BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05202 (430 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3PD6-B nrPDB 843 0.0 1TAR-A nrPDB 753 0.0 2CST-A nrPDB 419 e-118 3II0-A nrPDB 405 e-113 5TON-A nrPDB 396 e-110 4W5K-A nrPDB 391 e-109 1YAA-A nrPDB 369 e-102 4RKC-A nrPDB 340 7e-94 6EZL-A nrPDB 339 1e-93 4WD2-A nrPDB 332 1e-91 4WB0-B nrPDB 331 4e-91 4H51-A nrPDB 324 4e-89 4EFF-A nrPDB 324 5e-89 4F5M-A nrPDB 324 5e-89 3FSL-A nrPDB 311 4e-85 3MEB-A nrPDB 308 3e-84 1AY8-A nrPDB 272 2e-73 3K7Y-A nrPDB 224 5e-59 3RQ1-A nrPDB 80 2e-15 4EMY-A nrPDB 60 2e-09 2X5F-A nrPDB 54 1e-07 6F77-B nrPDB 41 0.001 1V2E-A nrPDB 40 0.002 4MY5-A nrPDB 40 0.002 1J32-A nrPDB 40 0.002 1GDE-A nrPDB 39 0.004 2ZC0-A nrPDB 39 0.005 3ELE-A nrPDB 37 0.017 3QGU-A nrPDB 35 0.070 1O4S-A nrPDB 34 0.094 3EI8-A nrPDB 34 0.11 4FL0-A nrPDB 33 0.27 4CVQ-A nrPDB 32 0.58 5IX2-A nrPDB 30 2.0 3GET-A nrPDB 30 3.0 3ASB-A nrPDB 29 3.2 4NZ0-A nrPDB 29 3.3 1VP4-A nrPDB 29 4.7 1M4N-A nrPDB 29 4.8 >3PD6-B nrPDB Length = 401 Score = 843 bits (2177), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/401 (100%), Positives = 401/401 (100%) Query: 30 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA 89 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA Sbjct: 1 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA 60 Query: 90 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 149 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF Sbjct: 61 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 120 Query: 150 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL 209 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL Sbjct: 121 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL 180 Query: 210 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 269 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI Sbjct: 181 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 240 Query: 270 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 329 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT Sbjct: 241 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 300 Query: 330 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 389 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE Sbjct: 301 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 360 Query: 390 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK Sbjct: 361 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 401 >1TAR-A nrPDB Length = 401 Score = 753 bits (1945), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/401 (86%), Positives = 378/401 (94%) Query: 30 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA 89 SSWW+HVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVL VRKAEA IAA Sbjct: 1 SSWWSHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLNCVRKAEAMIAA 60 Query: 90 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 149 K +DKEYLPI GLA+F +ASAELALGEN+E KSGR+VTVQ ISGTG+LRVGA+FLQRFF Sbjct: 61 KKMDKEYLPIAGLADFTRASAELALGENSEAFKSGRYVTVQGISGTGSLRVGANFLQRFF 120 Query: 150 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL 209 KFSRDV+LPKPSWGNHTPIFRDAG+QLQ YRYYDPKTC DF+GA+EDISKIPE+S++LL Sbjct: 121 KFSRDVYLPKPSWGNHTPIFRDAGLQLQAYRYYDPKTCSLDFTGAMEDISKIPEKSIILL 180 Query: 210 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 269 HACAHNPTGVDPR EQWKE+ASVVKK+NL A+FDMAYQGFASGD ++DAWA+RHFIEQGI Sbjct: 181 HACAHNPTGVDPRQEQWKELASVVKKRNLLAYFDMAYQGFASGDINRDAWALRHFIEQGI 240 Query: 270 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 329 +V L QSYAKNMGLYGER GAFTV+C+DAEEAKRVESQLKILIRP+YSNPP+NGARIA+ Sbjct: 241 DVVLSQSYAKNMGLYGERAGAFTVICRDAEEAKRVESQLKILIRPMYSNPPMNGARIASL 300 Query: 330 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 389 IL +P+LRK+WL EVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE Sbjct: 301 ILNTPELRKEWLVEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 360 Query: 390 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 QVERLTKEFS+YMTKDGRISVAGV S NVGYLAHAIHQVTK Sbjct: 361 QVERLTKEFSIYMTKDGRISVAGVASSNVGYLAHAIHQVTK 401 >2CST-A nrPDB Length = 411 Score = 419 bits (1078), Expect = e-118, Method: Compositional matrix adjust. Identities = 203/409 (49%), Positives = 282/409 (68%), Gaps = 7/409 (1%) Query: 29 ASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIA 88 A+S + V PP + +T F+ D +S+K+NLGVGAYR D G+P+VLP VRK E IA Sbjct: 1 AASIFAAVPRAPPVAVFKLTADFREDGDSRKVNLGVGAYRTDEGQPWVLPVVRKVEQLIA 60 Query: 89 AK-NLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQR 147 +L+ EYLPI GL EF ++ +ALG+++ + R +VQ + GTGALR+GA FL+R Sbjct: 61 GDGSLNHEYLPILGLPEFRANASRIALGDDSPAIAQKRVGSVQGLGGTGALRIGAEFLRR 120 Query: 148 FFKFSRD----VFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALEDISKIP 202 ++ + + V++ P+W NH +F DAG + ++ YRY+D G D G L+D+ K P Sbjct: 121 WYNGNNNTATPVYVSSPTWENHNSVFMDAGFKDIRTYRYWDAAKRGLDLQGLLDDMEKAP 180 Query: 203 EQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVR 262 E S+ +LHACAHNPTG DP P++WK+IA+V+K++ LF FFD AYQGFASG DKDAWAVR Sbjct: 181 EFSIFILHACAHNPTGTDPTPDEWKQIAAVMKRRCLFPFFDSAYQGFASGSLDKDAWAVR 240 Query: 263 HFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLN 322 +F+ +G + QS++KN GLY ERVG +VV KD + +RV SQ++ ++R +SNPP Sbjct: 241 YFVSEGFELFCAQSFSKNFGLYNERVGNLSVVGKDEDNVQRVLSQMEKIVRTTWSNPPSQ 300 Query: 323 GARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFC 382 GARI AT LTSP L +W VK MADR++ MR++L S L+ G+ W HITDQIGMF Sbjct: 301 GARIVATTLTSPQLFAEWKDNVKTMADRVLLMRSELRSRLESLGTPGTWNHITDQIGMFS 360 Query: 383 FTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQ-VTK 430 FTGL P+QVE + KE +Y+ GRI++ G+T+ N+ Y+A +IH+ VTK Sbjct: 361 FTGLNPKQVEYMIKEKHIYLMASGRINMCGLTTKNLDYVAKSIHEAVTK 409 >3II0-A nrPDB Length = 422 Score = 405 bits (1040), Expect = e-113, Method: Compositional matrix adjust. Identities = 196/397 (49%), Positives = 276/397 (69%), Gaps = 7/397 (1%) Query: 41 PDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN-LDKEYLPI 99 P + +T F+ D + +K+NLGVGAYR D+ P+VLP V+K E +IA N L+ EYLPI Sbjct: 3 PVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPI 62 Query: 100 GGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRD----V 155 GLAEF ++ LALG+++ LK R VQ++ GTGALR+GA FL R++ + + V Sbjct: 63 LGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPV 122 Query: 156 FLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAH 214 ++ P+W NH +F AG + ++ YRY+D + G D G L D+ PE S+++LHACAH Sbjct: 123 YVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAH 182 Query: 215 NPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLC 274 NPTG+DP PEQWK+IASV+K + LF FFD AYQGFASG+ ++DAWA+R+F+ +G Sbjct: 183 NPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCA 242 Query: 275 QSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSP 334 QS++KN GLY ERVG TVV K+ E +V SQ++ ++R +SNPP GARI A+ L++P Sbjct: 243 QSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNP 302 Query: 335 DLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERL 394 +L ++W VK MADRI++MR++L + L+ + W HITDQIGMF FTGL P+QVE L Sbjct: 303 ELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYL 362 Query: 395 TKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQ-VTK 430 E +Y+ GRI+V+G+T+ N+ Y+A +IH+ VTK Sbjct: 363 VNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTK 399 >5TON-A nrPDB Length = 414 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 195/407 (47%), Positives = 274/407 (67%), Gaps = 7/407 (1%) Query: 31 SWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK 90 S + V P + + F+ D + +K+NLGVGAYR D+ +P+VLP VRK E +IA Sbjct: 6 SVFAEVPQAQPVLVFKLIADFREDPDPRKVNLGVGAYRTDDCQPWVLPVVRKVEQRIANN 65 Query: 91 N-LDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 149 + L+ EYLPI GLAEF ++ LALG+++ L+ R VQ++ GTGALR+GA FL R++ Sbjct: 66 SSLNHEYLPILGLAEFRTCASRLALGDDSPALQEKRVGGVQSLGGTGALRIGAEFLARWY 125 Query: 150 KFSRD----VFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALEDISKIPEQ 204 + + V++ P+W N +F AG + ++ YRY+D + G D G L D+ PE Sbjct: 126 NGTNNKDTPVYVSSPTWENLNGVFTTAGFKDIRSYRYWDTEKRGLDLQGFLSDLENAPEF 185 Query: 205 SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHF 264 S+ +LHACAHNPTG DP PEQWK+IASV+K++ LF FFD AYQGFASG+ +KDAWA+R+F Sbjct: 186 SIFVLHACAHNPTGTDPTPEQWKQIASVMKRRFLFPFFDSAYQGFASGNLEKDAWAIRYF 245 Query: 265 IEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGA 324 + +G + QS++KN GLY ERVG TVV K+ + RV SQ++ ++R +SNPP GA Sbjct: 246 VSEGFELFCAQSFSKNFGLYNERVGNLTVVAKEPDSILRVLSQMQKIVRVTWSNPPAQGA 305 Query: 325 RIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFT 384 RI A L+ P+L +W VK MADRI+SMR++L + L+ + W HITDQIGMF FT Sbjct: 306 RIVARTLSDPELFHEWTGNVKTMADRILSMRSELRARLEALKTPGTWNHITDQIGMFSFT 365 Query: 385 GLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQ-VTK 430 GL P+QVE L + +Y+ GRI++ G+T+ N+ Y+A +IH+ VTK Sbjct: 366 GLNPKQVEYLINQKHIYLLPSGRINMCGLTTKNLDYVATSIHEAVTK 412 >4W5K-A nrPDB Length = 396 Score = 391 bits (1005), Expect = e-109, Method: Compositional matrix adjust. Identities = 186/393 (47%), Positives = 253/393 (64%), Gaps = 5/393 (1%) Query: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97 MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y Sbjct: 9 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 63 Query: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157 P+ G+A F + + +L G L+ GR + QT+ GTGALR+G L RF ++ Sbjct: 64 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 123 Query: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217 P + NH IF AGM+L Y YYDP T G + +G LE + K PE SV+L+HACAHNPT Sbjct: 124 PDVGYPNHESIFAKAGMELTPYSYYDPATKGLNLAGMLECLDKAPEGSVILVHACAHNPT 183 Query: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277 GVDP + W+++ V+K++N F DMAYQGFA+G D DA+ RH ++ N+ + QS+ Sbjct: 184 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 243 Query: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLR 337 + N GLYG R GA + AEEAKR+ SQL +LIRP+YSNPPL GA + ++IL P L Sbjct: 244 SANFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 303 Query: 338 KQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKE 397 W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E Sbjct: 304 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 363 Query: 398 FSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 + +YMT +GR +V+G+ S NV Y++ AIH VTK Sbjct: 364 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 396 >1YAA-A nrPDB Length = 412 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 180/410 (43%), Positives = 261/410 (63%), Gaps = 9/410 (2%) Query: 29 ASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIA 88 +++ + ++E+ PPD + G+ + + +D + K++LG+GAYRDDNGKP+VLPSV+ AE I Sbjct: 1 SATLFNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIH 60 Query: 89 A-KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQR 147 + + EYL I GL +A++ G ++ L+ R ++VQ++SGTGAL + A F + Sbjct: 61 NDSSYNHEYLGITGLPSLTSNAAKIIFGTQSDALQEDRVISVQSLSGTGALHISAKFFSK 120 Query: 148 FFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVL 207 FF + V+L KP+W NH IF + G++ Y Y+ +T D +G L I K PE S+ Sbjct: 121 FFP-DKLVYLSKPTWANHMAIFENQGLKTATYPYWANETKSLDLNGFLNAIQKAPEGSIF 179 Query: 208 LLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQ 267 +LH+CAHNPTG+DP EQW +I + KN A FD AYQGFA+GD DKDA+AVR +E+ Sbjct: 180 VLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVRLGVEK 239 Query: 268 GINVC---LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVE----SQLKILIRPLYSNPP 320 V +CQS+AKN G+YGERVG F + + K ++ SQL +IR SNPP Sbjct: 240 LSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSEVSNPP 299 Query: 321 LNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGM 380 GA+I A +L +P+L +QW +++ M+ RI MR L +L K G+ NW HI +Q GM Sbjct: 300 AYGAKIVAKLLETPELTEQWHKDMVTMSSRITKMRHALRDHLVKLGTPGNWDHIVNQCGM 359 Query: 381 FCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 F FTGL P+ V+RL + +VY+ GR S+AG+ GNV Y+A AI +V + Sbjct: 360 FSFTGLTPQMVKRLEETHAVYLVASGRASIAGLNQGNVEYVAKAIDEVVR 409 >4RKC-A nrPDB Length = 398 Score = 340 bits (872), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 170/389 (43%), Positives = 239/389 (61%), Gaps = 2/389 (0%) Query: 42 DPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGG 101 DPILG+ E F D N K+NLG+G Y D++G VL V+ AE +IA + YLP+ G Sbjct: 11 DPILGLVEKFAADNNPDKVNLGIGIYYDESGVMPVLDCVKIAEQRIADPISPRPYLPMAG 70 Query: 102 LAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPS 161 L K EL G++ VLK G T+ TI G+GAL+VGA F+ +F S+ ++ P+ Sbjct: 71 LPGHRKGCQELLFGKDAPVLKDGLVATIATIGGSGALKVGAEFIHEWFPQSK-CYVSDPT 129 Query: 162 WGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDP 221 WGNH IF +++ Y YYD T G F + + + VLLLH C HNPTGVD Sbjct: 130 WGNHIAIFEGCDIEVGKYPYYDTATGGIKFDEMIAFFETLNKDDVLLLHPCCHNPTGVDL 189 Query: 222 RPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNM 281 EQW + +V++++ L F D+AYQGF D D DA+A+R ++ G+ + + S++KN+ Sbjct: 190 TREQWDTVLNVIQERELIPFMDIAYQGFGE-DMDSDAYAIRKAVDMGLPLFVSNSFSKNL 248 Query: 282 GLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWL 341 LYGERVG +VVC +E +RV QL +R +YS+PP +G R+ ++ L +QW+ Sbjct: 249 SLYGERVGGLSVVCPTVDETERVFGQLNSTVRRIYSSPPSHGGRVVDIVMNDAALHEQWV 308 Query: 342 QEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVY 401 EV M DRI SMRT+L S L+ + S N+ ++T Q GMF FTGL PEQVERL EF +Y Sbjct: 309 GEVYAMRDRIKSMRTKLKSVLEAKISGRNFDYLTAQNGMFSFTGLTPEQVERLQSEFGIY 368 Query: 402 MTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 M + R+ VAG+ S N+ Y+A+A+ V K Sbjct: 369 MISNSRMCVAGLNSSNIDYVANAMVDVLK 397 >6EZL-A nrPDB Length = 404 Score = 339 bits (870), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 168/399 (42%), Positives = 245/399 (61%), Gaps = 6/399 (1%) Query: 33 WTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNL 92 W ++ P DPI + K+ K +L +GAYRD G PY L VRKAE ++ N Sbjct: 7 WNNIAALPADPIFSASLVAKK-APEPKADLIIGAYRDAEGHPYPLNVVRKAEQRLLEMNA 65 Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 DKEYLP+ G A F + S ++A G++ + V +Q +SGTG+L +GA FL R Sbjct: 66 DKEYLPMSGYAPFIEESLKIAYGDS---VARENVVGIQGLSGTGSLSIGACFLARVLSRD 122 Query: 153 RDVFLPKPSWGNHTPIFRDAGM-QLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHA 211 V++ P+W NH + A + L+ YRYYD DF G LED++ PE S+++LHA Sbjct: 123 TPVYISDPTWPNHYAVMAAANLTDLRKYRYYDNAKRCIDFDGLLEDLNGAPEGSIVILHA 182 Query: 212 CAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINV 271 CAHNPTG+DP EQW +I V + + L FFD AYQG+A+G D DA+++R F QG+ + Sbjct: 183 CAHNPTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGMEM 242 Query: 272 CLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATIL 331 L QSY+KNMGLY ERVG ++V + ++A ++SQL+ ++R YS PP +GAR+A +L Sbjct: 243 LLAQSYSKNMGLYAERVGVCSIVTANPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLVL 302 Query: 332 TSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQV 391 + P+LR W QE++ M+ R++ MR L LK+ G+ +W+HI Q+GMF + GL Q Sbjct: 303 SDPELRAGWEQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGLTKAQC 362 Query: 392 ERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 E+L E V++ GR ++AG+T +V L I +V + Sbjct: 363 EKLI-ERRVFVLPSGRANMAGLTKRSVELLVKGIDEVVR 400 >4WD2-A nrPDB Length = 408 Score = 332 bits (852), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 170/398 (42%), Positives = 237/398 (59%), Gaps = 2/398 (0%) Query: 33 WTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNL 92 + H++ P DPIL + E F++D +K+NL +G Y D G+ V+ +VR+AE + + Sbjct: 10 FEHIDAYPGDPILTLNENFQKDPRDQKVNLSIGIYFDAEGRIPVMGAVREAETALQRDSG 69 Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 K YLP+ GLA + A L G ++ +GR T+QT+ G+GAL+VGA FL+R+F S Sbjct: 70 PKPYLPMVGLAAYRDAVQSLVFGADHPARAAGRIATLQTLGGSGALKVGADFLKRYFPDS 129 Query: 153 RDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHAC 212 + V+L PSW NH IF AG + Y YYD T G F L I +P +S++LLHAC Sbjct: 130 Q-VWLSDPSWENHRFIFERAGFTVNTYPYYDEATGGLKFDAMLAAIDALPARSIVLLHAC 188 Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC 272 HNPTGVD QW+++ V++ + L F DMAYQGF +G D DA+AVR +G+ Sbjct: 189 CHNPTGVDLDEGQWEKLIDVIEARELLPFVDMAYQGFGAGL-DADAFAVRELARRGVPTL 247 Query: 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILT 332 + S++KN LYGERVG +VVC+DA A+RV QL +R YSNP GA++ A +L Sbjct: 248 VANSFSKNFSLYGERVGGLSVVCEDAAAAERVLGQLAGAVRSNYSNPQTYGAKVVAAVLG 307 Query: 333 SPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVE 392 +P LRKQW +E+ M RI MR + L+ S Q GMF +TGL QV+ Sbjct: 308 TPALRKQWEEELSAMCRRIARMRQSIHDGLRDHVSGEALTRYVKQRGMFTYTGLTESQVD 367 Query: 393 RLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 L + VY+ + GR+ VAG+ NVG +A AI +V K Sbjct: 368 ALREVHGVYILRSGRMCVAGLNDSNVGIVADAIGKVLK 405 >4WB0-B nrPDB Length = 414 Score = 331 bits (848), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 177/414 (42%), Positives = 245/414 (59%), Gaps = 11/414 (2%) Query: 21 LAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSK--KMNLGVGAYRDDNGKPYVLP 78 ++ A+ + W ++ PDPI E KR +K K NL +GAYRD+ G PY L Sbjct: 3 MSTQAAMTTTERWQKIQGRAPDPIF---ELAKRAAAAKGPKANLVIGAYRDEQGLPYPLR 59 Query: 79 SVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGAL 138 VRKAE + NL+ EYLPI G F + ++ G+ E+ V VQT+SGTGAL Sbjct: 60 VVRKAEQLLLDMNLNYEYLPISGYQPFIDEAVKMTYGDTVEL---ENLVAVQTLSGTGAL 116 Query: 139 RVGASFLQRFFKFSRD-VFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALE 196 +GA L F + ++L P+W NH I + AG + ++ Y YYD KT G DF G + Sbjct: 117 SLGAKLLTHVFDAEKTPIYLADPTWPNHYSIVKAAGWKDIRTYAYYDHKTLGLDFEGMKK 176 Query: 197 DISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDK 256 DI P+ SV LLH CAHNPTGVDP EQW EIAS++ K+ FFD AYQG+ASG D Sbjct: 177 DILAAPDGSVFLLHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDT 236 Query: 257 DAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLY 316 DA+A R F +GI V L QS++KNMGLY ER G +++ KD + V+S + LIR Y Sbjct: 237 DAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDSLIRAEY 296 Query: 317 SNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITD 376 + PP +GAR+A IL++ +LRK+W E+ MA+RI +MR + L + + W+H+ + Sbjct: 297 TCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQTPGRWEHVIN 356 Query: 377 QIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 QIGMF F GL EQ E + ++++T GR ++AG+T LA I+ + Sbjct: 357 QIGMFSFLGLSKEQCE-YCQNHNIFITLSGRANIAGLTHETALMLAQTINDAVR 409 >4H51-A nrPDB Length = 420 Score = 324 bits (831), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 175/422 (41%), Positives = 247/422 (58%), Gaps = 11/422 (2%) Query: 13 MAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSK--KMNLGVGAYRDD 70 MA H ++ A+ + W ++ PD I + KR +K K NL +GAYRD+ Sbjct: 1 MAHHHHHHMSTQAAMTTAERWQKIQAQAPDVIFDLA---KRAAAAKGPKANLVIGAYRDE 57 Query: 71 NGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQ 130 G+PY L VRKAE + NLD EYLPI G F + ++ G E+ V VQ Sbjct: 58 QGRPYPLRVVRKAEQLLLDMNLDYEYLPISGYQPFIDEAVKIIYGNTVEL---ENLVAVQ 114 Query: 131 TISGTGALRVGASFLQRFFKF-SRDVFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCG 188 T+SGTGA+ +GA L R F + ++L P+W NH + + AG + + Y YYDPKT Sbjct: 115 TLSGTGAVSLGAKLLTRVFDAETTPIYLSDPTWPNHYGVVKAAGWKNICTYAYYDPKTVS 174 Query: 189 FDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQG 248 +F G +DI P+ SV +LH CAHNPTGVDP EQW EIAS++ K+ FFD AYQG Sbjct: 175 LNFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQG 234 Query: 249 FASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQL 308 +ASG D DA+A R F +GI V L QS++KNMGLY ER G +++ KD + V+S + Sbjct: 235 YASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVM 294 Query: 309 KILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSS 368 LIR Y+ PP +GAR+A IL++ +LRK+W E+ MA+RI +MR + L + + Sbjct: 295 DSLIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQTP 354 Query: 369 HNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQV 428 +W+H+ +QIGMF F GL Q E + ++++T GR ++AG+T LA I+ Sbjct: 355 GSWEHVINQIGMFSFLGLSKAQCE-YCQNHNIFITVSGRANMAGLTHETALMLAQTINDA 413 Query: 429 TK 430 + Sbjct: 414 VR 415 >4EFF-A nrPDB Length = 420 Score = 324 bits (830), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 176/400 (44%), Positives = 244/400 (61%), Gaps = 2/400 (0%) Query: 31 SWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK 90 S ++ VE+ P DPILG+ EAF DT K+NLGVG Y +++GK +L +VR AE Sbjct: 23 SLFSAVELAPRDPILGLNEAFNADTRPTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVEA 82 Query: 91 NLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFK 150 L + YLPI G+A + + +L LG+++ ++ +GR VT Q + GTGAL++GA FL R Sbjct: 83 GLPRGYLPIDGIAAYDASVQKLLLGDDSPLIAAGRVVTAQALGGTGALKIGADFL-RTLN 141 Query: 151 FSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLH 210 V + PSW NH +F AG ++ Y YYD KT G +F G L ++ ++++LH Sbjct: 142 PKAKVAISDPSWENHRALFDMAGFEVVAYPYYDAKTNGVNFDGMLAALNGYEPGTIVVLH 201 Query: 211 ACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN 270 AC HNPTGVD QW ++ VVK + L F D+AYQGF + DA AVR F +N Sbjct: 202 ACCHNPTGVDLNDAQWAQVVEVVKARRLVPFLDIAYQGFGESI-EADAAAVRLFAAANLN 260 Query: 271 VCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATI 330 V + S++K+ LYGERVGA +++ +EA RV SQLK +IR YSNPP +G I A + Sbjct: 261 VFVSSSFSKSFSLYGERVGALSIITDSKDEAARVLSQLKRVIRTNYSNPPTHGGAIVAAV 320 Query: 331 LTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQ 390 L SP+LR W+QE+ M DRI +MR LV LK G ++ I Q GMF ++GL Q Sbjct: 321 LASPELRASWVQELGEMRDRIRAMRNGLVERLKAAGIERDFSFINAQRGMFSYSGLTSAQ 380 Query: 391 VERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 V+RL +EF +Y GRI VA + + N+ +A+AI V K Sbjct: 381 VDRLREEFGIYAVSTGRICVAALNTRNLDVVANAIAAVLK 420 >4F5M-A nrPDB Length = 406 Score = 324 bits (830), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 167/396 (42%), Positives = 233/396 (58%), Gaps = 2/396 (0%) Query: 33 WTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNL 92 + ++ P DPILG+ + F+ D K+NLG+G Y+D+ GK VL SV+KAE + Sbjct: 12 FENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLENET 71 Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 K YL I G+ EF + + EL G+ + ++ R T QT GTGALRV A FL + Sbjct: 72 TKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKNTSVK 131 Query: 153 RDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHAC 212 R V++ PSW NH +F AG++++ Y YYD + DF + +++ V+L H C Sbjct: 132 R-VWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFDALINSLNEAQAGDVVLFHGC 190 Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC 272 HNPTG+DP EQW+ +A + +K FD AYQGFA G ++DA +R F + Sbjct: 191 CHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARG-LEEDAEGLRAFAAMHKELI 249 Query: 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILT 332 + SY+KN GLY ERVGA T+V D+E R SQ+K IR YSNPP +GA + ATIL+ Sbjct: 250 VASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNPPAHGASVVATILS 309 Query: 333 SPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVE 392 + LR W QE+ M RI MR V+ L+++G++ ++ I Q GMF F+GL EQV Sbjct: 310 NDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKEQVL 369 Query: 393 RLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQV 428 RL +EF VY GR++VAG+T N+ L AI V Sbjct: 370 RLREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAV 405 >3FSL-A nrPDB Length = 397 Score = 311 bits (796), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 162/388 (41%), Positives = 235/388 (60%), Gaps = 3/388 (0%) Query: 42 DPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKE-YLPIG 100 DPIL + E FK D S K+NL +G Y +++G L +V +AEA++ A+ YLP+ Sbjct: 11 DPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQPHGASLYLPME 70 Query: 101 GLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKP 160 GL + A A L G ++ VLK R T+QT+ G+GAL+VGA FL+R+F S V++ P Sbjct: 71 GLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFPES-GVWVSDP 129 Query: 161 SWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVD 220 +W NH IF AG ++ Y +YD T G F+ L + + S++LLH C HNPTG D Sbjct: 130 TWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLATLKTLQAGSIVLLHPCCHNPTGAD 189 Query: 221 PRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKN 280 +QW + ++K + L F D+AYQGF +G ++DA+A+R G+ + S++K Sbjct: 190 LTNDQWDAVIEILKARELIPFLDIAYQGFGAG-MEEDAYAIRAIASAGLPALVSNSFSKI 248 Query: 281 MGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQW 340 LYGERVG +V+C+DAE A RV QLK +R YS+PP GA++ A +L L+ W Sbjct: 249 FSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVLNDEALKASW 308 Query: 341 LQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSV 400 L+EV+ M RI++MR +LV L E N+ ++ +Q GMF +TGL QV+RL +EF V Sbjct: 309 LKEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGV 368 Query: 401 YMTKDGRISVAGVTSGNVGYLAHAIHQV 428 Y+ GR+ VAG+ + NV +A A V Sbjct: 369 YLIASGRMCVAGLNTANVQRVAKAFAAV 396 >3MEB-A nrPDB Length = 448 Score = 308 bits (789), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 168/413 (40%), Positives = 247/413 (59%), Gaps = 23/413 (5%) Query: 40 PPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA--KNLDKEYL 97 PPD IL +T + DTN KK+NLGVGAYRD++GKP++LP+V++AEA I++ +KEY Sbjct: 32 PPDAILNLTVLYNADTNPKKVNLGVGAYRDESGKPWILPAVKEAEAIISSDLSKYNKEYP 91 Query: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157 P+ G F +A+ L G++++ + GR + Q++SGTG+L +G FL + + ++ Sbjct: 92 PVAGFPLFLEAAQFLMFGKDSKAAQEGRIASCQSLSGTGSLHIGFEFLHLWMP-KAEFYM 150 Query: 158 PKPSWGNHTPIFRDAGMQLQ-GYRYY----DPKTCGFDFSGALEDISKIPEQSVLLLHAC 212 P +W NH I+ +L+ Y+ Y DFS +DI PE+S+ L HAC Sbjct: 151 PSTTWPNHYGIYDKVFNKLKVPYKEYTYLRKDGELEIDFSNTKKDIQSAPEKSIFLFHAC 210 Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC 272 AHNP+G+D QWKE+ ++K+K AFFD AYQGFA+G + DA+AVR F++ G+ V Sbjct: 211 AHNPSGIDFTEAQWKELLPIMKEKKHIAFFDSAYQGFATGSFEADAFAVRMFVDAGVEVL 270 Query: 273 LCQSYAKNMGLYGERVGAFTVVC--------KDAEEAKRVESQLKILIRPLYSNPPLNGA 324 + QS++KN GLYGER+G VV K+ + + S + + IR +S ++GA Sbjct: 271 VAQSFSKNFGLYGERIGCLHVVHAGVEGSVEKNKALSAAMVSGMTLQIRKTWSMSAIHGA 330 Query: 325 RIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKE-----GSSHNWQHITDQIG 379 I I+ L + + VK M+ RI MR+ L ++L K GS W HI IG Sbjct: 331 YIVQVIVHDKRLLQMFYDNVKEMSARIHRMRSLLHASLAKRKTPGPGSKGTWDHILTAIG 390 Query: 380 MFCFTGLKPEQVERLTKEFSVYMTK-DGRISVAGVTSGNVGYLAHAIHQ-VTK 430 MF FTGL PE V+ L +++S+Y+ K GR+S+ G+T N Y+A AIH VTK Sbjct: 391 MFTFTGLTPEHVDYLKEKWSIYLVKAGGRMSMCGLTESNCDYVAEAIHDAVTK 443 >1AY8-A nrPDB Length = 394 Score = 272 bits (696), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 146/389 (37%), Positives = 213/389 (54%), Gaps = 7/389 (1%) Query: 41 PDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIG 100 PD IL + F+ D K++LGVG Y+D G ++ +V AE ++ K Y + Sbjct: 10 PDKILALMGEFRADPRQGKIDLGVGVYKDATGHTPIMRAVHAAEQRMLETETTKTYAGLS 69 Query: 101 GLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKP 160 G EF KA EL LG+ LKS T+ T+ GTGALR A L R VF+ P Sbjct: 70 GEPEFQKAMGELILGDG---LKSETTATLATVGGTGALRQ-ALELARMANPDLRVFVSDP 125 Query: 161 SWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVD 220 +W NH I G+ +Q YRY+D +T G DF G D++ + ++LLH C HNPTG + Sbjct: 126 TWPNHVSIMNFMGLPVQTYRYFDAETRGVDFEGMKADLAAAKKGDMVLLHGCCHNPTGAN 185 Query: 221 PRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDG-DKDAWAVRHFIEQGINVCLCQSYAK 279 +QW EIAS+++K D+AYQGF GDG ++DA R + V + S +K Sbjct: 186 LTLDQWAEIASILEKTGALPLIDLAYQGF--GDGLEEDAAGTRLIASRIPEVLIAASCSK 243 Query: 280 NMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQ 339 N G+Y ER G +C DA + + + L R YS PP +GA+I +T+LT+P+LR Sbjct: 244 NFGIYRERTGCLLALCADAATRELAQGAMAFLNRQTYSFPPFHGAKIVSTVLTTPELRAD 303 Query: 340 WLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFS 399 W+ E++ + ++ +R QL L+ S + + + GMF G PEQV+R+ +EF Sbjct: 304 WMAELEAVRSGMLRLREQLAGELRDLSGSDRFGFVAEHRGMFSRLGATPEQVKRIKEEFG 363 Query: 400 VYMTKDGRISVAGVTSGNVGYLAHAIHQV 428 +YM D RI++AG+ + LA AI +V Sbjct: 364 IYMVGDSRINIAGLNDNTIPILARAIIEV 392 >3K7Y-A nrPDB Length = 405 Score = 224 bits (572), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 124/394 (31%), Positives = 203/394 (51%), Gaps = 7/394 (1%) Query: 36 VEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKE 95 +E D IL FK DT +K+NL +G +D+G ++ SV A+ + +K Sbjct: 8 LENIEVDNILKTAREFKEDTCEEKINLSIGVCCNDDGDLHIFDSVLNADKLVTENYKEKP 67 Query: 96 YLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDV 155 YL G +F + L G N++ ++ + T+Q I GTGA+ V FL+ + Sbjct: 68 YLLGNGTEDFSTLTQNLIFGNNSKYIEDKKICTIQCIGGTGAIFVLLEFLKMLN--VETL 125 Query: 156 FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHN 215 ++ P + NH + G L+ ++D ++ L D+ IP S ++L +N Sbjct: 126 YVTNPPYINHVNMIESRGFNLKYINFFDYNLIDINYDLFLNDLRNIPNGSSVILQISCYN 185 Query: 216 PTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQ 275 P V+ + + EI +V K FD+AYQGF + ++D +R F E+ I +CQ Sbjct: 186 PCSVNIEEKYFDEIIEIVLHKKHVIIFDIAYQGFGHTNLEEDVLLIRKFEEKNIAFSVCQ 245 Query: 276 SYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPD 335 S++KNM LYGER GA +VCK+ EE K V + L ++R YS+P ++ RI +L + + Sbjct: 246 SFSKNMSLYGERAGALHIVCKNQEEKKIVFNNLCFIVRKFYSSPVIHTNRILCQLLNNQN 305 Query: 336 LRKQWLQEVKGMADRIISMRTQLVSNL----KKEGSSHNWQHITDQIGMFCFTGLKPEQV 391 L+ W++E+ ++ RI + R + L KK +++W Q G+F F L + Sbjct: 306 LKLNWIKELSQLSQRITNNRILFFNKLETYQKKYNLNYDWNVYKKQRGLFSFVPLLAKIA 365 Query: 392 ERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAI 425 E L K +Y+ +GRI+V+G+T NV Y+A I Sbjct: 366 EHL-KTHHIYIINNGRINVSGITKNNVDYIADKI 398 >3RQ1-A nrPDB Length = 418 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 93/401 (23%), Positives = 159/401 (39%), Gaps = 42/401 (10%) Query: 52 KRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKE---YLPIGGLAEFCKA 108 K + +N +GA D+ G L +V++ ++ D E Y PI G+ +F A Sbjct: 33 KENGRENVVNGTLGAIHDEEGNLVFLKTVKEEYLSLS----DSEHVGYAPIAGIPDFLCA 88 Query: 109 SAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPI 168 + + G G ++ T GTG + + + + +V WG + I Sbjct: 89 AEKECFGN---FRPEGHIRSIATAGGTGGIH---HLIHNYTEPGDEVLTADWYWGAYRVI 142 Query: 169 FRDAGMQLQGYRYYDPKTCGFD---FSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQ 225 D G L Y +D F+ F + +++ V++ + +NPTG + Sbjct: 143 CSDTGRTLVTYSLFDEHN-NFNHEAFQNRVNELAAKQTNVVVIFNTPGNNPTGYSIEDKD 201 Query: 226 WKEIASVVK------KKNLFAFFDMAYQGFASGDGDKDAWAVRHF------IEQGINVCL 273 W I + +K + N+ D+AY ++ G+KD VR F + + I C+ Sbjct: 202 WDSILNFLKDLVAIGRNNVIIGIDVAYLDYS---GEKDE--VRAFFNKFSHLPKEILTCV 256 Query: 274 CQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTS 333 C S +K +YG+RVGA + D E A K R +SN R A I+ Sbjct: 257 CYSLSKGFTMYGQRVGAMIGISDDEEIADEFFEVNKSTSRATWSNICRPAMRTMANIVAD 316 Query: 334 PDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCF--TGLKPEQV 391 P K++ E + ++I R + K+E + + + G F T Sbjct: 317 PAKFKEYEAE-RNCYYQLIRDRADI---FKQEAAQVGLPMLPYRGGFFITIPTDSANAIC 372 Query: 392 ERLTKE--FSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 E L KE + + + RI+ G+ + LA I+ K Sbjct: 373 EELKKEHIYVIALANGIRIAACGIPKCQMTGLAEKIYNAMK 413 >4EMY-A nrPDB Length = 413 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 91/375 (24%), Positives = 154/375 (41%), Gaps = 41/375 (10%) Query: 60 MNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNE 119 +N +G DD GK LPSV ++ ++ Y PI G ++ K + G Sbjct: 40 INAALGTLLDDKGKIIALPSVYDRLDEMDRSHI-ASYAPIEGEKDYRKIVIDTLFGPYK- 97 Query: 120 VLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGY 179 G + T GTGA+R S + + + W + I + G + + Sbjct: 98 --PEGYISAIATPGGTGAIR---SAIFSYLDEGDPLICHDYYWAPYRKICEEFGRNFKTF 152 Query: 180 RYY-DPKTCGFD-FSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVV---- 233 ++ D D + A+++ + ++ L+++ +NPTG E+W E+ + + Sbjct: 153 EFFTDDFAFNIDVYKEAIDEGIRDSDRIASLINSPGNNPTGYSLSDEEWDEVITFLKEKA 212 Query: 234 --KKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYG 285 K K + D+AY FA GDGD+ R F E+ N V + S +K+ YG Sbjct: 213 EDKDKKITLIVDVAYLEFA-GDGDQQ----RKFFEKFSNLPRNLFVVVAFSMSKSHTAYG 267 Query: 286 ERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTS---PDLRKQWLQ 342 R GA + E + E+ L R +S NG A IL + +K + Q Sbjct: 268 LRSGAAVGISSSKEIIEEFEASLAHSARCNWS----NGTHAAQNILIELERAENKKIYEQ 323 Query: 343 EVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCF--TGLKPEQVERLTKE--F 398 E+ + + + S V+ K+ + I G F F T + V+ L KE F Sbjct: 324 ELVDLRNMLKSRADVFVTAAKE----NKLTMIPYFGGFFTFIPTDKAFDIVKDLEKENIF 379 Query: 399 SVYMTKDGRISVAGV 413 ++ K R+++ GV Sbjct: 380 TIPSAKGIRVAICGV 394 >2X5F-A nrPDB Length = 430 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 11/226 (4%) Query: 135 TGALRVGASFLQRFFKFSRD-VFLPKPSWGNHTPIFRD-AGMQLQGYRYYDPKTCGFDFS 192 T AL G S + F D + LP+ +WGN+ +F G LQ Y +D K + Sbjct: 119 TNALTHGLSLVGDLFVNQDDTILLPEHNWGNYKLVFNTRNGANLQTYPIFD-KDGHYTTD 177 Query: 193 GALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKK-----KNLFAFFDMAYQ 247 +E + + V+++ +NPTG P ++ I +K + A D AY Sbjct: 178 SLVEALQSYNKDKVIMILNYPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYY 237 Query: 248 GFASGDGDKDAW--AVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVE 305 G D + A+ + I K +G RVG T D + +E Sbjct: 238 GLFYEDVYTQSLFTALTNLHSNAILPIRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLE 297 Query: 306 SQLKILIRPLYSNPPLNGARIAATIL-TSPDLRKQWLQEVKGMADR 350 +++K LIR S+ PL +L + K+ Q ++ + +R Sbjct: 298 AKVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKER 343 >6F77-B nrPDB Length = 400 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 15/215 (6%) Query: 41 PDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIG 100 P + V++ + + +G+GA D P +++KA A A + +Y P+ Sbjct: 13 PSATIAVSQKARELKAKGRDVIGLGAGEPDFDTP---DNIKKA-AIDAIDRGETKYTPVS 68 Query: 101 GLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKP 160 G+ E +A A+ ENN + QTI GTG ++ + +V +P P Sbjct: 69 GIPELREAIAKKFKRENNL-----DYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAP 123 Query: 161 SWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISK-IPEQSVLLLHACAHNPTGV 219 W ++ + G G + P +F ED+ + I ++ + NP+G Sbjct: 124 YWVSYPEMVALCG----GTPVFVPTRQENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGA 179 Query: 220 DPRPEQWKEIASVV-KKKNLFAFFDMAYQGFASGD 253 E+ K + V+ K +++ D Y+ GD Sbjct: 180 AYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGD 214 >1V2E-A nrPDB Length = 381 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 62/235 (26%), Positives = 97/235 (41%), Gaps = 35/235 (14%) Query: 60 MNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAE-LALGENN 118 +NLG G + + P++L +VR+A + +Y P GL +A AE A+ + Sbjct: 28 VNLGQG-FPSNPPPPFLLEAVRRALGR------QDQYAPPAGLPALREALAEEFAVEPES 80 Query: 119 EVLKSGR----FVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGM 174 V+ SG +V +Q++ G G V L+ FF DV+LP + Sbjct: 81 VVVTSGATEALYVLLQSLVGPGDEVV---VLEPFF----DVYLPDAFLAGAKARLVRLDL 133 Query: 175 QLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVK 234 +G+R D S ALE + P LLL+ NPTG+ + + IA + + Sbjct: 134 TPEGFR--------LDLS-ALEK-ALTPRTRALLLN-TPMNPTGLVFGERELEAIARLAR 182 Query: 235 KKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 +LF D Y G+ + +R F + S K + G RVG Sbjct: 183 AHDLFLISDEVYDELYYGERPRR---LREFAPE--RTFTVGSAGKRLEATGYRVG 232 >4MY5-A nrPDB Length = 393 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 46/187 (24%), Positives = 75/187 (40%), Gaps = 20/187 (10%) Query: 105 FCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGN 164 F K L +NE+L TI T AL ++ L + V LP P++ Sbjct: 81 FVKEKYHLTYNPDNEIL--------VTIGATEAL---SASLTAILEPGDKVLLPAPAYPG 129 Query: 165 HTPIFRDAGMQLQGYRYYDPKTCGFDFSGAL--EDISKIPEQSVLLLHACAHNPTGVDPR 222 + P+ G ++ D ++ F + + E I K E ++ NPTGV Sbjct: 130 YEPVVNLVGAEVVEI---DTRSNDFVLTPEMLEEAILKEGEALKAVILNYPTNPTGVTYS 186 Query: 223 PEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMG 282 +Q K +A V+KK +F D Y + G+ + +Q I L +K+ Sbjct: 187 RQQIKNLAEVLKKYPIFVISDEVYAEL-TYTGESHVSIAEYLPDQTI---LISGLSKSHA 242 Query: 283 LYGERVG 289 + G R+G Sbjct: 243 MTGWRLG 249 >1J32-A nrPDB Length = 388 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 60/139 (43%), Gaps = 10/139 (7%) Query: 154 DVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISK-IPEQSVLLLHAC 212 +V +P P W ++ + + A +G P T F + E I + I ++ LL+ Sbjct: 116 EVIIPAPFWVSYPEMVKLA----EGTPVILPTTVETQFKVSPEQIRQAITPKTKLLVFNT 171 Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAW--AVRHFIEQGIN 270 NPTG+ P++ + IA V + L+ D Y+ D + A E+ + Sbjct: 172 PSNPTGMVYTPDEVRAIAQVAVEAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYERSV- 230 Query: 271 VCLCQSYAKNMGLYGERVG 289 +C +AK + G RVG Sbjct: 231 --VCSGFAKTYAMTGWRVG 247 >1GDE-A nrPDB Length = 389 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 16/209 (7%) Query: 86 QIAAKNLDK---EYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGA 142 + A + LDK Y P GL E +A AE L + N + + + + A +G Sbjct: 46 EYAKEALDKGLTHYGPNIGLLELREAIAE-KLKKQNGIEADPKTEIMVLLGANQAFLMG- 103 Query: 143 SFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISK-I 201 L F K +V +P P++ ++ P AG G P +F ++++ K + Sbjct: 104 --LSAFLKDGEEVLIPTPAFVSYAPAVILAG----GKPVEVPTYEEDEFRLNVDELKKYV 157 Query: 202 PEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWA- 260 +++ L+ NPTG + +EIA V + +L D Y+ F D + A Sbjct: 158 TDKTRALIINSPCNPTGAVLTKKDLEEIADFVVEHDLIVISDEVYEHFIYDDARHYSIAS 217 Query: 261 VRHFIEQGINVCLCQSYAKNMGLYGERVG 289 + E+ I V ++K + G R+G Sbjct: 218 LDGMFERTITV---NGFSKTFAMTGWRLG 243 >2ZC0-A nrPDB Length = 407 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 57/204 (27%), Positives = 77/204 (37%), Gaps = 45/204 (22%) Query: 74 PYVLPSVRKAEAQIAAKNLDKE-----YLPIGG-------LAEFCKASAELALGENNEVL 121 P ++P R +IA + L+KE Y P G LA F K L + N V+ Sbjct: 46 PELIP--RAVLGEIAKEVLEKEPKSVMYTPANGIPELREELAAFLKKYDHLEVSPENIVI 103 Query: 122 KSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPK-PSWGNHTPIFRDAGMQLQGYR 180 TI GTGAL L R DV + + PS+ N F G +++G Sbjct: 104 ---------TIGGTGAL----DLLGRVLIDPGDVVITENPSYINTLLAFEQLGAKIEG-- 148 Query: 181 YYDPKTCGFDFSGALEDI--SKIPE-----QSVLLLHAC--AHNPTGVDPRPEQWKEIAS 231 D G D+ KI E Q V L++ NP GV E+ K + Sbjct: 149 ------VPVDNDGMRVDLLEEKIKELKAKGQKVKLIYTIPTGQNPMGVTMSMERRKALLE 202 Query: 232 VVKKKNLFAFFDMAYQGFASGDGD 255 + K +L D AY GD Sbjct: 203 IASKYDLLIIEDTAYNFMRYEGGD 226 >3ELE-A nrPDB Length = 398 Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust. Identities = 42/176 (23%), Positives = 79/176 (44%), Gaps = 35/176 (19%) Query: 214 HNPTGVDPRPEQWKEIASVVKKKN------LFAFFDMAYQGFASGDGDKDAWAVRHFIEQ 267 +NP+G E K+++ +++KK+ +F D Y+ DG K + +++ Sbjct: 182 NNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVY-DGIKVPFVTKYYD-- 238 Query: 268 GINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIA 327 N +C SY+K++ L GER+G V + ++A+ LY+ + GA A Sbjct: 239 --NTLVCYSYSKSLSLPGERIGYVLVPDEVYDKAE------------LYA--AVCGAGRA 282 Query: 328 ATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCF 383 + +P L ++ + + +G I N KE ++ +T +IG CF Sbjct: 283 LGYVCAPSLFQKMIVKCQGATGDI---------NAYKENRDLLYEGLT-RIGYHCF 328 >3QGU-A nrPDB Length = 449 Score = 35.0 bits (79), Expect = 0.070, Method: Compositional matrix adjust. Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 6/101 (5%) Query: 197 DISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASG-DGD 255 D+SK +++ ++ +NPTG Q E+ + +K +D AY + S D Sbjct: 203 DLSKA-KRTDIIFFCSPNNPTGAAATRAQLTELVNFARKNGSILVYDAAYALYISNPDCP 261 Query: 256 KDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCK 296 K + + E I C S++K G G R+G +TVV K Sbjct: 262 KTIYEIPGADEVAIETC---SFSKYAGFTGVRLG-WTVVPK 298 >1O4S-A nrPDB Length = 389 Score = 34.3 bits (77), Expect = 0.094, Method: Compositional matrix adjust. Identities = 33/155 (21%), Positives = 63/155 (40%), Gaps = 8/155 (5%) Query: 154 DVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKI-PEQSVLLLHAC 212 +V + P W ++ P AG + + K +F +LE++ + ++ +L Sbjct: 127 EVIVFSPVWVSYIPQIILAGGTVNVVETFMSK----NFQPSLEEVEGLLVGKTKAVLINS 182 Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC 272 +NPTGV R E + + + KK+N + D Y D V ++ + Sbjct: 183 PNNPTGVVYRREFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDR---IV 239 Query: 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQ 307 ++K+ + G RVG K A +++S Sbjct: 240 YINGFSKSHSMTGWRVGYLISSEKVATAVSKIQSH 274 >3EI8-A nrPDB Length = 432 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 5/105 (4%) Query: 192 SGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFAS 251 +G D+S + ++ +NPTG EQ ++ KK +D AY + S Sbjct: 187 NGFFPDLSTVGRTDIIFF-CSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMS 245 Query: 252 GDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCK 296 D + + + E + +YA G G R+G +TV+ K Sbjct: 246 DDNPRSIFEIPGAEEVAMETASFSNYA---GFTGVRLG-WTVIPK 286 >4FL0-A nrPDB Length = 456 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 23/93 (24%), Positives = 36/93 (38%), Gaps = 4/93 (4%) Query: 197 DISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDK 256 D++ P V+ +NPTG +Q ++ K FD AY F + Sbjct: 206 DLAMTPRTDVIFF-CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR 264 Query: 257 DAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 + + E I V S++K G G R+G Sbjct: 265 SIYEIPGAREVAIEVS---SFSKFAGFTGVRLG 294 >4CVQ-A nrPDB Length = 431 Score = 32.0 bits (71), Expect = 0.58, Method: Compositional matrix adjust. Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 6/138 (4%) Query: 125 RFVTVQTIS-GTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYD 183 R VTV+ I G G + +Q ++ +P P + P++ A G + Sbjct: 117 RDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDY----PLWTAAVSLSSGKAVHY 172 Query: 184 PKTCGFDFSGALEDI-SKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFF 242 D+ L+DI +KI ++ ++ +NPTG E EI + ++ NL F Sbjct: 173 LCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFA 232 Query: 243 DMAYQGFASGDGDKDAWA 260 D Y D + + A Sbjct: 233 DEIYDKILYDDAEHHSIA 250 >5IX2-A nrPDB Length = 451 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 3/35 (8%) Query: 195 LEDISKIPEQSVLLLHACAH---NPTGVDPRPEQW 226 +EDI K P+Q+ + AC P G+D PE+W Sbjct: 394 VEDIQKRPDQTWVQCDACLKWRKLPDGIDQLPEKW 428 >3GET-A nrPDB Length = 365 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 52/136 (38%), Gaps = 12/136 (8%) Query: 164 NHTPIFRDAGMQLQGYRYYDPKTCGF------DFSGALEDISKIPE---QSVLLLHACA- 213 N F AG+ Y Y K CG + L++ K+ E + L+ C Sbjct: 104 NSKNAFLQAGVTFAMYEIY-AKQCGAKCYKTQSITHNLDEFKKLYETHKDEIKLIFLCLP 162 Query: 214 HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCL 273 +NP G + E V + L D AY FAS K I++ NV Sbjct: 163 NNPLGECLDASEATEFIKGVNEDCLVVI-DAAYNEFASFKDSKKHLEPCELIKEFDNVLY 221 Query: 274 CQSYAKNMGLYGERVG 289 +++K GL G R+G Sbjct: 222 LGTFSKLYGLGGLRIG 237 >3ASB-A nrPDB Length = 400 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 14/134 (10%) Query: 200 KIPEQS-VLLLHACA-HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDG-DK 256 + PE + + +L C+ +NPTG +Q + I + + FD AY F S K Sbjct: 157 EFPEDTHIDILCLCSPNNPTGTVLNKDQLRAIVHYAIEHEILILFDAAYSTFISDPSLPK 216 Query: 257 DAWAV--RHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRP 314 + + F IN S++K +G G R+G +TV+ +E + I Sbjct: 217 SIFEIPDARFCAIEIN-----SFSKPLGFAGIRLG-WTVI---PQELTYADGHFVIQDWE 267 Query: 315 LYSNPPLNGARIAA 328 + + NGA I A Sbjct: 268 RFLSTTFNGASIPA 281 >4NZ0-A nrPDB Length = 460 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 23/40 (57%) Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTI 132 +K YL GGL C A++ L NN ++++G ++T + Sbjct: 282 EKRYLITGGLPSGCAATSMLNTIMNNIIIRAGLYLTYKNF 321 >1VP4-A nrPDB Length = 425 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 9/78 (11%) Query: 169 FRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKE 228 D GM L + K FD +G KI + + + + HNP GV E+ K Sbjct: 162 LEDDGMDLN---VLERKLSEFDKNG------KIKQVKFIYVVSNFHNPAGVTTSLEKRKA 212 Query: 229 IASVVKKKNLFAFFDMAY 246 + + +K +LF D Y Sbjct: 213 LVEIAEKYDLFIVEDDPY 230 >1M4N-A nrPDB Length = 435 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 41/189 (21%), Positives = 72/189 (38%), Gaps = 40/189 (21%) Query: 215 NPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFA----------------SGDGDKDA 258 NP G + + S V+ K + D Y G A + D + + Sbjct: 202 NPLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVLKDRNCDENSEV 261 Query: 259 WAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSN 318 W H + S +K++GL G RVGA + + V + K+ L S+ Sbjct: 262 WQRVHVV---------YSLSKDLGLPGFRVGAIY-----SNDDMVVAAATKMSSFGLVSS 307 Query: 319 PPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQI 378 + + +L+ L K ++ E R+ + +LVS L+K G S + Sbjct: 308 ---QTQHLLSAMLSDKKLTKNYIAENH---KRLKQRQKKLVSGLQKSGIS----CLNGNA 357 Query: 379 GMFCFTGLK 387 G+FC+ ++ Sbjct: 358 GLFCWVDMR 366 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3PD6-B nrPDB 609 e-175 1TAR-A nrPDB 595 e-171 2CST-A nrPDB 565 e-161 5TON-A nrPDB 558 e-159 3II0-A nrPDB 556 e-159 4WD2-A nrPDB 526 e-150 4W5K-A nrPDB 525 e-149 4RKC-A nrPDB 522 e-149 1YAA-A nrPDB 519 e-147 4F5M-A nrPDB 518 e-147 4WB0-B nrPDB 517 e-147 4H51-A nrPDB 516 e-147 3FSL-A nrPDB 507 e-144 6EZL-A nrPDB 506 e-144 3MEB-A nrPDB 489 e-138 4EFF-A nrPDB 488 e-138 1AY8-A nrPDB 456 e-129 3K7Y-A nrPDB 435 e-122 3RQ1-A nrPDB 336 1e-92 4EMY-A nrPDB 290 6e-79 2X5F-A nrPDB 227 8e-60 6F77-B nrPDB 194 6e-50 1V2E-A nrPDB 156 1e-38 4MY5-A nrPDB 143 1e-34 Sequences not found previously or not previously below threshold: 1GC4-A nrPDB 137 9e-33 1GDE-A nrPDB 135 5e-32 6F35-A nrPDB 132 3e-31 1O4S-A nrPDB 131 6e-31 1J32-A nrPDB 124 7e-29 5WMH-A nrPDB 112 2e-25 1XI9-A nrPDB 112 4e-25 3B46-A nrPDB 104 7e-23 2ZC0-A nrPDB 99 3e-21 2O0R-A nrPDB 96 3e-20 2X5D-A nrPDB 95 6e-20 1U08-A nrPDB 94 1e-19 2GB3-A nrPDB 91 1e-18 5YHV-A nrPDB 91 1e-18 2Z61-A nrPDB 91 1e-18 3ELE-A nrPDB 89 3e-18 3PDX-A nrPDB 89 3e-18 2DOU-A nrPDB 87 9e-18 3H14-A nrPDB 87 2e-17 3DYD-A nrPDB 86 2e-17 2ZJG-A nrPDB 86 2e-17 4WP0-A nrPDB 86 3e-17 3FVS-A nrPDB 86 3e-17 1M4N-A nrPDB 82 4e-16 1IAY-A nrPDB 79 3e-15 2O1B-A nrPDB 78 8e-15 1BW0-A nrPDB 78 9e-15 3ASB-A nrPDB 77 1e-14 3EI8-A nrPDB 76 3e-14 4CVQ-A nrPDB 74 1e-13 4FL0-A nrPDB 73 2e-13 3FFH-A nrPDB 73 3e-13 1YIY-A nrPDB 72 3e-13 3OP7-A nrPDB 72 6e-13 2ZYJ-A nrPDB 69 5e-12 1IJI-A nrPDB 69 5e-12 4WBT-A nrPDB 69 6e-12 4IX8-A nrPDB 68 8e-12 3QGU-A nrPDB 68 9e-12 2ZY2-A nrPDB 68 9e-12 3HDO-A nrPDB 67 2e-11 3AV7-A nrPDB 67 2e-11 1X0M-A nrPDB 67 2e-11 3EZS-A nrPDB 67 2e-11 3NRA-A nrPDB 65 5e-11 3TCM-A nrPDB 65 8e-11 3IF2-A nrPDB 64 1e-10 6HNV-A nrPDB 64 2e-10 4GDY-A nrPDB 63 2e-10 1UU1-A nrPDB 63 2e-10 4R2N-A nrPDB 63 3e-10 1VP4-A nrPDB 62 5e-10 2ZY3-A nrPDB 62 6e-10 3CQ5-A nrPDB 61 8e-10 3IHJ-A nrPDB 61 1e-09 3JTX-A nrPDB 61 1e-09 1WST-A nrPDB 60 2e-09 3FDD-A nrPDB 59 3e-09 3DZZ-A nrPDB 59 3e-09 3F6T-A nrPDB 59 3e-09 1D2F-A nrPDB 59 6e-09 3G0T-A nrPDB 57 1e-08 3GET-A nrPDB 57 1e-08 3EUC-A nrPDB 57 1e-08 3LY1-A nrPDB 55 6e-08 4RAE-A nrPDB 54 1e-07 3L8A-A nrPDB 53 2e-07 3FTB-A nrPDB 53 3e-07 3B1C-A nrPDB 52 5e-07 3T32-A nrPDB 52 6e-07 1C7O-A nrPDB 51 1e-06 4DQ6-A nrPDB 50 2e-06 6HNB-A nrPDB 48 7e-06 4M2J-A nrPDB 48 8e-06 5Z0Q-C nrPDB 46 3e-05 3G7Q-A nrPDB 45 4e-05 3FDB-A nrPDB 45 7e-05 1LC8-A nrPDB 45 7e-05 3P1T-A nrPDB 44 1e-04 5DJ3-A nrPDB 44 2e-04 6C3C-A nrPDB 37 0.019 5IWQ-A nrPDB 37 0.023 5HDM-A nrPDB 36 0.037 4JE5-A nrPDB 35 0.056 2Z0F-A nrPDB 34 0.15 5VC2-A nrPDB 34 0.17 5KR5-A nrPDB 33 0.21 3FKD-A nrPDB 33 0.23 2W21-A nrPDB 32 0.43 2J5V-A nrPDB 32 0.45 4RY2-A nrPDB 32 0.68 4E16-A nrPDB 31 1.1 3TBG-A nrPDB 31 1.1 3GJU-A nrPDB 30 1.4 3NCO-A nrPDB 30 1.4 6IO1-A nrPDB 30 1.6 5KR3-A nrPDB 30 1.9 3WKR-A nrPDB 30 1.9 4AR2-A nrPDB 30 2.0 1SEZ-A nrPDB 30 2.0 5TX1-N nrPDB 30 2.7 5KR6-A nrPDB 30 2.8 2BHU-A nrPDB 29 3.1 3ULE-B nrPDB 29 4.7 5I92-A nrPDB 29 5.1 6D8G-A nrPDB 28 5.4 1WU5-A nrPDB 28 9.9 >3PD6-B nrPDB Length = 401 Score = 609 bits (1570), Expect = e-175, Method: Composition-based stats. Identities = 401/401 (100%), Positives = 401/401 (100%) Query: 30 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA 89 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA Sbjct: 1 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA 60 Query: 90 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 149 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF Sbjct: 61 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 120 Query: 150 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL 209 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL Sbjct: 121 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL 180 Query: 210 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 269 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI Sbjct: 181 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 240 Query: 270 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 329 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT Sbjct: 241 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 300 Query: 330 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 389 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE Sbjct: 301 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 360 Query: 390 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK Sbjct: 361 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 401 >1TAR-A nrPDB Length = 401 Score = 595 bits (1535), Expect = e-171, Method: Composition-based stats. Identities = 347/401 (86%), Positives = 378/401 (94%) Query: 30 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA 89 SSWW+HVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVL VRKAEA IAA Sbjct: 1 SSWWSHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLNCVRKAEAMIAA 60 Query: 90 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 149 K +DKEYLPI GLA+F +ASAELALGEN+E KSGR+VTVQ ISGTG+LRVGA+FLQRFF Sbjct: 61 KKMDKEYLPIAGLADFTRASAELALGENSEAFKSGRYVTVQGISGTGSLRVGANFLQRFF 120 Query: 150 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL 209 KFSRDV+LPKPSWGNHTPIFRDAG+QLQ YRYYDPKTC DF+GA+EDISKIPE+S++LL Sbjct: 121 KFSRDVYLPKPSWGNHTPIFRDAGLQLQAYRYYDPKTCSLDFTGAMEDISKIPEKSIILL 180 Query: 210 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 269 HACAHNPTGVDPR EQWKE+ASVVKK+NL A+FDMAYQGFASGD ++DAWA+RHFIEQGI Sbjct: 181 HACAHNPTGVDPRQEQWKELASVVKKRNLLAYFDMAYQGFASGDINRDAWALRHFIEQGI 240 Query: 270 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 329 +V L QSYAKNMGLYGER GAFTV+C+DAEEAKRVESQLKILIRP+YSNPP+NGARIA+ Sbjct: 241 DVVLSQSYAKNMGLYGERAGAFTVICRDAEEAKRVESQLKILIRPMYSNPPMNGARIASL 300 Query: 330 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 389 IL +P+LRK+WL EVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE Sbjct: 301 ILNTPELRKEWLVEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 360 Query: 390 QVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 QVERLTKEFS+YMTKDGRISVAGV S NVGYLAHAIHQVTK Sbjct: 361 QVERLTKEFSIYMTKDGRISVAGVASSNVGYLAHAIHQVTK 401 >2CST-A nrPDB Length = 411 Score = 565 bits (1457), Expect = e-161, Method: Composition-based stats. Identities = 200/407 (49%), Positives = 278/407 (68%), Gaps = 6/407 (1%) Query: 29 ASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIA 88 A+S + V PP + +T F+ D +S+K+NLGVGAYR D G+P+VLP VRK E IA Sbjct: 1 AASIFAAVPRAPPVAVFKLTADFREDGDSRKVNLGVGAYRTDEGQPWVLPVVRKVEQLIA 60 Query: 89 AK-NLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQR 147 +L+ EYLPI GL EF ++ +ALG+++ + R +VQ + GTGALR+GA FL+R Sbjct: 61 GDGSLNHEYLPILGLPEFRANASRIALGDDSPAIAQKRVGSVQGLGGTGALRIGAEFLRR 120 Query: 148 FFKFSR----DVFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALEDISKIP 202 ++ + V++ P+W NH +F DAG + ++ YRY+D G D G L+D+ K P Sbjct: 121 WYNGNNNTATPVYVSSPTWENHNSVFMDAGFKDIRTYRYWDAAKRGLDLQGLLDDMEKAP 180 Query: 203 EQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVR 262 E S+ +LHACAHNPTG DP P++WK+IA+V+K++ LF FFD AYQGFASG DKDAWAVR Sbjct: 181 EFSIFILHACAHNPTGTDPTPDEWKQIAAVMKRRCLFPFFDSAYQGFASGSLDKDAWAVR 240 Query: 263 HFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLN 322 +F+ +G + QS++KN GLY ERVG +VV KD + +RV SQ++ ++R +SNPP Sbjct: 241 YFVSEGFELFCAQSFSKNFGLYNERVGNLSVVGKDEDNVQRVLSQMEKIVRTTWSNPPSQ 300 Query: 323 GARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFC 382 GARI AT LTSP L +W VK MADR++ MR++L S L+ G+ W HITDQIGMF Sbjct: 301 GARIVATTLTSPQLFAEWKDNVKTMADRVLLMRSELRSRLESLGTPGTWNHITDQIGMFS 360 Query: 383 FTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVT 429 FTGL P+QVE + KE +Y+ GRI++ G+T+ N+ Y+A +IH+ Sbjct: 361 FTGLNPKQVEYMIKEKHIYLMASGRINMCGLTTKNLDYVAKSIHEAV 407 >5TON-A nrPDB Length = 414 Score = 558 bits (1438), Expect = e-159, Method: Composition-based stats. Identities = 192/409 (46%), Positives = 270/409 (66%), Gaps = 6/409 (1%) Query: 27 ARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQ 86 S + V P + + F+ D + +K+NLGVGAYR D+ +P+VLP VRK E + Sbjct: 2 MAPPSVFAEVPQAQPVLVFKLIADFREDPDPRKVNLGVGAYRTDDCQPWVLPVVRKVEQR 61 Query: 87 IAAKN-LDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFL 145 IA + L+ EYLPI GLAEF ++ LALG+++ L+ R VQ++ GTGALR+GA FL Sbjct: 62 IANNSSLNHEYLPILGLAEFRTCASRLALGDDSPALQEKRVGGVQSLGGTGALRIGAEFL 121 Query: 146 QRFFKFSR----DVFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALEDISK 200 R++ + V++ P+W N +F AG + ++ YRY+D + G D G L D+ Sbjct: 122 ARWYNGTNNKDTPVYVSSPTWENLNGVFTTAGFKDIRSYRYWDTEKRGLDLQGFLSDLEN 181 Query: 201 IPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWA 260 PE S+ +LHACAHNPTG DP PEQWK+IASV+K++ LF FFD AYQGFASG+ +KDAWA Sbjct: 182 APEFSIFVLHACAHNPTGTDPTPEQWKQIASVMKRRFLFPFFDSAYQGFASGNLEKDAWA 241 Query: 261 VRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPP 320 +R+F+ +G + QS++KN GLY ERVG TVV K+ + RV SQ++ ++R +SNPP Sbjct: 242 IRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVAKEPDSILRVLSQMQKIVRVTWSNPP 301 Query: 321 LNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGM 380 GARI A L+ P+L +W VK MADRI+SMR++L + L+ + W HITDQIGM Sbjct: 302 AQGARIVARTLSDPELFHEWTGNVKTMADRILSMRSELRARLEALKTPGTWNHITDQIGM 361 Query: 381 FCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVT 429 F FTGL P+QVE L + +Y+ GRI++ G+T+ N+ Y+A +IH+ Sbjct: 362 FSFTGLNPKQVEYLINQKHIYLLPSGRINMCGLTTKNLDYVATSIHEAV 410 >3II0-A nrPDB Length = 422 Score = 556 bits (1434), Expect = e-159, Method: Composition-based stats. Identities = 193/396 (48%), Positives = 272/396 (68%), Gaps = 6/396 (1%) Query: 40 PPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN-LDKEYLP 98 P + +T F+ D + +K+NLGVGAYR D+ P+VLP V+K E +IA N L+ EYLP Sbjct: 2 QPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLP 61 Query: 99 IGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSR----D 154 I GLAEF ++ LALG+++ LK R VQ++ GTGALR+GA FL R++ + Sbjct: 62 ILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTP 121 Query: 155 VFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACA 213 V++ P+W NH +F AG + ++ YRY+D + G D G L D+ PE S+++LHACA Sbjct: 122 VYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACA 181 Query: 214 HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCL 273 HNPTG+DP PEQWK+IASV+K + LF FFD AYQGFASG+ ++DAWA+R+F+ +G Sbjct: 182 HNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFC 241 Query: 274 CQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTS 333 QS++KN GLY ERVG TVV K+ E +V SQ++ ++R +SNPP GARI A+ L++ Sbjct: 242 AQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSN 301 Query: 334 PDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVER 393 P+L ++W VK MADRI++MR++L + L+ + W HITDQIGMF FTGL P+QVE Sbjct: 302 PELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEY 361 Query: 394 LTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVT 429 L E +Y+ GRI+V+G+T+ N+ Y+A +IH+ Sbjct: 362 LVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAV 397 >4WD2-A nrPDB Length = 408 Score = 526 bits (1355), Expect = e-150, Method: Composition-based stats. Identities = 170/406 (41%), Positives = 236/406 (58%), Gaps = 2/406 (0%) Query: 25 ASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE 84 A + H++ P DPIL + E F++D +K+NL +G Y D G+ V+ +VR+AE Sbjct: 2 AHHHHHHMFEHIDAYPGDPILTLNENFQKDPRDQKVNLSIGIYFDAEGRIPVMGAVREAE 61 Query: 85 AQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASF 144 + + K YLP+ GLA + A L G ++ +GR T+QT+ G+GAL+VGA F Sbjct: 62 TALQRDSGPKPYLPMVGLAAYRDAVQSLVFGADHPARAAGRIATLQTLGGSGALKVGADF 121 Query: 145 LQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQ 204 L+R+F V+L PSW NH IF AG + Y YYD T G F L I +P + Sbjct: 122 LKRYF-PDSQVWLSDPSWENHRFIFERAGFTVNTYPYYDEATGGLKFDAMLAAIDALPAR 180 Query: 205 SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHF 264 S++LLHAC HNPTGVD QW+++ V++ + L F DMAYQGF +G D DA+AVR Sbjct: 181 SIVLLHACCHNPTGVDLDEGQWEKLIDVIEARELLPFVDMAYQGFGAG-LDADAFAVREL 239 Query: 265 IEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGA 324 +G+ + S++KN LYGERVG +VVC+DA A+RV QL +R YSNP GA Sbjct: 240 ARRGVPTLVANSFSKNFSLYGERVGGLSVVCEDAAAAERVLGQLAGAVRSNYSNPQTYGA 299 Query: 325 RIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFT 384 ++ A +L +P LRKQW +E+ M RI MR + L+ S Q GMF +T Sbjct: 300 KVVAAVLGTPALRKQWEEELSAMCRRIARMRQSIHDGLRDHVSGEALTRYVKQRGMFTYT 359 Query: 385 GLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 GL QV+ L + VY+ + GR+ VAG+ NVG +A AI +V K Sbjct: 360 GLTESQVDALREVHGVYILRSGRMCVAGLNDSNVGIVADAIGKVLK 405 >4W5K-A nrPDB Length = 396 Score = 525 bits (1352), Expect = e-149, Method: Composition-based stats. Identities = 186/393 (47%), Positives = 253/393 (64%), Gaps = 5/393 (1%) Query: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97 MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y Sbjct: 9 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 63 Query: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157 P+ G+A F + + +L G L+ GR + QT+ GTGALR+G L RF ++ Sbjct: 64 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 123 Query: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217 P + NH IF AGM+L Y YYDP T G + +G LE + K PE SV+L+HACAHNPT Sbjct: 124 PDVGYPNHESIFAKAGMELTPYSYYDPATKGLNLAGMLECLDKAPEGSVILVHACAHNPT 183 Query: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277 GVDP + W+++ V+K++N F DMAYQGFA+G D DA+ RH ++ N+ + QS+ Sbjct: 184 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 243 Query: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLR 337 + N GLYG R GA + AEEAKR+ SQL +LIRP+YSNPPL GA + ++IL P L Sbjct: 244 SANFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 303 Query: 338 KQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKE 397 W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E Sbjct: 304 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 363 Query: 398 FSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 + +YMT +GR +V+G+ S NV Y++ AIH VTK Sbjct: 364 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 396 >4RKC-A nrPDB Length = 398 Score = 522 bits (1345), Expect = e-149, Method: Composition-based stats. Identities = 170/399 (42%), Positives = 242/399 (60%), Gaps = 2/399 (0%) Query: 32 WWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN 91 + ++ DPILG+ E F D N K+NLG+G Y D++G VL V+ AE +IA Sbjct: 1 MFERIDYYAGDPILGLVEKFAADNNPDKVNLGIGIYYDESGVMPVLDCVKIAEQRIADPI 60 Query: 92 LDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKF 151 + YLP+ GL K EL G++ VLK G T+ TI G+GAL+VGA F+ +F Sbjct: 61 SPRPYLPMAGLPGHRKGCQELLFGKDAPVLKDGLVATIATIGGSGALKVGAEFIHEWFPQ 120 Query: 152 SRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHA 211 S+ ++ P+WGNH IF +++ Y YYD T G F + + + VLLLH Sbjct: 121 SK-CYVSDPTWGNHIAIFEGCDIEVGKYPYYDTATGGIKFDEMIAFFETLNKDDVLLLHP 179 Query: 212 CAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINV 271 C HNPTGVD EQW + +V++++ L F D+AYQGF D D DA+A+R ++ G+ + Sbjct: 180 CCHNPTGVDLTREQWDTVLNVIQERELIPFMDIAYQGFGE-DMDSDAYAIRKAVDMGLPL 238 Query: 272 CLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATIL 331 + S++KN+ LYGERVG +VVC +E +RV QL +R +YS+PP +G R+ ++ Sbjct: 239 FVSNSFSKNLSLYGERVGGLSVVCPTVDETERVFGQLNSTVRRIYSSPPSHGGRVVDIVM 298 Query: 332 TSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQV 391 L +QW+ EV M DRI SMRT+L S L+ + S N+ ++T Q GMF FTGL PEQV Sbjct: 299 NDAALHEQWVGEVYAMRDRIKSMRTKLKSVLEAKISGRNFDYLTAQNGMFSFTGLTPEQV 358 Query: 392 ERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 ERL EF +YM + R+ VAG+ S N+ Y+A+A+ V K Sbjct: 359 ERLQSEFGIYMISNSRMCVAGLNSSNIDYVANAMVDVLK 397 >1YAA-A nrPDB Length = 412 Score = 519 bits (1336), Expect = e-147, Method: Composition-based stats. Identities = 180/410 (43%), Positives = 260/410 (63%), Gaps = 9/410 (2%) Query: 29 ASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIA 88 +++ + ++E+ PPD + G+ + + +D + K++LG+GAYRDDNGKP+VLPSV+ AE I Sbjct: 1 SATLFNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIH 60 Query: 89 AKN-LDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQR 147 + + EYL I GL +A++ G ++ L+ R ++VQ++SGTGAL + A F + Sbjct: 61 NDSSYNHEYLGITGLPSLTSNAAKIIFGTQSDALQEDRVISVQSLSGTGALHISAKFFSK 120 Query: 148 FFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVL 207 FF + V+L KP+W NH IF + G++ Y Y+ +T D +G L I K PE S+ Sbjct: 121 FF-PDKLVYLSKPTWANHMAIFENQGLKTATYPYWANETKSLDLNGFLNAIQKAPEGSIF 179 Query: 208 LLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQ 267 +LH+CAHNPTG+DP EQW +I + KN A FD AYQGFA+GD DKDA+AVR +E+ Sbjct: 180 VLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVRLGVEK 239 Query: 268 ---GINVCLCQSYAKNMGLYGERVGAFTVV----CKDAEEAKRVESQLKILIRPLYSNPP 320 V +CQS+AKN G+YGERVG F + ++ V SQL +IR SNPP Sbjct: 240 LSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSEVSNPP 299 Query: 321 LNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGM 380 GA+I A +L +P+L +QW +++ M+ RI MR L +L K G+ NW HI +Q GM Sbjct: 300 AYGAKIVAKLLETPELTEQWHKDMVTMSSRITKMRHALRDHLVKLGTPGNWDHIVNQCGM 359 Query: 381 FCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 F FTGL P+ V+RL + +VY+ GR S+AG+ GNV Y+A AI +V + Sbjct: 360 FSFTGLTPQMVKRLEETHAVYLVASGRASIAGLNQGNVEYVAKAIDEVVR 409 >4F5M-A nrPDB Length = 406 Score = 518 bits (1335), Expect = e-147, Method: Composition-based stats. Identities = 166/397 (41%), Positives = 233/397 (58%), Gaps = 2/397 (0%) Query: 33 WTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNL 92 + ++ P DPILG+ + F+ D K+NLG+G Y+D+ GK VL SV+KAE + Sbjct: 12 FENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLENET 71 Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 K YL I G+ EF + + EL G+ + ++ R T QT GTGALRV A FL + Sbjct: 72 TKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKNTS-V 130 Query: 153 RDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHAC 212 + V++ PSW NH +F AG++++ Y YYD + DF + +++ V+L H C Sbjct: 131 KRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFDALINSLNEAQAGDVVLFHGC 190 Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC 272 HNPTG+DP EQW+ +A + +K FD AYQGFA G ++DA +R F + Sbjct: 191 CHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARG-LEEDAEGLRAFAAMHKELI 249 Query: 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILT 332 + SY+KN GLY ERVGA T+V D+E R SQ+K IR YSNPP +GA + ATIL+ Sbjct: 250 VASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNPPAHGASVVATILS 309 Query: 333 SPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVE 392 + LR W QE+ M RI MR V+ L+++G++ ++ I Q GMF F+GL EQV Sbjct: 310 NDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKEQVL 369 Query: 393 RLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVT 429 RL +EF VY GR++VAG+T N+ L AI V Sbjct: 370 RLREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAVL 406 >4WB0-B nrPDB Length = 414 Score = 517 bits (1332), Expect = e-147, Method: Composition-based stats. Identities = 173/413 (41%), Positives = 241/413 (58%), Gaps = 7/413 (1%) Query: 20 GLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPS 79 ++ A+ + W ++ PDPI + + K NL +GAYRD+ G PY L Sbjct: 2 HMSTQAAMTTTERWQKIQGRAPDPIFELAKRAAAAKGP-KANLVIGAYRDEQGLPYPLRV 60 Query: 80 VRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALR 139 VRKAE + NL+ EYLPI G F + ++ G+ E+ V VQT+SGTGAL Sbjct: 61 VRKAEQLLLDMNLNYEYLPISGYQPFIDEAVKMTYGDTVEL---ENLVAVQTLSGTGALS 117 Query: 140 VGASFLQRFFK-FSRDVFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALED 197 +GA L F ++L P+W NH I + AG + ++ Y YYD KT G DF G +D Sbjct: 118 LGAKLLTHVFDAEKTPIYLADPTWPNHYSIVKAAGWKDIRTYAYYDHKTLGLDFEGMKKD 177 Query: 198 ISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKD 257 I P+ SV LLH CAHNPTGVDP EQW EIAS++ K+ FFD AYQG+ASG D D Sbjct: 178 ILAAPDGSVFLLHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTD 237 Query: 258 AWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYS 317 A+A R F +GI V L QS++KNMGLY ER G +++ KD + V+S + LIR Y+ Sbjct: 238 AYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDSLIRAEYT 297 Query: 318 NPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQ 377 PP +GAR+A IL++ +LRK+W E+ MA+RI +MR + L + + W+H+ +Q Sbjct: 298 CPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQTPGRWEHVINQ 357 Query: 378 IGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 IGMF F GL EQ E + ++++T GR ++AG+T LA I+ + Sbjct: 358 IGMFSFLGLSKEQCEY-CQNHNIFITLSGRANIAGLTHETALMLAQTINDAVR 409 >4H51-A nrPDB Length = 420 Score = 516 bits (1328), Expect = e-147, Method: Composition-based stats. Identities = 172/420 (40%), Positives = 243/420 (57%), Gaps = 7/420 (1%) Query: 13 MAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNG 72 MA H ++ A+ + W ++ PD I + + K NL +GAYRD+ G Sbjct: 1 MAHHHHHHMSTQAAMTTAERWQKIQAQAPDVIFDLAKRAAAAKGP-KANLVIGAYRDEQG 59 Query: 73 KPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTI 132 +PY L VRKAE + NLD EYLPI G F + ++ G E+ V VQT+ Sbjct: 60 RPYPLRVVRKAEQLLLDMNLDYEYLPISGYQPFIDEAVKIIYGNTVEL---ENLVAVQTL 116 Query: 133 SGTGALRVGASFLQRFFK-FSRDVFLPKPSWGNHTPIFRDAGM-QLQGYRYYDPKTCGFD 190 SGTGA+ +GA L R F + ++L P+W NH + + AG + Y YYDPKT + Sbjct: 117 SGTGAVSLGAKLLTRVFDAETTPIYLSDPTWPNHYGVVKAAGWKNICTYAYYDPKTVSLN 176 Query: 191 FSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFA 250 F G +DI P+ SV +LH CAHNPTGVDP EQW EIAS++ K+ FFD AYQG+A Sbjct: 177 FEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYA 236 Query: 251 SGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKI 310 SG D DA+A R F +GI V L QS++KNMGLY ER G +++ KD + V+S + Sbjct: 237 SGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDS 296 Query: 311 LIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHN 370 LIR Y+ PP +GAR+A IL++ +LRK+W E+ MA+RI +MR + L + + + Sbjct: 297 LIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQTPGS 356 Query: 371 WQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 W+H+ +QIGMF F GL Q E + ++++T GR ++AG+T LA I+ + Sbjct: 357 WEHVINQIGMFSFLGLSKAQCEY-CQNHNIFITVSGRANMAGLTHETALMLAQTINDAVR 415 >3FSL-A nrPDB Length = 397 Score = 507 bits (1306), Expect = e-144, Method: Composition-based stats. Identities = 163/399 (40%), Positives = 238/399 (59%), Gaps = 3/399 (0%) Query: 32 WWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN 91 + V+ DPIL + E FK D S K+NL +G Y +++G L +V +AEA++ A+ Sbjct: 1 MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQP 60 Query: 92 LDKE-YLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFK 150 YLP+ GL + A A L G ++ VLK R T+QT+ G+GAL+VGA FL+R+F Sbjct: 61 HGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFP 120 Query: 151 FSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLH 210 S V++ P+W NH IF AG ++ Y +YD T G F+ L + + S++LLH Sbjct: 121 ES-GVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLATLKTLQAGSIVLLH 179 Query: 211 ACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN 270 C HNPTG D +QW + ++K + L F D+AYQGF +G ++DA+A+R G+ Sbjct: 180 PCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAG-MEEDAYAIRAIASAGLP 238 Query: 271 VCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATI 330 + S++K LYGERVG +V+C+DAE A RV QLK +R YS+PP GA++ A + Sbjct: 239 ALVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAV 298 Query: 331 LTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQ 390 L L+ WL+EV+ M RI++MR +LV L E N+ ++ +Q GMF +TGL Q Sbjct: 299 LNDEALKASWLKEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQ 358 Query: 391 VERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVT 429 V+RL +EF VY+ GR+ VAG+ + NV +A A V Sbjct: 359 VDRLREEFGVYLIASGRMCVAGLNTANVQRVAKAFAAVM 397 >6EZL-A nrPDB Length = 404 Score = 506 bits (1304), Expect = e-144, Method: Composition-based stats. Identities = 168/400 (42%), Positives = 245/400 (61%), Gaps = 6/400 (1%) Query: 32 WWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN 91 W ++ P DPI + K+ K +L +GAYRD G PY L VRKAE ++ N Sbjct: 6 LWNNIAALPADPIFSASLVAKKAPEP-KADLIIGAYRDAEGHPYPLNVVRKAEQRLLEMN 64 Query: 92 LDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKF 151 DKEYLP+ G A F + S ++A G++ + V +Q +SGTG+L +GA FL R Sbjct: 65 ADKEYLPMSGYAPFIEESLKIAYGDS---VARENVVGIQGLSGTGSLSIGACFLARVLSR 121 Query: 152 SRDVFLPKPSWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLH 210 V++ P+W NH + A + L+ YRYYD DF G LED++ PE S+++LH Sbjct: 122 DTPVYISDPTWPNHYAVMAAANLTDLRKYRYYDNAKRCIDFDGLLEDLNGAPEGSIVILH 181 Query: 211 ACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGIN 270 ACAHNPTG+DP EQW +I V + + L FFD AYQG+A+G D DA+++R F QG+ Sbjct: 182 ACAHNPTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGME 241 Query: 271 VCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATI 330 + L QSY+KNMGLY ERVG ++V + ++A ++SQL+ ++R YS PP +GAR+A + Sbjct: 242 MLLAQSYSKNMGLYAERVGVCSIVTANPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLV 301 Query: 331 LTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQ 390 L+ P+LR W QE++ M+ R++ MR L LK+ G+ +W+HI Q+GMF + GL Q Sbjct: 302 LSDPELRAGWEQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGLTKAQ 361 Query: 391 VERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 E+L E V++ GR ++AG+T +V L I +V + Sbjct: 362 CEKLI-ERRVFVLPSGRANMAGLTKRSVELLVKGIDEVVR 400 >3MEB-A nrPDB Length = 448 Score = 489 bits (1258), Expect = e-138, Method: Composition-based stats. Identities = 167/442 (37%), Positives = 252/442 (57%), Gaps = 26/442 (5%) Query: 13 MAAAFHPGLAAAASAR----ASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYR 68 MA H + + + S ++ PPD IL +T + DTN KK+NLGVGAYR Sbjct: 1 MAHHHHHHMGTLEAQTQGPGSMSVFSGFPASPPDAILNLTVLYNADTNPKKVNLGVGAYR 60 Query: 69 DDNGKPYVLPSVRKAEAQIAAK--NLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRF 126 D++GKP++LP+V++AEA I++ +KEY P+ G F +A+ L G++++ + GR Sbjct: 61 DESGKPWILPAVKEAEAIISSDLSKYNKEYPPVAGFPLFLEAAQFLMFGKDSKAAQEGRI 120 Query: 127 VTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQ-GYRYY--- 182 + Q++SGTG+L +G FL + + ++P +W NH I+ +L+ Y+ Y Sbjct: 121 ASCQSLSGTGSLHIGFEFLHLWM-PKAEFYMPSTTWPNHYGIYDKVFNKLKVPYKEYTYL 179 Query: 183 -DPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAF 241 DFS +DI PE+S+ L HACAHNP+G+D QWKE+ ++K+K AF Sbjct: 180 RKDGELEIDFSNTKKDIQSAPEKSIFLFHACAHNPSGIDFTEAQWKELLPIMKEKKHIAF 239 Query: 242 FDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVC------ 295 FD AYQGFA+G + DA+AVR F++ G+ V + QS++KN GLYGER+G VV Sbjct: 240 FDSAYQGFATGSFEADAFAVRMFVDAGVEVLVAQSFSKNFGLYGERIGCLHVVHAGVEGS 299 Query: 296 --KDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIIS 353 K+ + + S + + IR +S ++GA I I+ L + + VK M+ RI Sbjct: 300 VEKNKALSAAMVSGMTLQIRKTWSMSAIHGAYIVQVIVHDKRLLQMFYDNVKEMSARIHR 359 Query: 354 MRTQLVSNLKKEGSS-----HNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTK-DGR 407 MR+ L ++L K + W HI IGMF FTGL PE V+ L +++S+Y+ K GR Sbjct: 360 MRSLLHASLAKRKTPGPGSKGTWDHILTAIGMFTFTGLTPEHVDYLKEKWSIYLVKAGGR 419 Query: 408 ISVAGVTSGNVGYLAHAIHQVT 429 +S+ G+T N Y+A AIH Sbjct: 420 MSMCGLTESNCDYVAEAIHDAV 441 >4EFF-A nrPDB Length = 420 Score = 488 bits (1255), Expect = e-138, Method: Composition-based stats. Identities = 179/422 (42%), Positives = 250/422 (59%), Gaps = 6/422 (1%) Query: 13 MAAAFHPGLAAAASAR----ASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYR 68 MA H + + + S ++ VE+ P DPILG+ EAF DT K+NLGVG Y Sbjct: 1 MAHHHHHHMGTLEAQTQGPGSMSLFSAVELAPRDPILGLNEAFNADTRPTKVNLGVGVYT 60 Query: 69 DDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVT 128 +++GK +L +VR AE L + YLPI G+A + + +L LG+++ ++ +GR VT Sbjct: 61 NEDGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDASVQKLLLGDDSPLIAAGRVVT 120 Query: 129 VQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCG 188 Q + GTGAL++GA FL R V + PSW NH +F AG ++ Y YYD KT G Sbjct: 121 AQALGGTGALKIGADFL-RTLNPKAKVAISDPSWENHRALFDMAGFEVVAYPYYDAKTNG 179 Query: 189 FDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQG 248 +F G L ++ ++++LHAC HNPTGVD QW ++ VVK + L F D+AYQG Sbjct: 180 VNFDGMLAALNGYEPGTIVVLHACCHNPTGVDLNDAQWAQVVEVVKARRLVPFLDIAYQG 239 Query: 249 FASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQL 308 F + DA AVR F +NV + S++K+ LYGERVGA +++ +EA RV SQL Sbjct: 240 FGE-SIEADAAAVRLFAAANLNVFVSSSFSKSFSLYGERVGALSIITDSKDEAARVLSQL 298 Query: 309 KILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSS 368 K +IR YSNPP +G I A +L SP+LR W+QE+ M DRI +MR LV LK G Sbjct: 299 KRVIRTNYSNPPTHGGAIVAAVLASPELRASWVQELGEMRDRIRAMRNGLVERLKAAGIE 358 Query: 369 HNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQV 428 ++ I Q GMF ++GL QV+RL +EF +Y GRI VA + + N+ +A+AI V Sbjct: 359 RDFSFINAQRGMFSYSGLTSAQVDRLREEFGIYAVSTGRICVAALNTRNLDVVANAIAAV 418 Query: 429 TK 430 K Sbjct: 419 LK 420 >1AY8-A nrPDB Length = 394 Score = 456 bits (1173), Expect = e-129, Method: Composition-based stats. Identities = 143/394 (36%), Positives = 213/394 (54%), Gaps = 5/394 (1%) Query: 35 HVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDK 94 +++ PD IL + F+ D K++LGVG Y+D G ++ +V AE ++ K Sbjct: 4 NLKPQAPDKILALMGEFRADPRQGKIDLGVGVYKDATGHTPIMRAVHAAEQRMLETETTK 63 Query: 95 EYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRD 154 Y + G EF KA EL LG+ LKS T+ T+ GTGALR L R Sbjct: 64 TYAGLSGEPEFQKAMGELILGDG---LKSETTATLATVGGTGALRQALE-LARMANPDLR 119 Query: 155 VFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAH 214 VF+ P+W NH I G+ +Q YRY+D +T G DF G D++ + ++LLH C H Sbjct: 120 VFVSDPTWPNHVSIMNFMGLPVQTYRYFDAETRGVDFEGMKADLAAAKKGDMVLLHGCCH 179 Query: 215 NPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLC 274 NPTG + +QW EIAS+++K D+AYQGF G ++DA R + V + Sbjct: 180 NPTGANLTLDQWAEIASILEKTGALPLIDLAYQGFGDG-LEEDAAGTRLIASRIPEVLIA 238 Query: 275 QSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSP 334 S +KN G+Y ER G +C DA + + + L R YS PP +GA+I +T+LT+P Sbjct: 239 ASCSKNFGIYRERTGCLLALCADAATRELAQGAMAFLNRQTYSFPPFHGAKIVSTVLTTP 298 Query: 335 DLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERL 394 +LR W+ E++ + ++ +R QL L+ S + + + GMF G PEQV+R+ Sbjct: 299 ELRADWMAELEAVRSGMLRLREQLAGELRDLSGSDRFGFVAEHRGMFSRLGATPEQVKRI 358 Query: 395 TKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQV 428 +EF +YM D RI++AG+ + LA AI +V Sbjct: 359 KEEFGIYMVGDSRINIAGLNDNTIPILARAIIEV 392 >3K7Y-A nrPDB Length = 405 Score = 435 bits (1119), Expect = e-122, Method: Composition-based stats. Identities = 124/398 (31%), Positives = 204/398 (51%), Gaps = 7/398 (1%) Query: 32 WWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKN 91 + +E D IL FK DT +K+NL +G +D+G ++ SV A+ + Sbjct: 4 LLSSLENIEVDNILKTAREFKEDTCEEKINLSIGVCCNDDGDLHIFDSVLNADKLVTENY 63 Query: 92 LDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKF 151 +K YL G +F + L G N++ ++ + T+Q I GTGA+ V FL+ Sbjct: 64 KEKPYLLGNGTEDFSTLTQNLIFGNNSKYIEDKKICTIQCIGGTGAIFVLLEFLKML--N 121 Query: 152 SRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHA 211 +++ P + NH + G L+ ++D ++ L D+ IP S ++L Sbjct: 122 VETLYVTNPPYINHVNMIESRGFNLKYINFFDYNLIDINYDLFLNDLRNIPNGSSVILQI 181 Query: 212 CAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINV 271 +NP V+ + + EI +V K FD+AYQGF + ++D +R F E+ I Sbjct: 182 SCYNPCSVNIEEKYFDEIIEIVLHKKHVIIFDIAYQGFGHTNLEEDVLLIRKFEEKNIAF 241 Query: 272 CLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATIL 331 +CQS++KNM LYGER GA +VCK+ EE K V + L ++R YS+P ++ RI +L Sbjct: 242 SVCQSFSKNMSLYGERAGALHIVCKNQEEKKIVFNNLCFIVRKFYSSPVIHTNRILCQLL 301 Query: 332 TSPDLRKQWLQEVKGMADRIISMRTQLVSNL----KKEGSSHNWQHITDQIGMFCFTGLK 387 + +L+ W++E+ ++ RI + R + L KK +++W Q G+F F L Sbjct: 302 NNQNLKLNWIKELSQLSQRITNNRILFFNKLETYQKKYNLNYDWNVYKKQRGLFSFVPLL 361 Query: 388 PEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAI 425 + E L K +Y+ +GRI+V+G+T NV Y+A I Sbjct: 362 AKIAEHL-KTHHIYIINNGRINVSGITKNNVDYIADKI 398 >3RQ1-A nrPDB Length = 418 Score = 336 bits (862), Expect = 1e-92, Method: Composition-based stats. Identities = 92/411 (22%), Positives = 154/411 (37%), Gaps = 38/411 (9%) Query: 42 DPILGVT----EAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97 D I K + +N +GA D+ G L +V++ ++ Y Sbjct: 19 DVIFVTAGQAQADAKENGRENVVNGTLGAIHDEEGNLVFLKTVKEEYLSLSDSEH-VGYA 77 Query: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157 PI G+ +F A+ + G G ++ T GTG + + + + +V Sbjct: 78 PIAGIPDFLCAAEKECFGN---FRPEGHIRSIATAGGTGGIH---HLIHNYTEPGDEVLT 131 Query: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTC--GFDFSGALEDISKIPEQSVLLLHACAHN 215 WG + I D G L Y +D F + +++ V++ + +N Sbjct: 132 ADWYWGAYRVICSDTGRTLVTYSLFDEHNNFNHEAFQNRVNELAAKQTNVVVIFNTPGNN 191 Query: 216 PTGVDPRPEQWKEIASVVK------KKNLFAFFDMAYQGFASGDGDKDAWAVRHFI---- 265 PTG + W I + +K + N+ D+AY + G+KD VR F Sbjct: 192 PTGYSIEDKDWDSILNFLKDLVAIGRNNVIIGIDVAYLDY---SGEKDE--VRAFFNKFS 246 Query: 266 --EQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNG 323 + I C+C S +K +YG+RVGA + D E A K R +SN Sbjct: 247 HLPKEILTCVCYSLSKGFTMYGQRVGAMIGISDDEEIADEFFEVNKSTSRATWSNICRPA 306 Query: 324 ARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCF 383 R A I+ P K++ E + ++I R + K+E + + + G F Sbjct: 307 MRTMANIVADPAKFKEYEAE-RNCYYQLIRDRADI---FKQEAAQVGLPMLPYRGGFFIT 362 Query: 384 --TGLKPEQVERLTKEF--SVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 T E L KE + + RI+ G+ + LA I+ K Sbjct: 363 IPTDSANAICEELKKEHIYVIALANGIRIAACGIPKCQMTGLAEKIYNAMK 413 >4EMY-A nrPDB Length = 413 Score = 290 bits (743), Expect = 6e-79, Method: Composition-based stats. Identities = 91/407 (22%), Positives = 160/407 (39%), Gaps = 37/407 (9%) Query: 41 PDPILGVTEAFKRD----TNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEY 96 PD + +N +G DD GK LPSV ++ ++ Y Sbjct: 17 PDLAFDINNKANAAIEKYGREAVINAALGTLLDDKGKIIALPSVYDRLDEMDRSHI-ASY 75 Query: 97 LPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVF 156 PI G ++ K + G G + T GTGA+R S + + + Sbjct: 76 APIEGEKDYRKIVIDTLFGPYKP---EGYISAIATPGGTGAIR---SAIFSYLDEGDPLI 129 Query: 157 LPKPSWGNHTPIFRDAGMQLQGYRYY-DPKTCGFD-FSGALEDISKIPEQSVLLLHACAH 214 W + I + G + + ++ D D + A+++ + ++ L+++ + Sbjct: 130 CHDYYWAPYRKICEEFGRNFKTFEFFTDDFAFNIDVYKEAIDEGIRDSDRIASLINSPGN 189 Query: 215 NPTGVDPRPEQWKEIASVVKKKN------LFAFFDMAYQGFASGDGDKDAWAVRHF--IE 266 NPTG E+W E+ + +K+K + D+AY FA GDGD+ F + Sbjct: 190 NPTGYSLSDEEWDEVITFLKEKAEDKDKKITLIVDVAYLEFA-GDGDQQRKFFEKFSNLP 248 Query: 267 QGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARI 326 + + V + S +K+ YG R GA + E + E+ L R +SN G Sbjct: 249 RNLFVVVAFSMSKSHTAYGLRSGAAVGISSSKEIIEEFEASLAHSARCNWSN----GTHA 304 Query: 327 AATILTS---PDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCF 383 A IL + +K + QE+ + + + S V+ K+ + I G F F Sbjct: 305 AQNILIELERAENKKIYEQELVDLRNMLKSRADVFVTAAKE----NKLTMIPYFGGFFTF 360 Query: 384 --TGLKPEQVERLTKE--FSVYMTKDGRISVAGVTSGNVGYLAHAIH 426 T + V+ L KE F++ K R+++ GV + L + Sbjct: 361 IPTDKAFDIVKDLEKENIFTIPSAKGIRVAICGVGEEKIPKLVQRLA 407 >2X5F-A nrPDB Length = 430 Score = 227 bits (578), Expect = 8e-60, Method: Composition-based stats. Identities = 88/426 (20%), Positives = 160/426 (37%), Gaps = 35/426 (8%) Query: 24 AASARASSWWTHV--EMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVR 81 ++A A + + + M P IL + K T N +G + +GK + S Sbjct: 16 QSNATAFAMLSDLGQNMFYPKGILSQSAEAKSTT----YNATIGMATNKDGKMFA--SSL 69 Query: 82 KAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVG 141 A + Y P G+ E + L +N E+ + T AL G Sbjct: 70 DAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSRPIV----TNALTHG 125 Query: 142 ASFLQRFF-KFSRDVFLPKPSWGNHTPIFR-DAGMQLQGYRYYDPKTCGFDFSGALEDIS 199 S + F + LP+ +WGN+ +F G LQ Y +D K + +E + Sbjct: 126 LSLVGDLFVNQDDTILLPEHNWGNYKLVFNTRNGANLQTYPIFD-KDGHYTTDSLVEALQ 184 Query: 200 KIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKK-----KNLFAFFDMAYQGFASGDG 254 + V+++ +NPTG P ++ I +K + A D AY G D Sbjct: 185 SYNKDKVIMILNYPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYYGLFYEDV 244 Query: 255 DKDAW--AVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILI 312 + A+ + I K +G RVG T D + +E+++K LI Sbjct: 245 YTQSLFTALTNLHSNAILPIRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEAKVKGLI 304 Query: 313 RPLYSNPPLNGARIAATIL-TSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNW 371 R S+ PL +L + K+ Q ++ + +R + + ++ +W Sbjct: 305 RSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYAD----QYHSHW 360 Query: 372 QHITDQIGMFCFT---GLKPEQV-ERLTKEFSVYMTK----DGRISVAGVTSGNVGYLAH 423 Q G F + PE + + L ++S+ + D RI+ + V ++ ++ Sbjct: 361 QAYDFNSGYFMAIKVHDVDPEALRKHLIDKYSIGVIALNATDIRIAFSCVEKDDIPHVFD 420 Query: 424 AIHQVT 429 +I + Sbjct: 421 SIAKAI 426 >6F77-B nrPDB Length = 400 Score = 194 bits (493), Expect = 6e-50, Method: Composition-based stats. Identities = 69/383 (18%), Positives = 129/383 (33%), Gaps = 32/383 (8%) Query: 34 THVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLD 93 + P + V++ + + +G+GA D P +++KA A A + Sbjct: 6 DALSRVKPSATIAVSQKARELKAKGRDVIGLGAGEPDFDTP---DNIKKA-AIDAIDRGE 61 Query: 94 KEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSR 153 +Y P+ G+ E +A A+ ENN + QTI GTG ++ + Sbjct: 62 TKYTPVSGIPELREAIAKKFKRENNL-----DYTAAQTIVGTGGKQILFNAFMATLNPGD 116 Query: 154 DVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKI-PEQSVLLLHAC 212 +V +P P W ++ + G G + P +F ED+ + ++ + Sbjct: 117 EVVIPAPYWVSYPEMVALCG----GTPVFVPTRQENNFKLKAEDLDRAITPKTKWFVFNS 172 Query: 213 AHNPTGVDPRPEQWKEIASV-VKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINV 271 NP+G E+ K + V +K +++ D Y+ GD + A V Sbjct: 173 PSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDF-RFATPVEVEPGLYERT 231 Query: 272 CLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATIL 331 +K + G R+G + ++ Q S A L Sbjct: 232 LTMNGVSKAYAMTGWRIGYAAGPLHLIKAMDMIQGQQT-------SGAASIAQWAAVEAL 284 Query: 332 TSPDLRKQWLQEV-KGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQ 390 P +E+ +G D ++SM Q + + G+ T + Sbjct: 285 NGPQDFIGRNKEIFQGRRDLVVSMLNQ-AKGISCPTPEGAFYVYPSCAGLIGKTAPSGKV 343 Query: 391 VE-------RLTKEFSVYMTKDG 406 +E L + V + Sbjct: 344 IETDEDFVSELLETEGVAVVHGS 366 >1V2E-A nrPDB Length = 381 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 71/357 (19%), Positives = 121/357 (33%), Gaps = 50/357 (14%) Query: 55 TNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKA-SAELA 113 +NLG G + + P++L +VR+A + +Y P GL +A + E A Sbjct: 23 QRLGAVNLGQG-FPSNPPPPFLLEAVRRALGR------QDQYAPPAGLPALREALAEEFA 75 Query: 114 LGENNEVLKSGR----FVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIF 169 + + V+ SG +V +Q++ G G V L+ FF DV+LP Sbjct: 76 VEPESVVVTSGATEALYVLLQSLVGPGDEVV---VLEPFF----DVYLPDAFLAGAKARL 128 Query: 170 RDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEI 229 + +G+R D S + + ++ LL NPTG+ + + I Sbjct: 129 VRLDLTPEGFR--------LDLSALEKAL---TPRTRALLLNTPMNPTGLVFGERELEAI 177 Query: 230 ASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 A + + +LF D Y G+ + +R F + S K + G RVG Sbjct: 178 ARLARAHDLFLISDEVYDELYYGERPRR---LREFAPE--RTFTVGSAGKRLEATGYRVG 232 Query: 290 AFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMAD 349 K +L + + + P A L + + + Sbjct: 233 WIVG-------PKEFMPRLAGMRQWTSFSAPTPLQAGVAEALKLARREGFYEA----LRE 281 Query: 350 RIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDG 406 R L L+ G + + F L RL +E V + Sbjct: 282 GYRRRRDLLAGGLRAMG----LRVYVPEGTYFLMAELPGWDAFRLVEEARVALIPAS 334 >4MY5-A nrPDB Length = 393 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 77/385 (20%), Positives = 134/385 (34%), Gaps = 45/385 (11%) Query: 57 SKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGL-------AEFCKAS 109 + L +G D P +++A + A + Y + GL + F K Sbjct: 32 PDVLKLTLG--EPDFATP---KHIKEAAKR-AIDADESHYTGMAGLLALRQAASAFVKEK 85 Query: 110 AELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIF 169 L +NE+L TI T AL ++ L + V LP P++ + P+ Sbjct: 86 YHLTYNPDNEIL--------VTIGATEAL---SASLTAILEPGDKVLLPAPAYPGYEPVV 134 Query: 170 RDAGMQLQGYRYYDPKTCGFDFSGAL--EDISKIPEQSVLLLHACAHNPTGVDPRPEQWK 227 G ++ D ++ F + + E I K E ++ NPTGV +Q K Sbjct: 135 NLVGAEVVEI---DTRSNDFVLTPEMLEEAILKEGEALKAVILNYPTNPTGVTYSRQQIK 191 Query: 228 EIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGER 287 +A V+KK +F D Y G+ + +Q L +K+ + G R Sbjct: 192 NLAEVLKKYPIFVISDEVYAELTY-TGESHVSIAEYLPDQ---TILISGLSKSHAMTGWR 247 Query: 288 VGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGM 347 +G + A+ ++S ++ S + A I A D + +K Sbjct: 248 LG--LIFAPAVLTAQLIKSHQYLVTAATTS---VQFAAIEALTNGKDDALPMKEEYIKRR 302 Query: 348 ADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGR 407 I M +K +G+ + + I G F + ++ KE +V Sbjct: 303 DYIIEKMEAMKFKIIKPDGAFYIFAKIPVAQGQDSF-----KFLQDFAKEKAVAFIPGVA 357 Query: 408 ISVAGVTSGNVGYLA--HAIHQVTK 430 G + Y A I + K Sbjct: 358 FGKYGEGYLRISYAASMETIKEAMK 382 >1GC4-A nrPDB Length = 385 Score = 137 bits (345), Expect = 9e-33, Method: Composition-based stats. Identities = 59/333 (17%), Positives = 111/333 (33%), Gaps = 27/333 (8%) Query: 36 VEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKE 95 V+ PD ++ V + + A D P V++A A+ A + Sbjct: 8 VQAMKPDAVVAVNAKALELRRQGVDLVALTAGEPDFDTP---EHVKEA-ARRALAQGKTK 63 Query: 96 YLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDV 155 Y P G+ E +A AE EN + T+ T+ G+ AL + Q +V Sbjct: 64 YAPPAGIPELREALAEKFRRENGLSVTPEE--TIVTVGGSQAL---FNLFQAILDPGDEV 118 Query: 156 FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHN 215 + P W ++ + R AG + + D I ++ L+ +N Sbjct: 119 IVLSPYWVSYPEMVRFAGGVVVEVETLPEEGFVPDPERVRRAI---TPRTKALVVNSPNN 175 Query: 216 PTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQ 275 PTG E + +A + + + + D Y+ + + ++ + Sbjct: 176 PTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLY---EGEHFSPGRVAPEH--TLTVN 230 Query: 276 SYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPD 335 AK + G R+G K V + + R ++P LT+ + Sbjct: 231 GAAKAFAMTGWRIGYACG-------PKEVIKAMASVSRQSTTSPDTIAQWATLEALTNQE 283 Query: 336 LRKQWLQEVKGMADRIISMRTQLVSNLKKEGSS 368 + + V+ + R L+ L G Sbjct: 284 ASRAF---VEMAREAYRRRRDLLLEGLTALGLK 313 >1GDE-A nrPDB Length = 389 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 69/360 (19%), Positives = 122/360 (33%), Gaps = 34/360 (9%) Query: 59 KMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENN 118 K + +G D P + K A+ A Y P GL E +A AE + N Sbjct: 26 KDVISLGIGEPDFDTPQHI----KEYAKEALDKGLTHYGPNIGLLELREAIAEKLK-KQN 80 Query: 119 EVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQG 178 + + + + A +G L F K +V +P P++ ++ P AG + Sbjct: 81 GIEADPKTEIMVLLGANQAFLMG---LSAFLKDGEEVLIPTPAFVSYAPAVILAGGKPVE 137 Query: 179 YRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNL 238 Y+ + + + + L++++ NPTG + +EIA V + +L Sbjct: 138 VPTYEEDEFRLNVDELKKYV--TDKTRALIINSPC-NPTGAVLTKKDLEEIADFVVEHDL 194 Query: 239 FAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDA 298 D Y+ F D +++ ++K + G R+G V Sbjct: 195 IVISDEVYEHFIYD--DARHYSIASLDGMFERTITVNGFSKTFAMTGWRLGF--VAAPSW 250 Query: 299 EEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQL 358 + V+ Q+ + P AA L W V+ M R + Sbjct: 251 IIERMVKFQM-----YNATCPVTFIQYAAAKALKDER---SWKA-VEEMRKEYDRRRKLV 301 Query: 359 VSNLKKEGSSHNWQHITDQIGMFCF-----TGLKPEQ-VERLTKEFSVYMTKDGRISVAG 412 L + G + + + F TGL ++ E + KE V + AG Sbjct: 302 WKRLNEMGLPT----VKPKGAFYIFPRIRDTGLTSKKFSELMLKEARVAVVPGSAFGKAG 357 >6F35-A nrPDB Length = 410 Score = 132 bits (332), Expect = 3e-31, Method: Composition-based stats. Identities = 56/354 (15%), Positives = 108/354 (30%), Gaps = 32/354 (9%) Query: 34 THVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLD 93 + + IL + K + +GA D P V++A A A + Sbjct: 16 SRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTP---EHVKQA-ASDAIHRGE 71 Query: 94 KEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSR 153 +Y + G E KA E EN + TGA ++ + + Sbjct: 72 TKYTALDGTPELKKAIREKFQRENGLAYELDEIT-----VATGAKQILFNAMMASLDPGD 126 Query: 154 DVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKI-PEQSVLLLHAC 212 +V +P P W +++ I +G F E + ++ +L Sbjct: 127 EVIIPTPYWTSYSDIVHIC----EGKPVLIACDASSGFRLTAEKLEAAITPRTRWVLLNS 182 Query: 213 AHNPTGVDPRPEQWKEIASV-VKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINV 271 NP+G ++ + V ++ +++ D Y+ DG + + Sbjct: 183 PSNPSGAAYSAADYRPLLEVLLRHPHVWLLVDDMYEHIVY-DGFRFVTPAQLEPGLKNRT 241 Query: 272 CLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATIL 331 +K + G R+G + + V+SQ S P + L Sbjct: 242 LTVNGVSKAYAMTGWRIGYAGGPRELIKAMAVVQSQAT-------SCPSSISQAASVVAL 294 Query: 332 TSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTG 385 P +K + R +V+ L + + + F+G Sbjct: 295 NGPQDF------LKERTESFQRRRDLVVNGL---NAIDGLDCRVPEGAFYTFSG 339 >1O4S-A nrPDB Length = 389 Score = 131 bits (329), Expect = 6e-31, Method: Composition-based stats. Identities = 62/375 (16%), Positives = 122/375 (32%), Gaps = 40/375 (10%) Query: 36 VEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKE 95 + P + + K + + + A D P P V +A + + + + Sbjct: 18 ISEIPISKTMELDAKAKALIKKGEDVINLTAGEPDFPTPE--PVVEEAVRFL--QKGEVK 73 Query: 96 YLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDV 155 Y G+ E + A+ Q + GA + + +V Sbjct: 74 YTDPRGIYELREGIAKRIGERYK-----KDISPDQVVVTNGAKQALFNAFMALLDPGDEV 128 Query: 156 FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQ-SVLLLHACAH 214 + P W ++ P AG + + K +F +LE++ + + +L + Sbjct: 129 IVFSPVWVSYIPQIILAGGTVNVVETFMSK----NFQPSLEEVEGLLVGKTKAVLINSPN 184 Query: 215 NPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLC 274 NPTGV R E + + + KK+N + D Y D V ++ + Sbjct: 185 NPTGVVYRREFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDR---IVYI 241 Query: 275 QSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSP 334 ++K+ + G RVG +E+ S+++ + T+ Sbjct: 242 NGFSKSHSMTGWRVGYLI----SSEKVATAVSKIQS-----------HTTSCINTVAQYA 286 Query: 335 DLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCF---TGLKPEQV 391 L+ + M + +V LKK G + + + F G + Sbjct: 287 ALKAL-EVDNSYMVQTFKERKNFVVERLKKMGVK----FVEPEGAFYLFFKVRGDDVKFC 341 Query: 392 ERLTKEFSVYMTKDG 406 ERL +E V + Sbjct: 342 ERLLEEKKVALVPGS 356 >1J32-A nrPDB Length = 388 Score = 124 bits (311), Expect = 7e-29, Method: Composition-based stats. Identities = 51/262 (19%), Positives = 88/262 (33%), Gaps = 17/262 (6%) Query: 34 THVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKP-YVLPSVRKAEAQIAAKNL 92 VE P L + K A D P +++ + + A Q Sbjct: 5 ARVESVSPSMTLIIDAKAKAMKAEGIDVCSFSAGEPDFNTPKHIVEAAKAALEQ-----G 59 Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 Y P G +A A+ +N + + G + + + + Sbjct: 60 KTRYGPAAGEPRLREAIAQKLQRDNGLCYGADNI-----LVTNGGKQSIFNLMLAMIEPG 114 Query: 153 RDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDI-SKIPEQSVLLLHA 211 +V +P P W ++ + + A +G P T F + E I I ++ LL+ Sbjct: 115 DEVIIPAPFWVSYPEMVKLA----EGTPVILPTTVETQFKVSPEQIRQAITPKTKLLVFN 170 Query: 212 CAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINV 271 NPTG+ P++ + IA V + L+ D Y+ D + E Sbjct: 171 TPSNPTGMVYTPDEVRAIAQVAVEAGLWVLSDEIYEKILYDDA-QHLSIGAASPEAYERS 229 Query: 272 CLCQSYAKNMGLYGERVGAFTV 293 +C +AK + G RVG Sbjct: 230 VVCSGFAKTYAMTGWRVGFLAG 251 >5WMH-A nrPDB Length = 475 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 69/359 (19%), Positives = 116/359 (32%), Gaps = 30/359 (8%) Query: 6 SSRILSGMAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVG 65 SSRI + L+++ S V+ P + +T+ S + + Sbjct: 49 SSRICAMAKPNDAETLSSSVDMSLSPR---VQSLKPSKTMVITDLAATLVQSGVPVIRLA 105 Query: 66 AYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGR 125 A D P V +A A + Y G+ E +A EN Sbjct: 106 AGEPDFDTP---KVVAEA-GINAIREGFTRYTLNAGITELREAICRKLKEENGLS----- 156 Query: 126 FVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPK 185 + Q + GA + + +V +P P W ++T R A Sbjct: 157 YAPDQILVSNGAKQSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVIP----T 212 Query: 186 TCGFDFSGALEDIS-KIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVV-KKKNLFAFFD 243 +F +D+ K+ E+S LL+ NPTG +EIA ++ K L D Sbjct: 213 KISNNFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLLVLSD 272 Query: 244 MAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKR 303 Y+ ++A + ++K + G R+G + Sbjct: 273 EIYEHIIYAPATHTSFA--SLPDMYERTLTVNGFSKAFAMTGWRLGYLAG----PKHIVA 326 Query: 304 VESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNL 362 S+L+ + S+ A +AA L K + V M R LV +L Sbjct: 327 ACSKLQGQVSSGASSI-AQKAGVAALGLG-----KAGGETVAEMVKAYRERRDFLVKSL 379 >1XI9-A nrPDB Length = 406 Score = 112 bits (279), Expect = 4e-25, Method: Composition-based stats. Identities = 68/336 (20%), Positives = 129/336 (38%), Gaps = 22/336 (6%) Query: 25 ASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAE 84 S RAS VE D +L E K+ ++N+G D ++ + KA Sbjct: 8 GSIRASKRALSVEYAIRDVVLPARELEKKGIKVIRLNIGDPVKFDFQPPEHMKEAYCKAI 67 Query: 85 AQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASF 144 + D E GL E KA E +N + + T AL++ Sbjct: 68 KEGHNYYGDSE-----GLPELRKAIVEREKRKNGVDITPDDVRVTAAV--TEALQLIFGA 120 Query: 145 LQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDIS-KIPE 203 L ++ +P PS+ +T + + G + YR + + D+ ++DI KI + Sbjct: 121 L---LDPGDEILVPGPSYPPYTGLVKFYGGKPVEYRTIEEE----DWQPDIDDIRKKITD 173 Query: 204 QSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRH 263 ++ + +NPTG + +EI ++ + + D Y + +G+ + Sbjct: 174 RTKAIAVINPNNPTGALYDKKTLEEILNIAGEYEIPVISDEIYD-LMTYEGEHISPGS-- 230 Query: 264 FIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNG 323 + + + V + +K G R+G V + + ++ V + L R P Sbjct: 231 -LTKDVPVIVMNGLSKVYFATGWRLGYMYFVDPENKLSE-VREAIDRLARIRL-CPNTPA 287 Query: 324 ARIAATILTSP-DLRKQWLQEVKGMADRIISMRTQL 358 A LT P D K++++++K D I ++ Sbjct: 288 QFAAIAGLTGPMDYLKEYMKKLKERRDYIYKRLNEI 323 >3B46-A nrPDB Length = 447 Score = 104 bits (260), Expect = 7e-23, Method: Composition-based stats. Identities = 53/321 (16%), Positives = 100/321 (31%), Gaps = 35/321 (10%) Query: 60 MNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNE 119 +NLG G + + P ++++A+ + ++ +Y P G + +L N Sbjct: 60 INLGQGFF---SYSPPQF-AIKEAQKALDIPMVN-QYSPTRGRPSLINSLIKLYSPIYNT 114 Query: 120 VLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGY 179 LK+ TGA S L +V + +P + + P G ++ Sbjct: 115 ELKAENVT-----VTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYV 169 Query: 180 RYYDPKTCG----------FDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEI 229 PK DF + I+ + ++ HNP G E+ + Sbjct: 170 PINPPKELDQRNTRGEEWTIDFEQFEKAITSKTKAVII---NTPHNPIGKVFTREELTTL 226 Query: 230 ASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 ++ K N+ D Y+ D E G S K+ G R+G Sbjct: 227 GNICVKHNVVIISDEVYEHLYFTDSFTR--IATLSPEIGQLTLTVGSAGKSFAATGWRIG 284 Query: 290 AFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMAD 349 + A+ + K R +++P A + + + M Sbjct: 285 WVLSL-----NAELLSYAAKAHTRICFASP-SPLQEACANSINDALKIGYFEK----MRQ 334 Query: 350 RIISMRTQLVSNLKKEGSSHN 370 I+ S + G + Sbjct: 335 EYINKFKIFTSIFDELGLPYT 355 >2ZC0-A nrPDB Length = 407 Score = 99.4 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 54/275 (19%), Positives = 93/275 (33%), Gaps = 23/275 (8%) Query: 39 GPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKE--- 95 + V + + + A D R +IA + L+KE Sbjct: 14 IKGSALADVMKKASELQKKGVKLISLAAGDPDPELIP-----RAVLGEIAKEVLEKEPKS 68 Query: 96 --YLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSR 153 Y P G+ E + A ++ + V TI GTGAL + L Sbjct: 69 VMYTPANGIPELREELAAFLKKYDHLEVSPENIVI--TIGGTGALDLLGRVL---IDPGD 123 Query: 154 DVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLH-AC 212 V PS+ N F G +++G + ++++ ++ L+ Sbjct: 124 VVITENPSYINTLLAFEQLGAKIEGVPVDNDGMRVDLLEEKIKELKAKGQKVKLIYTIPT 183 Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC 272 NP GV E+ K + + K +L D AY GD ++ V Sbjct: 184 GQNPMGVTMSMERRKALLEIASKYDLLIIEDTAYNFMRYEGGD---IVPLKALDNEGRVI 240 Query: 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQ 307 + + +K +G G R+G + + E K+V Q Sbjct: 241 VAGTLSKVLG-TGFRIG---WIIAEGEILKKVLMQ 271 >2O0R-A nrPDB Length = 411 Score = 95.9 bits (237), Expect = 3e-20, Method: Composition-based stats. Identities = 64/337 (18%), Positives = 110/337 (32%), Gaps = 35/337 (10%) Query: 34 THVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLD 93 V P E T +NLG G + D++G P +L + + A A Sbjct: 2 ATVSRLRPYATTVFAEMSALATRIGAVNLGQG-FPDEDGPPKMLQAAQDAIA-----GGV 55 Query: 94 KEYLPIGGLAEFCKASAELA---LGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFK 150 +Y P G A +A A G + + + T+ T A+ A+ + + Sbjct: 56 NQYPPGPGSAPLRRAIAAQRRRHFGVDYDPETE----VLVTVGATEAI---AAAVLGLVE 108 Query: 151 FSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKI-PEQSVLLL 209 +V L +P + +++P+ AG F+ + + + ++ L+ Sbjct: 109 PGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRG---FALDADALRRAVTPRTRALI 165 Query: 210 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 269 HNPTG + IA + NL D Y+ + F Sbjct: 166 INSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFD--HARHLPLAGFDGMAE 223 Query: 270 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 329 S AK G ++G C AE V + + L P A A Sbjct: 224 RTITISSAAKMFNCTGWKIG---WACGPAELIAGVRAAKQYL--SYVGGAPFQPAVALAL 278 Query: 330 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEG 366 W V + + + + R +L + L + G Sbjct: 279 DTEDA-----W---VAALRNSLRARRDRLAAGLTEIG 307 >2X5D-A nrPDB Length = 412 Score = 94.7 bits (234), Expect = 6e-20, Method: Composition-based stats. Identities = 65/350 (18%), Positives = 125/350 (35%), Gaps = 41/350 (11%) Query: 25 ASARASSWWTHVEMGPPDPILGVTEAFKRDTN---SKKMNLGVGAYRDDNGKPYVLPSVR 81 A +R + + ++ PP + +T K ++L +G + +G P + Sbjct: 3 AESRPARRFARIDRLPP-YVFNITAELKMAARRRGEDIIDLSMG---NPDGPTP--PHIV 56 Query: 82 KAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVG 141 + +A + Y G+ +A + + +V + TI L Sbjct: 57 EKLCTVAQREDTHGYSTSRGIPRLRRAISHW-YRDRYDVQIDPESEAIVTIGSKEGL--- 112 Query: 142 ASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALE-DISK 200 A + + +P PS+ H AG Q++ G DF LE I + Sbjct: 113 AHLMLATLDHGDTILVPNPSYPIHIYGAVIAGAQVRSVPL----VPGIDFFNELERAIRE 168 Query: 201 IPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWA 260 + +++ NPT + ++ + ++ K+ ++ D+AY DG K Sbjct: 169 SIPKPRMMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYADIVY-DGWKAPSI 227 Query: 261 VRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLY---- 316 ++ + I V + +K+ + G R+G + S L + Y Sbjct: 228 MQVPGAKDIAVEF-FTLSKSYNMAGWRIGFMVG-------NPELVSALARI--KSYHDYG 277 Query: 317 SNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEG 366 + PL A IAA + Q V+ +A + R LV L++ G Sbjct: 278 TFTPLQVAAIAAL--------EGDQQCVRDIARQYQQRRDVLVKGLREAG 319 >1U08-A nrPDB Length = 386 Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 60/356 (16%), Positives = 112/356 (31%), Gaps = 48/356 (13%) Query: 60 MNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASA---ELALGE 116 +NL G + D +G Y+ + +Y P+ G+ +A A E G Sbjct: 33 INLSQG-FPDFDGPRYL-----QERLAHHVAQGANQYAPMTGVQALREAIAQKTERLYG- 85 Query: 117 NNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQL 176 T T AL + + + +V PS+ ++ P +G + Sbjct: 86 ---YQPDADSDITVTAGATEAL---YAAITALVRNGDEVICFDPSYDSYAPAIALSGGIV 139 Query: 177 QGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKK 236 + P D+ +S E++ L++ HNP+ + + + + Sbjct: 140 KRMALQPPHFR-VDWQEFAALLS---ERTRLVILNTPHNPSATVWQQADFAALWQAIAGH 195 Query: 237 NLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLC-QSYAKNMGLYGERVGAFTVVC 295 +F D Y+ + + A Q + S+ K + G +VG Sbjct: 196 EIFVISDEVYEHI---NFSQQGHASVLAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPA 252 Query: 296 KDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMR 355 + E ++V L + N P A L LR + + + D R Sbjct: 253 PISAEIRKVHQYLTFSV-----NTPAQLA------LAD-MLRAEPEHYL-ALPDFYRQKR 299 Query: 356 TQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKP-------EQVERLTKEFSVYMTK 404 LV+ L + + + + F E + LT+E V Sbjct: 300 DILVNALNE----SRLEILPCEGTYFLLVDYSAVSTLDDVEFCQWLTQEHGVAAIP 351 >2GB3-A nrPDB Length = 409 Score = 90.5 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 61/325 (18%), Positives = 114/325 (35%), Gaps = 46/325 (14%) Query: 96 YLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDV 155 Y G+ E +A A +K + T G+ A+ + + ++ Sbjct: 75 YSHSAGIWELREAFASYYKRRQRVDVKPENV--LVTNGGSEAILFSFAVIA---NPGDEI 129 Query: 156 FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHN 215 + +P + N+ + AG++L GF LE + ++L + C N Sbjct: 130 LVLEPFYANYNAFAKIAGVKL--IPVTRRMEEGFAIPQNLESFINERTKGIVLSNPC--N 185 Query: 216 PTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQ 275 PTGV ++ + + + ++ LF D Y A ++ + V + Sbjct: 186 PTGVVYGKDEMRYLVEIAERHGLFLIVDEVYSEIVFRGEFASALSI-----ESDKVVVID 240 Query: 276 SYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPD 335 S +K G RVG + ++ E + ++A L P Sbjct: 241 SVSKKFSACGARVGCL--ITRNEELI-------------------SHAMKLAQGRLAPPL 279 Query: 336 LRKQWLQEVKGMADRI-----ISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQ 390 L + + + D + R ++ + LKK H + T G F T P Sbjct: 280 LEQIGSVGLLNLDDSFFDFVRETYRERVETVLKKLE-EHGLKRFTKPSGAFYITAELP-- 336 Query: 391 VERLTKEFSVYMTKDGRISVAGVTS 415 VE +EF+ +M D ++ G T+ Sbjct: 337 VED-AEEFARWMLTD--FNMDGETT 358 >5YHV-A nrPDB Length = 394 Score = 90.5 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 76/384 (19%), Positives = 124/384 (32%), Gaps = 53/384 (13%) Query: 47 VTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFC 106 + A ++ T+ +NL G + G P VR A A N Y G+ E Sbjct: 27 LAAAERQRTHGDLVNLSAG--QPSAGAP---EPVRAAAAAALHLN-QLGYSVALGIPELR 80 Query: 107 KASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHT 166 A A + ++ V T +G +FL F V + P + + Sbjct: 81 DAIAADYQRRHGITVEPDAVVI--TTGSSGGF--LLAFLA-CFDAGDRVAMASPGYPCYR 135 Query: 167 PIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQW 226 I G ++ P+T + L +I V+ A NPTG PE+ Sbjct: 136 NILSALGCEVVEIPC-GPQTRFQPTAQMLAEIDPPLRGVVV---ASPANPTGTVIPPEEL 191 Query: 227 KEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGE 286 IAS ++ D Y G + + A + N + S++K + G Sbjct: 192 AAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQ----TSRNAVVVNSFSKYYAMTGW 247 Query: 287 RVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKG 346 R+G V + I PP+ ++IAA +P+ + + Sbjct: 248 RLGWLLVPTVLRRAVDCLTGNFTI-------CPPVL-SQIAAVSAFTPEATAEADGNLAS 299 Query: 347 MADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMF-------CFTGLKPEQVERLTKEFS 399 A R+ L+ L++ G + G F FT +L + Sbjct: 300 YA----INRSLLLDGLRRIGI----DRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTG 351 Query: 400 VYMTKDG-----------RISVAG 412 V + RIS AG Sbjct: 352 VAIAPGIDFDTARGGSFVRISFAG 375 >2Z61-A nrPDB Length = 370 Score = 90.5 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 65/386 (16%), Positives = 121/386 (31%), Gaps = 61/386 (15%) Query: 30 SSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA 89 S + E IL + + K ++L +G + KP V ++ + Sbjct: 3 SKRLLNFESFEVMDILALAQKL-ESEGKKVIHLEIGEPDFNTPKPIVDEGIK------SL 55 Query: 90 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASF-LQRF 148 K Y G+ E + +EL + + + TG +G F L Sbjct: 56 KEGKTHYTDSRGILELREKISELYKDKYKADIIPDNIII------TGGSSLGLFFALSSI 109 Query: 149 FKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLL 208 +V + P + + R G + + C F E +S +++ + Sbjct: 110 IDDGDEVLIQNPCYPCYKNFIRFLGAK----PVF----CDFTVESLEEALS---DKTKAI 158 Query: 209 LHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQG 268 + NP G E I + + D Y G + ++ F E Sbjct: 159 IINSPSNPLGEVIDRE----IYEFAYENIPYIISDEIYNGLVY---EGKCYSAIEFDENL 211 Query: 269 INVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAA 328 L ++K + G R+G V+ D + +E+ LK+ S P + Sbjct: 212 EKTILINGFSKLYAMTGWRIG--YVISND----EIIEAILKLQQNLFISAP------TIS 259 Query: 329 TILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHN--------WQHITDQIGM 380 K+ +E+ M R ++ +K G N + +I + Sbjct: 260 QYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNIGEDGRE 319 Query: 381 FCFTGLKPEQVERLTKEFSVYMTKDG 406 F + +L KE V +T Sbjct: 320 FAY---------KLLKEKFVALTPGI 336 >3ELE-A nrPDB Length = 398 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 48/277 (17%), Positives = 92/277 (33%), Gaps = 29/277 (10%) Query: 55 TNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLD---KEYLPIGGLAEFCKASAE 111 + +G N V ++ Y G E A AE Sbjct: 33 GKENVYDFSIG-----NPSIPAPQIVNDTIKELVTDYDSVALHGYTSAQGDVETRAAIAE 87 Query: 112 LALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRD 171 + + T+ +L + L + P + + Sbjct: 88 FLNNTHGTHFNADNLYM--TMGAAASLSICFRALTS--DAYDEFITIAPYFPEYKVFVNA 143 Query: 172 AGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIAS 231 AG +L D + DF E I+ ++ +NP+G E K+++ Sbjct: 144 AGARLVEVPA-DTEHFQIDFDALEERINAHTRGVII---NSPNNPSGTVYSEETIKKLSD 199 Query: 232 VVKK------KNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYG 285 +++K + +F D Y+ DG K + +++ N +C SY+K++ L G Sbjct: 200 LLEKKSKEIGRPIFIIADEPYREIVY-DGIKVPFVTKYYD----NTLVCYSYSKSLSLPG 254 Query: 286 ERVGAFTVVCKDAEEAKRVESQLKILIRPL-YSNPPL 321 ER+G + +V + + + + + R L Y P Sbjct: 255 ERIG-YVLVPDEVYDKAELYAAVCGAGRALGYVCAPS 290 >3PDX-A nrPDB Length = 402 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 42/250 (16%), Positives = 85/250 (34%), Gaps = 15/250 (6%) Query: 42 DPILGVTEAFKRDTNSKK--MNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPI 99 +PI + + K N K ++L +G G P V +A Y P Sbjct: 14 NPIRAIVDNMKVKPNPNKTVISLSIGD-PTVFGNLPTDPEVTQAMKDALDSGKYNGYAPS 72 Query: 100 GGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPK 159 G + A + + T + A+ + + L +++ +P+ Sbjct: 73 IGYLSSREEVASYYHCPEAPLEAKDVIL---TSGCSQAIELCLAVLA---NPGQNILIPR 126 Query: 160 PSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGV 219 P + + + G++++ Y K+ D I E++ L+ NP G Sbjct: 127 PGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLID---EKTACLVVNNPSNPCGS 183 Query: 220 DPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAK 279 ++I +V +++ + D Y D + A + + + C AK Sbjct: 184 VFSKRHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMAT---LSTNVPILSCGGLAK 240 Query: 280 NMGLYGERVG 289 + G R+G Sbjct: 241 RWLVPGWRLG 250 >2DOU-A nrPDB Length = 376 Score = 87.4 bits (215), Expect = 9e-18, Method: Composition-based stats. Identities = 66/378 (17%), Positives = 122/378 (32%), Gaps = 49/378 (12%) Query: 36 VEMGPPDPILGVTEAFKRDTNSKKM---NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNL 92 + P + V + KR + + +L +G + + KA A+ Sbjct: 1 MSRVPEPSVFLVVDEAKRKARERGVGLIDLSIG-----STDLPPPEAPLKALAEALNDPT 55 Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 Y F + +A G L R + I L A L + Sbjct: 56 TYGYCLKSCTLPFLEEAARWYEGRYGVGL-DPRREALALIGSQEGL---AHLLLALTEPE 111 Query: 153 RDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQS----VLL 208 + LP+ ++ ++ R A ++ + L D+ +PE +L Sbjct: 112 DLLLLPEVAYPSYFGAARVASLRTFLIPLREDG---------LADLKAVPEGVWREAKVL 162 Query: 209 LHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQG 268 L +NPTG ++E + +K L+ D Y + +A + Sbjct: 163 LLNYPNNPTGAVADWGYFEEALGLARKHGLWLIHDNPYVDQVY---EGEAPSPLALPGAK 219 Query: 269 INVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAA 328 V S +K+ L G R+G + +RV+ + Y+ G Sbjct: 220 ERVVELFSLSKSYNLAGFRLGFALGSEEALARLERVKGVIDF---NQYAGVLRMGVEA-- 274 Query: 329 TILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKP 388 L +P +EV R+ R ++ K + + M+ + G P Sbjct: 275 --LKTP-------KEVVRGYARVYRERALGMAEALK----GVLSLLPPRATMYLW-GRLP 320 Query: 389 EQVERLTKEFSVYMTKDG 406 E V+ L EF + + + G Sbjct: 321 EGVDDL--EFGLRLVERG 336 >3H14-A nrPDB Length = 391 Score = 86.7 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 49/271 (18%), Positives = 84/271 (30%), Gaps = 21/271 (7%) Query: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97 P ++ V EA +R + + + + + G P +A A+ + Y Sbjct: 10 AVDPFIVMDVMEAARRAEEAGRRIIHMEVGQPGTGAP---RGAVEALAKSLETDA-LGYT 65 Query: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157 GL + A L L GR V T +G + + L F V + Sbjct: 66 VALGLPALRQRIARLYGEWYGVDLDPGRVVI--TPGSSGGFLLAFTAL---FDSGDRVGI 120 Query: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217 P + ++ I R G+ D + + L+ A NPT Sbjct: 121 GAPGYPSYRQILRALGLVPVDLP----TAPENRLQPVPADFAGL--DLAGLMVASPANPT 174 Query: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277 G + + + D Y G + +A AV E + S+ Sbjct: 175 GTMLDHAAMGALIEAAQAQGASFISDEIYHG-----IEYEAKAVTAL-ELTDECYVINSF 228 Query: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQL 308 +K + G RVG V +R+ + Sbjct: 229 SKYFSMTGWRVGWMVVPEDQVRVVERIAQNM 259 >3DYD-A nrPDB Length = 427 Score = 86.3 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 42/250 (16%), Positives = 84/250 (33%), Gaps = 15/250 (6%) Query: 42 DPILGVTEAFKRDTNSKK--MNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPI 99 +PI + + K N K ++L +G G P V +A Y P Sbjct: 37 NPIRAIVDNMKVKPNPNKTMISLSIGD-PTVFGNLPTDPEVTQAMKDALDSGKYNGYAPS 95 Query: 100 GGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPK 159 G + A + + T + A+ + + L +++ +P+ Sbjct: 96 IGFLSSREEIASYYHCPEAPLEAKDVIL---TSGCSQAIDLCLAVLA---NPGQNILVPR 149 Query: 160 PSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGV 219 P + + + G++++ Y K+ D I E++ L+ NP G Sbjct: 150 PGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLID---EKTACLIVNNPSNPCGS 206 Query: 220 DPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAK 279 ++I +V ++ + D Y D + A + + + C AK Sbjct: 207 VFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLAT---LSTDVPILSCGGLAK 263 Query: 280 NMGLYGERVG 289 + G R+G Sbjct: 264 RWLVPGWRLG 273 >2ZJG-A nrPDB Length = 410 Score = 86.3 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 48/245 (19%), Positives = 80/245 (32%), Gaps = 19/245 (7%) Query: 52 KRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAE 111 K + +NLG G + D + YV + KA A I N +Y G KA + Sbjct: 18 KLAADPSVVNLGQG-FPDISPPSYVKEELSKA-AFIDNMN---QYTRGFGHPALVKALSC 72 Query: 112 LALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRD 171 L G+ + + + G+L + +Q +V + P + + P+ R Sbjct: 73 L-YGKIYQRQIDPNEEILVAVGAYGSL---FNSIQGLVDPGDEVIIMVPFYDCYEPMVRM 128 Query: 172 AGMQLQGYRYYDPKTCGFD-------FSGALEDISKIPEQSVLLLHACAHNPTGVDPRPE 224 AG T G F E SK ++ ++ HNP G + Sbjct: 129 AGAVPVFIPLRSKPTDGMKWTSSDWTFDPR-ELESKFSSKTKAIILNTPHNPLGKVYTRQ 187 Query: 225 QWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLY 284 + + IA + K + D Y+ G S K + Sbjct: 188 ELQVIADLCVKHDTLCISDEVYEWLVY-TGHTHVKIAT-LPGMWERTITIGSAGKTFSVT 245 Query: 285 GERVG 289 G ++G Sbjct: 246 GWKLG 250 >4WP0-A nrPDB Length = 472 Score = 85.9 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 44/240 (18%), Positives = 78/240 (32%), Gaps = 19/240 (7%) Query: 58 KKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGEN 117 +NLG G D P +V + ++ + +Y G K A GE Sbjct: 29 DVVNLGQG--FPDFPPPDF--AVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASF-FGEL 83 Query: 118 NEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAG---- 173 + T+ G GAL L +V + +P + + P+ AG Sbjct: 84 LGQEIDPLRNVLVTVGGYGALFTAFQAL---VDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 Query: 174 -MQLQGYRYYDPKTC---GFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEI 229 + L+ + + + E K ++ L+ +NP G E+ + + Sbjct: 141 FVSLKPGPIQNGELGSSSNWQLDPM-ELAGKFTSRTKALVLNTPNNPLGKVFSREELELV 199 Query: 230 ASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 AS+ ++ ++ D YQ DG + S K G +VG Sbjct: 200 ASLCQQHDVVCITDEVYQWMVY-DGHQHISIA-SLPGMWERTLTIGSAGKTFSATGWKVG 257 >3FVS-A nrPDB Length = 422 Score = 85.9 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 44/240 (18%), Positives = 78/240 (32%), Gaps = 19/240 (7%) Query: 58 KKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGEN 117 +NLG G D P +V + ++ + +Y G K A GE Sbjct: 29 DVVNLGQG--FPDFPPPDF--AVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASF-FGEL 83 Query: 118 NEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAG---- 173 + T+ G GAL L +V + +P + + P+ AG Sbjct: 84 LGQEIDPLRNVLVTVGGYGALFTAFQAL---VDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 Query: 174 -MQLQGYRYYDPKTC---GFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEI 229 + L+ + + + E K ++ L+ +NP G E+ + + Sbjct: 141 FVSLKPGPIQNGELGSSSNWQLDPM-ELAGKFTSRTKALVLNTPNNPLGKVFSREELELV 199 Query: 230 ASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 AS+ ++ ++ D YQ DG + S K G +VG Sbjct: 200 ASLCQQHDVVCITDEVYQWMVY-DGHQHISIA-SLPGMWERTLTIGSAGKTFSATGWKVG 257 >1M4N-A nrPDB Length = 435 Score = 82.4 bits (202), Expect = 4e-16, Method: Composition-based stats. Identities = 55/327 (16%), Positives = 108/327 (33%), Gaps = 52/327 (15%) Query: 81 RKAEAQIAAKNLDKEYLPIGGLAEFCKASA---------ELALGENNEVLKSGRFVTVQT 131 + E+ A L ++Y GL F KA ++ N+ VL +G +T Sbjct: 70 KNGESIFAELALFQDY---HGLPAFKKAMVDFMAEIRGNKVTFDPNHLVLTAGATSANET 126 Query: 132 ISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNH-TPIFRDAGMQLQGYRYYDPKTCGFD 190 F+ V +P P + + G+++ Sbjct: 127 ------------FIFCLADPGEAVLIPTPYYPGFDRDLKWRTGVEIVPIHCTSSNGFQIT 174 Query: 191 FSGALEDISKIPEQ---SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQ 247 + E + ++ +L NP G + + S V+ K + D Y Sbjct: 175 ETALEEAYQEAEKRNLRVKGVLVTNPSNPLGTTMTRNELYLLLSFVEDKGIHLISDEIYS 234 Query: 248 GFASGDGDKDAWAVRHFIEQGI--------NVCLCQSYAKNMGLYGERVGAFTVVCKDAE 299 G A + ++ V + S +K++GL G RVGA + + + Sbjct: 235 GTAFSS-PSFISVMEVLKDRNCDENSEVWQRVHVVYSLSKDLGLPGFRVGA---IYSNDD 290 Query: 300 EAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLV 359 +++ + + + +L+ L K ++ E R+ + +LV Sbjct: 291 MVVAAATKM-----SSFGLVSSQTQHLLSAMLSDKKLTKNYIAENH---KRLKQRQKKLV 342 Query: 360 SNLKKEGSSHNWQHITDQIGMFCFTGL 386 S L+K G + G+FC+ + Sbjct: 343 SGLQKSGI----SCLNGNAGLFCWVDM 365 >1IAY-A nrPDB Length = 428 Score = 79.3 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 56/298 (18%), Positives = 91/298 (30%), Gaps = 29/298 (9%) Query: 101 GLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKP 160 GL EF KA A+ ++ V TGA + + +P P Sbjct: 84 GLPEFRKAIAKFMEKTRGGRVRFDPERVVMAGGATGA---NETIIFCLADPGDAFLVPSP 140 Query: 161 SWGNHTPIFR-DAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVL---LLHACAHNP 216 + R G+QL E + ++ L+ NP Sbjct: 141 YYPAFNRDLRWRTGVQLIPIHCESSNNFKITSKAVKEAYENAQKSNIKVKGLILTNPSNP 200 Query: 217 TGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC---- 272 G + K + S + N+ D Y D + EQ + C Sbjct: 201 LGTTLDKDTLKSVLSFTNQHNIHLVCDEIYAA-TVFDTPQFVSIAEILDEQEMTYCNKDL 259 Query: 273 --LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATI 330 + S +K+MGL G RVG D R S ++ A + Sbjct: 260 VHIVYSLSKDMGLPGFRVGIIYSFNDDVVNCARKMSSFGLVS--------TQTQYFLAAM 311 Query: 331 LTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKP 388 L+ +L+E M R+ + L+ G + + G+FC+ L+P Sbjct: 312 LSDEKFVDNFLRE-SAM--RLGKRHKHFTNGLEVVGIK----CLKNNAGLFCWMDLRP 362 >2O1B-A nrPDB Length = 404 Score = 77.8 bits (190), Expect = 8e-15, Method: Composition-based stats. Identities = 70/379 (18%), Positives = 128/379 (33%), Gaps = 55/379 (14%) Query: 41 PDPILGVTEAFK-RDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPI 99 PD G T K +N+ VG D ++ +KA +++Y Sbjct: 30 PDSYFGKTMGRKIEHGPLPLINMAVGI-PDGPTPQGIIDHFQKALTI----PENQKYGAF 84 Query: 100 GGLAEFCKASAELALGENNEVLKSGRFVTVQTISGT--GALRVGASFLQRFFKFSRDVFL 157 G F +A + + N L V + + GT G + V + V L Sbjct: 85 HGKEAFKQAIVDFYQRQYNVTLDKEDEVCI--LYGTKNGLVAVPTCVI----NPGDYVLL 138 Query: 158 PKPSWGNHTPIFRDAGMQLQGY----RYYDPKTCGFDFSGALEDISKIPEQSVLLLHACA 213 P P + ++ A + +Y P D S+I +++ L+ Sbjct: 139 PDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKVD--------SQIIDKTKLIYLTYP 190 Query: 214 HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCL 273 +NPTG E + E + K + D AY F + A + + I + Sbjct: 191 NNPTGSTATKEVFDEAIAKFKGTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEI-- 248 Query: 274 CQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTS 333 S +K + G RVG K + LK ++N + GA L Sbjct: 249 -YSLSKGYNMSGFRVGFAVG-------NKDMIQALKKY--QTHTNAGMFGA------LQD 292 Query: 334 PDLRKQ--WLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFT----GLK 387 + + ++ ++ + R + + L K + + + G++ + G Sbjct: 293 AAIYALNHYDDFLEEQSNVFKTRRDRFEAMLAKA----DLPFVHAKGGIYVWLETPPGYD 348 Query: 388 PEQVER-LTKEFSVYMTKD 405 EQ E+ L +E S+ + Sbjct: 349 SEQFEQFLVQEKSILVAPG 367 >1BW0-A nrPDB Length = 416 Score = 77.8 bits (190), Expect = 9e-15, Method: Composition-based stats. Identities = 49/259 (18%), Positives = 97/259 (37%), Gaps = 13/259 (5%) Query: 42 DPILGVTEAFKRDTNSKKM-NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIG 100 +PI V++ K + K + L VG D ++K + I ++ + Y P Sbjct: 17 NPIRTVSDNAKPSPSPKPIIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECN-GYFPTV 75 Query: 101 GLAEFCKASAELALGENNEVLKSGRFVTVQ---TISGTGALRVGASFLQRFFKFSRDVFL 157 G E +A A N+ V K T+ + +G + + Sbjct: 76 GSPEAREAVA--TWWRNSFVHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALV 133 Query: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPE-QSVLLLHACAHNP 216 P+P + ++ + + G+ + Y D+ L++I ++ + ++ LL+ NP Sbjct: 134 PQPGFPHYETVCKAYGIGMHFY----NCRPENDWEADLDEIRRLKDDKTKLLIVTNPSNP 189 Query: 217 TGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGF-ASGDGDKDAWAVRHFIEQGINVCLCQ 275 G + + ++I + ++ L F D Y G G + E + + Sbjct: 190 CGSNFSRKHVEDIVRLAEELRLPLFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILG 249 Query: 276 SYAKNMGLYGERVGAFTVV 294 AKN+ + G R+G V Sbjct: 250 GTAKNLVVPGWRLGWLLYV 268 >3ASB-A nrPDB Length = 400 Score = 77.4 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 47/242 (19%), Positives = 80/242 (33%), Gaps = 29/242 (11%) Query: 53 RDTNSKKMNLGVGAYRDDNGKPY---VLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKAS 109 + +NL +G D +P V + + A++++ + Y P GL + Sbjct: 29 ENPQHTVINLSIG----DTTQPLNASVAEAFASSIARLSSPTTCRGYGPDFGLPALRQKL 84 Query: 110 AELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIF 169 +E G + GA L FF ++ V + PS+ + I Sbjct: 85 SEDFYR--------GFVDAKEIFISDGAKVDLFRLLS-FFGPNQTVAIQDPSYPAYLDIA 135 Query: 170 RDAGM-QLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKE 228 R G ++ F ED +L +NPTG +Q + Sbjct: 136 RLTGAKEIIALPCLQENAF---FPEFPED-----THIDILCLCSPNNPTGTVLNKDQLRA 187 Query: 229 IASVVKKKNLFAFFDMAYQGFASG-DGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGER 287 I + + FD AY F S K + + S++K +G G R Sbjct: 188 IVHYAIEHEILILFDAAYSTFISDPSLPKSIF---EIPDARFCAIEINSFSKPLGFAGIR 244 Query: 288 VG 289 +G Sbjct: 245 LG 246 >3EI8-A nrPDB Length = 432 Score = 75.9 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 41/246 (16%), Positives = 85/246 (34%), Gaps = 30/246 (12%) Query: 55 TNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELAL 114 +++ ++LG+G + + ++ K +++ Y G A A+ Sbjct: 54 PDAQVISLGIGD-TTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFY 112 Query: 115 G-----ENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIF 169 G +++ + G + S LQ F + + + PS+ + Sbjct: 113 GGLGIGDDDVFVSDGAKCDI-------------SRLQVMFGSNVTIAVQDPSYPAYVDSS 159 Query: 170 RDAGMQLQGYRYYDPKTCGFDF------SGALEDISKIPEQSVLLLHACAHNPTGVDPRP 223 G Q + K ++ +G D+S + + + +NPTG Sbjct: 160 VIMG-QTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDI-IFFCSPNNPTGAAATR 217 Query: 224 EQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGL 283 EQ ++ KK +D AY + S D + + + E + S++ G Sbjct: 218 EQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMET---ASFSNYAGF 274 Query: 284 YGERVG 289 G R+G Sbjct: 275 TGVRLG 280 >4CVQ-A nrPDB Length = 431 Score = 73.6 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 55/309 (17%), Positives = 101/309 (32%), Gaps = 23/309 (7%) Query: 23 AAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSK-KMNLGVGAYRDDNGKPYVLPSVR 81 A + SS +V P+L + + + N K+N+G N P+ + Sbjct: 26 AMSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIG-------NPAPFGFDAPD 78 Query: 82 KAE-AQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTI-SGTGALR 139 + I + Y GL KA + + + R VTV+ I G G Sbjct: 79 EILVDVIRNLPTAQGYCDSKGLYSARKAIMQ------HYQARGMRDVTVEDIYIGNGVSE 132 Query: 140 VGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDIS 199 + +Q ++ +P P + T + + Y + D I+ Sbjct: 133 LIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKIT 192 Query: 200 KIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAW 259 V++ +NPTG E EI + ++ NL F D Y D + + Sbjct: 193 PRTRGIVII---NPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSI 249 Query: 260 AVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVES-QLKILIRPLYSN 318 A + + +K + G R G + +E ++ +R + Sbjct: 250 AP---LAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANV 306 Query: 319 PPLNGARIA 327 P + + A Sbjct: 307 PAQHAIQTA 315 >4FL0-A nrPDB Length = 456 Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 60/336 (17%), Positives = 106/336 (31%), Gaps = 42/336 (12%) Query: 87 IAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQ 146 ++ + Y G KA AE + + + + S LQ Sbjct: 99 LSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFV--------SDGAQSDISRLQ 150 Query: 147 RFFKFSRDVFLPKPSWGNHT---PIFRDAGM---QLQGYRYYDPKTCGFDFSGALEDISK 200 + + + P++ + I G + + Y+ CG + + D++ Sbjct: 151 LLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPN-NSFFPDLAM 209 Query: 201 IPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWA 260 P V + +NPTG +Q ++ K FD AY F + + Sbjct: 210 TPRTDV-IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYE 268 Query: 261 VRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPP 320 + E I V S++K G G R+G + D + R + ++ Sbjct: 269 IPGAREVAIEV---SSFSKFAGFTGVRLGWSII--PDELLYSNGFPIINDFHRIVTTS-- 321 Query: 321 LNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEG--------SSHNWQ 372 NGA A L L+E++ + + R L+ L G + + W Sbjct: 322 FNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWV 381 Query: 373 HITDQIGMFCFTGLKPEQV--ERLTKEFSVYMTKDG 406 H F G K V E L + + G Sbjct: 382 H---------FKGSKSWDVFNEILENTHIITVPGSG 408 >3FFH-A nrPDB Length = 363 Score = 72.8 bits (177), Expect = 3e-13, Method: Composition-based stats. Identities = 56/338 (16%), Positives = 112/338 (33%), Gaps = 54/338 (15%) Query: 76 VLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGT 135 L + +K A A +++ E P G + K A+ E E++ T Sbjct: 43 PLGTSKKVAAIQANSSVETEIYPDGWASSLRKEVADFYQLEEEELIF------------T 90 Query: 136 GALRVGASFLQR-FFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGA 194 + L R + + + P++ + G +++ D G Sbjct: 91 AGVDELIELLTRVLLDTTTNTVMATPTFVQYRQNALIEGAEVREIPLLQDGEH--DLEGM 148 Query: 195 LEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDG 254 L I + V + + +NPTG + V ++ D AY + + Sbjct: 149 LNAIDEKT-TIVWICN--PNNPTGNYIELADIQAFLDRVPS-DVLVVLDEAYIEYVTPQP 204 Query: 255 DKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRP 314 +K VR + N+ + ++++K GL RVG D E +++ ++R Sbjct: 205 EKHEKLVRTY----KNLIITRTFSKIYGLASARVG---YGIADKEIIRQL-----NIVR- 251 Query: 315 LYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKK---EGSSHNW 371 PP N I + + ++ E + I +K ++ N+ Sbjct: 252 ----PPFNTTSIGQKLAIEAIKDQAFIGECRTSNANGIKQYEAFAKRFEKVKLYPANGNF 307 Query: 372 QHI---TDQIGMFCFTGLKPEQVERLTKEFSVYMTKDG 406 I + +F + E + Y+T+ G Sbjct: 308 VLIDLGIEAGTIFSYL------------EKNGYITRSG 333 >1YIY-A nrPDB Length = 429 Score = 72.4 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 33/205 (16%), Positives = 73/205 (35%), Gaps = 11/205 (5%) Query: 90 KNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFF 149 L +Y G +A ++L ++++ + + GA + +Q Sbjct: 67 DPLANQYTRGFGHPRLVQALSKL----YSQLVDRTINPMTEVLVTVGAYEALYATIQGHV 122 Query: 150 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGF----DFSGALEDISKI-PEQ 204 +V + +P + + P+ + AG + KT G D+ ++ + E+ Sbjct: 123 DEGDEVIIIEPFFDCYEPMVKAAGGIPRFIPLKPNKTGGTISSADWVLDNNELEALFNEK 182 Query: 205 SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHF 264 + +++ HNP G + + +A++ KK N+ D Y+ + + Sbjct: 183 TKMIIINTPHNPLGKVMDRAELEVVANLCKKWNVLCVSDEVYEHMVFEPFEH--IRICTL 240 Query: 265 IEQGINVCLCQSYAKNMGLYGERVG 289 S K L G ++G Sbjct: 241 PGMWERTITIGSAGKTFSLTGWKIG 265 >3OP7-A nrPDB Length = 375 Score = 71.6 bits (174), Expect = 6e-13, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 108/322 (33%), Gaps = 49/322 (15%) Query: 95 EYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRD 154 Y I G F K+ ++L G E + +QT TGA L + Sbjct: 58 NYGWIEGSPAFKKSVSQLYTGVKPEQI-------LQTNGATGA---NLLVLYSLIEPGDH 107 Query: 155 VFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAH 214 V P++ I + G ++ ++ + D + I P ++ ++ A+ Sbjct: 108 VISLYPTYQQLYDIPKSLGAEVDLWQIEEENGWLPDLEKLRQLIR--PTTKMICINN-AN 164 Query: 215 NPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLC 274 NPTG +E+ + + + D Y+ F+ + D ++ ++GI V Sbjct: 165 NPTGAVMDRTYLEELVEIASEVGAYILSDEVYRSFS----ELDVPSIIEVYDKGIAV--- 217 Query: 275 QSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIR--PLYSNPPL--NGARIAATI 330 S +K L G R+G Q+ ++R Y+ +A Sbjct: 218 NSLSKTYSLPGIRIGWVAANH-----------QVTDILRDYRDYTMICAGVFDDLVAQLA 266 Query: 331 LTS-----PDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTG 385 L R + + + I LVS ++ S ++ I + M F Sbjct: 267 LAHYQEILERNRHILEENLAILDQWIEE--EPLVSYIRPAVVSTSFVKIAVDMPMEDF-- 322 Query: 386 LKPEQVERLTKEFSVYMTKDGR 407 +L +E V + R Sbjct: 323 -----CLQLLQEHGVLLVPGNR 339 >2ZYJ-A nrPDB Length = 397 Score = 68.6 bits (166), Expect = 5e-12, Method: Composition-based stats. Identities = 66/327 (20%), Positives = 112/327 (34%), Gaps = 55/327 (16%) Query: 95 EYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRD 154 +Y P G A AE V +T TG+ + + F Sbjct: 69 QYSPTEGYAPLRAFVAEWI-----GVRPEEVLIT------TGSQQALDLVGKVFLDEGSP 117 Query: 155 VFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAH 214 V L PS+ FR G + G D E + + + + L+ Sbjct: 118 VLLEAPSYMGAIQAFRLQGPRFLTVP---AGEEGPDLDALEEVLKRERPRFLYLI-PSFQ 173 Query: 215 NPT-GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQG--INV 271 NPT G+ P P + K + +V ++ L D AY+ G + ++ + V Sbjct: 174 NPTGGLTPLPAR-KRLLQMVMERGLVVVEDDAYRELYFG--EARLPSLFELAREAGYPGV 230 Query: 272 CLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATIL 331 S++K + G RV AF V +A L+ L++ GA L Sbjct: 231 IYLGSFSKVLSP-GLRV-AFAVAHPEA---------LQKLVQA------KQGAD-----L 268 Query: 332 TSPDLRKQWLQEV--KGMADRIISMRTQLVSNLK------KEGSSHNWQHITDQIGMFCF 383 +P L + + E+ +G ++R+ +R + ++ + GMF + Sbjct: 269 HTPMLNQMLVHELLKEGFSERLERVRRVYREKAQAMLHALDREVPKEVRYTRPKGGMFVW 328 Query: 384 T----GLKPEQVERLTKEFSVYMTKDG 406 GL E + R E +V G Sbjct: 329 MELPKGLSAEGLFRRALEENVAFVPGG 355 >1IJI-A nrPDB Length = 356 Score = 68.6 bits (166), Expect = 5e-12, Method: Composition-based stats. Identities = 47/240 (19%), Positives = 90/240 (37%), Gaps = 36/240 (15%) Query: 130 QTISGTGALRVGASFLQRFFKFSRD--VFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTC 187 Q + GA ++ F + +D ++ P P++G ++ G++ + D Sbjct: 77 QVLVSRGADEGIELLIRAFCEPGKDAILYCP-PTYGMYSVSAETIGVECRTVPTLD--NW 133 Query: 188 GFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQ 247 D G + + ++ +NPTG P+ ++ + + + K D AY Sbjct: 134 QLDLQGISDKLD----GVKVVYVCSPNNPTGQLINPQDFRTLLELTRGK-AIVVADEAYI 188 Query: 248 GFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQ 307 F A E ++ + ++ +K L G R G + E + Sbjct: 189 EFCP-----QASLAGWLAE-YPHLAILRTLSKAFALAGLRCG---FTLANEEVINLL--- 236 Query: 308 LKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADR---IISMRTQLVSNLKK 364 +K++ S P A IAA L+ Q + M +R II+ R L++ LK+ Sbjct: 237 MKVIAPYPLSTPV---ADIAAQALSP--------QGIVAMRERVAQIIAEREYLIAALKE 285 >4WBT-A nrPDB Length = 376 Score = 68.6 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 78/414 (18%), Positives = 131/414 (31%), Gaps = 54/414 (13%) Query: 26 SARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGK-PYVLPSVRKAE 84 S A S +T + P + V + +K+ +GA G P VL ++R+A Sbjct: 3 SMSAFSRFTPLIQSLPASVPFVGPEALERQHGRKIAARIGANESGFGPAPSVLLAIRQA- 61 Query: 85 AQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASF 144 +Y + L N + G I G + Sbjct: 62 -----AGDTWKYADPENHDLKQALARHLGTSPANIAIGEG-------IDG-----LLGQI 104 Query: 145 LQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQ 204 ++ + V + G +L Y D + D G L + + Sbjct: 105 VRLVVEAGAPVVTSLGGYPTFNYHVAGHGGRLVTVPYADDRE---DLEGLLAAVGRENAP 161 Query: 205 SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHF 264 V L + NP G E+ A + + L D AY A +DA Sbjct: 162 LVYLAN--PDNPMGSWWPAERVVAFAQALPETTLLVL-DEAYCETA----PRDALPPIES 214 Query: 265 IEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGA 324 + NV ++++K GL G R+G A+ + IR + + G Sbjct: 215 LIDKPNVIRARTFSKAYGLAGARIG---YTLSTPGTAQAFDK-----IRNHFGMSRI-GV 265 Query: 325 RIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFT 384 A L D K+ ++ RI + S L S+ N+ D + Sbjct: 266 AAAIAALADQDYLKEVTLKIANSRQRIGRIAAD--SGLAPLPSATNF-VAVDCGKDASY- 321 Query: 385 GLKPEQVERLTKEFSVYMTKDG--------RISVAGVTSGNVGYLAHAIHQVTK 430 V+RL + +++ G RIS A + LA A+ +V + Sbjct: 322 --ARAIVDRLMSDHGIFIRMPGVAPLNRCIRISTA--PDAEMDLLAAALPEVIR 371 >4IX8-A nrPDB Length = 444 Score = 67.8 bits (164), Expect = 8e-12, Method: Composition-based stats. Identities = 36/248 (14%), Positives = 74/248 (29%), Gaps = 8/248 (3%) Query: 43 PILGVTEAFKRDTNSKKMNLGVGAY-RDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGG 101 P+ +T+ K + S K NL + +G V +A + Y P G Sbjct: 52 PLNNLTDNMKP-SRSTKSNLRLSIGDPTVDGNLKTPDIVTEAMVDVVRSGKFNGYPPTVG 110 Query: 102 LAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPS 161 + + + I +G + L ++ + PS Sbjct: 111 ADNLRQVVSTYWRRFCQTKSRQEALKWENVIITSGVSQAIVLALTALCNEGDNILVCAPS 170 Query: 162 WGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDP 221 + ++ + G++ + Y Y DP + ++ ++ NP G + Sbjct: 171 FPHYKSVCDSYGIECRYY-YLDP-SKSWECDLRAAAGMVDSHTKAFVIIN-PSNPCGSNF 227 Query: 222 RPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNM 281 +I ++ + D Y +G + + + + AK Sbjct: 228 SRAHVSDIIDFCQQHQIPLISDEIYAEMVLNNG---IFTSVADFDTNVPRLILGGTAKYQ 284 Query: 282 GLYGERVG 289 G RVG Sbjct: 285 VCPGWRVG 292 >3QGU-A nrPDB Length = 449 Score = 67.8 bits (164), Expect = 9e-12, Method: Composition-based stats. Identities = 63/348 (18%), Positives = 110/348 (31%), Gaps = 39/348 (11%) Query: 33 WTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKP-YVLPSVRKAEAQIAAKN 91 + + G P + ++ N + +G P Y+ ++ KA A +A + Sbjct: 43 FGKLRAGYLFPEIARRRKAHQEKNPDAKIISLGIGDTTEPLPKYIADAMAKAAAGLATRE 102 Query: 92 LDKEYLPIGGLAEFCKASAELALG-----ENNEVLKSGRFVTVQTISGTGALRVGASFLQ 146 Y G +A A G + + G + I Q Sbjct: 103 GYSGYGAEQGQGALREAVASTFYGHAGRAADEIFISDGSKCDIARI-------------Q 149 Query: 147 RFFKFSRDVFLPKPSWGNHTPIFRDAGM----QLQGYRYYDPKTCGFDFSGALEDISKIP 202 F V + PS+ + GM G+ + C D + D+SK Sbjct: 150 MMFGSKPTVAVQDPSYPVYVDTSVMMGMTGDHNGTGFDGIEYMVCNPD-NHFFPDLSKAK 208 Query: 203 EQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASG-DGDKDAWAV 261 + + +NPTG Q E+ + +K +D AY + S D K + + Sbjct: 209 RTDI-IFFCSPNNPTGAAATRAQLTELVNFARKNGSILVYDAAYALYISNPDCPKTIYEI 267 Query: 262 RHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYS---N 318 E I C S++K G G R+G V K ++ + ++ Sbjct: 268 PGADEVAIETC---SFSKYAGFTGVRLGWTVV-------PKALKYANGEPVHADWNRVMT 317 Query: 319 PPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEG 366 NGA L+ + L+E+ M L + + G Sbjct: 318 TCFNGASNIVQAGGLACLQPEGLKEMNAMIKFYKENAQILKTTFTEMG 365 >2ZY2-A nrPDB Length = 544 Score = 67.8 bits (164), Expect = 9e-12, Method: Composition-based stats. Identities = 54/283 (19%), Positives = 88/283 (31%), Gaps = 29/283 (10%) Query: 44 ILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYV---LPSVRKAEAQIAAKNLDKEYLPIG 100 +GV K D + + +RD G ++ L VR A L + I Sbjct: 70 TVGVGGLAKLDGIEGRFERFIAEHRDQEGVKFLGKSLSYVRDQLGLDPAAFLHEMVDGIL 129 Query: 101 G----LAEFCKASAELALGENNE------VLKSGRFVTVQTISGTGALRVGASFL--QRF 148 G + +E + + + GT A+ L Sbjct: 130 GCNYPVPPRMLTVSEQIVRQYIVREMAGGAVPPESVDLFAVEGGTAAMAYIFESLRISGL 189 Query: 149 FKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLL 208 K V + P + + I A L+ + G+ +S A D K P+ + Sbjct: 190 LKAGDKVAIGMPVFTPYIEIPELAQYDLKEVPIHADPDNGWQYSDAELDKLKDPDVKIFF 249 Query: 209 LHACAHNPTGVDPRPEQWKEIASVV--KKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIE 266 NP V + ++V ++ +L D Y FA D + F Sbjct: 250 CVN-PSNPPSVKMDQRSLDRVRAIVAEQRPDLLILTDDVYGTFA------DEFQS-LFSV 301 Query: 267 QGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEA-KRVESQL 308 N L S++K G G R+G V+ + SQL Sbjct: 302 CPRNTLLVYSFSKYFGATGWRLG---VIAAHKDNVFDHALSQL 341 >3HDO-A nrPDB Length = 360 Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 62/350 (17%), Positives = 112/350 (32%), Gaps = 56/350 (16%) Query: 69 DDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVT 128 ++N P V+ ++ P + + + EL G + + Sbjct: 34 NENPYPPSPEVVKAILEELGPDGAALRIYPSASSQKLREVAGEL-YGFDPSWI------- 85 Query: 129 VQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCG 188 I G+ V + ++ F ++ PS+ + + G +++ + T Sbjct: 86 ---IMANGSDEVLNNLIRAFAAEGEEIGYVHPSYSYYGTLAEVQGARVRTFGL----TGD 138 Query: 189 FDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQG 248 F +G E + + P G E E+A ++ D Y Sbjct: 139 FRIAGFPERYEG-----KVFFLTTPNAPLGPSFPLEYIDELA---RRCAGMLVLDETYAE 190 Query: 249 FASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQL 308 FA + + + NV + ++ +K+ L G R+G V + L Sbjct: 191 FAESN-------ALELVRRHENVVVTRTLSKSYSLAGMRIGLAI-------ARPEVIAAL 236 Query: 309 KILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEG-- 366 IR Y+ L A A L + RI R + L+ G Sbjct: 237 DK-IRDHYNLDRLAQAACVAA-LRDQAY-------LSECCRRIRETREWFTTELRSIGYD 287 Query: 367 ---SSHNWQHI--TDQIGMFCFTGLKPEQVERLTKEFSVYMTKDG-RISV 410 S N+ D+ G + GL +V L + FS + G RIS+ Sbjct: 288 VIPSQGNYLFATPPDRDGKRVYDGLYARKV--LVRHFSDPLLAHGMRISI 335 >3AV7-A nrPDB Length = 448 Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 52/343 (15%), Positives = 110/343 (32%), Gaps = 36/343 (10%) Query: 71 NGKPYVLPSVRKAEAQIAAKNLDK--EYLPIGGLAEFCKASAELALGENNEVLKSGRFVT 128 N K + +R +I K DK +Y G + + LG+ + + + Sbjct: 87 NPKTFPKEIIRDILVEIMEKYADKALQYGTTKGFTPLRETLMKW-LGKRYGISQDNDIMI 145 Query: 129 VQTISGTGALRVGASFLQR-FFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTC 187 T + + R F V + P++ F Q D Sbjct: 146 ------TSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLDDEGMK 199 Query: 188 GFDFSGALEDISKIPEQSVLLLHACA-HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAY 246 L+++ ++ ++ NP GV ++ K + + + + D Y Sbjct: 200 VEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPY 259 Query: 247 QGF-ASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVE 305 SG+ +K A+ + V +++K + G R+G D + Sbjct: 260 GELRYSGNPEKKIKAL----DNEGRVIYLGTFSKIL-APGFRIGWMVG---DPGIIR--- 308 Query: 306 SQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKE 365 +++I + + G +A + L + + + R ++ L++ Sbjct: 309 -KMEIAKQSTDLCTNVFGQVVAWRYVDGGYL----EKHIPEIRKFYKPRRDAMLEALEEF 363 Query: 366 GSSH-NWQHITDQIGMFCFTGL-----KPEQVERLTKEFSVYM 402 W + GMF + L + +ER K+ Y+ Sbjct: 364 MPEGVKWT--KPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYV 404 >1X0M-A nrPDB Length = 403 Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 52/343 (15%), Positives = 110/343 (32%), Gaps = 36/343 (10%) Query: 71 NGKPYVLPSVRKAEAQIAAKNLDK--EYLPIGGLAEFCKASAELALGENNEVLKSGRFVT 128 N K + +R +I K DK +Y G + + LG+ + + + Sbjct: 42 NPKTFPKEIIRDILVEIMEKYADKALQYGTTKGFTPLRETLMKW-LGKRYGISQDNDIMI 100 Query: 129 VQTISGTGALRVGASFLQR-FFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTC 187 T + + R F V + P++ F Q D Sbjct: 101 ------TSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLDDEGMK 154 Query: 188 GFDFSGALEDISKIPEQSVLLLHACA-HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAY 246 L+++ ++ ++ NP GV ++ K + + + + D Y Sbjct: 155 VEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPY 214 Query: 247 QGF-ASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVE 305 SG+ +K A+ + V +++K + G R+G D + Sbjct: 215 GELRYSGNPEKKIKAL----DNEGRVIYLGTFSKIL-APGFRIGWMVG---DPGIIR--- 263 Query: 306 SQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKE 365 +++I + + G +A + L + + + R ++ L++ Sbjct: 264 -KMEIAKQSTDLCTNVFGQVVAWRYVDGGYL----EKHIPEIRKFYKPRRDAMLEALEEF 318 Query: 366 GSSH-NWQHITDQIGMFCFTGL-----KPEQVERLTKEFSVYM 402 W + GMF + L + +ER K+ Y+ Sbjct: 319 MPEGVKWT--KPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYV 359 >3EZS-A nrPDB Length = 376 Score = 66.6 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 46/273 (16%), Positives = 85/273 (31%), Gaps = 21/273 (7%) Query: 40 PPDPILGVTEAFKRDTNSKK-MNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLP 98 P P + K T K+ ++LG+G + + + + P Sbjct: 5 EPYPFERLRALLKEITPKKRGLDLGIGE--------PQFETPKFIQDALKNHTHSLNIYP 56 Query: 99 IGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASF-LQRFFKFSRDVFL 157 E +A+ ++ + T+ L SF L + + Sbjct: 57 KSAFEESLRAAQRGFFKRRFKIELKEN-ELISTLGSREVLFNFPSFVLFDYQNP--TIAY 113 Query: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217 P P + I+ A ++ P T DF+ +L + ++ E +++L+ +NPT Sbjct: 114 PNPFY----QIYEGAAKFIKAKSLLMPLTKENDFTPSLNE-KELQEVDLVILN-SPNNPT 167 Query: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFI--EQGINVCLCQ 275 G E+ + K + D Y E NV + Sbjct: 168 GRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACMLAGNEAFKNVLVIH 227 Query: 276 SYAKNMGLYGERVGAFTVVCKDAEEAKRVESQL 308 S +K G R G + E+ K + L Sbjct: 228 SLSKRSSAPGLRSGFIAGDSRLLEKYKAFRAYL 260 >3NRA-A nrPDB Length = 407 Score = 65.1 bits (157), Expect = 5e-11, Method: Composition-based stats. Identities = 61/326 (18%), Positives = 103/326 (31%), Gaps = 45/326 (13%) Query: 94 KEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSR 153 EY G+ + + LA V R + T GAL + + Sbjct: 75 TEYRGDLGIRDLL--APRLAAFTGAPV--DARDGLIITPGTQGALFL---AVAATVARGD 127 Query: 154 DVFLPKPSWGNHTPIFRDAGMQLQG----YRYYDPKTCGFDFSGALEDISKIPEQSVLLL 209 V + +P + + + ++ Y D G D +G E + + L Sbjct: 128 KVAIVQPDYFANRKLVEFFEGEMVPVQLDYVSADETRAGLDLTGLEEAFKA---GARVFL 184 Query: 210 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 269 + +NP GV E+ +IA++ + D Y ++ Sbjct: 185 FSNPNNPAGVVYSAEEIGQIAALAARYGATVIADQLYSRLRYAGASYTHLRAEAAVDAE- 243 Query: 270 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 329 NV +K L G R+G +++++ + L YS L G Sbjct: 244 NVVTIMGPSKTESLSGYRLGVAFGSRAIIARMEKLQAIV-SLRAAGYSQAVLRG------ 296 Query: 330 ILTSPDLRKQWLQEVKG-MADRIIS---MRTQLVSNLKKEGSSHNWQHITDQIGMFCFTG 385 W E G M DRI +R +L+ L+ G + Q G + F Sbjct: 297 ----------WFDEAPGWMEDRIARHQAIRDELLHVLR--GCEGVFARTP-QAGSYLFPR 343 Query: 386 LKP------EQVERLTKEFSVYMTKD 405 L E V+ L + V +T Sbjct: 344 LPKLAVAPAEFVKILRLQAGVVVTPG 369 >3TCM-A nrPDB Length = 500 Score = 64.7 bits (156), Expect = 8e-11, Method: Composition-based stats. Identities = 56/315 (17%), Positives = 99/315 (31%), Gaps = 28/315 (8%) Query: 68 RDDNGKPYVLPSVRKAEAQIAAKNLDKE--YLPIGGLAEFCKASAELALGENNEVLKSGR 125 R++ + S+ +A+ +A Y G+ A A + + Sbjct: 100 REEIKTLFSADSISRAKQILAMIPGRATGAYSHSQGIHGLRDAIASGIASRDGFPANADD 159 Query: 126 FVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPK 185 T + + + L R + +P P + ++ G L Y + Sbjct: 160 IFL--TDGASPGVHLMMQLLIR--NEKDGILVPIPQYPLYSASIALHGGALVPYYLNEST 215 Query: 186 TCGF---DFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFF 242 G D LED L+ NPTG E +I K + L Sbjct: 216 GWGLETSDVKKQLEDARSRGINVRALVVINPGNPTGQVLAEENQYDIVKFCKNEGLVLLA 275 Query: 243 DMAYQGFASGDGDK-DAW--AVRHF--IEQGINVCLCQSYAKNMGLYGE---RVGAFTVV 294 D YQ D K ++ VR E+ + + QS +K G YGE R G F + Sbjct: 276 DEVYQENIYVDNKKFHSFKKIVRSLGYGEEDLPLVSYQSVSK--GYYGECGKRGGYFEIT 333 Query: 295 CKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSP----DLRKQWLQEVKGMADR 350 A +++ + + + G +A+ ++ P + + E G+ Sbjct: 334 GFSAPVREQIYKIASVNLCSNIT-----GQILASLVMNPPKASDESYASYKAEKDGILAS 388 Query: 351 IISMRTQLVSNLKKE 365 + L K Sbjct: 389 LARRAKALEHAFNKL 403 >3IF2-A nrPDB Length = 444 Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 53/287 (18%), Positives = 97/287 (33%), Gaps = 38/287 (13%) Query: 94 KEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKF-- 151 Y G + F A + L S T A + F Sbjct: 77 ANYSNPQGDSAFIDALVGFFNRHYDWNLTSENIAL--TNGSQNAFFYLFNLFGGAFVNEH 134 Query: 152 ---------SRDVFLP-KPSWGNHTPIFRDAGMQLQGYRYYDPKTCG---------FDFS 192 + + LP P + ++ + + + D T DF Sbjct: 135 SQDKESKSVDKSILLPLTPEYIGYSDVHVEGQHFAAVLPHIDEVTHDGEEGFFKYRVDFE 194 Query: 193 GALEDISKIPEQSV-LLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFAS 251 ALE++ + E + + + NPTG E+ +A + K+ ++ D AY Sbjct: 195 -ALENLPALKEGRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYGMPFP 253 Query: 252 GDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKIL 311 DA + N LC S +K +GL G R G ++ DA+ + V + ++ Sbjct: 254 NIIYSDAH-----LNWDNNTILCFSLSK-IGLPGMRTG---IIVADAKVIEAVSAMNAVV 304 Query: 312 IRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQL 358 P GA IA ++ + +++ E+K + ++ +L Sbjct: 305 NLA----PTRFGAAIATPLVANDRIKQLSDNEIKPFYQKQATLAVKL 347 >6HNV-A nrPDB Length = 524 Score = 63.5 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 59/368 (16%), Positives = 115/368 (31%), Gaps = 71/368 (19%) Query: 95 EYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRD 154 +Y + G A + + + + + T + L A F Sbjct: 129 QYAAVEGHAPLLQFARDFIIRTHKPNYDDWNVFI--TTGASDGLNKAADV---FLDDGDV 183 Query: 155 VFLPKPSWGNHTPIFRDAGMQLQGYRY-YDPKTCGFDFSGALEDISK-------IPEQSV 206 + + + ++ +AG + + +D + G D + ++ + +P+ Sbjct: 184 ILVEEFTFSPFLRFSDNAGAKAVPVKINFDNDSDGIDLTQFVDLLENWEKHYPNLPKPKA 243 Query: 207 LLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAY-------------QGFASG- 252 L A NPTG E K+I + K + D Y G SG Sbjct: 244 LYTIATGQNPTGFTQSLEFRKKIYDLAVKYDFAIIEDDPYGYLTLPKYEKPNIGGSGSGN 303 Query: 253 -----DGDKDAWAVRHFIEQGIN------VCLCQSYAKNMGLYGERVGAFTVVCKDAEEA 301 D + D + H + V ++++K G R+G E Sbjct: 304 NELKNDLEIDDYLKNHLTPSYLELDTTGRVLRVETFSKLF-APGLRLGFIVG---HKEVI 359 Query: 302 KRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMR------ 355 V+ YS+ GA + + +++ + V G + I+ MR Sbjct: 360 DAVK---------NYSDVVNRGASGLTQTIVNNVIQENFKG-VDGWLEWILKMRLNYSYR 409 Query: 356 --TQLVSNLKKEGSSHNW-QHITDQIGMF-CFTGLKPEQVERLTK---------EFSVYM 402 L S + + + I + GMF F P+ V+ L K + + + Sbjct: 410 KDLLLYSIFESQAYKKGYVDVIDPKAGMFVTFKINLPKDVDVLQKMKLLLWKLISYGILV 469 Query: 403 TKDGRISV 410 ++V Sbjct: 470 VPGYNMTV 477 >4GDY-A nrPDB Length = 439 Score = 63.2 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 46/275 (16%), Positives = 84/275 (30%), Gaps = 36/275 (13%) Query: 41 PDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDK------ 94 P PI +T+ R K + + + +V E + ++ Sbjct: 16 PSPIRTMTDILSRGP---KSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRAL 72 Query: 95 EYLPIGGLAEFCKASAELALGENNEVL-----KSGRFVTVQTISGTGALRVGASFLQRFF 149 +Y P G+ E +L + +N G+ T +G+ + + Sbjct: 73 QYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVT---SGSQQGLCKVFEMII 129 Query: 150 KFSRDVFLPKPSWGN-----HTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQ 204 +V L +P++ H + ED + Sbjct: 130 NPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKN 189 Query: 205 SVLLLHACAH--NPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQ--GFASGDGDKDAWA 260 + L+ + NPTG E+ KEI + +K + D Y F SG Sbjct: 190 TPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPT---- 245 Query: 261 VRHFIEQGI--NVCLCQSYAKNMGLYGERVGAFTV 293 F+ + V S++K + G R+G T Sbjct: 246 ---FLSMDVDGRVIRADSFSKIISS-GLRIGFLTG 276 >1UU1-A nrPDB Length = 335 Score = 62.8 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 59/347 (17%), Positives = 120/347 (34%), Gaps = 61/347 (17%) Query: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97 M P D I ++ + K L + ++N P+ V + ++ + L Y Sbjct: 1 MNPLDLIAKRAYPYETEKR-DKTYLAL----NENPFPFPEDLVDEVFRRLNSDALRIYYD 55 Query: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157 + ++ + + L G GA + + F R VF Sbjct: 56 SPD-----EELIEKILSYLDTDFLSKNNVS-----VGNGADEIIYVMMLMF---DRSVFF 102 Query: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217 P P++ + + G + + ++ + E V+ + +NPT Sbjct: 103 P-PTYSCYRIFAKAVGAKFLEVP--------LTKDLRIPEV-NVGEGDVVFIPN-PNNPT 151 Query: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277 G E+ + I K F D AY F G+ D F+++ N+ + +++ Sbjct: 152 GHVFEREEIERIL----KTGAFVALDEAYYEF-HGESYVD------FLKKYENLAVIRTF 200 Query: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLR 337 +K L +RVG +E+ +++++ Y + A L ++ Sbjct: 201 SKAFSLAAQRVGYVVA----SEKFIDAYNRVRLPFNVSYVS-----QMFAKVALDHREIF 251 Query: 338 KQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFT 384 ++ + + +R+ S L++ G ITD G F F Sbjct: 252 EERTKFIVEERERMKS-------ALREMGY-----RITDSRGNFVFV 286 >4R2N-A nrPDB Length = 367 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 44/214 (20%), Positives = 72/214 (33%), Gaps = 22/214 (10%) Query: 76 VLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGT 135 LPSVR A + P G + A A LG + G Sbjct: 37 PLPSVRAAIDRATDTVNRY---PDNGCVQLKAALAR-HLGPD---FAPEHVA-----VGC 84 Query: 136 GALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGAL 195 G++ + +Q +V S+ + P R AG D FD Sbjct: 85 GSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHT---FDLYAM- 140 Query: 196 EDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGD 255 ++ + +++ L+ +NPT P+ V L A D AY + Sbjct: 141 --LATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAI-DEAYVEYIRDGMR 197 Query: 256 KDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 D+ + NV + ++++K GL G R+G Sbjct: 198 PDSLG---LVRAHNNVVVLRTFSKAYGLAGLRIG 228 >1VP4-A nrPDB Length = 425 Score = 62.0 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 69/371 (18%), Positives = 123/371 (33%), Gaps = 47/371 (12%) Query: 56 NSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEY------LPIGGLAEFCKAS 109 + K + G D RK A+IA + ++KEY G + Sbjct: 40 AADKDAISFGGGVPDPETFP-----RKELAEIAKEIIEKEYHYTLQYSTTEGDPVLKQQI 94 Query: 110 AELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIF 169 +L + T+ AL + F L P++ F Sbjct: 95 LKLLERMYGITGLDED-NLIFTVGSQQALDLIGKL---FLDDESYCVLDDPAYLGAINAF 150 Query: 170 RDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPE----QSVLLLHACAHNPTGVDPRPEQ 225 R D L + K + + + ++ HNP GV E+ Sbjct: 151 RQYLANFVVVPLEDDGMDLNVLERKLSEFDKNGKIKQVKFIYVVSNF-HNPAGVTTSLEK 209 Query: 226 WKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYG 285 K + + +K +LF D Y G +G+ + + V L +++K + G Sbjct: 210 RKALVEIAEKYDLFIVEDDPY-GALRYEGETVDPIFKIGGPE--RVVLLNTFSKVL-APG 265 Query: 286 ERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVK 345 R+G V K V+++ + P R+AA L DL +Q +K Sbjct: 266 LRIG--MVAGSKEFIRKIVQAKQSADL-----CSPAITHRLAARYLERYDLLEQ----LK 314 Query: 346 GMADRIISMRTQLVSNLKKEGS---SHNWQHITDQIGMFCFTGL-----KPEQVERLTKE 397 + RT +++ L++ S W + + G+F + L E E ++ Sbjct: 315 PTIELYRRKRTVMLNALEEYFSDIPGVKW--VKSEGGLFIWLTLPEGFDTWEMFEYAKRK 372 Query: 398 FSVYMTKDGRI 408 Y+ GR+ Sbjct: 373 KVFYV--PGRV 381 >2ZY3-A nrPDB Length = 546 Score = 61.6 bits (148), Expect = 6e-10, Method: Composition-based stats. Identities = 46/263 (17%), Positives = 81/263 (30%), Gaps = 25/263 (9%) Query: 44 ILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYV---LPSVRKAEAQIAAKNLDKEYLPIG 100 +GV K D + + RD G ++ L VR A L + I Sbjct: 71 TVGVGGLAKIDGIEGRFERYIAENRDQEGVRFLGKSLSYVRDQLGLDPAAFLHEMVDGIL 130 Query: 101 G----LAEFCKASAELALGEN------NEVLKSGRFVTVQTISGTGALRVGASFLQR--F 148 G + +E + + + + S GT A+ L+ Sbjct: 131 GCNYPVPPRMLNISEKIVRQYIIREMGADAIPSESVNLFAVEGGTAAMAYIFESLKLNGL 190 Query: 149 FKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLL 208 K V + P + + I A L+ + + + + D K P + Sbjct: 191 LKAGDKVAIGMPVFTPYIEIPELAQYALEEVAINADPSLNWQYPDSELDKLKDPAIKIFF 250 Query: 209 LHACAHNPTGVDPRPEQWKEIASVVKKK--NLFAFFDMAYQGFASGDGDKDAWAVRHFIE 266 NP V + + ++V + +L D Y G D ++ Sbjct: 251 CVN-PSNPPSVKMDQRSLERVRNIVAEHRPDLMILTDDVY-----GTFADDFQSLFAICP 304 Query: 267 QGINVCLCQSYAKNMGLYGERVG 289 + N L S++K G G R+G Sbjct: 305 E--NTLLVYSFSKYFGATGWRLG 325 >3CQ5-A nrPDB Length = 369 Score = 61.2 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 39/236 (16%), Positives = 70/236 (29%), Gaps = 17/236 (7%) Query: 57 SKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGE 116 + ++N+ + ++N P V A + + P E A + Sbjct: 26 APQLNVDIRLNTNENPYPPSEALVADLVATVDKIATELNRYPERDAVELRDELAAYITKQ 85 Query: 117 NNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQL 176 + G+ + LQ F R +PS+ H + G Sbjct: 86 TGVAVTRDNLWAA-----NGSNEILQQLLQAFGGPGRTALGFQPSYSMHPIL--AKGTHT 138 Query: 177 QGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKK 236 + D ALE+I V + +NPTG + + I +V Sbjct: 139 EFIAVSRGADFRIDMDVALEEIRAKQPDIVFV--TTPNNPTGDVTSLDDVERIINVA--- 193 Query: 237 NLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFT 292 D AY F+ A + + + ++ +K G R+G F Sbjct: 194 PGIVIVDEAYAEFSPS-----PSATTLLEKYPTKLVVSRTMSKAFDFAGGRLGYFV 244 >3IHJ-A nrPDB Length = 498 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 45/276 (16%), Positives = 90/276 (32%), Gaps = 18/276 (6%) Query: 71 NGKPYVLPSVRKAEAQIAAKNLDK--EYLPIGGLAEFCKASAELALGENNEVLKSGRFVT 128 + + + ++A + A + Y G+ + A + V + Sbjct: 98 DSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIY 157 Query: 129 VQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTC- 187 + T + G + + K V +P P + ++ + + Y Y D + C Sbjct: 158 LTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNY-YLDEENCW 216 Query: 188 GFDFSGALEDISKIPE--QSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMA 245 + + + + + +L NPTG + +++ ++ LF D Sbjct: 217 ALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEV 276 Query: 246 YQGFASGDGDKDAWAVRHFIEQGIN----VCLCQ--SYAKN-MGLYGERVGAFTVVCKDA 298 YQ + + E G V L S +K MG G R G V+ Sbjct: 277 YQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHP 336 Query: 299 EEAKRVESQLKILIRPLYSNPPLNGARIAATILTSP 334 E ++ L +R PP++G ++ P Sbjct: 337 EIKGQLVKLL--SVRL---CPPVSGQAAMDIVVNPP 367 >3JTX-A nrPDB Length = 396 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 49/273 (17%), Positives = 93/273 (34%), Gaps = 34/273 (12%) Query: 84 EAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGAS 143 +A A+ + ++Y GL E +A A + + + + AL S Sbjct: 50 DALTASLHELEKYPLTAGLPELRQACANWLKRRYDGLTVDADNEILPVLGSREAL---FS 106 Query: 144 FLQRFFKFSRD-----VFLPKPSWGNHTPIFRDAGMQL----QGYRYYDPKTCGFDFSGA 194 F+Q D + P P + + G ++ ++P Sbjct: 107 FVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSIS---- 162 Query: 195 LEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDG 254 ++ +++ L+ +NP+G + WKE+ + K D Y DG Sbjct: 163 ----EEVWKRTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSEI-YFDG 217 Query: 255 DKDAWAVRHFIEQG---INVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKIL 311 +K ++ + G + + S +K + G R G V DAE K L Sbjct: 218 NKPLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGLRSG---FVAGDAELLKNFL--LYRT 272 Query: 312 IRPLYSNPPLNGARIAA-----TILTSPDLRKQ 339 + P+ A IAA ++ + L ++ Sbjct: 273 YHGSAMSIPVQRASIAAWDDEQHVIDNRRLYQE 305 >1WST-A nrPDB Length = 417 Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 48/335 (14%), Positives = 111/335 (33%), Gaps = 30/335 (8%) Query: 72 GKPYVLPSVRKAEAQIAAKNLDK--EYLPIGGLAEFCKASAELALGENNEVLKSGRFVTV 129 + + + +++K ++ ++ DK +Y G A A + + +TV Sbjct: 53 PETFPVETIKKIAVEVLEEHADKALQYGTTKGFTPLRLALARWMEKRYDIPMSKVEIMTV 112 Query: 130 QTISGTGALRVGASFLQR-FFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCG 188 + + R F + + P++ F+ + D K Sbjct: 113 A------GSQQALDLIGRVFLNPGDPIVVEAPTYLAAIQAFKYYDPEFISIPL-DDKGMR 165 Query: 189 FDFSGALEDISKIPEQSVLLLHACAH--NPTGVDPRPEQWKEIASVVKKKNLFAFFDMAY 246 D + + + V +++ + NP GV ++ K++ + + + D Y Sbjct: 166 VDLLEEKLEELRKQGKRVKIVYTVSTFQNPAGVTMSVDRRKKLLELANEYDFLIVEDGPY 225 Query: 247 QGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVES 306 ++HF + G V +++K + G R+G + Sbjct: 226 SELRYSGEPT--PPIKHFDDYG-RVIYLGTFSKIL-APGFRIGWV-------AAHPHLIR 274 Query: 307 QLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEG 366 +++I + + G IA + + L + + ++ R R ++ L++ Sbjct: 275 KMEIAKQSIDLCTNTFGQAIAWKYVENGYLDEHIPKIIEFYKPR----RDAMLEALEEYM 330 Query: 367 SSH-NWQHITDQIGMFCFTGLKPEQVERLTKEFSV 400 W + GMF L +L E +V Sbjct: 331 PEGVEWT--KPEGGMFVRVTLPEGIDTKLMMERAV 363 >3FDD-A nrPDB Length = 533 Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 49/276 (17%), Positives = 81/276 (29%), Gaps = 28/276 (10%) Query: 43 PILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYV---LPSVRKAEAQIAAKNLDKEYLPI 99 +GV K + + + RD G ++ L VR A L + I Sbjct: 70 NTVGVGGLAKIEGIEGRFERYIAENRDQEGVRFLGKSLSYVRDQLGLDPAAFLHEMVDGI 129 Query: 100 GG----LAEFCKASAELALGEN------NEVLKSGRFVTVQTISGTGALRVGASFLQ--R 147 G + +E + + + + S GT A+ ++ Sbjct: 130 LGCNYPVPPRMLNISEKIVRQYIIREMGADAIPSESVNLFAVEGGTAAMAYIFESMKVNG 189 Query: 148 FFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVL 207 K V + P + + I A L+ + + + D K P + Sbjct: 190 LLKAGDKVAIGMPVFTPYIEIPELAQYALEEVAINADPALNWQYPDSELDKLKDPAIKIF 249 Query: 208 LLHACAHNPTGVDPRPEQWKEIASVVKKK--NLFAFFDMAYQGFASGDGDKDAWAVRHFI 265 NP V + + +V + +L D Y FA G F Sbjct: 250 FCVN-PSNPPSVKMDERSLERVRKIVAEHRPDLMILTDDVYGTFADG-------FQSLFA 301 Query: 266 EQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEA 301 N L S++K G G R+G VV E Sbjct: 302 ICPANTLLVYSFSKYFGATGWRLG---VVAAHKENI 334 >3DZZ-A nrPDB Length = 391 Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 37/281 (13%), Positives = 91/281 (32%), Gaps = 21/281 (7%) Query: 131 TISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYR-YYDPKTCGF 189 + +G + ++ +++F + + +P + + G ++ Y+ Sbjct: 88 CVFASGVVPAISAMVRQFTSPGDQILVQEPVYNMFYSVIEGNGRRVISSDLIYENSKYSV 147 Query: 190 DFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGF 249 +++ E + +++ HNP G E+ K IA + K + D + Sbjct: 148 NWADLEEKL--ATPSVRMMVFCNPHNPIGYAWSEEEVKRIAELCAKHQVLLISDEIHGDL 205 Query: 250 ASGDGD-KDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQ- 307 D D A+ V + + + S +K L + + + R E Sbjct: 206 VLTDEDITPAFTVDWDAKNWVVSLI--SPSKTFNLAALHAACAII--PNPDLRARAEESF 261 Query: 308 -LKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKG-MADRIISMRTQLVSNLKKE 365 L + P + + + WL+E+K + D R L + + Sbjct: 262 FLAGIGEPN--------LLAIPAAIAAYEEGHDWLRELKQVLRDNFAYAREFLAKEVPEV 313 Query: 366 GSSHNWQHITDQIGMFCFTGLKPEQ-VERLTKEFSVYMTKD 405 + + + G+ E + L ++ + ++ Sbjct: 314 KVLDSNASYLAWVDI-SALGMNAEDFCKYLREKTGLIISAG 353 >3F6T-A nrPDB Length = 533 Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 38/193 (19%), Positives = 65/193 (33%), Gaps = 16/193 (8%) Query: 109 SAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQ--RFFKFSRDVFLPKPSWGNHT 166 EL+ + N ++ F T GT A+ L K + + +P + + Sbjct: 151 LQELSYKDANLAEQTDLFP---TEGGTAAIVYAFHSLAENHLLKKGDKIAINEPIFTPYL 207 Query: 167 PIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSV-LLLHACAHNPTGVDPRPEQ 225 I +L + + ++ +I K+ + S+ L+ NPT + Sbjct: 208 RIPELKDYELVEVDLHSYEKNDWEIEP--NEIEKLKDPSIKALIVVNPTNPTSKEFDTNA 265 Query: 226 WKEIASVV-KKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLY 284 I V K L D Y F + V + N L SY+K G Sbjct: 266 LNAIKQAVEKNPKLMIISDEVYGAFVP-NFKSIYSVVPY------NTMLVYSYSKLFGCT 318 Query: 285 GERVGAFTVVCKD 297 G R+G + K+ Sbjct: 319 GWRLGVIALNEKN 331 >1D2F-A nrPDB Length = 390 Score = 58.5 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 49/322 (15%), Positives = 106/322 (32%), Gaps = 38/322 (11%) Query: 99 IGGLAEFCKASAELALGENNEVLKSGRFVTV--QTIS-GTGALRVGASFLQRFFKFSRDV 155 + G+ + + + L + + + QT+ G + + + ++++ + V Sbjct: 55 MHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDSQTVVYGPSVIYMVSELIRQWSETGEGV 114 Query: 156 FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHN 215 + P++ + F G LE + PE ++LL N Sbjct: 115 VIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAKPECKIMLL-CSPQN 173 Query: 216 PTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQ 275 PTG ++ + +A + ++ + D + G+ W+ + + Sbjct: 174 PTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS--NVARGDWALLTSG 231 Query: 276 SYAKNM----GLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPP--LNGARIAAT 329 S + N+ G YG + +++ S LK R S+P A IAA Sbjct: 232 SKSFNIPALTGAYG--------IIENSSSRDAYLSALKG--RDGLSSPSVLALTAHIAAY 281 Query: 330 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPE 389 +P W + + + T + + NWQ Q + L+P Sbjct: 282 QQGAP-----W---LDALRIYLKDNLTYIADKMNAAFPELNWQ--IPQSTYLAWLDLRPL 331 Query: 390 QVER------LTKEFSVYMTKD 405 ++ L ++ V + Sbjct: 332 NIDDNALQKALIEQEKVAIMPG 353 >3G0T-A nrPDB Length = 437 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 35/208 (16%), Positives = 65/208 (31%), Gaps = 15/208 (7%) Query: 96 YLPIGGLAEFCKAS---AELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 Y + GL E + + A+L + + V T+ V R K Sbjct: 78 YPNLDGLPELKQEASRFAKLFVNIDIPAR-----ACVPTVGSMQGCFVSFLVANRTHKNR 132 Query: 153 R-DVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHA 211 P + + R G + + + ++ G LE + + ++ Sbjct: 133 EYGTLFIDPGFNLNKLQCRILGQKFESFDLFEY--RGEKLREKLESYLQTGQFCSIIYSN 190 Query: 212 CAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRH---FIEQG 268 +NPT E+ + I + K ++ D+AY G + Sbjct: 191 -PNNPTWQCMTDEELRIIGELATKHDVIVIEDLAYFGMDFRKDYSHPGEPLYQPSVANYT 249 Query: 269 INVCLCQSYAKNMGLYGERVGAFTVVCK 296 N L S +K G+R+G + K Sbjct: 250 DNYILALSSSKAFSYAGQRIGVLMISGK 277 >3GET-A nrPDB Length = 365 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 52/327 (15%), Positives = 101/327 (30%), Gaps = 36/327 (11%) Query: 97 LPIGGLAEFCKASAELALGENNEVLKSGRFVT----VQT---ISGTGALRVGASFLQRFF 149 P + + + + L ++ +++ + VQ I G G+ +V + Sbjct: 44 TPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSDQVIEFAIHSKL 103 Query: 150 KFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLL 209 ++ + + G + Y ++ + + ++ L+ Sbjct: 104 NSKNAFLQAGVTFAMYEIYAKQCGAKC-----YKTQSITHNLDEFKKLYETHKDEIKLIF 158 Query: 210 HACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGI 269 +NP G + E V + L D AY FAS K I++ Sbjct: 159 LCLPNNPLGECLDASEATEFIKGVNEDCLVVI-DAAYNEFASFKDSKKHLEPCELIKEFD 217 Query: 270 NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAAT 329 NV +++K GL G R+G +A K+ SN L A A Sbjct: 218 NVLYLGTFSKLYGLGGLRIG---YGIANANIISAFY---KLRAPFNVSNLALKAA--VAA 269 Query: 330 ILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMF----CFTG 385 + K M +L K+ + T+ I F T Sbjct: 270 MDDDEFTEKTLENNFSQM---------ELYKEFAKKHNIKIIDSYTNFITYFFDEKNSTD 320 Query: 386 LKPEQVER--LTKEFSVYMTKDGRISV 410 L + +++ + + Y RI++ Sbjct: 321 LSEKLLKKGIIIRNLKSYGLNAIRITI 347 >3EUC-A nrPDB Length = 367 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 57/287 (19%), Positives = 103/287 (35%), Gaps = 34/287 (11%) Query: 80 VRKAEAQIAAKNLDKEY-LPIGGLAEFCKASAELALG----ENNEVLKSGRFVTVQTISG 134 V + + ++ Y LP +E E+AL ++E L++ +Q +G Sbjct: 26 VPDSHGLVKLDAMENPYRLPPALRSELAARLGEVALNRYPVPSSEALRAKLKEVMQVPAG 85 Query: 135 ------TGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCG 188 G+ + + + V P P + + + AG++ G T Sbjct: 86 MEVLLGNGSDEIISMLALAAARPGAKVMAPVPGFVMYAMSAQFAGLEFVGVPLRADFT-- 143 Query: 189 FDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKK--NLFAFFDMAY 246 D L +++ V L A +NPTG + I + D AY Sbjct: 144 LDRGAMLAAMAEHQPAIVYL--AYPNNPTGNLFDAADMEAIVRAAQGSVCRSLVVVDEAY 201 Query: 247 QGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVES 306 Q FA +++W R N+ + ++ +K +GL G R+G V D + Sbjct: 202 QPFA-----QESWMSRL--TDFGNLLVMRTVSK-LGLAGIRLG---YVAGDP----QWLE 246 Query: 307 QLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIIS 353 QL +RP Y+ L A + L +Q +++ R+ Sbjct: 247 QLDK-VRPPYNVNVLTEATALFALEHVAVLDEQ-AAQLRAERSRVAE 291 >3LY1-A nrPDB Length = 354 Score = 55.1 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 35/160 (21%), Positives = 65/160 (40%), Gaps = 11/160 (6%) Query: 131 TISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFD 190 T + +R + ++ + + +P+ ++G+ + AGM++ + D FD Sbjct: 74 TAGSSEGIR---AAIEAYASLEAQLVIPELTYGDGEHFAKIAGMKVTKVKMLD--NWAFD 128 Query: 191 FSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFA 250 G ++ S++ L +NPTG P E K N D AY F Sbjct: 129 IEGLKAAVAAYSGPSIVYLVN-PNNPTG-TITPADVIEPWIASKPANTMFIVDEAYAEFV 186 Query: 251 SGDGDKDAWAVRHFIEQGIN-VCLCQSYAKNMGLYGERVG 289 + D ++ I QG + L ++++K + G RVG Sbjct: 187 N---DPRFRSISPMITQGAENIILLKTFSKIHAMAGMRVG 223 >4RAE-A nrPDB Length = 394 Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 57/354 (16%), Positives = 107/354 (30%), Gaps = 39/354 (11%) Query: 69 DDNGKPY-------VLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVL 121 ++N P V+ SVR+A + LA + A + LG N Sbjct: 40 NENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWA 99 Query: 122 KSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRY 181 + G+ + LQ F R PS+ H I + Sbjct: 100 AN------------GSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDG------THTE 141 Query: 182 YDPKTCGFDFSGALEDISKIPEQSV--LLLHACAHNPTGVDPRPEQWKEIASVVKKKNLF 239 + + DF ++ ++ A +NP+G ++ V Sbjct: 142 WIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVA---PGI 198 Query: 240 AFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCK--D 297 A D AY F+S AV E + + ++ +K G R+G D Sbjct: 199 AIVDEAYGEFSS-----QPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVID 253 Query: 298 AEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQ 357 A R+ L + + + +++ R++ + M R+I Sbjct: 254 AMLLVRLPYHLSSVTQAAARAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDAN 313 Query: 358 LVSNLKKEGSSHNWQHITDQIGMFCFTGLKP--EQVERLTKEFSVYMTKDGRIS 409 V + + W+ + + G+ L +E ++ RI+ Sbjct: 314 FVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIA 367 >3L8A-A nrPDB Length = 421 Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 40/207 (19%), Positives = 64/207 (30%), Gaps = 16/207 (7%) Query: 144 FLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRY-YDPKTCGFDFSGALEDISKIP 202 LQ F + V + P + R +L DF +DI I Sbjct: 135 ALQAFSEKGDAVLINSPVYYPFARTIRLNDHRLVENSLQIINGRFEIDFEQLEKDI--ID 192 Query: 203 EQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVR 262 + L HNP G + +IA + KK + D +Q A G+ Sbjct: 193 NNVKIYLLCSPHNPGGRVWDNDDLIKIAELCKKHGVILVSDEIHQDLALF-GNTHHSLNT 251 Query: 263 HFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLN 322 + S K + G + + E+ R + Q + L + P Sbjct: 252 LDASYKDFTIILSSATKTFNIAGTKNSFAII----QNESLRRKFQYRQLANNQHEVP--- 304 Query: 323 GARIAATILTSPDLR--KQWLQEVKGM 347 I T + K WL+E+K + Sbjct: 305 ---TVGMIATQAAFQYGKPWLEELKTV 328 >3FTB-A nrPDB Length = 361 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 38/243 (15%), Positives = 92/243 (37%), Gaps = 23/243 (9%) Query: 72 GKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKS----GRFV 127 G Y + E + N++ +P L + L + + + ++ Sbjct: 15 GDIYTEGVFKGRELLDYSSNINPLGIPKSFLNNIDEGIKNLGVYPDVNYRRLNKSIENYL 74 Query: 128 TVQTIS---GTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDP 184 ++ I G GA + + F + + PS+ + + G+ + + Y D Sbjct: 75 KLKDIGIVLGNGASEIIELSISLF----EKILIIVPSYAEYEINAKKHGVSVV-FSYLD- 128 Query: 185 KTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDM 244 + D+ + I + SV++ + +NP G E++ + + ++K D Sbjct: 129 ENMCIDYEDIISKIDDV--DSVIIGN--PNNPNGGLINKEKFIHVLKLAEEKKKTIIIDE 184 Query: 245 AYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRV 304 A+ F +GD ++ I+ + + ++ K + G R G + + E A ++ Sbjct: 185 AFIEF-TGD-PSSSFVGE--IKNYSCLFIIRAMTKFFAMPGIRFG--YGITNNKEIAAKI 238 Query: 305 ESQ 307 +++ Sbjct: 239 KAK 241 >3B1C-A nrPDB Length = 392 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 43/143 (30%), Gaps = 4/143 (2%) Query: 144 FLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPK-TCGFDFSGALEDISKIP 202 +Q F K V + P + R +L + DF DI + Sbjct: 105 AIQAFTKEGEAVLINSPVYPPFARSVRLNNRKLVSNSLKEENGLFQIDFEQLENDI--VE 162 Query: 203 EQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVR 262 L L HNP G E ++I + +K ++ D +Q G + Sbjct: 163 NDVKLYLLCNPHNPGGRVWEREVLEQIGHLCQKHHVILVSDEIHQDLTLF-GHEHVSFNT 221 Query: 263 HFIEQGINVCLCQSYAKNMGLYG 285 + + S K + G Sbjct: 222 VSPDFKDFALVLSSATKTFNIAG 244 >3T32-A nrPDB Length = 383 Score = 51.6 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 29/172 (16%), Positives = 56/172 (32%), Gaps = 7/172 (4%) Query: 136 GALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPK-TCGFDFSGA 194 G + ++ +Q F K + V + P + + QL T DF Sbjct: 90 GIVPALSTSIQAFTKENESVLVQPPIYPPFFEMVTTNNRQLCVSPLQKQNDTYAIDFEHL 149 Query: 195 LEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDG 254 + + L+L HNP G + E+ ++ S+ K N+ D + D Sbjct: 150 EKQFQ---QGVKLMLLCSPHNPIGRVWKKEELTKLGSLCTKYNVIVVADEIHSDIIYAD- 205 Query: 255 DKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVES 306 E C + +K + G + A ++ + + + S Sbjct: 206 HTHTPFASLSEELAARTITCMAPSKTFNIAGLQ--ASIIIIPNEKLRQAFTS 255 >1C7O-A nrPDB Length = 399 Score = 50.8 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 41/237 (17%), Positives = 79/237 (33%), Gaps = 32/237 (13%) Query: 87 IAAKNLDKEYLPIGGLAEFCKASAELALGENNEV-------LKSGRFVTVQT---ISGTG 136 +A I GL ++ + G E +K +QT I+ G Sbjct: 38 VADMEFKNPPELIEGLKKYLDETVLGYTGPTEEYKKTVKKWMKDRHQWDIQTDWIINTAG 97 Query: 137 ALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYD-PKTCGFDFSGAL 195 + + ++ F K V + P + ++ ++ + DF L Sbjct: 98 VVPAVFNAVREFTKPGDGVIIITPVYYPFFMAIKNQERKIIECELLEKDGYYTIDFQ-KL 156 Query: 196 EDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMA--------YQ 247 E +SK LL HNP G + ++ ++I +V K +L + D Y+ Sbjct: 157 EKLSKDKNNKA-LLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFDLIMPGYE 215 Query: 248 GFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRV 304 D+ ++ I S K + G +G ++ K+ + +R Sbjct: 216 HTVFQSIDEQ------LADKTI-TFTAPS--KTFNIAG--MGMSNIIIKNPDIRERF 261 >4DQ6-A nrPDB Length = 391 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 21/153 (13%), Positives = 47/153 (30%), Gaps = 7/153 (4%) Query: 135 TGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGA 194 G + + + K + + + +P + + ++ +L + + Sbjct: 97 PGVIPAISLLINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMD-- 154 Query: 195 LEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDG 254 EDI + L + HNP G ++ K++ + K N+ D + Sbjct: 155 YEDIENKIKDVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDI---IL 211 Query: 255 DKDAWAVRHFIEQGIN--VCLCQSYAKNMGLYG 285 K I + C + K + G Sbjct: 212 KKHKHIPMASISKEFEKNTITCMAPTKTFNIAG 244 >6HNB-A nrPDB Length = 491 Score = 48.1 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 54/370 (14%), Positives = 108/370 (29%), Gaps = 39/370 (10%) Query: 49 EAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK---NLDKEYLPIGGLAEF 105 E D + + G+GA + K + +KA + + +Y GL EF Sbjct: 56 EKVTADIPTPSFSGGIGAPIEGENKTTI-EVFKKAADNVPDQIELARSLQYGSTFGLPEF 114 Query: 106 CKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNH 165 + E + + + + ++ T A S L+ F + + + ++ + Sbjct: 115 LQFIKEHT--DMVHKVPYENWDVIVSVGNTEA---WDSTLRTFCSKGDTILVEEYTFSSA 169 Query: 166 TPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHAC-AHNPTGVDPRPE 224 G+ + + + + L C NPTG E Sbjct: 170 LESANGQGVNTVPVTMDEFGIIPEKLEELMS--RWVGNKPKFLYTICTGQNPTGSSLSAE 227 Query: 225 QWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWA------------VRHFIEQGI--- 269 + K+I + K + D Y KD A ++ + I Sbjct: 228 RRKQIYDIACKYDFLIIEDEPYYFLQMETYTKDKAAREGKAVHDHDEFLKALVPSFISLD 287 Query: 270 ---NVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARI 326 V S++K + G R+G + +R ++ ++ P + Sbjct: 288 VEGRVVRLDSFSKVL-APGLRLGWIVG---QKDLLERYVRLHEVSVQN-----PSGFSEA 338 Query: 327 AATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGL 386 A L +L + G+ R + L + GMF L Sbjct: 339 LANALLRKWGHSGYLDWLIGLRAEYTHKRDVAIDALDQFVPKEVSSFNPPVAGMFFTVTL 398 Query: 387 KPEQVERLTK 396 + + + Sbjct: 399 DASKHPKYKE 408 >4M2J-A nrPDB Length = 406 Score = 48.1 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 46/156 (29%), Gaps = 12/156 (7%) Query: 136 GALRVGASFLQRFFKFSRDVFLPKPSWG--NHTPIFRDAGMQLQGYRYYDPKTCGFDFSG 193 G+ A L V + + + H P R AG + + D Sbjct: 110 GSSEAIALTLNALLHRGDRVVVQEGIYHSLGHYP--RAAGCDVAVLPGRAVRDGEIDPDV 167 Query: 194 ALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGD 253 + + ++ HNPTGV P+ + + +D A A Sbjct: 168 LA---GLVTPGTAAVIVNFPHNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIAH-- 222 Query: 254 GDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 289 + G + + +K GL G RVG Sbjct: 223 ---RWEVLADPGADGGDTVSYGTLSKTFGLPGLRVG 255 >5Z0Q-C nrPDB Length = 389 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 38/114 (33%), Gaps = 2/114 (1%) Query: 199 SKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDA 258 ++ LLL HNP G R ++ + ++ +L D + G + Sbjct: 160 DRMSGNEKLLLLCNPHNPGGTVYRRKELEAQLRFAQRHDLLVCSDEIHCDLVLEPGVQHI 219 Query: 259 WAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILI 312 + S +K+ + G +GA V + E R K ++ Sbjct: 220 PFASLSDDAAQRSITLMSPSKSFNIAG--LGASLAVIPNPELRARFNRMRKGMV 271 >3G7Q-A nrPDB Length = 417 Score = 45.4 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 10/100 (10%) Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVC 272 NPTG E+ ++ + + N+ D AY G +A + N+ Sbjct: 189 PTNPTGNVITDEELMKLDRLANQHNIPLVIDNAYGVPFPGIIFSEARPL-----WNPNII 243 Query: 273 LCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILI 312 LC S +K +GL G R G ++ D + + +I Sbjct: 244 LCMSLSK-LGLPGSRCG--IIIANDKTITAI--ANMNGII 278 >3FDB-A nrPDB Length = 377 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 36/101 (35%), Gaps = 7/101 (6%) Query: 144 FLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPE 203 + F V +P P++ + + + T G + +E + Sbjct: 97 AIDHFTPAQSKVIVPTPAYPPFFHLLSATQRE----GIFIDATGGINLHD-VEKGFQAGA 151 Query: 204 QSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDM 244 +S+LL + +NP G+ PE E+ + + + D Sbjct: 152 RSILLCN--PYNPLGMVFAPEWLNELCDLAHRYDARVLVDE 190 >1LC8-A nrPDB Length = 364 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 67/180 (37%), Gaps = 15/180 (8%) Query: 129 VQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCG 188 + T ++ AS L+ R + P + + +G +++ R+ + G Sbjct: 80 LAGNGETESIFTVASGLKP-----RRAMIVTPGFAEYGRALAQSGCEIR--RWSLREADG 132 Query: 189 FDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQG 248 + + A+ + + L +NPTG+ P + IA K N+ D A+ Sbjct: 133 WQLTDAI--LEALTPDLDCLFLCTPNNPTGLLPERPLLQAIADRCKSLNINLILDEAFID 190 Query: 249 FASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQL 308 F + + + ++ + +S K + G R+G V DA A+ Q+ Sbjct: 191 F----IPHETGFIPALKD-NPHIWVLRSLTKFYAIPGLRLGYL-VNSDDAAMARMRRQQM 244 >3P1T-A nrPDB Length = 337 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 208 LLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQ 267 ++ A NPTG + + ++++ D Y D ++ R Sbjct: 139 VVLANPSNPTGQALSAGELDQ----LRQRAGKLLIDETY-------VDYSSFRARGLA-Y 186 Query: 268 GINVCLCQSYAKNMGLYGERVGAF 291 G N + +S++K+ GL G R+GA Sbjct: 187 GENELVFRSFSKSYGLAGLRLGAL 210 >5DJ3-A nrPDB Length = 376 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 56/158 (35%), Gaps = 15/158 (9%) Query: 93 DKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFS 152 + E P+ + + LG++ + GR ++ + S V L R S Sbjct: 51 ESEQRPVQQIESEAHQAYFTLLGQHGYPAEPGRVLSCYSSS------VSMEILARSLSAS 104 Query: 153 -RDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHA 211 V L P++ N + R G+ L + G D S L V + Sbjct: 105 VDRVALVHPTFDNIADLLRGNGLDLV--PVEEDALHGADLSAEL----LSSVGCVFV--T 156 Query: 212 CAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGF 249 +NPTG E+ + +A + D +++GF Sbjct: 157 TPNNPTGRVLAEERLRRLAEQCAEHGTVLALDTSFRGF 194 >6C3C-A nrPDB Length = 413 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 35/257 (13%), Positives = 79/257 (30%), Gaps = 23/257 (8%) Query: 155 VFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAH 214 V L +P + N + + + L Y ++ +D ++ + L L + Sbjct: 132 VTLIEPCFDNLYDVLANMDVPL--YPI--DESVFYDVDRIYPELERRVRTDALFLVD-PN 186 Query: 215 NPTGVDP---RPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQ-GIN 270 NPTG + ++E+ K + D + F + + + + +E G+ Sbjct: 187 NPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVR 246 Query: 271 VCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATI 330 + K + + ++ + + V + L + S LN Sbjct: 247 YLAIEDTGKT---WPVQDAKCALITASDDIWETVYN-LHTSVLLNVSPFVLN-------- 294 Query: 331 LTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMF--CFTGLKP 388 + + +R + + + + R L + + + F L Sbjct: 295 MLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTA 354 Query: 389 EQVERLTKEFSVYMTKD 405 V RL VY+ Sbjct: 355 TDVHRLLSADGVYVLPG 371 >5IWQ-A nrPDB Length = 434 Score = 36.6 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 56/333 (16%), Positives = 101/333 (30%), Gaps = 44/333 (13%) Query: 94 KEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQ--RFFKF 151 + Y + G+ + + A+L +VL +L + + F Sbjct: 71 RNYGGLDGIVDIRQIWADLLGVPVEQVLA----------GDASSLNIMFDVISWSYIFGN 120 Query: 152 SRDV-----------FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISK 200 + V P P + H I G ++ G D A+E++ K Sbjct: 121 NDSVQPWSKEETVKWICPVPGYDRHFSITERFGFEMISVPM---NEDGPDMD-AVEELVK 176 Query: 201 IPEQSVLLLHACAHNPTGVDPRPEQWKEIASV-VKKKNLFAFFDMAYQGFASGDGDKDAW 259 P+ + + NPTG + K ++++ + +D AY D + Sbjct: 177 NPQVKGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTDEFPEVI 236 Query: 260 AVRHFIEQ--GINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYS 317 + E N + + L G + AE K IR + Sbjct: 237 DIVGLGEAAGNPNRFWAFTSTSKITLAG---AGVSFFLTSAENRKWYTGH--AGIRGIGP 291 Query: 318 NPPLNGARIAATILTSPD-LRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITD 376 N A A + +R + +A + + L S L + G + W Sbjct: 292 NKVNQLAH--ARYFGDAEGVRAVMRKHAASLAPKFNKVLEILDSRLAEYGVA-QWT--VP 346 Query: 377 QIGMFCFTGL---KPEQVERLTKEFSVYMTKDG 406 G F + +V L KE + +T G Sbjct: 347 AGGYFISLDVVPGTASRVAELAKEAGIALTGAG 379 >5HDM-A nrPDB Length = 434 Score = 35.8 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 80/249 (32%), Gaps = 39/249 (15%) Query: 49 EAFKRDTN--SKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGG----- 101 EAF N +N V A++ G+P ++ SV+ ++ N +Y+ G Sbjct: 15 EAFNAAKNLMPGGVNSPVRAFKSVGGQPVLIDSVKGSKMWDIDGNEYIDYVGSWGPAIIG 74 Query: 102 ------LAEFCKASAE-LALGENNE---VLKSGRFVTVQTI-------SGTGALRVGASF 144 LA + + + G VL V +I SGT A +G Sbjct: 75 HADDEVLAALAETMKKGTSFGAPCLLENVLAEMVISAVPSIEMVRFVNSGTEAC-MGVLR 133 Query: 145 LQRFFKFSRDVFLPKPSWGNHTPIF-RDAGMQLQGY-----------RYYDPKTCGFDFS 192 L R F + + H F AG + D T ++ Sbjct: 134 LARAFTNKEKFIKFEGCYHGHANAFLVKAGSGVATLGLPDSPGVPKAATSDTLTAPYNDL 193 Query: 193 GALEDISKIPEQ--SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFA 250 A+E + + S ++L N + P PE + + K + FD GF Sbjct: 194 EAVEKLFAAHKGEISAVILEPVVGNSGFIPPTPEFINGLRQLTKDNGVLLIFDEVMTGFR 253 Query: 251 SGDGDKDAW 259 G + Sbjct: 254 LAYGGAQEY 262 >4JE5-A nrPDB Length = 503 Score = 35.0 bits (79), Expect = 0.056, Method: Composition-based stats. Identities = 46/284 (16%), Positives = 87/284 (30%), Gaps = 35/284 (12%) Query: 121 LKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYR 180 LK + + T T A S L+ F + + S+ + G+ Sbjct: 131 LKYKDWDVLATAGNTNA---WESTLRVFCNRGDVILVEAHSFSSSLASAEAQGVITFPVP 187 Query: 181 YYDPKTCGFDFSGALEDIS-KIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLF 239 + +E+ + P+ +L NPTG + + I + +K + Sbjct: 188 IDADGIIPEKLAKVMENWTPGAPKPKLLYTIPTGQNPTGTSIADHRKEAIYKIAQKYDFL 247 Query: 240 AFFDMAYQGFASG-------DGDKDAWAVRHFIEQGI--------------NVCLCQSYA 278 D Y + +K + + ++ + V S++ Sbjct: 248 IVEDEPYYFLQMNPYIKDLKEREKAQSSPKQDHDEFLKSLANTFLSLDTEGRVIRMDSFS 307 Query: 279 KNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRK 338 K + G R+G T K K S ++ I+ P + L+ +K Sbjct: 308 KVL-APGTRLGWITGSSK---ILKPYLSLHEMTIQA----PAGFTQVLVNATLSRWG-QK 358 Query: 339 QWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQI-GMF 381 +L + G+ R + L K + I I GMF Sbjct: 359 GYLDWLLGLRHEYTLKRDCAIDALYKYLPQSDAFVINPPIAGMF 402 >2Z0F-A nrPDB Length = 524 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 39/117 (33%), Gaps = 11/117 (9%) Query: 101 GLAEFCKASAELALGENNEVLKSGRFVTVQ-TISGTGALRVGASFLQRFFKFSRDVFLPK 159 G + +S + E + + + ++ + TG F L + Sbjct: 27 GTSGHRGSSLKATFTEAHVLAIAQAIAELRPSFGATG----------PLFLAKDTHALSE 76 Query: 160 PSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNP 216 P+W +F G++++ D LE + ++ +L +HNP Sbjct: 77 PAWATALSVFAAHGIEVRVEADGDYTPTPLVSLAILEHNAHHEAKADGVLLTPSHNP 133 >5VC2-A nrPDB Length = 424 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 64/375 (17%), Positives = 104/375 (27%), Gaps = 65/375 (17%) Query: 13 MAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNG 72 MA H +A S + + F+ N + +N Sbjct: 1 MAHHHHHHMAYFLEQTDSEIFELI--------------FEEYKRQ---NEHLEMIASEN- 42 Query: 73 KPYVLPSVRKAEAQIAAKNLDKEYLPIG--GLAEFCKASAELALGENNEVLKSGRFVTVQ 130 Y PSV +A I + Y G E LA+ ++ F VQ Sbjct: 43 --YTFPSVMEAMGSILTNKYAEGYPNKRYYGGCEVVDKIESLAIERAKKLFNCQ-FANVQ 99 Query: 131 TISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHT---PIFRDAGMQLQGYRYYDPKTC 187 SG+ A + K + S G H G Q + Y Sbjct: 100 AHSGSQA---NNAVYHALLKPYDKILGMDLSCGGHLTHGAKVSLTGKHYQSFSYGVNLDG 156 Query: 188 GFDFSGALEDISKIPEQSVLLLHACAHNPTGVD--PRPEQWKEIASVVKKKNLFAFFDMA 245 D+ AL+ + + ++ G PR +K+ + + D+A Sbjct: 157 YIDYEEALKIAQSVKPEIIV---------CGFSAYPREIDFKKFREIADEVGALLLGDIA 207 Query: 246 YQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVE 305 + V + C S + L G R G ++ D E A +++ Sbjct: 208 HVA---------GLVVTNEHAHPFPHCHVVSSTTHKTLRGPRGG--IILTNDEEIAAKID 256 Query: 306 SQLKILIRPLYSNPPLNGARIAATILTSP-DLRKQWLQEVKGMADRIISMRTQLVSNLK- 363 + P G + I ++ E K A + S L LK Sbjct: 257 KAI---------FPGTQGGPLMHVIAAKAVGFKENLKPEFKAYAKLVKSNMQVLAKALKE 307 Query: 364 ---KEGSSHNWQHIT 375 K S H+ Sbjct: 308 KNHKLVSGGTSNHLL 322 >5KR5-A nrPDB Length = 479 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 41/119 (34%), Gaps = 15/119 (12%) Query: 135 TGALRVGASFLQRFFKFSRDV-FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSG 193 TG+L SF Q F V P W N P +A Q Y Sbjct: 180 TGSLTGLPSFHQHFDLPIDRVKHTVCPHWYNAPPGMSEA--QFVAYCV----------EE 227 Query: 194 ALEDISKIPEQSVLLLHACAHNPTG--VDPRPEQWKEIASVVKKKNLFAFFDMAYQGFA 250 + I++ ++ A TG V P W+ I +V++K ++ D GF Sbjct: 228 LEKLIAREGADTIAAFIAEPVMGTGGIVPPPQGYWEAIQAVLRKHDILLIADEVVCGFG 286 >3FKD-A nrPDB Length = 350 Score = 33.1 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 33/181 (18%), Positives = 60/181 (33%), Gaps = 29/181 (16%) Query: 127 VTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKT 186 + T T A A + + PS+ + R ++ Y + Sbjct: 69 AILVTNGPTAAFYQIAQAFR-----GSRSLIAIPSFAEYEDACRMYEHEVCFYPS-NEDI 122 Query: 187 CGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFF-DMA 245 DFS L + +NP G Q EI ++ F D + Sbjct: 123 GEADFSNM---------DFCWLCN--PNNPDGRLL---QRTEILRLLNDHPDTTFVLDQS 168 Query: 246 YQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVE 305 Y F + + + A I+ N+ + S++ G+ G R+G + + + KRV Sbjct: 169 YVSFTTEEVIRPAD-----IKGRKNLVMVYSFSHAYGIPGLRIG---YIVANKDFMKRVA 220 Query: 306 S 306 + Sbjct: 221 A 221 >2W21-A nrPDB Length = 259 Score = 32.3 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 24/157 (15%), Positives = 49/157 (31%), Gaps = 23/157 (14%) Query: 247 QGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVES 306 + + + + G L Q + + +YG VG + D E+ +R + Sbjct: 58 EHLGYPELPATIASKQLLAAVG-QSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLN 116 Query: 307 QLKILIRPLYSN---PPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLK 363 L R L N P +N A + +++ + +A Sbjct: 117 ARDTL-RALLDNNVVPVINENDAVA----TAEIKVGDNDNLSALAA-------------- 157 Query: 364 KEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSV 400 + +TDQ G++ Q E + + + Sbjct: 158 ILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGI 194 >2J5V-A nrPDB Length = 367 Score = 32.3 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 24/157 (15%), Positives = 49/157 (31%), Gaps = 23/157 (14%) Query: 247 QGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVES 306 + + + + G L Q + + +YG VG + D E+ +R + Sbjct: 58 EHLGYPELPATIASKQLLAAVG-QSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLN 116 Query: 307 QLKILIRPLYSN---PPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLK 363 L R L N P +N A + +++ + +A Sbjct: 117 ARDTL-RALLDNNVVPVINENDAVA----TAEIKVGDNDNLSALAA-------------- 157 Query: 364 KEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSV 400 + +TDQ G++ Q E + + + Sbjct: 158 ILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGI 194 >4RY2-A nrPDB Length = 730 Score = 31.6 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 45/158 (28%), Gaps = 16/158 (10%) Query: 104 EFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWG 163 +F + L N + G+ V + SG+G + + + D+ + S Sbjct: 495 DFRYGLRKPVLKNINLTIPKGKTVAIVGESGSGKTTLAKLLMNFYSPEKGDILINGHSIK 554 Query: 164 N--HTPIFRDAGMQLQGYRYYDPK--------TCGFDFSGALEDISKIPEQSVL----LL 209 N I + Q + D ++ + L Sbjct: 555 NISLELIRKKIAFVSQDVFIFSGTVKENLCLGNENVDMDEIIKAAKMANAHDFIEKLPLK 614 Query: 210 HACAHNPTGVDPRPEQWK--EIASVVKKKNLFAFFDMA 245 + N +G + Q + IA + KK D A Sbjct: 615 YDTFLNESGANLSEGQKQRLAIARALLKKPDILILDEA 652 >4E16-A nrPDB Length = 253 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 326 IAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTG 385 I A L +P+L ++ +E + + +++ +++ G +N + Q G F G Sbjct: 35 IYAGSLVNPELL-EYCKEDCQIHNSAHMDLQEIIDVMRE-GIENNKSVVRLQTGDFSIYG 92 Query: 386 LKPEQVERLTK 396 EQVE L K Sbjct: 93 SIREQVEDLNK 103 >3TBG-A nrPDB Length = 479 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 37/99 (37%), Gaps = 6/99 (6%) Query: 77 LPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTG 136 L +VR+A D+ +PI + F S + L + R +V T+ G Sbjct: 62 LAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLG 121 Query: 137 ALRVGASFLQRFFKFSRDVFLPKPSWGNHTPI-FRDAGM 174 +G L+++ + NH+ FR G+ Sbjct: 122 ---LGKKSLEQWVTEEAACLCAA--FANHSGRPFRPNGL 155 >3GJU-A nrPDB Length = 460 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 41/119 (34%), Gaps = 14/119 (11%) Query: 135 TGALRVGASFLQRFFK-FSRDVF-LPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFS 192 TG+L G F V P + FR + ++ + C Sbjct: 161 TGSLT-GLDLFHNAFDLPRAPVLHTEAPYY------FRRTDRSMSEEQF--SQHCADKLE 211 Query: 193 GALEDISKIPEQSVLLLHACAHNPTGVDPRPE-QWKEIASVVKKKNLFAFFDMAYQGFA 250 + +++ PE + G+ P P W++I +V+KK ++ D GF Sbjct: 212 EMI--LAEGPETIAAFIGEPILGTGGIVPPPAGYWEKIQAVLKKYDVLLVADEVVTGFG 268 >3NCO-A nrPDB Length = 320 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 49/149 (32%), Gaps = 23/149 (15%) Query: 147 RFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSV 206 R SR V + P+W N++ + + + D K F E + + + Sbjct: 166 RKTNPSRIVIIDVPNWSNYSYV--------RELKLVDDKNIIVSFH-YYEPFNFTHQGAE 216 Query: 207 LLLHACAHNPTGVDPRPEQW--KEIASVVK------KKNLFAFFDMAYQGFASGDGDKDA 258 + P GV + W ++I + K KKN F + ++ D + Sbjct: 217 WV---SPTLPIGVKWEGKDWEVEQIRNHFKYVSEWAKKNNVPIFLGEFGAYSKADMESRV 273 Query: 259 ---WAVRHFIEQGINVCLCQSYAKNMGLY 284 VR E+ + GLY Sbjct: 274 KWTKTVRRIAEEFGFSLAYWEFCAGFGLY 302 >6IO1-A nrPDB Length = 451 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 14/32 (43%) Query: 219 VDPRPEQWKEIASVVKKKNLFAFFDMAYQGFA 250 V P W IA+V++K + D GF Sbjct: 236 VVPPDGYWPAIAAVLRKYGILLILDEVITGFG 267 >5KR3-A nrPDB Length = 479 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 39/119 (32%), Gaps = 15/119 (12%) Query: 135 TGALRVGASFLQRFFKFSRDV-FLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSG 193 TG+L SF Q F V P W + + Q Y Sbjct: 180 TGSLTGLPSFHQHFDLPIDRVKHTVCPHW--YRAPAGMSEAQFVAYCV----------EE 227 Query: 194 ALEDISKIPEQSVLLLHACAHNPTG--VDPRPEQWKEIASVVKKKNLFAFFDMAYQGFA 250 + I++ ++ A TG + P W+ I +V++K ++ D GF Sbjct: 228 LEKLIAREGADTIAAFIAEPVMGTGGIIPPPQGYWEAIQAVLRKHDILLIADEVVCGFG 286 >3WKR-A nrPDB Length = 416 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 41/104 (39%), Gaps = 15/104 (14%) Query: 338 KQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNW--------QHITD---QIGMFCFTGL 386 K+W +E+K + + L + H+ I + G F + L Sbjct: 314 KKWDEELKKTRYVVDELEKIGFKQLGIKPKEHDLIKFETPVLDEIAKKDKRRGFFFYDEL 373 Query: 387 KPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430 K + + +TK+ ++SV G+ V Y+ +AI ++ + Sbjct: 374 KKRGIGGIRAG----VTKEIKMSVYGLEWEQVEYVVNAIKEIVE 413 >4AR2-A nrPDB Length = 509 Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 19/52 (36%), Gaps = 5/52 (9%) Query: 205 SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDK 256 ++LL C GVD + + + K+ F + Y+ G+ Sbjct: 248 DIVLLPGC-----GVDFTESRLSNLLGIRKRHPFQEGFKIMYEDLEGGNIPA 294 >1SEZ-A nrPDB Length = 504 Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 15/39 (38%), Gaps = 4/39 (10%) Query: 363 KKEGSSHNWQHITDQIGMFCFTG----LKPEQVERLTKE 397 KK+G + Q G F F G L + L ++ Sbjct: 218 KKQGPPKTSANKKRQRGSFSFLGGMQTLTDAICKDLRED 256 >5TX1-N nrPDB Length = 497 Score = 29.6 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 23/63 (36%), Gaps = 5/63 (7%) Query: 205 SVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHF 264 V+LL C GVD + + + KK+ F + Y+ G+ ++ Sbjct: 210 DVVLLPGC-----GVDFTESRLSNLLGIRKKQPFQEGFRIMYEDLEGGNIPALLDVPKYL 264 Query: 265 IEQ 267 + Sbjct: 265 ESK 267 >5KR6-A nrPDB Length = 479 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 198 ISKIPEQSVLLLHACAHNPTGVDPRPE-QWKEIASVVKKKNLFAFFDMAYQGFA 250 +++ P+ + G+ P PE W+ I +V+ K ++ D GF Sbjct: 233 LAEGPDTVAAFIGEPVMGTGGIVPPPEGYWEAIQAVLNKYDILLIADEVVCGFG 286 >2BHU-A nrPDB Length = 602 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 21/56 (37%), Gaps = 3/56 (5%) Query: 213 AHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQG 268 + P G RPE + + L F D+ Y F ++A +F ++ Sbjct: 185 PYAPYG---RPEDLMALVDAAHRLGLGVFLDVVYNHFGPSGNYLSSYAPSYFTDRF 237 >3ULE-B nrPDB Length = 394 Score = 28.9 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 28/68 (41%), Gaps = 6/68 (8%) Query: 180 RYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLF 239 R +D +D++ E ++ +LL NPT + ++I V+ + F Sbjct: 80 RNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPT------KNREKIVEVMFETYQF 133 Query: 240 AFFDMAYQ 247 + +A Q Sbjct: 134 SGVYVAIQ 141 >5I92-A nrPDB Length = 435 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 74/449 (16%), Positives = 140/449 (31%), Gaps = 101/449 (22%) Query: 13 MAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKR-----------------DT 55 MA H ++ R+ + + + + P + AFK D Sbjct: 1 MAHHHHHHMS-----RSETLFNNAQKHIPGGVNSPVRAFKSVGGTPLFFKHAEGAYVLDE 55 Query: 56 NSKKMNLGVGAYRD---DNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAEL 112 + K+ VG++ + P VL +VR+ + +A+ + Sbjct: 56 DDKRYVDYVGSWGPMILGHSHPDVLDAVRR--QLDHGLSYGAPTALEVEMADLVCSMV-- 111 Query: 113 ALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHT-PIFRD 171 ++ R V+ SGT A + A L R + + + + H+ + Sbjct: 112 ------PSMEMVRMVS----SGTEA-TMSAIRLARGYTGRDSIIKFEGCYHGHSDSLLVK 160 Query: 172 AGMQLQGY---------RYYDPKTCGFDFSGALEDISKI-----PEQSVLLLHACAHNPT 217 AG + + T F+ +E + K E + +++ A N Sbjct: 161 AGSGALTFGVPNSPGVPAAFAKHTLTLPFND-IEAVRKTLGEVGKEVACIIVEPVAGNMN 219 Query: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277 V P P + + + + FD GF G A+ Sbjct: 220 CVPPAPGFLEGLREACDEHGVVLIFDEVMTGFRVALGGAQAY---------------YGV 264 Query: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGAR-IAATILTSPDL 336 ++ +G+ +G V + + + Q + P+Y L+G A LT+ L Sbjct: 265 TPDLSTFGKIIGGGMPVGAFGGKREIM--QQISPLGPVYQAGTLSGNPLAMAAGLTTLRL 322 Query: 337 --RKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQ-IGMF-----------C 382 R + E+ R++ L++ + +T Q GMF Sbjct: 323 ISRPGFHDELTAYTTRML-------DGLQQRADAAGIPFVTTQAGGMFGLYFSGADAIVT 375 Query: 383 FTGLKPEQVERLTKEFS------VYMTKD 405 F + VER + F VY+ Sbjct: 376 FEDVMASDVERFKRFFHLMLDGGVYLAPS 404 >6D8G-A nrPDB Length = 886 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 36/84 (42%) Query: 305 ESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKK 364 E L+ +IR Y++P + IL + + E+K + +R +++ +L LK+ Sbjct: 402 ERNLREMIRQHYNHPSIITWGYMNEILLVTQRKYKTEAELKPVLERTLALANRLERVLKE 461 Query: 365 EGSSHNWQHITDQIGMFCFTGLKP 388 E S+ + TGL Sbjct: 462 EDSTRISTMAFHGSNSYNETGLSK 485 >1WU5-A nrPDB Length = 396 Score = 27.7 bits (60), Expect = 9.9, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 36/112 (32%), Gaps = 15/112 (13%) Query: 135 TGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGA 194 T + G +++ + P P + + + +R+ D F++S Sbjct: 102 TEGVHAGYFAWSCQPDGTKNSWGPAPDGEEYFAL----ALFFASHRWGDGDEQPFNYSEQ 157 Query: 195 LEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAY 246 + LH C HN G P W ++K F D +Y Sbjct: 158 ARKL----------LHTCVHNGEG-GPGHPMWNRDNKLIKFIPEVEFSDPSY 198 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.134 0.354 Lambda K H 0.267 0.0412 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,423,351 Number of Sequences: 36641 Number of extensions: 668692 Number of successful extensions: 7571 Number of sequences better than 10.0: 241 Number of HSP's better than 10.0 without gapping: 161 Number of HSP's successfully gapped in prelim test: 122 Number of HSP's that attempted gapping in prelim test: 7123 Number of HSP's gapped (non-prelim): 315 length of query: 430 length of database: 10,336,785 effective HSP length: 100 effective length of query: 330 effective length of database: 6,672,685 effective search space: 2201986050 effective search space used: 2201986050 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.1 bits)