BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05156 (583 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2XRC-A nrPDB 1176 0.0 5O32-I nrPDB 517 e-147 3W94-A nrPDB 145 6e-35 3T2N-A nrPDB 144 2e-34 5TJX-A nrPDB 143 2e-34 2F83-A nrPDB 142 3e-34 6I44-A nrPDB 141 9e-34 1A5I-A nrPDB 140 1e-33 1P57-B nrPDB 138 7e-33 5GVT-A nrPDB 138 7e-33 1BDA-A nrPDB 137 1e-32 2OQ5-A nrPDB 136 3e-32 1FIW-A nrPDB 134 1e-31 6AOD-C nrPDB 131 7e-31 3F6U-H nrPDB 131 9e-31 1YC0-A nrPDB 131 9e-31 1FIZ-A nrPDB 130 2e-30 3P8G-A nrPDB 127 1e-29 2R0L-A nrPDB 125 7e-29 5UGG-A nrPDB 122 4e-28 3E0N-B nrPDB 122 4e-28 4DUR-A nrPDB 122 5e-28 3DFJ-A nrPDB 121 9e-28 3LC3-A nrPDB 121 1e-27 1BRU-P nrPDB 120 1e-27 4KKD-A nrPDB 120 1e-27 4DGJ-A nrPDB 120 2e-27 5LHN-A nrPDB 120 2e-27 4IGD-A nrPDB 119 3e-27 3BSQ-A nrPDB 119 3e-27 5ZFH-A nrPDB 119 3e-27 4H4F-A nrPDB 119 3e-27 1EKB-B nrPDB 117 2e-26 1SGF-G nrPDB 117 2e-26 4IW4-E nrPDB 116 2e-26 4XDE-A nrPDB 116 3e-26 4DJZ-B nrPDB 116 3e-26 1Q3X-A nrPDB 115 4e-26 1NPM-A nrPDB 115 5e-26 4MPW-A nrPDB 115 5e-26 1X7A-C nrPDB 115 7e-26 1LTO-A nrPDB 114 8e-26 2F91-A nrPDB 114 1e-25 5MS3-A nrPDB 114 1e-25 1ZJK-A nrPDB 114 2e-25 4AN7-A nrPDB 112 3e-25 1SC8-U nrPDB 112 4e-25 6BQM-A nrPDB 112 4e-25 1FXY-A nrPDB 112 5e-25 4FXG-H nrPDB 110 1e-24 4NFE-A nrPDB 110 2e-24 2CGA-A nrPDB 109 3e-24 1KIG-H nrPDB 109 3e-24 5FXL-A nrPDB 109 4e-24 1C5M-D nrPDB 109 4e-24 1ELV-A nrPDB 108 8e-24 1PYT-D nrPDB 107 1e-23 4J1Y-A nrPDB 105 4e-23 1F7Z-A nrPDB 105 5e-23 6QHB-A nrPDB 105 8e-23 1A0J-A nrPDB 104 9e-23 4Z6A-H nrPDB 103 2e-22 1SGF-A nrPDB 103 3e-22 3QUM-P nrPDB 102 4e-22 5UBM-A nrPDB 102 4e-22 2BDH-A nrPDB 101 1e-21 2TLD-E nrPDB 101 1e-21 1UTJ-A nrPDB 100 2e-21 2B9L-A nrPDB 100 3e-21 5C67-A nrPDB 98 1e-20 5KWM-A nrPDB 98 1e-20 4BXW-A nrPDB 98 1e-20 4WWY-A nrPDB 97 2e-20 1TON-A nrPDB 97 2e-20 1PQ7-A nrPDB 97 3e-20 1GPZ-A nrPDB 96 4e-20 1MD7-A nrPDB 96 4e-20 1AO5-A nrPDB 96 5e-20 2OLG-A nrPDB 96 6e-20 1SPJ-A nrPDB 95 6e-20 1FDP-A nrPDB 95 9e-20 1MZD-A nrPDB 95 1e-19 3TK9-A nrPDB 93 3e-19 1M9U-A nrPDB 93 4e-19 1FI8-A nrPDB 92 9e-19 2QY0-B nrPDB 91 1e-18 2PSX-A nrPDB 91 1e-18 1ELT-A nrPDB 91 2e-18 3I77-A nrPDB 90 2e-18 1YM0-A nrPDB 90 3e-18 5LPF-A nrPDB 89 6e-18 2FMJ-A nrPDB 89 8e-18 1KYN-A nrPDB 88 1e-17 2XXL-A nrPDB 88 1e-17 1MKW-K nrPDB 87 1e-17 2HLC-A nrPDB 86 6e-17 1EUF-A nrPDB 85 7e-17 2EEK-A nrPDB 85 9e-17 4LK4-A nrPDB 85 1e-16 1ETT-H nrPDB 84 2e-16 5FCR-A nrPDB 83 4e-16 1IAU-A nrPDB 83 4e-16 2ZKS-A nrPDB 83 4e-16 2V35-A nrPDB 81 1e-15 3BEU-A nrPDB 81 1e-15 2ASU-B nrPDB 81 1e-15 4NZQ-A nrPDB 80 3e-15 3NXP-A nrPDB 79 6e-15 4X0L-C nrPDB 79 6e-15 4WJG-C nrPDB 79 7e-15 3RP2-A nrPDB 78 1e-14 3G01-A nrPDB 77 1e-14 3K65-B nrPDB 77 2e-14 2AIQ-A nrPDB 77 2e-14 4F4O-C nrPDB 77 2e-14 1AZZ-A nrPDB 76 4e-14 1OP0-A nrPDB 76 4e-14 1GVZ-A nrPDB 75 6e-14 4GSO-A nrPDB 75 7e-14 1NN6-A nrPDB 75 7e-14 1ORF-A nrPDB 75 9e-14 4E7N-A nrPDB 73 3e-13 1SI5-H nrPDB 73 3e-13 1BQY-A nrPDB 73 3e-13 3H7O-A nrPDB 73 3e-13 3S9B-A nrPDB 73 4e-13 1FUJ-A nrPDB 72 5e-13 1FON-A nrPDB 72 8e-13 2OCV-B nrPDB 71 1e-12 5TO3-B nrPDB 71 1e-12 1EQ9-A nrPDB 71 1e-12 4Q7Y-A nrPDB 70 3e-12 1VR1-H nrPDB 69 6e-12 2PKA-B nrPDB 68 1e-11 3S69-A nrPDB 66 4e-11 5XRF-A nrPDB 64 1e-10 1AKS-B nrPDB 64 1e-10 2RDL-A nrPDB 62 1e-09 1AE5-A nrPDB 60 3e-09 3RU4-E nrPDB 60 3e-09 5XW8-A nrPDB 60 4e-09 2JET-C nrPDB 58 1e-08 1PPF-E nrPDB 58 1e-08 3VGC-B nrPDB 57 2e-08 2JET-B nrPDB 55 6e-08 3F1S-B nrPDB 55 9e-08 3H5C-B nrPDB 55 1e-07 3H7T-A nrPDB 54 2e-07 3M0C-C nrPDB 54 2e-07 2KAI-A nrPDB 54 2e-07 1N7D-A nrPDB 54 3e-07 5B4X-B nrPDB 52 8e-07 1BBR-H nrPDB 50 2e-06 1BBR-E nrPDB 50 3e-06 1RIW-B nrPDB 49 7e-06 2I6S-A nrPDB 49 8e-06 2HNT-F nrPDB 48 1e-05 1DLE-A nrPDB 43 3e-04 2HNT-C nrPDB 43 4e-04 2OK5-A nrPDB 42 0.001 2WIN-I nrPDB 41 0.001 5ZE3-A nrPDB 41 0.002 1EPT-B nrPDB 38 0.010 4A5W-B nrPDB 35 0.11 5H7V-A nrPDB 35 0.12 3OJY-A nrPDB 34 0.15 6H03-G nrPDB 34 0.17 6CXO-A nrPDB 34 0.18 6H03-D nrPDB 34 0.18 2WCY-A nrPDB 32 0.60 3OJY-B nrPDB 32 0.61 >2XRC-A nrPDB Length = 565 Score = 1176 bits (3042), Expect = 0.0, Method: Compositional matrix adjust. Identities = 564/565 (99%), Positives = 564/565 (99%) Query: 19 KVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATN 78 KVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATN Sbjct: 1 KVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATN 60 Query: 79 RRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTM 138 RRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTM Sbjct: 61 RRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTM 120 Query: 139 FICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTF 198 FICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTF Sbjct: 121 FICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTF 180 Query: 199 TKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKA 258 TKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKA Sbjct: 181 TKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKA 240 Query: 259 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRI 318 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASV QEETEILTADMDAERRRI Sbjct: 241 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVAQEETEILTADMDAERRRI 300 Query: 319 KSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTA 378 KSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTA Sbjct: 301 KSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTA 360 Query: 379 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD 438 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD Sbjct: 361 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD 420 Query: 439 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKF 498 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKF Sbjct: 421 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKF 480 Query: 499 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV 558 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV Sbjct: 481 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV 540 Query: 559 YTKVANYFDWISYHVGRPFISQYNV 583 YTKVANYFDWISYHVGRPFISQYNV Sbjct: 541 YTKVANYFDWISYHVGRPFISQYNV 565 >5O32-I nrPDB Length = 244 Score = 517 bits (1331), Expect = e-147, Method: Compositional matrix adjust. Identities = 244/244 (100%), Positives = 244/244 (100%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 460 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSID 519 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSID Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSID 180 Query: 520 ACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFIS 579 ACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFIS Sbjct: 181 ACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFIS 240 Query: 580 QYNV 583 QYNV Sbjct: 241 QYNV 244 >3W94-A nrPDB Length = 235 Score = 145 bits (365), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 84/238 (35%), Positives = 128/238 (53%), Gaps = 14/238 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 +VGG A+ G PW V++ CG IG W+LTAAHC+ TH Q W+ V+ Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTH-LQYWSAVLG- 58 Query: 400 IHP----DLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 +H + + + I VDRII ++NYN T + DIA++ +++ N + L P C+ Sbjct: 59 LHAQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVL----PVCLA 114 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAG 512 F C ++GWGR+ + + LQ EV L+ C + + M CAG Sbjct: 115 SEDQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAG 174 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 +G +D+C+GDSGGPL+C++ T + GV S+G CG+PE PG Y +V+ + WI+ Sbjct: 175 YPEGGVDSCQGDSGGPLMCLEDARWTLI-GVTSFGVGCGRPERPGAYARVSAFTSWIA 231 >3T2N-A nrPDB Length = 372 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 92/258 (35%), Positives = 132/258 (51%), Gaps = 30/258 (11%) Query: 331 NRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASKTH 388 R + RIVGG+ LG PWQV+++ CGG + G W+LTAAHC R Sbjct: 109 GRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLS 168 Query: 389 RYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENY------NAGTYQNDIALIEMKKDGNKK 442 R++++ V P ++ ++ V ++H Y N+ NDIAL+ + Sbjct: 169 RWRVFAGAVAQASPHGLQLGVQAV---VYHGGYLPFRDPNSEENSNDIALVHLSS----- 220 Query: 443 DCELPRS---IPACVPWSPYLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLIS----N 494 LP + P C+P + C V+GWG + ++ LQ V +IS N Sbjct: 221 --PLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCN 278 Query: 495 CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVW---GVVSWGENCG 551 + FYGN+ K M CAG +G IDAC+GDSGGP VC D+ + T W G+VSWG C Sbjct: 279 GADFYGNQIKPK-MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCA 337 Query: 552 KPEFPGVYTKVANYFDWI 569 + PGVYTKV+++ +WI Sbjct: 338 LAQKPGVYTKVSDFREWI 355 >5TJX-A nrPDB Length = 263 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 90/238 (37%), Positives = 128/238 (53%), Gaps = 13/238 (5%) Query: 339 RIVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHR-YQIWT 394 RIVGG + G+ PWQV+++ A CGG IG W+LTAAHC ++I++ Sbjct: 15 RIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 74 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 454 +++ + K + II H+NY +DIALI+++ + + P S+P+ Sbjct: 75 GILE-LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSKG 133 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECA 511 S C V+GWG K+ + + LQ + L++N C K Y + + M CA Sbjct: 134 DTSTIY----TNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 189 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G +G DACKGDSGGPLVC N + + G+ SWGE C + E PGVYTKVA Y DWI Sbjct: 190 GYKEGGKDACKGDSGGPLVC-KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 246 >2F83-A nrPDB Length = 625 Score = 142 bits (359), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 110/329 (33%), Positives = 156/329 (47%), Gaps = 31/329 (9%) Query: 250 QSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTA 309 +S E C K C C+ P+Q CN E + C S T+IL Sbjct: 312 KSHEACQKLCTN-AVRCQFFTYTPAQASCN--------EGKGKCYLKLSSNGSPTKILHG 362 Query: 310 DMDAERRRIKSLLPKLSCGVKNRMHIRRK-RIVGGKRAQLGDLPWQVAIKDASGIT---C 365 R I +L C + N + K RIVGG + G+ PWQV + S C Sbjct: 363 -----RGGISGYTLRL-CKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLC 416 Query: 366 GGIYIGGCWILTAAHCLRASKTHR-YQIWTTVVDWIHPDLKRIVIEY-VDRIIFHENYNA 423 GG IG WILTAAHC ++ + ++++ +++ ++K + V II H+ Y Sbjct: 417 GGSIIGNQWILTAAHCFYGVESPKILRVYSGILN--QSEIKEDTSFFGVQEIIIHDQYKM 474 Query: 424 GTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV-F 482 DIAL++++ N D + P C+P C V+GWG K +++ Sbjct: 475 AESGYDIALLKLETTVNYTDSQRP----ICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQN 530 Query: 483 SLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYV 540 +LQ ++ L++N C K Y +M CAG +G DACKGDSGGPL C N V ++ Sbjct: 531 TLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKH-NEVWHL 589 Query: 541 WGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G+ SWGE C + E PGVYT V Y DWI Sbjct: 590 VGITSWGEGCAQRERPGVYTNVVEYVDWI 618 >6I44-A nrPDB Length = 627 Score = 141 bits (355), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 87/238 (36%), Positives = 125/238 (52%), Gaps = 13/238 (5%) Query: 339 RIVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHR-YQIWT 394 RIVGG ++ G+ PWQV+++ A CGG IG W+LTAAHC ++I++ Sbjct: 379 RIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 438 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 454 ++ + K + II H+NY +DIALI+++ + + P C+ Sbjct: 439 GILQ-LSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKP----ICL 493 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECA 511 P C V+GWG + + + LQ + L++N C K Y + + M CA Sbjct: 494 PSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCA 553 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G +G DACKGD+GGPLVC N + + G+ SWGE C + E PGVYTKVA Y DWI Sbjct: 554 GYKEGGKDACKGDAGGPLVC-KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 610 >1A5I-A nrPDB Length = 265 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 93/247 (37%), Positives = 132/247 (53%), Gaps = 20/247 (8%) Query: 341 VGGKRAQLGDLPWQVAI----KDASG--ITCGGIYIGGCWILTAAHCLRASK-THRYQIW 393 GG + PWQ AI + +SG CGGI I CW+LTAAHC + S + ++ Sbjct: 15 TGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVV 74 Query: 394 TTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPAC 453 + P + + V + I H+ ++ TY NDIAL+++K D + E C Sbjct: 75 LGRTYRVKPGEEEQTFK-VKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAIC 133 Query: 454 VPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLI--SNCS-KFYGNRFYEKEM 508 +P + C +SG+G+ K + +S L+ G V+L S C+ KF N+ M Sbjct: 134 LPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNM 193 Query: 509 ECAG-TYDGSI-----DACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKV 562 CAG T G I DAC+GDSGGPLVCM+ N++T + G++SWG CG+ + PGVYTKV Sbjct: 194 LCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLL-GIISWGVGCGEKDVPGVYTKV 252 Query: 563 ANYFDWI 569 NY WI Sbjct: 253 TNYLGWI 259 >1P57-B nrPDB Length = 255 Score = 138 bits (347), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 90/249 (36%), Positives = 129/249 (51%), Gaps = 30/249 (12%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASKTHRYQIWTTVV 397 IVGG+ LG PWQV+++ CGG + G W+LTAAHC R R++++ V Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENY------NAGTYQNDIALIEMKKDGNKKDCELPRS-- 449 P ++ ++ V ++H Y N+ NDIAL+ + LP + Sbjct: 61 AQASPHGLQLGVQAV---VYHGGYLPFRDPNSEENSNDIALVHLSS-------PLPLTEY 110 Query: 450 -IPACVPWSPYLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLIS----NCSKFYGNRF 503 P C+P + C V+GWG + ++ LQ V +IS N + FYGN+ Sbjct: 111 IQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQI 170 Query: 504 YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVW---GVVSWGENCGKPEFPGVYT 560 K M CAG +G IDAC+GDSGGP VC D+ + T W G+VSWG C + PGVYT Sbjct: 171 KPK-MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYT 229 Query: 561 KVANYFDWI 569 KV+++ +WI Sbjct: 230 KVSDFREWI 238 >5GVT-A nrPDB Length = 250 Score = 138 bits (347), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 88/237 (37%), Positives = 123/237 (51%), Gaps = 13/237 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKD---ASGITCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTT 395 IVGG A LG+ PWQV+++ + CGG IG W+LTAAHC ++I+ Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 ++ + K + +I H+ Y DIALI+++ N + + P S+P+ Sbjct: 61 ILS-LSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKAD 119 Query: 456 WSPYLFQPNDTCIVSGWGREKDN-ERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAG 512 + C V+GWG K+ E LQ + L+ N C K Y + K+M CAG Sbjct: 120 TNTIY----TNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAG 175 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 +G DACKGDSGGPLVC + V G+ SWGE C + + PGVYTKV+ Y DWI Sbjct: 176 YKEGGTDACKGDSGGPLVCKHSGRWQLV-GITSWGEGCARKDQPGVYTKVSEYMDWI 231 >1BDA-A nrPDB Length = 265 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 92/251 (36%), Positives = 131/251 (52%), Gaps = 24/251 (9%) Query: 339 RIVGGKRAQLGDLPWQVAI------KDASGITCGGIYIGGCWILTAAHCLRAS-KTHRYQ 391 RI GG A + PWQ AI CGGI I CWIL+AAHC + H Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNK--KDCELPRS 449 + + P + E V++ I H+ ++ TY NDIAL+++K D ++ ++ + R+ Sbjct: 73 VILGRTYRVVPGEEEQKFE-VEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRT 131 Query: 450 IPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLI--SNC-SKFYGNRFY 504 + C+P + C +SG+G+ + +S L+ V+L S C S+ NR Sbjct: 132 V--CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTV 189 Query: 505 EKEMECAG-TYDGSI-----DACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV 558 M CAG T G DAC+GDSGGPLVC++ +T V G++SWG CG+ + PGV Sbjct: 190 TDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLV-GIISWGLGCGQKDVPGV 248 Query: 559 YTKVANYFDWI 569 YTKV NY DWI Sbjct: 249 YTKVTNYLDWI 259 >2OQ5-A nrPDB Length = 232 Score = 136 bits (342), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 87/240 (36%), Positives = 121/240 (50%), Gaps = 14/240 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + G+ PWQ +++ CG I W+++AAHC K + V Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 +KR + RII HE Y ++ DI+L E+ + + R C+P + Y Sbjct: 61 KPSKMKR----GLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNA-VHR---VCLPDASY 112 Query: 460 LFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLIS----NCSKFYGNRFYEKEMECAGTY 514 FQP D V+G+G K D L+ +V LI N + Y N M CAG+ Sbjct: 113 EFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY-NDAITPRMLCAGSL 171 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 +G DAC+GDSGGPLV DA ++ Y+ G+VSWG+ C KP PGVYT+V DWI+ G Sbjct: 172 EGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 231 >1FIW-A nrPDB Length = 290 Score = 134 bits (337), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 92/258 (35%), Positives = 131/258 (50%), Gaps = 32/258 (12%) Query: 340 IVGGKRAQLGDLPWQVAIK------DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIW 393 I+GG+ A G PW V+++ + CGG + W+LTAAHC R K + W Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKK--KVTDW 58 Query: 394 TTV-----VDW-----IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKD 443 + V+W + P L+ YV++II HE Y+A + NDIAL+++ Sbjct: 59 RLIFGAKEVEWGTNKPVKPPLQE---RYVEKIIIHEKYSASSEANDIALMKITPPVTCGH 115 Query: 444 CELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS----NCSK 497 P +P P + Q TC V+GWG ++N R S LQ V LI N ++ Sbjct: 116 FIGPGCLPQFRAGPPRVPQ---TCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTR 172 Query: 498 FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMD-ANNVTYVWGVVSWGENCGKPEFP 556 +Y R + CAG +G ID C+GDSGGPL+C D A N V G+ SWG C + + P Sbjct: 173 WYNGRIRSTNV-CAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRP 231 Query: 557 GVYTKVANYFDWISYHVG 574 GVYT +Y +WI+ +G Sbjct: 232 GVYTSTWSYLNWIASKIG 249 >6AOD-C nrPDB Length = 245 Score = 131 bits (330), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 85/238 (35%), Positives = 125/238 (52%), Gaps = 15/238 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGIT---CGGIYIGGCWILTAAHCLRASKTHR-YQIWTT 395 IVGG + G+ PWQV + S CGG IG WILTAAHC ++ + ++++ Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 396 VVDWIHPDLKRIVIEY-VDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 454 ++ ++K + V II H+ Y DIAL++++ D + P S+P+ Sbjct: 61 ILQ--QSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKG 118 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN--CSKFYGNRFYEKEMECA 511 + C V+GWG K +++ +LQ ++ L++N C K Y +M CA Sbjct: 119 DRNVIYTD----CWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICA 174 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G +G DACKGD+GGPL C N V ++ G+ SWGE C + E PGVYT V Y DWI Sbjct: 175 GYREGGKDACKGDAGGPLSCKH-NEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 231 >3F6U-H nrPDB Length = 240 Score = 131 bits (329), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 84/253 (33%), Positives = 122/253 (48%), Gaps = 34/253 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG-ITCGGIYIGGCWILTAAHCLRASK----------TH 388 ++ GK + GD PWQV + D+ + CG + I W+LTAAHC+ SK Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLR 60 Query: 389 RYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPR 448 R++ W +D + + H NY+ T NDIAL+ + + +P Sbjct: 61 RWEKWELDLD-------------IKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPI 107 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWG----REKD--NERVFSLQWGEVKLI--SNCSKFYG 500 +P L Q +V+GWG REK+ R F L + ++ ++ + CS+ Sbjct: 108 CLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMS 167 Query: 501 NRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYT 560 N E M CAG DAC+GDSGGP+V + ++ G+VSWGE CG GVYT Sbjct: 168 NMVSEN-MLCAGILGDRQDACEGDSGGPMVA-SFHGTWFLVGLVSWGEGCGLLHNYGVYT 225 Query: 561 KVANYFDWISYHV 573 KV+ Y DWI H+ Sbjct: 226 KVSRYLDWIHGHI 238 >1YC0-A nrPDB Length = 283 Score = 131 bits (329), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 85/262 (32%), Positives = 132/262 (50%), Gaps = 13/262 (4%) Query: 324 KLSCGVKNRMH-IRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL 382 + +CG +++ R RI+GG + G PW AI C G + CW+++AAHC Sbjct: 19 RQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSF-CAGSLVHTCWVVSAAHCF 77 Query: 383 RASKTHRYQIWTTVVDWIHPDLKRIVIEY-VDRIIFHENYNA-GTYQNDIALIEMKKDGN 440 S R + + + + +++ I + Y+ +D+ LI +KK G+ Sbjct: 78 SHSPP-RDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGD 136 Query: 441 KKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CS 496 + P C+P F C ++GWG +N +S L+ V L+++ CS Sbjct: 137 RCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCS 196 Query: 497 --KFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPE 554 + YG M CAG +D DAC+GDSGGPL C + N V Y++G++SWG+ CG+ Sbjct: 197 SPEVYGADI-SPNMLCAGYFDCKSDACQGDSGGPLAC-EKNGVAYLYGIISWGDGCGRLH 254 Query: 555 FPGVYTKVANYFDWISYHVGRP 576 PGVYT+VANY DWI+ + P Sbjct: 255 KPGVYTRVANYVDWINDRIRPP 276 >1FIZ-A nrPDB Length = 263 Score = 130 bits (326), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 93/257 (36%), Positives = 127/257 (49%), Gaps = 30/257 (11%) Query: 340 IVGGKRAQLGDLPWQVAIK------DASGITCGGIYIGGCWILTAAHCLRASKT---HRY 390 +VGG A+ G PW V+++ + TCGGI + W+LTAAHC + K R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 391 QIWTTVVDW-----IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCE 445 V W + P L+ +V+ II HE Y +G NDIALI++ C Sbjct: 61 IFGANEVVWGSNKPVKPPLQE---RFVEEIIIHEKYVSGLEINDIALIKITPP---VPCG 114 Query: 446 LPRSIPACVP-WSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLIS----NCSKF 498 P P C+P + + TC V+GWG +EK +LQ V LI N +++ Sbjct: 115 -PFIGPGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRW 173 Query: 499 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMD-ANNVTYVWGVVSWGENCGKPEFPG 557 Y R + CAG G ID C+GDSGGPL+C D A N V G+ SWG C + + PG Sbjct: 174 YNGRIRSTNV-CAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPG 232 Query: 558 VYTKVANYFDWISYHVG 574 VYT Y +WI+ +G Sbjct: 233 VYTSTWPYLNWIASKIG 249 >3P8G-A nrPDB Length = 241 Score = 127 bits (320), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 80/246 (32%), Positives = 123/246 (50%), Gaps = 17/246 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKD-ASGITCGGIYIGGCWILTAAHCLRASKTHRYQ---IWTT 395 +VGG A G+ PWQV++ G CG I W+++AAHC + RY WT Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 396 VVDWIHPDLKR----IVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP 451 + +H +R + + RII H +N T+ DIAL+E++K P Sbjct: 61 FLG-LHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRP---- 115 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLI--SNCSKFYGNRFYEKEM 508 C+P + ++F V+GWG + LQ GE+++I + C + + M Sbjct: 116 ICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMM 175 Query: 509 ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDW 568 C G G +D+C+GDSGGPL ++A+ + GVVSWG+ C + PGVYT++ + DW Sbjct: 176 -CVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDW 234 Query: 569 ISYHVG 574 I + G Sbjct: 235 IKENTG 240 >2R0L-A nrPDB Length = 248 Score = 125 bits (313), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 81/245 (33%), Positives = 123/245 (50%), Gaps = 12/245 (4%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG + G PW AI C G + CW+++AAHC S R + + Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDSF-CAGSLVHTCWVVSAAHCFSHSPP-RDSVSVVLGQH 58 Query: 400 IHPDLKRIVIEY-VDRIIFHENYNA-GTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 + + +++ I + Y+ +D+ LI +KK G++ P C+P Sbjct: 59 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 118 Query: 458 PYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CS--KFYGNRFYEKEMECA 511 F C ++GWG +N +S L+ V L+++ CS + YG M CA Sbjct: 119 GSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADI-SPNMLCA 177 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 G +D DAC+GDSGGPL C + N V Y++G++SWG+ CG+ PGVYT+VANY DWI+ Sbjct: 178 GYFDCKSDACQGDSGGPLAC-EKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 236 Query: 572 HVGRP 576 + P Sbjct: 237 RIRPP 241 >5UGG-A nrPDB Length = 251 Score = 122 bits (307), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 82/255 (32%), Positives = 127/255 (49%), Gaps = 22/255 (8%) Query: 323 PKLSCGVKNRMHIRR--KRIVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAA 379 P CG K ++ ++ R+VGG A PWQV+++ G+ CGG I W+LTAA Sbjct: 4 PSFDCG-KPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAA 62 Query: 380 HCL-RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD 438 HCL ++ + Y++ ++ + IE V R+ + DIAL+++ Sbjct: 63 HCLEKSPRPSSYKVILGAHQEVNLEPHVQEIE-VSRLFLEPT------RKDIALLKLSSP 115 Query: 439 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CS 496 D + IPAC+P Y+ C ++GWG + L+ ++ +I N C+ Sbjct: 116 AVITD----KVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCN 171 Query: 497 K--FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPE 554 + F R E+ CAG G D+C+GDSGGPLVC + + + GV SWG C +P Sbjct: 172 RYEFLNGRVQSTEL-CAGHLAGGTDSCQGDSGGPLVCFEKDKYI-LQGVTSWGLGCARPN 229 Query: 555 FPGVYTKVANYFDWI 569 PGVY +V+ + WI Sbjct: 230 KPGVYVRVSRFVTWI 244 >3E0N-B nrPDB Length = 271 Score = 122 bits (306), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 84/249 (33%), Positives = 118/249 (47%), Gaps = 23/249 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS---KTHRYQIWTTV 396 I GG A G PWQV+I CGG + W+L+AAHC + + + ++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 +D D K + + II H +Y Q DIAL+++ + P S+PA Sbjct: 61 LDSYSEDAK---VSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS 117 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFS---LQWGEVKLIS--NCSKFYG-------NRFY 504 P C V+GWG + + + LQ EV LIS C+ Y F Sbjct: 118 FPNGLH----CTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFV 173 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVAN 564 +++M CAG +G DAC+GDSGGPL C + Y+ G+VSWG+ CG PGVYT ++ Sbjct: 174 QEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGARNRPGVYTLASS 232 Query: 565 YFDWISYHV 573 Y WI V Sbjct: 233 YASWIQSKV 241 >4DUR-A nrPDB Length = 791 Score = 122 bits (306), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 82/255 (32%), Positives = 127/255 (49%), Gaps = 22/255 (8%) Query: 323 PKLSCGVKNRMHIRR--KRIVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAA 379 P CG K ++ ++ R+VGG A PWQV+++ G+ CGG I W+LTAA Sbjct: 544 PSFDCG-KPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAA 602 Query: 380 HCL-RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD 438 HCL ++ + Y++ ++ + IE V R+ + DIAL+++ Sbjct: 603 HCLEKSPRPSSYKVILGAHQEVNLEPHVQEIE-VSRLFLEPT------RKDIALLKLSSP 655 Query: 439 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CS 496 D + IPAC+P Y+ C ++GWG + L+ ++ +I N C+ Sbjct: 656 AVITD----KVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCN 711 Query: 497 K--FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPE 554 + F R E+ CAG G D+C+GDSGGPLVC + + + GV SWG C +P Sbjct: 712 RYEFLNGRVQSTEL-CAGHLAGGTDSCQGDSGGPLVCFEKDKYI-LQGVTSWGLGCARPN 769 Query: 555 FPGVYTKVANYFDWI 569 PGVY +V+ + WI Sbjct: 770 KPGVYVRVSRFVTWI 784 >3DFJ-A nrPDB Length = 263 Score = 121 bits (303), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 84/249 (33%), Positives = 118/249 (47%), Gaps = 23/249 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS---KTHRYQIWTTV 396 I GG A G PWQV+I CGG + W+L+AAHC + + + ++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 +D D K + + II H +Y Q DIAL+++ + P S+PA Sbjct: 61 LDSYSEDAK---VSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANAS 117 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFS---LQWGEVKLIS--NCSKFYG-------NRFY 504 P C V+GWG + + + LQ EV LIS C+ Y F Sbjct: 118 FPNGLH----CTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFV 173 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVAN 564 +++M CAG +G DAC+GDSGGPL C + Y+ G+VSWG+ CG PGVYT ++ Sbjct: 174 QEDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGARNRPGVYTLASS 232 Query: 565 YFDWISYHV 573 Y WI V Sbjct: 233 YASWIQSKV 241 >3LC3-A nrPDB Length = 235 Score = 121 bits (303), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 83/237 (35%), Positives = 118/237 (49%), Gaps = 16/237 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS-KTHRYQIWTTVVD 398 +VGG+ A+ G PWQV + CGG + WI+TAAHC+ K + + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGT--YQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 H + KR VI RII H NYNA Y +DIAL+E+ ++ P C+ Sbjct: 61 TEHTEQKRNVI----RIIPHHNYNAAINKYNHDIALLEL----DEPLVLNSYVTPICIAD 112 Query: 457 SPY--LFQPNDTCIVSGWGREKDNER-VFSLQWGEVKLISNCSKFYGNRF-YEKEMECAG 512 Y +F + VSGWGR R LQ+ V L+ + +F M CAG Sbjct: 113 KEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAG 172 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 ++G D+C+GDSGGP V + +++ G++SWGE C G+YTKV+ Y +WI Sbjct: 173 FHEGGRDSCQGDSGGPHVT-EVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWI 228 >1BRU-P nrPDB Length = 241 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 85/244 (34%), Positives = 136/244 (55%), Gaps = 22/244 (9%) Query: 340 IVGGKRAQLGDLPWQVAIK-DASGI---TCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG+ A+ PWQV+++ D+SG TCGG + W+LTAAHC+ +S+T+R + Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQN--DIALIEMKKDGNKKDCELPRSIPAC 453 + P + V +++ H+++N+ N DIAL+++ + D + C Sbjct: 61 SLSTNEPGSLAV---KVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTD----KIQLGC 113 Query: 454 VPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLI--SNCSK--FYGNRFYEKEM 508 +P + + N C V+GWGR + N LQ G++ ++ + CSK ++G+ + M Sbjct: 114 LPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTV-KTNM 172 Query: 509 ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEF--PGVYTKVANYF 566 CAG DG I +C GDSGGPL C AN V G+VS+G + G + P V+T+V+NY Sbjct: 173 ICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYI 231 Query: 567 DWIS 570 DWI+ Sbjct: 232 DWIN 235 >4KKD-A nrPDB Length = 433 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 94/297 (31%), Positives = 141/297 (47%), Gaps = 41/297 (13%) Query: 316 RRIKSLLPKLSCGVKNR-MHIRRKRIVGGKRAQLGDLPWQ--VAIKDASGIT-----CGG 367 R + + LP+ CG +R + +RI+GG+ A+ G PWQ + ++D S + G Sbjct: 132 RSLPTCLPE--CGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSG 189 Query: 368 IYIGGCWILTAAHCLRASKTHRYQI-----WTTVVDWIHP--DLKRIVIEYVDRIIFHEN 420 + WILTAAH LR+ + I TV +H D V R++ H + Sbjct: 190 ALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPD 249 Query: 421 YNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN-- 478 +N Y +DIAL+++++ +P +P P P P+ +V+GWG N Sbjct: 250 FNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGP---APHMLGLVAGWGISNPNVT 306 Query: 479 --------ERVFS--LQWGEVKLI--SNCSKFY----GNRFYEKEMECAGTYDGSIDACK 522 R S LQ+ ++ ++ + C Y GN + M CAG Y+G D C Sbjct: 307 VDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCL 366 Query: 523 GDSGGPLVCMDANNVTYV-WGVVSWG--ENCGKPEFPGVYTKVANYFDWISYHVGRP 576 GDSG V D + +V G+VSWG E CG + GVYTKV+NY DW+ +G P Sbjct: 367 GDSGEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLP 423 >4DGJ-A nrPDB Length = 235 Score = 120 bits (301), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 119/236 (50%), Gaps = 12/236 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG A+ G PW V + + CG + W+++AAHC+ + WT ++ Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSK-WTAILGL 59 Query: 400 -IHPDL--KRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + +L + V +D I+ + +YN NDIA++ ++ N D P S+P Sbjct: 60 HMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPE---- 115 Query: 457 SPYLFQPNDTCIVSGWGRE-KDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 +F P C ++GWG LQ +V L+SN C + + M CAG Sbjct: 116 ENQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGY 175 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 +G ID+C+GDSGGPL+C + NN ++ GV S+G C P PGVY +V+ + +WI Sbjct: 176 EEGGIDSCQGDSGGPLMCQE-NNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWI 230 >5LHN-A nrPDB Length = 247 Score = 120 bits (300), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 84/252 (33%), Positives = 134/252 (53%), Gaps = 22/252 (8%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASG----ITCGGIYIGGCWILTAAHC-LRASKTHRYQI 392 IVGG+ ++ + PW AI K+ G CGG I CW+ +AAHC ++ K Y + Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 393 WTTVVDWIHPDLKRIVIEYVDRIIFHENY--NAGTYQNDIALIEMKKDGNKKDCELP-RS 449 + + + E V+++I HE Y ++ Y NDIAL++++ + C P RS Sbjct: 61 YLGQSKESSYNPGEMKFE-VEQLILHEYYREDSLAYHNDIALLKIRTSTGQ--CAQPSRS 117 Query: 450 IPACVPWSPYLFQP-NDTCIVSGWGREKDNERVF--SLQWGEVKLISN----CSKFYGNR 502 I + P C ++G+G+E +++ ++ +L+ VKL+S+ +YG+ Sbjct: 118 IQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSE 177 Query: 503 FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKV 562 K M CA + D+CKGDSGGPL+C T + G+VSWG C + PGVYT+V Sbjct: 178 INYK-MLCAADPEWKTDSCKGDSGGPLICNIEGRPT-LSGIVSWGRGCAEKNKPGVYTRV 235 Query: 563 ANYFDWISYHVG 574 +++ DWI H+G Sbjct: 236 SHFLDWIQSHIG 247 >4IGD-A nrPDB Length = 406 Score = 119 bits (299), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 90/283 (31%), Positives = 131/283 (46%), Gaps = 37/283 (13%) Query: 316 RRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCW 374 R + + LP CG+ +I G+ AQ G PW + +G CGG +G W Sbjct: 134 RSLPTCLP--VCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSW 191 Query: 375 ILTAAHCLRASKTHRYQIWTTVVDWIHP-DLKRIVIEY-------------VDRIIFHEN 420 I+TAAHCL S D + P D K I+ ++ V H Sbjct: 192 IVTAAHCLHQSLDPEDPTLRD-SDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQ 250 Query: 421 YNAGTYQNDIALIEMKKDGNKKDCELPR----SIPACVPWSPYLFQPNDTCIVSGWGREK 476 Y+ T++ND+AL+E+ E P +P C+P P Q IVSGWG++ Sbjct: 251 YDPNTFENDVALVEL--------LESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGKQF 300 Query: 477 DNERVFSLQWGEVKLI--SNCSKFYG--NRFYEKEMECAGTYDGSIDACKGDSGGPLVCM 532 +L E+ ++ S C K Y + ++M CAG +G DAC GDSGGP+V + Sbjct: 301 LQRFPETLMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTL 360 Query: 533 DANNVT-YVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 + Y+ G VSWG++CGK + GVY+ + + DWI G Sbjct: 361 NRERGQWYLVGTVSWGDDCGKKDRYGVYSYIHHNKDWIQRVTG 403 >3BSQ-A nrPDB Length = 227 Score = 119 bits (299), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 82/237 (34%), Positives = 113/237 (47%), Gaps = 26/237 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G G PWQVA+ + + CGG+ + W+LTAAHC K + Y + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA-CVPWSP 458 +RI + H Y+ T+ ND+ L+++ +P+ C P Sbjct: 57 GDRRAQRI---KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP--- 110 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTY 514 P TC VSGWG + F L +VKLIS +C+K Y + E M CAG Sbjct: 111 ----PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGIP 165 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWIS 570 D +AC GDSGGPLVC + G+VSWG CG+P PGVYT+V + WI+ Sbjct: 166 DSKKNACNGDSGGPLVCRGT-----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 217 >5ZFH-A nrPDB Length = 224 Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 84/239 (35%), Positives = 115/239 (48%), Gaps = 32/239 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G + + G PWQVA+ + + CGG+ + W+LTAAHC K +YQ+ Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHC----KMGQYQVQLGSDKI 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEM----KKDGNKKDCELPRSIPACVP 455 ++I + H Y+ T+ NDI L+ + K + +LP C P Sbjct: 57 GDQSAQKI---KATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEH---CEP 110 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECA 511 P +C VSGWG + F L +VKLIS+ C K Y + K M CA Sbjct: 111 -------PGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKD-LLGKTMLCA 162 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWI 569 G D + C GDSGGPLVC D + G+VSWG CG+P PGVYT+V Y W+ Sbjct: 163 GIPDSKTNTCNGDSGGPLVCNDT-----LQGLVSWGTYPCGQPNDPGVYTQVCKYKRWV 216 >4H4F-A nrPDB Length = 249 Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 89/243 (36%), Positives = 132/243 (54%), Gaps = 21/243 (8%) Query: 340 IVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG+ A+ PWQ++++ D TCGG I ++LTAAHC+ ++T+R + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP-ACV 454 ++ D + + VD I H+ +NA +NDIALI++ + EL +I AC+ Sbjct: 61 NLE--VEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH-----VELSDTIQVACL 113 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLI--SNCSK--FYGNRFYEKEME 509 P L + C V+GWGR N + LQ G ++ + CS+ ++G R +K M Sbjct: 114 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRV-KKTMV 172 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG--ENCGKPEFPGVYTKVANYFD 567 CAG DG I AC GDSGGPL C N V+G+VS+G C + P VYT+V+ Y D Sbjct: 173 CAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYID 231 Query: 568 WIS 570 WI+ Sbjct: 232 WIN 234 >1EKB-B nrPDB Length = 235 Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 116/236 (49%), Gaps = 12/236 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG ++ G PW VA+ CG + W+++AAHC+ + W V+ Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSK-WKAVLGL 59 Query: 400 -IHPDLKRIVIE--YVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + +L IE +D+I+ + +YN NDIA++ ++ N D P C+P Sbjct: 60 HMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTD----YIQPICLPE 115 Query: 457 SPYLFQPNDTCIVSGWGRE-KDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 +F P C ++GWG LQ +V L+SN C + + M CAG Sbjct: 116 ENQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGY 175 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G +D+C+GDSGGPL+C + NN + GV S+G C P PGVY +V + +WI Sbjct: 176 EAGGVDSCQGDSGGPLMCQE-NNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWI 230 >1SGF-G nrPDB Length = 237 Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 79/246 (32%), Positives = 117/246 (47%), Gaps = 33/246 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + + PW VA+ + CGG+ + W+LTAAHC + Y++W + Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDN----YKVWLGKNN- 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGT-----------YQNDIALIEMKKDGNKKDCELPR 448 + D +V + I H +N Y ND+ L+ + K + D P Sbjct: 56 LFKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPI 115 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFY 504 ++P P + TC+ SGWG + F+ L +KL+ N C+K + + Sbjct: 116 TLPTEEP------KLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVT 169 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVA 563 + M CAG DG D CKGDSGGPL+C + G+ SWG CG+P+ PGVYTK+ Sbjct: 170 D-AMLCAGEMDGGKDTCKGDSGGPLICDGV-----LQGITSWGHTPCGEPDMPGVYTKLN 223 Query: 564 NYFDWI 569 + WI Sbjct: 224 KFTSWI 229 >4IW4-E nrPDB Length = 279 Score = 116 bits (291), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 88/272 (32%), Positives = 129/272 (47%), Gaps = 38/272 (13%) Query: 340 IVGGKRAQLGDLPWQ--VAIKDASGIT-----CGGIYIGGCWILTAAHCLRASKTHRYQI 392 I+GG+ A+ G PWQ + ++D S + G + WILTAAH LR+ + I Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 393 -----WTTVVDWIHP--DLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCE 445 TV +H D V R++ H ++N Y +DIAL+++++ Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 446 LPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN----------ERVFS--LQWGEVKLI- 492 +P +P P P P+ +V+GWG N R S LQ+ ++ ++ Sbjct: 121 MPVCLPRLEPEGP---APHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVP 177 Query: 493 -SNCSKFY----GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYV-WGVVSW 546 + C Y GN + M CAG Y+G D C GDSGG V D + +V G+VSW Sbjct: 178 HAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSW 237 Query: 547 G--ENCGKPEFPGVYTKVANYFDWISYHVGRP 576 G E CG + GVYTKV+NY DW+ +G P Sbjct: 238 GGPEECGSKQVYGVYTKVSNYVDWVWEQMGLP 269 >4XDE-A nrPDB Length = 257 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 79/246 (32%), Positives = 114/246 (46%), Gaps = 13/246 (5%) Query: 338 KRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 + +VGG A G P+ A+ C G I CW+LTAAHCL+ Sbjct: 1 RSVVGGLVALRGAHPYIAALYWGHSF-CAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQ 59 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCEL--PRSIPACVP 455 + + + V HE ++ +YQ+D+AL+ +++D + C L P P +P Sbjct: 60 ERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGS-CALLSPYVQPVSLP 118 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS----NCSKFYGNRFYEKEME 509 C V+GWG + + ++ LQ +V +S + +G+ M Sbjct: 119 SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPG-ML 177 Query: 510 CAGTYDGSIDACKGDSGGPLVCMD--ANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFD 567 CAG +G DAC+GDSGGPLVC D A + G++SWG CG PGVYT VA Y Sbjct: 178 CAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLA 237 Query: 568 WISYHV 573 WI H Sbjct: 238 WIREHT 243 >4DJZ-B nrPDB Length = 251 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 85/259 (32%), Positives = 123/259 (47%), Gaps = 35/259 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 I G+ AQ G PW + +G CGG +G WI+TAAHCL S + D Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDS-D 59 Query: 399 WIHP-DLKRIVIEY-------------VDRIIFHENYNAGTYQNDIALIEMKKDGNKKDC 444 + P D K I+ ++ V H Y+ T++ND+AL+E+ Sbjct: 60 LLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVEL--------L 111 Query: 445 ELPR----SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI--SNCSKF 498 E P +P C+P P Q IVSGWG++ +L E+ ++ S C K Sbjct: 112 ESPVLNAFVMPICLPEGPQ--QEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHSTCQKA 169 Query: 499 YG--NRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVT-YVWGVVSWGENCGKPEF 555 Y + ++M CAG +G DAC GDSGGP+V ++ Y+ G VSWG++CGK + Sbjct: 170 YAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDR 229 Query: 556 PGVYTKVANYFDWISYHVG 574 GVY+ + + DWI G Sbjct: 230 YGVYSYIHHNKDWIQRVTG 248 >1Q3X-A nrPDB Length = 328 Score = 115 bits (289), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 89/260 (34%), Positives = 126/260 (48%), Gaps = 31/260 (11%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK 386 CG+ R RI GG++A+ GD PWQV I G T G + W+LTAAH + K Sbjct: 76 CGLSART--TGGRIYGGQKAKPGDFPWQVLI--LGGTTAAGALLYDNWVLTAAHAVYEQK 131 Query: 387 THRYQIWTTVVDWIHPDLKRIVIEYV----DRIIFHENY--NAGTYQNDIALIEMKKDGN 440 + +D LKR+ Y + + HE Y +AG + NDIALI++ N Sbjct: 132 HD-----ASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAG-FDNDIALIKL----N 181 Query: 441 KKDCELPRSIPACVPW--SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CS 496 K P C+P + + +D SGWG + +L + ++ ++ + C+ Sbjct: 182 NKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCT 241 Query: 497 KFYGNRFYEK-----EMECAGTYDGSIDACKGDSGGPLVCMDANNVT-YVWGVVSWGE-N 549 Y Y + M CAG G D+C+GDSGG LV +D+ +V G+VSWG N Sbjct: 242 AAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 301 Query: 550 CGKPEFPGVYTKVANYFDWI 569 CG+ GVYTKV NY WI Sbjct: 302 CGEAGQYGVYTKVINYIPWI 321 >1NPM-A nrPDB Length = 225 Score = 115 bits (288), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 81/237 (34%), Positives = 112/237 (47%), Gaps = 24/237 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G+ PWQ A+ + CGG+ +G W+LTAAHC K +Y + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLGDHSL 56 Query: 400 IHPDLKRIVIEYVDRIIF--HENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 D I+ I + N N + +DI LI ++ N D P + P Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCP-- 114 Query: 458 PYLFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 + CI+SGWG + F +L EVK+ S C + Y + E M CAG+ Sbjct: 115 ----KVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEG-MVCAGS 169 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 569 +G+ D C+GDSGGPLVC + G+ SWG + CGKPE PGVYTK+ Y WI Sbjct: 170 SNGA-DTCQGDSGGPLVCDG-----MLQGITSWGSDPCGKPEKPGVYTKICRYTTWI 220 >4MPW-A nrPDB Length = 245 Score = 115 bits (288), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 85/259 (32%), Positives = 121/259 (46%), Gaps = 39/259 (15%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGI---TCGGIYIGGCWILTAAHC-------LRASKTHR 389 IVGG+ A PWQV+++ CGG I W+LTAAHC L A + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 390 YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRS 449 + D + P V RII H + DIAL+E+++ + Sbjct: 61 REQHLYYQDQLLP---------VSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVT 111 Query: 450 IPACVPWSPYLFQPNDTCIVSGWGREKDNERV---FSLQWGEVKLISN--------CSKF 498 +P + F P C V+GWG ++ER+ F L+ +V ++ N + Sbjct: 112 LPP----ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAY 167 Query: 499 YGN--RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFP 556 G+ R +M CAG + D+C+GDSGGPLVC N GVVSWGE C +P P Sbjct: 168 TGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRP 224 Query: 557 GVYTKVANYFDWISYHVGR 575 G+YT+V Y DWI ++V + Sbjct: 225 GIYTRVTYYLDWIHHYVPK 243 >1X7A-C nrPDB Length = 235 Score = 115 bits (287), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 79/236 (33%), Positives = 115/236 (48%), Gaps = 14/236 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG+ A+ G PWQV + CGG I W++TAAHC+ + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNA--GTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 P +R V R I H +YNA Y +DIAL+E+ + P C+ Sbjct: 61 TEPTEQR---RNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNS----YVTPICIADK 113 Query: 458 PY--LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRF-YEKEMECAGT 513 Y +F + VSGWGR + R + LQ+ +V L+ + +F M CAG Sbjct: 114 EYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGF 173 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 ++G D+C+GDSGGP V + +++ G++SWGE C G+YTKV+ Y +WI Sbjct: 174 HEGGKDSCQGDSGGPHVT-EVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWI 228 >1LTO-A nrPDB Length = 245 Score = 114 bits (286), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 89/259 (34%), Positives = 125/259 (48%), Gaps = 39/259 (15%) Query: 340 IVGGKRAQLGDLPWQVA--IKDASGIT-CGGIYIGGCWILTAAHCL----RASKTHRYQI 392 IVGG+ A PWQV+ ++D + CGG I W+LTAAHCL + T R Q+ Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 393 WTTVV---DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRS 449 + D + P V RII H + DIAL+E+++ N R Sbjct: 61 REQHLYYQDQLLP---------VSRIIVHPQFYIIQTGADIALLELEEPVNISS----RV 107 Query: 450 IPACVPWSPYLFQPNDTCIVSGWGREKDNERV---FSLQWGEVKLISN--------CSKF 498 +P + F P C V+GWG ++E + F L+ +V ++ N + Sbjct: 108 HTVMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAY 167 Query: 499 YGN--RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFP 556 G+ R +M CAG + D+CKGDSGGPLVC N GVVSW E C +P P Sbjct: 168 TGDDVRIIRDDMLCAG--NSQRDSCKGDSGGPLVC-KVNGTWLQAGVVSWDEGCAQPNRP 224 Query: 557 GVYTKVANYFDWISYHVGR 575 G+YT+V Y DWI ++V + Sbjct: 225 GIYTRVTYYLDWIHHYVPK 243 >2F91-A nrPDB Length = 237 Score = 114 bits (286), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 79/241 (32%), Positives = 118/241 (48%), Gaps = 20/241 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDA----SGITCGGIYIGGCWILTAAHCLRASKTHR---YQI 392 IVGG A LG+ P+Q++ ++ S CG + +TA HC+ QI Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 393 WTTVVDW-IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP 451 +D ++ ++I+ V +II HEN++ NDI+L+++ D P ++P Sbjct: 61 VAGELDMSVNEGSEQIIT--VSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALP 118 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEM 508 IV+GWG + LQ V L+S+ C YG M Sbjct: 119 E------QGHTATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSM 172 Query: 509 ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDW 568 CAG +G D+C+GDSGGPL D + TY+ G+VSWG C +P +PGVYT+V+ + DW Sbjct: 173 ICAGVPEGGKDSCQGDSGGPLAASDTGS-TYLAGIVSWGYGCARPGYPGVYTEVSYHVDW 231 Query: 569 I 569 I Sbjct: 232 I 232 >5MS3-A nrPDB Length = 228 Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 79/243 (32%), Positives = 120/243 (49%), Gaps = 26/243 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG Q PWQ A+ + CGG+ +GG W+LTAAHC + T R ++ + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGD-HSLQNK 59 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAG---TYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 P+ + V++ I H YN+ + +D+ L++++ + P S+ Sbjct: 60 DGPEQEIPVVQS----IPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL------ 109 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLISN--CSKFYGNRFYEKEMECAG 512 + + QP C VSGWG F +L EVK+ C Y + + M CAG Sbjct: 110 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG-MVCAG 168 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISY 571 + G+ D C+GDSGGPLVC A + G+ SWG + CG+ + PGVYT + Y DWI Sbjct: 169 SSKGA-DTCQGDSGGPLVCDGA-----LQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 222 Query: 572 HVG 574 +G Sbjct: 223 IIG 225 >1ZJK-A nrPDB Length = 403 Score = 114 bits (284), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 88/260 (33%), Positives = 126/260 (48%), Gaps = 31/260 (11%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK 386 CG+ R +I GG++A+ GD PWQV I G T G + W+LTAAH + K Sbjct: 151 CGLSART--TGGQIYGGQKAKPGDFPWQVLI--LGGTTAAGALLYDNWVLTAAHAVYEQK 206 Query: 387 THRYQIWTTVVDWIHPDLKRIVIEYV----DRIIFHENY--NAGTYQNDIALIEMKKDGN 440 + +D LKR+ Y + + HE Y +AG + NDIALI++ N Sbjct: 207 HD-----ASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAG-FDNDIALIKL----N 256 Query: 441 KKDCELPRSIPACVPW--SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CS 496 K P C+P + + +D SGWG + +L + ++ ++ + C+ Sbjct: 257 NKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCT 316 Query: 497 KFYGNRFYEK-----EMECAGTYDGSIDACKGDSGGPLVCMDANNVT-YVWGVVSWGE-N 549 Y Y + M CAG G D+C+GDSGG LV +D+ +V G+VSWG N Sbjct: 317 AAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 376 Query: 550 CGKPEFPGVYTKVANYFDWI 569 CG+ GVYTKV NY WI Sbjct: 377 CGEAGQYGVYTKVINYIPWI 396 >4AN7-A nrPDB Length = 231 Score = 112 bits (281), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 78/239 (32%), Positives = 115/239 (48%), Gaps = 30/239 (12%) Query: 339 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 +IVGG +P+QV++ S CGG I W+++AAHC ++ R + +D Sbjct: 8 KIVGGYTCAANSIPYQVSLNSGSHF-CGGSLINSQWVVSAAHCYKSRIQVR--LGEHNID 64 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKK----DGNKKDCELPRSIPACV 454 + + + I +II H N+N T NDI LI++ + LPRS A Sbjct: 65 VLEGNEQFI---NAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAA- 120 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMEC 510 C++SGWG K + + LQ + ++S+ C Y + M C Sbjct: 121 ---------GTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQI-TGNMIC 170 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G +G D+C+GDSGGP+VC + G+VSWG C + PGVYTKV NY +WI Sbjct: 171 VGFLEGGKDSCQGDSGGPVVCNGQ-----LQGIVSWGYGCAQKNKPGVYTKVCNYVNWI 224 >1SC8-U nrPDB Length = 262 Score = 112 bits (281), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 83/266 (31%), Positives = 130/266 (48%), Gaps = 23/266 (8%) Query: 324 KLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAI---KDASGIT--CGGIYIGGCWILTA 378 K CG K R +I+GG+ + + PW AI +T CGG I CW+++A Sbjct: 2 KFQCGQKTLR--PRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISA 59 Query: 379 AHC-LRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGT--YQNDIALIEM 435 HC + K Y ++ + E V+ +I H++Y+A T + NDIAL+++ Sbjct: 60 THCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFE-VENLILHKDYSADTLAHHNDIALLKI 118 Query: 436 KKDGNKKDCELPRSIPACVPWSPYLFQPN--DTCIVSGWGREKDNERVF--SLQWGEVKL 491 + + C P + P +C ++G+G+E + ++ L+ VKL Sbjct: 119 RSKEGR--CAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKL 176 Query: 492 ISN--CSK--FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG 547 IS+ C + +YG+ K M CA D+C+GDSGGPLVC +T G+VSWG Sbjct: 177 ISHRECQQPHYYGSEVTTK-MLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLT-GIVSWG 234 Query: 548 ENCGKPEFPGVYTKVANYFDWISYHV 573 C + PGVYT+V+++ WI H Sbjct: 235 RGCALKDKPGVYTRVSHFLPWIRSHT 260 >6BQM-A nrPDB Length = 506 Score = 112 bits (281), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 78/263 (29%), Positives = 124/263 (47%), Gaps = 58/263 (22%) Query: 339 RIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 RI+GG++A G+ P+ VA+ +++S + CGG Y+GG ++LTAAHC+ + + Sbjct: 10 RIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVLLGA 69 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD------------------ 438 D D+ +V +I H +Y + NDIA++E+++D Sbjct: 70 FDM--NDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDFNEL 127 Query: 439 -----------GNKKDCELPRSIPACVPWSPYL-FQPNDTCIVSGWGREKDNERVFSLQW 486 GN+K+ + +S PA + + F P C G ++ N Sbjct: 128 TKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKN-------- 179 Query: 487 GEVKLISNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSW 546 N S+ N F CAG++ DAC GD+GGP + D+NN GVVSW Sbjct: 180 -------NYSQLTNNAF------CAGSF--GKDACSGDAGGP-IFFDSNNGRKQMGVVSW 223 Query: 547 GENCGKPEFPGVYTKVANYFDWI 569 G+ CG+ PGVYT ++ + DW+ Sbjct: 224 GDGCGRANSPGVYTNLSVFNDWL 246 >1FXY-A nrPDB Length = 228 Score = 112 bits (280), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 79/235 (33%), Positives = 117/235 (49%), Gaps = 20/235 (8%) Query: 340 IVGGKRAQLGDLPWQ-VAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IVGG + G++PWQ + I + + CGG + +ILTAAHCL +K R+++ + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAK--RFKVRVGDRN 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + V E V+ +I H + TY DIA++ +K + P S+P P + Sbjct: 59 TEQEEGGEAVHE-VEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPAT- 116 Query: 459 YLFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 C++SGWG + + LQ + ++S C Y + M C G Sbjct: 117 -----GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TSNMFCVGFL 170 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 +G D+C+GDSGGP+VC + GVVSWG+ C + PGVYTKV NY WI Sbjct: 171 EGGKDSCQGDSGGPVVCNGQ-----LQGVVSWGDGCAQKNKPGVYTKVYNYVKWI 220 >4FXG-H nrPDB Length = 242 Score = 110 bits (276), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 84/247 (34%), Positives = 121/247 (48%), Gaps = 29/247 (11%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I GG++A+ GD PWQV I G T G + W+LTAAH + K + +D Sbjct: 1 IYGGQKAKPGDFPWQVLI--LGGTTAAGALLYDNWVLTAAHAVYEQKHD-----ASALDI 53 Query: 400 IHPDLKRIVIEYV----DRIIFHENY--NAGTYQNDIALIEMKKDGNKKDCELPRSIPAC 453 LKR+ Y + + HE Y +AG + NDIALI++ N K P C Sbjct: 54 RMGTLKRLSPHYTQAWSEAVFIHEGYTHDAG-FDNDIALIKL----NNKVVINSNITPIC 108 Query: 454 VPW--SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEK--- 506 +P + + +D SGWG + +L + ++ ++ + C+ Y Y + Sbjct: 109 LPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSV 168 Query: 507 --EMECAGTYDGSIDACKGDSGGPLVCMDANNVT-YVWGVVSWGE-NCGKPEFPGVYTKV 562 M CAG G D+C+GD+GG LV +D+ +V G+VSWG NCG+ GVYTKV Sbjct: 169 TANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKV 228 Query: 563 ANYFDWI 569 NY WI Sbjct: 229 INYIPWI 235 >4NFE-A nrPDB Length = 237 Score = 110 bits (274), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 86/252 (34%), Positives = 115/252 (45%), Gaps = 45/252 (17%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + PWQVA+ CGG+ + W+LTAAHCL+ + Q+W + Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNS----QVWLGRHNL 56 Query: 400 IHPD--LKRIVIEYVDRIIFHENYNAGTYQ-----------NDIALIEMKKDGNKKDC-- 444 P+ +R+ + + H YN + +D+ L+ + + D Sbjct: 57 FEPEDTGQRVPVSHS---FPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVK 113 Query: 445 --ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLISN--CSKF 498 LP PA TC SGWG + E R SLQ + L+SN C++ Sbjct: 114 VLGLPTQEPAL----------GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARA 163 Query: 499 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPG 557 Y + E M CAG + G D C GDSGGPLVC N V G+ SWG E C PE P Sbjct: 164 YSEKVTEF-MLCAGLWTGGKDTCGGDSGGPLVC---NGVLQ--GITSWGPEPCALPEKPA 217 Query: 558 VYTKVANYFDWI 569 VYTKV +Y WI Sbjct: 218 VYTKVVHYRKWI 229 >2CGA-A nrPDB Length = 245 Score = 109 bits (273), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 80/251 (31%), Positives = 121/251 (48%), Gaps = 21/251 (8%) Query: 327 CGVKNRMHIRR--KRIVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLR 383 CGV + RIV G+ A G PWQV+++D +G CGG I W++TAAHC Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC-- 58 Query: 384 ASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKD 443 T + D ++I + ++ + YN+ T NDI L+++ + Sbjct: 59 -GVTTSDVVVAGEFD-QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAAS--- 113 Query: 444 CELPRSIPA-CVPWSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISN--CSKF 498 +++ A C+P + F TC+ +GWG R + LQ + L+SN C K+ Sbjct: 114 --FSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKY 171 Query: 499 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV 558 +G + + M CAG + +C GDSGGPLVC T V G+VSWG + PGV Sbjct: 172 WGTKIKD-AMICAGA--SGVSSCMGDSGGPLVCKKNGAWTLV-GIVSWGSSTCSTSTPGV 227 Query: 559 YTKVANYFDWI 569 Y +V +W+ Sbjct: 228 YARVTALVNWV 238 >1KIG-H nrPDB Length = 241 Score = 109 bits (273), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 79/237 (33%), Positives = 118/237 (49%), Gaps = 16/237 (6%) Query: 340 IVGGKRAQLGDLPWQ-VAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IVGG+ G+ PWQ + + + + CGG + ++LTAAHCL +K R+ + + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAK--RFTVRVGDRN 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSI-PACVP-- 455 + + E V+ + H + TY DIA++ +K R++ PAC+P Sbjct: 59 TEQEEGNEMAHE-VEMTVKHSRFVKETYDFDIAVLRLKTP-----IRFRRNVAPACLPEK 112 Query: 456 -WSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCS-KFYGNRFYEKEMECAG 512 W+ T IVSG+GR + R+ S L+ EV + + K + M CAG Sbjct: 113 DWAEATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAG 172 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 DAC+GDSGGP V + +V G+VSWGE C + GVYTKV+N+ WI Sbjct: 173 YDTQPEDACQGDSGGPHVTR-FKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWI 228 >5FXL-A nrPDB Length = 246 Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 73/235 (31%), Positives = 113/235 (48%), Gaps = 22/235 (9%) Query: 339 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 +IVGG +P+QV++ CGG I W+++AAHC ++ R + ++ Sbjct: 23 KIVGGYTCGANTVPYQVSLNSGYHF-CGGSLINSQWVVSAAHCYKSGIQVR--LGEDNIN 79 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + + I + I H +YN+ T NDI LI++K + S+P Sbjct: 80 VVEGNEQFI---SASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA--- 133 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 C++SGWG K + + L+ + ++S+ C Y + M CAG Sbjct: 134 ---SAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQI-TSNMFCAGYL 189 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 +G D+C+GDSGGP+VC + G+VSWG C + PGVYTKV NY WI Sbjct: 190 EGGKDSCQGDSGGPVVCSGK-----LQGIVSWGSGCAQKNKPGVYTKVCNYVSWI 239 >1C5M-D nrPDB Length = 255 Score = 109 bits (272), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 80/236 (33%), Positives = 117/236 (49%), Gaps = 14/236 (5%) Query: 340 IVGGKRAQLGDLPWQ-VAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IVGG+ + G+ PWQ + I + + CGG + +ILTAAHCL +K R+++ + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAK--RFKVRVGDRN 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP--- 455 + V E V+ +I H + TY DIA++ +K + PAC+P Sbjct: 59 TEQEEGGEAVHE-VEVVIKHNRFTKETYDFDIAVLRLKTPITFR----MNVAPACLPERD 113 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLIS-NCSKFYGNRFYEKEMECAGT 513 W+ T IVSG+GR + R + L+ EV + N K + + M CAG Sbjct: 114 WAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGY 173 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 DAC+GDSGGP V + +V G+VSWGE C + G+YTKV + WI Sbjct: 174 DTKQEDACQGDSGGPHVTR-FKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWI 228 >1ELV-A nrPDB Length = 333 Score = 108 bits (269), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 81/264 (30%), Positives = 119/264 (45%), Gaps = 34/264 (12%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK 386 CGV ++RI+GG A + + PWQV + GG I W+LTAAH + ++ Sbjct: 70 CGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNR 126 Query: 387 THRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNA-------GTYQNDIALIEMKKDG 439 + +T V L + + + + H + + NDIAL+ + KD Sbjct: 127 EPTMYVGSTSVQTSR--LAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRL-KDP 183 Query: 440 NKKDCELPRSIPACVPW--SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKL--ISNC 495 K P P C+P S Y D ++SGWGR + +R L+ + + + C Sbjct: 184 VKMG---PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKC 240 Query: 496 SKFYGNR--------FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVT--YVWGVVS 545 + + + M CAG G +D+CKGDSGG D N+ T Y G+VS Sbjct: 241 KEVKVEKPTADAEAYVFTPNMICAGGEKG-MDSCKGDSGGAFAVQDPNDKTKFYAAGLVS 299 Query: 546 WGENCGKPEFPGVYTKVANYFDWI 569 WG CG G+YT+V NY DWI Sbjct: 300 WGPQCGT---YGLYTRVKNYVDWI 320 >1PYT-D nrPDB Length = 251 Score = 107 bits (268), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 88/256 (34%), Positives = 133/256 (51%), Gaps = 22/256 (8%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCL 382 CG R+VGG+ A PWQ++++ + TCGG I +LTAAHC+ Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 383 RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKK 442 + T+R + ++ + + + + VD I HE +N+ +NDIALI++ + Sbjct: 61 SNTLTYRVALGKNNLE-VEDEAGSLYVG-VDTIFVHEKWNSFLVRNDIALIKLAET---- 114 Query: 443 DCELPRSIP-ACVPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLI--SNCSK- 497 EL +I AC+P L + C V+GWGR N + + LQ G ++ + CS+ Sbjct: 115 -VELGDTIQVACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQR 173 Query: 498 -FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE--NCGKPE 554 ++G E M CAG DG I AC GDSGGPL C A+ V G+VS+G +C + Sbjct: 174 DWWGTTVKET-MVCAGG-DGVISACNGDSGGPLNCQ-ADGQWDVRGIVSFGSGLSCNTFK 230 Query: 555 FPGVYTKVANYFDWIS 570 P V+T+V+ Y DWI+ Sbjct: 231 KPTVFTRVSAYIDWIN 246 >4J1Y-A nrPDB Length = 397 Score = 105 bits (263), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 80/264 (30%), Positives = 117/264 (44%), Gaps = 34/264 (12%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK 386 CGV + R +GG A + + PWQV + GG I W+LTAAH + ++ Sbjct: 134 CGVPREPFEEKARAIGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNR 190 Query: 387 THRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNA-------GTYQNDIALIEMKKDG 439 + +T V L + + + + H + + NDIAL+ +K D Sbjct: 191 EPTMYVGSTSVQTSR--LAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLK-DP 247 Query: 440 NKKDCELPRSIPACVPW--SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKL--ISNC 495 K P P C+P S Y D ++SGWGR + +R L+ + + + C Sbjct: 248 VKMG---PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKC 304 Query: 496 SKFYGNR--------FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVT--YVWGVVS 545 + + + M CAG G +D+CKGDSGG D N+ T Y G+VS Sbjct: 305 KEVKVEKPTADAEAYVFTPNMICAGGEKG-MDSCKGDSGGAFAVQDPNDKTKFYAAGLVS 363 Query: 546 WGENCGKPEFPGVYTKVANYFDWI 569 WG CG G+YT+V NY DWI Sbjct: 364 WGPQCGT---YGLYTRVKNYVDWI 384 >1F7Z-A nrPDB Length = 233 Score = 105 bits (262), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 116/239 (48%), Gaps = 32/239 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG Q +P+QV++ CGG I W+++AAHC ++ R + ++ Sbjct: 11 IVGGYTCQENSVPYQVSLNSGYHF-CGGSLINDQWVVSAAHCYKSRIQVR--LGEHNINV 67 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEM----KKDGNKKDCELPRSIPACVP 455 + + + + +II H N++ T NDI LI++ K + LP S C P Sbjct: 68 LEGNEQFV---NAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSS---CAP 121 Query: 456 WSPYLFQPNDTCIVSGWGREKD---NERVFSLQWGEVKLI--SNCSKFYGNRFYEKEMEC 510 C++SGWG NE LQ + L+ ++C Y + + M C Sbjct: 122 -------AGTQCLISGWGNTLSSGVNEPDL-LQCLDAPLLPQADCEASYPGKITDN-MVC 172 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G +G D+C+GDSGGP+VC + G+VSWG C P+ PGVYTKV NY DWI Sbjct: 173 VGFLEGGKDSCQGDSGGPVVCNGE-----LQGIVSWGYGCALPDNPGVYTKVCNYVDWI 226 >6QHB-A nrPDB Length = 223 Score = 105 bits (261), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 69/221 (31%), Positives = 105/221 (47%), Gaps = 20/221 (9%) Query: 352 PWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEY 411 P+Q A+ + + CGG+ I W+LTAAHC K Q++ + + Sbjct: 13 PYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHN-LGQQESSQEQSS 67 Query: 412 VDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSG 471 V R + H +Y+A ++ DI L+ + + + P +P +C + G Sbjct: 68 VVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP------LPLERDCSAQTTSCHILG 121 Query: 472 WGREKDNERVFSLQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPL 529 WG+ D + ++Q + L+S C Y + + M CAG D+C+GDSGGPL Sbjct: 122 WGKTADGDFPDTIQCAYIHLVSREECEHAYPGQI-TQNMLCAGDEKYGKDSCQGDSGGPL 180 Query: 530 VCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWI 569 VC D ++ G+VSWG CG E PGVYT V Y +WI Sbjct: 181 VCGD-----HLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 216 >1A0J-A nrPDB Length = 223 Score = 104 bits (260), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 116/235 (49%), Gaps = 22/235 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + +Q +++ CGG I W+++AAHC ++ R Q+ + Sbjct: 1 IVGGYECRKNSASYQASLQSGYHF-CGGSLISSTWVVSAAHCYKS----RIQVRLGEHNI 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + I+ V ++I H +YN+ NDI LI++ K + ++P+ S Sbjct: 56 AVNEGTEQFIDSV-KVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASS-- 112 Query: 460 LFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C+VSGWG + + +L+ ++ ++S+ C+ Y + M CAG + Sbjct: 113 ----GTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQI-TSNMFCAGFME 167 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 G D+C+GDSGGP+VC + GVVSWG C + PGVYTKV NY WIS Sbjct: 168 GGKDSCQGDSGGPVVCNGQ-----LQGVVSWGYGCAQRNKPGVYTKVCNYRSWIS 217 >4Z6A-H nrPDB Length = 249 Score = 103 bits (258), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 77/236 (32%), Positives = 105/236 (44%), Gaps = 12/236 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGGK G+ PWQV + CGG I W+++AAHC K R I Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP---W 456 + V ++I Y GT +DIAL+ + + D +P C+P + Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTD----HVVPLCLPERTF 116 Query: 457 SPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVK--LISNCSKFYGNRFYEKEMECAGT 513 S +VSGWG+ D L V + +C Y + E M CAG Sbjct: 117 SERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEY-MFCAGY 175 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 DGS D+CKGDSGGP Y+ G+VSWG+ C GVYT+V+ Y +W+ Sbjct: 176 SDGSKDSCKGDSGGPH-ATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWL 230 >1SGF-A nrPDB Length = 240 Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 73/234 (31%), Positives = 108/234 (46%), Gaps = 33/234 (14%) Query: 352 PWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEY 411 PW VA+ + CGG+ + W+LTAAHC +YQ+W +++ D Sbjct: 16 PWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYN----DKYQVWLGKNNFLE-DEPSDQHRL 70 Query: 412 VDRIIFHENYNAG-----------TYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYL 460 V + I H ++N Y ND+ L+ + K + D P ++P P Sbjct: 71 VSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEP----- 125 Query: 461 FQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDG 516 + TC+ SGWG + + LQ +KL+ N C K + + + M CAG DG Sbjct: 126 -KLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDA-MLCAGEMDG 183 Query: 517 SIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWI 569 C+ DSGGPL+C + G+ SWG E CG+P P VYTK+ + WI Sbjct: 184 GSYTCEHDSGGPLIC-----DGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWI 232 >3QUM-P nrPDB Length = 237 Score = 102 bits (255), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 112/250 (44%), Gaps = 41/250 (16%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + PWQV + CGG+ + W+LTAAHC+R ++ I Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSVILLGRHSL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQN-----------DIALIEMKKDGNKKDC---- 444 HP+ V + V H Y+ +N D+ L+ + + D Sbjct: 57 FHPEDTGQVFQ-VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 115 Query: 445 ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYG 500 +LP PA TC SGWG + E + LQ ++ +ISN C++ + Sbjct: 116 DLPTQEPAL----------GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHP 165 Query: 501 NRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVY 559 + K M CAG + G C GDSGGPLVC N V + G+ SWG E C PE P +Y Sbjct: 166 QKV-TKFMLCAGRWTGGKSTCSGDSGGPLVC---NGV--LQGITSWGSEPCALPERPSLY 219 Query: 560 TKVANYFDWI 569 TKV +Y WI Sbjct: 220 TKVVHYRKWI 229 >5UBM-A nrPDB Length = 252 Score = 102 bits (254), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 114/252 (45%), Gaps = 34/252 (13%) Query: 339 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 RI+GG A + + PWQV + GG I W+LTAAH + ++ + +T V Sbjct: 1 RIIGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNA-------GTYQNDIALIEMKKDGNKKDCELPRSIP 451 L + + + + H + + NDIAL+ +K D K P P Sbjct: 58 --TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLK-DPVKMG---PTVSP 111 Query: 452 ACVPW--SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKL--ISNCSKFYGNR----- 502 C+P S Y D ++SGWGR + +R L+ + + + C + + Sbjct: 112 ICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 503 ---FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVT--YVWGVVSWGENCGKPEFPG 557 + M CAG G +D+CKGDSGG D N+ T Y G+VSWG CG G Sbjct: 172 EAYVFTPNMICAGGEKG-MDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT---YG 227 Query: 558 VYTKVANYFDWI 569 +YT+V NY DWI Sbjct: 228 LYTRVKNYVDWI 239 >2BDH-A nrPDB Length = 223 Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 73/237 (30%), Positives = 110/237 (46%), Gaps = 19/237 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G+ PWQ A+ + + C G+ + W+L+AAHC + S T + + D Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 P + + R H YN ND+ LI++ + ++ D SI + P + Sbjct: 61 -EPGSQMVEASLSVR---HPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA-- 114 Query: 460 LFQPNDTCIVSGWGREKDNERVFSLQ--WGEVKLISNCSKFYGNRFYEKEMECAGTYDGS 517 ++C+VSGWG + LQ V CSK Y + Y M CAG Sbjct: 115 ----GNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGQDQ 169 Query: 518 IDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHV 573 D+C GDSGGPL+C Y+ G+VS+G+ CG+ PGVYT + + +WI V Sbjct: 170 KDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 221 >2TLD-E nrPDB Length = 220 Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 74/234 (31%), Positives = 112/234 (47%), Gaps = 25/234 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG +P+QV++ CGG I W+++AAHC ++ R + ++ Sbjct: 1 IVGGYTCGANTVPYQVSLNSGYHF-CGGSLINSQWVVSAAHCYKSGIQVR--LGEDNINV 57 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + + I + I H +YN+ T NDI LI++K + S+P Sbjct: 58 VEGNEQFI---SASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA---- 110 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C++SGWG K + + L+ + ++S+ C Y + M CAG Sbjct: 111 --SAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQI-TSNMFCAGLEG 167 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G D+C+GDSGGP+VC + G+VSWG C K + PGVYTKV NY WI Sbjct: 168 G--DSCQGDSGGPVVCSGK-----LQGIVSWGSGCAKNK-PGVYTKVCNYVSWI 213 >1UTJ-A nrPDB Length = 242 Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 111/241 (46%), Gaps = 33/241 (13%) Query: 339 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS-----KTHRYQIW 393 +IVGG + P QV++ CGG + W+++AAHC ++ H ++ Sbjct: 20 KIVGGYECKPYSQPHQVSLNSGYHF-CGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKVT 78 Query: 394 TTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP-A 452 +I R+I H NY++ NDI LI++ K P ++P + Sbjct: 79 EGSEQFISSS----------RVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPTS 128 Query: 453 CVPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLIS--NCSKFYGNRFYEKEME 509 C P C VSGWG + + LQ + ++S +C+ Y M Sbjct: 129 CAP-------AGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGMI-TNAMF 180 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 CAG +G D+C+GDSGGP+VC + GVVSWG C +P PGVY KV + DW+ Sbjct: 181 CAGYLEGGKDSCQGDSGGPVVCNGE-----LQGVVSWGYGCAEPGNPGVYAKVCIFNDWL 235 Query: 570 S 570 + Sbjct: 236 T 236 >2B9L-A nrPDB Length = 394 Score = 100 bits (248), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 74/267 (27%), Positives = 118/267 (44%), Gaps = 30/267 (11%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGI--------TCGGIYIGGCWILTA 378 CG++N + K A+ G+ PW VA+ A+ I CGG I +LT Sbjct: 118 CGIRNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTG 177 Query: 379 AHCLRASKTHRYQIWTTVVDW-IHPDLKRIVIE--YVDRIIFHENYNAGTYQNDIALIEM 435 AHC+ + +++ I +W + +R+ + + ++I H N+N T ND+AL+ + Sbjct: 178 AHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLL 237 Query: 436 KKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNER------VFSLQWGEV 489 + + D C+P +F + C SGWG+++ R + +Q V Sbjct: 238 DRPLVQAD----NIGTICLPQQSQIFDSTE-CFASGWGKKEFGSRHRYSNILKKIQLPTV 292 Query: 490 KLISNCSKFYGNRF-----YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVT--YVWG 542 + R ++ CAG G D C GD G PL C D N + G Sbjct: 293 DRDKCQADLRNTRLGLKFVLDQTFVCAGGEQGK-DTCTGDGGSPLFCPDPRNPSRYMQMG 351 Query: 543 VVSWGENCGKPEFPGVYTKVANYFDWI 569 +V+WG CG PGVY VA++ +WI Sbjct: 352 IVAWGIGCGDENVPGVYANVAHFRNWI 378 >5C67-A nrPDB Length = 224 Score = 98.2 bits (243), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 104/247 (42%), Gaps = 48/247 (19%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS-----KTHRYQIWT 394 IVGG + LP+QV++ S CGG I W+++AAHC + H ++ Sbjct: 1 IVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKK----DGNKKDCELPRSI 450 +I+ +II H YN T NDI LI++ + LP + Sbjct: 60 GNEQFIN----------AAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAP 109 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQW--------GEVKLISNCSKFYGNR 502 PA C++SGWG N F + V + C Y + Sbjct: 110 PAA----------GTECLISGWG----NTLSFGADYPDELKCLDAPVLTQAECKASYPGK 155 Query: 503 FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKV 562 M C G +G D+C+ D+GGP+VC + GVVSWG C PGVYTKV Sbjct: 156 I-TNSMFCVGFLEGGKDSCQRDAGGPVVCNGQ-----LQGVVSWGHGCAWKNRPGVYTKV 209 Query: 563 ANYFDWI 569 NY DWI Sbjct: 210 YNYVDWI 216 >5KWM-A nrPDB Length = 230 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 71/246 (28%), Positives = 113/246 (45%), Gaps = 24/246 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWT--TV 396 IVGG+ A + D P+ VA+ G CGG ++TAAHC S+ + + TV Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + + V + H Y D++++ ++ + EL ++ A Sbjct: 61 MS-----SNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEAPIELAKADDAG--- 112 Query: 457 SPYLFQPNDTCIVSGWGREKDN-ERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 + P+ + GWG + ++ LQ V + S+ C + YG + M CAG Sbjct: 113 ----YAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYG-EYTPDAMVCAGV 167 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 +G +D C+GDSGGP+V NN + GV SWGE C +P PGVY +V Y+D + + Sbjct: 168 PEGGVDTCQGDSGGPMVV---NN--KLIGVTSWGEGCARPGKPGVYARVGAYYDVLMEQI 222 Query: 574 GRPFIS 579 +S Sbjct: 223 NAGAVS 228 >4BXW-A nrPDB Length = 423 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 74/252 (29%), Positives = 120/252 (47%), Gaps = 36/252 (14%) Query: 339 RIVGGKRAQLGDLPWQVAIKDA-SGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 RIV G +LG+ PWQ A+ D G+ CGG + ++LTAAHC+ ++T I V Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETET----ISVVVG 224 Query: 398 DWIHPDLKRIVIEYVDRIIFHE---------NYNAGTYQNDIALIEMKKDGNKKDCELPR 448 + ++ + VD+I H+ ++ Y DIA+I+MK + Sbjct: 225 EIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSE----N 280 Query: 449 SIPACVPWSPY---LFQPNDTCIVSGWGR------EKDNERVFSLQWGEVK--LISNCSK 497 +PAC+P + + + D IVSG+GR + +V + + + ++S+ + Sbjct: 281 VVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETP 340 Query: 498 FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPG 557 N F CAG DAC+GDSGGP + + ++ G+VS GE C + G Sbjct: 341 ITPNMF------CAGYDTLPRDACQGDSGGPHTTV-YRDTHFITGIVSSGEGCARNGKYG 393 Query: 558 VYTKVANYFDWI 569 YTK++ + WI Sbjct: 394 NYTKLSKFIPWI 405 >4WWY-A nrPDB Length = 224 Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 72/243 (29%), Positives = 108/243 (44%), Gaps = 40/243 (16%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS-----KTHRYQIWT 394 IVGG + +P+QV++ CGG I W+++A HC ++ H ++ Sbjct: 1 IVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKK----DGNKKDCELPRSI 450 +I+ +II H Y+ T NDI LI++ + + LP + Sbjct: 60 GNEQFIN----------AAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAP 109 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLISN--CSKFYGNRFYEK 506 PA C++SGWG + + LQ + ++S C Y + Sbjct: 110 PAT----------GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TS 158 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 566 M C G +G D+C+ DSGGP+VC + GVVSWG+ C + PGVYTKV NY Sbjct: 159 NMFCVGFLEGGKDSCQRDSGGPVVCNGQ-----LQGVVSWGDGCAQKNKPGVYTKVYNYV 213 Query: 567 DWI 569 WI Sbjct: 214 KWI 216 >1TON-A nrPDB Length = 235 Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 75/249 (30%), Positives = 115/249 (46%), Gaps = 41/249 (16%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + + PWQVA+ + CGG+ I W++TAAHC ++ YQ+ + Sbjct: 1 IVGGYKCEKNSQPWQVAVINE--YLCGGVLIDPSWVITAAHCY----SNNYQVLLGRNNL 54 Query: 400 I--HPDLKRIVI-------EYVDRIIFHENYN-AGTYQNDIALIEMKKD----GNKKDCE 445 P +R ++ +Y+ I+ ++ + ND+ L+ + + G K + Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 446 LPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGN 501 LP P TC+ SGWG +E V S LQ + L+SN C + Y + Sbjct: 115 LPTKEPKV----------GSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKD 164 Query: 502 RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYT 560 + M CAG +G D C GDSGGPL+C + G+ S G C KP+ P +Y Sbjct: 165 NVTDV-MLCAGEMEGGKDTCAGDSGGPLICDGV-----LQGITSGGATPCAKPKTPAIYA 218 Query: 561 KVANYFDWI 569 K+ + WI Sbjct: 219 KLIKFTSWI 227 >1PQ7-A nrPDB Length = 224 Score = 96.7 bits (239), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 106/241 (43%), Gaps = 32/241 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG A GD P+ V+I G CGG + +LTAAHC+ +QI Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG---- 56 Query: 400 IHPDLKRI---VIEYVDRIIFHENYNAGTYQNDIALIEMK----KDGNKKDCELPRSIPA 452 L R + + + H +Y+ ND+A++++ GN L S Sbjct: 57 ---SLSRTSGGITSSLSSVRVHPSYSG--NNNDLAILKLSTSIPSGGNIGYARLAASGSD 111 Query: 453 CVPWSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLIS--NCSKFYGNRFYEKEM 508 V S + V+GWG E + +L V ++S C YG +M Sbjct: 112 PVAGS--------SATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQM 163 Query: 509 ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDW 568 CAG G D+C+GDSGGP+V D++N + G VSWG C +P + GVY V + Sbjct: 164 FCAGVSSGGKDSCQGDSGGPIV--DSSNT--LIGAVSWGNGCARPNYSGVYASVGALRSF 219 Query: 569 I 569 I Sbjct: 220 I 220 >1GPZ-A nrPDB Length = 399 Score = 95.9 bits (237), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 78/248 (31%), Positives = 121/248 (48%), Gaps = 24/248 (9%) Query: 336 RRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +R++I+GG++A++G+ PWQV + G GG +G WILTAAH L K H Q + Sbjct: 154 QRQQIIGGQKAKMGNFPWQV-FTNIHG-RGGGALLGDRWILTAAHTL-YPKEHEAQSNAS 210 Query: 396 VVDWIH----PDLKRIVIEYVDRIIFHENY---NAGTYQNDIALIEMKKDGNKKDCELPR 448 + ++ +L ++ + R+ H +Y + ++ DIAL+E++ P Sbjct: 211 LDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLG----PN 266 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKD----NERVFSLQWGEVKLISNCSKFYGNRF- 503 +P C+P + + VSG+G ++ + R L + N + NR Sbjct: 267 LLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRG-KNRMD 325 Query: 504 -YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVW-GVVSWGENCGKPEFPGVYTK 561 + + M CAG DAC+GDSGG D N +V G+VSWG C + G YTK Sbjct: 326 VFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGY--GFYTK 383 Query: 562 VANYFDWI 569 V NY DWI Sbjct: 384 VLNYVDWI 391 >1MD7-A nrPDB Length = 328 Score = 95.9 bits (237), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 78/248 (31%), Positives = 121/248 (48%), Gaps = 24/248 (9%) Query: 336 RRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +R+RI+GG++A++G+ PWQV + G GG +G WILTAAH L K H Q + Sbjct: 86 QRQRIIGGQKAKMGNFPWQV-FTNIHG-RGGGALLGDRWILTAAHTL-YPKEHEAQSNAS 142 Query: 396 VVDWIH----PDLKRIVIEYVDRIIFHENY---NAGTYQNDIALIEMKKDGNKKDCELPR 448 + ++ +L ++ + R+ H +Y + ++ DIAL+E++ P Sbjct: 143 LDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLG----PN 198 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKD----NERVFSLQWGEVKLISNCSKFYGNRF- 503 +P C+P + + VSG+G ++ + R L + N + NR Sbjct: 199 LLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRG-KNRMD 257 Query: 504 -YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVW-GVVSWGENCGKPEFPGVYTK 561 + + M CAG DAC+GD+GG D N +V G+VSWG C + G YTK Sbjct: 258 VFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIGCSRGY--GFYTK 315 Query: 562 VANYFDWI 569 V NY DWI Sbjct: 316 VLNYVDWI 323 >1AO5-A nrPDB Length = 237 Score = 95.9 bits (237), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 69/245 (28%), Positives = 106/245 (43%), Gaps = 31/245 (12%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 +VGG + PWQVA+ CGG+ + W+LTAAHC +Y++W + Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY----VDQYEVWLG-KNK 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYN-----------AGTYQNDIALIEMKKDGNKKDCELPR 448 + + V + H +N + +D+ L+ + K + D P Sbjct: 56 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPI 115 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLIS--NCSKFYGNRFY 504 ++P P +P C+ SGWG ++ LQ + L+ NC+K Y + Sbjct: 116 ALPTKEP------KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT 169 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVAN 564 + M CAG G D C+ DSGGPL+C T +G V CGKP P +YT + Sbjct: 170 D-VMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVP----CGKPGVPAIYTNLIK 224 Query: 565 YFDWI 569 + WI Sbjct: 225 FNSWI 229 >2OLG-A nrPDB Length = 278 Score = 95.5 bits (236), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 89/292 (30%), Positives = 128/292 (43%), Gaps = 46/292 (15%) Query: 315 RRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAI--KDASGI---TCGGIY 369 R R LLP CG + +I+ G + PW I K++S CGG Sbjct: 3 RNRRPELLPN-DCG----YQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSL 57 Query: 370 IGGCWILTAAHCLR--------ASKTHRYQIWTTVVDWIHPD---------LKRIVIEYV 412 I +I+TAAHC+ A R W T D PD + + + Sbjct: 58 INNRYIVTAAHCVAGRVLRVVGALNKVRLGEWNTATD---PDCYGAVRVCVPDKPIDLGI 114 Query: 413 DRIIFHENYNAGTYQ--NDIALIEMKKDGNKKDCELPRSI-PACVPWSPYLFQPNDTCIV 469 + I H +Y G+ +DIALI + + E I P C+P Q V Sbjct: 115 EETIQHPDYVDGSKDRYHDIALIRLNRQ-----VEFTNYIRPVCLPQPNEEVQVGQRLTV 169 Query: 470 SGWGREKDNERVFSLQWGEVKLI--SNCSKFYGN---RFYEKEMECAGTYDGSIDACKGD 524 GWGR + + Q V ++ C+K +G R ++ CAG + + D+C GD Sbjct: 170 VGWGRTETGQYSTIKQKLAVPVVHAEQCAKTFGAAGVRVRSSQL-CAGG-EKAKDSCGGD 227 Query: 525 SGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRP 576 SGGPL+ AN ++ G+VS+G CG +PG+YTKV Y DWI ++ RP Sbjct: 228 SGGPLLAERANQQFFLEGLVSFGATCGTEGWPGIYTKVGKYRDWIEGNI-RP 278 >1SPJ-A nrPDB Length = 238 Score = 95.1 bits (235), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 108/251 (43%), Gaps = 42/251 (16%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + PWQ A+ S CGGI + W+LTAAHC+ + YQ+W + Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCI----SDNYQLWLGRHN- 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGT-----------YQNDIALIEMKKDGNK-----KD 443 + D +V H +N Y +D+ L+ + + + K Sbjct: 56 LFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKV 115 Query: 444 CELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLISN--CSKFY 499 ELP P + TC+ SGWG + F LQ ++K++ N C K + Sbjct: 116 VELPTEEP----------EVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAH 165 Query: 500 GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGV 558 + + M C G +G D C GDSGGPL+C + GV SWG CG P P V Sbjct: 166 VQKVTDF-MLCVGHLEGGKDTCVGDSGGPLMCDGV-----LQGVTSWGYVPCGTPNKPSV 219 Query: 559 YTKVANYFDWI 569 +V +Y WI Sbjct: 220 AVRVLSYVKWI 230 >1FDP-A nrPDB Length = 235 Score = 94.7 bits (234), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 112/240 (46%), Gaps = 21/240 (8%) Query: 337 RKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 R RI+GG+ A+ P+ +++ CGG+ + W+L+AAHCL + + Q+ Sbjct: 5 RGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGA 64 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 P+ + + + + R + H + T +D+ L+++ + P +PW Sbjct: 65 HSLSQPEPSKRLYDVL-RAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRP------LPW 117 Query: 457 SPY--LFQPNDTCIVSGWG-REKDNERVFSLQWGEVKLISNCS---KFYGNRFYEKEMEC 510 P C V+GWG R SLQ + ++ + + + + + + C Sbjct: 118 QRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMC 177 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 569 A + D+CKGDSGGPLVC + GVV+ G CG + PG+YT+VA+Y WI Sbjct: 178 AES--NRRDSCKGDSGGPLVCG-----GVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI 230 >1MZD-A nrPDB Length = 240 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 108/246 (43%), Gaps = 20/246 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHC-LRASKTHRYQIWTTVVD 398 I+GGK P+ +I+ CGG+ I W+LTAAHC R +K + Sbjct: 3 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 62 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + +E + + I + NDI L++++ +L + + S Sbjct: 63 LSKNEASKQTLE-IKKFIPFSRVTSDPQSNDIMLVKLQTA-----AKLNKHVKMLHIRSK 116 Query: 459 YLFQPNDTCIVSGWG-------REKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECA 511 + C V+GWG R D R ++ KL ++ S + G+ F K+M CA Sbjct: 117 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 176 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVA-NYFDWIS 570 G G D+CKGD+GGPL+C + +VS G CG PG+YT + Y WI Sbjct: 177 GDAKGQKDSCKGDAGGPLICKGVFHA-----IVSGGHECGVATKPGIYTLLTKKYQTWIK 231 Query: 571 YHVGRP 576 ++ P Sbjct: 232 SNLVPP 237 >3TK9-A nrPDB Length = 226 Score = 93.2 bits (230), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 72/243 (29%), Positives = 109/243 (44%), Gaps = 25/243 (10%) Query: 340 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG A+ P+ ++ + S CGGI + ++LTAAHC +S T Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSIN-----VTLG 55 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 I + V R I H YN + N+I L+++++ P +P+ Sbjct: 56 AHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPS---- 111 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCS---KFYGNRFYEKEME-CAG 512 S +P C V+GWG + +LQ + + +C F+GN Y + E C G Sbjct: 112 SKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGN--YSRATEICVG 169 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYH 572 + KGDSGGPLVC D G++S+G G P PGVY KV+++ WI Sbjct: 170 DPKKTQTGFKGDSGGPLVCKDVAQ-----GILSYGNKKGTP--PGVYIKVSHFLPWIKRT 222 Query: 573 VGR 575 + R Sbjct: 223 MKR 225 >1M9U-A nrPDB Length = 241 Score = 92.8 bits (229), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 113/254 (44%), Gaps = 41/254 (16%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGI---TCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 ++GG A G+ PWQ++ + SG +CG + L+A+HC+ + ++ + Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGT--YQNDIALIEMKKD----GNKKDCELPRSI 450 W D VD HENY AGT Y NDIA++ + GN + LP + Sbjct: 61 --WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPAN- 117 Query: 451 PACVPWSPYLFQPND----TCIVSGWGR-EKDNERVFSLQWGEVKLISNCS------KFY 499 ND TC++SGWGR + N LQ + +I+ Sbjct: 118 -----------NNNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVG 166 Query: 500 GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCG----KPEF 555 G ++ + C G+ AC GDSGGPL C D T V GV SW + G P++ Sbjct: 167 GANIWDNHI-CVQDPAGNTGACNGDSGGPLNCPDGG--TRVVGVTSWVVSSGLGACLPDY 223 Query: 556 PGVYTKVANYFDWI 569 P VYT+V+ Y WI Sbjct: 224 PSVYTRVSAYLGWI 237 >1FI8-A nrPDB Length = 228 Score = 91.7 bits (226), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 70/238 (29%), Positives = 108/238 (45%), Gaps = 25/238 (10%) Query: 340 IVGGKRAQLGDLPW----QVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+GG A+ P+ Q+ + + CGG I ++LTAAHC + Q+ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHC----SGSKIQVTLG 56 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + + + +I V +II H YN+ T NDI L+++K + P ++P Sbjct: 57 AHNIKEQEKMQQIIPVV-KIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPR--- 112 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI----SNCSKFYGNRFYEKEMECA 511 +P D C V+GWG+ + +S EV+L C + N F + CA Sbjct: 113 -RNVKVKPGDVCYVAGWGKLGPMGK-YSDTLQEVELTVQEDQKCESYLKNYFDKANEICA 170 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G + +GDSGGPLVC G+VS+G+N G P +TKV+ + WI Sbjct: 171 GDPKIKRASFRGDSGGPLVCKKV-----AAGIVSYGQNDG--STPRAFTKVSTFLSWI 221 >2QY0-B nrPDB Length = 242 Score = 91.3 bits (225), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 77/244 (31%), Positives = 117/244 (47%), Gaps = 24/244 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG++A++G+ PWQV + G GG +G WILTAAH L K H Q ++ + Sbjct: 1 IIGGQKAKMGNFPWQV-FTNIHG-RGGGALLGDRWILTAAHTLYP-KEHEAQSNASLDVF 57 Query: 400 IH----PDLKRIVIEYVDRIIFHENY---NAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 + +L ++ + R+ H +Y + ++ DIAL+E++ P +P Sbjct: 58 LGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLG----PNLLPI 113 Query: 453 CVPWSPYLFQPNDTCIVSGWGREKD----NERVFSLQWGEVKLISNCSKFYGNRF--YEK 506 C+P + + VSG+G ++ + R L + N + NR + + Sbjct: 114 CLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGK-NRMDVFSQ 172 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVW-GVVSWGENCGKPEFPGVYTKVANY 565 M CAG DAC+GDSGG D N +V G+VSWG C + G YTKV NY Sbjct: 173 NMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGY--GFYTKVLNY 230 Query: 566 FDWI 569 DWI Sbjct: 231 VDWI 234 >2PSX-A nrPDB Length = 227 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 69/236 (29%), Positives = 113/236 (47%), Gaps = 23/236 (9%) Query: 340 IVGGKRAQLGDLPWQVAIK-DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 I+ G + PWQ A+ + + CG + + W+LTAAHC + K R ++ + Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK--KVFRVRLGHYSLS 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 ++ +++ + I H Y+ + ND+ LI++ + P ++ + P + Sbjct: 59 PVYESGQQMFQGV--KSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA- 115 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 C+VSGWG K + F LQ + ++S C Y R + M CAG Sbjct: 116 -----GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY-PRQIDDTMFCAGDK 169 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWI 569 G D+C+GDSGGP+VC + + G+VSWG+ C +P PGVYT + + WI Sbjct: 170 AGR-DSCQGDSGGPVVCNGS-----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 219 >1ELT-A nrPDB Length = 236 Score = 90.5 bits (223), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 72/246 (29%), Positives = 119/246 (48%), Gaps = 28/246 (11%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGI----TCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG+ AQ PWQ++++ SG TCGG I W++TAAHC+ +++T R + Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYN----AGTYQNDIALIEMKKDGNKKDCELPRSIP 451 ++ + + I V+ + H +N AG Y DIAL+ + + ++P Sbjct: 61 NLN---TNEGKEQIMTVNSVFIHSGWNSDDVAGGY--DIALLRLNTQASLNSAVQLAALP 115 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLISNC----SKFYGNRFYEK 506 S + N+ C ++GWG+ + SL+ + + + S ++G+ + Sbjct: 116 P----SNQILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTV-KT 170 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSW--GENCGKPEFPGVYTKVAN 564 M CAG G+ C GDSGGPL C N YV GV S+ C + P V+T+V+ Sbjct: 171 TMVCAG--GGANSGCNGDSGGPLNC-QVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSA 227 Query: 565 YFDWIS 570 Y W++ Sbjct: 228 YISWMN 233 >3I77-A nrPDB Length = 230 Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 113/238 (47%), Gaps = 21/238 (8%) Query: 340 IVGGKRAQLGDLPWQV-AIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT-VV 397 +VGG RA G+ P+ V I + + CGG +LTAAHC+ S + T VV Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 D ++ +++ + TY D ALI++ + N+ ++ + Sbjct: 61 DLQSSSAVKV---RSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTA------ 111 Query: 458 PYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISNCSKFYGNRF--YEKEMECAGT 513 T V+GWG RE +++ + L+ V +S+ + + F EM CAG Sbjct: 112 ----YNQGTFTVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSSSSFILVANEMICAGY 166 Query: 514 YD-GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 D G +D C+GDSGGP+ D + G+VSWG C +P +PGVYT+V+ + I+ Sbjct: 167 PDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIA 224 >1YM0-A nrPDB Length = 238 Score = 90.1 bits (222), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 70/239 (29%), Positives = 112/239 (46%), Gaps = 15/239 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGIT--CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 IVGG A+ + PWQV+++ S + CGG I W++ AAHC++ + Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 D R + VD I +ENY+ T +ND+++I+ P P P + Sbjct: 61 DSSAASTVRQTHD-VDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPD--PAN 117 Query: 458 PYLFQPNDTCIVSGWGREKDNER--VFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 Y+++ + SGWG L++ + + +N C Y + +M CA Sbjct: 118 DYVYRKSQ---CSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATD 174 Query: 514 YDGSID--ACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 G D +C+GDSGGPL D + + + G+VSWG C +PGVY++V + WI+ Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCAS-GYPGVYSRVGFHAGWIT 232 >5LPF-A nrPDB Length = 234 Score = 89.0 bits (219), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 69/235 (29%), Positives = 104/235 (44%), Gaps = 32/235 (13%) Query: 349 GDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIV 408 G PWQV++ + C G+ + W+LTAAHC +W V D L+ Sbjct: 13 GSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC------GNKPLWARVGDDHLLLLQGEQ 66 Query: 409 IEYVDRIIFHENYNAG--------TYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYL 460 + R + H Y+ G T ++D+ L+++ + PR +P+ Sbjct: 67 LRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLA----RPVVLGPRVRALQLPYR--C 120 Query: 461 FQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYDG 516 QP D C V+GWG ++ L + ++S C FY M CAG G Sbjct: 121 AQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPG-VVTNNMICAGLDRG 179 Query: 517 SIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWIS 570 D C+ DSGGPLVC + + G++SWG CG + P VYT++ Y WI+ Sbjct: 180 Q-DPCQSDSGGPLVCDET-----LQGILSWGVYPCGSAQHPAVYTQICKYMSWIN 228 >2FMJ-A nrPDB Length = 222 Score = 88.6 bits (218), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 72/236 (30%), Positives = 111/236 (47%), Gaps = 25/236 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT-VVD 398 +VGG RA G+ P+ V + + CGG +LTAAHC+ S + T VVD Sbjct: 1 VVGGTRAAQGEFPFMVRLS----MGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 ++ +++ YN GT + D ALI++ + N+ ++ + Sbjct: 57 LQSSSAVKV---RSTKVLQAPGYN-GTGK-DWALIKLAQPINQPTLKIATTTA------- 104 Query: 459 YLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 T V+GWG RE +++ + L+ V +S+ C YGN E CAG Sbjct: 105 ---YNQGTFTVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSAYGNELVANEEICAGYD 160 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 G +D C+GDSGGP+ D + G+VSWGE C + GVYT+V+ + I+ Sbjct: 161 TGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIA 216 >1KYN-A nrPDB Length = 235 Score = 88.2 bits (217), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/238 (28%), Positives = 116/238 (48%), Gaps = 28/238 (11%) Query: 340 IVGGKRAQLGDLPWQ--VAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG+ ++ P+ + I+ +G + CGG + ++LTAAHC ++ V Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSN--------INV 52 Query: 397 VDWIHPDLKRIVIEY---VDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPAC 453 H +R + R I H YN T QNDI L+++ + + P ++P Sbjct: 53 TLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRA 112 Query: 454 VPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECA 511 +P C V+GWGR +L+ ++++ + C + +G+ + + C Sbjct: 113 QEG----LRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGS-YDPRRQICV 167 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G A KGDSGGPL+C NNV + G+VS+G++ G P P V+T+V+++ WI Sbjct: 168 GDRRERKAAFKGDSGGPLLC---NNVAH--GIVSYGKSSGVP--PEVFTRVSSFLPWI 218 >2XXL-A nrPDB Length = 408 Score = 87.8 bits (216), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 77/260 (29%), Positives = 114/260 (43%), Gaps = 34/260 (13%) Query: 338 KRIVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQI- 392 +R+ G +L PW ++ S CGG I +ILTAAHC+ + Y+I Sbjct: 117 QRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIR 176 Query: 393 -----WTTVVDWIHPDLKR-----IVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKK 442 +T D K+ +V +++ + HE Y+A +DIAL+++ + Sbjct: 177 LGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKL-----NR 231 Query: 443 DCELPRSI-PACVPWSPYLFQPND---TCIVSGWGREKDNERVFSLQWGEVKLI--SNCS 496 + I P C+P + L + + T V+GWG ++ L V L S CS Sbjct: 232 SVPFQKHIKPICLPITDELKEKAEQISTYFVTGWGTTENGSSSDVLLQANVPLQPRSACS 291 Query: 497 KFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYV-----WGVVSWG-ENC 550 + Y R C G D D+CKGDSGGPL Y +G+VS G C Sbjct: 292 QAY-RRAVPLSQLCVGGGDLQ-DSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTC 349 Query: 551 GKPEFPGVYTKVANYFDWIS 570 G+ PG+YT V Y WI+ Sbjct: 350 GQISLPGLYTNVGEYVQWIT 369 >1MKW-K nrPDB Length = 308 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 88/269 (32%), Positives = 116/269 (43%), Gaps = 44/269 (16%) Query: 339 RIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWT-- 394 RIV G+ A++G PWQV + K + CG I W+LTAAHCL Y W Sbjct: 49 RIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLL------YPPWDKN 102 Query: 395 -TVVDWI---------HPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKD 443 TV D + + K I +D+I H YN DIAL+++K+ Sbjct: 103 FTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRP----- 157 Query: 444 CELPRSI-PACVP---WSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLIS---- 493 EL I P C+P + L V+GWG RE V +Q +++++ Sbjct: 158 IELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLV 217 Query: 494 ---NCSKFYGNRFYEKEMECAGTYDGSI---DACKGDSGGPLVCMDA-NNVTYVWGVVSW 546 C R + M CAG G DAC+GDSGGP V NN Y G+VSW Sbjct: 218 ERPVCKASTRIRITDN-MFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSW 276 Query: 547 GENCGKPEFPGVYTKVANYFDWISYHVGR 575 GE C + G YT V WI + R Sbjct: 277 GEGCDRDGKYGFYTHVFRLKKWIQKVIDR 305 >2HLC-A nrPDB Length = 230 Score = 85.5 bits (210), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 70/243 (28%), Positives = 108/243 (44%), Gaps = 18/243 (7%) Query: 340 IVGGKRAQLGDLPWQ----VAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+ G A G P+Q + ++D + CGG I WILTAAHC+ + + + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 V + + +RII H +N TY ND+ALI++ + + P +P+ Sbjct: 61 V------QYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPHVEYTDNIQ-PIRLPSGEE 113 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYD 515 + N VSGWG+ + + + V C++ Y + C T D Sbjct: 114 LNNKF--ENIWATVSGWGQSNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSD 171 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCG-KPEFPGVYTKVANYFDWISYHVG 574 G C GDSGGP V D N + GVVS+ G + P +++V +Y DWI + G Sbjct: 172 GK-SPCFGDSGGPFVLSDKN---LLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQNTG 227 Query: 575 RPF 577 F Sbjct: 228 IKF 230 >1EUF-A nrPDB Length = 227 Score = 85.1 bits (209), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 72/236 (30%), Positives = 111/236 (47%), Gaps = 23/236 (9%) Query: 340 IVGGKRAQLGDLPWQVAI---KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG A+ P+ + CGG + ++LTAAHCL +S + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSS----INVTLGA 56 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + + + + VI V R I H +YN T NDI L+++ + + D + P +P Sbjct: 57 HNIMERERTQQVIP-VRRPIPHPDYNDETLANDIMLLKLTRKADITD----KVSPINLPR 111 Query: 457 SPYLFQPNDTCIVSGWGREKDN-ERVFSLQWGEVKLIS--NCSKFYGNRFYEKEMECAGT 513 S +P C V+GWGR N LQ ++++ S C + N ++ CAG Sbjct: 112 SLAEVKPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQI-CAGD 170 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 ++ GDSGGPLVC N V G+VS+G N G P VYT+++++ WI Sbjct: 171 PSKRKNSFSGDSGGPLVC---NGV--AQGIVSYGRNDGT--TPDVYTRISSFLSWI 219 >2EEK-A nrPDB Length = 220 Score = 84.7 bits (208), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 69/238 (28%), Positives = 105/238 (44%), Gaps = 31/238 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG QV++ CGG + W+++AAHC ++ + + Sbjct: 1 IVGGYECTKHSQAHQVSLNSGYHF-CGGSLVSKDWVVSAAHCYKS-------VLRVRLGE 52 Query: 400 IHPDLKRIVIEYVDR--IIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 H + +Y+ +I H NY++ NDI LI++ K ++P Sbjct: 53 HHIRVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAAD 112 Query: 458 PYLFQPNDTCIVSGWGR------EKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECA 511 + C VSGWG + D + SL + ++C+ Y + M CA Sbjct: 113 ATM------CTVSGWGNTMSSVADGDKLQCLSL---PILSHADCANSYPGMI-TQSMFCA 162 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G +G D+C+GDSGGP+VC N V + GVVSWG C + + PGVY KV W+ Sbjct: 163 GYLEGGKDSCQGDSGGPVVC---NGV--LQGVVSWGYGCAERDHPGVYAKVCVLSGWV 215 >4LK4-A nrPDB Length = 357 Score = 84.7 bits (208), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/269 (27%), Positives = 113/269 (42%), Gaps = 61/269 (22%) Query: 338 KRIVGGKRAQLGDLPWQVAI----KDA-SGITCGGIYIGGCWILTAAHCLRASKTHRYQI 392 RI+ G A + P VA+ DA G CGG ++GG ++LTAAHC + + Sbjct: 9 SRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVDV 68 Query: 393 WTTVVDWIHPDL-KRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELP---- 447 D + +RI + + R H +Y+ NDIA++E+ + + L Sbjct: 69 IIGAYDLNNSSQGERIAAQKIYR---HLSYSPSNLLNDIAIVELAQTSSLPAITLAGPAT 125 Query: 448 -RSIPACVPWSPYLFQPNDTCIVSGWG---REKDNERVFSLQWGEVKLIS---------- 493 S+PA P + V+GWG + K + LQ +V L+S Sbjct: 126 RTSLPALTPLT-----------VAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQH 174 Query: 494 ------NCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG 547 N + F R + D+C+GD+GGP+V G+VSWG Sbjct: 175 GISSDPNSTNFCAARLTK-------------DSCQGDAGGPIVVKTGRE---QLGIVSWG 218 Query: 548 -ENCGKPEFPGVYTKVANYFDWISYHVGR 575 E C K GVYT V+ + DWI+ H + Sbjct: 219 DEQCAKTGTYGVYTNVSYFRDWITKHTNQ 247 >1ETT-H nrPDB Length = 259 Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 88/268 (32%), Positives = 116/268 (43%), Gaps = 44/268 (16%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWT--- 394 IV G+ A++G PWQV + K + CG I W+LTAAHCL Y W Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLL------YPPWDKNF 54 Query: 395 TVVDWI-------HPDLKRIV--IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDC 444 TV D + +R V I +D+I H YN DIAL+++K+ Sbjct: 55 TVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRP-----I 109 Query: 445 ELPRSI-PACVP---WSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLIS----- 493 EL I P C+P + L V+GWG RE V +Q +++++ Sbjct: 110 ELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVE 169 Query: 494 --NCSKFYGNRFYEKEMECAGTYDGSI---DACKGDSGGPLVCMDA-NNVTYVWGVVSWG 547 C R + M CAG G DAC+GDSGGP V NN Y G+VSWG Sbjct: 170 RPVCKASTRIRITD-NMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWG 228 Query: 548 ENCGKPEFPGVYTKVANYFDWISYHVGR 575 E C + G YT V WI + R Sbjct: 229 EGCDRDGKYGFYTHVFRLKKWIQKVIDR 256 >5FCR-A nrPDB Length = 234 Score = 82.8 bits (203), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 64/236 (27%), Positives = 107/236 (45%), Gaps = 18/236 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTTVVD 398 I+GG+ A P+ +++ CGG + W+L+AAHC+ + Q+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 P+ + + V ++ H + ++D+ L ++ ++ + P P + + Sbjct: 61 LSAPEPYKRWYD-VQSVVPHPGSRPDSLEDDLILFKLSQNASLG----PHVRPLPLQYED 115 Query: 459 YLFQPNDTCIVSGWGR-EKDNERVFSLQWGEVKLISNCS---KFYGNRFYEKEMECAGTY 514 +P C V+GWG R L V +++ + + Y + M CA + Sbjct: 116 KEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAES- 174 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 569 D C+GDSG PLVC DA V GVV+WG CG + PGVYT+V++Y WI Sbjct: 175 -NRRDTCRGDSGSPLVCGDA-----VEGVVTWGSRVCGNGKKPGVYTRVSSYRMWI 224 >1IAU-A nrPDB Length = 227 Score = 82.8 bits (203), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 74/245 (30%), Positives = 114/245 (46%), Gaps = 28/245 (11%) Query: 340 IVGGKRAQLGDLPWQ--VAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG A+ P+ + I D + CGG I ++LTAAHC +S + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSIN--VTLGAHN 58 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + P + I ++ R I H YN + NDI L+++++ + P +P+ Sbjct: 59 IKEQEPTQQFIPVK---RPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS---- 111 Query: 457 SPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLI----SNCSKFYGNRFYEKEME-C 510 + +P TC V+GWG+ + +LQ EVK+ C +Y+ +E C Sbjct: 112 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQ--EVKMTVQEDRKCESDL-RHYYDSTIELC 168 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 G + + KGDSGGPLVC N V G+VS+G N G P P TKV+++ WI Sbjct: 169 VGDPEIKKTSFKGDSGGPLVC---NKVAQ--GIVSYGRNNGMP--PRACTKVSSFVHWIK 221 Query: 571 YHVGR 575 + R Sbjct: 222 KTMKR 226 >2ZKS-A nrPDB Length = 240 Score = 82.8 bits (203), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 69/244 (28%), Positives = 104/244 (42%), Gaps = 22/244 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG+ P+ +++ CGG+ + W+LTAAHCL A + + ++ + Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL-AQRMAQLRLVLGLHTL 59 Query: 400 IHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 P L ++ I H Y +ND+AL+++ DG K R P +P Sbjct: 60 DSPGLT----FHIKAAIQHPRYKPVPALENDLALLQL--DGKVKPSRTIR--PLALPSKR 111 Query: 459 YLFQPNDTCIVSGWGREKDNERV------FSLQWGEVKLISNCSKFYGNRFYEKEMECAG 512 + C ++GWG R+ LQ + ++ +N S+F+ N M C Sbjct: 112 QVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNN-SRFW-NGSLSPSMVCLA 169 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEF-PGVYTKVANYFDWISY 571 CKGDSGGPLVC + GV+S+ F P V T VA Y WI Sbjct: 170 ADSKDQAPCKGDSGGPLVCGKGRVLA---GVLSFSSRVCTDIFKPPVATAVAPYVSWIRK 226 Query: 572 HVGR 575 GR Sbjct: 227 VTGR 230 >2V35-A nrPDB Length = 240 Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 75/249 (30%), Positives = 116/249 (46%), Gaps = 33/249 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGI----TCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG AQ P Q++++ SG TCGG I W++TAAHC+ T R Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFR-----V 55 Query: 396 VVDWIHPDLKRIVIEY--VDRIIFHENYN----AGTYQNDIALIEMKKDGNKKD-CELPR 448 VV + + +Y V +I+ H +N A Y DIAL+ + + +L Sbjct: 56 VVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGY--DIALLRLAQSVTLNSYVQL-- 111 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLIS----NCSKFYGNRF 503 +P + + N C ++GWG + N ++ +LQ + + + S ++G+ Sbjct: 112 ---GVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTV 168 Query: 504 YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE--NCGKPEFPGVYTK 561 + M CAG DG C+GDSGGPL C+ N V GV S+ C P V+T+ Sbjct: 169 -KNSMVCAGG-DGVRSGCQGDSGGPLHCL-VNGQYAVHGVTSFVSRLGCNVTRKPTVFTR 225 Query: 562 VANYFDWIS 570 V+ Y WI+ Sbjct: 226 VSAYISWIN 234 >3BEU-A nrPDB Length = 224 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 67/236 (28%), Positives = 107/236 (45%), Gaps = 23/236 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT-VVD 398 +VGG RA G+ P+ V + + CGG +LTAAHC+ S + T VVD Sbjct: 1 VVGGTRAAQGEFPFMVRLS----MGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 ++ +++ + TY D ALI++ + N+ ++ + Sbjct: 57 LQSSSAVKV---RSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTA------- 106 Query: 459 YLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISNCSKFYGNRF--YEKEMECAGTY 514 T V+GWG RE +++ + L+ V +S+ + + F EM CAG Sbjct: 107 ---YNQGTFTVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSSSSFILVANEMICAGYD 162 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 D C+GDSGGP+ D + G+VSWGE C + GVYT+V+ + I+ Sbjct: 163 TKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIA 218 >2ASU-B nrPDB Length = 234 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/239 (27%), Positives = 106/239 (44%), Gaps = 27/239 (11%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRA--SKTHRYQIW--T 394 +VGG G+ PW V++++ G CGG + WILTA C + Y++W T Sbjct: 1 VVGG---HPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 395 TVVDWIH--PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 + H P L+R+ + + G + + L+++++ R Sbjct: 58 LFQNPQHGEPSLQRVPVAKMV---------CGPSGSQLVLLKLERSVTLNQ----RVALI 104 Query: 453 CVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMEC 510 C+P Y+ P C ++GWG K L + +ISN C+ + R E EM C Sbjct: 105 CLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEM-C 163 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 + AC+GD GGPL C N+ G++ C + +P V+T+V+ + DWI Sbjct: 164 TEGLLAPVGACEGDYGGPLACFTHNSWVLE-GIIIPNRVCARSRWPAVFTRVSVFVDWI 221 >4NZQ-A nrPDB Length = 557 Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 82/267 (30%), Positives = 110/267 (41%), Gaps = 52/267 (19%) Query: 339 RIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 RIV G A++G PWQV + K + CG I W+LTAAHCL Y W Sbjct: 298 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL------LYPPWDK- 350 Query: 397 VDWIHPDL------------KRIV--IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNK 441 ++ DL +R + I +++I H YN DIAL+++KK Sbjct: 351 -NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAF 409 Query: 442 KDCELPRSIPACVP---WSPYLFQPNDTCIVSGWGREKDN------------ERVFSLQW 486 D P C+P + L Q V+GWG K+ +V +L Sbjct: 410 SD----YIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPI 465 Query: 487 GEVKLISNCSKFYGNRFYEKEMECAGTYDGS---IDACKGDSGGPLVCMDA-NNVTYVWG 542 E + + ++ M CAG DAC+GDSGGP V NN Y G Sbjct: 466 VERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMG 521 Query: 543 VVSWGENCGKPEFPGVYTKVANYFDWI 569 +VSWGE C + G YT V WI Sbjct: 522 IVSWGEGCDRDGKYGFYTHVFRLKKWI 548 >3NXP-A nrPDB Length = 424 Score = 78.6 bits (192), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 82/267 (30%), Positives = 110/267 (41%), Gaps = 52/267 (19%) Query: 339 RIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 RIV G A++G PWQV + K + CG I W+LTAAHCL Y W Sbjct: 165 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL------LYPPWDK- 217 Query: 397 VDWIHPDL------------KRIV--IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNK 441 ++ DL +R + I +++I H YN DIAL+++KK Sbjct: 218 -NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAF 276 Query: 442 KDCELPRSIPACVP---WSPYLFQPNDTCIVSGWGREKDN------------ERVFSLQW 486 D P C+P + L Q V+GWG K+ +V +L Sbjct: 277 SDY----IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPI 332 Query: 487 GEVKLISNCSKFYGNRFYEKEMECAGTYDGS---IDACKGDSGGPLVCMDA-NNVTYVWG 542 E + + ++ M CAG DAC+GDSGGP V NN Y G Sbjct: 333 VERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMG 388 Query: 543 VVSWGENCGKPEFPGVYTKVANYFDWI 569 +VSWGE C + G YT V WI Sbjct: 389 IVSWGEGCDRDGKYGFYTHVFRLKKWI 415 >4X0L-C nrPDB Length = 259 Score = 78.6 bits (192), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 71/256 (27%), Positives = 113/256 (44%), Gaps = 40/256 (15%) Query: 338 KRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 +RI+GG G PWQ + +T G I W+LT A L + + T Sbjct: 13 QRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSEN----ATAK 68 Query: 398 DWIHPDL-----KRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 D I P L K+ ++E +++++ H NY+ Q DI LI++K+ + + R +P Sbjct: 69 D-IAPTLTLYVGKKQLVE-IEKVVLHPNYS----QVDIGLIKLKQKVSVNE----RVMPI 118 Query: 453 CVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI--SNCSKFY-GNRFYEKEME 509 C+P Y + VSGWGR + + L++ + + C + Y G+ EK+ Sbjct: 119 CLPSKDYA-EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTP 177 Query: 510 ---------------CAGTYDGSIDACKGDSGGPLVCMDANNVT-YVWGVVSWGENCGKP 553 CAG D C GD+G D T Y G++S+ ++C Sbjct: 178 KSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVA 237 Query: 554 EFPGVYTKVANYFDWI 569 E+ GVY KV + DW+ Sbjct: 238 EY-GVYVKVTSIQDWV 252 >4WJG-C nrPDB Length = 315 Score = 78.6 bits (192), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 71/256 (27%), Positives = 113/256 (44%), Gaps = 40/256 (15%) Query: 338 KRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 +RI+GG G PWQ + +T G I W+LT A L + + T Sbjct: 69 QRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSEN----ATAK 124 Query: 398 DWIHPDL-----KRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 D I P L K+ ++E +++++ H NY+ Q DI LI++K+ + + R +P Sbjct: 125 D-IAPTLTLYVGKKQLVE-IEKVVLHPNYS----QVDIGLIKLKQKVSVNE----RVMPI 174 Query: 453 CVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI--SNCSKFY-GNRFYEKEME 509 C+P Y + VSGWGR + + L++ + + C + Y G+ EK+ Sbjct: 175 CLPSKDYA-EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTP 233 Query: 510 ---------------CAGTYDGSIDACKGDSGGPLVCMDANNVT-YVWGVVSWGENCGKP 553 CAG D C GD+G D T Y G++S+ ++C Sbjct: 234 KSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVA 293 Query: 554 EFPGVYTKVANYFDWI 569 E+ GVY KV + DW+ Sbjct: 294 EY-GVYVKVTSIQDWV 308 >3RP2-A nrPDB Length = 224 Score = 78.2 bits (191), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 68/243 (27%), Positives = 113/243 (46%), Gaps = 35/243 (14%) Query: 340 IVGGKRAQLGDLPWQ----VAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+GG + P+ + + + CGG I ++LTAAHC T Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGRE--------IT 52 Query: 396 VVDWIHPDLKRIVIEY---VDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 V+ H KR + V++ I HE+YN+ +DI L+++ +K EL ++ Sbjct: 53 VILGAHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKL-----EKKVELTPAVNV 107 Query: 453 CVPWSPYLF-QPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN--CSKFYGNRFYEKEM 508 SP F P C +GWG+ + ++L+ E++++ C + R+YE + Sbjct: 108 VPLPSPSDFIHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDY---RYYEYKF 164 Query: 509 E-CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFD 567 + C G+ A GDSGGPL+C + G+VS+G KP P ++T+V+ Y Sbjct: 165 QVCVGSPTTLRAAFMGDSGGPLLCAGVAH-----GIVSYGHPDAKP--PAIFTRVSTYVP 217 Query: 568 WIS 570 WI+ Sbjct: 218 WIN 220 >3G01-A nrPDB Length = 227 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 63/210 (30%), Positives = 92/210 (43%), Gaps = 23/210 (10%) Query: 365 CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAG 424 CGG + ++LTAAHC S T T I + I V + I H +YN Sbjct: 30 CGGFLVRDKFVLTAAHCKGRSMT-----VTLGAHNIKAKEETQQIIPVAKAIPHPDYNPD 84 Query: 425 TYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGR-EKDNERVFS 483 NDI L+++ ++ + P ++P +P D C V+GWG+ D E F Sbjct: 85 DRSNDIMLLKLVRNAKRTRAVRPLNLPR----RNAHVKPGDECYVAGWGKVTPDGE--FP 138 Query: 484 LQWGEVKLISN----CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTY 539 EVKL C + + + C G + +GDSGGPLVC A Sbjct: 139 KTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGASFRGDSGGPLVCKRA----- 193 Query: 540 VWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G+VS+G+ G P V+T+V ++ WI Sbjct: 194 AAGIVSYGQTDG--SAPQVFTRVLSFVSWI 221 >3K65-B nrPDB Length = 308 Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 80/267 (29%), Positives = 108/267 (40%), Gaps = 52/267 (19%) Query: 339 RIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 RIV G A++G PWQV + K + CG I W+LTAAHCL Y W Sbjct: 49 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL------LYPPWDK- 101 Query: 397 VDWIHPDLKRIV--------------IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNK 441 ++ DL + I +++I H YN DIAL+++KK Sbjct: 102 -NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAF 160 Query: 442 KDCELPRSIPACVP---WSPYLFQPNDTCIVSGWGREKDN------------ERVFSLQW 486 D P C+P + L Q V+GWG K+ +V +L Sbjct: 161 SDY----IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPI 216 Query: 487 GEVKLISNCSKFYGNRFYEKEMECAGTYDGS---IDACKGDSGGPLVCMDA-NNVTYVWG 542 E + + ++ M CAG DAC+GD+GGP V NN Y G Sbjct: 217 VERPVCKDSTRIR----ITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMG 272 Query: 543 VVSWGENCGKPEFPGVYTKVANYFDWI 569 +VSWGE C + G YT V WI Sbjct: 273 IVSWGEGCDRDGKYGFYTHVFRLKKWI 299 >2AIQ-A nrPDB Length = 231 Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 67/236 (28%), Positives = 101/236 (42%), Gaps = 25/236 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + + +A+ A+G CGG I W+LTA HC R + R + + Sbjct: 1 VIGGDECNINEHRF-LALVYANGSLCGGTLINQEWVLTARHCDRGNM--RIYLGMHNLKV 57 Query: 400 IHPD-LKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 ++ D L+R E + N + DI LI + + P S+P+ P Sbjct: 58 LNKDALRRFPKE---KYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPP--- 111 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLI--SNCSKFYGNRFYEKEMECAGTY 514 C + GWG + ++ + C Y + CAG Sbjct: 112 ---SVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAY--KGLAATTLCAGIL 166 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 569 +G D CKGDSGGPL+C G++S G N C +P PG+YTKV +Y DWI Sbjct: 167 EGGKDTCKGDSGGPLICNGQ-----FQGILSVGGNPCAQPRKPGIYTKVFDYTDWI 217 >4F4O-C nrPDB Length = 347 Score = 77.4 bits (189), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 72/267 (26%), Positives = 114/267 (42%), Gaps = 40/267 (14%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK 386 CG + +RI+GG G PWQ + +T G I W+LT A LR Sbjct: 90 CGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGH 149 Query: 387 THRYQIWTTVVDWIHPDLKRIV-----IEYVDRIIFHENYNAGTYQNDIALIEMKKDGNK 441 + T I P L+ V +E ++++IFH + + DI LI++K+ Sbjct: 150 KN-----DTKAKDIAPTLRLYVGKKQEVE-IEKVIFHPDNST----VDIGLIKLKQKVPV 199 Query: 442 KDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI--SNCSKFY 499 + R +P C+P Y+ VSGWGR + L++ + + C ++Y Sbjct: 200 NE----RVMPICLPSKDYV-NVGLVGYVSGWGRNANLNFTEHLKYVMLPVADQEKCVQYY 254 Query: 500 -GNRFYEKEME---------------CAGTYDGSIDACKGDSGGPLVCMDANNVT-YVWG 542 G+ EK+ CAG D C GD+G D ++ T Y G Sbjct: 255 EGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAG 314 Query: 543 VVSWGENCGKPEFPGVYTKVANYFDWI 569 ++S+ ++C E+ GVY +V + DWI Sbjct: 315 ILSFDKSCRTAEY-GVYVRVTSILDWI 340 >1AZZ-A nrPDB Length = 226 Score = 76.3 bits (186), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 104/244 (42%), Gaps = 30/244 (12%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG A P Q A+ CGG I WILTAAHC+ + + VV Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAG------FVDVVLG 54 Query: 400 IH----PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 H + ++ I+ D + HENYN+ NDIA+I + +P+ Sbjct: 55 AHNIREDEATQVTIQSTDFTV-HENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDV 113 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECA 511 + P +GWG D+ S L+ +V ++SN C YG C Sbjct: 114 GVGTVVTP------TGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG--IVTDGNICI 165 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCG-KPEFPGVYTKVANYFDWIS 570 + G C GDSGGPL + N +TY G+ S+G G + +P +T+V + DWI Sbjct: 166 DSTGGK-GTCNGDSGGPL---NYNGLTY--GITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 Query: 571 YHVG 574 G Sbjct: 220 TQTG 223 >1OP0-A nrPDB Length = 234 Score = 76.3 bits (186), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 66/240 (27%), Positives = 99/240 (41%), Gaps = 22/240 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + + VA + +G CGG I W++TAAHC S + Q+ Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHC--DSTDFQMQLGVHSKKV 58 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD-GNKKDCELPRSIPACVPWSP 458 ++ D + ++ I N DI LI++ K N K A + Sbjct: 59 LNEDEQ--TRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHI-------APLSLPS 109 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 C + GWG + F + L+ + C Y E CAG Sbjct: 110 SPPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIV 169 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHV 573 G D C GDSGGPL+C G+VS+G + CG+ PG+YT V +Y DWI ++ Sbjct: 170 QGGKDTCGGDSGGPLICNGQ-----FQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >1GVZ-A nrPDB Length = 237 Score = 75.5 bits (184), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 69/245 (28%), Positives = 99/245 (40%), Gaps = 31/245 (12%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG + PWQVA+ CGG+ + W+LTAAHC+ + YQIW + Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCM----SDDYQIWLGRHNL 56 Query: 400 --------IHPDLKRIVIEYVDRIIFHENY--NAGTYQNDIALIEMKKDGNKKDCELPRS 449 H + D + + Y +D+ L+ + + D Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 450 IPACVPWSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISN--CSKFYGNRFYE 505 +P P + TC SGWG N +LQ E++L SN C++ Y + E Sbjct: 117 LPTQEP------KLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTE 170 Query: 506 KEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVAN 564 + CA D S C GDSGG L+C G+ SWG C V+TKV Sbjct: 171 FVL-CATHRDDSGSICLGDSGGALICDGVFQ-----GITSWGYSECADFNDNFVFTKVMP 224 Query: 565 YFDWI 569 + WI Sbjct: 225 HKKWI 229 >4GSO-A nrPDB Length = 232 Score = 75.5 bits (184), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 105/239 (43%), Gaps = 22/239 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + P+ +A + G CG I W++TAAHC S + Q+ Sbjct: 1 VLGGDECDINEHPF-LAFLYSHGYFCGLTLINQEWVVTAAHC--DSTNFQMQLGVHSKKV 57 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 ++ D + + ++ I + DI LI++ K + P S+P+ P Sbjct: 58 LNEDEQTRNPK--EKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPP---- 111 Query: 460 LFQPNDTCIVSGWGR-EKDNERVFSLQW-GEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG NE + + + L+ C Y N K CAG + Sbjct: 112 --SVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAY-NGLPAKTTLCAGVLE 168 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWISYHV 573 G D C GDSGGPL+C G+VS+G +CG+ PG+YT V +Y DWI ++ Sbjct: 169 GGKDTCVGDSGGPLICNGQ-----FQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >1NN6-A nrPDB Length = 228 Score = 75.1 bits (183), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 69/242 (28%), Positives = 108/242 (44%), Gaps = 33/242 (13%) Query: 340 IVGGKRAQLGDLPW----QVAIKDASGITCGGIYIGGCWILTAAHCLRASKT---HRYQI 392 I+GG + P+ ++ + CGG I ++LTAAHC S T + I Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 62 Query: 393 WTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 W K VI+ H YN T +DI L+++K+ + P+ Sbjct: 63 TEEEDTW----QKLEVIKQFR----HPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPS 114 Query: 453 CVPWSPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLI--SNCSKFYGNRFYEKEME 509 + P P C V+GWGR +LQ +++L+ CS F R ++ ++ Sbjct: 115 QFNFVP----PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHF---RDFDHNLQ 167 Query: 510 -CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDW 568 C G + A KGDSGGPL+C G+VS+G + KP P V+T++++Y W Sbjct: 168 LCVGNPRKTKSAFKGDSGGPLLCAGVAQ-----GIVSYGRSDAKP--PAVFTRISHYRPW 220 Query: 569 IS 570 I+ Sbjct: 221 IN 222 >1ORF-A nrPDB Length = 234 Score = 74.7 bits (182), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 69/241 (28%), Positives = 106/241 (43%), Gaps = 26/241 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG P+ V + C G I W+LTAAHC +K + + + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC-NLNKRSQVILGAHSITR 59 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEM--KKDGNKKDCELPRSIPACVPWS 457 P K+I++ V + + Y+ T + D+ L+++ K NK L +P Sbjct: 60 EEPT-KQIML--VKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTIL------HLPKK 110 Query: 458 PYLFQPNDTCIVSGWGRE------KDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECA 511 +P C V+GWGR D R + + K+ ++ + + N M CA Sbjct: 111 GDDVKPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCA 170 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-EN-CGKPEFPGVYTKVA-NYFDW 568 G+ G D+C GDSG PL+C GV S+G EN CG P PGVY ++ + +W Sbjct: 171 GSLRGGRDSCNGDSGSPLLCEGV-----FRGVTSFGLENKCGDPRGPGVYILLSKKHLNW 225 Query: 569 I 569 I Sbjct: 226 I 226 >4E7N-A nrPDB Length = 238 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 71/242 (29%), Positives = 100/242 (41%), Gaps = 30/242 (12%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGIT--CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 I+GG + + + VA+ + T CGG I W+LTAAHC R K R ++ Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDR--KNFRIKLGMHSK 58 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD-GNKKDCELPRSIPACVPW 456 + D + V + + +NY + DI LI + N K A Sbjct: 59 KVPNEDEQTRVPKEKFFCLSSKNYT--LWDKDIMLIRLDSPVKNSKHI-------APFSL 109 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEME------- 509 C + GWGR E + V + N ++ R E E Sbjct: 110 PSSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNI--NLLEYEMCRAPYPEFELPATSRT 167 Query: 510 -CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFD 567 CAG +G D CKGDSGGPL+C G+ SWG++ C +P P YTKV ++ D Sbjct: 168 LCAGILEGGKDTCKGDSGGPLICNGQ-----FQGIASWGDDPCAQPHKPAAYTKVFDHLD 222 Query: 568 WI 569 WI Sbjct: 223 WI 224 >1SI5-H nrPDB Length = 240 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 60/225 (26%), Positives = 99/225 (44%), Gaps = 17/225 (7%) Query: 350 DLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIH--PDLKRI 407 ++ W V+++ + CGG I W+LTA C + Y+ W + D +H D K Sbjct: 10 NIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHD-VHGRGDEKCK 68 Query: 408 VIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTC 467 + V ++++ G +D+ L+++ + D +P P +C Sbjct: 69 QVLNVSQLVY------GPEGSDLVLMKLARPAVLDDFVSTIDLPNYGSTIP----EKTSC 118 Query: 468 IVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEME-CAGTYDGSIDACKGD 524 V GWG L+ + ++ N CS+ + + E E CAG C+GD Sbjct: 119 SVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGD 178 Query: 525 SGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 GGPLVC + + + V GV+ G C P PG++ +VA Y WI Sbjct: 179 YGGPLVC-EQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 222 >1BQY-A nrPDB Length = 234 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 63/235 (26%), Positives = 100/235 (42%), Gaps = 20/235 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 + GG + + V + +++G CGG I W++TAAHC ++ +Q+ V Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHC----DSNNFQLLFGVHSK 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + ++ DI LI++ D + + E A + Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKL--DSSVSNSEH----IAPLSLPSS 110 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG+ + ++ + ++ + C Y R CAG Sbjct: 111 PPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQ 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 569 G D C DSGGPL+C N + G+VSWG + CG+P PGVYTKV +Y DWI Sbjct: 171 GGRDTCHFDSGGPLIC---NGI--FQGIVSWGGHPCGQPGEPGVYTKVFDYLDWI 220 >3H7O-A nrPDB Length = 228 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 110/241 (45%), Gaps = 34/241 (14%) Query: 342 GGKRAQLGDLPWQVAIKDASG---ITCGGIYIGGCWILTAAHCLRASKTHRYQI-WTTVV 397 GG++ + +PW VA++ G +TCGG + ++LTAAHC+ K I + + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIE----MKKDGNKKDCELPRSIPAC 453 W P + +V + Y T +NDIA++E +K DG K S PA Sbjct: 62 LWEDPGKSDPYVSHV----YLSFYRQETMENDIAILELSRPLKLDGLK-------SKPAK 110 Query: 454 VPWSPYLFQPNDTCIVSGWG----REKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEME 509 +P + + +VSG+G + + + S Q V L C YG F ++ Sbjct: 111 LPDIEFRPKTGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDL-DECRTKYGPIFLSLQVF 169 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPE-FPGVYTKVANYFDW 568 CA S+++ GD+G P V D + GV ++ +PE P V+TKV +Y W Sbjct: 170 CAQKVGVSLES--GDAGDPTVQQDT-----LVGVAAYFPK--RPEGAPEVFTKVGSYVSW 220 Query: 569 I 569 I Sbjct: 221 I 221 >3S9B-A nrPDB Length = 234 Score = 72.8 bits (177), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 100/235 (42%), Gaps = 20/235 (8%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 +VGG + + P+ VA+ +S I C G I W+LTAAHC R + + + + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKN- 59 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 I + ++I + + + G DI LI +++ P S+P+ Sbjct: 60 --IRNEDEQIRVPRGKYFCLNTKFPNG-LDKDIMLIRLRRPVTYSTHIAPVSLPS----- 111 Query: 458 PYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG+ + ++ + C Y + CAG Sbjct: 112 -RSRGVGSRCRIMGWGKISTTTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILK 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWI 569 G D C GDSGGPL+C + G+V+ G E CG+ P VYTKV +Y +WI Sbjct: 171 GGRDTCHGDSGGPLICNGE-----MHGIVAGGSEPCGQHLKPAVYTKVFDYNNWI 220 >1FUJ-A nrPDB Length = 221 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 93/239 (38%), Gaps = 32/239 (13%) Query: 340 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 IVGG AQ P+ +++ + CGG I ++LTAAHCLR Q V Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIP----QRLVNV 56 Query: 397 VDWIH------PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSI 450 V H P + + V F NY+A NDI LI++ N + Sbjct: 57 VLGAHNVRTQEPTQQHFSVAQV----FLNNYDAENKLNDILLIQLSSPANLSASVATVQL 112 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMEC 510 P P+ Q C+ GWGR ++ +++ + F C Sbjct: 113 PQQDQPVPHGTQ----CLAMGWGRVGAHDP-------PAQVLQELNVTVVTFFCRPHNIC 161 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 C GDSGGPL+C + + V WG C FP +T+VA Y DWI Sbjct: 162 TFVPRRKAGICFGDSGGPLIC--DGIIQGIDSFVIWG--CATRLFPDFFTRVALYVDWI 216 >1FON-A nrPDB Length = 240 Score = 72.0 bits (175), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 73/239 (30%), Positives = 111/239 (46%), Gaps = 39/239 (16%) Query: 353 WQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIV 408 WQV+++ A TCGG I W++TA HC+ S+T YQ+ + + R V Sbjct: 12 WQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRT--YQV-------VLGEYDRSV 62 Query: 409 IEYVDRII--------FHENYNAGTYQ--NDIALIEMKKDGNKKD-CELPRSIPACVPWS 457 +E +++I H +N+ NDIAL+++ + D +L PA Sbjct: 63 LEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGD--- 119 Query: 458 PYLFQPNDT-CIVSGWGREKDNERVFS-LQWGEVKLI--SNCSKF-YGNRFYEKEMECAG 512 PN+ C +SGWGR + LQ + + +CS++ + +K M CAG Sbjct: 120 ---ILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAG 176 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSW--GENCGKPEFPGVYTKVANYFDWI 569 S C GDSGGPL C A+ V GV S+ C + P V+T+V+ + DWI Sbjct: 177 GDTRS--GCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWI 233 >2OCV-B nrPDB Length = 259 Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 82/262 (31%), Positives = 111/262 (42%), Gaps = 44/262 (16%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 IV G A+ G PWQV + K + CG I W+LTAAHC+ Y W Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCIL------YPPWDK-- 52 Query: 398 DWIHPDL------------KRIV--IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKK 442 ++ DL +R V I +++I H YN DIAL+++KK Sbjct: 53 NFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFS 112 Query: 443 DCELPRSIPACVPWSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLIS------- 493 D P +P + L + V+GWG RE + +Q +++++ Sbjct: 113 DYIHPVCLPDKQTVTS-LLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERP 171 Query: 494 NCSKFYGNRFYEKEMECAG-----TYDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWG 547 C R + M CAG T G DAC+GDSGGP V NN Y G+VSWG Sbjct: 172 VCKASTRIRITD-NMFCAGFKVNDTKRG--DACEGDSGGPFVMKSPFNNRWYQMGIVSWG 228 Query: 548 ENCGKPEFPGVYTKVANYFDWI 569 E C + G YT V WI Sbjct: 229 EGCDRKGKYGFYTHVFRLKAWI 250 >5TO3-B nrPDB Length = 409 Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 104/258 (40%), Gaps = 36/258 (13%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHR----YQIW 393 IV G A++G PWQV + K + CG I W+LTAAHCL + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 394 TTVVDWIHPDLKRIV--IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSI 450 + +R + I +++I H YN DIAL+++KK D Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSD----YIH 116 Query: 451 PACVP---WSPYLFQPNDTCIVSGWGREKDN------------ERVFSLQWGEVKLISNC 495 P C+P + L Q V+GWG K+ +V +L E + + Sbjct: 117 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 176 Query: 496 SKFYGNRFYEKEMECAGTYDGS---IDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCG 551 ++ M CAG DAC+GDSGGP V NN Y G+VS G C Sbjct: 177 TRIR----ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCD 232 Query: 552 KPEFPGVYTKVANYFDWI 569 + G YT V WI Sbjct: 233 RDGKYGFYTHVFRLKKWI 250 >1EQ9-A nrPDB Length = 222 Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 68/241 (28%), Positives = 115/241 (47%), Gaps = 24/241 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTTVVD 398 IVGGK A +G P+QV+++ + CG + +LTAAHC+ S +R ++ + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVG-TN 59 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 ++ + V+ + ++NY+ +ND+AL+ + D P + + Sbjct: 60 YLSESGD---VYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLST----ND 112 Query: 459 YLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLISNCSKFYGN---RFYEKEMECAGTY 514 + N C ++GWG + +LQ E++LI + K R + + C T Sbjct: 113 EDLESN-PCTLTGWGSTRLGGNTPNALQ--EIELIVHPQKQCERDQWRVIDSHI-CTLTK 168 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 G AC GDSGGPLV A G+VS+G C E P VYT+V+++ WI+ ++ Sbjct: 169 RGE-GACHGDSGGPLVANGAQ-----IGIVSFGSPCALGE-PDVYTRVSSFVSWINANLK 221 Query: 575 R 575 + Sbjct: 222 K 222 >4Q7Y-A nrPDB Length = 250 Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 62/237 (26%), Positives = 101/237 (42%), Gaps = 19/237 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASKTHRYQIWTTVV 397 I+GG P+ +++ CGG + W+++AAHC R +T + V+ Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 P + + +D + H +Y+ T+ NDI L+ + +P Sbjct: 61 STAEPTQQ---VFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARP 117 Query: 458 PYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 P C V+GWG D E + L +V+++ C+ + M C + Sbjct: 118 PTA---GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCTRSG 173 Query: 515 DGSIDA-CKGDSGGPLVCMDANNVTYVWGVVSW-GENCGKPEFPGVYTKVANYFDWI 569 D C DSGGPLVC + + G+VS+ G CG P+ P VYT+V+ + WI Sbjct: 174 DSHRRGFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 225 >1VR1-H nrPDB Length = 261 Score = 68.9 bits (167), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 80/271 (29%), Positives = 106/271 (39%), Gaps = 58/271 (21%) Query: 340 IVGGKRAQLGDLPWQVAI------KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIW 393 IV G A++G PWQV + CG I W+LTAAHCL Y W Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLL------YPPW 54 Query: 394 TTVVDWIHPDLKRIV--------------IEYVDRIIFHENYN-AGTYQNDIALIEMKKD 438 ++ DL + I +++I H YN DIAL+++KK Sbjct: 55 DK--NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKP 112 Query: 439 GNKKDCELPRSIPACVP---WSPYLFQPNDTCIVSGWGREKDN------------ERVFS 483 D P C+P + L Q V+GWG K+ +V + Sbjct: 113 VAFSDY----IHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVN 168 Query: 484 LQWGEVKLISNCSKFY--GNRF--YEKEMECAGTYDGSIDACKGDSGGPLVCMDA-NNVT 538 L E + + ++ N F Y K E DAC+GDSGGP V NN Sbjct: 169 LPIVERPVCKDSTRIRITDNMFCAYYKPDEGKRG-----DACEGDSGGPFVMKSPFNNRW 223 Query: 539 YVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 Y G+VSWGE C + G YT V WI Sbjct: 224 YQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 254 >2PKA-B nrPDB Length = 152 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 51/156 (32%), Positives = 69/156 (44%), Gaps = 29/156 (18%) Query: 426 YQNDIALIEMKKDGNKKDC----ELPRSIPACVPWSPYLFQPNDTCIVSGWGR----EKD 477 Y +D+ L+ ++ D ELP P TC SGWG D Sbjct: 6 YSHDLMLLRLQSPAKITDAVKVLELPTQEPEL----------GSTCEASGWGSIEPGPDD 55 Query: 478 NERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDAN 535 E +Q ++ L+ N C+ + ++ E M CAG G D C GDSGGPL+C Sbjct: 56 FEFPDEIQCVQLTLLQNTFCADAHPDKVTES-MLCAGYLPGGKDTCMGDSGGPLIC---- 110 Query: 536 NVTYVW-GVVSWGEN-CGKPEFPGVYTKVANYFDWI 569 +W G+ SWG CG P +YTK+ Y DWI Sbjct: 111 --NGMWQGITSWGHTPCGSANKPSIYTKLIFYLDWI 144 >3S69-A nrPDB Length = 234 Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 101/235 (42%), Gaps = 20/235 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + VA +++G C G I W+LTAAHC + + + + V Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKV-- 58 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 ++ D + ++ I N DI LI++ + + +P S+P+ Sbjct: 59 LNEDEQ--TRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPS------S 110 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG + + + L+ + C Y E CAG + Sbjct: 111 PPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 569 G D C GDSGGPL+C G+VS+G + CG+ PGVYTKV +Y WI Sbjct: 171 GGKDTCGGDSGGPLICNGQ-----FQGIVSFGAHPCGQGLKPGVYTKVFDYNHWI 220 >5XRF-A nrPDB Length = 242 Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/216 (27%), Positives = 87/216 (40%), Gaps = 32/216 (14%) Query: 365 CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVD---RIIFHENY 421 C G I W+L AAHC + I+ + I++ D R E+Y Sbjct: 34 CAGTLIHEEWVLAAAHCYKRGLN------------IYLGMHNQSIQFDDEQRRYAIEEHY 81 Query: 422 NAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQP---NDTCIVSGWGREKDN 478 Y+ D L + +KD P S + P C V GWG Sbjct: 82 ----YRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSIGSVCRVMGWGIMSST 137 Query: 479 ERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDA 534 + + + L++ C Y + + CAG +G ID C DSGGPL+C Sbjct: 138 KDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEGGIDTCNQDSGGPLICDGQ 197 Query: 535 NNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWI 569 G+V +G+ C +P PG+YT+V+NY DWI Sbjct: 198 -----FQGIVFFGKYPCAQPNKPGLYTRVSNYNDWI 228 >1AKS-B nrPDB Length = 98 Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 34/77 (44%), Positives = 43/77 (55%), Gaps = 6/77 (7%) Query: 493 SNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGK 552 S+C Y + M C G G D+C+GDSGGP+VC + G+VSWG C + Sbjct: 21 SSCKSSYPGQI-TGNMICVGFLQGGKDSCQGDSGGPVVCNGQ-----LQGIVSWGYGCAQ 74 Query: 553 PEFPGVYTKVANYFDWI 569 PGVYTKV NY +WI Sbjct: 75 KNKPGVYTKVCNYVNWI 91 >2RDL-A nrPDB Length = 226 Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 60/244 (24%), Positives = 102/244 (41%), Gaps = 37/244 (15%) Query: 340 IVGGKRAQLGDLPW----QVAIKDASGITCGGIYIGGCWILTAAHCLRASKT-----HRY 390 I+GG + P+ ++ + C G I +++TAAHC S T H Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 391 QIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKK--DCELPR 448 ++ + V++ H Y+ NDI L+++K+ N LP Sbjct: 61 KVKEDTWQKLE----------VEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPI 110 Query: 449 SIPA-CVPWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLISNCSKFYGNRFYEK 506 S + +P P C GWGR NE +LQ +++++ + + F+++ Sbjct: 111 SAKSNSIP-------PGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQE 163 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 566 C G + KGDSGGPL+C G+ S+ KP P V+T++++Y Sbjct: 164 PQLCVGNPKKIRNVYKGDSGGPLLC-----AGIAQGIASYVLRNAKP--PSVFTRISHYR 216 Query: 567 DWIS 570 WI+ Sbjct: 217 PWIN 220 >1AE5-A nrPDB Length = 225 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 64/252 (25%), Positives = 102/252 (40%), Gaps = 47/252 (18%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG++A+ P+ +I++ CGG I +++TAA C ++ +TVV Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPG----VSTVVLG 56 Query: 400 IHPDLKRIVIEYVDRIIF------HENYNAGTYQNDIALIEMKKDGNKKDCE--LPRSIP 451 + DL+R E R F Y+ ND+ L+++ ++ N LP Sbjct: 57 AY-DLRR--RERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILP---- 109 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEM--- 508 +P + C V+GWG ++ R +S +F ++ Sbjct: 110 --LPLQNATVEAGTRCQVAGWGSQRSGGR-----------LSRFPRFVNVTVTPEDQCRP 156 Query: 509 --ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGK-PEFPGVYTKVAN 564 C G C GD G PLVC GV S+ CG+ P+F +T+VA Sbjct: 157 NNVCTGVLTRRGGICNGDGGTPLVCEG-----LAHGVASFSLGPCGRGPDF---FTRVAL 208 Query: 565 YFDWISYHVGRP 576 + DWI + P Sbjct: 209 FRDWIDGVLNNP 220 >3RU4-E nrPDB Length = 96 Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 6/88 (6%) Query: 484 LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVW 541 LQ + L+SN C K++G + + M CAG + +C GDSGGPLVC T V Sbjct: 6 LQQASLPLLSNTNCKKYWGTKI-KDAMICAGA--SGVSSCMGDSGGPLVCKKNGAWTLV- 61 Query: 542 GVVSWGENCGKPEFPGVYTKVANYFDWI 569 G+VSWG + PGVY +V +W+ Sbjct: 62 GIVSWGSSTCSTSTPGVYARVTALVNWV 89 >5XW8-A nrPDB Length = 133 Score = 59.7 bits (143), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 41/142 (28%), Positives = 65/142 (45%), Gaps = 20/142 (14%) Query: 339 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 +IVGG +P+QV++ S CGG I W+++AAHC ++ + ++ +D Sbjct: 8 KIVGGYTCAANSIPYQVSLNSGSHF-CGGSLINSQWVVSAAHCYKSRI--QVRLGEHNID 64 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKK----DGNKKDCELPRSIPACV 454 + + + I +II H N+N T NDI LI++ + LPRS A Sbjct: 65 VLEGNEQFI---NAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAA- 120 Query: 455 PWSPYLFQPNDTCIVSGWGREK 476 C++SGWG K Sbjct: 121 ---------GTECLISGWGNTK 133 >2JET-C nrPDB Length = 99 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 33/88 (37%), Positives = 49/88 (55%), Gaps = 6/88 (6%) Query: 484 LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVW 541 LQ + ++S +C K +G++ + M CAG +D+C GDSGGPLVC + V + Sbjct: 9 LQQAALPIVSEADCKKSWGSKITDV-MTCAGA--SGVDSCMGDSGGPLVC-QKDGVWTLA 64 Query: 542 GVVSWGENCGKPEFPGVYTKVANYFDWI 569 G+VSWG PGVY++V W+ Sbjct: 65 GIVSWGSGVCSTSTPGVYSRVTALMPWV 92 >1PPF-E nrPDB Length = 218 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 53/232 (22%), Positives = 91/232 (39%), Gaps = 21/232 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG+RA+ P+ V+++ G CG I ++++AAHC+ ++ + Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + R V + + IF Y+ NDI ++++ +PA Sbjct: 61 SRREPTRQV--FAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA----QGR 114 Query: 460 LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSI 518 C+ GWG N + S LQ V ++++ + + C Sbjct: 115 RLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCR--------RSNVCTLVRGRQA 166 Query: 519 DACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWI 569 C GDSG PLVC + G+ S+ C +P + VA + +WI Sbjct: 167 GVCFGDSGSPLVCNG-----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWI 213 >3VGC-B nrPDB Length = 131 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 11/136 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IV G+ A G PWQV+++D +G CGG I W++TAAHC T + D Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC---GVTTSDVVVAGEFD 57 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA-CVPWS 457 ++I + ++ + YN+ T NDI L+++ + +++ A C+P + Sbjct: 58 Q-GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAAS-----FSQTVSAVCLPSA 111 Query: 458 PYLFQPNDTCIVSGWG 473 F TC+ +GWG Sbjct: 112 SDDFAAGTTCVTTGWG 127 >2JET-B nrPDB Length = 128 Score = 55.5 bits (132), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 11/136 (8%) Query: 343 GKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIH 401 G+ A G PWQV+++D +G CGG I W++TAAHC KT + Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC--GVKTSDVVVAGEFDQ--G 56 Query: 402 PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA-CVPWSPYL 460 D + I + + ++ + +N T +NDI L+++ + ++ A C+P Sbjct: 57 SDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKL-----ATPAQFSETVSAVCLPNVDDD 111 Query: 461 FQPNDTCIVSGWGREK 476 F P C +GWG+ K Sbjct: 112 FPPGTVCATTGWGKTK 127 >3F1S-B nrPDB Length = 283 Score = 55.1 bits (131), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 44/137 (32%), Positives = 67/137 (48%), Gaps = 17/137 (12%) Query: 344 KRA-QLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIH 401 KRA L DLPWQV + ++ G CGG+ I ++LT A C S HR T + Sbjct: 56 KRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKC---SLLHRNITVKTYFNRTS 112 Query: 402 PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRS-IPACVP---WS 457 D I I +V H Y+A +ND++L+E+ + + P + +P C P ++ Sbjct: 113 QDPLMIKITHVH---VHMRYDADAGENDLSLLEL-----EWPIQCPGAGLPVCTPEKDFA 164 Query: 458 PYLFQPNDTCIVSGWGR 474 +L P ++SGW R Sbjct: 165 EHLLIPRTRGLLSGWAR 181 >3H5C-B nrPDB Length = 317 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 44/137 (32%), Positives = 67/137 (48%), Gaps = 17/137 (12%) Query: 344 KRA-QLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIH 401 KRA L DLPWQV + ++ G CGG+ I ++LT A C S HR T + Sbjct: 97 KRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKC---SLLHRNITVKTYFNRTS 153 Query: 402 PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRS-IPACVP---WS 457 D I I +V H Y+A +ND++L+E+ + + P + +P C P ++ Sbjct: 154 QDPLMIKITHVH---VHMRYDADAGENDLSLLEL-----EWPIQCPGAGLPVCTPEKDFA 205 Query: 458 PYLFQPNDTCIVSGWGR 474 +L P ++SGW R Sbjct: 206 EHLLIPRTRGLLSGWAR 222 >3H7T-A nrPDB Length = 235 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 65/249 (26%), Positives = 103/249 (41%), Gaps = 52/249 (20%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK----------THR 389 I+GGK++ + PW V + CGG + +++TAA C+ +K ++R Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGSSYR 60 Query: 390 YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMK-----KDGNKKDC 444 T+V+ K+I Y+ R Y+ T QN+ A+IE + D K Sbjct: 61 TTKGTSVM------AKKI---YIVR------YHPLTMQNNYAVIETEMPIKLDDKTTKKI 105 Query: 445 ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI----SNCSKFY- 499 ELP + Y +P+ + +VSGWG +S E +C + Y Sbjct: 106 ELPSLL--------YDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYK 157 Query: 500 ---GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFP 556 +++ + CAG GD+G P V N T V GV S+ + EFP Sbjct: 158 QIEADKYIYDGVFCAGGEYDETYIGYGDAGDPAV----QNGTLV-GVASYISSM-PSEFP 211 Query: 557 GVYTKVANY 565 V+ +V Y Sbjct: 212 SVFLRVGYY 220 >3M0C-C nrPDB Length = 791 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/81 (41%), Positives = 40/81 (49%), Gaps = 3/81 (3%) Query: 217 QKADSPMDDF-FQCVNGKYISQMKACDGINDCGDQSDELCCK--ACQGKGFHCKSGVCIP 273 Q SP F F C++G+ I CDG DC D+SDE C C+ F C G CI Sbjct: 188 QGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIH 247 Query: 274 SQYQCNGEVDCITGEDEVGCA 294 QC+ E DC DEVGC Sbjct: 248 GSRQCDREYDCKDMSDEVGCV 268 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 29/68 (42%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Query: 225 DFFQCVNGKYISQMKACDGINDCGDQSDELCCK--ACQGKGFHCKSGVCIPSQYQCNGEV 282 D F+C +GK IS+ CD DC D SDE C C F C S CIP + C+ + Sbjct: 109 DEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDP 168 Query: 283 DCITGEDE 290 DC G DE Sbjct: 169 DCEDGSDE 176 Score = 52.4 bits (124), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 33/73 (45%), Positives = 40/73 (54%), Gaps = 6/73 (8%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDE---LCCK-ACQGKGFHCKSGV--CIPSQYQCNG 280 FQC +GK IS CDG +C D SDE C C+ F C V CIP ++C+G Sbjct: 29 FQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDG 88 Query: 281 EVDCITGEDEVGC 293 +VDC G DE GC Sbjct: 89 QVDCDNGSDEQGC 101 Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 32/80 (40%), Positives = 38/80 (47%), Gaps = 12/80 (15%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDELC--CKA----------CQGKGFHCKSGVCIPS 274 FQC + I Q+ ACD DC D SDE C+ C FHC SG CI S Sbjct: 150 FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHS 209 Query: 275 QYQCNGEVDCITGEDEVGCA 294 ++C+G DC DE CA Sbjct: 210 SWRCDGGPDCKDKSDEENCA 229 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 26/61 (42%), Positives = 31/61 (50%), Gaps = 2/61 (3%) Query: 235 ISQMKACDGINDCGDQSDELCC--KACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVG 292 I Q CDG DC + SDE C K C F C G CI Q+ C+ + DC+ G DE Sbjct: 80 IPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEAS 139 Query: 293 C 293 C Sbjct: 140 C 140 Score = 30.4 bits (67), Expect = 2.3, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 259 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDE 290 C+ F C+ G CI ++ C+G +C G DE Sbjct: 24 CERNEFQCQDGKCISYKWVCDGSAECQDGSDE 55 >2KAI-A nrPDB Length = 80 Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 4/54 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIW 393 I+GG+ + PWQVAI S CGG+ + W+LTAAHC K Y++W Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHC----KNDNYEVW 50 >1N7D-A nrPDB Length = 699 Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 34/81 (41%), Positives = 40/81 (49%), Gaps = 3/81 (3%) Query: 217 QKADSPMDDF-FQCVNGKYISQMKACDGINDCGDQSDELCCK--ACQGKGFHCKSGVCIP 273 Q SP F F C++G+ I CDG DC D+SDE C C+ F C G CI Sbjct: 170 QGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIH 229 Query: 274 SQYQCNGEVDCITGEDEVGCA 294 QC+ E DC DEVGC Sbjct: 230 GSRQCDREYDCKDMSDEVGCV 250 Score = 52.8 bits (125), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 29/68 (42%), Positives = 35/68 (51%), Gaps = 2/68 (2%) Query: 225 DFFQCVNGKYISQMKACDGINDCGDQSDELCCK--ACQGKGFHCKSGVCIPSQYQCNGEV 282 D F+C +GK IS+ CD DC D SDE C C F C S CIP + C+ + Sbjct: 91 DEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDP 150 Query: 283 DCITGEDE 290 DC G DE Sbjct: 151 DCEDGSDE 158 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 33/73 (45%), Positives = 40/73 (54%), Gaps = 6/73 (8%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDE---LCCK-ACQGKGFHCKSGV--CIPSQYQCNG 280 FQC +GK IS CDG +C D SDE C C+ F C V CIP ++C+G Sbjct: 11 FQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDG 70 Query: 281 EVDCITGEDEVGC 293 +VDC G DE GC Sbjct: 71 QVDCDNGSDEQGC 83 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/80 (40%), Positives = 38/80 (47%), Gaps = 12/80 (15%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDELC--CKA----------CQGKGFHCKSGVCIPS 274 FQC + I Q+ ACD DC D SDE C+ C FHC SG CI S Sbjct: 132 FQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHS 191 Query: 275 QYQCNGEVDCITGEDEVGCA 294 ++C+G DC DE CA Sbjct: 192 SWRCDGGPDCKDKSDEENCA 211 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 26/63 (41%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Query: 233 KYISQMKACDGINDCGDQSDELCC--KACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDE 290 + I Q CDG DC + SDE C K C F C G CI Q+ C+ + DC+ G DE Sbjct: 60 RCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDE 119 Query: 291 VGC 293 C Sbjct: 120 ASC 122 Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 259 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDE 290 C+ F C+ G CI ++ C+G +C G DE Sbjct: 6 CERNEFQCQDGKCISYKWVCDGSAECQDGSDE 37 >5B4X-B nrPDB Length = 570 Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 29/68 (42%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Query: 225 DFFQCVNGKYISQMKACDGINDCGDQSDELCC--KACQGKGFHCKSGVCIPSQYQCNGEV 282 D FQC N + I + CD +DC D SDE C K C F C +G CI +++C+GE Sbjct: 10 DQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEE 69 Query: 283 DCITGEDE 290 +C G DE Sbjct: 70 ECPDGSDE 77 Score = 51.2 bits (121), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 35/94 (37%), Positives = 47/94 (50%), Gaps = 10/94 (10%) Query: 211 DVVCYTQKADSP----MDDFFQCVNGKYISQMKACDGINDCGDQSDE---LCCK-ACQGK 262 D + ++ + D P D F C NG I + CDG +C D SDE C K C + Sbjct: 31 DCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAE 90 Query: 263 GFHC--KSGVCIPSQYQCNGEVDCITGEDEVGCA 294 C S C+P+ ++C+GE DC G DE GCA Sbjct: 91 KLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCA 124 Score = 45.1 bits (105), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 4/57 (7%) Query: 241 CDGINDCGDQSDELCCKA----CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 CDG DC +DE C C+G F C G C+ + CN E DC G DE GC Sbjct: 108 CDGEKDCEGGADEAGCATSLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 164 Score = 33.9 bits (76), Expect = 0.21, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 22/37 (59%) Query: 257 KACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 K C+ F C++ CIPS ++C+ + DC+ DE C Sbjct: 5 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDC 41 >1BBR-H nrPDB Length = 150 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/158 (31%), Positives = 69/158 (43%), Gaps = 30/158 (18%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWT--- 394 IV G+ A++G PWQV + K + CG I W+LTAAHCL Y W Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL------LYPPWDKNF 54 Query: 395 TVVDWI-------HPDLKRIV--IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDC 444 TV D + +R V I +D+I H YN DIAL+++ K+ Sbjct: 55 TVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKL-----KRPI 109 Query: 445 ELPRSI-PACVP---WSPYLFQPNDTCIVSGWGREKDN 478 EL I P C+P + L V+GWG ++ Sbjct: 110 ELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >1BBR-E nrPDB Length = 109 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 32/72 (44%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 508 MECAGTYDGSI---DACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEFPGVYTKVA 563 M CAG G DAC+GDSGGP V NN Y G+VSWGE C + G YT V Sbjct: 35 MFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVF 94 Query: 564 NYFDWISYHVGR 575 WI + R Sbjct: 95 RLKKWIQKVIDR 106 >1RIW-B nrPDB Length = 147 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 47/158 (29%), Positives = 65/158 (41%), Gaps = 32/158 (20%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 IV G A++G PWQV + K + CG I W+LTAAHCL Y W Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL------LYPPWDK-- 52 Query: 398 DWIHPDLKRIV--------------IEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKK 442 ++ DL + I +++I H YN DIAL+++KK Sbjct: 53 NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFS 112 Query: 443 DCELPRSIPACVP---WSPYLFQPNDTCIVSGWGREKD 477 D P C+P + L Q V+GWG K+ Sbjct: 113 DY----IHPVCLPDRETAASLLQAGYKGRVTGWGNLKE 146 >2I6S-A nrPDB Length = 517 Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 61/244 (25%), Positives = 92/244 (37%), Gaps = 45/244 (18%) Query: 341 VGGKRAQLGD---LPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTH---RYQIWT 394 VG A D PW V IK S TC G I W+LTAAHC R H R + Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD 289 Query: 395 TVVDWIHPDL--KRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 W L K ++ D Y +DIAL+++ + P +P Sbjct: 290 PKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPC 349 Query: 453 CVPWSPYLFQPN-DTCIVSGWGREKDNERV----------------------FSLQWGE- 488 + + L +P TC R+ +NE + ++W Sbjct: 350 TMEANLALRRPQGSTC------RDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSC 403 Query: 489 VKLISNCSKFYGNRFYEKEME-----CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGV 543 +++S + N +E+ C+GT + CKG+SGG V ++ + G+ Sbjct: 404 AEVVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE-SPCKGESGGA-VFLERRFRFFQVGL 461 Query: 544 VSWG 547 VSWG Sbjct: 462 VSWG 465 >2HNT-F nrPDB Length = 105 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 26/52 (50%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Query: 519 DACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 DAC+GDSGGP V NN Y G+VSWGE C + G YT V WI Sbjct: 45 DACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 96 >1DLE-A nrPDB Length = 298 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 62/244 (25%), Positives = 95/244 (38%), Gaps = 65/244 (26%) Query: 352 PWQV---AIKDASG-ITCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTTVVDWIHPDLKR 406 PWQ I+ + G +C G + ++LTAAHC K H ++ V DL+ Sbjct: 28 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV---SVGGEKRDLE- 83 Query: 407 IVIEYVDRIIFHENYN------AGT---YQNDIALIEMKK----------------DGNK 441 ++ ++FH NYN AG Y D+ALI++K +G Sbjct: 84 -----IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTT 138 Query: 442 KDCELPRSIPACVPWSPYLFQPND--TCIVSGWGREKDNERVFSLQWGEVK--------- 490 + LP + C L D VS ++ + V+ ++ G+ K Sbjct: 139 RALRLPPTT-TCQQQKEELLPAQDIKALFVSEEEKKLTRKEVY-IKNGDKKGSCERDAQY 196 Query: 491 -----LISNCSKFYGNRFYEKEMECAGTYDGSID--ACKGDSGGPLVCMDANNVTYVWGV 543 + + S+ RF C G D C+GDSGGPL+ + V GV Sbjct: 197 APGYDKVKDISEVVTPRFL-----CTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV-GV 250 Query: 544 VSWG 547 +SWG Sbjct: 251 ISWG 254 >2HNT-C nrPDB Length = 70 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 2/45 (4%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCL 382 IV G A++G PWQV + K + CG I W+LTAAHCL Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCL 45 >2OK5-A nrPDB Length = 752 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 60/244 (24%), Positives = 91/244 (37%), Gaps = 65/244 (26%) Query: 352 PWQV---AIKDASGI-TCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTTVVDWIHPDLKR 406 PWQ I+ + G +C G + ++LTAAHC K H ++ V DL+ Sbjct: 479 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV---SVGGEKRDLE- 534 Query: 407 IVIEYVDRIIFHENYN------AGT---YQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 ++ ++FH NYN AG Y D+ALI++K P +P + Sbjct: 535 -----IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTT 589 Query: 458 PYL-FQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFY-----------E 505 L P TC ++ E + Q + +S K + E Sbjct: 590 RALRLPPTTTC-------QQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCE 642 Query: 506 KEMECAGTYDGSID----------------------ACKGDSGGPLVCMDANNVTYVWGV 543 ++ + A YD D C+GDSGGPL+ + V GV Sbjct: 643 RDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV-GV 701 Query: 544 VSWG 547 +SWG Sbjct: 702 ISWG 705 >2WIN-I nrPDB Length = 507 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 62/244 (25%), Positives = 95/244 (38%), Gaps = 65/244 (26%) Query: 352 PWQV---AIKDASGI-TCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTTVVDWIHPDLKR 406 PWQ I+ + G +C G + ++LTAAHC K H ++ V DL+ Sbjct: 235 PWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV---SVGGEKRDLE- 290 Query: 407 IVIEYVDRIIFHENYN------AGT---YQNDIALIEMKK----------------DGNK 441 ++ ++FH NYN AG Y D+ALI++K +G Sbjct: 291 -----IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTT 345 Query: 442 KDCELPRSIPACVPWSPYLFQPND--TCIVSGWGREKDNERVFSLQWGEVK--------- 490 + LP + C L D VS ++ + V+ ++ G+ K Sbjct: 346 RALRLPPTT-TCQQQKEELLPAQDIKALFVSEEEKKLTRKEVY-IKNGDKKGSCERDAQY 403 Query: 491 -----LISNCSKFYGNRFYEKEMECAGTYDGSID--ACKGDSGGPLVCMDANNVTYVWGV 543 + + S+ RF C G D C+GDSGGPL+ + V GV Sbjct: 404 APGYDKVKDISEVVTPRFL-----CTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV-GV 457 Query: 544 VSWG 547 +SWG Sbjct: 458 ISWG 461 >5ZE3-A nrPDB Length = 457 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 114 VSLKHGNTDSEGIVEVKLVDQDKTM---FICKSSWSMREANVAC--LDLGFQQGADTQRR 168 + L G EG VEV LV++ ++ +C +W + EA V C L LGF A + Sbjct: 118 LRLNGGRNPYEGRVEV-LVERQGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETW 176 Query: 169 FKLSDLSINSTECLHVHCRGLETSLAECTFTKRRTM----GYQDFADVVCYTQKAD 220 + D++ N V C G E SLA C G Q A V C D Sbjct: 177 YWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPD 232 Score = 36.2 bits (82), Expect = 0.037, Method: Compositional matrix adjust. Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 4/104 (3%) Query: 114 VSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSD 173 V L+ G EG VEV + + +C W + A+V C +LGF + +L Sbjct: 9 VRLRGGAYIGEGRVEV--LKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 66 Query: 174 LSINSTECLHVHCRGLETSLAECTFT-KRRTMGYQDFADVVCYT 216 I + C G E S+ +C F + + +++ A V C T Sbjct: 67 -GIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNT 109 >1EPT-B nrPDB Length = 82 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 14/67 (20%) Query: 414 RIIFHENYNAGTYQNDIALIEMKK----DGNKKDCELPRSIPACVPWSPYLFQPNDTCIV 469 +II H N+N T NDI LI++ + LPRS A C++ Sbjct: 26 KIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAA----------GTECLI 75 Query: 470 SGWGREK 476 SGWG K Sbjct: 76 SGWGNTK 82 >4A5W-B nrPDB Length = 913 Score = 34.7 bits (78), Expect = 0.11, Method: Compositional matrix adjust. Identities = 18/44 (40%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Query: 213 VCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCC 256 +C ++AD + F+C +G+ I++ C+G NDCGD SDE C Sbjct: 111 LCKIEEAD--CKNKFRCDSGRCIARKLECNGENDCGDNSDERDC 152 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 259 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASV 299 C+ K F C SG CI + +CNGE DC DE C +V Sbjct: 119 CKNK-FRCDSGRCIARKLECNGENDCGDNSDERDCGRTKAV 158 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 14/70 (20%) Query: 42 SCDKVFCQPWQRCIEGT--CVCKLPYQCPKNGTAV------CATNRRSF------PTYCQ 87 SC C W++C T CVC LP QC K G + +T+ ++ C Sbjct: 840 SCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCA 899 Query: 88 QKSLECLHPG 97 + +E LHPG Sbjct: 900 NRKMEILHPG 909 >5H7V-A nrPDB Length = 421 Score = 34.7 bits (78), Expect = 0.12, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%) Query: 240 ACDGINDCG-DQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFAS 298 AC G+ ++ +C CQ F C +G CI S +C+ +C DE C + S Sbjct: 269 ACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTS 328 Query: 299 VTQEETEI 306 E I Sbjct: 329 GFDELQRI 336 >3OJY-A nrPDB Length = 554 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 251 SDELCCKACQ-GKGFHCK-SGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQE 302 S C + Q G+ F CK +G C+ CNG+ DC+ G DE C ++ ++ Sbjct: 56 SSTTCVRQAQCGQDFQCKETGRCLKRHLVCNGDQDCLDGSDEDDCEDVRAIDED 109 >6H03-G nrPDB Length = 538 Score = 34.3 bits (77), Expect = 0.17, Method: Compositional matrix adjust. Identities = 16/32 (50%), Positives = 20/32 (62%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDELCCKA 258 FQC G+ I C+G NDCGD SDE C++ Sbjct: 84 FQCSTGRCIKMRLRCNGDNDCGDFSDEDDCES 115 Score = 33.5 bits (75), Expect = 0.25, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 10/84 (11%) Query: 214 CYTQKADSPMDDFFQCVNGKY----ISQMKACDGINDCGDQSDELCCKACQGKGFHCKSG 269 C Q S + F NGK + + C C D D+ G F C +G Sbjct: 36 CLRQMFRSRSIEVFGQFNGKRCTDAVGDRRQCVPTEPCEDAEDDC------GNDFQCSTG 89 Query: 270 VCIPSQYQCNGEVDCITGEDEVGC 293 CI + +CNG+ DC DE C Sbjct: 90 RCIKMRLRCNGDNDCGDFSDEDDC 113 >6CXO-A nrPDB Length = 529 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 16/30 (53%), Positives = 19/30 (63%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDELCC 256 FQC G+ I + C+G NDCGD SDE C Sbjct: 84 FQCETGRCIKRRLLCNGDNDCGDYSDENDC 113 Score = 32.0 bits (71), Expect = 0.86, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 18/33 (54%) Query: 261 GKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 G F C++G CI + CNG+ DC DE C Sbjct: 81 GNDFQCETGRCIKRRLLCNGDNDCGDYSDENDC 113 >6H03-D nrPDB Length = 821 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 5/64 (7%) Query: 48 CQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRS---FP-TYCQQKSLECLHPGTKFLNN 103 CQ W++ CVCK+PY+C + VCA + RS P T C+ L C Sbjct: 680 CQRWEKLQNSRCVCKMPYECGPS-LDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGR 738 Query: 104 GTCT 107 +CT Sbjct: 739 DSCT 742 >2WCY-A nrPDB Length = 155 Score = 32.3 bits (72), Expect = 0.60, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 5/64 (7%) Query: 48 CQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRS---FP-TYCQQKSLECLHPGTKFLNN 103 CQ W++ CVCK+PY+C + VCA + RS P T C+ L C Sbjct: 14 CQRWEKLQNSRCVCKMPYECGPS-LDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGR 72 Query: 104 GTCT 107 +CT Sbjct: 73 DSCT 76 >3OJY-B nrPDB Length = 537 Score = 32.3 bits (72), Expect = 0.61, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 19/26 (73%) Query: 232 GKYISQMKACDGINDCGDQSDELCCK 257 G+ +++ C+G NDCGDQSDE C+ Sbjct: 77 GRCVNRRLLCNGDNDCGDQSDEANCR 102 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2XRC-A nrPDB 895 0.0 5O32-I nrPDB 350 1e-96 2F83-A nrPDB 316 2e-86 6I44-A nrPDB 277 9e-75 5TJX-A nrPDB 269 3e-72 5GVT-A nrPDB 268 4e-72 3W94-A nrPDB 265 4e-71 4DGJ-A nrPDB 259 2e-69 1UTJ-A nrPDB 256 1e-68 4AN7-A nrPDB 256 2e-68 1EKB-B nrPDB 254 9e-68 3P8G-A nrPDB 254 1e-67 1F7Z-A nrPDB 253 2e-67 5FXL-A nrPDB 253 2e-67 6AOD-C nrPDB 252 3e-67 4WWY-A nrPDB 251 5e-67 5C67-A nrPDB 250 9e-67 5UGG-A nrPDB 250 1e-66 1YC0-A nrPDB 249 2e-66 1A0J-A nrPDB 249 2e-66 1FXY-A nrPDB 249 2e-66 3T2N-A nrPDB 249 2e-66 4MPW-A nrPDB 248 4e-66 3LC3-A nrPDB 248 4e-66 3DFJ-A nrPDB 248 5e-66 4KKD-A nrPDB 248 7e-66 3E0N-B nrPDB 246 1e-65 1X7A-C nrPDB 246 2e-65 2F91-A nrPDB 246 2e-65 3K65-B nrPDB 245 3e-65 2OQ5-A nrPDB 245 4e-65 1PYT-D nrPDB 245 4e-65 1MKW-K nrPDB 243 1e-64 1LTO-A nrPDB 243 2e-64 4H4F-A nrPDB 242 3e-64 4NFE-A nrPDB 242 3e-64 1FIW-A nrPDB 242 4e-64 3NXP-A nrPDB 241 4e-64 1BDA-A nrPDB 241 4e-64 1P57-B nrPDB 241 7e-64 2CGA-A nrPDB 241 7e-64 1SGF-G nrPDB 240 1e-63 4DUR-A nrPDB 239 2e-63 1ETT-H nrPDB 239 2e-63 1ELV-A nrPDB 239 3e-63 1FIZ-A nrPDB 238 4e-63 2OCV-B nrPDB 238 4e-63 1VR1-H nrPDB 238 4e-63 1BRU-P nrPDB 238 7e-63 4IGD-A nrPDB 238 7e-63 1C5M-D nrPDB 237 1e-62 2R0L-A nrPDB 236 2e-62 4NZQ-A nrPDB 236 2e-62 4Z6A-H nrPDB 236 2e-62 4IW4-E nrPDB 236 3e-62 1SC8-U nrPDB 234 6e-62 3F6U-H nrPDB 234 9e-62 1A5I-A nrPDB 234 9e-62 1EUF-A nrPDB 233 2e-61 1FI8-A nrPDB 233 2e-61 3QUM-P nrPDB 232 3e-61 1KIG-H nrPDB 232 4e-61 4J1Y-A nrPDB 231 5e-61 6QHB-A nrPDB 230 1e-60 2TLD-E nrPDB 230 2e-60 3BSQ-A nrPDB 229 4e-60 1Q3X-A nrPDB 228 4e-60 1SPJ-A nrPDB 227 9e-60 5UBM-A nrPDB 227 1e-59 1AO5-A nrPDB 226 2e-59 4XDE-A nrPDB 225 3e-59 2EEK-A nrPDB 225 5e-59 1NPM-A nrPDB 224 7e-59 1ZJK-A nrPDB 224 1e-58 5MS3-A nrPDB 223 1e-58 5LHN-A nrPDB 223 2e-58 4FXG-H nrPDB 223 2e-58 1FDP-A nrPDB 222 4e-58 5ZFH-A nrPDB 222 4e-58 3TK9-A nrPDB 221 7e-58 1MD7-A nrPDB 220 1e-57 4DJZ-B nrPDB 220 2e-57 1MZD-A nrPDB 219 2e-57 2OLG-A nrPDB 219 4e-57 5TO3-B nrPDB 218 6e-57 1NN6-A nrPDB 218 7e-57 2PSX-A nrPDB 218 8e-57 1SGF-A nrPDB 218 9e-57 1GPZ-A nrPDB 217 9e-57 1TON-A nrPDB 217 9e-57 2V35-A nrPDB 217 1e-56 2BDH-A nrPDB 216 2e-56 1ELT-A nrPDB 214 6e-56 1IAU-A nrPDB 214 6e-56 5FCR-A nrPDB 213 2e-55 1YM0-A nrPDB 212 2e-55 5KWM-A nrPDB 212 3e-55 1OP0-A nrPDB 212 4e-55 3RP2-A nrPDB 211 7e-55 1FUJ-A nrPDB 211 9e-55 1BQY-A nrPDB 210 1e-54 4GSO-A nrPDB 210 1e-54 3G01-A nrPDB 210 1e-54 3S9B-A nrPDB 209 2e-54 4BXW-A nrPDB 207 1e-53 4WJG-C nrPDB 207 1e-53 2QY0-B nrPDB 207 1e-53 1KYN-A nrPDB 207 1e-53 3S69-A nrPDB 206 2e-53 2AIQ-A nrPDB 206 2e-53 1FON-A nrPDB 206 2e-53 1GVZ-A nrPDB 206 2e-53 4X0L-C nrPDB 206 3e-53 1AZZ-A nrPDB 206 3e-53 2XXL-A nrPDB 206 3e-53 4F4O-C nrPDB 205 4e-53 3I77-A nrPDB 204 1e-52 4Q7Y-A nrPDB 204 1e-52 2ZKS-A nrPDB 203 1e-52 2B9L-A nrPDB 203 2e-52 5LPF-A nrPDB 202 3e-52 4E7N-A nrPDB 202 5e-52 1ORF-A nrPDB 201 8e-52 1PQ7-A nrPDB 201 9e-52 2RDL-A nrPDB 200 2e-51 3BEU-A nrPDB 199 4e-51 6BQM-A nrPDB 198 5e-51 2FMJ-A nrPDB 197 9e-51 4LK4-A nrPDB 196 3e-50 2HLC-A nrPDB 194 1e-49 1EQ9-A nrPDB 189 4e-48 1AE5-A nrPDB 188 5e-48 2ASU-B nrPDB 184 7e-47 1PPF-E nrPDB 184 1e-46 1SI5-H nrPDB 183 2e-46 5XRF-A nrPDB 182 3e-46 1M9U-A nrPDB 180 1e-45 3H7O-A nrPDB 154 1e-37 5ZE3-A nrPDB 153 2e-37 2PKA-B nrPDB 151 9e-37 3H7T-A nrPDB 148 5e-36 5XW8-A nrPDB 143 2e-34 1RIW-B nrPDB 141 1e-33 3VGC-B nrPDB 139 3e-33 2JET-B nrPDB 138 8e-33 1BBR-H nrPDB 137 2e-32 2WIN-I nrPDB 133 2e-31 2I6S-A nrPDB 130 2e-30 1DLE-A nrPDB 128 8e-30 2OK5-A nrPDB 127 1e-29 1AKS-B nrPDB 120 2e-27 3M0C-C nrPDB 117 1e-26 1N7D-A nrPDB 116 2e-26 1BBR-E nrPDB 113 2e-25 2HNT-F nrPDB 111 9e-25 5B4X-B nrPDB 108 8e-24 3RU4-E nrPDB 101 1e-21 2JET-C nrPDB 99 5e-21 2KAI-A nrPDB 97 1e-20 3F1S-B nrPDB 95 1e-19 3H5C-B nrPDB 94 2e-19 2HNT-C nrPDB 69 4e-12 Sequences not found previously or not previously below threshold: 1EPT-B nrPDB 84 2e-16 2HNT-E nrPDB 77 1e-14 2J8L-A nrPDB 69 5e-12 6H03-G nrPDB 52 5e-07 6CXO-A nrPDB 48 1e-05 5H7V-A nrPDB 48 1e-05 3OJY-A nrPDB 47 2e-05 1P3E-A nrPDB 47 3e-05 4A5W-B nrPDB 44 2e-04 3OJY-B nrPDB 42 8e-04 6H03-D nrPDB 39 0.009 5IEE-B nrPDB 37 0.020 2WCY-A nrPDB 35 0.073 2OUA-A nrPDB 35 0.13 4JCN-A nrPDB 34 0.21 5ILB-A nrPDB 33 0.38 4FLN-A nrPDB 33 0.38 1XFE-A nrPDB 32 0.91 1NUB-A nrPDB 30 2.4 3SC7-X nrPDB 30 3.4 3CMG-A nrPDB 29 6.0 1P7O-A nrPDB 29 6.5 1DT2-A nrPDB 29 6.5 2EA3-A nrPDB 29 6.5 5WJF-A nrPDB 28 7.6 5WZN-A nrPDB 28 9.6 2PFE-A nrPDB 28 9.7 >2XRC-A nrPDB Length = 565 Score = 895 bits (2314), Expect = 0.0, Method: Composition-based stats. Identities = 564/565 (99%), Positives = 564/565 (99%) Query: 19 KVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATN 78 KVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATN Sbjct: 1 KVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATN 60 Query: 79 RRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTM 138 RRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTM Sbjct: 61 RRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTM 120 Query: 139 FICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTF 198 FICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTF Sbjct: 121 FICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTF 180 Query: 199 TKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKA 258 TKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKA Sbjct: 181 TKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKA 240 Query: 259 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRI 318 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASV QEETEILTADMDAERRRI Sbjct: 241 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVAQEETEILTADMDAERRRI 300 Query: 319 KSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTA 378 KSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTA Sbjct: 301 KSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTA 360 Query: 379 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD 438 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD Sbjct: 361 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD 420 Query: 439 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKF 498 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKF Sbjct: 421 GNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKF 480 Query: 499 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV 558 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV Sbjct: 481 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGV 540 Query: 559 YTKVANYFDWISYHVGRPFISQYNV 583 YTKVANYFDWISYHVGRPFISQYNV Sbjct: 541 YTKVANYFDWISYHVGRPFISQYNV 565 >5O32-I nrPDB Length = 244 Score = 350 bits (897), Expect = 1e-96, Method: Composition-based stats. Identities = 244/244 (100%), Positives = 244/244 (100%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 460 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSID 519 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSID Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSID 180 Query: 520 ACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFIS 579 ACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFIS Sbjct: 181 ACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFIS 240 Query: 580 QYNV 583 QYNV Sbjct: 241 QYNV 244 >2F83-A nrPDB Length = 625 Score = 316 bits (810), Expect = 2e-86, Method: Composition-based stats. Identities = 109/331 (32%), Positives = 148/331 (44%), Gaps = 27/331 (8%) Query: 250 QSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTA 309 +S E C K C C+ P+Q CN E + C S T+IL Sbjct: 312 KSHEACQKLCTN-AVRCQFFTYTPAQASCN--------EGKGKCYLKLSSNGSPTKILHG 362 Query: 310 DMDAERRRIKSLLPKLSCGVKNRMHIRRK-RIVGGKRAQLGDLPWQVAIKDAS---GITC 365 R I +L C + N + K RIVGG + G+ PWQV + S C Sbjct: 363 -----RGGISGYTLRL-CKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLC 416 Query: 366 GGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGT 425 GG IG WILTAAHC ++ + + + + V II H+ Y Sbjct: 417 GGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAE 476 Query: 426 YQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV-FSL 484 DIAL++++ N D + P C+P C V+GWG K +++ +L Sbjct: 477 SGYDIALLKLETTVNYTDSQR----PICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTL 532 Query: 485 QWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWG 542 Q ++ L++N C K Y +M CAG +G DACKGDSGGPL C N V ++ G Sbjct: 533 QKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCK-HNEVWHLVG 591 Query: 543 VVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 + SWGE C + E PGVYT V Y DWI Sbjct: 592 ITSWGEGCAQRERPGVYTNVVEYVDWILEKT 622 Score = 36.2 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 32/108 (29%), Gaps = 22/108 (20%) Query: 233 KYISQMKACDGI------------NDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNG 280 + Q+ AC+ N +S + C + C HC Q+ Sbjct: 102 QCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDD-VHCHFFTYATRQF---- 156 Query: 281 EVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRIKSL-LPKLSC 327 + E C + T T I D +KS L L+C Sbjct: 157 ----PSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLAC 200 >6I44-A nrPDB Length = 627 Score = 277 bits (709), Expect = 9e-75, Method: Composition-based stats. Identities = 97/327 (29%), Positives = 137/327 (41%), Gaps = 27/327 (8%) Query: 255 CCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAE 314 C + C K C+ C E C S+ T I + Sbjct: 307 CQETCT-KMIRCQFFTYSLLPEDCKAEA--------CKCFLRLSMDGSPTRIAYGTQGSS 357 Query: 315 RRRIKSLLP--KLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIK---DASGITCGGIY 369 ++ C RIVGG ++ G+ PWQV+++ A CGG Sbjct: 358 GYSLRLCNTGDNSVC-----TTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSL 412 Query: 370 IGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQND 429 IG W+LTAAHC + + + K + II H+NY +D Sbjct: 413 IGHQWVLTAAHCFDGLPLQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHD 472 Query: 430 IALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGE 488 IALI+++ + + P C+P C V+GWG + + + LQ Sbjct: 473 IALIKLQAPLQYTEFQK----PICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVN 528 Query: 489 VKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSW 546 + L++N C K Y + + M CAG +G DACKGD+GGPLVC N + + G+ SW Sbjct: 529 IPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDAGGPLVCK-HNGMWRLVGITSW 587 Query: 547 GENCGKPEFPGVYTKVANYFDWISYHV 573 GE C + E PGVYTKVA Y DWI Sbjct: 588 GEGCARREQPGVYTKVAEYMDWILEKT 614 >5TJX-A nrPDB Length = 263 Score = 269 bits (687), Expect = 3e-72, Method: Composition-based stats. Identities = 88/241 (36%), Positives = 121/241 (50%), Gaps = 11/241 (4%) Query: 339 RIVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 RIVGG + G+ PWQV+++ A CGG IG W+LTAAHC + Sbjct: 15 RIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 74 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + + K + II H+NY +DIALI+++ + + P S+P+ Sbjct: 75 GILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPS--- 131 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAG 512 C V+GWG K+ + + LQ + L++N C K Y + + M CAG Sbjct: 132 -KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 190 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYH 572 +G DACKGDSGGPLVC N + + G+ SWGE C + E PGVYTKVA Y DWI Sbjct: 191 YKEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 249 Query: 573 V 573 Sbjct: 250 T 250 >5GVT-A nrPDB Length = 250 Score = 268 bits (685), Expect = 4e-72, Method: Composition-based stats. Identities = 86/240 (35%), Positives = 118/240 (49%), Gaps = 11/240 (4%) Query: 340 IVGGKRAQLGDLPWQVAIKD---ASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 IVGG A LG+ PWQV+++ + CGG IG W+LTAAHC Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + + K + +I H+ Y DIALI+++ N + + P S+P+ Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 457 SPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 + C V+GWG K+ E LQ + L+ N C K Y + K+M CAG Sbjct: 121 NTIY----TNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGY 176 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 +G DACKGDSGGPLVC + + G+ SWGE C + + PGVYTKV+ Y DWI Sbjct: 177 KEGGTDACKGDSGGPLVCK-HSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWILEKT 235 >3W94-A nrPDB Length = 235 Score = 265 bits (677), Expect = 4e-71, Method: Composition-based stats. Identities = 78/238 (32%), Positives = 121/238 (50%), Gaps = 10/238 (4%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHR--YQIWTTVV 397 +VGG A+ G PW V++ CG IG W+LTAAHC+ TH + + Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 + + + I VDRII ++NYN T + DIA++ +++ N + +P C+ Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWV----LPVCLASE 116 Query: 458 PYLFQPNDTCIVSGWGREKDNER-VFSLQWGEVKLI--SNCSKFYGNRFYEKEMECAGTY 514 F C ++GWGR+ + LQ EV L+ C + + M CAG Sbjct: 117 DQHFPAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYP 176 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYH 572 +G +D+C+GDSGGPL+C++ + GV S+G CG+PE PG Y +V+ + WI+ Sbjct: 177 EGGVDSCQGDSGGPLMCLEDA-RWTLIGVTSFGVGCGRPERPGAYARVSAFTSWIAET 233 >4DGJ-A nrPDB Length = 235 Score = 259 bits (662), Expect = 2e-69, Method: Composition-based stats. Identities = 74/237 (31%), Positives = 115/237 (48%), Gaps = 10/237 (4%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK--THRYQIWTTVV 397 IVGG A+ G PW V + + CG + W+++AAHC+ ++ + Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 + + V +D I+ + +YN NDIA++ ++ N D P S+P Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLP----EE 116 Query: 458 PYLFQPNDTCIVSGWGR-EKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 +F P C ++GWG LQ +V L+SN C + + M CAG Sbjct: 117 NQVFPPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYE 176 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 +G ID+C+GDSGGPL+C + NN ++ GV S+G C P PGVY +V+ + +WI Sbjct: 177 EGGIDSCQGDSGGPLMCQE-NNRWFLAGVTSFGYECALPNRPGVYARVSRFTEWIQS 232 >1UTJ-A nrPDB Length = 242 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 72/239 (30%), Positives = 110/239 (46%), Gaps = 21/239 (8%) Query: 338 KRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 +IVGG + P QV++ ++ CGG + W+++AAHC ++ R ++ Sbjct: 19 DKIVGGYECKPYSQPHQVSL-NSGYHFCGGSLVNENWVVSAAHCYKS----RVEVRLGEH 73 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 + + I R+I H NY++ NDI LI++ K P ++P Sbjct: 74 NIKVTEGSEQFISS-SRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPTSCA-- 130 Query: 458 PYLFQPNDTCIVSGWGRE-KDNERVFSLQWGEVKLIS--NCSKFYGNRFYEKEMECAGTY 514 C VSGWG LQ + ++S +C+ Y M CAG Sbjct: 131 ----PAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGMI-TNAMFCAGYL 185 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 +G D+C+GDSGGP+VC + GVVSWG C +P PGVY KV + DW++ + Sbjct: 186 EGGKDSCQGDSGGPVVCNGE-----LQGVVSWGYGCAEPGNPGVYAKVCIFNDWLTSTM 239 >4AN7-A nrPDB Length = 231 Score = 256 bits (654), Expect = 2e-68, Method: Composition-based stats. Identities = 74/246 (30%), Positives = 112/246 (45%), Gaps = 22/246 (8%) Query: 332 RMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQ 391 +IVGG +P+QV++ ++ CGG I W+++AAHC ++ R Q Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKS----RIQ 55 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP 451 + + + I +II H N+N T NDI LI++ S+P Sbjct: 56 VRLGEHNIDVLEGNEQFI-NAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLP 114 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKE 507 C++SGWG K + + LQ + ++S+ C Y + Sbjct: 115 ------RSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQI-TGN 167 Query: 508 MECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFD 567 M C G +G D+C+GDSGGP+VC + G+VSWG C + PGVYTKV NY + Sbjct: 168 MICVGFLEGGKDSCQGDSGGPVVCNGQ-----LQGIVSWGYGCAQKNKPGVYTKVCNYVN 222 Query: 568 WISYHV 573 WI + Sbjct: 223 WIQQTI 228 >1EKB-B nrPDB Length = 235 Score = 254 bits (648), Expect = 9e-68, Method: Composition-based stats. Identities = 73/237 (30%), Positives = 114/237 (48%), Gaps = 10/237 (4%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASK--THRYQIWTTVV 397 IVGG ++ G PW VA+ CG + W+++AAHC+ +++ + Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 + +I +D+I+ + +YN NDIA++ ++ N D P C+P Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQ----PICLPEE 116 Query: 458 PYLFQPNDTCIVSGWG-REKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 +F P C ++GWG LQ +V L+SN C + + M CAG Sbjct: 117 NQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYE 176 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 G +D+C+GDSGGPL+C + NN + GV S+G C P PGVY +V + +WI Sbjct: 177 AGGVDSCQGDSGGPLMCQE-NNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQS 232 >3P8G-A nrPDB Length = 241 Score = 254 bits (648), Expect = 1e-67, Method: Composition-based stats. Identities = 77/245 (31%), Positives = 118/245 (48%), Gaps = 15/245 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKD-ASGITCGGIYIGGCWILTAAHC------LRASKTHRYQI 392 +VGG A G+ PWQV++ G CG I W+++AAHC R S ++ Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 393 WTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 + + D + + RII H +N T+ DIAL+E++K P Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVR----PI 116 Query: 453 CVPWSPYLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLISN--CSKFYGNRFYEKEME 509 C+P + ++F V+GWG + LQ GE+++I C + M Sbjct: 117 CLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQI-TPRMM 175 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 C G G +D+C+GDSGGPL ++A+ + GVVSWG+ C + PGVYT++ + DWI Sbjct: 176 CVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWI 235 Query: 570 SYHVG 574 + G Sbjct: 236 KENTG 240 >1F7Z-A nrPDB Length = 233 Score = 253 bits (646), Expect = 2e-67, Method: Composition-based stats. Identities = 73/247 (29%), Positives = 111/247 (44%), Gaps = 22/247 (8%) Query: 331 NRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRY 390 IVGG Q +P+QV++ ++ CGG I W+++AAHC ++ R Sbjct: 2 AFPVDDDDAIVGGYTCQENSVPYQVSL-NSGYHFCGGSLINDQWVVSAAHCYKS----RI 56 Query: 391 QIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSI 450 Q+ + + + +II H N++ T NDI LI++ ++ Sbjct: 57 QVRLGEHNINVLEGNEQFV-NAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVAL 115 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLIS--NCSKFYGNRFYEK 506 P+ C++SGWG + LQ + L+ +C Y + Sbjct: 116 PSSCA------PAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKI-TD 168 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 566 M C G +G D+C+GDSGGP+VC + G+VSWG C P+ PGVYTKV NY Sbjct: 169 NMVCVGFLEGGKDSCQGDSGGPVVCNGE-----LQGIVSWGYGCALPDNPGVYTKVCNYV 223 Query: 567 DWISYHV 573 DWI + Sbjct: 224 DWIQDTI 230 >5FXL-A nrPDB Length = 246 Score = 253 bits (646), Expect = 2e-67, Method: Composition-based stats. Identities = 73/247 (29%), Positives = 114/247 (46%), Gaps = 22/247 (8%) Query: 331 NRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRY 390 +IVGG +P+QV++ ++ CGG I W+++AAHC ++ Sbjct: 15 AFPVDDDDKIVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKSG----I 69 Query: 391 QIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSI 450 Q+ + + I + I H +YN+ T NDI LI++K + S+ Sbjct: 70 QVRLGEDNINVVEGNEQFIS-ASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISL 128 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEK 506 P + C++SGWG K + + L+ + ++S+ C Y + Sbjct: 129 PTSCASA------GTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQI-TS 181 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 566 M CAG +G D+C+GDSGGP+VC + G+VSWG C + PGVYTKV NY Sbjct: 182 NMFCAGYLEGGKDSCQGDSGGPVVCSGK-----LQGIVSWGSGCAQKNKPGVYTKVCNYV 236 Query: 567 DWISYHV 573 WI + Sbjct: 237 SWIKQTI 243 >6AOD-C nrPDB Length = 245 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 84/240 (35%), Positives = 118/240 (49%), Gaps = 11/240 (4%) Query: 340 IVGGKRAQLGDLPWQVAIKDAS---GITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 IVGG + G+ PWQV + S CGG IG WILTAAHC ++ + + Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + + V II H+ Y DIAL++++ D + P S+P+ Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 457 SPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 + C V+GWG K +++ +LQ ++ L++N C K Y +M CAG Sbjct: 121 NVIY----TDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGY 176 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 +G DACKGD+GGPL C N V ++ G+ SWGE C + E PGVYT V Y DWI Sbjct: 177 REGGKDACKGDAGGPLSCK-HNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKT 235 >4WWY-A nrPDB Length = 224 Score = 251 bits (642), Expect = 5e-67, Method: Composition-based stats. Identities = 72/238 (30%), Positives = 109/238 (45%), Gaps = 22/238 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + +P+QV++ ++ CGG I W+++A HC ++ R Q+ + Sbjct: 1 IVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKS----RIQVRLGEHNI 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + I +II H Y+ T NDI LI++ S+P P + Sbjct: 56 EVLEGNEQFI-NAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPPAT-- 112 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C++SGWG + + LQ + ++S C Y + M C G + Sbjct: 113 ----GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TSNMFCVGFLE 167 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 G D+C+ DSGGP+VC + GVVSWG+ C + PGVYTKV NY WI + Sbjct: 168 GGKDSCQRDSGGPVVCNGQ-----LQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 220 >5C67-A nrPDB Length = 224 Score = 250 bits (639), Expect = 9e-67, Method: Composition-based stats. Identities = 73/238 (30%), Positives = 106/238 (44%), Gaps = 22/238 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + LP+QV++ ++ CGG I W+++AAHC + R Q+ + Sbjct: 1 IVGGYTCEENSLPYQVSL-NSGSHFCGGSLISEQWVVSAAHCYKT----RIQVRLGEHNI 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + I +II H YN T NDI LI++ S+P P Sbjct: 56 KVLEGNEQFI-NAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP---- 110 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYD 515 C++SGWG + L+ + +++ C Y + M C G + Sbjct: 111 --AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKI-TNSMFCVGFLE 167 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 G D+C+ D+GGP+VC + GVVSWG C PGVYTKV NY DWI + Sbjct: 168 GGKDSCQRDAGGPVVCNGQ-----LQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI 220 >5UGG-A nrPDB Length = 251 Score = 250 bits (639), Expect = 1e-66, Method: Composition-based stats. Identities = 79/262 (30%), Positives = 122/262 (46%), Gaps = 18/262 (6%) Query: 320 SLLPKLSCGVKN-RMHIRRKRIVGGKRAQLGDLPWQVAIKDASG-ITCGGIYIGGCWILT 377 P CG R+VGG A PWQV+++ G CGG I W+LT Sbjct: 1 EFAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLT 60 Query: 378 AAHCL-RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMK 436 AAHCL ++ + Y++ ++ + IE V R+ + DIAL+++ Sbjct: 61 AAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIE-VSRLFLEPT------RKDIALLKLS 113 Query: 437 KDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN-- 494 D + IPAC+P Y+ C ++GWG + L+ ++ +I N Sbjct: 114 SPAVITD----KVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKV 169 Query: 495 CSKF-YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKP 553 C+++ + N + CAG G D+C+GDSGGPLVC + + + GV SWG C +P Sbjct: 170 CNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDK-YILQGVTSWGLGCARP 228 Query: 554 EFPGVYTKVANYFDWISYHVGR 575 PGVY +V+ + WI + Sbjct: 229 NKPGVYVRVSRFVTWIEGVMRN 250 >1YC0-A nrPDB Length = 283 Score = 249 bits (637), Expect = 2e-66, Method: Composition-based stats. Identities = 80/260 (30%), Positives = 124/260 (47%), Gaps = 9/260 (3%) Query: 324 KLSCGVKNR-MHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL 382 + +CG +++ R RI+GG + G PW AI C G + CW+++AAHC Sbjct: 19 RQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCF 77 Query: 383 RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGT-YQNDIALIEMKKDGNK 441 S + + +++ I + Y+ +D+ LI +KK G++ Sbjct: 78 SHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDR 137 Query: 442 KDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLISNCSKFY 499 P C+P F C ++GWG +N SL+ V L+++ Sbjct: 138 CATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSS 197 Query: 500 GNRF---YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFP 556 + M CAG +D DAC+GDSGGPL C + N V Y++G++SWG+ CG+ P Sbjct: 198 PEVYGADISPNMLCAGYFDCKSDACQGDSGGPLAC-EKNGVAYLYGIISWGDGCGRLHKP 256 Query: 557 GVYTKVANYFDWISYHVGRP 576 GVYT+VANY DWI+ + P Sbjct: 257 GVYTRVANYVDWINDRIRPP 276 >1A0J-A nrPDB Length = 223 Score = 249 bits (637), Expect = 2e-66, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 116/238 (48%), Gaps = 22/238 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + +Q +++ CGG I W+++AAHC ++ R Q+ + Sbjct: 1 IVGGYECRKNSASYQASLQSGY-HFCGGSLISSTWVVSAAHCYKS----RIQVRLGEHNI 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + I+ V ++I H +YN+ NDI LI++ K + ++P+ S Sbjct: 56 AVNEGTEQFIDSV-KVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASS-- 112 Query: 460 LFQPNDTCIVSGWGREK--DNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C+VSGWG + +L+ ++ ++S+ C+ Y + M CAG + Sbjct: 113 ----GTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQI-TSNMFCAGFME 167 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 G D+C+GDSGGP+VC + GVVSWG C + PGVYTKV NY WIS + Sbjct: 168 GGKDSCQGDSGGPVVCNGQ-----LQGVVSWGYGCAQRNKPGVYTKVCNYRSWISSTM 220 >1FXY-A nrPDB Length = 228 Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats. Identities = 75/239 (31%), Positives = 114/239 (47%), Gaps = 20/239 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDA-SGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IVGG + G++PWQ + + + CGG + +ILTAAHCL +K + ++ Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN-- 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + V+ +I H + TY DIA++ +K + P S+P P + Sbjct: 59 -TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPAT- 116 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 C++SGWG + + LQ + ++S C Y + M C G Sbjct: 117 -----GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI-TSNMFCVGFL 170 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 +G D+C+GDSGGP+VC + GVVSWG+ C + PGVYTKV NY WI + Sbjct: 171 EGGKDSCQGDSGGPVVCNGQ-----LQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTI 224 >3T2N-A nrPDB Length = 372 Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats. Identities = 90/266 (33%), Positives = 133/266 (50%), Gaps = 27/266 (10%) Query: 325 LSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL-- 382 CG R + RIVGG+ LG PWQV+++ CGG + G W+LTAAHC Sbjct: 106 QDCG---RRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPE 162 Query: 383 RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENY------NAGTYQNDIALIEMK 436 R R++++ V P ++ V +++H Y N+ NDIAL+ + Sbjct: 163 RNRVLSRWRVFAGAVAQASPHGLQL---GVQAVVYHGGYLPFRDPNSEENSNDIALVHLS 219 Query: 437 KDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLISN- 494 + P C+P + C V+GWG + ++ LQ V +ISN Sbjct: 220 SPLPLTEYIQ----PVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISND 275 Query: 495 -CS--KFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANN---VTYVWGVVSWGE 548 C+ FYGN+ + +M CAG +G IDAC+GDSGGP VC D+ + + G+VSWG Sbjct: 276 VCNGADFYGNQI-KPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT 334 Query: 549 NCGKPEFPGVYTKVANYFDWISYHVG 574 C + PGVYTKV+++ +WI + Sbjct: 335 GCALAQKPGVYTKVSDFREWIFQAIK 360 >4MPW-A nrPDB Length = 245 Score = 248 bits (634), Expect = 4e-66, Method: Composition-based stats. Identities = 83/253 (32%), Positives = 116/253 (45%), Gaps = 25/253 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG---ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 IVGG+ A PWQV+++ CGG I W+LTAAHC+ + V Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR--V 58 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + + V RII H + DIAL+E+++ ++P Sbjct: 59 QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLP----P 114 Query: 457 SPYLFQPNDTCIVSGWGREKDNER---VFSLQWGEVKLISN--CSKFYG--------NRF 503 + F P C V+GWG ++ER F L+ +V ++ N C Y R Sbjct: 115 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 174 Query: 504 YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVA 563 +M CAG D+C+GDSGGPLVC N GVVSWGE C +P PG+YT+V Sbjct: 175 VRDDMLCAGNTR--RDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 231 Query: 564 NYFDWISYHVGRP 576 Y DWI ++V + Sbjct: 232 YYLDWIHHYVPKK 244 >3LC3-A nrPDB Length = 235 Score = 248 bits (634), Expect = 4e-66, Method: Composition-based stats. Identities = 78/241 (32%), Positives = 111/241 (46%), Gaps = 14/241 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 +VGG+ A+ G PWQV + CGG + WI+TAAHC+ + + + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETG--VKITVVAGEHN- 57 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGT--YQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 I V RII H NYNA Y +DIAL+E+ + P C+ Sbjct: 58 IEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYV----TPICIADK 113 Query: 458 PYL--FQPNDTCIVSGWGRE-KDNERVFSLQWGEVKLISNCSKFYGNRF-YEKEMECAGT 513 Y F + VSGWGR LQ+ V L+ + +F M CAG Sbjct: 114 EYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGF 173 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 ++G D+C+GDSGGP V + +++ G++SWGE C G+YTKV+ Y +WI Sbjct: 174 HEGGRDSCQGDSGGPHVT-EVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKT 232 Query: 574 G 574 Sbjct: 233 K 233 >3DFJ-A nrPDB Length = 263 Score = 248 bits (633), Expect = 5e-66, Method: Composition-based stats. Identities = 82/247 (33%), Positives = 113/247 (45%), Gaps = 19/247 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS-KTHRYQIWTTVVD 398 I GG A G PWQV+I CGG + W+L+AAHC + Y++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + + II H +Y Q DIAL+++ + P S+PA + Sbjct: 61 LDSYS-EDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPA----AN 115 Query: 459 YLFQPNDTCIVSGWGREKDN---ERVFSLQWGEVKLISN--CSKFYG-------NRFYEK 506 F C V+GWG + LQ EV LIS C+ Y F ++ Sbjct: 116 ASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQE 175 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 566 +M CAG +G DAC+GDSGGPL C + Y+ G+VSWG+ CG PGVYT ++Y Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCP-VEGLWYLTGIVSWGDACGARNRPGVYTLASSYA 234 Query: 567 DWISYHV 573 WI V Sbjct: 235 SWIQSKV 241 >4KKD-A nrPDB Length = 433 Score = 248 bits (632), Expect = 7e-66, Method: Composition-based stats. Identities = 88/299 (29%), Positives = 131/299 (43%), Gaps = 45/299 (15%) Query: 316 RRIKSLLPKLSCGVKNRM-HIRRKRIVGGKRAQLGDLPWQVAIK-------DASGITCGG 367 R + + LP+ CG +R +RI+GG+ A+ G PWQ I G Sbjct: 132 RSLPTCLPE--CGQPSRSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSG 189 Query: 368 IYIGGCWILTAAHCLRASKTHR---------YQIWTTVVDWIHPDLKRIVIEYVDRIIFH 418 + WILTAAH LR+ + ++ + D D V R++ H Sbjct: 190 ALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDV--RDKSGAVNSSAARVVLH 247 Query: 419 ENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN 478 ++N Y +DIAL+++++ +P +P P P P+ +V+GWG N Sbjct: 248 PDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGP---APHMLGLVAGWGISNPN 304 Query: 479 ------------ERVFSLQWGEVKLISN--CSKFY----GNRFYEKEMECAGTYDGSIDA 520 LQ+ ++ ++ + C Y GN + M CAG Y+G D Sbjct: 305 VTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDT 364 Query: 521 CKGDSGGPLV-CMDANNVTYVWGVVSWG--ENCGKPEFPGVYTKVANYFDWISYHVGRP 576 C GDSG V D + V G+VSWG E CG + GVYTKV+NY DW+ +G P Sbjct: 365 CLGDSGEAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLP 423 >3E0N-B nrPDB Length = 271 Score = 246 bits (629), Expect = 1e-65, Method: Composition-based stats. Identities = 82/247 (33%), Positives = 112/247 (45%), Gaps = 19/247 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS-KTHRYQIWTTVVD 398 I GG A G PWQV+I CGG + W+L+AAHC + Y++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + + II H +Y Q DIAL+++ + P S+PA Sbjct: 61 LDSYS-EDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQAS-- 117 Query: 459 YLFQPNDTCIVSGWGREKDN---ERVFSLQWGEVKLISN--CSKFYG-------NRFYEK 506 F C V+GWG + LQ EV LIS C+ Y F ++ Sbjct: 118 --FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQE 175 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 566 +M CAG +G DAC+GDSGGPL C + Y+ G+VSWG+ CG PGVYT ++Y Sbjct: 176 DMVCAGYVEGGKDACQGDSGGPLSCP-VEGLWYLTGIVSWGDACGARNRPGVYTLASSYA 234 Query: 567 DWISYHV 573 WI V Sbjct: 235 SWIQSKV 241 >1X7A-C nrPDB Length = 235 Score = 246 bits (629), Expect = 2e-65, Method: Composition-based stats. Identities = 79/241 (32%), Positives = 114/241 (47%), Gaps = 14/241 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG+ A+ G PWQV + CGG I W++TAAHC+ + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNA--GTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 P +R V R I H +YNA Y +DIAL+E+ + P C+ Sbjct: 61 TEPTEQR---RNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYV----TPICIADK 113 Query: 458 PYL--FQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRF-YEKEMECAGT 513 Y F + VSGWGR + R + LQ+ +V L+ + +F M CAG Sbjct: 114 EYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGF 173 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 ++G D+C+GDSGGP V + +++ G++SWGE C G+YTKV+ Y +WI Sbjct: 174 HEGGKDSCQGDSGGPHVT-EVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNWIKEKT 232 Query: 574 G 574 Sbjct: 233 K 233 >2F91-A nrPDB Length = 237 Score = 246 bits (628), Expect = 2e-65, Method: Composition-based stats. Identities = 79/243 (32%), Positives = 115/243 (47%), Gaps = 18/243 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDA----SGITCGGIYIGGCWILTAAHCLRASKTHR---YQI 392 IVGG A LG+ P+Q++ ++ S CG + +TA HC+ QI Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 393 WTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA 452 +D + +I V +II HEN++ NDI+L+++ D P ++P Sbjct: 61 VAGELDMSVNEGSEQII-TVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALP- 118 Query: 453 CVPWSPYLFQPNDTCIVSGWGREKDNE-RVFSLQWGEVKLISN--CSKFYGNRFYEKEME 509 IV+GWG + LQ V L+S+ C YG M Sbjct: 119 -----EQGHTATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMI 173 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 CAG +G D+C+GDSGGPL D TY+ G+VSWG C +P +PGVYT+V+ + DWI Sbjct: 174 CAGVPEGGKDSCQGDSGGPLAASDT-GSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWI 232 Query: 570 SYH 572 + Sbjct: 233 KAN 235 >3K65-B nrPDB Length = 308 Score = 245 bits (626), Expect = 3e-65, Method: Composition-based stats. Identities = 76/260 (29%), Positives = 104/260 (40%), Gaps = 24/260 (9%) Query: 338 KRIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASK------THR 389 RIV G A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 48 GRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 107 Query: 390 YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPR 448 + + I +++I H YN DIAL+++KK D P Sbjct: 108 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 167 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISN--CSKFY 499 +P + L Q V+GWG K+ + LQ + ++ C Sbjct: 168 CLPD-RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 226 Query: 500 GNRFYEKEMECAGT---YDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEF 555 R M CAG DAC+GD+GGP V NN Y G+VSWGE C + Sbjct: 227 RIRI-TDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 285 Query: 556 PGVYTKVANYFDWISYHVGR 575 G YT V WI + + Sbjct: 286 YGFYTHVFRLKKWIQKVIDQ 305 >2OQ5-A nrPDB Length = 232 Score = 245 bits (626), Expect = 4e-65, Method: Composition-based stats. Identities = 85/240 (35%), Positives = 120/240 (50%), Gaps = 14/240 (5%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + G+ PWQ +++ CG I W+++AAHC K + V Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 +KR + RII HE Y ++ DI+L E+ + C+P + Y Sbjct: 61 KPSKMKR----GLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRV----CLPDASY 112 Query: 460 LFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLIS----NCSKFYGNRFYEKEMECAGTY 514 FQP D V+G+G K++ L+ +V LI N + Y N M CAG+ Sbjct: 113 EFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY-NDAITPRMLCAGSL 171 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 +G DAC+GDSGGPLV DA ++ Y+ G+VSWG+ C KP PGVYT+V DWI+ G Sbjct: 172 EGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTG 231 >1PYT-D nrPDB Length = 251 Score = 245 bits (625), Expect = 4e-65, Method: Composition-based stats. Identities = 86/257 (33%), Positives = 124/257 (48%), Gaps = 18/257 (7%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCL 382 CG R+VGG+ A PWQ++++ + TCGG I +LTAAHC+ Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 383 RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKK 442 S T Y++ + D + VD I HE +N+ +NDIALI++ + Sbjct: 61 --SNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELG 118 Query: 443 DCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLIS--NCSKF- 498 D AC+P L + C V+GWGR N + LQ G ++ CS+ Sbjct: 119 DTIQV----ACLPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRD 174 Query: 499 YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN--CGKPEFP 556 + ++ M CAG DG I AC GDSGGPL C A+ V G+VS+G C + P Sbjct: 175 WWGTTVKETMVCAGG-DGVISACNGDSGGPLNCQ-ADGQWDVRGIVSFGSGLSCNTFKKP 232 Query: 557 GVYTKVANYFDWISYHV 573 V+T+V+ Y DWI+ + Sbjct: 233 TVFTRVSAYIDWINQKL 249 >1MKW-K nrPDB Length = 308 Score = 243 bits (621), Expect = 1e-64, Method: Composition-based stats. Identities = 79/260 (30%), Positives = 106/260 (40%), Gaps = 24/260 (9%) Query: 338 KRIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHR------ 389 RIV G+ A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 48 GRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDD 107 Query: 390 YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPR 448 + + K I +D+I H YN DIAL+++K+ D P Sbjct: 108 LLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPV 167 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISN--CSKFY 499 +P + L V+GWG ++ + LQ + L+ C Sbjct: 168 CLPDK-QTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAST 226 Query: 500 GNRFYEKEMECAGTYDGSI---DACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEF 555 R M CAG G DAC+GDSGGP V NN Y G+VSWGE C + Sbjct: 227 RIRI-TDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGK 285 Query: 556 PGVYTKVANYFDWISYHVGR 575 G YT V WI + R Sbjct: 286 YGFYTHVFRLKKWIQKVIDR 305 >1LTO-A nrPDB Length = 245 Score = 243 bits (620), Expect = 2e-64, Method: Composition-based stats. Identities = 84/255 (32%), Positives = 115/255 (45%), Gaps = 29/255 (11%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG---ITCGGIYIGGCWILTAAHCLRASKTH--RYQIWT 394 IVGG+ A PWQV+++ CGG I W+LTAAHCL ++ Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 454 + D + V RII H + DIAL+E+++ N +P Sbjct: 61 REQHLYYQD----QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLP--- 113 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNER---VFSLQWGEVKLISN--CSKFYG--------N 501 + F P C V+GWG ++E F L+ +V ++ N C Y Sbjct: 114 -PASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 172 Query: 502 RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTK 561 R +M CAG D+CKGDSGGPLVC N GVVSW E C +P PG+YT+ Sbjct: 173 RIIRDDMLCAGNS--QRDSCKGDSGGPLVCK-VNGTWLQAGVVSWDEGCAQPNRPGIYTR 229 Query: 562 VANYFDWISYHVGRP 576 V Y DWI ++V + Sbjct: 230 VTYYLDWIHHYVPKK 244 >4H4F-A nrPDB Length = 249 Score = 242 bits (618), Expect = 3e-64, Method: Composition-based stats. Identities = 84/244 (34%), Positives = 125/244 (51%), Gaps = 17/244 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKD----ASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG+ A+ PWQ++++ TCGG I ++LTAAHC+ ++T Y++ Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRT--YRVAVG 58 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + D + + VD I H+ +NA +NDIALI++ + D AC+P Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQV----ACLP 114 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISN--CSKF-YGNRFYEKEMECA 511 L + C V+GWGR N + LQ G ++ + CS+ + +K M CA Sbjct: 115 EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA 174 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE--NCGKPEFPGVYTKVANYFDWI 569 G DG I AC GDSGGPL C N V+G+VS+G C + P VYT+V+ Y DWI Sbjct: 175 GG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 233 Query: 570 SYHV 573 + + Sbjct: 234 NEKM 237 >4NFE-A nrPDB Length = 237 Score = 242 bits (618), Expect = 3e-64, Method: Composition-based stats. Identities = 82/250 (32%), Positives = 109/250 (43%), Gaps = 33/250 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + PWQVA+ CGG+ + W+LTAAHCL+ Q+W + Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKK----NSQVWLGRHNL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTY-----------QNDIALIEMKKDGNKKDCELPR 448 P+ + V H YN +D+ L+ + + D Sbjct: 57 FEPEDTGQRV-PVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL 115 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLISN--CSKFYGNRFY 504 +P P TC SGWG + E R SLQ + L+SN C++ Y + Sbjct: 116 GLPTQEPAL------GTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVT 169 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVA 563 E M CAG + G D C GDSGGPLVC + G+ SWG E C PE P VYTKV Sbjct: 170 EF-MLCAGLWTGGKDTCGGDSGGPLVCNGV-----LQGITSWGPEPCALPEKPAVYTKVV 223 Query: 564 NYFDWISYHV 573 +Y WI + Sbjct: 224 HYRKWIKDTI 233 >1FIW-A nrPDB Length = 290 Score = 242 bits (617), Expect = 4e-64, Method: Composition-based stats. Identities = 90/257 (35%), Positives = 128/257 (49%), Gaps = 22/257 (8%) Query: 340 IVGGKRAQLGDLPWQVAIK------DASGITCGGIYIGGCWILTAAHCLRASKT---HRY 390 I+GG+ A G PW V+++ + CGG + W+LTAAHC R K R Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 391 QIWTTVVDWIHPDLKRIVIE--YVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPR 448 V+W + ++ YV++II HE Y+A + NDIAL+++ P Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS----NCSKFYGNR 502 +P P + Q TC V+GWG ++N R S LQ V LI N +++Y R Sbjct: 121 CLPQFRAGPPRVPQ---TCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGR 177 Query: 503 FYEKEMECAGTYDGSIDACKGDSGGPLVCMD-ANNVTYVWGVVSWGENCGKPEFPGVYTK 561 CAG +G ID C+GDSGGPL+C D A N V G+ SWG C + + PGVYT Sbjct: 178 IRSTN-VCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVGCARAKRPGVYTS 236 Query: 562 VANYFDWISYHVGRPFI 578 +Y +WI+ +G + Sbjct: 237 TWSYLNWIASKIGSTAV 253 >3NXP-A nrPDB Length = 424 Score = 241 bits (616), Expect = 4e-64, Method: Composition-based stats. Identities = 77/260 (29%), Positives = 104/260 (40%), Gaps = 24/260 (9%) Query: 338 KRIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASK------THR 389 RIV G A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 164 GRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 223 Query: 390 YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPR 448 + + I +++I H YN DIAL+++KK D P Sbjct: 224 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 283 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISN--CSKFY 499 +P + L Q V+GWG K+ + LQ + ++ C Sbjct: 284 CLPD-RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 342 Query: 500 GNRFYEKEMECAGT---YDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEF 555 R M CAG DAC+GDSGGP V NN Y G+VSWGE C + Sbjct: 343 RIRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 401 Query: 556 PGVYTKVANYFDWISYHVGR 575 G YT V WI + + Sbjct: 402 YGFYTHVFRLKKWIQKVIDQ 421 >1BDA-A nrPDB Length = 265 Score = 241 bits (616), Expect = 4e-64, Method: Composition-based stats. Identities = 90/267 (33%), Positives = 131/267 (49%), Gaps = 21/267 (7%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASG------ITCGGIYIGGCWILTAAH 380 CG++ + RI GG A + PWQ AI CGGI I CWIL+AAH Sbjct: 2 CGLRQYSQPQF-RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAH 60 Query: 381 CLRAS-KTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDG 439 C + H + + P + E V++ I H+ ++ TY NDIAL+++K D Sbjct: 61 CFQERFPPHHLTVILGRTYRVVPGEEEQKFE-VEKYIVHKEFDDDTYDNDIALLQLKSDS 119 Query: 440 NKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLI--SNC 495 ++ E C+P + C +SG+G+ + +S L+ V+L S C Sbjct: 120 SRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRC 179 Query: 496 SKFY-GNRFYEKEMECAGTYDGSI------DACKGDSGGPLVCMDANNVTYVWGVVSWGE 548 + + NR M CAG DAC+GDSGGPLVC++ +T + G++SWG Sbjct: 180 TSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMT-LVGIISWGL 238 Query: 549 NCGKPEFPGVYTKVANYFDWISYHVGR 575 CG+ + PGVYTKV NY DWI ++ Sbjct: 239 GCGQKDVPGVYTKVTNYLDWIRDNMRP 265 >1P57-B nrPDB Length = 255 Score = 241 bits (615), Expect = 7e-64, Method: Composition-based stats. Identities = 86/251 (34%), Positives = 128/251 (50%), Gaps = 24/251 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASKTHRYQIWTTVV 397 IVGG+ LG PWQV+++ CGG + G W+LTAAHC R R++++ V Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENY------NAGTYQNDIALIEMKKDGNKKDCELPRSIP 451 P ++ V +++H Y N+ NDIAL+ + + P Sbjct: 61 AQASPHGLQL---GVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQ----P 113 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKLISN--CS--KFYGNRFYEK 506 C+P + C V+GWG + ++ LQ V +ISN C+ FYGN+ + Sbjct: 114 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQI-KP 172 Query: 507 EMECAGTYDGSIDACKGDSGGPLVCMDANN---VTYVWGVVSWGENCGKPEFPGVYTKVA 563 +M CAG +G IDAC+GDSGGP VC D+ + + G+VSWG C + PGVYTKV+ Sbjct: 173 KMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVS 232 Query: 564 NYFDWISYHVG 574 ++ +WI + Sbjct: 233 DFREWIFQAIK 243 >2CGA-A nrPDB Length = 245 Score = 241 bits (614), Expect = 7e-64, Method: Composition-based stats. Identities = 77/254 (30%), Positives = 117/254 (46%), Gaps = 19/254 (7%) Query: 327 CGVKNRMHIRRK--RIVGGKRAQLGDLPWQVAIKDASG-ITCGGIYIGGCWILTAAHCLR 383 CGV + RIV G+ A G PWQV+++D +G CGG I W++TAAHC Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC-- 58 Query: 384 ASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKD 443 T + D ++I + ++ + YN+ T NDI L+++ + Sbjct: 59 -GVTTSDVVVAGEFDQGSSS-EKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQ 116 Query: 444 CELPRSIPACVPWSPYLFQPNDTCIVSGWGRE--KDNERVFSLQWGEVKLISN--CSKFY 499 C+P + F TC+ +GWG + LQ + L+SN C K++ Sbjct: 117 TVSAV----CLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYW 172 Query: 500 GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVY 559 G + + M CAG + +C GDSGGPLVC N + G+VSWG + PGVY Sbjct: 173 GTKI-KDAMICAGAS--GVSSCMGDSGGPLVCKK-NGAWTLVGIVSWGSSTCSTSTPGVY 228 Query: 560 TKVANYFDWISYHV 573 +V +W+ + Sbjct: 229 ARVTALVNWVQQTL 242 >1SGF-G nrPDB Length = 237 Score = 240 bits (613), Expect = 1e-63, Method: Composition-based stats. Identities = 78/252 (30%), Positives = 114/252 (45%), Gaps = 33/252 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + + PW VA+ + CGG+ + W+LTAAHC Y++W + Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYD----DNYKVWLGKNNL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAG-----------TYQNDIALIEMKKDGNKKDCELPR 448 D +V + I H +N Y ND+ L+ + K + D P Sbjct: 57 FK-DEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPI 115 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLISN--CSKFYGNRFY 504 ++P P + TC+ SGWG + L +KL+ N C+K + + Sbjct: 116 TLPTEEP------KLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKV- 168 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVA 563 M CAG DG D CKGDSGGPL+C + G+ SWG CG+P+ PGVYTK+ Sbjct: 169 TDAMLCAGEMDGGKDTCKGDSGGPLICDGV-----LQGITSWGHTPCGEPDMPGVYTKLN 223 Query: 564 NYFDWISYHVGR 575 + WI + + Sbjct: 224 KFTSWIKDTMAK 235 >4DUR-A nrPDB Length = 791 Score = 239 bits (611), Expect = 2e-63, Method: Composition-based stats. Identities = 79/265 (29%), Positives = 123/265 (46%), Gaps = 19/265 (7%) Query: 318 IKSLL-PKLSCGVKN-RMHIRRKRIVGGKRAQLGDLPWQVAIKDASG-ITCGGIYIGGCW 374 + P CG R+VGG A PWQV+++ G CGG I W Sbjct: 538 VPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEW 597 Query: 375 ILTAAHCL-RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALI 433 +LTAAHCL ++ + Y++ ++ + IE V R+ + DIAL+ Sbjct: 598 VLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIE-VSRLFLEPT------RKDIALL 650 Query: 434 EMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLIS 493 ++ D + IPAC+P Y+ C ++GWG + L+ ++ +I Sbjct: 651 KLSSPAVITD----KVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIE 706 Query: 494 N--CSKF-YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENC 550 N C+++ + N + CAG G D+C+GDSGGPLVC + + + GV SWG C Sbjct: 707 NKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDK-YILQGVTSWGLGC 765 Query: 551 GKPEFPGVYTKVANYFDWISYHVGR 575 +P PGVY +V+ + WI + Sbjct: 766 ARPNKPGVYVRVSRFVTWIEGVMRN 790 >1ETT-H nrPDB Length = 259 Score = 239 bits (611), Expect = 2e-63, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 105/258 (40%), Gaps = 24/258 (9%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHR------YQ 391 IV G+ A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSI 450 + + K I +D+I H YN DIAL+++K+ D P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISN--CSKFYGN 501 P + L V+GWG ++ + LQ + L+ C Sbjct: 121 PDK-QTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRI 179 Query: 502 RFYEKEMECAGTYDGSI---DACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEFPG 557 R M CAG G DAC+GDSGGP V NN Y G+VSWGE C + G Sbjct: 180 RI-TDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYG 238 Query: 558 VYTKVANYFDWISYHVGR 575 YT V WI + R Sbjct: 239 FYTHVFRLKKWIQKVIDR 256 >1ELV-A nrPDB Length = 333 Score = 239 bits (610), Expect = 3e-63, Method: Composition-based stats. Identities = 77/275 (28%), Positives = 119/275 (43%), Gaps = 32/275 (11%) Query: 318 IKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILT 377 + +P CGV ++RI+GG A + + PWQV + GG I W+LT Sbjct: 63 LPKCVP--VCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLT 117 Query: 378 AAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-------AGTYQNDI 430 AAH + ++ + +T V L + + + + H + + NDI Sbjct: 118 AAHVVEGNREPTMYVGSTSVQT--SRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDI 175 Query: 431 ALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVK 490 AL+ +K P +P S Y D ++SGWGR + +R L+ + Sbjct: 176 ALVRLKDPVKMGPTVSPICLPGT--SSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLP 233 Query: 491 L--ISNCSKFYGNR--------FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVT-- 538 + + C + + + M CAG + +D+CKGDSGG D N+ T Sbjct: 234 VAPLRKCKEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKF 292 Query: 539 YVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 Y G+VSWG CG G+YT+V NY DWI + Sbjct: 293 YAAGLVSWGPQCGT---YGLYTRVKNYVDWIMKTM 324 >1FIZ-A nrPDB Length = 263 Score = 238 bits (608), Expect = 4e-63, Method: Composition-based stats. Identities = 86/253 (33%), Positives = 120/253 (47%), Gaps = 22/253 (8%) Query: 340 IVGGKRAQLGDLPWQVAIK------DASGITCGGIYIGGCWILTAAHCLRASKT---HRY 390 +VGG A+ G PW V+++ + TCGGI + W+LTAAHC + K R Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 391 QIWTTVVDWIHPDLKRIVIE--YVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPR 448 V W + ++ +V+ II HE Y +G NDIALI++ P Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDNER--VFSLQWGEVKLIS----NCSKFYGNR 502 +P + + TC V+GWG K+ +LQ V LI N +++Y R Sbjct: 121 CLP---QFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGR 177 Query: 503 FYEKEMECAGTYDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEFPGVYTK 561 CAG G ID C+GDSGGPL+C D N V G+ SWG C + + PGVYT Sbjct: 178 IRSTN-VCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTS 236 Query: 562 VANYFDWISYHVG 574 Y +WI+ +G Sbjct: 237 TWPYLNWIASKIG 249 >2OCV-B nrPDB Length = 259 Score = 238 bits (608), Expect = 4e-63, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 101/258 (39%), Gaps = 24/258 (9%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASK------THRYQ 391 IV G A+ G PWQV + K + CG I W+LTAAHC+ + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSI 450 + + I +++I H YN DIAL+++KK D P + Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISN--CSKFYGN 501 P L + V+GWG ++ + LQ + ++ C Sbjct: 121 PDK-QTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRI 179 Query: 502 RFYEKEMECAGT---YDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEFPG 557 R M CAG DAC+GDSGGP V NN Y G+VSWGE C + G Sbjct: 180 RI-TDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYG 238 Query: 558 VYTKVANYFDWISYHVGR 575 YT V WI + + Sbjct: 239 FYTHVFRLKAWIQKVIDQ 256 >1VR1-H nrPDB Length = 261 Score = 238 bits (608), Expect = 4e-63, Method: Composition-based stats. Identities = 74/262 (28%), Positives = 100/262 (38%), Gaps = 28/262 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG------ITCGGIYIGGCWILTAAHCLRASK------T 387 IV G A++G PWQV + CG I W+LTAAHCL Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 388 HRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCEL 446 + + + I +++I H YN DIAL+++KK D Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 447 PRSIPACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISN--CSK 497 P +P + L Q V+GWG K+ + LQ + ++ C Sbjct: 121 PVCLPD-RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKD 179 Query: 498 FYGNRFYEKEMECA---GTYDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKP 553 R M CA DAC+GDSGGP V NN Y G+VSWGE C + Sbjct: 180 STRIRI-TDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRD 238 Query: 554 EFPGVYTKVANYFDWISYHVGR 575 G YT V WI + + Sbjct: 239 GKYGFYTHVFRLKKWIQKVIDQ 260 >1BRU-P nrPDB Length = 241 Score = 238 bits (606), Expect = 7e-63, Method: Composition-based stats. Identities = 82/246 (33%), Positives = 127/246 (51%), Gaps = 20/246 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDAS----GITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG+ A+ PWQV+++ S TCGG + W+LTAAHC+ +S+T+R + Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTY--QNDIALIEMKKDGNKKDCELPRSIPAC 453 + P + V +++ H+++N+ NDIAL+++ + D C Sbjct: 61 SLSTNEPGSLAV---KVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQL----GC 113 Query: 454 VPWSPYLFQPNDTCIVSGWGREKDNE-RVFSLQWGEVKLIS--NCSK-FYGNRFYEKEME 509 +P + + N C V+GWGR + N LQ G++ ++ CSK + + M Sbjct: 114 LPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMI 173 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE--NCGKPEFPGVYTKVANYFD 567 CAG DG I +C GDSGGPL C AN V G+VS+G C P V+T+V+NY D Sbjct: 174 CAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYID 232 Query: 568 WISYHV 573 WI+ + Sbjct: 233 WINSVI 238 >4IGD-A nrPDB Length = 406 Score = 238 bits (606), Expect = 7e-63, Method: Composition-based stats. Identities = 82/279 (29%), Positives = 124/279 (44%), Gaps = 29/279 (10%) Query: 316 RRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGI-TCGGIYIGGCW 374 R + + LP CG+ +I G+ AQ G PW + +G CGG +G W Sbjct: 134 RSLPTCLP--VCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSW 191 Query: 375 ILTAAHCLRASK--------------THRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHEN 420 I+TAAHCL S ++I + D V H Sbjct: 192 IVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENE-QHLGVKHTTLHPQ 250 Query: 421 YNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNER 480 Y+ T++ND+AL+E+ + +P +P Q IVSGWG++ Sbjct: 251 YDPNTFENDVALVELLESPVLNAFVMPICLP------EGPQQEGAMVIVSGWGKQFLQRF 304 Query: 481 VFSLQWGEVKLISN--CSKFYGN--RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDA-N 535 +L E+ ++ + C K Y + ++M CAG +G DAC GDSGGP+V ++ Sbjct: 305 PETLMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRER 364 Query: 536 NVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 Y+ G VSWG++CGK + GVY+ + + DWI G Sbjct: 365 GQWYLVGTVSWGDDCGKKDRYGVYSYIHHNKDWIQRVTG 403 >1C5M-D nrPDB Length = 255 Score = 237 bits (605), Expect = 1e-62, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 112/238 (47%), Gaps = 8/238 (3%) Query: 340 IVGGKRAQLGDLPWQVAIKDA-SGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IVGG+ + G+ PWQ + + + CGG + +ILTAAHCL +K + ++ Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRN-- 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + V+ +I H + TY DIA++ +K + P +P W+ Sbjct: 59 -TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPE-RDWAE 116 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLIS-NCSKFYGNRFYEKEMECAGTYDG 516 T IVSG+GR + R + L+ EV + N K + + M CAG Sbjct: 117 STLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTK 176 Query: 517 SIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 DAC+GDSGGP V + +V G+VSWGE C + G+YTKV + WI + Sbjct: 177 QEDACQGDSGGPHVTR-FKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMK 233 >2R0L-A nrPDB Length = 248 Score = 236 bits (603), Expect = 2e-62, Method: Composition-based stats. Identities = 76/243 (31%), Positives = 115/243 (47%), Gaps = 8/243 (3%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG + G PW AI C G + CW+++AAHC S + Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGT-YQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + +++ I + Y+ +D+ LI +KK G++ P C+P Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 119 Query: 459 YLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLISNCSKFYGNRF---YEKEMECAGT 513 F C ++GWG +N SL+ V L+++ + M CAG Sbjct: 120 STFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGY 179 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 +D DAC+GDSGGPL C + N V Y++G++SWG+ CG+ PGVYT+VANY DWI+ + Sbjct: 180 FDCKSDACQGDSGGPLAC-EKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRI 238 Query: 574 GRP 576 P Sbjct: 239 RPP 241 >4NZQ-A nrPDB Length = 557 Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats. Identities = 77/260 (29%), Positives = 104/260 (40%), Gaps = 24/260 (9%) Query: 338 KRIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASK------THR 389 RIV G A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 297 GRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 356 Query: 390 YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPR 448 + + I +++I H YN DIAL+++KK D P Sbjct: 357 LLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPV 416 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISN--CSKFY 499 +P + L Q V+GWG K+ + LQ + ++ C Sbjct: 417 CLPD-RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 475 Query: 500 GNRFYEKEMECAGT---YDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEF 555 R M CAG DAC+GDSGGP V NN Y G+VSWGE C + Sbjct: 476 RIRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK 534 Query: 556 PGVYTKVANYFDWISYHVGR 575 G YT V WI + + Sbjct: 535 YGFYTHVFRLKKWIQKVIDQ 554 >4Z6A-H nrPDB Length = 249 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 76/238 (31%), Positives = 105/238 (44%), Gaps = 6/238 (2%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGGK G+ PWQV + CGG I W+++AAHC K R I Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + V ++I Y GT +DIAL+ + + D +P +P +S Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERT-FSER 119 Query: 460 LFQPNDTCIVSGWGREKDNE-RVFSLQWGEVK--LISNCSKFYGNRFYEKEMECAGTYDG 516 +VSGWG+ D L V + +C Y + E M CAG DG Sbjct: 120 TLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEY-MFCAGYSDG 178 Query: 517 SIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 S D+CKGDSGGP Y+ G+VSWG+ C GVYT+V+ Y +W+ + Sbjct: 179 SKDSCKGDSGGPHATH-YRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMR 235 >4IW4-E nrPDB Length = 279 Score = 236 bits (601), Expect = 3e-62, Method: Composition-based stats. Identities = 82/274 (29%), Positives = 120/274 (43%), Gaps = 42/274 (15%) Query: 340 IVGGKRAQLGDLPWQVAIK-------DASGITCGGIYIGGCWILTAAHCLRASKTHR--- 389 I+GG+ A+ G PWQ I G + WILTAAH LR+ + Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 390 ------YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKD 443 ++ + D D V R++ H ++N Y +DIAL+++++ Sbjct: 61 PVSKEHVTVYLGLHDV--RDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGP 118 Query: 444 CELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN------------ERVFSLQWGEVKL 491 +P +P P P P+ +V+GWG N LQ+ ++ + Sbjct: 119 HVMPVCLPRLEPEGP---APHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPV 175 Query: 492 ISN--CSKFY----GNRFYEKEMECAGTYDGSIDACKGDSGGPLV-CMDANNVTYVWGVV 544 + + C Y GN + M CAG Y+G D C GDSGG V D + V G+V Sbjct: 176 VPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLV 235 Query: 545 SWG--ENCGKPEFPGVYTKVANYFDWISYHVGRP 576 SWG E CG + GVYTKV+NY DW+ +G P Sbjct: 236 SWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLP 269 >1SC8-U nrPDB Length = 262 Score = 234 bits (598), Expect = 6e-62, Method: Composition-based stats. Identities = 79/264 (29%), Positives = 124/264 (46%), Gaps = 17/264 (6%) Query: 324 KLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASG-----ITCGGIYIGGCWILTA 378 K CG K R +I+GG+ + + PW AI CGG I CW+++A Sbjct: 2 KFQCGQKTLRP--RFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISA 59 Query: 379 AHCL-RASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGT--YQNDIALIEM 435 HC K Y ++ + E V+ +I H++Y+A T + NDIAL+++ Sbjct: 60 THCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFE-VENLILHKDYSADTLAHHNDIALLKI 118 Query: 436 KKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS 493 + + +P Q +C ++G+G+E + ++ L+ VKLIS Sbjct: 119 RSKEGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLIS 178 Query: 494 N--CSK-FYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENC 550 + C + Y +M CA D+C+GDSGGPLVC +T + G+VSWG C Sbjct: 179 HRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMT-LTGIVSWGRGC 237 Query: 551 GKPEFPGVYTKVANYFDWISYHVG 574 + PGVYT+V+++ WI H Sbjct: 238 ALKDKPGVYTRVSHFLPWIRSHTK 261 >3F6U-H nrPDB Length = 240 Score = 234 bits (597), Expect = 9e-62, Method: Composition-based stats. Identities = 79/243 (32%), Positives = 117/243 (48%), Gaps = 14/243 (5%) Query: 341 VGGKRAQLGDLPWQVAIKDASGIT-CGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 + GK + GD PWQV + D+ CG + I W+LTAAHC+ SK ++ Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYD--- 58 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + K + + + H NY+ T NDIAL+ + + +P +P Sbjct: 59 LRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERE 118 Query: 460 LFQPNDTCIVSGWG------REKDNERVFSLQWGEVKLI--SNCSKFYGNRFYEKEMECA 511 L Q +V+GWG +E R F L + ++ ++ + CS+ N + M CA Sbjct: 119 LNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMV-SENMLCA 177 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 G DAC+GDSGGP+V + ++ G+VSWGE CG GVYTKV+ Y DWI Sbjct: 178 GILGDRQDACEGDSGGPMVA-SFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHG 236 Query: 572 HVG 574 H+ Sbjct: 237 HIR 239 >1A5I-A nrPDB Length = 265 Score = 234 bits (596), Expect = 9e-62, Method: Composition-based stats. Identities = 90/265 (33%), Positives = 131/265 (49%), Gaps = 21/265 (7%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAI------KDASGITCGGIYIGGCWILTAAH 380 CG++ + GG + PWQ AI CGGI I CW+LTAAH Sbjct: 2 CGLRKYKEPQLHST-GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAH 60 Query: 381 CLRASK-THRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDG 439 C + S + ++ + P + V + I H+ ++ TY NDIAL+++K D Sbjct: 61 CFQESYLPDQLKVVLGRTYRVKPGEEEQTF-KVKKYIVHKEFDDDTYNNDIALLQLKSDS 119 Query: 440 NKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLI--SNC 495 + E C+P + C +SG+G+ K + +S L+ G V+L S C Sbjct: 120 PQCAQESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRC 179 Query: 496 S-KFYGNRFYEKEMECAGTYDGSI------DACKGDSGGPLVCMDANNVTYVWGVVSWGE 548 + KF N+ M CAG DAC+GDSGGPLVCM+ N++T + G++SWG Sbjct: 180 APKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLL-GIISWGV 238 Query: 549 NCGKPEFPGVYTKVANYFDWISYHV 573 CG+ + PGVYTKV NY WI ++ Sbjct: 239 GCGEKDVPGVYTKVTNYLGWIRDNM 263 >1EUF-A nrPDB Length = 227 Score = 233 bits (593), Expect = 2e-61, Method: Composition-based stats. Identities = 70/242 (28%), Positives = 110/242 (45%), Gaps = 23/242 (9%) Query: 340 IVGGKRAQLGDLPWQVAI---KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG A+ P+ + CGG + ++LTAAHCL +S + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSS----INVTLGA 56 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + + + + VI V R I H +YN T NDI L+++ + + D P ++P + Sbjct: 57 HNIMERERTQQVI-PVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAE 115 Query: 457 SPYLFQPNDTCIVSGWGREKDNER-VFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 +P C V+GWGR N LQ ++++ S C + N + CAG Sbjct: 116 ----VKPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKN-YIPFTQICAGD 170 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 ++ GDSGGPLVC G+VS+G N G P VYT+++++ WI + Sbjct: 171 PSKRKNSFSGDSGGPLVCNGV-----AQGIVSYGRNDGT--TPDVYTRISSFLSWIHSTM 223 Query: 574 GR 575 R Sbjct: 224 RR 225 >1FI8-A nrPDB Length = 228 Score = 233 bits (593), Expect = 2e-61, Method: Composition-based stats. Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 23/243 (9%) Query: 340 IVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+GG A+ P+ ++ + CGG I ++LTAAHC + + Q+ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGS----KIQVTLG 56 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + I K I V +II H YN+ T NDI L+++K + P ++P Sbjct: 57 AHN-IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLP---- 111 Query: 456 WSPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAG 512 +P D C V+GWG+ + +LQ E+ + + C + N F + CAG Sbjct: 112 RRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAG 171 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYH 572 + +GDSGGPLVC G+VS+G+N G P +TKV+ + WI Sbjct: 172 DPKIKRASFRGDSGGPLVCKKV-----AAGIVSYGQNDGS--TPRAFTKVSTFLSWIKKT 224 Query: 573 VGR 575 + + Sbjct: 225 MKK 227 >3QUM-P nrPDB Length = 237 Score = 232 bits (592), Expect = 3e-61, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 108/250 (43%), Gaps = 33/250 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + PWQV + CGG+ + W+LTAAHC+R ++ I Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIR----NKSVILLGRHSL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTY-----------QNDIALIEMKKDGNKKDCELPR 448 HP+ V + V H Y+ +D+ L+ + + D Sbjct: 57 FHPEDTGQVFQ-VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVM 115 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFY 504 +P P TC SGWG + E + LQ ++ +ISN C++ + + Sbjct: 116 DLPTQEPAL------GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKV- 168 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVA 563 K M CAG + G C GDSGGPLVC + G+ SWG E C PE P +YTKV Sbjct: 169 TKFMLCAGRWTGGKSTCSGDSGGPLVCNGV-----LQGITSWGSEPCALPERPSLYTKVV 223 Query: 564 NYFDWISYHV 573 +Y WI + Sbjct: 224 HYRKWIKDTI 233 >1KIG-H nrPDB Length = 241 Score = 232 bits (591), Expect = 4e-61, Method: Composition-based stats. Identities = 75/238 (31%), Positives = 114/238 (47%), Gaps = 8/238 (3%) Query: 340 IVGGKRAQLGDLPWQVAIKDA-SGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IVGG+ G+ PWQ + + + CGG + ++LTAAHCL +K R+ + + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAK--RFTVRVGDRN 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + E V+ + H + TY DIA++ +K + P +P W+ Sbjct: 59 TEQEEGNEMAHE-VEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKD-WAE 116 Query: 459 YLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLISNCSKFYGNRF-YEKEMECAGTYDG 516 T IVSG+GR + R+ +L+ EV + + + F M CAG Sbjct: 117 ATLMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQ 176 Query: 517 SIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 DAC+GDSGGP V + +V G+VSWGE C + GVYTKV+N+ WI + Sbjct: 177 PEDACQGDSGGPHVTR-FKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMK 233 >4J1Y-A nrPDB Length = 397 Score = 231 bits (590), Expect = 5e-61, Method: Composition-based stats. Identities = 96/364 (26%), Positives = 145/364 (39%), Gaps = 49/364 (13%) Query: 231 NGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCIT--GE 288 NGK+ + C + DCG K + G I +Y C + G Sbjct: 53 NGKWSNSKLKCQPV-DCGIPESIENGKVEDPESTL--FGSVI--RYTCEEPYYYMENGGG 107 Query: 289 DEVGCAGFASVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQL 348 E CAG S E+L + + +P CGV + R +GG A + Sbjct: 108 GEYHCAGNGSWV---NEVLGPE-------LPKCVP--VCGVPREPFEEKARAIGGSDADI 155 Query: 349 GDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIV 408 + PWQV + GG I W+LTAAH + ++ + +T V L + Sbjct: 156 KNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQT--SRLAKSK 210 Query: 409 IEYVDRIIFHENYN-------AGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLF 461 + + + H + + NDIAL+ +K P +P S Y Sbjct: 211 MLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT--SSDYNL 268 Query: 462 QPNDTCIVSGWGREKDNERVFSLQWGEVKL--ISNCSKFYGNR--------FYEKEMECA 511 D ++SGWGR + +R L+ + + + C + + + M CA Sbjct: 269 MDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICA 328 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVT--YVWGVVSWGENCGKPEFPGVYTKVANYFDWI 569 G + +D+CKGDSGG D N+ T Y G+VSWG CG G+YT+V NY DWI Sbjct: 329 GG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT---YGLYTRVKNYVDWI 384 Query: 570 SYHV 573 + Sbjct: 385 MKTM 388 >6QHB-A nrPDB Length = 223 Score = 230 bits (587), Expect = 1e-60, Method: Composition-based stats. Identities = 71/236 (30%), Positives = 107/236 (45%), Gaps = 20/236 (8%) Query: 341 VGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWI 400 V G P+Q A+ + + CGG+ I W+LTAAHC K Q++ + + Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHN-L 56 Query: 401 HPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYL 460 V R + H +Y+A ++ DI L+ + + + P +P Sbjct: 57 GQQESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP------LPLERDC 110 Query: 461 FQPNDTCIVSGWGREKDNERVFSLQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYDGSI 518 +C + GWG+ D + ++Q + L+S C Y + + M CAG Sbjct: 111 SAQTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQI-TQNMLCAGDEKYGK 169 Query: 519 DACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHV 573 D+C+GDSGGPLVC D + G+VSWG CG E PGVYT V Y +WI + Sbjct: 170 DSCQGDSGGPLVCGDH-----LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 220 >2TLD-E nrPDB Length = 220 Score = 230 bits (586), Expect = 2e-60, Method: Composition-based stats. Identities = 73/238 (30%), Positives = 110/238 (46%), Gaps = 25/238 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG +P+QV++ ++ CGG I W+++AAHC ++ Q+ + Sbjct: 1 IVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKSG----IQVRLGEDNI 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + I + I H +YN+ T NDI LI++K + S+P Sbjct: 56 NVVEGNEQFIS-ASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCAS--- 111 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C++SGWG K + + L+ + ++S+ C Y + M CAG Sbjct: 112 ---AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQI-TSNMFCAGLEG 167 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 G D+C+GDSGGP+VC + G+VSWG C PGVYTKV NY WI + Sbjct: 168 G--DSCQGDSGGPVVCSGK-----LQGIVSWGSGCA-KNKPGVYTKVCNYVSWIKQTI 217 >3BSQ-A nrPDB Length = 227 Score = 229 bits (583), Expect = 4e-60, Method: Composition-based stats. Identities = 80/240 (33%), Positives = 112/240 (46%), Gaps = 24/240 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G G PWQVA+ + + CGG+ + W+LTAAHC K + Y + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 +RI + H Y+ T+ ND+ L+++ +P+ Sbjct: 57 GDRRAQRI---KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE---- 109 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYD 515 P TC VSGWG + F L +VKLIS +C+K Y + E M CAG D Sbjct: 110 --PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGIPD 166 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHVG 574 +AC GDSGGPLVC + G+VSWG CG+P PGVYT+V + WI+ + Sbjct: 167 SKKNACNGDSGGPLVCRGT-----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1Q3X-A nrPDB Length = 328 Score = 228 bits (582), Expect = 4e-60, Method: Composition-based stats. Identities = 82/270 (30%), Positives = 118/270 (43%), Gaps = 23/270 (8%) Query: 316 RRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWI 375 + + P CG+ R RI GG++A+ GD PWQV I G T G + W+ Sbjct: 67 KSLPVCEP--VCGLSARTT--GGRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWV 120 Query: 376 LTAAHCLRASKTHR--YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENY-NAGTYQNDIAL 432 LTAAH + K I + + P + E V HE Y + + NDIAL Sbjct: 121 LTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAV---FIHEGYTHDAGFDNDIAL 177 Query: 433 IEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI 492 I++ P +P + + +D SGWG + +L + ++ ++ Sbjct: 178 IKLNNKVVINSNITPICLPRK--EAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIV 235 Query: 493 SNCSKF-------YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDAN-NVTYVWGVV 544 + Y M CAG G D+C+GDSGG LV +D+ +V G+V Sbjct: 236 DHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIV 295 Query: 545 SWGE-NCGKPEFPGVYTKVANYFDWISYHV 573 SWG NCG+ GVYTKV NY WI + Sbjct: 296 SWGSMNCGEAGQYGVYTKVINYIPWIENII 325 >1SPJ-A nrPDB Length = 238 Score = 227 bits (579), Expect = 9e-60, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 104/251 (41%), Gaps = 34/251 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + PWQ A+ S CGGI + W+LTAAHC+ + YQ+W + Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCI----SDNYQLWLGRHNL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYN-----------AGTYQNDIALIEMKKDG-NKKDCELP 447 D +V H +N Y +D+ L+ + + D Sbjct: 57 F-DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKV 115 Query: 448 RSIPACVPWSPYLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLI--SNCSKFYGNRF 503 +P P + TC+ SGWG + LQ ++K++ C K + + Sbjct: 116 VELPTEEP------EVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKV 169 Query: 504 YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKV 562 + M C G +G D C GDSGGPL+C + GV SWG CG P P V +V Sbjct: 170 TDF-MLCVGHLEGGKDTCVGDSGGPLMCDGV-----LQGVTSWGYVPCGTPNKPSVAVRV 223 Query: 563 ANYFDWISYHV 573 +Y WI + Sbjct: 224 LSYVKWIEDTI 234 >5UBM-A nrPDB Length = 252 Score = 227 bits (578), Expect = 1e-59, Method: Composition-based stats. Identities = 73/254 (28%), Positives = 111/254 (43%), Gaps = 30/254 (11%) Query: 339 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 RI+GG A + + PWQV + GG I W+LTAAH + ++ + +T V Sbjct: 1 RIIGGSDADIKNFPWQVFFDNP---WAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 399 WIHPDLKRIVIEYVDRIIFHENYN-------AGTYQNDIALIEMKKDGNKKDCELPRSIP 451 L + + + + H + + NDIAL+ +K P +P Sbjct: 58 T--SRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 115 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKL--ISNCSKFYGNR------- 502 S Y D ++SGWGR + +R L+ + + + C + + Sbjct: 116 GT--SSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEA 173 Query: 503 -FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVT--YVWGVVSWGENCGKPEFPGVY 559 + M CAG + +D+CKGDSGG D N+ T Y G+VSWG CG G+Y Sbjct: 174 YVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT---YGLY 229 Query: 560 TKVANYFDWISYHV 573 T+V NY DWI + Sbjct: 230 TRVKNYVDWIMKTM 243 >1AO5-A nrPDB Length = 237 Score = 226 bits (577), Expect = 2e-59, Method: Composition-based stats. Identities = 69/250 (27%), Positives = 105/250 (42%), Gaps = 33/250 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 +VGG + PWQVA+ CGG+ + W+LTAAHC +Y++W Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY----VDQYEVWLGKNKL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNA-----------GTYQNDIALIEMKKDGNKKDCELPR 448 + V + H +N + +D+ L+ + K + D P Sbjct: 57 FQEEPS-AQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPI 115 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLI--SNCSKFYGNRFY 504 ++P P +P C+ SGWG ++ LQ + L+ NC+K Y + Sbjct: 116 ALPTKEP------KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKV- 168 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVA 563 M CAG G D C+ DSGGPL+C + G S+G CGKP P +YT + Sbjct: 169 TDVMLCAGEMGGGKDTCRDDSGGPLICDG-----ILQGTTSYGPVPCGKPGVPAIYTNLI 223 Query: 564 NYFDWISYHV 573 + WI + Sbjct: 224 KFNSWIKDTM 233 >4XDE-A nrPDB Length = 257 Score = 225 bits (574), Expect = 3e-59, Method: Composition-based stats. Identities = 78/243 (32%), Positives = 111/243 (45%), Gaps = 11/243 (4%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 +VGG A G P+ A+ C G I CW+LTAAHCL+ + Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS-FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKK-DCELPRSIPACVPWSP 458 + + V HE ++ +YQ+D+AL+ +++D + P P +P Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 459 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSK--FYGNRFYEKEMECAG 512 C V+GWG + + ++ LQ +V +S CS +G+ M CAG Sbjct: 122 ARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSIL-PGMLCAG 180 Query: 513 TYDGSIDACKGDSGGPLVCMDA--NNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWIS 570 +G DAC+GDSGGPLVC D + G++SWG CG PGVYT VA Y WI Sbjct: 181 FLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIR 240 Query: 571 YHV 573 H Sbjct: 241 EHT 243 >2EEK-A nrPDB Length = 220 Score = 225 bits (573), Expect = 5e-59, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 102/237 (43%), Gaps = 21/237 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG QV++ ++ CGG + W+++AAHC ++ ++ Sbjct: 1 IVGGYECTKHSQAHQVSL-NSGYHFCGGSLVSKDWVVSAAHCYKSV----LRVRLGEHHI 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + I +I H NY++ NDI LI++ K ++P Sbjct: 56 RVNEGTEQYISS-SSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADA- 113 Query: 460 LFQPNDTCIVSGWGREKDN-ERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDG 516 C VSGWG + LQ + ++S+ C+ Y + M CAG +G Sbjct: 114 -----TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMI-TQSMFCAGYLEG 167 Query: 517 SIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 D+C+GDSGGP+VC + GVVSWG C + + PGVY KV W+ + Sbjct: 168 GKDSCQGDSGGPVVCNGV-----LQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTM 219 >1NPM-A nrPDB Length = 225 Score = 224 bits (571), Expect = 7e-59, Method: Composition-based stats. Identities = 81/243 (33%), Positives = 112/243 (46%), Gaps = 26/243 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G+ PWQ A+ + CGG+ +G W+LTAAHC K +Y + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLGDHSL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENY---NAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 D I+ V + I H Y N + +DI LI ++ N D P + P Sbjct: 57 QSRDQPEQEIQ-VAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCP- 114 Query: 457 SPYLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAG 512 + CI+SGWG + +L EVK+ S C + Y + + M CAG Sbjct: 115 -----KVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKI-TEGMVCAG 168 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISY 571 + +G D C+GDSGGPLVC + G+ SWG CGKPE PGVYTK+ Y WI Sbjct: 169 SSNG-ADTCQGDSGGPLVCDG-----MLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKK 222 Query: 572 HVG 574 + Sbjct: 223 TMD 225 >1ZJK-A nrPDB Length = 403 Score = 224 bits (570), Expect = 1e-58, Method: Composition-based stats. Identities = 81/270 (30%), Positives = 118/270 (43%), Gaps = 23/270 (8%) Query: 316 RRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWI 375 + + P CG+ R +I GG++A+ GD PWQV I G T G + W+ Sbjct: 142 KSLPVCEP--VCGLSARTT--GGQIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWV 195 Query: 376 LTAAHCLRASKTHR--YQIWTTVVDWIHPDLKRIVIEYVDRIIFHENY-NAGTYQNDIAL 432 LTAAH + K I + + P + E V HE Y + + NDIAL Sbjct: 196 LTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAV---FIHEGYTHDAGFDNDIAL 252 Query: 433 IEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI 492 I++ P +P + + +D SGWG + +L + ++ ++ Sbjct: 253 IKLNNKVVINSNITPICLPRK--EAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIV 310 Query: 493 SNCSKF-------YGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDAN-NVTYVWGVV 544 + Y M CAG G D+C+GDSGG LV +D+ +V G+V Sbjct: 311 DHQKCTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIV 370 Query: 545 SWGE-NCGKPEFPGVYTKVANYFDWISYHV 573 SWG NCG+ GVYTKV NY WI + Sbjct: 371 SWGSMNCGEAGQYGVYTKVINYIPWIENII 400 >5MS3-A nrPDB Length = 228 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 79/243 (32%), Positives = 113/243 (46%), Gaps = 26/243 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG Q PWQ A+ + CGG+ +GG W+LTAAHC K +Y + Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC----KKPKYTVRLGDHSL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNA---GTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + D I V + I H YN+ + +D+ L++++ + P S+ Sbjct: 57 QNKDGPEQEI-PVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL------ 109 Query: 457 SPYLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKL--ISNCSKFYGNRFYEKEMECAG 512 + + QP C VSGWG +L EVK+ C Y + M CAG Sbjct: 110 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQI-TDGMVCAG 168 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISY 571 + G D C+GDSGGPLVC A + G+ SWG CG+ + PGVYT + Y DWI Sbjct: 169 SSKG-ADTCQGDSGGPLVCDGA-----LQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 222 Query: 572 HVG 574 +G Sbjct: 223 IIG 225 >5LHN-A nrPDB Length = 247 Score = 223 bits (568), Expect = 2e-58, Method: Composition-based stats. Identities = 74/249 (29%), Positives = 121/249 (48%), Gaps = 16/249 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDAS------GITCGGIYIGGCWILTAAHCL-RASKTHRYQI 392 IVGG+ ++ + PW AI + CGG I CW+ +AAHC + K Y + Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 393 WTTVVDWIHPDLKRIVIEYVDRIIFHENY--NAGTYQNDIALIEMKKDGNKKDCELPRSI 450 + + + E V+++I HE Y ++ Y NDIAL++++ + Sbjct: 61 YLGQSKESSYNPGEMKFE-VEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQ 119 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISNCSK---FYGNRFYE 505 +P C ++G+G+E +++ ++ L+ VKL+S+ Y Sbjct: 120 TIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEIN 179 Query: 506 KEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANY 565 +M CA + D+CKGDSGGPL+C + G+VSWG C + PGVYT+V+++ Sbjct: 180 YKMLCAADPEWKTDSCKGDSGGPLICN-IEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHF 238 Query: 566 FDWISYHVG 574 DWI H+G Sbjct: 239 LDWIQSHIG 247 >4FXG-H nrPDB Length = 242 Score = 223 bits (567), Expect = 2e-58, Method: Composition-based stats. Identities = 76/246 (30%), Positives = 110/246 (44%), Gaps = 19/246 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHR--YQIWTTVV 397 I GG++A+ GD PWQV I G T G + W+LTAAH + K I + Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 398 DWIHPDLKRIVIEYVDRIIFHENY-NAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + P + E V HE Y + + NDIALI++ P +P Sbjct: 59 KRLSPHYTQAWSEAV---FIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRK--E 113 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKF-------YGNRFYEKEME 509 + + +D SGWG + +L + ++ ++ + Y M Sbjct: 114 AESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANML 173 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDAN-NVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFD 567 CAG G D+C+GD+GG LV +D+ +V G+VSWG NCG+ GVYTKV NY Sbjct: 174 CAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIP 233 Query: 568 WISYHV 573 WI + Sbjct: 234 WIENII 239 >1FDP-A nrPDB Length = 235 Score = 222 bits (565), Expect = 4e-58, Method: Composition-based stats. Identities = 67/246 (27%), Positives = 112/246 (45%), Gaps = 21/246 (8%) Query: 335 IRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWT 394 R RI+GG+ A+ P+ +++ CGG+ + W+L+AAHCL + + Q+ Sbjct: 3 PPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLL 62 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 454 P+ + + + V R + H + T +D+ L+++ + P + Sbjct: 63 GAHSLSQPEPSKRLYD-VLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRP------L 115 Query: 455 PWS--PYLFQPNDTCIVSGWGRE-KDNERVFSLQWGEVKLISNCS---KFYGNRFYEKEM 508 PW P C V+GWG R SLQ + ++ + + + + + + Sbjct: 116 PWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERL 175 Query: 509 ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFD 567 CA D+CKGDSGGPLVC + GVV+ G CG + PG+YT+VA+Y Sbjct: 176 MCA--ESNRRDSCKGDSGGPLVCGGV-----LEGVVTSGSRVCGNRKKPGIYTRVASYAA 228 Query: 568 WISYHV 573 WI + Sbjct: 229 WIDSVL 234 >5ZFH-A nrPDB Length = 224 Score = 222 bits (565), Expect = 4e-58, Method: Composition-based stats. Identities = 80/240 (33%), Positives = 111/240 (46%), Gaps = 24/240 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G + + G PWQVA+ + + CGG+ + W+LTAAHC K +YQ+ Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHC----KMGQYQVQLGSDKI 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 ++I + H Y+ T+ NDI L+ + + +P Sbjct: 57 GDQSAQKI---KATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCE---- 109 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYD 515 P +C VSGWG + F L +VKLIS C K Y + K M CAG D Sbjct: 110 --PPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKD-LLGKTMLCAGIPD 166 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWISYHVG 574 + C GDSGGPLVC D + G+VSWG CG+P PGVYT+V Y W+ + Sbjct: 167 SKTNTCNGDSGGPLVCNDT-----LQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >3TK9-A nrPDB Length = 226 Score = 221 bits (563), Expect = 7e-58, Method: Composition-based stats. Identities = 66/241 (27%), Positives = 106/241 (43%), Gaps = 21/241 (8%) Query: 340 IVGGKRAQLGDLPWQVA---IKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG A+ P+ +++ S CGGI + ++LTAAHC +S + Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSS----INVTLGA 56 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + I + V R I H YN + N+I L+++++ P +P+ Sbjct: 57 HN-IKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPS---- 111 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCS--KFYGNRFYEKEMECAGTY 514 S +P C V+GWG + +LQ + + +C + + + C G Sbjct: 112 SKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDP 171 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 + KGDSGGPLVC D G++S+G G P PGVY KV+++ WI + Sbjct: 172 KKTQTGFKGDSGGPLVCKDV-----AQGILSYGNKKGTP--PGVYIKVSHFLPWIKRTMK 224 Query: 575 R 575 R Sbjct: 225 R 225 >1MD7-A nrPDB Length = 328 Score = 220 bits (561), Expect = 1e-57, Method: Composition-based stats. Identities = 76/272 (27%), Positives = 123/272 (45%), Gaps = 28/272 (10%) Query: 317 RIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWIL 376 +I LP CG +R+RI+GG++A++G+ PWQV GG +G WIL Sbjct: 69 KIPRCLP--VCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWIL 124 Query: 377 TAAHCLR-----ASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAG---TYQN 428 TAAH L A ++ + +L ++ + R+ H +Y ++ Sbjct: 125 TAAHTLYPKEHEAQSNASLDVFLGHTNV--EELMKLGNHPIRRVSVHPDYRQDESYNFEG 182 Query: 429 DIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGE 488 DIAL+E++ P +P C+P + + VSG+G ++ + L++ Sbjct: 183 DIALLELENSVTLG----PNLLPICLPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVR 237 Query: 489 VKLISN--CSKFYGNR----FYEKEMECAGTYDGSIDACKGDSGGPLVCMDAN-NVTYVW 541 + + + C + + + + M CAG DAC+GD+GG D N + Sbjct: 238 LPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVAT 297 Query: 542 GVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 G+VSWG C + G YTKV NY DWI + Sbjct: 298 GIVSWGIGCSRG--YGFYTKVLNYVDWIKKEM 327 >4DJZ-B nrPDB Length = 251 Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats. Identities = 77/255 (30%), Positives = 115/255 (45%), Gaps = 27/255 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGI-TCGGIYIGGCWILTAAHCLRASK------------ 386 I G+ AQ G PW + +G CGG +G WI+TAAHCL S Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 387 --THRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDC 444 ++I + D V H Y+ T++ND+AL+E+ + Sbjct: 61 LSPSDFKIILGKHWRLRSDENE-QHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAF 119 Query: 445 ELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGN- 501 +P +P Q IVSGWG++ +L E+ ++ + C K Y Sbjct: 120 VMPICLP------EGPQQEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHSTCQKAYAPL 173 Query: 502 -RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEFPGVY 559 + ++M CAG +G DAC GDSGGP+V ++ Y+ G VSWG++CGK + GVY Sbjct: 174 KKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVY 233 Query: 560 TKVANYFDWISYHVG 574 + + + DWI G Sbjct: 234 SYIHHNKDWIQRVTG 248 >1MZD-A nrPDB Length = 240 Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats. Identities = 68/246 (27%), Positives = 105/246 (42%), Gaps = 20/246 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHC-LRASKTHRYQIWTTVVD 398 I+GGK P+ +I+ CGG+ I W+LTAAHC R +K + Sbjct: 3 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 62 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + +E + + I + NDI L++++ I S Sbjct: 63 LSKNEASKQTLE-IKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI-----RSK 116 Query: 459 YLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLIS----NCSKFY-GNRFYEKEMECA 511 + C V+GWG + +L+ V ++S N +Y G+ F K+M CA Sbjct: 117 TSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 176 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVA-NYFDWIS 570 G G D+CKGD+GGPL+C + +VS G CG PG+YT + Y WI Sbjct: 177 GDAKGQKDSCKGDAGGPLICKGVFHA-----IVSGGHECGVATKPGIYTLLTKKYQTWIK 231 Query: 571 YHVGRP 576 ++ P Sbjct: 232 SNLVPP 237 >2OLG-A nrPDB Length = 278 Score = 219 bits (557), Expect = 4e-57, Method: Composition-based stats. Identities = 75/286 (26%), Positives = 115/286 (40%), Gaps = 35/286 (12%) Query: 315 RRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASG-----ITCGGIY 369 R R LLP CG + +I+ G + PW I + CGG Sbjct: 3 RNRRPELLPN-DCG----YQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSL 57 Query: 370 IGGCWILTAAHCLRASKTHRY----QIWTTVVDWIHPD----------LKRIVIEYVDRI 415 I +I+TAAHC+ ++ + + + ++ Sbjct: 58 INNRYIVTAAHCVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEET 117 Query: 416 IFHENYNAGTYQ--NDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWG 473 I H +Y G+ +DIALI + + + P C+P Q V GWG Sbjct: 118 IQHPDYVDGSKDRYHDIALIRLNRQVEFTNYIR----PVCLPQPNEEVQVGQRLTVVGWG 173 Query: 474 REKDNERVFSLQWGEVKLI--SNCSKFYG--NRFYEKEMECAGTYDGSIDACKGDSGGPL 529 R + + Q V ++ C+K +G CAG + + D+C GDSGGPL Sbjct: 174 RTETGQYSTIKQKLAVPVVHAEQCAKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPL 232 Query: 530 VCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGR 575 + AN ++ G+VS+G CG +PG+YTKV Y DWI ++ Sbjct: 233 LAERANQQFFLEGLVSFGATCGTEGWPGIYTKVGKYRDWIEGNIRP 278 >5TO3-B nrPDB Length = 409 Score = 218 bits (555), Expect = 6e-57, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 100/257 (38%), Gaps = 22/257 (8%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASK------THRYQ 391 IV G A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSI 450 + + I +++I H YN DIAL+++KK D P + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDN-------ERVFSLQWGEVKLISNCSKFYGNRF 503 P + L Q V+GWG K+ + LQ + ++ R Sbjct: 121 PD-RETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 179 Query: 504 -YEKEMECAGT---YDGSIDACKGDSGGPLVCMDA-NNVTYVWGVVSWGENCGKPEFPGV 558 M CAG DAC+GDSGGP V NN Y G+VS G C + G Sbjct: 180 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAGCDRDGKYGF 239 Query: 559 YTKVANYFDWISYHVGR 575 YT V WI + + Sbjct: 240 YTHVFRLKKWIQKVIDQ 256 >1NN6-A nrPDB Length = 228 Score = 218 bits (554), Expect = 7e-57, Method: Composition-based stats. Identities = 61/239 (25%), Positives = 104/239 (43%), Gaps = 21/239 (8%) Query: 340 IVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+GG + P+ ++ + CGG I ++LTAAHC S + Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRS----ITVTLG 58 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + + +E + + H YN T +DI L+++K+ + ++P P Sbjct: 59 AHNITEEEDTWQKLEVIKQ-FRHPKYNTSTLHHDIMLLKLKEKASLTLAVG--TLP--FP 113 Query: 456 WSPYLFQPNDTCIVSGWGREKDNER-VFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTY 514 P C V+GWGR + +LQ +++L+ + + F C G Sbjct: 114 SQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNP 173 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 + A KGDSGGPL+C G+VS+G + KP P V+T++++Y WI+ + Sbjct: 174 RKTKSAFKGDSGGPLLCAGV-----AQGIVSYGRSDAKP--PAVFTRISHYRPWINQIL 225 >2PSX-A nrPDB Length = 227 Score = 218 bits (554), Expect = 8e-57, Method: Composition-based stats. Identities = 68/240 (28%), Positives = 112/240 (46%), Gaps = 23/240 (9%) Query: 340 IVGGKRAQLGDLPWQVAIK-DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 I+ G + PWQ A+ + + CG + + W+LTAAHC K R ++ + Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC--RKKVFRVRLGHYSLS 58 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 ++ +++ + V + I H Y+ + ND+ LI++ + P ++ + P Sbjct: 59 PVYESGQQM-FQGV-KSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS-- 114 Query: 459 YLFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 C+VSGWG K + LQ + ++S C Y R + M CAG Sbjct: 115 ----AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP-RQIDDTMFCAGD- 168 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHV 573 D+C+GDSGGP+VC + + G+VSWG+ C +P PGVYT + + WI + Sbjct: 169 KAGRDSCQGDSGGPVVCNGS-----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 223 >1SGF-A nrPDB Length = 240 Score = 218 bits (554), Expect = 9e-57, Method: Composition-based stats. Identities = 72/241 (29%), Positives = 108/241 (44%), Gaps = 33/241 (13%) Query: 349 GDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIV 408 PW VA+ + CGG+ + W+LTAAHC +YQ+W +++ + Sbjct: 13 NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCY----NDKYQVWLGKNNFLEDEPSD-Q 67 Query: 409 IEYVDRIIFHENYNA-----------GTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 V + I H ++N Y ND+ L+ + K + D P ++P P Sbjct: 68 HRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEP-- 125 Query: 458 PYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 + TC+ SGWG + + LQ +KL+ N C K + + M CAG Sbjct: 126 ----KLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKV-TDAMLCAGE 180 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWISYH 572 DG C+ DSGGPL+C + G+ SWG E CG+P P VYTK+ + WI Sbjct: 181 MDGGSYTCEHDSGGPLICDG-----ILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRET 235 Query: 573 V 573 + Sbjct: 236 M 236 >1GPZ-A nrPDB Length = 399 Score = 217 bits (553), Expect = 9e-57, Method: Composition-based stats. Identities = 76/272 (27%), Positives = 123/272 (45%), Gaps = 28/272 (10%) Query: 317 RIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWIL 376 +I LP CG +R++I+GG++A++G+ PWQV GG +G WIL Sbjct: 137 KIPRCLP--VCGKPVNPVEQRQQIIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWIL 192 Query: 377 TAAHCLR-----ASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAG---TYQN 428 TAAH L A ++ + +L ++ + R+ H +Y ++ Sbjct: 193 TAAHTLYPKEHEAQSNASLDVFLGHTNV--EELMKLGNHPIRRVSVHPDYRQDESYNFEG 250 Query: 429 DIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGE 488 DIAL+E++ P +P C+P + + VSG+G ++ + L++ Sbjct: 251 DIALLELENSVTLG----PNLLPICLPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVR 305 Query: 489 VKLISN--CSKFYGNR----FYEKEMECAGTYDGSIDACKGDSGGPLVCMDAN-NVTYVW 541 + + + C + + + + M CAG DAC+GDSGG D N + Sbjct: 306 LPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVAT 365 Query: 542 GVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 G+VSWG C + G YTKV NY DWI + Sbjct: 366 GIVSWGIGCSRG--YGFYTKVLNYVDWIKKEM 395 >1TON-A nrPDB Length = 235 Score = 217 bits (553), Expect = 9e-57, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 108/251 (43%), Gaps = 35/251 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG + + PWQVA+ + CGG+ I W++TAAHC ++ YQ+ + Sbjct: 1 IVGGYKCEKNSQPWQVAVINE--YLCGGVLIDPSWVITAAHCY----SNNYQVLLGRNNL 54 Query: 400 IHPDLKRIVIEYVDRIIFHENYNA-----------GTYQNDIALIEMKKDGNKKDCELPR 448 D V + H +Y + ND+ L+ + + + Sbjct: 55 FK-DEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVI 113 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFY 504 +P P + TC+ SGWG +E V S LQ + L+SN C + Y + Sbjct: 114 DLPTKEP------KVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNV- 166 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVA 563 M CAG +G D C GDSGGPL+C + G+ S G C KP+ P +Y K+ Sbjct: 167 TDVMLCAGEMEGGKDTCAGDSGGPLICDGV-----LQGITSGGATPCAKPKTPAIYAKLI 221 Query: 564 NYFDWISYHVG 574 + WI + Sbjct: 222 KFTSWIKKVMK 232 >2V35-A nrPDB Length = 240 Score = 217 bits (553), Expect = 1e-56, Method: Composition-based stats. Identities = 69/246 (28%), Positives = 107/246 (43%), Gaps = 21/246 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG----ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG AQ P Q++++ SG TCGG I W++TAAHC+ T R + Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTY--QNDIALIEMKKDGNKKDCELPRSIPAC 453 ++ + V +I+ H +N DIAL+ + + +P Sbjct: 61 NLNQNDGTEQ---YVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLP-- 115 Query: 454 VPWSPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLIS---NCSKFYGNRFYEKEME 509 + + N C ++GWG + N ++ +LQ + + S Y + M Sbjct: 116 --RAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMV 173 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE--NCGKPEFPGVYTKVANYFD 567 CAG DG C+GDSGGPL C+ N V GV S+ C P V+T+V+ Y Sbjct: 174 CAGG-DGVRSGCQGDSGGPLHCL-VNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYIS 231 Query: 568 WISYHV 573 WI+ + Sbjct: 232 WINNVI 237 >2BDH-A nrPDB Length = 223 Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats. Identities = 71/237 (29%), Positives = 106/237 (44%), Gaps = 19/237 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+ G+ PWQ A+ + + C G+ + W+L+AAHC + S Y I + Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS----YTIGLGLHSL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + H YN ND+ LI++ + ++ D SI + P Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--- 113 Query: 460 LFQPNDTCIVSGWGREKDNERVFSLQW--GEVKLISNCSKFYGNRFYEKEMECAGTYDGS 517 ++C+VSGWG + LQ V CSK Y + Y M CAG Sbjct: 114 ---AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGQDQ 169 Query: 518 IDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHV 573 D+C GDSGGPL+C Y+ G+VS+G+ CG+ PGVYT + + +WI V Sbjct: 170 KDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 221 >1ELT-A nrPDB Length = 236 Score = 214 bits (546), Expect = 6e-56, Method: Composition-based stats. Identities = 68/246 (27%), Positives = 115/246 (46%), Gaps = 22/246 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG----ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 +VGG+ AQ PWQ++++ SG TCGG I W++TAAHC+ +++T R + Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTY--QNDIALIEMKKDGNKKDCELPRSIPAC 453 ++ + + I V+ + H +N+ DIAL+ + + A Sbjct: 61 NLNT---NEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQL----AA 113 Query: 454 VPWSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISNCSKF---YGNRFYEKEME 509 +P S + N+ C ++GWG+ + SL+ + + + + + + M Sbjct: 114 LPPSNQILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMV 173 Query: 510 CAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSW--GENCGKPEFPGVYTKVANYFD 567 CAG G+ C GDSGGPL C N YV GV S+ C + P V+T+V+ Y Sbjct: 174 CAGG--GANSGCNGDSGGPLNCQ-VNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYIS 230 Query: 568 WISYHV 573 W++ + Sbjct: 231 WMNGIM 236 >1IAU-A nrPDB Length = 227 Score = 214 bits (546), Expect = 6e-56, Method: Composition-based stats. Identities = 66/242 (27%), Positives = 104/242 (42%), Gaps = 22/242 (9%) Query: 340 IVGGKRAQLGDLPWQVAI---KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG A+ P+ + S CGG I ++LTAAHC +S + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSS----INVTLGA 56 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + I V R I H YN + NDI L+++++ + P +P+ Sbjct: 57 HN-IKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPS---- 111 Query: 457 SPYLFQPNDTCIVSGWGREKD-NERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 + +P TC V+GWG+ + +LQ ++ + + C + + C G Sbjct: 112 NKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGD 171 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 + + KGDSGGPLVC G+VS+G N G P P TKV+++ WI + Sbjct: 172 PEIKKTSFKGDSGGPLVCNKV-----AQGIVSYGRNNGMP--PRACTKVSSFVHWIKKTM 224 Query: 574 GR 575 R Sbjct: 225 KR 226 >5FCR-A nrPDB Length = 234 Score = 213 bits (543), Expect = 2e-55, Method: Composition-based stats. Identities = 65/241 (26%), Positives = 107/241 (44%), Gaps = 18/241 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTTVVD 398 I+GG+ A P+ +++ CGG + W+L+AAHC+ + Q+ Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 P+ + + V ++ H + ++D+ L ++ ++ + P P + + Sbjct: 61 LSAPEPYKRWYD-VQSVVPHPGSRPDSLEDDLILFKLSQNASLG----PHVRPLPLQYED 115 Query: 459 YLFQPNDTCIVSGWG-REKDNERVFSLQWGEVKLISN--CS-KFYGNRFYEKEMECAGTY 514 +P C V+GWG R L V +++ C+ + Y + M CA Sbjct: 116 KEVEPGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--E 173 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHV 573 D C+GDSG PLVC DA V GVV+WG CG + PGVYT+V++Y WI Sbjct: 174 SNRRDTCRGDSGSPLVCGDA-----VEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENIT 228 Query: 574 G 574 Sbjct: 229 N 229 >1YM0-A nrPDB Length = 238 Score = 212 bits (541), Expect = 2e-55, Method: Composition-based stats. Identities = 71/242 (29%), Positives = 112/242 (46%), Gaps = 15/242 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG--ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 IVGG A+ + PWQV+++ S CGG I W++ AAHC++ + Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 D R + VD I +ENY+ T +ND+++I+ P P P + Sbjct: 61 DSSAASTVRQTHD-VDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPD--PAN 117 Query: 458 PYLFQPNDTCIVSGWGREKDNER--VFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 Y+++ C SGWG L++ + + +N C Y + +M CA Sbjct: 118 DYVYRK-SQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATD 174 Query: 514 YDG--SIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 G D+C+GDSGGPL D + + + G+VSWG C +PGVY++V + WI+ Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIGCAS-GYPGVYSRVGFHAGWITD 233 Query: 572 HV 573 + Sbjct: 234 TI 235 >5KWM-A nrPDB Length = 230 Score = 212 bits (541), Expect = 3e-55, Method: Composition-based stats. Identities = 66/244 (27%), Positives = 108/244 (44%), Gaps = 20/244 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGI-TCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IVGG+ A + D P+ VA+ G CGG ++TAAHC S+ + + Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + + V + H Y D++++ ++ + EL ++ Sbjct: 61 MSSNEG---TVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEAPIELAKAD-------D 110 Query: 459 YLFQPNDTCIVSGWGREKDNER-VFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 + P+ + GWG + + LQ V + S+ C + YG + M CAG + Sbjct: 111 AGYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGE-YTPDAMVCAGVPE 169 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGR 575 G +D C+GDSGGP+V + + GV SWGE C +P PGVY +V Y+D + + Sbjct: 170 GGVDTCQGDSGGPMVVNNK-----LIGVTSWGEGCARPGKPGVYARVGAYYDVLMEQINA 224 Query: 576 PFIS 579 +S Sbjct: 225 GAVS 228 >1OP0-A nrPDB Length = 234 Score = 212 bits (539), Expect = 4e-55, Method: Composition-based stats. Identities = 63/239 (26%), Positives = 96/239 (40%), Gaps = 20/239 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + + VA + +G CGG I W++TAAHC S + Q+ Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHC--DSTDFQMQLGVHSKKV 58 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 ++ D + + ++ I N DI LI++ K + A + Sbjct: 59 LNEDEQTRNPK--EKFICPNKNNNEVLDKDIMLIKLDKPISNSKHI------APLSLPSS 110 Query: 460 LFQPNDTCIVSGWGREKD--NERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG + L+ + C Y E CAG Sbjct: 111 PPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQ 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWISYHV 573 G D C GDSGGPL+C G+VS+G CG+ PG+YT V +Y DWI ++ Sbjct: 171 GGKDTCGGDSGGPLICNGQ-----FQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNI 224 >3RP2-A nrPDB Length = 224 Score = 211 bits (537), Expect = 7e-55, Method: Composition-based stats. Identities = 60/240 (25%), Positives = 104/240 (43%), Gaps = 21/240 (8%) Query: 340 IVGGKRAQLGDLPWQVAI----KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+GG + P+ + + + CGG I ++LTAAHC K + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC----KGREITVILG 56 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 D + + I V++ I HE+YN+ +DI L++++K +P +P Sbjct: 57 AHDVRKRESTQQKI-KVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAV--NVVP--LP 111 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISNCSKFYGNRFYEKEMECAGTY 514 P C +GWG+ + ++L+ E++++ + + K C G+ Sbjct: 112 SPSDFIHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSP 171 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 A GDSGGPL+C G+VS+G KP P ++T+V+ Y WI+ + Sbjct: 172 TTLRAAFMGDSGGPLLCAGV-----AHGIVSYGHPDAKP--PAIFTRVSTYVPWINAVIN 224 >1FUJ-A nrPDB Length = 221 Score = 211 bits (536), Expect = 9e-55, Method: Composition-based stats. Identities = 61/240 (25%), Positives = 89/240 (37%), Gaps = 24/240 (10%) Query: 340 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 IVGG AQ P+ +++ + CGG I ++LTAAHCLR + Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + + V ++ NY+A NDI LI++ N +P Sbjct: 61 HNVRTQEP-TQQHFSVAQVFL-NNYDAENKLNDILLIQLSSPANLSASVATVQLP----Q 114 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLISNCSKFYGNRFYEKEMECAGTYD 515 C+ GWGR ++ LQ V ++ F C Sbjct: 115 QDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV--------TFFCRPHNICTFVPR 166 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHVG 574 C GDSGGPL+C + G+ S+ C FP +T+VA Y DWI + Sbjct: 167 RKAGICFGDSGGPLICDG-----IIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1BQY-A nrPDB Length = 234 Score = 210 bits (535), Expect = 1e-54, Method: Composition-based stats. Identities = 60/239 (25%), Positives = 96/239 (40%), Gaps = 20/239 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 + GG + + V + +++G CGG I W++TAAHC ++ +Q+ V Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHC----DSNNFQLLFGVHSK 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + ++ DI LI++ + + A + Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHI------APLSLPSS 110 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG+ + ++ + ++ + C Y R CAG Sbjct: 111 PPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQ 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSW-GENCGKPEFPGVYTKVANYFDWISYHV 573 G D C DSGGPL+C G+VSW G CG+P PGVYTKV +Y DWI + Sbjct: 171 GGRDTCHFDSGGPLICNG-----IFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >4GSO-A nrPDB Length = 232 Score = 210 bits (535), Expect = 1e-54, Method: Composition-based stats. Identities = 64/239 (26%), Positives = 100/239 (41%), Gaps = 22/239 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + P+ + G CG I W++TAAHC S + Q+ Sbjct: 1 VLGGDECDINEHPFLAFLYS-HGYFCGLTLINQEWVVTAAHC--DSTNFQMQLGVHSKKV 57 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 ++ D + + ++ I + DI LI++ K + P S+P+ P Sbjct: 58 LNEDEQTRNPK--EKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPS--- 112 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYD 515 C + GWG + + L+ C Y N K CAG + Sbjct: 113 ---VGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAY-NGLPAKTTLCAGVLE 168 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWISYHV 573 G D C GDSGGPL+C G+VS+G +CG+ PG+YT V +Y DWI ++ Sbjct: 169 GGKDTCVGDSGGPLICNGQ-----FQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >3G01-A nrPDB Length = 227 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 60/242 (24%), Positives = 100/242 (41%), Gaps = 23/242 (9%) Query: 340 IVGGKRAQLGDLPWQV----AIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+GG P+ + CGG + ++LTAAHC K + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC----KGRSMTVTLG 56 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + I + I V + I H +YN NDI L+++ ++ + P ++P Sbjct: 57 AHN-IKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLP---- 111 Query: 456 WSPYLFQPNDTCIVSGWGR-EKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAG 512 +P D C V+GWG+ D E +L ++ + + C + + + C G Sbjct: 112 RRNAHVKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVG 171 Query: 513 TYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYH 572 + +GDSGGPLVC G+VS+G+ G P V+T+V ++ WI Sbjct: 172 DSKIKGASFRGDSGGPLVCK-----RAAAGIVSYGQTDGSA--PQVFTRVLSFVSWIKKT 224 Query: 573 VG 574 + Sbjct: 225 MK 226 >3S9B-A nrPDB Length = 234 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 63/239 (26%), Positives = 97/239 (40%), Gaps = 20/239 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDA--SGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 +VGG + + P+ VA+ + S I C G I W+LTAAHC + R ++ Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHC--DRRNIRIKLGMHSK 58 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 + + D + V + DI LI +++ P S+P+ Sbjct: 59 NIRNEDEQIRVPRG--KYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPS----- 111 Query: 458 PYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG+ + ++ + C Y + CAG Sbjct: 112 -RSRGVGSRCRIMGWGKISTTTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILK 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWISYHV 573 G D C GDSGGPL+C + G+V+ G E CG+ P VYTKV +Y +WI + Sbjct: 171 GGRDTCHGDSGGPLICNGE-----MHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >4BXW-A nrPDB Length = 423 Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats. Identities = 90/380 (23%), Positives = 151/380 (39%), Gaps = 41/380 (10%) Query: 228 QCVNGKYISQMKACDGIND----CGDQSDELCCKACQGKGFHCKSGVCIP------SQYQ 277 QC + + DGI C + C+ K +G C + Q Sbjct: 49 QCSSNPCHYRGICKDGIGSYTCTCLSGYEGKNCERVLYKSCRVDNGNCWHFCKHVQNDIQ 108 Query: 278 CNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRIKSLLPKLSCGV------KN 331 C+ + GED C + + R + ++ LP K+ Sbjct: 109 CSCAEGYLLGEDGHSCVAGGNFS-------CGRNIKTRNKREANLPDFVQSQNATLLKKS 161 Query: 332 RMHIRRKRIVGGKRAQLGDLPWQVAIKD-ASGITCGGIYIGGCWILTAAHCLRASKTHRY 390 RIV G +LG+ PWQ A+ D G+ CGG + ++LTAAHC+ ++T Sbjct: 162 DNPSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISV 221 Query: 391 QIWTTVVDWIHPDLKRIVIEYVDRIIFHENY---------NAGTYQNDIALIEMKKDGNK 441 + + ++ + VD+I H+ + + Y DIA+I+MK Sbjct: 222 VVG----EIDKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQF 277 Query: 442 KDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNER-VFSLQWGEVKLISNCSKFYG 500 + +P +P ++ + D IVSG+GR + +L+ +V + + Sbjct: 278 SENVVPACLPTAD-FANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVS 336 Query: 501 NRF-YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVY 559 + M CAG DAC+GDSGGP + + ++ G+VS GE C + G Y Sbjct: 337 SETPITPNMFCAGYDTLPRDACQGDSGGPHTTV-YRDTHFITGIVSSGEGCARNGKYGNY 395 Query: 560 TKVANYFDWISYHVGRPFIS 579 TK++ + WI + + S Sbjct: 396 TKLSKFIPWIKRIMRQKLPS 415 >4WJG-C nrPDB Length = 315 Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats. Identities = 73/318 (22%), Positives = 122/318 (38%), Gaps = 41/318 (12%) Query: 275 QYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMH 334 +YQC T D G ++ E+ I A D ++ + CG Sbjct: 17 RYQCKNYYKLRTEGD-----GVYTLNNEKQWINKAVGD----KLPEC--EAVCGKPKNPA 65 Query: 335 IRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWT 394 +RI+GG G PWQ + +T G I W+LT A L + + Sbjct: 66 NPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKD 125 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACV 454 K+ ++E +++++ H NY+ DI LI++K+ + + R +P C+ Sbjct: 126 IAPTLTLYVGKKQLVE-IEKVVLHPNYSQV----DIGLIKLKQKVSVNE----RVMPICL 176 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKL--ISNCSKFYGNRFYE------- 505 P Y + VSGWGR + + L++ + + C + Y Sbjct: 177 PSKDYA-EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKS 235 Query: 506 ---------KEMECAGTYDGSIDACKGDSGGPLVCMD-ANNVTYVWGVVSWGENCGKPEF 555 + CAG D C GD+G D + Y G++S+ ++C E Sbjct: 236 PVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAE- 294 Query: 556 PGVYTKVANYFDWISYHV 573 GVY KV + DW+ + Sbjct: 295 YGVYVKVTSIQDWVQKTI 312 >2QY0-B nrPDB Length = 242 Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats. Identities = 70/249 (28%), Positives = 113/249 (45%), Gaps = 26/249 (10%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLR-----ASKTHRYQIWT 394 I+GG++A++G+ PWQV GG +G WILTAAH L A ++ Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAG---TYQNDIALIEMKKDGNKKDCELPRSIP 451 + +L ++ + R+ H +Y ++ DIAL+E++ P +P Sbjct: 59 GHTNV--EELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLG----PNLLP 112 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNR----FYE 505 C+P + + VSG+G ++ + L++ + + + C + + + Sbjct: 113 ICLPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMDVFS 171 Query: 506 KEMECAGTYDGSIDACKGDSGGPLVCMDAN-NVTYVWGVVSWGENCGKPEFPGVYTKVAN 564 + M CAG DAC+GDSGG D N + G+VSWG C + G YTKV N Sbjct: 172 QNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRG--YGFYTKVLN 229 Query: 565 YFDWISYHV 573 Y DWI + Sbjct: 230 YVDWIKKEM 238 >1KYN-A nrPDB Length = 235 Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 109/240 (45%), Gaps = 22/240 (9%) Query: 340 IVGGKRAQLGDLPWQVAIK---DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 I+GG+ ++ P+ ++ A CGG + ++LTAAHC + + Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGS----NINVTLGA 56 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 + I R I H YN T QNDI L+++ + + P ++P Sbjct: 57 HN-IQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALP----R 111 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 + +P C V+GWGR +L+ ++++ + C + +G+ + + C G Sbjct: 112 AQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGS-YDPRRQICVGDR 170 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 A KGDSGGPL+C + G+VS+G++ G P P V+T+V+++ WI + Sbjct: 171 RERKAAFKGDSGGPLLCNNV-----AHGIVSYGKSSGVP--PEVFTRVSSFLPWIRTTMR 223 >3S69-A nrPDB Length = 234 Score = 206 bits (525), Expect = 2e-53, Method: Composition-based stats. Identities = 61/239 (25%), Positives = 92/239 (38%), Gaps = 20/239 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + VA +++G C G I W+LTAAHC +Q+ V Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHC----DNTNFQMKLGVHSK 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + ++ I N DI LI++ + + + Sbjct: 57 KVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHI------VPLSLPSS 110 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 C + GWG + + + L+ + C Y E CAG + Sbjct: 111 PPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWISYHV 573 G D C GDSGGPL+C G+VS+G CG+ PGVYTKV +Y WI + Sbjct: 171 GGKDTCGGDSGGPLICNGQ-----FQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >2AIQ-A nrPDB Length = 231 Score = 206 bits (524), Expect = 2e-53, Method: Composition-based stats. Identities = 61/238 (25%), Positives = 93/238 (39%), Gaps = 21/238 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 ++GG + + + +A+ A+G CGG I W+LTA HC R +I+ + + Sbjct: 1 VIGGDECNINEHRF-LALVYANGSLCGGTLINQEWVLTARHCDRG----NMRIYLGMHNL 55 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + ++ N + DI LI + + P S+P+ P Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPS--- 112 Query: 460 LFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYD 515 C + GWG + ++ C Y CAG + Sbjct: 113 ---VGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG--LAATTLCAGILE 167 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 G D CKGDSGGPL+C G G C +P PG+YTKV +Y DWI + Sbjct: 168 GGKDTCKGDSGGPLICNGQFQGILSVG----GNPCAQPRKPGIYTKVFDYTDWIQSII 221 >1FON-A nrPDB Length = 240 Score = 206 bits (524), Expect = 2e-53, Method: Composition-based stats. Identities = 67/244 (27%), Positives = 106/244 (43%), Gaps = 19/244 (7%) Query: 342 GGKRAQLGDLPWQVAIKDAS----GITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 G+ A WQV+++ TCGG I W++TA HC+ S+T++ + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTY--QNDIALIEMKKDGNKKDCELPRSIPACVP 455 + + I I D + H +N+ NDIAL+++ + D A +P Sbjct: 61 SVLEGSEQVIPINAGD-LFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQL----ANLP 115 Query: 456 WSPYLFQPNDTCIVSGWGREKDNER-VFSLQWGEVKLIS--NCSKF-YGNRFYEKEMECA 511 + + C +SGWGR LQ + + +CS++ + +K M CA Sbjct: 116 PAGDILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCA 175 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE--NCGKPEFPGVYTKVANYFDWI 569 G C GDSGGPL C A+ V GV S+ C + P V+T+V+ + DWI Sbjct: 176 GGDT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWI 233 Query: 570 SYHV 573 + Sbjct: 234 DETI 237 >1GVZ-A nrPDB Length = 237 Score = 206 bits (524), Expect = 2e-53, Method: Composition-based stats. Identities = 68/252 (26%), Positives = 99/252 (39%), Gaps = 33/252 (13%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG + PWQVA+ CGG+ + W+LTAAHC+ + YQIW + Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCM----SDDYQIWLGRHNL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYN-----------AGTYQNDIALIEMKKDGNKKDCELPR 448 D V ++ +D+ L+ + + D Sbjct: 57 SK-DEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKIL 115 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISN--CSKFYGNRFY 504 +P P + TC SGWG N +LQ E++L SN C++ Y + Sbjct: 116 DLPTQEP------KLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMT 169 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVA 563 E + CA D S C GDSGG L+C G+ SWG C V+TKV Sbjct: 170 EF-VLCATHRDDSGSICLGDSGGALICDGV-----FQGITSWGYSECADFNDNFVFTKVM 223 Query: 564 NYFDWISYHVGR 575 + WI + + Sbjct: 224 PHKKWIKETIEK 235 >4X0L-C nrPDB Length = 259 Score = 206 bits (523), Expect = 3e-53, Method: Composition-based stats. Identities = 63/267 (23%), Positives = 105/267 (39%), Gaps = 30/267 (11%) Query: 326 SCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRAS 385 CG +RI+GG G PWQ + +T G I W+LT A L + Sbjct: 1 VCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLN 60 Query: 386 KTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCE 445 + K+ ++E +++++ H NY+ DI LI++K+ + + Sbjct: 61 HSENATAKDIAPTLTLYVGKKQLVE-IEKVVLHPNYSQV----DIGLIKLKQKVSVNE-- 113 Query: 446 LPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKL--ISNCSKFYGNRF 503 R +P C+P Y + VSGWGR + + L++ + + C + Y Sbjct: 114 --RVMPICLPSKDYA-EVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGST 170 Query: 504 YE----------------KEMECAGTYDGSIDACKGDSGGPLVCMD-ANNVTYVWGVVSW 546 + CAG D C GD+G D + Y G++S+ Sbjct: 171 VPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF 230 Query: 547 GENCGKPEFPGVYTKVANYFDWISYHV 573 ++C E GVY KV + DW+ + Sbjct: 231 DKSCAVAE-YGVYVKVTSIQDWVQKTI 256 >1AZZ-A nrPDB Length = 226 Score = 206 bits (523), Expect = 3e-53, Method: Composition-based stats. Identities = 66/241 (27%), Positives = 94/241 (39%), Gaps = 24/241 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG A P Q A+ CGG I WILTAAHC+ + + + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGA--GFVDVVLGAHNI 58 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + ++ I+ D HENYN+ NDIA+I + +P+ Sbjct: 59 REDEATQVTIQSTD-FTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPST------ 111 Query: 460 LFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 +GWG D+ L+ +V ++SN C YG C Sbjct: 112 DVGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG--IVTDGNICI-DST 168 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWG--ENCGKPEFPGVYTKVANYFDWISYHV 573 G C GDSGGPL N +G+ S+G C + +P +T+V + DWI Sbjct: 169 GGKGTCNGDSGGPL-----NYNGLTYGITSFGAAAGC-EAGYPDAFTRVTYFLDWIQTQT 222 Query: 574 G 574 G Sbjct: 223 G 223 >2XXL-A nrPDB Length = 408 Score = 206 bits (523), Expect = 3e-53, Method: Composition-based stats. Identities = 89/394 (22%), Positives = 144/394 (36%), Gaps = 62/394 (15%) Query: 203 TMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGK 262 +MG Q + Y +P D QC+ +C I + ++ + K Sbjct: 18 SMGVQ--SARADYADDCTTPDGDQGQCM------PFSSCRTIEERLTEAQKAGQKVPADY 69 Query: 263 GFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRIKSLL 322 + + +C ++ C + + Q +++++ D Sbjct: 70 ASYLQKALC--GEFNGVRHFCCPS-----------ANIQHNSKVMSLFKDE--------- 107 Query: 323 PKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDA----SGITCGGIYIGGCWILTA 378 CG + +R+ G +L PW ++ S CGG I +ILTA Sbjct: 108 -NFDCG-----NFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTA 161 Query: 379 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEY-----------VDRIIFHENYNAGTYQ 427 AHC+ + Y+I + R +++ + HE Y+A Sbjct: 162 AHCVHGLQNDLYEIRLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIM 221 Query: 428 NDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWG 487 +DIAL+++ + + P +P Q T V+GWG ++ L Sbjct: 222 HDIALLKLNRSVPFQKHIKPICLPITDELKEKAEQI-STYFVTGWGTTENGSSSDVLLQA 280 Query: 488 EVKLI--SNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYV----- 540 V L S CS+ Y R C G D D+CKGDSGGPL Y Sbjct: 281 NVPLQPRSACSQAYR-RAVPLSQLCVGGGDLQ-DSCKGDSGGPLQAPAQYLGEYAPKMVE 338 Query: 541 WGVVSWG-ENCGKPEFPGVYTKVANYFDWISYHV 573 +G+VS G CG+ PG+YT V Y WI+ + Sbjct: 339 FGIVSQGVVTCGQISLPGLYTNVGEYVQWITDTM 372 >4F4O-C nrPDB Length = 347 Score = 205 bits (522), Expect = 4e-53, Method: Composition-based stats. Identities = 79/357 (22%), Positives = 134/357 (37%), Gaps = 47/357 (13%) Query: 237 QMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIP-SQYQCNGEVDCITGEDEVGCAG 295 Q+ A + N+ D +D+ C K G +Y C T D V Sbjct: 15 QLFAAETGNEATDATDDSC-----PKPPEIPKGYVEHMVRYHCQTYYKLRTAGDGV---Y 66 Query: 296 FASVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQV 355 ++ T +T + ++ + CG + +RI+GG G PWQ Sbjct: 67 TLDSNKQWTNKVTGE------KLPEC--EAVCGKPKNPVDQVQRIMGGSLDAKGSFPWQA 118 Query: 356 AIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRI 415 + +T G I W+LT A LR + + K+ +E ++++ Sbjct: 119 KMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDIAPTLRLYVGKKQEVE-IEKV 177 Query: 416 IFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGRE 475 IFH + + DI LI++K+ + R +P C+P Y+ VSGWGR Sbjct: 178 IFHPDNSTV----DIGLIKLKQKVPVNE----RVMPICLPSKDYVN-VGLVGYVSGWGRN 228 Query: 476 KDNERVFSLQWGEVKLISN--CSKFYGNRFYE----------------KEMECAGTYDGS 517 + L++ + + C ++Y + CAG Sbjct: 229 ANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQ 288 Query: 518 IDACKGDSGGPLVCMD-ANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 D C GD+G D ++ Y G++S+ ++C E GVY +V + DWI + Sbjct: 289 EDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAE-YGVYVRVTSILDWIQTTI 344 >3I77-A nrPDB Length = 230 Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats. Identities = 69/238 (28%), Positives = 109/238 (45%), Gaps = 19/238 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDA-SGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 +VGG RA G+ P+ V + + + CGG +LTAAHC+ S + T V Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + V +++ + TY D ALI++ + N+ ++ + Sbjct: 61 DLQSSS--AVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTA------- 111 Query: 459 YLFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 514 T V+GWG RE +++ + L+ V +S+ C EM CAG Sbjct: 112 ---YNQGTFTVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSSSSFILVANEMICAGYP 167 Query: 515 D-GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 D G +D C+GDSGGP+ D + G+VSWG C +P +PGVYT+V+ + I+ Sbjct: 168 DTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGYGCARPGYPGVYTEVSTFASAIAS 225 >4Q7Y-A nrPDB Length = 250 Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats. Identities = 60/241 (24%), Positives = 96/241 (39%), Gaps = 15/241 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG P+ +++ CGG + W+++AAHC + Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH-V 59 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + +D + H +Y+ T+ NDI L+ + +P P Sbjct: 60 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPT 119 Query: 460 LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDG 516 C V+GWG D E + L +V+++ C+ + M C + D Sbjct: 120 ---AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDS 175 Query: 517 -SIDACKGDSGGPLVCMDANNVTYVWGVVSW-GENCGKPEFPGVYTKVANYFDWISYHVG 574 C DSGGPLVC + G+VS+ G CG P+ P VYT+V+ + WI V Sbjct: 176 HRRGFCSADSGGPLVCRNR-----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 230 Query: 575 R 575 R Sbjct: 231 R 231 >2ZKS-A nrPDB Length = 240 Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats. Identities = 62/245 (25%), Positives = 102/245 (41%), Gaps = 18/245 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG+ P+ +++ CGG+ + W+LTAAHCL A + + ++ + Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL-AQRMAQLRLVLGLHTL 59 Query: 400 IHPDLKRIVIEYVDRIIFHENYNA-GTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 P L ++ I H Y +ND+AL+++ P ++P+ Sbjct: 60 DSPGL----TFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPS----KR 111 Query: 459 YLFQPNDTCIVSGWGREKDNERVF-SLQWGEVKLISN--CSKF-YGNRFYEKEMECAGTY 514 + C ++GWG R+ L+ +++++ C+ + N M C Sbjct: 112 QVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAAD 171 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHV 573 CKGDSGGPLVC + GV+S+ C P V T VA Y WI Sbjct: 172 SKDQAPCKGDSGGPLVC---GKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVT 228 Query: 574 GRPFI 578 GR + Sbjct: 229 GRSAL 233 >2B9L-A nrPDB Length = 394 Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats. Identities = 74/277 (26%), Positives = 116/277 (41%), Gaps = 30/277 (10%) Query: 327 CGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDAS--------GITCGGIYIGGCWILTA 378 CG++N + K A+ G+ PW VA+ A+ + CGG I +LT Sbjct: 118 CGIRNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTG 177 Query: 379 AHCLRASKTHRYQIWTTVVDWIHPDLKRI---VIEYVDRIIFHENYNAGTYQNDIALIEM 435 AHC+ + +++ I +W K + ++I H N+N T ND+AL+ + Sbjct: 178 AHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLL 237 Query: 436 KKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNER---VFSLQWGEVKLI 492 + + D C+P +F C SGWG+++ R L+ ++ + Sbjct: 238 DRPLVQADNIGT----ICLPQQSQIFDS-TECFASGWGKKEFGSRHRYSNILKKIQLPTV 292 Query: 493 SN--CSKFYGNR------FYEKEMECAGTYDGSIDACKGDSGGPLVCMDANN--VTYVWG 542 C N ++ CAG G D C GD G PL C D N G Sbjct: 293 DRDKCQADLRNTRLGLKFVLDQTFVCAGGEQG-KDTCTGDGGSPLFCPDPRNPSRYMQMG 351 Query: 543 VVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFIS 579 +V+WG CG PGVY VA++ +WI + +S Sbjct: 352 IVAWGIGCGDENVPGVYANVAHFRNWIDQEMQAKGLS 388 >5LPF-A nrPDB Length = 234 Score = 202 bits (515), Expect = 3e-52, Method: Composition-based stats. Identities = 68/245 (27%), Positives = 103/245 (42%), Gaps = 32/245 (13%) Query: 343 GKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHP 402 G G PWQV++ + C G+ + W+LTAAHC +W V D Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC------GNKPLWARVGDDHLL 60 Query: 403 DLKRIVIEYVDRIIFHENYNAG--------TYQNDIALIEMKKDGNKKDCELPRSIPACV 454 L+ + R + H Y+ G T ++D+ L+++ + +P Sbjct: 61 LLQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRC 120 Query: 455 PWSPYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMEC 510 QP D C V+GWG ++ L + ++S C FY M C Sbjct: 121 A------QPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPG-VVTNNMIC 173 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWI 569 AG D D C+ DSGGPLVC + + G++SWG CG + P VYT++ Y WI Sbjct: 174 AG-LDRGQDPCQSDSGGPLVCDET-----LQGILSWGVYPCGSAQHPAVYTQICKYMSWI 227 Query: 570 SYHVG 574 + + Sbjct: 228 NKVIR 232 >4E7N-A nrPDB Length = 238 Score = 202 bits (513), Expect = 5e-52, Method: Composition-based stats. Identities = 64/243 (26%), Positives = 94/243 (38%), Gaps = 24/243 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG--ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 I+GG + + + VA+ + + CGG I W+LTAAHC K R ++ Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHC--DRKNFRIKLGMHSK 58 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 + D + V + ++ + N + DI LI + A Sbjct: 59 KVPNEDEQTRVPK--EKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHI------APFSLP 110 Query: 458 PYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFY--EKEMECA 511 C + GWGR E + + L+ C Y CA Sbjct: 111 SSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCA 170 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWIS 570 G +G D CKGDSGGPL+C G+ SWG + C +P P YTKV ++ DWI Sbjct: 171 GILEGGKDTCKGDSGGPLICNGQ-----FQGIASWGDDPCAQPHKPAAYTKVFDHLDWIE 225 Query: 571 YHV 573 + Sbjct: 226 NII 228 >1ORF-A nrPDB Length = 234 Score = 201 bits (511), Expect = 8e-52, Method: Composition-based stats. Identities = 61/244 (25%), Positives = 102/244 (41%), Gaps = 22/244 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG P+ V + C G I W+LTAAHC + R Q+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHSI 57 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + ++ V + + Y+ T + D+ L+++ + +P Sbjct: 58 TREEPTKQIML-VKKEFPYPCYDPATREGDLKLLQLTEKAKINKYV----TILHLPKKGD 112 Query: 460 LFQPNDTCIVSGWGREKDNER-VFSLQWGEV-----KLISNCSKFYGNRFYEKEMECAGT 513 +P C V+GWGR ++ +L+ E+ K+ ++ + + N M CAG+ Sbjct: 113 DVKPGTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGS 172 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG--ENCGKPEFPGVYTKVA-NYFDWIS 570 G D+C GDSG PL+C GV S+G CG P PGVY ++ + +WI Sbjct: 173 LRGGRDSCNGDSGSPLLCEGVFR-----GVTSFGLENKCGDPRGPGVYILLSKKHLNWII 227 Query: 571 YHVG 574 + Sbjct: 228 MTIK 231 >1PQ7-A nrPDB Length = 224 Score = 201 bits (510), Expect = 9e-52, Method: Composition-based stats. Identities = 65/237 (27%), Positives = 100/237 (42%), Gaps = 18/237 (7%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG A GD P+ V+I G CGG + +LTAAHC+ +QI + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + + H +Y+ ND+A++++ A + S Sbjct: 61 TSGG----ITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGY----ARLAASGS 110 Query: 460 LFQPNDTCIVSGWGREKDNE--RVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 + V+GWG + +L V ++S C YG +M CAG Sbjct: 111 DPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSS 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYH 572 G D+C+GDSGGP+V ++ + G VSWG C +P + GVY V +I + Sbjct: 171 GGKDSCQGDSGGPIV----DSSNTLIGAVSWGNGCARPNYSGVYASVGALRSFIDTY 223 >2RDL-A nrPDB Length = 226 Score = 200 bits (508), Expect = 2e-51, Method: Composition-based stats. Identities = 56/240 (23%), Positives = 100/240 (41%), Gaps = 21/240 (8%) Query: 340 IVGGKRAQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+GG + P+ ++ + C G I +++TAAHC S + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRS----ITVLLG 56 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + + +E V++ H Y+ NDI L+++K+ N ++P Sbjct: 57 AHNKKVKEDTWQKLE-VEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVG--TLPI--S 111 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERV-FSLQWGEVKLISNCSKFYGNRFYEKEMECAGTY 514 P C GWGR NE +LQ +++++ + + F+++ C G Sbjct: 112 AKSNSIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQEPQLCVGNP 171 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 + KGDSGGPL+C G+ S+ KP P V+T++++Y WI+ + Sbjct: 172 KKIRNVYKGDSGGPLLCAG-----IAQGIASYVLRNAKP--PSVFTRISHYRPWINKILR 224 >3BEU-A nrPDB Length = 224 Score = 199 bits (505), Expect = 4e-51, Method: Composition-based stats. Identities = 66/236 (27%), Positives = 102/236 (43%), Gaps = 21/236 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 +VGG RA G+ P+ V + CGG +LTAAHC+ S + T V Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + V +++ + TY D ALI++ + N+ ++ + Sbjct: 57 LQSSS--AVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTLKIATTTA-------- 106 Query: 460 LFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 T V+GWG RE +++ + L+ V +S+ C EM CAG Sbjct: 107 --YNQGTFTVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSSSSFILVANEMICAGYDT 163 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 D C+GDSGGP+ D + G+VSWGE C + GVYT+V+ + I+ Sbjct: 164 KQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGEGCARKGKYGVYTEVSTFASAIAS 219 >6BQM-A nrPDB Length = 506 Score = 198 bits (504), Expect = 5e-51, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 120/253 (47%), Gaps = 28/253 (11%) Query: 337 RKRIVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWT 394 RI+GG++A G+ P+ VA+ +++S + CGG Y+GG ++LTAAHC+ + + Sbjct: 8 SSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVLL 67 Query: 395 TVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPR-SIPAC 453 D D+ +V +I H +Y + NDIA++E+++D LPR S+ Sbjct: 68 GAFDM--NDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERD------PLPRRSVQIS 119 Query: 454 VPWSPYLFQPNDTCIVSGWGREKD-----NERVFSLQWGEVKLI---------SNCSKFY 499 + V G+G K+ ++ L +V + S+ Sbjct: 120 DSSDFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKN 179 Query: 500 GNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVY 559 CAG++ DAC GD+GGP + D+NN GVVSWG+ CG+ PGVY Sbjct: 180 NYSQLTNNAFCAGSF--GKDACSGDAGGP-IFFDSNNGRKQMGVVSWGDGCGRANSPGVY 236 Query: 560 TKVANYFDWISYH 572 T ++ + DW+ Sbjct: 237 TNLSVFNDWLDDQ 249 >2FMJ-A nrPDB Length = 222 Score = 197 bits (502), Expect = 9e-51, Method: Composition-based stats. Identities = 69/236 (29%), Positives = 105/236 (44%), Gaps = 23/236 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 +VGG RA G+ P+ V + CGG +LTAAHC+ S + T V Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + V +++ YN D ALI++ + N+ ++ + Sbjct: 57 LQSSS--AVKVRSTKVLQAPGYNGT--GKDWALIKLAQPINQPTLKIATTTA-------- 104 Query: 460 LFQPNDTCIVSGWG--REKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 515 T V+GWG RE +++ + L+ V +S+ C YGN E CAG Sbjct: 105 --YNQGTFTVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSAYGNELVANEEICAGYDT 161 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISY 571 G +D C+GDSGGP+ D + G+VSWGE C + GVYT+V+ + I+ Sbjct: 162 GGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGEGCARKGKYGVYTEVSTFASAIAS 217 >4LK4-A nrPDB Length = 357 Score = 196 bits (498), Expect = 3e-50, Method: Composition-based stats. Identities = 68/253 (26%), Positives = 102/253 (40%), Gaps = 27/253 (10%) Query: 337 RKRIVGGKRAQLGDLPWQVAIKDAS-----GITCGGIYIGGCWILTAAHCLRASKTHRYQ 391 RI+ G A + P VA+ G CGG ++GG ++LTAAHC + Sbjct: 8 SSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVD 67 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP 451 + D + + +I H +Y+ NDIA++E+ + + L Sbjct: 68 VIIGAYDLNNSSQGERI--AAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPAITLA---- 121 Query: 452 ACVPWSPYLFQPNDTCIVSGWGRE---KDNERVFSLQWGEVKLISN--CSKFYGNRFYEK 506 P + V+GWG K + LQ +V L+S C + Sbjct: 122 --GPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSD 179 Query: 507 ---EMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKV 562 CA D+C+GD+GGP+V G+VSWG E C K GVYT V Sbjct: 180 PNSTNFCAARLT--KDSCQGDAGGPIVVK---TGREQLGIVSWGDEQCAKTGTYGVYTNV 234 Query: 563 ANYFDWISYHVGR 575 + + DWI+ H + Sbjct: 235 SYFRDWITKHTNQ 247 >2HLC-A nrPDB Length = 230 Score = 194 bits (492), Expect = 1e-49, Method: Composition-based stats. Identities = 70/244 (28%), Positives = 105/244 (43%), Gaps = 20/244 (8%) Query: 340 IVGGKRAQLGDLPWQV----AIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTT 395 I+ G A G P+Q ++D + CGG I WILTAAHC+ + + + + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 396 VVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 V + + +RII H +N TY ND+ALI++ D P +P+ Sbjct: 61 V------QYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEE 113 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYD 515 + N VSGWG+ + + + V C++ Y + C G Sbjct: 114 LNNKF--ENIWATVSGWGQSNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTS 170 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSW--GENCGKPEFPGVYTKVANYFDWISYHV 573 C GDSGGP V D N + GVVS+ G C + P +++V +Y DWI + Sbjct: 171 DGKSPCFGDSGGPFVLSDKN---LLIGVVSFVSGAGC-ESGKPVGFSRVTSYMDWIQQNT 226 Query: 574 GRPF 577 G F Sbjct: 227 GIKF 230 >1EQ9-A nrPDB Length = 222 Score = 189 bits (479), Expect = 4e-48, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 103/240 (42%), Gaps = 22/240 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRA-SKTHRYQIWTTVVD 398 IVGGK A +G P+QV+++ + CG + +LTAAHC+ S +R ++ Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 + V+ + ++NY+ +ND+AL+ + D P + Sbjct: 61 LSESGD----VYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLE 116 Query: 459 YLFQPNDTCIVSGWGREK-DNERVFSLQWGEVKL--ISNCSKFYGNRFYEKEMECAGTYD 515 C ++GWG + +LQ E+ + C + R + C Sbjct: 117 SNP-----CTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERD-QWRVIDSH-ICT-LTK 168 Query: 516 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGR 575 AC GDSGGPLV A G+VS+G C P VYT+V+++ WI+ ++ + Sbjct: 169 RGEGACHGDSGGPLVANGA-----QIGIVSFGSPCAL-GEPDVYTRVSSFVSWINANLKK 222 >1AE5-A nrPDB Length = 225 Score = 188 bits (478), Expect = 5e-48, Method: Composition-based stats. Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 21/239 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG++A+ P+ +I++ CGG I +++TAA C ++ + D Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + + + + Y+ ND+ L+++ ++ N +P +P Sbjct: 61 RRRERQSRQTFSISSM-SENGYDPQQNLNDLMLLQLDREANLTSSV--TILP--LPLQNA 115 Query: 460 LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSI 518 + C V+GWG ++ R+ ++ V + C G Sbjct: 116 TVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVT-------PEDQCRPNNVCTGVLTRRG 168 Query: 519 DACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHVGRP 576 C GD G PLVC GV S+ CG+ P +T+VA + DWI + P Sbjct: 169 GICNGDGGTPLVCEG-----LAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLNNP 220 >2ASU-B nrPDB Length = 234 Score = 184 bits (468), Expect = 7e-47, Method: Composition-based stats. Identities = 61/243 (25%), Positives = 104/243 (42%), Gaps = 21/243 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG-ITCGGIYIGGCWILTAAHCLRASKTHR--YQIWTTV 396 +VGG G+ PW V++++ G CGG + WILTA C + Y++W Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 397 V-DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVP 455 + + V +++ G + + L+++++ R C+P Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVC------GPSGSQLVLLKLERSVTLNQ----RVALICLP 107 Query: 456 WSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT 513 Y+ P C ++GWG K L + +ISN C+ + R E EM C Sbjct: 108 PEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEM-CTEG 166 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 + AC+GD GGPL C N+ + G++ C + +P V+T+V+ + DWI + Sbjct: 167 LLAPVGACEGDYGGPLACFTHNS-WVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVM 225 Query: 574 GRP 576 Sbjct: 226 RLG 228 >1PPF-E nrPDB Length = 218 Score = 184 bits (466), Expect = 1e-46, Method: Composition-based stats. Identities = 53/236 (22%), Positives = 91/236 (38%), Gaps = 21/236 (8%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 IVGG+RA+ P+ V+++ G CG I ++++AAHC+ ++ + Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + R V + IF Y+ NDI ++++ A +P Sbjct: 61 SRREPTRQVF--AVQRIFENGYDPVNLLNDIVILQLNGSATINANVQV----AQLPAQGR 114 Query: 460 LFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSI 518 C+ GWG N + S LQ V ++++ + + C Sbjct: 115 RLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCR--------RSNVCTLVRGRQA 166 Query: 519 DACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHV 573 C GDSG PLVC + G+ S+ C +P + VA + +WI + Sbjct: 167 GVCFGDSGSPLVCNG-----LIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 217 >1SI5-H nrPDB Length = 240 Score = 183 bits (465), Expect = 2e-46, Method: Composition-based stats. Identities = 61/240 (25%), Positives = 100/240 (41%), Gaps = 20/240 (8%) Query: 340 IVGG--KRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 +V G R +G W V+++ + CGG I W+LTA C + Y+ W + Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 398 DWI-HPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPW 456 D D K + V ++++ G +D+ L+++ + D +P Sbjct: 58 DVHGRGDEKCKQVLNVSQLVY------GPEGSDLVLMKLARPAVLDDFVSTIDLPNY--- 108 Query: 457 SPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEM-ECAGT 513 +C V GWG L+ + ++ N CS+ + + E CAG Sbjct: 109 -GSTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGA 167 Query: 514 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 C+GD GGPLVC + + + V GV+ G C P PG++ +VA Y WI + Sbjct: 168 EKIGSGPCEGDYGGPLVC-EQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >5XRF-A nrPDB Length = 242 Score = 182 bits (462), Expect = 3e-46, Method: Composition-based stats. Identities = 62/244 (25%), Positives = 90/244 (36%), Gaps = 28/244 (11%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 ++GG + + A C G I W+L AAHC + + Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGL--NIYLGMHNQ 64 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 D +R R E+Y Y+ D L + +KD P S + Sbjct: 65 SIQFDDEQR-------RYAIEEHY----YRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPL 113 Query: 458 PYLFQP---NDTCIVSGWGREKDNE--RVFSLQWGEVKLIS--NCSKFYGNRFYEKEMEC 510 P C V GWG + + L++ C Y + + C Sbjct: 114 SLPSSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLC 173 Query: 511 AGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWG-ENCGKPEFPGVYTKVANYFDWI 569 AG +G ID C DSGGPL+C G+V +G C +P PG+YT+V+NY DWI Sbjct: 174 AGVLEGGIDTCNQDSGGPLICDGQ-----FQGIVFFGKYPCAQPNKPGLYTRVSNYNDWI 228 Query: 570 SYHV 573 + Sbjct: 229 QNII 232 >1M9U-A nrPDB Length = 241 Score = 180 bits (457), Expect = 1e-45, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 108/248 (43%), Gaps = 23/248 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG---ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTV 396 ++GG A G+ PWQ++ + SG +CG + L+A+HC+ + ++ + Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 397 VDWIHPDLKRIVIEYVDRIIFHENYNAGT--YQNDIALIEMKKDGNKKDCELPRSIPACV 454 W D VD HENY AGT Y NDIA++ + + +PA Sbjct: 61 --WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPA-- 116 Query: 455 PWSPYLFQPNDTCIVSGWGRE-KDNERVFSLQWGEVKLIS--NCSKF---YGNRFYEKEM 508 + TC++SGWGR N LQ + +I+ C+ G Sbjct: 117 --NNNNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNH 174 Query: 509 ECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSW----GENCGKPEFPGVYTKVAN 564 C G+ AC GDSGGPL C D T V GV SW G P++P VYT+V+ Sbjct: 175 ICVQDPAGNTGACNGDSGGPLNCPD--GGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSA 232 Query: 565 YFDWISYH 572 Y WI + Sbjct: 233 YLGWIGDN 240 >3H7O-A nrPDB Length = 228 Score = 154 bits (388), Expect = 1e-37, Method: Composition-based stats. Identities = 60/242 (24%), Positives = 106/242 (43%), Gaps = 22/242 (9%) Query: 342 GGKRAQLGDLPWQVAIKD---ASGITCGGIYIGGCWILTAAHCLRASKTHRYQI-WTTVV 397 GG++ + +PW VA++ +TCGG + ++LTAAHC+ K I + + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 457 W P + +V Y T +NDIA++E+ + +S PA +P Sbjct: 62 LWEDPGKSDPYVSHVYLSF----YRQETMENDIAILELSRPLKLDGL---KSKPAKLPDI 114 Query: 458 PYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLI--SNCSKFYGNRFYEKEMECAGTY 514 + + +VSG+G + + L+ ++ ++ C YG F ++ CA Sbjct: 115 EFRPKTGSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKV 174 Query: 515 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 S+++ GD+G P V D + GV ++ P V+TKV +Y WI + Sbjct: 175 GVSLES--GDAGDPTVQQDT-----LVGVAAYFPK-RPEGAPEVFTKVGSYVSWIQDIIK 226 Query: 575 RP 576 + Sbjct: 227 KK 228 >5ZE3-A nrPDB Length = 457 Score = 153 bits (386), Expect = 2e-37, Method: Composition-based stats. Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 114 VSLKHGNTDSEGIVEVKLVDQDKTM---FICKSSWSMREANVAC--LDLGFQQGADTQRR 168 + L G EG VEV LV++ ++ +C +W + EA V C L LGF A + Sbjct: 118 LRLNGGRNPYEGRVEV-LVERQGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETW 176 Query: 169 FKLSDLSINSTECLHVHCRGLETSLAECTFTKRRTM----GYQDFADVVCYTQKAD 220 + D++ N V C G E SLA C G Q A V C D Sbjct: 177 YWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPD 232 Score = 51.2 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 4/106 (3%) Query: 114 VSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSD 173 V L+ G EG VEV + T +C W + A+V C +LGF + +L Sbjct: 9 VRLRGGAYIGEGRVEVLKNGEWGT--VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQ 66 Query: 174 LSINSTECLHVHCRGLETSLAECTFTKR-RTMGYQDFADVVCYTQK 218 I + C G E S+ +C F + +++ A V C T Sbjct: 67 -GIGPIHLNEIQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPA 111 >2PKA-B nrPDB Length = 152 Score = 151 bits (381), Expect = 9e-37, Method: Composition-based stats. Identities = 46/159 (28%), Positives = 68/159 (42%), Gaps = 19/159 (11%) Query: 422 NAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN--- 478 + Y +D+ L+ ++ D +P P TC SGWG + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPEL------GSTCEASGWGSIEPGPDD 55 Query: 479 -ERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDAN 535 E +Q ++ L+ N C+ + ++ + M CAG G D C GDSGGPL+C Sbjct: 56 FEFPDEIQCVQLTLLQNTFCADAHPDKV-TESMLCAGYLPGGKDTCMGDSGGPLICNG-- 112 Query: 536 NVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWISYHV 573 G+ SWG CG P +YTK+ Y DWI + Sbjct: 113 ---MWQGITSWGHTPCGSANKPSIYTKLIFYLDWIDDTI 148 >3H7T-A nrPDB Length = 235 Score = 148 bits (374), Expect = 5e-36, Method: Composition-based stats. Identities = 54/235 (22%), Positives = 91/235 (38%), Gaps = 22/235 (9%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GGK++ + PW V + CGG + +++TAA C+ +K I Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS--- 57 Query: 400 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 459 + +I Y+ T QN+ A+IE + D + +P Y Sbjct: 58 -SYRTTKGTSVMAKKIYI-VRYHPLTMQNNYAVIETEMPIKLDDK---TTKKIELPSLLY 112 Query: 460 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYG----NRFYEKEMECA 511 +P+ + +VSGWG +S L ++ C + Y +++ + CA Sbjct: 113 DPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCA 172 Query: 512 GTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYF 566 G GD+G P V + GV S+ + EFP V+ +V Y Sbjct: 173 GGEYDETYIGYGDAGDPAVQNGT-----LVGVASYISSM-PSEFPSVFLRVGYYV 221 >5XW8-A nrPDB Length = 133 Score = 143 bits (360), Expect = 2e-34, Method: Composition-based stats. Identities = 38/145 (26%), Positives = 60/145 (41%), Gaps = 12/145 (8%) Query: 332 RMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQ 391 +IVGG +P+QV++ ++ CGG I W+++AAHC ++ R Q Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKS----RIQ 55 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIP 451 + + + I +II H N+N T NDI LI++ S+P Sbjct: 56 VRLGEHNIDVLEGNEQFI-NAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLP 114 Query: 452 ACVPWSPYLFQPNDTCIVSGWGREK 476 C++SGWG K Sbjct: 115 ------RSCAAAGTECLISGWGNTK 133 >1RIW-B nrPDB Length = 147 Score = 141 bits (355), Expect = 1e-33, Method: Composition-based stats. Identities = 42/148 (28%), Positives = 60/148 (40%), Gaps = 10/148 (6%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASK------THRYQ 391 IV G A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSI 450 + + I +++I H YN DIAL+++KK D P + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDN 478 P + L Q V+GWG K+ Sbjct: 121 PD-RETAASLLQAGYKGRVTGWGNLKET 147 >3VGC-B nrPDB Length = 131 Score = 139 bits (351), Expect = 3e-33, Method: Composition-based stats. Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 9/137 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDASG-ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 398 IV G+ A G PWQV+++D +G CGG I W++TAAHC T + D Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC---GVTTSDVVVAGEFD 57 Query: 399 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 458 ++I + ++ + YN+ T NDI L+++ + C+P + Sbjct: 58 QGSSS-EKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAV----CLPSAS 112 Query: 459 YLFQPNDTCIVSGWGRE 475 F TC+ +GWG Sbjct: 113 DDFAAGTTCVTTGWGLT 129 >2JET-B nrPDB Length = 128 Score = 138 bits (347), Expect = 8e-33, Method: Composition-based stats. Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 9/135 (6%) Query: 343 GKRAQLGDLPWQVAIKDASG-ITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIH 401 G+ A G PWQV+++D +G CGG I W++TAAHC + D Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC---GVKTSDVVVAGEFD-QG 56 Query: 402 PDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLF 461 D + I + + ++ + +N T +NDI L+++ + C+P F Sbjct: 57 SDEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAV----CLPNVDDDF 112 Query: 462 QPNDTCIVSGWGREK 476 P C +GWG+ K Sbjct: 113 PPGTVCATTGWGKTK 127 >1BBR-H nrPDB Length = 150 Score = 137 bits (344), Expect = 2e-32, Method: Composition-based stats. Identities = 41/148 (27%), Positives = 61/148 (41%), Gaps = 10/148 (6%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHR------YQ 391 IV G+ A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 392 IWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSI 450 + + K I +D+I H YN DIAL+++K+ D P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 451 PACVPWSPYLFQPNDTCIVSGWGREKDN 478 P + L V+GWG ++ Sbjct: 121 PDK-QTAAKLLHAGFKGRVTGWGNRRET 147 >2WIN-I nrPDB Length = 507 Score = 133 bits (335), Expect = 2e-31, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 75/250 (30%), Gaps = 65/250 (26%) Query: 346 AQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLR-ASKTHRYQIWTTVVDWI 400 PWQ I +C G + ++LTAAHC K H ++ Sbjct: 229 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRD 288 Query: 401 HPDLKRIVIEYVDRIIFHENYN---------AGTYQNDIALIEMKKDGNKKDCELPRSIP 451 ++ ++FH NYN Y D+ALI++K P +P Sbjct: 289 LE---------IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLP 339 Query: 452 ACVPWSPYL-FQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNR-------- 502 + L P TC + E + Q + +S K + Sbjct: 340 CTEGTTRALRLPPTTTCQ-------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGD 392 Query: 503 -----------------------FYEKEMECAGTYDGSID--ACKGDSGGPLVCMDANNV 537 C G D C+GDSGGPL+ + Sbjct: 393 KKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHK-RSR 451 Query: 538 TYVWGVVSWG 547 GV+SWG Sbjct: 452 FIQVGVISWG 461 >2I6S-A nrPDB Length = 517 Score = 130 bits (326), Expect = 2e-30, Method: Composition-based stats. Identities = 61/286 (21%), Positives = 101/286 (35%), Gaps = 58/286 (20%) Query: 341 VGGKRAQLGDL---PWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 397 VG A D PW V IK S TC G I W+LTAAHC R H V Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLW----RV 285 Query: 398 DWIHPDLKRIVIEYVDRIIFHENYNA---------GTYQNDIALIEMKKDGNKKDCELPR 448 + P + +++ + ++ Y +DIAL+++ + P Sbjct: 286 NVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPI 345 Query: 449 SIPACVPWSPYLFQP-NDTCI----------------VSGWGREKDNERVFSLQWGE-VK 490 +P + + L +P TC V+ G + + ++W + Sbjct: 346 CLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAE 405 Query: 491 LISNCSKFYGN-----RFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVS 545 ++S + N + C+GT + CKG+SGG V ++ + G+VS Sbjct: 406 VVSQEKTMFPNLTDVREVVTDQFLCSGTQEDE-SPCKGESGGA-VFLERRFRFFQVGLVS 463 Query: 546 WG--ENC-------GKPEFP--------GVYTKVANYFDWISYHVG 574 WG C + P + + W+ H+G Sbjct: 464 WGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLG 509 >1DLE-A nrPDB Length = 298 Score = 128 bits (321), Expect = 8e-30, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 75/250 (30%), Gaps = 65/250 (26%) Query: 346 AQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLR-ASKTHRYQIWTTVVDWI 400 PWQ I +C G + ++LTAAHC K H ++ Sbjct: 22 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRD 81 Query: 401 HPDLKRIVIEYVDRIIFHENYN---------AGTYQNDIALIEMKKDGNKKDCELPRSIP 451 ++ ++FH NYN Y D+ALI++K P +P Sbjct: 82 LE---------IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLP 132 Query: 452 ACVPWSPYL-FQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNR-------- 502 + L P TC + E + Q + +S K + Sbjct: 133 CTEGTTRALRLPPTTTCQ-------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGD 185 Query: 503 -----------------------FYEKEMECAGTYDGSID--ACKGDSGGPLVCMDANNV 537 C G D C+GDSGGPL+ + Sbjct: 186 KKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHK-RSR 244 Query: 538 TYVWGVVSWG 547 GV+SWG Sbjct: 245 FIQVGVISWG 254 >2OK5-A nrPDB Length = 752 Score = 127 bits (320), Expect = 1e-29, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 75/250 (30%), Gaps = 65/250 (26%) Query: 346 AQLGDLPWQVAIK----DASGITCGGIYIGGCWILTAAHCLR-ASKTHRYQIWTTVVDWI 400 PWQ I +C G + ++LTAAHC K H ++ Sbjct: 473 TDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRD 532 Query: 401 HPDLKRIVIEYVDRIIFHENYN---------AGTYQNDIALIEMKKDGNKKDCELPRSIP 451 ++ ++FH NYN Y D+ALI++K P +P Sbjct: 533 LE---------IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLP 583 Query: 452 ACVPWSPYL-FQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNR-------- 502 + L P TC + E + Q + +S K + Sbjct: 584 CTEGTTRALRLPPTTTCQ-------QQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGD 636 Query: 503 -----------------------FYEKEMECAGTYDGSID--ACKGDSGGPLVCMDANNV 537 C G D C+GDSGGPL+ + Sbjct: 637 KKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHK-RSR 695 Query: 538 TYVWGVVSWG 547 GV+SWG Sbjct: 696 FIQVGVISWG 705 >1AKS-B nrPDB Length = 98 Score = 120 bits (300), Expect = 2e-27, Method: Composition-based stats. Identities = 37/100 (37%), Positives = 50/100 (50%), Gaps = 8/100 (8%) Query: 476 KDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMD 533 + LQ + ++SN C Y + M C G G D+C+GDSGGP+VC Sbjct: 2 SGSSYPSLLQCLKAPVLSNSSCKSSYPGQI-TGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 534 ANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 + G+VSWG C + PGVYTKV NY +WI + Sbjct: 61 Q-----LQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTI 95 >3M0C-C nrPDB Length = 791 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 34/81 (41%), Positives = 40/81 (49%), Gaps = 3/81 (3%) Query: 217 QKADSPMDDF-FQCVNGKYISQMKACDGINDCGDQSDELCCK--ACQGKGFHCKSGVCIP 273 Q SP F F C++G+ I CDG DC D+SDE C C+ F C G CI Sbjct: 188 QGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIH 247 Query: 274 SQYQCNGEVDCITGEDEVGCA 294 QC+ E DC DEVGC Sbjct: 248 GSRQCDREYDCKDMSDEVGCV 268 Score = 73.2 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 32/91 (35%), Positives = 41/91 (45%), Gaps = 4/91 (4%) Query: 207 QDFADVVCYTQKADSPMDDFFQC--VNGKYISQMKACDGINDCGDQSDELCC--KACQGK 262 QD +D T + + F C + I Q CDG DC + SDE C K C Sbjct: 50 QDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQD 109 Query: 263 GFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 F C G CI Q+ C+ + DC+ G DE C Sbjct: 110 EFRCHDGKCISRQFVCDSDRDCLDGSDEASC 140 Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 16/123 (13%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDELCCK----ACQGKGFHC--KSGVCIPSQYQCNG 280 FQC +GK IS CDG +C D SDE C+ F C + CIP ++C+G Sbjct: 29 FQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDG 88 Query: 281 EVDCITGEDEVGCAGFASVTQE----------ETEILTADMDAERRRIKSLLPKLSCGVK 330 +VDC G DE GC E + +D D ++ P L+CG Sbjct: 89 QVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPA 148 Query: 331 NRM 333 + Sbjct: 149 SFQ 151 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 259 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDE 290 C+ F C+ G CI ++ C+G +C G DE Sbjct: 24 CERNEFQCQDGKCISYKWVCDGSAECQDGSDE 55 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 30/119 (25%), Positives = 42/119 (35%), Gaps = 8/119 (6%) Query: 176 INSTECLHVHCRGLET--SLAECTFTKR---RTMGYQDFADVVCYTQKADSPMDDFFQCV 230 + C CR E S C R R +D +D V + F+C Sbjct: 223 SDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCH 282 Query: 231 NGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIP--SQYQCNGEVDCITG 287 +G+ I+ K C+ DC D SDE K C +G C + + E C G Sbjct: 283 SGECITLDKVCNMARDCRDWSDEP-IKECGTNECLDNNGGCSHVCNDLKIGYECLCPDG 340 >1N7D-A nrPDB Length = 699 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 34/81 (41%), Positives = 40/81 (49%), Gaps = 3/81 (3%) Query: 217 QKADSPMDDF-FQCVNGKYISQMKACDGINDCGDQSDELCCK--ACQGKGFHCKSGVCIP 273 Q SP F F C++G+ I CDG DC D+SDE C C+ F C G CI Sbjct: 170 QGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIH 229 Query: 274 SQYQCNGEVDCITGEDEVGCA 294 QC+ E DC DEVGC Sbjct: 230 GSRQCDREYDCKDMSDEVGCV 250 Score = 72.4 bits (176), Expect = 5e-13, Method: Composition-based stats. Identities = 32/91 (35%), Positives = 41/91 (45%), Gaps = 4/91 (4%) Query: 207 QDFADVVCYTQKADSPMDDFFQC--VNGKYISQMKACDGINDCGDQSDELCC--KACQGK 262 QD +D T + + F C + I Q CDG DC + SDE C K C Sbjct: 32 QDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQD 91 Query: 263 GFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 F C G CI Q+ C+ + DC+ G DE C Sbjct: 92 EFRCHDGKCISRQFVCDSDRDCLDGSDEASC 122 Score = 66.2 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 6/82 (7%) Query: 227 FQCVNGKYISQMKACDGINDCGDQSDELCCK----ACQGKGFHC--KSGVCIPSQYQCNG 280 FQC +GK IS CDG +C D SDE C+ F C + CIP ++C+G Sbjct: 11 FQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDG 70 Query: 281 EVDCITGEDEVGCAGFASVTQE 302 +VDC G DE GC E Sbjct: 71 QVDCDNGSDEQGCPPKTCSQDE 92 Score = 40.0 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%) Query: 259 CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDE 290 C+ F C+ G CI ++ C+G +C G DE Sbjct: 6 CERNEFQCQDGKCISYKWVCDGSAECQDGSDE 37 Score = 33.9 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 41/119 (34%), Gaps = 6/119 (5%) Query: 176 INSTECLHVHCRGLET--SLAECTFTKR---RTMGYQDFADVVCYTQKADSPMDDFFQCV 230 + C CR E S C R R +D +D V + F+C Sbjct: 205 SDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCH 264 Query: 231 NGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGED 289 +G+ I+ K C+ DC D SDE K C +G C +C+ + Sbjct: 265 SGECITLDKVCNMARDCRDWSDEP-IKECGTNECLDNNGGCSHVCNDLKIGYECLCPDG 322 >1BBR-E nrPDB Length = 109 Score = 113 bits (283), Expect = 2e-25, Method: Composition-based stats. Identities = 37/102 (36%), Positives = 44/102 (43%), Gaps = 7/102 (6%) Query: 480 RVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSI---DACKGDSGGPLVCMDA 534 + LQ + L+ C R M CAG G DAC+GDSGGP V Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRI-TDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSP 64 Query: 535 -NNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGR 575 NN Y G+VSWGE C + G YT V WI + R Sbjct: 65 YNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2HNT-F nrPDB Length = 105 Score = 111 bits (277), Expect = 9e-25, Method: Composition-based stats. Identities = 34/103 (33%), Positives = 43/103 (41%), Gaps = 7/103 (6%) Query: 479 ERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGT---YDGSIDACKGDSGGPLVCMD 533 + LQ + ++ C R M CAG DAC+GDSGGP V Sbjct: 1 GQPSVLQVVNLPIVERPVCKDSTRIRI-TDNMFCAGYKPDEGKRGDACEGDSGGPFVMKS 59 Query: 534 A-NNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGR 575 NN Y G+VSWGE C + G YT V WI + + Sbjct: 60 PFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 102 >5B4X-B nrPDB Length = 570 Score = 108 bits (269), Expect = 8e-24, Method: Composition-based stats. Identities = 29/68 (42%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Query: 225 DFFQCVNGKYISQMKACDGINDCGDQSDELCC--KACQGKGFHCKSGVCIPSQYQCNGEV 282 D FQC N + I + CD +DC D SDE C K C F C +G CI +++C+GE Sbjct: 10 DQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEE 69 Query: 283 DCITGEDE 290 +C G DE Sbjct: 70 ECPDGSDE 77 Score = 82.4 bits (202), Expect = 5e-16, Method: Composition-based stats. Identities = 35/94 (37%), Positives = 47/94 (50%), Gaps = 10/94 (10%) Query: 211 DVVCYTQKADSP----MDDFFQCVNGKYISQMKACDGINDCGDQSDEL---CCK-ACQGK 262 D + ++ + D P D F C NG I + CDG +C D SDE C K C + Sbjct: 31 DCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAE 90 Query: 263 GFHC--KSGVCIPSQYQCNGEVDCITGEDEVGCA 294 C S C+P+ ++C+GE DC G DE GCA Sbjct: 91 KLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCA 124 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 11/110 (10%) Query: 194 AECTFTKRRTMGYQDFADVVCYT----QKADSPMDDFFQC--VNGKYISQMKACDGINDC 247 C + + G ++ D + K P + C + K + CDG DC Sbjct: 56 GHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEK-LSCGPTSHKCVPASWRCDGEKDC 114 Query: 248 GDQSDELCCKA----CQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 +DE C C+G F C G C+ + CN E DC G DE GC Sbjct: 115 EGGADEAGCATSLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 164 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 22/37 (59%) Query: 257 KACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 K C+ F C++ CIPS ++C+ + DC+ DE C Sbjct: 5 KECEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDC 41 >3RU4-E nrPDB Length = 96 Score = 101 bits (251), Expect = 1e-21, Method: Composition-based stats. Identities = 34/97 (35%), Positives = 49/97 (50%), Gaps = 6/97 (6%) Query: 479 ERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANN 536 LQ + L+SN C K++G + + M CAG + +C GDSGGPLVC N Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKI-KDAMICAGAS--GVSSCMGDSGGPLVCKK-NG 56 Query: 537 VTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 + G+VSWG + PGVY +V +W+ + Sbjct: 57 AWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTL 93 >2JET-C nrPDB Length = 99 Score = 99.0 bits (245), Expect = 5e-21, Method: Composition-based stats. Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 6/97 (6%) Query: 479 ERVFSLQWGEVKLIS--NCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANN 536 + LQ + ++S +C K +G++ M CAG +D+C GDSGGPLVC + Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKI-TDVMTCAGAS--GVDSCMGDSGGPLVCQK-DG 59 Query: 537 VTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHV 573 V + G+VSWG PGVY++V W+ + Sbjct: 60 VWTLAGIVSWGSGVCSTSTPGVYSRVTALMPWVQQIL 96 >2KAI-A nrPDB Length = 80 Score = 97.4 bits (241), Expect = 1e-20, Method: Composition-based stats. Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 5/83 (6%) Query: 340 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 399 I+GG+ + PWQVAI S CGG+ + W+LTAAHC K Y++W + Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHC----KNDNYEVWLGRHNL 56 Query: 400 IHPDLKRIVIEYVDRIIFHENYN 422 + V H +N Sbjct: 57 FENE-NTAQFFGVTADFPHPGFN 78 >3F1S-B nrPDB Length = 283 Score = 94.7 bits (234), Expect = 1e-19, Method: Composition-based stats. Identities = 68/286 (23%), Positives = 103/286 (36%), Gaps = 24/286 (8%) Query: 292 GCAGFASVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDL 351 GC F QE A K +P C +R L DL Sbjct: 12 GCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSEKRA-------PDLQDL 64 Query: 352 PWQVAIKDASGI-TCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIE 410 PWQV + ++ G CGG+ I ++LT A C S HR T + D I I Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC---SLLHRNITVKTYFNRTSQDPLMIKIT 121 Query: 411 YVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVS 470 +V H Y+A +ND++L+E++ LP P ++ +L P ++S Sbjct: 122 HVH---VHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKD-FAEHLLIPRTRGLLS 177 Query: 471 GWGREKDNERVFSLQWGEVKLI--SNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGP 528 GW R + SL V L+ C + + + S A G Sbjct: 178 GWAR-NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRT-----YCERSSVAAMHWMDGS 231 Query: 529 LVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVG 574 +V + ++ GV+ G+ V TKV+ Y W + Sbjct: 232 VVTREHRGSWFLTGVLGSQPVGGQAHMVLV-TKVSRYSLWFKQIMN 276 >3H5C-B nrPDB Length = 317 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 76/324 (23%), Positives = 114/324 (35%), Gaps = 31/324 (9%) Query: 258 ACQGK--GFHCKSGVCIPS--QYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDA 313 +CQ G+ C C P C + E GC F QE A Sbjct: 18 SCQDSIWGYTC---TCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYR 74 Query: 314 ERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGI-TCGGIYIGG 372 K +P C +R L DLPWQV + ++ G CGG+ I Sbjct: 75 LGEDHKQCVPHDQCACGVLTSEKRA-------PDLQDLPWQVKLTNSEGKDFCGGVIIRE 127 Query: 373 CWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIAL 432 ++LT A C S HR T + D I I +V H Y+A +ND++L Sbjct: 128 NFVLTTAKC---SLLHRNITVKTYFNRTSQDPLMIKITHVH---VHMRYDADAGENDLSL 181 Query: 433 IEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLI 492 +E++ LP P ++ +L P ++SGW R + SL V L+ Sbjct: 182 LELEWPIQCPGAGLPVCTPEKD-FAEHLLIPRTRGLLSGWAR-NGTDLGNSLTTRPVTLV 239 Query: 493 --SNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENC 550 C + + + S A G +V + ++ GV+ Sbjct: 240 EGEECGQVLNVTVTTRT-----YCERSSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVG 294 Query: 551 GKPEFPGVYTKVANYFDWISYHVG 574 G+ V TKV+ Y W + Sbjct: 295 GQAHMVLV-TKVSRYSLWFKQIMN 317 >1EPT-B nrPDB Length = 82 Score = 83.6 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 32/88 (36%), Gaps = 7/88 (7%) Query: 389 RYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPR 448 R Q+ + + I +II H N+N T NDI LI++ Sbjct: 2 RIQVRLGEHNIDVLEGNEQFI-NAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 449 SIPACVPWSPYLFQPNDTCIVSGWGREK 476 S+P C++SGWG K Sbjct: 61 SLP------RSCAAAGTECLISGWGNTK 82 >2HNT-E nrPDB Length = 81 Score = 77.4 bits (189), Expect = 1e-14, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 2/73 (2%) Query: 407 IVIEYVDRIIFHENYN-AGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPND 465 I +++I H YN DIAL+++KK D P +P + L Q Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPD-RETAASLLQAGY 61 Query: 466 TCIVSGWGREKDN 478 V+GWG K+ Sbjct: 62 KGRVTGWGNLKET 74 >2HNT-C nrPDB Length = 70 Score = 69.3 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Query: 340 IVGGKRAQLGDLPWQVAI--KDASGITCGGIYIGGCWILTAAHCLRASKTHR 389 IV G A++G PWQV + K + CG I W+LTAAHCL + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDK 52 >2J8L-A nrPDB Length = 90 Score = 68.9 bits (167), Expect = 5e-12, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 28/83 (33%), Gaps = 15/83 (18%) Query: 250 QSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTA 309 +S E C K C C+ P+Q CN E + C S T+IL Sbjct: 23 KSHEACQKLCTN-AVRCQFFTYTPAQASCN--------EGKGKCYLKLSSNGSPTKILHG 73 Query: 310 DMDAERRRIKSLLPKLSCGVKNR 332 R I +L C + N Sbjct: 74 -----RGGISGYTLRL-CKMDNE 90 >6H03-G nrPDB Length = 538 Score = 52.4 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 214 CYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKA 258 C + D D FQC G+ I C+G NDCGD SDE C++ Sbjct: 73 CEDAEDDCGND--FQCSTGRCIKMRLRCNGDNDCGDFSDEDDCES 115 Score = 42.7 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 13/61 (21%) Query: 233 KYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVG 292 + + D +DCG+ F C +G CI + +CNG+ DC DE Sbjct: 66 QCVPTEPCEDAEDDCGN-------------DFQCSTGRCIKMRLRCNGDNDCGDFSDEDD 112 Query: 293 C 293 C Sbjct: 113 C 113 >6CXO-A nrPDB Length = 529 Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 3/67 (4%) Query: 193 LAECTFTKR---RTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGD 249 LA F + +G + + ++ + FQC G+ I + C+G NDCGD Sbjct: 47 LAFGQFNGKSCVDVLGDRQGCEPTQECEEIQENCGNDFQCETGRCIKRRLLCNGDNDCGD 106 Query: 250 QSDELCC 256 SDE C Sbjct: 107 YSDENDC 113 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 6/53 (11%) Query: 241 CDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 C+ +C E + C G F C++G CI + CNG+ DC DE C Sbjct: 67 CEPTQEC-----EEIQENC-GNDFQCETGRCIKRRLLCNGDNDCGDYSDENDC 113 >5H7V-A nrPDB Length = 421 Score = 47.7 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 30/77 (38%), Gaps = 2/77 (2%) Query: 230 VNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGED 289 + I + G + ++ +C CQ F C +G CI S +C+ +C D Sbjct: 262 REEECILACRGVQGPS--MERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASD 319 Query: 290 EVGCAGFASVTQEETEI 306 E C + S E I Sbjct: 320 EAACEKYTSGFDELQRI 336 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 40/120 (33%), Gaps = 25/120 (20%) Query: 226 FFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGK-------GFHCKSGVCIP----- 273 F+C NG I CD +C D SDE C+ F G C+ Sbjct: 293 QFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTG 352 Query: 274 ------SQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTA-------DMDAERRRIKS 320 ++ N + GC G + +EE + L + D+ RR I + Sbjct: 353 LCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPT 412 >3OJY-A nrPDB Length = 554 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 36/100 (36%), Gaps = 2/100 (2%) Query: 223 MDDFFQCV-NGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGE 281 FQC G+ + + C+G DC D SDE C+ + C IP + Sbjct: 66 CGQDFQCKETGRCLKRHLVCNGDQDCLDGSDEDDCEDVRAIDEDCSQYEPIPGSQKAALG 125 Query: 282 VDCITGEDEVGCAGFASVTQEETEILTADMDAERRRIKSL 321 + +T ED AS + E + E R + Sbjct: 126 YNILTQEDAQSVY-DASYYGGQCETVYNGEWRELRYDSTC 164 >1P3E-A nrPDB Length = 215 Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 37/119 (31%), Gaps = 9/119 (7%) Query: 355 VAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDR 414 +A G +C G I ILT HC+ + + Y +V ++ + Sbjct: 22 IAYITFGGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANMTE 81 Query: 415 IIFHENY-NAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGW 472 Y N G Q D A+I+ + + T +SG+ Sbjct: 82 FYVPSGYINTGASQYDFAVIKTDTNIGNTVGYRSIRQVTNL--------TGTTIKISGY 132 >4A5W-B nrPDB Length = 913 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 18/44 (40%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Query: 213 VCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCC 256 +C ++AD + F+C +G+ I++ C+G NDCGD SDE C Sbjct: 111 LCKIEEADC--KNKFRCDSGRCIARKLECNGENDCGDNSDERDC 152 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 4/44 (9%) Query: 250 QSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293 + +E CK F C SG CI + +CNGE DC DE C Sbjct: 113 KIEEADCK----NKFRCDSGRCIARKLECNGENDCGDNSDERDC 152 Score = 35.0 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 14/70 (20%) Query: 42 SCDKVFCQPWQRCIEGT--CVCKLPYQCPKNGTAV------CATNRRSF------PTYCQ 87 SC C W++C T CVC LP QC K G + +T+ ++ C Sbjct: 840 SCGYDTCYDWEKCSASTSKCVCLLPPQCFKGGNQLYCVKMGSSTSEKTLNICEVGTIRCA 899 Query: 88 QKSLECLHPG 97 + +E LHPG Sbjct: 900 NRKMEILHPG 909 >3OJY-B nrPDB Length = 537 Score = 42.0 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 223 MDDFFQCVNGKYISQMKACDGINDCGDQSDELCCK 257 + F G+ +++ C+G NDCGDQSDE C+ Sbjct: 68 CEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCR 102 Score = 35.0 bits (79), Expect = 0.092, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 3/52 (5%) Query: 243 GINDCGDQSDELCCKACQGKGFHC-KSGVCIPSQYQCNGEVDCITGEDEVGC 293 + DC ++ C + +GF C ++G C+ + CNG+ DC DE C Sbjct: 52 EVEDCV--TNRPCRSQVRCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANC 101 >6H03-D nrPDB Length = 821 Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 5/64 (7%) Query: 48 CQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRS---FP-TYCQQKSLECLHPGTKFLNN 103 CQ W++ CVCK+PY+C + VCA + RS P T C+ L C Sbjct: 680 CQRWEKLQNSRCVCKMPYECGPS-LDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGR 738 Query: 104 GTCT 107 +CT Sbjct: 739 DSCT 742 Score = 36.2 bits (82), Expect = 0.039, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 223 MDDFFQCVNGKYISQMKACDGINDC-GDQSDELCCK 257 + F+C +G+ IS+ C+G +DC D +DE C+ Sbjct: 63 CGERFRCFSGQCISKSLVCNGDSDCDEDSADEDRCE 98 Score = 29.6 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 15/34 (44%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 261 GKGFHCKSGVCIPSQYQCNGEVDC-ITGEDEVGC 293 G+ F C SG CI CNG+ DC DE C Sbjct: 64 GERFRCFSGQCISKSLVCNGDSDCDEDSADEDRC 97 >5IEE-B nrPDB Length = 88 Score = 37.3 bits (85), Expect = 0.020, Method: Composition-based stats. Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 5/69 (7%) Query: 227 FQCVNGKY-ISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIP----SQYQCNGE 281 F C++G I + D DC D SDE AC FHC + P S +G Sbjct: 8 FTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGV 67 Query: 282 VDCITGEDE 290 DC G DE Sbjct: 68 CDCCDGTDE 76 >2WCY-A nrPDB Length = 155 Score = 35.4 bits (80), Expect = 0.073, Method: Composition-based stats. Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 5/64 (7%) Query: 48 CQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRS---FP-TYCQQKSLECLHPGTKFLNN 103 CQ W++ CVCK+PY+C + VCA + RS P T C+ L C Sbjct: 14 CQRWEKLQNSRCVCKMPYECGPS-LDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGR 72 Query: 104 GTCT 107 +CT Sbjct: 73 DSCT 76 >2OUA-A nrPDB Length = 188 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 36/125 (28%), Gaps = 32/125 (25%) Query: 447 PRSIPACVPWSPYLFQPNDTCIVSGW--GREKDNERVFSLQWGEVKLISNCSKFYGNRFY 504 S + P + + T +GW G + + S G V + Sbjct: 87 TVSGSSTAPIGSQVCRSGST---TGWYCGTIQARNQTVSYPQGTVHSL------------ 131 Query: 505 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVAN 564 + CA GDSGG + + T GV S G + Y +V Sbjct: 132 TRTSVCAEP---------GDSGGSFI-----SGTQAQGVTSGGSGNCRTGGTTFYQEVNP 177 Query: 565 -YFDW 568 W Sbjct: 178 MLNSW 182 >4JCN-A nrPDB Length = 216 Score = 33.9 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 38/114 (33%), Gaps = 9/114 (7%) Query: 359 DASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFH 418 D ++ G+ +G ILT H + +K + I D II + Sbjct: 30 DGGYMSGSGVVVGENEILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFVG-QEIIPY 88 Query: 419 ENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGW 472 +D+A++ + PA + S + N+ V+G+ Sbjct: 89 PG------NSDLAILRVS-PNEHNQHIGQVVKPATI-SSNTDTRINENITVTGY 134 >5ILB-A nrPDB Length = 474 Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 30/90 (33%), Gaps = 20/90 (22%) Query: 344 KRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPD 403 A LPWQ + T IG +LT AHC+ + + Sbjct: 17 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVK------------ 62 Query: 404 LKRIVIEYVDRIIFHENYNAGTYQNDIALI 433 + +YV +++ DIAL+ Sbjct: 63 RRGDDRKYVAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 30/90 (33%), Gaps = 20/90 (22%) Query: 344 KRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPD 403 A LPWQ + T IG +LT AHC+ + + Sbjct: 57 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVK------------ 102 Query: 404 LKRIVIEYVDRIIFHENYNAGTYQNDIALI 433 + +YV +++ DIAL+ Sbjct: 103 RRGDDRKYVAKVLV------RGVDCDIALL 126 >1XFE-A nrPDB Length = 83 Score = 31.6 bits (70), Expect = 0.91, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 27/69 (39%), Gaps = 1/69 (1%) Query: 221 SPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNG 280 + F+C +G+ I+ K C+ DC D SDE K C +G C Sbjct: 6 CEGPNKFKCHSGECITLDKVCNMARDCRDWSDEP-IKECGTNECLDNNGGCSHVCNDLKI 64 Query: 281 EVDCITGED 289 +C+ + Sbjct: 65 GYECLCPDG 73 >1NUB-A nrPDB Length = 229 Score = 30.4 bits (67), Expect = 2.4, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 3/44 (6%) Query: 59 CVCKLPYQCPK---NGTAVCATNRRSFPTYCQQKSLECLHPGTK 99 CVC+ P CP VC+ + ++F + C + +C GTK Sbjct: 27 CVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTK 70 >3SC7-X nrPDB Length = 516 Score = 29.6 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 23/63 (36%), Gaps = 2/63 (3%) Query: 131 LVDQDKTMFICKS--SWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRG 188 L +D +F + +W M A+ L F ADT SDL S L G Sbjct: 172 LESRDPKVFFHRQSGNWIMVLAHGGQDKLSFWTSADTINWTWQSDLKSTSINGLSSDITG 231 Query: 189 LET 191 E Sbjct: 232 WEV 234 >3CMG-A nrPDB Length = 667 Score = 28.9 bits (63), Expect = 6.0, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%) Query: 91 LECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSS 144 L+ PG + E K + N ++G E++++ D T ICK S Sbjct: 156 LDYASPGVYLVQEVVSPQEAKVCAKVNLSNRAADGTAELQVLVTDGTKVICKES 209 >1P7O-A nrPDB Length = 124 Score = 28.9 bits (63), Expect = 6.5, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 36/94 (38%), Gaps = 13/94 (13%) Query: 192 SLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQS 251 ++ +CT R + C + +P+D+ +C C ++C D++ Sbjct: 7 NMIKCTIPGREPLLAFSNYGCYCGKGGSGTPVDELDRC-----------CQTHDNCYDKA 55 Query: 252 DE--LCCKACQGKGFHCKSGVCIPSQYQCNGEVD 283 ++ C G F+ S C + CN + D Sbjct: 56 EKLPECKGILSGPYFNTYSYDCTDGKLTCNDQND 89 >1DT2-A nrPDB Length = 245 Score = 28.9 bits (63), Expect = 6.5, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 48/145 (33%), Gaps = 11/145 (7%) Query: 357 IKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRII 416 + G+ IG I+T H R + + I T + Y Sbjct: 41 VFVKGSTLATGVLIGKNTIVTNYHVAREAAKNPSNIIFTPAQNRDAEKNEFPTPYGKFEA 100 Query: 417 FHENYNAGTYQNDIALIEMKKDGN---KKDCELPRSIPACVPWSPYLFQPNDTCIVSGWG 473 + D+A+I++K + D P +IP + Q D + G+ Sbjct: 101 EEIKESPYGQGLDLAIIKLKPNEKGESAGDLIQPANIPDHI-----DIQKGDKYSLLGY- 154 Query: 474 REKDNERVFSLQWGEVKLISNCSKF 498 N +SL ++++ ++ F Sbjct: 155 --PYNYSAYSLYQSQIEMFNDSQYF 177 >2EA3-A nrPDB Length = 189 Score = 28.9 bits (63), Expect = 6.5, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 40/146 (27%), Gaps = 40/146 (27%) Query: 427 QNDIALIE-------MKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNE 479 ND A + + + N + + P + + T +GW Sbjct: 54 GNDYAFVRTGAGVNLLAQVNNYSGGRVQVAGHTAAPVGSAVCRSGST---TGW------- 103 Query: 480 RVFSLQWGEVKLISNCSKFYGNRFYE---KEMECAGTYDGSIDACKGDSGGPLVCMDANN 536 G + + N S Y + CA GDSGG L+ + Sbjct: 104 -----HCGTITAL-NSSVTYPEGTVRGLIRTTVCAEP---------GDSGGSLLAGNQ-- 146 Query: 537 VTYVWGVVSWGENCGKPEFPGVYTKV 562 GV S G + + V Sbjct: 147 ---AQGVTSGGSGNCRTGGTTFFQPV 169 >5WJF-A nrPDB Length = 143 Score = 28.5 bits (62), Expect = 7.6, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 25/70 (35%), Gaps = 4/70 (5%) Query: 201 RRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQ 260 R GY F T A+ + F C+ + C+ G + + CK C Sbjct: 44 RVCAGYFRFKKFCSSTHNAECECIEGFHCLGPQCT----RCEKDCRPGQELTKQGCKTCS 99 Query: 261 GKGFHCKSGV 270 F+ ++G Sbjct: 100 LGTFNDQNGT 109 >5WZN-A nrPDB Length = 640 Score = 28.5 bits (62), Expect = 9.6, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 28/108 (25%), Gaps = 6/108 (5%) Query: 238 MKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFA 297 + C+ ++C + + C + C + + EV V C Sbjct: 436 VFTCNEGDECSHPEHRMTRRECYERRAECFEYLLAHGILTSSEEVSDWAVPSLVFCHY-- 493 Query: 298 SVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKR 345 + DA R I L L R+ GG Sbjct: 494 ----APYDFQMRSPDAPRHGIPVPLYNLVYHDCVIQPWMMDRVAGGDD 537 >2PFE-A nrPDB Length = 186 Score = 28.1 bits (61), Expect = 9.7, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 15/51 (29%), Gaps = 14/51 (27%) Query: 504 YEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPE 554 + CA GDSGGP + GV S G + Sbjct: 128 LTRTTACAEG---------GDSGGP-----WLTGSQAQGVTSGGTGDCRSG 164 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.134 0.445 Lambda K H 0.267 0.0413 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,756,854 Number of Sequences: 36641 Number of extensions: 1068854 Number of successful extensions: 3892 Number of sequences better than 10.0: 207 Number of HSP's better than 10.0 without gapping: 339 Number of HSP's successfully gapped in prelim test: 43 Number of HSP's that attempted gapping in prelim test: 2111 Number of HSP's gapped (non-prelim): 496 length of query: 583 length of database: 10,336,785 effective HSP length: 102 effective length of query: 481 effective length of database: 6,599,403 effective search space: 3174312843 effective search space used: 3174312843 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 62 (28.5 bits)