BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P05089 (322 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3LP4-A nrPDB 651 0.0 5RLA-A nrPDB 574 e-164 1PQ3-A nrPDB 400 e-112 5YNL-A nrPDB 277 4e-75 4Q3T-A nrPDB 256 1e-68 1CEV-A nrPDB 237 5e-63 4ITY-A nrPDB 235 2e-62 6DKT-A nrPDB 224 5e-59 6NBK-A nrPDB 221 3e-58 2EF5-A nrPDB 204 5e-53 3SL1-A nrPDB 140 8e-34 3NIP-A nrPDB 87 8e-18 1GQ7-A nrPDB 84 7e-17 4DZ4-A nrPDB 82 2e-16 4G3H-A nrPDB 79 4e-15 3NIO-A nrPDB 75 3e-14 3PZL-A nrPDB 73 2e-13 1WOG-A nrPDB 67 9e-12 4RHL-A nrPDB 63 2e-10 3LHL-A nrPDB 60 9e-10 3M1R-A nrPDB 57 1e-08 1XFK-A nrPDB 39 0.002 6N2B-A nrPDB 31 0.57 4V4O-A nrPDB 31 0.64 4Z25-A nrPDB 31 0.87 1MQS-A nrPDB 30 1.0 2VWH-A nrPDB 30 1.9 4R3U-A nrPDB 30 2.0 6AX8-A nrPDB 29 2.6 1SJP-A nrPDB 29 2.9 5NHE-A nrPDB 29 3.2 1W78-A nrPDB 28 3.7 4CVH-A nrPDB 28 4.7 3KST-A nrPDB 28 4.7 3S2F-A nrPDB 28 6.6 1WOU-A nrPDB 28 7.8 3HP7-A nrPDB 27 10.0 >3LP4-A nrPDB Length = 322 Score = 651 bits (1680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/322 (100%), Positives = 322/322 (100%) Query: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN Sbjct: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 Query: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV Sbjct: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 Query: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF Sbjct: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 Query: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT Sbjct: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 Query: 301 LACFGLAREGNHKPIDYLNPPK 322 LACFGLAREGNHKPIDYLNPPK Sbjct: 301 LACFGLAREGNHKPIDYLNPPK 322 >5RLA-A nrPDB Length = 323 Score = 574 bits (1480), Expect = e-164, Method: Compositional matrix adjust. Identities = 280/323 (86%), Positives = 301/323 (93%), Gaps = 1/323 (0%) Query: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 MS+K + I IIGAPFSKGQPRGGVE+GP LRKAGL+EKLKE E +V+D+GDL F D+PN Sbjct: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 Query: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 DSPFQIVKNPRSVGKA+EQLA VAE +KNG IS+VLGGD+S+AIGSISGHARVHPDL V Sbjct: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDNSMAIGSISGHARVHPDLCV 120 Query: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTT+SGNLHGQPV+FLLKELKGK PDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 DVDPGEHYI+KTLGIKYFSMTEVD+LGIGKVMEET SYLLGRKKRPIHLSFDVDGLDP F Sbjct: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 Query: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 TPATGTPVVGGL+YREGLYITEEIYKTGLLSGLDIMEVNP+LGKTPEEVTRTVNTAVA+T Sbjct: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 Query: 301 LACFGLAREGNHKP-IDYLNPPK 322 L+CFG REGNHKP DYL PPK Sbjct: 301 LSCFGTKREGNHKPETDYLKPPK 323 >1PQ3-A nrPDB Length = 306 Score = 400 bits (1029), Expect = e-112, Method: Compositional matrix adjust. Identities = 186/306 (60%), Positives = 233/306 (76%), Gaps = 1/306 (0%) Query: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQ 65 ++ +IGAPFS+GQ R GVE GP +R+AGL+++L C +KD+GDL F +P D + Sbjct: 1 HSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYN 60 Query: 66 -IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVD 124 ++ NPRSVG A+++LA V+ +G + LGGDHSLAIG+ISGHAR PDL V+WVD Sbjct: 61 NLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVD 120 Query: 125 AHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDP 184 AH DINTPLTT+SGNLHGQPVSFLL+EL+ K+P +PGFSW+ PCIS+ IVYIGLRDVDP Sbjct: 121 AHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDP 180 Query: 185 GEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPAT 244 EH+ILK I+YFSM ++DRLGI KVME T L+G+++RPIHLSFD+D DP+ PAT Sbjct: 181 PEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPAT 240 Query: 245 GTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACF 304 GTPVVGGLTYREG+YI EEI+ TGLLS LD++EVNP L + EE T N AV + + F Sbjct: 241 GTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSF 300 Query: 305 GLAREG 310 G REG Sbjct: 301 GQTREG 306 >5YNL-A nrPDB Length = 362 Score = 277 bits (708), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 150/307 (48%), Positives = 194/307 (63%), Gaps = 5/307 (1%) Query: 3 AKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYG-DLPFADIPND 61 A RT GI+G PFS GQP+ GV GP L ++GLL ++ V G D I +D Sbjct: 53 ATPRTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSD 112 Query: 62 SP---FQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDL 118 +P +K PR V + ++ +A +V G++++ LGGDHSLA+G++SG + +P+ Sbjct: 113 TPDPDIGRLKQPRLVSRVTKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKAYPEA 172 Query: 119 GVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIG 178 +IWVDAH DINTP TT SG LHG PVSFLL ++P FSW+ PC+ + IVYIG Sbjct: 173 CLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGTSSEEIPEFSWIKPCLKPERIVYIG 232 Query: 179 LRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDP 238 LRD+D GE ILK IK FSM VD+ GIGKV+E L ++ + RPIHLSFDVD LDP Sbjct: 233 LRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVNPDRTRPIHLSFDVDALDP 292 Query: 239 SFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVA 298 S P+TGT V GGLT+REG YI E I +T LL LDIME+NPSLG V +TV+ + Sbjct: 293 SVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGAL-ASVAQTVDVGRS 351 Query: 299 ITLACFG 305 + G Sbjct: 352 LVRCALG 358 >4Q3T-A nrPDB Length = 385 Score = 256 bits (654), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 138/327 (42%), Positives = 201/327 (61%), Gaps = 16/327 (4%) Query: 7 TIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDL-PFADIPNDSPFQ 65 + +G P ++GQP+ G +GP ++RK+ + + E + D GD+ P + P + Sbjct: 44 SANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQR 103 Query: 66 I-VKNPRSVGKASEQLAGKVAEVKKNGRIS------------LVLGGDHSLAIGSISGHA 112 +K RS + ++A +V E+ K +++GGDHS+A G+I GHA Sbjct: 104 FGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSKSTPLVIVGGDHSMATGTILGHA 163 Query: 113 RVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAK 172 PDL V+W+DAH DINTPL + SGN+HG P+SFL+KEL+ +IP + F + PC++A Sbjct: 164 EAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNAS 223 Query: 173 DIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFD 232 +I YIGLRD+D E + ++ GI YF+M +VDR+GI V++E L + R ++ IHLSFD Sbjct: 224 NIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFD 283 Query: 233 VDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRT 292 +D LDP P+TGT V GGLT REGL I EE+ TG LS +++ E+NP LG + E+V +T Sbjct: 284 IDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLG-SQEDVLKT 342 Query: 293 VNTAVAITLACFGLAREGNHKPIDYLN 319 ++AV I AC G R G H P N Sbjct: 343 QSSAVHILRACLGHCRSG-HLPFKVRN 368 >1CEV-A nrPDB Length = 299 Score = 237 bits (605), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 129/300 (43%), Positives = 192/300 (64%), Gaps = 10/300 (3%) Query: 8 IGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPF--ADIPNDSPFQ 65 I IIG P GQ R GV+ GP+ +R AG++E+L+ D++D GD+P A+ ++ Sbjct: 4 ISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDS 63 Query: 66 IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA 125 ++N ++V +A+E+LA V +V + GR LVLGGDHS+AIG+++G A+ + LGVIW DA Sbjct: 64 RLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDA 123 Query: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185 H D+NT T+ SGN+HG P++ L + + G+S P I + +V IG+R +D G Sbjct: 124 HGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYS---PKIKPEHVVLIGVRSLDEG 180 Query: 186 EHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATG 245 E ++ GIK ++M EVDRLG+ +VMEET++YL R +HLS D+DGLDPS P G Sbjct: 181 EKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKERTD-GVHLSLDLDGLDPSDAPGVG 239 Query: 246 TPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFG 305 TPV+GGLTYRE E + + +++ + +EVNP L +E +T + AVA+ + FG Sbjct: 240 TPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPIL----DERNKTASVAVALMGSLFG 295 >4ITY-A nrPDB Length = 330 Score = 235 bits (599), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 132/307 (42%), Positives = 178/307 (57%), Gaps = 8/307 (2%) Query: 5 SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDY----GDLPFADIPN 60 ++ + I+ APFS GQP GVE GP L K GL + +++ D + G + A + Sbjct: 13 AKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKAS 72 Query: 61 DSPFQI--VKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDL 118 D+ +I VK PR + +E++ V V + GR L +GGDHS+A+G+++G VHPD Sbjct: 73 DNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDA 132 Query: 119 GVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIG 178 GVIWVDAH DINT T SGNLHG P+S LL + IP+ FSWV + I YIG Sbjct: 133 GVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPEC--FSWVPQVLKPNKIAYIG 190 Query: 179 LRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDP 238 LR VD E IL L I FSM VDR GI KV+ + + + P+ +S+DVD +DP Sbjct: 191 LRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDP 250 Query: 239 SFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVA 298 + PATGTPV GGL++RE L++ E I + G L LD++E NP L T V T++ A Sbjct: 251 LYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISVGCA 310 Query: 299 ITLACFG 305 I G Sbjct: 311 IARCMMG 317 >6DKT-A nrPDB Length = 296 Score = 224 bits (570), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 127/302 (42%), Positives = 185/302 (61%), Gaps = 14/302 (4%) Query: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPF--ADIPNDSP 63 +TI +IG P GQ R GV+ GP+ +R A L+E+L + V+D GD+P I ND Sbjct: 3 KTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTVEDLGDIPINREKIKNDEE 62 Query: 64 FQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWV 123 KN SV +E+LA KV +V + + LVLGGDHS+AIG+++G A+ + +LGVIW Sbjct: 63 L---KNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIGTLAGTAKHYDNLGVIWY 119 Query: 124 DAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVD 183 DAH D+NT T+ SGN+HG P++ L + ++ G++ P I +++V IG R +D Sbjct: 120 DAHGDLNTLETSPSGNIHGMPLAVSLGIGHESLVNLEGYA---PKIKPENVVIIGARSLD 176 Query: 184 PGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPA 243 GE +K G+K ++M E+DRLG+ KV+EETL YL +HLS D+DGLDP+ P Sbjct: 177 EGERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYL--SACDGVHLSLDLDGLDPNDAPG 234 Query: 244 TGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLAC 303 GTPVVGG++YRE E +Y G+++ + +EVNP L + +T TAV + + Sbjct: 235 VGTPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPIL----DHKNKTGKTAVELVESL 290 Query: 304 FG 305 G Sbjct: 291 LG 292 >6NBK-A nrPDB Length = 297 Score = 221 bits (563), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 122/300 (40%), Positives = 178/300 (59%), Gaps = 9/300 (3%) Query: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQ 65 + I +IG P GQ R GV+ GP+ +R AG++E+++E DVKD GD+ Sbjct: 3 KEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDENT 62 Query: 66 IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA 125 ++N V +LA KV + + GR LVLGGDHS+AIG+++G A+ + +LGVIW DA Sbjct: 63 KLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDA 122 Query: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185 H D+NT T+ SGN+HG ++ L + D+ G P + +++V IG R +D G Sbjct: 123 HGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYG---AYPKVKKENVVIIGARALDEG 179 Query: 186 EHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATG 245 E ++ GIK FSM E+DR+G+ VMEET++YL +HLS D+DGLDP P G Sbjct: 180 EKDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYL--SHTDGVHLSLDLDGLDPHDAPGVG 237 Query: 246 TPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFG 305 TPV+GGL+YRE E + + +++ + +EVN L +E RT TAVA+ + FG Sbjct: 238 TPVIGGLSYRESHLAMEMLAEADIITSAEFVEVNTIL----DERNRTATTAVALMGSLFG 293 >2EF5-A nrPDB Length = 290 Score = 204 bits (519), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 117/298 (39%), Positives = 172/298 (57%), Gaps = 14/298 (4%) Query: 8 IGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIV 67 + ++G P G R GV+ GP+ LR A LLE+L++ V+D GD+P + Sbjct: 3 VAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRG 62 Query: 68 KNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHT 127 +A+ + + G +VLGGDHSL++GS++G AR +GV+WVDAH Sbjct: 63 LAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGR-RVGVVWVDAHA 121 Query: 128 DINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEH 187 D NTP T+ SGN+HG P++ L ++ +V F V P KD+V +G+R +DPGE Sbjct: 122 DFNTPETSPSGNVHGMPLAVLSGLGHPRLTEV--FRAVDP----KDVVLVGVRSLDPGEK 175 Query: 188 YILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTP 247 +LK G++ ++M EVDRLG+ ++ EE L +L G P+H+S D D LDP+ P GTP Sbjct: 176 RLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGL---PLHVSLDADVLDPTLAPGVGTP 232 Query: 248 VVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFG 305 V GGLTYRE + E + ++G + LD++EVNP L +E RT V + L+ G Sbjct: 233 VPGGLTYREAHLLMEILAESGRVQSLDLVEVNPIL----DERNRTAEMLVGLALSLLG 286 >3SL1-A nrPDB Length = 413 Score = 140 bits (353), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 124/232 (53%), Gaps = 5/232 (2%) Query: 60 NDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLG 119 N+ + ++N + +G S+ L ++ + L +GGDH +A SI +++ +L Sbjct: 154 NNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLR 213 Query: 120 VIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAK--DIVYI 177 VIW+DAH DIN P T+ SGN HG ++ L K K VP F W K + I Sbjct: 214 VIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKK---VPYFEWSENLTYLKPENTAII 270 Query: 178 GLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLD 237 G+RD+D E ILK I Y+++ ++++ GI + L + PIH+S D+D +D Sbjct: 271 GIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVD 330 Query: 238 PSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEV 289 F P TGT GGL YRE + + + +T + +D++E NPSL + ++V Sbjct: 331 NVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKV 382 Score = 36.6 bits (83), Expect = 0.015, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 28/53 (52%) Query: 5 SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFAD 57 S+ + IIG+P + GQP GGV+ LRK GL + +D G++ D Sbjct: 23 SKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNGD 75 >3NIP-A nrPDB Length = 326 Score = 87.4 bits (215), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 75/276 (27%), Positives = 120/276 (43%), Gaps = 28/276 (10%) Query: 8 IGIIGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQI 66 +G+IG P+ G R G GP +R L + + Y + D+ D+P Sbjct: 37 VGLIGVPWDGGTTNRAGARHGPREVRNLSSLMRKVHHVSRIAPYDLVRVGDL-GDAPV-- 93 Query: 67 VKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAH 126 NP + + ++ G +V G + L +GGDH + + R P LG++ DAH Sbjct: 94 --NPIDLLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGRERP-LGMVHFDAH 150 Query: 127 TDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRD--VDP 184 +D N + HG P ++E + P + V IG+R P Sbjct: 151 SDTNDRYFGDNPYTHGTPFRRAIEE-----------GLLDPLRT----VQIGIRGSVYSP 195 Query: 185 GEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPAT 244 + + GI+ M E LG+ + E + P ++SFDVD LDP+F P T Sbjct: 196 DDDAFARECGIRVIHMEEFVELGVEATLAEARRVV---GAGPTYVSFDVDVLDPAFAPGT 252 Query: 245 GTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNP 280 GTP +GG+T + + + L+ G D++EV+P Sbjct: 253 GTPEIGGMTSLQAQQLVRGLRGLDLV-GADVVEVSP 287 >1GQ7-A nrPDB Length = 313 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 82/284 (28%), Positives = 129/284 (45%), Gaps = 48/284 (16%) Query: 10 IIGAPFSKGQP-RGGVEEGPTVLR-KAGLLEKLKEQE-------CDVKDYGDLPFADIPN 60 +IGAP+ G R G GP +R ++GL+ + + D GD+ N Sbjct: 34 VIGAPYDGGTSYRPGARFGPQAIRSESGLIHGVGIDRGPGTFDLINCVDAGDI------N 87 Query: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 +PF + ++ A L+G + K N L++GGDHSL + ++ A H L V Sbjct: 88 LTPFDMNI---AIDTAQSHLSGLL---KANAAF-LMIGGDHSLTVAALRAVAEQHGPLAV 140 Query: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 + +DAH+D N P HG P + E I +V IG+R Sbjct: 141 VHLDAHSDTN-PAFYGGRYHHGTPFRHGIDE---------------KLIDPAAMVQIGIR 184 Query: 181 DVDPGEHYI--LKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRK--KRPIHLSFDVDGL 236 +P + + G++ + E LG+G + L+ K +RP+++S D+D + Sbjct: 185 GHNPKPDSLDYARGHGVRVVTADEFGELGVGGTAD-----LIREKVGQRPVYVSVDIDVV 239 Query: 237 DPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNP 280 DP+F P TGTP GGL RE L + + + G D+MEV+P Sbjct: 240 DPAFAPGTGTPAPGGLLSREVLALLRCVGDLKPV-GFDVMEVSP 282 >4DZ4-A nrPDB Length = 324 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 85/295 (28%), Positives = 127/295 (43%), Gaps = 35/295 (11%) Query: 21 RGGVEEGPTVLRKAGL-LEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQ 79 R G GP+ +R A + L +L + DL D D F +P S+ A + Sbjct: 63 RSGARLGPSAVRAASVQLAELNPYPWGFDPFDDLAVIDY-GDCWFD-AHHPLSIKPAIVE 120 Query: 80 LAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPD-LGVIWVDAHTDINTPLTTTSG 138 A + ++ + R+ L LGGDH + + HA+ + L +I DAH D S Sbjct: 121 HARTI--LQSDARM-LTLGGDHYITYPLLIAHAQKYGKPLSLIHFDAHCDTWADDAPDSL 177 Query: 139 NLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYF 198 N HG + K +K + I K V +G+R + LGI Sbjct: 178 N-HG---TMFYKAVKDGL------------IDPKASVQVGIRTWND------DYLGINVL 215 Query: 199 SMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGL 258 V G +E S + GR P +L+FD+D LDP+F P TGTPV GGL+ + L Sbjct: 216 DAAWVHEHGARATLERIESIVGGR---PAYLTFDIDCLDPAFAPGTGTPVAGGLSSAQAL 272 Query: 259 YITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHK 313 I + L+ G D++EV P+ ++ E+T VA L C R+ + Sbjct: 273 AIVRGLGGVNLI-GADVVEVAPAYDQS--EITAIAAAHVACDLLCLWRQRKAGAR 324 >4G3H-A nrPDB Length = 330 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 60/247 (24%), Positives = 113/247 (45%), Gaps = 22/247 (8%) Query: 76 ASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPD--LGVIWVDAHTDINTPL 133 E L + EV + L+L +H+ G VH D +G++++DAH DI+T Sbjct: 66 CKENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAY 125 Query: 134 TTTSGNLHGQPVSFLLKELK---GKIPDVPGFSWVTPC----------ISAKDIVYIGLR 180 + S ++HG P+ +L ++ ++ + +W C I K +VY G+R Sbjct: 126 DSDSKHIHGMPLGMVLNRVRSGFNRMSESEEKAWQKLCSLGLEKGGLEIDPKCLVYFGVR 185 Query: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 + E +++ L I FS+ + R + +V+++T L + I+LS D+D +D Sbjct: 186 STEQSERDVIRELQIPLFSVDAI-RENMQEVVQKTKESL--KAVDIIYLSLDLDIMDGKL 242 Query: 241 TPATGTPVVGGLTYREGLYITEEIYKT--GLLSGLDIMEVNP--SLGKTPEEVTRTVNTA 296 +TG GL++ E + + ++ L +++ E NP S+ EE + + Sbjct: 243 FTSTGVRENNGLSFDELKQLLGLLLESFKDRLKAVEVTEYNPTVSIKHNNEEEKQVLEIL 302 Query: 297 VAITLAC 303 I +C Sbjct: 303 DLIINSC 309 >3NIO-A nrPDB Length = 319 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 67/277 (24%), Positives = 122/277 (44%), Gaps = 32/277 (11%) Query: 9 GIIGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDS--PFQ 65 +G P G R G GP +R ++ + + L ADI + + F Sbjct: 41 AFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIGDVAINTFN 100 Query: 66 IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA 125 +++ R + + +++ G +G + L LGGDH++ + + + H +G++ VDA Sbjct: 101 LLEAVRIIEQEYDRILG-------HGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDA 153 Query: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRD--VD 183 H D+N ++ G+ ++ + D+ + +V IGLR Sbjct: 154 HADVND-------HMFGEKIAHGTTFRRAVEEDL---------LDCDRVVQIGLRAQGYT 197 Query: 184 PGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPA 243 + + G + E + +M E + G P++LSFD+DG+DP++ P Sbjct: 198 AEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGG---PVYLSFDIDGIDPAWAPG 254 Query: 244 TGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNP 280 TGTP +GGLT + + I L+ G D++EV+P Sbjct: 255 TGTPEIGGLTTIQAMEIIRGCQGLDLI-GCDLVEVSP 290 >3PZL-A nrPDB Length = 313 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 30/198 (15%) Query: 84 VAEVKKNGRISLVLGGDHSLAIGSISGHARVHP-DLGVIWVDAHTDINTPLTTTSGNLHG 142 V+ V +G+I ++LGG+HS+ +G++ R P D+ ++ VDAH+D + GN + Sbjct: 107 VSAVMSDGKIPIMLGGEHSITVGAV----RALPKDVDLVIVDAHSDFRSSYM---GNKYN 159 Query: 143 QPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTE 202 + + D+ G +T IG+R V E + + S + Sbjct: 160 HAC------VTRRALDLLGEGRITS---------IGIRSVSREEFEDPDFRKVSFISSFD 204 Query: 203 VDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITE 262 V + GI K +EE + RK R +++S D+DG+DP++ PA GTP GL + + E Sbjct: 205 VKKNGIDKYIEE-----VDRKSRRVYISVDMDGIDPAYAPAVGTPEPFGLADTDVRRLIE 259 Query: 263 EIYKTGLLSGLDIMEVNP 280 + + G DI+E +P Sbjct: 260 RLSYKAV--GFDIVEFSP 275 >1WOG-A nrPDB Length = 305 Score = 67.4 bits (163), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 77/292 (26%), Positives = 120/292 (41%), Gaps = 54/292 (18%) Query: 8 IGIIGAPFSKGQP-RGGVEEGPTVLRKA---------GLLEKLKEQECDVKDYGDLPFAD 57 + +G PF R G P LR+A GL K + Q D GD+ Sbjct: 31 VAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGDV---I 87 Query: 58 IPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPD 117 +P+ P Q+ + + +A+ Q+ G+ R+ + LGGDHS++ + A V PD Sbjct: 88 LPSLEP-QLAHD--RITEAARQVRGRC-------RVPVFLGGDHSVSYPLLRAFADV-PD 136 Query: 118 LGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYI 177 L V+ +DAH D T + + P + L + I + Sbjct: 137 LHVVQLDAHLDFTDTRNDTKWS-NSSPFRRACEALPNLV----------------HITTV 179 Query: 178 GLRDV--DPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKR--PIHLSFDV 233 GLR + DP + G M +V L+ +L + R ++ S DV Sbjct: 180 GLRGLRFDPEAVAAARARGHTIIPMDDV---------TADLAGVLAQLPRGQNVYFSVDV 230 Query: 234 DGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKT 285 DG DP+ P T +P GLTY +G+ I + GLD++E+ P+L T Sbjct: 231 DGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPT 282 >4RHL-A nrPDB Length = 351 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 73/295 (24%), Positives = 121/295 (41%), Gaps = 68/295 (23%) Query: 32 RKAGLLEKLKEQECDVKDYGDLPFADI------PNDSPFQIVKNPRSVGKASEQLAG--- 82 R+A LL+ + D Y +L D P F V N G+ ++ AG Sbjct: 57 RRAPLLDFFLQSPRDCDHYAELTIHDKGPIECPPETVMFMPVLN---CGQMLDEAAGTET 113 Query: 83 ------------KVAEVKKNGRISLVLGGDHSLAIGSISGHARVHP--DLGVIWVDAHTD 128 E+ + G + + +GGD S + + + R+ P D+ ++ DAH Sbjct: 114 PTSDEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFPSDDIVIVHFDAHPS 173 Query: 129 INTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHY 188 ++ P + P+ LL KG + K +V +G R V + Sbjct: 174 VSDPRS---------PLRVLLD--KGLL---------------KGVVSVGNRQVSSEDRK 207 Query: 189 ILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPV 248 + K + Y M + G+ + + R P+ +S D D LDP+F PA +PV Sbjct: 208 VRKLHKMFYMDMHAIYSKGLFCIRDI-------RNDYPVFISIDADVLDPAFAPAVDSPV 260 Query: 249 VGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVN---TAVAIT 300 GGL+ R+ L+I I ++ G+D+ NP L +V R N TA+A++ Sbjct: 261 AGGLSTRDLLHIMNGIRGPKVV-GIDVYGYNPDL-----DVYRKDNVGLTAIALS 309 >3LHL-A nrPDB Length = 287 Score = 60.5 bits (145), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 64/265 (24%), Positives = 111/265 (41%), Gaps = 51/265 (19%) Query: 40 LKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGG 99 L ++ ++ DYGDL +I S Q++K ++ + ++ ++ ++ ++GG Sbjct: 50 LDLEDYNICDYGDL---EISVGSTEQVLK----------EIYQETYKIVRDSKVPFMIGG 96 Query: 100 DHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDV 159 +H + + + + D+ VI DAHTD+ S N H + +I D+ Sbjct: 97 EHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNN-SKNSHATVIK--------RIWDI 147 Query: 160 PGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYL 219 G I G+R E Y + +D E ++ L Sbjct: 148 VG---------DNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGID------TFENIVNML 192 Query: 220 LGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGL-LSGLDIMEV 278 G+ I+L+ D+D LD S P TGTP GG+ YRE I + I + + + G DI+E+ Sbjct: 193 NGKN---IYLTIDLDVLDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVEL 249 Query: 279 NPSLGKTPEEVTRTVNTAVAITLAC 303 +P T V+ +AC Sbjct: 250 SPDYD----------TTGVSTVIAC 264 >3M1R-A nrPDB Length = 322 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 70/285 (24%), Positives = 118/285 (41%), Gaps = 41/285 (14%) Query: 9 GIIGAPFSKGQ-PRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPND------ 61 +IG P SK G P +R+A LK + G+ +++ D Sbjct: 41 ALIGVPLSKSSISHSGASFAPGTIRQA-----LKHSSAYSAELGEHVVSELLYDLGDIDI 95 Query: 62 SPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVI 121 IVK+ + + L + + L+LGGD+S++ +I A+ VI Sbjct: 96 HVTDIVKSHHHIFQTMHALLSDHPD-----WVPLILGGDNSISYSTIKAIAQTKGTTAVI 150 Query: 122 WVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRD 181 DAH D+ T G +G P LL E I + ++ +G+R+ Sbjct: 151 QFDAHHDVRN--TEDGGPTNGTPFRRLLDE---------------EIIEGQHLIQLGIRE 193 Query: 182 VDPGEHY--ILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPS 239 + Y K + +M + G+ ++E L ++ K I +S D+D LD S Sbjct: 194 FSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILP-VVQDKTDFIFISVDMDVLDQS 252 Query: 240 FTPATGTPVVG--GLTYREGLYITEEIYKTGLLSGLDIMEVNPSL 282 P G P +G GL E L + I + ++G++I+EV+P+L Sbjct: 253 HAP--GCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTL 295 >1XFK-A nrPDB Length = 336 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/238 (21%), Positives = 87/238 (36%), Gaps = 36/238 (15%) Query: 63 PFQIVKNPRSVGKASEQLAGKVAEVKKNG---RISLVLGGDHSLAIGSISGHAR------ 113 P + N R G EQ + A+V + ++VLGG H +A + G A+ Sbjct: 86 PIYDLGNIRCEGDELEQAQQECAQVIQQALPHARAIVLGGGHEIAWATFQGLAQHFLATG 145 Query: 114 -VHPDLGVIWVDAHTDINT------PLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVT 166 P +G+I DAH D+ T P+ +SG Q F ++ G+ + Sbjct: 146 VKQPRIGIINFDAHFDLRTFESELAPVRPSSGTPFNQIHHFCQQQ---------GWDFHY 196 Query: 167 PCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRP 226 C+ + P LG+ Y L + + + ++ Sbjct: 197 ACLG------VSRASNTPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFI--DDCDY 248 Query: 227 IHLSFDVDGLDPSFTPATGTPVVGGLTYREGL--YITEEIYKTGLLSGLDIMEVNPSL 282 ++L+ D+D + P P G++ E L Y ++ L DI E NPS Sbjct: 249 LYLTIDLDVFPAASAPGVSAPAARGVSL-EALAPYFDRILHYKNKLMIADIAEYNPSF 305 >6N2B-A nrPDB Length = 577 Score = 31.2 bits (69), Expect = 0.57, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 2/89 (2%) Query: 22 GGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLA 81 GG+E KA E + E VK+YG+ I + N R+ K+ L Sbjct: 299 GGMELNGYGYYKAN--EIYSDGEVQVKNYGNFEIGSIGIVKKLTVTDNGRTTIKSGATLY 356 Query: 82 GKVAEVKKNGRISLVLGGDHSLAIGSISG 110 EV+ NGR+ + G SISG Sbjct: 357 CDQLEVRNNGRVFIEAGATLVTRAISISG 385 >4V4O-A nrPDB Length = 543 Score = 31.2 bits (69), Expect = 0.64, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 30/59 (50%) Query: 148 LLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRL 206 LLKE+ K DV G T + A+ IV GL++V G + + GI+ V+++ Sbjct: 72 LLKEVASKTNDVAGDGTTTATVLAQAIVREGLKNVAAGANPLALKRGIEKAVEAAVEKI 130 >4Z25-A nrPDB Length = 652 Score = 30.8 bits (68), Expect = 0.87, Method: Compositional matrix adjust. Identities = 50/220 (22%), Positives = 86/220 (39%), Gaps = 56/220 (25%) Query: 142 GQPVSFLLKELKGKIPDVPGFSWVTP--------------CISAKDIVYIGLRDVDPGEH 187 G+PV FLL + G +P+V TP + A Y+G+ + G + Sbjct: 171 GEPVDFLLNKATGNVPNVEK---TTPDAVPLNLNDYEGVNSVVAFSSFYMGVNQLSDG-N 226 Query: 188 YILKTLGIKYFSMTEVDR--LGIGK------VMEETLSYLLGRKKRPIHLSF-DVDGL-- 236 YI K G Y + VD GIGK V + + ++ + R + +++ D +G+ Sbjct: 227 YIRKYAGNTYLNRNYVDENGRGIGKFSGLRVVSDAVVDRIIFKGNRAVGVNYIDREGIMH 286 Query: 237 ----------------DPSFTPATGTPVVGGLTYREGLYITEEIYK-----TGLLSGLDI 275 P+ +G +G TY + + +Y TGL + Sbjct: 287 YVKVNKEVVVTSGAFYTPTILQRSG---IGDFTYLSSIGVKNLVYNNPLVGTGLKNHYSP 343 Query: 276 MEVNPSLGKTPEEVTRTVNTAVA--ITLACFGLAREGNHK 313 + + G+ P EV+R ++ A + GLA G H+ Sbjct: 344 VTITRVHGE-PSEVSRFLSNMAANPTNMGFKGLAELGFHR 382 >1MQS-A nrPDB Length = 671 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 6/76 (7%) Query: 120 VIWVDAHTDINTPLTTTS----GNL--HGQPVSFLLKELKGKIPDVPGFSWVTPCISAKD 173 +IW DI + T +S +L G V L+K+ + +PDVP +V+P D Sbjct: 56 IIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENID 115 Query: 174 IVYIGLRDVDPGEHYI 189 I+ L+ E YI Sbjct: 116 IIVNDLKSDKYSEFYI 131 >2VWH-A nrPDB Length = 357 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 8/70 (11%) Query: 181 DVDPGEHYILK--TLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDP 238 D DP ++L +LG+ +M +VD G + Y LGR+ RP ++ LD Sbjct: 170 DWDPSSAFVLGNGSLGLLTLAMLKVDDKGYENL------YCLGRRDRPDPTIDIIEELDA 223 Query: 239 SFTPATGTPV 248 ++ + TPV Sbjct: 224 TYVDSRQTPV 233 >4R3U-A nrPDB Length = 584 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 42/195 (21%), Positives = 77/195 (39%), Gaps = 24/195 (12%) Query: 119 GVIWVDAHTDINTPLTTTSGNLHGQPVSFLLK---ELKGKIPDVPGFSWVTPCISAKDIV 175 G+ W++ I + L + + V LK E K + + F V +A DI Sbjct: 11 GMTWLEPQ--IKSQLQSERKDWEANEVGAFLKKAPERKEQFHTIGDFP-VQRTYTAADIA 67 Query: 176 YIGLRDVD-PGEHYILK-----TLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHL 229 L D+ PG + + + ++M ++ G G+ + YL+ + + I Sbjct: 68 DTPLEDIGLPGRYPFTRGPYPTMYRSRTWTMRQIAGFGTGEDTNKRFKYLIAQGQTGIST 127 Query: 230 SFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEV 289 FD+ L + P+ G REG+ I LL+ +D+ +++ S Sbjct: 128 DFDMPTL---MGYDSDHPMSDGEVGREGVAIDTLADMEALLADIDLEKISVSF------- 177 Query: 290 TRTVNTAVAITLACF 304 T+N + I LA + Sbjct: 178 --TINPSAWILLAMY 190 >6AX8-A nrPDB Length = 519 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 127 TDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPG 161 T INT L GNL + +S + K L G++P+ PG Sbjct: 345 TRINTDLANELGNLAQRSLSMVAKNLDGRVPN-PG 378 >1SJP-A nrPDB Length = 504 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 13/73 (17%) Query: 148 LLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLG 207 L+KE+ K DV G T + A+ +V GLR+V G + LG+K G Sbjct: 30 LVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGAN----PLGLKR---------G 76 Query: 208 IGKVMEETLSYLL 220 I K +E+ LL Sbjct: 77 IEKAVEKVTETLL 89 >5NHE-A nrPDB Length = 437 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 167 PCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYL 219 P D + I + VD G I++ LGI Y+ +VD + G +EE S L Sbjct: 69 PWNEGTDAIEIAKQKVDAG-FEIMQKLGIPYYCFHDVDLVSEGNSIEEYESNL 120 >1W78-A nrPDB Length = 422 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 7/47 (14%) Query: 58 IPNDSP---FQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDH 101 I ++SP F + NP A+E L G++ + KNGR+ V+G H Sbjct: 292 IVSESPRVIFDVAHNPH----AAEYLTGRMKALPKNGRVLAVIGMLH 334 >4CVH-A nrPDB Length = 411 Score = 28.1 bits (61), Expect = 4.7, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 245 GTPVVGGLTYREGLYITEEIYK----TGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 G+P + +TY+ LY E I K + +D E N +G EEV ++ V +T Sbjct: 217 GSPDLWKVTYKRDLYAAESIIKERISQEICVVMDTEEDNKHVGHLLEEVLKSELNHVKVT 276 Query: 301 LACFGLAREGNH 312 G A G H Sbjct: 277 SEALGHA--GRH 286 >3KST-A nrPDB Length = 306 Score = 28.1 bits (61), Expect = 4.7, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 3/85 (3%) Query: 1 MSAKSRTIG-IIGAPFSKGQPRGGVEEGPTVLRKAGLLEKL-KEQECDVKDYG-DLPFAD 57 MS K+ T+ I A S +G V EGP++L+K G+ + + K YG +D Sbjct: 164 MSIKTETLNQCIKAEVSWELLQGKVAEGPSLLKKNGVYYLIYSANHYENKGYGVGYATSD 223 Query: 58 IPNDSPFQIVKNPRSVGKASEQLAG 82 P + KNP G A+ L G Sbjct: 224 TPMGPWVKYSKNPLLQGDAATGLVG 248 >3S2F-A nrPDB Length = 340 Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 154 GKIPDVPGFSWVTPCISAKDIVYIGLR--DVDPGEHYILKTLG 194 G +PD GF + P + A VY GL+ D PG+ ++ +G Sbjct: 134 GLLPDKVGFVEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIG 176 >1WOU-A nrPDB Length = 123 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 20/39 (51%) Query: 158 DVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIK 196 D G SW C+ A+ +V GL+ + G +I +G K Sbjct: 36 DAGGKSWCPDCVQAEPVVREGLKHISEGCVFIYCQVGEK 74 >3HP7-A nrPDB Length = 291 Score = 27.3 bits (59), Expect = 10.0, Method: Compositional matrix adjust. Identities = 11/28 (39%), Positives = 19/28 (67%) Query: 252 LTYREGLYITEEIYKTGLLSGLDIMEVN 279 L Y++GL+ T E K G+++GL + +N Sbjct: 12 LAYKQGLFETREQAKRGVMAGLVVNVIN 39 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3LP4-A nrPDB 445 e-126 5RLA-A nrPDB 432 e-121 1PQ3-A nrPDB 379 e-106 1CEV-A nrPDB 349 1e-96 6NBK-A nrPDB 345 2e-95 5YNL-A nrPDB 339 1e-93 6DKT-A nrPDB 337 5e-93 4Q3T-A nrPDB 335 1e-92 4ITY-A nrPDB 333 7e-92 2EF5-A nrPDB 301 2e-82 3SL1-A nrPDB 255 2e-68 3NIO-A nrPDB 238 3e-63 3NIP-A nrPDB 235 2e-62 4DZ4-A nrPDB 235 2e-62 3LHL-A nrPDB 210 1e-54 1GQ7-A nrPDB 208 2e-54 4G3H-A nrPDB 208 3e-54 3M1R-A nrPDB 207 6e-54 3PZL-A nrPDB 183 7e-47 1WOG-A nrPDB 182 1e-46 4RHL-A nrPDB 173 7e-44 Sequences not found previously or not previously below threshold: 1XFK-A nrPDB 99 3e-21 3A1K-A nrPDB 33 0.14 3TAI-A nrPDB 31 0.82 1GKH-A nrPDB 29 2.5 3VUE-A nrPDB 29 4.1 5M7N-A nrPDB 28 4.6 4D6Y-A nrPDB 28 5.6 >3LP4-A nrPDB Length = 322 Score = 445 bits (1145), Expect = e-126, Method: Composition-based stats. Identities = 322/322 (100%), Positives = 322/322 (100%) Query: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN Sbjct: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 Query: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV Sbjct: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 Query: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF Sbjct: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 Query: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT Sbjct: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 Query: 301 LACFGLAREGNHKPIDYLNPPK 322 LACFGLAREGNHKPIDYLNPPK Sbjct: 301 LACFGLAREGNHKPIDYLNPPK 322 >5RLA-A nrPDB Length = 323 Score = 432 bits (1111), Expect = e-121, Method: Composition-based stats. Identities = 280/323 (86%), Positives = 301/323 (93%), Gaps = 1/323 (0%) Query: 1 MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN 60 MS+K + I IIGAPFSKGQPRGGVE+GP LRKAGL+EKLKE E +V+D+GDL F D+PN Sbjct: 1 MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPN 60 Query: 61 DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV 120 DSPFQIVKNPRSVGKA+EQLA VAE +KNG IS+VLGGD+S+AIGSISGHARVHPDL V Sbjct: 61 DSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDNSMAIGSISGHARVHPDLCV 120 Query: 121 IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR 180 IWVDAHTDINTPLTT+SGNLHGQPV+FLLKELKGK PDVPGFSWVTPCISAKDIVYIGLR Sbjct: 121 IWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLR 180 Query: 181 DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF 240 DVDPGEHYI+KTLGIKYFSMTEVD+LGIGKVMEET SYLLGRKKRPIHLSFDVDGLDP F Sbjct: 181 DVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVF 240 Query: 241 TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 TPATGTPVVGGL+YREGLYITEEIYKTGLLSGLDIMEVNP+LGKTPEEVTRTVNTAVA+T Sbjct: 241 TPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALT 300 Query: 301 LACFGLAREGNHKP-IDYLNPPK 322 L+CFG REGNHKP DYL PPK Sbjct: 301 LSCFGTKREGNHKPETDYLKPPK 323 >1PQ3-A nrPDB Length = 306 Score = 379 bits (973), Expect = e-106, Method: Composition-based stats. Identities = 186/306 (60%), Positives = 233/306 (76%), Gaps = 1/306 (0%) Query: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQ 65 ++ +IGAPFS+GQ R GVE GP +R+AGL+++L C +KD+GDL F +P D + Sbjct: 1 HSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYN 60 Query: 66 -IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVD 124 ++ NPRSVG A+++LA V+ +G + LGGDHSLAIG+ISGHAR PDL V+WVD Sbjct: 61 NLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVD 120 Query: 125 AHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDP 184 AH DINTPLTT+SGNLHGQPVSFLL+EL+ K+P +PGFSW+ PCIS+ IVYIGLRDVDP Sbjct: 121 AHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDP 180 Query: 185 GEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPAT 244 EH+ILK I+YFSM ++DRLGI KVME T L+G+++RPIHLSFD+D DP+ PAT Sbjct: 181 PEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPAT 240 Query: 245 GTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACF 304 GTPVVGGLTYREG+YI EEI+ TGLLS LD++EVNP L + EE T N AV + + F Sbjct: 241 GTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSF 300 Query: 305 GLAREG 310 G REG Sbjct: 301 GQTREG 306 >1CEV-A nrPDB Length = 299 Score = 349 bits (894), Expect = 1e-96, Method: Composition-based stats. Identities = 129/304 (42%), Positives = 192/304 (63%), Gaps = 10/304 (3%) Query: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPF--ADIPNDSP 63 + I IIG P GQ R GV+ GP+ +R AG++E+L+ D++D GD+P A+ ++ Sbjct: 2 KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQG 61 Query: 64 FQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWV 123 ++N ++V +A+E+LA V +V + GR LVLGGDHS+AIG+++G A+ + LGVIW Sbjct: 62 DSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWY 121 Query: 124 DAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVD 183 DAH D+NT T+ SGN+HG P++ L + + G+S P I + +V IG+R +D Sbjct: 122 DAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQIGGYS---PKIKPEHVVLIGVRSLD 178 Query: 184 PGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPA 243 GE ++ GIK ++M EVDRLG+ +VMEET++YL R +HLS D+DGLDPS P Sbjct: 179 EGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKER-TDGVHLSLDLDGLDPSDAPG 237 Query: 244 TGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLAC 303 GTPV+GGLTYRE E + + +++ + +EVNP L E +T + AVA+ + Sbjct: 238 VGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILD----ERNKTASVAVALMGSL 293 Query: 304 FGLA 307 FG Sbjct: 294 FGEK 297 >6NBK-A nrPDB Length = 297 Score = 345 bits (884), Expect = 2e-95, Method: Composition-based stats. Identities = 122/304 (40%), Positives = 178/304 (58%), Gaps = 9/304 (2%) Query: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQ 65 + I +IG P GQ R GV+ GP+ +R AG++E+++E DVKD GD+ Sbjct: 3 KEISVIGVPMDLGQMRRGVDMGPSAIRYAGVIERIEEIGYDVKDMGDICIEREKEIDENT 62 Query: 66 IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA 125 ++N V +LA KV + + GR LVLGGDHS+AIG+++G A+ + +LGVIW DA Sbjct: 63 KLRNLTQVATVCNELASKVDHIIEEGRFPLVLGGDHSIAIGTLAGVAKHYKNLGVIWYDA 122 Query: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPG 185 H D+NT T+ SGN+HG ++ L + D+ G P + +++V IG R +D G Sbjct: 123 HGDLNTEETSPSGNIHGMSLAASLGYGHSSLVDLYG---AYPKVKKENVVIIGARALDEG 179 Query: 186 EHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATG 245 E ++ GIK FSM E+DR+G+ VMEET++YL +HLS D+DGLDP P G Sbjct: 180 EKDFIRNEGIKVFSMHEIDRMGMTAVMEETIAYL--SHTDGVHLSLDLDGLDPHDAPGVG 237 Query: 246 TPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFG 305 TPV+GGL+YRE E + + +++ + +EVN L E RT TAVA+ + FG Sbjct: 238 TPVIGGLSYRESHLAMEMLAEADIITSAEFVEVNTILD----ERNRTATTAVALMGSLFG 293 Query: 306 LARE 309 + Sbjct: 294 EKLK 297 >5YNL-A nrPDB Length = 362 Score = 339 bits (869), Expect = 1e-93, Method: Composition-based stats. Identities = 150/309 (48%), Positives = 194/309 (62%), Gaps = 5/309 (1%) Query: 3 AKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYG-DLPFADIPND 61 A RT GI+G PFS GQP+ GV GP L ++GLL ++ V G D I +D Sbjct: 53 ATPRTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSD 112 Query: 62 SPF---QIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDL 118 +P +K PR V + ++ +A +V G++++ LGGDHSLA+G++SG + +P+ Sbjct: 113 TPDPDIGRLKQPRLVSRVTKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKAYPEA 172 Query: 119 GVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIG 178 +IWVDAH DINTP TT SG LHG PVSFLL ++P FSW+ PC+ + IVYIG Sbjct: 173 CLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGTSSEEIPEFSWIKPCLKPERIVYIG 232 Query: 179 LRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDP 238 LRD+D GE ILK IK FSM VD+ GIGKV+E L ++ + RPIHLSFDVD LDP Sbjct: 233 LRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVNPDRTRPIHLSFDVDALDP 292 Query: 239 SFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVA 298 S P+TGT V GGLT+REG YI E I +T LL LDIME+NPSLG V +TV+ + Sbjct: 293 SVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGAL-ASVAQTVDVGRS 351 Query: 299 ITLACFGLA 307 + G Sbjct: 352 LVRCALGET 360 >6DKT-A nrPDB Length = 296 Score = 337 bits (863), Expect = 5e-93, Method: Composition-based stats. Identities = 127/304 (41%), Positives = 185/304 (60%), Gaps = 14/304 (4%) Query: 6 RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPF--ADIPNDSP 63 +TI +IG P GQ R GV+ GP+ +R A L+E+L + V+D GD+P I ND Sbjct: 3 KTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTVEDLGDIPINREKIKNDEE 62 Query: 64 FQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWV 123 +KN SV +E+LA KV +V + + LVLGGDHS+AIG+++G A+ + +LGVIW Sbjct: 63 ---LKNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIGTLAGTAKHYDNLGVIWY 119 Query: 124 DAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVD 183 DAH D+NT T+ SGN+HG P++ L + ++ G++ P I +++V IG R +D Sbjct: 120 DAHGDLNTLETSPSGNIHGMPLAVSLGIGHESLVNLEGYA---PKIKPENVVIIGARSLD 176 Query: 184 PGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPA 243 GE +K G+K ++M E+DRLG+ KV+EETL YL +HLS D+DGLDP+ P Sbjct: 177 EGERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYL--SACDGVHLSLDLDGLDPNDAPG 234 Query: 244 TGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLAC 303 GTPVVGG++YRE E +Y G+++ + +EVNP L +T TAV + + Sbjct: 235 VGTPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPILD----HKNKTGKTAVELVESL 290 Query: 304 FGLA 307 G Sbjct: 291 LGKK 294 >4Q3T-A nrPDB Length = 385 Score = 335 bits (859), Expect = 1e-92, Method: Composition-based stats. Identities = 138/327 (42%), Positives = 201/327 (61%), Gaps = 16/327 (4%) Query: 7 TIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDL-PFADIPNDSPFQ 65 + +G P ++GQP+ G +GP ++RK+ + + E + D GD+ P + P + Sbjct: 44 SANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQR 103 Query: 66 I-VKNPRSVGKASEQLAGKVAEVKKNGRIS------------LVLGGDHSLAIGSISGHA 112 +K RS + ++A +V E+ K +++GGDHS+A G+I GHA Sbjct: 104 FGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSKSTPLVIVGGDHSMATGTILGHA 163 Query: 113 RVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAK 172 PDL V+W+DAH DINTPL + SGN+HG P+SFL+KEL+ +IP + F + PC++A Sbjct: 164 EAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNAS 223 Query: 173 DIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFD 232 +I YIGLRD+D E + ++ GI YF+M +VDR+GI V++E L + R ++ IHLSFD Sbjct: 224 NIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFD 283 Query: 233 VDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRT 292 +D LDP P+TGT V GGLT REGL I EE+ TG LS +++ E+NP LG + E+V +T Sbjct: 284 IDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLG-SQEDVLKT 342 Query: 293 VNTAVAITLACFGLAREGNHKPIDYLN 319 ++AV I AC G R G H P N Sbjct: 343 QSSAVHILRACLGHCRSG-HLPFKVRN 368 >4ITY-A nrPDB Length = 330 Score = 333 bits (853), Expect = 7e-92, Method: Composition-based stats. Identities = 132/309 (42%), Positives = 178/309 (57%), Gaps = 8/309 (2%) Query: 5 SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDY----GDLPFADIPN 60 ++ + I+ APFS GQP GVE GP L K GL + +++ D + G + A + Sbjct: 13 AKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKAS 72 Query: 61 DSPFQI--VKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDL 118 D+ +I VK PR + +E++ V V + GR L +GGDHS+A+G+++G VHPD Sbjct: 73 DNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDA 132 Query: 119 GVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIG 178 GVIWVDAH DINT T SGNLHG P+S LL + IP+ FSWV + I YIG Sbjct: 133 GVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPEC--FSWVPQVLKPNKIAYIG 190 Query: 179 LRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDP 238 LR VD E IL L I FSM VDR GI KV+ + + + P+ +S+DVD +DP Sbjct: 191 LRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDP 250 Query: 239 SFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVA 298 + PATGTPV GGL++RE L++ E I + G L LD++E NP L T V T++ A Sbjct: 251 LYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISVGCA 310 Query: 299 ITLACFGLA 307 I G Sbjct: 311 IARCMMGET 319 >2EF5-A nrPDB Length = 290 Score = 301 bits (771), Expect = 2e-82, Method: Composition-based stats. Identities = 114/299 (38%), Positives = 169/299 (56%), Gaps = 14/299 (4%) Query: 8 IGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIV 67 + ++G P G R GV+ GP+ LR A LLE+L++ V+D GD+P + Sbjct: 3 VAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRG 62 Query: 68 KNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHT 127 +A+ + + G +VLGGDHSL++GS++G AR +GV+WVDAH Sbjct: 63 LAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGR-RVGVVWVDAHA 121 Query: 128 DINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEH 187 D NTP T+ SGN+HG P++ L ++ +V + KD+V +G+R +DPGE Sbjct: 122 DFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFR------AVDPKDVVLVGVRSLDPGEK 175 Query: 188 YILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTP 247 +LK G++ ++M EVDRLG+ ++ EE L +L G P+H+S D D LDP+ P GTP Sbjct: 176 RLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGL---PLHVSLDADVLDPTLAPGVGTP 232 Query: 248 VVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGL 306 V GGLTYRE + E + ++G + LD++EVNP L E RT V + L+ G Sbjct: 233 VPGGLTYREAHLLMEILAESGRVQSLDLVEVNPILD----ERNRTAEMLVGLALSLLGK 287 >3SL1-A nrPDB Length = 413 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 77/235 (32%), Positives = 125/235 (53%), Gaps = 5/235 (2%) Query: 57 DIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHP 116 N+ + ++N + +G S+ L ++ + L +GGDH +A SI +++ Sbjct: 151 KYKNNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQ 210 Query: 117 DLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPC--ISAKDI 174 +L VIW+DAH DIN P T+ SGN HG ++ L K K VP F W + ++ Sbjct: 211 NLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKK---VPYFEWSENLTYLKPENT 267 Query: 175 VYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVD 234 IG+RD+D E ILK I Y+++ ++++ GI + L + PIH+S D+D Sbjct: 268 AIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDID 327 Query: 235 GLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEV 289 +D F P TGT GGL YRE + + + +T + +D++E NPSL + ++V Sbjct: 328 SVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKV 382 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 19/55 (34%), Positives = 28/55 (50%) Query: 5 SRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIP 59 S+ + IIG+P + GQP GGV+ LRK GL + +D G++ D Sbjct: 23 SKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNGDNE 77 >3NIO-A nrPDB Length = 319 Score = 238 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 71/305 (23%), Positives = 120/305 (39%), Gaps = 28/305 (9%) Query: 8 IGIIGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQI 66 +G P G R G GP +R ++ + + L ADI + Sbjct: 40 AAFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIG-----DV 94 Query: 67 VKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAH 126 N ++ +A + + + +G + L LGGDH++ + + + H +G++ VDAH Sbjct: 95 AINTFNLLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAH 154 Query: 127 TDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR--DVDP 184 D+N HG ++E + +V IGLR Sbjct: 155 ADVND-HMFGEKIAHGTTFRRAVEED---------------LLDCDRVVQIGLRAQGYTA 198 Query: 185 GEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPAT 244 + + G + E + +M E + G P++LSFD+DG+DP++ P T Sbjct: 199 EDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGG---GPVYLSFDIDGIDPAWAPGT 255 Query: 245 GTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACF 304 GTP +GGLT + + I L+ G D++EV+P T N + Sbjct: 256 GTPEIGGLTTIQAMEIIRGCQGLDLI-GCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLP 314 Query: 305 GLARE 309 G+ R Sbjct: 315 GVVRR 319 >3NIP-A nrPDB Length = 326 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 74/280 (26%), Positives = 118/280 (42%), Gaps = 28/280 (10%) Query: 7 TIGIIGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQ 65 +G+IG P+ G R G GP +R L + + Y + D+ D+P Sbjct: 36 QVGLIGVPWDGGTTNRAGARHGPREVRNLSSLMRKVHHVSRIAPYDLVRVGDL-GDAPV- 93 Query: 66 IVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDA 125 NP + + ++ G +V G + L +GGDH + + R P LG++ DA Sbjct: 94 ---NPIDLLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGRERP-LGMVHFDA 149 Query: 126 HTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRD--VD 183 H+D N + HG P ++E + V IG+R Sbjct: 150 HSDTNDRYFGDNPYTHGTPFRRAIEEG---------------LLDPLRTVQIGIRGSVYS 194 Query: 184 PGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPA 243 P + + GI+ M E LG+ + E + P ++SFDVD LDP+F P Sbjct: 195 PDDDAFARECGIRVIHMEEFVELGVEATLAEARRVVGA---GPTYVSFDVDVLDPAFAPG 251 Query: 244 TGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLG 283 TGTP +GG+T + + + L+ G D++EV+P Sbjct: 252 TGTPEIGGMTSLQAQQLVRGLRGLDLV-GADVVEVSPPFD 290 >4DZ4-A nrPDB Length = 324 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 86/303 (28%), Positives = 127/303 (41%), Gaps = 36/303 (11%) Query: 14 PFSKGQP-RGGVEEGPTVLRKAGL-LEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPR 71 P R G GP+ +R A + L +L + DL D D F +P Sbjct: 55 PLDLATTFRSGARLGPSAVRAASVQLAELNPYPWGFDPFDDLAVIDY-GDCWFD-AHHPL 112 Query: 72 SVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPD-LGVIWVDAHTDIN 130 S+ A + A + ++ + R+ L LGGDH + + HA+ + L +I DAH D Sbjct: 113 SIKPAIVEHARTI--LQSDARM-LTLGGDHYITYPLLIAHAQKYGKPLSLIHFDAHCDTW 169 Query: 131 TPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIL 190 S N HG K +K + I K V +G+R + Sbjct: 170 ADDAPDSLN-HGT---MFYKAVKDGL------------IDPKASVQVGIRTWND------ 207 Query: 191 KTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVG 250 LGI V G +E S + GR P +L+FD+D LDP+F P TGTPV G Sbjct: 208 DYLGINVLDAAWVHEHGARATLERIESIVGGR---PAYLTFDIDCLDPAFAPGTGTPVAG 264 Query: 251 GLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREG 310 GL+ + L I + L+ G D++EV P+ ++ E+T VA L C R+ Sbjct: 265 GLSSAQALAIVRGLGGVNLI-GADVVEVAPAYDQS--EITAIAAAHVACDLLCLWRQRKA 321 Query: 311 NHK 313 + Sbjct: 322 GAR 324 >3LHL-A nrPDB Length = 287 Score = 210 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 67/303 (22%), Positives = 117/303 (38%), Gaps = 59/303 (19%) Query: 10 IIGAPFSKGQP-RGGVEEGPTVLRKA-------GLLEKLKEQECDVKDYGDLPFADIPND 61 + G F R G + +RK L ++ ++ DYGDL + Sbjct: 12 VFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEIS----- 66 Query: 62 SPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVI 121 S + +++ + ++ ++ ++ ++GG+H + + + + D+ VI Sbjct: 67 --------VGSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVI 118 Query: 122 WVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRD 181 DAHTD+ S N H + +I D+ G I G+R Sbjct: 119 HFDAHTDLREEYNN-SKNSHATVIK--------RIWDIVG---------DNKIFQFGIRS 160 Query: 182 VDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFT 241 E Y + +D E ++ L G+ I+L+ D+D LD S Sbjct: 161 GTKEEFKFATEEKHTYMEIGGID------TFENIVNMLNGKN---IYLTIDLDVLDASVF 211 Query: 242 PATGTPVVGGLTYREGLYITEEIYKTGL-LSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT 300 P TGTP GG+ YRE I + I + + + G DI+E++P T V+ Sbjct: 212 PGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYD----------TTGVSTV 261 Query: 301 LAC 303 +AC Sbjct: 262 IAC 264 >1GQ7-A nrPDB Length = 313 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 78/288 (27%), Positives = 125/288 (43%), Gaps = 44/288 (15%) Query: 8 IGIIGAPFSKGQP-RGGVEEGPTVLR-KAGLLEKLKEQE-------CDVKDYGDLPFADI 58 + +IGAP+ G R G GP +R ++GL+ + + D GD+ Sbjct: 32 VVVIGAPYDGGTSYRPGARFGPQAIRSESGLIHGVGIDRGPGTFDLINCVDAGDI----- 86 Query: 59 PNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDL 118 N +PF + ++ A L+G + L++GGDHSL + ++ A H L Sbjct: 87 -NLTPFDMN---IAIDTAQSHLSGLLKANAAF----LMIGGDHSLTVAALRAVAEQHGPL 138 Query: 119 GVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIG 178 V+ +DAH+D N P HG P + E I +V IG Sbjct: 139 AVVHLDAHSDTN-PAFYGGRYHHGTPFRHGIDE---------------KLIDPAAMVQIG 182 Query: 179 LRDVDPGEH--YILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGL 236 +R +P + G++ + E LG+G + + +RP+++S D+D + Sbjct: 183 IRGHNPKPDSLDYARGHGVRVVTADEFGELGVGGTADLIREKVG---QRPVYVSVDIDVV 239 Query: 237 DPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGK 284 DP+F P TGTP GGL RE L + + + G D+MEV+P Sbjct: 240 DPAFAPGTGTPAPGGLLSREVLALLRCVGDLKPV-GFDVMEVSPLYDH 286 >4G3H-A nrPDB Length = 330 Score = 208 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 71/314 (22%), Positives = 133/314 (42%), Gaps = 27/314 (8%) Query: 10 IIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKN 69 ++G G + G ++G LR+A +K + F+ KN Sbjct: 3 LVGLEAELGASKRGTDKGVRRLREA----LSATHGDVIKGMQTITQERCVLYKEFRYAKN 58 Query: 70 PRSVGK-ASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPD--LGVIWVDAH 126 E L + EV + L+L +H+ G VH D +G++++DAH Sbjct: 59 FEDYYLFCKENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAH 118 Query: 127 TDINTPLTTTSGNLHGQPVSFLLKELK---GKIPDVPGFSWVTPC----------ISAKD 173 DI+T + S ++HG P+ +L ++ ++ + +W C I K Sbjct: 119 ADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMSESEEKAWQKLCSLGLEKGGLEIDPKC 178 Query: 174 IVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDV 233 +VY G+R + E +++ L I FS+ + R + +V+++T L + I+LS D+ Sbjct: 179 LVYFGVRSTEQSERDVIRELQIPLFSVDAI-RENMQEVVQKTKESL--KAVDIIYLSLDL 235 Query: 234 DGLDPSFTPATGTPVVGGLTYREGLYITEEIYKT--GLLSGLDIMEVNP--SLGKTPEEV 289 D +D +TG GL++ E + + ++ L +++ E NP S+ EE Sbjct: 236 DIMDGKLFTSTGVRENNGLSFDELKQLLGLLLESFKDRLKAVEVTEYNPTVSIKHNNEEE 295 Query: 290 TRTVNTAVAITLAC 303 + + I +C Sbjct: 296 KQVLEILDLIINSC 309 >3M1R-A nrPDB Length = 322 Score = 207 bits (526), Expect = 6e-54, Method: Composition-based stats. Identities = 70/303 (23%), Positives = 121/303 (39%), Gaps = 39/303 (12%) Query: 6 RTIGIIGAPFSKGQ-PRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPND--- 61 + +IG P SK G P +R+A LK + G+ +++ D Sbjct: 38 KGPALIGVPLSKSSISHSGASFAPGTIRQA-----LKHSSAYSAELGEHVVSELLYDLGD 92 Query: 62 ---SPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDL 118 IVK+ + + L + + L+LGGD+S++ +I A+ Sbjct: 93 IDIHVTDIVKSHHHIFQTMHALLSDHPD-----WVPLILGGDNSISYSTIKAIAQTKGTT 147 Query: 119 GVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIG 178 VI DAH D+ T G +G P LL E I + ++ +G Sbjct: 148 AVIQFDAHHDVRN--TEDGGPTNGTPFRRLLDE---------------EIIEGQHLIQLG 190 Query: 179 LRDVDPGEHY--ILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGL 236 +R+ + Y K + +M + G+ ++E L ++ K I +S D+D L Sbjct: 191 IREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILP-VVQDKTDFIFISVDMDVL 249 Query: 237 DPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTA 296 D S P GGL E L + I + ++G++I+EV+P+L ++T Sbjct: 250 DQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLD--FRDMTSRAAAH 307 Query: 297 VAI 299 V + Sbjct: 308 VLL 310 >3PZL-A nrPDB Length = 313 Score = 183 bits (465), Expect = 7e-47, Method: Composition-based stats. Identities = 65/278 (23%), Positives = 110/278 (39%), Gaps = 36/278 (12%) Query: 10 IIGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVK 68 + G PF R G + P +R A + + E + + ++ Sbjct: 39 VFGIPFDNTSSYRRGSKYAPDSIRGAYVNLESYEYSYGIDLLA-------SGMADLGDME 91 Query: 69 NPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTD 128 V + + V+ V +G+I ++LGG+HS+ +G++ + D+ ++ VDAH+D Sbjct: 92 ESEDVEYVIDTVESVVSAVMSDGKIPIMLGGEHSITVGAVRALPK---DVDLVIVDAHSD 148 Query: 129 INTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHY 188 + N H L L I IG+R V E Sbjct: 149 FRSSYMGNKYN-HACVTRRALDLLGEG-----------------RITSIGIRSVSREEFE 190 Query: 189 ILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPV 248 + + S +V + GI K +EE RK R +++S D+DG+DP++ PA GTP Sbjct: 191 DPDFRKVSFISSFDVKKNGIDKYIEEV-----DRKSRRVYISVDMDGIDPAYAPAVGTPE 245 Query: 249 VGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTP 286 GL + + E + G DI+E +P Sbjct: 246 PFGLADTDVRRLIERLSYKA--VGFDIVEFSPLYDNGN 281 >1WOG-A nrPDB Length = 305 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 77/313 (24%), Positives = 119/313 (38%), Gaps = 54/313 (17%) Query: 8 IGIIGAPFSKGQP-RGGVEEGPTVLRKA---------GLLEKLKEQECDVKDYGDLPFAD 57 + +G PF R G P LR+A GL K + Q D GD+ Sbjct: 31 VAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGDV---I 87 Query: 58 IPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPD 117 +P+ P + +A+ Q+ G+ R+ + LGGDHS++ + A V PD Sbjct: 88 LPSLEPQ---LAHDRITEAARQVRGRC-------RVPVFLGGDHSVSYPLLRAFADV-PD 136 Query: 118 LGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYI 177 L V+ +DAH D T + + P + L + I + Sbjct: 137 LHVVQLDAHLDFTDTRNDTKWS-NSSPFRRACEALPNLV----------------HITTV 179 Query: 178 GLRDV--DPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRP--IHLSFDV 233 GLR + DP + G M +V L+ +L + R ++ S DV Sbjct: 180 GLRGLRFDPEAVAAARARGHTIIPMDDV---------TADLAGVLAQLPRGQNVYFSVDV 230 Query: 234 DGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTV 293 DG DP+ P T +P GLTY +G+ I + GLD++E+ P+L T Sbjct: 231 DGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELLMA 290 Query: 294 NTAVAITLACFGL 306 + F Sbjct: 291 RLVMETLCEVFDH 303 >4RHL-A nrPDB Length = 351 Score = 173 bits (439), Expect = 7e-44, Method: Composition-based stats. Identities = 69/305 (22%), Positives = 116/305 (38%), Gaps = 68/305 (22%) Query: 25 EEGPTVL--------RKAGLLEKLKEQECDVKDYGDLPFADI------PNDSPFQIVKNP 70 GP L R+A LL+ + D Y +L D P F V N Sbjct: 42 RLGPVALFGYGAGMPRRAPLLDFFLQSPRDCDHYAELTIHDKGPIECPPETVMFMPVLN- 100 Query: 71 RSVGKASEQLAGK---------------VAEVKKNGRISLVLGGDHSLAIGSISGHARVH 115 G+ ++ AG E+ + G + + +GGD S + + + R+ Sbjct: 101 --CGQMLDEAAGTETPTSDEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLF 158 Query: 116 P--DLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKD 173 P D+ ++ DAH ++ P + P+ LL + K Sbjct: 159 PSDDIVIVHFDAHPSVSDPRS---------PLRVLLDKG-----------------LLKG 192 Query: 174 IVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDV 233 +V +G R V + + K + Y M + G+ + + R P+ +S D Sbjct: 193 VVSVGNRQVSSEDRKVRKLHKMFYMDMHAIYSKGLFCIRDI-------RNDYPVFISIDA 245 Query: 234 DGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTV 293 D LDP+F PA +PV GGL+ R+ L+I I + G+D+ NP L ++ Sbjct: 246 DVLDPAFAPAVDSPVAGGLSTRDLLHIMNGIRGPK-VVGIDVYGYNPDLDVYRKDNVGLT 304 Query: 294 NTAVA 298 A++ Sbjct: 305 AIALS 309 >1XFK-A nrPDB Length = 336 Score = 98.7 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 57/322 (17%), Positives = 107/322 (33%), Gaps = 48/322 (14%) Query: 8 IGIIGAPFSKG----QPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSP 63 + +IG G + R G + P+++++A L + D G++ Sbjct: 45 VALIGFECDAGVERNKGRTGAKHAPSLIKQA-LANLAWHHPIPIYDLGNIRCE------- 96 Query: 64 FQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVH-------P 116 + +A ++ A + + + R ++VLGG H +A + G A+ P Sbjct: 97 ------GDELEQAQQECAQVIQQALPHAR-AIVLGGGHEIAWATFQGLAQHFLATGVKQP 149 Query: 117 DLGVIWVDAHTDINTPLTT--TSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDI 174 +G+I DAH D+ T + G P + + + + D Sbjct: 150 RIGIINFDAHFDLRTFESELAPVRPSSGTPFNQIHHFCQQQGWDF-------------HY 196 Query: 175 VYIGLR--DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFD 232 +G+ P LG+ Y L + + + ++ ++L+ D Sbjct: 197 ACLGVSRASNTPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFIDD--CDYLYLTID 254 Query: 233 VDGLDPSFTPATGTPVVGGLTYREGL--YITEEIYKTGLLSGLDIMEVNPSLGKTPEEVT 290 +D + P P G++ E L Y ++ L DI E NPS Sbjct: 255 LDVFPAASAPGVSAPAARGVSL-EALAPYFDRILHYKNKLMIADIAEYNPSFDIDQHTAR 313 Query: 291 RTVNTAVAITLACFGLAREGNH 312 I A + H Sbjct: 314 LAARLCWDIANAMAEQVQSIRH 335 >3A1K-A nrPDB Length = 521 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 45/120 (37%), Gaps = 9/120 (7%) Query: 8 IGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKD---YGDLPFADIPNDSPF 64 + + G P G R P+ R A ++ +L V DL F+ Sbjct: 99 VTVAGVPMMNG-SRTVEGFTPS--RDATVVTRLLAAGATVAGKAVCEDLCFSGSSFTPAS 155 Query: 65 QIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGD--HSLAIG-SISGHARVHPDLGVI 121 V+NP + + +G A + NG + +GGD S+ I + G P G++ Sbjct: 156 GPVRNPWDRQREAGGSSGGSAALVANGDVDFAIGGDQGGSIRIPAAFCGVVGHKPTFGLV 215 >3TAI-A nrPDB Length = 471 Score = 30.9 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 44/121 (36%), Gaps = 11/121 (9%) Query: 202 EVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYIT 261 EV GK ++E L L K ++L D D D L+Y E LY Sbjct: 255 EVLESSRGKSVDELLQELDEEKVE-LYLGKD-DIYDALHMT---------LSYIEYLYSI 303 Query: 262 EEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPP 321 +++ + L+ + +L +T A+ G +EG + + PP Sbjct: 304 DKLLEVKNLAYIAKSFYTKTLARTLGVEIVDTALLDAVIRTLIGHEKEGYLEIEHAVVPP 363 Query: 322 K 322 K Sbjct: 364 K 364 >1GKH-A nrPDB Length = 87 Score = 29.4 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 25/57 (43%) Query: 190 LKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGT 246 +K ++ + + V R G + E L Y+ + P+ + +D P++ P T Sbjct: 6 IKPSQAQFTTRSGVSRQGKPYSLNEQLCYVDLGNEYPVLVKITLDEGQPAYAPGLYT 62 >3VUE-A nrPDB Length = 536 Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 24/65 (36%), Gaps = 1/65 (1%) Query: 256 EGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPI 315 E I TG+++G+D+ E +PS K A L L E P+ Sbjct: 265 ELDNIMRLTGITGIVNGMDVSEWDPSKDKYITAKYDATTAIEAKALNKEALQAEAG-LPV 323 Query: 316 DYLNP 320 D P Sbjct: 324 DRKIP 328 >5M7N-A nrPDB Length = 454 Score = 28.2 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 28/82 (34%) Query: 51 GDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISG 110 ++ D+ R+ A LA + + + L G + + Sbjct: 11 DEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDE 70 Query: 111 HARVHPDLGVIWVDAHTDINTP 132 + HP+L V+ + H +I T Sbjct: 71 IKKQHPELPVVMISGHGNIETA 92 >4D6Y-A nrPDB Length = 148 Score = 27.8 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 28/82 (34%) Query: 51 GDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISG 110 ++ D+ R+ A LA + + + L G + + Sbjct: 24 DEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRLDGLALLDE 83 Query: 111 HARVHPDLGVIWVDAHTDINTP 132 + HP+L V+ + H +I T Sbjct: 84 IKKQHPELPVVMISGHGNIETA 105 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.123 0.319 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,588,701 Number of Sequences: 36641 Number of extensions: 453580 Number of successful extensions: 1430 Number of sequences better than 10.0: 31 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1263 Number of HSP's gapped (non-prelim): 79 length of query: 322 length of database: 10,336,785 effective HSP length: 97 effective length of query: 225 effective length of database: 6,782,608 effective search space: 1526086800 effective search space used: 1526086800 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.4 bits)