 ETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKK 657 + + WTNN TYM+ S++K TG+ LS++P YT+NS + + L + FT YG+Q+ ++ Sbjct: 593 D-IRWTNNFTYMMDSKDKQTGNPLSLVPIYTINSIFDYDITDQLDVNFVFTQYGRQKSRQ 651 Query: 658 YNYK----------GQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWR 707 + A+ P T + YS G++ + + +S GV NLFDK++ R Sbjct: 652 FAENRLESGIGSGGANSALKPST--VKSYSTAGINVGYKFSDQISTRVGVSNLFDKQILR 709 Query: 708 AGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 746 N+ + TYNEPGR +Y S+ F Sbjct: 710 DSNSISQ---------------TYNEPGRAYYASLKYSF 733 >2HDF-A nrPDB Length = 639 Score = 267 bits (683), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 244/746 (32%), Positives = 357/746 (47%), Gaps = 146/746 (19%) Query: 34 DTIVVTAA--EQNLQ-APG-VSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRG 89 +T+VVTA+ EQNL+ AP +S IT +++++ PV +++ +++ +PGV LT G Sbjct: 7 ETMVVTASSVEQNLKDAPASISVITQEDLQRKPV-QNLKDVLKEVPGVQLT------NEG 59 Query: 90 NNRQ-IDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLR 148 +NR+ + IRG+ TLIL+DGK V+SRN+V R D +W+P + IERIEV+R Sbjct: 60 DNRKGVSIRGLDSSYTLILVDGKRVNSRNAVF------RHNDFDLNWIPVDSIERIEVVR 113 Query: 149 GPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGD- 207 GP ++ YG+ A GGVVNIITKK +W G+ EH++ G T F +GPL D Sbjct: 114 GPMSSLYGSDALGGVVNIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDG 173 Query: 208 EFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQ 267 + YG+L K + D + T T EG ++D G V + + P Q Sbjct: 174 VLGMKAYGSLAKREKD--------DPQNSTTTDTGETPRIEGFSSRD--GNVEFAWTPNQ 223 Query: 268 SLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSN 327 + + AG Y D Q+ +SDS + NRL RQNY+++ NG WD G TS Sbjct: 224 NHDFTAG-------YGFDRQDRDSDSLDK-------NRLERQNYSVSHNGRWDYG--TSE 267 Query: 328 WVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTL 387 Y ++ P G + +E T D + LP+ +NQ LT+ Sbjct: 268 LKYYGEKVENKNP----GNSSPITSESNTVD------------GKYTLPLT-AINQFLTV 310 Query: 388 GTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTI 447 G E +M D + LTG G S+ + A ++LF E+ + + Sbjct: 311 GGEMRHDKMSDAVN----LTG--------GTSSK-----TSASQYALFVEDEWRIFEPLA 353 Query: 448 VTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQ 507 +T G+R D H G +WSP + D T+K G A A+KAPSL Q +P++ S Sbjct: 354 LTTGVRMDDHETYGEHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNS--- 410 Query: 508 GCYASAGGCYLQGNDDLKAETSINKEIGLEFK-RDGWLAG----VTWFRNDYRNKIE--- 559 C G C + G+ DLK ETS + E+GL + +GWL G VT FRND +++I Sbjct: 411 -C---RGACKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISR 466 Query: 560 -------AGY-----VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNIT 607 GY G N ++ + NV KA ++G+E L +P ++ + N T Sbjct: 467 TSDVNAAPGYQNFVGFETGANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYT 526 Query: 608 Y-----MLKSENKTTGDRLSIIPEYTLNSTLSWQ--AREDLSMQTTFTWYGKQQPKKYNY 660 Y + ENK LS +P +T N TL W+ A ED SM + + G+++ Sbjct: 527 YNDGRDVSNGENKP----LSDLPFHTANGTLDWKPLALEDWSMYMSGHYTGQKR------ 576 Query: 661 KGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGA 720 A K Y+I A W VTK+V L GV NL DK L R Sbjct: 577 ----ADSATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSR------------- 619 Query: 721 NYIAGAGAYTYNEPGRTWYMSVNTHF 746 Y+YNE GR ++M+V+ F Sbjct: 620 ------DDYSYNEDGRRYFMAVDYRF 639 >1NQH-A nrPDB Length = 594 Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 171/720 (23%), Positives = 277/720 (38%), Gaps = 153/720 (21%) Query: 34 DTIVVTA-----AEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQR 88 DT+VVTA + AP + +T +I + + V+ ++R +PGV++T N SGQ Sbjct: 6 DTLVVTANRFEQPRSTVLAP-TTVVTRQDIDRWQ-STSVNDVLRRLPGVDITQNGGSGQL 63 Query: 89 GNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLR 148 + I IRG + L+LIDG VR G + D S P +++R+E +R Sbjct: 64 SS---IFIRGTNASHVLVLIDG--------VRLNLAGVSGS-ADLSQFPIALVQRVEYIR 111 Query: 149 GPAAARYGNGAAGGVVNIITKKGS--GEWHGSWDAYFNAPEHKEEGATKRTNFSLT--GP 204 GP +A YG+ A GGVVNIIT + E W G+ N+ ++ Sbjct: 112 GPRSAVYGSDAIGGVVNIITTRDEPGTEISAGW------------GSNSYQNYDVSTQQQ 159 Query: 205 LGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFA 264 LGD+ L G+ T G+ G T +G ++K + G + +F Sbjct: 160 LGDKTRVTLLGDYAHT--------HGYDVVAYGNTGTQAQTDNDGFLSKTLYGALEHNFT 211 Query: 265 PLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNY--ALTWNGGWDNG 322 S G+ R Y D + Y+ +T +LY Q++ L +NG Sbjct: 212 DAWS-----GFVRG---YGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRYNG---EL 260 Query: 323 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN 382 + + Y H+++ G+++ AT D M V + +V Sbjct: 261 IKSQLITSYSHSKDYNYDPHY-----GRYDSSATL--------DEMKQYTVQWANNVIVG 307 Query: 383 Q-TLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNME 441 ++ G +W +Q T TG DG + Y ++ Sbjct: 308 HGSIGAGVDWQKQ-----------TTTPGTGYVEDGYDQRNTGIYLTG----------LQ 346 Query: 442 LTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYI 501 R D +S G + + + + + +YKAP+L Q Sbjct: 347 QVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQ------ 400 Query: 502 LYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAG 561 LY G Y GN +L E S E E G AGV W + YRN + Sbjct: 401 LY----GFY---------GNPNLDPEKSKQWEGAFE----GLTAGVNWRISGYRNDV--- 440 Query: 562 YVAVGQNAVGTDLYQWD-------NVPKAVVEGLEGSLNV---PVSETVMWTNNITYMLK 611 +DL +D N KA ++G+E + N P++ TV + + Sbjct: 441 ----------SDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYD-----YVD 485 Query: 612 SENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETK 671 + N T L + + L WQ D T+ + G + K Y+ + +T Sbjct: 486 ARNAITDTPLLRRAKQQVKYQLDWQLY-DFDWGITYQYLGTRYDKDYS-----SYPYQTV 539 Query: 672 EISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTY 731 ++ S+ L+ + VT ++++ G + NLFDK QT AG Y +G+YT+ Sbjct: 540 KMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQT----AGREYTL-SGSYTF 594 >3FHH-A nrPDB Length = 640 Score = 69.7 bits (169), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 44/139 (31%), Positives = 76/139 (54%), Gaps = 20/139 (14%) Query: 34 DTIVVTA---AEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGN 90 +T+ VTA A + +AP + ++ +N A + ++R +PG+ L G R N Sbjct: 2 ETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTG----RTN 57 Query: 91 NRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDT-RGDTSWVPPEMIERIEVLRG 149 + I++RG L+L+DG +RQG DT + +++ P +I+R+E++RG Sbjct: 58 GQDINMRGYDHRGVLVLVDG--------IRQG----TDTGHLNGTFLDPALIKRVEIVRG 105 Query: 150 PAAARYGNGAAGGVVNIIT 168 P+A YG+GA GGV++ T Sbjct: 106 PSALLYGSGALGGVISYDT 124 >4EPA-A nrPDB Length = 655 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 51/195 (26%), Positives = 93/195 (47%), Gaps = 39/195 (20%) Query: 33 DDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDV-----SKIIRTMPGVNL--TGN--- 82 + T+VVTA++Q+ ++ + +++ + P D K+ R +PG+N+ +GN Sbjct: 11 ESTLVVTASKQSSRSASANNVSS-TVVSAPELSDAGVTASDKLPRVLPGLNIENSGNMLF 69 Query: 83 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE 142 ST RG + D P TL +DG P S N+++ ++ Sbjct: 70 STISLRGVSSAQDF--YNPAVTL-YVDGVPQLSTNTIQA----------------LTDVQ 110 Query: 143 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT 202 +E+LRGP YG A GG++NI+T++ G + ++ + + R+ F+L+ Sbjct: 111 SVELLRGPQGTLYGKSAQGGIINIVTQQPDSTPRGYIEGGVSSRD------SYRSKFNLS 164 Query: 203 GPLGDEFSFRLYGNL 217 GP+ D LYG++ Sbjct: 165 GPIQDGL---LYGSV 176 Score = 37.0 bits (84), Expect = 0.036, Method: Compositional matrix adjust. Identities = 70/306 (22%), Positives = 116/306 (37%), Gaps = 64/306 (20%) Query: 426 YSKAEIFSLFAENNMELTDSTIVTPGLRFDHH--------SIVGNNWSPA---------- 467 Y+ AE + +++ LTD + G+RF H S++GN + Sbjct: 356 YTTAETLAAYSDLTWHLTDRFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLG 415 Query: 468 -LNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKA 526 L+ L DD+ + +A+ YK PS Y P L +K A Sbjct: 416 QLSAGYMLTDDWRVYTRVAQGYK-PSGYNIVPTAGLDAK-----------------PFVA 457 Query: 527 ETSINKEIGLEFK-RDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVV 585 E SIN E+G ++ D L T++ + ++ +G V + N KA Sbjct: 458 EKSINYELGTRYETADVTLQAATFYTHTKDMQLYSGPVR---------MQTLSNAGKADA 508 Query: 586 EGLEGSLNVPVSETVMWTNNITYMLKSENKTT-----GDRLSIIPEYTLNSTLSWQARED 640 G+E + W N +++SE G+R+ +P Y S+++ Sbjct: 509 TGVELEAKWRFAPGWSWDINGN-VIRSEFTNDSELYHGNRVPFVPRYGAGSSVN------ 561 Query: 641 LSMQTTFTWYGKQQPK-KYNYKGQPAV-GPETKEISPYSIVGLSATWDVTKNVSLTGGVD 698 T YG P+ N G G Y+ + S W T+ ++++ VD Sbjct: 562 ---GVIDTRYGALMPRLAVNLVGPHYFDGDNQLRQGTYATLDSSLGWQATERMNISVYVD 618 Query: 699 NLFDKR 704 NLFD+R Sbjct: 619 NLFDRR 624 >1FCP-A nrPDB Length = 705 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 32/151 (21%) Query: 26 TDTPVSH--DDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNS 83 TDTP+ VVTA E L P + V + + PGV++ Sbjct: 21 TDTPIQKVPQSISVVTAEEMALHQP----------------KSVKEALSYTPGVSV---G 61 Query: 84 TSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIER 143 T G + IRG E S+N+ G + + + D + + P M+ER Sbjct: 62 TRGASNTYDHLIIRGFAAEG----------QSQNNYLNGLKLQGNFYND-AVIDPYMLER 110 Query: 144 IEVLRGPAAARYGNGAAGGVVNIITKKGSGE 174 E++RGP + YG + GG++N+++K+ + E Sbjct: 111 AEIMRGPVSVLYGKSSPGGLLNMVSKRPTTE 141 >5FOK-A nrPDB Length = 730 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 50/178 (28%), Positives = 74/178 (41%), Gaps = 28/178 (15%) Query: 45 LQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENT 104 L P T+ ++ K+ A ++ +RT PG+ G G +R IRG E+ Sbjct: 47 LDTPKTVTVIPQQVIKDTGALTLADALRTTPGITF-GAGEGGNPAGDRPF-IRGFNAESD 104 Query: 105 LILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVV 164 L G RD T V +E+IEV +GP +A G G+ GG + Sbjct: 105 TFL----------------DGMRDVASQTREV--FNVEQIEVSKGPGSAYTGAGSTGGSL 146 Query: 165 NIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQA 222 N+I+K D + +A T+RT + +GD +FRL NL K A Sbjct: 147 NLISKT------AKQDNFTDAGFTWGSDQTRRTTLDVNRMIGDNAAFRL--NLMKHDA 196 Score = 32.7 bits (73), Expect = 0.61, Method: Compositional matrix adjust. Identities = 67/274 (24%), Positives = 102/274 (37%), Gaps = 50/274 (18%) Query: 488 YKAPSLYQTNPN---YILYSKGQGCYASAGG----CYLQGNDDLKAETSINKEIGLE--F 538 Y+ +Y+ PN Y+ +S GG GN+ L E + N E+G + F Sbjct: 481 YQTGLVYKPAPNGSIYLAWSTSSNPTGETGGEGQADISVGNNGLDPERNRNLELGTKWAF 540 Query: 539 KRDGWLAGVTWFRNDYRN-KIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVS 597 D FR D N ++ + V+ Q G + V+G+E N ++ Sbjct: 541 FDDALSLNAALFRTDKTNARVASPDVSTLQVLDG----------EQRVQGVELGFNGKLT 590 Query: 598 ETVMWTNNITYMLKSENKTT--GDRLSIIPEYTLNSTLSWQAREDLSMQTT---FTWYGK 652 E TY+ K+T D + +P+ N+ W + L T T+ K Sbjct: 591 EKWKVFGGYTYLDSEIRKSTVKSDEGNKMPQTAQNNFTLWTTYDLLQNFTIGGGTTYVDK 650 Query: 653 QQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQ 712 Q N + I Y A++ V+KNV L V NL DKR + Sbjct: 651 QYGNTAN----------STYIPSYWRYDAMASYKVSKNVDLQLNVQNLTDKRYF------ 694 Query: 713 TTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 746 D + ++A PGRT + VN HF Sbjct: 695 ---DQVYSTHMAHVA------PGRTALLGVNFHF 719 >3QLB-A nrPDB Length = 748 Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 52/177 (29%), Positives = 82/177 (46%), Gaps = 45/177 (25%) Query: 50 VSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILID 109 +S IT D++ V + V++ +R GV + S QR + + IRG T +L D Sbjct: 105 ISVITRDQMDAQQV-QSVNEALRYTAGVQANTTAAS-QRFDT--LSIRGFD-VTTGMLRD 159 Query: 110 GKPVSSRNSVRQGWRGERDTRGDTSWVPPEM----IERIEVLRGPAAARYGNGAAGGVVN 165 G +G+T+ P++ +ERI+VL+GPA+ +G + GGVVN Sbjct: 160 G------------------LKGNTAQAWPKVEAYGLERIDVLKGPASVLFGQNSPGGVVN 201 Query: 166 IITKKGSGEWHGSWDAYFNAPEHKEE---GATKRT--NFSLTGPLGDE--FSFRLYG 215 I+K+ + P H+ + G+ R F +GPL DE F +RL G Sbjct: 202 QISKRP-----------LDKPFHEVQIQGGSFDRAQGQFDFSGPLDDEGQFLYRLVG 247 >6BPM-C nrPDB Length = 727 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 45/159 (28%), Positives = 73/159 (45%), Gaps = 44/159 (27%) Query: 33 DDTIVVTAAEQNLQAPGVS----------------TITADEIRKNPVARDVSKIIRTMPG 76 DDT+VV A+ +L AP S T+ ++++ K+ A +++ ++ +PG Sbjct: 8 DDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPG 67 Query: 77 VNL-----TGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRG 131 V GNST+G I +RG N+ I IDG +R RDT Sbjct: 68 VGAFFAGENGNSTTGD-----AIYMRGADTSNS-IYIDG--------IRDIGSVSRDTFN 113 Query: 132 DTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKK 170 E++EV++GP+ YG A G +N+I+K+ Sbjct: 114 ---------TEQVEVIKGPSGTDYGRSAPTGSINMISKQ 143 >5FQ8-B nrPDB Length = 984 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 50/176 (28%), Positives = 87/176 (49%), Gaps = 20/176 (11%) Query: 34 DTIVVTAA--EQNLQAPG--VSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRG 89 D +VVTA +++ +A G +++ ++I ++ + +S + + GV ++ STS G Sbjct: 24 DEVVVTAMGIKRSEKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQIS--STSSDPG 81 Query: 90 NNRQIDIRGM----GPENTLILIDGKPVSSRNSVR-QGWRGERDTRGDTSWVPPEMIERI 144 + + IRG+ G L ++DG P+++ G D + + P+ + + Sbjct: 82 ASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDDVANM 141 Query: 145 EVLRGPAA-ARYGNGAAGGVVNIITK-----KGSG-EWHG--SWDAYFNAPEHKEE 191 +L+G AA A YG+ AA GVV I TK KG G E++G W PE + E Sbjct: 142 TILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPEFQNE 197 >1KMO-A nrPDB Length = 774 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 19/123 (15%) Query: 56 DEIRKNPVARD----VSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE---NTLILI 108 D IR+ A+ + +++ +PGV+ N+ +G IRG+ P + +L+ Sbjct: 138 DVIRREDFAKTGATTMREVLNRIPGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLM 197 Query: 109 DGKPVSSRNSVRQGWRGERDTRGDTSWVPPEM--IERIEVLRGPAAARYGNGAAGGVVNI 166 DG PV + S P + ++ I+V+RG A RYG + GGVVN Sbjct: 198 DGIPVPFAPY----------GQPQLSLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNF 247 Query: 167 ITK 169 +T+ Sbjct: 248 VTR 250 Score = 32.3 bits (72), Expect = 0.76, Method: Compositional matrix adjust. Identities = 27/87 (31%), Positives = 43/87 (49%), Gaps = 14/87 (16%) Query: 407 TGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDH------HSIV 460 T T++G G S DR S E + + ++ +++ + TI TPG+RF+H ++I Sbjct: 455 TATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTI-TPGMRFEHIESYQNNAIT 513 Query: 461 G-------NNWSPALNISQGLGDDFTL 480 G N PALN+ L D + L Sbjct: 514 GTHEEVSYNAPLPALNVLYHLTDSWNL 540 >6FOK-A nrPDB Length = 723 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 14/85 (16%) Query: 666 VGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDK----RLWRAGNAQTTGDLAGAN 721 VG + + + + + L+ + VT+NV L+ GVDNLFDK L +AG+ AG Sbjct: 649 VGKDFDKSAGFGVFSLNGAYRVTRNVKLSAGVDNLFDKDYTEHLNKAGD-------AGFG 701 Query: 722 YIAGAGAYTYNEPGRTWYMSVNTHF 746 + A T EPGRT++ V+ F Sbjct: 702 FSANE---TVPEPGRTFWTKVDFSF 723 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 36/159 (22%), Positives = 65/159 (40%), Gaps = 14/159 (8%) Query: 7 SLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPV-AR 65 + A L L + A E H + + Q+ ++ +T + + PV A Sbjct: 37 AFAALCGLALSPSALLAEEHSQHQDHAVELAPSVVTGVAQSSPLTIVTNPKEPRQPVPAS 96 Query: 66 DVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRG 125 D + ++T+PG + N G+N +RGM IL +G + R Sbjct: 97 DGADYLKTIPGFAVIRNG-----GSNGDPVLRGMFGSRLNILTNGGMMLGACPNRMD--- 148 Query: 126 ERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVV 164 TS++ PE +++ V++GP +G GA+ G + Sbjct: 149 -----APTSYISPETYDKLTVIKGPQTVLWGPGASAGTI 182 >5NEC-A nrPDB Length = 741 Score = 42.7 bits (99), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 20/127 (15%) Query: 45 LQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENT 104 L P T+ ++ K+ A + +RT+PG+ +G+ GN P Sbjct: 48 LDTPRSVTVVPKQVIKDTAAVSLQDALRTVPGITFG----AGEGGN----------PTGD 93 Query: 105 LILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVV 164 I G S V G RDT T + +E+IEV +GP +A G G+AGG + Sbjct: 94 RPFIRGFDAQSDTYVD----GVRDTGAQTREI--FNLEQIEVSKGPNSAFGGRGSAGGSL 147 Query: 165 NIITKKG 171 N+++K+ Sbjct: 148 NLVSKQA 154 >5FP1-A nrPDB Length = 718 Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 24/127 (18%) Query: 45 LQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENT 104 L P ++ + ++ ++ ++ +RT+PG+ L G G +R IRG E++ Sbjct: 38 LDTPKSVSVISKQLIEDTKVTTLADALRTVPGITL-GAGEGGNPNGDRPF-IRGYSSESS 95 Query: 105 LILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEM--IERIEVLRGPAAARYGNGAAGG 162 + IDG RNS Q EM +E++EV +G A+A G G+ GG Sbjct: 96 M-YIDG----IRNSTSQN---------------REMFAVEQVEVTKGSASAMGGAGSVGG 135 Query: 163 VVNIITK 169 +N+I+K Sbjct: 136 SINMISK 142 >6E4V-A nrPDB Length = 693 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/139 (28%), Positives = 57/139 (41%), Gaps = 34/139 (24%) Query: 580 VPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENK---------------TTGDRLSII 624 V V +G+E LN +++ T T + +N+ T RL ++ Sbjct: 548 VDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLPVM 607 Query: 625 PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSAT 684 PE T+ ++WQ R T T YG + E Y++V L Sbjct: 608 PELTVGGGVNWQNR---VYTDTVTPYGTFR----------------AEQGSYALVDLFTR 648 Query: 685 WDVTKNVSLTGGVDNLFDK 703 + VTKN SL G V+NLFDK Sbjct: 649 YQVTKNFSLQGNVNNLFDK 667 >6H7F-A nrPDB Length = 706 Score = 39.3 bits (90), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/40 (47%), Positives = 26/40 (65%), Gaps = 3/40 (7%) Query: 138 PEMIERIEVLRGPAAARYG---NGAAGGVVNIITKKGSGE 174 PEM R+EVL+GP+A G G+ GG VN++TK + E Sbjct: 132 PEMFGRVEVLKGPSALLNGMPPAGSVGGTVNLVTKYAADE 171 >4ZGV-A nrPDB Length = 868 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 20/153 (13%) Query: 33 DDTIVVTAAEQNLQAPGVSTITADEIRKNPVAR-DVSKIIRTMPGVNLTGNSTSGQRGNN 91 +DTI+V + + Q+ G+ I A++I+K P V+++++ P V + ++S Sbjct: 53 EDTILVRSTPTS-QSMGMQIINAEQIKKMPTGNGSVTELLKNNPNVQFSNTASSSNIPGE 111 Query: 92 ---RQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGD-------------TSW 135 + G N ++DG ++ + GE + + D + W Sbjct: 112 LAPENVSFHGEKFYNNNFMVDGLSNNNNINPGAN-NGELNQQPDGYSPADLPAGGPQSFW 170 Query: 136 VPPEMIERIEVLRGPAAARYGNGAAGGVVNIIT 168 + E+IE +EV +A+YG+ GGVV+ T Sbjct: 171 INSELIESLEVFDSNISAKYGD-FTGGVVDAKT 202 >2W78-A nrPDB Length = 772 Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 36/154 (23%) Query: 66 DVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRG 125 ++ ++R PG+ ++ T R N RG N DG P ++RN G+ Sbjct: 141 NIDDVMRHTPGITVSAYDT--DRNNYYA---RGFSINN--FQYDGIPSTARNV---GYSA 190 Query: 126 ERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWH-------GS 178 +T D + + +R+EVL+G G G+ G +N+I KK + E+ GS Sbjct: 191 G-NTLSDMA-----IYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGS 244 Query: 179 WDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFR 212 WD Y R+ ++GPL + + R Sbjct: 245 WDNY-------------RSELDVSGPLTESGNVR 265 Score = 28.9 bits (63), Expect = 8.4, Method: Compositional matrix adjust. Identities = 49/230 (21%), Positives = 88/230 (38%), Gaps = 35/230 (15%) Query: 492 SLYQTNPNYILYSKGQGCYASAGGCYL-QGNDDLKAETSINKEIGLEFKR-DGWL-AGVT 548 ++Y N Y +Y+ + Y N L+ + N EIG++ + DG L + Sbjct: 532 AVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLA 591 Query: 549 WFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITY 608 +F N+ E + + Y + + KA +G E ++ ++ W Y Sbjct: 592 YFEIHEENRAEEDALYNSKPTNPAITYAYKGI-KAKTKGYEAEISGELAPG--WQVQAGY 648 Query: 609 MLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFT---------------WYGKQ 653 K +G ++S +W+ ++ LS+ T++ W GK Sbjct: 649 THKIIRDDSGKKVS-----------TWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKS 697 Query: 654 QPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDK 703 YN P E Y +V L A + +T +S + V+N+FDK Sbjct: 698 WQMVYN---NPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDK 744 >1XKH-A nrPDB Length = 687 Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 36/154 (23%) Query: 66 DVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRG 125 ++ ++R PG+ ++ T R N RG N DG P ++RN G+ Sbjct: 56 NIDDVMRHTPGITVSAYDT--DRNNYYA---RGFSINN--FQYDGIPSTARNV---GYSA 105 Query: 126 ERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWH-------GS 178 +T D + + +R+EVL+G G G+ G +N+I KK + E+ GS Sbjct: 106 G-NTLSDMA-----IYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGS 159 Query: 179 WDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFR 212 WD Y R+ ++GPL + + R Sbjct: 160 WDNY-------------RSELDVSGPLTESGNVR 180 Score = 28.9 bits (63), Expect = 9.3, Method: Compositional matrix adjust. Identities = 49/230 (21%), Positives = 88/230 (38%), Gaps = 35/230 (15%) Query: 492 SLYQTNPNYILYSKGQGCYASAGGCYL-QGNDDLKAETSINKEIGLEFKR-DGWL-AGVT 548 ++Y N Y +Y+ + Y N L+ + N EIG++ + DG L + Sbjct: 447 AVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLA 506 Query: 549 WFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITY 608 +F N+ E + + Y + + KA +G E ++ ++ W Y Sbjct: 507 YFEIHEENRAEEDALYNSKPTNPAITYAYKGI-KAKTKGYEAEISGELAPG--WQVQAGY 563 Query: 609 MLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFT---------------WYGKQ 653 K +G ++S +W+ ++ LS+ T++ W GK Sbjct: 564 THKIIRDDSGKKVS-----------TWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKS 612 Query: 654 QPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDK 703 YN P E Y +V L A + +T +S + V+N+FDK Sbjct: 613 WQMVYN---NPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDK 659 >3EFM-A nrPDB Length = 707 Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 654 QPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLW 706 Q + Y P E ++ S Y++V L A +D K +S T V+NLFDK+ + Sbjct: 631 QSRMYQAAASPRGNVEVEQDS-YALVSLMARFDFNKKLSATLNVNNLFDKKYY 682 >3V8X-A nrPDB Length = 904 Score = 33.9 bits (76), Expect = 0.24, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 22/41 (53%) Query: 524 LKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVA 564 + E S NKE G+ FK D +WF N YR+ I GY A Sbjct: 659 IDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEA 699 Score = 32.3 bits (72), Expect = 0.72, Method: Compositional matrix adjust. Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 13/144 (9%) Query: 34 DTIVVTAAEQN------LQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQ 87 DTI V A +Q + G ++D + K V ++ + R PG+ + Sbjct: 27 DTIQVKAKKQKTRRDNEVTGLGKLVKSSDTLSKEQVL-NIRDLTRYDPGIAVVEQG---- 81 Query: 88 RGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERD--TRGDTSWVPPEMIERIE 145 RG + IRGM + +DG + + G R + G + + E ++ +E Sbjct: 82 RGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVE 141 Query: 146 VLRGPAAARYGNGAAGGVVNIITK 169 + +G + G+GA G V TK Sbjct: 142 ISKGSNSVEQGSGALAGSVAFQTK 165 >1XKW-A nrPDB Length = 665 Score = 33.5 bits (75), Expect = 0.39, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 9/61 (14%) Query: 131 GDTSWVPPEM--IERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEW-------HGSWDA 181 G+T+ P +M ER+E+LRG +G G VN++ K+ E+ G WD Sbjct: 86 GNTASSPQDMAIYERVEILRGSNGLLHGTGNPAATVNLVRKRPQREFAASTTLSAGRWDR 145 Query: 182 Y 182 Y Sbjct: 146 Y 146 >4B7O-A nrPDB Length = 745 Score = 32.7 bits (73), Expect = 0.63, Method: Compositional matrix adjust. Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 17/131 (12%) Query: 34 DTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQ 93 DT+ V Q + + I + + A D+ ++++ P ++ G + G ++ Sbjct: 54 DTVTVKGDRQGSKIR--TNIVTLQQKDESTATDMRELLKEEPSIDFGGGN-----GTSQF 106 Query: 94 IDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAA 153 + +RGMG + I +D S+ QG V P +++ + V +G +A Sbjct: 107 LTLRGMGQNSVDIKVDNAYSDSQILYHQG----------RFIVDPALVKVVSVQKGAGSA 156 Query: 154 RYGNGAAGGVV 164 G GA G + Sbjct: 157 SAGIGATNGAI 167 >4AIP-A nrPDB Length = 742 Score = 32.7 bits (73), Expect = 0.65, Method: Compositional matrix adjust. Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 17/131 (12%) Query: 34 DTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQ 93 DT+ V Q + + I + + A D+ ++++ P ++ G + G ++ Sbjct: 54 DTVTVKGDRQGSKIR--TNIVTLQQKDESTATDMRELLKEEPSIDFGGGN-----GTSQF 106 Query: 94 IDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAA 153 + +RGMG + I +D S+ QG V P +++ + V +G +A Sbjct: 107 LTLRGMGQNSVDIKVDNAYSDSQILYHQG----------RFIVDPALVKVVSVQKGAGSA 156 Query: 154 RYGNGAAGGVV 164 G GA G + Sbjct: 157 SAGIGATNGAI 167 >1ICX-A nrPDB Length = 155 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 11/117 (9%) Query: 240 ATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKY 299 +T PA + KD + +V P+QS+E+ G G + + S+ K Sbjct: 11 STVAPAKLYKALTKDSDEIVPKVIEPIQSVEIVEGNGGPGTIKKIIAIHDGHTSFVLHKL 70 Query: 300 G--DETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEK 354 DE N Y NY++ G D + + YE S+I G GG+ GK N K Sbjct: 71 DAIDEANLTY--NYSIIGGEGLDESLEK---ISYE----SKILPGPDGGSIGKINVK 118 >4RDT-A nrPDB Length = 748 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%) Query: 502 LYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEA 560 LY+ G+ A + GN L E S N E+ L ++ D W + +RN + N I A Sbjct: 507 LYAHGKHV---ATNTFEVGNKHLNKERSNNIELALGYEGDRWQYNLALYRNRFGNYIYA 562 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1FEP-A nrPDB 1004 0.0 5M9B-A nrPDB 905 0.0 5FP2-A nrPDB 872 0.0 5FR8-A nrPDB 789 0.0 2HDF-A nrPDB 595 e-170 1NQH-A nrPDB 496 e-140 5FOK-A nrPDB 199 4e-51 3FHH-A nrPDB 182 6e-46 6BPM-C nrPDB 181 8e-46 4EPA-A nrPDB 179 4e-45 5NEC-A nrPDB 172 4e-43 6E4V-A nrPDB 169 6e-42 6FOK-A nrPDB 164 1e-40 1KMO-A nrPDB 163 2e-40 5FP1-A nrPDB 155 9e-38 1FCP-A nrPDB 139 3e-33 3QLB-A nrPDB 132 5e-31 5FQ8-B nrPDB 119 4e-27 Sequences not found previously or not previously below threshold: 2W78-A nrPDB 148 7e-36 1XKH-A nrPDB 146 3e-35 1XKW-A nrPDB 118 9e-27 3EFM-A nrPDB 109 4e-24 4AIP-A nrPDB 99 5e-21 4B7O-A nrPDB 95 2e-19 3V8X-A nrPDB 87 2e-17 6H7F-A nrPDB 84 2e-16 3CSL-A nrPDB 83 6e-16 4RDT-A nrPDB 79 8e-15 3DWO-X nrPDB 38 0.016 5XAO-A nrPDB 36 0.079 6ID1-L nrPDB 35 0.13 1GPE-A nrPDB 33 0.39 6AGQ-A nrPDB 32 0.78 1W9D-M nrPDB 32 0.93 4Q35-A nrPDB 31 2.5 4RHB-A nrPDB 31 2.6 >1FEP-A nrPDB Length = 724 Score = 1004 bits (2594), Expect = 0.0, Method: Composition-based stats. Identities = 724/724 (100%), Positives = 724/724 (100%) Query: 23 QEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGN 82 QEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGN Sbjct: 1 QEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGN 60 Query: 83 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE 142 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE Sbjct: 61 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE 120 Query: 143 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT 202 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT Sbjct: 121 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT 180 Query: 203 GPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWD 262 GPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWD Sbjct: 181 GPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWD 240 Query: 263 FAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNG 322 FAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNG Sbjct: 241 FAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNG 300 Query: 323 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN 382 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN Sbjct: 301 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN 360 Query: 383 QTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMEL 442 QTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMEL Sbjct: 361 QTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMEL 420 Query: 443 TDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYIL 502 TDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYIL Sbjct: 421 TDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYIL 480 Query: 503 YSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGY 562 YSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGY Sbjct: 481 YSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGY 540 Query: 563 VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLS 622 VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLS Sbjct: 541 VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLS 600 Query: 623 IIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS 682 IIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS Sbjct: 601 IIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS 660 Query: 683 ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSV 742 ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSV Sbjct: 661 ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSV 720 Query: 743 NTHF 746 NTHF Sbjct: 721 NTHF 724 >5M9B-A nrPDB Length = 724 Score = 905 bits (2338), Expect = 0.0, Method: Composition-based stats. Identities = 442/734 (60%), Positives = 552/734 (75%), Gaps = 18/734 (2%) Query: 20 AQAQEPTDTPVSH-DDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVN 78 A A + + + + T+V TA E+ QAPGVS ITA++I K P + D+S+IIRTMPGVN Sbjct: 2 AMAGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVN 61 Query: 79 LTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPP 138 LTGNS+SGQRGNNRQIDIRGMGPENTLIL+DGKPVSSRNSVR GWRGERD+RGDT+WVP Sbjct: 62 LTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPA 121 Query: 139 EMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTN 198 + +ERIEV+RGPAAARYGNGAAGGVVNIITK+ E HG+ Y N P+HK EGA++R + Sbjct: 122 DQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMS 181 Query: 199 FSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGV 258 F L GPL + S+R+YGN+ KT +D WDIN GH+S R G A TLPAGREGV NKDI+G+ Sbjct: 182 FGLNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGL 241 Query: 259 VRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGG 318 + W P Q+LE EAG+SRQGN+Y GDTQNTNS++Y + G ETNR+YR+ Y++T G Sbjct: 242 LSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGE 301 Query: 319 WDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPID 378 WD G + + ++QYE TRNSRI EGLAGGTEG F+ F L D+ H EVNLP+ Sbjct: 302 WDFGSSLA-YLQYEKTRNSRINEGLAGGTEGIFDP-NNAGFYTATLRDLTAHGEVNLPLH 359 Query: 379 FLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAEN 438 QTLTLG+EW +Q++ D SSNTQ T GG+I G++ +RS S A IFSLFAE+ Sbjct: 360 LGYEQTLTLGSEWTEQKLDDPSSNTQ---NTEEGGSIPGLAGKNRSSSSSARIFSLFAED 416 Query: 439 NMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNP 498 N+EL T++TPGLR+DHH IVG+NWSP+LN+S L + TLK GIARAYKAP+LYQ NP Sbjct: 417 NIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNP 476 Query: 499 NYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKI 558 +Y+LYS+GQGCY + CYL+GND LKAETS+NKE+G+E+ DG +AG+T+FRNDY+NKI Sbjct: 477 DYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKI 536 Query: 559 EAGYVAVGQNAVG------TDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKS 612 E+G V + G +YQW+NVPKAVVEGLEG+L +P+++ + W+NN+TYML+S Sbjct: 537 ESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQS 596 Query: 613 ENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKE 672 +NK TGD LS+ P YTLNS L WQA +DLS+Q T TWYGKQ+PKKY+Y G G + Sbjct: 597 KNKETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQ 656 Query: 673 ISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYN 732 +SPY+I GL T+ ++KN+SL GVDNLFDKRL+RAGNAQ G I GAGA TYN Sbjct: 657 LSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQ------GVVGIDGAGAATYN 710 Query: 733 EPGRTWYMSVNTHF 746 EPGRT+Y S+ F Sbjct: 711 EPGRTFYTSLTASF 724 >5FP2-A nrPDB Length = 725 Score = 872 bits (2252), Expect = 0.0, Method: Composition-based stats. Identities = 407/726 (56%), Positives = 520/726 (71%), Gaps = 30/726 (4%) Query: 27 DTPVSHDDTIVVTAAEQNL-QAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTS 85 ++ V D +V+ AEQ L QAPGVS ITA++IRK P D+S+IIRTMPGVNLTGNS+S Sbjct: 16 ESVVQLGDEVVLGTAEQELKQAPGVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTGNSSS 75 Query: 86 GQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIE 145 GQRGNNRQIDIRGMGPENTLIL+DGKPVSSRNSVR GWRGERDTRGD++WVPPE +ERIE Sbjct: 76 GQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDTRGDSNWVPPEEVERIE 135 Query: 146 VLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPL 205 VLRGPAAARYG+GAAGGVVNIITK+ + GS + N PE ++GAT+R NFSL+GPL Sbjct: 136 VLRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPL 195 Query: 206 GDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAP 265 + SFR YG+ +KT +D DIN GH + T AGREGV N+D++G++ W P Sbjct: 196 TEALSFRAYGSANKTDSDDTDINLGHTVNPSRTV-----AGREGVRNRDLSGMLSWQVTP 250 Query: 266 LQSLELEAGYSRQGNLYAGDTQNTNSDSYTRS--KYGDETNRLYRQNYALTWNGGWDNGV 323 Q ++ EAG+SRQGN+YAGDTQN N + T+ G ETNR+YR+NYA+T NG W G Sbjct: 251 DQVVDFEAGFSRQGNIYAGDTQNNNGTANTQGLADDGAETNRMYRENYAITHNGTWSFG- 309 Query: 324 TTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQ 383 T+ QY+ TRN+R+ EGLAG EG+ A + F L++ L E+NLP+ L Q Sbjct: 310 TSRFVAQYDSTRNNRLEEGLAGSVEGQIG--ADRSFSASKLENYRLSGELNLPLHALFEQ 367 Query: 384 TLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELT 443 LT+G EWN++ + D SS Q G+++ + RSP SKAEI +L+ E+N+EL Sbjct: 368 VLTVGAEWNKETLNDPSSLKQGFVGSDSLPGTPAAGS--RSPKSKAEIRALYVEDNIELR 425 Query: 444 DSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILY 503 T++TPGLR D HS G NWSP+LN SQ LG+ FT+K GIARA+KAP+LYQ+NPNY+LY Sbjct: 426 PGTMLTPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAPNLYQSNPNYLLY 485 Query: 504 SKGQGCY--ASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAG 561 ++G GC S+GGCYL GN++L AETS+NKE+G+EF+RDGW+AG+T+FRNDY+NKI A Sbjct: 486 TRGNGCPIQTSSGGCYLVGNENLDAETSVNKELGIEFRRDGWVAGLTYFRNDYKNKIVAP 545 Query: 562 YVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRL 621 +GQ G ++ QW N KAVVEGLEG+L VP+ E + W+ N+TYML+S++K TG+ L Sbjct: 546 LDVMGQTGTGNNILQWSNAKKAVVEGLEGNLLVPLHEDLSWSTNLTYMLQSKDKDTGNPL 605 Query: 622 SIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKY-NYKGQPAVGPETKEISPYSIVG 680 S+IPEYTLNSTL WQA E LS Q T T YG+Q+P K+ + P V KE+ Y I G Sbjct: 606 SVIPEYTLNSTLDWQASERLSTQLTSTIYGRQEPPKHGTSRNTPVV--SRKEVGTYGIWG 663 Query: 681 LSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM 740 +SA + ++N+S+ GGV NLFDKRL+R GN+ AGA TYNEPGR +Y+ Sbjct: 664 VSAGYTFSENLSVRGGVSNLFDKRLYRQGNS------------FDAGAATYNEPGRAYYV 711 Query: 741 SVNTHF 746 S+ T F Sbjct: 712 SMTTSF 717 >5FR8-A nrPDB Length = 733 Score = 789 bits (2037), Expect = 0.0, Method: Composition-based stats. Identities = 347/756 (45%), Positives = 472/756 (62%), Gaps = 62/756 (8%) Query: 21 QAQEPTDTPVS--HDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVN 78 QA++ + P +TI VTA EQ Q+ GVS IT +++ K PV D+S +R MPGVN Sbjct: 10 QAEQTLEKPAEPVKLETIFVTAEEQVKQSLGVSVITKEDLEKLPVRNDISDYVRRMPGVN 69 Query: 79 LTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPP 138 LTGNS +GQRGNNRQIDIRGMGPENTLIL+DGKP++SRNSVR GW+GERDTRGD++WVP Sbjct: 70 LTGNSATGQRGNNRQIDIRGMGPENTLILVDGKPINSRNSVRYGWKGERDTRGDSNWVPA 129 Query: 139 EMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTN 198 E IE IEVLRGPAAARYG+GAAGGVVNIITKK + E HGS + Y + PE +EG++ R Sbjct: 130 EAIESIEVLRGPAAARYGSGAAGGVVNIITKKVTNETHGSVEFYTSQPEDSKEGSSNRVG 189 Query: 199 FSLTGPL-GDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDING 257 F+++GPL D S+RLYGN +KT+AD DIN+ S AGREGV NKDI+G Sbjct: 190 FNVSGPLIKDVLSYRLYGNYNKTEADDVDINKSIGSTA---------AGREGVKNKDISG 240 Query: 258 VVRWDFAPLQSLELEAGYSRQGNLYAGDTQ---NTNSDSYTRSKYGDETNRLYRQNYALT 314 + W Q++ L+ S+QGN+Y+GD+Q N +D+ G ETN +YR +YALT Sbjct: 241 RLAWQATDQQTVLLDISSSKQGNIYSGDSQLNANAEADAILSQLIGKETNTMYRDSYALT 300 Query: 315 WNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVN 374 G W G + QY+ T N R+PEGLAG EGK N D L+ + + E N Sbjct: 301 HEGDWSWG-KSKLVAQYDKTHNKRLPEGLAGSVEGKIN--NLDDKATSRLETLRFNGEAN 357 Query: 375 LPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSL 434 +P ++ + Q LT+GTEW + R KD S TQ + +G D ++ DRS ++ I S Sbjct: 358 IPFEYYLPQVLTVGTEWVEDRFKDNVSTTQGKDSSGSGYG-DQLAKGDRSKM-ESRIASA 415 Query: 435 FAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLY 494 + E+N+++TDST V GLRFD HS G+NWSP+LNI+Q L D FTLK G+A+AYKAP++Y Sbjct: 416 YIEDNLKVTDSTDVVLGLRFDDHSKSGSNWSPSLNITQKLNDYFTLKGGVAKAYKAPNMY 475 Query: 495 QTNPNYILYSKGQGCYAS-AGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRND 553 Q Y+L + G GC A+ C LQGN DLK ETS+NKE+G++F++D A +TWFRND Sbjct: 476 QNAEGYLLSTNGNGCPANIESRCLLQGNGDLKPETSVNKELGIQFQKDIVNASLTWFRND 535 Query: 554 YRNKIEAGYVAVGQNAVGT-------------DLYQWDNVPKAVVEGLEGSLNVPVSETV 600 Y++KI AG VG + ++ +W+N PKA+++G EGSL + + + Sbjct: 536 YKDKIVAGTHVVGTVDGSSTNANTGAVTNTKWNILRWENTPKALIQGFEGSLGLDFGD-I 594 Query: 601 MWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNY 660 WTNN TYM+ S++K TG+ LS++P YT+NS + + L + FT YG+Q+ +++ Sbjct: 595 RWTNNFTYMMDSKDKQTGNPLSLVPIYTINSIFDYDITDQLDVNFVFTQYGRQKSRQFAE 654 Query: 661 K----------GQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGN 710 A+ P T + YS G++ + + +S GV NLFDK++ R N Sbjct: 655 NRLESGIGSGGANSALKPSTVK--SYSTAGINVGYKFSDQISTRVGVSNLFDKQILRDSN 712 Query: 711 AQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 746 + + TYNEPGR +Y S+ F Sbjct: 713 SISQ---------------TYNEPGRAYYASLKYSF 733 >2HDF-A nrPDB Length = 639 Score = 595 bits (1534), Expect = e-170, Method: Composition-based stats. Identities = 234/745 (31%), Positives = 341/745 (45%), Gaps = 142/745 (19%) Query: 33 DDTIVVTAA--EQNL-QAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRG 89 +T+VVTA+ EQNL AP ++ E + +++ +++ +PGV LT Sbjct: 6 GETMVVTASSVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEG-----D 60 Query: 90 NNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRG 149 N + + IRG+ TLIL+DGK V+SRN+V R D +W+P + IERIEV+RG Sbjct: 61 NRKGVSIRGLDSSYTLILVDGKRVNSRNAVF------RHNDFDLNWIPVDSIERIEVVRG 114 Query: 150 PAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDE- 208 P ++ YG+ A GGVVNIITKK +W G+ EH++ G T F +GPL D Sbjct: 115 PMSSLYGSDALGGVVNIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGV 174 Query: 209 FSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQS 268 + YG+L K + D + T T EG ++D G V + + P Q+ Sbjct: 175 LGMKAYGSLAKREKD--------DPQNSTTTDTGETPRIEGFSSRD--GNVEFAWTPNQN 224 Query: 269 LELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNW 328 + AG Y D Q+ +SDS + NRL RQNY+++ NG WD G TS Sbjct: 225 HDFTAG-------YGFDRQDRDSDSLDK-------NRLERQNYSVSHNGRWDYG--TSEL 268 Query: 329 VQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLG 388 Y ++ P G + +E T D + LP+ +NQ LT+G Sbjct: 269 KYYGEKVENKNP----GNSSPITSESNTVD------------GKYTLPLT-AINQFLTVG 311 Query: 389 TEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIV 448 E +M D + T S + A ++LF E+ + + + Sbjct: 312 GEMRHDKMSDAVNLTGG-----------------TSSKTSASQYALFVEDEWRIFEPLAL 354 Query: 449 TPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG 508 T G+R D H G +WSP + D T+K G A A+KAPSL Q +P++ S Sbjct: 355 TTGVRMDDHETYGEHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNS---- 410 Query: 509 CYASAGGCYLQGNDDLKAETSINKEIGLEFK-RDGWLAG----VTWFRNDYRNKIE---- 559 G C + G+ DLK ETS + E+GL + +GWL G VT FRND +++I Sbjct: 411 ---CRGACKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRT 467 Query: 560 ------AGY-----VAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITY 608 GY G N ++ + NV KA ++G+E L +P ++ + N TY Sbjct: 468 SDVNAAPGYQNFVGFETGANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTY 527 Query: 609 -----MLKSENKTTGDRLSIIPEYTLNSTLSWQ--AREDLSMQTTFTWYGKQQPKKYNYK 661 + ENK LS +P +T N TL W+ A ED SM + + G+++ Sbjct: 528 NDGRDVSNGENK----PLSDLPFHTANGTLDWKPLALEDWSMYMSGHYTGQKR------- 576 Query: 662 GQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGAN 721 A K Y+I A W VTK+V L GV NL DK L R Sbjct: 577 ---ADSATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSR-------------- 619 Query: 722 YIAGAGAYTYNEPGRTWYMSVNTHF 746 Y+YNE GR ++M+V+ F Sbjct: 620 -----DDYSYNEDGRRYFMAVDYRF 639 >1NQH-A nrPDB Length = 594 Score = 496 bits (1277), Expect = e-140, Method: Composition-based stats. Identities = 163/713 (22%), Positives = 269/713 (37%), Gaps = 139/713 (19%) Query: 34 DTIVVTA-----AEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQR 88 DT+VVTA + AP + +T +I + + V+ ++R +PGV++T N SGQ Sbjct: 6 DTLVVTANRFEQPRSTVLAP-TTVVTRQDIDRWQ-STSVNDVLRRLPGVDITQNGGSGQL 63 Query: 89 GNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLR 148 I IRG + L+LIDG ++ D S P +++R+E +R Sbjct: 64 ---SSIFIRGTNASHVLVLIDGVRLNLAGV---------SGSADLSQFPIALVQRVEYIR 111 Query: 149 GPAAARYGNGAAGGVVNIITKK--GSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT--GP 204 GP +A YG+ A GGVVNIIT + E W G+ N+ ++ Sbjct: 112 GPRSAVYGSDAIGGVVNIITTRDEPGTEISAGW------------GSNSYQNYDVSTQQQ 159 Query: 205 LGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFA 264 LGD+ L G+ T G+ G T +G ++K + G + +F Sbjct: 160 LGDKTRVTLLGDYAHT--------HGYDVVAYGNTGTQAQTDNDGFLSKTLYGALEHNFT 211 Query: 265 PLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNY--ALTWNGGWDNG 322 S G+ R Y D + Y+ +T +LY Q++ L +NG Sbjct: 212 DAWS-----GFVRG---YGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRYNG---EL 260 Query: 323 VTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVN 382 + + Y H+++ G+++ AT D M V + +V Sbjct: 261 IKSQLITSYSHSKDYNYDPHY-----GRYDSSATL--------DEMKQYTVQWANNVIVG 307 Query: 383 Q-TLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNME 441 ++ G +W +Q T TG DG + Y ++ Sbjct: 308 HGSIGAGVDWQKQ-----------TTTPGTGYVEDGYDQRNTGIYLTG----------LQ 346 Query: 442 LTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYI 501 R D +S G + + + + + +YKAP+L Q Sbjct: 347 QVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQL----- 401 Query: 502 LYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAG 561 G Y GN +L E S E E G AGV W + YRN + Sbjct: 402 -----YGFY---------GNPNLDPEKSKQWEGAFE----GLTAGVNWRISGYRNDVSDL 443 Query: 562 YVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNV---PVSETVMWTNNITYMLKSENKTTG 618 ++ N KA ++G+E + N P++ TV + + + N T Sbjct: 444 IDYDDHT------LKYYNEGKARIKGVEATANFDTGPLTHTVSYD-----YVDARNAITD 492 Query: 619 DRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSI 678 L + + L WQ D T+ + G + K Y+ + +T ++ S+ Sbjct: 493 TPLLRRAKQQVKYQLDWQLY-DFDWGITYQYLGTRYDKDYS-----SYPYQTVKMGGVSL 546 Query: 679 VGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTY 731 L+ + VT ++++ G + NLFDK QT AG Y +G+YT+ Sbjct: 547 WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQT----AGREYTL-SGSYTF 594 >5FOK-A nrPDB Length = 730 Score = 199 bits (505), Expect = 4e-51, Method: Composition-based stats. Identities = 151/763 (19%), Positives = 251/763 (32%), Gaps = 105/763 (13%) Query: 22 AQEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTG 81 ++ +T + D + L P T+ ++ K+ A ++ +RT PG+ G Sbjct: 24 GEQQDETTYNVDRSASKKYTAPLLDTPKTVTVIPQQVIKDTGALTLADALRTTPGITF-G 82 Query: 82 NSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMI 141 G +R IRG E+ L G RD T V + Sbjct: 83 AGEGGNPAGDRPF-IRGFNAESDTFL----------------DGMRDVASQTREV--FNV 123 Query: 142 ERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSL 201 E+IEV +GP +A G G+ GG +N+I+K D + +A T+RT + Sbjct: 124 EQIEVSKGPGSAYTGAGSTGGSLNLISKT------AKQDNFTDAGFTWGSDQTRRTTLDV 177 Query: 202 TGPLGDEFSFRLYGNLDKTQAD----AWDINQGHQSARAGTYATTLPAGRE----GVINK 253 +GD +FRL NL K A A T+ P + Sbjct: 178 NRMIGDNAAFRL--NLMKHDAHVAGRDEVSVSRWGVAPTVTFGFDTPTRATLSYYHLSTD 235 Query: 254 DI--NGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDE--------- 302 D+ G+ + ++ + + N Y ++ + + E Sbjct: 236 DMPDYGLPLTNVNRSKANPSKPASVDRDNFYGLKDRDYRKSTTDSGTFRIEHDLNDNLTL 295 Query: 303 --TNRLYRQNYA-LTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDF 359 + RL R + N G + +V + +G T+ K N + T Sbjct: 296 SNSTRLVRTTLDYIVSNPDDSRGNVANGYVYRSAKSRNSTSKGWVNQTDLKANFE-TGFI 354 Query: 360 VDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTN---TGGAID 416 + + E + + G N + + + TG D Sbjct: 355 KHTLVTGLEFSYEDVHNRPYAITSGGGAGNTCNARLLASGDCTSLNRPTPGDNWTGSITD 414 Query: 417 GVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDH-------HSIVGNNWSPALN 469 G++ TD + A + + ++L++ + GLR+D + G N Sbjct: 415 GLAYTDTDTKTSA----AYVFDTLKLSEQWELNLGLRYDDFDTKSSGYQTAGRNGPAGYF 470 Query: 470 ISQGLGDDFTLKMGIARAYK-APSLYQTNPNYILYSKGQGCYASAGGCYL-QGNDDLKAE 527 + + + G+ YK AP+ + S G G + GN+ L E Sbjct: 471 KRENNSHFWNYQTGL--VYKPAPN-GSIYLAWSTSSNPTGETGGEGQADISVGNNGLDPE 527 Query: 528 TSINKEIGLE--FKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVV 585 + N E+G + F D FR D N A + + V Sbjct: 528 RNRNLELGTKWAFFDDALSLNAALFRTDKTNARVASPDV-----STLQVLD----GEQRV 578 Query: 586 EGLEGSLNVPVSETVMWTNNITYMLKSENKTT--GDRLSIIPEYTLNSTLSWQAREDLSM 643 +G+E N ++E TY+ K+T D + +P+ N+ W DL Sbjct: 579 QGVELGFNGKLTEKWKVFGGYTYLDSEIRKSTVKSDEGNKMPQTAQNNFTLWTTY-DLLQ 637 Query: 644 QTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDK 703 T K+Y P Y A++ V+KNV L V NL DK Sbjct: 638 NFTIGGGTTYVDKQYGNTANSTYIPS------YWRYDAMASYKVSKNVDLQLNVQNLTDK 691 Query: 704 RLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 746 R + + +A PGRT + VN HF Sbjct: 692 RYFDQVYSTHMAHVA---------------PGRTALLGVNFHF 719 >3FHH-A nrPDB Length = 640 Score = 182 bits (461), Expect = 6e-46, Method: Composition-based stats. Identities = 134/700 (19%), Positives = 252/700 (36%), Gaps = 108/700 (15%) Query: 34 DTIVVTA---AEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGN 90 +T+ VTA A + +AP + ++ +N A + ++R +PG+ L G R N Sbjct: 2 ETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTG----RTN 57 Query: 91 NRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGP 150 + I++RG L+L+DG + + +++ P +I+R+E++RGP Sbjct: 58 GQDINMRGYDHRGVLVLVDGIRQGTDT-----------GHLNGTFLDPALIKRVEIVRGP 106 Query: 151 AAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFS 210 +A YG+GA GGV++ T +A + +EG + TG GD Sbjct: 107 SALLYGSGALGGVISYDT--------------VDAKDLLQEGQSSGFRVFGTGGTGDHSL 152 Query: 211 FRLYGNLDKTQA-DAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSL 269 +T+ D E + N G W QSL Sbjct: 153 GLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKG--TWQIDSAQSL 210 Query: 270 ELEAGYSRQGNLYAGDTQNTNS-DSYTRSKYGDETNRLYRQ---NYALTWNGGWDNGVTT 325 +G R N A + +N + ++ S + + + R +Y L G D Sbjct: 211 ---SGLVRYYNNDAREPKNPQTVEASESSNPMVDRSTIQRDAQLSYKLAPQGN-DWLNAD 266 Query: 326 SNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTL 385 + E N++ G+ G++ E+ T+ L + L D + L Sbjct: 267 AKIYWSEVRINAQNT-----GSSGEYREQITKGA--------RLENRSTLFADSFASHLL 313 Query: 386 TLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTD- 444 T G E+ +Q + G TG P +K + S + ++ + L D Sbjct: 314 TYGGEYYRQEQGSHHHHHHHPGGATTGF-----------PQAKIDFSSGWLQDEITLRDL 362 Query: 445 STIVTPGLRFDHH--------SIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQT 496 + G R+D + + + WS ++ + L A+A++AP++ + Sbjct: 363 PITLLGGTRYDSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEM 422 Query: 497 NPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAG-------VTW 549 + +S G+ Y + Y N +L+ ET+ +E G + D + ++ Sbjct: 423 YNDSKHFSIGR-FYTN----YWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASY 477 Query: 550 FRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYM 609 F ++ I + NVP A + G + ++ Sbjct: 478 FDTKAKDYISTTVDFAAATTMS------YNVPNAKIWGWDVMTKYT-TDLFSLDVAYNR- 529 Query: 610 LKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPE 669 + ++ TG+ +S I T+ STL+ + W G + + Sbjct: 530 TRGKDTDTGEYISSINPDTVTSTLNIPIAHS---GFSVGWVGTFADR------STHISSS 580 Query: 670 TKEISPYSIVGLSATW---DVTKNVSLTGGVDNLFDKRLW 706 + Y + ++ K ++ T + N FDK W Sbjct: 581 YSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYW 620 >6BPM-C nrPDB Length = 727 Score = 181 bits (459), Expect = 8e-46, Method: Composition-based stats. Identities = 139/783 (17%), Positives = 261/783 (33%), Gaps = 132/783 (16%) Query: 33 DDTIVVTAAEQNLQAPGVS----------------TITADEIRKNPVARDVSKIIRTMPG 76 DDT+VV A+ +L AP S T+ ++++ K+ A +++ ++ +PG Sbjct: 8 DDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPG 67 Query: 77 VNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWV 136 V +G I +RG N+ I IDG +R RDT Sbjct: 68 VGAFFAGENGNSTTGDAIYMRGADTSNS-IYIDG--------IRDIGSVSRDTFN----- 113 Query: 137 PPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKR 196 E++EV++GP+ YG A G +N+I+K+ D+ +A +R Sbjct: 114 ----TEQVEVIKGPSGTDYGRSAPTGSINMISKQPRN------DSGIDASASIGSAWFRR 163 Query: 197 TNFSLTGPLGDEFSFRL--YGNLDKTQADAWDINQGHQSARAGTYATTLPAG-----REG 249 + +GD + RL G N+ + A + + Sbjct: 164 GTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVAFGLGTANRLYLNYLHV 223 Query: 250 VINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQ 309 + +G + P S AG + + DT N +T + Sbjct: 224 TQHNTPDGGIPTIGLPGYSAP-SAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATM--- 279 Query: 310 NYALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFV-------DI 362 + ++ T N ++ + + + GG + + Sbjct: 280 ----RFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTK 335 Query: 363 DLDDVMLHSEVNLPIDFL---VNQTLTLGTEWNQQRMKDLSSNTQALTG-----TNTGGA 414 D+ + +L ++ NL F + ++ G E+ ++ + N L ++ Sbjct: 336 DVSNKILTNQTNLTSTFYTGSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIH 395 Query: 415 IDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGL 474 G++ + + + F+++A + +++T + G+R D++ ++ + +G Sbjct: 396 PGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGA 455 Query: 475 -------------GDDFTLKMGIARAYKAPSLYQTNPNYILYSK----------GQGCYA 511 T K G +KA +LY N +Y A Sbjct: 456 ITCPTGVAKGSPVTTVDTAKSGNLMNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALA 515 Query: 512 SAGGCYLQGNDDLKAETSINKEIGLEFK--RDGWLAGVTWFRNDYRNKIEAGYVAVGQNA 569 +G D K + + EIG +++ L FR D N++E Sbjct: 516 QSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVE---------- 565 Query: 570 VGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITY----MLKSEN--KTTGDRLSI 623 D + K VEG E S+ ++ T + ++ + L Sbjct: 566 -QNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPY 624 Query: 624 IPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSA 683 PE+ +QA +D+S+ + G G PA Y + Sbjct: 625 TPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTE------GYWVADAKL 678 Query: 684 TWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVN 743 + V +N+ V NLFD + N G EP RT+ ++ N Sbjct: 679 GYRVNRNLDFQLNVYNLFDTDYVASINKSGYRYHPG-------------EP-RTFLLTAN 724 Query: 744 THF 746 HF Sbjct: 725 MHF 727 >4EPA-A nrPDB Length = 655 Score = 179 bits (453), Expect = 4e-45, Method: Composition-based stats. Identities = 144/749 (19%), Positives = 256/749 (34%), Gaps = 148/749 (19%) Query: 27 DTPVSHDDTIVVTAAEQNLQAPGVSTITADEI----RKNPVARDVSKIIRTMPGVNLTGN 82 T + T+VVTA++Q+ ++ + +++ + + K+ R +PG+N+ + Sbjct: 5 QTSQQDESTLVVTASKQSSRSASANNVSSTVVSAPELSDAGVTASDKLPRVLPGLNIENS 64 Query: 83 S-----TSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVP 137 T RG + D P TL +DG P S N+++ Sbjct: 65 GNMLFSTISLRGVSSAQDF--YNPAVTL-YVDGVPQLSTNTIQA---------------- 105 Query: 138 PEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRT 197 ++ +E+LRGP YG A GG++NI+T++ G + ++ + + R+ Sbjct: 106 LTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDSTPRGYIEGGVSSRD------SYRS 159 Query: 198 NFSLTGPLGDEFSFRLYGNLD-KTQADAWD-INQGHQSARAGTYATTLPAGREGVINKDI 255 F+L+GP+ D LYG++ Q D D IN S G ++ Sbjct: 160 KFNLSGPIQDGL---LYGSVTLLRQVDDGDMINPATGSDDLGGTRASI------------ 204 Query: 256 NGVVRWDFAP-LQSLELEAGYSRQGNLYAGDTQNTNSD------SYTRSKYGDETNR-LY 307 G V+ AP Q E+ SR+ D +D S + R Sbjct: 205 -GNVKLRLAPDDQPWEMGFAASRECTRATQDAYVGWNDIKGRKLSISDGSPDPYMRRCTD 263 Query: 308 RQNYALTW-NGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDD 366 Q + + W + ++ W Q ++R P G + + Q+ L D Sbjct: 264 SQTLSGKYTTDDWVFNLISA-WQQQHYSRT--FPSGSLIVNMPQRWNQDVQELRAATLGD 320 Query: 367 VMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPY 426 V+ L + ++++ + + + + Y Sbjct: 321 ART-----------VDMVFGLYRQNTREKLN-------------SAYDMPTMPYLSSTGY 356 Query: 427 SKAEIFSLFAENNMELTDSTIVTPGLRFDHHSI------------VGNNWSP-------A 467 + AE + +++ LTD + G+RF H G+ Sbjct: 357 TTAETLAAYSDLTWHLTDRFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQ 416 Query: 468 LNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAE 527 L+ L DD+ + +A+ YK PS Y P L +K AE Sbjct: 417 LSAGYMLTDDWRVYTRVAQGYK-PSGYNIVPTAGLDAKP-----------------FVAE 458 Query: 528 TSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEG 587 SIN E+G ++ F ++ + + + N KA G Sbjct: 459 KSINYELGTRYETADVTLQAATFYTHTKD--------MQLYSGPVRMQTLSNAGKADATG 510 Query: 588 LEGSLNVPVSETVMWTNN----ITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSM 643 +E + W N + G+R+ +P Y S+++ Sbjct: 511 VELEAKWRFAPGWSWDINGNVIRSEFTNDSELYHGNRVPFVPRYGAGSSVN--------- 561 Query: 644 QTTFTWYGKQQPKKYNYKGQPAV--GPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLF 701 T YG P+ P G Y+ + S W T+ ++++ VDNLF Sbjct: 562 GVIDTRYGALMPRLAVNLVGPHYFDGDNQLRQGTYATLDSSLGWQATERMNISVYVDNLF 621 Query: 702 DKRLWRAGNAQTTGDLAGANYIAGAGAYT 730 D+R G + +A N G T Sbjct: 622 DRRYRTYGYMNGSSAVAQVNMGRTVGINT 650 >5NEC-A nrPDB Length = 741 Score = 172 bits (436), Expect = 4e-43, Method: Composition-based stats. Identities = 134/774 (17%), Positives = 246/774 (31%), Gaps = 138/774 (17%) Query: 22 AQEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTG 81 ++ +T + D + L P T+ ++ K+ A + +RT+PG+ G Sbjct: 25 GEQQDETTYNVDRSASKKYTAPLLDTPRSVTVVPKQVIKDTAAVSLQDALRTVPGITF-G 83 Query: 82 NSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMI 141 G +R IRG ++ +DG RDT T + + Sbjct: 84 AGEGGNPTGDRPF-IRGFDAQSDT-YVDGV---------------RDTGAQTREI--FNL 124 Query: 142 ERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSL 201 E+IEV +GP +A G G+AGG +N+++K+ + + T+R L Sbjct: 125 EQIEVSKGPNSAFGGRGSAGGSLNLVSKQ------AKAGNFIDGGFTYGSDQTRRYTLDL 178 Query: 202 TGPLGD-EFSFRLYGNLDKTQA-----DAWDINQGHQSARAGTYATTLPAGREGVINKDI 255 D +FRL NL K A D D+++ A + T+ P Sbjct: 179 NQEFLDGNAAFRL--NLLKHDANVAGRDEVDVSR-WGVAPSLTFGLGSPTRV-----TVS 230 Query: 256 NGVVRWDFAPLQSLELEAGYSR------------QGNLYAGDTQNTNSDSYTRSKYGDET 303 + + D P + R +GN Y ++ S E Sbjct: 231 HYHLESDDTPDSGIPYAKSSDRSKHNPDKPVNVDRGNFYGLTGRDFQKSRIDTSTITVEH 290 Query: 304 NRLYRQNYALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQ------ 357 + + + + N W Q + ++ + + + + T Sbjct: 291 D--LTDSLTIRNTSRYGNSHQDYLWTQPDDSQGNINNGSVWRRQNNRVSTTTTAVNQTDL 348 Query: 358 -------DFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSS--NTQALTG 408 F + + E + ++V+ LG+ + S N +L Sbjct: 349 FGEFYLGGFKNSFSTGLEFSREDSKRDGYIVDTNTGLGSNKCNPSLIGAPSGYNCTSLEN 408 Query: 409 TNTGGAIDGVSTTDRSPYSK-AEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNN---- 463 N +G T +P + +++A + ++L + V G RFD N Sbjct: 409 PNPHDPWNGSITRKYAPLNTVGTTKAIYAFDTIDLNEQWQVNIGARFDSFETTAKNHGVR 468 Query: 464 -----------WSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYAS 512 W+ + + ++ A + P N + G Sbjct: 469 PATKLSDKSSFWNWQAGLVWKPVPNGSIYASYATSATPPGSMLDNGDTSNAVDGFAI--- 525 Query: 513 AGGCYLQGNDDLKAETSINKEIGLE--FKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAV 570 +++L+ E + N E+G + F + FR D N Sbjct: 526 --------SNNLEPEETTNYELGTKWAFFNERLELSAAIFRTDKDNTRILVANQT----- 572 Query: 571 GTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITY----------------MLKSEN 614 +DN ++ V+G+E S + ++E +Y + S Sbjct: 573 ------YDNAGQSRVDGVELSASGKLTEKWKVFAGYSYLDSELVDAGKAGRNGNVNASAA 626 Query: 615 KTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQ-PKKYNYKGQPAVGPETKEI 673 G+ + P+ NS W + T G K Y G P+ Sbjct: 627 SNNGNEMPNTPK---NSFSLWTTYDIFPKTTIGG--GAFYVDKVYGDVGNTVYVPD---- 677 Query: 674 SPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLW-RAGNAQTTGDLAGANYIAGA 726 Y A++ ++KNV V N+FDK+ + +A A AG + Sbjct: 678 --YWRYDAMASYKLSKNVDFQLNVQNVFDKKYFDKAYAAHYASQAAGRTILFST 729 >6E4V-A nrPDB Length = 693 Score = 169 bits (426), Expect = 6e-42, Method: Composition-based stats. Identities = 125/736 (16%), Positives = 232/736 (31%), Gaps = 118/736 (16%) Query: 16 IYGVAQAQEPTDTPVSHDDTIVVTAAEQNL-QAPGVSTITADEIRKNPVARDVSKIIRTM 74 + G A A + + S T T + P TI + + ++ + + +++ Sbjct: 10 VEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVMENT 69 Query: 75 PGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTS 134 G++ + + +R I ++DG P + G Sbjct: 70 LGISKSQADSDRALYYSRGFQI-------DNYMVDGIPTYFESRWNLGDALS-------- 114 Query: 135 WVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGAT 194 + ER+EV+RG G G +N++ K + + + Sbjct: 115 --DMALFERVEVVRGATGLMTGTGNPSAAINMVRKHATSR-----EFKGDVSAEYGSWNK 167 Query: 195 KRTNFSLTGPLGD--EFSFRLYGNLDKTQA--DAWDINQGHQSARAGTYATTLPAGREGV 250 +R L PL + + R+ G + D ++ + S L G Sbjct: 168 ERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGY 227 Query: 251 INKDIN-GVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQ 309 + I+ W P + + + + A D + + + + Sbjct: 228 EYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQ---FAD 284 Query: 310 NYALTWNGGWDNGVTTSNWVQYEHTRNSRIP------EGLAGGTEGKFNEKATQDFVDID 363 + T N S + + N G + +D Sbjct: 285 TWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVD 344 Query: 364 LDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQAL-TGTNTGGAIDG-VSTT 421 D+ L F L G +++Q + SS + +G T Sbjct: 345 ALDLFADGSYEL---FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQT 401 Query: 422 DRSPYSKAE-----IFSLFAENNMELTDSTIVTPGLRFDH-------HSIVGNNWSPALN 469 D SP S A+ + SL+A + L D + G R+ + +S+ N+ +P Sbjct: 402 DWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAG 461 Query: 470 ISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETS 529 + + D+++ ++ + ++ Y L T Sbjct: 462 LVFDINDNWSTYASYTSIFQPQNDRDSSGKY-----------------------LAPITG 498 Query: 530 INKEIGL--EFKRDGWLAGVTWFRNDYRNKIEA-GYVAVGQNAVGTDLYQWDNVPKAVVE 586 N E+GL ++ + FR + N ++ G G N + V V + Sbjct: 499 NNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPIPGSNGETA----YKAVDGTVSK 554 Query: 587 GLEGSLNVPVSETVMWTNNITYMLKSENK---------------TTGDRLSIIPEYTLNS 631 G+E LN +++ T T + +N+ T RL ++PE T+ Sbjct: 555 GVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLPVMPELTVGG 614 Query: 632 TLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNV 691 ++WQ R T T YG + E Y++V L + VTKN Sbjct: 615 GVNWQNR---VYTDTVTPYGTFR----------------AEQGSYALVDLFTRYQVTKNF 655 Query: 692 SLTGGVDNLFDKRLWR 707 SL G V+NLFDK Sbjct: 656 SLQGNVNNLFDKTYDT 671 >6FOK-A nrPDB Length = 723 Score = 164 bits (414), Expect = 1e-40, Method: Composition-based stats. Identities = 145/743 (19%), Positives = 242/743 (32%), Gaps = 120/743 (16%) Query: 36 IVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQID 95 VVT Q+ +P E R+ A D + ++T+PG + N G+N Sbjct: 69 SVVTGVAQS--SPLTIVTNPKEPRQPVPASDGADYLKTIPGFAVIRNG-----GSNGDPV 121 Query: 96 IRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARY 155 +RGM IL +G + R TS++ PE +++ V++GP + Sbjct: 122 LRGMFGSRLNILTNGGMMLGACPNR--------MDAPTSYISPETYDKLTVIKGPQTVLW 173 Query: 156 GNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSF-RLY 214 G GA+ G + E + G+ R + L G+ + R Sbjct: 174 GPGASAGTILF-----EREPERFGELGSRVNASLLAGSNGRFDKVLDAAAGNRLGYLRFT 228 Query: 215 GNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQS--LELE 272 GN Q+D ++ G+ K NG V + P + +EL Sbjct: 229 GN--HAQSDDYEDGAGNTVPS---------------RWKKWNGDVAVGWTPDEDTLIELT 271 Query: 273 AGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYE 332 AG YAG G + ++ R++ L + + + E Sbjct: 272 AGKGDGEARYAG--------------RGMDGSQFKRESLGLR----FVKSNVSDVLEKVE 313 Query: 333 HTRNSRIPEGLAGGTEGKF-NEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEW 391 + + + + + D L W Sbjct: 314 AQVYYNYADHIMDNFRLRTPDPSSMMPMPMASQVDRRTLGG-------------RLAATW 360 Query: 392 NQQRMK-----DLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIF---SLFAENNMELT 443 K D N G+ D + D+ P+SK +F F E Sbjct: 361 RWDDFKLVTGVDAMRNEHRARGSKYDMMTDYYTDADQFPWSKDAVFHNYGAFGELTWFAA 420 Query: 444 DSTIVTPGLRFDHHS--------IVGNNWSPALNISQGLGDDFTLKMGIAR-----AYKA 490 + + GLR D S G+ N + TL G R A Sbjct: 421 ERDRLIGGLRLDRASVKDYRQTLKSGHMGHAMANPTANDTRADTLPSGFVRYEHDLADSP 480 Query: 491 PSLY------QTNPN-YILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGW 543 +LY + P+ + L+S +G S D +K E + + GL++ D Sbjct: 481 TTLYAGLGHAERFPDYWELFSPKRGPNGSVNAF-----DKIKPEKTTQLDFGLQYNGDKL 535 Query: 544 LAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWT 603 A + + ++ I Y + Q NV A + G E + ++ Sbjct: 536 QAWASGYVGVVQDFILFSYREGMMGSST----QATNVD-ARIMGGELGASYQLTGNWKTD 590 Query: 604 NNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQ 663 ++ Y +N + L IP L++ E+ W + Sbjct: 591 ASLAYAW-GKNSSDDRALPQIPPLEARFGLTY---EEGDWSAGSLWRVVAPQNRIARDQG 646 Query: 664 PAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYI 723 VG + + + + + L+ + VT+NV L+ GVDNLFDK N AG + Sbjct: 647 NVVGKDFDKSAGFGVFSLNGAYRVTRNVKLSAGVDNLFDKDYTEHLN---KAGDAGFGFS 703 Query: 724 AGAGAYTYNEPGRTWYMSVNTHF 746 A T EPGRT++ V+ F Sbjct: 704 ANE---TVPEPGRTFWTKVDFSF 723 >1KMO-A nrPDB Length = 774 Score = 163 bits (413), Expect = 2e-40, Method: Composition-based stats. Identities = 120/735 (16%), Positives = 251/735 (34%), Gaps = 113/735 (15%) Query: 28 TPVSHDDTIVVTA-------AEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLT 80 P +D + V + G + E A + +++ +PGV+ Sbjct: 107 APAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRIPGVSAP 166 Query: 81 GNSTSGQRGNNRQIDIRGMGPE---NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVP 137 N+ +G IRG+ P + +L+DG PV + S P Sbjct: 167 ENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPY----------GQPQLSLAP 216 Query: 138 PE--MIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGE--WHGSWDAYFNAPEHKEEGA 193 ++ I+V+RG A RYG + GGVVN +T+ + + + P + Sbjct: 217 VSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLS-PTSSQNNP 275 Query: 194 TKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINK 253 + N + G + F L T+ W RE + Sbjct: 276 KETHNLMVGGTADNGFGTALL--YSGTRGSDW---------------------REHSATR 312 Query: 254 DINGVVRWDFAPLQSLELEA---GYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQN 310 + +++ +AP + + Y + ++ G ++ +S + R+ Sbjct: 313 IDDLMLKSKYAPDEVHTFNSLLQYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKL 372 Query: 311 YALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLH 370 +L + D+ + Y T S E ++ T + + + Sbjct: 373 ASLGYQFQPDSQHKFNIQGFYTQTLRSGYLEQ---------GKRITLSPRNYWVRGIEPR 423 Query: 371 SEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAE 430 + + + +G + + + + + T T++G G S DR S E Sbjct: 424 YS-QIFMIGPSAHEVGVGYRY----LNESTHEMRYYTATSSGQLPSGSSPYDRDTRSGTE 478 Query: 431 IFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKA 490 + + ++ +++ + +TPG+RF+H NN A+ + +Y A Sbjct: 479 AHAWYLDDKIDI-GNWTITPGMRFEHIESYQNN---AITGTHEEV-----------SYNA 523 Query: 491 P-----SLYQTNPNYILYSKGQGCYAS---AGGCYLQGNDDLKAETSINKEIGLEFKRDG 542 P LY ++ LY+ +G + + + + +++ E + E+G + Sbjct: 524 PLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVEPEKARTWELGTRYDDGA 583 Query: 543 WLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVS----- 597 A + F ++ N+ ++ A G K GLE + Sbjct: 584 LTAEMGLFLINFNNQYDSNQTNDTVTARG----------KTRHTGLETQARYDLGTLTPT 633 Query: 598 -ETVMWTNNITYM---LKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQ 653 + V + Y+ ++ + T G+ + P++ + ++ + + + Q Sbjct: 634 LDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKP-GNWTFNLNSDFQSSQ 692 Query: 654 QPKKYNYKGQPAVGPETKEISPYSIVGLSATWDV---TKNVSLTGGVDNLFDKRLW-RAG 709 N + A G T I + + G +D +++L GV N+FD+ + R+ Sbjct: 693 FADNANTVKESADG-STGRIPGFMLWGARVAYDFGPQMADLNLAFGVKNIFDQDYFIRSY 751 Query: 710 NAQTTGDLAGANYIA 724 + G AG Sbjct: 752 DDNNKGIYAGQPRTL 766 >5FP1-A nrPDB Length = 718 Score = 155 bits (390), Expect = 9e-38, Method: Composition-based stats. Identities = 138/787 (17%), Positives = 246/787 (31%), Gaps = 160/787 (20%) Query: 25 PTDTPVSHDDTIVVTAAEQN------LQAPGVSTITADEIRKNPVARDVSKIIRTMPGVN 78 T + ++++ V + + L P ++ + ++ ++ ++ +RT+PG+ Sbjct: 12 TIHTKATQEESLKVDQSANSKFVAPLLDTPKSVSVISKQLIEDTKVTTLADALRTVPGIT 71 Query: 79 LTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPP 138 L G G +R IRG E+++ IDG RNS Q Sbjct: 72 L-GAGEGGNPNGDRPF-IRGYSSESSM-YIDGI----RNSTSQNREM------------- 111 Query: 139 EMIERIEVLRGPAAARYGNGAAGGVVNIITK--KGSGEWHGSWDAYFNA----------- 185 +E++EV +G A+A G G+ GG +N+I+K K GS A + Sbjct: 112 FAVEQVEVTKGSASAMGGAGSVGGSINMISKVAKKGDFLEGSVAAGTDNYQRITLDGNKD 171 Query: 186 ------------------------PEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQ 221 E+K G F L P S+ DK Sbjct: 172 FGNGIAARVAVLGHQNEKAGQSNGAEYKRVGIAPSITFGLDTPTRATLSYYYLQTDDKPD 231 Query: 222 A--DAWDINQGHQSARAGTYATTLPAGREGVINKDING--------VVRWDFAPLQSLEL 271 + WD + G G A G ++D + D ++ Sbjct: 232 SGIPYWDSSLG---KAQGKPAEVKQGTYYGWKDRDFQKQENHIGTIKLEHDLTDNITITN 288 Query: 272 EAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWN----GGWDNGVTTSN 327 A Y++ N Y + + + + N + T G +D G Sbjct: 289 TAMYAKSKNDYVWTNPDDSKGNVGKGLVWHRLNSAITDSETFTDQLALTGKFDTGFLKHR 348 Query: 328 WVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTL 387 + + +G + K N +T + D L Sbjct: 349 FNVGAEYSKQKTDKGGYNIIDAKGNVSSTGFYSDCS----------------------DL 386 Query: 388 GTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTI 447 T W +L G +D + + E S++ +N+E+T + Sbjct: 387 STNW-----------CTSLNGPTQKPFVDRLQARP-DFDATVESTSVYLLDNIEITPKWL 434 Query: 448 VTPGLRFDHHS---IVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYS 504 + GLR+D S A ++ D T + GI +K +Y + Sbjct: 435 LDLGLRWDKFEAEQNFLATSSAAAYTAKNNSDFVTYQAGI--TFKPTENGSIYTSYATSA 492 Query: 505 KGQGC---YASAGGCYLQGNDDLKAETSINKEIG--LEFKRDGWLAGVTWFRNDYRNKIE 559 G + N + E + EIG +F + FR + +N Sbjct: 493 SPVGLNAGWGDNSETINANNQMIDPEEAQTFEIGTKWDFLDNHLNLTAAIFRTEKQN--- 549 Query: 560 AGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENK---- 615 V D + NV ++ V+G E LN +++ + TY+ K Sbjct: 550 --------TRVQIDPTTYANVGESKVDGFELGLNGEITDKWNISAGYTYLDSELTKNGKS 601 Query: 616 -----------TTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQP 664 G+++ +P+ +++ L++ + K Sbjct: 602 CRSGKCTDQSIYNGNQMPNVPKQAATLWTTYKVLPQLTVGAGAVYSDKVY---------- 651 Query: 665 AVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIA 724 TK + Y A ++V KNV L ++NL DKR + A A Sbjct: 652 GDVANTKWVPSYVRYDAMARYNVNKNVDLQLNINNLSDKRYFTKAYASHYATEAEGRSAV 711 Query: 725 GAGAYTY 731 A + Y Sbjct: 712 LAVNFKY 718 >2W78-A nrPDB Length = 772 Score = 148 bits (374), Expect = 7e-36, Method: Composition-based stats. Identities = 123/713 (17%), Positives = 225/713 (31%), Gaps = 97/713 (13%) Query: 37 VVTAAEQNL---QAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQ 93 + TA L + P T+ + + ++ ++R PG+ ++ T + Sbjct: 109 IATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDT-----DRNN 163 Query: 94 IDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAA 153 RG N DG P ++RN + + +R+EVL+G Sbjct: 164 YYARGFSINNFQY--DGIPSTARNV---------GYSAGNTLSDMAIYDRVEVLKGATGL 212 Query: 154 RYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRL 213 G G+ G +N+I KK + E+ G + R+ ++GPL + Sbjct: 213 LTGAGSLGATINLIRKKPTHEFKGHVELGA------GSWDNYRSELDVSGPLTES----- 261 Query: 214 YGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEA 273 GN+ A+ + G++ +D P L + A Sbjct: 262 -GNVRGRAVAAYQDKHSFMDHYERKTSV-------------YYGILEFDLNPDTMLTVGA 307 Query: 274 --------GYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTT 325 G G+ D+Q +D G + + + + N + Sbjct: 308 DYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGW 367 Query: 326 SNWVQYEHTRN-SRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNL--PIDFL-V 381 VQ +H N P G G + A + ++ L P FL Sbjct: 368 VGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGR 427 Query: 382 NQTLTLGTE-----WNQQR---MKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFS 433 L +GT W + +++ + T + T + K Sbjct: 428 EHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLG 487 Query: 434 LFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSL 493 + +TD + G R + + G N P + S ++ Sbjct: 488 SYMTARFNVTDDLNLFLGGRVVDYRVTGLN--PTIRESGRFIPYVG------------AV 533 Query: 494 YQTNPNYILYSKGQGCYASAGGCYL-QGNDDLKAETSINKEIGL--EFKRDGWLAGVTWF 550 Y N Y +Y+ + Y N L+ + N EIG+ E+ + +F Sbjct: 534 YDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYF 593 Query: 551 RNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYML 610 N+ E + + Y + + KA +G E ++ ++ T+ + Sbjct: 594 EIHEENRAEEDALYNSKPTNPAITYAYKGI-KAKTKGYEAEISGELAPGWQVQAGYTHKI 652 Query: 611 KSENK-------TTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQ 663 ++ D+LS+ Y L L++ W GK YN Sbjct: 653 IRDDSGKKVSTWEPQDQLSLYTSYKFKGALD-----KLTVGGGARWQGKSWQMVYN---N 704 Query: 664 PAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGD 716 P E Y +V L A + +T +S + V+N+FDK + T+ Sbjct: 705 PRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSAS 757 >1XKH-A nrPDB Length = 687 Score = 146 bits (368), Expect = 3e-35, Method: Composition-based stats. Identities = 123/713 (17%), Positives = 225/713 (31%), Gaps = 97/713 (13%) Query: 37 VVTAAEQNL---QAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQ 93 + TA L + P T+ + + ++ ++R PG+ ++ T + Sbjct: 24 IATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDT-----DRNN 78 Query: 94 IDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAA 153 RG N DG P ++RN + + +R+EVL+G Sbjct: 79 YYARGFSINNFQY--DGIPSTARNV---------GYSAGNTLSDMAIYDRVEVLKGATGL 127 Query: 154 RYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRL 213 G G+ G +N+I KK + E+ G + R+ ++GPL + Sbjct: 128 LTGAGSLGATINLIRKKPTHEFKGHVELGA------GSWDNYRSELDVSGPLTES----- 176 Query: 214 YGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEA 273 GN+ A+ + G++ +D P L + A Sbjct: 177 -GNVRGRAVAAYQDKHSFMDHYERKTSV-------------YYGILEFDLNPDTMLTVGA 222 Query: 274 --------GYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTT 325 G G+ D+Q +D G + + + + N + Sbjct: 223 DYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGW 282 Query: 326 SNWVQYEHTRN-SRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNL--PIDFL-V 381 VQ +H N P G G + A + ++ L P FL Sbjct: 283 VGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGR 342 Query: 382 NQTLTLGTE-----WNQQR---MKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFS 433 L +GT W + +++ + T + T + K Sbjct: 343 EHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLG 402 Query: 434 LFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSL 493 + +TD + G R + + G N P + S ++ Sbjct: 403 SYMTARFNVTDDLNLFLGGRVVDYRVTGLN--PTIRESGRFIPYVG------------AV 448 Query: 494 YQTNPNYILYSKGQGCYASAGGCYL-QGNDDLKAETSINKEIGL--EFKRDGWLAGVTWF 550 Y N Y +Y+ + Y N L+ + N EIG+ E+ + +F Sbjct: 449 YDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYF 508 Query: 551 RNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYML 610 N+ E + + Y + + KA +G E ++ ++ T+ + Sbjct: 509 EIHEENRAEEDALYNSKPTNPAITYAYKGI-KAKTKGYEAEISGELAPGWQVQAGYTHKI 567 Query: 611 KSENK-------TTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQ 663 ++ D+LS+ Y L L++ W GK YN Sbjct: 568 IRDDSGKKVSTWEPQDQLSLYTSYKFKGALD-----KLTVGGGARWQGKSWQMVYN---N 619 Query: 664 PAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGD 716 P E Y +V L A + +T +S + V+N+FDK + T+ Sbjct: 620 PRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSAS 672 >1FCP-A nrPDB Length = 705 Score = 139 bits (350), Expect = 3e-33, Method: Composition-based stats. Identities = 123/731 (16%), Positives = 234/731 (32%), Gaps = 123/731 (16%) Query: 26 TDTPVSH--DDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNS 83 TDTP+ VVTA E L P + V + + PGV++ Sbjct: 21 TDTPIQKVPQSISVVTAEEMALHQP----------------KSVKEALSYTPGVSV---G 61 Query: 84 TSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIER 143 T G + IRG E S+N+ G + + + D + + P M+ER Sbjct: 62 TRGASNTYDHLIIRGFAAEG----------QSQNNYLNGLKLQGNFYND-AVIDPYMLER 110 Query: 144 IEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTG 203 E++RGP + YG + GG++N+++K+ + E + G + G Sbjct: 111 AEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLDDDG 170 Query: 204 PLGDEFSFRLYG---NLDKTQADAWDINQGHQSARA-GTYATTLPAGREGVINKDINGVV 259 +S+RL G + + Q + + A T N+ G Sbjct: 171 ----VYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYY 226 Query: 260 RWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGW 319 W L G + G NT S + G + + + + N + Sbjct: 227 GWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRN--EKMVGYSFDHEFNDTFTVRQNLRF 284 Query: 320 DNGVTTSNWVQ-YEHTRN--SRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLP 376 T+ N V Y + + + A + +V D + L Sbjct: 285 AENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDTQLQ 344 Query: 377 IDFL---VNQTLTLGTEWNQQR-----------------MKDLSSNTQALTGTNTGGAID 416 F ++ TL G ++ + R + + S + NT + Sbjct: 345 SKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPSHHHHHHGSVNTDFDFN 404 Query: 417 GVSTTDRSPY---SKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQG 473 + PY +K + ++ ++ + D +VT G R+D W+ ++++ Sbjct: 405 AKDPANSGPYRILNKQKQTGVYVQDQAQ-WDKVLVTLGGRYD--------WADQESLNRV 455 Query: 474 LGDD-------FTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKA 526 G FT + G+ Y + Y + + GN Sbjct: 456 AGTTDKRDDKQFTWRGGVN--------YLFDNGVTPYFSYSESFEPSSQVGKDGNI-FAP 506 Query: 527 ETSINKEIGLEF---KRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKA 583 E+G+++ R + G + N + + G + Sbjct: 507 SKGKQYEVGVKYVPEDRPIVVTGAVYNLTKTNNLMADPEGSFFSVEGG----------EI 556 Query: 584 VVEGLEGSLNVPVSETVMWTNNITYMLKSENKTT---GDRLSIIPEYTLNSTLSWQARED 640 G+E +S +V + TY T G+ + +P++ + + + Sbjct: 557 RARGVEIEAKAALSASVNVVGSYTYTDAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDG 616 Query: 641 LSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTK------NVSLT 694 T G+ Y + ++ Y++V +D+ + NV+L Sbjct: 617 PLSGLTLGTGGRYTGSSYG------DPANSFKVGSYTVVDALVRYDLARVGMAGSNVALH 670 Query: 695 GGVDNLFDKRL 705 V+NLFD+ Sbjct: 671 --VNNLFDREY 679 >3QLB-A nrPDB Length = 748 Score = 132 bits (332), Expect = 5e-31, Method: Composition-based stats. Identities = 126/696 (18%), Positives = 230/696 (33%), Gaps = 110/696 (15%) Query: 48 PGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLIL 107 P ++ + + V++ +R GV + S QR + + IRG T +L Sbjct: 102 PQSISVITRDQMDAQQVQSVNEALRYTAGVQANTTAAS-QRFDT--LSIRGFD-VTTGML 157 Query: 108 IDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEM----IERIEVLRGPAAARYGNGAAGGV 163 DG +G+T+ P++ +ERI+VL+GPA+ +G + GGV Sbjct: 158 RDGL------------------KGNTAQAWPKVEAYGLERIDVLKGPASVLFGQNSPGGV 199 Query: 164 VNIITKKGSGEWHGSWDAYFNAPEHKEE---GATKRT--NFSLTGPLGDE--FSFRLYGN 216 VN I+K+ + P H+ + G+ R F +GPL DE F +RL G Sbjct: 200 VNQISKRP-----------LDKPFHEVQIQGGSFDRAQGQFDFSGPLDDEGQFLYRLVG- 247 Query: 217 LDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS 276 + + + T P N D + + D+ Sbjct: 248 -LERDSGTQFDHIKDDKQYFAPSFTWKP-------NDDTSLTLLADYTQDTFGAPRVFLP 299 Query: 277 RQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHTR- 335 QG L + + D Y Y L + +S +Y H Sbjct: 300 AQGTLLGNPNGKVRHNVFLDEPGLDNDRTQYSLGYLLEHRLNDVWSLNSS--ARYGHVNL 357 Query: 336 NSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLT-LGTEWNQQ 394 + G++ + + +A F + D L + + Q ++ LG ++ + Sbjct: 358 LTNTASGMSLAPDLRTLNRAAYRFRIVG-DTYSLDNNAQARWNLGSTQMVSLLGIDYRRT 416 Query: 395 RMK--------DLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDST 446 R + + G + ST + +A+ ++A+ + Sbjct: 417 REDYYLRGGSASPIDIYNPVHHHHHHGGVFDPSTPFTNTVQRADQVGVYAQQQFTFDEHW 476 Query: 447 IVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKG 506 ++T G R D S +N +N S DD Y A + P YI YS Sbjct: 477 VLTVGGRQDRSSARTDN---RMNDSGSKQDDEKFTYRTGLVYLADN--GLAP-YISYSTS 530 Query: 507 QGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG 566 + G G K ++ E+G++++ G + +T D + Sbjct: 531 ---FDPVLGTNFYGTP-YKPTSAKQSEVGVKYQPPGIDSYITLSLFDLTQENVLTTDP-- 584 Query: 567 QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRL----- 621 A + Q + V G+E ++ + +TY +E + + L Sbjct: 585 --AQRLNKIQ---TGEINVRGIELEGKASLARGLDLLAALTY-NDAEVSKSNNPLEKGKR 638 Query: 622 -SIIPEYTLNSTLSWQARE----DLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPY 676 + PE + + E L + G A T+ + Y Sbjct: 639 PTDTPEKMASLWADYTLPEGPLSGLGFGAGVRYIG----------STEADAANTQRVPSY 688 Query: 677 SIVGLSATWDV------TKNVSLTGGVDNLFDKRLW 706 +++ + +D K + L NL DK + Sbjct: 689 TLLDAAVHYDFDKLIPAAKGLRLAVNATNLTDKHYY 724 >5FQ8-B nrPDB Length = 984 Score = 119 bits (298), Expect = 4e-27, Method: Composition-based stats. Identities = 90/489 (18%), Positives = 170/489 (34%), Gaps = 66/489 (13%) Query: 26 TDTPVSHDDTIVVTAA--EQNLQAPG--VSTITADEIRKNPVARDVSKIIRTMPGVNLTG 81 + D +VVTA +++ +A G +++ ++I ++ + +S + + GV ++ Sbjct: 16 LRSDAQQIDEVVVTAMGIKRSEKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQIS- 74 Query: 82 NSTSGQRGNNRQIDIRGM----GPENTLILIDGKPVSSRNSVR-QGWRGERDTRGDTSWV 136 STS G + + IRG+ G L ++DG P+++ G D + + Sbjct: 75 -STSSDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAI 133 Query: 137 PPEMIERIEVLRGPAA-ARYGNGAAGGVVNIITKKG------SGEWHG--SWDAYFNAPE 187 P+ + + +L+G AA A YG+ AA GVV I TK G E++G W PE Sbjct: 134 NPDDVANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWSTVLRLPE 193 Query: 188 HKEE------GATKRTNFSLTGPLGDEFSFRLYGNLDKTQ-------------ADAWDIN 228 + E G GP D S +L+GN+ D +D Sbjct: 194 FQNEFGMGWNGNHTELENGSWGPRFDG-SMQLWGNVYNNSQKLKPYVAMPDNIKDFFDAG 252 Query: 229 QGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQN 288 + ++ + AT +G++ D A S + + Sbjct: 253 FRYSNSLSFNGATDKSDYYVSFSQISDDGMIPTDADSYDKYTFSARGSHKAGALTFSSSL 312 Query: 289 TNS----DSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLA 344 + + T + N LY+ ++ + E + G Sbjct: 313 NYAYQKNNFATTGQGLSMLNSLYQTPRDIS-------------IIGLEDQNDPFNTPGYY 359 Query: 345 GGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDF--LVNQTLTLGTEWNQQRMKDLSSN 402 G N + + + + + L +F T +G + + N Sbjct: 360 YTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEFLKYFKFTYRMGLDTTTGQSDKGKPN 419 Query: 403 TQALTGTNTGGAIDGVSTTDRSPYS-KAEIFSLFAENNMELTDSTIVTPGLRFDH---HS 458 AL T +G SP+S + +S E+ +V + + ++ Sbjct: 420 LYALYYEGT---PNGEGQGSSSPFSGETGQYSEQITRRREINQDIMVNFNMPVNDFNINA 476 Query: 459 IVGNNWSPA 467 +VG N + Sbjct: 477 LVGFNGNER 485 >1XKW-A nrPDB Length = 665 Score = 118 bits (295), Expect = 9e-27, Method: Composition-based stats. Identities = 107/713 (15%), Positives = 204/713 (28%), Gaps = 114/713 (15%) Query: 48 PGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLIL 107 P +++ E + + + ++ GV + +RG + Sbjct: 25 PQSASVIDHERLEQQNLFSLDEAMQQATGVTVQPFQL-----LTTAYYVRGF--KVDSFE 77 Query: 108 IDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNII 167 +DG P N+ S + ER+E+LRG +G G VN++ Sbjct: 78 LDGVPALLGNTAS-------------SPQDMAIYERVEILRGSNGLLHGTGNPAATVNLV 124 Query: 168 TKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDI 227 K+ E+ S R + GPL + R D + Sbjct: 125 RKRPQREFAASTTL------SAGRWDRYRAEVDVGGPLSASGNVRGRAVAAYEDRDYF-- 176 Query: 228 NQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYA---- 283 + A GT + + GV +D +P L + A Y ++ Sbjct: 177 ---YDVADQGT--------------RLLYGVTEFDLSPDTLLTVGAQYQHIDSITNMAGV 219 Query: 284 -----GDTQNTNSDSYTRSKYGDETNRLYRQNYALTWN--GGWDNGVTTSNWVQYEHTRN 336 G + D+Y + YR +L GGW G ++ + + + Sbjct: 220 PMAKDGSNLGLSRDTYLDVDWDRFKWDTYRAFGSLEQQLGGGWK-GKVSAEYQEADSRLR 278 Query: 337 SRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLP--------IDFLVNQTLTLG 388 G G + + + + + NL L+ Sbjct: 279 Y---AGSFGAIDPQTGDGGQLMGAAYKFKSIQRSLDANLNGPVRLFGLTHELLGGVTYAQ 335 Query: 389 TEWNQQR---MKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDS 445 E Q + ++ G + + L+A ++L + Sbjct: 336 GETRQDTARFLNLPNTPVNVYRWDPHGVPRPQIGQYTSPGTTTTTQKGLYALGRIKLAEP 395 Query: 446 TIVTPGLR--FDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILY 503 + G R + + P G FT G+ ++ ++ Y Sbjct: 396 LTLVVGGRESWWDQDTPATRFKP--------GRQFTPYGGL--------IWDFARDWSWY 439 Query: 504 SKGQGCYASAGGCYLQGNDDLKAETSINKEIGL--EFKRDGWLAGVTWFRNDYRNKIEAG 561 Y ++ L E G+ E + FR D N Sbjct: 440 VSYAEVYQPQADRQTWNSEPLSPVEGKTYETGIKGELADGRLNLSLAAFRIDLENN---P 496 Query: 562 YVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITY----MLKSENKTT 617 + + + + K +G E ++ + TY LK + Sbjct: 497 QEDPDHPGPPNNPF-YISGGKVRSQGFELEGTGYLTPYWSLSAGYTYTSTEYLKDSQNDS 555 Query: 618 GDRLSI-IPEYTL----NSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKE 672 G R S P + L N L WQ R S+ G Q Y+ + + Sbjct: 556 GTRYSTFTPRHLLRLWSNYDLPWQDR-RWSVGG-----GLQAQSDYSVDYRGV----SMR 605 Query: 673 ISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAG 725 Y++V + + + ++ + V+NLFD+ +++ + + G Sbjct: 606 QGGYALVNMRLGYKIDEHWTAAVNVNNLFDRTYYQSLSNPNWNNRYGEPRSFN 658 >3EFM-A nrPDB Length = 707 Score = 109 bits (272), Expect = 4e-24, Method: Composition-based stats. Identities = 107/727 (14%), Positives = 213/727 (29%), Gaps = 141/727 (19%) Query: 46 QAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTL 105 + P ++ + ++ D I+ T PG+++T + + N RG +N Sbjct: 49 ETPQSVSVVTRQQIEDQGLTDTGAILATAPGISVTRSDS-----NRYSFSARGFTIDN-- 101 Query: 106 ILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVN 165 DG + G ++ + + + +E++RG G+G VN Sbjct: 102 FQFDGLVSPILSQWNYG----------STDMDAAIYDHVEIVRGATGLMTGSGNPSAAVN 151 Query: 166 IITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAW 225 + K+ E+ +++A R + ++ P+ ++ R +Q D++ Sbjct: 152 FVRKRPLREFAATFNASV------GSWDYVRGDADISVPITEDGRIRSRLVAAYSQGDSY 205 Query: 226 DINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGD 285 + R Y GV++ D+ + G+ L+ D Sbjct: 206 --VHFLDTRRRTFY---------GVVSADLTPDTVLTTSVEYQHNHSNGFGSGFPLFYSD 254 Query: 286 TQNTNSDSYTRSKYGDETNRLYRQNY--ALTWNGGWDNGVTTSNWVQYEHT-----RNSR 338 T+ + + Y LT D Y HT Sbjct: 255 GSRTDFNRSVANNAPWARQDTEATTYFVDLTHRFTNDW----KLRAAYSHTDGRYLMKHV 310 Query: 339 IPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPID-FLVNQTLTLG-------TE 390 G G D +LD +H ++ P + F + + LG ++ Sbjct: 311 YRGGYPDRHTGIIAAPPAFSNYDGNLDRDDIHFSLSAPFEAFGLRHEVALGWMSIDNHSD 370 Query: 391 WNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPY----------SKAEIFSLFAENNM 440 + M + + G+ + P + + + Sbjct: 371 IQRYAMVGPAPAIGSFFDWRRAGSHHHHHHHIQEPSWADTLSPADDVRTKQTGAYLVGRF 430 Query: 441 ELTDSTIVTPGLRFDHHSI----VG--------NNWSPALNISQGLGDDFTLKMGIARAY 488 L + + G R+ G N ++P ++ + D +T + Sbjct: 431 ALAEPLHLIVGDRWSDWKTKQMYFGSRREYRIKNQFTPYAGLTYDINDTYTAYASYTEIF 490 Query: 489 KAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLE--FKRDGWLAG 546 + + T+ L S + E+GL+ + Sbjct: 491 QPQNARDTSGGI-----------------------LPPIKSKSYELGLKAAYLEGRLNTS 527 Query: 547 VTWF--RNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTN 604 F R D ++ G G + A VEG++ + + Sbjct: 528 AALFQTRQDNLAQVIPGSSIPGFPNMQAS----RAASGAKVEGIDLEASGQILPDWNIGA 583 Query: 605 NITYMLKSENK---------------TTGDRLS-IIPEYTLNSTLSWQAREDLSMQTTFT 648 + T+ + T RL + T+ + WQ+R Q + Sbjct: 584 SYTHFTTKDASGNPINTNHPRSLFKLYTTYRLPGALHRLTVGGGVDWQSRM---YQAAAS 640 Query: 649 WYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRA 708 G + E Y++V L A +D K +S T V+NLFDK+ + Sbjct: 641 PRGNVE----------------VEQDSYALVSLMARFDFNKKLSATLNVNNLFDKKYYDQ 684 Query: 709 GNAQTTG 715 + G Sbjct: 685 IGFYSQG 691 >4AIP-A nrPDB Length = 742 Score = 99.3 bits (245), Expect = 5e-21, Method: Composition-based stats. Identities = 111/717 (15%), Positives = 220/717 (30%), Gaps = 97/717 (13%) Query: 34 DTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQ 93 DT+ V Q + + +T + ++ A D+ ++++ P ++ G + + Q Sbjct: 54 DTVTVKGDRQGSKI-RTNIVTLQQKDEST-ATDMRELLKEEPSIDFGGGNGTSQ-----F 106 Query: 94 IDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAA 153 + +RGMG + I +D S+ QG V P +++ + V +G +A Sbjct: 107 LTLRGMGQNSVDIKVDNAYSDSQILYHQGRFI----------VDPALVKVVSVQKGAGSA 156 Query: 154 RYGNGAAGGVVNIITKKGSGEWHG---SWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFS 210 G GA G + T G +W N+ G + + G E + Sbjct: 157 SAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNNGVSYGASVF-----GKEGN 211 Query: 211 FRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINK--DINGVVRWDFAPLQS 268 F + ++ ++ +G ++ G + + K G Sbjct: 212 FDGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGTTFGDDDHRIVLSHM 271 Query: 269 LELEAGYSRQGNLYA-GDTQNTNSDSYTRSKYGDETNRLYRQNYALTWN--GGWDNGVTT 325 + G + GD + + R N A T G + Sbjct: 272 KDQHRGIRTVREEFTVGDKSSR--INIDRQAPAYRETTQSNTNLAYTGKNLGFVEKLDAN 329 Query: 326 SNWVQYEHTRNSRIPEGLAGGTEG-----KFNEKATQDFVDIDLDDVMLHSEVNLPIDFL 380 + ++ E G AG +G A +F + +L +N + Sbjct: 330 AYVLEKERYSADDSGTGYAGNVKGPNHTRITTRGANFNFDSRLAEQTLLKYGINYRHQEI 389 Query: 381 VNQ-------TLTLGTEWNQQRMKDLSSNT---QALTGTNTGGAIDGVSTTDRSPYSKAE 430 Q ++ E N Q++ +A T + + TD Y +A Sbjct: 390 KPQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKDRADEDTVHAYKLSNPTKTDTGVYIEA- 448 Query: 431 IFSLFAENNMELTDSTIVTPGLRFDH--------HSIVGNNWSPALNISQGLGDDFTLKM 482 + +T GLR+D ++ +N +P+ + + ++ Sbjct: 449 ---------IHDIGDFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSA 499 Query: 483 GIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDG 542 A ++P LY + D KAE + N EIG + Sbjct: 500 SHNYASRSPRLY------------DALQTHGKRGIISIADGTKAERARNTEIGFNYNDGT 547 Query: 543 WLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSL---NVPVSET 599 + A ++F ++ + AV + N G E ++ Sbjct: 548 FAANGSYFWQTIKDALANPQNRHDSVAVREAV----NAGYIKNHGYELGASYRTGGLTAK 603 Query: 600 VMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQ---TTFTWYGKQQPK 656 V +++ + LS PE+ +W A Q W G+ K Sbjct: 604 VGVSHSKPRFYDTHK---DKLLSANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQK 660 Query: 657 KYNY-----KGQPAVGPETKEISPYSIVGLSATWDV--TKNVSLTGGVDNLFDKRLW 706 + E + + + A W +++ V+N+F+K + Sbjct: 661 ATGSILAAGQKDRKGNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNKFYY 717 >4B7O-A nrPDB Length = 745 Score = 94.7 bits (233), Expect = 2e-19, Method: Composition-based stats. Identities = 108/712 (15%), Positives = 217/712 (30%), Gaps = 84/712 (11%) Query: 34 DTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQ 93 DT+ V Q + + +T + ++ A D+ ++++ P ++ G + + Q Sbjct: 54 DTVTVKGDRQGSKI-RTNIVTLQQKDEST-ATDMRELLKEEPSIDFGGGNGTSQ-----F 106 Query: 94 IDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAA 153 + +RGMG + I +D S+ QG V P +++ + V +G +A Sbjct: 107 LTLRGMGQNSVDIKVDNAYSDSQILYHQGRFI----------VDPALVKVVSVQKGAGSA 156 Query: 154 RYGNGAAGGVVNIITKKGSGEWHG---SWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFS 210 G GA G + T G +W N+ EG + + G E + Sbjct: 157 SAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNEGVSYGASVF-----GKEGN 211 Query: 211 FRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINK--DINGVVRWDFAPLQS 268 F + ++ ++ +G ++ G + + K G Sbjct: 212 FDGLFSYNRNDEKEYEAGKGFRNFNGGKTVPYSALDKRSYLAKIGTTFGDGDHRIVLSHM 271 Query: 269 LELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNG-GWDNGVTTSN 327 + G + ++ ++ ++ ET + N L + G Sbjct: 272 EDQHRGIRTVREEFTVGDASSRTNITRQAPPYRETTQ---SNTNLAYTGKDLGFVEKLDA 328 Query: 328 WVQYEHTRNSRIPE---GLAGGTEG-----KFNEKATQDFVDIDLDDVMLHSEVNLPIDF 379 + + G AG G +F + +L +N Sbjct: 329 NAYVLEKKRYSADDKDNGYAGNVVGPNHTRITTRGMNFNFDSRLAEQTLLKYGINYRHQE 388 Query: 380 LVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYS----KAEIFSLF 435 + Q G + KD + + T+ A D Y + Sbjct: 389 IKPQAFLNGEFEISGKKKDPKDPKKEIDKTDEEKAKDKKDMDLVHSYKLSNPTKTDTGAY 448 Query: 436 AENNMELTDSTIVTPGLRFDH--------HSIVGNNWSPALNISQGLGDDFTLKMGIARA 487 E + D +T GLR+D ++ +N +P+ + + ++ A Sbjct: 449 IE-AIHELDGFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWSFSSSHNYA 507 Query: 488 YKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGV 547 ++P LY + D KAE + N EIG + + A Sbjct: 508 SRSPRLY------------DALQTHGKRGIISIADGTKAERARNTEIGFNYNDGTFAANG 555 Query: 548 TWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSL---NVPVSETVMWTN 604 ++F ++ + AV + N G E ++ V ++ Sbjct: 556 SYFWQTIKDALANPQNRHVSAAVREAV----NAGYIKNHGYELGASYRTGGLTAKVGVSH 611 Query: 605 NITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQ---TTFTWYGKQQPKK---- 657 + + K LS PE+ +W A Q W G+ K Sbjct: 612 SKPRFYDTHPKKL---LSANPEFGAQVGRAWTASLAYRFQNPNLEIGWRGRYVQKAVGSI 668 Query: 658 -YNYKGQPAVGPETKEISPYSIVGLSATWDV--TKNVSLTGGVDNLFDKRLW 706 + E + + + A W +++ V+N+F+ + Sbjct: 669 LVAGQKDRNGKLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNTFYY 720 >3V8X-A nrPDB Length = 904 Score = 87.3 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 68/358 (18%), Positives = 112/358 (31%), Gaps = 49/358 (13%) Query: 423 RSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWS----------PALNISQ 472 + + +N+ L V GLR+D+ S ++ S I Sbjct: 562 TPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVL 621 Query: 473 GLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINK 532 D L + ++ PS + +Y G + A + E S NK Sbjct: 622 KPTDWLDLTYRTSTGFRLPSFAE------MYGWRAGVQSKAVK--------IDPEKSFNK 667 Query: 533 EIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQ--WDNVPKAVVEGLEG 590 E G+ FK D +WF N YR+ I GY A ++ + N A + G+ Sbjct: 668 EAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKDGKEEAKGDPAYLNAQSARITGINI 727 Query: 591 SLNVPVS-------ETVMWTNNITYMLKSENKTTGDRLSIIP---------EYTLNSTLS 634 + + E T + + K DR I Y + Sbjct: 728 LGKIDWNGVWDKLPEGWYSTFAYNRVRVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYD 787 Query: 635 WQAREDLSMQTTFTWYGKQQ------PKKYNYKGQPAVGPETKEISPYSIVGLSATWDVT 688 Q + T+ ++ + + P+ IV +S + V Sbjct: 788 -QPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTVK 846 Query: 689 KNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYMSVNTHF 746 K+ +L GV NL + R N + T A + Y PGR + S+ F Sbjct: 847 KHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEYKF 904 Score = 66.2 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 39/195 (20%), Positives = 70/195 (35%), Gaps = 18/195 (9%) Query: 20 AQAQEPTDTPVSHDDTIVVTAAEQNLQAPGVST-----ITADEIRKNPVARDVSKIIRTM 74 QAQE DTI V A +Q + T + + + ++ + R Sbjct: 19 GQAQE------KQLDTIQVKAKKQKTRRDNEVTGLGKLVKSSDTLSKEQVLNIRDLTRYD 72 Query: 75 PGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGER--DTRGD 132 PG+ + RG + IRGM + +DG + + G R + G Sbjct: 73 PGIAVVEQG----RGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGA 128 Query: 133 TSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEW-HGSWDAYFNAPEHKEE 191 + + E ++ +E+ +G + G+GA G V TK G + + + Sbjct: 129 INEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGK 188 Query: 192 GATKRTNFSLTGPLG 206 + +L G +G Sbjct: 189 NRGLTQSIALAGRIG 203 >6H7F-A nrPDB Length = 706 Score = 84.3 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 118/721 (16%), Positives = 208/721 (28%), Gaps = 109/721 (15%) Query: 41 AEQNLQAPGVSTITADEIRKNPVARDVSKIIRTM-PGVNLTGNSTSGQRGNNRQIDIRGM 99 +++ L P + D+ ++ A+D++++I P + G S G + IRG Sbjct: 54 SKKFLDTPFNTISYTDKYIEDKQAKDITEVIAATDPSIYTNGASG----GWSENYYIRGY 109 Query: 100 GPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYG--- 156 + ++G R PEM R+EVL+GP+A G Sbjct: 110 ASSTNDMSMNGL-FGITPFYRTS---------------PEMFGRVEVLKGPSALLNGMPP 153 Query: 157 NGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGN 216 G+ GG VN++TK + E A + + G+ F + N Sbjct: 154 AGSVGGTVNLVTKYAADEPFARLTT------TYMSDAQFGGHVDVGRRFGENKEFGVRIN 207 Query: 217 LDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQ-SLELEAGY 275 DA +Q +S + D G F +L+ G Sbjct: 208 GMYRDGDAAVNDQSKESRLFS-------------LGLDWQGENARVFVDAYDALDHVDGV 254 Query: 276 SRQGNLYA--GDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEH 333 +R N+ G + +D+ +G + ++ G +D + Y Sbjct: 255 TRGVNVSTAVGIPKPPKADTLLSPDWG----SVETKDKGAMIRGEYDFSDQLMAYAAYGQ 310 Query: 334 -TRNSRIPEGLAGGTEGK------------FNEKATQDFVDIDLDDVMLHSEVNL-PIDF 379 T + AG F+ + Sbjct: 311 STTEYKYNGASAGTITSSTGTLSSTLGQLAFDVDKKSADAGFKGKFETGSVKHQWVANAT 370 Query: 380 LVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSL----- 434 N T D N G + F L Sbjct: 371 YYNHTQDDYGYRIIPGFSDPVITNIYDPNPNWGPKPEFTPPFLFHSTLSTSSFGLADTLS 430 Query: 435 FAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLY 494 FA++ ++ +T GLR H V + ++N T G+A KA Sbjct: 431 FAQDKVQ------LTLGLR---HQTV--KATSSVNTLPENAKSAT-TPGVALLIKATDKI 478 Query: 495 QTNPNYILYSKGQGCYASAGGCYLQGNDD--LKAETSINKEIGLEFKRDGWLAGVTWFRN 552 NYI +G N + + +E+GL+ + ++ F Sbjct: 479 SVYANYI-----EGLTKGDQAPATASNPGEIFPPQKTKQQELGLKVDLGTFAHTLSAF-- 531 Query: 553 DYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKS 612 +I + + + +L + + + G+E S E V TY+ Sbjct: 532 ----EITKPSSYLDPSKLVNNLPTFVSDGEQRNRGIEWSFFGSPIEHVRLMGGFTYLDPE 587 Query: 613 ENKTT-----GDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVG 667 KT G +P+ W + Q T T G Y Sbjct: 588 LTKTKSGGNDGHTAVAVPKNQAKLGAEWDTQ---VAQGTLTLSGNINAVSKQYIN----A 640 Query: 668 PETKEISPYSIVGLSATW--DVTKN-VSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIA 724 T + +++ + A + V + V+ + NL +K W A Y+ Sbjct: 641 ENTLSVPGRTLLDVGARYSTKVEDHPVTFRANIYNLTNKAYWAQPQLTNLALGAPRTYML 700 Query: 725 G 725 Sbjct: 701 S 701 >3CSL-A nrPDB Length = 865 Score = 82.7 bits (202), Expect = 6e-16, Method: Composition-based stats. Identities = 126/787 (16%), Positives = 228/787 (28%), Gaps = 128/787 (16%) Query: 40 AAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGM 99 A + P ++ + E N AR + I+ G S+ Q+ ++IRG+ Sbjct: 112 ANDWVYDEPRSVSVISREQMDNRPARHAADILEQTTG----AYSSVSQQDPALSVNIRGI 167 Query: 100 -GPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNG 158 + IDG + + + R T ++ E++ + + +G G Sbjct: 168 QDYGRVNMNIDGMRQNFQ-------KSGHGQRNGTMYIDSELLSGVTIDKGTTGGMGSAG 220 Query: 159 AAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD 218 GG+ T S + + T + LG+E L + Sbjct: 221 TLGGIATFNTVSASDFLAPGKELGGKLHASTGDNGTHFIGSGILA-LGNETGDILLAASE 279 Query: 219 KTQADAWDINQGHQSARAGTYATTLPAG-REGVINKDIN----------GVVRWDFAPLQ 267 + D W N+G T E + N I V W+ Q Sbjct: 280 RHLGDYWPGNKGDIGNIRINNDTGNYDRYAESIKNNKIPDTHYRMHSRLAKVGWNLPANQ 339 Query: 268 SLEL-----EAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNG 322 L+L + G L T+ + R+ Y D R +Y+L D Sbjct: 340 RLQLSYLQTQTASPIAGTLTNLGTRPPYELGWKRTGYTDVMARNAAFDYSLAPE-DVDWL 398 Query: 323 VTTSNWVQYEHTRNSR-------IPEGLAGGTEGKF---NEKATQDFVDIDLDDVMLHSE 372 + + +S + G A T + + T F D + Sbjct: 399 DFQAKLYYVDTQDDSDTYSTSSLLDNGYATRTRLRTYGAQAQNTSRFSLAPGHDFRANYG 458 Query: 373 VNLPID--------FLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTGGAIDGV---STT 421 + D + G +L+ + G D T Sbjct: 459 LEFYYDKATSDSSRQGMEGVTPAGNRSVASLFANLTYDYDGWLTLEGGLRYDRYRLRGQT 518 Query: 422 DRSPYSKAEIFSLFAENN----MELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDD 477 S A+ + +N + LT + T +D G + + Sbjct: 519 GLSYPDLAKDGQRYTIDNPCKALRLTGCST-TTREDWDVDRDQGKLSPTLAVAVRPGVEW 577 Query: 478 FTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLE 537 L ++++ P++ +T N +S N L+ E S E+G Sbjct: 578 LELYTTYGKSWRPPAITETLTNGSAHSSSTQYP----------NPFLQPERSRAWEVGFN 627 Query: 538 -------FKRDGWLAGVTWFRNDYRNKIEAGYVA----VGQNAVGTDLYQWDNVPKAVVE 586 F+ D +A V +F N I + Q ++G Y +N+ K Sbjct: 628 VQQPDLWFEGDRLVAKVAYFDTKVDNYINLAIDRNKPGLVQPSIGNAAY-VNNLSKTRFR 686 Query: 587 GLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSW----------- 635 GLE LN T+M+ +N+ + + L L + Sbjct: 687 GLEYQLNYDAG-VFYADLTYTHMI-GKNEFCSN------KAWLGGRLRYGDGSRRGNFYV 738 Query: 636 ---QAREDLSMQTTFTWYGK----------------------------QQPKKYNYKGQP 664 A D T +G + Y P Sbjct: 739 EPDAASNDFVTCDGGTQFGSAAYLPGDRGSVTLGGRAFDRKLDAGVTVRFAPGYQDSSVP 798 Query: 665 AVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIA 724 + P + Y++ L A++ +T +++L G V+NL ++ + L + Sbjct: 799 SNYPYLADWPKYTLFDLYASYKLTDSLTLRGSVENLTNRAYVVSYGETLANTLGRGRTVQ 858 Query: 725 GAGAYTY 731 G Y + Sbjct: 859 GGVEYRF 865 >4RDT-A nrPDB Length = 748 Score = 78.9 bits (192), Expect = 8e-15, Method: Composition-based stats. Identities = 119/784 (15%), Positives = 230/784 (29%), Gaps = 127/784 (16%) Query: 19 VAQAQEPTDTPVSHDDTIVVTAAEQ-NLQAPGVSTITADEIRK----NPVARDVSKIIRT 73 V + T+ V + VV + ++ +D+I A ++ + Sbjct: 10 VPRGSHETEQSVDLETVSVVGKSRPRATSGLLHTSTASDKIISGDTLRQKAVNLGDALDG 69 Query: 74 MPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDT 133 +PG++ + G IRG G+ + N + + Sbjct: 70 VPGIHASQYG-----GGASAPVIRGQT---------GRRIKVLNHHGETGDMADFSPDHA 115 Query: 134 SWVPPEMIERIEVLRGPAAARYGNGAAGGVVN-----IITKKGSGEWHGSWDAYFNAPEH 188 V + +++E+LRGP Y +G G+V+ I K G ++ Sbjct: 116 IMVDTALSQQVEILRGPVTLLYSSGNVAGLVDVADGKIPEKMPENGVSGELGLRLSSGNL 175 Query: 189 KEEGATK-RTNFSLTGPLGDEFSFRLYGNLD-KTQADAWDINQGHQSARAGTYATTLPAG 246 ++ + L E +R G+ + + H ++ G+ + G Sbjct: 176 EKLTSGGINIGLGKNFVLHTEGLYRKSGDYAVPRYRNLKRLPDSHADSQTGSIGLSW-VG 234 Query: 247 REGVINKDINGVVRWDFAPLQSLELEAGYS-----------RQGNLYAGDTQNTNSDSYT 295 +G I + P S E + ++ R LY + D Sbjct: 235 EKGFIGVAYSDRRDQYGLPAHSHEYDDCHADIIWQKSLINKRYLQLYPHLLTEEDIDYDN 294 Query: 296 RSK---YGDETNRLYRQNYALTWNGG-WDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKF 351 + D+ N +A T +G W + +YE + P G + Sbjct: 295 PGLSCGFHDDDN-----AHAHTHSGRPWIDLRN----KRYELRAEWKQP--FPGFEALRV 343 Query: 352 NEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNT 411 + D D + +F NQT E Q + L + Sbjct: 344 HLNRNDYRHDEKAGDAVE--------NFFNNQTQNARIELRHQPIGRLKGSWGVQYLQQK 395 Query: 412 GGAIDGVSTTDRSPYSKAEIFSLFAENNMELT--DSTIVTPGLRFD-------------H 456 A+ +S + P ++ +E D+ + G+R + Sbjct: 396 SSALSAISEAVKQPMLLDNKVQHYSFFGVEQANWDNFTLEGGVRVEKQKASIQYDKALID 455 Query: 457 HSIVGNNWSPALNISQGLGDDFTLKMGI------ARAYKAPSLYQTNPNYILYSKGQGCY 510 N+ P L + F L + A + LY+ G+ Sbjct: 456 RENYYNHPLPDLGAHRQTARSFALSGNWYFTPQHKLSLTASHQERLPSTQELYAHGKHVA 515 Query: 511 ASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAV 570 + + GN L E S N E+ L ++ D W + +RN + N I A + G+ Sbjct: 516 TNT---FEVGNKHLNKERSNNIELALGYEGDRWQYNLALYRNRFGNYIYAQTLNDGRGPK 572 Query: 571 GTD------LYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYM---------LKSENK 615 + L ++ N A G EG + + + Y+ L Sbjct: 573 SIEDDSEMKLVRY-NQSGADFYGAEGEIYFKPTPRYRIGVSGDYVRGRLKNLPSLPGRED 631 Query: 616 TTGDR---------LSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAV 666 G+R +P L L + + + Y Q + Sbjct: 632 AYGNRPFIAQDDQNAPRVPAARLGFHLKASLTDRIDANLDY----------YRVFAQNKL 681 Query: 667 GPETKEISPYSIVGLSATWDVTKNVSLT-----GGVDNLFDKRLWRAGNAQTTGDLAGAN 721 + ++ L A + +N DNL ++ ++ + + G + Sbjct: 682 ARYETRTPGHHMLNLGANYR--RNTRYGEWNWYVKADNLLNQSVYAHSSFLSDTPQMGRS 739 Query: 722 YIAG 725 + G Sbjct: 740 FTGG 743 >3DWO-X nrPDB Length = 451 Score = 38.0 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 41/234 (17%), Positives = 82/234 (35%), Gaps = 28/234 (11%) Query: 469 NISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAET 528 ++S + D+F+L G+ + + Q Y + G + G + + Sbjct: 149 SLSFKVNDNFSLGAGVIIQRTSGFVSQNLDLYASAANSPG---------MGGIPFPASNS 199 Query: 529 SINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGL 588 S + ++ G+ AG W D R+ + Y A +N + +D+ + Sbjct: 200 SALMRVKVDNTSPGFFAGAVWKPTD-RDTLGFAYHAKIRNKLKGHYNLYDHDGGLTEGAI 258 Query: 589 EGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSW--QAREDLSMQTT 646 EG + + + M S + IP Y ++L W Q + LS+ + Sbjct: 259 EGG-----TPGLAYPGLDLRMGASASAR-----LDIPAY---ASLDWVHQFNDRLSLGAS 305 Query: 647 FTW--YGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVD 698 TW + Q G V + +++ + + VT ++ GV Sbjct: 306 ATWTEWSSFQDLTLKSHGNTIVSIPYTYRNTWTLA-VGGDYKVTDQWTMRAGVA 358 >5XAO-A nrPDB Length = 445 Score = 35.7 bits (80), Expect = 0.079, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 21/47 (44%) Query: 579 NVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIP 625 N+ K VVE LEG+L ++ W LKS L+ +P Sbjct: 380 NIGKHVVELLEGTLADDLAHAWRWRPGSGDALKSRRSAPAKDLADMP 426 >6ID1-L nrPDB Length = 802 Score = 35.0 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 45/121 (37%), Gaps = 6/121 (4%) Query: 26 TDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSKIIRTMPGVNLTGNSTS 85 +TP+ D VT Q +Q P T N A ++ T P + NST Sbjct: 383 LNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSN-GAEGLTPRSGTTPKPVI--NSTP 439 Query: 86 GQRGNNRQIDIR---GMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE 142 G+ +++I GM + + SR +R G G + D V PE E Sbjct: 440 GRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAE 499 Query: 143 R 143 + Sbjct: 500 K 500 >1GPE-A nrPDB Length = 587 Score = 33.4 bits (74), Expect = 0.39, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 551 RNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYML 610 N+ N I+AG G + D W K ++ E + E W N YM Sbjct: 91 INNRTNNIKAGKGLGGSTLINGD--SWTRPDKVQIDSWEKVFGM---EGWNWDNMFEYMK 145 Query: 611 KSENKTTGDRLSIIPEYTLNST 632 K+E T + ++ N+T Sbjct: 146 KAEAARTPTAAQLAAGHSFNAT 167 >6AGQ-A nrPDB Length = 321 Score = 32.3 bits (71), Expect = 0.78, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 43/139 (30%), Gaps = 15/139 (10%) Query: 553 DYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVE-----------GLEGSLNVPVSETVM 601 DY K + Y V A GT ++ W PK + G G+ P +E + Sbjct: 49 DYPLKSISIYDVVYDGADGTPIHGWYVTPKGEHQPGSLPVLVKYHGYSGNRGYP-NELLQ 107 Query: 602 WTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYK 661 W + L + + G EY W L ++Y KQ Sbjct: 108 WASMGMAALAIDVRGQGGVTPDRAEYPQGGIPGWMTLGILD---PASYYYKQVYLDCIRA 164 Query: 662 GQPAVGPETKEISPYSIVG 680 E + S ++ G Sbjct: 165 LDFVCSREEVDASRIAVYG 183 >1W9D-M nrPDB Length = 501 Score = 32.3 bits (71), Expect = 0.93, Method: Composition-based stats. Identities = 24/197 (12%), Positives = 60/197 (30%), Gaps = 21/197 (10%) Query: 522 DDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAV--GTDLYQWDN 579 E S + +F G+ ++ Y + A+ + N Sbjct: 308 PSFSPEESNLVKGSYDFL------GLNYYFTQYAQPSPNPVNSTNHTAMMDAGAKLTYIN 361 Query: 580 VPKAVVEGLEGSLNVPVSETVMWTNNITYMLKS--ENKTTGDRLSIIPEYTLNSTLSWQA 637 + L ++ + + Y + +NK + L + E +++ + Sbjct: 362 ASGHYIGPLFEKDKADSTDNIYYYPKGIYSVMDYFKNKYY-NPLIYVTENGISTPGD-EN 419 Query: 638 REDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGV 697 R + T Y + + + + Y L ++ K ++ G+ Sbjct: 420 RNQSMLDYTRIDY----LCSHLCFLNKVIKEKDVNVKGYLAWALGDNYEFNKGFTVRFGL 475 Query: 698 -----DNLFDKRLWRAG 709 +N+ D+ L ++G Sbjct: 476 SYIDWNNVTDRDLKKSG 492 >4Q35-A nrPDB Length = 802 Score = 30.7 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 14/107 (13%), Positives = 38/107 (35%), Gaps = 2/107 (1%) Query: 628 TLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDV 687 + + ++ + +D +++ G+ + G + E + + + W + Sbjct: 557 QVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRI 616 Query: 688 TKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEP 734 ++ L GG+ +D RL + ++ + Y Y P Sbjct: 617 SERWGLRGGIQ--YDTRLDNVATSNSSIEYRRDEDRLVQLNYHYASP 661 >4RHB-A nrPDB Length = 614 Score = 30.7 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 14/107 (13%), Positives = 38/107 (35%), Gaps = 2/107 (1%) Query: 628 TLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDV 687 + + ++ + +D +++ G+ + G + E + + + W + Sbjct: 379 QVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRI 438 Query: 688 TKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEP 734 ++ L GG+ +D RL + ++ + Y Y P Sbjct: 439 SERWGLRGGIQ--YDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASP 483 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.299 0.109 0.259 Lambda K H 0.267 0.0335 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,710,885 Number of Sequences: 36641 Number of extensions: 924491 Number of successful extensions: 1984 Number of sequences better than 10.0: 40 Number of HSP's better than 10.0 without gapping: 51 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1727 Number of HSP's gapped (non-prelim): 119 length of query: 746 length of database: 10,336,785 effective HSP length: 104 effective length of query: 642 effective length of database: 6,526,121 effective search space: 4189769682 effective search space used: 4189769682 T: 11 A: 40 X1: 16 ( 6.9 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.3 bits) S2: 62 (28.8 bits)