BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05198 (315 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6O9Z-L nrPDB 640 0.0 6FEC-P nrPDB 541 e-154 1KL9-A nrPDB 375 e-105 3JAQ-j nrPDB 313 9e-86 2A1A-A nrPDB 198 2e-51 3CW2-C nrPDB 80 1e-15 1YZ6-A nrPDB 77 1e-14 2K4K-A nrPDB 44 9e-05 6H58-y nrPDB 35 0.039 3CDI-A nrPDB 33 0.16 5YJJ-A nrPDB 33 0.21 1LUZ-A nrPDB 33 0.21 4NBQ-A nrPDB 32 0.25 2R5R-A nrPDB 31 0.80 1PT7-A nrPDB 30 1.4 1JCN-A nrPDB 30 1.6 5EOV-A nrPDB 29 2.5 3A9Z-A nrPDB 28 3.5 1E3H-A nrPDB 28 4.4 1XDU-A nrPDB 28 5.9 1YZ7-A nrPDB 27 7.8 >6O9Z-L nrPDB Length = 323 Score = 640 bits (1651), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/314 (100%), Positives = 314/314 (100%) Query: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK Sbjct: 10 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 69 Query: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY Sbjct: 70 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 129 Query: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 181 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN Sbjct: 130 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 189 Query: 182 RRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTT 241 RRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTT Sbjct: 190 RRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTT 249 Query: 242 LERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVD 301 LERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVD Sbjct: 250 LERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVD 309 Query: 302 GDDDAEEMEAKAED 315 GDDDAEEMEAKAED Sbjct: 310 GDDDAEEMEAKAED 323 >6FEC-P nrPDB Length = 266 Score = 541 bits (1395), Expect = e-154, Method: Compositional matrix adjust. Identities = 264/266 (99%), Positives = 265/266 (99%) Query: 6 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRI 65 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRI Sbjct: 1 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRI 60 Query: 66 GRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE 125 GRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE Sbjct: 61 GRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE 120 Query: 126 QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLT 185 QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLT Sbjct: 121 QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLT 180 Query: 186 PQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERT 245 PQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE MPIKINLIAPPRYVMTTTTLERT Sbjct: 181 PQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERT 240 Query: 246 EGLSVLSQAMAVIKEKIEEKRGVFNV 271 EGLSVL+QAMAVIKEKIEEKRGVFNV Sbjct: 241 EGLSVLNQAMAVIKEKIEEKRGVFNV 266 >1KL9-A nrPDB Length = 182 Score = 375 bits (964), Expect = e-105, Method: Compositional matrix adjust. Identities = 182/182 (100%), Positives = 182/182 (100%) Query: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK Sbjct: 1 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 60 Query: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY Sbjct: 61 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 120 Query: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 181 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN Sbjct: 121 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 180 Query: 182 RR 183 RR Sbjct: 181 RR 182 >3JAQ-j nrPDB Length = 304 Score = 313 bits (801), Expect = 9e-86, Method: Compositional matrix adjust. Identities = 160/298 (53%), Positives = 217/298 (72%), Gaps = 9/298 (3%) Query: 1 MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN 60 M CRFY++K+PE++D+VMVNV+ IAEMGAYV LLEY+NIEGMILLSELSRRRIRSI Sbjct: 1 MSTSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ 60 Query: 61 KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE 120 KLIR+G+N+ VV+RVDKEKGYIDLSKRRVS E+ IKCE+K+ KSKTV+SILR+ AE + Sbjct: 61 KLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQ 120 Query: 121 YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINN 179 LE L++ AW K+ AY+AFK ++ D ++ + ++ ++D + L N Sbjct: 121 IP----LEELYKTIAWPLSRKFGH----AYEAFKLSIIDETVWEGIEPPSKDVLDELKNY 172 Query: 180 INRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTT 239 I++RLTPQAVKIRAD+EV+C+ YEGIDA+K+AL++ + STE M +K+ L+A P YV+TT Sbjct: 173 ISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVKLVAAPLYVLTT 232 Query: 240 TTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLEREN 297 L++ +G+ L A+ I E I + GV N+ M PK VT T++ EL +E E +N Sbjct: 233 QALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQALLESKELDN 290 >2A1A-A nrPDB Length = 175 Score = 198 bits (504), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 103/179 (57%), Positives = 137/179 (76%), Gaps = 9/179 (5%) Query: 6 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRI 65 CRFY++K+PE++D+VMVNV+ IAEMGAYV LLEY+NIEGMILLSELSRRRIRSI KLIR+ Sbjct: 5 CRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRV 64 Query: 66 GRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE 125 G+N+ VV+RVDKEKGYIDLSKRRVS E+ IKCE+K+ KSKTV+SILR+ AE + Sbjct: 65 GKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIP--- 121 Query: 126 QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLD-LNEDEREVLINNINRR 183 LE L++ AW K+ AY+AFK ++ D ++ + ++ ++D + L N I++R Sbjct: 122 -LEELYKTIAWPLSRKFGH----AYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISKR 175 >3CW2-C nrPDB Length = 266 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 130/261 (49%), Gaps = 15/261 (5%) Query: 8 FYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGR 67 + + K P ++++ V+ + + G+YVSL EY ++ + SE+S + +++I +++ R Sbjct: 3 YSRSKLPSEGEILIATVKQVFDYGSYVSLDEYGGLQAFLPWSEVSSKWVKNIRDVLKENR 62 Query: 68 NECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQL 127 V VIRVD+ KG +D+S ++V+ +E K ++ K + + IL V++ L+ ++ + Sbjct: 63 KVIVKVIRVDRRKGTVDVSLKKVTDDERRKKNLQWKKIQRLDKILELVSQKLKLSEKDA- 121 Query: 128 ESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQ 187 +++ AW + KY P A K IL + E + L+ ++ + Sbjct: 122 ---WEQVAWKLEAKYGDPITAIEKAVKEG---EKILIDAGVPEIWVKPLLEEASKHAEER 175 Query: 188 AVKIRADIEVACYGYEGIDAVKEALRAGLNCSTEN----MPIKINLIAPPRY---VMTTT 240 VK+ I V G++ +KE + L ++ + IKI I PRY V+ T Sbjct: 176 KVKMSGLITVRTNEPLGVEKIKEVISKALENIEQDYESLLNIKIYTIGAPRYRVDVVGTN 235 Query: 241 TLERTEGLS-VLSQAMAVIKE 260 E +E L+ ++S + + KE Sbjct: 236 PKEASEALNQIISNLIKIGKE 256 >1YZ6-A nrPDB Length = 274 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 72/255 (28%), Positives = 126/255 (49%), Gaps = 16/255 (6%) Query: 13 FPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVV 72 +PE + V+ V+ I GA++ L EY E + +SE++ +R+I ++ G+ Sbjct: 7 YPEEGEFVVATVKRIHNYGAFLELDEYPGKEAFMHISEVASTWVRNIRDYLKEGQKVVAK 66 Query: 73 VIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQ 132 VIRVD KG+IDLS RRV+ ++ +F +++ ++L+ AE L KD E+ + Sbjct: 67 VIRVDPRKGHIDLSLRRVTQQQRKAKLQEFKRAQKAENLLKLAAEKL--GKD--FETAW- 121 Query: 133 RTAWV-FDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKI 191 R WV ++++ Y AF+ A D + + ++ VL I+ + V I Sbjct: 122 REVWVPLEEEWGE----VYAAFEDAAKDGIDVLKGHVPDEWLPVLKEIIDNYVEVPTVTI 177 Query: 192 RADIEVACYGYEGIDAVKEAL-RAGLNCSTE-NMPIKINLIAPPRYVMTTTTLERTEGLS 249 A+ E+ G++ +KEAL RA + E ++ +K + PRY + T + + Sbjct: 178 DAEFEITVPKPNGVEIIKEALIRARDRANKEKDVEVKFTYLGAPRYRIDITAPDYYKAEE 237 Query: 250 VL----SQAMAVIKE 260 VL + + VIKE Sbjct: 238 VLESIAEEILRVIKE 252 >2K4K-A nrPDB Length = 130 Score = 43.9 bits (102), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 4/82 (4%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 EV V V + GA+V+L E +G++ +SE++ ++ IN+ + +G V V+ Sbjct: 6 EVGSVYTGKVTGLQAYGAFVALDE--ETQGLVHISEVTHGFVKDINEHLSVGDEVQVKVL 63 Query: 75 RVDKEKGYIDLSKR--RVSPEE 94 VD+EKG I LS R + +PE+ Sbjct: 64 AVDEEKGKISLSIRATQAAPEK 85 >6H58-y nrPDB Length = 557 Score = 35.0 bits (79), Expect = 0.039, Method: Compositional matrix adjust. Identities = 13/79 (16%), Positives = 47/79 (59%), Gaps = 3/79 (3%) Query: 24 VRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYI 83 V+++ + GA+V L ++G++ +++++ +R++ ++++ +G V V++ D+E+ + Sbjct: 199 VKNLTDYGAFVDL---GGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRV 255 Query: 84 DLSKRRVSPEEAIKCEDKF 102 L +++ + + ++ Sbjct: 256 SLGLKQLGEDPWVAIAKRY 274 >3CDI-A nrPDB Length = 723 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 41/72 (56%), Gaps = 3/72 (4%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 EV V V I + GA+V++ EG++ +S+++ +R+ + +++G+ V V+ Sbjct: 626 EVGRVYTGKVTRIVDFGAFVAI--GGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVL 683 Query: 75 RVDKEKGYIDLS 86 VD++ G I LS Sbjct: 684 EVDRQ-GRIRLS 694 >5YJJ-A nrPDB Length = 713 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 41/74 (55%), Gaps = 3/74 (4%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 EV V V+ I + GA+V L + + ++ +S++S+ RI + +++IG V + Sbjct: 636 EVGQVYHAKVKRIEKYGAFVEL--FPGKDALLHISQISQERINKVEDVLKIGDTIEVKIT 693 Query: 75 RVDKEKGYIDLSKR 88 +DK+ G ++ S + Sbjct: 694 EIDKQ-GRVNASHK 706 >1LUZ-A nrPDB Length = 88 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 9/88 (10%) Query: 11 HKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSR----RRIRSINKLIRIG 66 + P DV+ V + Y+ L +Y + E +L+E + R + +KL+ G Sbjct: 6 YSLPNAGDVIKGRVYE-KDYALYIYLFDYPHFEA--ILAESVKMHMDRYVEYRDKLV--G 60 Query: 67 RNECVVVIRVDKEKGYIDLSKRRVSPEE 94 + V VIRVD KGYID++ +R+ + Sbjct: 61 KTVKVKVIRVDYTKGYIDVNYKRMCRHQ 88 >4NBQ-A nrPDB Length = 715 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 41/68 (60%), Gaps = 3/68 (4%) Query: 23 NVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGY 82 V I + GA+V +L N +G++ +S++++ R+ ++ + G+ V VI +D++ G Sbjct: 650 TVVKITDFGAFVQILP--NTQGLVHISQIAQERVENVRDYLEEGQVIRVKVIEIDRQ-GR 706 Query: 83 IDLSKRRV 90 + LS +++ Sbjct: 707 VRLSMKQI 714 >2R5R-A nrPDB Length = 271 Score = 30.8 bits (68), Expect = 0.80, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 73 VIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY--------TKD 124 +IR+ +E+ +L P+E E + K V I+R VAEVL + + Sbjct: 190 IIRIAEEQASCELYGLLKRPDEKYVTERAYNNPKFVEDIVRDVAEVLNHDDRIDAYIVES 249 Query: 125 EQLESLFQRTAWVFDDKYKR 144 E ES+ +A+ ++ KR Sbjct: 250 ENFESIHNHSAYALIERDKR 269 >1PT7-A nrPDB Length = 437 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 7/68 (10%) Query: 117 EVLEYTKDEQLESLFQRTAWVFDD--KYKRPGYGAYDAFKHAVSDPSILDSLD---LNED 171 +VL++T + S Q AW D K +RPG G D +H + D +D+L LN + Sbjct: 30 KVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVG--DVTRHQLRDIPDIDALYFTMLNSN 87 Query: 172 EREVLINN 179 +R + +N Sbjct: 88 KRSIELNT 95 >1JCN-A nrPDB Length = 514 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 139 DDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVA 198 DDKY+ D A D +LDS N + +++ I ++ P I ++ A Sbjct: 255 DDKYR------LDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKY-PHLQVIGGNVVTA 307 Query: 199 CYGYEGIDAVKEALRAGLNCST 220 IDA + LR G+ C + Sbjct: 308 AQAKNLIDAGVDGLRVGMGCGS 329 >5EOV-A nrPDB Length = 220 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 5/69 (7%) Query: 165 SLDLNEDEREVLINNINRR-LTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENM 223 + L D R V++ N R LTP+A+ R D+ VA + + V AL + C++ + Sbjct: 71 AWSLRNDPRVVVLERTNARGLTPEAIGGRVDLVVADLSFISLATVLPAL---VGCASRDA 127 Query: 224 PIKINLIAP 232 I + L+ P Sbjct: 128 DI-VPLVKP 135 >3A9Z-A nrPDB Length = 432 Score = 28.5 bits (62), Expect = 3.5, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 10/81 (12%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMIL-LSELSRRRIRSINKLIRIGRNECVVV 73 EVED++ ++ V+++ NN G+I+ +SE+SRR I+++N+ IR V+ Sbjct: 164 EVEDILA----AVRPTTCLVTIMLANNETGVIMPISEISRR-IKALNQ-IRAASGLPRVL 217 Query: 74 IRVDKEKGYIDLSKRRVSPEE 94 + D + L KRRV E+ Sbjct: 218 VHTDAAQA---LGKRRVDVED 235 >1E3H-A nrPDB Length = 757 Score = 28.5 bits (62), Expect = 4.4, Method: Compositional matrix adjust. Identities = 18/76 (23%), Positives = 42/76 (55%), Gaps = 7/76 (9%) Query: 14 PEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSR----RRIRSINKLIRIGRNE 69 PEV + ++ +V GA+VSLL + G++ +S++ + +R+ ++ ++ +G+ Sbjct: 665 PEVGERILGSVVKTTTFGAFVSLLPGKD--GLLHISQIRKLAGGKRVENVEDVLGVGQKV 722 Query: 70 CVVVIRVDKEKGYIDL 85 V + +D +G + L Sbjct: 723 QVEIAEIDS-RGKLSL 737 >1XDU-A nrPDB Length = 374 Score = 27.7 bits (60), Expect = 5.9, Method: Compositional matrix adjust. Identities = 21/90 (23%), Positives = 43/90 (47%), Gaps = 7/90 (7%) Query: 157 VSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGL 216 +S S + L+ + + +VL+ N+ +TP A+++ A + + + G D + AGL Sbjct: 1 MSSSSPGEPLEPTDQDLDVLLKNLGNLVTPMALRVAATLRLVDHLLAGADTL-----AGL 55 Query: 217 NCSTENMPIKINLIAPPRYVMTTTTLERTE 246 T+ P ++ + R++ LE E Sbjct: 56 ADRTDTHPQALSRLV--RHLTVVGVLEGGE 83 >1YZ7-A nrPDB Length = 188 Score = 27.3 bits (59), Expect = 7.8, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 6/117 (5%) Query: 150 YDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVK 209 Y AF+ A D + + ++ VL I+ + V I A+ E+ G++ +K Sbjct: 50 YAAFEDAAKDGIDVLKGHVPDEWLPVLKEIIDNYVEVPTVTIDAEFEITVPKPNGVEIIK 109 Query: 210 EAL-RAGLNCSTE-NMPIKINLIAPPRYVMTTTTLERTEGLSVL----SQAMAVIKE 260 EAL RA + E ++ +K + PRY + T + + VL + + VIKE Sbjct: 110 EALIRARDRANKEKDVEVKFTYLGAPRYRIDITAPDYYKAEEVLESIAEEILRVIKE 166 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6O9Z-L nrPDB 461 e-130 6FEC-P nrPDB 395 e-110 3JAQ-j nrPDB 389 e-109 1YZ6-A nrPDB 273 6e-74 3CW2-C nrPDB 272 1e-73 1KL9-A nrPDB 269 1e-72 2A1A-A nrPDB 236 1e-62 2K4K-A nrPDB 94 6e-20 Sequences not found previously or not previously below threshold: 1YZ7-A nrPDB 156 1e-38 2QMU-B nrPDB 75 5e-14 3CDI-A nrPDB 71 7e-13 4NBQ-A nrPDB 67 8e-12 5X8P-8 nrPDB 67 1e-11 5YJJ-A nrPDB 62 3e-10 6D6K-A nrPDB 61 7e-10 6H58-y nrPDB 57 8e-09 5C9S-B nrPDB 57 1e-08 4AIM-A nrPDB 56 3e-08 1E3H-A nrPDB 55 4e-08 1LUZ-A nrPDB 49 2e-06 3BZK-A nrPDB 49 3e-06 2BA0-A nrPDB 43 1e-04 5XWM-A nrPDB 35 0.037 1GO3-E nrPDB 34 0.081 3SMA-A nrPDB 33 0.16 2B3Y-A nrPDB 32 0.26 2E8B-A nrPDB 32 0.39 2LLE-A nrPDB 31 1.0 5U4H-A nrPDB 31 1.1 3LN6-A nrPDB 30 1.4 5MMM-c nrPDB 30 1.8 2R17-C nrPDB 30 1.8 1GG3-A nrPDB 29 2.5 4QIW-E nrPDB 29 2.9 2R5R-A nrPDB 29 3.8 3GYW-A nrPDB 28 6.6 3FS3-A nrPDB 27 8.9 3B8P-A nrPDB 27 9.8 >6O9Z-L nrPDB Length = 323 Score = 461 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 314/314 (100%), Positives = 314/314 (100%) Query: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK Sbjct: 10 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 69 Query: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY Sbjct: 70 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 129 Query: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 181 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN Sbjct: 130 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 189 Query: 182 RRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTT 241 RRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTT Sbjct: 190 RRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTT 249 Query: 242 LERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVD 301 LERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVD Sbjct: 250 LERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVD 309 Query: 302 GDDDAEEMEAKAED 315 GDDDAEEMEAKAED Sbjct: 310 GDDDAEEMEAKAED 323 >6FEC-P nrPDB Length = 266 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 264/266 (99%), Positives = 265/266 (99%) Query: 6 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRI 65 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRI Sbjct: 1 CRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRI 60 Query: 66 GRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE 125 GRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE Sbjct: 61 GRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDE 120 Query: 126 QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLT 185 QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLT Sbjct: 121 QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLT 180 Query: 186 PQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERT 245 PQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTE MPIKINLIAPPRYVMTTTTLERT Sbjct: 181 PQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERT 240 Query: 246 EGLSVLSQAMAVIKEKIEEKRGVFNV 271 EGLSVL+QAMAVIKEKIEEKRGVFNV Sbjct: 241 EGLSVLNQAMAVIKEKIEEKRGVFNV 266 >3JAQ-j nrPDB Length = 304 Score = 389 bits (1000), Expect = e-109, Method: Composition-based stats. Identities = 160/298 (53%), Positives = 216/298 (72%), Gaps = 9/298 (3%) Query: 1 MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN 60 M CRFY++K+PE++D+VMVNV+ IAEMGAYV LLEY+NIEGMILLSELSRRRIRSI Sbjct: 1 MSTSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ 60 Query: 61 KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE 120 KLIR+G+N+ VV+RVDKEKGYIDLSKRRVS E+ IKCE+K+ KSKTV+SILR+ AE + Sbjct: 61 KLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQ 120 Query: 121 YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLN-EDEREVLINN 179 LE L++ AW K+ AY+AFK ++ D ++ + ++ +D + L N Sbjct: 121 IP----LEELYKTIAWPLSRKFGH----AYEAFKLSIIDETVWEGIEPPSKDVLDELKNY 172 Query: 180 INRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTT 239 I++RLTPQAVKIRAD+EV+C+ YEGIDA+K+AL++ + STE M +K+ L+A P YV+TT Sbjct: 173 ISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVKLVAAPLYVLTT 232 Query: 240 TTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQMERLEREN 297 L++ +G+ L A+ I E I + GV N+ M PK VT T++ EL +E E +N Sbjct: 233 QALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQALLESKELDN 290 >1YZ6-A nrPDB Length = 274 Score = 273 bits (699), Expect = 6e-74, Method: Composition-based stats. Identities = 67/258 (25%), Positives = 123/258 (47%), Gaps = 10/258 (3%) Query: 12 KFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECV 71 ++PE + V+ V+ I GA++ L EY E + +SE++ +R+I ++ G+ Sbjct: 6 EYPEEGEFVVATVKRIHNYGAFLELDEYPGKEAFMHISEVASTWVRNIRDYLKEGQKVVA 65 Query: 72 VVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLF 131 VIRVD KG+IDLS RRV+ ++ +F +++ ++L+ AE L + E+ + Sbjct: 66 KVIRVDPRKGHIDLSLRRVTQQQRKAKLQEFKRAQKAENLLKLAAEKL----GKDFETAW 121 Query: 132 QRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKI 191 + ++++ Y AF+ A D + + ++ VL I+ + V I Sbjct: 122 REVWVPLEEEWGE----VYAAFEDAAKDGIDVLKGHVPDEWLPVLKEIIDNYVEVPTVTI 177 Query: 192 RADIEVACYGYEGIDAVKEAL-RAGLNCSTE-NMPIKINLIAPPRYVMTTTTLERTEGLS 249 A+ E+ G++ +KEAL RA + E ++ +K + PRY + T + + Sbjct: 178 DAEFEITVPKPNGVEIIKEALIRARDRANKEKDVEVKFTYLGAPRYRIDITAPDYYKAEE 237 Query: 250 VLSQAMAVIKEKIEEKRG 267 VL I I+E G Sbjct: 238 VLESIAEEILRVIKEAGG 255 >3CW2-C nrPDB Length = 266 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 67/261 (25%), Positives = 130/261 (49%), Gaps = 15/261 (5%) Query: 8 FYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGR 67 + + K P ++++ V+ + + G+YVSL EY ++ + SE+S + +++I +++ R Sbjct: 3 YSRSKLPSEGEILIATVKQVFDYGSYVSLDEYGGLQAFLPWSEVSSKWVKNIRDVLKENR 62 Query: 68 NECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQL 127 V VIRVD+ KG +D+S ++V+ +E K ++ K + + IL V++ L+ ++ + Sbjct: 63 KVIVKVIRVDRRKGTVDVSLKKVTDDERRKKNLQWKKIQRLDKILELVSQKLKLSEKDA- 121 Query: 128 ESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQ 187 +++ AW + KY P A K IL + E + L+ ++ + Sbjct: 122 ---WEQVAWKLEAKYGDPITAIEKAVKEG---EKILIDAGVPEIWVKPLLEEASKHAEER 175 Query: 188 AVKIRADIEVACYGYEGIDAVKEALRAGLNCSTEN----MPIKINLIAPPRY---VMTTT 240 VK+ I V G++ +KE + L ++ + IKI I PRY V+ T Sbjct: 176 KVKMSGLITVRTNEPLGVEKIKEVISKALENIEQDYESLLNIKIYTIGAPRYRVDVVGTN 235 Query: 241 TLERTEGLS-VLSQAMAVIKE 260 E +E L+ ++S + + KE Sbjct: 236 PKEASEALNQIISNLIKIGKE 256 >1KL9-A nrPDB Length = 182 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 182/182 (100%), Positives = 182/182 (100%) Query: 2 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 61 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK Sbjct: 1 PGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINK 60 Query: 62 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 121 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY Sbjct: 61 LIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEY 120 Query: 122 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 181 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN Sbjct: 121 TKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNIN 180 Query: 182 RR 183 RR Sbjct: 181 RR 182 >2A1A-A nrPDB Length = 175 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 103/182 (56%), Positives = 136/182 (74%), Gaps = 9/182 (4%) Query: 3 GLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKL 62 CRFY++K+PE++D+VMVNV+ IAEMGAYV LLEY+NIEGMILLSELSRRRIRSI KL Sbjct: 2 SSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKL 61 Query: 63 IRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYT 122 IR+G+N+ VV+RVDKEKGYIDLSKRRVS E+ IKCE+K+ KSKTV+SILR+ AE + Sbjct: 62 IRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIP 121 Query: 123 KDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLN-EDEREVLINNIN 181 LE L++ AW K+ AY+AFK ++ D ++ + ++ +D + L N I+ Sbjct: 122 ----LEELYKTIAWPLSRKFGH----AYEAFKLSIIDETVWEGIEPPSKDVLDELKNYIS 173 Query: 182 RR 183 +R Sbjct: 174 KR 175 >1YZ7-A nrPDB Length = 188 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 37/176 (21%), Positives = 74/176 (42%), Gaps = 10/176 (5%) Query: 94 EAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAF 153 + +F +++ ++L+ AE L + E+ ++ ++++ Y AF Sbjct: 2 QRKAKLQEFKRAQKAENLLKLAAEKL----GKDFETAWREVWVPLEEEWGE----VYAAF 53 Query: 154 KHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEAL- 212 + A D + + ++ VL I+ + V I A+ E+ G++ +KEAL Sbjct: 54 EDAAKDGIDVLKGHVPDEWLPVLKEIIDNYVEVPTVTIDAEFEITVPKPNGVEIIKEALI 113 Query: 213 RAGLNCSTE-NMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRG 267 RA + E ++ +K + PRY + T + + VL I I+E G Sbjct: 114 RARDRANKEKDVEVKFTYLGAPRYRIDITAPDYYKAEEVLESIAEEILRVIKEAGG 169 >2K4K-A nrPDB Length = 130 Score = 94.5 bits (233), Expect = 6e-20, Method: Composition-based stats. Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 4/98 (4%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 EV V V + GA+V+L E +G++ +SE++ ++ IN+ + +G V V+ Sbjct: 6 EVGSVYTGKVTGLQAYGAFVALDE--ETQGLVHISEVTHGFVKDINEHLSVGDEVQVKVL 63 Query: 75 RVDKEKGYIDLSKR--RVSPEEAIKCEDKFTKSKTVYS 110 VD+EKG I LS R + +PE+ K ++ Sbjct: 64 AVDEEKGKISLSIRATQAAPEKKESKPRKPKAAQVSEE 101 >2QMU-B nrPDB Length = 93 Score = 74.8 bits (182), Expect = 5e-14, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 187 QAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTEN----MPIKINLIAPPRY---VMTT 239 + VK+ I V G++ +KE + L ++ + IKI I PRY V+ T Sbjct: 2 RKVKMSGLITVRTNEPLGVEKIKEVISKALENIEQDYESLLNIKIYTIGAPRYRVDVVGT 61 Query: 240 TTLERTEGLS-VLSQAMAVIKE 260 E +E L+ ++S + + KE Sbjct: 62 NPKEASEALNQIISNLIKIGKE 83 >3CDI-A nrPDB Length = 723 Score = 71.0 bits (172), Expect = 7e-13, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 43/79 (54%), Gaps = 3/79 (3%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 EV V V I + GA+V++ EG++ +S+++ +R+ + +++G+ V V+ Sbjct: 626 EVGRVYTGKVTRIVDFGAFVAI--GGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVL 683 Query: 75 RVDKEKGYIDLSKRRVSPE 93 VD +G I LS + + + Sbjct: 684 EVD-RQGRIRLSIKEATEQ 701 >4NBQ-A nrPDB Length = 715 Score = 67.1 bits (162), Expect = 8e-12, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 43/76 (56%), Gaps = 3/76 (3%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 E+ V V I + GA+V +L N +G++ +S++++ R+ ++ + G+ V VI Sbjct: 642 ELGKVYEGTVVKITDFGAFVQIL--PNTQGLVHISQIAQERVENVRDYLEEGQVIRVKVI 699 Query: 75 RVDKEKGYIDLSKRRV 90 +D +G + LS +++ Sbjct: 700 EID-RQGRVRLSMKQI 714 >5X8P-8 nrPDB Length = 370 Score = 66.7 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 52/101 (51%), Gaps = 6/101 (5%) Query: 16 VEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIR 75 + VV V+S+ GA++ + I G++ +S++S R+ I +++ G V+++ Sbjct: 219 IGSVVTGTVQSLKPYGAFIDI---GGINGLLHVSQISHDRVSDIATVLQPGDTLKVMILS 275 Query: 76 VDKEKGYIDLSKRRVSP---EEAIKCEDKFTKSKTVYSILR 113 D+E+G + LS +++ P + + F K++ + R Sbjct: 276 HDRERGRVSLSTKKLEPTPGDMIRNPKLVFEKAEEMAQTFR 316 >5YJJ-A nrPDB Length = 713 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 43/80 (53%), Gaps = 3/80 (3%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 EV V V+ I + GA+V L + + ++ +S++S+ RI + +++IG V + Sbjct: 636 EVGQVYHAKVKRIEKYGAFVEL--FPGKDALLHISQISQERINKVEDVLKIGDTIEVKIT 693 Query: 75 RVDKEKGYIDLSKRRVSPEE 94 +DK+ G ++ S + + + Sbjct: 694 EIDKQ-GRVNASHKVLEQSK 712 >6D6K-A nrPDB Length = 705 Score = 61.0 bits (146), Expect = 7e-10, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 40/78 (51%), Gaps = 3/78 (3%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 E + V I E GA+V+++ +G++ +S++S RI ++ +++ G+ V V Sbjct: 630 EPGKIYDGKVIRIVEFGAFVNIM--PGTDGLLHISQISNERIANVTDVLKEGQEVKVQVQ 687 Query: 75 RVDKEKGYIDLSKRRVSP 92 VD G I L+ + + Sbjct: 688 DVDNR-GRIKLTMKDIEQ 704 >6H58-y nrPDB Length = 557 Score = 57.5 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 51/94 (54%), Gaps = 3/94 (3%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 + V V+++ + GA+V L ++G++ +++++ +R++ ++++ +G V V+ Sbjct: 190 QEGMEVKGIVKNLTDYGAFVDL---GGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVL 246 Query: 75 RVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTV 108 + D+E+ + L +++ + + ++ + + Sbjct: 247 KFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKL 280 >5C9S-B nrPDB Length = 572 Score = 57.1 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 38/72 (52%) Query: 17 EDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRV 76 DV ++S+ + G +V L N+ G+ ++E++ ++ ++ L +G +V++ Sbjct: 108 GDVFEGTIKSVTDFGVFVKLDNTVNVTGLAHITEIADKKPEDLSALFGVGDRVKAIVLKT 167 Query: 77 DKEKGYIDLSKR 88 + EK I LS + Sbjct: 168 NPEKKQISLSLK 179 >4AIM-A nrPDB Length = 726 Score = 55.6 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 39/79 (49%), Gaps = 3/79 (3%) Query: 15 EVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVI 74 E+ + V + + GA+V+ + +G++ +S++S R+ + +++ G+ V ++ Sbjct: 636 EIGKIYDGKVVKVVDFGAFVNF--FGAKDGLVHVSQISNERVAKPSDVLKEGQMVKVKLL 693 Query: 75 RVDKEKGYIDLSKRRVSPE 93 D G LS + V E Sbjct: 694 GFDDR-GKTKLSMKVVDQE 711 >1E3H-A nrPDB Length = 757 Score = 55.2 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 41/76 (53%), Gaps = 7/76 (9%) Query: 14 PEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSR----RRIRSINKLIRIGRNE 69 PEV + ++ +V GA+VSLL +G++ +S++ + +R+ ++ ++ +G+ Sbjct: 665 PEVGERILGSVVKTTTFGAFVSLL--PGKDGLLHISQIRKLAGGKRVENVEDVLGVGQKV 722 Query: 70 CVVVIRVDKEKGYIDL 85 V + +D G + L Sbjct: 723 QVEIAEIDSR-GKLSL 737 >1LUZ-A nrPDB Length = 88 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Query: 13 FPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLS-ELSRRRIRSINKLIRIGRNECV 71 P DV+ V + Y+ L +Y + E ++ S ++ R + +G+ V Sbjct: 8 LPNAGDVIKGRVYE-KDYALYIYLFDYPHFEAILAESVKMHMDRYVEYRDKL-VGKTVKV 65 Query: 72 VVIRVDKEKGYIDLSKRRVSPEE 94 VIRVD KGYID++ +R+ + Sbjct: 66 KVIRVDYTKGYIDVNYKRMCRHQ 88 >3BZK-A nrPDB Length = 785 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 17 EDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRV 76 V+ V ++ GA+V + + +G++ +S LS + ++ ++++ G V V+ V Sbjct: 655 GMVLEGVVTNVTNFGAFVDIGVHQ--DGLVHISALSEKFVKDPYEVVKAGDIVKVKVMEV 712 Query: 77 DKEKGYIDLSKR 88 D + + LS R Sbjct: 713 DIPRNRVGLSMR 724 >2BA0-A nrPDB Length = 229 Score = 43.2 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 4/76 (5%) Query: 14 PEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSR-RRIRSINKLIRIGRNECVV 72 P V DVV+ +R +A G ++ Y+ + + +SE + + N+++ IG Sbjct: 55 PSVGDVVIGIIREVAANGW--AVDIYSPYQAFLPVSENPEMKPNKKPNEVLDIGDAIIAK 112 Query: 73 VIRVDKEKGYIDLSKR 88 V+ +D K + L+ + Sbjct: 113 VLNIDP-KMKVTLTMK 127 >5XWM-A nrPDB Length = 383 Score = 35.2 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 51/284 (17%), Positives = 91/284 (32%), Gaps = 68/284 (23%) Query: 6 CRFYQ--------------HKFPEVEDVVMVNVR--SIAEMGAYVSLLEYNNIE----GM 45 CRF Q +FP VV V +++ + +Y ++ GM Sbjct: 35 CRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGM 94 Query: 46 ILLSEL-SRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTK 104 ++ E +R ++++ IR +++ + IR E +D SKR + K D + Sbjct: 95 MMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRV 154 Query: 105 SKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILD 164 + V +IL D S F + + Y H+ D + Sbjct: 155 FERVANILH---------DDCAFLSAFGDVSKP-ERYSGDNI--IYKPPGHSAPD-MVYL 201 Query: 165 SLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTENMP 224 N +V N I + P +I G + E +P Sbjct: 202 GAMTN---FDVTYNWIQDKCVPLVREI-------------------TFENGEELTEEGLP 239 Query: 225 IKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGV 268 +++ E TE L + V ++ I EK + Sbjct: 240 ----------FLILFHMKEDTESLEIFQN--EVARQLISEKGTI 271 >1GO3-E nrPDB Length = 187 Score = 34.0 bits (76), Expect = 0.081, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 45/112 (40%), Gaps = 27/112 (24%) Query: 14 PEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRI-----------RSINKL 62 PE+ +++ V + E G++V L ++G+I +S++ + + K+ Sbjct: 79 PEMYELIEGEVVDVVEFGSFVRL---GPLDGLIHVSQIMDDYVSYDPKREAIIGKETGKV 135 Query: 63 IRIGRNECVVVIRVD-----KEKGYIDLSKRR--------VSPEEAIKCEDK 101 + IG ++ + K I L+ R+ + E+A K + Sbjct: 136 LEIGDYVRARIVAISLKAERKRGSKIALTMRQPYLGKLEWIEEEKAKKQNQE 187 >3SMA-A nrPDB Length = 286 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 16/49 (32%) Query: 132 QRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI 180 Q D + G F +SDPS + ED V+ + Sbjct: 59 QAVVLALQDAVGKEGTLVMPTFSGDLSDPSTWRRPPVPEDWWPVIREQM 107 >2B3Y-A nrPDB Length = 888 Score = 32.5 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 23/125 (18%), Positives = 44/125 (35%), Gaps = 10/125 (8%) Query: 77 DKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAW 136 D G + S R + C++ K + + +IL T+ + +E F+ Sbjct: 28 DSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENILHW-----NVTQHKNIEVPFKPARV 82 Query: 137 VFDDKYKRPGYGAYDAFKHAVS----DPSILDSLDLNEDEREVLIN-NINRRLTPQAVKI 191 + D P + A + AV DP ++ + + + I + NRR Sbjct: 83 ILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFNRRADSLQKNQ 142 Query: 192 RADIE 196 + E Sbjct: 143 DLEFE 147 >2E8B-A nrPDB Length = 201 Score = 31.7 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 52/132 (39%), Gaps = 3/132 (2%) Query: 88 RRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDD-KYKRPG 146 +R ++ + + VY + V + + ++ + F V D+ + Sbjct: 26 KRFGEDKLLYEIKGKKVIERVYETAKSVFKEVYIVAKDREKFSFLNAPVVLDEFEESASI 85 Query: 147 YGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIE--VACYGYEG 204 G Y A KHA + + S DL ++E ++ + P +V + V Y + Sbjct: 86 IGLYTALKHAKEENVFVLSGDLPLMKKETVLYVLENFKEPVSVAKTEKLHTLVGVYSKKL 145 Query: 205 IDAVKEALRAGL 216 ++ ++E ++ G Sbjct: 146 LEKIEERIKKGD 157 >2LLE-A nrPDB Length = 234 Score = 30.5 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 31/80 (38%), Gaps = 12/80 (15%) Query: 182 RRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLN--------CSTENMPIKINLIAPP 233 + L P V + + GIDA+KE ++ N + M I+ Sbjct: 22 KELKPDIVTMD----ITMPEMNGIDAIKEIMKIDPNAKIIVCSAMGQQAMVIEAIKAGAK 77 Query: 234 RYVMTTTTLERTEGLSVLSQ 253 +++ T +E ++ L+Q Sbjct: 78 GFIVNTAAVENPSLITQLAQ 97 >5U4H-A nrPDB Length = 421 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 43/110 (39%), Gaps = 5/110 (4%) Query: 203 EGIDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKI 262 +G+ ++ A R M IK + + T TL T S+ AV+ ++I Sbjct: 181 DGVTTIRNAAREPEITDLAQMLIK---MGAKIEGLDTDTLVVTGVESLHGCEYAVVADRI 237 Query: 263 E--EKRGVFNVQMEPKVVTDTDETELARQMERLERENAEVDGDDDAEEME 310 E + T TD + L +++ E AEV DD E++ Sbjct: 238 ETGSYLAAAAITGGRVKTTHTDPSLLEAVLDKFEEMGAEVTRGDDWIELD 287 >3LN6-A nrPDB Length = 750 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 225 IKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDET 284 I+ + P ++T + E + L V I ++ + M PKV ++ Sbjct: 55 IQTDYSEPQLELITPIAKDSQEAIRFLKAISDVAGRSINHDEYLWPLSMPPKV--REEDI 112 Query: 285 ELARQMERLERE 296 ++A+ + E + Sbjct: 113 QIAQLEDAFEYD 124 >5MMM-c nrPDB Length = 218 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 200 YGYEGIDAVKEALRAGLNCSTENMPIKINLIAPP 233 +G++ +K ++ LNC + I I IA P Sbjct: 87 NRPQGVEDLKINVQKELNCVNRKLNIAITRIAKP 120 >2R17-C nrPDB Length = 298 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 28/58 (48%) Query: 205 IDAVKEALRAGLNCSTENMPIKINLIAPPRYVMTTTTLERTEGLSVLSQAMAVIKEKI 262 ++ +K+AL+ C ++ +++ + RY+ + VL+Q + I+E + Sbjct: 215 MECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDL 272 >1GG3-A nrPDB Length = 279 Score = 29.0 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 16/108 (14%), Positives = 43/108 (39%), Gaps = 7/108 (6%) Query: 9 YQHKFPEVEDV-VMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGR 67 Y+ P D+ + N + ++ G V L + ++EG+ ++ + + +RI R Sbjct: 165 YRSMTPAQADLEFLENAKKLSMYG--VDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINR 222 Query: 68 NECVVVIRVDKEKGYIDLSKRRVSPEEAIK----CEDKFTKSKTVYSI 111 V+++ ++ + R E+ + +K ++ + Sbjct: 223 FPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKV 270 >4QIW-E nrPDB Length = 190 Score = 29.0 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 33/76 (43%), Gaps = 19/76 (25%) Query: 30 MGAYVSLLEYNNIEGMILLSELSRRRI-----------RSINKLIRIGRNECVVVIRVDK 78 GA++ + ++G++ +S+L + + N+++++G +I V Sbjct: 95 YGAFIRI---GPMDGLVHISQLMDDYVVFDEKNRQFIGKETNRVLKLGDYVRARIIGVSV 151 Query: 79 -----EKGYIDLSKRR 89 + I+++ R+ Sbjct: 152 KSRVIRENKINMTMRQ 167 >2R5R-A nrPDB Length = 271 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 8/80 (10%) Query: 73 VIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE--------YTKD 124 +IR+ +E+ +L P+E E + K V I+R VAEVL + Sbjct: 190 IIRIAEEQASCELYGLLKRPDEKYVTERAYNNPKFVEDIVRDVAEVLNHDDRIDAYIVES 249 Query: 125 EQLESLFQRTAWVFDDKYKR 144 E ES+ +A+ ++ KR Sbjct: 250 ENFESIHNHSAYALIERDKR 269 >3GYW-A nrPDB Length = 249 Score = 27.8 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Query: 117 EVLEYTKDE--QLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVS--DPSILDSLDLNEDE 172 + L+ + E ES F+ ++ KY YD + A+ + + + +L E Sbjct: 12 KKLKLYQKEYYDYESKFEYELFLLRQKYHDLYGPIYDKRREALVGNGEAKIGTPNLPEFW 71 Query: 173 REVLINN 179 L NN Sbjct: 72 LRALRNN 78 >3FS3-A nrPDB Length = 359 Score = 27.5 bits (59), Expect = 8.9, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 24/64 (37%), Gaps = 2/64 (3%) Query: 118 VLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVS--DPSILDSLDLNEDEREV 175 L + ES F+ ++ KY YD + A+ + + + +L E Sbjct: 59 KLYQKEYYDYESKFEYELFLLRQKYHDLYGPIYDKRREALVGNGEAKIGTPNLPEFWLRA 118 Query: 176 LINN 179 L NN Sbjct: 119 LRNN 122 >3B8P-A nrPDB Length = 243 Score = 27.1 bits (58), Expect = 9.8, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 47 LLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSP----EEAIKCEDKF 102 +S + R + + I+ E + VD K I L + + +E + E K Sbjct: 85 YVSTTAEGAQRRLAEYIQQVDEEVAKELEVDL-KDNITLQTKTLQESLETQEVVAQEQKD 143 Query: 103 TKSKTVYSILRHVAE 117 + K + LR+ E Sbjct: 144 LRIKQIEEALRYADE 158 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.301 0.124 0.291 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,420,685 Number of Sequences: 36641 Number of extensions: 313757 Number of successful extensions: 1284 Number of sequences better than 10.0: 40 Number of HSP's better than 10.0 without gapping: 35 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 1220 Number of HSP's gapped (non-prelim): 74 length of query: 315 length of database: 10,336,785 effective HSP length: 97 effective length of query: 218 effective length of database: 6,782,608 effective search space: 1478608544 effective search space used: 1478608544 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (20.8 bits) S2: 59 (27.4 bits)