BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05452 (202 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1HTN-A nrPDB 376 e-105 1HUP-A nrPDB 69 9e-13 1KZC-1 nrPDB 66 1e-11 1KX0-A nrPDB 62 2e-10 1BUU-A nrPDB 61 3e-10 1AFA-1 nrPDB 60 6e-10 1MSB-A nrPDB 57 8e-09 2GO0-A nrPDB 50 9e-07 1LIT-A nrPDB 46 1e-05 1J34-B nrPDB 45 2e-05 3UBU-B nrPDB 45 3e-05 1V7P-A nrPDB 45 3e-05 1Y17-A nrPDB 44 5e-05 1WT9-A nrPDB 43 8e-05 1UKM-B nrPDB 43 8e-05 6NDD-A nrPDB 43 1e-04 6NDH-B nrPDB 42 2e-04 1UMR-C nrPDB 40 5e-04 1IXX-A nrPDB 40 8e-04 2KV3-A nrPDB 40 0.001 1X2W-A nrPDB 40 0.001 5F2Q-A nrPDB 39 0.001 1JZN-A nrPDB 39 0.002 2VRP-B nrPDB 38 0.002 1OZ7-A nrPDB 38 0.003 1HQ8-A nrPDB 36 0.013 1WT9-B nrPDB 34 0.047 1OZ7-B nrPDB 34 0.054 3BX4-A nrPDB 33 0.082 1UEX-A nrPDB 32 0.13 4UWW-A nrPDB 32 0.15 1V4L-B nrPDB 31 0.32 2E3X-B nrPDB 31 0.40 1C3A-B nrPDB 30 0.55 4S0U-A nrPDB 30 0.81 3GPR-B nrPDB 30 0.95 1V4L-A nrPDB 29 1.1 1H8U-A nrPDB 29 1.3 3P4X-A nrPDB 28 1.8 5MRF-Q nrPDB 28 1.9 5GOQ-A nrPDB 28 3.7 2IHF-A nrPDB 27 4.8 2IHE-A nrPDB 27 5.7 2CWA-A nrPDB 27 6.9 1GZ2-A nrPDB 26 9.8 >1HTN-A nrPDB Length = 182 Score = 376 bits (965), Expect = e-105, Method: Compositional matrix adjust. Identities = 179/181 (98%), Positives = 180/181 (99%) Query: 22 EPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKC 81 EPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTL+QEVALLKEQQALQTVCLKGTKVHMKC Sbjct: 2 EPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLSQEVALLKEQQALQTVCLKGTKVHMKC 61 Query: 82 FLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAE 141 FLAFTQTKTFHEASEDCISRGGTL TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAE Sbjct: 62 FLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAE 121 Query: 142 GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI 201 GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI Sbjct: 122 GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI 181 Query: 202 V 202 V Sbjct: 182 V 182 >1HUP-A nrPDB Length = 141 Score = 69.3 bits (168), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 45/149 (30%), Positives = 72/149 (48%), Gaps = 21/149 (14%) Query: 63 EQQALQTVCLK---------GTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSE 113 E++ALQT + G +V K FL + TF + C+ ++ TP+ +E Sbjct: 4 ERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAE 63 Query: 114 NDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQP-DGGKTEN 172 N A+ +++ E +LG+ D EG +VD+TG R+ Y NW +P + G E+ Sbjct: 64 NGAIQNLIKE------EAFLGITDEKTEGQFVDLTGNRLTYTNWN---EGEPNNAGSDED 114 Query: 173 CAVLSGAANGKWFDKRCRDQLPYICQFGI 201 C +L NG+W D C +C+F I Sbjct: 115 CVLL--LKNGQWNDVPCSTSHLAVCEFPI 141 >1KZC-1 nrPDB Length = 115 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 12/125 (9%) Query: 76 KVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGL 135 V K F++ + + A C GT+ TP+ EN A+ Q+V + +LG+ Sbjct: 1 NVGKKYFMSSVRRMPLNRAKALCSELQGTVATPRNAEENRAI-----QNVAKDV-AFLGI 54 Query: 136 NDMAAEGTWVDMTGARIAYKNWETEITAQPDG-GKTENCAVLSGAANGKWFDKRCRDQLP 194 D E + D+TG R+ Y NW +P+ G ENC VL NGKW D C D Sbjct: 55 TDQRTENVFEDLTGNRVRYTNWN---EGEPNNVGSGENCVVL--LTNGKWNDVPCSDSFL 109 Query: 195 YICQF 199 +C+F Sbjct: 110 VVCEF 114 >1KX0-A nrPDB Length = 149 Score = 61.6 bits (148), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 16/154 (10%) Query: 47 LKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLG 106 +++ ++TL ++ L + A G K K F+ + F + C GT+ Sbjct: 9 MEAEINTLKSKLELTNKLHAFSM----GKKSGKKFFVTNHERMPFSKVKALCSELRGTVA 64 Query: 107 TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQP- 165 P+ EN A+ E + S +LG+ D EG ++ +TG R+ Y NW+ + +P Sbjct: 65 IPRNAEENKAIQEVAKTSA------FLGITDEVTEGQFMYVTGGRLTYSNWKKD---EPN 115 Query: 166 DGGKTENCAVLSGAANGKWFDKRCRDQLPYICQF 199 D G E+C + NG W D C+ +C+F Sbjct: 116 DVGSGEDCVTI--VDNGLWNDVSCQASHTAVCEF 147 >1BUU-A nrPDB Length = 168 Score = 61.2 bits (147), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 16/154 (10%) Query: 47 LKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLG 106 +++ ++TL ++ L + A G K K F+ + F + C GT+ Sbjct: 28 MEAEINTLKSKLELTNKLHAFSM----GKKSGKKFFVTNHERMPFSKVKALCSELRGTVA 83 Query: 107 TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQP- 165 P+ EN A+ E + S +LG+ D EG ++ +TG R+ Y NW+ + +P Sbjct: 84 IPRNAEENKAIQEVAKTSA------FLGITDEVTEGQFMYVTGGRLTYSNWKKD---EPN 134 Query: 166 DGGKTENCAVLSGAANGKWFDKRCRDQLPYICQF 199 D G E+C + NG W D C+ +C+F Sbjct: 135 DHGSGEDCVTI--VDNGLWNDISCQASHTAVCEF 166 >1AFA-1 nrPDB Length = 154 Score = 60.1 bits (144), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 21/159 (13%) Query: 47 LKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLG 106 +++ ++TL ++ L + A G K K F+ + F + C GT+ Sbjct: 9 MEAEINTLKSKLELTNKLHAFSM----GKKSGKKFFVTNHERMPFSKVKALCSELRGTVA 64 Query: 107 TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPD 166 P+ EN A+ E + S +LG+ D EG ++ +TG R+ Y NW+ + QPD Sbjct: 65 IPRNAEENKAIQEVAKTSA------FLGITDEVTEGQFMYVTGGRLTYSNWKKD---QPD 115 Query: 167 G------GKTENCAVLSGAANGKWFDKRCRDQLPYICQF 199 G E+C + NG W D C+ +C+F Sbjct: 116 DWYGHGLGGGEDCVTI--VDNGLWNDISCQASHTAVCEF 152 >1MSB-A nrPDB Length = 115 Score = 56.6 bits (135), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 35/121 (28%), Positives = 56/121 (46%), Gaps = 12/121 (9%) Query: 80 KCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMA 139 K F+ + F + C GT+ P+ EN A+ E + S +LG+ D Sbjct: 4 KFFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQEVAKTSA------FLGITDEV 57 Query: 140 AEGTWVDMTGARIAYKNWETEITAQP-DGGKTENCAVLSGAANGKWFDKRCRDQLPYICQ 198 EG ++ +TG R+ Y NW+ + +P D G E+C + NG W D C+ +C+ Sbjct: 58 TEGQFMYVTGGRLTYSNWKKD---EPNDHGSGEDCVTI--VDNGLWNDISCQASHTAVCE 112 Query: 199 F 199 F Sbjct: 113 F 113 >2GO0-A nrPDB Length = 137 Score = 49.7 bits (117), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 42/139 (30%), Positives = 67/139 (48%), Gaps = 15/139 (10%) Query: 71 CLKGTKVH-MKCFLAFTQTKTFHEASEDCISR-GGTLGTPQTGSENDALYEYLRQSVGNE 128 C KG+K + C+ F K++ +A C R G L + +G+E + L +S+GN Sbjct: 2 CPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSGNLVSVLSGAEG-SFVSSLVKSIGNS 60 Query: 129 -AEIWLGLNDMAAEGT------WVDMTGARIAYKNWETEITAQPDGGKTENCAVLS-GAA 180 + +W+GL+D +GT W + + Y WE + G +CA LS A Sbjct: 61 YSYVWIGLHD-PTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPG---HCASLSRSTA 116 Query: 181 NGKWFDKRCRDQLPYICQF 199 +W D C +LPY+C+F Sbjct: 117 FLRWKDYNCNVRLPYVCKF 135 >1LIT-A nrPDB Length = 144 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 4/131 (3%) Query: 71 CLKGTKVHMK-CFLAFTQTKTFHEASEDCIS-RGGTLGTPQTGSENDALYEYLRQSVGNE 128 C +GT + C+ +T+ +A C + G L + T +E + +++S ++ Sbjct: 14 CPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDD 73 Query: 129 AEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKR 188 +W+GL+D W +G+ ++YK+W + + G ++ S KW D Sbjct: 74 FNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYC--VSLTSSTGFQKWKDVP 131 Query: 189 CRDQLPYICQF 199 C D+ ++C+F Sbjct: 132 CEDKFSFVCKF 142 >1J34-B nrPDB Length = 123 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 14/122 (11%) Query: 80 KCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLND 137 C+ F++ K + +A C + GG L + Q+ E D + + Q+ G+ W+GL++ Sbjct: 12 HCYKPFSEPKNWADAENFCTQQHAGGHLVSFQSSEEADFVVKLAFQTFGHSI-FWMGLSN 70 Query: 138 MAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYIC 197 + + W A + YK W E V + N KW + CR ++C Sbjct: 71 VWNQCNWQWSNAAMLRYKAWAEESYC-----------VYFKSTNNKWRSRACRMMAQFVC 119 Query: 198 QF 199 +F Sbjct: 120 EF 121 >3UBU-B nrPDB Length = 126 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/134 (23%), Positives = 63/134 (47%), Gaps = 17/134 (12%) Query: 72 LKGTKVHMKCFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGNEA 129 L+ + C+L + KT+ +A + C +GG L + + E D L +L + + + Sbjct: 6 LRWSAYEGHCYLVVKEKKTWDDAEKFCTEQRKGGHLVSVHSREEADFLV-HLAYPILDLS 64 Query: 130 EIWLGLNDM--AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 IW+GL++M + W D G ++ +K+W KT +C + + +W + Sbjct: 65 LIWMGLSNMWNDCKREWSD--GTKLDFKSW----------AKTSDCLIGKTDGDNQWLNM 112 Query: 188 RCRDQLPYICQFGI 201 C + ++C+F + Sbjct: 113 DCSKKHYFVCKFKL 126 >1V7P-A nrPDB Length = 134 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 18/136 (13%) Query: 75 TKVHMKCFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDALYEYLRQSVG-NEAEI 131 T C+LA + + ++EA C ++ G L + Q+ E + + + + + +E + Sbjct: 9 TAYDQHCYLAIGEPQNWYEAERFCTEQAKDGHLVSIQSREEGNFVAQLVSGFMHRSEIYV 68 Query: 132 WLGLNDMAAEGT----WVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAAN-GKWFD 186 W+GL D E W D G++I Y NW+ G+++ C L+ N W + Sbjct: 69 WIGLRDRREEQQCNPEWND--GSKIIYVNWKE--------GESKMCQGLTKWTNFHDWNN 118 Query: 187 KRCRDQLPYICQFGIV 202 C D P++C+F V Sbjct: 119 INCEDLYPFVCKFSAV 134 >1Y17-A nrPDB Length = 129 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 16/125 (12%) Query: 81 CFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN-EAEIWLGLND 137 C+ AF Q+KT+ +A C + GG L + ++ E D + + Q + + + +W+GL Sbjct: 13 CYKAFKQSKTWADAESFCTKQVNGGHLVSIESSGEADFVAHLIAQKIKSAKIHVWIGLRA 72 Query: 138 MAAEGT----WVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQL 193 E W D G+ I+Y+NW E + + G V KW + C + Sbjct: 73 QNKEKQCSIEWSD--GSSISYENWIEEESKKCLG-------VHKATGFRKWENFYCEQRD 123 Query: 194 PYICQ 198 P++C+ Sbjct: 124 PFVCE 128 >1WT9-A nrPDB Length = 129 Score = 43.1 bits (100), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 16/125 (12%) Query: 81 CFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN-EAEIWLGLND 137 C+ F Q+KT+ +A C + GG L + ++ E D + + + Q + + + +W+GL Sbjct: 13 CYKVFKQSKTWTDAESFCTKQVNGGHLVSIESSGEADFVGQLIAQKIKSAKIHVWIGLRA 72 Query: 138 MAAEGT----WVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQL 193 E W D G+ I+Y+NW E + + G E KW + C Q Sbjct: 73 QNKEKQCSIEWSD--GSSISYENWIEEESKKCLGVHIE-------TGFHKWENFYCEQQD 123 Query: 194 PYICQ 198 P++C+ Sbjct: 124 PFVCE 128 >1UKM-B nrPDB Length = 128 Score = 43.1 bits (100), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 14/122 (11%) Query: 81 CFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F K + EA E C+ +G L + + SE +A L +W+GLN+ Sbjct: 12 CYKVFEPVKNWTEAEEICMQQHKGSRLASIHS-SEEEAFVSKLASKALKFTSMWIGLNNP 70 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGK-WFDKRCRDQLPYIC 197 + W AR YK W+ + C V+ + WF + C + ++C Sbjct: 71 WKDCKWEWSDNARFDYKAWK----------RRPYCTVMVVKPDRIFWFTRGCEKSVSFVC 120 Query: 198 QF 199 +F Sbjct: 121 KF 122 >6NDD-A nrPDB Length = 135 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 39/140 (27%), Positives = 60/140 (42%), Gaps = 23/140 (16%) Query: 71 CLKGTKVH-MKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGN-- 127 CL G + C+ AF + KT+ EA C + GS+ +A +++ Q V N Sbjct: 4 CLPGWSAYDQHCYQAFNEPKTWDEAERFCTEQAKRGHLVSIGSDGEA--DFVAQLVTNNI 61 Query: 128 ---EAEIWLGLNDMAAE----GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLS-GA 179 E +W+GL D E W A I Y NW T G+++ C L+ Sbjct: 62 KRPELYVWIGLRDRRKEQQCSSEW--SMSASIIYVNWNT--------GESQMCQGLARWT 111 Query: 180 ANGKWFDKRCRDQLPYICQF 199 KW C+ + P++C+F Sbjct: 112 GFRKWDYSDCQAKNPFVCKF 131 >6NDH-B nrPDB Length = 124 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 14/122 (11%) Query: 81 CFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F++ KT+ +A C + +G L + + E +A L +WLGLN+ Sbjct: 12 CYRVFSELKTWEDAESFCYAQHKGSRLASIHS-REEEAFVGKLASQTLKYTSMWLGLNNP 70 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANG-KWFDKRCRDQLPYIC 197 E W A++ YK W + CAV+ + WF++ C + ++C Sbjct: 71 WKECKWEWSDDAKLDYKVWL----------RRPYCAVMVVKTDRIFWFNRGCEKTVSFVC 120 Query: 198 QF 199 +F Sbjct: 121 KF 122 >1UMR-C nrPDB Length = 125 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 14/121 (11%) Query: 81 CFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F Q T+ +A + C + G L + + E D + + QS+ + W+G N++ Sbjct: 15 CYKVFKQEMTWADAEKFCTQQHTGSHLVSFHSTEEVDFVVKMTHQSLKSTF-FWIGANNI 73 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQ 198 + W G + YK W E ++S + +W C D ++C+ Sbjct: 74 WNKCNWQWSDGTKPEYKEWHEEFE-----------CLISRTFDNQWLSAPCSDTYSFVCK 122 Query: 199 F 199 F Sbjct: 123 F 123 >1IXX-A nrPDB Length = 129 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 35/137 (25%), Positives = 64/137 (46%), Gaps = 19/137 (13%) Query: 71 CLKG-TKVHMKCFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDALYEYLRQSVGN 127 CL G + C+ AF + KT+ +A C ++G L + ++ E D + + + Q++ Sbjct: 2 CLSGWSSYEGHCYKAFEKYKTWEDAERVCTEQAKGAHLVSIESSGEADFVAQLVTQNMKR 61 Query: 128 -EAEIWLGLNDMA----AEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAAN- 181 + IW+GL W D G+ ++Y+NW I A+ ++ C L + Sbjct: 62 LDFYIWIGLRVQGKVKQCNSEWSD--GSSVSYENW---IEAE-----SKTCLGLEKETDF 111 Query: 182 GKWFDKRCRDQLPYICQ 198 KW + C Q P++C+ Sbjct: 112 RKWVNIYCGQQNPFVCE 128 >2KV3-A nrPDB Length = 131 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 10/133 (7%) Query: 71 CLKGTKVH-MKCFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGN 127 C G H C+ F + + + +A +C S G L + + E + EY+ Sbjct: 3 CAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYI-SGYQR 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANG-KWFD 186 IW+GL+D W + GA Y++W + G ++CA +S N W Sbjct: 62 SQSIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSM-----GGNKHCAEMSSNNNFLTWSS 116 Query: 187 KRCRDQLPYICQF 199 C + ++C++ Sbjct: 117 NECNKRQHFLCKY 129 >1X2W-A nrPDB Length = 129 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 18/126 (14%) Query: 81 CFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDALYEYLRQSVGN-EAEIWLGLND 137 C+ F KT+ +A C ++GG L + ++ E D + + + +++ N ++ +W+GL Sbjct: 13 CYKPFKLYKTWDDAERFCTEQAKGGHLVSIESAGEADFVAQLVTENIQNTKSYVWIGLRV 72 Query: 138 MAAE----GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAAN-GKWFDKRCRDQ 192 E W D G+ ++Y+NW I A+ ++ C L KW + C Q Sbjct: 73 QGKEKQCSSEWSD--GSSVSYENW---IEAE-----SKTCLGLEKETGFRKWVNIYCGQQ 122 Query: 193 LPYICQ 198 P++C+ Sbjct: 123 NPFVCE 128 >5F2Q-A nrPDB Length = 135 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 7/122 (5%) Query: 81 CFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F + K + +A C G L + E+ + EY+ ++E+W+GL D Sbjct: 14 CYKIFNELKAWKDAEMFCRKYKPGCHLASIHLYGESPEIAEYISDYHKGQSEVWIGLCDK 73 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAV--LSGAANGKWFDKRCRDQLPYI 196 + +W + Y +W+ QPD + + V +S W D+ C + ++ Sbjct: 74 KKDFSWEWTDRSCTDYLSWDKN---QPDHYQNKEFCVELVSNTGYRLWNDQVCESKNAFL 130 Query: 197 CQ 198 CQ Sbjct: 131 CQ 132 >1JZN-A nrPDB Length = 135 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 7/122 (5%) Query: 81 CFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F Q KT+ +A C G L + E+ + EY+ + +W+GL D Sbjct: 14 CYKIFNQLKTWEDAEMFCRKYKPGCHLASFHRYGESLEIAEYISDYHKGQENVWIGLRDK 73 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKT-ENCAVLSGAANGK-WFDKRCRDQLPYI 196 + +W + Y W+ QPD + E C L + W D+ C + ++ Sbjct: 74 KKDFSWEWTDRSCTDYLTWDKN---QPDHYQNKEFCVELVSLTGYRLWNDQVCESKDAFL 130 Query: 197 CQ 198 CQ Sbjct: 131 CQ 132 >2VRP-B nrPDB Length = 123 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/121 (21%), Positives = 51/121 (42%), Gaps = 14/121 (11%) Query: 81 CFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F + K + +A C + L + Q+ E D + + R + +W+GL+++ Sbjct: 13 CYKPFNEPKNWADAERFCKLQPKHSHLVSFQSAEEADFVVKLTRPRLKANL-VWMGLSNI 71 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQ 198 W GAR+ YK+W+ + C G + +W + C ++C+ Sbjct: 72 WHGCNWQWSDGARLNYKDWQEQ----------SECLAFRG-VHTEWLNMDCSSTCSFVCK 120 Query: 199 F 199 F Sbjct: 121 F 121 >1OZ7-A nrPDB Length = 131 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 18/128 (14%) Query: 81 CFLAFTQTKTFHEASEDCISRG--GTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C++ F + KT+ EA + C +G G L + ++ E + + +++G +IW GL++ Sbjct: 13 CYMLFKEPKTWDEAEKFCNKQGKDGHLLSIESKKEEILVDIVVSENIGKMYKIWTGLSER 72 Query: 139 AAE----GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGK-WFDKRCRDQL 193 + E W D + ++++E I + C VL + + W C + Sbjct: 73 SKEQHCSSRWSDGS----FFRSYEIAI-------RYSECFVLEKQSVFRTWVATPCENTF 121 Query: 194 PYICQFGI 201 P++C++ + Sbjct: 122 PFMCKYPV 129 >1HQ8-A nrPDB Length = 123 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 15/118 (12%) Query: 80 KCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMA 139 C+ F + KT++++ C+S+ +L + E D L L +S W+GL + Sbjct: 16 NCYQFFNEEKTWNQSQASCLSQNSSLLKIYSKEEQDFL--KLVKSYH-----WMGLVQIP 68 Query: 140 AEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYIC 197 A G+W G+ ++Y + + P G CAV ++ K + + C + YIC Sbjct: 69 ANGSWQWEDGSSLSYN--QLTLVEIPKGS----CAVY--GSSFKAYTEDCANLNTYIC 118 >1WT9-B nrPDB Length = 123 Score = 33.9 bits (76), Expect = 0.047, Method: Compositional matrix adjust. Identities = 27/122 (22%), Positives = 49/122 (40%), Gaps = 14/122 (11%) Query: 80 KCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLND 137 C+ F + K + +A C + G L + Q+ E D + + Q+ + W+GL+ Sbjct: 12 HCYKPFNEPKNWADAENFCTQQHTGSHLVSFQSTEEADFVVKLAFQTF-DYGIFWMGLSK 70 Query: 138 MAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYIC 197 + + W A + Y +W E+ V + N KW CR ++C Sbjct: 71 IWNQCNWQWSNAAMLKYTDW-----------AEESYCVYFKSTNNKWRSITCRMIANFVC 119 Query: 198 QF 199 +F Sbjct: 120 EF 121 >1OZ7-B nrPDB Length = 123 Score = 33.9 bits (76), Expect = 0.054, Method: Compositional matrix adjust. Identities = 28/131 (21%), Positives = 53/131 (40%), Gaps = 15/131 (11%) Query: 71 CLKGTKVHM-KCFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDALYEYLRQSVGN 127 CL V+ C+ F + + +A + C + G L + + E D + + N Sbjct: 2 CLPDWSVYEGYCYKVFKERMNWADAEKFCTKQHKDGHLVSFRNSKEVDFVISLAFPMLKN 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 + +W+GL D + W GA++ YK W+ E +C + N +W + Sbjct: 62 DL-VWIGLTDYWRDCNWEWSDGAQLDYKAWDNE----------RHCFIYKNTDN-QWTRR 109 Query: 188 RCRDQLPYICQ 198 C ++C+ Sbjct: 110 DCTWTFSFVCK 120 >3BX4-A nrPDB Length = 136 Score = 33.1 bits (74), Expect = 0.082, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 10/84 (11%) Query: 81 CFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQ--SVGNEAEIWLGLN 136 C+ AF + KT+ EA + C ++ G L + ++ E D + + Q + +E +W+GL Sbjct: 16 CYQAFNEQKTWDEAEKFCRAQENGAHLASIESNGEADFVSWLISQKDELADEDYVWIGLR 75 Query: 137 DMAAE----GTWVDMTGARIAYKN 156 E W D G+ ++Y+N Sbjct: 76 AQNKEQQCSSEWSD--GSSVSYEN 97 >1UEX-A nrPDB Length = 131 Score = 32.3 bits (72), Expect = 0.13, Method: Compositional matrix adjust. Identities = 27/123 (21%), Positives = 52/123 (42%), Gaps = 16/123 (13%) Query: 81 CFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEA-EIWLGLNDMA 139 C+ F + T+ +A + C+ G L + + E D + + Q++ + W+GL D + Sbjct: 15 CYKVFKKVGTWEDAEKFCVENSGHLASIDSKEEADFVTKLASQTLTKFVYDAWIGLRDES 74 Query: 140 ----AEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPY 195 W D G+ + Y+N +P T+ + W D C ++ P+ Sbjct: 75 KTQQCSPQWTD--GSSVVYEN-----VDEP----TKCFGLDVHTEYRTWTDLPCGEKNPF 123 Query: 196 ICQ 198 IC+ Sbjct: 124 ICK 126 >4UWW-A nrPDB Length = 132 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 12/123 (9%) Query: 81 CFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGNEAE--IWLGLN 136 C+ F + A C I G L + T E+ A+ +++ Q E E +W+GL Sbjct: 14 CYGYFRYELPWKRAEAWCRSIRAGAHLASIHTSEEHRAIAKFISQYHHGEEEEDVWIGLF 73 Query: 137 DMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANG-KWFDKRCRDQLPY 195 + W+D G++ Y D K ++CAVL ++ W + C ++ + Sbjct: 74 RWNSVWAWID--GSKKHYS-----ALDDDDYPKGKHCAVLDESSGFLSWDNDSCGERNAF 126 Query: 196 ICQ 198 IC+ Sbjct: 127 ICK 129 >1V4L-B nrPDB Length = 125 Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust. Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 18/123 (14%) Query: 81 CFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F Q + +A + C RG L + + E D + + ++ +W+GL+++ Sbjct: 15 CYQVFQQKMNWEDAEKFCTQQHRGSHLVSFHSSEEVDFVVSKTSPILKHDF-VWMGLSNV 73 Query: 139 AAEGT--WVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYI 196 E W D G ++ YK W + Q D + S + +W C + + Sbjct: 74 WNECAKEWSD--GTKLDYKAW----SGQSD-------CITSKTTDNQWLSMDCSSKRYVV 120 Query: 197 CQF 199 C+F Sbjct: 121 CKF 123 >2E3X-B nrPDB Length = 134 Score = 30.8 bits (68), Expect = 0.40, Method: Compositional matrix adjust. Identities = 28/128 (21%), Positives = 53/128 (41%), Gaps = 22/128 (17%) Query: 81 CFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGNE-AEIWLGL-- 135 C+ F + KT+ A C+ G L + ++ E + + + L + G W+GL Sbjct: 14 CYRVFKEHKTWEAAERFCMEHPNNGHLVSIESMEEAEFVAKLLSNTTGKFITHFWIGLMI 73 Query: 136 --NDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTE--NCAVLSGAANGK-WFDKRCR 190 + W D G+ ++Y GK E C VL + + WF++ C Sbjct: 74 KDKEQECSSEWSD--GSSVSYDKL----------GKQEFRKCFVLEKESGYRMWFNRNCE 121 Query: 191 DQLPYICQ 198 ++ ++C+ Sbjct: 122 ERYLFVCK 129 >1C3A-B nrPDB Length = 125 Score = 30.4 bits (67), Expect = 0.55, Method: Compositional matrix adjust. Identities = 28/127 (22%), Positives = 52/127 (40%), Gaps = 26/127 (20%) Query: 81 CFLAFTQTKTFHEASEDCI--SRGGTLGTPQTGSENDAL----YEYLRQSVGNEAEIWLG 134 C+ F Q + +A + C +G L + + E D + + L+ +W+G Sbjct: 15 CYQVFQQKMNWEDAEKFCTQQHKGSHLVSFHSSEEVDFVTSKTFPILKYDF-----VWIG 69 Query: 135 LNDMAAEGT--WVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQ 192 L+++ E T W D G ++ YK W GG ++S + +W C + Sbjct: 70 LSNVWNECTKEWSD--GTKLDYKAWS--------GGSD---CIVSKTTDNQWLSMDCSSK 116 Query: 193 LPYICQF 199 +C+F Sbjct: 117 YYVVCKF 123 >4S0U-A nrPDB Length = 126 Score = 29.6 bits (65), Expect = 0.81, Method: Compositional matrix adjust. Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 15/118 (12%) Query: 80 KCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMA 139 C+ F ++K ++E+ C+S+ +L + + D L L +S W+GL + Sbjct: 20 NCYQFFDESKNWYESQASCMSQNASLLKVYSKEDQDLL--KLVKSYH-----WMGLVHIP 72 Query: 140 AEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYIC 197 G+W G+ ++ N T I Q +CA+ + + G + + C YIC Sbjct: 73 TNGSWQWEDGSILS-PNLLTIIEMQKG-----DCALYASSFKG--YIENCSTPNTYIC 122 >3GPR-B nrPDB Length = 129 Score = 29.6 bits (65), Expect = 0.95, Method: Compositional matrix adjust. Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 24/129 (18%) Query: 79 MKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAE---IWLGL 135 + C+ F + KT+ EA C + GS +A + L V + + W GL Sbjct: 13 LYCYKPFKEKKTWIEAERFCAKQAENGHLVSIGSAAEADFLDLVIVVNFDKQRYRAWTGL 72 Query: 136 NDMAAEGTWVDMTGARIAYKN-WETEI----TAQPDGGKTENCAVLSGAANGKWFDKRCR 190 + + T GA ++Y+N +E I QP GK+ KW+ C Sbjct: 73 TERNLKWT----NGASVSYENLYEPYIRKCFVVQPWEGKS------------KWYKADCE 116 Query: 191 DQLPYICQF 199 ++ ++C+F Sbjct: 117 EKNAFLCKF 125 >1V4L-A nrPDB Length = 135 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/138 (18%), Positives = 59/138 (42%), Gaps = 19/138 (13%) Query: 71 CLKGTKVHMK-CFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGN 127 C+ G + + C+ AF++ K + +A C + L + ++ E D + + + + + Sbjct: 4 CIPGWSAYDRYCYQAFSEPKNWEDAESFCEEGVKTSHLVSIESSGEGDFVAQLVAEKIKT 63 Query: 128 EAE-IWLGLN----DMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLS-GAAN 181 + +W+GL + W D + + Y+N + ++ C L G Sbjct: 64 SFQYVWIGLRIQNKEQQCRSEWSDASS--VNYENLYKQ--------SSKKCYALKKGTEL 113 Query: 182 GKWFDKRCRDQLPYICQF 199 WF+ C + P++C++ Sbjct: 114 RTWFNVYCGRENPFVCKY 131 >1H8U-A nrPDB Length = 117 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 13/78 (16%) Query: 127 NEAEIWLGLNDMAAEGT-----WVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAAN 181 N+ ++W+G + G WVD G+R + W QP + +C L Sbjct: 48 NQGQVWIG-GRITGSGRCRRFQWVD--GSRWNFAYWAAH---QP-WSRGGHCVALC-TRG 99 Query: 182 GKWFDKRCRDQLPYICQF 199 G W C +LP+IC + Sbjct: 100 GYWRRAHCLRRLPFICSY 117 >3P4X-A nrPDB Length = 413 Score = 28.5 bits (62), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 17/34 (50%) Query: 99 ISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIW 132 I R G L QT E LYEYL++ N E W Sbjct: 249 IFRDGILIFAQTEEEGKELYEYLKRFKFNVGETW 282 >5MRF-Q nrPDB Length = 296 Score = 28.5 bits (62), Expect = 1.9, Method: Compositional matrix adjust. Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 168 GKTENCAVLSGAANGKWFDKRCRDQLPYICQFG 200 GKT AV + NG ++D + +PY C G Sbjct: 143 GKTRTVAVRDVSFNGSYYDADYKKVMPYRCVKG 175 >5GOQ-A nrPDB Length = 461 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 21/51 (41%) Query: 79 MKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEA 129 ++ FL T T HE DC G L E+D EYL G +A Sbjct: 72 VRNFLIETLTLQSHEKEMDCFQPGAGLMPASFKVESDGSKEYLVADFGEKA 122 >2IHF-A nrPDB Length = 239 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 14/54 (25%), Positives = 30/54 (55%), Gaps = 4/54 (7%) Query: 107 TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETE 160 T ++G E + + + + +G +AE+W D+ +G + + G R+ Y+ WE + Sbjct: 41 TDESGQEREVPWYHRVRLLGRQAEMW---GDLLEKGQLIFVEG-RLEYRQWEKD 90 >2IHE-A nrPDB Length = 264 Score = 26.9 bits (58), Expect = 5.7, Method: Compositional matrix adjust. Identities = 14/54 (25%), Positives = 30/54 (55%), Gaps = 4/54 (7%) Query: 107 TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETE 160 T ++G E + + + + +G +AE+W D+ +G + + G R+ Y+ WE + Sbjct: 41 TDESGQEREVPWYHRVRLLGRQAEMW---GDLLEKGQLIFVEG-RLEYRQWEKD 90 >2CWA-A nrPDB Length = 263 Score = 26.6 bits (57), Expect = 6.9, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%) Query: 110 TGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETE 160 G E + + + + +G +AE+W D+ +G V + G R+ Y+ WE E Sbjct: 44 NGGEREVSWYHRVRLLGRQAEMW---GDLLDQGQLVFVEG-RLEYRQWERE 90 >1GZ2-A nrPDB Length = 142 Score = 26.2 bits (56), Expect = 9.8, Method: Compositional matrix adjust. Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 5/74 (6%) Query: 126 GNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSG-AANGKW 184 G + +W+GL+ A +W G + +W A+ G CA L A W Sbjct: 70 GADGRVWIGLHRPAGSRSWRWSDGTAPRFASWHRTAKARRGG----RCAALRDEEAFTSW 125 Query: 185 FDKRCRDQLPYICQ 198 + C ++ ++C+ Sbjct: 126 AARPCTERNAFVCK 139 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1HTN-A nrPDB 265 1e-71 1BUU-A nrPDB 154 2e-38 1KX0-A nrPDB 150 4e-37 1AFA-1 nrPDB 148 2e-36 1LIT-A nrPDB 146 7e-36 6NDD-A nrPDB 138 2e-33 3UBU-B nrPDB 134 2e-32 1V7P-A nrPDB 134 3e-32 1Y17-A nrPDB 133 4e-32 1WT9-A nrPDB 133 6e-32 1X2W-A nrPDB 133 7e-32 1IXX-A nrPDB 129 8e-31 1HUP-A nrPDB 129 8e-31 1J34-B nrPDB 129 1e-30 2GO0-A nrPDB 129 1e-30 2KV3-A nrPDB 127 3e-30 5F2Q-A nrPDB 126 8e-30 1UMR-C nrPDB 126 9e-30 6NDH-B nrPDB 125 1e-29 1UKM-B nrPDB 123 4e-29 1MSB-A nrPDB 122 7e-29 1KZC-1 nrPDB 118 1e-27 Sequences not found previously or not previously below threshold: 1JZN-A nrPDB 122 1e-28 1WT9-B nrPDB 119 1e-27 1C3A-B nrPDB 118 1e-27 2VRP-B nrPDB 117 2e-27 1V4L-B nrPDB 117 4e-27 1OZ7-B nrPDB 116 5e-27 3BX4-A nrPDB 114 4e-26 3UBU-A nrPDB 112 7e-26 1UEX-A nrPDB 112 1e-25 1V4L-A nrPDB 111 2e-25 1U0N-C nrPDB 108 1e-24 1IJK-B nrPDB 106 7e-24 1UMR-A nrPDB 105 1e-23 2E3X-C nrPDB 104 2e-23 2E3X-B nrPDB 102 1e-22 1UEX-B nrPDB 99 2e-21 1OZ7-A nrPDB 94 3e-20 4UWW-A nrPDB 93 1e-19 3GPR-B nrPDB 90 5e-19 3GPR-A nrPDB 88 2e-18 1GZ2-A nrPDB 78 3e-15 1HQ8-A nrPDB 64 3e-11 4C16-A nrPDB 63 8e-11 4S0U-A nrPDB 60 8e-10 1H8U-A nrPDB 54 4e-08 5B1R-A nrPDB 36 0.011 4TKO-B nrPDB 29 1.6 6EZN-A nrPDB 29 1.9 2I94-A nrPDB 28 3.0 1GOW-A nrPDB 27 3.9 >1HTN-A nrPDB Length = 182 Score = 265 bits (677), Expect = 1e-71, Method: Composition-based stats. Identities = 179/181 (98%), Positives = 180/181 (99%) Query: 22 EPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKC 81 EPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTL+QEVALLKEQQALQTVCLKGTKVHMKC Sbjct: 2 EPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLSQEVALLKEQQALQTVCLKGTKVHMKC 61 Query: 82 FLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAE 141 FLAFTQTKTFHEASEDCISRGGTL TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAE Sbjct: 62 FLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAE 121 Query: 142 GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI 201 GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI Sbjct: 122 GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI 181 Query: 202 V 202 V Sbjct: 182 V 182 >1BUU-A nrPDB Length = 168 Score = 154 bits (390), Expect = 2e-38, Method: Composition-based stats. Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 21/181 (11%) Query: 25 TQKPKKIVNAKKDVVNTKMFE----ELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMK 80 +Q PK K D +++ E +++ ++TL ++ L + A G K K Sbjct: 5 SQGPK---GQKGDRGDSRAIEVKLANMEAEINTLKSKLELTNKLHAFSM----GKKSGKK 57 Query: 81 CFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAA 140 F+ + F + C GT+ P+ EN A+ E + S +LG+ D Sbjct: 58 FFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQEVAKTSA------FLGITDEVT 111 Query: 141 EGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFG 200 EG ++ +TG R+ Y NW+ + D G E+C + NG W D C+ +C+F Sbjct: 112 EGQFMYVTGGRLTYSNWKKDEPN--DHGSGEDCVTI--VDNGLWNDISCQASHTAVCEFP 167 Query: 201 I 201 Sbjct: 168 A 168 >1KX0-A nrPDB Length = 149 Score = 150 bits (378), Expect = 4e-37, Method: Composition-based stats. Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 14/155 (9%) Query: 47 LKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLG 106 +++ ++TL ++ L + A G K K F+ + F + C GT+ Sbjct: 9 MEAEINTLKSKLELTNKLHAFSM----GKKSGKKFFVTNHERMPFSKVKALCSELRGTVA 64 Query: 107 TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPD 166 P+ EN A+ E + S +LG+ D EG ++ +TG R+ Y NW+ + D Sbjct: 65 IPRNAEENKAIQEVAKTSA------FLGITDEVTEGQFMYVTGGRLTYSNWKKDEPN--D 116 Query: 167 GGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI 201 G E+C + NG W D C+ +C+F Sbjct: 117 VGSGEDCVTI--VDNGLWNDVSCQASHTAVCEFPA 149 >1AFA-1 nrPDB Length = 154 Score = 148 bits (373), Expect = 2e-36, Method: Composition-based stats. Identities = 40/158 (25%), Positives = 68/158 (43%), Gaps = 15/158 (9%) Query: 47 LKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLG 106 +++ ++TL ++ L + A G K K F+ + F + C GT+ Sbjct: 9 MEAEINTLKSKLELTNKLHAFSM----GKKSGKKFFVTNHERMPFSKVKALCSELRGTVA 64 Query: 107 TPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPD 166 P+ EN A+ E + S +LG+ D EG ++ +TG R+ Y NW+ + Sbjct: 65 IPRNAEENKAIQEVAKTSA------FLGITDEVTEGQFMYVTGGRLTYSNWKKDQPDDWY 118 Query: 167 G---GKTENCAVLSGAANGKWFDKRCRDQLPYICQFGI 201 G G E+C + NG W D C+ +C+F Sbjct: 119 GHGLGGGEDCVTI--VDNGLWNDISCQASHTAVCEFPA 154 >1LIT-A nrPDB Length = 144 Score = 146 bits (368), Expect = 7e-36, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 63/140 (45%), Gaps = 4/140 (2%) Query: 63 EQQALQTVCLKGTKVHMK-CFLAFTQTKTFHEASEDCIS-RGGTLGTPQTGSENDALYEY 120 E + C +GT + C+ +T+ +A C + G L + T +E + Sbjct: 6 ELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASL 65 Query: 121 LRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAA 180 +++S ++ +W+GL+D W +G+ ++YK+W + + G ++ S Sbjct: 66 IKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYC--VSLTSSTG 123 Query: 181 NGKWFDKRCRDQLPYICQFG 200 KW D C D+ ++C+F Sbjct: 124 FQKWKDVPCEDKFSFVCKFK 143 >6NDD-A nrPDB Length = 135 Score = 138 bits (347), Expect = 2e-33, Method: Composition-based stats. Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 15/137 (10%) Query: 71 CLKGTKVH-MKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 CL G + C+ AF + KT+ EA C + G L + + E D + + + ++ Sbjct: 4 CLPGWSAYDQHCYQAFNEPKTWDEAERFCTEQAKRGHLVSIGSDGEADFVAQLVTNNIKR 63 Query: 128 -EAEIWLGLNDMAAEGTW--VDMTGARIAYKNWETEITAQPDGGKTENCAVLS-GAANGK 183 E +W+GL D E A I Y NW T G+++ C L+ K Sbjct: 64 PELYVWIGLRDRRKEQQCSSEWSMSASIIYVNWNT--------GESQMCQGLARWTGFRK 115 Query: 184 WFDKRCRDQLPYICQFG 200 W C+ + P++C+F Sbjct: 116 WDYSDCQAKNPFVCKFP 132 >3UBU-B nrPDB Length = 126 Score = 134 bits (338), Expect = 2e-32, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 61/132 (46%), Gaps = 13/132 (9%) Query: 72 LKGTKVHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGNEA 129 L+ + C+L + KT+ +A + C + GG L + + E D L +L + + + Sbjct: 6 LRWSAYEGHCYLVVKEKKTWDDAEKFCTEQRKGGHLVSVHSREEADFLV-HLAYPILDLS 64 Query: 130 EIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRC 189 IW+GL++M + G ++ +K+W KT +C + + +W + C Sbjct: 65 LIWMGLSNMWNDCKREWSDGTKLDFKSW----------AKTSDCLIGKTDGDNQWLNMDC 114 Query: 190 RDQLPYICQFGI 201 + ++C+F + Sbjct: 115 SKKHYFVCKFKL 126 >1V7P-A nrPDB Length = 134 Score = 134 bits (336), Expect = 3e-32, Method: Composition-based stats. Identities = 33/139 (23%), Positives = 60/139 (43%), Gaps = 15/139 (10%) Query: 71 CLK-GTKVHMKCFLAFTQTKTFHEASEDCISRG--GTLGTPQTGSENDALYEYLRQSVG- 126 C T C+LA + + ++EA C + G L + Q+ E + + + + + Sbjct: 4 CPSDWTAYDQHCYLAIGEPQNWYEAERFCTEQAKDGHLVSIQSREEGNFVAQLVSGFMHR 63 Query: 127 NEAEIWLGLNDMAAEGTW--VDMTGARIAYKNWETEITAQPDGGKTENCAVLS-GAANGK 183 +E +W+GL D E G++I Y NW+ G+++ C L+ Sbjct: 64 SEIYVWIGLRDRREEQQCNPEWNDGSKIIYVNWKE--------GESKMCQGLTKWTNFHD 115 Query: 184 WFDKRCRDQLPYICQFGIV 202 W + C D P++C+F V Sbjct: 116 WNNINCEDLYPFVCKFSAV 134 >1Y17-A nrPDB Length = 129 Score = 133 bits (335), Expect = 4e-32, Method: Composition-based stats. Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 12/131 (9%) Query: 73 KGTKVHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN-EA 129 + C+ AF Q+KT+ +A C + GG L + ++ E D + + Q + + + Sbjct: 5 SWSSYEGHCYKAFKQSKTWADAESFCTKQVNGGHLVSIESSGEADFVAHLIAQKIKSAKI 64 Query: 130 EIWLGLNDMAAE--GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 +W+GL E + G+ I+Y+NW E + + G V KW + Sbjct: 65 HVWIGLRAQNKEKQCSIEWSDGSSISYENWIEEESKKCLG-------VHKATGFRKWENF 117 Query: 188 RCRDQLPYICQ 198 C + P++C+ Sbjct: 118 YCEQRDPFVCE 128 >1WT9-A nrPDB Length = 129 Score = 133 bits (334), Expect = 6e-32, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 13/134 (9%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F Q+KT+ +A C + GG L + ++ E D + + + Q + + Sbjct: 2 CSSGWSSYEGHCYKVFKQSKTWTDAESFCTKQVNGGHLVSIESSGEADFVGQLIAQKIKS 61 Query: 128 -EAEIWLGLNDMAAE--GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKW 184 + +W+GL E + G+ I+Y+NW E + + G E KW Sbjct: 62 AKIHVWIGLRAQNKEKQCSIEWSDGSSISYENWIEEESKKCLGVHIE-------TGFHKW 114 Query: 185 FDKRCRDQLPYICQ 198 + C Q P++C+ Sbjct: 115 ENFYCEQQDPFVCE 128 >1X2W-A nrPDB Length = 129 Score = 133 bits (333), Expect = 7e-32, Method: Composition-based stats. Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 15/135 (11%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F KT+ +A C + GG L + ++ E D + + + +++ N Sbjct: 2 CPSGWSSYEGHCYKPFKLYKTWDDAERFCTEQAKGGHLVSIESAGEADFVAQLVTENIQN 61 Query: 128 -EAEIWLGLNDMAAE--GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSG-AANGK 183 ++ +W+GL E + G+ ++Y+NW +++ C L K Sbjct: 62 TKSYVWIGLRVQGKEKQCSSEWSDGSSVSYENWIE--------AESKTCLGLEKETGFRK 113 Query: 184 WFDKRCRDQLPYICQ 198 W + C Q P++C+ Sbjct: 114 WVNIYCGQQNPFVCE 128 >1IXX-A nrPDB Length = 129 Score = 129 bits (324), Expect = 8e-31, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 15/135 (11%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 CL G C+ AF + KT+ +A C + G L + ++ E D + + + Q++ Sbjct: 2 CLSGWSSYEGHCYKAFEKYKTWEDAERVCTEQAKGAHLVSIESSGEADFVAQLVTQNMKR 61 Query: 128 -EAEIWLGLNDMA--AEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSG-AANGK 183 + IW+GL + G+ ++Y+NW +++ C L K Sbjct: 62 LDFYIWIGLRVQGKVKQCNSEWSDGSSVSYENWIE--------AESKTCLGLEKETDFRK 113 Query: 184 WFDKRCRDQLPYICQ 198 W + C Q P++C+ Sbjct: 114 WVNIYCGQQNPFVCE 128 >1HUP-A nrPDB Length = 141 Score = 129 bits (324), Expect = 8e-31, Method: Composition-based stats. Identities = 44/149 (29%), Positives = 70/149 (46%), Gaps = 19/149 (12%) Query: 62 KEQQALQTVCLK---------GTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGS 112 E++ALQT + G +V K FL + TF + C+ ++ TP+ + Sbjct: 3 SERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAA 62 Query: 113 ENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTEN 172 EN A+ +++ E +LG+ D EG +VD+TG R+ Y NW + G E+ Sbjct: 63 ENGAIQNLIKE------EAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPN--NAGSDED 114 Query: 173 CAVLSGAANGKWFDKRCRDQLPYICQFGI 201 C +L NG+W D C +C+F I Sbjct: 115 CVLLLK--NGQWNDVPCSTSHLAVCEFPI 141 >1J34-B nrPDB Length = 123 Score = 129 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 31/134 (23%), Positives = 55/134 (41%), Gaps = 15/134 (11%) Query: 71 CLK-GTKVHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C + C+ F++ K + +A C + GG L + Q+ E D + + Q+ G+ Sbjct: 2 CPSDWSSYEGHCYKPFSEPKNWADAENFCTQQHAGGHLVSFQSSEEADFVVKLAFQTFGH 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 W+GL+++ + W A + YK W E V + N KW + Sbjct: 62 SI-FWMGLSNVWNQCNWQWSNAAMLRYKAWAEESY-----------CVYFKSTNNKWRSR 109 Query: 188 RCRDQLPYICQFGI 201 CR ++C+F Sbjct: 110 ACRMMAQFVCEFQA 123 >2GO0-A nrPDB Length = 137 Score = 129 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 11/137 (8%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR-GGTLGTPQTGSENDALYEYLRQSVGNE 128 C KG+K C+ F K++ +A C R G L + +G+E + ++ + Sbjct: 2 CPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSY 61 Query: 129 AEIWLGLNDMAAEGT-----WVDMTGARIAYKNWETEITAQPDGGKTENCAVLS-GAANG 182 + +W+GL+D W + + Y WE + G +CA LS A Sbjct: 62 SYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPG---HCASLSRSTAFL 118 Query: 183 KWFDKRCRDQLPYICQF 199 +W D C +LPY+C+F Sbjct: 119 RWKDYNCNVRLPYVCKF 135 >2KV3-A nrPDB Length = 131 Score = 127 bits (319), Expect = 3e-30, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 55/133 (41%), Gaps = 10/133 (7%) Query: 71 CLKGTKVHM-KCFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGN 127 C G H C+ F + + + +A +C S G L + + E + EY+ Sbjct: 3 CAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYI-SGYQR 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGK-WFD 186 IW+GL+D W + GA Y++W + G ++CA +S N W Sbjct: 62 SQSIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSM-----GGNKHCAEMSSNNNFLTWSS 116 Query: 187 KRCRDQLPYICQF 199 C + ++C++ Sbjct: 117 NECNKRQHFLCKY 129 >5F2Q-A nrPDB Length = 135 Score = 126 bits (315), Expect = 8e-30, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 7/122 (5%) Query: 81 CFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F + K + +A C G L + E+ + EY+ ++E+W+GL D Sbjct: 14 CYKIFNELKAWKDAEMFCRKYKPGCHLASIHLYGESPEIAEYISDYHKGQSEVWIGLCDK 73 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAV--LSGAANGKWFDKRCRDQLPYI 196 + +W + Y +W+ QPD + + V +S W D+ C + ++ Sbjct: 74 KKDFSWEWTDRSCTDYLSWDKN---QPDHYQNKEFCVELVSNTGYRLWNDQVCESKNAFL 130 Query: 197 CQ 198 CQ Sbjct: 131 CQ 132 >1UMR-C nrPDB Length = 125 Score = 126 bits (315), Expect = 9e-30, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 51/130 (39%), Gaps = 14/130 (10%) Query: 74 GTKVHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGNEAEI 131 + C+ F Q T+ +A + C + G L + + E D + + QS+ + Sbjct: 8 WSSYDRYCYKVFKQEMTWADAEKFCTQQHTGSHLVSFHSTEEVDFVVKMTHQSLKSTF-F 66 Query: 132 WLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRD 191 W+G N++ + W G + YK W E ++S + +W C D Sbjct: 67 WIGANNIWNKCNWQWSDGTKPEYKEWHEEFE-----------CLISRTFDNQWLSAPCSD 115 Query: 192 QLPYICQFGI 201 ++C+F Sbjct: 116 TYSFVCKFEA 125 >6NDH-B nrPDB Length = 124 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 57/131 (43%), Gaps = 14/131 (10%) Query: 72 LKGTKVHMKCFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGNEA 129 L + + C+ F++ KT+ +A C +G L + + E + + Q++ Sbjct: 3 LHWSSYNGYCYRVFSELKTWEDAESFCYAQHKGSRLASIHSREEEAFVGKLASQTLK-YT 61 Query: 130 EIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANG-KWFDKR 188 +WLGLN+ E W A++ YK W + CAV+ + WF++ Sbjct: 62 SMWLGLNNPWKECKWEWSDDAKLDYKVWL----------RRPYCAVMVVKTDRIFWFNRG 111 Query: 189 CRDQLPYICQF 199 C + ++C+F Sbjct: 112 CEKTVSFVCKF 122 >1UKM-B nrPDB Length = 128 Score = 123 bits (309), Expect = 4e-29, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 50/133 (37%), Gaps = 15/133 (11%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F K + EA E C +G L + + E +A L Sbjct: 1 CPLGWSSFDQHCYKVFEPVKNWTEAEEICMQQHKGSRLASIHSSEE-EAFVSKLASKALK 59 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANG-KWFD 186 +W+GLN+ + W AR YK W+ + C V+ + WF Sbjct: 60 FTSMWIGLNNPWKDCKWEWSDNARFDYKAWK----------RRPYCTVMVVKPDRIFWFT 109 Query: 187 KRCRDQLPYICQF 199 + C + ++C+F Sbjct: 110 RGCEKSVSFVCKF 122 >1MSB-A nrPDB Length = 115 Score = 122 bits (307), Expect = 7e-29, Method: Composition-based stats. Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 10/125 (8%) Query: 77 VHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLN 136 K F+ + F + C GT+ P+ EN A+ E + S +LG+ Sbjct: 1 SGKKFFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQEVAKTSA------FLGIT 54 Query: 137 DMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYI 196 D EG ++ +TG R+ Y NW+ + D G E+C + NG W D C+ + Sbjct: 55 DEVTEGQFMYVTGGRLTYSNWKKDEPN--DHGSGEDCVTI--VDNGLWNDISCQASHTAV 110 Query: 197 CQFGI 201 C+F Sbjct: 111 CEFPA 115 >1JZN-A nrPDB Length = 135 Score = 122 bits (306), Expect = 1e-28, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 7/122 (5%) Query: 81 CFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDM 138 C+ F Q KT+ +A C G L + E+ + EY+ + +W+GL D Sbjct: 14 CYKIFNQLKTWEDAEMFCRKYKPGCHLASFHRYGESLEIAEYISDYHKGQENVWIGLRDK 73 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAV--LSGAANGKWFDKRCRDQLPYI 196 + +W + Y W+ QPD + + V +S W D+ C + ++ Sbjct: 74 KKDFSWEWTDRSCTDYLTWDKN---QPDHYQNKEFCVELVSLTGYRLWNDQVCESKDAFL 130 Query: 197 CQ 198 CQ Sbjct: 131 CQ 132 >1WT9-B nrPDB Length = 123 Score = 119 bits (297), Expect = 1e-27, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 50/134 (37%), Gaps = 15/134 (11%) Query: 71 CLK-GTKVHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C + C+ F + K + +A C + G L + Q+ E D + + Q+ + Sbjct: 2 CPSDWSSYEGHCYKPFNEPKNWADAENFCTQQHTGSHLVSFQSTEEADFVVKLAFQTF-D 60 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 W+GL+ + + W A + Y +W E V + N KW Sbjct: 61 YGIFWMGLSKIWNQCNWQWSNAAMLKYTDWAEESY-----------CVYFKSTNNKWRSI 109 Query: 188 RCRDQLPYICQFGI 201 CR ++C+F Sbjct: 110 TCRMIANFVCEFQA 123 >1C3A-B nrPDB Length = 125 Score = 118 bits (296), Expect = 1e-27, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 48/134 (35%), Gaps = 15/134 (11%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F Q + +A + C + G L + + E D + + Sbjct: 4 CPLGWSSYDEHCYQVFQQKMNWEDAEKFCTQQHKGSHLVSFHSSEEVDFVTSKTF-PILK 62 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 +W+GL+++ E T G ++ YK W ++S + +W Sbjct: 63 YDFVWIGLSNVWNECTKEWSDGTKLDYKAWSGGSD-----------CIVSKTTDNQWLSM 111 Query: 188 RCRDQLPYICQFGI 201 C + +C+F Sbjct: 112 DCSSKYYVVCKFQA 125 >1KZC-1 nrPDB Length = 115 Score = 118 bits (296), Expect = 1e-27, Method: Composition-based stats. Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 10/125 (8%) Query: 76 KVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGL 135 V K F++ + + A C GT+ TP+ EN A+ + +LG+ Sbjct: 1 NVGKKYFMSSVRRMPLNRAKALCSELQGTVATPRNAEENRAIQNVAKD------VAFLGI 54 Query: 136 NDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPY 195 D E + D+TG R+ Y NW + G ENC VL NGKW D C D Sbjct: 55 TDQRTENVFEDLTGNRVRYTNWNEGEPN--NVGSGENCVVL--LTNGKWNDVPCSDSFLV 110 Query: 196 ICQFG 200 +C+F Sbjct: 111 VCEFS 115 >2VRP-B nrPDB Length = 123 Score = 117 bits (294), Expect = 2e-27, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 50/134 (37%), Gaps = 15/134 (11%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F + K + +A C + L + Q+ E D + + R + Sbjct: 2 CPSGWSSYEGHCYKPFNEPKNWADAERFCKLQPKHSHLVSFQSAEEADFVVKLTRPRLKA 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 +W+GL+++ W GAR+ YK+W+ + G W + Sbjct: 62 NL-VWMGLSNIWHGCNWQWSDGARLNYKDWQEQSECLAFRGVHTE-----------WLNM 109 Query: 188 RCRDQLPYICQFGI 201 C ++C+F Sbjct: 110 DCSSTCSFVCKFKA 123 >1V4L-B nrPDB Length = 125 Score = 117 bits (292), Expect = 4e-27, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 49/134 (36%), Gaps = 15/134 (11%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F Q + +A + C + G L + + E D + + + Sbjct: 4 CPLGWSSYDEHCYQVFQQKMNWEDAEKFCTQQHRGSHLVSFHSSEEVDFVVSKTSPILKH 63 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 + +W+GL+++ E G ++ YK W + + S + +W Sbjct: 64 DF-VWMGLSNVWNECAKEWSDGTKLDYKAWSGQSD-----------CITSKTTDNQWLSM 111 Query: 188 RCRDQLPYICQFGI 201 C + +C+F Sbjct: 112 DCSSKRYVVCKFQA 125 >1OZ7-B nrPDB Length = 123 Score = 116 bits (291), Expect = 5e-27, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 49/134 (36%), Gaps = 15/134 (11%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 CL C+ F + + +A + C + G L + + E D + + N Sbjct: 2 CLPDWSVYEGYCYKVFKERMNWADAEKFCTKQHKDGHLVSFRNSKEVDFVISLAFPMLKN 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 + +W+GL D + W GA++ YK W+ E + + +W + Sbjct: 62 DL-VWIGLTDYWRDCNWEWSDGAQLDYKAWD-----------NERHCFIYKNTDNQWTRR 109 Query: 188 RCRDQLPYICQFGI 201 C ++C+ Sbjct: 110 DCTWTFSFVCKCPA 123 >3BX4-A nrPDB Length = 136 Score = 114 bits (284), Expect = 4e-26, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 51/132 (38%), Gaps = 15/132 (11%) Query: 74 GTKVHMKCFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQS--VGNEA 129 + C+ AF + KT+ EA + C G L + ++ E D + + Q + +E Sbjct: 9 WSPYDQHCYQAFNEQKTWDEAEKFCRAQENGAHLASIESNGEADFVSWLISQKDELADED 68 Query: 130 EIWLGLNDMAAEGTW--VDMTGARIAYKNWETEITAQPDGGKTENCAVLSG-AANGKWFD 186 +W+GL E G+ ++Y+N T+ C L KW + Sbjct: 69 YVWIGLRAQNKEQQCSSEWSDGSSVSYEN--------LIDLHTKKCGALEKLTGFRKWVN 120 Query: 187 KRCRDQLPYICQ 198 C ++C+ Sbjct: 121 YYCEQMHAFVCK 132 >3UBU-A nrPDB Length = 131 Score = 112 bits (281), Expect = 7e-26, Method: Composition-based stats. Identities = 27/136 (19%), Positives = 59/136 (43%), Gaps = 15/136 (11%) Query: 71 CLKGTKVH-MKCFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGN 127 CL G + C+ F KT+ +A + C +GG L + ++ E D + + + ++ Sbjct: 4 CLPGWSAYDQSCYRVFKLLKTWDDAEKFCTERPKGGHLVSIESAGERDFVAQLVSENKQT 63 Query: 128 EAEIWLGLNDMAA--EGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSG-AANGKW 184 + +WLGL + + + G+ ++Y+N+ +++ C VL W Sbjct: 64 D-NVWLGLKIQSKGQQCSTEWTDGSSVSYENFSE--------YQSKKCFVLEKNTGFRTW 114 Query: 185 FDKRCRDQLPYICQFG 200 + C + ++C+ Sbjct: 115 LNLNCGSEYSFVCKSP 130 >1UEX-A nrPDB Length = 131 Score = 112 bits (280), Expect = 1e-25, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 52/132 (39%), Gaps = 13/132 (9%) Query: 71 CLK-GTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEA 129 CL + C+ F + T+ +A + C+ G L + + E D + + Q++ Sbjct: 4 CLPDWSSYKGHCYKVFKKVGTWEDAEKFCVENSGHLASIDSKEEADFVTKLASQTLTKFV 63 Query: 130 E-IWLGLNDMAA--EGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFD 186 W+GL D + + + G+ + Y+N + TE W D Sbjct: 64 YDAWIGLRDESKTQQCSPQWTDGSSVVYENVDEPTKCFGLDVHTE---------YRTWTD 114 Query: 187 KRCRDQLPYICQ 198 C ++ P+IC+ Sbjct: 115 LPCGEKNPFICK 126 >1V4L-A nrPDB Length = 135 Score = 111 bits (278), Expect = 2e-25, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 55/135 (40%), Gaps = 13/135 (9%) Query: 71 CLKGTKVH-MKCFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGN 127 C+ G + C+ AF++ K + +A C + L + ++ E D + + + + + Sbjct: 4 CIPGWSAYDRYCYQAFSEPKNWEDAESFCEEGVKTSHLVSIESSGEGDFVAQLVAEKIKT 63 Query: 128 EA-EIWLGLNDMAAE--GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKW 184 +W+GL E + + Y+N + + + A+ G W Sbjct: 64 SFQYVWIGLRIQNKEQQCRSEWSDASSVNYENLYKQSSKKCY-------ALKKGTELRTW 116 Query: 185 FDKRCRDQLPYICQF 199 F+ C + P++C++ Sbjct: 117 FNVYCGRENPFVCKY 131 >1U0N-C nrPDB Length = 125 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 50/134 (37%), Gaps = 13/134 (9%) Query: 71 CLK-GTKVHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C + C+ F + + +A E C + G L + Q+ E D + + + Sbjct: 2 CPPDWSSYEGHCYRFFKEWMHWDDAEEFCTEQQTGAHLVSFQSKEEADFVRSLTSEMLKG 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 + +W+GL+D+ + + G Y ++ + V S N KW+ Sbjct: 62 DV-VWIGLSDVWNKCRFEWTDGMEFDYDDYYLIAEYE---------CVASKPTNNKWWII 111 Query: 188 RCRDQLPYICQFGI 201 C ++C+F Sbjct: 112 PCTRFKNFVCEFQA 125 >1IJK-B nrPDB Length = 133 Score = 106 bits (264), Expect = 7e-24, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 53/137 (38%), Gaps = 14/137 (10%) Query: 71 CLKGTK-VHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGS-ENDALYEYLRQSVG 126 C G C+ F Q + +A C + GG L + + S E D + + + +++ Sbjct: 2 CPSGWSSYEGNCYKFFQQKMNWADAERFCSEQAKGGHLVSIKIYSKEKDFVGDLVTKNIQ 61 Query: 127 -NEAEIWLGLN--DMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGK 183 ++ W+GL + + + G+ ++Y+N + A+ Sbjct: 62 SSDLYAWIGLRVENKEKQCSSEWSDGSSVSYENVVERTVKKC-------FALEKDLGFVL 114 Query: 184 WFDKRCRDQLPYICQFG 200 W + C + P++C+ Sbjct: 115 WINLYCAQKNPFVCKSP 131 >1UMR-A nrPDB Length = 135 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 50/136 (36%), Gaps = 13/136 (9%) Query: 71 CLKGTKVH-MKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C + C+ F + + +A C + G L + ++ E D + + Q++ Sbjct: 4 CPSDWYYYDQHCYRIFNEEMNWEDAEWFCTKQAKGAHLVSIKSAKEADFVAWMVTQNIEE 63 Query: 128 EA-EIWLGLNDMAAEGTWV--DMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKW 184 + +GL E G+ ++Y N D T+ + KW Sbjct: 64 SFSHVSIGLRVQNKEKQCSTKWSDGSSVSYDN-------LLDLYITKCSLLKKETGFRKW 116 Query: 185 FDKRCRDQLPYICQFG 200 F C ++P++C+F Sbjct: 117 FVASCIGKIPFVCKFP 132 >2E3X-C nrPDB Length = 122 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 42/132 (31%), Gaps = 15/132 (11%) Query: 71 CLKGT-KVHMKCFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F K + +A + C + G L + + E + + +++ Sbjct: 3 CPSGWLSYEQHCYKGFNDLKNWTDAEKFCTEQKKGSHLVSLHSREEEKFVVNLISENL-E 61 Query: 128 EAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDK 187 W+GL +M + + YK E ++ W Sbjct: 62 YPATWIGLGNMWKDCRMEWSDRGNVKYKALAEESY-----------CLIMITHEKVWKSM 110 Query: 188 RCRDQLPYICQF 199 C P +C+F Sbjct: 111 TCNFIAPVVCKF 122 >2E3X-B nrPDB Length = 134 Score = 102 bits (254), Expect = 1e-22, Method: Composition-based stats. Identities = 23/136 (16%), Positives = 53/136 (38%), Gaps = 13/136 (9%) Query: 71 CLKGTKVHMK-CFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGN 127 C + ++ C+ F + KT+ A C+ G L + ++ E + + + L + G Sbjct: 3 CPPDSSLYRYFCYRVFKEHKTWEAAERFCMEHPNNGHLVSIESMEEAEFVAKLLSNTTGK 62 Query: 128 EA-EIWLGL--NDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKW 184 W+GL D E + G+ ++Y + + + + W Sbjct: 63 FITHFWIGLMIKDKEQECSSEWSDGSSVSYDKLGKQEFRKC-------FVLEKESGYRMW 115 Query: 185 FDKRCRDQLPYICQFG 200 F++ C ++ ++C+ Sbjct: 116 FNRNCEERYLFVCKVP 131 >1UEX-B nrPDB Length = 125 Score = 98.7 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 49/132 (37%), Gaps = 14/132 (10%) Query: 72 LKGTKVHMKCFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGNEA 129 + C+ F KT+ +A + C GG L + + E + + + + + Sbjct: 6 PDWSSYKGHCYKVFKVEKTWADAEKFCKELVNGGHLMSVNSREEGEFISKLALEKM-RIV 64 Query: 130 EIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRC 189 +W+GL+ GAR+ Y+ E ++ + + KW C Sbjct: 65 LVWIGLSHFWRICPLRWTDGARLDYRA-----------LSDEPICFVAESFHNKWIQWTC 113 Query: 190 RDQLPYICQFGI 201 + ++C++ + Sbjct: 114 NRKKSFVCKYRV 125 >1OZ7-A nrPDB Length = 131 Score = 94.5 bits (233), Expect = 3e-20, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 57/136 (41%), Gaps = 13/136 (9%) Query: 71 CLKGTKVHM-KCFLAFTQTKTFHEASEDCISRG--GTLGTPQTGSENDALYEYLRQSVGN 127 C G + C++ F + KT+ EA + C +G G L + ++ E + + +++G Sbjct: 2 CPPGWSSNGVYCYMLFKEPKTWDEAEKFCNKQGKDGHLLSIESKKEEILVDIVVSENIGK 61 Query: 128 EAEIWLGLNDMAAE--GTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWF 185 +IW GL++ + E + G+ + + +E + + W Sbjct: 62 MYKIWTGLSERSKEQHCSSRWSDGSFFR--------SYEIAIRYSECFVLEKQSVFRTWV 113 Query: 186 DKRCRDQLPYICQFGI 201 C + P++C++ + Sbjct: 114 ATPCENTFPFMCKYPV 129 >4UWW-A nrPDB Length = 132 Score = 92.6 bits (228), Expect = 1e-19, Method: Composition-based stats. Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 13/134 (9%) Query: 71 CLKGT-KVHMKCFLAFTQTKTFHEASEDC--ISRGGTLGTPQTGSENDALYEYLRQSVGN 127 C KG C+ F + A C I G L + T E+ A+ +++ Q Sbjct: 3 CPKGWLDFRGNCYGYFRYELPWKRAEAWCRSIRAGAHLASIHTSEEHRAIAKFISQYHHG 62 Query: 128 EAE--IWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVL-SGAANGKW 184 E E +W+GL W + G++ Y + + D K ++CAVL + W Sbjct: 63 EEEEDVWIGL--FRWNSVWAWIDGSKKHYSALDDD-----DYPKGKHCAVLDESSGFLSW 115 Query: 185 FDKRCRDQLPYICQ 198 + C ++ +IC+ Sbjct: 116 DNDSCGERNAFICK 129 >3GPR-B nrPDB Length = 129 Score = 90.3 bits (222), Expect = 5e-19, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 48/134 (35%), Gaps = 15/134 (11%) Query: 71 CLKGTKVHM-KCFLAFTQTKTFHEASEDCISRG--GTLGTPQTGSENDALYEYLRQSVGN 127 C C+ F + KT+ EA C + G L + + +E D L + + Sbjct: 4 CPTTWSASKLYCYKPFKEKKTWIEAERFCAKQAENGHLVSIGSAAEADFLDLVIVVNFDK 63 Query: 128 EAE-IWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFD 186 + W GL E GA ++Y+N + + V KW+ Sbjct: 64 QRYRAWTGL----TERNLKWTNGASVSYEN-------LYEPYIRKCFVVQPWEGKSKWYK 112 Query: 187 KRCRDQLPYICQFG 200 C ++ ++C+F Sbjct: 113 ADCEEKNAFLCKFP 126 >3GPR-A nrPDB Length = 133 Score = 88.3 bits (217), Expect = 2e-18, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 48/137 (35%), Gaps = 13/137 (9%) Query: 71 CLKGTKVHMK-CFLAFTQTKTFHEASEDCISR--GGTLGTPQTGSENDALYEYLRQSVGN 127 C G C+ F + KT+ EA C + L + + E + + + N Sbjct: 2 CPDGWSSTKSYCYRPFKEKKTWEEAERFCTEQEKEAHLVSMENRLEAVFVDMVMENNFEN 61 Query: 128 EAE-IWLGLN--DMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKW 184 + W+GL + G+ I+Y+N + + + KW Sbjct: 62 KIYRSWIGLKIENKGQRSNLEWSDGSSISYENLYEPYMEKC-------FLMDHQSGLPKW 114 Query: 185 FDKRCRDQLPYICQFGI 201 C ++ ++C+F + Sbjct: 115 HTADCEEKNVFMCKFQL 131 >1GZ2-A nrPDB Length = 142 Score = 77.9 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 51/139 (36%), Gaps = 15/139 (10%) Query: 71 CLKGT-KVHMKCFLAFTQTKTFHEASEDCIS--RGGTLGTPQTGSENDALYEYLRQSVGN 127 C G C F++ ++ A C G L ++ +E L E L S G Sbjct: 5 CGPGWVPTPGGCLGFFSRELSWSRAESFCRRWGPGSHLAAVRSAAELRLLAELLNASRGG 64 Query: 128 EAE-------IWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLS-GA 179 + +W+GL+ A +W G + +W A+ + CA L Sbjct: 65 DGSGEGADGRVWIGLHRPAGSRSWRWSDGTAPRFASWHRTAKAR----RGGRCAALRDEE 120 Query: 180 ANGKWFDKRCRDQLPYICQ 198 A W + C ++ ++C+ Sbjct: 121 AFTSWAARPCTERNAFVCK 139 >1HQ8-A nrPDB Length = 123 Score = 64.4 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 16/128 (12%) Query: 71 CLKGTKVHMK-CFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEA 129 C H C+ F + KT++++ C+S+ +L + E D L ++ Sbjct: 6 CPNNWICHRNNCYQFFNEEKTWNQSQASCLSQNSSLLKIYSKEEQDFLKLV-------KS 58 Query: 130 EIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRC 189 W+GL + A G+W G+ ++Y + G CAV + K + + C Sbjct: 59 YHWMGLVQIPANGSWQWEDGSSLSY---NQLTLVEIPKGS---CAVYGSS--FKAYTEDC 110 Query: 190 RDQLPYIC 197 + YIC Sbjct: 111 ANLNTYIC 118 >4C16-A nrPDB Length = 280 Score = 62.9 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 45/120 (37%), Gaps = 9/120 (7%) Query: 82 FLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAE 141 + T+ T+ EAS C R L Q E + L L S + W+G+ Sbjct: 3 YNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYS---PSYYWIGIR--KVN 57 Query: 142 GTWVDMTGARIAYKNWETEITAQPDG-GKTENCAVL---SGAANGKWFDKRCRDQLPYIC 197 WV + + + + +P+ K E+C + G W D+RC + +C Sbjct: 58 NVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALC 117 >4S0U-A nrPDB Length = 126 Score = 59.8 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 50/128 (39%), Gaps = 16/128 (12%) Query: 71 CLKGT-KVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEA 129 C K C+ F ++K ++E+ C+S+ +L + + D L + ++ Sbjct: 10 CPKNWICYKNNCYQFFDESKNWYESQASCMSQNASLLKVYSKEDQD-LLKLVKSYH---- 64 Query: 130 EIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRC 189 W+GL + G+W G+ ++ + +CA+ + + G + C Sbjct: 65 --WMGLVHIPTNGSWQWEDGSILS------PNLLTIIEMQKGDCALYASSFKGYIEN--C 114 Query: 190 RDQLPYIC 197 YIC Sbjct: 115 STPNTYIC 122 >1H8U-A nrPDB Length = 117 Score = 54.0 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 45/121 (37%), Gaps = 10/121 (8%) Query: 82 FLAFTQTKTFHEASEDCIS-RGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLG--LNDM 138 +L +TF +A C G L + + N + + S N+ ++W+G + Sbjct: 4 YLLVRSLQTFSQAWFTCRRCYRGNLVSIHNFNINYRIQCSV--SALNQGQVWIGGRITGS 61 Query: 139 AAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQ 198 + + G+R + W + +C L G W C +LP+IC Sbjct: 62 GRCRRFQWVDGSRWNFAYWAAHQPWS----RGGHCVALCTRG-GYWRRAHCLRRLPFICS 116 Query: 199 F 199 + Sbjct: 117 Y 117 >5B1R-A nrPDB Length = 127 Score = 35.9 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 13/99 (13%), Positives = 29/99 (29%), Gaps = 7/99 (7%) Query: 71 CLKGT-KVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEY---LRQSVG 126 C G +CF ++ E+ + C S L S+ L + + Sbjct: 5 CPSGWIPYQERCFYISHTLRSLEESQKYCTSLSSKLAAFDEPSKYYYEVSLPSGLEELLD 64 Query: 127 NEAEIWLGLNDMAA---EGTWVDMTGARIAYKNWETEIT 162 W+ ++ + + Y+ W+ + Sbjct: 65 RSKSYWIQMSKKWRHDYDSQSRYCDKIKKYYQKWKRTFS 103 >4TKO-B nrPDB Length = 358 Score = 28.6 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Query: 16 LTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQ 64 + ++ TE K K I NA+ + K EELK L +L +E+ LKE+ Sbjct: 165 IQEINTEIKRAK-KGIENARNEF---KTIEELKKELSSLEEEIKSLKER 209 >6EZN-A nrPDB Length = 476 Score = 28.6 bits (62), Expect = 1.9, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 23/56 (41%) Query: 4 WGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVA 59 W L LC F++ + EPP DV N + E ++ + +A E A Sbjct: 8 WIVGLFLCFFNVSSAAQYEPPATWENVDYKRTIDVSNAYISETIEITIKNIASEPA 63 >2I94-A nrPDB Length = 202 Score = 27.9 bits (60), Expect = 3.0, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 25/68 (36%), Gaps = 2/68 (2%) Query: 33 NAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFH 92 N+K ++ ++ EEL+ L+T E L Q+ C G + +++ Sbjct: 3 NSKSGALSKEILEELQ--LNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEA 60 Query: 93 EASEDCIS 100 + Sbjct: 61 DPKAYAQH 68 >1GOW-A nrPDB Length = 489 Score = 27.5 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 26/59 (44%) Query: 24 PTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCF 82 P +P+ +K+DV ++ E RLD A + AL ++ + + +G + Sbjct: 91 PLPRPQNFDESKQDVTEVEINENELKRLDEYANKDALNHYREIFKDLKSRGLYFIQNMY 149 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.122 0.379 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,900,891 Number of Sequences: 36641 Number of extensions: 267177 Number of successful extensions: 989 Number of sequences better than 10.0: 52 Number of HSP's better than 10.0 without gapping: 68 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 763 Number of HSP's gapped (non-prelim): 107 length of query: 202 length of database: 10,336,785 effective HSP length: 92 effective length of query: 110 effective length of database: 6,965,813 effective search space: 766239430 effective search space used: 766239430 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 56 (26.3 bits)