BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P04905 (218 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5FWG-A nrPDB 452 e-128 1B4P-A nrPDB 400 e-112 1XWK-A nrPDB 379 e-106 2DC5-A nrPDB 367 e-102 1HNA-A nrPDB 365 e-102 4GTU-A nrPDB 353 3e-98 3GTU-B nrPDB 325 1e-89 1GSU-A nrPDB 287 3e-78 5AN1-A nrPDB 246 4e-66 2FHE-A nrPDB 207 3e-54 4Q5Q-A nrPDB 203 5e-53 2WRT-A nrPDB 196 5e-51 1FHE-A nrPDB 185 1e-47 1BG5-A nrPDB 165 1e-41 1B8X-A nrPDB 164 3e-41 1DUG-A nrPDB 164 3e-41 4WR5-A nrPDB 159 1e-39 2GSR-A nrPDB 108 2e-24 18GS-A nrPDB 106 7e-24 2GLR-A nrPDB 105 1e-23 1TU7-A nrPDB 103 4e-23 5D73-A nrPDB 103 4e-23 3KXO-A nrPDB 76 1e-14 5Y9Z-A nrPDB 76 1e-14 2AAW-A nrPDB 74 4e-14 4Q5R-A nrPDB 74 4e-14 1M0U-A nrPDB 69 1e-12 1F3B-A nrPDB 60 7e-10 1EV4-A nrPDB 60 1e-09 5LCZ-A nrPDB 59 2e-09 2CA8-A nrPDB 58 3e-09 4Q5F-A nrPDB 56 1e-08 1ZL9-A nrPDB 56 1e-08 1YQ1-A nrPDB 55 2e-08 2VCV-A nrPDB 55 3e-08 3I6A-A nrPDB 55 3e-08 1GSQ-A nrPDB 54 6e-08 1PL2-A nrPDB 52 2e-07 2VCT-A nrPDB 52 3e-07 1U3I-A nrPDB 52 3e-07 2WDU-A nrPDB 51 4e-07 1B48-A nrPDB 50 8e-07 1GUL-A nrPDB 42 2e-04 6F05-A nrPDB 42 2e-04 5F07-A nrPDB 42 3e-04 4MPF-A nrPDB 39 0.002 4MDC-A nrPDB 38 0.004 2HNL-A nrPDB 37 0.006 5ZWP-A nrPDB 35 0.020 1VF1-A nrPDB 35 0.021 5F0G-A nrPDB 34 0.044 5J5N-A nrPDB 34 0.060 5ECL-B nrPDB 33 0.077 5GJQ-x nrPDB 32 0.16 2AYN-A nrPDB 32 0.17 4CHS-A nrPDB 32 0.18 4PNG-A nrPDB 32 0.24 1AXD-A nrPDB 32 0.24 3VWX-A nrPDB 32 0.31 2VO4-A nrPDB 31 0.39 1PN9-A nrPDB 30 0.80 2C3Q-A nrPDB 30 1.0 1AW9-A nrPDB 30 1.1 1JLV-A nrPDB 29 1.3 3MAK-A nrPDB 29 1.5 1GPI-A nrPDB 29 1.8 4S35-A nrPDB 28 2.2 3LFL-A nrPDB 28 2.3 4HQS-A nrPDB 28 2.3 4EVM-A nrPDB 28 2.6 5WZE-A nrPDB 28 2.8 2QB5-A nrPDB 28 3.9 3E9K-A nrPDB 27 6.5 4MTN-A nrPDB 27 6.6 1V2A-A nrPDB 27 8.9 >5FWG-A nrPDB Length = 217 Score = 452 bits (1163), Expect = e-128, Method: Compositional matrix adjust. Identities = 217/217 (100%), Positives = 217/217 (100%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 120 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL Sbjct: 121 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 180 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK Sbjct: 181 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >1B4P-A nrPDB Length = 217 Score = 400 bits (1028), Expect = e-112, Method: Compositional matrix adjust. Identities = 185/217 (85%), Positives = 205/217 (94%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIR D++ENQ MD R+QL M+CY+PDFE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFE 120 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 ++KPE+L+ +PEKMKLYSEFLGK+PWFAG+K+TYVDFL YD+LDQ+ IFEPKCLDAFPNL Sbjct: 121 RKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNL 180 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 KDF+ARFEGLKKIS YMKS R+LS PIF+K+A W+ K Sbjct: 181 KDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >1XWK-A nrPDB Length = 218 Score = 379 bits (973), Expect = e-106, Method: Compositional matrix adjust. Identities = 173/218 (79%), Positives = 200/218 (91%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPMILGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNL Sbjct: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PYLIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IR DI+ENQ MDN MQL M+CYNP+F Sbjct: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 EK KP++L+ +PEK+KLYSEFLGKRPWFAG+K+T+VDFL YD+LD + IFEPKCLDAFPN Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 LKDF++RFEGL+KISAYMKSSR+L P+FSK+A W NK Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >2DC5-A nrPDB Length = 231 Score = 367 bits (941), Expect = e-102, Method: Compositional matrix adjust. Identities = 167/217 (76%), Positives = 192/217 (88%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPM LGYW++RGL H IRL LEYTDSSYEEKRY MGDAPDYD+SQWLNEKFKLGLDFPNL Sbjct: 8 MPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNL 67 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PYLIDGS KITQSNAI+RYL RKH+LCGETEEERIR DI+ENQ+MDNRM L LCYN DF Sbjct: 68 PYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADF 127 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 EK KP +L+ +P M+LYSEFLGKRPWFAGDK+T+VDF+AYD+L++ +FE KCLDAFPN Sbjct: 128 EKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPN 187 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 LKDF+ARFEGLKKIS YMK+SR+L P+F+K+A W + Sbjct: 188 LKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGS 224 >1HNA-A nrPDB Length = 217 Score = 365 bits (937), Expect = e-102, Method: Compositional matrix adjust. Identities = 164/217 (75%), Positives = 197/217 (90%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PM LGYWN+RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YLIDG+ KITQSNAI+RY+ARKH+LCGE+E+E+IR DI+ENQ MD+RMQL LCY+PDFE Sbjct: 61 YLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFE 120 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 K KPE+L+ +PE +KLYS+FLGK+PWF GDK+T+VDF+AYD+L++ +FEP CLDAFPNL Sbjct: 121 KLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNL 180 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 KDF++RFEGL+KISAYMKSSR+L P+F+K+A + NK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >4GTU-A nrPDB Length = 217 Score = 353 bits (906), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 160/216 (74%), Positives = 190/216 (87%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M LGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLPY Sbjct: 2 MTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 61 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 LIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IR DI+ENQ MD QL +CY+PDFEK Sbjct: 62 LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEK 121 Query: 123 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 KPE+L+ +P M+ +S+FLGKRPWF GDK+T+VDFLAYD+LD + IFEP CLDAFPNLK Sbjct: 122 LKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNLK 181 Query: 183 DFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 DF++RFEGL+KISAYMKSSR+L P+++++A W NK Sbjct: 182 DFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >3GTU-B nrPDB Length = 224 Score = 325 bits (832), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 147/216 (68%), Positives = 182/216 (84%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M+LGYW++RGL H IRLLLE+TD+SYEEKRY G+APDYDRSQWL+ KFKL LDFPNLPY Sbjct: 6 MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 65 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 L+DG KITQSNAI+RY+ARKH++CGETEEE+IR DI+ENQVMD R QLI LCY+ D EK Sbjct: 66 LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 125 Query: 123 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 KP++L+ +P ++K +S FLGK WFAG+K+T+VDFL YDILDQ IF+PKCLD FPNLK Sbjct: 126 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 185 Query: 183 DFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 F+ RFE L+KI+AY++S ++ PI +K+AQW NK Sbjct: 186 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >1GSU-A nrPDB Length = 219 Score = 287 bits (734), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 132/216 (61%), Positives = 165/216 (76%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 + LGYW++RGL H IRLLLEYT++ Y+E+RY G APD+D S W NEK KLGLDFPNLPY Sbjct: 2 VTLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPY 61 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 LIDG K+TQSNAI+RY+ARKH++CGETE E+ R D++EN +MD RM LCY+PDFEK Sbjct: 62 LIDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEK 121 Query: 123 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 KP +L+ +P K++ S FLG R WF GDK+T+VDFLAYD+LDQ +F P C + NL Sbjct: 122 LKPAYLEQLPGKLRQLSRFLGSRSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQGNLS 181 Query: 183 DFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FL RFE L+KISAYM+S R++ PIF A W+NK Sbjct: 182 QFLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >5AN1-A nrPDB Length = 219 Score = 246 bits (629), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 117/213 (54%), Positives = 149/213 (69%), Gaps = 2/213 (0%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 +LGYW R L PIRL+L YT + +EEK Y +GDAPDYD+S+WL KFKLGL FPNLPY Sbjct: 4 VLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPYY 63 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG KITQS AIMRYLARKH LCG T EE +R D++E Q+ D + Y + +Q Sbjct: 64 IDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTY--EHYEQ 121 Query: 124 KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKD 183 K + ++P K++ YS+FLG RPWFAGDK+TY+DFLAY+I DQ+ + CLD F NL+ Sbjct: 122 KDAYTASLPAKLRQYSDFLGSRPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDGFKNLQA 181 Query: 184 FLARFEGLKKISAYMKSSRYLSTPIFSKLAQWS 216 F RFE L+ I YM S ++L PI +K AQ++ Sbjct: 182 FQKRFEDLEAIKKYMASPKFLKKPICNKYAQFT 214 >2FHE-A nrPDB Length = 216 Score = 207 bits (527), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 100/216 (46%), Positives = 136/216 (62%), Gaps = 5/216 (2%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW +RGL P+RLLLEY YEE+ Y D +W ++KF+LGLD PNLP Sbjct: 1 PAKLGYWKIRGLQQPVRLLLEYLGEKYEEQIYERDDG-----EKWFSKKFELGLDLPNLP 55 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 Y ID K+TQS AI+RY+A KH + G T EER R ++E +D R + + Y P FE Sbjct: 56 YYIDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFE 115 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 + K +LK +P MK++S+FLGK P+ G V++VDF+ Y+ LD EP CLD FPNL Sbjct: 116 QLKEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNL 175 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 + F++R E L I AYM+S+R++ P+ AQ+ Sbjct: 176 QQFMSRIEALPSIKAYMESNRFIKWPLNGWHAQFGG 211 >4Q5Q-A nrPDB Length = 219 Score = 203 bits (516), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 94/199 (47%), Positives = 134/199 (67%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYW++RG PIRLLL Y+ + +KRY +G APD+DRS+WLNEKF LGLDFPNLPY Sbjct: 5 ILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPYY 64 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG K+TQ+ AI+RYL RK+ L G + E IR + E Q D +I +CY+ + +K Sbjct: 65 IDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANCDKL 124 Query: 124 KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKD 183 KP++LK++P+ +KL S+F+G+ + AG ++YVDF Y+ L + P+ F NLK Sbjct: 125 KPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVPEVFGQFENLKR 184 Query: 184 FLARFEGLKKISAYMKSSR 202 ++ R E L ++S Y+K + Sbjct: 185 YVERMESLPRVSDYIKKQQ 203 >2WRT-A nrPDB Length = 218 Score = 196 bits (499), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 103/217 (47%), Positives = 138/217 (63%), Gaps = 5/217 (2%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MP LGYW +RGL P+RLLLEY YEE Y D R +WL +KF +GLD PNL Sbjct: 1 MPAKLGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRDD-----REKWLGDKFNMGLDLPNL 55 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PY ID K+TQS AIMRY+A KH + G T EER R ++E MD RM + +CYNP F Sbjct: 56 PYYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCYNPKF 115 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 E+ K ++LK +P +K++S FLG R + G V++VDF+ Y+ LD P+CL+ FP Sbjct: 116 EEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPK 175 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 LK+F +R E L KI AYM+S +++ P+ S +A + Sbjct: 176 LKEFKSRIEDLPKIKAYMESEKFIKWPLNSWIASFGG 212 >1FHE-A nrPDB Length = 217 Score = 185 bits (470), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 100/207 (48%), Positives = 133/207 (64%), Gaps = 5/207 (2%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW +RGL P+RL LEY YEE Y D R +W++EKF +GLD PNLP Sbjct: 1 PAKLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDD-----REKWMSEKFNMGLDLPNLP 55 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 Y ID K+TQS AIMRY+A KH + G T EER R ++E MD R+ +CYNP FE Sbjct: 56 YYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNPKFE 115 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 + K E++K +P+ +K++S+FLG R + G V++VDF+ Y+ LD P CLD FP L Sbjct: 116 EVKEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPKL 175 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPI 208 K+F +R E L KI AYM+S R++ P+ Sbjct: 176 KEFKSRIEALPKIKAYMESKRFIKWPL 202 >1BG5-A nrPDB Length = 254 Score = 165 bits (418), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 92/208 (44%), Positives = 130/208 (62%), Gaps = 5/208 (2%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M ILGYW ++GL P RLLLEY + YEE Y + +W N+KF+LGL+FPNL Sbjct: 1 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNL 55 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PY IDG K+TQS AI+RY+A KH++ G +ER ++E V+D R + + Y+ DF Sbjct: 56 PYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDF 115 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 E K +FL +PE +K++ + L + + GD VT+ DF+ YD LD +P CLDAFP Sbjct: 116 ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 175 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPI 208 L F R E + +I Y+KSS+Y++ P+ Sbjct: 176 LVCFKKRIEAIPQIDKYLKSSKYIAWPL 203 >1B8X-A nrPDB Length = 280 Score = 164 bits (415), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 91/205 (44%), Positives = 129/205 (62%), Gaps = 5/205 (2%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYW ++GL P RLLLEY + YEE Y + +W N+KF+LGL+FPNLPY Sbjct: 3 ILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLPYY 57 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG K+TQS AI+RY+A KH++ G +ER ++E V+D R + + Y+ DFE Sbjct: 58 IDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETL 117 Query: 124 KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKD 183 K +FL +PE +K++ + L + + GD VT+ DF+ YD LD +P CLDAFP L Sbjct: 118 KVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVC 177 Query: 184 FLARFEGLKKISAYMKSSRYLSTPI 208 F R E + +I Y+KSS+Y++ P+ Sbjct: 178 FKKRIEAIPQIDKYLKSSKYIAWPL 202 >1DUG-A nrPDB Length = 234 Score = 164 bits (415), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 91/205 (44%), Positives = 129/205 (62%), Gaps = 5/205 (2%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYW ++GL P RLLLEY + YEE Y + +W N+KF+LGL+FPNLPY Sbjct: 3 ILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLPYY 57 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG K+TQS AI+RY+A KH++ G +ER ++E V+D R + + Y+ DFE Sbjct: 58 IDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETL 117 Query: 124 KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKD 183 K +FL +PE +K++ + L + + GD VT+ DF+ YD LD +P CLDAFP L Sbjct: 118 KVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVC 177 Query: 184 FLARFEGLKKISAYMKSSRYLSTPI 208 F R E + +I Y+KSS+Y++ P+ Sbjct: 178 FKKRIEAIPQIDKYLKSSKYIAWPL 202 >4WR5-A nrPDB Length = 244 Score = 159 bits (402), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 88/205 (42%), Positives = 125/205 (60%), Gaps = 5/205 (2%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 ILGYW ++GL P RLLLE + YEE + +W N+KF+LGL+FPNLPY Sbjct: 28 ILGYWKIKGLVQPTRLLLEXLEEKYEEHLXERDEG-----DKWRNKKFELGLEFPNLPYX 82 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG K+TQS AI+R +A KH++ G +ER ++E V+D R + + Y+ DFE Sbjct: 83 IDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETL 142 Query: 124 KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKD 183 K +FL +PE +K++ + L + GD VT+ DF+ YD LD +P CLDAFP L Sbjct: 143 KVDFLSKLPEMLKMFEDRLCHKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAFPKLVC 202 Query: 184 FLARFEGLKKISAYMKSSRYLSTPI 208 F R E + +I Y+KSS+Y++ P+ Sbjct: 203 FKKRIEAIPQIDKYLKSSKYIAWPL 227 >2GSR-A nrPDB Length = 207 Score = 108 bits (269), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 66/211 (31%), Positives = 107/211 (50%), Gaps = 15/211 (7%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ VRG +R+LL D S++E+ M P K F LP Sbjct: 2 PYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTMETWP----------PLKPSCLFRQLP 51 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 DG + QSNAI+R+L R L G+ ++E D+V + V D R + L Y ++E Sbjct: 52 KFQDGDLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYT-NYE 110 Query: 122 KQKPEFLKTIPEKMK----LYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 K +++K +PE +K L S+ G + + G ++++ D+ D+L + + P CLDA Sbjct: 111 AGKEKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDA 170 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 FP L ++AR KI A++ S +++ PI Sbjct: 171 FPLLSAYVARLSARPKIKAFLASPEHVNRPI 201 >18GS-A nrPDB Length = 210 Score = 106 bits (265), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 62/211 (29%), Positives = 106/211 (50%), Gaps = 13/211 (6%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ VRG +R+LL S++E+ + W K + LP Sbjct: 3 PYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLP 54 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 DG + QSN I+R+L R L G+ ++E D+V + V D R + I L Y ++E Sbjct: 55 KFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYE 113 Query: 122 KQKPEFLKTIPEKMK----LYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 K +++K +P ++K L S+ G + + GD++++ D+ D+L + + P CLDA Sbjct: 114 AGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDA 173 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 FP L ++ R K+ A++ S Y++ PI Sbjct: 174 FPLLSAYVGRLSARPKLKAFLASPEYVNLPI 204 >2GLR-A nrPDB Length = 209 Score = 105 bits (262), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 62/211 (29%), Positives = 107/211 (50%), Gaps = 13/211 (6%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ VRG +R+LL S++E+ + W+ K + LP Sbjct: 2 PYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTI--------DTWMQGLLKPTCLYGQLP 53 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 DG + QSNAI+R+L R L G+ + E + D+V + V D R + + L Y ++E Sbjct: 54 KFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYT-NYE 112 Query: 122 KQKPEFLKTIPEKMK----LYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 K +++K +P +K L S+ G + + GD++++ D+ D+L + + P CLD Sbjct: 113 NGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDN 172 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 FP L ++AR KI A++ S +++ PI Sbjct: 173 FPLLSAYVARLSARPKIKAFLSSPEHVNRPI 203 >1TU7-A nrPDB Length = 208 Score = 103 bits (258), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 70/213 (32%), Positives = 107/213 (50%), Gaps = 16/213 (7%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+++RGL PIRL L D + + R A D +SQ+ F L Sbjct: 1 MSYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRIAKDDFSSI-KSQF---------QFGQL 50 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 P L DG ++I QS AI+R+LARK++L GE E E D+ V D ++ + Y + Sbjct: 51 PCLYDGDQQIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMA-Y 109 Query: 121 EKQKPEFLKTI-PEKMKLYSEFLGKRP----WFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 E +K ++K+I P ++ + + L R GDK++Y D+ ++ LD + I +P CL Sbjct: 110 ETEKDPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCL 169 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 D FP LK F R + K+ Y + P+ Sbjct: 170 DKFPLLKVFHQRMKDRPKLKEYCEKRDAAKVPV 202 >5D73-A nrPDB Length = 208 Score = 103 bits (258), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 68/213 (31%), Positives = 101/213 (47%), Gaps = 16/213 (7%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+ +RGL PIRL+L + + R D P K F L Sbjct: 1 MSYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWP----------SMKSHFHFGQL 50 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 P L DG +I QS AI+R+LARKH+L G E E D+ V D + + Y + Sbjct: 51 PCLYDGDHQIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQA-Y 109 Query: 121 EKQKPEFLKTI-PEKMKLYSEFLGKRP----WFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 + +K ++K I P ++ + + L R + G+K++YVDF+ ++ LD + I +P CL Sbjct: 110 DTEKDSYIKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCL 169 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 D FP LK + R E + Y K P+ Sbjct: 170 DKFPLLKAYHQRMEDRPGLKEYCKQRNRAKIPV 202 >3KXO-A nrPDB Length = 202 Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 57/202 (28%), Positives = 85/202 (42%), Gaps = 22/202 (10%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+N+RG IR + Y D YE+ R D P+ K L F +P L Sbjct: 9 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 58 Query: 65 DGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCY-----NPD 119 + QS AI RYL + L G TE E+ D + + + D M C+ D Sbjct: 59 VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDD-----FMSCFPWAEKKQD 113 Query: 120 FEKQKPEFLKT--IPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 ++Q L T P M+ +LG R W G+ VT+ DF +F+P LD Sbjct: 114 VKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN 173 Query: 178 FPNLKDFLARFEGLKKISAYMK 199 P L + + + ++ ++K Sbjct: 174 HPRLVTLRKKVQAIPAVANWIK 195 >5Y9Z-A nrPDB Length = 199 Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 61/198 (30%), Positives = 91/198 (45%), Gaps = 16/198 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+N+RG IR + Y D YE+ R D P K K L F +P L Sbjct: 6 LLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWP----------KIKPTLPFGKIPVLE 55 Query: 65 DGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLC-YNPDFEKQ 123 + QS AI RYL + L G+TE E+ + D V + +D+ M L N D +++ Sbjct: 56 VEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVD-TLDDFMSLFPWAEENQDLKER 114 Query: 124 KPEFLKT--IPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILD-QYHIFEPKCLDAFPN 180 L T P +K +LG + WF G+ VT+ DF +DI + +P L +P Sbjct: 115 TFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFY-WDICSTTLLVLKPDLLGIYPR 173 Query: 181 LKDFLARFEGLKKISAYM 198 L + + + ISA++ Sbjct: 174 LVSLRNKVQAIPAISAWI 191 >2AAW-A nrPDB Length = 222 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 63/216 (29%), Positives = 100/216 (46%), Gaps = 24/216 (11%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAM-GDAPDYDRSQWLNEKFKLGLDFPNLP 61 ++L Y++ RG IRL+ Y Y +KR+ + GDA ++ N K + F +P Sbjct: 16 IVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDA----FVEFKNFKKEKDTPFEQVP 71 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPD-- 119 L G + QS AI+RYL++K+++CGE+E AD++ V D I +N Sbjct: 72 ILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQD-----IHYKFNNTNL 126 Query: 120 FEKQKPEFLKTIPEKMKLYSEFLGKRP---------WFAGDKVTYVDFLAYDILDQYHIF 170 F++ + FL K Y E L K+ +F G+ +TY D +++ D Sbjct: 127 FKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETK 186 Query: 171 EPKCLDAFPNLK---DFLARFEGLKKISAYMKSSRY 203 P L FP LK +F++ +K K S Y Sbjct: 187 YPSSLKNFPLLKAHNEFISNLPNIKNYITNRKESVY 222 >4Q5R-A nrPDB Length = 204 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 95/201 (47%), Gaps = 18/201 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y V+ L PIR LL Y + +E+ R+ GD P+ K + F P L Sbjct: 7 LTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPN----------LKPSMPFGKTPVLE 56 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPD-FEK 122 IDG ++ QS AI RYL ++ L G+ + E + D++ + + D R + Y+ D K Sbjct: 57 IDG-KQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSK 115 Query: 123 QK---PEFLKTIPEKMKLYSEFL-GKRPWFAGDKVTYVDFLAYDILDQY-HIFEPKCLDA 177 QK P +TIP K + E + + A K+T+ DF ILD H+ + + Sbjct: 116 QKKWDPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVAN 175 Query: 178 FPNLKDFLARFEGLKKISAYM 198 PNLK + GL I A++ Sbjct: 176 QPNLKALREKVLGLPAIKAWV 196 >1M0U-A nrPDB Length = 249 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 54/202 (26%), Positives = 97/202 (48%), Gaps = 18/202 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+NV+ L P+R L Y + YE+ R R +W K + +P L Sbjct: 52 LFYFNVKALAEPLRYLFAYGNQEYEDVRVT--------RDEW--PALKPTMPMGQMPVLE 101 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 +DG R + QS ++ R+LA+ LCG T E ++ DIV + + D R+++ ++ Y P+ E + Sbjct: 102 VDGKR-VHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDEIK 160 Query: 124 KPEFLKTIPEKMKLYSEFLGKR-----PWFAGDKVTYVDFLAYDILD-QYHIFEPKCLDA 177 + + + E + Y E L + A K+T+ D I D ++ + L+ Sbjct: 161 EKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALGKLTWADVYFAGITDYMNYMVKRDLLEP 220 Query: 178 FPNLKDFLARFEGLKKISAYMK 199 +P L+ + L+ I A+++ Sbjct: 221 YPALRGVVDAVNALEPIKAWIE 242 >1F3B-A nrPDB Length = 222 Score = 60.1 bits (144), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 61/224 (27%), Positives = 101/224 (45%), Gaps = 20/224 (8%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKL--GLDFPNLP 61 +L Y+N RG IR LL +EEK + +S EK K L F +P Sbjct: 5 VLHYFNARGRMECIRWLLAAAGVEFEEK---------FIQSPEDLEKLKKDGNLMFDQVP 55 Query: 62 YL-IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMD--NRMQLIMLCYNP 118 + IDG K+ Q+ AI+ Y+A K+ L G+ +ER D+ ++D + ++LC P Sbjct: 56 MVEIDGM-KLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLC-PP 113 Query: 119 DFEKQKPEFLK--TIPEKMKLYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKC 174 D + K K T + + + L + + G+++T VD ++L F+ Sbjct: 114 DQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASL 173 Query: 175 LDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 L FP LK F +R L + +++ P+ +K Q + K Sbjct: 174 LTPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARK 217 >1EV4-A nrPDB Length = 221 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 18/223 (8%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKL--GLDFPNLP 61 +L Y+N RG IR LL ++EK + +S EK K L F +P Sbjct: 5 VLHYFNARGRMECIRFLLAAAGVEFDEK---------FIQSPEDLEKLKKDGNLMFDQVP 55 Query: 62 YL-IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 + IDG K+ Q+ AI+ Y+A K+ L G+ +ER D+ ++D ++ L P Sbjct: 56 MVEIDGM-KLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPD 114 Query: 121 EKQKPEFL---KTIPEKMKLYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 +K+ L +T + + + L + + G+K+T VD ++L F+ L Sbjct: 115 QKEAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFDASLL 174 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 +FP LK F +R L + +++ P+ +K + + K Sbjct: 175 TSFPLLKAFKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARK 217 >5LCZ-A nrPDB Length = 222 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 54/201 (26%), Positives = 96/201 (47%), Gaps = 14/201 (6%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+N RG R LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG K+ Q+ AI+ Y+A K++L G+ +ER D+ ++D +I L P +++ Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQRE 118 Query: 124 KPEFL---KTIPEKMKLYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAF 178 L +T + + + L + + G+++T VD ++L F+ L +F Sbjct: 119 AKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLLTSF 178 Query: 179 PNLKDFLARFEGLKKISAYMK 199 P LK F +R L + +++ Sbjct: 179 PLLKAFKSRISSLPNVKKFLQ 199 >2CA8-A nrPDB Length = 211 Score = 57.8 bits (138), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 30/175 (17%) Query: 7 YWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY--LI 64 Y+N RG IR+ L +YE++R + D P K K + LP + Sbjct: 10 YFNGRGRAESIRMTLVAAGVNYEDERISFQDWP----------KIKPTIPGGRLPAVKIT 59 Query: 65 DGSRKI---TQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 D + +S AI RY+A+KHH+ G TEEE + + Q D + P+ E Sbjct: 60 DNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEE 119 Query: 122 KQK----------PEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQ 166 KQK P L I E +K + L GDKVT D + ++D Sbjct: 120 KQKIIKEILNGKVPVLLDIICESLKASTGKLA-----VGDKVTLADLVLIAVIDH 169 >4Q5F-A nrPDB Length = 218 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 56/204 (27%), Positives = 83/204 (40%), Gaps = 21/204 (10%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+++RGL RL+ +E+ R D P K F LP L Sbjct: 18 LTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWP----------ALKPKTPFGQLPLLE 67 Query: 65 DGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYN--PDFEK 122 + QS AI RYL R+ L G+T E + D + +Q D M + C+ FE+ Sbjct: 68 VDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDF-MAELRPCFRVLAGFEE 126 Query: 123 -QKPEFLK--TIPEKMK---LYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKC 174 K + LK +P + K L +FL K + G VT+ D + D L + P Sbjct: 127 GDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDF 186 Query: 175 LDAFPNLKDFLARFEGLKKISAYM 198 L LK ++ L I ++ Sbjct: 187 LSGHLQLKKYIEHVRELPNIKKWI 210 >1ZL9-A nrPDB Length = 207 Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 53/207 (25%), Positives = 87/207 (42%), Gaps = 22/207 (10%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+N RG R + Y YE+ R + QW K F LP+L Sbjct: 6 LTYFNGRGAGEVSRQIFAYAGQQYEDNRVT--------QEQWPALKETCAAPFGQLPFLE 57 Query: 65 DGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQL-----IMLCYNP- 118 +K+ QS+AI R+LAR+ L G+T E + + + +Q D + ++ + P Sbjct: 58 VDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPG 117 Query: 119 DFEKQKPEFLKTIPEKMKLYS---EFL--GKRPWFAGDKVTYVDFLAYDILDQYHIFEPK 173 D E K + +P K Y FL + GD +T++D LA I + Sbjct: 118 DVETLKKDIF--LPAFEKFYGFLVNFLKASGSGFLVGDSLTWID-LAIAQHSADLIAKGG 174 Query: 174 CLDAFPNLKDFLARFEGLKKISAYMKS 200 FP LK + + + +I ++++ Sbjct: 175 DFSKFPELKAHAEKIQAIPQIKKWIET 201 >1YQ1-A nrPDB Length = 208 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 59/215 (27%), Positives = 87/215 (40%), Gaps = 28/215 (13%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+ RGL PIRLL +EE R PD WL+ K LP L Sbjct: 6 LTYFFFRGLGEPIRLLFHLAGVQFEEVRMN----PD---QTWLD--IKDSTPMKQLPVLN 56 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYN------ 117 IDG ++ QS AI+RYLARK G+T EE D V + D + Sbjct: 57 IDGF-ELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKS 115 Query: 118 -PDFEKQKPEFLKTIPEKMKLYSEFLG-----KRPWFAGDKVTYVDFLAYD---ILDQYH 168 + EK + EF +P + ++ G + G +T+ D + D L Y Sbjct: 116 AEEVEKFRSEFF--LPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYG 173 Query: 169 IFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRY 203 +F+ L++ + + G+K+ A + Y Sbjct: 174 LFDESEFTKLAALREKVNSYPGIKEYIAKRPVTEY 208 >2VCV-A nrPDB Length = 222 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 59/223 (26%), Positives = 100/223 (44%), Gaps = 20/223 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+N RG PIR LL +EEK +G A D + + N+ L F +P + Sbjct: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMD-NRMQLIMLCYNPDFEK 122 IDG K+ Q+ AI+ Y+A K++L G+ +ER D+ + D N M L++ P+ Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE--- 115 Query: 123 QKPEFLKTIPEKMK-----LYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 +K + I EK K + + L + + G+K++ D ++L + + Sbjct: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP LK R L + +++ P +K + + K Sbjct: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 >3I6A-A nrPDB Length = 222 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 56/203 (27%), Positives = 94/203 (46%), Gaps = 18/203 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+N RG R LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYFNGRGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG K+ Q+ AI+ Y+A K++L G+ +ER D+ + D +IML + P EK Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKD 118 Query: 124 KPEFLKTIPEKMK-----LYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCLD 176 L I EK+K + + L + + G+K++ D ++L + + Sbjct: 119 AK--LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS 176 Query: 177 AFPNLKDFLARFEGLKKISAYMK 199 +FP LK R L + +++ Sbjct: 177 SFPLLKALKTRISNLPTVKKFLQ 199 >1GSQ-A nrPDB Length = 202 Score = 53.5 bits (127), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 22/204 (10%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+ + G R +L + ++ M D P+ + + N +P L Sbjct: 5 LHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNA----------MPVLD 54 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG+ K++QS I R+LAR+ L G+T E+ R D + + D ++ + + P+ K+ Sbjct: 55 IDGT-KMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKE 113 Query: 124 KPEFLKTIPEKMKLYSEFL--------GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 + + + K + FL G +F G+ +T D Y L+ P+ L Sbjct: 114 AVQ--QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELL 171 Query: 176 DAFPNLKDFLARFEGLKKISAYMK 199 P + R KI+AY+K Sbjct: 172 KDCPKIVALRKRVAECPKIAAYLK 195 >1PL2-A nrPDB Length = 222 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 57/222 (25%), Positives = 98/222 (44%), Gaps = 18/222 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+N RG R LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG K+ Q AI+ Y+A K++L G+ +ER D+ + D +++L P EK Sbjct: 60 IDGM-KLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKD 118 Query: 124 KPEFLKTIPEKMK-----LYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCLD 176 L I EK+K + + L + + G+K++ D ++L + + Sbjct: 119 AK--LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLIS 176 Query: 177 AFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 +FP LK R L + +++ P+ K + + K Sbjct: 177 SFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARK 218 >2VCT-A nrPDB Length = 222 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 58/223 (26%), Positives = 100/223 (44%), Gaps = 20/223 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y N+RG IR LL +EEK + A D D+ + N+ + L F +P + Sbjct: 7 LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMD-NRMQLIMLCYNPDFEK 122 IDG K+ Q+ AI+ Y+A K++L G+ +E+ D+ + D M L++ P+ + Sbjct: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQD 118 Query: 123 QKPEFLKTIPEKMK-----LYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 K L I EK K + + L + + G+K++ D ++L + + Sbjct: 119 AK---LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI 175 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 +FP LK R L + +++ P+ K + S K Sbjct: 176 SSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 >1U3I-A nrPDB Length = 211 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/175 (28%), Positives = 72/175 (41%), Gaps = 30/175 (17%) Query: 7 YWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI-- 64 Y++ RG IR+ L YE++R + D P K K + LP + Sbjct: 10 YFDGRGRAESIRMTLVAAGVDYEDERISFQDWP----------KIKPTIPGGRLPAVKVT 59 Query: 65 --DGSRK-ITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 G K + +S AI RY+A+KHH+ GET+EE + + Q D + P E Sbjct: 60 DDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEE 119 Query: 122 KQK----------PEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQ 166 K+K P I E +K + L GDKVT D + ++D Sbjct: 120 KEKITKEILNGKVPVLFNMICESLKGSTGKLA-----VGDKVTLADLVLIAVIDH 169 >2WDU-A nrPDB Length = 211 Score = 50.8 bits (120), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 62/207 (29%), Positives = 90/207 (43%), Gaps = 22/207 (10%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKL-GLDFPNLPYL 63 L Y+ RG PIRLLL +E+ ++ M QW K L G P L Sbjct: 8 LWYFQFRGRAEPIRLLLTCAGVKFEDYQFTM--------DQWPTIKPTLPGGRVPLLDVT 59 Query: 64 -IDGS-RKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 DG R+ +S AI R LAR+ + GET+EE + + + D ++ + P E Sbjct: 60 GPDGKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGE 119 Query: 122 KQK--PEFLK-TIPEKMKLYSEFL----GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKC 174 K+ EF + P +KL SE L GK AG+++T D + L P Sbjct: 120 KEAKIKEFKENNGPTLLKLVSESLESSGGKH--VAGNRITLGDLFLFTTLTHVMETVPGF 177 Query: 175 LDA-FPNLKDFLARF-EGLKKISAYMK 199 L+ FP L +F ++S Y+K Sbjct: 178 LEQKFPKLHEFHKSLPTSCSRLSEYLK 204 >1B48-A nrPDB Length = 221 Score = 50.1 bits (118), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 50/209 (23%), Positives = 87/209 (41%), Gaps = 14/209 (6%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y+N RG IR LL +EE+ R Q+ + L F +P + Sbjct: 6 LYYFNGRGRMESIRWLLAAAGVEFEEEFLE-------TREQYEKMQKDGHLLFGQVPLVE 58 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQ 123 IDG +TQ+ AI+ YLA K++L G+ +ER+R D+ + D M + + + EK+ Sbjct: 59 IDGMM-LTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKE 117 Query: 124 KPEFLKTIPEKMKLYSEFLG-----KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAF 178 + L K + + F + G+++++ D + + L F Sbjct: 118 ESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDF 177 Query: 179 PNLKDFLARFEGLKKISAYMKSSRYLSTP 207 P L+ F R + I +++ P Sbjct: 178 PLLQAFKTRISNIPTIKKFLQPGSQRKPP 206 >1GUL-A nrPDB Length = 222 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 47/203 (23%), Positives = 88/203 (43%), Gaps = 18/203 (8%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 L Y N RG +R +L ++E+ + Q + L F +P + Sbjct: 7 LHYPNGRGRMESVRWVLAAAGVEFDEEFLE-------TKEQLYKLQDGNHLLFQQVPMVE 59 Query: 64 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCY-NPDFEK 122 IDG K+ Q+ +I+ Y+A KH+L G+ +ER D+ +D LIM + PD Sbjct: 60 IDGM-KLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPD--D 116 Query: 123 QKPEFL----KTIPEKMKLYSEFL--GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLD 176 Q+ E + K I ++ + L + + G++++ D + + P L Sbjct: 117 QQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILS 176 Query: 177 AFPNLKDFLARFEGLKKISAYMK 199 AFP L+++ + + I +++ Sbjct: 177 AFPFLQEYTVKLSNIPTIKRFLE 199 >6F05-A nrPDB Length = 215 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 30/162 (18%) Query: 57 FPNLPYLIDGSRKITQSNAIMRYLARKHH-----LCGETEEER--------IRADIVENQ 103 F +P ++DG KI +S A+MRY+A K+ L G+T E+R + A Sbjct: 50 FGTVPAVVDGDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPP 109 Query: 104 VMDNRMQLIMLCYN--PDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVT------- 154 +++ + ++ P EK E + + + +Y L K + AGD V+ Sbjct: 110 LLNLTLHIMFASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAHL 169 Query: 155 -YVDFLAYDILDQYHIFEPKCLDAF-------PNLKDFLARF 188 + D+L I Y I + K + A+ P K+ +A++ Sbjct: 170 PFTDYLVGPIGKAYMIKDRKHVSAWWDDISSRPAWKETVAKY 211 >5F07-A nrPDB Length = 213 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 21/137 (15%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH-----HLCGETEEER 94 D D + +F L F +P + DG K+ +S AI+RY A K+ +L G T EE+ Sbjct: 33 DLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEK 92 Query: 95 --------IRADIVENQVMDNRMQLIMLCYNPDFEKQK-PEFLKTIPEKMK----LYSEF 141 I A + V + Q+++L P +Q E ++T EK++ +Y + Sbjct: 93 ALVDQWLEIEAHNFNDLVFNIVFQVVIL---PRIGQQGDSELVRTYEEKLEKVLDVYEKR 149 Query: 142 LGKRPWFAGDKVTYVDF 158 L K + AGD T D Sbjct: 150 LSKSKYLAGDSFTLADL 166 >4MPF-A nrPDB Length = 266 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 15/147 (10%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKH----HLCGETEEERIR--------ADIVENQV-M 105 LP L DG +T+S+AI+ YL+ K+ H + R R AD + + Sbjct: 75 KLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGI 134 Query: 106 DNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSE--FLGKRPWFAGDKVTYVDFLAYDI 163 +Q++ K+K E +T ++ + E FLG RP+ AG +VT D +A + Sbjct: 135 PLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEE 194 Query: 164 LDQYHIFEPKCLDAFPNLKDFLARFEG 190 L Q + + P L + R E Sbjct: 195 LMQPVALGYELFEGRPRLAAWRGRVEA 221 >4MDC-A nrPDB Length = 252 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 9/74 (12%) Query: 93 ERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPE--FLKT----IPEKMKLYSEFLGKRP 146 +++ AD+ V R ++ L PD P+ L+T I + MK S G RP Sbjct: 126 QKMEADVTRPLV---RERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRP 182 Query: 147 WFAGDKVTYVDFLA 160 W AGD+++Y D A Sbjct: 183 WLAGDRISYGDLAA 196 >2HNL-A nrPDB Length = 225 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 45/204 (22%), Positives = 84/204 (41%), Gaps = 24/204 (11%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L Y+N RG IRLL + SYE+ R R +W + K F ++P L Sbjct: 30 LTYFNGRGRAEVIRLLFALANVSYEDNRIT--------RDEW--KYLKPRTPFGHVPMLN 79 Query: 65 DGSRKITQSNAI--MRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + +S+AI + + EE +I A ++ +D Q ++ + Sbjct: 80 VSGNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLN---IDELFQKLIPWTHEKNTT 136 Query: 123 QKPEFLKTIPEK-----MKLYSEFLGKRPW--FAGDKVTYVDFLAYDILDQYHIFEPKCL 175 +K E + + E + Y +FL + G+KV+ D +++L + + L Sbjct: 137 KKAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNML--MTLDDEVKL 194 Query: 176 DAFPNLKDFLARFEGLKKISAYMK 199 + +P L F+ + + I ++K Sbjct: 195 EEYPQLASFVNKIGQMPGIKEWIK 218 >5ZWP-A nrPDB Length = 208 Score = 35.4 bits (80), Expect = 0.020, Method: Compositional matrix adjust. Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 12/142 (8%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNP 118 +P L+DG + +S AIM YL K+ + + V NQ + M + + Sbjct: 51 TIPTLVDGDFALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFAD 110 Query: 119 DFEKQ-------KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFE 171 + Q PE K I + FL + AGD +T D +L FE Sbjct: 111 YYYPQIFAKAPADPELFKKIETAFDFLNTFLKGHEYAAGDSLTVADLA---LLASVSTFE 167 Query: 172 PKCLDA--FPNLKDFLARFEGL 191 D +PN+ + A + + Sbjct: 168 VASFDISKYPNVAKWYANLKTV 189 >1VF1-A nrPDB Length = 229 Score = 35.4 bits (80), Expect = 0.021, Method: Compositional matrix adjust. Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 9/97 (9%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 +L Y+N RG IR LL +EE R Q+ L F +P + Sbjct: 6 VLYYFNGRGKMESIRWLLAAAGVEFEEVFLE-------TREQYEKLLQSGILMFQQVPMV 58 Query: 64 -IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADI 99 IDG K+ Q+ AI+ Y+A K++L G+ +ER D+ Sbjct: 59 EIDGM-KLVQTRAILNYIAGKYNLYGKDLKERALIDM 94 >5F0G-A nrPDB Length = 215 Score = 34.3 bits (77), Expect = 0.044, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 15/124 (12%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLC--- 115 +P L+D I +S AI YL K+ ++ + D + V++ R+ M Sbjct: 51 TIPTLVDNGFSIWESRAIAVYLVEKYG----KDDYLLPNDPKKRAVINQRLYFDMGTLYE 106 Query: 116 -----YNPDFEKQKP---EFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQY 167 Y P F KP E LK I FL + + AGD++T D + + Sbjct: 107 SFAKYYYPLFRTGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTF 166 Query: 168 HIFE 171 + E Sbjct: 167 EVSE 170 >5J5N-A nrPDB Length = 231 Score = 33.9 bits (76), Expect = 0.060, Method: Compositional matrix adjust. Identities = 30/133 (22%), Positives = 58/133 (43%), Gaps = 23/133 (17%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHHLCG--------ETEEERIRADIVENQVMDNRMQ 110 +P L+ + + +S I++Y+ + + R AD V+ ++ D + Sbjct: 65 QIPVLVHNGKPVCESLIIVQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRK 124 Query: 111 LIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVD---------FLAY 161 I + E K +F+ + +KL LG +P+F G+ + YVD F AY Sbjct: 125 -IWTKKGEEQEAAKKDFI----DSLKLMEGELGDKPYFGGETIGYVDIALVPFYSWFYAY 179 Query: 162 DILDQYHIFEPKC 174 + + ++I E +C Sbjct: 180 ETIGNFNI-EAEC 191 >5ECL-B nrPDB Length = 223 Score = 33.5 bits (75), Expect = 0.077, Method: Compositional matrix adjust. Identities = 40/187 (21%), Positives = 81/187 (43%), Gaps = 33/187 (17%) Query: 1 MPMILGYW-NVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPN 59 +P++L YW ++ G+ + L + + Y E+ ++ +P +S +++K Sbjct: 10 LPILLDYWPSMFGMRARVALREKGVEFEYREEDFS-NKSPLLLQSNPIHKK--------- 59 Query: 60 LPYLIDGSRKITQSNAIMRYL----ARKHHLCGET----EEERIRADIVENQVMDNRMQL 111 +P L+ + + +S +++Y+ K+ + R AD V+ + D + + Sbjct: 60 IPVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFK- 118 Query: 112 IMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVD---------FLAYD 162 + + E K EF+ E +K+ LG +P+F GD YVD F AY+ Sbjct: 119 VWGKKGEEQEAGKKEFI----EAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYE 174 Query: 163 ILDQYHI 169 + I Sbjct: 175 KFGNFSI 181 >5GJQ-x nrPDB Length = 494 Score = 32.3 bits (72), Expect = 0.16, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 22/36 (61%) Query: 173 KCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 +C+ + P LKD L R+ G + S M S++Y++ + Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAAL 156 >2AYN-A nrPDB Length = 404 Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 22/36 (61%) Query: 173 KCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 +C+ + P LKD L R+ G + S M S++Y++ + Sbjct: 31 QCIRSVPELKDALKRYAGALRASGEMASAQYITAAL 66 >4CHS-A nrPDB Length = 219 Score = 32.3 bits (72), Expect = 0.18, Method: Compositional matrix adjust. Identities = 30/120 (25%), Positives = 53/120 (44%), Gaps = 13/120 (10%) Query: 60 LPYLIDGSRKITQSNAIMRYLA-----RKHHLCG---ETEEERIRADIVENQVMDNRMQL 111 +P LI + I++S ++Y+ R L + + R AD V+ ++ D + Sbjct: 54 IPVLIHNGKPISESLIAVQYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKK- 112 Query: 112 IMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFE 171 I + E K EF+ E +KL E LG + +F GD + +VD + ++E Sbjct: 113 IWTSKGEEKEAAKKEFI----EALKLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKVYE 168 >4PNG-A nrPDB Length = 229 Score = 32.0 bits (71), Expect = 0.24, Method: Compositional matrix adjust. Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 17/146 (11%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQL--IMLCY 116 +P L D I S+AI+ YL K+ G+T+ + D+++ V+D R+ ++ Sbjct: 60 TVPTLEDDGHYIWDSHAIIAYLVSKY---GKTDSLYPK-DLLQRAVVDQRLHFESGVIFA 115 Query: 117 NPDFEKQKPEFLK-----------TIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILD 165 N KP F I E +FL + AG+++T DF + Sbjct: 116 NALRSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVS 175 Query: 166 QYHIFEPKCLDAFPNLKDFLARFEGL 191 +F +P + + R + L Sbjct: 176 SLEVFVKVDTTKYPRIAAWFKRLQKL 201 >1AXD-A nrPDB Length = 209 Score = 32.0 bits (71), Expect = 0.24, Method: Compositional matrix adjust. Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 19/160 (11%) Query: 57 FPNLPYLIDGSRKITQSNAIMRYLARKH--HLCGETE-EERIRADI---VE--------N 102 F +P L DG + +S AI +Y ARK+ L E EE D+ VE N Sbjct: 51 FGQVPALQDGDLYLFESRAICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALN 110 Query: 103 QVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYD 162 ++ + ML D +K E L+ + + +++Y L K + AGD ++ D Sbjct: 111 PILFQVLISPMLGGTTD-QKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVS 169 Query: 163 I-LDQYHIFEPKCLDAFPNLKDF---LARFEGLKKISAYM 198 + L + LDA+P++K + L ++K++A M Sbjct: 170 VTLCLFATPYASVLDAYPHVKAWWSGLMERPSVQKVAALM 209 >3VWX-A nrPDB Length = 222 Score = 31.6 bits (70), Expect = 0.31, Method: Compositional matrix adjust. Identities = 41/173 (23%), Positives = 63/173 (36%), Gaps = 28/173 (16%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQL------- 111 +P L + I S+AIM YL K+ ++ D+++ V+D RM Sbjct: 54 TVPTLEEDGHLIWDSHAIMAYLVSKY----GKDDSLYPKDLLKRAVVDQRMYFEAGVLFQ 109 Query: 112 --IMLCYNPDF---EKQKPEF-LKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILD 165 + P F + Q P+ + +I E FL + AGD +T DF + Sbjct: 110 GGLRNITAPLFFRNQTQIPQHQIDSIVESYGFLESFLKNNKYMAGDHLTIADFSIVTSVT 169 Query: 166 QYHIFEPKCLDAFPNLKDFL-----------ARFEGLKKISAYMKSSRYLSTP 207 F FP L +L A G K++ A +KS P Sbjct: 170 SLVAFAEIDQSKFPKLSAWLKSLQSLPFYEEANGAGAKQLVAMVKSKNLTIVP 222 >2VO4-A nrPDB Length = 219 Score = 31.2 bits (69), Expect = 0.39, Method: Compositional matrix adjust. Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 23/132 (17%) Query: 60 LPYLIDGSRKITQSNAIMRYLA-----RKHHLCG---ETEEERIRADIVENQVMDNRMQL 111 +P LI + I +S ++Y+ R L + + R AD V+ ++ D + Sbjct: 54 IPVLIHNGKPICESLIAVQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRK- 112 Query: 112 IMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVD---------FLAYD 162 I + E K EF+ E +KL E LG + +F GD + +VD F AY+ Sbjct: 113 IWTSKGEEKEAAKKEFI----EALKLLEEQLGDKTYFGGDNLGFVDIALVPFYTWFKAYE 168 Query: 163 ILDQYHIFEPKC 174 +I E +C Sbjct: 169 TFGTLNI-ESEC 179 >1PN9-A nrPDB Length = 209 Score = 30.0 bits (66), Expect = 0.80, Method: Compositional matrix adjust. Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 24/143 (16%) Query: 60 LPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLC---- 115 +P L+D + +S AI YLA K+ +++ D + V++ R+ M Sbjct: 52 IPTLVDNGFALWESRAIQIYLAEKYG----KDDKLYPKDPQKRAVVNQRLYFDMGTLYQR 107 Query: 116 -----YNPDFEKQ--KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYH 168 Y F KQ PE K + + + + FL + + AG+ +T D + Y Sbjct: 108 FADYHYPQIFAKQPANPENEKKMKDAVGFLNTFLEGQEYAAGNDLTIADLSLAATIATYE 167 Query: 169 I----FEPKCLDAFPNLKDFLAR 187 + F P +PN+ + AR Sbjct: 168 VAGFDFAP-----YPNVAAWFAR 185 >2C3Q-A nrPDB Length = 247 Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKHHL 86 D + Q L++ F +P L DG +T+S AI+ YL RK+ + Sbjct: 41 DLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKV 87 >1AW9-A nrPDB Length = 216 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/119 (22%), Positives = 47/119 (39%), Gaps = 22/119 (18%) Query: 57 FPNLPYLIDGSRKITQSNAIMRYLARKHHLCG--------ETEEERIRADIVENQVMDNR 108 F +P L+DG + +S AI RY+A K+ G + + ++ + N Sbjct: 51 FGQIPALVDGDEVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNA 110 Query: 109 MQLI-------MLCYNPD---FEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVD 157 L+ +L PD +K + K + +Y L + + AGD+ T D Sbjct: 111 SPLVFQLLVRPLLGGAPDAAVVDKHAEQLAKV----LDVYEAHLARNKYLAGDEFTLAD 165 >1JLV-A nrPDB Length = 209 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 7/117 (5%) Query: 60 LPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQV----MDNRMQLIMLC 115 +P L+D + +S AI YLA K+ + + + V NQ M Q Sbjct: 52 IPTLVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADY 111 Query: 116 YNPDFEKQKP---EFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHI 169 Y P ++P E K + + + + FL + AGD +T D + Y + Sbjct: 112 YYPQIFAKQPANAENEKKMKDAVDFLNTFLDGHKYVAGDSLTIADLTVLATVSTYDV 168 >3MAK-A nrPDB Length = 209 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 29/118 (24%), Positives = 44/118 (37%), Gaps = 7/118 (5%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQV----MDNRMQLIML 114 +P L+D + +S AI YL K+ + + V NQ M Q Sbjct: 52 TIPTLVDNGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFAN 111 Query: 115 CYNPD-FEKQ--KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHI 169 Y P F K PE K I + + FL + + AGD +T D + + + Sbjct: 112 YYYPQVFAKAPADPEAFKKIEAAFEFLNTFLEGQDYAAGDSLTVADIALVATVSTFEV 169 >1GPI-A nrPDB Length = 431 Score = 28.9 bits (63), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 7 YWNVRGLTHP-IRLLLEY-TDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 Y G+T L L++ T S+ + Y M D Y + LN++F +D NLP + Sbjct: 78 YSGTYGITSTGTALTLKFVTGSNVGSRVYLMADDTHYQLLKLLNQEFTFDVDMSNLPCGL 137 Query: 65 DGS 67 +G+ Sbjct: 138 NGA 140 >4S35-A nrPDB Length = 195 Score = 28.5 bits (62), Expect = 2.2, Method: Compositional matrix adjust. Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 30/133 (22%) Query: 64 IDGSRKITQSNAIMRYLARKHHLC------GETEEERIRADIVENQVMDNRMQLIMLCYN 117 IDGS K TQ+ + YL +K + G T+ + +I+ + +D R +L++ Sbjct: 8 IDGSGKTTQAKKLYEYLKQKGYFVSLYREPGGTKVGEVLREILLTEELDERTELLL---- 63 Query: 118 PDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVD-FLAYDILDQYHIFEPKCLD 176 FE + K I EK+ P DKV +D F+ I Q + K LD Sbjct: 64 --FEASRS---KLIEEKII---------PDLKRDKVVILDRFVLSTIAYQGY---GKGLD 106 Query: 177 A--FPNLKDFLAR 187 NL +F R Sbjct: 107 VEFIKNLNEFATR 119 >3LFL-A nrPDB Length = 240 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 14/60 (23%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 144 KRPWFAGDKVTYVDFLAYDILDQYHIFE-PKCLDAFPNLKDFLARFEGLKKISAYMKSSR 202 K +F G+ ++ +D+L + ++ + +C+D P LK ++A + +SA + S + Sbjct: 160 KTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEK 219 >4HQS-A nrPDB Length = 190 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 36 GDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRY 79 G+ + D W GLD+ NLP L+D S K+ ++ + Y Sbjct: 119 GEQSEADFKNWYK-----GLDYKNLPVLVDPSGKLLETYGVRSY 157 >4EVM-A nrPDB Length = 138 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 54 GLDFPNLPYLIDGSRKITQSNAIMRY 79 GLD+ NLP L+D S K+ ++ + Y Sbjct: 80 GLDYKNLPVLVDPSGKLLETYGVRSY 105 >5WZE-A nrPDB Length = 452 Score = 28.1 bits (61), Expect = 2.8, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 15/73 (20%) Query: 20 LLEYTDSSYEEKRYAMGDAPDYDRS--QWLN---EKFKLGLDFPN----LPYLIDGSRKI 70 L+E D Y YA+G PD+DR W+N K + G PN L +L+ R Sbjct: 120 LIEGRDRVY----YALGANPDFDRRLMDWINVIRSKARQGAQPPNEFVALDHLLHDQRLY 175 Query: 71 TQSNA--IMRYLA 81 +N +MRY A Sbjct: 176 KSANEVKVMRYAA 188 >2QB5-A nrPDB Length = 347 Score = 27.7 bits (60), Expect = 3.9, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 3/40 (7%) Query: 171 EPKCLDAFPNLKDFLAR---FEGLKKISAYMKSSRYLSTP 207 E LD P ++ L R +E ++KI AYM+ R S P Sbjct: 102 ETIVLDPLPAIRTLLDRSKSYELIRKIEAYMEDDRICSPP 141 >3E9K-A nrPDB Length = 465 Score = 26.9 bits (58), Expect = 6.5, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 19/36 (52%), Gaps = 7/36 (19%) Query: 124 KPEFLKTIPE-------KMKLYSEFLGKRPWFAGDK 152 +P+ +KT E K+ Y +GKRPW GD+ Sbjct: 79 QPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDE 114 >4MTN-A nrPDB Length = 407 Score = 26.9 bits (58), Expect = 6.6, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 10/78 (12%) Query: 70 ITQSNAIMRYLARKHHLCGETEE--ERIRADIVENQVMDNRMQLIMLCYNPDF-----EK 122 I ++ AI L R + GE+ ERIRA ++E + M R+++++ +PDF E Sbjct: 129 IGKAEAI---LPRSEMIPGESHRPNERIRAVVLEVKKMGPRVRVVLSRAHPDFVRRLLEL 185 Query: 123 QKPEFLKTIPEKMKLYSE 140 + PE + I E L E Sbjct: 186 EIPEVNERIIEIRSLARE 203 >1V2A-A nrPDB Length = 210 Score = 26.6 bits (57), Expect = 8.9, Method: Compositional matrix adjust. Identities = 26/138 (18%), Positives = 62/138 (44%), Gaps = 7/138 (5%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHHLCGET--EEERIRADIVENQVMD--NRMQLIML 114 +P L+D + +S AI+ YL + ++ ++R+ + + D + I+ Sbjct: 50 TIPTLVDNGHVVWESYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIID 109 Query: 115 CYNPDFEKQKP--EFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEP 172 + +K++P E ++ + + L +F+ +R + A D +T D + + + Sbjct: 110 VIHLVMKKEQPSDEQMEKLKGALDLLEQFVTERAYAAADHLTVADICLLGTVTALNWLKH 169 Query: 173 KCLDAFPNLKDFLARFEG 190 L+ FP+++ +L R Sbjct: 170 D-LEPFPHIRAWLERVRA 186 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1XWK-A nrPDB 317 2e-87 5FWG-A nrPDB 315 1e-86 2DC5-A nrPDB 314 2e-86 1B4P-A nrPDB 310 3e-85 4GTU-A nrPDB 309 5e-85 1HNA-A nrPDB 307 2e-84 3GTU-B nrPDB 304 2e-83 1GSU-A nrPDB 279 4e-76 2FHE-A nrPDB 267 3e-72 5AN1-A nrPDB 263 3e-71 2WRT-A nrPDB 254 2e-68 4Q5Q-A nrPDB 249 9e-67 1FHE-A nrPDB 243 4e-65 2GSR-A nrPDB 239 6e-64 2GLR-A nrPDB 238 2e-63 1B8X-A nrPDB 237 4e-63 1BG5-A nrPDB 235 7e-63 1DUG-A nrPDB 234 3e-62 1F3B-A nrPDB 232 8e-62 18GS-A nrPDB 229 7e-61 5D73-A nrPDB 229 8e-61 2VCV-A nrPDB 224 2e-59 4WR5-A nrPDB 224 2e-59 1PL2-A nrPDB 222 1e-58 2VCT-A nrPDB 221 2e-58 1EV4-A nrPDB 219 1e-57 3I6A-A nrPDB 218 2e-57 5LCZ-A nrPDB 218 2e-57 1TU7-A nrPDB 216 6e-57 1B48-A nrPDB 214 3e-56 3KXO-A nrPDB 204 3e-53 5Y9Z-A nrPDB 196 5e-51 1GUL-A nrPDB 193 6e-50 4Q5R-A nrPDB 186 7e-48 1M0U-A nrPDB 184 2e-47 4Q5F-A nrPDB 184 2e-47 1GSQ-A nrPDB 184 3e-47 2AAW-A nrPDB 182 8e-47 1ZL9-A nrPDB 180 6e-46 2WDU-A nrPDB 173 6e-44 2CA8-A nrPDB 167 3e-42 1U3I-A nrPDB 165 2e-41 1YQ1-A nrPDB 152 9e-38 5F07-A nrPDB 107 3e-24 6F05-A nrPDB 106 5e-24 Sequences not found previously or not previously below threshold: 1VF1-A nrPDB 201 2e-52 2HNL-A nrPDB 120 5e-28 1AXD-A nrPDB 86 1e-17 5F06-A nrPDB 82 2e-16 4RI7-A nrPDB 82 3e-16 5EY6-A nrPDB 81 4e-16 4PNG-A nrPDB 77 7e-15 1AW9-A nrPDB 73 1e-13 4YH2-A nrPDB 71 3e-13 5A5K-A nrPDB 71 3e-13 4MPF-A nrPDB 71 5e-13 5F05-A nrPDB 71 5e-13 3VWX-A nrPDB 69 1e-12 2C3Q-A nrPDB 68 3e-12 3LSZ-A nrPDB 68 3e-12 5ZWP-A nrPDB 66 1e-11 1PN9-A nrPDB 65 2e-11 2GDR-A nrPDB 63 8e-11 2CZ2-A nrPDB 62 2e-10 1F2E-A nrPDB 61 3e-10 1JLV-A nrPDB 61 3e-10 3MAK-A nrPDB 61 4e-10 3UAR-A nrPDB 61 4e-10 3M8N-A nrPDB 61 5e-10 1FW1-A nrPDB 60 6e-10 5F0G-A nrPDB 60 8e-10 2IL3-A nrPDB 60 1e-09 3LFL-A nrPDB 59 2e-09 3IBH-A nrPDB 58 3e-09 4IKH-A nrPDB 58 4e-09 4MDC-A nrPDB 57 7e-09 3M3M-A nrPDB 56 8e-09 3TOT-A nrPDB 56 1e-08 2PMT-A nrPDB 55 2e-08 1V2A-A nrPDB 55 3e-08 3UBL-A nrPDB 55 3e-08 5F8B-A nrPDB 53 8e-08 2PVQ-A nrPDB 52 2e-07 4J2F-A nrPDB 51 3e-07 3GH6-A nrPDB 51 4e-07 1E6B-A nrPDB 50 1e-06 4QQ7-A nrPDB 50 1e-06 5J5N-A nrPDB 48 3e-06 4CHS-A nrPDB 48 4e-06 3PR8-A nrPDB 48 4e-06 4FQU-A nrPDB 47 6e-06 3GX0-A nrPDB 46 1e-05 4IGJ-A nrPDB 45 2e-05 4G0L-A nrPDB 45 2e-05 2VO4-A nrPDB 45 3e-05 4PXO-A nrPDB 45 3e-05 3PPU-A nrPDB 45 3e-05 1N2A-A nrPDB 43 9e-05 5NR1-A nrPDB 43 1e-04 4BVY-B nrPDB 42 2e-04 5ECL-B nrPDB 42 2e-04 6GCB-A nrPDB 42 2e-04 2JL4-A nrPDB 41 4e-04 6GZF-A nrPDB 41 5e-04 6GC9-A nrPDB 40 6e-04 4USS-A nrPDB 40 0.001 3C8E-A nrPDB 39 0.001 4PTS-A nrPDB 38 0.003 6EP7-A nrPDB 38 0.004 3RBT-A nrPDB 38 0.004 5N9U-A nrPDB 37 0.007 5ELG-A nrPDB 36 0.010 5LOL-A nrPDB 36 0.012 3M1G-A nrPDB 35 0.019 3IR4-A nrPDB 33 0.085 6JWK-A nrPDB 33 0.14 5HSX-A nrPDB 32 0.23 1GWC-A nrPDB 32 0.23 5KEU-A nrPDB 31 0.30 2JZR-A nrPDB 31 0.32 2YV7-A nrPDB 31 0.43 3BBY-A nrPDB 30 0.67 4J15-A nrPDB 30 0.80 1XX7-A nrPDB 30 0.83 2RAS-A nrPDB 30 0.88 5E1J-A nrPDB 30 1.0 1G6W-A nrPDB 30 1.1 1QO0-A nrPDB 30 1.1 3NIV-A nrPDB 29 1.5 2IWR-A nrPDB 28 2.4 4K0G-A nrPDB 28 2.5 6AIY-A nrPDB 28 2.6 1XA6-A nrPDB 28 3.0 3FQJ-A nrPDB 28 3.1 2PAR-A nrPDB 28 3.8 2H30-A nrPDB 28 4.1 3CXL-A nrPDB 27 5.0 2QB5-A nrPDB 27 5.4 4XRU-B nrPDB 27 5.7 4CZI-A nrPDB 27 5.7 2OSA-A nrPDB 27 6.8 >1XWK-A nrPDB Length = 218 Score = 317 bits (813), Expect = 2e-87, Method: Composition-based stats. Identities = 173/218 (79%), Positives = 200/218 (91%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPMILGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNL Sbjct: 1 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PYLIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IR DI+ENQ MDN MQL M+CYNP+F Sbjct: 61 PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 EK KP++L+ +PEK+KLYSEFLGKRPWFAG+K+T+VDFL YD+LD + IFEPKCLDAFPN Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 LKDF++RFEGL+KISAYMKSSR+L P+FSK+A W NK Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >5FWG-A nrPDB Length = 217 Score = 315 bits (807), Expect = 1e-86, Method: Composition-based stats. Identities = 217/217 (100%), Positives = 217/217 (100%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 120 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL Sbjct: 121 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 180 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK Sbjct: 181 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >2DC5-A nrPDB Length = 231 Score = 314 bits (804), Expect = 2e-86, Method: Composition-based stats. Identities = 167/217 (76%), Positives = 192/217 (88%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MPM LGYW++RGL H IRL LEYTDSSYEEKRY MGDAPDYD+SQWLNEKFKLGLDFPNL Sbjct: 8 MPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNL 67 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PYLIDGS KITQSNAI+RYL RKH+LCGETEEERIR DI+ENQ+MDNRM L LCYN DF Sbjct: 68 PYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADF 127 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 EK KP +L+ +P M+LYSEFLGKRPWFAGDK+T+VDF+AYD+L++ +FE KCLDAFPN Sbjct: 128 EKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPN 187 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 LKDF+ARFEGLKKIS YMK+SR+L P+F+K+A W + Sbjct: 188 LKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGS 224 >1B4P-A nrPDB Length = 217 Score = 310 bits (795), Expect = 3e-85, Method: Composition-based stats. Identities = 185/217 (85%), Positives = 205/217 (94%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIR D++ENQ MD R+QL M+CY+PDFE Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFE 120 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 ++KPE+L+ +PEKMKLYSEFLGK+PWFAG+K+TYVDFL YD+LDQ+ IFEPKCLDAFPNL Sbjct: 121 RKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNL 180 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 KDF+ARFEGLKKIS YMKS R+LS PIF+K+A W+ K Sbjct: 181 KDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >4GTU-A nrPDB Length = 217 Score = 309 bits (793), Expect = 5e-85, Method: Composition-based stats. Identities = 160/217 (73%), Positives = 190/217 (87%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 M LGYW++RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 SMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YLIDG+ KITQSNAI+ Y+ARKH+LCGETEEE+IR DI+ENQ MD QL +CY+PDFE Sbjct: 61 YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFE 120 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 K KPE+L+ +P M+ +S+FLGKRPWF GDK+T+VDFLAYD+LD + IFEP CLDAFPNL Sbjct: 121 KLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPNL 180 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 KDF++RFEGL+KISAYMKSSR+L P+++++A W NK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >1HNA-A nrPDB Length = 217 Score = 307 bits (787), Expect = 2e-84, Method: Composition-based stats. Identities = 164/217 (75%), Positives = 197/217 (90%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 PM LGYWN+RGL H IRLLLEYTDSSYEEK+Y MGDAPDYDRSQWLNEKFKLGLDFPNLP Sbjct: 1 PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YLIDG+ KITQSNAI+RY+ARKH+LCGE+E+E+IR DI+ENQ MD+RMQL LCY+PDFE Sbjct: 61 YLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFE 120 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 K KPE+L+ +PE +KLYS+FLGK+PWF GDK+T+VDF+AYD+L++ +FEP CLDAFPNL Sbjct: 121 KLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNL 180 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 KDF++RFEGL+KISAYMKSSR+L P+F+K+A + NK Sbjct: 181 KDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >3GTU-B nrPDB Length = 224 Score = 304 bits (778), Expect = 2e-83, Method: Composition-based stats. Identities = 147/217 (67%), Positives = 182/217 (83%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 M+LGYW++RGL H IRLLLE+TD+SYEEKRY G+APDYDRSQWL+ KFKL LDFPNLP Sbjct: 5 SMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLP 64 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 YL+DG KITQSNAI+RY+ARKH++CGETEEE+IR DI+ENQVMD R QLI LCY+ D E Sbjct: 65 YLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHE 124 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 K KP++L+ +P ++K +S FLGK WFAG+K+T+VDFL YDILDQ IF+PKCLD FPNL Sbjct: 125 KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNL 184 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 K F+ RFE L+KI+AY++S ++ PI +K+AQW NK Sbjct: 185 KAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >1GSU-A nrPDB Length = 219 Score = 279 bits (715), Expect = 4e-76, Method: Composition-based stats. Identities = 132/216 (61%), Positives = 165/216 (76%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 + LGYW++RGL H IRLLLEYT++ Y+E+RY G APD+D S W NEK KLGLDFPNLPY Sbjct: 2 VTLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPY 61 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 LIDG K+TQSNAI+RY+ARKH++CGETE E+ R D++EN +MD RM LCY+PDFEK Sbjct: 62 LIDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEK 121 Query: 123 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 KP +L+ +P K++ S FLG R WF GDK+T+VDFLAYD+LDQ +F P C + NL Sbjct: 122 LKPAYLEQLPGKLRQLSRFLGSRSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQGNLS 181 Query: 183 DFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FL RFE L+KISAYM+S R++ PIF A W+NK Sbjct: 182 QFLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >2FHE-A nrPDB Length = 216 Score = 267 bits (683), Expect = 3e-72, Method: Composition-based stats. Identities = 100/216 (46%), Positives = 136/216 (62%), Gaps = 5/216 (2%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW +RGL P+RLLLEY YEE+ Y D +W ++KF+LGLD PNLP Sbjct: 1 PAKLGYWKIRGLQQPVRLLLEYLGEKYEEQIYERDDG-----EKWFSKKFELGLDLPNLP 55 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 Y ID K+TQS AI+RY+A KH + G T EER R ++E +D R + + Y P FE Sbjct: 56 YYIDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFE 115 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 + K +LK +P MK++S+FLGK P+ G V++VDF+ Y+ LD EP CLD FPNL Sbjct: 116 QLKEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNL 175 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 + F++R E L I AYM+S+R++ P+ AQ+ Sbjct: 176 QQFMSRIEALPSIKAYMESNRFIKWPLNGWHAQFGG 211 >5AN1-A nrPDB Length = 219 Score = 263 bits (673), Expect = 3e-71, Method: Composition-based stats. Identities = 118/216 (54%), Positives = 150/216 (69%), Gaps = 2/216 (0%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M +LGYW R L PIRL+L YT + +EEK Y +GDAPDYD+S+WL KFKLGL FPNL Sbjct: 1 MLPVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNL 60 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PY IDG KITQS AIMRYLARKH LCG T EE +R D++E Q+ D + Y + Sbjct: 61 PYYIDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTY--EH 118 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 +QK + ++P K++ YS+FLG RPWFAGDK+TY+DFLAY+I DQ+ + CLD F N Sbjct: 119 YEQKDAYTASLPAKLRQYSDFLGSRPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDGFKN 178 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWS 216 L+ F RFE L+ I YM S ++L PI +K AQ++ Sbjct: 179 LQAFQKRFEDLEAIKKYMASPKFLKKPICNKYAQFT 214 >2WRT-A nrPDB Length = 218 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 103/217 (47%), Positives = 138/217 (63%), Gaps = 5/217 (2%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MP LGYW +RGL P+RLLLEY YEE Y D R +WL +KF +GLD PNL Sbjct: 1 MPAKLGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRDD-----REKWLGDKFNMGLDLPNL 55 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PY ID K+TQS AIMRY+A KH + G T EER R ++E MD RM + +CYNP F Sbjct: 56 PYYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCYNPKF 115 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 E+ K ++LK +P +K++S FLG R + G V++VDF+ Y+ LD P+CL+ FP Sbjct: 116 EEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQCLEDFPK 175 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 LK+F +R E L KI AYM+S +++ P+ S +A + Sbjct: 176 LKEFKSRIEDLPKIKAYMESEKFIKWPLNSWIASFGG 212 >4Q5Q-A nrPDB Length = 219 Score = 249 bits (635), Expect = 9e-67, Method: Composition-based stats. Identities = 96/216 (44%), Positives = 139/216 (64%), Gaps = 2/216 (0%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 ILGYW++RG PIRLLL Y+ + +KRY +G APD+DRS+WLNEKF LGLDFPNLPY Sbjct: 4 PILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPY 63 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 IDG K+TQ+ AI+RYL RK+ L G + E IR + E Q D +I +CY+ + +K Sbjct: 64 YIDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANCDK 123 Query: 123 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 KP++LK++P+ +KL S+F+G+ + AG ++YVDF Y+ L + P+ F NLK Sbjct: 124 LKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVPEVFGQFENLK 183 Query: 183 DFLARFEGLKKISAYMKSSRYL--STPIFSKLAQWS 216 ++ R E L ++S Y+K + + P A ++ Sbjct: 184 RYVERMESLPRVSDYIKKQQPKTFNAPTSKWNASYA 219 >1FHE-A nrPDB Length = 217 Score = 243 bits (621), Expect = 4e-65, Method: Composition-based stats. Identities = 101/215 (46%), Positives = 135/215 (62%), Gaps = 5/215 (2%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P LGYW +RGL P+RL LEY YEE Y D R +W++EKF +GLD PNLP Sbjct: 1 PAKLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDD-----REKWMSEKFNMGLDLPNLP 55 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 Y ID K+TQS AIMRY+A KH + G T EER R ++E MD R+ +CYNP FE Sbjct: 56 YYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNPKFE 115 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 + K E++K +P+ +K++S+FLG R + G V++VDF+ Y+ LD P CLD FP L Sbjct: 116 EVKEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPKL 175 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWS 216 K+F +R E L KI AYM+S R++ P+ A + Sbjct: 176 KEFKSRIEALPKIKAYMESKRFIKWPLNGWAASFG 210 >2GSR-A nrPDB Length = 207 Score = 239 bits (611), Expect = 6e-64, Method: Composition-based stats. Identities = 65/213 (30%), Positives = 106/213 (49%), Gaps = 15/213 (7%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ VRG +R+LL D S++E+ M P K F LP Sbjct: 2 PYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTMETWP----------PLKPSCLFRQLP 51 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 DG + QSNAI+R+L R L G+ ++E D+V + V D R + L Y ++E Sbjct: 52 KFQDGDLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYT-NYE 110 Query: 122 KQKPEFLKTIPEKMKLYSEFL----GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 K +++K +PE +K + L G + + G ++++ D+ D+L + + P CLDA Sbjct: 111 AGKEKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDA 170 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFS 210 FP L ++AR KI A++ S +++ PI Sbjct: 171 FPLLSAYVARLSARPKIKAFLASPEHVNRPING 203 >2GLR-A nrPDB Length = 209 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 61/213 (28%), Positives = 106/213 (49%), Gaps = 13/213 (6%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ VRG +R+LL S++E+ + W+ K + LP Sbjct: 2 PYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTI--------DTWMQGLLKPTCLYGQLP 53 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 DG + QSNAI+R+L R L G+ + E + D+V + V D R + + L Y ++E Sbjct: 54 KFEDGDLTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYT-NYE 112 Query: 122 KQKPEFLKTIPEKMKLYSEFL----GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 K +++K +P +K + L G + + GD++++ D+ D+L + + P CLD Sbjct: 113 NGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDN 172 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFS 210 FP L ++AR KI A++ S +++ PI Sbjct: 173 FPLLSAYVARLSARPKIKAFLSSPEHVNRPING 205 >1B8X-A nrPDB Length = 280 Score = 237 bits (604), Expect = 4e-63, Method: Composition-based stats. Identities = 92/216 (42%), Positives = 131/216 (60%), Gaps = 5/216 (2%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 ILGYW ++GL P RLLLEY + YEE Y + +W N+KF+LGL+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 Y IDG K+TQS AI+RY+A KH++ G +ER ++E V+D R + + Y+ DFE Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 K +FL +PE +K++ + L + + GD VT+ DF+ YD LD +P CLDAFP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 F R E + +I Y+KSS+Y++ P+ A + Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >1BG5-A nrPDB Length = 254 Score = 235 bits (601), Expect = 7e-63, Method: Composition-based stats. Identities = 93/217 (42%), Positives = 132/217 (60%), Gaps = 5/217 (2%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M ILGYW ++GL P RLLLEY + YEE Y + +W N+KF+LGL+FPNL Sbjct: 1 MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNL 55 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 PY IDG K+TQS AI+RY+A KH++ G +ER ++E V+D R + + Y+ DF Sbjct: 56 PYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDF 115 Query: 121 EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPN 180 E K +FL +PE +K++ + L + + GD VT+ DF+ YD LD +P CLDAFP Sbjct: 116 ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPK 175 Query: 181 LKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 L F R E + +I Y+KSS+Y++ P+ A + Sbjct: 176 LVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 212 >1DUG-A nrPDB Length = 234 Score = 234 bits (596), Expect = 3e-62, Method: Composition-based stats. Identities = 92/216 (42%), Positives = 131/216 (60%), Gaps = 5/216 (2%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 ILGYW ++GL P RLLLEY + YEE Y + +W N+KF+LGL+FPNLP Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEG-----DKWRNKKFELGLEFPNLP 55 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 Y IDG K+TQS AI+RY+A KH++ G +ER ++E V+D R + + Y+ DFE Sbjct: 56 YYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 115 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 K +FL +PE +K++ + L + + GD VT+ DF+ YD LD +P CLDAFP L Sbjct: 116 TLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 F R E + +I Y+KSS+Y++ P+ A + Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 211 >1F3B-A nrPDB Length = 222 Score = 232 bits (592), Expect = 8e-62, Method: Composition-based stats. Identities = 52/221 (23%), Positives = 91/221 (41%), Gaps = 12/221 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 +L Y+N RG IR LL +EEK K L F +P Sbjct: 4 PVLHYFNARGRMECIRWLLAAAGVEFEEKFIQ-------SPEDLEKLKKDGNLMFDQVPM 56 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ AI+ Y+A K+ L G+ +ER D+ ++D + L P ++ Sbjct: 57 VEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQR 116 Query: 123 QKPEFL---KTIPEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 + L +T + + + L + + G+++T VD ++L F+ L Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTP 176 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP LK F +R L + +++ P+ +K Q + K Sbjct: 177 FPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARK 217 >18GS-A nrPDB Length = 210 Score = 229 bits (584), Expect = 7e-61, Method: Composition-based stats. Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 13/213 (6%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P + Y+ VRG +R+LL S++E+ + W K + LP Sbjct: 3 PYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLP 54 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 DG + QSN I+R+L R L G+ ++E D+V + V D R + I L Y ++E Sbjct: 55 KFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYE 113 Query: 122 KQKPEFLKTIPEKMKLYSEFL----GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 K +++K +P ++K + L G + + GD++++ D+ D+L + + P CLDA Sbjct: 114 AGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDA 173 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFS 210 FP L ++ R K+ A++ S Y++ PI Sbjct: 174 FPLLSAYVGRLSARPKLKAFLASPEYVNLPING 206 >5D73-A nrPDB Length = 208 Score = 229 bits (584), Expect = 8e-61, Method: Composition-based stats. Identities = 66/215 (30%), Positives = 101/215 (46%), Gaps = 16/215 (7%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+ +RGL PIRL+L + + R D P K F L Sbjct: 1 MSYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWPS----------MKSHFHFGQL 50 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 P L DG +I QS AI+R+LARKH+L G E E D+ V D + + Y + Sbjct: 51 PCLYDGDHQIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQA-Y 109 Query: 121 EKQKPEFLKT-IPEKMKLYSEFLG----KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 + +K ++K +P ++ + + L + + G+K++YVDF+ ++ LD + I +P CL Sbjct: 110 DTEKDSYIKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCL 169 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFS 210 D FP LK + R E + Y K P+ Sbjct: 170 DKFPLLKAYHQRMEDRPGLKEYCKQRNRAKIPVNG 204 >2VCV-A nrPDB Length = 222 Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats. Identities = 52/221 (23%), Positives = 89/221 (40%), Gaps = 12/221 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+N RG PIR LL +EEK G A D + + L F +P Sbjct: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKFI--GSAEDLGKLRNDG-----SLMFQQVPM 57 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ AI+ Y+A K++L G+ +ER D+ + D +++L EK Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEK 117 Query: 123 QKPEFL---KTIPEKMKLYSEFL--GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 L KT + + L + + G+K++ D ++L + + Sbjct: 118 DAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISN 177 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP LK R L + +++ P +K + + K Sbjct: 178 FPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 >4WR5-A nrPDB Length = 244 Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats. Identities = 89/216 (41%), Positives = 127/216 (58%), Gaps = 5/216 (2%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 ILGYW ++GL P RLLLE + YEE + +W N+KF+LGL+FPNLP Sbjct: 26 SPILGYWKIKGLVQPTRLLLEXLEEKYEEHLXERDEG-----DKWRNKKFELGLEFPNLP 80 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 Y IDG K+TQS AI+R +A KH++ G +ER ++E V+D R + + Y+ DFE Sbjct: 81 YXIDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFE 140 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNL 181 K +FL +PE +K++ + L + GD VT+ DF+ YD LD +P CLDAFP L Sbjct: 141 TLKVDFLSKLPEMLKMFEDRLCHKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAFPKL 200 Query: 182 KDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSN 217 F R E + +I Y+KSS+Y++ P+ A + Sbjct: 201 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGG 236 >1PL2-A nrPDB Length = 222 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 49/221 (22%), Positives = 88/221 (39%), Gaps = 12/221 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+N RG R LL +EEK + D + N+ + L F +P Sbjct: 5 PKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAE----DLDKLRNDGY---LMFQQVPM 57 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q AI+ Y+A K++L G+ +ER D+ + D +++L P EK Sbjct: 58 VEIDGMKLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEK 117 Query: 123 QKPEFL---KTIPEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 L K + + L + + G+K++ D ++L + + + Sbjct: 118 DAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP LK R L + +++ P+ K + + K Sbjct: 178 FPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARK 218 >2VCT-A nrPDB Length = 222 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 49/221 (22%), Positives = 91/221 (41%), Gaps = 12/221 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y N+RG IR LL +EEK + D + N+ + L F +P Sbjct: 5 PKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAE----DLDKLRNDGY---LMFQQVPM 57 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ AI+ Y+A K++L G+ +E+ D+ + D +++L + E+ Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQ 117 Query: 123 QKPEFL---KTIPEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 L KT + + L + + G+K++ D ++L + + + Sbjct: 118 DAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP LK R L + +++ P+ K + S K Sbjct: 178 FPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRK 218 >1EV4-A nrPDB Length = 221 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 52/221 (23%), Positives = 93/221 (42%), Gaps = 12/221 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 +L Y+N RG IR LL ++EK K L F +P Sbjct: 4 PVLHYFNARGRMECIRFLLAAAGVEFDEKFIQ-------SPEDLEKLKKDGNLMFDQVPM 56 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ AI+ Y+A K+ L G+ +ER D+ ++D ++ L P +K Sbjct: 57 VEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQK 116 Query: 123 QKPEFL---KTIPEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 + L +T + + + L + + G+K+T VD ++L F+ L + Sbjct: 117 EAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFDASLLTS 176 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP LK F +R L + +++ P+ +K + + K Sbjct: 177 FPLLKAFKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARK 217 >3I6A-A nrPDB Length = 222 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 12/213 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+N RG R LL +EEK + D + N+ + L F +P Sbjct: 5 PKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAE----DLDKLRNDGY---LMFQQVPM 57 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ AI+ Y+A K++L G+ +ER D+ + D +IML + P EK Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEK 117 Query: 123 QKPEFL---KTIPEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 L K + + L + + G+K++ D ++L + + + Sbjct: 118 DAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISS 177 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFS 210 FP LK R L + +++ P Sbjct: 178 FPLLKALKTRISNLPTVKKFLQPGSPRKPPPDE 210 >5LCZ-A nrPDB Length = 222 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 51/221 (23%), Positives = 96/221 (43%), Gaps = 12/221 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+N RG R LL +EEK + D + N+ + L F +P Sbjct: 5 PKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAE----DLDKLRNDGY---LMFQQVPM 57 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ AI+ Y+A K++L G+ +ER D+ ++D +I L P ++ Sbjct: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQR 117 Query: 123 QKPEFL---KTIPEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 + L +T + + + L + + G+++T VD ++L F+ L + Sbjct: 118 EAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLLTS 177 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP LK F +R L + +++ + +K + + K Sbjct: 178 FPLLKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARK 218 >1TU7-A nrPDB Length = 208 Score = 216 bits (550), Expect = 6e-57, Method: Composition-based stats. Identities = 68/215 (31%), Positives = 104/215 (48%), Gaps = 16/215 (7%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M L Y+++RGL PIRL L D + + R A D K F L Sbjct: 1 MSYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRIAKDDFSS----------IKSQFQFGQL 50 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF 120 P L DG ++I QS AI+R+LARK++L GE E E D+ V D ++ + Y + Sbjct: 51 PCLYDGDQQIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMA-Y 109 Query: 121 EKQKPEFLKT-IPEKMKLYSEFLG----KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 E +K ++K+ +P ++ + + L R GDK++Y D+ ++ LD + I +P CL Sbjct: 110 ETEKDPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCL 169 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFS 210 D FP LK F R + K+ Y + P+ Sbjct: 170 DKFPLLKVFHQRMKDRPKLKEYCEKRDAAKVPVNG 204 >1B48-A nrPDB Length = 221 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 46/217 (21%), Positives = 86/217 (39%), Gaps = 12/217 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+N RG IR LL +EE+ R Q+ + L F +P Sbjct: 4 PKLYYFNGRGRMESIRWLLAAAGVEFEEEFLE-------TREQYEKMQKDGHLLFGQVPL 56 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + +TQ+ AI+ YLA K++L G+ +ER+R D+ + D M + + + EK Sbjct: 57 VEIDGMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEK 116 Query: 123 QKPEFL---KTIPEKMKLYSEFLGKRP--WFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 ++ L + ++ + L + G+++++ D + + L Sbjct: 117 EESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSD 176 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQ 214 FP L+ F R + I +++ P + Sbjct: 177 FPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVE 213 >3KXO-A nrPDB Length = 202 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 57/208 (27%), Positives = 84/208 (40%), Gaps = 13/208 (6%) Query: 1 MP-MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPN 59 MP L Y+N+RG IR + Y D YE+ R D P+ K L F Sbjct: 4 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGK 53 Query: 60 LPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPD 119 +P L + QS AI RYL + L G TE E+ D + + + D D Sbjct: 54 IPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQD 113 Query: 120 FEKQKPEFLKTI--PEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 ++Q L T P M+ +LG R W G+ VT+ DF +F+P LD Sbjct: 114 VKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDN 173 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLS 205 P L + + + ++ ++K Sbjct: 174 HPRLVTLRKKVQAIPAVANWIKRRPQTK 201 >1VF1-A nrPDB Length = 229 Score = 201 bits (511), Expect = 2e-52, Method: Composition-based stats. Identities = 45/221 (20%), Positives = 80/221 (36%), Gaps = 12/221 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 +L Y+N RG IR LL +EE R Q+ L F +P Sbjct: 5 PVLYYFNGRGKMESIRWLLAAAGVEFEEVFLE-------TREQYEKLLQSGILMFQQVPM 57 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ AI+ Y+A K++L G+ +ER D+ D L+ + +K Sbjct: 58 VEIDGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDK 117 Query: 123 QK---PEFLKTIPEKMKLYSEFLG--KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 K K Y + L + + G+++++ D + + + L Sbjct: 118 VKQCAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKSDALSG 177 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 FP L+ F R + I ++ K + + Sbjct: 178 FPLLQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRR 218 >5Y9Z-A nrPDB Length = 199 Score = 196 bits (499), Expect = 5e-51, Method: Composition-based stats. Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 13/208 (6%) Query: 1 MP-MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPN 59 MP L Y+N+RG IR + Y D YE+ R D P K K L F Sbjct: 1 MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWP----------KIKPTLPFGK 50 Query: 60 LPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPD 119 +P L + QS AI RYL + L G+TE E+ + D V + + D N D Sbjct: 51 IPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQD 110 Query: 120 FEKQKPEFL--KTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 +++ L + P +K +LG + WF G+ VT+ DF + +P L Sbjct: 111 LKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGI 170 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLS 205 +P L + + + ISA++ Sbjct: 171 YPRLVSLRNKVQAIPAISAWILKRPQTK 198 >1GUL-A nrPDB Length = 222 Score = 193 bits (490), Expect = 6e-50, Method: Composition-based stats. Identities = 43/213 (20%), Positives = 84/213 (39%), Gaps = 12/213 (5%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y N RG +R +L ++E+ + Q + L F +P Sbjct: 5 PKLHYPNGRGRMESVRWVLAAAGVEFDEEFLE-------TKEQLYKLQDGNHLLFQQVPM 57 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 + K+ Q+ +I+ Y+A KH+L G+ +ER D+ +D LIM + ++ Sbjct: 58 VEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQ 117 Query: 123 QKPEF---LKTIPEKMKLYSEFL--GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDA 177 QK K I ++ + L + + G++++ D + + P L A Sbjct: 118 QKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSA 177 Query: 178 FPNLKDFLARFEGLKKISAYMKSSRYLSTPIFS 210 FP L+++ + + I +++ P Sbjct: 178 FPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDE 210 >4Q5R-A nrPDB Length = 204 Score = 186 bits (472), Expect = 7e-48, Method: Composition-based stats. Identities = 58/206 (28%), Positives = 91/206 (44%), Gaps = 16/206 (7%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 L Y V+ L PIR LL Y + +E+ R+ GD P+ K + F P Sbjct: 4 SYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPN----------LKPSMPFGKTP 53 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF- 120 L ++ QS AI RYL ++ L G+ + E + D++ + + D R + Y+ D Sbjct: 54 VLEIDGKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADEN 113 Query: 121 ---EKQKPEFLKTIPEKMKLYSEFL-GKRPWFAGDKVTYVDFLAYDILDQ-YHIFEPKCL 175 +K P +TIP K + E + + A K+T+ DF ILD H+ + + Sbjct: 114 SKQKKWDPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLV 173 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSS 201 PNLK + GL I A++ Sbjct: 174 ANQPNLKALREKVLGLPAIKAWVAKR 199 >1M0U-A nrPDB Length = 249 Score = 184 bits (468), Expect = 2e-47, Method: Composition-based stats. Identities = 50/206 (24%), Positives = 93/206 (45%), Gaps = 16/206 (7%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 L Y+NV+ L P+R L Y + YE+ R + P K + +P Sbjct: 49 SYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWP----------ALKPTMPMGQMP 98 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 L +++ QS ++ R+LA+ LCG T E ++ DIV + + D R+++ ++ Y P+ E Sbjct: 99 VLEVDGKRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDE 158 Query: 122 KQKPEFLKTIPEKMKLYSEFLG-----KRPWFAGDKVTYVDFLAYDILDQ-YHIFEPKCL 175 ++ + + E + Y E L A K+T+ D I D ++ + L Sbjct: 159 IKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALGKLTWADVYFAGITDYMNYMVKRDLL 218 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSS 201 + +P L+ + L+ I A+++ Sbjct: 219 EPYPALRGVVDAVNALEPIKAWIEKR 244 >4Q5F-A nrPDB Length = 218 Score = 184 bits (468), Expect = 2e-47, Method: Composition-based stats. Identities = 54/212 (25%), Positives = 82/212 (38%), Gaps = 22/212 (10%) Query: 1 MP-MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPN 59 MP L Y+++RGL RL+ +E+ R D P K F Sbjct: 13 MPQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWP----------ALKPKTPFGQ 62 Query: 60 LPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYN-- 117 LP L + QS AI RYL R+ L G+T E + D + +Q D +L C+ Sbjct: 63 LPLLEVDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAEL-RPCFRVL 121 Query: 118 ---PDFEKQKPEFLKTIPE---KMKLYSEFLGKRP--WFAGDKVTYVDFLAYDILDQYHI 169 + +K+K +P + L +FL K + G VT+ D + D L + Sbjct: 122 AGFEEGDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWES 181 Query: 170 FEPKCLDAFPNLKDFLARFEGLKKISAYMKSS 201 P L LK ++ L I ++ Sbjct: 182 LIPDFLSGHLQLKKYIEHVRELPNIKKWIAER 213 >1GSQ-A nrPDB Length = 202 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 47/207 (22%), Positives = 83/207 (40%), Gaps = 20/207 (9%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+ + G R +L + ++ M D P+ + + N +P Sbjct: 3 YTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNA----------MPV 52 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 L K++QS I R+LAR+ L G+T E+ R D + + D ++ + + P+ K Sbjct: 53 LDIDGTKMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAK 112 Query: 123 QKPEFLKTIPEKMKLYSEFL--------GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKC 174 + + + + K + FL G +F G+ +T D Y L+ P+ Sbjct: 113 EAVQ--QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPEL 170 Query: 175 LDAFPNLKDFLARFEGLKKISAYMKSS 201 L P + R KI+AY+K Sbjct: 171 LKDCPKIVALRKRVAECPKIAAYLKKR 197 >2AAW-A nrPDB Length = 222 Score = 182 bits (463), Expect = 8e-47, Method: Composition-based stats. Identities = 59/210 (28%), Positives = 95/210 (45%), Gaps = 17/210 (8%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAM-GDAPDYDRSQWLNEKFKLGLDFPNLP 61 ++L Y++ RG IRL+ Y Y +KR+ + GDA ++ N K + F +P Sbjct: 16 IVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDA----FVEFKNFKKEKDTPFEQVP 71 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFE 121 L G + QS AI+RYL++K+++CGE+E AD++ V D + F+ Sbjct: 72 ILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNN---TNLFK 128 Query: 122 KQKPEFLKTIPEKMKLYSEFLGKRP---------WFAGDKVTYVDFLAYDILDQYHIFEP 172 + + FL K Y E L K+ +F G+ +TY D +++ D P Sbjct: 129 QNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETKYP 188 Query: 173 KCLDAFPNLKDFLARFEGLKKISAYMKSSR 202 L FP LK L I Y+ + + Sbjct: 189 SSLKNFPLLKAHNEFISNLPNIKNYITNRK 218 >1ZL9-A nrPDB Length = 207 Score = 180 bits (456), Expect = 6e-46, Method: Composition-based stats. Identities = 52/212 (24%), Positives = 87/212 (41%), Gaps = 22/212 (10%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 + L Y+N RG R + Y YE+ R + QW K F L Sbjct: 2 VSYKLTYFNGRGAGEVSRQIFAYAGQQYEDNRVT--------QEQWPALKETCAAPFGQL 53 Query: 61 PYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQ-----LIMLC 115 P+L +K+ QS+AI R+LAR+ L G+T E + + + +Q D + ++ Sbjct: 54 PFLEVDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMG 113 Query: 116 YNP-DFEKQKPEFLKTIPEKMKLYS---EFLG--KRPWFAGDKVTYVDFLAYDILDQYHI 169 + P D E K + +P K Y FL + GD +T++D A I Sbjct: 114 FGPGDVETLKKDIF--LPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDL-AIAQHSADLI 170 Query: 170 FEPKCLDAFPNLKDFLARFEGLKKISAYMKSS 201 + FP LK + + + +I ++++ Sbjct: 171 AKGGDFSKFPELKAHAEKIQAIPQIKKWIETR 202 >2WDU-A nrPDB Length = 211 Score = 173 bits (438), Expect = 6e-44, Method: Composition-based stats. Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 22/211 (10%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+ RG PIRLLL +E+ ++ M P K L +P Sbjct: 6 FKLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPT----------IKPTLPGGRVPL 55 Query: 63 L----IDGSRKITQ-SNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYN 117 L DG + Q S AI R LAR+ + GET+EE + + + D ++ + Sbjct: 56 LDVTGPDGKLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRT 115 Query: 118 PDFEKQ---KPEFLKTIPEKMKLYSEFLGKRP--WFAGDKVTYVDFLAYDILDQYHIFEP 172 P EK+ K P +KL SE L AG+++T D + L P Sbjct: 116 PQGEKEAKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVP 175 Query: 173 KCLD-AFPNLKDFLARFE-GLKKISAYMKSS 201 L+ FP L +F ++S Y+K Sbjct: 176 GFLEQKFPKLHEFHKSLPTSCSRLSEYLKKR 206 >2CA8-A nrPDB Length = 211 Score = 167 bits (423), Expect = 3e-42, Method: Composition-based stats. Identities = 55/213 (25%), Positives = 87/213 (40%), Gaps = 32/213 (15%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 + + Y+N RG IR+ L +YE++R + D P K K + LP Sbjct: 6 IKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWP----------KIKPTIPGGRLPA 55 Query: 63 LI----DGSRK-ITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYN 117 + G K + +S AI RY+A+KHH+ G TEEE + + Q D + Sbjct: 56 VKITDNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMK 115 Query: 118 PDFEKQK----------PEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQY 167 P+ EKQK P L I E +K + L GDKVT D + ++D Sbjct: 116 PEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLA-----VGDKVTLADLVLIAVIDHV 170 Query: 168 HIFEPKCLD-AFPNLKDFLAR-FEGLKKISAYM 198 + + L +P + +++ Y+ Sbjct: 171 TDLDKEFLTGKYPEIHKHRENLLASSPRLAKYL 203 >1U3I-A nrPDB Length = 211 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 52/213 (24%), Positives = 84/213 (39%), Gaps = 32/213 (15%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 + + Y++ RG IR+ L YE++R + D P K K + LP Sbjct: 6 IKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWP----------KIKPTIPGGRLPA 55 Query: 63 LID----GSRK-ITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYN 117 + G K + +S AI RY+A+KHH+ GET+EE + + Q D + Sbjct: 56 VKVTDDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMK 115 Query: 118 PDFEKQK----------PEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQY 167 P EK+K P I E +K + L GDKVT D + ++D Sbjct: 116 PQEEKEKITKEILNGKVPVLFNMICESLKGSTGKLA-----VGDKVTLADLVLIAVIDHV 170 Query: 168 HIFEPKCLD-AFPNLKDFLAR-FEGLKKISAYM 198 + L +P + +++ Y+ Sbjct: 171 TDLDKGFLTGKYPEIHKHRENLLASSPRLAKYL 203 >1YQ1-A nrPDB Length = 208 Score = 152 bits (385), Expect = 9e-38, Method: Composition-based stats. Identities = 54/217 (24%), Positives = 82/217 (37%), Gaps = 26/217 (11%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 L Y+ RGL PIRLL +EE R WL+ K LP Sbjct: 3 SYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMNPD-------QTWLD--IKDSTPMKQLP 53 Query: 62 YLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYN---- 117 L ++ QS AI+RYLARK G+T EE D V + D + Sbjct: 54 VLNIDGFELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSG 113 Query: 118 ---PDFEKQKPEFLKTIPEKMKLYSEFLG-----KRPWFAGDKVTYVDFLAYD---ILDQ 166 + EK + EF +P + ++ G + G +T+ D + D L Sbjct: 114 KSAEEVEKFRSEFF--LPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKN 171 Query: 167 YHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRY 203 Y +F+ L++ + + G+K+ A + Y Sbjct: 172 YGLFDESEFTKLAALREKVNSYPGIKEYIAKRPVTEY 208 >2HNL-A nrPDB Length = 225 Score = 120 bits (301), Expect = 5e-28, Method: Composition-based stats. Identities = 45/206 (21%), Positives = 80/206 (38%), Gaps = 20/206 (9%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L Y+N RG IRLL + SYE+ R + K F ++P Sbjct: 28 YTLTYFNGRGRAEVIRLLFALANVSYEDNRITRDEWKY----------LKPRTPFGHVPM 77 Query: 63 LIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEK 122 L + +S+AI L + L G + E + V + + +LI + + K Sbjct: 78 LNVSGNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTK 137 Query: 123 QKPEFLKTIPEK-----MKLYSEFLGKR--PWFAGDKVTYVDFLAYDILDQYHIFEPKCL 175 K E + + E + Y +FL + G+KV+ D +++L + L Sbjct: 138 -KAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLD--DEVKL 194 Query: 176 DAFPNLKDFLARFEGLKKISAYMKSS 201 + +P L F+ + + I ++K Sbjct: 195 EEYPQLASFVNKIGQMPGIKEWIKKR 220 >5F07-A nrPDB Length = 213 Score = 107 bits (268), Expect = 3e-24, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 61/176 (34%), Gaps = 17/176 (9%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH-----HLCGETEEER 94 D D + +F L F +P + DG K+ +S AI+RY A K+ +L G T EE+ Sbjct: 33 DLDSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEK 92 Query: 95 IRAD--------IVENQVMDNRMQLIMLCY--NPDFEKQKPEFLKTIPEKMKLYSEFLGK 144 D + V + Q+++L + + + + + + +Y + L K Sbjct: 93 ALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQGDSELVRTYEEKLEKVLDVYEKRLSK 152 Query: 145 RPWFAGDKVTYVDFLAYDILDQ--YHIFEPKCLDAFPNLKDFLARFEGLKKISAYM 198 + AGD T D + L + M Sbjct: 153 SKYLAGDSFTLADLSHLPATRYLVNEAGLGHLVKDRKKLNAWWEDISSRPAWKKLM 208 >6F05-A nrPDB Length = 215 Score = 106 bits (266), Expect = 5e-24, Method: Composition-based stats. Identities = 44/191 (23%), Positives = 78/191 (40%), Gaps = 31/191 (16%) Query: 30 EKRYAMGDAP-DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH---- 84 EK A P D + + + F +P ++DG KI +S A+MRY+A K+ Sbjct: 22 EKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYVAEKYRSQG 81 Query: 85 -HLCGETEEERIRAD--------IVENQVMDNRMQLIMLCYN--PDFEKQKPEFLKTIPE 133 L G+T E+R + + +++ + ++ P EK E + + Sbjct: 82 PDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIKESEEKLAG 141 Query: 134 KMKLYSEFLGKRPWFAGDKVTYV--------DFLAYDILDQYHIFEPKCLDAF------- 178 + +Y L K + AGD V+ D+L I Y I + K + A+ Sbjct: 142 VLDVYEAHLSKSKYLAGDFVSLADLAHLPFTDYLVGPIGKAYMIKDRKHVSAWWDDISSR 201 Query: 179 PNLKDFLARFE 189 P K+ +A++ Sbjct: 202 PAWKETVAKYS 212 >1AXD-A nrPDB Length = 209 Score = 86.1 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 40/190 (21%), Positives = 67/190 (35%), Gaps = 20/190 (10%) Query: 21 LEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYL 80 LE S YE A + F +P L DG + +S AI +Y Sbjct: 21 LEEAGSDYEIVPINFATAEHKSPEHLVRN------PFGQVPALQDGDLYLFESRAICKYA 74 Query: 81 ARKHH---LCGETEEERIRADIVENQVMDNRMQ-----LIMLCYNP-----DFEKQKPEF 127 ARK+ L EE D+ + L + +P +K E Sbjct: 75 ARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDEN 134 Query: 128 LKTIPEKMKLYSEFLGKRPWFAGDKVTYVDF-LAYDILDQYHIFEPKCLDAFPNLKDFLA 186 L+ + + +++Y L K + AGD ++ D L + LDA+P++K + + Sbjct: 135 LEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLFATPYASVLDAYPHVKAWWS 194 Query: 187 RFEGLKKISA 196 + Sbjct: 195 GLMERPSVQK 204 >5F06-A nrPDB Length = 216 Score = 81.9 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 24/184 (13%), Positives = 52/184 (28%), Gaps = 17/184 (9%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKHHLCG------ETEEE 93 D + F F +P L + + +S AI Y+A K G E +E Sbjct: 33 DLFAGEHKQPPFLAKNPFGQIPALEEDDLTLFESRAITSYIAEKFKGTGYDLIRHENLKE 92 Query: 94 RIRA--------DIVENQVMDNRMQLIMLCY--NPDFEKQKPEFLKTIPEKMKLYSEFLG 143 + Q ++ N + + ++ + + + +Y L Sbjct: 93 AASVKVWTEVESHRYNPAIAPIVFQFMVAPLRGNSPDQTIIDDNVEKLGKVLDIYEAKLS 152 Query: 144 KRPWFAGDKVTYVDFLAYDILDQYHIF-EPKCLDAFPNLKDFLARFEGLKKISAYMKSSR 202 + AGD + D ++ P++K + + Sbjct: 153 STKYLAGDFYSLADLHHLPYTYYLMKTPAASVVNERPHVKAWWEDISSRPAFKKVAEGMN 212 Query: 203 YLST 206 ++ Sbjct: 213 FVKK 216 >4RI7-A nrPDB Length = 215 Score = 81.5 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 49/142 (34%), Gaps = 15/142 (10%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH------HLCGETEEE 93 D + + ++ F +P D S + +S AI RY+ K+ L G Sbjct: 36 DLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILS 95 Query: 94 RIRADIVENQ--------VMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKR 145 + D D L+ P E + + + + + +Y + LG+ Sbjct: 96 KANIDQWVETDGQTFGPPSGDLVHDLLFSSV-PVDEALIKKNVDKLAKVLDIYEQKLGQT 154 Query: 146 PWFAGDKVTYVDFLAYDILDQY 167 + AGD+ ++ D D Sbjct: 155 RFLAGDEFSFADLSHLPNGDYL 176 >5EY6-A nrPDB Length = 217 Score = 81.1 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 61/192 (31%), Gaps = 19/192 (9%) Query: 30 EKRYAMGDAP-DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH---- 84 EK P D + + + F +P D S + +S +I RY+ K+ Sbjct: 24 EKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESISLFESRSICRYVCEKYADRG 83 Query: 85 --HLCGETEEERIRADIVEN----------QVMDNRMQLIMLCYNPDFEKQKPEFLKTIP 132 L G ER D + ++ P + + + + Sbjct: 84 DKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQDQGVIKQNEEKLG 143 Query: 133 EKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIF--EPKCLDAFPNLKDFLARFEG 190 + + +Y + LG+ + AGD+ T+ D D + + N+ + Sbjct: 144 KVLDIYEQRLGESRFLAGDEFTFADLSHLPNGDYLVNATDKGHLFTSRENVGRWWNEISD 203 Query: 191 LKKISAYMKSSR 202 + ++ + Sbjct: 204 RESWKKVIEMRK 215 >4PNG-A nrPDB Length = 229 Score = 76.9 bits (188), Expect = 7e-15, Method: Composition-based stats. Identities = 40/206 (19%), Positives = 70/206 (33%), Gaps = 24/206 (11%) Query: 1 MPMILGY-----WNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGL 55 MP ++ Y VR ++L L + YE ++ +E+F Sbjct: 7 MPKLILYGLEASPPVR----AVKLTLAALEVPYEFVEVNTRAKENF------SEEFLKKN 56 Query: 56 DFPNLPYLIDGSRKITQSNAIMRYLARKHH----LCGETEEERIRADI---VENQV--MD 106 +P L D I S+AI+ YL K+ L + +R D E+ V + Sbjct: 57 PQHTVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFAN 116 Query: 107 NRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQ 166 + + E I E +FL + AG+++T DF + Sbjct: 117 ALRSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSS 176 Query: 167 YHIFEPKCLDAFPNLKDFLARFEGLK 192 +F +P + + R + L Sbjct: 177 LEVFVKVDTTKYPRIAAWFKRLQKLP 202 >1AW9-A nrPDB Length = 216 Score = 72.7 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 30/183 (16%), Positives = 56/183 (30%), Gaps = 15/183 (8%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKHHLCGETE-------- 91 D F F +P L+DG + +S AI RY+A K+ G Sbjct: 34 DLTTGAHKQPDFLALNPFGQIPALVDGDEVLFESRAINRYIASKYASEGTDLLPATASAA 93 Query: 92 ----EERIRADIVENQVMDNRMQLIM--LCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKR 145 + + QL++ L + + + + + +Y L + Sbjct: 94 KLEVWLEVESHHFYPNASPLVFQLLVRPLLGGAPDAAVVDKHAEQLAKVLDVYEAHLARN 153 Query: 146 PWFAGDKVTYVDFLAYDILDQYHIF-EPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYL 204 + AGD+ T D L + + A P++K + + + Sbjct: 154 KYLAGDEFTLADANHASYLLYLSKTPKAGLVAARPHVKAWWEAIVARPAFQKTVAAIPLP 213 Query: 205 STP 207 P Sbjct: 214 PPP 216 >4YH2-A nrPDB Length = 222 Score = 71.5 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 63/186 (33%), Gaps = 15/186 (8%) Query: 16 PIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNA 75 ++L L + +YE D L+ ++ +P L D I S+A Sbjct: 17 AVKLTLAALNLTYEYVNV------DIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHA 70 Query: 76 IMRYLARKHH----LCGETEEERIRADI---VENQV--MDNRMQLIMLCYNPDFEKQKPE 126 I+ YL K+ L + +R D E+ V + + K E Sbjct: 71 IIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKE 130 Query: 127 FLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLA 186 I E FL + + AG+++T DF + F +P + ++ Sbjct: 131 RYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIK 190 Query: 187 RFEGLK 192 + E L Sbjct: 191 KLEQLP 196 >5A5K-A nrPDB Length = 212 Score = 71.5 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 32/192 (16%), Positives = 60/192 (31%), Gaps = 25/192 (13%) Query: 21 LEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYL 80 L + +E + D + E F F +P DG K+ +S AI +Y+ Sbjct: 22 LHEKNLDFELVHVELKDG------EHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYI 75 Query: 81 ARKH-----HLCGETEEE--RIRADIVENQVMD----------NRMQLIMLCYN-PDFEK 122 A ++ +L + + + QV D Q+ Y E Sbjct: 76 AHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEA 135 Query: 123 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYH-IFEPKCLDAFPNL 181 E + + + +Y L + + AG+ T D + K P + Sbjct: 136 VVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRV 195 Query: 182 KDFLARFEGLKK 193 +++A Sbjct: 196 NEWVAEITKRPA 207 >4MPF-A nrPDB Length = 266 Score = 70.7 bits (172), Expect = 5e-13, Method: Composition-based stats. Identities = 41/166 (24%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH----HLCGETEEERI 95 D + Q +++F LP L DG +T+S+AI+ YL+ K+ H + R Sbjct: 56 DLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARA 115 Query: 96 RADIVENQVMD---------NRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLY--SEFLGK 144 R D +Q++ K+K E +T ++ + +FLG Sbjct: 116 RVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGD 175 Query: 145 RPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEG 190 RP+ AG +VT D +A + L Q + + P L + R E Sbjct: 176 RPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEA 221 >5F05-A nrPDB Length = 212 Score = 70.7 bits (172), Expect = 5e-13, Method: Composition-based stats. Identities = 29/181 (16%), Positives = 59/181 (32%), Gaps = 15/181 (8%) Query: 28 YEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKHHLC 87 YE++ + + E F +P +DG K+ +S AI +Y+A ++ Sbjct: 22 YEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQYVAHQYASK 81 Query: 88 GETE------------EERIRADIVENQVMDNR-MQLIMLCYN-PDFEKQKPEFLKTIPE 133 G + + + + Q+ + P E T+ + Sbjct: 82 GTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFKPVFGLPTDAALVAETEVTLGK 141 Query: 134 KMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYH-IFEPKCLDAFPNLKDFLARFEGLK 192 + +Y L + + A D T D + K D+ P++ ++A G Sbjct: 142 VLDVYEARLSQSKYLASDSFTLADLHHLPNIQALLGTPSKKLFDSRPHVSAWVASITGRP 201 Query: 193 K 193 Sbjct: 202 A 202 >3VWX-A nrPDB Length = 222 Score = 69.2 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 37/189 (19%), Positives = 64/189 (33%), Gaps = 18/189 (9%) Query: 16 PIR---LLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQ 72 P+R L L+ + +E K + + L+E++ +P L + I Sbjct: 14 PVRACLLTLKALNLPFEYKVV------NLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWD 67 Query: 73 SNAIMRYLARKHH----LCGETEEERIRAD--IVENQ---VMDNRMQLIMLCYNPDFEKQ 123 S+AIM YL K+ L + +R D + + + + + Sbjct: 68 SHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQI 127 Query: 124 KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKD 183 + +I E FL + AGD +T DF + F FP L Sbjct: 128 PQHQIDSIVESYGFLESFLKNNKYMAGDHLTIADFSIVTSVTSLVAFAEIDQSKFPKLSA 187 Query: 184 FLARFEGLK 192 +L + L Sbjct: 188 WLKSLQSLP 196 >2C3Q-A nrPDB Length = 247 Score = 68.0 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 37/197 (18%), Positives = 72/197 (36%), Gaps = 25/197 (12%) Query: 13 LTHPIRLLLEYT---DSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRK 69 L+ P R + + D +E + D + Q L++ F +P L DG Sbjct: 17 LSQPCRAVYIFAKKNDIPFELRIV------DLIKGQHLSDAFAQVNPLKKVPALKDGDFT 70 Query: 70 ITQSNAIMRYLARKHHL----CGETEEERIRADIVE---------NQVMDNRMQLIMLCY 116 +T+S AI+ YL RK+ + + + R R D + + +++ + Sbjct: 71 LTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVF 130 Query: 117 --NPDFEKQKPEFLKTIPEKMKLYS-EFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPK 173 P + L + ++L +FL + + G ++ D +A L + Sbjct: 131 LGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQ 190 Query: 174 CLDAFPNLKDFLARFEG 190 + P L + R E Sbjct: 191 VFEGRPKLATWRQRVEA 207 >3LSZ-A nrPDB Length = 225 Score = 68.0 bits (165), Expect = 3e-12, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 64/206 (31%), Gaps = 19/206 (9%) Query: 11 RGLTHPIRLLLEYTDSSYEE------KRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 R LL D +E R A P+ + + +P L Sbjct: 10 RSRASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVN-PLGQIPCLE 68 Query: 65 DGSRKITQSNAIMRYLARKHH--LCGETEEERIR--------ADIVENQVMDNRM-QLIM 113 + +T+S AI ++AR L +E E A VE ++ ++ Q Sbjct: 69 EEGLILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQRSG 128 Query: 114 LCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPK 173 +P+ + + + + + G + T D + L P Sbjct: 129 GGTSPEGQAAIAIAAERLRRPLARLERHFAAEDYLVGGRFTVADLNLAETLRYGQAH-PA 187 Query: 174 CLDAFPNLKDFLARFEGLKKISAYMK 199 L+ FP + +L R + M+ Sbjct: 188 LLEPFPAVAAWLDRCQSRPAFRLMME 213 >5ZWP-A nrPDB Length = 208 Score = 66.1 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 34/186 (18%), Positives = 61/186 (32%), Gaps = 16/186 (8%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y + + + +K + + L +F +P Sbjct: 1 MDFYYLPGSAPCRSVLMTAKALGIELNKKLL------NLQAGEHLKPEFLKINPQHTIPT 54 Query: 63 LIDGSRKITQSNAIMRYLARKHH----LCGETEEERIRAD--IVENQVMDNRMQLIMLCY 116 L+DG + +S AIM YL K+ L + ++R + + + + Y Sbjct: 55 LVDGDFALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFD-MGTLYKSFADYYY 113 Query: 117 NPDFEKQ--KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKC 174 F K PE K I + FL + AGD +T D + + + Sbjct: 114 PQIFAKAPADPELFKKIETAFDFLNTFLKGHEYAAGDSLTVADLALLASVSTFEVASFD- 172 Query: 175 LDAFPN 180 + +PN Sbjct: 173 ISKYPN 178 >1PN9-A nrPDB Length = 209 Score = 65.3 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 34/202 (16%), Positives = 67/202 (33%), Gaps = 28/202 (13%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y +++ K D + + + +F +P Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKL------TDLMKGEHMKPEFLKLNPQHCIPT 54 Query: 63 LIDGSRKITQSNAIMRYLARKHH----LCGETEEERIRA------DI--VENQVMDNRM- 109 L+D + +S AI YLA K+ L + ++R D+ + + D Sbjct: 55 LVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYP 114 Query: 110 -QLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYH 168 NP+ EK+ + + + FL + + AG+ +T D + Y Sbjct: 115 QIFAKQPANPENEKKMKDAVG-------FLNTFLEGQEYAAGNDLTIADLSLAATIATYE 167 Query: 169 IFEPKCLDAFPNLKDFLARFEG 190 + +PN+ + AR + Sbjct: 168 VAGFD-FAPYPNVAAWFARCKA 188 >2GDR-A nrPDB Length = 202 Score = 63.4 bits (153), Expect = 8e-11, Method: Composition-based stats. Identities = 35/211 (16%), Positives = 76/211 (36%), Gaps = 17/211 (8%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L Y P + L ++E + + +L +P Sbjct: 1 MKLYYSPGACSLSP-HIALREAGLNFELVQVDLASKKTASGQDYLEVN-----PAGYVPC 54 Query: 63 LI-DGSRKITQSNAIMRYLARKHHLCGETEE------ERIRADIVENQVMDNRMQLIMLC 115 L D R +T+ AI++Y+A + + G+ ER N + + Sbjct: 55 LQLDDGRTLTEGPAIVQYVADQ--VPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPL 112 Query: 116 YNPDFEKQ-KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKC 174 +NP + K +++ ++ + L P+ GD+++ D + +L Sbjct: 113 FNPASSDEWKNAVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYLFVVLGWSAYVNID- 171 Query: 175 LDAFPNLKDFLARFEGLKKISAYMKSSRYLS 205 L +P+L+ F R G + + + +++ + Sbjct: 172 LSPWPSLQAFQGRVGGREAVQSALRAEGLIK 202 >2CZ2-A nrPDB Length = 223 Score = 61.9 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 57/183 (31%), Gaps = 12/183 (6%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 +R+ L YE + D Q E+F+ +P L I QS AI Sbjct: 27 VRIALALKGIDYEIVPINL----IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAI 82 Query: 77 MRYLARKH---HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF--EKQKPEFLKTI 131 M YL L + ++R ++ + + L L E Q K I Sbjct: 83 MEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVI 142 Query: 132 PEKMKLYSEFLGKR--PWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFE 189 + L + GD+V+ D + F+ L +P + Sbjct: 143 TSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-LSPYPTISHINKELL 201 Query: 190 GLK 192 L+ Sbjct: 202 ALE 204 >1F2E-A nrPDB Length = 201 Score = 61.5 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 30/185 (16%), Positives = 63/185 (34%), Gaps = 12/185 (6%) Query: 21 LEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL-IDGSRKITQSNAIMRY 79 L T + +E + + R E F +P L +D +T++ AI+ Y Sbjct: 18 LRETGADFEAVKVDLA-----VRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLY 72 Query: 80 LARKHHLCGETEEE-----RIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEK 134 +A ++ G E + + + L ++ K +++ Sbjct: 73 IADQNPASGLAPAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNH 132 Query: 135 MKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKI 194 + + L R +AG+ + D Y +L + A+P L + + + Sbjct: 133 LAALDKELAGRDHYAGNAFSVADIYLYVMLGWPAYVGID-MAAYPALGAYAGKIAQRPAV 191 Query: 195 SAYMK 199 A +K Sbjct: 192 GAALK 196 >1JLV-A nrPDB Length = 209 Score = 61.1 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 32/197 (16%), Positives = 64/197 (32%), Gaps = 24/197 (12%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y +++ K + + + +F +P Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKL------TNLMAGEHMKPEFLKINPQHCIPT 54 Query: 63 LIDGSRKITQSNAIMRYLARKHH----LCGETEEERIRA------DI--VENQVMDNRMQ 110 L+D + +S AI YLA K+ L + ++R D+ + + D Sbjct: 55 LVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYP 114 Query: 111 LIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIF 170 I + E +K + + + + FL + AGD +T D + Y + Sbjct: 115 QIFAKQPANAENEKK-----MKDAVDFLNTFLDGHKYVAGDSLTIADLTVLATVSTYDV- 168 Query: 171 EPKCLDAFPNLKDFLAR 187 L +P++ + R Sbjct: 169 AGFELAKYPHVAAWYER 185 >3MAK-A nrPDB Length = 209 Score = 61.1 bits (147), Expect = 4e-10, Method: Composition-based stats. Identities = 29/174 (16%), Positives = 57/174 (32%), Gaps = 15/174 (8%) Query: 6 GYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID 65 Y + + + +K + + L +F +P L+D Sbjct: 5 YYLPGSSPCRSVIMTAKAVGVELNKKLL------NLQAGEHLKPEFLKINPQHTIPTLVD 58 Query: 66 GSRKITQSNAIMRYLARKHH----LCGETEEERIRAD--IVENQVMDNRMQLIMLCYNPD 119 + +S AI YL K+ L + ++R + + + + Y Sbjct: 59 NGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFD-MGTLYQSFANYYYPQV 117 Query: 120 FEKQ--KPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFE 171 F K PE K I + + FL + + AGD +T D + + + + Sbjct: 118 FAKAPADPEAFKKIEAAFEFLNTFLEGQDYAAGDSLTVADIALVATVSTFEVAK 171 >3UAR-A nrPDB Length = 227 Score = 61.1 bits (147), Expect = 4e-10, Method: Composition-based stats. Identities = 41/206 (19%), Positives = 74/206 (35%), Gaps = 14/206 (6%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M M L Y+ P ++L +E + +G + +L K + Sbjct: 1 MVMKLYYFPGACSLAP-HIVLREAGLDFELENVDLGTKKTGSGADFLQVNPK-----GYV 54 Query: 61 PYLI-DGSRKITQSNAIMRYLAR---KHHLCGET-EEERIRADIVENQVMDNRMQLIMLC 115 P L D + +T+ I++YLA + L + ER R + + Sbjct: 55 PALQLDDGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPF 114 Query: 116 YNPDF-EKQKPEFLKTIPEKMKLYSEFL-GKRPWFAGDKVTYVDFLAYDILDQYHIFEPK 173 +NP+ E K L + ++ + L PW GD+ + D +L + Sbjct: 115 WNPESPEASKQIALGLLSRRLDYVEDRLEAGGPWLMGDRYSVADAYLSTVLGWCEYLKID 174 Query: 174 CLDAFPNLKDFLARFEGLKKISAYMK 199 L +P + +L R + + A MK Sbjct: 175 -LSKWPRILAYLERNQARPAVQAAMK 199 >3M8N-A nrPDB Length = 225 Score = 60.7 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 41/200 (20%), Positives = 66/200 (33%), Gaps = 17/200 (8%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 L G ++ +RL L D+ Y D R + F +P Sbjct: 4 YKLYSMQRSGNSYKVRLALALLDAPY------RAVEVDILRGESRTPDFLAKNPSGQVPL 57 Query: 63 LIDG-SRKITQSNAIMRYLARKHHLCGETEEERIRAD--IVENQVM---DNRMQLIMLCY 116 L R + +SNAI+ YLA L +T +R A + Q + LC Sbjct: 58 LETAPGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCL 117 Query: 117 NPDFEKQKPEFLKTIPEK----MKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEP 172 + L+ E+ +++ L +FA ++T D Y + Sbjct: 118 VKGGRDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQCDF 177 Query: 173 KCLDAFPNLKDFLARFEGLK 192 L FP + +L R E Sbjct: 178 D-LSTFPAVNAWLRRVEQTP 196 >1FW1-A nrPDB Length = 216 Score = 60.3 bits (145), Expect = 6e-10, Method: Composition-based stats. Identities = 30/184 (16%), Positives = 56/184 (30%), Gaps = 12/184 (6%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 +R+ L Y+ + D Q ++ F+ +P L I QS AI Sbjct: 20 VRIALALKGIDYKTVPINL----IKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAI 75 Query: 77 MRYLARKH---HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPE 133 + YL L + ++R ++ + + L L ++ Sbjct: 76 IEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAI 135 Query: 134 KM--KLYSEFLGKRP--WFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFE 189 + L + GD+VT D + F+ L +P + R Sbjct: 136 TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVD-LTPYPTISSINKRLL 194 Query: 190 GLKK 193 L+ Sbjct: 195 VLEA 198 >5F0G-A nrPDB Length = 215 Score = 59.9 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 59/176 (33%), Gaps = 17/176 (9%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M Y G + ++ + +K + + L +F +P Sbjct: 1 MDFYYMPGGGGCRTVIMVAKALGLELNKKLL------NTMEGEQLKPEFVKLNPQHTIPT 54 Query: 63 LIDGSRKITQSNAIMRYLARKHH----LCGETEEERIRAD--IVENQVMDNRMQLIMLCY 116 L+D I +S AI YL K+ L ++R + + + + Y Sbjct: 55 LVDNGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFD-MGTLYESFAKYYY 113 Query: 117 NPDFEKQKP---EFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHI 169 P F KP E LK I FL + + AGD++T D + + + Sbjct: 114 -PLFRTGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTFEV 168 >2IL3-A nrPDB Length = 221 Score = 59.6 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 37/190 (19%), Positives = 69/190 (36%), Gaps = 21/190 (11%) Query: 14 THPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQS 73 + L + E+K + L +F +P L D IT+S Sbjct: 15 CRAVELTAKALGLELEQKTI------NLLTGDHLKPEFVKLNPQHTIPVLDDNGTIITES 68 Query: 74 NAIMRYLARKHH----LCGETEEERIRADI---VENQVMDNRMQLI--MLCY--NPDFEK 122 +AIM YL K+ L + ++ R + E+ V+ RM+ I + + D + Sbjct: 69 HAIMIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFGKSDIPE 128 Query: 123 QKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 + E+++ +L + L + AG +T DF + P P + Sbjct: 129 DRVEYVQK---SYELLEDTLVD-DFVAGPTMTIADFSCISTISSIMGVVPLEQSKHPRIY 184 Query: 183 DFLARFEGLK 192 ++ R + L Sbjct: 185 AWIDRLKQLP 194 >3LFL-A nrPDB Length = 240 Score = 58.8 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 34/194 (17%), Positives = 73/194 (37%), Gaps = 14/194 (7%) Query: 14 THPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQS 73 RL+L+ +E + + P +W +K F +P L + ++ Sbjct: 35 AERTRLVLKAKGIRHEVININLKNKP-----EWFFKKN----PFGLVPVLENSQGQLIYE 85 Query: 74 NAIMR-YLARKH---HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLK 129 +AI YL + L + E+ ++ + + + E + Sbjct: 86 SAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEE 145 Query: 130 TIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFE-PKCLDAFPNLKDFLARF 188 E KL K +F G+ ++ +D+L + ++ + +C+D P LK ++A Sbjct: 146 FRKEFTKLEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAM 205 Query: 189 EGLKKISAYMKSSR 202 + +SA + S + Sbjct: 206 KEDPTVSALLTSEK 219 >3IBH-A nrPDB Length = 233 Score = 58.0 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 28/179 (15%), Positives = 56/179 (31%), Gaps = 16/179 (8%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLI-DGSRKITQSNAIMRYLARKHH---LCGETEEERI 95 + + + +F +P L D I + AI Y+ L G+T E+ Sbjct: 52 NLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKG 111 Query: 96 RADIVENQVM-------DNRMQLIMLCYNPDFE--KQKPEFLK---TIPEKMKLYSEFLG 143 ++ + P+ E + K L+ M + L Sbjct: 112 VIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLR 171 Query: 144 KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSR 202 +RP+ AGD + D L I + + + L+ + R + + ++ Sbjct: 172 ERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLEIRS 230 >4IKH-A nrPDB Length = 244 Score = 57.6 bits (138), Expect = 4e-09, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 73/202 (36%), Gaps = 25/202 (12%) Query: 20 LLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID----GS--RKITQS 73 +LE YE R + ++ + +F +P ++D G + +S Sbjct: 39 MLEEIGLPYEAHRVS------FETQDQMTPEFLSVSPNNKIPAILDPHGPGDQPLALFES 92 Query: 74 NAIMRYLARKHH--LCGETEEERIRADIVENQVMDNRMQLIMLCYNP-----DFEKQKP- 125 AI+ YLA K L E+ + Q+ + + ++E ++P Sbjct: 93 GAILIYLADKSGQLLAQESAARYETIQWLMFQMGGIGPMFGQVGFFNKFAGREYEDKRPL 152 Query: 126 -EFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPK----CLDAFPN 180 ++ + + + LG R W G++ T D + + F +D FP Sbjct: 153 ERYVNEAKRLLGVLDKHLGGREWIMGERYTIADIATFPWIRNLIGFYEAGELVGIDNFPE 212 Query: 181 LKDFLARFEGLKKISAYMKSSR 202 +K LA+F + ++ + Sbjct: 213 VKRVLAKFVARPAVIRGLEIPK 234 >4MDC-A nrPDB Length = 252 Score = 56.9 bits (136), Expect = 7e-09, Method: Composition-based stats. Identities = 43/235 (18%), Positives = 74/235 (31%), Gaps = 40/235 (17%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 MP L + + + +RL+L Y+ + + LN L Sbjct: 23 MP-TLYHHPMSPASRFVRLILSEYG--YQTELSEEQPWENRRDFLTLN-------PAGTL 72 Query: 61 PYLIDGSRK-----------ITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMD--- 106 P +D S + + +++ IM+ R L E +R + + Sbjct: 73 PVYVDDSMRALCGATIISEYLDETSGIMK---RDRRLLAEDPFQRAEIRRLTEWFLQKME 129 Query: 107 -------NRMQLIMLCYNPDFEKQKPEFL------KTIPEKMKLYSEFLGKRPWFAGDKV 153 R ++ L PD P+ I + MK S G RPW AGD++ Sbjct: 130 ADVTRPLVRERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRI 189 Query: 154 TYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPI 208 +Y D A + P K++ R + + TP+ Sbjct: 190 SYGDLAAAAAISVLDYLGEIDWSDAPTAKEWYQRLKSRPSFRPLLAERVRGVTPV 244 >3M3M-A nrPDB Length = 210 Score = 56.5 bits (135), Expect = 8e-09, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 74/206 (35%), Gaps = 23/206 (11%) Query: 1 MPMILGYWNVR-GLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPN 59 M + Y + R G + I+L+L YE A D E F Sbjct: 1 MSLYKVYGDYRSGNCYKIKLMLNLLGLPYE------WQAVDILGGDTQTEAFLAKNPNGK 54 Query: 60 LPYLI--DGSRKITQSNAIMRYLARKHHLCGETEEERIRA---DIVENQVMDNRMQLIML 114 +P L DG+ + +SNAI+ +LA R + E + + + Sbjct: 55 IPVLELEDGTC-LWESNAILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARF 113 Query: 115 C--YNPDFEKQKPEFLKTIPE---KMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHI 169 Y E+++ E+LK + + + L + P+ G+ + D Y H+ Sbjct: 114 IQLYEGLPEERREEYLKLHKRGYKALDVMEKQLSRTPYLVGEHYSIADIALYA---YTHV 170 Query: 170 FEPK--CLDAFPNLKDFLARFEGLKK 193 + L +P ++ ++ R + + Sbjct: 171 ADEGGFDLSRYPGIQAWMQRVQSHPR 196 >3TOT-A nrPDB Length = 226 Score = 56.1 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 34/190 (17%), Positives = 62/190 (32%), Gaps = 22/190 (11%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI-DGSRKITQSNA 75 +R++L Y+ + N +P L+ D + S Sbjct: 17 VRVVLAEKKIDYQ--FVLEDVWNADTQIHQFN-------PLGKVPCLVMDDGGALFDSRV 67 Query: 76 IMRY---LARKHHLCGETEEERIRA---DIVENQVMDNRMQLIMLCYNPDFEKQKPEFLK 129 I Y L+ L + ER+ + + + ++D + L + E++ ++ Sbjct: 68 IAEYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRSESWIT 127 Query: 130 ----TIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKC--LDAFPNLKD 183 I E +K S L R W G+ +T D L +P+ + NL Sbjct: 128 RQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQHANLAA 187 Query: 184 FLARFEGLKK 193 F R E Sbjct: 188 FYTRIEKRPS 197 >2PMT-A nrPDB Length = 203 Score = 54.9 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 38/198 (19%), Positives = 66/198 (33%), Gaps = 13/198 (6%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L Y P ++L T + +R + +L K +P Sbjct: 1 MKLYYTPGSCSLSP-HIVLRETGLDFSIERIDLRTKKTESGKDFLAINPK-----GQVPV 54 Query: 63 LI-DGSRKITQSNAIMRYLAR---KHHLCG--ETEEERIRADIVENQVMDNRMQLIMLCY 116 L D +T+ AI++YLA +L + E + + + + L Sbjct: 55 LQLDNGDILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFS 114 Query: 117 NPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLD 176 + E P + K ++ L K+ GD T D + L Q+ L Sbjct: 115 SDTPESYLPVVKNKLKSKFVYINDVLSKQKCVCGDHFTVADAYLF-TLSQWAPHVALDLT 173 Query: 177 AFPNLKDFLARFEGLKKI 194 +L+D+LAR + Sbjct: 174 DLSHLQDYLARIAQRPNV 191 >1V2A-A nrPDB Length = 210 Score = 54.9 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 60/148 (40%), Gaps = 8/148 (5%) Query: 60 LPYLIDGSRKITQSNAIMRYLARKH----HLCGETEEERIRAD--IVENQVMDNRMQLIM 113 +P L+D + +S AI+ YL + L + + R + + + + + + Sbjct: 51 IPTLVDNGHVVWESYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDV 110 Query: 114 LCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPK 173 + E+ E ++ + + L +F+ +R + A D +T D + + + Sbjct: 111 IHLVMKKEQPSDEQMEKLKGALDLLEQFVTERAYAAADHLTVADICLLGTVTALNWLK-H 169 Query: 174 CLDAFPNLKDFLARFEG-LKKISAYMKS 200 L+ FP+++ +L R + + K Sbjct: 170 DLEPFPHIRAWLERVRAEMPDYEEFSKQ 197 >3UBL-A nrPDB Length = 242 Score = 54.9 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 50/164 (30%), Gaps = 18/164 (10%) Query: 25 DSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH 84 YE+ R A D+ + +P L + I +S AI+ +L Sbjct: 26 GLEYEQIRIAPSQEEDFLKIS----------PMGKIPVLEMDGKFIFESGAILEFLDTIF 75 Query: 85 ----HLCGETEEERIR---ADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKL 137 L E E R + +D + I L + E T+ + +K Sbjct: 76 PQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPEIVEEVHSTLVKGIKA 135 Query: 138 YSEFLGKRPWFAGDKVTYVDFLAYDILDQY-HIFEPKCLDAFPN 180 + P+ AG+ T D + L P + P Sbjct: 136 LQRVVRFSPYIAGNVFTLADCSGFAHLSVLDEELRPFYPNNHPL 179 >5F8B-A nrPDB Length = 244 Score = 53.4 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 41/117 (35%), Gaps = 16/117 (13%) Query: 57 FPNLPYLIDGS-RKITQSNAIMRYLARK---HHLCGETEEERIRA---------DIVENQ 103 +P K+ + AI Y+ + L G+ ++E +IV Sbjct: 47 LGKVPAFQGADSFKLFECMAIALYITSQNEQTTLLGKDKKEYAEIIKWMSFFNTEIVILM 106 Query: 104 VMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLA 160 QL ++ Y+ D Q F + + E+L R + GD+++ D Sbjct: 107 TQQLLPQLGVIPYDRD---QVEFFANMTQRSVDVVEEYLQDRTFLVGDQLSLADLFC 160 >2PVQ-A nrPDB Length = 201 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 33/191 (17%), Positives = 58/191 (30%), Gaps = 17/191 (8%) Query: 20 LLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDG-SRKITQSNAIMR 78 +L YE + + D + +P L ITQ+ AI++ Sbjct: 17 ILSEAGLPYELEAVDLKAKKTADGGDYFAVN-----PRGAVPALEVKPGTVITQNAAILQ 71 Query: 79 YLARKHHL------CGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIP 132 Y+ + G ER R D L E+ + + I Sbjct: 72 YIGDHSDVAAFKPAYGS--IERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVIANIN 129 Query: 133 EKMKLYSEFLG-KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGL 191 ++ L K ++ GD T D A I+ + + + L A+P R Sbjct: 130 RRLGQLEAMLSDKNAYWLGDDFTQPDAYASVII-GWGVGQKLDLSAYPKALKLRERVLAR 188 Query: 192 KKI-SAYMKSS 201 + A+ + Sbjct: 189 PNVQKAFKEEG 199 >4J2F-A nrPDB Length = 223 Score = 51.1 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 53/158 (33%), Gaps = 14/158 (8%) Query: 59 NLPYLIDGSRKITQSNAIMRYLARKHH---LCGETEEERIRADIVENQVMDNRMQLIMLC 115 +P L+ G + I +S I+ YL L ER A + D + + Sbjct: 53 KIPVLVHGGKPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIF 112 Query: 116 YNPDFEKQKPEFLKTIPEKMKLYSEF---LGKRPWFAGDKVTYVDF------LAYDILDQ 166 E +K +K E +K E + +F GDK+ VD ++++ Sbjct: 113 RTKGEELEK--AVKNCLEVLKTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEE 170 Query: 167 YHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYL 204 + FP L + F+ I + + Sbjct: 171 VAGVKVLESQKFPRLHAWTENFKEAPIIKENLPDRDQM 208 >3GH6-A nrPDB Length = 210 Score = 50.7 bits (120), Expect = 4e-07, Method: Composition-based stats. Identities = 33/173 (19%), Positives = 58/173 (33%), Gaps = 16/173 (9%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L Y + + + +++K A R Q+ E K+ +P Sbjct: 1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRA----REQFTPEYLKIN-PQHTIPT 55 Query: 63 LIDGSRKITQSNAIMRYLARKHH----LCGETEEERIRADIVENQVMDNRMQLIMLC--Y 116 L D + +S AIM YL K+ L + +++ + + D Y Sbjct: 56 LHDHGFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALIN--QRLYFDMGTLYKSFSEYY 113 Query: 117 NPDFEKQKP---EFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQ 166 P +KP E K I + + FL + + AG + D + Sbjct: 114 YPQIFLKKPANEENYKKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVST 166 >1E6B-A nrPDB Length = 221 Score = 49.5 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 63/204 (30%), Gaps = 17/204 (8%) Query: 14 THPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQS 73 H +R+ L YE + +D FK +P L+DG I S Sbjct: 20 AHRVRIALALKGLDYEYIPVNLLKGDQFDSD------FKKINPMGTVPALVDGDVVINDS 73 Query: 74 NAIMRYLARKH---HLCGETEEERI----RADIVENQVMDNR-MQLIMLCYNPDFEKQKP 125 AI+ YL K+ L +R IV + + ++ + +I ++K Sbjct: 74 FAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKT 133 Query: 126 EFLKTIPEK-MKLYSEFL--GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 ++ K + L GD++ D + ++ +P L Sbjct: 134 AWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQINMEPYPTLA 193 Query: 183 DFLARFEGLKKISAYMKSSRYLST 206 + L + + + Sbjct: 194 KCYESYNELPAFQNALPEKQPDAP 217 >4QQ7-A nrPDB Length = 207 Score = 49.5 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 27/197 (13%), Positives = 64/197 (32%), Gaps = 21/197 (10%) Query: 15 HPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSN 74 RL+L +E + + + P+ + +P L++ + +SN Sbjct: 18 QRCRLVLFEKGMDFEIRDVDLFNKPEDISVMN---------PYGQVPILVERDLILYESN 68 Query: 75 AIMRYLARKH---HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLK-- 129 I Y+ + L +R RA + +++ +L + + EK K Sbjct: 69 IINEYIDERFPHPQLMPADPVQRARARLF---LLNFEKELFVHVSTLENEKGKAAEKNHE 125 Query: 130 ----TIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFL 185 I +++ + K + G++ + +D +L + + + L + Sbjct: 126 KARLAIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRLDHYGIELSKNAAPLMKYA 185 Query: 186 ARFEGLKKISAYMKSSR 202 R + S Sbjct: 186 ERIFSRPAYIEALTPSE 202 >5J5N-A nrPDB Length = 231 Score = 48.0 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 35/198 (17%), Positives = 71/198 (35%), Gaps = 25/198 (12%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 +RL L YE +N K +P L+ + + +S I Sbjct: 31 VRLALAEKGVKYE--YSEEDLWNKSALLLQMNPVNK------QIPVLVHNGKPVCESLII 82 Query: 77 MRYLARKHH----LCGETEEERIR----ADIVENQVMDNRMQLIMLCYNPDFEKQKPEFL 128 ++Y+ L +R + AD V+ ++ D ++ + E K +F+ Sbjct: 83 VQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKK-GEEQEAAKKDFI 141 Query: 129 KTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEP----KCLDAFPNLKDF 184 + +KL LG +P+F G+ + YVD ++ +E P + + Sbjct: 142 DS----LKLMEGELGDKPYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKMIAY 197 Query: 185 LARFEGLKKISAYMKSSR 202 R + +S ++ + Sbjct: 198 CKRCLQKETVSKALEDPQ 215 >4CHS-A nrPDB Length = 219 Score = 47.6 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 35/191 (18%), Positives = 67/191 (35%), Gaps = 17/191 (8%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 +R+ L YE K + + K +P LI + I++S Sbjct: 19 VRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHK--------KIPVLIHNGKPISESLIA 70 Query: 77 MRYLARKHH----LCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIP 132 ++Y+ + L +R +A + V D ++ + ++K K Sbjct: 71 VQYIEEVWNDRNPLLPSDPYQRAQARFWADYV-DIKIHDLGKKIWTSKGEEKEAAKKEFI 129 Query: 133 EKMKLYSEFLGKRPWFAGDKVTYVDFLA---YDILDQYHIFEPKCLDA-FPNLKDFLARF 188 E +KL E LG + +F GD + +VD Y Y F ++ P + R Sbjct: 130 EALKLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENECPRFVAWAKRC 189 Query: 189 EGLKKISAYMK 199 + ++ + Sbjct: 190 LQKESVAKSLP 200 >3PR8-A nrPDB Length = 229 Score = 47.6 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 35/235 (14%), Positives = 76/235 (32%), Gaps = 31/235 (13%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M + L ++V + ++L L ++EE + G AP + Sbjct: 1 MSLKLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQALEVS----------PRGKV 50 Query: 61 PYLIDGSRKITQSNAIMRYLARKHH---LCGETEEERIRADIVENQVMDNRMQLIMLCY- 116 P L +++++ I+ Y+ + L + + + ++ CY Sbjct: 51 PVLETEHGFLSETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYA 110 Query: 117 --------NPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLA---YDILD 165 P +++ L +K F P+ AG+++T D + D+ + Sbjct: 111 ESFFGMSVEPLIKEKARADLLAGFATLKRNGRF---APYVAGEQLTLADLMFCFSVDLAN 167 Query: 166 QY--HIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 218 + L FP K L + + S P F ++ + + Sbjct: 168 AVGKKVLNIDFLADFPQAKALLQLMGENPHMPRILADKE-ASMPAFMEMIRSGKR 221 >4FQU-A nrPDB Length = 313 Score = 46.8 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 22/138 (15%), Positives = 46/138 (33%), Gaps = 15/138 (10%) Query: 72 QSNAIMRYLARKHHLCGETEEERI------RADIVENQV-MDNRMQLIMLCYNPDFEKQK 124 +S+ I+R L G + D + +V + + E + Sbjct: 137 ESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYE 196 Query: 125 PEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDIL-----DQYHIFEPKC--LDA 177 F + + E L R W GD++T D + L + F+ + Sbjct: 197 EAFYPLF-DTLDWLEEHLTGREWLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIAD 255 Query: 178 FPNLKDFLARFEGLKKIS 195 +PNL + + ++++ Sbjct: 256 YPNLSRLVGKLASHERVA 273 >3GX0-A nrPDB Length = 215 Score = 46.1 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 69/201 (34%), Gaps = 21/201 (10%) Query: 7 YWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID- 65 Y+ H I L LE + Y + D + +F +P ++D Sbjct: 5 YFAPTPNGHKITLFLEEAELDYRLIKV------DLGKGGQFRPEFLRISPNNKIPAIVDH 58 Query: 66 ----GS--RKITQSNAIMRYLARKHHLC--GETEEERIRADIVENQVMDNRMQLIM-LCY 116 G + +S AI+ YLA K L ET E + QV L + Sbjct: 59 SPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHF 118 Query: 117 NPDFEKQKPEFLKTIPEKMK----LYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEP 172 N + P ++ + + + ++ L PW G+ + D + ++ + + Sbjct: 119 NHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAW-TRQR 177 Query: 173 KCLDAFPNLKDFLARFEGLKK 193 L +P +K++ R Sbjct: 178 IDLAMYPAVKNWHERIRSRPA 198 >4IGJ-A nrPDB Length = 242 Score = 44.9 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 36/210 (17%), Positives = 62/210 (29%), Gaps = 21/210 (10%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI---DG-SRKITQ 72 +RL L +YE + A D + + +P L DG + + Q Sbjct: 39 VRLGLALKGLAYEYR------AVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQ 92 Query: 73 SNAIMRYLARKH---HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLK 129 S AI+ +L +H L R R + V + ++ P + + Sbjct: 93 SMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLREKVPGWDR 152 Query: 130 T-----IPEKMKLYSEFL--GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLK 182 I + + G + GD T D L F L+ +P L+ Sbjct: 153 EWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLD-LEPYPTLR 211 Query: 183 DFLARFEGLKKISAYMKSSRYLSTPIFSKL 212 L A + + P + Sbjct: 212 RVDEACAALAPFQAAHPDRQPDAPPPDRRT 241 >4G0L-A nrPDB Length = 328 Score = 44.9 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 48/154 (31%), Gaps = 18/154 (11%) Query: 60 LPYLIDGSRKIT---QSNAIMRYLARKHHLCGETEEERI------RADIVENQVMD-NRM 109 +P L D +S I+R G + + D + + D Sbjct: 133 VPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNN 192 Query: 110 QLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDIL----- 164 + + E E + + E + + LG+ + G+++T D + L Sbjct: 193 GVYKAGFATSQEAY-DEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDP 251 Query: 165 --DQYHIFEPKCLDAFPNLKDFLARFEGLKKISA 196 + + + + NL FL + I+ Sbjct: 252 VYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAE 285 >2VO4-A nrPDB Length = 219 Score = 44.9 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 56/154 (36%), Gaps = 21/154 (13%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 +R+ L YE K + + K +P LI + I +S Sbjct: 19 VRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHK--------KIPVLIHNGKPICESLIA 70 Query: 77 MRYLARKHH----LCGETEEERIR----ADIVENQVMDNRMQLIMLCYNPDFEKQKPEFL 128 ++Y+ + L +R + AD V+ ++ D ++ ++K Sbjct: 71 VQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWT-----SKGEEKEAAK 125 Query: 129 KTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYD 162 K E +KL E LG + +F GD + +VD Sbjct: 126 KEFIEALKLLEEQLGDKTYFGGDNLGFVDIALVP 159 >4PXO-A nrPDB Length = 238 Score = 44.9 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 42/212 (19%), Positives = 64/212 (30%), Gaps = 24/212 (11%) Query: 2 PMILGYWNVRGLTH-PIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 M+ Y N R +R+ L +YEE D D F + Sbjct: 22 SMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFL------DLDAGDQHKPDFLAINPQGAV 75 Query: 61 PYLIDGSRK-ITQSNAIMRYLARKHHLCGETEEE---------RIRA------DIVENQV 104 P L DG +TQS AI+ YL EE + + +V Sbjct: 76 PALFDGDGPPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRV 135 Query: 105 MDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDIL 164 M+ L E + F+ + S G + GD V++ D + Sbjct: 136 RTFLMENYGLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLW 195 Query: 165 DQYHIFEPKCLDAFPNLKDFLARFEGLKKISA 196 IF A+P +K L ++ Sbjct: 196 VGTGIFGIDT-AAYPTVKRISEEVLALDAVAR 226 >3PPU-A nrPDB Length = 352 Score = 44.5 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 32/173 (18%), Positives = 62/173 (35%), Gaps = 24/173 (13%) Query: 43 RSQWLNEKFKLGLDFPNLPYLID---GSRKITQSNAIMR-------YL----ARKHHLCG 88 + +L K F +P L D G+ +S+ I+R +L K L Sbjct: 142 KDLYLKVKPDYDGRF-TVPVLWDKHTGTIVNNESSEIIRMFNTAFNHLLPEDKAKLDLYP 200 Query: 89 ETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWF 148 E+ R + D V + V D + +K + + E + + L + + Sbjct: 201 ESL--RAKIDEVNDWVYDTVNNGVYKSGFASTQKAYEAAVIPLFESLDRLEKMLEGQDYL 258 Query: 149 AGDKVTYVDFLAYDILDQYHIFEPKCLDAFP-NLKDFLARFEGLKKISAYMKS 200 G ++T D + + + F+P + F NL+ G + +M+ Sbjct: 259 IGGQLTEADIRLFVTIVR---FDPVYVTHFKCNLRTIRD---GYPNLHRWMRK 305 >1N2A-A nrPDB Length = 201 Score = 43.4 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 53/147 (36%), Gaps = 7/147 (4%) Query: 56 DFPNLPYLIDGSRKIT-QSNAIMRYLARKHH----LCGETEEERIRADIVENQVMDNRMQ 110 +P L+ + + AIM+YLA L R + N + + Sbjct: 48 PKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIATELHK 107 Query: 111 LIMLCYNPDF-EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHI 169 + PD E+ KP + +K++ +E L W G + T D + +L + Sbjct: 108 GFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVLRWAYA 167 Query: 170 FEPKCLDAFPNLKDFLARFEGLKKISA 196 + L+ ++ F+ R ++ Sbjct: 168 VKLN-LEGLEHIAAFMQRMAERPEVQD 193 >5NR1-A nrPDB Length = 228 Score = 43.0 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 32/208 (15%), Positives = 65/208 (31%), Gaps = 28/208 (13%) Query: 4 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 L ++ + + +RL L + E + + P +F P L Sbjct: 6 TLHHFPLDPASRQVRLALGEKRLPFVEMQVRYWEMP---------PEFTSLNPSGMPPVL 56 Query: 64 IDGSRK----ITQSNAIMRYLARKHH---LCGETEEERIRA------------DIVENQV 104 ++ + I ++ AI+ ++ L G ER A + V + Sbjct: 57 VETKHQRNLVICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFL 116 Query: 105 MDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDIL 164 + +M+ +L + + + + L R W AG +++ DF A L Sbjct: 117 LHEKMEKRLLRMGAPDLAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHL 176 Query: 165 DQYHIFEPKCLDAFPNLKDFLARFEGLK 192 F F K + + + Sbjct: 177 SVIDYFGDVPWKDFQAAKTWYMKLKSRP 204 >4BVY-B nrPDB Length = 186 Score = 41.8 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 23/152 (15%), Positives = 53/152 (34%), Gaps = 19/152 (12%) Query: 59 NLPYLI-DGSRKITQSNAIMRYLARKHH---LCGETEEERIRADIVENQVMDNRMQLIML 114 +P L + +T I +L ++ + L G T EE+ + Q ++ R+ + Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKA----IVQQWLEYRVTQV-- 94 Query: 115 CYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLA-YDILDQYHIFEPK 173 I +K + +L + + G T D L Y + + Sbjct: 95 --------DGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQ 146 Query: 174 CLDAFPNLKDFLARFEGLKKISAYMKSSRYLS 205 + + N+ + + + I ++ S ++ Sbjct: 147 EKEKYLNVSRWFSHIQHYPGIRQHLSSVVFIK 178 >5ECL-B nrPDB Length = 223 Score = 41.8 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 35/212 (16%), Positives = 70/212 (33%), Gaps = 18/212 (8%) Query: 1 MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNL 60 +P++L YW R+ L +E Y D + + + Sbjct: 10 LPILLDYWPSMFGMRA-RVALREKGVEFE---YREEDFSNKSPLLLQSNPIHK-----KI 60 Query: 61 PYLIDGSRKITQSNAIMRYL----ARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCY 116 P L+ + + +S +++Y+ K+ R +A + +D + Sbjct: 61 PVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWAD-FVDKKFTDAQFKV 119 Query: 117 NPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEP---- 172 +++ K E +K+ LG +P+F GD YVD + +E Sbjct: 120 WGKKGEEQEAGKKEFIEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNF 179 Query: 173 KCLDAFPNLKDFLARFEGLKKISAYMKSSRYL 204 P L + R + +S + S + Sbjct: 180 SIESESPKLIAWAKRCMEKESVSKSLPDSEKI 211 >6GCB-A nrPDB Length = 325 Score = 41.8 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 32/210 (15%), Positives = 67/210 (31%), Gaps = 34/210 (16%) Query: 9 NVRGLTHPIRL-----LLEYTDSSYEEKRYAMGDAPD------YDRSQWLNEKFKLGLDF 57 ++GL + + L + + G D Y R +L K F Sbjct: 67 KIKGLEEIVGVTIVSPLFSAHGWPFGDVSPFPGAEADPFYNAQYVRDLYLRADPKYEGRF 126 Query: 58 PNLPYLIDGSRKIT---QSNAIMRYLARKHH-----------LCGETEEERIRADIVENQ 103 +P L D + +S+ I+R + L E + D + Sbjct: 127 -TVPVLWDKKTETVVNNESSEIIRIFNTAFNEFLPADKAAIHLYPEALK--SEIDEINEW 183 Query: 104 VMD-NRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYD 162 V D + + ++ + + E + + L + + GD++T D + Sbjct: 184 VYDTVNNGVYKAGF-ATTQQAYEAAVIPLFESLDRLEKILTGKDYLVGDQLTEADVRLFV 242 Query: 163 ILDQYHIFEPKCLDAFP-NLKDFLARFEGL 191 + + F+P + F NL+ + + Sbjct: 243 TIIR---FDPAYVGHFKCNLRTIRDGYPAI 269 >2JL4-A nrPDB Length = 213 Score = 41.1 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 37/196 (18%), Positives = 65/196 (33%), Gaps = 22/196 (11%) Query: 3 MILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62 M L + G +H +R+ L YE A + + L + FK +P Sbjct: 2 MKLYNFWRSGTSHRLRIALNLKGVPYE------YLAVHLGKEEHLKDAFKALNPQQLVPA 55 Query: 63 LIDGSRKITQSNAIMRYLARKH---HLCGETEEERIRADIVENQVM-DNR-------MQL 111 L G++ + QS AI+ +L ++ L + R R + V D ++ Sbjct: 56 LDTGAQVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEY 115 Query: 112 IMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRP----WFAGDKVTYVDFLAYDILDQY 167 + + D I Y L P + GD T D ++ Sbjct: 116 LRKTFGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESA 175 Query: 168 HIFEPKCLDAFPNLKD 183 F+ L +P ++ Sbjct: 176 RRFQVD-LTPYPLIRA 190 >6GZF-A nrPDB Length = 341 Score = 40.7 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 50/139 (35%), Gaps = 20/139 (14%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLID---GSRKITQSNAIMRYLARKHH--------LCG 88 DY R ++ + +P L D + +S IMR + L Sbjct: 115 DYLRELYVRAAPDVTCRV-TVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYP 173 Query: 89 ETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEK---MKLYSEFLGKR 145 E +E+ D + + + + Y F ++ + + + E + + + L + Sbjct: 174 EGYQEK--VDQIID---NIYEPINNGVYRAGFATEQEPYDEAVAELFGALAHWDDVLADQ 228 Query: 146 PWFAGDKVTYVDFLAYDIL 164 + AGD++T D + L Sbjct: 229 RYLAGDRLTEADIAMFTTL 247 >6GC9-A nrPDB Length = 327 Score = 40.3 bits (93), Expect = 6e-04, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 38/108 (35%), Gaps = 7/108 (6%) Query: 94 RIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKV 153 R D + V D + +K + + E + + L + + GD++ Sbjct: 175 RGEIDGINEWVYDTVNNGVYKSGFATSQKAYEAAVVPLFESLDRLEKILTGKDYLVGDQL 234 Query: 154 TYVDFLAYDILDQYHIFEPKCLDAFP-NLKDFLARFEGLKKISAYMKS 200 T D + + + F+P + F N++ G I +M+ Sbjct: 235 TEADIRLFVTIVR---FDPVYVGHFKCNIRTIRD---GYPAIDLWMRK 276 >4USS-A nrPDB Length = 325 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 24/156 (15%), Positives = 56/156 (35%), Gaps = 23/156 (14%) Query: 60 LPYLIDGSRKIT---QSNAIMRYLARKHHLCGET-------EEERIRADIVENQVMDNRM 109 +P L D K +S+ I+R + + E + + D V D Sbjct: 129 VPVLWDKKLKTIVNNESSEIIRMFNTEFNDIAENAALDLYPSHLQAQIDETNGWVYD--- 185 Query: 110 QLIMLCYNPDFEKQKPEFLKT---IPEKMKLYSEFLGKRPWFAGDKVTYVDFLAY----- 161 + Y F +++ + + + E + E LG++ + G+ ++ D + Sbjct: 186 GINNGVYKCGFARKQGPYEEAAIQLYEALDKCEEILGRQRYICGNTLSEADIKLFVTLIR 245 Query: 162 --DILDQYHIFEPKCLDAFPNLKDFLARFEGLKKIS 195 ++ + K L +PN+ ++ + +S Sbjct: 246 FDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMS 281 >3C8E-A nrPDB Length = 288 Score = 39.1 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 27/198 (13%), Positives = 59/198 (29%), Gaps = 29/198 (14%) Query: 19 LLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSR----KITQSN 74 L L T + Y+ +GD + F +P L D + ++ +S Sbjct: 66 LALGVTGAEYDAWLIRIGDGDQFSS------GFVEVNPNSKIPALRDHTHNPPIRVFESG 119 Query: 75 AIMRYLARKHHLCGETEEERIRADI-----VENQVMDNRMQL-IMLCYNP-DFEKQKPEF 127 +I+ YLA K + + + ++ Y P E F Sbjct: 120 SILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRF 179 Query: 128 LKTIPEKMKLYSEFLGKRPWFAGDKVTYVD---------FLAYDILDQYHIFEPKCLDAF 178 + + + L + + AGD+ T D + + D + ++ Sbjct: 180 TMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAG---SY 236 Query: 179 PNLKDFLARFEGLKKISA 196 +++ + + Sbjct: 237 KHVQRWAKEVGERPAVKR 254 >4PTS-A nrPDB Length = 348 Score = 38.0 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 32/104 (30%), Gaps = 6/104 (5%) Query: 94 RIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKV 153 R D V + + C + + K+ SE L ++ + GD + Sbjct: 168 RAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQRYLVGDTI 227 Query: 154 TYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKISAY 197 T D + L ++ K ++ + + AY Sbjct: 228 TEADVRLFTTLARFDAVYHGHF------KCNRSKLSEMPVLWAY 265 >6EP7-A nrPDB Length = 220 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 54/152 (35%), Gaps = 9/152 (5%) Query: 59 NLPYLIDGSRKITQSNAIMRYL----ARKHHLCGETEEERIRADIVENQVMDNRMQLIML 114 +P LI + I +S ++Y+ + + +R +A + + Sbjct: 53 KIPVLIHEGKPICESIIQVQYIDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKA 112 Query: 115 CYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDIL----DQYHIF 170 ++ EKQ+ ++ I E +K LG + +F G++ VD + Sbjct: 113 LWSESGEKQEAAKIEFI-EVLKTLDSELGDKYYFGGNEFGLVDIAFIGFYSWFRTYEEVA 171 Query: 171 EPKCLDAFPNLKDFLARFEGLKKISAYMKSSR 202 + FP L + R + ++ + S Sbjct: 172 NLSIVLEFPKLMAWAQRCLKRESVAKALPDSD 203 >3RBT-A nrPDB Length = 246 Score = 37.6 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 32/204 (15%), Positives = 77/204 (37%), Gaps = 33/204 (16%) Query: 5 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64 L + ++ H + L+LE YE R P++ R++ K P L Sbjct: 29 LYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLKI---------PVLE 79 Query: 65 D----GSRKITQSNAIMRYLARK---HHLCGETE----EERIRADIVENQVMDNRMQLIM 113 G R + +S I YL K H L ++R+ + + + Sbjct: 80 IPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSLE---- 135 Query: 114 LCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPK 173 C++ +F + ++T+ K + +F G++ +D++ + +++ ++ + Sbjct: 136 -CFDTNFAFGSEQIIQTLEIFEKELTNR--GTNYFGGNRPGMLDYMVWPWVERLYLL--R 190 Query: 174 CLDAFPNLKDFLARFEGLKKISAY 197 C++ + F+ + + + Sbjct: 191 CVND----RKFVEKKSLFPNFADW 210 >5N9U-A nrPDB Length = 218 Score = 36.8 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 59/183 (32%), Gaps = 30/183 (16%) Query: 2 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 P ILG + L LE Y+ +GD P QW E +P Sbjct: 14 PNILGDCPF---CQRVLLSLEEKKIPYKSHLINLGDKP-----QWFLE----ISPEGKVP 61 Query: 62 YLIDGSRKITQSNAIMRYLARKHH---LCGETEEERIRA-DIVENQVMDNRMQLIMLCYN 117 + + + S+ I+ L K+ L T E + + + Sbjct: 62 VVKIDDKWVADSDVIVGILEEKNPEPPLA--TPPEFASVGSKIFPSFVKFLK-----SKD 114 Query: 118 PDFEKQKPEFLKTIPEKMKLYSEFLG-KRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLD 176 P+ + + + E++K L P+ AG+K+T VD L + Sbjct: 115 PNDGTE-----QALLEELKALDGHLKVHGPFIAGEKITAVDLSLAPKLYHLEVAL-GHFK 168 Query: 177 AFP 179 +P Sbjct: 169 NWP 171 >5ELG-A nrPDB Length = 221 Score = 36.4 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 30/195 (15%), Positives = 60/195 (30%), Gaps = 28/195 (14%) Query: 19 LLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMR 78 L LE +Y+ + D P QW F +P L + +T S+ I+ Sbjct: 28 LTLEEKSLTYKIHLINLSDKP-----QW----FLDISPQGKVPVLKIDDKWVTDSDVIVG 78 Query: 79 YLARKH-HLCGETEEERIRA-DIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMK 136 L K+ +T E + + + +++ Sbjct: 79 ILEEKYPDPPLKTPAEFASVGSNIFGTFGTFL----------KSKDSNDGSEHALLVELE 128 Query: 137 LYSEFLGKR--PWFAGDKVTYVDFLAYDILDQYHIFEPKC-----LDAFPNLKDFLARFE 189 L P+ AG++V+ VD L + ++FP++ +++ Sbjct: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTLF 188 Query: 190 GLKKISAYMKSSRYL 204 L +Y+ Sbjct: 189 SLDSFEKTKTEEKYV 203 >5LOL-A nrPDB Length = 215 Score = 36.1 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 51/160 (31%), Gaps = 29/160 (18%) Query: 18 RLLLEYTDSS--YEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNA 75 R+LL + Y+ + D P QW F +P + + + S+ Sbjct: 27 RVLLTLEEKKLPYKTHLINVSDKP-----QW----FLDISPEGKVPVVKLDGKWVADSDV 77 Query: 76 IMRYLARKH---HLCGETEEERIRA-DIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTI 131 I+ L K+ L +T E + + + K + Sbjct: 78 IVGLLEEKYPEPSL--KTPPEFASVGSKIFGAFVTFL----------KSKDANDGSEKAL 125 Query: 132 PEKMKLYSEFLGKR--PWFAGDKVTYVDFLAYDILDQYHI 169 ++++ L P+ AG+K+T VD L + Sbjct: 126 VDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEV 165 >3M1G-A nrPDB Length = 362 Score = 35.3 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 21/65 (32%), Gaps = 6/65 (9%) Query: 135 MKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKI 194 + + L R + GD +T D Y L ++ K + + + Sbjct: 223 LDWLEDRLSTRRYLMGDHITEADIRLYPTLVRFDAVYHGHF------KCGRNKITEMPNL 276 Query: 195 SAYMK 199 Y++ Sbjct: 277 WGYLR 281 >3IR4-A nrPDB Length = 218 Score = 33.4 bits (75), Expect = 0.085, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 50/168 (29%), Gaps = 20/168 (11%) Query: 33 YAMGDAPDYDRSQWLNEKFKLGLDFPN--LPYLI-DGSRKITQSNAIMRYLARKHHLCGE 89 + + + P +++ +P L D SR + +S I+ Y+ +L G+ Sbjct: 22 FGLKNIPVELNVLQNDDEATPTRMIGQKMVPILQKDDSRYLPESMDIVHYVD---NLDGK 78 Query: 90 TEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPE----------FLKTIPEKMKLYS 139 R +E + + P F K + F++ + Sbjct: 79 PLLTGKRNPAIEEWLRKV-NGYVNQLLLPRFAKSAFDEFSTPAARQYFIRKKEASSGSFD 137 Query: 140 EFLGKRPWFA---GDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDF 184 L GD + +D L + FP L++ Sbjct: 138 NHLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGELSEDDIHLFPLLRNL 185 >6JWK-A nrPDB Length = 222 Score = 32.6 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 7/65 (10%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLID-GSRKITQSNA 75 +R+ L Y+ + + + L + LP L+D R+ +QS A Sbjct: 15 VRIALALKGLDYQVVPV------NLRQGEQLRPADRQRNPMGALPTLVDADGRRFSQSLA 68 Query: 76 IMRYL 80 I+ YL Sbjct: 69 IIDYL 73 >5HSX-A nrPDB Length = 323 Score = 31.8 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 21/60 (35%), Gaps = 4/60 (6%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 +R + ++ + R AP + + ++P DG TQS AI Sbjct: 254 VRFKWQAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDG----TQSVAI 309 >1GWC-A nrPDB Length = 230 Score = 31.8 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 38/203 (18%), Positives = 60/203 (29%), Gaps = 33/203 (16%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 ++L L SYE+ D + L K +P LI + +S I Sbjct: 21 VKLALALKGLSYEDVE------EDLYKKSELLLKSNPV--HKKIPVLIHNGAPVCESMII 72 Query: 77 MRYLARKH-----HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLK-- 129 ++Y+ L ER A V D + E++K E K Sbjct: 73 LQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTEEEKSEGKKQA 132 Query: 130 ---------TIPEKMKLYSEFLGKRPWFA----GDKVTYVDFLAYDILDQYHIFEPKCLD 176 + E K F G G +++ + L IF+ Sbjct: 133 FAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSW--MKVTEALSGDKIFDA---A 187 Query: 177 AFPNLKDFLARFEGLKKISAYMK 199 P L ++ RF L A + Sbjct: 188 KTPLLAAWVERFIELDAAKAALP 210 >5KEU-A nrPDB Length = 323 Score = 31.4 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 20/60 (33%), Gaps = 4/60 (6%) Query: 17 IRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAI 76 +R E ++ + R AP + + ++P DG QS AI Sbjct: 254 VRFKWEAGSVAFWDNRATAHLAPTDIFDLDFDRQLYRTTLVGDVPVGPDGR----QSVAI 309 >2JZR-A nrPDB Length = 144 Score = 31.4 bits (70), Expect = 0.32, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 21/51 (41%), Gaps = 7/51 (13%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKHHLCGET 90 D D +W GL++P LP + D I QS I Y L G+ Sbjct: 74 DGDFQKWYA-----GLNYPKLPVVTDNGGTIAQSLNISVY--PSWALIGKD 117 >2YV7-A nrPDB Length = 260 Score = 31.0 bits (69), Expect = 0.43, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 44/122 (36%), Gaps = 18/122 (14%) Query: 61 PYLIDGSRKITQSNAIMRYLARK----HHLCGETEEERIRADIVENQVMDNRMQLIMLCY 116 P LID I ++ I R++ + ++L + +E V + + ++L ++ Sbjct: 85 PILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKE-------VATLIENLYVKLKLMLV 137 Query: 117 NPDFEKQKPEFLKTIPEKMKLYSEFLGKRP--WFAGDKVTYVDFLAYDILDQYHIFEPKC 174 D K + ++ ++ L R + GD + D L + Sbjct: 138 KKDEAKN-----NALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYF 192 Query: 175 LD 176 +D Sbjct: 193 VD 194 >3BBY-A nrPDB Length = 215 Score = 30.3 bits (67), Expect = 0.67, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 20/45 (44%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKH 84 D D + L ++ +P L ++++S+AI YL + Sbjct: 40 DLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRF 84 >4J15-A nrPDB Length = 521 Score = 29.9 bits (66), Expect = 0.80, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 39/123 (31%), Gaps = 31/123 (25%) Query: 85 HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGK 144 L G +E+ D ++D + Y + P++ Y F+ Sbjct: 394 KLLGHLVKEKYDTDFY---ILDKYPLAVRPFYTMPDPRN--------PKQSNSYDMFMRG 442 Query: 145 RPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYL 204 +G + I +P+ L + L+KI AY+ S R+ Sbjct: 443 EEILSGAQ---------------RIHDPQLLTE----RALHHGI-DLEKIKAYIDSFRFG 482 Query: 205 STP 207 + P Sbjct: 483 APP 485 >1XX7-A nrPDB Length = 184 Score = 29.9 bits (66), Expect = 0.83, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 31/88 (35%), Gaps = 8/88 (9%) Query: 115 CYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKC 174 Y E + +PE +L+ E+ K G V D LD Sbjct: 91 KYLNKEEAEAKALKDVLPEYTELFEEY-SKALTLEGQLVKIAD-----KLDMIIQAYEYE 144 Query: 175 LDAFPNLKDFLARFEGLKK--ISAYMKS 200 L NL +F E L+K IS Y++ Sbjct: 145 LSGAKNLSEFWNALEDLEKLEISRYLRE 172 >2RAS-A nrPDB Length = 212 Score = 29.9 bits (66), Expect = 0.88, Method: Composition-based stats. Identities = 7/48 (14%), Positives = 15/48 (31%) Query: 94 RIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEF 141 + D + ++P E + +P + K+Y F Sbjct: 45 QANLSRYFETREDLMEAIADYWFHPMVEIMEDVLASDLPPRRKMYEFF 92 >5E1J-A nrPDB Length = 741 Score = 29.5 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 41/126 (32%), Gaps = 18/126 (14%) Query: 78 RYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKL 137 R L + L ++ D NQ + QL P K++ + Sbjct: 325 RMLEKAFGLI--DSDKNGEIDK--NQCIKLFEQLTNYRTLPKISKEEFGLI--------- 371 Query: 138 YSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKISAY 197 + E R + +K + D L P + FP + + + ++ A+ Sbjct: 372 FDELDDTRDFKI-NKDEFADLCQAIALRFQKEEVPSLFEHFPQI--YHSALSQ--QLRAF 426 Query: 198 MKSSRY 203 ++S + Sbjct: 427 VRSPNF 432 >1G6W-A nrPDB Length = 261 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 28/208 (13%), Positives = 58/208 (27%), Gaps = 48/208 (23%) Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLID---GSRKITQSNAIMRYLARKHH----------- 85 D++ + +F +P LID + I +S AI+ +L K++ Sbjct: 52 DFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSD 111 Query: 86 ---------------------LCGETEEERI----RADIVENQVMDNRMQLIMLCYNPDF 120 + G+ R + + D ++ + Sbjct: 112 DLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALA 171 Query: 121 EKQKPEFLKTIPEKMKLY---------SEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFE 171 E+++ ++ E Y S F W GDK+T D + Sbjct: 172 ERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIG 231 Query: 172 PKCLDAFPNLKDFLARFEGLKKISAYMK 199 FP + + + ++ Sbjct: 232 INIKIEFPEVYKWTKHMMRRPAVIKALR 259 >1QO0-A nrPDB Length = 385 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 27/79 (34%), Gaps = 7/79 (8%) Query: 23 YTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKIT-QSNAIMRYLA 81 Y Y G AP+ + + + + I +SN +MR+L Sbjct: 108 YEGFEYSPNIVYGGPAPNQNSAPLAAYLIR---HYGERVVFIGSDYIYPRESNHVMRHLY 164 Query: 82 RKHHLCGETEEERIRADIV 100 R+H G T E I + Sbjct: 165 RQH---GGTVLEEIYIPLY 180 >3NIV-A nrPDB Length = 222 Score = 29.1 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 41/126 (32%), Gaps = 15/126 (11%) Query: 60 LPYLIDGSRKITQSNAIMRYLARKH---HLCGETE-EERIRADIVENQVMDNR------- 108 +P L + ++QS AI+ YL H L + + + D Sbjct: 56 VPSLDINGQILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRV 115 Query: 109 MQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLG----KRPWFAGDKVTYVDFLAYDIL 164 + + +N + E+ + + + E LG +P G +V D + Sbjct: 116 LNRLKEQFNANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQV 175 Query: 165 DQYHIF 170 H F Sbjct: 176 YNAHRF 181 >2IWR-A nrPDB Length = 178 Score = 28.4 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 21/38 (55%) Query: 66 GSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQ 103 G + +S+ I R+L + + +TE E+ + +++ + Sbjct: 14 GDARSGKSSLIHRFLTGSYQVLEKTESEQYKKEMLVDG 51 >4K0G-A nrPDB Length = 251 Score = 28.4 bits (62), Expect = 2.5, Method: Composition-based stats. Identities = 20/139 (14%), Positives = 38/139 (27%), Gaps = 32/139 (23%) Query: 55 LDFPNLPYLIDGSRKITQSNAIMRYL------ARKHHLCGETEEERIRADIVENQVMDNR 108 LP+L+ G+ T +N I +L R L E +D Sbjct: 69 CPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNT-------AGLDIF 121 Query: 109 MQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFL------------------GKRPWFAG 150 + K + + +K+ +L +R + G Sbjct: 122 AKFSAYI-KNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDG 180 Query: 151 DKVTYVDFLAYDILDQYHI 169 +++T D L + Sbjct: 181 NELTLADCNLLPKLHIVQV 199 >6AIY-A nrPDB Length = 378 Score = 28.4 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 17/40 (42%) Query: 116 YNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTY 155 Y P E+ + + ++ ++ G W AG VT+ Sbjct: 86 YQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTW 125 >1XA6-A nrPDB Length = 466 Score = 28.0 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 26/103 (25%), Gaps = 8/103 (7%) Query: 95 IRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFL--------GKRP 146 R + D +M D + I +KLY L Sbjct: 310 YRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSK 369 Query: 147 WFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFE 189 + K++ D + + + P + L L + Sbjct: 370 FIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVT 412 >3FQJ-A nrPDB Length = 417 Score = 28.0 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 17/40 (42%) Query: 116 YNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTY 155 Y P E+ + + ++ ++ G W AG VT+ Sbjct: 112 YQPRDEEVQERLDHLLRWVLEHRNQLEGGPGWLAGATVTW 151 >2PAR-A nrPDB Length = 201 Score = 27.6 bits (60), Expect = 3.8, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 27/73 (36%), Gaps = 1/73 (1%) Query: 80 LARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYS 139 +A+++ + +++ D+V ++ D LI D EK + + +K Sbjct: 91 IAQEYKAIEKIAQQK-LVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLE 149 Query: 140 EFLGKRPWFAGDK 152 E F K Sbjct: 150 ELAAGNNEFLLAK 162 >2H30-A nrPDB Length = 164 Score = 27.6 bits (60), Expect = 4.1, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 27/70 (38%), Gaps = 4/70 (5%) Query: 23 YTDSSYEEKRYAMGDAPDYDRSQWLNE--KFKLGLDFPNLPYLIDGSRKITQSNAIMRYL 80 D+ + +P + + E K+ GL++P LP + D I Q+ I Y Sbjct: 64 AQDAKFSSANLITVASPGFLHEKKDGEFQKWYAGLNYPKLPVVTDNGGTIAQNLNISVY- 122 Query: 81 ARKHHLCGET 90 L G+ Sbjct: 123 -PSWALIGKD 131 >3CXL-A nrPDB Length = 463 Score = 27.2 bits (59), Expect = 5.0, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 29/110 (26%), Gaps = 8/110 (7%) Query: 88 GETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFL----- 142 G E R + + D +M D E + I +KLY L Sbjct: 300 GLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLI 359 Query: 143 ---GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFE 189 + K+ D + + + P + L L R Sbjct: 360 TYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVT 409 >2QB5-A nrPDB Length = 347 Score = 27.2 bits (59), Expect = 5.4, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 162 DILDQYHIFEPKCLDAFPNLKDFLAR---FEGLKKISAYMKSSRYLSTP 207 + +D + LD P ++ L R +E ++KI AYM+ R S P Sbjct: 95 EYIDAHPETI--VLDPLPAIRTLLDRSKSYELIRKIEAYMEDDRICSPP 141 >4XRU-B nrPDB Length = 394 Score = 27.2 bits (59), Expect = 5.7, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 46/130 (35%), Gaps = 10/130 (7%) Query: 69 KITQSNAIMRYLARKHHLCGETEEERIRADIV--ENQVMDNRMQLIMLCYNPD---FEKQ 123 KI Q A + ++A L + +++ I+ + D + L + Y + F++Q Sbjct: 161 KIQQEPAYLSFVADAKVLSAKELKDKYPMHIIRQYQSIRDFKF-LDLPHYQQNIQLFKRQ 219 Query: 124 KPEFLKTIPEKMKLY----SEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFP 179 F K K + + R F D +++ D L +P Sbjct: 220 LDIFGKEAAPFFKPFNILKEVYTDGREHFVNDNLSFQQINDDDFLHYQFTDREDFEAKYP 279 Query: 180 NLKDFLARFE 189 ++ ++ + Sbjct: 280 QIRAWVDQVN 289 >4CZI-A nrPDB Length = 348 Score = 27.2 bits (59), Expect = 5.7, Method: Composition-based stats. Identities = 14/34 (41%), Positives = 20/34 (58%), Gaps = 3/34 (8%) Query: 63 LIDGSRKITQSNAIMRYLARKHHLC-GETEEERI 95 + G K+ + AI+ Y+ R H+L GET ERI Sbjct: 177 VRVGGDKMDE--AIISYMRRHHNLLIGETTAERI 208 >2OSA-A nrPDB Length = 202 Score = 26.8 bits (58), Expect = 6.8, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 29/110 (26%), Gaps = 8/110 (7%) Query: 88 GETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFL----- 142 G E R + + D +M D E + I +KLY L Sbjct: 39 GLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLI 98 Query: 143 ---GKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFE 189 + K+ D + + + P + L L R Sbjct: 99 TYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVT 148 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.147 0.414 Lambda K H 0.267 0.0449 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,635,273 Number of Sequences: 36641 Number of extensions: 403738 Number of successful extensions: 1401 Number of sequences better than 10.0: 149 Number of HSP's better than 10.0 without gapping: 178 Number of HSP's successfully gapped in prelim test: 52 Number of HSP's that attempted gapping in prelim test: 1037 Number of HSP's gapped (non-prelim): 238 length of query: 218 length of database: 10,336,785 effective HSP length: 93 effective length of query: 125 effective length of database: 6,929,172 effective search space: 866146500 effective search space used: 866146500 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 57 (26.4 bits)