BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05458 (962 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1Q2L-A nrPDB 1939 0.0 5CIO-A nrPDB 105 9e-23 4NNZ-A nrPDB 66 9e-11 3HDI-A nrPDB 64 2e-10 1HR8-B nrPDB 63 5e-10 1BCC-A nrPDB 62 1e-09 3L72-A nrPDB 57 5e-08 6HAW-A nrPDB 55 2e-07 5XTH-AL nrPDB 54 3e-07 3GO9-A nrPDB 44 4e-04 2FGE-A nrPDB 43 6e-04 5EUF-A nrPDB 42 0.002 3RPN-A nrPDB 33 0.49 3EOQ-A nrPDB 33 0.85 2QUB-A nrPDB 32 1.6 6N9G-C nrPDB 31 2.7 5XJM-A nrPDB 30 5.1 4K3C-A nrPDB 30 5.5 2YL2-A nrPDB 30 5.6 5UNF-A nrPDB 30 6.4 1HR7-A nrPDB 30 6.7 1JQG-A nrPDB 29 9.8 >1Q2L-A nrPDB Length = 939 Score = 1939 bits (5024), Expect = 0.0, Method: Compositional matrix adjust. Identities = 939/939 (100%), Positives = 939/939 (100%) Query: 24 ETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAY 83 ETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAY Sbjct: 1 ETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAY 60 Query: 84 QGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVD 143 QGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVD Sbjct: 61 QGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVD 120 Query: 144 RLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNL 203 RLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNL Sbjct: 121 RLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNL 180 Query: 204 ETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP 263 ETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP Sbjct: 181 ETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP 240 Query: 264 EITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTL 323 EITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTL Sbjct: 241 EITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTL 300 Query: 324 SDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKG 383 SDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKG Sbjct: 301 SDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKG 360 Query: 384 IDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVK 443 IDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVK Sbjct: 361 IDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVK 420 Query: 444 ERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPEL 503 ERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPEL Sbjct: 421 ERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPEL 480 Query: 504 NPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSA 563 NPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSA Sbjct: 481 NPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSA 540 Query: 564 RNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEG 623 RNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEG Sbjct: 541 RNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEG 600 Query: 624 YFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSIT 683 YFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSIT Sbjct: 601 YFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSIT 660 Query: 684 LKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQ 743 LKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQ Sbjct: 661 LKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQ 720 Query: 744 SVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFA 803 SVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFA Sbjct: 721 SVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFA 780 Query: 804 FPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQML 863 FPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQML Sbjct: 781 FPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQML 840 Query: 864 QAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILS 923 QAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILS Sbjct: 841 QAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILS 900 Query: 924 QISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE 962 QISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE Sbjct: 901 QISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE 939 >5CIO-A nrPDB Length = 793 Score = 105 bits (262), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 79/262 (30%), Positives = 129/262 (49%), Gaps = 20/262 (7%) Query: 48 RLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSL 107 +LDNG+ V +S P A + + + + GS + P A+ GLAH LEHM GS + D L Sbjct: 31 QLDNGLAVRAISTPGAEAAAALVRIEAGSFQAPAAWPGLAHLLEHMLFRGSANFSAQDGL 90 Query: 108 AEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVN 167 + + GG NA+T +TAF+ EV D L + RL+D +A P L + +E ++ Sbjct: 91 MGWTQAAGGRLNATTQATQTAFFFEVGADPLAEGLARLSDMLAAPQLAAEAIAQEIEVID 150 Query: 168 AELTMARTRDGMRMAQVSA-------ETINPAHPGSKFSGGNLETLSDKPGNPVQQALKD 220 AE + R DG + + + ++ H GS+ + G SD + +QQAL+ Sbjct: 151 AEYRLLRA-DGETRCEAAQRQMFSGFDALHRFHIGSRAAFG-----SDI--SALQQALRQ 202 Query: 221 FHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIH 280 FH YY A M + + L +L +A G +P+ + PE T+P + Q + Sbjct: 203 FHHHYYRAPNMTLWLQGPQSLEQLHALAQRYGGGLPSGSATPPE-TLPPLAAGQDYTL-- 259 Query: 281 YVPALPRKVLRVEFRIDNNSAK 302 +P P+ LR+ F + + ++ Sbjct: 260 SLPGAPQ--LRLVFTLPHCRSR 279 Score = 32.0 bits (71), Expect = 1.5, Method: Compositional matrix adjust. Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 8/101 (7%) Query: 762 FVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFAFPMSVGRQWGMGFLLQSN 821 F P DE +L ++ P ++ +LR E +GY V G+ F LQS Sbjct: 649 FYPLQSDEAEGRWALRVLARLYAPRYFQRLRVERNVGYVVQCTFHRCTHVEGLLFALQS- 707 Query: 822 DKQPSFLWERYK----AFFPTAEAKLRAMKPDEFAQIQQAV 858 P+F E+ + F +L + E Q QQA+ Sbjct: 708 ---PTFTAEQLRQLTDEFLQQMHHELTHVSVGELEQTQQAL 745 >4NNZ-A nrPDB Length = 439 Score = 65.9 bits (159), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 80/335 (23%), Positives = 145/335 (43%), Gaps = 7/335 (2%) Query: 49 LDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLA 108 LDNG+ V++ D +A +S L +GS + GL+H LEHM GS+K ++ + Sbjct: 12 LDNGLKVIVREDHRAPVVVSQLWYRIGSSYETPGLTGLSHALEHMMFKGSRKLGPGEA-S 70 Query: 109 EYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNA 168 L+ G NA T TA+Y + D LP A++ AD +A L + E + Sbjct: 71 RVLRDLGAEENAFTTDDYTAYYQVLARDRLPVALEMEADRMAHLSLPVDQFKSEIEVIKE 130 Query: 169 ELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSA 228 E + RT D A A+P S + + ++D + L+ ++E +Y+ Sbjct: 131 ERRL-RTDDNPN-ALAFERFKAAAYPASGYHTPTIGWMADLQRMTIDD-LRHWYESWYAP 187 Query: 229 NLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRK 288 N V+ + E+ +A FG +P ++ + + ++ + ++ LP Sbjct: 188 NNATLVVVGDVTADEVKTLAKRYFGEIPWRQLPPARKPLELAEPGERRLKLYVRTQLPNL 247 Query: 289 VLRVEFRIDNNSAKFRS-KTDELITYLIGNRSPGTLSDWLQK-QGLVEGISANSDPIVNG 346 ++ +S R LI L+ L+ L++ + LV G S D G Sbjct: 248 IMGFNVPSLGSSENPREVNALRLIGALLDGGYSARLASRLERGEELVAGASTYYDAFNRG 307 Query: 347 NSGVLAISASLTDKGLANRDQVVAAIFSYLNLLRE 381 +S + +SA+ + +QV A ++ L+ L++ Sbjct: 308 DS-LFVLSATPNVQKGKTLEQVEAGLWKQLDDLKQ 341 >3HDI-A nrPDB Length = 421 Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 62/225 (27%), Positives = 102/225 (45%), Gaps = 16/225 (7%) Query: 46 AIRLDNGMVVLLVSDPQAVKSLSALV-VPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 + LDNG V ++ V+S+S + V GS + G++H+LEHM G+ A Sbjct: 4 TMTLDNG-VRIITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNT-RSA 61 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 +AE+ GG NA T+ T +Y +V +D A+D L+D K+ E+ER Sbjct: 62 QEIAEFFDSIGGQVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEELEKERK 121 Query: 165 AVNAELTMA-RTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQA-LKDFH 222 V E+ M T D + +S+ T G G +ETL N + L+ + Sbjct: 122 VVFEEIKMVDDTPDDIVHDLLSSATYGKHSLGYPIL-GTVETL-----NSFNEGMLRHYM 175 Query: 223 EKYYSANLMKAVIYSNKPLPELAKMAADTFGRVP----NKESKKP 263 +++Y+ + + + N EL +TF +V N + +KP Sbjct: 176 DRFYTGDYVVISVAGNVH-DELIDKIKETFSQVKPTTYNYQGEKP 219 >1HR8-B nrPDB Length = 443 Score = 63.2 bits (152), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 57/220 (25%), Positives = 95/220 (43%), Gaps = 13/220 (5%) Query: 48 RLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSL 107 +L NG+ + P + + V GS + G AH+L+H++ G++ PQ Sbjct: 11 KLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKGTQNRPQQGIE 70 Query: 108 AEYLKMHGGSH-NASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAV 166 E + GSH NA T+ T +Y + + +P AVD L+D + + +LD ERER+ + Sbjct: 71 LEIENI--GSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERDVI 128 Query: 167 NAEL-TMARTRDGMRMAQVSAETINPAHPGSKFSG--GNLETLSDKPGNPVQQALKDFHE 223 E + + D + + T G G N+++++ + LKD+ Sbjct: 129 IRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGPIKNIKSIT-------RTDLKDYIT 181 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP 263 K Y + M +L + A FG VP ES P Sbjct: 182 KNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVP 221 >1BCC-A nrPDB Length = 446 Score = 62.4 bits (150), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 56/216 (25%), Positives = 99/216 (45%), Gaps = 14/216 (6%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 Q +LDNG+ V Q ++ + + GS + E G ++LEH++ G+K PQ Sbjct: 15 QVSQLDNGVRVASEQSSQPTCTV-GVWIDAGSRYESEKNNGAGYFLEHLAFKGTKNRPQ- 72 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 ++L + ++ G NA ++ TA+Y++ + +P AV+ LAD + L+ E+ER+ Sbjct: 73 NALEKEVESMGAHLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNCSLEDSQIEKERD 132 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQA----LKD 220 + EL T M +V N H + F G L + P +++ L + Sbjct: 133 VIVRELQENDT----SMREV---VFNYLH-ATAFQGTGLAQSVEGPSENIRKLSRADLTE 184 Query: 221 FHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVP 256 + +Y+A M +L ++A FG VP Sbjct: 185 YLSTHYTAPRMVLAAAGGVEHQQLLELAQKHFGGVP 220 >3L72-A nrPDB Length = 446 Score = 56.6 bits (135), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 37/122 (30%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Query: 49 LDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLA 108 LDNG+ V Q ++ + + GS + E G +++EH++ G+KK P A Sbjct: 19 LDNGLRVASEESSQPTCTV-GVWIGAGSRYENEKNNGAGYFVEHLAFKGTKKRPCAAFEK 77 Query: 109 EYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNA 168 E M G N T+ +TAFY++ + +P V+ LAD + L++ E+ER + Sbjct: 78 EVESM-GAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNCALEESQIEKERGVILQ 136 Query: 169 EL 170 EL Sbjct: 137 EL 138 >6HAW-A nrPDB Length = 438 Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 36/126 (28%), Positives = 65/126 (51%), Gaps = 2/126 (1%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 Q +LDNG+ V Q ++ + + GS + E G +++EH++ G+K P Sbjct: 14 QVSQLDNGLRVASEQSSQPTCTV-GVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRP-G 71 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 ++L + ++ G NA + TA+Y++ + LP AV+ LAD + L+ E+ER+ Sbjct: 72 NALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERD 131 Query: 165 AVNAEL 170 + EL Sbjct: 132 VILQEL 137 >5XTH-AL nrPDB Length = 446 Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 19/248 (7%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 Q LDNG+ V Q ++ + + VGS + E G ++LEH++ G+K P Sbjct: 15 QVSLLDNGLRVASEQSSQPTCTV-GVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRP-G 72 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 +L + ++ G NA + TA+Y++ + LP AV+ L D + L+ E+ER+ Sbjct: 73 SALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERD 132 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQA----LKD 220 + E M MR N H + F G L + P V++ L + Sbjct: 133 VILRE--MQENDASMRDV-----VFNYLH-ATAFQGTPLAQAVEGPSENVRKLSRADLTE 184 Query: 221 FHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVP--NKESKKPEITVPVVTDAQKGII 278 + +Y A M +L +A G +P E P +T T ++ I Sbjct: 185 YLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSE---I 241 Query: 279 IHYVPALP 286 H ALP Sbjct: 242 RHRDDALP 249 >3GO9-A nrPDB Length = 492 Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 53/225 (23%), Positives = 88/225 (39%), Gaps = 17/225 (7%) Query: 44 YQAIRLDNGMVVLLVSDPQ--AVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKY 101 +Q +LDNG L++ PQ + + L+V GSL + G AH L ++LM S + Sbjct: 26 WQQGKLDNGFSWQLLATPQRPSDRIELRLIVNTGSLSENTQEVGFAHLLPRLALMSSASF 85 Query: 102 PQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALP-GAVDRLADAIAEPLLDKKYAE 160 A + L G + P T++ + + +LP D L DA+A Sbjct: 86 TPAQ--LQSLWQQGIDNERPLPPAITSYDFTLYSLSLPNNRPDLLKDALAWLSDTAGNLA 143 Query: 161 RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQ---- 216 VNA L A ++ N P ++ + PG PV Q Sbjct: 144 VSEQTVNAALNTATD-------PIATFPQNIQEPWWRYRLKGSSLIGHDPGQPVTQPVDV 196 Query: 217 -ALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKES 260 LK F++++Y+ + M + N +A + F + K + Sbjct: 197 EKLKQFYQQWYTPDAMTLYVVGNVDSRSIAAQISKAFSELKGKRT 241 >2FGE-A nrPDB Length = 995 Score = 43.1 bits (100), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 51/207 (24%), Positives = 87/207 (42%), Gaps = 30/207 (14%) Query: 80 PEAYQGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSH---NASTAPYRTAFYLEVEND 136 P+ G+ H L+H L GS+KYP + E LK G H NA T P RT + + N Sbjct: 69 PKDSTGIPHILQHSVLCGSRKYPVKEPFVELLK--GSLHTFLNAFTYPDRTCYPVASTNT 126 Query: 137 A-LPGAVDRLADAIAEP-LLDKKYAERE----------------RNAVNAELTMARTRDG 178 VD DA+ P +D + ++ + V E+ ++ Sbjct: 127 KDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWHYELNDPSEDISYKGVVFNEMKGVYSQPD 186 Query: 179 MRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYS- 237 + +++ + ++P + SGG+ + D P N + K+FH +YY + + Y Sbjct: 187 NILGRIAQQALSPENTYGVDSGGDPK---DIP-NLTFEEFKEFHRQYYHPSNARIWFYGD 242 Query: 238 NKPLPELAKMAA--DTFGRVPNKESKK 262 + P+ L ++ D F P+ S K Sbjct: 243 DDPVHRLRVLSEYLDMFEASPSPNSSK 269 >5EUF-A nrPDB Length = 419 Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust. Identities = 57/245 (23%), Positives = 105/245 (42%), Gaps = 15/245 (6%) Query: 43 QYQAIRLDNGMVVLLVSDPQAVKSLSALVV-PVGSLEDPEAYQGLAHYLEHMSLMGSKKY 101 +++++ L NG+ V+ V + V+ VGS + G+AH LEH++ +K Sbjct: 7 KHESVTLKNGLQVVSVPLENKTGVIEVDVLYKVGSRNEVMGKSGIAHMLEHLNFKSTKNL 66 Query: 102 PQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAER 161 +A + +K GG NAST+ T ++++ L +++ A+ + L + Sbjct: 67 -KAGEFDKIVKRFGGVSNASTSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFLP 125 Query: 162 ERNAVNAELTMARTRDGMRMAQVSAETINPA---HPGSKFSGGNLETLSDKPGNPVQQAL 218 ER V AE RT D + + N A HP G ++ + N + + Sbjct: 126 ERQVV-AEERRWRT-DNSPIGMLYFRFFNTAYVYHPYHWTPIGFMDDIQ----NWTLKDI 179 Query: 219 KDFHEKYYS-ANLMKAVI--YSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQK 275 K FH YY N + V+ +++ + EL K ++ + K P + P D + Sbjct: 180 KKFHSLYYQPKNAIVLVVGDVNSQKVFELTKKHFESLKNLDEKAIPTPYMKEP-KQDGAR 238 Query: 276 GIIIH 280 ++H Sbjct: 239 TAVVH 243 >3RPN-A nrPDB Length = 234 Score = 33.5 bits (75), Expect = 0.49, Method: Compositional matrix adjust. Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 23/114 (20%) Query: 731 WCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQ 790 W RN+D+ + EKAG S + A LL +I P NQ Sbjct: 126 WSRNEDITEPQSILAAAEKAGMSAEQA------------------QGLLEKIATPKVKNQ 167 Query: 791 LR--TEEQLGYAVFAFPMSVGRQWGMGFLLQSNDKQ---PSFLWERYKAFFPTA 839 L+ TE Y F P++V G +L +D+ L E++ P A Sbjct: 168 LKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPA 221 >3EOQ-A nrPDB Length = 406 Score = 32.7 bits (73), Expect = 0.85, Method: Compositional matrix adjust. Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Query: 44 YQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQ 103 ++ L NG+ V+ P A V G+ ++ + G++H+LEHM G + Sbjct: 2 FREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPE---D 58 Query: 104 ADSLA--EYLKMHGGSHNASTAPYRTAFY 130 D+LA G +NA T+ T +Y Sbjct: 59 MDALAVNRAFDRMGAQYNAFTSEEATVYY 87 >2QUB-A nrPDB Length = 615 Score = 31.6 bits (70), Expect = 1.6, Method: Compositional matrix adjust. Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 15/122 (12%) Query: 709 TEAQATTLAR-DVQKQLGADGSEWCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGY 767 T AQA L + D + L A G + ++S+I + G+ + LA F P GY Sbjct: 119 TTAQAEVLGKYDSEGNLTAIGISFRGTSG----PRESLIGDTIGDVINDLLAG-FGPKGY 173 Query: 768 -DEYTSSAYSSLLGQIVQPWFYNQLRTEEQL-------GYAVFAFPMSVGRQWGMGFLLQ 819 D YT A+ +LLG + + + L E+ + G AV + WG GF Q Sbjct: 174 ADGYTLKAFGNLLGDVAKFAQAHGLSGEDVVVSGHSLGGLAVNSMAAQSDANWG-GFYAQ 232 Query: 820 SN 821 SN Sbjct: 233 SN 234 >6N9G-C nrPDB Length = 353 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 2/59 (3%) Query: 734 NKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLR 792 +++V + K+S+IF +S D +L+ + GY++YT + + L G V F ++ R Sbjct: 271 DREVAIYSKESIIF--GASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENR 327 >5XJM-A nrPDB Length = 422 Score = 30.0 bits (66), Expect = 5.1, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 12/86 (13%) Query: 739 VDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQ-LRTEEQL 797 VD+ QSVI+ + A+ VP + + SSL P FY + +RT E L Sbjct: 107 VDRYQSVIYPFLSQRRNPWQASYIVPL---VWCMACLSSL------PTFYFRDVRTIEYL 157 Query: 798 GY--AVFAFPMSVGRQWGMGFLLQSN 821 G + AFP QW G L N Sbjct: 158 GVNACIMAFPPEKYAQWSAGIALMKN 183 >4K3C-A nrPDB Length = 532 Score = 30.0 bits (66), Expect = 5.5, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 10/78 (12%) Query: 458 YISPKEPHN-KTAYFVDAPY---------QVDKISAQTFADWQKKAADIALSLPELNPYI 507 +IS K HN +T+ FVDA + D + F D+++ A ++L +P Sbjct: 444 FISDKYQHNVRTSVFVDAATVWNTKWKQSKADYPNLPDFGDYKRVRASAGIALQWQSPIG 503 Query: 508 PDDFSLIKSEKKYDHPEL 525 P FS K KKY E+ Sbjct: 504 PLSFSYAKPIKKYAGDEI 521 >2YL2-A nrPDB Length = 540 Score = 30.0 bits (66), Expect = 5.6, Method: Compositional matrix adjust. Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 16/139 (11%) Query: 520 YDHPELIVDESN---LRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQVMFALNDYLA 576 Y + ELI+D + ++ V+A + + PK L+L+N A +Q M+AL D +A Sbjct: 110 YANVELILDIAKRIPVQAVWAGWGHASENPKLP-ELLLKNGIAFMGPPSQAMWALGDKIA 168 Query: 577 GLALDQLSNQASVGGISFSTNANNGLMVN--ANGYTQRLPQLFQALLE-GYFSYTATEDQ 633 S A GI + +GL V+ N +++R+ + Q L E GY +D Sbjct: 169 S------SIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVK--DVDDG 220 Query: 634 LEQAKS-WYNQMMDSAEKG 651 L+ A+ Y M+ ++E G Sbjct: 221 LQAAEEVGYPVMIKASEGG 239 >5UNF-A nrPDB Length = 411 Score = 29.6 bits (65), Expect = 6.4, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 37/86 (43%), Gaps = 12/86 (13%) Query: 739 VDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQ-LRTEEQL 797 VD+ QSVI+ + A+ VP + + SSL P FY + +RT E L Sbjct: 216 VDRYQSVIYPFLSQRRNPWQASYIVPL---VWCMACLSSL------PTFYFRDVRTIEYL 266 Query: 798 GY--AVFAFPMSVGRQWGMGFLLQSN 821 G + AFP QW G L N Sbjct: 267 GVNACIMAFPPEKYAQWSAGIALMKN 292 >1HR7-A nrPDB Length = 475 Score = 29.6 bits (65), Expect = 6.7, Method: Compositional matrix adjust. Identities = 22/122 (18%), Positives = 58/122 (47%), Gaps = 2/122 (1%) Query: 49 LDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLA 108 L NG+ V + P +L L + GS + +G H L+ ++ S ++ + ++A Sbjct: 11 LANGLKVATSNTPGHFSAL-GLYIDAGSRFEGRNLKGCTHILDRLAFK-STEHVEGRAMA 68 Query: 109 EYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNA 168 E L++ GG++ +++ + V N + + +++ + P + ++ + ++ + Sbjct: 69 ETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEY 128 Query: 169 EL 170 E+ Sbjct: 129 EI 130 >1JQG-A nrPDB Length = 433 Score = 29.3 bits (64), Expect = 9.8, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 720 VQKQLGADGSEWCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLL 779 VQ D +W NKD +V V++ +G ++D A+ A P Y Y AY + + Sbjct: 333 VQMAQAIDRVKWSSNKDYIVGNIFHVLYAASGGASDYAMQAA-APFSY-TYELPAYRNSV 390 Query: 780 ---GQIVQPWFYNQLRTEEQLGYAV 801 G +V P F Q E G V Sbjct: 391 WFDGFLVDPDFIEQAGFETWEGIKV 415 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1Q2L-A nrPDB 1737 0.0 4NNZ-A nrPDB 380 e-105 5XTH-AL nrPDB 255 7e-68 1BCC-A nrPDB 253 3e-67 6HAW-A nrPDB 247 2e-65 5CIO-A nrPDB 243 2e-64 1HR8-B nrPDB 229 5e-60 5EUF-A nrPDB 229 6e-60 3L72-A nrPDB 221 1e-57 3HDI-A nrPDB 219 4e-57 3GO9-A nrPDB 204 1e-52 2FGE-A nrPDB 161 1e-39 Sequences not found previously or not previously below threshold: 3EOQ-A nrPDB 143 3e-34 1HR7-A nrPDB 99 7e-21 6GIQ-A nrPDB 74 3e-13 3L73-B nrPDB 73 6e-13 5GUP-v nrPDB 69 7e-12 6HAW-B nrPDB 69 9e-12 2BCC-B nrPDB 69 1e-11 5XTH-AK nrPDB 64 3e-10 3CX5-B nrPDB 62 2e-09 6F73-A nrPDB 36 0.067 3RPN-A nrPDB 36 0.076 3JCM-G nrPDB 36 0.11 5OVN-B nrPDB 35 0.14 5OVN-A nrPDB 35 0.14 2QUB-A nrPDB 34 0.25 3SC7-X nrPDB 34 0.36 2YL2-A nrPDB 34 0.43 4K3C-A nrPDB 33 0.82 1Q90-A nrPDB 32 0.91 1E2W-A nrPDB 32 0.91 6N9G-C nrPDB 32 1.5 5XJM-A nrPDB 32 1.7 5UNF-A nrPDB 32 1.7 5MRE-88 nrPDB 32 1.8 1FNN-A nrPDB 31 1.9 2FYO-A nrPDB 31 2.1 2GQQ-A nrPDB 31 2.5 2K7H-A nrPDB 30 4.1 6FSZ-KK nrPDB 30 5.1 5K36-J nrPDB 30 5.1 3UEK-A nrPDB 30 6.2 >1Q2L-A nrPDB Length = 939 Score = 1737 bits (4499), Expect = 0.0, Method: Composition-based stats. Identities = 939/939 (100%), Positives = 939/939 (100%) Query: 24 ETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAY 83 ETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAY Sbjct: 1 ETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAY 60 Query: 84 QGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVD 143 QGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVD Sbjct: 61 QGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVD 120 Query: 144 RLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNL 203 RLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNL Sbjct: 121 RLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNL 180 Query: 204 ETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP 263 ETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP Sbjct: 181 ETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP 240 Query: 264 EITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTL 323 EITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTL Sbjct: 241 EITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTL 300 Query: 324 SDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKG 383 SDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKG Sbjct: 301 SDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKG 360 Query: 384 IDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVK 443 IDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVK Sbjct: 361 IDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVK 420 Query: 444 ERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPEL 503 ERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPEL Sbjct: 421 ERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPEL 480 Query: 504 NPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSA 563 NPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSA Sbjct: 481 NPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSA 540 Query: 564 RNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEG 623 RNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEG Sbjct: 541 RNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEG 600 Query: 624 YFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSIT 683 YFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSIT Sbjct: 601 YFSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSIT 660 Query: 684 LKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQ 743 LKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQ Sbjct: 661 LKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVDKKQ 720 Query: 744 SVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFA 803 SVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFA Sbjct: 721 SVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFA 780 Query: 804 FPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQML 863 FPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQML Sbjct: 781 FPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQML 840 Query: 864 QAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILS 923 QAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILS Sbjct: 841 QAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILS 900 Query: 924 QISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE 962 QISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE Sbjct: 901 QISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE 939 >4NNZ-A nrPDB Length = 439 Score = 380 bits (976), Expect = e-105, Method: Composition-based stats. Identities = 80/335 (23%), Positives = 145/335 (43%), Gaps = 7/335 (2%) Query: 49 LDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLA 108 LDNG+ V++ D +A +S L +GS + GL+H LEHM GS+K ++ + Sbjct: 12 LDNGLKVIVREDHRAPVVVSQLWYRIGSSYETPGLTGLSHALEHMMFKGSRKLGPGEA-S 70 Query: 109 EYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNA 168 L+ G NA T TA+Y + D LP A++ AD +A L + E + Sbjct: 71 RVLRDLGAEENAFTTDDYTAYYQVLARDRLPVALEMEADRMAHLSLPVDQFKSEIEVIKE 130 Query: 169 ELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSA 228 E + RT D A A+P S + + ++D + L+ ++E +Y+ Sbjct: 131 ERRL-RTDDNPN-ALAFERFKAAAYPASGYHTPTIGWMADLQRMTI-DDLRHWYESWYAP 187 Query: 229 NLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRK 288 N V+ + E+ +A FG +P ++ + + ++ + ++ LP Sbjct: 188 NNATLVVVGDVTADEVKTLAKRYFGEIPWRQLPPARKPLELAEPGERRLKLYVRTQLPNL 247 Query: 289 VLRVEFRIDNNSAKFRS-KTDELITYLIGNRSPGTLSDWLQK-QGLVEGISANSDPIVNG 346 ++ +S R LI L+ L+ L++ + LV G S D G Sbjct: 248 IMGFNVPSLGSSENPREVNALRLIGALLDGGYSARLASRLERGEELVAGASTYYDAFNRG 307 Query: 347 NSGVLAISASLTDKGLANRDQVVAAIFSYLNLLRE 381 +S + +SA+ + +QV A ++ L+ L++ Sbjct: 308 DS-LFVLSATPNVQKGKTLEQVEAGLWKQLDDLKQ 341 >5XTH-AL nrPDB Length = 446 Score = 255 bits (651), Expect = 7e-68, Method: Composition-based stats. Identities = 62/278 (22%), Positives = 111/278 (39%), Gaps = 20/278 (7%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 Q LDNG+ V Q ++ + + VGS + E G ++LEH++ G+K P Sbjct: 15 QVSLLDNGLRVASEQSSQPTCTV-GVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRP-G 72 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 +L + ++ G NA + TA+Y++ + LP AV+ L D + L+ E+ER+ Sbjct: 73 SALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERD 132 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQ----ALKD 220 + E+ + N H + F G L + P V++ L + Sbjct: 133 VILREMQENDAS-------MRDVVFNYLH-ATAFQGTPLAQAVEGPSENVRKLSRADLTE 184 Query: 221 FHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPN--KESKKPEITVPVVTDAQKGII 278 + +Y A M +L +A G +P E P +T T ++ I Sbjct: 185 YLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSE---I 241 Query: 279 IHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIG 316 H ALP + + ++ + ++ +IG Sbjct: 242 RHRDDALPFAHVAIAVEGPGWAS-PDNVALQVANAIIG 278 >1BCC-A nrPDB Length = 446 Score = 253 bits (646), Expect = 3e-67, Method: Composition-based stats. Identities = 64/278 (23%), Positives = 116/278 (41%), Gaps = 20/278 (7%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 Q +LDNG+ V Q ++ + + GS + E G ++LEH++ G+K PQ Sbjct: 15 QVSQLDNGVRVASEQSSQPTCTV-GVWIDAGSRYESEKNNGAGYFLEHLAFKGTKNRPQ- 72 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 ++L + ++ G NA ++ TA+Y++ + +P AV+ LAD + L+ E+ER+ Sbjct: 73 NALEKEVESMGAHLNAYSSREHTAYYIKALSKDVPKAVELLADIVQNCSLEDSQIEKERD 132 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQ----ALKD 220 + EL T + N H + F G L + P +++ L + Sbjct: 133 VIVRELQENDTS-------MREVVFNYLH-ATAFQGTGLAQSVEGPSENIRKLSRADLTE 184 Query: 221 FHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVP--NKESKKPEITVPVVTDAQKGII 278 + +Y+A M +L ++A FG VP + P ++ T +Q I Sbjct: 185 YLSTHYTAPRMVLAAAGGVEHQQLLELAQKHFGGVPFTYDDDAVPTLSKCRFTGSQ---I 241 Query: 279 IHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIG 316 H LP + + A ++ +IG Sbjct: 242 RHREDGLPLAHVAIAVEGPG-WAHPDLVALQVANAIIG 278 >6HAW-A nrPDB Length = 438 Score = 247 bits (630), Expect = 2e-65, Method: Composition-based stats. Identities = 62/276 (22%), Positives = 112/276 (40%), Gaps = 22/276 (7%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 Q +LDNG+ V Q ++ + + GS + E G +++EH++ G+K P Sbjct: 14 QVSQLDNGLRVASEQSSQPTCTV-GVWIDAGSRYESEKNNGAGYFVEHLAFKGTKNRP-G 71 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 ++L + ++ G NA + TA+Y++ + LP AV+ LAD + L+ E+ER+ Sbjct: 72 NALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERD 131 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQ----ALKD 220 + EL T + N H + F G L + P V++ L + Sbjct: 132 VILQELQENDTS-------MRDVVFNYLH-ATAFQGTPLAQSVEGPSENVRKLSRADLTE 183 Query: 221 FHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIH 280 + ++Y A M +L +A F + S P ++ T +Q I H Sbjct: 184 YLSRHYKAPRMVLAAAGGLEHRQLLDLAQKHFSGL----SGVPTLSPCRFTGSQ---ICH 236 Query: 281 YVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIG 316 LP + + A + ++ +IG Sbjct: 237 REDGLPLAHVAIAVEGPG-WAHPDNVALQVANAIIG 271 >5CIO-A nrPDB Length = 793 Score = 243 bits (621), Expect = 2e-64, Method: Composition-based stats. Identities = 95/361 (26%), Positives = 164/361 (45%), Gaps = 37/361 (10%) Query: 48 RLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSL 107 +LDNG+ V +S P A + + + + GS + P A+ GLAH LEHM GS + D L Sbjct: 31 QLDNGLAVRAISTPGAEAAAALVRIEAGSFQAPAAWPGLAHLLEHMLFRGSANFSAQDGL 90 Query: 108 AEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVN 167 + + GG NA+T +TAF+ EV D L + RL+D +A P L + +E ++ Sbjct: 91 MGWTQAAGGRLNATTQATQTAFFFEVGADPLAEGLARLSDMLAAPQLAAEAIAQEIEVID 150 Query: 168 AELTMARTRDGMRMAQVSAE-------TINPAHPGSKFSGGNLETLSDKPGNPVQQALKD 220 AE + R DG + + ++ H GS+ + G+ + +QQAL+ Sbjct: 151 AEYRLLRA-DGETRCEAAQRQMFSGFDALHRFHIGSRAAFGS-------DISALQQALRQ 202 Query: 221 FHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIH 280 FH YY A M + + L +L +A G +P+ + PE T+P + Q + Sbjct: 203 FHHHYYRAPNMTLWLQGPQSLEQLHALAQRYGGGLPSGSATPPE-TLPPLAAGQDYTL-- 259 Query: 281 YVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVEGISANS 340 +P P+ LR+ F + + ++ + L+ + +PG L L+ A Sbjct: 260 SLPGAPQ--LRLVFTLPHCRSR---GWLRRLERLLLDDAPGGLLARLR-------AHAWG 307 Query: 341 DPIVNG------NSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDK-QYFDELA 393 D + G NS +L+ ++ + + +A+ ++L L + +F +LA Sbjct: 308 DAVRLGYARCGENSALLSFIFTVNHGSASEAAHIESALLAWLQALNALTPGQLAHFGQLA 367 Query: 394 N 394 N Sbjct: 368 N 368 Score = 35.9 bits (81), Expect = 0.081, Method: Composition-based stats. Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 9/107 (8%) Query: 762 FVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYAVFAFPMSVGRQWGMGFLLQSN 821 F P DE +L ++ P ++ +LR E +GY V G+ F LQS Sbjct: 649 FYPLQSDEAEGRWALRVLARLYAPRYFQRLRVERNVGYVVQCTFHRCTHVEGLLFALQS- 707 Query: 822 DKQPSFLWERYKA----FFPTAEAKLRAMKPDEFAQIQQAVITQMLQ 864 P+F E+ + F +L + E Q QQA + Q LQ Sbjct: 708 ---PTFTAEQLRQLTDEFLQQMHHELTHVSVGELEQTQQA-LQQNLQ 750 >1HR8-B nrPDB Length = 443 Score = 229 bits (583), Expect = 5e-60, Method: Composition-based stats. Identities = 58/244 (23%), Positives = 99/244 (40%), Gaps = 11/244 (4%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 + +L NG+ + P + + V GS + G AH+L+H++ G++ PQ Sbjct: 8 RTSKLPNGLTIATEYIPNTSSATVGIFVDAGSRAENVKNNGTAHFLQHLAFKGTQNRPQQ 67 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 E G NA T+ T +Y + + +P AVD L+D + + +LD ERER+ Sbjct: 68 GIELEIEN-IGSHLNAYTSRENTVYYAKSLQEDIPKAVDILSDILTKSVLDNSAIERERD 126 Query: 165 AVNAE-LTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHE 223 + E + + D + + T G G ++ + + LKD+ Sbjct: 127 VIIRESEEVDKMYDEVVFDHLHEITYKDQPLGRTILGP-IKNIKSI----TRTDLKDYIT 181 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKK----PEITVPVVTDAQKGIII 279 K Y + M +L + A FG VP ES P +PV ++ I Sbjct: 182 KNYKGDRMVLAGAGAVDHEKLVQYAQKYFGHVPKSESPVPLGSPRGPLPVFCRGERFIKE 241 Query: 280 HYVP 283 + +P Sbjct: 242 NTLP 245 >5EUF-A nrPDB Length = 419 Score = 229 bits (583), Expect = 6e-60, Method: Composition-based stats. Identities = 74/385 (19%), Positives = 149/385 (38%), Gaps = 19/385 (4%) Query: 43 QYQAIRLDNGMVVLLVSDPQAVKSLSALV-VPVGSLEDPEAYQGLAHYLEHMSLMGSKKY 101 +++++ L NG+ V+ V + V VGS + G+AH LEH++ +K Sbjct: 7 KHESVTLKNGLQVVSVPLENKTGVIEVDVLYKVGSRNEVMGKSGIAHMLEHLNFKSTKNL 66 Query: 102 PQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAER 161 +A + +K GG NAST+ T ++++ L +++ A+ + L + Sbjct: 67 -KAGEFDKIVKRFGGVSNASTSFDITRYFIKTSEANLDKSLELFAETMGSLNLKEDEFLP 125 Query: 162 ERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDF 221 ER V AE RT D + + N A+ + + + D N + +K F Sbjct: 126 ERQVV-AEERRWRT-DNSPIGMLYFRFFNTAYVYHPYHWTPIGFMDDIQ-NWTLKDIKKF 182 Query: 222 HEKYYSANLMKAVIYSNK---PLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGII 278 H YY ++ + + EL K ++ + K P + P D + + Sbjct: 183 HSLYYQPKNAIVLVVGDVNSQKVFELTKKHFESLKNLDEKAIPTPYMKEP-KQDGARTAV 241 Query: 279 IHYV-PALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWL-QKQGLVEGI 336 +H L L + + + + ++ L+G L L K+ L Sbjct: 242 VHKDGVHLEWVALGYKVPAFKHKDQV---ALDALSKLLGEGKSSWLQSELVDKKRLASQA 298 Query: 337 SANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDELANVL 396 +++ + + + + + K A + ++VA L L++ I + D++ Sbjct: 299 FSHNMQLQDESVFLFIAGGNPNIKAEALQKEIVA----LLEKLKKGEITQAELDKIKINQ 354 Query: 397 DIDFRYPSITRDMDYVEWLADTMIR 421 DF ++ D AD +++ Sbjct: 355 KADF-ISNLESSSDVAGLFADYLVQ 378 >3L72-A nrPDB Length = 446 Score = 221 bits (563), Expect = 1e-57, Method: Composition-based stats. Identities = 63/319 (19%), Positives = 114/319 (35%), Gaps = 27/319 (8%) Query: 46 AIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQAD 105 LDNG+ V Q ++ + + GS + E G +++EH++ G+KK P A Sbjct: 16 VTTLDNGLRVASEESSQPTCTV-GVWIGAGSRYENEKNNGAGYFVEHLAFKGTKKRPCA- 73 Query: 106 SLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNA 165 + + ++ G N T+ +TAFY++ + +P V+ LAD + L++ E+ER Sbjct: 74 AFEKEVESMGAHFNGYTSREQTAFYIKALSKDMPKVVELLADVVQNCALEESQIEKERGV 133 Query: 166 VNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPV----QQALKDF 221 + EL T + H + F G L + + + L + Sbjct: 134 ILQELKEMDNDMTNV-------TFDYLH-ATAFQGTALARTVEGTTENIKHLTRADLASY 185 Query: 222 HEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVP--NKESKKPEITVPVVTDAQKGIII 279 + ++ A M EL A F V KE P + T ++ I Sbjct: 186 IDTHFKAPRMVLAAAGGISHKELVDAARQHFSGVSFTYKEDAVPILPRCRFTGSE---IR 242 Query: 280 HYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGN-----RSPGTLSDWLQKQGLVE 334 ALP + + A + + +IG LS L + Sbjct: 243 ARDDALPVAHVALAVEGPG-WADPDNVVLHVANAIIGRYDRTFGGGKHLSSRLAALAVEH 301 Query: 335 GISANSDPIVN--GNSGVL 351 + + ++G+ Sbjct: 302 KLCHSFQTFNTSYSDTGLF 320 >3HDI-A nrPDB Length = 421 Score = 219 bits (558), Expect = 4e-57, Method: Composition-based stats. Identities = 83/356 (23%), Positives = 141/356 (39%), Gaps = 33/356 (9%) Query: 46 AIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQAD 105 + LDNG+ ++ + V GS + G++H+LEHM G+ A Sbjct: 4 TMTLDNGVRIITEKMSTVRSVSIGIWVGTGSRYESAEENGISHFLEHMFFKGTNTRS-AQ 62 Query: 106 SLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNA 165 +AE+ GG NA T+ T +Y +V +D A+D L+D K+ E+ER Sbjct: 63 EIAEFFDSIGGQVNAFTSKEYTCYYAKVLDDHAGQAIDTLSDMFFHSTFQKEELEKERKV 122 Query: 166 VNAELTMA-RTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQA-LKDFHE 223 V E+ M T D + +S+ T G G +ETL N + L+ + + Sbjct: 123 VFEEIKMVDDTPDDIVHDLLSSATYGKHSLGYPIL-GTVETL-----NSFNEGMLRHYMD 176 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTFGRVP----NKESKKPEITVPVVTDAQKGIII 279 ++Y+ + + + N EL +TF +V N + +KP + ++ Sbjct: 177 RFYTGDYVVISVAGNV-HDELIDKIKETFSQVKPTTYNYQGEKPMFLPNRIVRKKETEQA 235 Query: 280 HYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTL-SDWLQKQGLVEGISA 338 H P + L+ ++G L D +K+GL + + Sbjct: 236 HLCLGYPGLPIG----------DKDVYALVLLNNVLGGSMSSRLFQDIREKRGLCYSVFS 285 Query: 339 NSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDELAN 394 +SG+L I A G D +V +I + L EKG+ ++ EL N Sbjct: 286 YHSSFR--DSGMLTIYAG---TGHDQLDDLVYSIQETTSALAEKGLTEK---ELEN 333 >3GO9-A nrPDB Length = 492 Score = 204 bits (520), Expect = 1e-52, Method: Composition-based stats. Identities = 54/238 (22%), Positives = 91/238 (38%), Gaps = 21/238 (8%) Query: 44 YQAIRLDNGMVVLLVSDPQ--AVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKY 101 +Q +LDNG L++ PQ + + L+V GSL + G AH L ++LM S + Sbjct: 26 WQQGKLDNGFSWQLLATPQRPSDRIELRLIVNTGSLSENTQEVGFAHLLPRLALMSSASF 85 Query: 102 PQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPG-AVDRLADAIAEPLLDKKYAE 160 A + L G + P T++ + + +LP D L DA+A Sbjct: 86 TPAQ--LQSLWQQGIDNERPLPPAITSYDFTLYSLSLPNNRPDLLKDALAWLSDTAGNLA 143 Query: 161 RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQ---- 216 VNA L A ++ N P ++ + PG PV Q Sbjct: 144 VSEQTVNAALNTAT-------DPIATFPQNIQEPWWRYRLKGSSLIGHDPGQPVTQPVDV 196 Query: 217 -ALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEI----TVPV 269 LK F++++Y+ + M + N +A + F + K + + +P Sbjct: 197 EKLKQFYQQWYTPDAMTLYVVGNVDSRSIAAQISKAFSELKGKRTAPAAVATLAPLPP 254 >2FGE-A nrPDB Length = 995 Score = 161 bits (408), Expect = 1e-39, Method: Composition-based stats. Identities = 80/383 (20%), Positives = 141/383 (36%), Gaps = 48/383 (12%) Query: 50 DNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLAE 109 G V+ VS+ K + P+ G+ H L+H L GS+KYP + E Sbjct: 44 KTGCEVMSVSNEDENKVFGVVF-----RTPPKDSTGIPHILQHSVLCGSRKYPVKEPFVE 98 Query: 110 YLK-MHGGSHNASTAPYRTAFYLEVEN-DALPGAVDRLADAIAEP-LLDKKYAERE---- 162 LK NA T P RT + + N VD DA+ P +D + ++ Sbjct: 99 LLKGSLHTFLNAFTYPDRTCYPVASTNTKDFYNLVDVYLDAVFFPKCVDDAHTFQQEGWH 158 Query: 163 ------------RNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKP 210 + V E+ ++ + +++ + ++P + SGG+ + + Sbjct: 159 YELNDPSEDISYKGVVFNEMKGVYSQPDNILGRIAQQALSPENTYGVDSGGDPKDI---- 214 Query: 211 GNPVQQALKDFHEKYYSANLMKAVIYS-NKPLPELAKMAA--DTFGRVPNKESKK---PE 264 N + K+FH +YY + + Y + P+ L ++ D F P+ S K + Sbjct: 215 PNLTFEEFKEFHRQYYHPSNARIWFYGDDDPVHRLRVLSEYLDMFEASPSPNSSKIKFQK 274 Query: 265 ITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLS 324 + V +K + +L V + + S K +L + + GT + Sbjct: 275 LFSEPVRLVEKYPAGRDGDLKKKHMLCVNWLL---SEKPLDLQTQLALGFLDHLMLGTPA 331 Query: 325 DWLQKQGLVEGI------SANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNL 378 L+K L G+ S SD ++ G+ S N +V I L Sbjct: 332 SPLRKILLESGLGEALVSSGLSDELLQPQFGIGLKGVSE-----ENVQKVEELIMDTLKK 386 Query: 379 LREKGIDKQYFDELANVLDIDFR 401 L E+G D + N ++ R Sbjct: 387 LAEEGFDNDAVEASMNTIEFSLR 409 >3EOQ-A nrPDB Length = 406 Score = 143 bits (361), Expect = 3e-34, Method: Composition-based stats. Identities = 62/341 (18%), Positives = 120/341 (35%), Gaps = 26/341 (7%) Query: 44 YQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQ 103 ++ L NG+ V+ P A V G+ ++ + G++H+LEHM G + Sbjct: 2 FREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDM-D 60 Query: 104 ADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERER 163 A ++ G +NA T+ T +Y V + + A + P L ++ + E+ Sbjct: 61 ALAVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLL-RPALREEDFQTEK 119 Query: 164 NAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHE 223 + E+ + R G + + HP G E+++ ++ + +H Sbjct: 120 LVILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITAL----TREGMAAYHR 175 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVV-----TDAQKGII 278 + Y M L A P E+++ + +K Sbjct: 176 RRYLPKNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLTPAFGVEERPYEKARA 235 Query: 279 IHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVEGISA 338 ++ V P + E R +++ +L+G G L L +GL E S Sbjct: 236 LYLVALFPGVAYQEEARFPG----------QVLAHLLGEEGSGRLHFALVDKGLAEVASF 285 Query: 339 NSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLL 379 + + + A KG +V+A + L+ L Sbjct: 286 GLEEADRAGTFHAYVQADPARKG-----EVLAVLQEELDRL 321 >1HR7-A nrPDB Length = 475 Score = 99.4 bits (246), Expect = 7e-21, Method: Composition-based stats. Identities = 53/345 (15%), Positives = 124/345 (35%), Gaps = 33/345 (9%) Query: 44 YQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQ 103 ++ L NG+ V + P +L L + GS + +G H L+ ++ ++ + Sbjct: 6 FKLSSLANGLKVATSNTPGHFSAL-GLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHV-E 63 Query: 104 ADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERER 163 ++AE L++ GG++ +++ + V N + + +++ + P + ++ + ++ Sbjct: 64 GRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQK 123 Query: 164 NAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHE 223 + E+ + + + ++ ++ A + G L + + L D+ Sbjct: 124 LSAEYEIDEVWMKPELVLPEL----LHTAAYSGETLGSPLICPRGLIPSISKYYLLDYRN 179 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKP-EITVPVVTDAQKGI----I 278 K+Y+ A P + ++ G + + P V T + I + Sbjct: 180 KFYTPENTVAAFVG-VPHEKALELTGKYLG--DWQSTHPPITKKVAQYTGGESCIPPAPV 236 Query: 279 IHYVPALPRKVLRVE-FRIDNNSAKFRSKTDELITYLIG------------NRSPGTLSD 325 +P L + E ID+ + L+G + Sbjct: 237 FGNLPELFHIQIGFEGLPIDH----PDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTH 292 Query: 326 WLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVA 370 L + VE A + +SG+ IS S + +V+A Sbjct: 293 VLNQYYFVENCVAFNHSY--SDSGIFGISLSCIPQAAPQAVEVIA 335 >6GIQ-A nrPDB Length = 457 Score = 73.6 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 43/347 (12%), Positives = 109/347 (31%), Gaps = 31/347 (8%) Query: 43 QYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP 102 + + +L NG+VV +P A + +V G+ + G+++ +++ L Sbjct: 26 KAEVTQLSNGIVVATEHNPSAHTASVGVVFGSGAANENPYNNGVSNLWKNIFLSKENSAV 85 Query: 103 QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAI---AEPLLDKKYA 159 A G + +++ + ++ + + ++D L + LL Sbjct: 86 AAKE--------GLALSSNISRDFQSYIVSSLPGSTDKSLDFLNQSFIQQKANLLSSSNF 137 Query: 160 ERERNAVNAELT--MARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQA 217 E + +V ++ + + + G + N V Sbjct: 138 EATKKSVLKQVQDFEENDHPNRVLEHLHSTAFQNTPLSLPTRGT-----LESLENLVVAD 192 Query: 218 LKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGI 277 L+ F ++ + V N +L + + KP + + Sbjct: 193 LESFANNHFLNSNAVVVGTGNIKHEDLVNSIES--KNLSLQTGTKPVLKKKAAFLGSE-- 248 Query: 278 IIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVEGIS 337 + LP+ + + + ++ +L + G+ + + LQ L++ I Sbjct: 249 VRLRDDTLPKAWISLAVEGEPVNS-PNYFVAKLAAQIFGSYNAFEPASRLQGIKLLDNIQ 307 Query: 338 ANS--DPIVN-----GNSGVLAIS-ASLTDKGLANRDQVVAAIFSYL 376 D + +SG+ S A+ + + ++ L Sbjct: 308 EYQLCDNFNHFSLSYKDSGLWGFSTATRNVTMIDDLIHFTLKQWNRL 354 >3L73-B nrPDB Length = 441 Score = 72.9 bits (177), Expect = 6e-13, Method: Composition-based stats. Identities = 47/361 (13%), Positives = 116/361 (32%), Gaps = 30/361 (8%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 + +L NG+++ + + + + + GS + A G AH L ++ + K + Sbjct: 27 EITKLPNGLIIASLENFSPASRI-GVFIKAGSRYETTANLGTAHLL-RLASPLTTKGASS 84 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 + ++ GGS + + + + +E D + ++ L + P R Sbjct: 85 FRITRGIEAVGGSLSVYSTREKMTYCVECLRDHVDTVMEYLLNVTTAPEF------RPWE 138 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKP-GNPVQQALKDFHE 223 + + + + + N K + N D G + L F + Sbjct: 139 VTDLQPQLKVDKAVAFQSPQVGVLENLHAAAYKTALANPLYCPDYRIGKITSEQLHHFVQ 198 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVP 283 +++ M V +L ++A + + T + + Sbjct: 199 NNFTSARMALVGIG-VKHSDLKQVAEQFLNIRSGAGTSSAKAT---YWGGEIREQNGH-- 252 Query: 284 ALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNR----SPGTLSDWLQKQGLVEGISAN 339 V + ++ +++G +++ L QG+ + + Sbjct: 253 ---SLVHAAVVTEGAAVGSAEANAFSVLQHVLGAGPLIKRGSSVTSKLY-QGVAKATTQP 308 Query: 340 SDP----IVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDELANV 395 D + +SG+ T A+ +V+ A + L + G+ ++ + N Sbjct: 309 FDASAFNVNYSDSGLFGFY---TISQAAHAGEVIRAAMNQLKAAAQGGVTEEDVTKAKNQ 365 Query: 396 L 396 L Sbjct: 366 L 366 >5GUP-v nrPDB Length = 453 Score = 69.4 bits (168), Expect = 7e-12, Method: Composition-based stats. Identities = 32/209 (15%), Positives = 75/209 (35%), Gaps = 10/209 (4%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 + RL NG+V+ + + A S L + GS + G +H L ++ + K + Sbjct: 39 EFTRLPNGLVIASLENY-APASRIGLFIKAGSRYEDSNNLGTSHLL-RLASSLTTKGASS 96 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 + ++ GG + ++ A+ +E D + ++ L + A P + Sbjct: 97 FKITRGIEAVGGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVA---- 152 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFH-E 223 A+ ++L + + + N + + N D V ++ + Sbjct: 153 ALQSQLRIDKAVAFQN--PQAQVLENLHAAAYRNALANSLYCPDYRIGKVTPDQLHYYVQ 210 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTF 252 ++++ M + P L ++A Sbjct: 211 NHFTSARMALIGLG-VSHPVLKQVAERFL 238 >6HAW-B nrPDB Length = 413 Score = 69.0 bits (167), Expect = 9e-12, Method: Composition-based stats. Identities = 33/209 (15%), Positives = 74/209 (35%), Gaps = 10/209 (4%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 + RL NG+V+ + + A S L + GS + G +H L ++ + K + Sbjct: 4 EFTRLPNGLVIASLENY-APASRIGLFIKAGSRYENSNNLGTSHLL-RLASSLTTKGASS 61 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 + ++ GG + ++ A+ +E D + ++ L + P + Sbjct: 62 FKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVA---- 117 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKP-GNPVQQALKDFHE 223 A+ +L + + + N + + N D G L D+ + Sbjct: 118 ALQPQLRIDKAVA--LQNPQAHVIENLHAAAYRNALANSLYCPDYRIGKVTPVELHDYVQ 175 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTF 252 ++++ M + P L ++A Sbjct: 176 NHFTSARMALIGLG-VSHPVLKQVAEQFL 203 >2BCC-B nrPDB Length = 422 Score = 68.6 bits (166), Expect = 1e-11, Method: Composition-based stats. Identities = 30/209 (14%), Positives = 70/209 (33%), Gaps = 10/209 (4%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 + +L NG+V+ + + S + + GS + + G +H L ++ + K + Sbjct: 8 EITKLPNGLVIASLENYSP-GSTIGVFIKAGSRYENSSNLGTSHLL-RLASSLTTKGASS 65 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 + ++ GG + + A+ +E D + ++ L + P R Sbjct: 66 FKITRGIEAVGGKLSVESTRENMAYTVECLRDDVEILMEFLLNVTTAPEF------RPWE 119 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKP-GNPVQQALKDFHE 223 + + + + + N + + + D G L DF + Sbjct: 120 VADLQPQLKIDKAVAFQNPQTHVIENLHAAAYRNALADSLYCPDYRIGKVTSVELHDFVQ 179 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTF 252 ++++ M V P L +A Sbjct: 180 NHFTSARMALVGLG-VSHPVLKNVAEQLL 207 >5XTH-AK nrPDB Length = 419 Score = 64.0 bits (154), Expect = 3e-10, Method: Composition-based stats. Identities = 29/209 (13%), Positives = 70/209 (33%), Gaps = 10/209 (4%) Query: 45 QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQA 104 + +L NG+V+ + + V + L + GS + + G H L ++ + K + Sbjct: 5 EFTKLPNGLVIASLENYSPVSRI-GLFIKAGSRYEDFSNLGTTHLL-RLTSSLTTKGASS 62 Query: 105 DSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERN 164 + ++ GG + + A+ +E + ++ L + P R Sbjct: 63 FKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEF------RRWE 116 Query: 165 AVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKP-GNPVQQALKDFHE 223 + + + + + N + + N D G + L F + Sbjct: 117 VADLQPQLKIDKAVAFQNPQTHVIENLHAAAYRNALANPLYCPDYRIGKVTSEELHYFVQ 176 Query: 224 KYYSANLMKAVIYSNKPLPELAKMAADTF 252 ++++ M + P L ++A Sbjct: 177 NHFTSARMALIGLG-VSHPVLKQVAEQFL 204 >3CX5-B nrPDB Length = 352 Score = 61.7 bits (148), Expect = 2e-09, Method: Composition-based stats. Identities = 50/326 (15%), Positives = 99/326 (30%), Gaps = 19/326 (5%) Query: 53 MVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYPQADSLAEYLK 112 + V P + +L+ + V GS + G+AH L + + A L + Sbjct: 1 LTVSARDAPTKISTLA-VKVHGGSRYATKD--GVAHLLNRFNFQNTNTRS-ALKLVRESE 56 Query: 113 MHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNAELTM 172 + GG+ ++ D LP V+ LAD + + V Sbjct: 57 LLGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTES---VLPAARY 113 Query: 173 ARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMK 232 + + + + A K G L L D Q +KDF +K Y+ ++ Sbjct: 114 DYAVAEQCPVKSAEDQL-YAITFRKGLGNPL--LYDGVERVSLQDIKDFADKVYTKENLE 170 Query: 233 AVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRV 292 + + +P +S + P ++ + ++ + V Sbjct: 171 VSGENVVEADLKRFVDESLLSTLPAGKSLV-SKSEPKFFLGEENRVRFIGDSVAAIGIPV 229 Query: 293 EFRIDNNSA---KFRSKTDELITYLI-----GNRSPGTLSDWLQKQGLVEGISANSDPIV 344 + + ++ LI + G L + +S+N IV Sbjct: 230 NKASLAQYEVLANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIV 289 Query: 345 NGNSGVLAISASLTDKGLANRDQVVA 370 +S ++ L N Q + Sbjct: 290 ADLKKGKDLSPAINYTKLKNAVQNES 315 >6F73-A nrPDB Length = 574 Score = 36.3 bits (82), Expect = 0.067, Method: Composition-based stats. Identities = 44/230 (19%), Positives = 68/230 (29%), Gaps = 37/230 (16%) Query: 189 INPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMA 248 N H S G + +K++ YY K E MA Sbjct: 153 KNTGHDYLGKSTGKGALSLWMHNLKSTKFIKNYKAPYYKGPAAKLGA--GVEGFEAYAMA 210 Query: 249 ADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNS---AKFRS 305 T R+ I I+ VL E + A Sbjct: 211 NSTGHRIVGGTCPTVGIVGGYTQGGGHSILSSSYGVAADNVLEWEVVTADGRHLVATPTR 270 Query: 306 KTDELITYLIGNRSPG-----TLSDWLQKQGLVEG------------------ISANS-- 340 +D L L G +++ L + G+V G ++A Sbjct: 271 NSD-LYWALSGGGGGTFAVVLSMTARLHRDGIVGGTLLGFNDSAVGNEVYWEAVAAFHAL 329 Query: 341 --DPIVNGNSGVLAI-SASLTDKG---LANRDQVVAAIFSYLNLLREKGI 384 D + GNS ++ + SLT G A+RD V + +L+ L +GI Sbjct: 330 LPDFLDGGNSFTYSVGNNSLTAYGTMPGADRDAVDRLLRPFLDDLASRGI 379 >3RPN-A nrPDB Length = 234 Score = 36.3 bits (82), Expect = 0.076, Method: Composition-based stats. Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 23/114 (20%) Query: 731 WCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQ 790 W RN+D+ + EKAG S + A LL +I P NQ Sbjct: 126 WSRNEDITEPQSILAAAEKAGMSAEQA------------------QGLLEKIATPKVKNQ 167 Query: 791 LR--TEEQLGYAVFAFPMSVGRQWGMGFLLQSNDKQ---PSFLWERYKAFFPTA 839 L+ TE Y F P++V G +L +D+ L E++ P A Sbjct: 168 LKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPA 221 >3JCM-G nrPDB Length = 899 Score = 35.5 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 45/252 (17%), Positives = 80/252 (31%), Gaps = 40/252 (15%) Query: 161 RERNAVNAELTMARTRDGMRMAQVSAET-INPAHPGSKFSGGNLETLSDKPGNPVQQALK 219 R + + + + V+ NP P F +LE+ + V++AL+ Sbjct: 273 RSSDIWLENIRLHESDVHYCKTLVATAINFNPTSPLLWFKAIDLESTTVNKYRVVRKALQ 332 Query: 220 DFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIII 279 + L K + ++ KM +P T K + Sbjct: 333 EIPRD---EGLWKLAVSFEADKAQVIKMLEKATQFIPQSMDLLTAYTNLQSYHNAKMTLN 389 Query: 280 HYVPALPRKV-LRVEFRIDNNSAKFRSKTDELITYLIG-------NRSPGTLSDWLQKQG 331 + LP++ + + + D+L++ L N TLS WL++ Sbjct: 390 SFRKILPQEPEIWIISTLLEERNNPDIPVDKLVSLLKEGLLELSKNGYKATLSAWLKRAE 449 Query: 332 LVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDE 391 +L D +N A +++ L LRE G +Y E Sbjct: 450 ------------------------ALNDAPNSNL-TCQAIVYAILEWLRESG---EYESE 481 Query: 392 LANVLDIDFRYP 403 L NV I + P Sbjct: 482 LNNVDQILEKMP 493 >5OVN-B nrPDB Length = 428 Score = 35.1 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 20/108 (18%) Query: 323 LSDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREK 382 + + L+++G V+ DP N+ V AI K R + F LN L EK Sbjct: 36 IVERLEREGKVKRA----DPNNPWNTPVFAIKK----KSGKWRMLID---FRELNKLTEK 84 Query: 383 GIDKQY---------FDELANVLDIDFRYPSITRDMDYVEWLADTMIR 421 G + Q + VLDI Y +I D DY + A T+ R Sbjct: 85 GAEVQLGLPHPAGLQIKKQVTVLDIGDAYFTIPLDPDYAPYTAFTLPR 132 >5OVN-A nrPDB Length = 532 Score = 35.1 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 20/108 (18%) Query: 323 LSDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREK 382 + + L+++G V+ DP N+ V AI K R + F LN L EK Sbjct: 18 IVERLEREGKVKRA----DPNNPWNTPVFAIKK----KSGKWRMLID---FRELNKLTEK 66 Query: 383 GIDKQY---------FDELANVLDIDFRYPSITRDMDYVEWLADTMIR 421 G + Q + VLDI Y +I D DY + A T+ R Sbjct: 67 GAEVQLGLPHPAGLQIKKQVTVLDIGDAYFTIPLDPDYAPYTAFTLPR 114 >2QUB-A nrPDB Length = 615 Score = 34.3 bits (77), Expect = 0.25, Method: Composition-based stats. Identities = 38/122 (31%), Positives = 55/122 (45%), Gaps = 15/122 (12%) Query: 709 TEAQATTLAR-DVQKQLGADGSEWCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGY 767 T AQA L + D + L A G + R ++S+I + G+ + LA F P GY Sbjct: 119 TTAQAEVLGKYDSEGNLTAIGISF-RGTS---GPRESLIGDTIGDVINDLLAG-FGPKGY 173 Query: 768 -DEYTSSAYSSLLGQIVQPWFYNQLRTEEQL-------GYAVFAFPMSVGRQWGMGFLLQ 819 D YT A+ +LLG + + + L E+ + G AV + WG GF Q Sbjct: 174 ADGYTLKAFGNLLGDVAKFAQAHGLSGEDVVVSGHSLGGLAVNSMAAQSDANWG-GFYAQ 232 Query: 820 SN 821 SN Sbjct: 233 SN 234 >3SC7-X nrPDB Length = 516 Score = 34.0 bits (76), Expect = 0.36, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 56/151 (37%), Gaps = 17/151 (11%) Query: 46 AIRLDNG------MVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLM--G 97 + LDNG + + V + ++A++ GS ++G+ + +SL G Sbjct: 288 TMWLDNGRDFDGALSWVNVPASDGRRIIAAVMNSYGSNPPTTTWKGMLSFPRTLSLKKVG 347 Query: 98 SKKYPQADSLAE---YLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLL 154 ++++ + E N + P +T + AL V DA + L Sbjct: 348 TQQHFVQQPITELDTISTSLQILANQTITPGQT-LLSSIRGTALDVRVAFYPDAGSVLSL 406 Query: 155 DKKYAERERNAV-----NAELTMARTRDGMR 180 + E+ + +A L++ RT G Sbjct: 407 AVRKGASEQTVIKYTQSDATLSVDRTESGDI 437 >2YL2-A nrPDB Length = 540 Score = 33.6 bits (75), Expect = 0.43, Method: Composition-based stats. Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 16/139 (11%) Query: 520 YDHPELIVDESN---LRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQVMFALNDYLA 576 Y + ELI+D + ++ V+A + + PK L+L+N A +Q M+AL D +A Sbjct: 110 YANVELILDIAKRIPVQAVWAGWGHASENPKLP-ELLLKNGIAFMGPPSQAMWALGDKIA 168 Query: 577 GLALDQLSNQASVGGISFSTNANNGLMVN--ANGYTQRLPQLFQALLE-GYFSYTATEDQ 633 S A GI + +GL V+ N +++R+ + Q L E GY +D Sbjct: 169 S------SIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVK--DVDDG 220 Query: 634 LEQAKS-WYNQMMDSAEKG 651 L+ A+ Y M+ ++E G Sbjct: 221 LQAAEEVGYPVMIKASEGG 239 >4K3C-A nrPDB Length = 532 Score = 32.8 bits (73), Expect = 0.82, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 10/78 (12%) Query: 458 YISPKEPHN-KTAYFVDAPY---------QVDKISAQTFADWQKKAADIALSLPELNPYI 507 +IS K HN +T+ FVDA + D + F D+++ A ++L +P Sbjct: 444 FISDKYQHNVRTSVFVDAATVWNTKWKQSKADYPNLPDFGDYKRVRASAGIALQWQSPIG 503 Query: 508 PDDFSLIKSEKKYDHPEL 525 P FS K KKY E+ Sbjct: 504 PLSFSYAKPIKKYAGDEI 521 >1Q90-A nrPDB Length = 292 Score = 32.4 bits (72), Expect = 0.91, Method: Composition-based stats. Identities = 20/146 (13%), Positives = 49/146 (33%), Gaps = 18/146 (12%) Query: 131 LEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETIN 190 + +P AV L D + E +++ Y ++ + + + + M + E Sbjct: 28 QKAVEIEVPQAV--LPDTVFEAVIELPYDKQVKQVL---ANGKKGDLNVGMVLILPEGFE 82 Query: 191 PAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAAD 250 A P D+ +++ + + + + YS ++ P + ++M Sbjct: 83 LAPP-------------DRVPAEIKEKVGNLYYQPYSPEQKNILVVGPVPGKKYSEMVVP 129 Query: 251 TFGRVPNKESKKPEITVPVVTDAQKG 276 P K + P+ +G Sbjct: 130 ILSPDPAKNKNVSYLKYPIYFGGNRG 155 >1E2W-A nrPDB Length = 251 Score = 32.4 bits (72), Expect = 0.91, Method: Composition-based stats. Identities = 20/146 (13%), Positives = 49/146 (33%), Gaps = 18/146 (12%) Query: 131 LEVENDALPGAVDRLADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETIN 190 + +P AV L D + E +++ Y ++ + + + + M + E Sbjct: 28 QKAVEIEVPQAV--LPDTVFEAVIELPYDKQVKQVL---ANGKKGDLNVGMVLILPEGFE 82 Query: 191 PAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAAD 250 A P D+ +++ + + + + YS ++ P + ++M Sbjct: 83 LAPP-------------DRVPAEIKEKVGNLYYQPYSPEQKNILVVGPVPGKKYSEMVVP 129 Query: 251 TFGRVPNKESKKPEITVPVVTDAQKG 276 P K + P+ +G Sbjct: 130 ILSPDPAKNKNVSYLKYPIYFGGNRG 155 >6N9G-C nrPDB Length = 353 Score = 31.7 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 2/59 (3%) Query: 734 NKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLR 792 +++V + K+S+IF +S D +L+ + GY++YT + + L G V F ++ R Sbjct: 271 DREVAIYSKESIIF--GASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENR 327 >5XJM-A nrPDB Length = 422 Score = 31.7 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 12/86 (13%) Query: 739 VDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFY-NQLRTEEQL 797 VD+ QSVI+ + A+ VP + + SSL P FY +RT E L Sbjct: 107 VDRYQSVIYPFLSQRRNPWQASYIVPL---VWCMACLSSL------PTFYFRDVRTIEYL 157 Query: 798 GY--AVFAFPMSVGRQWGMGFLLQSN 821 G + AFP QW G L N Sbjct: 158 GVNACIMAFPPEKYAQWSAGIALMKN 183 >5UNF-A nrPDB Length = 411 Score = 31.7 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 12/86 (13%) Query: 739 VDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFY-NQLRTEEQL 797 VD+ QSVI+ + A+ VP + + SSL P FY +RT E L Sbjct: 216 VDRYQSVIYPFLSQRRNPWQASYIVPL---VWCMACLSSL------PTFYFRDVRTIEYL 266 Query: 798 GY--AVFAFPMSVGRQWGMGFLLQSN 821 G + AFP QW G L N Sbjct: 267 GVNACIMAFPPEKYAQWSAGIALMKN 292 >5MRE-88 nrPDB Length = 457 Score = 31.7 bits (70), Expect = 1.8, Method: Composition-based stats. Identities = 43/269 (15%), Positives = 90/269 (33%), Gaps = 28/269 (10%) Query: 101 YPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRL-ADAIAEPLLDKKYA 159 Y +++L K G ++A++ + N+++ V L D + + +K Sbjct: 190 YVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVFKYSNEKLNV 249 Query: 160 ------ERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNP 213 + + + R +G + A +K + +L Sbjct: 250 IEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFA-----QEIKTKLLTKSPSSLQ-IALRL 303 Query: 214 VQQALKDFHEK-----YYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVP 268 VQ+ +D E Y+A M N+ A + + P Sbjct: 304 VQENSRDHIESAIKRDLYTAANMCM----NQDSLVEFSEATKH-KLIDKQRVPYPWTKKE 358 Query: 269 VVTDAQKGIIIHYVPALPRKVLR----VEFRIDNNSAKFRSKTDELITYLIGNRSPGTLS 324 + +Q I P+LP +LR V + +K++ T++ I I R+ Sbjct: 359 QLFVSQLTSITSPKPSLPMSLLRNTSNVTWTQYPYHSKYQLPTEQEIAAYIEKRTNDDTG 418 Query: 325 DWLQKQGLVEGISANSDPIVNGNSGVLAI 353 + ++ ++ AN P G G+ ++ Sbjct: 419 AKVTEREVLNHF-ANVIPSRRGKLGIQSL 446 >1FNN-A nrPDB Length = 389 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 12/20 (60%), Positives = 16/20 (80%) Query: 365 RDQVVAAIFSYLNLLREKGI 384 R +V + ++SYLN LREKGI Sbjct: 328 RPRVHSQLWSYLNDLREKGI 347 >2FYO-A nrPDB Length = 653 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 27/197 (13%), Positives = 55/197 (27%), Gaps = 13/197 (6%) Query: 127 TAFYLEVE-NDALPGAVDRLADAI--AEPLLDKKYAERERNAVNAELTMARTRDGMRMAQ 183 T Y + +P D + + +PLLD R T + Sbjct: 37 TMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFETGV--GKELHAHL 94 Query: 184 VSAETINPAH-----PGSKFSGGNLETLS--DKPGNPVQQALK-DFHEKYYSANLMKAVI 235 ++ + N P +++ P K +++++ A + Sbjct: 95 LAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSA 154 Query: 236 YSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRVEFR 295 + + + F P+K + Y+ + FR Sbjct: 155 VRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFR 214 Query: 296 IDNNSAKFRSKTDELIT 312 + N++ R DEL T Sbjct: 215 LFNSTRIPRPNRDELFT 231 >2GQQ-A nrPDB Length = 163 Score = 30.9 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 45/98 (45%), Gaps = 9/98 (9%) Query: 326 WLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGID 385 L++QG ++G +A +P S ++ + +L +Q A+ L ++E + Sbjct: 50 RLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAV-QKLEEIQECHLV 108 Query: 386 KQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVP 423 FD L + R P ++ Y + L +T++R+P Sbjct: 109 SGDFDYL-----LKTRVPDMSA---YRKLLGETLLRLP 138 >2K7H-A nrPDB Length = 157 Score = 30.5 bits (67), Expect = 4.1, Method: Composition-based stats. Identities = 19/130 (14%), Positives = 40/130 (30%), Gaps = 10/130 (7%) Query: 231 MKAVIYSNKPLPELAKMAADTFGRVPNKES---KKPEITVPVVTDAQKGIIIHYVPALPR 287 + A D+F V N E + + D + ++H + ++ Sbjct: 16 ATLYKALVTDADNVIPKALDSFKSVENVEGNGGPGTIKKITFLEDGETKFVLHKIESIDE 75 Query: 288 KVLRVEFRIDNNSAKF----RSKTDELITYLIGNRSPGTLSDWLQKQGLVEGISANSDPI 343 L + + +A + D + S G L+ + +G N D + Sbjct: 76 ANLGYSYSVVGGAALPDTAEKITFDSKLVAGPNGGSAGKLTVKYETKG---DAEPNQDEL 132 Query: 344 VNGNSGVLAI 353 G + A+ Sbjct: 133 KTGKAKADAL 142 >6FSZ-KK nrPDB Length = 733 Score = 30.1 bits (66), Expect = 5.1, Method: Composition-based stats. Identities = 22/167 (13%), Positives = 45/167 (26%), Gaps = 32/167 (19%) Query: 158 YAERERNAVNAELTMART-----RDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGN 212 ER + EL R D + + + + + +L++ Sbjct: 433 NIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTE 492 Query: 213 PVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNK-ESKKPEITVPVVT 271 V+Q K LA + D + N E P + Sbjct: 493 HVRQ-------------NAKL----------LANLIRDALRNIKNTNEEATPIPSSETKA 529 Query: 272 DA---QKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLI 315 D + + + R + I + AK + + L+ ++ Sbjct: 530 DGILLETISVPQIRDVMERFSVLCNSNISKSRAKPVTNSSILLGKIL 576 >5K36-J nrPDB Length = 559 Score = 30.1 bits (66), Expect = 5.1, Method: Composition-based stats. Identities = 22/167 (13%), Positives = 45/167 (26%), Gaps = 32/167 (19%) Query: 158 YAERERNAVNAELTMART-----RDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGN 212 ER + EL R D + + + + + +L++ Sbjct: 308 NIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTE 367 Query: 213 PVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNK-ESKKPEITVPVVT 271 V+Q K LA + D + N E P + Sbjct: 368 HVRQ-------------NAKL----------LANLIRDALRNIKNTNEEATPIPSSETKA 404 Query: 272 DA---QKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLI 315 D + + + R + I + AK + + L+ ++ Sbjct: 405 DGILLETISVPQIRDVMERFSVLCNSNISKSRAKPVTNSSILLGKIL 451 >3UEK-A nrPDB Length = 588 Score = 29.7 bits (65), Expect = 6.2, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 25/68 (36%) Query: 237 SNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRVEFRI 296 S+K + D F R+P E K+ E A++ I + P LP + I Sbjct: 11 SSKQHGKRDSKITDHFVRIPKSEDKRKEQCEVRHQRAERKIPKYVPPNLPPDKKWLGTPI 70 Query: 297 DNNSAKFR 304 + R Sbjct: 71 EEMRKMPR 78 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.127 0.343 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,846,861 Number of Sequences: 36641 Number of extensions: 1360347 Number of successful extensions: 4120 Number of sequences better than 10.0: 45 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 4016 Number of HSP's gapped (non-prelim): 87 length of query: 962 length of database: 10,336,785 effective HSP length: 106 effective length of query: 856 effective length of database: 6,452,839 effective search space: 5523630184 effective search space used: 5523630184 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 64 (29.3 bits)