BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05122 (381 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1QH4-A nrPDB 788 0.0 4Q2R-A nrPDB 729 0.0 1U6R-A nrPDB 660 0.0 1VRP-A nrPDB 657 0.0 1CRK-A nrPDB 514 e-146 1QK1-A nrPDB 503 e-143 4Z9M-A nrPDB 502 e-142 3JU6-A nrPDB 466 e-131 3L2D-A nrPDB 414 e-116 3JPZ-A nrPDB 413 e-116 4RF9-A nrPDB 296 9e-81 4BG4-B nrPDB 288 3e-78 2J1Q-A nrPDB 285 3e-77 5ZHQ-A nrPDB 280 7e-76 4GVZ-A nrPDB 276 7e-75 5U8E-A nrPDB 272 2e-73 4WO8-A nrPDB 237 6e-63 6FH2-A nrPDB 91 9e-19 5O9X-A nrPDB 34 0.12 6D1P-A nrPDB 28 4.9 >1QH4-A nrPDB Length = 380 Score = 788 bits (2035), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/380 (100%), Positives = 380/380 (100%) Query: 2 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV 61 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV Sbjct: 1 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV 60 Query: 62 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL 121 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL Sbjct: 61 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL 120 Query: 122 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD 181 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD Sbjct: 121 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD 180 Query: 182 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ 241 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ Sbjct: 181 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ 240 Query: 242 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN 301 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN Sbjct: 241 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN 300 Query: 302 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI 361 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI Sbjct: 301 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI 360 Query: 362 EMEKRLEKGQSIDDLMPAQK 381 EMEKRLEKGQSIDDLMPAQK Sbjct: 361 EMEKRLEKGQSIDDLMPAQK 380 >4Q2R-A nrPDB Length = 381 Score = 729 bits (1882), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/381 (90%), Positives = 366/381 (96%) Query: 1 MPFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTG 60 MPFSNSHN LK+++ +DE+PDLS HNNHMAKVLT +LY +LR + T SGFT+DDVIQTG Sbjct: 1 MPFSNSHNTLKLRFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTG 60 Query: 61 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDD 120 VDNPGHP+IMTVGCVAGDEESY+VFKELFDP+IEDRHGGYKPTDEHKTDLN DNLQGGDD Sbjct: 61 VDNPGHPYIMTVGCVAGDEESYDVFKELFDPIIEDRHGGYKPTDEHKTDLNPDNLQGGDD 120 Query: 121 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMT 180 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKL+VEAL SL GDL G+YYAL++MT Sbjct: 121 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMT 180 Query: 181 DAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM 240 +AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM Sbjct: 181 EAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM 240 Query: 241 QKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP 300 QKGGNMKEVFTRFC GLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP Sbjct: 241 QKGGNMKEVFTRFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP 300 Query: 301 NLGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL 360 +LGKHEKF EVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL Sbjct: 301 HLGKHEKFPEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL 360 Query: 361 IEMEKRLEKGQSIDDLMPAQK 381 IEME+RLE+GQ+IDDLMPAQK Sbjct: 361 IEMEQRLEQGQAIDDLMPAQK 381 >1U6R-A nrPDB Length = 380 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/380 (80%), Positives = 345/380 (90%) Query: 2 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV 61 PF N+HN K+ Y ++EYPDLS HNNHMAKVLT DLYKKLRD++T SGFTLDDVIQTGV Sbjct: 1 PFGNTHNKYKLNYKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGV 60 Query: 62 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL 121 DNPGHPFIMTVGCVAGDEESY VFK+LFDP+I+DRHGG+KPTD+HKTDLN +NL+GGDDL Sbjct: 61 DNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDDL 120 Query: 122 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD 181 DP+YVLSSRVRTG+SI+G+ LPPHCSRGERRA+EKLSVEAL SL G+ KGKYY L++MT+ Sbjct: 121 DPHYVLSSRVRTGKSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTE 180 Query: 182 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ 241 EQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNK+FLVW+NEEDHLRVISM+ Sbjct: 181 QEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISME 240 Query: 242 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN 301 KGGNMKEVF RFC GL +IE +FK + FMWN HLGY+LTCPSNLGTGLR GVH+KL + Sbjct: 241 KGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAH 300 Query: 302 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI 361 L KH KF E+L RLRLQKRGTGGVDTAAVG VFD+SNADRLG SEVE VQ+VVDGVKL++ Sbjct: 301 LSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDISNADRLGSSEVEQVQLVVDGVKLMV 360 Query: 362 EMEKRLEKGQSIDDLMPAQK 381 EMEK+LEKGQSIDD++PAQK Sbjct: 361 EMEKKLEKGQSIDDMIPAQK 380 >1VRP-A nrPDB Length = 381 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/381 (79%), Positives = 341/381 (89%) Query: 1 MPFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTG 60 MPF N+HN K+ YS +E+PDLS HNNHMAK LTLD+YKKLRD++T SGFTLDD+IQTG Sbjct: 1 MPFGNTHNKWKLNYSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDIIQTG 60 Query: 61 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDD 120 VDNPGHPFIMTVGCVAGDEE YEVFK+LFDPVIEDRHGGYKPTD+HKTDLN +NL+GGDD Sbjct: 61 VDNPGHPFIMTVGCVAGDEECYEVFKDLFDPVIEDRHGGYKPTDKHKTDLNQENLKGGDD 120 Query: 121 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMT 180 LDPNYVLSSRVRTGRSI+G LPPHCSRGERR +EKL ++ L +L G+ +GKYY L +M+ Sbjct: 121 LDPNYVLSSRVRTGRSIKGIALPPHCSRGERRLVEKLCIDGLATLTGEFQGKYYPLSSMS 180 Query: 181 DAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM 240 DAEQQQLIDDHFLFDKP+SPLLLASGMARDWPD RGIWHN++KTFLVW+NEEDHLRVISM Sbjct: 181 DAEQQQLIDDHFLFDKPISPLLLASGMARDWPDGRGIWHNNDKTFLVWVNEEDHLRVISM 240 Query: 241 QKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP 300 QKGGNMKEVF RFC GL +IE +F FMWN HLGY+LTCPSNLGTGLR GVH+K+P Sbjct: 241 QKGGNMKEVFRRFCVGLKKIEDIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIP 300 Query: 301 NLGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL 360 +L KHEKF EVLKR RLQKRGTGGVDTAAVG ++D+SNADRLGFSEVE VQMVVDGVKL+ Sbjct: 301 HLCKHEKFSEVLKRTRLQKRGTGGVDTAAVGSIYDISNADRLGFSEVEQVQMVVDGVKLM 360 Query: 361 IEMEKRLEKGQSIDDLMPAQK 381 +EMEKRLE G+SIDDLMPAQK Sbjct: 361 VEMEKRLENGKSIDDLMPAQK 381 >1CRK-A nrPDB Length = 380 Score = 514 bits (1325), Expect = e-146, Method: Compositional matrix adjust. Identities = 246/356 (69%), Positives = 286/356 (80%), Gaps = 2/356 (0%) Query: 19 EYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGD 78 +YPDL HNN MA+ LT +Y KLRD+ T +G++LD IQTGVDNPGHPFI TVG VAGD Sbjct: 14 DYPDLRKHNNCMAECLTPAIYAKLRDKLTPNGYSLDQCIQTGVDNPGHPFIKTVGMVAGD 73 Query: 79 EESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVRTGRSI 137 EESYEVF E+FDPVI+ RH GY P T +H TDL+A + G D YVLSSRVRTGRSI Sbjct: 74 EESYEVFAEIFDPVIKARHNGYDPRTMKHHTDLDASKITHGQ-FDERYVLSSRVRTGRSI 132 Query: 138 RGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKP 197 RG LPP CSR ERR +E + V AL L GDL GKYY+L NM++ +QQQLIDDHFLFDKP Sbjct: 133 RGLSLPPACSRAERREVENVVVTALAGLKGDLSGKYYSLTNMSERDQQQLIDDHFLFDKP 192 Query: 198 VSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGL 257 VSPLL +GMARDWPDARGIWHN++KTFLVWINEEDH RVISM+KGGNMK VF RFC GL Sbjct: 193 VSPLLTCAGMARDWPDARGIWHNNDKTFLVWINEEDHTRVISMEKGGNMKRVFERFCRGL 252 Query: 258 TQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRL 317 ++E L K + +EFMWN LGY+LTCPSNLGTGLRAGVH+KLP L K +F ++L+ LRL Sbjct: 253 KEVERLIKERGWEFMWNERLGYVLTCPSNLGTGLRAGVHVKLPRLSKDPRFPKILENLRL 312 Query: 318 QKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQSI 373 QKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ EK+LEKGQ I Sbjct: 313 QKRGTGGVDTAAVADVYDISNLDRMGRSEVELVQIVIDGVNYLVDCEKKLEKGQDI 368 >1QK1-A nrPDB Length = 379 Score = 503 bits (1296), Expect = e-143, Method: Compositional matrix adjust. Identities = 248/361 (68%), Positives = 289/361 (80%), Gaps = 2/361 (0%) Query: 14 YSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVG 73 Y EYPDL HNN MA LT +Y +L D+ T +G+TLD IQTGVDNPGHPFI TVG Sbjct: 9 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 68 Query: 74 CVAGDEESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVR 132 VAGDEE+YEVF +LFDPVI++RH GY P T +H TDL+A ++ G D YVLSSRVR Sbjct: 69 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 127 Query: 133 TGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHF 192 TGRSIRG LPP C+R ERR +E++ V+AL L GDL G+YY L MT+AEQQQLIDDHF Sbjct: 128 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 187 Query: 193 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 252 LFDKPVSPLL A+GMARDWPDARGIWHN+ K+FL+W+NEEDH RVISM+KGGNMK VF R Sbjct: 188 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 247 Query: 253 FCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVL 312 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVHIKLP L K +F ++L Sbjct: 248 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 307 Query: 313 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQS 372 + LRLQKRGTGGVDTAA GGVFD+SN DRLG SEVELVQ+V+DGV LI+ E+RLE+GQ Sbjct: 308 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 367 Query: 373 I 373 I Sbjct: 368 I 368 >4Z9M-A nrPDB Length = 392 Score = 502 bits (1292), Expect = e-142, Method: Compositional matrix adjust. Identities = 237/356 (66%), Positives = 284/356 (79%), Gaps = 2/356 (0%) Query: 19 EYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGD 78 +YPDL HNN MA+ LT +Y KLR++ T +G+TLD IQTGVDNPGHPFI TVG VAGD Sbjct: 29 DYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGD 88 Query: 79 EESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVRTGRSI 137 EESYEVF +LFDPVI+ RH GY P +H TDL+A + G D +YVLSSRVRTGRSI Sbjct: 89 EESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVRTGRSI 147 Query: 138 RGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKP 197 RG LPP C+R ERR +E +++ AL L GDL G+YY L MT+ +QQ+LIDDHFLFDKP Sbjct: 148 RGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKP 207 Query: 198 VSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGL 257 VSPLL +GMARDWPDARGIWHN +KTFL+WINEEDH RVISM+KGGNMK VF RFC GL Sbjct: 208 VSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGL 267 Query: 258 TQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRL 317 ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVH+++P L K +F ++L+ LRL Sbjct: 268 KEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRL 327 Query: 318 QKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQSI 373 QKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ EK+LE+GQ I Sbjct: 328 QKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDI 383 >3JU6-A nrPDB Length = 370 Score = 466 bits (1198), Expect = e-131, Method: Compositional matrix adjust. Identities = 230/372 (61%), Positives = 276/372 (74%), Gaps = 6/372 (1%) Query: 8 NLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHP 67 NL + KY D++P+ H + ++K LT D+Y KLRD T SG+TLD IQ GVDNP Sbjct: 3 NLNQKKYPAKDDFPNFEGHKSLLSKYLTADMYAKLRDVATPSGYTLDRAIQNGVDNPD-- 60 Query: 68 FIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDLDPNYVL 127 +G +AGDEE+Y VF +LFDPVIE+ H G+K TD HKTDL+A + D LDP YV+ Sbjct: 61 --FHLGLLAGDEETYTVFADLFDPVIEEYHNGFKKTDNHKTDLDASKILD-DVLDPAYVI 117 Query: 128 SSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQL 187 SSRVRTGR+IRG L PH R ERRAIEK+ EAL SL DLKGKYY+L M + QQQL Sbjct: 118 SSRVRTGRNIRGMALSPHVCRSERRAIEKMVSEALNSLAADLKGKYYSLMKMDEKTQQQL 177 Query: 188 IDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMK 247 IDDHFLFD+PVS + GMARD+PD RGIWHND K FLVWINEEDH R+ISMQ GGNMK Sbjct: 178 IDDHFLFDRPVSRHFTSGGMARDFPDGRGIWHNDKKNFLVWINEEDHTRIISMQMGGNMK 237 Query: 248 EVFTRFCTGLTQIETLFKSKN-YEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHE 306 EVF RF GLT++E K K EFM N HLG++LTCPSNLGTG+R VH KLP++ K + Sbjct: 238 EVFERFTRGLTEVEKHIKDKTGKEFMKNDHLGFVLTCPSNLGTGVRCSVHAKLPHMAKDK 297 Query: 307 KFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKR 366 +F E+ ++RLQKRGT G T +VGGV+D+SN DRLG SEVE V V+ GVK+LIEMEK+ Sbjct: 298 RFEEICTKMRLQKRGTSGEFTESVGGVYDISNLDRLGSSEVEQVNCVIKGVKVLIEMEKK 357 Query: 367 LEKGQSIDDLMP 378 LEKG+SIDDL+P Sbjct: 358 LEKGESIDDLVP 369 >3L2D-A nrPDB Length = 390 Score = 414 bits (1065), Expect = e-116, Method: Compositional matrix adjust. Identities = 208/368 (56%), Positives = 259/368 (70%), Gaps = 4/368 (1%) Query: 13 KYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFI-MT 71 K+ D +PDLS HNN MA LT +LY+K D+ T +G T D IQTGVDNPG+ F Sbjct: 24 KFKAADNFPDLSKHNNVMASQLTKELYEKYWDKVTPNGVTFDKCIQTGVDNPGNKFYGKK 83 Query: 72 VGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKT-DLNADNLQGGDDLDPNYVLSSR 130 GCV GDE SYE +KE FD IE+ H +KP+D+H DL+ + L GG + YV S R Sbjct: 84 TGCVFGDEYSYECYKEFFDKCIEEIHH-FKPSDKHPAPDLDHNKLVGGV-FEDKYVKSCR 141 Query: 131 VRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDD 190 +R GRS++G CLPP SR ERR +EK+ +ALG L GDL GKYY L M + +Q+QLI+D Sbjct: 142 IRCGRSVKGVCLPPAMSRAERRLVEKVVSDALGGLKGDLAGKYYPLTTMNEKDQEQLIED 201 Query: 191 HFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVF 250 HFLF+KP LL SG ARDWPD RGIWHN+ K FLVWINEEDH+RVISMQKGG++K VF Sbjct: 202 HFLFEKPTGALLTTSGCARDWPDGRGIWHNNEKNFLVWINEEDHIRVISMQKGGDLKAVF 261 Query: 251 TRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGE 310 +RF GL ++E L K + M N LGYI TCP+N+GT +RA VH++L L KH +F E Sbjct: 262 SRFARGLLEVERLMKECGHGLMHNDRLGYICTCPTNMGTVVRASVHLRLAFLEKHPRFDE 321 Query: 311 VLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKG 370 +L +LRL KRGTGG + A +D+SN RLG SE ELVQ++VDGV LLI +K+LE G Sbjct: 322 MLGKLRLGKRGTGGESSLATDSTYDISNWARLGKSERELVQVLVDGVNLLIACDKKLEAG 381 Query: 371 QSIDDLMP 378 QSIDD++P Sbjct: 382 QSIDDMIP 389 >3JPZ-A nrPDB Length = 366 Score = 413 bits (1061), Expect = e-116, Method: Compositional matrix adjust. Identities = 202/361 (55%), Positives = 251/361 (69%), Gaps = 6/361 (1%) Query: 20 YPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDE 79 +PD + H + + L ++Y++L ++T+ G T+D VIQ VDN G+ +G +AGDE Sbjct: 11 FPDYANHGCVVGRHLNFEMYQRLFGKKTAHGVTVDKVIQPSVDNFGN----CIGLIAGDE 66 Query: 80 ESYEVFKELFDPVIEDRHGGYKPTDEHKT-DLNADNLQGGDDLDPNYVLSSRVRTGRSIR 138 ESYEVFKELFD VI ++H G+ P D DL+A L GG D YV S R+RTGR IR Sbjct: 67 ESYEVFKELFDAVINEKHKGFGPNDSQPAPDLDASKLVGGQ-FDEKYVKSCRIRTGRGIR 125 Query: 139 GFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPV 198 G C PP C+RGERR +E++ AL L GDL G YY L MT ++ QLI DHFLF KP Sbjct: 126 GLCYPPSCTRGERREVERVITTALAGLSGDLSGTYYPLSKMTPEQENQLIADHFLFQKPT 185 Query: 199 SPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLT 258 L++ S RDWPDARGIWHN+ KTFL+WINEEDH+RVISMQKGGN+K VF RF GL Sbjct: 186 GHLMVNSASVRDWPDARGIWHNNEKTFLIWINEEDHMRVISMQKGGNVKAVFERFGRGLN 245 Query: 259 QIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRLQ 318 I K E+MWN LGY+ CPSNLGTGLRA VH++L L KH KF +++ L+LQ Sbjct: 246 AIAEQMKKNGREYMWNQRLGYLCACPSNLGTGLRASVHVQLHQLSKHPKFEDIVVALQLQ 305 Query: 319 KRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQSIDDLMP 378 KRGTGG TAAV V+D+SNA RL SE E VQ+++DGVK LI+ME+ LE G+SIDDL+P Sbjct: 306 KRGTGGEHTAAVDDVYDISNAARLKKSEREFVQLLIDGVKKLIDMEQALEAGKSIDDLIP 365 Query: 379 A 379 A Sbjct: 366 A 366 >4RF9-A nrPDB Length = 718 Score = 296 bits (758), Expect = 9e-81, Method: Compositional matrix adjust. Identities = 157/350 (44%), Positives = 222/350 (63%), Gaps = 17/350 (4%) Query: 30 MAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELF 89 + K LT +++ L++++T G TL D I +GV N VG AGDEESY +F LF Sbjct: 34 VKKYLTPKVFESLKNKKTKLGITLWDCINSGVVN----LDSGVGVYAGDEESYTLFGPLF 89 Query: 90 DPVIEDRHGGYKPTDEHKTDLNADNLQGGDDLDP--NYVLSSRVRTGRSIRGFCLPPHCS 147 D +IED H YK H +D+N +++ DLDP Y+ S+R+R RS++G+ L P + Sbjct: 90 DAIIEDYHSPYKLATGHNSDMNPAHVKA-PDLDPANRYIRSTRIRVARSLKGYGLAPGVT 148 Query: 148 RGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGM 207 + R IEK V L SL GDL GKYY L M + +QQL+DDHFLF K L A+G+ Sbjct: 149 KAHRLEIEKKVVGVLTSLTGDLAGKYYPLSGMDEKTRQQLVDDHFLFKKG-DRFLEAAGI 207 Query: 208 ARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSK 267 ++WP+ RGI+HN++KTFLVW+NEEDHLR+ISM+KG ++ VF+R C + +I+ K Sbjct: 208 NKEWPEGRGIYHNNDKTFLVWLNEEDHLRIISMEKGSDIGSVFSRLCRAVNEID-----K 262 Query: 268 NYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRLQKRGTGGVDT 327 F GY+ +CPSNLGTG+RA VH+K+P+ +H F +L + +Q RG G + Sbjct: 263 KLGFQHTKKHGYLTSCPSNLGTGMRASVHVKIPHAKEHPDFENILTKYHIQARGIHGEHS 322 Query: 328 AAVG---GVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKR-LEKGQSI 373 + G GV+D+SN RLG SEV+ VQ + DGVK L+E+EK + K +S+ Sbjct: 323 ESTGEDAGVYDISNRRRLGLSEVQCVQDMYDGVKALMELEKEAIAKKRSV 372 Score = 288 bits (736), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 149/341 (43%), Positives = 213/341 (62%), Gaps = 16/341 (4%) Query: 30 MAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELF 89 + K LT +L+ L+D++T+ G +L D I +GV+N + G AGDEE Y +F LF Sbjct: 386 LRKYLTPELFDSLKDKKTAKGISLYDCINSGVEN----LDSSCGVYAGDEECYTLFAPLF 441 Query: 90 DPVIEDRHGGYKPTDEHKTDLNADNLQGGDDLDP--NYVLSSRVRTGRSIRGFCLPPHCS 147 D ++ED H YK ++H +D+N + + +LDP Y+ S+R+R R+++G+ L P + Sbjct: 442 DKIVEDYHSPYKLANKHTSDMNPEKVDA-PNLDPEGTYIRSTRIRVARNVKGYALTPGLT 500 Query: 148 RGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGM 207 R ER IE+ V L SL GDL G+YY L M +A +Q+L++DHFLF K L A+G+ Sbjct: 501 RNERLDIERKVVGVLSSLTGDLAGQYYPLTGMDEATRQKLVNDHFLFKKG-DRFLEAAGV 559 Query: 208 ARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSK 267 + WP+ RGI+HN++KTFLVWINEED LR+ISM+KG ++ VF R C + +I+ K Sbjct: 560 NKLWPEGRGIFHNNDKTFLVWINEEDQLRIISMEKGSDIGSVFGRLCRAVNEID-----K 614 Query: 268 NYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRLQKRGTGG--- 324 F GY+ CP+NLGTG+RA VH+K+P H F ++ +Q RG G Sbjct: 615 QLGFQHTDAHGYLSGCPTNLGTGMRASVHVKIPKASAHPDFQKICDEFHIQARGIHGEHS 674 Query: 325 VDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEK 365 V T GVFD+SN RLG SEV+ VQ + +GVK L+E+EK Sbjct: 675 VSTGEDAGVFDISNRRRLGLSEVQCVQDMYNGVKKLLEIEK 715 >4BG4-B nrPDB Length = 356 Score = 288 bits (736), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 157/340 (46%), Positives = 213/340 (62%), Gaps = 12/340 (3%) Query: 30 MAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELF 89 + K LT D++ KL+D++TS G TL DVIQ+GV+N VG A D E+Y +F LF Sbjct: 27 LKKYLTKDVFDKLKDKKTSLGATLLDVIQSGVEN----LDSGVGIYAPDAEAYTLFAPLF 82 Query: 90 DPVIEDRHGGYKPTDEH-KTDLNADNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSR 148 DP+IED H G+K TD+H D N D + +V+S+RVR GRS++G+ P + Sbjct: 83 DPIIEDYHVGFKQTDKHPNKDFGDVNSFVNVDPEGKFVISTRVRCGRSMQGYPFNPCLTE 142 Query: 149 GERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGMA 208 + + +E L SL G+LKG YY L M+ QQ+LIDDHFLF K L A+ Sbjct: 143 SQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKEVQQKLIDDHFLF-KEGDRFLQAANAC 201 Query: 209 RDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKN 268 R WP RGI+HNDNKTFLVW+NEEDHLR+ISMQ GG++ +VF R + + +IE K Sbjct: 202 RYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVFRRLTSAVNEIE-----KR 256 Query: 269 YEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKH-EKFGEVLKRLRLQKRGTGGVDT 327 F + LG++ CP+NLGT +RA VHIKLP L + EK EV + LQ RGT G T Sbjct: 257 IPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYNLQVRGTRGEHT 316 Query: 328 AAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRL 367 A GG++D+SN R+G +E + V+ + DG+ LI++EK + Sbjct: 317 EAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEM 356 >2J1Q-A nrPDB Length = 357 Score = 285 bits (728), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 158/339 (46%), Positives = 210/339 (61%), Gaps = 14/339 (4%) Query: 30 MAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELF 89 + K LT +++ +L+ +QT G TL DVIQ+GV+N +G A D ESY +F L Sbjct: 27 LKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVEN----LDSGIGVYAPDAESYTLFAALL 82 Query: 90 DPVIEDRHGGYKPTDEHKTDLNADNLQGGDDLDPN--YVLSSRVRTGRSIRGFCLPPHCS 147 DP+IED H G+KP+D+ + D L D+DP+ YV+S+RVR GRS+ G+ P Sbjct: 83 DPIIEDYHKGFKPSDKQPPKDSGD-LNTFIDVDPDKKYVISTRVRCGRSLEGYPFNPCLK 141 Query: 148 RGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGM 207 + + +E L S+ G+L+GKYY L MT Q+QLIDDHFLF K L A+ Sbjct: 142 KQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLIDDHFLF-KEGDRFLQAAHA 200 Query: 208 ARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSK 267 + WP RGI+HND KTFLVW+NEEDHLR+ISMQKGGN+KEVF R T + IE K Sbjct: 201 CKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKEVFGRLVTAVGVIEEKVK-- 258 Query: 268 NYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGK-HEKFGEVLKRLRLQKRGTGGVD 326 F + LG++ CP+NLGT +RA VHIKLP LG +K EV + LQ RGT G Sbjct: 259 ---FSRDDRLGFLTFCPTNLGTTIRASVHIKLPKLGADRKKLEEVAAKYNLQVRGTAGEH 315 Query: 327 TAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEK 365 + + GV+D+SN RLG SE E V+ + DG+ LI+ E+ Sbjct: 316 SDSPDGVYDISNKRRLGLSEYEAVKEMQDGILELIKAEE 354 >5ZHQ-A nrPDB Length = 357 Score = 280 bits (716), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 154/341 (45%), Positives = 210/341 (61%), Gaps = 12/341 (3%) Query: 30 MAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELF 89 + K LT ++ +L+ ++TS G TL DVIQ+GV+N VG A D E+Y +F LF Sbjct: 27 LKKYLTKSVFDQLKGKKTSLGATLLDVIQSGVEN----LDSGVGVYAPDAEAYTLFAPLF 82 Query: 90 DPVIEDRHGGYKPTDEH-KTDLNADNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSR 148 DP+IED H G+K TD+H D N D D +V+S+RVR GRS+ G+ P + Sbjct: 83 DPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCGRSMEGYPFNPCLTE 142 Query: 149 GERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGMA 208 + + +E L +L G+LKG YY L MT QQ+LIDDHFLF K L A+ Sbjct: 143 AQYKEMESKVSSTLSNLEGELKGTYYPLTGMTKDVQQKLIDDHFLF-KEGDRFLQAANAC 201 Query: 209 RDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKN 268 R WP RGI+HNDNKTFLVW +EEDHLR+ISMQ GG++ +V+ R + + +IE K Sbjct: 202 RYWPTGRGIYHNDNKTFLVWCDEEDHLRIISMQMGGDLGQVYRRLVSAVNEIE-----KR 256 Query: 269 YEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKH-EKFGEVLKRLRLQKRGTGGVDT 327 F + LG++ CP+NLGT +RA VHIKLP L + EK EV + LQ RGT G T Sbjct: 257 VPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYSLQVRGTRGEHT 316 Query: 328 AAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLE 368 A GGV+D+SN R+G +E + V+ + DG+ LI++EK ++ Sbjct: 317 EAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ 357 >4GVZ-A nrPDB Length = 357 Score = 276 bits (707), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 151/338 (44%), Positives = 207/338 (61%), Gaps = 12/338 (3%) Query: 30 MAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELF 89 + K LT D++ +++++T G TL DVIQ+GV+N VG A D ESY F LF Sbjct: 27 LKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVEN----LDSGVGIYAPDAESYRTFGPLF 82 Query: 90 DPVIEDRHGGYKPTDEHKTDLNAD-NLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSR 148 DP+I+D HGG+K TD+H D N G D +++S+RVR GRS++G+ P + Sbjct: 83 DPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPCLTA 142 Query: 149 GERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGMA 208 + + +E+ L S+ +LKG YY L M+ A QQQLIDDHFLF K L + Sbjct: 143 EQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLF-KEGDRFLQTANAC 201 Query: 209 RDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKN 268 R WP RGI+HND KTFLVW+NEEDHLR+ISMQKGG++K V+ R T + IE+ Sbjct: 202 RYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIES-----K 256 Query: 269 YEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGE-VLKRLRLQKRGTGGVDT 327 F + G++ CP+NLGT +RA VHI+LP L K K E + + LQ RGT G T Sbjct: 257 LPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRGEHT 316 Query: 328 AAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEK 365 + GGV+D+SN RLG +E + V+ + DG+ +I+MEK Sbjct: 317 ESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEK 354 >5U8E-A nrPDB Length = 384 Score = 272 bits (696), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 147/338 (43%), Positives = 203/338 (60%), Gaps = 12/338 (3%) Query: 30 MAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELF 89 + K L +++ + + +T+ G TL D IQ+GV+N VG A D E+Y +F +F Sbjct: 54 LKKYLNREVFDQCKSLKTALGATLLDCIQSGVEN----LDSGVGIYAPDAEAYTLFAPIF 109 Query: 90 DPVIEDRHGGYKPTDEHK-TDLNADNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSR 148 +P+IED H G+KPTD+H TD N D YV+S+ VR GRS++G+ P + Sbjct: 110 NPIIEDYHEGFKPTDKHPPTDFGDINTIVNVDPSGKYVVSTHVRCGRSLKGYPFNPCLTE 169 Query: 149 GERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGMA 208 + +E G+ G+LKGKYY L M A QQQLIDDHFLF K L A+ Sbjct: 170 ANYKEMEDKVSAIFGTFEGELKGKYYPLTGMDKATQQQLIDDHFLF-KEGDRFLQAANAC 228 Query: 209 RDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKN 268 R WP RGI+HND KTFLVW+NEEDHLR+ISMQKGG++K +F R + IE+ Sbjct: 229 RYWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGDLKTIFQRLVNAVNTIES-----K 283 Query: 269 YEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVL-KRLRLQKRGTGGVDT 327 F + LG++ CP+NLGT +RA VHI LP L K +K E + + LQ RGT G T Sbjct: 284 LPFSRDDRLGFLTFCPTNLGTTIRASVHIALPKLAKDKKQLEAIAAKFNLQVRGTRGEHT 343 Query: 328 AAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEK 365 + GGV+D+SN R+G +E + V+ + DG+ +I+ME+ Sbjct: 344 ESEGGVYDISNKRRMGLTEYQAVKEMQDGILEMIKMEE 381 >4WO8-A nrPDB Length = 716 Score = 237 bits (605), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 136/349 (38%), Positives = 200/349 (57%), Gaps = 17/349 (4%) Query: 24 SVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYE 83 S+ + K LT ++ KK ++T+ G TL +I+ G N ++ G+ E Y Sbjct: 380 SIEKCYTRKYLTPEIIKKYDGKRTTHGATLAHMIRNGAYNN-----RSICPRTGEAECYS 434 Query: 84 VFKELFDPVIEDRHGGYKPTDEHKTDLNAD--NLQGGDDLDPN--YVLSSRVRTGRSIRG 139 F + DP+I D HG +H D L GD LDP +++S+RVR GRS+ G Sbjct: 435 TFIDYLDPLICDYHGVKDSAFKHPAPTFGDLSKLPFGD-LDPTGKFIVSTRVRVGRSVEG 493 Query: 140 FCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVS 199 F P S+ +R +E++ AL L G+ G YY L +M + +++QL++DHFLF K Sbjct: 494 FLFPTIMSKTDRIKLEQVISGALKGLTGEHAGTYYPLTDMKEEDRKQLVEDHFLF-KNDD 552 Query: 200 PLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQ 259 P+L +G RDWP RGI+HN++KTFLVW+ EEDH+R+ISMQ+GGN+ V+ R G+ Sbjct: 553 PVLRDAGGYRDWPVGRGIFHNNSKTFLVWVCEEDHMRIISMQQGGNLAAVYKRLIEGINA 612 Query: 260 IETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKH-EKFGEVLKRLRLQ 318 I K+ +F + GYI CPSNLGT +RA V +K+P L +K E+ + LQ Sbjct: 613 I-----GKSMKFAHSDKYGYITCCPSNLGTSMRASVLLKIPKLSSQPKKLDEICAKYMLQ 667 Query: 319 KRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRL 367 RG G T + G +D+SN RLG +E++ + +GV +IE+EK L Sbjct: 668 ARGLYGEHTESPDGTYDISNKRRLGLTELQAAHEMAEGVAKMIEIEKGL 716 Score = 234 bits (596), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 137/341 (40%), Positives = 197/341 (57%), Gaps = 14/341 (4%) Query: 32 KVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDP 91 K LT D+ KK + +TS G TL + T NPG ++ C D +YE F++ FD Sbjct: 25 KYLTDDIVKKYQATKTSLGGTLAQCVNTNAYNPGA--LLPRSC---DLNAYETFRDFFDA 79 Query: 92 VIEDRHGGYKPTDEH-KTDLNADNLQGGDDLDP--NYVLSSRVRTGRSIRGFCLPPHCSR 148 VI D H +H K++ DL+ N V+S+RVR GR++ GF P ++ Sbjct: 80 VIADYHKVPDGKIQHPKSNFGDLKSLSFTDLNTYGNLVVSTRVRLGRTVEGFGFGPTLTK 139 Query: 149 GERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASGMA 208 R +E AL +L G+ +G YY L M++ ++ +L++DHFLF + L A G Sbjct: 140 ETRIELENKISTALHNLSGEYEGTYYPLTGMSEEDRIKLVNDHFLFRNDDNVLRDAGGYI 199 Query: 209 RDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKN 268 DWP RGI+ N K FLVWINEEDH+RVISMQKGG + V+ R + ++ SK+ Sbjct: 200 -DWPTGRGIFINKQKNFLVWINEEDHIRVISMQKGGGLTAVYKRLADAIQEL-----SKS 253 Query: 269 YEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRLQKRGTGGVDTA 328 +F +N LG+I CPSNLGT LRA VH K+P L F E+ ++ +Q RGT G T Sbjct: 254 LKFAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQPRGTHGEHTE 313 Query: 329 AVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEK 369 +VGG++D+SN RLG +E++ V + GV+ L+E+E L++ Sbjct: 314 SVGGIYDLSNKRRLGLTELDAVTEMHSGVRALLELEVMLQE 354 >6FH2-A nrPDB Length = 366 Score = 90.9 bits (224), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 123/250 (49%), Gaps = 23/250 (9%) Query: 122 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALR--NM 179 + + VLSSR+R R+I F P S E + I L A G++ L+ + Sbjct: 24 NSDIVLSSRIRLARNIVDFRFPTLFSSEEAKQIVALFERAFVHRPYGEAGRFELLKMSEL 83 Query: 180 TDAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVIS 239 E++ L++ H L++ +A D P + ++N+ + INEEDH+R+ Sbjct: 84 QPIEKRVLVEKH----------LISPHLAEDSPFGACLL-SENEEISIMINEEDHIRIQC 132 Query: 240 MQKGGNMKEVFTRFCTGLTQIETLFKSK-NYEFMWNPHLGYILTCPSNLGTGLRAGVHIK 298 + G + E ++++ + NY F + LGY+ +CP+N+GTGLRA V + Sbjct: 133 LFPGLQLAEALE----AASELDDWIEGHVNYAF--DERLGYLTSCPTNVGTGLRASVMMH 186 Query: 299 LPNLGKHEKFGEV---LKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVD 355 LP L ++ + + +L L RGT G + A+G +F +SN LG SE ++V + Sbjct: 187 LPALVLTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVADLHT 246 Query: 356 GVKLLIEMEK 365 V+ LI E+ Sbjct: 247 IVEQLIAQER 256 >5O9X-A nrPDB Length = 549 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 253 FCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVL 312 LT E F + +FM P L Y++ C + LGT G + G +EK Sbjct: 145 LSAALTATEAEFI--DMKFMTTPQLHYVVRCKNTLGTQYEYG---EPTEQGYYEKLAAAF 199 Query: 313 KRLR--LQKRGTGGVDTA-AVGG 332 KR+ ++ +G+ VD A VGG Sbjct: 200 KRVMRGVKVKGSLTVDCANGVGG 222 >6D1P-A nrPDB Length = 814 Score = 28.5 bits (62), Expect = 4.9, Method: Compositional matrix adjust. Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 9/108 (8%) Query: 231 EEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNL--- 287 +E LRV S + KEV + LT+I + S +W+PH + TC + L Sbjct: 239 KEFSLRVFSPEG----KEV-NSISSELTEISSYQISLKRPQLWSPHSPALYTCVAELIDN 293 Query: 288 GTGLRAGVHIKLPNLGKHEKFGEVLKRLRLQKRGTG-GVDTAAVGGVF 334 G LR H + EK L RL RGT D A VG Sbjct: 294 GDTLRTTQHFGFRHFRFEEKGPFYLNGERLLLRGTHRHEDHAGVGAAL 341 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4Q2R-A nrPDB 652 0.0 1QH4-A nrPDB 644 0.0 1VRP-A nrPDB 642 0.0 1U6R-A nrPDB 641 0.0 1CRK-A nrPDB 591 e-169 4Z9M-A nrPDB 586 e-168 1QK1-A nrPDB 578 e-165 3L2D-A nrPDB 552 e-158 3JU6-A nrPDB 549 e-157 3JPZ-A nrPDB 538 e-153 4BG4-B nrPDB 508 e-144 5ZHQ-A nrPDB 506 e-144 5U8E-A nrPDB 499 e-141 4GVZ-A nrPDB 496 e-141 2J1Q-A nrPDB 487 e-138 4RF9-A nrPDB 475 e-134 4WO8-A nrPDB 447 e-126 6FH2-A nrPDB 265 3e-71 Sequences not found previously or not previously below threshold: 3I44-A nrPDB 30 2.1 3U1H-A nrPDB 30 2.5 5OGQ-A nrPDB 30 2.6 4I05-A nrPDB 29 3.1 4I04-A nrPDB 29 3.8 3SL2-A nrPDB 29 4.2 CONVERGED! >4Q2R-A nrPDB Length = 381 Score = 652 bits (1681), Expect = 0.0, Method: Composition-based stats. Identities = 345/381 (90%), Positives = 366/381 (96%) Query: 1 MPFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTG 60 MPFSNSHN LK+++ +DE+PDLS HNNHMAKVLT +LY +LR + T SGFT+DDVIQTG Sbjct: 1 MPFSNSHNTLKLRFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTG 60 Query: 61 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDD 120 VDNPGHP+IMTVGCVAGDEESY+VFKELFDP+IEDRHGGYKPTDEHKTDLN DNLQGGDD Sbjct: 61 VDNPGHPYIMTVGCVAGDEESYDVFKELFDPIIEDRHGGYKPTDEHKTDLNPDNLQGGDD 120 Query: 121 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMT 180 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKL+VEAL SL GDL G+YYAL++MT Sbjct: 121 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMT 180 Query: 181 DAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM 240 +AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM Sbjct: 181 EAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM 240 Query: 241 QKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP 300 QKGGNMKEVFTRFC GLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP Sbjct: 241 QKGGNMKEVFTRFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP 300 Query: 301 NLGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL 360 +LGKHEKF EVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL Sbjct: 301 HLGKHEKFPEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL 360 Query: 361 IEMEKRLEKGQSIDDLMPAQK 381 IEME+RLE+GQ+IDDLMPAQK Sbjct: 361 IEMEQRLEQGQAIDDLMPAQK 381 >1QH4-A nrPDB Length = 380 Score = 644 bits (1662), Expect = 0.0, Method: Composition-based stats. Identities = 380/380 (100%), Positives = 380/380 (100%) Query: 2 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV 61 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV Sbjct: 1 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV 60 Query: 62 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL 121 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL Sbjct: 61 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL 120 Query: 122 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD 181 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD Sbjct: 121 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD 180 Query: 182 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ 241 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ Sbjct: 181 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ 240 Query: 242 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN 301 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN Sbjct: 241 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN 300 Query: 302 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI 361 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI Sbjct: 301 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI 360 Query: 362 EMEKRLEKGQSIDDLMPAQK 381 EMEKRLEKGQSIDDLMPAQK Sbjct: 361 EMEKRLEKGQSIDDLMPAQK 380 >1VRP-A nrPDB Length = 381 Score = 642 bits (1655), Expect = 0.0, Method: Composition-based stats. Identities = 304/381 (79%), Positives = 341/381 (89%) Query: 1 MPFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTG 60 MPF N+HN K+ YS +E+PDLS HNNHMAK LTLD+YKKLRD++T SGFTLDD+IQTG Sbjct: 1 MPFGNTHNKWKLNYSAAEEFPDLSKHNNHMAKALTLDIYKKLRDKETPSGFTLDDIIQTG 60 Query: 61 VDNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDD 120 VDNPGHPFIMTVGCVAGDEE YEVFK+LFDPVIEDRHGGYKPTD+HKTDLN +NL+GGDD Sbjct: 61 VDNPGHPFIMTVGCVAGDEECYEVFKDLFDPVIEDRHGGYKPTDKHKTDLNQENLKGGDD 120 Query: 121 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMT 180 LDPNYVLSSRVRTGRSI+G LPPHCSRGERR +EKL ++ L +L G+ +GKYY L +M+ Sbjct: 121 LDPNYVLSSRVRTGRSIKGIALPPHCSRGERRLVEKLCIDGLATLTGEFQGKYYPLSSMS 180 Query: 181 DAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISM 240 DAEQQQLIDDHFLFDKP+SPLLLASGMARDWPD RGIWHN++KTFLVW+NEEDHLRVISM Sbjct: 181 DAEQQQLIDDHFLFDKPISPLLLASGMARDWPDGRGIWHNNDKTFLVWVNEEDHLRVISM 240 Query: 241 QKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLP 300 QKGGNMKEVF RFC GL +IE +F FMWN HLGY+LTCPSNLGTGLR GVH+K+P Sbjct: 241 QKGGNMKEVFRRFCVGLKKIEDIFVKAGRGFMWNEHLGYVLTCPSNLGTGLRGGVHVKIP 300 Query: 301 NLGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLL 360 +L KHEKF EVLKR RLQKRGTGGVDTAAVG ++D+SNADRLGFSEVE VQMVVDGVKL+ Sbjct: 301 HLCKHEKFSEVLKRTRLQKRGTGGVDTAAVGSIYDISNADRLGFSEVEQVQMVVDGVKLM 360 Query: 361 IEMEKRLEKGQSIDDLMPAQK 381 +EMEKRLE G+SIDDLMPAQK Sbjct: 361 VEMEKRLENGKSIDDLMPAQK 381 >1U6R-A nrPDB Length = 380 Score = 641 bits (1654), Expect = 0.0, Method: Composition-based stats. Identities = 306/380 (80%), Positives = 345/380 (90%) Query: 2 PFSNSHNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGV 61 PF N+HN K+ Y ++EYPDLS HNNHMAKVLT DLYKKLRD++T SGFTLDDVIQTGV Sbjct: 1 PFGNTHNKYKLNYKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTGV 60 Query: 62 DNPGHPFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDL 121 DNPGHPFIMTVGCVAGDEESY VFK+LFDP+I+DRHGG+KPTD+HKTDLN +NL+GGDDL Sbjct: 61 DNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDDL 120 Query: 122 DPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTD 181 DP+YVLSSRVRTG+SI+G+ LPPHCSRGERRA+EKLSVEAL SL G+ KGKYY L++MT+ Sbjct: 121 DPHYVLSSRVRTGKSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTE 180 Query: 182 AEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQ 241 EQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNK+FLVW+NEEDHLRVISM+ Sbjct: 181 QEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISME 240 Query: 242 KGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPN 301 KGGNMKEVF RFC GL +IE +FK + FMWN HLGY+LTCPSNLGTGLR GVH+KL + Sbjct: 241 KGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAH 300 Query: 302 LGKHEKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLI 361 L KH KF E+L RLRLQKRGTGGVDTAAVG VFD+SNADRLG SEVE VQ+VVDGVKL++ Sbjct: 301 LSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDISNADRLGSSEVEQVQLVVDGVKLMV 360 Query: 362 EMEKRLEKGQSIDDLMPAQK 381 EMEK+LEKGQSIDD++PAQK Sbjct: 361 EMEKKLEKGQSIDDMIPAQK 380 >1CRK-A nrPDB Length = 380 Score = 591 bits (1524), Expect = e-169, Method: Composition-based stats. Identities = 248/368 (67%), Positives = 290/368 (78%), Gaps = 3/368 (0%) Query: 7 HNLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGH 66 H K+ + +YPDL HNN MA+ LT +Y KLRD+ T +G++LD IQTGVDNPGH Sbjct: 3 HEKRKL-FPPSADYPDLRKHNNCMAECLTPAIYAKLRDKLTPNGYSLDQCIQTGVDNPGH 61 Query: 67 PFIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNY 125 PFI TVG VAGDEESYEVF E+FDPVI+ RH GY P T +H TDL+A + G D Y Sbjct: 62 PFIKTVGMVAGDEESYEVFAEIFDPVIKARHNGYDPRTMKHHTDLDASKITHGQ-FDERY 120 Query: 126 VLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQ 185 VLSSRVRTGRSIRG LPP CSR ERR +E + V AL L GDL GKYY+L NM++ +QQ Sbjct: 121 VLSSRVRTGRSIRGLSLPPACSRAERREVENVVVTALAGLKGDLSGKYYSLTNMSERDQQ 180 Query: 186 QLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGN 245 QLIDDHFLFDKPVSPLL +GMARDWPDARGIWHN++KTFLVWINEEDH RVISM+KGGN Sbjct: 181 QLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNNDKTFLVWINEEDHTRVISMEKGGN 240 Query: 246 MKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKH 305 MK VF RFC GL ++E L K + +EFMWN LGY+LTCPSNLGTGLRAGVH+KLP L K Sbjct: 241 MKRVFERFCRGLKEVERLIKERGWEFMWNERLGYVLTCPSNLGTGLRAGVHVKLPRLSKD 300 Query: 306 EKFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEK 365 +F ++L+ LRLQKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ EK Sbjct: 301 PRFPKILENLRLQKRGTGGVDTAAVADVYDISNLDRMGRSEVELVQIVIDGVNYLVDCEK 360 Query: 366 RLEKGQSI 373 +LEKGQ I Sbjct: 361 KLEKGQDI 368 >4Z9M-A nrPDB Length = 392 Score = 586 bits (1511), Expect = e-168, Method: Composition-based stats. Identities = 237/361 (65%), Positives = 285/361 (78%), Gaps = 2/361 (0%) Query: 14 YSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVG 73 + +YPDL HNN MA+ LT +Y KLR++ T +G+TLD IQTGVDNPGHPFI TVG Sbjct: 24 FPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVG 83 Query: 74 CVAGDEESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVR 132 VAGDEESYEVF +LFDPVI+ RH GY P +H TDL+A + G D +YVLSSRVR Sbjct: 84 MVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQ-FDEHYVLSSRVR 142 Query: 133 TGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHF 192 TGRSIRG LPP C+R ERR +E +++ AL L GDL G+YY L MT+ +QQ+LIDDHF Sbjct: 143 TGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHF 202 Query: 193 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 252 LFDKPVSPLL +GMARDWPDARGIWHN +KTFL+WINEEDH RVISM+KGGNMK VF R Sbjct: 203 LFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFER 262 Query: 253 FCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVL 312 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVH+++P L K +F ++L Sbjct: 263 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKIL 322 Query: 313 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQS 372 + LRLQKRGTGGVDTAAV V+D+SN DR+G SEVELVQ+V+DGV L++ EK+LE+GQ Sbjct: 323 ENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQD 382 Query: 373 I 373 I Sbjct: 383 I 383 >1QK1-A nrPDB Length = 379 Score = 578 bits (1490), Expect = e-165, Method: Composition-based stats. Identities = 248/361 (68%), Positives = 289/361 (80%), Gaps = 2/361 (0%) Query: 14 YSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVG 73 Y EYPDL HNN MA LT +Y +L D+ T +G+TLD IQTGVDNPGHPFI TVG Sbjct: 9 YPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPFIKTVG 68 Query: 74 CVAGDEESYEVFKELFDPVIEDRHGGYKP-TDEHKTDLNADNLQGGDDLDPNYVLSSRVR 132 VAGDEE+YEVF +LFDPVI++RH GY P T +H TDL+A ++ G D YVLSSRVR Sbjct: 69 MVAGDEETYEVFADLFDPVIQERHNGYDPRTMKHTTDLDASKIRSGY-FDERYVLSSRVR 127 Query: 133 TGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHF 192 TGRSIRG LPP C+R ERR +E++ V+AL L GDL G+YY L MT+AEQQQLIDDHF Sbjct: 128 TGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHF 187 Query: 193 LFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTR 252 LFDKPVSPLL A+GMARDWPDARGIWHN+ K+FL+W+NEEDH RVISM+KGGNMK VF R Sbjct: 188 LFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFER 247 Query: 253 FCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVL 312 FC GL ++E L + + +EFMWN LGYILTCPSNLGTGLRAGVHIKLP L K +F ++L Sbjct: 248 FCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKDSRFPKIL 307 Query: 313 KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQS 372 + LRLQKRGTGGVDTAA GGVFD+SN DRLG SEVELVQ+V+DGV LI+ E+RLE+GQ Sbjct: 308 ENLRLQKRGTGGVDTAATGGVFDISNLDRLGKSEVELVQLVIDGVNYLIDCERRLERGQD 367 Query: 373 I 373 I Sbjct: 368 I 368 >3L2D-A nrPDB Length = 390 Score = 552 bits (1423), Expect = e-158, Method: Composition-based stats. Identities = 208/368 (56%), Positives = 259/368 (70%), Gaps = 4/368 (1%) Query: 13 KYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFI-MT 71 K+ D +PDLS HNN MA LT +LY+K D+ T +G T D IQTGVDNPG+ F Sbjct: 24 KFKAADNFPDLSKHNNVMASQLTKELYEKYWDKVTPNGVTFDKCIQTGVDNPGNKFYGKK 83 Query: 72 VGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHK-TDLNADNLQGGDDLDPNYVLSSR 130 GCV GDE SYE +KE FD IE+ H +KP+D+H DL+ + L GG + YV S R Sbjct: 84 TGCVFGDEYSYECYKEFFDKCIEEIHH-FKPSDKHPAPDLDHNKLVGGV-FEDKYVKSCR 141 Query: 131 VRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDD 190 +R GRS++G CLPP SR ERR +EK+ +ALG L GDL GKYY L M + +Q+QLI+D Sbjct: 142 IRCGRSVKGVCLPPAMSRAERRLVEKVVSDALGGLKGDLAGKYYPLTTMNEKDQEQLIED 201 Query: 191 HFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVF 250 HFLF+KP LL SG ARDWPD RGIWHN+ K FLVWINEEDH+RVISMQKGG++K VF Sbjct: 202 HFLFEKPTGALLTTSGCARDWPDGRGIWHNNEKNFLVWINEEDHIRVISMQKGGDLKAVF 261 Query: 251 TRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGE 310 +RF GL ++E L K + M N LGYI TCP+N+GT +RA VH++L L KH +F E Sbjct: 262 SRFARGLLEVERLMKECGHGLMHNDRLGYICTCPTNMGTVVRASVHLRLAFLEKHPRFDE 321 Query: 311 VLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKG 370 +L +LRL KRGTGG + A +D+SN RLG SE ELVQ++VDGV LLI +K+LE G Sbjct: 322 MLGKLRLGKRGTGGESSLATDSTYDISNWARLGKSERELVQVLVDGVNLLIACDKKLEAG 381 Query: 371 QSIDDLMP 378 QSIDD++P Sbjct: 382 QSIDDMIP 389 >3JU6-A nrPDB Length = 370 Score = 549 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 230/372 (61%), Positives = 276/372 (74%), Gaps = 6/372 (1%) Query: 8 NLLKMKYSVDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHP 67 NL + KY D++P+ H + ++K LT D+Y KLRD T SG+TLD IQ GVDNP Sbjct: 3 NLNQKKYPAKDDFPNFEGHKSLLSKYLTADMYAKLRDVATPSGYTLDRAIQNGVDNP--- 59 Query: 68 FIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGDDLDPNYVL 127 +G +AGDEE+Y VF +LFDPVIE+ H G+K TD HKTDL+A + D LDP YV+ Sbjct: 60 -DFHLGLLAGDEETYTVFADLFDPVIEEYHNGFKKTDNHKTDLDASKILD-DVLDPAYVI 117 Query: 128 SSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQL 187 SSRVRTGR+IRG L PH R ERRAIEK+ EAL SL DLKGKYY+L M + QQQL Sbjct: 118 SSRVRTGRNIRGMALSPHVCRSERRAIEKMVSEALNSLAADLKGKYYSLMKMDEKTQQQL 177 Query: 188 IDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMK 247 IDDHFLFD+PVS + GMARD+PD RGIWHND K FLVWINEEDH R+ISMQ GGNMK Sbjct: 178 IDDHFLFDRPVSRHFTSGGMARDFPDGRGIWHNDKKNFLVWINEEDHTRIISMQMGGNMK 237 Query: 248 EVFTRFCTGLTQIETLFKSK-NYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHE 306 EVF RF GLT++E K K EFM N HLG++LTCPSNLGTG+R VH KLP++ K + Sbjct: 238 EVFERFTRGLTEVEKHIKDKTGKEFMKNDHLGFVLTCPSNLGTGVRCSVHAKLPHMAKDK 297 Query: 307 KFGEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKR 366 +F E+ ++RLQKRGT G T +VGGV+D+SN DRLG SEVE V V+ GVK+LIEMEK+ Sbjct: 298 RFEEICTKMRLQKRGTSGEFTESVGGVYDISNLDRLGSSEVEQVNCVIKGVKVLIEMEKK 357 Query: 367 LEKGQSIDDLMP 378 LEKG+SIDDL+P Sbjct: 358 LEKGESIDDLVP 369 >3JPZ-A nrPDB Length = 366 Score = 538 bits (1387), Expect = e-153, Method: Composition-based stats. Identities = 202/365 (55%), Positives = 251/365 (68%), Gaps = 6/365 (1%) Query: 16 VDDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCV 75 +PD + H + + L ++Y++L ++T+ G T+D VIQ VDN G+ +G + Sbjct: 7 AKANFPDYANHGCVVGRHLNFEMYQRLFGKKTAHGVTVDKVIQPSVDNFGN----CIGLI 62 Query: 76 AGDEESYEVFKELFDPVIEDRHGGYKPTDEHK-TDLNADNLQGGDDLDPNYVLSSRVRTG 134 AGDEESYEVFKELFD VI ++H G+ P D DL+A L GG D YV S R+RTG Sbjct: 63 AGDEESYEVFKELFDAVINEKHKGFGPNDSQPAPDLDASKLVGGQ-FDEKYVKSCRIRTG 121 Query: 135 RSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLF 194 R IRG C PP C+RGERR +E++ AL L GDL G YY L MT ++ QLI DHFLF Sbjct: 122 RGIRGLCYPPSCTRGERREVERVITTALAGLSGDLSGTYYPLSKMTPEQENQLIADHFLF 181 Query: 195 DKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFC 254 KP L++ S RDWPDARGIWHN+ KTFL+WINEEDH+RVISMQKGGN+K VF RF Sbjct: 182 QKPTGHLMVNSASVRDWPDARGIWHNNEKTFLIWINEEDHMRVISMQKGGNVKAVFERFG 241 Query: 255 TGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKR 314 GL I K E+MWN LGY+ CPSNLGTGLRA VH++L L KH KF +++ Sbjct: 242 RGLNAIAEQMKKNGREYMWNQRLGYLCACPSNLGTGLRASVHVQLHQLSKHPKFEDIVVA 301 Query: 315 LRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEKGQSID 374 L+LQKRGTGG TAAV V+D+SNA RL SE E VQ+++DGVK LI+ME+ LE G+SID Sbjct: 302 LQLQKRGTGGEHTAAVDDVYDISNAARLKKSEREFVQLLIDGVKKLIDMEQALEAGKSID 361 Query: 375 DLMPA 379 DL+PA Sbjct: 362 DLIPA 366 >4BG4-B nrPDB Length = 356 Score = 508 bits (1309), Expect = e-144, Method: Composition-based stats. Identities = 157/343 (45%), Positives = 214/343 (62%), Gaps = 12/343 (3%) Query: 27 NNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFK 86 + + K LT D++ KL+D++TS G TL DVIQ+GV+N VG A D E+Y +F Sbjct: 24 RSLLKKYLTKDVFDKLKDKKTSLGATLLDVIQSGVEN----LDSGVGIYAPDAEAYTLFA 79 Query: 87 ELFDPVIEDRHGGYKPTDEHK-TDLNADNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPH 145 LFDP+IED H G+K TD+H D N D + +V+S+RVR GRS++G+ P Sbjct: 80 PLFDPIIEDYHVGFKQTDKHPNKDFGDVNSFVNVDPEGKFVISTRVRCGRSMQGYPFNPC 139 Query: 146 CSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLAS 205 + + + +E L SL G+LKG YY L M+ QQ+LIDDHFLF K L A+ Sbjct: 140 LTESQYKEMEAKVSSTLSSLEGELKGTYYPLTGMSKEVQQKLIDDHFLF-KEGDRFLQAA 198 Query: 206 GMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFK 265 R WP RGI+HNDNKTFLVW+NEEDHLR+ISMQ GG++ +VF R + + +IE Sbjct: 199 NACRYWPAGRGIYHNDNKTFLVWVNEEDHLRIISMQMGGDLGQVFRRLTSAVNEIE---- 254 Query: 266 SKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKH-EKFGEVLKRLRLQKRGTGG 324 K F + LG++ CP+NLGT +RA VHIKLP L + EK EV + LQ RGT G Sbjct: 255 -KRIPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYNLQVRGTRG 313 Query: 325 VDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRL 367 T A GG++D+SN R+G +E + V+ + DG+ LI++EK + Sbjct: 314 EHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEM 356 >5ZHQ-A nrPDB Length = 357 Score = 506 bits (1304), Expect = e-144, Method: Composition-based stats. Identities = 154/344 (44%), Positives = 211/344 (61%), Gaps = 12/344 (3%) Query: 27 NNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFK 86 + + K LT ++ +L+ ++TS G TL DVIQ+GV+N VG A D E+Y +F Sbjct: 24 KSLLKKYLTKSVFDQLKGKKTSLGATLLDVIQSGVEN----LDSGVGVYAPDAEAYTLFA 79 Query: 87 ELFDPVIEDRHGGYKPTDEHK-TDLNADNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPH 145 LFDP+IED H G+K TD+H D N D D +V+S+RVR GRS+ G+ P Sbjct: 80 PLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCGRSMEGYPFNPC 139 Query: 146 CSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLAS 205 + + + +E L +L G+LKG YY L MT QQ+LIDDHFLF K L A+ Sbjct: 140 LTEAQYKEMESKVSSTLSNLEGELKGTYYPLTGMTKDVQQKLIDDHFLF-KEGDRFLQAA 198 Query: 206 GMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFK 265 R WP RGI+HNDNKTFLVW +EEDHLR+ISMQ GG++ +V+ R + + +IE Sbjct: 199 NACRYWPTGRGIYHNDNKTFLVWCDEEDHLRIISMQMGGDLGQVYRRLVSAVNEIE---- 254 Query: 266 SKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKH-EKFGEVLKRLRLQKRGTGG 324 K F + LG++ CP+NLGT +RA VHIKLP L + EK EV + LQ RGT G Sbjct: 255 -KRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYSLQVRGTRG 313 Query: 325 VDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLE 368 T A GGV+D+SN R+G +E + V+ + DG+ LI++EK ++ Sbjct: 314 EHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ 357 >5U8E-A nrPDB Length = 384 Score = 499 bits (1284), Expect = e-141, Method: Composition-based stats. Identities = 147/347 (42%), Positives = 205/347 (59%), Gaps = 12/347 (3%) Query: 22 DLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEES 81 D + + + K L +++ + + +T+ G TL D IQ+GV+N VG A D E+ Sbjct: 46 DATDCKSLLKKYLNREVFDQCKSLKTALGATLLDCIQSGVEN----LDSGVGIYAPDAEA 101 Query: 82 YEVFKELFDPVIEDRHGGYKPTDEHK-TDLNADNLQGGDDLDPNYVLSSRVRTGRSIRGF 140 Y +F +F+P+IED H G+KPTD+H TD N D YV+S+ VR GRS++G+ Sbjct: 102 YTLFAPIFNPIIEDYHEGFKPTDKHPPTDFGDINTIVNVDPSGKYVVSTHVRCGRSLKGY 161 Query: 141 CLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSP 200 P + + +E G+ G+LKGKYY L M A QQQLIDDHFLF K Sbjct: 162 PFNPCLTEANYKEMEDKVSAIFGTFEGELKGKYYPLTGMDKATQQQLIDDHFLF-KEGDR 220 Query: 201 LLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQI 260 L A+ R WP RGI+HND KTFLVW+NEEDHLR+ISMQKGG++K +F R + I Sbjct: 221 FLQAANACRYWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGDLKTIFQRLVNAVNTI 280 Query: 261 ETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEK-FGEVLKRLRLQK 319 E+ F + LG++ CP+NLGT +RA VHI LP L K +K + + LQ Sbjct: 281 ES-----KLPFSRDDRLGFLTFCPTNLGTTIRASVHIALPKLAKDKKQLEAIAAKFNLQV 335 Query: 320 RGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKR 366 RGT G T + GGV+D+SN R+G +E + V+ + DG+ +I+ME+ Sbjct: 336 RGTRGEHTESEGGVYDISNKRRMGLTEYQAVKEMQDGILEMIKMEEA 382 >4GVZ-A nrPDB Length = 357 Score = 496 bits (1278), Expect = e-141, Method: Composition-based stats. Identities = 150/342 (43%), Positives = 208/342 (60%), Gaps = 12/342 (3%) Query: 27 NNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFK 86 + + K LT D++ +++++T G TL DVIQ+GV+N VG A D ESY F Sbjct: 24 KSLLKKHLTKDVFDSIKNKKTGMGATLLDVIQSGVEN----LDSGVGIYAPDAESYRTFG 79 Query: 87 ELFDPVIEDRHGGYKPTDEHKTDLNAD-NLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPH 145 LFDP+I+D HGG+K TD+H D N G D +++S+RVR GRS++G+ P Sbjct: 80 PLFDPIIDDYHGGFKLTDKHPPKQWGDINTLVGLDPAGQFIISTRVRCGRSLQGYPFNPC 139 Query: 146 CSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLAS 205 + + + +E+ L S+ +LKG YY L M+ A QQQLIDDHFLF K L + Sbjct: 140 LTAEQYKEMEEKVSSTLSSMEDELKGTYYPLTGMSKATQQQLIDDHFLF-KEGDRFLQTA 198 Query: 206 GMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFK 265 R WP RGI+HND KTFLVW+NEEDHLR+ISMQKGG++K V+ R T + IE+ Sbjct: 199 NACRYWPTGRGIFHNDAKTFLVWVNEEDHLRIISMQKGGDLKTVYKRLVTAVDNIES--- 255 Query: 266 SKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEK-FGEVLKRLRLQKRGTGG 324 F + G++ CP+NLGT +RA VHI+LP L K K ++ + LQ RGT G Sbjct: 256 --KLPFSHDDRFGFLTFCPTNLGTTMRASVHIQLPKLAKDRKVLEDIASKFNLQVRGTRG 313 Query: 325 VDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKR 366 T + GGV+D+SN RLG +E + V+ + DG+ +I+MEK Sbjct: 314 EHTESEGGVYDISNKRRLGLTEYQAVREMQDGILEMIKMEKA 355 >2J1Q-A nrPDB Length = 357 Score = 487 bits (1253), Expect = e-138, Method: Composition-based stats. Identities = 157/340 (46%), Positives = 208/340 (61%), Gaps = 12/340 (3%) Query: 28 NHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKE 87 + + K LT +++ +L+ +QT G TL DVIQ+GV+N +G A D ESY +F Sbjct: 25 SLLKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVEN----LDSGIGVYAPDAESYTLFAA 80 Query: 88 LFDPVIEDRHGGYKPTDEHKTDLNAD-NLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHC 146 L DP+IED H G+KP+D+ + D N D D YV+S+RVR GRS+ G+ P Sbjct: 81 LLDPIIEDYHKGFKPSDKQPPKDSGDLNTFIDVDPDKKYVISTRVRCGRSLEGYPFNPCL 140 Query: 147 SRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSPLLLASG 206 + + +E L S+ G+L+GKYY L MT Q+QLIDDHFLF K L A+ Sbjct: 141 KKQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLIDDHFLF-KEGDRFLQAAH 199 Query: 207 MARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKS 266 + WP RGI+HND KTFLVW+NEEDHLR+ISMQKGGN+KEVF R T + IE K Sbjct: 200 ACKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKEVFGRLVTAVGVIEEKVK- 258 Query: 267 KNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKH-EKFGEVLKRLRLQKRGTGGV 325 F + LG++ CP+NLGT +RA VHIKLP LG +K EV + LQ RGT G Sbjct: 259 ----FSRDDRLGFLTFCPTNLGTTIRASVHIKLPKLGADRKKLEEVAAKYNLQVRGTAGE 314 Query: 326 DTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEK 365 + + GV+D+SN RLG SE E V+ + DG+ LI+ E+ Sbjct: 315 HSDSPDGVYDISNKRRLGLSEYEAVKEMQDGILELIKAEE 354 >4RF9-A nrPDB Length = 718 Score = 475 bits (1222), Expect = e-134, Method: Composition-based stats. Identities = 158/371 (42%), Positives = 227/371 (61%), Gaps = 20/371 (5%) Query: 13 KYSVDDEYPDLSVH-----NNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHP 67 K+ + +PD + + K LT +++ L++++T G TL D I +GV N Sbjct: 12 KFKSKNAFPDPLNDPKCNPKSLVKKYLTPKVFESLKNKKTKLGITLWDCINSGVVN---- 67 Query: 68 FIMTVGCVAGDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQGGD-DLDPNYV 126 VG AGDEESY +F LFD +IED H YK H +D+N +++ D D Y+ Sbjct: 68 LDSGVGVYAGDEESYTLFGPLFDAIIEDYHSPYKLATGHNSDMNPAHVKAPDLDPANRYI 127 Query: 127 LSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQ 186 S+R+R RS++G+ L P ++ R IEK V L SL GDL GKYY L M + +QQ Sbjct: 128 RSTRIRVARSLKGYGLAPGVTKAHRLEIEKKVVGVLTSLTGDLAGKYYPLSGMDEKTRQQ 187 Query: 187 LIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNM 246 L+DDHFLF K L A+G+ ++WP+ RGI+HN++KTFLVW+NEEDHLR+ISM+KG ++ Sbjct: 188 LVDDHFLFKK-GDRFLEAAGINKEWPEGRGIYHNNDKTFLVWLNEEDHLRIISMEKGSDI 246 Query: 247 KEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHE 306 VF+R C + +I+ K F GY+ +CPSNLGTG+RA VH+K+P+ +H Sbjct: 247 GSVFSRLCRAVNEID-----KKLGFQHTKKHGYLTSCPSNLGTGMRASVHVKIPHAKEHP 301 Query: 307 KFGEVLKRLRLQKRGTGGVDTAAVG---GVFDVSNADRLGFSEVELVQMVVDGVKLLIEM 363 F +L + +Q RG G + + G GV+D+SN RLG SEV+ VQ + DGVK L+E+ Sbjct: 302 DFENILTKYHIQARGIHGEHSESTGEDAGVYDISNRRRLGLSEVQCVQDMYDGVKALMEL 361 Query: 364 EKR-LEKGQSI 373 EK + K +S+ Sbjct: 362 EKEAIAKKRSV 372 Score = 443 bits (1139), Expect = e-125, Method: Composition-based stats. Identities = 147/353 (41%), Positives = 218/353 (61%), Gaps = 17/353 (4%) Query: 20 YPDLSVH---NNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVA 76 +P++ + + + K LT +L+ L+D++T+ G +L D I +GV+N + G A Sbjct: 373 FPEVLKNPEVKSLLRKYLTPELFDSLKDKKTAKGISLYDCINSGVEN----LDSSCGVYA 428 Query: 77 GDEESYEVFKELFDPVIEDRHGGYKPTDEHKTDLNADNLQG-GDDLDPNYVLSSRVRTGR 135 GDEE Y +F LFD ++ED H YK ++H +D+N + + D + Y+ S+R+R R Sbjct: 429 GDEECYTLFAPLFDKIVEDYHSPYKLANKHTSDMNPEKVDAPNLDPEGTYIRSTRIRVAR 488 Query: 136 SIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFD 195 +++G+ L P +R ER IE+ V L SL GDL G+YY L M +A +Q+L++DHFLF Sbjct: 489 NVKGYALTPGLTRNERLDIERKVVGVLSSLTGDLAGQYYPLTGMDEATRQKLVNDHFLFK 548 Query: 196 KPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCT 255 K L A+G+ + WP+ RGI+HN++KTFLVWINEED LR+ISM+KG ++ VF R C Sbjct: 549 K-GDRFLEAAGVNKLWPEGRGIFHNNDKTFLVWINEEDQLRIISMEKGSDIGSVFGRLCR 607 Query: 256 GLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRL 315 + +I+ K F GY+ CP+NLGTG+RA VH+K+P H F ++ Sbjct: 608 AVNEID-----KQLGFQHTDAHGYLSGCPTNLGTGMRASVHVKIPKASAHPDFQKICDEF 662 Query: 316 RLQKRGTGGVDTAAVG---GVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEK 365 +Q RG G + + G GVFD+SN RLG SEV+ VQ + +GVK L+E+EK Sbjct: 663 HIQARGIHGEHSVSTGEDAGVFDISNRRRLGLSEVQCVQDMYNGVKKLLEIEK 715 >4WO8-A nrPDB Length = 716 Score = 447 bits (1149), Expect = e-126, Method: Composition-based stats. Identities = 134/348 (38%), Positives = 197/348 (56%), Gaps = 15/348 (4%) Query: 24 SVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYE 83 S+ + K LT ++ KK ++T+ G TL +I+ G N ++ G+ E Y Sbjct: 380 SIEKCYTRKYLTPEIIKKYDGKRTTHGATLAHMIRNGAYNN-----RSICPRTGEAECYS 434 Query: 84 VFKELFDPVIEDRHGGYKPTDEHKTDLNAD--NLQGGD-DLDPNYVLSSRVRTGRSIRGF 140 F + DP+I D HG +H D L GD D +++S+RVR GRS+ GF Sbjct: 435 TFIDYLDPLICDYHGVKDSAFKHPAPTFGDLSKLPFGDLDPTGKFIVSTRVRVGRSVEGF 494 Query: 141 CLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPVSP 200 P S+ +R +E++ AL L G+ G YY L +M + +++QL++DHFLF K P Sbjct: 495 LFPTIMSKTDRIKLEQVISGALKGLTGEHAGTYYPLTDMKEEDRKQLVEDHFLF-KNDDP 553 Query: 201 LLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQI 260 +L +G RDWP RGI+HN++KTFLVW+ EEDH+R+ISMQ+GGN+ V+ R G+ I Sbjct: 554 VLRDAGGYRDWPVGRGIFHNNSKTFLVWVCEEDHMRIISMQQGGNLAAVYKRLIEGINAI 613 Query: 261 ETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHE-KFGEVLKRLRLQK 319 K+ +F + GYI CPSNLGT +RA V +K+P L K E+ + LQ Sbjct: 614 -----GKSMKFAHSDKYGYITCCPSNLGTSMRASVLLKIPKLSSQPKKLDEICAKYMLQA 668 Query: 320 RGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRL 367 RG G T + G +D+SN RLG +E++ + +GV +IE+EK L Sbjct: 669 RGLYGEHTESPDGTYDISNKRRLGLTELQAAHEMAEGVAKMIEIEKGL 716 Score = 376 bits (965), Expect = e-104, Method: Composition-based stats. Identities = 136/351 (38%), Positives = 198/351 (56%), Gaps = 15/351 (4%) Query: 22 DLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEES 81 D H + K LT D+ KK + +TS G TL + T NPG + D + Sbjct: 16 DERNH-SLTKKYLTDDIVKKYQATKTSLGGTLAQCVNTNAYNPGALLPRSC-----DLNA 69 Query: 82 YEVFKELFDPVIEDRHGGYKPTDEHK-TDLNADNLQGGDDLD--PNYVLSSRVRTGRSIR 138 YE F++ FD VI D H +H ++ DL+ N V+S+RVR GR++ Sbjct: 70 YETFRDFFDAVIADYHKVPDGKIQHPKSNFGDLKSLSFTDLNTYGNLVVSTRVRLGRTVE 129 Query: 139 GFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYALRNMTDAEQQQLIDDHFLFDKPV 198 GF P ++ R +E AL +L G+ +G YY L M++ ++ +L++DHFLF + Sbjct: 130 GFGFGPTLTKETRIELENKISTALHNLSGEYEGTYYPLTGMSEEDRIKLVNDHFLF-RND 188 Query: 199 SPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLT 258 +L +G DWP RGI+ N K FLVWINEEDH+RVISMQKGG + V+ R + Sbjct: 189 DNVLRDAGGYIDWPTGRGIFINKQKNFLVWINEEDHIRVISMQKGGGLTAVYKRLADAIQ 248 Query: 259 QIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFGEVLKRLRLQ 318 ++ SK+ +F +N LG+I CPSNLGT LRA VH K+P L F E+ ++ +Q Sbjct: 249 EL-----SKSLKFAFNDRLGFITFCPSNLGTTLRASVHAKIPMLASLPNFKEICEKHGIQ 303 Query: 319 KRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEKRLEK 369 RGT G T +VGG++D+SN RLG +E++ V + GV+ L+E+E L++ Sbjct: 304 PRGTHGEHTESVGGIYDLSNKRRLGLTELDAVTEMHSGVRALLELEVMLQE 354 >6FH2-A nrPDB Length = 366 Score = 265 bits (677), Expect = 3e-71, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 122/252 (48%), Gaps = 23/252 (9%) Query: 121 LDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLSVEALGSLGGDLKGKYYAL--RN 178 + + VLSSR+R R+I F P S E + I L A G++ L Sbjct: 23 PNSDIVLSSRIRLARNIVDFRFPTLFSSEEAKQIVALFERAFVHRPYGEAGRFELLKMSE 82 Query: 179 MTDAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVI 238 + E++ L++ H L++ +A D P + ++N+ + INEEDH+R+ Sbjct: 83 LQPIEKRVLVEKH----------LISPHLAEDSPFGACLL-SENEEISIMINEEDHIRIQ 131 Query: 239 SMQKGGNMKEVFTRFCTGLTQIETLFKSK-NYEFMWNPHLGYILTCPSNLGTGLRAGVHI 297 + G + E ++++ + NY F + LGY+ +CP+N+GTGLRA V + Sbjct: 132 CLFPGLQLAEALE----AASELDDWIEGHVNYAF--DERLGYLTSCPTNVGTGLRASVMM 185 Query: 298 KLPNLGKHEKFGEVL---KRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVV 354 LP L ++ ++ +L L RGT G + A+G +F +SN LG SE ++V + Sbjct: 186 HLPALVLTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVADLH 245 Query: 355 DGVKLLIEMEKR 366 V+ LI E+ Sbjct: 246 TIVEQLIAQERA 257 >3I44-A nrPDB Length = 497 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 27/66 (40%), Gaps = 15/66 (22%) Query: 27 NNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESY---- 82 NH+ V++ + Y K++ D+IQ+G+D G G E Y Sbjct: 339 GNHIGPVVSKEQYDKIQ-----------DLIQSGIDEGATLVTGGTGLPMGMERGYYVRP 387 Query: 83 EVFKEL 88 VF ++ Sbjct: 388 TVFADV 393 >3U1H-A nrPDB Length = 390 Score = 29.6 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 5/48 (10%) Query: 148 RGERRAIEKLSVEALGS--LGGDLK---GKYYALRNMTDAEQQQLIDD 190 E +AIEK + L D+ GKY + MTD + ++D+ Sbjct: 332 EEEAKAIEKAVEKVLAEGYRTADIAKPGGKYVSTTEMTDEVKAAVVDE 379 >5OGQ-A nrPDB Length = 254 Score = 29.6 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 24/91 (26%), Gaps = 13/91 (14%) Query: 2 PFSNSHNLLKMKYSV--DDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQT 59 PF + K KY Y K T K R + + + Sbjct: 105 PFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYN---------- 154 Query: 60 GVDNPGHPFIMTVGCVAGDEESYEVFKELFD 90 V N + E + V+++ + Sbjct: 155 -VKNDEKAIQKEIMKYGPVEAGFTVYEDFLN 184 >4I05-A nrPDB Length = 285 Score = 29.2 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 24/91 (26%), Gaps = 13/91 (14%) Query: 2 PFSNSHNLLKMKYSV--DDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQT 59 PF + K KY Y K T K R + + + Sbjct: 136 PFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYN---------- 185 Query: 60 GVDNPGHPFIMTVGCVAGDEESYEVFKELFD 90 V N + E + V+++ + Sbjct: 186 -VKNDEKAIQKEIMKYGPVEAGFTVYEDFLN 215 >4I04-A nrPDB Length = 323 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 24/91 (26%), Gaps = 13/91 (14%) Query: 2 PFSNSHNLLKMKYSV--DDEYPDLSVHNNHMAKVLTLDLYKKLRDRQTSSGFTLDDVIQT 59 PF + K KY Y K T K R + + + Sbjct: 174 PFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYN---------- 223 Query: 60 GVDNPGHPFIMTVGCVAGDEESYEVFKELFD 90 V N + E + V+++ + Sbjct: 224 -VKNDEKAIQKEIMKYGPVEAGFTVYEDFLN 253 >3SL2-A nrPDB Length = 177 Score = 28.8 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 27/74 (36%), Gaps = 12/74 (16%) Query: 205 SGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGG------NMKEVFTRFCTGLT 258 S + P+ + TF + +NEE+ L IS++ G ++++VF RF Sbjct: 53 SNALKYSPEGGHV------TFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFYRVDK 106 Query: 259 QIETLFKSKNYEFM 272 Sbjct: 107 ARTRKLGGTGLGLA 120 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.141 0.399 Lambda K H 0.267 0.0431 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,050,673 Number of Sequences: 36641 Number of extensions: 692861 Number of successful extensions: 1779 Number of sequences better than 10.0: 25 Number of HSP's better than 10.0 without gapping: 37 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 1626 Number of HSP's gapped (non-prelim): 50 length of query: 381 length of database: 10,336,785 effective HSP length: 99 effective length of query: 282 effective length of database: 6,709,326 effective search space: 1892029932 effective search space used: 1892029932 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.6 bits)